# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Abhydrolase_2 PF02230.11 KUM55324.1 - 2e-12 47.0 0.0 2.2e-12 46.9 0.0 1.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KUM55324.1 - 9.7e-09 35.4 1.3 1.9e-06 27.9 0.3 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM55324.1 - 6.6e-06 25.9 0.2 1.3e-05 24.9 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Connexin_CCC PF10582.4 KUM55327.1 - 0.073 12.8 0.0 0.08 12.7 0.0 1.1 1 0 0 1 1 1 0 Gap junction channel protein cysteine-rich domain Condensation PF00668.15 KUM55328.1 - 6.8e-48 163.0 0.4 8e-48 162.8 0.3 1.1 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 KUM55328.1 - 1.8e-14 53.7 0.0 3.4e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site SepZ PF06066.6 KUM55328.1 - 0.12 12.4 0.0 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 SepZ HTH_psq PF05225.11 KUM55329.1 - 3.8e-13 48.7 0.0 4.8e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain CENP-B_N PF04218.8 KUM55329.1 - 0.00012 21.4 0.1 0.00018 20.8 0.0 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.1 KUM55329.1 - 0.00016 21.6 0.1 0.0002 21.2 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.1 KUM55329.1 - 0.00018 20.8 0.3 0.00028 20.2 0.2 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 KUM55329.1 - 0.00029 20.4 0.1 0.00039 20.0 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_23 PF13384.1 KUM55329.1 - 0.0019 17.7 0.1 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain TrmB PF01978.14 KUM55329.1 - 0.0064 16.1 0.0 0.0085 15.7 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB BrkDBD PF09607.5 KUM55329.1 - 0.0086 15.6 0.1 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Brinker DNA-binding domain HTH_10 PF04967.7 KUM55329.1 - 0.015 14.8 1.8 0.021 14.4 0.0 2.2 2 1 0 2 2 2 0 HTH DNA binding domain UPF0175 PF03683.8 KUM55329.1 - 0.021 14.3 0.1 0.041 13.3 0.1 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0175) HTH_7 PF02796.10 KUM55329.1 - 0.025 14.4 0.1 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase NUMOD1 PF07453.8 KUM55329.1 - 0.025 14.3 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 NUMOD1 domain HTH_3 PF01381.17 KUM55329.1 - 0.026 14.3 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix Sigma70_r4 PF04545.11 KUM55329.1 - 0.04 13.2 0.2 0.073 12.4 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Rrf2 PF02082.15 KUM55329.1 - 0.053 13.6 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator HTH_30 PF13556.1 KUM55329.1 - 0.059 12.9 0.1 0.12 11.9 0.0 1.5 1 1 1 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_IclR PF09339.5 KUM55329.1 - 0.062 12.9 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain SRP19 PF01922.12 KUM55329.1 - 0.066 13.8 0.1 0.077 13.5 0.0 1.1 1 0 0 1 1 1 0 SRP19 protein Sigma70_r4_2 PF08281.7 KUM55329.1 - 0.066 12.6 0.0 0.51 9.8 0.0 2.1 1 1 0 1 1 1 0 Sigma-70, region 4 MerR_1 PF13411.1 KUM55329.1 - 0.085 12.6 0.0 0.37 10.5 0.0 1.9 1 1 1 2 2 2 0 MerR HTH family regulatory protein MerR PF00376.18 KUM55329.1 - 0.097 12.2 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 MerR family regulatory protein HTH_6 PF01418.12 KUM55329.1 - 0.13 11.9 0.2 0.22 11.2 0.0 1.5 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family HTH_AsnC-type PF13404.1 KUM55329.1 - 0.2 11.2 0.8 0.42 10.2 0.5 1.7 1 1 0 1 1 1 0 AsnC-type helix-turn-helix domain zf-CCHC PF00098.18 KUM55330.1 - 9.6e-05 22.1 4.1 0.00016 21.4 2.8 1.4 1 0 0 1 1 1 1 Zinc knuckle HALZ PF02183.13 KUM55330.1 - 0.0032 17.1 2.6 0.0076 15.9 1.8 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper zf-CCHC_3 PF13917.1 KUM55330.1 - 0.0091 15.7 0.6 0.0091 15.7 0.4 2.3 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_2 PF13696.1 KUM55330.1 - 0.032 13.7 0.3 0.053 13.0 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle UBN2 PF14223.1 KUM55330.1 - 0.12 12.1 1.8 0.16 11.7 0.1 2.1 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type DivIC PF04977.10 KUM55330.1 - 0.13 11.7 2.3 0.33 10.4 1.4 1.9 2 0 0 2 2 2 0 Septum formation initiator CHDCT2 PF08074.6 KUM55330.1 - 0.19 11.4 1.4 0.47 10.1 0.2 2.1 2 1 0 2 2 2 0 CHDCT2 (NUC038) domain zf-CCHC_4 PF14392.1 KUM55330.1 - 0.19 11.3 3.1 0.28 10.8 0.9 2.1 2 0 0 2 2 2 0 Zinc knuckle HTH_psq PF05225.11 KUM55332.1 - 1.9e-09 36.9 0.1 2.7e-09 36.3 0.1 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 KUM55332.1 - 0.0013 18.6 0.2 0.002 18.0 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.8 KUM55332.1 - 0.0032 16.8 0.8 0.0041 16.4 0.1 1.7 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain SpoIIID PF12116.3 KUM55332.1 - 0.0087 15.9 0.2 0.0098 15.8 0.2 1.3 1 0 0 1 1 1 1 Stage III sporulation protein D HTH_17 PF12728.2 KUM55332.1 - 0.012 15.8 0.1 0.017 15.3 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.2 KUM55332.1 - 0.022 14.4 0.4 0.036 13.7 0.3 1.4 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.1 KUM55332.1 - 0.022 14.3 0.6 0.039 13.6 0.4 1.6 1 1 0 1 1 1 0 Homeodomain-like domain Sigma70_r4_2 PF08281.7 KUM55332.1 - 0.045 13.2 0.1 0.1 12.0 0.1 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_IclR PF09339.5 KUM55332.1 - 0.047 13.2 0.4 0.23 11.0 0.1 2.0 2 0 0 2 2 2 0 IclR helix-turn-helix domain MerR PF00376.18 KUM55332.1 - 0.058 12.9 0.1 0.17 11.4 0.1 1.8 1 0 0 1 1 1 0 MerR family regulatory protein HTH_20 PF12840.2 KUM55332.1 - 0.063 13.0 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.1 KUM55332.1 - 0.09 12.1 0.3 0.17 11.2 0.2 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MADF_DNA_bdg PF10545.4 KUM55336.1 - 0.056 13.6 0.4 0.087 13.0 0.3 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like BIR PF00653.16 KUM55337.1 - 8.2e-05 22.9 0.1 0.00015 22.1 0.0 1.4 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain APH PF01636.18 KUM55342.1 - 8.3e-13 48.6 0.0 1e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KUM55342.1 - 1e-05 25.2 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KUM55342.1 - 0.00012 21.3 0.0 0.084 12.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain EcKinase PF02958.15 KUM55342.1 - 0.00018 20.7 0.1 0.00026 20.2 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 KUM55342.1 - 0.00027 19.7 0.0 0.00085 18.0 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) Pox_ser-thr_kin PF05445.6 KUM55342.1 - 0.0098 14.7 0.1 3.3 6.4 0.0 2.1 2 0 0 2 2 2 2 Poxvirus serine/threonine protein kinase Fructosamin_kin PF03881.9 KUM55342.1 - 0.024 13.6 0.1 0.89 8.4 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase Kdo PF06293.9 KUM55342.1 - 0.051 12.6 0.0 0.15 11.1 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KUM55342.1 - 0.078 12.0 0.0 0.16 11.0 0.0 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase CDO_I PF05995.7 KUM55343.1 - 3.8e-37 127.1 0.0 4.4e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I GNVR PF13807.1 KUM55344.1 - 0.0068 16.1 0.4 1.1 9.0 0.1 2.5 1 1 1 2 2 2 2 G-rich domain on putative tyrosine kinase AFP PF02420.10 KUM55344.1 - 3.4 8.1 19.9 45 4.6 0.0 7.4 8 0 0 8 8 8 0 Insect antifreeze protein repeat DUF1822 PF08852.6 KUM55351.1 - 0.077 11.8 0.1 0.094 11.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) Nucleoporin_FG PF13634.1 KUM55352.1 - 0.034 14.3 1.9 0.043 14.0 1.3 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeat region PP-binding PF00550.20 KUM55354.1 - 3.1e-07 30.5 0.0 1.9e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KUM55354.1 - 3.7e-07 31.0 0.2 4.1e-05 24.4 0.0 2.9 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Methyltransf_23 PF13489.1 KUM55354.1 - 0.00012 21.8 0.0 0.0008 19.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KUM55354.1 - 0.00015 21.7 0.2 0.00079 19.4 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM55354.1 - 0.00029 21.4 0.0 0.0016 19.0 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM55354.1 - 0.00062 20.0 0.0 0.0016 18.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM55354.1 - 0.057 13.8 0.0 0.21 12.0 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain DUF2303 PF10065.4 KUM55354.1 - 0.098 11.5 0.0 1.5 7.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2303) AAA PF00004.24 KUM55356.1 - 6.8e-43 146.0 0.0 1.1e-42 145.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KUM55356.1 - 1.2e-07 31.5 0.0 3.2e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KUM55356.1 - 4.1e-07 30.0 0.0 7.7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KUM55356.1 - 8.2e-06 25.9 0.1 3.5e-05 23.8 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KUM55356.1 - 1.3e-05 25.3 0.1 0.00076 19.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KUM55356.1 - 0.00015 21.4 0.1 0.00032 20.3 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KUM55356.1 - 0.00023 21.9 0.0 0.00057 20.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KUM55356.1 - 0.00076 18.5 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KUM55356.1 - 0.0013 18.1 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 KUM55356.1 - 0.0035 17.2 0.0 0.0057 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KUM55356.1 - 0.0037 16.3 0.0 0.0068 15.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 KUM55356.1 - 0.005 16.7 0.0 0.0099 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KUM55356.1 - 0.0053 15.5 0.0 0.01 14.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus KaiC PF06745.8 KUM55356.1 - 0.0064 15.6 0.1 0.02 14.0 0.0 1.8 2 0 0 2 2 2 1 KaiC AAA_18 PF13238.1 KUM55356.1 - 0.0079 16.5 0.0 0.033 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KUM55356.1 - 0.012 14.8 0.1 0.028 13.5 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 KUM55356.1 - 0.013 15.1 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KUM55356.1 - 0.013 15.0 0.0 0.042 13.4 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KUM55356.1 - 0.021 14.0 0.0 0.069 12.3 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.1 KUM55356.1 - 0.03 13.7 0.1 0.11 11.8 0.0 1.8 1 1 0 2 2 2 0 AAA domain DUF2072 PF09845.4 KUM55356.1 - 0.031 14.2 0.1 0.071 13.0 0.1 1.6 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) DUF815 PF05673.8 KUM55356.1 - 0.045 12.6 0.0 0.081 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 KUM55356.1 - 0.05 13.0 0.0 0.23 10.9 0.0 2.0 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_helicase PF00910.17 KUM55356.1 - 0.055 13.6 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 KUM55356.1 - 0.056 13.4 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Histone PF00125.19 KUM55356.1 - 0.11 12.6 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TPR_12 PF13424.1 KUM55358.1 - 5.4e-86 282.5 11.7 3.9e-22 77.9 0.3 4.5 1 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 KUM55358.1 - 2.5e-75 246.4 25.6 3.2e-14 52.2 0.2 7.5 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 KUM55358.1 - 2.7e-32 109.0 0.3 6.5e-05 22.3 0.0 6.2 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.1 KUM55358.1 - 2.8e-31 104.7 10.2 7.9e-07 28.4 0.1 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.1 KUM55358.1 - 6e-25 86.6 1.1 2e-08 33.7 0.1 3.7 3 1 0 3 3 3 3 TPR repeat TPR_2 PF07719.12 KUM55358.1 - 1.3e-17 62.1 6.7 0.015 15.2 0.1 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 KUM55358.1 - 2.5e-17 61.5 0.7 0.09 13.0 0.0 5.8 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 KUM55358.1 - 9.1e-17 61.2 2.5 7.4e-06 26.5 0.1 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat Rab5-bind PF09311.6 KUM55358.1 - 4.6e-13 49.4 5.8 0.0005 20.0 0.1 5.2 1 1 4 5 5 5 4 Rabaptin-like protein TPR_8 PF13181.1 KUM55358.1 - 3.4e-12 45.1 6.4 0.43 10.4 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 KUM55358.1 - 3.2e-11 42.8 11.3 0.047 14.3 0.1 5.7 3 2 3 6 6 6 4 Tetratricopeptide repeat Apc3 PF12895.2 KUM55358.1 - 6.7e-09 35.7 1.8 0.0065 16.5 0.1 3.9 1 1 4 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KUM55358.1 - 1.4e-08 34.8 1.4 0.028 14.7 0.2 3.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_4 PF07721.9 KUM55358.1 - 3.4e-08 33.1 0.5 10 6.8 0.0 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF1925 PF09094.6 KUM55358.1 - 6.2e-08 32.5 6.2 1.5 8.8 0.0 5.5 2 2 3 5 5 5 2 Domain of unknown function (DUF1925) PPR PF01535.15 KUM55358.1 - 2.7e-06 26.9 1.7 0.089 12.8 0.0 5.1 6 0 0 6 6 5 1 PPR repeat Atu4866 PF11512.3 KUM55358.1 - 8e-06 25.5 5.6 1.3 8.8 0.0 4.9 4 1 1 5 5 5 2 Agrobacterium tumefaciens protein Atu4866 nec1 PF10379.4 KUM55358.1 - 0.00014 21.2 0.0 3.1 7.0 0.0 4.1 1 1 4 5 5 5 1 Virulence protein nec1 Tcf25 PF04910.9 KUM55358.1 - 0.00023 20.2 0.1 0.42 9.5 0.0 3.2 2 1 1 3 3 3 1 Transcriptional repressor TCF25 DUF3366 PF11846.3 KUM55358.1 - 0.00036 20.4 1.3 6.8 6.5 0.0 3.6 2 2 2 4 4 4 0 Domain of unknown function (DUF3366) TPR_5 PF12688.2 KUM55358.1 - 0.00045 20.2 5.5 0.0052 16.8 0.5 3.3 2 1 1 3 3 3 1 Tetratrico peptide repeat TPR_3 PF07720.7 KUM55358.1 - 0.00053 19.7 0.4 44 4.0 0.0 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat FTCD PF02971.9 KUM55358.1 - 0.0011 18.6 0.4 11 5.6 0.0 4.4 2 1 3 5 5 5 0 Formiminotransferase domain MIT PF04212.13 KUM55358.1 - 0.0016 18.2 6.2 11 5.9 0.1 4.7 4 1 2 6 6 5 0 MIT (microtubule interacting and transport) domain PAS_4 PF08448.5 KUM55358.1 - 0.0028 17.6 1.7 1.9 8.5 0.1 3.5 1 1 4 5 5 5 2 PAS fold ETF_QO PF05187.8 KUM55358.1 - 0.0068 16.3 0.8 40 4.2 0.0 4.5 1 1 5 6 6 6 0 Electron transfer flavoprotein-ubiquinone oxidoreductase Coatomer_E PF04733.9 KUM55358.1 - 0.033 13.3 3.3 11 5.1 0.1 3.3 1 1 3 4 4 4 0 Coatomer epsilon subunit DUF1887 PF09002.6 KUM55358.1 - 0.041 12.3 1.3 2.2 6.6 0.0 2.6 1 1 1 3 3 3 0 Domain of unknown function (DUF1887) Mad3_BUB1_I PF08311.7 KUM55358.1 - 0.18 11.6 0.9 72 3.1 0.0 3.5 4 0 0 4 4 4 0 Mad3/BUB1 homology region 1 TPR_6 PF13174.1 KUM55358.1 - 0.2 12.1 5.0 89 3.8 0.0 5.4 5 1 0 5 5 5 0 Tetratricopeptide repeat DUF1470 PF07336.6 KUM55358.1 - 2.5 8.4 6.4 49 4.2 0.3 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1470) Mg_chelatase_2 PF13335.1 KUM55358.1 - 3.2 8.1 6.9 24 5.4 0.2 3.5 2 2 2 4 4 4 0 Magnesium chelatase, subunit ChlI rve PF00665.21 KUM55359.1 - 1.4e-13 50.9 0.0 1.7e-13 50.7 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain Thiolase_N PF00108.18 KUM55360.1 - 2.1e-62 210.4 0.0 2.5e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 KUM55360.1 - 0.0019 17.7 0.6 0.0034 16.8 0.1 1.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain RNase_H PF00075.19 KUM55361.1 - 5.5e-07 29.9 0.0 8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 RNase H 7TM_GPCR_Sri PF10327.4 KUM55363.1 - 0.04 12.8 0.1 0.051 12.5 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri Pkinase PF00069.20 KUM55368.1 - 1.6e-25 89.7 0.0 3.4e-25 88.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM55368.1 - 7.1e-05 22.0 0.5 0.044 12.8 0.0 2.4 3 0 0 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.17 KUM55368.1 - 0.087 12.1 0.1 0.18 11.1 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Coatomer_E PF04733.9 KUM55369.1 - 4.1e-58 196.8 3.5 4.7e-58 196.6 2.4 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_14 PF13428.1 KUM55369.1 - 7.9e-10 38.4 15.8 0.0018 18.7 0.0 5.8 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KUM55369.1 - 1.2e-09 38.3 19.9 0.00014 22.1 2.8 4.6 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 KUM55369.1 - 1.5e-08 35.0 17.2 4.6e-05 23.9 2.3 4.4 4 2 2 6 6 4 3 Tetratricopeptide repeat Apc3 PF12895.2 KUM55369.1 - 2.7e-07 30.6 1.4 0.0003 20.8 0.4 3.6 2 1 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KUM55369.1 - 2.6e-06 27.5 4.7 0.01 16.2 0.1 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KUM55369.1 - 6.8e-06 25.6 9.6 0.018 14.8 0.0 5.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_4 PF07721.9 KUM55369.1 - 4.7e-05 23.4 17.3 0.49 10.9 0.2 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 KUM55369.1 - 0.00034 20.2 6.2 0.37 10.4 1.0 3.7 2 1 2 4 4 4 3 TPR repeat TPR_9 PF13371.1 KUM55369.1 - 0.0047 16.7 4.8 1.9 8.4 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KUM55369.1 - 0.009 15.5 4.3 0.81 9.3 0.0 4.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 KUM55369.1 - 0.011 15.8 1.6 21 5.6 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 KUM55369.1 - 0.047 13.6 8.7 3.1 7.8 2.0 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF1874 PF08960.5 KUM55369.1 - 0.11 12.2 0.1 0.29 10.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1874) TPR_20 PF14561.1 KUM55369.1 - 0.16 12.1 12.3 0.9 9.7 1.1 3.7 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_5 PF12688.2 KUM55369.1 - 0.21 11.6 5.0 2.3 8.2 0.1 3.2 2 1 2 4 4 4 0 Tetratrico peptide repeat TPR_10 PF13374.1 KUM55369.1 - 4.4 7.3 12.9 9.7 6.2 0.5 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.8 KUM55370.1 - 9.2e-10 38.4 0.0 1.1e-09 38.1 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KUM55370.1 - 4.2e-07 28.9 0.0 5e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) DUF3194 PF11419.3 KUM55371.1 - 3.6 7.8 12.4 8.3 6.7 8.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3194) Peptidase_S10 PF00450.17 KUM55372.1 - 3.7e-108 362.3 1.6 4.5e-108 362.0 1.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase rve PF00665.21 KUM55373.1 - 5.1e-21 75.0 0.1 1.4e-20 73.5 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 KUM55373.1 - 3.8e-08 32.8 0.7 8.6e-08 31.7 0.5 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 KUM55373.1 - 2.1e-05 23.8 0.4 4.6e-05 22.7 0.3 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Metallophos PF00149.23 KUM55378.1 - 1.4e-41 142.1 0.2 1.8e-41 141.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2593 PF10767.4 KUM55379.1 - 0.41 10.3 2.6 0.5 10.0 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2593) Lys PF00062.15 KUM55380.1 - 0.069 13.1 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family DUF4081 PF13312.1 KUM55388.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4081) Asp_protease_2 PF13650.1 KUM55389.1 - 9.5e-06 26.0 0.1 4.6e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease DUF2097 PF09870.4 KUM55389.1 - 0.016 15.2 0.1 0.039 14.0 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2097) DUF848 PF05852.6 KUM55389.1 - 0.061 13.1 1.2 0.15 11.8 0.9 1.7 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Med4 PF10018.4 KUM55390.1 - 3.1e-45 153.8 0.5 5.3e-45 153.1 0.4 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Kinesin-relat_1 PF12711.2 KUM55390.1 - 0.043 14.2 0.0 0.095 13.1 0.0 1.5 1 0 0 1 1 1 0 Kinesin motor Ank_2 PF12796.2 KUM55392.1 - 1.1e-66 221.1 6.9 1.7e-18 66.7 0.1 4.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KUM55392.1 - 1.7e-42 141.1 1.7 1e-05 25.0 0.0 7.2 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 KUM55392.1 - 6.5e-37 125.2 0.0 4.1e-11 43.0 0.0 5.6 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM55392.1 - 8.8e-37 121.4 0.9 0.00026 20.9 0.0 7.4 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.1 KUM55392.1 - 3.8e-18 65.0 4.9 1.1e-07 31.8 0.0 5.6 2 1 4 6 6 6 4 Ankyrin repeats (many copies) F-box-like PF12937.2 KUM55392.1 - 2.6e-06 27.0 0.4 5e-06 26.1 0.3 1.5 1 0 0 1 1 1 1 F-box-like DUF4388 PF14332.1 KUM55392.1 - 0.015 15.1 0.1 3.1 7.7 0.1 3.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4388) Phosphoprotein PF00922.12 KUM55396.1 - 1.5 8.0 4.2 1.7 7.7 2.9 1.0 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein MFS_1 PF07690.11 KUM55400.1 - 1.7e-36 125.6 24.8 1.4e-35 122.6 17.8 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM55400.1 - 1.5e-11 43.5 11.8 5.2e-06 25.3 3.7 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter Acetyltransf_1 PF00583.19 KUM55401.1 - 5.7e-17 61.5 0.0 8.9e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KUM55401.1 - 2.6e-12 46.8 0.1 3.3e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KUM55401.1 - 1.1e-06 28.3 0.0 1.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 KUM55401.1 - 1.9e-06 28.0 0.0 2.4e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KUM55401.1 - 2.3e-06 27.6 0.0 3.2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KUM55401.1 - 0.001 19.0 0.0 0.0012 18.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KUM55401.1 - 0.0056 16.5 0.0 0.0085 15.9 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 KUM55401.1 - 0.0078 16.1 0.0 0.013 15.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Cyt-b5 PF00173.23 KUM55405.1 - 3e-09 36.5 0.0 3.8e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RRM_1 PF00076.17 KUM55406.1 - 5.4e-58 192.5 0.1 1.2e-19 69.6 0.1 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM55406.1 - 4.6e-41 138.6 0.1 3.4e-13 49.3 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM55406.1 - 3.1e-23 81.3 0.1 8.4e-10 38.3 0.0 4.1 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KUM55406.1 - 0.013 15.1 0.3 0.31 10.8 0.0 3.4 3 0 0 3 3 3 0 Limkain b1 Atg14 PF10186.4 KUM55406.1 - 0.74 8.7 5.4 0.073 11.9 0.5 1.7 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 FAD_binding_4 PF01565.18 KUM55407.1 - 1.1e-10 41.1 1.9 3.7e-10 39.4 1.3 2.0 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KUM55407.1 - 2.9e-10 39.8 1.2 6.1e-10 38.8 0.8 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KUM55407.1 - 0.0023 17.1 0.1 0.0036 16.4 0.1 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding AAA_12 PF13087.1 KUM55408.1 - 3.5e-17 62.4 0.0 4.1e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 KUM55408.1 - 8.2e-05 22.7 0.0 0.00017 21.7 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 KUM55408.1 - 0.0011 18.5 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 KUM55409.1 - 5.3e-09 35.9 0.0 9.4e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KUM55409.1 - 2.9e-05 23.7 0.1 6.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Glyco_transf_90 PF05686.7 KUM55412.1 - 3.3e-17 62.2 3.6 1.4e-15 56.9 0.8 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 90 Methyltransf_23 PF13489.1 KUM55417.1 - 5e-23 81.5 0.0 8e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM55417.1 - 1.5e-10 40.8 0.0 1.2e-09 37.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM55417.1 - 5.5e-10 39.8 0.0 7e-09 36.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM55417.1 - 7.9e-05 23.0 0.0 0.0018 18.7 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 KUM55417.1 - 0.00011 21.3 0.0 0.00085 18.4 0.0 2.2 2 1 0 2 2 2 1 Putative methyltransferase Methyltransf_11 PF08241.7 KUM55417.1 - 0.00021 21.7 0.0 0.00041 20.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KUM55417.1 - 0.01 15.8 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.9 KUM55417.1 - 0.012 15.0 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.1 KUM55417.1 - 0.017 15.4 0.0 0.036 14.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 KUM55417.1 - 0.02 14.9 0.0 0.1 12.6 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 KUM55417.1 - 0.027 13.9 0.0 0.081 12.3 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase PrmA PF06325.8 KUM55417.1 - 0.07 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 KUM55417.1 - 0.19 11.2 0.0 0.57 9.6 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TPR_12 PF13424.1 KUM55419.1 - 1.8e-114 373.8 13.3 2.6e-20 72.1 0.0 7.6 2 2 7 9 9 9 9 Tetratricopeptide repeat TPR_10 PF13374.1 KUM55419.1 - 3e-108 351.0 0.0 1.2e-13 50.4 0.0 10.2 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_7 PF13176.1 KUM55419.1 - 9.4e-44 143.7 11.8 0.00036 20.0 0.0 10.2 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_1 PF00515.23 KUM55419.1 - 9.5e-30 100.9 6.2 0.0046 16.5 0.0 10.2 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 KUM55419.1 - 3.2e-29 98.4 5.9 0.017 15.0 0.0 10.0 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_17 PF13431.1 KUM55419.1 - 6.9e-27 91.3 3.5 0.33 11.2 0.0 10.3 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_11 PF13414.1 KUM55419.1 - 8.7e-27 92.5 0.4 4.8e-06 26.1 0.0 7.3 4 2 1 7 7 7 5 TPR repeat TPR_4 PF07721.9 KUM55419.1 - 5.3e-24 82.1 11.3 0.013 15.8 0.2 9.2 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.1 KUM55419.1 - 1.4e-21 74.6 10.0 0.24 11.2 0.0 9.9 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.1 KUM55419.1 - 5.7e-20 71.4 3.8 8.3e-05 22.8 0.0 8.8 5 2 5 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 KUM55419.1 - 6.4e-20 69.8 7.1 0.069 13.8 0.0 9.7 8 1 2 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.1 KUM55419.1 - 7.4e-20 71.0 0.2 0.006 17.2 0.0 7.1 3 2 6 9 9 9 5 Tetratricopeptide repeat PPR PF01535.15 KUM55419.1 - 2.5e-13 49.0 0.4 0.28 11.2 0.0 7.9 8 0 0 8 8 8 1 PPR repeat Apc3 PF12895.2 KUM55419.1 - 1.5e-12 47.4 0.4 0.00099 19.2 0.0 5.9 2 2 5 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 DUF814 PF05670.8 KUM55419.1 - 7.6e-11 41.7 0.6 1.7 8.5 0.0 7.7 1 1 6 7 7 7 1 Domain of unknown function (DUF814) PPR_3 PF13812.1 KUM55419.1 - 1.5e-09 37.3 2.3 8.3 6.9 0.0 8.6 10 0 0 10 10 8 0 Pentatricopeptide repeat domain TPR_20 PF14561.1 KUM55419.1 - 1.1e-08 35.0 3.3 1.6 8.9 0.0 7.6 3 2 6 9 9 9 1 Tetratricopeptide repeat DUF4074 PF13293.1 KUM55419.1 - 2.1e-07 31.0 7.1 23 5.2 0.0 8.8 10 0 0 10 10 9 0 Domain of unknown function (DUF4074) TPR_6 PF13174.1 KUM55419.1 - 6.1e-07 29.4 18.8 3.6 8.2 0.0 9.1 9 0 0 9 9 9 2 Tetratricopeptide repeat SNAP PF14938.1 KUM55419.1 - 2.6e-05 23.5 0.3 0.45 9.6 0.0 4.4 1 1 3 4 4 4 1 Soluble NSF attachment protein, SNAP PPR_2 PF13041.1 KUM55419.1 - 0.00014 21.7 2.7 46 4.0 0.0 7.0 8 0 0 8 8 8 0 PPR repeat family DUF2518 PF10726.4 KUM55419.1 - 0.0005 19.6 0.5 6.7 6.2 0.0 5.1 2 2 2 6 6 6 0 Protein of function (DUF2518) Rapsyn_N PF10579.4 KUM55419.1 - 0.00077 19.2 0.3 17 5.3 0.0 4.6 4 1 1 5 5 5 0 Rapsyn N-terminal myristoylation and linker region YfdX PF10938.3 KUM55419.1 - 0.0037 16.9 0.6 0.79 9.3 0.1 2.9 3 0 0 3 3 2 1 YfdX protein DUF4054 PF13262.1 KUM55419.1 - 0.0037 17.4 0.6 36 4.6 0.0 5.4 6 0 0 6 6 6 0 Protein of unknown function (DUF4054) Cytochrom_B562 PF07361.6 KUM55419.1 - 0.004 17.5 6.2 3 8.2 0.2 4.4 5 1 0 5 5 3 1 Cytochrome b562 SLT_2 PF13406.1 KUM55419.1 - 0.01 14.7 0.2 1.6 7.5 0.0 3.6 2 1 0 3 3 3 0 Transglycosylase SLT domain Foie-gras_1 PF11817.3 KUM55419.1 - 0.06 12.8 3.0 3.6 6.9 0.0 4.4 6 0 0 6 6 6 0 Foie gras liver health family 1 Transposase_28 PF04195.7 KUM55419.1 - 0.13 11.5 0.0 9.5 5.4 0.0 2.2 2 0 0 2 2 2 0 Putative gypsy type transposon DUF4363 PF14276.1 KUM55419.1 - 0.19 11.4 4.5 7.6 6.2 0.0 4.6 5 1 1 6 6 5 0 Domain of unknown function (DUF4363) Myb_DNA-bind_6 PF13921.1 KUM55422.1 - 0.00057 19.9 0.1 0.0012 18.9 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain APH PF01636.18 KUM55423.1 - 3.3e-09 36.8 0.0 5.9e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KUM55423.1 - 2.7e-08 33.3 0.1 6e-08 32.1 0.0 1.5 2 0 0 2 2 2 1 Ecdysteroid kinase Choline_kinase PF01633.15 KUM55423.1 - 0.00011 21.8 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 KUM55423.1 - 0.02 13.8 0.1 0.049 12.6 0.1 1.8 1 1 0 1 1 1 0 Fructosamine kinase DUF1679 PF07914.6 KUM55423.1 - 0.057 12.0 0.0 0.08 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Aegerolysin PF06355.8 KUM55424.1 - 2.5e-38 130.8 0.3 3e-38 130.6 0.2 1.0 1 0 0 1 1 1 1 Aegerolysin RVT_1 PF00078.22 KUM55425.1 - 1.5e-13 50.6 0.0 6e-09 35.5 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) TraF PF13728.1 KUM55425.1 - 0.049 13.1 0.1 0.077 12.4 0.1 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein SLH PF00395.15 KUM55425.1 - 0.17 11.6 1.1 18 5.1 0.1 2.6 2 0 0 2 2 2 0 S-layer homology domain Glyco_hydro_32N PF00251.15 KUM55426.1 - 1.3e-87 294.0 4.7 2.8e-71 240.3 0.3 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 KUM55426.1 - 1.9e-17 63.4 0.1 4.1e-17 62.3 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR_2 PF13088.1 KUM55426.1 - 0.00087 18.6 0.5 0.0027 17.0 0.3 1.8 1 1 0 1 1 1 1 BNR repeat-like domain MFS_1 PF07690.11 KUM55429.1 - 1.3e-32 112.8 54.9 1.3e-32 112.8 38.1 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM55429.1 - 5.8e-22 77.6 20.7 5.8e-22 77.6 14.3 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KUM55429.1 - 1.7e-11 43.3 5.9 1.7e-11 43.3 4.1 2.5 4 0 0 4 4 4 1 Sugar (and other) transporter zf-CCHC PF00098.18 KUM55430.1 - 0.13 12.2 7.2 0.085 12.8 0.8 2.7 2 0 0 2 2 2 0 Zinc knuckle Exo_endo_phos_2 PF14529.1 KUM55431.1 - 1.8e-20 72.7 0.2 5.2e-20 71.2 0.1 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 KUM55431.1 - 7e-06 26.1 0.1 1.2e-05 25.3 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Cupin_2 PF07883.6 KUM55432.1 - 3.6e-07 29.5 0.0 7e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 KUM55432.1 - 0.0063 16.1 0.0 0.0089 15.6 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 KUM55432.1 - 0.041 13.2 0.0 0.08 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) ADH_zinc_N PF00107.21 KUM55433.1 - 1.2e-25 89.5 0.1 2e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KUM55433.1 - 1.5e-19 71.1 0.0 4.3e-19 69.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM55433.1 - 1.1e-10 41.1 0.0 2.5e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 KUM55433.1 - 0.084 12.4 0.6 0.97 8.9 0.1 2.0 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF3716 PF12511.3 KUM55435.1 - 6.4e-10 38.4 0.1 9.7e-10 37.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) RHIM PF12721.2 KUM55436.1 - 0.023 15.1 3.7 1.8 8.9 0.3 2.3 1 1 1 2 2 2 0 RIP homotypic interaction motif Myb_DNA-bind_6 PF13921.1 KUM55437.1 - 0.0083 16.2 0.7 0.02 15.0 0.5 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain APH PF01636.18 KUM55440.1 - 2.5e-16 60.1 0.0 5.7e-16 58.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KUM55440.1 - 7.9e-07 28.8 0.0 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KUM55440.1 - 0.0093 15.1 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 KUM55440.1 - 0.022 14.1 0.0 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 RIO1 family EcKinase PF02958.15 KUM55440.1 - 0.063 12.4 0.1 0.096 11.8 0.1 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DUF3435 PF11917.3 KUM55441.1 - 1.6e-20 73.2 0.3 2.1e-20 72.8 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) p450 PF00067.17 KUM55442.1 - 1.5e-34 119.2 0.0 6.2e-34 117.3 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Peripla_BP_2 PF01497.13 KUM55442.1 - 0.091 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Brevenin PF03032.10 KUM55444.1 - 0.072 12.9 1.8 0.13 12.1 1.2 1.4 1 0 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family UQ_con PF00179.21 KUM55446.1 - 2.4e-47 159.8 0.0 3e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KUM55446.1 - 0.00051 19.9 0.3 0.00077 19.3 0.2 1.5 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 KUM55446.1 - 0.00059 19.5 0.0 0.00089 18.9 0.0 1.4 1 0 0 1 1 1 1 UEV domain Prok-E2_B PF14461.1 KUM55446.1 - 0.00072 19.3 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RNase_H PF00075.19 KUM55447.1 - 2.6e-09 37.4 0.0 4.4e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 KUM55447.1 - 0.00037 20.2 0.0 0.0013 18.4 0.0 2.0 1 1 0 1 1 1 1 Reverse transcriptase-like Glyco_hydro_18 PF00704.23 KUM55448.1 - 1e-21 77.7 0.4 9.7e-21 74.5 0.0 2.0 1 1 0 2 2 2 1 Glycosyl hydrolases family 18 Herpes_BLLF1 PF05109.8 KUM55448.1 - 0.0014 16.6 18.9 0.0016 16.4 13.1 1.2 1 0 0 1 1 1 1 Herpes virus major outer envelope glycoprotein (BLLF1) GWT1 PF06423.7 KUM55450.1 - 0.027 14.5 5.8 0.053 13.6 3.8 1.8 1 1 0 1 1 1 0 GWT1 DUF3669 PF12417.3 KUM55451.1 - 5.9e-21 73.9 0.0 1.3e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 Zinc finger protein HALZ PF02183.13 KUM55452.1 - 3.1e-05 23.6 2.4 5.6e-05 22.7 1.7 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper GAS PF13851.1 KUM55452.1 - 0.0018 17.5 0.8 0.0021 17.2 0.6 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding UPF0242 PF06785.6 KUM55452.1 - 0.0021 16.8 0.7 0.0024 16.5 0.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) SipA PF09052.5 KUM55452.1 - 0.0037 15.7 0.3 0.0038 15.7 0.2 1.2 1 0 0 1 1 1 1 Salmonella invasion protein A TMF_TATA_bd PF12325.3 KUM55452.1 - 0.0077 15.9 1.2 0.011 15.5 0.9 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DivIC PF04977.10 KUM55452.1 - 0.0098 15.3 1.2 0.016 14.7 0.8 1.3 1 0 0 1 1 1 1 Septum formation initiator Mei5 PF10376.4 KUM55452.1 - 0.011 15.2 0.4 0.014 14.9 0.3 1.2 1 0 0 1 1 1 0 Double-strand recombination repair protein bZIP_1 PF00170.16 KUM55452.1 - 0.014 15.3 1.3 0.021 14.7 0.9 1.4 1 0 0 1 1 1 0 bZIP transcription factor HAP1_N PF04849.8 KUM55452.1 - 0.014 14.3 3.8 0.028 13.3 2.6 1.4 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Sigma70_ner PF04546.8 KUM55452.1 - 0.016 14.8 4.6 0.02 14.5 3.2 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region bZIP_2 PF07716.10 KUM55452.1 - 0.019 14.8 2.5 0.037 13.8 1.8 1.5 1 0 0 1 1 1 0 Basic region leucine zipper APG6 PF04111.7 KUM55452.1 - 0.027 13.5 1.9 0.03 13.3 1.3 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF244 PF03112.9 KUM55452.1 - 0.033 13.7 0.6 0.041 13.4 0.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF Nnf1 PF03980.9 KUM55452.1 - 0.04 13.9 0.3 0.065 13.2 0.2 1.4 1 0 0 1 1 1 0 Nnf1 Uso1_p115_C PF04871.8 KUM55452.1 - 0.041 13.8 1.9 0.057 13.3 1.3 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF342 PF03961.8 KUM55452.1 - 0.052 11.9 0.9 0.057 11.8 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4140 PF13600.1 KUM55452.1 - 0.12 12.8 0.5 0.17 12.3 0.3 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) TSC22 PF01166.13 KUM55452.1 - 0.12 12.3 2.5 0.2 11.6 1.2 1.7 1 1 1 2 2 2 0 TSC-22/dip/bun family IncA PF04156.9 KUM55452.1 - 0.26 10.8 1.2 0.31 10.6 0.9 1.1 1 0 0 1 1 1 0 IncA protein DUF3534 PF12053.3 KUM55452.1 - 6.2 6.6 6.0 1.8 8.4 1.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3534) adh_short PF00106.20 KUM55453.1 - 9.2e-13 48.4 1.0 1e-12 48.2 0.7 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM55453.1 - 8.8e-09 35.4 0.1 1e-08 35.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM55453.1 - 3.4e-07 30.0 0.2 3.9e-07 29.9 0.2 1.0 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 KUM55453.1 - 0.0027 16.8 0.0 0.0032 16.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KUM55453.1 - 0.01 15.8 0.2 0.013 15.5 0.2 1.1 1 0 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 KUM55453.1 - 0.028 14.0 0.4 0.032 13.8 0.3 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KUM55453.1 - 0.091 13.0 0.1 0.12 12.6 0.1 1.1 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.22 KUM55453.1 - 0.11 12.8 0.3 0.16 12.3 0.2 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Eno-Rase_NADH_b PF12242.3 KUM55453.1 - 1 9.1 3.2 1.2 9.0 1.6 1.5 1 1 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FGGY_C PF02782.11 KUM55454.1 - 1.2e-47 162.1 0.8 1.6e-47 161.6 0.5 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KUM55454.1 - 8.9e-23 80.8 0.1 1e-21 77.4 0.1 2.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 KUM55454.1 - 0.00048 19.4 0.1 0.0058 15.9 0.0 2.5 2 1 1 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family RVT_1 PF00078.22 KUM55456.1 - 2.2e-29 102.3 0.0 3.3e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 KUM55456.1 - 3.1e-15 55.8 0.0 2.2e-14 53.0 0.0 2.5 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 KUM55456.1 - 2e-14 54.0 0.5 3e-13 50.2 0.3 2.3 1 1 0 1 1 1 1 RNase H Exo_endo_phos PF03372.18 KUM55456.1 - 3.3e-10 40.3 0.1 6.4e-10 39.3 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_3 PF13456.1 KUM55456.1 - 0.00012 21.7 0.2 0.0056 16.4 0.0 2.6 1 1 1 2 2 2 1 Reverse transcriptase-like C2 PF00168.25 KUM55460.1 - 4.6e-09 35.9 0.0 9.6e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain Fungal_trans PF04082.13 KUM55462.1 - 2e-13 49.8 0.3 3.4e-13 49.0 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM55462.1 - 2.3e-07 30.6 13.3 4e-07 29.8 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KUM55463.1 - 9.6e-39 133.0 55.8 9.6e-39 133.0 38.7 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM55463.1 - 3.8e-11 41.8 27.9 3.9e-11 41.8 18.6 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4448 PF14610.1 KUM55463.1 - 0.11 11.9 1.4 4.5 6.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) Fungal_trans_2 PF11951.3 KUM55464.1 - 1.9e-62 211.0 0.6 2.6e-62 210.6 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM55464.1 - 1.8e-09 37.3 11.1 2.7e-09 36.8 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 KUM55464.1 - 0.39 10.5 6.8 1 9.2 4.7 1.7 1 0 0 1 1 1 0 AT hook motif Form_Nir_trans PF01226.12 KUM55465.1 - 1.3e-10 40.6 0.1 2e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Formate/nitrite transporter TauD PF02668.11 KUM55466.1 - 2.4e-25 89.7 0.1 6.7e-25 88.2 0.0 1.6 1 1 1 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family TSSC4 PF15264.1 KUM55466.1 - 0.053 13.9 0.4 0.093 13.1 0.3 1.3 1 0 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 Fungal_trans PF04082.13 KUM55467.1 - 5.5e-11 41.8 1.0 2.6e-10 39.6 0.7 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KUM55467.1 - 1.7e-07 31.1 11.2 0.0028 17.9 2.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KUM55467.1 - 0.0009 19.4 2.0 0.0009 19.4 1.4 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KUM55467.1 - 0.0011 19.1 15.1 0.017 15.4 2.3 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger HWE_HK PF07536.9 KUM55467.1 - 0.12 12.8 0.7 0.28 11.6 0.5 1.7 1 0 0 1 1 1 0 HWE histidine kinase Telomere_Sde2 PF13019.1 KUM55468.1 - 5.9e-65 217.8 0.8 9.4e-65 217.2 0.6 1.3 1 0 0 1 1 1 1 Telomere stability and silencing LacI PF00356.16 KUM55468.1 - 0.017 14.7 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family MMR_HSR1 PF01926.18 KUM55469.1 - 6.4e-07 29.3 0.0 5e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATPase-cat_bd PF12156.3 KUM55469.1 - 0.0067 16.9 0.1 0.015 15.8 0.1 1.5 1 0 0 1 1 1 1 Putative metal-binding domain of cation transport ATPase DUF258 PF03193.11 KUM55469.1 - 0.01 14.9 0.0 0.041 13.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Miro PF08477.8 KUM55469.1 - 0.06 13.8 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 KUM55469.1 - 0.086 12.6 0.0 0.77 9.5 0.0 2.4 2 0 0 2 2 2 0 Dynamin family Amidohydro_1 PF01979.15 KUM55470.1 - 3.1e-24 86.2 0.0 6.8e-11 42.4 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KUM55470.1 - 4.4e-14 52.0 0.3 1.9e-13 50.0 0.2 2.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KUM55470.1 - 1.4e-09 38.4 0.1 0.0011 19.1 0.0 2.6 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 KUM55470.1 - 6.5e-06 25.6 0.1 0.00046 19.5 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family HTH_AsnC-type PF13404.1 KUM55470.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Fungal_trans PF04082.13 KUM55471.1 - 0.00018 20.4 0.5 0.00018 20.4 0.3 2.2 1 1 1 2 2 2 1 Fungal specific transcription factor domain HNH_2 PF13391.1 KUM55472.1 - 1e-07 31.5 0.1 2.4e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease WD40 PF00400.27 KUM55473.1 - 4.6e-07 29.4 1.6 0.019 14.8 0.0 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF2583 PF10762.4 KUM55473.1 - 1.6 8.9 4.4 0.99 9.5 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) DUF946 PF06101.6 KUM55474.1 - 7e-13 47.4 0.8 7e-13 47.4 0.6 1.9 2 0 0 2 2 2 1 Plant protein of unknown function (DUF946) NPP1 PF05630.6 KUM55474.1 - 0.017 14.8 0.2 0.03 14.0 0.1 1.3 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) DUF1302 PF06980.6 KUM55474.1 - 0.076 11.5 0.3 0.13 10.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1302) Plasmid_stabil PF05016.9 KUM55478.1 - 0.086 13.2 0.0 0.23 11.8 0.0 1.6 2 0 0 2 2 2 0 Plasmid stabilisation system protein p450 PF00067.17 KUM55480.1 - 1.9e-69 234.4 0.0 2.4e-69 234.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CS PF04969.11 KUM55482.1 - 2.2e-17 63.3 0.0 3.7e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 CS domain HALZ PF02183.13 KUM55483.1 - 0.00066 19.3 1.7 0.0011 18.5 1.2 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper Rab5-bind PF09311.6 KUM55483.1 - 0.12 12.2 1.0 0.18 11.6 0.7 1.2 1 0 0 1 1 1 0 Rabaptin-like protein DivIC PF04977.10 KUM55483.1 - 0.25 10.8 2.9 0.33 10.4 2.0 1.4 1 1 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.10 KUM55483.1 - 0.35 10.7 4.0 0.56 10.0 2.8 1.4 1 0 0 1 1 1 0 Basic region leucine zipper DUF3701 PF12482.3 KUM55484.1 - 0.052 13.2 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 Phage integrase protein PS_Dcarbxylase PF02666.10 KUM55485.1 - 1.2e-16 60.6 0.1 1.4e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase GMC_oxred_C PF05199.8 KUM55486.1 - 1.5e-21 77.1 0.0 1.7e-21 77.0 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KUM55487.1 - 5.1e-34 117.7 0.0 5.9e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KUM55487.1 - 0.00072 18.5 0.0 0.00097 18.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KUM55487.1 - 0.003 17.5 0.0 0.0066 16.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KUM55487.1 - 0.0031 16.6 0.1 0.0048 16.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KUM55487.1 - 0.0066 15.3 0.3 0.0098 14.8 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KUM55487.1 - 0.0075 16.1 0.0 0.014 15.2 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KUM55487.1 - 0.032 13.0 1.7 0.056 12.2 0.6 1.7 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.9 KUM55487.1 - 0.11 11.0 0.1 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.13 KUM55487.1 - 0.13 12.2 0.2 0.29 11.1 0.1 1.7 2 0 0 2 2 2 0 TrkA-N domain GMC_oxred_C PF05199.8 KUM55488.1 - 3.6e-08 33.8 0.0 4.9e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KUM55488.1 - 3.2e-06 26.5 0.7 4.1e-06 26.1 0.5 1.1 1 0 0 1 1 1 1 GMC oxidoreductase ChW PF07538.6 KUM55493.1 - 0.73 9.4 0.2 0.73 9.4 0.2 2.3 2 0 0 2 2 2 0 Clostridial hydrophobic W Epimerase PF01370.16 KUM55496.1 - 2.7e-07 30.2 0.0 8.9e-05 22.0 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KUM55496.1 - 7.9e-05 22.0 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KUM55496.1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding NAD_binding_4 PF07993.7 KUM55496.1 - 0.018 13.9 0.0 0.26 10.1 0.0 2.5 3 0 0 3 3 3 0 Male sterility protein Semialdhyde_dh PF01118.19 KUM55496.1 - 0.02 15.1 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KUM55496.1 - 0.046 12.7 0.0 0.07 12.1 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase ADH_zinc_N PF00107.21 KUM55497.1 - 1.3e-22 79.7 0.8 2.1e-22 79.0 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM55497.1 - 2.5e-13 49.7 0.1 5.9e-12 45.3 0.1 2.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KUM55497.1 - 4.6e-12 46.9 0.1 9.3e-12 45.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PS_Dcarbxylase PF02666.10 KUM55497.1 - 0.023 13.9 0.0 0.044 13.0 0.0 1.5 1 0 0 1 1 1 0 Phosphatidylserine decarboxylase Sugar_tr PF00083.19 KUM55498.1 - 8.7e-13 47.6 10.4 9.4e-13 47.5 7.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM55498.1 - 0.00017 20.4 1.3 0.00018 20.3 0.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily ICL PF00463.16 KUM55500.1 - 9.8e-189 627.9 0.0 1.1e-188 627.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KUM55500.1 - 9.2e-10 38.1 0.0 1.6e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 KUM55500.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain adh_short PF00106.20 KUM55502.1 - 2.2e-12 47.1 0.7 7.9e-12 45.4 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KUM55502.1 - 3.6e-12 46.3 0.0 1.4e-11 44.3 0.0 2.0 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.21 KUM55502.1 - 8.7e-10 38.2 0.0 2.1e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KR PF08659.5 KUM55503.1 - 1.1e-10 41.4 0.1 4.5e-10 39.4 0.0 2.0 3 0 0 3 3 3 1 KR domain PP-binding PF00550.20 KUM55503.1 - 4.7e-07 29.9 0.1 1.5e-06 28.3 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 KUM55503.1 - 2.1e-05 24.4 1.3 0.00013 21.9 0.1 2.5 2 1 1 3 3 3 1 short chain dehydrogenase DUF4262 PF14081.1 KUM55505.1 - 0.031 14.4 0.1 0.076 13.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4262) Aminotran_1_2 PF00155.16 KUM55512.1 - 5.5e-40 137.4 0.0 6.5e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HNH_2 PF13391.1 KUM55514.1 - 1.2e-05 25.0 0.0 2.9e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease ubiquitin PF00240.18 KUM55515.1 - 4.8e-136 442.3 23.5 1.1e-33 114.4 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 KUM55515.1 - 2.2e-78 257.9 21.1 4.3e-19 67.9 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KUM55515.1 - 2.6e-24 85.2 11.1 0.00015 21.9 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KUM55515.1 - 5.2e-22 78.2 1.5 0.00071 19.3 0.0 4.0 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KUM55515.1 - 5.2e-14 52.0 2.9 0.13 12.1 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KUM55515.1 - 8.1e-14 51.5 2.4 0.13 12.5 0.0 4.2 1 1 3 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 KUM55515.1 - 9.7e-11 41.5 0.0 1.5 8.8 0.0 4.9 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 KUM55515.1 - 1.6e-06 27.9 5.8 4.5 7.2 0.0 4.2 4 0 0 4 4 4 4 GLUT4 regulating protein TUG Methyltrans_RNA PF04452.9 KUM55515.1 - 5.3e-06 25.7 0.5 2 7.5 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase FlgD_ig PF13860.1 KUM55515.1 - 6.8e-05 22.5 5.3 14 5.5 0.0 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain Plexin_cytopl PF08337.7 KUM55515.1 - 0.00045 18.6 13.5 2.3 6.4 0.2 5.7 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain Big_3_3 PF13750.1 KUM55515.1 - 0.0011 18.4 0.0 48 3.3 0.0 4.0 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) ACT_4 PF13291.1 KUM55515.1 - 0.0019 18.5 0.6 1e+02 3.3 0.0 4.2 4 0 0 4 4 4 0 ACT domain DUF3861 PF12977.2 KUM55515.1 - 0.0055 16.7 5.2 53 4.0 0.0 4.4 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) CTDII PF01556.13 KUM55515.1 - 0.023 14.5 14.3 7.9 6.4 0.2 4.4 1 1 2 4 4 4 0 DnaJ C terminal domain Tash_PEST PF07708.6 KUM55515.1 - 0.026 14.4 29.1 3.5 7.7 1.2 4.4 4 0 0 4 4 4 0 Tash protein PEST motif GABP-alpha PF11620.3 KUM55515.1 - 0.037 14.0 7.8 44 4.1 0.1 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain FERM_N PF09379.5 KUM55515.1 - 0.071 13.1 12.4 42 4.2 0.1 5.9 4 4 0 4 4 4 0 FERM N-terminal domain DUF3781 PF12636.2 KUM55515.1 - 0.4 10.6 7.4 1e+02 2.9 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) Myosin_N PF02736.14 KUM55515.1 - 1.8 8.2 8.3 1e+02 2.7 0.1 4.7 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain CDC48_2 PF02933.12 KUM55515.1 - 9.3 5.9 12.2 70 3.1 0.1 4.1 4 0 0 4 4 4 0 Cell division protein 48 (CDC48), domain 2 BRAP2 PF07576.7 KUM55516.1 - 7.2e-25 86.7 0.0 1.4e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 KUM55516.1 - 1.1e-19 70.2 6.9 1.8e-19 69.6 3.8 2.1 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 KUM55516.1 - 6.2e-10 38.7 9.8 6.2e-10 38.7 6.8 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KUM55516.1 - 2.3e-05 24.0 8.2 2.3e-05 24.0 5.7 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KUM55516.1 - 0.00017 21.1 8.8 0.00017 21.1 6.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KUM55516.1 - 0.00024 21.0 9.4 0.00024 21.0 6.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KUM55516.1 - 0.00036 20.1 6.0 0.00036 20.1 4.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KUM55516.1 - 0.0011 18.6 5.4 0.0039 16.8 1.8 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 KUM55516.1 - 0.0016 18.4 5.8 0.0016 18.4 4.1 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_6 PF14835.1 KUM55516.1 - 0.0051 16.5 2.8 0.0051 16.5 2.0 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 KUM55516.1 - 0.0059 16.4 5.3 0.018 14.8 3.7 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_RING PF05883.6 KUM55516.1 - 0.071 12.9 1.6 0.16 11.7 1.1 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain FTA4 PF13093.1 KUM55516.1 - 0.076 12.4 3.4 0.14 11.6 2.3 1.3 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 TPR_MLP1_2 PF07926.7 KUM55516.1 - 0.94 9.2 9.6 1.8 8.2 6.7 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein MutS_V PF00488.16 KUM55520.1 - 7.5e-90 300.4 0.1 1.4e-89 299.5 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KUM55520.1 - 1.3e-36 126.3 0.5 3e-36 125.1 0.4 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KUM55520.1 - 5.9e-28 97.1 0.0 1.7e-27 95.6 0.0 1.9 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KUM55520.1 - 2.5e-08 34.0 0.0 9.7e-08 32.1 0.0 2.1 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 KUM55520.1 - 1.2e-05 25.4 0.7 2.9e-05 24.1 0.1 2.0 2 0 0 2 2 2 1 MutS family domain IV GST_N_3 PF13417.1 KUM55521.1 - 4.1e-11 42.9 0.0 7.3e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KUM55521.1 - 5e-09 36.0 0.0 1.2e-08 34.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KUM55521.1 - 8.3e-09 35.4 0.0 1.5e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KUM55521.1 - 3.5e-08 33.3 0.0 5.3e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KUM55521.1 - 0.0021 17.9 0.1 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TPR_10 PF13374.1 KUM55522.1 - 7.3e-96 311.7 2.3 1.8e-12 46.7 0.1 10.7 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.1 KUM55522.1 - 2.3e-67 222.9 11.3 1.5e-15 56.8 0.0 6.8 3 2 3 7 7 7 7 Tetratricopeptide repeat TPR_11 PF13414.1 KUM55522.1 - 3.5e-17 61.8 2.5 0.0021 17.6 0.0 6.3 3 2 5 8 8 8 6 TPR repeat TPR_16 PF13432.1 KUM55522.1 - 1.5e-15 57.3 2.9 0.00049 20.6 0.1 7.2 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.1 KUM55522.1 - 7.3e-15 53.5 16.7 0.018 14.8 0.1 9.8 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.1 KUM55522.1 - 8.4e-11 42.0 5.9 0.17 12.2 0.1 7.4 2 2 4 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 KUM55522.1 - 1.6e-10 40.2 2.3 4.7 7.6 0.0 7.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 KUM55522.1 - 1.6e-08 33.7 17.1 0.92 9.5 0.0 9.7 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_1 PF00515.23 KUM55522.1 - 5.5e-08 32.0 5.0 0.85 9.3 0.0 8.0 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_4 PF07721.9 KUM55522.1 - 2.7e-07 30.3 6.0 0.27 11.7 0.1 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat NB-ARC PF00931.17 KUM55522.1 - 3e-06 26.3 0.0 9.4e-06 24.6 0.0 1.9 1 1 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 KUM55522.1 - 1.3e-05 24.9 0.0 2.8e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_14 PF13428.1 KUM55522.1 - 1.5e-05 25.1 16.5 35 5.4 0.1 9.7 7 3 3 10 10 10 0 Tetratricopeptide repeat AAA_16 PF13191.1 KUM55522.1 - 0.0002 21.4 0.0 0.003 17.5 0.0 2.8 1 1 0 1 1 1 1 AAA ATPase domain TPR_8 PF13181.1 KUM55522.1 - 0.0055 16.4 8.8 11 6.0 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat AAA_22 PF13401.1 KUM55522.1 - 0.0066 16.5 0.0 0.024 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain TPR_20 PF14561.1 KUM55522.1 - 0.02 15.0 4.1 4.1 7.5 0.1 5.2 4 2 2 6 6 5 0 Tetratricopeptide repeat PPR PF01535.15 KUM55522.1 - 0.025 14.5 0.5 46 4.3 0.0 5.7 7 0 0 7 7 7 0 PPR repeat DUF429 PF04250.8 KUM55522.1 - 0.11 11.7 0.6 0.8 8.9 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF429) Arch_ATPase PF01637.13 KUM55522.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase ADH_zinc_N PF00107.21 KUM55524.1 - 4.4e-22 78.0 0.0 9.5e-22 76.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KUM55524.1 - 5.4e-07 30.5 0.0 1.4e-06 29.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Abhydrolase_6 PF12697.2 KUM55525.1 - 4.5e-06 26.7 0.0 4.5e-06 26.7 0.0 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM55525.1 - 0.00051 19.6 0.0 0.0013 18.3 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 KUM55525.1 - 0.0089 15.0 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 KUM55525.1 - 0.05 12.8 0.0 0.086 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Phage_terminase PF10668.4 KUM55526.1 - 0.084 12.6 0.1 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Phage terminase small subunit Connexin PF00029.14 KUM55526.1 - 0.093 12.7 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Connexin Mito_carr PF00153.22 KUM55527.1 - 3.1e-63 209.5 1.8 1.7e-22 78.9 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Nop14 PF04147.7 KUM55528.1 - 0.00031 18.8 9.8 0.00031 18.8 6.8 1.6 2 0 0 2 2 2 1 Nop14-like family CENP-B_dimeris PF09026.5 KUM55528.1 - 4 7.7 10.0 13 6.1 6.9 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CFEM PF05730.6 KUM55530.1 - 8.7e-11 41.4 10.8 1.6e-10 40.6 7.5 1.4 1 0 0 1 1 1 1 CFEM domain HSDR_N_2 PF13588.1 KUM55532.1 - 0.0052 16.5 0.0 0.008 15.9 0.0 1.4 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) MFS_1 PF07690.11 KUM55534.1 - 1.7e-33 115.7 21.3 2.7e-33 115.1 14.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Toxin_28 PF08115.6 KUM55534.1 - 0.12 12.0 0.5 0.27 10.9 0.3 1.6 1 0 0 1 1 1 0 SFI toxin family Sulfatase PF00884.18 KUM55535.1 - 4.2e-63 213.3 0.6 5.6e-63 212.9 0.4 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KUM55535.1 - 0.0046 16.3 3.6 0.055 12.7 2.5 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase bZIP_1 PF00170.16 KUM55536.1 - 0.012 15.5 0.2 0.024 14.5 0.1 1.4 1 0 0 1 1 1 0 bZIP transcription factor adh_short PF00106.20 KUM55537.1 - 1.7e-15 57.3 0.0 3.4e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM55537.1 - 2.9e-07 30.3 0.1 8.3e-07 28.8 0.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KUM55537.1 - 0.001 18.5 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KUM55537.1 - 0.024 13.5 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.21 KUM55538.1 - 7.6e-12 44.9 0.2 1.4e-11 44.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM55538.1 - 1.6e-09 37.4 0.0 1.4e-08 34.4 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Fungal_trans PF04082.13 KUM55541.1 - 2.8e-10 39.5 0.0 4.4e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM55541.1 - 5.6e-09 35.7 12.5 8.7e-09 35.1 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 KUM55541.1 - 8.9 6.5 11.3 13 6.0 7.3 1.8 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region DUF1330 PF07045.6 KUM55542.1 - 0.038 13.8 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1330) Phage_T7_Capsid PF05396.6 KUM55542.1 - 0.14 12.3 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Phage T7 capsid assembly protein p450 PF00067.17 KUM55545.1 - 1.7e-48 165.3 0.0 2.3e-48 164.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_11 PF00457.12 KUM55546.1 - 1.8e-69 232.7 11.1 2.2e-69 232.5 7.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 ADH_N PF08240.7 KUM55548.1 - 5.2e-19 68.0 0.4 5.2e-19 68.0 0.2 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM55548.1 - 1.7e-17 63.1 0.6 3.5e-17 62.1 0.4 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PQQ PF01011.16 KUM55548.1 - 0.023 14.1 0.1 0.063 12.8 0.1 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat zf-Tim10_DDP PF02953.10 KUM55549.1 - 1.4e-19 69.0 7.2 1.9e-19 68.7 5.0 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 KUM55549.1 - 0.043 13.2 5.8 0.069 12.6 4.0 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) GED PF02212.13 KUM55549.1 - 0.047 13.5 0.6 0.059 13.2 0.4 1.1 1 0 0 1 1 1 0 Dynamin GTPase effector domain Aminotran_1_2 PF00155.16 KUM55550.1 - 3.8e-06 26.1 0.0 4.4e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II zf-RING_2 PF13639.1 KUM55551.1 - 1.2e-15 57.0 5.4 2e-15 56.2 3.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KUM55551.1 - 4.6e-09 36.2 1.8 9.9e-09 35.1 1.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KUM55551.1 - 2.8e-08 33.2 4.2 5.4e-08 32.3 2.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KUM55551.1 - 6.3e-08 32.5 5.4 1.2e-07 31.5 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KUM55551.1 - 3.3e-06 26.6 1.8 3.3e-06 26.6 1.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KUM55551.1 - 9.2e-06 25.2 2.7 9.2e-06 25.2 1.9 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 KUM55551.1 - 0.00011 21.9 2.4 0.00026 20.7 1.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KUM55551.1 - 0.00034 20.1 3.5 0.00063 19.2 2.5 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 KUM55551.1 - 0.0096 15.9 2.4 0.021 14.8 1.7 1.6 1 0 0 1 1 1 1 RING-like domain zf-C3HC4_4 PF15227.1 KUM55551.1 - 0.18 11.6 9.9 0.032 14.0 4.0 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 KUM55551.1 - 4.2 7.4 9.3 2.1 8.3 3.8 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain GPI-anchored PF10342.4 KUM55558.1 - 2.9e-23 82.1 0.1 2.9e-23 82.1 0.1 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF1455 PF07306.6 KUM55558.1 - 0.043 13.8 3.2 0.071 13.1 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) Aldedh PF00171.17 KUM55559.1 - 4.4e-121 404.4 1.1 5.8e-121 404.0 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KUM55559.1 - 9e-05 21.3 0.1 0.00061 18.6 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) Aldo_ket_red PF00248.16 KUM55560.1 - 4.6e-39 133.9 0.0 5.3e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans_2 PF11951.3 KUM55565.1 - 1.8e-36 125.5 0.0 2.5e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM55565.1 - 2.1e-08 33.9 9.4 3.6e-08 33.1 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.1 KUM55566.1 - 1.8e-33 116.2 0.0 2.3e-33 115.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KUM55566.1 - 2.1e-28 99.3 0.1 2.5e-28 99.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM55566.1 - 5.9e-06 26.0 0.0 1.2e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 KR domain UPF0146 PF03686.8 KUM55566.1 - 0.037 13.8 0.1 0.088 12.6 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Epimerase PF01370.16 KUM55566.1 - 0.053 12.9 0.1 0.13 11.7 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KUM55566.1 - 0.094 12.5 0.7 0.17 11.6 0.5 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase CM_2 PF01817.16 KUM55567.1 - 2.8e-13 49.7 0.1 3.5e-13 49.4 0.1 1.1 1 0 0 1 1 1 1 Chorismate mutase type II Nucleic_acid_bd PF13820.1 KUM55567.1 - 0.0012 18.4 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 Putative nucleic acid-binding region HemX PF04375.9 KUM55567.1 - 0.054 12.0 0.1 0.066 11.8 0.1 1.1 1 0 0 1 1 1 0 HemX BAR PF03114.13 KUM55567.1 - 0.13 11.7 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 BAR domain Peptidase_M24 PF00557.19 KUM55568.1 - 4e-19 69.0 0.0 4.9e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24 PF00557.19 KUM55569.1 - 0.0013 18.4 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Fungal_trans PF04082.13 KUM55570.1 - 2.4e-22 79.0 0.5 2.7e-22 78.8 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain GATA PF00320.22 KUM55571.1 - 2.6e-15 55.4 5.2 4.3e-15 54.7 3.6 1.4 1 0 0 1 1 1 1 GATA zinc finger 5-nucleotidase PF06189.7 KUM55571.1 - 0.062 12.1 0.2 0.075 11.8 0.1 1.1 1 0 0 1 1 1 0 5'-nucleotidase zf-RING_3 PF14369.1 KUM55571.1 - 0.072 13.0 1.9 0.14 12.1 1.3 1.5 1 0 0 1 1 1 0 zinc-finger GSu_C4xC__C2xCH PF09698.5 KUM55571.1 - 0.23 11.6 3.3 0.45 10.7 2.3 1.5 1 0 0 1 1 1 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) zf-C2H2_jaz PF12171.3 KUM55574.1 - 4.1e-23 80.8 69.9 3.2e-05 23.9 2.4 10.1 11 0 0 11 11 11 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KUM55574.1 - 2.4e-20 72.0 65.1 0.00072 19.6 2.5 10.2 10 0 0 10 10 10 7 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KUM55574.1 - 2.7e-16 58.6 57.7 0.016 15.5 1.5 10.5 10 0 0 10 10 10 9 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KUM55574.1 - 4.2e-15 55.6 70.8 0.0074 16.3 1.7 9.7 1 1 8 9 9 9 8 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KUM55574.1 - 2.2e-11 43.3 72.3 0.18 12.1 0.6 10.7 10 1 0 10 10 10 9 Zinc finger, C2H2 type zf-C2HC_2 PF13913.1 KUM55574.1 - 4.2e-08 32.6 15.2 0.84 9.3 0.1 6.8 6 0 0 6 6 6 5 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 KUM55574.1 - 1.7e-05 24.8 43.4 0.11 12.7 0.5 9.9 10 0 0 10 10 10 3 Zinc-finger double domain zf-C2H2_6 PF13912.1 KUM55574.1 - 0.077 12.9 52.2 1.2 9.1 1.0 9.8 10 0 0 10 10 10 0 C2H2-type zinc finger Pkinase PF00069.20 KUM55576.1 - 1.7e-64 217.5 0.0 2.7e-64 216.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM55576.1 - 4.6e-27 94.7 0.0 7.8e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM55576.1 - 0.022 13.7 0.2 0.084 11.8 0.1 1.9 1 1 1 2 2 2 0 Kinase-like APH PF01636.18 KUM55576.1 - 0.13 12.0 0.7 1.2 8.8 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family FolB PF02152.13 KUM55578.1 - 3e-21 75.6 0.0 9.2e-18 64.4 0.0 2.2 2 0 0 2 2 2 2 Dihydroneopterin aldolase zf-C2H2_4 PF13894.1 KUM55579.1 - 2.5e-06 27.4 1.5 0.0064 16.7 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KUM55579.1 - 4.3e-06 26.7 0.8 0.069 13.5 0.3 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KUM55579.1 - 0.0024 17.7 0.7 1.4 8.9 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KUM55579.1 - 0.0061 16.7 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger double domain GAGA PF09237.6 KUM55579.1 - 0.082 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 GAGA factor LSM PF01423.17 KUM55582.1 - 7.8e-17 60.5 0.0 1e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KUM55582.1 - 8.1e-05 22.4 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF2763 PF10961.3 KUM55582.1 - 4.9 7.6 7.4 8.8 6.7 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) PetM PF08041.6 KUM55583.1 - 0.58 9.6 2.4 1 8.8 1.7 1.5 1 1 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 RNase_H PF00075.19 KUM55584.1 - 1.3e-05 25.4 0.0 2.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 RNase H TruD PF01142.13 KUM55585.1 - 1.3e-54 185.3 0.1 2.1e-50 171.4 0.0 4.0 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) SKG6 PF08693.5 KUM55586.1 - 1.7e-05 24.0 3.9 0.00011 21.4 0.2 3.2 3 0 0 3 3 3 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 KUM55586.1 - 2.8e-05 23.7 0.0 6.4e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) TMEM154 PF15102.1 KUM55586.1 - 0.0018 17.9 0.4 0.0018 17.9 0.3 2.0 2 0 0 2 2 2 1 TMEM154 protein family DUF3188 PF11384.3 KUM55586.1 - 0.021 14.3 0.3 0.066 12.7 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) Amino_oxidase PF01593.19 KUM55587.1 - 2e-35 122.7 0.0 2.7e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KUM55587.1 - 1.7e-05 24.7 0.1 7.3e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KUM55587.1 - 0.0016 17.5 0.0 0.0027 16.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HAD_2 PF13419.1 KUM55588.1 - 6.4e-24 85.1 0.0 7.8e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KUM55588.1 - 4.2e-05 23.1 0.0 6.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like DUF3226 PF11536.3 KUM55588.1 - 0.047 13.1 0.0 0.1 12.0 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3226) HTH_1 PF00126.22 KUM55588.1 - 0.054 13.2 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Zn_clus PF00172.13 KUM55590.1 - 7.1e-10 38.6 8.5 1.1e-09 37.9 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kelch_5 PF13854.1 KUM55591.1 - 1.3e-16 60.1 5.3 2.3e-14 52.9 0.4 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 KUM55591.1 - 1.5e-06 28.2 2.6 0.043 14.0 0.1 4.8 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.20 KUM55591.1 - 3.8e-06 26.3 0.1 0.026 14.0 0.0 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 KUM55591.1 - 0.0012 18.9 0.9 0.061 13.5 0.1 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 KUM55591.1 - 0.002 17.8 7.4 0.77 9.5 0.1 5.2 6 0 0 6 6 6 1 Galactose oxidase, central domain MASE1 PF05231.9 KUM55591.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 MASE1 Aminotran_3 PF00202.16 KUM55592.1 - 5e-38 130.7 0.0 9.1e-21 74.0 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 KUM55592.1 - 9.5e-37 126.5 0.0 2e-36 125.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 KUM55592.1 - 0.0037 16.6 0.2 0.02 14.3 0.0 2.2 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Aminotran_1_2 PF00155.16 KUM55594.1 - 2.6e-35 122.0 0.0 3.3e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.15 KUM55594.1 - 0.00012 20.8 0.0 0.00018 20.1 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.14 KUM55594.1 - 0.0015 17.3 0.0 0.19 10.4 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_3 PF00202.16 KUM55594.1 - 0.0016 17.3 0.0 0.0038 16.1 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-III Cys_Met_Meta_PP PF01053.15 KUM55594.1 - 0.13 10.5 0.0 0.16 10.1 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KUM55594.1 - 0.19 10.7 0.0 0.43 9.5 0.0 1.5 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family HNH_2 PF13391.1 KUM55595.1 - 4.1e-10 39.2 0.7 2.6e-09 36.7 0.2 2.5 2 0 0 2 2 2 1 HNH endonuclease MFS_1 PF07690.11 KUM55596.1 - 5.9e-31 107.4 48.8 5.9e-31 107.4 33.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM55596.1 - 3.7e-10 38.9 40.0 1.1e-08 34.1 9.2 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 KUM55596.1 - 0.00031 19.2 27.4 0.0006 18.3 17.7 2.1 1 1 0 1 1 1 1 MFS/sugar transport protein Glyco_transf_20 PF00982.16 KUM55597.1 - 1.5e-150 501.8 0.0 1.9e-150 501.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_trans_1_2 PF13524.1 KUM55597.1 - 0.0057 16.9 0.1 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 KUM55597.1 - 0.0065 15.8 0.2 0.21 10.9 0.1 2.9 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KUM55597.1 - 0.022 14.8 0.0 0.07 13.2 0.0 1.8 1 1 0 1 1 1 0 Glycosyl transferases group 1 DUF693 PF05113.8 KUM55597.1 - 0.038 12.9 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF693) AFG1_ATPase PF03969.11 KUM55597.1 - 0.15 10.8 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 AFG1-like ATPase FAD_binding_3 PF01494.14 KUM55599.1 - 6.8e-80 268.7 0.0 8.1e-80 268.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KUM55599.1 - 5e-06 26.4 0.0 1.6e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KUM55599.1 - 5.7e-05 22.1 0.3 0.00012 21.1 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KUM55599.1 - 9.9e-05 22.6 0.0 0.0017 18.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 KUM55599.1 - 0.00014 20.7 0.0 0.00037 19.4 0.0 1.6 1 1 0 1 1 1 1 Squalene epoxidase Pyr_redox_3 PF13738.1 KUM55599.1 - 0.00061 19.8 0.1 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KUM55599.1 - 0.0014 17.5 0.0 0.0028 16.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KUM55599.1 - 0.0014 17.1 0.0 0.0028 16.2 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 KUM55599.1 - 0.0017 17.4 0.0 0.0032 16.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KUM55599.1 - 0.003 17.4 0.0 0.0063 16.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KUM55599.1 - 0.0082 15.0 0.1 0.014 14.3 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 KUM55599.1 - 0.034 13.9 0.1 0.076 12.7 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding ApbA PF02558.11 KUM55599.1 - 0.09 12.2 0.2 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KUM55599.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Phosphoesterase PF04185.9 KUM55600.1 - 2.8e-61 207.8 0.3 5.2e-61 206.9 0.2 1.4 1 1 0 1 1 1 1 Phosphoesterase family Atrophin-1 PF03154.10 KUM55601.1 - 5.2 5.0 7.3 5.7 4.9 5.0 1.0 1 0 0 1 1 1 0 Atrophin-1 family WD40 PF00400.27 KUM55602.1 - 5e-188 603.1 21.5 5.6e-16 57.7 0.0 13.2 13 0 0 13 13 13 12 WD domain, G-beta repeat eIF2A PF08662.6 KUM55602.1 - 1.6e-16 60.6 0.0 0.00011 21.9 0.0 5.1 1 1 5 6 6 6 5 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KUM55602.1 - 2.7e-11 42.8 10.6 0.0045 15.7 0.1 6.4 1 1 6 7 7 7 3 Nup133 N terminal like Apc4_WD40 PF12894.2 KUM55602.1 - 9e-11 41.1 0.0 4.7 6.7 0.0 9.9 11 1 1 12 12 12 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.7 KUM55602.1 - 1.6e-10 40.3 0.9 21 4.9 0.0 10.0 12 0 0 12 12 12 0 WD40-like Beta Propeller Repeat IKI3 PF04762.7 KUM55602.1 - 3.8e-08 31.6 2.2 0.42 8.3 0.0 5.1 2 2 1 3 3 3 3 IKI3 family Nbas_N PF15492.1 KUM55602.1 - 1e-07 31.3 5.5 5.8 5.9 0.0 8.9 1 1 9 11 11 11 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 KUM55602.1 - 1.5e-07 30.0 0.1 2.8 6.1 0.0 4.8 1 1 4 5 5 5 3 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 KUM55602.1 - 5.3e-07 28.8 15.7 1.4 8.3 0.0 9.0 10 0 0 10 10 9 2 Proteasome subunit A N-terminal signature DUF642 PF04862.7 KUM55602.1 - 1e-05 25.2 0.0 7.5 6.1 0.0 5.3 1 1 3 6 6 6 0 Protein of unknown function (DUF642) Peptidase_S9_N PF02897.10 KUM55602.1 - 1.1e-05 24.1 1.0 2 6.9 0.0 5.0 4 2 1 5 5 5 2 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF1258 PF06869.7 KUM55602.1 - 1.7e-05 24.0 0.5 6 5.8 0.0 7.0 3 3 6 9 9 9 1 Protein of unknown function (DUF1258) MORN_2 PF07661.8 KUM55602.1 - 1.8e-05 24.2 0.0 19 5.6 0.0 7.4 10 0 0 10 10 7 0 MORN repeat variant Robl_LC7 PF03259.12 KUM55602.1 - 2.5e-05 23.7 1.4 23 4.6 0.0 7.1 9 0 0 9 9 8 0 Roadblock/LC7 domain WXG100 PF06013.7 KUM55602.1 - 0.00029 20.7 0.0 41 4.2 0.0 6.6 7 2 2 9 9 8 0 Proteins of 100 residues with WXG TruB_C PF09142.6 KUM55602.1 - 0.00031 20.3 0.0 75 3.0 0.0 6.3 8 0 0 8 8 6 0 tRNA Pseudouridine synthase II, C terminal Rax2 PF12768.2 KUM55602.1 - 0.0021 17.3 3.8 6.9 5.7 0.0 5.4 2 2 2 7 7 7 0 Cortical protein marker for cell polarity DUF4072 PF13284.1 KUM55602.1 - 0.0053 16.9 0.0 7.3 6.8 0.0 4.6 6 0 0 6 6 5 0 Domain of unknown function (DUF4072) DUF3312 PF11768.3 KUM55602.1 - 0.012 13.8 0.0 52 1.8 0.0 4.9 2 2 4 7 7 7 0 Protein of unknown function (DUF3312) DUF1652 PF07865.6 KUM55602.1 - 0.017 14.6 0.2 12 5.5 0.0 5.0 4 1 2 6 6 6 0 Protein of unknown function (DUF1652) CNH PF00780.17 KUM55602.1 - 0.034 13.5 0.0 7.7 5.8 0.0 4.6 6 3 3 9 9 9 0 CNH domain HARP PF07443.8 KUM55602.1 - 0.069 12.5 0.0 0.53 9.7 0.0 2.6 2 0 0 2 2 1 0 HepA-related protein (HARP) NACHT PF05729.7 KUM55603.1 - 0.0074 15.9 0.5 0.013 15.1 0.1 1.6 2 0 0 2 2 2 1 NACHT domain KAP_NTPase PF07693.9 KUM55603.1 - 0.14 11.1 0.5 0.21 10.5 0.4 1.2 1 0 0 1 1 1 0 KAP family P-loop domain NPV_P10 PF05531.7 KUM55604.1 - 0.0017 18.5 2.9 0.57 10.4 0.1 2.2 1 1 1 2 2 2 2 Nucleopolyhedrovirus P10 protein SF-assemblin PF06705.6 KUM55604.1 - 0.018 14.2 0.1 0.022 13.9 0.0 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin IDO PF01231.13 KUM55604.1 - 0.037 12.4 0.0 0.098 11.0 0.0 1.5 1 1 1 2 2 2 0 Indoleamine 2,3-dioxygenase DUF4208 PF13907.1 KUM55604.1 - 0.08 13.1 0.2 0.2 11.8 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4208) Cellulase PF00150.13 KUM55606.1 - 1.2e-18 67.3 6.5 1.9e-18 66.6 4.5 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KUM55606.1 - 3.4e-11 42.6 8.6 3.4e-11 42.6 6.0 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.12 KUM55606.1 - 0.00015 20.7 0.1 0.00038 19.4 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase-like PF12876.2 KUM55606.1 - 0.00063 20.1 0.0 0.0014 18.9 0.0 1.7 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_42 PF02449.10 KUM55606.1 - 0.0044 16.1 0.1 0.01 15.0 0.1 1.6 1 0 0 1 1 1 1 Beta-galactosidase Fungal_trans_2 PF11951.3 KUM55607.1 - 1.1e-07 30.7 0.8 1.4e-07 30.4 0.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain RCR PF12273.3 KUM55610.1 - 3.2e-25 89.1 12.9 4.8e-25 88.6 8.9 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF1183 PF06682.7 KUM55610.1 - 0.16 11.5 0.2 0.21 11.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Shisa PF13908.1 KUM55610.1 - 3.6 7.7 5.3 8.6 6.4 3.6 1.7 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Pro-rich PF15240.1 KUM55610.1 - 9 6.3 34.2 11 6.0 23.7 1.1 1 0 0 1 1 1 0 Proline-rich Sld5 PF05916.6 KUM55611.1 - 1.9e-10 40.9 0.2 2.8e-10 40.4 0.2 1.2 1 0 0 1 1 1 1 GINS complex protein MxiH PF09392.5 KUM55611.1 - 0.3 11.6 1.7 0.76 10.3 0.0 2.0 1 1 1 2 2 2 0 Type III secretion needle MxiH like RNase_H PF00075.19 KUM55612.1 - 8.5e-14 52.0 0.0 1.6e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 RNase H DDE_Tnp_IS1595 PF12762.2 KUM55612.1 - 0.11 12.2 0.1 0.34 10.7 0.0 1.8 1 1 0 1 1 1 0 ISXO2-like transposase domain MFS_1 PF07690.11 KUM55613.1 - 6.5e-33 113.8 24.7 9e-33 113.4 17.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 KUM55613.1 - 2.7 8.4 6.6 0.67 10.3 0.1 2.9 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Glyco_hydro_88 PF07470.8 KUM55614.1 - 7.3e-90 301.3 2.4 8.6e-90 301.1 1.7 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 KUM55614.1 - 0.0039 15.5 0.1 0.0051 15.1 0.0 1.1 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) adh_short_C2 PF13561.1 KUM55615.1 - 0.00032 20.5 0.0 0.00038 20.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DHDPS PF00701.17 KUM55616.1 - 1.6e-42 145.0 0.0 1.8e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family CbiD PF01888.12 KUM55616.1 - 0.038 12.9 0.1 0.47 9.3 0.0 2.1 2 0 0 2 2 2 0 CbiD HMGL-like PF00682.14 KUM55616.1 - 0.041 13.5 0.2 0.063 12.9 0.1 1.2 1 0 0 1 1 1 0 HMGL-like Peptidase_M57 PF12388.3 KUM55616.1 - 0.041 13.1 0.0 0.2 10.9 0.0 1.9 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Ank_2 PF12796.2 KUM55617.1 - 3.7e-28 97.6 0.1 2.2e-06 27.9 0.1 5.2 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KUM55617.1 - 4.6e-16 57.7 4.1 0.2 11.5 0.0 9.1 9 0 0 9 9 9 5 Ankyrin repeat Ank_3 PF13606.1 KUM55617.1 - 3.4e-11 42.2 0.6 0.26 11.6 0.0 9.0 9 0 0 9 9 9 1 Ankyrin repeat Ank_4 PF13637.1 KUM55617.1 - 4.2e-11 43.0 0.3 0.21 12.1 0.0 6.3 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM55617.1 - 3.7e-08 33.3 0.0 0.89 9.8 0.0 6.9 6 1 1 7 7 7 2 Ankyrin repeats (many copies) DUF1524 PF07510.6 KUM55618.1 - 3.2e-14 52.9 0.0 3.8e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.1 KUM55618.1 - 0.21 11.2 0.8 0.56 9.8 0.5 1.7 1 1 0 1 1 1 0 HNH endonuclease MFS_1 PF07690.11 KUM55619.1 - 8.5e-29 100.3 23.4 1.1e-28 100.0 16.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Oxidored_FMN PF00724.15 KUM55621.1 - 1.6e-65 221.3 0.0 9.3e-65 218.8 0.0 1.9 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FMN_dh PF01070.13 KUM55623.1 - 8.4e-87 291.3 0.2 1.6e-86 290.4 0.1 1.4 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KUM55623.1 - 6.5e-06 25.2 0.0 1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KUM55623.1 - 9.5e-06 24.7 1.6 0.00044 19.2 0.2 2.9 2 1 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KUM55623.1 - 0.039 13.1 0.1 0.067 12.3 0.1 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.16 KUM55623.1 - 0.048 12.9 0.0 0.13 11.4 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein DUF3716 PF12511.3 KUM55626.1 - 5e-09 35.6 3.5 7.8e-09 35.0 2.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF969 PF06149.7 KUM55626.1 - 0.058 12.6 0.0 0.083 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF969) Y_phosphatase2 PF03162.8 KUM55628.1 - 0.12 11.7 0.0 0.52 9.6 0.0 1.8 1 1 0 1 1 1 0 Tyrosine phosphatase family Ribonuc_L-PSP PF01042.16 KUM55629.1 - 1.4e-34 118.4 0.0 1.5e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Ole-e-6 PF09253.5 KUM55629.1 - 0.084 12.5 0.8 7.5 6.2 0.1 2.7 2 1 1 3 3 3 0 Pollen allergen ole e 6 ADH_zinc_N PF00107.21 KUM55630.1 - 2e-12 46.8 0.0 3.8e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM55630.1 - 1.8e-05 24.4 0.0 9e-05 22.2 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Ank_2 PF12796.2 KUM55631.1 - 1.7e-54 182.1 10.9 7.1e-17 61.5 0.1 6.0 2 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 KUM55631.1 - 3.3e-46 152.8 24.7 2e-06 27.3 0.1 12.0 12 0 0 12 12 12 9 Ankyrin repeat Ank_4 PF13637.1 KUM55631.1 - 9.1e-43 143.9 6.1 7.2e-07 29.5 0.0 7.5 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM55631.1 - 1.1e-37 127.2 14.1 3.8e-06 26.9 0.0 8.9 5 1 3 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM55631.1 - 4e-32 107.0 5.9 0.00083 19.3 0.0 11.0 11 0 0 11 11 11 8 Ankyrin repeat NACHT PF05729.7 KUM55631.1 - 5.5e-14 52.1 0.0 1e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.15 KUM55631.1 - 2.7e-13 49.4 0.0 7.5e-13 47.9 0.0 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_22 PF13401.1 KUM55631.1 - 4.6e-07 30.0 0.0 1.2e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KUM55631.1 - 0.00076 19.5 0.3 0.008 16.1 0.0 2.7 3 1 0 3 3 2 1 AAA ATPase domain AAA_14 PF13173.1 KUM55631.1 - 0.0059 16.4 0.0 0.045 13.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KUM55631.1 - 0.012 15.8 0.0 0.035 14.3 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KUM55631.1 - 0.013 14.3 0.1 0.032 13.0 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 KUM55631.1 - 0.02 15.0 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 KUM55631.1 - 0.027 14.1 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase KAP_NTPase PF07693.9 KUM55631.1 - 0.042 12.8 0.1 2.4 7.0 0.4 2.3 1 1 1 2 2 2 0 KAP family P-loop domain DUF1843 PF08898.5 KUM55631.1 - 0.15 12.0 4.9 15 5.7 0.1 4.7 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) MMR_HSR1 PF01926.18 KUM55632.1 - 9.3e-07 28.8 0.0 2.5e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KUM55632.1 - 3.1e-05 23.2 0.0 3.1e-05 23.2 0.0 1.9 2 0 0 2 2 1 1 AIG1 family Dynamin_N PF00350.18 KUM55632.1 - 4e-05 23.5 11.9 0.013 15.3 0.0 3.7 2 2 1 3 3 2 2 Dynamin family DUF258 PF03193.11 KUM55632.1 - 4.1e-05 22.8 0.0 0.00019 20.6 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 KUM55632.1 - 0.00028 21.1 2.4 0.0007 19.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KUM55632.1 - 0.0029 18.3 3.3 0.012 16.4 0.3 2.5 1 1 1 2 2 2 1 AAA domain ABC_tran PF00005.22 KUM55632.1 - 0.0063 16.8 4.2 0.017 15.4 0.0 2.6 2 1 0 2 2 2 1 ABC transporter Gtr1_RagA PF04670.7 KUM55632.1 - 0.0092 15.1 0.0 0.022 13.8 0.0 1.7 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_28 PF13521.1 KUM55632.1 - 0.014 15.3 3.1 0.6 10.0 0.0 3.1 3 1 0 3 3 3 0 AAA domain Miro PF08477.8 KUM55632.1 - 0.017 15.6 0.6 0.087 13.3 0.0 2.4 2 1 1 3 3 3 0 Miro-like protein FeoB_N PF02421.13 KUM55632.1 - 0.024 13.9 0.0 0.069 12.4 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B Allexi_40kDa PF05549.6 KUM55632.1 - 0.027 13.7 3.5 0.042 13.1 2.5 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein AAA_33 PF13671.1 KUM55632.1 - 0.035 13.9 0.2 0.32 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain IIGP PF05049.8 KUM55632.1 - 0.038 12.7 1.9 0.044 12.5 0.0 1.9 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Viral_helicase1 PF01443.13 KUM55632.1 - 0.05 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 KUM55632.1 - 0.06 13.4 1.0 0.16 12.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain Spore_IV_A PF09547.5 KUM55632.1 - 0.098 11.3 0.0 0.098 11.3 0.0 2.1 2 0 0 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) Exonuc_VII_L PF02601.10 KUM55632.1 - 0.1 11.7 6.9 0.16 11.1 4.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF87 PF01935.12 KUM55632.1 - 0.1 12.3 0.2 0.1 12.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_29 PF13555.1 KUM55632.1 - 0.14 11.6 0.0 0.54 9.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain FAM92 PF06730.6 KUM55632.1 - 0.15 11.4 8.7 0.62 9.3 6.0 1.9 1 1 0 1 1 1 0 FAM92 protein DUF4416 PF14385.1 KUM55632.1 - 0.25 11.0 1.9 0.48 10.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4416) YPEB PF14620.1 KUM55632.1 - 0.29 10.0 8.6 0.44 9.4 5.9 1.1 1 0 0 1 1 1 0 YpeB sporulation DivIVA PF05103.8 KUM55632.1 - 0.3 11.1 16.3 0.27 11.3 10.1 1.8 2 0 0 2 2 1 0 DivIVA protein SRP54 PF00448.17 KUM55632.1 - 0.37 10.2 3.2 0.45 9.9 0.1 2.5 2 1 1 3 3 3 0 SRP54-type protein, GTPase domain Tho2 PF11262.3 KUM55632.1 - 5.8 5.8 9.1 0.91 8.5 3.1 1.8 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Beta-lactamase PF00144.19 KUM55633.1 - 3.6e-40 137.9 0.0 5.4e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase TPMT PF05724.6 KUM55634.1 - 9e-28 97.2 0.0 1.3e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.2 KUM55634.1 - 1.4e-07 32.0 0.0 3.2e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM55634.1 - 1.6e-07 31.2 0.0 2.2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM55634.1 - 4.5e-07 29.5 0.0 2.9e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM55634.1 - 1.7e-06 28.3 0.0 3.6e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM55634.1 - 7.3e-06 26.3 0.0 2e-05 24.9 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain TehB PF03848.9 KUM55634.1 - 0.0015 17.7 0.0 0.0031 16.7 0.0 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_26 PF13659.1 KUM55634.1 - 0.004 17.1 0.0 0.0062 16.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain N2227 PF07942.7 KUM55634.1 - 0.025 13.5 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein AdoMet_MTase PF07757.8 KUM55634.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Thiolase_N PF00108.18 KUM55635.1 - 4.8e-68 228.9 0.7 4.8e-68 228.9 0.5 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KUM55635.1 - 1.9e-42 143.5 0.1 4.2e-42 142.4 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KUM55635.1 - 0.00025 20.6 0.8 0.0096 15.5 0.1 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.5 KUM55635.1 - 0.016 15.1 0.0 0.06 13.3 0.0 2.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.21 KUM55635.1 - 0.026 14.0 1.6 0.081 12.3 1.0 1.9 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.23 KUM55636.1 - 1.2e-63 214.9 0.0 1.6e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KUM55636.1 - 7.4e-05 23.6 0.0 0.00017 22.4 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Reticulon PF02453.12 KUM55637.1 - 0.3 10.7 3.2 0.3 10.6 2.2 1.0 1 0 0 1 1 1 0 Reticulon RhoGAP PF00620.22 KUM55638.1 - 5e-37 126.8 0.0 8e-37 126.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain MFS_1 PF07690.11 KUM55639.1 - 0.0024 16.6 13.2 0.0056 15.4 8.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_Mycoplasma PF07672.8 KUM55639.1 - 0.0028 16.8 0.0 0.0069 15.5 0.0 1.7 1 0 0 1 1 1 1 Mycoplasma MFS transporter CoA_binding_3 PF13727.1 KUM55639.1 - 0.16 11.7 4.5 0.54 10.0 0.1 2.3 1 1 1 2 2 2 0 CoA-binding domain DUF3112 PF11309.3 KUM55639.1 - 1.5 8.5 9.2 3.4 7.4 6.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) MFS_1 PF07690.11 KUM55641.1 - 3.7e-18 65.3 21.5 4.3e-18 65.1 14.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 KUM55642.1 - 4.2e-26 91.5 16.5 5.4e-26 91.1 11.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM55642.1 - 5.2e-11 41.7 6.5 7.6e-11 41.2 4.5 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KUM55642.1 - 0.0059 14.8 2.2 0.0077 14.4 1.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2206 PF09971.4 KUM55642.1 - 0.056 12.2 0.3 0.11 11.3 0.2 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) HATPase_c PF02518.21 KUM55643.1 - 9.9e-21 73.5 0.0 1.8e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KUM55643.1 - 1.1e-19 70.4 0.1 2.1e-19 69.5 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KUM55643.1 - 5e-13 48.8 0.0 1.3e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Inhibitor_G39P PF11417.3 KUM55644.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Loader and inhibitor of phage G40P FTR1 PF03239.9 KUM55645.1 - 1.7e-89 299.8 5.0 2e-89 299.5 3.4 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF3169 PF11368.3 KUM55645.1 - 0.025 13.8 1.4 0.094 11.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Wzy_C PF04932.10 KUM55645.1 - 0.031 14.0 6.3 0.041 13.6 0.2 2.6 2 2 0 2 2 2 0 O-Antigen ligase DUF4064 PF13273.1 KUM55645.1 - 0.2 11.7 5.2 0.27 11.3 1.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) PrgI PF12666.2 KUM55645.1 - 0.23 11.6 0.1 0.23 11.6 0.1 3.4 4 0 0 4 4 4 0 PrgI family protein DUF2207 PF09972.4 KUM55645.1 - 0.23 9.9 0.7 1.4 7.4 0.0 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF1043 PF06295.7 KUM55645.1 - 0.29 10.7 2.0 3.6 7.2 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Cu-oxidase_2 PF07731.9 KUM55646.1 - 3.8e-45 152.7 8.5 6.2e-41 139.1 0.5 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KUM55646.1 - 1.9e-41 140.4 8.2 5.1e-39 132.6 1.4 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KUM55646.1 - 1.4e-34 119.2 3.4 9.9e-32 110.0 0.4 3.2 3 0 0 3 3 3 2 Multicopper oxidase PPC PF04151.10 KUM55646.1 - 0.3 12.0 3.1 1.1 10.2 0.0 3.2 3 1 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain TPR_11 PF13414.1 KUM55649.1 - 3e-48 161.3 25.4 4e-18 64.8 1.3 6.0 4 2 2 6 6 5 5 TPR repeat TPR_1 PF00515.23 KUM55649.1 - 1.9e-37 125.3 12.3 1.5e-08 33.8 0.5 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 KUM55649.1 - 2.9e-36 120.4 9.2 2.5e-06 26.9 0.3 7.9 7 0 0 7 7 7 6 Tetratricopeptide repeat DnaJ PF00226.26 KUM55649.1 - 8.6e-27 92.6 2.2 8.6e-27 92.6 1.5 2.4 3 0 0 3 3 1 1 DnaJ domain TPR_16 PF13432.1 KUM55649.1 - 1.2e-26 92.7 8.0 7.4e-07 29.6 0.2 6.1 4 2 1 5 5 5 5 Tetratricopeptide repeat TPR_19 PF14559.1 KUM55649.1 - 8.9e-23 80.4 17.5 2.5e-06 27.7 0.0 6.2 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 KUM55649.1 - 6.8e-20 69.7 9.8 0.03 14.9 0.1 8.2 3 3 5 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.1 KUM55649.1 - 2.8e-18 65.6 9.4 9.4e-06 25.4 0.5 6.2 4 2 2 6 6 6 4 Tetratricopeptide repeat Apc3 PF12895.2 KUM55649.1 - 4.3e-18 65.2 5.2 8.7e-08 32.2 0.0 4.3 2 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 KUM55649.1 - 8.9e-18 62.9 11.7 0.00095 19.1 0.6 7.0 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 KUM55649.1 - 1.8e-14 52.3 15.4 0.00062 19.3 0.2 8.0 8 1 0 8 8 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 KUM55649.1 - 1.9e-13 49.0 4.9 0.68 9.8 0.0 7.5 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.1 KUM55649.1 - 3.4e-12 46.0 2.9 0.00039 20.2 0.0 5.0 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 KUM55649.1 - 1.3e-09 37.8 13.3 0.19 12.2 0.0 7.8 6 2 1 8 8 6 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KUM55649.1 - 6.6e-09 35.5 10.1 0.0057 16.4 0.2 5.7 4 2 2 6 6 6 3 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.1 KUM55649.1 - 1.3e-07 31.0 10.8 0.021 13.9 0.1 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat Rapsyn_N PF10579.4 KUM55649.1 - 0.0015 18.3 0.2 0.3 10.9 0.0 4.2 3 2 2 5 5 5 1 Rapsyn N-terminal myristoylation and linker region DUF928 PF06051.7 KUM55649.1 - 0.0027 17.3 1.0 0.46 10.0 0.0 2.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF928) Alkyl_sulf_dimr PF14863.1 KUM55649.1 - 0.0039 17.4 5.4 9.2 6.4 0.1 4.6 2 2 3 5 5 5 0 Alkyl sulfatase dimerisation TPR_20 PF14561.1 KUM55649.1 - 0.0072 16.4 10.4 1.7 8.8 0.0 5.4 3 2 1 5 5 4 1 Tetratricopeptide repeat BTAD PF03704.12 KUM55649.1 - 0.0081 16.4 1.2 1.2 9.4 0.3 3.6 3 1 0 3 3 3 1 Bacterial transcriptional activator domain DUF3856 PF12968.2 KUM55649.1 - 0.0084 15.9 6.0 16 5.3 0.4 5.7 4 2 0 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_4 PF07721.9 KUM55649.1 - 0.011 16.0 2.5 1.8 9.2 0.0 4.5 5 0 0 5 5 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 KUM55649.1 - 0.026 13.7 1.0 10 5.4 0.0 4.4 5 0 0 5 5 4 0 SHNi-TPR MIT PF04212.13 KUM55649.1 - 0.076 12.9 7.4 8.4 6.3 0.1 4.6 3 1 1 4 4 3 0 MIT (microtubule interacting and transport) domain RPT PF13446.1 KUM55649.1 - 0.086 12.2 0.5 4.9 6.6 0.0 3.7 3 0 0 3 3 3 0 A repeated domain in UCH-protein PPR PF01535.15 KUM55649.1 - 0.18 11.8 0.5 31 4.8 0.0 3.8 5 0 0 5 5 2 0 PPR repeat ChAPs PF09295.5 KUM55649.1 - 0.23 10.1 2.3 14 4.3 0.0 2.6 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) HEAT_2 PF13646.1 KUM55649.1 - 0.29 11.4 2.9 0.54 10.5 0.3 2.5 2 0 0 2 2 2 0 HEAT repeats GRP PF07172.6 KUM55649.1 - 0.59 10.6 10.8 1.4 9.3 7.5 1.7 1 0 0 1 1 1 0 Glycine rich protein family MFS_1 PF07690.11 KUM55650.1 - 1.5e-21 76.5 12.4 1.5e-21 76.5 8.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Toxin_18 PF08087.6 KUM55650.1 - 0.23 11.2 3.8 0.97 9.2 0.6 2.7 2 0 0 2 2 2 0 Conotoxin O-superfamily Amidohydro_3 PF07969.6 KUM55651.1 - 3.2e-56 191.2 0.4 3.7e-56 191.0 0.3 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KUM55651.1 - 2.7e-11 43.1 0.1 1.1e-10 41.1 0.0 2.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KUM55651.1 - 3.2e-05 24.0 2.3 0.032 14.2 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 KUM55651.1 - 0.00026 20.7 2.9 0.11 12.1 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family MFS_1 PF07690.11 KUM55652.1 - 1.8e-22 79.5 28.3 1.8e-22 79.5 19.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 KUM55653.1 - 7.7e-16 58.0 0.0 7.2e-15 54.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM55653.1 - 3.9e-06 26.1 0.0 6.5e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Zn_clus PF00172.13 KUM55654.1 - 1.9e-08 34.0 10.4 1.9e-08 34.0 7.2 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AflR PF08493.5 KUM55654.1 - 0.00011 21.3 9.7 0.00047 19.2 6.7 1.9 1 1 1 2 2 2 1 Aflatoxin regulatory protein Fungal_trans PF04082.13 KUM55655.1 - 1.9e-11 43.3 0.1 2e-10 39.9 0.1 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain HBS1_N PF08938.5 KUM55655.1 - 0.056 13.5 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 HBS1 N-terminus ADH_N PF08240.7 KUM55656.1 - 1.5e-21 76.2 6.5 2.4e-21 75.5 4.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM55656.1 - 6.4e-18 64.5 0.0 1e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KUM55656.1 - 0.00083 18.5 0.1 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KUM55656.1 - 0.088 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Fungal_trans PF04082.13 KUM55657.1 - 1.3e-14 53.7 2.5 1.3e-14 53.7 1.7 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM55657.1 - 1.2e-08 34.7 9.2 2.2e-08 33.8 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 KUM55658.1 - 2.8e-14 52.8 0.0 1e-13 51.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM55658.1 - 2.9e-13 49.5 0.0 1.4e-12 47.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KUM55658.1 - 0.011 14.7 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KUM55658.1 - 0.026 14.2 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family TEP1_N PF05386.6 KUM55658.1 - 0.16 11.4 0.6 0.3 10.5 0.4 1.5 1 0 0 1 1 1 0 TEP1 N-terminal domain DLH PF01738.13 KUM55659.1 - 4.8e-15 55.4 0.0 5.9e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KUM55659.1 - 0.00044 20.0 0.0 0.00061 19.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM55659.1 - 0.028 13.9 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold SNF2_N PF00176.18 KUM55661.1 - 3e-67 226.5 0.1 6e-67 225.5 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KUM55661.1 - 9.7e-18 63.8 0.1 5.2e-17 61.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KUM55661.1 - 2.6e-05 24.1 0.0 0.00015 21.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Acetyltransf_3 PF13302.1 KUM55662.1 - 1.3e-10 41.6 0.0 1.6e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KUM55662.1 - 0.023 14.6 0.1 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family NMT1 PF09084.6 KUM55665.1 - 5.3e-77 258.2 0.0 7e-77 257.8 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 KUM55665.1 - 2.2e-08 33.8 3.4 0.025 13.9 0.4 3.2 2 1 0 3 3 3 3 NMT1-like family Glycogen_syn PF05693.8 KUM55667.1 - 0 1124.3 0.0 0 1124.0 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 KUM55667.1 - 1.3e-05 24.7 0.0 0.00097 18.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KUM55667.1 - 1.8e-05 24.9 0.2 4.3e-05 23.7 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.6 KUM55667.1 - 2.9e-05 23.6 0.0 7e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Starch synthase catalytic domain F1F0-ATPsyn_F PF10791.4 KUM55668.1 - 3.3e-41 139.4 0.2 3.7e-41 139.2 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 KUM55668.1 - 5.3e-05 23.2 0.0 6.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f ETC_C1_NDUFA4 PF04800.7 KUM55669.1 - 3.6e-36 123.0 2.1 5.1e-36 122.5 1.5 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region DDE_3 PF13358.1 KUM55671.1 - 0.00016 21.4 0.0 0.00022 21.0 0.0 1.2 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF2036 PF09724.4 KUM55671.1 - 0.13 11.4 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2036) Sugar_tr PF00083.19 KUM55672.1 - 8.4e-06 24.6 0.4 9.6e-06 24.4 0.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Lipase_3 PF01764.20 KUM55673.1 - 2.6e-23 82.2 0.0 4.1e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Ank_2 PF12796.2 KUM55675.1 - 1.3e-72 240.1 23.2 1.6e-21 76.3 1.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KUM55675.1 - 4.8e-50 164.9 27.5 2.9e-06 26.7 0.2 8.7 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.1 KUM55675.1 - 1.3e-35 121.0 12.4 5.3e-07 29.9 0.2 7.7 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM55675.1 - 4.9e-30 102.8 19.7 3.8e-07 30.1 0.6 7.2 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM55675.1 - 2.8e-22 76.5 15.0 0.083 13.1 0.0 9.1 9 0 0 9 9 9 6 Ankyrin repeat PNP_UDP_1 PF01048.15 KUM55675.1 - 1.9e-14 53.2 0.2 2.4e-13 49.6 0.2 2.3 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 KUM55675.1 - 2.3e-11 43.6 0.1 4.4e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KUM55675.1 - 7e-07 29.4 1.1 1.3e-05 25.2 0.1 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KUM55675.1 - 0.00015 21.9 0.0 0.00081 19.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2521 PF10730.4 KUM55675.1 - 0.011 15.6 0.5 62 3.3 0.0 4.5 2 2 2 4 4 4 0 Protein of unknown function (DUF2521) NB-ARC PF00931.17 KUM55675.1 - 0.036 12.9 0.0 0.081 11.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain SNAP PF14938.1 KUM55675.1 - 0.41 9.7 4.6 1.2 8.2 0.4 2.8 1 1 2 3 3 3 0 Soluble NSF attachment protein, SNAP Ribonuc_L-PSP PF01042.16 KUM55676.1 - 8.5e-22 77.1 0.0 1.1e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Fungal_trans PF04082.13 KUM55677.1 - 6.7e-14 51.3 0.1 4.2e-13 48.7 0.0 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM55677.1 - 6.2e-08 32.4 5.5 1.3e-07 31.4 3.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N PF02798.15 KUM55678.1 - 4.7e-12 45.9 0.0 3.1e-11 43.2 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KUM55678.1 - 4.8e-12 45.6 0.0 7.9e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KUM55678.1 - 5.8e-10 39.2 0.0 9.9e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KUM55678.1 - 5.4e-09 35.9 0.0 2.7e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KUM55678.1 - 5.7e-07 29.9 0.0 8.4e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KUM55678.1 - 0.0005 19.8 0.0 0.0011 18.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.11 KUM55679.1 - 2.3e-24 85.7 47.3 2.3e-24 85.7 32.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1129 PF06570.6 KUM55679.1 - 0.0086 15.4 0.2 0.0086 15.4 0.1 3.2 2 2 1 3 3 3 1 Protein of unknown function (DUF1129) Ribosomal_L28e PF01778.12 KUM55680.1 - 2.2e-33 115.1 4.5 5.3e-33 113.8 3.1 1.6 1 1 0 1 1 1 1 Ribosomal L28e protein family Ldh_1_N PF00056.18 KUM55681.1 - 0.2 11.4 0.8 0.2 11.4 0.6 1.0 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain RRM_1 PF00076.17 KUM55682.1 - 4.4e-33 112.7 0.0 2.3e-15 55.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM55682.1 - 6.1e-21 74.1 0.1 1.9e-09 37.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM55682.1 - 4.3e-15 55.2 0.0 1.5e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 KUM55682.1 - 0.0071 15.8 0.1 0.19 11.2 0.0 2.4 2 0 0 2 2 2 1 Ribonuclease B OB domain Limkain-b1 PF11608.3 KUM55682.1 - 0.0083 15.8 0.2 0.16 11.7 0.0 2.1 2 0 0 2 2 2 1 Limkain b1 Cas_Cas2CT1978 PF09707.5 KUM55682.1 - 0.067 13.1 0.0 8.3 6.4 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) DUF605 PF04652.11 KUM55682.1 - 0.076 12.3 13.5 0.092 12.1 9.3 1.1 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 KUM55682.1 - 0.23 9.6 16.5 0.28 9.3 11.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2015 PF09435.5 KUM55683.1 - 5.8e-48 161.8 0.0 6.5e-48 161.7 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Mito_carr PF00153.22 KUM55684.1 - 4.5e-60 199.3 1.9 1.3e-21 76.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tom7 PF08038.7 KUM55685.1 - 6.4e-19 67.1 0.3 8.7e-19 66.7 0.2 1.2 1 0 0 1 1 1 1 TOM7 family E1-E2_ATPase PF00122.15 KUM55687.1 - 2.6e-63 213.1 5.3 2.6e-63 213.1 3.7 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KUM55687.1 - 9.7e-46 155.5 6.4 9.7e-46 155.5 4.4 2.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KUM55687.1 - 1.7e-30 107.0 0.0 8e-30 104.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KUM55687.1 - 1.1e-19 70.2 0.0 2e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KUM55687.1 - 1.6e-19 69.1 0.0 4.9e-19 67.5 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KUM55687.1 - 5.7e-17 62.5 0.1 2.6e-16 60.3 0.0 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KUM55687.1 - 8.3e-07 28.8 3.2 2.1e-05 24.2 1.7 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KUM55687.1 - 0.055 13.6 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF2222 PF09984.4 KUM55687.1 - 0.084 12.3 0.1 5.7 6.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized signal transduction histidine kinase domain (DUF2222) adh_short PF00106.20 KUM55688.1 - 4.2e-28 98.3 1.4 5.6e-28 97.9 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM55688.1 - 2.6e-22 79.7 0.2 3.7e-22 79.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM55688.1 - 9.1e-12 44.9 0.3 1.4e-11 44.3 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM55688.1 - 0.023 14.1 0.1 0.078 12.4 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3391 PF11871.3 KUM55688.1 - 0.073 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) MFS_1 PF07690.11 KUM55689.1 - 3.8e-32 111.3 30.2 3.8e-32 111.3 20.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily GFO_IDH_MocA_C PF02894.12 KUM55690.1 - 9.7e-18 64.0 0.2 2.3e-17 62.8 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.17 KUM55690.1 - 2.2e-17 63.6 0.0 4e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Fungal_trans PF04082.13 KUM55691.1 - 3e-16 59.0 2.1 5.4e-16 58.2 1.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2415 PF10313.4 KUM55693.1 - 6.7e-16 57.6 0.0 3.6e-15 55.3 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 KUM55693.1 - 0.029 14.2 3.4 1.5 8.8 0.3 3.6 4 0 0 4 4 4 0 WD domain, G-beta repeat MFS_1 PF07690.11 KUM55694.1 - 3.1e-21 75.4 25.5 4.2e-21 75.0 15.2 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily Peptidase_M50 PF02163.17 KUM55694.1 - 0.12 11.2 2.2 0.27 10.1 1.5 1.6 1 0 0 1 1 1 0 Peptidase family M50 Beta-lactamase PF00144.19 KUM55695.1 - 8.6e-10 38.1 0.1 1.1e-09 37.8 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 KUM55696.1 - 6.6e-09 35.5 0.0 9.4e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) COesterase PF00135.23 KUM55698.1 - 1.4e-80 271.5 0.0 1.6e-80 271.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KUM55698.1 - 4.2e-08 33.0 0.2 1.7e-07 31.0 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KUM55698.1 - 0.15 10.7 0.0 0.94 8.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Syntaxin-18_N PF10496.4 KUM55700.1 - 2.3e-17 62.5 0.4 2.3e-17 62.5 0.3 2.2 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 KUM55700.1 - 3.9e-05 23.2 1.6 0.00016 21.3 1.1 2.1 2 0 0 2 2 2 1 SNARE domain AATF-Che1 PF13339.1 KUM55700.1 - 0.28 11.3 4.7 3.4 7.8 0.1 2.7 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF3819 PF12842.2 KUM55700.1 - 0.47 10.1 3.5 0.25 11.0 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3819) CorA PF01544.13 KUM55700.1 - 9.8 5.1 8.0 1.7 7.5 0.2 2.9 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein PhzC-PhzF PF02567.11 KUM55701.1 - 2.2e-12 46.7 0.0 2.8e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein TPR_11 PF13414.1 KUM55702.1 - 1.8e-13 49.9 2.5 7.6e-09 35.0 0.1 3.2 1 1 2 3 3 3 2 TPR repeat TPR_1 PF00515.23 KUM55702.1 - 1.1e-12 46.9 6.3 3.3e-06 26.4 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KUM55702.1 - 6.3e-12 44.4 4.8 0.00054 19.6 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 KUM55702.1 - 1.8e-08 33.5 0.2 0.00031 20.3 0.0 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 KUM55702.1 - 7.9e-08 32.1 0.2 0.0002 21.2 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat PB1 PF00564.19 KUM55702.1 - 3.7e-06 26.5 0.1 6.5e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 PB1 domain TPR_7 PF13176.1 KUM55702.1 - 9.2e-06 25.0 0.7 7.6e-05 22.2 0.1 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KUM55702.1 - 1.8e-05 25.2 0.3 0.012 16.2 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KUM55702.1 - 5.2e-05 23.0 0.1 0.23 11.3 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 KUM55702.1 - 0.00031 20.9 0.3 11 6.6 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 KUM55702.1 - 0.016 15.3 0.0 0.65 10.3 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat LisH PF08513.6 KUM55703.1 - 1.4e-05 24.6 1.6 4.4e-05 23.0 0.2 2.2 2 0 0 2 2 2 1 LisH DUF3533 PF12051.3 KUM55703.1 - 1.8 7.2 4.6 0.92 8.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3533) DUF2096 PF09869.4 KUM55704.1 - 0.068 13.0 0.1 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) Ferric_reduct PF01794.14 KUM55705.1 - 3.4e-21 75.6 9.7 3.4e-21 75.6 6.7 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KUM55705.1 - 6.6e-17 61.8 0.0 9.4e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KUM55705.1 - 2.9e-08 33.5 0.0 6.3e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 KUM55705.1 - 9.6e-06 26.1 0.0 3.3e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF3975 PF13126.1 KUM55705.1 - 1.8 8.7 8.5 0.28 11.3 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3975) CRAL_TRIO PF00650.15 KUM55706.1 - 1.6e-44 151.1 0.0 2.6e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KUM55706.1 - 4.3e-13 49.4 0.0 6.9e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KUM55706.1 - 3.9e-09 36.4 0.0 1.2e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Ctr PF04145.10 KUM55707.1 - 1.8e-35 122.0 5.0 2.2e-35 121.8 3.5 1.1 1 0 0 1 1 1 1 Ctr copper transporter family SelR PF01641.13 KUM55709.1 - 6.4e-44 148.6 0.9 7.9e-44 148.3 0.6 1.1 1 0 0 1 1 1 1 SelR domain DZR PF12773.2 KUM55709.1 - 0.1 12.3 3.2 8 6.3 0.1 2.5 2 1 0 2 2 2 0 Double zinc ribbon DNA_RNApol_7kD PF03604.8 KUM55709.1 - 0.8 9.2 3.7 16 5.1 0.3 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit DUF3268 PF11672.3 KUM55709.1 - 9.8 6.3 7.4 45 4.1 2.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3268) ArfGap PF01412.13 KUM55710.1 - 2e-40 137.2 0.5 3e-40 136.6 0.3 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Aa_trans PF01490.13 KUM55711.1 - 4.7e-25 87.9 33.5 6e-25 87.5 23.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein UPF0182 PF03699.8 KUM55711.1 - 1.1 7.1 7.5 0.041 11.8 1.1 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0182) YMF19 PF02326.10 KUM55712.1 - 0.085 13.4 4.2 0.1 13.1 2.9 1.2 1 0 0 1 1 1 0 Plant ATP synthase F0 GCV_T PF01571.16 KUM55714.1 - 5e-58 195.9 0.0 6.7e-58 195.5 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KUM55714.1 - 2.2e-20 72.4 0.2 5.8e-20 71.1 0.1 1.7 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain LVIVD PF08309.6 KUM55714.1 - 0.00086 18.2 0.0 0.0018 17.2 0.0 1.5 1 0 0 1 1 1 1 LVIVD repeat Glyco_hydro_92 PF07971.7 KUM55715.1 - 6.5e-58 196.6 0.0 7.3e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 adh_short PF00106.20 KUM55718.1 - 5.1e-23 81.8 0.1 7.3e-23 81.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM55718.1 - 4.9e-21 75.5 0.1 6.7e-21 75.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM55718.1 - 9.2e-09 35.2 0.1 1.6e-08 34.3 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM55718.1 - 0.00082 18.8 0.0 0.0015 17.9 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family CLU PF13236.1 KUM55718.1 - 0.055 12.8 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Clustered mitochondria AATase PF07247.7 KUM55720.1 - 1.7e-16 59.8 0.0 3e-16 59.0 0.0 1.4 1 1 0 1 1 1 1 Alcohol acetyltransferase Oxidored_FMN PF00724.15 KUM55721.1 - 6.9e-97 324.4 0.0 7.8e-97 324.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family RFX_DNA_binding PF02257.10 KUM55722.1 - 1.4e-29 102.0 0.2 3.7e-29 100.6 0.1 1.8 1 0 0 1 1 1 1 RFX DNA-binding domain HTH_32 PF13565.1 KUM55722.1 - 0.036 14.8 0.1 0.26 12.0 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain Sulfatase PF00884.18 KUM55723.1 - 1.1e-21 77.3 0.5 2.4e-21 76.2 0.4 1.6 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KUM55723.1 - 7.1e-05 22.2 0.4 0.00017 21.0 0.1 1.7 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Fungal_trans PF04082.13 KUM55725.1 - 2.6e-09 36.3 0.4 2.9e-09 36.1 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_71 PF03659.9 KUM55726.1 - 2e-28 98.9 8.5 3.4e-18 65.2 0.4 3.2 1 1 1 3 3 3 3 Glycosyl hydrolase family 71 Trypsin PF00089.21 KUM55727.1 - 0.036 13.6 0.0 0.22 11.0 0.0 2.1 2 0 0 2 2 2 0 Trypsin Peptidase_S7 PF00949.16 KUM55727.1 - 0.13 11.6 0.0 0.29 10.5 0.0 1.6 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Ku_PK_bind PF08785.6 KUM55729.1 - 1.5e-17 63.5 0.0 2.7e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.11 KUM55729.1 - 3.2e-14 52.8 0.0 6.1e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KUM55730.1 - 1.7e-16 60.3 0.1 2.2e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.11 KUM55730.1 - 5.3e-07 29.2 0.1 1.1e-06 28.1 0.0 1.6 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain VWA_2 PF13519.1 KUM55730.1 - 1.1e-05 25.6 0.1 1.7e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KUM55730.1 - 0.00083 19.1 0.8 0.0079 15.9 0.3 2.2 1 1 1 2 2 2 1 von Willebrand factor type A domain Sugar_tr PF00083.19 KUM55731.1 - 2.1e-86 290.3 20.4 2.5e-86 290.0 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM55731.1 - 7.1e-13 47.9 35.9 2.4e-12 46.2 17.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1700 PF08006.6 KUM55731.1 - 1.3 8.3 5.9 3.2 6.9 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) DUF4149 PF13664.1 KUM55732.1 - 4.8e-25 87.5 4.5 7.6e-25 86.9 2.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) RRM_1 PF00076.17 KUM55734.1 - 3.1e-46 154.8 0.0 7.8e-17 60.6 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM55734.1 - 3.7e-28 97.3 0.0 1.9e-09 37.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM55734.1 - 2.3e-22 78.5 0.0 2.5e-08 33.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KUM55734.1 - 9.4e-06 25.4 0.0 9.6e-05 22.1 0.0 2.3 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 KUM55734.1 - 0.00011 21.9 0.0 0.0084 15.8 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Cytochrom_B_C PF00032.12 KUM55736.1 - 0.18 12.0 4.9 0.21 11.8 3.4 1.2 1 0 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD Dimer_Tnp_hAT PF05699.9 KUM55737.1 - 2.1e-11 43.2 0.0 5.5e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 KUM55737.1 - 0.1 12.5 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Ank_2 PF12796.2 KUM55739.1 - 2.6e-68 226.3 1.1 3.2e-16 59.4 0.0 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KUM55739.1 - 9.9e-47 156.5 7.5 1.9e-08 34.5 0.0 6.6 2 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.25 KUM55739.1 - 3.2e-46 152.8 1.5 4.3e-07 29.4 0.1 8.4 8 0 0 8 8 8 8 Ankyrin repeat Ank_3 PF13606.1 KUM55739.1 - 2.2e-36 120.2 0.2 0.0002 21.2 0.0 8.5 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 KUM55739.1 - 8.7e-36 121.1 4.3 5.9e-09 35.8 0.0 7.4 2 2 6 8 8 8 8 Ankyrin repeats (many copies) F-box PF00646.28 KUM55739.1 - 0.077 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 F-box domain MMgT PF10270.4 KUM55741.1 - 8.5e-34 116.1 0.0 9.7e-34 115.9 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter N_methyl_3 PF13633.1 KUM55741.1 - 3.7 7.6 9.3 0.1 12.5 2.4 1.6 2 0 0 2 2 2 0 Prokaryotic N-terminal methylation site Ank_5 PF13857.1 KUM55742.1 - 1.4e-05 25.1 0.0 0.079 13.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KUM55742.1 - 1.7e-05 25.1 0.0 0.00091 19.6 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KUM55742.1 - 6.1e-05 23.2 0.0 0.00028 21.1 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KUM55742.1 - 0.0064 16.6 0.0 3 8.3 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.25 KUM55742.1 - 0.0088 15.8 0.0 6.6 6.7 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeat Herpes_gE PF02480.11 KUM55743.1 - 0.0015 16.9 0.0 0.0016 16.7 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 KUM55743.1 - 0.0059 16.9 0.1 0.024 15.0 0.1 2.1 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Trp_oprn_chp PF09534.5 KUM55743.1 - 0.0073 15.9 0.1 0.0094 15.5 0.0 1.2 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CbtA PF09490.5 KUM55743.1 - 0.014 14.6 0.1 0.021 14.1 0.1 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Gly-zipper_Omp PF13488.1 KUM55743.1 - 0.024 14.2 5.2 0.064 12.9 3.6 1.6 1 1 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.1 KUM55743.1 - 0.024 14.1 3.7 0.045 13.2 2.5 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper TMEM51 PF15345.1 KUM55743.1 - 0.027 14.1 0.3 0.032 13.9 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Amnionless PF14828.1 KUM55743.1 - 0.035 12.6 0.0 0.035 12.6 0.0 1.1 1 0 0 1 1 1 0 Amnionless IncA PF04156.9 KUM55743.1 - 0.038 13.5 0.1 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 IncA protein Rick_17kDa_Anti PF05433.10 KUM55743.1 - 0.039 13.6 7.4 0.081 12.6 5.2 1.5 1 1 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 KUM55743.1 - 0.17 11.5 3.9 0.053 13.1 0.5 1.8 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Podoplanin PF05808.6 KUM55743.1 - 0.35 10.4 6.7 0.89 9.1 4.7 1.7 1 1 0 1 1 1 0 Podoplanin Bacteriocin_IIc PF10439.4 KUM55743.1 - 0.94 9.6 4.3 0.73 10.0 1.9 1.6 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Peptidase_S41 PF03572.13 KUM55744.1 - 7.5e-08 31.9 0.0 1.8e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 Glyco_hydro_72 PF03198.9 KUM55745.1 - 4e-100 334.8 0.0 7.5e-100 333.9 0.0 1.4 2 0 0 2 2 2 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 KUM55745.1 - 0.082 11.7 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Pkinase PF00069.20 KUM55746.1 - 5.4e-10 38.8 0.0 4.1e-09 35.9 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM55746.1 - 3.5e-07 29.5 0.0 6.3e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM55746.1 - 0.027 13.4 0.0 0.06 12.3 0.0 1.4 1 1 0 1 1 1 0 Kinase-like MFS_1 PF07690.11 KUM55749.1 - 1.1e-47 162.4 30.8 1.1e-47 162.4 21.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM55749.1 - 9.3e-10 37.6 13.5 9.3e-10 37.6 9.3 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 KUM55749.1 - 6.9e-05 21.1 6.8 0.13 10.2 0.1 3.4 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family Cytochrom_B558a PF05038.8 KUM55749.1 - 0.055 13.0 0.1 3.4 7.2 0.0 2.6 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit TPMT PF05724.6 KUM55751.1 - 0.00011 21.6 0.0 0.00012 21.6 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) TPMT PF05724.6 KUM55752.1 - 1.4e-13 50.7 0.1 6.2e-13 48.6 0.0 1.8 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_26 PF13659.1 KUM55752.1 - 1.6e-05 24.8 0.0 2e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM55752.1 - 0.00018 22.0 0.0 0.00026 21.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM55752.1 - 0.00038 20.7 0.0 0.0005 20.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM55752.1 - 0.00078 19.0 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM55752.1 - 0.0051 17.2 0.0 0.0069 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 KUM55752.1 - 0.022 13.9 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB N2227 PF07942.7 KUM55752.1 - 0.054 12.4 0.0 0.074 11.9 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein Methyltransf_23 PF13489.1 KUM55752.1 - 0.084 12.5 0.0 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain AdoMet_MTase PF07757.8 KUM55752.1 - 0.098 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Complex1_49kDa PF00346.14 KUM55753.1 - 1.4e-132 440.7 0.0 1.8e-132 440.3 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 KUM55753.1 - 0.18 10.5 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Nickel-dependent hydrogenase RNA_pol_A_bac PF01000.21 KUM55754.1 - 2.1e-28 98.7 0.0 4.1e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KUM55754.1 - 2.1e-13 49.1 0.0 2.8e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain E2_bind PF08825.5 KUM55756.1 - 3.1e-29 100.5 0.0 4.4e-29 100.0 0.0 1.2 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 KUM55756.1 - 1.7e-23 81.9 0.3 4.2e-23 80.6 0.2 1.7 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KUM55756.1 - 1.3e-13 50.1 2.9 1.3e-13 50.1 2.0 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 KUM55756.1 - 7.9e-05 22.1 0.0 0.00015 21.2 0.0 1.4 1 0 0 1 1 1 1 MoeZ/MoeB domain UBA_e1_C PF09358.5 KUM55756.1 - 0.035 14.2 0.0 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain Ecm33 PF12454.3 KUM55756.1 - 0.053 13.4 0.4 0.1 12.5 0.3 1.4 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein DUF2324 PF10086.4 KUM55758.1 - 0.028 13.6 0.0 0.028 13.6 0.0 1.1 1 0 0 1 1 1 0 Putative membrane peptidase family (DUF2324) ABC2_membrane PF01061.19 KUM55759.1 - 6.8e-31 107.0 17.9 6.8e-31 107.0 12.4 2.0 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 KUM55759.1 - 0.0056 15.7 18.3 0.0056 15.7 12.7 1.7 2 1 0 2 2 2 1 ABC-2 family transporter protein PDR_CDR PF06422.7 KUM55759.1 - 0.082 12.5 2.3 0.26 10.9 1.6 1.8 1 0 0 1 1 1 0 CDR ABC transporter PMT PF02366.13 KUM55760.1 - 8.4e-78 261.1 18.8 2.1e-77 259.7 13.1 1.7 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KUM55760.1 - 3e-53 180.1 0.0 6.2e-53 179.1 0.0 1.5 2 0 0 2 2 2 1 MIR domain Ubiquitin_2 PF14560.1 KUM55760.1 - 0.081 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain zf-DHHC PF01529.15 KUM55762.1 - 1.1e-34 119.3 6.1 1.1e-34 119.3 4.2 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase Surp PF01805.15 KUM55764.1 - 4.2e-33 112.7 5.5 2.9e-16 58.8 0.3 2.3 2 0 0 2 2 2 2 Surp module PRP21_like_P PF12230.3 KUM55764.1 - 6e-32 111.0 5.6 8.7e-32 110.4 3.9 1.2 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein rRNA_processing PF08524.6 KUM55764.1 - 0.021 14.5 5.7 0.041 13.6 4.0 1.4 1 0 0 1 1 1 0 rRNA processing DUF4285 PF14113.1 KUM55764.1 - 0.09 12.7 0.1 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4285) DUF1517 PF07466.6 KUM55764.1 - 0.12 11.3 1.3 0.19 10.6 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Tfb4 PF03850.9 KUM55764.1 - 0.17 11.0 0.6 0.25 10.5 0.5 1.1 1 0 0 1 1 1 0 Transcription factor Tfb4 Hemopexin PF00045.14 KUM55765.1 - 1e-13 50.7 3.2 0.0065 16.1 0.0 4.6 4 1 0 4 4 4 4 Hemopexin NUDIX PF00293.23 KUM55766.1 - 4.9e-10 39.1 0.0 5.5e-10 39.0 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain DBC1 PF14443.1 KUM55766.1 - 0.0063 16.0 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 DBC1 ABC_tran PF00005.22 KUM55767.1 - 4.9e-21 75.4 0.0 1.2e-20 74.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KUM55767.1 - 1.1e-05 25.5 0.2 0.00067 19.7 0.1 2.2 1 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KUM55767.1 - 5.1e-05 22.7 0.1 0.00013 21.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 KUM55767.1 - 6.5e-05 23.3 0.2 0.00011 22.6 0.1 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 KUM55767.1 - 0.00015 21.0 0.1 0.0043 16.3 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KUM55767.1 - 0.00021 21.3 0.0 0.00039 20.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 KUM55767.1 - 0.00093 18.6 0.0 0.0019 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KUM55767.1 - 0.0015 18.0 0.4 0.021 14.2 0.1 2.1 2 0 0 2 2 2 1 AAA-like domain DUF258 PF03193.11 KUM55767.1 - 0.0036 16.5 0.0 0.0062 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 cobW PF02492.14 KUM55767.1 - 0.0069 15.8 0.5 0.012 15.0 0.3 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 KUM55767.1 - 0.0069 16.3 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 KUM55767.1 - 0.0089 15.9 0.1 0.024 14.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KUM55767.1 - 0.011 15.8 0.1 0.044 13.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 KUM55767.1 - 0.013 14.5 0.0 0.016 14.2 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 KUM55767.1 - 0.016 14.1 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 KUM55767.1 - 0.017 14.8 0.2 0.051 13.3 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 KUM55767.1 - 0.02 15.0 0.0 0.046 13.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 KUM55767.1 - 0.022 14.5 0.2 0.04 13.7 0.1 1.4 1 0 0 1 1 1 0 Dynamin family Arch_ATPase PF01637.13 KUM55767.1 - 0.024 14.3 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Zeta_toxin PF06414.7 KUM55767.1 - 0.025 13.6 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ABC_membrane PF00664.18 KUM55767.1 - 0.025 13.9 0.6 0.025 13.9 0.4 1.5 2 0 0 2 2 2 0 ABC transporter transmembrane region AAA_17 PF13207.1 KUM55767.1 - 0.031 15.1 0.0 0.057 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.10 KUM55767.1 - 0.032 12.9 0.0 0.054 12.1 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein ABC_ATPase PF09818.4 KUM55767.1 - 0.032 12.8 0.5 0.36 9.3 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class NACHT PF05729.7 KUM55767.1 - 0.082 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain UPF0079 PF02367.12 KUM55767.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Guanylate_kin PF00625.16 KUM55767.1 - 0.15 11.4 0.1 0.28 10.6 0.1 1.3 1 0 0 1 1 1 0 Guanylate kinase Zn_clus PF00172.13 KUM55769.1 - 0.027 14.3 4.2 0.065 13.1 2.9 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.2 KUM55770.1 - 2e-212 688.2 59.5 1.2e-21 76.7 0.2 11.8 2 2 11 13 13 13 13 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KUM55770.1 - 2.2e-147 477.1 42.1 3.2e-11 43.4 0.0 18.8 1 1 19 21 21 21 21 Ankyrin repeats (many copies) Ank PF00023.25 KUM55770.1 - 1.2e-146 469.8 53.0 7.4e-09 34.9 0.1 23.0 25 0 0 25 25 25 21 Ankyrin repeat Ank_5 PF13857.1 KUM55770.1 - 4.5e-99 322.2 35.3 4.1e-07 30.0 0.2 20.4 1 1 21 22 22 22 21 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM55770.1 - 1.6e-98 312.6 0.1 0.00051 20.0 0.0 22.7 22 0 0 22 22 22 21 Ankyrin repeat UBA PF00627.26 KUM55770.1 - 3.8e-07 29.7 5.7 1.6e+02 2.3 0.0 13.4 19 0 0 19 19 19 0 UBA/TS-N domain RHH_2 PF03693.9 KUM55770.1 - 1.3 9.2 0.0 1.3 9.2 0.0 5.9 6 0 0 6 6 6 0 Uncharacterised protein family (UPF0156) DUF1325 PF07039.6 KUM55771.1 - 2.5e-31 107.9 0.0 4e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain TATR PF03430.8 KUM55771.1 - 0.11 11.1 2.9 0.15 10.6 2.0 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator PMI_typeI PF01238.16 KUM55772.1 - 7.7e-145 482.5 0.0 9.2e-145 482.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 KUM55772.1 - 0.0014 18.0 0.1 0.014 14.9 0.1 2.1 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.14 KUM55772.1 - 0.0093 15.6 0.0 2.5 7.7 0.0 2.6 2 0 0 2 2 2 2 AraC-like ligand binding domain DUF3458 PF11940.3 KUM55772.1 - 0.036 12.8 0.1 0.063 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3458) Perilipin PF03036.11 KUM55772.1 - 0.13 11.0 0.1 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Perilipin family Abhydrolase_3 PF07859.8 KUM55773.1 - 1.7e-13 50.6 0.1 2.9e-12 46.6 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KUM55773.1 - 1.8e-12 46.5 0.0 2.3e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KUM55773.1 - 0.058 13.1 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3425 PF11905.3 KUM55774.1 - 4.5e-36 123.7 3.7 8.6e-36 122.8 2.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KUM55774.1 - 0.0033 17.3 2.7 0.0053 16.6 0.9 1.9 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KUM55774.1 - 0.13 12.0 4.2 0.2 11.5 1.1 2.1 1 1 1 2 2 2 0 Basic region leucine zipper GTP_cyclohydro2 PF00925.15 KUM55775.1 - 4.1e-56 188.8 0.0 6e-51 172.0 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II zf-CCHC PF00098.18 KUM55776.1 - 1.2e-11 43.9 9.7 1.9e-05 24.3 0.4 2.5 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 KUM55776.1 - 7.4e-08 31.9 0.4 1.5e-07 30.9 0.2 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 KUM55776.1 - 8.5e-07 28.6 5.3 0.00061 19.4 1.9 2.6 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 KUM55776.1 - 2.7e-05 23.6 0.2 5.7e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_6 PF15288.1 KUM55776.1 - 0.00096 18.7 6.1 0.36 10.5 0.4 2.8 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 KUM55776.1 - 0.0012 18.4 6.0 0.29 10.8 0.5 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 KUM55776.1 - 0.061 12.8 0.1 0.061 12.8 0.1 3.3 2 1 1 3 3 3 0 Zinc knuckle GST_N_3 PF13417.1 KUM55777.1 - 6.3e-14 51.9 0.0 1.1e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KUM55777.1 - 1.9e-12 46.9 0.0 3.8e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KUM55777.1 - 9.9e-12 44.8 0.0 1.7e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KUM55777.1 - 2.3e-09 37.0 0.2 4.4e-09 36.1 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KUM55777.1 - 2e-08 34.1 0.0 3.2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KUM55777.1 - 7.7e-07 29.5 0.0 1.7e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RTA1 PF04479.8 KUM55778.1 - 6e-34 117.4 3.9 7e-34 117.2 2.7 1.0 1 0 0 1 1 1 1 RTA1 like protein DUF4161 PF13722.1 KUM55778.1 - 6.7 7.0 8.8 0.53 10.5 1.7 2.2 1 1 1 2 2 2 0 C-terminal domain on CstA (DUF4161) Tannase PF07519.6 KUM55779.1 - 2.5e-22 79.2 0.2 2.8e-22 79.0 0.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.15 KUM55779.1 - 0.0038 16.8 0.1 0.005 16.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KUM55779.1 - 0.0063 16.4 0.0 0.01 15.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Glyco_hydro_39 PF01229.12 KUM55779.1 - 0.16 10.2 0.0 0.2 9.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 39 Tannase PF07519.6 KUM55780.1 - 5.3e-22 78.1 0.3 6.4e-22 77.9 0.2 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase DUF4050 PF13259.1 KUM55781.1 - 4.9e-40 136.2 0.3 7.8e-40 135.6 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) AAA PF00004.24 KUM55782.1 - 9.5e-40 135.8 0.1 1.7e-37 128.5 0.0 3.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KUM55782.1 - 2.1e-05 24.5 0.4 0.003 17.5 0.3 3.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KUM55782.1 - 7.5e-05 22.8 1.0 0.0029 17.7 0.0 3.4 3 1 0 3 3 3 1 AAA domain RuvB_N PF05496.7 KUM55782.1 - 0.00012 21.1 0.0 0.00026 20.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 KUM55782.1 - 0.00019 20.2 0.1 0.00061 18.6 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus AAA_5 PF07728.9 KUM55782.1 - 0.00085 19.0 0.0 0.0028 17.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KUM55782.1 - 0.0009 20.0 0.1 0.0036 18.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KUM55782.1 - 0.0011 18.8 0.1 0.0064 16.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KUM55782.1 - 0.0016 18.1 1.0 0.0038 16.9 0.2 2.0 2 0 0 2 2 1 1 Part of AAA domain IstB_IS21 PF01695.12 KUM55782.1 - 0.0044 16.4 0.0 0.0098 15.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 KUM55782.1 - 0.0063 16.4 0.1 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KUM55782.1 - 0.008 16.0 0.0 0.05 13.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KUM55782.1 - 0.017 14.3 0.0 0.037 13.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KUM55782.1 - 0.026 14.6 0.0 0.075 13.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase SHQ1 PF04925.10 KUM55782.1 - 0.031 13.7 0.0 0.074 12.4 0.0 1.6 1 0 0 1 1 1 0 SHQ1 protein AAA_24 PF13479.1 KUM55782.1 - 0.055 13.0 0.2 0.15 11.6 0.2 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KUM55782.1 - 0.065 13.5 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF1951 PF09188.5 KUM55782.1 - 0.086 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1951) PhoH PF02562.11 KUM55782.1 - 0.2 10.8 0.9 0.81 8.8 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein Sld5 PF05916.6 KUM55783.1 - 5.7e-12 45.8 0.0 8.9e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein Sulfate_transp PF00916.15 KUM55785.1 - 5.6e-43 146.9 9.6 1.1e-42 146.0 6.6 1.5 1 0 0 1 1 1 1 Sulfate transporter family STAS PF01740.16 KUM55785.1 - 4.7e-11 42.1 0.0 8.9e-11 41.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain Uma2 PF05685.7 KUM55786.1 - 0.00083 18.7 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 Putative restriction endonuclease Fimbrillin_C PF15495.1 KUM55789.1 - 0.015 15.4 0.0 0.016 15.3 0.0 1.0 1 0 0 1 1 1 0 Major fimbrial subunit protein type IV, Fimbrillin, C-terminal Mitoc_L55 PF09776.4 KUM55789.1 - 0.17 11.4 3.5 0.17 11.4 2.4 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 SM-ATX PF14438.1 KUM55789.1 - 0.27 11.1 2.1 0.31 10.9 1.5 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain BLVR PF06375.6 KUM55789.1 - 0.28 11.0 18.2 0.26 11.0 12.6 1.0 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) OAD_gamma PF04277.8 KUM55789.1 - 0.44 10.9 3.0 0.42 11.0 2.1 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF788 PF05620.6 KUM55789.1 - 1.3 8.8 7.0 1.3 8.8 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Casc1 PF12366.3 KUM55789.1 - 1.7 8.0 6.8 1.6 8.1 4.7 1.0 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 DUF3464 PF11947.3 KUM55789.1 - 1.8 7.9 5.1 1.8 8.0 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) ETRAMP PF09716.5 KUM55789.1 - 1.9 8.4 9.8 2.1 8.3 6.8 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) SHR3_chaperone PF08229.6 KUM55789.1 - 2.9 6.7 6.0 2.8 6.8 4.2 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 ERK-JNK_inhib PF15002.1 KUM55789.1 - 7.4 5.8 15.2 7.6 5.8 10.5 1.1 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor Peptidase_S49_N PF08496.5 KUM55789.1 - 7.5 6.3 14.6 7.9 6.2 10.1 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal zf-H2C2_2 PF13465.1 KUM55791.1 - 1.3e-09 37.8 17.5 7.5e-06 25.9 2.3 3.9 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 KUM55791.1 - 6.3e-08 32.5 16.5 0.00091 19.4 1.3 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KUM55791.1 - 8.1e-05 22.6 16.7 0.009 16.2 1.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KUM55791.1 - 2.3 8.4 7.7 0.27 11.4 0.2 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF188 PF02639.9 KUM55792.1 - 0.49 9.8 2.6 0.69 9.3 1.8 1.1 1 0 0 1 1 1 0 Uncharacterized BCR, YaiI/YqxD family COG1671 RVT_1 PF00078.22 KUM55793.1 - 1.2e-25 90.1 0.0 2.4e-25 89.1 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1987 PF09345.5 KUM55793.1 - 0.088 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) MFS_1 PF07690.11 KUM55794.1 - 2.5e-24 85.6 64.9 1.2e-20 73.5 29.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 KUM55794.1 - 7.5e-05 21.3 15.7 7.5e-05 21.3 10.9 2.7 1 1 1 2 2 2 1 Vacuole effluxer Atg22 like Tub_2 PF04525.7 KUM55795.1 - 9.2e-06 25.1 0.0 2.8e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Tubby C 2 NUDIX PF00293.23 KUM55797.1 - 9.4e-17 60.9 0.1 1.2e-16 60.5 0.1 1.3 1 1 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 KUM55797.1 - 0.083 12.3 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 NUDIX domain adh_short PF00106.20 KUM55798.1 - 3.4e-21 75.8 0.0 6.2e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM55798.1 - 5.3e-07 29.4 0.1 3.5e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KUM55798.1 - 1.9e-05 24.5 0.0 2.7e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KUM55798.1 - 4.6e-05 22.9 0.0 8.9e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KUM55798.1 - 8.5e-05 22.6 0.0 0.00019 21.4 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KUM55798.1 - 0.0015 17.4 0.0 0.0033 16.3 0.0 1.4 2 0 0 2 2 2 1 RmlD substrate binding domain TrkA_N PF02254.13 KUM55798.1 - 0.0062 16.5 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_4 PF07993.7 KUM55798.1 - 0.029 13.2 0.3 2 7.2 0.0 2.6 2 1 1 3 3 3 0 Male sterility protein 3Beta_HSD PF01073.14 KUM55798.1 - 0.044 12.4 0.0 0.064 11.9 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KUM55798.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 KUM55798.1 - 0.14 11.1 0.0 0.24 10.3 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase Hemerythrin PF01814.18 KUM55799.1 - 3.1e-09 37.0 0.1 4.4e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain p450 PF00067.17 KUM55800.1 - 5.9e-69 232.7 0.0 7.2e-69 232.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADP_ribosyl_GH PF03747.9 KUM55802.1 - 4e-55 187.6 0.2 4.6e-55 187.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase NmrA PF05368.8 KUM55803.1 - 4.3e-12 45.7 0.0 5.7e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KUM55803.1 - 0.00063 19.8 0.0 0.00091 19.2 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Chorismate_bind PF00425.13 KUM55804.1 - 2.7e-89 298.8 0.0 3.6e-89 298.5 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 KUM55804.1 - 2.3e-29 102.1 0.1 1.2e-26 93.3 0.0 2.8 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region Methyltransf_2 PF00891.13 KUM55805.1 - 4.3e-27 94.8 0.0 6.1e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KUM55805.1 - 9.2e-05 22.9 0.0 0.00033 21.2 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KUM55805.1 - 0.00028 20.3 0.0 0.00071 18.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 KUM55805.1 - 0.0048 17.3 0.0 0.031 14.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM55805.1 - 0.0091 16.3 0.0 0.029 14.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 KUM55805.1 - 0.026 14.0 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) A2M_recep PF07677.9 KUM55805.1 - 0.034 14.3 0.1 14 5.9 0.0 2.6 2 0 0 2 2 2 0 A-macroglobulin receptor Methyltransf_31 PF13847.1 KUM55805.1 - 0.051 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.10 KUM55805.1 - 0.091 11.8 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Sec3-PIP2_bind PF15277.1 KUM55805.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH Ubie_methyltran PF01209.13 KUM55805.1 - 0.14 11.2 0.0 0.33 10.0 0.0 1.6 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KUM55805.1 - 0.15 12.1 0.0 0.47 10.4 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain AA_permease PF00324.16 KUM55806.1 - 3.8e-131 437.7 49.7 4.6e-131 437.4 34.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KUM55806.1 - 4.9e-33 114.3 55.5 6.2e-33 113.9 38.4 1.1 1 0 0 1 1 1 1 Amino acid permease AMP-binding PF00501.23 KUM55808.1 - 7.3e-78 261.8 0.0 9.5e-78 261.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme GST_N_3 PF13417.1 KUM55809.1 - 1.7e-12 47.3 0.1 3.3e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KUM55809.1 - 1.3e-09 37.9 0.0 2.2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KUM55809.1 - 0.0028 17.5 0.0 0.0059 16.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KUM55809.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain EF-hand_4 PF12763.2 KUM55810.1 - 1.8e-36 124.0 0.0 1.9e-14 53.2 0.0 4.0 4 0 0 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 KUM55810.1 - 6.9e-10 38.9 0.0 5.3e-06 26.4 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 KUM55810.1 - 4.6e-06 25.5 0.1 0.0017 17.5 0.0 4.5 5 0 0 5 5 5 1 EF hand UBA PF00627.26 KUM55810.1 - 9.1e-06 25.3 0.0 2e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_8 PF13833.1 KUM55810.1 - 3.7e-05 23.2 0.0 0.0058 16.2 0.0 3.7 4 0 0 4 4 4 1 EF-hand domain pair GAS PF13851.1 KUM55810.1 - 0.00011 21.5 21.3 0.002 17.3 7.2 2.2 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Macoilin PF09726.4 KUM55810.1 - 0.00032 19.1 8.6 0.00063 18.1 6.0 1.4 1 0 0 1 1 1 1 Transmembrane protein EF-hand_6 PF13405.1 KUM55810.1 - 0.001 18.7 0.5 1.8 8.6 0.0 5.0 5 0 0 5 5 5 1 EF-hand domain WEMBL PF05701.6 KUM55810.1 - 0.0022 16.5 20.3 0.0031 16.0 14.1 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Myosin_tail_1 PF01576.14 KUM55810.1 - 0.0049 14.6 23.0 0.0073 14.1 15.9 1.2 1 0 0 1 1 1 1 Myosin tail TPR_MLP1_2 PF07926.7 KUM55810.1 - 0.011 15.5 28.1 0.042 13.5 12.0 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein EF-hand_5 PF13202.1 KUM55810.1 - 0.027 13.7 0.4 0.093 12.1 0.0 2.1 2 0 0 2 2 1 0 EF hand Spc7 PF08317.6 KUM55810.1 - 0.057 12.0 22.6 0.11 11.1 7.2 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF812 PF05667.6 KUM55810.1 - 0.074 11.5 21.3 0.051 12.0 12.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Exonuc_VII_L PF02601.10 KUM55810.1 - 0.17 11.0 13.7 0.26 10.4 9.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit MAD PF05557.8 KUM55810.1 - 0.22 9.5 21.0 0.33 9.0 14.5 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein COG2 PF06148.6 KUM55810.1 - 0.25 11.2 10.9 2.9 7.7 2.1 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 IncA PF04156.9 KUM55810.1 - 0.32 10.5 25.6 0.29 10.7 8.6 2.2 1 1 1 2 2 2 0 IncA protein DUF3584 PF12128.3 KUM55810.1 - 0.62 7.3 25.1 0.86 6.8 17.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 KUM55810.1 - 1.2 8.2 10.6 0.93 8.6 1.9 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 KUM55810.1 - 1.4 8.7 24.6 0.25 11.1 2.8 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.3 KUM55810.1 - 1.9 8.3 30.4 0.92 9.3 10.0 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Mod_r PF07200.8 KUM55810.1 - 2.4 8.0 23.3 0.09 12.6 8.8 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein APG6 PF04111.7 KUM55810.1 - 3.3 6.6 25.2 0.78 8.7 14.5 2.0 1 1 2 3 3 3 0 Autophagy protein Apg6 TMF_TATA_bd PF12325.3 KUM55810.1 - 4 7.1 22.0 2.5 7.8 2.4 3.6 1 1 4 5 5 5 0 TATA element modulatory factor 1 TATA binding Fib_alpha PF08702.5 KUM55810.1 - 6.2 6.9 19.9 0.63 10.1 8.0 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FUSC PF04632.7 KUM55810.1 - 8.3 4.6 7.1 13 4.0 4.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family V_ATPase_I PF01496.14 KUM55810.1 - 9 4.0 9.4 14 3.3 6.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GST_C PF00043.20 KUM55811.1 - 1.7e-07 31.1 0.0 2.7e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KUM55811.1 - 5.9e-07 29.5 0.0 1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KUM55811.1 - 1.1e-06 29.0 0.0 2.4e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KUM55811.1 - 3.5e-05 23.9 0.0 7.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KUM55811.1 - 0.00034 20.4 0.0 0.0015 18.3 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CFEM PF05730.6 KUM55812.1 - 0.00075 19.2 6.3 0.0016 18.2 4.4 1.6 1 1 0 1 1 1 1 CFEM domain DUF1993 PF09351.5 KUM55813.1 - 2.5e-42 144.5 0.0 2.9e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) TMEMspv1-c74-12 PF11044.3 KUM55814.1 - 0.0085 15.6 0.2 0.015 14.8 0.1 1.3 1 0 0 1 1 1 1 Plectrovirus spv1-c74 ORF 12 transmembrane protein UCH PF00443.24 KUM55816.1 - 3.6e-65 219.7 0.0 5.5e-65 219.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 KUM55816.1 - 4.2e-11 43.1 0.0 2.3e-10 40.7 0.0 2.3 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.1 KUM55816.1 - 6e-11 42.3 0.0 0.0002 20.8 0.0 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Abi PF02517.11 KUM55822.1 - 4.3e-12 46.0 14.6 2.4e-11 43.6 10.2 2.4 1 1 0 1 1 1 1 CAAX protease self-immunity zf-Mss51 PF13824.1 KUM55823.1 - 9.2e-29 99.0 6.8 1.9e-28 98.0 4.7 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KUM55823.1 - 0.015 15.1 0.3 0.015 15.1 0.2 1.8 2 0 0 2 2 2 0 MYND finger DUF3011 PF11218.3 KUM55823.1 - 0.04 13.7 0.1 0.063 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3011) Oxysterol_BP PF01237.13 KUM55824.1 - 1.4e-130 434.9 0.1 5.7e-130 432.9 0.0 1.9 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.1 KUM55824.1 - 3e-16 59.0 1.4 9.5e-11 41.5 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 KUM55824.1 - 2.6e-15 56.5 0.0 1.7e-09 37.8 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KUM55824.1 - 2.1e-14 52.5 0.1 6.3e-05 22.5 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 KUM55824.1 - 8.6e-14 50.2 0.0 0.00017 21.5 0.0 4.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KUM55824.1 - 6.6e-12 45.6 0.3 6.2e-06 26.5 0.0 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PH PF00169.24 KUM55824.1 - 2.3e-10 40.6 0.2 5e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KUM55824.1 - 2.6e-08 34.0 1.2 7.2e-08 32.6 0.8 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 KUM55824.1 - 6.9e-07 29.2 0.9 2.1e-06 27.7 0.6 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain SGL PF08450.7 KUM55827.1 - 5.5e-24 84.8 1.0 1.6e-23 83.4 0.7 1.8 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 KUM55827.1 - 2e-05 24.4 0.1 0.00022 21.1 0.1 2.4 1 1 1 2 2 2 1 Arylesterase Str_synth PF03088.11 KUM55827.1 - 3.7e-05 23.6 0.0 9.9e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 Strictosidine synthase YmzC PF14157.1 KUM55827.1 - 0.058 13.2 0.1 1.9 8.3 0.0 2.8 3 0 0 3 3 3 0 YmzC-like protein SKG6 PF08693.5 KUM55828.1 - 3.1e-05 23.2 0.1 6e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Yip1 PF04893.12 KUM55828.1 - 0.0023 17.4 0.1 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 Yip1 domain Beta-APP PF03494.8 KUM55828.1 - 0.56 9.7 3.7 1.1 8.8 2.6 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) HSBP1 PF06825.7 KUM55829.1 - 0.01 15.4 2.8 7.5 6.2 1.9 3.4 1 1 0 1 1 1 1 Heat shock factor binding protein 1 Clathrin PF00637.15 KUM55829.1 - 0.065 12.8 0.7 7.7 6.1 0.1 2.2 1 1 1 2 2 2 0 Region in Clathrin and VPS MRP_L53 PF10780.4 KUM55829.1 - 0.087 12.8 3.5 8 6.5 0.3 3.3 1 1 2 3 3 3 0 39S ribosomal protein L53/MRP-L53 LUC7 PF03194.10 KUM55829.1 - 0.49 9.8 4.2 0.62 9.5 2.9 1.1 1 0 0 1 1 1 0 LUC7 N_terminus XhlA PF10779.4 KUM55829.1 - 3.1 7.7 6.1 1.5e+02 2.3 3.9 2.9 1 1 0 1 1 1 0 Haemolysin XhlA DUF3328 PF11807.3 KUM55830.1 - 1.4e-36 126.2 0.1 1.8e-36 125.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DDE_3 PF13358.1 KUM55831.1 - 7.2e-32 110.1 0.0 2.4e-31 108.4 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_1 PF03184.14 KUM55831.1 - 3.8e-11 42.5 0.0 3.2e-10 39.5 0.0 2.2 3 0 0 3 3 3 1 DDE superfamily endonuclease rve PF00665.21 KUM55831.1 - 1.4e-07 31.6 0.0 5.8e-07 29.6 0.0 2.1 3 0 0 3 3 3 1 Integrase core domain HTH_29 PF13551.1 KUM55831.1 - 2.8e-05 24.2 0.0 0.00013 22.1 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 KUM55831.1 - 9.9e-05 23.0 0.0 0.0003 21.5 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_33 PF13592.1 KUM55831.1 - 0.00029 20.3 0.0 0.0037 16.7 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn helix DDE_Tnp_ISAZ013 PF07592.6 KUM55831.1 - 0.012 14.4 0.1 0.93 8.1 0.0 2.2 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain HTH_Crp_2 PF13545.1 KUM55831.1 - 0.091 12.5 0.9 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain ERAP1_C PF11838.3 KUM55833.1 - 7.4e-78 262.0 0.9 9.3e-78 261.7 0.6 1.1 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.15 KUM55834.1 - 2.9e-118 395.3 0.4 3.5e-118 395.0 0.3 1.0 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 KUM55834.1 - 1.3e-13 51.0 4.3 2.6e-13 50.1 3.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily WD40 PF00400.27 KUM55836.1 - 3.5e-08 33.0 10.0 0.00031 20.5 0.1 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat Mito_carr PF00153.22 KUM55837.1 - 3.4e-53 177.3 2.5 9.6e-18 63.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein AphA_like PF14557.1 KUM55837.1 - 0.0018 17.8 0.0 0.0035 16.9 0.0 1.5 1 0 0 1 1 1 1 Putative AphA-like transcriptional regulator Abhydrolase_6 PF12697.2 KUM55839.1 - 2.3e-20 73.4 0.6 3.1e-20 73.0 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM55839.1 - 2.8e-12 46.6 0.0 5e-12 45.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM55839.1 - 5.4e-09 35.9 0.0 8.5e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold adh_short PF00106.20 KUM55840.1 - 1.3e-18 67.4 0.3 1.6e-18 67.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM55840.1 - 2.3e-09 37.1 0.1 3.3e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KUM55840.1 - 1.2e-07 31.8 0.0 1.4e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Peripla_BP_5 PF13433.1 KUM55840.1 - 0.062 12.0 0.0 0.089 11.5 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein domain F420_oxidored PF03807.12 KUM55840.1 - 0.064 13.6 0.1 1.3 9.4 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Ank_4 PF13637.1 KUM55841.1 - 0.13 12.8 0.1 0.28 11.7 0.0 1.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Peptidase_C70 PF12385.3 KUM55841.1 - 0.14 11.8 0.3 6.1 6.5 0.0 2.1 1 1 1 2 2 2 0 Papain-like cysteine protease AvrRpt2 Epimerase PF01370.16 KUM55842.1 - 2.9e-17 62.8 0.0 1.3e-16 60.7 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KUM55842.1 - 2.3e-15 57.0 0.1 3.3e-15 56.5 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KUM55842.1 - 7.8e-15 54.3 0.0 1.6e-14 53.2 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KUM55842.1 - 5.5e-09 35.3 0.0 1.2e-07 30.9 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 KUM55842.1 - 2.3e-06 26.7 0.0 4.5e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 KUM55842.1 - 1.4e-05 24.5 0.0 2.3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KUM55842.1 - 0.00047 20.1 0.0 0.00096 19.1 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.13 KUM55842.1 - 0.052 13.1 0.0 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 KUM55842.1 - 0.066 12.0 0.0 0.44 9.3 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain JAB PF01398.16 KUM55843.1 - 2.5e-28 98.1 0.0 6.3e-28 96.8 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KUM55843.1 - 2.9e-07 30.0 0.0 5.1e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain GBP_repeat PF02526.9 KUM55843.1 - 0.066 12.6 0.2 0.066 12.6 0.1 1.8 2 0 0 2 2 2 0 Glycophorin-binding protein RasGEF PF00617.14 KUM55844.1 - 1.1e-63 214.3 0.0 2e-63 213.5 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KUM55844.1 - 3.8e-29 100.8 0.6 9.8e-29 99.5 0.4 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 KUM55844.1 - 4e-15 54.9 0.2 4e-15 54.9 0.1 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KUM55844.1 - 1.5e-13 50.1 0.1 4.4e-13 48.5 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KUM55844.1 - 7.6e-10 38.1 0.1 2.2e-09 36.6 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain WW PF00397.21 KUM55844.1 - 0.0017 18.1 0.0 0.004 16.9 0.0 1.6 1 0 0 1 1 1 1 WW domain Ashwin PF15323.1 KUM55844.1 - 0.034 14.1 1.2 0.077 12.9 0.8 1.5 1 0 0 1 1 1 0 Developmental protein MAP65_ASE1 PF03999.7 KUM55845.1 - 3e-74 250.7 1.5 6e-74 249.7 1.0 1.5 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Prominin PF05478.6 KUM55845.1 - 0.058 10.9 0.8 0.13 9.8 0.5 1.5 2 0 0 2 2 2 0 Prominin AIPR PF10592.4 KUM55845.1 - 0.1 11.8 0.2 0.19 11.0 0.2 1.3 1 0 0 1 1 1 0 AIPR protein HAUS-augmin3 PF14932.1 KUM55845.1 - 0.16 11.1 11.2 1.6 7.8 1.9 2.8 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 PEP-utilisers_N PF05524.8 KUM55845.1 - 1.1 9.0 8.0 3.4 7.4 0.3 3.1 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal LTXXQ PF07813.7 KUM55845.1 - 1.2 9.6 6.9 2.7 8.5 0.2 3.4 3 0 0 3 3 3 0 LTXXQ motif family protein MFS_1 PF07690.11 KUM55847.1 - 5.9e-30 104.1 37.8 6.6e-30 104.0 24.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KUM55847.1 - 0.089 12.8 10.1 0.13 12.3 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) NfeD PF01957.13 KUM55847.1 - 0.47 10.5 9.2 0.48 10.5 0.0 3.4 2 1 0 3 3 3 0 NfeD-like C-terminal, partner-binding Gly_acyl_tr_C PF08444.5 KUM55848.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region FAD_binding_3 PF01494.14 KUM55849.1 - 3.3e-20 72.4 0.0 4.3e-09 35.9 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 KUM55849.1 - 0.0076 16.3 0.0 0.094 12.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM55849.1 - 0.014 15.3 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_Gly3P_dh_N PF01210.18 KUM55849.1 - 0.075 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SE PF08491.5 KUM55849.1 - 0.11 11.3 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Thi4 PF01946.12 KUM55849.1 - 0.19 10.8 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 KUM55849.1 - 0.19 10.1 0.0 0.31 9.4 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Aminotran_1_2 PF00155.16 KUM55850.1 - 1.5e-47 162.3 0.0 1.8e-47 162.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II adh_short PF00106.20 KUM55851.1 - 1.1e-26 93.7 0.0 1.6e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM55851.1 - 1.3e-25 90.5 0.0 1.6e-25 90.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM55851.1 - 1e-07 31.7 0.0 1.8e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 KR domain OTU PF02338.14 KUM55852.1 - 2e-16 60.6 2.9 3.7e-16 59.8 0.2 2.4 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KUM55852.1 - 4.4e-07 29.5 0.2 0.00011 21.5 0.0 2.5 3 0 0 3 3 3 2 Peptidase C65 Otubain Cep57_MT_bd PF06657.8 KUM55852.1 - 0.05 13.5 3.7 0.14 12.1 2.6 1.8 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Menin PF05053.8 KUM55852.1 - 0.34 9.0 4.1 0.41 8.7 2.8 1.2 1 0 0 1 1 1 0 Menin DUF3275 PF11679.3 KUM55852.1 - 7.5 6.1 14.8 6 6.4 8.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3275) ICL PF00463.16 KUM55853.1 - 6.8e-286 948.5 4.0 7.8e-286 948.3 2.8 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KUM55853.1 - 3.2e-12 46.2 0.1 9.3e-12 44.6 0.0 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase PT-TG PF14449.1 KUM55853.1 - 0.07 12.9 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 Pre-toxin TG Trehalase PF01204.13 KUM55854.1 - 3.3e-190 633.1 0.1 3.9e-190 632.8 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 KUM55854.1 - 5e-17 60.9 0.3 8.9e-17 60.1 0.2 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain DUF1882 PF08966.6 KUM55858.1 - 0.15 12.0 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1882) Ribosomal_S28e PF01200.13 KUM55859.1 - 2.9e-33 113.4 2.2 3.7e-33 113.0 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e HisG PF01634.13 KUM55860.1 - 7.9e-51 171.8 0.4 1.6e-50 170.8 0.1 1.6 2 0 0 2 2 2 1 ATP phosphoribosyltransferase HisG_C PF08029.6 KUM55860.1 - 6.1e-28 96.5 0.2 1.4e-27 95.4 0.1 1.7 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 KUM55860.1 - 0.0016 18.0 0.1 0.0026 17.3 0.1 1.3 1 0 0 1 1 1 1 NMT1/THI5 like Fungal_trans PF04082.13 KUM55863.1 - 9.7e-16 57.4 3.7 1.8e-15 56.5 2.5 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KUM55864.1 - 0.0065 15.2 1.3 0.0074 15.0 0.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 KUM55865.1 - 5.4e-32 110.8 30.4 5.4e-32 110.8 21.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1129 PF06570.6 KUM55865.1 - 0.29 10.3 0.0 0.29 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) WH2 PF02205.15 KUM55866.1 - 6.4e-12 44.6 0.4 8.8e-12 44.2 0.3 1.2 1 0 0 1 1 1 1 WH2 motif CAP_N PF01213.14 KUM55866.1 - 2.7 7.1 4.8 2.9 7.0 3.3 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ABC_tran PF00005.22 KUM55867.1 - 1.7e-47 161.1 0.0 2.3e-27 95.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KUM55867.1 - 6e-44 150.4 39.3 8.2e-30 104.1 10.1 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 KUM55867.1 - 3.2e-06 26.5 0.0 0.0071 15.5 0.0 3.1 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KUM55867.1 - 0.00047 20.2 0.8 0.087 12.7 0.0 3.2 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.1 KUM55867.1 - 0.00072 19.0 0.7 0.092 12.1 0.1 3.1 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 KUM55867.1 - 0.0015 18.4 0.1 0.29 11.0 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KUM55867.1 - 0.0015 18.9 0.3 0.45 11.0 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 KUM55867.1 - 0.0027 17.2 0.1 0.29 10.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF87 PF01935.12 KUM55867.1 - 0.0071 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_17 PF13207.1 KUM55867.1 - 0.0082 16.9 0.2 3.2 8.5 0.1 2.8 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 KUM55867.1 - 0.027 13.6 0.1 1.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_30 PF13604.1 KUM55867.1 - 0.034 13.7 0.3 15 5.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 KUM55867.1 - 0.096 11.7 0.0 8.7 5.3 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin SbcCD_C PF13558.1 KUM55867.1 - 0.1 12.5 0.8 1.7 8.6 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.18 KUM55867.1 - 0.1 12.3 0.6 5.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Dynamin family AAA_16 PF13191.1 KUM55867.1 - 0.15 12.0 4.6 2.8 7.8 0.5 2.9 2 2 0 2 2 2 0 AAA ATPase domain DUF3445 PF11927.3 KUM55870.1 - 5.2e-47 160.3 0.1 5.8e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF3445 PF11927.3 KUM55871.1 - 1.8e-14 53.7 0.0 2.5e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) 4HBT_3 PF13622.1 KUM55872.1 - 7.2e-43 147.1 0.1 1e-42 146.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KUM55872.1 - 2.5e-23 82.1 0.0 1.9e-12 46.9 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase Abhydrolase_6 PF12697.2 KUM55873.1 - 0.042 13.7 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Amidase PF01425.16 KUM55874.1 - 2.7e-37 128.6 0.8 1.5e-34 119.6 0.3 2.1 2 0 0 2 2 2 2 Amidase C-C_Bond_Lyase PF15617.1 KUM55874.1 - 0.29 9.9 0.0 0.97 8.1 0.0 1.7 2 0 0 2 2 2 0 C-C_Bond_Lyase of the TIM-Barrel fold Zn_clus PF00172.13 KUM55875.1 - 0.00067 19.5 8.7 0.0012 18.6 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAHP_synth_1 PF00793.15 KUM55876.1 - 1.1e-93 312.9 0.0 1.3e-93 312.6 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family COX14 PF14880.1 KUM55877.1 - 8.6e-19 66.9 0.2 8.6e-19 66.9 0.1 2.1 2 0 0 2 2 2 1 Cytochrome oxidase c assembly ECM11 PF15463.1 KUM55877.1 - 0.00027 21.2 0.4 0.0016 18.6 0.0 2.1 2 0 0 2 2 2 1 Extracellular mutant protein 11 DUF2458 PF10454.4 KUM55878.1 - 1.7e-46 157.8 0.1 2.4e-46 157.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) THOC7 PF05615.8 KUM55878.1 - 0.037 14.2 0.0 0.12 12.6 0.0 1.8 1 1 1 2 2 2 0 Tho complex subunit 7 RIC3 PF15361.1 KUM55878.1 - 1.8 8.8 0.0 1.8 8.8 0.0 2.6 2 1 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 MFS_1 PF07690.11 KUM55879.1 - 2.5e-35 121.8 20.6 2.1e-34 118.8 13.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 KUM55880.1 - 1e-10 40.9 1.7 1.1e-10 40.8 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain G_glu_transpept PF01019.16 KUM55881.1 - 1.3e-45 155.8 0.0 1.7e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase SET PF00856.23 KUM55883.1 - 7.5e-08 32.8 2.5 4.9e-07 30.1 0.1 3.1 3 1 0 3 3 3 1 SET domain PHD PF00628.24 KUM55883.1 - 4.6e-06 26.2 9.3 8.4e-06 25.3 6.5 1.5 1 0 0 1 1 1 1 PHD-finger CDC73 PF05179.9 KUM55884.1 - 4.7e-43 147.5 0.5 1.9e-42 145.5 0.1 2.1 2 1 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family MFS_1 PF07690.11 KUM55885.1 - 5.8e-09 35.1 22.2 5.8e-09 35.1 15.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Nuc_H_symport PF03825.11 KUM55885.1 - 0.00012 21.0 3.0 0.00014 20.8 2.1 1.2 1 0 0 1 1 1 1 Nucleoside H+ symporter RGS PF00615.14 KUM55886.1 - 2e-34 118.2 0.1 4.3e-34 117.1 0.1 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 KUM55886.1 - 1.4e-23 82.4 0.1 1.2e-17 63.3 0.0 3.2 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Glyco_tran_WbsX PF14307.1 KUM55886.1 - 0.066 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase WbsX ELO PF01151.13 KUM55891.1 - 3.6e-85 285.2 7.8 4.4e-85 284.9 5.4 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Na_H_Exchanger PF00999.16 KUM55893.1 - 3.4e-40 137.7 23.2 6.5e-40 136.8 16.0 1.4 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family HET-s_218-289 PF11558.3 KUM55894.1 - 0.18 11.8 0.3 1 9.3 0.0 2.3 3 0 0 3 3 3 0 Het-s 218-289 Colicin-DNase PF12639.2 KUM55895.1 - 0.008 16.4 1.7 0.79 9.9 0.3 2.5 1 1 1 2 2 2 2 DNase/tRNase domain of colicin-like bacteriocin MT0933_antitox PF14013.1 KUM55895.1 - 5.8 7.1 18.9 1.7e+02 2.3 0.1 5.7 2 1 1 4 4 4 0 MT0933-like antitoxin protein Abhydrolase_6 PF12697.2 KUM55896.1 - 5.9e-07 29.6 0.9 7.7e-07 29.2 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM55896.1 - 7.8e-07 28.9 0.0 1.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KUM55896.1 - 0.00055 20.2 2.0 0.00064 20.0 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain UPF0227 PF05728.7 KUM55896.1 - 0.0019 17.9 0.1 0.0044 16.7 0.1 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) PGAP1 PF07819.8 KUM55896.1 - 0.0021 17.6 0.0 0.0047 16.5 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 KUM55896.1 - 0.0062 16.1 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 KUM55896.1 - 0.014 15.0 0.0 0.041 13.4 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) DUF2305 PF10230.4 KUM55896.1 - 0.017 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_1 PF00561.15 KUM55896.1 - 0.021 14.3 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.3 KUM55896.1 - 0.024 14.0 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF676 PF05057.9 KUM55896.1 - 0.052 12.8 0.0 0.096 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Mitofilin PF09731.4 KUM55896.1 - 0.37 9.3 15.3 0.55 8.8 10.6 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein NARP1 PF12569.3 KUM55896.1 - 0.63 8.7 12.4 0.98 8.0 8.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Uso1_p115_head PF04869.9 KUM55897.1 - 3.4e-105 351.2 0.0 8.6e-105 349.9 0.0 1.8 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region TMF_DNA_bd PF12329.3 KUM55897.1 - 2.5e-11 43.2 37.8 1.3e-08 34.5 8.1 9.6 2 2 9 11 11 7 3 TATA element modulatory factor 1 DNA binding Uso1_p115_C PF04871.8 KUM55897.1 - 1.3e-06 28.3 31.0 1.3e-06 28.3 21.5 5.4 1 1 4 5 5 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region Filament PF00038.16 KUM55897.1 - 2.9e-05 23.6 79.9 0.0034 16.9 12.2 5.2 1 1 3 4 4 4 2 Intermediate filament protein AAA_13 PF13166.1 KUM55897.1 - 0.0003 19.4 27.8 0.0003 19.4 19.2 3.2 1 1 2 3 3 3 2 AAA domain Tropomyosin_1 PF12718.2 KUM55897.1 - 0.0032 17.3 18.4 0.0032 17.3 12.8 6.1 1 1 4 5 5 4 1 Tropomyosin like Tropomyosin PF00261.15 KUM55897.1 - 0.0051 15.9 3.1 0.0051 15.9 2.1 5.9 1 1 4 5 5 4 3 Tropomyosin CENP-F_leu_zip PF10473.4 KUM55897.1 - 0.0079 16.0 15.9 0.0079 16.0 11.0 5.3 2 1 2 5 5 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Surfac_D-trimer PF09006.6 KUM55897.1 - 0.018 14.7 16.8 2.5 7.8 0.1 7.1 6 1 1 7 7 7 0 Lung surfactant protein D coiled-coil trimerisation Myosin_tail_1 PF01576.14 KUM55897.1 - 0.018 12.7 89.1 0.04 11.6 24.3 2.5 1 1 1 2 2 2 0 Myosin tail DUF3584 PF12128.3 KUM55897.1 - 0.04 11.2 87.3 0.0093 13.3 32.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.5 KUM55897.1 - 0.13 12.4 63.0 0.41 10.7 6.7 5.4 1 1 4 5 5 5 0 Fibrinogen alpha/beta chain family Reo_sigmaC PF04582.7 KUM55897.1 - 1.2 8.2 46.5 0.048 12.8 1.4 4.6 2 1 3 5 5 5 0 Reovirus sigma C capsid protein AIP3 PF03915.8 KUM55897.1 - 1.3 7.8 66.3 0.0072 15.2 9.9 3.5 1 1 2 3 3 3 0 Actin interacting protein 3 Spc7 PF08317.6 KUM55897.1 - 6 5.4 78.6 0.04 12.5 14.0 4.6 1 1 3 4 4 4 0 Spc7 kinetochore protein XRN_N PF03159.13 KUM55898.1 - 2.6e-106 354.3 1.6 5.9e-106 353.1 0.0 2.0 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 KUM55898.1 - 0.0096 15.8 1.5 0.02 14.7 1.1 1.6 1 0 0 1 1 1 1 Zinc knuckle YTH PF04146.10 KUM55899.1 - 7.1e-57 190.9 0.0 1e-56 190.4 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain RRM_6 PF14259.1 KUM55899.1 - 4.3e-07 29.8 0.0 7.5e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KUM55899.1 - 8.4e-07 28.5 0.0 1.5e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM55899.1 - 0.044 13.6 0.1 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ArfGap PF01412.13 KUM55901.1 - 3.5e-35 120.3 0.1 3.5e-35 120.3 0.1 3.1 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf PH PF00169.24 KUM55901.1 - 1.9e-12 47.2 1.3 3e-12 46.6 0.1 1.9 2 0 0 2 2 2 1 PH domain Fungal_trans PF04082.13 KUM55902.1 - 7.7e-22 77.4 0.4 3.3e-21 75.3 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM55902.1 - 8.6e-10 38.3 11.3 8.6e-10 38.3 7.8 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAD PF02109.11 KUM55903.1 - 6.5e-42 142.1 0.3 5.8e-41 139.0 0.2 1.9 1 1 0 1 1 1 1 DAD family HA2 PF04408.18 KUM55904.1 - 1.3e-23 82.9 0.0 4.3e-23 81.2 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KUM55904.1 - 5.1e-22 77.8 0.0 3.7e-21 75.0 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KUM55904.1 - 3.9e-14 52.2 0.0 1.3e-13 50.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KUM55904.1 - 1.5e-09 37.5 0.3 1.1e-07 31.4 0.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KUM55904.1 - 8.9e-05 22.6 0.1 0.00028 21.0 0.1 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 KUM55904.1 - 0.00059 19.7 0.0 0.29 10.9 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 KUM55904.1 - 0.00079 18.4 0.1 0.0022 16.9 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_14 PF13173.1 KUM55904.1 - 0.0019 18.0 0.1 0.015 15.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 KUM55904.1 - 0.0043 16.5 0.4 0.017 14.5 0.2 2.0 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 KUM55904.1 - 0.0074 16.0 0.1 0.014 15.1 0.1 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain NB-ARC PF00931.17 KUM55904.1 - 0.011 14.5 0.1 0.019 13.8 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.4 KUM55904.1 - 0.012 14.5 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 KUM55904.1 - 0.016 14.8 1.0 0.3 10.7 0.0 2.7 3 0 0 3 3 3 0 NACHT domain KaiC PF06745.8 KUM55904.1 - 0.017 14.2 0.0 0.031 13.4 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.1 KUM55904.1 - 0.06 12.9 0.0 0.06 12.9 0.0 2.1 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 KUM55904.1 - 0.067 13.4 0.0 0.23 11.7 0.0 1.9 2 0 0 2 2 1 0 ABC transporter AAA_23 PF13476.1 KUM55904.1 - 0.069 13.4 0.0 0.43 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KUM55904.1 - 0.07 12.8 0.6 0.13 11.9 0.0 1.7 2 0 0 2 2 1 0 Archaeal ATPase Miro PF08477.8 KUM55904.1 - 0.14 12.6 0.0 0.42 11.1 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein CBFD_NFYB_HMF PF00808.18 KUM55905.1 - 1e-29 102.3 0.9 1.3e-29 101.9 0.6 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KUM55905.1 - 4e-07 30.0 0.1 5.8e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 KUM55905.1 - 0.00032 20.4 0.0 0.00047 19.9 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 KUM55905.1 - 0.00065 19.3 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 KUM55905.1 - 0.017 15.3 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A UDPG_MGDP_dh_N PF03721.9 KUM55908.1 - 2.9e-49 166.9 0.0 2.3e-31 108.6 0.1 2.4 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 KUM55908.1 - 2.5e-30 104.5 0.1 1e-29 102.6 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 KUM55908.1 - 6.9e-22 77.6 0.0 9.8e-17 61.0 0.0 3.4 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Saccharop_dh PF03435.13 KUM55908.1 - 0.0042 16.1 0.0 0.006 15.6 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase 2OG-FeII_Oxy_3 PF13640.1 KUM55910.1 - 1.3e-05 25.6 0.0 4.6e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KUM55910.1 - 0.00055 20.1 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily IKKbetaNEMObind PF12179.3 KUM55910.1 - 0.078 12.8 0.4 0.078 12.8 0.3 2.6 3 0 0 3 3 3 0 I-kappa-kinase-beta NEMO binding domain CDC45 PF02724.9 KUM55910.1 - 0.11 10.5 2.1 0.15 10.0 1.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1235 PF06822.7 KUM55910.1 - 0.22 10.4 0.0 0.34 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1235) Pox_RNA_Pol_19 PF05320.7 KUM55910.1 - 0.65 9.7 5.3 1.1 9.0 3.7 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Daxx PF03344.10 KUM55910.1 - 7.7 4.8 9.9 11 4.3 6.8 1.1 1 0 0 1 1 1 0 Daxx Family Paf1 PF03985.8 KUM55910.1 - 9.5 4.8 10.1 16 4.1 7.0 1.2 1 0 0 1 1 1 0 Paf1 PNP_UDP_1 PF01048.15 KUM55911.1 - 0.00014 20.8 0.5 0.00066 18.7 0.3 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 KUM55912.1 - 1.1e-13 51.1 0.2 2.6e-13 49.9 0.1 1.6 1 0 0 1 1 1 1 NACHT domain Rcd1 PF04078.8 KUM55912.1 - 0.013 14.3 0.0 0.029 13.2 0.0 1.5 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like OTT_1508_deam PF14441.1 KUM55913.1 - 1.6e-11 44.1 0.1 3.1e-11 43.2 0.1 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase DYW_deaminase PF14432.1 KUM55913.1 - 0.029 14.3 0.3 0.091 12.7 0.0 1.9 2 0 0 2 2 2 0 DYW family of nucleic acid deaminases VanZ PF04892.7 KUM55914.1 - 1.1e-12 48.0 1.7 1.6e-12 47.5 1.2 1.3 1 0 0 1 1 1 1 VanZ like family DUF4401 PF14351.1 KUM55914.1 - 0.002 17.2 0.2 0.0025 16.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) Antimicrobial20 PF08256.6 KUM55914.1 - 0.18 12.1 0.5 0.38 11.1 0.4 1.6 1 0 0 1 1 1 0 Aurein-like antibiotic peptide DUF4383 PF14325.1 KUM55914.1 - 0.2 11.6 1.9 0.68 9.9 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4383) Bromodomain PF00439.20 KUM55915.1 - 1.8e-17 63.0 0.0 5.5e-17 61.4 0.0 1.8 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 KUM55915.1 - 1.7e-09 37.2 0.0 6.1e-09 35.4 0.0 2.0 1 0 0 1 1 1 1 Bromodomain associated Y_phosphatase PF00102.22 KUM55916.1 - 1.3e-53 181.7 0.0 1.7e-53 181.4 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KUM55916.1 - 0.00075 19.7 0.0 0.0027 17.9 0.0 2.0 1 1 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KUM55916.1 - 0.0012 18.8 0.1 0.0044 17.0 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate DSPc PF00782.15 KUM55916.1 - 0.027 14.0 1.4 0.11 12.0 1.0 2.0 1 1 1 2 2 2 0 Dual specificity phosphatase, catalytic domain tRNA-synt_2b PF00587.20 KUM55917.1 - 8.6e-16 57.9 0.0 1.2e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) BTB PF00651.26 KUM55918.1 - 0.0021 18.0 0.0 0.0087 16.0 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain ABC_membrane PF00664.18 KUM55919.1 - 8.3e-69 232.0 33.3 2e-42 145.5 9.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KUM55919.1 - 2.6e-63 212.4 0.0 3.9e-33 114.6 0.0 3.1 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KUM55919.1 - 1.8e-15 56.8 1.9 9.6e-05 21.7 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KUM55919.1 - 7.9e-14 52.2 0.4 0.0058 16.6 0.0 4.3 3 1 0 3 3 3 3 AAA domain AAA_16 PF13191.1 KUM55919.1 - 7.1e-10 39.1 1.1 0.00024 21.1 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 KUM55919.1 - 1.9e-08 35.1 0.0 0.0039 17.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KUM55919.1 - 2e-08 33.5 0.0 0.0011 18.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KUM55919.1 - 2.1e-08 34.3 2.7 0.024 14.7 0.0 4.2 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KUM55919.1 - 2.4e-08 33.3 1.0 7.7e-05 22.1 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.24 KUM55919.1 - 3.3e-06 27.3 1.1 1.2 9.3 0.0 4.5 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 KUM55919.1 - 9e-06 26.1 0.5 0.2 11.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain MobB PF03205.9 KUM55919.1 - 2.1e-05 24.2 0.1 0.32 10.7 0.0 3.6 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KUM55919.1 - 3e-05 23.9 0.0 0.2 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KUM55919.1 - 4.2e-05 23.8 0.0 0.29 11.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KUM55919.1 - 4.9e-05 22.8 0.1 0.3 10.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KUM55919.1 - 8.6e-05 22.2 0.0 0.39 10.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 KUM55919.1 - 0.00015 21.6 2.5 0.34 10.8 0.1 4.0 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 KUM55919.1 - 0.00029 20.4 1.1 2.3 7.7 0.0 3.9 5 0 0 5 5 4 2 AAA domain AAA_28 PF13521.1 KUM55919.1 - 0.00038 20.4 0.1 0.22 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KUM55919.1 - 0.00047 19.8 0.0 0.43 10.3 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain SRP54 PF00448.17 KUM55919.1 - 0.0021 17.5 0.2 2.8 7.3 0.0 2.8 3 0 0 3 3 2 2 SRP54-type protein, GTPase domain Rad17 PF03215.10 KUM55919.1 - 0.0027 16.4 0.0 0.31 9.6 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein ATP-synt_ab PF00006.20 KUM55919.1 - 0.0041 16.6 0.3 1.8 7.9 0.0 3.1 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.2 KUM55919.1 - 0.0087 15.5 0.5 0.71 9.2 0.0 3.0 3 0 0 3 3 3 1 AAA-like domain AAA_14 PF13173.1 KUM55919.1 - 0.011 15.6 0.1 4.6 7.1 0.0 3.1 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 KUM55919.1 - 0.012 15.7 0.0 5.2 7.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_15 PF13175.1 KUM55919.1 - 0.014 14.4 0.1 0.17 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain PRK PF00485.13 KUM55919.1 - 0.016 14.7 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.18 KUM55919.1 - 0.02 14.8 0.2 8.7 6.3 0.1 3.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase IstB_IS21 PF01695.12 KUM55919.1 - 0.024 14.0 0.1 21 4.4 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein ATP_bind_1 PF03029.12 KUM55919.1 - 0.024 14.1 0.0 1.9 7.9 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.17 KUM55919.1 - 0.034 13.0 0.1 2 7.1 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Mg_chelatase PF01078.16 KUM55919.1 - 0.045 12.9 0.0 1.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI APS_kinase PF01583.15 KUM55919.1 - 0.07 12.7 0.0 5.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_24 PF13479.1 KUM55919.1 - 0.07 12.7 0.0 6.4 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KUM55919.1 - 0.072 12.7 0.1 12 5.5 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 KUM55919.1 - 0.084 11.9 0.0 11 5.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin ABC_ATPase PF09818.4 KUM55919.1 - 0.14 10.6 1.4 0.57 8.7 0.0 2.5 3 0 0 3 3 3 0 Predicted ATPase of the ABC class MBOAT PF03062.14 KUM55922.1 - 4.3e-45 154.2 22.6 9.7e-45 153.0 15.7 1.6 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 KUM55922.1 - 0.0041 17.1 2.2 0.012 15.6 1.5 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family ESSS PF10183.4 KUM55922.1 - 0.098 13.0 4.5 0.11 12.8 0.0 2.9 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) PCI PF01399.22 KUM55923.1 - 1.6e-06 28.4 0.0 2.5e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 PCI domain DUF1192 PF06698.6 KUM55923.1 - 0.34 10.7 3.7 0.44 10.3 1.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) DUF4349 PF14257.1 KUM55924.1 - 0.11 11.6 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Herpes_UL49_5 PF05702.6 KUM55925.1 - 0.66 9.8 3.8 0.91 9.4 0.1 2.0 1 1 1 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein UPF0197 PF05251.7 KUM55925.1 - 2.4 8.5 7.2 24 5.3 5.0 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0197) RGS PF00615.14 KUM55926.1 - 8.3e-12 45.2 0.0 7.4e-09 35.7 0.0 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain Bromodomain PF00439.20 KUM55927.1 - 4.8e-25 87.2 0.5 1e-24 86.2 0.4 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 KUM55927.1 - 8.8e-10 38.6 0.1 1.6e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KUM55927.1 - 3.1e-09 36.7 0.0 5.7e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Rad1 PF02144.11 KUM55928.1 - 1.1e-94 316.2 0.0 1.3e-94 316.0 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 DUF1751 PF08551.5 KUM55929.1 - 3.7e-28 97.7 2.5 8e-28 96.6 1.7 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 KUM55929.1 - 0.00013 21.9 5.9 0.00028 20.9 4.1 1.5 1 0 0 1 1 1 1 Rhomboid family ADH_zinc_N PF00107.21 KUM55930.1 - 1.1e-10 41.1 0.0 2.4e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM55930.1 - 1e-09 38.1 0.5 3.5e-08 33.1 0.1 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.11 KUM55931.1 - 7e-41 140.0 45.2 7e-41 140.0 31.3 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM55931.1 - 4e-16 58.3 27.1 5.5e-16 57.8 18.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KUM55931.1 - 5.1e-12 45.1 15.7 5.1e-12 45.1 10.9 3.3 1 1 0 3 3 3 2 Sugar (and other) transporter DUF2530 PF10745.4 KUM55931.1 - 2.9 7.9 10.7 12 5.9 1.2 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2530) ATG22 PF11700.3 KUM55931.1 - 4.6 5.6 34.1 0.016 13.7 7.7 2.7 3 1 0 3 3 3 0 Vacuole effluxer Atg22 like Zn_clus PF00172.13 KUM55932.1 - 1.1e-06 28.4 6.8 1.9e-06 27.6 4.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.21 KUM55933.1 - 6.1e-67 225.7 0.0 7.2e-67 225.5 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.18 KUM55933.1 - 5.5e-06 25.5 0.0 7.9e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 KUM55933.1 - 0.097 12.3 0.1 0.24 11.1 0.1 1.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III p450 PF00067.17 KUM55934.1 - 5.7e-51 173.4 0.0 6.6e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SRF-TF PF00319.13 KUM55939.1 - 1.1e-06 27.7 0.1 2.1e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) OrfB_Zn_ribbon PF07282.6 KUM55941.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF3435 PF11917.3 KUM55942.1 - 3.3e-161 536.6 0.0 4.9e-161 536.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) TRCF PF03461.10 KUM55942.1 - 0.0049 16.7 0.7 0.013 15.4 0.5 1.7 1 0 0 1 1 1 1 TRCF domain GET2 PF08690.5 KUM55942.1 - 0.43 9.7 2.3 0.76 8.9 1.6 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 DUF4407 PF14362.1 KUM55942.1 - 0.47 9.3 3.3 0.88 8.4 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C2H2 PF00096.21 KUM55942.1 - 0.94 9.9 4.4 2.6 8.5 0.5 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type CHZ PF09649.5 KUM55943.1 - 2e-12 46.1 1.9 2e-12 46.1 1.3 2.4 2 0 0 2 2 2 1 Histone chaperone domain CHZ Daxx PF03344.10 KUM55943.1 - 2.7 6.3 20.6 3.4 6.0 14.3 1.1 1 0 0 1 1 1 0 Daxx Family Na_trans_assoc PF06512.8 KUM55943.1 - 7 6.5 16.8 8.2 6.3 11.6 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated DUF2012 PF09430.5 KUM55945.1 - 1.6e-31 108.7 0.0 2e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) DUF2665 PF11654.3 KUM55946.1 - 2.7e-06 26.8 0.2 8.9e-06 25.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2665) HSP70 PF00012.15 KUM55947.1 - 4.5e-272 903.3 7.1 5.1e-272 903.1 4.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KUM55947.1 - 3.8e-18 65.1 0.1 1.8e-17 62.9 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 KUM55947.1 - 0.0007 19.4 1.6 0.48 10.2 0.1 3.1 2 2 0 2 2 2 2 Cell division protein FtsA FGGY_C PF02782.11 KUM55947.1 - 0.0014 18.3 0.0 0.0034 17.0 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.15 KUM55947.1 - 0.0085 15.4 0.1 0.82 8.9 0.0 2.4 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.13 KUM55947.1 - 0.0098 15.0 0.1 0.042 12.9 0.0 2.0 1 1 0 2 2 2 1 Hydantoinase/oxoprolinase StbA PF06406.6 KUM55947.1 - 0.043 12.7 0.0 0.085 11.7 0.0 1.4 1 0 0 1 1 1 0 StbA protein PMBR PF09373.5 KUM55947.1 - 0.061 13.2 0.1 0.36 10.8 0.0 2.3 2 0 0 2 2 2 0 Pseudomurein-binding repeat OPT PF03169.10 KUM55948.1 - 4.4e-138 461.4 47.8 5e-138 461.2 33.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.1 KUM55948.1 - 0.018 14.2 0.2 0.049 12.7 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF2207 PF09972.4 KUM55948.1 - 1.9 7.0 7.6 0.71 8.3 0.5 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) PBP1_TM PF14812.1 KUM55949.1 - 0.61 10.4 11.6 1.3 9.3 8.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_Ag35 PF03286.9 KUM55949.1 - 0.77 9.2 10.5 1.1 8.7 7.2 1.3 1 1 0 1 1 1 0 Pox virus Ag35 surface protein WW PF00397.21 KUM55950.1 - 2e-06 27.5 1.5 2e-06 27.5 1.0 2.0 2 0 0 2 2 2 1 WW domain DUF2076 PF09849.4 KUM55950.1 - 1.1e-05 25.5 22.3 1.1e-05 25.5 15.5 2.4 1 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) CYSTM PF12734.2 KUM55950.1 - 0.043 13.8 0.7 0.043 13.8 0.5 5.0 4 3 0 4 4 4 0 Cysteine-rich TM module stress tolerance DUF605 PF04652.11 KUM55950.1 - 2 7.7 8.9 2.6 7.3 6.2 1.2 1 0 0 1 1 1 0 Vta1 like Polysacc_lyase PF14099.1 KUM55951.1 - 2.9e-51 174.2 7.4 3.6e-51 173.9 5.1 1.1 1 0 0 1 1 1 1 Polysaccharide lyase Laminin_G_2 PF02210.19 KUM55951.1 - 0.0076 16.2 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Triabin PF03973.8 KUM55951.1 - 0.011 15.3 0.3 0.027 14.1 0.1 1.7 2 0 0 2 2 2 0 Triabin Glyco_hydro_32N PF00251.15 KUM55952.1 - 4.2e-95 318.6 5.2 5.6e-95 318.2 3.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 KUM55952.1 - 8.5e-20 70.9 0.3 7.8e-19 67.8 0.5 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal BNR_2 PF13088.1 KUM55952.1 - 0.003 16.8 0.5 0.018 14.3 0.3 2.1 1 1 0 1 1 1 1 BNR repeat-like domain Sugar_tr PF00083.19 KUM55954.1 - 7.6e-125 417.0 22.0 8.7e-125 416.8 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM55954.1 - 4.6e-22 78.2 27.3 4.6e-22 78.2 18.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily 7tm_1 PF00001.16 KUM55954.1 - 0.17 10.9 7.1 1 8.4 0.8 3.2 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) ABC_membrane PF00664.18 KUM55955.1 - 2.3e-81 273.2 41.2 1.9e-42 145.6 14.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KUM55955.1 - 2.3e-68 228.7 0.0 4.8e-33 114.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.1 KUM55955.1 - 2e-11 44.2 0.5 7e-06 26.1 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 KUM55955.1 - 4.1e-11 42.5 9.7 0.00022 20.5 0.4 5.1 4 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KUM55955.1 - 5.4e-11 42.9 3.6 0.00039 20.4 0.1 4.4 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KUM55955.1 - 5.8e-09 35.3 0.1 0.00013 21.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 KUM55955.1 - 1.6e-08 33.5 0.1 0.0069 15.0 0.1 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.1 KUM55955.1 - 1e-07 32.1 3.0 0.035 14.2 0.1 4.2 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 KUM55955.1 - 2.2e-07 30.1 0.0 0.023 13.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 KUM55955.1 - 7.8e-07 29.9 0.0 0.063 14.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KUM55955.1 - 4.7e-06 26.1 0.8 0.14 11.5 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_23 PF13476.1 KUM55955.1 - 1.8e-05 25.1 0.5 0.092 13.0 0.1 2.8 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 KUM55955.1 - 2e-05 24.3 0.1 1.1 9.0 0.0 3.4 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 KUM55955.1 - 5.2e-05 22.9 0.8 2.5 7.6 0.0 4.1 4 0 0 4 4 4 1 AAA domain ATP-synt_ab PF00006.20 KUM55955.1 - 0.00014 21.4 0.0 0.45 9.9 0.0 2.8 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.1 KUM55955.1 - 0.00022 21.1 0.0 0.5 10.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 KUM55955.1 - 0.00033 20.8 0.2 8.9 6.5 0.0 4.4 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 KUM55955.1 - 0.00056 19.7 1.6 0.72 9.8 0.1 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 KUM55955.1 - 0.0006 19.5 0.1 2.4 7.8 0.0 3.4 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KUM55955.1 - 0.00098 19.0 0.0 1.4 8.8 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_28 PF13521.1 KUM55955.1 - 0.0013 18.6 0.1 0.12 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KUM55955.1 - 0.0028 17.9 0.1 3.7 7.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KUM55955.1 - 0.006 16.3 0.0 1.5 8.6 0.0 3.0 2 0 0 2 2 2 1 Part of AAA domain Synapsin_N PF10581.4 KUM55955.1 - 0.013 15.2 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 0 Synapsin N-terminal NB-ARC PF00931.17 KUM55955.1 - 0.015 14.1 0.5 1 8.1 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain AAA_15 PF13175.1 KUM55955.1 - 0.016 14.2 0.0 0.12 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 KUM55955.1 - 0.018 14.1 0.0 2.3 7.2 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.16 KUM55955.1 - 0.024 13.8 0.0 0.41 9.7 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SRP54 PF00448.17 KUM55955.1 - 0.032 13.6 0.0 2 7.8 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 KUM55955.1 - 0.041 13.3 1.7 0.52 9.6 0.0 2.9 4 0 0 4 4 3 0 AAA-like domain MMR_HSR1 PF01926.18 KUM55955.1 - 0.058 13.3 0.0 20 5.1 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.7 KUM55955.1 - 0.058 13.0 0.1 13 5.3 0.0 2.7 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 KUM55955.1 - 0.062 13.4 0.0 11 6.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.1 KUM55955.1 - 0.071 12.6 0.2 5.7 6.4 0.0 2.8 3 0 0 3 3 2 0 AAA domain G-alpha PF00503.15 KUM55955.1 - 0.073 11.7 0.0 7.5 5.1 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit Miro PF08477.8 KUM55955.1 - 0.089 13.2 0.1 16 6.0 0.0 3.3 3 0 0 3 3 2 0 Miro-like protein PRK PF00485.13 KUM55955.1 - 0.14 11.7 0.2 5.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Seryl_tRNA_N PF02403.17 KUM55956.1 - 2.3e-10 40.4 3.6 1e-09 38.3 2.5 1.9 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain GOLGA2L5 PF15070.1 KUM55956.1 - 3.3e-05 22.6 2.0 4.4e-05 22.1 1.4 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 Atg14 PF10186.4 KUM55956.1 - 0.0026 16.7 0.4 0.003 16.5 0.3 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 KUM55956.1 - 0.0029 17.0 1.8 0.42 10.1 0.1 2.5 2 0 0 2 2 2 1 Septum formation initiator DUF2353 PF09789.4 KUM55956.1 - 0.0086 15.3 1.3 0.012 14.9 0.9 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) CENP-Q PF13094.1 KUM55956.1 - 0.0096 15.9 5.0 0.019 14.9 3.5 1.4 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 KUM55956.1 - 0.035 13.7 4.5 0.065 12.8 3.1 1.4 1 0 0 1 1 1 0 IncA protein WEMBL PF05701.6 KUM55956.1 - 0.078 11.4 4.6 0.1 11.0 3.2 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF724 PF05266.9 KUM55956.1 - 0.096 12.2 1.6 0.18 11.4 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4140 PF13600.1 KUM55956.1 - 0.12 12.8 2.6 4.1 7.8 0.1 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) bZIP_1 PF00170.16 KUM55956.1 - 0.18 11.7 9.4 0.4 10.6 0.1 2.9 3 0 0 3 3 3 0 bZIP transcription factor TMCO5 PF14992.1 KUM55956.1 - 0.19 10.8 4.2 0.29 10.2 2.9 1.2 1 0 0 1 1 1 0 TMCO5 family TBPIP PF07106.8 KUM55956.1 - 0.2 11.1 7.6 1.7 8.1 0.9 2.3 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CENP-F_leu_zip PF10473.4 KUM55956.1 - 0.22 11.3 8.4 0.39 10.5 0.4 2.3 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Striatin PF08232.7 KUM55956.1 - 0.31 11.3 7.1 0.26 11.5 3.6 1.8 2 0 0 2 2 2 0 Striatin family Mod_r PF07200.8 KUM55956.1 - 0.37 10.7 5.9 0.59 10.0 4.1 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein TMF_TATA_bd PF12325.3 KUM55956.1 - 0.51 10.0 6.0 7 6.4 3.4 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Mnd1 PF03962.10 KUM55956.1 - 0.65 9.6 8.6 1.7 8.2 6.0 1.6 1 1 0 1 1 1 0 Mnd1 family DUF342 PF03961.8 KUM55956.1 - 0.71 8.2 4.2 1.1 7.5 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Spectrin PF00435.16 KUM55956.1 - 1.1 9.5 6.9 0.66 10.2 1.2 2.2 1 1 1 2 2 2 0 Spectrin repeat DUF904 PF06005.7 KUM55956.1 - 1.2 9.5 7.3 3.1 8.1 0.4 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF904) TMF_DNA_bd PF12329.3 KUM55956.1 - 1.9 8.3 11.5 0.81 9.5 1.7 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 KUM55956.1 - 2.1 8.7 6.6 9.1 6.6 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF972) ADIP PF11559.3 KUM55956.1 - 2.5 7.9 10.2 4 7.3 1.3 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.6 KUM55956.1 - 4 6.0 7.9 17 3.9 5.6 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein Cytochrom_B561 PF03188.11 KUM55957.1 - 2.9e-15 56.3 4.6 2.9e-15 56.3 3.2 1.9 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 KUM55957.1 - 3.3 7.3 10.7 0.098 12.2 2.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF2427) DUF1129 PF06570.6 KUM55957.1 - 5.1 6.3 6.5 8.1 5.6 4.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Zn_clus PF00172.13 KUM55958.1 - 2.6e-06 27.2 17.0 3.4e-06 26.8 8.8 2.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KUM55958.1 - 7.5e-05 21.7 0.2 0.00011 21.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain WAC_Acf1_DNA_bd PF10537.4 KUM55959.1 - 7.6e-41 138.4 0.1 2.9e-40 136.5 0.1 2.1 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 KUM55959.1 - 1.8e-18 66.0 1.7 4.2e-18 64.8 1.2 1.6 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 KUM55959.1 - 7.6e-09 35.1 0.2 1.6e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 KUM55959.1 - 5.1e-05 23.0 0.2 0.00043 20.0 0.1 2.5 3 0 0 3 3 3 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM3 PF15614.1 KUM55959.1 - 0.00013 21.7 0.2 0.00037 20.2 0.1 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 DUF4094 PF13334.1 KUM55959.1 - 0.91 9.9 4.1 3.3 8.1 1.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) AKNA PF12443.3 KUM55959.1 - 1.4 8.9 12.5 0.073 13.1 2.8 3.0 3 0 0 3 3 3 0 AT-hook-containing transcription factor Alg6_Alg8 PF03155.10 KUM55961.1 - 7.5e-140 466.8 33.1 9.4e-140 466.5 22.9 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Lectin_leg-like PF03388.8 KUM55963.1 - 3.6e-27 94.9 0.0 5.4e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family BBP1_C PF15272.1 KUM55963.1 - 0.051 13.1 2.6 0.076 12.5 1.8 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal X_fast-SP_rel PF06669.6 KUM55963.1 - 0.079 12.9 0.1 0.34 10.8 0.0 2.2 2 0 0 2 2 2 0 Xylella fastidiosa surface protein related PHD PF00628.24 KUM55964.1 - 1.8e-17 62.7 25.2 7.2e-11 41.6 7.5 2.7 2 0 0 2 2 2 2 PHD-finger AIRC PF00731.15 KUM55964.1 - 0.0057 15.9 0.3 0.0098 15.1 0.2 1.3 1 0 0 1 1 1 1 AIR carboxylase zf-RanBP PF00641.13 KUM55964.1 - 0.014 14.5 0.2 0.014 14.5 0.2 2.9 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others C1_1 PF00130.17 KUM55964.1 - 0.014 15.0 15.2 0.14 11.8 2.9 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FMN_bind PF04205.9 KUM55964.1 - 0.056 13.6 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 FMN-binding domain Prok-RING_1 PF14446.1 KUM55964.1 - 1.4 8.7 25.8 0.15 11.8 3.2 2.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 HCO3_cotransp PF00955.16 KUM55965.1 - 3.7e-23 81.9 7.0 5.9e-22 78.0 2.5 2.1 1 1 1 2 2 2 2 HCO3- transporter family CorA PF01544.13 KUM55966.1 - 3e-46 157.7 0.0 3.9e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SET PF00856.23 KUM55967.1 - 5.2e-11 43.1 0.1 5.7e-10 39.7 0.0 2.2 2 0 0 2 2 2 1 SET domain Methyltransf_3 PF01596.12 KUM55968.1 - 1.6e-17 63.2 0.0 2e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 KUM55968.1 - 2.5e-10 41.1 0.0 3.7e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KUM55968.1 - 0.00011 22.2 0.0 0.00028 20.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM55968.1 - 0.00014 22.4 0.0 0.00021 21.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 KUM55968.1 - 0.0012 18.2 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 Cephalosporin hydroxylase FAD_binding_3 PF01494.14 KUM55969.1 - 1.6e-86 290.5 0.0 6.4e-86 288.6 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KUM55969.1 - 2.7e-37 128.0 0.0 5.9e-37 126.8 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 KUM55969.1 - 2e-06 26.9 0.5 5.5e-06 25.5 0.3 1.5 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KUM55969.1 - 2.8e-06 26.4 0.4 4.2e-06 25.8 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KUM55969.1 - 5e-06 25.2 0.1 7.8e-06 24.6 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 KUM55969.1 - 6.7e-06 25.4 1.0 1.5e-05 24.3 0.7 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KUM55969.1 - 2.2e-05 24.4 0.2 7.7e-05 22.6 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KUM55969.1 - 4e-05 22.8 0.1 7.8e-05 21.8 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 KUM55969.1 - 0.00022 21.2 0.1 0.0005 20.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KUM55969.1 - 0.00028 19.8 0.2 0.00046 19.1 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KUM55969.1 - 0.0019 18.2 0.9 0.0056 16.7 0.5 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KUM55969.1 - 0.0044 15.9 0.2 0.0076 15.2 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein ThiF PF00899.16 KUM55969.1 - 0.0093 15.7 0.3 0.083 12.7 0.2 2.3 2 0 0 2 2 2 1 ThiF family Pyr_redox PF00070.22 KUM55969.1 - 0.013 15.8 0.3 0.066 13.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KUM55969.1 - 0.069 11.7 0.1 0.1 11.2 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase 3HCDH_N PF02737.13 KUM55969.1 - 0.073 12.7 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Arrestin_N PF00339.24 KUM55970.1 - 0.03 14.1 0.1 0.035 13.9 0.0 1.1 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain DUF3365 PF11845.3 KUM55970.1 - 0.049 13.4 0.1 0.054 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) Zip PF02535.17 KUM55971.1 - 8.8e-39 133.3 10.4 1.4e-36 126.1 7.2 2.8 1 1 0 1 1 1 1 ZIP Zinc transporter DUF3649 PF12365.3 KUM55971.1 - 4 7.0 9.2 1.8 8.1 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3649) Zn_clus PF00172.13 KUM55972.1 - 4e-07 29.8 13.5 7.5e-07 28.9 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KUM55972.1 - 5.9e-05 21.8 0.7 0.0012 17.4 0.2 2.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain RTA1 PF04479.8 KUM55973.1 - 1.4e-42 145.6 5.2 2.2e-42 145.0 3.6 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF1554 PF07588.6 KUM55974.1 - 0.11 11.9 0.0 0.12 11.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1554) MFS_1 PF07690.11 KUM55975.1 - 1.5e-35 122.5 24.2 1.5e-35 122.5 16.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM55975.1 - 8.1e-10 37.8 11.5 8.1e-10 37.8 8.0 3.2 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KUM55975.1 - 1.2e-05 23.6 3.7 2e-05 23.0 2.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pmp3 PF01679.12 KUM55975.1 - 0.033 13.8 0.1 0.033 13.8 0.0 3.8 4 0 0 4 4 4 0 Proteolipid membrane potential modulator DUF2852 PF11014.3 KUM55975.1 - 0.15 12.0 0.1 3.1 7.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) Lyase_aromatic PF00221.14 KUM55976.1 - 5.1e-155 516.5 9.2 6.4e-155 516.1 6.4 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Bud13 PF09736.4 KUM55977.1 - 2.1e-46 157.7 7.2 2.1e-46 157.7 5.0 2.9 2 1 1 3 3 3 1 Pre-mRNA-splicing factor of RES complex DUF4551 PF15087.1 KUM55977.1 - 0.09 11.1 2.5 0.13 10.6 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF4613 PF15390.1 KUM55977.1 - 0.48 8.5 2.1 0.63 8.1 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Asp-B-Hydro_N PF05279.6 KUM55977.1 - 5 6.9 13.7 8.3 6.1 9.5 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Brr6_like_C_C PF10104.4 KUM55978.1 - 1.2e-41 141.3 0.4 1.7e-41 140.9 0.3 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DNA_binding_1 PF01035.15 KUM55979.1 - 1.8e-21 75.6 0.2 2.5e-21 75.2 0.1 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Pkinase PF00069.20 KUM55980.1 - 1.1e-41 142.6 0.6 2.4e-24 85.8 0.2 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KUM55980.1 - 3.8e-15 55.6 0.5 9.5e-11 41.2 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Metallophos PF00149.23 KUM55981.1 - 9.1e-06 25.1 5.0 0.00043 19.7 0.5 2.6 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KUM55981.1 - 0.00011 22.1 0.0 0.00023 21.0 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FMN_dh PF01070.13 KUM55982.1 - 1.4e-121 405.6 0.0 1.8e-121 405.3 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KUM55982.1 - 3.5e-24 84.3 0.0 8.3e-24 83.1 0.0 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KUM55982.1 - 8.4e-07 28.2 0.1 1.3e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 KUM55982.1 - 0.0002 20.6 0.1 0.00032 19.9 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KUM55982.1 - 0.00092 18.1 0.1 0.003 16.5 0.0 1.8 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 KUM55982.1 - 0.043 13.0 1.1 1.2 8.3 0.0 2.4 2 1 0 3 3 3 0 Histidine biosynthesis protein ThiG PF05690.9 KUM55982.1 - 0.072 12.1 0.0 7 5.6 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DUF561 PF04481.7 KUM55982.1 - 0.078 11.9 0.1 1.9 7.3 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF561) TPR_10 PF13374.1 KUM55983.1 - 1.4e-183 590.5 35.5 5.2e-13 48.4 0.0 15.7 15 0 0 15 15 15 15 Tetratricopeptide repeat TPR_12 PF13424.1 KUM55983.1 - 5.7e-159 516.4 31.0 1.7e-20 72.7 0.0 9.5 5 1 4 10 10 10 10 Tetratricopeptide repeat TPR_7 PF13176.1 KUM55983.1 - 3e-72 232.7 29.9 0.00013 21.4 0.0 16.1 16 0 0 16 16 15 15 Tetratricopeptide repeat TPR_1 PF00515.23 KUM55983.1 - 5.8e-63 206.1 25.2 0.0017 17.8 0.1 15.5 15 0 0 15 15 15 15 Tetratricopeptide repeat TPR_11 PF13414.1 KUM55983.1 - 3.3e-59 196.4 12.0 8e-08 31.8 0.2 8.6 7 1 0 8 8 8 7 TPR repeat TPR_2 PF07719.12 KUM55983.1 - 7.1e-35 116.1 36.4 0.094 12.6 0.1 15.5 15 0 0 15 15 15 13 Tetratricopeptide repeat TPR_16 PF13432.1 KUM55983.1 - 1e-34 118.4 32.3 5.9e-05 23.6 0.1 10.1 4 3 8 12 12 12 11 Tetratricopeptide repeat TPR_17 PF13431.1 KUM55983.1 - 1.8e-32 108.8 1.9 0.35 11.1 0.0 15.0 14 0 0 14 14 14 5 Tetratricopeptide repeat TPR_14 PF13428.1 KUM55983.1 - 9.2e-27 91.1 30.9 0.57 10.9 0.1 15.4 9 3 6 15 15 15 6 Tetratricopeptide repeat Rab5-bind PF09311.6 KUM55983.1 - 2.1e-22 79.9 14.6 0.038 13.8 0.1 10.1 1 1 9 11 11 11 9 Rabaptin-like protein TPR_4 PF07721.9 KUM55983.1 - 3.1e-21 73.5 0.8 5.8 7.6 0.0 14.6 15 0 0 15 15 14 1 Tetratricopeptide repeat Apc3 PF12895.2 KUM55983.1 - 1.8e-20 72.8 2.8 0.014 15.4 0.0 7.9 1 1 10 11 11 11 10 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KUM55983.1 - 7.8e-20 70.9 16.2 0.039 14.2 0.0 9.8 4 1 7 11 11 11 7 Tetratricopeptide repeat TPR_8 PF13181.1 KUM55983.1 - 4e-17 60.6 26.8 2.1 8.3 0.0 15.0 15 0 0 15 15 15 1 Tetratricopeptide repeat PPR PF01535.15 KUM55983.1 - 4.5e-12 45.0 21.4 0.57 10.2 0.0 12.4 14 0 0 14 14 14 3 PPR repeat DUF1925 PF09094.6 KUM55983.1 - 4.6e-11 42.5 26.6 12 5.9 0.0 14.5 8 4 7 15 15 15 0 Domain of unknown function (DUF1925) Tcf25 PF04910.9 KUM55983.1 - 3.2e-06 26.3 1.4 7.6 5.3 0.0 6.8 3 3 5 9 9 9 0 Transcriptional repressor TCF25 TPR_3 PF07720.7 KUM55983.1 - 8.9e-06 25.3 20.3 0.64 9.8 0.0 12.2 14 0 0 14 14 14 1 Tetratricopeptide repeat TPR_5 PF12688.2 KUM55983.1 - 9e-06 25.7 28.4 0.32 11.0 0.1 7.4 4 2 4 8 8 7 2 Tetratrico peptide repeat AAA_22 PF13401.1 KUM55983.1 - 0.00031 20.9 0.0 0.0028 17.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF4404 PF14357.1 KUM55983.1 - 0.0081 16.5 10.2 22 5.5 0.0 7.6 9 0 0 9 9 8 0 Domain of unknown function (DUF4404) FTCD PF02971.9 KUM55983.1 - 0.0093 15.6 0.5 45 3.6 0.0 5.9 5 3 3 8 8 7 0 Formiminotransferase domain NB-ARC PF00931.17 KUM55983.1 - 0.015 14.1 0.0 0.04 12.7 0.0 1.7 1 1 0 1 1 1 0 NB-ARC domain Opiods_neuropep PF01160.13 KUM55983.1 - 0.077 12.7 0.3 5.4 6.8 0.3 4.1 4 1 0 4 4 4 0 Vertebrate endogenous opioids neuropeptide DDE_1 PF03184.14 KUM55984.1 - 2.5e-48 164.0 0.0 3.7e-48 163.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 KUM55984.1 - 1.3e-06 28.0 0.0 3.5e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 KUM55984.1 - 0.082 12.4 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 helix-turn-helix, Psq domain DUF3292 PF11696.3 KUM55985.1 - 0.25 9.1 0.3 0.31 8.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) NPV_P10 PF05531.7 KUM55986.1 - 0.01 16.0 3.0 0.12 12.6 0.2 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.7 KUM55986.1 - 0.04 13.6 0.1 0.05 13.3 0.1 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1515 PF07439.6 KUM55986.1 - 0.076 12.8 0.2 0.23 11.2 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) Flagellin_N PF00669.15 KUM55986.1 - 0.087 12.6 0.3 0.12 12.1 0.2 1.2 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region DUF325 PF03804.8 KUM55986.1 - 0.098 12.3 0.1 2.5 7.8 0.0 2.2 1 1 1 2 2 2 0 Viral domain of unknown function APS_kinase PF01583.15 KUM55987.1 - 0.16 11.5 0.4 0.24 11.0 0.3 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase NACHT PF05729.7 KUM55988.1 - 0.051 13.2 0.3 0.12 12.0 0.2 1.6 1 0 0 1 1 1 0 NACHT domain KAP_NTPase PF07693.9 KUM55988.1 - 0.23 10.3 1.2 0.38 9.7 0.8 1.2 1 0 0 1 1 1 0 KAP family P-loop domain KH_2 PF07650.12 KUM55989.1 - 5.1e-07 29.1 0.2 0.57 9.7 0.1 3.1 2 1 1 3 3 3 3 KH domain DUF3596 PF12167.3 KUM55989.1 - 0.22 11.1 0.7 4.4 6.9 0.0 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF3596) Cucumo_2B PF03263.8 KUM55989.1 - 0.28 11.4 5.9 7.7 6.8 0.2 2.8 2 1 1 3 3 3 0 Cucumovirus protein 2B Glyco_hydro_18 PF00704.23 KUM55990.1 - 2.7e-91 306.5 7.2 3.2e-91 306.3 5.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.8 KUM55990.1 - 0.0062 15.6 0.0 0.0098 15.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 AP_endonuc_2 PF01261.19 KUM55990.1 - 0.014 14.6 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Nitroreductase PF00881.19 KUM55990.1 - 0.076 12.8 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Nitroreductase family Radical_SAM PF04055.16 KUM55990.1 - 0.16 12.1 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Radical SAM superfamily MFS_1 PF07690.11 KUM55991.1 - 5.8e-46 156.8 37.2 5.8e-46 156.8 25.8 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily DAP10 PF07213.6 KUM55991.1 - 0.046 13.4 0.8 2.1 8.1 0.0 2.7 2 0 0 2 2 2 0 DAP10 membrane protein TPT PF03151.11 KUM55992.1 - 4.7e-22 78.2 10.9 4.7e-22 78.2 7.5 1.8 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KUM55992.1 - 0.0085 15.0 17.2 0.018 13.9 12.0 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KUM55992.1 - 0.0086 16.1 3.4 0.0086 16.1 2.4 2.9 2 1 1 3 3 3 2 EamA-like transporter family Sugar_tr PF00083.19 KUM55994.1 - 2.1e-96 323.2 33.2 2.4e-96 323.0 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM55994.1 - 3.1e-26 91.9 41.7 1.1e-19 70.3 12.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC2_membrane_5 PF13346.1 KUM55994.1 - 0.0028 16.9 8.4 0.0028 16.9 5.8 3.2 4 0 0 4 4 4 1 ABC-2 family transporter protein Ribosomal_L18ae PF01775.12 KUM55996.1 - 5.2e-59 197.5 0.3 6.4e-59 197.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain CLTH PF10607.4 KUM55997.1 - 3.1e-28 98.2 0.0 5.1e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 KUM55997.1 - 7.7e-18 63.9 0.5 2.6e-17 62.2 0.4 2.0 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 KUM55997.1 - 3.4e-05 23.1 0.0 5.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.1 KUM55997.1 - 0.00033 20.4 0.2 0.00058 19.6 0.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KUM55997.1 - 0.00044 19.9 0.2 0.00073 19.2 0.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KUM55997.1 - 0.0063 16.5 0.5 0.011 15.7 0.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KUM55997.1 - 0.0069 16.0 0.3 0.011 15.3 0.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KUM55997.1 - 0.0098 15.5 0.3 0.017 14.7 0.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Syntaxin PF00804.20 KUM55997.1 - 0.058 13.5 0.5 0.24 11.5 0.1 2.1 2 0 0 2 2 2 0 Syntaxin zf-C3HC4_4 PF15227.1 KUM55997.1 - 0.079 12.8 0.6 0.15 11.9 0.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING LURAP PF14854.1 KUM55997.1 - 0.12 12.0 1.6 7.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Leucine rich adaptor protein PCI PF01399.22 KUM55998.1 - 1.7e-10 41.1 0.0 3.2e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 PCI domain Peptidase_M76 PF09768.4 KUM55998.1 - 0.16 11.4 0.0 0.45 9.9 0.0 1.7 2 0 0 2 2 2 0 Peptidase M76 family BTB PF00651.26 KUM55999.1 - 0.00034 20.5 0.0 0.0014 18.6 0.0 1.9 3 0 0 3 3 3 1 BTB/POZ domain NAD_binding_1 PF00175.16 KUM56000.1 - 2.3e-31 108.5 0.0 3.5e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KUM56000.1 - 4.2e-21 74.9 0.0 1.1e-20 73.6 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KUM56000.1 - 1.1e-08 35.1 0.0 4.4e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Golgin_A5 PF09787.4 KUM56001.1 - 0.014 13.9 0.0 0.024 13.1 0.0 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF2457 PF10446.4 KUM56002.1 - 0.041 12.6 5.4 0.045 12.4 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Med19 PF10278.4 KUM56002.1 - 2.8 7.6 11.0 0.62 9.7 2.4 2.1 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Peptidase_M20 PF01546.23 KUM56004.1 - 3.4e-22 78.8 0.3 4.5e-22 78.4 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KUM56004.1 - 4.6e-06 26.3 0.0 9.7e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KUM56004.1 - 0.0014 18.4 0.0 0.037 13.7 0.0 2.2 2 0 0 2 2 2 1 Peptidase family M28 CRISPR_Cse2 PF09485.5 KUM56005.1 - 0.017 15.1 0.0 0.023 14.7 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Herpes_BLLF1 PF05109.8 KUM56005.1 - 0.48 8.3 13.6 0.59 8.0 9.4 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) adh_short_C2 PF13561.1 KUM56006.1 - 7.2e-24 84.8 0.0 1e-23 84.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KUM56006.1 - 1.3e-20 74.0 0.6 1.8e-20 73.5 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM56006.1 - 1.2e-11 44.5 0.2 2e-11 43.8 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF2623 PF11115.3 KUM56009.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2623) Frag1 PF10277.4 KUM56012.1 - 4.7e-31 107.9 17.4 5.4e-31 107.7 12.1 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family SLAC1 PF03595.12 KUM56012.1 - 0.074 11.6 19.6 0.19 10.3 13.6 1.6 1 1 0 1 1 1 0 Voltage-dependent anion channel 7TMR-DISM_7TM PF07695.6 KUM56012.1 - 3.5 7.2 19.3 0.13 11.9 9.4 1.5 2 0 0 2 2 2 0 7TM diverse intracellular signalling Glyco_hydro_18 PF00704.23 KUM56013.1 - 5.3e-73 246.4 4.8 1e-72 245.4 3.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 KUM56014.1 - 0.00011 21.9 0.0 3.5 7.5 0.0 3.6 3 0 0 3 3 3 3 LysM domain Interfer-bind PF09294.5 KUM56014.1 - 0.026 14.5 1.0 0.16 11.9 0.0 2.3 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III adh_short PF00106.20 KUM56015.1 - 8.4e-18 64.8 1.6 1.6e-13 50.8 0.1 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KUM56015.1 - 2.8e-14 53.4 0.2 2.3e-13 50.5 0.2 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM56015.1 - 1.6e-06 27.9 0.5 4.6e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 KUM56015.1 - 0.0035 17.4 0.1 0.0058 16.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KUM56015.1 - 0.011 15.7 0.1 0.077 12.9 0.0 2.0 2 0 0 2 2 2 0 NADH(P)-binding NAD_binding_2 PF03446.10 KUM56015.1 - 0.041 13.7 0.1 0.079 12.8 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_tran_WecB PF03808.8 KUM56015.1 - 0.11 11.8 0.1 2.4 7.5 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family NAD_Gly3P_dh_N PF01210.18 KUM56015.1 - 0.12 12.1 0.1 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Hemerythrin PF01814.18 KUM56016.1 - 9.8e-12 45.1 0.3 1.3e-11 44.7 0.2 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain NumbF PF06311.7 KUM56016.1 - 0.068 13.2 0.7 0.13 12.4 0.5 1.4 1 0 0 1 1 1 0 NUMB domain Methyltransf_2 PF00891.13 KUM56017.1 - 1.2e-34 119.5 0.0 1.1e-30 106.6 0.0 2.1 2 0 0 2 2 2 2 O-methyltransferase Methyltransf_18 PF12847.2 KUM56017.1 - 0.00055 20.4 0.0 0.0015 19.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 KUM56017.1 - 0.027 13.7 0.0 0.058 12.6 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_12 PF08242.7 KUM56017.1 - 0.034 14.6 0.0 0.15 12.5 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Cu-oxidase_2 PF07731.9 KUM56018.1 - 3.6e-23 81.5 1.7 2.6e-21 75.5 0.3 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 KUM56018.1 - 1.9e-19 70.1 0.0 5.7e-19 68.5 0.0 1.8 1 1 0 1 1 1 1 Multicopper oxidase Fasciclin PF02469.17 KUM56019.1 - 5.9e-35 120.0 0.0 2.3e-21 76.1 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain DPBB_1 PF03330.13 KUM56019.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel AMP-binding PF00501.23 KUM56020.1 - 3.1e-154 513.3 0.1 4.2e-78 262.5 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KUM56020.1 - 6.3e-50 169.7 0.0 2.9e-26 92.0 0.0 3.3 2 1 1 3 3 3 3 Condensation domain PP-binding PF00550.20 KUM56020.1 - 2.6e-13 50.0 1.6 7.7e-06 26.0 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KUM56020.1 - 6.9e-08 33.3 0.0 0.00077 20.3 0.0 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain adh_short PF00106.20 KUM56022.1 - 5.9e-15 55.5 0.9 1.2e-14 54.5 0.6 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM56022.1 - 1.1e-06 28.4 0.6 1.8e-06 27.7 0.4 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KUM56022.1 - 0.00096 18.8 0.4 0.0036 17.0 0.1 2.0 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase CNPase PF05881.7 KUM56022.1 - 0.06 12.7 0.0 0.094 12.1 0.0 1.2 1 0 0 1 1 1 0 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) MFS_1 PF07690.11 KUM56023.1 - 1e-35 123.1 50.2 4.5e-35 121.0 34.8 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM56023.1 - 6.9e-09 34.7 17.9 6.9e-09 34.7 12.4 3.3 2 1 1 3 3 3 1 Sugar (and other) transporter DUF1673 PF07895.6 KUM56023.1 - 0.84 9.1 5.9 0.14 11.7 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1673) BBE PF08031.7 KUM56025.1 - 2.6e-07 30.4 0.3 2.6e-07 30.4 0.2 1.9 2 0 0 2 2 2 1 Berberine and berberine like DUF2423 PF10338.4 KUM56026.1 - 1.1e-18 66.8 3.1 1.1e-18 66.8 2.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) RR_TM4-6 PF06459.7 KUM56026.1 - 0.33 10.8 5.1 0.36 10.6 3.6 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Phosphodiest PF01663.17 KUM56028.1 - 1.5e-16 60.6 1.3 5.2e-15 55.6 1.2 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KUM56028.1 - 1.2e-05 24.6 0.0 0.00057 19.1 0.0 2.2 2 0 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.13 KUM56028.1 - 0.0027 17.1 0.0 0.0055 16.1 0.0 1.5 1 1 0 1 1 1 1 Metalloenzyme superfamily DUF229 PF02995.12 KUM56028.1 - 0.084 11.2 0.0 0.11 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Ldh_1_C PF02866.13 KUM56029.1 - 2.5e-41 141.2 0.0 3.2e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 KUM56029.1 - 5.1e-16 58.7 0.0 7.9e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain TRAPP PF04051.11 KUM56030.1 - 1.2e-44 151.4 0.0 1.4e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PorB PF11565.3 KUM56030.1 - 0.14 12.3 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Alpha helical Porin B DUF979 PF06166.7 KUM56031.1 - 0.06 12.2 0.1 0.075 11.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF979) PINIT PF14324.1 KUM56032.1 - 9.3e-41 139.2 0.4 2e-40 138.2 0.3 1.5 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 KUM56032.1 - 1.5e-21 75.6 7.6 2.6e-21 74.8 5.3 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KUM56032.1 - 9e-07 28.3 2.9 2.5e-06 26.9 2.0 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 KUM56032.1 - 1.5e-05 24.3 0.0 4e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 SAP domain zf-Sec23_Sec24 PF04810.10 KUM56032.1 - 0.61 9.6 3.5 1.4 8.4 1.6 2.2 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger Glyco_hydro_18 PF00704.23 KUM56033.1 - 1.5e-48 165.9 9.7 3e-48 165.0 6.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 KUM56033.1 - 2.7e-11 43.1 1.1 1.9e-05 24.4 0.0 3.7 3 0 0 3 3 3 2 LysM domain Chitin_bind_1 PF00187.14 KUM56033.1 - 1.3e-06 28.2 5.2 1.3e-06 28.2 3.6 3.3 2 0 0 2 2 2 1 Chitin recognition protein Hemopexin PF00045.14 KUM56034.1 - 0.21 11.3 10.8 5.4 6.8 3.0 3.3 2 1 0 2 2 2 0 Hemopexin SLAC1 PF03595.12 KUM56037.1 - 3.4e-75 252.7 43.7 3.9e-75 252.5 30.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel ATP-grasp_2 PF08442.5 KUM56038.1 - 4.9e-77 257.8 0.5 9.1e-77 257.0 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 KUM56038.1 - 6.1e-25 87.6 0.3 1.1e-24 86.7 0.2 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 KUM56038.1 - 6.3e-08 32.0 0.1 1.9e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 KUM56038.1 - 0.0014 18.2 1.5 0.044 13.3 0.1 2.5 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Ribosomal_S11 PF00411.14 KUM56038.1 - 0.0025 17.9 0.2 1.2 9.3 0.0 2.6 2 0 0 2 2 2 2 Ribosomal protein S11 ATP-grasp_4 PF13535.1 KUM56038.1 - 0.032 13.9 0.0 0.069 12.8 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain Peripla_BP_2 PF01497.13 KUM56038.1 - 0.052 12.6 1.1 0.08 12.0 0.0 1.8 2 0 0 2 2 2 0 Periplasmic binding protein Succ_CoA_lig PF13607.1 KUM56038.1 - 0.068 12.7 0.2 8.2 6.0 0.0 2.4 1 1 1 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain adh_short PF00106.20 KUM56039.1 - 1.6e-22 80.1 0.0 2.4e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM56039.1 - 6.3e-15 55.5 0.0 8e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KUM56039.1 - 0.00034 19.8 0.0 0.0017 17.5 0.0 1.8 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KUM56039.1 - 0.013 15.5 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding F-box PF00646.28 KUM56040.1 - 2.3e-06 27.1 1.4 1.5e-05 24.4 0.5 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KUM56040.1 - 0.00056 19.5 0.3 0.0014 18.3 0.2 1.7 1 0 0 1 1 1 1 F-box-like HSF_DNA-bind PF00447.12 KUM56041.1 - 7.8e-36 122.3 0.1 1.2e-35 121.7 0.1 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding AAA_12 PF13087.1 KUM56042.1 - 1.4e-35 122.5 0.0 2.8e-35 121.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KUM56042.1 - 4.4e-20 72.2 0.2 4.4e-20 72.2 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KUM56042.1 - 4.2e-07 29.6 0.1 2.4e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain DUF2075 PF09848.4 KUM56042.1 - 1.7e-06 27.3 0.3 0.0053 15.7 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) zf-CCCH PF00642.19 KUM56042.1 - 5.2e-05 22.8 6.1 0.00012 21.6 4.2 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AAA_16 PF13191.1 KUM56042.1 - 0.0013 18.7 0.5 0.013 15.5 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.1 KUM56042.1 - 0.0053 16.3 0.2 0.097 12.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KUM56042.1 - 0.014 14.5 1.3 0.11 11.6 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ResIII PF04851.10 KUM56042.1 - 0.026 14.3 0.0 0.072 12.9 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.1 KUM56042.1 - 0.094 12.8 0.0 0.27 11.4 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF3425 PF11905.3 KUM56044.1 - 2.2e-39 134.4 4.0 4e-39 133.6 2.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) HHH_5 PF14520.1 KUM56044.1 - 0.13 12.4 0.0 0.67 10.1 0.0 2.1 3 0 0 3 3 3 0 Helix-hairpin-helix domain bZIP_1 PF00170.16 KUM56044.1 - 0.22 11.5 6.7 0.4 10.6 4.6 1.3 1 0 0 1 1 1 0 bZIP transcription factor ACOX PF01756.14 KUM56045.1 - 7.2e-40 136.3 0.0 2e-39 134.9 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 KUM56045.1 - 6.2e-28 97.6 1.1 1.3e-27 96.5 0.7 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 KUM56045.1 - 1.9e-12 46.4 1.7 3.3e-12 45.7 0.4 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 KUM56045.1 - 3.4e-05 23.9 0.3 0.08 13.0 0.0 2.5 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain polyprenyl_synt PF00348.12 KUM56046.1 - 6.2e-11 41.6 0.0 1.7e-10 40.2 0.0 1.7 1 1 0 1 1 1 1 Polyprenyl synthetase Glyco_hydro_43 PF04616.9 KUM56047.1 - 4.8e-69 232.5 4.6 5.9e-69 232.3 3.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 MFS_1 PF07690.11 KUM56048.1 - 2e-23 82.7 50.6 1.8e-16 59.8 17.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 KUM56049.1 - 6.5e-23 81.2 0.0 2.1e-22 79.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM56049.1 - 1.3e-07 30.9 0.0 6.9e-05 22.0 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 KUM56049.1 - 0.059 13.0 0.0 0.51 10.0 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family TMF_DNA_bd PF12329.3 KUM56052.1 - 2.6e-05 23.9 36.6 0.00069 19.3 6.9 3.2 2 1 1 3 3 3 2 TATA element modulatory factor 1 DNA binding HAP1_N PF04849.8 KUM56052.1 - 0.00065 18.7 15.1 0.00065 18.7 10.5 2.1 1 1 1 2 2 2 1 HAP1 N-terminal conserved region IncA PF04156.9 KUM56052.1 - 0.00088 18.9 29.2 0.11 12.0 3.4 2.1 1 1 1 2 2 2 2 IncA protein Cast PF10174.4 KUM56052.1 - 0.0013 16.9 20.2 0.0017 16.5 14.0 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone DUF869 PF05911.6 KUM56052.1 - 0.0025 16.1 20.0 0.0029 15.9 13.9 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) Filo_VP35 PF02097.10 KUM56052.1 - 0.024 13.8 6.8 0.028 13.6 4.7 1.2 1 0 0 1 1 1 0 Filoviridae VP35 Atg14 PF10186.4 KUM56052.1 - 0.03 13.2 26.7 0.064 12.1 3.9 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ADIP PF11559.3 KUM56052.1 - 0.037 13.9 29.0 0.19 11.6 5.0 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Med9 PF07544.8 KUM56052.1 - 0.075 12.7 15.0 0.41 10.4 1.5 4.0 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 EzrA PF06160.7 KUM56052.1 - 0.079 11.1 19.9 0.019 13.2 5.7 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA YgbB PF02542.11 KUM56052.1 - 0.093 12.5 3.4 0.16 11.8 2.4 1.4 1 0 0 1 1 1 0 YgbB family DUF4200 PF13863.1 KUM56052.1 - 0.099 12.5 27.9 0.04 13.8 10.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) AAA_27 PF13514.1 KUM56052.1 - 0.11 10.1 19.7 0.18 9.4 13.7 1.3 1 1 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 KUM56052.1 - 0.11 11.5 11.9 0.15 11.1 4.7 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 KUM56052.1 - 0.15 12.1 22.5 0.17 12.0 7.6 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.7 KUM56052.1 - 0.15 12.3 10.1 0.95 9.7 0.5 3.2 1 1 2 3 3 2 0 Nucleopolyhedrovirus P10 protein G-gamma PF00631.17 KUM56052.1 - 0.16 11.7 0.2 0.16 11.7 0.1 3.1 2 1 1 3 3 2 0 GGL domain RE_Alw26IDE PF09665.5 KUM56052.1 - 0.16 10.6 14.6 0.39 9.3 10.1 1.5 1 1 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) DUF4201 PF13870.1 KUM56052.1 - 0.21 11.0 26.2 0.42 10.0 3.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) Glutaredoxin2_C PF04399.8 KUM56052.1 - 0.25 10.9 8.4 1.9 8.0 0.6 2.6 1 1 2 3 3 3 0 Glutaredoxin 2, C terminal domain HTH_Tnp_Mu_1 PF02316.11 KUM56052.1 - 0.28 10.8 5.6 0.14 11.8 1.5 2.1 1 1 1 2 2 2 0 Mu DNA-binding domain zf-C4H2 PF10146.4 KUM56052.1 - 0.38 10.7 14.0 0.6 10.1 9.7 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein LPP PF04728.8 KUM56052.1 - 0.48 10.2 11.1 0.48 10.2 1.7 3.4 1 1 4 5 5 5 0 Lipoprotein leucine-zipper DUF4559 PF15112.1 KUM56052.1 - 0.61 9.1 12.0 0.84 8.7 8.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF1319 PF07028.6 KUM56052.1 - 0.89 9.7 19.0 0.073 13.2 6.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1319) CENP-H PF05837.7 KUM56052.1 - 1 9.5 29.7 0.26 11.4 6.8 3.2 1 1 2 3 3 3 0 Centromere protein H (CENP-H) Prefoldin_2 PF01920.15 KUM56052.1 - 1 9.1 27.6 0.56 9.9 10.3 3.1 1 1 2 3 3 3 0 Prefoldin subunit Rootletin PF15035.1 KUM56052.1 - 1.3 8.9 24.3 1.2 9.1 10.6 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion AAA_13 PF13166.1 KUM56052.1 - 1.3 7.3 24.0 2.4 6.4 16.6 1.4 1 1 0 1 1 1 0 AAA domain IFP_35_N PF07334.8 KUM56052.1 - 1.8 8.5 15.0 4.9 7.1 0.8 3.4 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Flu_NS2 PF00601.14 KUM56052.1 - 1.8 8.7 9.1 3 8.1 0.7 2.5 1 1 0 2 2 2 0 Influenza non-structural protein (NS2) COG5 PF10392.4 KUM56052.1 - 1.9 8.4 16.3 1.6 8.7 6.9 2.8 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DivIVA PF05103.8 KUM56052.1 - 2.3 8.2 28.7 2.5 8.1 8.1 2.2 1 1 1 2 2 2 0 DivIVA protein Sec2p PF06428.6 KUM56052.1 - 2.3 8.1 21.2 3 7.7 3.3 2.9 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p DUF2570 PF10828.3 KUM56052.1 - 2.5 7.7 22.3 0.16 11.5 4.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2570) V_ATPase_I PF01496.14 KUM56052.1 - 3.1 5.5 18.2 8.8 4.0 12.6 1.7 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.6 KUM56052.1 - 3.5 6.2 27.2 49 2.4 18.9 2.1 1 1 0 1 1 1 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.4 KUM56052.1 - 3.5 7.4 29.6 3.2e+02 1.1 20.8 2.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG2 PF06148.6 KUM56052.1 - 5 7.0 14.0 3 7.7 6.0 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4164 PF13747.1 KUM56052.1 - 6.4 6.9 15.3 0.22 11.6 4.6 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) CCDC155 PF14662.1 KUM56052.1 - 8.1 5.9 29.9 1.3 8.5 5.6 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 DUF2664 PF10867.3 KUM56052.1 - 8.5 7.0 15.1 0.81 10.3 1.0 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF2664) DUF3723 PF12520.3 KUM56053.1 - 8.6e-121 403.9 0.8 1.7e-66 224.7 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3723) Angiomotin_C PF12240.3 KUM56054.1 - 1.2 8.6 7.0 0.98 8.8 3.6 1.7 2 0 0 2 2 2 0 Angiomotin C terminal Dynamin_N PF00350.18 KUM56056.1 - 4e-17 62.5 0.1 1e-16 61.1 0.0 1.8 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 KUM56056.1 - 2.3e-07 29.8 0.0 5.5e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region GED PF02212.13 KUM56056.1 - 0.00013 21.7 0.2 0.0012 18.7 0.0 2.7 2 1 0 2 2 2 1 Dynamin GTPase effector domain DUF4413 PF14372.1 KUM56057.1 - 1.1e-06 28.5 0.0 1.9e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4413) COesterase PF00135.23 KUM56058.1 - 7.5e-13 48.0 0.0 8.3e-13 47.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family MFS_1 PF07690.11 KUM56059.1 - 7.7e-28 97.2 37.2 7.7e-28 97.2 25.8 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM56059.1 - 0.00033 19.3 5.3 0.00033 19.3 3.7 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter Alpha-amylase PF00128.19 KUM56060.1 - 7.8e-72 242.3 1.0 1.2e-71 241.7 0.7 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 KUM56060.1 - 8.7e-32 109.0 0.2 2.5e-31 107.6 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) CBM_20 PF00686.14 KUM56060.1 - 3.5e-30 103.4 0.2 8e-30 102.3 0.2 1.6 1 0 0 1 1 1 1 Starch binding domain SBBP PF06739.6 KUM56060.1 - 0.0097 15.6 1.2 0.18 11.6 0.1 3.3 2 0 0 2 2 2 1 Beta-propeller repeat Glyco_hydro_15 PF00723.16 KUM56061.1 - 4e-106 355.2 0.4 4.8e-106 354.9 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 KUM56061.1 - 1.7e-31 107.6 1.1 4.7e-31 106.2 0.8 1.8 1 0 0 1 1 1 1 Starch binding domain Fungal_trans PF04082.13 KUM56062.1 - 5.1e-08 32.1 0.0 7.7e-08 31.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 KUM56065.1 - 3.6e-19 69.0 0.0 6.8e-09 35.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Amino_oxidase PF01593.19 KUM56065.1 - 5.9e-06 25.6 0.0 0.0098 15.0 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 KUM56065.1 - 0.00011 21.2 0.1 0.0058 15.5 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.19 KUM56065.1 - 0.066 12.0 0.0 9.2 5.0 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF3112 PF11309.3 KUM56066.1 - 3.5e-45 153.6 12.6 7.1e-42 142.9 1.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) Tmemb_18A PF09771.4 KUM56066.1 - 5 7.1 6.5 3.6 7.5 0.7 2.8 2 1 1 3 3 3 0 Transmembrane protein 188 APH PF01636.18 KUM56069.1 - 5.3e-09 36.1 0.3 1.4e-08 34.7 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family CENP-B_dimeris PF09026.5 KUM56069.1 - 0.0014 18.8 4.8 0.0014 18.8 3.3 3.5 3 0 0 3 3 3 2 Centromere protein B dimerisation domain Ribosomal_S25 PF03297.10 KUM56070.1 - 3.4e-39 133.1 3.5 3.7e-39 132.9 2.5 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.2 KUM56070.1 - 0.013 15.1 0.1 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_DeoR PF08220.7 KUM56070.1 - 0.028 13.9 0.1 0.037 13.5 0.1 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Rrf2 PF02082.15 KUM56070.1 - 0.067 13.3 0.1 0.097 12.7 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator GntR PF00392.16 KUM56070.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Cyt-b5 PF00173.23 KUM56071.1 - 1.6e-11 43.8 0.0 2.1e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF473 PF04322.7 KUM56071.1 - 0.0089 15.6 0.1 0.014 15.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF473) NQR2_RnfD_RnfE PF03116.10 KUM56071.1 - 0.013 14.7 0.0 0.017 14.3 0.0 1.1 1 0 0 1 1 1 0 NQR2, RnfD, RnfE family EAF PF09816.4 KUM56073.1 - 1.4e-23 82.9 0.1 2.7e-23 81.9 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Cyclin_N PF00134.18 KUM56074.1 - 9.5e-16 57.5 1.3 3.1e-15 55.8 0.4 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KUM56074.1 - 1.3e-06 28.3 0.1 0.00014 21.7 0.0 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain Pex24p PF06398.6 KUM56074.1 - 0.002 16.9 0.1 0.024 13.4 0.0 2.1 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin TFIIB PF00382.14 KUM56074.1 - 0.73 9.6 4.9 0.97 9.2 0.5 2.6 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Dehydrin PF00257.14 KUM56075.1 - 0.6 10.4 8.6 0.074 13.3 1.5 2.4 2 1 0 2 2 2 0 Dehydrin Rrn6 PF10214.4 KUM56075.1 - 2.2 6.2 6.9 2.8 5.9 4.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor cNMP_binding PF00027.24 KUM56076.1 - 1.1e-41 140.5 0.0 3.8e-22 77.8 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Fork_head PF00250.13 KUM56077.1 - 3.8e-16 58.8 0.0 7.1e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 KUM56077.1 - 2e-06 27.7 0.0 4.3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain 2OG-FeII_Oxy_3 PF13640.1 KUM56078.1 - 8.2e-10 39.0 0.0 1.3e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KUM56078.1 - 3.4e-09 36.1 0.3 7.8e-09 35.0 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KUM56078.1 - 0.0061 16.8 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RPN7 PF10602.4 KUM56079.1 - 2.2e-54 183.4 0.1 3.3e-54 182.9 0.1 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KUM56079.1 - 9e-12 45.2 0.0 9.1e-11 42.0 0.0 2.4 2 0 0 2 2 2 1 PCI domain TPR_16 PF13432.1 KUM56079.1 - 0.0061 17.1 2.4 4.6 8.0 0.6 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KUM56079.1 - 0.094 12.6 0.8 3.5 7.7 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1010 PF06231.6 KUM56081.1 - 0.18 11.8 2.6 0.36 10.8 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1010) p450 PF00067.17 KUM56082.1 - 4e-64 216.8 0.0 4.9e-64 216.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 KUM56083.1 - 5.4e-21 74.9 0.0 9.3e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM56083.1 - 4.6e-08 33.4 0.0 8.5e-07 29.3 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM56083.1 - 1.3e-07 31.9 0.0 2.8e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM56083.1 - 1.4e-07 32.1 0.0 2.1e-06 28.2 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM56083.1 - 0.00016 22.0 0.0 0.00036 20.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM56083.1 - 0.00064 19.3 0.0 0.008 15.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KUM56083.1 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_16 PF10294.4 KUM56083.1 - 0.062 12.7 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 KUM56083.1 - 0.084 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.7 KUM56083.1 - 0.16 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) adh_short PF00106.20 KUM56084.1 - 9.1e-20 71.2 0.1 1.3e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM56084.1 - 5.4e-07 29.4 0.0 9.9e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KUM56084.1 - 1.5e-05 24.9 0.0 3.6e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KUM56084.1 - 0.013 14.6 0.0 0.029 13.5 0.0 1.6 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KUM56084.1 - 0.069 13.1 0.2 0.26 11.2 0.1 2.1 1 1 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KUM56084.1 - 0.09 12.5 0.1 0.39 10.5 0.1 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Isochorismatase PF00857.15 KUM56085.1 - 1.5e-43 148.7 0.1 1.7e-43 148.5 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family DUF87 PF01935.12 KUM56085.1 - 0.069 12.9 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 Glyco_hydro_3 PF00933.16 KUM56086.1 - 4.1e-79 265.6 0.0 5.9e-79 265.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KUM56086.1 - 3.6e-52 177.1 0.0 8.6e-52 175.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KUM56086.1 - 2.2e-20 72.3 0.0 4.6e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Cupin_2 PF07883.6 KUM56087.1 - 2.1e-20 71.9 0.7 3e-10 39.4 0.2 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KUM56087.1 - 1.8e-17 62.4 2.2 1.1e-13 50.3 0.3 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF861) Cupin_1 PF00190.17 KUM56087.1 - 2.6e-06 26.9 0.0 0.00037 19.9 0.0 2.4 2 1 0 2 2 2 1 Cupin AraC_binding PF02311.14 KUM56087.1 - 6.6e-06 25.8 0.3 0.029 14.0 0.0 2.2 2 0 0 2 2 2 2 AraC-like ligand binding domain CENP-C_C PF11699.3 KUM56087.1 - 4e-05 23.5 0.0 8e-05 22.5 0.0 1.5 2 0 0 2 2 2 1 Mif2/CENP-C like Cupin_6 PF12852.2 KUM56087.1 - 0.0039 16.8 0.0 0.64 9.6 0.0 2.2 1 1 1 2 2 2 2 Cupin MannoseP_isomer PF01050.13 KUM56087.1 - 0.045 13.3 0.0 0.29 10.7 0.0 1.9 2 0 0 2 2 2 0 Mannose-6-phosphate isomerase DUF2793 PF10983.3 KUM56087.1 - 0.083 12.7 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2793) DnaJ PF00226.26 KUM56088.1 - 1.1e-15 57.0 1.2 1.1e-15 57.0 0.8 2.1 2 0 0 2 2 2 1 DnaJ domain DUF2277 PF10041.4 KUM56088.1 - 0.16 11.9 1.2 0.37 10.7 0.0 2.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2277) PAPS_reduct PF01507.14 KUM56089.1 - 1e-24 87.3 0.0 5.8e-23 81.6 0.0 2.1 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family AA_permease PF00324.16 KUM56090.1 - 2e-126 422.1 38.0 2.2e-126 422.0 26.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KUM56090.1 - 2.5e-44 151.4 43.5 3.3e-44 151.1 30.1 1.2 1 0 0 1 1 1 1 Amino acid permease DEAD PF00270.24 KUM56091.1 - 1.9e-44 151.1 0.0 3.5e-44 150.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KUM56091.1 - 1.7e-25 88.3 0.1 3.7e-25 87.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KUM56091.1 - 1.9e-21 75.7 0.0 4.6e-21 74.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KUM56091.1 - 0.003 17.4 0.0 0.003 17.4 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KUM56091.1 - 0.06 13.0 0.0 0.65 9.7 0.0 2.5 3 0 0 3 3 3 0 Part of AAA domain RRM_1 PF00076.17 KUM56092.1 - 3.6e-21 74.5 0.0 8.8e-10 38.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM56092.1 - 1.2e-13 50.7 0.0 9.6e-07 28.6 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM56092.1 - 0.01 15.7 1.7 0.13 12.1 0.1 2.8 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UspB PF10625.4 KUM56093.1 - 0.14 11.9 0.1 0.23 11.2 0.1 1.3 1 0 0 1 1 1 0 Universal stress protein B (UspB) Ank_2 PF12796.2 KUM56094.1 - 3.3e-42 142.7 3.4 1.1e-18 67.3 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KUM56094.1 - 1.5e-26 90.7 3.8 1.7e-06 27.5 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 KUM56094.1 - 3.8e-25 87.3 10.4 1.5e-10 40.9 0.3 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM56094.1 - 2.2e-20 70.7 2.9 0.00014 21.7 0.0 4.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 KUM56094.1 - 7.4e-19 67.7 9.0 1.8e-07 31.5 0.1 3.8 1 1 3 4 4 4 3 Ankyrin repeats (many copies) bZIP_1 PF00170.16 KUM56094.1 - 0.011 15.6 8.5 0.022 14.6 5.9 1.4 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.10 KUM56094.1 - 0.28 11.0 9.6 0.59 10.0 6.6 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Cupin_1 PF00190.17 KUM56095.1 - 1.5e-26 92.5 0.0 1.7e-13 50.2 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 KUM56095.1 - 3.8e-23 80.7 0.7 7e-12 44.6 0.1 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KUM56095.1 - 4.5e-08 32.3 0.0 0.01 15.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 KUM56095.1 - 4.6e-07 29.6 0.0 2.9e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_6 PF12852.2 KUM56095.1 - 6.2e-05 22.6 0.1 0.014 15.0 0.0 2.3 2 0 0 2 2 2 2 Cupin MannoseP_isomer PF01050.13 KUM56095.1 - 0.0017 17.9 0.0 0.057 13.0 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase 3-HAO PF06052.7 KUM56095.1 - 0.0057 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase FdtA PF05523.6 KUM56095.1 - 0.023 14.1 0.0 0.41 10.1 0.0 2.2 2 0 0 2 2 2 0 WxcM-like, C-terminal DUF1971 PF09313.6 KUM56095.1 - 0.026 14.2 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) Cupin_4 PF08007.7 KUM56095.1 - 0.06 12.5 0.0 0.26 10.4 0.0 1.8 2 0 0 2 2 2 0 Cupin superfamily protein ARD PF03079.9 KUM56095.1 - 0.067 13.1 0.1 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 ARD/ARD' family DUF4557 PF15101.1 KUM56095.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Arginase PF00491.16 KUM56096.1 - 1.5e-27 96.6 0.0 1.8e-27 96.3 0.0 1.0 1 0 0 1 1 1 1 Arginase family Epimerase PF01370.16 KUM56099.1 - 8.4e-12 45.0 0.2 1.2e-09 37.9 0.1 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KUM56099.1 - 1e-07 32.2 0.1 1.9e-07 31.4 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 KUM56099.1 - 1e-07 31.4 0.1 1.7e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KUM56099.1 - 8.1e-07 29.2 0.1 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KUM56099.1 - 3.9e-05 22.5 0.0 0.00011 21.0 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KUM56099.1 - 8.5e-05 21.5 0.0 0.00037 19.4 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Saccharop_dh PF03435.13 KUM56099.1 - 0.0017 17.4 0.3 0.0036 16.3 0.1 1.6 1 1 1 2 2 2 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 KUM56099.1 - 0.0018 17.2 0.1 0.003 16.5 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DXP_reductoisom PF02670.11 KUM56099.1 - 0.003 18.0 0.0 0.0047 17.4 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase RmlD_sub_bind PF04321.12 KUM56099.1 - 0.015 14.1 0.2 0.052 12.4 0.2 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain GFO_IDH_MocA PF01408.17 KUM56099.1 - 0.036 14.5 0.1 0.086 13.3 0.1 1.6 2 0 0 2 2 1 0 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 KUM56099.1 - 0.058 13.3 0.1 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus LSM PF01423.17 KUM56101.1 - 6.1e-13 48.1 0.1 9.1e-13 47.5 0.1 1.3 1 0 0 1 1 1 1 LSM domain NUC173 PF08161.7 KUM56102.1 - 3e-77 258.4 0.0 2.2e-75 252.3 0.0 2.6 2 0 0 2 2 2 2 NUC173 domain HEAT PF02985.17 KUM56102.1 - 0.098 12.7 1.9 33 4.9 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat DUF2457 PF10446.4 KUM56102.1 - 0.66 8.6 11.5 1.2 7.7 7.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Menin PF05053.8 KUM56104.1 - 5.6 4.9 5.6 7.5 4.5 3.9 1.1 1 0 0 1 1 1 0 Menin AA_permease PF00324.16 KUM56105.1 - 3.8e-73 246.4 22.1 4.4e-73 246.2 15.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KUM56105.1 - 2e-20 72.7 21.3 2.2e-20 72.6 14.8 1.0 1 0 0 1 1 1 1 Amino acid permease TMEM213 PF15192.1 KUM56105.1 - 0.082 12.9 0.3 0.3 11.1 0.2 1.9 1 0 0 1 1 1 0 TMEM213 family AA_permease PF00324.16 KUM56106.1 - 8.7e-15 54.0 7.3 1e-14 53.7 5.1 1.0 1 0 0 1 1 1 1 Amino acid permease Fungal_trans PF04082.13 KUM56107.1 - 6.8e-20 71.0 0.5 1.4e-19 69.9 0.3 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_3 PF00202.16 KUM56108.1 - 2e-93 312.9 0.0 2.5e-93 312.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KUM56108.1 - 0.043 12.7 0.0 0.14 11.1 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class I and II F-box-like_2 PF13013.1 KUM56108.1 - 0.083 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 F-box-like domain DUF4407 PF14362.1 KUM56109.1 - 0.18 10.7 15.8 0.19 10.6 10.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.7 KUM56109.1 - 1.3 8.8 18.6 1.5 8.6 12.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Gastrin PF00918.12 KUM56109.1 - 1.7 9.5 7.5 1.9 9.2 5.2 1.2 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Guanylin PF02058.10 KUM56109.1 - 1.7 8.7 5.1 9.2 6.4 3.6 2.1 1 1 0 1 1 1 0 Guanylin precursor Peptidase_S49_N PF08496.5 KUM56109.1 - 2.2 8.0 14.9 2.8 7.7 10.3 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Cytochrome-c551 PF10643.4 KUM56109.1 - 2.7 7.2 5.9 2.8 7.1 4.1 1.1 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Tho2 PF11262.3 KUM56109.1 - 4.4 6.2 9.7 4.3 6.2 6.7 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Herpes_UL6 PF01763.11 KUM56109.1 - 7.1 4.6 9.7 7.6 4.5 6.7 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like Glyco_hydro_20 PF00728.17 KUM56110.1 - 3.9e-95 318.9 0.9 4.9e-95 318.6 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 KUM56110.1 - 5.6e-20 72.2 0.0 1e-19 71.4 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 KUM56110.1 - 1.4e-06 28.8 0.0 2.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DHDPS PF00701.17 KUM56111.1 - 4.6e-54 182.9 0.0 5.5e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Bac_rhodopsin PF01036.13 KUM56113.1 - 4.1e-30 104.7 14.7 5.1e-30 104.4 10.2 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein UPF0093 PF03653.8 KUM56113.1 - 0.015 15.2 2.8 0.019 14.9 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0093) DUF805 PF05656.9 KUM56113.1 - 0.038 13.8 0.1 0.038 13.8 0.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF805) tRNA-synt_1 PF00133.17 KUM56114.1 - 7.5e-160 532.8 0.0 9.6e-160 532.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KUM56114.1 - 9.3e-22 77.2 0.0 6.5e-12 44.8 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KUM56114.1 - 9.9e-19 67.6 0.3 1.7e-18 66.8 0.2 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.9 KUM56114.1 - 0.00049 19.6 2.4 0.001 18.6 1.6 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.1 KUM56114.1 - 0.003 16.8 0.0 0.0059 15.9 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 KUM56114.1 - 0.081 12.0 0.0 6.5 5.7 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain ABC_tran PF00005.22 KUM56116.1 - 3.8e-33 114.6 0.0 6.8e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KUM56116.1 - 7.3e-24 84.6 7.7 7.3e-24 84.6 5.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KUM56116.1 - 2.2e-07 30.3 0.1 0.0002 20.6 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KUM56116.1 - 4.2e-06 26.9 0.0 7.6e-05 22.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.4 KUM56116.1 - 8.2e-05 21.3 0.1 0.0017 16.9 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_29 PF13555.1 KUM56116.1 - 9e-05 21.9 0.3 0.00022 20.7 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 KUM56116.1 - 0.014 14.5 0.1 0.034 13.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 KUM56116.1 - 0.019 14.3 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KUM56116.1 - 0.021 14.7 0.3 0.067 13.1 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KUM56116.1 - 0.046 13.8 0.4 0.74 9.9 0.3 2.4 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 KUM56116.1 - 0.048 13.5 0.1 0.28 11.1 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_membrane PF00664.18 KUM56117.1 - 5.6e-26 91.5 4.7 6.9e-26 91.2 3.3 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region Aa_trans PF01490.13 KUM56118.1 - 1.6e-38 132.2 29.2 1.8e-38 132.0 20.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein E1-E2_ATPase PF00122.15 KUM56118.1 - 1.4 7.9 12.2 0.84 8.6 3.7 2.4 2 0 0 2 2 2 0 E1-E2 ATPase ABC_tran PF00005.22 KUM56119.1 - 3e-32 111.7 0.0 4.9e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KUM56119.1 - 1.5e-06 28.3 0.0 0.034 14.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KUM56119.1 - 7.1e-06 25.4 0.0 0.0014 17.9 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KUM56119.1 - 0.00013 22.1 0.1 0.001 19.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.4 KUM56119.1 - 0.00016 20.4 0.4 0.015 13.9 0.1 2.1 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 KUM56119.1 - 0.00028 20.9 0.7 0.00091 19.2 0.5 1.8 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 KUM56119.1 - 0.00047 19.3 0.0 0.00083 18.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KUM56119.1 - 0.00082 18.8 0.3 0.06 12.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KUM56119.1 - 0.0011 18.5 0.0 0.31 10.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KUM56119.1 - 0.0043 16.9 0.4 0.024 14.5 0.3 2.1 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KUM56119.1 - 0.0043 16.5 0.3 0.0099 15.3 0.0 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 KUM56119.1 - 0.0057 17.4 0.0 0.0099 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KUM56119.1 - 0.014 15.6 0.0 4.3 7.5 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KUM56119.1 - 0.056 13.3 0.4 0.1 12.5 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KUM56119.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.13 KUM56120.1 - 1.9e-33 115.4 1.6 2e-33 115.3 0.5 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain ECH PF00378.15 KUM56121.1 - 6.6e-27 94.2 0.0 8.8e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Hist_deacetyl PF00850.14 KUM56123.1 - 1.4e-58 198.6 0.0 1.9e-58 198.1 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Ala_racemase_N PF01168.15 KUM56125.1 - 3.4e-43 147.7 0.0 4.2e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Adaptin_N PF01602.15 KUM56126.1 - 9.8e-125 416.8 4.0 1.2e-124 416.5 2.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 KUM56126.1 - 1e-42 144.6 0.0 2.4e-42 143.4 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 KUM56126.1 - 2.1e-19 69.9 0.0 5.4e-19 68.5 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain DUF1096 PF06493.6 KUM56127.1 - 3.1 7.8 48.4 0.58 10.1 13.4 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1096) Homeobox PF00046.24 KUM56128.1 - 3.9e-17 61.5 3.1 1.8e-16 59.4 2.7 1.7 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 KUM56128.1 - 0.029 14.0 0.2 0.071 12.8 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain Sugar_tr PF00083.19 KUM56129.1 - 2.7e-76 256.9 22.0 3.3e-76 256.6 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM56129.1 - 1.2e-17 63.7 51.0 5.9e-17 61.4 15.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SnoaL_4 PF13577.1 KUM56130.1 - 2.4e-05 24.2 0.5 3.8e-05 23.5 0.3 1.3 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 KUM56130.1 - 0.006 16.6 0.3 0.032 14.2 0.2 1.9 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 KUM56130.1 - 0.019 15.1 0.1 0.019 15.1 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 KUM56130.1 - 0.029 14.7 0.4 0.045 14.1 0.3 1.5 1 1 0 1 1 1 0 SnoaL-like domain CDC14 PF08045.6 KUM56131.1 - 2.4e-95 318.5 0.0 2.7e-95 318.3 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component polyprenyl_synt PF00348.12 KUM56132.1 - 8e-58 195.3 0.0 9.7e-58 195.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 KUM56132.1 - 0.026 13.7 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain DUF2731 PF10806.3 KUM56133.1 - 2.1e-06 28.0 0.1 6.3e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2731) Tom37 PF10568.4 KUM56133.1 - 5.7e-05 23.2 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_3 PF14497.1 KUM56133.1 - 0.0078 16.6 0.1 0.015 15.7 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37_C PF11801.3 KUM56133.1 - 0.01 15.7 0.0 0.12 12.2 0.1 2.0 2 0 0 2 2 2 0 Tom37 C-terminal domain Methyltransf_18 PF12847.2 KUM56134.1 - 4.2e-08 33.7 0.0 9.2e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM56134.1 - 5.4e-07 29.3 0.0 8.8e-07 28.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM56134.1 - 6.2e-06 26.0 0.0 1.2e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM56134.1 - 1.4e-05 25.4 0.0 4.2e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM56134.1 - 2e-05 24.9 0.0 3.8e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM56134.1 - 2.4e-05 24.6 0.0 5.7e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 KUM56134.1 - 0.002 17.8 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KUM56134.1 - 0.012 14.7 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TehB PF03848.9 KUM56134.1 - 0.049 12.7 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB CheR PF01739.13 KUM56134.1 - 0.067 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain DUF1771 PF08590.5 KUM56135.1 - 1.6e-25 88.9 5.6 4.8e-25 87.3 3.9 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 KUM56135.1 - 4.1e-16 58.9 0.3 1.1e-15 57.6 0.2 1.7 1 0 0 1 1 1 1 Smr domain G-alpha PF00503.15 KUM56136.1 - 1.1e-134 449.0 2.3 1.4e-134 448.7 1.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KUM56136.1 - 1.9e-15 56.5 1.6 2e-10 40.1 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 KUM56136.1 - 8.5e-05 22.0 0.0 0.00037 19.9 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 KUM56136.1 - 0.0012 19.3 0.7 2.4 8.6 0.1 2.9 2 2 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 KUM56136.1 - 0.0063 15.6 3.6 0.14 11.2 0.1 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 KUM56136.1 - 0.0097 15.4 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 KUM56136.1 - 0.021 14.2 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.1 KUM56136.1 - 0.057 13.7 0.3 0.12 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain MCM PF00493.18 KUM56136.1 - 0.082 11.6 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family MMR_HSR1 PF01926.18 KUM56136.1 - 0.096 12.6 0.0 15 5.5 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KUM56136.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Copper-fist PF00649.13 KUM56137.1 - 1.3e-19 69.0 0.3 4.5e-19 67.3 0.2 2.0 1 0 0 1 1 1 1 Copper fist DNA binding domain OPT PF03169.10 KUM56138.1 - 1.2e-162 542.6 55.2 1.3e-162 542.4 38.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein E1-E2_ATPase PF00122.15 KUM56138.1 - 9.9 5.1 7.5 1.1 8.2 1.6 1.9 2 0 0 2 2 2 0 E1-E2 ATPase Transp_cyt_pur PF02133.10 KUM56139.1 - 1.4e-22 79.8 36.8 2.9e-22 78.8 25.5 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin KCNQ_channel PF03520.9 KUM56139.1 - 0.087 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 KCNQ voltage-gated potassium channel TrbC PF04956.8 KUM56139.1 - 6.9 6.7 17.0 0.073 13.0 4.0 3.2 3 0 0 3 3 3 0 TrbC/VIRB2 family Ank_2 PF12796.2 KUM56140.1 - 1.8e-49 165.9 0.1 4.6e-19 68.5 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KUM56140.1 - 4.9e-45 149.1 2.3 4.9e-06 26.0 0.0 8.3 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.1 KUM56140.1 - 2.3e-42 142.6 0.6 2.4e-11 43.8 0.0 6.1 5 1 1 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM56140.1 - 1.3e-39 133.2 2.3 3.8e-09 36.4 0.0 7.9 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM56140.1 - 1.6e-33 111.3 1.0 0.0028 17.7 0.0 8.3 8 0 0 8 8 8 8 Ankyrin repeat DUF2183 PF09949.4 KUM56141.1 - 1.2e-18 66.8 0.1 2.1e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) GLE1 PF07817.8 KUM56143.1 - 1.6e-12 46.9 0.0 1.6e-12 46.9 0.0 3.3 3 1 1 4 4 4 2 GLE1-like protein Borrelia_P83 PF05262.6 KUM56143.1 - 0.98 7.6 31.3 1.5 7.0 21.7 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein SOBP PF15279.1 KUM56143.1 - 2.8 8.2 7.1 4.4 7.6 5.0 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein CAF-1_p150 PF11600.3 KUM56143.1 - 6 6.1 52.1 10 5.4 36.1 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Macoilin PF09726.4 KUM56144.1 - 5.2 5.2 15.4 5.3 5.1 10.7 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF566 PF04484.7 KUM56144.1 - 8.2 5.8 15.7 9.2 5.6 10.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) UQ_con PF00179.21 KUM56145.1 - 2.7e-34 117.5 0.0 4.6e-34 116.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KUM56145.1 - 0.00013 21.7 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KUM56145.1 - 0.099 12.5 0.0 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 RWD domain RNB PF00773.14 KUM56146.1 - 9.7e-81 271.5 0.1 2.6e-79 266.8 0.0 2.3 2 0 0 2 2 2 2 RNB domain MIP PF00230.15 KUM56147.1 - 3.8e-45 154.1 10.9 5e-45 153.7 7.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein SKG6 PF08693.5 KUM56148.1 - 3.8e-06 26.1 0.0 3.8e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Podoplanin PF05808.6 KUM56148.1 - 0.002 17.6 0.0 0.0027 17.2 0.0 1.2 1 0 0 1 1 1 1 Podoplanin Mid2 PF04478.7 KUM56148.1 - 0.054 12.9 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Abhydrolase_3 PF07859.8 KUM56149.1 - 2.2e-43 148.2 0.0 3e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KUM56149.1 - 2.3e-07 29.9 0.3 6.6e-07 28.4 0.2 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KUM56149.1 - 0.0044 16.7 0.0 0.0054 16.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KUM56149.1 - 0.028 13.6 0.0 3 6.9 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF2974 PF11187.3 KUM56149.1 - 0.044 13.1 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Thioesterase PF00975.15 KUM56149.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain tRNA-synt_2 PF00152.15 KUM56150.1 - 1.1e-74 251.1 0.0 1.8e-74 250.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 KUM56150.1 - 1.4e-18 66.7 0.0 2e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 KUM56150.1 - 0.0018 18.1 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KUM56150.1 - 0.0055 15.9 0.1 3.4 6.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Tubulin PF00091.20 KUM56152.1 - 2.2e-69 233.6 0.0 3e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KUM56152.1 - 4.5e-48 162.4 0.0 8.1e-48 161.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KUM56152.1 - 0.001 18.5 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain MFS_1 PF07690.11 KUM56154.1 - 4.1e-18 65.2 45.5 4.1e-18 65.2 31.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM56154.1 - 0.00038 19.1 6.6 0.00038 19.1 4.6 2.9 2 1 1 3 3 3 1 Sugar (and other) transporter VIT1 PF01988.14 KUM56154.1 - 0.16 11.4 0.2 0.16 11.4 0.1 4.7 3 2 3 7 7 7 0 VIT family AA_permease PF00324.16 KUM56155.1 - 1.1e-124 416.4 48.8 1.3e-124 416.1 33.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KUM56155.1 - 3.6e-31 108.1 53.0 4.4e-31 107.8 36.7 1.0 1 0 0 1 1 1 1 Amino acid permease MgtE PF01769.11 KUM56155.1 - 0.41 10.9 0.0 0.41 10.9 0.0 4.1 4 1 1 5 5 5 0 Divalent cation transporter Acyl-CoA_dh_M PF02770.14 KUM56156.1 - 1.6e-18 65.9 0.3 2.8e-18 65.1 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 KUM56156.1 - 1.2e-16 61.1 0.7 2.3e-16 60.2 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 KUM56156.1 - 3.8e-07 30.4 0.3 8e-07 29.3 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 KUM56156.1 - 0.0049 16.2 0.0 0.0072 15.7 0.0 1.2 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF1540 PF07561.6 KUM56156.1 - 0.035 14.1 0.1 0.09 12.8 0.1 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1540) p450 PF00067.17 KUM56157.1 - 9.5e-53 179.3 0.1 1.3e-52 178.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 KUM56158.1 - 1.3e-51 170.7 12.3 7.5e-09 35.1 0.0 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 KUM56158.1 - 1.5e-13 50.2 0.3 3.9e-13 48.8 0.2 1.8 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 KUM56158.1 - 9.2e-12 43.8 11.2 0.019 13.1 0.2 5.2 2 1 3 5 5 5 5 Nucleoporin Nup120/160 F-box PF00646.28 KUM56158.1 - 1.2e-10 40.7 0.7 4.2e-10 39.0 0.1 2.2 2 0 0 2 2 2 1 F-box domain Elongin_A PF06881.6 KUM56158.1 - 0.15 12.4 0.9 0.52 10.7 0.0 2.3 3 0 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A CHASE PF03924.8 KUM56159.1 - 0.09 11.9 0.1 0.09 11.9 0.0 1.0 1 0 0 1 1 1 0 CHASE domain Methyltransf_2 PF00891.13 KUM56160.1 - 8.9e-09 34.8 2.1 2.5e-07 30.1 0.3 2.0 2 0 0 2 2 2 2 O-methyltransferase Methyltransf_2 PF00891.13 KUM56161.1 - 3.8e-15 55.7 0.1 4.3e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase SMC_N PF02463.14 KUM56162.1 - 2.4e-72 242.7 2.3 3.7e-72 242.1 1.6 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KUM56162.1 - 5.5e-33 113.4 1.2 4.6e-32 110.5 0.0 3.2 4 0 0 4 4 4 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 KUM56162.1 - 1.1e-18 68.3 3.7 1.1e-18 68.3 2.6 6.6 2 2 2 5 5 3 1 AAA domain AAA_21 PF13304.1 KUM56162.1 - 1.2e-18 68.1 1.0 1.3e-09 38.4 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KUM56162.1 - 1.6e-10 40.5 22.3 4.1e-09 35.9 1.1 3.2 2 2 0 2 2 2 2 AAA ATPase domain APG6 PF04111.7 KUM56162.1 - 0.0003 19.9 6.0 0.0003 19.9 4.1 7.2 2 2 4 7 7 7 3 Autophagy protein Apg6 AAA_29 PF13555.1 KUM56162.1 - 0.00033 20.1 0.0 0.00076 18.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF4201 PF13870.1 KUM56162.1 - 0.0041 16.5 11.0 0.0041 16.5 7.6 7.4 4 1 2 7 7 7 3 Domain of unknown function (DUF4201) FliD_N PF02465.13 KUM56162.1 - 0.012 15.9 2.7 0.012 15.9 1.9 7.3 4 3 4 8 8 8 0 Flagellar hook-associated protein 2 N-terminus Reo_sigmaC PF04582.7 KUM56162.1 - 0.17 11.0 32.3 0.22 10.6 1.4 5.5 3 2 3 7 7 7 0 Reovirus sigma C capsid protein FtsK_SpoIIIE PF01580.13 KUM56162.1 - 0.26 10.7 0.0 0.26 10.7 0.0 4.3 4 2 1 5 5 5 0 FtsK/SpoIIIE family IncA PF04156.9 KUM56162.1 - 1.1 8.7 105.8 0.3 10.6 13.5 6.9 3 2 2 6 6 6 0 IncA protein AAA_13 PF13166.1 KUM56162.1 - 2 6.7 88.1 0.02 13.3 9.3 6.8 3 2 3 7 7 7 0 AAA domain RIO1 PF01163.17 KUM56163.1 - 1.8e-72 242.6 0.1 1.8e-72 242.6 0.0 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 KUM56163.1 - 9.5e-05 22.2 0.0 0.078 12.7 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KUM56163.1 - 0.0016 17.5 0.2 0.033 13.2 0.1 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APG17 PF04108.7 KUM56164.1 - 2.2e-128 428.6 0.1 2.5e-128 428.4 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF4358 PF14270.1 KUM56164.1 - 0.022 14.6 0.7 0.057 13.2 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) LXG PF04740.7 KUM56164.1 - 0.28 10.9 7.4 3 7.5 0.1 3.4 2 1 0 3 3 3 0 LXG domain of WXG superfamily Flu_NS2 PF00601.14 KUM56164.1 - 4.4 7.5 5.7 36 4.6 0.0 3.9 4 0 0 4 4 4 0 Influenza non-structural protein (NS2) DUF2293 PF10056.4 KUM56164.1 - 7.2 6.6 8.2 5.3 7.0 0.3 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2293) Syntaxin-6_N PF09177.6 KUM56164.1 - 8.8 6.8 9.0 12 6.4 0.2 3.8 2 2 1 4 4 4 0 Syntaxin 6, N-terminal 5_nucleotid_C PF02872.13 KUM56166.1 - 0.021 14.7 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain FA_hydroxylase PF04116.8 KUM56167.1 - 2.2e-16 60.2 19.5 2.2e-16 60.2 13.5 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily p450 PF00067.17 KUM56168.1 - 4.5e-65 219.9 0.0 5.3e-65 219.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TPR_12 PF13424.1 KUM56169.1 - 6.4e-32 109.3 2.2 7.2e-08 32.2 0.1 5.5 2 1 2 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 KUM56169.1 - 2.9e-24 84.2 0.0 0.00021 21.1 0.0 8.6 8 0 0 8 8 8 4 Tetratricopeptide repeat NB-ARC PF00931.17 KUM56169.1 - 3.5e-08 32.6 0.0 9e-08 31.3 0.0 1.7 1 1 0 1 1 1 1 NB-ARC domain TPR_19 PF14559.1 KUM56169.1 - 7.2e-05 23.0 0.4 26 5.2 0.1 5.4 4 1 1 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 KUM56169.1 - 0.0013 18.7 0.1 4.7 7.4 0.0 4.7 2 2 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF676 PF05057.9 KUM56169.1 - 0.0017 17.6 0.1 0.004 16.4 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_22 PF13401.1 KUM56169.1 - 0.0031 17.6 0.0 0.019 15.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain PGAP1 PF07819.8 KUM56169.1 - 0.015 14.8 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein TPR_11 PF13414.1 KUM56169.1 - 0.025 14.2 0.0 2.6 7.7 0.0 3.4 3 0 0 3 3 3 0 TPR repeat TPR_16 PF13432.1 KUM56169.1 - 0.034 14.8 0.2 11 6.7 0.1 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat PS-DH PF14765.1 KUM56170.1 - 6.2e-61 206.1 0.1 1.1e-60 205.3 0.1 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 KUM56170.1 - 5.2e-57 192.4 2.1 1.2e-56 191.2 0.9 2.1 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 KUM56170.1 - 6.2e-55 186.7 0.0 1e-54 186.0 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 KUM56170.1 - 7.9e-45 152.7 1.4 7.9e-45 152.7 1.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.21 KUM56170.1 - 8.5e-16 57.6 0.0 2.5e-15 56.1 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KUM56170.1 - 3.7e-10 39.7 0.0 1.8e-09 37.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM56170.1 - 4.8e-10 39.8 0.0 1.3e-09 38.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KUM56170.1 - 1.4e-05 25.2 0.0 4.7e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 KUM56170.1 - 3.7e-05 23.3 0.0 9.8e-05 21.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM56170.1 - 0.00011 22.6 0.0 0.0005 20.5 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM56170.1 - 0.043 14.3 0.0 0.14 12.7 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain ADH_N PF08240.7 KUM56170.1 - 0.088 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.13 KUM56170.1 - 0.12 11.4 0.0 0.34 9.9 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family UDPG_MGDP_dh_C PF03720.10 KUM56170.1 - 0.13 12.3 0.1 0.45 10.6 0.0 1.9 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain ketoacyl-synt PF00109.21 KUM56171.1 - 2.2e-74 250.1 0.0 2.7e-74 249.8 0.0 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KUM56171.1 - 2.3e-20 72.6 0.0 4.8e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.5 KUM56171.1 - 0.0012 18.4 0.4 0.0024 17.4 0.3 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 KUM56171.1 - 0.0086 15.0 0.1 0.015 14.3 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain GMC_oxred_N PF00732.14 KUM56172.1 - 1.5e-12 47.3 0.0 2e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase DUF3224 PF11528.3 KUM56172.1 - 0.091 12.2 0.1 3 7.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3224) DEAD PF00270.24 KUM56173.1 - 1.8e-45 154.4 0.0 1.4e-43 148.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM56173.1 - 9.3e-28 95.9 0.0 2.2e-27 94.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KUM56173.1 - 0.0019 18.0 0.0 0.0052 16.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 KUM56173.1 - 0.0029 17.5 0.0 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DUF1253 PF06862.7 KUM56173.1 - 0.028 12.8 0.0 0.63 8.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) DUF2443 PF10398.4 KUM56173.1 - 0.07 12.9 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) AAA_22 PF13401.1 KUM56173.1 - 0.11 12.6 0.6 3.7 7.7 0.1 3.1 1 1 1 2 2 2 0 AAA domain POTRA_2 PF08479.6 KUM56173.1 - 0.12 12.0 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 POTRA domain, ShlB-type DUF632 PF04782.7 KUM56174.1 - 0.055 12.5 0.3 0.065 12.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF632) Herpes_BLLF1 PF05109.8 KUM56174.1 - 0.17 9.8 5.7 0.19 9.6 3.9 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) APC_CDC26 PF10471.4 KUM56175.1 - 2.8 8.7 7.9 0.21 12.3 1.6 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF3987 PF13148.1 KUM56175.1 - 5.5 5.4 8.9 8.3 4.8 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) adh_short_C2 PF13561.1 KUM56178.1 - 2.7e-24 86.2 0.1 3.6e-24 85.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KUM56178.1 - 4.7e-22 78.6 2.2 7e-22 78.1 1.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM56178.1 - 6.6e-08 32.4 3.4 3.3e-07 30.1 2.3 1.9 1 1 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 KUM56178.1 - 0.0047 16.0 0.4 0.013 14.7 0.2 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KUM56178.1 - 0.014 15.7 1.5 0.028 14.8 1.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 KUM56178.1 - 0.025 13.9 1.5 0.19 11.1 1.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_Gly3P_dh_N PF01210.18 KUM56178.1 - 0.043 13.5 1.4 0.1 12.3 0.6 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 KUM56178.1 - 0.058 13.0 1.2 0.091 12.4 0.8 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KUM56178.1 - 0.15 12.1 0.3 0.31 11.1 0.2 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PepSY_TM_2 PF13703.1 KUM56180.1 - 0.19 11.9 0.6 0.43 10.7 0.4 1.6 1 0 0 1 1 1 0 PepSY-associated TM helix Voldacs PF03517.8 KUM56181.1 - 1.6e-29 102.4 0.1 1.6e-29 102.4 0.1 1.7 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling NAD_binding_10 PF13460.1 KUM56182.1 - 3.7e-06 27.0 0.0 4.6e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KUM56182.1 - 0.00075 18.4 0.1 0.069 12.0 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 KUM56182.1 - 0.0016 17.2 0.0 0.002 16.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 KUM56182.1 - 0.073 12.9 0.1 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 KUM56182.1 - 0.084 11.7 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Phage_holin_3 PF05106.7 KUM56182.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) DUF3328 PF11807.3 KUM56183.1 - 0.063 12.9 0.0 0.078 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Dioxygenase_C PF00775.16 KUM56184.1 - 4.9e-44 149.7 0.0 6.4e-44 149.3 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KUM56184.1 - 1.6e-10 40.8 0.0 2.8e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Ring_hydroxyl_A PF00848.14 KUM56185.1 - 7.7e-30 104.1 1.2 2.7e-29 102.3 0.9 1.9 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 KUM56185.1 - 1.6e-15 56.4 0.0 3.4e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Amidohydro_3 PF07969.6 KUM56185.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase family FMN_bind_2 PF04299.7 KUM56186.1 - 1.1e-54 184.4 0.2 1.3e-54 184.2 0.1 1.0 1 0 0 1 1 1 1 Putative FMN-binding domain Herpes_pp38 PF04846.8 KUM56187.1 - 0.012 14.8 0.4 0.025 13.8 0.3 1.5 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein HemY_N PF07219.8 KUM56187.1 - 0.12 11.9 1.0 0.35 10.4 0.7 1.9 1 0 0 1 1 1 0 HemY protein N-terminus ABC2_membrane_5 PF13346.1 KUM56187.1 - 0.14 11.4 0.1 0.2 10.9 0.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DNA_pol_lambd_f PF10391.4 KUM56189.1 - 3.6e-23 80.8 0.7 6.6e-23 80.0 0.5 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 KUM56189.1 - 1.8e-18 65.9 0.1 1.2e-17 63.2 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 KUM56189.1 - 5.9e-16 58.5 0.1 1.9e-15 56.9 0.1 1.9 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 KUM56189.1 - 6e-09 35.9 0.0 3.7e-08 33.4 0.0 2.4 4 0 0 4 4 4 1 Helix-hairpin-helix domain HHH_5 PF14520.1 KUM56189.1 - 0.0005 20.1 0.0 0.022 14.9 0.0 2.9 3 0 0 3 3 3 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 KUM56189.1 - 0.038 14.3 0.1 0.093 13.0 0.1 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain HAD PF12710.2 KUM56190.1 - 1.6e-17 64.3 0.1 4e-17 63.0 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KUM56190.1 - 1e-15 57.4 0.1 1.7e-15 56.7 0.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KUM56190.1 - 2.6e-14 54.1 0.0 1.6e-13 51.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KUM56190.1 - 2.2e-11 43.5 0.0 6e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KUM56190.1 - 0.0037 16.8 0.1 0.014 15.0 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KUM56190.1 - 0.017 15.3 0.1 0.083 13.1 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase RNase_PH PF01138.16 KUM56191.1 - 5.8e-17 62.2 0.0 9.5e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KUM56191.1 - 4.5e-05 23.3 0.0 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.7 KUM56192.1 - 7.9e-84 281.1 15.2 8.9e-84 281.0 10.6 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.7 KUM56192.1 - 3.2 6.9 22.0 3.7 6.7 15.2 1.1 1 0 0 1 1 1 0 SDA1 DUF4519 PF15012.1 KUM56192.1 - 5.1 7.0 6.4 8.3 6.4 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) CDC45 PF02724.9 KUM56192.1 - 5.5 4.9 18.2 6.8 4.5 12.6 1.1 1 0 0 1 1 1 0 CDC45-like protein APG6 PF04111.7 KUM56192.1 - 7.6 5.4 8.7 10 5.0 6.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1510 PF07423.6 KUM56192.1 - 7.8 5.7 15.2 11 5.3 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RPA_interact_M PF14767.1 KUM56192.1 - 8.8 7.1 19.3 17 6.2 13.1 1.7 2 0 0 2 2 2 0 Replication protein A interacting middle SAM_2 PF07647.12 KUM56193.1 - 0.037 13.8 0.0 7.3 6.5 0.0 2.2 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Act-Frag_cataly PF09192.5 KUM56194.1 - 0.043 12.7 0.2 0.077 11.9 0.1 1.3 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic DUF2393 PF09624.5 KUM56194.1 - 0.11 12.0 2.2 0.59 9.6 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2393) Ripply PF14998.1 KUM56194.1 - 3.5 7.8 5.3 3.7 7.7 0.1 3.0 2 1 1 3 3 3 0 Transcription Regulator RCC_reductase PF06405.6 KUM56194.1 - 6.4 5.6 7.0 2.3 7.0 1.1 2.2 1 1 1 2 2 2 0 Red chlorophyll catabolite reductase (RCC reductase) AFP PF02420.10 KUM56195.1 - 0.024 14.7 2.8 1.1e+02 3.4 0.0 4.3 4 0 0 4 4 4 0 Insect antifreeze protein repeat DUF43 PF01861.11 KUM56195.1 - 0.044 12.7 0.1 0.53 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF43 Acetyltransf_7 PF13508.1 KUM56196.1 - 1.6e-06 28.1 0.0 4.8e-06 26.6 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KUM56196.1 - 4.7e-05 23.4 0.0 8.9e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KUM56196.1 - 0.00011 22.1 0.0 0.00027 20.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KUM56196.1 - 0.13 12.1 0.0 0.29 10.9 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Fungal_trans PF04082.13 KUM56198.1 - 0.0021 16.9 0.0 0.0036 16.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KUM56199.1 - 1.3e-42 145.7 52.9 1.3e-42 145.7 33.8 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM56199.1 - 2.1e-12 46.0 24.4 2.8e-12 45.6 16.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KUM56199.1 - 5.1e-08 31.9 5.8 5.1e-08 31.9 4.0 3.7 4 0 0 4 4 4 1 Sugar (and other) transporter Phage_Coat_Gp8 PF05371.7 KUM56200.1 - 0.47 10.0 5.6 2.2 7.8 0.2 2.8 2 0 0 2 2 2 0 Phage major coat protein, Gp8 AA_permease_2 PF13520.1 KUM56201.1 - 1.3e-42 145.8 51.2 1.6e-42 145.5 35.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM56201.1 - 2.5e-20 72.2 47.0 5.3e-20 71.2 32.6 1.4 1 1 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.19 KUM56202.1 - 2.2e-103 346.2 38.2 2.5e-103 346.0 26.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM56202.1 - 1.2e-29 103.1 35.7 1.2e-29 103.1 24.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_1 PF00583.19 KUM56203.1 - 1.2e-09 38.1 0.0 1.7e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KUM56203.1 - 7.3e-08 32.4 0.0 1.1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KUM56203.1 - 1.7e-06 28.1 0.0 3.5e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KUM56203.1 - 0.028 14.2 0.0 0.5 10.2 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.1 KUM56205.1 - 2.4e-44 151.5 57.0 2.9e-44 151.2 39.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM56205.1 - 7.9e-20 70.6 48.0 1e-19 70.3 33.3 1.0 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_2 PF00797.12 KUM56206.1 - 2.2e-43 148.5 0.0 4e-43 147.7 0.0 1.4 1 1 0 1 1 1 1 N-acetyltransferase zf-met2 PF12907.2 KUM56208.1 - 1.4e-17 63.3 0.5 2.1e-17 62.8 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 KUM56208.1 - 9.8e-07 29.4 12.9 9.8e-07 29.4 8.9 1.5 2 0 0 2 2 2 1 4F5 protein family eIF3g PF12353.3 KUM56208.1 - 0.067 13.1 1.3 0.082 12.8 0.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G DUF1644 PF07800.7 KUM56208.1 - 0.099 12.4 1.0 0.12 12.2 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) CLAG PF03805.8 KUM56208.1 - 0.38 8.0 1.6 0.4 7.9 1.1 1.0 1 0 0 1 1 1 0 Cytoadherence-linked asexual protein Glyco_hydro_72 PF03198.9 KUM56209.1 - 2.1e-126 421.1 3.9 2.8e-126 420.7 2.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 KUM56209.1 - 7.9e-27 93.5 8.8 1.8e-26 92.4 6.1 1.7 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.12 KUM56209.1 - 0.0009 18.2 0.2 0.0032 16.4 0.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 KUM56209.1 - 0.0013 18.0 0.2 0.012 14.8 0.1 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2164 PF09932.4 KUM56209.1 - 0.18 11.5 0.1 0.45 10.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2164) OppC_N PF12911.2 KUM56209.1 - 0.49 9.7 3.2 1.6 8.1 2.2 1.8 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C adh_short_C2 PF13561.1 KUM56210.1 - 6.5e-24 85.0 0.0 1e-23 84.3 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KUM56210.1 - 2.5e-19 69.7 0.0 3.3e-18 66.1 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM56210.1 - 4.7e-06 26.3 0.0 5.6e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KUM56210.1 - 0.0095 15.3 0.0 0.032 13.6 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Gly_transf_sug PF04488.10 KUM56211.1 - 5e-09 36.4 0.0 8.4e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif P2X_receptor PF00864.14 KUM56211.1 - 0.15 10.7 0.0 0.28 9.8 0.0 1.3 1 0 0 1 1 1 0 ATP P2X receptor PH PF00169.24 KUM56212.1 - 0.017 15.3 0.0 0.039 14.1 0.0 1.7 1 0 0 1 1 1 0 PH domain DAO PF01266.19 KUM56214.1 - 6.8e-54 183.1 0.0 7.9e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KUM56214.1 - 7.4e-07 29.1 0.0 2.4e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KUM56214.1 - 5.2e-05 22.2 0.0 0.029 13.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 KUM56214.1 - 0.00025 21.1 0.0 0.0056 16.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KUM56214.1 - 0.00053 19.9 0.0 0.014 15.2 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM56214.1 - 0.00094 18.9 0.0 0.26 11.0 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding GIDA PF01134.17 KUM56214.1 - 0.00096 18.1 0.3 0.027 13.3 0.0 2.4 2 1 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KUM56214.1 - 0.0033 16.5 0.0 0.0053 15.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KUM56214.1 - 0.0039 17.5 0.0 0.0084 16.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KUM56214.1 - 0.034 14.1 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.15 KUM56214.1 - 0.052 13.6 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 KUM56214.1 - 0.1 11.6 0.1 0.4 9.7 0.0 1.8 2 0 0 2 2 2 0 Thi4 family ThiF PF00899.16 KUM56214.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 ThiF family SNARE PF05739.14 KUM56215.1 - 0.02 14.5 0.3 0.027 14.1 0.2 1.2 1 0 0 1 1 1 0 SNARE domain Rootletin PF15035.1 KUM56215.1 - 0.05 13.5 0.2 0.053 13.4 0.1 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Arrestin_C PF02752.17 KUM56217.1 - 1.8e-18 66.9 0.0 5.2e-18 65.4 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KUM56217.1 - 4.6e-15 55.7 0.0 7.9e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 KUM56217.1 - 0.0022 17.4 0.0 0.0048 16.4 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like Condensation PF00668.15 KUM56218.1 - 7e-46 156.4 0.0 9.4e-46 156.0 0.0 1.2 1 0 0 1 1 1 1 Condensation domain Condensation PF00668.15 KUM56219.1 - 3.1e-37 128.0 0.1 4.6e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 KUM56219.1 - 7.7e-09 35.6 0.0 1.5e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site NCA2 PF08637.5 KUM56220.1 - 9.3e-58 195.4 0.0 1.8e-57 194.4 0.0 1.4 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Ribosomal_L22 PF00237.14 KUM56221.1 - 0.043 13.7 0.0 0.73 9.8 0.0 2.4 2 1 0 2 2 2 0 Ribosomal protein L22p/L17e IncA PF04156.9 KUM56223.1 - 0.0013 18.3 0.3 0.0016 18.0 0.2 1.1 1 0 0 1 1 1 1 IncA protein TMF_DNA_bd PF12329.3 KUM56223.1 - 0.0017 18.1 0.9 0.0024 17.6 0.2 1.6 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding Med9 PF07544.8 KUM56223.1 - 0.0034 17.0 0.3 0.0059 16.3 0.2 1.6 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 RBD-FIP PF09457.5 KUM56223.1 - 0.0077 16.0 0.5 0.014 15.1 0.3 1.5 1 0 0 1 1 1 1 FIP domain DASH_Spc34 PF08657.5 KUM56223.1 - 0.017 14.7 0.1 0.02 14.6 0.1 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 AAA_13 PF13166.1 KUM56223.1 - 0.022 13.2 0.0 0.025 13.0 0.0 1.0 1 0 0 1 1 1 0 AAA domain DUF4140 PF13600.1 KUM56223.1 - 0.028 14.8 0.1 0.037 14.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) NTR2 PF15458.1 KUM56223.1 - 0.031 13.5 0.1 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 Nineteen complex-related protein 2 Prefoldin_2 PF01920.15 KUM56223.1 - 0.036 13.8 0.3 0.056 13.2 0.2 1.3 1 0 0 1 1 1 0 Prefoldin subunit NPV_P10 PF05531.7 KUM56223.1 - 0.051 13.8 0.4 0.26 11.5 0.1 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein FTA4 PF13093.1 KUM56223.1 - 0.095 12.1 0.1 0.11 11.8 0.1 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Atg14 PF10186.4 KUM56223.1 - 0.1 11.5 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Reo_sigmaC PF04582.7 KUM56223.1 - 0.12 11.5 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Nup54 PF13874.1 KUM56223.1 - 0.14 11.8 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Med21 PF11221.3 KUM56223.1 - 0.15 12.0 0.7 0.2 11.6 0.5 1.1 1 0 0 1 1 1 0 Subunit 21 of Mediator complex RmlD_sub_bind PF04321.12 KUM56225.1 - 4.8e-56 189.7 0.0 6.1e-56 189.4 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 KUM56225.1 - 2.1e-23 83.0 0.0 4.6e-23 81.8 0.0 1.6 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KUM56225.1 - 2.9e-14 52.5 0.0 7.8e-12 44.6 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 KUM56225.1 - 9.4e-13 47.4 0.1 6.6e-12 44.7 0.1 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KUM56225.1 - 2.5e-12 46.2 0.2 3.1e-08 32.8 0.0 3.1 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KUM56225.1 - 8.3e-06 25.9 0.0 1.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KUM56225.1 - 0.00025 21.0 0.0 0.024 14.5 0.0 2.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM56225.1 - 0.078 12.6 0.3 17 5.0 0.0 2.8 3 0 0 3 3 3 0 KR domain Glyco_hydro_16 PF00722.16 KUM56227.1 - 2.8e-07 30.0 0.0 6e-07 28.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 ASRT PF07100.6 KUM56227.1 - 0.06 13.1 0.2 7 6.4 0.0 2.3 2 0 0 2 2 2 0 Anabaena sensory rhodopsin transducer RA PF00788.18 KUM56229.1 - 0.00012 22.5 0.0 0.0004 20.7 0.0 1.9 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PH PF00169.24 KUM56229.1 - 0.007 16.5 1.4 0.024 14.8 0.9 1.9 1 1 0 1 1 1 1 PH domain TUG-UBL1 PF11470.3 KUM56229.1 - 0.075 12.9 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 GLUT4 regulating protein TUG Phage-tail_2 PF09096.5 KUM56229.1 - 0.083 12.5 0.1 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Baseplate structural protein, domain 2 FAD-oxidase_C PF02913.14 KUM56230.1 - 5.1e-57 193.0 0.0 7.8e-57 192.4 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KUM56230.1 - 7.4e-36 122.6 0.4 1.4e-35 121.7 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pkinase PF00069.20 KUM56231.1 - 2.7e-70 236.4 0.0 3.7e-70 236.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM56231.1 - 4.3e-47 160.3 0.0 6e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM56231.1 - 6.1e-05 22.1 0.0 0.0003 19.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like MFS_1 PF07690.11 KUM56232.1 - 4.6e-29 101.2 31.3 4.6e-29 101.2 21.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM56232.1 - 1.8e-09 36.6 16.2 1.8e-09 36.6 11.3 2.9 3 1 0 3 3 3 2 Sugar (and other) transporter Senescence PF06911.7 KUM56233.1 - 7.9e-48 162.5 4.2 1.1e-47 162.0 2.9 1.2 1 0 0 1 1 1 1 Senescence-associated protein SIMPL PF04402.9 KUM56234.1 - 6.8e-30 104.4 0.0 8.2e-30 104.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Fungal_trans PF04082.13 KUM56235.1 - 1.1e-18 67.0 0.2 1.6e-18 66.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 KUM56236.1 - 3e-72 243.6 0.0 8.1e-72 242.2 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 KUM56236.1 - 0.0093 16.3 0.0 0.27 11.6 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase rve PF00665.21 KUM56237.1 - 2.8e-06 27.4 0.1 8.7e-06 25.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 KUM56237.1 - 3e-06 26.7 0.1 9.2e-06 25.2 0.1 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain NAD_binding_2 PF03446.10 KUM56238.1 - 2.3e-20 73.0 0.1 3.6e-20 72.4 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KUM56238.1 - 2.2e-06 27.7 0.0 4.1e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase His_Phos_1 PF00300.17 KUM56239.1 - 1.7e-16 60.7 0.0 2.1e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PD40 PF07676.7 KUM56241.1 - 4.3e-41 137.9 25.8 8.8e-07 28.4 0.3 10.3 9 1 1 10 10 10 9 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 KUM56241.1 - 3.6e-12 45.5 7.0 0.0079 14.8 0.1 6.7 5 2 1 7 7 7 6 Dipeptidyl peptidase IV (DPP IV) N-terminal region WD40 PF00400.27 KUM56241.1 - 2.2 8.3 8.9 42 4.2 0.0 5.3 7 0 0 7 7 7 0 WD domain, G-beta repeat MFS_1 PF07690.11 KUM56242.1 - 1.8e-21 76.3 56.6 1.8e-21 76.3 39.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Peroxidase_2 PF01328.12 KUM56243.1 - 9.3e-15 54.0 0.0 2.9e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 Peroxidase, family 2 DUF829 PF05705.9 KUM56244.1 - 2.1e-62 210.9 0.0 2.5e-62 210.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_1 PF00561.15 KUM56244.1 - 0.0011 18.5 0.0 0.027 14.0 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KUM56244.1 - 0.0014 18.5 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family CN_hydrolase PF00795.17 KUM56245.1 - 1.8e-24 86.1 0.0 2.6e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase LysR_substrate PF03466.15 KUM56245.1 - 0.051 12.6 0.0 1.3 8.1 0.0 2.6 3 0 0 3 3 3 0 LysR substrate binding domain HlyIII PF03006.15 KUM56246.1 - 2.7e-18 66.1 12.0 3.6e-18 65.8 8.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related CRCB PF02537.10 KUM56246.1 - 0.056 13.3 5.9 0.13 12.1 3.8 1.7 2 1 0 2 2 2 0 CrcB-like protein Prok-E2_C PF14459.1 KUM56246.1 - 0.082 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family C DUF3522 PF12036.3 KUM56246.1 - 0.26 11.0 8.0 0.084 12.6 3.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3522) Lipoxygenase PF00305.14 KUM56247.1 - 6.4e-25 87.2 0.0 1e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 Lipoxygenase AIG2 PF06094.7 KUM56248.1 - 7.2e-13 48.9 0.3 1e-12 48.4 0.2 1.2 1 0 0 1 1 1 1 AIG2-like family Aldedh PF00171.17 KUM56249.1 - 6.9e-187 621.3 0.5 7.7e-187 621.2 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CP_ATPgrasp_2 PF14403.1 KUM56250.1 - 7.6e-05 21.5 0.0 0.0001 21.1 0.0 1.1 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 TTL PF03133.10 KUM56250.1 - 0.012 14.5 0.0 0.017 14.0 0.0 1.1 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family FAD_binding_3 PF01494.14 KUM56251.1 - 7.5e-15 54.8 1.8 5.7e-11 42.0 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KUM56251.1 - 1.3e-08 34.1 0.8 8.3e-08 31.5 0.2 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KUM56251.1 - 4.8e-08 32.9 0.3 1.4e-07 31.4 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KUM56251.1 - 6.6e-06 25.4 0.2 0.034 13.2 0.0 3.0 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 KUM56251.1 - 1.9e-05 23.6 1.9 0.00039 19.3 0.8 2.1 1 1 1 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KUM56251.1 - 4.3e-05 23.4 0.2 0.00013 21.8 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KUM56251.1 - 6e-05 22.1 0.1 8.2e-05 21.6 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 KUM56251.1 - 0.00036 20.8 0.5 0.0011 19.3 0.3 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KUM56251.1 - 0.0028 16.8 0.1 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KUM56251.1 - 0.0079 15.0 1.6 0.0079 15.0 1.1 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KUM56251.1 - 0.029 14.4 0.1 0.051 13.6 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.4 KUM56251.1 - 0.035 13.8 0.2 0.084 12.5 0.1 1.6 1 0 0 1 1 1 0 Rossmann-like domain 3HCDH_N PF02737.13 KUM56251.1 - 0.038 13.6 1.6 0.072 12.7 1.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KUM56251.1 - 0.043 13.5 0.7 0.074 12.7 0.5 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 KUM56251.1 - 0.047 13.5 0.1 0.099 12.4 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase HI0933_like PF03486.9 KUM56251.1 - 0.05 12.0 1.9 0.074 11.5 1.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 KUM56251.1 - 0.13 10.9 5.6 1.4 7.4 1.3 2.8 2 1 0 3 3 3 0 Tryptophan halogenase GFO_IDH_MocA PF01408.17 KUM56253.1 - 1.3e-24 87.0 0.1 2.4e-24 86.1 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KUM56253.1 - 9.8e-05 22.1 0.1 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_2 PF03446.10 KUM56253.1 - 0.0056 16.5 0.0 0.0091 15.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AAA_12 PF13087.1 KUM56254.1 - 1.1e-07 31.3 0.0 1.4e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain DUF3794 PF12673.2 KUM56255.1 - 0.031 14.4 0.0 0.05 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3794) Uma2 PF05685.7 KUM56256.1 - 0.0002 20.7 0.0 0.00037 19.8 0.0 1.4 1 0 0 1 1 1 1 Putative restriction endonuclease DUF2370 PF10176.4 KUM56257.1 - 0.071 12.4 0.0 0.071 12.4 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2370) Thiol_cytolysin PF01289.14 KUM56258.1 - 0.086 11.1 0.0 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 Thiol-activated cytolysin 4HBT_3 PF13622.1 KUM56260.1 - 8.4e-42 143.6 0.1 1.1e-41 143.3 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4082 PF13313.1 KUM56260.1 - 0.048 13.1 0.0 0.095 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) priB_priC PF07445.7 KUM56262.1 - 0.0037 16.7 1.4 0.0037 16.7 1.0 1.5 2 0 0 2 2 2 1 Primosomal replication protein priB and priC DUF2046 PF09755.4 KUM56262.1 - 0.0041 16.0 1.8 0.0041 16.0 1.3 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) DASH_Spc34 PF08657.5 KUM56262.1 - 0.053 13.1 2.3 2.8 7.5 1.9 2.1 2 0 0 2 2 2 0 DASH complex subunit Spc34 Nsp1_C PF05064.8 KUM56262.1 - 0.69 9.5 4.9 0.31 10.6 1.7 1.6 2 0 0 2 2 2 0 Nsp1-like C-terminal region DUF2968 PF11180.3 KUM56262.1 - 8.8 5.6 17.6 1.2 8.5 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) Sec62 PF03839.11 KUM56263.1 - 2.4e-57 193.9 0.3 2.4e-57 193.9 0.2 1.6 2 0 0 2 2 2 1 Translocation protein Sec62 MFS_1 PF07690.11 KUM56265.1 - 1.8e-23 82.8 27.5 1.2e-22 80.1 17.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily COesterase PF00135.23 KUM56267.1 - 3.2e-65 220.8 0.0 8.7e-39 133.6 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KUM56267.1 - 4.8e-08 32.8 0.1 2.8e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold SKG6 PF08693.5 KUM56268.1 - 0.0018 17.5 0.1 0.0051 16.0 0.1 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Plasmodium_Vir PF05795.6 KUM56268.1 - 0.0018 17.5 0.2 0.0025 17.1 0.1 1.1 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Glycophorin_A PF01102.13 KUM56268.1 - 0.0025 17.5 1.1 0.0041 16.8 0.8 1.3 1 0 0 1 1 1 1 Glycophorin A Mid2 PF04478.7 KUM56268.1 - 0.0064 15.9 0.5 0.011 15.2 0.3 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Herpes_gE PF02480.11 KUM56268.1 - 0.0066 14.7 0.1 0.0093 14.2 0.1 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF4366 PF14283.1 KUM56268.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Sporozoite_P67 PF05642.6 KUM56268.1 - 0.014 13.3 7.4 0.016 13.0 5.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Alpha_GJ PF03229.8 KUM56268.1 - 0.02 15.2 7.6 0.05 13.9 5.3 1.6 1 0 0 1 1 1 0 Alphavirus glycoprotein J RSN1_TM PF13967.1 KUM56268.1 - 0.025 14.1 0.1 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport EphA2_TM PF14575.1 KUM56268.1 - 0.045 14.1 0.0 0.089 13.1 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1517 PF07466.6 KUM56268.1 - 0.14 11.1 3.9 0.19 10.6 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF4381 PF14316.1 KUM56268.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) gpUL132 PF11359.3 KUM56268.1 - 0.15 11.4 6.1 0.23 10.7 4.2 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 RseC_MucC PF04246.7 KUM56268.1 - 0.47 10.0 2.1 22 4.6 0.0 2.5 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Pex14_N PF04695.8 KUM56268.1 - 0.98 9.4 7.1 0.32 11.0 1.1 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MGC-24 PF05283.6 KUM56268.1 - 1.2 8.9 23.4 2.3 7.9 16.2 1.4 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Med3 PF11593.3 KUM56268.1 - 2.9 7.0 12.1 4.5 6.4 8.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pheromone PF08015.6 KUM56268.1 - 9.2 7.1 12.5 25 5.7 8.7 1.8 1 0 0 1 1 1 0 Fungal mating-type pheromone PA26 PF04636.8 KUM56269.1 - 0.16 10.6 0.7 0.2 10.3 0.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) NmrA PF05368.8 KUM56270.1 - 2.2e-16 59.8 0.0 2.5e-16 59.6 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KUM56270.1 - 1.2e-09 38.4 0.2 1.3e-09 38.3 0.2 1.0 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KUM56270.1 - 0.00011 22.1 0.8 0.00015 21.7 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM56270.1 - 0.00026 20.7 0.5 0.00031 20.4 0.3 1.2 1 0 0 1 1 1 1 KR domain Glyco_trans_4_4 PF13579.1 KUM56270.1 - 0.0029 17.7 0.1 0.0033 17.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain ApbA PF02558.11 KUM56270.1 - 0.0069 15.8 0.2 0.015 14.7 0.1 1.6 1 1 1 2 2 2 1 Ketopantoate reductase PanE/ApbA PALP PF00291.20 KUM56270.1 - 0.03 13.5 0.1 0.034 13.3 0.1 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme RmlD_sub_bind PF04321.12 KUM56270.1 - 0.047 12.5 0.0 0.063 12.1 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain YjeF_N PF03853.10 KUM56270.1 - 0.11 12.1 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 YjeF-related protein N-terminus NAD_binding_4 PF07993.7 KUM56270.1 - 0.11 11.4 0.1 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Epimerase PF01370.16 KUM56270.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family PCNA_C PF02747.10 KUM56271.1 - 0.072 13.0 0.0 0.091 12.6 0.0 1.2 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, C-terminal domain MFS_1 PF07690.11 KUM56272.1 - 5.3e-13 48.4 21.7 5.3e-13 48.4 15.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2196 PF09962.4 KUM56273.1 - 1.6e-22 79.0 0.2 2.9e-22 78.2 0.2 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) Glyco_hydro_31 PF01055.21 KUM56274.1 - 1.2e-48 166.1 8.9 1.6e-48 165.6 6.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 UPRTase PF14681.1 KUM56275.1 - 3.4e-36 124.3 0.0 6.5e-36 123.4 0.0 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase HAD PF12710.2 KUM56275.1 - 0.0061 16.7 0.0 0.014 15.5 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KUM56275.1 - 0.0089 16.4 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_33 PF13671.1 KUM56275.1 - 0.087 12.7 0.0 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Glyco_hydro_92 PF07971.7 KUM56276.1 - 7.9e-148 493.2 4.2 1e-147 492.8 2.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 DUF3015 PF11220.3 KUM56276.1 - 0.11 12.1 0.1 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) AA_permease_2 PF13520.1 KUM56277.1 - 1.7e-73 247.6 36.7 2.1e-73 247.3 25.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM56277.1 - 1.3e-19 69.9 33.1 1.7e-19 69.5 22.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3092 PF11289.3 KUM56277.1 - 0.011 14.9 2.5 0.024 13.8 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3092) HNH_2 PF13391.1 KUM56278.1 - 0.0087 15.8 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease zf-RING_2 PF13639.1 KUM56279.1 - 4e-08 32.9 10.4 1.7e-07 30.9 2.9 2.5 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KUM56279.1 - 1.1e-07 31.7 5.6 3.8e-07 30.1 1.5 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KUM56279.1 - 0.00016 21.4 2.4 0.00016 21.4 1.7 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KUM56279.1 - 0.0023 17.8 4.0 0.0023 17.8 2.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 KUM56279.1 - 0.0041 17.0 4.6 0.012 15.6 3.2 1.8 1 0 0 1 1 1 1 RING-like domain Fib_alpha PF08702.5 KUM56279.1 - 0.0057 16.7 0.1 0.012 15.7 0.1 1.5 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family PHD PF00628.24 KUM56279.1 - 0.02 14.5 7.7 0.024 14.3 3.7 2.2 2 0 0 2 2 2 0 PHD-finger FANCL_C PF11793.3 KUM56279.1 - 0.042 13.8 7.4 0.19 11.7 2.5 2.7 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.2 KUM56279.1 - 0.35 10.9 11.1 0.033 14.2 3.5 2.2 2 0 0 2 2 2 0 RING-variant domain zf-RING_4 PF14570.1 KUM56279.1 - 0.86 9.2 8.3 0.038 13.5 1.7 1.8 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 KUM56279.1 - 1.8 8.3 11.2 0.036 13.7 2.6 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Striatin PF08232.7 KUM56279.1 - 2.6 8.3 6.6 0.2 11.9 0.2 2.3 2 1 0 2 2 2 0 Striatin family zf-C3HC4_4 PF15227.1 KUM56279.1 - 8.4 6.3 10.7 0.32 10.8 3.0 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING GMC_oxred_C PF05199.8 KUM56281.1 - 2.8e-32 112.0 0.0 4.4e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KUM56281.1 - 5.9e-29 101.1 0.0 2.8e-20 72.6 0.0 3.1 3 0 0 3 3 3 3 GMC oxidoreductase DAO PF01266.19 KUM56281.1 - 0.003 16.5 0.1 0.25 10.2 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KUM56281.1 - 0.0031 17.4 0.1 0.011 15.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KUM56281.1 - 0.013 14.3 0.2 0.029 13.2 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 KUM56281.1 - 0.015 15.1 0.0 0.11 12.4 0.0 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KUM56281.1 - 0.11 11.9 0.2 0.22 10.9 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Cyclin PF08613.6 KUM56282.1 - 3.3e-17 63.2 0.0 9.8e-17 61.7 0.0 1.8 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 KUM56282.1 - 0.00013 21.5 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ribosomal_L18e PF00828.14 KUM56283.1 - 1.4e-14 54.6 0.1 2.7e-14 53.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Rick_17kDa_Anti PF05433.10 KUM56284.1 - 2.1e-06 27.2 3.9 3.2e-06 26.6 2.7 1.2 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 KUM56284.1 - 0.0034 16.9 1.6 0.006 16.2 1.1 1.3 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_OmpA PF13436.1 KUM56284.1 - 0.01 15.5 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Zip PF02535.17 KUM56284.1 - 0.027 13.4 16.3 0.033 13.2 11.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TraT PF05818.7 KUM56284.1 - 0.055 12.8 0.1 0.091 12.1 0.1 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Gly-zipper_YMGG PF13441.1 KUM56284.1 - 4.2 6.9 8.4 15 5.2 5.9 1.7 1 1 0 1 1 1 0 YMGG-like Gly-zipper PAT1 PF09770.4 KUM56284.1 - 4.4 5.4 14.7 6.7 4.8 10.2 1.3 1 1 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pkinase PF00069.20 KUM56285.1 - 3.9e-49 167.1 0.0 5.3e-49 166.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM56285.1 - 3.5e-27 95.1 0.0 1.7e-26 92.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase SH3_1 PF00018.23 KUM56286.1 - 8.4e-07 28.2 0.0 1.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KUM56286.1 - 0.00037 20.0 0.0 0.0007 19.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Phage_ASH PF10554.4 KUM56287.1 - 0.13 12.5 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Ash protein family Glyco_hydro_20 PF00728.17 KUM56288.1 - 4.8e-35 121.3 2.5 2.3e-34 119.1 1.7 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.10 KUM56288.1 - 1.5e-08 35.2 0.0 4.1e-08 33.7 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Cu_amine_oxid PF01179.15 KUM56289.1 - 5.3e-106 354.8 0.3 7.1e-106 354.3 0.2 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 KUM56289.1 - 2.8e-26 91.2 0.7 1.2e-25 89.2 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 KUM56289.1 - 0.0043 17.1 0.1 0.026 14.5 0.0 2.2 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain 2OG-FeII_Oxy PF03171.15 KUM56290.1 - 3.3e-05 24.0 0.4 8.9e-05 22.7 0.0 1.9 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KUM56290.1 - 0.023 15.1 0.3 0.074 13.5 0.0 2.0 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily TauD PF02668.11 KUM56290.1 - 0.061 12.9 0.3 0.091 12.4 0.2 1.4 1 1 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family DUF4531 PF15041.1 KUM56290.1 - 0.079 12.7 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4531) Aldo_ket_red PF00248.16 KUM56291.1 - 7.7e-53 179.1 0.0 9.3e-53 178.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family 2OG-FeII_Oxy_3 PF13640.1 KUM56292.1 - 0.00019 21.8 0.0 0.0008 19.8 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KUM56292.1 - 0.0011 19.2 0.0 0.0077 16.5 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peptidase_M3 PF01432.15 KUM56293.1 - 3.8e-69 233.9 0.1 6.1e-69 233.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 DUF3201 PF11447.3 KUM56293.1 - 0.032 13.6 0.0 0.6 9.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3201) Peptidase_M3 PF01432.15 KUM56294.1 - 2.9e-30 105.7 0.0 3.3e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M3 PS_Dcarbxylase PF02666.10 KUM56295.1 - 1.4e-46 158.3 0.0 1.7e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Muskelin_N PF06588.6 KUM56298.1 - 0.15 11.7 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Muskelin N-terminus tRNA-synt_1c PF00749.16 KUM56299.1 - 3.6e-98 328.0 0.0 5.2e-98 327.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KUM56299.1 - 6.2e-37 126.9 0.1 1.2e-36 126.0 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 KUM56299.1 - 1.6e-07 31.7 0.1 4.4e-07 30.2 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KUM56299.1 - 0.0076 16.2 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 KUM56299.1 - 0.034 13.2 0.3 0.086 11.9 0.1 1.5 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain Ribosomal_L1 PF00687.16 KUM56300.1 - 2.3e-30 105.5 0.0 2.7e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family COG2 PF06148.6 KUM56301.1 - 2.7e-36 124.3 1.7 5.2e-36 123.4 1.2 1.4 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 KUM56301.1 - 2.7e-06 27.1 1.6 9.9e-06 25.3 0.1 2.4 1 1 1 2 2 2 1 Vps51/Vps67 COG5 PF10392.4 KUM56301.1 - 0.00014 21.8 1.2 0.0013 18.6 0.2 2.2 2 0 0 2 2 2 1 Golgi transport complex subunit 5 DUF2450 PF10475.4 KUM56301.1 - 0.022 13.6 0.1 0.032 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Bul1_C PF04426.7 KUM56301.1 - 0.045 12.9 0.1 0.13 11.3 0.0 1.8 1 1 1 2 2 2 0 Bul1 C terminus Prominin PF05478.6 KUM56301.1 - 0.074 10.5 0.0 0.099 10.1 0.0 1.1 1 0 0 1 1 1 0 Prominin IncA PF04156.9 KUM56301.1 - 0.15 11.6 7.1 0.14 11.7 3.9 1.6 1 1 0 1 1 1 0 IncA protein Atg14 PF10186.4 KUM56301.1 - 0.17 10.8 3.1 0.27 10.1 2.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Sec34 PF04136.10 KUM56301.1 - 0.19 11.4 1.1 0.84 9.3 0.1 2.0 1 1 1 2 2 2 0 Sec34-like family Spc7 PF08317.6 KUM56301.1 - 0.26 9.9 3.7 0.54 8.8 2.6 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein FlaC_arch PF05377.6 KUM56301.1 - 0.51 10.2 6.3 16 5.5 0.1 3.7 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Cwf_Cwc_15 PF04889.7 KUM56301.1 - 2.1 7.9 10.0 0.52 9.9 4.9 1.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Thioredoxin PF00085.15 KUM56304.1 - 4.7e-27 93.6 0.1 5.3e-27 93.5 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KUM56304.1 - 4.6e-06 26.7 1.5 3e-05 24.2 1.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KUM56304.1 - 1.5e-05 24.9 0.1 2.9e-05 24.1 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like Phosducin PF02114.11 KUM56304.1 - 5.3e-05 22.0 0.0 5.7e-05 21.9 0.0 1.0 1 0 0 1 1 1 1 Phosducin Thioredoxin_7 PF13899.1 KUM56304.1 - 0.00015 21.6 0.2 0.00022 21.1 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 KUM56304.1 - 0.00082 19.0 0.1 0.0013 18.4 0.1 1.3 1 1 0 1 1 1 1 AhpC/TSA family TraF PF13728.1 KUM56304.1 - 0.002 17.6 0.0 0.0025 17.3 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.1 KUM56304.1 - 0.0026 17.3 0.0 0.0031 17.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.19 KUM56304.1 - 0.1 12.5 0.5 0.16 11.9 0.3 1.5 1 1 0 1 1 1 0 Glutaredoxin RRM_1 PF00076.17 KUM56305.1 - 6.3e-25 86.6 0.1 7.4e-25 86.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM56305.1 - 7.4e-19 67.5 0.0 8.4e-19 67.3 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM56305.1 - 2.1e-11 43.5 0.0 2.5e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KUM56305.1 - 0.0067 16.1 0.1 0.015 15.0 0.1 1.6 1 1 0 1 1 1 1 Limkain b1 RRM_3 PF08777.6 KUM56305.1 - 0.032 14.0 0.1 0.047 13.5 0.1 1.3 1 1 0 1 1 1 0 RNA binding motif DUF4078 PF13300.1 KUM56305.1 - 0.063 13.4 0.9 0.083 13.0 0.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4078) Cu-oxidase_3 PF07732.10 KUM56306.1 - 2.1e-36 124.2 1.0 2.7e-35 120.6 0.1 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KUM56306.1 - 4.8e-28 97.3 6.8 1.7e-23 82.6 1.1 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KUM56306.1 - 7.4e-16 58.4 0.0 1.2e-14 54.5 0.0 2.8 3 1 0 3 3 3 1 Multicopper oxidase Homeobox_KN PF05920.6 KUM56307.1 - 1.1e-14 53.8 2.3 2.6e-14 52.6 1.6 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KUM56307.1 - 1.6e-06 27.5 0.1 3.7e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 Homeobox domain HTH_Tnp_Tc5 PF03221.11 KUM56307.1 - 0.00047 19.9 0.0 0.0013 18.4 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain zf-C2H2 PF00096.21 KUM56307.1 - 0.001 19.3 18.7 0.038 14.3 0.8 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KUM56307.1 - 0.014 15.6 1.1 0.014 15.6 0.8 5.2 5 2 0 5 5 5 0 C2H2-type zinc finger GFA PF04828.9 KUM56308.1 - 5.5e-22 77.5 0.1 8.3e-22 76.9 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF4220 PF13968.1 KUM56308.1 - 0.039 13.0 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Auto_anti-p27 PF06677.7 KUM56308.1 - 0.094 12.4 0.1 0.094 12.4 0.1 1.8 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) RNA_POL_M_15KD PF02150.11 KUM56308.1 - 0.11 12.1 0.1 0.11 12.1 0.1 1.7 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit DUF3602 PF12223.3 KUM56309.1 - 1 9.7 7.5 10 6.6 0.0 3.8 3 2 0 3 3 3 0 Protein of unknown function (DUF3602) Pro-kuma_activ PF09286.6 KUM56310.1 - 7.7e-51 171.8 0.1 1.3e-49 167.8 0.0 2.4 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KUM56310.1 - 6.3e-05 22.2 0.2 9.9e-05 21.6 0.1 1.3 1 0 0 1 1 1 1 Subtilase family INSIG PF07281.7 KUM56313.1 - 1.4e-82 275.7 1.7 1.7e-82 275.4 1.2 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) AICARFT_IMPCHas PF01808.13 KUM56315.1 - 6.4e-108 360.5 0.0 8.8e-108 360.0 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 KUM56315.1 - 7.2e-25 86.7 0.0 1.6e-24 85.6 0.0 1.7 1 0 0 1 1 1 1 MGS-like domain FMN_dh PF01070.13 KUM56317.1 - 9.7e-105 350.3 0.0 1.2e-104 349.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KUM56317.1 - 1.6e-06 27.3 0.1 2.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KUM56317.1 - 3.7e-06 26.0 0.2 0.00083 18.3 0.0 2.8 3 0 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KUM56317.1 - 0.01 15.0 0.1 0.021 13.9 0.1 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.16 KUM56317.1 - 0.017 14.3 0.0 0.037 13.3 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF1824 PF08854.5 KUM56317.1 - 0.098 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1824) SNF2_N PF00176.18 KUM56318.1 - 6.5e-43 146.6 0.2 1.1e-42 145.8 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KUM56318.1 - 8.5e-13 47.9 0.0 3.5e-12 46.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KUM56318.1 - 1.1e-06 28.6 0.0 2.6e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 KUM56318.1 - 0.029 13.5 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.1 KUM56318.1 - 0.09 12.9 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain GSH_synth_ATP PF03917.12 KUM56319.1 - 1.1e-99 333.4 0.0 1.4e-99 333.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 KUM56319.1 - 5.3e-30 103.5 0.0 8.6e-30 102.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Ank_2 PF12796.2 KUM56320.1 - 5.3e-06 26.6 2.0 0.00039 20.6 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KUM56320.1 - 0.00037 20.1 0.4 0.0021 17.7 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat F-box-like PF12937.2 KUM56320.1 - 0.035 13.8 0.0 0.081 12.6 0.0 1.6 1 0 0 1 1 1 0 F-box-like Bestrophin PF01062.16 KUM56321.1 - 8.6e-50 169.3 2.1 1.6e-48 165.1 1.5 2.0 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF876 PF05936.7 KUM56321.1 - 0.13 10.7 0.0 0.17 10.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF876) adh_short PF00106.20 KUM56322.1 - 2.6e-13 50.2 0.4 4.1e-13 49.5 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM56322.1 - 1.1e-07 31.7 0.3 1.6e-07 31.1 0.2 1.3 1 0 0 1 1 1 1 KR domain Fungal_trans PF04082.13 KUM56323.1 - 2e-21 76.0 0.3 5.8e-21 74.5 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM56323.1 - 7.2e-09 35.4 10.7 1.6e-08 34.3 7.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4306 PF14154.1 KUM56323.1 - 0.2 11.6 0.6 0.45 10.5 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) Metallophos_2 PF12850.2 KUM56324.1 - 4.9e-10 39.4 0.0 1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KUM56324.1 - 1.9e-07 30.6 0.3 3.1e-06 26.7 0.2 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase AMP-binding PF00501.23 KUM56327.1 - 1.3e-71 241.2 0.0 1.7e-71 240.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KUM56327.1 - 0.003 18.4 0.0 0.0073 17.2 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FAD_binding_7 PF03441.9 KUM56328.1 - 2.3e-99 332.1 0.1 4.1e-99 331.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KUM56328.1 - 5.9e-42 143.2 0.2 9.7e-42 142.5 0.1 1.3 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.21 KUM56328.1 - 0.098 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Universal stress protein family Peptidase_M3 PF01432.15 KUM56331.1 - 1.9e-101 340.4 0.0 2.5e-101 339.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 2OG-FeII_Oxy PF03171.15 KUM56332.1 - 8.4e-05 22.8 0.1 0.00018 21.7 0.1 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KUM56332.1 - 0.00011 22.6 0.1 0.0004 20.8 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily CHAP PF05257.11 KUM56332.1 - 0.075 12.6 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 CHAP domain Pkinase PF00069.20 KUM56333.1 - 5.8e-07 28.9 0.0 2.8e-06 26.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM56333.1 - 0.018 14.1 0.0 0.036 13.1 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase DUF2841 PF11001.3 KUM56336.1 - 2.4e-05 24.2 0.0 3.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) TCP PF03634.8 KUM56338.1 - 0.11 12.9 0.0 0.13 12.5 0.0 1.3 1 1 0 1 1 1 0 TCP family transcription factor Tyrosinase PF00264.15 KUM56340.1 - 4.2e-48 164.4 0.3 5.8e-48 163.9 0.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Peptidase_M20 PF01546.23 KUM56342.1 - 2.8e-20 72.6 0.0 3.6e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KUM56342.1 - 1.2e-17 63.7 0.0 2.1e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KUM56342.1 - 0.026 14.2 0.0 0.3 10.7 0.0 2.4 2 1 0 2 2 2 0 Peptidase family M28 AA_permease_2 PF13520.1 KUM56343.1 - 4.3e-41 140.8 47.7 5.4e-41 140.5 33.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM56343.1 - 2.5e-20 72.2 43.4 3.5e-20 71.8 30.1 1.1 1 0 0 1 1 1 1 Amino acid permease Meth_synt_2 PF01717.13 KUM56344.1 - 8.7e-138 458.7 0.0 1e-133 445.3 0.0 2.4 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KUM56344.1 - 3.3e-122 407.6 0.0 6.1e-111 370.6 0.0 3.2 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Metallophos PF00149.23 KUM56345.1 - 0.00017 21.0 0.9 0.0022 17.4 0.6 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KUM56345.1 - 0.023 14.5 0.4 0.055 13.3 0.2 1.7 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain BTB PF00651.26 KUM56346.1 - 2.2e-08 34.0 0.2 7e-08 32.4 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain zf-C4pol PF14260.1 KUM56346.1 - 0.033 14.1 1.1 0.086 12.8 0.1 2.0 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta G-patch PF01585.18 KUM56347.1 - 1.9e-09 37.1 1.5 4.3e-09 36.0 0.7 1.8 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 KUM56347.1 - 0.00018 21.2 0.2 0.00061 19.5 0.1 1.9 1 0 0 1 1 1 1 DExH-box splicing factor binding site RRM_5 PF13893.1 KUM56347.1 - 0.0092 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KUM56347.1 - 0.046 13.3 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HhH-GPD PF00730.20 KUM56348.1 - 2.3e-14 53.5 0.0 4.9e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF43 PF01861.11 KUM56348.1 - 0.15 11.0 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF43 UCR_14kD PF02271.11 KUM56349.1 - 1.6e-45 153.1 0.1 1.8e-45 152.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Ferritin PF00210.19 KUM56349.1 - 0.044 13.5 0.0 0.12 12.1 0.0 1.7 1 1 0 1 1 1 0 Ferritin-like domain DUF4211 PF13926.1 KUM56349.1 - 0.11 11.9 0.1 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) Mito_carr PF00153.22 KUM56350.1 - 4.4e-68 225.0 0.1 1.8e-22 78.8 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein NAD_binding_1 PF00175.16 KUM56351.1 - 1.2e-13 51.5 0.0 3.7e-13 49.9 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Globin PF00042.17 KUM56351.1 - 1.1e-09 38.6 0.1 2.9e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Globin FAD_binding_6 PF00970.19 KUM56351.1 - 3.3e-09 36.7 0.0 5.6e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KUM56351.1 - 1.2e-05 25.3 0.0 0.00022 21.1 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Protoglobin PF11563.3 KUM56351.1 - 2.7e-05 23.8 0.2 5.1e-05 22.9 0.2 1.4 1 0 0 1 1 1 1 Protoglobin Cupin_2 PF07883.6 KUM56355.1 - 9.9e-09 34.5 0.0 1.4e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 KUM56355.1 - 0.043 13.2 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_1 PF00190.17 KUM56355.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Cupin Peptidase_S15 PF02129.13 KUM56356.1 - 7.3e-41 140.3 0.5 1e-40 139.8 0.4 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 KUM56356.1 - 8.2e-40 137.0 0.2 1.2e-39 136.4 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_5 PF12695.2 KUM56356.1 - 1.3e-05 24.9 0.0 2.2e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KUM56356.1 - 7.7e-05 22.6 0.1 0.00012 22.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KUM56356.1 - 0.02 14.7 0.0 0.05 13.4 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase LigB PF02900.13 KUM56358.1 - 8.9e-19 67.5 0.0 1.1e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase MFS_1 PF07690.11 KUM56360.1 - 3.7e-38 131.1 24.3 3.7e-38 131.1 16.9 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM56360.1 - 3.3e-13 49.0 19.1 7e-13 47.9 13.2 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KUM56360.1 - 3e-09 35.6 5.8 6.4e-09 34.5 4.0 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3169 PF11368.3 KUM56360.1 - 0.0019 17.4 7.1 0.07 12.3 0.2 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF3169) OATP PF03137.15 KUM56360.1 - 0.0044 15.1 2.0 0.015 13.3 1.4 1.9 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Aldedh PF00171.17 KUM56361.1 - 5.1e-17 61.3 0.0 6.3e-10 37.9 0.0 2.9 3 0 0 3 3 3 3 Aldehyde dehydrogenase family FAD_binding_3 PF01494.14 KUM56362.1 - 4.5e-23 81.8 0.0 7.9e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KUM56362.1 - 1e-07 31.8 0.2 2.7e-07 30.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ADC PF06314.6 KUM56362.1 - 1.1e-07 31.5 0.0 1.7e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) FAD_binding_2 PF00890.19 KUM56362.1 - 1.3e-05 24.2 0.4 2.4e-05 23.3 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KUM56362.1 - 1.4e-05 24.1 0.0 2.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KUM56362.1 - 5.2e-05 23.2 0.0 8.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KUM56362.1 - 0.00056 20.0 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KUM56362.1 - 0.0036 16.0 0.1 0.0059 15.2 0.1 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox PF00070.22 KUM56362.1 - 0.0036 17.6 0.6 0.02 15.2 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KUM56362.1 - 0.0063 15.4 0.3 0.01 14.7 0.2 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 KUM56362.1 - 0.0067 15.5 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.16 KUM56362.1 - 0.0085 15.6 0.1 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 KUM56362.1 - 0.014 13.9 0.1 0.026 12.9 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein DUF1344 PF07076.6 KUM56362.1 - 0.058 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) NAD_binding_9 PF13454.1 KUM56362.1 - 0.065 13.0 0.7 0.23 11.2 0.5 2.1 1 1 0 1 1 1 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 KUM56362.1 - 0.086 11.9 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase SE PF08491.5 KUM56362.1 - 0.24 10.1 0.0 0.48 9.2 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase Mur_ligase_C PF02875.16 KUM56364.1 - 0.0094 15.9 0.0 0.047 13.7 0.0 2.0 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain DUF3357 PF11837.3 KUM56365.1 - 0.01 15.6 6.4 1.1 9.1 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) DUF805 PF05656.9 KUM56365.1 - 0.064 13.0 1.5 0.34 10.7 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF805) TraS PF10624.4 KUM56365.1 - 0.09 12.3 0.2 8.9 5.8 0.0 2.3 2 0 0 2 2 2 0 Plasmid conjugative transfer entry exclusion protein TraS TMEM192 PF14802.1 KUM56365.1 - 1.1 8.0 7.5 0.68 8.7 0.9 2.2 1 1 1 2 2 2 0 TMEM192 family rve PF00665.21 KUM56366.1 - 0.0013 18.7 0.0 0.002 18.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Methyltransf_23 PF13489.1 KUM56368.1 - 2.6e-16 59.7 0.3 6.2e-16 58.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM56368.1 - 5.3e-08 33.4 0.0 6.4e-07 29.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM56368.1 - 0.0009 18.8 0.0 0.0085 15.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM56368.1 - 0.0041 17.5 0.0 0.06 13.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KUM56368.1 - 0.0053 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KUM56368.1 - 0.0064 15.5 0.0 0.015 14.3 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.7 KUM56368.1 - 0.016 15.7 0.0 0.049 14.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 KUM56368.1 - 0.052 12.8 0.0 0.079 12.2 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain HhH-GPD PF00730.20 KUM56371.1 - 2.6e-09 37.3 0.0 5.2e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein RRM_1 PF00076.17 KUM56372.1 - 5.6e-27 93.1 0.6 2.4e-11 43.0 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM56372.1 - 1.8e-20 72.6 0.1 3.1e-05 23.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM56372.1 - 1.3e-15 56.9 0.0 1.7e-08 34.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VRR_NUC PF08774.6 KUM56373.1 - 1e-17 63.9 0.0 4.6e-17 61.8 0.0 2.2 2 0 0 2 2 2 1 VRR-NUC domain Ribosomal_S13_N PF08069.7 KUM56374.1 - 7.1e-28 96.2 0.0 1.5e-27 95.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 KUM56374.1 - 1.2e-21 76.2 0.0 2.1e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 KUM56374.1 - 0.027 14.1 0.1 0.1 12.2 0.0 1.9 2 0 0 2 2 2 0 'Paired box' domain Dpy-30 PF05186.8 KUM56376.1 - 4.3e-15 54.8 0.0 5.8e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif ketoacyl-synt PF00109.21 KUM56377.1 - 8.5e-76 254.7 0.0 1.5e-75 253.9 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KUM56377.1 - 2.5e-48 165.0 0.1 4.2e-48 164.3 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KUM56377.1 - 3.3e-33 114.0 0.1 8.9e-33 112.6 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 KUM56377.1 - 4.5e-31 108.8 0.0 1.9e-30 106.7 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain PS-DH PF14765.1 KUM56377.1 - 1.5e-19 70.3 0.0 2.9e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 KUM56377.1 - 1.6e-15 57.0 10.0 1.9e-07 31.2 0.9 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 KUM56377.1 - 9.5e-07 28.9 0.0 0.00023 21.1 0.0 3.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM56377.1 - 0.00036 20.2 0.1 1.2 8.9 0.0 3.0 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 KUM56377.1 - 0.00038 19.5 0.0 0.00077 18.5 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain FMO-like PF00743.14 KUM56378.1 - 2.8e-62 210.6 0.0 3.9e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KUM56378.1 - 6.7e-16 58.9 0.0 3e-15 56.8 0.0 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KUM56378.1 - 2.3e-06 26.7 0.0 1.7e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 KUM56378.1 - 0.03 14.7 0.1 0.085 13.2 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM56378.1 - 0.11 12.3 0.0 20 4.8 0.0 2.8 2 1 0 2 2 2 0 FAD-NAD(P)-binding ELFV_dehydrog PF00208.16 KUM56378.1 - 0.19 11.3 0.0 0.59 9.6 0.0 1.7 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase MFS_1 PF07690.11 KUM56379.1 - 4.3e-42 144.0 49.1 7.7e-41 139.9 35.4 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1381 PF07129.6 KUM56379.1 - 0.055 12.8 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1381) WTF PF03303.8 KUM56379.1 - 0.14 11.5 2.6 0.26 10.6 0.6 2.2 2 0 0 2 2 2 0 WTF protein SPC25 PF06703.6 KUM56379.1 - 8.1 5.9 9.2 22 4.6 0.8 3.2 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) SLAC1 PF03595.12 KUM56382.1 - 3.1e-67 226.5 40.2 3.7e-67 226.3 27.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel MFS_1 PF07690.11 KUM56383.1 - 3.4e-31 108.2 17.4 3.4e-31 108.2 12.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3328 PF11807.3 KUM56383.1 - 0.044 13.4 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) AHS2 PF02626.10 KUM56385.1 - 2.2e-72 243.6 0.0 3.2e-72 243.0 0.0 1.3 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 KUM56385.1 - 5.8e-52 176.0 0.0 1e-51 175.2 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AHS1 PF02682.11 KUM56385.1 - 1.7e-35 122.3 0.0 3.7e-35 121.2 0.0 1.5 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 Biotin_carb_C PF02785.14 KUM56385.1 - 1.7e-33 114.7 0.0 3.5e-33 113.7 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 KUM56385.1 - 4e-11 42.9 0.0 7e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_chain PF00289.17 KUM56385.1 - 9.8e-10 38.5 0.0 2.9e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_lipoyl PF00364.17 KUM56385.1 - 4.2e-09 35.9 1.5 2.5e-07 30.2 0.7 3.3 2 1 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 KUM56385.1 - 0.0022 17.4 0.0 0.0047 16.3 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_5 PF13549.1 KUM56385.1 - 0.024 13.8 0.0 0.057 12.6 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 KUM56385.1 - 0.027 14.1 0.1 0.096 12.3 0.1 1.9 1 0 0 1 1 1 0 Biotin-lipoyl like LamB_YcsF PF03746.11 KUM56386.1 - 5.7e-71 238.4 0.0 7.1e-71 238.1 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family DNA_ligase_A_M PF01068.16 KUM56387.1 - 5.8e-50 169.4 0.2 3.6e-47 160.3 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KUM56387.1 - 4.2e-43 147.2 0.0 7.5e-43 146.3 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KUM56387.1 - 1.7e-18 66.7 0.0 7.1e-18 64.8 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region TACC PF05010.9 KUM56388.1 - 0.0082 15.9 1.0 0.0083 15.9 0.7 1.0 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) Pyr_redox_3 PF13738.1 KUM56390.1 - 4.1e-24 85.7 0.0 6.5e-23 81.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM56390.1 - 2.6e-10 40.1 0.0 7.2e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KUM56390.1 - 6.7e-10 39.1 0.0 9.5e-07 28.8 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KUM56390.1 - 1.6e-08 33.2 0.2 8.9e-08 30.7 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KUM56390.1 - 2.6e-07 29.9 0.0 0.00089 18.2 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KUM56390.1 - 6e-07 29.3 0.1 0.00025 20.8 0.0 2.6 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.19 KUM56390.1 - 1.9e-05 23.7 0.0 0.0011 17.9 0.0 2.8 1 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 KUM56390.1 - 0.00062 18.9 0.0 0.022 13.8 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 KUM56390.1 - 0.0014 19.0 0.0 0.071 13.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KUM56390.1 - 0.004 17.2 0.0 0.69 10.0 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 KUM56390.1 - 0.13 11.0 0.1 0.31 9.8 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain DUF1365 PF07103.6 KUM56391.1 - 1.7e-13 50.2 0.0 5.5e-09 35.4 0.0 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF1365) Epimerase PF01370.16 KUM56392.1 - 0.00024 20.5 0.0 0.00035 20.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KUM56392.1 - 0.0021 18.1 0.0 0.0032 17.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KUM56392.1 - 0.12 12.6 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Chitin_synth_2 PF03142.10 KUM56393.1 - 6.9e-25 87.4 2.2 4.2e-23 81.5 1.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KUM56393.1 - 4.9e-17 62.2 6.2 1.6e-16 60.6 4.3 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KUM56393.1 - 6.6e-15 55.5 0.0 1.1e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KUM56393.1 - 0.091 12.4 0.1 16 5.1 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 La PF05383.12 KUM56394.1 - 2.7e-18 65.5 0.0 4.4e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 KUM56394.1 - 1.3e-08 34.3 0.1 3.7e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM56394.1 - 4.4e-06 26.5 0.0 1e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM56394.1 - 0.0096 15.7 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dabb PF07876.7 KUM56395.1 - 1.5e-17 63.8 0.0 1.6e-17 63.6 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Sulfatase PF00884.18 KUM56396.1 - 7.1e-20 71.3 1.6 1.3e-19 70.4 1.1 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KUM56396.1 - 0.00016 21.1 0.4 0.00029 20.2 0.3 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KUM56396.1 - 0.096 11.0 0.0 0.17 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) HSP70 PF00012.15 KUM56398.1 - 6.7e-160 532.9 2.2 6.7e-160 532.9 1.5 1.6 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 KUM56398.1 - 3.4e-10 39.0 0.0 2.7e-09 36.0 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 KUM56398.1 - 0.00023 20.9 0.2 0.4 10.5 0.0 3.0 2 1 0 2 2 2 2 Cell division protein FtsA p450 PF00067.17 KUM56400.1 - 3.5e-62 210.4 0.0 4.7e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 EPSP_synthase PF00275.15 KUM56401.1 - 4.9e-127 423.8 0.0 1.1e-126 422.6 0.0 1.5 2 0 0 2 2 2 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 KUM56401.1 - 2.6e-95 318.2 0.0 4.5e-95 317.5 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 KUM56401.1 - 1.1e-61 208.4 0.0 1.8e-61 207.6 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 KUM56401.1 - 2.1e-41 141.4 0.0 1.2e-40 138.9 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 KUM56401.1 - 2.9e-23 81.7 0.0 7.1e-23 80.4 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KUM56401.1 - 8.9e-10 38.7 0.0 2.3e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 KUM56401.1 - 1.7e-07 30.8 0.0 5e-07 29.2 0.0 1.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 KUM56401.1 - 4.2e-05 24.3 0.0 0.0002 22.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KUM56401.1 - 0.022 15.0 0.0 0.05 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KUM56401.1 - 0.058 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KUM56401.1 - 0.23 11.0 0.0 0.46 10.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sulfotransfer_3 PF13469.1 KUM56402.1 - 2.2e-08 35.1 1.2 6.6e-08 33.6 0.8 1.8 1 1 0 1 1 1 1 Sulfotransferase family Fungal_trans PF04082.13 KUM56404.1 - 9.4e-16 57.4 5.1 1.9e-15 56.4 3.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM56404.1 - 2.2e-09 37.0 10.8 4.2e-09 36.1 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HHH_8 PF14716.1 KUM56404.1 - 0.79 9.9 2.8 3 8.0 0.1 2.5 1 1 1 2 2 2 0 Helix-hairpin-helix domain ADH_N PF08240.7 KUM56405.1 - 1e-08 34.8 0.0 3.2e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM56405.1 - 1.1e-07 31.4 0.1 2.3e-07 30.4 0.1 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.3 KUM56405.1 - 0.003 17.3 0.1 0.15 11.8 0.0 2.5 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Peptidase_S31 PF05578.7 KUM56405.1 - 0.032 13.4 0.0 0.057 12.6 0.0 1.3 1 0 0 1 1 1 0 Pestivirus NS3 polyprotein peptidase S31 FMO-like PF00743.14 KUM56406.1 - 3.9e-42 144.1 0.0 5.9e-22 77.5 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KUM56406.1 - 2e-16 60.6 0.0 6.2e-16 59.0 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM56406.1 - 3.7e-11 43.0 0.0 1.9e-10 40.7 0.0 2.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KUM56406.1 - 5.1e-10 38.7 0.0 3.4e-06 26.2 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KUM56406.1 - 3.8e-07 30.2 0.0 3.1e-06 27.2 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM56406.1 - 2.2e-06 27.5 0.0 5.8e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KUM56406.1 - 9.1e-06 24.9 0.1 0.0003 19.9 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 KUM56406.1 - 0.0013 17.7 0.1 0.049 12.5 0.0 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KUM56406.1 - 0.0024 18.2 0.1 0.039 14.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KUM56406.1 - 0.0026 16.3 0.0 0.0098 14.3 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein TrkA_N PF02254.13 KUM56406.1 - 0.058 13.3 0.0 0.54 10.2 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain Shikimate_DH PF01488.15 KUM56406.1 - 0.1 12.6 0.0 0.56 10.3 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase LysM PF01476.15 KUM56407.1 - 8e-12 44.8 0.1 7.3e-05 22.5 0.1 2.7 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 KUM56407.1 - 1.5e-05 24.8 4.7 0.00013 21.8 3.2 2.6 1 0 0 1 1 1 1 Chitin recognition protein Peptidase_S8 PF00082.17 KUM56408.1 - 1.4e-44 152.3 15.9 2.1e-44 151.7 11.0 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KUM56408.1 - 2.1e-13 50.6 0.0 3.8e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 KCNQC3-Ank-G_bd PF11956.3 KUM56409.1 - 0.0094 15.9 0.5 0.015 15.3 0.4 1.4 1 0 0 1 1 1 1 Ankyrin-G binding motif of KCNQ2-3 F-box-like PF12937.2 KUM56410.1 - 0.0043 16.7 0.1 0.0088 15.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like Rav1p_C PF12234.3 KUM56413.1 - 2.9e-269 894.5 0.0 3.8e-269 894.2 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 KUM56413.1 - 4.2e-06 26.4 0.6 0.4 10.6 0.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat p450 PF00067.17 KUM56414.1 - 2.2e-59 201.1 0.0 2.7e-59 200.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tir_receptor_C PF07489.6 KUM56415.1 - 0.0062 16.3 1.9 0.0062 16.3 1.3 2.1 2 0 0 2 2 2 1 Translocated intimin receptor (Tir) C-terminus Sfi1 PF08457.5 KUM56416.1 - 2.8e-181 603.8 82.2 2.8e-181 603.8 57.0 2.0 1 1 0 1 1 1 1 Sfi1 spindle body protein Cmc1 PF08583.5 KUM56418.1 - 0.0072 16.0 0.7 0.012 15.3 0.5 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.11 KUM56418.1 - 0.1 12.5 0.9 0.15 12.0 0.6 1.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein FAD_binding_3 PF01494.14 KUM56419.1 - 6.7e-21 74.7 0.2 6.1e-20 71.5 0.2 2.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KUM56419.1 - 2.6e-12 46.3 2.1 1.5e-07 30.7 1.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KUM56419.1 - 1.2e-08 34.2 2.8 2.7e-08 33.0 2.0 1.6 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 KUM56419.1 - 3.1e-08 32.9 0.7 0.013 14.4 0.5 2.9 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 KUM56419.1 - 5.6e-07 29.4 1.4 1.6e-06 28.0 0.9 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KUM56419.1 - 3e-06 26.1 1.2 0.0062 15.2 0.2 3.1 2 1 1 3 3 3 2 Tryptophan halogenase Pyr_redox_2 PF07992.9 KUM56419.1 - 5e-06 26.5 0.8 9e-06 25.7 0.6 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KUM56419.1 - 9.4e-06 24.8 0.1 1.6e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KUM56419.1 - 1.6e-05 23.5 0.4 2.5e-05 22.9 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.16 KUM56419.1 - 7.4e-05 22.3 0.1 0.00013 21.5 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 KUM56419.1 - 7.7e-05 21.9 2.1 0.00013 21.2 1.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KUM56419.1 - 0.00011 21.2 0.2 0.00014 20.8 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 KUM56419.1 - 0.00032 21.0 0.2 0.0022 18.3 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KUM56419.1 - 0.0014 18.7 0.0 0.0046 17.0 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KUM56419.1 - 0.0024 17.0 0.4 0.14 11.2 0.2 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 KUM56419.1 - 0.054 13.2 1.2 1.1 9.0 0.4 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 KUM56419.1 - 0.056 12.8 0.2 0.091 12.1 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 KUM56419.1 - 0.092 12.3 0.3 0.2 11.2 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KUM56419.1 - 0.11 11.8 0.3 0.19 11.1 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AD PF09793.4 KUM56420.1 - 5.8e-25 86.9 0.0 9.5e-25 86.2 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain YodL PF14191.1 KUM56420.1 - 0.11 12.9 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 YodL-like GTP_EFTU PF00009.22 KUM56421.1 - 1.6e-08 34.2 0.0 2.5e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 KUM56421.1 - 0.3 10.6 0.2 2.4 7.6 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein HSP70 PF00012.15 KUM56422.1 - 7.8e-06 24.0 0.0 3.5e-05 21.9 0.0 1.8 1 1 0 1 1 1 1 Hsp70 protein Sua5_yciO_yrdC PF01300.13 KUM56423.1 - 4.2e-17 61.9 0.0 7.7e-17 61.1 0.0 1.4 1 1 0 1 1 1 1 Telomere recombination bZIP_1 PF00170.16 KUM56424.1 - 0.11 12.5 3.9 0.67 9.9 0.1 2.5 1 1 1 2 2 2 0 bZIP transcription factor AA_permease_2 PF13520.1 KUM56425.1 - 5.8e-51 173.3 36.2 7e-51 173.1 25.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM56425.1 - 3.9e-19 68.3 29.5 5e-19 67.9 20.5 1.1 1 0 0 1 1 1 1 Amino acid permease Aconitase PF00330.15 KUM56426.1 - 5.7e-179 595.4 0.0 6.8e-179 595.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KUM56426.1 - 1.2e-43 148.4 0.0 2.2e-43 147.4 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Glycos_transf_4 PF00953.16 KUM56427.1 - 5.1e-31 107.6 11.7 5.1e-31 107.6 8.1 2.2 2 1 0 2 2 2 1 Glycosyl transferase family 4 SecE PF00584.15 KUM56427.1 - 3.8 7.1 10.9 2.2 7.9 0.0 4.1 4 0 0 4 4 4 0 SecE/Sec61-gamma subunits of protein translocation complex WD40 PF00400.27 KUM56428.1 - 4.2e-22 77.1 10.0 1.5e-05 24.6 0.0 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 KUM56428.1 - 0.03 12.4 1.8 0.12 10.4 0.1 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 ADH_zinc_N PF00107.21 KUM56429.1 - 4e-11 42.5 0.0 9.9e-11 41.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM56429.1 - 0.00011 21.9 0.0 0.00022 20.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KUM56429.1 - 0.0011 19.8 0.0 0.0022 18.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MFS_1 PF07690.11 KUM56430.1 - 2e-07 30.0 39.7 2.1e-06 26.6 27.5 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KUM56430.1 - 5.2e-07 29.2 4.9 5.2e-07 29.2 3.4 2.5 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 PUCC PF03209.10 KUM56430.1 - 0.21 10.2 11.9 0.029 13.0 5.0 1.9 2 0 0 2 2 2 0 PUCC protein AA_permease PF00324.16 KUM56431.1 - 4.9e-46 157.0 31.8 1.3e-45 155.6 22.0 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KUM56431.1 - 4.8e-15 55.0 29.9 7.8e-15 54.3 20.7 1.4 1 1 0 1 1 1 1 Amino acid permease p450 PF00067.17 KUM56433.1 - 1.4e-72 244.6 0.0 1.8e-72 244.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pmp3 PF01679.12 KUM56433.1 - 0.63 9.7 4.0 1.7 8.4 2.8 1.6 1 0 0 1 1 1 0 Proteolipid membrane potential modulator PhyH PF05721.8 KUM56434.1 - 4.6e-22 79.1 0.0 5.8e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AMP-binding PF00501.23 KUM56435.1 - 5.8e-155 515.7 0.3 1.9e-78 263.7 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KUM56435.1 - 1.8e-69 233.9 0.0 2.9e-50 170.8 0.0 2.4 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KUM56435.1 - 1.4e-23 82.9 0.7 1.8e-12 47.3 0.0 3.8 3 0 0 3 3 3 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 KUM56435.1 - 2.8e-21 75.6 0.5 8e-21 74.1 0.3 1.9 1 0 0 1 1 1 1 HxxPF-repeated domain AMP-binding_C PF13193.1 KUM56435.1 - 3.8e-07 30.9 0.6 0.0088 16.9 0.0 3.5 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Methyltransf_26 PF13659.1 KUM56435.1 - 2.5e-06 27.4 1.3 1.1e-05 25.4 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM56435.1 - 0.00017 21.2 0.0 0.00047 19.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM56435.1 - 0.0004 20.9 0.0 0.0012 19.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM56435.1 - 0.0016 18.8 0.0 0.0048 17.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM56435.1 - 0.0019 18.5 0.0 0.0073 16.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM56435.1 - 0.02 14.6 0.0 0.049 13.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 KUM56435.1 - 0.25 10.7 0.0 0.51 9.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Transferase PF02458.10 KUM56435.1 - 0.27 9.6 0.0 11 4.3 0.0 3.0 3 0 0 3 3 3 0 Transferase family adh_short PF00106.20 KUM56436.1 - 2.8e-28 98.9 0.1 4e-28 98.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM56436.1 - 9.4e-26 91.0 0.2 1.1e-25 90.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM56436.1 - 2.2e-12 47.0 0.1 6.7e-12 45.4 0.1 1.6 2 0 0 2 2 2 1 KR domain Ribosomal_L17 PF01196.14 KUM56436.1 - 0.00089 19.7 0.0 0.73 10.4 0.0 2.4 2 0 0 2 2 2 2 Ribosomal protein L17 Epimerase PF01370.16 KUM56436.1 - 0.0081 15.6 0.4 0.14 11.5 0.3 2.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KUM56436.1 - 0.013 15.3 0.3 0.043 13.6 0.2 1.9 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1712 PF08217.6 KUM56437.1 - 5.2e-14 51.4 0.0 6.3e-12 44.5 0.0 2.3 2 1 0 2 2 2 2 Fungal domain of unknown function (DUF1712) Ima1_N PF09779.4 KUM56438.1 - 9.7e-39 132.8 2.4 2.6e-38 131.4 1.7 1.8 1 0 0 1 1 1 1 Ima1 N-terminal domain Alg14 PF08660.6 KUM56439.1 - 9.7e-53 178.6 0.0 1.4e-52 178.1 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Formyl_trans_N PF00551.14 KUM56440.1 - 6e-23 81.3 0.0 1.3e-22 80.2 0.0 1.4 1 1 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 KUM56440.1 - 0.00089 19.3 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Chorismate_synt PF01264.16 KUM56441.1 - 1.1e-64 218.0 0.0 1.3e-64 217.8 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase BPL_LplA_LipB PF03099.14 KUM56442.1 - 6.5e-16 58.4 0.0 1.6e-15 57.2 0.0 1.7 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family DUF2264 PF10022.4 KUM56443.1 - 3e-134 447.2 0.0 3.6e-134 446.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Sugar_tr PF00083.19 KUM56444.1 - 9.7e-115 383.6 27.8 1.1e-114 383.4 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM56444.1 - 5.4e-16 58.2 36.3 5.4e-16 58.2 25.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidohydro_3 PF07969.6 KUM56445.1 - 9.1e-50 170.0 0.8 1e-49 169.8 0.6 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 KUM56445.1 - 1.1e-09 38.4 0.2 0.00055 19.6 0.0 2.8 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KUM56445.1 - 1.6e-08 34.2 0.8 6.4e-08 32.3 0.0 2.4 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_4 PF13147.1 KUM56445.1 - 7.6e-05 22.8 4.8 0.00026 21.1 0.0 3.1 3 2 0 3 3 3 1 Amidohydrolase DUF1445 PF07286.7 KUM56446.1 - 3.2e-35 120.8 0.0 3.6e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) Myb_DNA-binding PF00249.26 KUM56447.1 - 3.5e-10 39.7 0.0 1e-07 31.9 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain MFS_1 PF07690.11 KUM56448.1 - 2.2e-41 141.7 23.8 2.8e-41 141.3 16.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 KUM56449.1 - 2.9e-10 39.4 0.0 8.8e-10 37.8 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Cation_efflux PF01545.16 KUM56450.1 - 6e-34 117.4 8.3 7.1e-34 117.1 5.8 1.0 1 0 0 1 1 1 1 Cation efflux family DUF4131 PF13567.1 KUM56450.1 - 0.04 13.3 0.9 0.22 10.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) AgrD PF05931.6 KUM56450.1 - 0.14 11.8 0.1 0.41 10.2 0.1 1.8 1 0 0 1 1 1 0 Staphylococcal AgrD protein DUF1673 PF07895.6 KUM56450.1 - 3.2 7.2 6.9 0.82 9.1 2.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) p450 PF00067.17 KUM56451.1 - 1.1e-62 212.1 0.0 1.4e-62 211.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SOG2 PF10428.4 KUM56452.1 - 0.013 14.1 5.5 0.02 13.5 3.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein FAM104 PF15434.1 KUM56452.1 - 0.62 10.2 4.2 1.1 9.5 2.9 1.4 1 0 0 1 1 1 0 Family 104 Dicty_REP PF05086.7 KUM56452.1 - 1.6 6.4 4.3 2.1 5.9 3.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sugar_tr PF00083.19 KUM56453.1 - 3.3e-78 263.2 23.4 4.2e-78 262.9 16.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM56453.1 - 1e-15 57.3 49.6 2.8e-14 52.5 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CBF PF03914.12 KUM56455.1 - 1.1e-47 161.5 0.0 4.6e-47 159.5 0.0 2.2 1 0 0 1 1 1 1 CBF/Mak21 family Prok-E2_C PF14459.1 KUM56455.1 - 0.063 13.3 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family C Acetyltransf_1 PF00583.19 KUM56456.1 - 2.4e-11 43.4 0.1 5.5e-11 42.3 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KUM56456.1 - 1.8e-10 40.8 0.0 3.5e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KUM56456.1 - 6.7e-05 22.9 0.0 0.00014 21.9 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KUM56456.1 - 0.0024 17.7 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KUM56456.1 - 0.027 14.3 0.0 0.081 12.8 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 KUM56456.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_transf_22 PF03901.12 KUM56457.1 - 4.2e-80 269.8 16.2 5.1e-80 269.5 11.2 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family HrpB1_HrpK PF09613.5 KUM56457.1 - 0.013 14.9 0.3 0.024 14.1 0.2 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) ArfGap PF01412.13 KUM56458.1 - 1.1e-34 118.6 0.1 1.1e-34 118.6 0.1 1.7 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Aminotran_3 PF00202.16 KUM56459.1 - 4.6e-105 351.2 0.0 5.7e-105 350.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KUM56459.1 - 0.0026 16.7 0.0 0.0036 16.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KUM56459.1 - 0.042 12.9 0.0 0.083 12.0 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase PITH PF06201.8 KUM56460.1 - 8.6e-40 135.9 0.0 1.3e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 KUM56460.1 - 5.9e-28 96.5 0.1 1e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KUM56460.1 - 1.1e-07 32.0 0.1 4.2e-07 30.1 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KUM56460.1 - 1.7e-07 31.2 0.0 0.00026 21.0 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.1 KUM56460.1 - 0.0006 19.3 0.0 0.00095 18.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 KUM56460.1 - 0.00071 19.2 0.0 0.46 10.1 0.0 2.4 1 1 1 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.1 KUM56460.1 - 0.00073 19.5 0.0 0.0017 18.3 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 KUM56460.1 - 0.0034 16.9 0.2 0.24 10.9 0.0 2.4 1 1 1 2 2 2 1 Redoxin DASH_Spc34 PF08657.5 KUM56460.1 - 0.019 14.6 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 HyaE PF07449.6 KUM56460.1 - 0.031 14.1 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE peroxidase PF00141.18 KUM56461.1 - 1.2e-49 168.8 0.0 1.8e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 Peroxidase zf-CSL PF05207.8 KUM56462.1 - 1.4e-16 59.6 2.3 2.2e-16 59.0 1.6 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 KUM56462.1 - 2.9e-13 49.3 0.2 1.6e-12 46.9 0.2 2.0 1 1 0 1 1 1 1 DnaJ domain AA_permease_2 PF13520.1 KUM56463.1 - 1.1e-42 146.1 54.5 1.3e-42 145.8 37.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM56463.1 - 1.3e-18 66.5 48.5 1.8e-18 66.1 33.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1035 PF06281.7 KUM56463.1 - 2.4 7.9 9.8 0.44 10.3 3.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1035) DUF1993 PF09351.5 KUM56464.1 - 6e-46 156.3 0.1 6.9e-46 156.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) PP-binding_2 PF14573.1 KUM56464.1 - 0.14 12.2 0.0 0.41 10.7 0.0 1.6 2 0 0 2 2 2 0 Acyl-carrier DUF4620 PF15399.1 KUM56465.1 - 0.084 13.0 0.1 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4620) DUF2199 PF09965.4 KUM56466.1 - 0.058 13.2 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) Zn_clus PF00172.13 KUM56467.1 - 1.6e-08 34.2 11.1 2.9e-08 33.4 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KUM56467.1 - 9.8e-06 24.3 1.0 1.5e-05 23.7 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_3 PF00933.16 KUM56469.1 - 6.4e-14 51.6 0.0 7.5e-14 51.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Jacalin PF01419.12 KUM56470.1 - 6.7e-07 29.2 0.4 1.5e-06 28.1 0.2 1.6 1 1 0 2 2 2 1 Jacalin-like lectin domain DUF1212 PF06738.7 KUM56471.1 - 2.3e-55 187.0 9.5 4.5e-47 160.0 0.9 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KUM56471.1 - 1.7e-26 92.6 10.1 1.7e-26 92.6 7.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) Abhydrolase_6 PF12697.2 KUM56472.1 - 7.7e-28 97.9 1.8 8.9e-28 97.7 1.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM56472.1 - 3.4e-14 52.8 0.5 3.8e-14 52.6 0.3 1.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM56472.1 - 4.5e-11 42.7 0.0 5.9e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 KUM56472.1 - 0.00033 20.1 0.0 0.00046 19.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.3 KUM56472.1 - 0.00041 20.1 0.0 0.0013 18.5 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase DUF2305 PF10230.4 KUM56472.1 - 0.035 13.5 0.2 0.059 12.7 0.2 1.5 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 KUM56472.1 - 0.047 13.3 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.11 KUM56472.1 - 0.064 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PGAP1 PF07819.8 KUM56472.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein TFIIIC_sub6 PF10419.4 KUM56473.1 - 1.7e-15 56.1 0.0 3.4e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 TFIIIC subunit ELFV_dehydrog PF00208.16 KUM56474.1 - 6e-59 199.5 0.0 9.6e-59 198.8 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 KUM56474.1 - 2e-18 65.3 0.0 4.7e-13 47.5 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase AA_permease PF00324.16 KUM56478.1 - 7.6e-95 318.0 37.0 9.6e-95 317.6 25.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KUM56478.1 - 6.5e-14 51.2 38.8 8.6e-14 50.8 26.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 KUM56478.1 - 0.0068 16.1 2.4 0.0068 16.1 1.7 3.8 3 1 1 4 4 4 2 Domain of unknown function (DUF1772) Cupin_8 PF13621.1 KUM56479.1 - 1.1e-22 80.7 0.0 3.2e-22 79.2 0.0 1.7 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KUM56479.1 - 0.066 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein Pyr_redox_3 PF13738.1 KUM56480.1 - 2.6e-21 76.6 0.4 1.2e-20 74.4 0.3 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KUM56480.1 - 3.4e-07 29.4 0.2 1.2e-05 24.3 0.0 3.1 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 KUM56480.1 - 4.2e-07 28.5 1.0 7.4e-06 24.4 0.7 2.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KUM56480.1 - 0.00018 21.5 0.0 0.00076 19.4 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KUM56480.1 - 0.019 14.0 0.2 1 8.4 0.0 2.7 3 0 0 3 3 3 0 Thi4 family Zn_clus PF00172.13 KUM56481.1 - 3.5e-05 23.6 9.2 5.8e-05 22.9 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KUM56482.1 - 1.4e-20 73.2 0.4 2.6e-20 72.4 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CK_II_beta PF01214.13 KUM56483.1 - 8e-78 260.1 0.0 1.6e-77 259.1 0.0 1.5 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 KUM56483.1 - 0.015 15.9 8.4 0.015 15.9 5.8 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Nucleoplasmin PF03066.10 KUM56483.1 - 4.9 6.6 14.3 0.24 10.8 4.9 2.0 2 0 0 2 2 2 0 Nucleoplasmin BetaGal_dom4_5 PF13364.1 KUM56484.1 - 0.00034 20.8 0.0 0.0022 18.2 0.0 2.1 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain PseudoU_synth_2 PF00849.17 KUM56485.1 - 2.8e-27 95.5 0.0 5.4e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 KUM56485.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 S4 domain Glyco_tran_WecB PF03808.8 KUM56485.1 - 0.023 14.1 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Fringe PF02434.11 KUM56486.1 - 1.9e-05 24.0 3.7 0.00027 20.2 0.1 3.4 3 1 0 3 3 3 1 Fringe-like PAN_4 PF14295.1 KUM56486.1 - 0.19 11.4 2.1 0.27 10.9 0.6 1.8 2 0 0 2 2 2 0 PAN domain Ribosomal_L32e PF01655.13 KUM56487.1 - 1.1e-49 167.0 1.2 1.6e-49 166.5 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L32 GFO_IDH_MocA PF01408.17 KUM56488.1 - 5.2e-19 68.9 0.0 9.4e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KUM56488.1 - 0.003 17.3 0.0 0.0054 16.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Sec2p PF06428.6 KUM56489.1 - 4.3e-09 36.1 12.7 4.3e-09 36.1 8.8 1.9 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p IncA PF04156.9 KUM56489.1 - 0.0006 19.4 6.9 0.0095 15.5 3.1 2.2 2 0 0 2 2 2 1 IncA protein Jnk-SapK_ap_N PF09744.4 KUM56489.1 - 0.03 14.2 8.7 6.3 6.7 6.5 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Fib_alpha PF08702.5 KUM56489.1 - 0.082 13.0 3.1 7.6 6.6 1.4 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF972 PF06156.8 KUM56489.1 - 0.09 13.1 4.6 12 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Phage_GPO PF05929.6 KUM56489.1 - 0.26 10.5 5.4 2 7.6 1.5 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase ECSIT PF06239.6 KUM56489.1 - 0.3 9.9 2.1 0.5 9.1 1.4 1.3 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway bZIP_1 PF00170.16 KUM56489.1 - 0.32 10.9 13.5 0.42 10.5 0.0 3.1 2 1 1 3 3 3 0 bZIP transcription factor AATF-Che1 PF13339.1 KUM56489.1 - 0.42 10.7 8.3 4 7.5 4.0 2.2 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor LMBR1 PF04791.11 KUM56489.1 - 0.86 8.1 2.3 1.2 7.6 1.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein HR1 PF02185.11 KUM56489.1 - 1.2 8.8 12.5 7.4 6.3 5.9 3.0 2 1 0 2 2 2 0 Hr1 repeat Atg14 PF10186.4 KUM56489.1 - 1.3 7.8 11.9 8.1 5.2 5.8 2.3 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ATG16 PF08614.6 KUM56489.1 - 1.9 8.2 19.0 3.3 7.5 1.3 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Vac_Fusion PF02346.11 KUM56489.1 - 2.2 7.7 4.9 7.9 5.9 1.7 2.3 2 0 0 2 2 2 0 Chordopoxvirus fusion protein PROL5-SMR PF15621.1 KUM56489.1 - 2.3 8.6 9.8 4 7.9 6.8 1.4 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family Exonuc_VII_L PF02601.10 KUM56489.1 - 2.3 7.3 10.6 1.9 7.6 5.2 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit Ndc1_Nup PF09531.5 KUM56489.1 - 5.6 5.2 7.4 6.4 5.0 5.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.8 KUM56489.1 - 8.6 6.1 9.1 11 5.7 6.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IpaD PF06511.6 KUM56490.1 - 0.036 13.0 4.9 0.047 12.6 3.4 1.1 1 0 0 1 1 1 0 Invasion plasmid antigen IpaD ATP-synt_E PF05680.7 KUM56490.1 - 2.9 7.8 8.3 5.3 7.0 4.0 2.1 2 0 0 2 2 2 0 ATP synthase E chain Glyco_hydro_35 PF01301.14 KUM56492.1 - 2.6e-45 155.1 0.1 2.9e-45 155.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 MFS_1 PF07690.11 KUM56494.1 - 3.7e-42 144.3 60.2 2e-30 105.7 17.3 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 KUM56494.1 - 4.5e-06 25.1 24.6 8.3e-06 24.2 16.7 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KUM56495.1 - 2.5e-30 105.3 46.8 7.3e-30 103.8 32.4 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_32 PF13679.1 KUM56495.1 - 5.8e-19 68.1 3.5 3.1e-18 65.7 2.4 2.0 1 1 0 1 1 1 1 Methyltransferase domain Sugar_tr PF00083.19 KUM56495.1 - 4.4e-06 25.5 18.0 4.4e-06 25.5 12.5 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter DIT1_PvcA PF05141.7 KUM56496.1 - 1e-85 287.4 0.0 1.5e-85 286.8 0.0 1.3 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein AMP-binding PF00501.23 KUM56496.1 - 2.5e-28 98.6 0.0 4.4e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Transferase PF02458.10 KUM56496.1 - 3e-13 49.0 0.0 3.9e-06 25.5 0.0 3.1 3 0 0 3 3 3 2 Transferase family PP-binding PF00550.20 KUM56496.1 - 9.5e-07 28.9 0.0 2.3e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Proho_convert PF12177.3 KUM56496.1 - 0.065 12.8 0.1 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Prohormone convertase enzyme MFS_1 PF07690.11 KUM56497.1 - 2.5e-22 79.1 62.6 3.8e-14 52.1 27.2 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2976 PF11190.3 KUM56497.1 - 2.3 7.7 15.7 12 5.4 0.0 4.5 5 1 0 5 5 5 0 Protein of unknown function (DUF2976) DUF3723 PF12520.3 KUM56498.1 - 2.1e-188 626.9 0.2 3e-188 626.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) Fzo_mitofusin PF04799.8 KUM56499.1 - 0.11 11.8 0.7 0.2 11.0 0.5 1.4 1 0 0 1 1 1 0 fzo-like conserved region VPS11_C PF12451.3 KUM56499.1 - 0.58 10.0 3.6 15 5.5 0.0 2.7 1 1 1 2 2 2 0 Vacuolar protein sorting protein 11 C terminal DUF3435 PF11917.3 KUM56500.1 - 4.8e-149 496.6 0.0 6.9e-149 496.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-C2H2 PF00096.21 KUM56500.1 - 0.16 12.3 5.4 0.19 12.1 0.3 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type DNA_primase_lrg PF04104.9 KUM56500.1 - 0.31 10.2 4.3 0.26 10.5 0.1 2.4 2 0 0 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit zf-C2H2_4 PF13894.1 KUM56500.1 - 2.5 8.6 6.4 3.1 8.3 0.2 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger Myosin_tail_1 PF01576.14 KUM56501.1 - 0.0032 15.2 29.5 0.0049 14.6 20.4 1.2 1 0 0 1 1 1 1 Myosin tail eIF2_C PF09173.6 KUM56501.1 - 0.042 13.8 0.4 0.1 12.6 0.3 1.6 1 0 0 1 1 1 0 Initiation factor eIF2 gamma, C terminal DUF3228 PF11539.3 KUM56501.1 - 0.065 12.3 2.4 0.17 10.9 1.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3228) Reo_sigmaC PF04582.7 KUM56501.1 - 0.86 8.7 6.4 0.76 8.9 2.9 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Filament PF00038.16 KUM56501.1 - 2.9 7.2 30.7 0.03 13.7 14.9 2.2 2 1 0 2 2 2 0 Intermediate filament protein IncA PF04156.9 KUM56501.1 - 3.1 7.3 42.7 1.5 8.4 8.3 3.6 2 1 1 3 3 3 0 IncA protein ELF PF03317.8 KUM56501.1 - 7.6 5.7 8.2 0.31 10.3 0.5 2.3 2 1 1 3 3 3 0 ELF protein Baculo_PEP_C PF04513.7 KUM56501.1 - 9.3 6.0 10.5 1.4 8.7 3.4 2.4 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ETF_QO PF05187.8 KUM56502.1 - 2e-44 150.0 0.0 3.2e-44 149.4 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 KUM56502.1 - 2.8e-08 33.0 0.0 0.00049 19.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KUM56502.1 - 2.2e-07 30.0 0.2 0.0009 18.1 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KUM56502.1 - 2.7e-06 27.2 0.0 7.8e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KUM56502.1 - 1.5e-05 24.2 0.0 2.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KUM56502.1 - 9.1e-05 22.4 0.1 0.00015 21.7 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KUM56502.1 - 0.00037 19.0 0.3 0.00058 18.4 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 KUM56502.1 - 0.0006 18.9 0.1 0.0012 18.0 0.1 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KUM56502.1 - 0.00098 19.4 0.1 3 8.2 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KUM56502.1 - 0.0012 18.0 0.0 0.014 14.5 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 KUM56502.1 - 0.0013 18.5 0.0 0.0042 16.8 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KUM56502.1 - 0.0015 18.6 0.0 0.0027 17.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.2 KUM56502.1 - 0.0039 17.5 1.0 0.013 15.8 0.7 1.8 2 0 0 2 2 1 1 4Fe-4S dicluster domain Trp_halogenase PF04820.9 KUM56502.1 - 0.0074 14.9 0.1 0.16 10.5 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.7 KUM56502.1 - 0.029 13.2 0.2 0.045 12.6 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Amino_oxidase PF01593.19 KUM56502.1 - 0.081 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase GIDA PF01134.17 KUM56502.1 - 0.13 11.0 0.4 0.22 10.3 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A TBP PF00352.16 KUM56503.1 - 6.3e-70 230.5 0.1 5.4e-35 118.6 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KUM56503.1 - 0.00015 21.7 0.0 0.51 10.4 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Pollen_allerg_2 PF01620.11 KUM56503.1 - 0.021 15.1 0.4 0.032 14.5 0.3 1.4 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) MFS_1 PF07690.11 KUM56504.1 - 2.6e-28 98.7 34.9 2.6e-28 98.7 24.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily A_deaminase PF00962.17 KUM56505.1 - 2.2e-35 122.1 0.0 2.9e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase DAO PF01266.19 KUM56506.1 - 8.9e-52 176.1 0.6 1.1e-51 175.8 0.4 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KUM56506.1 - 4e-07 29.9 0.3 0.016 14.9 0.0 2.8 2 1 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KUM56506.1 - 1.3e-06 28.4 0.0 0.036 13.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KUM56506.1 - 6.1e-05 22.1 0.1 0.0021 17.0 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.17 KUM56506.1 - 6.5e-05 21.9 0.0 0.00051 19.0 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 KUM56506.1 - 6.5e-05 21.7 0.0 0.0091 14.6 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.1 KUM56506.1 - 0.00014 21.8 0.7 0.0004 20.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KUM56506.1 - 0.00022 21.5 0.0 0.0006 20.1 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KUM56506.1 - 0.0038 17.3 0.0 0.16 12.0 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 KUM56506.1 - 0.0077 15.4 0.0 0.34 10.0 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KUM56506.1 - 0.0093 14.8 0.0 0.84 8.4 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.13 KUM56506.1 - 0.011 15.7 0.0 0.052 13.5 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_3 PF01494.14 KUM56506.1 - 0.1 11.6 0.0 0.22 10.5 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Methyltransf_23 PF13489.1 KUM56507.1 - 2e-25 89.3 0.0 2.8e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM56507.1 - 1.4e-06 28.7 0.0 2.9e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM56507.1 - 0.00049 20.4 0.0 0.001 19.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM56507.1 - 0.0011 19.4 0.0 0.0099 16.3 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM56507.1 - 0.013 16.0 0.0 0.03 14.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 KUM56507.1 - 0.062 12.4 0.0 0.38 9.8 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family RRM_1 PF00076.17 KUM56509.1 - 1.7e-14 53.2 0.1 1.6e-08 34.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM56509.1 - 7.7e-11 41.6 0.0 0.00017 21.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM56509.1 - 1.3e-07 31.5 0.0 1.3e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KUM56509.1 - 0.15 11.8 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif GATase PF00117.23 KUM56510.1 - 0.00011 21.7 0.0 0.00021 20.7 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DUF2321 PF10083.4 KUM56510.1 - 0.025 14.0 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Peptidase_C26 PF07722.8 KUM56510.1 - 0.049 13.0 0.0 0.11 11.9 0.0 1.5 1 1 0 1 1 1 0 Peptidase C26 SNO PF01174.14 KUM56510.1 - 0.088 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Beta_elim_lyase PF01212.16 KUM56511.1 - 8.9e-64 215.4 0.0 1.1e-63 215.1 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KUM56511.1 - 0.0025 16.8 0.0 0.003 16.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KUM56511.1 - 0.0047 16.0 0.0 0.0074 15.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 KUM56511.1 - 0.035 12.4 0.0 0.048 11.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Peptidase_M20 PF01546.23 KUM56513.1 - 2.7e-19 69.4 0.0 3.8e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KUM56513.1 - 2.2e-14 53.1 0.0 2e-13 50.0 0.0 2.1 2 0 0 2 2 2 1 Peptidase dimerisation domain HAD_2 PF13419.1 KUM56514.1 - 1.6e-26 93.6 0.1 2.2e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase zinc-ribbons_6 PF07191.7 KUM56514.1 - 0.07 12.9 0.0 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbons Tachystatin_B PF11478.3 KUM56514.1 - 0.11 12.2 0.0 0.33 10.7 0.0 1.8 1 0 0 1 1 1 0 Antimicrobial chitin binding protein tachystatin B adh_short PF00106.20 KUM56515.1 - 3.5e-24 85.6 0.0 4.9e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM56515.1 - 1.8e-12 47.5 0.0 2.2e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM56515.1 - 1.2e-06 28.3 0.0 2.5e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM56515.1 - 0.00023 20.6 0.1 0.00055 19.4 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KUM56515.1 - 0.0073 16.3 0.0 0.019 14.9 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KUM56515.1 - 0.017 14.0 0.1 0.031 13.1 0.0 1.4 2 0 0 2 2 2 0 RmlD substrate binding domain DUF1464 PF07318.7 KUM56515.1 - 0.018 13.9 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) DAO PF01266.19 KUM56516.1 - 1.3e-50 172.2 0.2 2.2e-50 171.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KUM56516.1 - 5.9e-06 25.5 0.0 1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 KUM56516.1 - 1e-05 25.4 0.1 3.7e-05 23.6 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KUM56516.1 - 6.3e-05 23.1 0.0 0.18 11.8 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM56516.1 - 0.00018 21.3 0.4 0.0042 16.8 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KUM56516.1 - 0.0043 16.9 0.0 0.0068 16.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KUM56516.1 - 0.0075 15.2 0.1 0.016 14.1 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KUM56516.1 - 0.013 14.4 0.1 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KUM56516.1 - 0.19 10.1 0.0 3.3 6.0 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein AA_permease PF00324.16 KUM56517.1 - 2.6e-106 355.8 41.7 3.1e-106 355.5 28.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KUM56517.1 - 1.8e-28 99.2 44.2 2.5e-28 98.7 30.6 1.1 1 0 0 1 1 1 1 Amino acid permease FHA PF00498.21 KUM56518.1 - 9.6e-08 32.0 0.2 1.8e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 FHA domain BRCT PF00533.21 KUM56518.1 - 0.039 14.1 0.0 0.43 10.7 0.0 2.3 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain DUF4138 PF13595.1 KUM56518.1 - 0.065 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4138) Mannosyl_trans PF05007.8 KUM56519.1 - 1.4e-76 257.5 12.5 1.8e-76 257.2 8.6 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 KUM56519.1 - 8e-12 44.7 3.4 8e-12 44.7 2.4 2.1 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 KUM56519.1 - 6.1e-08 32.4 28.8 6.1e-08 32.4 20.0 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF2029) F-box-like PF12937.2 KUM56521.1 - 0.00087 18.9 0.0 0.003 17.2 0.0 2.1 1 0 0 1 1 1 1 F-box-like PD-C2-AF1 PF09310.5 KUM56521.1 - 0.096 11.8 1.5 0.16 11.0 1.1 1.3 1 0 0 1 1 1 0 POU domain, class 2, associating factor 1 Glyco_hydro_12 PF01670.11 KUM56522.1 - 3.9e-08 33.2 0.6 4.3e-08 33.0 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Fungal_trans PF04082.13 KUM56523.1 - 4.9e-20 71.5 0.2 8.9e-20 70.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM56523.1 - 2.8e-06 27.1 14.6 5.3e-06 26.2 10.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3913 PF13052.1 KUM56523.1 - 0.23 11.4 0.0 0.81 9.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3913) IMS PF00817.15 KUM56524.1 - 6.3e-43 146.1 0.3 1.3e-42 145.1 0.2 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KUM56524.1 - 3.7e-17 62.4 0.1 8.8e-17 61.2 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KUM56524.1 - 1e-06 28.4 0.0 3.1e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif BAF PF02961.9 KUM56524.1 - 0.05 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Barrier to autointegration factor DUF3712 PF12505.3 KUM56525.1 - 6.8e-30 103.6 0.5 6.8e-30 103.6 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Rhodanese PF00581.15 KUM56526.1 - 1.4e-17 64.0 0.0 3.6e-09 36.9 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Glyco_hydro_2 PF00703.16 KUM56527.1 - 1.7e-14 54.1 0.1 6.7e-14 52.2 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 KUM56527.1 - 1e-11 44.6 2.0 1.1e-11 44.5 0.3 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KUM56527.1 - 0.012 14.5 0.0 0.026 13.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Syntaxin PF00804.20 KUM56528.1 - 0.079 13.1 1.8 8.4 6.6 0.0 2.4 2 0 0 2 2 2 0 Syntaxin Kinesin PF00225.18 KUM56529.1 - 3.3e-111 371.2 0.8 3.3e-111 371.2 0.5 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bind PF13931.1 KUM56529.1 - 8.1e-08 32.5 3.0 8.1e-08 32.5 2.1 5.0 5 1 1 6 6 6 1 Kinesin-associated microtubule-binding Baculo_PEP_C PF04513.7 KUM56529.1 - 0.00044 20.0 22.6 0.043 13.6 0.0 6.2 2 1 4 7 7 7 4 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.16 KUM56529.1 - 0.064 12.7 0.1 0.064 12.7 0.1 4.6 2 1 1 3 3 3 0 Intermediate filament protein DUF3584 PF12128.3 KUM56529.1 - 0.24 8.6 53.3 0.47 7.7 4.6 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF3584) UPF0183 PF03676.9 KUM56530.1 - 6e-38 130.4 0.0 7e-27 94.0 0.0 4.0 3 1 0 3 3 3 3 Uncharacterised protein family (UPF0183) Translin PF01997.11 KUM56531.1 - 1.2e-68 230.6 0.1 1.4e-68 230.4 0.1 1.0 1 0 0 1 1 1 1 Translin family DUF2990 PF11693.3 KUM56531.1 - 0.099 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2990) RPEL PF02755.10 KUM56532.1 - 7.7e-28 95.0 16.4 9.4e-10 37.5 0.6 3.5 3 0 0 3 3 3 3 RPEL repeat DUF4174 PF13778.1 KUM56532.1 - 0.13 12.3 1.7 1.8 8.6 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4174) PIN_4 PF13638.1 KUM56533.1 - 9.6e-05 22.4 0.1 0.035 14.1 0.0 2.4 2 0 0 2 2 2 2 PIN domain DUF3464 PF11947.3 KUM56534.1 - 0.94 8.9 6.4 0.91 8.9 4.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF3899 PF13038.1 KUM56534.1 - 1.2 9.3 7.2 1.2 9.3 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) SR-25 PF10500.4 KUM56534.1 - 1.6 8.1 24.0 1.7 8.0 16.7 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MRL1 PF13003.2 KUM56534.1 - 1.9 8.3 11.5 2.2 8.1 8.0 1.0 1 0 0 1 1 1 0 Ribosomal protein L1 OAD_gamma PF04277.8 KUM56534.1 - 3.2 8.2 5.5 3.2 8.2 3.8 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain YqfQ PF14181.1 KUM56534.1 - 3.3 7.7 10.1 3.5 7.6 7.0 1.0 1 0 0 1 1 1 0 YqfQ-like protein O-ag_pol_Wzy PF14296.1 KUM56534.1 - 3.6 6.0 5.4 3.5 6.0 3.8 1.0 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy DUF2058 PF09831.4 KUM56534.1 - 3.7 7.3 13.0 3.6 7.4 9.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Peptidase_S49_N PF08496.5 KUM56534.1 - 6.5 6.5 14.8 6.8 6.4 10.2 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Med19 PF10278.4 KUM56534.1 - 7.2 6.2 26.0 8.2 6.0 18.0 1.0 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Cnd1_N PF12922.2 KUM56534.1 - 7.3 6.1 8.0 7.5 6.1 5.6 1.1 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term MIP-T3 PF10243.4 KUM56534.1 - 9.3 4.5 16.0 9.7 4.5 11.1 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Clr5 PF14420.1 KUM56537.1 - 4.2e-13 48.9 2.0 7.2e-13 48.2 1.4 1.4 1 0 0 1 1 1 1 Clr5 domain ADH_zinc_N PF00107.21 KUM56538.1 - 8.7e-31 106.1 1.0 1.4e-30 105.4 0.7 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KUM56538.1 - 6.4e-09 36.7 0.0 1.6e-08 35.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM56538.1 - 1.9e-07 30.7 0.0 1.6e-06 27.8 0.0 2.6 3 1 1 4 4 4 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 KUM56538.1 - 0.019 14.9 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.16 KUM56538.1 - 0.075 12.6 4.1 0.079 12.5 1.3 1.9 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HupF_HypC PF01455.13 KUM56538.1 - 0.15 12.0 0.4 0.79 9.7 0.1 2.2 2 0 0 2 2 2 0 HupF/HypC family Glyco_tranf_2_3 PF13641.1 KUM56539.1 - 6.5e-25 88.2 0.1 8.7e-25 87.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KUM56539.1 - 8.3e-07 28.4 0.0 0.00081 18.7 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KUM56539.1 - 2.4e-05 24.0 0.0 3.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 ATP12 PF07542.6 KUM56541.1 - 1.2e-35 122.1 0.7 1.8e-35 121.5 0.2 1.5 2 0 0 2 2 2 1 ATP12 chaperone protein Syja_N PF02383.13 KUM56543.1 - 8.4e-96 320.4 0.0 1.7e-95 319.4 0.0 1.5 1 0 0 1 1 1 1 SacI homology domain DUF2454 PF10521.4 KUM56544.1 - 1.1e-88 296.9 1.0 1.5e-88 296.5 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) Pex2_Pex12 PF04757.9 KUM56545.1 - 1.2e-56 191.7 3.0 1.5e-56 191.4 2.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 KUM56545.1 - 9.6e-06 25.3 2.2 1.7e-05 24.5 1.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KUM56545.1 - 1.6e-05 24.8 4.0 1.9e-05 24.6 1.8 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KUM56545.1 - 0.0031 17.3 2.0 0.0031 17.3 1.4 1.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KUM56545.1 - 0.017 14.7 1.6 0.031 13.9 1.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KUM56545.1 - 0.028 14.0 1.9 0.051 13.2 1.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF520 PF04461.8 KUM56546.1 - 0.04 13.7 0.0 0.058 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF520) Oligomerisation PF02410.10 KUM56547.1 - 1.3e-05 25.1 0.0 0.00011 22.1 0.0 2.3 1 1 0 1 1 1 1 Oligomerisation domain PolyA_pol PF01743.15 KUM56548.1 - 2.2e-20 73.1 1.1 1e-19 70.9 0.8 2.1 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 KUM56548.1 - 2.5e-07 30.1 0.1 7.5e-07 28.6 0.1 1.9 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 KUM56548.1 - 0.00091 19.0 0.4 0.0019 18.0 0.1 1.7 2 0 0 2 2 2 1 tRNA nucleotidyltransferase domain 2 putative TRAPPC-Trs85 PF12739.2 KUM56549.1 - 2.8e-121 405.0 1.8 4.1e-121 404.5 1.2 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPPII_N PF12583.3 KUM56549.1 - 0.12 12.5 0.3 19 5.3 0.0 2.4 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal TPR_19 PF14559.1 KUM56549.1 - 0.15 12.4 0.4 2.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Bac_luciferase PF00296.15 KUM56550.1 - 3.3e-59 200.5 0.2 5.2e-59 199.8 0.1 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase SSF PF00474.12 KUM56551.1 - 5.8e-24 84.4 31.5 9.1e-24 83.8 21.8 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family FAD_binding_4 PF01565.18 KUM56552.1 - 4.9e-22 77.9 0.0 7.3e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KUM56552.1 - 4.9e-06 26.3 0.1 1.4e-05 24.8 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like Bim_N PF06773.6 KUM56553.1 - 0.05 13.3 2.0 0.086 12.6 1.4 1.3 1 0 0 1 1 1 0 Bim protein N-terminus Cation_efflux PF01545.16 KUM56554.1 - 0.0083 15.2 0.5 0.028 13.5 0.1 1.9 2 0 0 2 2 2 1 Cation efflux family DUF975 PF06161.6 KUM56554.1 - 0.17 11.5 7.0 0.049 13.3 1.5 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF975) Sugar_tr PF00083.19 KUM56555.1 - 5.9e-60 203.1 31.5 7.3e-60 202.8 21.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM56555.1 - 1e-17 63.8 39.5 1e-17 63.8 27.4 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily RhodobacterPufX PF11511.3 KUM56555.1 - 0.054 12.8 0.2 0.054 12.8 0.1 3.0 3 0 0 3 3 3 0 Intrinsic membrane protein PufX DUF3431 PF11913.3 KUM56556.1 - 7.2e-85 283.9 0.0 9.1e-85 283.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) ADH_N PF08240.7 KUM56557.1 - 4.9e-06 26.2 0.0 1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2OG-FeII_Oxy_2 PF13532.1 KUM56558.1 - 3e-28 98.9 0.0 5.6e-28 98.0 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 KUM56560.1 - 1.4e-27 96.3 33.4 1.4e-27 96.3 23.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM56560.1 - 6.7e-05 21.2 3.7 6.7e-05 21.2 2.6 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1049 PF06305.6 KUM56560.1 - 0.9 9.0 3.1 6.1 6.4 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Tim17 PF02466.14 KUM56561.1 - 0.00048 20.1 0.8 0.00096 19.1 0.5 1.6 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Kinesin PF00225.18 KUM56563.1 - 3.2e-114 381.1 0.2 1.1e-113 379.3 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain AAA_33 PF13671.1 KUM56563.1 - 0.036 13.9 0.0 0.22 11.3 0.0 2.4 1 0 0 1 1 1 0 AAA domain PMSR PF01625.16 KUM56564.1 - 3.4e-14 53.0 1.2 4.6e-14 52.5 0.8 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase PMSR PF01625.16 KUM56565.1 - 1.7e-25 89.7 0.1 1.9e-25 89.5 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Ribosomal_L34e PF01199.13 KUM56566.1 - 0.045 13.9 0.8 0.081 13.1 0.5 1.4 1 0 0 1 1 1 0 Ribosomal protein L34e MAP65_ASE1 PF03999.7 KUM56566.1 - 3.4 6.1 5.0 4.7 5.6 2.9 1.4 1 1 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) cNMP_binding PF00027.24 KUM56568.1 - 1.1e-37 127.7 0.0 7.8e-21 73.6 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 KUM56568.1 - 2.6e-15 54.6 5.2 1.7 8.9 0.1 9.7 10 0 0 10 10 10 3 Leucine Rich repeat LRR_8 PF13855.1 KUM56568.1 - 1.1e-06 28.2 0.1 0.071 12.8 0.3 4.3 3 1 2 5 5 5 2 Leucine rich repeat LRR_1 PF00560.28 KUM56568.1 - 2.8e-06 26.6 4.6 19 5.7 0.1 8.1 7 2 1 8 8 8 0 Leucine Rich Repeat LRR_4 PF12799.2 KUM56568.1 - 1.9e-05 24.1 2.9 0.19 11.3 0.1 5.2 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KUM56568.1 - 4.3e-05 23.1 0.1 0.00013 21.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KUM56568.1 - 6.4e-05 22.5 0.6 0.00029 20.4 0.4 2.1 1 0 0 1 1 1 1 F-box domain LRR_7 PF13504.1 KUM56568.1 - 0.0015 18.3 8.1 42 4.9 0.0 7.1 7 0 0 7 7 7 0 Leucine rich repeat Ste50p-SAM PF09235.5 KUM56568.1 - 0.31 11.0 3.1 4.5 7.3 0.3 3.1 3 0 0 3 3 3 0 Ste50p, sterile alpha motif DUF3425 PF11905.3 KUM56569.1 - 3e-36 124.2 0.5 4.7e-36 123.6 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) FAD_binding_4 PF01565.18 KUM56570.1 - 2.9e-22 78.6 1.3 6.6e-22 77.4 0.9 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KUM56570.1 - 0.00022 21.0 0.0 0.00057 19.7 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Aldo_ket_red PF00248.16 KUM56571.1 - 6e-72 241.8 0.0 6.8e-72 241.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ank_2 PF12796.2 KUM56572.1 - 1.9e-36 124.2 1.3 4e-20 71.9 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KUM56572.1 - 2e-34 115.6 4.0 6.7e-09 35.1 0.1 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 KUM56572.1 - 4.3e-28 97.1 1.5 9.7e-11 41.8 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM56572.1 - 1.7e-22 77.2 1.2 0.00016 21.5 0.1 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 KUM56572.1 - 2.9e-19 68.6 3.0 2.5e-10 40.2 0.1 4.0 2 1 0 3 3 3 3 Ankyrin repeats (many copies) zf-C2H2 PF00096.21 KUM56572.1 - 0.0062 16.8 0.1 0.03 14.6 0.0 2.3 1 0 0 1 1 1 1 Zinc finger, C2H2 type Syntaxin_2 PF14523.1 KUM56572.1 - 0.12 12.4 0.7 9.5 6.3 0.0 2.6 2 0 0 2 2 2 0 Syntaxin-like protein Polysacc_synt_2 PF02719.10 KUM56572.1 - 0.15 10.9 0.0 1.4 7.7 0.0 2.0 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein zf-C2H2_4 PF13894.1 KUM56572.1 - 1.4 9.3 3.7 1.6 9.2 0.1 3.0 4 0 0 4 4 4 0 C2H2-type zinc finger Flocculin_t3 PF13928.1 KUM56573.1 - 0.003 17.6 3.2 0.003 17.6 2.2 3.0 2 1 1 3 3 3 1 Flocculin type 3 repeat Zn-ribbon_8 PF09723.5 KUM56573.1 - 0.076 12.9 0.4 0.13 12.2 0.0 1.5 2 0 0 2 2 2 0 Zinc ribbon domain MOSC PF03473.12 KUM56574.1 - 7.1e-17 61.1 0.0 1.1e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 KUM56574.1 - 4.2e-13 49.0 0.0 8.5e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain SHMT PF00464.14 KUM56575.1 - 1.1e-198 659.5 0.0 1.3e-198 659.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Mg_trans_NIPA PF05653.9 KUM56576.1 - 3.5e-90 302.0 24.8 4.9e-90 301.5 17.2 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KUM56576.1 - 2e-07 31.1 4.8 2e-07 31.1 3.3 3.3 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KUM56576.1 - 8.7e-06 25.7 6.0 8.7e-06 25.7 4.1 3.4 3 1 1 4 4 4 1 EamA-like transporter family DUF1894 PF08979.6 KUM56576.1 - 0.19 11.8 0.2 6.6 6.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1894) Patatin PF01734.17 KUM56577.1 - 1.2e-27 97.2 0.0 2.5e-27 96.1 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase KilA-N PF04383.8 KUM56578.1 - 0.00023 20.7 0.0 0.0053 16.3 0.0 2.5 2 1 0 2 2 2 1 KilA-N domain PTCB-BRCT PF12738.2 KUM56579.1 - 0.0064 16.3 1.9 0.069 13.0 0.0 2.4 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 KUM56579.1 - 0.034 14.2 0.0 0.071 13.2 0.0 1.6 1 1 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain AMP-binding PF00501.23 KUM56580.1 - 8.1e-61 205.6 0.0 1.2e-60 205.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.19 KUM56580.1 - 9.9e-15 53.3 9.1 4.3e-06 25.9 0.0 6.9 6 1 0 6 6 6 2 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.20 KUM56580.1 - 2.5e-11 43.6 0.0 5.8e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep_2 PF14602.1 KUM56580.1 - 5.4e-07 29.0 11.0 1.1 8.8 0.1 6.1 6 0 0 6 6 6 4 Hexapeptide repeat of succinyl-transferase AMP-binding_C PF13193.1 KUM56580.1 - 0.052 14.4 1.0 1.3 9.9 0.2 3.0 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain GH3 PF03321.8 KUM56580.1 - 0.059 11.8 0.0 1.7 7.0 0.1 2.1 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Mlo PF03094.10 KUM56580.1 - 0.074 11.1 0.8 0.12 10.4 0.5 1.2 1 0 0 1 1 1 0 Mlo family SnoaL_4 PF13577.1 KUM56581.1 - 6e-20 71.4 0.2 6.9e-20 71.2 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF1993 PF09351.5 KUM56582.1 - 9.1e-50 168.7 0.0 1e-49 168.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) MDMPI_N PF11716.3 KUM56582.1 - 0.096 13.1 0.0 0.13 12.6 0.0 1.1 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain NUC202 PF08166.7 KUM56587.1 - 0.034 14.0 0.1 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 NUC202 domain AMP-binding PF00501.23 KUM56588.1 - 3.6e-80 269.4 0.0 5.1e-80 268.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KUM56588.1 - 2e-49 168.0 0.2 2.9e-49 167.5 0.1 1.2 1 0 0 1 1 1 1 Condensation domain NAD_binding_4 PF07993.7 KUM56588.1 - 4.6e-39 133.8 0.0 1.8e-38 131.8 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KUM56588.1 - 4.5e-14 52.4 0.0 8.5e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HxxPF_rpt PF13745.1 KUM56588.1 - 7.9e-11 42.1 0.0 2.2e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 HxxPF-repeated domain 3Beta_HSD PF01073.14 KUM56588.1 - 1e-07 30.9 0.0 1.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 KUM56588.1 - 6.7e-07 29.4 0.1 2.9e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.1 KUM56588.1 - 0.015 15.3 0.0 0.04 13.9 0.0 1.7 1 1 0 1 1 1 0 NADH(P)-binding Semialdhyde_dh PF01118.19 KUM56588.1 - 0.059 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 KUM56588.1 - 0.075 12.9 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 short chain dehydrogenase AATase PF07247.7 KUM56588.1 - 0.36 9.3 0.1 0.57 8.6 0.0 1.2 1 0 0 1 1 1 0 Alcohol acetyltransferase ADH_zinc_N PF00107.21 KUM56589.1 - 1.8e-10 40.4 0.0 3.1e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ketoacyl-synt PF00109.21 KUM56590.1 - 2e-75 253.5 0.0 8.8e-75 251.4 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 KUM56590.1 - 1.5e-53 181.9 0.0 3e-53 180.9 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KUM56590.1 - 2.6e-48 164.9 0.0 4.2e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KUM56590.1 - 3e-31 107.7 0.0 7.1e-31 106.5 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 KUM56590.1 - 2.4e-06 26.7 0.0 4.6e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain KR PF08659.5 KUM56592.1 - 5e-51 172.9 0.0 8.3e-51 172.2 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KUM56592.1 - 9.1e-40 136.2 0.0 2e-39 135.2 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.20 KUM56592.1 - 5.5e-06 26.5 0.1 3.6e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site Pilin_PilX PF11530.3 KUM56592.1 - 0.053 13.1 0.0 6.3 6.4 0.0 2.4 2 0 0 2 2 2 0 Minor type IV pilin, PilX Zn_clus PF00172.13 KUM56594.1 - 9.2e-08 31.8 10.9 1.3e-07 31.3 7.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bac_rhamnosid PF05592.6 KUM56596.1 - 0.00074 17.8 0.0 0.072 11.2 0.0 2.1 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase Laminin_G_3 PF13385.1 KUM56596.1 - 0.0028 17.8 0.1 0.0075 16.5 0.1 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Aminotran_1_2 PF00155.16 KUM56599.1 - 1.6e-76 257.6 0.0 1.8e-76 257.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KUM56599.1 - 0.0046 16.1 0.0 0.0066 15.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase adh_short PF00106.20 KUM56600.1 - 3.2e-22 79.2 0.0 4.2e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM56600.1 - 3e-09 36.7 0.0 6.7e-09 35.6 0.0 1.5 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 KUM56600.1 - 1.8e-08 34.4 0.0 2.3e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KUM56600.1 - 0.03 14.3 0.3 0.96 9.4 0.1 3.1 1 1 1 2 2 2 0 NADH(P)-binding AAA_26 PF13500.1 KUM56600.1 - 0.083 12.4 1.8 1.2 8.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain Polysacc_synt_2 PF02719.10 KUM56600.1 - 0.16 10.7 0.0 1 8.1 0.0 2.0 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_6 PF03737.10 KUM56601.1 - 7.3e-41 139.6 9.9 4.3e-24 85.1 2.4 2.1 2 0 0 2 2 2 2 Demethylmenaquinone methyltransferase Osmo_CC PF08946.5 KUM56602.1 - 0.0035 17.3 1.3 0.006 16.5 0.9 1.3 1 0 0 1 1 1 1 Osmosensory transporter coiled coil Gly-zipper_OmpA PF13436.1 KUM56602.1 - 0.033 13.8 1.1 3.3 7.3 0.0 2.2 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Glyco_hydro_61 PF03443.9 KUM56605.1 - 4.5e-43 147.5 0.1 5.8e-43 147.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Fmp27 PF10344.4 KUM56607.1 - 6e-240 798.4 0.0 6e-240 798.4 0.0 2.5 3 0 0 3 3 3 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 KUM56607.1 - 3e-165 550.5 0.1 3e-165 550.5 0.0 4.0 4 0 0 4 4 4 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 KUM56607.1 - 4.3e-150 500.2 12.6 2.7e-149 497.6 8.7 2.5 1 1 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 KUM56607.1 - 2.6e-55 186.4 0.1 5.9e-55 185.3 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.4 KUM56607.1 - 3.7e-52 176.3 0.0 1.1e-51 174.8 0.0 1.9 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.4 KUM56607.1 - 1.5e-28 99.2 0.1 9.2e-28 96.7 0.0 2.6 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain LysM PF01476.15 KUM56608.1 - 1.3e-14 53.7 0.7 0.00033 20.4 0.0 3.3 3 0 0 3 3 3 3 LysM domain adh_short PF00106.20 KUM56610.1 - 2.6e-26 92.5 0.7 3.3e-26 92.1 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM56610.1 - 3.3e-16 59.7 0.0 4.1e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM56610.1 - 9.2e-14 51.5 0.2 1.3e-13 51.0 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM56610.1 - 2.6e-06 27.0 0.0 3.8e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KUM56610.1 - 0.0035 17.3 0.0 0.011 15.7 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 KUM56610.1 - 0.0049 16.0 0.0 0.0065 15.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.8 KUM56610.1 - 0.05 12.8 0.1 0.075 12.2 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 KUM56610.1 - 0.057 12.3 0.2 0.088 11.6 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Glyco_hydro_18 PF00704.23 KUM56611.1 - 9.1e-50 170.0 6.3 1.5e-49 169.3 2.9 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Hce2 PF14856.1 KUM56611.1 - 5.2e-20 71.1 0.6 2.2e-19 69.1 0.4 2.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor LysM PF01476.15 KUM56611.1 - 2.8e-08 33.5 1.4 5.9e-05 22.8 0.0 3.5 3 0 0 3 3 3 2 LysM domain Chitin_bind_1 PF00187.14 KUM56611.1 - 7.2e-06 25.8 3.5 7.2e-06 25.8 2.4 4.4 4 0 0 4 4 4 1 Chitin recognition protein 2OG-FeII_Oxy_3 PF13640.1 KUM56613.1 - 8e-10 39.1 0.0 1.4e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KUM56613.1 - 6.3e-05 22.5 0.0 0.00015 21.3 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sugar_tr PF00083.19 KUM56614.1 - 7.8e-89 298.2 32.4 1e-88 297.9 22.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM56614.1 - 7.6e-23 80.7 35.2 7.6e-23 80.7 24.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KUM56614.1 - 0.0001 20.7 3.9 0.0001 20.7 2.7 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1634 PF07843.6 KUM56615.1 - 0.0076 15.8 0.4 0.023 14.3 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1634) 2TM PF13239.1 KUM56615.1 - 1.4 9.0 11.8 0.086 12.9 2.8 2.7 2 1 1 3 3 3 0 2TM domain ADH_N PF08240.7 KUM56616.1 - 1.4e-18 66.6 5.1 2.6e-18 65.7 3.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM56616.1 - 6.1e-12 45.2 0.0 1.1e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KUM56616.1 - 0.00045 19.4 0.1 0.00079 18.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KUM56616.1 - 0.0012 18.4 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 KUM56616.1 - 0.092 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Totivirus_coat PF05518.6 KUM56617.1 - 1.8 6.2 4.0 2.4 5.8 2.8 1.1 1 0 0 1 1 1 0 Totivirus coat protein IQ PF00612.22 KUM56618.1 - 0.00052 19.4 0.8 0.0015 17.9 0.5 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif Thiolase_C PF02803.13 KUM56619.1 - 1.1e-10 40.9 1.3 1.7e-09 37.1 0.0 2.8 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KUM56619.1 - 4.3e-07 29.5 0.0 2.9e-05 23.6 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 KUM56619.1 - 2.4e-05 23.4 0.0 0.0005 19.1 0.0 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 KUM56619.1 - 9.8e-05 21.9 0.3 0.0002 20.9 0.2 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.6 KUM56619.1 - 0.0043 15.5 0.0 0.0084 14.5 0.0 1.4 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) DUF3208 PF11482.3 KUM56619.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) GFA PF04828.9 KUM56620.1 - 1e-14 54.1 0.1 1.6e-14 53.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Cys_rich_CWC PF14375.1 KUM56620.1 - 0.89 9.5 5.8 0.28 11.1 1.8 1.7 2 0 0 2 2 2 0 Cysteine-rich CWC Myb_DNA-binding PF00249.26 KUM56625.1 - 0.016 15.2 1.3 0.085 12.9 0.8 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain Hemerythrin PF01814.18 KUM56626.1 - 6.7e-11 42.4 0.1 1.1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Sds3 PF08598.6 KUM56627.1 - 2.8e-48 164.1 8.2 1.8e-47 161.5 5.7 2.0 1 1 0 1 1 1 1 Sds3-like Methyltransf_32 PF13679.1 KUM56628.1 - 0.064 12.9 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CMD PF02627.15 KUM56630.1 - 1.6e-18 66.3 0.0 2.7e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family NAD_binding_9 PF13454.1 KUM56632.1 - 2.1e-44 151.0 0.0 4.2e-44 150.0 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding ThiF PF00899.16 KUM56632.1 - 0.088 12.6 0.0 6.4 6.6 0.0 2.9 3 0 0 3 3 3 0 ThiF family Zn_clus PF00172.13 KUM56634.1 - 5.9e-07 29.2 10.3 5.9e-07 29.2 7.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.23 KUM56635.1 - 1.1e-79 267.8 0.0 1.6e-79 267.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KUM56635.1 - 2.3e-36 124.9 0.0 4e-36 124.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding_C PF13193.1 KUM56635.1 - 1.9e-08 35.1 0.0 8.3e-08 33.0 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 KUM56635.1 - 8.6e-08 31.8 0.0 2.6e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KUM56635.1 - 0.0004 20.6 0.0 0.0011 19.2 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Pyridoxal_deC PF00282.14 KUM56636.1 - 1.4e-31 109.2 0.0 1.9e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KUM56636.1 - 4.4e-05 22.3 0.0 5.7e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V UCR_hinge PF02320.11 KUM56636.1 - 0.035 14.0 0.0 0.39 10.6 0.0 2.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Ank_2 PF12796.2 KUM56637.1 - 3.7e-46 155.3 11.0 4e-13 49.4 0.1 4.7 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KUM56637.1 - 5.5e-43 142.7 5.3 3.4e-06 26.5 0.0 8.2 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.1 KUM56637.1 - 1.4e-30 105.0 11.1 1.2e-10 41.5 0.1 6.1 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM56637.1 - 9.9e-29 98.7 12.0 1.7e-07 31.2 0.2 6.4 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM56637.1 - 1.4e-28 96.0 6.0 0.0012 18.8 0.0 7.7 8 0 0 8 8 8 7 Ankyrin repeat EIAV_Rev PF11129.3 KUM56638.1 - 0.1 12.5 1.5 0.12 12.3 1.1 1.1 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus KIAA1430 PF13879.1 KUM56638.1 - 0.14 12.6 3.4 0.16 12.4 2.4 1.2 1 0 0 1 1 1 0 KIAA1430 homologue HALZ PF02183.13 KUM56639.1 - 0.0035 17.0 0.3 0.005 16.5 0.2 1.3 1 0 0 1 1 1 1 Homeobox associated leucine zipper GAS PF13851.1 KUM56639.1 - 0.0053 15.9 0.8 0.0068 15.6 0.6 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Fez1 PF06818.10 KUM56639.1 - 0.0075 16.3 0.2 0.0093 16.0 0.2 1.1 1 0 0 1 1 1 1 Fez1 Prominin PF05478.6 KUM56639.1 - 0.0087 13.6 0.3 0.01 13.4 0.2 1.0 1 0 0 1 1 1 1 Prominin DUF684 PF05075.9 KUM56639.1 - 0.029 12.9 0.2 0.036 12.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF684) Gag_p17 PF00540.13 KUM56639.1 - 0.034 13.9 0.1 0.046 13.5 0.1 1.2 1 0 0 1 1 1 0 gag gene protein p17 (matrix protein) Kinesin-relat_1 PF12711.2 KUM56639.1 - 0.035 14.4 0.9 0.065 13.6 0.6 1.4 1 0 0 1 1 1 0 Kinesin motor DUF972 PF06156.8 KUM56639.1 - 0.07 13.4 0.5 0.096 13.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.10 KUM56639.1 - 0.18 11.2 3.0 0.27 10.7 2.1 1.2 1 0 0 1 1 1 0 Septum formation initiator Fungal_trans_2 PF11951.3 KUM56640.1 - 0.017 13.7 2.2 0.023 13.2 1.5 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Death PF00531.17 KUM56640.1 - 0.071 12.8 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Death domain His_Phos_2 PF00328.17 KUM56641.1 - 1.6e-18 67.2 0.0 2.9e-18 66.3 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Herpes_pp38 PF04846.8 KUM56642.1 - 0.092 12.0 0.9 0.16 11.2 0.5 1.5 1 1 0 1 1 1 0 Herpesvirus pp38 phosphoprotein Acetyltransf_1 PF00583.19 KUM56643.1 - 1.1e-09 38.2 0.0 1.7e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KUM56643.1 - 0.00011 22.0 0.0 0.00065 19.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KUM56643.1 - 0.00062 19.8 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KUM56643.1 - 0.0011 19.0 0.0 0.0027 17.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KUM56643.1 - 0.0024 17.7 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 KUM56643.1 - 0.0047 16.6 0.0 0.0084 15.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein MFS_1 PF07690.11 KUM56645.1 - 4e-20 71.8 13.9 4.6e-20 71.6 9.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KUM56645.1 - 6.1e-05 21.5 6.4 9.9e-05 20.9 4.4 1.3 1 0 0 1 1 1 1 MFS/sugar transport protein YesK PF14150.1 KUM56645.1 - 0.011 15.8 2.3 0.011 15.8 1.6 2.9 3 0 0 3 3 3 0 YesK-like protein Sm_multidrug_ex PF06695.6 KUM56645.1 - 0.033 14.3 2.0 0.042 13.9 0.2 1.9 2 0 0 2 2 2 0 Putative small multi-drug export protein DUF805 PF05656.9 KUM56645.1 - 1.2 8.9 6.1 0.74 9.6 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF805) FtsX PF02687.16 KUM56645.1 - 6.1 6.6 10.3 7.1 6.4 0.8 2.5 2 0 0 2 2 2 0 FtsX-like permease family Sugar_tr PF00083.19 KUM56646.1 - 2.6e-143 477.8 28.5 3e-143 477.6 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM56646.1 - 5.9e-23 81.1 35.9 1.3e-16 60.2 8.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_75 PF07335.6 KUM56647.1 - 2.3e-14 53.5 0.0 2.8e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 Med3 PF11593.3 KUM56647.1 - 0.017 14.4 0.5 0.017 14.4 0.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CBM_1 PF00734.13 KUM56648.1 - 1.4e-12 47.0 11.9 2.9e-12 45.9 8.2 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Carboxyl_trans PF01039.17 KUM56649.1 - 2.2e-142 474.9 0.0 2.6e-142 474.6 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Bax1-I PF01027.15 KUM56651.1 - 4.4 6.8 8.0 5.1 6.6 5.6 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Protoglobin PF11563.3 KUM56652.1 - 0.1 12.2 0.1 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Protoglobin Acyl-CoA_dh_1 PF00441.19 KUM56653.1 - 1.2e-40 139.0 1.1 1.9e-40 138.3 0.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KUM56653.1 - 2.7e-32 111.6 0.1 5.5e-32 110.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KUM56653.1 - 4.5e-16 58.1 0.1 4.6e-14 51.6 0.1 2.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KUM56653.1 - 7.6e-16 58.5 0.2 1.3e-15 57.8 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pkinase PF00069.20 KUM56654.1 - 0.0025 17.0 0.1 0.38 9.8 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain CPSase_L_D2 PF02786.12 KUM56655.1 - 1.4e-73 246.6 0.0 2.9e-73 245.6 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 KUM56655.1 - 6.3e-37 125.8 0.0 1.6e-36 124.5 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 KUM56655.1 - 4.6e-34 116.8 0.0 1.2e-33 115.4 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 KUM56655.1 - 1.9e-18 66.8 0.0 4.7e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KUM56655.1 - 2.3e-18 65.5 0.3 7.5e-18 63.9 0.2 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KUM56655.1 - 6e-13 48.2 0.0 1.7e-12 46.7 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KUM56655.1 - 6.2e-10 38.7 0.0 1.5e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KUM56655.1 - 2.8e-07 30.0 0.0 5.3e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 KUM56655.1 - 2.7e-06 26.9 0.0 0.0023 17.5 0.0 2.9 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.9 KUM56655.1 - 2.4e-05 24.2 0.0 5.1e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 KUM56655.1 - 0.0013 18.3 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD_3 PF13437.1 KUM56655.1 - 0.0031 17.8 0.0 5.2 7.4 0.0 2.8 2 0 0 2 2 2 2 HlyD family secretion protein RimK PF08443.6 KUM56655.1 - 0.0095 15.4 0.0 0.095 12.1 0.0 2.1 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.1 KUM56655.1 - 0.018 14.1 0.0 0.046 12.8 0.0 1.7 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp GCV_H PF01597.14 KUM56655.1 - 0.079 12.6 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 Glycine cleavage H-protein 2OG-Fe_Oxy_2 PF10014.4 KUM56656.1 - 0.083 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe dioxygenase GATase PF00117.23 KUM56657.1 - 6.7e-36 123.5 0.0 1.4e-35 122.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 KUM56657.1 - 1.5e-33 114.3 0.0 5.2e-33 112.6 0.0 1.9 2 0 0 2 2 2 1 GMP synthase C terminal domain NAD_synthase PF02540.12 KUM56657.1 - 1e-09 37.6 0.0 4.3e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 NAD synthase tRNA_Me_trans PF03054.11 KUM56657.1 - 8.1e-05 21.3 0.1 0.00019 20.0 0.0 1.6 2 0 0 2 2 2 1 tRNA methyl transferase Peptidase_C26 PF07722.8 KUM56657.1 - 0.00034 20.1 0.3 0.0029 17.0 0.1 2.3 1 1 0 1 1 1 1 Peptidase C26 PAPS_reduct PF01507.14 KUM56657.1 - 0.00082 19.2 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.14 KUM56657.1 - 0.0018 17.4 0.1 0.0025 16.9 0.1 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 KUM56657.1 - 0.026 13.8 0.0 0.16 11.2 0.0 2.0 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC ThiI PF02568.9 KUM56657.1 - 0.04 13.3 0.0 0.079 12.4 0.0 1.5 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.15 KUM56657.1 - 0.15 11.5 0.1 0.35 10.3 0.0 1.7 1 1 0 1 1 1 0 PP-loop family PDCD2_C PF04194.8 KUM56658.1 - 1.7e-52 177.3 0.0 3.1e-52 176.4 0.0 1.4 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain A2L_zn_ribbon PF08792.5 KUM56658.1 - 0.026 13.9 0.2 2.7 7.5 0.0 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain GRAM PF02893.15 KUM56660.1 - 4.6e-29 99.7 1.5 2e-17 62.4 0.0 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.15 KUM56660.1 - 3e-23 82.1 0.0 5.6e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 KUM56660.1 - 8.7e-17 61.2 0.0 9.1e-16 57.9 0.0 2.6 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 KUM56660.1 - 1.8e-08 34.5 0.2 9.6e-08 32.2 0.1 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 KUM56660.1 - 7e-05 22.6 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 KUM56660.1 - 0.00029 20.8 0.0 0.00073 19.5 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain UDPGT PF00201.13 KUM56660.1 - 0.018 13.6 0.0 0.031 12.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Spc7 PF08317.6 KUM56662.1 - 0.00093 17.9 7.6 0.0011 17.7 5.2 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein NTR2 PF15458.1 KUM56662.1 - 0.0011 18.2 11.3 0.074 12.2 0.6 2.1 1 1 1 2 2 2 2 Nineteen complex-related protein 2 Prefoldin_2 PF01920.15 KUM56662.1 - 0.0023 17.6 8.5 0.31 10.8 2.2 2.1 2 0 0 2 2 2 2 Prefoldin subunit DUF4140 PF13600.1 KUM56662.1 - 0.0026 18.1 1.0 0.97 9.9 0.2 2.1 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) TBPIP PF07106.8 KUM56662.1 - 0.0076 15.8 8.0 0.01 15.3 5.5 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tropomyosin PF00261.15 KUM56662.1 - 0.013 14.5 7.3 0.016 14.3 5.1 1.1 1 0 0 1 1 1 0 Tropomyosin FH2 PF02181.18 KUM56662.1 - 0.013 14.3 4.3 0.016 14.0 3.0 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain DUF2730 PF10805.3 KUM56662.1 - 0.064 13.0 4.8 2.9 7.6 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) TMF_TATA_bd PF12325.3 KUM56662.1 - 0.075 12.7 7.9 0.16 11.6 5.5 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF3393 PF11873.3 KUM56662.1 - 0.078 12.4 2.0 1.3 8.5 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3393) IncA PF04156.9 KUM56662.1 - 0.089 12.3 0.5 0.099 12.2 0.3 1.2 1 0 0 1 1 1 0 IncA protein TPR_MLP1_2 PF07926.7 KUM56662.1 - 0.091 12.5 8.6 0.15 11.7 6.0 1.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Ribosomal_L23 PF00276.15 KUM56662.1 - 0.12 12.3 2.7 0.15 11.9 0.1 2.0 2 0 0 2 2 2 0 Ribosomal protein L23 SYCE1 PF15233.1 KUM56662.1 - 0.14 12.1 6.7 0.18 11.7 4.6 1.2 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 Fib_alpha PF08702.5 KUM56662.1 - 0.15 12.1 5.7 0.24 11.5 4.0 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF3847 PF12958.2 KUM56662.1 - 0.22 11.3 8.8 0.42 10.3 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) SlyX PF04102.7 KUM56662.1 - 0.29 11.5 6.7 3.2 8.1 1.8 2.4 1 1 1 2 2 2 0 SlyX Snapin_Pallidin PF14712.1 KUM56662.1 - 0.35 11.2 6.8 0.58 10.5 4.7 1.4 1 0 0 1 1 1 0 Snapin/Pallidin GvpL_GvpF PF06386.6 KUM56662.1 - 0.44 10.1 3.7 0.58 9.7 2.5 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF COG2 PF06148.6 KUM56662.1 - 0.49 10.2 6.3 5.2 6.9 0.3 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TMF_DNA_bd PF12329.3 KUM56662.1 - 0.53 10.1 13.9 0.15 11.8 1.0 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF948 PF06103.6 KUM56662.1 - 0.68 9.8 6.7 1.6 8.6 1.0 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF342 PF03961.8 KUM56662.1 - 0.9 7.8 8.4 0.75 8.1 5.2 1.3 1 1 1 2 2 2 0 Protein of unknown function (DUF342) APG6 PF04111.7 KUM56662.1 - 1.2 8.1 8.8 2.9 6.8 5.6 1.6 1 1 0 1 1 1 0 Autophagy protein Apg6 FlaC_arch PF05377.6 KUM56662.1 - 1.2 9.0 4.4 18 5.2 0.1 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF904 PF06005.7 KUM56662.1 - 1.9 8.8 11.0 1 9.7 4.9 2.3 2 1 0 2 2 1 0 Protein of unknown function (DUF904) EMP24_GP25L PF01105.19 KUM56662.1 - 2.3 7.9 7.7 22 4.7 5.2 2.0 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF465 PF04325.8 KUM56662.1 - 2.9 7.6 8.1 0.064 12.9 0.9 1.9 2 1 0 2 2 1 0 Protein of unknown function (DUF465) Bap31 PF05529.7 KUM56662.1 - 3 7.2 8.7 4.3 6.7 5.5 1.6 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like DUF972 PF06156.8 KUM56662.1 - 3.4 8.0 9.2 4.1 7.7 5.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Ndufs5 PF10200.4 KUM56662.1 - 4.8 7.2 7.0 2.9 7.9 1.0 2.2 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF4337 PF14235.1 KUM56662.1 - 5.6 6.7 9.1 45 3.8 6.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) DivIC PF04977.10 KUM56662.1 - 6.1 6.3 8.1 7.6 6.0 1.8 2.4 1 1 1 2 2 2 0 Septum formation initiator Prenylcys_lyase PF07156.9 KUM56663.1 - 4e-37 127.9 0.0 1.2e-35 123.1 0.0 2.3 1 1 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 KUM56663.1 - 7e-13 48.3 0.0 1.5e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KUM56663.1 - 2.2e-08 33.6 0.0 1.9e-07 30.5 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 KUM56663.1 - 5.7e-06 25.4 0.3 0.0019 17.1 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KUM56663.1 - 7.4e-05 22.5 0.5 0.0028 17.4 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 KUM56663.1 - 0.02 15.2 0.2 8.7 6.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KUM56663.1 - 0.045 13.6 0.2 0.19 11.6 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KUM56663.1 - 0.047 12.1 0.1 0.78 8.1 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.1 KUM56663.1 - 0.054 13.5 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_3 PF07859.8 KUM56663.1 - 0.084 12.4 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Clp1 PF06807.9 KUM56664.1 - 7.4e-09 35.6 0.0 6.9e-08 32.4 0.0 2.2 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 AAA_17 PF13207.1 KUM56664.1 - 0.0014 19.4 0.0 0.011 16.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KUM56664.1 - 0.0023 17.8 0.2 0.014 15.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 KUM56664.1 - 0.0028 17.3 0.0 0.0086 15.7 0.0 1.8 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 KUM56664.1 - 0.035 13.5 0.0 0.073 12.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 KUM56664.1 - 0.048 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Adeno_IVa2 PF02456.10 KUM56664.1 - 0.13 10.8 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein RNA_polI_A34 PF08208.6 KUM56665.1 - 4.9e-38 130.7 24.7 4.9e-38 130.7 17.1 2.6 2 1 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 Prefoldin PF02996.12 KUM56667.1 - 3.9e-12 45.8 0.1 4.8e-12 45.5 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 KUM56667.1 - 0.0017 18.1 0.1 0.0022 17.7 0.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit HR1 PF02185.11 KUM56667.1 - 0.0052 16.5 0.1 0.0074 15.9 0.1 1.3 1 0 0 1 1 1 1 Hr1 repeat MAD PF05557.8 KUM56667.1 - 0.009 14.1 0.3 0.0092 14.1 0.2 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF4201 PF13870.1 KUM56667.1 - 0.023 14.1 0.1 0.024 14.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) S1-P1_nuclease PF02265.11 KUM56668.1 - 2.2e-70 237.1 0.1 2.5e-70 236.9 0.1 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Endotoxin_mid PF09131.5 KUM56668.1 - 0.056 12.8 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacillus thuringiensis delta-Endotoxin, middle domain NmrA PF05368.8 KUM56669.1 - 0.0005 19.3 0.0 0.0006 19.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family ETF PF01012.16 KUM56670.1 - 9.2e-42 142.5 0.5 1.7e-41 141.6 0.4 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 KUM56670.1 - 2.5e-34 116.7 0.1 5.1e-34 115.7 0.1 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain GST_C PF00043.20 KUM56671.1 - 1e-13 51.0 0.0 1.5e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KUM56671.1 - 5e-13 49.0 0.0 8.1e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KUM56671.1 - 5.7e-13 48.8 0.0 3.4e-12 46.3 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KUM56671.1 - 1.6e-11 44.0 0.1 3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KUM56671.1 - 1.2e-08 34.7 0.0 2.2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KUM56671.1 - 2.7e-07 30.9 0.0 4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 KUM56671.1 - 0.083 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 MetRS-N binding domain AAA PF00004.24 KUM56672.1 - 2.6e-11 43.8 0.0 8e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KUM56672.1 - 3.8e-06 27.0 0.0 9.4e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KUM56672.1 - 4.7e-05 23.1 0.0 0.00011 21.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KUM56672.1 - 5e-05 22.4 0.0 0.0001 21.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KUM56672.1 - 0.00011 21.8 0.0 0.00054 19.6 0.0 2.2 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KUM56672.1 - 0.0012 19.6 0.0 0.0045 17.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KUM56672.1 - 0.0017 18.2 0.0 0.0056 16.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KUM56672.1 - 0.0086 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 KUM56672.1 - 0.01 14.5 0.0 0.021 13.5 0.0 1.5 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 KUM56672.1 - 0.011 15.7 0.0 0.064 13.2 0.0 2.2 1 1 1 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 KUM56672.1 - 0.011 14.8 0.0 0.026 13.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DUF258 PF03193.11 KUM56672.1 - 0.015 14.5 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 KUM56672.1 - 0.034 13.5 0.0 0.069 12.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Ribosomal_L1 PF00687.16 KUM56673.1 - 5.1e-55 186.2 5.0 5.1e-55 186.2 3.4 1.6 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family PH_5 PF15405.1 KUM56673.1 - 0.067 13.1 0.1 0.067 13.1 0.1 2.4 3 0 0 3 3 3 0 Pleckstrin homology domain LolA PF03548.10 KUM56674.1 - 0.12 11.9 1.3 0.14 11.7 0.9 1.1 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA Mcm10 PF09332.6 KUM56674.1 - 1.4 8.1 5.0 1.6 7.9 3.5 1.0 1 0 0 1 1 1 0 Mcm10 replication factor SSP160 PF06933.6 KUM56674.1 - 4.8 5.0 13.4 5 4.9 9.3 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Phage_fiber PF03335.8 KUM56675.1 - 0.083 12.5 0.5 0.14 11.9 0.3 1.3 1 0 0 1 1 1 0 Phage tail fibre repeat DUF4621 PF15414.1 KUM56676.1 - 0.0029 16.3 0.0 0.0037 16.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4621) Ceramidase_alk PF04734.8 KUM56676.1 - 0.0062 14.4 0.0 0.0075 14.1 0.0 1.1 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Sec2p PF06428.6 KUM56676.1 - 0.11 12.3 0.9 0.3 10.9 0.6 1.7 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Snapin_Pallidin PF14712.1 KUM56676.1 - 0.33 11.2 3.7 0.24 11.7 1.2 1.7 2 0 0 2 2 2 0 Snapin/Pallidin DUF106 PF01956.11 KUM56677.1 - 0.46 9.9 5.7 5.5 6.4 0.1 2.5 2 1 0 2 2 2 0 Integral membrane protein DUF106 SHP PF03579.8 KUM56677.1 - 3.1 7.2 8.0 0.34 10.2 1.6 2.2 2 0 0 2 2 2 0 Small hydrophobic protein AA_permease_2 PF13520.1 KUM56678.1 - 3.2e-42 144.5 52.0 4.1e-42 144.2 36.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM56678.1 - 1.7e-16 59.6 45.9 2.6e-16 59.0 31.8 1.1 1 0 0 1 1 1 1 Amino acid permease SNF2_N PF00176.18 KUM56680.1 - 1.3e-63 214.5 0.0 2e-63 213.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KUM56680.1 - 5.9e-12 45.2 0.0 1.2e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KUM56680.1 - 1.9e-05 24.6 0.1 4.7e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 KUM56680.1 - 0.00054 18.8 0.0 0.0035 16.1 0.0 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ETRAMP PF09716.5 KUM56680.1 - 0.42 10.5 2.0 0.53 10.2 0.1 2.1 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) CVNH PF08881.5 KUM56681.1 - 2e-31 108.2 0.4 2.2e-31 108.1 0.3 1.0 1 0 0 1 1 1 1 CVNH domain PfkB PF00294.19 KUM56682.1 - 1.9e-32 112.6 0.0 3e-32 111.9 0.0 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase RNase_H PF00075.19 KUM56683.1 - 4e-06 27.1 0.1 5.5e-05 23.5 0.0 2.2 1 1 0 1 1 1 1 RNase H DUF3971 PF13116.1 KUM56683.1 - 0.049 13.0 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function Cwf_Cwc_15 PF04889.7 KUM56685.1 - 0.26 10.9 11.8 0.34 10.5 8.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNase_H PF00075.19 KUM56687.1 - 2.5e-05 24.6 0.0 6e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 RNase H OGFr_III PF04680.8 KUM56688.1 - 0.27 11.4 1.2 0.43 10.7 0.8 1.3 1 0 0 1 1 1 0 Opioid growth factor receptor repeat PEPcase PF00311.12 KUM56689.1 - 0.037 11.8 0.1 0.038 11.8 0.0 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase FA_desaturase PF00487.19 KUM56690.1 - 6.3e-24 84.8 15.0 7.6e-24 84.5 10.4 1.0 1 0 0 1 1 1 1 Fatty acid desaturase Glyco_hydro_3 PF00933.16 KUM56691.1 - 3.8e-47 160.7 0.0 4.6e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Cation_efflux PF01545.16 KUM56692.1 - 7.9e-39 133.4 0.1 8.6e-39 133.3 0.1 1.0 1 0 0 1 1 1 1 Cation efflux family DUF1929 PF09118.6 KUM56694.1 - 1.3e-26 92.5 0.1 2.1e-26 91.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 KUM56694.1 - 6.3e-05 22.6 0.3 0.00051 19.7 0.0 2.4 2 1 0 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.20 KUM56694.1 - 0.012 15.1 0.0 0.028 13.9 0.0 1.7 1 0 0 1 1 1 0 Kelch motif Kelch_6 PF13964.1 KUM56694.1 - 0.017 15.2 0.0 0.051 13.7 0.0 1.8 1 0 0 1 1 1 0 Kelch motif Glyoxal_oxid_N PF07250.6 KUM56694.1 - 0.032 13.3 0.0 0.055 12.5 0.0 1.4 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus CSTF_C PF14304.1 KUM56695.1 - 0.013 14.8 2.7 0.021 14.0 1.9 1.3 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal Abhydro_lipase PF04083.11 KUM56696.1 - 1.8e-20 72.0 0.0 3.7e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 KUM56696.1 - 2.6e-06 27.4 2.4 5.7e-06 26.3 1.7 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM56696.1 - 9.6e-05 22.1 0.0 0.00018 21.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM56696.1 - 0.025 14.1 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold MFS_1 PF07690.11 KUM56697.1 - 7.5e-38 130.1 53.4 3.1e-36 124.8 34.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1418 PF07214.7 KUM56697.1 - 0.022 14.3 0.0 0.17 11.5 0.0 2.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) Pirin PF02678.11 KUM56699.1 - 8e-24 83.5 1.0 2.7e-23 81.8 0.7 1.8 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.6 KUM56699.1 - 2.1e-06 27.1 1.8 0.00044 19.6 0.1 3.3 3 1 0 3 3 3 2 Cupin domain MelC1 PF06236.6 KUM56699.1 - 0.0057 16.6 0.1 0.015 15.2 0.1 1.7 1 1 0 1 1 1 1 Tyrosinase co-factor MelC1 Aa_trans PF01490.13 KUM56701.1 - 7.6e-44 149.8 24.6 8.7e-44 149.6 17.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 KUM56701.1 - 2.7e-05 22.8 36.9 5.8e-05 21.7 20.4 2.5 2 1 0 2 2 2 1 Amino acid permease DUF4134 PF13572.1 KUM56701.1 - 0.0034 17.4 5.3 0.034 14.2 0.1 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4134) Ycf4 PF02392.11 KUM56701.1 - 0.29 10.4 3.0 0.18 11.0 0.5 1.8 2 0 0 2 2 2 0 Ycf4 DUF605 PF04652.11 KUM56703.1 - 4.4 6.6 15.5 5.2 6.3 10.8 1.0 1 0 0 1 1 1 0 Vta1 like Vac7 PF12751.2 KUM56705.1 - 0.13 11.1 1.0 0.14 10.9 0.7 1.0 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Acyl_transf_1 PF00698.16 KUM56706.1 - 2.3e-21 76.4 1.4 3.3e-21 75.9 1.0 1.2 1 1 0 1 1 1 1 Acyl transferase domain DUF1370 PF07114.6 KUM56706.1 - 0.1 11.8 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1370) PS-DH PF14765.1 KUM56707.1 - 1.9e-54 184.8 0.3 3.3e-54 184.0 0.0 1.5 2 0 0 2 2 2 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KUM56707.1 - 2.1e-08 33.9 0.0 3.2e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Methyltransf_12 PF08242.7 KUM56707.1 - 2.4e-05 24.7 0.0 8e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM56707.1 - 0.0037 17.8 0.0 0.01 16.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM56707.1 - 0.043 13.5 0.0 0.38 10.4 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 KUM56707.1 - 0.051 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 KUM56707.1 - 0.064 12.2 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Cutinase PF01083.17 KUM56708.1 - 1.5e-51 174.6 2.4 1.8e-51 174.4 1.7 1.1 1 0 0 1 1 1 1 Cutinase VirJ PF06057.6 KUM56708.1 - 0.0007 19.4 0.0 0.0016 18.2 0.0 1.6 2 0 0 2 2 2 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.6 KUM56708.1 - 0.00086 18.7 0.1 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain Pec_lyase_C PF00544.14 KUM56709.1 - 5.5e-19 68.4 1.8 9e-19 67.7 1.3 1.4 1 0 0 1 1 1 1 Pectate lyase HD PF01966.17 KUM56710.1 - 8.7e-05 22.5 0.0 0.00026 21.0 0.0 1.8 1 1 0 1 1 1 1 HD domain Pec_lyase_C PF00544.14 KUM56711.1 - 1e-21 77.3 4.8 1.9e-21 76.4 3.3 1.4 1 0 0 1 1 1 1 Pectate lyase Tub_2 PF04525.7 KUM56712.1 - 3.9e-07 29.6 0.1 4.3e-06 26.2 0.1 2.3 1 1 0 1 1 1 1 Tubby C 2 PALP PF00291.20 KUM56713.1 - 1.9e-27 96.2 0.7 2.2e-27 96.0 0.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LYTB PF02401.13 KUM56713.1 - 0.033 13.0 0.0 0.06 12.2 0.0 1.3 1 0 0 1 1 1 0 LytB protein RTA1 PF04479.8 KUM56714.1 - 3.3e-58 196.8 5.4 5.6e-58 196.0 3.8 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF165 PF02592.10 KUM56714.1 - 0.2 11.8 4.0 1.9 8.6 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized ACR, YhhQ family COG1738 Kei1 PF08552.6 KUM56714.1 - 1.8 8.1 5.2 0.18 11.4 0.1 1.8 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 RTA1 PF04479.8 KUM56716.1 - 3.6e-57 193.4 11.0 3.6e-57 193.4 7.6 1.8 2 0 0 2 2 2 1 RTA1 like protein DUF4579 PF15158.1 KUM56716.1 - 0.34 10.4 2.3 0.28 10.6 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4579) HNH_2 PF13391.1 KUM56717.1 - 4e-07 29.7 0.0 8.7e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease GDPD PF03009.12 KUM56719.1 - 1.3e-09 37.9 0.0 2.1e-09 37.2 0.0 1.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 KUM56719.1 - 0.0032 17.6 0.1 0.0073 16.4 0.1 1.7 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family LIM PF00412.17 KUM56720.1 - 3.6e-18 65.3 15.2 8.3e-11 41.7 3.1 2.4 2 0 0 2 2 2 2 LIM domain Terminase_GpA PF05876.7 KUM56720.1 - 0.024 13.0 0.9 0.039 12.3 0.6 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Cytochrom_c3_2 PF14537.1 KUM56720.1 - 0.36 11.2 10.7 3.4 8.0 2.2 2.4 1 1 1 2 2 2 0 Cytochrome c3 Cytochrome_C7 PF14522.1 KUM56720.1 - 4.4 7.0 16.1 2.4 7.8 8.2 2.3 1 1 2 3 3 3 0 Cytochrome c7 Sugar_tr PF00083.19 KUM56721.1 - 3.5e-85 286.2 27.3 4.2e-85 286.0 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM56721.1 - 9e-22 77.2 31.5 9e-22 77.2 21.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily NAD_binding_5 PF07994.7 KUM56722.1 - 1.3e-110 369.5 0.1 1.6e-110 369.2 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 KUM56722.1 - 2.5e-46 156.0 0.6 5.6e-46 154.9 0.4 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DUF1459 PF07312.6 KUM56722.1 - 0.043 13.7 0.1 0.21 11.5 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1459) Fungal_trans_2 PF11951.3 KUM56723.1 - 8.1e-10 37.8 0.0 1.1e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM56723.1 - 1.2e-05 25.1 14.0 2.3e-05 24.2 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GDPD PF03009.12 KUM56724.1 - 1.6e-14 54.0 0.1 2e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DNA_ligase_A_M PF01068.16 KUM56727.1 - 1.4e-46 158.4 0.1 6.3e-46 156.2 0.0 2.2 2 1 1 3 3 3 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KUM56727.1 - 7e-41 139.9 0.0 3.1e-40 137.8 0.0 2.1 3 0 0 3 3 3 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KUM56727.1 - 8.7e-19 67.7 0.3 6.1e-18 65.0 0.0 2.7 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 KUM56727.1 - 3.3e-09 36.7 0.0 5.2e-05 23.3 0.0 2.9 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.3 KUM56727.1 - 1.9e-05 24.3 0.1 4.2e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 DNA ligase IV mRNA_cap_enzyme PF01331.14 KUM56727.1 - 0.004 16.8 0.1 0.13 11.9 0.0 3.0 2 2 0 2 2 2 1 mRNA capping enzyme, catalytic domain RNA_ligase PF09414.5 KUM56727.1 - 0.0041 16.9 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 RNA ligase BTB PF00651.26 KUM56728.1 - 0.00085 19.2 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain FAP PF07174.6 KUM56728.1 - 0.0022 17.3 1.5 0.0038 16.5 1.0 1.4 1 0 0 1 1 1 1 Fibronectin-attachment protein (FAP) MCPVI PF02993.9 KUM56728.1 - 0.92 9.6 14.1 1.4 9.0 9.8 1.2 1 0 0 1 1 1 0 Minor capsid protein VI MFS_1 PF07690.11 KUM56730.1 - 1.5e-15 56.8 5.6 2e-15 56.3 3.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM56730.1 - 0.0023 16.5 0.8 0.0028 16.3 0.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter CRAL_TRIO PF00650.15 KUM56731.1 - 2e-41 141.1 0.0 4.5e-41 139.9 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KUM56731.1 - 3.7e-14 52.5 0.0 8.8e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KUM56731.1 - 9.1e-09 35.3 0.0 1.6e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Fungal_trans PF04082.13 KUM56732.1 - 2.8e-14 52.6 1.6 4.5e-14 51.9 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM56732.1 - 1.8e-08 34.1 10.3 3.6e-08 33.1 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KUM56733.1 - 1.3e-42 145.7 42.8 1.3e-42 145.7 29.6 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM56733.1 - 9.4e-08 30.6 19.9 1.3e-07 30.1 13.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RnfC_N PF13375.1 KUM56733.1 - 0.05 13.3 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Flavi_NS2A PF01005.14 KUM56734.1 - 0.015 14.6 0.0 0.018 14.3 0.0 1.0 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2A adh_short PF00106.20 KUM56737.1 - 1.6e-15 57.3 0.1 2.6e-15 56.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM56737.1 - 1.2e-09 38.3 0.1 1.7e-09 37.8 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KUM56737.1 - 8.2e-08 31.9 0.1 3.9e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KUM56737.1 - 1.8e-06 27.7 0.0 3.6e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KUM56737.1 - 0.017 15.1 0.1 0.18 11.8 0.1 2.0 1 1 0 1 1 1 0 NADH(P)-binding DAO PF01266.19 KUM56738.1 - 1.8e-10 40.2 6.3 0.0001 21.3 0.1 3.0 1 1 2 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KUM56738.1 - 2.6e-07 30.0 0.4 4.6e-07 29.2 0.2 1.4 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 KUM56738.1 - 4.1e-06 25.9 1.0 0.00013 20.9 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KUM56738.1 - 0.0002 19.9 0.2 0.051 12.0 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.2 KUM56738.1 - 0.0013 17.8 0.7 0.0034 16.5 0.5 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KUM56738.1 - 0.0028 17.6 0.1 0.006 16.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KUM56738.1 - 0.0046 15.6 0.6 1.3 7.5 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.9 KUM56738.1 - 0.0058 16.5 0.4 0.022 14.6 0.3 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KUM56738.1 - 0.0061 16.6 0.4 0.028 14.5 0.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KUM56738.1 - 0.01 14.9 0.1 0.58 9.2 0.0 2.1 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 KUM56738.1 - 0.011 14.6 0.5 0.11 11.3 0.2 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KUM56738.1 - 0.024 13.5 0.9 0.073 11.9 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.22 KUM56738.1 - 0.063 13.6 0.4 9 6.7 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Porin_3 PF01459.17 KUM56739.1 - 1.5e-78 263.9 0.0 1.7e-78 263.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.5 KUM56739.1 - 0.033 13.5 0.0 0.078 12.3 0.0 1.5 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term Pkinase PF00069.20 KUM56740.1 - 8.3e-65 218.5 0.0 9.8e-65 218.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM56740.1 - 4.2e-25 88.2 0.0 5.3e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM56740.1 - 1e-06 27.9 0.0 4.5e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KUM56740.1 - 0.00067 19.4 0.1 0.019 14.6 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family rpo132 PF12415.3 KUM56740.1 - 0.029 13.3 0.7 0.91 8.5 0.0 2.6 2 0 0 2 2 2 0 Poxvirus DNA dependent RNA polymerase Choline_kinase PF01633.15 KUM56740.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase MIF4G_like PF09088.6 KUM56741.1 - 5.2e-81 270.6 0.1 8.6e-81 269.9 0.1 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 KUM56741.1 - 7.4e-60 202.2 0.0 1.2e-59 201.6 0.0 1.3 1 0 0 1 1 1 1 MIF4G like zf-C2H2 PF00096.21 KUM56742.1 - 1e-19 69.6 20.5 5.8e-05 23.1 0.6 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KUM56742.1 - 2.1e-18 65.5 17.9 1.6e-08 34.4 1.7 4.8 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 KUM56742.1 - 3.3e-15 55.2 18.8 0.0019 18.3 0.2 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 KUM56742.1 - 0.0014 18.7 8.0 0.15 12.3 0.1 4.9 4 0 0 4 4 4 1 Zinc-finger of C2H2 type Ogr_Delta PF04606.7 KUM56742.1 - 0.041 13.5 5.7 2.2 8.0 0.0 3.3 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger CHORD PF04968.7 KUM56742.1 - 3.9 7.8 11.9 14 5.9 1.1 3.4 2 1 1 3 3 3 0 CHORD 6PF2K PF01591.13 KUM56743.1 - 2.9e-63 212.9 0.1 4.3e-63 212.3 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KUM56743.1 - 3e-22 79.4 1.0 5e-22 78.6 0.7 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 KUM56743.1 - 9.9e-06 26.3 0.3 0.00022 22.0 0.2 2.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KUM56743.1 - 0.00048 20.0 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KUM56743.1 - 0.0035 16.5 0.0 0.0062 15.7 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 APS_kinase PF01583.15 KUM56743.1 - 0.05 13.2 0.0 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase Urm1 PF09138.6 KUM56744.1 - 9.5e-28 96.1 0.0 1.7e-27 95.3 0.0 1.4 1 1 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 KUM56744.1 - 0.0033 17.8 0.0 0.0041 17.5 0.0 1.4 1 1 0 1 1 1 1 ThiS family WD40 PF00400.27 KUM56745.1 - 1.3e-62 205.5 24.2 3.6e-09 36.1 0.0 12.2 12 0 0 12 12 12 10 WD domain, G-beta repeat BBS2_Mid PF14783.1 KUM56745.1 - 0.0004 20.1 0.1 4.7 7.0 0.0 5.3 6 1 0 6 6 6 2 Ciliary BBSome complex subunit 2, middle region 3HCDH_N PF02737.13 KUM56747.1 - 2.7e-28 98.8 0.0 1.6e-27 96.3 0.0 2.0 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KUM56747.1 - 8.2e-12 45.3 0.0 1.5e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain SGL PF08450.7 KUM56747.1 - 0.0012 18.2 0.1 0.094 12.0 0.0 3.0 1 1 1 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Pyr_redox PF00070.22 KUM56747.1 - 0.003 17.9 0.2 0.015 15.6 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Arylesterase PF01731.15 KUM56747.1 - 0.0097 15.8 0.0 7.1 6.7 0.0 2.8 2 0 0 2 2 2 2 Arylesterase NHL PF01436.16 KUM56747.1 - 0.02 14.8 0.4 2.7 8.1 0.0 3.9 4 0 0 4 4 4 0 NHL repeat NAD_binding_2 PF03446.10 KUM56747.1 - 0.046 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ldl_recept_b PF00058.12 KUM56747.1 - 0.086 13.1 0.1 11 6.4 0.0 3.8 4 0 0 4 4 4 0 Low-density lipoprotein receptor repeat class B Str_synth PF03088.11 KUM56747.1 - 0.1 12.6 0.0 0.5 10.4 0.0 2.1 2 0 0 2 2 2 0 Strictosidine synthase MFS_1 PF07690.11 KUM56748.1 - 2.5e-30 105.4 24.6 3.1e-30 105.0 17.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily GMC_oxred_N PF00732.14 KUM56751.1 - 7.1e-54 182.9 0.0 9.4e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KUM56751.1 - 1e-32 113.4 0.2 1.9e-32 112.5 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KUM56751.1 - 0.00012 21.1 0.0 0.28 10.0 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KUM56751.1 - 0.00057 18.9 0.0 0.00094 18.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KUM56751.1 - 0.0025 17.8 0.0 0.0061 16.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KUM56751.1 - 0.0054 15.6 0.0 0.47 9.2 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.9 KUM56751.1 - 0.053 11.9 0.0 0.63 8.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.1 KUM56751.1 - 0.1 12.6 0.0 3 7.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Metallophos PF00149.23 KUM56753.1 - 2e-18 66.5 0.1 4.4e-18 65.3 0.1 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 KUM56753.1 - 3.6e-15 55.7 0.0 8.1e-15 54.6 0.0 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 KUM56753.1 - 1.9e-09 36.6 0.2 9.7e-09 34.2 0.1 1.8 2 0 0 2 2 2 1 PhoD-like phosphatase Metallophos_2 PF12850.2 KUM56753.1 - 0.0053 16.6 0.0 0.012 15.4 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain fn3 PF00041.16 KUM56753.1 - 0.084 13.0 2.1 0.16 12.1 1.5 1.4 1 0 0 1 1 1 0 Fibronectin type III domain PhzC-PhzF PF02567.11 KUM56754.1 - 7.8e-42 143.4 0.0 8.9e-42 143.2 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Amidase PF01425.16 KUM56755.1 - 3.1e-33 115.3 2.5 3.2e-33 115.2 0.9 1.6 2 0 0 2 2 2 1 Amidase DAO PF01266.19 KUM56756.1 - 8.2e-31 107.1 0.0 1.2e-30 106.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KUM56756.1 - 5.3e-07 29.9 0.0 6.7e-06 26.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM56756.1 - 7.2e-07 29.1 0.0 2.3e-06 27.5 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KUM56756.1 - 2.6e-06 27.4 0.0 7.5e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.10 KUM56756.1 - 0.00015 21.6 0.0 0.0012 18.7 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 KUM56756.1 - 0.0003 20.5 0.0 0.001 18.7 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 KUM56756.1 - 0.0011 18.6 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 KUM56756.1 - 0.0013 18.7 0.0 0.042 13.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM56756.1 - 0.0019 17.9 0.1 0.07 12.9 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding ApbA PF02558.11 KUM56756.1 - 0.016 14.6 0.0 0.057 12.8 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 KUM56756.1 - 0.019 14.9 0.0 0.35 10.8 0.0 2.3 2 0 0 2 2 2 0 NADH(P)-binding TrkA_N PF02254.13 KUM56756.1 - 0.024 14.6 0.1 0.056 13.4 0.0 1.7 2 0 0 2 2 1 0 TrkA-N domain FAD_binding_2 PF00890.19 KUM56756.1 - 0.025 13.4 0.0 0.04 12.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 KUM56756.1 - 0.029 13.7 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 KUM56756.1 - 0.051 12.0 0.0 0.083 11.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein F420_oxidored PF03807.12 KUM56756.1 - 0.08 13.3 0.0 3.9 7.9 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 KUM56756.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain FAD_binding_3 PF01494.14 KUM56756.1 - 0.18 10.8 0.0 0.35 9.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.19 KUM56757.1 - 4e-27 95.3 0.6 2e-26 93.0 0.4 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KUM56757.1 - 1.2e-06 28.4 0.0 3.1e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KUM56757.1 - 0.00043 20.3 0.0 0.0012 18.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KUM56757.1 - 0.02 13.9 0.2 0.036 13.1 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 KUM56757.1 - 0.041 14.2 0.2 0.11 12.8 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 KUM56758.1 - 1.1e-14 54.7 0.3 1.4e-14 54.3 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM56758.1 - 1.7e-08 34.5 0.0 2.2e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM56758.1 - 1.9e-06 27.6 0.2 2.8e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM56758.1 - 0.0015 18.0 0.0 0.0037 16.7 0.0 1.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KUM56758.1 - 0.014 15.4 1.4 0.14 12.1 1.0 2.3 1 1 0 1 1 1 0 NADH(P)-binding DUF1776 PF08643.5 KUM56758.1 - 0.085 11.9 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Pyr_redox_2 PF07992.9 KUM56759.1 - 7.8e-09 35.6 0.0 8.2e-08 32.3 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KUM56759.1 - 2.8e-08 34.0 0.0 0.00078 19.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM56759.1 - 0.00059 19.8 0.0 0.0016 18.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KUM56759.1 - 0.015 13.7 0.0 0.025 13.0 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 KUM56759.1 - 0.016 14.9 0.1 0.047 13.4 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 KUM56759.1 - 0.04 14.1 0.0 3.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.19 KUM56759.1 - 0.08 11.7 0.1 0.46 9.2 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain DUF1880 PF08976.6 KUM56759.1 - 0.11 12.6 0.1 0.28 11.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) K_oxygenase PF13434.1 KUM56759.1 - 0.18 10.6 0.0 1.4 7.7 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 KUM56759.1 - 0.21 10.6 0.0 0.52 9.3 0.0 1.6 2 0 0 2 2 2 0 Thi4 family YwiC PF14256.1 KUM56760.1 - 0.13 12.3 3.5 0.096 12.7 1.3 1.6 1 1 0 1 1 1 0 YwiC-like protein PMAIP1 PF15150.1 KUM56761.1 - 0.0066 16.1 0.5 0.0088 15.7 0.3 1.1 1 0 0 1 1 1 1 Phorbol-12-myristate-13-acetate-induced Cerato-platanin PF07249.7 KUM56762.1 - 2.1e-46 156.7 0.6 2.5e-46 156.5 0.4 1.1 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.12 KUM56762.1 - 0.093 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Barwin family VP_N-CPKC PF11475.3 KUM56762.1 - 0.22 11.1 1.0 0.44 10.1 0.7 1.4 1 0 0 1 1 1 0 Virion protein N terminal domain Cytochrom_B561 PF03188.11 KUM56763.1 - 7.5e-07 29.0 13.5 1.5e-06 28.0 9.3 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.12 KUM56763.1 - 0.0012 18.7 0.2 0.0024 17.7 0.2 1.5 1 0 0 1 1 1 1 DOMON domain SdpI PF13630.1 KUM56763.1 - 0.0084 15.8 7.0 0.0084 15.8 4.8 2.8 2 1 1 3 3 3 1 SdpI/YhfL protein family DUF2427 PF10348.4 KUM56763.1 - 0.009 15.5 5.6 0.009 15.5 3.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) Abhydrolase_3 PF07859.8 KUM56764.1 - 7.9e-41 139.9 0.0 1.3e-33 116.4 0.0 2.7 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KUM56764.1 - 3.2e-14 52.3 0.0 5e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KUM56764.1 - 0.00014 21.6 0.0 0.00027 20.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KUM56764.1 - 0.00024 21.0 0.1 0.00049 20.0 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KUM56764.1 - 0.01 14.5 0.8 0.07 11.8 0.6 1.9 1 1 0 1 1 1 0 Carboxylesterase family Pyr_redox_3 PF13738.1 KUM56765.1 - 1.2e-07 31.9 0.1 3.6e-07 30.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KUM56765.1 - 0.003 16.5 0.0 1.3 7.8 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 KUM56765.1 - 0.023 12.9 0.2 0.36 8.9 0.0 2.3 2 1 1 3 3 3 0 Flavin-binding monooxygenase-like SLAC1 PF03595.12 KUM56766.1 - 3.1e-64 216.7 44.3 3.4e-64 216.5 30.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Adeno_E3 PF06040.6 KUM56766.1 - 0.039 13.9 1.9 5.8 6.8 0.0 3.0 3 0 0 3 3 3 0 Adenovirus E3 protein Glyco_transf_15 PF01793.11 KUM56767.1 - 1.2e-140 468.2 10.9 1.5e-140 467.9 7.6 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase UMP1 PF05348.6 KUM56769.1 - 3.7e-20 72.1 0.0 4.9e-20 71.8 0.0 1.3 1 1 0 1 1 1 1 Proteasome maturation factor UMP1 Rad60-SLD_2 PF13881.1 KUM56770.1 - 4.6e-12 45.8 0.2 1e-11 44.6 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KUM56770.1 - 0.0003 20.1 0.0 0.00079 18.7 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family DUF2407 PF10302.4 KUM56770.1 - 0.0069 16.5 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain GHMP_kinases_N PF00288.21 KUM56771.1 - 6.4e-14 51.7 1.7 1.6e-13 50.5 1.2 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KUM56771.1 - 1.3e-08 34.8 0.0 1.3e-07 31.7 0.0 2.4 2 1 0 2 2 2 1 GHMP kinases C terminal VGCC_beta4Aa_N PF12052.3 KUM56771.1 - 0.14 12.0 0.5 0.31 10.9 0.3 1.4 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Methyltransf_11 PF08241.7 KUM56772.1 - 3.8e-22 78.5 0.0 8.7e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM56772.1 - 6.5e-17 61.7 0.0 1.7e-16 60.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM56772.1 - 9e-17 61.0 0.0 2.7e-16 59.5 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM56772.1 - 2.8e-14 53.3 0.0 8.8e-14 51.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM56772.1 - 2.5e-12 47.1 0.0 5.4e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KUM56772.1 - 4.5e-12 45.5 0.0 5.3e-11 42.0 0.0 2.0 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KUM56772.1 - 7.3e-11 41.6 0.0 1e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 KUM56772.1 - 5.4e-10 39.8 0.0 1.3e-09 38.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KUM56772.1 - 6.2e-09 35.9 0.0 2.1e-08 34.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KUM56772.1 - 2.1e-06 27.2 0.0 3.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 KUM56772.1 - 3.8e-06 26.3 0.0 6.5e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.15 KUM56772.1 - 0.00024 20.2 0.0 0.00038 19.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TehB PF03848.9 KUM56772.1 - 0.0011 18.1 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.12 KUM56772.1 - 0.0015 17.6 0.0 0.0026 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 KUM56772.1 - 0.0023 17.1 0.0 0.0036 16.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.6 KUM56772.1 - 0.0034 16.1 0.1 0.032 12.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_8 PF05148.10 KUM56772.1 - 0.0043 16.7 0.0 0.044 13.4 0.0 2.1 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_32 PF13679.1 KUM56772.1 - 0.0052 16.4 0.0 0.0095 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KUM56772.1 - 0.0062 15.7 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase FmrO PF07091.6 KUM56772.1 - 0.0064 15.5 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) PCMT PF01135.14 KUM56772.1 - 0.0092 15.5 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.8 KUM56772.1 - 0.16 11.2 0.0 0.32 10.2 0.0 1.6 1 0 0 1 1 1 0 Histone methylation protein DOT1 Vps54 PF07928.7 KUM56775.1 - 1.3e-48 164.5 0.8 6.7e-48 162.2 0.1 2.3 2 0 0 2 2 2 1 Vps54-like protein DUF2450 PF10475.4 KUM56775.1 - 8.2e-06 24.9 0.3 2.4e-05 23.3 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF2451 PF10474.4 KUM56775.1 - 0.0015 18.3 0.1 0.0032 17.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) LUC7 PF03194.10 KUM56775.1 - 0.0087 15.6 0.2 0.057 12.9 0.4 2.2 2 0 0 2 2 2 1 LUC7 N_terminus Pyr_redox_3 PF13738.1 KUM56776.1 - 2.7e-19 70.0 0.1 6e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KUM56776.1 - 5.2e-16 57.9 0.7 2.6e-15 55.6 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KUM56776.1 - 4.6e-10 39.3 0.0 1.1e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KUM56776.1 - 3e-08 32.9 0.2 5.9e-06 25.4 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KUM56776.1 - 0.00041 20.1 0.3 0.044 13.5 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 KUM56776.1 - 0.0013 17.7 0.0 0.16 10.8 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KUM56776.1 - 0.014 15.3 0.0 0.056 13.3 0.0 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 KUM56776.1 - 0.017 13.3 0.1 0.39 8.8 0.0 2.2 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.12 KUM56776.1 - 0.035 13.2 0.1 0.1 11.6 0.0 1.7 2 0 0 2 2 2 0 Thi4 family ATP-grasp_4 PF13535.1 KUM56777.1 - 6.4e-22 78.1 0.0 3e-18 66.2 0.0 3.0 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KUM56777.1 - 1.3e-07 31.2 0.0 2.3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.12 KUM56777.1 - 5e-06 25.9 0.0 3.6e-05 23.1 0.0 2.2 3 0 0 3 3 3 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 KUM56777.1 - 0.00027 20.4 0.0 0.0006 19.3 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KUM56777.1 - 0.001 18.9 0.0 0.021 14.6 0.0 2.5 2 1 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 KUM56777.1 - 0.0018 17.8 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_Ter PF15632.1 KUM56777.1 - 0.0025 16.6 0.0 0.054 12.2 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon MCM PF00493.18 KUM56778.1 - 7.4e-142 472.0 0.1 9.6e-142 471.6 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KUM56778.1 - 1.1e-18 67.9 0.6 3.1e-18 66.4 0.1 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KUM56778.1 - 3.8e-06 26.2 0.0 0.0009 18.4 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KUM56778.1 - 5.7e-05 22.8 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KUM56778.1 - 0.00075 19.1 0.0 0.0026 17.3 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 KUM56778.1 - 0.0065 16.8 0.3 0.019 15.3 0.2 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KUM56778.1 - 0.049 13.1 0.0 1.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain PTR2 PF00854.16 KUM56781.1 - 1.9e-29 102.6 13.3 9e-17 60.9 1.9 2.4 1 1 1 2 2 2 2 POT family 2TM PF13239.1 KUM56781.1 - 2.7 8.0 4.8 0.79 9.8 0.1 2.5 3 0 0 3 3 3 0 2TM domain DUF4231 PF14015.1 KUM56781.1 - 2.8 7.9 6.8 0.31 11.0 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) IstB_IS21 PF01695.12 KUM56782.1 - 0.093 12.1 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein bZIP_1 PF00170.16 KUM56783.1 - 9.7e-05 22.2 8.6 0.0002 21.2 6.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor DUF4407 PF14362.1 KUM56783.1 - 0.027 13.4 2.3 0.93 8.3 2.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) bZIP_2 PF07716.10 KUM56783.1 - 0.037 13.8 11.0 0.028 14.2 6.1 1.9 2 0 0 2 2 2 0 Basic region leucine zipper Fib_alpha PF08702.5 KUM56783.1 - 0.22 11.6 1.7 0.34 11.0 1.2 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family GvpL_GvpF PF06386.6 KUM56783.1 - 0.46 10.0 3.6 0.74 9.3 2.5 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF1180 PF06679.7 KUM56784.1 - 0.24 11.2 2.3 0.37 10.6 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) HCO3_cotransp PF00955.16 KUM56785.1 - 3.2e-70 237.2 11.8 1.4e-41 142.7 2.8 2.0 1 1 1 2 2 2 2 HCO3- transporter family DEAD PF00270.24 KUM56786.1 - 2.4e-41 141.0 0.0 3.7e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM56786.1 - 3.1e-27 94.2 0.1 7.6e-27 92.9 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KUM56786.1 - 7.1e-05 21.7 0.0 0.00011 21.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KUM56786.1 - 0.00021 21.1 0.0 0.00065 19.5 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Stm1_N PF09598.5 KUM56787.1 - 1.8e-15 57.3 4.6 1.8e-15 57.3 3.2 5.6 3 1 1 4 4 4 1 Stm1 NAD_binding_10 PF13460.1 KUM56788.1 - 1.9e-15 57.3 0.3 2.9e-15 56.7 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KUM56788.1 - 2e-13 50.3 0.9 1e-12 48.0 0.6 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KUM56788.1 - 6.3e-10 38.7 0.6 1e-09 38.0 0.4 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 KUM56788.1 - 7e-07 28.4 0.0 9.1e-06 24.7 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 KUM56788.1 - 5.2e-06 25.3 0.3 1.8e-05 23.6 0.2 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KUM56788.1 - 2.2e-05 24.4 0.3 7e-05 22.8 0.1 1.9 2 0 0 2 2 2 1 TrkA-N domain adh_short PF00106.20 KUM56788.1 - 9.7e-05 22.3 0.7 0.0002 21.3 0.5 1.6 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KUM56788.1 - 0.00025 20.0 0.4 0.00072 18.5 0.2 1.8 2 0 0 2 2 2 1 Male sterility protein Saccharop_dh PF03435.13 KUM56788.1 - 0.0056 15.7 0.2 0.0084 15.1 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 KUM56788.1 - 0.025 14.9 0.1 0.058 13.8 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.15 KUM56788.1 - 0.033 14.1 1.6 0.13 12.2 0.7 2.4 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus mRNA_triPase PF02940.10 KUM56789.1 - 0.093 12.4 1.8 0.15 11.8 1.3 1.3 1 0 0 1 1 1 0 mRNA capping enzyme, beta chain DUF1793 PF08760.6 KUM56790.1 - 1.5e-73 246.2 2.0 2.9e-73 245.3 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) adh_short PF00106.20 KUM56791.1 - 6e-19 68.5 0.0 7.7e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM56791.1 - 8.6e-09 35.5 0.0 1.1e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM56791.1 - 1.8e-06 27.7 0.0 2.7e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM56791.1 - 0.00026 20.4 0.1 0.001 18.5 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KUM56791.1 - 0.00037 19.8 0.0 0.0013 18.0 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 KUM56791.1 - 0.00048 20.1 0.1 0.0029 17.6 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding His_biosynth PF00977.16 KUM56791.1 - 0.056 12.7 0.0 0.083 12.1 0.0 1.2 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF3353 PF11833.3 KUM56792.1 - 0.054 12.9 1.1 0.11 11.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) Tri3 PF07428.6 KUM56793.1 - 0.00014 20.7 0.0 0.072 11.7 0.0 2.9 2 1 1 3 3 3 2 15-O-acetyltransferase Tri3 Acyl_transf_1 PF00698.16 KUM56794.1 - 1.6e-54 185.4 0.0 3.9e-54 184.1 0.0 1.7 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KUM56794.1 - 1.8e-54 184.1 0.0 4.2e-54 182.9 0.0 1.6 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 KUM56794.1 - 4.8e-52 176.9 0.2 9.2e-52 176.0 0.2 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KUM56794.1 - 4.7e-42 143.7 0.0 1.6e-41 142.0 0.0 2.0 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KUM56794.1 - 2.1e-29 101.7 0.1 5.1e-29 100.5 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KUM56794.1 - 1.8e-18 66.3 0.2 1.9e-17 63.0 0.0 2.7 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM56794.1 - 1.1e-06 28.2 0.2 2.6e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KUM56794.1 - 2.9e-06 27.4 0.4 7.6e-06 26.0 0.3 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.1 KUM56794.1 - 4.6e-05 24.3 0.0 0.00025 21.9 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 3Beta_HSD PF01073.14 KUM56794.1 - 0.035 12.8 0.0 0.073 11.7 0.0 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Myosin_TH1 PF06017.8 KUM56794.1 - 0.24 10.6 0.1 0.42 9.8 0.1 1.3 1 0 0 1 1 1 0 Myosin tail ketoacyl-synt PF00109.21 KUM56795.1 - 2.9e-72 243.1 0.0 3.4e-72 242.9 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain DNA_gyraseB_C PF00986.16 KUM56795.1 - 0.027 14.2 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus Thiolase_N PF00108.18 KUM56795.1 - 0.05 12.5 0.1 0.079 11.9 0.1 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain ACP_syn_III PF08545.5 KUM56795.1 - 0.14 11.8 2.1 0.36 10.5 1.4 1.8 1 1 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III adh_short PF00106.20 KUM56797.1 - 1.4e-22 80.3 5.8 2.1e-22 79.8 4.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM56797.1 - 6.4e-20 71.9 0.3 7.7e-20 71.6 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM56797.1 - 9.6e-13 48.1 5.5 7.9e-12 45.2 3.8 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM56797.1 - 0.0035 16.7 0.2 0.83 9.0 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KUM56797.1 - 0.0059 15.6 0.3 0.008 15.1 0.2 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Eno-Rase_NADH_b PF12242.3 KUM56797.1 - 0.022 14.5 1.8 0.48 10.2 0.8 2.5 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ThiF PF00899.16 KUM56797.1 - 0.18 11.6 2.2 0.41 10.4 1.5 1.7 1 1 0 1 1 1 0 ThiF family Zn_clus PF00172.13 KUM56799.1 - 0.0033 17.3 4.7 0.0083 16.0 3.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-BED PF02892.10 KUM56799.1 - 0.0046 16.6 0.3 0.0046 16.6 0.2 1.8 2 0 0 2 2 2 1 BED zinc finger zf-C2H2_6 PF13912.1 KUM56799.1 - 0.026 14.4 2.5 0.25 11.3 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger CPL PF08144.6 KUM56800.1 - 7.8e-16 58.2 0.1 4.4e-15 55.7 0.0 2.4 3 0 0 3 3 3 1 CPL (NUC119) domain Bt_P21 PF05560.6 KUM56800.1 - 0.0046 16.3 0.0 0.012 14.9 0.0 1.7 1 0 0 1 1 1 1 Bacillus thuringiensis P21 molecular chaperone protein Daxx PF03344.10 KUM56800.1 - 0.0071 14.9 25.7 0.013 14.0 17.8 1.3 1 0 0 1 1 1 1 Daxx Family Pex14_N PF04695.8 KUM56800.1 - 3.5 7.6 12.7 1.3 9.0 1.3 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ndc1_Nup PF09531.5 KUM56800.1 - 7.1 4.9 12.0 12 4.1 8.3 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4220 PF13968.1 KUM56800.1 - 9.7 5.1 7.7 7.1 5.6 0.3 2.6 2 1 1 4 4 4 0 Domain of unknown function (DUF4220) KCNQC3-Ank-G_bd PF11956.3 KUM56801.1 - 1.7 8.7 4.7 0.98 9.5 0.8 2.2 1 1 2 3 3 3 0 Ankyrin-G binding motif of KCNQ2-3 ATP-synt_10 PF05176.9 KUM56802.1 - 1.5e-89 299.5 0.0 2e-89 299.2 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein DNA_pol_B_palm PF14792.1 KUM56803.1 - 1.2e-31 109.1 0.0 2.3e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 KUM56803.1 - 5.5e-21 74.0 0.0 1.1e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 KUM56803.1 - 1.5e-18 66.6 0.4 3.1e-18 65.7 0.3 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 KUM56803.1 - 5.2e-16 57.9 0.3 1.5e-15 56.4 0.0 2.0 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda BRCT PF00533.21 KUM56803.1 - 0.0072 16.4 0.0 0.023 14.8 0.0 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain NTP_transf_2 PF01909.18 KUM56803.1 - 0.039 14.2 0.0 0.09 13.1 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain HHH PF00633.18 KUM56803.1 - 0.068 12.9 0.2 0.18 11.5 0.1 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif V-SNARE_C PF12352.3 KUM56804.1 - 2.1e-12 46.9 0.8 1.1e-11 44.6 0.0 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus IncA PF04156.9 KUM56804.1 - 0.019 14.5 4.3 0.029 13.9 3.0 1.4 1 0 0 1 1 1 0 IncA protein Sec20 PF03908.8 KUM56804.1 - 0.051 13.2 0.7 1.3 8.7 0.0 2.9 3 1 0 3 3 3 0 Sec20 CorA PF01544.13 KUM56804.1 - 0.088 11.8 2.6 0.15 11.0 1.8 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Syntaxin-6_N PF09177.6 KUM56804.1 - 0.17 12.3 3.6 0.2 12.0 1.1 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal SpaB_C PF14028.1 KUM56804.1 - 0.55 9.7 5.4 7.5 6.0 0.1 2.1 1 1 1 2 2 2 0 SpaB C-terminal domain CENP-H PF05837.7 KUM56804.1 - 6.6 6.9 7.8 3.9 7.6 3.8 1.8 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Med16 PF11635.3 KUM56805.1 - 0.0094 13.9 0.0 0.065 11.1 0.0 1.9 1 1 1 2 2 2 2 Mediator complex subunit 16 Med16 PF11635.3 KUM56806.1 - 7.8e-45 153.1 0.0 9.3e-45 152.8 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 Hema_HEFG PF02710.9 KUM56806.1 - 0.027 14.7 0.0 0.045 14.0 0.0 1.3 1 0 0 1 1 1 0 Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein Ribosomal_L29 PF00831.18 KUM56807.1 - 4.1e-18 64.8 0.6 4.1e-18 64.8 0.4 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein CorA PF01544.13 KUM56807.1 - 0.02 13.9 3.1 0.024 13.6 2.1 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Cortex-I_coil PF09304.5 KUM56807.1 - 0.37 10.8 8.4 0.11 12.6 2.5 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF3585 PF12130.3 KUM56807.1 - 1 9.2 5.4 1.4 8.8 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3585) Snapin_Pallidin PF14712.1 KUM56807.1 - 3.3 8.1 6.8 0.46 10.8 1.2 1.9 1 1 1 2 2 2 0 Snapin/Pallidin Med16 PF11635.3 KUM56808.1 - 0.037 11.9 0.0 0.037 11.9 0.0 1.0 1 0 0 1 1 1 0 Mediator complex subunit 16 Med16 PF11635.3 KUM56809.1 - 3.1e-83 280.0 0.0 3.5e-83 279.8 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 DUF3336 PF11815.3 KUM56810.1 - 1.8e-51 173.4 4.3 2.8e-51 172.8 3.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KUM56810.1 - 3.5e-19 69.5 0.3 1.4e-18 67.5 0.0 2.2 3 1 0 3 3 3 1 Patatin-like phospholipase DNA_pol3_delt_C PF14840.1 KUM56811.1 - 0.041 14.0 1.1 0.049 13.7 0.8 1.1 1 0 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term CDRN PF05174.7 KUM56811.1 - 0.1 12.1 1.7 0.19 11.1 1.2 1.5 1 1 0 1 1 1 0 Cysteine-rich D. radiodurans N terminus GFA PF04828.9 KUM56811.1 - 0.12 12.3 0.1 0.17 11.8 0.1 1.2 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme SAM_2 PF07647.12 KUM56814.1 - 2.6e-09 36.7 0.1 5.1e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KUM56814.1 - 4.1e-05 23.6 0.6 8e-05 22.7 0.1 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DHC_N1 PF08385.7 KUM56814.1 - 0.18 10.1 3.5 0.55 8.5 1.5 2.0 1 1 1 2 2 2 0 Dynein heavy chain, N-terminal region 1 Rab5ip PF07019.7 KUM56816.1 - 4.2e-07 30.0 2.4 4.2e-07 30.0 1.7 2.1 2 0 0 2 2 2 1 Rab5-interacting protein (Rab5ip) SecG PF03840.9 KUM56816.1 - 0.035 13.8 0.2 0.035 13.8 0.1 2.1 3 0 0 3 3 3 0 Preprotein translocase SecG subunit TPR_11 PF13414.1 KUM56817.1 - 1.4e-23 82.3 19.3 1.8e-05 24.2 0.1 9.0 6 2 3 10 10 10 5 TPR repeat TPR_19 PF14559.1 KUM56817.1 - 6.4e-21 74.4 11.7 9.7e-07 29.0 0.0 8.2 6 2 2 8 8 8 4 Tetratricopeptide repeat Apc3 PF12895.2 KUM56817.1 - 3.6e-16 59.0 9.9 0.0001 22.3 0.6 6.9 7 1 1 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KUM56817.1 - 4.5e-16 59.0 11.9 2.7e-06 27.9 0.3 6.8 6 1 2 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 KUM56817.1 - 6.9e-14 50.8 5.2 0.023 14.8 0.0 7.5 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 KUM56817.1 - 8.3e-14 50.8 20.0 6.1e-05 23.3 0.3 9.7 6 3 4 10 10 9 3 Tetratricopeptide repeat TPR_7 PF13176.1 KUM56817.1 - 2.3e-12 45.7 8.6 0.2 11.5 0.1 8.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 KUM56817.1 - 1.1e-11 44.4 25.4 0.00016 21.5 0.9 7.0 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 KUM56817.1 - 2.3e-11 42.6 9.5 0.32 10.8 0.0 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 KUM56817.1 - 6.1e-11 41.3 26.5 0.33 10.9 0.0 10.0 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_1 PF00515.23 KUM56817.1 - 2.7e-08 33.0 18.5 0.35 10.5 0.0 9.9 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_15 PF13429.1 KUM56817.1 - 0.00012 21.3 2.8 2.3 7.1 0.0 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 KUM56817.1 - 0.00076 19.2 9.0 0.00079 19.2 0.1 4.6 4 2 1 5 5 5 1 Tetratricopeptide repeat SNAP PF14938.1 KUM56817.1 - 0.0034 16.5 0.6 0.62 9.1 0.0 2.6 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP Alkyl_sulf_dimr PF14863.1 KUM56817.1 - 0.005 17.0 0.5 0.39 10.9 0.0 3.1 3 0 0 3 3 3 1 Alkyl sulfatase dimerisation TPR_20 PF14561.1 KUM56817.1 - 0.0055 16.8 2.0 5.7 7.1 0.0 4.9 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 KUM56817.1 - 0.0056 17.0 13.1 2.2 8.9 0.0 7.2 8 0 0 8 8 7 1 Tetratricopeptide repeat NatB_MDM20 PF09797.4 KUM56817.1 - 0.011 14.4 0.0 2.2 6.9 0.0 2.5 2 0 0 2 2 2 0 N-acetyltransferase B complex (NatB) non catalytic subunit NARP1 PF12569.3 KUM56817.1 - 0.029 13.1 5.3 7.4 5.2 0.0 3.9 3 2 2 5 5 5 0 NMDA receptor-regulated protein 1 ChAPs PF09295.5 KUM56817.1 - 0.12 11.0 0.0 0.5 9.0 0.0 1.9 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) PPR PF01535.15 KUM56817.1 - 1.5 8.9 5.1 3.7 7.7 0.2 3.8 5 0 0 5 5 3 0 PPR repeat TPR_4 PF07721.9 KUM56817.1 - 7.8 7.2 14.7 19 6.0 0.1 6.1 6 0 0 6 6 5 0 Tetratricopeptide repeat MFS_1 PF07690.11 KUM56818.1 - 3.5e-29 101.6 42.2 7.7e-26 90.6 23.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KUM56818.1 - 0.15 12.1 0.1 0.15 12.1 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) PNP_UDP_1 PF01048.15 KUM56819.1 - 1.9e-16 59.7 0.0 2.8e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily Adap_comp_sub PF00928.16 KUM56820.1 - 5e-90 301.1 0.0 6.7e-90 300.7 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KUM56820.1 - 8.3e-09 35.2 0.2 1.3e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 KUM56820.1 - 0.077 12.1 0.0 0.26 10.4 0.0 1.7 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Hydrophobin PF01185.13 KUM56822.1 - 9.4e-15 54.8 7.2 1.3e-14 54.4 5.0 1.2 1 0 0 1 1 1 1 Fungal hydrophobin CFEM PF05730.6 KUM56823.1 - 7.8e-05 22.4 5.6 7.8e-05 22.4 3.9 2.3 2 0 0 2 2 2 1 CFEM domain XRN_N PF03159.13 KUM56823.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus WW PF00397.21 KUM56824.1 - 7.7e-10 38.4 1.6 1.9e-09 37.2 1.1 1.7 1 0 0 1 1 1 1 WW domain Acyl-CoA_dh_M PF02770.14 KUM56825.1 - 0.00029 20.2 0.1 0.00075 18.9 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain NMO PF03060.10 KUM56826.1 - 1.1e-62 212.0 1.0 1.8e-62 211.3 0.7 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KUM56826.1 - 8.6e-11 41.3 0.0 5.2e-08 32.1 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KUM56826.1 - 2.5e-05 23.2 0.2 5e-05 22.3 0.2 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 KUM56826.1 - 0.0091 15.2 0.3 0.059 12.6 0.0 2.0 1 1 0 2 2 2 1 Histidine biosynthesis protein NanE PF04131.9 KUM56826.1 - 0.016 14.2 0.1 0.029 13.3 0.1 1.5 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Glu_synthase PF01645.12 KUM56826.1 - 0.04 12.8 0.4 0.096 11.5 0.2 1.7 1 1 1 2 2 2 0 Conserved region in glutamate synthase DUF1902 PF08972.6 KUM56826.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) Sdh_cyt PF01127.17 KUM56827.1 - 5.9e-24 84.2 5.0 8.1e-24 83.7 3.4 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PepSY_TM_3 PF13706.1 KUM56827.1 - 0.056 12.8 0.1 0.13 11.6 0.1 1.6 1 0 0 1 1 1 0 PepSY-associated TM helix Ribonucleas_3_3 PF14622.1 KUM56828.1 - 3.5e-27 94.9 0.0 6.8e-27 93.9 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KUM56828.1 - 7.8e-05 23.1 0.0 0.00016 22.0 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain Glyco_hydro_72 PF03198.9 KUM56829.1 - 3.3e-133 443.5 4.8 4.2e-133 443.1 3.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 KUM56829.1 - 9.1e-20 70.9 1.4 2.2e-19 69.7 1.0 1.7 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.12 KUM56829.1 - 6.7e-06 25.2 0.1 1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 KUM56829.1 - 0.00045 19.5 0.4 0.0015 17.8 0.3 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CFC PF09443.5 KUM56829.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) Mannitol_dh_C PF08125.8 KUM56831.1 - 2.9e-72 242.7 0.0 4.6e-72 242.1 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 KUM56831.1 - 3.3e-43 147.2 0.0 6.6e-43 146.2 0.0 1.5 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain GMC_oxred_C PF05199.8 KUM56833.1 - 4.7e-34 117.7 0.0 1e-33 116.6 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KUM56833.1 - 4.2e-21 75.3 0.0 3.3e-12 46.1 0.4 2.1 1 1 1 2 2 2 2 GMC oxidoreductase PsiA PF06952.6 KUM56833.1 - 0.044 12.8 0.0 0.07 12.1 0.0 1.2 1 0 0 1 1 1 0 PsiA protein Na_Ca_ex PF01699.19 KUM56835.1 - 4.8e-18 65.1 4.5 4.8e-18 65.1 3.1 2.3 2 1 0 2 2 2 2 Sodium/calcium exchanger protein DUF4282 PF14110.1 KUM56835.1 - 0.0054 16.8 0.3 0.035 14.2 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4282) DUF1385 PF07136.6 KUM56835.1 - 0.22 10.5 2.2 0.23 10.4 0.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1385) Fungal_trans PF04082.13 KUM56836.1 - 1.1e-21 76.8 0.0 1.9e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM56836.1 - 4.5e-05 23.2 7.6 8.2e-05 22.4 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.24 KUM56838.1 - 1.4e-97 322.9 0.0 2.4e-47 160.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 KUM56838.1 - 8.4e-20 70.5 0.8 2.4e-19 69.0 0.4 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 KUM56838.1 - 1.9e-14 53.9 0.0 8.8e-08 32.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KUM56838.1 - 8.6e-14 51.1 0.1 7.4e-06 25.1 0.0 3.1 4 0 0 4 4 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KUM56838.1 - 3.1e-13 49.8 0.0 6.2e-06 26.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KUM56838.1 - 2.1e-12 46.9 0.5 5.4e-06 26.1 0.1 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KUM56838.1 - 9.7e-12 45.1 0.2 0.0018 18.3 0.0 4.3 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KUM56838.1 - 2.2e-11 44.6 0.0 0.0005 20.8 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KUM56838.1 - 6.2e-11 42.6 0.3 0.0019 18.2 0.0 3.9 3 2 1 4 4 3 2 AAA ATPase domain TIP49 PF06068.8 KUM56838.1 - 2.9e-09 36.1 0.1 0.00093 18.0 0.0 2.6 2 0 0 2 2 2 2 TIP49 C-terminus CDC48_2 PF02933.12 KUM56838.1 - 8.3e-09 34.9 0.0 1.9e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_25 PF13481.1 KUM56838.1 - 2.7e-08 33.4 4.5 0.027 13.8 0.0 4.6 3 2 1 5 5 4 2 AAA domain AAA_14 PF13173.1 KUM56838.1 - 3.3e-08 33.4 0.0 0.0035 17.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KUM56838.1 - 5.8e-08 32.3 0.0 0.0053 16.2 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 KUM56838.1 - 1.1e-07 31.2 0.6 0.0085 15.2 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KUM56838.1 - 1.3e-07 30.9 0.0 0.0075 15.3 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.1 KUM56838.1 - 1.5e-07 31.0 1.3 0.0083 15.8 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 KUM56838.1 - 4.8e-07 29.9 0.0 0.024 14.7 0.0 2.9 2 0 0 2 2 2 2 RNA helicase KaiC PF06745.8 KUM56838.1 - 1.7e-06 27.3 1.0 0.45 9.5 0.0 3.5 2 1 1 3 3 3 2 KaiC ResIII PF04851.10 KUM56838.1 - 2.9e-06 27.2 0.0 0.0035 17.1 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_18 PF13238.1 KUM56838.1 - 5.2e-06 26.7 0.0 0.085 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.1 KUM56838.1 - 5.4e-06 26.1 0.0 0.095 12.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 KUM56838.1 - 5.7e-06 26.3 0.0 0.09 12.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.8 KUM56838.1 - 8.2e-06 24.9 0.0 0.011 14.7 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 KUM56838.1 - 1.2e-05 25.1 0.0 4.3 6.9 0.0 4.2 2 2 2 4 4 4 0 Archaeal ATPase Parvo_NS1 PF01057.12 KUM56838.1 - 1.2e-05 24.2 0.1 0.043 12.6 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 KUM56838.1 - 2.6e-05 23.7 0.1 0.3 10.5 0.0 3.4 2 2 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.7 KUM56838.1 - 3.7e-05 23.4 0.1 0.085 12.5 0.0 3.3 3 0 0 3 3 3 1 NACHT domain Vps4_C PF09336.5 KUM56838.1 - 4.8e-05 23.1 0.1 0.00034 20.4 0.0 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Sigma54_activ_2 PF14532.1 KUM56838.1 - 6.1e-05 23.0 0.0 0.33 11.0 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Bac_DnaA PF00308.13 KUM56838.1 - 7e-05 22.5 0.0 0.51 9.9 0.0 3.2 4 0 0 4 4 3 2 Bacterial dnaA protein ABC_tran PF00005.22 KUM56838.1 - 0.00011 22.4 0.0 0.47 10.7 0.0 3.6 3 1 0 3 3 2 1 ABC transporter PhoH PF02562.11 KUM56838.1 - 0.00015 21.0 0.4 0.52 9.5 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_30 PF13604.1 KUM56838.1 - 0.00015 21.3 0.0 0.21 11.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.6 KUM56838.1 - 0.00027 20.5 0.0 0.91 9.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 KUM56838.1 - 0.00072 19.1 0.0 1 8.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.10 KUM56838.1 - 0.0011 18.6 0.5 0.65 9.6 0.0 4.0 4 0 0 4 4 3 1 NTPase DUF2075 PF09848.4 KUM56838.1 - 0.0013 17.8 0.0 1.2 8.0 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 KUM56838.1 - 0.0029 16.4 1.4 0.64 8.8 0.0 2.9 4 0 0 4 4 2 1 NB-ARC domain Viral_helicase1 PF01443.13 KUM56838.1 - 0.0034 16.9 0.0 0.29 10.6 0.0 2.6 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 KUM56838.1 - 0.0061 16.0 0.6 1.6 8.0 0.0 3.7 3 1 0 4 4 4 1 AAA-like domain KAP_NTPase PF07693.9 KUM56838.1 - 0.0077 15.2 0.2 0.92 8.4 0.0 3.2 2 2 1 4 4 4 1 KAP family P-loop domain IPT PF01745.11 KUM56838.1 - 0.014 14.5 0.0 2 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Zot PF05707.7 KUM56838.1 - 0.037 13.5 0.9 12 5.3 0.1 4.2 4 1 0 4 4 4 0 Zonular occludens toxin (Zot) Sec2p PF06428.6 KUM56838.1 - 0.06 13.1 0.7 0.54 10.1 0.6 2.5 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p SKI PF01202.17 KUM56838.1 - 0.069 13.0 0.1 8.1 6.2 0.0 2.9 2 0 0 2 2 2 0 Shikimate kinase AFG1_ATPase PF03969.11 KUM56838.1 - 0.07 11.9 0.0 8.4 5.0 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase UPF0079 PF02367.12 KUM56838.1 - 0.087 12.4 0.1 9.2 5.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 KUM56838.1 - 0.17 11.6 1.5 3.5 7.3 0.0 3.4 4 0 0 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.5 KUM56838.1 - 0.17 11.0 0.5 11 5.1 0.0 2.8 3 0 0 3 3 2 0 Chromatin associated protein KTI12 MFS_1 PF07690.11 KUM56839.1 - 2e-40 138.6 39.6 2e-40 138.6 27.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3464 PF11947.3 KUM56839.1 - 7.6 5.9 7.4 14 5.0 0.0 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3464) HEAT_2 PF13646.1 KUM56840.1 - 4.9e-08 33.1 1.2 2.1e-05 24.7 0.1 5.2 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.17 KUM56840.1 - 0.00018 21.2 12.6 0.042 13.9 0.0 6.2 6 0 0 6 6 6 2 HEAT repeat Adaptin_N PF01602.15 KUM56840.1 - 0.057 11.7 2.0 0.91 7.7 0.0 3.4 4 1 0 4 4 4 0 Adaptin N terminal region HEAT_EZ PF13513.1 KUM56840.1 - 0.1 13.1 7.3 2 8.9 0.0 4.9 5 0 0 5 5 5 0 HEAT-like repeat SNF5 PF04855.7 KUM56841.1 - 2e-76 256.6 0.7 3.2e-76 256.0 0.5 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Exo_endo_phos PF03372.18 KUM56842.1 - 7.5e-11 42.4 0.2 1.2e-10 41.7 0.1 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M24 PF00557.19 KUM56844.1 - 8.9e-12 45.0 0.1 1.2e-11 44.5 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DAO PF01266.19 KUM56845.1 - 1.7e-26 93.0 0.1 1.3e-25 90.0 0.1 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KUM56845.1 - 0.00039 20.4 0.0 0.00099 19.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KUM56845.1 - 0.00044 19.4 0.8 0.00063 18.8 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 KUM56845.1 - 0.00056 19.6 0.8 0.0013 18.4 0.2 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KUM56845.1 - 0.0016 17.3 0.0 0.0025 16.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KUM56845.1 - 0.0043 17.1 0.0 0.0065 16.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KUM56845.1 - 0.014 15.8 1.5 0.029 14.7 1.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 KUM56845.1 - 0.014 14.5 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KUM56845.1 - 0.019 15.1 0.0 0.032 14.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.9 KUM56845.1 - 0.02 14.7 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 KUM56845.1 - 0.022 15.2 0.0 0.042 14.2 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 KUM56845.1 - 0.023 14.1 0.5 0.023 14.1 0.3 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 KUM56845.1 - 0.023 14.0 1.2 0.049 13.0 0.8 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 KUM56845.1 - 0.041 13.7 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 KUM56845.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain LRR_4 PF12799.2 KUM56846.1 - 3.5e-05 23.3 8.6 0.038 13.6 0.9 4.5 2 2 4 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KUM56846.1 - 0.016 15.1 4.7 24 5.4 0.0 5.9 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.1 KUM56846.1 - 0.016 14.9 7.2 0.28 10.9 0.6 4.3 4 1 0 4 4 4 0 Leucine rich repeat LRR_7 PF13504.1 KUM56846.1 - 0.016 15.2 1.3 40 5.0 0.0 5.4 5 0 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 KUM56846.1 - 0.17 12.0 8.0 4.9 7.5 0.0 5.1 5 1 1 6 6 6 0 Leucine Rich repeat DUF4293 PF14126.1 KUM56847.1 - 0.93 9.4 4.7 1.6 8.6 3.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) Herpes_UL14 PF03580.9 KUM56848.1 - 0.019 14.7 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL14-like protein JmjN PF02375.12 KUM56848.1 - 0.1 12.1 0.7 0.2 11.2 0.1 1.8 2 0 0 2 2 2 0 jmjN domain SET PF00856.23 KUM56849.1 - 9.5e-10 39.0 0.2 4.3e-09 36.8 0.1 2.0 1 1 0 1 1 1 1 SET domain Hydrolase_6 PF13344.1 KUM56850.1 - 1.6e-21 76.0 0.0 2.8e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KUM56850.1 - 1.5e-18 66.2 0.0 5.1e-18 64.5 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 KUM56850.1 - 0.0024 18.1 0.0 0.13 12.4 0.0 2.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KUM56850.1 - 0.013 15.8 0.0 0.25 11.7 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 KUM56850.1 - 0.033 13.5 0.0 0.063 12.6 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Apt1 PF10351.4 KUM56850.1 - 0.069 11.9 0.0 0.15 10.8 0.0 1.5 2 0 0 2 2 2 0 Golgi-body localisation protein domain Glyco_hydro_12 PF01670.11 KUM56851.1 - 2.3e-51 173.6 1.4 2.3e-51 173.6 0.9 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 Fungal_trans PF04082.13 KUM56852.1 - 3.8e-25 88.2 0.0 7.5e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Josephin PF02099.12 KUM56852.1 - 0.056 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Josephin DUF1275 PF06912.6 KUM56852.1 - 0.098 11.8 1.2 3.7 6.6 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1275) Aminotran_3 PF00202.16 KUM56853.1 - 3.3e-82 276.0 0.0 4.1e-82 275.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 KUM56853.1 - 0.16 11.0 0.0 1.8 7.6 0.0 2.1 1 1 0 1 1 1 0 Beta-eliminating lyase HAD_2 PF13419.1 KUM56855.1 - 5e-33 114.7 0.0 6.3e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase AraC_N PF06719.8 KUM56855.1 - 0.011 15.0 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 AraC-type transcriptional regulator N-terminus SAP30_Sin3_bdg PF13867.1 KUM56855.1 - 0.043 13.7 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Aldedh PF00171.17 KUM56856.1 - 1.3e-165 551.2 0.1 1.5e-165 551.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1726 PF08351.6 KUM56856.1 - 0.025 14.2 0.0 0.067 12.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) DUF1487 PF07368.6 KUM56856.1 - 0.088 12.0 0.0 0.43 9.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) F-box-like PF12937.2 KUM56858.1 - 0.084 12.6 0.8 0.19 11.5 0.5 1.6 1 0 0 1 1 1 0 F-box-like Glyco_hydro_16 PF00722.16 KUM56860.1 - 1.9e-43 147.9 4.0 2.4e-43 147.5 2.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MSC PF09402.5 KUM56861.1 - 4.3e-96 321.5 0.0 5.7e-96 321.1 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 KUM56861.1 - 1.8e-16 59.3 0.0 3.5e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 HeH/LEM domain DUF3350 PF11830.3 KUM56861.1 - 0.14 12.1 7.3 1.5 8.9 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3350) PP2C PF00481.16 KUM56863.1 - 1.4e-51 175.3 0.0 2.4e-51 174.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 KUM56863.1 - 7.6e-51 169.0 54.6 2e-07 30.4 0.6 12.3 8 3 4 12 12 12 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KUM56863.1 - 1.3e-38 130.5 59.7 9e-08 31.7 0.5 10.7 6 4 6 12 12 12 10 Leucine rich repeat Guanylate_cyc PF00211.15 KUM56863.1 - 2.5e-26 92.1 0.0 4.5e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 KUM56863.1 - 5.4e-19 65.3 59.5 0.73 10.0 0.1 18.4 17 1 1 18 18 18 8 Leucine Rich Repeat LRR_7 PF13504.1 KUM56863.1 - 8.1e-09 34.2 44.7 3.2 8.3 0.2 15.4 16 1 0 16 16 15 2 Leucine rich repeat RA PF00788.18 KUM56863.1 - 4.1e-07 30.4 0.0 1e-06 29.0 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_5 PF13306.1 KUM56863.1 - 2e-05 24.3 10.5 0.56 9.9 1.5 4.7 3 2 1 4 4 4 3 Leucine rich repeats (6 copies) Ad_cyc_g-alpha PF08509.6 KUM56863.1 - 0.001 18.3 0.2 0.0047 16.2 0.1 2.1 2 0 0 2 2 2 1 Adenylate cyclase G-alpha binding domain LRR_6 PF13516.1 KUM56863.1 - 0.0019 18.0 48.3 5.2 7.4 0.1 14.7 15 1 1 16 16 16 1 Leucine Rich repeat LRR_9 PF14580.1 KUM56863.1 - 0.4 10.2 6.5 35 3.8 0.2 4.2 3 1 3 6 6 6 0 Leucine-rich repeat ABC_tran PF00005.22 KUM56865.1 - 4.1e-45 153.4 0.0 3.8e-24 85.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KUM56865.1 - 2.3e-36 125.6 29.4 9.3e-25 87.5 9.5 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KUM56865.1 - 4.1e-17 62.1 0.3 0.0015 17.7 0.0 4.2 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KUM56865.1 - 5.4e-12 46.2 1.1 0.017 15.1 0.0 4.3 2 2 1 4 4 4 3 AAA domain AAA_29 PF13555.1 KUM56865.1 - 1.5e-08 34.0 0.3 0.0027 17.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KUM56865.1 - 2.5e-07 30.0 0.2 0.015 14.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KUM56865.1 - 4.3e-07 30.4 0.1 0.021 15.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 KUM56865.1 - 6.4e-07 28.5 0.2 0.027 13.3 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 KUM56865.1 - 3.9e-06 26.9 0.7 0.055 13.4 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_10 PF12846.2 KUM56865.1 - 6.9e-06 25.7 0.0 0.02 14.3 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain Arch_ATPase PF01637.13 KUM56865.1 - 1.1e-05 25.2 0.0 0.021 14.5 0.0 2.7 2 0 0 2 2 2 2 Archaeal ATPase AAA_22 PF13401.1 KUM56865.1 - 1.9e-05 24.8 0.2 0.18 11.9 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KUM56865.1 - 1.9e-05 24.1 0.0 0.2 11.0 0.0 2.8 3 0 0 3 3 3 2 AAA domain FtsK_SpoIIIE PF01580.13 KUM56865.1 - 5.4e-05 22.7 0.5 0.098 12.1 0.0 2.6 3 0 0 3 3 2 2 FtsK/SpoIIIE family DUF815 PF05673.8 KUM56865.1 - 0.00016 20.6 0.2 0.071 12.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) SbcCD_C PF13558.1 KUM56865.1 - 0.00017 21.4 0.1 0.072 13.0 0.0 2.7 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 KUM56865.1 - 0.00018 21.4 0.4 1 9.3 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase Zeta_toxin PF06414.7 KUM56865.1 - 0.00028 20.0 0.1 0.39 9.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Adeno_IVa2 PF02456.10 KUM56865.1 - 0.00036 19.3 0.1 0.2 10.2 0.0 2.2 2 0 0 2 2 2 2 Adenovirus IVa2 protein cobW PF02492.14 KUM56865.1 - 0.00084 18.8 1.5 0.19 11.1 0.1 2.8 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 KUM56865.1 - 0.00099 18.8 0.0 0.55 10.0 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain Miro PF08477.8 KUM56865.1 - 0.0015 19.0 0.1 2.2 8.7 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_17 PF13207.1 KUM56865.1 - 0.0022 18.8 0.1 3 8.6 0.0 3.0 3 0 0 3 3 2 1 AAA domain Sigma54_activat PF00158.21 KUM56865.1 - 0.0023 17.4 0.0 2.1 7.7 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain MobB PF03205.9 KUM56865.1 - 0.0031 17.2 0.1 2.7 7.6 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 KUM56865.1 - 0.0049 16.7 1.2 0.23 11.2 0.1 2.4 2 0 0 2 2 2 1 Dynamin family TrwB_AAD_bind PF10412.4 KUM56865.1 - 0.0087 14.7 0.1 2.5 6.6 0.0 2.2 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.10 KUM56865.1 - 0.015 14.9 0.1 0.39 10.4 0.0 2.4 2 0 0 2 2 2 0 NTPase NACHT PF05729.7 KUM56865.1 - 0.017 14.7 1.1 2.7 7.6 0.1 2.6 2 0 0 2 2 2 0 NACHT domain RNA12 PF10443.4 KUM56865.1 - 0.025 13.0 0.1 1 7.7 0.0 2.2 2 0 0 2 2 2 0 RNA12 protein AAA_5 PF07728.9 KUM56865.1 - 0.031 14.0 0.6 3 7.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zot PF05707.7 KUM56865.1 - 0.041 13.3 0.0 0.3 10.5 0.0 2.2 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_33 PF13671.1 KUM56865.1 - 0.042 13.7 0.0 1.4 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KUM56865.1 - 0.043 14.1 0.1 8.7 6.6 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KUM56865.1 - 0.062 13.5 0.0 1.5 9.0 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 KUM56865.1 - 0.081 12.7 0.4 0.92 9.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_15 PF13175.1 KUM56865.1 - 0.14 11.1 0.2 2.4 7.0 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 KUM56865.1 - 0.19 11.6 0.1 33 4.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KUM56865.1 - 0.19 11.3 1.1 26 4.4 0.0 3.1 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 KUM56865.1 - 0.23 10.9 0.1 3 7.2 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 KUM56865.1 - 0.23 10.9 0.1 3.5 7.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Herpes_Helicase PF02689.9 KUM56865.1 - 0.24 9.1 0.0 0.36 8.5 0.0 1.1 1 0 0 1 1 1 0 Helicase AAA_11 PF13086.1 KUM56865.1 - 0.25 10.8 0.0 1.8 8.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Tannase PF07519.6 KUM56866.1 - 9.6e-84 281.7 0.3 7.3e-43 146.9 0.1 2.0 1 1 1 2 2 2 2 Tannase and feruloyl esterase Peptidase_S9 PF00326.16 KUM56866.1 - 6.5e-06 25.5 0.1 0.1 11.8 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KUM56866.1 - 0.00024 21.0 0.0 0.00058 19.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM56866.1 - 0.0027 17.4 0.3 0.2 11.3 0.2 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family CAT PF00302.13 KUM56866.1 - 0.0072 15.9 0.3 0.011 15.3 0.2 1.3 1 0 0 1 1 1 1 Chloramphenicol acetyltransferase Abhydrolase_1 PF00561.15 KUM56866.1 - 0.03 13.8 0.1 0.063 12.8 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3176 PF11374.3 KUM56867.1 - 2.1e-27 95.1 0.7 4.2e-27 94.2 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) NAD_binding_10 PF13460.1 KUM56868.1 - 4.8e-28 98.3 0.0 5.6e-28 98.1 0.0 1.0 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KUM56868.1 - 4e-09 36.0 0.0 8.8e-09 34.9 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KUM56868.1 - 5.3e-06 26.0 0.0 8.3e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 KUM56868.1 - 0.0073 16.2 0.0 0.017 15.1 0.0 1.7 1 1 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 KUM56868.1 - 0.038 12.6 0.0 0.059 12.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 KUM56868.1 - 0.082 12.8 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NIF PF03031.13 KUM56869.1 - 1.7e-23 83.0 0.0 9.9e-23 80.5 0.0 2.0 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase DUF947 PF06102.7 KUM56870.1 - 3.6e-45 153.8 23.4 3.6e-45 153.8 16.2 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF947) EF1G PF00647.14 KUM56872.1 - 1.6e-41 140.3 0.2 3e-41 139.4 0.1 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 KUM56872.1 - 4.6e-13 48.9 0.0 9.6e-13 47.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KUM56872.1 - 2.6e-11 43.2 0.1 2e-10 40.4 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KUM56872.1 - 2.9e-09 36.9 0.0 7.8e-09 35.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KUM56872.1 - 1.2e-05 25.7 0.1 0.00013 22.3 0.1 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KUM56872.1 - 2.3e-05 24.5 0.0 5.1e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KUM56872.1 - 0.0057 16.6 0.0 0.022 14.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Ribosomal_S9 PF00380.14 KUM56874.1 - 3.1e-35 121.0 0.4 5.3e-35 120.2 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Aminotran_5 PF00266.14 KUM56876.1 - 1.1e-49 169.1 0.0 1.3e-48 165.5 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KUM56876.1 - 3.5e-05 22.9 0.0 5.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KUM56876.1 - 0.00068 18.0 0.0 0.0012 17.2 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KUM56876.1 - 0.049 12.6 0.0 0.069 12.1 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Robl_LC7 PF03259.12 KUM56877.1 - 4.6e-07 29.3 0.1 0.003 17.0 0.0 3.1 3 0 0 3 3 3 2 Roadblock/LC7 domain Peptidase_S30 PF01577.11 KUM56878.1 - 1 8.7 4.2 2.6 7.3 0.3 2.2 2 0 0 2 2 2 0 Potyvirus P1 protease Ipi1_N PF12333.3 KUM56881.1 - 7.7e-31 106.1 0.1 7.3e-30 102.9 0.0 2.3 2 1 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.17 KUM56881.1 - 0.13 12.3 0.9 6.6 7.0 0.1 2.9 3 0 0 3 3 3 0 HEAT repeat AreA_N PF07573.6 KUM56883.1 - 3.2e-17 62.8 4.9 3.2e-17 62.8 3.4 3.7 4 0 0 4 4 4 1 Nitrogen regulatory protein AreA N terminus GATA PF00320.22 KUM56883.1 - 1.5e-16 59.4 1.9 2.8e-16 58.5 1.3 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 KUM56883.1 - 1.3e-13 50.2 5.4 1.3e-13 50.2 3.7 1.9 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) DUF3480 PF11979.3 KUM56883.1 - 0.27 9.8 0.0 0.4 9.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3480) FAD_binding_3 PF01494.14 KUM56884.1 - 1.4e-09 37.4 2.0 1.4e-08 34.2 1.4 2.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KUM56884.1 - 5e-05 22.3 0.6 0.0044 15.9 0.1 2.9 2 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KUM56884.1 - 0.00079 19.2 0.1 0.0023 17.7 0.0 1.7 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KUM56884.1 - 0.0012 18.8 0.0 0.003 17.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KUM56884.1 - 0.0017 17.3 0.2 0.016 14.1 0.1 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein Amino_oxidase PF01593.19 KUM56884.1 - 0.02 13.9 0.0 0.034 13.2 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 KUM56884.1 - 0.089 11.4 0.1 0.23 10.0 0.0 1.7 1 1 1 2 2 2 0 Tryptophan halogenase Calcipressin PF04847.7 KUM56885.1 - 3.7e-31 108.1 0.7 5.3e-31 107.6 0.5 1.2 1 0 0 1 1 1 1 Calcipressin Cellulase-like PF12876.2 KUM56885.1 - 0.068 13.6 0.1 0.21 12.0 0.1 1.8 1 0 0 1 1 1 0 Sugar-binding cellulase-like BLVR PF06375.6 KUM56886.1 - 0.086 12.6 4.3 0.1 12.3 3.0 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) ATE_C PF04377.10 KUM56887.1 - 1.3e-45 154.5 0.9 2e-45 153.9 0.6 1.2 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus Acetyltransf_6 PF13480.1 KUM56887.1 - 0.0004 20.3 0.2 0.00067 19.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Neil1-DNA_bind PF09292.5 KUM56887.1 - 0.48 10.2 2.2 9 6.1 0.3 2.5 2 0 0 2 2 2 0 Endonuclease VIII-like 1, DNA bind RNA_pol_A_bac PF01000.21 KUM56888.1 - 1e-30 106.1 0.0 1.6e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KUM56888.1 - 1.1e-11 43.7 0.0 1.7e-11 43.0 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain NUDIX PF00293.23 KUM56889.1 - 9.9e-18 64.0 0.3 1.2e-17 63.8 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain GrpE PF01025.14 KUM56891.1 - 6e-41 139.7 6.8 9.5e-41 139.1 4.7 1.3 1 0 0 1 1 1 1 GrpE Phage_Gp23 PF10669.4 KUM56891.1 - 0.0099 15.9 2.2 0.023 14.7 1.5 1.6 1 0 0 1 1 1 1 Protein gp23 (Bacteriophage A118) Focal_AT PF03623.8 KUM56891.1 - 0.034 13.6 0.9 0.072 12.5 0.6 1.6 1 1 0 1 1 1 0 Focal adhesion targeting region Herpes_glycop_H PF02489.11 KUM56891.1 - 0.04 11.9 0.3 0.049 11.6 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein H MFS_1 PF07690.11 KUM56892.1 - 1.9e-22 79.4 32.3 1.9e-22 79.4 22.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily AA_permease_2 PF13520.1 KUM56893.1 - 5.2e-74 249.2 36.4 6.9e-74 248.8 25.2 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM56893.1 - 1.3e-12 46.8 31.7 2e-12 46.2 21.9 1.2 1 0 0 1 1 1 1 Amino acid permease tRNA-synt_2d PF01409.15 KUM56894.1 - 7.6e-47 159.5 0.4 1.4e-22 80.1 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 KUM56894.1 - 1.6e-25 89.0 0.0 5.5e-25 87.3 0.0 1.9 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain Herpes_U30 PF04523.8 KUM56894.1 - 0.067 10.6 0.0 0.097 10.1 0.0 1.1 1 0 0 1 1 1 0 Herpes virus tegument protein U30 Mito_carr PF00153.22 KUM56895.1 - 1.2e-16 60.1 5.4 5.3e-15 54.9 0.3 3.1 2 1 0 2 2 2 1 Mitochondrial carrier protein Macro PF01661.16 KUM56896.1 - 3e-40 136.8 0.0 3.9e-40 136.4 0.0 1.2 1 0 0 1 1 1 1 Macro domain DUF3929 PF13066.1 KUM56896.1 - 0.15 11.8 1.3 6.1 6.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3929) Peptidase_S24 PF00717.18 KUM56897.1 - 4.9e-08 32.4 0.1 4.1e-07 29.5 0.1 2.1 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 KUM56897.1 - 0.0083 15.6 0.0 1.4 8.3 0.0 2.5 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 VSP PF03302.8 KUM56900.1 - 8e-05 21.4 2.9 8e-05 21.4 2.0 1.6 1 1 0 1 1 1 1 Giardia variant-specific surface protein Podoplanin PF05808.6 KUM56900.1 - 0.012 15.1 0.1 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Podoplanin GRA6 PF05084.8 KUM56900.1 - 0.02 14.4 0.3 0.031 13.7 0.2 1.2 1 0 0 1 1 1 0 Granule antigen protein (GRA6) YebO PF13974.1 KUM56900.1 - 0.15 11.8 0.6 0.23 11.2 0.4 1.2 1 0 0 1 1 1 0 YebO-like protein PH_4 PF15404.1 KUM56901.1 - 5.4e-60 202.1 0.0 2.3e-59 200.0 0.0 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain Spo7_2_N PF15407.1 KUM56901.1 - 8.2e-20 70.0 0.2 1.7e-19 69.0 0.1 1.6 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.24 KUM56901.1 - 3.7e-11 43.1 0.0 4.1e-06 26.9 0.0 3.9 3 1 0 3 3 3 2 PH domain PH_6 PF15406.1 KUM56901.1 - 0.0096 15.9 0.1 2.9 7.9 0.0 2.8 2 0 0 2 2 2 2 Pleckstrin homology domain GLTP PF08718.6 KUM56902.1 - 3e-46 157.1 0.0 4.1e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Cir_N PF10197.4 KUM56902.1 - 0.038 14.0 0.4 0.095 12.7 0.1 1.7 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR DUF1479 PF07350.7 KUM56904.1 - 1.9e-164 547.1 0.0 2.2e-164 546.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) DUF3759 PF12585.3 KUM56905.1 - 7.3e-40 134.7 11.3 8.4e-40 134.5 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) EXS PF03124.9 KUM56906.1 - 3.8e-93 312.2 35.3 4.8e-93 311.9 24.4 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 KUM56906.1 - 1.8e-65 221.4 0.7 3e-65 220.7 0.5 1.3 1 0 0 1 1 1 1 SPX domain Selenoprotein_S PF06936.6 KUM56906.1 - 0.5 9.8 4.0 0.3 10.6 0.2 2.3 2 0 0 2 2 2 0 Selenoprotein S (SelS) Aa_trans PF01490.13 KUM56907.1 - 8.2e-40 136.5 35.9 9.6e-40 136.3 24.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Bax1-I PF01027.15 KUM56908.1 - 7.2e-48 162.9 30.1 8.4e-48 162.7 20.9 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Spore_YhaL PF14147.1 KUM56908.1 - 0.075 12.4 0.2 0.24 10.8 0.1 1.9 1 0 0 1 1 1 0 Sporulation protein YhaL Aa_trans PF01490.13 KUM56909.1 - 3.2e-93 312.4 13.1 4.5e-93 311.9 9.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KUM56909.1 - 2.4e-06 26.6 15.5 2.4e-06 26.6 10.8 1.7 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family adh_short PF00106.20 KUM56910.1 - 6.7e-16 58.6 0.1 4.9e-15 55.8 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM56910.1 - 6.3e-09 35.9 0.0 2.2e-08 34.1 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM56910.1 - 2.7e-06 27.1 0.0 0.00084 19.0 0.0 2.1 2 0 0 2 2 2 2 KR domain DNA_ligase_A_C PF04679.10 KUM56910.1 - 0.14 12.5 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region RasGAP PF00616.14 KUM56912.1 - 2.4e-43 148.0 0.0 5.4e-43 146.9 0.0 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 KUM56912.1 - 1.4e-06 28.0 0.0 4.1e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 C2 domain Aminotran_1_2 PF00155.16 KUM56914.1 - 1.6e-40 139.1 0.0 1.9e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KUM56914.1 - 0.022 13.0 0.0 0.05 11.8 0.0 1.5 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme HpaP PF09483.5 KUM56915.1 - 0.57 10.1 6.5 0.21 11.5 1.9 1.9 2 0 0 2 2 2 0 Type III secretion protein (HpaP) WD40 PF00400.27 KUM56917.1 - 6.4e-16 57.5 1.7 0.00046 19.9 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat Glyco_hydro_17 PF00332.13 KUM56918.1 - 4.2e-07 29.3 0.0 1.9e-05 23.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 Glucan_synthase PF02364.10 KUM56919.1 - 0 1479.3 0.0 0 1478.8 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 KUM56919.1 - 1.6e-39 134.4 0.4 3.6e-39 133.3 0.3 1.6 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 AMP-binding PF00501.23 KUM56920.1 - 7e-92 307.9 0.0 9.8e-92 307.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KUM56920.1 - 2.9e-13 50.5 0.8 7.8e-13 49.1 0.5 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acetyltransf_1 PF00583.19 KUM56921.1 - 8.4e-05 22.5 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KUM56921.1 - 0.00093 19.3 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_hydro_72 PF03198.9 KUM56922.1 - 1.5e-124 415.1 1.4 1.9e-124 414.7 1.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 KUM56922.1 - 3e-05 23.3 0.0 0.0033 16.6 0.0 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RAP1 PF07218.6 KUM56922.1 - 2 6.3 18.3 2.8 5.9 12.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) F-box-like PF12937.2 KUM56923.1 - 9.3e-10 38.0 0.2 2.1e-09 36.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KUM56923.1 - 3.1e-08 33.0 0.5 7.3e-08 31.8 0.0 1.8 2 0 0 2 2 2 1 F-box domain DUF1446 PF07287.6 KUM56924.1 - 9.3e-127 422.4 0.1 1.1e-126 422.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Mre11_DNA_bind PF04152.9 KUM56925.1 - 1.2e-59 201.0 0.6 1.2e-59 201.0 0.4 2.3 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 KUM56925.1 - 6.4e-25 87.7 1.7 9.2e-25 87.2 1.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KUM56925.1 - 3.5e-05 23.6 0.0 8.5e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 KUM56925.1 - 0.069 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Ldh_1_N PF00056.18 KUM56926.1 - 7.5e-42 142.4 0.0 1.1e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KUM56926.1 - 1.2e-38 132.6 0.0 1.6e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 KUM56926.1 - 0.00015 20.5 0.0 0.00025 19.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 KUM56926.1 - 0.00046 19.5 0.5 0.4 9.9 0.0 2.4 1 1 1 2 2 2 2 Family 4 glycosyl hydrolase Methyltransf_23 PF13489.1 KUM56927.1 - 2.5e-10 40.3 0.0 3.5e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM56927.1 - 2.6e-10 40.8 0.0 6.2e-10 39.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM56927.1 - 1.3e-08 34.5 0.1 8.6e-06 25.4 0.1 2.4 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 KUM56927.1 - 4.1e-05 23.5 0.0 6.6e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KUM56927.1 - 4.4e-05 23.1 0.0 7.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.1 KUM56927.1 - 0.0027 18.5 0.0 0.0056 17.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM56927.1 - 0.0038 17.6 0.0 0.018 15.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KUM56927.1 - 0.0042 17.1 0.0 0.0056 16.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.7 KUM56927.1 - 0.0069 16.8 0.0 0.021 15.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM56927.1 - 0.015 15.6 0.0 0.035 14.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 KUM56927.1 - 0.033 13.2 0.1 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 KUM56927.1 - 0.05 12.7 0.0 0.16 11.0 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.6 KUM56927.1 - 0.065 11.9 0.0 0.47 9.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) IGPD PF00475.13 KUM56929.1 - 9.3e-57 190.9 0.4 1.3e-56 190.5 0.3 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase DUF2917 PF11142.3 KUM56929.1 - 0.033 13.3 0.0 0.074 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2917) Abhydrolase_6 PF12697.2 KUM56930.1 - 2.3e-10 40.7 0.0 4.3e-10 39.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM56930.1 - 5.8e-09 35.8 0.0 1.1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KUM56930.1 - 7.2e-05 22.5 0.0 0.00022 20.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 KUM56930.1 - 0.094 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Cutinase Muted PF14942.1 KUM56933.1 - 7.3 6.4 9.6 1.3 8.8 3.4 1.8 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein DER1 PF04511.10 KUM56934.1 - 4.1e-49 166.7 4.4 4.7e-49 166.5 3.1 1.0 1 0 0 1 1 1 1 Der1-like family DUF4395 PF14340.1 KUM56934.1 - 6.7 6.7 7.7 2.9 7.9 2.9 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4395) Gly_transf_sug PF04488.10 KUM56935.1 - 2.5e-18 66.3 0.0 4.1e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Cohesin_load PF10345.4 KUM56936.1 - 2.5e-171 570.9 5.3 3.2e-171 570.6 3.7 1.0 1 0 0 1 1 1 1 Cohesin loading factor DUF3323 PF11796.3 KUM56936.1 - 0.0019 17.5 1.5 0.0019 17.5 1.0 1.9 2 0 0 2 2 2 1 Protein of unknown function N-terminus (DUF3323) TPR_12 PF13424.1 KUM56936.1 - 0.2 11.6 0.1 0.2 11.6 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat Histone PF00125.19 KUM56937.1 - 1.2e-27 95.8 0.2 1.8e-27 95.2 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KUM56937.1 - 0.00053 20.1 0.1 0.00093 19.3 0.1 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 KUM56937.1 - 0.0085 15.3 0.4 0.01 15.1 0.2 1.2 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 KUM56937.1 - 0.0095 15.9 0.4 0.022 14.8 0.3 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Complex1_LYR_2 PF13233.1 KUM56939.1 - 5.8e-06 26.7 0.1 7.4e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KUM56939.1 - 4.9e-05 23.0 0.0 9.9e-05 22.0 0.0 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KUM56939.1 - 0.00029 20.9 0.0 0.00046 20.3 0.0 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Aldo_ket_red PF00248.16 KUM56941.1 - 5.2e-49 166.5 0.0 6.2e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Nefa_Nip30_N PF10187.4 KUM56942.1 - 1.3e-29 102.3 13.6 1.3e-29 102.3 9.5 2.0 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.8 KUM56942.1 - 0.024 13.8 19.0 0.028 13.6 13.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF932 PF06067.6 KUM56942.1 - 0.028 13.7 4.3 0.039 13.2 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF932) DUF2075 PF09848.4 KUM56942.1 - 0.067 12.1 3.0 0.083 11.8 2.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sugar_tr PF00083.19 KUM56943.1 - 3.5e-102 342.3 19.7 4e-102 342.1 13.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM56943.1 - 3.6e-33 114.7 26.0 1.3e-24 86.6 3.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Bac_luciferase PF00296.15 KUM56945.1 - 2.6e-63 213.9 0.1 3.2e-63 213.6 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Alpha-L-AF_C PF06964.7 KUM56946.1 - 1.2e-36 126.1 0.7 1.7e-36 125.6 0.5 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus p450 PF00067.17 KUM56947.1 - 8.7e-54 182.7 0.0 9.6e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3716 PF12511.3 KUM56950.1 - 6.1e-11 41.7 4.9 6.1e-11 41.7 3.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3716) E1-E2_ATPase PF00122.15 KUM56951.1 - 2e-64 216.7 0.8 2e-64 216.7 0.5 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KUM56951.1 - 5.3e-46 156.4 8.2 5.3e-46 156.4 5.7 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KUM56951.1 - 2.5e-27 96.6 1.0 3.6e-26 92.9 0.7 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KUM56951.1 - 2.3e-17 62.7 0.0 4.5e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KUM56951.1 - 1.1e-13 51.7 0.0 2.5e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KUM56951.1 - 1.8e-08 33.6 0.2 6.2e-08 31.9 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KUM56951.1 - 4.2e-06 26.5 2.2 0.00013 21.6 0.9 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Tannase PF07519.6 KUM56952.1 - 2.8e-99 333.0 1.8 4e-99 332.4 1.2 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 KUM56952.1 - 0.0068 16.1 0.0 0.12 12.1 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KUM56952.1 - 0.091 12.6 0.0 0.23 11.3 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family D-ser_dehydrat PF14031.1 KUM56953.1 - 4.2e-23 81.3 0.1 9.3e-23 80.2 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 KUM56953.1 - 4.6e-12 45.9 0.0 7e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Rad60-SLD PF11976.3 KUM56954.1 - 3e-21 74.8 0.2 3.5e-21 74.6 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KUM56954.1 - 8.5e-09 34.6 0.1 1.1e-08 34.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family SRP9-21 PF05486.7 KUM56954.1 - 0.031 14.0 0.1 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) Nup84_Nup100 PF04121.8 KUM56955.1 - 8.2e-61 205.5 0.0 1e-59 201.9 0.0 2.5 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 AAA_18 PF13238.1 KUM56956.1 - 1.4e-06 28.6 0.0 2.5e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KUM56956.1 - 0.011 15.6 0.0 0.015 15.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KUM56956.1 - 0.017 15.9 0.0 0.023 15.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain CPT PF07931.7 KUM56956.1 - 0.023 14.3 0.0 2.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.1 KUM56956.1 - 0.023 14.6 0.1 0.041 13.8 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KUM56956.1 - 0.028 14.5 0.0 0.076 13.1 0.0 1.6 1 1 1 2 2 2 0 AAA domain KTI12 PF08433.5 KUM56956.1 - 0.069 12.3 0.0 0.095 11.8 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF1903 PF08991.5 KUM56959.1 - 1e-15 57.6 5.3 1e-15 57.6 3.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1903) CHCH PF06747.8 KUM56959.1 - 0.046 13.6 6.2 0.046 13.6 4.3 1.8 2 0 0 2 2 2 0 CHCH domain Fz PF01392.17 KUM56959.1 - 0.1 12.9 3.8 0.14 12.4 2.7 1.2 1 0 0 1 1 1 0 Fz domain Cmc1 PF08583.5 KUM56959.1 - 3.1 7.6 8.0 0.19 11.5 1.6 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Nipped-B_C PF12830.2 KUM56960.1 - 1.5e-50 171.4 1.4 1.5e-50 171.4 1.0 3.0 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 KUM56960.1 - 5.4e-13 48.5 0.9 2.8e-12 46.2 0.2 2.7 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 KUM56960.1 - 0.00058 19.7 3.5 0.02 14.7 0.0 3.8 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 MA3 PF02847.12 KUM56960.1 - 0.0037 16.9 1.2 2.4 7.9 0.0 4.0 4 0 0 4 4 4 2 MA3 domain HEAT PF02985.17 KUM56960.1 - 0.34 11.1 5.8 3.4 7.9 0.0 4.9 6 0 0 6 6 6 0 HEAT repeat CLTH PF10607.4 KUM56961.1 - 4.2e-33 114.0 0.0 5.5e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KUM56961.1 - 1.2e-09 37.5 0.0 2.4e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 LisH Pyr_redox_2 PF07992.9 KUM56962.1 - 2.3e-19 70.0 0.0 4.3e-19 69.1 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KUM56962.1 - 1.6e-13 50.8 0.0 1.9e-11 44.2 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.1 KUM56962.1 - 2.6e-05 24.2 0.0 7.4e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KUM56962.1 - 5.8e-05 22.1 0.0 0.00016 20.7 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KUM56962.1 - 0.00081 19.0 0.1 0.0024 17.6 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 KUM56962.1 - 0.0023 17.1 0.0 0.0061 15.8 0.0 1.6 1 0 0 1 1 1 1 EF hand Methyltrn_RNA_4 PF09936.4 KUM56962.1 - 0.12 11.8 0.0 0.51 9.8 0.0 2.0 2 0 0 2 2 2 0 SAM-dependent RNA methyltransferase Myc_N PF01056.13 KUM56962.1 - 0.27 10.3 0.0 0.4 9.7 0.0 1.1 1 0 0 1 1 1 0 Myc amino-terminal region TFIIS_C PF01096.13 KUM56963.1 - 3.3e-13 49.0 3.1 3.3e-13 49.0 2.1 3.2 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KUM56963.1 - 5.1e-05 22.8 0.6 5.1e-05 22.8 0.4 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit zinc_ribbon_2 PF13240.1 KUM56963.1 - 0.0014 18.0 1.8 0.079 12.4 0.1 2.9 2 1 0 2 2 2 1 zinc-ribbon domain DZR PF12773.2 KUM56963.1 - 0.003 17.3 3.1 0.061 13.1 0.2 2.6 2 0 0 2 2 2 1 Double zinc ribbon Nudix_N_2 PF14803.1 KUM56963.1 - 0.029 14.0 2.3 14 5.4 0.0 3.4 3 0 0 3 3 3 0 Nudix N-terminal DUF2072 PF09845.4 KUM56963.1 - 0.1 12.4 1.7 1.5 8.7 0.1 2.1 1 1 1 2 2 2 0 Zn-ribbon containing protein (DUF2072) Zn_ribbon_recom PF13408.1 KUM56963.1 - 0.11 12.7 7.3 0.36 11.1 0.0 2.8 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain C1_1 PF00130.17 KUM56963.1 - 0.12 12.1 2.2 0.22 11.2 0.1 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-trcl PF13451.1 KUM56963.1 - 0.36 10.5 5.4 3.1 7.5 0.1 3.2 3 0 0 3 3 3 0 Probable zinc-binding domain Lar_restr_allev PF14354.1 KUM56963.1 - 0.62 10.4 8.1 3.5 8.0 0.3 3.1 1 1 2 3 3 3 0 Restriction alleviation protein Lar A2L_zn_ribbon PF08792.5 KUM56963.1 - 0.99 8.9 6.4 18 4.9 0.1 3.6 3 0 0 3 3 3 0 A2L zinc ribbon domain TF_Zn_Ribbon PF08271.7 KUM56963.1 - 2.2 7.6 7.7 6.4 6.1 0.1 3.2 3 0 0 3 3 3 0 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.6 KUM56963.1 - 3 7.5 8.6 0.77 9.4 0.3 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.1 KUM56963.1 - 7.3 5.9 9.9 14 5.0 0.0 3.7 3 1 1 4 4 4 0 zinc-ribbon domain IBR PF01485.16 KUM56963.1 - 7.8 6.4 7.3 1.2 9.0 0.1 2.6 2 1 0 2 2 2 0 IBR domain HEAT_2 PF13646.1 KUM56965.1 - 2.3e-28 98.2 2.8 2.3e-15 56.6 0.0 3.3 2 1 1 3 3 3 2 HEAT repeats HEAT_PBS PF03130.11 KUM56965.1 - 2.2e-16 58.5 0.7 0.011 16.1 0.2 6.6 8 0 0 8 8 8 4 PBS lyase HEAT-like repeat HEAT PF02985.17 KUM56965.1 - 2.2e-09 36.6 0.5 1.9 8.8 0.0 5.5 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 KUM56965.1 - 1.9e-07 31.3 2.6 0.17 12.3 0.0 4.7 3 2 1 4 4 4 4 HEAT-like repeat Cohesin_HEAT PF12765.2 KUM56965.1 - 0.0009 19.1 0.1 1 9.3 0.0 3.0 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion RuvA_C PF07499.8 KUM56965.1 - 0.052 13.7 3.7 3.8 7.7 0.1 3.2 4 0 0 4 4 4 0 RuvA, C-terminal domain PRK PF00485.13 KUM56966.1 - 5.6e-57 192.4 0.0 7.7e-57 191.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 KUM56966.1 - 8.1e-40 136.2 0.0 1.6e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 KUM56966.1 - 1.9e-08 35.1 0.0 5.7e-08 33.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KUM56966.1 - 2.9e-06 27.6 0.0 1.3e-05 25.5 0.0 2.1 3 0 0 3 3 3 1 AAA domain CPT PF07931.7 KUM56966.1 - 2.9e-05 23.7 0.0 6.9e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.7 KUM56966.1 - 0.0046 16.0 0.0 0.014 14.5 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 KUM56966.1 - 0.007 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Pribosyltran PF00156.22 KUM56966.1 - 0.014 15.1 0.0 0.23 11.1 0.0 2.4 2 0 0 2 2 2 0 Phosphoribosyl transferase domain DUF87 PF01935.12 KUM56966.1 - 0.017 14.9 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 APS_kinase PF01583.15 KUM56966.1 - 0.045 13.4 0.2 0.73 9.4 0.0 2.6 3 0 0 3 3 3 0 Adenylylsulphate kinase ABC_tran PF00005.22 KUM56966.1 - 0.12 12.6 0.4 0.48 10.7 0.1 2.0 2 0 0 2 2 2 0 ABC transporter NB-ARC PF00931.17 KUM56966.1 - 0.13 11.0 0.0 0.26 10.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain NUC153 PF08159.7 KUM56967.1 - 2.3e-10 39.8 8.8 1e-09 37.8 0.2 3.9 3 0 0 3 3 3 2 NUC153 domain p450 PF00067.17 KUM56968.1 - 6.2e-77 259.0 0.0 8.2e-77 258.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.3 KUM56969.1 - 1.9e-08 33.3 4.8 1.5e-07 30.3 0.3 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain adh_short PF00106.20 KUM56970.1 - 3.9e-06 26.8 0.0 6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM56970.1 - 0.0034 17.0 0.0 0.0078 15.8 0.0 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 KUM56971.1 - 1.1e-14 54.2 0.1 1.8e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KUM56971.1 - 1.6e-08 34.7 0.0 2.6e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KUM56971.1 - 0.065 13.5 0.3 0.19 12.0 0.2 2.0 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 KUM56971.1 - 0.078 12.6 0.9 4.2 6.9 0.1 2.8 2 1 1 3 3 3 0 KR domain Lep_receptor_Ig PF06328.6 KUM56973.1 - 0.26 11.2 3.1 0.79 9.6 2.1 1.7 1 1 0 1 1 1 0 Ig-like C2-type domain DUF747 PF05346.6 KUM56975.1 - 1.3e-127 425.4 2.4 1.8e-127 424.9 1.7 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family PduL PF06130.7 KUM56976.1 - 0.099 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Propanediol utilisation protein PduL Curto_V2 PF07325.6 KUM56976.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Curtovirus V2 protein PNP_UDP_1 PF01048.15 KUM56977.1 - 1.7e-37 128.6 0.1 2.1e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily TelA PF05816.6 KUM56978.1 - 0.088 11.4 0.4 0.13 10.9 0.3 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) DUF4291 PF14124.1 KUM56979.1 - 1.1e-76 256.5 0.1 1.2e-76 256.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Epimerase PF01370.16 KUM56980.1 - 1.4e-14 54.1 0.0 2e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KUM56980.1 - 4.2e-14 51.9 0.0 5.6e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KUM56980.1 - 1.8e-10 41.1 0.0 2.8e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KUM56980.1 - 3.4e-08 32.7 0.1 1.3e-05 24.3 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KUM56980.1 - 8.3e-05 21.9 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 KUM56980.1 - 0.00012 21.0 0.0 0.00018 20.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KUM56980.1 - 0.018 14.9 0.4 0.082 12.8 0.3 2.0 1 1 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 KUM56980.1 - 0.02 13.7 0.0 0.32 9.8 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain DapB_N PF01113.15 KUM56980.1 - 0.045 13.6 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 KUM56980.1 - 0.062 12.9 0.2 4.1 7.0 0.1 2.2 2 0 0 2 2 2 0 KR domain HrpB1_HrpK PF09613.5 KUM56980.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) TAFII55_N PF04658.8 KUM56981.1 - 5.9e-50 168.9 0.0 1.4e-49 167.7 0.0 1.6 1 0 0 1 1 1 1 TAFII55 protein conserved region IncA PF04156.9 KUM56981.1 - 1.8 8.1 11.3 0.29 10.7 5.0 1.7 2 0 0 2 2 2 0 IncA protein Ofd1_CTDD PF10637.4 KUM56982.1 - 4.6e-102 340.6 0.0 1.1e-95 319.7 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 KUM56982.1 - 2.5e-15 56.8 0.0 5.3e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.2 KUM56983.1 - 2.2e-19 69.5 0.3 1.6e-06 28.3 0.1 4.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KUM56983.1 - 1.1e-12 48.1 6.2 0.21 12.1 0.0 7.8 7 1 1 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.25 KUM56983.1 - 6.1e-12 44.7 6.3 0.42 10.5 0.3 7.3 6 1 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.1 KUM56983.1 - 1.7e-07 30.7 9.5 4 7.9 0.1 8.5 9 0 0 9 9 9 2 Ankyrin repeat Ank_5 PF13857.1 KUM56983.1 - 2.1e-06 27.7 8.5 1.2 9.4 0.0 8.3 5 3 3 8 8 8 1 Ankyrin repeats (many copies) ECH PF00378.15 KUM56985.1 - 1.1e-19 70.6 0.0 1.2e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KUM56985.1 - 0.0049 16.6 0.0 1.2 8.9 0.0 2.4 2 1 0 2 2 2 2 Peptidase family S49 ADH_zinc_N PF00107.21 KUM56986.1 - 1.5e-24 85.9 0.1 2.3e-24 85.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM56986.1 - 5.6e-21 74.3 1.3 1e-20 73.5 0.3 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KUM56986.1 - 0.012 16.5 0.0 0.026 15.3 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase MinC_N PF05209.8 KUM56986.1 - 0.02 14.6 0.0 0.066 12.9 0.0 1.8 2 0 0 2 2 2 0 Septum formation inhibitor MinC, N-terminal domain DUF4045 PF13254.1 KUM56991.1 - 6.2 5.9 12.6 6.5 5.9 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Raftlin PF15250.1 KUM56991.1 - 9.7 4.5 13.5 10 4.4 9.3 1.2 1 0 0 1 1 1 0 Raftlin MIP-T3 PF10243.4 KUM56991.1 - 9.9 4.5 33.6 11 4.3 23.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Methyltransf_26 PF13659.1 KUM56992.1 - 6.9e-12 45.4 0.0 1.4e-11 44.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM56992.1 - 6.2e-09 35.6 0.0 1.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM56992.1 - 3.4e-07 30.8 0.0 5e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KUM56992.1 - 6.5e-06 25.6 0.0 0.0013 18.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KUM56992.1 - 0.00027 21.2 0.0 0.0005 20.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_10 PF05971.7 KUM56992.1 - 0.0039 16.3 0.0 0.029 13.5 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF890) Ubie_methyltran PF01209.13 KUM56992.1 - 0.0042 16.2 0.0 0.0061 15.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 KUM56992.1 - 0.03 14.0 0.0 0.076 12.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.13 KUM56992.1 - 0.038 13.5 0.0 6.9 6.1 0.0 2.3 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 PrmA PF06325.8 KUM56992.1 - 0.039 13.0 0.0 0.054 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 KUM56992.1 - 0.075 12.7 0.0 0.13 11.9 0.0 1.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 KUM56992.1 - 0.1 13.0 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain N6_Mtase PF02384.11 KUM56992.1 - 0.16 11.0 0.0 0.94 8.4 0.0 1.9 1 1 0 1 1 1 0 N-6 DNA Methylase Asp PF00026.18 KUM56993.1 - 2.6e-69 233.9 9.6 3.1e-69 233.6 6.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KUM56993.1 - 3.1e-08 33.7 6.1 7.6e-08 32.4 3.2 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KUM56993.1 - 2.6e-07 31.0 2.1 0.0065 16.9 0.5 3.6 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KUM56993.1 - 4.1e-06 26.4 0.2 4.6e-05 23.0 0.0 2.5 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 KUM56993.1 - 0.0019 18.0 0.1 3 7.7 0.0 2.9 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Fcf2 PF08698.6 KUM56994.1 - 1.7e-31 108.1 1.5 2.3e-31 107.7 0.2 1.9 1 1 1 2 2 2 1 Fcf2 pre-rRNA processing CBFD_NFYB_HMF PF00808.18 KUM56995.1 - 4.3e-13 49.1 0.2 6.4e-13 48.5 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KUM56995.1 - 2.2e-08 34.1 0.1 3.3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 KUM56995.1 - 0.025 14.3 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Etmic-2 PF06670.6 KUM56995.1 - 0.059 12.0 0.0 0.072 11.7 0.0 1.1 1 0 0 1 1 1 0 Microneme protein Etmic-2 Sec15 PF04091.7 KUM56996.1 - 6e-116 387.1 2.8 1.4e-115 385.9 1.9 1.6 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Sec5 PF15469.1 KUM56996.1 - 0.00079 19.2 8.0 0.0012 18.5 1.0 3.2 2 1 1 3 3 3 1 Exocyst complex component Sec5 COG2 PF06148.6 KUM56996.1 - 0.0025 17.6 1.7 0.0025 17.6 1.2 2.8 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.4 KUM56996.1 - 0.0053 16.7 2.7 0.0053 16.7 1.8 2.9 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Sec8_exocyst PF04048.9 KUM56996.1 - 0.0095 15.5 1.3 0.0095 15.5 0.9 3.2 4 0 0 4 4 4 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 KUM56996.1 - 0.1 11.4 9.4 0.008 15.1 2.5 1.9 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) PNP_UDP_1 PF01048.15 KUM56998.1 - 1.6e-24 86.1 0.0 1.8e-24 86.0 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily PNP_UDP_1 PF01048.15 KUM56999.1 - 1.4e-12 47.1 0.3 2.2e-12 46.4 0.2 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily WD40 PF00400.27 KUM57000.1 - 9.1e-74 240.9 9.5 2.7e-12 46.0 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 KUM57000.1 - 2.6e-26 91.6 11.1 3.9e-26 91.0 7.7 1.3 1 0 0 1 1 1 1 Tup N-terminal Cytochrom_D1 PF02239.11 KUM57000.1 - 3.2e-05 22.3 0.4 0.00058 18.2 0.2 2.5 1 1 1 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.6 KUM57000.1 - 0.00016 21.4 0.0 0.0094 15.6 0.0 2.8 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KUM57000.1 - 0.00032 18.9 0.2 0.16 10.1 0.0 2.9 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 KUM57000.1 - 0.026 13.6 0.0 4.9 6.1 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 KUM57000.1 - 0.21 10.2 0.1 4.5 5.9 0.0 2.7 1 1 1 3 3 3 0 Nup133 N terminal like DUF4558 PF15104.1 KUM57000.1 - 0.88 9.5 4.6 1.7 8.5 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4558) FA_hydroxylase PF04116.8 KUM57001.1 - 5.3e-13 49.3 23.1 1.1e-12 48.3 12.3 2.3 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily zf-DHHC PF01529.15 KUM57001.1 - 0.16 11.3 1.9 0.42 10.0 1.3 1.8 1 1 0 1 1 1 0 DHHC palmitoyltransferase tRNA-synt_1b PF00579.20 KUM57002.1 - 7.7e-73 245.1 0.0 1e-72 244.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Ribosomal_S10 PF00338.17 KUM57003.1 - 1.1e-25 89.3 0.0 1.7e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Spc7_N PF15402.1 KUM57003.1 - 3.7 5.4 6.0 4.7 5.0 4.1 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 MCPVI PF02993.9 KUM57003.1 - 5.3 7.1 9.6 8.7 6.4 6.7 1.3 1 0 0 1 1 1 0 Minor capsid protein VI WD40 PF00400.27 KUM57004.1 - 1.1e-54 180.4 22.1 1.3e-12 47.1 0.2 12.2 13 0 0 13 13 13 7 WD domain, G-beta repeat Utp12 PF04003.7 KUM57004.1 - 4e-29 100.7 0.0 6.5e-29 100.0 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 KUM57004.1 - 2.3e-07 30.6 4.0 0.013 15.2 0.0 6.7 6 2 1 8 8 8 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KUM57004.1 - 1.1e-06 27.0 5.9 0.68 7.9 0.0 5.4 2 2 3 5 5 5 3 Nucleoporin Nup120/160 Nbas_N PF15492.1 KUM57004.1 - 0.0025 16.9 0.3 2.9 6.9 0.0 3.4 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal DUF1513 PF07433.6 KUM57004.1 - 0.02 13.7 0.2 2.9 6.7 0.0 3.5 2 2 0 3 3 3 0 Protein of unknown function (DUF1513) Coatomer_WDAD PF04053.9 KUM57004.1 - 0.041 12.6 0.0 5.8 5.5 0.0 3.1 3 1 1 4 4 4 0 Coatomer WD associated region PQQ_3 PF13570.1 KUM57004.1 - 0.44 10.8 6.8 2.2 8.6 0.1 5.0 6 0 0 6 6 6 0 PQQ-like domain ATP-synt_B PF00430.13 KUM57006.1 - 1.7 8.4 12.2 0.3 10.9 3.2 2.3 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) RR_TM4-6 PF06459.7 KUM57006.1 - 4.2 7.1 15.1 0.2 11.5 2.5 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Pkinase PF00069.20 KUM57007.1 - 7.1e-69 231.8 0.0 1.1e-68 231.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM57007.1 - 6.9e-35 120.3 0.0 1.3e-34 119.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM57007.1 - 0.0012 17.8 0.0 0.0026 16.7 0.0 1.5 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 KUM57007.1 - 0.036 13.1 0.1 0.075 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GTP_cyclohydroI PF01227.17 KUM57008.1 - 4.9e-73 244.2 0.6 6.8e-73 243.7 0.4 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 KUM57008.1 - 0.005 16.7 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 QueF-like protein WD40 PF00400.27 KUM57009.1 - 3.2e-42 140.9 7.6 1.3e-09 37.5 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KUM57009.1 - 8.6e-30 102.4 0.6 1.9e-29 101.3 0.4 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nup160 PF11715.3 KUM57009.1 - 0.0022 16.2 2.4 1 7.4 0.0 3.5 2 1 2 4 4 4 2 Nucleoporin Nup120/160 XRN_N PF03159.13 KUM57010.1 - 2.1e-103 344.8 0.0 4.2e-103 343.8 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus p450 PF00067.17 KUM57011.1 - 2.5e-32 111.9 0.0 9e-32 110.1 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 LptC PF06835.8 KUM57012.1 - 0.14 11.5 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide-assembly, LptC-related MTHFR_C PF12225.3 KUM57013.1 - 0.026 14.0 1.0 0.064 12.7 0.7 1.5 1 1 0 1 1 1 0 Methylene-tetrahydrofolate reductase C terminal MFS_1 PF07690.11 KUM57014.1 - 2.4e-21 75.8 20.4 2.4e-21 75.8 14.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Dimer_Tnp_hAT PF05699.9 KUM57015.1 - 4.2e-12 45.5 0.0 3.9e-11 42.4 0.0 2.3 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region IncA PF04156.9 KUM57015.1 - 0.78 9.3 7.7 1.5 8.3 5.3 1.4 1 0 0 1 1 1 0 IncA protein Sugar_tr PF00083.19 KUM57016.1 - 5.5e-66 223.0 26.0 6.3e-66 222.8 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM57016.1 - 1.6e-09 36.9 37.8 2.5e-09 36.3 21.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KUM57016.1 - 0.00014 20.4 4.9 0.00014 20.4 3.4 3.2 2 2 0 3 3 3 2 MFS/sugar transport protein BNR_2 PF13088.1 KUM57017.1 - 3.5e-29 101.9 1.1 1e-28 100.4 0.7 1.6 1 1 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 KUM57017.1 - 4.3e-09 34.8 24.5 0.09 12.6 0.1 6.2 6 0 0 6 6 6 5 BNR/Asp-box repeat Peptidase_M24 PF00557.19 KUM57018.1 - 1.1e-42 145.9 0.0 1.8e-42 145.2 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KUM57018.1 - 5e-07 30.2 0.0 1e-06 29.2 0.0 1.6 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Sugar_tr PF00083.19 KUM57019.1 - 2e-31 109.0 33.6 2.6e-17 62.5 8.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KUM57019.1 - 1.4e-25 89.7 48.3 8e-13 47.8 12.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KUM57019.1 - 8.9e-10 37.5 24.5 2.6e-06 26.0 6.0 3.2 1 1 2 3 3 3 3 MFS/sugar transport protein Hydrophobin PF01185.13 KUM57020.1 - 0.0004 20.7 4.4 0.001 19.4 2.9 1.7 1 1 0 1 1 1 1 Fungal hydrophobin NAD_binding_1 PF00175.16 KUM57021.1 - 1.2e-24 86.9 0.0 1.9e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KUM57021.1 - 3.3e-16 59.2 0.0 5.6e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KUM57021.1 - 1.7e-07 31.2 0.0 2.1e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KUM57021.1 - 0.046 13.6 0.0 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Aldo_ket_red PF00248.16 KUM57022.1 - 4.2e-63 212.8 0.0 5.1e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HMG_CoA_synt_C PF08540.5 KUM57023.1 - 1.9e-97 326.1 1.7 2.3e-97 325.8 1.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KUM57023.1 - 4e-87 290.2 0.1 5.9e-87 289.6 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Mur_ligase_C PF02875.16 KUM57023.1 - 0.093 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain DUF3197 PF11432.3 KUM57023.1 - 0.095 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3197) bZIP_1 PF00170.16 KUM57024.1 - 0.0014 18.5 9.6 0.0014 18.5 6.6 1.9 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KUM57024.1 - 0.69 9.7 11.5 0.059 13.1 3.8 2.1 2 0 0 2 2 2 0 Basic region leucine zipper eIF-3_zeta PF05091.7 KUM57025.1 - 4e-191 636.1 0.0 4.7e-191 635.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3546 PF12066.3 KUM57026.1 - 2.8e-25 88.4 1.4 2.8e-25 88.4 1.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) DUF4187 PF13821.1 KUM57026.1 - 3.6e-23 80.9 0.1 8.1e-23 79.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.8 KUM57026.1 - 4.6e-10 40.0 0.5 4.6e-10 40.0 0.3 2.1 2 1 0 2 2 2 1 Arsenite-resistance protein 2 Cnd1_N PF12922.2 KUM57026.1 - 1.3 8.6 4.6 4.1 6.9 1.1 2.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term PAD_porph PF04371.10 KUM57028.1 - 1.6e-70 237.7 0.0 2.9e-69 233.6 0.0 2.0 1 1 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase DUF881 PF05949.7 KUM57028.1 - 0.039 13.3 0.1 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF881) MFS_1 PF07690.11 KUM57029.1 - 6e-41 140.3 38.8 3.7e-31 108.1 14.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L13 PF00572.13 KUM57031.1 - 1.4e-42 144.7 0.0 2e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 Uricase PF01014.13 KUM57033.1 - 7.7e-85 281.9 1.2 7.5e-48 162.1 0.3 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.14 KUM57033.1 - 0.0028 17.3 0.0 0.0068 16.0 0.0 1.6 2 0 0 2 2 2 1 Plasmid recombination enzyme Phos_pyr_kin PF08543.7 KUM57034.1 - 1.4e-82 276.6 0.4 1.8e-82 276.2 0.3 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 KUM57034.1 - 1.1e-50 172.3 0.3 1.5e-50 171.9 0.2 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 KUM57034.1 - 7e-09 35.2 0.1 1.1e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.12 KUM57034.1 - 0.00016 21.0 1.2 0.00041 19.6 0.2 1.9 2 0 0 2 2 2 1 Carbohydrate kinase HK PF02110.10 KUM57034.1 - 0.00065 18.9 0.6 0.083 12.0 0.1 2.3 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family TroA PF01297.12 KUM57034.1 - 0.16 11.1 0.1 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Periplasmic solute binding protein family Ribosomal_S9 PF00380.14 KUM57036.1 - 6.9e-40 136.0 1.1 7.8e-40 135.9 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DNA_pol_B PF00136.16 KUM57037.1 - 1e-115 387.1 4.0 1.9e-115 386.2 2.8 1.5 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 KUM57037.1 - 8.7e-67 224.1 1.1 1.8e-66 223.1 0.8 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 KUM57037.1 - 3.4e-39 134.6 0.0 1.3e-38 132.7 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 KUM57037.1 - 8.6e-24 83.1 14.2 1.2e-23 82.7 5.7 3.0 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal DUF4451 PF14616.1 KUM57037.1 - 0.0026 17.5 1.0 0.0065 16.2 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) DEAD PF00270.24 KUM57038.1 - 6.1e-44 149.4 0.1 1.2e-43 148.5 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM57038.1 - 2.8e-21 75.1 0.0 6.5e-21 73.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KUM57038.1 - 1.9e-20 72.1 0.0 3.5e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 KUM57038.1 - 0.058 13.2 0.0 0.27 11.0 0.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PNP_UDP_1 PF01048.15 KUM57039.1 - 5.3e-07 28.8 0.1 7.7e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily Antiterm PF03589.8 KUM57039.1 - 0.037 14.1 0.0 0.054 13.5 0.0 1.2 1 0 0 1 1 1 0 Antitermination protein HAD_2 PF13419.1 KUM57040.1 - 5.6e-05 23.4 0.0 0.00038 20.7 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KUM57040.1 - 0.00015 22.2 0.1 0.12 12.7 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KUM57040.1 - 0.0042 17.2 0.0 0.0053 16.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 KUM57040.1 - 0.089 12.6 0.0 0.21 11.5 0.0 1.6 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF1970 PF09301.5 KUM57040.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) TRP PF06011.7 KUM57041.1 - 3.5e-158 526.7 19.9 5.3e-158 526.1 13.8 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KUM57041.1 - 8.7e-40 136.0 0.0 1.4e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 ML-like domain gpUL132 PF11359.3 KUM57041.1 - 0.017 14.4 0.0 0.039 13.2 0.0 1.6 1 0 0 1 1 1 0 Glycoprotein UL132 DUF843 PF05814.6 KUM57041.1 - 0.68 9.7 8.8 6.3 6.6 0.1 3.4 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) OppC_N PF12911.2 KUM57041.1 - 1.7 8.0 0.0 1.7 8.0 0.0 3.7 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C Flavin_Reduct PF01613.13 KUM57044.1 - 7.8e-26 90.7 0.0 1.1e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Acetyltransf_3 PF13302.1 KUM57046.1 - 3.1e-14 53.3 0.0 4.1e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KUM57046.1 - 1.5e-11 44.1 0.0 2.1e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KUM57046.1 - 9e-08 32.1 0.0 1.5e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KUM57046.1 - 1.7e-06 28.0 0.0 2.7e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KUM57046.1 - 0.00037 20.5 0.0 0.00061 19.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CBM_21 PF03370.8 KUM57047.1 - 1.6e-36 124.6 0.3 3.1e-36 123.8 0.2 1.5 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Histone PF00125.19 KUM57048.1 - 1.9e-15 56.7 0.3 2.3e-15 56.4 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KUM57048.1 - 4.9e-05 23.4 0.1 6.6e-05 23.0 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 KUM57048.1 - 7.1e-05 22.6 0.2 0.0001 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 KUM57048.1 - 0.00011 22.2 0.1 0.00019 21.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KUM57048.1 - 0.0026 17.4 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 KUM57048.1 - 0.011 14.9 0.0 0.012 14.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID_20kDa PF03847.8 KUM57048.1 - 0.049 13.9 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Fungal_trans_2 PF11951.3 KUM57049.1 - 7.6e-10 37.9 0.2 1.2e-09 37.2 0.0 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C3HC4 PF00097.20 KUM57050.1 - 1.6e-08 34.0 4.6 1.6e-08 34.0 3.2 4.5 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KUM57050.1 - 2e-07 30.9 5.8 2e-07 30.9 4.0 4.3 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) SH3_9 PF14604.1 KUM57050.1 - 3e-07 29.9 0.4 3e-07 29.9 0.3 1.8 2 0 0 2 2 2 1 Variant SH3 domain zf-RING_6 PF14835.1 KUM57050.1 - 1e-06 28.3 0.7 1e-06 28.3 0.5 2.6 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KUM57050.1 - 2.7e-05 23.9 5.9 2.7e-05 23.9 4.1 4.1 5 1 0 5 5 5 1 zinc finger of C3HC4-type, RING ZZ PF00569.12 KUM57050.1 - 3.6e-05 23.1 5.6 3.6e-05 23.1 3.9 3.8 3 0 0 3 3 3 2 Zinc finger, ZZ type zf-RING_UBOX PF13445.1 KUM57050.1 - 7.1e-05 22.4 2.0 0.00026 20.6 1.4 2.1 1 0 0 1 1 1 1 RING-type zinc-finger SH3_1 PF00018.23 KUM57050.1 - 0.0031 16.8 0.3 0.007 15.7 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KUM57050.1 - 0.0092 15.4 0.1 0.024 14.1 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain MIP PF00230.15 KUM57053.1 - 1.9e-52 177.9 7.1 2.5e-52 177.6 4.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein FGGY_C PF02782.11 KUM57054.1 - 5.1e-72 241.6 0.2 8.6e-72 240.9 0.2 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KUM57054.1 - 2.3e-66 223.6 0.0 3.2e-66 223.1 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 KUM57054.1 - 0.074 12.3 0.1 3.4 6.8 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family p450 PF00067.17 KUM57055.1 - 5.1e-60 203.3 0.0 6.7e-60 202.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SopA PF13981.1 KUM57055.1 - 0.12 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 SopA-like central domain zf-CCCH_2 PF14608.1 KUM57056.1 - 8.9e-11 41.3 56.0 2.8e-06 27.1 7.4 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 KUM57056.1 - 0.0028 17.7 0.0 0.0048 16.9 0.0 1.3 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Peptidase_C58 PF03543.9 KUM57056.1 - 0.092 12.2 0.4 0.67 9.4 0.0 2.1 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen Mago-bind PF09282.5 KUM57058.1 - 4.5e-14 51.7 3.5 8.1e-14 50.8 2.4 1.5 1 0 0 1 1 1 1 Mago binding Amino_oxidase PF01593.19 KUM57059.1 - 8.1e-22 77.9 0.0 1.1e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KUM57059.1 - 4.1e-13 49.1 0.5 6.4e-12 45.3 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KUM57059.1 - 5.8e-05 22.1 0.0 0.00015 20.7 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KUM57059.1 - 0.022 14.5 0.0 0.36 10.5 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 KUM57059.1 - 0.022 13.8 0.1 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase zf-UBR PF02207.15 KUM57060.1 - 3.6e-17 61.8 14.9 9.3e-17 60.5 10.3 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) zf-RING_2 PF13639.1 KUM57060.1 - 8.4e-05 22.3 1.7 8.4e-05 22.3 1.2 4.7 4 1 0 4 4 4 1 Ring finger domain ClpS PF02617.12 KUM57060.1 - 0.00053 19.6 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-C3HC4_2 PF13923.1 KUM57060.1 - 0.0017 18.3 1.0 0.0017 18.3 0.7 4.0 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) Nop14 PF04147.7 KUM57060.1 - 1 7.1 8.0 2 6.2 5.6 1.4 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 KUM57060.1 - 8 5.3 6.5 15 4.4 4.5 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit UCR_UQCRX_QCR9 PF05365.7 KUM57061.1 - 1.2e-24 85.6 2.3 1.4e-24 85.4 1.6 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF4203 PF13886.1 KUM57061.1 - 0.072 12.5 0.0 0.072 12.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) Glyco_hydro_16 PF00722.16 KUM57063.1 - 1.5e-34 118.9 7.0 1.5e-34 118.9 4.9 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Bromo_TP PF07524.8 KUM57064.1 - 9.1e-07 28.5 0.0 1.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Glyco_hydro_16 PF00722.16 KUM57066.1 - 1.5e-33 115.6 5.4 1.7e-22 79.6 1.5 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 NDUFB10 PF10249.4 KUM57069.1 - 0.0033 17.5 0.0 0.0041 17.2 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 BRO1 PF03097.13 KUM57070.1 - 6.8e-07 28.3 0.0 1.2e-06 27.5 0.0 1.5 2 0 0 2 2 2 1 BRO1-like domain Pkinase PF00069.20 KUM57071.1 - 2.2e-69 233.5 0.0 3.2e-69 232.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM57071.1 - 3.2e-34 118.2 0.0 4.8e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KUM57071.1 - 3.6e-11 43.0 0.5 1.4e-10 41.1 0.3 2.0 2 0 0 2 2 2 1 FHA domain APH PF01636.18 KUM57071.1 - 7.8e-05 22.5 0.7 0.072 12.8 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 KUM57071.1 - 0.0009 18.3 0.1 0.0018 17.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KUM57071.1 - 0.021 13.7 0.0 0.083 11.8 0.0 1.8 1 1 0 1 1 1 0 Kinase-like Glyco_transf_34 PF05637.7 KUM57072.1 - 1.1e-63 214.8 0.4 1.6e-63 214.4 0.3 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Beta_elim_lyase PF01212.16 KUM57073.1 - 9.3e-69 231.7 0.0 1.2e-68 231.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 KUM57073.1 - 0.0003 19.2 0.0 0.00046 18.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.15 KUM57073.1 - 0.0022 16.6 0.0 0.004 15.7 0.0 1.3 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain GvpK PF05121.7 KUM57074.1 - 0.023 14.4 0.3 17 5.3 0.1 3.2 2 1 1 3 3 3 0 Gas vesicle protein K Yippee-Mis18 PF03226.9 KUM57074.1 - 0.21 11.6 1.5 0.47 10.5 1.1 1.6 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Peptidase_M50B PF13398.1 KUM57075.1 - 6e-57 192.2 22.8 7.6e-57 191.9 15.8 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.17 KUM57075.1 - 0.0047 15.9 0.2 0.0047 15.9 0.2 2.7 2 1 1 3 3 3 1 Peptidase family M50 Peptidase_M41 PF01434.13 KUM57075.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M41 YlaC PF10777.4 KUM57075.1 - 3.2 7.3 4.6 0.53 9.8 0.2 1.8 2 0 0 2 2 2 0 Inner membrane protein YlaC Metallophos PF00149.23 KUM57076.1 - 9.5e-44 149.1 0.7 1.2e-43 148.8 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UvdE PF03851.9 KUM57078.1 - 1.2e-112 375.4 0.0 1.7e-112 374.9 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE Nucleo_P87 PF07267.6 KUM57078.1 - 0.3 9.7 4.1 0.43 9.2 0.9 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 DUF2183 PF09949.4 KUM57079.1 - 6.9e-34 115.7 0.0 1.5e-33 114.6 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Acyl-CoA_dh_1 PF00441.19 KUM57080.1 - 1e-28 100.3 2.3 2e-28 99.3 1.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 KUM57080.1 - 2.3e-19 68.9 0.0 5.8e-19 67.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 KUM57080.1 - 5.7e-19 67.3 0.4 1.5e-18 66.0 0.2 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KUM57080.1 - 2.6e-06 27.9 0.0 7.5e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KUM57080.1 - 0.015 15.5 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain DUF2153 PF09921.4 KUM57080.1 - 0.017 14.6 0.0 0.043 13.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) PI31_Prot_N PF11566.3 KUM57081.1 - 1e-35 122.6 0.0 1.3e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 KUM57081.1 - 5.7e-18 65.3 17.5 5.7e-18 65.3 12.1 3.0 3 1 0 3 3 3 1 PI31 proteasome regulator Hexokinase_1 PF00349.16 KUM57082.1 - 2.2e-15 56.5 0.0 2.6e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Hexokinase MFS_1 PF07690.11 KUM57083.1 - 1.9e-22 79.4 72.0 1.2e-16 60.4 27.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_12 PF13424.1 KUM57085.1 - 1.4e-07 31.2 18.6 0.3 11.0 0.0 8.7 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 KUM57085.1 - 0.00011 21.7 5.2 4.9 7.1 0.0 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 KUM57085.1 - 0.09 12.7 18.3 16 5.6 0.0 7.9 9 0 0 9 9 9 0 Tetratricopeptide repeat E1_DerP2_DerF2 PF02221.10 KUM57087.1 - 2.3e-26 92.6 0.3 3.1e-26 92.2 0.2 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 KUM57087.1 - 9.2e-05 22.4 0.0 0.00029 20.8 0.0 1.8 1 1 0 1 1 1 1 ML-like domain DIM PF08194.7 KUM57087.1 - 0.22 11.5 0.8 0.43 10.5 0.6 1.5 1 0 0 1 1 1 0 DIM protein ATP-synt_F PF01990.12 KUM57088.1 - 3.2e-31 107.5 0.0 3.6e-31 107.3 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF257 PF03192.8 KUM57088.1 - 0.1 11.8 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 DUF2418 PF10332.4 KUM57089.1 - 5.2e-37 126.1 0.3 1.2e-36 125.0 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) MTHFR PF02219.12 KUM57091.1 - 2.9e-115 384.3 0.0 4.2e-115 383.7 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase ArgK PF03308.11 KUM57091.1 - 0.12 11.1 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 ArgK protein Pribosyltran PF00156.22 KUM57092.1 - 4.9e-15 55.3 0.3 9.4e-15 54.4 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Alpha-amylase PF00128.19 KUM57093.1 - 1.2e-16 61.0 1.5 3.9e-16 59.3 0.1 2.5 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 KUM57093.1 - 4.6e-14 52.4 0.1 7.8e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 KUM57093.1 - 5.7e-05 23.2 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 KUM57093.1 - 6.8e-05 22.3 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Methyltransf_18 PF12847.2 KUM57094.1 - 2.4e-07 31.3 0.0 6.2e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM57094.1 - 6.3e-07 29.7 0.0 2.7e-06 27.7 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM57094.1 - 5.7e-06 26.1 0.0 7.8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM57094.1 - 1e-05 25.1 0.0 2.3e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM57094.1 - 0.00014 22.1 0.0 0.00095 19.4 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM57094.1 - 0.00022 21.6 0.0 0.00072 19.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KUM57094.1 - 0.0021 18.0 0.1 0.013 15.5 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KUM57094.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family FAD_binding_4 PF01565.18 KUM57095.1 - 7.7e-18 64.3 4.8 2e-17 62.9 3.3 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KUM57095.1 - 2.4e-11 43.3 0.5 4.7e-11 42.4 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cu_bind_like PF02298.12 KUM57096.1 - 0.026 14.3 0.4 0.061 13.1 0.3 1.8 1 1 0 1 1 1 0 Plastocyanin-like domain Med3 PF11593.3 KUM57096.1 - 0.83 8.8 3.4 1.1 8.4 2.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal VSP PF03302.8 KUM57097.1 - 0.00016 20.4 3.1 0.00022 20.0 2.2 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein EphA2_TM PF14575.1 KUM57097.1 - 0.097 13.0 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DDE_1 PF03184.14 KUM57098.1 - 8.1e-46 155.8 0.2 5e-45 153.3 0.0 2.2 2 1 1 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 KUM57098.1 - 1.6e-12 47.0 1.3 4.7e-12 45.5 0.1 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_29 PF13551.1 KUM57098.1 - 0.017 15.2 0.1 0.085 13.0 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix ILVD_EDD PF00920.16 KUM57099.1 - 4.1e-201 668.9 0.5 4.7e-201 668.7 0.4 1.0 1 0 0 1 1 1 1 Dehydratase family 5_nucleotid_C PF02872.13 KUM57099.1 - 0.017 15.0 0.0 0.075 13.0 0.0 2.1 2 0 0 2 2 2 0 5'-nucleotidase, C-terminal domain Acyl-CoA_dh_1 PF00441.19 KUM57100.1 - 3.3e-32 111.6 0.6 3.3e-32 111.6 0.4 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KUM57100.1 - 2.1e-18 66.9 0.2 5.2e-18 65.6 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KUM57100.1 - 2.1e-15 57.1 0.4 2.1e-15 57.1 0.3 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KUM57100.1 - 5.2e-13 48.3 0.2 1.3e-12 47.0 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DUF2281 PF10047.4 KUM57101.1 - 0.092 13.0 0.1 0.17 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) p450 PF00067.17 KUM57102.1 - 1.3e-30 106.3 0.0 1.6e-30 106.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aldo_ket_red PF00248.16 KUM57104.1 - 4.6e-41 140.4 0.0 5.7e-41 140.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Abhydrolase_6 PF12697.2 KUM57105.1 - 9.4e-25 87.8 0.4 1.2e-24 87.4 0.3 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM57105.1 - 2.3e-10 40.4 0.0 3.1e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KUM57105.1 - 0.0012 18.4 0.8 0.0017 17.9 0.6 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 KUM57105.1 - 0.022 14.3 0.0 0.053 13.1 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein Hydrolase_4 PF12146.3 KUM57105.1 - 0.089 12.6 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase PAS_4 PF08448.5 KUM57105.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 PAS fold Mito_carr PF00153.22 KUM57106.1 - 1.4e-36 124.0 5.1 1.3e-17 63.3 0.3 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein AA_permease PF00324.16 KUM57107.1 - 2.9e-89 299.5 42.8 3.4e-89 299.4 29.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KUM57107.1 - 1.8e-22 79.4 46.2 2.2e-22 79.2 32.0 1.0 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_2_C PF02836.12 KUM57108.1 - 2.8e-87 292.3 0.0 3.8e-87 291.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 KUM57108.1 - 2.4e-34 118.2 0.1 6.7e-34 116.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KUM57108.1 - 2.2e-10 40.9 0.4 6.9e-10 39.3 0.3 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 DUF4434 PF14488.1 KUM57108.1 - 3.1e-05 23.7 0.5 0.00015 21.5 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4434) Cellulase-like PF12876.2 KUM57108.1 - 0.035 14.5 0.0 0.088 13.2 0.0 1.7 1 0 0 1 1 1 0 Sugar-binding cellulase-like Big_5 PF13205.1 KUM57108.1 - 0.12 12.9 0.9 0.33 11.5 0.6 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain Glyco_hydro_2_N PF02837.13 KUM57109.1 - 2.1e-12 46.9 0.2 4.8e-12 45.7 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KUM57109.1 - 6.7e-12 45.8 0.0 1.6e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Aconitase PF00330.15 KUM57111.1 - 3.1e-69 233.6 0.0 1.5e-43 148.9 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KUM57111.1 - 1.8e-21 76.6 0.0 3e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Sugar_tr PF00083.19 KUM57112.1 - 9.9e-62 208.9 24.1 1.1e-61 208.7 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM57112.1 - 3e-29 101.8 49.5 7.8e-24 84.0 17.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KUM57112.1 - 5.1e-08 31.5 1.1 1.1e-07 30.4 0.7 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 KUM57113.1 - 2.2e-21 75.8 0.1 3.6e-21 75.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rad9_Rad53_bind PF08605.5 KUM57113.1 - 0.064 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Fungal Rad9-like Rad53-binding Pyr_redox_3 PF13738.1 KUM57114.1 - 1.9e-21 77.0 0.0 6.6e-21 75.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KUM57114.1 - 6.1e-18 64.3 0.5 2e-16 59.2 0.1 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KUM57114.1 - 3.2e-07 30.2 0.0 1.2e-06 28.4 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KUM57114.1 - 0.00032 19.7 0.0 0.015 14.2 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) S_locus_glycop PF00954.15 KUM57114.1 - 0.084 13.1 2.8 0.72 10.1 0.1 2.4 2 0 0 2 2 2 0 S-locus glycoprotein family NAD_binding_9 PF13454.1 KUM57114.1 - 0.15 11.8 0.2 3 7.6 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding Telomerase_RBD PF12009.3 KUM57115.1 - 1.3e-45 154.6 0.9 2.8e-45 153.5 0.6 1.6 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 KUM57115.1 - 1.5e-13 50.6 0.0 4.6e-13 49.0 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RhoGEF PF00621.15 KUM57116.1 - 5.6e-36 124.0 0.0 1.2e-35 123.0 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.13 KUM57116.1 - 9e-13 48.2 0.2 4.2e-12 46.0 0.1 2.1 2 0 0 2 2 2 1 BAR domain adh_short PF00106.20 KUM57117.1 - 1.1e-23 84.0 0.2 5.7e-23 81.6 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM57117.1 - 4.1e-17 62.7 0.3 1.5e-16 60.8 0.2 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM57117.1 - 5.4e-10 39.2 0.2 1.2e-09 38.0 0.0 1.6 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.5 KUM57117.1 - 0.00069 18.8 0.0 0.0014 17.8 0.0 1.5 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.10 KUM57117.1 - 0.0015 17.5 0.0 0.0023 16.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KUM57117.1 - 0.0096 16.0 0.4 0.038 14.0 0.3 2.0 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 KUM57117.1 - 0.0098 15.6 0.1 0.069 12.8 0.0 2.0 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ADH_zinc_N PF00107.21 KUM57117.1 - 0.032 13.7 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase E1-E2_ATPase PF00122.15 KUM57118.1 - 3.6e-49 166.8 4.5 3.6e-49 166.8 3.1 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KUM57118.1 - 4.6e-43 146.8 3.7 4.6e-43 146.8 2.6 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KUM57118.1 - 5.7e-32 111.8 0.0 2.5e-31 109.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KUM57118.1 - 3.9e-21 74.8 0.0 8.9e-21 73.6 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KUM57118.1 - 1.2e-12 48.4 0.0 3.8e-12 46.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KUM57118.1 - 2.4e-10 39.7 0.2 7.4e-10 38.1 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KUM57118.1 - 1.4e-05 24.8 0.1 8.1e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2207 PF09972.4 KUM57118.1 - 0.37 9.3 1.1 7.2 5.0 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Pkinase PF00069.20 KUM57119.1 - 1e-29 103.4 0.0 1.2e-23 83.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KUM57119.1 - 6.5e-16 58.1 0.0 1.2e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM57119.1 - 0.0055 15.7 0.0 0.0079 15.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RabGAP-TBC PF00566.13 KUM57120.1 - 1.4e-29 103.1 0.0 2.5e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Thioredox_DsbH PF03190.10 KUM57122.1 - 7e-72 240.4 0.1 1.1e-71 239.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 KUM57122.1 - 2.3e-08 33.9 0.0 4.8e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like C5-epim_C PF06662.8 KUM57122.1 - 0.014 14.7 0.9 5.6 6.2 0.4 2.8 3 0 0 3 3 3 0 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_88 PF07470.8 KUM57122.1 - 0.034 13.1 0.8 20 4.0 0.1 3.7 3 1 1 4 4 4 0 Glycosyl Hydrolase Family 88 Thioredoxin_2 PF13098.1 KUM57122.1 - 0.053 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain Glyco_hydro_9 PF00759.14 KUM57122.1 - 0.054 12.3 0.8 0.089 11.6 0.6 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 DUF1680 PF07944.7 KUM57122.1 - 0.12 10.6 0.4 5 5.2 0.1 2.2 2 0 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) Carn_acyltransf PF00755.15 KUM57123.1 - 4.5e-167 556.7 0.0 7e-151 503.2 0.0 2.1 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase Ligase_CoA PF00549.14 KUM57123.1 - 1.5e-34 118.8 0.5 2.6e-16 59.6 0.1 2.5 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.14 KUM57123.1 - 1.5e-17 63.8 0.2 3.4e-17 62.7 0.1 1.6 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.1 KUM57123.1 - 4.1e-10 39.4 0.0 2.4e-09 36.8 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 KUM57123.1 - 0.0084 16.2 0.6 0.025 14.7 0.1 2.1 2 0 0 2 2 2 1 CoA binding domain CAP PF00188.21 KUM57124.1 - 7.5e-18 65.2 1.7 1.4e-17 64.2 1.2 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Herpes_BLLF1 PF05109.8 KUM57124.1 - 0.17 9.8 30.2 0.22 9.4 20.9 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) RAP1 PF07218.6 KUM57124.1 - 2.9 5.8 6.9 3.7 5.5 4.8 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Velvet PF11754.3 KUM57125.1 - 2.8e-18 66.2 0.0 4.7e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Velvet factor MFS_1 PF07690.11 KUM57127.1 - 1.8e-18 66.3 48.9 4.4e-10 38.8 13.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KUM57127.1 - 0.32 11.0 8.2 3.2 7.8 0.0 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1228) LSM14 PF12701.2 KUM57128.1 - 3.7e-31 106.7 0.0 7.1e-31 105.8 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 KUM57128.1 - 4e-20 72.2 2.3 8e-20 71.3 1.6 1.5 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.1 KUM57128.1 - 8.1e-05 22.4 0.0 0.00025 20.8 0.0 1.8 2 0 0 2 2 2 1 Ataxin 2 SM domain WD40 PF00400.27 KUM57129.1 - 1.3e-27 94.5 1.8 2e-05 24.2 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Reg_prop PF07494.6 KUM57129.1 - 0.0011 18.7 0.0 0.45 10.7 0.0 3.0 2 0 0 2 2 2 1 Two component regulator propeller PQQ_2 PF13360.1 KUM57129.1 - 0.0038 16.7 1.4 0.054 12.9 0.1 2.7 1 1 2 3 3 3 1 PQQ-like domain Gmad1 PF10647.4 KUM57129.1 - 0.0056 16.1 0.0 0.15 11.4 0.0 2.2 2 0 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain PQQ_3 PF13570.1 KUM57129.1 - 0.011 16.0 0.2 7 7.0 0.0 4.1 4 0 0 4 4 4 0 PQQ-like domain Nup160 PF11715.3 KUM57129.1 - 0.011 13.9 0.0 0.045 11.8 0.0 1.9 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Sigma70_r1_2 PF00140.15 KUM57129.1 - 0.083 12.5 0.9 0.29 10.8 0.6 1.9 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 ADH_zinc_N PF00107.21 KUM57130.1 - 3.4e-16 58.9 0.0 5.8e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM57130.1 - 5.4e-14 51.8 0.2 9.3e-14 51.1 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KUM57130.1 - 1.7e-06 28.9 0.1 4.8e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KUM57130.1 - 0.0031 17.0 0.1 0.0055 16.2 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.20 KUM57131.1 - 2e-21 76.6 0.0 3.6e-21 75.7 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM57131.1 - 8.1e-10 38.6 0.0 7.7e-07 28.9 0.0 2.2 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 KUM57131.1 - 7.2e-06 25.9 0.0 0.0003 20.6 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KUM57131.1 - 0.00062 19.2 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KUM57131.1 - 0.11 11.1 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KUM57131.1 - 0.13 11.5 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Aa_trans PF01490.13 KUM57132.1 - 6.5e-28 97.3 34.9 8.2e-28 97.0 24.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 KUM57132.1 - 2.1e-10 39.7 43.0 4.4e-09 35.3 29.8 2.0 1 1 0 1 1 1 1 Amino acid permease TauD PF02668.11 KUM57133.1 - 1.6e-46 159.0 0.0 2e-46 158.8 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family OPT PF03169.10 KUM57134.1 - 2.2e-122 409.6 33.3 2.5e-122 409.4 23.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Lactamase_B PF00753.22 KUM57135.1 - 9.4e-09 35.1 0.2 1.3e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KUM57135.1 - 0.00092 18.7 0.0 0.0015 18.1 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain MFS_1 PF07690.11 KUM57136.1 - 3.6e-32 111.4 42.7 4e-32 111.3 27.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1129 PF06570.6 KUM57136.1 - 0.047 12.9 2.9 0.88 8.8 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) OSTbeta PF15048.1 KUM57136.1 - 0.16 12.0 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein SKG6 PF08693.5 KUM57136.1 - 1.1 8.6 5.2 4.1 6.7 3.6 2.0 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Baculo_11_kDa PF06143.6 KUM57136.1 - 6.6 6.1 7.0 2 7.8 0.0 2.9 3 0 0 3 3 3 0 Baculovirus 11 kDa family Pyr_redox_3 PF13738.1 KUM57137.1 - 3.1e-19 69.8 0.0 1.7e-17 64.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KUM57137.1 - 5.2e-18 64.5 0.0 8e-17 60.6 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KUM57137.1 - 2.9e-09 36.8 0.0 8.4e-09 35.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KUM57137.1 - 3.9e-07 29.2 0.0 2.7e-05 23.2 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KUM57137.1 - 0.0011 18.7 0.2 0.11 12.3 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 KUM57137.1 - 0.023 13.7 0.0 3 6.7 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Abhydrolase_3 PF07859.8 KUM57138.1 - 2.4e-51 174.3 0.0 3.2e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KUM57138.1 - 7.9e-17 61.1 0.2 5.9e-16 58.2 0.1 2.3 2 1 0 2 2 2 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KUM57138.1 - 5.2e-05 23.0 0.0 7.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KUM57138.1 - 0.0044 16.9 0.0 0.006 16.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KUM57138.1 - 0.038 13.2 0.0 0.33 10.1 0.0 2.3 2 1 0 2 2 2 0 Prolyl oligopeptidase family Snf7 PF03357.16 KUM57139.1 - 1.3e-20 73.5 9.4 1.3e-20 73.5 6.5 1.7 1 1 0 2 2 2 1 Snf7 PSD4 PF07631.6 KUM57139.1 - 0.072 13.4 0.8 0.22 11.9 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1592) BMFP PF04380.8 KUM57139.1 - 0.18 11.9 10.5 0.42 10.7 0.8 4.1 3 1 1 4 4 4 0 Membrane fusogenic activity T2SJ PF11612.3 KUM57139.1 - 0.36 10.5 5.2 0.3 10.7 2.6 1.5 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein J ING PF12998.2 KUM57139.1 - 5.5 7.3 6.6 9.2 6.5 2.0 2.8 1 1 3 4 4 4 0 Inhibitor of growth proteins N-terminal histone-binding Tnp_P_element_C PF12596.3 KUM57139.1 - 7.1 7.0 7.2 25 5.2 0.1 2.8 2 1 1 3 3 3 0 87kDa Transposase zf-CCCH PF00642.19 KUM57140.1 - 0.00019 21.0 3.0 0.00019 21.0 2.1 2.6 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HrpA_pilin PF09589.5 KUM57140.1 - 0.045 14.1 3.8 2.6 8.4 0.5 2.3 2 0 0 2 2 2 0 HrpA pilus formation protein WD40 PF00400.27 KUM57141.1 - 0.018 14.9 0.6 0.047 13.5 0.2 1.9 2 0 0 2 2 2 0 WD domain, G-beta repeat DAO PF01266.19 KUM57142.1 - 1.1e-18 67.2 0.0 1.5e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase CS PF04969.11 KUM57144.1 - 2.1e-09 37.8 0.0 3.3e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 CS domain Xol-1_GHMP-like PF09109.5 KUM57144.1 - 0.17 11.9 1.3 0.26 11.3 0.9 1.3 1 0 0 1 1 1 0 Switch protein XOL-1, GHMP-like LysM PF01476.15 KUM57145.1 - 1.6e-05 24.7 0.0 0.99 9.3 0.0 3.3 3 0 0 3 3 3 2 LysM domain NaeI PF09126.5 KUM57145.1 - 0.13 10.8 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease NaeI 2-Hacid_dh_C PF02826.14 KUM57146.1 - 1.4e-37 128.5 0.0 2.5e-37 127.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KUM57146.1 - 1.8e-20 72.7 0.0 2.4e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.7 KUM57146.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain XdhC_C PF13478.1 KUM57146.1 - 0.018 15.3 0.0 0.31 11.3 0.0 2.3 2 0 0 2 2 2 0 XdhC Rossmann domain AdoHcyase_NAD PF00670.16 KUM57146.1 - 0.024 14.4 2.5 0.035 13.9 0.4 2.2 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.16 KUM57146.1 - 0.081 12.4 4.3 2.8 7.4 0.1 2.8 2 1 1 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain EF-hand_8 PF13833.1 KUM57147.1 - 0.0017 17.9 0.0 0.33 10.6 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 KUM57147.1 - 0.0047 16.6 0.5 1.2 9.1 0.0 3.7 4 1 0 4 4 4 1 EF-hand domain RuvA_C PF07499.8 KUM57147.1 - 0.083 13.0 0.0 0.29 11.3 0.0 1.9 1 1 0 1 1 1 0 RuvA, C-terminal domain RRM_1 PF00076.17 KUM57148.1 - 8.8e-06 25.2 0.0 1.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KUM57148.1 - 1e-05 25.8 1.6 2e-05 24.9 1.1 1.5 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 KUM57148.1 - 7.6e-05 22.4 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM57148.1 - 0.0011 18.9 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CbiG_mid PF11761.3 KUM57148.1 - 0.027 14.6 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis central region Stm1_N PF09598.5 KUM57148.1 - 2.2 9.0 8.3 6.2 7.5 5.8 1.8 1 0 0 1 1 1 0 Stm1 PhzC-PhzF PF02567.11 KUM57149.1 - 5.9e-44 150.3 0.0 6.2e-30 104.3 0.0 2.0 2 0 0 2 2 2 2 Phenazine biosynthesis-like protein PUL PF08324.6 KUM57150.1 - 7.7e-39 133.0 0.0 1.3e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.9 KUM57150.1 - 1.1e-32 112.9 0.0 1.9e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.15 KUM57150.1 - 2.5e-15 56.0 0.0 4.9e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KUM57150.1 - 2.5e-05 24.4 0.2 0.00015 21.9 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 KUM57150.1 - 0.0023 17.6 0.0 0.0042 16.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_3 PF13192.1 KUM57150.1 - 0.0031 17.2 0.1 0.0098 15.6 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin domain TraF PF13728.1 KUM57150.1 - 0.019 14.4 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein DUF2847 PF11009.3 KUM57150.1 - 0.048 13.2 0.0 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2847) Redoxin PF08534.5 KUM57150.1 - 0.069 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Redoxin Thioredoxin_4 PF13462.1 KUM57150.1 - 0.18 11.7 0.2 0.58 10.1 0.1 1.7 1 1 1 2 2 2 0 Thioredoxin Macro PF01661.16 KUM57152.1 - 5.2e-10 39.2 0.0 5.6e-09 35.9 0.0 2.1 1 1 0 1 1 1 1 Macro domain Ribonuclease_T2 PF00445.13 KUM57153.1 - 5.6e-46 156.5 1.3 8.6e-46 155.9 0.9 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family MFS_1 PF07690.11 KUM57155.1 - 5.8e-37 127.2 36.2 3.7e-31 108.1 9.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KUM57155.1 - 1.1e-07 30.2 0.2 1.1e-07 30.2 0.1 1.6 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF334 PF03904.8 KUM57155.1 - 0.054 12.8 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Vma12 PF11712.3 KUM57155.1 - 0.073 12.7 0.2 3.6 7.2 0.0 2.5 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase BCNT PF07572.7 KUM57156.1 - 8.5e-26 89.7 1.5 8.5e-26 89.7 1.1 2.1 2 0 0 2 2 2 1 Bucentaur or craniofacial development TFIIF_alpha PF05793.7 KUM57156.1 - 0.0002 19.9 22.1 0.00031 19.2 15.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BTV_NS2 PF04514.7 KUM57156.1 - 7.2 5.3 11.3 15 4.3 7.8 1.5 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CENP-X PF09415.5 KUM57159.1 - 6.4e-29 99.5 0.0 1.2e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.18 KUM57159.1 - 0.0093 16.0 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2934 PF11154.3 KUM57159.1 - 0.011 15.1 0.4 0.02 14.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2934) Golgin_A5 PF09787.4 KUM57159.1 - 0.56 8.6 11.6 0.73 8.2 8.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 TFIIA PF03153.8 KUM57159.1 - 0.59 9.9 9.9 0.68 9.7 6.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S64 PF08192.6 KUM57159.1 - 2.2 6.5 7.2 2.9 6.1 5.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 Ndc1_Nup PF09531.5 KUM57159.1 - 2.2 6.5 12.3 2.9 6.2 8.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PIH1 PF08190.7 KUM57159.1 - 3.4 7.0 11.0 3.9 6.8 7.6 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 SOG2 PF10428.4 KUM57159.1 - 8.5 4.9 16.3 9.7 4.7 11.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein MIF PF01187.13 KUM57160.1 - 5.3e-06 26.4 0.0 1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Amidohydro_4 PF13147.1 KUM57161.1 - 2.4e-11 44.1 0.0 3.1e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 KUM57161.1 - 8.1e-06 25.5 0.0 1.5e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KUM57161.1 - 0.0066 16.1 0.0 0.027 14.1 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family Mis12 PF05859.7 KUM57162.1 - 1.6e-45 154.4 0.0 3.1e-45 153.5 0.0 1.5 1 0 0 1 1 1 1 Mis12 protein p450 PF00067.17 KUM57164.1 - 7.3e-104 347.8 0.0 8.2e-104 347.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 OPT PF03169.10 KUM57165.1 - 1.1e-185 618.7 57.6 1.2e-185 618.5 39.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein LSM PF01423.17 KUM57166.1 - 4.8e-15 54.8 0.6 6.9e-15 54.3 0.4 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KUM57166.1 - 0.0071 16.2 0.0 0.011 15.6 0.0 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain Abhydrolase_6 PF12697.2 KUM57167.1 - 1.3e-17 64.4 0.0 2e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM57167.1 - 1.8e-10 40.7 0.0 3.1e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM57167.1 - 7.6e-05 22.3 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DRMBL PF07522.9 KUM57168.1 - 1e-33 115.6 0.0 1.8e-33 114.8 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 KUM57168.1 - 8.4e-10 38.5 0.0 1.7e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KUM57168.1 - 0.065 12.8 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily TIP49 PF06068.8 KUM57168.1 - 0.36 9.5 0.3 0.58 8.8 0.2 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Bravo_FIGEY PF13882.1 KUM57168.1 - 0.44 11.4 4.8 1.5 9.7 3.3 2.0 1 0 0 1 1 1 0 Bravo-like intracellular region Methyltransf_11 PF08241.7 KUM57169.1 - 2.1e-08 34.5 0.0 4.2e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM57169.1 - 0.00012 21.8 0.0 0.00024 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Zn_clus PF00172.13 KUM57170.1 - 6.3e-08 32.4 10.8 6.3e-08 32.4 7.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNase_T PF00929.19 KUM57171.1 - 8.4e-21 74.9 0.0 2.2e-20 73.5 0.0 1.6 2 0 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.15 KUM57171.1 - 0.0068 15.8 0.0 0.032 13.7 0.0 2.1 1 1 0 1 1 1 1 3'-5' exonuclease Glyco_hydro_43 PF04616.9 KUM57172.1 - 8.2e-73 244.9 0.7 1.2e-72 244.4 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Sugar_tr PF00083.19 KUM57173.1 - 4.2e-72 243.1 23.7 4.9e-72 242.9 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM57173.1 - 5.6e-23 81.2 31.5 2.6e-16 59.2 7.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KUM57173.1 - 0.00065 18.0 4.1 0.00065 18.0 2.8 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) VHP PF02209.14 KUM57173.1 - 0.25 11.0 1.5 0.54 10.0 1.1 1.5 1 0 0 1 1 1 0 Villin headpiece domain ketoacyl-synt PF00109.21 KUM57175.1 - 1.4e-75 254.0 1.1 2.5e-75 253.2 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KUM57175.1 - 5.8e-57 192.2 0.0 1.5e-56 190.9 0.0 1.8 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 KUM57175.1 - 5.8e-56 190.1 0.1 1.1e-55 189.2 0.1 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KUM57175.1 - 9.3e-47 159.6 0.0 1.5e-46 158.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KUM57175.1 - 1.3e-42 145.6 0.0 2.9e-42 144.4 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KUM57175.1 - 1e-36 125.3 0.0 2.5e-36 124.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KUM57175.1 - 4.7e-06 26.7 0.1 2.8e-05 24.2 0.0 2.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KUM57175.1 - 0.003 16.5 0.0 0.0058 15.6 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 KUM57175.1 - 0.0036 16.9 0.5 0.014 15.0 0.1 2.2 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_N PF08240.7 KUM57175.1 - 0.021 14.5 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM57176.1 - 6.9e-11 41.8 0.1 1.7e-10 40.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM57176.1 - 1.3e-06 28.0 0.1 4.5e-06 26.3 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KUM57176.1 - 0.0073 17.2 0.0 0.23 12.3 0.0 2.5 2 1 0 2 2 2 1 Zinc-binding dehydrogenase DUF3021 PF11457.3 KUM57178.1 - 0.031 14.1 3.2 0.092 12.6 2.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) YfhO PF09586.5 KUM57178.1 - 1.7 6.5 4.9 2.3 6.1 3.4 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF4271 PF14093.1 KUM57178.1 - 5.3 6.6 14.1 5.2 6.6 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) Mpv17_PMP22 PF04117.7 KUM57179.1 - 3.6e-25 87.3 2.2 6.7e-25 86.5 1.5 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family IF4E PF01652.13 KUM57180.1 - 2.9e-59 199.3 0.5 3.5e-59 199.0 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Ribosomal_S5 PF00333.15 KUM57182.1 - 2e-27 94.7 1.6 5.5e-27 93.3 0.7 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 KUM57182.1 - 1.7e-21 75.2 0.1 3.4e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Eapp_C PF10238.4 KUM57183.1 - 0.056 13.3 0.6 0.058 13.2 0.4 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF2761 PF10959.3 KUM57183.1 - 0.1 12.2 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2761) BLVR PF06375.6 KUM57183.1 - 0.75 9.6 9.1 0.92 9.3 6.3 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Peptidase_S49_N PF08496.5 KUM57183.1 - 0.83 9.4 5.2 0.89 9.3 3.6 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PTR2 PF00854.16 KUM57184.1 - 1.3e-50 172.3 10.8 5.6e-49 166.8 7.5 2.2 1 1 0 1 1 1 1 POT family BolA PF01722.13 KUM57185.1 - 4.4e-29 100.2 2.8 6e-29 99.8 1.9 1.2 1 0 0 1 1 1 1 BolA-like protein SNARE PF05739.14 KUM57186.1 - 3.2e-10 39.5 4.4 3.2e-10 39.5 3.1 3.3 3 0 0 3 3 3 1 SNARE domain GP41 PF00517.12 KUM57186.1 - 0.022 14.3 1.3 0.022 14.3 0.9 2.4 2 0 0 2 2 2 0 Retroviral envelope protein Dispanin PF04505.7 KUM57186.1 - 0.027 14.0 0.4 0.057 12.9 0.3 1.5 1 0 0 1 1 1 0 Interferon-induced transmembrane protein DUF2951 PF11166.3 KUM57186.1 - 0.027 14.3 0.6 0.027 14.3 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2951) COG5 PF10392.4 KUM57186.1 - 0.033 14.1 9.5 0.046 13.6 0.2 3.3 3 1 0 3 3 3 0 Golgi transport complex subunit 5 NPV_P10 PF05531.7 KUM57186.1 - 0.058 13.6 5.2 1 9.6 0.0 3.3 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein VitD-bind_III PF09164.5 KUM57186.1 - 0.091 12.3 0.1 0.3 10.7 0.1 1.8 1 0 0 1 1 1 0 Vitamin D binding protein, domain III SLS PF14611.1 KUM57186.1 - 0.12 11.8 4.9 0.021 14.2 0.8 1.6 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator DUF3753 PF12575.3 KUM57186.1 - 0.14 12.0 1.5 0.29 10.9 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Fib_alpha PF08702.5 KUM57186.1 - 0.17 12.0 14.2 0.54 10.3 1.2 2.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Syntaxin_2 PF14523.1 KUM57186.1 - 0.18 11.8 14.9 0.31 11.0 4.3 3.2 2 2 0 2 2 2 0 Syntaxin-like protein DUF3153 PF11353.3 KUM57186.1 - 0.21 10.9 7.2 0.6 9.4 5.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3153) CDC37_N PF03234.9 KUM57186.1 - 0.32 11.2 9.5 1.8 8.8 2.3 2.2 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding RskA PF10099.4 KUM57186.1 - 0.41 10.3 4.0 0.13 11.9 0.7 1.8 2 0 0 2 2 2 0 Anti-sigma-K factor rskA COG2 PF06148.6 KUM57186.1 - 0.64 9.8 7.6 2.5 7.9 0.2 2.9 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Tweety PF04906.8 KUM57186.1 - 0.66 8.3 7.2 0.17 10.2 1.7 2.0 1 1 0 2 2 2 0 Tweety Hormone_1 PF00103.15 KUM57186.1 - 0.69 9.2 3.6 17 4.6 0.1 2.9 2 1 1 3 3 3 0 Somatotropin hormone family Laminin_II PF06009.7 KUM57186.1 - 1.1 9.0 14.8 1.7 8.3 2.6 3.2 2 1 1 3 3 3 0 Laminin Domain II Osmo_CC PF08946.5 KUM57186.1 - 1.7 8.7 5.7 7.7 6.6 0.1 3.2 3 0 0 3 3 3 0 Osmosensory transporter coiled coil Syntaxin PF00804.20 KUM57186.1 - 1.9 8.7 18.1 0.11 12.6 4.3 2.8 1 1 1 2 2 1 0 Syntaxin HisKA_3 PF07730.8 KUM57186.1 - 2 8.8 9.4 2.7 8.4 0.1 3.8 2 2 2 4 4 4 0 Histidine kinase ETRAMP PF09716.5 KUM57186.1 - 2.7 8.0 5.7 0.71 9.8 0.5 2.6 2 2 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF1664 PF07889.7 KUM57186.1 - 2.9 7.7 7.1 4.8 6.9 0.9 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Excalibur PF05901.6 KUM57187.1 - 0.028 14.7 6.2 54 4.2 0.0 5.2 5 0 0 5 5 5 0 Excalibur calcium-binding domain YpzI PF14140.1 KUM57187.1 - 0.13 11.7 17.2 4.1 6.9 0.0 5.3 5 0 0 5 5 5 0 YpzI-like protein AMP-binding PF00501.23 KUM57188.1 - 1.7e-65 221.0 0.0 2.3e-65 220.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KUM57188.1 - 1.5e-11 45.0 0.0 3.9e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Frag1 PF10277.4 KUM57189.1 - 1.8e-43 148.5 14.8 2.1e-43 148.3 10.3 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF3671 PF12420.3 KUM57189.1 - 0.043 13.7 0.6 0.043 13.7 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function DUF4006 PF13179.1 KUM57189.1 - 0.069 12.7 0.1 0.069 12.7 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF4006) DUF962 PF06127.6 KUM57189.1 - 0.19 11.6 1.7 6 6.8 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF962) DUF3087 PF11286.3 KUM57189.1 - 2.6 7.2 5.2 0.68 9.1 1.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3087) Na_Ca_ex PF01699.19 KUM57189.1 - 4.3 6.9 12.5 0.067 12.7 2.3 2.4 2 1 2 4 4 4 0 Sodium/calcium exchanger protein Presenilin PF01080.12 KUM57191.1 - 0.0054 15.6 0.3 0.006 15.4 0.2 1.0 1 0 0 1 1 1 1 Presenilin Glyco_hydro_18 PF00704.23 KUM57192.1 - 3.2e-70 237.2 10.1 3.2e-70 237.2 7.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KUM57192.1 - 5.4e-08 32.6 17.0 5.4e-08 32.6 11.8 3.7 2 0 0 2 2 2 1 Chitin recognition protein DNase_NucA_NucB PF14040.1 KUM57192.1 - 9.2e-07 29.0 0.3 9.3e-06 25.7 0.1 2.5 2 0 0 2 2 2 1 Deoxyribonuclease NucA/NucB LysM PF01476.15 KUM57193.1 - 4.4e-16 58.5 0.9 8.4e-08 31.9 0.0 4.1 4 0 0 4 4 4 3 LysM domain Chitin_bind_1 PF00187.14 KUM57193.1 - 0.0013 18.6 20.8 0.0013 18.6 14.4 3.8 6 0 0 6 6 6 1 Chitin recognition protein Myb_DNA-bind_6 PF13921.1 KUM57195.1 - 6.9e-05 22.8 0.0 8.3e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3836 PF12930.2 KUM57195.1 - 0.084 12.3 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF3836) Baculo_LEF-2 PF03041.9 KUM57197.1 - 0.011 15.4 0.3 0.013 15.1 0.2 1.1 1 0 0 1 1 1 0 lef-2 DUF500 PF04366.7 KUM57198.1 - 4.6e-43 145.6 0.4 1.1e-42 144.4 0.2 1.6 2 0 0 2 2 2 1 Family of unknown function (DUF500) SH3_1 PF00018.23 KUM57198.1 - 1.4e-13 50.0 0.2 4.6e-13 48.3 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 KUM57198.1 - 1.9e-12 46.4 0.2 4.5e-12 45.2 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 KUM57198.1 - 6.6e-11 41.6 0.0 1.3e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Smr PF01713.16 KUM57199.1 - 0.00043 20.4 0.2 0.0013 18.9 0.2 1.9 1 0 0 1 1 1 1 Smr domain CUE PF02845.11 KUM57199.1 - 0.042 13.3 0.1 0.09 12.2 0.1 1.6 1 0 0 1 1 1 0 CUE domain Zds_C PF08632.5 KUM57200.1 - 8.3e-31 105.1 1.6 1.4e-30 104.4 1.1 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Zn_clus PF00172.13 KUM57201.1 - 2.9e-09 36.6 11.4 4.8e-09 35.9 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Folate_carrier PF01770.13 KUM57201.1 - 0.1 11.1 0.0 0.17 10.3 0.0 1.3 1 0 0 1 1 1 0 Reduced folate carrier RTA1 PF04479.8 KUM57202.1 - 7.2e-20 71.4 2.1 1.1e-19 70.8 1.4 1.2 1 0 0 1 1 1 1 RTA1 like protein CATSPERB PF15149.1 KUM57202.1 - 0.2 9.8 0.1 0.38 8.8 0.1 1.4 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit beta protein family AAA_10 PF12846.2 KUM57203.1 - 3.5e-08 33.2 0.0 0.00032 20.2 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain AAA_22 PF13401.1 KUM57203.1 - 0.0012 18.9 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zot PF05707.7 KUM57203.1 - 0.0019 17.7 0.0 0.016 14.7 0.0 2.1 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA PF00004.24 KUM57203.1 - 0.0087 16.2 0.2 0.036 14.2 0.1 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 KUM57203.1 - 0.019 14.4 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Adeno_IVa2 PF02456.10 KUM57203.1 - 0.021 13.4 0.0 0.033 12.8 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Zeta_toxin PF06414.7 KUM57203.1 - 0.053 12.6 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin GPI-anchored PF10342.4 KUM57204.1 - 1.7e-17 63.6 1.5 1.7e-17 63.6 1.0 5.3 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family WD40 PF00400.27 KUM57205.1 - 2.6e-19 68.3 12.7 4e-06 26.4 0.2 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat IKI3 PF04762.7 KUM57205.1 - 1.8e-06 26.1 0.0 0.00034 18.5 0.0 2.0 1 1 1 2 2 2 2 IKI3 family Cytochrom_D1 PF02239.11 KUM57205.1 - 0.0092 14.3 0.0 0.017 13.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain eIF2A PF08662.6 KUM57205.1 - 0.022 14.5 0.1 0.1 12.2 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Miro PF08477.8 KUM57206.1 - 2.5e-38 131.2 0.0 6e-19 68.6 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 KUM57206.1 - 1.4e-34 117.7 0.0 2.4e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 KUM57206.1 - 6.5e-31 105.4 0.0 1.1e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 KUM57206.1 - 1.6e-24 86.1 0.0 2.2e-14 53.1 0.0 2.2 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 KUM57206.1 - 1.5e-10 41.0 0.0 0.00072 19.4 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.27 KUM57206.1 - 1.5e-07 30.1 1.1 0.0014 17.7 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KUM57206.1 - 5.7e-07 28.8 1.3 0.0012 18.4 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 KUM57206.1 - 7e-07 29.2 0.7 0.0007 19.6 0.1 2.9 3 0 0 3 3 2 1 EF-hand domain pair AAA_16 PF13191.1 KUM57206.1 - 1.9e-05 24.7 3.0 0.061 13.3 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KUM57206.1 - 1.9e-05 24.0 0.1 0.015 14.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KUM57206.1 - 3.7e-05 23.8 0.5 1.1 9.3 0.0 3.2 2 1 1 3 3 3 2 AAA domain EF-hand_8 PF13833.1 KUM57206.1 - 3.8e-05 23.2 0.8 0.045 13.3 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair AAA_28 PF13521.1 KUM57206.1 - 9.2e-05 22.4 0.1 0.034 14.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 KUM57206.1 - 0.00013 21.8 0.5 0.41 10.4 0.2 2.9 2 1 1 3 3 3 2 Dynamin family FtsK_SpoIIIE PF01580.13 KUM57206.1 - 0.00024 20.6 0.0 0.41 10.0 0.0 3.0 3 0 0 3 3 3 1 FtsK/SpoIIIE family GTP_EFTU PF00009.22 KUM57206.1 - 0.00027 20.4 0.1 0.59 9.5 0.1 3.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain EF-hand_5 PF13202.1 KUM57206.1 - 0.00028 20.0 2.6 0.014 14.7 0.2 2.6 2 0 0 2 2 2 1 EF hand AAA_25 PF13481.1 KUM57206.1 - 0.00094 18.6 0.0 1.5 8.1 0.0 2.9 3 0 0 3 3 3 2 AAA domain MobB PF03205.9 KUM57206.1 - 0.0014 18.3 0.1 0.27 10.9 0.2 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 KUM57206.1 - 0.0019 17.7 0.2 0.04 13.4 0.0 2.6 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 KUM57206.1 - 0.0025 18.1 0.1 3.2 8.0 0.0 2.8 2 2 0 2 2 2 1 AAA domain AAA_24 PF13479.1 KUM57206.1 - 0.0052 16.3 0.0 0.087 12.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KUM57206.1 - 0.0054 16.4 0.1 4.1 7.0 0.0 2.7 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 KUM57206.1 - 0.0054 16.8 0.0 0.95 9.6 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 KUM57206.1 - 0.0056 16.5 0.0 1.5 8.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KUM57206.1 - 0.0063 15.9 0.0 0.9 8.9 0.0 2.6 3 0 0 3 3 2 1 AAA-like domain ABC_tran PF00005.22 KUM57206.1 - 0.0086 16.3 0.0 5.2 7.3 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_17 PF13207.1 KUM57206.1 - 0.015 16.1 0.0 9.4 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KUM57206.1 - 0.017 14.2 0.1 1.3 8.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 SMC_N PF02463.14 KUM57206.1 - 0.025 13.8 0.1 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain cobW PF02492.14 KUM57206.1 - 0.026 13.9 1.1 1.3 8.4 0.1 3.6 4 1 0 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain IIGP PF05049.8 KUM57206.1 - 0.041 12.7 0.2 0.72 8.5 0.0 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) DUF815 PF05673.8 KUM57206.1 - 0.051 12.5 0.2 2 7.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_5 PF07728.9 KUM57206.1 - 0.067 12.9 0.7 26 4.5 0.0 3.1 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) Septin PF00735.13 KUM57206.1 - 0.086 11.8 0.0 1.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Septin ArgK PF03308.11 KUM57206.1 - 0.12 11.1 0.2 5.1 5.8 0.0 2.6 3 0 0 3 3 3 0 ArgK protein EF-hand_10 PF14788.1 KUM57206.1 - 0.13 11.9 0.6 0.62 9.7 0.1 2.1 2 0 0 2 2 2 0 EF hand Zeta_toxin PF06414.7 KUM57206.1 - 0.14 11.2 0.0 19 4.2 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Adeno_IVa2 PF02456.10 KUM57206.1 - 0.2 10.2 1.0 11 4.5 0.0 2.4 3 0 0 3 3 3 0 Adenovirus IVa2 protein AAA PF00004.24 KUM57206.1 - 0.2 11.8 1.4 15 5.7 0.1 3.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.4 KUM57206.1 - 0.21 10.1 0.0 15 4.0 0.0 2.3 2 1 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.1 KUM57206.1 - 0.22 11.8 0.2 35 4.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 KUM57206.1 - 0.27 10.7 1.7 32 3.9 0.0 3.4 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein Macoilin PF09726.4 KUM57208.1 - 8.4 4.5 17.5 9.4 4.3 12.2 1.0 1 0 0 1 1 1 0 Transmembrane protein Amidohydro_3 PF07969.6 KUM57210.1 - 1.2e-50 172.9 3.4 1.4e-50 172.7 2.4 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KUM57210.1 - 4.2e-12 45.7 0.1 1.3e-11 44.1 0.1 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KUM57210.1 - 6.5e-07 29.3 0.4 0.0052 16.4 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 KUM57210.1 - 0.018 15.0 11.8 0.032 14.2 1.3 3.0 1 1 1 2 2 2 0 Amidohydrolase MFS_1 PF07690.11 KUM57212.1 - 2.7e-29 101.9 34.5 2.7e-29 101.9 23.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3007 PF11460.3 KUM57212.1 - 0.2 11.7 2.4 0.55 10.3 1.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) FA_desaturase PF00487.19 KUM57214.1 - 1.4e-15 57.4 22.3 1.4e-15 57.4 15.5 1.9 1 1 1 2 2 2 2 Fatty acid desaturase DUF455 PF04305.9 KUM57215.1 - 5.3e-103 343.7 0.0 6.7e-103 343.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.21 KUM57215.1 - 7e-07 28.7 0.0 1.5e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 KUM57215.1 - 1.2e-06 28.1 0.0 3.1e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Arylsulfotran_2 PF14269.1 KUM57217.1 - 1.5e-43 149.0 0.3 3e-43 148.1 0.0 1.6 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KUM57217.1 - 1.9e-18 66.2 0.0 4e-18 65.2 0.0 1.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DUF1675 PF07897.6 KUM57218.1 - 0.74 9.6 9.3 0.89 9.3 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF1712 PF08217.6 KUM57218.1 - 1.2 7.2 4.1 1.4 7.0 2.8 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1712) TFIIA PF03153.8 KUM57218.1 - 9.6 5.9 7.6 12 5.6 5.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_11 PF00457.12 KUM57219.1 - 2.5e-76 255.0 23.3 3e-76 254.8 16.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 VacA2 PF03077.9 KUM57219.1 - 0.77 9.3 8.0 1.4 8.5 3.4 2.8 2 1 0 2 2 2 0 Putative vacuolating cytotoxin Ank_2 PF12796.2 KUM57220.1 - 4.9e-06 26.8 0.0 6.4e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KUM57220.1 - 6.1e-06 26.3 0.1 0.003 17.7 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KUM57220.1 - 7e-05 22.4 0.3 0.0099 15.6 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 KUM57220.1 - 0.00021 21.7 0.0 0.14 12.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM57220.1 - 0.0055 16.8 0.0 0.071 13.3 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Glyco_transf_90 PF05686.7 KUM57222.1 - 6.4e-32 110.7 0.0 9.1e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 KUM57222.1 - 0.00034 20.8 0.1 0.00063 19.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Kinesin PF00225.18 KUM57223.1 - 7.6e-111 370.0 0.0 1.1e-110 369.4 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 KUM57223.1 - 6.6e-43 145.7 0.2 1.4e-42 144.6 0.1 1.6 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 KUM57223.1 - 1.9e-07 31.2 0.0 6.2e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 PH domain KIF1B PF12423.3 KUM57223.1 - 3.4e-07 30.1 0.2 8.9e-07 28.8 0.2 1.8 1 0 0 1 1 1 1 Kinesin protein 1B PEP-utilisers_N PF05524.8 KUM57223.1 - 1.2 9.0 6.1 8.7 6.1 0.3 2.7 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal CBFB_NFYA PF02045.10 KUM57224.1 - 1.2e-30 105.7 4.1 2.3e-30 104.9 2.9 1.4 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.7 KUM57224.1 - 0.05 12.5 0.0 0.074 11.9 0.0 1.3 1 0 0 1 1 1 0 Hus1-like protein Sulfate_transp PF00916.15 KUM57225.1 - 1.2e-69 234.4 6.8 1.2e-69 234.4 4.7 2.2 1 1 1 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KUM57225.1 - 4.2e-31 106.4 2.9 4.2e-31 106.4 2.0 4.3 5 1 0 5 5 5 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KUM57225.1 - 1.5e-06 27.5 0.0 3.2e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain SNN_transmemb PF09049.5 KUM57225.1 - 0.027 14.1 0.9 0.027 14.1 0.6 2.6 2 0 0 2 2 2 0 Stannin transmembrane STAS_2 PF13466.1 KUM57225.1 - 0.048 13.6 0.6 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 STAS domain Filament PF00038.16 KUM57226.1 - 7e-05 22.4 5.7 7e-05 22.4 3.9 5.6 4 1 2 6 6 6 3 Intermediate filament protein DUF948 PF06103.6 KUM57226.1 - 2.9 7.8 9.1 1.4 8.8 0.7 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) TMF_TATA_bd PF12325.3 KUM57229.1 - 1.3e-43 147.6 12.4 1.3e-43 147.6 8.6 6.1 2 1 2 5 5 5 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 KUM57229.1 - 6.7e-20 70.6 17.2 6.7e-20 70.6 11.9 10.1 5 4 5 10 10 10 1 TATA element modulatory factor 1 DNA binding NPV_P10 PF05531.7 KUM57229.1 - 1.7 8.9 29.9 0.23 11.7 0.9 6.8 8 0 0 8 8 8 0 Nucleopolyhedrovirus P10 protein Arv1 PF04161.8 KUM57230.1 - 0.097 12.5 0.1 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 Arv1-like family Tic20 PF09685.5 KUM57230.1 - 0.49 10.3 0.0 0.49 10.3 0.0 3.1 2 1 0 3 3 3 0 Tic20-like protein MFS_1 PF07690.11 KUM57231.1 - 1.7e-30 105.9 38.5 1.7e-30 105.9 26.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily His_Phos_2 PF00328.17 KUM57232.1 - 4.6e-14 52.5 0.0 1.8e-13 50.5 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) V-ATPase_H_N PF03224.9 KUM57235.1 - 2.6e-78 263.2 0.0 4.3e-78 262.5 0.0 1.3 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 KUM57235.1 - 7.6e-40 135.5 0.1 3e-39 133.6 0.0 2.1 2 0 0 2 2 2 1 V-ATPase subunit H HCaRG PF07258.9 KUM57235.1 - 0.029 13.9 0.0 0.085 12.3 0.0 1.8 1 1 0 1 1 1 0 HCaRG protein Fungal_trans_2 PF11951.3 KUM57236.1 - 3.4e-58 197.0 2.6 4.1e-58 196.8 1.8 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain PI-PLC-X PF00388.14 KUM57237.1 - 4.7e-06 26.0 0.0 6.5e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Fungal_trans PF04082.13 KUM57238.1 - 2.2e-28 98.8 0.7 4.3e-28 97.9 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.20 KUM57239.1 - 2.8e-18 66.0 0.0 3.7e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM57239.1 - 7.8e-16 57.9 0.0 1e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KUM57239.1 - 0.0013 18.1 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family DUF2457 PF10446.4 KUM57239.1 - 0.002 16.9 19.5 0.0028 16.4 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) APH PF01636.18 KUM57239.1 - 0.0029 17.3 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KUM57239.1 - 0.011 14.7 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like CobT PF06213.7 KUM57239.1 - 0.04 13.0 16.1 0.056 12.5 11.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.5 KUM57239.1 - 0.8 8.7 7.8 1.1 8.2 5.4 1.1 1 0 0 1 1 1 0 BUD22 CENP-T PF15511.1 KUM57239.1 - 2.7 7.1 7.0 6.6 5.8 4.9 1.5 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T NAPRTase PF04095.11 KUM57240.1 - 3.5e-51 173.8 0.0 4.5e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family RHS_repeat PF05593.9 KUM57242.1 - 2.7e-15 56.0 49.6 6.7e-05 22.9 0.1 12.5 15 0 0 15 15 15 6 RHS Repeat DUF4112 PF13430.1 KUM57242.1 - 0.16 11.9 0.0 0.42 10.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4112) Cupin_1 PF00190.17 KUM57243.1 - 2.6e-29 101.5 0.0 1.2e-14 53.9 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 KUM57243.1 - 3.3e-24 84.1 3.4 3.2e-11 42.5 0.0 2.7 3 0 0 3 3 3 2 Cupin domain Cupin_3 PF05899.7 KUM57243.1 - 1.3e-10 40.4 0.0 1.8e-05 24.0 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 KUM57243.1 - 8.7e-07 28.7 0.1 0.00097 18.8 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.2 KUM57243.1 - 0.0028 17.3 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 2 Cupin Aa_trans PF01490.13 KUM57244.1 - 7.2e-38 130.1 35.7 8.7e-38 129.8 24.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 KUM57245.1 - 1.3e-35 122.7 35.8 1.6e-35 122.5 24.8 1.0 1 0 0 1 1 1 1 Amino acid permease MCLC PF05934.6 KUM57245.1 - 0.16 10.2 0.0 0.26 9.5 0.0 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) adh_short_C2 PF13561.1 KUM57246.1 - 4.5e-30 105.1 0.0 5.2e-30 104.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KUM57246.1 - 5.8e-29 101.1 0.2 7.2e-29 100.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM57246.1 - 1.8e-15 57.0 0.1 2.4e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 KR domain Sugar_tr PF00083.19 KUM57248.1 - 2.4e-93 313.1 27.0 2.9e-93 312.9 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM57248.1 - 4.4e-24 84.8 26.0 4.4e-24 84.8 18.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM57248.1 - 6.9e-07 27.8 1.4 1.3e-06 26.8 1.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KUM57249.1 - 2.5e-41 141.5 31.8 3.2e-41 141.2 22.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM57249.1 - 5.2e-16 58.2 13.4 5.2e-16 58.2 9.3 1.7 1 1 0 2 2 2 1 Sugar (and other) transporter DUF1049 PF06305.6 KUM57249.1 - 0.2 11.1 0.1 0.2 11.1 0.0 5.2 6 0 0 6 6 6 0 Protein of unknown function (DUF1049) zf-DHHC PF01529.15 KUM57249.1 - 3.4 7.0 4.6 0.76 9.1 0.5 1.8 2 0 0 2 2 2 0 DHHC palmitoyltransferase SRP_SPB PF02978.14 KUM57250.1 - 0.027 14.7 0.9 0.065 13.4 0.6 1.7 1 1 0 1 1 1 0 Signal peptide binding domain DUF1275 PF06912.6 KUM57251.1 - 9.7e-37 126.1 17.0 1.2e-36 125.9 11.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF4131 PF13567.1 KUM57251.1 - 5.1 6.4 15.7 4.2 6.7 5.3 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) MFS_1 PF07690.11 KUM57252.1 - 1.2e-26 93.2 33.8 1.2e-26 93.2 23.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM57252.1 - 3.4e-08 32.5 15.5 3.4e-08 32.5 10.8 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KUM57252.1 - 4e-06 25.3 2.2 6.8e-06 24.5 1.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Dioxygenase_C PF00775.16 KUM57253.1 - 1.7e-12 46.9 0.2 2.7e-12 46.3 0.2 1.3 1 0 0 1 1 1 1 Dioxygenase Lipoxygenase PF00305.14 KUM57254.1 - 5.1e-54 183.3 0.6 3.5e-53 180.6 0.4 1.9 1 1 0 1 1 1 1 Lipoxygenase PepX_C PF08530.5 KUM57256.1 - 2.9e-19 69.8 0.0 3.9e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.13 KUM57256.1 - 0.00089 18.7 0.2 0.0012 18.3 0.2 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Fungal_trans_2 PF11951.3 KUM57257.1 - 1.5e-07 30.3 0.3 1.5e-06 27.0 0.2 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain ABC_membrane PF00664.18 KUM57258.1 - 5e-79 265.5 42.2 2.8e-42 145.0 7.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KUM57258.1 - 3.2e-74 247.7 0.1 6e-36 123.7 0.0 3.0 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.14 KUM57258.1 - 3.4e-12 46.0 3.2 0.00031 20.0 0.0 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KUM57258.1 - 7.3e-12 45.8 0.1 0.027 14.4 0.0 4.3 2 2 0 3 3 3 3 AAA domain AAA_16 PF13191.1 KUM57258.1 - 2.4e-09 37.4 5.0 1.2e-05 25.3 0.1 3.2 3 1 0 3 3 2 2 AAA ATPase domain ABC_ATPase PF09818.4 KUM57258.1 - 7.5e-08 31.3 2.9 0.011 14.3 0.0 3.6 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 KUM57258.1 - 4e-07 30.8 0.0 0.066 14.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KUM57258.1 - 6.3e-07 28.7 0.1 0.079 12.1 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KUM57258.1 - 9e-07 28.3 1.3 0.021 14.3 0.4 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KUM57258.1 - 1.1e-05 25.6 1.3 0.43 10.7 0.1 4.1 3 2 0 3 3 2 2 AAA domain AAA_30 PF13604.1 KUM57258.1 - 2.4e-05 23.9 0.6 3.7 7.0 0.0 4.3 4 0 0 4 4 4 1 AAA domain AAA_14 PF13173.1 KUM57258.1 - 7.6e-05 22.6 0.0 2 8.3 0.0 3.8 4 0 0 4 4 3 2 AAA domain AAA_18 PF13238.1 KUM57258.1 - 9.1e-05 22.7 0.0 0.5 10.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KUM57258.1 - 0.00022 21.0 2.4 0.2 11.6 0.1 3.2 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 KUM57258.1 - 0.00024 20.8 0.2 1.8 8.2 0.0 3.8 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KUM57258.1 - 0.00033 20.1 4.8 0.19 11.1 0.0 3.3 4 0 0 4 4 3 2 AAA domain PRK PF00485.13 KUM57258.1 - 0.0006 19.4 0.0 0.22 11.0 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.1 KUM57258.1 - 0.00077 19.4 0.3 1.1 9.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 KUM57258.1 - 0.00088 19.1 0.2 0.11 12.3 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_10 PF12846.2 KUM57258.1 - 0.00097 18.6 0.6 2 7.8 0.0 3.9 4 0 0 4 4 4 1 AAA-like domain AAA_33 PF13671.1 KUM57258.1 - 0.0031 17.4 0.0 4.1 7.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KUM57258.1 - 0.0056 15.8 0.0 0.89 8.6 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ATP-synt_ab PF00006.20 KUM57258.1 - 0.0062 16.0 5.6 0.76 9.2 0.9 3.5 3 1 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.18 KUM57258.1 - 0.0069 16.3 0.0 1.5 8.7 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.17 KUM57258.1 - 0.0071 16.5 0.0 7.1 6.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 KUM57258.1 - 0.0082 16.3 4.9 6.1 7.0 0.3 4.3 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KUM57258.1 - 0.014 14.2 0.6 2.5 6.8 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Miro PF08477.8 KUM57258.1 - 0.029 14.8 0.0 4.4 7.8 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_24 PF13479.1 KUM57258.1 - 0.035 13.6 1.2 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Dala_Dala_lig_N PF01820.16 KUM57258.1 - 0.036 14.3 0.0 13 6.1 0.0 2.6 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus NACHT PF05729.7 KUM57258.1 - 0.041 13.5 1.5 4.2 6.9 0.1 2.6 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 KUM57258.1 - 0.044 12.8 0.1 3.1 6.8 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin APS_kinase PF01583.15 KUM57258.1 - 0.047 13.3 0.3 10 5.7 0.0 3.1 3 0 0 3 3 3 0 Adenylylsulphate kinase MobB PF03205.9 KUM57258.1 - 0.053 13.2 0.0 11 5.7 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 KUM57258.1 - 0.055 13.8 1.4 2 8.6 0.0 2.8 2 1 0 2 2 2 0 AAA domain Spectrin PF00435.16 KUM57260.1 - 0.02 15.1 0.2 0.038 14.2 0.1 1.4 1 0 0 1 1 1 0 Spectrin repeat BssS PF13991.1 KUM57260.1 - 0.083 12.6 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 BssS protein family Bac_export_3 PF01313.14 KUM57261.1 - 0.043 13.4 2.2 0.079 12.6 1.5 1.4 1 0 0 1 1 1 0 Bacterial export proteins, family 3 DUF3723 PF12520.3 KUM57262.1 - 4.7e-41 140.8 0.2 6.8e-41 140.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) Arena_nucleocap PF00843.12 KUM57262.1 - 0.13 10.1 0.1 1.6 6.4 0.0 2.0 2 0 0 2 2 2 0 Arenavirus nucleocapsid protein F-box-like PF12937.2 KUM57263.1 - 3.7e-06 26.5 0.8 3.7e-06 26.5 0.5 1.7 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 KUM57263.1 - 0.015 15.0 1.2 0.02 14.6 0.2 1.8 2 0 0 2 2 2 0 F-box-like domain SDA1 PF05285.7 KUM57263.1 - 1 8.5 13.2 1.3 8.2 9.2 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 KUM57263.1 - 3.9 5.3 10.7 4.8 5.0 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.7 KUM57263.1 - 4.4 6.3 11.8 5.6 6.0 8.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 KUM57263.1 - 7.2 4.3 13.4 8.4 4.1 9.3 1.1 1 0 0 1 1 1 0 Nop14-like family AHH PF14412.1 KUM57265.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH NAD_binding_4 PF07993.7 KUM57266.1 - 3.5e-43 147.3 0.0 5.2e-43 146.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 KUM57266.1 - 4e-11 43.0 0.0 8.9e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 KUM57266.1 - 1.2e-09 37.9 0.0 2.5e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KUM57266.1 - 4.4e-05 22.3 0.1 0.18 10.4 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KUM57266.1 - 0.058 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KUM57266.1 - 0.068 13.1 0.2 0.28 11.1 0.1 2.0 2 0 0 2 2 2 0 NADH(P)-binding RNA_pol_L_2 PF13656.1 KUM57266.1 - 0.085 12.2 0.1 1.2 8.5 0.0 2.6 3 0 0 3 3 3 0 RNA polymerase Rpb3/Rpb11 dimerisation domain adh_short PF00106.20 KUM57266.1 - 0.14 12.1 0.7 2 8.3 0.1 2.6 3 0 0 3 3 3 0 short chain dehydrogenase GMC_oxred_N PF00732.14 KUM57267.1 - 1.8e-45 155.3 0.0 2.8e-45 154.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KUM57267.1 - 1.8e-36 125.5 0.1 2.9e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase 2OG-FeII_Oxy_2 PF13532.1 KUM57268.1 - 2.1e-36 125.5 0.2 2.8e-36 125.1 0.1 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 KUM57268.1 - 0.00093 19.0 5.4 0.0018 18.1 3.7 1.5 1 0 0 1 1 1 1 GRF zinc finger CUE PF02845.11 KUM57268.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 CUE domain Asp_Glu_race PF01177.17 KUM57272.1 - 4.1e-30 105.3 0.6 4.8e-30 105.0 0.4 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase AAA_10 PF12846.2 KUM57275.1 - 2.7e-05 23.7 0.0 0.043 13.2 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain Zeta_toxin PF06414.7 KUM57275.1 - 0.05 12.6 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.13 KUM57275.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family UQ_con PF00179.21 KUM57276.1 - 2.2e-10 40.0 0.0 3.4e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KUM57276.1 - 0.14 12.0 0.1 0.33 10.8 0.0 1.6 2 0 0 2 2 2 0 RWD domain Fungal_trans PF04082.13 KUM57277.1 - 4.2e-05 22.5 0.1 8.1e-05 21.6 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DIOX_N PF14226.1 KUM57278.1 - 4.9e-32 110.8 0.1 6.9e-32 110.4 0.1 1.1 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Pectinesterase PF01095.14 KUM57279.1 - 4.5e-27 94.3 0.0 4.4e-21 74.7 0.0 2.1 2 0 0 2 2 2 2 Pectinesterase HnRNP_M PF11532.3 KUM57279.1 - 0.12 12.4 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein M F-box PF00646.28 KUM57280.1 - 5.2e-05 22.7 0.7 0.00016 21.2 0.5 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KUM57280.1 - 0.0056 16.3 0.3 0.015 15.0 0.2 1.7 1 0 0 1 1 1 1 F-box-like Sugar_tr PF00083.19 KUM57281.1 - 8.1e-126 420.2 23.0 1e-125 419.8 16.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM57281.1 - 5.1e-24 84.6 24.2 5.1e-24 84.6 16.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM57282.1 - 2.3e-44 151.7 9.5 3.1e-44 151.3 6.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM57282.1 - 1.4e-05 24.0 7.1 1.4e-05 24.0 4.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DDOST_48kD PF03345.9 KUM57282.1 - 0.025 13.1 0.0 0.036 12.6 0.0 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta DUF4383 PF14325.1 KUM57282.1 - 0.33 10.9 7.8 1.7 8.6 5.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4383) DUF3377 PF11857.3 KUM57282.1 - 0.54 9.9 2.3 1.2 8.7 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF202 PF02656.10 KUM57282.1 - 2 8.6 5.0 22 5.3 3.5 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF202) AGTRAP PF06396.6 KUM57282.1 - 2.1 8.0 6.3 10 5.7 0.2 2.2 2 0 0 2 2 2 0 Angiotensin II, type I receptor-associated protein (AGTRAP) Sugar_tr PF00083.19 KUM57283.1 - 1.9e-09 36.6 0.1 2.6e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM57283.1 - 1.9e-05 23.5 0.3 2.7e-05 23.0 0.2 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KUM57283.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 MFS_1 like family Zn_clus PF00172.13 KUM57284.1 - 3.5e-07 30.0 10.2 8.7e-07 28.7 7.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SNARE PF05739.14 KUM57285.1 - 1.3e-17 63.2 2.2 1.8e-17 62.7 0.4 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KUM57285.1 - 6.4e-15 55.1 1.7 3.5e-14 52.8 0.1 2.4 2 0 0 2 2 2 1 Syntaxin DUF4504 PF14953.1 KUM57285.1 - 0.0085 15.4 0.8 0.62 9.3 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4504) MCPsignal PF00015.16 KUM57285.1 - 0.011 15.2 0.7 0.011 15.2 0.5 2.2 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Sed5p PF11416.3 KUM57285.1 - 0.083 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Integral membrane protein Sed5p zf-C4H2 PF10146.4 KUM57285.1 - 0.12 12.4 0.5 0.91 9.4 0.0 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein NPV_P10 PF05531.7 KUM57285.1 - 0.2 11.9 2.2 65 3.8 0.0 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein MFS_1 PF07690.11 KUM57289.1 - 3.2e-15 55.6 64.4 2.4e-13 49.5 42.8 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM57289.1 - 3.5e-12 45.3 29.8 4.7e-12 44.8 20.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.7 KUM57289.1 - 0.014 15.3 1.2 0.014 15.3 0.8 2.6 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Arylsulfotran_2 PF14269.1 KUM57290.1 - 2.6e-117 391.2 5.5 3.9e-117 390.6 3.8 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) AA_permease PF00324.16 KUM57291.1 - 1.5e-131 439.0 43.5 1.7e-131 438.8 30.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KUM57291.1 - 1.2e-34 119.6 50.1 1.6e-34 119.1 34.7 1.0 1 0 0 1 1 1 1 Amino acid permease TRI5 PF06330.6 KUM57292.1 - 4.3e-15 55.2 0.4 5.2e-15 54.9 0.3 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) SVM_signal PF12113.3 KUM57292.1 - 0.09 12.6 0.4 0.19 11.5 0.3 1.6 1 0 0 1 1 1 0 SVM protein signal sequence Acetyltransf_1 PF00583.19 KUM57293.1 - 2.9e-12 46.4 0.1 5.6e-12 45.5 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KUM57293.1 - 2.4e-10 40.4 0.0 2.4e-09 37.2 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KUM57293.1 - 1.6e-06 28.2 0.2 4e-06 26.9 0.1 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KUM57293.1 - 2.3e-05 24.2 0.1 0.00034 20.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KUM57293.1 - 0.0056 16.5 0.1 0.014 15.2 0.0 1.7 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 KUM57293.1 - 0.04 13.6 0.0 0.13 11.9 0.0 1.9 1 1 0 1 1 1 0 FR47-like protein Pyr_redox PF00070.22 KUM57294.1 - 2.6e-12 46.9 0.8 5.9e-10 39.4 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KUM57294.1 - 3.7e-09 36.9 0.0 0.0005 20.1 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KUM57294.1 - 3.7e-06 26.9 1.6 0.016 15.0 0.2 3.0 3 2 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KUM57294.1 - 9.7e-06 24.7 0.0 2.9e-05 23.1 0.1 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 KUM57294.1 - 0.00027 20.0 0.0 0.00081 18.4 0.0 1.7 1 1 1 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.9 KUM57294.1 - 0.0033 16.1 0.1 1.1 7.8 0.5 2.7 3 0 0 3 3 3 2 Tryptophan halogenase DAO PF01266.19 KUM57294.1 - 0.0068 15.3 2.4 0.074 11.9 0.4 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.17 KUM57294.1 - 0.09 11.6 0.1 1.5 7.5 0.0 2.5 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KUM57294.1 - 0.1 12.3 0.1 5.7 6.6 0.0 3.2 4 0 0 4 4 4 0 FAD-NAD(P)-binding HI0933_like PF03486.9 KUM57294.1 - 0.11 10.9 0.4 0.37 9.1 0.2 2.0 3 0 0 3 3 3 0 HI0933-like protein ABC_membrane PF00664.18 KUM57295.1 - 6e-69 232.5 32.9 1.9e-41 142.2 8.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KUM57295.1 - 1.1e-66 223.3 0.0 5.2e-33 114.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KUM57295.1 - 3.4e-16 59.1 0.3 1.1e-05 24.8 0.0 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KUM57295.1 - 1.6e-09 38.1 0.0 0.025 14.5 0.0 4.3 4 0 0 4 4 4 3 AAA domain AAA_16 PF13191.1 KUM57295.1 - 4.9e-09 36.4 2.9 0.00012 22.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KUM57295.1 - 4.3e-08 32.5 0.7 0.0049 16.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KUM57295.1 - 7.4e-07 30.0 0.0 0.07 13.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 KUM57295.1 - 3.9e-06 25.7 0.3 0.0019 16.8 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_25 PF13481.1 KUM57295.1 - 6.7e-06 25.6 0.1 0.12 11.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.1 KUM57295.1 - 8e-06 25.5 1.0 0.12 11.8 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.1 KUM57295.1 - 1.8e-05 24.8 0.5 0.41 10.7 0.1 4.1 3 1 0 3 3 3 1 AAA domain DUF258 PF03193.11 KUM57295.1 - 4.7e-05 22.6 0.0 0.018 14.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 KUM57295.1 - 0.0002 21.2 0.2 1.3 9.0 0.0 3.3 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 KUM57295.1 - 0.00025 20.9 0.0 1.2 9.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain APS_kinase PF01583.15 KUM57295.1 - 0.00036 20.2 0.3 0.21 11.2 0.1 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase Zeta_toxin PF06414.7 KUM57295.1 - 0.00054 19.1 0.2 0.19 10.8 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.1 KUM57295.1 - 0.0014 18.8 0.0 2.8 8.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KUM57295.1 - 0.003 17.8 0.0 1.1 9.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KUM57295.1 - 0.0047 16.3 0.5 2.6 7.4 0.0 3.1 3 0 0 3 3 3 1 AAA-like domain DUF3987 PF13148.1 KUM57295.1 - 0.006 15.2 0.0 1.5 7.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) AAA PF00004.24 KUM57295.1 - 0.014 15.6 0.6 37 4.5 0.0 4.2 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KUM57295.1 - 0.014 15.1 0.0 4.2 7.0 0.0 3.3 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) DUF87 PF01935.12 KUM57295.1 - 0.016 15.0 0.4 2.5 7.8 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 KUM57295.1 - 0.044 13.7 0.1 9.1 6.2 0.0 3.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase NB-ARC PF00931.17 KUM57295.1 - 0.046 12.5 0.0 6.4 5.5 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain MobB PF03205.9 KUM57295.1 - 0.057 13.1 0.1 10 5.8 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Acetyltransf_8 PF13523.1 KUM57296.1 - 2.1e-39 134.8 0.5 3.3e-39 134.1 0.4 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AMP-binding PF00501.23 KUM57297.1 - 1.4e-88 297.1 0.0 3.3e-85 286.0 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KUM57297.1 - 3.4e-62 210.0 0.0 6.9e-34 117.0 0.0 2.4 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KUM57297.1 - 9.4e-26 89.8 0.7 1.7e-12 47.3 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site DUF4507 PF14964.1 KUM57298.1 - 0.034 12.8 0.0 0.038 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4507) Alpha-amylase PF00128.19 KUM57299.1 - 7.7e-54 183.2 0.0 1.2e-53 182.6 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 KUM57299.1 - 1.5e-22 79.4 0.3 3e-22 78.5 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Avirulence PF03377.8 KUM57299.1 - 0.14 10.8 0.0 0.76 8.4 0.0 1.9 2 0 0 2 2 2 0 Xanthomonas avirulence protein, Avr/PthA Alpha-amylase PF00128.19 KUM57300.1 - 2e-19 70.1 2.7 4.7e-19 68.9 0.2 2.6 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 KUM57300.1 - 2.8e-15 56.5 0.1 4.6e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 KUM57300.1 - 5.7e-08 32.9 0.0 1.7e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 KUM57300.1 - 9.2e-07 28.4 0.0 1.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 adh_short_C2 PF13561.1 KUM57301.1 - 2.4e-23 83.1 0.0 2.8e-23 82.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KUM57301.1 - 4.2e-22 78.8 0.4 5.1e-22 78.5 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM57301.1 - 1e-12 48.0 0.2 1.4e-12 47.6 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM57301.1 - 0.0024 17.3 0.3 0.0043 16.5 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GPI-anchored PF10342.4 KUM57302.1 - 2e-14 53.8 3.5 2e-14 53.8 2.4 2.6 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Macoilin PF09726.4 KUM57302.1 - 0.056 11.7 26.1 0.065 11.5 18.1 1.0 1 0 0 1 1 1 0 Transmembrane protein SOG2 PF10428.4 KUM57302.1 - 1.9 7.0 23.4 2.2 6.8 16.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF605 PF04652.11 KUM57302.1 - 2.1 7.6 17.0 2.5 7.4 11.8 1.2 1 0 0 1 1 1 0 Vta1 like FAD_binding_3 PF01494.14 KUM57303.1 - 7.6e-27 94.2 0.0 2.5e-26 92.5 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KUM57303.1 - 3.5e-05 22.8 0.5 0.023 13.6 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KUM57303.1 - 8.8e-05 22.4 0.3 0.00022 21.1 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KUM57303.1 - 0.0037 16.4 0.2 0.93 8.4 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SE PF08491.5 KUM57303.1 - 0.0053 15.6 0.0 0.48 9.1 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase B12-binding PF02310.14 KUM57303.1 - 0.018 14.9 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain FAD_binding_2 PF00890.19 KUM57303.1 - 0.029 13.2 1.5 0.048 12.4 0.6 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 KUM57303.1 - 0.035 13.9 0.1 0.061 13.2 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans_2 PF11951.3 KUM57304.1 - 6.5e-09 34.8 0.0 8e-09 34.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DEAD PF00270.24 KUM57306.1 - 1.3e-31 109.4 2.4 6.8e-31 107.0 0.1 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM57306.1 - 8.5e-22 76.8 0.1 1.6e-21 75.9 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KUM57306.1 - 0.029 14.1 0.5 0.28 10.9 0.0 2.6 2 1 1 3 3 3 0 Part of AAA domain AAA_30 PF13604.1 KUM57306.1 - 0.088 12.3 0.0 0.44 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain Fungal_trans PF04082.13 KUM57307.1 - 5.2e-10 38.6 0.2 1.2e-09 37.4 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain SH3_9 PF14604.1 KUM57309.1 - 5.1e-22 77.2 0.4 5e-11 42.0 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KUM57309.1 - 6.3e-18 63.9 1.0 1.7e-09 36.9 0.0 2.7 3 0 0 3 3 3 2 SH3 domain C1_1 PF00130.17 KUM57309.1 - 1.1e-14 53.8 5.6 1.7e-14 53.2 3.9 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_2 PF07653.12 KUM57309.1 - 0.00067 19.1 0.0 0.29 10.6 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 KUM57309.1 - 0.004 17.2 0.5 0.039 14.1 0.1 2.2 2 0 0 2 2 2 1 Bacterial SH3 domain C1_2 PF03107.11 KUM57309.1 - 0.11 12.6 7.2 0.18 11.9 5.0 1.3 1 0 0 1 1 1 0 C1 domain GTP_CH_N PF12471.3 KUM57311.1 - 1.2e-90 302.3 0.0 1.8e-90 301.8 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 KUM57311.1 - 2.9e-17 62.4 0.0 4.6e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II FSH1 PF03959.8 KUM57312.1 - 1.8e-31 109.2 0.0 3.6e-31 108.2 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KUM57312.1 - 0.00015 21.7 0.2 0.0002 21.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3632 PF12311.3 KUM57313.1 - 5.9e-22 78.3 0.6 9.5e-22 77.6 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) NAD_binding_6 PF08030.7 KUM57314.1 - 5.1e-19 68.7 0.0 1.4e-18 67.2 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KUM57314.1 - 1.8e-16 60.3 12.6 1.8e-16 60.3 8.7 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KUM57314.1 - 3.1e-13 49.5 0.0 6.2e-12 45.3 0.0 2.8 2 1 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.16 KUM57314.1 - 0.011 16.2 0.1 0.22 12.0 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF1049 PF06305.6 KUM57314.1 - 0.11 11.9 0.1 0.11 11.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF2014 PF09427.5 KUM57315.1 - 6.4e-100 333.6 0.2 9.8e-100 332.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 KUM57315.1 - 6.7e-19 67.3 0.4 1.7e-18 66.0 0.3 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain NUDE_C PF04880.8 KUM57315.1 - 0.0012 19.2 2.3 0.0012 19.2 1.6 2.6 3 0 0 3 3 3 1 NUDE protein, C-terminal conserved region Leu_zip PF15294.1 KUM57315.1 - 0.0051 15.9 1.1 0.0084 15.2 0.7 1.2 1 0 0 1 1 1 1 Leucine zipper bZIP_1 PF00170.16 KUM57315.1 - 0.065 13.1 3.5 0.047 13.6 0.6 2.1 2 0 0 2 2 2 0 bZIP transcription factor Herpes_UL6 PF01763.11 KUM57315.1 - 0.26 9.4 1.0 0.41 8.7 0.7 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like ADH_zinc_N PF00107.21 KUM57316.1 - 1.6e-12 47.0 0.0 4.6e-12 45.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM57316.1 - 5.2e-07 29.3 0.1 9.1e-06 25.4 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KUM57316.1 - 0.016 16.1 0.0 0.037 14.9 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Phosphorylase PF00343.15 KUM57317.1 - 0 1073.8 0.5 0 1073.6 0.4 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase AAA_35 PF14516.1 KUM57317.1 - 0.1 11.2 0.0 0.18 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain DUF4366 PF14283.1 KUM57318.1 - 0.0011 18.4 0.9 0.0011 18.4 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) NapE PF06796.6 KUM57318.1 - 0.011 14.9 1.2 0.018 14.3 0.9 1.3 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE CENP-B_dimeris PF09026.5 KUM57318.1 - 0.065 13.4 7.9 0.058 13.6 5.5 1.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.1 KUM57318.1 - 0.65 9.6 4.0 0.65 9.6 2.7 1.1 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.8 KUM57318.1 - 1.6 8.3 6.4 1.4 8.4 4.4 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region Cytomega_UL84 PF06284.6 KUM57318.1 - 1.7 6.9 4.1 1.8 6.9 2.9 1.0 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Rpp20 PF12328.3 KUM57318.1 - 2.7 7.6 5.0 2.7 7.6 3.4 1.1 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Prp19_bind PF06991.6 KUM57318.1 - 3.7 6.7 10.8 3.5 6.8 7.5 1.0 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain Pox_RNA_Pol_19 PF05320.7 KUM57318.1 - 4.8 6.9 5.7 4.7 6.9 4.0 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Mak16 PF04874.9 KUM57318.1 - 5.4 7.1 15.0 5.9 7.0 10.4 1.1 1 0 0 1 1 1 0 Mak16 protein C-terminal region VID27 PF08553.5 KUM57318.1 - 9.1 4.3 8.7 8.6 4.4 6.0 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Voldacs PF03517.8 KUM57318.1 - 9.5 6.0 7.3 10 5.9 5.0 1.1 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling End3 PF12761.2 KUM57319.1 - 2.8e-74 248.9 0.1 4.3e-74 248.3 0.1 1.3 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 KUM57319.1 - 2e-51 172.0 0.3 3.1e-48 161.8 0.2 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 KUM57319.1 - 6.3e-08 31.3 0.1 3.3e-07 29.1 0.2 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 KUM57319.1 - 1.9e-05 24.1 0.2 0.00039 20.0 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 KUM57319.1 - 1.9e-05 24.6 0.3 7.7e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 KUM57319.1 - 4.2e-05 23.0 0.1 9.7e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KUM57319.1 - 0.00049 19.3 0.2 0.0019 17.4 0.1 2.0 1 0 0 1 1 1 1 EF hand TPR_MLP1_2 PF07926.7 KUM57319.1 - 0.0028 17.4 1.6 0.19 11.4 0.3 2.5 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.6 KUM57319.1 - 0.073 12.5 0.5 0.073 12.5 0.3 1.8 2 0 0 2 2 2 0 Phage minor structural protein GP20 Rabaptin PF03528.10 KUM57319.1 - 0.11 12.3 4.7 1.2 9.0 3.3 2.5 1 1 0 1 1 1 0 Rabaptin DUF4407 PF14362.1 KUM57319.1 - 0.29 10.0 1.6 0.44 9.4 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IncA PF04156.9 KUM57319.1 - 2.9 7.4 6.4 19 4.8 2.3 2.6 3 0 0 3 3 3 0 IncA protein Aldo_ket_red PF00248.16 KUM57320.1 - 1.1e-38 132.7 0.0 1.3e-38 132.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.20 KUM57322.1 - 8.6e-73 244.6 0.0 1.1e-72 244.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM57322.1 - 1.9e-31 109.0 0.0 2.3e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KUM57322.1 - 3.2e-05 23.0 0.0 0.00012 21.1 0.0 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KUM57322.1 - 0.00037 19.5 0.0 0.041 12.8 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 KUM57322.1 - 0.00053 19.7 0.0 0.0018 18.0 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KUM57322.1 - 0.051 12.9 0.0 0.079 12.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family G-alpha PF00503.15 KUM57323.1 - 4.5e-33 114.4 0.0 5e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Cupin_2 PF07883.6 KUM57324.1 - 3.5e-07 29.6 0.4 6.8e-07 28.7 0.3 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 KUM57324.1 - 3.7e-07 29.6 0.0 4.3e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 KUM57324.1 - 0.001 18.6 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 Cupin ARD PF03079.9 KUM57324.1 - 0.0015 18.4 0.1 0.0024 17.8 0.0 1.4 1 1 0 1 1 1 1 ARD/ARD' family Cullin PF00888.17 KUM57325.1 - 3.7e-205 682.9 15.6 3.7e-205 682.9 10.8 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 KUM57325.1 - 1.8e-27 94.9 4.9 1.8e-27 94.9 3.4 3.2 3 0 0 3 3 3 1 Cullin protein neddylation domain WGG PF10273.4 KUM57325.1 - 0.078 13.0 6.2 19 5.4 0.0 4.4 4 0 0 4 4 4 0 Pre-rRNA-processing protein TSR2 Kinase-PPPase PF03618.9 KUM57325.1 - 1.3 8.4 9.2 5.6 6.3 0.7 2.5 2 0 0 2 2 2 0 Kinase/pyrophosphorylase Avl9 PF09794.4 KUM57326.1 - 1.7e-137 457.9 0.0 2.3e-137 457.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 KUM57326.1 - 8.4e-07 28.6 0.1 0.017 14.8 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 KUM57326.1 - 4.4e-05 22.8 2.7 0.0025 17.1 0.1 3.3 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) Mit_KHE1 PF10173.4 KUM57328.1 - 1.3e-63 214.2 0.5 2.3e-63 213.4 0.4 1.4 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related MARVEL PF01284.18 KUM57329.1 - 0.084 12.6 1.4 0.14 12.0 1.0 1.3 1 0 0 1 1 1 0 Membrane-associating domain BBE PF08031.7 KUM57330.1 - 1e-09 38.1 0.2 2.2e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 KUM57330.1 - 7.7e-09 35.1 3.8 1.1e-08 34.5 2.2 1.6 1 1 0 1 1 1 1 FAD binding domain Cytokin-bind PF09265.5 KUM57330.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding tRNA-synt_1c PF00749.16 KUM57331.1 - 2.2e-95 318.9 0.0 2.8e-95 318.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain ABC_tran PF00005.22 KUM57332.1 - 1.9e-31 109.1 0.1 3.2e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KUM57332.1 - 3.4e-08 33.8 0.1 3.4e-06 27.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 KUM57332.1 - 6.2e-08 32.1 0.9 7.3e-07 28.6 0.3 2.0 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KUM57332.1 - 0.0046 17.0 0.8 0.062 13.4 0.5 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KUM57332.1 - 0.008 16.4 0.5 0.03 14.6 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KUM57332.1 - 0.011 15.1 0.0 0.043 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KUM57332.1 - 0.011 15.1 0.1 0.029 13.8 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 KUM57332.1 - 0.025 14.4 0.2 0.085 12.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain DEAD PF00270.24 KUM57332.1 - 0.026 13.9 0.0 0.09 12.2 0.0 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase DUF87 PF01935.12 KUM57332.1 - 0.035 13.9 0.1 0.085 12.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 T2SE PF00437.15 KUM57332.1 - 0.047 12.5 0.0 0.14 11.0 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein MMR_HSR1 PF01926.18 KUM57332.1 - 0.091 12.7 0.9 0.32 10.9 0.6 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.1 KUM57332.1 - 0.12 13.2 0.1 0.3 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KUM57332.1 - 0.13 11.6 0.3 1.5 8.2 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein CbiA PF01656.18 KUM57332.1 - 0.21 10.9 1.5 2 7.7 1.1 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain 4HBT PF03061.17 KUM57333.1 - 5.8e-14 51.9 0.0 1e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 KUM57333.1 - 5.6e-07 30.0 0.0 8.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 KUM57333.1 - 0.0022 17.0 0.1 0.0035 16.3 0.1 1.3 1 0 0 1 1 1 1 Acyl-ACP thioesterase DCP2 PF05026.8 KUM57333.1 - 0.14 12.0 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 Dcp2, box A domain Hexapep PF00132.19 KUM57334.1 - 4.9e-08 32.1 10.7 0.00056 19.3 2.2 2.9 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.7 KUM57334.1 - 0.0081 14.7 5.3 0.51 8.8 0.6 2.8 1 1 1 3 3 3 2 L-fucokinase Clathrin_bdg PF15045.1 KUM57334.1 - 0.016 14.7 0.0 5.7 6.5 0.0 2.5 2 0 0 2 2 2 0 Clathrin-binding box of Aftiphilin, vesicle trafficking Hexapep_2 PF14602.1 KUM57334.1 - 3.1 7.4 14.5 3.5e+03 -2.4 10.1 3.6 1 1 0 1 1 1 0 Hexapeptide repeat of succinyl-transferase Aa_trans PF01490.13 KUM57337.1 - 4.9e-31 107.6 22.8 6.9e-31 107.1 15.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Abhydrolase_6 PF12697.2 KUM57338.1 - 3.3e-26 92.5 0.1 3.9e-26 92.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM57338.1 - 8.3e-15 54.9 0.1 1.2e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KUM57338.1 - 9.1e-14 51.4 0.0 3.7e-13 49.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KUM57338.1 - 2.1e-05 24.0 0.0 2.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.6 KUM57338.1 - 3e-05 23.2 0.0 0.0028 16.7 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) UPF0227 PF05728.7 KUM57338.1 - 0.00039 20.2 0.1 0.00071 19.3 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) Peptidase_S9 PF00326.16 KUM57338.1 - 0.00044 19.5 0.0 0.0053 15.9 0.0 2.4 3 0 0 3 3 3 1 Prolyl oligopeptidase family Thioesterase PF00975.15 KUM57338.1 - 0.0017 18.6 0.0 0.0035 17.6 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Chlorophyllase PF07224.6 KUM57338.1 - 0.018 13.8 0.1 0.054 12.2 0.1 1.7 1 1 0 1 1 1 0 Chlorophyllase Abhydrolase_2 PF02230.11 KUM57338.1 - 0.022 14.2 0.1 0.3 10.4 0.1 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF1057 PF06342.7 KUM57338.1 - 0.026 13.3 0.1 0.079 11.7 0.0 1.6 1 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) PGAP1 PF07819.8 KUM57338.1 - 0.038 13.5 0.0 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein Chlorophyllase2 PF12740.2 KUM57338.1 - 0.045 12.6 0.1 0.17 10.7 0.1 1.8 1 1 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.20 KUM57338.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) CTDII PF01556.13 KUM57339.1 - 8.9e-23 79.9 0.2 2.8e-20 71.9 0.0 2.7 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 KUM57339.1 - 1.1e-19 69.8 4.1 2.1e-19 69.0 2.9 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KUM57339.1 - 3.4e-13 49.4 21.5 5.8e-13 48.6 14.9 1.4 1 0 0 1 1 1 1 DnaJ central domain zf-CHY PF05495.7 KUM57339.1 - 0.28 11.3 10.2 1.8 8.8 1.1 2.5 1 1 1 2 2 2 0 CHY zinc finger HypA PF01155.14 KUM57339.1 - 0.32 10.6 11.0 2.1 8.0 1.5 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Sugar_tr PF00083.19 KUM57340.1 - 1.2e-114 383.4 34.2 1.4e-114 383.2 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM57340.1 - 6.5e-22 77.7 46.5 2e-19 69.5 23.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sedlin_N PF04628.8 KUM57341.1 - 4.7e-25 87.9 0.0 5.5e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF3197 PF11432.3 KUM57341.1 - 0.07 13.1 0.0 0.099 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3197) HABP4_PAI-RBP1 PF04774.10 KUM57343.1 - 0.004 17.6 4.9 0.0069 16.8 3.4 1.6 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family Ribosomal_S3Ae PF01015.13 KUM57344.1 - 1.2e-80 269.4 6.1 1.5e-80 269.1 4.2 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Acyl_transf_1 PF00698.16 KUM57345.1 - 1e-21 77.6 0.0 1.9e-13 50.4 0.0 2.1 2 0 0 2 2 2 2 Acyl transferase domain UPRTase PF14681.1 KUM57346.1 - 1.5e-78 262.7 0.0 1.9e-78 262.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KUM57346.1 - 0.0054 16.4 0.0 0.0089 15.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 KUM57346.1 - 0.09 12.5 0.3 0.14 11.9 0.2 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Ras PF00071.17 KUM57347.1 - 2e-45 154.0 0.1 2.3e-45 153.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KUM57347.1 - 1.3e-15 57.8 0.1 1.9e-15 57.4 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KUM57347.1 - 2.1e-08 33.6 0.0 2.3e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KUM57347.1 - 1.1e-06 28.5 0.0 1.4e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KUM57347.1 - 1.1e-05 24.9 0.6 0.00044 19.7 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KUM57347.1 - 0.00028 20.1 0.0 0.00037 19.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 KUM57347.1 - 0.0051 16.7 0.0 0.011 15.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KUM57347.1 - 0.014 15.2 0.0 0.023 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 KUM57347.1 - 0.03 13.6 0.0 0.22 10.7 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B WAPL PF07814.8 KUM57348.1 - 2.1e-42 145.1 0.0 3.4e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Elf1 PF05129.8 KUM57349.1 - 4.1e-29 100.0 0.2 5.4e-29 99.7 0.1 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Cript PF10235.4 KUM57349.1 - 0.098 13.0 0.7 0.19 12.0 0.2 1.8 2 1 0 2 2 2 0 Microtubule-associated protein CRIPT zf-Sec23_Sec24 PF04810.10 KUM57349.1 - 0.15 11.6 0.9 1.2 8.7 0.1 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-C2H2_6 PF13912.1 KUM57349.1 - 0.25 11.2 0.3 0.25 11.2 0.2 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger Oxidored_q6 PF01058.17 KUM57350.1 - 1.1e-22 80.0 0.0 1.9e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit tRNA-synt_2b PF00587.20 KUM57351.1 - 5.8e-32 110.6 0.0 8.9e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KUM57351.1 - 2.8e-18 65.9 5.6 2.8e-18 65.9 3.9 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Cytochrom_C552 PF02335.10 KUM57351.1 - 0.34 9.5 9.1 0.28 9.8 0.2 2.2 2 0 0 2 2 2 0 Cytochrome c552 Mnd1 PF03962.10 KUM57351.1 - 0.83 9.2 10.5 0.08 12.5 3.8 1.8 2 0 0 2 2 2 0 Mnd1 family DUF4375 PF14300.1 KUM57351.1 - 1.8 8.5 5.9 0.4 10.6 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4375) Nucleoporin_C PF03177.9 KUM57352.1 - 1.5e-110 370.5 0.0 2.5e-110 369.7 0.0 1.3 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KUM57352.1 - 5.2e-68 229.7 0.0 6.9e-68 229.3 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Glyco_hydro_43 PF04616.9 KUM57354.1 - 7.5e-40 136.8 0.4 1e-39 136.3 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 PX PF00787.19 KUM57355.1 - 2.8e-17 62.5 0.0 1.5e-16 60.2 0.0 2.2 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 KUM57355.1 - 3.6e-09 36.2 8.7 3.3e-05 23.2 0.9 2.1 2 0 0 2 2 2 2 Vps5 C terminal like Noggin PF05806.7 KUM57355.1 - 0.089 12.0 0.0 0.47 9.7 0.1 1.9 2 0 0 2 2 2 0 Noggin Peptidase_C10 PF01640.12 KUM57355.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Peptidase C10 family DUF2428 PF10350.4 KUM57356.1 - 8.1e-76 254.4 0.0 1.6e-75 253.4 0.0 1.5 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 KUM57356.1 - 5.6e-07 29.1 4.0 3.1 8.1 0.2 6.5 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 KUM57356.1 - 0.037 14.3 6.6 6.7 7.0 0.3 4.5 4 0 0 4 4 4 0 HEAT repeats HEAT_EZ PF13513.1 KUM57356.1 - 2.9 8.5 8.9 8 7.0 0.2 4.8 4 0 0 4 4 4 0 HEAT-like repeat Tim17 PF02466.14 KUM57357.1 - 1.2e-26 93.2 6.2 1.4e-26 93.0 4.3 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Fungal_trans_2 PF11951.3 KUM57358.1 - 5.7e-33 114.0 5.9 7.4e-33 113.6 4.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM57358.1 - 1.7e-11 43.8 7.4 3.1e-11 42.9 5.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclase PF04199.8 KUM57359.1 - 2.4e-09 37.1 0.0 3.6e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Pkinase PF00069.20 KUM57360.1 - 1.8e-46 158.3 0.0 4.7e-45 153.7 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM57360.1 - 8.6e-26 90.5 0.0 1.4e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM57360.1 - 0.00025 20.0 0.0 0.00055 18.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like IncA PF04156.9 KUM57361.1 - 2.3 7.7 8.3 4.9 6.7 5.7 1.5 1 0 0 1 1 1 0 IncA protein Pkinase PF00069.20 KUM57362.1 - 9.8e-10 38.0 0.0 0.00027 20.1 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Brix PF04427.13 KUM57363.1 - 1.1e-28 100.2 0.0 2.2e-28 99.2 0.0 1.5 2 0 0 2 2 2 1 Brix domain zf-rbx1 PF12678.2 KUM57364.1 - 1.5e-11 44.2 0.6 3.1e-11 43.2 0.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KUM57364.1 - 9.8e-10 38.1 3.3 9.8e-10 38.1 2.3 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KUM57364.1 - 3.3e-07 29.8 0.4 7.7e-07 28.6 0.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KUM57364.1 - 2.7e-06 26.9 5.1 1.9e-05 24.2 1.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KUM57364.1 - 1.6e-05 24.8 2.1 1.6e-05 24.8 1.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KUM57364.1 - 2.1e-05 24.1 1.8 9.4e-05 22.0 0.3 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 KUM57364.1 - 0.004 16.9 2.4 0.054 13.3 0.7 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Kinesin-relat_1 PF12711.2 KUM57364.1 - 0.0083 16.4 0.9 0.022 15.1 0.6 1.7 1 0 0 1 1 1 1 Kinesin motor CopD PF05425.8 KUM57364.1 - 0.014 15.6 1.6 0.014 15.6 1.1 2.3 1 1 1 2 2 2 0 Copper resistance protein D zf-C3HC4_4 PF15227.1 KUM57364.1 - 0.026 14.3 1.3 0.052 13.4 0.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Transposase_28 PF04195.7 KUM57364.1 - 0.075 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative gypsy type transposon zf-RING_UBOX PF13445.1 KUM57364.1 - 0.19 11.4 11.2 0.21 11.3 6.0 2.3 2 1 0 2 2 2 0 RING-type zinc-finger FlgM PF04316.8 KUM57364.1 - 1 9.3 13.3 0.32 10.9 0.8 3.0 2 1 1 3 3 3 0 Anti-sigma-28 factor, FlgM zf-RING_4 PF14570.1 KUM57364.1 - 3 7.5 5.1 0.63 9.6 1.2 1.6 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain Tim17 PF02466.14 KUM57365.1 - 3.2e-23 82.1 0.7 6.2e-23 81.2 0.5 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family EB1_binding PF05937.6 KUM57366.1 - 0.0041 17.5 12.9 0.0091 16.3 9.0 1.6 1 0 0 1 1 1 1 EB-1 Binding Domain KAR9 PF08580.5 KUM57366.1 - 0.72 8.0 13.4 0.94 7.6 9.3 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 MFS_1 PF07690.11 KUM57367.1 - 3.7e-12 45.6 3.6 3.7e-12 45.6 2.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 KUM57367.1 - 8.6e-08 31.0 0.2 0.0033 15.9 0.0 2.3 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_2 PF13347.1 KUM57367.1 - 8.9e-05 21.0 3.7 8.9e-05 21.0 2.6 2.4 2 1 0 2 2 2 1 MFS/sugar transport protein Nucleoside_tran PF01733.13 KUM57367.1 - 0.0091 15.1 0.0 0.0091 15.1 0.0 1.8 3 0 0 3 3 3 1 Nucleoside transporter DUF2569 PF10754.4 KUM57367.1 - 0.049 13.8 0.3 0.25 11.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) MFS_1_like PF12832.2 KUM57367.1 - 0.058 13.1 0.4 0.81 9.5 0.1 2.6 2 0 0 2 2 2 0 MFS_1 like family Otopetrin PF03189.8 KUM57367.1 - 0.19 10.6 1.0 14 4.4 0.3 2.4 2 1 1 3 3 3 0 Otopetrin DUF485 PF04341.7 KUM57367.1 - 0.57 9.9 3.5 0.25 11.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF485 ATP_synt_I PF03899.10 KUM57367.1 - 3.5 7.8 12.5 0.096 12.8 0.4 3.1 3 0 0 3 3 3 0 ATP synthase I chain ADH_N PF08240.7 KUM57369.1 - 2.4e-17 62.6 4.1 3.9e-17 61.9 2.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.14 KUM57369.1 - 6.4e-06 25.4 0.0 1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 KUM57369.1 - 1.3e-05 24.7 0.0 2.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KUM57369.1 - 0.0013 18.3 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 KUM57369.1 - 0.012 15.6 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 KUM57369.1 - 0.08 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 KUM57369.1 - 0.14 11.7 0.4 0.22 11.1 0.2 1.4 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 KUM57369.1 - 0.16 11.7 0.3 0.32 10.8 0.2 1.4 1 0 0 1 1 1 0 ThiF family adh_short PF00106.20 KUM57370.1 - 3.2e-20 72.7 0.5 4.6e-20 72.1 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM57370.1 - 1.4e-09 37.8 0.3 1.7e-09 37.5 0.2 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KUM57370.1 - 6.1e-07 29.4 1.0 7.6e-07 29.1 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KUM57370.1 - 6.6e-05 22.4 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KUM57370.1 - 0.00019 21.4 0.7 0.00024 21.1 0.5 1.5 1 1 0 1 1 1 1 NADH(P)-binding DUF4584 PF15223.1 KUM57371.1 - 0.026 13.8 1.6 0.027 13.7 1.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4584) TFIIF_alpha PF05793.7 KUM57371.1 - 0.041 12.2 5.5 0.049 12.0 3.8 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1365 PF07103.6 KUM57372.1 - 1.2e-12 47.4 0.1 9.4e-10 37.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1365) DUF3431 PF11913.3 KUM57373.1 - 1.9e-87 292.3 0.0 2.5e-87 292.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Prenyltrans_1 PF13243.1 KUM57375.1 - 1.2e-09 38.1 0.0 6.2e-05 22.9 0.0 2.1 1 1 1 2 2 2 2 Prenyltransferase-like Prenyltrans PF00432.16 KUM57375.1 - 2.7e-09 36.4 1.0 1e-08 34.5 0.3 2.2 2 1 0 2 2 2 1 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KUM57375.1 - 8.6e-09 35.7 0.0 1.6e-08 34.9 0.0 1.4 1 1 0 1 1 1 1 Prenyltransferase-like Pec_lyase PF09492.5 KUM57375.1 - 0.00013 21.2 0.0 0.011 14.8 0.0 2.0 1 1 0 2 2 2 2 Pectic acid lyase A2M_comp PF07678.9 KUM57375.1 - 0.0011 18.2 0.0 0.0062 15.8 0.0 1.7 1 1 1 2 2 2 1 A-macroglobulin complement component MFS_1 PF07690.11 KUM57376.1 - 3.6e-24 85.1 43.2 3.6e-24 85.1 29.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BAF1_ABF1 PF04684.8 KUM57377.1 - 0.23 10.2 13.0 0.31 9.8 9.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PAT1 PF09770.4 KUM57377.1 - 3 5.9 7.9 3.5 5.7 5.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Fungal_trans PF04082.13 KUM57378.1 - 6.1e-19 67.9 0.0 2.4e-18 65.9 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM57378.1 - 1.8e-07 30.9 13.1 2.9e-07 30.2 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_I PF01487.10 KUM57379.1 - 1.9e-48 165.0 0.0 2.6e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 KUM57379.1 - 6.9e-19 68.2 0.5 2.7e-18 66.3 0.0 2.2 3 0 0 3 3 3 1 Shikimate kinase Shikimate_DH PF01488.15 KUM57379.1 - 5.9e-14 52.3 0.0 1.3e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Shikimate_dh_N PF08501.6 KUM57379.1 - 3.3e-13 49.4 0.0 8e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain F420_oxidored PF03807.12 KUM57379.1 - 0.0049 17.2 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 KUM57379.1 - 0.052 13.3 0.1 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 ThiF family MFS_1 PF07690.11 KUM57380.1 - 9.4e-17 60.7 58.0 6.4e-09 34.9 18.7 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 KUM57380.1 - 1.1e-05 23.8 15.2 1.1e-05 23.8 10.6 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Methyltransf_2 PF00891.13 KUM57381.1 - 1.2e-16 60.6 0.0 2.6e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 KUM57381.1 - 0.00046 19.9 0.0 0.001 18.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Dimerisation PF08100.6 KUM57381.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain Fringe PF02434.11 KUM57383.1 - 1.7e-05 24.1 0.9 0.00086 18.5 0.1 2.9 2 1 0 2 2 2 1 Fringe-like PAN_1 PF00024.21 KUM57383.1 - 8.5e-05 22.2 0.2 0.00018 21.2 0.1 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 KUM57383.1 - 0.01 15.4 0.3 0.027 14.1 0.2 1.7 1 0 0 1 1 1 0 PAN domain CarbpepA_inh PF02977.10 KUM57383.1 - 0.1 12.2 0.6 0.23 11.0 0.4 1.5 1 0 0 1 1 1 0 Carboxypeptidase A inhibitor Galactosyl_T PF01762.16 KUM57383.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Galactosyltransferase Glyco_transf_34 PF05637.7 KUM57383.1 - 0.67 9.4 2.8 1.2 8.6 1.9 1.3 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family Prenyltrans PF00432.16 KUM57384.1 - 3.9e-08 32.7 0.0 8.3e-08 31.6 0.0 1.6 1 0 0 1 1 1 1 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KUM57384.1 - 4.3e-07 30.3 0.2 0.0034 17.7 0.1 2.8 2 1 0 2 2 2 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 KUM57384.1 - 0.0018 18.2 0.0 6.4 6.8 0.0 3.2 3 0 0 3 3 3 2 Prenyltransferase-like Chromadorea_ALT PF05535.7 KUM57384.1 - 0.045 13.8 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Chromadorea ALT protein DUF2235 PF09994.4 KUM57385.1 - 3.2e-88 295.6 0.0 4e-88 295.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Methyltransf_11 PF08241.7 KUM57386.1 - 1.8e-12 47.5 0.0 2.7e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM57386.1 - 2.6e-10 40.8 0.0 4.7e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM57386.1 - 1.8e-09 37.3 0.0 2.6e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM57386.1 - 1.3e-08 35.0 0.0 2.4e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM57386.1 - 1.2e-07 32.1 0.0 1.8e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM57386.1 - 8.1e-07 28.9 0.0 1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KUM57386.1 - 9.2e-05 22.4 0.1 0.00023 21.1 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KUM57386.1 - 0.00011 21.4 0.0 0.00018 20.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 KUM57386.1 - 0.00028 20.1 0.5 0.00043 19.4 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 KUM57386.1 - 0.001 18.4 0.1 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 KUM57386.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW N6_N4_Mtase PF01555.13 KUM57386.1 - 0.029 13.8 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 DNA methylase Methyltransf_16 PF10294.4 KUM57386.1 - 0.054 12.9 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase MFS_1 PF07690.11 KUM57387.1 - 1.6e-35 122.5 54.7 4.4e-35 121.0 37.9 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM57387.1 - 3.3e-13 48.7 27.0 6.5e-13 47.7 18.7 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KUM57387.1 - 8.2e-12 44.4 12.5 8.2e-12 44.4 8.6 3.5 2 1 1 3 3 3 1 Sugar (and other) transporter Pox_A14 PF05767.7 KUM57387.1 - 0.084 12.8 0.1 0.084 12.8 0.1 3.2 4 1 1 5 5 5 0 Poxvirus virion envelope protein A14 Asparaginase_II PF06089.7 KUM57388.1 - 4.1e-109 364.1 0.4 4.7e-109 363.9 0.3 1.0 1 0 0 1 1 1 1 L-asparaginase II Glyco_hydro_3 PF00933.16 KUM57389.1 - 3.1e-75 252.9 0.0 4.8e-75 252.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KUM57389.1 - 5.7e-63 212.4 0.0 8.6e-63 211.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KUM57389.1 - 3.1e-25 87.9 0.0 6.8e-25 86.8 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KUM57389.1 - 1.2e-15 57.4 0.0 2.5e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 PA14 domain T6SS-SciN PF12790.2 KUM57389.1 - 0.16 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Type VI secretion lipoprotein DUF4243 PF14027.1 KUM57390.1 - 5e-11 42.6 0.2 7.4e-11 42.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) ADH_N PF08240.7 KUM57391.1 - 5.9e-20 71.0 2.2 3.1e-18 65.5 1.5 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Sugar_tr PF00083.19 KUM57394.1 - 2.4e-73 247.2 23.8 2.8e-73 247.0 16.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM57394.1 - 1.8e-21 76.2 19.2 1.8e-21 76.2 13.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Response_reg PF00072.19 KUM57395.1 - 2.7e-18 66.0 0.1 6.5e-18 64.7 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 KUM57395.1 - 3e-17 62.3 0.0 5.9e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KUM57395.1 - 1.4e-10 41.0 0.8 6e-10 38.9 0.0 2.5 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 KUM57395.1 - 1.5e-05 25.0 0.0 0.13 12.3 0.0 3.0 3 1 0 3 3 3 2 GAF domain GAF PF01590.21 KUM57395.1 - 0.0098 16.0 0.0 0.18 11.9 0.0 2.9 3 0 0 3 3 3 1 GAF domain Git3 PF11710.3 KUM57396.1 - 2.3e-18 66.5 19.9 4.1e-18 65.6 13.8 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 KUM57396.1 - 1.1e-08 34.7 0.0 1.1e-08 34.7 0.0 2.7 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term MtrF PF09472.5 KUM57396.1 - 5.8 6.2 6.2 1.5 8.1 1.2 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Ank_2 PF12796.2 KUM57397.1 - 2.9e-80 264.7 17.0 5.4e-10 39.4 0.0 14.9 5 4 6 11 11 11 10 Ankyrin repeats (3 copies) Ank PF00023.25 KUM57397.1 - 1.4e-54 179.2 34.9 1.9e-11 43.1 0.0 21.8 22 2 0 22 22 22 12 Ankyrin repeat Ank_4 PF13637.1 KUM57397.1 - 1.9e-54 181.0 28.7 3e-07 30.7 0.1 20.2 16 5 7 23 23 23 13 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM57397.1 - 1e-46 155.8 34.9 4.7e-09 36.1 0.1 17.9 15 4 3 19 19 19 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM57397.1 - 2.4e-40 132.5 25.0 1.1e-07 31.3 0.0 20.5 22 2 1 23 23 23 9 Ankyrin repeat DUF3292 PF11696.3 KUM57398.1 - 4.5e-259 860.7 0.1 5.3e-259 860.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) FA_desaturase PF00487.19 KUM57398.1 - 1.4 8.2 3.7 0.3 10.4 0.1 1.6 2 0 0 2 2 2 0 Fatty acid desaturase DUF3640 PF12342.3 KUM57399.1 - 0.34 10.4 0.3 0.34 10.4 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3640) EBP PF05241.7 KUM57400.1 - 1.4e-67 226.5 5.9 1.7e-67 226.2 4.1 1.0 1 0 0 1 1 1 1 Emopamil binding protein Mito_carr PF00153.22 KUM57403.1 - 2e-43 146.0 0.8 3e-15 55.6 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF883 PF05957.8 KUM57403.1 - 0.66 10.4 0.1 0.66 10.4 0.1 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) MFS_1 PF07690.11 KUM57405.1 - 4.1e-37 127.7 26.8 7.2e-37 126.9 12.1 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KUM57405.1 - 2.6e-05 22.8 16.1 0.00055 18.4 3.1 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein OATP PF03137.15 KUM57405.1 - 0.0002 19.5 0.2 0.085 10.8 0.0 2.2 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF3784 PF12650.2 KUM57405.1 - 0.044 13.7 1.8 0.14 12.0 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) Zn_clus PF00172.13 KUM57407.1 - 6.9e-06 25.8 7.2 6.9e-06 25.8 5.0 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KUM57407.1 - 0.012 14.2 0.0 0.019 13.5 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF3637 PF12337.3 KUM57407.1 - 0.063 13.2 0.2 0.16 11.9 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3637) Pox_F17 PF04767.7 KUM57407.1 - 0.91 9.8 4.4 2 8.7 3.0 1.7 1 0 0 1 1 1 0 DNA-binding 11 kDa phosphoprotein MspA PF09203.6 KUM57408.1 - 0.56 9.6 4.7 0.8 9.1 0.3 2.8 2 1 1 3 3 3 0 MspA Abhydrolase_4 PF08386.5 KUM57409.1 - 1e-15 57.4 0.0 5e-15 55.2 0.0 2.0 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 KUM57409.1 - 4.2e-11 42.8 0.0 1.5e-07 31.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KUM57409.1 - 6.3e-07 29.5 0.0 5.2e-06 26.4 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family AMP-binding PF00501.23 KUM57410.1 - 0 1194.7 0.2 3.7e-78 262.7 0.0 5.2 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.15 KUM57410.1 - 5.6e-162 537.6 0.0 3.4e-32 111.5 0.0 5.5 5 0 0 5 5 5 5 Condensation domain PP-binding PF00550.20 KUM57410.1 - 1.9e-47 159.3 5.5 1.4e-09 38.0 0.0 6.0 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KUM57410.1 - 1e-19 71.2 0.3 2.4e-05 25.1 0.0 5.9 5 0 0 5 5 5 5 AMP-binding enzyme C-terminal domain GH3 PF03321.8 KUM57410.1 - 0.00012 20.7 0.0 0.23 9.9 0.0 4.4 4 0 0 4 4 4 1 GH3 auxin-responsive promoter Pilus_CpaD PF09476.5 KUM57410.1 - 0.083 12.3 0.1 34 3.8 0.0 3.3 3 0 0 3 3 3 0 Pilus biogenesis CpaD protein (pilus_cpaD) Transferase PF02458.10 KUM57410.1 - 0.39 9.1 0.5 3.3 6.0 0.0 2.7 4 0 0 4 4 4 0 Transferase family DUF4367 PF14285.1 KUM57410.1 - 4.6 6.5 0.0 8.5 5.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) DIOX_N PF14226.1 KUM57411.1 - 1.1e-20 74.3 0.0 1.9e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KUM57411.1 - 1.4e-13 50.9 0.0 2.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rootletin PF15035.1 KUM57412.1 - 0.022 14.7 1.1 0.55 10.1 0.0 2.5 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Myb_DNA-bind_5 PF13873.1 KUM57413.1 - 0.025 14.4 1.1 0.56 10.1 0.1 2.7 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KUM57413.1 - 0.11 12.6 0.5 0.22 11.6 0.3 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain FlaC_arch PF05377.6 KUM57414.1 - 0.012 15.5 0.5 0.49 10.3 0.0 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF3972 PF13118.1 KUM57414.1 - 0.061 13.3 1.1 0.24 11.4 0.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3972) Cluap1 PF10234.4 KUM57414.1 - 0.09 11.9 0.4 0.12 11.6 0.3 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Ssu72 PF04722.8 KUM57414.1 - 0.098 11.9 0.1 0.18 11.1 0.1 1.3 1 1 0 1 1 1 0 Ssu72-like protein DivIC PF04977.10 KUM57414.1 - 0.18 11.3 0.7 0.37 10.3 0.1 1.7 1 1 0 1 1 1 0 Septum formation initiator Pyr_redox_3 PF13738.1 KUM57415.1 - 1.5e-25 90.4 0.0 2.8e-24 86.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KUM57415.1 - 6.8e-13 47.6 0.0 2.7e-10 39.0 0.0 2.9 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KUM57415.1 - 5.3e-09 35.9 0.0 1.9e-08 34.1 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KUM57415.1 - 2.8e-08 33.0 0.0 0.00019 20.4 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KUM57415.1 - 1.4e-07 31.5 0.0 1.7e-05 24.7 0.0 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM57415.1 - 3.7e-06 26.8 0.7 0.00013 21.7 0.0 3.4 4 1 0 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.19 KUM57415.1 - 0.00022 20.2 0.0 0.0038 16.1 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KUM57415.1 - 0.00044 20.5 0.0 1.4 9.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase CPSase_L_chain PF00289.17 KUM57415.1 - 0.15 12.2 0.0 0.55 10.3 0.0 1.9 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain TPR_12 PF13424.1 KUM57416.1 - 7.2e-29 99.5 6.3 4.4e-17 61.7 0.2 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 KUM57416.1 - 6.5e-22 76.7 5.6 1.7e-10 40.4 0.1 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KUM57416.1 - 1.1e-11 44.2 0.3 3.5e-09 36.1 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 KUM57416.1 - 2.2e-08 33.3 3.5 0.0093 15.5 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 KUM57416.1 - 3.1e-08 32.7 5.7 0.011 15.4 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KUM57416.1 - 8.7e-07 28.4 4.7 0.035 14.0 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KUM57416.1 - 3.6e-06 27.4 5.1 1.2e-05 25.8 0.3 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KUM57416.1 - 4.4e-06 26.8 2.1 0.71 10.6 0.2 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat NB-ARC PF00931.17 KUM57416.1 - 9.3e-06 24.6 0.0 1.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Apc3 PF12895.2 KUM57416.1 - 5.1e-05 23.3 0.1 0.001 19.1 0.0 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF676 PF05057.9 KUM57416.1 - 0.00011 21.5 0.1 0.00042 19.6 0.0 1.8 1 1 1 2 2 2 1 Putative serine esterase (DUF676) TPR_4 PF07721.9 KUM57416.1 - 0.0023 18.1 0.0 2.1 9.0 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_22 PF13401.1 KUM57416.1 - 0.0042 17.2 0.0 0.015 15.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain Abhydrolase_6 PF12697.2 KUM57416.1 - 0.0052 16.6 0.0 0.013 15.4 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family TPR_19 PF14559.1 KUM57416.1 - 0.013 15.8 0.4 0.17 12.2 0.1 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat NACHT PF05729.7 KUM57416.1 - 0.016 14.8 0.0 0.036 13.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain PGAP1 PF07819.8 KUM57416.1 - 0.02 14.4 0.0 0.25 10.9 0.0 2.5 3 0 0 3 3 3 0 PGAP1-like protein TPR_17 PF13431.1 KUM57416.1 - 0.029 14.5 0.0 12 6.3 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-RVT PF13966.1 KUM57417.1 - 0.079 13.2 0.2 0.15 12.4 0.1 1.5 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase RNase_H PF00075.19 KUM57417.1 - 0.12 12.7 0.1 0.24 11.7 0.1 1.5 1 0 0 1 1 1 0 RNase H DUF3435 PF11917.3 KUM57419.1 - 9.4e-23 80.5 0.0 1.5e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Phage_integrase PF00589.17 KUM57419.1 - 0.051 13.2 0.0 0.2 11.3 0.0 1.9 2 0 0 2 2 2 0 Phage integrase family DUF515 PF04415.7 KUM57419.1 - 0.14 10.3 0.1 0.22 9.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) BTB PF00651.26 KUM57421.1 - 2.8e-13 49.8 0.1 3.5e-12 46.3 0.1 2.5 3 0 0 3 3 3 1 BTB/POZ domain Zn-ribbon_8 PF09723.5 KUM57421.1 - 0.56 10.2 3.4 0.63 10.0 0.8 2.3 2 0 0 2 2 2 0 Zinc ribbon domain C1_1 PF00130.17 KUM57421.1 - 0.78 9.5 5.6 0.11 12.2 0.5 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Nudix_N_2 PF14803.1 KUM57421.1 - 1.3 8.7 4.9 44 3.8 0.0 3.2 2 2 0 2 2 2 0 Nudix N-terminal DUF2296 PF10058.4 KUM57421.1 - 2.6 7.8 5.1 2.7 7.7 1.8 2.4 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) HTH_32 PF13565.1 KUM57423.1 - 1.3e-06 29.1 0.0 1.1e-05 26.1 0.0 2.2 1 1 1 2 2 2 1 Homeodomain-like domain DDE_3 PF13358.1 KUM57423.1 - 0.0002 21.1 0.0 0.00098 18.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 KUM57423.1 - 0.00024 21.2 0.0 0.00062 19.8 0.0 1.7 2 0 0 2 2 2 1 Winged helix-turn helix HTH_33 PF13592.1 KUM57423.1 - 0.0031 17.0 0.0 0.0075 15.7 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix Dynamin_N PF00350.18 KUM57424.1 - 2.4e-34 118.5 0.0 5.6e-34 117.3 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KUM57424.1 - 1.2e-12 47.2 0.0 5e-12 45.1 0.0 1.9 1 1 1 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 KUM57424.1 - 0.00014 21.7 0.0 0.0011 18.9 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KUM57424.1 - 0.001 19.5 0.0 0.0033 17.9 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_21 PF13304.1 KUM57424.1 - 0.041 13.8 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KUM57424.1 - 0.056 12.9 0.4 0.32 10.5 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AHH PF14412.1 KUM57424.1 - 0.13 12.3 0.1 0.33 10.9 0.1 1.6 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH GED PF02212.13 KUM57424.1 - 0.32 10.9 1.8 25 4.8 0.1 3.5 4 1 0 4 4 4 0 Dynamin GTPase effector domain Beta-lactamase PF00144.19 KUM57425.1 - 4.1e-37 127.9 0.0 7.3e-37 127.1 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 KUM57425.1 - 1e-07 31.7 0.0 2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) SnoaL_4 PF13577.1 KUM57426.1 - 1.9e-18 66.5 0.0 2.7e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Ham1p_like PF01725.11 KUM57426.1 - 0.15 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Ham1 family Amidohydro_1 PF01979.15 KUM57428.1 - 6e-23 82.0 0.1 8.2e-23 81.5 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KUM57428.1 - 4.5e-17 61.6 0.3 1.3e-16 60.1 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 KUM57428.1 - 9.8e-11 42.1 1.1 1.2e-09 38.6 0.8 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KUM57428.1 - 3.1e-06 26.6 5.1 0.012 14.8 0.0 3.2 3 0 0 3 3 3 3 Amidohydrolase family Aldose_epim PF01263.15 KUM57429.1 - 4.4e-49 167.1 0.4 5.8e-49 166.8 0.3 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Cupin_2 PF07883.6 KUM57429.1 - 0.017 14.6 0.1 0.057 12.9 0.0 1.9 2 0 0 2 2 2 0 Cupin domain FA_desaturase PF00487.19 KUM57430.1 - 7.8e-18 64.8 19.0 1.3e-17 64.0 13.2 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KUM57430.1 - 1.6e-15 56.6 0.0 3.2e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AMP-binding PF00501.23 KUM57431.1 - 1.1e-56 192.0 0.0 1.4e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KUM57431.1 - 2e-11 44.6 0.1 6e-11 43.1 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACOX PF01756.14 KUM57432.1 - 1.6e-37 128.6 0.3 4.3e-37 127.3 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 KUM57432.1 - 1.9e-25 89.5 1.3 3.6e-25 88.6 0.9 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 KUM57432.1 - 5.4e-08 32.2 0.0 1.4e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 KUM57432.1 - 0.001 19.2 0.2 0.0043 17.1 0.1 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Fungal_trans PF04082.13 KUM57433.1 - 1.8e-18 66.3 0.0 2.8e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ECH PF00378.15 KUM57434.1 - 6.4e-25 87.6 0.0 7.4e-25 87.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family GIY-YIG PF01541.19 KUM57435.1 - 0.019 15.3 0.0 0.052 13.9 0.0 1.7 1 0 0 1 1 1 0 GIY-YIG catalytic domain Glyco_hydro_16 PF00722.16 KUM57437.1 - 5.3e-12 45.3 0.2 2.8e-11 43.0 0.2 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1388 PF07142.7 KUM57438.1 - 0.01 15.5 1.1 0.01 15.5 0.8 1.9 2 0 0 2 2 2 0 Repeat of unknown function (DUF1388) EMP24_GP25L PF01105.19 KUM57439.1 - 5.2e-52 176.2 1.2 6.1e-52 175.9 0.8 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Myb_DNA-bind_6 PF13921.1 KUM57440.1 - 0.0032 17.5 0.1 0.03 14.4 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KUM57440.1 - 0.0047 16.9 0.0 0.078 13.0 0.0 2.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain Ribosomal_60s PF00428.14 KUM57440.1 - 3.3 8.1 10.6 4.1 7.8 1.0 3.8 4 0 0 4 4 4 0 60s Acidic ribosomal protein HATPase_c PF02518.21 KUM57442.1 - 6.3e-21 74.1 0.0 4.6e-20 71.3 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KUM57442.1 - 5.2e-15 55.4 0.3 0.00049 20.0 0.0 3.5 3 0 0 3 3 3 3 Response regulator receiver domain HisKA PF00512.20 KUM57442.1 - 2.1e-05 24.4 0.2 0.00033 20.6 0.0 2.8 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 KUM57442.1 - 0.057 13.0 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 KUM57442.1 - 0.077 12.7 0.0 0.49 10.1 0.0 2.3 2 1 0 2 2 2 0 Histidine kinase-like ATPase domain TUG-UBL1 PF11470.3 KUM57443.1 - 1.7e-25 88.7 0.1 3.3e-25 87.7 0.1 1.5 1 0 0 1 1 1 1 GLUT4 regulating protein TUG UBX PF00789.15 KUM57443.1 - 0.00017 21.5 0.0 0.00097 19.1 0.0 2.2 2 0 0 2 2 2 1 UBX domain EHN PF06441.7 KUM57444.1 - 6.9e-15 54.9 3.8 3e-14 52.8 0.3 2.4 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.15 KUM57444.1 - 0.00064 19.3 0.0 0.007 15.9 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Proteasome PF00227.21 KUM57445.1 - 3.2e-41 140.6 0.0 3.7e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit LIP PF03583.9 KUM57446.1 - 1.5e-11 44.0 2.4 1.4e-10 40.9 1.7 2.0 1 1 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 KUM57446.1 - 2.4e-10 40.7 1.3 3.9e-10 40.0 0.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM57446.1 - 5.7e-10 39.1 0.2 1e-09 38.3 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KUM57446.1 - 9.7e-06 24.9 0.2 0.015 14.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF3405 PF11885.3 KUM57447.1 - 5.3e-223 740.7 0.4 6.3e-223 740.4 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Pyr_redox_3 PF13738.1 KUM57448.1 - 1.3e-14 54.7 0.0 3.4e-14 53.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KUM57448.1 - 7.8e-14 50.7 0.0 1.3e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 KUM57448.1 - 4.4e-08 33.0 0.0 1.3e-07 31.5 0.0 1.8 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KUM57448.1 - 3.5e-07 30.3 0.0 0.0039 17.0 0.0 3.6 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM57448.1 - 2.8e-06 27.2 0.0 2.2e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KUM57448.1 - 6.2e-05 22.0 0.5 0.0049 15.8 0.1 3.0 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 KUM57448.1 - 0.0009 19.5 0.1 0.38 11.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KUM57448.1 - 0.025 13.6 0.1 0.16 10.9 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 KUM57448.1 - 0.057 12.2 0.1 0.28 10.0 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 KUM57448.1 - 0.063 11.7 0.3 0.35 9.3 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 KUM57448.1 - 0.071 12.1 0.0 0.36 9.8 0.0 1.9 2 0 0 2 2 2 0 Thi4 family zf-RING_5 PF14634.1 KUM57449.1 - 0.0013 18.4 5.9 0.004 16.8 4.2 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KUM57449.1 - 0.0088 15.6 6.1 0.047 13.3 4.2 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 KUM57449.1 - 0.076 12.7 2.4 0.14 11.9 1.6 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_2 PF13923.1 KUM57449.1 - 0.096 12.7 9.8 0.41 10.7 6.5 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KUM57449.1 - 0.24 11.1 0.3 0.24 11.1 0.2 2.2 3 0 0 3 3 3 0 RING-type zinc-finger zf-C3HC4_3 PF13920.1 KUM57449.1 - 0.28 10.9 7.8 0.72 9.5 5.4 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KUM57449.1 - 0.75 9.7 6.4 0.4 10.6 1.8 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KUM57449.1 - 3.5 7.5 9.7 22 4.9 6.9 2.2 1 1 1 2 2 2 0 Ring finger domain zf-Apc11 PF12861.2 KUM57449.1 - 4.2 7.2 5.8 2.4 8.0 1.8 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Asp PF00026.18 KUM57450.1 - 2.6e-06 26.9 0.0 5e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease SKG6 PF08693.5 KUM57450.1 - 0.0051 16.0 0.2 0.011 14.9 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rax2 PF12768.2 KUM57450.1 - 0.037 13.2 0.0 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Herpes_gE PF02480.11 KUM57450.1 - 0.078 11.2 0.0 0.16 10.2 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TauD PF02668.11 KUM57451.1 - 4.8e-34 118.1 0.1 8.3e-34 117.4 0.1 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KUM57451.1 - 0.056 12.3 0.0 0.12 11.2 0.0 1.5 2 0 0 2 2 2 0 CsiD MFS_1 PF07690.11 KUM57452.1 - 0.046 12.4 0.0 0.058 12.1 0.0 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily SieB PF14163.1 KUM57454.1 - 0.0047 16.5 3.7 0.0087 15.6 2.6 1.5 1 0 0 1 1 1 1 Superinfection exclusion protein B PufQ PF05398.6 KUM57454.1 - 0.026 14.5 2.6 0.95 9.5 0.3 2.4 1 1 1 2 2 2 0 PufQ cytochrome subunit CorA PF01544.13 KUM57454.1 - 0.5 9.3 4.1 0.99 8.3 2.9 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Arf PF00025.16 KUM57455.1 - 6.2e-79 263.2 0.1 7.1e-79 263.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KUM57455.1 - 5.2e-15 55.1 0.0 6.5e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KUM57455.1 - 3.3e-13 49.3 0.0 3.7e-13 49.1 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KUM57455.1 - 3.9e-12 45.5 1.5 2.2e-09 36.4 0.2 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KUM57455.1 - 5.8e-11 41.9 0.0 6.8e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KUM57455.1 - 2e-08 34.7 0.0 2.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KUM57455.1 - 2.9e-06 27.2 0.0 3.9e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KUM57455.1 - 0.011 14.7 0.3 0.02 14.0 0.2 1.6 1 1 0 1 1 1 0 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 KUM57455.1 - 0.011 15.1 0.1 0.078 12.4 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 KUM57455.1 - 0.062 13.1 0.1 0.11 12.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain OTCace_N PF02729.16 KUM57457.1 - 0.099 12.2 0.3 0.19 11.3 0.2 1.4 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain UCH PF00443.24 KUM57457.1 - 0.12 11.4 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L1 PF00687.16 KUM57458.1 - 6.4e-50 169.5 1.9 7.8e-50 169.2 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DEK_C PF08766.6 KUM57458.1 - 0.001 18.8 0.9 0.004 16.8 0.0 2.2 2 0 0 2 2 2 1 DEK C terminal domain MFS_1 PF07690.11 KUM57459.1 - 1.2e-17 63.6 14.6 1.2e-17 63.6 10.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2530 PF10745.4 KUM57459.1 - 0.0067 16.3 1.1 0.0067 16.3 0.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2530) DUF2142 PF09913.4 KUM57459.1 - 0.2 10.2 10.4 0.1 11.2 5.6 1.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2142) Tmemb_cc2 PF10267.4 KUM57459.1 - 0.34 9.4 0.7 0.48 8.9 0.5 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Fic PF02661.13 KUM57461.1 - 4.8e-17 62.4 0.1 3e-16 59.8 0.0 2.4 2 1 1 3 3 3 1 Fic/DOC family PRP1_N PF06424.7 KUM57461.1 - 0.16 12.3 0.1 5.4 7.3 0.0 2.4 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal DUF4239 PF14023.1 KUM57462.1 - 0.065 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) EF-1_beta_acid PF10587.4 KUM57462.1 - 3.1 8.0 11.7 2.6 8.2 0.7 2.6 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region Bromodomain PF00439.20 KUM57463.1 - 1.7e-15 56.7 0.0 3.1e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Bromodomain RNase_H_2 PF13482.1 KUM57463.1 - 0.14 11.9 0.1 0.22 11.3 0.1 1.2 1 0 0 1 1 1 0 RNase_H superfamily DUF3844 PF12955.2 KUM57464.1 - 1.3e-37 128.0 6.0 2e-37 127.3 4.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.8 KUM57464.1 - 0.56 10.4 10.4 2.2 8.5 7.2 1.9 1 1 0 1 1 1 0 EGF-like domain zf-RING_2 PF13639.1 KUM57465.1 - 2.8e-13 49.4 6.1 4.5e-13 48.7 4.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KUM57465.1 - 1.2e-07 31.3 3.9 1.8e-07 30.6 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KUM57465.1 - 1e-06 28.7 4.8 2.1e-06 27.7 3.3 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KUM57465.1 - 2.5e-06 27.1 3.5 3.9e-06 26.4 2.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KUM57465.1 - 7.4e-06 25.8 5.7 1.2e-05 25.1 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KUM57465.1 - 9e-05 22.0 2.4 0.00014 21.4 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KUM57465.1 - 0.0015 18.2 2.7 0.0043 16.8 1.9 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 KUM57465.1 - 0.044 13.6 4.9 0.092 12.6 3.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KUM57465.1 - 0.045 13.3 6.4 0.075 12.6 4.4 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 KUM57465.1 - 0.12 12.1 5.4 0.23 11.1 3.7 1.5 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.2 KUM57465.1 - 0.65 10.0 5.6 1.2 9.2 3.8 1.5 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 KUM57465.1 - 0.72 9.8 3.7 2 8.4 2.6 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain HSP70 PF00012.15 KUM57468.1 - 2.3e-228 759.0 6.8 2.6e-228 758.8 4.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KUM57468.1 - 1.8e-16 59.6 0.5 6.6e-16 57.8 0.1 1.8 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 KUM57468.1 - 0.00054 19.6 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BACON PF13004.2 KUM57468.1 - 0.025 14.7 0.0 0.12 12.6 0.0 2.2 1 0 0 1 1 1 0 Bacteroidetes-Associated Carbohydrate-binding Often N-terminal ATP-synt_DE PF00401.15 KUM57468.1 - 0.068 13.0 0.2 2.5 8.0 0.0 2.7 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain NAF PF03822.9 KUM57468.1 - 0.37 10.5 3.8 0.84 9.3 0.2 2.7 2 0 0 2 2 2 0 NAF domain Fungal_trans PF04082.13 KUM57469.1 - 9.7e-08 31.1 0.2 1.9e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM57469.1 - 2.9e-06 27.0 8.5 5.3e-06 26.2 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA-synt_2c PF01411.14 KUM57470.1 - 3e-215 715.6 0.0 4.9e-215 715.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KUM57470.1 - 4.1e-17 61.7 0.5 9.3e-17 60.6 0.3 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 KUM57470.1 - 0.00085 18.9 1.6 0.0021 17.7 1.1 1.7 1 0 0 1 1 1 1 DHHA1 domain Pro_isomerase PF00160.16 KUM57471.1 - 5.6e-46 156.5 1.7 6.2e-46 156.4 1.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRF PF01765.14 KUM57472.1 - 1.3e-39 135.3 1.5 1.6e-39 134.9 1.0 1.1 1 0 0 1 1 1 1 Ribosome recycling factor MSC PF09402.5 KUM57472.1 - 0.1 11.2 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain PcfJ PF14284.1 KUM57472.1 - 0.1 12.0 2.1 0.18 11.2 1.5 1.4 1 0 0 1 1 1 0 PcfJ-like protein Syntaxin PF00804.20 KUM57472.1 - 0.32 11.1 4.8 2.9 8.1 1.2 2.5 2 0 0 2 2 2 0 Syntaxin CKS PF01111.14 KUM57473.1 - 2.3e-36 123.4 0.5 2.3e-36 123.4 0.3 1.6 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit Erf4 PF10256.4 KUM57475.1 - 0.014 15.2 0.0 0.055 13.3 0.0 1.8 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family AMP-binding PF00501.23 KUM57477.1 - 1.6e-27 95.9 0.0 2.1e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme NinB PF05772.7 KUM57477.1 - 0.025 14.2 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 NinB protein AMP-binding PF00501.23 KUM57478.1 - 3.8e-47 160.6 0.0 5e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KUM57478.1 - 5.5e-11 43.2 0.0 9e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.13 KUM57479.1 - 5.6e-19 68.0 0.0 1e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM57479.1 - 1.1e-05 25.2 9.2 2.1e-05 24.3 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2655 PF10848.3 KUM57479.1 - 0.077 12.8 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2655) Nucleo_P87 PF07267.6 KUM57480.1 - 0.82 8.2 11.4 0.11 11.2 4.5 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 PBP1_TM PF14812.1 KUM57480.1 - 3.5 7.9 19.3 14 6.0 0.3 2.9 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FancD2 PF14631.1 KUM57480.1 - 5.5 3.9 3.9 7.6 3.4 2.7 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DUF1764 PF08576.5 KUM57480.1 - 8.6 7.2 14.7 1.1 10.1 5.9 2.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Srg PF02118.16 KUM57481.1 - 0.0038 16.7 2.9 0.0043 16.5 2.0 1.0 1 0 0 1 1 1 1 Srg family chemoreceptor Sdh_cyt PF01127.17 KUM57481.1 - 0.22 11.3 1.0 0.31 10.8 0.6 1.3 1 1 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF4131 PF13567.1 KUM57481.1 - 7.9 5.8 6.0 9.5 5.5 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) PMT PF02366.13 KUM57482.1 - 4.4e-84 281.6 17.5 7.4e-84 280.9 12.1 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KUM57482.1 - 4.1e-22 78.6 0.4 8.8e-22 77.5 0.2 1.6 1 1 0 1 1 1 1 MIR domain PMT_2 PF13231.1 KUM57482.1 - 0.00069 19.5 13.0 0.00069 19.5 9.0 4.3 4 1 1 5 5 5 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Fascin PF06268.8 KUM57482.1 - 0.14 12.2 0.0 12 6.0 0.0 2.4 2 0 0 2 2 2 0 Fascin domain MFS_1 PF07690.11 KUM57483.1 - 3e-31 108.4 33.8 3e-31 108.4 23.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM57483.1 - 0.00041 19.0 27.3 0.00083 18.0 18.9 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter FKBP_N PF01346.13 KUM57484.1 - 0.062 13.3 1.7 0.11 12.5 0.5 1.8 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase RNA_pol_L_2 PF13656.1 KUM57485.1 - 1.8e-23 81.7 0.0 2.9e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KUM57485.1 - 1.4e-11 43.3 0.0 2.3e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain EF-hand_4 PF12763.2 KUM57486.1 - 1.1e-26 92.5 0.0 4e-14 52.2 0.0 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.6 KUM57486.1 - 1.8e-08 34.2 153.5 0.00017 21.5 22.3 7.5 4 2 3 7 7 7 6 Domain of unknown function (DUF1720) EF-hand_7 PF13499.1 KUM57486.1 - 2.7e-05 24.2 0.3 0.00055 20.0 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KUM57486.1 - 0.11 12.3 0.3 21 5.3 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain HMG_box_2 PF09011.5 KUM57487.1 - 1.7e-12 47.4 2.0 5.2e-10 39.5 0.0 2.9 2 1 0 2 2 2 2 HMG-box domain HMG_box PF00505.14 KUM57487.1 - 3.2e-11 43.3 4.5 2.1e-09 37.5 0.7 3.1 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_5 PF14887.1 KUM57487.1 - 0.0014 18.3 0.8 0.0028 17.4 0.0 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box 5 DUF2744 PF10910.3 KUM57487.1 - 0.11 12.3 0.1 0.11 12.3 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2744) ApoO PF09769.4 KUM57487.1 - 0.14 11.8 3.1 1.1 9.0 2.1 2.2 1 1 0 1 1 1 0 Apolipoprotein O DEAD PF00270.24 KUM57488.1 - 4.3e-43 146.7 0.0 2.2e-42 144.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM57488.1 - 6.3e-25 86.8 0.0 2.4e-24 84.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KUM57488.1 - 0.0058 15.4 0.0 0.009 14.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Metaviral_G PF09595.5 KUM57489.1 - 0.72 9.4 7.1 0.8 9.3 4.9 1.1 1 0 0 1 1 1 0 Metaviral_G glycoprotein DUF996 PF06195.8 KUM57490.1 - 0.017 15.1 0.8 0.041 13.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF996) UPF0016 PF01169.14 KUM57490.1 - 4.7 7.4 11.6 0.2 11.8 1.5 3.4 4 1 0 4 4 4 0 Uncharacterized protein family UPF0016 DUF1071 PF06378.6 KUM57491.1 - 0.028 13.5 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) DUF3134 PF11332.3 KUM57491.1 - 0.043 13.9 0.0 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3134) GP41 PF00517.12 KUM57491.1 - 0.044 13.3 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 Retroviral envelope protein Dynamin_N PF00350.18 KUM57492.1 - 2.1e-28 99.2 0.1 4.7e-28 98.1 0.1 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KUM57492.1 - 3.1e-14 52.4 0.0 9.7e-14 50.8 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 KUM57492.1 - 0.0017 18.3 0.1 0.012 15.5 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KUM57492.1 - 0.0049 17.3 0.0 0.012 16.0 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Spo0A_C PF08769.6 KUM57492.1 - 0.068 13.0 0.1 0.22 11.3 0.0 2.0 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal EPV_E5 PF08135.6 KUM57493.1 - 0.042 13.8 4.8 0.06 13.3 3.3 1.2 1 0 0 1 1 1 0 Major transforming protein E5 family Dehydrin PF00257.14 KUM57494.1 - 0.078 13.2 12.9 0.087 13.1 8.4 1.4 1 1 0 1 1 1 0 Dehydrin zf-C2H2 PF00096.21 KUM57495.1 - 6.4e-21 73.3 38.4 9.5e-06 25.6 3.0 8.2 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KUM57495.1 - 3e-17 61.9 36.5 2.1e-07 30.8 1.6 7.5 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 KUM57495.1 - 1.9e-07 30.9 58.7 0.0016 18.6 1.2 8.3 8 0 0 8 8 8 5 C2H2-type zinc finger zf-met PF12874.2 KUM57495.1 - 4.8e-06 26.5 17.8 0.004 17.2 0.1 5.5 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KUM57495.1 - 5.2e-06 26.4 19.8 0.0029 17.7 0.2 5.3 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KUM57495.1 - 0.0089 15.8 1.3 0.0089 15.8 0.9 5.1 5 0 0 5 5 5 2 C2H2-type zinc finger DUF2580 PF10824.3 KUM57496.1 - 0.028 14.7 1.7 0.7 10.2 0.8 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF2580) DUF3376 PF11856.3 KUM57496.1 - 0.032 13.6 2.0 0.037 13.4 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3376) FCD PF07729.7 KUM57496.1 - 0.043 14.1 0.3 0.043 14.1 0.2 2.1 3 0 0 3 3 3 0 FCD domain PRA-PH PF01503.12 KUM57496.1 - 1.2 9.4 4.1 0.49 10.7 0.3 2.1 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase zf-HC5HC2H_2 PF13832.1 KUM57498.1 - 4.7e-32 110.2 5.2 4.7e-32 110.2 3.6 2.2 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.4 KUM57498.1 - 2.2e-30 106.0 0.0 4.5e-30 105.0 0.0 1.6 1 0 0 1 1 1 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.1 KUM57498.1 - 1.6e-26 92.2 1.8 1.6e-26 92.2 1.3 2.9 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 KUM57498.1 - 5.1e-15 54.5 8.9 6.6e-14 50.9 1.7 2.6 2 0 0 2 2 2 2 PHD-finger PHD PF00628.24 KUM57498.1 - 7.3e-10 38.3 20.0 5.3e-08 32.4 6.7 2.6 2 0 0 2 2 2 2 PHD-finger mRNA_cap_C PF03919.10 KUM57498.1 - 0.068 13.5 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain C1_1 PF00130.17 KUM57498.1 - 0.39 10.4 19.4 0.038 13.7 1.2 2.8 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.6 KUM57498.1 - 1.5 8.9 19.3 0.024 14.6 2.1 2.6 2 0 0 2 2 2 0 RING-like domain Prok-RING_1 PF14446.1 KUM57498.1 - 2.1 8.1 14.6 1.7 8.4 4.2 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 RRM_1 PF00076.17 KUM57500.1 - 2.8e-20 71.7 0.0 3.8e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM57500.1 - 1e-16 60.6 0.0 1.3e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM57500.1 - 7.6e-12 44.9 0.0 1e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M22 PF00814.20 KUM57501.1 - 4.3e-43 147.7 0.0 3.4e-42 144.8 0.0 2.1 1 1 0 1 1 1 1 Glycoprotease family FGGY_C PF02782.11 KUM57501.1 - 0.036 13.6 0.0 0.097 12.2 0.0 1.8 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Esterase PF00756.15 KUM57503.1 - 2.2e-51 174.6 0.0 5e-51 173.5 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.4 KUM57503.1 - 1.1e-06 28.0 0.0 0.00014 21.2 0.0 2.2 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 KUM57503.1 - 1.6e-05 24.6 0.0 2.8e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KUM57503.1 - 0.00022 20.5 0.1 0.0004 19.6 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KUM57503.1 - 0.00052 19.9 0.0 0.00073 19.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KUM57503.1 - 0.0013 17.6 0.0 0.004 16.0 0.0 1.7 1 1 0 1 1 1 1 Chlorophyllase enzyme Lipase_3 PF01764.20 KUM57503.1 - 0.013 15.1 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.15 KUM57503.1 - 0.034 13.7 0.1 0.29 10.6 0.0 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold PGAP1 PF07819.8 KUM57503.1 - 0.073 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein AXE1 PF05448.7 KUM57503.1 - 0.073 11.5 0.0 0.35 9.3 0.0 1.8 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Chlorophyllase PF07224.6 KUM57503.1 - 0.12 11.1 0.0 0.5 9.1 0.0 1.8 2 0 0 2 2 2 0 Chlorophyllase Abhydrolase_2 PF02230.11 KUM57503.1 - 0.12 11.7 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_C50 PF03568.12 KUM57504.1 - 5e-127 423.7 0.0 1e-126 422.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.1 KUM57504.1 - 1.4e-06 28.1 16.9 0.011 15.6 0.1 6.3 5 1 0 6 6 6 3 Tetratricopeptide repeat CHAT PF12770.2 KUM57504.1 - 5.2e-06 25.8 0.6 0.00078 18.6 0.0 3.2 2 1 0 2 2 2 1 CHAT domain TPR_2 PF07719.12 KUM57504.1 - 0.00021 20.9 10.7 1.1 9.3 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 KUM57504.1 - 0.00082 18.9 6.3 1.2 8.8 0.0 5.3 5 1 0 6 6 6 2 TPR repeat TPR_14 PF13428.1 KUM57504.1 - 0.0019 18.6 12.0 8.7 7.2 0.0 7.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.1 KUM57504.1 - 0.0049 16.7 0.3 4.9 7.2 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KUM57504.1 - 0.029 13.9 2.7 15 5.3 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 KUM57504.1 - 0.094 12.5 0.2 47 4.0 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Mito_carr PF00153.22 KUM57505.1 - 2.9e-74 244.8 0.1 1.5e-25 88.6 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 KUM57505.1 - 7.3e-13 46.8 4.5 1.6e-06 26.9 0.1 5.1 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.1 KUM57505.1 - 1.2e-12 46.5 5.9 1.2e-06 27.8 0.1 5.2 5 0 0 5 5 5 2 EF-hand domain EF-hand_7 PF13499.1 KUM57505.1 - 8.5e-11 41.8 5.5 7.7e-07 29.1 1.0 4.0 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.1 KUM57505.1 - 4e-10 39.1 4.4 0.66 9.6 0.0 5.3 3 2 2 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.1 KUM57505.1 - 1.5e-08 33.5 7.1 1.7e-05 23.9 0.2 4.3 5 0 0 5 5 5 2 EF hand Auxin_repressed PF05564.7 KUM57507.1 - 0.38 11.3 3.6 0.47 11.0 2.5 1.3 1 0 0 1 1 1 0 Dormancy/auxin associated protein Homeobox PF00046.24 KUM57508.1 - 2.3e-16 59.1 2.4 2.3e-16 59.1 1.7 2.2 3 0 0 3 3 3 1 Homeobox domain Homeobox_KN PF05920.6 KUM57508.1 - 8.9e-07 28.5 0.4 2.3e-06 27.1 0.2 1.7 1 0 0 1 1 1 1 Homeobox KN domain HAD_2 PF13419.1 KUM57509.1 - 1.3e-17 64.6 0.0 1.5e-17 64.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KUM57509.1 - 4.4e-09 37.0 0.0 2.9e-07 31.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KUM57509.1 - 1e-07 31.5 0.0 1.9e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 KUM57509.1 - 0.0017 18.5 0.0 0.003 17.7 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase CRC_subunit PF08624.5 KUM57512.1 - 1.8e-47 160.7 0.1 2.5e-47 160.2 0.1 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit His_Phos_1 PF00300.17 KUM57515.1 - 2e-13 50.6 0.0 3.1e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MMR_HSR1 PF01926.18 KUM57517.1 - 1.1e-22 80.1 0.2 2.3e-15 56.5 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase GN3L_Grn1 PF08701.6 KUM57517.1 - 1.2e-21 76.3 18.0 1.2e-21 76.3 12.5 2.0 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase GTP_EFTU PF00009.22 KUM57517.1 - 2.3e-06 27.1 0.1 0.074 12.4 0.0 2.7 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KUM57517.1 - 5.4e-06 26.3 6.6 0.16 11.7 0.0 4.3 3 2 2 5 5 5 2 Dynamin family FeoB_N PF02421.13 KUM57517.1 - 1.8e-05 24.0 0.1 0.00022 20.5 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 KUM57517.1 - 0.00092 18.4 0.3 0.00092 18.4 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 KUM57517.1 - 0.0015 19.0 2.8 0.32 11.4 0.0 3.3 3 0 0 3 3 3 1 Miro-like protein AIG1 PF04548.11 KUM57517.1 - 0.0074 15.4 0.0 0.21 10.6 0.0 2.6 2 0 0 2 2 2 1 AIG1 family ArgK PF03308.11 KUM57517.1 - 0.011 14.5 0.1 0.011 14.5 0.0 2.1 2 0 0 2 2 2 0 ArgK protein Arf PF00025.16 KUM57517.1 - 0.072 12.3 0.0 0.96 8.6 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_16 PF13191.1 KUM57517.1 - 0.088 12.7 0.8 0.62 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 KUM57517.1 - 0.15 12.3 0.0 0.15 12.3 0.0 2.5 2 1 0 2 2 1 0 AAA domain SAPS PF04499.10 KUM57517.1 - 0.28 9.7 3.4 0.39 9.2 2.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein AAA_17 PF13207.1 KUM57517.1 - 0.28 12.0 0.0 0.28 12.0 0.0 2.8 2 1 0 2 2 2 0 AAA domain Nop14 PF04147.7 KUM57517.1 - 5 4.9 25.6 10 3.9 17.8 1.4 1 0 0 1 1 1 0 Nop14-like family CBFD_NFYB_HMF PF00808.18 KUM57518.1 - 2.5e-05 24.2 0.0 4.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KUM57518.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Sporozoite_P67 PF05642.6 KUM57518.1 - 0.31 8.8 7.4 0.58 7.9 5.1 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen TFIIA PF03153.8 KUM57518.1 - 1.4 8.7 17.1 2.3 8.0 11.9 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SIR2 PF02146.12 KUM57519.1 - 4.5e-29 101.4 0.0 1e-28 100.2 0.0 1.6 1 1 0 1 1 1 1 Sir2 family Chorismate_synt PF01264.16 KUM57520.1 - 4.8e-65 219.3 0.0 5.7e-65 219.0 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Kelch_4 PF13418.1 KUM57521.1 - 2.6e-08 33.4 1.1 0.029 14.1 0.0 4.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 KUM57521.1 - 4.9e-06 26.4 1.5 2.6 8.3 0.0 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.1 KUM57521.1 - 0.00033 20.5 0.0 0.043 13.7 0.0 3.7 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 KUM57521.1 - 0.0043 16.7 1.4 0.37 10.6 0.0 3.9 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.20 KUM57521.1 - 0.0066 15.9 0.0 3.7 7.1 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 KUM57521.1 - 0.017 15.2 12.3 0.75 10.0 0.0 5.4 6 1 0 6 6 6 0 Galactose oxidase, central domain MFS_1 PF07690.11 KUM57522.1 - 1.5e-31 109.4 56.1 1.5e-31 109.4 38.9 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM57522.1 - 8.6e-11 40.7 16.6 1.1e-10 40.3 11.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Hemerythrin PF01814.18 KUM57523.1 - 7.7e-13 48.7 0.2 1.1e-12 48.2 0.1 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain TRF PF08558.5 KUM57523.1 - 0.02 14.2 0.6 0.031 13.6 0.1 1.6 2 0 0 2 2 2 0 Telomere repeat binding factor (TRF) Peptidase_C65 PF10275.4 KUM57523.1 - 0.033 13.5 0.1 0.056 12.7 0.1 1.3 1 0 0 1 1 1 0 Peptidase C65 Otubain KGG PF10685.4 KUM57524.1 - 3.9e-23 80.8 19.6 2.9e-09 36.6 0.3 3.1 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif LEA_5 PF00477.12 KUM57524.1 - 0.013 15.7 2.1 0.23 11.7 1.8 1.8 1 1 1 2 2 2 0 Small hydrophilic plant seed protein VanY PF02557.12 KUM57524.1 - 0.11 12.3 3.3 0.11 12.3 0.6 1.8 1 1 1 2 2 2 0 D-alanyl-D-alanine carboxypeptidase BBE PF08031.7 KUM57525.1 - 2.4e-06 27.3 0.1 3.6e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Berberine and berberine like Pkinase PF00069.20 KUM57527.1 - 1.1e-53 181.9 0.1 1.1e-36 126.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KUM57527.1 - 3.2e-27 95.2 0.0 4.5e-26 91.4 0.0 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM57527.1 - 8.4e-05 21.6 0.0 0.00026 20.0 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KUM57527.1 - 0.0021 17.8 1.1 0.035 13.8 0.8 2.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RicinB_lectin_2 PF14200.1 KUM57528.1 - 1.1e-12 48.2 0.0 6.9e-10 39.2 0.0 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 KUM57528.1 - 0.00012 22.0 0.0 0.00015 21.7 0.0 1.1 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain DUF569 PF04601.8 KUM57528.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF569) SIR2 PF02146.12 KUM57529.1 - 1.2e-60 204.2 0.0 1.6e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 KUM57529.1 - 0.002 17.6 0.0 0.0038 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 KUM57529.1 - 0.0043 16.7 0.0 2.8 7.6 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain TPR_12 PF13424.1 KUM57530.1 - 2.3e-09 37.0 5.9 1.4e-07 31.3 0.1 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KUM57530.1 - 5.5e-09 35.2 0.4 0.0057 16.4 0.0 5.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 KUM57530.1 - 4.3e-08 32.6 0.7 0.0014 18.2 0.0 4.5 3 2 1 4 4 4 2 TPR repeat TPR_8 PF13181.1 KUM57530.1 - 5e-08 32.1 0.0 0.00085 18.9 0.0 3.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KUM57530.1 - 5.1e-08 33.1 11.9 0.00027 21.2 0.4 4.1 4 1 1 5 5 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 KUM57530.1 - 2.4e-07 31.2 9.9 0.037 14.7 0.1 4.6 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KUM57530.1 - 2.3e-06 27.7 9.0 0.43 11.3 0.5 5.7 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 KUM57530.1 - 8e-05 22.5 0.0 13 6.2 0.0 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 KUM57530.1 - 0.00019 20.8 0.1 0.057 13.0 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KUM57530.1 - 0.0021 17.7 2.5 0.26 11.1 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 KUM57530.1 - 0.0036 17.1 11.4 0.31 10.9 0.5 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat Vps39_1 PF10366.4 KUM57530.1 - 0.02 14.8 0.5 0.22 11.5 0.1 2.3 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 ChAPs PF09295.5 KUM57530.1 - 0.028 13.1 0.5 1.2 7.8 0.1 2.3 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.9 KUM57530.1 - 0.071 13.5 0.1 0.071 13.5 0.1 4.0 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_21 PF09976.4 KUM57530.1 - 0.15 11.9 4.2 0.27 11.1 0.1 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KUM57530.1 - 0.32 11.5 8.4 72 4.1 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 KUM57530.1 - 0.39 10.7 3.9 0.83 9.6 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat RWD PF05773.17 KUM57532.1 - 8.2e-24 83.6 0.3 1.7e-23 82.6 0.2 1.5 1 0 0 1 1 1 1 RWD domain N_Asn_amidohyd PF14736.1 KUM57532.1 - 0.051 12.4 0.0 0.069 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein N-terminal asparagine amidohydrolase GvpL_GvpF PF06386.6 KUM57532.1 - 4.9 6.6 9.3 11 5.4 6.4 1.6 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Peptidase_S49_N PF08496.5 KUM57532.1 - 5.9 6.6 10.1 9 6.0 6.8 1.4 1 1 0 1 1 1 0 Peptidase family S49 N-terminal IBP39 PF11422.3 KUM57534.1 - 0.0049 16.3 10.4 0.021 14.3 0.6 2.8 2 1 1 3 3 3 2 Initiator binding protein 39 kDa Lantibiotic_a PF14867.1 KUM57534.1 - 4.2 6.7 5.5 23 4.3 0.1 2.9 3 0 0 3 3 3 0 Lantibiotic alpha Methyltransf_26 PF13659.1 KUM57535.1 - 3.3e-10 40.0 0.0 6.4e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 KUM57535.1 - 8.3e-09 35.2 0.0 1.7e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.11 KUM57535.1 - 0.07 12.1 0.0 0.15 11.1 0.0 1.4 1 1 0 1 1 1 0 N-6 DNA Methylase N6_N4_Mtase PF01555.13 KUM57535.1 - 0.073 12.5 0.0 0.48 9.8 0.0 2.1 2 0 0 2 2 2 0 DNA methylase Fungal_trans PF04082.13 KUM57536.1 - 6.7e-21 74.3 0.2 1.2e-20 73.4 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM57536.1 - 1.2e-09 37.8 9.8 2.4e-09 36.9 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L2_C PF03947.13 KUM57537.1 - 5.5e-45 152.3 4.7 2e-32 111.6 0.3 3.0 3 1 1 4 4 4 2 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KUM57537.1 - 5e-25 87.2 0.1 9.4e-25 86.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PAS PF00989.19 KUM57537.1 - 0.079 12.7 0.2 0.2 11.4 0.1 1.6 2 0 0 2 2 2 0 PAS fold Cyclin_N PF00134.18 KUM57538.1 - 4.8e-45 152.2 0.2 3.2e-44 149.5 0.0 2.2 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KUM57538.1 - 1e-34 118.9 0.0 1.9e-34 118.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Ribonuc_P_40 PF08584.6 KUM57539.1 - 2.9e-91 305.3 0.0 3.6e-91 305.0 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit WD40 PF00400.27 KUM57540.1 - 4.6e-35 118.2 10.1 8.1e-10 38.1 0.0 7.0 7 1 0 7 7 7 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KUM57540.1 - 1.2e-08 33.6 0.0 4.1e-06 25.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.6 KUM57540.1 - 2.1e-05 24.3 0.1 0.048 13.3 0.0 3.2 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 KUM57540.1 - 0.00053 19.4 0.0 0.033 13.6 0.0 3.1 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.3 KUM57540.1 - 0.0027 15.9 0.2 0.046 11.8 0.0 2.1 1 1 1 2 2 2 1 Nucleoporin Nup120/160 TFIIIC_delta PF12657.2 KUM57540.1 - 0.09 12.4 0.2 2.7 7.6 0.0 3.1 3 0 0 3 3 3 0 Transcription factor IIIC subunit delta N-term Zn_clus PF00172.13 KUM57541.1 - 3.5e-08 33.2 5.6 7.4e-08 32.1 3.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PBP PF01161.15 KUM57542.1 - 2.3e-15 56.7 0.0 2.8e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein GFA PF04828.9 KUM57543.1 - 7.9e-22 77.0 0.0 1.2e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 KUM57543.1 - 0.065 12.4 0.1 0.28 10.4 0.0 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 KUM57543.1 - 0.095 12.2 1.0 0.15 11.5 0.0 1.9 2 0 0 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.1 KUM57543.1 - 0.12 12.0 0.1 0.12 12.0 0.0 2.6 3 0 0 3 3 3 0 Nudix N-terminal SMP PF04927.7 KUM57545.1 - 2.1e-15 56.4 16.7 3e-06 27.1 3.4 3.2 2 1 1 3 3 3 3 Seed maturation protein MFS_1 PF07690.11 KUM57546.1 - 5.7e-46 156.8 24.9 1.1e-45 155.8 17.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM57546.1 - 3.1e-09 35.9 9.6 3.1e-09 35.9 6.7 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KUM57546.1 - 2.9e-06 25.8 4.5 2.9e-06 25.8 3.1 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 KUM57546.1 - 0.00022 20.9 4.0 0.0036 17.0 0.3 3.8 3 1 0 3 3 3 1 MFS_1 like family MFS_3 PF05977.8 KUM57546.1 - 0.00025 19.3 6.4 0.00025 19.3 4.5 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector Citrate_synt PF00285.16 KUM57547.1 - 1.7e-81 273.7 0.0 2.1e-81 273.4 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase UvrC_HhH_N PF08459.6 KUM57547.1 - 0.16 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal Sugar_tr PF00083.19 KUM57548.1 - 3.2e-74 250.1 29.6 3.7e-74 249.9 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM57548.1 - 9.1e-20 70.6 35.8 3.1e-18 65.6 20.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Epimerase PF01370.16 KUM57549.1 - 5e-15 55.5 0.0 7.5e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KUM57549.1 - 6.9e-11 41.3 0.0 1e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KUM57549.1 - 1.4e-10 41.5 0.3 3.6e-10 40.1 0.1 1.8 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 KUM57549.1 - 1.3e-09 37.3 0.1 4.4e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.8 KUM57549.1 - 7e-06 25.4 0.1 1.1e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KUM57549.1 - 0.00079 19.3 0.1 0.004 17.0 0.1 2.1 2 1 0 2 2 2 1 short chain dehydrogenase Saccharop_dh PF03435.13 KUM57549.1 - 0.0048 15.9 0.1 2.2 7.1 0.0 2.2 2 0 0 2 2 2 2 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 KUM57549.1 - 0.098 11.5 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GFA PF04828.9 KUM57550.1 - 1.2e-21 76.4 0.0 1.6e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 KUM57550.1 - 0.022 14.4 0.1 0.022 14.4 0.1 2.2 2 0 0 2 2 2 0 Nudix N-terminal PBP PF01161.15 KUM57551.1 - 7.1e-21 74.5 0.0 8.6e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ribosomal_L23 PF00276.15 KUM57551.1 - 0.088 12.7 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L23 ATG22 PF11700.3 KUM57555.1 - 3.4e-152 507.2 14.4 3.8e-152 507.1 10.0 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KUM57555.1 - 0.00013 20.8 21.3 0.00013 20.8 14.8 3.1 2 1 0 3 3 3 2 Major Facilitator Superfamily IncA PF04156.9 KUM57555.1 - 9 5.8 7.8 0.26 10.8 0.6 2.0 1 1 0 2 2 2 0 IncA protein BAR PF03114.13 KUM57556.1 - 4e-51 173.7 5.8 1.1e-50 172.2 1.0 2.1 2 0 0 2 2 2 2 BAR domain DUF3340 PF11818.3 KUM57556.1 - 0.059 13.3 1.2 0.12 12.2 0.8 1.6 1 1 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) eIF-6 PF01912.13 KUM57558.1 - 5e-82 273.8 1.0 6.4e-82 273.4 0.7 1.1 1 0 0 1 1 1 1 eIF-6 family Desmo_N PF06771.6 KUM57560.1 - 0.068 13.1 0.1 0.2 11.6 0.0 1.7 1 1 1 2 2 2 0 Viral Desmoplakin N-terminus Pept_tRNA_hydro PF01195.14 KUM57561.1 - 6.9e-18 64.7 0.0 0.00012 21.6 0.0 3.1 2 1 1 3 3 3 3 Peptidyl-tRNA hydrolase Pkinase PF00069.20 KUM57562.1 - 1.3e-62 211.3 0.0 2e-62 210.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM57562.1 - 5e-26 91.3 0.0 7.9e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KUM57562.1 - 0.0071 15.4 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KUM57562.1 - 0.014 14.3 0.0 0.028 13.3 0.0 1.6 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KUM57562.1 - 0.018 14.7 0.8 1.7 8.2 0.0 3.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Sybindin PF04099.7 KUM57563.1 - 8.6e-17 61.1 0.1 9.6e-17 61.0 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 KUM57563.1 - 0.0039 17.0 0.1 0.0046 16.8 0.1 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region RNA_polI_A14 PF08203.6 KUM57564.1 - 0.54 10.5 3.5 0.89 9.8 0.1 2.6 3 0 0 3 3 3 0 Yeast RNA polymerase I subunit RPA14 AT_hook PF02178.14 KUM57565.1 - 0.0031 17.0 1.4 0.018 14.6 1.0 2.5 1 0 0 1 1 1 1 AT hook motif Pkinase PF00069.20 KUM57566.1 - 2.4e-56 190.7 0.0 3.7e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM57566.1 - 7.5e-35 120.2 0.0 8.5e-33 113.5 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KUM57566.1 - 2.2e-09 36.6 0.0 2.9e-08 33.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KUM57566.1 - 0.0024 17.6 0.1 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family SET PF00856.23 KUM57568.1 - 1e-20 74.6 0.2 1e-20 74.6 0.2 2.8 2 2 0 2 2 2 1 SET domain SRI PF08236.6 KUM57568.1 - 3.6e-18 65.2 7.5 3.6e-18 65.2 5.2 2.2 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain WW PF00397.21 KUM57568.1 - 8.9e-05 22.2 2.1 0.00021 21.1 1.5 1.7 1 0 0 1 1 1 1 WW domain Med26 PF08711.6 KUM57568.1 - 0.0028 17.1 0.1 0.0093 15.4 0.1 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Pre-SET PF05033.11 KUM57568.1 - 1.4 9.1 11.5 0.34 11.2 5.0 2.3 2 0 0 2 2 2 0 Pre-SET motif PHD PF00628.24 KUM57569.1 - 2.7e-08 33.3 9.1 2.7e-08 33.3 6.3 1.9 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 KUM57569.1 - 0.0064 15.7 5.8 0.0064 15.7 4.0 2.0 2 0 0 2 2 2 1 PHD-finger WHIM2 PF15613.1 KUM57569.1 - 0.042 13.7 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 Prefoldin_2 PF01920.15 KUM57570.1 - 8.4e-18 64.0 6.0 1e-17 63.7 4.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit BLOC1_2 PF10046.4 KUM57570.1 - 0.032 14.3 0.8 0.032 14.3 0.5 1.9 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3375 PF11855.3 KUM57570.1 - 0.097 11.3 2.4 0.3 9.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3375) DUF641 PF04859.7 KUM57570.1 - 1.3 8.8 5.2 3.1 7.5 0.2 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF4200 PF13863.1 KUM57570.1 - 2.4 8.1 9.9 6.7 6.6 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) OmpH PF03938.9 KUM57570.1 - 2.7 7.8 9.5 5.9 6.7 6.6 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2681 PF10883.3 KUM57570.1 - 3.1 8.0 6.9 0.46 10.7 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Sigma54_AID PF00309.15 KUM57570.1 - 3.3 7.2 8.0 0.62 9.5 2.5 2.0 2 0 0 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) HMG_box PF00505.14 KUM57571.1 - 2e-11 44.0 0.2 4.1e-11 42.9 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KUM57571.1 - 0.048 14.0 0.1 0.048 14.0 0.1 1.9 2 0 0 2 2 2 0 HMG-box domain Rcd1 PF04078.8 KUM57572.1 - 7.4e-131 434.7 2.3 9.1e-131 434.4 1.6 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like PAT1 PF09770.4 KUM57572.1 - 7.7 4.6 18.3 9.7 4.2 12.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Abhydrolase_6 PF12697.2 KUM57574.1 - 2.9e-27 96.0 0.0 3.7e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM57574.1 - 6.9e-16 58.4 0.2 2.9e-15 56.4 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KUM57574.1 - 5.5e-07 29.4 0.0 1.4e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KUM57574.1 - 0.00015 21.5 0.0 0.00028 20.6 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase PF07224.6 KUM57574.1 - 0.066 11.9 0.0 0.098 11.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase AXE1 PF05448.7 KUM57574.1 - 0.11 10.9 0.0 0.17 10.3 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) CorA PF01544.13 KUM57576.1 - 7.1e-15 54.7 0.0 8.5e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein AA_permease PF00324.16 KUM57577.1 - 8.1e-118 393.7 41.3 9.9e-118 393.4 28.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KUM57577.1 - 2.6e-31 108.6 43.2 3.4e-31 108.2 29.9 1.1 1 0 0 1 1 1 1 Amino acid permease PMBR PF09373.5 KUM57577.1 - 0.036 14.0 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 Pseudomurein-binding repeat Ribonuclease PF00545.15 KUM57578.1 - 9.2e-18 64.0 0.3 1.2e-17 63.7 0.2 1.2 1 0 0 1 1 1 1 ribonuclease YjbE PF11106.3 KUM57578.1 - 0.17 11.8 3.3 0.29 11.1 2.3 1.3 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE GST_N_3 PF13417.1 KUM57579.1 - 8.5e-15 54.7 0.1 1.6e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KUM57579.1 - 2.5e-11 43.4 0.1 5e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KUM57579.1 - 1.1e-08 35.0 0.1 3.9e-08 33.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KUM57579.1 - 3.9e-08 33.1 0.1 6e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KUM57579.1 - 5.8e-06 26.0 0.0 1.1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KUM57579.1 - 0.00014 22.2 0.0 0.00021 21.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 KUM57579.1 - 0.011 16.1 0.0 0.026 14.9 0.0 1.6 2 0 0 2 2 2 0 MetRS-N binding domain Zn_clus PF00172.13 KUM57580.1 - 0.001 18.9 13.0 0.001 18.9 9.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RhoGAP PF00620.22 KUM57580.1 - 0.077 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 RhoGAP domain Methyltransf_31 PF13847.1 KUM57581.1 - 3.8e-29 101.2 0.0 4.9e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM57581.1 - 5.8e-27 94.0 0.0 1.1e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KUM57581.1 - 7.7e-20 71.0 0.0 1.1e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 KUM57581.1 - 4.2e-17 62.3 0.0 6.1e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM57581.1 - 9.4e-17 61.3 0.0 1.7e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM57581.1 - 6.4e-16 58.9 0.0 9.9e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM57581.1 - 1.9e-14 53.8 0.0 2.9e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KUM57581.1 - 1.5e-09 37.9 0.1 3.6e-09 36.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KUM57581.1 - 1.6e-09 37.3 0.0 2.4e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 KUM57581.1 - 3e-08 33.2 0.0 4.8e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.14 KUM57581.1 - 8.9e-07 28.6 0.0 1.2e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 KUM57581.1 - 1e-05 24.6 0.0 1.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase NodS PF05401.6 KUM57581.1 - 0.00029 20.3 0.0 0.00043 19.7 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.6 KUM57581.1 - 0.00047 18.9 0.0 0.00073 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) GCD14 PF08704.5 KUM57581.1 - 0.0025 17.3 0.0 0.004 16.6 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit DREV PF05219.7 KUM57581.1 - 0.0047 15.8 0.0 0.01 14.7 0.0 1.6 1 1 0 1 1 1 1 DREV methyltransferase CMAS PF02353.15 KUM57581.1 - 0.0056 15.7 0.0 0.0074 15.3 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 KUM57581.1 - 0.0061 16.5 0.0 0.0084 16.1 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase RrnaAD PF00398.15 KUM57581.1 - 0.007 15.4 0.0 0.0094 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PrmA PF06325.8 KUM57581.1 - 0.019 14.0 0.0 0.024 13.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 KUM57581.1 - 0.02 14.5 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 KUM57581.1 - 0.022 13.9 0.0 0.03 13.5 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_8 PF05148.10 KUM57581.1 - 0.038 13.6 0.0 0.44 10.1 0.0 2.0 2 0 0 2 2 2 0 Hypothetical methyltransferase WW PF00397.21 KUM57582.1 - 3.6e-07 29.9 0.4 1.1e-06 28.3 0.3 1.9 1 0 0 1 1 1 1 WW domain Gly-zipper_OmpA PF13436.1 KUM57582.1 - 0.26 10.9 1.9 0.45 10.1 1.3 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DUF1212 PF06738.7 KUM57583.1 - 1.6e-52 177.8 12.7 1.5e-46 158.3 0.4 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KUM57583.1 - 4.8e-28 97.6 9.2 4.8e-28 97.6 6.4 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3815) Na_Ca_ex PF01699.19 KUM57584.1 - 4.7e-40 136.4 33.6 2e-21 76.0 9.8 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein YrzO PF14142.1 KUM57584.1 - 0.098 12.3 0.3 0.21 11.2 0.2 1.5 1 0 0 1 1 1 0 YrzO-like protein Anoctamin PF04547.7 KUM57585.1 - 1.5e-102 343.6 0.5 1.8e-102 343.3 0.3 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel YbgT_YccB PF08173.6 KUM57586.1 - 1.8 8.4 5.1 0.31 10.8 0.7 1.9 2 0 0 2 2 2 0 Membrane bound YbgT-like protein Spc7_N PF15402.1 KUM57587.1 - 0 1016.1 75.9 3.1e-189 631.1 29.5 3.2 1 1 2 3 3 3 2 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 KUM57587.1 - 1.3e-122 408.5 4.7 2.6e-122 407.5 3.3 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF3016 PF11454.3 KUM57587.1 - 0.0088 15.6 0.1 0.024 14.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3016) V_ATPase_I PF01496.14 KUM57587.1 - 9.2 3.9 6.0 15 3.3 4.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1932 PF09130.6 KUM57588.1 - 3.4e-11 42.6 0.0 8.4e-11 41.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) F420_oxidored PF03807.12 KUM57588.1 - 2.5e-06 27.8 0.1 5.5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KUM57588.1 - 1.1e-05 25.3 0.1 3.2e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 KUM57588.1 - 0.0026 16.9 0.0 0.0043 16.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rossmann-like PF10727.4 KUM57588.1 - 0.14 11.8 0.9 1.4 8.6 0.1 2.4 2 0 0 2 2 2 0 Rossmann-like domain Fungal_trans PF04082.13 KUM57589.1 - 1.5e-18 66.6 0.9 3e-18 65.6 0.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM57589.1 - 4.5e-07 29.6 13.1 8.1e-07 28.8 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KUM57592.1 - 1.8e-26 92.5 0.6 3.5e-26 91.6 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KUM57593.1 - 1.2e-38 132.7 28.5 1.2e-38 132.7 19.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 KUM57593.1 - 0.066 11.2 4.7 0.067 11.2 2.0 1.9 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family bZIP_2 PF07716.10 KUM57594.1 - 1.7e-13 50.1 13.2 2.9e-13 49.4 9.1 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KUM57594.1 - 2.6e-05 24.0 14.6 6.8e-05 22.7 10.1 1.6 1 1 0 1 1 1 1 bZIP transcription factor Herpes_BLRF2 PF05812.7 KUM57594.1 - 0.0014 18.4 0.6 0.0014 18.4 0.4 1.9 1 1 0 1 1 1 1 Herpesvirus BLRF2 protein DUF4094 PF13334.1 KUM57594.1 - 0.013 15.8 0.5 0.023 15.0 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Jnk-SapK_ap_N PF09744.4 KUM57594.1 - 0.14 12.1 2.5 0.21 11.5 1.8 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ANTH PF07651.11 KUM57595.1 - 1.5e-58 197.7 0.0 2e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 KUM57595.1 - 2.9e-07 30.4 0.0 2e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 ENTH domain Ribosomal_S17 PF00366.15 KUM57597.1 - 9.2e-30 102.4 1.5 2.1e-29 101.3 1.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S17 Mac PF12464.3 KUM57598.1 - 7.6e-13 48.2 0.0 2e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 KUM57598.1 - 1.3e-09 37.1 9.4 3e-05 23.3 0.3 3.7 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Zn_clus PF00172.13 KUM57598.1 - 1.7e-09 37.4 8.2 3e-09 36.6 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep_2 PF14602.1 KUM57598.1 - 7.1e-06 25.4 7.7 0.00016 21.1 0.9 3.6 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase CRM1_C PF08767.6 KUM57599.1 - 4.3e-101 338.0 1.6 4.3e-101 338.0 1.1 3.0 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 KUM57599.1 - 7.7e-44 149.1 10.4 2.9e-43 147.3 3.2 4.1 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 KUM57599.1 - 8e-12 44.9 0.1 3.2e-11 42.9 0.1 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.3 KUM57599.1 - 0.0075 16.2 0.6 0.13 12.1 0.0 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) ALAD PF00490.16 KUM57600.1 - 7.5e-119 396.4 0.0 8.8e-119 396.1 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase OapA_N PF08525.6 KUM57600.1 - 0.17 11.6 0.8 2.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Opacity-associated protein A N-terminal motif Shugoshin_N PF07558.6 KUM57602.1 - 2.1e-16 59.3 5.1 2.1e-16 59.3 3.5 2.2 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 KUM57602.1 - 1.6e-10 40.2 4.3 1.6e-10 40.2 3.0 2.6 2 0 0 2 2 2 1 Shugoshin C terminus bZIP_1 PF00170.16 KUM57602.1 - 0.046 13.6 2.9 0.064 13.2 0.6 2.4 2 0 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.10 KUM57602.1 - 6.9 6.5 8.2 0.12 12.1 0.3 2.2 2 0 0 2 2 2 0 Basic region leucine zipper DASH_Dad2 PF08654.5 KUM57603.1 - 2.5e-31 107.7 0.1 3.1e-31 107.4 0.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 Dapper PF15268.1 KUM57603.1 - 0.0098 14.7 0.3 0.012 14.4 0.2 1.1 1 0 0 1 1 1 1 Dapper Seryl_tRNA_N PF02403.17 KUM57603.1 - 0.015 15.3 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain HAUS2 PF15003.1 KUM57603.1 - 0.062 12.3 0.0 0.082 11.9 0.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 FlxA PF14282.1 KUM57603.1 - 0.099 12.5 2.3 0.18 11.7 1.6 1.4 1 0 0 1 1 1 0 FlxA-like protein DUF4094 PF13334.1 KUM57603.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DAO PF01266.19 KUM57605.1 - 2e-50 171.6 0.0 2.7e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KUM57605.1 - 1.8e-08 33.6 0.8 4.9e-08 32.2 0.6 1.6 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KUM57605.1 - 3e-06 26.5 0.1 4e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KUM57605.1 - 6.1e-05 22.9 0.1 0.00052 19.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM57605.1 - 0.0014 18.6 0.1 0.0056 16.6 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 KUM57605.1 - 0.0094 15.6 0.2 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 KUM57605.1 - 0.0098 16.2 0.3 0.042 14.2 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KUM57605.1 - 0.016 13.6 0.2 0.028 12.8 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 KUM57605.1 - 0.024 13.7 0.0 0.059 12.4 0.0 1.6 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 KUM57605.1 - 0.029 13.2 0.0 0.095 11.5 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 KUM57605.1 - 0.03 13.3 0.0 0.074 12.0 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 KUM57605.1 - 0.11 11.3 0.3 0.5 9.1 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A GDI PF00996.13 KUM57605.1 - 0.11 10.7 0.3 0.53 8.5 0.0 1.9 2 0 0 2 2 2 0 GDP dissociation inhibitor Ecl1 PF12855.2 KUM57606.1 - 7.8e-08 31.4 0.8 1.8e-07 30.3 0.6 1.7 1 1 0 1 1 1 1 Life-span regulatory factor S100PBPR PF15427.1 KUM57606.1 - 0.037 13.1 3.1 0.041 12.9 2.1 1.0 1 0 0 1 1 1 0 S100P-binding protein DUF3829 PF12889.2 KUM57606.1 - 0.083 12.0 0.1 0.093 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Peptidase_C14 PF00656.17 KUM57606.1 - 0.087 12.4 2.4 0.11 12.1 1.7 1.0 1 0 0 1 1 1 0 Caspase domain p450 PF00067.17 KUM57607.1 - 1.6e-72 244.4 0.0 1.9e-72 244.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CRM1_C PF08767.6 KUM57608.1 - 2.2e-23 82.6 0.4 2.6e-23 82.4 0.3 1.0 1 0 0 1 1 1 1 CRM1 C terminal Aa_trans PF01490.13 KUM57610.1 - 1.8e-32 112.3 16.2 2.2e-32 112.0 11.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KUM57610.1 - 0.71 8.6 18.5 0.036 12.8 8.8 1.6 2 0 0 2 2 2 0 Tryptophan/tyrosine permease family DUF3632 PF12311.3 KUM57611.1 - 9.1e-39 133.1 0.0 1.2e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) HK97-gp10_like PF04883.7 KUM57611.1 - 0.078 13.9 0.1 0.19 12.6 0.1 1.6 1 0 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component Bradykinin PF06753.7 KUM57611.1 - 0.14 11.7 0.6 0.3 10.6 0.4 1.5 1 0 0 1 1 1 0 Bradykinin PLAC8 PF04749.12 KUM57612.1 - 1.1e-22 80.5 14.3 1.7e-22 79.9 9.9 1.3 1 0 0 1 1 1 1 PLAC8 family DUF853 PF05872.7 KUM57612.1 - 8.1 4.6 7.2 11 4.1 5.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) ERCC4 PF02732.10 KUM57614.1 - 3e-24 85.3 0.0 5.2e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain Glycos_transf_1 PF00534.15 KUM57615.1 - 1.1e-30 106.2 0.1 5.2e-29 100.8 0.1 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KUM57615.1 - 1.2e-10 41.4 0.0 1.5e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 KUM57615.1 - 4.2e-08 33.4 0.0 5.2e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KUM57615.1 - 9.5e-08 32.3 4.7 8.1e-07 29.3 3.3 2.4 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 KUM57615.1 - 0.0006 20.0 0.0 0.0015 18.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 MFS_1 PF07690.11 KUM57616.1 - 3.4e-22 78.6 15.1 3.4e-22 78.6 10.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.8 KUM57616.1 - 5.3e-08 32.4 1.4 1e-06 28.2 0.9 2.2 2 0 0 2 2 2 1 Nodulin-like Kinesin PF00225.18 KUM57617.1 - 5.3e-92 308.0 0.1 5.3e-92 308.0 0.1 3.0 2 1 0 2 2 2 1 Kinesin motor domain IPK PF03770.11 KUM57618.1 - 1.7e-58 197.5 0.0 2.8e-58 196.8 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.5 KUM57618.1 - 0.02 14.5 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 MFS_1 PF07690.11 KUM57619.1 - 3e-16 59.0 45.2 3e-16 59.0 31.3 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM57619.1 - 2.8e-10 39.0 10.2 2.8e-10 39.0 7.1 2.0 1 1 2 3 3 3 1 Fungal trichothecene efflux pump (TRI12) MR_MLE_C PF13378.1 KUM57619.1 - 0.21 11.5 0.8 0.87 9.5 0.1 2.2 2 0 0 2 2 2 0 Enolase C-terminal domain-like ATG2_CAD PF13329.1 KUM57620.1 - 1.3e-49 167.7 0.0 3e-49 166.5 0.0 1.7 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 KUM57620.1 - 2.1e-27 95.1 0.0 5.2e-27 93.8 0.0 1.8 1 0 0 1 1 1 1 ATG C terminal domain A_deaminase PF00962.17 KUM57621.1 - 1.7e-42 145.5 0.0 4.9e-42 144.0 0.0 1.7 2 1 0 2 2 2 1 Adenosine/AMP deaminase DUF2767 PF10965.3 KUM57621.1 - 0.17 11.7 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2767) Nucleos_tra2_C PF07662.8 KUM57623.1 - 1.2e-70 237.3 0.7 1.2e-70 237.3 0.5 2.4 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 KUM57623.1 - 2.1e-22 79.2 5.5 2.1e-22 79.2 3.8 2.8 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus L27 PF02828.11 KUM57624.1 - 0.033 13.8 0.4 0.18 11.5 0.1 2.4 2 0 0 2 2 2 0 L27 domain Amino_oxidase PF01593.19 KUM57626.1 - 4.4e-68 230.3 0.3 7.3e-68 229.6 0.2 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KUM57626.1 - 3.4e-10 39.7 0.1 1.1e-09 38.1 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KUM57626.1 - 3.2e-08 33.8 1.0 0.00011 22.3 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KUM57626.1 - 7.3e-06 25.1 1.6 0.00015 20.7 1.1 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KUM57626.1 - 1.8e-05 24.0 0.4 0.0081 15.2 0.1 2.7 3 0 0 3 3 3 2 FAD binding domain Pyr_redox PF00070.22 KUM57626.1 - 0.00012 22.4 1.3 0.089 13.2 0.1 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KUM57626.1 - 0.0013 18.6 0.1 0.0085 15.9 0.0 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KUM57626.1 - 0.0018 17.2 0.1 0.0065 15.3 0.0 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 KUM57626.1 - 0.0025 16.9 0.6 0.045 12.8 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KUM57626.1 - 0.0065 14.9 0.2 0.55 8.6 0.1 2.6 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.16 KUM57626.1 - 0.016 14.7 0.5 0.033 13.7 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 KUM57626.1 - 0.017 14.0 1.1 0.018 13.8 0.1 1.5 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.15 KUM57626.1 - 0.045 13.8 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 KUM57626.1 - 0.06 13.0 0.0 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.12 KUM57626.1 - 0.074 12.1 0.1 0.19 10.8 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Dickkopf_N PF04706.7 KUM57628.1 - 0.013 15.6 3.4 0.019 15.0 2.4 1.3 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Toxin_19 PF08088.7 KUM57628.1 - 0.021 14.7 4.9 0.027 14.3 3.4 1.2 1 0 0 1 1 1 0 Conotoxin I-superfamily Toxin_21 PF08091.6 KUM57628.1 - 0.14 11.8 9.9 0.27 10.9 6.9 1.4 1 0 0 1 1 1 0 Spider insecticidal peptide Conotoxin PF02950.12 KUM57628.1 - 0.24 12.2 10.4 3.5 8.4 7.2 2.1 1 1 0 1 1 1 0 Conotoxin Toxin_18 PF08087.6 KUM57628.1 - 1.5 8.6 10.4 11 5.8 7.3 2.2 1 1 0 1 1 1 0 Conotoxin O-superfamily Glyco_hydro_43 PF04616.9 KUM57629.1 - 1.3e-32 113.0 8.9 1.7e-32 112.6 6.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 SprB PF13573.1 KUM57629.1 - 0.15 11.7 1.5 1.4 8.6 0.1 2.5 2 0 0 2 2 2 0 SprB repeat DUF3534 PF12053.3 KUM57630.1 - 0.14 12.0 0.8 0.35 10.7 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3534) Pkinase PF00069.20 KUM57631.1 - 1.1e-69 234.5 0.0 1.8e-69 233.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM57631.1 - 6e-44 150.0 0.0 1e-43 149.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KUM57631.1 - 6.1e-21 74.6 1.6 1.1e-20 73.7 0.0 2.4 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 KUM57631.1 - 1.5e-06 27.4 0.0 2.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KUM57631.1 - 0.021 14.5 2.3 0.42 10.3 0.1 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family DSHCT PF08148.7 KUM57631.1 - 0.088 12.0 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 DSHCT (NUC185) domain VHS PF00790.14 KUM57632.1 - 5.6e-35 120.0 0.6 9.9e-35 119.2 0.4 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 KUM57632.1 - 3.7e-16 58.2 0.0 8.9e-16 57.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KUM57632.1 - 2e-15 56.1 0.1 3.7e-15 55.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KUM57632.1 - 1.5e-14 53.1 0.0 3e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain F-box PF00646.28 KUM57633.1 - 0.047 13.3 0.3 0.12 12.0 0.2 1.6 1 0 0 1 1 1 0 F-box domain GATase PF00117.23 KUM57635.1 - 0.0024 17.3 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I DUF2321 PF10083.4 KUM57635.1 - 0.17 11.4 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Fungal_trans PF04082.13 KUM57636.1 - 8.1e-15 54.3 0.6 2.1e-14 53.0 0.4 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain UCH_1 PF13423.1 KUM57637.1 - 4.1e-67 226.7 0.3 5.2e-67 226.3 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 KUM57637.1 - 1.1e-21 77.8 0.0 3.2e-21 76.3 0.0 1.8 2 0 0 2 2 2 1 Exonuclease UCH PF00443.24 KUM57637.1 - 1.5e-06 27.5 0.0 2.2e-05 23.7 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CcmH PF03918.9 KUM57637.1 - 0.17 10.9 0.2 0.31 10.0 0.1 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein Tub_2 PF04525.7 KUM57638.1 - 2.1e-07 30.5 0.0 3.7e-07 29.7 0.0 1.4 1 1 0 1 1 1 1 Tubby C 2 AA_permease_2 PF13520.1 KUM57639.1 - 1.5e-42 145.6 50.9 1.8e-42 145.4 35.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM57639.1 - 2.3e-18 65.7 43.8 3.1e-18 65.3 30.4 1.1 1 0 0 1 1 1 1 Amino acid permease Aldose_epim PF01263.15 KUM57640.1 - 1.6e-38 132.5 0.1 2e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase LBP_BPI_CETP_C PF02886.12 KUM57640.1 - 0.12 11.5 0.1 0.19 10.8 0.1 1.3 1 0 0 1 1 1 0 LBP / BPI / CETP family, C-terminal domain CARDB PF07705.6 KUM57640.1 - 0.15 12.1 0.1 0.32 11.0 0.1 1.5 1 0 0 1 1 1 0 CARDB MFS_1 PF07690.11 KUM57641.1 - 7.5e-29 100.5 20.8 1.4e-28 99.6 14.4 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily TPR_4 PF07721.9 KUM57642.1 - 0.045 14.1 0.1 5.7 7.6 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Bac_thur_toxin PF01338.13 KUM57645.1 - 0.027 13.6 0.2 0.046 12.9 0.1 1.3 1 0 0 1 1 1 0 Bacillus thuringiensis toxin EFP PF01132.15 KUM57645.1 - 0.11 12.2 0.6 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 Elongation factor P (EF-P) OB domain Glyco_hydro_3 PF00933.16 KUM57646.1 - 1.4e-84 283.6 0.0 2e-84 283.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KUM57646.1 - 4.9e-66 222.5 0.0 1.6e-65 220.7 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KUM57646.1 - 1.2e-22 79.5 1.5 3.4e-22 78.1 0.6 2.1 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 KUM57646.1 - 7.6e-16 58.0 0.1 1.7e-15 56.9 0.1 1.6 1 0 0 1 1 1 1 PA14 domain SNF PF00209.13 KUM57648.1 - 1.2e-74 251.6 30.4 1.2e-74 251.6 21.1 2.3 2 1 0 2 2 2 1 Sodium:neurotransmitter symporter family DUF2895 PF11444.3 KUM57648.1 - 0.048 12.8 0.0 1.9 7.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2895) DUF3810 PF12725.2 KUM57648.1 - 0.27 10.1 0.7 0.45 9.3 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) PSCyt3 PF07627.6 KUM57649.1 - 0.027 14.3 0.5 0.042 13.6 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) PMP22_Claudin PF00822.15 KUM57652.1 - 0.00015 21.4 5.4 0.00023 20.8 3.7 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family ABC2_membrane PF01061.19 KUM57652.1 - 0.00025 20.2 3.1 0.00025 20.2 2.1 1.9 1 1 1 2 2 2 1 ABC-2 type transporter Bac_rhodopsin PF01036.13 KUM57652.1 - 0.065 12.5 11.0 0.11 11.7 7.6 1.3 1 1 0 1 1 1 0 Bacteriorhodopsin-like protein MRAP PF15183.1 KUM57652.1 - 0.13 11.9 4.6 0.23 11.1 0.2 2.3 1 1 1 2 2 2 0 Melanocortin-2 receptor accessory protein family VPEP PF07589.6 KUM57652.1 - 0.22 11.4 1.0 0.4 10.6 0.2 1.9 2 0 0 2 2 2 0 PEP-CTERM motif Cytochrom_B_N PF00033.14 KUM57652.1 - 0.28 10.5 9.2 0.043 13.1 0.2 2.2 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB DUF1385 PF07136.6 KUM57652.1 - 4.3 6.3 6.7 0.98 8.4 0.5 2.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1385) DUF1129 PF06570.6 KUM57652.1 - 7 5.8 10.2 7.5 5.8 3.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Vma12 PF11712.3 KUM57652.1 - 9.1 5.9 6.8 1.6 8.4 2.0 1.6 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase FAD_binding_3 PF01494.14 KUM57653.1 - 8.5e-12 44.7 0.4 3.6e-11 42.7 0.3 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KUM57653.1 - 5.5e-05 22.2 0.8 0.00037 19.5 0.2 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KUM57653.1 - 0.00044 20.2 0.1 0.0018 18.2 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KUM57653.1 - 0.0019 18.2 0.1 0.23 11.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM57653.1 - 0.0028 17.4 0.3 0.041 13.6 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KUM57653.1 - 0.0049 16.7 0.0 0.0096 15.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KUM57653.1 - 0.017 15.4 0.0 0.077 13.4 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KUM57653.1 - 0.028 12.9 0.1 0.056 11.9 0.1 1.5 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 KUM57653.1 - 0.037 12.9 0.1 0.21 10.4 0.0 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 KUM57653.1 - 0.045 12.6 0.2 0.082 11.7 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KUM57653.1 - 0.069 12.2 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Thi4 family MFS_1 PF07690.11 KUM57654.1 - 6.6e-27 94.1 34.3 3.1e-20 72.2 8.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM57654.1 - 7.1e-16 57.8 24.2 4.3e-15 55.2 16.8 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter DIOX_N PF14226.1 KUM57655.1 - 3e-28 98.6 0.0 5.8e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KUM57655.1 - 2e-24 85.7 0.0 4.9e-24 84.4 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily APH PF01636.18 KUM57656.1 - 9.2e-09 35.3 0.0 0.0044 16.7 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Oxidored_FMN PF00724.15 KUM57657.1 - 1.2e-87 294.1 0.0 1.5e-87 293.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.19 KUM57657.1 - 0.063 12.5 0.0 0.25 10.6 0.0 2.0 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Dus PF01207.12 KUM57657.1 - 0.084 11.6 0.0 1.4 7.6 0.0 2.1 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Fungal_trans PF04082.13 KUM57658.1 - 1.8e-39 135.2 1.8 1.9e-39 135.1 0.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 KUM57658.1 - 5.7e-06 26.2 16.9 0.00061 19.9 2.3 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KUM57658.1 - 5.8e-05 23.1 19.8 0.007 16.6 1.6 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type FMN_dh PF01070.13 KUM57659.1 - 4.3e-92 308.7 0.0 2.8e-91 306.0 0.0 1.8 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KUM57659.1 - 8.4e-08 31.9 0.0 3.2e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KUM57659.1 - 1.7e-05 23.9 0.0 2.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KUM57659.1 - 0.00034 19.6 0.0 0.00078 18.4 0.0 1.5 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ATP11 PF06644.6 KUM57659.1 - 0.001 18.6 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 ATP11 protein His_biosynth PF00977.16 KUM57659.1 - 0.028 13.7 0.0 0.052 12.8 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein NMO PF03060.10 KUM57659.1 - 0.13 11.4 0.1 0.35 9.9 0.0 1.7 2 1 0 2 2 2 0 Nitronate monooxygenase Polysacc_deac_1 PF01522.16 KUM57660.1 - 2.5e-23 82.0 0.0 4.6e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase GST_N_2 PF13409.1 KUM57661.1 - 1.1e-10 41.3 0.0 2.6e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KUM57661.1 - 1.9e-08 34.0 0.0 3.2e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KUM57661.1 - 5.9e-08 32.6 0.0 9.4e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KUM57661.1 - 6e-08 32.8 0.0 1.2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KUM57661.1 - 1.4e-06 28.3 0.0 2.9e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain EPTP PF03736.12 KUM57661.1 - 0.087 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 EPTP domain Abhydrolase_5 PF12695.2 KUM57663.1 - 0.0016 18.2 0.0 0.003 17.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KUM57663.1 - 0.033 14.0 0.0 0.036 13.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family adh_short PF00106.20 KUM57664.1 - 0.0034 17.3 0.6 0.0047 16.8 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase OPT PF03169.10 KUM57665.1 - 6.3e-122 408.0 40.7 7.3e-122 407.8 28.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Ank_2 PF12796.2 KUM57666.1 - 7.2e-64 212.1 8.5 2.3e-20 72.7 0.7 4.1 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KUM57666.1 - 1.7e-56 185.2 22.1 4.1e-08 32.6 0.6 9.5 7 1 2 9 9 9 9 Ankyrin repeat Ank_4 PF13637.1 KUM57666.1 - 2.7e-52 174.2 19.8 1.2e-09 38.3 0.0 7.5 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM57666.1 - 8.6e-43 143.4 13.9 4.9e-08 32.9 0.5 9.2 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM57666.1 - 7.1e-36 118.6 9.9 0.0017 18.3 0.0 9.5 8 1 1 9 9 9 9 Ankyrin repeat Pedibin PF08182.6 KUM57666.1 - 0.23 10.9 2.0 3.1 7.3 0.0 3.3 3 0 0 3 3 3 0 Pedibin/Hym-346 family DUF3694 PF12473.3 KUM57668.1 - 0.021 14.5 0.0 0.023 14.3 0.0 1.1 1 0 0 1 1 1 0 Kinesin protein Zn_clus PF00172.13 KUM57670.1 - 2.8e-09 36.7 7.4 5.6e-09 35.7 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KUM57670.1 - 4.7e-05 22.4 0.0 7.4e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Catalase-rel PF06628.7 KUM57671.1 - 1.9e-11 43.6 0.0 2.7e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Catalase-related immune-responsive NmrA PF05368.8 KUM57673.1 - 4.2e-16 58.9 0.0 9.9e-16 57.6 0.0 1.5 1 1 1 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 KUM57673.1 - 6.2e-15 55.6 0.2 1.2e-14 54.7 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KUM57673.1 - 9.4e-05 22.7 0.0 0.0002 21.6 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 KUM57673.1 - 0.00018 21.0 0.0 0.00027 20.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GFO_IDH_MocA PF01408.17 KUM57673.1 - 0.0002 21.8 0.1 0.00036 21.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 KUM57673.1 - 0.00036 20.4 0.3 0.0012 18.7 0.0 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 KUM57673.1 - 0.0016 17.2 0.0 0.0024 16.6 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 KUM57673.1 - 0.0045 17.3 0.1 0.011 16.1 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 KUM57673.1 - 0.0086 15.0 0.0 0.014 14.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KUM57673.1 - 0.01 15.7 0.1 0.019 14.9 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase ApbA PF02558.11 KUM57673.1 - 0.037 13.4 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_4 PF07993.7 KUM57673.1 - 0.047 12.6 0.1 0.11 11.3 0.0 1.6 1 0 0 1 1 1 0 Male sterility protein RmlD_sub_bind PF04321.12 KUM57673.1 - 0.072 11.9 0.1 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain KR PF08659.5 KUM57673.1 - 0.096 12.3 0.1 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 KR domain NAD_binding_7 PF13241.1 KUM57673.1 - 0.1 12.8 0.1 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Lactamase_B PF00753.22 KUM57676.1 - 6.2e-11 42.3 0.8 2e-10 40.6 0.6 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KUM57676.1 - 7e-05 22.4 0.0 8.8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain E1-E2_ATPase PF00122.15 KUM57677.1 - 4.5e-69 232.0 0.4 4.5e-69 232.0 0.3 2.9 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 KUM57677.1 - 1.7e-23 84.1 0.0 6e-23 82.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KUM57677.1 - 3.1e-13 50.3 0.0 7.7e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KUM57677.1 - 2e-10 39.9 0.1 7.8e-10 38.0 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KUM57677.1 - 0.0017 17.9 0.1 0.0034 16.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KUM57677.1 - 0.011 15.6 0.0 0.028 14.3 0.0 1.7 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit GNVR PF13807.1 KUM57677.1 - 0.073 12.8 0.0 0.24 11.1 0.0 1.9 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase DMA PF03474.9 KUM57677.1 - 0.087 12.6 0.1 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 DMRTA motif ABC1 PF03109.11 KUM57678.1 - 9.2e-21 74.0 0.2 5.8e-20 71.4 0.0 2.3 2 0 0 2 2 2 1 ABC1 family APH PF01636.18 KUM57678.1 - 0.037 13.7 0.2 0.26 11.0 0.1 2.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family LRR_4 PF12799.2 KUM57679.1 - 3.1e-10 39.4 0.6 0.00042 19.8 0.0 4.3 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KUM57679.1 - 3.8e-09 35.6 5.0 0.27 11.4 0.1 7.2 8 0 0 8 8 8 2 Leucine Rich repeat LRR_8 PF13855.1 KUM57679.1 - 7.1e-05 22.4 3.8 0.019 14.6 0.1 4.0 3 1 0 3 3 3 1 Leucine rich repeat LRR_7 PF13504.1 KUM57679.1 - 0.0028 17.5 1.4 41 5.0 0.0 5.4 5 0 0 5 5 5 0 Leucine rich repeat LRR_1 PF00560.28 KUM57679.1 - 0.0032 17.2 8.9 1.4 9.2 0.1 5.8 8 0 0 8 8 8 1 Leucine Rich Repeat SDA1 PF05285.7 KUM57679.1 - 0.42 9.8 20.0 0.63 9.2 13.9 1.3 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.7 KUM57679.1 - 1.1 7.5 23.8 1.6 7.0 16.5 1.1 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.7 KUM57679.1 - 1.4 6.7 22.3 2.1 6.1 15.5 1.2 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 KUM57679.1 - 5.6 6.2 16.0 8.8 5.6 11.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Daxx PF03344.10 KUM57679.1 - 9.6 4.5 22.1 13 4.0 15.3 1.1 1 0 0 1 1 1 0 Daxx Family TFIIS_M PF07500.9 KUM57680.1 - 3.1e-26 91.6 0.2 7.5e-26 90.4 0.0 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 KUM57680.1 - 1.2e-18 66.4 4.7 2.4e-18 65.4 3.2 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 KUM57680.1 - 5.3e-13 48.2 0.4 1.3e-12 47.0 0.3 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.3 KUM57680.1 - 0.0079 15.5 1.1 0.02 14.2 0.8 1.7 1 1 0 1 1 1 1 Baculoviridae late expression factor 5 C-terminal domain Vasculin PF15337.1 KUM57680.1 - 0.46 10.9 3.2 1 9.8 0.2 2.6 2 1 1 3 3 3 0 Vascular protein family Vasculin-like 1 Alg6_Alg8 PF03155.10 KUM57681.1 - 9e-132 440.2 16.0 1.9e-83 280.9 4.8 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family COX17 PF05051.8 KUM57682.1 - 4e-21 74.7 6.7 8e-21 73.8 4.7 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 KUM57682.1 - 0.012 15.3 3.2 0.4 10.4 0.1 3.0 2 1 1 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like RRM_1 PF00076.17 KUM57684.1 - 4.7e-46 154.2 0.0 8.5e-22 76.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM57684.1 - 1e-35 121.4 0.0 5.3e-17 61.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM57684.1 - 1.4e-18 66.4 0.0 3.9e-09 36.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MRP-S33 PF08293.6 KUM57686.1 - 6.9e-36 122.1 0.1 8.5e-36 121.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 DUF382 PF04037.8 KUM57687.1 - 1.5e-62 209.1 1.1 3.3e-62 208.0 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 KUM57687.1 - 2.1e-21 75.0 4.7 6.1e-21 73.5 3.3 1.9 1 0 0 1 1 1 1 PSP ER_lumen_recept PF00810.13 KUM57688.1 - 1.4e-45 155.4 5.7 2e-45 154.8 3.9 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KUM57688.1 - 0.00077 18.9 5.6 0.3 10.6 0.1 2.9 3 0 0 3 3 3 2 PQ loop repeat XRCC4 PF06632.7 KUM57691.1 - 0.027 13.3 16.7 0.21 10.3 11.6 2.0 1 1 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Ribosomal_L38e PF01781.13 KUM57691.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal L38e protein family PBP_sp32 PF07222.7 KUM57691.1 - 1.5 7.9 4.3 2.2 7.4 3.0 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 NOA36 PF06524.7 KUM57691.1 - 7.8 5.6 6.7 12 5.0 4.7 1.3 1 0 0 1 1 1 0 NOA36 protein PUF PF00806.14 KUM57695.1 - 7.1e-34 113.3 3.4 3e-05 23.2 0.0 8.9 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat TPT PF03151.11 KUM57697.1 - 3.5e-34 117.6 4.1 3.5e-34 117.6 2.9 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KUM57697.1 - 3e-05 23.0 17.2 0.00031 19.7 11.9 2.1 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KUM57697.1 - 0.00083 19.3 6.5 0.00083 19.3 4.5 3.1 4 1 0 4 4 4 2 EamA-like transporter family Ribonuclease_3 PF00636.21 KUM57698.1 - 1.5e-16 60.8 0.0 5.4e-16 59.0 0.0 2.0 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KUM57698.1 - 3.9e-13 49.4 0.0 7.9e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 KUM57698.1 - 0.015 15.8 0.2 0.049 14.2 0.0 1.9 2 0 0 2 2 2 0 Double-stranded RNA binding motif p450 PF00067.17 KUM57700.1 - 7.8e-28 97.2 0.0 1.2e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF1399 PF07173.7 KUM57701.1 - 2.4e-21 76.4 1.4 7.6e-17 61.8 0.1 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1399) Fungal_trans PF04082.13 KUM57702.1 - 3e-13 49.2 2.1 3.5e-13 49.0 0.6 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM57702.1 - 1e-05 25.3 9.8 1e-05 25.3 6.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 KUM57703.1 - 0.025 14.9 1.0 0.073 13.4 0.7 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KUM57703.1 - 0.2 12.0 2.5 0.52 10.7 1.7 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type Pkinase PF00069.20 KUM57704.1 - 6.1e-73 245.1 0.0 8e-73 244.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM57704.1 - 4.4e-36 124.2 0.0 1.1e-35 122.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KUM57704.1 - 0.0048 16.6 0.0 0.54 9.9 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KUM57704.1 - 0.091 11.8 0.0 0.19 10.7 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KUM57704.1 - 0.2 10.6 3.2 1.5 7.6 0.0 3.1 4 0 0 4 4 4 0 Kinase-like MFS_1 PF07690.11 KUM57705.1 - 4.7e-29 101.1 40.3 1.6e-18 66.5 19.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM57705.1 - 5.1e-21 74.7 20.9 8.3e-21 74.0 14.5 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MMS22L_N PF14910.1 KUM57705.1 - 0.14 10.3 0.0 0.22 9.7 0.0 1.1 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, N-terminal AurF PF11583.3 KUM57706.1 - 0.047 12.6 0.2 0.063 12.1 0.2 1.1 1 0 0 1 1 1 0 P-aminobenzoate N-oxygenase AurF Peptidase_S10 PF00450.17 KUM57708.1 - 1.5e-90 304.3 0.0 2e-90 303.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Pyr_redox_2 PF07992.9 KUM57709.1 - 1.6e-06 28.1 0.0 1.5e-05 24.9 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM57709.1 - 0.0042 16.8 0.0 0.011 15.5 0.0 1.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 KUM57709.1 - 0.014 14.2 0.2 0.023 13.6 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KUM57709.1 - 0.015 15.3 0.1 0.03 14.3 0.1 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KUM57709.1 - 0.18 10.7 0.0 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Lactamase_B PF00753.22 KUM57710.1 - 4.4e-18 65.6 2.6 2.2e-17 63.3 1.8 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KUM57710.1 - 0.00072 19.1 0.3 0.0013 18.3 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Glyco_hydro_6 PF01341.12 KUM57711.1 - 7e-110 367.1 3.5 8.4e-110 366.8 2.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Ubie_methyltran PF01209.13 KUM57711.1 - 0.16 11.0 0.0 0.33 10.0 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Amino_oxidase PF01593.19 KUM57713.1 - 1.2e-49 169.6 0.5 5.7e-49 167.3 0.4 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Ribonuc_L-PSP PF01042.16 KUM57713.1 - 2.6e-14 53.0 0.0 4.6e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAD_binding_8 PF13450.1 KUM57713.1 - 2e-13 50.1 0.7 4.9e-13 48.9 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KUM57713.1 - 2e-09 36.8 0.9 5.1e-09 35.4 0.0 2.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KUM57713.1 - 2.6e-09 36.4 1.9 4e-09 35.8 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KUM57713.1 - 7.5e-07 29.2 0.2 1.1e-05 25.3 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KUM57713.1 - 1.9e-06 27.2 0.2 2.6e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KUM57713.1 - 2.1e-06 26.9 0.7 0.00012 21.1 0.4 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 KUM57713.1 - 2.1e-06 27.0 1.1 3.7e-06 26.2 0.8 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KUM57713.1 - 6.7e-06 24.8 0.7 4.9e-05 21.9 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 KUM57713.1 - 1.1e-05 25.6 1.0 5.3e-05 23.3 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KUM57713.1 - 3.4e-05 23.0 0.3 5.8e-05 22.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 KUM57713.1 - 0.0016 17.9 1.4 0.13 11.7 0.2 2.4 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 KUM57713.1 - 0.0019 17.1 2.0 0.004 16.0 1.4 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 KUM57713.1 - 0.052 13.9 1.0 0.089 13.2 0.2 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF2784 PF10861.3 KUM57713.1 - 0.057 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of Unknown function (DUF2784) Abhydrolase_5 PF12695.2 KUM57714.1 - 3.2e-06 26.9 0.0 5.7e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KUM57714.1 - 4.4e-06 26.7 0.8 6.4e-06 26.2 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KUM57714.1 - 0.00065 19.3 0.2 0.017 14.6 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2974 PF11187.3 KUM57714.1 - 0.012 14.9 0.1 0.045 13.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) HMG-CoA_red PF00368.13 KUM57715.1 - 6.5e-151 502.2 2.7 8.1e-151 501.9 1.9 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.3 KUM57715.1 - 7.7e-15 54.6 3.5 6.7e-14 51.6 2.4 2.2 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KUM57715.1 - 1.2e-09 36.6 0.8 1.2e-09 36.6 0.6 1.4 2 0 0 2 2 2 1 Patched family CK_II_beta PF01214.13 KUM57716.1 - 3.5e-72 241.7 0.1 4.9e-72 241.3 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Corona_M PF01635.13 KUM57716.1 - 5.4 5.8 5.9 9.7 5.0 4.1 1.3 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein JAB PF01398.16 KUM57718.1 - 3.1e-09 36.5 0.2 3.2e-08 33.2 0.1 2.2 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Sec34 PF04136.10 KUM57718.1 - 0.076 12.7 0.7 0.16 11.6 0.5 1.5 1 0 0 1 1 1 0 Sec34-like family Phage_XkdX PF09693.5 KUM57718.1 - 0.077 12.5 0.6 0.16 11.4 0.1 1.8 2 0 0 2 2 2 0 Phage uncharacterised protein (Phage_XkdX) Mito_carr PF00153.22 KUM57721.1 - 4.1e-42 141.8 2.5 3.3e-16 58.7 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein adh_short PF00106.20 KUM57722.1 - 3.5e-12 46.5 0.1 5.1e-12 46.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM57722.1 - 8.3e-07 28.8 0.4 1.2e-06 28.2 0.3 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KUM57722.1 - 4.4e-05 22.5 0.0 0.0018 17.2 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 KUM57722.1 - 0.017 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 KUM57722.1 - 0.024 14.7 0.1 0.042 13.9 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TPP_enzyme_C PF02775.16 KUM57722.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fungal_trans_2 PF11951.3 KUM57723.1 - 0.0023 16.6 0.0 0.0035 16.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SGL PF08450.7 KUM57724.1 - 1.2e-07 31.3 0.1 0.045 13.1 0.0 3.1 2 1 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Oxidored_FMN PF00724.15 KUM57725.1 - 4.9e-44 150.7 0.0 6.4e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Polysacc_deac_2 PF04748.8 KUM57725.1 - 0.079 11.9 0.1 0.19 10.6 0.0 1.6 2 0 0 2 2 2 0 Divergent polysaccharide deacetylase Cupin_2 PF07883.6 KUM57726.1 - 0.00053 19.4 0.0 0.00088 18.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain BNR_2 PF13088.1 KUM57727.1 - 1.3e-13 50.8 0.7 7.8e-09 35.2 0.3 3.2 1 1 2 3 3 3 3 BNR repeat-like domain BNR PF02012.15 KUM57727.1 - 5.9e-07 28.3 17.0 0.13 12.1 0.3 5.8 6 0 0 6 6 6 4 BNR/Asp-box repeat DUF2414 PF10309.4 KUM57727.1 - 0.08 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) Pyr_redox PF00070.22 KUM57728.1 - 1.3e-13 51.1 0.1 1.3e-10 41.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KUM57728.1 - 9.3e-13 48.5 0.0 0.0018 18.2 0.0 4.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KUM57728.1 - 5.6e-09 35.3 0.1 0.021 13.7 0.0 3.5 3 1 0 4 4 4 3 FAD dependent oxidoreductase K_oxygenase PF13434.1 KUM57728.1 - 2.4e-07 29.9 0.1 7.6e-07 28.3 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KUM57728.1 - 2.8e-07 30.8 0.4 0.004 17.2 0.0 3.2 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KUM57728.1 - 8.9e-07 29.1 0.0 5e-05 23.4 0.0 2.6 3 0 0 3 3 3 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 KUM57728.1 - 2.5e-05 24.1 0.0 0.054 13.5 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KUM57728.1 - 4e-05 23.4 0.6 0.95 9.2 0.0 3.9 3 1 1 4 4 4 2 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KUM57728.1 - 0.00024 19.8 0.1 0.076 11.6 0.0 2.4 2 1 0 2 2 2 2 Tryptophan halogenase TrkA_N PF02254.13 KUM57728.1 - 0.00025 21.0 0.4 0.11 12.4 0.0 3.6 4 0 0 4 4 4 1 TrkA-N domain Lycopene_cycl PF05834.7 KUM57728.1 - 0.018 13.9 0.0 0.064 12.1 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.11 KUM57728.1 - 0.041 13.3 0.0 0.17 11.3 0.0 2.1 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Fungal_trans PF04082.13 KUM57729.1 - 5.5e-26 91.0 0.1 1.1e-25 90.0 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM57729.1 - 0.016 15.1 0.5 0.03 14.2 0.3 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CorA PF01544.13 KUM57730.1 - 2.4e-08 33.3 4.3 5.6e-08 32.1 3.0 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein PSD3 PF07626.6 KUM57730.1 - 0.067 13.2 1.7 0.11 12.5 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1587) Glyco_hydro_72 PF03198.9 KUM57731.1 - 2.6e-130 433.9 8.5 3.5e-130 433.5 5.9 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 KUM57731.1 - 4.1e-23 81.6 6.5 4.1e-23 81.6 4.5 2.3 2 0 0 2 2 2 1 X8 domain TA0956 PF11513.3 KUM57731.1 - 0.089 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Thermoplasma acidophilum protein TA0956 DUF2406 PF10295.4 KUM57733.1 - 4.2e-20 72.0 1.0 6.1e-20 71.4 0.7 1.4 1 1 0 1 1 1 1 Uncharacterised protein (DUF2406) CoA_transf_3 PF02515.12 KUM57734.1 - 9.3e-62 207.6 0.0 1.3e-61 207.1 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III p450 PF00067.17 KUM57735.1 - 2.9e-51 174.4 0.0 4e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 KUM57736.1 - 6.2e-08 32.4 10.6 9.4e-08 31.8 7.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KUM57736.1 - 8.8e-07 27.8 0.0 1.2e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3176 PF11374.3 KUM57737.1 - 9.1e-42 141.4 0.8 1.7e-41 140.5 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) p450 PF00067.17 KUM57739.1 - 1.6e-68 231.3 0.0 2e-68 231.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_25 PF01755.12 KUM57740.1 - 3.7e-07 30.0 0.0 0.00052 19.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) UCR_Fe-S_N PF10399.4 KUM57740.1 - 0.14 11.3 0.9 0.58 9.3 0.0 2.2 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Sugar_tr PF00083.19 KUM57741.1 - 4.7e-88 295.7 25.4 5.7e-88 295.4 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM57741.1 - 3.4e-24 85.2 36.6 3.4e-24 85.2 25.3 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 KUM57741.1 - 7.7e-05 21.0 3.9 7.7e-05 21.0 2.7 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.4 KUM57741.1 - 0.078 12.9 7.8 0.024 14.6 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) MFS_2 PF13347.1 KUM57741.1 - 6.5 5.0 39.3 0.0092 14.4 2.8 3.9 2 2 1 4 4 4 0 MFS/sugar transport protein MFS_1 PF07690.11 KUM57743.1 - 3.2e-45 154.3 52.6 8.8e-45 152.9 35.2 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily FAD_binding_3 PF01494.14 KUM57744.1 - 4.2e-20 72.1 0.5 1.1e-11 44.4 0.2 2.7 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KUM57744.1 - 2.2e-05 23.5 0.0 8.1e-05 21.6 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KUM57744.1 - 6.7e-05 21.9 0.0 0.00014 20.8 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KUM57744.1 - 9.6e-05 22.3 0.1 0.0003 20.7 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain PALP PF00291.20 KUM57744.1 - 0.0018 17.5 0.0 0.0031 16.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HI0933_like PF03486.9 KUM57744.1 - 0.0026 16.2 0.0 0.0038 15.7 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 KUM57744.1 - 0.0029 17.5 0.0 0.0044 16.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.7 KUM57744.1 - 0.003 16.9 0.0 0.0086 15.4 0.0 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain Lycopene_cycl PF05834.7 KUM57744.1 - 0.0034 16.3 1.3 0.0076 15.2 0.0 2.1 3 0 0 3 3 3 1 Lycopene cyclase protein TrkA_N PF02254.13 KUM57744.1 - 0.007 16.3 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Thi4 PF01946.12 KUM57744.1 - 0.0098 15.0 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 KUM57744.1 - 0.014 15.4 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 KUM57744.1 - 0.024 14.3 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus CPSase_L_chain PF00289.17 KUM57744.1 - 0.03 14.4 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Pyr_redox PF00070.22 KUM57744.1 - 0.057 13.8 0.0 0.42 11.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KUM57744.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KUM57744.1 - 0.16 12.0 0.1 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Response_reg PF00072.19 KUM57745.1 - 1.8e-23 82.6 1.2 6.1e-23 80.9 0.1 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 KUM57745.1 - 1.2e-22 79.7 0.0 2.2e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KUM57745.1 - 4.5e-11 42.5 1.5 5.9e-11 42.2 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 KUM57745.1 - 2.5e-05 24.3 0.0 6.5e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 KUM57745.1 - 0.00037 20.5 0.1 0.0013 18.7 0.0 2.0 1 1 1 2 2 2 1 PAS fold PAS_7 PF12860.2 KUM57745.1 - 0.00099 19.1 0.0 0.049 13.6 0.0 3.1 2 1 0 2 2 2 1 PAS fold HATPase_c_5 PF14501.1 KUM57745.1 - 0.25 11.0 2.1 0.88 9.3 0.0 2.7 3 0 0 3 3 3 0 GHKL domain FAD_binding_3 PF01494.14 KUM57747.1 - 1.9e-20 73.2 0.0 3.9e-20 72.2 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 KUM57747.1 - 2.6e-07 30.9 0.1 2.1e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KUM57747.1 - 2.7e-07 29.8 0.0 1.2e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KUM57747.1 - 0.00057 19.8 0.1 0.017 15.1 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 KUM57747.1 - 0.00067 19.1 0.0 0.0013 18.2 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 KUM57747.1 - 0.013 15.5 0.0 0.076 13.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Toxin_62 PF15540.1 KUM57747.1 - 0.091 12.8 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 Putative toxin 62 TrkA_N PF02254.13 KUM57747.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Hexapep PF00132.19 KUM57748.1 - 2.5e-08 33.0 4.9 0.00074 18.9 0.5 3.8 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KUM57748.1 - 6e-05 23.1 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 KUM57748.1 - 0.016 14.7 5.2 0.4 10.2 0.7 3.0 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase BetaGal_dom2 PF10435.4 KUM57750.1 - 2.5e-64 215.9 1.5 2.5e-64 215.9 1.0 1.8 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 KUM57750.1 - 5.2e-49 165.1 12.4 7.5e-26 90.5 2.7 2.9 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 KUM57750.1 - 1.6e-29 101.1 0.1 6e-28 96.0 0.0 2.4 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Glyco_hydro_35 PF01301.14 KUM57750.1 - 1.5e-16 60.6 0.2 1.5e-16 60.6 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 NmrA PF05368.8 KUM57751.1 - 1.9e-10 40.3 0.0 4.4e-10 39.2 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KUM57751.1 - 4e-06 26.9 0.1 8.5e-06 25.8 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KUM57751.1 - 0.032 14.5 0.1 0.07 13.4 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 KUM57751.1 - 0.093 12.3 0.2 3.3 7.3 0.1 2.4 2 1 0 3 3 3 0 KR domain Spt20 PF12090.3 KUM57752.1 - 2.5e-51 173.6 0.1 2.5e-51 173.6 0.0 4.3 4 1 0 4 4 4 1 Spt20 family zf-C2H2 PF00096.21 KUM57754.1 - 8.5e-08 32.1 12.4 0.00076 19.6 2.7 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KUM57754.1 - 1.5e-05 25.0 4.3 1.5e-05 25.0 3.0 3.8 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KUM57754.1 - 5.6e-05 23.1 10.6 0.0037 17.4 1.0 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger Glyco_hydro_35 PF01301.14 KUM57755.1 - 2.8e-54 184.6 0.0 3.4e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Cellulase PF00150.13 KUM57755.1 - 2.3e-06 27.0 0.3 3e-06 26.6 0.2 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AF1Q PF15017.1 KUM57755.1 - 0.042 13.7 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator Amidohydro_2 PF04909.9 KUM57755.1 - 0.068 12.7 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase MFS_1 PF07690.11 KUM57756.1 - 4.8e-35 120.9 26.9 6.5e-35 120.4 18.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1616 PF07760.6 KUM57756.1 - 0.0063 15.6 3.5 0.015 14.4 2.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1616) RskA PF10099.4 KUM57756.1 - 0.1 12.3 0.5 1 9.0 0.1 2.6 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Herpes_LMP2 PF07415.6 KUM57757.1 - 4.7 5.6 8.7 6.3 5.2 6.0 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Zn_clus PF00172.13 KUM57758.1 - 4.8e-10 39.1 10.0 1.1e-09 38.0 6.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KUM57758.1 - 0.00028 19.5 0.1 0.00041 19.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_12 PF08242.7 KUM57759.1 - 1e-14 54.8 0.0 5.5e-14 52.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM57759.1 - 5.3e-13 49.0 0.2 2.5e-12 46.7 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM57759.1 - 9.5e-11 42.0 0.0 3.6e-10 40.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM57759.1 - 1.2e-08 35.4 0.0 1e-07 32.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM57759.1 - 2.8e-07 30.8 0.0 7.2e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM57759.1 - 2.8e-07 30.2 0.0 1.1e-06 28.2 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KUM57759.1 - 7.6e-07 29.1 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KUM57759.1 - 1.6e-06 27.4 0.0 3.4e-06 26.3 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family DUF3419 PF11899.3 KUM57759.1 - 0.00043 19.1 0.0 0.00069 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) MTS PF05175.9 KUM57759.1 - 0.0012 18.2 0.0 0.0025 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.10 KUM57759.1 - 0.0012 18.5 0.0 0.33 10.5 0.0 2.4 2 0 0 2 2 2 2 Hypothetical methyltransferase Methyltransf_24 PF13578.1 KUM57759.1 - 0.0073 17.1 0.0 0.061 14.1 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KUM57759.1 - 0.012 14.5 0.0 0.35 9.7 0.0 2.1 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_16 PF10294.4 KUM57759.1 - 0.16 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PIG-S PF10510.4 KUM57760.1 - 1.5e-178 594.6 0.0 1.7e-178 594.4 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein HlyIII PF03006.15 KUM57761.1 - 2.8e-56 190.3 24.9 3.5e-56 190.1 17.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related SPC12 PF06645.8 KUM57761.1 - 0.0063 16.2 0.8 0.0063 16.2 0.5 2.5 2 0 0 2 2 2 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF373 PF04123.8 KUM57761.1 - 2 7.3 5.5 3.4 6.5 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF1517 PF07466.6 KUM57762.1 - 7.8 5.3 7.1 24 3.7 4.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1517) MaoC_dehydrat_N PF13452.1 KUM57763.1 - 0.0064 16.2 0.0 0.82 9.4 0.0 2.4 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase Aldo_ket_red PF00248.16 KUM57764.1 - 5.5e-51 173.0 0.0 6.1e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Polyketide_cyc PF03364.15 KUM57765.1 - 6.6e-23 81.1 0.0 2.3e-22 79.3 0.0 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Fungal_trans PF04082.13 KUM57766.1 - 7.8e-15 54.4 1.0 1.3e-14 53.7 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane PF01061.19 KUM57767.1 - 1.5e-35 122.3 21.3 2.8e-35 121.3 14.8 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KUM57767.1 - 5.3e-23 81.8 0.1 5.3e-23 81.8 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 KUM57767.1 - 8e-10 39.1 0.0 7.6e-09 35.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 KUM57767.1 - 8.8e-06 24.9 24.2 8.8e-06 24.9 16.8 1.8 1 1 1 2 2 2 1 ABC-2 family transporter protein hEGF PF12661.2 KUM57767.1 - 0.00012 21.9 22.1 0.034 14.2 1.8 4.0 3 0 0 3 3 3 2 Human growth factor-like EGF AAA_25 PF13481.1 KUM57767.1 - 0.0021 17.4 0.0 0.27 10.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KUM57767.1 - 0.012 14.8 0.0 0.023 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 KUM57767.1 - 0.034 13.6 0.2 0.075 12.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.14 KUM57767.1 - 0.035 13.3 0.0 0.8 8.8 0.0 2.4 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KUM57767.1 - 0.04 12.9 0.0 0.9 8.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 KUM57767.1 - 0.1 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KUM57767.1 - 0.16 12.3 0.1 0.36 11.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain EGF_2 PF07974.8 KUM57767.1 - 0.24 11.5 36.5 0.025 14.7 8.7 4.4 4 0 0 4 4 4 0 EGF-like domain Laminin_EGF PF00053.19 KUM57767.1 - 7.3 6.6 30.5 1.2 9.1 5.5 3.7 2 1 1 3 3 3 0 Laminin EGF-like (Domains III and V) AMP-binding PF00501.23 KUM57768.1 - 4.8e-65 219.5 0.0 6.6e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KUM57768.1 - 2e-07 31.8 0.0 3.7e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aminotran_1_2 PF00155.16 KUM57769.1 - 3.5e-45 154.5 0.0 4.2e-45 154.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KUM57769.1 - 1.4e-07 30.5 0.0 3e-07 29.5 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KUM57769.1 - 1.5e-07 30.8 0.0 2.5e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 KUM57769.1 - 1.5e-05 23.4 0.0 2.2e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KUM57769.1 - 0.0072 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.8 KUM57769.1 - 0.17 10.5 0.0 0.3 9.6 0.0 1.4 1 1 0 1 1 1 0 Allinase Sod_Fe_C PF02777.13 KUM57770.1 - 2e-13 50.1 0.5 8.1e-08 32.0 0.6 2.3 1 1 1 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KUM57770.1 - 0.027 14.7 0.1 0.045 14.0 0.1 1.4 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain FimP PF09766.4 KUM57771.1 - 3.6e-26 92.0 13.0 4.4e-26 91.7 9.0 1.1 1 0 0 1 1 1 1 Fms-interacting protein DUF4200 PF13863.1 KUM57771.1 - 0.0002 21.3 11.9 0.025 14.5 0.5 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) Cortex-I_coil PF09304.5 KUM57771.1 - 0.022 14.7 12.1 0.51 10.4 3.2 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil RNase_E_G PF10150.4 KUM57771.1 - 0.17 11.0 6.7 0.1 11.7 1.4 2.0 2 0 0 2 2 2 0 Ribonuclease E/G family DUF972 PF06156.8 KUM57771.1 - 1.6 9.1 8.1 7.8 6.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) MRP-S28 PF10213.4 KUM57771.1 - 2.1 8.4 6.0 0.37 10.8 0.6 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit protein DUF1003 PF06210.6 KUM57771.1 - 3.6 7.5 9.0 0.41 10.5 0.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1003) K-box PF01486.12 KUM57771.1 - 6.3 6.6 12.9 0.17 11.7 0.4 3.2 2 2 2 4 4 4 0 K-box region FAD_binding_3 PF01494.14 KUM57773.1 - 3.2e-08 33.0 0.0 4.2e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 KUM57773.1 - 0.0082 14.9 0.0 0.011 14.5 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase SnAC PF14619.1 KUM57773.1 - 0.14 12.2 0.0 0.65 10.2 0.0 2.1 3 0 0 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex TrkH PF02386.11 KUM57774.1 - 1.5e-105 352.7 6.6 1.8e-105 352.4 4.6 1.1 1 0 0 1 1 1 1 Cation transport protein Cupin_2 PF07883.6 KUM57775.1 - 3.1e-10 39.4 0.1 1.7e-08 33.8 0.0 2.7 3 0 0 3 3 3 1 Cupin domain Cupin_3 PF05899.7 KUM57775.1 - 0.017 14.4 0.0 4.3 6.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Cupin_1 PF00190.17 KUM57775.1 - 0.023 14.1 0.0 1.5 8.2 0.0 2.7 2 1 1 3 3 3 0 Cupin AraC_binding PF02311.14 KUM57775.1 - 0.073 12.7 0.0 0.29 10.8 0.0 2.0 2 0 0 2 2 2 0 AraC-like ligand binding domain Cupin_4 PF08007.7 KUM57775.1 - 0.11 11.6 0.1 0.11 11.6 0.1 1.5 2 0 0 2 2 2 0 Cupin superfamily protein Abhydrolase_3 PF07859.8 KUM57776.1 - 9.6e-13 48.1 0.0 8.7e-10 38.5 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KUM57776.1 - 6.6e-09 35.3 0.0 1.1e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KUM57776.1 - 9.8e-08 31.8 0.0 2e-07 30.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KUM57776.1 - 1.3e-07 30.6 0.1 6.2e-07 28.5 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.2 KUM57776.1 - 1e-06 28.8 0.0 1.5e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KUM57776.1 - 8.1e-05 21.6 0.0 0.00014 20.8 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme AXE1 PF05448.7 KUM57776.1 - 0.00019 20.0 0.0 0.065 11.7 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 KUM57776.1 - 0.00028 20.3 0.0 0.71 9.2 0.0 2.4 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Esterase PF00756.15 KUM57776.1 - 0.00087 18.7 0.1 0.015 14.7 0.0 2.1 1 1 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.13 KUM57776.1 - 0.035 13.5 0.0 0.23 10.8 0.0 2.1 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) MIF4G PF02854.14 KUM57778.1 - 5.2e-62 208.9 0.0 2.2e-33 115.4 0.0 3.4 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 KUM57778.1 - 3.1e-59 199.5 18.6 3.1e-59 199.5 12.9 2.7 3 0 0 3 3 3 1 Up-frameshift suppressor 2 SUN PF03856.8 KUM57781.1 - 6.3e-98 327.0 8.1 1.2e-97 326.1 5.6 1.4 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Mg_trans_NIPA PF05653.9 KUM57783.1 - 3.9e-13 49.0 8.4 1.6e-08 33.9 1.5 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 KUM57783.1 - 6.7e-06 26.1 0.5 6.7e-06 26.1 0.3 2.6 2 0 0 2 2 2 1 EamA-like transporter family YTH PF04146.10 KUM57783.1 - 0.2 11.2 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 YT521-B-like domain vATP-synt_E PF01991.13 KUM57784.1 - 5.6e-59 198.7 9.1 6.5e-59 198.5 6.3 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit WAPL PF07814.8 KUM57784.1 - 0.0029 16.3 1.6 0.0037 16.0 1.1 1.1 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin DUF4288 PF14119.1 KUM57784.1 - 0.1 12.7 6.9 7.6 6.7 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4288) SEN1_N PF12726.2 KUM57785.1 - 2.1e-229 763.3 0.4 2.7e-229 762.9 0.3 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 KUM57785.1 - 3.1e-69 233.1 0.8 3.1e-69 233.1 0.5 2.0 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 KUM57785.1 - 5e-63 212.1 0.0 9.4e-63 211.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KUM57785.1 - 3.5e-11 42.6 0.3 1.2e-10 40.9 0.2 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KUM57785.1 - 1e-08 34.9 0.1 0.00014 21.5 0.1 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 KUM57785.1 - 8.5e-07 28.7 0.2 0.033 13.7 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 KUM57785.1 - 9.3e-07 28.4 0.0 3.2e-05 23.3 0.0 2.4 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain zf-CCHC PF00098.18 KUM57785.1 - 0.00063 19.5 2.9 0.00063 19.5 2.0 3.3 3 0 0 3 3 3 2 Zinc knuckle DEAD PF00270.24 KUM57785.1 - 0.002 17.6 0.6 0.0099 15.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase T2SE PF00437.15 KUM57785.1 - 0.0044 15.9 0.0 0.0093 14.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.4 KUM57785.1 - 0.01 14.8 0.3 0.11 11.4 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) zf-CCHC_3 PF13917.1 KUM57785.1 - 0.022 14.5 22.5 0.13 11.9 0.3 4.1 2 1 2 4 4 4 0 Zinc knuckle MPP6 PF10175.4 KUM57785.1 - 0.023 15.0 0.4 0.066 13.5 0.2 1.7 1 0 0 1 1 1 0 M-phase phosphoprotein 6 AAA_25 PF13481.1 KUM57785.1 - 0.069 12.5 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KUM57785.1 - 0.078 13.1 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pyrid_oxidase_2 PF13883.1 KUM57786.1 - 8e-33 113.5 0.0 1.3e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase HAD PF12710.2 KUM57788.1 - 2.1e-13 50.8 0.1 4e-13 49.9 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KUM57788.1 - 9.7e-12 44.6 0.0 2.5e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 KUM57788.1 - 7.1e-11 41.5 0.2 2.3e-10 39.9 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KUM57788.1 - 2.4e-10 41.1 3.5 6.1e-09 36.5 2.4 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KUM57788.1 - 0.04 14.1 0.1 0.096 12.8 0.1 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KUM57788.1 - 0.041 13.4 0.5 0.1 12.1 0.3 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Transp_cyt_pur PF02133.10 KUM57789.1 - 1.8e-82 277.2 44.1 2.4e-81 273.5 30.6 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Cyclin PF08613.6 KUM57790.1 - 7.7e-14 52.3 0.0 1.9e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KUM57790.1 - 0.011 15.2 0.2 0.022 14.3 0.0 1.5 2 0 0 2 2 2 0 Cyclin, N-terminal domain SRF-TF PF00319.13 KUM57791.1 - 1.3e-23 81.9 0.2 1.9e-23 81.4 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.9 KUM57791.1 - 0.11 10.4 0.1 0.15 10.0 0.0 1.2 1 0 0 1 1 1 0 CDC45-like protein YbgS PF13985.1 KUM57791.1 - 0.18 11.7 1.1 0.34 10.8 0.7 1.5 1 0 0 1 1 1 0 YbgS-like protein Glyco_hydro_2_N PF02837.13 KUM57792.1 - 2.4e-05 23.9 0.0 8.2e-05 22.2 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF3798 PF12683.2 KUM57792.1 - 0.29 10.1 0.0 1.5 7.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3798) Iso_dh PF00180.15 KUM57793.1 - 1.3e-84 284.1 0.0 1.6e-84 283.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase WBS_methylT PF12589.3 KUM57794.1 - 9.2e-17 61.3 0.4 1.7e-16 60.4 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 KUM57794.1 - 4.2e-11 43.1 0.0 7.3e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM57794.1 - 4.6e-09 36.5 0.0 8.1e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM57794.1 - 2e-06 27.4 0.0 3e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM57794.1 - 1.7e-05 25.1 0.0 4.4e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM57794.1 - 2.5e-05 24.8 0.0 4.8e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KUM57794.1 - 5.3e-05 23.2 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM57794.1 - 0.0001 22.0 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KUM57794.1 - 0.0004 19.9 0.0 0.00068 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 KUM57794.1 - 0.0066 15.5 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KUM57794.1 - 0.11 11.5 0.0 1.2 8.1 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Erv26 PF04148.8 KUM57795.1 - 1.8e-91 305.2 0.1 2e-91 305.0 0.1 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DMRL_synthase PF00885.14 KUM57796.1 - 9.3e-45 151.8 0.0 3.3e-25 88.4 0.0 2.0 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase Proteasome PF00227.21 KUM57797.1 - 4.2e-46 156.6 0.2 9.4e-32 109.8 0.0 2.6 3 0 0 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.4 KUM57797.1 - 8.4e-12 44.1 0.9 1e-11 43.9 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Lar_restr_allev PF14354.1 KUM57798.1 - 0.0064 16.7 0.3 0.017 15.4 0.2 1.7 1 0 0 1 1 1 1 Restriction alleviation protein Lar DZR PF12773.2 KUM57798.1 - 0.031 14.0 0.9 0.088 12.6 0.6 1.7 1 0 0 1 1 1 0 Double zinc ribbon Ogr_Delta PF04606.7 KUM57798.1 - 0.072 12.7 2.7 2 8.1 0.2 2.5 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Cys_rich_CPXG PF14255.1 KUM57798.1 - 0.7 9.7 3.3 1.8 8.4 2.3 1.7 1 1 0 1 1 1 0 Cysteine-rich CPXCG zf-ISL3 PF14690.1 KUM57798.1 - 2.9 7.9 6.6 2.2 8.3 0.2 3.0 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_Tnp_IS1595 PF12760.2 KUM57798.1 - 3.3 7.5 5.4 37 4.2 3.9 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.1 KUM57798.1 - 4.1 6.7 8.3 1.3 8.3 2.6 2.4 2 1 1 3 3 3 0 zinc-ribbon domain UPF0547 PF10571.4 KUM57798.1 - 5.5 6.7 8.5 2.2 8.0 2.3 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Chlorosome_CsmC PF11098.3 KUM57799.1 - 0.019 14.6 0.3 0.024 14.3 0.2 1.3 1 1 0 1 1 1 0 Chlorosome envelope protein C DUF1059 PF06348.6 KUM57799.1 - 0.032 14.0 1.1 7 6.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) ABC_tran PF00005.22 KUM57802.1 - 5e-47 159.6 0.0 3.1e-26 92.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KUM57802.1 - 4.3e-31 108.3 34.9 5.7e-26 91.5 11.5 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KUM57802.1 - 2.3e-11 43.3 0.2 0.00014 21.2 0.0 3.3 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KUM57802.1 - 9.6e-09 35.6 0.8 0.009 16.0 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 KUM57802.1 - 4.6e-08 33.2 2.1 0.0052 16.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KUM57802.1 - 8.3e-08 31.6 0.2 0.0014 18.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KUM57802.1 - 8.3e-05 22.7 0.4 0.14 12.2 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KUM57802.1 - 0.00015 21.6 0.3 0.2 11.5 0.0 3.7 3 1 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 KUM57802.1 - 0.00022 21.1 0.1 0.024 14.5 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 KUM57802.1 - 0.00049 19.3 0.0 0.013 14.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 KUM57802.1 - 0.0016 17.9 2.2 0.035 13.5 0.0 2.7 2 1 0 2 2 2 1 AAA-like domain Miro PF08477.8 KUM57802.1 - 0.0049 17.3 0.0 4 7.9 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_25 PF13481.1 KUM57802.1 - 0.0074 15.7 0.3 0.5 9.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KUM57802.1 - 0.015 15.0 0.1 0.22 11.2 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 KUM57802.1 - 0.017 14.9 0.4 7.4 6.5 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 KUM57802.1 - 0.02 14.3 0.3 3.4 7.1 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 KUM57802.1 - 0.024 14.3 0.0 0.063 12.9 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase cobW PF02492.14 KUM57802.1 - 0.024 14.0 0.4 0.069 12.5 0.0 2.0 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 KUM57802.1 - 0.028 14.6 0.5 2.1 8.5 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 KUM57802.1 - 0.037 12.9 1.0 0.13 11.1 0.0 2.2 2 1 1 3 3 3 0 Type II/IV secretion system protein AAA_23 PF13476.1 KUM57802.1 - 0.063 13.6 0.1 0.063 13.6 0.1 2.8 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KUM57802.1 - 0.074 13.3 0.0 3.1 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KUM57802.1 - 0.099 11.7 0.0 0.5 9.4 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.18 KUM57802.1 - 0.1 12.3 1.6 0.34 10.7 0.0 2.3 2 1 0 2 2 2 0 Dynamin family AAA_17 PF13207.1 KUM57802.1 - 0.11 13.3 7.3 0.62 10.9 0.0 3.1 3 0 0 3 3 2 0 AAA domain DUF1427 PF07235.6 KUM57802.1 - 0.15 12.1 1.9 0.5 10.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1427) DUF87 PF01935.12 KUM57802.1 - 0.16 11.7 0.9 5.6 6.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 NTPase_1 PF03266.10 KUM57802.1 - 0.51 10.0 1.4 5.8 6.5 0.0 2.7 3 0 0 3 3 3 0 NTPase Aa_trans PF01490.13 KUM57803.1 - 5.7e-40 137.0 37.9 6.9e-40 136.7 26.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RhoGAP PF00620.22 KUM57804.1 - 1.5e-41 141.4 0.1 3.6e-41 140.2 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 KUM57804.1 - 5.5e-13 49.0 0.0 9.8e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KUM57804.1 - 2e-07 31.2 0.0 4.8e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 KUM57804.1 - 0.011 15.8 0.0 0.14 12.2 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain DUF3450 PF11932.3 KUM57804.1 - 0.013 14.8 0.7 0.023 13.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SIS PF01380.17 KUM57805.1 - 4.4e-55 184.8 0.0 5.7e-29 100.3 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 KUM57805.1 - 2.4e-28 98.8 0.0 3.9e-19 68.5 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KUM57805.1 - 2.1e-19 69.8 0.0 4.4e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KUM57805.1 - 1.4e-12 47.4 0.0 3.1e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 KUM57805.1 - 2.4e-08 33.0 0.2 5.2e-08 31.8 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Hemerythrin PF01814.18 KUM57806.1 - 9e-12 45.2 2.4 1.1e-11 45.0 1.7 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain SQS_PSY PF00494.14 KUM57807.1 - 1.1e-41 142.8 0.0 2.5e-41 141.7 0.0 1.5 2 0 0 2 2 2 1 Squalene/phytoene synthase Synaptobrevin PF00957.16 KUM57807.1 - 0.069 12.7 0.2 8 6.1 0.0 2.4 2 0 0 2 2 2 0 Synaptobrevin PDGLE PF13190.1 KUM57807.1 - 0.13 11.9 0.1 5.7 6.6 0.0 2.3 2 0 0 2 2 2 0 PDGLE domain DUF2951 PF11166.3 KUM57807.1 - 0.91 9.4 3.2 0.56 10.0 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2951) LMP PF04778.7 KUM57807.1 - 1.3 8.7 8.4 13 5.5 0.1 3.2 2 1 0 2 2 2 0 LMP repeated region TauD PF02668.11 KUM57808.1 - 3.2e-53 181.0 0.3 3.8e-53 180.7 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cellulase PF00150.13 KUM57809.1 - 4.3e-16 58.9 0.2 5.4e-16 58.6 0.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 KUM57809.1 - 0.0031 16.4 0.0 0.0097 14.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain RNA_bind PF08675.6 KUM57809.1 - 0.074 13.0 0.1 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 RNA binding domain Glyco_hydro_42 PF02449.10 KUM57809.1 - 0.09 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase Acetyltransf_1 PF00583.19 KUM57810.1 - 2.1e-13 50.0 0.1 3.6e-13 49.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KUM57810.1 - 1.9e-05 24.7 0.0 2.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KUM57810.1 - 3.9e-05 23.7 0.1 5e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KUM57810.1 - 0.0035 17.0 0.0 0.0059 16.3 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 KUM57810.1 - 0.0058 16.4 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 KUM57810.1 - 0.01 15.7 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KUM57810.1 - 0.16 11.8 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.1 KUM57811.1 - 4.5e-47 160.5 56.6 5.6e-47 160.2 39.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM57811.1 - 1.8e-27 95.8 50.1 2.4e-27 95.4 34.7 1.0 1 0 0 1 1 1 1 Amino acid permease GAPT PF11770.3 KUM57811.1 - 0.092 12.4 1.5 0.2 11.3 1.1 1.5 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) His_Phos_2 PF00328.17 KUM57812.1 - 8.8e-34 117.3 0.0 1.1e-33 117.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF2236 PF09995.4 KUM57813.1 - 1e-12 47.8 0.0 3.6e-12 46.0 0.0 1.8 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF1875 PF08961.5 KUM57814.1 - 0.29 10.4 4.5 0.72 9.1 0.2 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF1875) DnaJ-X PF14308.1 KUM57815.1 - 3.4e-72 242.0 5.3 3.4e-72 242.0 3.7 3.2 3 1 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 KUM57815.1 - 1.1e-25 89.0 0.3 4.9e-25 87.0 0.2 2.2 1 0 0 1 1 1 1 DnaJ domain MARVEL PF01284.18 KUM57816.1 - 6.6e-08 32.4 14.2 8.7e-08 32.1 9.8 1.2 1 0 0 1 1 1 1 Membrane-associating domain Xpo1 PF08389.7 KUM57816.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Exportin 1-like protein Na_Ca_ex PF01699.19 KUM57816.1 - 0.28 10.7 10.6 0.58 9.7 7.4 1.5 1 1 0 1 1 1 0 Sodium/calcium exchanger protein DUF420 PF04238.7 KUM57816.1 - 0.54 10.2 7.7 0.057 13.3 2.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF420) DUF3099 PF11298.3 KUM57816.1 - 3.5 7.4 12.8 0.73 9.6 3.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3099) AA_permease PF00324.16 KUM57817.1 - 6.4e-101 338.0 48.5 6.4e-101 338.0 33.6 2.8 2 1 0 2 2 2 1 Amino acid permease AA_permease_2 PF13520.1 KUM57817.1 - 2.8e-24 85.4 41.8 2.8e-24 85.4 29.0 2.1 2 0 0 2 2 2 1 Amino acid permease Peptidase_A4 PF01828.12 KUM57820.1 - 7.5e-81 270.1 7.0 8.8e-81 269.9 4.9 1.1 1 0 0 1 1 1 1 Peptidase A4 family SUZ-C PF12901.2 KUM57823.1 - 0.0017 17.9 3.1 0.0047 16.5 2.2 1.8 1 0 0 1 1 1 1 SUZ-C motif SUZ PF12752.2 KUM57823.1 - 0.0022 18.4 2.8 0.0022 18.4 1.9 4.5 2 1 1 3 3 3 1 SUZ domain Creb_binding PF09030.5 KUM57825.1 - 0.031 14.4 3.5 0.08 13.1 2.4 1.6 1 0 0 1 1 1 0 Creb binding CwfJ_C_1 PF04677.10 KUM57826.1 - 9.9e-30 102.7 0.0 8e-29 99.7 0.0 2.1 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 KUM57826.1 - 1.2e-23 83.4 0.0 3.2e-23 82.0 0.0 1.8 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 ATP_bind_1 PF03029.12 KUM57827.1 - 7.5e-77 258.0 0.0 9.7e-77 257.7 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 KUM57827.1 - 2.7e-05 23.6 0.0 0.00062 19.2 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 KUM57827.1 - 0.00022 20.7 0.0 0.00032 20.2 0.0 1.3 1 1 0 1 1 1 1 AAA-like domain MMR_HSR1 PF01926.18 KUM57827.1 - 0.00023 21.0 0.0 0.0007 19.5 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase ArgK PF03308.11 KUM57827.1 - 0.00023 20.0 0.0 0.1 11.3 0.0 2.4 2 0 0 2 2 2 2 ArgK protein AAA_22 PF13401.1 KUM57827.1 - 0.00028 21.0 0.0 0.00082 19.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KUM57827.1 - 0.00064 20.2 0.0 0.97 9.9 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein PRK PF00485.13 KUM57827.1 - 0.0012 18.4 0.1 0.056 12.9 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 KUM57827.1 - 0.0028 17.5 0.0 0.0059 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 KUM57827.1 - 0.0029 17.0 0.0 0.014 14.8 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NACHT PF05729.7 KUM57827.1 - 0.0037 16.9 0.0 0.0091 15.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain MobB PF03205.9 KUM57827.1 - 0.0046 16.6 0.0 0.0091 15.7 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KUM57827.1 - 0.0047 17.7 0.6 0.014 16.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain FeoB_N PF02421.13 KUM57827.1 - 0.0066 15.7 0.0 0.18 11.0 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B Methyltransf_32 PF13679.1 KUM57827.1 - 0.0087 15.7 0.0 0.23 11.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain AAA_30 PF13604.1 KUM57827.1 - 0.009 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Arf PF00025.16 KUM57827.1 - 0.011 14.9 0.0 4.7 6.4 0.0 3.1 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA_16 PF13191.1 KUM57827.1 - 0.016 15.2 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.14 KUM57827.1 - 0.022 14.2 0.1 0.88 8.9 0.0 2.3 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 KUM57827.1 - 0.024 13.4 0.1 0.046 12.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain PduV-EutP PF10662.4 KUM57827.1 - 0.038 13.4 0.2 0.45 10.0 0.0 2.6 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.15 KUM57827.1 - 0.038 12.6 2.7 0.53 8.9 0.0 2.9 3 0 0 3 3 3 0 G-protein alpha subunit KAP_NTPase PF07693.9 KUM57827.1 - 0.044 12.7 0.2 0.17 10.8 0.2 2.0 1 1 0 1 1 1 0 KAP family P-loop domain CbiA PF01656.18 KUM57827.1 - 0.074 12.4 0.0 0.21 10.9 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.7 KUM57827.1 - 0.077 12.0 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin 2-Hacid_dh_C PF02826.14 KUM57830.1 - 2.7e-59 199.2 0.0 3.7e-59 198.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KUM57830.1 - 2.8e-14 52.7 0.0 3.7e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KUM57830.1 - 0.00038 20.3 0.3 0.00063 19.6 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 KUM57830.1 - 0.016 14.5 0.1 0.029 13.7 0.1 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 KUM57830.1 - 0.079 13.3 0.1 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pkinase PF00069.20 KUM57831.1 - 3.5e-13 49.2 0.0 4.4e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM57831.1 - 1.3e-07 31.0 0.0 1.7e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Aldo_ket_red PF00248.16 KUM57832.1 - 1.1e-58 198.2 0.0 1.3e-58 198.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-U1 PF06220.7 KUM57833.1 - 7.2e-06 25.4 0.1 1.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 U1 zinc finger CCDC84 PF14968.1 KUM57833.1 - 0.0011 18.5 2.6 0.0014 18.1 1.8 1.4 1 1 0 1 1 1 1 Coiled coil protein 84 DivIVA PF05103.8 KUM57833.1 - 0.37 10.8 4.6 0.25 11.4 0.1 2.3 2 0 0 2 2 2 0 DivIVA protein Zn_clus PF00172.13 KUM57834.1 - 6.3e-08 32.4 8.8 6.3e-08 32.4 6.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CAP_GLY PF01302.20 KUM57835.1 - 4.9e-19 67.7 0.2 8.5e-19 67.0 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 KUM57835.1 - 1.2e-14 53.5 7.8 8.7e-07 28.4 0.4 4.9 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KUM57835.1 - 1.3e-12 47.2 9.2 2.6e-07 30.2 0.4 3.8 3 1 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 KUM57835.1 - 4.7e-09 35.0 5.8 1.3 9.3 0.0 7.0 6 1 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.1 KUM57835.1 - 3.8e-08 32.5 8.1 6.8 7.0 0.0 7.9 6 1 1 7 7 7 2 Leucine Rich repeat LRR_7 PF13504.1 KUM57835.1 - 9.9e-06 24.9 6.0 10 6.8 0.0 7.1 7 0 0 7 7 7 1 Leucine rich repeat CK2S PF15011.1 KUM57835.1 - 0.011 15.4 1.1 2.8 7.7 0.1 2.3 1 1 1 2 2 2 0 Casein Kinase 2 substrate LRR_9 PF14580.1 KUM57835.1 - 0.017 14.7 0.8 0.36 10.3 0.0 2.6 1 1 1 3 3 3 0 Leucine-rich repeat LSM PF01423.17 KUM57835.1 - 0.085 12.4 0.0 11 5.6 0.0 2.5 2 0 0 2 2 2 0 LSM domain zf-met PF12874.2 KUM57836.1 - 7.5e-06 25.9 2.2 4.5e-05 23.4 0.4 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.6 KUM57836.1 - 0.06 12.6 0.9 0.11 11.7 0.6 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Pkinase PF00069.20 KUM57837.1 - 4.3e-53 180.1 0.1 2.6e-37 128.3 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KUM57837.1 - 2.6e-24 85.6 0.6 3.2e-19 69.0 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KUM57837.1 - 5.8e-05 22.2 0.0 0.00012 21.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KUM57837.1 - 9.8e-05 22.1 0.1 0.0037 17.0 0.0 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KUM57837.1 - 0.00017 20.7 0.0 0.00036 19.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KUM57837.1 - 0.0044 15.9 0.1 0.01 14.6 0.0 1.5 2 0 0 2 2 2 1 Seadornavirus VP7 Pkinase_C PF00433.19 KUM57837.1 - 0.016 15.7 0.0 0.045 14.2 0.0 1.8 1 0 0 1 1 1 0 Protein kinase C terminal domain Pox_ser-thr_kin PF05445.6 KUM57837.1 - 0.089 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PAT1 PF09770.4 KUM57837.1 - 4.6 5.3 22.6 7.1 4.7 15.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GST_N_3 PF13417.1 KUM57838.1 - 1.9e-24 85.6 0.0 3.6e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KUM57838.1 - 2.1e-16 59.6 0.0 3.8e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KUM57838.1 - 4.1e-06 26.5 0.0 2.4e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KUM57838.1 - 1.3e-05 25.1 0.1 3.9e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KUM57838.1 - 0.0011 19.3 0.0 0.0022 18.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 KUM57838.1 - 0.0031 17.4 0.1 0.019 14.9 0.0 2.4 3 0 0 3 3 3 1 Glutaredoxin Dioxygenase_C PF00775.16 KUM57840.1 - 9e-09 34.8 0.1 2.3e-08 33.5 0.1 1.7 1 0 0 1 1 1 1 Dioxygenase Glyco_hydro_3 PF00933.16 KUM57842.1 - 8.1e-86 287.6 0.0 1.2e-85 287.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KUM57842.1 - 1.1e-52 178.8 0.2 6e-52 176.4 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KUM57842.1 - 1.7e-21 75.9 0.0 3.4e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Sugar_tr PF00083.19 KUM57843.1 - 3.2e-129 431.4 29.3 3.7e-129 431.2 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM57843.1 - 7.4e-25 87.3 57.1 9.5e-22 77.1 21.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3154 PF11351.3 KUM57843.1 - 0.044 13.5 4.2 0.19 11.4 0.9 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3154) PIRT PF15099.1 KUM57843.1 - 0.27 10.4 6.4 0.83 8.8 2.5 2.4 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Pyr_redox_3 PF13738.1 KUM57844.1 - 1.5e-23 83.9 0.0 4.4e-23 82.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KUM57844.1 - 1.6e-09 37.1 0.0 2.4e-05 23.4 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 KUM57844.1 - 4.5e-08 31.7 0.0 1.3e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 KUM57844.1 - 1e-05 25.3 0.8 0.034 13.9 0.1 3.8 3 1 1 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KUM57844.1 - 1.4e-05 24.9 0.0 0.00029 20.7 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KUM57844.1 - 0.00022 21.1 0.2 0.072 12.9 0.1 3.3 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 KUM57844.1 - 0.01 14.9 0.0 0.034 13.2 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KUM57844.1 - 0.013 15.5 0.0 0.19 11.8 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Dicistro_VP4 PF11492.3 KUM57844.1 - 0.083 12.9 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Cricket paralysis virus, VP4 DAO PF01266.19 KUM57844.1 - 0.091 11.6 4.0 2.9 6.7 0.0 2.7 2 1 0 2 2 2 0 FAD dependent oxidoreductase AA_permease_2 PF13520.1 KUM57846.1 - 5.2e-44 150.4 50.4 3.2e-33 114.8 13.8 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 KUM57846.1 - 6e-14 51.2 38.1 6.3e-12 44.5 10.3 2.1 2 0 0 2 2 2 2 Amino acid permease adh_short PF00106.20 KUM57848.1 - 9.6e-25 87.4 1.3 1.3e-24 86.9 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM57848.1 - 5.6e-18 65.5 0.0 6.7e-18 65.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM57848.1 - 1.3e-08 34.7 0.4 2.1e-08 34.0 0.3 1.3 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KUM57848.1 - 0.00036 20.2 0.1 0.00069 19.3 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 KUM57848.1 - 0.0068 16.9 0.0 0.026 15.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain THF_DHG_CYH_C PF02882.14 KUM57848.1 - 0.013 14.6 0.2 0.035 13.1 0.0 1.8 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 KUM57848.1 - 0.016 14.9 0.8 0.11 12.2 0.2 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Saccharop_dh PF03435.13 KUM57848.1 - 0.029 13.3 0.1 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 KUM57848.1 - 0.034 14.1 0.6 0.093 12.7 0.4 1.7 1 1 0 1 1 1 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 KUM57848.1 - 0.056 12.3 0.0 0.083 11.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_12 PF08242.7 KUM57848.1 - 0.073 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Gln-synt_C PF00120.19 KUM57849.1 - 1.4e-09 37.5 0.0 1.8e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_C PF00120.19 KUM57850.1 - 3.6e-29 101.6 0.0 4.7e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Malate_synthase PF01274.17 KUM57851.1 - 2.3e-233 774.9 0.0 2.6e-233 774.7 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Chitin_bind_3 PF03067.10 KUM57852.1 - 1.1e-10 42.1 0.1 1.4e-06 28.7 0.0 2.2 1 1 0 2 2 2 2 Chitin binding domain C1_3 PF07649.7 KUM57855.1 - 0.055 13.5 1.2 1.9 8.5 0.1 2.5 2 0 0 2 2 2 0 C1-like domain Zn_ribbon_recom PF13408.1 KUM57855.1 - 2.2 8.6 5.5 4.4 7.6 3.8 1.6 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain NmrA PF05368.8 KUM57856.1 - 4.9e-16 58.6 0.0 6.6e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KUM57856.1 - 3.4e-07 30.4 0.0 5.6e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Methyltransf_11 PF08241.7 KUM57856.1 - 0.018 15.5 0.0 0.037 14.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 KUM57856.1 - 0.023 14.6 0.0 0.05 13.5 0.0 1.7 1 1 0 1 1 1 0 short chain dehydrogenase Methyltransf_12 PF08242.7 KUM57856.1 - 0.023 15.1 0.0 0.049 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.13 KUM57856.1 - 0.06 13.3 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Cupin_7 PF12973.2 KUM57857.1 - 6.6e-11 41.9 0.1 9.5e-11 41.3 0.1 1.2 1 0 0 1 1 1 1 ChrR Cupin-like domain DUF4437 PF14499.1 KUM57857.1 - 0.085 11.7 0.4 0.14 11.0 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) Chitin_bind_4 PF00379.18 KUM57857.1 - 0.17 12.2 1.0 0.51 10.6 0.0 2.2 2 0 0 2 2 2 0 Insect cuticle protein DUF1005 PF06219.7 KUM57858.1 - 3.7 6.1 8.3 0.93 8.0 3.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1005) Glyco_hydro_75 PF07335.6 KUM57859.1 - 1.2e-44 151.9 0.1 1.9e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 EB PF01683.13 KUM57859.1 - 2.7 8.1 13.2 0.91 9.6 6.3 2.1 2 0 0 2 2 2 0 EB module Pkinase PF00069.20 KUM57860.1 - 7.7e-62 208.7 0.0 1.1e-61 208.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM57860.1 - 3.9e-33 114.6 0.0 5.3e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM57860.1 - 2.7e-07 29.8 0.0 3.9e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KUM57860.1 - 0.0015 18.2 0.3 0.0015 18.2 0.2 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KUM57860.1 - 0.01 14.9 0.0 0.02 13.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF605 PF04652.11 KUM57860.1 - 4.4 6.6 12.4 6 6.1 8.6 1.2 1 0 0 1 1 1 0 Vta1 like NPV_P10 PF05531.7 KUM57861.1 - 9.5 6.5 0.0 9.5 6.5 0.0 5.8 7 1 0 8 8 8 0 Nucleopolyhedrovirus P10 protein DUF294_C PF10335.4 KUM57862.1 - 0.092 12.3 0.1 2.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Putative nucleotidyltransferase substrate binding domain Metallophos PF00149.23 KUM57863.1 - 2.2e-10 40.2 0.0 3.6e-10 39.5 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KUM57863.1 - 1.4e-08 34.6 0.2 4.1e-08 33.2 0.1 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ADH_zinc_N PF00107.21 KUM57864.1 - 2e-30 104.9 0.7 3e-30 104.4 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KUM57864.1 - 9.9e-19 68.4 0.1 2.2e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM57864.1 - 6.2e-12 45.2 0.0 1.6e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 KUM57864.1 - 8.8e-05 22.1 0.0 0.00016 21.2 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 KUM57864.1 - 0.03 13.4 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CMAS PF02353.15 KUM57864.1 - 0.036 13.1 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TrkA_N PF02254.13 KUM57864.1 - 0.045 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain ELFV_dehydrog PF00208.16 KUM57864.1 - 0.058 12.9 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Kdo PF06293.9 KUM57866.1 - 5e-06 25.7 0.0 9.2e-06 24.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KUM57866.1 - 0.0044 16.7 0.8 0.11 12.2 0.2 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 KUM57866.1 - 0.12 11.5 0.0 0.39 9.8 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain Aa_trans PF01490.13 KUM57867.1 - 9.4e-34 116.5 32.5 1.5e-19 69.7 10.7 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein AMP-binding PF00501.23 KUM57868.1 - 9.8e-88 294.3 0.0 1.9e-87 293.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 KUM57868.1 - 3.2e-71 239.8 0.5 1.7e-70 237.3 0.0 2.4 3 0 0 3 3 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KUM57868.1 - 1.8e-53 181.9 0.0 5.1e-53 180.4 0.0 1.7 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KUM57868.1 - 8e-53 178.7 2.2 1.2e-51 174.9 0.0 3.5 4 0 0 4 4 3 1 KR domain Condensation PF00668.15 KUM57868.1 - 5.6e-50 169.8 1.7 1.2e-49 168.7 1.1 1.5 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.1 KUM57868.1 - 2.6e-47 161.4 0.7 4.9e-47 160.5 0.5 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KUM57868.1 - 1.2e-44 152.1 0.1 9.1e-43 146.0 0.0 3.4 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KUM57868.1 - 5.3e-29 100.4 0.0 3.8e-28 97.7 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 KUM57868.1 - 5.1e-26 91.1 0.0 1.1e-24 86.7 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 KUM57868.1 - 6.9e-21 74.5 0.0 2.4e-20 72.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KUM57868.1 - 4.7e-16 58.8 0.1 2.8e-07 30.7 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 KUM57868.1 - 2e-12 47.2 0.0 6.8e-12 45.5 0.0 2.0 1 0 0 1 1 1 1 HxxPF-repeated domain Methyltransf_31 PF13847.1 KUM57868.1 - 6.9e-11 41.9 0.0 2.1e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM57868.1 - 4.8e-10 39.7 0.0 2e-09 37.8 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM57868.1 - 1.5e-09 37.7 0.0 4.8e-09 36.1 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM57868.1 - 2.5e-09 37.7 0.0 1.6e-08 35.0 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain Epimerase PF01370.16 KUM57868.1 - 2.5e-09 36.9 0.0 5e-07 29.3 0.0 2.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KUM57868.1 - 4.2e-06 25.6 0.0 3.9e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.18 KUM57868.1 - 4.5e-06 25.8 0.1 9.8e-06 24.7 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 KUM57868.1 - 6.5e-06 25.4 0.1 1.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family AMP-binding_C PF13193.1 KUM57868.1 - 1.3e-05 26.0 0.4 7.1e-05 23.6 0.0 2.5 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain RmlD_sub_bind PF04321.12 KUM57868.1 - 0.0043 15.9 0.0 0.013 14.4 0.0 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain Methyltransf_16 PF10294.4 KUM57868.1 - 0.023 14.1 0.0 0.051 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Glyco_hydro_42M PF08532.5 KUM57868.1 - 0.061 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain ADH_N PF08240.7 KUM57869.1 - 5.4e-06 26.1 0.0 0.00021 21.0 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM57869.1 - 0.0036 16.8 0.0 0.023 14.2 0.0 2.3 2 1 0 2 2 2 1 Zinc-binding dehydrogenase p450 PF00067.17 KUM57870.1 - 2.3e-34 118.7 0.0 2.9e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KUM57871.1 - 7.6e-29 100.5 0.0 1.6e-28 99.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 B56 PF01603.15 KUM57872.1 - 9e-173 574.5 5.6 1.1e-172 574.2 3.9 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Macoilin PF09726.4 KUM57872.1 - 0.46 8.7 2.8 0.61 8.2 2.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Herpes_UL95 PF03038.9 KUM57874.1 - 0.092 11.6 0.3 8.4 5.1 0.0 2.1 2 0 0 2 2 2 0 UL95 family TPR_11 PF13414.1 KUM57876.1 - 5.8e-30 102.7 10.8 2.3e-08 33.5 0.0 8.2 6 2 1 7 7 7 7 TPR repeat TPR_2 PF07719.12 KUM57876.1 - 9.7e-29 96.9 9.0 0.0035 17.1 0.2 10.6 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_1 PF00515.23 KUM57876.1 - 5e-28 95.5 0.1 0.00038 19.9 0.2 10.0 9 0 0 9 9 9 7 Tetratricopeptide repeat Apc3 PF12895.2 KUM57876.1 - 7.5e-25 86.8 10.7 1.7e-19 69.7 0.6 5.4 6 0 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KUM57876.1 - 3e-18 65.9 6.8 1.1e-05 25.7 0.0 7.9 6 2 3 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.1 KUM57876.1 - 1.8e-17 63.0 20.4 1.2e-06 28.3 0.1 9.5 10 1 1 11 11 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 KUM57876.1 - 7.1e-17 60.3 13.8 0.42 11.3 0.2 10.7 8 3 3 11 11 10 2 Tetratricopeptide repeat TPR_16 PF13432.1 KUM57876.1 - 3.6e-14 52.9 21.8 2.8e-05 24.6 0.4 8.9 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 KUM57876.1 - 1.7e-11 43.0 0.0 0.91 9.4 0.0 7.6 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.1 KUM57876.1 - 2.8e-08 33.6 6.2 1.9 9.1 0.1 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 KUM57876.1 - 3.5e-08 32.6 15.1 1.1 9.1 0.0 9.5 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.1 KUM57876.1 - 1.4e-07 31.1 0.2 0.29 11.4 0.0 7.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.1 KUM57876.1 - 2e-05 24.3 17.0 0.15 12.0 0.0 8.6 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_9 PF13371.1 KUM57876.1 - 0.0026 17.5 13.2 16 5.4 0.0 6.9 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 KUM57876.1 - 0.044 14.2 18.5 19 6.0 0.1 8.0 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_21 PF09976.4 KUM57876.1 - 1.6 8.6 8.8 25 4.7 0.0 4.7 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.7 KUM57876.1 - 5.7 6.8 5.7 17 5.3 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF572 PF04502.8 KUM57877.1 - 1.4e-63 215.1 30.6 6.7e-63 212.8 21.2 1.7 1 1 0 1 1 1 1 Family of unknown function (DUF572) zinc_ribbon_2 PF13240.1 KUM57877.1 - 0.03 13.8 0.4 0.063 12.7 0.3 1.6 1 0 0 1 1 1 0 zinc-ribbon domain SSP160 PF06933.6 KUM57877.1 - 0.8 7.6 15.5 1.4 6.8 10.7 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FAT PF02259.18 KUM57878.1 - 6.7e-74 248.9 8.3 1.6e-73 247.6 5.7 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 KUM57878.1 - 2.1e-30 105.9 0.3 1e-29 103.6 0.1 2.3 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KUM57878.1 - 3.9e-08 32.5 0.1 1.1e-07 31.1 0.1 1.8 1 0 0 1 1 1 1 FATC domain Pkinase PF00069.20 KUM57879.1 - 0.011 14.9 0.0 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.12 KUM57879.1 - 0.013 14.6 0.0 0.024 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase Tau95 PF09734.4 KUM57881.1 - 3.3e-73 246.7 0.0 3.7e-73 246.5 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit Cyclin_N PF00134.18 KUM57882.1 - 2.1e-35 121.0 0.3 2.1e-35 121.0 0.2 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KUM57882.1 - 4.9e-15 55.5 1.4 1.6e-14 53.8 1.0 1.9 1 0 0 1 1 1 1 Cyclin, C-terminal domain DSPc PF00782.15 KUM57883.1 - 4.2e-23 81.3 0.0 8.1e-21 73.9 0.0 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KUM57883.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Methyltransf_18 PF12847.2 KUM57884.1 - 1.7e-17 64.0 0.0 3e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM57884.1 - 3.8e-11 42.8 0.0 1.5e-07 31.0 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 KUM57884.1 - 1.1e-09 38.2 0.0 1.8e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM57884.1 - 2.5e-07 31.0 0.1 4.5e-05 23.8 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KUM57884.1 - 1.4e-06 28.3 0.0 4.3e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM57884.1 - 1.2e-05 25.7 0.9 4.3e-05 23.8 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 KUM57884.1 - 0.00034 20.6 0.0 0.00048 20.1 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 KUM57884.1 - 0.0005 20.3 0.0 0.0023 18.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 KUM57884.1 - 0.0036 17.0 0.0 0.0056 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KUM57884.1 - 0.005 16.2 0.0 0.012 14.9 0.0 1.5 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW MTS PF05175.9 KUM57884.1 - 0.0057 16.0 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain SDA1 PF05285.7 KUM57884.1 - 0.0093 15.2 5.7 0.013 14.8 4.0 1.1 1 0 0 1 1 1 1 SDA1 PCMT PF01135.14 KUM57884.1 - 0.028 13.9 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NESP55 PF06390.7 KUM57884.1 - 0.35 10.2 14.5 0.16 11.3 5.9 2.1 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) TRAP_alpha PF03896.11 KUM57884.1 - 0.49 9.3 6.5 1.3 7.9 1.6 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit PBP1_TM PF14812.1 KUM57884.1 - 4.6 7.6 10.5 5.4 7.3 2.8 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 KUM57884.1 - 5.7 7.2 10.7 31 4.8 4.0 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Methyltransf_16 PF10294.4 KUM57885.1 - 0.0011 18.4 0.0 0.0013 18.2 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase WD40 PF00400.27 KUM57886.1 - 4.4e-14 51.7 8.9 0.077 12.9 0.0 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ADH_N PF08240.7 KUM57887.1 - 1.1e-28 99.1 4.1 1.8e-28 98.4 1.4 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Yippee-Mis18 PF03226.9 KUM57887.1 - 3e-23 81.6 0.8 3e-23 81.6 0.5 1.6 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly ADH_zinc_N PF00107.21 KUM57887.1 - 8.8e-20 70.5 0.0 2.3e-19 69.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KUM57887.1 - 0.00057 19.4 0.4 0.0017 17.9 0.3 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.1 KUM57887.1 - 0.03 15.2 0.0 0.085 13.7 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase KH_1 PF00013.24 KUM57888.1 - 6.1e-39 131.4 9.9 2.8e-15 55.6 0.1 3.1 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KUM57888.1 - 1.2e-29 101.3 11.4 4.5e-11 42.1 1.0 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KUM57888.1 - 2.8e-09 36.4 10.5 0.0028 17.1 0.5 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KUM57888.1 - 5.6e-08 32.3 5.4 0.074 12.7 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 KUM57888.1 - 0.0006 19.5 4.0 0.99 9.2 0.0 3.3 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 KUM57888.1 - 0.0022 17.4 0.1 0.85 9.0 0.0 3.2 3 0 0 3 3 3 1 dUTPase GARS_C PF02843.11 KUM57888.1 - 0.034 14.3 1.0 2.3 8.4 0.1 3.0 3 1 0 3 3 3 0 Phosphoribosylglycinamide synthetase, C domain cNMP_binding PF00027.24 KUM57890.1 - 8.9e-17 60.6 0.0 1.1e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain BRCT PF00533.21 KUM57891.1 - 6.3e-33 112.7 0.0 2e-09 37.4 0.0 6.5 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KUM57891.1 - 3.3e-30 103.7 0.5 1.1e-19 70.0 0.3 5.6 5 1 0 5 5 5 4 twin BRCT domain HSP70 PF00012.15 KUM57892.1 - 2.6e-09 35.5 0.1 8.8e-08 30.5 0.0 2.5 3 0 0 3 3 3 2 Hsp70 protein Coagulase PF08764.5 KUM57893.1 - 0.042 13.7 0.6 0.042 13.7 0.4 1.5 2 0 0 2 2 2 0 Staphylococcus aureus coagulase DUF745 PF05335.8 KUM57893.1 - 0.18 11.3 1.5 0.35 10.3 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF4164 PF13747.1 KUM57893.1 - 8.8 6.5 11.8 1.4 9.1 3.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Trypan_PARP PF05887.6 KUM57894.1 - 0.061 13.1 1.2 0.1 12.4 0.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CN_hydrolase PF00795.17 KUM57895.1 - 1.8e-27 95.9 0.0 4.3e-27 94.6 0.0 1.5 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase RNB PF00773.14 KUM57896.1 - 3.2e-95 319.1 0.0 4.8e-95 318.5 0.0 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 KUM57896.1 - 2.7e-07 30.7 0.3 1.4e-06 28.4 0.1 2.3 2 1 0 2 2 2 1 PIN domain Dna2 PF08696.6 KUM57897.1 - 3.1e-68 229.1 0.3 5.3e-68 228.4 0.2 1.3 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 KUM57897.1 - 8.2e-51 172.2 0.0 1.2e-50 171.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KUM57897.1 - 3.1e-41 141.5 0.3 1.1e-19 71.0 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 KUM57897.1 - 2.7e-14 53.1 0.0 5.8e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KUM57897.1 - 9.2e-12 44.5 0.1 3.6e-11 42.6 0.1 2.1 1 0 0 1 1 1 1 Part of AAA domain PDDEXK_1 PF12705.2 KUM57897.1 - 3.6e-11 42.9 0.3 8.7e-11 41.6 0.1 1.7 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.12 KUM57897.1 - 3e-07 30.4 0.1 9e-07 28.9 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.13 KUM57897.1 - 1.3e-05 24.8 0.4 0.36 10.3 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 KUM57897.1 - 0.00013 21.4 0.1 0.00025 20.4 0.0 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 KUM57897.1 - 0.00014 21.5 0.0 0.00028 20.5 0.0 1.5 1 0 0 1 1 1 1 Helicase CbiA PF01656.18 KUM57897.1 - 0.00049 19.5 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF911 PF06023.7 KUM57897.1 - 0.0007 18.8 0.1 0.0014 17.8 0.0 1.4 1 0 0 1 1 1 1 Archaeal protein of unknown function (DUF911) SRP54 PF00448.17 KUM57897.1 - 0.00084 18.8 0.1 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain MobB PF03205.9 KUM57897.1 - 0.0012 18.5 0.1 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KUM57897.1 - 0.0014 18.6 0.0 0.004 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain PIF1 PF05970.9 KUM57897.1 - 0.0034 16.3 0.1 0.011 14.7 0.1 1.8 1 1 0 1 1 1 1 PIF1-like helicase AAA_25 PF13481.1 KUM57897.1 - 0.0065 15.8 0.0 0.04 13.3 0.0 2.2 3 0 0 3 3 2 1 AAA domain DUF2075 PF09848.4 KUM57897.1 - 0.0073 15.3 0.0 0.018 14.0 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DUF87 PF01935.12 KUM57897.1 - 0.028 14.2 0.2 0.1 12.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_22 PF13401.1 KUM57897.1 - 0.043 13.9 0.2 0.23 11.6 0.0 2.3 2 1 0 2 2 1 0 AAA domain AAA_10 PF12846.2 KUM57897.1 - 0.045 13.1 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain FtsK_SpoIIIE PF01580.13 KUM57897.1 - 0.061 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ArgK PF03308.11 KUM57897.1 - 0.094 11.4 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 ArgK protein RNA_helicase PF00910.17 KUM57897.1 - 0.12 12.5 0.1 5.5 7.2 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA PF00004.24 KUM57897.1 - 0.13 12.4 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ESSS PF10183.4 KUM57898.1 - 2.8e-31 108.0 0.1 3.3e-31 107.7 0.0 1.0 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3961 PF13106.1 KUM57898.1 - 0.73 9.4 3.4 1.2 8.7 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) Methyltransf_4 PF02390.12 KUM57899.1 - 6.1e-47 159.2 0.0 2.7e-34 117.9 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 KUM57899.1 - 4.4e-05 24.0 0.0 8.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM57899.1 - 0.00088 19.7 0.0 0.0023 18.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain FmrO PF07091.6 KUM57899.1 - 0.0017 17.4 0.0 0.0032 16.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_32 PF13679.1 KUM57899.1 - 0.0084 15.8 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KUM57899.1 - 0.011 15.7 0.0 0.028 14.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 KUM57899.1 - 0.023 15.0 0.0 0.092 13.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 KUM57899.1 - 0.023 14.0 0.0 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_31 PF13847.1 KUM57899.1 - 0.042 13.4 0.0 0.089 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KUM57899.1 - 0.063 13.7 0.0 1.3 9.5 0.0 2.8 3 0 0 3 3 3 0 Methyltransferase domain ESCRT-II PF05871.7 KUM57900.1 - 5.9e-52 175.2 0.0 7.8e-52 174.8 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit MFS_1 PF07690.11 KUM57901.1 - 3.5e-24 85.1 45.1 9.6e-24 83.7 31.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily LIM PF00412.17 KUM57902.1 - 3.6e-26 91.0 27.7 1.7e-10 40.7 3.2 3.8 3 1 0 3 3 3 3 LIM domain DUF2321 PF10083.4 KUM57902.1 - 6 6.3 9.2 0.14 11.6 0.8 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) MFS_1 PF07690.11 KUM57903.1 - 2.9e-35 121.6 67.3 6.7e-33 113.8 44.5 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DcpS PF05652.7 KUM57904.1 - 1.3e-28 99.5 0.0 2e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.3 KUM57904.1 - 3.4e-28 98.1 0.0 6.1e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Cupin_5 PF06172.6 KUM57905.1 - 6.1e-37 126.6 0.0 7.4e-37 126.3 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) RNase_T PF00929.19 KUM57907.1 - 4.6e-29 101.8 0.0 6.9e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Nop53 PF07767.6 KUM57908.1 - 5.6e-113 377.8 25.5 6.8e-113 377.5 17.7 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Peptidase_C37 PF05416.7 KUM57908.1 - 1.8 6.7 7.7 2.8 6.1 5.3 1.3 1 0 0 1 1 1 0 Southampton virus-type processing peptidase RNase_H2_suC PF08615.6 KUM57909.1 - 7e-31 106.8 0.0 9e-31 106.5 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Peptidase_C12 PF01088.16 KUM57910.1 - 7.3e-62 208.3 0.0 8.6e-62 208.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Cu-oxidase_3 PF07732.10 KUM57912.1 - 3.3e-11 42.9 0.0 6e-08 32.4 0.0 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KUM57912.1 - 1.9e-09 37.1 0.1 0.0033 16.9 0.0 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.1 KUM57912.1 - 0.0056 16.5 0.0 3.9 7.4 0.0 2.4 2 0 0 2 2 2 2 Cupredoxin-like domain Sugar_tr PF00083.19 KUM57913.1 - 6.3e-63 212.9 32.8 3.3e-62 210.5 22.7 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM57913.1 - 3.8e-16 58.7 41.8 2.7e-13 49.3 16.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KUM57913.1 - 0.001 17.5 5.4 0.001 17.5 3.7 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein Peptidase_MA_2 PF13485.1 KUM57914.1 - 0.0016 18.4 0.3 0.0039 17.2 0.2 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily Indigoidine_A PF04227.7 KUM57915.1 - 2.6e-111 371.5 0.1 3.7e-111 371.0 0.1 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 KUM57915.1 - 1.1e-15 57.5 0.4 3.1e-10 39.6 0.0 2.5 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Ribophorin_I PF04597.9 KUM57916.1 - 2.3e-149 497.6 0.0 2.8e-149 497.3 0.0 1.1 1 0 0 1 1 1 1 Ribophorin I Myb_Cef PF11831.3 KUM57917.1 - 2.6e-67 226.4 0.9 2.6e-67 226.4 0.6 3.9 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 KUM57917.1 - 2.8e-20 72.0 4.0 2.3e-09 37.1 0.2 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KUM57917.1 - 7.7e-20 70.7 5.1 2.7e-13 49.8 0.8 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain HTH_AsnC-type PF13404.1 KUM57917.1 - 0.0097 15.4 2.3 0.23 11.0 0.0 2.9 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain Fungal_trans_2 PF11951.3 KUM57918.1 - 6.6e-16 57.8 6.4 1e-15 57.2 4.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM57919.1 - 2e-09 37.1 10.3 5.3e-09 35.8 7.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.1 KUM57920.1 - 3.9e-47 160.7 50.0 4.7e-47 160.4 34.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM57920.1 - 8.1e-21 73.9 41.4 1.1e-20 73.4 28.7 1.1 1 0 0 1 1 1 1 Amino acid permease Pox_P21 PF05313.7 KUM57920.1 - 0.34 10.1 4.5 0.37 10.0 1.5 2.1 2 0 0 2 2 2 0 Poxvirus P21 membrane protein 2OG-FeII_Oxy PF03171.15 KUM57921.1 - 2.6e-13 50.0 0.0 3.5e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 KUM57922.1 - 2.9e-11 42.7 1.0 5.3e-11 41.8 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ring_hydroxyl_A PF00848.14 KUM57923.1 - 3.7e-22 79.0 8.5 6e-20 71.7 4.6 2.8 2 1 0 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 KUM57923.1 - 2.4e-15 55.8 0.0 4.4e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Peptidase_M3 PF01432.15 KUM57924.1 - 1.8e-08 33.8 0.1 8.3e-08 31.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M3 DUF3581 PF12119.3 KUM57924.1 - 0.068 12.3 0.0 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3581) Fungal_trans PF04082.13 KUM57925.1 - 4.9e-13 48.5 0.0 9.3e-13 47.6 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Phosphoesterase PF04185.9 KUM57926.1 - 1.1e-76 258.5 2.1 1.5e-76 258.0 1.4 1.2 1 0 0 1 1 1 1 Phosphoesterase family Pyr_redox_3 PF13738.1 KUM57928.1 - 1.2e-15 58.1 0.0 6.4e-15 55.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KUM57928.1 - 1.7e-06 26.5 0.1 0.00037 18.8 0.0 2.9 3 1 0 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KUM57928.1 - 4.8e-05 22.4 0.0 0.0015 17.4 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KUM57928.1 - 0.00022 21.0 0.6 0.12 12.1 0.1 3.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KUM57928.1 - 0.0036 17.2 0.0 0.48 10.2 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM57928.1 - 0.0074 16.2 0.0 1.7 8.6 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain MHYT PF03707.11 KUM57928.1 - 0.092 12.8 0.9 0.22 11.6 0.6 1.6 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat HI0933_like PF03486.9 KUM57928.1 - 0.25 9.7 0.3 1.4 7.3 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Ank_2 PF12796.2 KUM57929.1 - 2.2e-33 114.4 2.3 2.3e-18 66.2 0.0 3.2 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KUM57929.1 - 4.1e-29 98.9 13.9 4.8e-05 22.9 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 KUM57929.1 - 6.3e-23 78.5 6.6 0.0017 18.4 0.0 7.2 7 0 0 7 7 6 5 Ankyrin repeat Ank_4 PF13637.1 KUM57929.1 - 2.6e-22 78.7 3.8 4e-07 30.3 0.1 5.7 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM57929.1 - 6.6e-17 61.1 6.0 0.0027 17.9 0.3 5.6 1 1 3 5 5 5 5 Ankyrin repeats (many copies) NACHT PF05729.7 KUM57929.1 - 1.7e-09 37.5 0.4 5.5e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KUM57929.1 - 0.00068 19.6 0.0 0.0031 17.5 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KUM57929.1 - 0.0016 18.5 0.0 0.0052 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KUM57929.1 - 0.0049 16.5 0.0 0.0086 15.7 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 KUM57929.1 - 0.02 14.7 0.1 0.31 10.9 0.0 2.4 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KUM57929.1 - 0.042 12.6 0.1 0.15 10.8 0.0 1.8 1 1 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 KUM57929.1 - 0.062 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ThiW PF09512.5 KUM57929.1 - 2.1 8.1 4.1 1.3 8.8 0.3 2.3 2 1 1 3 3 3 0 Thiamine-precursor transporter protein (ThiW) Zn_clus PF00172.13 KUM57930.1 - 1.9e-09 37.2 9.4 2.4e-09 36.9 6.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transketolase_N PF00456.16 KUM57931.1 - 1.8e-121 405.0 0.0 2.6e-121 404.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KUM57931.1 - 1e-43 148.8 0.1 1.9e-43 148.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 KUM57931.1 - 4.3e-08 32.4 0.0 2.5e-06 26.6 0.0 2.2 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.15 KUM57931.1 - 6.5e-06 26.0 0.0 1.5e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.15 KUM57931.1 - 1.2e-05 24.2 0.1 3.4e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Dehydrogenase E1 component ADH_N PF08240.7 KUM57932.1 - 2.5e-30 104.4 1.5 8.6e-30 102.7 0.6 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM57932.1 - 5.2e-14 51.9 0.0 7.9e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 KUM57932.1 - 0.013 15.5 0.1 0.068 13.2 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KUM57932.1 - 0.14 12.1 0.0 0.36 10.8 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain Trp_syntA PF00290.15 KUM57934.1 - 1.6e-65 220.2 0.0 2.3e-65 219.6 0.0 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 KUM57934.1 - 1.8e-38 132.5 0.2 2.7e-38 131.9 0.2 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MFS_1 PF07690.11 KUM57936.1 - 3.5e-23 81.9 31.8 3.5e-23 81.9 22.1 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM57936.1 - 3.6e-06 25.8 9.2 3.6e-06 25.8 6.4 3.1 3 0 0 3 3 3 1 Sugar (and other) transporter Glyco_hydro_31 PF01055.21 KUM57938.1 - 1.8e-122 409.3 0.3 2.4e-122 408.9 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KUM57938.1 - 2.2e-21 75.5 0.0 8e-20 70.4 0.1 2.8 2 0 0 2 2 2 1 Galactose mutarotase-like Glyoxalase_5 PF14696.1 KUM57938.1 - 0.0065 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Fungal_trans PF04082.13 KUM57939.1 - 3.3e-21 75.3 0.0 6.2e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM57939.1 - 1.9e-07 30.8 12.5 3.2e-07 30.1 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3608 PF12257.3 KUM57940.1 - 1.9e-74 250.1 0.0 2.7e-74 249.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 KUM57940.1 - 1.4e-29 101.6 0.8 2.6e-29 100.7 0.6 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) MFS_1 PF07690.11 KUM57941.1 - 2e-41 141.9 32.3 2e-41 141.9 22.4 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.8 KUM57941.1 - 0.0029 15.8 6.4 0.0049 15.0 4.4 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector Fungal_trans PF04082.13 KUM57942.1 - 2.3e-12 46.3 1.5 4.8e-12 45.2 1.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM57942.1 - 5.2e-07 29.4 11.2 9.7e-07 28.6 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FNIP_N PF14636.1 KUM57943.1 - 2.7e-20 73.1 0.0 2.7e-20 73.1 0.0 4.5 3 1 1 4 4 4 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.1 KUM57943.1 - 0.24 10.9 0.0 0.46 10.0 0.0 1.4 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain LIM_bind PF01803.11 KUM57945.1 - 3.8e-77 258.6 0.1 3.8e-77 258.6 0.1 3.9 3 1 1 4 4 4 1 LIM-domain binding protein DUF663 PF04950.7 KUM57946.1 - 9.3e-95 317.0 0.0 1.5e-94 316.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KUM57946.1 - 1.3e-23 82.3 0.0 2.7e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain SNAP PF14938.1 KUM57947.1 - 6.4e-116 386.4 11.1 7.4e-116 386.2 7.7 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 KUM57947.1 - 1e-05 25.3 18.4 0.021 14.7 5.3 4.3 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 KUM57947.1 - 0.00034 20.1 10.5 0.074 12.8 0.4 5.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KUM57947.1 - 0.0012 18.5 16.7 0.18 11.4 1.4 4.0 3 1 1 4 4 4 2 TPR repeat TPR_1 PF00515.23 KUM57947.1 - 0.0041 16.6 19.7 0.2 11.3 0.3 6.4 6 1 1 7 7 7 2 Tetratricopeptide repeat DUF2811 PF10929.3 KUM57947.1 - 0.012 15.5 0.2 0.04 13.9 0.2 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF2811) TPR_6 PF13174.1 KUM57947.1 - 0.015 15.7 12.1 1.3 9.6 0.4 5.7 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 KUM57947.1 - 0.023 15.2 11.8 0.62 10.8 1.0 4.6 2 1 3 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 KUM57947.1 - 0.032 14.0 0.9 0.032 14.0 0.6 5.6 5 1 2 7 7 7 0 Tetratricopeptide repeat NSF PF02071.15 KUM57947.1 - 0.091 13.3 17.6 0.81 10.5 0.2 7.1 7 1 1 8 8 7 0 Aromatic-di-Alanine (AdAR) repeat DFF40 PF09230.5 KUM57947.1 - 0.28 10.5 1.7 1.1 8.5 0.1 2.1 2 0 0 2 2 2 0 DNA fragmentation factor 40 kDa TPR_2 PF07719.12 KUM57947.1 - 0.72 9.9 23.4 0.89 9.6 0.4 7.1 4 3 3 8 8 8 0 Tetratricopeptide repeat cobW PF02492.14 KUM57948.1 - 3.7e-34 117.7 0.0 4.5e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 KUM57948.1 - 6.6e-06 25.0 1.6 0.00011 21.0 1.1 2.0 1 1 0 1 1 1 1 ArgK protein MMR_HSR1 PF01926.18 KUM57948.1 - 0.0063 16.4 0.0 0.012 15.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 KUM57948.1 - 0.01 16.6 0.0 0.022 15.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KUM57948.1 - 0.011 16.0 0.0 0.019 15.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.8 KUM57948.1 - 0.019 13.6 0.0 0.028 13.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_5 PF07728.9 KUM57948.1 - 0.021 14.5 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KUM57948.1 - 0.034 13.5 0.0 0.082 12.3 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein PRK PF00485.13 KUM57948.1 - 0.076 12.5 0.1 0.3 10.6 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.9 KUM57948.1 - 0.076 12.7 0.0 0.26 10.9 0.0 1.9 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 KUM57948.1 - 0.077 12.3 0.1 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain KAP_NTPase PF07693.9 KUM57948.1 - 0.11 11.4 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain ABC_tran PF00005.22 KUM57948.1 - 0.14 12.4 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 KUM57948.1 - 0.14 11.1 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Arch_ATPase PF01637.13 KUM57948.1 - 0.18 11.4 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase BING4CT PF08149.6 KUM57949.1 - 2.2e-39 132.7 0.0 1.5e-36 123.7 0.0 2.7 2 0 0 2 2 2 2 BING4CT (NUC141) domain WD40 PF00400.27 KUM57949.1 - 3.6e-05 23.4 0.0 0.0036 17.1 0.0 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF4319 PF14203.1 KUM57949.1 - 0.0016 17.8 0.0 0.0032 16.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4319) Coatomer_WDAD PF04053.9 KUM57949.1 - 0.024 13.4 0.0 0.048 12.4 0.0 1.4 1 0 0 1 1 1 0 Coatomer WD associated region DUF726 PF05277.7 KUM57950.1 - 8e-114 380.1 1.1 1.1e-113 379.6 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.15 KUM57950.1 - 2.1e-05 24.8 0.0 5.2e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 KUM57950.1 - 0.0002 21.1 0.1 0.00066 19.4 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KUM57950.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Cutinase PF01083.17 KUM57950.1 - 0.04 13.6 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 Cutinase DUF900 PF05990.7 KUM57950.1 - 0.058 12.7 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Glu-tRNAGln PF02686.10 KUM57951.1 - 2e-05 24.3 0.4 0.00013 21.6 0.3 2.1 2 0 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit TPR_12 PF13424.1 KUM57952.1 - 3.6e-74 244.7 45.1 2.1e-20 72.4 2.2 5.1 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.1 KUM57952.1 - 1.4e-52 174.1 22.1 1.6e-10 40.5 0.1 6.9 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 KUM57952.1 - 7.6e-30 101.2 23.7 6.3e-06 25.5 0.2 7.0 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_7 PF13176.1 KUM57952.1 - 7.7e-25 84.6 29.4 0.0001 21.8 0.1 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 KUM57952.1 - 1.2e-23 81.0 24.0 0.00041 20.0 0.2 6.9 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.1 KUM57952.1 - 6e-20 69.4 19.9 0.0021 17.6 0.1 6.8 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.1 KUM57952.1 - 4.8e-18 64.5 22.9 2.1e-06 27.2 0.8 5.0 3 2 0 4 4 4 3 TPR repeat TPR_14 PF13428.1 KUM57952.1 - 2.8e-15 55.4 24.0 0.019 15.5 0.1 7.5 8 0 0 8 8 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 KUM57952.1 - 5.5e-15 55.5 26.1 7.8e-05 23.2 2.2 4.9 3 1 2 5 5 4 4 Tetratricopeptide repeat TPR_4 PF07721.9 KUM57952.1 - 2.6e-13 48.9 11.4 0.07 13.5 0.1 6.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 KUM57952.1 - 4.9e-12 45.0 13.7 0.87 9.9 0.0 8.1 6 2 0 6 6 6 5 Tetratricopeptide repeat NB-ARC PF00931.17 KUM57952.1 - 2.5e-10 39.6 0.0 0.00035 19.5 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain TPR_19 PF14559.1 KUM57952.1 - 4.7e-08 33.2 17.7 0.0072 16.6 2.0 4.8 3 1 3 6 6 4 4 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 KUM57952.1 - 1.3e-06 27.6 0.5 5.3e-06 25.5 0.3 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_6 PF13174.1 KUM57952.1 - 1.4e-06 28.3 25.6 1.2 9.7 0.3 6.9 6 0 0 6 6 6 4 Tetratricopeptide repeat DUF2225 PF09986.4 KUM57952.1 - 9.8e-06 25.1 5.3 0.02 14.3 0.8 3.3 1 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) AAA_16 PF13191.1 KUM57952.1 - 6e-05 23.1 0.3 0.00023 21.2 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain Apc3 PF12895.2 KUM57952.1 - 6.9e-05 22.9 2.7 0.0066 16.5 0.1 3.9 1 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.4 KUM57952.1 - 8.5e-05 22.0 5.6 1.7 7.9 0.0 5.1 1 1 4 5 5 5 1 26S proteasome subunit RPN7 PPR PF01535.15 KUM57952.1 - 0.00061 19.5 0.7 5.8 7.1 0.0 5.7 6 0 0 6 6 5 1 PPR repeat Arch_ATPase PF01637.13 KUM57952.1 - 0.0089 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AA_kinase PF00696.23 KUM57952.1 - 0.027 14.0 0.0 0.059 12.9 0.0 1.6 1 0 0 1 1 1 0 Amino acid kinase family TPR_21 PF09976.4 KUM57952.1 - 4.6 7.1 12.9 17 5.3 1.1 4.7 3 2 2 5 5 5 0 Tetratricopeptide repeat Peptidase_M20 PF01546.23 KUM57953.1 - 2.2e-18 66.4 0.1 3.2e-18 65.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KUM57953.1 - 1.7e-11 43.8 0.0 3.5e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain ADH_zinc_N_2 PF13602.1 KUM57954.1 - 4.1e-22 79.4 0.2 8.2e-22 78.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KUM57954.1 - 2.2e-13 49.8 0.1 3.8e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM57954.1 - 0.00046 19.9 0.2 0.0018 18.0 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Fe_hyd_lg_C PF02906.9 KUM57954.1 - 0.016 14.5 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain AlaDh_PNT_C PF01262.16 KUM57954.1 - 0.019 14.5 0.8 0.036 13.6 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF3335 PF11814.3 KUM57954.1 - 0.056 12.5 0.1 0.23 10.5 0.1 1.8 2 0 0 2 2 2 0 Peptidase_C39 like family Methyltransf_2 PF00891.13 KUM57958.1 - 1.1e-28 100.1 0.0 5.2e-28 97.8 0.0 2.1 3 0 0 3 3 3 1 O-methyltransferase Methyltransf_23 PF13489.1 KUM57958.1 - 6.7e-05 22.6 0.0 0.00018 21.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_19 PF04672.7 KUM57958.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl methyltransferase HBS1_N PF08938.5 KUM57958.1 - 0.15 12.1 0.2 0.34 11.0 0.1 1.5 1 0 0 1 1 1 0 HBS1 N-terminus DIOX_N PF14226.1 KUM57959.1 - 8.8e-23 81.0 0.0 1.7e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KUM57959.1 - 1.4e-13 51.0 0.0 2.8e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KUM57960.1 - 1.8e-09 37.7 0.0 3.5e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KUM57960.1 - 5.4e-08 33.3 0.1 8.8e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal AMP-binding PF00501.23 KUM57961.1 - 2.2e-67 227.2 0.0 2.9e-67 226.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 KUM57961.1 - 8.8e-20 71.9 0.0 2.4e-19 70.4 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 KUM57961.1 - 4.1e-08 33.3 0.0 9.6e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 KUM57961.1 - 5e-05 23.2 0.2 0.00016 21.6 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM57961.1 - 0.0043 16.8 0.0 0.02 14.6 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family AMP-binding_C PF13193.1 KUM57961.1 - 0.027 15.4 0.4 0.072 14.0 0.3 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain AKAP7_RIRII_bdg PF10470.4 KUM57961.1 - 0.15 11.9 0.1 0.38 10.6 0.1 1.6 1 0 0 1 1 1 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein AMP-binding_C_2 PF14535.1 KUM57961.1 - 0.16 12.0 0.1 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Methyltransf_2 PF00891.13 KUM57962.1 - 4.5e-31 107.8 0.0 6.9e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 KUM57962.1 - 0.0002 21.1 0.1 0.00053 19.7 0.0 1.8 1 0 0 1 1 1 1 Dimerisation domain p450 PF00067.17 KUM57963.1 - 3.8e-28 98.2 0.0 5.9e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Dyp_perox PF04261.7 KUM57964.1 - 1.5e-11 43.6 0.1 4.8e-09 35.3 0.0 3.2 3 0 0 3 3 3 2 Dyp-type peroxidase family FAD_binding_3 PF01494.14 KUM57965.1 - 1.1e-13 51.0 0.0 1.6e-06 27.3 0.2 2.1 2 0 0 2 2 2 2 FAD binding domain SE PF08491.5 KUM57965.1 - 0.00035 19.4 0.0 0.39 9.4 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase GIDA PF01134.17 KUM57965.1 - 0.048 12.5 0.0 0.072 11.9 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF3106 PF11304.3 KUM57965.1 - 0.67 10.3 4.3 0.57 10.6 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Haem_oxygenas_2 PF14518.1 KUM57966.1 - 2.3e-10 40.5 0.1 5.5e-10 39.3 0.1 1.7 1 0 0 1 1 1 1 Iron-containing redox enzyme COesterase PF00135.23 KUM57967.1 - 4e-48 164.4 0.5 7.4e-48 163.5 0.3 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KUM57967.1 - 8.9e-05 22.1 0.0 0.0014 18.2 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold MFS_1 PF07690.11 KUM57968.1 - 1.3e-40 139.1 26.2 1.9e-40 138.6 18.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM57968.1 - 1.5e-11 43.5 27.3 6e-11 41.5 5.7 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter TRI12 PF06609.8 KUM57968.1 - 9.5e-08 30.6 2.6 9.5e-08 30.6 1.8 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4449 PF14613.1 KUM57969.1 - 5.9e-64 214.9 0.3 5.9e-64 214.9 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Ribosomal_L36e PF01158.13 KUM57969.1 - 0.055 13.4 1.2 0.21 11.5 0.3 2.2 1 1 1 2 2 2 0 Ribosomal protein L36e AIRC PF00731.15 KUM57970.1 - 9.1e-59 197.0 1.6 1.9e-58 195.9 1.1 1.6 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 KUM57970.1 - 1.7e-52 177.2 0.0 3.4e-52 176.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 KUM57970.1 - 1.8e-11 44.1 0.0 2.8e-10 40.2 0.0 2.3 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 KUM57970.1 - 2.2e-06 27.0 0.0 5.3e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.8 KUM57970.1 - 0.00011 21.7 0.0 0.0017 17.7 0.0 2.3 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_5 PF13549.1 KUM57970.1 - 0.017 14.3 0.0 0.033 13.3 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_Ter PF15632.1 KUM57970.1 - 0.022 13.5 0.0 0.16 10.6 0.0 2.2 3 0 0 3 3 3 0 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_M15_3 PF08291.6 KUM57970.1 - 0.036 13.8 0.1 0.49 10.2 0.0 2.8 3 1 0 3 3 3 0 Peptidase M15 XdhC_C PF13478.1 KUM57970.1 - 0.053 13.8 0.0 0.16 12.2 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain 2-Hacid_dh_C PF02826.14 KUM57970.1 - 0.058 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CoA_binding_2 PF13380.1 KUM57970.1 - 0.1 12.8 0.4 23 5.2 0.0 3.5 2 1 1 3 3 3 0 CoA binding domain PPP4R2 PF09184.6 KUM57971.1 - 1.6e-10 41.0 0.0 1.6e-10 41.0 0.0 2.6 3 0 0 3 3 3 1 PPP4R2 HSF_DNA-bind PF00447.12 KUM57972.1 - 5.1e-38 129.4 0.4 9.8e-38 128.5 0.2 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 KUM57972.1 - 1.9e-21 76.1 0.0 3.7e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Clusterin PF01093.12 KUM57972.1 - 0.018 13.8 1.3 0.029 13.1 0.9 1.3 1 0 0 1 1 1 0 Clusterin SlyX PF04102.7 KUM57972.1 - 0.053 13.8 5.7 0.22 11.9 3.9 2.1 1 0 0 1 1 1 0 SlyX CENP-Q PF13094.1 KUM57972.1 - 0.088 12.8 5.9 0.049 13.6 2.7 1.6 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 KUM57972.1 - 0.14 11.7 2.2 0.22 11.0 1.5 1.2 1 0 0 1 1 1 0 IncA protein Redoxin PF08534.5 KUM57973.1 - 1e-26 93.2 0.0 1.2e-26 93.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KUM57973.1 - 1.4e-08 34.4 0.0 1.9e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family BolA PF01722.13 KUM57974.1 - 2.8e-22 78.4 0.0 5.6e-22 77.4 0.0 1.5 2 0 0 2 2 2 1 BolA-like protein Ribosomal_L13e PF01294.13 KUM57974.1 - 0.071 12.5 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L13e NIF3 PF01784.13 KUM57975.1 - 5.4e-57 193.1 0.0 6.8e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) ENTH PF01417.15 KUM57976.1 - 4.4e-47 159.0 0.0 8.3e-47 158.1 0.0 1.5 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 KUM57976.1 - 0.00089 18.0 0.0 0.0013 17.4 0.0 1.2 1 0 0 1 1 1 1 ANTH domain UIM PF02809.15 KUM57976.1 - 0.028 13.9 0.9 0.028 13.9 0.6 2.5 2 0 0 2 2 2 0 Ubiquitin interaction motif DUF4264 PF14084.1 KUM57976.1 - 0.031 13.6 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) Ank_2 PF12796.2 KUM57977.1 - 1.7e-39 134.0 0.6 3e-15 56.3 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KUM57977.1 - 1.3e-36 124.3 9.6 9.9e-10 38.6 0.0 4.6 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 KUM57977.1 - 1.3e-36 122.5 4.2 1.9e-08 33.6 0.0 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.1 KUM57977.1 - 1.1e-31 105.6 0.7 6.7e-06 25.8 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 KUM57977.1 - 5.5e-29 99.5 1.9 5.3e-10 39.2 0.1 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) DUF3447 PF11929.3 KUM57977.1 - 0.037 13.8 0.0 0.5 10.2 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3447) Shigella_OspC PF06128.6 KUM57977.1 - 0.13 11.7 0.3 2.1 7.7 0.2 2.7 1 1 1 2 2 2 0 Shigella flexneri OspC protein DUF3619 PF12279.3 KUM57980.1 - 0.014 15.4 0.9 0.023 14.7 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) MAT1 PF06391.8 KUM57980.1 - 0.11 12.0 4.2 0.16 11.5 2.9 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 DUF947 PF06102.7 KUM57980.1 - 0.22 11.3 2.9 0.31 10.8 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF947) OmpH PF03938.9 KUM57980.1 - 0.88 9.4 6.7 1.3 8.9 4.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Wbp11 PF09429.5 KUM57980.1 - 8.9 6.3 11.5 0.43 10.5 4.0 1.8 2 1 0 2 2 2 0 WW domain binding protein 11 Cyanate_lyase PF02560.9 KUM57981.1 - 7.1e-32 108.7 0.0 1.2e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.1 KUM57981.1 - 0.14 12.3 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Carb_kinase PF01256.12 KUM57982.1 - 0.047 12.9 1.2 0.082 12.1 0.6 1.5 1 1 1 2 2 2 0 Carbohydrate kinase Inhibitor_I34 PF10466.4 KUM57982.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 1 0 1 1 1 0 Saccharopepsin inhibitor I34 zf-C2H2_6 PF13912.1 KUM57983.1 - 0.021 14.7 8.5 0.039 13.8 0.0 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KUM57983.1 - 0.023 15.0 28.7 0.072 13.4 0.0 6.2 6 0 0 6 6 6 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KUM57983.1 - 0.023 14.9 25.3 0.14 12.5 0.1 6.5 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KUM57983.1 - 4 7.6 26.1 0.4 10.8 0.2 4.0 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) SR-25 PF10500.4 KUM57984.1 - 2 7.8 28.0 0.69 9.3 7.7 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DNA_pol_B PF00136.16 KUM57985.1 - 2.6e-145 484.7 2.5 4.1e-145 484.1 1.7 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KUM57985.1 - 2.1e-81 273.3 0.0 3.9e-81 272.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KUM57985.1 - 6.5e-24 83.7 6.5 1.5e-23 82.5 4.5 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 KUM57985.1 - 0.00078 19.2 0.6 0.0041 16.9 0.4 2.3 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 KUM57985.1 - 0.011 15.3 0.1 0.025 14.1 0.1 1.6 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Pkinase PF00069.20 KUM57986.1 - 2.9e-37 128.2 0.0 4.4e-23 81.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KUM57986.1 - 4.3e-17 62.0 0.0 4.4e-07 29.2 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Acyl-CoA_dh_1 PF00441.19 KUM57987.1 - 3.7e-31 108.2 0.1 5.9e-31 107.6 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KUM57987.1 - 1.3e-21 75.8 0.6 3.1e-21 74.6 0.4 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KUM57987.1 - 1.6e-21 76.9 0.0 3.9e-21 75.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KUM57987.1 - 0.00025 21.2 0.0 0.00048 20.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CrtC PF07143.6 KUM57988.1 - 1.9e-09 37.2 0.2 6.3e-09 35.5 0.1 1.7 1 1 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) VIT1 PF01988.14 KUM57989.1 - 0.041 13.3 0.2 0.12 11.7 0.1 1.8 1 1 1 2 2 2 0 VIT family DUF1237 PF06824.6 KUM57990.1 - 1e-180 600.9 0.1 1.1e-180 600.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) C2 PF00168.25 KUM57990.1 - 0.021 14.6 0.0 0.058 13.2 0.0 1.8 1 0 0 1 1 1 0 C2 domain CDC27 PF09507.5 KUM57991.1 - 2.5e-82 277.4 30.9 2.8e-82 277.2 21.4 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 MRP-S26 PF14943.1 KUM57991.1 - 0.2 11.1 6.2 0.044 13.3 1.9 1.6 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 SAP PF02037.22 KUM57992.1 - 4.3e-05 22.8 0.0 7.2e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 SAP domain Med25_NR-box PF11244.3 KUM57992.1 - 0.099 13.1 0.7 0.21 12.0 0.1 1.8 2 0 0 2 2 2 0 Mediator complex subunit 25 C-terminal NR box-containing Snf7 PF03357.16 KUM57993.1 - 6.5e-17 61.4 13.3 9.2e-17 60.9 8.9 1.5 1 1 0 1 1 1 1 Snf7 DUF3461 PF11944.3 KUM57993.1 - 0.17 11.7 3.1 0.12 12.1 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3461) MbeD_MobD PF04899.7 KUM57993.1 - 0.26 11.2 3.0 0.32 10.9 0.0 2.6 2 0 0 2 2 2 0 MbeD/MobD like Abhydrolase_6 PF12697.2 KUM57995.1 - 1.1e-14 54.8 0.6 1.3e-14 54.6 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family MBF1 PF08523.5 KUM57995.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Multiprotein bridging factor 1 Methyltransf_2 PF00891.13 KUM57996.1 - 3.1e-29 101.8 0.0 8.4e-29 100.4 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 KUM57996.1 - 0.00083 19.1 0.3 0.004 16.9 0.2 2.3 1 0 0 1 1 1 1 Dimerisation domain HTH_24 PF13412.1 KUM57996.1 - 0.0019 17.5 0.0 0.0043 16.4 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Methyltransf_23 PF13489.1 KUM57996.1 - 0.0025 17.5 0.0 0.0047 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain HTH_IclR PF09339.5 KUM57996.1 - 0.0053 16.3 0.4 0.018 14.5 0.0 2.1 2 0 0 2 2 2 1 IclR helix-turn-helix domain Rrf2 PF02082.15 KUM57996.1 - 0.009 16.1 0.1 0.044 13.8 0.0 2.1 2 0 0 2 2 2 1 Transcriptional regulator MarR_2 PF12802.2 KUM57996.1 - 0.031 13.9 0.1 0.086 12.5 0.0 1.7 1 0 0 1 1 1 0 MarR family HTH_5 PF01022.15 KUM57996.1 - 0.036 13.7 0.0 0.084 12.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Methyltransf_4 PF02390.12 KUM57996.1 - 0.092 11.7 0.0 0.41 9.6 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase HTH_Crp_2 PF13545.1 KUM57996.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Epiglycanin_C PF14654.1 KUM57997.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Trypan_PARP PF05887.6 KUM57998.1 - 0.00068 19.4 21.7 0.0012 18.6 15.0 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) RSF PF14876.1 KUM57998.1 - 0.14 10.8 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Respiratory growth transcriptional regulator Aldo_ket_red PF00248.16 KUM58000.1 - 1.2e-40 139.0 0.0 3.8e-34 117.7 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Seadorna_Vp10 PF07322.6 KUM58000.1 - 0.096 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus Vp10 PDZ_assoc PF10600.4 KUM58000.1 - 0.11 12.7 1.3 4.7 7.5 0.0 3.2 3 0 0 3 3 3 0 PDZ-associated domain of NMDA receptors PUA PF01472.15 KUM58000.1 - 0.13 11.9 0.1 0.28 10.9 0.1 1.5 1 0 0 1 1 1 0 PUA domain Polysacc_synt_4 PF04669.8 KUM58001.1 - 1.2e-20 73.7 2.8 1.1e-19 70.6 2.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis ABC_membrane PF00664.18 KUM58002.1 - 5.3e-71 239.2 28.6 3.2e-36 125.1 8.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KUM58002.1 - 1.1e-60 203.9 0.0 6.8e-29 100.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KUM58002.1 - 1.7e-18 66.6 1.1 3.2e-08 33.0 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KUM58002.1 - 1.5e-14 54.7 0.0 0.0034 17.4 0.0 4.4 3 1 0 3 3 3 3 AAA domain AAA_29 PF13555.1 KUM58002.1 - 2e-09 36.8 0.4 0.0022 17.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KUM58002.1 - 2.3e-08 34.8 0.0 0.0056 17.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 KUM58002.1 - 6.2e-08 32.8 1.2 0.0048 17.0 0.0 4.0 3 2 0 3 3 2 2 AAA domain AAA_25 PF13481.1 KUM58002.1 - 3.4e-07 29.8 0.1 0.1 11.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_10 PF12846.2 KUM58002.1 - 2e-06 27.5 2.2 0.0071 15.8 0.0 3.9 4 0 0 4 4 4 2 AAA-like domain AAA_16 PF13191.1 KUM58002.1 - 4e-06 26.9 0.8 0.12 12.3 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.1 KUM58002.1 - 5.6e-06 26.6 0.1 0.045 14.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KUM58002.1 - 1.5e-05 24.2 0.2 0.24 10.5 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_13 PF13166.1 KUM58002.1 - 3.5e-05 22.4 0.3 1.1 7.6 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.1 KUM58002.1 - 0.00022 21.1 0.0 0.4 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 KUM58002.1 - 0.00033 20.5 0.3 0.82 9.4 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function DUF87 SbcCD_C PF13558.1 KUM58002.1 - 0.00039 20.2 0.0 1.4 8.8 0.0 3.3 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DUF3987 PF13148.1 KUM58002.1 - 0.00045 18.8 0.1 0.7 8.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) ABC_ATPase PF09818.4 KUM58002.1 - 0.00047 18.8 2.4 0.051 12.1 0.1 3.2 3 1 0 3 3 3 1 Predicted ATPase of the ABC class AAA_15 PF13175.1 KUM58002.1 - 0.0005 19.2 2.3 3.3 6.6 0.0 4.5 5 0 0 5 5 5 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 KUM58002.1 - 0.00067 19.1 0.0 1.4 8.3 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_5 PF07728.9 KUM58002.1 - 0.00074 19.2 0.2 2 8.1 0.1 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) MobB PF03205.9 KUM58002.1 - 0.0013 18.4 0.1 1.4 8.6 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 KUM58002.1 - 0.0039 17.4 0.0 0.16 12.1 0.0 3.4 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 KUM58002.1 - 0.0048 17.2 0.3 0.59 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KUM58002.1 - 0.0054 16.8 0.1 1.4 9.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.7 KUM58002.1 - 0.022 14.4 1.0 2 8.0 0.0 2.8 3 0 0 3 3 2 0 NACHT domain APS_kinase PF01583.15 KUM58002.1 - 0.023 14.3 0.1 7.6 6.1 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase MMR_HSR1 PF01926.18 KUM58002.1 - 0.024 14.5 2.2 3 7.8 0.0 3.1 3 1 0 3 3 2 0 50S ribosome-binding GTPase AAA_19 PF13245.1 KUM58002.1 - 0.055 13.2 0.1 2.4 7.9 0.1 2.8 2 0 0 2 2 2 0 Part of AAA domain CbiA PF01656.18 KUM58002.1 - 0.078 12.3 1.4 2 7.7 0.1 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Septin PF00735.13 KUM58002.1 - 0.08 11.9 0.2 0.72 8.8 0.0 2.1 2 0 0 2 2 2 0 Septin Miro PF08477.8 KUM58002.1 - 0.11 12.9 0.2 8.8 6.8 0.0 3.2 3 0 0 3 3 2 0 Miro-like protein G-alpha PF00503.15 KUM58002.1 - 0.2 10.3 0.2 5 5.7 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit KaiC PF06745.8 KUM58002.1 - 1.6 7.7 7.8 4 6.4 0.0 3.7 5 0 0 5 5 4 0 KaiC Rif1_N PF12231.3 KUM58003.1 - 2.4e-139 464.4 0.2 3.7e-139 463.8 0.1 1.3 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Ric8 PF10165.4 KUM58004.1 - 3e-127 425.1 0.0 3.9e-127 424.7 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Cnd3 PF12719.2 KUM58004.1 - 0.021 13.8 0.0 0.046 12.6 0.0 1.6 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain KOW PF00467.24 KUM58005.1 - 5.5e-06 25.8 0.4 1.5e-05 24.4 0.3 1.7 1 0 0 1 1 1 1 KOW motif Synaptobrevin PF00957.16 KUM58008.1 - 6.7e-32 108.9 0.0 9e-32 108.5 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KUM58008.1 - 2.5e-23 81.4 0.0 4.1e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF879 PF05947.7 KUM58008.1 - 0.085 11.1 0.0 0.11 10.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF879) DUF2628 PF10947.3 KUM58008.1 - 0.22 11.3 1.8 0.44 10.3 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) ODV-E18 PF10717.4 KUM58008.1 - 0.48 9.8 2.1 0.76 9.2 0.1 2.1 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 CorA PF01544.13 KUM58009.1 - 7.1e-05 21.9 10.9 0.00024 20.2 7.5 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2749 PF10907.3 KUM58009.1 - 0.011 15.6 0.0 0.43 10.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) HTH_16 PF12645.2 KUM58009.1 - 0.029 14.3 3.3 0.11 12.4 0.1 2.9 2 1 1 3 3 3 0 Helix-turn-helix domain WBP-1 PF11669.3 KUM58009.1 - 6 6.9 5.9 6.4 6.9 0.7 3.0 2 1 1 3 3 3 0 WW domain-binding protein 1 MAS20 PF02064.10 KUM58011.1 - 3e-20 72.3 0.1 1.2e-19 70.3 0.1 1.7 1 1 0 1 1 1 1 MAS20 protein import receptor PAXIP1_C PF15364.1 KUM58011.1 - 0.013 15.4 1.4 0.29 11.0 0.4 2.1 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein FlgM PF04316.8 KUM58011.1 - 0.1 12.5 0.9 0.18 11.8 0.6 1.4 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM Toxin_39 PF15500.1 KUM58011.1 - 0.12 12.5 1.3 0.19 11.8 0.9 1.3 1 0 0 1 1 1 0 Putative RNase-like toxin CPSase_L_D2 PF02786.12 KUM58012.1 - 6.1e-114 378.5 0.1 1.2e-83 279.6 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.23 KUM58012.1 - 1.2e-45 155.2 0.0 5.6e-45 153.1 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 KUM58012.1 - 1.8e-45 153.6 0.0 4.7e-45 152.3 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.16 KUM58012.1 - 1.7e-42 144.4 0.0 3.6e-42 143.3 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 KUM58012.1 - 4.2e-41 139.4 0.0 3.7e-19 68.8 0.0 2.9 3 0 0 3 3 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 KUM58012.1 - 2.7e-39 133.7 0.0 6.1e-39 132.5 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.19 KUM58012.1 - 4.9e-33 114.2 0.0 1.2e-32 112.9 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 KUM58012.1 - 2.2e-32 112.3 0.1 5.2e-20 71.9 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 KUM58012.1 - 5.7e-21 74.2 0.0 2.8e-20 72.0 0.0 2.3 1 0 0 1 1 1 1 MGS-like domain ATPgrasp_Ter PF15632.1 KUM58012.1 - 1.9e-20 72.9 0.0 5e-09 35.3 0.0 4.0 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KUM58012.1 - 1.2e-15 57.4 0.2 1.6e-07 30.9 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KUM58012.1 - 5.6e-14 51.8 0.0 8.4e-07 28.4 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 KUM58012.1 - 1.9e-07 30.7 0.1 3e-06 26.8 0.1 2.3 1 1 0 1 1 1 1 Peptidase C26 RimK PF08443.6 KUM58012.1 - 1e-05 25.0 0.0 0.0046 16.4 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KUM58012.1 - 4.2e-05 23.4 0.3 0.5 10.2 0.0 3.0 2 0 0 2 2 2 2 ATP-grasp domain AMP-binding PF00501.23 KUM58013.1 - 2.2e-77 260.2 0.0 2.8e-77 259.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MFS_1 PF07690.11 KUM58013.1 - 5.4e-27 94.4 17.9 9.3e-27 93.6 12.4 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily AMP-binding_C PF13193.1 KUM58013.1 - 1.2e-09 38.9 0.4 3.9e-09 37.3 0.3 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Vps51 PF08700.6 KUM58015.1 - 2.1e-18 65.9 1.5 5.3e-18 64.6 1.0 1.6 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 KUM58015.1 - 0.013 15.3 0.1 0.044 13.6 0.0 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Sec63 PF02889.11 KUM58016.1 - 1e-145 484.8 0.0 6.8e-96 321.1 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KUM58016.1 - 1.1e-54 184.4 0.3 1.2e-28 99.7 0.5 3.4 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM58016.1 - 1.8e-18 66.1 0.0 8.1e-08 32.0 0.0 3.3 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 KUM58016.1 - 1.1e-16 61.2 0.0 3.2e-07 30.3 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KUM58016.1 - 2.8e-09 37.2 0.0 0.0023 18.0 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KUM58016.1 - 1.4e-05 24.7 0.1 0.016 14.9 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain SNF2_N PF00176.18 KUM58016.1 - 4.2e-05 22.4 0.7 0.046 12.5 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain IstB_IS21 PF01695.12 KUM58016.1 - 0.0061 16.0 0.4 2.7 7.3 0.0 3.7 4 0 0 4 4 4 1 IstB-like ATP binding protein PhoH PF02562.11 KUM58016.1 - 0.0099 15.1 0.0 4.4 6.4 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein FtsK_SpoIIIE PF01580.13 KUM58016.1 - 0.017 14.6 0.1 3.3 7.1 0.1 3.2 3 1 0 3 3 3 0 FtsK/SpoIIIE family AAA_10 PF12846.2 KUM58016.1 - 0.038 13.4 0.0 7.8 5.8 0.0 3.5 4 0 0 4 4 4 0 AAA-like domain Synaptobrevin PF00957.16 KUM58017.1 - 5.7e-15 54.6 0.7 9.9e-15 53.9 0.5 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KUM58017.1 - 2.5e-14 52.6 0.0 4.3e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Tbf5 PF06331.7 KUM58017.1 - 0.0089 15.7 0.7 0.017 14.9 0.5 1.4 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 FAD_binding_3 PF01494.14 KUM58018.1 - 3.2e-12 46.2 0.0 1e-10 41.2 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 KUM58018.1 - 0.00059 19.6 0.0 0.014 15.2 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 KUM58018.1 - 0.0007 18.5 0.0 0.0013 17.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KUM58018.1 - 0.0015 18.5 0.0 0.0045 16.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KUM58018.1 - 0.025 14.4 0.0 0.058 13.2 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KUM58018.1 - 0.047 12.6 0.0 3.3 6.5 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein DUF3666 PF12408.3 KUM58018.1 - 0.42 9.7 1.8 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Ribose-5-phosphate isomerase YL1_C PF08265.6 KUM58019.1 - 4.6e-16 58.0 0.4 1.2e-15 56.7 0.1 1.8 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Profilin PF00235.14 KUM58020.1 - 1.6e-35 121.8 0.1 2e-35 121.5 0.1 1.1 1 0 0 1 1 1 1 Profilin AA_permease PF00324.16 KUM58022.1 - 8.3e-102 340.9 32.2 1.1e-101 340.5 22.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KUM58022.1 - 1.5e-27 96.2 34.9 2e-27 95.7 24.2 1.1 1 0 0 1 1 1 1 Amino acid permease HDOD PF08668.7 KUM58022.1 - 0.097 11.9 0.6 0.16 11.2 0.4 1.3 1 0 0 1 1 1 0 HDOD domain HPP PF04982.8 KUM58023.1 - 1.2e-40 138.1 7.1 1.2e-40 138.1 4.9 1.9 2 0 0 2 2 2 1 HPP family Acyl_transf_3 PF01757.17 KUM58023.1 - 0.017 13.9 7.8 0.021 13.6 5.4 1.0 1 0 0 1 1 1 0 Acyltransferase family DUF4231 PF14015.1 KUM58023.1 - 0.25 11.3 0.1 0.25 11.3 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) EmrE PF13536.1 KUM58023.1 - 1.7 8.8 12.5 4.4 7.5 4.5 2.7 2 1 0 2 2 2 0 Multidrug resistance efflux transporter Got1 PF04178.7 KUM58025.1 - 6.5e-08 32.6 0.7 7.4e-08 32.5 0.5 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family Fungal_trans PF04082.13 KUM58026.1 - 4.9e-11 42.0 0.0 8.3e-11 41.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cupin_2 PF07883.6 KUM58027.1 - 4.7e-10 38.8 0.0 6.5e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Cupin domain CDO_I PF05995.7 KUM58027.1 - 0.015 14.4 0.0 0.021 13.9 0.0 1.3 1 1 0 1 1 1 0 Cysteine dioxygenase type I Cupin_1 PF00190.17 KUM58027.1 - 0.022 14.2 0.0 0.036 13.5 0.0 1.2 1 1 0 1 1 1 0 Cupin DUF4437 PF14499.1 KUM58027.1 - 0.04 12.8 0.0 0.055 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) DASH_Dad4 PF08650.5 KUM58028.1 - 8.4e-28 96.0 6.9 9.2e-28 95.9 4.8 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 GM_CSF PF01109.12 KUM58028.1 - 0.045 13.6 0.3 0.051 13.5 0.2 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor DUF2443 PF10398.4 KUM58028.1 - 0.1 12.4 0.5 0.16 11.8 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2443) DASH_Dad1 PF08649.5 KUM58028.1 - 0.23 11.1 2.3 0.29 10.8 1.6 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad1 Actin PF00022.14 KUM58029.1 - 2.6e-54 184.1 0.0 3.8e-30 104.5 0.0 2.2 2 0 0 2 2 2 2 Actin Acetyltransf_3 PF13302.1 KUM58030.1 - 6.5e-33 113.8 0.0 8e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KUM58030.1 - 0.039 13.9 0.0 0.16 12.0 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Lipl32 PF12103.3 KUM58030.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 1 0 1 1 1 0 Surface lipoprotein of Spirochaetales order V_ATPase_I PF01496.14 KUM58031.1 - 5.9e-299 993.2 0.1 6.7e-299 993.1 0.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF1515 PF07439.6 KUM58031.1 - 0.027 14.2 0.1 0.076 12.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) CheZ PF04344.8 KUM58031.1 - 0.14 11.8 1.0 0.62 9.6 0.1 2.3 2 1 0 2 2 2 0 Chemotaxis phosphatase, CheZ BUD22 PF09073.5 KUM58032.1 - 0.021 13.9 19.5 0.022 13.8 13.5 1.1 1 0 0 1 1 1 0 BUD22 RNA_pol_3_Rpc31 PF11705.3 KUM58032.1 - 0.13 12.1 24.5 0.18 11.7 17.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DDHD PF02862.12 KUM58032.1 - 0.31 10.7 7.5 0.37 10.5 5.2 1.2 1 0 0 1 1 1 0 DDHD domain DUF1510 PF07423.6 KUM58032.1 - 0.37 10.1 21.5 0.41 9.9 14.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) G_glu_transpept PF01019.16 KUM58032.1 - 0.52 8.7 2.7 0.65 8.4 1.9 1.0 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase CobT PF06213.7 KUM58032.1 - 1.4 7.9 24.7 1.5 7.9 17.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RP-C_C PF11800.3 KUM58032.1 - 1.5 8.4 8.8 1.9 8.1 6.1 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF2201_N PF13203.1 KUM58032.1 - 1.5 7.8 6.8 1.4 8.0 4.7 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain RR_TM4-6 PF06459.7 KUM58032.1 - 1.9 8.2 16.4 2.2 8.1 11.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.17 KUM58032.1 - 2.3 7.1 5.9 2.2 7.1 4.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Pilt PF15453.1 KUM58032.1 - 2.4 7.7 10.1 2.4 7.7 7.0 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Spore_coat_CotO PF14153.1 KUM58032.1 - 3.2 7.1 21.9 4.6 6.6 15.2 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Hid1 PF12722.2 KUM58032.1 - 3.2 5.2 6.7 3.6 5.1 4.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1682 PF07946.9 KUM58032.1 - 5.4 5.7 17.6 6.4 5.5 12.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PH_6 PF15406.1 KUM58033.1 - 9.2e-38 128.7 4.1 9.2e-38 128.7 2.8 3.5 3 1 1 4 4 4 1 Pleckstrin homology domain PH PF00169.24 KUM58033.1 - 0.001 19.2 0.0 0.0028 17.8 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_4 PF15404.1 KUM58033.1 - 0.26 10.8 0.0 0.26 10.8 0.0 3.4 3 1 0 3 3 3 0 Pleckstrin homology domain Ceramidase PF05875.7 KUM58034.1 - 1.3e-57 194.9 8.1 2.2e-57 194.2 5.6 1.3 1 1 0 1 1 1 1 Ceramidase OPT PF03169.10 KUM58034.1 - 0.0043 15.5 1.5 0.034 12.5 0.0 2.1 1 1 1 2 2 2 2 OPT oligopeptide transporter protein Asn_synthase PF00733.16 KUM58035.1 - 7.4e-50 169.8 0.0 1e-49 169.3 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KUM58035.1 - 4.1e-07 29.7 0.0 2.2e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KUM58035.1 - 0.00011 22.2 0.0 0.00024 21.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KUM58035.1 - 0.00085 18.5 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 Aluminium induced protein bZIP_1 PF00170.16 KUM58036.1 - 7.4e-06 25.8 5.6 1.3e-05 25.0 3.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KUM58036.1 - 0.00023 20.8 8.0 0.00046 19.9 5.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Fib_alpha PF08702.5 KUM58036.1 - 0.064 13.3 0.3 0.12 12.5 0.2 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family SlyX PF04102.7 KUM58036.1 - 0.12 12.7 1.0 0.27 11.6 0.7 1.5 1 0 0 1 1 1 0 SlyX Bap31 PF05529.7 KUM58036.1 - 0.63 9.4 3.7 0.97 8.8 2.6 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Abhydrolase_6 PF12697.2 KUM58037.1 - 5.3e-27 95.1 0.8 1.4e-26 93.8 0.6 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM58037.1 - 9.2e-06 25.4 0.0 2.1e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM58037.1 - 8.5e-05 22.2 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 KUM58037.1 - 0.0055 16.3 0.2 0.02 14.5 0.0 1.9 3 0 0 3 3 3 1 PGAP1-like protein VPS9 PF02204.13 KUM58038.1 - 6.4e-31 106.4 0.0 1.2e-30 105.5 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 KUM58038.1 - 2.8e-09 36.2 0.2 4.3e-08 32.4 0.0 2.3 2 0 0 2 2 2 1 CUE domain Mito_carr PF00153.22 KUM58039.1 - 1.7e-53 178.3 3.5 8.6e-19 67.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Apc15p PF05841.6 KUM58041.1 - 0.24 12.1 8.7 0.28 11.9 6.1 1.1 1 0 0 1 1 1 0 Apc15p protein Secretin_N_2 PF07655.8 KUM58041.1 - 0.62 10.4 9.4 0.75 10.2 6.5 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain Spore_coat_CotO PF14153.1 KUM58041.1 - 0.7 9.3 3.3 0.78 9.1 2.3 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Endostatin PF06482.6 KUM58041.1 - 0.98 8.7 3.7 1 8.6 2.6 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin MRI PF15325.1 KUM58041.1 - 1.2 10.0 4.6 1.5 9.8 3.2 1.2 1 0 0 1 1 1 0 Modulator of retrovirus infection Menin PF05053.8 KUM58041.1 - 4.1 5.4 8.3 4.7 5.2 5.8 1.0 1 0 0 1 1 1 0 Menin MFS_1 PF07690.11 KUM58042.1 - 7e-18 64.4 45.5 3e-17 62.3 30.7 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily PetG PF02529.10 KUM58042.1 - 0.093 12.2 4.0 0.92 9.0 0.0 2.7 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 ketoacyl-synt PF00109.21 KUM58043.1 - 4e-70 236.1 0.1 7.1e-70 235.3 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KUM58043.1 - 1.4e-55 188.8 0.0 2.3e-55 188.1 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KUM58043.1 - 1.6e-55 187.5 0.4 4.5e-55 186.1 0.2 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 KUM58043.1 - 5.6e-54 183.3 0.0 9.5e-54 182.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KUM58043.1 - 1.2e-44 152.1 0.2 3e-44 150.8 0.1 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KUM58043.1 - 2.6e-33 114.3 0.1 1.2e-32 112.2 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 KUM58043.1 - 2.2e-06 26.8 0.1 6.5e-06 25.3 0.1 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 KUM58043.1 - 0.0019 17.8 1.5 0.011 15.3 1.0 2.5 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GMC_oxred_N PF00732.14 KUM58044.1 - 3e-59 200.5 0.0 3.9e-59 200.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KUM58044.1 - 1.4e-36 125.9 0.0 3e-36 124.8 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KUM58044.1 - 1e-07 31.2 0.6 0.0003 19.8 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KUM58044.1 - 1.4e-07 30.7 0.1 0.00081 18.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KUM58044.1 - 8.7e-07 28.8 0.4 5.1e-06 26.4 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KUM58044.1 - 2.7e-05 24.3 0.2 0.069 13.2 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KUM58044.1 - 5.2e-05 23.2 0.0 0.2 11.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KUM58044.1 - 0.0041 16.2 0.0 0.0099 14.9 0.0 1.6 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KUM58044.1 - 0.0098 14.4 0.2 0.063 11.7 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 KUM58044.1 - 0.01 15.6 0.5 0.4 10.4 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KUM58044.1 - 0.02 13.8 0.2 0.04 12.8 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 KUM58044.1 - 0.052 12.5 0.4 0.11 11.5 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 KUM58044.1 - 0.062 12.1 0.1 2.9 6.6 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Amidohydro_4 PF13147.1 KUM58045.1 - 3.9e-25 89.4 0.0 5.5e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KUM58045.1 - 7.1e-15 54.5 0.6 1.4e-14 53.6 0.4 1.5 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KUM58045.1 - 1.5e-12 47.8 0.0 1.9e-08 34.3 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 KUM58045.1 - 0.00037 19.8 0.0 0.15 11.2 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Urease_alpha PF00449.15 KUM58045.1 - 0.049 13.7 0.1 0.099 12.7 0.1 1.4 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain Zn_clus PF00172.13 KUM58046.1 - 1.7e-06 27.8 9.9 3.7e-06 26.7 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KUM58046.1 - 0.00018 20.2 0.1 0.00021 20.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain LON PF02190.11 KUM58047.1 - 2.2e-24 86.2 0.0 5.3e-24 85.0 0.0 1.6 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 KUM58047.1 - 2.2e-12 46.7 19.0 5.7e-08 32.6 6.6 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KUM58047.1 - 8e-11 41.6 16.0 1.6e-06 27.8 4.2 2.7 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KUM58047.1 - 1.3e-10 40.9 20.5 5.9e-08 32.4 6.9 2.4 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.1 KUM58047.1 - 2.6e-10 39.8 16.9 7.7e-07 28.7 5.2 2.4 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KUM58047.1 - 9.5e-10 37.9 17.6 4.8e-09 35.7 4.7 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KUM58047.1 - 2.3e-08 33.5 16.6 5.2e-07 29.2 5.9 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KUM58047.1 - 1.7e-07 30.8 12.3 5e-06 26.1 1.0 3.5 2 1 1 3 3 3 2 RING-type zinc-finger U-box PF04564.10 KUM58047.1 - 0.002 18.0 0.1 0.0075 16.2 0.0 1.9 2 0 0 2 2 2 1 U-box domain zf-RING_4 PF14570.1 KUM58047.1 - 0.0022 17.5 7.9 0.0061 16.1 3.7 2.5 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 KUM58047.1 - 0.0048 16.9 4.0 0.02 15.0 2.6 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger Prok-RING_4 PF14447.1 KUM58047.1 - 0.077 12.5 11.9 0.26 10.8 2.2 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-P11 PF03854.9 KUM58047.1 - 0.13 11.7 9.5 0.027 13.9 2.8 2.5 2 0 0 2 2 2 0 P-11 zinc finger zf-C2HC_2 PF13913.1 KUM58047.1 - 0.23 11.1 4.4 2.4 7.9 0.4 2.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DZR PF12773.2 KUM58047.1 - 3.9 7.3 13.4 7.1 6.5 2.9 2.9 2 1 1 3 3 3 0 Double zinc ribbon zf-RING_6 PF14835.1 KUM58047.1 - 5.1 6.9 17.8 0.11 12.2 1.8 2.7 3 0 0 3 3 2 0 zf-RING of BARD1-type protein Rad9 PF04139.8 KUM58048.1 - 7.4e-59 198.9 1.6 8.8e-59 198.6 1.1 1.1 1 0 0 1 1 1 1 Rad9 RCC1 PF00415.13 KUM58049.1 - 3.9e-34 116.6 10.6 8e-08 32.3 0.0 7.4 7 3 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KUM58049.1 - 1.4e-19 69.1 25.6 1.3e-06 27.8 0.6 6.4 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat PET PF06297.9 KUM58049.1 - 0.13 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 PET Domain Sugar_tr PF00083.19 KUM58050.1 - 2.5e-23 82.4 24.9 2.4e-21 75.8 17.3 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Tautomerase PF01361.16 KUM58052.1 - 0.077 12.6 0.0 2.4 7.8 0.0 2.2 1 1 0 1 1 1 0 Tautomerase enzyme DUF1318 PF07027.7 KUM58053.1 - 0.013 15.6 0.2 0.02 15.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1318) MMS1_N PF10433.4 KUM58054.1 - 4e-89 299.0 0.0 6.5e-89 298.3 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 KUM58054.1 - 3.1e-77 259.8 0.0 9e-74 248.4 0.0 3.6 4 0 0 4 4 4 3 CPSF A subunit region FAD_binding_1 PF00667.15 KUM58055.1 - 8.4e-61 205.1 0.0 1.3e-60 204.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KUM58055.1 - 1.5e-34 119.0 1.9 2.9e-34 118.1 1.3 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KUM58055.1 - 8.2e-22 77.8 0.1 8.9e-21 74.5 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KUM58055.1 - 0.013 15.5 0.1 0.053 13.5 0.0 2.1 2 0 0 2 2 2 0 Flavodoxin domain TatD_DNase PF01026.16 KUM58056.1 - 6.6e-45 153.2 0.0 7.6e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase MARVEL PF01284.18 KUM58059.1 - 0.039 13.7 14.6 0.24 11.1 10.6 1.8 1 1 1 2 2 2 0 Membrane-associating domain SUR7 PF06687.7 KUM58059.1 - 0.1 12.1 4.1 2.4 7.6 0.0 2.2 2 0 0 2 2 2 0 SUR7/PalI family PGA2 PF07543.7 KUM58060.1 - 8.5e-33 113.1 3.3 1.1e-32 112.7 2.3 1.1 1 0 0 1 1 1 1 Protein trafficking PGA2 NAD_binding_11 PF14833.1 KUM58061.1 - 2.1e-32 111.7 0.0 4e-32 110.8 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 KUM58061.1 - 5.2e-32 110.9 0.2 8e-32 110.3 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 KUM58061.1 - 0.0079 15.3 0.0 0.014 14.5 0.0 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KUM58061.1 - 0.017 15.5 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TGS PF02824.16 KUM58061.1 - 0.033 14.0 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 TGS domain MOR2-PAG1_N PF14222.1 KUM58062.1 - 1.3e-222 740.3 0.0 2.3e-222 739.5 0.0 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 KUM58062.1 - 3.5e-97 325.2 0.0 1.8e-96 322.9 0.0 2.2 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 KUM58062.1 - 6.6e-36 123.3 11.8 2.2e-12 45.4 0.2 3.8 2 1 1 3 3 3 3 Cell morphogenesis central region Bac_rhamnosid PF05592.6 KUM58063.1 - 1.8e-170 567.5 0.0 2.3e-170 567.1 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 KUM58063.1 - 1.7e-52 177.4 0.0 2.7e-52 176.7 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Sugar_tr PF00083.19 KUM58064.1 - 7.8e-81 271.9 17.3 9.5e-81 271.6 12.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM58064.1 - 3.3e-28 98.4 20.8 4.3e-28 98.0 14.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KUM58064.1 - 0.0086 15.8 7.0 0.43 10.3 0.0 4.0 4 0 0 4 4 4 2 MFS_1 like family Fungal_trans PF04082.13 KUM58065.1 - 5.2e-06 25.5 0.2 8.7e-06 24.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Alpha-L-AF_C PF06964.7 KUM58066.1 - 5.3e-31 107.7 1.6 1.1e-30 106.7 1.1 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Cpn60_TCP1 PF00118.19 KUM58067.1 - 8e-163 542.5 0.1 9.1e-163 542.3 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1168 PF06658.7 KUM58068.1 - 1.1e-42 144.9 8.9 1.6e-42 144.3 6.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) RNase_H2-Ydr279 PF09468.5 KUM58068.1 - 0.02 14.1 5.9 0.023 13.9 4.1 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) RNA_polI_A34 PF08208.6 KUM58068.1 - 0.19 11.3 10.4 0.23 11.1 7.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 YqfQ PF14181.1 KUM58068.1 - 0.64 10.0 6.0 1.2 9.1 4.1 1.6 1 0 0 1 1 1 0 YqfQ-like protein Peptidase_S49_N PF08496.5 KUM58068.1 - 1.4 8.7 5.8 2 8.1 4.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Med19 PF10278.4 KUM58068.1 - 1.8 8.2 13.8 2.7 7.6 9.5 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 NPR3 PF03666.8 KUM58068.1 - 2.5 6.5 4.8 5.8 5.3 3.3 1.6 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.9 KUM58068.1 - 3.5 5.5 8.2 4.2 5.2 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein BCS1_N PF08740.6 KUM58069.1 - 1.1e-52 178.3 0.1 1.5e-52 177.9 0.1 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KUM58069.1 - 2.8e-18 66.3 0.0 5.6e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KUM58069.1 - 4.7e-05 24.2 0.0 0.00013 22.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KUM58069.1 - 0.00017 21.8 0.0 0.00048 20.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 KUM58069.1 - 0.00053 20.0 0.1 0.0028 17.6 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 KUM58069.1 - 0.00087 18.2 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 KUM58069.1 - 0.00089 18.7 0.0 0.0022 17.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KUM58069.1 - 0.0021 18.1 0.0 0.0085 16.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KUM58069.1 - 0.0032 17.4 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KUM58069.1 - 0.0065 16.3 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KUM58069.1 - 0.0067 16.1 0.0 0.024 14.3 0.0 2.0 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 KUM58069.1 - 0.0069 16.5 0.0 0.023 14.8 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_29 PF13555.1 KUM58069.1 - 0.013 14.9 0.0 0.039 13.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KUM58069.1 - 0.019 15.2 0.0 0.048 13.9 0.0 1.7 1 0 0 1 1 1 0 ABC transporter DUF2735 PF10931.3 KUM58069.1 - 0.03 14.5 0.0 0.081 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2735) AAA_24 PF13479.1 KUM58069.1 - 0.04 13.4 0.0 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KUM58069.1 - 0.055 13.2 0.5 0.29 10.9 0.0 2.5 3 0 0 3 3 3 0 Part of AAA domain DUF258 PF03193.11 KUM58069.1 - 0.061 12.5 0.0 0.23 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 KaiC PF06745.8 KUM58069.1 - 0.066 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 KaiC Miro PF08477.8 KUM58069.1 - 0.094 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_28 PF13521.1 KUM58069.1 - 0.1 12.5 0.0 0.34 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KUM58069.1 - 0.12 12.2 0.0 0.34 10.8 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_11 PF13086.1 KUM58069.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Lactamase_B_2 PF12706.2 KUM58070.1 - 1.3e-41 142.2 0.0 1.7e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KUM58070.1 - 4.7e-11 42.6 0.0 3.6e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KUM58070.1 - 0.0027 17.3 3.4 0.093 12.3 1.2 2.9 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily BTB PF00651.26 KUM58071.1 - 1.7e-06 27.9 0.0 1e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain COX7B PF05392.6 KUM58071.1 - 0.074 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase chain VIIB zf-PARP PF00645.13 KUM58072.1 - 1.4e-19 70.0 0.1 3.7e-19 68.7 0.1 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region TRIQK PF15168.1 KUM58072.1 - 4.9 7.1 15.2 0.59 10.1 0.6 4.4 2 1 2 4 4 4 0 Triple QxxK/R motif-containing protein family TCO89 PF10452.4 KUM58073.1 - 0.028 13.3 1.6 0.039 12.8 1.1 1.1 1 0 0 1 1 1 0 TORC1 subunit TCO89 Nucleoplasmin PF03066.10 KUM58073.1 - 1.2 8.5 6.6 2.3 7.7 4.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 KUM58073.1 - 6.3 7.1 12.7 13 6.0 8.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain ABM PF03992.11 KUM58075.1 - 4e-05 23.5 0.0 5.7e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF482 PF04339.7 KUM58075.1 - 0.021 13.7 0.1 0.024 13.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF482 SelP_N PF04592.9 KUM58075.1 - 0.055 12.8 0.2 0.06 12.7 0.2 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region IPPT PF01715.12 KUM58078.1 - 1.2e-51 175.1 0.6 2.2e-51 174.3 0.4 1.4 1 0 0 1 1 1 1 IPP transferase zf-met PF12874.2 KUM58078.1 - 1e-06 28.7 3.0 1.7e-06 27.9 2.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KUM58078.1 - 1.4e-05 25.1 5.8 2.4e-05 24.3 4.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KUM58078.1 - 0.0096 16.0 2.2 0.025 14.6 1.5 1.7 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) B12-binding PF02310.14 KUM58078.1 - 0.16 11.8 0.1 0.38 10.6 0.1 1.6 1 0 0 1 1 1 0 B12 binding domain zf-C2H2 PF00096.21 KUM58078.1 - 0.26 11.6 1.5 0.53 10.7 1.0 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Aminotran_5 PF00266.14 KUM58079.1 - 8.7e-28 97.1 0.0 1.9e-17 63.1 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V DUF4328 PF14219.1 KUM58079.1 - 0.015 14.6 0.0 0.073 12.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) NAD_binding_1 PF00175.16 KUM58080.1 - 5.2e-08 33.4 0.0 0.0006 20.3 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KUM58080.1 - 3.3e-06 27.1 0.0 1.9e-05 24.7 0.0 2.4 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KUM58080.1 - 0.0003 20.7 0.0 0.0014 18.5 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain AA_permease_2 PF13520.1 KUM58081.1 - 1.4e-61 208.3 40.7 3.3e-61 207.1 28.2 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM58081.1 - 2.5e-28 98.6 25.5 2.5e-28 98.6 17.6 2.3 2 1 0 2 2 2 1 Amino acid permease DUF4097 PF13349.1 KUM58081.1 - 0.19 11.2 0.3 0.55 9.7 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) NADHdeh_related PF10125.4 KUM58081.1 - 0.6 9.2 11.9 0.02 14.0 3.5 1.9 2 0 0 2 2 2 0 NADH dehydrogenase I, subunit N related protein Glyco_hydro_32N PF00251.15 KUM58082.1 - 2e-47 162.0 0.1 3.1e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 KUM58082.1 - 0.0001 22.6 0.0 0.0002 21.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 KUM58082.1 - 0.0018 17.7 1.4 0.18 11.7 0.0 3.3 2 0 0 2 2 2 1 BNR/Asp-box repeat Pkinase PF00069.20 KUM58083.1 - 1.8e-45 155.1 0.0 3.3e-45 154.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM58083.1 - 2.5e-26 92.3 0.0 4.2e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_12 PF13424.1 KUM58083.1 - 1.4e-10 40.9 1.4 0.02 14.8 0.0 4.0 3 1 0 3 3 3 3 Tetratricopeptide repeat Apc3 PF12895.2 KUM58083.1 - 3.4e-07 30.2 1.3 0.0056 16.7 1.3 2.7 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 KUM58083.1 - 3.5e-05 23.3 0.8 0.41 10.3 2.1 2.7 2 0 0 2 2 2 2 TPR repeat TPR_15 PF13429.1 KUM58083.1 - 0.00015 20.9 5.3 0.15 11.0 0.1 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat Kinase-like PF14531.1 KUM58083.1 - 0.00084 18.3 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like TPR_2 PF07719.12 KUM58083.1 - 0.0045 16.8 9.6 5 7.2 0.3 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 KUM58083.1 - 0.0085 16.7 1.2 5.7 7.7 0.0 3.8 3 1 1 4 4 3 1 Tetratricopeptide repeat MF_alpha_N PF05436.6 KUM58083.1 - 0.01 15.4 0.2 6.8 6.4 0.0 2.5 2 0 0 2 2 2 0 Mating factor alpha precursor N-terminus TPR_8 PF13181.1 KUM58083.1 - 0.011 15.5 4.1 0.67 9.8 0.5 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KUM58083.1 - 0.011 16.0 1.1 3.1 8.2 0.1 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 KUM58083.1 - 0.041 14.5 0.3 17 6.4 0.0 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KUM58083.1 - 0.042 13.6 1.3 7.6 6.6 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 KUM58083.1 - 0.47 10.1 9.0 17 5.2 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.20 KUM58084.1 - 1.8e-08 33.8 0.0 2.9e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM58084.1 - 8.2e-05 21.8 0.0 0.00025 20.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase UspB PF10625.4 KUM58084.1 - 0.12 12.1 0.1 0.36 10.6 0.0 1.8 2 0 0 2 2 2 0 Universal stress protein B (UspB) Sugar_tr PF00083.19 KUM58085.1 - 2.1e-76 257.3 13.9 2.6e-76 257.0 9.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM58085.1 - 6.5e-22 77.7 32.2 6e-20 71.2 10.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TspO_MBR PF03073.10 KUM58085.1 - 0.82 9.1 13.3 0.061 12.8 4.7 2.4 2 0 0 2 2 2 0 TspO/MBR family Fungal_trans PF04082.13 KUM58086.1 - 5.2e-13 48.4 1.0 6e-13 48.2 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Amidase PF01425.16 KUM58087.1 - 1e-100 337.7 0.0 1.2e-100 337.4 0.0 1.0 1 0 0 1 1 1 1 Amidase Imm29 PF15575.1 KUM58088.1 - 0.027 14.0 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 29 Rep_fac_C PF08542.6 KUM58089.1 - 3.3e-20 71.8 0.0 7e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KUM58089.1 - 1e-11 44.7 0.0 9.6e-10 38.3 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KUM58089.1 - 8e-11 42.2 0.0 1.4e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KUM58089.1 - 6.2e-07 29.3 0.0 2.3e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 KUM58089.1 - 3.4e-06 26.0 0.0 0.033 12.8 0.0 2.3 2 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 KUM58089.1 - 4.2e-06 25.9 0.0 9.9e-06 24.7 0.0 1.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KUM58089.1 - 2e-05 24.6 0.1 0.00054 19.9 0.0 2.4 1 1 2 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KUM58089.1 - 3.6e-05 23.8 0.1 0.0095 16.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KUM58089.1 - 8.4e-05 22.1 0.1 0.048 13.0 0.0 2.2 1 1 1 2 2 2 2 AAA-like domain AAA_3 PF07726.6 KUM58089.1 - 0.00012 21.6 0.0 0.00024 20.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 KUM58089.1 - 0.00016 21.3 0.0 0.00025 20.6 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DNA_pol3_delta PF06144.8 KUM58089.1 - 0.0018 17.8 0.0 0.0028 17.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_11 PF13086.1 KUM58089.1 - 0.005 16.4 0.0 0.0087 15.6 0.0 1.3 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KUM58089.1 - 0.0051 16.0 0.1 0.057 12.5 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KUM58089.1 - 0.0063 16.2 0.0 0.017 14.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain NTPase_1 PF03266.10 KUM58089.1 - 0.0065 16.1 0.3 0.064 12.9 0.1 2.3 1 1 0 2 2 2 1 NTPase DEAD PF00270.24 KUM58089.1 - 0.0097 15.4 0.1 0.56 9.6 0.0 2.5 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_25 PF13481.1 KUM58089.1 - 0.0098 15.3 0.1 0.054 12.9 0.1 2.4 2 1 1 3 3 3 1 AAA domain ArgK PF03308.11 KUM58089.1 - 0.01 14.6 0.1 0.027 13.2 0.0 1.6 1 1 1 2 2 2 0 ArgK protein KTI12 PF08433.5 KUM58089.1 - 0.029 13.6 0.0 0.052 12.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 FtsK_SpoIIIE PF01580.13 KUM58089.1 - 0.041 13.3 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.1 KUM58089.1 - 0.047 14.0 0.0 0.071 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.1 KUM58089.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KUM58089.1 - 0.11 11.3 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RAI1 PF08652.6 KUM58090.1 - 1.3e-29 101.7 0.0 3e-29 100.5 0.0 1.7 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease DUF410 PF04190.8 KUM58091.1 - 1.1e-46 159.5 0.0 1.4e-46 159.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) ABC_tran PF00005.22 KUM58092.1 - 6.4e-17 62.1 0.2 6.8e-16 58.8 0.1 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KUM58092.1 - 1.1e-10 41.9 0.4 4.2e-05 23.6 0.2 2.1 1 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KUM58092.1 - 5.2e-05 22.4 0.0 0.11 11.5 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KUM58092.1 - 0.00044 19.7 0.2 0.00081 18.8 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain PduV-EutP PF10662.4 KUM58092.1 - 0.00055 19.4 0.0 0.00076 18.9 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SMC_N PF02463.14 KUM58092.1 - 0.00078 18.7 0.1 0.31 10.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF3584 PF12128.3 KUM58092.1 - 0.0031 14.9 0.7 0.0041 14.5 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_25 PF13481.1 KUM58092.1 - 0.0063 15.9 0.1 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KUM58092.1 - 0.015 15.1 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KUM58092.1 - 0.016 16.0 0.2 0.033 14.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KUM58092.1 - 0.017 15.4 0.1 0.028 14.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KUM58092.1 - 0.02 14.3 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_28 PF13521.1 KUM58092.1 - 0.027 14.4 0.2 0.065 13.1 0.2 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KUM58092.1 - 0.053 12.7 0.0 0.078 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 KUM58092.1 - 0.077 13.1 0.7 0.49 10.5 0.5 2.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KUM58092.1 - 0.085 12.8 1.5 0.16 11.9 1.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.17 KUM58092.1 - 0.098 12.0 0.1 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Arf PF00025.16 KUM58092.1 - 0.12 11.5 0.1 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family KaiC PF06745.8 KUM58092.1 - 0.12 11.4 0.1 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.1 KUM58092.1 - 0.13 11.8 0.5 1.3 8.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KUM58092.1 - 0.14 12.3 0.1 0.73 10.0 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.4 KUM58092.1 - 0.15 10.6 0.1 0.22 10.0 0.1 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_13 PF13166.1 KUM58092.1 - 0.17 10.3 0.1 0.23 9.8 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KUM58092.1 - 0.2 11.3 0.6 1 9.1 0.1 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Pro_isomerase PF00160.16 KUM58093.1 - 4.3e-44 150.4 0.9 5.7e-44 150.0 0.6 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CcoS PF03597.10 KUM58093.1 - 3.5 7.1 6.0 2.1 7.8 0.4 2.3 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type DEAD PF00270.24 KUM58094.1 - 9.9e-46 155.3 0.0 2.4e-44 150.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM58094.1 - 3.1e-28 97.4 0.1 6.2e-28 96.4 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KUM58094.1 - 0.052 13.3 0.0 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.1 KUM58094.1 - 0.07 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 KUM58094.1 - 0.1 11.0 0.0 0.17 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) DUF4419 PF14388.1 KUM58095.1 - 1.8e-93 313.0 0.0 2.2e-93 312.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) RTA1 PF04479.8 KUM58096.1 - 1.2e-42 145.8 5.3 1.7e-42 145.4 3.7 1.1 1 0 0 1 1 1 1 RTA1 like protein HSA PF07529.8 KUM58097.1 - 6e-25 86.8 0.4 6e-25 86.8 0.3 3.8 4 0 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.1 KUM58097.1 - 5.1e-17 61.7 0.2 2.1e-16 59.7 0.1 2.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KUM58097.1 - 0.0068 16.4 1.9 0.02 14.9 0.1 2.7 3 0 0 3 3 3 1 Myb-like DNA-binding domain WD40 PF00400.27 KUM58098.1 - 2.5e-13 49.3 0.1 0.011 15.6 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat RAB3GAP2_N PF14655.1 KUM58098.1 - 0.064 12.2 0.0 0.19 10.7 0.0 1.8 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Peptidase_M16_C PF05193.16 KUM58099.1 - 7.2e-16 58.3 0.0 5.4e-09 35.9 0.0 2.8 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KUM58099.1 - 1.9e-05 24.4 0.0 6e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Sporozoite_P67 PF05642.6 KUM58099.1 - 8 4.1 7.9 11 3.7 5.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Zw10 PF06248.8 KUM58100.1 - 3.3e-14 51.9 0.7 9.6e-12 43.8 0.4 2.3 2 0 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 KUM58100.1 - 1e-08 34.7 0.7 1e-08 34.7 0.5 2.5 2 1 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal Syntaxin-6_N PF09177.6 KUM58100.1 - 0.041 14.2 5.2 0.041 14.2 0.0 3.6 3 1 0 3 3 3 0 Syntaxin 6, N-terminal Nop14 PF04147.7 KUM58100.1 - 3.6 5.3 28.8 0.19 9.5 14.5 2.2 2 0 0 2 2 2 0 Nop14-like family WD40 PF00400.27 KUM58101.1 - 3e-33 112.4 15.2 6.1e-07 29.0 0.2 6.8 6 1 0 6 6 6 5 WD domain, G-beta repeat NLE PF08154.7 KUM58101.1 - 1.1e-21 76.5 0.1 2.2e-21 75.6 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 KUM58101.1 - 0.0011 17.2 3.0 1.3 7.0 0.3 3.4 1 1 1 4 4 4 3 Nucleoporin Nup120/160 Ribosomal_S13 PF00416.17 KUM58102.1 - 4.4e-24 84.9 0.1 5e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 GTP_EFTU PF00009.22 KUM58103.1 - 5.9e-38 130.1 0.0 9.2e-38 129.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 KUM58103.1 - 2.4e-36 123.6 0.2 5.2e-36 122.5 0.2 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 KUM58103.1 - 4.1e-12 46.0 0.3 9.5e-12 44.8 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KUM58103.1 - 0.016 15.1 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Peptidase_M48 PF01435.13 KUM58104.1 - 2.4e-49 167.9 0.0 3.2e-49 167.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 DUF4538 PF15061.1 KUM58104.1 - 0.084 12.1 0.8 0.19 11.0 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) DUF2201_N PF13203.1 KUM58104.1 - 0.12 11.5 0.3 0.27 10.3 0.2 1.5 1 0 0 1 1 1 0 Putative metallopeptidase domain RNA_polI_A14 PF08203.6 KUM58105.1 - 3.4e-05 23.9 0.0 7.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Yeast RNA polymerase I subunit RPA14 PcfK PF14058.1 KUM58105.1 - 0.024 14.7 1.0 0.19 11.8 0.8 1.9 2 0 0 2 2 2 0 PcfK-like protein Ribosomal_L34 PF00468.12 KUM58106.1 - 1.4e-12 47.1 11.5 1.4e-12 47.1 8.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L34 Acyl-thio_N PF12590.3 KUM58106.1 - 0.059 13.8 0.3 0.11 12.9 0.2 1.5 1 0 0 1 1 1 0 Acyl-ATP thioesterase PPR_2 PF13041.1 KUM58107.1 - 3.4e-21 74.9 0.1 1.4e-15 56.9 0.0 3.2 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 KUM58107.1 - 7.8e-05 22.6 4.1 0.02 15.1 0.0 4.7 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR PF01535.15 KUM58107.1 - 0.00032 20.4 0.1 0.12 12.4 0.0 3.8 3 0 0 3 3 3 1 PPR repeat PPR_1 PF12854.2 KUM58107.1 - 0.067 12.6 0.7 25 4.4 0.0 3.5 4 0 0 4 4 4 0 PPR repeat DEAD PF00270.24 KUM58109.1 - 5.9e-23 81.1 0.0 1.2e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM58109.1 - 2e-11 43.6 0.0 5.3e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 KUM58109.1 - 4.3e-10 40.0 0.3 6.2e-09 36.3 0.2 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1998) CDT1 PF08839.6 KUM58109.1 - 0.00016 21.6 0.1 0.0003 20.7 0.0 1.5 1 1 0 1 1 1 1 DNA replication factor CDT1 like Neur PF00064.13 KUM58109.1 - 0.64 8.0 1.9 0.99 7.4 1.3 1.1 1 0 0 1 1 1 0 Neuraminidase Peptidase_S10 PF00450.17 KUM58110.1 - 8.5e-58 196.4 3.7 1.1e-57 196.1 2.6 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Yip1 PF04893.12 KUM58111.1 - 1e-11 44.6 17.1 1.8e-11 43.8 11.8 1.5 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 KUM58111.1 - 1.3 8.6 9.9 2.4 7.8 6.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) TraG_N PF07916.6 KUM58111.1 - 2.7 6.3 4.8 5 5.4 3.3 1.3 1 0 0 1 1 1 0 TraG-like protein, N-terminal region 7TM_transglut PF14402.1 KUM58111.1 - 5.8 5.7 9.2 7.5 5.3 6.4 1.1 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase Ran_BP1 PF00638.13 KUM58112.1 - 3.3e-17 62.6 0.1 4.9e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain Keratin_B2_2 PF13885.1 KUM58112.1 - 0.1 12.3 4.8 0.49 10.1 2.8 2.2 1 1 1 2 2 2 0 Keratin, high sulfur B2 protein Fungal_trans_2 PF11951.3 KUM58113.1 - 2.5e-12 46.1 1.1 4.6e-12 45.2 0.8 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM58113.1 - 1.7e-07 31.0 10.0 2.8e-07 30.3 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1387 PF07139.6 KUM58113.1 - 0.038 13.5 7.5 0.074 12.6 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Methyltransf_2 PF00891.13 KUM58114.1 - 1.5e-26 93.0 0.0 3e-26 92.0 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Bac_luciferase PF00296.15 KUM58116.1 - 8e-24 84.3 0.0 1e-23 83.9 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Con-6 PF10346.4 KUM58118.1 - 0.00071 18.9 0.0 0.0012 18.1 0.0 1.5 1 0 0 1 1 1 1 Conidiation protein 6 Hemerythrin PF01814.18 KUM58119.1 - 7.6e-15 55.2 3.1 7.6e-15 55.2 2.1 1.4 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain RTA1 PF04479.8 KUM58120.1 - 4e-38 131.1 7.6 4.8e-38 130.9 5.2 1.0 1 0 0 1 1 1 1 RTA1 like protein DUF4149 PF13664.1 KUM58120.1 - 0.71 9.9 5.6 1.2 9.1 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) AAA_17 PF13207.1 KUM58121.1 - 3.1e-07 31.2 0.0 2.4e-06 28.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KUM58121.1 - 7.2e-07 29.5 0.1 1.2e-05 25.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 KUM58121.1 - 3.2e-06 26.8 0.1 4.8e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 KUM58121.1 - 5.9e-05 22.9 0.0 0.0012 18.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KUM58121.1 - 7.2e-05 22.8 0.0 0.00014 21.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 KUM58121.1 - 0.00011 21.4 0.1 0.00065 18.8 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin SRP54 PF00448.17 KUM58121.1 - 0.00026 20.4 0.0 0.00039 19.9 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA PF00004.24 KUM58121.1 - 0.00061 19.9 0.0 0.00089 19.4 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KUM58121.1 - 0.001 18.7 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KUM58121.1 - 0.0017 18.5 0.0 0.003 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KUM58121.1 - 0.0018 18.0 0.0 0.0037 16.9 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 KUM58121.1 - 0.0023 16.9 0.0 0.0033 16.3 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein KTI12 PF08433.5 KUM58121.1 - 0.0024 17.1 0.0 0.0033 16.6 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Thymidylate_kin PF02223.12 KUM58121.1 - 0.003 16.9 0.1 0.05 12.9 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase FtsK_SpoIIIE PF01580.13 KUM58121.1 - 0.0055 16.2 0.0 0.0085 15.5 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family ArgK PF03308.11 KUM58121.1 - 0.0067 15.2 0.0 0.0089 14.8 0.0 1.2 1 0 0 1 1 1 1 ArgK protein NB-ARC PF00931.17 KUM58121.1 - 0.014 14.2 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.1 KUM58121.1 - 0.016 14.8 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KUM58121.1 - 0.017 14.6 0.0 0.017 14.6 0.0 1.3 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KUM58121.1 - 0.02 14.5 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 NTPase NACHT PF05729.7 KUM58121.1 - 0.025 14.2 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain APS_kinase PF01583.15 KUM58121.1 - 0.027 14.1 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF2075 PF09848.4 KUM58121.1 - 0.063 12.2 0.0 0.082 11.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 KUM58121.1 - 0.069 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 KUM58121.1 - 0.083 12.4 0.0 0.29 10.6 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 KUM58121.1 - 0.14 11.5 0.0 0.46 9.8 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain cobW PF02492.14 KUM58121.1 - 0.16 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.13 KUM58121.1 - 0.17 11.3 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF1900 PF08954.6 KUM58122.1 - 2.1e-50 169.8 0.0 4.7e-49 165.3 0.0 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 KUM58122.1 - 2.5e-33 113.5 0.0 4.4e-33 112.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 KUM58122.1 - 5.4e-23 79.9 1.7 2.3e-06 27.2 0.0 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 KUM58122.1 - 0.00014 20.1 0.2 0.16 10.0 0.1 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DivIC PF04977.10 KUM58122.1 - 0.059 12.8 1.5 0.12 11.8 1.0 1.4 1 0 0 1 1 1 0 Septum formation initiator SlyX PF04102.7 KUM58122.1 - 0.17 12.2 3.1 0.23 11.8 1.1 1.9 2 0 0 2 2 2 0 SlyX Lipase_3 PF01764.20 KUM58123.1 - 2e-18 66.3 0.0 3e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) MFS_1 PF07690.11 KUM58125.1 - 1.4e-14 53.6 16.9 1.4e-14 53.6 11.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF202 PF02656.10 KUM58125.1 - 0.017 15.3 1.0 0.24 11.6 0.0 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF202) RAI16-like PF10257.4 KUM58126.1 - 4.9e-86 288.8 0.1 7.3e-86 288.2 0.0 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein CBFD_NFYB_HMF PF00808.18 KUM58127.1 - 5.2e-16 58.4 2.0 8.2e-16 57.8 1.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KUM58127.1 - 2.9e-07 30.4 0.6 4.3e-07 29.9 0.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 zf-C3HC4_3 PF13920.1 KUM58128.1 - 0.0013 18.3 11.9 0.0021 17.6 8.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KUM58128.1 - 0.16 12.0 12.4 0.25 11.3 8.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KUM58128.1 - 1.5 8.7 6.6 2.5 7.9 4.6 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 KUM58128.1 - 2.7 7.7 12.9 4.2 7.1 9.0 1.3 1 0 0 1 1 1 0 zinc-RING finger domain FAD_binding_4 PF01565.18 KUM58129.1 - 8.3e-27 93.3 1.9 1.4e-26 92.5 1.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KUM58129.1 - 3.8e-14 52.3 0.0 1e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Abhydrolase_6 PF12697.2 KUM58131.1 - 8.6e-30 104.3 0.1 1.4e-29 103.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM58131.1 - 2e-18 66.8 0.0 3.6e-14 52.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KUM58131.1 - 1.7e-09 37.6 0.0 1e-08 35.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KUM58131.1 - 0.00069 18.1 0.0 0.0011 17.4 0.0 1.3 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.5 KUM58131.1 - 0.0073 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Thioesterase PF00975.15 KUM58131.1 - 0.04 14.1 0.1 0.06 13.5 0.1 1.5 1 1 0 1 1 1 0 Thioesterase domain DUF915 PF06028.6 KUM58131.1 - 0.091 11.8 0.0 0.27 10.3 0.0 1.4 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Kinesin PF00225.18 KUM58132.1 - 1.5e-105 352.6 0.8 1.5e-105 352.6 0.6 1.5 2 0 0 2 2 2 1 Kinesin motor domain Arch_ATPase PF01637.13 KUM58132.1 - 0.0011 18.7 4.0 0.88 9.2 0.0 2.8 2 1 1 3 3 3 2 Archaeal ATPase Laminin_I PF06008.9 KUM58132.1 - 0.0028 17.0 18.6 0.21 10.8 7.9 2.8 2 1 1 3 3 3 2 Laminin Domain I Tropomyosin_1 PF12718.2 KUM58132.1 - 0.0045 16.8 15.3 0.0045 16.8 10.6 2.2 2 1 0 2 2 2 1 Tropomyosin like Bac_DnaA PF00308.13 KUM58132.1 - 0.0098 15.5 1.4 0.019 14.6 0.0 2.2 3 0 0 3 3 3 1 Bacterial dnaA protein WEMBL PF05701.6 KUM58132.1 - 0.17 10.3 21.0 0.027 12.9 11.4 1.9 2 1 0 2 2 2 0 Weak chloroplast movement under blue light ArsR PF09824.4 KUM58132.1 - 0.18 11.1 3.3 0.55 9.5 0.0 2.9 4 0 0 4 4 4 0 ArsR transcriptional regulator Reo_sigmaC PF04582.7 KUM58132.1 - 0.23 10.6 6.7 0.7 9.0 0.3 2.8 2 1 0 2 2 2 0 Reovirus sigma C capsid protein AAA_22 PF13401.1 KUM58132.1 - 0.53 10.4 0.0 0.53 10.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_13 PF13166.1 KUM58132.1 - 0.95 7.8 15.0 0.12 10.7 5.8 2.3 2 1 0 2 2 2 0 AAA domain CENP-F_leu_zip PF10473.4 KUM58132.1 - 1.2 9.0 21.8 5.4 6.8 11.5 3.3 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 KUM58132.1 - 1.2 8.8 14.2 1 9.0 7.8 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.7 KUM58132.1 - 2.6 7.8 11.7 1.8 8.3 1.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4200 PF13863.1 KUM58132.1 - 5.4 6.9 33.4 0.45 10.4 6.6 3.3 2 2 1 3 3 3 0 Domain of unknown function (DUF4200) IF-2B PF01008.12 KUM58133.1 - 1.3e-17 63.7 0.0 3.5e-17 62.3 0.0 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.23 KUM58133.1 - 9.7e-12 44.6 0.2 1.7e-11 43.8 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain p450 PF00067.17 KUM58134.1 - 2.5e-45 154.8 0.0 5.8e-45 153.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 NmrA PF05368.8 KUM58135.1 - 6e-30 104.2 0.0 9.6e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KUM58135.1 - 1.5e-08 34.8 0.0 2.7e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KUM58135.1 - 1.6e-07 30.3 0.0 3.8e-07 29.1 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KUM58135.1 - 1.9e-06 27.5 0.0 2.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KUM58135.1 - 0.0018 18.2 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM58135.1 - 0.02 14.5 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 KR domain Zn_clus PF00172.13 KUM58136.1 - 2.5e-09 36.8 11.1 6.2e-09 35.6 7.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.17 KUM58137.1 - 4.5e-186 618.7 0.8 5.1e-186 618.5 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ADH_N PF08240.7 KUM58138.1 - 8.1e-30 102.7 1.2 1.7e-29 101.7 0.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM58138.1 - 5e-24 84.2 0.3 5e-24 84.2 0.2 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KUM58138.1 - 0.0043 16.2 0.2 0.0071 15.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KUM58138.1 - 0.016 14.7 0.3 0.025 14.1 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.1 KUM58138.1 - 0.022 15.6 0.0 0.04 14.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF1537 PF07005.6 KUM58138.1 - 0.12 12.0 1.0 0.19 11.3 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF1537 Grp1_Fun34_YaaH PF01184.14 KUM58139.1 - 1.2e-26 93.3 18.7 1.5e-26 92.9 13.0 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Ank_2 PF12796.2 KUM58140.1 - 1.2e-55 185.8 0.0 8.3e-15 54.9 0.0 6.8 4 2 0 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 KUM58140.1 - 4e-43 143.1 13.9 0.00021 20.9 0.0 13.0 15 0 0 15 15 15 11 Ankyrin repeat Ank_3 PF13606.1 KUM58140.1 - 2.6e-34 113.8 10.4 0.032 14.4 0.0 13.7 16 0 0 16 16 16 9 Ankyrin repeat Ank_4 PF13637.1 KUM58140.1 - 1.3e-32 111.5 2.4 4.4e-06 27.0 0.0 10.1 7 2 4 11 11 11 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM58140.1 - 1.6e-29 101.2 9.3 0.03 14.5 0.0 11.4 7 4 4 12 12 12 7 Ankyrin repeats (many copies) DUF1110 PF06533.7 KUM58140.1 - 0.026 14.3 0.1 5.1 6.8 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1110) GST_N_3 PF13417.1 KUM58142.1 - 1e-10 41.6 0.0 2e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KUM58142.1 - 1.5e-09 37.7 0.0 2.4e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KUM58142.1 - 0.0002 21.1 0.5 0.00068 19.4 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain His_Phos_1 PF00300.17 KUM58144.1 - 0.096 12.7 0.0 0.14 12.2 0.0 1.3 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) SURF6 PF04935.7 KUM58145.1 - 1.2e-48 165.2 36.6 1.2e-48 165.2 25.4 3.9 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 KUM58145.1 - 5.1e-23 80.9 2.1 5.1e-23 80.9 1.4 8.5 7 2 0 7 7 7 1 60S ribosome biogenesis protein Rrp14 CAF-1_p150 PF11600.3 KUM58145.1 - 0.0039 16.5 22.1 0.0039 16.5 15.3 4.2 2 1 2 4 4 4 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ribosomal_S2 PF00318.15 KUM58146.1 - 9.5e-50 168.7 0.0 1.3e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S2 BBE PF08031.7 KUM58146.1 - 0.046 13.6 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like Rick_17kDa_Anti PF05433.10 KUM58147.1 - 9.2e-05 22.0 14.4 0.00018 21.0 10.0 1.6 1 0 0 1 1 1 1 Glycine zipper 2TM domain DUF533 PF04391.7 KUM58147.1 - 0.0072 15.7 2.1 0.0072 15.7 1.5 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF533) Gly-zipper_Omp PF13488.1 KUM58147.1 - 0.24 11.0 16.2 1.1 8.9 10.9 2.4 1 1 1 2 2 2 0 Glycine zipper TraT PF05818.7 KUM58147.1 - 0.32 10.3 2.1 0.53 9.6 1.5 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Transgly_assoc PF04226.8 KUM58147.1 - 0.6 10.2 11.2 1 9.4 7.8 1.4 1 0 0 1 1 1 0 Transglycosylase associated protein GPP34 PF05719.6 KUM58148.1 - 3.8e-64 216.5 0.1 5e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) ADH_zinc_N_2 PF13602.1 KUM58149.1 - 0.0026 18.6 0.1 0.0067 17.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fer4 PF00037.22 KUM58150.1 - 5.3e-14 51.1 16.4 3.1e-08 32.8 2.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 KUM58150.1 - 2.7e-12 46.8 10.8 4.3e-12 46.2 7.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 KUM58150.1 - 1.8e-10 40.4 23.7 2.4e-08 33.6 9.1 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 KUM58150.1 - 2.7e-10 40.3 9.3 5.1e-10 39.4 6.5 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 KUM58150.1 - 9.7e-10 38.1 5.2 5.7e-05 22.8 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 KUM58150.1 - 1e-09 38.9 8.3 6.1e-05 23.6 0.5 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_17 PF13534.1 KUM58150.1 - 5.9e-09 36.1 2.3 0.00067 19.9 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 KUM58150.1 - 9e-09 35.2 20.1 1.6e-05 24.8 8.3 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 KUM58150.1 - 1.1e-07 31.3 14.3 0.00057 19.6 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 KUM58150.1 - 4.1e-07 29.8 12.5 0.00056 20.0 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 KUM58150.1 - 5.9e-07 29.0 17.4 0.0012 18.6 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 KUM58150.1 - 4.2e-05 23.8 9.9 0.014 15.8 0.5 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 KUM58150.1 - 0.003 18.0 12.7 0.32 11.5 1.3 2.8 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_13 PF13370.1 KUM58150.1 - 0.0083 16.4 15.7 0.29 11.5 3.2 2.7 2 1 0 2 2 2 2 4Fe-4S single cluster domain c-SKI_SMAD_bind PF08782.5 KUM58150.1 - 0.016 15.3 4.3 0.35 11.0 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_3 PF12798.2 KUM58150.1 - 0.018 15.5 17.5 0.039 14.5 2.8 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_11 PF13247.1 KUM58150.1 - 0.11 12.4 4.4 0.18 11.6 3.1 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain PP-binding PF00550.20 KUM58151.1 - 1.4e-10 41.2 0.1 1.9e-10 40.8 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 KUM58151.1 - 3.3e-05 23.8 0.1 4.1e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Acyl-carrier Ribosomal_L50 PF10501.4 KUM58151.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.5 1 1 0 1 1 1 0 Ribosomal subunit 39S DUF2183 PF09949.4 KUM58152.1 - 2.5e-31 107.5 0.0 4.8e-31 106.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) His_Phos_1 PF00300.17 KUM58153.1 - 1.2e-27 96.9 0.1 1.4e-27 96.7 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Acetyltransf_3 PF13302.1 KUM58154.1 - 1.1e-37 129.3 0.0 1.4e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KUM58154.1 - 0.00066 19.6 0.1 0.0049 16.8 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KUM58154.1 - 0.0015 18.4 0.0 0.1 12.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KUM58154.1 - 0.003 17.4 0.0 2.6 7.9 0.0 2.8 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain But2 PF09792.4 KUM58155.1 - 1.8e-54 183.4 1.1 3.5e-54 182.4 0.8 1.5 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain UNC-50 PF05216.8 KUM58156.1 - 0.0052 16.0 2.0 0.012 14.8 1.4 1.5 1 0 0 1 1 1 1 UNC-50 family MARVEL PF01284.18 KUM58156.1 - 0.064 13.0 15.7 0.098 12.4 10.9 1.2 1 0 0 1 1 1 0 Membrane-associating domain 7TMR-DISM_7TM PF07695.6 KUM58156.1 - 3 7.4 18.4 0.17 11.5 8.3 1.9 1 1 1 2 2 2 0 7TM diverse intracellular signalling PLDc_N PF13396.1 KUM58156.1 - 3.3 7.4 13.4 0.072 12.7 1.4 3.0 2 1 0 2 2 2 0 Phospholipase_D-nuclease N-terminal HemY_N PF07219.8 KUM58156.1 - 4.5 6.8 8.1 12 5.5 0.0 2.7 2 1 1 3 3 3 0 HemY protein N-terminus zf-DHHC PF01529.15 KUM58156.1 - 7.6 5.8 11.4 3e+02 0.7 7.9 2.1 1 1 0 1 1 1 0 DHHC palmitoyltransferase PAP2 PF01569.16 KUM58157.1 - 1.8e-26 92.3 2.0 2e-26 92.2 0.3 1.8 2 0 0 2 2 2 1 PAP2 superfamily 7tm_1 PF00001.16 KUM58157.1 - 0.0091 15.1 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Cyto_ox_2 PF02322.10 KUM58157.1 - 0.023 13.8 0.2 5.1 6.1 0.0 2.2 2 0 0 2 2 2 0 Cytochrome oxidase subunit II Fungal_trans PF04082.13 KUM58158.1 - 6.8e-15 54.6 0.0 1e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAA_hydrolase PF01557.13 KUM58159.1 - 1.6e-58 197.6 0.0 2.1e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Cupin_2 PF07883.6 KUM58160.1 - 3.1e-18 65.0 0.1 3e-08 33.0 0.0 2.2 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KUM58160.1 - 0.0066 15.8 0.0 1.5 8.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 KUM58160.1 - 0.007 16.0 0.6 2.6 7.7 0.0 2.7 2 1 1 3 3 3 2 AraC-like ligand binding domain CENP-C_C PF11699.3 KUM58160.1 - 0.013 15.4 0.0 0.057 13.4 0.0 1.8 2 0 0 2 2 2 0 Mif2/CENP-C like DUF3830 PF12903.2 KUM58161.1 - 3.6e-29 101.0 0.0 4.1e-29 100.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3830) Amidohydro_4 PF13147.1 KUM58162.1 - 3.7e-23 82.9 0.0 8.3e-23 81.7 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KUM58162.1 - 3.2e-16 59.9 0.0 3.7e-07 30.1 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KUM58162.1 - 9.7e-14 50.9 0.4 2.1e-13 49.8 0.3 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KUM58162.1 - 2.8e-07 30.1 0.8 0.0024 17.1 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family Urease_alpha PF00449.15 KUM58162.1 - 0.00069 19.7 0.2 0.0017 18.5 0.2 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Fungal_trans PF04082.13 KUM58165.1 - 2.3e-23 82.4 0.4 5.3e-23 81.2 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain TauD PF02668.11 KUM58166.1 - 4.6e-37 128.0 0.3 5.7e-37 127.7 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 KUM58166.1 - 0.0024 18.3 0.3 1.1 9.7 0.2 2.4 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily DPRP PF04244.8 KUM58166.1 - 0.029 13.9 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein S-AdoMet_synt_C PF02773.11 KUM58167.1 - 3.9e-77 256.6 1.2 2.1e-76 254.2 0.2 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 KUM58167.1 - 5.9e-46 155.3 0.0 1e-45 154.5 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 KUM58167.1 - 1.5e-42 143.9 0.7 2.3e-42 143.2 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Lactamase_B_3 PF13483.1 KUM58167.1 - 0.054 13.1 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain DUF2312 PF10073.4 KUM58167.1 - 0.098 12.0 0.3 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) AA_permease PF00324.16 KUM58168.1 - 3.6e-94 315.7 44.9 1.9e-53 181.4 18.7 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 KUM58168.1 - 1.9e-22 79.4 44.7 3.5e-14 52.1 18.5 2.0 1 1 1 2 2 2 2 Amino acid permease DUF1772 PF08592.6 KUM58169.1 - 0.007 16.1 1.0 0.12 12.1 0.4 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1772) DUF420 PF04238.7 KUM58169.1 - 0.014 15.3 3.8 0.014 15.3 2.6 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF420) SLD3 PF08639.5 KUM58170.1 - 3.2e-148 494.4 7.3 3.2e-148 494.4 5.1 1.7 2 0 0 2 2 2 1 DNA replication regulator SLD3 DHDPS PF00701.17 KUM58171.1 - 5.9e-30 103.8 0.0 5.3e-29 100.7 0.0 2.0 1 1 1 2 2 2 2 Dihydrodipicolinate synthetase family ATP_bind_1 PF03029.12 KUM58172.1 - 3.9e-75 252.4 0.2 4.5e-75 252.2 0.2 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 KUM58172.1 - 1.3e-05 25.9 0.0 5.2e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 KUM58172.1 - 0.00033 19.6 0.3 0.00071 18.5 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_14 PF13173.1 KUM58172.1 - 0.00041 20.2 0.0 0.00085 19.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KUM58172.1 - 0.0011 18.4 0.0 0.0022 17.4 0.0 2.0 1 1 0 1 1 1 1 AAA-like domain AAA_19 PF13245.1 KUM58172.1 - 0.0012 18.5 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 KUM58172.1 - 0.0012 18.7 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KUM58172.1 - 0.0027 17.7 0.0 0.0083 16.1 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KUM58172.1 - 0.0032 17.5 0.0 0.008 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.1 KUM58172.1 - 0.0034 17.3 0.0 0.015 15.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KUM58172.1 - 0.0051 16.9 0.0 0.013 15.6 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 KUM58172.1 - 0.0076 15.8 0.1 0.03 13.9 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 KUM58172.1 - 0.0085 16.2 0.0 0.022 14.9 0.0 1.7 1 0 0 1 1 1 1 RNA helicase GTP_EFTU PF00009.22 KUM58172.1 - 0.011 15.1 0.1 4.3 6.7 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Zeta_toxin PF06414.7 KUM58172.1 - 0.015 14.3 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin cobW PF02492.14 KUM58172.1 - 0.015 14.7 0.1 0.37 10.2 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 KUM58172.1 - 0.017 14.6 0.0 0.049 13.1 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.22 KUM58172.1 - 0.02 15.1 0.0 0.06 13.6 0.0 1.7 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.7 KUM58172.1 - 0.02 14.5 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 KUM58172.1 - 0.023 14.2 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KAP_NTPase PF07693.9 KUM58172.1 - 0.025 13.5 0.0 0.067 12.1 0.0 1.9 1 1 0 1 1 1 0 KAP family P-loop domain Sigma54_activat PF00158.21 KUM58172.1 - 0.027 13.9 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain MobB PF03205.9 KUM58172.1 - 0.031 13.9 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 KUM58172.1 - 0.032 13.6 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Gtr1_RagA PF04670.7 KUM58172.1 - 0.034 13.2 0.0 0.077 12.1 0.0 2.0 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region ArsA_ATPase PF02374.10 KUM58172.1 - 0.037 13.0 0.0 0.088 11.8 0.0 1.5 2 0 0 2 2 2 0 Anion-transporting ATPase AAA_30 PF13604.1 KUM58172.1 - 0.041 13.4 0.1 0.092 12.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 KUM58172.1 - 0.054 12.5 0.0 0.11 11.5 0.0 1.5 2 0 0 2 2 1 0 Septin RuvB_N PF05496.7 KUM58172.1 - 0.054 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus MMR_HSR1 PF01926.18 KUM58172.1 - 0.074 13.0 0.0 0.26 11.2 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.9 KUM58172.1 - 0.086 12.5 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_35 PF14516.1 KUM58172.1 - 0.092 11.3 0.0 1.2 7.6 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain Arch_ATPase PF01637.13 KUM58172.1 - 0.11 12.2 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase KaiC PF06745.8 KUM58172.1 - 0.11 11.6 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 KaiC Apq12 PF12716.2 KUM58173.1 - 4.8e-18 64.5 14.2 8.1e-18 63.8 9.9 1.4 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis PI3_PI4_kinase PF00454.22 KUM58175.1 - 4.1e-36 124.6 0.0 6e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase MutL_C PF08676.6 KUM58176.1 - 6.8e-24 84.1 1.0 9.8e-24 83.6 0.0 1.8 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 KUM58176.1 - 2e-18 65.9 0.1 2.3e-17 62.5 0.0 2.8 3 0 0 3 3 3 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KUM58176.1 - 1.9e-13 50.2 0.1 6.3e-13 48.5 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KUM58176.1 - 2.7e-12 46.3 0.0 8.7e-12 44.7 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase bZIP_1 PF00170.16 KUM58177.1 - 4.5e-05 23.3 1.4 0.00012 21.9 1.0 1.7 1 0 0 1 1 1 1 bZIP transcription factor Glutaredoxin2_C PF04399.8 KUM58177.1 - 0.053 13.1 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DUF2034 PF10356.4 KUM58178.1 - 1.2e-42 145.2 0.0 2.4e-26 92.0 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 KUM58178.1 - 3.3e-08 33.3 0.0 7e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease Med21 PF11221.3 KUM58179.1 - 8.9e-59 197.6 1.0 1.4e-58 196.9 0.7 1.3 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.8 KUM58179.1 - 0.0041 16.8 3.2 0.1 12.3 2.6 2.4 1 1 1 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 DUF4515 PF14988.1 KUM58179.1 - 0.0099 15.5 0.6 0.017 14.8 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4515) APG6 PF04111.7 KUM58179.1 - 0.029 13.4 0.7 0.042 12.9 0.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Cortex-I_coil PF09304.5 KUM58179.1 - 0.031 14.2 2.1 0.048 13.6 1.4 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil DUF4455 PF14643.1 KUM58179.1 - 0.042 12.4 0.3 0.058 12.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Rabaptin PF03528.10 KUM58179.1 - 0.07 13.0 0.8 0.11 12.4 0.5 1.2 1 0 0 1 1 1 0 Rabaptin Spore_III_AB PF09548.5 KUM58179.1 - 0.12 12.1 0.5 0.19 11.5 0.1 1.4 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) FlgM PF04316.8 KUM58179.1 - 2.3 8.2 5.3 0.31 11.0 0.9 1.7 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM adh_short PF00106.20 KUM58180.1 - 3e-22 79.2 0.5 4e-22 78.8 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM58180.1 - 4.6e-12 46.2 0.1 5.8e-12 45.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM58180.1 - 1.7e-06 27.8 0.2 2.7e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KUM58180.1 - 5.4e-06 25.7 0.0 1.6e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KUM58180.1 - 0.00023 21.2 0.2 0.00095 19.2 0.2 1.9 1 1 0 1 1 1 1 NADH(P)-binding ADH_zinc_N PF00107.21 KUM58180.1 - 0.018 14.5 0.1 0.036 13.6 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase SNF2_N PF00176.18 KUM58181.1 - 2.6e-64 216.8 0.1 3.8e-64 216.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KUM58181.1 - 3e-06 27.0 0.0 1e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 KUM58181.1 - 0.02 14.6 5.7 0.037 13.7 4.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 KUM58181.1 - 0.03 14.1 7.4 0.071 12.9 5.2 1.7 1 0 0 1 1 1 0 Ring finger domain Aminotran_5 PF00266.14 KUM58182.1 - 2.2e-20 72.7 0.0 3.2e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KUM58182.1 - 1.1e-05 24.5 0.0 1.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Pro_CA PF00484.14 KUM58183.1 - 5.5e-19 68.6 0.0 7.6e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase LEH PF07858.7 KUM58183.1 - 0.099 12.6 0.2 0.23 11.4 0.0 1.6 2 0 0 2 2 2 0 Limonene-1,2-epoxide hydrolase catalytic domain Fis1_TPR_C PF14853.1 KUM58184.1 - 1.4e-24 85.7 0.4 2.2e-24 85.0 0.3 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 KUM58184.1 - 5.5e-16 57.5 0.0 8.4e-16 56.9 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 KUM58184.1 - 0.011 15.5 1.4 0.011 15.5 1.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KUM58184.1 - 0.028 15.1 0.2 0.055 14.1 0.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF357 PF04010.8 KUM58184.1 - 0.052 13.2 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF357) DdrB PF12747.2 KUM58184.1 - 0.068 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 DdrB-like protein Spc24 PF08286.6 KUM58185.1 - 1.2e-39 134.7 1.3 1.8e-38 130.8 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Streptin-Immun PF11083.3 KUM58185.1 - 0.0078 16.1 0.5 0.091 12.7 0.0 2.2 2 0 0 2 2 2 1 Lantibiotic streptin immunity protein Prefoldin_2 PF01920.15 KUM58185.1 - 0.01 15.5 2.5 1.9 8.2 1.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit APG6 PF04111.7 KUM58185.1 - 0.096 11.7 5.5 0.12 11.3 3.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4613 PF15390.1 KUM58185.1 - 0.11 10.6 2.1 0.13 10.3 1.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF3166 PF11365.3 KUM58185.1 - 0.24 11.8 3.5 0.19 12.2 1.0 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3166) DMPK_coil PF08826.5 KUM58185.1 - 0.66 9.9 9.7 1.1 9.2 0.7 2.2 2 0 0 2 2 2 0 DMPK coiled coil domain like Viral_P18 PF04521.8 KUM58185.1 - 2.4 7.6 5.5 0.78 9.2 0.4 2.1 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein FlaC_arch PF05377.6 KUM58185.1 - 3.7 7.5 5.2 28 4.7 0.0 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF724 PF05266.9 KUM58185.1 - 5.7 6.5 8.0 21 4.6 1.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Lge1 PF11488.3 KUM58185.1 - 7.6 6.8 8.5 0.8 9.9 0.6 2.2 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 GCN5L1 PF06320.8 KUM58186.1 - 7.9e-15 54.7 2.2 1.9e-14 53.5 1.4 1.6 2 0 0 2 2 2 1 GCN5-like protein 1 (GCN5L1) Syntaxin-6_N PF09177.6 KUM58186.1 - 0.047 14.1 0.7 0.11 12.9 0.2 1.8 1 1 0 2 2 2 0 Syntaxin 6, N-terminal APH PF01636.18 KUM58186.1 - 1.4 8.5 5.6 7.9 6.1 3.9 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Nodulin-like PF06813.8 KUM58187.1 - 7.6e-24 84.3 1.2 1.6e-23 83.2 0.8 1.5 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.11 KUM58187.1 - 6.4e-15 54.7 40.3 1.8e-13 49.9 10.8 2.8 1 1 1 3 3 3 2 Major Facilitator Superfamily GATA PF00320.22 KUM58188.1 - 8.8e-16 56.9 2.6 1.6e-15 56.1 1.8 1.5 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 KUM58188.1 - 0.019 14.2 0.4 0.037 13.3 0.3 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding DivIVA PF05103.8 KUM58188.1 - 0.049 13.6 0.2 0.095 12.7 0.2 1.4 1 0 0 1 1 1 0 DivIVA protein Pox_A_type_inc PF04508.7 KUM58188.1 - 0.14 12.0 0.4 0.14 12.0 0.3 3.3 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat CENP-F_leu_zip PF10473.4 KUM58188.1 - 0.19 11.5 5.1 7.6 6.3 1.3 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 KUM58188.1 - 0.45 10.0 2.5 0.69 9.4 1.7 1.3 1 0 0 1 1 1 0 IncA protein bZIP_2 PF07716.10 KUM58188.1 - 2 8.2 8.6 13 5.7 0.1 2.4 2 0 0 2 2 2 0 Basic region leucine zipper WD40_alt PF14077.1 KUM58188.1 - 3.7 7.2 5.9 10 5.8 0.1 3.1 2 1 1 3 3 3 0 Alternative WD40 repeat motif Serinc PF03348.10 KUM58189.1 - 2.3e-174 580.1 13.1 2.7e-174 579.9 9.0 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) PGA2 PF07543.7 KUM58189.1 - 0.54 10.0 2.9 17 5.2 0.0 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 AMP-binding PF00501.23 KUM58190.1 - 9.4e-151 501.9 0.0 4.3e-80 269.1 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KUM58190.1 - 3e-65 220.0 0.0 1.1e-34 119.6 0.1 3.4 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.20 KUM58190.1 - 8.8e-23 80.3 0.6 4e-11 43.0 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KUM58190.1 - 1.3e-15 58.0 0.0 6.3e-07 30.2 0.0 2.9 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain GH3 PF03321.8 KUM58190.1 - 3 6.2 6.3 3 6.2 0.0 3.2 5 0 0 5 5 5 0 GH3 auxin-responsive promoter GP41 PF00517.12 KUM58191.1 - 0.057 12.9 5.7 0.058 12.9 4.0 1.0 1 0 0 1 1 1 0 Retroviral envelope protein DUF4389 PF14333.1 KUM58191.1 - 0.79 9.4 5.5 0.95 9.2 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) Pex24p PF06398.6 KUM58191.1 - 2.3 6.9 6.8 2.1 7.0 4.7 1.0 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin HemY_N PF07219.8 KUM58191.1 - 3.4 7.2 6.9 3.9 7.0 4.8 1.2 1 0 0 1 1 1 0 HemY protein N-terminus Sigma_reg_N PF13800.1 KUM58191.1 - 6.4 6.8 6.7 7.6 6.6 4.6 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Asn_synthase PF00733.16 KUM58193.1 - 9.8e-52 175.9 0.0 1.5e-51 175.4 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KUM58193.1 - 3.7e-36 123.6 0.0 7.4e-36 122.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KUM58193.1 - 3.8e-31 107.7 0.0 8.1e-31 106.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KUM58193.1 - 0.00021 20.5 0.0 0.00042 19.5 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein tRNA_Me_trans PF03054.11 KUM58193.1 - 0.031 12.8 0.0 0.046 12.2 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase GATase_2 PF00310.16 KUM58193.1 - 0.078 11.6 0.1 1 8.0 0.0 2.4 1 1 2 3 3 3 0 Glutamine amidotransferases class-II Ras PF00071.17 KUM58194.1 - 5.1e-40 136.5 0.0 6.4e-38 129.6 0.0 2.0 2 0 0 2 2 2 1 Ras family Miro PF08477.8 KUM58194.1 - 5.7e-18 65.5 0.0 8.9e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KUM58194.1 - 7.7e-12 44.7 0.0 1.5e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KUM58194.1 - 0.00042 19.5 0.0 0.0005 19.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KUM58194.1 - 0.00043 19.5 0.0 0.00058 19.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KUM58194.1 - 0.0023 17.8 0.0 0.0035 17.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KUM58194.1 - 0.011 15.7 0.1 0.053 13.4 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 KUM58194.1 - 0.015 15.4 0.0 0.031 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KUM58194.1 - 0.065 12.9 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 KUM58194.1 - 0.086 12.8 0.2 0.22 11.4 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KUM58194.1 - 0.099 12.5 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KUM58194.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KUM58194.1 - 0.18 11.4 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase GATase PF00117.23 KUM58195.1 - 1.5e-11 44.1 0.0 1.8e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KUM58195.1 - 0.0087 15.5 0.0 0.02 14.3 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 FAD_binding_4 PF01565.18 KUM58196.1 - 8.9e-20 70.5 2.4 1.6e-19 69.7 1.2 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KUM58196.1 - 8.8e-07 28.7 0.1 1.9e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.20 KUM58197.1 - 2.2e-12 47.2 0.1 4.2e-12 46.2 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KUM58197.1 - 2e-05 24.3 0.0 4.3e-05 23.2 0.1 1.5 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KUM58197.1 - 9.4e-05 22.4 0.1 0.00013 22.0 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KUM58197.1 - 0.01 15.3 0.0 0.016 14.6 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sugar_tr PF00083.19 KUM58198.1 - 4e-100 335.5 26.4 4.6e-100 335.3 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM58198.1 - 8.4e-24 83.9 36.0 2.3e-13 49.5 7.6 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.7 KUM58198.1 - 3.2 7.7 8.8 1.2 9.1 0.0 3.2 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 PNP_UDP_1 PF01048.15 KUM58200.1 - 4.6e-17 61.7 0.0 1.2e-16 60.4 0.0 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily DOMON PF03351.12 KUM58201.1 - 0.0036 17.2 0.1 0.0074 16.2 0.0 1.6 1 0 0 1 1 1 1 DOMON domain AMP-binding PF00501.23 KUM58202.1 - 2.6e-231 767.2 0.0 2.7e-82 276.4 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 KUM58202.1 - 9.2e-165 546.8 0.3 2.9e-42 144.5 0.0 6.4 6 1 0 6 6 6 5 Condensation domain PP-binding PF00550.20 KUM58202.1 - 1.5e-39 134.0 0.0 5.1e-13 49.0 0.0 3.7 3 0 0 3 3 3 3 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 KUM58202.1 - 0.0017 18.6 0.0 0.0089 16.3 0.0 2.4 1 0 0 1 1 1 1 HxxPF-repeated domain DUF2600 PF10776.4 KUM58202.1 - 0.26 10.0 0.0 0.48 9.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2600) DUF43 PF01861.11 KUM58202.1 - 0.71 8.8 0.0 1.4 7.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF43 zf-C2H2_2 PF12756.2 KUM58203.1 - 0.027 14.5 4.3 0.024 14.7 1.6 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Gly_transf_sug PF04488.10 KUM58204.1 - 7e-09 36.0 0.0 1.4e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 KUM58204.1 - 0.01 15.0 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein ABC_tran PF00005.22 KUM58205.1 - 1.1e-34 119.6 0.0 2e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KUM58205.1 - 1.7e-26 93.2 6.6 2.3e-26 92.8 4.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.1 KUM58205.1 - 2.5e-09 37.3 0.1 5.5e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 KUM58205.1 - 3e-06 27.4 0.0 0.0032 17.4 0.0 2.3 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 KUM58205.1 - 1e-05 24.9 0.4 0.0048 16.1 0.0 2.7 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KUM58205.1 - 0.00024 20.3 0.0 0.00039 19.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KUM58205.1 - 0.0006 19.9 0.1 0.012 15.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KUM58205.1 - 0.00072 19.0 0.0 0.08 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KUM58205.1 - 0.00093 20.0 0.0 0.0018 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_ATPase PF09818.4 KUM58205.1 - 0.0014 17.3 0.0 0.011 14.3 0.0 2.0 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_5 PF07728.9 KUM58205.1 - 0.002 17.8 0.0 0.039 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.24 KUM58205.1 - 0.0051 17.0 0.0 0.98 9.6 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 KUM58205.1 - 0.009 15.5 0.1 0.021 14.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MobB PF03205.9 KUM58205.1 - 0.029 14.0 0.0 0.36 10.5 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KUM58205.1 - 0.032 14.1 0.2 0.078 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KUM58205.1 - 0.059 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 KUM58205.1 - 0.12 11.7 0.0 0.57 9.6 0.0 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_membrane PF00664.18 KUM58206.1 - 1.1e-34 120.1 11.9 1.1e-34 120.1 8.3 2.2 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.22 KUM58206.1 - 1.6e-30 106.1 0.0 3.3e-30 105.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KUM58206.1 - 5.1e-07 29.1 1.5 7e-05 22.1 0.4 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KUM58206.1 - 2.5e-05 23.7 0.1 6.1e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KUM58206.1 - 6.2e-05 23.1 0.1 0.0012 18.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KUM58206.1 - 0.00041 19.5 0.0 0.00098 18.3 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 KUM58206.1 - 0.0013 18.7 0.0 0.19 11.6 0.0 2.3 1 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 KUM58206.1 - 0.0078 16.5 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KUM58206.1 - 0.0091 15.7 0.0 0.029 14.1 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_10 PF12846.2 KUM58206.1 - 0.013 14.9 0.1 0.095 12.1 0.0 2.4 2 1 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 KUM58206.1 - 0.022 15.5 0.0 0.049 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.4 KUM58206.1 - 0.044 12.3 0.1 0.18 10.3 0.0 1.9 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DUF3987 PF13148.1 KUM58206.1 - 0.056 12.0 0.0 0.096 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_30 PF13604.1 KUM58206.1 - 0.061 12.8 0.2 0.91 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KUM58206.1 - 0.075 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KUM58206.1 - 0.083 12.8 0.0 0.32 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.15 KUM58206.1 - 0.09 11.4 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit MobB PF03205.9 KUM58206.1 - 0.095 12.4 0.1 0.28 10.8 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KUM58206.1 - 0.12 12.3 0.0 0.99 9.3 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase Phage_lysozyme PF00959.14 KUM58207.1 - 7.4e-12 45.5 0.1 1.1e-11 44.9 0.1 1.2 1 0 0 1 1 1 1 Phage lysozyme PNP_UDP_1 PF01048.15 KUM58208.1 - 2.8e-05 23.1 0.3 0.00025 20.0 0.2 1.9 2 0 0 2 2 2 1 Phosphorylase superfamily Lentiviral_Tat PF02998.9 KUM58209.1 - 0.078 12.8 0.1 1 9.2 0.0 2.4 2 0 0 2 2 2 0 Lentiviral Tat protein Phasin PF05597.6 KUM58210.1 - 0.002 17.8 1.4 0.0032 17.2 1.0 1.2 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) TroA PF01297.12 KUM58210.1 - 0.0037 16.5 0.4 0.0055 15.9 0.3 1.2 1 0 0 1 1 1 1 Periplasmic solute binding protein family DUF883 PF05957.8 KUM58210.1 - 0.0074 16.6 6.5 0.017 15.4 2.6 2.2 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 KUM58210.1 - 0.041 13.3 3.5 0.082 12.4 2.4 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF2884 PF11101.3 KUM58210.1 - 0.072 12.4 0.3 0.088 12.1 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) DUF743 PF05332.6 KUM58210.1 - 0.086 12.8 1.0 0.12 12.3 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF743) PG_binding_4 PF12229.3 KUM58210.1 - 0.095 12.9 1.1 0.17 12.1 0.5 1.6 1 1 0 1 1 1 0 Putative peptidoglycan binding domain Prominin PF05478.6 KUM58210.1 - 0.17 9.3 0.0 0.19 9.2 0.0 1.0 1 0 0 1 1 1 0 Prominin V-ATPase_G PF03179.10 KUM58210.1 - 0.44 10.8 4.8 0.75 10.1 3.3 1.3 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 KUM58210.1 - 0.72 9.6 8.8 1 9.1 6.1 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Borrelia_P83 PF05262.6 KUM58210.1 - 2.5 6.2 8.7 3.3 5.8 6.0 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein zf-H2C2_2 PF13465.1 KUM58211.1 - 6e-06 26.2 4.0 6e-06 26.2 2.8 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 KUM58211.1 - 2.6e-05 24.2 14.7 0.011 15.9 1.3 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KUM58211.1 - 5.2e-05 23.2 15.8 0.0043 17.2 1.5 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger TylF PF05711.6 KUM58211.1 - 0.11 11.5 0.0 0.53 9.3 0.0 1.9 2 0 0 2 2 2 0 Macrocin-O-methyltransferase (TylF) COG5 PF10392.4 KUM58212.1 - 1.7e-40 138.0 0.6 5.5e-40 136.3 0.4 1.9 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Aldolase_II PF00596.16 KUM58215.1 - 1.4e-45 155.1 0.1 1.8e-45 154.7 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain tRNA-synt_2 PF00152.15 KUM58216.1 - 2.4e-70 236.9 0.0 3.6e-70 236.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KUM58216.1 - 1.3e-07 31.4 0.0 2.2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Trypan_glycop PF00913.14 KUM58216.1 - 0.61 8.9 7.4 0.93 8.3 5.1 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) SERTA PF06031.8 KUM58217.1 - 0.012 14.8 0.1 0.03 13.6 0.1 1.6 1 0 0 1 1 1 0 SERTA motif P16-Arc PF04699.9 KUM58217.1 - 0.053 13.5 0.7 0.064 13.2 0.5 1.1 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF1762 PF08574.5 KUM58221.1 - 1.6e-19 70.1 12.9 1.6e-19 70.1 8.9 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1762) PepSY PF03413.14 KUM58221.1 - 3.1 8.4 6.4 5.7 7.6 0.0 3.2 3 1 0 3 3 3 0 Peptidase propeptide and YPEB domain Nop14 PF04147.7 KUM58221.1 - 7.6 4.3 11.2 11 3.8 7.8 1.2 1 0 0 1 1 1 0 Nop14-like family RRM_6 PF14259.1 KUM58222.1 - 1.4e-38 130.7 0.0 2e-10 40.5 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KUM58222.1 - 4.1e-37 125.6 0.0 1.7e-11 43.5 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM58222.1 - 9.4e-17 60.6 0.0 0.0015 18.3 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 KUM58222.1 - 1.2e-14 53.5 4.1 6.8e-14 51.1 2.9 2.4 1 0 0 1 1 1 1 Putative RRM domain RRM_3 PF08777.6 KUM58222.1 - 2.5e-05 24.0 0.0 0.082 12.7 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif RNA_bind PF08675.6 KUM58222.1 - 0.024 14.5 0.0 1.8 8.6 0.0 3.2 3 0 0 3 3 3 0 RNA binding domain MT-A70 PF05063.9 KUM58223.1 - 9e-22 77.4 0.1 1.6e-15 57.1 0.0 2.9 2 1 0 2 2 2 2 MT-A70 PUF PF00806.14 KUM58224.1 - 1.2e-27 93.8 0.0 3.2e-05 23.1 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 KUM58224.1 - 4.5e-10 39.0 0.0 1e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM58224.1 - 5.4e-07 29.3 0.0 1.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM58224.1 - 3.7e-05 23.5 0.0 9.3e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) YL1 PF05764.8 KUM58226.1 - 7.5e-57 192.6 19.8 7.5e-57 192.6 13.8 3.0 2 1 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.6 KUM58226.1 - 2.4e-11 42.9 0.5 2.4e-11 42.9 0.4 1.9 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Fungal_trans PF04082.13 KUM58227.1 - 1.5e-12 46.9 1.0 1.9e-12 46.6 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 KUM58229.1 - 3.4e-10 39.2 6.0 7.2e-10 38.1 4.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sulfatase PF00884.18 KUM58230.1 - 1.1e-57 195.6 0.0 1.4e-57 195.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KUM58230.1 - 5.5e-06 25.9 1.6 0.0011 18.4 1.1 2.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase MR_MLE PF01188.16 KUM58231.1 - 4.9e-14 52.6 0.0 1e-13 51.5 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_C PF13378.1 KUM58231.1 - 1.3e-12 47.6 0.0 3.1e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 KUM58231.1 - 0.0002 21.3 0.0 0.00041 20.3 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain NACHT PF05729.7 KUM58232.1 - 5.7e-12 45.6 0.7 2.1e-11 43.7 0.0 2.4 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.1 KUM58232.1 - 2.7e-05 24.3 1.5 0.0011 19.1 0.0 3.6 4 1 0 4 4 4 1 AAA domain AAA_16 PF13191.1 KUM58232.1 - 0.00018 21.5 0.5 0.00018 21.5 0.3 3.6 2 2 1 3 3 3 1 AAA ATPase domain DUF4615 PF15393.1 KUM58232.1 - 0.0022 18.2 0.5 0.0045 17.2 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4615) ABC_tran PF00005.22 KUM58232.1 - 0.042 14.1 1.2 0.15 12.3 0.0 2.3 2 1 0 2 2 2 0 ABC transporter AAA_10 PF12846.2 KUM58232.1 - 0.052 12.9 0.9 0.34 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 KUM58232.1 - 0.55 11.0 2.5 2 9.2 0.1 3.1 2 2 0 2 2 2 0 AAA domain DUF87 PF01935.12 KUM58232.1 - 0.59 9.9 4.6 1.1 9.0 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function DUF87 Epimerase PF01370.16 KUM58235.1 - 2.2e-17 63.2 0.0 3.5e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KUM58235.1 - 5.6e-16 59.0 0.0 1.4e-15 57.7 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KUM58235.1 - 4.5e-15 55.1 0.0 7.9e-15 54.3 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KUM58235.1 - 2.9e-09 36.2 0.8 5.1e-08 32.1 0.6 2.0 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KUM58235.1 - 1.8e-07 31.2 0.0 2.9e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 KUM58235.1 - 7e-07 28.7 0.0 1.2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 KUM58235.1 - 1.6e-05 24.6 0.1 3.5e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KUM58235.1 - 0.00031 19.7 0.0 0.00048 19.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sugar_tr PF00083.19 KUM58236.1 - 4.3e-107 358.4 14.9 4.9e-107 358.2 10.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM58236.1 - 1.2e-26 93.2 35.7 5e-24 84.6 9.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KUM58236.1 - 0.0033 15.7 5.2 0.0039 15.4 0.2 2.3 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 KUM58236.1 - 0.029 14.1 0.0 0.029 14.1 0.0 2.7 3 0 0 3 3 3 0 MFS_1 like family MFS_3 PF05977.8 KUM58236.1 - 0.073 11.1 3.5 1 7.3 0.2 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector DUF3176 PF11374.3 KUM58237.1 - 6.2e-40 135.5 0.9 1.3e-39 134.4 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Tim17 PF02466.14 KUM58238.1 - 1.3e-33 115.7 6.0 1.6e-33 115.4 4.2 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HATPase_c_4 PF13749.1 KUM58238.1 - 0.033 13.9 0.0 0.05 13.3 0.0 1.4 1 1 0 1 1 1 0 ATP-dependent DNA helicase recG C-terminal CorA PF01544.13 KUM58239.1 - 1.9e-15 56.7 3.0 4.4e-15 55.4 2.1 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein adh_short_C2 PF13561.1 KUM58240.1 - 2.3e-23 83.2 0.3 3.6e-23 82.5 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KUM58240.1 - 3.5e-08 33.5 0.7 4.7e-08 33.1 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM58240.1 - 6.5e-05 22.6 0.2 0.00018 21.2 0.1 1.6 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 KUM58240.1 - 0.00057 19.6 0.1 0.0016 18.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 KUM58240.1 - 0.0097 14.9 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Helicase_RecD PF05127.9 KUM58240.1 - 0.018 14.6 0.2 0.34 10.5 0.2 2.1 1 1 0 1 1 1 0 Helicase DELLA PF12041.3 KUM58240.1 - 0.033 13.8 0.1 0.07 12.7 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal PrsW-protease PF13367.1 KUM58240.1 - 0.04 13.0 0.0 0.066 12.4 0.0 1.2 1 0 0 1 1 1 0 Protease prsW family DUF3109 PF11307.3 KUM58240.1 - 0.18 11.2 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3109) Abhydrolase_5 PF12695.2 KUM58243.1 - 1.9e-11 43.8 0.2 2.4e-10 40.3 0.1 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KUM58243.1 - 5.1e-10 39.6 1.5 5.1e-10 39.6 1.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KUM58243.1 - 0.0002 20.6 0.9 0.00031 20.0 0.1 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 KUM58243.1 - 0.0026 17.0 0.0 0.0055 16.0 0.0 1.6 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.15 KUM58243.1 - 0.022 14.2 0.0 0.042 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.15 KUM58243.1 - 0.19 11.2 2.3 0.4 10.2 1.6 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold ADH_zinc_N PF00107.21 KUM58244.1 - 4.4e-07 29.5 0.0 6.9e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM58244.1 - 0.012 15.3 0.1 0.035 13.8 0.1 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain FAD_binding_4 PF01565.18 KUM58246.1 - 1.3e-18 66.8 1.9 3e-18 65.6 1.3 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KUM58246.1 - 4.2e-09 36.1 0.1 8.6e-09 35.1 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like NAD_binding_8 PF13450.1 KUM58248.1 - 8.5e-11 41.7 0.0 2e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KUM58248.1 - 5.5e-08 32.3 0.0 9e-07 28.3 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 KUM58248.1 - 2.7e-06 27.5 0.1 1.4e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KUM58248.1 - 0.003 17.4 0.0 0.01 15.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KUM58248.1 - 0.0069 15.5 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 KUM58248.1 - 0.0074 16.0 0.1 0.037 13.8 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 KUM58248.1 - 0.0084 15.0 0.1 0.016 14.1 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KUM58248.1 - 0.023 13.1 0.0 0.036 12.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 KUM58248.1 - 0.033 13.2 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 KUM58248.1 - 0.038 13.0 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase TUDOR PF00567.19 KUM58248.1 - 0.047 13.5 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 Tudor domain Lycopene_cycl PF05834.7 KUM58248.1 - 0.051 12.4 0.1 0.087 11.7 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.13 KUM58248.1 - 0.052 13.5 0.1 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_2 PF00890.19 KUM58248.1 - 0.12 11.1 0.1 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain p450 PF00067.17 KUM58249.1 - 4.8e-65 219.8 0.0 1.1e-64 218.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KUM58251.1 - 7.5e-27 93.9 0.1 9.8e-26 90.2 0.1 2.0 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 KUM58252.1 - 5.7e-10 39.1 0.0 8.3e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM58252.1 - 3.6e-09 36.9 0.0 6.8e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM58252.1 - 3.5e-07 29.9 0.0 5.2e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM58252.1 - 6.5e-07 29.9 0.0 1.7e-06 28.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM58252.1 - 2.5e-06 27.8 0.0 7.7e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM58252.1 - 6.3e-06 26.4 0.0 1.5e-05 25.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KUM58252.1 - 1.2e-05 24.5 0.0 2.1e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KUM58252.1 - 0.0016 18.4 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 KUM58252.1 - 0.031 13.5 0.0 0.072 12.3 0.0 1.5 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain NAS PF03059.11 KUM58252.1 - 0.046 12.8 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 Nicotianamine synthase protein DUF4331 PF14224.1 KUM58252.1 - 0.11 11.6 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4331) AMP-binding PF00501.23 KUM58253.1 - 1.6e-78 263.9 0.0 2.9e-78 263.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 KUM58253.1 - 5.4e-72 242.3 0.0 1.4e-71 240.9 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.15 KUM58253.1 - 7e-49 166.2 0.1 1.5e-48 165.2 0.1 1.5 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.1 KUM58253.1 - 7.7e-48 163.1 0.4 1.5e-47 162.2 0.3 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 KUM58253.1 - 2.1e-47 161.1 0.1 4.2e-45 153.6 0.0 2.8 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 KUM58253.1 - 1.7e-45 155.7 0.2 3.1e-45 154.9 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.7 KUM58253.1 - 3.9e-40 137.3 0.0 1.1e-39 135.8 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KUM58253.1 - 2.9e-39 134.6 3.8 1.8e-35 122.3 0.0 3.7 4 0 0 4 4 3 2 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KUM58253.1 - 5.4e-30 103.6 0.0 1.5e-29 102.2 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Epimerase PF01370.16 KUM58253.1 - 1.8e-19 70.1 0.0 3.7e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_12 PF08242.7 KUM58253.1 - 6.8e-19 68.1 0.0 2.2e-18 66.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM58253.1 - 4.6e-17 62.1 0.0 1.2e-16 60.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KUM58253.1 - 1.7e-14 53.8 0.5 1.8e-06 28.0 0.0 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 KUM58253.1 - 1.2e-13 51.3 0.0 3.2e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM58253.1 - 1.6e-13 50.5 0.0 4.3e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 KUM58253.1 - 3e-10 40.2 0.0 9.2e-10 38.7 0.0 1.9 1 0 0 1 1 1 1 HxxPF-repeated domain Methyltransf_18 PF12847.2 KUM58253.1 - 2.8e-09 37.5 0.0 2.6e-08 34.4 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KUM58253.1 - 6.1e-09 35.3 0.0 1.1e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family 3Beta_HSD PF01073.14 KUM58253.1 - 7.2e-09 34.7 0.0 1.3e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KUM58253.1 - 1.2e-07 31.9 0.0 3.6e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 NADH(P)-binding Thiolase_N PF00108.18 KUM58253.1 - 3.3e-05 23.0 0.0 6.7e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain MTS PF05175.9 KUM58253.1 - 0.001 18.4 0.0 0.0032 16.8 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 KUM58253.1 - 0.011 15.1 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase RrnaAD PF00398.15 KUM58253.1 - 0.018 14.1 0.0 0.035 13.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase F420_oxidored PF03807.12 KUM58253.1 - 0.073 13.5 0.0 1.2 9.6 0.0 2.8 3 0 0 3 3 2 0 NADP oxidoreductase coenzyme F420-dependent Methyltransf_8 PF05148.10 KUM58253.1 - 1.8 8.1 0.0 3.6 7.1 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase MFS_1 PF07690.11 KUM58254.1 - 0.55 8.8 5.4 0.82 8.3 3.6 1.4 1 1 0 1 1 1 0 Major Facilitator Superfamily DUF521 PF04412.8 KUM58255.1 - 4.2e-140 466.8 0.0 5.2e-140 466.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF521) DUF126 PF01989.11 KUM58255.1 - 1.5e-31 107.9 0.0 3.4e-31 106.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function DUF126 MoaC PF01967.16 KUM58256.1 - 2.2e-47 160.1 0.2 3.4e-47 159.5 0.2 1.3 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 KUM58256.1 - 1.7e-35 121.4 0.0 5.8e-35 119.7 0.0 1.9 1 1 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 KUM58256.1 - 3.2e-16 59.9 0.0 6e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily p450 PF00067.17 KUM58257.1 - 1.4e-63 215.0 0.0 1.6e-63 214.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC_tran PF00005.22 KUM58259.1 - 3.1e-25 89.0 3.3 1.9e-13 50.8 0.2 3.0 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 KUM58259.1 - 1e-08 34.9 5.6 1.7e-08 34.1 3.9 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KUM58259.1 - 3.7e-08 33.6 0.0 0.0063 16.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_13 PF13166.1 KUM58259.1 - 0.0043 15.5 0.9 0.17 10.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KUM58259.1 - 0.0087 15.3 2.9 0.96 8.6 0.0 2.6 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF3584 PF12128.3 KUM58259.1 - 0.012 12.9 0.8 0.012 12.9 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_23 PF13476.1 KUM58259.1 - 0.017 15.4 2.2 0.11 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KUM58259.1 - 0.018 15.0 0.1 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF258 PF03193.11 KUM58259.1 - 0.051 12.7 0.7 0.11 11.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 KUM58259.1 - 0.065 12.7 0.3 0.29 10.6 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Miro PF08477.8 KUM58259.1 - 0.066 13.7 0.1 0.16 12.4 0.1 1.7 1 0 0 1 1 1 0 Miro-like protein cobW PF02492.14 KUM58259.1 - 0.11 11.9 0.9 0.19 11.1 0.2 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 KUM58259.1 - 0.12 13.2 0.8 0.42 11.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain TORC_M PF12885.2 KUM58259.1 - 0.13 12.0 1.1 0.44 10.3 0.8 1.8 1 1 0 1 1 1 0 Transducer of regulated CREB activity middle domain MobB PF03205.9 KUM58259.1 - 0.25 11.0 1.4 0.28 10.8 0.1 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 KUM58259.1 - 0.51 9.1 2.8 2.1 7.1 0.8 2.3 2 1 0 2 2 2 0 Type II/IV secretion system protein Gtr1_RagA PF04670.7 KUM58262.1 - 8.9e-71 237.7 0.2 4.1e-70 235.5 0.0 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Arf PF00025.16 KUM58262.1 - 0.0005 19.3 0.0 0.00088 18.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KUM58262.1 - 0.0014 19.1 0.0 0.0034 17.8 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KUM58262.1 - 0.0098 15.1 0.0 0.024 13.8 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 KUM58262.1 - 0.051 13.0 0.1 0.083 12.4 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.1 KUM58262.1 - 0.053 13.4 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Lactamase_B_2 PF12706.2 KUM58263.1 - 6.7e-30 104.0 0.1 1.3e-29 103.1 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 KUM58263.1 - 2.5e-23 81.3 0.1 5.2e-23 80.2 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 KUM58263.1 - 3.1e-05 23.7 0.0 0.00012 21.8 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Fusion_gly PF00523.13 KUM58263.1 - 5 5.0 4.9 12 3.8 0.0 2.1 2 0 0 2 2 2 0 Fusion glycoprotein F0 His_Phos_2 PF00328.17 KUM58264.1 - 1.4e-22 80.4 0.0 6.9e-22 78.2 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) bZIP_1 PF00170.16 KUM58265.1 - 4.9e-07 29.6 11.9 9.5e-07 28.6 8.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KUM58265.1 - 0.0038 17.0 11.7 0.0038 17.0 8.1 2.3 3 0 0 3 3 3 1 Basic region leucine zipper cobW PF02492.14 KUM58266.1 - 1.4e-47 161.4 5.4 2.3e-36 124.8 0.4 2.3 1 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 KUM58266.1 - 2.2e-20 72.1 0.1 4.1e-16 58.4 0.0 2.8 3 0 0 3 3 3 2 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.9 KUM58266.1 - 0.00047 19.8 0.1 0.0013 18.4 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 KUM58266.1 - 0.0084 15.8 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase AAA_33 PF13671.1 KUM58266.1 - 0.011 15.6 0.1 0.069 13.0 0.1 2.4 2 1 0 2 2 2 0 AAA domain Nucleoplasmin PF03066.10 KUM58266.1 - 0.012 15.1 0.8 0.012 15.1 0.6 2.5 2 0 0 2 2 2 0 Nucleoplasmin UPF0079 PF02367.12 KUM58266.1 - 0.014 15.0 0.0 0.035 13.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 KUM58266.1 - 0.025 14.7 0.2 0.071 13.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KUM58266.1 - 0.029 13.8 0.0 0.062 12.8 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 KUM58266.1 - 0.032 13.1 0.4 0.057 12.3 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_16 PF13191.1 KUM58266.1 - 0.048 13.6 0.5 0.16 11.9 0.4 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 KUM58266.1 - 0.048 13.9 6.2 0.053 13.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 KUM58266.1 - 0.05 13.1 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 KUM58266.1 - 0.064 13.1 0.1 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KUM58266.1 - 0.23 10.1 1.5 1.5 7.5 0.1 2.5 2 1 0 2 2 2 0 ArgK protein CDC45 PF02724.9 KUM58266.1 - 1.3 6.9 14.1 0.024 12.7 0.8 2.2 2 0 0 2 2 2 0 CDC45-like protein AAA_11 PF13086.1 KUM58266.1 - 1.9 8.0 5.4 5.4 6.5 0.1 2.9 2 1 1 3 3 3 0 AAA domain BSP_II PF05432.6 KUM58266.1 - 1.9 7.6 14.2 0.91 8.7 2.2 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) adh_short PF00106.20 KUM58267.1 - 1.9e-18 66.9 0.3 4.3e-18 65.7 0.2 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM58267.1 - 6.8e-07 29.3 0.0 9.2e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM58267.1 - 2.2e-05 24.2 0.1 3.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KUM58267.1 - 0.017 15.0 0.1 0.046 13.7 0.1 1.5 1 1 0 1 1 1 0 NADH(P)-binding DUF1776 PF08643.5 KUM58267.1 - 0.044 12.9 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ABC_tran PF00005.22 KUM58268.1 - 5.7e-08 33.1 0.1 9.3e-08 32.4 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_28 PF13521.1 KUM58268.1 - 0.00031 20.7 0.0 0.00062 19.7 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_29 PF13555.1 KUM58268.1 - 0.00044 19.7 0.0 0.00084 18.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 KUM58268.1 - 0.0023 17.9 0.0 0.0031 17.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 KUM58268.1 - 0.0066 16.3 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 KUM58268.1 - 0.0079 17.0 0.0 0.014 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 KUM58268.1 - 0.017 15.6 0.0 0.13 12.7 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein AAA_23 PF13476.1 KUM58268.1 - 0.025 14.9 0.1 0.062 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.12 KUM58268.1 - 0.028 14.2 0.3 0.064 13.0 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function DUF87 AAA_18 PF13238.1 KUM58268.1 - 0.037 14.3 0.0 0.088 13.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KUM58268.1 - 0.038 13.7 0.0 0.089 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KUM58268.1 - 0.038 13.8 0.1 0.079 12.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KUM58268.1 - 0.038 14.1 0.0 0.059 13.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KUM58268.1 - 0.044 13.4 0.0 0.076 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain G-alpha PF00503.15 KUM58268.1 - 0.047 12.3 0.1 0.055 12.1 0.1 1.2 1 0 0 1 1 1 0 G-protein alpha subunit DUF258 PF03193.11 KUM58268.1 - 0.054 12.6 0.4 0.42 9.7 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 KUM58268.1 - 0.056 13.6 0.0 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.1 KUM58268.1 - 0.057 12.8 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KUM58268.1 - 0.059 13.3 0.1 0.095 12.6 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 KUM58268.1 - 0.063 12.7 0.1 0.092 12.2 0.1 1.4 1 1 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.1 KUM58268.1 - 0.064 13.3 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KUM58268.1 - 0.083 12.5 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF815 PF05673.8 KUM58268.1 - 0.094 11.6 0.2 0.12 11.2 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 KUM58268.1 - 0.13 12.2 0.0 0.36 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain Ribul_P_3_epim PF00834.14 KUM58269.1 - 4.1e-61 205.5 0.0 6.7e-60 201.6 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.9 KUM58269.1 - 0.043 12.9 0.3 0.059 12.4 0.2 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG QRPTase_C PF01729.14 KUM58269.1 - 0.052 13.0 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain OMPdecase PF00215.19 KUM58269.1 - 0.098 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Amidohydro_2 PF04909.9 KUM58269.1 - 0.14 11.7 0.3 9.7 5.6 0.0 2.5 1 1 0 2 2 2 0 Amidohydrolase MFS_1 PF07690.11 KUM58270.1 - 1e-43 149.4 43.7 1.4e-43 148.9 30.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM58270.1 - 1.8e-13 49.8 30.0 1.8e-12 46.5 13.3 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 KUM58270.1 - 2e-06 26.2 14.0 2.7e-06 25.8 9.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GST_N_3 PF13417.1 KUM58271.1 - 3.1e-13 49.7 0.0 6.3e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KUM58271.1 - 1.3e-11 44.3 0.0 3.3e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KUM58271.1 - 0.00025 21.1 0.0 0.00042 20.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KUM58271.1 - 0.00025 20.8 0.0 0.00066 19.5 0.0 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KUM58271.1 - 0.001 19.4 0.0 0.0017 18.7 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KUM58271.1 - 0.032 14.2 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.11 KUM58273.1 - 1.8e-08 33.4 29.2 6.2e-07 28.4 20.2 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM58273.1 - 2e-05 22.9 6.5 2.5e-05 22.6 4.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 KUM58273.1 - 0.061 13.1 13.1 0.62 9.8 0.1 3.5 3 0 0 3 3 3 0 MFS_1 like family Alpha-L-AF_C PF06964.7 KUM58274.1 - 1.3e-36 126.0 0.0 2.4e-36 125.1 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus CBM_4_9 PF02018.12 KUM58274.1 - 0.043 13.8 0.3 0.11 12.4 0.2 1.8 1 0 0 1 1 1 0 Carbohydrate binding domain TPR_12 PF13424.1 KUM58276.1 - 4.9e-36 122.5 1.6 1.4e-12 47.3 0.1 4.7 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 KUM58276.1 - 5e-28 96.1 0.0 1.3e-06 28.1 0.0 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat Patatin PF01734.17 KUM58276.1 - 4e-14 53.0 0.0 9.8e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_11 PF13414.1 KUM58276.1 - 2.8e-11 42.9 0.1 7e-07 28.8 0.0 3.3 2 2 2 4 4 4 3 TPR repeat NB-ARC PF00931.17 KUM58276.1 - 1.1e-09 37.5 0.0 4.8e-09 35.4 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain TPR_2 PF07719.12 KUM58276.1 - 3.1e-09 36.0 2.7 0.038 13.9 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat NACHT PF05729.7 KUM58276.1 - 2.7e-06 27.1 0.0 5.5e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_7 PF13176.1 KUM58276.1 - 3.2e-06 26.5 6.3 0.93 9.4 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KUM58276.1 - 1.1e-05 25.6 0.4 0.74 10.1 0.0 4.1 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KUM58276.1 - 0.0001 22.6 0.3 16 6.4 0.0 5.1 3 1 2 5 5 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 KUM58276.1 - 0.00014 22.4 0.0 0.76 10.5 0.0 4.1 2 2 3 5 5 5 2 Tetratricopeptide repeat AAA_22 PF13401.1 KUM58276.1 - 0.00031 20.8 0.0 0.0011 19.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain TPR_1 PF00515.23 KUM58276.1 - 0.00033 20.1 3.1 1.4 8.6 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 KUM58276.1 - 0.0004 19.9 2.1 28 4.8 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 KUM58276.1 - 0.014 15.8 2.3 7.9 7.1 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat IstB_IS21 PF01695.12 KUM58276.1 - 0.015 14.7 0.0 0.037 13.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Arylsulfotran_2 PF14269.1 KUM58277.1 - 2.8e-65 220.4 0.3 3.6e-62 210.2 0.2 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KUM58277.1 - 1e-10 40.7 0.1 2.2e-09 36.3 0.0 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) NUMOD4 PF07463.6 KUM58277.1 - 0.11 12.4 0.0 11 6.0 0.0 3.1 3 0 0 3 3 3 0 NUMOD4 motif PQQ PF01011.16 KUM58277.1 - 0.19 11.3 1.9 13 5.5 0.0 3.8 4 0 0 4 4 4 0 PQQ enzyme repeat ABC2_membrane PF01061.19 KUM58278.1 - 8.3e-96 319.1 58.4 6.5e-49 165.9 13.4 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KUM58278.1 - 1.1e-37 129.4 0.0 3.4e-18 66.2 0.0 3.0 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 KUM58278.1 - 1.2e-31 108.4 5.9 4.5e-30 103.3 0.0 3.3 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 KUM58278.1 - 1.8e-25 88.8 0.1 3.5e-25 87.8 0.1 1.5 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 KUM58278.1 - 2.9e-10 39.7 36.4 9.5e-09 34.7 8.1 2.8 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 KUM58278.1 - 2.2e-05 23.9 0.0 0.013 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KUM58278.1 - 0.00043 19.5 0.1 0.058 12.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 KUM58278.1 - 0.00067 19.9 0.0 0.15 12.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KUM58278.1 - 0.0014 18.1 0.9 0.073 12.5 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 KUM58278.1 - 0.0044 16.5 0.8 0.72 9.4 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 KUM58278.1 - 0.0057 16.5 0.1 0.36 10.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KUM58278.1 - 0.0091 15.9 2.1 0.45 10.4 0.0 2.8 3 0 0 3 3 2 1 AAA ATPase domain SMC_N PF02463.14 KUM58278.1 - 0.021 14.0 0.0 2.1 7.4 0.0 2.9 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KUM58278.1 - 0.028 14.5 0.1 8.5 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KUM58278.1 - 0.033 13.9 0.2 7.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain MMR_HSR1 PF01926.18 KUM58278.1 - 0.062 13.2 0.0 15 5.5 0.0 3.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase Miro PF08477.8 KUM58278.1 - 0.069 13.6 0.0 11 6.5 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein NACHT PF05729.7 KUM58278.1 - 0.071 12.7 2.0 11 5.6 0.0 3.0 3 0 0 3 3 3 0 NACHT domain Arch_ATPase PF01637.13 KUM58278.1 - 0.11 12.2 0.0 3.9 7.1 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_17 PF13207.1 KUM58278.1 - 0.12 13.1 0.0 2.4 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KUM58278.1 - 0.14 12.0 0.1 14 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 KUM58278.1 - 0.25 10.8 0.1 17 4.8 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.1 KUM58278.1 - 0.38 11.0 0.0 1.5 9.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KUM58278.1 - 0.4 10.2 1.7 2.4 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Glyco_transf_90 PF05686.7 KUM58279.1 - 2.2e-14 52.9 0.0 3e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Aldose_epim PF01263.15 KUM58280.1 - 5e-49 167.0 0.0 8e-49 166.3 0.0 1.2 1 1 0 1 1 1 1 Aldose 1-epimerase DUF3596 PF12167.3 KUM58280.1 - 0.026 14.0 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3596) Fer2_4 PF13510.1 KUM58280.1 - 0.057 13.2 0.0 0.53 10.1 0.0 2.2 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain SH3BGR PF04908.10 KUM58281.1 - 0.00026 20.8 0.0 0.00098 19.0 0.0 2.1 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein SPO11_like PF03533.9 KUM58282.1 - 0.018 14.9 1.0 0.5 10.2 0.4 2.3 2 0 0 2 2 2 0 SPO11 homologue G-patch PF01585.18 KUM58283.1 - 9.6e-12 44.5 0.5 1.6e-11 43.7 0.4 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KUM58283.1 - 8.9e-08 31.8 0.1 2.5e-07 30.4 0.1 1.7 1 0 0 1 1 1 1 DExH-box splicing factor binding site zf-RanBP PF00641.13 KUM58283.1 - 1.7e-07 30.1 4.7 3.6e-07 29.1 3.3 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 KUM58283.1 - 1.7e-07 30.7 0.0 0.0087 15.6 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM58283.1 - 7e-06 25.9 0.1 0.12 12.4 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RED_N PF07808.8 KUM58283.1 - 0.0021 17.3 1.4 0.0049 16.1 1.0 1.6 1 0 0 1 1 1 1 RED-like protein N-terminal region DUF3433 PF11915.3 KUM58285.1 - 8.6e-37 125.1 19.9 1.3e-28 98.9 1.7 3.9 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) SUR7 PF06687.7 KUM58286.1 - 3.2e-29 102.0 14.0 4e-29 101.6 9.7 1.1 1 0 0 1 1 1 1 SUR7/PalI family FAD_binding_4 PF01565.18 KUM58288.1 - 2.4e-07 30.3 4.8 2.4e-07 30.3 3.3 1.7 1 1 1 2 2 2 1 FAD binding domain YjbE PF11106.3 KUM58288.1 - 2.3 8.2 6.9 0.35 10.8 2.1 1.8 2 1 0 2 2 2 0 Exopolysaccharide production protein YjbE DUF1479 PF07350.7 KUM58289.1 - 8.1e-144 479.1 0.3 9.8e-123 409.6 0.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1479) PhyH PF05721.8 KUM58289.1 - 0.08 12.9 0.1 0.38 10.7 0.1 2.0 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) MoaE PF02391.12 KUM58290.1 - 3.1e-29 101.1 0.0 3.8e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 MoaE protein Alpha-amylase PF00128.19 KUM58291.1 - 5.4e-94 315.1 4.3 9.3e-94 314.3 3.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Peptidase_S10 PF00450.17 KUM58292.1 - 2.1e-64 218.2 2.5 5.9e-64 216.7 1.7 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase PhyH PF05721.8 KUM58293.1 - 3.1e-12 46.9 0.0 7.4e-11 42.4 0.0 2.1 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) ETF PF01012.16 KUM58294.1 - 1.3e-36 125.8 0.2 1.6e-36 125.4 0.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Ribosomal_L20 PF00453.13 KUM58294.1 - 0.041 13.8 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L20 Pkinase PF00069.20 KUM58295.1 - 3.5e-12 46.0 0.0 5.2e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM58295.1 - 1.8e-06 27.2 0.0 3.8e-06 26.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase DUF500 PF04366.7 KUM58296.1 - 9.1e-45 151.1 0.0 1.9e-44 150.1 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) LysM PF01476.15 KUM58298.1 - 0.00027 20.7 0.1 0.00044 20.0 0.0 1.3 1 0 0 1 1 1 1 LysM domain PARP PF00644.15 KUM58299.1 - 4.5e-33 114.4 0.5 1.1e-31 109.9 0.0 2.8 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain BTB PF00651.26 KUM58300.1 - 1e-05 25.5 0.0 2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF3328 PF11807.3 KUM58301.1 - 3.4e-38 131.5 1.1 4.1e-38 131.2 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) PhyH PF05721.8 KUM58302.1 - 1.3e-09 38.3 0.1 2.6e-09 37.4 0.1 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 KUM58302.1 - 7e-08 31.3 0.2 0.033 12.6 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) PhyH PF05721.8 KUM58303.1 - 1.3e-22 80.9 0.0 2.1e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PBP PF01161.15 KUM58304.1 - 5.7e-17 61.9 0.1 6.6e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Fungal_trans_2 PF11951.3 KUM58305.1 - 5.7e-30 104.1 2.6 9.3e-30 103.4 1.8 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-met PF12874.2 KUM58306.1 - 4.2e-17 61.6 48.4 4e-06 26.8 0.4 7.6 9 0 0 9 9 9 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KUM58306.1 - 1.5e-15 56.8 42.7 9.6e-05 22.4 1.1 7.6 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KUM58306.1 - 7.6e-13 48.4 41.7 0.0064 16.5 0.6 7.9 2 2 6 8 8 8 6 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 KUM58306.1 - 1.4e-10 40.7 41.2 0.014 15.7 0.2 8.3 7 1 0 7 7 7 6 C2H2-type zinc finger zf-C2H2 PF00096.21 KUM58306.1 - 6.4e-09 35.6 48.1 0.059 13.7 0.1 8.4 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KUM58306.1 - 0.016 15.4 34.9 0.26 11.6 0.2 8.2 8 0 0 8 8 8 0 Zinc-finger double domain zf-RING_3 PF14369.1 KUM58306.1 - 0.073 13.0 0.2 0.073 13.0 0.2 5.1 5 0 0 5 5 5 0 zinc-finger Ribosomal_L31 PF01197.13 KUM58306.1 - 3.9 7.5 6.1 3 7.8 0.1 3.4 1 1 1 2 2 2 0 Ribosomal protein L31 E1_DerP2_DerF2 PF02221.10 KUM58307.1 - 0.02 15.1 0.0 0.19 11.9 0.0 2.2 2 0 0 2 2 2 0 ML domain tRNA_lig_CPD PF08302.6 KUM58308.1 - 1.8e-91 305.9 0.0 2.7e-91 305.3 0.0 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.5 KUM58308.1 - 1.6e-78 263.1 0.1 3.3e-78 262.1 0.1 1.6 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 KUM58308.1 - 3.7e-49 166.8 0.0 6.8e-49 165.9 0.0 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_33 PF13671.1 KUM58308.1 - 0.035 13.9 0.1 0.13 12.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain Gene66 PF02053.10 KUM58308.1 - 0.058 12.8 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Gene 66 (IR5) protein PAP2 PF01569.16 KUM58309.1 - 7.7e-22 77.3 2.5 2e-21 76.0 1.8 1.6 1 0 0 1 1 1 1 PAP2 superfamily DUF2975 PF11188.3 KUM58309.1 - 0.32 10.7 11.1 1.1 8.9 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) TctB PF07331.6 KUM58309.1 - 1.2 8.8 7.0 2.3 7.8 1.0 3.0 3 0 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family Abhydrolase_4 PF08386.5 KUM58310.1 - 5.6e-14 51.8 0.0 1.4e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KUM58310.1 - 7.8e-10 38.6 0.0 1.5e-09 37.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KUM58310.1 - 1.2e-08 35.1 6.0 1.2e-08 35.1 4.2 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM58310.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Mod_r PF07200.8 KUM58311.1 - 3.9e-11 43.0 2.2 5.5e-11 42.5 1.6 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein RcbX PF02341.10 KUM58311.1 - 0.022 14.8 0.1 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 RbcX protein Fib_alpha PF08702.5 KUM58311.1 - 0.053 13.6 1.0 0.12 12.4 0.5 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Ank_2 PF12796.2 KUM58313.1 - 1.9e-91 300.5 5.5 7.1e-20 71.1 0.3 6.5 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KUM58313.1 - 3.9e-89 288.3 11.7 4.8e-09 35.5 0.0 12.7 12 0 0 12 12 12 11 Ankyrin repeat Ank_3 PF13606.1 KUM58313.1 - 3.2e-62 200.2 8.8 1.9e-06 27.5 0.0 12.9 12 0 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.1 KUM58313.1 - 3.9e-61 202.4 13.9 1.5e-12 47.6 0.0 9.2 3 2 6 10 10 10 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM58313.1 - 4.3e-54 179.3 13.1 3.5e-07 30.2 0.0 10.6 3 3 8 11 11 11 11 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 KUM58313.1 - 2.8e-11 42.8 2.1 2.7e-10 39.6 1.5 2.3 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_22 PF13401.1 KUM58313.1 - 0.0099 16.0 0.0 0.031 14.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mago_nashi PF02792.9 KUM58313.1 - 0.078 12.6 0.0 4.9 6.8 0.0 2.7 2 0 0 2 2 2 0 Mago nashi protein Ank_4 PF13637.1 KUM58314.1 - 2.9e-12 46.7 0.8 2.4e-07 31.0 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM58314.1 - 6.2e-12 45.3 0.1 1.3e-09 37.9 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM58314.1 - 1e-05 25.2 0.6 0.00015 21.6 0.1 3.0 3 1 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 KUM58314.1 - 1.1e-05 25.6 0.1 5e-05 23.5 0.1 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KUM58314.1 - 1.3e-05 24.7 0.6 0.00051 19.7 0.1 2.9 2 1 0 2 2 2 1 Ankyrin repeat YejG PF13989.1 KUM58314.1 - 0.0021 18.1 0.0 0.0037 17.3 0.0 1.4 1 0 0 1 1 1 1 YejG-like protein TipAS PF07739.8 KUM58314.1 - 0.066 13.5 0.5 5.8 7.2 0.0 2.2 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Got1 PF04178.7 KUM58316.1 - 6.3e-33 113.3 15.6 8.7e-33 112.9 10.8 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Peptidase_M50 PF02163.17 KUM58316.1 - 0.0035 16.3 0.2 0.0083 15.1 0.1 1.7 1 1 0 1 1 1 1 Peptidase family M50 HLH PF00010.21 KUM58317.1 - 1.7e-12 46.8 0.0 6.6e-12 44.9 0.0 2.0 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain RTA1 PF04479.8 KUM58319.1 - 3.6e-39 134.5 11.1 5.7e-39 133.9 7.7 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF373 PF04123.8 KUM58319.1 - 0.19 10.7 6.0 0.1 11.5 2.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF373) stn_TNFRSF12A PF12191.3 KUM58319.1 - 0.57 10.2 3.4 24 4.9 0.0 3.0 3 1 1 4 4 4 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain OST3_OST6 PF04756.8 KUM58319.1 - 1.8 8.1 12.0 1.5 8.3 1.2 3.5 2 1 1 4 4 4 0 OST3 / OST6 family adh_short_C2 PF13561.1 KUM58320.1 - 6.9e-27 94.7 0.0 8.1e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KUM58320.1 - 2.1e-26 92.8 2.2 2.7e-26 92.4 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM58320.1 - 1.2e-12 47.8 0.6 1.6e-12 47.4 0.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM58320.1 - 0.0008 18.9 0.1 0.0014 18.0 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KUM58320.1 - 0.036 12.9 0.0 0.047 12.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DFP PF04127.10 KUM58320.1 - 0.099 12.2 0.1 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NusB PF01029.13 KUM58320.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 NusB family AAA_12 PF13087.1 KUM58321.1 - 2.3e-26 92.4 0.0 3.9e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KUM58321.1 - 4.1e-23 82.1 0.0 7.8e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KUM58321.1 - 2.4e-09 36.8 0.1 1.9e-08 33.9 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KUM58321.1 - 6.9e-07 29.0 0.0 0.0016 18.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 KUM58321.1 - 8.4e-05 22.4 0.0 0.00032 20.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KUM58321.1 - 0.00039 20.0 0.1 0.077 12.4 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 KUM58321.1 - 0.002 17.5 0.0 0.0045 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KUM58321.1 - 0.005 16.8 0.0 0.019 14.9 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KUM58321.1 - 0.0073 16.4 0.0 0.028 14.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain Ring_hydroxyl_B PF00866.13 KUM58321.1 - 0.017 14.8 0.1 0.032 13.9 0.1 1.4 1 0 0 1 1 1 0 Ring hydroxylating beta subunit DEAD PF00270.24 KUM58321.1 - 0.019 14.4 0.0 0.054 12.9 0.0 1.8 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA PF00004.24 KUM58321.1 - 0.02 15.1 0.0 0.069 13.3 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KUM58321.1 - 0.025 15.3 0.0 1.3 9.8 0.0 3.4 3 1 1 4 4 4 0 AAA domain AAA_5 PF07728.9 KUM58321.1 - 0.025 14.2 0.0 0.48 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 KUM58321.1 - 0.026 13.4 0.6 0.055 12.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.10 KUM58321.1 - 0.029 13.2 0.2 0.26 10.1 0.0 2.4 3 0 0 3 3 3 0 DnaB-like helicase C terminal domain Zeta_toxin PF06414.7 KUM58321.1 - 0.04 13.0 0.0 0.1 11.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin UvrD-helicase PF00580.16 KUM58321.1 - 0.044 13.0 0.0 0.1 11.8 0.0 1.6 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain NB-ARC PF00931.17 KUM58321.1 - 0.064 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Arch_ATPase PF01637.13 KUM58321.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase UvrD_C_2 PF13538.1 KUM58321.1 - 0.1 12.7 0.1 0.36 10.9 0.0 2.0 2 0 0 2 2 1 0 UvrD-like helicase C-terminal domain PIF1 PF05970.9 KUM58321.1 - 0.11 11.4 0.0 4.3 6.1 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase RNA_helicase PF00910.17 KUM58321.1 - 0.17 12.0 0.0 0.69 10.1 0.0 2.1 2 0 0 2 2 1 0 RNA helicase 4HBT PF03061.17 KUM58322.1 - 3e-14 52.8 0.1 4.5e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 KUM58322.1 - 0.0015 18.3 0.0 0.0016 18.2 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.1 KUM58322.1 - 0.072 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Ada_Zn_binding PF02805.11 KUM58325.1 - 3.4e-29 100.2 4.5 5.4e-29 99.5 3.1 1.3 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 KUM58325.1 - 3.5e-08 33.0 0.0 7.6e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 KUM58325.1 - 0.00032 20.7 0.0 0.00066 19.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 KUM58325.1 - 0.055 13.6 0.1 0.37 11.0 0.0 2.4 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.1 KUM58325.1 - 0.073 12.7 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain TGT PF01702.13 KUM58327.1 - 1.3e-85 286.5 0.0 1.5e-85 286.3 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Thymidylat_synt PF00303.14 KUM58328.1 - 1.7e-109 365.0 0.0 1.9e-109 364.8 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase MFS_1 PF07690.11 KUM58329.1 - 1.7e-32 112.5 28.7 2.2e-32 112.1 19.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM58329.1 - 4.8e-06 25.4 18.3 0.0011 17.6 0.0 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 KUM58329.1 - 0.017 14.8 0.6 0.091 12.5 0.0 2.3 2 0 0 2 2 2 0 MFS_1 like family DUF202 PF02656.10 KUM58329.1 - 0.87 9.8 9.2 2.1 8.6 0.1 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF202) Aldo_ket_red PF00248.16 KUM58330.1 - 4.5e-65 219.2 0.0 5.1e-65 219.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.13 KUM58331.1 - 4.7e-06 26.4 9.9 1e-05 25.3 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KUM58331.1 - 0.00025 19.7 6.6 0.0005 18.7 4.6 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Ldl_recept_a PF00057.13 KUM58331.1 - 0.21 11.5 3.5 0.47 10.3 2.4 1.6 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A zf-AN1 PF01428.11 KUM58332.1 - 2.2e-23 81.8 22.3 2.2e-12 46.6 4.4 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 KUM58332.1 - 0.0037 17.1 5.9 0.0037 17.1 4.1 2.6 2 1 0 2 2 2 1 IBR domain Transp_Tc5_C PF04236.10 KUM58332.1 - 0.022 14.9 14.3 0.54 10.5 2.1 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain DDE_Tnp_IS66 PF03050.9 KUM58332.1 - 0.072 12.3 0.2 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 Transposase IS66 family PhnA_Zn_Ribbon PF08274.7 KUM58332.1 - 0.37 10.6 5.1 6.5 6.6 0.6 2.7 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zinc_ribbon_5 PF13719.1 KUM58332.1 - 1.1 8.9 6.9 3.3 7.3 0.8 2.8 2 0 0 2 2 2 0 zinc-ribbon domain C1_4 PF07975.7 KUM58332.1 - 5.2 7.1 21.3 12 5.9 3.9 3.3 2 2 0 2 2 2 0 TFIIH C1-like domain zinc_ribbon_4 PF13717.1 KUM58332.1 - 7.3 6.3 9.3 3.5 7.3 0.7 2.8 2 0 0 2 2 2 0 zinc-ribbon domain MFS_1 PF07690.11 KUM58333.1 - 3.9e-26 91.6 33.8 5.6e-26 91.0 23.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily efThoc1 PF11957.3 KUM58334.1 - 1.6e-175 584.3 3.9 2.5e-175 583.7 2.7 1.2 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor NADH_oxidored PF08040.6 KUM58334.1 - 0.11 12.0 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 MNLL subunit Tfb2 PF03849.9 KUM58336.1 - 5.2e-139 462.9 0.0 1.7e-138 461.2 0.0 1.7 2 0 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 KUM58336.1 - 2.3e-05 24.1 0.1 0.00017 21.3 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SinI PF08671.5 KUM58336.1 - 0.0057 16.0 0.0 0.063 12.7 0.0 2.3 2 0 0 2 2 2 1 Anti-repressor SinI Paramecium_SA PF01508.11 KUM58337.1 - 0.0028 17.8 11.1 0.11 12.7 1.7 2.1 2 0 0 2 2 2 2 Paramecium surface antigen domain ANATO PF01821.13 KUM58337.1 - 0.023 14.8 1.2 0.68 10.1 0.2 3.0 2 1 0 2 2 2 0 Anaphylotoxin-like domain Pectate_lyase_3 PF12708.2 KUM58338.1 - 2.1e-91 306.0 16.2 9.9e-71 238.4 6.7 2.6 2 1 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KUM58338.1 - 4.5e-06 26.0 1.1 0.04 13.3 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 KUM58338.1 - 0.024 14.4 10.4 0.012 15.4 4.6 2.5 2 1 0 2 2 2 0 Right handed beta helix region Aminotran_1_2 PF00155.16 KUM58339.1 - 1.6e-17 63.4 0.0 2.2e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KUM58339.1 - 0.021 13.4 0.0 0.41 9.1 0.0 2.1 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase AflR PF08493.5 KUM58340.1 - 3.1e-09 36.2 0.3 4.5e-09 35.7 0.2 1.3 1 0 0 1 1 1 1 Aflatoxin regulatory protein Fungal_trans_2 PF11951.3 KUM58341.1 - 5.8e-09 35.0 1.4 1.7e-08 33.5 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM58341.1 - 1.4e-06 28.0 9.2 2.7e-06 27.1 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.8 KUM58342.1 - 2.5e-63 213.6 6.4 3.6e-63 213.0 4.4 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF267 PF03268.9 KUM58342.1 - 0.022 13.6 0.0 0.069 11.9 0.0 1.8 1 1 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF267 DUF4131 PF13567.1 KUM58342.1 - 0.047 13.0 2.4 0.24 10.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Pyr_redox_2 PF07992.9 KUM58343.1 - 8.8e-26 91.0 0.0 1.5e-19 70.7 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KUM58343.1 - 1.7e-09 37.9 0.0 1.3e-08 35.0 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KUM58343.1 - 0.0015 18.5 0.0 0.6 10.1 0.0 4.0 2 1 2 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase HSP20 PF00011.16 KUM58344.1 - 2.4e-07 30.5 0.1 3.8e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family NLPC_P60 PF00877.14 KUM58346.1 - 5.1e-19 68.0 0.0 1e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 NlpC/P60 family SH3_3 PF08239.6 KUM58346.1 - 0.002 18.2 0.3 0.0039 17.3 0.2 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain DUF1175 PF06672.6 KUM58346.1 - 0.0047 16.2 0.0 0.53 9.5 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1175) Amidase_5 PF05382.8 KUM58346.1 - 0.099 12.2 5.5 0.036 13.6 0.4 2.5 1 1 1 2 2 2 0 Bacteriophage peptidoglycan hydrolase Aa_trans PF01490.13 KUM58347.1 - 3.1e-20 72.0 36.9 3.7e-20 71.8 25.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein NADH_Oxid_Nqo15 PF11497.3 KUM58347.1 - 0.021 14.5 0.1 1.5 8.5 0.0 2.5 2 0 0 2 2 2 0 NADH-quinone oxidoreductase chain 15 IBV_3C PF03620.8 KUM58347.1 - 0.065 13.1 1.3 0.33 10.8 0.2 2.7 2 0 0 2 2 2 0 IBV 3C protein Methyltransf_2 PF00891.13 KUM58348.1 - 1.5e-24 86.5 0.1 6.6e-24 84.4 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase Amidase PF01425.16 KUM58349.1 - 4.3e-83 279.6 0.0 5e-83 279.3 0.0 1.0 1 0 0 1 1 1 1 Amidase Ribosomal_L16 PF00252.13 KUM58350.1 - 8.5e-30 103.2 0.2 1.1e-29 102.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e S6PP_C PF08472.5 KUM58351.1 - 0.041 13.5 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal Ank_2 PF12796.2 KUM58352.1 - 1.4e-56 188.7 2.9 1.2e-19 70.4 0.1 4.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KUM58352.1 - 2.9e-52 171.9 9.6 2.4e-08 33.3 0.1 8.9 8 1 1 9 9 9 6 Ankyrin repeat Ank_3 PF13606.1 KUM58352.1 - 2e-40 132.7 8.4 1.4e-05 24.8 0.0 9.5 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.1 KUM58352.1 - 4.9e-38 128.8 11.1 3.3e-13 49.7 0.0 6.9 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM58352.1 - 3.3e-37 125.6 9.7 2.1e-10 40.4 0.3 7.6 3 2 4 7 7 7 6 Ankyrin repeats (many copies) CorA PF01544.13 KUM58352.1 - 1.7e-12 47.0 0.7 4e-12 45.7 0.5 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein GLE1 PF07817.8 KUM58352.1 - 0.17 10.7 0.6 0.32 9.8 0.4 1.4 1 0 0 1 1 1 0 GLE1-like protein Neur_chan_memb PF02932.11 KUM58352.1 - 0.96 9.2 2.6 2.2 8.1 1.8 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Arrestin_C PF02752.17 KUM58353.1 - 6.1e-09 36.0 0.1 6.5e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KUM58353.1 - 0.0031 17.3 0.1 0.069 12.9 0.0 2.8 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain YchF-GTPase_C PF06071.8 KUM58354.1 - 4.8e-36 122.4 0.1 1.1e-35 121.2 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 KUM58354.1 - 1.4e-16 60.5 0.0 2.6e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KUM58354.1 - 8.8e-07 28.3 0.0 1.6e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF2855 PF11017.3 KUM58356.1 - 2.4e-69 233.9 0.0 6.8e-69 232.4 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2855) Chitin_synth_2 PF03142.10 KUM58357.1 - 8.6e-294 974.8 0.2 1.1e-293 974.4 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 KUM58357.1 - 1.2e-16 61.0 1.5 4.1e-16 59.2 1.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KUM58357.1 - 6.3e-13 49.0 0.0 1.2e-11 44.8 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 KUM58357.1 - 2.6e-10 39.9 0.1 3.9e-06 26.5 0.0 2.5 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 KUM58357.1 - 0.0001 22.0 0.0 0.0047 16.6 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KUM58357.1 - 0.00046 19.5 0.1 0.0019 17.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 WD40 PF00400.27 KUM58359.1 - 7.6e-09 35.1 0.7 6.6e-08 32.1 0.1 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF2415 PF10313.4 KUM58359.1 - 0.018 14.7 0.0 0.053 13.2 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) Sel1 PF08238.7 KUM58362.1 - 1.8e-38 130.1 20.9 1.9e-06 28.3 0.0 7.5 7 0 0 7 7 7 7 Sel1 repeat COesterase PF00135.23 KUM58363.1 - 6.8e-15 54.7 0.0 7.5e-15 54.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.23 KUM58364.1 - 3.7e-29 101.8 0.0 4.6e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Fungal_trans PF04082.13 KUM58365.1 - 2e-10 39.9 0.3 7.9e-10 38.0 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Tis11B_N PF04553.7 KUM58365.1 - 0.06 13.5 2.0 0.13 12.4 1.4 1.5 1 0 0 1 1 1 0 Tis11B like protein, N terminus zf-C2H2_4 PF13894.1 KUM58366.1 - 0.00014 21.9 4.3 0.00026 21.0 2.9 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 KUM58366.1 - 0.0041 17.3 3.6 0.0074 16.5 2.5 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-Di19 PF05605.7 KUM58366.1 - 0.0086 16.1 0.6 0.014 15.5 0.4 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 KUM58366.1 - 0.016 15.3 1.0 0.025 14.7 0.7 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KUM58366.1 - 0.029 14.1 0.4 0.049 13.3 0.3 1.3 1 0 0 1 1 1 0 BED zinc finger zf-H2C2_2 PF13465.1 KUM58366.1 - 0.1 12.9 0.6 0.1 12.9 0.4 2.3 2 0 0 2 2 2 0 Zinc-finger double domain AA_permease_2 PF13520.1 KUM58367.1 - 9.9e-64 215.4 46.0 1.2e-63 215.1 31.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM58367.1 - 1.5e-17 63.0 35.6 2.3e-17 62.5 24.7 1.2 1 0 0 1 1 1 1 Amino acid permease SUR7 PF06687.7 KUM58370.1 - 1.3e-24 86.9 6.9 1.6e-24 86.6 4.8 1.0 1 0 0 1 1 1 1 SUR7/PalI family DUF4282 PF14110.1 KUM58370.1 - 0.84 9.8 12.8 0.06 13.5 2.8 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4282) zf-DHHC PF01529.15 KUM58370.1 - 4.6 6.6 5.4 23 4.3 0.2 2.3 2 1 0 2 2 2 0 DHHC palmitoyltransferase Mannitol_dh_C PF08125.8 KUM58371.1 - 1.5e-47 161.8 0.0 2.1e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 KUM58371.1 - 4.4e-18 65.6 1.3 7.6e-18 64.9 0.1 1.8 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain B12-binding PF02310.14 KUM58371.1 - 0.0047 16.8 0.1 1.4 8.7 0.0 2.4 2 0 0 2 2 2 2 B12 binding domain 3HCDH_N PF02737.13 KUM58371.1 - 0.021 14.5 0.5 0.042 13.5 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KUM58371.1 - 0.03 13.7 0.2 0.065 12.6 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pkinase PF00069.20 KUM58372.1 - 9.7e-65 218.2 0.0 1.1e-64 218.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM58372.1 - 2.5e-28 98.8 0.0 3.2e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KUM58372.1 - 8.3e-10 39.0 0.2 1.6e-09 38.1 0.2 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KUM58372.1 - 0.00051 19.0 0.0 0.00068 18.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF1907 PF08925.6 KUM58373.1 - 2e-85 286.3 0.0 2.5e-85 286.0 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) ECH PF00378.15 KUM58374.1 - 1.3e-44 152.2 0.2 1.8e-44 151.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DoxD PF04173.8 KUM58374.1 - 0.064 12.9 2.8 0.067 12.8 0.0 1.9 2 0 0 2 2 2 0 TQO small subunit DoxD SWIRM PF04433.12 KUM58375.1 - 3.7e-15 55.8 0.0 9.1e-15 54.5 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 KUM58375.1 - 1.6e-11 43.5 4.6 2.7e-11 42.8 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 KUM58375.1 - 2.6e-08 33.7 0.0 7.3e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Thioredoxin PF00085.15 KUM58376.1 - 1.3e-36 124.4 0.0 1.3e-23 82.6 0.0 4.3 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 KUM58376.1 - 5e-14 52.5 0.0 1.1e-05 25.3 0.0 4.4 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KUM58376.1 - 4.4e-06 26.8 0.8 0.037 14.2 0.1 4.3 3 2 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KUM58376.1 - 4.8e-05 23.3 0.1 0.083 13.0 0.0 3.8 3 0 0 3 3 3 1 Thioredoxin-like HyaE PF07449.6 KUM58376.1 - 0.00012 21.8 0.0 0.13 12.1 0.0 2.8 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.16 KUM58376.1 - 0.00066 19.3 0.2 2.6 7.7 0.0 3.2 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_3 PF13192.1 KUM58376.1 - 0.0034 17.1 0.1 0.55 10.0 0.0 2.8 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_7 PF13899.1 KUM58376.1 - 0.03 14.3 1.0 0.14 12.2 0.1 2.5 3 0 0 3 3 3 0 Thioredoxin-like QCR10 PF09796.4 KUM58377.1 - 9.9e-24 82.7 0.0 1.4e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Coatomer_WDAD PF04053.9 KUM58378.1 - 1.6e-168 561.0 0.0 7.8e-168 558.8 0.0 1.9 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 KUM58378.1 - 9.4e-48 158.4 7.7 2.1e-10 40.0 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 KUM58378.1 - 6.1e-05 21.3 0.2 0.058 11.5 0.0 3.4 3 0 0 3 3 3 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 KUM58378.1 - 0.0019 17.9 0.0 2.3 8.0 0.0 3.7 1 1 2 3 3 3 2 Ciliary BBSome complex subunit 2, middle region ETC_C1_NDUFA5 PF04716.9 KUM58379.1 - 2.4e-21 75.0 0.0 2.4e-21 75.0 0.0 2.1 2 0 0 2 2 2 1 ETC complex I subunit conserved region DUF3121 PF11319.3 KUM58379.1 - 0.041 13.3 0.2 0.074 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3121) Ku_PK_bind PF08785.6 KUM58379.1 - 0.092 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Ku C terminal domain like RF-1 PF00472.15 KUM58380.1 - 1.1e-15 57.3 2.1 1.7e-15 56.8 1.5 1.3 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.4 KUM58380.1 - 0.0036 17.3 1.2 0.011 15.8 0.5 1.9 1 1 1 2 2 2 1 Mitochondrial ribosomal subunit protein RRM_1 PF00076.17 KUM58381.1 - 3e-05 23.5 0.0 5.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM58381.1 - 0.0027 17.6 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Hairy_orange PF07527.8 KUM58381.1 - 0.19 11.4 0.5 11 5.7 0.0 2.8 2 0 0 2 2 2 0 Hairy Orange SOG2 PF10428.4 KUM58381.1 - 0.25 9.9 1.7 0.46 9.0 1.2 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein SYS1 PF09801.4 KUM58382.1 - 7.9e-30 103.7 1.1 9.1e-30 103.5 0.7 1.1 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network COX6B PF02297.12 KUM58384.1 - 1.3e-23 82.7 4.3 1.8e-23 82.3 3.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 KUM58384.1 - 0.0099 15.9 1.2 0.015 15.3 0.8 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 XH PF03469.9 KUM58384.1 - 0.087 12.4 3.2 0.11 12.1 2.2 1.1 1 0 0 1 1 1 0 XH domain CPSF100_C PF13299.1 KUM58385.1 - 7.5e-44 149.7 0.5 1.2e-43 149.0 0.0 1.7 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 KUM58385.1 - 1.9e-27 95.6 0.0 1.2e-26 93.0 0.0 2.3 3 0 0 3 3 3 1 Beta-Casp domain RMMBL PF07521.7 KUM58385.1 - 0.00026 20.7 0.0 0.00063 19.5 0.0 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 KUM58385.1 - 0.025 14.2 0.4 0.12 12.0 0.3 2.1 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily AA_permease_2 PF13520.1 KUM58386.1 - 4.7e-58 196.7 42.5 5.8e-58 196.4 29.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM58386.1 - 9.2e-22 77.0 37.3 1.2e-21 76.6 25.9 1.0 1 0 0 1 1 1 1 Amino acid permease U3_assoc_6 PF08640.6 KUM58387.1 - 1.4e-29 101.6 2.4 1.7e-29 101.3 0.6 1.9 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 Suf PF05843.9 KUM58387.1 - 2.9e-05 23.9 0.2 0.019 14.7 0.0 3.0 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_15 PF13429.1 KUM58387.1 - 5.5e-05 22.3 0.1 0.0044 16.1 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KUM58387.1 - 9.1e-05 22.7 0.4 0.1 13.2 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat NRDE-2 PF08424.5 KUM58387.1 - 0.057 12.2 0.0 0.1 11.4 0.0 1.5 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference TPR_11 PF13414.1 KUM58387.1 - 0.1 12.2 0.0 0.28 10.8 0.0 1.8 1 1 0 1 1 1 0 TPR repeat Frag1 PF10277.4 KUM58388.1 - 2.5e-44 151.3 8.0 2.5e-44 151.3 5.5 2.6 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family MIP-T3 PF10243.4 KUM58389.1 - 4 5.8 50.3 0.22 9.9 23.0 2.0 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Sec23_trunk PF04811.10 KUM58391.1 - 1.4e-53 181.7 0.0 3.3e-53 180.5 0.0 1.6 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KUM58391.1 - 1.4e-25 88.7 0.0 2.5e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KUM58391.1 - 1.1e-17 64.2 0.0 2.1e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KUM58391.1 - 2e-16 59.2 5.6 3.8e-16 58.3 3.9 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KUM58391.1 - 4.9e-08 32.5 0.0 9.2e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat SLS PF14611.1 KUM58391.1 - 0.16 11.3 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator DUF1678 PF07913.6 KUM58391.1 - 0.2 11.1 0.0 0.54 9.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) ABC2_membrane PF01061.19 KUM58393.1 - 1.5e-50 171.2 30.7 4.1e-30 104.5 6.1 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 KUM58393.1 - 1.6e-50 170.9 0.0 4.7e-25 88.4 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KUM58393.1 - 1.1e-17 64.8 2.4 9.9e-07 28.9 0.2 4.3 3 1 0 4 4 4 3 AAA domain AAA_16 PF13191.1 KUM58393.1 - 1.6e-11 44.5 0.2 9.3e-05 22.4 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 KUM58393.1 - 2.9e-09 36.2 0.7 0.0013 17.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KUM58393.1 - 1.7e-08 35.0 0.2 0.00025 21.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KUM58393.1 - 5e-08 32.4 1.7 0.00038 19.7 0.2 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KUM58393.1 - 3.2e-07 29.9 0.0 0.019 14.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KUM58393.1 - 4e-07 30.2 0.1 0.029 14.4 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KUM58393.1 - 5.1e-07 30.5 0.0 0.031 15.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KUM58393.1 - 5.5e-07 29.0 1.8 0.01 15.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_10 PF12846.2 KUM58393.1 - 5.4e-06 26.0 0.9 0.065 12.6 0.1 2.4 2 0 0 2 2 2 2 AAA-like domain NACHT PF05729.7 KUM58393.1 - 6.8e-06 25.8 0.0 0.026 14.1 0.0 2.5 2 0 0 2 2 2 2 NACHT domain Arch_ATPase PF01637.13 KUM58393.1 - 1.5e-05 24.7 0.0 0.019 14.6 0.0 2.3 2 0 0 2 2 2 2 Archaeal ATPase AAA_15 PF13175.1 KUM58393.1 - 1.6e-05 24.1 0.0 0.94 8.4 0.0 3.9 4 0 0 4 4 4 1 AAA ATPase domain T2SE PF00437.15 KUM58393.1 - 1.7e-05 23.8 0.3 0.019 13.8 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein cobW PF02492.14 KUM58393.1 - 5.6e-05 22.6 0.5 0.16 11.4 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 KUM58393.1 - 8e-05 22.2 0.1 0.37 10.2 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_28 PF13521.1 KUM58393.1 - 0.00011 22.2 0.0 0.61 10.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.1 KUM58393.1 - 0.00014 21.7 0.0 0.19 11.6 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.1 KUM58393.1 - 0.00014 21.4 0.3 0.44 10.0 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 KUM58393.1 - 0.00016 21.3 0.1 0.32 10.7 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain MobB PF03205.9 KUM58393.1 - 0.00022 20.9 0.2 0.78 9.4 0.0 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KUM58393.1 - 0.00031 21.0 0.4 0.44 10.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.18 KUM58393.1 - 0.00033 20.5 0.4 0.34 10.8 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.24 KUM58393.1 - 0.00033 20.8 0.0 0.62 10.2 0.0 2.8 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KUM58393.1 - 0.00036 20.6 0.0 0.83 9.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.9 KUM58393.1 - 0.00049 19.8 0.0 0.26 10.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) Miro PF08477.8 KUM58393.1 - 0.0014 19.1 0.1 1.2 9.6 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein Zeta_toxin PF06414.7 KUM58393.1 - 0.002 17.2 0.0 1.8 7.6 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.1 KUM58393.1 - 0.0035 16.9 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 KUM58393.1 - 0.0044 16.9 0.8 2.8 7.9 0.0 3.7 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit KAP_NTPase PF07693.9 KUM58393.1 - 0.0079 15.2 0.0 1.5 7.7 0.0 2.2 2 0 0 2 2 2 1 KAP family P-loop domain UPF0079 PF02367.12 KUM58393.1 - 0.0083 15.7 0.1 1.9 8.1 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 KUM58393.1 - 0.012 15.2 0.1 6.6 6.4 0.0 2.7 3 0 0 3 3 2 0 NTPase PduV-EutP PF10662.4 KUM58393.1 - 0.015 14.7 0.3 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 KUM58393.1 - 0.017 14.3 0.2 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 KUM58393.1 - 0.02 14.7 0.0 3.2 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 KUM58393.1 - 0.023 14.2 0.0 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.12 KUM58393.1 - 0.037 13.8 0.5 1.2 8.9 0.3 2.6 3 0 0 3 3 2 0 Domain of unknown function DUF87 ATP_bind_1 PF03029.12 KUM58393.1 - 0.043 13.3 0.1 6.3 6.2 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Pox_A32 PF04665.7 KUM58393.1 - 0.046 13.0 0.4 4.9 6.3 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein PIF1 PF05970.9 KUM58393.1 - 0.066 12.1 0.1 4.3 6.1 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase PRK PF00485.13 KUM58393.1 - 0.075 12.5 0.3 7.1 6.1 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF2075 PF09848.4 KUM58393.1 - 0.086 11.8 0.1 3.9 6.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 KUM58393.1 - 0.089 12.0 0.1 14 4.8 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_35 PF14516.1 KUM58393.1 - 0.11 11.1 0.2 3 6.3 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain DUF4388 PF14332.1 KUM58393.1 - 0.13 12.1 0.0 0.51 10.2 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4388) IstB_IS21 PF01695.12 KUM58393.1 - 0.13 11.6 0.1 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein Dynamin_N PF00350.18 KUM58393.1 - 0.14 11.9 3.2 3 7.6 0.1 2.6 3 0 0 3 3 2 0 Dynamin family SRP54 PF00448.17 KUM58393.1 - 0.23 10.8 0.5 16 4.8 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Septin PF00735.13 KUM58393.1 - 0.24 10.4 0.1 19 4.1 0.0 2.3 2 0 0 2 2 2 0 Septin NB-ARC PF00931.17 KUM58393.1 - 0.31 9.8 0.0 4.6 6.0 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain Prenyltrans PF00432.16 KUM58394.1 - 5.4e-34 115.4 13.2 3e-07 29.8 0.3 6.4 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KUM58394.1 - 1.8e-23 83.1 0.0 1.9e-16 60.4 0.0 3.3 2 1 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 KUM58394.1 - 2.5e-05 24.2 0.0 0.0053 16.7 0.0 3.5 3 1 0 3 3 3 1 Prenyltransferase-like Pkinase PF00069.20 KUM58395.1 - 2.5e-68 230.0 0.8 2.7e-68 229.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM58395.1 - 1.6e-42 145.3 0.0 2.3e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM58395.1 - 1.1e-09 37.7 0.0 4.5e-08 32.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KUM58395.1 - 0.0016 17.5 0.1 0.0077 15.3 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KUM58395.1 - 0.018 14.7 4.3 1.3 8.7 0.0 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family FNIP PF05725.7 KUM58396.1 - 0.13 12.2 0.6 2.1 8.3 0.0 3.2 5 0 0 5 5 5 0 FNIP Repeat Spo0M PF07070.6 KUM58396.1 - 0.19 11.0 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 SpoOM protein Ank_2 PF12796.2 KUM58400.1 - 1.3e-47 160.0 5.0 4.7e-14 52.4 0.1 5.7 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KUM58400.1 - 1.9e-40 134.6 19.8 2.8e-06 26.8 0.0 10.2 10 1 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.1 KUM58400.1 - 2.5e-34 117.0 9.6 1.2e-07 32.0 0.0 8.1 5 2 3 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM58400.1 - 7.9e-26 89.5 12.9 1.3e-06 28.4 0.4 6.6 3 3 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM58400.1 - 4.2e-24 82.2 14.2 5.5e-05 23.0 0.0 9.3 10 1 0 10 10 10 6 Ankyrin repeat CBFD_NFYB_HMF PF00808.18 KUM58401.1 - 5e-29 100.1 0.6 6.7e-29 99.7 0.4 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KUM58401.1 - 5.7e-07 29.5 0.0 8.7e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 KUM58401.1 - 0.00021 21.0 0.0 0.00033 20.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 KUM58401.1 - 0.00044 19.9 0.0 0.00072 19.2 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated MFS_1 PF07690.11 KUM58402.1 - 1.8e-31 109.1 22.2 1.8e-31 109.1 15.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM58402.1 - 9.9e-10 37.5 13.4 9.9e-10 37.5 9.3 3.2 3 0 0 3 3 3 1 Sugar (and other) transporter Ilm1 PF10311.4 KUM58403.1 - 2.7e-45 153.8 3.0 7.1e-45 152.4 2.1 1.6 1 1 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 CFEM PF05730.6 KUM58404.1 - 1e-11 44.4 13.6 2.7e-11 43.1 9.4 1.7 1 0 0 1 1 1 1 CFEM domain Mucin PF01456.12 KUM58404.1 - 0.15 11.8 26.8 0.26 11.0 18.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Pex14_N PF04695.8 KUM58404.1 - 0.82 9.7 7.0 1.2 9.1 4.9 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DNA_pol_viral_N PF00242.12 KUM58404.1 - 1.7 7.5 6.7 1.7 7.5 4.7 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Aegerolysin PF06355.8 KUM58405.1 - 1.3e-25 89.7 0.3 1.6e-25 89.4 0.2 1.1 1 0 0 1 1 1 1 Aegerolysin DUF3812 PF12757.2 KUM58408.1 - 1.5e-37 128.4 14.9 1.5e-37 128.4 10.3 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3812) Fungal_trans PF04082.13 KUM58410.1 - 1.3e-11 43.9 0.0 2e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM58410.1 - 6.6e-08 32.3 8.9 1.1e-07 31.6 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KUM58411.1 - 6.7e-39 133.5 35.9 1.1e-33 116.4 17.0 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM58411.1 - 1.2e-05 24.1 9.8 1.2e-05 24.1 6.8 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter Metallophos PF00149.23 KUM58412.1 - 2.9e-42 144.3 0.4 4.4e-42 143.7 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase adh_short_C2 PF13561.1 KUM58414.1 - 3.2e-13 50.0 0.0 3.6e-13 49.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KUM58414.1 - 0.0022 17.9 0.1 0.0028 17.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Beta-lactamase PF00144.19 KUM58416.1 - 2.5e-42 145.1 0.0 7.1e-42 143.5 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase Pyr_redox_3 PF13738.1 KUM58417.1 - 1.3e-20 74.3 0.0 2.1e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KUM58417.1 - 9.5e-19 66.9 0.3 2e-15 56.0 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KUM58417.1 - 2.5e-09 36.5 0.0 2e-08 33.5 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KUM58417.1 - 9e-09 35.5 0.0 1.7e-08 34.6 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM58417.1 - 1.2e-08 34.8 0.0 1.9e-06 27.8 0.1 3.1 3 1 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KUM58417.1 - 5.1e-06 25.6 0.6 0.019 13.9 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KUM58417.1 - 0.00094 18.1 0.0 0.005 15.8 0.0 2.1 3 0 0 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.12 KUM58417.1 - 0.0016 17.6 0.1 0.0041 16.2 0.0 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 KUM58417.1 - 0.0028 16.5 0.0 0.0045 15.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 KUM58417.1 - 0.0035 17.1 4.3 8.1 6.2 0.0 4.2 3 1 1 4 4 4 2 FAD-NAD(P)-binding Pyr_redox PF00070.22 KUM58417.1 - 0.0092 16.3 0.1 2 8.8 0.1 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KUM58417.1 - 0.24 9.8 2.2 0.26 9.7 0.0 2.0 3 0 0 3 3 3 0 HI0933-like protein DUF1996 PF09362.5 KUM58418.1 - 5.8e-79 265.0 0.4 9e-79 264.4 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF3472 PF11958.3 KUM58420.1 - 1.1e-12 48.7 0.1 1.4e-12 48.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) Aldo_ket_red PF00248.16 KUM58421.1 - 7.7e-69 231.6 0.0 9e-69 231.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.27 KUM58423.1 - 1.6e-06 27.7 9.4 0.00013 21.7 0.1 5.7 5 1 0 5 5 5 2 WD domain, G-beta repeat Kelch_6 PF13964.1 KUM58423.1 - 0.52 10.5 2.4 4.2 7.6 0.1 3.5 3 0 0 3 3 3 0 Kelch motif RNA_pol_N PF01194.12 KUM58424.1 - 5.4e-30 103.2 1.7 6.4e-30 102.9 1.2 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Clr5 PF14420.1 KUM58425.1 - 1.9e-18 66.1 1.2 1.9e-18 66.1 0.8 2.0 2 0 0 2 2 2 1 Clr5 domain Pox_G5 PF04599.7 KUM58425.1 - 0.041 12.5 0.1 0.25 10.0 0.0 2.0 1 1 1 2 2 2 0 Poxvirus G5 protein Het-C PF07217.6 KUM58426.1 - 1.3e-270 898.8 0.0 1.9e-270 898.3 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C ADH_N PF08240.7 KUM58428.1 - 4.5e-35 119.7 0.9 6.1e-35 119.2 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM58428.1 - 2.6e-20 72.2 0.2 5e-20 71.3 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 KUM58428.1 - 0.0015 17.9 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_18 PF12847.2 KUM58428.1 - 0.0027 18.2 0.0 0.0055 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KUM58428.1 - 0.0043 17.9 0.1 0.0073 17.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KUM58428.1 - 0.038 13.1 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.15 KUM58428.1 - 0.36 10.7 2.4 0.36 10.7 0.1 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus FAD-oxidase_C PF02913.14 KUM58429.1 - 7.3e-52 176.1 0.5 4.9e-51 173.4 0.2 2.0 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KUM58429.1 - 3.4e-37 127.0 0.0 7.9e-37 125.8 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Ras PF00071.17 KUM58431.1 - 8.3e-40 135.8 0.0 1.2e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KUM58431.1 - 2.6e-13 50.5 0.0 4.5e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KUM58431.1 - 7.6e-11 41.5 0.0 9.2e-10 38.0 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KUM58431.1 - 0.00036 19.7 0.0 0.00047 19.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_33 PF13671.1 KUM58431.1 - 0.012 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KUM58431.1 - 0.014 15.5 0.0 0.036 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KUM58431.1 - 0.021 14.8 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.5 KUM58431.1 - 0.034 13.3 0.0 0.053 12.7 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KUM58431.1 - 0.067 12.6 0.0 2.2 7.7 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 KUM58431.1 - 0.093 12.6 0.0 0.18 11.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KUM58431.1 - 0.099 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 KUM58431.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain UCH PF00443.24 KUM58432.1 - 3.7e-47 160.6 0.0 5.7e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KUM58432.1 - 2.9e-25 88.1 11.7 1.4e-18 66.7 1.7 3.6 2 1 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 KUM58432.1 - 2.7e-18 66.4 0.0 1.5e-17 64.0 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 KUM58432.1 - 4.3e-17 61.4 0.4 1.2e-09 37.6 0.0 2.8 2 0 0 2 2 2 2 UBA/TS-N domain DUF1815 PF08844.5 KUM58432.1 - 0.078 12.6 0.4 1.5 8.5 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1815) XK-related PF09815.4 KUM58433.1 - 0.01 14.8 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 XK-related protein Fer4_13 PF13370.1 KUM58433.1 - 0.15 12.4 5.5 4.4 7.7 0.0 4.2 3 2 1 4 4 4 0 4Fe-4S single cluster domain Fn_bind PF02986.9 KUM58433.1 - 2.9 7.4 5.0 12 5.4 0.3 2.5 2 0 0 2 2 2 0 Fibronectin binding repeat Rft-1 PF04506.8 KUM58434.1 - 7.1e-100 334.9 18.8 8.6e-100 334.6 13.0 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.12 KUM58434.1 - 2.9e-07 30.0 14.2 2.9e-07 30.0 9.9 2.7 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein DEAD PF00270.24 KUM58435.1 - 5.8e-46 156.0 0.0 3.2e-45 153.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM58435.1 - 1.5e-26 92.0 0.1 7.8e-26 89.7 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KUM58435.1 - 2.4e-06 27.5 0.0 4.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 KUM58435.1 - 0.00051 19.1 0.5 0.022 13.8 0.0 2.6 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 KUM58435.1 - 0.0058 15.0 0.0 0.16 10.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) RDD PF06271.7 KUM58436.1 - 0.1 12.5 4.2 0.11 12.3 2.9 1.2 1 0 0 1 1 1 0 RDD family DUF2393 PF09624.5 KUM58436.1 - 0.24 10.9 2.0 0.31 10.5 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) DUF4131 PF13567.1 KUM58436.1 - 2.6 7.4 5.9 2.5 7.4 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Rep_fac-A_C PF08646.5 KUM58437.1 - 9.3e-53 177.8 4.9 2.1e-50 170.2 0.4 2.3 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 KUM58437.1 - 3.8e-22 77.9 0.4 7.9e-22 76.9 0.1 1.7 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 KUM58437.1 - 4.8e-13 48.7 0.1 2.1e-08 33.8 0.0 3.5 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain Thioredoxin PF00085.15 KUM58438.1 - 0.098 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DUF3868 PF12984.2 KUM58439.1 - 0.07 12.6 0.7 3.4 7.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3868) Filament PF00038.16 KUM58439.1 - 0.12 11.8 36.0 3.4 7.0 9.6 3.1 1 1 0 1 1 1 0 Intermediate filament protein Reo_sigmaC PF04582.7 KUM58439.1 - 1.7 7.7 11.9 1.2 8.2 7.0 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein APG6 PF04111.7 KUM58439.1 - 2.2 7.2 36.4 0.58 9.1 14.6 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 ADIP PF11559.3 KUM58439.1 - 5.6 6.8 46.0 3.2 7.6 9.3 5.0 1 1 3 5 5 5 0 Afadin- and alpha -actinin-Binding DUF3678 PF12435.3 KUM58440.1 - 0.0038 16.7 4.6 0.0094 15.4 3.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3678) Sugar_tr PF00083.19 KUM58441.1 - 6.9e-100 334.7 21.8 8.1e-100 334.5 15.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM58441.1 - 2.2e-21 76.0 30.8 1.1e-14 53.9 7.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OST3_OST6 PF04756.8 KUM58442.1 - 1.3e-22 80.0 4.3 1.5e-22 79.8 3.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family VIT1 PF01988.14 KUM58442.1 - 0.03 13.8 8.9 0.6 9.5 1.2 2.1 1 1 1 2 2 2 0 VIT family DUF805 PF05656.9 KUM58442.1 - 0.059 13.1 2.8 0.1 12.4 1.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DUF2649 PF10854.3 KUM58442.1 - 0.17 12.0 1.2 0.23 11.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2649) TraX PF05857.6 KUM58442.1 - 1.5 8.4 6.1 2.9 7.4 0.6 2.0 2 0 0 2 2 2 0 TraX protein DUF4149 PF13664.1 KUM58442.1 - 2.8 8.0 6.7 9.8 6.3 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) DUF3616 PF12275.3 KUM58443.1 - 0.019 13.9 0.3 0.021 13.8 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3616) UPF0542 PF15086.1 KUM58443.1 - 1.5 8.6 7.8 0.31 10.7 1.7 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Slu7 PF11708.3 KUM58443.1 - 1.8 8.2 8.9 2 8.0 6.1 1.0 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor Membr_traf_MHD PF10540.4 KUM58444.1 - 2.7e-30 104.9 2.5 2.7e-30 104.9 0.0 2.4 3 0 0 3 3 3 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 KUM58444.1 - 3.8e-14 52.2 0.2 9.5e-14 51.0 0.0 1.9 2 0 0 2 2 2 1 C2 domain NDUF_B8 PF05821.6 KUM58445.1 - 1.8e-07 30.9 0.0 2.3e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.18 KUM58446.1 - 7.1e-72 241.7 0.3 1.1e-71 241.1 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KUM58446.1 - 1.6e-14 53.5 0.0 3.9e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KUM58446.1 - 1e-08 35.2 0.1 3e-08 33.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KUM58446.1 - 9.9e-06 25.1 0.0 2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HSA PF07529.8 KUM58446.1 - 0.00037 20.2 6.8 0.00037 20.2 4.7 2.4 2 0 0 2 2 2 1 HSA DEAD_2 PF06733.10 KUM58446.1 - 0.0045 16.4 0.2 0.018 14.4 0.0 2.0 2 0 0 2 2 2 1 DEAD_2 Glyco_hydro_47 PF01532.15 KUM58448.1 - 1.9e-130 435.5 0.0 2.3e-130 435.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AIG2_2 PF13772.1 KUM58449.1 - 0.0006 19.8 0.0 0.015 15.3 0.0 2.4 2 0 0 2 2 2 1 AIG2-like family AIG2 PF06094.7 KUM58449.1 - 0.00088 19.7 0.0 0.0014 19.0 0.0 1.5 1 1 0 1 1 1 1 AIG2-like family Pribosyltran PF00156.22 KUM58450.1 - 1.3e-17 63.6 0.0 1.7e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain AP_endonuc_2 PF01261.19 KUM58451.1 - 4e-22 78.5 0.0 5.9e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel RNase_P_p30 PF01876.11 KUM58451.1 - 0.031 13.4 0.0 0.079 12.1 0.0 1.6 2 0 0 2 2 2 0 RNase P subunit p30 Rab3-GTPase_cat PF13890.1 KUM58451.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit WD40 PF00400.27 KUM58452.1 - 1.8e-56 186.1 7.6 4.4e-09 35.8 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KUM58452.1 - 0.00027 19.8 1.1 0.091 11.4 0.2 3.2 1 1 2 3 3 3 2 Nup133 N terminal like Ribonuc_L-PSP PF01042.16 KUM58454.1 - 4e-40 136.3 0.2 4.4e-40 136.1 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP TRAPP PF04051.11 KUM58456.1 - 1.5e-32 112.2 0.0 1.7e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF4250 PF14056.1 KUM58456.1 - 0.064 12.9 0.1 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) Sec63 PF02889.11 KUM58457.1 - 9.4e-57 192.5 0.1 1.4e-56 192.0 0.1 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 KUM58457.1 - 2.2e-27 95.6 0.1 3.9e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KUM58457.1 - 3e-10 40.2 0.0 6.9e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KUM58457.1 - 1.3e-09 37.8 0.0 3.1e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KUM58457.1 - 0.00052 20.1 0.0 0.0017 18.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain SNF2_N PF00176.18 KUM58457.1 - 0.00058 18.7 0.1 0.0016 17.3 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain UvrD-helicase PF00580.16 KUM58457.1 - 0.012 14.9 0.0 0.03 13.6 0.0 1.7 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_19 PF13245.1 KUM58457.1 - 0.018 14.8 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain T2SE PF00437.15 KUM58457.1 - 0.048 12.5 0.0 0.091 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.2 KUM58457.1 - 0.1 12.0 0.1 2.4 7.5 0.0 2.3 1 1 0 2 2 2 0 AAA-like domain AAA_30 PF13604.1 KUM58457.1 - 0.16 11.5 0.0 0.37 10.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain Acid_PPase PF12689.2 KUM58458.1 - 9.7e-69 230.3 0.0 1.1e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Hexapep PF00132.19 KUM58459.1 - 1.6e-09 36.7 11.1 7.4e-05 22.0 0.2 4.5 2 2 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KUM58459.1 - 0.013 15.0 3.8 0.68 9.5 0.4 2.9 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase TPR_MLP1_2 PF07926.7 KUM58460.1 - 3.5e-30 104.4 24.7 3.5e-30 104.4 17.1 15.8 7 4 8 15 15 15 5 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 KUM58460.1 - 1.9e-05 24.5 18.9 1.9e-05 24.5 13.1 16.2 7 3 11 18 18 18 7 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WEMBL PF05701.6 KUM58460.1 - 3.1e-05 22.6 10.6 3.1e-05 22.6 7.3 9.7 5 3 4 9 9 9 2 Weak chloroplast movement under blue light TMF_DNA_bd PF12329.3 KUM58460.1 - 0.0018 18.0 10.2 0.0018 18.0 7.1 21.9 14 5 11 25 25 25 7 TATA element modulatory factor 1 DNA binding Nuc_sug_transp PF04142.10 KUM58462.1 - 1.7e-70 236.9 1.7 2.4e-70 236.4 1.2 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 KUM58462.1 - 3.2e-10 39.4 0.7 7.5e-10 38.2 0.4 1.5 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 KUM58462.1 - 3.1e-07 30.5 16.2 5.3e-06 26.6 2.9 2.6 2 1 0 2 2 2 2 Multidrug resistance efflux transporter EamA PF00892.15 KUM58462.1 - 0.013 15.5 8.2 0.013 15.5 5.7 2.6 2 1 0 2 2 2 0 EamA-like transporter family UPF0546 PF10639.4 KUM58462.1 - 0.015 15.1 0.7 0.015 15.1 0.5 2.0 2 1 0 2 2 2 0 Uncharacterised protein family UPF0546 TPT PF03151.11 KUM58462.1 - 2.4 7.7 17.1 1.1 8.8 3.6 2.9 2 1 0 2 2 2 0 Triose-phosphate Transporter family Pkinase PF00069.20 KUM58463.1 - 1.2e-60 204.8 0.0 1.6e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM58463.1 - 7.4e-24 84.2 0.0 1e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM58463.1 - 3.4e-07 29.4 0.0 4.6e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KUM58463.1 - 0.00058 19.6 0.1 0.67 9.6 0.0 2.5 3 0 0 3 3 3 2 Phosphotransferase enzyme family F-box-like PF12937.2 KUM58464.1 - 0.0002 21.0 0.0 0.00038 20.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KUM58464.1 - 0.0013 18.3 0.0 0.0024 17.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain TFIIE_beta PF02186.10 KUM58465.1 - 5.3e-06 26.3 0.3 2.6e-05 24.1 0.0 2.4 2 1 0 2 2 2 1 TFIIE beta subunit core domain DHBP_synthase PF00926.14 KUM58466.1 - 7.7e-72 240.5 0.1 5.7e-71 237.7 0.0 1.9 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase AA_permease_2 PF13520.1 KUM58467.1 - 1.1e-62 212.0 45.8 1.3e-62 211.7 31.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM58467.1 - 8.4e-25 87.0 37.1 1.2e-24 86.5 25.7 1.1 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.16 KUM58467.1 - 0.0069 16.1 0.0 0.0069 16.1 0.0 3.6 3 0 0 3 3 3 1 Gram positive anchor Rad10 PF03834.9 KUM58468.1 - 0.098 12.3 0.1 0.23 11.1 0.1 1.6 2 0 0 2 2 2 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Endothelin PF00322.12 KUM58468.1 - 1.2 8.4 3.0 0.48 9.7 0.2 1.6 2 0 0 2 2 2 0 Endothelin family Transferase PF02458.10 KUM58469.1 - 4.3e-23 81.4 0.0 5.1e-22 77.9 0.0 2.0 2 0 0 2 2 2 2 Transferase family YwiC PF14256.1 KUM58470.1 - 8 6.5 11.0 0.46 10.5 1.7 2.5 2 1 0 2 2 2 0 YwiC-like protein NuA4 PF09340.5 KUM58471.1 - 4.7e-28 96.6 0.2 4.7e-28 96.6 0.2 1.7 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Tmemb_cc2 PF10267.4 KUM58471.1 - 0.27 9.7 0.0 0.27 9.7 0.0 1.9 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Myosin_HC-like PF07058.6 KUM58471.1 - 0.38 9.8 5.6 0.52 9.3 3.9 1.1 1 0 0 1 1 1 0 Myosin II heavy chain-like Glyco_hydro_38 PF01074.17 KUM58472.1 - 2.3e-91 305.8 1.8 2.3e-91 305.8 1.3 2.7 3 0 0 3 3 3 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 KUM58472.1 - 5.3e-74 249.6 0.0 9.5e-74 248.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 KUM58472.1 - 3.4e-26 91.2 0.0 6.8e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Ctr PF04145.10 KUM58473.1 - 1.3e-33 116.1 2.2 1.9e-33 115.5 1.5 1.3 1 1 0 1 1 1 1 Ctr copper transporter family CbiQ PF02361.11 KUM58473.1 - 0.034 13.7 1.3 0.04 13.4 0.9 1.1 1 0 0 1 1 1 0 Cobalt transport protein Abi PF02517.11 KUM58473.1 - 0.09 12.9 3.5 4.8 7.3 0.1 2.2 2 0 0 2 2 2 0 CAAX protease self-immunity N_methyl_3 PF13633.1 KUM58473.1 - 3.6 7.6 7.0 8.7 6.5 0.6 2.8 2 0 0 2 2 2 0 Prokaryotic N-terminal methylation site MBOAT_2 PF13813.1 KUM58474.1 - 8.8e-23 80.1 1.6 1.8e-22 79.2 1.1 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Na_Pi_cotrans PF02690.10 KUM58474.1 - 0.081 12.6 0.3 0.081 12.6 0.2 2.0 2 1 0 2 2 2 0 Na+/Pi-cotransporter DUF457 PF04307.9 KUM58474.1 - 0.13 11.5 1.9 0.21 10.9 1.3 1.5 1 1 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) DUF106 PF01956.11 KUM58474.1 - 4.1 6.9 6.1 1.1 8.7 0.3 2.3 2 1 1 3 3 3 0 Integral membrane protein DUF106 Amino_oxidase PF01593.19 KUM58475.1 - 4.9e-29 101.6 0.1 8.2e-29 100.9 0.1 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KUM58475.1 - 1.6e-10 40.8 0.0 6.2e-10 38.9 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KUM58475.1 - 0.019 14.0 0.1 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 KUM58475.1 - 0.024 14.7 0.0 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 KUM58477.1 - 2.1e-24 85.9 17.3 3.1e-24 85.3 12.0 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM58477.1 - 3.1e-06 25.6 3.8 3.8e-06 25.4 2.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KUM58477.1 - 9.8e-06 24.3 13.4 3e-05 22.7 9.3 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 KUM58477.1 - 0.00052 18.5 8.3 0.069 11.5 0.2 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein PTR2 PF00854.16 KUM58477.1 - 0.013 14.2 0.3 0.029 13.1 0.2 1.5 1 0 0 1 1 1 0 POT family FAA_hydrolase PF01557.13 KUM58480.1 - 4.1e-48 163.7 0.0 9.9e-30 103.6 0.0 2.0 2 0 0 2 2 2 2 Fumarylacetoacetate (FAA) hydrolase family DEAD PF00270.24 KUM58481.1 - 2.6e-42 144.2 1.0 5e-42 143.2 0.7 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM58481.1 - 1.2e-27 95.6 0.5 4.1e-27 93.8 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KUM58481.1 - 0.0028 17.5 0.0 0.0053 16.6 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KUM58481.1 - 0.0032 17.0 0.1 0.0085 15.6 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KUM58481.1 - 0.0034 17.5 0.1 0.013 15.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KUM58481.1 - 0.0059 16.3 0.0 0.017 14.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain SNF2_N PF00176.18 KUM58481.1 - 0.037 12.8 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain CMS1 PF14617.1 KUM58481.1 - 0.081 11.9 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Fanconi_A PF03511.9 KUM58481.1 - 0.083 12.6 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 Fanconi anaemia group A protein Cupin_8 PF13621.1 KUM58482.1 - 3.3e-15 56.2 0.0 5.9e-14 52.1 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 KUM58482.1 - 2.6e-10 40.5 0.1 2.4e-09 37.4 0.0 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.2 KUM58482.1 - 2.1e-07 30.5 0.0 4.3e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KUM58482.1 - 0.0061 16.1 0.0 0.018 14.7 0.0 1.9 1 0 0 1 1 1 1 F-box domain SLT PF01464.15 KUM58483.1 - 3.2e-05 23.4 0.3 0.0001 21.7 0.2 1.9 1 1 0 1 1 1 1 Transglycosylase SLT domain LysM PF01476.15 KUM58483.1 - 0.00037 20.3 0.0 0.0011 18.7 0.0 1.9 2 0 0 2 2 2 1 LysM domain DUF4425 PF14466.1 KUM58483.1 - 0.03 14.4 0.6 0.066 13.3 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4425) Lysozyme_like PF13702.1 KUM58483.1 - 0.037 13.5 0.3 0.087 12.3 0.2 1.6 1 0 0 1 1 1 0 Lysozyme-like F-box-like PF12937.2 KUM58484.1 - 0.00017 21.1 0.8 0.00043 19.9 0.6 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KUM58484.1 - 0.00047 19.7 1.4 0.00065 19.2 0.2 1.8 2 0 0 2 2 2 1 F-box domain PRP8_domainIV PF12134.3 KUM58484.1 - 0.074 12.3 0.2 0.13 11.6 0.2 1.3 1 0 0 1 1 1 0 PRP8 domain IV core Pyr_redox_2 PF07992.9 KUM58485.1 - 2e-26 93.1 0.0 1e-15 58.1 0.0 3.4 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KUM58485.1 - 1.2e-11 44.8 0.0 4.3e-10 39.8 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KUM58485.1 - 0.0016 18.5 0.1 2.7 8.0 0.1 3.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase SRI PF08236.6 KUM58485.1 - 0.052 13.4 0.2 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain Arrestin_C PF02752.17 KUM58486.1 - 2.2e-17 63.4 1.8 7.1e-17 61.7 0.0 2.6 2 2 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KUM58486.1 - 6.1e-07 29.3 0.0 0.00048 19.9 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 KUM58486.1 - 0.01 15.3 0.0 0.046 13.2 0.0 2.0 2 0 0 2 2 2 0 Arrestin_N terminal like Dynamin_N PF00350.18 KUM58487.1 - 4e-45 153.6 0.0 7.3e-45 152.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KUM58487.1 - 6e-12 44.9 0.0 1.2e-08 34.1 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 KUM58487.1 - 0.00093 19.1 0.0 0.0037 17.2 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KUM58487.1 - 0.0022 18.4 0.0 0.0045 17.4 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein AAA_21 PF13304.1 KUM58487.1 - 0.16 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain GATase_4 PF13230.1 KUM58488.1 - 6.8e-14 51.1 0.0 1.3e-12 46.9 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 KUM58488.1 - 8.1e-09 35.5 0.0 1.3e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 KUM58488.1 - 5.5e-06 25.3 0.0 0.00082 18.1 0.0 2.4 3 0 0 3 3 3 2 Glutamine amidotransferases class-II DUF1021 PF06257.6 KUM58489.1 - 0.17 11.6 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1021) BORG_CEP PF14957.1 KUM58491.1 - 0.19 12.6 2.6 0.27 12.1 1.8 1.2 1 0 0 1 1 1 0 Cdc42 effector Acetyltransf_1 PF00583.19 KUM58492.1 - 2.8e-09 36.8 0.0 4.2e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KUM58492.1 - 3.2e-07 30.4 0.0 5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KUM58492.1 - 3.5e-07 30.2 0.0 5.3e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KUM58492.1 - 2.7e-05 24.0 0.1 0.0038 17.0 0.0 2.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KUM58492.1 - 0.0012 18.5 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 KUM58492.1 - 0.0022 17.8 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 KUM58492.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Abhydrolase_5 PF12695.2 KUM58493.1 - 3.2e-07 30.2 0.0 5.5e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KUM58493.1 - 2.7e-06 26.8 0.0 4.5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KUM58493.1 - 1.4e-05 24.7 0.1 3e-05 23.7 0.1 1.6 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KUM58493.1 - 4.5e-05 23.4 2.9 7.9e-05 22.6 2.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 KUM58493.1 - 0.0045 16.0 0.1 0.0088 15.0 0.0 1.5 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.7 KUM58493.1 - 0.0089 15.3 0.1 0.077 12.3 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_3 PF07859.8 KUM58493.1 - 0.03 13.9 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 KUM58493.1 - 0.056 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.15 KUM58493.1 - 0.06 13.5 0.0 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_1 PF00561.15 KUM58493.1 - 0.081 12.4 0.1 0.34 10.4 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF3089 PF11288.3 KUM58493.1 - 0.085 12.0 0.0 7.9 5.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) Chs3p PF12271.3 KUM58494.1 - 2.4e-138 460.0 14.2 2.7e-138 459.9 9.9 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF3382 PF11862.3 KUM58494.1 - 0.0065 16.3 1.3 0.029 14.2 0.9 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3382) DUF3147 PF11345.3 KUM58494.1 - 8.8 6.3 11.6 0.51 10.3 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3147) Ank_2 PF12796.2 KUM58495.1 - 2.3e-82 271.4 32.1 7.2e-17 61.5 0.0 10.1 1 1 9 11 11 11 11 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KUM58495.1 - 1.9e-43 142.1 9.0 0.0062 16.6 0.0 17.1 18 0 0 18 18 18 10 Ankyrin repeat Ank PF00023.25 KUM58495.1 - 1.5e-41 138.2 42.3 0.0009 18.9 0.1 18.3 20 0 0 20 20 20 12 Ankyrin repeat Ank_4 PF13637.1 KUM58495.1 - 4.3e-40 135.3 13.2 2.7e-06 27.7 0.0 12.3 7 4 8 15 15 15 12 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM58495.1 - 2.7e-32 110.0 21.6 0.00026 21.1 0.1 14.5 11 3 4 15 15 15 9 Ankyrin repeats (many copies) Isochorismatase PF00857.15 KUM58496.1 - 4.4e-19 69.0 0.2 8.1e-19 68.2 0.1 1.4 1 1 0 1 1 1 1 Isochorismatase family Fungal_trans PF04082.13 KUM58497.1 - 6.7e-25 87.4 0.0 1.3e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM58497.1 - 1.4e-05 24.9 14.8 3e-05 23.8 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prefoldin_2 PF01920.15 KUM58499.1 - 6.2e-24 83.8 4.3 8.1e-24 83.4 3.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF2164 PF09932.4 KUM58499.1 - 0.046 13.5 0.0 0.18 11.6 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2164) FliD_C PF07195.7 KUM58499.1 - 0.047 12.9 2.1 0.42 9.8 0.0 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Prefoldin PF02996.12 KUM58499.1 - 0.068 12.8 2.8 0.77 9.4 0.1 2.2 1 1 1 2 2 2 0 Prefoldin subunit AAA_23 PF13476.1 KUM58499.1 - 0.098 12.9 4.0 0.12 12.6 2.8 1.1 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.5 KUM58499.1 - 0.51 10.4 8.1 8.3 6.5 0.1 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DivIC PF04977.10 KUM58499.1 - 0.52 9.8 10.2 3.4 7.2 4.2 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF4164 PF13747.1 KUM58499.1 - 3.9 7.6 11.0 11 6.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) ATG27 PF09451.5 KUM58500.1 - 1e-80 270.8 0.0 1.2e-80 270.5 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 KUM58500.1 - 2.5e-05 24.0 0.0 0.015 15.0 0.0 2.6 3 0 0 3 3 3 2 Cation-independent mannose-6-phosphate receptor repeat PD40 PF07676.7 KUM58501.1 - 1e-46 155.9 26.8 1.7e-08 33.9 0.7 10.0 10 0 0 10 10 10 9 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 KUM58501.1 - 7.3e-11 41.2 6.6 0.005 15.4 0.8 6.6 4 2 2 6 6 6 5 Dipeptidyl peptidase IV (DPP IV) N-terminal region N2227 PF07942.7 KUM58502.1 - 2.5e-91 305.4 0.0 3.1e-91 305.1 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 KUM58502.1 - 1.5e-05 24.8 0.0 5e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM58502.1 - 0.0012 19.2 0.0 0.013 15.9 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM58502.1 - 0.0019 18.6 0.0 0.0046 17.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF2250 PF10007.4 KUM58503.1 - 3.2 7.7 5.4 3.1 7.7 3.8 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) BLVR PF06375.6 KUM58503.1 - 8.1 6.2 8.2 7.8 6.3 5.7 1.0 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) HSP70 PF00012.15 KUM58505.1 - 7.9e-11 40.5 0.4 2.4e-09 35.6 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 KUM58505.1 - 0.014 15.0 0.1 0.031 13.9 0.1 1.5 1 0 0 1 1 1 0 SAP30 zinc-finger MreB_Mbl PF06723.8 KUM58505.1 - 0.032 12.8 0.2 0.24 9.9 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein Chromate_transp PF02417.10 KUM58506.1 - 1.4e-32 112.6 30.9 4.5e-29 101.1 9.1 2.3 2 0 0 2 2 2 2 Chromate transporter DAD PF02109.11 KUM58506.1 - 0.11 12.5 1.0 1.2 9.1 0.1 2.5 2 0 0 2 2 2 0 DAD family AAA_2 PF07724.9 KUM58507.1 - 1.9e-46 158.0 0.0 4.2e-45 153.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KUM58507.1 - 1.6e-27 96.2 0.0 6.1e-15 55.5 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KUM58507.1 - 3.6e-24 84.4 0.2 1e-23 82.9 0.1 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 KUM58507.1 - 2.3e-15 56.5 0.0 1.8e-09 37.4 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KUM58507.1 - 3.7e-15 56.3 11.7 6.7e-06 26.2 0.0 6.3 3 2 1 6 6 5 2 AAA ATPase domain AAA_22 PF13401.1 KUM58507.1 - 9e-14 51.7 0.1 5e-05 23.4 0.0 4.2 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.21 KUM58507.1 - 1.6e-08 34.1 0.0 5.1e-05 22.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.1 KUM58507.1 - 1.6e-08 35.3 2.5 0.011 16.5 0.0 3.6 2 2 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KUM58507.1 - 1.1e-07 31.4 0.0 0.024 14.0 0.0 3.0 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_18 PF13238.1 KUM58507.1 - 1.3e-07 31.9 0.3 0.009 16.3 0.0 3.5 4 0 0 4 4 2 2 AAA domain Arch_ATPase PF01637.13 KUM58507.1 - 2e-07 30.9 0.9 0.01 15.5 0.1 4.8 4 1 1 5 5 5 1 Archaeal ATPase AAA_19 PF13245.1 KUM58507.1 - 3.3e-07 29.9 0.0 0.018 14.7 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain AAA_14 PF13173.1 KUM58507.1 - 4.9e-07 29.6 0.0 0.042 13.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 KUM58507.1 - 1.4e-05 24.3 0.0 0.14 11.2 0.0 3.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KUM58507.1 - 1.5e-05 25.0 0.1 0.3 11.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.17 KUM58507.1 - 5.9e-05 23.2 0.0 0.47 10.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase T2SE PF00437.15 KUM58507.1 - 7.3e-05 21.7 0.4 0.0033 16.3 0.1 2.6 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_33 PF13671.1 KUM58507.1 - 8.3e-05 22.4 0.0 0.19 11.6 0.0 3.1 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 KUM58507.1 - 0.00017 21.3 0.0 0.88 9.2 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KUM58507.1 - 0.00026 21.3 1.0 0.77 10.0 0.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_3 PF07726.6 KUM58507.1 - 0.00029 20.4 0.0 1.1 8.9 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 KUM58507.1 - 0.00038 19.9 0.0 0.28 10.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KUM58507.1 - 0.00048 19.5 0.0 2 7.7 0.0 3.4 2 1 1 3 3 3 2 AAA domain AAA_10 PF12846.2 KUM58507.1 - 0.00056 19.4 2.6 0.32 10.4 0.0 4.6 4 2 0 5 5 5 1 AAA-like domain DUF258 PF03193.11 KUM58507.1 - 0.00095 18.3 0.0 0.41 9.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 KUM58507.1 - 0.003 17.1 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 KUM58507.1 - 0.0032 17.2 0.0 0.21 11.3 0.0 3.2 3 0 0 3 3 3 1 NTPase NACHT PF05729.7 KUM58507.1 - 0.0052 16.4 0.0 0.44 10.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain ResIII PF04851.10 KUM58507.1 - 0.0061 16.4 0.0 2.1 8.1 0.0 3.4 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Clp_N PF02861.15 KUM58507.1 - 0.012 15.5 0.1 3.1 7.8 0.0 3.4 3 0 0 3 3 2 0 Clp amino terminal domain SRP54 PF00448.17 KUM58507.1 - 0.016 14.6 0.1 6.4 6.1 0.0 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_21 PF13304.1 KUM58507.1 - 0.017 15.0 0.0 2.3 8.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KUM58507.1 - 0.045 13.3 0.0 12 5.5 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Torsin PF06309.6 KUM58507.1 - 0.061 13.2 0.0 0.3 10.9 0.0 2.0 2 0 0 2 2 2 0 Torsin MMR_HSR1 PF01926.18 KUM58507.1 - 0.064 13.2 0.0 1.2 9.1 0.0 3.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_23 PF13476.1 KUM58507.1 - 1.3 9.3 0.0 1.3 9.3 0.0 4.0 3 2 0 3 3 2 0 AAA domain Viral_P18 PF04521.8 KUM58507.1 - 4.7 6.6 7.4 11 5.4 0.9 2.5 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF676 PF05057.9 KUM58510.1 - 6.5e-48 162.9 0.0 9.8e-48 162.3 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KUM58510.1 - 2.6e-06 27.5 0.0 4.6e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KUM58510.1 - 4.8e-06 26.2 0.0 8.8e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KUM58510.1 - 1.5e-05 24.7 0.0 2.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KUM58510.1 - 8e-05 22.3 0.0 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF2235 PF09994.4 KUM58510.1 - 0.0014 18.0 0.0 0.11 11.9 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Lipase_2 PF01674.13 KUM58510.1 - 0.018 14.3 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) Abhydrolase_2 PF02230.11 KUM58510.1 - 0.044 13.2 0.1 0.98 8.8 0.0 2.2 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase LCAT PF02450.10 KUM58510.1 - 0.14 11.1 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase tRNA-synt_2c PF01411.14 KUM58511.1 - 3.7e-10 38.7 0.0 4.8e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KUM58511.1 - 2.4e-08 33.7 0.9 4.7e-08 32.7 0.7 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Ribosomal_L22e PF01776.12 KUM58512.1 - 1.9e-50 169.5 0.4 2.3e-50 169.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF4551 PF15087.1 KUM58513.1 - 2.9 6.1 5.9 3.8 5.7 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CFEM PF05730.6 KUM58514.1 - 0.00016 21.4 7.7 0.00032 20.4 5.3 1.5 1 0 0 1 1 1 1 CFEM domain Hydrolase_6 PF13344.1 KUM58516.1 - 1.2e-21 76.4 0.0 2.5e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KUM58516.1 - 9.2e-11 41.2 0.0 6.8e-10 38.5 0.0 2.3 2 0 0 2 2 2 1 HAD-hyrolase-like Lipase_3 PF01764.20 KUM58516.1 - 0.015 14.8 0.1 0.044 13.4 0.1 1.8 1 1 0 1 1 1 0 Lipase (class 3) VEFS-Box PF09733.4 KUM58517.1 - 0.098 12.3 0.3 0.18 11.4 0.2 1.3 1 0 0 1 1 1 0 VEFS-Box of polycomb protein DIM1 PF02966.11 KUM58518.1 - 1.4e-70 234.9 0.3 1.6e-70 234.7 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 G-alpha PF00503.15 KUM58519.1 - 3.7e-114 381.4 0.1 4.5e-114 381.1 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KUM58519.1 - 3.6e-14 52.3 0.1 2.2e-09 36.7 0.0 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KUM58519.1 - 1.4e-06 27.6 0.1 0.0036 16.4 0.1 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 KUM58519.1 - 0.0018 18.7 0.0 0.12 12.9 0.0 2.6 2 1 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KUM58519.1 - 0.0071 16.2 0.0 1.8 8.5 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF1967 PF09269.6 KUM58519.1 - 0.011 15.4 0.2 5 6.8 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF1967) GTP_EFTU PF00009.22 KUM58519.1 - 0.031 13.6 0.1 5.2 6.4 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 KUM58519.1 - 0.032 13.7 0.1 0.067 12.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.1 KUM58519.1 - 0.24 10.3 5.2 0.034 13.1 0.8 1.5 2 0 0 2 2 2 0 AAA ATPase domain Translin PF01997.11 KUM58520.1 - 3.5e-50 170.3 0.0 4.1e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 Translin family FRQ PF09421.5 KUM58520.1 - 0.0049 14.7 0.0 0.0076 14.0 0.0 1.2 1 0 0 1 1 1 1 Frequency clock protein GMP_synt_C PF00958.17 KUM58520.1 - 0.014 15.1 0.1 0.15 11.8 0.0 2.3 2 0 0 2 2 2 0 GMP synthase C terminal domain GSHPx PF00255.14 KUM58521.1 - 4.2e-37 125.8 0.0 6.3e-37 125.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 KUM58521.1 - 0.0062 16.2 0.0 0.0093 15.6 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Ral PF11058.3 KUM58521.1 - 0.067 12.5 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Antirestriction protein Ral Redoxin PF08534.5 KUM58521.1 - 0.1 12.1 0.2 0.21 11.1 0.1 1.7 1 1 0 1 1 1 0 Redoxin Thioredoxin_2 PF13098.1 KUM58521.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain DapB_N PF01113.15 KUM58522.1 - 0.19 11.6 2.7 14 5.6 0.0 2.9 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus DSPn PF14671.1 KUM58523.1 - 3.6e-46 156.6 0.0 4.5e-42 143.3 0.0 3.2 3 0 0 3 3 3 3 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 KUM58523.1 - 1.3e-16 60.3 0.1 1.6e-15 56.8 0.0 2.4 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KUM58523.1 - 4.3e-06 26.2 0.1 1.2e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase LptE PF04390.7 KUM58523.1 - 0.12 12.0 0.3 0.24 11.1 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide-assembly DUF1713 PF08213.6 KUM58524.1 - 9.1e-13 47.5 19.9 9.1e-13 47.5 13.8 1.7 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.5 KUM58524.1 - 0.02 14.8 1.4 0.032 14.1 0.0 2.1 3 0 0 3 3 3 0 Mitochondrial protein Pet20 ATP-synt_C PF00137.16 KUM58525.1 - 1.2e-31 108.3 27.6 1.6e-17 63.1 8.0 2.0 2 0 0 2 2 2 2 ATP synthase subunit C Flavi_NS4A PF01350.12 KUM58525.1 - 0.19 11.2 4.4 0.049 13.1 0.8 1.6 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A DUF2970 PF11174.3 KUM58525.1 - 0.58 9.7 8.4 0.12 11.9 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Kinesin PF00225.18 KUM58526.1 - 6.6e-97 324.1 0.0 1.3e-96 323.2 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain DUF2205 PF10224.4 KUM58526.1 - 0.26 10.8 4.2 4.2 7.0 1.9 2.6 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) IGR PF09597.5 KUM58527.1 - 5.6e-21 74.1 0.2 8.9e-21 73.5 0.1 1.3 1 0 0 1 1 1 1 IGR protein motif Pkinase PF00069.20 KUM58529.1 - 4.2e-62 209.6 0.0 5e-62 209.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM58529.1 - 7.5e-33 113.6 0.0 1.1e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM58529.1 - 0.0052 15.7 0.0 0.0089 15.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KUM58529.1 - 0.039 13.6 0.1 0.1 12.2 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Asp-B-Hydro_N PF05279.6 KUM58530.1 - 3.7 7.3 10.7 5.6 6.7 7.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4554 PF15091.1 KUM58530.1 - 4.8 5.8 7.8 7.2 5.2 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Adaptin_N PF01602.15 KUM58531.1 - 1.4e-74 251.3 0.0 1.9e-69 234.4 0.0 2.0 2 0 0 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.1 KUM58531.1 - 4.6e-08 33.2 4.4 0.015 15.5 0.0 3.9 3 0 0 3 3 3 3 HEAT repeats HEAT PF02985.17 KUM58531.1 - 2.2e-05 24.1 2.3 0.34 11.0 0.0 5.2 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.2 KUM58531.1 - 0.0013 18.5 0.3 2 8.1 0.1 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Fcf2 PF08698.6 KUM58531.1 - 0.097 12.7 2.3 0.28 11.2 1.6 1.7 1 0 0 1 1 1 0 Fcf2 pre-rRNA processing HEAT_EZ PF13513.1 KUM58531.1 - 0.29 11.6 9.0 11 6.6 0.1 5.2 3 2 2 5 5 5 0 HEAT-like repeat TPR_11 PF13414.1 KUM58532.1 - 3.6e-11 42.5 1.0 8.8e-07 28.4 0.1 4.3 2 1 4 6 6 6 2 TPR repeat TPR_14 PF13428.1 KUM58532.1 - 1.2e-08 34.8 0.3 0.004 17.6 0.1 4.4 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KUM58532.1 - 3e-07 30.6 0.9 0.00078 19.7 0.0 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KUM58532.1 - 6.2e-07 29.1 0.1 0.062 13.5 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 KUM58532.1 - 5.6e-06 25.7 0.2 0.0002 20.8 0.0 3.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 KUM58532.1 - 1.4e-05 24.6 1.4 0.0028 17.4 0.1 4.7 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 KUM58532.1 - 0.00025 21.6 0.1 2.1 9.1 0.0 3.6 3 2 1 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KUM58532.1 - 0.0044 16.7 0.2 0.029 14.1 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat FAT PF02259.18 KUM58532.1 - 0.017 14.1 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 FAT domain TPR_12 PF13424.1 KUM58532.1 - 0.021 14.7 4.5 0.23 11.4 0.1 3.6 2 2 3 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 KUM58532.1 - 0.24 11.2 4.2 0.71 9.8 0.0 3.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Syja_N PF02383.13 KUM58533.1 - 9.1e-83 277.6 0.0 1.2e-82 277.2 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 KUM58533.1 - 6e-25 88.6 0.5 1e-24 87.8 0.3 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RAMP4 PF06624.7 KUM58534.1 - 8.7e-08 31.6 0.0 9.6e-08 31.4 0.0 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DAGAT PF03982.8 KUM58535.1 - 4.9e-90 301.2 0.0 6e-90 300.9 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.8 KUM58535.1 - 3.4 7.2 7.8 2.4 7.7 3.7 1.8 1 1 1 2 2 2 0 Rer1 family G-patch PF01585.18 KUM58536.1 - 1.5e-05 24.6 0.1 0.00022 20.9 0.1 2.4 1 1 0 1 1 1 1 G-patch domain DUF936 PF06075.7 KUM58536.1 - 0.0006 18.8 16.8 0.0006 18.8 11.6 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF936) TFIIF_alpha PF05793.7 KUM58536.1 - 0.24 9.7 34.4 0.3 9.4 23.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1510 PF07423.6 KUM58536.1 - 1.6 8.0 27.6 2.8 7.2 19.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FLO_LFY PF01698.11 KUM58536.1 - 1.7 7.4 12.9 2.4 6.9 8.9 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein MIP-T3 PF10243.4 KUM58536.1 - 2.4 6.5 33.9 3 6.2 23.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Vfa1 PF08432.5 KUM58536.1 - 2.6 8.0 27.7 5.1 7.0 19.2 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Hid1 PF12722.2 KUM58536.1 - 5.5 4.5 16.6 6.3 4.3 11.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2146 PF10220.4 KUM58536.1 - 9.3 4.0 14.4 11 3.8 10.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) PI3_PI4_kinase PF00454.22 KUM58537.1 - 5.7e-35 120.8 0.0 4.1e-34 118.0 0.0 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KUM58537.1 - 2.2e-24 85.6 0.0 5.4e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.1 KUM58537.1 - 0.14 11.1 0.0 0.29 10.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Sugar_tr PF00083.19 KUM58538.1 - 1.6e-140 468.6 27.4 1.8e-140 468.4 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM58538.1 - 4.3e-26 91.4 48.6 2.2e-20 72.7 17.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KUM58538.1 - 0.00058 18.3 29.6 0.0018 16.7 1.2 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein Pox_A14 PF05767.7 KUM58538.1 - 0.01 15.7 0.3 0.37 10.7 0.0 2.9 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Flavi_NS4A PF01350.12 KUM58538.1 - 4.1 6.9 5.5 3.3 7.2 0.2 2.6 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A p450 PF00067.17 KUM58539.1 - 7.5e-76 255.5 0.0 9.4e-76 255.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 KUM58540.1 - 1.9e-76 256.6 0.0 2.6e-76 256.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM58540.1 - 1.6e-36 125.7 0.0 2.3e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KUM58540.1 - 1.3e-13 50.8 0.0 2.8e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KUM58540.1 - 7.6e-11 41.5 0.0 4.4e-09 35.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KUM58540.1 - 5.1e-05 23.1 0.1 0.00012 21.9 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KUM58540.1 - 0.02 13.9 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KUM58540.1 - 0.058 12.7 0.0 0.2 10.9 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 KUM58540.1 - 0.14 10.9 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ABC_tran PF00005.22 KUM58541.1 - 2.2e-36 125.1 0.0 4.4e-18 65.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KUM58541.1 - 2.1e-29 102.7 29.3 4.4e-21 75.5 9.0 3.2 2 1 1 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 KUM58541.1 - 1e-11 45.3 6.5 9.4e-05 22.5 1.9 4.4 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 KUM58541.1 - 9.8e-10 38.0 0.2 0.0056 15.9 0.0 3.2 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain T2SE PF00437.15 KUM58541.1 - 4.5e-09 35.6 0.1 0.0016 17.3 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.1 KUM58541.1 - 1.1e-07 32.0 0.1 0.25 11.4 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KUM58541.1 - 2.4e-07 30.9 2.2 0.021 14.7 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KUM58541.1 - 4.9e-07 29.1 1.6 0.00046 19.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 KUM58541.1 - 8.2e-06 25.3 5.1 0.032 13.6 0.1 2.7 3 0 0 3 3 2 2 AAA domain SbcCD_C PF13558.1 KUM58541.1 - 3.6e-05 23.6 0.4 0.65 9.9 0.0 3.7 3 0 0 3 3 3 1 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 KUM58541.1 - 7.1e-05 22.3 0.5 0.015 14.7 0.1 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_17 PF13207.1 KUM58541.1 - 0.00015 22.6 0.0 0.23 12.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KUM58541.1 - 0.00017 21.1 0.4 0.031 13.7 0.0 2.7 3 0 0 3 3 3 1 AAA-like domain NACHT PF05729.7 KUM58541.1 - 0.00026 20.6 1.4 0.16 11.6 0.1 3.0 2 0 0 2 2 2 1 NACHT domain MobB PF03205.9 KUM58541.1 - 0.00059 19.5 1.1 0.11 12.2 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.4 KUM58541.1 - 0.00061 18.5 0.1 0.12 10.9 0.0 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.1 KUM58541.1 - 0.00076 19.3 0.1 1.3 8.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KUM58541.1 - 0.0019 18.1 0.1 0.37 10.7 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 KUM58541.1 - 0.0027 17.9 0.3 0.71 10.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 KUM58541.1 - 0.003 17.4 2.1 0.0073 16.1 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 DEAD PF00270.24 KUM58541.1 - 0.0032 16.9 0.1 3.2 7.2 0.0 3.1 3 0 0 3 3 3 0 DEAD/DEAH box helicase Zeta_toxin PF06414.7 KUM58541.1 - 0.0033 16.5 0.3 0.71 8.9 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin UPF0079 PF02367.12 KUM58541.1 - 0.0038 16.8 0.5 0.12 12.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 KUM58541.1 - 0.0049 16.0 0.4 0.5 9.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 KUM58541.1 - 0.0079 15.6 1.3 3.4 7.0 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 KUM58541.1 - 0.008 15.9 2.3 2.2 8.1 0.1 2.9 3 0 0 3 3 2 1 Part of AAA domain AAA_23 PF13476.1 KUM58541.1 - 0.0084 16.4 0.1 1.4 9.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 KUM58541.1 - 0.0085 14.9 0.0 0.67 8.7 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_14 PF13173.1 KUM58541.1 - 0.0093 15.8 0.0 15 5.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.16 KUM58541.1 - 0.014 14.5 0.8 1.2 8.2 0.0 2.7 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 KUM58541.1 - 0.018 14.2 0.1 3.3 6.9 0.0 3.1 3 0 0 3 3 3 0 PhoH-like protein PduV-EutP PF10662.4 KUM58541.1 - 0.02 14.3 2.9 1.5 8.3 0.2 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.20 KUM58541.1 - 0.021 14.3 0.3 7.5 5.9 0.1 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Arch_ATPase PF01637.13 KUM58541.1 - 0.022 14.4 0.0 1.5 8.4 0.0 2.9 2 1 0 2 2 2 0 Archaeal ATPase ATP_bind_1 PF03029.12 KUM58541.1 - 0.027 13.9 0.2 4.2 6.8 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.9 KUM58541.1 - 0.039 13.6 1.4 1.2 8.9 0.1 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KUM58541.1 - 0.039 13.5 0.1 2.2 7.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 KUM58541.1 - 0.047 14.1 1.3 0.92 10.0 0.1 2.7 2 0 0 2 2 2 0 Miro-like protein BioY PF02632.9 KUM58541.1 - 0.056 13.0 8.1 0.017 14.7 1.9 2.5 2 0 0 2 2 2 0 BioY family ResIII PF04851.10 KUM58541.1 - 0.072 12.9 0.0 9.5 6.0 0.0 2.7 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit AAA PF00004.24 KUM58541.1 - 0.074 13.2 0.6 6.5 6.9 0.1 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.18 KUM58541.1 - 0.079 12.3 2.0 1.7 8.0 0.0 2.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain IstB_IS21 PF01695.12 KUM58541.1 - 0.08 12.3 0.5 11 5.3 0.0 2.9 3 0 0 3 3 2 0 IstB-like ATP binding protein RNA_helicase PF00910.17 KUM58541.1 - 0.089 12.9 0.3 11 6.2 0.0 3.0 3 0 0 3 3 2 0 RNA helicase Dynamin_N PF00350.18 KUM58541.1 - 0.11 12.2 1.3 10 5.9 0.1 2.4 2 0 0 2 2 2 0 Dynamin family DUF2075 PF09848.4 KUM58541.1 - 0.23 10.4 1.8 5.6 5.8 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 KUM58541.1 - 0.37 10.2 1.2 12 5.3 0.0 2.7 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 KUM58541.1 - 0.56 9.8 2.6 7.4 6.2 0.1 2.4 2 0 0 2 2 2 0 NTPase MFS_1 PF07690.11 KUM58542.1 - 2.5e-36 125.1 36.6 2.5e-36 125.1 25.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM58542.1 - 5.9e-13 48.1 25.9 5.4e-12 45.0 17.6 2.8 1 1 1 2 2 2 1 Sugar (and other) transporter Colicin_im PF03857.8 KUM58542.1 - 0.15 11.7 3.1 5 6.8 0.4 2.5 2 0 0 2 2 2 0 Colicin immunity protein Flavin_Reduct PF01613.13 KUM58546.1 - 1.5e-17 63.9 0.0 2.2e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Fungal_trans PF04082.13 KUM58547.1 - 1.4e-20 73.3 0.0 4.3e-19 68.4 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain PAP_central PF04928.12 KUM58549.1 - 1.7e-89 298.9 0.0 2.5e-89 298.4 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 KUM58549.1 - 2.7e-49 166.7 0.0 4.3e-49 166.0 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain Nrap PF03813.9 KUM58549.1 - 0.066 10.7 0.0 0.11 9.9 0.0 1.3 1 0 0 1 1 1 0 Nrap protein PAP_central PF04928.12 KUM58550.1 - 2e-05 23.5 0.0 2.7e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain Abhydrolase_1 PF00561.15 KUM58551.1 - 5.6e-12 45.7 0.0 5e-11 42.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KUM58551.1 - 3.3e-11 43.5 0.0 4.5e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KUM58551.1 - 0.035 13.3 0.0 0.15 11.2 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KUM58551.1 - 0.07 12.8 0.0 0.46 10.2 0.0 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family Alpha-amylase PF00128.19 KUM58552.1 - 2e-21 76.6 0.1 2.9e-11 43.3 0.0 2.1 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 KUM58552.1 - 0.0021 15.9 0.1 0.45 8.2 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 70 DUF3632 PF12311.3 KUM58553.1 - 1e-47 162.3 0.4 1.3e-47 162.0 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Mito_carr PF00153.22 KUM58554.1 - 1.6e-47 159.1 9.0 1.3e-17 63.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pro_racemase PF05544.6 KUM58555.1 - 9.7e-58 195.5 0.1 2.3e-56 191.0 0.0 2.1 1 1 0 1 1 1 1 Proline racemase Sugar_tr PF00083.19 KUM58556.1 - 2.5e-95 319.7 21.8 2.8e-95 319.5 15.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM58556.1 - 1.5e-33 116.0 45.8 3.5e-27 95.0 15.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4211 PF13926.1 KUM58557.1 - 2.5e-43 147.1 0.0 2.5e-43 147.1 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) Tom22 PF04281.8 KUM58558.1 - 1.4e-53 180.1 1.5 1.6e-53 179.8 1.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 AMP-binding PF00501.23 KUM58559.1 - 8.4e-43 146.3 0.0 1.2e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KUM58559.1 - 0.00027 21.8 0.0 0.00066 20.5 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3368 PF11848.3 KUM58559.1 - 0.13 11.8 0.1 1.8 8.1 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3368) Aminotran_1_2 PF00155.16 KUM58560.1 - 1.1e-64 218.7 0.0 1.3e-64 218.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KUM58560.1 - 0.0066 15.6 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Tmemb_18A PF09771.4 KUM58560.1 - 0.097 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 188 PAT1 PF09770.4 KUM58561.1 - 0.64 8.1 57.9 0.85 7.7 40.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_M16_C PF05193.16 KUM58562.1 - 6e-49 166.2 0.0 1.7e-48 164.7 0.0 1.8 1 1 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KUM58562.1 - 3.5e-40 137.1 0.0 1e-38 132.4 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) ADH_N PF08240.7 KUM58563.1 - 3.3e-11 42.8 0.1 8.3e-11 41.6 0.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM58563.1 - 3.8e-09 36.1 0.1 7.7e-09 35.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.13 KUM58564.1 - 0.00052 18.9 0.3 0.00052 18.9 0.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KUM58566.1 - 1.6e-27 96.1 49.4 1.6e-27 96.1 34.2 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM58567.1 - 1.4e-115 386.4 31.8 1.7e-115 386.2 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM58567.1 - 7.8e-25 87.3 34.9 2.6e-22 79.0 18.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KUM58567.1 - 1e-06 27.4 30.2 0.00036 19.0 7.2 3.2 3 1 0 3 3 3 2 MFS/sugar transport protein Rhomboid PF01694.17 KUM58569.1 - 8.1e-34 116.7 7.7 8.1e-34 116.7 5.3 1.9 2 0 0 2 2 2 1 Rhomboid family DUF4203 PF13886.1 KUM58569.1 - 0.011 15.1 0.4 0.011 15.1 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4203) Asparaginase PF00710.15 KUM58570.1 - 2.1e-70 237.0 1.0 2.5e-70 236.8 0.7 1.0 1 0 0 1 1 1 1 Asparaginase NMO PF03060.10 KUM58570.1 - 0.0097 15.0 0.5 0.02 14.0 0.3 1.5 1 0 0 1 1 1 1 Nitronate monooxygenase TPP_enzyme_M PF00205.17 KUM58570.1 - 0.11 12.2 0.1 0.41 10.4 0.0 1.9 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain UQ_con PF00179.21 KUM58571.1 - 7.9e-21 73.9 0.0 1.1e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KUM58571.1 - 0.051 13.4 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 RWD domain zf-DHHC PF01529.15 KUM58572.1 - 1.7e-41 141.4 3.3 1.7e-41 141.4 2.3 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Nod_GRP PF07806.6 KUM58572.1 - 1.2 8.8 7.8 0.14 11.8 1.4 2.4 2 0 0 2 2 2 0 Nodule-specific GRP repeat PLDc_2 PF13091.1 KUM58573.1 - 4.9e-13 48.9 0.0 2.6e-05 23.9 0.0 3.5 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.17 KUM58573.1 - 1.4e-12 46.9 1.9 3.4e-05 23.5 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Kinetochor_Ybp2 PF08568.5 KUM58575.1 - 4.7e-149 497.5 0.0 5.9e-149 497.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin FA_hydroxylase PF04116.8 KUM58576.1 - 1.8e-13 50.8 11.9 1.8e-13 50.8 8.3 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DHDPS PF00701.17 KUM58577.1 - 5.1e-40 136.8 0.0 5.9e-40 136.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Fungal_trans PF04082.13 KUM58578.1 - 6.6e-29 100.5 0.1 9.3e-29 100.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain CCSMST1 PF15013.1 KUM58578.1 - 0.039 13.8 0.2 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 CCSMST1 family DUF846 PF05832.7 KUM58578.1 - 0.078 12.6 1.4 0.96 9.1 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF846) MFS_1 PF07690.11 KUM58579.1 - 1.4e-31 109.5 25.5 1.4e-31 109.5 17.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3040 PF11239.3 KUM58579.1 - 0.99 9.4 8.7 3.8 7.6 0.4 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3040) FAD_binding_3 PF01494.14 KUM58580.1 - 5.7e-26 91.3 0.0 1e-25 90.5 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KUM58580.1 - 9.5e-09 34.6 0.1 0.0025 16.8 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KUM58580.1 - 5.6e-05 22.3 0.4 0.21 10.6 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 KUM58580.1 - 0.0033 16.3 3.3 0.42 9.4 0.0 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KUM58580.1 - 0.0078 16.1 0.4 0.018 14.9 0.3 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM58580.1 - 0.014 15.4 0.3 0.033 14.1 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KUM58580.1 - 0.051 12.4 0.7 0.15 10.8 0.2 1.8 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 KUM58580.1 - 0.09 11.6 0.9 0.18 10.6 0.2 1.7 2 1 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 KUM58580.1 - 0.12 11.4 0.2 0.25 10.4 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 KUM58580.1 - 0.61 10.5 5.3 0.43 11.0 0.3 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase COesterase PF00135.23 KUM58581.1 - 4e-54 184.2 0.0 4.9e-54 183.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KUM58581.1 - 8.9e-06 25.4 0.0 0.00012 21.7 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Alpha-L-AF_C PF06964.7 KUM58582.1 - 1.9e-42 145.0 0.0 2.9e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus CBM_4_9 PF02018.12 KUM58582.1 - 0.0042 17.1 3.2 0.0067 16.4 0.5 2.4 2 0 0 2 2 2 1 Carbohydrate binding domain CTP_synth_N PF06418.9 KUM58583.1 - 5.4e-83 278.2 1.7 6.6e-83 277.9 1.2 1.0 1 0 0 1 1 1 1 CTP synthase N-terminus CbiA PF01656.18 KUM58583.1 - 0.0028 17.0 0.0 0.0036 16.7 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF3939 PF13075.1 KUM58583.1 - 0.018 14.7 0.0 0.054 13.2 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3939) DUF4561 PF15120.1 KUM58583.1 - 0.1 12.0 0.0 0.22 10.9 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4561) Ribosomal_L5_C PF00673.16 KUM58584.1 - 3.2e-23 81.2 0.0 5.3e-23 80.5 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KUM58584.1 - 9.7e-19 66.9 0.1 3.4e-18 65.1 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.17 KUM58585.1 - 1.3e-18 66.2 0.0 1.6e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain Clathrin PF00637.15 KUM58586.1 - 1.9e-198 650.0 33.8 1.9e-34 118.3 0.2 7.5 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 KUM58586.1 - 1.3e-34 116.1 0.3 5.6e-07 29.4 0.0 7.6 7 0 0 7 7 7 7 Clathrin propeller repeat Clathrin_H_link PF13838.1 KUM58586.1 - 1e-28 99.0 0.2 5.1e-28 96.7 0.2 2.4 1 0 0 1 1 1 1 Clathrin-H-link TPR_7 PF13176.1 KUM58586.1 - 0.007 16.0 5.9 46 4.1 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 KUM58586.1 - 0.018 14.9 6.1 4.5 7.2 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 KUM58586.1 - 0.084 12.8 3.7 6.1 7.0 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 KUM58586.1 - 5.1 8.0 16.4 13 6.7 0.1 7.6 9 0 0 9 9 9 0 Tetratricopeptide repeat Sugar_tr PF00083.19 KUM58587.1 - 1e-27 96.8 28.0 2.6e-27 95.5 19.4 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM58587.1 - 1.6e-20 73.1 42.9 7.1e-17 61.1 10.3 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily PIRT PF15099.1 KUM58587.1 - 0.01 15.0 2.4 0.012 14.8 0.3 2.0 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Peptidase_A8 PF01252.13 KUM58587.1 - 0.14 11.8 3.3 0.31 10.6 1.4 2.3 1 1 1 2 2 2 0 Signal peptidase (SPase) II AA_permease PF00324.16 KUM58589.1 - 4.4e-49 167.1 22.7 5.6e-49 166.7 15.7 1.1 1 0 0 1 1 1 1 Amino acid permease MPC PF03650.8 KUM58590.1 - 7.1e-33 113.0 1.2 1.1e-32 112.4 0.1 1.9 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0041) Phage_Coat_B PF05356.6 KUM58590.1 - 0.072 12.7 0.1 0.14 11.8 0.1 1.5 1 1 0 1 1 1 0 Phage Coat protein B Aa_trans PF01490.13 KUM58591.1 - 3.1e-83 279.5 31.2 4.1e-83 279.1 21.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CPSase_L_D2 PF02786.12 KUM58593.1 - 4.3e-78 261.4 0.1 6.8e-78 260.7 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 KUM58593.1 - 3.4e-62 209.3 0.0 5.8e-62 208.6 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 KUM58593.1 - 2.9e-36 123.9 0.0 5.4e-36 123.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KUM58593.1 - 2.8e-29 101.2 0.0 9.4e-29 99.5 0.0 2.0 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 KUM58593.1 - 3.3e-27 95.6 0.0 6e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.17 KUM58593.1 - 2.5e-17 62.2 4.0 2.7e-17 62.1 1.4 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 KUM58593.1 - 1.9e-16 60.3 0.1 4.9e-16 59.0 0.1 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KUM58593.1 - 3.4e-16 58.9 0.0 9.6e-16 57.4 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 KUM58593.1 - 1.5e-10 40.5 4.1 2e-06 27.3 0.1 3.4 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 KUM58593.1 - 7.6e-08 31.9 0.0 1.4e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KUM58593.1 - 2.7e-07 30.1 0.0 5.2e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KUM58593.1 - 7e-06 25.9 0.0 1.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 KUM58593.1 - 0.00013 22.2 0.1 0.04 14.2 0.1 3.5 3 1 1 4 4 3 1 HlyD family secretion protein HlyD_2 PF12700.2 KUM58593.1 - 0.00049 19.3 0.0 0.53 9.3 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein RimK PF08443.6 KUM58593.1 - 0.00059 19.3 0.0 0.0021 17.5 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD PF00529.15 KUM58593.1 - 0.00081 18.7 0.1 0.032 13.5 0.0 2.3 2 0 0 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.1 KUM58593.1 - 0.017 14.8 1.3 1.6 8.5 0.1 2.8 2 1 1 3 3 2 0 RnfC Barrel sandwich hybrid domain GARS_A PF01071.14 KUM58593.1 - 0.032 13.8 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GCV_H PF01597.14 KUM58593.1 - 0.19 11.4 1.1 1.7 8.3 0.1 2.8 2 1 1 3 3 3 0 Glycine cleavage H-protein GATase PF00117.23 KUM58594.1 - 1.1e-45 155.5 0.3 1.4e-45 155.0 0.2 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KUM58594.1 - 3.4e-10 39.7 0.3 7.9e-10 38.5 0.2 1.6 1 1 0 1 1 1 1 Peptidase C26 CTP_synth_N PF06418.9 KUM58594.1 - 0.00028 20.0 0.0 0.00047 19.3 0.0 1.3 1 0 0 1 1 1 1 CTP synthase N-terminus AdoMet_Synthase PF01941.14 KUM58594.1 - 0.031 12.7 0.1 0.045 12.2 0.1 1.2 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) GHMP_kinases_N PF00288.21 KUM58595.1 - 1.1e-17 63.8 0.0 2.9e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KUM58595.1 - 6.2e-07 29.5 0.0 6.2e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 KUM58595.1 - 0.0021 17.2 0.0 0.0044 16.2 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Hydantoinase_B PF02538.9 KUM58596.1 - 3.3e-11 42.1 0.0 3.3e-11 42.1 0.0 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Aldedh PF00171.17 KUM58597.1 - 3.2e-13 48.8 8.9 1.2e-11 43.6 4.7 2.8 2 1 0 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.6 KUM58597.1 - 0.0099 15.1 0.1 0.023 13.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) Ribosomal_L18e PF00828.14 KUM58598.1 - 7.3e-24 84.5 0.1 1.3e-23 83.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 YopD PF05844.7 KUM58598.1 - 0.0079 15.2 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 YopD protein PCI PF01399.22 KUM58599.1 - 0.037 14.3 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 PCI domain DLH PF01738.13 KUM58601.1 - 6.6e-26 90.9 0.0 1e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family MBOAT PF03062.14 KUM58601.1 - 3.4e-22 78.9 13.9 3.4e-22 78.9 9.6 3.2 2 2 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Abhydrolase_5 PF12695.2 KUM58601.1 - 3.5e-08 33.3 0.0 7.6e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family MBOAT_2 PF13813.1 KUM58601.1 - 1.6e-05 24.8 3.0 4.5e-05 23.4 2.1 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Abhydrolase_6 PF12697.2 KUM58601.1 - 0.0011 18.8 0.2 0.0098 15.7 0.0 2.3 2 1 1 3 3 3 1 Alpha/beta hydrolase family UPF0093 PF03653.8 KUM58601.1 - 1.3 8.9 12.1 0.39 10.6 5.1 2.5 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0093) Pneumo_att_G PF05539.6 KUM58602.1 - 1.6 8.0 7.2 1.6 7.9 5.0 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Peptidase_M24 PF00557.19 KUM58603.1 - 1.3e-52 178.4 0.3 1.8e-52 177.9 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KUM58603.1 - 5.7e-25 87.2 0.0 1.2e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Zn_clus PF00172.13 KUM58604.1 - 6.9e-09 35.4 7.4 6.9e-09 35.4 5.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KUM58604.1 - 5e-05 22.3 0.1 7.5e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Hydantoinase_B PF02538.9 KUM58605.1 - 1.7e-103 346.6 0.0 2.5e-103 346.1 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KUM58605.1 - 1.1e-92 310.1 0.3 1.1e-92 310.1 0.2 1.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KUM58605.1 - 1e-56 191.2 1.2 3.6e-55 186.1 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region RRM_1 PF00076.17 KUM58606.1 - 1.5e-11 43.7 0.0 2e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM58606.1 - 8.8e-08 32.0 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM58606.1 - 4.5e-07 29.6 0.0 6.2e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KUM58606.1 - 0.0033 17.1 0.0 0.0048 16.6 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF1510 PF07423.6 KUM58606.1 - 8.6 5.6 8.0 12 5.1 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NiFe_hyd_SSU_C PF14720.1 KUM58607.1 - 0.099 12.6 0.9 0.14 12.2 0.6 1.3 1 0 0 1 1 1 0 NiFe/NiFeSe hydrogenase small subunit C-terminal BTB PF00651.26 KUM58608.1 - 0.0017 18.3 0.1 0.0064 16.4 0.0 1.9 2 1 0 2 2 2 1 BTB/POZ domain Mito_carr PF00153.22 KUM58609.1 - 2.8e-75 248.0 2.5 4.4e-25 87.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PXA PF02194.10 KUM58611.1 - 1.5e-37 128.9 0.0 3.1e-37 127.9 0.0 1.5 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 KUM58611.1 - 3.8e-23 81.7 0.0 1e-22 80.3 0.0 1.8 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 KUM58611.1 - 8.2e-10 38.4 0.2 1.4e-08 34.4 0.0 2.4 2 0 0 2 2 2 1 PX domain PC4 PF02229.11 KUM58612.1 - 2.8e-20 71.2 0.1 4.4e-20 70.6 0.0 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) CH PF00307.26 KUM58613.1 - 1.6e-64 214.6 0.0 1.9e-20 72.9 0.2 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 KUM58613.1 - 3.9e-05 23.6 0.4 0.0021 18.1 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain pair CAMSAP_CH PF11971.3 KUM58613.1 - 0.00022 20.8 0.0 1 9.0 0.0 3.7 4 0 0 4 4 4 1 CAMSAP CH domain EF-hand_6 PF13405.1 KUM58613.1 - 0.046 13.6 0.4 3.6 7.7 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.27 KUM58613.1 - 0.11 11.8 0.6 14 5.2 0.1 3.3 3 0 0 3 3 3 0 EF hand DDHD PF02862.12 KUM58614.1 - 5.2e-70 235.7 2.5 4e-67 226.3 0.0 2.4 2 0 0 2 2 2 2 DDHD domain Lipase_3 PF01764.20 KUM58614.1 - 0.16 11.5 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Pyr_redox_3 PF13738.1 KUM58616.1 - 4.2e-05 23.7 0.0 0.00022 21.3 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Arf PF00025.16 KUM58617.1 - 1.9e-39 134.7 0.0 6.4e-26 90.6 0.0 2.3 2 1 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 KUM58617.1 - 1.9e-13 49.8 0.0 4.9e-07 28.7 0.0 2.3 2 1 0 2 2 2 2 G-protein alpha subunit Miro PF08477.8 KUM58617.1 - 2.3e-07 31.3 0.0 2.4e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Ras PF00071.17 KUM58617.1 - 1.2e-06 28.0 0.0 0.0011 18.4 0.0 2.7 2 1 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 KUM58617.1 - 1.6e-06 28.0 0.0 9.8e-06 25.5 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KUM58617.1 - 1.7e-06 27.3 0.0 2e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KUM58617.1 - 3.7e-06 26.4 0.0 0.00016 21.1 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KUM58617.1 - 7.6e-06 25.2 0.0 6.5e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 KUM58617.1 - 0.1 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter FeoB_N PF02421.13 KUM58617.1 - 0.11 11.7 0.0 0.23 10.7 0.0 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B Abhydrolase_6 PF12697.2 KUM58618.1 - 3.6e-05 23.7 0.0 3.9e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family FAD_binding_4 PF01565.18 KUM58619.1 - 0.00064 19.2 0.0 0.0011 18.4 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain PIGA PF08288.7 KUM58621.1 - 3.9e-46 155.3 2.4 7.9e-46 154.3 0.7 2.1 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 KUM58621.1 - 5e-29 100.9 0.0 7.8e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KUM58621.1 - 4.5e-15 56.0 0.0 7.6e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KUM58621.1 - 9.1e-11 41.7 0.4 1.9e-10 40.7 0.3 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 KUM58621.1 - 2.2e-10 40.9 0.0 4e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 KUM58621.1 - 0.0019 18.4 0.0 0.017 15.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 DEAD PF00270.24 KUM58622.1 - 6e-33 113.7 0.0 4.3e-15 55.6 0.0 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM58622.1 - 1.3e-17 63.4 0.4 4.1e-17 61.8 0.3 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KUM58622.1 - 1.3e-06 28.3 0.0 7.1e-06 25.9 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Glyco_hydro_3 PF00933.16 KUM58623.1 - 2.1e-73 246.9 0.0 4.2e-73 245.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KUM58623.1 - 4.2e-49 167.1 0.1 6.9e-49 166.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KUM58623.1 - 2e-08 34.0 0.0 6.6e-08 32.3 0.0 2.0 1 0 0 1 1 1 1 Fibronectin type III-like domain Ank_2 PF12796.2 KUM58625.1 - 9.8e-84 275.8 13.7 9.6e-19 67.5 1.9 4.8 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 KUM58625.1 - 2.5e-51 169.0 18.6 7.8e-06 25.4 0.0 10.8 10 0 0 10 10 10 10 Ankyrin repeat Ank_4 PF13637.1 KUM58625.1 - 3.8e-42 141.9 16.7 2.6e-08 34.1 0.0 8.1 3 2 7 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM58625.1 - 2.3e-40 132.5 4.8 0.0006 19.8 0.0 10.2 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.1 KUM58625.1 - 7.4e-31 105.4 17.4 2.3e-07 30.8 0.0 9.1 1 1 9 10 10 10 8 Ankyrin repeats (many copies) AAA_22 PF13401.1 KUM58625.1 - 6e-06 26.4 0.0 1.3e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KUM58625.1 - 1.6e-05 24.6 0.0 3.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain RVP PF00077.15 KUM58625.1 - 0.01 15.7 0.1 24 4.9 0.0 3.6 3 0 0 3 3 3 0 Retroviral aspartyl protease Apo-CII PF05355.6 KUM58625.1 - 0.032 14.0 0.1 0.072 12.9 0.1 1.6 1 0 0 1 1 1 0 Apolipoprotein C-II gag-asp_proteas PF13975.1 KUM58625.1 - 0.034 13.9 0.5 2.3 8.0 0.0 2.8 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease Ank_2 PF12796.2 KUM58627.1 - 1.8e-52 175.5 4.3 1.7e-15 57.0 0.1 4.5 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KUM58627.1 - 2.7e-42 142.3 11.4 8.6e-11 42.0 0.0 5.8 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 KUM58627.1 - 4.8e-37 123.9 25.7 6.7e-05 22.5 0.1 9.8 9 0 0 9 9 9 9 Ankyrin repeat SRP19 PF01922.12 KUM58627.1 - 1.6e-28 99.0 0.0 3.2e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 SRP19 protein Ank_5 PF13857.1 KUM58627.1 - 2.8e-26 90.9 24.1 3.8e-05 23.7 0.1 9.3 1 1 8 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM58627.1 - 8.3e-26 87.4 13.8 0.0082 16.2 0.0 10.2 10 0 0 10 10 10 6 Ankyrin repeat NACHT PF05729.7 KUM58627.1 - 7.6e-08 32.1 0.0 1.7e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KUM58627.1 - 0.00055 19.9 0.0 0.0062 16.5 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KUM58627.1 - 0.00069 19.7 0.0 0.0023 18.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KUM58627.1 - 0.0025 17.9 0.0 0.077 13.1 0.0 2.9 3 0 0 3 3 3 1 RNA helicase FA_hydroxylase PF04116.8 KUM58629.1 - 9.9e-18 64.6 12.5 9.9e-18 64.6 8.6 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Fungal_trans PF04082.13 KUM58630.1 - 6.2e-16 58.0 0.1 1.2e-15 57.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM58630.1 - 1.6e-11 43.9 10.6 2.8e-11 43.1 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TCTP PF00838.12 KUM58631.1 - 1.2e-37 129.4 0.1 1.5e-37 129.1 0.1 1.1 1 0 0 1 1 1 1 Translationally controlled tumour protein BamHI PF02923.10 KUM58631.1 - 0.017 15.0 0.3 0.03 14.2 0.2 1.3 1 0 0 1 1 1 0 Restriction endonuclease BamHI TSKS PF15358.1 KUM58633.1 - 0.049 11.8 0.9 0.065 11.3 0.6 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate MFS_1 PF07690.11 KUM58635.1 - 3.5e-21 75.3 40.2 3.9e-20 71.8 27.4 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KUM58635.1 - 0.0052 16.5 4.5 0.0052 16.5 3.1 2.6 2 0 0 2 2 2 1 MFS_1 like family Ras PF00071.17 KUM58636.1 - 3.6e-52 176.0 0.0 4.2e-52 175.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KUM58636.1 - 6.2e-16 58.9 0.0 9e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KUM58636.1 - 6.4e-06 25.5 0.0 8.9e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Arginase PF00491.16 KUM58637.1 - 7.3e-92 307.5 0.0 8.6e-92 307.3 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 KUM58637.1 - 0.00025 21.2 0.2 0.00056 20.1 0.1 1.5 1 0 0 1 1 1 1 UPF0489 domain DUF1301 PF06979.7 KUM58637.1 - 0.18 11.9 0.0 0.29 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1301) Ketoacyl-synt_C PF02801.17 KUM58640.1 - 5.6e-25 87.4 1.2 6.9e-25 87.1 0.8 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_C PF02803.13 KUM58640.1 - 0.12 11.8 0.2 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 Thiolase, C-terminal domain SCA7 PF08313.7 KUM58641.1 - 8.1e-33 111.8 3.3 8.1e-33 111.8 2.3 2.3 2 0 0 2 2 2 1 SCA7, zinc-binding domain CDC45 PF02724.9 KUM58641.1 - 0.47 8.4 11.0 0.65 7.9 7.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1349 PF07081.6 KUM58642.1 - 2.6e-24 85.5 0.0 3.1e-24 85.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) mRNA_cap_enzyme PF01331.14 KUM58643.1 - 3.6e-52 176.8 0.1 5e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 KUM58643.1 - 1.2e-22 80.1 0.0 2.3e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 KUM58643.1 - 2e-07 30.6 0.2 1.9e-06 27.3 0.1 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain MOZ_SAS PF01853.13 KUM58644.1 - 4.5e-85 283.6 0.1 6.5e-85 283.1 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 KUM58644.1 - 2.6e-23 81.4 0.0 5.7e-23 80.3 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 KUM58644.1 - 0.055 13.5 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF4484 PF14831.1 KUM58644.1 - 0.19 11.8 1.6 0.32 11.0 0.2 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4484) CAP59_mtransfer PF11735.3 KUM58645.1 - 3.9e-81 271.8 0.0 5e-81 271.4 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Peptidase_M14 PF00246.19 KUM58647.1 - 4.7e-74 249.4 0.0 5.9e-74 249.1 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 KUM58647.1 - 0.18 10.6 0.0 1.7 7.4 0.0 2.1 2 0 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family Sec7 PF01369.15 KUM58648.1 - 3.2e-37 128.0 0.0 5.6e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 KUM58648.1 - 6.6e-05 23.0 0.3 0.00014 22.0 0.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain p450 PF00067.17 KUM58648.1 - 0.0084 14.6 0.0 0.015 13.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 PH PF00169.24 KUM58648.1 - 0.014 15.5 0.1 0.03 14.5 0.1 1.6 1 0 0 1 1 1 0 PH domain Zip PF02535.17 KUM58649.1 - 8.3e-28 97.3 17.9 1.6e-26 93.0 12.4 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter zf-C3HC4_2 PF13923.1 KUM58650.1 - 6.4e-08 32.4 15.1 0.00023 21.0 3.2 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KUM58650.1 - 5.9e-06 26.0 12.6 0.0041 16.9 4.3 2.6 2 1 0 2 2 2 2 Ring finger domain Rtf2 PF04641.7 KUM58650.1 - 0.00018 20.8 13.7 0.00054 19.2 1.3 2.8 2 1 1 3 3 3 2 Rtf2 RING-finger Atg14 PF10186.4 KUM58650.1 - 0.00051 19.0 2.0 0.0009 18.2 1.4 1.5 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 zf-RING_5 PF14634.1 KUM58650.1 - 0.00085 19.0 8.9 0.00085 19.0 6.2 2.6 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KUM58650.1 - 0.0016 18.0 4.6 0.0016 18.0 3.2 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 KUM58650.1 - 0.0032 17.3 11.3 0.025 14.4 3.6 3.1 2 1 1 3 3 3 1 FYVE zinc finger zf-RING_UBOX PF13445.1 KUM58650.1 - 0.007 16.0 5.4 0.007 16.0 3.8 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Vps39_2 PF10367.4 KUM58650.1 - 0.019 15.1 1.0 0.019 15.1 0.7 3.3 4 0 0 4 4 3 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4_4 PF15227.1 KUM58650.1 - 1.4 8.8 11.9 0.35 10.7 1.5 3.3 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING IBR PF01485.16 KUM58650.1 - 9.3 6.2 12.0 6.4 6.7 0.5 3.4 3 1 0 3 3 3 0 IBR domain Endonuclease_NS PF01223.18 KUM58651.1 - 1.6e-59 201.0 0.0 2.2e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Sedlin_N PF04628.8 KUM58652.1 - 5.7e-41 139.4 0.0 6.6e-41 139.2 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 KUM58652.1 - 0.0009 18.9 0.0 0.005 16.5 0.0 1.9 2 0 0 2 2 2 1 Sybindin-like family Lumazine_bd PF12870.2 KUM58652.1 - 0.15 12.1 0.1 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Lumazine-binding domain Dishevelled PF02377.10 KUM58652.1 - 0.38 10.9 2.8 0.66 10.2 1.9 1.4 1 0 0 1 1 1 0 Dishevelled specific domain Ribosomal_S30 PF04758.9 KUM58653.1 - 5.9e-26 89.9 5.9 9.8e-26 89.2 4.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S30 DUF2040 PF09745.4 KUM58654.1 - 4.4e-39 133.2 18.1 4.4e-39 133.2 12.5 3.8 4 1 0 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) AAA_16 PF13191.1 KUM58655.1 - 7.2e-09 35.8 0.0 3e-08 33.8 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KUM58655.1 - 2.3e-05 24.5 0.0 0.00052 20.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 KUM58655.1 - 3.1e-05 23.6 0.0 0.00012 21.8 0.0 2.1 1 0 0 1 1 1 1 NACHT domain TPR_7 PF13176.1 KUM58655.1 - 4.1e-05 23.0 3.3 2.1 8.3 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 KUM58655.1 - 8.2e-05 22.4 18.7 1.3 9.0 1.2 8.5 7 2 0 8 8 8 1 Tetratricopeptide repeat AAA_19 PF13245.1 KUM58655.1 - 0.00041 20.0 0.0 0.0018 17.9 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain NB-ARC PF00931.17 KUM58655.1 - 0.0017 17.3 0.0 0.0052 15.6 0.0 1.8 1 0 0 1 1 1 1 NB-ARC domain NicO PF03824.11 KUM58657.1 - 1.2e-58 198.6 15.9 1.1e-54 185.7 5.2 2.3 2 0 0 2 2 2 2 High-affinity nickel-transport protein MIG-14_Wnt-bd PF06664.7 KUM58657.1 - 0.11 11.2 5.0 0.037 12.8 0.9 2.0 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion DUF3481 PF11980.3 KUM58657.1 - 0.19 11.5 1.4 2.8 7.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3481) DUF2975 PF11188.3 KUM58657.1 - 2.8 7.6 11.4 2.3 7.9 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2975) AA_permease PF00324.16 KUM58658.1 - 1.4e-123 412.7 37.7 1.8e-123 412.4 26.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KUM58658.1 - 2.6e-38 131.6 39.4 3.3e-38 131.3 27.3 1.1 1 0 0 1 1 1 1 Amino acid permease Pox_A14 PF05767.7 KUM58658.1 - 0.69 9.9 4.8 5.8 6.9 0.1 3.5 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Sugar_tr PF00083.19 KUM58659.1 - 6.8e-47 160.0 9.1 7.4e-47 159.9 6.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM58659.1 - 1.4e-09 37.1 6.6 2.1e-09 36.5 4.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily PAP2_3 PF14378.1 KUM58659.1 - 1.3 8.5 5.4 0.096 12.1 0.2 1.8 2 0 0 2 2 2 0 PAP2 superfamily Metallophos PF00149.23 KUM58661.1 - 2.9e-10 39.8 0.2 9.9e-10 38.1 0.2 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KUM58661.1 - 1.3e-05 25.0 0.1 2.6e-05 24.1 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Epimerase_2 PF02350.14 KUM58661.1 - 0.21 10.3 0.0 0.33 9.6 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Exo_endo_phos PF03372.18 KUM58662.1 - 1.6e-18 67.5 0.1 1.6e-18 67.5 0.1 2.0 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 KUM58662.1 - 1e-14 53.7 9.9 1.1e-08 34.4 1.7 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KUM58662.1 - 2.9e-10 39.7 5.1 1.7e-08 34.1 4.2 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KUM58662.1 - 4.6e-07 28.9 5.7 0.015 15.2 0.1 5.0 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 KUM58662.1 - 0.0006 19.6 9.7 0.36 11.2 0.2 4.8 4 0 0 4 4 4 2 Leucine rich repeat tRNA-synt_1 PF00133.17 KUM58663.1 - 2e-38 131.8 0.0 1.7e-27 95.6 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KUM58663.1 - 1.5e-19 69.9 0.3 5.2e-12 45.1 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KUM58663.1 - 2.4e-17 63.0 0.1 2e-16 60.0 0.0 2.4 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KUM58663.1 - 1.3e-07 31.0 0.0 2.4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 KUM58663.1 - 0.0022 16.7 0.0 0.094 11.3 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (K) GATA PF00320.22 KUM58664.1 - 9e-16 56.9 5.9 1.8e-15 55.9 4.1 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_9 PF13426.1 KUM58664.1 - 1.3e-09 38.3 0.0 5.8e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.6 KUM58664.1 - 8.5e-09 35.4 0.0 1.9e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 KUM58664.1 - 1.5e-07 31.1 0.1 1e-06 28.4 0.0 2.3 2 1 0 2 2 2 1 PAS fold PAS_4 PF08448.5 KUM58664.1 - 3.1e-06 27.1 0.0 7.1e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.1 KUM58664.1 - 0.00029 20.7 0.0 0.00066 19.6 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.1 KUM58664.1 - 0.0029 17.4 0.0 0.0073 16.1 0.0 1.7 1 1 0 1 1 1 1 PAS domain Aminotran_1_2 PF00155.16 KUM58665.1 - 1e-40 139.8 0.0 4.7e-40 137.6 0.0 1.7 1 1 1 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KUM58665.1 - 4.2e-06 26.1 0.0 8e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_3 PF00202.16 KUM58665.1 - 0.12 11.2 0.0 0.53 9.0 0.0 2.0 3 0 0 3 3 3 0 Aminotransferase class-III DUF1448 PF07289.6 KUM58665.1 - 0.17 10.7 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1448) NAD_binding_1 PF00175.16 KUM58668.1 - 5.2e-07 30.2 0.0 0.016 15.7 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KUM58668.1 - 9.9e-06 25.5 0.1 0.00014 21.7 0.1 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 KUM58668.1 - 0.097 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain HAD PF12710.2 KUM58669.1 - 2.9e-13 50.3 0.0 3.8e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KUM58669.1 - 1.5e-05 25.2 0.0 3.8e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 KUM58669.1 - 0.0049 16.0 0.0 0.092 11.8 0.0 2.0 2 0 0 2 2 2 1 Putative Phosphatase UMPH-1 PF05822.7 KUM58669.1 - 0.064 12.5 0.0 0.13 11.5 0.0 1.4 1 1 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) SpoU_sub_bind PF08032.7 KUM58669.1 - 0.11 12.7 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding FMN_red PF03358.10 KUM58670.1 - 5.2e-25 87.7 0.0 7.1e-25 87.2 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 KUM58670.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin-like fold Abhydrolase_6 PF12697.2 KUM58671.1 - 4.8e-21 75.6 0.1 6.2e-21 75.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KUM58671.1 - 4.4e-16 58.4 0.0 1.3e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 KUM58671.1 - 4.2e-13 49.2 0.0 1.3e-12 47.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM58671.1 - 0.00026 20.6 0.0 0.0053 16.3 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.13 KUM58671.1 - 0.0016 17.7 0.0 0.0072 15.6 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 KUM58671.1 - 0.007 15.6 0.0 0.054 12.6 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S10 PF00450.17 KUM58671.1 - 0.0075 15.4 0.0 2.7 7.0 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase Abhydrolase_2 PF02230.11 KUM58671.1 - 0.015 14.7 0.0 0.068 12.5 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 KUM58671.1 - 0.14 11.7 0.0 0.34 10.5 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 3) SbcCD_C PF13558.1 KUM58672.1 - 8.7e-12 44.8 0.0 3.9e-11 42.7 0.0 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 KUM58672.1 - 3.3e-05 24.0 6.5 0.0019 18.1 0.0 3.6 2 1 0 2 2 2 1 AAA domain AAA_13 PF13166.1 KUM58672.1 - 0.0024 16.4 27.2 0.0024 16.4 18.8 6.2 1 1 5 6 6 6 3 AAA domain KNOX2 PF03791.8 KUM58672.1 - 0.0027 16.9 0.1 0.2 10.9 0.2 3.4 2 0 0 2 2 2 1 KNOX2 domain GCD14 PF08704.5 KUM58673.1 - 2.5e-08 33.7 0.0 0.00078 19.0 0.0 2.3 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.2 KUM58673.1 - 0.017 15.6 0.0 8.7 6.9 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain L51_S25_CI-B8 PF05047.11 KUM58674.1 - 1.6e-21 75.7 0.0 3.3e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain COesterase PF00135.23 KUM58675.1 - 2e-95 320.5 0.3 3.4e-86 290.0 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KUM58675.1 - 3.5e-14 52.8 0.1 5.1e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KUM58675.1 - 0.00025 20.8 0.1 0.00043 20.0 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Fungal_trans PF04082.13 KUM58676.1 - 2.5e-18 65.9 0.3 6.8e-18 64.4 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Iso_dh PF00180.15 KUM58677.1 - 1.3e-83 280.8 0.0 1.4e-83 280.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PRK PF00485.13 KUM58678.1 - 4.9e-06 26.2 0.0 0.014 15.0 0.0 2.2 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 KUM58678.1 - 4.3e-05 24.3 0.1 0.0016 19.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KUM58678.1 - 0.00013 22.0 0.1 0.00039 20.4 0.0 1.8 2 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 KUM58678.1 - 0.00035 19.7 0.0 0.00085 18.4 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin ArgK PF03308.11 KUM58678.1 - 0.0012 17.7 0.0 0.0019 17.0 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_33 PF13671.1 KUM58678.1 - 0.0013 18.5 0.0 0.0055 16.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KUM58678.1 - 0.0014 18.1 0.2 0.0038 16.7 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain APS_kinase PF01583.15 KUM58678.1 - 0.0057 16.3 0.1 0.025 14.2 0.0 1.9 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_18 PF13238.1 KUM58678.1 - 0.0085 16.3 0.1 0.038 14.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KUM58678.1 - 0.012 15.4 0.0 0.033 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 KUM58678.1 - 0.013 14.4 0.0 0.043 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) KTI12 PF08433.5 KUM58678.1 - 0.031 13.4 0.0 0.06 12.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ABC_tran PF00005.22 KUM58678.1 - 0.049 13.9 0.0 0.096 12.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF4432 PF14486.1 KUM58678.1 - 0.073 11.6 0.1 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) MobB PF03205.9 KUM58678.1 - 0.12 12.1 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 KUM58678.1 - 0.15 11.7 0.1 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 NTPase SKG6 PF08693.5 KUM58679.1 - 6.7e-07 28.5 0.2 6.7e-07 28.5 0.1 1.7 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Glycophorin_A PF01102.13 KUM58679.1 - 0.0012 18.6 3.1 0.0047 16.6 2.1 2.0 1 1 0 1 1 1 1 Glycophorin A Syndecan PF01034.15 KUM58679.1 - 0.0089 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Syndecan domain Herpes_gE PF02480.11 KUM58679.1 - 0.011 14.0 0.0 0.012 13.9 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SSP160 PF06933.6 KUM58679.1 - 0.014 13.3 4.7 0.018 13.0 3.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Podoplanin PF05808.6 KUM58679.1 - 0.021 14.3 1.1 0.029 13.9 0.7 1.2 1 0 0 1 1 1 0 Podoplanin gpUL132 PF11359.3 KUM58679.1 - 0.075 12.3 2.8 0.11 11.7 1.9 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 Nitrate_red_gam PF02665.9 KUM58679.1 - 0.14 11.4 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit EphA2_TM PF14575.1 KUM58679.1 - 0.15 12.4 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DHO_dh PF01180.16 KUM58681.1 - 8.5e-67 225.1 0.0 6.9e-65 218.9 0.0 2.1 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 KUM58681.1 - 3.2e-07 29.5 0.0 2.8e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 FMN-dependent dehydrogenase PcrB PF01884.12 KUM58681.1 - 1.3e-05 24.6 0.3 0.087 12.0 0.0 2.3 2 0 0 2 2 2 2 PcrB family TIM PF00121.13 KUM58682.1 - 7.9e-44 149.5 0.0 1e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase IL13 PF03487.8 KUM58682.1 - 0.26 11.0 1.6 0.5 10.1 0.6 1.9 1 1 0 1 1 1 0 Interleukin-13 LacAB_rpiB PF02502.13 KUM58683.1 - 7.6e-43 145.5 0.0 8.7e-43 145.3 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase URO-D PF01208.12 KUM58683.1 - 0.024 13.5 0.1 0.083 11.7 0.0 1.7 2 0 0 2 2 2 0 Uroporphyrinogen decarboxylase (URO-D) U-box PF04564.10 KUM58684.1 - 4.3e-21 74.6 0.0 8.1e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 KUM58684.1 - 3.9e-17 61.6 3.0 6.3e-15 54.5 0.2 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KUM58684.1 - 3e-09 36.0 4.2 7.5e-05 22.3 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KUM58684.1 - 2.1e-08 33.4 2.1 1.2e-05 24.7 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KUM58684.1 - 9e-08 32.5 2.4 0.001 19.6 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KUM58684.1 - 2.3e-05 24.6 6.0 0.0059 17.1 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KUM58684.1 - 5.2e-05 23.4 1.1 0.01 16.1 0.0 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KUM58684.1 - 0.00033 20.6 2.7 0.086 13.0 0.0 3.4 3 1 1 4 4 2 1 Tetratricopeptide repeat Apc3 PF12895.2 KUM58684.1 - 0.0019 18.2 0.3 0.0043 17.1 0.2 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KUM58684.1 - 0.0051 16.7 2.6 0.63 10.0 0.4 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.7 KUM58684.1 - 0.21 11.4 2.0 0.38 10.6 0.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KUM58684.1 - 0.63 9.9 3.3 1.4 8.8 0.0 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat ACBP PF00887.14 KUM58685.1 - 1.6e-13 50.1 0.4 2.5e-13 49.4 0.3 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Tyr-DNA_phospho PF06087.7 KUM58686.1 - 2.8e-150 500.8 0.0 3.3e-150 500.5 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 KUM58686.1 - 0.00074 19.2 0.0 0.34 10.6 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain Gly_transf_sug PF04488.10 KUM58687.1 - 4.5e-06 26.9 0.0 8.6e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 KUM58687.1 - 0.06 12.5 0.0 0.088 11.9 0.0 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein RRN3 PF05327.6 KUM58688.1 - 4.2e-177 589.6 0.0 5.4e-177 589.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Actin PF00022.14 KUM58691.1 - 5.8e-32 110.5 0.0 2.1e-18 65.9 0.0 2.6 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 KUM58691.1 - 5.6e-06 25.1 0.0 0.00044 18.9 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DUF1136 PF06582.7 KUM58691.1 - 0.047 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Repeat of unknown function (DUF1136) DUF2114 PF09887.4 KUM58691.1 - 0.12 10.6 0.1 0.16 10.2 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) Paf1 PF03985.8 KUM58692.1 - 3.6e-37 128.1 0.6 1.6e-24 86.4 0.0 2.9 2 1 0 2 2 2 2 Paf1 ADH_zinc_N PF00107.21 KUM58693.1 - 2.7e-28 98.0 0.3 3.6e-28 97.6 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KUM58693.1 - 4.4e-13 50.2 0.1 6.4e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM58693.1 - 1.3e-06 28.0 0.3 2.4e-06 27.2 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 KUM58693.1 - 0.025 15.1 0.3 0.4 11.2 0.2 2.4 1 1 0 1 1 1 0 Methyltransferase domain Glucokinase PF02685.11 KUM58693.1 - 0.044 12.5 0.1 0.078 11.7 0.1 1.3 1 0 0 1 1 1 0 Glucokinase Arf PF00025.16 KUM58694.1 - 5.2e-70 234.2 0.1 6.1e-70 233.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KUM58694.1 - 3e-10 39.6 0.0 3.9e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KUM58694.1 - 1.4e-09 37.5 0.0 1.8e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KUM58694.1 - 1.4e-09 37.1 0.5 1.1e-05 24.3 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KUM58694.1 - 2.2e-07 30.2 0.0 4e-07 29.4 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KUM58694.1 - 3.9e-06 27.3 0.0 8.2e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KUM58694.1 - 1.1e-05 24.9 0.1 0.0035 16.8 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KUM58694.1 - 3.9e-05 23.5 0.0 5.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KUM58694.1 - 0.038 13.2 0.4 0.26 10.5 0.3 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF3986 PF13143.1 KUM58694.1 - 0.077 13.4 0.1 0.16 12.4 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) ADH_N PF08240.7 KUM58695.1 - 6.3e-26 90.2 0.0 1.6e-25 88.9 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM58695.1 - 4.5e-19 68.2 1.3 6.8e-19 67.7 0.9 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KUM58695.1 - 6.8e-05 23.7 0.0 0.00012 22.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Hydrolase_like PF13242.1 KUM58695.1 - 0.088 12.5 0.1 0.38 10.4 0.0 2.1 2 0 0 2 2 2 0 HAD-hyrolase-like ISN1 PF06437.6 KUM58696.1 - 2e-193 642.6 0.0 2.3e-193 642.5 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Med17 PF10156.4 KUM58697.1 - 5.7e-123 410.6 0.6 7.6e-123 410.2 0.4 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex DAO PF01266.19 KUM58698.1 - 9.7e-43 146.4 0.1 1.2e-42 146.1 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KUM58698.1 - 5.2e-05 23.2 0.5 0.00015 21.7 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KUM58698.1 - 8.5e-05 22.3 0.0 0.0022 17.8 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KUM58698.1 - 0.029 13.2 0.0 0.12 11.3 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KUM58698.1 - 0.037 14.0 0.0 0.85 9.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KUM58698.1 - 0.054 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 KUM58698.1 - 0.091 11.5 1.6 0.15 10.8 1.1 1.6 1 1 0 1 1 1 0 FAD binding domain adh_short PF00106.20 KUM58699.1 - 3.9e-12 46.3 0.0 6.4e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM58699.1 - 2.4e-07 30.7 0.0 2.9e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_hydro_76 PF03663.9 KUM58700.1 - 4.9e-157 523.0 23.0 6.2e-157 522.7 15.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF4571 PF15137.1 KUM58700.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4571) SurE PF01975.12 KUM58701.1 - 9.2e-33 113.2 0.3 1.2e-32 112.7 0.2 1.2 1 0 0 1 1 1 1 Survival protein SurE ABC2_membrane PF01061.19 KUM58702.1 - 5.1e-85 283.8 52.1 2.3e-49 167.4 13.9 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KUM58702.1 - 3.2e-40 137.5 0.0 1.2e-18 67.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KUM58702.1 - 1.1e-24 86.0 0.1 1.1e-24 86.0 0.0 3.9 4 0 0 4 4 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 KUM58702.1 - 1.8e-09 37.1 36.8 4.5e-09 35.8 13.2 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 KUM58702.1 - 7.9e-09 35.8 0.0 0.052 13.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KUM58702.1 - 6.9e-07 29.4 0.1 0.0016 18.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 KUM58702.1 - 1.8e-06 27.5 0.3 0.0087 15.4 0.0 3.5 2 1 1 3 3 3 1 AAA domain SMC_N PF02463.14 KUM58702.1 - 4.5e-05 22.7 0.0 0.017 14.3 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KUM58702.1 - 7.3e-05 22.0 0.0 0.0025 16.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 UPF0079 PF02367.12 KUM58702.1 - 7.6e-05 22.3 0.3 0.036 13.7 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 KUM58702.1 - 9.6e-05 22.5 0.0 0.09 12.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KUM58702.1 - 0.00021 21.5 0.0 0.091 13.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 KUM58702.1 - 0.00049 19.5 0.2 0.0063 16.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 KUM58702.1 - 0.00098 18.8 0.0 1.4 8.5 0.0 2.4 2 0 0 2 2 2 2 Archaeal ATPase NACHT PF05729.7 KUM58702.1 - 0.0036 16.9 0.2 0.27 10.8 0.0 3.3 3 0 0 3 3 3 1 NACHT domain AAA_28 PF13521.1 KUM58702.1 - 0.0049 16.8 0.0 0.038 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KUM58702.1 - 0.0074 17.1 0.0 0.076 13.8 0.0 2.7 3 0 0 3 3 2 1 AAA domain cobW PF02492.14 KUM58702.1 - 0.008 15.6 0.1 0.34 10.3 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 KUM58702.1 - 0.009 16.5 0.0 1.4 9.4 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_19 PF13245.1 KUM58702.1 - 0.01 15.5 0.2 1.4 8.7 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain PduV-EutP PF10662.4 KUM58702.1 - 0.018 14.5 0.0 0.71 9.3 0.0 2.6 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 KUM58702.1 - 0.028 14.2 0.0 0.2 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KUM58702.1 - 0.044 13.2 0.0 4.7 6.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 KUM58702.1 - 0.081 12.8 0.0 9.9 6.1 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.1 KUM58702.1 - 0.12 12.2 0.0 0.76 9.7 0.0 2.2 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 KUM58702.1 - 0.13 12.5 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KUM58702.1 - 0.3 10.6 0.0 1.3 8.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain NPP1 PF05630.6 KUM58703.1 - 4.3e-54 183.3 0.0 4.9e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) YjbE PF11106.3 KUM58703.1 - 0.7 9.8 4.5 4.4 7.3 0.5 2.6 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE Sugar_tr PF00083.19 KUM58704.1 - 8.2e-79 265.2 22.4 1e-78 264.9 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM58704.1 - 5.3e-15 54.9 58.0 1.5e-13 50.1 20.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2456 PF10445.4 KUM58704.1 - 0.46 10.4 5.0 0.83 9.6 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) DUF4646 PF15496.1 KUM58705.1 - 2.7e-15 56.5 0.0 5e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) Erf4 PF10256.4 KUM58705.1 - 0.086 12.7 0.0 0.26 11.1 0.0 1.7 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Fungal_trans PF04082.13 KUM58706.1 - 8e-10 38.0 0.1 1.4e-09 37.2 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KUM58707.1 - 5.8e-31 107.4 32.9 7.3e-31 107.1 22.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PFK PF00365.15 KUM58708.1 - 7.8e-164 543.4 2.4 1.6e-117 391.5 0.5 2.1 2 0 0 2 2 2 2 Phosphofructokinase NAD_kinase PF01513.16 KUM58708.1 - 0.097 11.4 0.2 1 8.0 0.1 2.2 2 0 0 2 2 2 0 ATP-NAD kinase DUF4646 PF15496.1 KUM58708.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) SKG6 PF08693.5 KUM58709.1 - 0.046 13.0 0.9 0.079 12.2 0.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DNA_ligase_A_M PF01068.16 KUM58710.1 - 3.2e-22 78.9 0.0 7.1e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KUM58710.1 - 1.7e-08 34.5 0.0 3.3e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus Fungal_trans PF04082.13 KUM58711.1 - 5e-14 51.8 0.2 8.9e-14 50.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM58711.1 - 5e-06 26.3 12.0 5e-06 26.3 8.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4066 PF13278.1 KUM58712.1 - 1.2e-21 76.6 0.1 2e-21 75.9 0.1 1.3 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KUM58712.1 - 1e-05 25.0 0.0 2.3e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family polyprenyl_synt PF00348.12 KUM58713.1 - 1.5e-74 250.1 0.0 1.7e-74 249.9 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase GatB_Yqey PF02637.13 KUM58713.1 - 0.095 12.4 1.7 0.24 11.1 1.2 1.7 1 0 0 1 1 1 0 GatB domain SEP PF08059.8 KUM58714.1 - 3.8e-28 97.6 0.1 6.7e-28 96.8 0.0 1.4 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 KUM58714.1 - 2.9e-14 52.8 0.0 5.1e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 KUM58714.1 - 6.2e-13 48.0 3.4 1e-12 47.3 2.4 1.4 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.26 KUM58714.1 - 0.028 14.2 0.2 0.049 13.5 0.1 1.4 1 0 0 1 1 1 0 UBA/TS-N domain DUF605 PF04652.11 KUM58714.1 - 0.48 9.7 9.3 0.74 9.1 6.4 1.3 1 0 0 1 1 1 0 Vta1 like Pap_E4 PF02711.9 KUM58714.1 - 5 8.0 7.1 6.8 7.5 0.9 2.5 2 0 0 2 2 2 0 E4 protein APC8 PF04049.8 KUM58716.1 - 7.7e-53 178.0 0.2 2.3e-52 176.5 0.0 1.9 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 KUM58716.1 - 7e-22 76.0 8.1 0.00035 20.0 0.0 7.8 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 KUM58716.1 - 9.9e-22 76.3 9.3 5.9e-07 29.0 0.0 6.5 4 2 2 6 6 6 4 TPR repeat TPR_2 PF07719.12 KUM58716.1 - 3.9e-18 63.8 20.0 0.069 13.1 2.0 9.5 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.1 KUM58716.1 - 6.8e-18 64.8 16.0 6.5e-05 23.4 0.4 7.2 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 KUM58716.1 - 4.2e-17 60.5 10.4 0.00076 19.0 0.0 7.6 7 1 2 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 KUM58716.1 - 5.2e-16 57.6 14.8 0.0076 16.7 0.0 9.0 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.1 KUM58716.1 - 1e-10 41.2 10.7 6.2e-05 22.7 0.2 5.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 KUM58716.1 - 1.5e-10 40.8 24.0 0.028 14.3 0.0 7.4 5 2 3 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 KUM58716.1 - 3.3e-10 40.1 16.2 0.042 14.2 0.1 8.0 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 KUM58716.1 - 6.6e-10 38.4 5.5 0.28 11.4 0.0 7.1 7 1 0 7 7 6 2 Tetratricopeptide repeat Apc3 PF12895.2 KUM58716.1 - 1.9e-09 37.5 12.9 0.25 11.4 0.0 6.2 8 0 0 8 8 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KUM58716.1 - 5e-08 32.1 9.0 1.1 9.2 0.0 6.7 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 KUM58716.1 - 0.00011 22.3 27.1 0.73 10.4 0.2 9.6 11 0 0 11 11 9 1 Tetratricopeptide repeat TPR_15 PF13429.1 KUM58716.1 - 0.00079 18.5 11.0 0.0024 16.9 3.2 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat PPR_3 PF13812.1 KUM58716.1 - 0.011 15.9 0.1 1.2 9.5 0.0 3.4 3 0 0 3 3 2 0 Pentatricopeptide repeat domain ChAPs PF09295.5 KUM58716.1 - 0.012 14.3 0.1 7.2 5.2 0.0 3.0 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 KUM58716.1 - 0.1 12.5 18.1 18 5.4 0.0 6.8 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 KUM58716.1 - 1.3 9.6 6.6 1.7 9.3 0.5 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat PHO4 PF01384.15 KUM58717.1 - 1.3e-108 362.5 11.9 1.7e-108 362.1 8.2 1.1 1 0 0 1 1 1 1 Phosphate transporter family SpoVAB PF13782.1 KUM58717.1 - 0.021 14.7 4.2 0.059 13.3 0.7 2.9 2 0 0 2 2 2 0 Stage V sporulation protein AB Adeno_E3_CR2 PF02439.10 KUM58717.1 - 0.81 9.2 4.5 0.9 9.1 1.1 2.5 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 ParA PF10609.4 KUM58718.1 - 5.8e-34 115.8 0.0 1e-33 115.0 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KUM58718.1 - 1.1e-13 51.0 0.0 1.7e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 KUM58718.1 - 6.1e-07 28.7 0.0 5.4e-06 25.6 0.0 1.9 1 1 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.1 KUM58718.1 - 4.6e-05 23.3 0.1 0.00013 21.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 KUM58718.1 - 0.00014 20.9 1.4 0.00025 20.2 1.0 1.3 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_25 PF13481.1 KUM58718.1 - 0.00027 20.3 0.2 0.00057 19.3 0.2 1.5 1 0 0 1 1 1 1 AAA domain YhjQ PF06564.7 KUM58718.1 - 0.00051 19.4 0.8 0.0026 17.1 0.4 2.3 1 1 1 2 2 2 1 YhjQ protein ArgK PF03308.11 KUM58718.1 - 0.0029 16.4 0.5 0.0048 15.7 0.4 1.3 1 0 0 1 1 1 1 ArgK protein AAA_26 PF13500.1 KUM58718.1 - 0.0066 16.0 0.9 0.5 9.9 0.4 2.2 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 KUM58718.1 - 0.067 12.8 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase UIM PF02809.15 KUM58718.1 - 0.16 11.5 0.3 0.16 11.5 0.2 2.2 2 0 0 2 2 1 0 Ubiquitin interaction motif DUF258 PF03193.11 KUM58718.1 - 0.72 9.0 3.0 0.54 9.4 1.0 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Glyco_transf_90 PF05686.7 KUM58719.1 - 6e-29 100.9 0.6 8e-29 100.5 0.4 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 p450 PF00067.17 KUM58720.1 - 9.5e-49 166.1 0.0 1.2e-48 165.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 bZIP_1 PF00170.16 KUM58721.1 - 0.00077 19.3 8.3 0.0011 18.8 5.8 1.2 1 0 0 1 1 1 1 bZIP transcription factor DIT1_PvcA PF05141.7 KUM58722.1 - 4e-90 301.9 0.0 5.6e-90 301.4 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.11 KUM58722.1 - 4.9e-27 95.2 0.0 7.7e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Lon_C PF05362.8 KUM58724.1 - 4.3e-64 215.6 0.0 8.8e-64 214.5 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 KUM58724.1 - 7.3e-37 127.0 0.0 1.7e-36 125.8 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 KUM58724.1 - 6.4e-22 78.1 0.0 1.4e-21 77.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KUM58724.1 - 2.1e-07 30.7 0.0 4.1e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 KUM58724.1 - 2.6e-06 26.9 0.0 6.4e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.9 KUM58724.1 - 3.3e-06 27.1 0.0 9.4e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.6 KUM58724.1 - 5.8e-06 25.2 0.2 1.3e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain AAA_22 PF13401.1 KUM58724.1 - 8.2e-06 25.9 0.1 0.00015 21.8 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KUM58724.1 - 3.8e-05 23.7 0.1 0.00047 20.1 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KUM58724.1 - 4.9e-05 24.1 0.1 0.00024 21.9 0.0 2.2 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 KUM58724.1 - 0.00031 19.8 0.0 0.0011 18.0 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KUM58724.1 - 0.0021 17.9 0.0 0.0048 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KUM58724.1 - 0.0025 18.1 1.6 0.018 15.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain ATP-synt_ab PF00006.20 KUM58724.1 - 0.016 14.7 0.2 0.073 12.5 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.12 KUM58724.1 - 0.02 14.3 0.0 0.047 13.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.10 KUM58724.1 - 0.042 13.5 0.1 0.37 10.4 0.0 2.3 1 1 1 2 2 2 0 NTPase RNA_helicase PF00910.17 KUM58724.1 - 0.053 13.6 0.0 0.17 12.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase DUF258 PF03193.11 KUM58724.1 - 0.055 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 KUM58724.1 - 0.058 12.7 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Phage_connect_1 PF05135.8 KUM58724.1 - 0.063 13.4 0.6 0.37 11.0 0.0 2.3 2 0 0 2 2 2 0 Phage gp6-like head-tail connector protein AAA_24 PF13479.1 KUM58724.1 - 0.079 12.5 0.1 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KUM58724.1 - 0.092 12.5 0.2 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 KUM58724.1 - 0.14 12.4 1.7 0.34 11.2 0.0 2.2 2 0 0 2 2 2 0 ABC transporter UPF0079 PF02367.12 KUM58724.1 - 0.14 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 UPF0014 PF03649.8 KUM58725.1 - 0.024 13.8 1.8 0.024 13.8 1.3 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0014) TspO_MBR PF03073.10 KUM58725.1 - 0.17 11.3 8.3 2.7 7.5 0.1 2.3 2 0 0 2 2 2 0 TspO/MBR family Secretin PF00263.16 KUM58726.1 - 0.0015 17.9 0.3 10 5.4 0.0 3.4 3 0 0 3 3 3 3 Bacterial type II and III secretion system protein Dicistro_VP4 PF11492.3 KUM58726.1 - 0.012 15.5 0.0 30 4.6 0.0 3.5 3 0 0 3 3 3 0 Cricket paralysis virus, VP4 Rad4 PF03835.10 KUM58727.1 - 2.9e-32 111.0 0.0 2.9e-32 111.0 0.0 1.8 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 KUM58727.1 - 5.4e-29 99.7 0.1 9.7e-29 98.9 0.1 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 KUM58727.1 - 3.5e-17 61.6 0.0 7.7e-17 60.5 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 KUM58727.1 - 3.6e-16 59.2 0.4 3.8e-15 55.9 0.0 2.8 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 KUM58727.1 - 0.0014 18.8 0.0 0.0041 17.3 0.0 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily CoA_binding_2 PF13380.1 KUM58729.1 - 7.4e-27 93.8 0.0 9.4e-27 93.4 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain Mob1_phocein PF03637.12 KUM58730.1 - 2.6e-20 72.7 0.2 4.8e-20 71.9 0.1 1.3 1 0 0 1 1 1 1 Mob1/phocein family HIT PF01230.18 KUM58731.1 - 2.3e-24 85.7 0.1 4e-24 85.0 0.1 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KUM58731.1 - 4e-07 30.2 0.0 5.7e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HD_3 PF13023.1 KUM58732.1 - 2e-47 160.9 0.1 2.5e-47 160.6 0.1 1.1 1 0 0 1 1 1 1 HD domain HAUS6_N PF14661.1 KUM58733.1 - 2.7e-14 53.1 0.0 4.9e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus BRO1 PF03097.13 KUM58734.1 - 2.3e-121 405.1 0.3 2.3e-121 405.1 0.2 2.5 3 1 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KUM58734.1 - 3.5e-89 298.6 16.2 3.5e-89 298.6 11.2 1.8 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Sas10 PF09368.5 KUM58734.1 - 0.042 14.0 0.9 0.12 12.5 0.6 1.7 1 0 0 1 1 1 0 Sas10 C-terminal domain HCMV_UL139 PF12507.3 KUM58734.1 - 0.56 10.3 7.1 2.6 8.2 2.3 3.6 2 2 0 2 2 2 0 Human Cytomegalovirus UL139 protein Takusan PF04822.8 KUM58734.1 - 1.6 8.5 9.0 6.7 6.5 1.1 2.8 2 0 0 2 2 2 0 Takusan BLOC1_2 PF10046.4 KUM58734.1 - 4 7.6 8.9 1.2 9.2 0.1 3.9 3 1 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AATF-Che1 PF13339.1 KUM58734.1 - 6.5 6.9 11.4 5.9 7.0 1.4 3.2 3 1 0 3 3 3 0 Apoptosis antagonizing transcription factor cobW PF02492.14 KUM58735.1 - 1.9e-45 154.4 0.2 2.6e-45 154.0 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 KUM58735.1 - 9.2e-05 22.0 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain Arch_ATPase PF01637.13 KUM58735.1 - 0.0071 16.0 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 KUM58735.1 - 0.02 14.8 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 KUM58735.1 - 0.031 14.5 0.0 0.072 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KUM58735.1 - 0.032 14.1 0.2 0.099 12.6 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase T2SE PF00437.15 KUM58735.1 - 0.032 13.1 0.1 0.066 12.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 KUM58735.1 - 0.038 13.5 0.1 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain ArgK PF03308.11 KUM58735.1 - 0.039 12.7 1.0 0.68 8.6 0.0 2.6 3 0 0 3 3 3 0 ArgK protein AAA_19 PF13245.1 KUM58735.1 - 0.045 13.4 0.1 0.097 12.4 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain ATP_bind_1 PF03029.12 KUM58735.1 - 0.053 13.0 2.8 0.94 8.9 1.9 2.2 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein MobB PF03205.9 KUM58735.1 - 0.056 13.1 0.5 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KUM58735.1 - 0.069 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_23 PF13476.1 KUM58735.1 - 0.083 13.2 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KUM58735.1 - 0.083 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KUM58735.1 - 0.092 13.2 0.2 0.59 10.6 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein Zeta_toxin PF06414.7 KUM58735.1 - 0.1 11.6 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Septin PF00735.13 KUM58735.1 - 0.11 11.5 0.6 10 5.0 0.1 2.2 2 0 0 2 2 2 0 Septin ABC_tran PF00005.22 KUM58735.1 - 0.13 12.6 0.1 0.37 11.0 0.0 1.8 2 0 0 2 2 1 0 ABC transporter AAA_30 PF13604.1 KUM58735.1 - 0.17 11.4 0.8 3.4 7.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Pkinase_Tyr PF07714.12 KUM58736.1 - 1.7e-09 37.1 0.0 1.1e-08 34.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KUM58736.1 - 5e-08 32.4 0.0 5.7e-07 28.9 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Prok_Ub PF14454.1 KUM58736.1 - 0.34 10.5 2.6 0.39 10.4 0.6 1.9 2 0 0 2 2 2 0 Prokaryotic Ubiquitin SAP30_Sin3_bdg PF13867.1 KUM58737.1 - 5.1e-15 55.0 0.1 1.3e-13 50.6 0.0 2.4 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 CTDII PF01556.13 KUM58738.1 - 1.6e-26 92.0 2.5 1.5e-20 72.8 0.3 3.3 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 KUM58738.1 - 2.5e-23 81.5 4.6 4.4e-23 80.7 3.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KUM58738.1 - 7.6e-11 41.9 18.5 1.5e-10 40.9 12.8 1.5 1 0 0 1 1 1 1 DnaJ central domain Thiolase_N PF00108.18 KUM58739.1 - 1.3e-96 322.6 0.2 1.8e-96 322.1 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KUM58739.1 - 3.9e-44 149.0 2.9 4.1e-44 148.9 1.0 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KUM58739.1 - 7.2e-06 25.6 3.4 9.1e-06 25.3 1.1 2.2 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KUM58739.1 - 0.04 13.5 2.1 0.14 11.8 0.1 2.6 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GTP_EFTU PF00009.22 KUM58740.1 - 1.6e-43 148.3 0.0 2.4e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KUM58740.1 - 4.8e-27 93.8 0.0 1.1e-26 92.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KUM58740.1 - 1.1e-19 70.0 0.0 2.8e-19 68.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KUM58740.1 - 4.6e-11 42.6 0.0 1.2e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KUM58740.1 - 5.4e-07 29.3 0.2 3.3e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 KUM58740.1 - 9.3e-07 28.8 0.1 1.8e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KUM58740.1 - 9.9e-05 22.8 0.0 0.0003 21.2 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein Ras PF00071.17 KUM58740.1 - 0.0055 16.1 0.0 0.028 13.8 0.0 2.1 1 1 0 1 1 1 1 Ras family Dynamin_N PF00350.18 KUM58740.1 - 0.018 14.9 0.1 4.9 6.9 0.1 2.5 1 1 1 2 2 2 0 Dynamin family DUF330 PF03886.8 KUM58741.1 - 0.007 15.7 0.3 0.0089 15.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF330) LOH1CR12 PF10158.4 KUM58741.1 - 0.34 10.6 2.9 0.28 10.9 1.3 1.4 2 0 0 2 2 2 0 Tumour suppressor protein DUF59 PF01883.14 KUM58742.1 - 7.8e-06 25.7 0.1 1.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF59 Zip PF02535.17 KUM58743.1 - 1.6e-29 102.9 0.1 2.1e-29 102.5 0.1 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Amidohydro_4 PF13147.1 KUM58744.1 - 2.1e-12 47.6 3.2 2.9e-11 43.9 2.2 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KUM58744.1 - 1.2e-11 44.9 0.0 8.9e-11 42.0 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KUM58744.1 - 1.4e-06 27.8 0.0 2.8e-06 26.8 0.0 1.5 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 KUM58744.1 - 0.00011 21.9 0.0 0.00032 20.4 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase GMC_oxred_N PF00732.14 KUM58745.1 - 6.9e-53 179.7 0.0 8.8e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KUM58745.1 - 1.3e-38 132.5 0.0 1.9e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KUM58745.1 - 5.9e-07 28.6 0.1 0.0099 14.7 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KUM58745.1 - 3.2e-06 26.2 0.0 0.0021 17.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KUM58745.1 - 0.00035 20.5 0.1 0.0014 18.6 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KUM58745.1 - 0.0024 16.8 0.0 0.0035 16.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 KUM58745.1 - 0.0071 15.4 0.2 0.21 10.5 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KUM58745.1 - 0.024 14.5 0.0 0.063 13.1 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KUM58745.1 - 0.025 14.6 0.1 0.36 10.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KUM58745.1 - 0.27 10.0 0.2 1.3 7.8 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A MFS_1 PF07690.11 KUM58746.1 - 1e-16 60.6 30.9 1.5e-16 60.0 21.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KUM58746.1 - 5.8e-10 38.8 5.6 5.8e-10 38.8 3.9 2.8 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 DUF4660 PF15559.1 KUM58746.1 - 0.037 14.1 0.3 0.069 13.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4660) CPSF_A PF03178.10 KUM58747.1 - 8.6e-100 333.9 0.0 2.1e-99 332.6 0.0 1.7 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 KUM58747.1 - 2.9e-07 29.0 0.2 0.0096 14.1 0.1 2.5 3 0 0 3 3 3 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term LMBR1 PF04791.11 KUM58748.1 - 1.8e-18 66.3 12.6 2.9e-18 65.7 1.1 2.2 2 0 0 2 2 2 2 LMBR1-like membrane protein DUF3592 PF12158.3 KUM58748.1 - 1.2 8.8 0.0 1.2 8.8 0.0 4.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3592) Glyco_hydro_3 PF00933.16 KUM58749.1 - 2.5e-58 197.4 0.0 3.5e-58 196.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.19 KUM58749.1 - 0.00026 20.9 0.0 0.0012 18.8 0.0 2.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.17 KUM58749.1 - 0.0024 17.4 0.0 0.0054 16.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_6 PF13480.1 KUM58749.1 - 0.026 14.4 0.0 0.19 11.6 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain NDT80_PhoG PF05224.7 KUM58750.1 - 3.1e-41 141.4 0.0 7.2e-41 140.2 0.0 1.6 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Aldedh PF00171.17 KUM58751.1 - 6.3e-156 519.3 0.3 7.8e-156 519.0 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glucosamine_iso PF01182.15 KUM58752.1 - 8.5e-23 81.1 0.0 1.2e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DPM3 PF08285.6 KUM58753.1 - 8.6e-25 86.4 1.6 1e-23 82.9 0.2 2.0 2 0 0 2 2 2 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF1469 PF07332.6 KUM58753.1 - 3.5 7.3 5.8 2.5 7.8 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1469) UQ_con PF00179.21 KUM58755.1 - 5e-25 87.5 0.1 7.1e-25 87.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Bac_surface_Ag PF01103.18 KUM58756.1 - 1.5e-38 133.1 0.3 1.9e-38 132.7 0.2 1.1 1 0 0 1 1 1 1 Surface antigen Cyto_heme_lyase PF01265.12 KUM58757.1 - 1.6e-78 263.8 0.2 1.9e-78 263.6 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Fungal_trans_2 PF11951.3 KUM58758.1 - 2.9e-12 45.8 0.2 5.3e-12 45.0 0.1 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain ABC1 PF03109.11 KUM58760.1 - 1.7e-23 82.8 0.1 5.1e-14 52.2 0.0 2.5 1 1 1 2 2 2 2 ABC1 family RIO1 PF01163.17 KUM58760.1 - 0.038 13.3 0.0 2 7.7 0.0 2.3 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.6 KUM58760.1 - 0.16 10.7 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase adh_short PF00106.20 KUM58761.1 - 4.1e-07 30.0 0.1 4.7e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM58761.1 - 0.00045 19.9 0.0 0.00056 19.6 0.0 1.1 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 KUM58761.1 - 0.052 12.7 0.1 0.062 12.5 0.0 1.1 1 0 0 1 1 1 0 NmrA-like family DUF383 PF04063.9 KUM58762.1 - 0.21 11.1 1.9 2.8 7.4 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF383) EAP30 PF04157.11 KUM58763.1 - 2.6e-39 134.6 0.0 3.4e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family MarR_2 PF12802.2 KUM58763.1 - 0.0016 18.0 0.1 0.0097 15.5 0.0 2.2 3 0 0 3 3 3 1 MarR family Ribosomal_L30_N PF08079.7 KUM58764.1 - 3.1e-24 84.7 12.7 5.2e-24 84.0 8.8 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 KUM58764.1 - 2.3e-17 62.2 1.7 6.3e-17 60.9 1.2 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Pribosyltran PF00156.22 KUM58765.1 - 1.6e-07 31.0 0.2 5.7e-07 29.2 0.2 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Acyl-CoA_dh_2 PF08028.6 KUM58766.1 - 1.2e-17 64.4 0.3 2.1e-17 63.6 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KUM58766.1 - 6e-07 30.0 0.0 9.9e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 KUM58766.1 - 0.00013 22.1 1.1 0.00076 19.5 0.1 2.3 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain IBR PF01485.16 KUM58767.1 - 0.00015 21.5 5.4 0.00015 21.5 3.7 4.5 4 1 0 4 4 4 2 IBR domain PRK PF00485.13 KUM58768.1 - 0.0017 17.9 0.0 0.0031 17.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family KAP_NTPase PF07693.9 KUM58768.1 - 0.017 14.1 0.0 0.024 13.6 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain AAA_17 PF13207.1 KUM58768.1 - 0.022 15.5 0.1 0.14 12.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KUM58768.1 - 0.033 14.5 0.0 0.14 12.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KUM58768.1 - 0.034 13.2 0.0 0.063 12.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.17 KUM58768.1 - 0.045 13.1 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ArgK PF03308.11 KUM58768.1 - 0.075 11.7 0.0 0.24 10.1 0.0 1.7 2 0 0 2 2 2 0 ArgK protein AAA_16 PF13191.1 KUM58768.1 - 0.079 12.9 0.0 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain GSCFA PF08885.6 KUM58768.1 - 0.085 12.3 0.0 0.19 11.2 0.0 1.5 2 0 0 2 2 2 0 GSCFA family AAA_30 PF13604.1 KUM58768.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain adh_short PF00106.20 KUM58769.1 - 3.3e-59 199.5 9.1 5.2e-30 104.5 0.4 2.4 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KUM58769.1 - 9.6e-28 97.0 2.8 4.1e-13 49.3 0.1 2.4 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 KUM58769.1 - 6.8e-17 60.9 0.3 2.5e-07 30.1 0.0 2.6 1 1 1 2 2 2 2 MaoC like domain Epimerase PF01370.16 KUM58769.1 - 0.00077 18.9 3.0 0.36 10.2 0.0 2.8 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 KUM58769.1 - 0.0022 17.1 0.3 0.0022 17.1 0.2 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_N PF00056.18 KUM58769.1 - 0.011 15.5 1.1 2.4 7.9 0.8 2.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain F-box-like PF12937.2 KUM58770.1 - 0.0095 15.6 0.1 0.03 14.0 0.1 1.9 1 0 0 1 1 1 1 F-box-like UFD1 PF03152.9 KUM58771.1 - 7.6e-23 80.5 0.0 8e-19 67.4 0.0 2.9 2 1 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 zf-LYAR PF08790.6 KUM58771.1 - 0.045 13.4 1.4 1.7 8.3 0.0 2.6 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger UBA PF00627.26 KUM58771.1 - 0.064 13.1 0.6 0.37 10.6 0.3 2.4 2 0 0 2 2 2 0 UBA/TS-N domain PRP21_like_P PF12230.3 KUM58771.1 - 0.12 11.8 1.9 9.3 5.6 0.1 3.1 3 0 0 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein zinc_ribbon_5 PF13719.1 KUM58771.1 - 0.26 10.8 5.7 9.5 5.8 0.2 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KUM58771.1 - 0.3 10.8 5.7 8.5 6.1 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 KUM58771.1 - 3.6 7.6 9.1 2.2 8.3 0.2 4.0 4 0 0 4 4 4 0 Zinc ribbon domain Yip1 PF04893.12 KUM58772.1 - 2.5e-07 30.3 17.1 5.4e-06 26.0 6.5 2.4 2 1 0 2 2 2 2 Yip1 domain Hpt PF01627.18 KUM58773.1 - 8.1e-10 38.5 0.0 1.4e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Hpt domain NusB PF01029.13 KUM58773.1 - 0.018 15.0 0.2 0.018 15.0 0.1 2.4 2 1 0 2 2 2 0 NusB family Fmp27 PF10344.4 KUM58773.1 - 0.25 8.9 6.8 0.31 8.6 4.7 1.2 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 DUF4481 PF14800.1 KUM58773.1 - 0.41 9.5 1.2 0.43 9.4 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) RNase_H2-Ydr279 PF09468.5 KUM58773.1 - 0.9 8.6 12.6 1.5 7.9 8.7 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Sigma70_ner PF04546.8 KUM58773.1 - 3.1 7.3 19.2 3.9 7.0 8.2 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region CPSF73-100_C PF11718.3 KUM58773.1 - 5.2 6.3 7.8 1.2 8.4 3.2 1.6 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term CDC45 PF02724.9 KUM58773.1 - 6.1 4.7 11.3 9 4.1 7.8 1.3 1 0 0 1 1 1 0 CDC45-like protein B12D PF06522.6 KUM58774.1 - 0.14 11.8 0.2 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit MFS_1 PF07690.11 KUM58775.1 - 6.9e-26 90.7 46.2 6.9e-26 90.7 32.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM58775.1 - 1.1e-07 30.8 13.2 1.1e-07 30.8 9.1 2.4 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KUM58775.1 - 0.00015 20.1 5.6 0.00015 20.1 3.9 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) LSM PF01423.17 KUM58777.1 - 7.1e-15 54.3 0.5 9.7e-15 53.8 0.4 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KUM58777.1 - 0.029 14.3 0.2 0.053 13.4 0.2 1.5 1 1 0 1 1 1 0 Ataxin 2 SM domain PGP_phosphatase PF09419.5 KUM58778.1 - 1.7e-60 203.2 0.0 2e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 KUM58778.1 - 0.0029 17.3 0.0 0.005 16.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KUM58778.1 - 0.01 16.2 0.2 3.1 8.1 0.0 2.1 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase LcrR PF09621.5 KUM58778.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Type III secretion system regulator (LcrR) DUF607 PF04678.8 KUM58779.1 - 5.6e-47 159.9 0.3 1.8e-46 158.3 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF607 Adaptin_binding PF10199.4 KUM58780.1 - 9.8e-20 71.2 0.7 2.5e-19 69.9 0.5 1.7 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 Tom22 PF04281.8 KUM58780.1 - 0.02 14.4 0.4 0.02 14.4 0.3 1.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 dsrm PF00035.20 KUM58783.1 - 2.9e-05 24.5 0.0 0.00021 21.8 0.0 2.1 2 0 0 2 2 2 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KUM58783.1 - 0.00011 22.3 0.0 0.00024 21.3 0.0 1.5 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 Prenyltrans PF00432.16 KUM58784.1 - 1.2e-43 146.3 28.7 4.4e-12 45.3 0.5 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KUM58784.1 - 1.9e-28 99.1 0.0 1.2e-17 64.3 0.0 4.2 2 1 2 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KUM58784.1 - 2.7e-05 24.1 0.0 0.0045 16.9 0.0 3.0 2 1 1 3 3 3 1 Prenyltransferase-like Pea-VEAacid PF08111.6 KUM58784.1 - 0.057 13.5 2.5 0.92 9.7 0.3 2.7 2 0 0 2 2 2 0 Pea-VEAacid family Zn_clus PF00172.13 KUM58785.1 - 0.0033 17.3 7.7 0.0063 16.3 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spectrin PF00435.16 KUM58785.1 - 0.19 12.0 0.0 0.51 10.6 0.0 1.7 1 0 0 1 1 1 0 Spectrin repeat PTPLA PF04387.9 KUM58787.1 - 4.4e-54 182.3 3.7 4.4e-54 182.3 2.6 1.5 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA DUF2823 PF11034.3 KUM58788.1 - 9.4e-31 105.7 13.3 1e-30 105.6 9.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) HSP9_HSP12 PF04119.7 KUM58788.1 - 0.42 10.7 5.9 1.4 9.0 3.8 1.9 1 1 1 2 2 2 0 Heat shock protein 9/12 DUF3176 PF11374.3 KUM58790.1 - 2.6e-33 114.1 1.3 6.1e-33 113.0 0.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) UBN2_3 PF14244.1 KUM58791.1 - 0.0038 16.8 0.0 0.008 15.7 0.0 1.5 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type Ank_2 PF12796.2 KUM58792.1 - 7e-63 208.9 3.0 7.1e-13 48.7 0.0 6.0 4 1 2 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KUM58792.1 - 4.1e-38 129.1 1.0 2.3e-06 27.9 0.0 9.0 5 3 4 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.25 KUM58792.1 - 1.3e-37 125.7 9.1 0.00049 19.7 0.0 11.9 12 0 0 12 12 12 9 Ankyrin repeat Ank_3 PF13606.1 KUM58792.1 - 1.4e-31 105.3 1.5 0.00027 20.8 0.0 11.3 11 0 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.1 KUM58792.1 - 1.4e-30 104.5 10.1 7.6e-07 29.1 0.0 9.3 5 5 5 10 10 10 8 Ankyrin repeats (many copies) FCD PF07729.7 KUM58792.1 - 0.035 14.4 0.7 29 4.9 0.1 3.6 2 1 1 3 3 3 0 FCD domain DUF3798 PF12683.2 KUM58792.1 - 0.25 10.3 0.0 2.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3798) DUF2324 PF10086.4 KUM58793.1 - 0.087 12.0 0.0 0.099 11.8 0.0 1.1 1 0 0 1 1 1 0 Putative membrane peptidase family (DUF2324) DUF3883 PF13020.1 KUM58794.1 - 0.02 14.6 0.0 0.052 13.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3883) Pyr_redox PF00070.22 KUM58795.1 - 2.1e-14 53.6 0.4 6.4e-11 42.5 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KUM58795.1 - 3.6e-14 53.0 0.3 2e-05 24.5 0.0 3.4 2 2 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KUM58795.1 - 7.1e-08 31.7 0.1 6.6e-06 25.2 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 KUM58795.1 - 2e-06 26.9 0.0 0.00081 18.4 0.0 2.6 2 1 1 3 3 3 2 Lycopene cyclase protein Trp_halogenase PF04820.9 KUM58795.1 - 2.4e-06 26.4 0.1 0.13 10.8 0.0 3.0 2 1 1 3 3 3 2 Tryptophan halogenase DAO PF01266.19 KUM58795.1 - 5.3e-06 25.5 0.1 0.12 11.3 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KUM58795.1 - 2.6e-05 24.3 0.0 0.0022 18.0 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM58795.1 - 4.1e-05 23.5 0.1 0.013 15.4 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KUM58795.1 - 0.00016 20.8 0.0 0.19 10.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain TrkA_N PF02254.13 KUM58795.1 - 0.002 18.1 0.1 2.6 8.0 0.0 2.4 2 0 0 2 2 2 2 TrkA-N domain Thi4 PF01946.12 KUM58795.1 - 0.0027 16.8 0.0 1.1 8.3 0.0 2.4 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.9 KUM58795.1 - 0.0047 15.4 0.1 0.37 9.2 0.0 2.9 2 1 1 3 3 3 1 HI0933-like protein NAD_binding_9 PF13454.1 KUM58795.1 - 0.01 15.6 0.0 32 4.2 0.1 3.9 3 1 1 4 4 4 0 FAD-NAD(P)-binding GIDA PF01134.17 KUM58795.1 - 0.026 13.3 0.2 1.1 8.0 0.0 3.3 4 0 0 4 4 4 0 Glucose inhibited division protein A Eno-Rase_NADH_b PF12242.3 KUM58795.1 - 0.076 12.8 0.9 0.42 10.4 0.1 2.5 2 1 1 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Semialdhyde_dh PF01118.19 KUM58795.1 - 0.14 12.4 0.7 5.6 7.3 0.0 3.0 2 2 1 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain MFS_1 PF07690.11 KUM58796.1 - 4e-29 101.4 82.7 6.8e-22 77.6 31.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KUM58796.1 - 0.013 15.2 10.7 0.015 15.0 0.6 3.3 3 0 0 3 3 3 0 MFS_1 like family CFEM PF05730.6 KUM58798.1 - 2.3e-15 56.1 7.8 3.4e-15 55.6 5.4 1.3 1 0 0 1 1 1 1 CFEM domain DUF3439 PF11921.3 KUM58798.1 - 1.6 8.5 10.6 0.29 10.8 4.6 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3439) Gly_transf_sug PF04488.10 KUM58799.1 - 3.3e-13 49.9 0.0 6.8e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Acyl_transf_3 PF01757.17 KUM58800.1 - 8.2e-44 149.8 33.6 1e-43 149.5 23.3 1.1 1 0 0 1 1 1 1 Acyltransferase family Rad52_Rad22 PF04098.10 KUM58803.1 - 1.2e-61 206.9 0.1 1.7e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Lipid_DES PF08557.5 KUM58804.1 - 2.2e-14 52.3 1.3 4.7e-14 51.3 0.9 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Aa_trans PF01490.13 KUM58806.1 - 1.1e-79 267.8 28.3 1.3e-79 267.6 19.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Asn_synthase PF00733.16 KUM58810.1 - 4.8e-68 229.3 0.0 6.6e-68 228.9 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KUM58810.1 - 1.9e-38 131.0 0.0 3.1e-38 130.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KUM58810.1 - 5.2e-30 104.1 0.0 1.3e-29 102.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KUM58810.1 - 1.2e-07 31.2 0.0 2.1e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 KUM58810.1 - 0.0007 18.3 0.0 0.047 12.3 0.0 2.6 1 1 2 3 3 3 1 Glutamine amidotransferases class-II NAD_synthase PF02540.12 KUM58810.1 - 0.0048 15.8 0.0 0.0096 14.8 0.0 1.4 1 0 0 1 1 1 1 NAD synthase UQ_con PF00179.21 KUM58811.1 - 2.8e-42 143.4 0.0 7.6e-31 106.4 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme UBA PF00627.26 KUM58812.1 - 3.9e-05 23.3 0.0 0.00011 21.8 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain UBX PF00789.15 KUM58812.1 - 0.0051 16.8 0.0 0.014 15.4 0.0 1.8 1 0 0 1 1 1 1 UBX domain zf-C2H2 PF00096.21 KUM58812.1 - 0.044 14.1 0.2 0.074 13.4 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type Crystallin PF00525.13 KUM58812.1 - 0.1 12.8 0.1 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Alpha crystallin A chain, N terminal Hydantoinase_B PF02538.9 KUM58812.1 - 0.1 10.7 4.1 0.14 10.3 2.8 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase Ndc1_Nup PF09531.5 KUM58812.1 - 2.4 6.5 7.1 3.1 6.1 5.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOBP PF15279.1 KUM58812.1 - 5.1 7.4 9.8 6.8 6.9 6.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Lipoprotein_X PF03305.8 KUM58812.1 - 5.8 6.2 12.2 12 5.1 8.5 1.6 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein Porin_3 PF01459.17 KUM58813.1 - 3.8e-68 229.7 4.2 4.3e-68 229.5 2.9 1.0 1 0 0 1 1 1 1 Eukaryotic porin DnaJ PF00226.26 KUM58814.1 - 3.9e-12 45.7 0.1 6.4e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Retinal PF15449.1 KUM58814.1 - 0.26 8.8 1.3 0.3 8.7 0.9 1.0 1 0 0 1 1 1 0 Retinal protein Gly-zipper_OmpA PF13436.1 KUM58814.1 - 5.9 6.5 9.0 11 5.6 6.2 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Ank_2 PF12796.2 KUM58815.1 - 1.5e-34 118.1 6.9 3.2e-10 40.2 0.3 4.1 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KUM58815.1 - 1.4e-21 75.0 6.3 0.00013 21.6 0.1 7.0 6 1 1 7 7 7 4 Ankyrin repeat Ank_3 PF13606.1 KUM58815.1 - 8.4e-19 65.7 4.7 0.055 13.7 0.0 7.8 6 1 1 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 KUM58815.1 - 3.3e-18 65.6 0.8 4e-05 24.0 0.0 5.6 4 3 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM58815.1 - 1.6e-17 63.0 7.7 2.7e-05 24.2 0.2 5.4 4 2 2 6 6 6 5 Ankyrin repeats (many copies) F-box PF00646.28 KUM58815.1 - 6.1e-07 28.9 0.1 2.3e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KUM58815.1 - 9.7e-07 28.4 0.0 2.2e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like Baculo_RING PF05883.6 KUM58815.1 - 0.084 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain FR47 PF08445.5 KUM58816.1 - 0.14 11.9 0.1 0.2 11.4 0.0 1.3 1 1 0 1 1 1 0 FR47-like protein Peptidase_M24 PF00557.19 KUM58817.1 - 4.1e-45 153.9 0.1 5.3e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF2924 PF11149.3 KUM58817.1 - 0.15 12.0 0.2 0.15 12.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2924) FA_desaturase PF00487.19 KUM58818.1 - 5.6e-27 94.8 13.0 8.1e-27 94.2 9.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Motile_Sperm PF00635.21 KUM58819.1 - 4.5e-26 90.6 0.2 8.9e-26 89.6 0.2 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF3813 PF12758.2 KUM58819.1 - 0.023 14.8 0.8 0.051 13.7 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) Phage_GP20 PF06810.6 KUM58819.1 - 0.026 13.9 0.2 0.042 13.2 0.1 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF756 PF05506.7 KUM58819.1 - 0.12 12.8 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF756) CPSase_L_D2 PF02786.12 KUM58820.1 - 1.3e-106 354.5 0.0 1.7e-84 282.3 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 KUM58820.1 - 6.4e-42 142.2 0.0 1.5e-41 141.0 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 KUM58820.1 - 1.5e-37 129.1 0.3 1.4e-20 73.7 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain CPSase_L_chain PF00289.17 KUM58820.1 - 2.6e-37 127.2 0.0 1.2e-17 63.9 0.0 2.9 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 KUM58820.1 - 1.1e-22 80.2 0.0 2.6e-07 29.7 0.0 4.1 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KUM58820.1 - 2.2e-17 62.9 0.0 6.3e-08 32.1 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KUM58820.1 - 1.4e-16 60.5 0.1 1.3e-07 31.2 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 KUM58820.1 - 2.3e-07 30.4 0.0 0.014 14.9 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.1 KUM58820.1 - 0.0009 18.5 0.0 0.12 11.5 0.0 2.6 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 KUM58820.1 - 0.0016 18.0 0.1 1 8.9 0.0 2.6 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain SET PF00856.23 KUM58822.1 - 2.2e-15 57.3 0.1 6.8e-14 52.4 0.1 2.8 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.13 KUM58822.1 - 1.7e-09 37.4 10.3 1.7e-09 37.4 7.2 1.8 2 0 0 2 2 2 1 MYND finger HTH_35 PF13693.1 KUM58822.1 - 0.054 13.2 0.0 3.3 7.5 0.0 3.0 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding AAA PF00004.24 KUM58824.1 - 3.4e-54 182.5 0.0 2.4e-43 147.4 0.0 3.0 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 KUM58824.1 - 1.7e-29 101.6 0.2 3.7e-29 100.5 0.1 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 KUM58824.1 - 1.5e-09 38.0 6.9 9.3e-06 25.7 0.1 4.3 4 1 1 5 5 4 2 AAA ATPase domain AAA_19 PF13245.1 KUM58824.1 - 1.3e-06 28.0 0.1 0.0035 17.0 0.0 3.6 3 0 0 3 3 3 1 Part of AAA domain AAA_2 PF07724.9 KUM58824.1 - 1.7e-06 28.0 0.0 0.08 12.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 KUM58824.1 - 1.1e-05 26.2 0.0 0.26 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KUM58824.1 - 1.5e-05 24.5 0.2 0.03 13.7 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.7 KUM58824.1 - 1.5e-05 24.6 0.3 0.11 12.1 0.0 3.4 3 0 0 3 3 3 2 NACHT domain Zeta_toxin PF06414.7 KUM58824.1 - 2.8e-05 23.3 0.0 0.14 11.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin RuvB_N PF05496.7 KUM58824.1 - 3.6e-05 22.9 0.0 0.0073 15.3 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KUM58824.1 - 4.3e-05 23.6 0.2 0.37 10.9 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KUM58824.1 - 8e-05 22.9 0.6 0.065 13.5 0.2 3.1 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KUM58824.1 - 0.00022 21.1 0.0 0.32 10.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KUM58824.1 - 0.00033 20.3 0.1 0.9 9.2 0.0 3.3 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) UPF0079 PF02367.12 KUM58824.1 - 0.00076 19.1 0.1 0.018 14.6 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 KUM58824.1 - 0.0017 18.3 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KUM58824.1 - 0.0029 17.0 2.1 3.6 6.9 0.1 3.5 2 2 1 3 3 3 1 AAA domain TIP49 PF06068.8 KUM58824.1 - 0.0048 15.6 0.0 1 8.0 0.0 2.4 2 0 0 2 2 2 1 TIP49 C-terminus AAA_33 PF13671.1 KUM58824.1 - 0.0057 16.5 0.1 0.22 11.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KUM58824.1 - 0.01 15.0 0.2 0.17 11.0 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KUM58824.1 - 0.016 15.4 0.0 7.1 6.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.10 KUM58824.1 - 0.03 14.0 0.0 0.54 9.9 0.0 2.3 2 0 0 2 2 2 0 NTPase ABC_tran PF00005.22 KUM58824.1 - 0.031 14.5 0.0 13 6.1 0.0 2.6 2 0 0 2 2 2 0 ABC transporter SKI PF01202.17 KUM58824.1 - 0.066 13.0 0.0 5 6.9 0.0 2.8 3 0 0 3 3 2 0 Shikimate kinase cobW PF02492.14 KUM58824.1 - 0.12 11.7 1.2 4.9 6.5 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.13 KUM58824.1 - 0.12 11.8 0.0 0.39 10.2 0.0 1.9 2 0 0 2 2 1 0 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.21 KUM58824.1 - 0.13 11.7 0.0 5.7 6.3 0.0 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain KaiC PF06745.8 KUM58824.1 - 0.14 11.2 0.1 9.1 5.3 0.0 2.3 2 0 0 2 2 2 0 KaiC DUF815 PF05673.8 KUM58824.1 - 0.14 11.0 0.0 2.4 7.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Cytidylate_kin2 PF13189.1 KUM58824.1 - 0.23 11.3 0.0 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family MCM PF00493.18 KUM58825.1 - 8.2e-135 448.8 0.1 9.1e-134 445.4 0.0 2.0 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 KUM58825.1 - 1.4e-27 96.5 0.2 4.3e-27 95.0 0.0 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KUM58825.1 - 2.2e-07 30.2 0.0 1.6e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KUM58825.1 - 1.1e-06 28.4 0.0 2.6e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KUM58825.1 - 0.021 14.4 0.0 0.077 12.5 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 KUM58825.1 - 0.091 13.1 0.3 0.58 10.5 0.2 2.4 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KUM58825.1 - 0.11 12.0 0.0 0.93 8.9 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain EGF_CA PF07645.10 KUM58826.1 - 2.9e-05 23.9 7.7 2.9e-05 23.9 5.4 2.3 2 1 0 2 2 2 1 Calcium-binding EGF domain EGF_3 PF12947.2 KUM58826.1 - 0.00013 21.8 6.4 0.00013 21.8 4.4 2.4 2 1 0 2 2 2 1 EGF domain FXa_inhibition PF14670.1 KUM58826.1 - 0.00064 19.7 1.9 0.00064 19.7 1.3 2.7 3 0 0 3 3 3 1 Coagulation Factor Xa inhibitory site cEGF PF12662.2 KUM58826.1 - 0.0046 16.5 3.2 0.0046 16.5 2.2 2.6 2 1 0 2 2 2 1 Complement Clr-like EGF-like Carb_kinase PF01256.12 KUM58827.1 - 1.1e-35 123.1 1.2 2.5e-34 118.6 0.8 2.1 1 1 0 1 1 1 1 Carbohydrate kinase SSI PF00720.12 KUM58827.1 - 0.13 12.1 0.0 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 Subtilisin inhibitor-like Enolase_C PF00113.17 KUM58829.1 - 4.2e-99 331.2 0.0 2.8e-53 180.8 0.0 2.1 2 0 0 2 2 2 2 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KUM58829.1 - 1.4e-48 164.1 0.1 2.9e-48 163.1 0.1 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain Cytadhesin_P30 PF07271.6 KUM58829.1 - 0.00091 18.5 0.9 0.0015 17.8 0.7 1.2 1 0 0 1 1 1 1 Cytadhesin P30/P32 MR_MLE_C PF13378.1 KUM58829.1 - 0.053 13.5 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Enolase C-terminal domain-like DUF706 PF05153.10 KUM58830.1 - 2e-127 423.7 3.4 2.7e-127 423.3 2.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 KUM58830.1 - 0.24 11.4 3.6 0.44 10.5 0.0 2.8 3 1 0 3 3 3 0 HD domain GFO_IDH_MocA PF01408.17 KUM58831.1 - 9.2e-23 81.0 0.2 1.7e-22 80.1 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KUM58831.1 - 1.9e-05 24.4 0.0 3.6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_2 PF03446.10 KUM58831.1 - 0.032 14.0 0.0 0.11 12.3 0.0 1.9 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase AMP-binding PF00501.23 KUM58832.1 - 7.3e-92 307.9 0.0 8.6e-92 307.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KUM58832.1 - 2.2e-10 41.3 0.0 5.6e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ribosomal_S19 PF00203.16 KUM58833.1 - 2.1e-33 113.7 0.3 3.4e-33 113.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 DUF3386 PF11866.3 KUM58833.1 - 0.082 12.0 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3386) Glyco_hydro_28 PF00295.12 KUM58834.1 - 5.9e-112 373.8 20.6 6.8e-112 373.6 14.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 NAD_binding_10 PF13460.1 KUM58835.1 - 1e-15 58.2 0.1 2.4e-15 57.0 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KUM58835.1 - 1.1e-06 28.3 0.0 1.8e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KUM58835.1 - 0.013 15.4 1.9 0.038 13.9 0.3 2.5 2 1 0 2 2 2 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 KUM58835.1 - 0.065 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Ribosomal_60s PF00428.14 KUM58836.1 - 9.1e-27 93.2 10.4 1.2e-26 92.8 7.2 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3138 PF11336.3 KUM58836.1 - 0.22 9.6 1.0 0.24 9.5 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) SPT2 PF08243.6 KUM58837.1 - 0.00069 19.9 16.3 0.00069 19.9 11.3 2.1 2 1 1 3 3 3 1 SPT2 chromatin protein Thiolase_N PF00108.18 KUM58838.1 - 7e-65 218.6 0.3 1.1e-64 217.9 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KUM58838.1 - 3.2e-41 139.6 0.4 3.2e-41 139.6 0.3 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KUM58838.1 - 0.0043 16.5 0.3 0.012 15.0 0.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 KUM58838.1 - 0.056 13.4 0.1 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal WLM PF08325.5 KUM58841.1 - 7.6e-47 159.5 0.0 2.9e-46 157.6 0.0 1.8 2 0 0 2 2 2 1 WLM domain SprT-like PF10263.4 KUM58841.1 - 0.00013 21.6 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 SprT-like family DUF45 PF01863.12 KUM58841.1 - 0.00095 19.0 0.1 0.0021 17.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 Peptidase_MA_2 PF13485.1 KUM58841.1 - 0.064 13.3 0.1 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 Peptidase MA superfamily PB1 PF00564.19 KUM58841.1 - 0.1 12.2 0.0 0.32 10.6 0.0 1.8 2 0 0 2 2 2 0 PB1 domain ubiquitin PF00240.18 KUM58841.1 - 0.14 11.5 0.0 0.33 10.3 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family Fungal_trans PF04082.13 KUM58842.1 - 0.00043 19.2 0.0 0.00069 18.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain IBR PF01485.16 KUM58843.1 - 7.3e-10 38.5 17.0 1.4e-05 24.8 2.0 3.5 3 0 0 3 3 3 3 IBR domain zf-C3HC4 PF00097.20 KUM58843.1 - 0.001 18.6 1.9 0.001 18.6 1.3 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KUM58843.1 - 0.0019 17.9 5.6 0.0019 17.9 3.9 4.1 2 2 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 KUM58843.1 - 0.0034 17.0 5.9 0.0034 17.0 4.1 3.7 3 2 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KUM58843.1 - 0.005 16.8 5.9 0.005 16.8 4.1 3.9 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KUM58843.1 - 0.082 12.5 11.4 5.5 6.6 0.1 3.9 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain Bac_rhamnosid PF05592.6 KUM58844.1 - 2.5e-129 431.7 0.0 3.2e-129 431.4 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 KUM58844.1 - 6.6e-51 172.2 0.8 1.2e-50 171.4 0.0 1.8 2 0 0 2 2 2 1 Alpha-L-rhamnosidase N-terminal domain DUF608 PF04685.8 KUM58844.1 - 0.011 14.4 0.0 0.02 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF608 Sugar_tr PF00083.19 KUM58845.1 - 3.7e-98 329.0 26.6 4.3e-98 328.8 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM58845.1 - 1.3e-26 93.1 38.6 3.1e-24 85.3 15.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Lysis_S PF04971.7 KUM58845.1 - 0.061 13.0 2.0 2.9 7.6 0.1 2.8 2 0 0 2 2 2 0 Lysis protein S RrnaAD PF00398.15 KUM58846.1 - 0.084 11.8 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase AA_permease_2 PF13520.1 KUM58848.1 - 2.4e-58 197.7 53.4 2.9e-58 197.4 37.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM58848.1 - 7.7e-35 120.1 48.6 1e-34 119.7 33.7 1.0 1 0 0 1 1 1 1 Amino acid permease ACBP PF00887.14 KUM58849.1 - 4.3e-27 93.6 0.0 8.3e-27 92.6 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Atg14 PF10186.4 KUM58849.1 - 0.29 10.0 0.0 0.29 10.0 0.0 2.1 3 0 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Daxx PF03344.10 KUM58849.1 - 2 6.7 16.7 3.6 5.9 11.6 1.3 1 0 0 1 1 1 0 Daxx Family Peptidase_S64 PF08192.6 KUM58849.1 - 2.3 6.4 4.8 3.4 5.8 3.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 Nop14 PF04147.7 KUM58849.1 - 2.3 6.0 16.1 3.1 5.5 11.2 1.1 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.6 KUM58849.1 - 8.1 4.1 7.4 11 3.7 5.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DASH_Ask1 PF08655.5 KUM58851.1 - 2.2e-32 110.6 0.1 5.1e-32 109.5 0.1 1.7 1 0 0 1 1 1 1 DASH complex subunit Ask1 HIG_1_N PF04588.8 KUM58852.1 - 6.8e-07 28.9 0.5 6.8e-07 28.9 0.4 1.7 2 0 0 2 2 2 1 Hypoxia induced protein conserved region Med26 PF08711.6 KUM58853.1 - 4.5e-13 48.4 0.3 8.6e-13 47.5 0.2 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Nup54 PF13874.1 KUM58854.1 - 4.4e-44 149.5 1.2 2.7e-43 147.0 0.0 2.3 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 KUM58854.1 - 6.5e-06 26.3 45.5 6.5e-06 26.3 31.5 2.5 1 1 1 2 2 2 2 Nucleoporin FG repeat region Fib_alpha PF08702.5 KUM58854.1 - 0.0089 16.1 1.1 0.02 14.9 0.8 1.6 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family EzrA PF06160.7 KUM58854.1 - 0.0099 14.1 5.5 0.033 12.3 2.4 2.0 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA ApoLp-III PF07464.6 KUM58854.1 - 0.011 15.8 1.5 0.023 14.7 1.0 1.6 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) V-SNARE_C PF12352.3 KUM58854.1 - 0.061 13.4 1.5 7.5 6.7 0.1 2.6 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus DUF948 PF06103.6 KUM58854.1 - 0.073 12.9 0.4 0.47 10.3 0.3 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF745 PF05335.8 KUM58854.1 - 0.13 11.7 2.5 0.25 10.8 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF3867 PF12983.2 KUM58854.1 - 0.15 11.9 2.8 2 8.3 1.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3867) DUF1664 PF07889.7 KUM58854.1 - 1.2 8.9 4.4 3.3 7.5 2.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.1 KUM58854.1 - 1.7 9.0 5.9 28 5.1 0.1 3.2 2 1 1 3 3 3 0 Snapin/Pallidin Tup_N PF08581.5 KUM58854.1 - 2.9 8.1 8.5 0.28 11.4 1.6 2.3 3 0 0 3 3 3 0 Tup N-terminal CHCH PF06747.8 KUM58855.1 - 1.5e-05 24.7 4.1 1.5e-05 24.7 2.9 2.6 3 0 0 3 3 3 2 CHCH domain Pet191_N PF10203.4 KUM58855.1 - 0.016 15.2 9.3 0.47 10.5 4.9 2.7 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 KUM58855.1 - 1.1 9.0 12.5 1.7 8.4 2.0 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CD45 PF12567.3 KUM58855.1 - 3.8 7.4 6.2 10 6.0 4.3 1.8 1 1 0 1 1 1 0 Leukocyte receptor CD45 COX6B PF02297.12 KUM58855.1 - 4.3 7.4 10.8 6.8 6.7 2.5 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Glyco_hydro_71 PF03659.9 KUM58856.1 - 3.7e-150 499.7 2.9 3.7e-150 499.7 2.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 Pkinase PF00069.20 KUM58858.1 - 3.8e-70 236.0 0.0 4.6e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM58858.1 - 3.9e-34 117.8 0.0 6.1e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KUM58858.1 - 4.6e-06 25.8 0.0 5.5e-05 22.3 0.0 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KUM58858.1 - 0.00036 19.5 0.0 0.00062 18.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KUM58858.1 - 0.0029 16.9 0.1 0.0049 16.2 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KUM58858.1 - 0.034 13.8 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family NCD1 PF04904.8 KUM58858.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) SNF5 PF04855.7 KUM58860.1 - 6.7e-84 281.1 0.0 9.3e-84 280.7 0.0 1.2 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 KUM58860.1 - 1.2e-05 24.5 1.1 3.1e-05 23.2 0.7 1.8 1 0 0 1 1 1 1 GATA zinc finger Abhydrolase_2 PF02230.11 KUM58861.1 - 6.4e-26 91.1 0.0 1.6e-18 66.9 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KUM58861.1 - 1e-05 25.5 0.1 2.2e-05 24.4 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM58861.1 - 0.00014 21.6 0.0 0.00024 20.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KUM58861.1 - 0.00026 20.5 0.0 0.00063 19.2 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) NACHT PF05729.7 KUM58863.1 - 6.5e-11 42.1 0.1 1.2e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain zf-H2C2_2 PF13465.1 KUM58863.1 - 1.8e-09 37.4 18.9 1.4e-05 25.1 0.3 5.5 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KUM58863.1 - 8.7e-08 31.9 27.1 0.0057 16.9 2.1 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.21 KUM58863.1 - 0.00024 21.2 32.8 0.00094 19.3 2.4 4.6 4 0 0 4 4 4 2 Zinc finger, C2H2 type AAA_16 PF13191.1 KUM58863.1 - 0.0003 20.8 0.2 0.0032 17.4 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KUM58863.1 - 0.0012 19.0 0.0 0.0029 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain zf-Di19 PF05605.7 KUM58863.1 - 0.0041 17.2 5.0 0.096 12.8 3.1 2.5 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 KUM58863.1 - 0.016 15.3 10.7 0.15 12.3 1.7 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type AAA PF00004.24 KUM58863.1 - 0.028 14.6 0.0 0.089 12.9 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-C2H2_jaz PF12171.3 KUM58863.1 - 0.035 14.2 18.0 0.33 11.1 0.8 3.9 4 0 0 4 4 3 0 Zinc-finger double-stranded RNA-binding AAA_19 PF13245.1 KUM58863.1 - 0.074 12.8 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 KUM58863.1 - 0.1 12.5 0.0 0.84 9.5 0.0 2.3 1 1 0 1 1 1 0 AAA domain zf-BED PF02892.10 KUM58863.1 - 0.88 9.3 12.0 0.52 10.1 0.2 3.5 3 0 0 3 3 3 0 BED zinc finger Zn_Tnp_IS1595 PF12760.2 KUM58863.1 - 1.7 8.5 8.4 0.15 11.8 0.9 2.7 2 0 0 2 2 2 0 Transposase zinc-ribbon domain XFP_N PF09364.5 KUM58864.1 - 9.4e-181 600.4 0.0 1.2e-180 600.0 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 KUM58864.1 - 2.4e-87 291.5 0.0 3.7e-87 291.0 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 KUM58864.1 - 3.1e-83 277.7 0.0 5.8e-83 276.8 0.0 1.5 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase DUF3632 PF12311.3 KUM58866.1 - 1.6e-17 63.9 6.1 5.5e-17 62.1 3.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) XFP_N PF09364.5 KUM58867.1 - 1.1e-16 60.4 0.0 1.6e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain Peptidase_M49 PF03571.10 KUM58868.1 - 2.7e-232 771.7 0.0 3.3e-232 771.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 bZIP_1 PF00170.16 KUM58869.1 - 0.025 14.5 2.2 0.036 14.0 1.5 1.2 1 0 0 1 1 1 0 bZIP transcription factor Ste5 PF11610.3 KUM58870.1 - 2.8 7.5 5.9 14 5.2 1.6 3.1 2 1 0 2 2 2 0 Scaffold protein Ste5-Fus5 binding region Pkinase PF00069.20 KUM58871.1 - 1.8e-17 63.3 0.0 4.3e-17 62.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM58871.1 - 3e-09 36.3 0.0 1.2e-08 34.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Aminotran_4 PF01063.14 KUM58872.1 - 5.6e-30 104.5 0.0 7.8e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Bap31 PF05529.7 KUM58874.1 - 0.6 9.5 5.0 0.62 9.4 3.5 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF3810 PF12725.2 KUM58874.1 - 1.7 7.4 4.3 2.1 7.1 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) TACC PF05010.9 KUM58875.1 - 6.8e-06 25.9 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) Macoilin PF09726.4 KUM58875.1 - 0.064 11.5 1.0 0.11 10.7 0.7 1.3 1 0 0 1 1 1 0 Transmembrane protein TFIIIC_delta PF12657.2 KUM58875.1 - 0.41 10.3 5.4 2.1 8.0 0.5 3.1 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term RRM_1 PF00076.17 KUM58876.1 - 0.00036 20.1 0.0 0.00058 19.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_POL_M_15KD PF02150.11 KUM58879.1 - 1.7e-10 40.3 1.4 1.7e-10 40.3 1.0 2.6 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit FYVE PF01363.16 KUM58879.1 - 0.041 13.7 3.4 1.8 8.5 0.7 2.3 2 0 0 2 2 2 0 FYVE zinc finger GFA PF04828.9 KUM58879.1 - 0.086 12.7 7.1 0.39 10.7 0.0 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme C1_1 PF00130.17 KUM58879.1 - 0.72 9.6 8.7 2.1 8.1 0.5 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rotamase PF00639.16 KUM58880.1 - 3.2e-23 82.2 0.1 4.2e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 KUM58880.1 - 1.4e-14 54.3 0.0 1.6e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 KUM58880.1 - 9.8e-10 38.1 2.2 9.8e-10 38.1 1.5 1.6 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.1 KUM58880.1 - 2.2e-05 25.0 0.0 3.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain MAM PF00629.18 KUM58880.1 - 0.098 12.4 0.1 0.19 11.5 0.0 1.5 1 1 0 1 1 1 0 MAM domain SET PF00856.23 KUM58881.1 - 9.5e-11 42.2 0.0 1.8e-08 34.8 0.0 2.7 2 0 0 2 2 2 2 SET domain HypA PF01155.14 KUM58881.1 - 0.32 10.7 2.1 0.38 10.4 0.1 2.0 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Med3 PF11593.3 KUM58881.1 - 1.5 7.9 9.4 5.8 6.0 2.8 2.2 1 1 1 2 2 2 0 Mediator complex subunit 3 fungal Ribosomal_L14 PF00238.14 KUM58882.1 - 8.3e-45 151.4 1.6 9.3e-45 151.3 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e FlgH PF02107.11 KUM58882.1 - 0.077 12.5 0.1 0.09 12.3 0.0 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein DEAD PF00270.24 KUM58883.1 - 8.2e-30 103.5 0.0 1.6e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM58883.1 - 1.6e-15 56.6 0.0 3.7e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KUM58883.1 - 0.00026 20.8 0.0 0.00051 19.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KUM58883.1 - 0.029 13.1 0.0 0.06 12.1 0.0 1.5 1 0 0 1 1 1 0 SNF2 family N-terminal domain COesterase PF00135.23 KUM58884.1 - 2.2e-78 264.3 0.3 2.7e-78 264.0 0.2 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KUM58884.1 - 2e-05 24.2 0.3 0.00018 21.1 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KUM58884.1 - 0.012 14.8 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family SNO PF01174.14 KUM58885.1 - 1e-54 185.0 0.0 1.1e-44 152.3 0.0 2.1 1 1 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 KUM58885.1 - 2.2e-09 37.1 0.0 1.9e-07 30.8 0.0 2.2 2 0 0 2 2 2 2 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 KUM58885.1 - 0.00034 20.1 0.0 0.002 17.5 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 KUM58885.1 - 0.0011 18.4 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 KUM58885.1 - 0.016 14.4 0.0 0.036 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative amidotransferase RRM_5 PF13893.1 KUM58886.1 - 0.00026 20.7 0.0 0.00039 20.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KUM58886.1 - 0.00054 19.5 0.0 0.00077 19.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM58886.1 - 0.0057 16.6 0.0 0.0084 16.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ACPS PF01648.15 KUM58887.1 - 2.6e-09 36.9 0.0 7.1e-09 35.5 0.0 1.8 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Anillin PF08174.6 KUM58888.1 - 1.1e-28 100.0 0.4 4.3e-28 98.1 0.3 2.0 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 KUM58888.1 - 5.1e-07 29.8 0.0 1.9e-06 28.0 0.0 2.0 1 0 0 1 1 1 1 PH domain DUF829 PF05705.9 KUM58889.1 - 3.9e-58 196.9 0.1 4.5e-58 196.7 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 KUM58889.1 - 0.058 13.2 0.0 0.12 12.1 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Kelch_3 PF13415.1 KUM58891.1 - 3.4e-34 116.2 8.3 2.4e-07 30.7 0.0 6.3 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.1 KUM58891.1 - 6.3e-30 102.7 11.1 5e-12 45.3 0.0 6.4 5 2 1 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 KUM58891.1 - 1e-18 66.6 3.4 0.0033 17.5 0.1 6.5 4 2 2 6 6 6 5 Kelch motif Kelch_1 PF01344.20 KUM58891.1 - 1.7e-14 53.0 0.1 0.016 14.7 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.1 KUM58891.1 - 1.9e-12 46.8 2.6 0.013 15.4 0.0 6.3 6 1 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 KUM58891.1 - 4.8e-12 45.1 5.9 0.00041 19.9 0.0 6.4 6 1 0 6 6 6 3 Kelch motif Ank_2 PF12796.2 KUM58892.1 - 4.9e-132 430.6 8.6 4.3e-23 81.4 0.0 8.8 2 1 7 9 9 9 8 Ankyrin repeats (3 copies) Ank PF00023.25 KUM58892.1 - 8.1e-114 366.2 7.9 7.4e-09 34.9 0.0 15.7 16 0 0 16 16 16 14 Ankyrin repeat Ank_4 PF13637.1 KUM58892.1 - 1.6e-88 289.6 5.0 3.8e-11 43.1 0.0 12.8 5 2 10 15 15 15 13 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM58892.1 - 2e-82 262.8 7.0 4.8e-07 29.3 0.0 15.5 16 0 0 16 16 16 14 Ankyrin repeat Ank_5 PF13857.1 KUM58892.1 - 2.2e-74 243.7 9.1 5.7e-09 35.9 0.0 14.2 3 1 11 14 14 14 13 Ankyrin repeats (many copies) NACHT PF05729.7 KUM58892.1 - 9.8e-06 25.3 0.1 2.6e-05 23.9 0.1 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KUM58892.1 - 3.3e-05 23.9 0.2 0.00011 22.3 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain DUF4350 PF14258.1 KUM58892.1 - 0.00018 21.6 0.3 34 4.7 0.0 5.4 5 0 0 5 5 5 0 Domain of unknown function (DUF4350) HTH_22 PF13309.1 KUM58892.1 - 0.011 15.4 0.0 86 2.9 0.0 6.4 9 0 0 9 9 9 0 HTH domain ZZ PF00569.12 KUM58892.1 - 1.7 8.2 12.5 0.09 12.3 4.5 2.1 2 0 0 2 2 2 0 Zinc finger, ZZ type PNP_UDP_1 PF01048.15 KUM58893.1 - 8.2e-13 47.8 0.1 2.9e-12 46.0 0.1 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily DUF2284 PF10050.4 KUM58893.1 - 0.019 14.5 1.1 0.028 14.0 0.7 1.2 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) Transp_cyt_pur PF02133.10 KUM58895.1 - 2.9e-153 510.5 42.1 3.4e-153 510.3 29.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PI-PLC-X PF00388.14 KUM58896.1 - 8.8e-59 197.0 0.0 1.8e-58 196.0 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KUM58896.1 - 3e-40 136.8 0.1 2.6e-39 133.8 0.1 2.3 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KUM58896.1 - 1e-05 25.4 0.0 3e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_8 PF13833.1 KUM58896.1 - 0.0054 16.3 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KUM58896.1 - 0.013 14.7 0.1 0.054 12.8 0.1 2.1 2 0 0 2 2 2 0 EF hand GDPD PF03009.12 KUM58896.1 - 0.019 14.4 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family EF-hand_6 PF13405.1 KUM58896.1 - 0.093 12.6 3.1 0.13 12.2 0.2 2.7 3 0 0 3 3 3 0 EF-hand domain Ndufs5 PF10200.4 KUM58896.1 - 0.13 12.2 0.4 0.31 11.0 0.3 1.6 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa EF-hand_7 PF13499.1 KUM58896.1 - 0.13 12.4 0.1 0.4 10.8 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain pair CrtC PF07143.6 KUM58897.1 - 0.15 11.3 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Hydroxyneurosporene synthase (CrtC) DUF4131 PF13567.1 KUM58898.1 - 0.2 11.0 7.5 0.24 10.7 5.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Urb2 PF10441.4 KUM58899.1 - 1.3e-62 211.3 0.0 1.3e-62 211.3 0.0 3.4 4 0 0 4 4 4 1 Urb2/Npa2 family DUF3176 PF11374.3 KUM58900.1 - 3e-39 133.3 0.4 3e-39 133.3 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) DUF2786 PF10979.3 KUM58901.1 - 1.6e-12 46.9 0.4 3.7e-12 45.7 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2786) NmrA PF05368.8 KUM58902.1 - 2.4e-52 177.5 0.4 2.8e-52 177.2 0.3 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KUM58902.1 - 1.7e-13 51.0 0.3 2.5e-13 50.4 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KUM58902.1 - 1.6e-07 30.3 0.1 2.4e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KUM58902.1 - 0.00059 19.8 0.3 0.001 19.0 0.2 1.4 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.5 KUM58902.1 - 0.0079 15.8 0.1 0.014 15.0 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM58902.1 - 0.0081 15.6 0.1 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KUM58902.1 - 0.013 14.5 0.1 0.017 14.1 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KUM58902.1 - 0.033 14.4 0.4 0.074 13.3 0.1 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 KUM58902.1 - 0.051 13.4 0.5 0.091 12.6 0.3 1.5 1 0 0 1 1 1 0 short chain dehydrogenase DXP_reductoisom PF02670.11 KUM58902.1 - 0.07 13.6 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase A_deaminase PF00962.17 KUM58903.1 - 2.8e-16 59.3 0.0 3.5e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase RVT_1 PF00078.22 KUM58905.1 - 8.1e-07 28.6 0.1 2.9e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CENP-F_leu_zip PF10473.4 KUM58905.1 - 0.0093 15.8 0.4 0.12 12.2 0.0 2.6 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Snapin_Pallidin PF14712.1 KUM58905.1 - 0.031 14.5 0.2 4.1 7.7 0.0 3.3 3 0 0 3 3 3 0 Snapin/Pallidin U5_2-snRNA_bdg PF10597.4 KUM58905.1 - 0.11 12.1 0.0 0.3 10.6 0.0 1.7 1 0 0 1 1 1 0 U5-snRNA binding site 2 of PrP8 Pox_A_type_inc PF04508.7 KUM58905.1 - 4.5 7.3 6.7 16 5.6 0.1 3.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Aldedh PF00171.17 KUM58906.1 - 4.2e-145 483.6 0.0 5e-145 483.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KUM58906.1 - 0.017 13.8 0.0 0.062 12.0 0.0 1.8 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) zf-HC2 PF13490.1 KUM58908.1 - 0.78 9.7 4.3 2.6 8.0 1.0 2.5 2 0 0 2 2 2 0 Putative zinc-finger MFS_1 PF07690.11 KUM58909.1 - 1.1e-29 103.3 39.8 7.9e-29 100.4 25.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1049 PF06305.6 KUM58909.1 - 0.0029 17.0 0.6 0.011 15.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1049) Hexapep PF00132.19 KUM58910.1 - 1.2e-07 30.8 3.7 0.0057 16.1 1.3 3.2 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KUM58910.1 - 0.00032 20.7 0.0 0.00061 19.9 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain 2OG-FeII_Oxy PF03171.15 KUM58911.1 - 1e-14 54.6 0.0 1.9e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KUM58911.1 - 1.4e-12 48.1 0.0 4.2e-12 46.6 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal Epimerase PF01370.16 KUM58912.1 - 4e-18 65.7 0.0 6.6e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KUM58912.1 - 1e-10 40.8 0.0 1.3e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KUM58912.1 - 3.8e-08 32.5 0.1 5.4e-07 28.7 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KUM58912.1 - 4.1e-08 33.4 0.0 1.4e-07 31.6 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KUM58912.1 - 4.9e-06 25.6 0.0 8e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KUM58912.1 - 1.8e-05 24.7 0.0 3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM58912.1 - 0.0014 18.2 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 KUM58912.1 - 0.033 13.0 0.0 0.073 11.9 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain Glyco_hydro_114 PF03537.8 KUM58913.1 - 4e-28 97.0 0.5 8.3e-28 95.9 0.4 1.6 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Spt5_N PF11942.3 KUM58913.1 - 0.011 16.3 8.4 0.024 15.2 5.8 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal CENP-B_dimeris PF09026.5 KUM58913.1 - 0.055 13.7 6.2 0.12 12.6 4.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 KUM58913.1 - 0.062 12.8 7.6 0.099 12.1 5.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin Na_H_antiport_1 PF06965.7 KUM58913.1 - 0.2 10.4 0.0 0.31 9.7 0.0 1.3 1 0 0 1 1 1 0 Na+/H+ antiporter 1 BSP_II PF05432.6 KUM58913.1 - 0.29 10.3 16.0 0.55 9.4 11.1 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) PBP1_TM PF14812.1 KUM58913.1 - 0.31 11.3 5.4 0.64 10.3 3.8 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sporozoite_P67 PF05642.6 KUM58913.1 - 0.43 8.3 12.0 0.61 7.8 8.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.7 KUM58913.1 - 0.46 8.3 10.6 0.6 7.9 7.4 1.1 1 0 0 1 1 1 0 Nop14-like family MGC-24 PF05283.6 KUM58913.1 - 0.52 10.0 9.1 0.059 13.1 3.1 1.7 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) Daxx PF03344.10 KUM58913.1 - 0.61 8.4 12.5 0.87 7.9 8.7 1.1 1 0 0 1 1 1 0 Daxx Family Sigma70_ner PF04546.8 KUM58913.1 - 1.8 8.1 10.6 2.8 7.4 7.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Tim54 PF11711.3 KUM58913.1 - 2.2 6.7 5.7 3.3 6.1 4.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NOA36 PF06524.7 KUM58913.1 - 4.8 6.3 10.8 8 5.6 7.5 1.3 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.11 KUM58913.1 - 7.2 5.5 8.0 12 4.8 5.6 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Glyco_hydro_71 PF03659.9 KUM58914.1 - 4.7e-138 459.8 5.5 5.4e-138 459.6 3.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Omp28 PF11551.3 KUM58914.1 - 0.033 13.7 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Outer membrane protein Omp28 DUF3463 PF11946.3 KUM58914.1 - 0.13 11.8 0.4 0.34 10.5 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3463) PAPA-1 PF04795.7 KUM58915.1 - 2e-28 98.9 6.7 2e-28 98.9 4.6 3.2 4 0 0 4 4 4 1 PAPA-1-like conserved region Mus7 PF09462.5 KUM58916.1 - 9e-204 678.8 0.0 1.2e-203 678.3 0.0 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family WD40 PF00400.27 KUM58917.1 - 3.9e-19 67.7 15.7 0.0001 22.0 0.6 7.0 6 1 0 6 6 6 4 WD domain, G-beta repeat SRA1 PF07304.6 KUM58917.1 - 8.3e-15 54.8 0.0 8.3e-15 54.8 0.0 3.8 4 0 0 4 4 4 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 KUM58917.1 - 0.1 12.3 0.1 1 9.0 0.0 2.5 1 1 0 1 1 1 0 Sec23-binding domain of Sec16 Prp18 PF02840.10 KUM58917.1 - 0.17 11.6 0.9 0.47 10.2 0.1 2.1 2 1 0 2 2 2 0 Prp18 domain Pex14_N PF04695.8 KUM58918.1 - 6.3e-36 123.4 0.7 6.3e-36 123.4 0.5 2.5 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region B12D PF06522.6 KUM58919.1 - 0.00022 20.8 0.0 0.00042 19.9 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit RRM_1 PF00076.17 KUM58920.1 - 6e-17 61.0 0.0 9.1e-17 60.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM58920.1 - 9.7e-13 47.9 0.0 1.3e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM58920.1 - 8.6e-10 38.3 0.0 1.3e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KUM58920.1 - 0.046 13.4 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 Nup35_RRM_2 PF14605.1 KUM58920.1 - 0.091 12.5 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Mito_carr PF00153.22 KUM58923.1 - 3e-32 110.1 0.1 1.2e-17 63.3 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein TAF8_C PF10406.4 KUM58924.1 - 6.7e-20 70.8 0.0 1.8e-19 69.5 0.0 1.8 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 KUM58924.1 - 3.4e-09 36.2 0.0 6e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated PAP2 PF01569.16 KUM58924.1 - 0.046 13.4 0.1 0.091 12.4 0.0 1.5 1 0 0 1 1 1 0 PAP2 superfamily Mitochondr_Som1 PF11093.3 KUM58925.1 - 2.1e-12 46.6 0.1 2.9e-12 46.1 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Cadherin_pro PF08758.6 KUM58925.1 - 0.079 12.7 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 Cadherin prodomain like Rad51 PF08423.6 KUM58926.1 - 0.00012 21.0 0.1 0.0019 17.1 0.0 2.4 2 1 0 2 2 2 1 Rad51 PALP PF00291.20 KUM58927.1 - 1.3e-77 261.0 0.5 1.9e-77 260.4 0.4 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KUM58927.1 - 0.011 14.8 0.1 0.018 14.1 0.1 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family IlvN PF07991.7 KUM58928.1 - 4.4e-45 153.0 0.0 6.2e-45 152.5 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 KUM58928.1 - 1.2e-44 151.7 0.0 2e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 KUM58928.1 - 0.025 14.4 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Isochorismatase PF00857.15 KUM58929.1 - 1.3e-23 83.8 0.0 8.2e-23 81.2 0.0 2.1 1 1 0 1 1 1 1 Isochorismatase family 2OG-FeII_Oxy_2 PF13532.1 KUM58929.1 - 2.4e-23 82.9 0.0 4.2e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GST_C_3 PF14497.1 KUM58929.1 - 2e-05 24.9 0.0 8.3e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KUM58929.1 - 0.004 17.0 0.1 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KUM58929.1 - 0.03 14.3 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Lipase_GDSL PF00657.17 KUM58930.1 - 2.4e-14 53.7 0.1 2.9e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KUM58930.1 - 3.1e-12 46.9 1.2 3.9e-12 46.6 0.8 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF1330 PF07045.6 KUM58930.1 - 0.084 12.7 0.2 16 5.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1330) ECH PF00378.15 KUM58931.1 - 1.9e-33 115.5 0.1 2.9e-33 115.0 0.1 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family HSP20 PF00011.16 KUM58932.1 - 2.5e-18 65.8 0.1 1.2e-17 63.6 0.1 2.0 1 1 0 1 1 1 1 Hsp20/alpha crystallin family Tbf5 PF06331.7 KUM58933.1 - 7.1e-24 83.3 1.7 8.3e-24 83.1 1.2 1.1 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DUF1325 PF07039.6 KUM58933.1 - 0.079 12.5 0.5 0.087 12.4 0.3 1.2 1 0 0 1 1 1 0 SGF29 tudor-like domain UQ_con PF00179.21 KUM58934.1 - 6.7e-37 126.0 0.0 9.1e-37 125.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KUM58934.1 - 0.076 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Oxidored_FMN PF00724.15 KUM58935.1 - 1.3e-89 300.5 0.0 1.5e-89 300.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Fungal_trans PF04082.13 KUM58936.1 - 9.3e-26 90.2 0.3 1.7e-25 89.4 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SLAC1 PF03595.12 KUM58937.1 - 1.2e-57 195.0 34.6 1.4e-57 194.8 24.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel TMEM240 PF15207.1 KUM58937.1 - 0.49 9.9 2.0 1.1 8.7 0.1 2.1 2 0 0 2 2 2 0 TMEM240 family TPR_12 PF13424.1 KUM58938.1 - 1e-30 105.4 9.3 3.1e-11 43.0 0.0 5.3 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 KUM58938.1 - 2.3e-15 55.9 19.9 0.0042 16.9 0.1 7.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 KUM58938.1 - 5.5e-08 33.2 1.2 0.89 10.3 0.0 4.9 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KUM58938.1 - 3e-06 26.7 1.3 0.17 11.5 0.0 3.9 4 0 0 4 4 4 2 TPR repeat TPR_19 PF14559.1 KUM58938.1 - 3.4e-05 24.1 3.7 2 8.8 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 KUM58938.1 - 0.00017 21.6 0.6 0.18 11.9 0.1 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 KUM58938.1 - 0.0002 20.8 3.7 0.2 11.3 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KUM58938.1 - 0.00037 20.2 7.1 0.11 12.4 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KUM58938.1 - 0.0006 19.4 13.4 0.057 13.2 0.1 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 KUM58938.1 - 0.001 18.7 1.6 5.9 6.9 0.0 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KUM58938.1 - 0.0016 18.8 8.5 5.7 7.8 0.0 6.3 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_21 PF09976.4 KUM58938.1 - 0.0043 17.0 1.3 0.24 11.3 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.4 KUM58938.1 - 0.023 14.1 0.6 4.1 6.7 0.0 2.5 3 0 0 3 3 3 0 26S proteasome subunit RPN7 TPR_6 PF13174.1 KUM58938.1 - 1.1 9.8 10.9 4.6 7.9 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat 2OG-FeII_Oxy PF03171.15 KUM58939.1 - 1.3e-14 54.2 0.0 2.3e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KUM58939.1 - 8.6e-11 42.3 0.0 5.8e-09 36.4 0.0 2.3 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal Glyco_hydro_43 PF04616.9 KUM58940.1 - 7.5e-33 113.8 3.5 9.5e-33 113.5 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Fungal_trans PF04082.13 KUM58941.1 - 6.4e-15 54.7 0.2 1.3e-14 53.7 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Cu_amine_oxid PF01179.15 KUM58942.1 - 5.7e-147 489.7 0.3 3.9e-135 450.7 0.0 2.0 2 0 0 2 2 2 2 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KUM58942.1 - 5.8e-07 29.5 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KUM58942.1 - 0.0011 19.0 0.1 0.0027 17.7 0.1 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain AA_permease_2 PF13520.1 KUM58943.1 - 3.9e-64 216.7 49.4 4.7e-64 216.5 34.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM58943.1 - 1e-21 76.8 41.2 1.5e-21 76.2 28.6 1.2 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.3 KUM58944.1 - 6.7e-55 186.2 0.4 9e-55 185.8 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain T2SF PF00482.18 KUM58944.1 - 0.031 14.2 0.4 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F MPC PF03650.8 KUM58945.1 - 8.8e-44 148.2 0.3 1.1e-43 147.9 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) DUF2863 PF11062.3 KUM58945.1 - 0.098 10.7 0.2 0.68 7.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2863) Glyco_hydro_28 PF00295.12 KUM58946.1 - 7.7e-51 172.9 5.3 2.1e-50 171.5 3.6 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 KUM58946.1 - 0.87 9.3 17.6 0.95 9.1 10.3 2.3 2 1 0 2 2 2 0 Right handed beta helix region CBP4 PF07960.6 KUM58947.1 - 3.1e-33 114.1 2.2 3.4e-33 113.9 1.5 1.0 1 0 0 1 1 1 1 CBP4 IncA PF04156.9 KUM58947.1 - 0.007 15.9 0.2 0.0088 15.6 0.1 1.1 1 0 0 1 1 1 1 IncA protein G6PD_bact PF10786.4 KUM58947.1 - 0.037 13.4 3.9 0.041 13.3 2.7 1.1 1 0 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) Trp_oprn_chp PF09534.5 KUM58947.1 - 0.055 13.0 1.2 0.1 12.2 0.0 1.8 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) AAA_11 PF13086.1 KUM58947.1 - 0.14 11.7 2.0 0.15 11.6 1.4 1.0 1 0 0 1 1 1 0 AAA domain MMtag PF10159.4 KUM58947.1 - 2.5 8.1 9.0 1.2 9.2 4.7 1.5 1 1 1 2 2 2 0 Kinase phosphorylation protein Sel1 PF08238.7 KUM58949.1 - 9.9e-45 149.9 25.4 1.4e-07 31.9 0.0 7.5 7 0 0 7 7 7 7 Sel1 repeat TPR_20 PF14561.1 KUM58949.1 - 0.16 12.1 0.9 0.96 9.6 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Zn_clus PF00172.13 KUM58950.1 - 1e-07 31.7 8.8 1e-07 31.7 6.1 2.8 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.1 KUM58950.1 - 0.0004 20.5 4.0 0.0004 20.5 2.8 3.4 4 0 0 4 4 4 2 Zinc-finger double domain Fungal_trans PF04082.13 KUM58950.1 - 0.00059 18.7 0.0 0.00088 18.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KUM58950.1 - 0.0019 18.4 15.1 0.0035 17.5 3.1 3.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KUM58950.1 - 0.0065 16.7 4.0 0.0065 16.7 2.8 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 KUM58950.1 - 0.044 14.0 5.9 0.2 11.9 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Pkinase PF00069.20 KUM58953.1 - 8e-05 21.9 0.0 0.00069 18.8 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain APH PF01636.18 KUM58953.1 - 0.00036 20.3 0.1 0.00089 19.0 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KUM58953.1 - 0.0083 15.2 0.0 0.03 13.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase DUF204 PF02659.10 KUM58954.1 - 0.078 13.1 0.6 0.078 13.1 0.4 2.8 3 1 0 3 3 3 0 Domain of unknown function DUF GST_N_3 PF13417.1 KUM58955.1 - 2.6e-09 37.1 0.0 4.7e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KUM58955.1 - 9.4e-09 35.1 0.0 1.8e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KUM58955.1 - 2.7e-08 33.5 0.0 6.3e-08 32.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KUM58955.1 - 5.7e-08 32.6 0.0 7.7e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KUM58955.1 - 4.4e-06 26.7 0.0 8.4e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KUM58955.1 - 1.9e-05 25.0 0.0 3.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Y_phosphatase3C PF13348.1 KUM58955.1 - 0.038 14.1 0.0 0.16 12.0 0.0 2.1 2 0 0 2 2 2 0 Tyrosine phosphatase family C-terminal region Ctr PF04145.10 KUM58956.1 - 3.6e-36 124.3 0.1 4.5e-36 124.0 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family PAP2 PF01569.16 KUM58956.1 - 0.52 9.9 3.6 1.5 8.4 2.5 1.8 1 1 0 1 1 1 0 PAP2 superfamily FAD_binding_8 PF08022.7 KUM58957.1 - 7.8e-20 70.7 0.0 1.6e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KUM58957.1 - 7.7e-19 68.1 0.0 1.6e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KUM58957.1 - 1.4e-16 60.6 12.6 3.2e-16 59.5 8.7 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KUM58957.1 - 0.0004 20.4 0.0 0.0017 18.4 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KUM58957.1 - 0.19 12.3 0.0 13 6.4 0.0 2.6 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF1687 PF07955.6 KUM58958.1 - 1.1e-12 48.0 0.1 4.7e-12 46.0 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) Pkinase PF00069.20 KUM58959.1 - 2.7e-56 190.6 0.1 2.1e-55 187.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM58959.1 - 2.8e-28 98.7 0.1 8.7e-20 70.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 KUM58959.1 - 2.2e-06 28.0 0.2 6.1e-06 26.6 0.1 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KUM58959.1 - 0.00053 19.0 0.1 0.0068 15.4 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KUM58959.1 - 0.0015 18.3 2.7 0.34 10.5 0.0 3.5 3 1 1 4 4 4 2 Phosphotransferase enzyme family AATase PF07247.7 KUM58960.1 - 1.7e-22 79.6 0.0 3.3e-22 78.7 0.0 1.4 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 KUM58960.1 - 0.00029 19.7 0.0 0.0039 16.0 0.0 2.1 2 0 0 2 2 2 1 Condensation domain WES_acyltransf PF03007.11 KUM58960.1 - 0.005 16.4 0.0 0.0087 15.6 0.0 1.3 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain LigB PF02900.13 KUM58961.1 - 2.1e-45 154.8 0.0 1.8e-44 151.7 0.0 1.9 1 1 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase L51_S25_CI-B8 PF05047.11 KUM58962.1 - 5.9e-13 48.3 0.0 7.4e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Abhydrolase_2 PF02230.11 KUM58963.1 - 2.1e-55 187.5 0.0 2.4e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KUM58963.1 - 2.9e-14 53.0 0.0 3.9e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KUM58963.1 - 2.1e-09 37.6 0.0 1.8e-05 24.7 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KUM58963.1 - 1.2e-06 27.9 0.0 5.7e-05 22.4 0.0 2.4 3 0 0 3 3 3 1 Prolyl oligopeptidase family LIP PF03583.9 KUM58963.1 - 0.00012 21.3 0.0 0.005 16.0 0.0 2.1 2 0 0 2 2 2 1 Secretory lipase FSH1 PF03959.8 KUM58963.1 - 0.0013 18.2 0.0 0.0031 16.9 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydro_lipase PF04083.11 KUM58963.1 - 0.006 15.9 0.0 1 8.8 0.0 2.2 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region BAAT_C PF08840.6 KUM58963.1 - 0.0075 15.9 0.0 0.35 10.5 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 KUM58963.1 - 0.017 14.6 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 KUM58963.1 - 0.029 13.9 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF676 PF05057.9 KUM58963.1 - 0.052 12.8 0.0 7.4 5.7 0.0 2.2 2 0 0 2 2 2 0 Putative serine esterase (DUF676) AXE1 PF05448.7 KUM58963.1 - 0.054 11.9 0.0 0.08 11.4 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase PF00756.15 KUM58963.1 - 0.055 12.8 0.0 0.17 11.2 0.0 1.7 2 0 0 2 2 2 0 Putative esterase DUF1581 PF07619.6 KUM58963.1 - 0.1 12.6 0.1 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1581) DUF2974 PF11187.3 KUM58963.1 - 0.12 11.7 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Cutinase PF01083.17 KUM58963.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Cutinase Pyr_redox_2 PF07992.9 KUM58964.1 - 3.8e-13 49.7 0.0 5.7e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KUM58964.1 - 6.9e-05 22.9 0.9 2.8 7.9 0.0 3.2 1 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KUM58964.1 - 0.00073 18.5 0.0 0.014 14.3 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 KUM58964.1 - 0.0038 16.1 0.0 0.86 8.3 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.9 KUM58964.1 - 0.0044 15.5 0.0 0.014 13.8 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 KUM58964.1 - 0.015 15.0 0.1 3.6 7.3 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 KUM58964.1 - 0.099 11.7 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Thi4 family ubiquitin PF00240.18 KUM58966.1 - 2.1e-24 84.7 0.0 2.5e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KUM58966.1 - 4.2e-14 51.9 0.0 5.2e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KUM58966.1 - 0.0012 19.1 0.0 0.0039 17.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Pkinase PF00069.20 KUM58967.1 - 0.02 14.0 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain DUF3824 PF12868.2 KUM58969.1 - 1.5e-13 51.8 3.9 1.5e-13 51.8 2.7 7.8 3 2 3 7 7 7 1 Domain of unknwon function (DUF3824) DUF3681 PF12442.3 KUM58969.1 - 0.08 13.1 3.9 2.3 8.4 0.1 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3681) DUF2910 PF11139.3 KUM58969.1 - 2.4 7.2 11.7 47 3.0 6.0 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF2910) ABA_WDS PF02496.11 KUM58969.1 - 9.9 6.4 33.9 1.1 9.4 1.0 5.6 5 1 0 5 5 5 0 ABA/WDS induced protein Phosphoesterase PF04185.9 KUM58970.1 - 2.8e-69 234.1 0.7 4.9e-69 233.3 0.5 1.4 1 1 0 1 1 1 1 Phosphoesterase family Sugar_tr PF00083.19 KUM58971.1 - 4.5e-83 279.3 31.8 5.2e-83 279.1 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM58971.1 - 7.4e-28 97.2 28.3 7.8e-27 93.8 18.1 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KUM58971.1 - 0.00057 18.2 3.3 0.00057 18.2 2.3 2.1 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) RAMP4 PF06624.7 KUM58971.1 - 1.3 8.6 4.0 4.2 6.9 0.0 2.4 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 Ribosomal_L44 PF00935.14 KUM58972.1 - 2.5e-33 113.8 12.6 4.6e-33 113.0 8.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L44 Acetyltransf_1 PF00583.19 KUM58973.1 - 2.1e-06 27.6 0.0 3.4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KUM58973.1 - 3.3e-06 27.1 0.0 5.9e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyoxalase PF00903.20 KUM58973.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Fungal_trans PF04082.13 KUM58974.1 - 4.2e-16 58.5 0.7 7.5e-16 57.7 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM58974.1 - 9.5e-08 31.8 6.2 1.7e-07 31.0 4.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 KUM58974.1 - 1.3 9.2 11.2 0.28 11.3 5.2 1.8 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region MFS_1 PF07690.11 KUM58975.1 - 1e-43 149.4 37.3 1e-43 149.4 25.9 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM58975.1 - 7.6e-12 44.5 3.4 7.6e-12 44.5 2.3 2.3 2 1 1 3 3 3 1 Sugar (and other) transporter OAD_gamma PF04277.8 KUM58975.1 - 4.5 7.7 6.3 6 7.3 0.0 3.2 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DUF3824 PF12868.2 KUM58976.1 - 5.9e-18 66.1 28.9 5.9e-18 66.1 20.1 3.2 2 1 1 3 3 3 1 Domain of unknwon function (DUF3824) Vac7 PF12751.2 KUM58977.1 - 1.8e-201 669.0 8.3 1.8e-201 669.0 5.8 1.9 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 TIM-br_sig_trns PF09370.5 KUM58978.1 - 9.1e-136 451.1 1.3 1e-135 450.9 0.9 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 KUM58978.1 - 0.00022 20.4 0.2 0.00022 20.4 0.1 1.8 2 0 0 2 2 2 1 Nitronate monooxygenase CorA PF01544.13 KUM58980.1 - 3.5e-40 137.8 0.4 8.2e-40 136.6 0.2 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein FtsX PF02687.16 KUM58980.1 - 0.32 10.7 0.2 0.51 10.1 0.1 1.3 1 0 0 1 1 1 0 FtsX-like permease family XPC-binding PF09280.6 KUM58981.1 - 7.2e-22 76.6 10.6 1.4e-21 75.6 7.3 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 KUM58981.1 - 1.2e-18 66.2 0.9 1.2e-18 66.2 0.6 1.8 2 0 0 2 2 2 1 Ubiquitin family UBA PF00627.26 KUM58981.1 - 3.5e-16 58.5 0.8 1.8e-08 33.9 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.3 KUM58981.1 - 1.2e-08 34.4 2.5 2.5e-08 33.4 1.7 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 KUM58981.1 - 0.00051 19.9 0.0 0.00091 19.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KUM58981.1 - 0.0025 17.9 0.0 0.0059 16.7 0.0 1.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain UBA_3 PF09288.5 KUM58981.1 - 0.034 13.7 0.0 3.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Glyco_transf_22 PF03901.12 KUM58982.1 - 1.8e-60 205.0 25.1 2.3e-60 204.7 17.4 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family O-antigen_lig PF13425.1 KUM58982.1 - 3.7 7.5 13.8 0.24 11.3 1.2 3.3 3 1 0 3 3 3 0 O-antigen ligase like membrane protein Skp1 PF01466.14 KUM58983.1 - 8.6e-40 134.6 2.2 1.4e-39 133.9 1.6 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KUM58983.1 - 3.3e-23 81.5 0.1 8e-23 80.3 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.1 KUM58983.1 - 0.097 12.6 0.5 0.15 12.0 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) APH PF01636.18 KUM58984.1 - 0.0021 17.8 0.0 0.0021 17.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family ABC_membrane PF00664.18 KUM58985.1 - 1.3e-83 280.6 35.8 3.1e-44 151.4 8.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KUM58985.1 - 1.4e-67 226.2 0.0 1.2e-32 113.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KUM58985.1 - 3e-14 52.8 0.0 2e-05 23.9 0.3 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KUM58985.1 - 5e-10 39.8 0.1 1.4 8.8 0.0 4.5 3 1 0 4 4 4 4 AAA domain AAA_29 PF13555.1 KUM58985.1 - 1.6e-08 33.9 0.5 0.00056 19.3 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KUM58985.1 - 1.9e-08 34.5 1.1 0.0015 18.5 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.4 KUM58985.1 - 2.6e-08 32.9 1.2 0.0021 16.7 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 KUM58985.1 - 4.9e-08 33.8 0.0 0.011 16.6 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 KUM58985.1 - 2.9e-07 30.7 0.3 4.6 7.4 0.0 4.8 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 KUM58985.1 - 9.2e-06 24.9 0.0 0.13 11.4 0.0 2.8 3 0 0 3 3 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KUM58985.1 - 2.4e-05 24.4 3.8 0.22 11.6 0.1 4.2 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KUM58985.1 - 3.9e-05 23.3 1.9 1.9 8.0 0.0 4.1 4 0 0 4 4 4 2 AAA domain AAA_10 PF12846.2 KUM58985.1 - 5e-05 22.8 0.9 1.4 8.3 0.1 4.2 4 0 0 4 4 4 2 AAA-like domain AAA_25 PF13481.1 KUM58985.1 - 0.00022 20.7 3.5 0.43 9.9 0.0 3.4 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.1 KUM58985.1 - 0.00029 21.1 0.0 0.56 10.5 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 KUM58985.1 - 0.00029 20.7 0.0 0.91 9.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KUM58985.1 - 0.0011 18.7 0.5 2.8 7.6 0.0 3.2 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 KUM58985.1 - 0.0023 17.7 5.7 0.69 9.8 0.2 3.7 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 KUM58985.1 - 0.0024 17.7 0.0 1.2 9.1 0.0 3.6 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.1 KUM58985.1 - 0.0024 17.5 0.3 1.6 8.5 0.1 3.1 2 0 0 2 2 2 1 Part of AAA domain Rad17 PF03215.10 KUM58985.1 - 0.0039 15.9 0.1 0.072 11.7 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein MobB PF03205.9 KUM58985.1 - 0.0045 16.6 1.3 4.6 6.9 0.0 3.4 3 1 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 KUM58985.1 - 0.0092 15.0 0.3 2 7.4 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin SRP54 PF00448.17 KUM58985.1 - 0.011 15.2 0.2 1.1 8.6 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_23 PF13476.1 KUM58985.1 - 0.012 16.0 0.1 8.7 6.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 KUM58985.1 - 0.017 15.3 0.1 3.3 7.9 0.0 3.1 3 0 0 3 3 2 0 RNA helicase AAA_28 PF13521.1 KUM58985.1 - 0.018 15.0 0.4 1.3 9.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain PRK PF00485.13 KUM58985.1 - 0.05 13.1 0.0 2.8 7.4 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.18 KUM58985.1 - 0.54 10.2 2.3 10 6.1 0.1 3.2 3 1 0 3 3 2 0 50S ribosome-binding GTPase Ytp1 PF10355.4 KUM58986.1 - 4.1e-87 291.8 16.3 8.5e-87 290.7 11.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KUM58986.1 - 4e-18 64.9 2.7 4e-18 64.9 1.9 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) S1FA PF04689.8 KUM58986.1 - 1.7 8.5 4.2 3.8 7.4 0.4 2.5 2 0 0 2 2 2 0 DNA binding protein S1FA ThiF PF00899.16 KUM58987.1 - 3.3e-15 56.0 0.1 5e-15 55.5 0.1 1.3 1 0 0 1 1 1 1 ThiF family Asp_protease PF09668.5 KUM58989.1 - 1.2e-60 202.5 0.1 1.7e-60 201.9 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 KUM58989.1 - 2.1e-10 40.9 0.0 4.2e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease UBA PF00627.26 KUM58989.1 - 3.2e-07 29.9 0.0 7.2e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain ubiquitin PF00240.18 KUM58989.1 - 8.6e-07 28.2 0.0 1.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family RVP_2 PF08284.6 KUM58989.1 - 3.1e-06 27.1 0.0 5.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KUM58989.1 - 1.6e-05 24.5 0.0 4.9e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Rad60-SLD PF11976.3 KUM58989.1 - 0.00067 19.3 0.1 0.0014 18.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RVP PF00077.15 KUM58989.1 - 0.0017 18.2 0.0 0.0057 16.5 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.1 KUM58989.1 - 0.028 13.9 0.0 0.067 12.7 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain DUF2781 PF10914.3 KUM58990.1 - 2.1e-38 131.4 13.6 6.4e-38 129.8 9.4 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2781) SOG2 PF10428.4 KUM58991.1 - 1.7 7.1 8.9 2.3 6.7 6.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Sds3 PF08598.6 KUM58992.1 - 0.0004 19.9 1.8 0.0004 19.9 1.3 2.6 2 1 0 2 2 2 1 Sds3-like Nucleoporin_C PF03177.9 KUM58993.1 - 1.6e-135 452.9 3.3 2.1e-135 452.5 2.3 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KUM58993.1 - 1.3e-86 291.0 0.4 1.9e-86 290.4 0.3 1.3 1 0 0 1 1 1 1 Nup133 N terminal like TauD PF02668.11 KUM58994.1 - 3.6e-45 154.6 0.1 4.5e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Rot1 PF10681.4 KUM58995.1 - 8.3e-85 283.4 0.0 9.5e-85 283.2 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal JmjN PF02375.12 KUM58995.1 - 0.091 12.3 0.3 0.18 11.3 0.2 1.4 1 0 0 1 1 1 0 jmjN domain YqeY PF09424.5 KUM58996.1 - 4.9e-19 68.5 3.4 6.1e-19 68.2 2.4 1.1 1 0 0 1 1 1 1 Yqey-like protein Aldedh PF00171.17 KUM58997.1 - 7e-165 548.8 0.4 8e-165 548.6 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KUM58997.1 - 0.02 13.6 0.0 0.029 13.0 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) NMT PF01233.14 KUM58998.1 - 3e-79 264.2 0.2 7.5e-79 263.0 0.0 1.7 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 KUM58998.1 - 2.8e-77 258.4 0.2 6.2e-77 257.2 0.0 1.7 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 KUM58998.1 - 6.2e-07 29.3 0.1 5e-06 26.3 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KUM58998.1 - 0.0015 18.7 0.1 0.0046 17.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF427 PF04248.7 KUM58998.1 - 0.0075 15.9 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF427) RRN9 PF10680.4 KUM58999.1 - 1.3e-14 53.7 0.3 6.6e-14 51.4 0.2 2.3 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor Nucleoporin_FG PF13634.1 KUM58999.1 - 0.11 12.6 0.1 0.22 11.7 0.1 1.4 1 0 0 1 1 1 0 Nucleoporin FG repeat region zf-C2H2_4 PF13894.1 KUM58999.1 - 7.1 7.2 7.5 0.89 10.0 1.3 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger Pkinase PF00069.20 KUM59002.1 - 2.7e-18 66.0 0.0 3.3e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM59002.1 - 6.6e-11 41.7 0.0 8.2e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KUM59003.1 - 1e-22 80.5 0.0 1.2e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM59003.1 - 0.11 11.5 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase MARVEL PF01284.18 KUM59004.1 - 2.9e-14 53.1 9.5 3.4e-14 52.8 6.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain Syja_N PF02383.13 KUM59005.1 - 4.5e-93 311.5 0.0 5.8e-93 311.1 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain GTP_EFTU PF00009.22 KUM59006.1 - 8.3e-55 185.1 0.3 1.4e-54 184.3 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KUM59006.1 - 9.4e-33 111.8 0.0 2.1e-32 110.8 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 KUM59006.1 - 2e-29 101.5 0.1 6.4e-29 99.9 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 KUM59006.1 - 1.9e-22 78.9 0.0 4.8e-22 77.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KUM59006.1 - 2.5e-12 46.7 0.0 6.2e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ribosomal_L36 PF00444.13 KUM59007.1 - 6.3e-20 70.8 8.3 9.7e-20 70.2 5.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 Crust_neurohorm PF01147.12 KUM59007.1 - 0.037 13.3 0.2 0.055 12.7 0.2 1.2 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family Ras PF00071.17 KUM59010.1 - 5.6e-59 198.1 0.2 6.5e-59 197.9 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KUM59010.1 - 7e-20 71.6 0.1 1.6e-19 70.5 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KUM59010.1 - 6.9e-15 54.7 0.0 8.5e-15 54.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KUM59010.1 - 2.3e-08 33.7 0.0 4.1e-08 32.8 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KUM59010.1 - 3.9e-08 32.7 0.0 4.9e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KUM59010.1 - 6.1e-06 26.1 0.0 8.4e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KUM59010.1 - 0.0041 17.2 0.0 0.76 9.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KUM59010.1 - 0.027 14.4 0.4 0.14 12.1 0.2 2.1 1 1 1 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 KUM59010.1 - 0.029 13.5 0.1 0.11 11.6 0.0 1.9 1 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 KUM59010.1 - 0.08 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mitofilin PF09731.4 KUM59011.1 - 2.9e-147 491.8 27.0 3.8e-147 491.4 18.7 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Pex14_N PF04695.8 KUM59011.1 - 0.0025 17.8 2.8 0.69 9.9 0.0 2.6 2 0 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region Exonuc_VII_L PF02601.10 KUM59011.1 - 1.6 7.8 16.6 0.088 11.9 6.8 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF479 PF04336.7 KUM59011.1 - 2.6 8.1 7.6 4 7.6 0.0 3.6 2 1 1 3 3 3 0 Protein of unknown function, DUF479 DUF2115 PF09888.4 KUM59011.1 - 3.6 7.6 6.3 6.2 6.8 1.7 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) DNA_pol_viral_N PF00242.12 KUM59011.1 - 5.6 5.8 9.3 0.21 10.6 2.3 1.5 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain Mur_ligase_M PF08245.7 KUM59012.1 - 8.4e-07 29.2 2.0 0.00014 21.9 0.7 3.7 2 1 0 2 2 2 1 Mur ligase middle domain DUF1471 PF07338.8 KUM59012.1 - 0.053 13.1 0.1 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) PALP PF00291.20 KUM59013.1 - 5.2e-72 242.6 0.4 8.7e-72 241.9 0.1 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 KUM59013.1 - 4.6e-47 157.5 0.0 1.6e-22 78.8 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase HIG_1_N PF04588.8 KUM59014.1 - 1.4e-12 47.1 0.3 1.8e-12 46.7 0.2 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF1491 PF07372.7 KUM59014.1 - 0.068 13.0 1.5 0.1 12.4 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) ATP-synt_E PF05680.7 KUM59014.1 - 0.83 9.6 6.1 0.32 10.9 1.7 1.9 1 1 1 2 2 2 0 ATP synthase E chain bZIP_1 PF00170.16 KUM59015.1 - 1.7e-08 34.2 7.9 2.7e-08 33.6 5.4 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KUM59015.1 - 1e-07 31.6 7.9 1.7e-07 30.9 5.5 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KUM59015.1 - 0.35 11.1 6.5 0.27 11.5 3.7 1.5 1 1 0 1 1 1 0 bZIP Maf transcription factor Aminotran_3 PF00202.16 KUM59016.1 - 1.2e-102 343.2 0.0 1.5e-102 342.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Spt4 PF06093.8 KUM59017.1 - 1.2e-32 111.5 0.3 1.5e-32 111.3 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger RNHCP PF12647.2 KUM59017.1 - 0.046 13.5 0.5 0.061 13.1 0.3 1.2 1 0 0 1 1 1 0 RNHCP domain DNA_ligase_ZBD PF03119.11 KUM59017.1 - 0.078 12.6 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain DUF459 PF04311.8 KUM59017.1 - 0.11 11.2 0.0 0.13 11.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF459) Cut12 PF11500.3 KUM59020.1 - 2.4e-47 160.4 6.5 2.4e-47 160.4 4.5 4.0 3 1 0 3 3 3 1 Spindle pole body formation-associated protein FUSC PF04632.7 KUM59020.1 - 1.4 7.2 12.5 2.3 6.5 8.6 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2730 PF10805.3 KUM59020.1 - 3 7.5 22.0 0.21 11.3 0.8 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) Metallophos PF00149.23 KUM59022.1 - 3.5e-39 134.2 0.1 5.2e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 KUM59022.1 - 3.7e-28 97.3 0.1 7.8e-28 96.3 0.1 1.5 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 KUM59022.1 - 7.3e-21 73.5 1.6 4e-14 52.0 0.0 3.0 1 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 KUM59022.1 - 5.7e-09 35.2 2.9 0.00035 20.0 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KUM59022.1 - 6e-09 35.1 3.5 0.047 13.6 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KUM59022.1 - 2.5e-06 27.9 3.2 0.016 15.8 0.1 3.2 2 2 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KUM59022.1 - 0.00056 20.2 0.6 0.24 11.7 0.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KUM59022.1 - 0.0024 17.7 0.3 0.14 11.9 0.0 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KUM59022.1 - 0.014 15.5 1.0 1.7 9.0 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KUM59022.1 - 0.088 13.4 4.8 28 5.7 0.0 4.4 3 1 2 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KUM59022.1 - 0.1 12.5 0.2 0.26 11.1 0.1 1.7 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat DUF89 PF01937.14 KUM59023.1 - 1.1e-135 452.0 0.0 1.3e-135 451.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Sugar_tr PF00083.19 KUM59024.1 - 3.6e-71 240.0 18.2 4.1e-71 239.8 12.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM59024.1 - 0.0015 17.2 33.8 0.0071 15.0 16.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CTDII PF01556.13 KUM59025.1 - 3.6e-24 84.4 0.5 2.4e-21 75.4 0.0 3.0 2 1 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 KUM59025.1 - 8e-05 22.3 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain PIG-X PF08320.7 KUM59026.1 - 1.1e-70 237.1 0.0 1.5e-70 236.6 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 Pkinase PF00069.20 KUM59027.1 - 3.7e-65 219.6 0.6 4.8e-37 127.5 0.0 5.4 6 1 0 6 6 6 4 Protein kinase domain Pkinase_Tyr PF07714.12 KUM59027.1 - 3.4e-36 124.6 0.0 8e-19 67.7 0.0 3.7 3 1 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 KUM59027.1 - 4.6e-15 55.4 0.0 1.6e-14 53.7 0.0 2.0 2 0 0 2 2 2 1 RWD domain APH PF01636.18 KUM59027.1 - 0.00042 20.1 4.8 0.001 18.8 0.0 2.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KUM59027.1 - 0.00074 18.5 0.0 0.69 8.8 0.0 2.5 2 0 0 2 2 2 2 Kinase-like DUF4267 PF14087.1 KUM59028.1 - 1.9e-33 114.4 3.4 2.3e-33 114.1 2.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Acyl_transf_3 PF01757.17 KUM59028.1 - 0.08 11.7 4.6 0.093 11.5 3.2 1.1 1 0 0 1 1 1 0 Acyltransferase family TGS PF02824.16 KUM59029.1 - 2e-19 69.1 0.5 4e-19 68.1 0.1 1.7 2 0 0 2 2 2 1 TGS domain Swi5 PF07061.6 KUM59029.1 - 0.06 13.1 0.3 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 Swi5 DUF4533 PF15047.1 KUM59029.1 - 0.32 10.4 1.2 0.4 10.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4533) MMR_HSR1 PF01926.18 KUM59030.1 - 5.8e-19 68.1 0.0 9.2e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KUM59030.1 - 4.8e-13 48.6 0.0 6.3e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KUM59030.1 - 7.7e-05 22.5 2.7 0.028 14.2 0.0 2.4 2 1 1 3 3 3 2 Dynamin family Miro PF08477.8 KUM59030.1 - 0.0011 19.3 0.0 0.0023 18.4 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein MCM PF00493.18 KUM59030.1 - 0.0082 14.9 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 MCM2/3/5 family ArgK PF03308.11 KUM59030.1 - 0.01 14.6 0.1 0.019 13.7 0.1 1.5 1 0 0 1 1 1 0 ArgK protein AIG1 PF04548.11 KUM59030.1 - 0.047 12.7 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 AIG1 family SRPRB PF09439.5 KUM59030.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RRM_1 PF00076.17 KUM59031.1 - 2.9e-07 29.9 0.0 6.7e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM59031.1 - 2.3e-06 27.3 0.0 5.5e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM59031.1 - 0.00011 22.1 0.0 0.00027 20.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KUM59031.1 - 0.0054 16.4 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif HGTP_anticodon2 PF12745.2 KUM59032.1 - 1.1e-82 277.2 3.7 1.7e-82 276.6 2.6 1.3 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_His PF13393.1 KUM59032.1 - 0.00025 20.2 0.0 0.00051 19.2 0.0 1.5 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.15 KUM59032.1 - 0.0086 15.9 0.1 0.019 14.8 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain Fungal_trans PF04082.13 KUM59033.1 - 1.3e-09 37.2 0.1 3.6e-09 35.8 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM59033.1 - 1.8e-08 34.1 11.5 2.9e-08 33.4 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CPSase_sm_chain PF00988.17 KUM59036.1 - 9.2e-46 154.5 0.0 1.6e-45 153.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 KUM59036.1 - 3.3e-45 153.8 0.0 4.8e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KUM59036.1 - 4.3e-06 26.3 0.2 0.00044 19.7 0.0 2.4 1 1 1 2 2 2 2 Peptidase C26 AAA PF00004.24 KUM59037.1 - 3.3e-65 218.2 0.0 1.3e-41 141.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KUM59037.1 - 7.1e-13 48.9 1.2 0.0017 18.3 0.1 4.3 3 2 0 4 4 4 3 AAA ATPase domain AAA_5 PF07728.9 KUM59037.1 - 1.7e-09 37.5 0.4 0.0036 17.0 0.0 3.5 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KUM59037.1 - 1.5e-07 31.6 5.6 0.15 12.1 0.1 4.7 3 2 2 5 5 5 2 AAA domain AAA_14 PF13173.1 KUM59037.1 - 2.9e-07 30.4 0.0 0.014 15.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.13 KUM59037.1 - 5.9e-07 29.3 0.0 3.9e-05 23.4 0.0 2.9 2 2 0 2 2 2 1 Bacterial dnaA protein AAA_25 PF13481.1 KUM59037.1 - 2e-06 27.3 0.3 0.75 9.1 0.0 4.2 3 1 0 3 3 3 2 AAA domain IstB_IS21 PF01695.12 KUM59037.1 - 9e-06 25.2 0.0 0.018 14.4 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_17 PF13207.1 KUM59037.1 - 9.7e-06 26.4 0.0 0.096 13.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 KUM59037.1 - 1.2e-05 25.1 0.4 0.009 15.7 0.1 3.0 2 2 1 3 3 3 1 Archaeal ATPase AAA_28 PF13521.1 KUM59037.1 - 1.5e-05 24.9 0.1 0.067 13.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain RuvB_N PF05496.7 KUM59037.1 - 2.4e-05 23.5 0.0 0.015 14.3 0.0 3.3 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 KUM59037.1 - 4.7e-05 22.4 0.0 0.073 11.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) TIP49 PF06068.8 KUM59037.1 - 0.00011 21.0 1.0 0.029 13.1 0.0 2.5 3 0 0 3 3 3 2 TIP49 C-terminus AAA_2 PF07724.9 KUM59037.1 - 0.00015 21.7 0.0 0.015 15.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 KUM59037.1 - 0.00029 20.9 0.0 1.4 9.1 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Rad17 PF03215.10 KUM59037.1 - 0.00044 19.0 0.1 0.0034 16.1 0.0 2.3 2 1 1 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 KUM59037.1 - 0.00067 19.2 1.0 0.052 13.1 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KUM59037.1 - 0.0016 18.1 0.0 2.2 8.0 0.0 3.3 3 0 0 3 3 3 1 Part of AAA domain Sigma54_activ_2 PF14532.1 KUM59037.1 - 0.0047 16.9 0.0 0.52 10.3 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain ABC_tran PF00005.22 KUM59037.1 - 0.005 17.1 0.2 0.72 10.1 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_33 PF13671.1 KUM59037.1 - 0.006 16.4 0.1 1.1 9.1 0.1 2.9 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KUM59037.1 - 0.008 15.2 0.0 1 8.4 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.7 KUM59037.1 - 0.0095 15.6 3.6 0.62 9.6 0.3 3.6 3 1 1 4 4 4 1 NACHT domain AAA_11 PF13086.1 KUM59037.1 - 0.013 15.1 0.0 1.7 8.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KUM59037.1 - 0.015 15.5 0.0 0.04 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KUM59037.1 - 0.018 14.2 0.1 3.2 6.8 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Miro PF08477.8 KUM59037.1 - 0.022 15.2 0.1 0.14 12.6 0.0 2.5 2 0 0 2 2 1 0 Miro-like protein AAA_30 PF13604.1 KUM59037.1 - 0.035 13.6 0.0 0.75 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.5 KUM59037.1 - 0.036 13.2 0.1 0.84 8.8 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.1 KUM59037.1 - 0.047 13.9 0.0 0.41 10.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ras PF00071.17 KUM59038.1 - 1.8e-65 219.2 0.0 2.2e-65 218.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KUM59038.1 - 7.5e-19 68.3 0.0 1e-18 67.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KUM59038.1 - 5.8e-14 51.7 0.0 7.5e-14 51.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KUM59038.1 - 1.1e-06 28.1 0.0 2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KUM59038.1 - 2.4e-06 26.8 0.0 2.9e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KUM59038.1 - 0.0058 16.5 0.0 0.008 16.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KUM59038.1 - 0.022 14.0 0.0 0.1 11.8 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.5 KUM59038.1 - 0.033 13.3 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF258 PF03193.11 KUM59038.1 - 0.048 12.8 0.0 0.19 10.9 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 KUM59038.1 - 0.1 12.1 0.0 0.29 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 KUM59038.1 - 0.12 12.6 0.0 6.1 7.0 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KUM59038.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.8 1 1 1 2 2 2 0 AAA domain PI3_PI4_kinase PF00454.22 KUM59039.1 - 3.5e-50 170.6 0.1 7.2e-50 169.6 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 KUM59039.1 - 2.5e-44 151.7 2.4 2.5e-44 151.7 1.7 2.6 3 0 0 3 3 3 1 FAT domain UME PF08064.8 KUM59039.1 - 3.2e-40 136.3 0.4 1.3e-39 134.4 0.3 2.2 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.15 KUM59039.1 - 8.7e-14 50.6 0.0 2.5e-13 49.2 0.0 1.9 1 0 0 1 1 1 1 FATC domain TPR_11 PF13414.1 KUM59039.1 - 2.8e-06 26.8 0.8 0.57 9.8 0.0 4.1 3 1 1 4 4 4 2 TPR repeat TPR_14 PF13428.1 KUM59039.1 - 0.00011 22.4 2.4 9.4 7.1 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KUM59039.1 - 0.00016 22.2 0.3 1.8 9.3 0.0 4.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KUM59039.1 - 0.0062 16.2 0.8 25 4.9 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KUM59039.1 - 0.031 14.6 3.3 0.46 10.8 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 KUM59039.1 - 0.11 12.7 0.5 5 7.5 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat RRM_1 PF00076.17 KUM59040.1 - 5e-14 51.6 0.0 7.9e-14 51.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM59040.1 - 5.1e-11 42.3 0.0 1e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM59040.1 - 6.9e-07 29.0 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KUM59040.1 - 0.00054 19.7 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 RNA binding motif DUF1777 PF08648.7 KUM59040.1 - 0.0013 18.5 24.1 0.0019 17.9 16.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) NADH-u_ox-rdase PF10785.4 KUM59041.1 - 1.8e-34 117.7 0.1 2.8e-34 117.2 0.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 KUM59041.1 - 4.7e-34 115.9 0.2 6.9e-34 115.4 0.2 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit dCMP_cyt_deam_1 PF00383.17 KUM59042.1 - 2.9e-25 87.8 0.0 3.6e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 KUM59042.1 - 0.036 13.9 1.0 0.11 12.3 0.1 1.9 1 1 1 2 2 2 0 Bd3614-like deaminase RCC1 PF00415.13 KUM59043.1 - 2.7e-55 184.3 9.3 6.4e-12 45.4 0.1 8.3 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KUM59043.1 - 1.5e-29 100.8 39.8 1.1e-06 28.1 1.5 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat DUF966 PF06136.8 KUM59043.1 - 0.37 10.1 13.2 0.56 9.5 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Swi3 PF07962.7 KUM59044.1 - 5.7e-32 109.1 0.3 9.7e-32 108.4 0.2 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Y_phosphatase PF00102.22 KUM59045.1 - 7.5e-61 205.4 0.0 2.1e-59 200.7 0.0 2.3 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 KUM59045.1 - 9.5e-08 32.3 0.0 5e-07 30.0 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.15 KUM59045.1 - 0.0029 17.1 0.1 0.0065 16.0 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KUM59045.1 - 0.0051 17.0 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family COX16 PF14138.1 KUM59046.1 - 7.8e-30 102.8 0.1 1e-29 102.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 DUF1990 PF09348.5 KUM59046.1 - 0.092 12.3 0.6 2.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1990) Nic96 PF04097.9 KUM59047.1 - 1.6e-206 687.1 0.0 1.9e-206 686.9 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.1 KUM59047.1 - 0.92 9.7 52.2 0.13 12.5 28.5 2.3 2 0 0 2 2 2 0 Nucleoporin FG repeat region RibD_C PF01872.12 KUM59048.1 - 9.1e-30 103.7 0.0 1.3e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain Na_Ca_ex PF01699.19 KUM59049.1 - 3.6e-31 107.6 23.5 1.2e-18 67.0 6.3 3.8 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 KUM59049.1 - 7.3e-14 51.9 10.0 7.3e-14 51.9 6.9 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF307) FGGY_C PF02782.11 KUM59050.1 - 4.2e-51 173.3 0.2 6.1e-51 172.8 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KUM59050.1 - 4.9e-24 84.9 0.0 3.4e-21 75.6 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 KUM59050.1 - 0.059 12.6 0.0 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family F-box-like_2 PF13013.1 KUM59052.1 - 0.014 15.0 0.1 0.027 14.1 0.1 1.4 1 0 0 1 1 1 0 F-box-like domain F-box PF00646.28 KUM59052.1 - 0.027 14.1 0.0 0.059 13.0 0.0 1.5 1 0 0 1 1 1 0 F-box domain Mei4 PF13971.1 KUM59052.1 - 0.028 13.3 0.1 0.042 12.8 0.1 1.1 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 Nucleoplasmin PF03066.10 KUM59052.1 - 0.073 12.5 1.7 0.12 11.8 1.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin Alginate_lyase PF05426.7 KUM59053.1 - 1.3e-20 73.9 2.1 2.2e-20 73.1 1.5 1.3 1 1 0 1 1 1 1 Alginate lyase PetL PF05115.9 KUM59053.1 - 0.25 11.2 3.8 0.7 9.8 2.6 1.8 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) Glyco_hydro_88 PF07470.8 KUM59054.1 - 8.2e-19 67.8 0.4 1.2e-18 67.3 0.3 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_28 PF00295.12 KUM59055.1 - 1.4e-09 37.3 0.6 2.2e-09 36.7 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 KUM59055.1 - 0.0037 17.0 16.7 0.065 12.9 5.5 2.8 2 1 1 3 3 3 2 Right handed beta helix region NosD PF05048.8 KUM59055.1 - 0.015 14.4 2.0 0.028 13.5 1.4 1.5 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) MFS_1 PF07690.11 KUM59056.1 - 5.6e-36 123.9 23.4 5.6e-36 123.9 16.2 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1003 PF06210.6 KUM59056.1 - 0.042 13.7 0.0 0.18 11.7 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) TMEM154 PF15102.1 KUM59056.1 - 0.052 13.2 7.5 0.089 12.4 0.0 2.8 3 0 0 3 3 3 0 TMEM154 protein family Alginate_lyase PF05426.7 KUM59057.1 - 5.8e-15 55.3 3.0 1.4e-14 54.1 2.1 1.5 1 1 0 1 1 1 1 Alginate lyase UDPGT PF00201.13 KUM59058.1 - 4.8e-20 71.5 0.0 1.2e-18 67.0 0.0 2.6 2 1 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 KUM59058.1 - 7.8e-07 28.5 0.0 0.0014 17.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 1 Glyco_transf_28 PF03033.15 KUM59058.1 - 0.021 14.5 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.11 KUM59058.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Fungal_trans PF04082.13 KUM59059.1 - 2.6e-21 75.6 0.3 4.8e-21 74.7 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM59059.1 - 2.6e-09 36.8 11.8 5.1e-09 35.8 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Synaptobrevin PF00957.16 KUM59060.1 - 0.0011 18.5 0.6 0.0016 18.0 0.4 1.2 1 0 0 1 1 1 1 Synaptobrevin T2SF PF00482.18 KUM59060.1 - 0.037 13.9 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F RskA PF10099.4 KUM59060.1 - 0.078 12.7 0.2 0.078 12.7 0.1 1.6 2 0 0 2 2 2 0 Anti-sigma-K factor rskA PID_2 PF14719.1 KUM59060.1 - 0.13 11.9 0.1 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) FH2 PF02181.18 KUM59061.1 - 3.5e-87 292.6 1.5 3.5e-87 292.6 1.0 1.9 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 KUM59061.1 - 3.3e-68 228.7 0.0 3.3e-68 228.7 0.0 2.3 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 KUM59061.1 - 3.5e-53 179.9 0.6 3.9e-52 176.5 0.1 2.6 1 1 1 2 2 2 1 Diaphanous FH3 Domain zf-C2H2_2 PF12756.2 KUM59063.1 - 0.016 15.3 0.2 0.028 14.5 0.1 1.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_7 PF15269.1 KUM59063.1 - 0.083 12.7 5.2 1.4 8.7 1.5 2.3 2 0 0 2 2 2 0 Zinc-finger TrmE_N PF10396.4 KUM59064.1 - 1.6e-35 121.5 0.0 3.4e-35 120.4 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 KUM59064.1 - 8.5e-22 77.3 0.0 2.8e-21 75.6 0.0 2.0 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 KUM59064.1 - 8.6e-18 64.3 0.0 1.5e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KUM59064.1 - 3.5e-05 23.1 0.1 0.00011 21.5 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KUM59064.1 - 9.2e-05 22.3 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 KUM59064.1 - 0.00025 21.5 0.1 0.0011 19.3 0.1 2.1 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KUM59064.1 - 0.0003 20.2 0.0 0.057 12.8 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Glyco_hydro_3_C PF01915.17 KUM59064.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain AAA_24 PF13479.1 KUM59064.1 - 0.14 11.7 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain tRNA-synt_1 PF00133.17 KUM59065.1 - 1.5e-54 185.0 0.0 4.8e-34 117.3 0.1 6.3 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 KUM59065.1 - 2.8e-39 134.3 0.0 4.3e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 KUM59065.1 - 5.4e-29 101.0 0.0 1.8e-22 79.5 0.0 4.0 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KUM59065.1 - 5e-10 39.3 0.0 1.4e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 KUM59065.1 - 0.0004 19.2 0.0 0.00071 18.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) adh_short PF00106.20 KUM59066.1 - 5.2e-22 78.5 0.0 7.1e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM59066.1 - 8.7e-12 45.0 0.0 1.3e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM59066.1 - 1.5e-06 27.8 0.0 2.4e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KUM59066.1 - 0.0005 20.1 0.0 0.00087 19.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KUM59066.1 - 0.001 18.0 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KUM59066.1 - 0.0022 16.9 0.0 0.0028 16.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 KUM59066.1 - 0.0042 16.3 0.0 0.0072 15.6 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 KUM59066.1 - 0.01 14.5 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 KUM59066.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 KUM59066.1 - 0.064 12.1 0.0 4.2 6.2 0.0 2.4 2 1 1 3 3 3 0 Male sterility protein 2-Hacid_dh_C PF02826.14 KUM59067.1 - 3.6e-52 176.0 0.0 6.1e-52 175.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KUM59067.1 - 3.9e-15 55.4 0.0 5.3e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KUM59067.1 - 0.0011 18.8 0.0 0.0027 17.5 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Suc_Fer-like PF06999.7 KUM59068.1 - 2.9e-45 155.0 0.0 4.1e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Sec1 PF00995.18 KUM59069.1 - 3.4e-135 451.8 0.0 3.9e-135 451.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Glyco_tran_WecB PF03808.8 KUM59069.1 - 0.024 14.0 0.0 4.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family MBOAT PF03062.14 KUM59070.1 - 1e-47 162.8 7.0 1.9e-47 162.0 4.8 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 KUM59071.1 - 6.4e-25 87.0 0.4 1.6e-24 85.7 0.1 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family DUF457 PF04307.9 KUM59071.1 - 0.067 12.5 0.2 0.11 11.7 0.1 1.5 1 0 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) FA_desaturase PF00487.19 KUM59072.1 - 1.2e-24 87.1 16.3 2.2e-24 86.3 11.3 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KUM59072.1 - 6.3e-06 26.2 0.0 1.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) p450 PF00067.17 KUM59073.1 - 2.6e-26 92.1 0.0 3.6e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Velvet PF11754.3 KUM59074.1 - 3.2e-41 141.2 0.0 6.4e-41 140.1 0.0 1.4 1 1 0 1 1 1 1 Velvet factor Rad51 PF08423.6 KUM59075.1 - 3.9e-20 71.8 0.0 8.9e-20 70.6 0.0 1.5 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 KUM59075.1 - 2.1e-08 33.7 0.0 6.9e-08 32.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 KUM59075.1 - 0.083 12.0 0.9 0.96 8.5 0.6 2.3 1 1 0 1 1 1 0 KaiC DnaB_C PF03796.10 KUM59075.1 - 0.095 11.5 0.2 0.17 10.7 0.1 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain ER-remodelling PF14755.1 KUM59075.1 - 5 7.1 11.3 0.054 13.5 1.5 2.3 3 0 0 3 3 3 0 Intracellular membrane remodeller TRAPPC10 PF12584.3 KUM59076.1 - 1.6e-38 131.4 0.0 4.4e-38 130.0 0.0 1.8 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.3 KUM59076.1 - 0.016 14.6 0.4 0.03 13.8 0.3 1.5 1 0 0 1 1 1 0 Foie gras liver health family 1 Glyco_hydro_61 PF03443.9 KUM59077.1 - 2.3e-84 282.5 0.5 2.3e-84 282.5 0.3 2.2 2 1 0 2 2 2 1 Glycosyl hydrolase family 61 DUF605 PF04652.11 KUM59077.1 - 0.11 11.8 18.9 0.15 11.4 13.1 1.1 1 0 0 1 1 1 0 Vta1 like Herpes_BLLF1 PF05109.8 KUM59077.1 - 0.21 9.4 40.2 0.27 9.1 27.8 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) TIG PF01833.19 KUM59078.1 - 4.4e-12 45.8 0.3 1.8e-11 43.8 0.2 2.1 1 0 0 1 1 1 1 IPT/TIG domain Ank_2 PF12796.2 KUM59078.1 - 4.7e-10 39.6 0.0 1.1e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KUM59078.1 - 3e-09 36.2 2.9 0.001 18.7 0.4 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 KUM59078.1 - 4.2e-08 33.1 2.0 3.4e-06 27.1 0.9 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KUM59078.1 - 7.1e-07 29.5 1.2 7.1e-06 26.3 0.3 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM59078.1 - 3e-06 26.9 0.7 0.12 12.7 0.2 3.0 3 0 0 3 3 3 2 Ankyrin repeat Aminotran_3 PF00202.16 KUM59079.1 - 9.9e-56 189.0 0.0 2.2e-55 187.8 0.0 1.6 2 1 0 2 2 2 1 Aminotransferase class-III p450 PF00067.17 KUM59080.1 - 6.7e-20 71.0 0.1 7.9e-20 70.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 SUI1 PF01253.17 KUM59081.1 - 1.2e-17 63.4 0.2 2.7e-17 62.3 0.2 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 Kin17_mid PF10357.4 KUM59081.1 - 0.02 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein zf-C2H2_4 PF13894.1 KUM59083.1 - 0.004 17.3 0.0 0.0072 16.5 0.0 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 KUM59083.1 - 0.031 14.6 0.0 0.052 13.9 0.0 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type Vps39_1 PF10366.4 KUM59084.1 - 1.6e-31 108.4 0.0 1.1e-28 99.3 0.0 3.2 2 1 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 KUM59084.1 - 8.2e-25 87.1 0.0 1.8e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 KUM59084.1 - 8.3e-20 71.3 0.0 1.5e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.15 KUM59084.1 - 9e-11 41.5 4.7 2.5e-09 36.8 2.4 2.6 2 0 0 2 2 2 1 Region in Clathrin and VPS TPR_1 PF00515.23 KUM59084.1 - 0.00011 21.6 0.8 2.4 7.9 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 KUM59084.1 - 0.0046 16.5 3.4 1.9 8.1 0.3 4.3 3 1 1 4 4 4 1 TPR repeat TPR_2 PF07719.12 KUM59084.1 - 0.065 13.1 1.9 21 5.3 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KUM59084.1 - 0.15 12.2 2.3 4 7.6 0.0 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 KUM59084.1 - 0.18 11.8 0.2 23 5.2 0.0 4.3 5 0 0 5 5 5 0 PPR repeat TPR_6 PF13174.1 KUM59084.1 - 0.23 11.9 1.3 3.6e+02 1.9 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KUM59084.1 - 0.5 10.3 15.1 11 6.0 0.9 5.5 4 1 2 6 6 6 0 Tetratricopeptide repeat Gon7 PF08738.5 KUM59085.1 - 2.3e-16 59.6 5.8 2.6e-14 53.0 0.6 2.0 1 1 1 2 2 2 2 Gon7 family HrpB7 PF09486.5 KUM59085.1 - 0.025 14.5 0.3 0.028 14.3 0.2 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) FlxA PF14282.1 KUM59085.1 - 0.026 14.4 1.4 0.031 14.2 1.0 1.1 1 0 0 1 1 1 0 FlxA-like protein PP_M1 PF03012.9 KUM59085.1 - 0.087 12.1 1.2 0.093 12.0 0.8 1.0 1 0 0 1 1 1 0 Phosphoprotein Rhamno_transf PF11316.3 KUM59085.1 - 0.094 11.8 0.1 0.1 11.7 0.1 1.0 1 0 0 1 1 1 0 Putative rhamnosyl transferase RRM_1 PF00076.17 KUM59086.1 - 4.4e-16 58.2 0.0 2e-12 46.5 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM59086.1 - 1.5e-15 56.9 0.0 2.5e-10 40.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM59086.1 - 6.1e-10 38.8 0.0 8.4e-05 22.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KUM59086.1 - 0.013 15.2 0.0 0.15 11.7 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 Laminin_G_2 PF02210.19 KUM59086.1 - 0.022 14.7 0.0 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 Laminin G domain 6PF2K PF01591.13 KUM59087.1 - 5.8e-77 257.7 0.0 7.9e-77 257.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KUM59087.1 - 1.4e-32 113.0 0.0 2.8e-32 112.0 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KUM59087.1 - 5.6e-07 29.5 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KUM59087.1 - 0.00024 20.3 0.0 0.00038 19.7 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 KUM59087.1 - 0.024 15.4 0.1 0.23 12.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 KUM59088.1 - 5e-16 59.1 0.0 1.8e-15 57.3 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KUM59088.1 - 1.2e-05 24.9 0.1 4.5e-05 23.1 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 KUM59088.1 - 0.00064 19.4 0.0 0.0017 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KUM59088.1 - 0.001 19.1 3.5 0.0034 17.5 0.5 2.8 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KUM59088.1 - 0.0016 18.0 0.1 0.0097 15.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KUM59088.1 - 0.0055 16.7 0.9 0.013 15.5 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KUM59088.1 - 0.01 15.7 0.0 0.053 13.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain NPR2 PF06218.6 KUM59088.1 - 0.06 12.0 0.0 0.06 12.0 0.0 1.7 2 0 0 2 2 2 0 Nitrogen permease regulator 2 ArgK PF03308.11 KUM59088.1 - 0.088 11.5 0.9 0.4 9.4 0.0 2.3 2 0 0 2 2 2 0 ArgK protein Mem_trans PF03547.13 KUM59088.1 - 0.16 10.2 0.4 0.21 9.8 0.3 1.4 1 0 0 1 1 1 0 Membrane transport protein Ldh_1_C PF02866.13 KUM59089.1 - 2e-43 148.1 0.0 3e-43 147.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 KUM59089.1 - 3.9e-42 143.4 0.0 6.6e-42 142.6 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KUM59089.1 - 0.0011 17.7 0.0 0.0015 17.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KUM59089.1 - 0.011 16.0 0.2 0.095 13.0 0.0 2.5 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KUM59089.1 - 0.033 13.2 0.0 0.41 9.7 0.0 2.6 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HbrB PF08539.6 KUM59090.1 - 2.2e-53 180.2 0.0 3.1e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 HbrB-like Sec7 PF01369.15 KUM59092.1 - 3e-64 216.2 0.8 1e-63 214.4 0.5 2.0 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KUM59092.1 - 4.5e-52 175.8 3.0 4.5e-52 175.8 2.1 3.1 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KUM59092.1 - 5.5e-32 109.1 1.5 7.7e-31 105.4 0.0 3.9 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) 2-oxoacid_dh PF00198.18 KUM59093.1 - 1.7e-75 253.2 0.2 2.2e-75 252.9 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KUM59093.1 - 8e-17 60.6 0.6 2.4e-16 59.1 0.4 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KUM59093.1 - 1.2e-12 47.1 0.8 3.3e-12 45.8 0.6 1.8 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.3 KUM59093.1 - 8.2 6.6 7.3 0.42 10.8 0.1 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3614) Pribosyltran_N PF13793.1 KUM59094.1 - 2.1e-43 146.7 0.1 2.9e-42 143.0 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KUM59094.1 - 4e-31 108.1 0.0 4.1e-26 91.8 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KUM59094.1 - 0.00018 21.2 0.5 0.0069 16.1 0.1 2.7 3 0 0 3 3 3 1 Phosphoribosyl transferase domain PLDc_2 PF13091.1 KUM59095.1 - 8.2e-14 51.4 0.0 7.1e-06 25.7 0.0 3.7 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.17 KUM59095.1 - 3.2e-10 39.4 6.2 3.3e-06 26.7 0.5 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif SseC PF04888.7 KUM59096.1 - 0.015 14.6 0.5 0.02 14.2 0.4 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family V-SNARE_C PF12352.3 KUM59097.1 - 6.2e-14 51.8 0.5 1.5e-13 50.5 0.2 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KUM59097.1 - 0.00042 19.9 0.0 0.0012 18.5 0.0 1.7 2 0 0 2 2 2 1 Sec20 BAR_2 PF10455.4 KUM59097.1 - 0.038 12.8 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking She9_MDM33 PF05546.6 KUM59097.1 - 0.043 13.3 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 She9 / Mdm33 family DUF1785 PF08699.5 KUM59097.1 - 0.15 11.4 0.2 0.36 10.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1785) NAD_binding_7 PF13241.1 KUM59098.1 - 3.6e-34 117.1 0.1 5.9e-34 116.4 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KUM59098.1 - 2.8e-32 109.8 0.0 4.5e-32 109.1 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 KUM59098.1 - 5.4e-15 54.0 0.0 9.6e-15 53.2 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Shikimate_DH PF01488.15 KUM59098.1 - 0.013 15.6 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 KUM59098.1 - 0.086 12.8 0.3 0.21 11.5 0.2 1.7 1 1 0 1 1 1 0 TrkA-N domain ThiF PF00899.16 KUM59098.1 - 0.2 11.5 1.7 0.26 11.1 0.1 1.9 1 1 1 2 2 2 0 ThiF family FGE-sulfatase PF03781.11 KUM59099.1 - 2.4e-10 40.2 0.9 4.1e-10 39.4 0.6 1.3 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 KUM59099.1 - 3.5e-06 27.3 1.2 9.3e-06 26.0 0.6 1.9 1 1 1 2 2 2 1 DinB superfamily ABC_membrane PF00664.18 KUM59100.1 - 1.6e-80 270.4 32.4 4.6e-41 141.0 11.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KUM59100.1 - 1.1e-66 223.2 0.1 3e-32 111.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KUM59100.1 - 4.9e-13 48.8 9.1 1.3e-05 24.5 0.4 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KUM59100.1 - 2.4e-09 37.5 0.2 0.12 12.3 0.0 4.2 3 1 0 4 4 4 2 AAA domain AAA_29 PF13555.1 KUM59100.1 - 2.5e-08 33.3 0.6 0.0011 18.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 KUM59100.1 - 4.3e-07 28.8 4.1 0.0025 16.4 0.2 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class DUF258 PF03193.11 KUM59100.1 - 4.8e-06 25.8 0.0 0.062 12.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KUM59100.1 - 8.8e-05 22.5 5.4 0.0017 18.3 0.2 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KUM59100.1 - 0.00029 21.6 0.0 0.1 13.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KUM59100.1 - 0.0013 18.3 2.1 0.8 9.2 0.0 3.9 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.1 KUM59100.1 - 0.002 18.2 4.7 0.35 11.0 0.2 3.9 2 2 0 2 2 2 1 AAA domain DUF87 PF01935.12 KUM59100.1 - 0.0036 17.1 0.3 1.7 8.4 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 KUM59100.1 - 0.006 16.0 0.0 1.5 8.2 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family SbcCD_C PF13558.1 KUM59100.1 - 0.0084 16.0 9.8 0.67 9.9 0.1 3.8 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 KUM59100.1 - 0.014 15.7 0.4 4.9 7.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KUM59100.1 - 0.03 13.7 7.8 0.27 10.5 0.0 4.3 4 1 1 5 5 5 0 AAA domain Zeta_toxin PF06414.7 KUM59100.1 - 0.034 13.2 0.7 0.48 9.4 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin Nuc_deoxyrib_tr PF05014.10 KUM59100.1 - 0.055 13.3 0.3 0.4 10.5 0.0 2.4 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase AAA_10 PF12846.2 KUM59100.1 - 0.055 12.8 5.3 0.21 10.9 0.0 3.3 3 1 0 4 4 4 0 AAA-like domain AAA_18 PF13238.1 KUM59100.1 - 0.068 13.4 0.0 4.2 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KUM59100.1 - 0.12 12.2 0.3 13 5.7 0.0 2.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_5 PF07728.9 KUM59100.1 - 0.13 11.9 0.5 6.6 6.4 0.0 3.4 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AMP-binding PF00501.23 KUM59101.1 - 1e-83 281.0 0.2 1.5e-83 280.5 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KUM59101.1 - 1.5e-47 161.8 0.8 2.9e-47 160.9 0.6 1.5 1 0 0 1 1 1 1 Condensation domain Thioesterase PF00975.15 KUM59101.1 - 1.3e-17 64.7 0.3 3.7e-17 63.3 0.0 1.9 2 0 0 2 2 1 1 Thioesterase domain HxxPF_rpt PF13745.1 KUM59101.1 - 3.9e-17 62.3 1.5 1.5e-16 60.5 0.3 2.6 3 0 0 3 3 3 1 HxxPF-repeated domain Abhydrolase_6 PF12697.2 KUM59101.1 - 1.8e-12 47.6 0.3 1.3e-11 44.7 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family PP-binding PF00550.20 KUM59101.1 - 2.1e-11 43.9 0.0 3.2e-10 40.1 0.0 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_26 PF13659.1 KUM59101.1 - 8.9e-09 35.4 0.0 2.7e-05 24.1 0.0 3.0 3 0 0 3 3 3 2 Methyltransferase domain Abhydrolase_5 PF12695.2 KUM59101.1 - 1.1e-08 34.9 0.0 3.4e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family AMP-binding_C PF13193.1 KUM59101.1 - 2.5e-06 28.3 0.1 0.063 14.2 0.0 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Methyltransf_31 PF13847.1 KUM59101.1 - 0.00097 18.7 0.0 0.0041 16.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM59101.1 - 0.006 16.3 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_3 PF07859.8 KUM59101.1 - 0.015 14.8 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Methyltransf_18 PF12847.2 KUM59101.1 - 0.036 14.6 0.0 0.51 10.9 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 KUM59101.1 - 0.11 12.8 0.0 0.35 11.2 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain DSHCT PF08148.7 KUM59102.1 - 4.9e-61 205.1 0.9 9.9e-61 204.1 0.6 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KUM59102.1 - 9.7e-20 70.7 0.0 2.2e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM59102.1 - 1.5e-06 27.9 0.0 4.1e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KUM59102.1 - 0.0053 16.5 0.0 0.068 13.0 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit BRCA2 PF00634.13 KUM59102.1 - 0.0083 15.3 0.3 0.018 14.2 0.2 1.6 1 0 0 1 1 1 1 BRCA2 repeat IBN_N PF03810.14 KUM59103.1 - 1.6e-16 59.9 0.2 4.3e-12 45.7 0.0 4.6 4 0 0 4 4 4 2 Importin-beta N-terminal domain Cse1 PF08506.5 KUM59103.1 - 6.5e-10 38.1 0.1 1.2e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.7 KUM59103.1 - 2.3e-05 24.3 0.9 0.0044 16.9 0.0 3.3 3 1 0 3 3 3 1 Exportin 1-like protein HEAT_2 PF13646.1 KUM59103.1 - 0.00017 21.8 0.1 0.085 13.1 0.0 3.2 2 1 0 2 2 2 1 HEAT repeats DUF2435 PF10363.4 KUM59103.1 - 0.01 15.7 0.7 0.038 13.8 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) SDA1 PF05285.7 KUM59103.1 - 3 7.0 11.3 5.1 6.2 7.8 1.2 1 0 0 1 1 1 0 SDA1 DUF4611 PF15387.1 KUM59103.1 - 10 6.3 14.5 0.085 13.0 1.3 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4611) RRM_1 PF00076.17 KUM59104.1 - 6.1e-09 35.3 0.0 1.7e-08 33.9 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM59104.1 - 4.7e-07 29.6 0.0 9.8e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KUM59104.1 - 6.2e-07 29.0 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DegS PF05384.6 KUM59105.1 - 0.016 14.4 4.0 0.032 13.4 0.7 2.2 2 0 0 2 2 2 0 Sensor protein DegS DUF2046 PF09755.4 KUM59105.1 - 0.042 12.7 3.2 0.59 8.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Rho_Binding PF08912.6 KUM59105.1 - 0.084 13.1 2.4 0.38 11.0 0.5 2.1 2 0 0 2 2 2 0 Rho Binding bZIP_2 PF07716.10 KUM59105.1 - 0.093 12.5 7.9 0.097 12.5 0.8 2.4 2 0 0 2 2 2 0 Basic region leucine zipper SPX PF03105.14 KUM59105.1 - 0.1 12.3 5.9 0.1 12.3 2.5 1.8 1 1 0 1 1 1 0 SPX domain SlyX PF04102.7 KUM59105.1 - 0.33 11.3 5.2 12 6.3 1.0 2.6 2 0 0 2 2 2 0 SlyX Striatin PF08232.7 KUM59105.1 - 0.33 11.2 6.7 1.4 9.2 0.7 2.3 2 0 0 2 2 2 0 Striatin family IncA PF04156.9 KUM59105.1 - 0.38 10.3 3.1 5.5 6.5 0.3 2.1 2 0 0 2 2 2 0 IncA protein FlaC_arch PF05377.6 KUM59105.1 - 0.48 10.3 1.9 0.72 9.7 0.1 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) CENP-F_N PF10481.4 KUM59105.1 - 1.6 7.9 10.8 0.2 11.0 0.7 2.2 1 1 1 2 2 2 0 Cenp-F N-terminal domain CCDC14 PF15254.1 KUM59105.1 - 3.7 5.7 14.7 0.023 13.1 1.1 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 14 DivIC PF04977.10 KUM59105.1 - 6 6.4 5.6 3.5 7.1 1.1 2.1 2 0 0 2 2 2 0 Septum formation initiator SET PF00856.23 KUM59106.1 - 0.038 14.3 0.0 0.091 13.0 0.0 1.5 1 1 0 1 1 1 0 SET domain DAO PF01266.19 KUM59107.1 - 1.2e-21 77.0 0.0 2e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase AMP-binding PF00501.23 KUM59109.1 - 1.9e-72 243.9 0.0 2.8e-72 243.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Aminotran_5 PF00266.14 KUM59109.1 - 1.7e-45 155.3 0.0 2.8e-45 154.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V NAD_binding_4 PF07993.7 KUM59109.1 - 1.6e-35 122.2 0.0 2.7e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 KUM59109.1 - 2.7e-07 30.7 0.1 9.9e-07 28.9 0.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 KUM59109.1 - 3.9e-07 29.7 0.0 8e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 KUM59109.1 - 2.5e-05 25.1 0.0 8.7e-05 23.3 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cys_Met_Meta_PP PF01053.15 KUM59109.1 - 0.00063 18.1 0.0 0.0018 16.6 0.0 1.6 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme 3Beta_HSD PF01073.14 KUM59109.1 - 0.048 12.3 0.3 1.4 7.5 0.1 2.7 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KUM59109.1 - 0.065 13.2 0.0 3.7 7.5 0.0 2.4 2 0 0 2 2 2 0 NADH(P)-binding ATP-grasp_4 PF13535.1 KUM59111.1 - 3.6e-22 78.9 0.0 3.3e-20 72.5 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KUM59111.1 - 6.9e-07 28.3 0.0 0.0037 16.0 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KUM59111.1 - 0.00011 21.6 0.0 0.00038 19.9 0.0 1.8 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 KUM59111.1 - 0.0013 18.6 0.0 0.033 14.0 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain GSH-S_ATP PF02955.11 KUM59111.1 - 0.23 10.5 0.0 0.45 9.6 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain LOH1CR12 PF10158.4 KUM59112.1 - 0.018 14.7 0.5 6.2 6.6 0.0 2.9 3 0 0 3 3 3 0 Tumour suppressor protein Complex1_LYR_2 PF13233.1 KUM59112.1 - 0.097 13.1 4.4 3.6 8.1 0.5 3.1 3 1 0 3 3 3 0 Complex1_LYR-like Glyco_hydro_16 PF00722.16 KUM59113.1 - 1.8e-11 43.6 0.0 1e-10 41.2 0.0 2.0 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 PHO4 PF01384.15 KUM59114.1 - 2.7e-114 381.1 12.1 3.1e-114 380.9 8.4 1.0 1 0 0 1 1 1 1 Phosphate transporter family PgaD PF13994.1 KUM59114.1 - 0.53 9.7 4.7 0.56 9.6 1.9 2.1 1 1 1 2 2 2 0 PgaD-like protein HLH PF00010.21 KUM59115.1 - 1.2e-07 31.3 0.1 2e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF904 PF06005.7 KUM59115.1 - 0.027 14.7 0.7 0.067 13.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF3509 PF12021.3 KUM59115.1 - 0.099 12.3 0.5 0.24 11.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3509) HisKA PF00512.20 KUM59115.1 - 0.12 12.4 1.3 0.53 10.3 0.9 2.0 1 1 0 1 1 1 0 His Kinase A (phospho-acceptor) domain Aminotran_5 PF00266.14 KUM59117.1 - 1.4e-26 93.1 0.0 1.8e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 KUM59117.1 - 0.0007 19.4 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 B12 binding domain Metallophos_2 PF12850.2 KUM59118.1 - 1.2e-14 54.4 0.0 1.5e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain GMC_oxred_N PF00732.14 KUM59119.1 - 3.6e-41 141.2 0.0 5.3e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KUM59119.1 - 3.8e-31 108.3 0.0 7.4e-31 107.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Bin3 PF06859.7 KUM59120.1 - 6.9e-28 96.8 0.0 9.8e-28 96.3 0.0 1.2 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_23 PF13489.1 KUM59120.1 - 5.8e-13 48.8 0.0 8.3e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM59120.1 - 2.3e-12 47.4 0.0 4.1e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM59120.1 - 7.2e-10 38.6 0.0 9e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM59120.1 - 8.6e-08 32.5 0.0 1.7e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM59120.1 - 3.4e-07 30.6 0.0 6e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KUM59120.1 - 6.4e-07 29.4 0.2 2e-06 27.8 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM59120.1 - 1.3e-05 25.5 0.0 2.3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KUM59120.1 - 4.6e-05 22.8 0.0 0.00012 21.5 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase small domain PrmA PF06325.8 KUM59120.1 - 0.00063 18.9 0.1 0.0011 18.2 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) FmrO PF07091.6 KUM59120.1 - 0.012 14.6 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) MFS_1 PF07690.11 KUM59121.1 - 1.4e-21 76.6 57.9 8e-20 70.8 36.1 3.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KUM59121.1 - 3.6e-10 38.6 10.6 7.1e-10 37.7 7.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KUM59121.1 - 2e-05 23.3 9.7 2e-05 23.3 6.7 3.4 1 1 0 3 3 3 2 Sugar (and other) transporter HHH PF00633.18 KUM59122.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF202 PF02656.10 KUM59124.1 - 2.8e-12 46.6 6.9 3.3e-12 46.4 2.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2207 PF09972.4 KUM59124.1 - 0.088 11.3 1.0 0.094 11.2 0.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4234 PF14018.1 KUM59124.1 - 0.089 12.5 0.7 0.12 12.1 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) DUF4131 PF13567.1 KUM59124.1 - 2.9 7.2 6.0 2.3 7.5 2.5 2.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) Ank_2 PF12796.2 KUM59125.1 - 3.3e-27 94.6 0.2 4.1e-09 36.6 0.0 3.8 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KUM59125.1 - 4.4e-20 70.4 2.3 0.0011 18.6 0.0 7.3 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.1 KUM59125.1 - 1.8e-15 55.4 0.1 0.07 13.4 0.0 6.7 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 KUM59125.1 - 1.9e-12 46.9 3.4 0.026 14.7 0.1 6.9 3 2 3 7 7 7 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KUM59125.1 - 9.9e-12 45.0 0.2 0.00069 20.0 0.0 5.3 3 3 3 6 6 6 4 Ankyrin repeats (many copies) F-box-like PF12937.2 KUM59125.1 - 0.00077 19.1 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 F-box-like Fungal_trans_2 PF11951.3 KUM59126.1 - 9.8e-05 21.1 0.3 0.00013 20.6 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_20 PF14561.1 KUM59126.1 - 0.15 12.1 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat GDA1_CD39 PF01150.12 KUM59127.1 - 1.4e-96 323.6 0.0 1.9e-96 323.2 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF4598 PF15370.1 KUM59128.1 - 3.9e-42 143.0 4.6 3.9e-42 143.0 3.2 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4598) Fungal_trans_2 PF11951.3 KUM59129.1 - 1.9e-42 145.2 1.3 2.4e-42 144.9 0.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM59129.1 - 9.4e-08 31.8 8.9 1.7e-07 31.0 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KUM59130.1 - 1.2e-26 93.6 1.8 1.7e-26 93.1 1.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM59130.1 - 1.5e-15 57.6 0.0 1.8e-15 57.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM59130.1 - 1.3e-09 37.9 1.3 1.9e-09 37.4 0.9 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KUM59130.1 - 0.00033 20.3 0.3 0.00062 19.4 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 KUM59130.1 - 0.00056 19.4 0.1 0.001 18.5 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 KUM59130.1 - 0.0021 17.1 0.7 0.0053 15.8 0.5 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 KUM59130.1 - 0.0039 17.2 2.1 0.04 13.9 1.3 2.3 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KUM59130.1 - 0.024 13.6 0.3 0.036 13.0 0.2 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 KUM59130.1 - 0.058 12.2 0.1 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pellino PF04710.9 KUM59130.1 - 0.076 11.6 0.0 0.096 11.3 0.0 1.1 1 0 0 1 1 1 0 Pellino Aldedh PF00171.17 KUM59131.1 - 9.1e-134 446.2 0.0 1e-133 446.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KUM59131.1 - 0.0004 19.2 0.2 0.0022 16.7 0.1 2.2 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KUM59131.1 - 0.0018 17.5 0.3 0.0061 15.8 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) MFS_1 PF07690.11 KUM59132.1 - 8.2e-46 156.3 23.3 8.2e-46 156.3 16.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM59132.1 - 5e-20 71.5 7.8 6.9e-20 71.0 5.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KUM59132.1 - 1e-06 27.2 1.6 1.8e-06 26.4 1.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 KUM59132.1 - 0.0059 14.7 0.1 0.056 11.5 0.1 2.4 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 KUM59132.1 - 0.4 8.7 4.6 0.75 7.8 3.2 1.4 1 0 0 1 1 1 0 Transmembrane secretion effector Sugar_tr PF00083.19 KUM59133.1 - 2.4e-109 365.9 28.6 2.9e-109 365.6 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM59133.1 - 1.8e-18 66.4 39.7 5.2e-12 45.1 11.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_S6 PF01250.12 KUM59134.1 - 1.9e-07 30.8 0.0 2.5e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 FlaC_arch PF05377.6 KUM59135.1 - 0.12 12.2 0.5 0.16 11.9 0.4 1.2 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) zf-rbx1 PF12678.2 KUM59136.1 - 2.7e-09 37.0 0.6 5.1e-09 36.1 0.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KUM59136.1 - 1.1e-08 34.7 9.8 2.3e-07 30.5 6.8 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KUM59136.1 - 9.4e-07 28.4 0.7 1.6e-06 27.6 0.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KUM59136.1 - 1.4e-06 27.9 1.8 4.3e-06 26.3 1.3 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KUM59136.1 - 1.5e-05 24.5 5.0 5.9e-05 22.6 3.5 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KUM59136.1 - 0.00013 21.8 2.4 0.00013 21.8 1.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KUM59136.1 - 0.0068 16.2 1.1 0.019 14.8 0.8 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PQ-loop PF04193.9 KUM59136.1 - 0.013 15.0 2.9 0.44 10.1 0.2 2.9 2 0 0 2 2 2 0 PQ loop repeat DUF2921 PF11145.3 KUM59136.1 - 0.19 9.4 0.5 0.33 8.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) zf-RING_UBOX PF13445.1 KUM59136.1 - 0.44 10.2 3.8 0.46 10.2 0.7 2.4 1 1 1 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.3 KUM59136.1 - 2.5 8.1 5.1 2.7 8.0 1.9 2.1 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.2 KUM59136.1 - 8.1 6.5 5.8 1.4 9.0 1.0 1.9 2 0 0 2 2 2 0 RING-variant domain COMPASS-Shg1 PF05205.7 KUM59137.1 - 2.8e-31 107.9 0.1 7.1e-31 106.6 0.1 1.7 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 Gln-synt_C PF00120.19 KUM59139.1 - 1.6e-56 191.3 0.0 2.1e-56 190.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain GATase PF00117.23 KUM59140.1 - 1.2e-14 54.1 0.0 1.7e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KUM59140.1 - 1.4e-05 24.6 0.0 0.00018 21.0 0.0 2.6 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.9 KUM59140.1 - 0.00031 20.3 0.0 0.0005 19.6 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DUF4066 PF13278.1 KUM59140.1 - 0.013 14.7 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Putative amidotransferase SNO PF01174.14 KUM59140.1 - 0.032 13.8 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Lipase_GDSL PF00657.17 KUM59141.1 - 1.8e-13 50.8 0.3 2.3e-13 50.5 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Fungal_trans PF04082.13 KUM59142.1 - 9.3e-08 31.2 0.3 2.7e-07 29.7 0.0 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain IF3_C PF00707.17 KUM59143.1 - 1.2e-14 53.7 0.7 2.3e-14 52.9 0.5 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.11 KUM59143.1 - 2.3e-07 30.6 0.0 4.6e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.1 KUM59143.1 - 7.1e-05 22.2 2.9 0.00011 21.6 2.0 1.3 1 0 0 1 1 1 1 Mitochondrial translation initiation factor GTP_EFTU PF00009.22 KUM59144.1 - 2.3e-60 203.2 0.2 3.3e-60 202.7 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KUM59144.1 - 4.7e-22 78.0 0.0 9.8e-22 76.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KUM59144.1 - 2.3e-17 62.8 1.8 2.3e-17 62.8 1.3 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KUM59144.1 - 1.1e-05 25.3 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 KUM59144.1 - 0.002 17.7 0.1 0.0056 16.2 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 KUM59144.1 - 0.0056 17.1 0.0 0.0098 16.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 KUM59144.1 - 0.065 12.7 0.1 5.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Cation_efflux PF01545.16 KUM59146.1 - 2.1e-31 109.0 7.4 2.7e-31 108.7 5.1 1.1 1 0 0 1 1 1 1 Cation efflux family RHD3 PF05879.7 KUM59147.1 - 0 1058.9 0.0 0 1058.6 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 KUM59147.1 - 3e-07 29.7 0.2 5e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 KUM59147.1 - 1.4e-06 28.2 0.0 3.3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KUM59147.1 - 0.00077 19.3 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 KUM59147.1 - 0.0009 19.2 0.0 0.0031 17.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 KUM59147.1 - 0.0013 19.1 0.0 0.0027 18.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Cyclase PF04199.8 KUM59148.1 - 1.4e-06 28.1 0.0 2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Cupin_3 PF05899.7 KUM59148.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) GCV_H PF01597.14 KUM59149.1 - 4.6e-36 123.1 2.1 5.7e-36 122.8 1.4 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 KUM59149.1 - 0.088 12.4 0.9 1.3 8.6 0.1 2.2 1 1 1 2 2 2 0 Biotin-requiring enzyme Oxidored_FMN PF00724.15 KUM59152.1 - 1.4e-95 320.2 0.0 1.6e-95 319.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family GRDA PF04723.9 KUM59152.1 - 0.0022 17.6 0.0 0.0039 16.9 0.0 1.3 1 0 0 1 1 1 1 Glycine reductase complex selenoprotein A Grp1_Fun34_YaaH PF01184.14 KUM59153.1 - 7.5e-86 286.7 16.5 9.2e-86 286.4 11.4 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Fungal_trans_2 PF11951.3 KUM59154.1 - 1.7e-11 43.3 0.0 6.9e-11 41.3 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_71 PF03659.9 KUM59155.1 - 7.2e-58 195.8 5.6 8.8e-58 195.5 3.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.1 KUM59155.1 - 0.022 14.4 0.4 0.061 13.0 0.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) EIF_2_alpha PF07541.7 KUM59155.1 - 0.098 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit Memo PF01875.12 KUM59156.1 - 1.2e-37 129.3 0.0 1.5e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein MFS_1 PF07690.11 KUM59157.1 - 3.6e-36 124.6 22.2 5e-36 124.1 15.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM59157.1 - 2.3e-13 49.5 6.0 2.3e-13 49.5 4.1 1.9 2 1 1 3 3 3 1 Sugar (and other) transporter WD40 PF00400.27 KUM59159.1 - 1.1e-30 104.3 9.9 1.2e-07 31.2 0.0 8.0 8 0 0 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 KUM59159.1 - 6.9e-06 25.9 0.5 0.022 14.4 0.0 2.8 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.5 KUM59159.1 - 9.2e-05 21.8 2.3 0.00021 20.7 0.1 2.8 2 0 0 2 2 2 1 HIRA B motif PD40 PF07676.7 KUM59159.1 - 0.018 14.6 2.3 6.3 6.5 0.0 3.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Glyco_transf_20 PF00982.16 KUM59160.1 - 2.6e-142 474.6 0.0 5.3e-142 473.6 0.0 1.4 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KUM59160.1 - 4.9e-27 94.3 0.0 7.7e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase T5orf172 PF10544.4 KUM59161.1 - 1.5e-14 54.1 0.9 3.7e-14 52.9 0.6 1.6 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.1 KUM59161.1 - 2.7e-10 40.5 2.6 5.3e-10 39.6 1.8 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 GIY-YIG PF01541.19 KUM59161.1 - 0.028 14.7 0.2 0.063 13.6 0.1 1.7 1 0 0 1 1 1 0 GIY-YIG catalytic domain Glyco_hydro_71 PF03659.9 KUM59162.1 - 1.4e-31 109.4 0.0 1.6e-31 109.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Transglut_core PF01841.14 KUM59164.1 - 7.9e-14 51.8 2.4 1.8e-13 50.6 1.7 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.10 KUM59164.1 - 1.1e-13 50.8 6.0 1.8e-13 50.0 4.2 1.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain DUF605 PF04652.11 KUM59164.1 - 0.17 11.2 7.6 0.25 10.6 5.3 1.2 1 0 0 1 1 1 0 Vta1 like Presenilin PF01080.12 KUM59166.1 - 0.64 8.7 3.2 0.8 8.4 2.2 1.1 1 0 0 1 1 1 0 Presenilin DASH_Spc34 PF08657.5 KUM59167.1 - 4.8e-67 226.3 3.4 1.2e-65 221.7 2.3 2.0 1 1 0 1 1 1 1 DASH complex subunit Spc34 IncA PF04156.9 KUM59167.1 - 0.0094 15.5 0.6 0.024 14.2 0.4 1.6 1 1 0 1 1 1 1 IncA protein DASH_Spc19 PF08287.6 KUM59167.1 - 0.044 13.3 0.1 0.073 12.6 0.1 1.3 1 0 0 1 1 1 0 Spc19 Spectrin PF00435.16 KUM59167.1 - 0.053 13.8 0.2 6.8 7.0 0.0 2.5 3 0 0 3 3 3 0 Spectrin repeat DUF465 PF04325.8 KUM59167.1 - 0.063 12.9 0.8 0.17 11.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF465) EndoU_bacteria PF14436.1 KUM59167.1 - 0.082 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial EndoU nuclease Prefoldin_2 PF01920.15 KUM59167.1 - 0.12 12.2 0.3 7.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Prefoldin subunit Med9 PF07544.8 KUM59167.1 - 0.36 10.5 1.9 3.4 7.4 0.4 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 ATP-sulfurylase PF01747.12 KUM59168.1 - 4.8e-87 290.7 0.0 6.7e-87 290.3 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 KUM59168.1 - 4.4e-59 198.6 0.0 6.7e-59 198.0 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 KUM59168.1 - 3.5e-51 172.7 0.0 6.3e-51 171.9 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain KTI12 PF08433.5 KUM59168.1 - 0.057 12.6 0.0 0.089 11.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 hEGF PF12661.2 KUM59169.1 - 0.062 13.4 1.8 0.13 12.3 1.2 1.6 1 0 0 1 1 1 0 Human growth factor-like EGF OppC_N PF12911.2 KUM59169.1 - 0.2 11.0 1.3 0.8 9.1 0.6 2.1 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C EGF_2 PF07974.8 KUM59169.1 - 2.3 8.4 12.6 4.4 7.5 8.8 1.5 1 0 0 1 1 1 0 EGF-like domain Bcl-2_BAD PF10514.4 KUM59170.1 - 0.0078 16.1 0.1 0.0089 16.0 0.0 1.1 1 0 0 1 1 1 1 Pro-apoptotic Bcl-2 protein, BAD Complex1_LYR_1 PF13232.1 KUM59171.1 - 5.7e-16 58.4 5.5 9.1e-16 57.8 3.8 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KUM59171.1 - 4.3e-14 52.0 5.0 4.3e-14 52.0 3.5 1.5 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 KUM59171.1 - 0.015 15.7 2.0 0.02 15.3 1.4 1.1 1 0 0 1 1 1 0 Complex1_LYR-like IATP PF04568.7 KUM59171.1 - 0.74 9.8 5.0 0.19 11.7 1.0 1.8 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP SET PF00856.23 KUM59172.1 - 4.8e-16 59.4 0.4 4.8e-16 59.4 0.3 3.8 3 3 0 3 3 3 1 SET domain polyprenyl_synt PF00348.12 KUM59173.1 - 3.5e-51 173.5 0.0 5.6e-48 163.0 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase HMG_box PF00505.14 KUM59174.1 - 8.1e-20 70.8 0.0 1.2e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KUM59174.1 - 0.0018 18.5 0.0 0.003 17.8 0.0 1.3 1 0 0 1 1 1 1 HMG-box domain Exo_endo_phos_2 PF14529.1 KUM59175.1 - 8.4e-16 57.6 0.2 2.3e-15 56.2 0.0 1.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 KUM59175.1 - 1.1e-10 41.8 0.0 2.1e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.7 KUM59175.1 - 0.00012 21.9 0.2 0.00031 20.5 0.1 1.7 1 0 0 1 1 1 1 GRF zinc finger COX6A PF02046.10 KUM59176.1 - 1.4e-45 153.9 1.6 1.8e-45 153.5 1.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa PAPS_reduct PF01507.14 KUM59177.1 - 0.039 13.7 0.1 0.062 13.1 0.1 1.2 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Rpn3_C PF08375.6 KUM59178.1 - 2.5e-25 88.6 0.6 8.6e-25 86.9 0.4 2.0 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 KUM59178.1 - 4.1e-19 68.8 0.3 1.9e-18 66.6 0.0 2.2 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 KUM59178.1 - 0.00047 19.9 0.1 0.02 14.6 0.0 2.4 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 MSA_2 PF00985.12 KUM59178.1 - 0.98 9.5 17.0 1.8 8.6 11.8 1.3 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family DUF2404 PF10296.4 KUM59179.1 - 3.6e-30 103.9 0.0 7e-30 103.0 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) ANTH PF07651.11 KUM59180.1 - 1.2e-78 263.7 0.0 1.2e-78 263.7 0.0 2.7 2 1 1 3 3 3 1 ANTH domain I_LWEQ PF01608.12 KUM59180.1 - 2.2e-64 215.9 4.2 2.2e-64 215.9 2.9 6.0 4 2 1 6 6 6 1 I/LWEQ domain ENTH PF01417.15 KUM59180.1 - 0.00019 21.2 0.0 0.001 18.9 0.0 2.3 1 0 0 1 1 1 1 ENTH domain NFRKB_winged PF14465.1 KUM59180.1 - 0.23 11.3 3.2 3.5 7.5 0.3 3.7 3 1 1 4 4 4 0 NFRKB Winged Helix-like SpoIISA_toxin PF14171.1 KUM59180.1 - 2.6 7.2 5.6 7.1 5.8 3.9 1.7 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system PARP PF00644.15 KUM59181.1 - 2.2e-10 40.3 0.2 5.6e-10 38.9 0.1 1.7 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 KUM59181.1 - 3.2e-07 29.8 0.0 7.1e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Seipin PF06775.9 KUM59183.1 - 5.9e-63 211.9 0.0 7.9e-63 211.5 0.0 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) TTL PF03133.10 KUM59184.1 - 1.1e-56 191.8 0.0 1.8e-56 191.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 KUM59184.1 - 2.7e-43 147.5 0.0 4.1e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.1 KUM59184.1 - 6.5e-06 25.1 0.0 0.00036 19.4 0.0 2.2 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 KUM59184.1 - 1.3e-05 25.0 0.1 0.0015 18.2 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain Glyco_trans_4_4 PF13579.1 KUM59184.1 - 0.064 13.4 0.3 0.21 11.7 0.2 2.0 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Dala_Dala_lig_C PF07478.8 KUM59184.1 - 0.075 12.4 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Not1 PF04054.10 KUM59186.1 - 4.3e-139 463.5 0.3 9.3e-139 462.4 0.2 1.5 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 KUM59186.1 - 1.4e-51 173.9 1.0 3.1e-51 172.9 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) DUF3696 PF12476.3 KUM59186.1 - 0.038 13.9 0.1 0.33 10.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3696) DUF3169 PF11368.3 KUM59187.1 - 0.02 14.0 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF1482 PF07358.6 KUM59187.1 - 0.11 12.1 0.0 0.31 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1482) Ndc80_HEC PF03801.8 KUM59189.1 - 4.8e-61 204.8 0.0 9.9e-61 203.8 0.0 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family Filament PF00038.16 KUM59189.1 - 0.00036 20.0 21.9 0.00036 20.0 15.2 2.5 2 1 0 2 2 2 2 Intermediate filament protein CENP-F_leu_zip PF10473.4 KUM59189.1 - 0.0006 19.6 9.8 0.0006 19.6 6.8 4.3 2 2 2 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 KUM59189.1 - 0.0092 15.5 12.5 0.0092 15.5 8.7 4.0 2 2 2 4 4 4 1 IncA protein Reo_sigmaC PF04582.7 KUM59189.1 - 0.41 9.7 4.2 0.24 10.5 0.3 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Adenylsucc_synt PF00709.16 KUM59189.1 - 1.5 7.3 13.6 5 5.6 0.3 2.3 2 0 0 2 2 2 0 Adenylosuccinate synthetase NPV_P10 PF05531.7 KUM59189.1 - 6.6 7.0 14.7 15 5.8 0.2 4.3 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein PrpF PF04303.8 KUM59190.1 - 5.7e-104 347.7 0.4 6.7e-104 347.5 0.3 1.0 1 0 0 1 1 1 1 PrpF protein Fungal_trans PF04082.13 KUM59192.1 - 3e-21 75.4 0.0 4.7e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pex14_N PF04695.8 KUM59193.1 - 0.0013 18.7 0.6 0.0013 18.7 0.4 3.7 3 2 0 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Baculo_PEP_C PF04513.7 KUM59193.1 - 0.0021 17.8 1.8 0.024 14.4 1.3 2.3 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus BID PF06393.6 KUM59193.1 - 0.015 14.6 0.1 0.027 13.8 0.1 1.5 1 0 0 1 1 1 0 BH3 interacting domain (BID) DUF3584 PF12128.3 KUM59193.1 - 0.016 12.6 3.8 0.021 12.2 2.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) zf-C4H2 PF10146.4 KUM59193.1 - 0.029 14.4 4.0 0.061 13.3 2.8 1.7 1 1 0 1 1 1 0 Zinc finger-containing protein Cytochrom_B562 PF07361.6 KUM59193.1 - 0.043 14.2 1.0 0.089 13.2 0.5 1.7 1 1 0 1 1 1 0 Cytochrome b562 CR6_interact PF10147.4 KUM59193.1 - 0.074 12.3 0.3 0.13 11.5 0.2 1.5 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 TRADD_N PF09034.5 KUM59193.1 - 0.089 12.7 0.6 0.13 12.2 0.4 1.2 1 0 0 1 1 1 0 TRADD, N-terminal domain DUF244 PF03112.9 KUM59193.1 - 0.21 11.0 0.6 0.35 10.4 0.3 1.4 1 1 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF ERM PF00769.14 KUM59193.1 - 0.27 10.7 6.1 0.44 10.0 4.2 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family GAS PF13851.1 KUM59193.1 - 0.62 9.2 4.1 1.3 8.2 2.8 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 KUM59193.1 - 1.3 8.6 6.3 3 7.3 4.4 1.5 1 1 0 1 1 1 0 IncA protein DUF4164 PF13747.1 KUM59193.1 - 5.1 7.2 9.9 1.4 9.0 4.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) PT PF04886.7 KUM59194.1 - 0.62 9.4 45.1 1.1 8.6 11.5 4.2 3 1 0 3 3 3 0 PT repeat DUF605 PF04652.11 KUM59194.1 - 8 5.7 6.0 10 5.3 4.1 1.1 1 0 0 1 1 1 0 Vta1 like HNH_2 PF13391.1 KUM59197.1 - 4e-08 32.9 0.0 1.3e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 HNH endonuclease AHH PF14412.1 KUM59197.1 - 0.074 13.0 0.0 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH DUF2451 PF10474.4 KUM59197.1 - 0.13 12.0 0.1 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) Saccharop_dh PF03435.13 KUM59198.1 - 4.4e-103 345.2 0.0 1.3e-102 343.6 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KUM59198.1 - 3.4e-09 36.8 0.2 1.1e-08 35.2 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 KUM59198.1 - 0.013 14.9 0.6 0.25 10.7 0.0 2.7 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 KUM59198.1 - 0.013 15.3 0.0 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.1 KUM59198.1 - 0.014 15.6 0.2 0.028 14.6 0.2 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ThiF PF00899.16 KUM59198.1 - 0.08 12.7 1.1 2.1 8.1 0.2 2.6 2 1 1 3 3 3 0 ThiF family NmrA PF05368.8 KUM59198.1 - 0.12 11.6 0.1 0.2 10.8 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family Sugar_tr PF00083.19 KUM59199.1 - 8.4e-84 281.7 28.9 1e-83 281.4 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM59199.1 - 3.7e-19 68.6 21.5 3.7e-19 68.6 14.9 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily p450 PF00067.17 KUM59201.1 - 7e-25 87.4 0.0 1.2e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 5-FTHF_cyc-lig PF01812.15 KUM59202.1 - 1.7e-39 135.5 0.0 1.9e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Amidohydro_2 PF04909.9 KUM59203.1 - 6.7e-42 143.9 0.5 9.2e-42 143.4 0.3 1.3 1 1 0 1 1 1 1 Amidohydrolase Acid_PPase PF12689.2 KUM59203.1 - 0.019 14.5 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 Acid Phosphatase Trypan_PARP PF05887.6 KUM59204.1 - 0.43 10.3 8.5 0.72 9.6 5.9 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RINGv PF12906.2 KUM59205.1 - 9.1e-09 35.2 5.3 1.2e-08 34.8 1.0 2.2 2 0 0 2 2 2 1 RING-variant domain zf-RanBP PF00641.13 KUM59205.1 - 0.056 12.5 0.1 0.13 11.3 0.0 1.6 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others zf-BED PF02892.10 KUM59205.1 - 0.056 13.2 0.3 0.056 13.2 0.2 1.7 2 0 0 2 2 2 0 BED zinc finger zf-RING_2 PF13639.1 KUM59205.1 - 0.11 12.3 9.2 0.94 9.3 6.4 2.1 1 1 0 1 1 1 0 Ring finger domain PHD PF00628.24 KUM59205.1 - 0.64 9.7 5.1 0.25 11.0 1.6 1.7 2 0 0 2 2 2 0 PHD-finger DUF2752 PF10825.3 KUM59205.1 - 1.5 8.8 5.3 1.1 9.3 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) DUF1206 PF06724.6 KUM59205.1 - 2 8.1 9.6 1.1 9.1 2.7 2.8 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1206) Proteasome PF00227.21 KUM59206.1 - 2.2e-56 190.1 0.0 1.3e-31 109.3 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 KUM59206.1 - 1.7e-11 43.2 0.3 4.1e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_S13 PF02113.10 KUM59206.1 - 0.043 12.3 0.1 0.6 8.5 0.0 2.0 2 0 0 2 2 2 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family Methyltransf_2 PF00891.13 KUM59206.1 - 0.17 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase AAA_25 PF13481.1 KUM59208.1 - 5.9e-08 32.3 0.0 3e-07 30.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain Rad51 PF08423.6 KUM59208.1 - 1e-07 31.1 0.0 0.002 17.0 0.0 2.8 2 1 0 2 2 2 2 Rad51 RecA PF00154.16 KUM59208.1 - 9.8e-07 28.1 0.0 2.7e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein KaiC PF06745.8 KUM59208.1 - 2.5e-05 23.4 0.0 5.6e-05 22.3 0.0 1.5 2 0 0 2 2 2 1 KaiC IstB_IS21 PF01695.12 KUM59208.1 - 0.00053 19.4 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 KUM59208.1 - 0.0016 18.1 0.1 0.017 14.8 0.1 2.4 2 0 0 2 2 2 1 Part of AAA domain PhoH PF02562.11 KUM59208.1 - 0.0024 17.1 0.0 0.0043 16.3 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_10 PF12846.2 KUM59208.1 - 0.0042 16.5 0.1 0.061 12.7 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain AAA PF00004.24 KUM59208.1 - 0.02 15.0 0.0 0.039 14.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KUM59208.1 - 0.023 15.5 0.1 0.3 11.9 0.0 2.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KUM59208.1 - 0.026 14.0 0.0 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 KUM59208.1 - 0.039 13.4 0.0 0.085 12.3 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_16 PF13191.1 KUM59208.1 - 0.049 13.6 1.1 1.1 9.1 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 KUM59208.1 - 0.053 13.8 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 ABC transporter Zot PF05707.7 KUM59208.1 - 0.06 12.7 0.0 0.16 11.4 0.0 1.8 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) MOSC PF03473.12 KUM59209.1 - 3e-17 62.3 0.0 5.3e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 KUM59209.1 - 1.7e-07 30.9 0.0 2.9e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Xan_ur_permease PF00860.15 KUM59211.1 - 1.9e-63 214.3 31.7 5.4e-63 212.7 22.0 1.6 1 1 0 1 1 1 1 Permease family FA_desaturase PF00487.19 KUM59213.1 - 2.9e-19 69.5 13.0 5.1e-19 68.7 9.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KUM59213.1 - 1.3e-16 60.1 0.1 3.4e-16 58.8 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2225 PF09986.4 KUM59213.1 - 0.034 13.6 0.0 0.079 12.4 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) MHC_I PF00129.13 KUM59214.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 Xpo1 PF08389.7 KUM59218.1 - 6.2e-27 94.3 0.4 2.4e-25 89.1 0.0 3.4 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 KUM59218.1 - 0.00013 21.7 0.1 0.00082 19.2 0.0 2.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain Fungal_trans PF04082.13 KUM59219.1 - 5e-62 209.1 0.1 6.7e-62 208.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain EF-hand_7 PF13499.1 KUM59219.1 - 2.6e-10 40.2 0.3 5e-08 32.9 0.1 2.6 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KUM59219.1 - 2.4e-06 26.9 0.6 0.1 12.5 0.0 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_9 PF14658.1 KUM59219.1 - 6.3e-06 26.0 0.0 0.043 13.7 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KUM59219.1 - 6.9e-05 21.8 0.1 0.15 11.4 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 KUM59219.1 - 0.0013 18.3 0.6 0.012 15.2 0.1 2.7 2 1 1 3 3 3 1 EF-hand domain pair zf-C2H2 PF00096.21 KUM59219.1 - 0.0019 18.4 0.9 0.0019 18.4 0.6 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KUM59219.1 - 0.002 18.3 11.9 0.0037 17.4 0.5 3.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KUM59219.1 - 0.005 17.0 6.4 0.042 14.1 1.1 2.8 2 0 0 2 2 2 1 Zinc-finger double domain Peptidase_M3 PF01432.15 KUM59220.1 - 3.4e-162 540.6 0.0 5.5e-162 539.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 SUV3_C PF12513.3 KUM59220.1 - 0.0034 16.8 0.0 0.009 15.4 0.0 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal AA_permease_2 PF13520.1 KUM59221.1 - 2.6e-58 197.5 47.0 3.2e-58 197.2 32.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM59221.1 - 1e-23 83.4 44.1 1.3e-23 83.0 30.6 1.1 1 0 0 1 1 1 1 Amino acid permease Sensor_TM1 PF13755.1 KUM59221.1 - 0.3 10.6 2.7 2.5 7.6 0.0 2.7 2 0 0 2 2 2 0 Sensor N-terminal transmembrane domain Zn_clus PF00172.13 KUM59222.1 - 3.5e-05 23.6 7.4 6.4e-05 22.7 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N_2 PF13409.1 KUM59223.1 - 5.1e-16 58.4 0.0 1.6e-15 56.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KUM59223.1 - 3.8e-10 39.5 0.0 9.7e-10 38.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KUM59223.1 - 2e-05 25.0 0.0 3.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KUM59223.1 - 0.0013 18.9 0.0 0.44 10.8 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain adh_short PF00106.20 KUM59225.1 - 5.8e-16 58.8 0.6 8.7e-16 58.2 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM59225.1 - 1.4e-11 44.6 0.1 1.7e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM59225.1 - 1.2e-09 38.0 0.1 3e-09 36.7 0.0 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KUM59225.1 - 7.6e-07 29.3 0.3 2.2e-06 27.8 0.2 1.8 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KUM59225.1 - 3.7e-05 23.1 0.1 8e-05 21.9 0.1 1.5 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 KUM59225.1 - 0.00082 19.3 0.4 0.0026 17.7 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain Epimerase PF01370.16 KUM59225.1 - 0.0011 18.4 0.0 0.0017 17.8 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KUM59225.1 - 0.0046 15.7 0.0 0.006 15.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KUM59225.1 - 0.027 13.4 0.2 0.24 10.2 0.1 2.4 1 1 0 1 1 1 0 Male sterility protein PseudoU_synth_2 PF00849.17 KUM59225.1 - 0.032 14.0 0.0 0.05 13.4 0.0 1.2 1 0 0 1 1 1 0 RNA pseudouridylate synthase Cys_Met_Meta_PP PF01053.15 KUM59226.1 - 2.2e-148 493.6 0.0 2.5e-148 493.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KUM59226.1 - 1.7e-12 47.0 1.0 3.6e-12 46.0 0.6 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 KUM59226.1 - 6e-09 35.3 0.1 9.8e-09 34.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KUM59226.1 - 3.3e-08 32.6 0.2 5.3e-08 32.0 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KUM59226.1 - 7.8e-08 31.8 0.0 1.3e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 KUM59226.1 - 7.9e-05 21.1 0.1 0.00011 20.6 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 KUM59226.1 - 0.0073 15.0 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Pyr_redox_3 PF13738.1 KUM59227.1 - 1.3e-22 80.9 0.0 4.3e-22 79.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KUM59227.1 - 2.6e-11 42.4 0.2 1.1e-08 33.7 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KUM59227.1 - 8.6e-10 38.8 0.0 1.4e-07 31.5 0.0 2.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KUM59227.1 - 1.2e-09 37.5 0.1 2e-07 30.2 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KUM59227.1 - 2e-06 27.7 0.0 1.6e-05 24.8 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KUM59227.1 - 1.6e-05 24.1 0.1 2.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KUM59227.1 - 0.00045 20.5 0.2 2.3 8.6 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KUM59227.1 - 0.00068 18.5 0.2 0.0013 17.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KUM59227.1 - 0.002 16.6 0.1 0.0053 15.2 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 KUM59227.1 - 0.0034 16.5 0.0 0.06 12.4 0.0 2.4 2 0 0 2 2 2 1 Thi4 family 2-Hacid_dh_C PF02826.14 KUM59227.1 - 0.013 14.6 0.1 0.12 11.5 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 KUM59227.1 - 0.017 14.0 0.0 0.1 11.5 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 KUM59227.1 - 0.039 12.8 0.5 0.38 9.5 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A SnoaL_2 PF12680.2 KUM59227.1 - 0.053 13.9 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 SnoaL-like domain AlaDh_PNT_C PF01262.16 KUM59227.1 - 0.065 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Citrate_synt PF00285.16 KUM59228.1 - 3.9e-101 338.3 0.0 4.7e-101 338.0 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase RRM_1 PF00076.17 KUM59229.1 - 3.7e-06 26.4 0.0 6.5e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM59229.1 - 0.00013 21.6 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM59229.1 - 0.00048 20.0 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 KUM59229.1 - 0.0011 19.1 0.0 0.0037 17.4 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase II-binding domain. Pkinase PF00069.20 KUM59230.1 - 5.9e-14 51.8 0.0 8.8e-14 51.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 KUM59230.1 - 5.8e-12 44.9 4.6 0.013 15.3 0.0 6.4 7 0 0 7 7 7 3 WD domain, G-beta repeat PD40 PF07676.7 KUM59230.1 - 5.9e-09 35.3 2.8 1.1 8.9 0.0 6.6 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat eIF2A PF08662.6 KUM59230.1 - 5e-05 23.1 0.0 0.1 12.3 0.0 2.7 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 KUM59230.1 - 0.00022 20.4 0.1 0.63 9.0 0.0 3.2 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Pkinase_Tyr PF07714.12 KUM59230.1 - 0.0041 16.2 0.0 0.0067 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DPPIV_N PF00930.16 KUM59230.1 - 0.054 12.0 0.0 7.1 5.1 0.0 3.3 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Proteasome_A_N PF10584.4 KUM59230.1 - 4.2 6.7 0.0 4.2 6.7 0.0 4.2 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature RNA_pol_Rpc82 PF05645.8 KUM59231.1 - 1.8e-24 86.6 0.0 5.8e-20 71.9 0.0 2.6 2 1 1 3 3 3 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 KUM59231.1 - 8.2e-17 60.8 2.8 1.3e-09 37.7 0.1 3.8 4 0 0 4 4 4 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 KUM59231.1 - 9.5e-05 21.8 0.3 0.00082 18.8 0.0 2.5 2 1 1 3 3 3 1 TFIIE alpha subunit HTH_27 PF13463.1 KUM59231.1 - 0.059 13.7 0.0 0.62 10.4 0.0 2.7 3 0 0 3 3 3 0 Winged helix DNA-binding domain Peptidase_M16 PF00675.15 KUM59232.1 - 9.3e-20 70.9 0.0 2.1e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KUM59232.1 - 7.2e-15 55.1 0.1 1.8e-14 53.8 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain M16C_assoc PF08367.6 KUM59232.1 - 0.0026 16.6 0.0 0.0047 15.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Bac_DNA_binding PF00216.16 KUM59232.1 - 0.18 11.8 1.4 14 5.7 0.1 2.7 2 0 0 2 2 2 0 Bacterial DNA-binding protein Septin PF00735.13 KUM59233.1 - 2.1e-14 53.2 0.0 1.1e-13 50.8 0.0 1.9 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KUM59233.1 - 0.00079 19.3 0.0 0.0019 18.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 KUM59233.1 - 0.003 17.4 0.0 0.0084 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KUM59233.1 - 0.0037 16.4 0.0 0.0076 15.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Miro PF08477.8 KUM59233.1 - 0.014 15.8 0.0 0.037 14.5 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_16 PF13191.1 KUM59233.1 - 0.018 15.0 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 KUM59233.1 - 0.021 15.1 0.0 0.045 14.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 KUM59233.1 - 0.022 14.2 0.8 0.048 13.1 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Dynamin_N PF00350.18 KUM59233.1 - 0.022 14.5 0.0 5.6 6.7 0.1 2.6 2 0 0 2 2 2 0 Dynamin family Viral_helicase1 PF01443.13 KUM59233.1 - 0.027 14.0 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.1 KUM59233.1 - 0.031 15.0 0.0 0.075 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 KUM59233.1 - 0.032 13.1 0.0 0.052 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 KUM59233.1 - 0.034 13.5 0.0 0.071 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KUM59233.1 - 0.046 13.8 0.0 0.39 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KUM59233.1 - 0.053 13.1 0.1 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 KUM59233.1 - 0.055 12.9 0.1 0.47 9.8 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 KUM59233.1 - 0.062 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 KUM59233.1 - 0.085 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 KUM59233.1 - 0.089 11.9 0.1 0.2 10.7 0.0 1.6 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 KUM59233.1 - 0.1 12.1 0.1 0.64 9.5 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation UPF0079 PF02367.12 KUM59233.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 KUM59233.1 - 0.12 11.4 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 KUM59233.1 - 0.12 11.5 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 KUM59233.1 - 0.14 11.8 0.1 0.24 11.0 0.1 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 KUM59233.1 - 0.14 11.5 0.1 0.3 10.5 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family G-alpha PF00503.15 KUM59233.1 - 0.18 10.4 0.0 0.31 9.6 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Pox_A32 PF04665.7 KUM59233.1 - 0.31 10.2 0.0 0.51 9.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein HLH PF00010.21 KUM59234.1 - 3.8e-12 45.7 2.5 7.5e-12 44.7 1.8 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Sugar_tr PF00083.19 KUM59235.1 - 9.3e-77 258.4 18.9 1.1e-76 258.3 13.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM59235.1 - 2.2e-20 72.7 36.5 1.6e-13 50.1 10.0 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 KUM59235.1 - 4.1e-05 22.1 3.0 4.1e-05 22.1 2.1 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein Mito_carr PF00153.22 KUM59236.1 - 2.3e-26 91.3 5.8 1.7e-11 43.6 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF3328 PF11807.3 KUM59237.1 - 7.5e-54 182.6 0.0 1e-53 182.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) C-C_Bond_Lyase PF15617.1 KUM59237.1 - 0.16 10.7 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 C-C_Bond_Lyase of the TIM-Barrel fold DUF2582 PF10771.4 KUM59238.1 - 0.059 13.2 0.0 0.46 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2582) DUF3754 PF12576.3 KUM59238.1 - 2.2 7.9 4.5 6.9 6.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) Transp_cyt_pur PF02133.10 KUM59239.1 - 1.9e-13 49.7 13.4 2.5e-13 49.4 9.3 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pox_A28 PF04584.9 KUM59239.1 - 1.6 8.5 4.0 4.9 7.0 2.6 1.8 2 0 0 2 2 2 0 Poxvirus A28 family Asp PF00026.18 KUM59240.1 - 2.5e-42 145.2 5.1 3e-42 144.9 3.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KUM59240.1 - 0.0002 21.3 0.2 0.0008 19.3 0.1 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KUM59240.1 - 0.0021 17.6 0.2 0.0058 16.1 0.2 1.8 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KUM59240.1 - 0.0095 16.4 0.1 0.95 10.0 0.0 2.9 2 0 0 2 2 2 1 Aspartyl protease Fungal_trans PF04082.13 KUM59241.1 - 5.6e-14 51.6 0.8 9.7e-14 50.8 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Arabinose_Iso_C PF11762.3 KUM59241.1 - 0.0066 16.0 0.7 1.3 8.6 0.0 3.3 2 1 1 3 3 3 1 L-arabinose isomerase C-terminal domain ADH_zinc_N_2 PF13602.1 KUM59242.1 - 1.2e-11 45.5 0.2 3.8e-11 43.9 0.0 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KUM59242.1 - 2.3e-11 43.3 0.3 3.9e-11 42.5 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM59242.1 - 1.1e-09 38.0 0.1 1.5e-06 27.9 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 KUM59242.1 - 0.0034 17.4 0.3 0.0064 16.5 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding Acetyltransf_3 PF13302.1 KUM59243.1 - 1.8e-24 86.5 0.0 2.1e-24 86.3 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KUM59243.1 - 8.7e-09 35.2 0.0 3.2e-08 33.4 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KUM59243.1 - 0.006 16.4 0.0 0.0074 16.1 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KUM59243.1 - 0.019 14.7 0.0 0.058 13.1 0.0 1.7 2 0 0 2 2 2 0 FR47-like protein UBN2_3 PF14244.1 KUM59244.1 - 0.0013 18.3 0.1 0.0017 17.9 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type adh_short PF00106.20 KUM59246.1 - 1.5e-27 96.5 0.1 2.6e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM59246.1 - 2.9e-19 69.8 0.1 5.8e-18 65.5 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM59246.1 - 1.9e-14 53.7 0.1 1.1e-13 51.2 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KUM59246.1 - 3.8e-06 26.4 0.0 1.8e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sugar_tr PF00083.19 KUM59247.1 - 2.5e-93 313.0 23.8 2.9e-93 312.8 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM59247.1 - 5.1e-29 101.0 37.8 2.4e-24 85.7 12.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KUM59247.1 - 7.3e-08 30.9 4.8 0.00039 18.6 1.0 2.3 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.2 KUM59247.1 - 0.00031 20.4 0.7 0.81 9.5 0.0 2.7 2 0 0 2 2 2 2 MFS_1 like family FMN_dh PF01070.13 KUM59249.1 - 6e-75 252.3 3.0 1.2e-73 248.0 2.1 2.0 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KUM59249.1 - 3.2e-06 26.3 0.1 4.7e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KUM59249.1 - 0.0003 19.7 1.0 0.00063 18.7 0.6 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KUM59249.1 - 0.0058 15.8 0.7 0.01 15.0 0.5 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 KUM59249.1 - 0.028 13.6 0.0 0.069 12.4 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein ThiG PF05690.9 KUM59249.1 - 0.029 13.4 0.1 0.66 8.9 0.1 2.2 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 KUM59249.1 - 0.034 13.1 0.0 0.12 11.2 0.0 1.8 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Ldh_1_C PF02866.13 KUM59249.1 - 0.087 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain Sugar_tr PF00083.19 KUM59250.1 - 1e-89 301.2 28.8 1.3e-89 300.8 19.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM59250.1 - 6.3e-37 127.0 50.4 1.2e-31 109.7 16.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 KUM59251.1 - 1.1e-28 99.8 1.3 1.7e-28 99.2 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.1 KUM59252.1 - 1e-26 94.2 0.0 1.4e-26 93.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KUM59252.1 - 1.6e-23 83.4 0.1 2.2e-23 83.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM59252.1 - 1.1e-09 38.2 0.1 2.6e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM59252.1 - 0.0037 16.7 0.1 0.0062 15.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KUM59252.1 - 0.018 14.8 0.4 0.043 13.5 0.3 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 KUM59252.1 - 0.04 12.9 0.1 0.081 12.0 0.1 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NADH-u_ox-rdase PF10785.4 KUM59253.1 - 0.091 13.0 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Glyco_hydro_2_N PF02837.13 KUM59254.1 - 1.8e-10 40.6 0.1 4.7e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KUM59254.1 - 1.9e-06 27.0 0.1 3.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 KUM59254.1 - 1.4e-05 25.5 0.0 6.6e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Cyt-b5 PF00173.23 KUM59255.1 - 2.6e-20 71.9 0.0 3.6e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FMN_dh PF01070.13 KUM59255.1 - 0.033 13.0 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Cyclin_N PF00134.18 KUM59256.1 - 1.1e-05 25.0 0.0 0.0027 17.2 0.0 2.7 2 1 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.14 KUM59256.1 - 0.00098 18.8 0.0 0.044 13.5 0.0 2.4 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Zn_ribbon_recom PF13408.1 KUM59257.1 - 0.26 11.5 3.0 0.76 10.0 0.2 2.3 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain zf-ribbon_3 PF13248.1 KUM59257.1 - 0.31 10.2 1.6 0.51 9.6 0.2 1.9 2 0 0 2 2 2 0 zinc-ribbon domain Polysacc_deac_2 PF04748.8 KUM59258.1 - 0.017 14.1 3.4 0.027 13.4 2.3 1.2 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase DUF2856 PF11043.3 KUM59258.1 - 0.034 14.2 0.4 0.034 14.2 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2856) Spore_coat_CotO PF14153.1 KUM59258.1 - 0.084 12.3 3.8 0.1 12.0 2.6 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Translin PF01997.11 KUM59258.1 - 0.089 12.3 2.7 0.095 12.2 1.3 1.5 1 1 0 1 1 1 0 Translin family DUF812 PF05667.6 KUM59258.1 - 0.092 11.2 8.3 0.13 10.7 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) SPX PF03105.14 KUM59258.1 - 0.12 12.1 2.9 0.17 11.6 2.0 1.5 1 1 0 1 1 1 0 SPX domain DUF3450 PF11932.3 KUM59258.1 - 0.17 11.1 9.5 0.23 10.7 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) IncA PF04156.9 KUM59258.1 - 0.42 10.1 6.9 0.66 9.5 4.8 1.2 1 0 0 1 1 1 0 IncA protein DUF2570 PF10828.3 KUM59258.1 - 0.6 9.7 6.4 0.2 11.2 2.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) Tweety PF04906.8 KUM59258.1 - 0.68 8.2 2.7 0.95 7.7 1.9 1.1 1 0 0 1 1 1 0 Tweety Spc7 PF08317.6 KUM59258.1 - 0.74 8.4 8.6 1.1 7.8 6.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.4 KUM59258.1 - 2.9 6.7 7.8 4 6.2 5.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Orbi_VP5 PF00901.12 KUM59258.1 - 4.7 5.2 9.4 6.4 4.8 6.5 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Latarcin PF10279.4 KUM59258.1 - 7.4 6.8 13.7 39 4.5 9.5 2.1 1 1 0 1 1 1 0 Latarcin precursor Fez1 PF06818.10 KUM59261.1 - 0.039 13.9 0.5 0.066 13.2 0.4 1.3 1 0 0 1 1 1 0 Fez1 Striatin PF08232.7 KUM59261.1 - 0.041 14.1 0.1 0.095 13.0 0.1 1.6 1 0 0 1 1 1 0 Striatin family Autophagy_N PF03986.8 KUM59262.1 - 1.2e-49 167.8 0.0 2.2e-49 166.9 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 KUM59262.1 - 8e-22 77.1 0.1 1.7e-21 76.1 0.1 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 KUM59262.1 - 2.1e-14 52.2 0.5 3.5e-14 51.5 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Glycos_transf_2 PF00535.21 KUM59264.1 - 3.6e-20 72.3 0.0 1.4e-09 37.8 0.0 2.7 1 1 1 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KUM59264.1 - 5.1e-08 33.0 0.6 0.007 16.1 0.0 3.5 1 1 2 4 4 4 2 Glycosyltransferase like family 2 Aldo_ket_red PF00248.16 KUM59265.1 - 1.2e-47 162.1 0.0 1.5e-47 161.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Init_tRNA_PT PF04179.7 KUM59266.1 - 1.1e-133 446.4 0.0 3.2e-100 336.1 0.0 2.0 2 0 0 2 2 2 2 Initiator tRNA phosphoribosyl transferase HAD_2 PF13419.1 KUM59267.1 - 5.5e-16 59.2 0.0 8.1e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KUM59267.1 - 5.4e-08 32.4 0.1 1.3e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KUM59267.1 - 5.1e-05 23.7 0.1 0.00043 20.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.13 KUM59267.1 - 0.0023 17.6 0.0 0.037 13.7 0.0 2.2 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Sar8_2 PF03058.9 KUM59267.1 - 0.047 14.0 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 Sar8.2 family NUDIX PF00293.23 KUM59268.1 - 5.9e-19 68.0 0.0 9e-19 67.4 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.23 KUM59269.1 - 0.00013 21.6 0.0 0.00038 20.1 0.0 1.9 1 1 0 1 1 1 1 NUDIX domain EST1_DNA_bind PF10373.4 KUM59270.1 - 1.4e-08 34.3 0.0 3.1e-08 33.1 0.0 1.7 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain Creatinase_N PF01321.13 KUM59272.1 - 0.00063 20.2 0.0 0.0007 20.0 0.0 1.1 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain SOR_SNZ PF01680.12 KUM59273.1 - 1.7e-109 364.2 6.6 1.7e-109 364.2 4.6 1.6 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.9 KUM59273.1 - 7.3e-09 35.0 7.3 2.4e-06 26.8 0.2 2.5 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 KUM59273.1 - 0.00027 19.8 0.4 0.18 10.6 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 KUM59273.1 - 0.00071 18.9 0.6 0.12 11.6 0.0 3.2 2 2 1 3 3 3 1 Histidine biosynthesis protein IGPS PF00218.16 KUM59273.1 - 0.0016 17.5 0.1 0.043 12.8 0.0 2.5 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.9 KUM59273.1 - 0.0064 15.4 1.0 0.14 11.1 0.0 2.5 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.10 KUM59273.1 - 0.018 14.1 0.5 0.018 14.1 0.3 2.4 2 1 0 2 2 2 0 Nitronate monooxygenase PEP_mutase PF13714.1 KUM59273.1 - 0.027 13.7 3.3 0.3 10.2 0.2 2.9 2 1 1 3 3 3 0 Phosphoenolpyruvate phosphomutase IBN_N PF03810.14 KUM59274.1 - 2.6e-05 24.0 1.1 7.8e-05 22.5 0.8 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain Phage_Coat_Gp8 PF05371.7 KUM59274.1 - 0.092 12.3 2.4 0.81 9.2 0.1 2.8 2 0 0 2 2 2 0 Phage major coat protein, Gp8 DUF577 PF04510.7 KUM59274.1 - 0.12 12.0 0.2 0.34 10.5 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF577) ORC2 PF04084.9 KUM59275.1 - 2.2e-96 322.5 0.0 2.9e-96 322.1 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 NTP_transf_3 PF12804.2 KUM59275.1 - 0.095 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain ORC6 PF05460.8 KUM59275.1 - 0.2 10.7 9.9 0.35 9.9 6.9 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) FUN14 PF04930.10 KUM59276.1 - 8.7e-11 41.9 1.0 1.7e-10 41.0 0.7 1.5 1 1 0 1 1 1 1 FUN14 family DUF543 PF04418.7 KUM59276.1 - 0.00073 19.4 1.1 0.2 11.6 0.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF543) SecY PF00344.15 KUM59277.1 - 1.2e-96 323.7 9.3 1.5e-96 323.4 6.5 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 KUM59277.1 - 4.8e-18 64.3 0.3 1.5e-17 62.7 0.2 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p ArgJ PF01960.13 KUM59278.1 - 2.2e-145 483.9 0.4 2.6e-145 483.7 0.3 1.0 1 0 0 1 1 1 1 ArgJ family Abhydrolase_1 PF00561.15 KUM59279.1 - 1.8e-22 80.0 0.0 6.1e-22 78.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 KUM59279.1 - 1.1e-18 66.9 0.0 2.5e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 KUM59279.1 - 1.1e-12 48.3 0.4 2.3e-12 47.3 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM59279.1 - 8.9e-06 25.5 0.0 5.4e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family ABC2_membrane PF01061.19 KUM59280.1 - 4.2e-41 140.4 17.4 7.5e-41 139.6 12.1 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KUM59280.1 - 1.1e-18 67.8 0.0 2.1e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 KUM59280.1 - 4.1e-07 29.3 5.3 4.1e-07 29.3 3.7 1.6 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_22 PF13401.1 KUM59280.1 - 0.00013 22.0 0.0 0.00039 20.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KUM59280.1 - 0.00032 20.1 0.1 0.00085 18.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KUM59280.1 - 0.0046 16.1 0.0 0.0085 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KUM59280.1 - 0.0087 16.0 0.2 0.016 15.1 0.2 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 KUM59280.1 - 0.013 15.0 0.6 0.03 13.8 0.2 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain PDR_CDR PF06422.7 KUM59280.1 - 0.022 14.3 0.0 0.05 13.2 0.0 1.6 1 0 0 1 1 1 0 CDR ABC transporter AAA_21 PF13304.1 KUM59280.1 - 0.033 14.1 2.9 0.58 10.0 0.0 3.3 3 1 0 3 3 3 0 AAA domain AAA_28 PF13521.1 KUM59280.1 - 0.051 13.5 0.3 0.1 12.5 0.2 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KUM59280.1 - 0.072 12.5 0.3 0.14 11.6 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 KUM59280.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Dynamin family AAA_18 PF13238.1 KUM59280.1 - 0.16 12.2 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 KUM59280.1 - 0.22 10.7 0.0 2.5 7.2 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ApbA PF02558.11 KUM59281.1 - 0.035 13.5 0.0 0.065 12.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF1754 PF08555.5 KUM59282.1 - 5.6e-13 49.3 16.1 9.6e-13 48.5 11.1 1.4 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) MTTB PF06253.6 KUM59282.1 - 0.026 12.3 0.8 0.031 12.0 0.6 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) Geminin PF07412.7 KUM59282.1 - 0.35 10.5 10.6 0.46 10.1 7.3 1.1 1 0 0 1 1 1 0 Geminin Spt5_N PF11942.3 KUM59282.1 - 0.53 10.9 11.9 0.077 13.6 4.8 1.8 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal CAF-1_p150 PF11600.3 KUM59282.1 - 2 7.7 22.1 2.4 7.4 15.3 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Vfa1 PF08432.5 KUM59282.1 - 2.5 8.1 10.9 3.2 7.7 7.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2201_N PF13203.1 KUM59282.1 - 5.9 5.9 8.3 7 5.7 5.8 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain zf-AN1 PF01428.11 KUM59283.1 - 2.3e-11 43.3 12.7 3.2e-11 42.9 8.8 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger DUF4187 PF13821.1 KUM59283.1 - 0.12 11.9 2.2 0.18 11.4 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) Tubulin PF00091.20 KUM59284.1 - 7.1e-75 251.5 0.0 1.2e-74 250.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KUM59284.1 - 5.8e-44 149.1 0.4 9.2e-44 148.5 0.0 1.5 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KUM59284.1 - 1.3e-08 34.8 0.0 3.2e-08 33.6 0.0 1.6 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Asp_Glu_race PF01177.17 KUM59285.1 - 4.5e-19 69.2 0.0 5.5e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Aldo_ket_red PF00248.16 KUM59286.1 - 4.5e-51 173.3 0.0 6.3e-51 172.8 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family EamA PF00892.15 KUM59286.1 - 5.3e-11 42.6 22.4 1.6e-05 24.9 10.2 2.5 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 KUM59286.1 - 3.9e-06 27.0 17.3 8.3e-05 22.7 0.1 2.7 2 0 0 2 2 2 2 Multidrug resistance efflux transporter DUF914 PF06027.7 KUM59286.1 - 0.0065 15.3 0.7 0.013 14.3 0.5 1.5 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) Nuc_sug_transp PF04142.10 KUM59286.1 - 0.018 14.1 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 Nucleotide-sugar transporter TPT PF03151.11 KUM59286.1 - 0.039 13.5 13.9 0.057 13.0 5.8 2.6 2 0 0 2 2 2 0 Triose-phosphate Transporter family DUF202 PF02656.10 KUM59286.1 - 0.05 13.8 6.8 0.093 12.9 0.3 3.9 4 1 0 4 4 4 0 Domain of unknown function (DUF202) ABC2_membrane PF01061.19 KUM59288.1 - 1.6e-23 82.9 6.3 2.2e-23 82.5 4.4 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KUM59288.1 - 1.4e-16 61.0 0.0 2.8e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_trans_N PF14510.1 KUM59288.1 - 2.2e-08 34.0 0.0 5.4e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane PF01061.19 KUM59289.1 - 9.8e-16 57.5 4.7 1.3e-15 57.1 3.3 1.2 1 0 0 1 1 1 1 ABC-2 type transporter PDR_CDR PF06422.7 KUM59289.1 - 1.5e-10 40.6 0.0 1.5e-10 40.6 0.0 2.0 3 0 0 3 3 3 1 CDR ABC transporter ABC2_membrane_3 PF12698.2 KUM59289.1 - 4.1e-05 22.7 1.0 4.1e-05 22.7 0.7 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein DSPc PF00782.15 KUM59290.1 - 1.4e-13 50.5 0.4 2.6e-13 49.7 0.3 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 KUM59290.1 - 0.0054 15.6 0.1 0.0074 15.2 0.0 1.2 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase PF00102.22 KUM59290.1 - 0.12 11.6 0.1 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase ArabFuran-catal PF09206.6 KUM59292.1 - 5.3e-161 534.9 19.0 8.7e-161 534.2 13.2 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.8 KUM59292.1 - 7.1e-61 204.0 2.9 1.2e-60 203.3 2.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) CBM_20 PF00686.14 KUM59293.1 - 2.5e-35 119.9 0.3 5.9e-35 118.7 0.2 1.7 1 0 0 1 1 1 1 Starch binding domain Chitin_bind_3 PF03067.10 KUM59293.1 - 2e-07 31.4 0.7 0.00015 22.1 0.0 2.5 2 0 0 2 2 2 2 Chitin binding domain Sporozoite_P67 PF05642.6 KUM59293.1 - 0.011 13.6 1.4 0.013 13.4 1.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PTPA PF03095.10 KUM59294.1 - 5.9e-111 370.4 0.0 6.9e-111 370.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF2946 PF11162.3 KUM59294.1 - 0.11 12.7 0.9 0.26 11.5 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) DUF202 PF02656.10 KUM59295.1 - 1.1e-26 92.8 0.7 1.1e-26 92.8 0.5 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Cytochrom_B_N PF00033.14 KUM59295.1 - 0.036 13.4 1.5 0.054 12.8 1.0 1.2 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Lin-8 PF03353.10 KUM59295.1 - 0.58 9.3 3.4 0.75 9.0 2.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SOG2 PF10428.4 KUM59295.1 - 0.84 8.2 11.4 1.1 7.8 7.9 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein PIH1 PF08190.7 KUM59295.1 - 1.3 8.3 5.3 1.8 7.9 3.7 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Macoilin PF09726.4 KUM59295.1 - 4.9 5.3 10.7 6.2 4.9 7.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Actin PF00022.14 KUM59297.1 - 1.3e-115 386.0 0.0 1.6e-115 385.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KUM59297.1 - 0.0076 14.8 0.0 0.039 12.5 0.0 1.9 1 1 0 1 1 1 1 MreB/Mbl protein NAD_binding_2 PF03446.10 KUM59298.1 - 9.5e-29 100.3 0.1 1.5e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KUM59298.1 - 4.9e-13 49.2 0.0 1.6e-12 47.5 0.0 1.8 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KUM59298.1 - 8.9e-05 22.8 0.0 0.00067 20.0 0.0 2.4 1 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent IMPDH PF00478.20 KUM59298.1 - 0.045 12.6 0.7 0.67 8.7 0.2 2.3 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Oxidored-like PF09791.4 KUM59300.1 - 4.4e-05 22.8 6.2 8.9e-05 21.8 4.3 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Red1 PF07964.6 KUM59300.1 - 0.14 10.3 4.3 0.19 9.8 3.0 1.2 1 0 0 1 1 1 0 Rec10 / Red1 Mid1 PF12929.2 KUM59301.1 - 1e-150 502.2 7.0 1.4e-150 501.8 4.9 1.2 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 KUM59301.1 - 0.033 14.5 2.1 1.7 9.0 0.2 2.7 2 0 0 2 2 2 0 Fz domain Brix PF04427.13 KUM59303.1 - 5.3e-40 137.1 0.2 7.6e-40 136.6 0.1 1.2 1 0 0 1 1 1 1 Brix domain Nop14 PF04147.7 KUM59303.1 - 1.3 6.8 27.3 1.8 6.4 18.9 1.1 1 0 0 1 1 1 0 Nop14-like family tRNA-synt_2b PF00587.20 KUM59304.1 - 3.3e-66 222.1 0.1 5.2e-66 221.4 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KUM59304.1 - 4.1e-21 74.7 0.0 4.1e-21 74.7 0.0 2.8 3 1 1 4 4 4 1 Anticodon binding domain Acyltransferase PF01553.16 KUM59305.1 - 6.4e-26 90.3 0.0 9.4e-26 89.8 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase NAD_kinase PF01513.16 KUM59306.1 - 8e-50 169.2 0.0 1.1e-49 168.7 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase PBD PF00786.23 KUM59307.1 - 0.053 13.9 1.6 0.14 12.6 0.1 2.6 2 0 0 2 2 2 0 P21-Rho-binding domain TPR_2 PF07719.12 KUM59308.1 - 1e-26 90.6 21.0 0.0002 21.0 0.2 11.2 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_11 PF13414.1 KUM59308.1 - 5.9e-26 89.9 27.8 7.1e-06 25.5 0.0 10.1 10 1 3 13 13 13 7 TPR repeat TPR_1 PF00515.23 KUM59308.1 - 2.6e-21 74.2 15.0 0.0018 17.7 0.0 9.9 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.1 KUM59308.1 - 1.8e-18 66.6 24.3 1.3e-06 28.6 0.2 8.9 10 1 1 11 11 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 KUM59308.1 - 6.2e-16 57.4 27.6 0.0072 16.8 0.0 10.9 10 3 2 12 12 10 5 Tetratricopeptide repeat TPR_8 PF13181.1 KUM59308.1 - 7.6e-15 53.5 15.0 0.0098 15.6 0.0 9.4 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 KUM59308.1 - 5.5e-12 46.0 35.1 0.00012 22.6 0.0 11.0 10 1 1 11 11 10 4 Tetratricopeptide repeat TPR_12 PF13424.1 KUM59308.1 - 2.6e-10 40.0 31.7 0.00092 19.1 0.3 9.2 7 3 4 11 11 10 5 Tetratricopeptide repeat TPR_7 PF13176.1 KUM59308.1 - 3.1e-07 29.6 20.4 0.0046 16.6 0.1 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 KUM59308.1 - 1.3e-06 28.0 12.2 0.82 10.0 0.0 10.4 11 1 1 12 12 11 1 Tetratricopeptide repeat TPR_6 PF13174.1 KUM59308.1 - 3.6e-05 23.9 28.4 0.013 15.8 0.1 10.7 13 0 0 13 13 12 2 Tetratricopeptide repeat TPR_4 PF07721.9 KUM59308.1 - 0.013 15.8 3.2 3.7 8.2 0.8 4.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Es2 PF09751.4 KUM59309.1 - 1.7e-113 380.1 1.9 2e-113 379.9 1.3 1.0 1 0 0 1 1 1 1 Nuclear protein Es2 APOC4 PF15119.1 KUM59309.1 - 0.044 13.7 0.1 1.9 8.5 0.0 2.5 2 0 0 2 2 2 0 Apolipoprotein C4 Herpes_LMP1 PF05297.6 KUM59309.1 - 0.22 10.3 0.5 0.32 9.8 0.4 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Binary_toxB PF03495.9 KUM59310.1 - 2.2 6.8 4.2 2.4 6.6 2.9 1.1 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA adh_short PF00106.20 KUM59311.1 - 2.8e-23 82.6 0.0 3.9e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM59311.1 - 7e-09 35.8 0.0 9e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM59311.1 - 5.1e-07 29.5 0.0 2.7e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KUM59311.1 - 0.015 15.0 0.2 0.029 14.1 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase CP_ATPgrasp_2 PF14403.1 KUM59312.1 - 0.0013 17.5 0.0 0.28 9.7 0.0 2.1 2 0 0 2 2 2 2 Circularly permuted ATP-grasp type 2 Sigma70_r1_1 PF03979.9 KUM59312.1 - 0.025 14.5 0.1 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 Bacteriocin_IIi PF11758.3 KUM59313.1 - 0.0077 15.8 0.5 1.1 8.8 0.6 3.3 3 0 0 3 3 3 1 Aureocin-like type II bacteriocin CP_ATPgrasp_2 PF14403.1 KUM59314.1 - 0.0027 16.4 0.0 0.004 15.8 0.0 1.2 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 TTL PF03133.10 KUM59314.1 - 0.003 16.5 0.0 0.004 16.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.1 KUM59314.1 - 0.012 14.7 0.0 0.019 14.0 0.0 1.3 1 1 0 1 1 1 0 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.1 KUM59314.1 - 0.12 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain DUF3625 PF12293.3 KUM59315.1 - 0.063 12.3 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3625) Pkinase PF00069.20 KUM59316.1 - 4.3e-69 232.5 0.0 8e-69 231.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM59316.1 - 1.4e-50 171.8 0.0 1.4e-50 171.8 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 KUM59316.1 - 1.3e-23 83.2 0.5 9e-23 80.4 0.0 2.7 2 0 0 2 2 2 1 P21-Rho-binding domain PH_11 PF15413.1 KUM59316.1 - 1.9e-17 63.5 0.1 4.2e-17 62.4 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.1 KUM59316.1 - 6.1e-07 28.6 0.0 1.3e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Kinase-like PH PF00169.24 KUM59316.1 - 1.4e-05 25.2 0.1 2.7e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 PH domain APH PF01636.18 KUM59316.1 - 0.016 14.9 1.5 0.018 14.7 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KUM59316.1 - 0.039 12.7 0.1 0.066 12.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DNA_pol_E_B PF04042.11 KUM59317.1 - 6.6e-48 162.7 0.0 9.4e-48 162.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Med14 PF08638.6 KUM59318.1 - 5.3e-74 247.7 0.0 8.3e-74 247.0 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 ATG22 PF11700.3 KUM59320.1 - 2e-214 712.4 17.0 2.3e-214 712.2 11.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KUM59320.1 - 6.5e-08 31.6 19.3 6.5e-08 31.6 13.4 3.2 2 1 0 3 3 3 2 Major Facilitator Superfamily ODC_AZ PF02100.12 KUM59321.1 - 1.1e-28 98.9 0.0 1.2e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Yippee-Mis18 PF03226.9 KUM59323.1 - 3.1e-23 81.6 0.1 5.3e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly ProSAAS PF07259.7 KUM59323.1 - 0.083 12.4 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 ProSAAS precursor SHNi-TPR PF10516.4 KUM59324.1 - 4.8e-14 51.3 1.7 6.5e-14 50.8 0.2 2.1 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.1 KUM59324.1 - 6.2e-08 32.4 3.8 0.0052 16.7 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KUM59324.1 - 1.7e-07 30.7 1.7 0.017 14.7 0.0 2.7 2 1 0 2 2 2 2 TPR repeat TPR_16 PF13432.1 KUM59324.1 - 0.0095 16.5 4.0 1.2 9.9 1.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KUM59324.1 - 0.021 14.6 4.1 1.3 8.9 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat CCDC-167 PF15188.1 KUM59324.1 - 0.15 12.0 7.9 0.033 14.1 2.3 2.3 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Snapin_Pallidin PF14712.1 KUM59324.1 - 0.44 10.8 4.6 2.1 8.6 0.6 3.1 3 0 0 3 3 3 0 Snapin/Pallidin TPR_2 PF07719.12 KUM59324.1 - 5 7.2 0.0 5 7.2 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Thioredoxin PF00085.15 KUM59325.1 - 4.5e-64 212.6 4.5 2e-32 110.9 0.1 4.2 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 KUM59325.1 - 1e-51 175.4 5.6 1.4e-38 132.5 0.4 3.7 3 1 1 4 4 4 3 Thioredoxin-like domain Redoxin PF08534.5 KUM59325.1 - 8.5e-11 41.6 5.1 0.0017 17.8 0.1 3.5 3 0 0 3 3 3 3 Redoxin Thioredoxin_8 PF13905.1 KUM59325.1 - 1e-10 41.6 0.2 0.00072 19.6 0.0 3.7 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.1 KUM59325.1 - 1.5e-10 40.8 0.2 0.0026 17.7 0.0 3.7 3 0 0 3 3 3 2 Thioredoxin-like Calsequestrin PF01216.12 KUM59325.1 - 1.6e-10 40.3 2.3 1.7e-10 40.2 0.4 1.8 3 0 0 3 3 3 1 Calsequestrin Thioredoxin_2 PF13098.1 KUM59325.1 - 1.7e-10 41.0 4.0 0.0013 18.8 0.1 4.1 2 2 1 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.16 KUM59325.1 - 2.5e-09 36.8 2.6 0.00011 21.8 0.0 3.6 3 0 0 3 3 3 2 AhpC/TSA family ERp29_N PF07912.8 KUM59325.1 - 1.7e-05 24.7 0.2 0.24 11.3 0.0 4.0 4 0 0 4 4 4 2 ERp29, N-terminal domain DUF4259 PF14078.1 KUM59325.1 - 0.02 15.4 0.9 2.9 8.4 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) Thioredoxin_3 PF13192.1 KUM59325.1 - 0.061 13.1 0.6 0.29 10.9 0.1 2.4 2 0 0 2 2 2 0 Thioredoxin domain Mu-like_Com PF10122.4 KUM59325.1 - 0.31 10.1 1.0 23 4.1 0.0 2.4 2 0 0 2 2 2 0 Mu-like prophage protein Com Thioredoxin_4 PF13462.1 KUM59325.1 - 0.67 9.9 7.8 5.4 6.9 0.0 3.7 4 0 0 4 4 4 0 Thioredoxin UDG PF03167.14 KUM59326.1 - 6.2e-26 90.6 0.1 9.4e-26 90.1 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily MFS_1 PF07690.11 KUM59327.1 - 8.5e-32 110.2 20.0 8.5e-32 110.2 13.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM59327.1 - 3.7e-10 38.9 3.5 3.7e-10 38.9 2.4 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 KUM59327.1 - 0.0011 17.4 3.0 0.0011 17.4 2.0 3.0 2 1 1 3 3 3 1 MFS/sugar transport protein MFS_3 PF05977.8 KUM59327.1 - 0.014 13.5 5.1 0.11 10.5 1.8 2.4 1 1 1 2 2 2 0 Transmembrane secretion effector DWNN PF08783.6 KUM59328.1 - 3.9e-32 110.0 0.1 3.9e-32 110.0 0.1 1.8 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.1 KUM59328.1 - 6.5e-06 25.5 7.3 1.8e-05 24.1 5.1 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KUM59328.1 - 0.0083 16.0 1.2 0.019 14.8 0.8 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-Nse PF11789.3 KUM59328.1 - 0.37 10.3 3.7 0.81 9.2 2.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.20 KUM59328.1 - 2.9 7.6 8.2 6.5 6.5 5.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KUM59328.1 - 5.3 6.9 9.6 13 5.7 6.7 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KUM59328.1 - 5.8 6.7 11.4 0.31 10.7 3.7 2.0 2 0 0 2 2 2 0 zinc-RING finger domain His_biosynth PF00977.16 KUM59329.1 - 2.8e-45 154.3 0.4 7.3e-45 153.0 0.3 1.7 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 KUM59329.1 - 9.7e-30 103.4 0.0 1.6e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 KUM59329.1 - 1.5e-10 41.0 0.0 1.3e-08 34.7 0.0 2.2 2 0 0 2 2 2 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 KUM59329.1 - 5.2e-10 39.1 0.0 1.1e-09 38.0 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 KUM59329.1 - 0.0003 20.2 0.0 0.00065 19.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 UPF0180 PF03698.8 KUM59329.1 - 0.053 13.3 0.2 3.9 7.3 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0180) Dus PF01207.12 KUM59329.1 - 0.14 10.9 0.0 0.28 9.9 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) dCMP_cyt_deam_1 PF00383.17 KUM59330.1 - 5.7e-27 93.3 1.0 8.2e-27 92.8 0.7 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region PSD5 PF07637.6 KUM59330.1 - 0.072 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1595) ThiF PF00899.16 KUM59331.1 - 7.7e-28 97.0 0.0 1.3e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 KUM59331.1 - 0.00052 20.1 0.0 0.008 16.2 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FtsJ PF01728.14 KUM59332.1 - 8.3e-60 201.8 0.0 1e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 KUM59332.1 - 9.4e-06 25.4 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM59332.1 - 0.00025 21.6 0.0 0.00069 20.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM59332.1 - 0.002 17.7 0.0 0.55 9.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 KUM59332.1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KUM59332.1 - 0.093 13.2 0.0 12 6.4 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain Peptidase_S49_N PF08496.5 KUM59333.1 - 0.18 11.6 9.3 0.39 10.4 3.9 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Fungal_trans PF04082.13 KUM59334.1 - 1.6e-36 125.5 1.4 2.6e-36 124.8 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM59334.1 - 0.00077 19.3 17.6 0.0014 18.5 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KUM59335.1 - 8.9e-13 47.6 0.0 1.7e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAM163 PF15069.1 KUM59335.1 - 0.33 11.5 2.0 5.9 7.4 0.1 2.7 2 0 0 2 2 2 0 FAM163 family Kinetocho_Slk19 PF12709.2 KUM59336.1 - 6.3e-23 80.6 22.5 3.6e-22 78.2 4.2 4.4 4 1 1 5 5 5 2 Central kinetochore-associated Fib_alpha PF08702.5 KUM59336.1 - 0.2 11.7 4.7 17 5.5 2.3 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF208 PF02677.9 KUM59336.1 - 3.2 7.5 5.5 5.7 6.6 3.8 1.3 1 0 0 1 1 1 0 Uncharacterized BCR, COG1636 DUF4407 PF14362.1 KUM59336.1 - 5 6.0 29.4 8.7 5.2 10.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Filament PF00038.16 KUM59336.1 - 6.2 6.1 33.7 74 2.6 23.4 2.8 1 1 0 1 1 1 0 Intermediate filament protein DUF1664 PF07889.7 KUM59336.1 - 10 5.9 13.2 0.22 11.3 2.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Dyp_perox PF04261.7 KUM59337.1 - 2.7e-10 39.4 0.0 9.1e-09 34.4 0.0 2.9 2 1 0 2 2 2 1 Dyp-type peroxidase family DUF2347 PF09804.4 KUM59338.1 - 5.2e-104 347.4 0.0 7.5e-104 346.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 KUM59338.1 - 1.3e-58 197.9 0.4 1.9e-58 197.4 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) Avl9 PF09794.4 KUM59338.1 - 0.0012 17.4 0.0 1.2 7.4 0.0 2.5 2 1 0 3 3 3 2 Transport protein Avl9 SPA PF08616.5 KUM59338.1 - 0.0047 16.6 0.0 0.011 15.4 0.0 1.6 1 1 0 1 1 1 1 Stabilization of polarity axis Tubulin_3 PF14881.1 KUM59340.1 - 6.9e-60 201.6 0.0 1.1e-59 200.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.20 KUM59340.1 - 0.13 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain adh_short PF00106.20 KUM59342.1 - 1.4e-25 90.1 7.1 2.2e-25 89.5 4.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM59342.1 - 7.8e-24 84.7 1.8 9e-24 84.5 1.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM59342.1 - 3.3e-13 49.6 3.6 4.8e-13 49.1 2.5 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM59342.1 - 0.00019 20.9 1.5 0.00051 19.5 1.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AA_permease PF00324.16 KUM59343.1 - 8.1e-47 159.6 8.6 8.9e-47 159.4 5.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KUM59343.1 - 2.4e-11 42.8 10.8 3.1e-11 42.4 7.5 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1929 PF09118.6 KUM59344.1 - 4.3e-23 81.2 0.0 8.5e-23 80.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) F5_F8_type_C PF00754.20 KUM59344.1 - 5.7e-19 68.2 0.2 1.5e-18 66.8 0.2 1.8 1 0 0 1 1 1 1 F5/8 type C domain Kelch_6 PF13964.1 KUM59344.1 - 3.9e-15 55.2 1.9 9.3e-07 28.7 0.0 4.6 5 1 1 6 6 6 2 Kelch motif Kelch_4 PF13418.1 KUM59344.1 - 1.1e-13 50.7 6.2 0.00052 19.7 0.0 5.1 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.20 KUM59344.1 - 2.6e-13 49.3 0.2 2.5e-05 23.7 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Glyoxal_oxid_N PF07250.6 KUM59344.1 - 2.4e-10 39.9 0.3 0.00014 21.0 0.1 2.8 2 1 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_3 PF13415.1 KUM59344.1 - 2.8e-07 30.4 0.4 0.16 12.2 0.0 4.8 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 KUM59344.1 - 4.4e-07 29.4 0.5 0.11 12.3 0.0 4.6 4 1 0 4 4 4 2 Kelch motif SWIM PF04434.12 KUM59344.1 - 0.081 12.4 0.2 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 SWIM zinc finger p450 PF00067.17 KUM59345.1 - 5.4e-39 133.9 0.0 7e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ank_2 PF12796.2 KUM59347.1 - 4.5e-12 46.1 2.9 0.017 15.4 0.3 6.6 4 1 1 5 5 5 3 Ankyrin repeats (3 copies) NACHT PF05729.7 KUM59347.1 - 3.6e-09 36.5 0.0 8.5e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KUM59347.1 - 0.00027 21.0 0.0 0.0013 18.8 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KUM59347.1 - 0.00053 20.0 2.1 0.00089 19.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 KUM59347.1 - 0.092 12.9 0.1 0.81 9.8 0.1 2.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KUM59347.1 - 0.16 12.1 0.0 0.44 10.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Ank PF00023.25 KUM59347.1 - 0.21 11.4 5.8 56 3.8 0.0 5.8 6 0 0 6 6 6 0 Ankyrin repeat adh_short PF00106.20 KUM59348.1 - 1.1e-32 113.2 0.7 1.3e-32 112.9 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM59348.1 - 2.9e-32 112.3 0.2 3.4e-32 112.1 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM59348.1 - 4.7e-13 49.2 0.3 7.3e-13 48.5 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM59348.1 - 2e-05 24.1 0.2 3.3e-05 23.4 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 KUM59348.1 - 0.0016 18.0 1.9 0.0026 17.4 1.3 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 KUM59348.1 - 0.034 13.9 0.4 0.26 11.1 0.2 2.4 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain THF_DHG_CYH_C PF02882.14 KUM59348.1 - 0.036 13.1 0.3 0.071 12.1 0.1 1.5 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_2 PF03446.10 KUM59348.1 - 0.046 13.5 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KUM59348.1 - 0.05 14.0 0.5 0.089 13.2 0.3 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 KUM59348.1 - 0.092 11.4 0.1 0.13 10.9 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family CheY-binding PF09078.6 KUM59348.1 - 0.11 12.5 0.1 0.49 10.4 0.1 2.0 2 0 0 2 2 2 0 CheY binding RNA_pol_Rpb1_4 PF05000.12 KUM59348.1 - 0.12 12.0 1.0 0.22 11.2 0.7 1.5 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 4 Cys_rich_VLP PF14194.1 KUM59348.1 - 0.16 11.7 0.4 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Cysteine-rich VLP Sugar_tr PF00083.19 KUM59349.1 - 1.9e-70 237.6 34.1 2.3e-70 237.4 23.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM59349.1 - 8.2e-30 103.7 31.3 8.2e-30 103.7 21.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltrans_Mon PF14314.1 KUM59350.1 - 0.047 11.5 0.1 0.066 11.0 0.0 1.1 1 0 0 1 1 1 0 Virus-capping methyltransferase TA0956 PF11513.3 KUM59350.1 - 0.14 12.2 0.0 0.5 10.4 0.0 1.9 2 0 0 2 2 2 0 Thermoplasma acidophilum protein TA0956 adh_short PF00106.20 KUM59351.1 - 3.2e-28 98.7 0.1 4.9e-28 98.1 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM59351.1 - 7.6e-22 78.2 0.4 2.6e-20 73.2 0.1 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM59351.1 - 9.4e-18 64.5 0.0 1.3e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM59351.1 - 2.8e-08 33.4 0.2 4.8e-08 32.7 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KUM59351.1 - 0.00036 19.5 0.1 0.00056 18.8 0.1 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein ANKH PF07260.6 KUM59351.1 - 0.017 14.1 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Progressive ankylosis protein (ANKH) RmlD_sub_bind PF04321.12 KUM59351.1 - 0.034 13.0 0.1 0.069 12.0 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Dak1_2 PF13684.1 KUM59351.1 - 0.042 12.8 0.0 0.066 12.1 0.0 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family 3Beta_HSD PF01073.14 KUM59351.1 - 0.08 11.6 0.0 0.49 9.0 0.0 2.0 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family HSP70 PF00012.15 KUM59354.1 - 1.4e-65 221.4 5.8 1.4e-65 221.4 4.0 2.6 2 1 0 2 2 2 1 Hsp70 protein XPA_C PF05181.7 KUM59356.1 - 1.4e-23 82.1 5.6 2.2e-14 52.7 0.1 2.6 2 0 0 2 2 2 2 XPA protein C-terminus DUF87 PF01935.12 KUM59356.1 - 0.39 10.5 1.5 0.42 10.3 0.1 1.7 2 1 0 2 2 2 0 Domain of unknown function DUF87 XPA_N PF01286.13 KUM59356.1 - 1.5 8.5 13.8 0.094 12.4 5.5 1.9 2 0 0 2 2 2 0 XPA protein N-terminal ArfGap PF01412.13 KUM59356.1 - 3.6 7.3 11.1 0.12 12.1 2.2 2.5 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf YhfH PF14149.1 KUM59356.1 - 7 6.5 14.3 0.46 10.3 0.7 2.6 2 0 0 2 2 2 0 YhfH-like protein PIG-P PF08510.7 KUM59357.1 - 2.7e-38 130.4 5.8 2.4e-35 120.9 0.1 2.9 3 0 0 3 3 3 2 PIG-P adh_short PF00106.20 KUM59358.1 - 1.3e-29 103.3 0.7 1.9e-29 102.7 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM59358.1 - 2.8e-24 86.2 0.4 3.4e-24 85.9 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM59358.1 - 5.9e-12 45.6 0.2 1e-11 44.8 0.2 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KUM59358.1 - 0.0001 21.9 0.7 0.00026 20.7 0.5 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FNIP_C PF14638.1 KUM59358.1 - 0.0034 16.7 0.2 0.0055 16.0 0.1 1.3 1 0 0 1 1 1 1 Folliculin-interacting protein C-terminus Epimerase PF01370.16 KUM59358.1 - 0.034 13.5 0.1 0.078 12.4 0.1 1.5 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.16 KUM59358.1 - 0.034 14.0 3.0 0.084 12.7 2.1 1.7 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain HAD_2 PF13419.1 KUM59359.1 - 9e-27 94.4 0.0 1.1e-26 94.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KUM59359.1 - 5.9e-05 23.5 0.0 7.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KUM59359.1 - 0.00024 20.7 0.0 0.00042 19.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like ADH_zinc_N PF00107.21 KUM59359.1 - 0.053 13.0 0.2 0.49 9.9 0.1 2.0 2 0 0 2 2 2 0 Zinc-binding dehydrogenase HAD_2 PF13419.1 KUM59360.1 - 1.5e-20 74.1 0.0 3.1e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Prenyltrans_2 PF13249.1 KUM59360.1 - 0.0016 18.8 0.0 3.9 7.9 0.0 3.1 2 1 1 3 3 3 2 Prenyltransferase-like DUF503 PF04456.7 KUM59360.1 - 0.086 12.4 0.0 4.6 6.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF503) RhoGEF PF00621.15 KUM59360.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 RhoGEF domain p450 PF00067.17 KUM59361.1 - 1.4e-71 241.4 0.0 1.8e-71 241.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 KUM59362.1 - 6.8e-83 278.3 0.0 9.1e-83 277.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KUM59362.1 - 4.2e-21 75.0 0.3 7.3e-20 71.0 0.2 2.4 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.20 KUM59362.1 - 6.4e-08 32.7 0.0 3.3e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KUM59362.1 - 0.00026 21.8 0.0 0.00088 20.1 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain p450 PF00067.17 KUM59363.1 - 7.2e-68 229.1 0.0 8.9e-68 228.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 4HBT PF03061.17 KUM59364.1 - 1.6e-12 47.3 1.1 2.9e-12 46.5 0.8 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 KUM59364.1 - 0.073 13.0 0.0 0.089 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) adh_short_C2 PF13561.1 KUM59365.1 - 1.7e-34 119.6 0.4 2.1e-34 119.3 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KUM59365.1 - 6.5e-24 84.7 1.0 8.5e-24 84.3 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM59365.1 - 1.9e-06 27.6 0.5 2.9e-06 27.0 0.4 1.2 1 0 0 1 1 1 1 KR domain HAD_2 PF13419.1 KUM59366.1 - 4e-25 89.0 0.0 4.7e-25 88.8 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KUM59366.1 - 2.2e-06 27.2 0.0 3.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KUM59366.1 - 0.0097 16.3 0.0 0.025 14.9 0.0 1.7 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 KUM59366.1 - 0.093 12.3 0.0 0.16 11.6 0.0 1.6 1 1 0 1 1 1 0 Acid Phosphatase p450 PF00067.17 KUM59367.1 - 2.1e-70 237.5 0.0 2.6e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DS PF01916.12 KUM59368.1 - 4.3e-138 459.4 0.0 5e-138 459.2 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 KUM59368.1 - 0.022 13.9 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase Thioredoxin_9 PF14595.1 KUM59368.1 - 0.057 12.9 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Striatin PF08232.7 KUM59370.1 - 1.5e-41 141.9 5.8 1.5e-41 141.9 4.0 2.1 2 0 0 2 2 2 1 Striatin family WD40 PF00400.27 KUM59370.1 - 6.3e-31 105.1 15.5 8.9e-06 25.4 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KUM59370.1 - 0.065 12.9 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Blt1 PF12754.2 KUM59371.1 - 7.3e-67 226.1 0.1 2e-66 224.6 0.1 1.6 1 1 0 1 1 1 1 Cell-cycle control medial ring component Nol1_Nop2_Fmu PF01189.12 KUM59372.1 - 1.6e-93 313.2 0.2 3.4e-93 312.0 0.0 1.6 2 0 0 2 2 2 1 NOL1/NOP2/sun family FtsJ PF01728.14 KUM59372.1 - 0.0023 17.9 0.0 0.0047 16.9 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 KUM59372.1 - 0.029 13.9 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 KUM59372.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MORN PF02493.15 KUM59373.1 - 9e-15 53.4 22.2 3.2e-05 23.4 0.5 4.7 4 0 0 4 4 4 4 MORN repeat zf-C3HC4_3 PF13920.1 KUM59373.1 - 1.6e-10 40.4 10.8 2.6e-10 39.7 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UCH PF00443.24 KUM59373.1 - 8.2e-10 38.2 0.0 1.5e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 KUM59373.1 - 8.7e-07 29.2 0.0 0.03 14.5 0.0 2.6 2 0 0 2 2 2 2 MATH domain zf-C3HC4_2 PF13923.1 KUM59373.1 - 0.025 14.5 13.2 0.049 13.6 9.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KUM59373.1 - 1.3 8.8 11.9 2.3 8.0 8.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain SMI1_KNR4 PF09346.5 KUM59374.1 - 0.007 16.3 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) PAD_porph PF04371.10 KUM59375.1 - 1.6e-73 247.6 0.0 2.1e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Orn_Arg_deC_N PF02784.11 KUM59376.1 - 3.2e-58 196.8 0.0 4.1e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KUM59376.1 - 5.5e-26 90.5 0.1 9.5e-26 89.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.15 KUM59376.1 - 0.0003 20.4 0.0 0.00042 19.9 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain CinA PF02464.12 KUM59376.1 - 0.096 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Competence-damaged protein Opi1 PF08618.5 KUM59377.1 - 2e-97 326.8 0.1 1.4e-55 188.9 1.1 3.6 1 1 2 3 3 3 3 Transcription factor Opi1 Perilipin PF03036.11 KUM59377.1 - 0.065 12.0 0.6 5.2 5.8 0.0 2.3 2 0 0 2 2 2 0 Perilipin family RdRP PF05183.7 KUM59378.1 - 2.5e-129 432.6 0.0 4e-129 431.9 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase WXG100 PF06013.7 KUM59378.1 - 0.022 14.7 3.6 0.049 13.6 2.5 1.5 1 0 0 1 1 1 0 Proteins of 100 residues with WXG NmrA PF05368.8 KUM59379.1 - 2.1e-29 102.4 0.0 2.7e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KUM59379.1 - 2.2e-13 50.6 0.0 4e-13 49.7 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KUM59379.1 - 1.6e-06 27.3 0.1 2.1e-06 26.9 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KUM59379.1 - 0.00032 20.9 0.0 0.00055 20.2 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 KUM59379.1 - 0.00096 18.8 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 KUM59379.1 - 0.0099 15.9 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 KUM59379.1 - 0.062 13.2 0.2 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.15 KUM59379.1 - 0.17 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF4301 PF14134.1 KUM59379.1 - 0.2 10.1 0.0 0.31 9.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4301) DUF2985 PF11204.3 KUM59380.1 - 1.2e-29 101.9 2.6 2.6e-29 100.8 1.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) GvpK PF05121.7 KUM59380.1 - 0.31 10.8 2.2 0.66 9.8 1.5 1.5 1 0 0 1 1 1 0 Gas vesicle protein K Hydrophobin PF01185.13 KUM59381.1 - 9.5e-15 54.8 7.4 1.3e-14 54.3 5.1 1.2 1 0 0 1 1 1 1 Fungal hydrophobin MFS_1 PF07690.11 KUM59382.1 - 1.4e-41 142.4 31.1 3.6e-38 131.1 15.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KUM59382.1 - 3.9e-05 22.2 21.0 0.0012 17.3 3.9 2.8 1 1 2 3 3 3 2 MFS/sugar transport protein AA_permease PF00324.16 KUM59383.1 - 2.6e-71 240.4 36.1 3.1e-71 240.1 25.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KUM59383.1 - 5.3e-15 54.8 37.5 6.7e-15 54.5 26.0 1.2 1 0 0 1 1 1 1 Amino acid permease ArfGap PF01412.13 KUM59384.1 - 7.6e-32 109.5 0.1 1.4e-31 108.6 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf GTP_EFTU PF00009.22 KUM59385.1 - 1.7e-52 177.6 0.0 2.5e-52 177.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KUM59385.1 - 2.4e-25 88.1 0.0 5.2e-25 87.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 KUM59385.1 - 3.4e-17 62.0 0.1 4.1e-09 36.1 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KUM59385.1 - 3e-05 24.0 0.0 6.5e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DUF2383 PF09537.5 KUM59385.1 - 0.051 13.8 0.0 0.35 11.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) MMR_HSR1 PF01926.18 KUM59385.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Epimerase PF01370.16 KUM59387.1 - 1e-10 41.5 0.1 0.00024 20.6 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KUM59387.1 - 2.6e-06 27.7 0.0 4.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 KUM59387.1 - 2.1e-05 23.9 0.0 3.3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KUM59387.1 - 0.0077 16.2 0.0 0.014 15.4 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KUM59387.1 - 0.018 13.7 0.0 0.45 9.1 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KUM59387.1 - 0.091 11.6 0.0 0.55 9.1 0.0 2.3 2 1 0 2 2 2 0 Male sterility protein Tho2 PF11262.3 KUM59388.1 - 2.1e-93 312.6 0.1 3.5e-93 311.9 0.0 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 KUM59388.1 - 4.6e-30 103.2 0.2 3.6e-29 100.3 0.0 2.4 2 0 0 2 2 2 1 Transcription- and export-related complex subunit Vps5 PF09325.5 KUM59389.1 - 1.6e-17 63.5 0.7 2.5e-17 62.9 0.5 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KUM59389.1 - 7.2e-10 38.6 0.0 1.5e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 PX domain GFA PF04828.9 KUM59390.1 - 1.7e-18 66.3 0.1 2.4e-18 65.8 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 KUM59390.1 - 0.017 14.3 0.1 0.049 12.8 0.1 1.8 1 0 0 1 1 1 0 zinc-ribbon domain NOB1_Zn_bind PF08772.6 KUM59390.1 - 0.068 13.0 0.1 0.068 13.0 0.1 1.8 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_2 PF13240.1 KUM59390.1 - 0.093 12.2 0.3 0.093 12.2 0.2 2.0 2 0 0 2 2 2 0 zinc-ribbon domain NST1 PF13945.1 KUM59391.1 - 0.52 10.3 4.9 0.47 10.5 3.4 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator BLVR PF06375.6 KUM59391.1 - 1.1 9.0 5.8 1.1 9.0 4.0 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) RRM_1 PF00076.17 KUM59392.1 - 2.3e-31 107.2 0.2 1.3e-14 53.5 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM59392.1 - 5.9e-22 77.4 0.0 4.5e-11 42.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM59392.1 - 5.4e-10 38.9 0.0 0.00093 19.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 KUM59392.1 - 0.092 12.4 0.1 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 DbpA RNA binding domain API5 PF05918.6 KUM59392.1 - 0.25 9.8 2.6 0.39 9.1 1.8 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Inp1 PF12634.2 KUM59393.1 - 1.8e-35 121.7 0.0 4e-35 120.6 0.0 1.6 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 SRP14 PF02290.10 KUM59394.1 - 9.2e-22 76.7 0.0 2.1e-21 75.6 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle 14kD protein FmdA_AmdA PF03069.10 KUM59395.1 - 8.4e-158 524.8 0.0 9.6e-158 524.6 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Mannosyl_trans PF05007.8 KUM59396.1 - 0.00042 20.0 0.4 0.0009 18.9 0.3 1.5 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) EI24 PF07264.6 KUM59396.1 - 0.0028 17.1 7.1 0.0028 17.1 4.9 3.4 1 1 0 3 3 3 1 Etoposide-induced protein 2.4 (EI24) SNN_cytoplasm PF09051.5 KUM59396.1 - 0.15 11.7 0.3 0.29 10.9 0.2 1.4 1 0 0 1 1 1 0 Stannin cytoplasmic DUF3149 PF11346.3 KUM59396.1 - 7.8 6.1 7.9 2.6 7.6 2.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) Filament PF00038.16 KUM59397.1 - 0.0031 17.0 1.6 0.0031 17.0 1.1 1.8 1 1 0 2 2 2 1 Intermediate filament protein RPW8 PF05659.6 KUM59397.1 - 0.0032 17.0 3.9 0.0048 16.4 2.7 1.2 1 0 0 1 1 1 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 GrpE PF01025.14 KUM59397.1 - 0.0063 16.0 2.1 0.014 14.9 1.4 1.6 1 1 0 1 1 1 1 GrpE PspA_IM30 PF04012.7 KUM59397.1 - 0.013 14.8 1.4 0.24 10.7 0.2 2.3 1 1 1 2 2 2 0 PspA/IM30 family Med9 PF07544.8 KUM59397.1 - 0.014 15.1 0.8 0.047 13.4 0.2 2.0 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Herpes_U30 PF04523.8 KUM59397.1 - 0.016 12.6 0.4 0.018 12.5 0.3 1.1 1 0 0 1 1 1 0 Herpes virus tegument protein U30 DNase_II PF03265.10 KUM59397.1 - 0.016 14.2 1.9 0.022 13.7 1.3 1.2 1 0 0 1 1 1 0 Deoxyribonuclease II Prominin PF05478.6 KUM59397.1 - 0.022 12.3 1.0 0.03 11.8 0.7 1.1 1 0 0 1 1 1 0 Prominin V-SNARE_C PF12352.3 KUM59397.1 - 0.022 14.7 2.5 4.2 7.5 0.1 3.0 2 1 1 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus TMF_DNA_bd PF12329.3 KUM59397.1 - 0.035 13.8 1.2 0.083 12.7 0.8 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF948 PF06103.6 KUM59397.1 - 0.037 13.8 1.4 0.92 9.4 0.1 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) YlbD_coat PF14071.1 KUM59397.1 - 0.052 13.6 7.0 0.16 12.0 0.7 2.5 1 1 1 2 2 2 0 Putative coat protein Baculo_PEP_C PF04513.7 KUM59397.1 - 0.053 13.3 1.0 0.13 12.0 0.6 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 KUM59397.1 - 0.058 12.9 6.4 0.17 11.4 4.4 1.8 1 1 0 1 1 1 0 IncA protein Rad9 PF04139.8 KUM59397.1 - 0.072 12.2 0.6 0.21 10.6 0.5 1.8 1 1 0 1 1 1 0 Rad9 DegS PF05384.6 KUM59397.1 - 0.083 12.0 4.0 0.13 11.4 1.8 2.0 1 1 1 2 2 2 0 Sensor protein DegS Tho2 PF11262.3 KUM59397.1 - 0.093 11.7 1.6 0.16 10.9 0.4 1.7 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 TRAUB PF08164.7 KUM59397.1 - 0.13 12.4 0.6 0.28 11.3 0.4 1.5 1 0 0 1 1 1 0 Apoptosis-antagonizing transcription factor, C-terminal SF-assemblin PF06705.6 KUM59397.1 - 0.19 10.8 5.0 0.29 10.2 0.5 2.3 1 1 0 2 2 2 0 SF-assemblin/beta giardin ALIX_LYPXL_bnd PF13949.1 KUM59397.1 - 0.22 10.4 6.8 0.13 11.1 0.9 2.1 1 1 0 2 2 2 0 ALIX V-shaped domain binding to HIV NPV_P10 PF05531.7 KUM59397.1 - 0.25 11.6 5.9 46 4.3 4.1 2.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF342 PF03961.8 KUM59397.1 - 0.29 9.5 2.7 0.45 8.8 1.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) COG2 PF06148.6 KUM59397.1 - 0.29 11.0 3.6 2.8 7.7 2.5 2.4 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Fzo_mitofusin PF04799.8 KUM59397.1 - 0.45 9.8 4.9 2.8 7.3 0.7 3.2 2 1 2 4 4 4 0 fzo-like conserved region Cytochrom_B562 PF07361.6 KUM59397.1 - 0.52 10.7 7.5 0.92 9.9 1.3 2.9 2 1 1 3 3 3 0 Cytochrome b562 ApoLp-III PF07464.6 KUM59397.1 - 0.59 10.1 7.3 0.6 10.1 3.6 1.9 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF904 PF06005.7 KUM59397.1 - 0.68 10.2 6.1 2.4 8.5 4.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Baculo_p24 PF05073.7 KUM59397.1 - 1.1 8.8 5.0 1.3 8.5 0.7 2.1 1 1 1 2 2 2 0 Baculovirus P24 capsid protein TBPIP PF07106.8 KUM59397.1 - 1.3 8.5 8.7 1.4 8.4 2.2 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) SlyX PF04102.7 KUM59397.1 - 1.5 9.2 6.6 4.1 7.8 0.3 3.0 2 1 1 3 3 3 0 SlyX Syntaxin-6_N PF09177.6 KUM59397.1 - 1.7 9.1 7.4 8.8 6.8 0.9 2.9 1 1 2 3 3 3 0 Syntaxin 6, N-terminal WXG100 PF06013.7 KUM59397.1 - 2 8.4 6.7 32 4.6 0.0 3.6 2 1 1 3 3 3 0 Proteins of 100 residues with WXG BLOC1_2 PF10046.4 KUM59397.1 - 2.5 8.2 5.7 0.73 10.0 0.5 2.3 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prefoldin PF02996.12 KUM59397.1 - 3.3 7.3 6.1 26 4.4 0.5 3.0 1 1 2 3 3 3 0 Prefoldin subunit Spc24 PF08286.6 KUM59397.1 - 3.8 7.2 8.1 91 2.7 5.6 2.7 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 FlaC_arch PF05377.6 KUM59397.1 - 5.5 6.9 7.6 26 4.7 0.1 3.4 3 1 1 4 4 3 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.15 KUM59397.1 - 6.6 6.5 8.6 28 4.5 2.5 3.6 2 1 1 3 3 3 0 Prefoldin subunit Tyr_Deacylase PF02580.11 KUM59398.1 - 5.2e-48 162.7 0.0 6.1e-48 162.4 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Pro_isomerase PF00160.16 KUM59399.1 - 3.3e-46 157.3 1.0 4.9e-46 156.7 0.7 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 KUM59399.1 - 4.7e-08 32.5 5.7 0.0035 16.9 0.7 2.4 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 KUM59399.1 - 5.2e-05 22.6 1.1 5.2e-05 22.6 0.7 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KUM59399.1 - 0.00012 21.6 10.0 0.00036 20.2 1.3 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KUM59399.1 - 0.00029 20.7 4.1 0.0038 17.1 2.9 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KUM59399.1 - 0.013 16.0 1.6 0.14 12.9 0.6 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KUM59399.1 - 0.014 15.1 1.0 0.014 15.1 0.7 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 KUM59399.1 - 0.026 15.1 10.0 0.29 11.8 5.7 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KUM59399.1 - 8.8 7.0 8.6 1.6 9.3 0.3 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat MIF4G PF02854.14 KUM59400.1 - 2.6e-19 69.4 1.0 3.9e-19 68.9 0.1 1.8 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 KUM59400.1 - 4.3e-17 61.8 0.1 3.5e-16 58.9 0.0 2.5 2 0 0 2 2 2 1 MA3 domain Not3 PF04065.10 KUM59401.1 - 5.5e-95 317.0 18.1 7.5e-95 316.6 12.6 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 KUM59401.1 - 5.2e-43 146.1 10.6 1.1e-42 145.0 7.4 1.6 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Snapin_Pallidin PF14712.1 KUM59401.1 - 0.00056 20.1 6.8 0.014 15.6 0.2 2.6 2 1 0 2 2 2 2 Snapin/Pallidin Poty_PP PF08440.5 KUM59401.1 - 0.0031 16.6 1.0 0.0063 15.6 0.7 1.5 1 0 0 1 1 1 1 Potyviridae polyprotein Cep57_MT_bd PF06657.8 KUM59401.1 - 0.0057 16.5 6.4 0.028 14.3 0.2 2.7 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 DUF2373 PF10180.4 KUM59401.1 - 0.0084 15.6 3.0 0.023 14.2 2.1 1.7 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) DUF1192 PF06698.6 KUM59401.1 - 0.058 13.2 2.1 0.17 11.7 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Syntaxin_2 PF14523.1 KUM59401.1 - 0.34 10.9 7.2 0.1 12.6 1.5 2.4 2 0 0 2 2 2 0 Syntaxin-like protein Syntaxin PF00804.20 KUM59401.1 - 0.48 10.6 9.7 1.3 9.1 3.2 3.1 3 0 0 3 3 3 0 Syntaxin DUF904 PF06005.7 KUM59401.1 - 2.4 8.4 8.6 1.1 9.5 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF2951 PF11166.3 KUM59401.1 - 3.9 7.3 8.1 1.6 8.6 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) zf-C2H2_4 PF13894.1 KUM59402.1 - 1.7e-06 27.9 13.7 1.5e-05 24.9 0.6 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KUM59402.1 - 1.8e-05 24.7 17.7 2.7e-05 24.2 1.4 3.4 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KUM59402.1 - 0.0076 16.3 1.3 0.014 15.5 0.3 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KUM59402.1 - 1.3 9.0 10.5 0.4 10.6 0.7 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KUM59402.1 - 1.5 9.2 16.1 0.64 10.4 0.7 3.5 3 0 0 3 3 3 0 Zinc-finger double domain Sugar_tr PF00083.19 KUM59403.1 - 9.8e-82 274.9 22.5 1.1e-81 274.6 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM59403.1 - 5e-22 78.1 49.0 1.9e-16 59.7 14.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KUM59403.1 - 0.081 12.9 8.9 3.2 7.8 0.4 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) OATP PF03137.15 KUM59403.1 - 3.8 5.4 9.2 0.37 8.7 0.0 2.8 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 KUM59404.1 - 4.2e-43 147.4 22.4 4.2e-43 147.4 15.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM59404.1 - 3e-10 39.2 9.9 3e-10 39.2 6.9 1.7 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KUM59404.1 - 5e-06 25.0 4.3 7.6e-06 24.4 3.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4131 PF13567.1 KUM59404.1 - 0.0028 17.1 0.2 0.0028 17.1 0.1 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF4131) Bac_transf PF02397.11 KUM59404.1 - 0.11 11.6 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial sugar transferase Pyr_redox_dim PF02852.17 KUM59405.1 - 2.7e-40 136.8 0.2 2.7e-40 136.8 0.1 2.3 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 KUM59405.1 - 1.8e-35 122.6 19.9 1.4e-34 119.7 13.8 3.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KUM59405.1 - 7.5e-21 74.3 10.6 2.2e-19 69.6 0.8 3.3 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KUM59405.1 - 6.6e-11 41.9 0.8 6.6e-11 41.9 0.5 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KUM59405.1 - 3.8e-09 36.4 5.4 0.00015 21.6 0.5 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KUM59405.1 - 3.6e-08 32.6 14.0 8.3e-07 28.1 3.9 3.0 2 2 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KUM59405.1 - 3.5e-07 29.4 3.8 3.5e-07 29.4 2.6 3.2 3 1 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.1 KUM59405.1 - 5.3e-07 29.9 1.9 4e-05 23.7 0.5 2.5 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KUM59405.1 - 6.1e-07 28.6 17.6 0.00029 19.8 0.4 4.2 3 1 0 4 4 4 3 FAD dependent oxidoreductase K_oxygenase PF13434.1 KUM59405.1 - 2.7e-06 26.5 0.8 0.015 14.2 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 KUM59405.1 - 6.2e-05 22.6 3.5 0.0058 16.2 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 KUM59405.1 - 0.00089 18.4 2.4 0.00089 18.4 1.6 2.5 1 1 1 2 2 2 1 Thi4 family HI0933_like PF03486.9 KUM59405.1 - 0.0012 17.3 1.9 0.0012 17.3 1.3 3.8 4 0 0 4 4 4 1 HI0933-like protein Lycopene_cycl PF05834.7 KUM59405.1 - 0.0075 15.2 0.9 0.059 12.2 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein 3HCDH_N PF02737.13 KUM59405.1 - 0.016 14.8 1.7 0.016 14.8 1.1 2.5 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KUM59405.1 - 0.018 14.1 8.1 0.48 9.4 0.5 2.8 2 1 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.1 KUM59405.1 - 0.27 11.5 3.7 1.1 9.5 0.3 3.1 3 1 0 3 3 3 0 Putative NAD(P)-binding Trp_halogenase PF04820.9 KUM59405.1 - 4.7 5.7 7.5 0.96 7.9 0.5 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Asparaginase PF00710.15 KUM59406.1 - 5.6e-68 229.1 3.5 6.5e-68 228.9 2.4 1.0 1 0 0 1 1 1 1 Asparaginase Glyco_hydro_16 PF00722.16 KUM59408.1 - 1.2e-07 31.2 0.2 1.8e-07 30.6 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1945 PF09178.5 KUM59409.1 - 0.13 12.1 0.2 0.27 11.1 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1945) WD40 PF00400.27 KUM59410.1 - 5.3e-53 175.1 19.8 2.6e-09 36.6 0.4 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 KUM59410.1 - 1.5e-10 39.9 9.4 0.001 17.2 0.2 5.3 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KUM59410.1 - 0.00041 19.2 0.5 0.02 13.6 0.0 3.2 2 1 1 3 3 3 1 Nup133 N terminal like PQQ_2 PF13360.1 KUM59410.1 - 0.0071 15.8 5.5 0.48 9.8 1.3 3.8 2 1 0 2 2 2 1 PQQ-like domain Pkinase PF00069.20 KUM59411.1 - 3.7e-20 72.1 0.0 1.3e-19 70.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM59411.1 - 7.8e-13 48.0 0.0 5.5e-09 35.4 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KUM59411.1 - 0.0061 16.3 0.1 0.55 9.9 0.3 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 KUM59411.1 - 0.092 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family zf-Tim10_DDP PF02953.10 KUM59412.1 - 7.2e-22 76.4 1.2 9.3e-22 76.0 0.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger eIF3_subunit PF08597.5 KUM59412.1 - 0.16 11.5 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Lectin_leg-like PF03388.8 KUM59413.1 - 2.4e-63 213.3 0.0 3.2e-63 212.9 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family BRF1 PF07741.8 KUM59414.1 - 1.1 9.5 15.9 1.3 9.3 4.0 2.6 2 1 0 2 2 2 0 Brf1-like TBP-binding domain PRCC PF10253.4 KUM59416.1 - 1.6e-41 142.9 0.5 1.6e-41 142.9 0.4 3.0 3 1 1 4 4 4 1 Mitotic checkpoint regulator, MAD2B-interacting PAT1 PF09770.4 KUM59416.1 - 0.0047 15.2 15.1 0.0061 14.8 10.4 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Pkinase PF00069.20 KUM59417.1 - 1.8e-67 227.2 0.0 2.1e-67 226.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM59417.1 - 4.3e-37 127.5 0.0 5.7e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM59417.1 - 3.1e-06 26.3 0.0 6.3e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KUM59417.1 - 0.015 15.0 0.1 0.048 13.3 0.0 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Mito_carr PF00153.22 KUM59418.1 - 1.9e-47 158.9 6.0 1.6e-16 59.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF155 PF02582.9 KUM59420.1 - 2.2e-53 180.7 0.8 3e-53 180.3 0.1 1.6 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 DUF2205 PF10224.4 KUM59421.1 - 0.082 12.4 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) CTK3 PF12243.3 KUM59422.1 - 7.7e-58 194.0 0.4 1.2e-57 193.4 0.3 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 KUM59422.1 - 1.5e-18 66.5 9.1 4e-18 65.1 6.3 1.8 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus MAM33 PF02330.11 KUM59422.1 - 0.0017 18.1 0.2 0.0032 17.2 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial glycoprotein U3_snoRNA_assoc PF08297.6 KUM59423.1 - 4.9e-15 55.5 0.9 4.9e-15 55.5 0.6 3.2 3 1 0 3 3 3 2 U3 snoRNA associated Cwf_Cwc_15 PF04889.7 KUM59423.1 - 0.16 11.6 18.7 0.29 10.8 13.0 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RRP14 PF15459.1 KUM59423.1 - 0.57 10.2 15.3 0.11 12.6 5.0 2.7 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 Macoilin PF09726.4 KUM59423.1 - 5.4 5.1 12.3 8.1 4.5 8.6 1.2 1 0 0 1 1 1 0 Transmembrane protein Parvo_coat PF00740.13 KUM59423.1 - 8.5 5.1 7.9 11 4.7 5.5 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 AAA_5 PF07728.9 KUM59424.1 - 8.1e-130 427.3 0.2 4.2e-22 78.3 0.0 9.7 8 1 1 9 9 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KUM59424.1 - 3e-29 101.2 0.0 9e-11 41.4 0.0 7.3 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 KUM59424.1 - 4.3e-28 98.1 0.0 0.00023 21.3 0.0 7.0 6 0 0 6 6 6 6 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KUM59424.1 - 1.2e-25 90.1 0.0 0.00013 21.8 0.0 7.7 6 1 0 6 6 6 5 AAA domain AAA_16 PF13191.1 KUM59424.1 - 1.6e-21 77.1 8.6 0.001 19.1 0.0 8.5 7 0 0 7 7 6 4 AAA ATPase domain AAA_22 PF13401.1 KUM59424.1 - 2.7e-21 76.0 1.0 0.013 15.6 0.0 8.6 8 0 0 8 8 7 4 AAA domain AAA_14 PF13173.1 KUM59424.1 - 2.2e-20 72.8 0.0 0.00042 20.2 0.0 7.9 8 0 0 8 8 7 4 AAA domain AAA_17 PF13207.1 KUM59424.1 - 7.4e-20 71.9 1.0 0.0029 18.4 0.0 7.6 7 0 0 7 7 6 3 AAA domain AAA_18 PF13238.1 KUM59424.1 - 4.1e-18 65.9 0.0 0.012 15.9 0.0 7.4 6 0 0 6 6 6 4 AAA domain ABC_tran PF00005.22 KUM59424.1 - 2.1e-15 57.1 2.6 0.0035 17.6 0.0 7.2 7 0 0 7 7 6 3 ABC transporter Zeta_toxin PF06414.7 KUM59424.1 - 2.7e-15 56.0 2.6 0.065 12.3 0.0 7.7 7 1 0 7 7 6 4 Zeta toxin Sigma54_activat PF00158.21 KUM59424.1 - 8.1e-14 51.4 0.0 0.013 14.9 0.0 5.9 6 0 0 6 6 6 3 Sigma-54 interaction domain UPF0079 PF02367.12 KUM59424.1 - 3.4e-13 49.3 4.0 0.17 11.5 0.0 6.5 6 0 0 6 6 6 3 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 KUM59424.1 - 5.5e-13 48.5 0.4 1.8 7.6 0.0 8.8 9 0 0 9 9 9 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KUM59424.1 - 1.7e-12 47.4 0.6 0.76 9.9 0.0 6.8 6 0 0 6 6 6 2 RNA helicase MobB PF03205.9 KUM59424.1 - 3.7e-12 46.1 2.6 0.34 10.6 0.0 6.6 6 0 0 6 6 6 2 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 KUM59424.1 - 4.4e-12 45.8 2.5 0.044 13.2 0.0 6.0 6 0 0 6 6 5 2 SRP54-type protein, GTPase domain Sigma54_activ_2 PF14532.1 KUM59424.1 - 4.5e-12 46.1 0.2 0.024 14.6 0.0 5.9 5 0 0 5 5 5 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 KUM59424.1 - 7.9e-12 45.3 2.1 1.4 8.5 0.0 6.5 7 0 0 7 7 6 3 Archaeal ATPase NACHT PF05729.7 KUM59424.1 - 1.5e-11 44.2 9.0 0.063 12.9 0.1 6.3 6 0 0 6 6 5 4 NACHT domain AAA_28 PF13521.1 KUM59424.1 - 1.9e-11 44.1 4.6 0.15 12.0 0.1 6.9 6 0 0 6 6 6 2 AAA domain DUF258 PF03193.11 KUM59424.1 - 2.7e-11 42.9 1.8 0.077 12.1 0.0 6.2 6 0 0 6 6 6 2 Protein of unknown function, DUF258 Miro PF08477.8 KUM59424.1 - 6e-11 42.8 0.9 2.4 8.6 0.0 6.7 6 0 0 6 6 6 1 Miro-like protein AAA_19 PF13245.1 KUM59424.1 - 6e-11 41.9 5.2 0.28 10.9 0.1 6.5 6 0 0 6 6 6 3 Part of AAA domain MMR_HSR1 PF01926.18 KUM59424.1 - 3.6e-10 39.8 0.2 0.0095 15.8 0.0 6.6 6 0 0 6 6 6 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 KUM59424.1 - 4.7e-10 39.1 2.8 0.11 11.9 0.0 6.1 6 0 0 6 6 6 3 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 KUM59424.1 - 5e-10 38.7 1.2 0.56 9.7 0.0 6.3 6 0 0 6 6 6 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KUM59424.1 - 6.8e-10 38.6 2.9 0.91 8.8 0.0 6.5 6 0 0 6 6 5 1 AAA domain T2SE PF00437.15 KUM59424.1 - 2.1e-09 36.6 3.0 0.58 9.0 0.0 6.1 6 0 0 6 6 6 2 Type II/IV secretion system protein RuvB_N PF05496.7 KUM59424.1 - 8e-09 34.8 8.2 0.47 9.4 0.0 7.6 8 1 0 8 8 8 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 KUM59424.1 - 4.3e-08 32.3 1.4 0.54 9.1 0.0 5.6 6 0 0 6 6 6 2 Protein of unknown function (DUF815) NTPase_1 PF03266.10 KUM59424.1 - 7.4e-07 29.0 5.5 1.5 8.4 0.0 5.8 5 0 0 5 5 5 2 NTPase IstB_IS21 PF01695.12 KUM59424.1 - 9.4e-07 28.4 0.1 1.9 7.9 0.0 5.4 5 0 0 5 5 5 1 IstB-like ATP binding protein cobW PF02492.14 KUM59424.1 - 1.5e-06 27.8 5.7 2.4 7.5 0.0 6.4 6 0 0 6 6 6 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.2 KUM59424.1 - 2.1e-06 27.0 0.7 0.22 10.6 0.0 4.9 5 0 0 5 5 5 1 P-loop containing dynein motor region D3 Viral_helicase1 PF01443.13 KUM59424.1 - 2.1e-06 27.4 0.1 0.26 10.7 0.0 5.1 5 0 0 5 5 5 1 Viral (Superfamily 1) RNA helicase ATP_bind_1 PF03029.12 KUM59424.1 - 3.6e-06 26.6 2.9 2.7 7.4 0.0 6.0 6 0 0 6 6 6 1 Conserved hypothetical ATP binding protein Bac_DnaA PF00308.13 KUM59424.1 - 6.5e-06 25.9 0.1 0.91 9.1 0.0 4.2 4 0 0 4 4 3 1 Bacterial dnaA protein SRPRB PF09439.5 KUM59424.1 - 8.3e-06 25.1 2.7 1.9 7.6 0.0 6.0 6 0 0 6 6 6 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 KUM59424.1 - 4e-05 23.2 0.0 10 5.6 0.0 5.1 5 0 0 5 5 5 0 AAA domain PhoH PF02562.11 KUM59424.1 - 7e-05 22.1 0.2 1.6 7.9 0.0 4.4 4 0 0 4 4 4 1 PhoH-like protein Rad17 PF03215.10 KUM59424.1 - 0.00011 21.0 1.0 0.68 8.5 0.0 4.5 5 0 0 5 5 5 1 Rad17 cell cycle checkpoint protein MCM PF00493.18 KUM59424.1 - 0.00012 21.0 0.4 1.2 7.8 0.0 4.4 5 0 0 5 5 5 1 MCM2/3/5 family NB-ARC PF00931.17 KUM59424.1 - 0.00013 20.9 0.7 4.9 5.9 0.0 4.8 4 0 0 4 4 4 0 NB-ARC domain TIP49 PF06068.8 KUM59424.1 - 0.00042 19.1 1.5 0.65 8.6 0.0 4.7 5 0 0 5 5 5 1 TIP49 C-terminus KTI12 PF08433.5 KUM59424.1 - 0.0023 17.1 0.1 1.9 7.6 0.0 4.1 4 0 0 4 4 3 1 Chromatin associated protein KTI12 KaiC PF06745.8 KUM59424.1 - 0.0025 16.9 0.9 23 4.0 0.0 4.9 5 0 0 5 5 5 0 KaiC CbiA PF01656.18 KUM59424.1 - 0.0038 16.6 0.2 0.49 9.7 0.1 3.1 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain FeoB_N PF02421.13 KUM59424.1 - 0.0063 15.7 5.4 0.75 9.0 0.0 5.1 6 0 0 6 6 5 1 Ferrous iron transport protein B ResIII PF04851.10 KUM59424.1 - 0.019 14.7 14.1 0.11 12.2 0.0 5.5 7 0 0 7 7 4 0 Type III restriction enzyme, res subunit ArgK PF03308.11 KUM59424.1 - 0.032 13.0 1.1 5.1 5.7 0.1 3.3 3 0 0 3 3 3 0 ArgK protein AAA_6 PF12774.2 KUM59424.1 - 0.042 13.3 0.0 32 3.9 0.0 4.3 6 0 0 6 6 3 0 Hydrolytic ATP binding site of dynein motor region D1 AAA_15 PF13175.1 KUM59424.1 - 0.091 11.7 0.2 15 4.5 0.0 3.8 5 0 0 5 5 4 0 AAA ATPase domain Voltage_CLC PF00654.15 KUM59425.1 - 1.5e-91 307.0 25.9 1.5e-91 307.0 18.0 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KUM59425.1 - 8.4e-07 28.6 0.0 0.0023 17.6 0.0 2.5 2 0 0 2 2 2 2 CBS domain DUF3716 PF12511.3 KUM59426.1 - 1.5e-14 53.2 9.4 2.4e-14 52.6 6.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF3268 PF11672.3 KUM59426.1 - 0.07 13.2 1.5 0.16 12.0 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) Zn_clus PF00172.13 KUM59427.1 - 2.3e-08 33.8 7.2 5e-08 32.7 5.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KUM59427.1 - 2.4e-05 23.0 0.0 7.6e-05 21.4 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain E_Pc_C PF06752.7 KUM59427.1 - 0.025 14.1 0.7 0.044 13.2 0.5 1.3 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Actin PF00022.14 KUM59428.1 - 4.2e-132 440.2 0.0 4.8e-132 440.1 0.0 1.0 1 0 0 1 1 1 1 Actin Glyco_tran_28_C PF04101.11 KUM59429.1 - 1.7e-20 73.3 0.1 3.8e-20 72.2 0.1 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DUF3602 PF12223.3 KUM59430.1 - 1e-18 67.4 6.7 1.8e-13 50.6 0.8 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) Pet127 PF08634.5 KUM59432.1 - 0.13 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial protein Pet127 AAA PF00004.24 KUM59433.1 - 3.8e-25 88.5 0.0 1.2e-13 51.4 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KUM59433.1 - 4.2e-06 26.9 1.6 0.057 13.5 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KUM59433.1 - 9.6e-06 25.3 0.1 0.047 13.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KUM59433.1 - 1.2e-05 24.9 0.2 0.11 12.2 0.0 3.1 3 0 0 3 3 3 2 Part of AAA domain IstB_IS21 PF01695.12 KUM59433.1 - 3.2e-05 23.4 0.0 0.46 9.8 0.0 3.4 3 0 0 3 3 3 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 KUM59433.1 - 0.00014 21.1 0.0 0.13 11.3 0.0 2.8 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI MAP7 PF05672.6 KUM59433.1 - 0.00035 20.0 28.6 0.00063 19.1 19.8 1.3 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family AAA_24 PF13479.1 KUM59433.1 - 0.00068 19.2 0.8 0.63 9.5 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_11 PF13086.1 KUM59433.1 - 0.0013 18.3 4.6 1.4 8.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain VirE PF05272.6 KUM59433.1 - 0.0019 17.7 0.2 0.017 14.5 0.0 2.4 2 1 0 2 2 2 1 Virulence-associated protein E Torsin PF06309.6 KUM59433.1 - 0.002 17.9 0.0 1.3 8.9 0.0 2.7 3 0 0 3 3 2 1 Torsin RuvB_N PF05496.7 KUM59433.1 - 0.0022 17.0 0.0 0.7 8.8 0.0 2.7 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KUM59433.1 - 0.0046 17.7 9.7 0.15 12.8 0.0 3.8 3 2 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KUM59433.1 - 0.0074 16.2 7.3 0.25 11.3 0.0 3.7 3 1 0 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.17 KUM59433.1 - 0.0084 16.2 0.1 1.8 8.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.1 KUM59433.1 - 0.63 10.3 9.4 5.8 7.2 0.1 3.9 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 KUM59433.1 - 0.66 9.8 7.0 1.1 9.1 0.0 3.5 4 0 0 4 4 4 0 AAA domain APG6 PF04111.7 KUM59433.1 - 0.78 8.7 16.0 1.6 7.7 11.1 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 zf-U1 PF06220.7 KUM59434.1 - 7.2e-07 28.6 0.8 9.5e-07 28.2 0.5 1.2 1 0 0 1 1 1 1 U1 zinc finger MFS_1 PF07690.11 KUM59436.1 - 9.8e-16 57.3 18.6 2.5e-15 56.0 6.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldedh PF00171.17 KUM59437.1 - 2.1e-78 263.7 0.0 2.5e-78 263.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Adap_comp_sub PF00928.16 KUM59438.1 - 7.7e-53 179.2 0.1 9e-52 175.7 0.1 2.4 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KUM59438.1 - 5.7e-05 22.8 0.1 9.4e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain NST1 PF13945.1 KUM59438.1 - 0.016 15.2 2.9 0.026 14.6 2.0 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Mitofilin PF09731.4 KUM59438.1 - 0.14 10.7 2.1 0.2 10.2 1.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein BLVR PF06375.6 KUM59438.1 - 0.18 11.6 6.6 0.35 10.6 4.6 1.4 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) SPT6_acidic PF14632.1 KUM59438.1 - 2.3 8.4 7.2 4.2 7.5 5.0 1.3 1 0 0 1 1 1 0 Acidic N-terminal SPT6 DUF2413 PF10310.4 KUM59438.1 - 6.1 5.5 7.2 5.1 5.7 3.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) DUF4588 PF15251.1 KUM59439.1 - 0.016 15.2 14.2 0.15 12.0 9.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4588) DUF4536 PF15055.1 KUM59440.1 - 0.00085 19.3 0.5 0.0031 17.5 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4536) SpoU_methylase PF00588.14 KUM59441.1 - 2.7e-25 88.8 0.1 7e-24 84.3 0.0 2.5 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 KUM59441.1 - 2e-06 27.8 0.0 4.2e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding CCDC74_C PF14917.1 KUM59441.1 - 0.071 13.1 0.1 4.7 7.2 0.1 2.6 2 0 0 2 2 2 0 Coiled coil protein 74, C terminal ADH_zinc_N PF00107.21 KUM59442.1 - 9.2e-24 83.4 1.3 1.6e-23 82.7 0.9 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM59442.1 - 8.9e-21 73.6 0.2 1.9e-20 72.6 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KUM59442.1 - 6.6e-05 23.7 0.0 0.00017 22.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase IlvN PF07991.7 KUM59442.1 - 0.085 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain AlaDh_PNT_C PF01262.16 KUM59442.1 - 0.09 12.3 0.3 0.17 11.4 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Asp PF00026.18 KUM59443.1 - 2.2e-65 220.9 3.5 2.6e-65 220.7 2.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KUM59443.1 - 1e-06 28.8 0.0 8.4e-06 25.8 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KUM59443.1 - 0.00039 20.8 2.1 0.09 13.2 0.5 3.0 2 1 0 2 2 2 2 Aspartyl protease SNF2_N PF00176.18 KUM59444.1 - 1.2e-83 280.3 0.3 1.8e-83 279.7 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 KUM59444.1 - 1e-42 144.5 1.8 1e-42 144.5 1.2 2.2 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 KUM59444.1 - 4.9e-36 123.5 1.7 4.9e-36 123.5 1.1 3.2 2 0 0 2 2 2 1 HAND Helicase_C PF00271.26 KUM59444.1 - 1.7e-14 53.4 0.0 7.4e-14 51.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KUM59444.1 - 2.5e-09 37.2 0.0 1.4e-08 34.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KUM59444.1 - 4.5e-06 26.2 0.0 9.9e-06 25.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 KUM59444.1 - 0.0099 15.3 0.1 0.019 14.3 0.1 1.4 1 0 0 1 1 1 1 DEAD_2 AAA_14 PF13173.1 KUM59444.1 - 0.019 14.8 0.1 0.079 12.8 0.1 2.1 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KUM59444.1 - 0.024 14.7 0.1 0.16 12.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain MRP-S28 PF10213.4 KUM59445.1 - 6.1e-44 149.1 0.1 1.1e-43 148.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein TraI PF07057.6 KUM59447.1 - 2.1 8.3 16.3 3 7.8 3.3 2.5 1 1 1 2 2 2 0 DNA helicase TraI zf-PHD-like PF15446.1 KUM59448.1 - 2.4e-60 202.8 10.5 5.8e-60 201.5 7.3 1.7 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 KUM59448.1 - 2.2e-56 190.8 0.0 3.7e-56 190.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KUM59448.1 - 2.2e-15 56.2 0.0 7.7e-15 54.5 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KUM59448.1 - 3.1e-14 52.4 1.7 7e-14 51.3 1.2 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.24 KUM59448.1 - 1.9e-06 27.4 13.8 0.0022 17.6 4.1 3.7 2 1 1 3 3 3 2 PHD-finger Chromo PF00385.19 KUM59448.1 - 0.0017 17.9 4.6 0.26 10.9 0.1 3.4 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain PHD_2 PF13831.1 KUM59448.1 - 0.87 8.9 13.1 0.59 9.4 4.9 3.2 2 1 1 3 3 3 0 PHD-finger BCAS2 PF05700.6 KUM59449.1 - 5.6e-54 182.9 4.0 6.1e-54 182.8 2.7 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Ceramidase_alk PF04734.8 KUM59450.1 - 5.2e-275 913.5 0.0 6e-275 913.3 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Cas_CXXC_CXXC PF09706.5 KUM59450.1 - 0.17 12.0 0.0 0.42 10.8 0.0 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_CXXC_CXXC) DUF1691 PF07950.6 KUM59451.1 - 0.4 10.6 12.9 2 8.3 0.5 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1691) HNH PF01844.18 KUM59452.1 - 0.02 14.7 0.6 0.041 13.7 0.4 1.5 1 1 0 1 1 1 0 HNH endonuclease HAD_2 PF13419.1 KUM59453.1 - 4.3e-08 33.5 0.0 5e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase LysM PF01476.15 KUM59453.1 - 0.034 14.0 0.1 11 6.0 0.0 2.4 2 0 0 2 2 2 0 LysM domain DUF3847 PF12958.2 KUM59453.1 - 0.068 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) EI24 PF07264.6 KUM59454.1 - 3e-05 23.5 16.1 4.3e-05 23.0 11.2 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF4231 PF14015.1 KUM59454.1 - 8.6 6.3 8.1 0.86 9.6 2.2 1.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) Zn_clus PF00172.13 KUM59455.1 - 1.6e-08 34.2 9.4 1.6e-08 34.2 6.5 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KUM59455.1 - 0.00015 20.7 0.0 0.00035 19.5 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain GTP_EFTU PF00009.22 KUM59456.1 - 4.6e-35 120.7 2.0 2.2e-34 118.5 1.4 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KUM59456.1 - 9e-27 93.1 1.1 3.9e-26 91.0 0.5 2.1 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KUM59456.1 - 4e-09 36.4 1.0 8.3e-06 25.8 0.1 2.7 2 0 0 2 2 2 2 Elongation factor Tu domain 2 IF2_N PF04760.10 KUM59456.1 - 1.5e-08 34.1 0.0 3.8e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.18 KUM59456.1 - 3.4e-07 30.2 0.0 9.7e-07 28.7 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KUM59456.1 - 0.00062 20.2 0.1 0.0018 18.7 0.1 1.9 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KUM59456.1 - 0.0053 15.9 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KUM59456.1 - 0.016 14.7 0.1 0.055 12.9 0.0 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF3279 PF11682.3 KUM59456.1 - 0.05 13.1 0.5 0.11 12.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3279) DZR PF12773.2 KUM59456.1 - 0.089 12.6 1.5 0.2 11.4 1.0 1.5 1 0 0 1 1 1 0 Double zinc ribbon UPF0547 PF10571.4 KUM59456.1 - 0.093 12.4 3.6 0.18 11.4 2.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 FeoB_N PF02421.13 KUM59456.1 - 0.098 11.9 0.1 0.28 10.4 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B zf-RanBP PF00641.13 KUM59456.1 - 0.55 9.3 4.0 1.1 8.4 2.7 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others zf-C3HC4_3 PF13920.1 KUM59456.1 - 0.59 9.8 2.8 1.3 8.7 2.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Mito_carr PF00153.22 KUM59457.1 - 1.7e-63 210.3 3.7 3.5e-21 74.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein GP38 PF05268.6 KUM59459.1 - 0.72 9.2 15.1 0.75 9.1 10.5 1.1 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 3Beta_HSD PF01073.14 KUM59460.1 - 2e-27 95.6 0.0 7.1e-27 93.8 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KUM59460.1 - 6.3e-13 48.7 0.0 1.1e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KUM59460.1 - 9.5e-12 44.3 0.0 9.2e-10 37.8 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 KUM59460.1 - 3.8e-08 33.5 0.0 1.9e-07 31.2 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KUM59460.1 - 0.00061 18.7 0.0 0.001 18.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KUM59460.1 - 0.0023 16.8 0.0 0.15 10.9 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.20 KUM59460.1 - 0.22 11.4 4.4 3.7 7.4 1.9 3.0 2 1 0 2 2 2 0 short chain dehydrogenase KR PF08659.5 KUM59460.1 - 0.33 10.5 1.5 2.2 7.9 1.0 2.2 1 1 0 1 1 1 0 KR domain Pkinase PF00069.20 KUM59461.1 - 2.6e-39 134.9 0.0 4e-39 134.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM59461.1 - 6.4e-30 104.0 0.0 8.9e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KUM59461.1 - 0.011 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KUM59461.1 - 0.035 13.8 0.0 5.2 6.7 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KUM59461.1 - 0.18 10.7 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Med10 PF09748.4 KUM59462.1 - 5.5e-44 149.0 0.0 6.6e-44 148.8 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.2 KUM59462.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) ILVD_EDD PF00920.16 KUM59463.1 - 1.6e-152 508.5 0.0 1.9e-152 508.3 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family MFS_1 PF07690.11 KUM59464.1 - 6e-21 74.5 54.0 7.4e-19 67.6 36.8 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM59464.1 - 3.7e-05 22.1 24.9 4.8e-05 21.7 17.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Gemini_mov PF01708.11 KUM59464.1 - 0.27 10.7 3.5 11 5.7 0.0 3.4 3 0 0 3 3 3 0 Geminivirus putative movement protein Fungal_trans PF04082.13 KUM59465.1 - 1.2e-24 86.5 1.9 1.9e-24 85.9 1.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fe_dep_repress PF01325.14 KUM59465.1 - 0.041 13.8 0.4 0.071 13.0 0.3 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HpcH_HpaI PF03328.9 KUM59466.1 - 4.1e-29 101.0 0.0 4.6e-29 100.8 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.13 KUM59466.1 - 0.1 11.4 0.0 0.91 8.3 0.0 2.0 2 0 0 2 2 2 0 PEP-utilising enzyme, TIM barrel domain Scs3p PF10261.4 KUM59468.1 - 4.3e-66 222.3 3.3 6.5e-66 221.7 2.3 1.3 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Erythro_esteras PF05139.9 KUM59469.1 - 2.1e-142 474.3 1.2 2.5e-142 474.1 0.9 1.0 1 0 0 1 1 1 1 Erythromycin esterase FAD_binding_2 PF00890.19 KUM59471.1 - 2.7e-85 286.7 0.8 3.3e-85 286.4 0.6 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 KUM59471.1 - 2.5e-18 65.6 2.9 3.4e-18 65.2 0.0 2.7 4 0 0 4 4 4 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 KUM59471.1 - 1.6e-12 46.9 1.9 1.2e-11 44.0 1.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KUM59471.1 - 7.2e-10 39.0 0.0 5.6e-08 32.9 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM59471.1 - 7.8e-09 35.4 0.5 9.4e-08 31.9 0.2 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KUM59471.1 - 5.9e-08 32.2 0.5 1.5e-07 30.9 0.3 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KUM59471.1 - 5.3e-07 28.4 0.9 0.0032 15.9 0.0 3.2 3 0 0 3 3 3 3 HI0933-like protein Thi4 PF01946.12 KUM59471.1 - 1.2e-06 27.7 0.8 0.00066 18.8 0.1 2.8 3 0 0 3 3 3 2 Thi4 family FAD_binding_3 PF01494.14 KUM59471.1 - 4.3e-06 26.0 0.1 7e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KUM59471.1 - 0.0011 19.0 0.7 0.0049 16.9 0.5 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KUM59471.1 - 0.0016 17.5 0.1 1 8.3 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase GIDA PF01134.17 KUM59471.1 - 0.0035 16.2 3.5 0.12 11.1 0.7 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A TORC_M PF12885.2 KUM59471.1 - 0.019 14.7 0.2 0.052 13.3 0.1 1.8 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain Pyr_redox PF00070.22 KUM59471.1 - 0.049 14.0 2.0 2.4 8.6 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Endosulfine PF04667.12 KUM59473.1 - 1.5e-11 44.0 0.0 2.2e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF4220 PF13968.1 KUM59474.1 - 0.1 11.6 1.3 0.19 10.8 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Aldedh PF00171.17 KUM59475.1 - 4.1e-135 450.6 2.0 4.9e-135 450.4 1.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NAD_binding_3 PF03447.11 KUM59475.1 - 0.079 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain PCI PF01399.22 KUM59477.1 - 1.5e-12 47.6 0.0 4.1e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.4 KUM59477.1 - 6.4e-05 22.3 0.2 0.00011 21.5 0.1 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_19 PF14559.1 KUM59477.1 - 0.00046 20.4 1.8 0.0038 17.5 0.3 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat PspA_IM30 PF04012.7 KUM59477.1 - 0.0029 17.0 1.9 0.0053 16.1 1.3 1.4 1 0 0 1 1 1 1 PspA/IM30 family TPR_16 PF13432.1 KUM59477.1 - 0.014 16.0 2.7 2.2 9.0 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KUM59477.1 - 0.059 14.0 5.2 15 6.5 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KUM59477.1 - 0.33 10.9 4.9 0.41 10.6 0.5 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_hydro_17 PF00332.13 KUM59478.1 - 0.0035 16.4 0.8 0.042 12.8 0.2 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 AcetylCoA_hydro PF02550.10 KUM59481.1 - 1e-48 165.7 0.0 1.6e-48 165.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 KUM59481.1 - 1.9e-37 128.3 0.0 3e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain PAH PF02671.16 KUM59482.1 - 1.3e-40 136.7 3.4 4.8e-16 58.1 0.4 3.9 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 KUM59482.1 - 2.4e-40 136.3 0.0 6.3e-40 135.0 0.0 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor ACOX PF01756.14 KUM59482.1 - 0.059 12.7 0.1 3.7 6.8 0.0 2.5 2 0 0 2 2 2 0 Acyl-CoA oxidase WD40 PF00400.27 KUM59484.1 - 4.8e-13 48.4 1.9 0.21 11.5 0.1 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat Serglycin PF04360.7 KUM59484.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Serglycin Glyco_hydro_43 PF04616.9 KUM59486.1 - 4.2e-41 140.9 5.3 4.7e-41 140.7 3.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 FAM176 PF14851.1 KUM59487.1 - 0.053 13.2 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 FAM176 family DUF4190 PF13828.1 KUM59487.1 - 0.28 10.7 3.7 0.16 11.5 1.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4190) Phage_Gp23 PF10669.4 KUM59487.1 - 3.9 7.6 5.5 8 6.5 3.8 1.5 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) NMO PF03060.10 KUM59488.1 - 1.7e-71 241.1 1.1 2e-71 240.8 0.8 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KUM59488.1 - 6.1e-10 38.5 0.8 1.1e-09 37.6 0.5 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KUM59488.1 - 1.2e-07 30.9 1.5 1.8e-07 30.3 1.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KUM59488.1 - 0.00022 20.2 2.1 0.00039 19.4 1.5 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 KUM59488.1 - 0.00076 18.5 0.3 0.0012 17.8 0.2 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Radial_spoke_3 PF06098.6 KUM59488.1 - 0.04 12.9 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 NmrA PF05368.8 KUM59489.1 - 8.9e-21 74.2 0.1 1.2e-20 73.7 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KUM59489.1 - 1.5e-16 60.9 0.2 2.5e-16 60.2 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KUM59489.1 - 2.9e-08 33.0 0.4 4.3e-08 32.5 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KUM59489.1 - 1.3e-06 28.5 0.5 9.5e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 KUM59489.1 - 1.3e-05 25.1 0.6 0.00021 21.1 0.1 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.16 KUM59489.1 - 1.7e-05 24.3 0.3 4.5e-05 22.9 0.0 1.8 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 KUM59489.1 - 4.2e-05 23.8 1.6 0.0011 19.2 0.1 2.4 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 KUM59489.1 - 0.00038 19.2 0.3 0.002 16.8 0.2 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.13 KUM59489.1 - 0.00041 20.0 0.2 0.00098 18.8 0.2 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 KUM59489.1 - 0.0019 18.1 0.3 0.0045 16.9 0.2 1.6 1 0 0 1 1 1 1 TrkA-N domain XdhC_C PF13478.1 KUM59489.1 - 0.058 13.7 0.2 0.18 12.0 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_7 PF13241.1 KUM59489.1 - 0.068 13.4 0.1 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Zn_clus PF00172.13 KUM59492.1 - 2.3e-09 36.9 7.0 4.5e-09 36.0 4.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.2 KUM59493.1 - 4.1e-131 427.6 15.4 6.1e-23 80.9 0.1 9.5 2 2 4 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KUM59493.1 - 7.1e-125 401.1 26.2 1.8e-09 36.9 0.1 18.9 20 0 0 20 20 20 16 Ankyrin repeat Ank_3 PF13606.1 KUM59493.1 - 5.3e-93 295.5 16.0 2.7e-07 30.1 0.0 19.0 19 0 0 19 19 19 15 Ankyrin repeat Ank_5 PF13857.1 KUM59493.1 - 4.3e-91 296.8 19.1 1.5e-10 40.9 0.1 15.0 3 2 13 16 16 16 14 Ankyrin repeats (many copies) Ank_4 PF13637.1 KUM59493.1 - 1.8e-89 292.6 11.9 2e-09 37.7 0.1 12.8 6 2 7 13 13 13 13 Ankyrin repeats (many copies) ZZ PF00569.12 KUM59493.1 - 0.0072 15.8 5.1 0.015 14.8 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type DUF2199 PF09965.4 KUM59494.1 - 0.041 13.7 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) SAF_2 PF13144.1 KUM59496.1 - 0.084 12.3 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 SAF-like HeLo PF14479.1 KUM59500.1 - 2.1e-06 27.6 0.4 3.6e-05 23.6 0.3 2.2 1 1 0 1 1 1 1 Prion-inhibition and propagation NACHT PF05729.7 KUM59500.1 - 0.0077 15.8 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Ribonucleas_3_2 PF11469.3 KUM59500.1 - 0.053 13.7 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease III PPTA PF01239.17 KUM59500.1 - 0.09 12.1 0.0 0.27 10.6 0.0 1.8 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat RNA_helicase PF00910.17 KUM59500.1 - 0.09 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Tim17 PF02466.14 KUM59501.1 - 5.9e-34 116.8 6.3 7.2e-34 116.5 4.4 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Rhodanese PF00581.15 KUM59502.1 - 8.8e-14 51.8 0.0 1e-13 51.6 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_28 PF02636.12 KUM59503.1 - 3e-78 262.6 0.0 4.2e-78 262.2 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PWI PF01480.12 KUM59504.1 - 1.8e-11 43.9 0.3 4.2e-11 42.7 0.2 1.7 1 0 0 1 1 1 1 PWI domain RRM_5 PF13893.1 KUM59504.1 - 0.004 16.9 0.0 0.13 12.1 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KUM59504.1 - 0.0054 16.3 0.0 0.025 14.1 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUKH_6 PF14568.1 KUM59504.1 - 0.028 14.9 0.0 0.065 13.7 0.0 1.5 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall zf-C4H2 PF10146.4 KUM59504.1 - 2.5 8.0 10.9 1.4 8.9 5.3 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein PGI PF00342.14 KUM59505.1 - 9.8e-217 720.1 0.9 1.1e-216 719.9 0.6 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF924 PF06041.6 KUM59505.1 - 0.051 13.3 1.0 0.67 9.6 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF924) Ribosomal_S21 PF01165.15 KUM59507.1 - 1.3e-11 43.6 3.1 1.3e-11 43.6 2.2 1.9 2 0 0 2 2 2 1 Ribosomal protein S21 Pterin_bind PF00809.17 KUM59508.1 - 1.3e-65 220.7 0.0 2e-65 220.0 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 KUM59508.1 - 2.8e-26 91.7 0.2 4.3e-26 91.1 0.1 1.3 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) ArfGap PF01412.13 KUM59509.1 - 3.2e-34 117.2 0.8 5.6e-34 116.4 0.6 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PRCC PF10253.4 KUM59509.1 - 0.015 15.9 5.2 0.015 15.9 3.6 1.9 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting TIM21 PF08294.6 KUM59510.1 - 3.3e-39 133.8 0.0 4.1e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 KUM59510.1 - 6.4e-05 22.4 0.0 0.00016 21.1 0.0 1.6 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 MR_MLE_C PF13378.1 KUM59511.1 - 8e-19 67.6 0.0 2.8e-18 65.9 0.0 2.0 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KUM59511.1 - 3.2e-15 56.4 0.0 1.3e-14 54.4 0.0 2.1 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KUM59511.1 - 1.9e-06 27.8 0.0 4.7e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF464 PF04327.7 KUM59511.1 - 0.043 14.0 0.4 0.1 12.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF464) Surp PF01805.15 KUM59512.1 - 4e-18 64.7 0.0 8e-18 63.8 0.0 1.5 1 0 0 1 1 1 1 Surp module TPR_19 PF14559.1 KUM59513.1 - 3.8e-07 30.3 1.9 0.016 15.5 0.2 3.4 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KUM59513.1 - 2.6e-06 27.9 0.0 0.067 13.8 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KUM59513.1 - 0.0005 19.9 0.5 0.091 12.7 0.1 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KUM59513.1 - 0.0041 16.9 0.1 2.6 8.1 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KUM59513.1 - 0.0062 17.0 3.1 22 6.0 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 KUM59513.1 - 0.016 14.8 0.0 0.19 11.3 0.0 2.6 2 1 0 2 2 2 0 TPR repeat TPR_6 PF13174.1 KUM59513.1 - 0.075 13.5 0.2 89 3.8 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KUM59513.1 - 0.086 13.0 0.6 5.7 7.3 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 KUM59513.1 - 0.13 12.7 5.5 37 5.1 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 KUM59513.1 - 0.18 11.8 2.9 0.66 9.9 0.2 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat SAC3_GANP PF03399.11 KUM59514.1 - 6.4e-09 35.6 0.0 9.7e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KUM59514.1 - 0.0026 17.5 0.1 0.0044 16.8 0.1 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 AKAP_110 PF05716.8 KUM59514.1 - 0.01 13.8 0.0 0.014 13.4 0.0 1.2 1 0 0 1 1 1 0 A-kinase anchor protein 110 kDa (AKAP 110) HlyIII PF03006.15 KUM59515.1 - 1.6e-54 184.7 11.9 1.7e-54 184.5 8.2 1.0 1 0 0 1 1 1 1 Haemolysin-III related Zn_clus PF00172.13 KUM59516.1 - 8.2e-08 32.0 8.0 8.2e-08 32.0 5.5 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 KUM59518.1 - 0.43 10.5 7.0 36 4.4 1.0 4.7 5 0 0 5 5 5 0 WD domain, G-beta repeat DUF1749 PF08538.5 KUM59519.1 - 3.5e-104 347.9 0.0 4.1e-104 347.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 KUM59519.1 - 1.4e-06 28.3 0.0 5.4e-06 26.4 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM59519.1 - 0.00031 20.4 0.0 0.00099 18.8 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF2305 PF10230.4 KUM59519.1 - 0.019 14.3 0.0 5.3 6.3 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2305) DUF900 PF05990.7 KUM59519.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Glycos_transf_2 PF00535.21 KUM59520.1 - 9.3e-36 123.0 0.0 1.1e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KUM59520.1 - 7.6e-14 52.0 0.0 1.1e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KUM59520.1 - 9.5e-12 44.5 0.0 1.8e-11 43.6 0.0 1.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KUM59520.1 - 0.0001 21.6 0.0 0.00018 20.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 KUM59520.1 - 0.0034 17.1 0.0 0.0046 16.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.1 KUM59520.1 - 0.037 14.3 0.0 0.068 13.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 FCH PF00611.18 KUM59521.1 - 4.8e-19 68.3 0.1 2.1e-18 66.3 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 KUM59521.1 - 4.8e-12 45.0 0.0 8.6e-12 44.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KUM59521.1 - 1.3e-10 40.6 0.0 5.5e-10 38.5 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 KUM59521.1 - 4e-10 39.1 0.0 9.6e-10 37.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Streptin-Immun PF11083.3 KUM59521.1 - 0.32 10.9 1.6 2.4 8.1 0.1 2.2 1 1 0 2 2 2 0 Lantibiotic streptin immunity protein TMA7 PF09072.5 KUM59522.1 - 7.4e-21 74.3 21.0 8.3e-21 74.2 14.6 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Pkinase PF00069.20 KUM59523.1 - 8.3e-53 179.1 0.0 1.3e-52 178.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM59523.1 - 1.9e-23 82.8 0.0 5.8e-23 81.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KUM59523.1 - 0.09 11.5 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Cyt-b5 PF00173.23 KUM59524.1 - 8e-13 48.0 0.0 1e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IncA PF04156.9 KUM59525.1 - 0.013 15.0 0.2 0.024 14.2 0.2 1.4 1 0 0 1 1 1 0 IncA protein Reo_sigmaC PF04582.7 KUM59525.1 - 0.054 12.6 0.0 0.095 11.8 0.0 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Ish1 PF10281.4 KUM59526.1 - 2.5e-74 244.9 19.4 5.3e-13 48.7 0.0 7.5 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein HeH PF12949.2 KUM59526.1 - 4.9e-12 45.1 0.1 0.033 13.7 0.1 5.9 6 0 0 6 6 6 3 HeH/LEM domain SAP PF02037.22 KUM59526.1 - 2.4e-10 39.6 0.0 1.1 8.9 0.0 6.6 6 2 0 6 6 6 3 SAP domain APC2 PF08672.6 KUM59526.1 - 7.6e-06 26.0 5.1 4.3 7.6 0.0 6.6 7 0 0 7 7 7 1 Anaphase promoting complex (APC) subunit 2 LEM PF03020.10 KUM59526.1 - 0.00091 18.6 0.0 21 4.6 0.0 4.8 5 0 0 5 5 5 0 LEM domain Slx4 PF09494.5 KUM59526.1 - 0.001 18.8 5.0 17 5.2 0.7 5.5 6 0 0 6 6 6 0 Slx4 endonuclease Amidase02_C PF12123.3 KUM59526.1 - 0.0094 15.5 0.2 0.56 9.8 0.2 3.6 4 0 0 4 4 4 1 N-acetylmuramoyl-l-alanine amidase Thymopoietin PF08198.6 KUM59526.1 - 0.01 15.3 0.1 0.18 11.3 0.0 2.7 3 0 0 3 3 3 0 Thymopoietin protein SAM_2 PF07647.12 KUM59526.1 - 0.27 11.1 5.3 13 5.7 0.1 4.9 6 0 0 6 6 6 0 SAM domain (Sterile alpha motif) Apolipoprotein PF01442.13 KUM59526.1 - 1.3 8.5 6.3 3.8 6.9 1.9 2.9 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain NTF2 PF02136.15 KUM59528.1 - 2.4e-23 82.7 0.2 2.8e-23 82.5 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain PQ-loop PF04193.9 KUM59529.1 - 3.4e-20 71.3 10.7 5.2e-12 45.1 1.9 3.8 4 1 1 5 5 5 2 PQ loop repeat DUF2644 PF10841.3 KUM59529.1 - 1.8 8.6 5.0 18 5.4 0.2 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2644) Pkinase PF00069.20 KUM59530.1 - 2e-60 204.1 0.0 2.7e-60 203.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM59530.1 - 4.8e-34 117.6 0.0 5.8e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM59530.1 - 2.7e-06 26.5 0.0 0.00042 19.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KUM59530.1 - 0.00089 19.0 0.0 0.0049 16.6 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KUM59530.1 - 0.11 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KUM59530.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase adh_short PF00106.20 KUM59531.1 - 1.9e-32 112.4 4.1 2.6e-32 112.0 2.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM59531.1 - 4.5e-25 88.8 0.7 4e-24 85.7 0.5 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM59531.1 - 7.5e-18 64.8 1.0 9.9e-18 64.4 0.7 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KUM59531.1 - 0.00092 18.9 1.5 0.0016 18.0 1.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KUM59531.1 - 0.0099 14.8 0.1 0.014 14.2 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein AdoHcyase_NAD PF00670.16 KUM59531.1 - 0.015 15.1 0.5 0.026 14.3 0.4 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Epimerase PF01370.16 KUM59531.1 - 0.018 14.5 0.4 0.025 14.0 0.3 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1188 PF06690.6 KUM59531.1 - 0.062 12.4 0.2 0.09 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Methyltransf_26 PF13659.1 KUM59531.1 - 0.073 13.1 0.1 0.14 12.2 0.1 1.4 1 1 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 KUM59531.1 - 0.078 12.1 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KUM59531.1 - 0.087 12.2 0.3 0.14 11.5 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Suf PF05843.9 KUM59532.1 - 1e-86 291.2 0.1 1e-86 291.2 0.0 3.9 5 2 1 6 6 6 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 KUM59532.1 - 0.0023 18.3 0.3 0.53 11.0 0.1 4.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KUM59532.1 - 0.0039 17.8 6.1 0.042 14.5 0.2 4.4 4 1 2 6 6 6 1 Tetratricopeptide repeat HAT PF02184.11 KUM59532.1 - 0.058 13.1 0.0 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat ASF1_hist_chap PF04729.8 KUM59533.1 - 1.9e-65 219.2 0.0 2.6e-65 218.7 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.7 KUM59533.1 - 0.046 11.6 25.1 0.061 11.2 17.4 1.1 1 0 0 1 1 1 0 Nop14-like family CHORD PF04968.7 KUM59535.1 - 0.014 15.5 1.3 0.014 15.5 0.9 2.3 2 1 1 3 3 3 0 CHORD Med26 PF08711.6 KUM59535.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 TFIIS helical bundle-like domain THUMP PF02926.12 KUM59536.1 - 6.1e-11 42.3 0.0 1e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 THUMP domain TPP_enzyme_N PF02776.13 KUM59537.1 - 1.2e-34 119.2 0.0 1.8e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KUM59537.1 - 2.7e-28 98.4 0.0 5.3e-28 97.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KUM59537.1 - 1.7e-14 53.6 0.0 4.5e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 KUM59537.1 - 0.02 13.6 0.0 0.034 12.8 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component OCC1 PF15506.1 KUM59537.1 - 0.48 10.3 2.7 6.1 6.8 0.2 3.1 3 0 0 3 3 3 0 OCC1 family Lgl_C PF08596.5 KUM59538.1 - 7.5e-132 439.5 0.0 4.7e-131 436.8 0.0 2.1 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 KUM59538.1 - 4.2e-06 26.4 2.7 0.17 11.7 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat Nup160 PF11715.3 KUM59538.1 - 0.025 12.7 0.0 0.14 10.2 0.0 2.1 3 0 0 3 3 3 0 Nucleoporin Nup120/160 APH PF01636.18 KUM59539.1 - 2e-08 34.2 0.1 3.4e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Piwi PF02171.12 KUM59540.1 - 3.6e-57 193.6 0.0 6.3e-57 192.8 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KUM59540.1 - 1.7e-14 53.3 0.4 3.4e-14 52.3 0.3 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 KUM59540.1 - 4.4e-10 38.7 0.0 9.6e-10 37.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PUF PF00806.14 KUM59541.1 - 8.4e-16 56.4 0.0 0.21 11.1 0.0 8.0 8 0 0 8 8 8 5 Pumilio-family RNA binding repeat Sec34 PF04136.10 KUM59543.1 - 2.7e-29 101.8 1.4 6.3e-29 100.7 1.0 1.6 1 0 0 1 1 1 1 Sec34-like family Exo70 PF03081.10 KUM59543.1 - 0.0054 15.5 3.9 0.97 8.1 0.1 3.3 4 0 0 4 4 4 2 Exo70 exocyst complex subunit TACC PF05010.9 KUM59543.1 - 0.035 13.8 0.5 0.16 11.7 0.2 2.1 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) DUF2127 PF09900.4 KUM59543.1 - 0.17 11.9 0.0 12 5.9 0.0 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2127) RCC1 PF00415.13 KUM59544.1 - 1.3e-31 108.5 0.6 3.9e-05 23.7 0.0 7.0 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KUM59544.1 - 3.8e-19 67.7 11.2 5.8e-11 41.7 0.0 6.5 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Abhydrolase_6 PF12697.2 KUM59545.1 - 5.2e-26 91.9 0.2 6.9e-26 91.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM59545.1 - 2.1e-12 47.0 0.2 2e-11 43.8 0.1 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KUM59545.1 - 1.6e-10 40.8 0.0 1.6e-09 37.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KUM59545.1 - 6e-05 22.8 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Pyridoxal_deC PF00282.14 KUM59546.1 - 1.1e-80 270.8 0.0 2.7e-80 269.6 0.0 1.6 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KUM59546.1 - 6.5e-05 22.2 0.0 9e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KUM59546.1 - 0.00026 19.8 0.0 0.00039 19.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Collagen PF01391.13 KUM59546.1 - 0.0023 17.4 5.9 0.005 16.3 4.1 1.5 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) MFS_1 PF07690.11 KUM59547.1 - 0.0012 17.5 1.7 0.0012 17.5 1.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily BT1 PF03092.11 KUM59547.1 - 0.034 12.8 0.7 0.045 12.4 0.5 1.1 1 0 0 1 1 1 0 BT1 family Pkinase PF00069.20 KUM59548.1 - 2.6e-62 210.3 0.0 6e-62 209.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM59548.1 - 3.4e-43 147.6 0.0 5e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM59548.1 - 7.8e-08 31.6 0.0 2.7e-07 29.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KUM59548.1 - 0.017 14.2 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SIR2 PF02146.12 KUM59549.1 - 3.4e-58 196.2 0.0 4.8e-58 195.7 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Zn-ribbon_8 PF09723.5 KUM59549.1 - 0.19 11.7 2.9 0.42 10.5 2.0 1.5 1 0 0 1 1 1 0 Zinc ribbon domain COG4 PF08318.7 KUM59550.1 - 1.7e-107 359.0 0.0 2.4e-107 358.5 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein TMF_TATA_bd PF12325.3 KUM59550.1 - 0.37 10.5 2.1 5.5 6.7 0.1 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Cu-oxidase_3 PF07732.10 KUM59551.1 - 5.5e-39 132.5 3.2 5.5e-39 132.5 2.2 2.5 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KUM59551.1 - 1.2e-36 125.2 1.0 1.2e-36 125.2 0.7 3.3 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 KUM59551.1 - 3.8e-36 124.3 0.7 1.1e-33 116.3 0.2 2.7 2 0 0 2 2 2 2 Multicopper oxidase Cupin_8 PF13621.1 KUM59552.1 - 1.8e-09 37.4 0.0 3.5e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain PHD PF00628.24 KUM59552.1 - 2.6e-09 36.6 6.0 2.6e-09 36.6 4.2 2.7 3 0 0 3 3 3 1 PHD-finger JmjC PF02373.17 KUM59552.1 - 5.9e-09 36.1 0.1 5.1e-08 33.1 0.1 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD_2 PF13831.1 KUM59552.1 - 0.0021 17.3 5.0 0.0021 17.3 2.0 2.2 2 0 0 2 2 2 1 PHD-finger DUF3294 PF07957.6 KUM59552.1 - 0.095 12.2 0.1 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) Dickkopf_N PF04706.7 KUM59552.1 - 5.2 7.3 14.8 3.9 7.7 1.8 3.2 3 0 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region RRM_1 PF00076.17 KUM59553.1 - 2.5e-18 65.4 0.2 4.2e-18 64.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM59553.1 - 1.8e-13 50.2 0.0 3e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM59553.1 - 5.9e-09 35.6 0.1 9.4e-09 34.9 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DPCD PF14913.1 KUM59553.1 - 0.075 12.1 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 DPCD protein family APH PF01636.18 KUM59555.1 - 1.5e-25 90.3 0.0 1.9e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KUM59555.1 - 1.1e-05 25.1 0.0 2.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Hexokinase_2 PF03727.11 KUM59556.1 - 4.9e-85 284.6 0.0 6.6e-85 284.1 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KUM59556.1 - 2.1e-74 249.3 0.0 2.8e-74 248.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase DUF3661 PF12400.3 KUM59557.1 - 7.3e-43 145.7 4.9 1.2e-42 145.0 3.4 1.3 1 0 0 1 1 1 1 Vaculolar membrane protein Zn_clus PF00172.13 KUM59558.1 - 0.0062 16.4 9.2 0.014 15.3 6.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 KUM59558.1 - 0.18 11.6 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 PAS fold Flavokinase PF01687.12 KUM59559.1 - 1.5e-34 118.5 0.0 1.9e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase MFS_1 PF07690.11 KUM59560.1 - 5.1e-40 137.2 30.5 5.1e-40 137.2 21.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KUM59560.1 - 4.6e-07 28.4 1.1 4.6e-07 28.4 0.8 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 KUM59560.1 - 0.00064 17.9 3.9 0.00093 17.4 2.7 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector Bap31 PF05529.7 KUM59560.1 - 0.0024 17.3 0.1 0.0084 15.5 0.1 1.8 2 0 0 2 2 2 1 B-cell receptor-associated protein 31-like E1-E2_ATPase PF00122.15 KUM59560.1 - 0.48 9.4 0.0 0.48 9.4 0.0 1.9 3 0 0 3 3 3 0 E1-E2 ATPase E1-E2_ATPase PF00122.15 KUM59562.1 - 9.9e-83 276.6 0.2 1.6e-82 275.9 0.1 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KUM59562.1 - 1.8e-43 148.2 3.3 3.1e-43 147.4 0.1 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KUM59562.1 - 1.1e-28 101.1 0.0 4.4e-28 99.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KUM59562.1 - 2.9e-20 71.4 0.0 5.7e-20 70.5 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KUM59562.1 - 6.4e-14 52.5 0.0 1.8e-13 51.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KUM59562.1 - 8.8e-14 51.2 0.0 1.8e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KUM59562.1 - 7.3e-05 22.4 1.3 0.0003 20.4 0.8 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.8 KUM59563.1 - 1.4e-38 131.2 0.0 2.6e-38 130.3 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KUM59563.1 - 4.3e-07 29.0 0.8 9.3e-07 27.9 0.2 1.8 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 KUM59563.1 - 0.09 12.3 0.1 0.94 9.0 0.0 2.1 2 0 0 2 2 2 0 ScpA/B protein DUF3926 PF13080.1 KUM59563.1 - 0.13 11.7 0.0 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3926) Ammonium_transp PF00909.16 KUM59564.1 - 2.6e-114 381.8 28.6 3e-114 381.5 19.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family SnoaL PF07366.7 KUM59566.1 - 0.0016 18.0 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase RGS-like PF09128.6 KUM59566.1 - 0.66 9.4 1.5 1.3 8.4 1.0 1.4 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Cu-oxidase_2 PF07731.9 KUM59568.1 - 4.9e-29 100.6 1.8 5.6e-25 87.4 0.6 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KUM59568.1 - 5.1e-16 58.4 0.1 5.1e-15 55.2 0.0 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 KUM59568.1 - 2.5e-05 24.2 0.0 0.0047 16.8 0.0 2.9 3 0 0 3 3 3 2 Multicopper oxidase GFO_IDH_MocA PF01408.17 KUM59569.1 - 1.5e-19 70.6 0.1 3.6e-19 69.4 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold ubiquitin PF00240.18 KUM59570.1 - 6.8e-34 115.0 1.0 9.3e-34 114.6 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 KUM59570.1 - 8.8e-30 102.0 10.5 1.4e-29 101.3 7.3 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 KUM59570.1 - 2.1e-19 68.9 1.0 3.1e-19 68.4 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KUM59570.1 - 2.2e-05 24.5 0.2 7.5e-05 22.9 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KUM59570.1 - 0.00056 19.6 0.0 0.00078 19.1 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing DUF2407 PF10302.4 KUM59570.1 - 0.017 15.3 0.1 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 KUM59570.1 - 0.022 14.6 0.0 0.042 13.7 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Abhydrolase_6 PF12697.2 KUM59571.1 - 1.7e-24 86.9 3.7 1.7e-24 86.9 2.6 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM59571.1 - 3.8e-15 56.0 0.0 1.4e-13 50.9 0.0 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KUM59571.1 - 6e-12 45.5 0.0 3.8e-09 36.4 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family DUF915 PF06028.6 KUM59571.1 - 9.5e-05 21.5 0.0 0.00016 20.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 KUM59571.1 - 0.00016 21.1 0.0 0.00039 19.9 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.2 KUM59571.1 - 0.0057 15.5 0.0 0.0089 14.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_2 PF02230.11 KUM59571.1 - 0.0091 15.4 0.0 0.15 11.4 0.0 2.3 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 KUM59571.1 - 0.015 14.8 0.0 0.094 12.2 0.0 2.2 3 0 0 3 3 3 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 KUM59571.1 - 0.05 13.2 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.15 KUM59571.1 - 0.064 13.4 2.1 0.19 11.9 0.3 2.6 2 1 0 2 2 2 0 Thioesterase domain Chlorophyllase PF07224.6 KUM59571.1 - 0.093 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase RabGAP-TBC PF00566.13 KUM59572.1 - 2.5e-28 99.0 0.3 3.8e-28 98.4 0.2 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Yip1 PF04893.12 KUM59573.1 - 3.5e-15 55.9 15.4 4.6e-15 55.5 10.7 1.2 1 0 0 1 1 1 1 Yip1 domain CopD PF05425.8 KUM59573.1 - 0.045 13.9 7.5 1.5 9.0 1.0 2.3 2 0 0 2 2 2 0 Copper resistance protein D p450 PF00067.17 KUM59575.1 - 1.3e-53 182.1 0.0 1.8e-53 181.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Rhodanese PF00581.15 KUM59576.1 - 2.3e-10 40.7 0.0 4.9e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain GTP_EFTU PF00009.22 KUM59577.1 - 3e-32 111.5 0.0 3e-31 108.3 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KUM59577.1 - 4.8e-18 65.0 0.1 1.6e-17 63.3 0.1 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KUM59577.1 - 8.3e-12 45.0 0.7 7.7e-10 38.7 0.0 3.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KUM59577.1 - 1.6e-06 28.0 0.2 8.7e-06 25.6 0.0 2.4 3 0 0 3 3 3 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KUM59577.1 - 0.00059 19.4 0.0 0.0015 18.1 0.0 1.8 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Miro PF08477.8 KUM59577.1 - 0.0022 18.4 1.4 0.01 16.3 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU_D4 PF14578.1 KUM59577.1 - 0.024 14.2 0.1 0.092 12.3 0.1 2.0 1 1 0 1 1 1 0 Elongation factor Tu domain 4 AAA_22 PF13401.1 KUM59577.1 - 0.043 13.9 0.0 0.21 11.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain Mucin PF01456.12 KUM59577.1 - 1.2 8.8 6.5 0.18 11.5 0.8 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein Ribosomal_L34 PF00468.12 KUM59578.1 - 0.081 12.6 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L34 TatD_DNase PF01026.16 KUM59579.1 - 1.8e-36 125.6 0.0 3.4e-36 124.7 0.0 1.4 1 1 0 1 1 1 1 TatD related DNase RXT2_N PF08595.6 KUM59579.1 - 0.033 13.9 0.5 0.071 12.9 0.4 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal PPR_3 PF13812.1 KUM59582.1 - 4.6e-22 76.3 9.4 0.0005 20.1 0.4 11.0 11 1 1 12 12 12 5 Pentatricopeptide repeat domain PPR_2 PF13041.1 KUM59582.1 - 8.2e-21 73.7 0.1 1.6e-08 34.3 0.0 6.1 5 2 2 7 7 7 4 PPR repeat family PPR PF01535.15 KUM59582.1 - 5.5e-15 54.2 1.7 0.043 13.8 0.0 8.3 10 0 0 10 10 10 4 PPR repeat PPR_1 PF12854.2 KUM59582.1 - 1.7e-09 36.9 0.5 0.91 9.0 0.0 5.4 5 0 0 5 5 5 4 PPR repeat ATP13 PF12921.2 KUM59582.1 - 0.028 13.7 0.0 1.5 8.2 0.0 3.0 2 1 0 2 2 2 0 Mitochondrial ATPase expression DUF4081 PF13312.1 KUM59582.1 - 0.065 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4081) Glyco_trans_4_2 PF13477.1 KUM59582.1 - 0.2 11.5 0.0 0.69 9.7 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase 4-like MMS1_N PF10433.4 KUM59583.1 - 9.7e-128 426.4 0.0 3e-127 424.8 0.0 1.8 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 KUM59583.1 - 3e-09 36.4 0.0 4e-08 32.7 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region PQQ_3 PF13570.1 KUM59583.1 - 0.034 14.4 1.8 6 7.2 0.1 3.9 3 0 0 3 3 3 0 PQQ-like domain MCM PF00493.18 KUM59585.1 - 2.4e-128 427.6 0.1 3.4e-128 427.1 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KUM59585.1 - 2.5e-14 53.8 0.0 5.8e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KUM59585.1 - 3.6e-06 26.2 0.0 4.2e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KUM59585.1 - 0.0063 16.1 0.0 0.015 14.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TFIIF_alpha PF05793.7 KUM59585.1 - 2.8 6.2 11.7 4.1 5.6 8.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Spo7 PF03907.8 KUM59586.1 - 1.4e-64 217.5 0.0 1.8e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 Spo7-like protein RRN7 PF11781.3 KUM59587.1 - 1.8e-08 33.7 4.5 4e-08 32.6 3.1 1.5 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 Fungal_trans PF04082.13 KUM59589.1 - 2e-23 82.6 0.0 3.5e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM59589.1 - 4e-09 36.2 11.9 5.9e-09 35.6 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aa_trans PF01490.13 KUM59590.1 - 4.9e-42 143.8 32.0 5.8e-42 143.6 22.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KUM59590.1 - 0.0022 16.8 18.5 0.0045 15.8 12.8 1.6 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family CAAD PF14159.1 KUM59590.1 - 2.9 7.6 13.0 0.27 10.8 0.1 4.2 5 0 0 5 5 5 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Condensation PF00668.15 KUM59591.1 - 2.1e-22 79.3 0.0 4.1e-22 78.3 0.0 1.4 1 1 0 1 1 1 1 Condensation domain HxxPF_rpt PF13745.1 KUM59591.1 - 4.9e-07 29.9 0.0 1.3e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 HxxPF-repeated domain DUF1832 PF08870.6 KUM59591.1 - 0.032 13.9 0.0 0.075 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1832) AATase PF07247.7 KUM59591.1 - 0.053 12.0 0.0 0.084 11.4 0.0 1.3 1 0 0 1 1 1 0 Alcohol acetyltransferase AMP-binding PF00501.23 KUM59592.1 - 7.8e-78 261.7 0.0 9.5e-78 261.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KUM59592.1 - 0.00078 20.3 0.1 0.002 19.0 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BATS PF06968.8 KUM59594.1 - 3.3e-27 94.1 0.0 2.2e-26 91.5 0.0 2.3 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 KUM59594.1 - 3.2e-16 59.9 0.1 5.8e-16 59.1 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily AMP-binding PF00501.23 KUM59595.1 - 8.1e-78 261.6 0.0 1e-77 261.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KUM59595.1 - 3.1e-10 40.8 0.0 8.1e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FAD_binding_4 PF01565.18 KUM59597.1 - 1.4e-18 66.7 2.5 4.8e-18 64.9 1.7 2.0 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KUM59597.1 - 3.5e-12 46.0 0.8 9.6e-12 44.6 0.6 1.8 1 0 0 1 1 1 1 Berberine and berberine like Sugar_tr PF00083.19 KUM59598.1 - 8.7e-89 298.1 23.7 1.1e-88 297.8 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM59598.1 - 1.3e-33 116.1 46.2 9e-29 100.2 17.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KUM59598.1 - 1.4e-05 23.5 0.7 2.7e-05 22.5 0.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Transferase PF02458.10 KUM59602.1 - 1.6e-24 86.1 0.0 2.4e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Transferase family Condensation PF00668.15 KUM59602.1 - 0.066 12.0 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Condensation domain Citrate_synt PF00285.16 KUM59603.1 - 2.3e-98 329.2 0.0 2.7e-98 328.9 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Wyosine_form PF08608.7 KUM59603.1 - 0.094 12.8 0.0 14 5.8 0.0 2.5 2 0 0 2 2 2 0 Wyosine base formation ABC_tran PF00005.22 KUM59604.1 - 1.5e-47 161.3 0.0 6.7e-26 91.2 0.0 3.7 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KUM59604.1 - 3.8e-15 56.6 5.7 0.00049 20.1 0.0 4.5 3 2 1 4 4 3 3 AAA domain SMC_N PF02463.14 KUM59604.1 - 4.5e-11 42.3 0.2 0.0028 16.9 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KUM59604.1 - 1.5e-06 27.6 1.3 0.047 13.2 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 KUM59604.1 - 3.7e-06 27.4 0.0 0.011 16.2 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein SbcCD_C PF13558.1 KUM59604.1 - 4.8e-06 26.3 0.0 0.098 12.5 0.0 3.1 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 KUM59604.1 - 5.8e-06 26.7 0.2 0.056 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KUM59604.1 - 7.6e-06 25.2 0.0 0.49 9.3 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.18 KUM59604.1 - 1.9e-05 24.5 0.0 0.2 11.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 KUM59604.1 - 2.7e-05 23.3 0.0 0.21 10.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KUM59604.1 - 3.3e-05 24.0 0.0 0.021 14.9 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KUM59604.1 - 4.1e-05 24.3 0.0 0.65 10.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain Chromo PF00385.19 KUM59604.1 - 8.5e-05 22.1 0.1 0.00017 21.1 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain NACHT PF05729.7 KUM59604.1 - 0.00014 21.5 0.1 0.034 13.7 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.1 KUM59604.1 - 0.00016 21.6 0.0 0.2 11.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 KUM59604.1 - 0.0003 20.5 0.0 1.1 8.9 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 KUM59604.1 - 0.00031 20.6 1.4 0.26 11.0 0.3 3.2 3 0 0 3 3 2 1 Domain of unknown function DUF87 AAA_10 PF12846.2 KUM59604.1 - 0.0004 19.9 1.7 1.1 8.6 0.0 3.5 4 0 0 4 4 4 2 AAA-like domain Dynamin_N PF00350.18 KUM59604.1 - 0.00043 20.1 0.0 0.21 11.3 0.0 3.4 3 0 0 3 3 3 1 Dynamin family ArgK PF03308.11 KUM59604.1 - 0.0027 16.5 0.8 0.81 8.4 0.1 2.4 2 0 0 2 2 2 1 ArgK protein RNA_helicase PF00910.17 KUM59604.1 - 0.0042 17.2 0.1 1 9.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 KUM59604.1 - 0.0047 16.7 0.0 1.7 8.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KUM59604.1 - 0.011 15.2 0.1 1.3 8.4 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family HEAT_2 PF13646.1 KUM59604.1 - 0.014 15.7 2.9 5.3 7.4 0.0 3.7 3 1 1 4 4 4 0 HEAT repeats AAA_13 PF13166.1 KUM59604.1 - 0.016 13.7 0.1 1.6 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KUM59604.1 - 0.017 15.3 0.0 0.73 10.0 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DNA_ligase_OB_2 PF14743.1 KUM59604.1 - 0.017 14.7 0.3 0.037 13.7 0.2 1.6 1 0 0 1 1 1 0 DNA ligase OB-like domain DUF815 PF05673.8 KUM59604.1 - 0.022 13.6 0.0 2.7 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.4 KUM59604.1 - 0.03 13.7 0.0 9.6 5.6 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ipi1_N PF12333.3 KUM59604.1 - 0.035 14.0 0.0 13 5.8 0.0 3.2 3 0 0 3 3 2 0 Rix1 complex component involved in 60S ribosome maturation AAA_30 PF13604.1 KUM59604.1 - 0.037 13.6 0.2 15 5.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.1 KUM59604.1 - 0.037 14.3 0.0 12 6.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KUM59604.1 - 0.038 13.3 0.0 7.5 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain CLASP_N PF12348.3 KUM59604.1 - 0.085 12.2 0.0 2.1 7.6 0.2 2.3 2 0 0 2 2 2 0 CLASP N terminal Septin PF00735.13 KUM59604.1 - 0.094 11.7 0.0 13 4.7 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_14 PF13173.1 KUM59604.1 - 0.16 11.9 0.0 7.8 6.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.3 KUM59604.1 - 0.86 6.8 1.3 2.7 5.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) HEAT_EZ PF13513.1 KUM59604.1 - 1.6 9.3 4.9 1.1e+02 3.5 0.0 4.5 4 0 0 4 4 4 0 HEAT-like repeat AAA_22 PF13401.1 KUM59605.1 - 0.00041 20.4 2.3 0.0026 17.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KUM59605.1 - 0.00043 20.3 0.1 0.0019 18.2 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain TPR_19 PF14559.1 KUM59605.1 - 0.00047 20.4 3.0 1.1 9.5 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 KUM59605.1 - 0.003 17.9 3.7 8.9 7.0 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KUM59605.1 - 0.0033 17.9 6.3 0.21 12.3 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat NACHT PF05729.7 KUM59605.1 - 0.064 12.9 0.2 0.34 10.5 0.1 2.2 1 1 0 1 1 1 0 NACHT domain TPR_16 PF13432.1 KUM59605.1 - 0.15 12.7 4.0 30 5.4 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KUM59605.1 - 2.8 7.6 17.1 0.023 14.3 1.9 3.7 4 0 0 4 4 4 0 TPR repeat FA_hydroxylase PF04116.8 KUM59606.1 - 5.9e-14 52.4 16.3 5.9e-14 52.4 11.3 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily AAA_13 PF13166.1 KUM59609.1 - 0.0012 17.3 0.8 0.0021 16.6 0.6 1.3 1 0 0 1 1 1 1 AAA domain Spc7 PF08317.6 KUM59609.1 - 0.0018 16.9 2.1 0.0037 15.9 1.4 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF2353 PF09789.4 KUM59609.1 - 0.0026 17.0 11.8 0.051 12.8 2.6 2.3 1 1 1 2 2 2 2 Uncharacterized coiled-coil protein (DUF2353) TMF_TATA_bd PF12325.3 KUM59609.1 - 0.0067 16.1 1.6 2.2 8.0 0.9 2.4 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding Reo_sigmaC PF04582.7 KUM59609.1 - 0.011 14.9 0.0 0.023 13.9 0.0 1.5 1 0 0 1 1 1 0 Reovirus sigma C capsid protein V-SNARE PF05008.10 KUM59609.1 - 0.013 15.6 2.2 0.013 15.6 1.5 2.1 2 0 0 2 2 1 0 Vesicle transport v-SNARE protein N-terminus TPR_MLP1_2 PF07926.7 KUM59609.1 - 0.032 13.9 6.4 0.64 9.7 1.5 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF948 PF06103.6 KUM59609.1 - 0.06 13.2 1.3 0.74 9.7 0.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.7 KUM59609.1 - 0.073 12.8 0.2 0.073 12.8 0.1 2.4 3 0 0 3 3 3 0 Laminin Domain II Rop-like PF05082.8 KUM59609.1 - 0.11 11.9 0.6 0.31 10.5 0.4 1.7 1 0 0 1 1 1 0 Rop-like NPV_P10 PF05531.7 KUM59609.1 - 0.15 12.3 10.7 0.5 10.6 0.4 3.1 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.14 KUM59609.1 - 0.27 9.0 6.0 0.35 8.6 4.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Syntaxin-6_N PF09177.6 KUM59609.1 - 0.28 11.6 3.9 0.68 10.3 1.3 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4407 PF14362.1 KUM59609.1 - 0.28 10.0 3.5 0.45 9.4 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SNARE PF05739.14 KUM59609.1 - 0.36 10.5 9.3 0.035 13.7 2.3 2.3 2 0 0 2 2 2 0 SNARE domain ISG65-75 PF11727.3 KUM59609.1 - 0.6 9.1 4.5 1.3 7.9 3.1 1.5 1 0 0 1 1 1 0 Invariant surface glycoprotein Phage_GP20 PF06810.6 KUM59609.1 - 0.6 9.5 11.1 0.31 10.4 4.0 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 TMPIT PF07851.8 KUM59609.1 - 0.95 8.4 6.8 0.096 11.7 1.6 1.5 2 0 0 2 2 2 0 TMPIT-like protein Atg14 PF10186.4 KUM59609.1 - 1 8.2 7.7 0.34 9.8 3.0 1.8 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 KUM59609.1 - 1.8 8.1 9.3 3.9 7.0 4.9 2.3 1 1 1 2 2 2 0 IncA protein Fib_alpha PF08702.5 KUM59609.1 - 2 8.5 12.4 0.63 10.1 3.0 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF2203 PF09969.4 KUM59609.1 - 2.2 8.4 4.2 8.9 6.5 1.3 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF1664 PF07889.7 KUM59609.1 - 2.5 7.9 10.2 8.3 6.2 4.7 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Med9 PF07544.8 KUM59609.1 - 5.1 6.9 8.0 1.9 8.2 0.6 2.8 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 YtxH PF12732.2 KUM59609.1 - 7.8 6.9 9.0 1.8 8.9 1.8 2.8 2 1 1 3 3 3 0 YtxH-like protein NOC3p PF07540.6 KUM59610.1 - 7.1e-33 112.7 0.4 7.1e-33 112.7 0.3 2.3 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.12 KUM59610.1 - 4.4e-32 110.7 1.0 1.2e-31 109.3 0.0 2.2 2 0 0 2 2 2 1 CBF/Mak21 family DUF1349 PF07081.6 KUM59612.1 - 2.8e-18 65.9 0.0 2.6e-17 62.7 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) ATP-synt_C PF00137.16 KUM59613.1 - 1.3e-14 53.7 10.6 2.2e-14 53.0 7.4 1.4 1 0 0 1 1 1 1 ATP synthase subunit C Sulfate_transp PF00916.15 KUM59614.1 - 2e-47 161.5 7.4 2.3e-27 95.7 0.7 2.6 1 1 1 2 2 2 2 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KUM59614.1 - 9.3e-32 108.5 3.3 9.3e-32 108.5 2.3 2.7 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KUM59614.1 - 4.5e-09 35.7 0.0 9.1e-09 34.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain SNN_transmemb PF09049.5 KUM59614.1 - 0.02 14.5 4.3 0.027 14.1 1.2 2.7 2 0 0 2 2 2 0 Stannin transmembrane UPF0113 PF03657.8 KUM59615.1 - 8.8e-07 28.7 0.0 9.8e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 KUM59615.1 - 1.8e-06 27.5 0.0 2.4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 PUA domain Cullin_binding PF03556.10 KUM59616.1 - 5.4e-32 110.3 1.1 6.1e-32 110.2 0.8 1.0 1 0 0 1 1 1 1 Cullin binding Cript PF10235.4 KUM59617.1 - 2.6e-34 117.4 7.8 2.6e-34 117.4 5.4 1.6 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.2 KUM59617.1 - 0.0082 15.9 14.8 0.046 13.5 6.3 2.6 1 1 1 2 2 2 2 Double zinc ribbon AAA_29 PF13555.1 KUM59617.1 - 0.032 13.7 1.5 4.9 6.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain zf-ribbon_3 PF13248.1 KUM59617.1 - 0.11 11.6 11.2 1.4 8.1 2.2 3.3 2 1 1 3 3 3 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 KUM59617.1 - 0.18 11.3 12.8 16 5.1 0.1 3.4 2 1 0 2 2 2 0 zinc-ribbon domain ABC_tran PF00005.22 KUM59617.1 - 0.21 11.8 3.3 2 8.7 0.6 2.2 1 1 1 2 2 2 0 ABC transporter zf-BED PF02892.10 KUM59617.1 - 0.4 10.4 5.6 3.5 7.4 1.3 2.5 2 0 0 2 2 2 0 BED zinc finger DUF581 PF04570.9 KUM59617.1 - 4.2 6.7 12.6 3.4 7.0 1.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF581) NinF PF05810.7 KUM59617.1 - 4.4 7.1 8.4 12 5.8 0.0 2.8 2 1 1 3 3 3 0 NinF protein DUF2039 PF10217.4 KUM59617.1 - 9.5 6.3 19.2 5 7.2 8.5 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Prim_Zn_Ribbon PF08273.7 KUM59617.1 - 9.6 6.3 11.2 32 4.7 0.0 3.9 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase MRP-L46 PF11788.3 KUM59618.1 - 2.7e-35 121.3 1.0 5.8e-35 120.3 0.7 1.6 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 KUM59618.1 - 5.3e-05 22.8 0.0 0.00011 21.9 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 KUM59618.1 - 0.086 12.2 0.1 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 NUDIX domain CAF1 PF04857.15 KUM59619.1 - 2.7e-44 151.4 0.0 3.5e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease DUF572 PF04502.8 KUM59620.1 - 0.021 14.0 10.0 0.037 13.2 6.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) adh_short PF00106.20 KUM59621.1 - 1.4e-29 103.1 0.4 1.9e-29 102.7 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM59621.1 - 3.8e-18 66.1 0.3 5e-18 65.7 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM59621.1 - 4.8e-13 49.1 0.3 6.5e-13 48.7 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KUM59621.1 - 3.3e-07 30.4 0.1 1.2e-06 28.6 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KUM59621.1 - 9.4e-05 21.4 0.2 0.00015 20.7 0.1 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KUM59621.1 - 0.00012 21.6 1.1 0.0007 19.1 0.9 2.0 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KUM59621.1 - 0.00054 19.6 0.4 0.0012 18.5 0.3 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Saccharop_dh PF03435.13 KUM59621.1 - 0.0037 16.2 0.1 0.0053 15.7 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KUM59621.1 - 0.0037 17.3 0.2 0.011 15.7 0.1 2.1 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 KUM59621.1 - 0.073 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_tran_WecB PF03808.8 KUM59621.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family DUF972 PF06156.8 KUM59622.1 - 0.017 15.4 4.3 0.82 10.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF4137 PF13593.1 KUM59623.1 - 1.8e-89 299.9 19.0 2.1e-89 299.7 13.2 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 KUM59623.1 - 3e-08 33.2 7.7 3e-08 33.2 5.3 2.0 2 1 0 2 2 2 1 Sodium Bile acid symporter family LrgA PF03788.9 KUM59623.1 - 0.022 14.4 1.4 0.022 14.4 1.0 2.9 2 1 0 2 2 2 0 LrgA family PalH PF08733.5 KUM59623.1 - 0.5 9.1 10.3 2.4 6.9 0.2 3.0 3 0 0 3 3 3 0 PalH/RIM21 Mito_carr PF00153.22 KUM59624.1 - 3.7e-67 222.0 4.4 1.4e-22 79.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Mpv17_PMP22 PF04117.7 KUM59626.1 - 5.4e-14 51.5 0.5 4.9e-12 45.3 0.3 2.3 2 0 0 2 2 2 2 Mpv17 / PMP22 family Dynamin_N PF00350.18 KUM59629.1 - 3.9e-26 91.8 0.1 2.7e-23 82.6 0.0 3.0 2 1 0 2 2 2 2 Dynamin family Dynamin_M PF01031.15 KUM59629.1 - 1.9e-15 56.4 0.5 2.9e-13 49.2 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 KUM59629.1 - 6.6e-05 22.8 0.1 0.0088 15.9 0.0 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase GED PF02212.13 KUM59629.1 - 0.0013 18.5 0.1 0.0039 17.0 0.0 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain Miro PF08477.8 KUM59629.1 - 0.0039 17.6 0.0 0.01 16.3 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein IIGP PF05049.8 KUM59629.1 - 0.026 13.3 0.1 4.4 6.0 0.0 2.6 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) NAAA-beta PF15508.1 KUM59629.1 - 0.13 12.6 2.0 4 7.8 0.0 3.8 5 0 0 5 5 5 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase MobB PF03205.9 KUM59629.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B tRNA-synt_2 PF00152.15 KUM59630.1 - 1.6e-70 237.5 0.9 1.9e-43 148.5 0.0 2.2 1 1 1 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KUM59630.1 - 4.6e-12 45.6 0.1 1.4e-11 44.0 0.0 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain ChAPs PF09295.5 KUM59630.1 - 0.057 12.1 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) POX PF07526.6 KUM59630.1 - 4.4 7.5 7.4 1.8 8.7 3.1 1.8 2 0 0 2 2 2 0 Associated with HOX zf-B_box PF00643.19 KUM59631.1 - 0.097 12.5 5.2 0.16 11.9 3.6 1.2 1 0 0 1 1 1 0 B-box zinc finger zf-C3HC4_2 PF13923.1 KUM59631.1 - 0.14 12.1 4.1 0.24 11.4 2.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KUM59631.1 - 0.16 11.5 4.7 0.29 10.7 3.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain COX15-CtaA PF02628.10 KUM59632.1 - 2.2e-96 322.2 6.3 2.7e-96 322.0 4.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein zf-C3HC PF07967.8 KUM59633.1 - 6.8e-40 135.9 0.3 1.5e-36 125.0 0.1 2.3 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 KUM59633.1 - 8.3e-35 118.5 0.3 5.6e-32 109.4 0.0 2.7 2 0 0 2 2 2 2 Rsm1-like Abhydrolase_3 PF07859.8 KUM59637.1 - 5e-39 134.0 0.0 6.7e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KUM59637.1 - 6.2e-11 41.7 0.0 1.2e-10 40.7 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 KUM59637.1 - 0.00041 19.0 0.0 0.00057 18.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KUM59637.1 - 0.002 17.8 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KUM59637.1 - 0.11 11.6 0.0 0.24 10.5 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2974 PF11187.3 KUM59637.1 - 0.17 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PEPCK_ATP PF01293.15 KUM59638.1 - 2.3e-214 712.2 0.0 2.7e-214 711.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 KUM59638.1 - 0.079 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KUM59638.1 - 0.16 11.9 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain MFS_1 PF07690.11 KUM59640.1 - 2.4e-12 46.2 24.9 5.7e-12 45.0 17.2 1.6 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KUM59640.1 - 1.5e-07 31.0 5.5 1.5e-07 31.0 3.8 2.5 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 Mito_carr PF00153.22 KUM59641.1 - 1.7e-57 191.1 3.2 5e-20 71.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-Nse PF11789.3 KUM59642.1 - 2.5e-22 78.1 1.4 5.1e-22 77.1 1.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 KUM59642.1 - 5.6e-05 22.8 0.3 9.2e-05 22.1 0.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 KUM59642.1 - 0.005 16.5 0.7 0.016 14.9 0.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 KUM59642.1 - 0.064 12.7 3.8 0.29 10.6 2.7 1.9 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger Pox_MCEL PF03291.11 KUM59643.1 - 1.6e-63 214.6 0.0 2.5e-31 108.8 0.0 3.8 3 1 0 3 3 3 3 mRNA capping enzyme Methyltransf_12 PF08242.7 KUM59643.1 - 1.9e-07 31.4 0.0 1.2e-06 28.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM59643.1 - 6.6e-07 29.7 0.1 0.025 15.0 0.0 2.7 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.1 KUM59643.1 - 1.7e-05 24.4 0.0 0.0036 16.9 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 KUM59643.1 - 2.4e-05 24.1 0.0 4.1e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM59643.1 - 4.7e-05 23.9 0.0 0.00011 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM59643.1 - 0.00026 21.3 0.0 0.0012 19.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KUM59643.1 - 0.0083 15.1 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family YqzH PF14164.1 KUM59644.1 - 1.7 8.6 3.6 34 4.4 0.5 2.4 2 0 0 2 2 2 0 YqzH-like protein DUF1765 PF08578.5 KUM59646.1 - 9.6e-46 154.9 5.2 9.6e-46 154.9 3.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) TPP_enzyme_N PF02776.13 KUM59647.1 - 1.6e-36 125.3 0.1 2.6e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KUM59647.1 - 3.6e-18 65.6 0.0 8.6e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KUM59647.1 - 3.1e-15 56.0 0.2 1e-13 51.1 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DIL PF01843.14 KUM59649.1 - 2.9e-17 62.4 3.4 1.9e-15 56.6 2.4 2.6 1 1 0 1 1 1 1 DIL domain Ank_2 PF12796.2 KUM59649.1 - 9.4e-17 61.1 0.0 4.6e-16 58.9 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KUM59649.1 - 6e-13 48.5 0.0 2.3e-05 24.4 0.0 3.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KUM59649.1 - 8.4e-13 47.4 0.0 4e-05 23.1 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KUM59649.1 - 1.3e-07 31.9 0.0 0.012 16.1 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM59649.1 - 4.8e-07 29.3 0.2 0.005 16.9 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat TFIIB PF00382.14 KUM59650.1 - 9.8e-40 134.2 0.2 6.3e-20 70.7 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 KUM59650.1 - 1.9e-10 39.8 1.1 1.9e-10 39.8 0.7 1.7 2 0 0 2 2 2 1 TFIIB zinc-binding Cyclin_N PF00134.18 KUM59650.1 - 0.00075 19.0 0.1 0.55 9.8 0.0 2.3 1 1 0 2 2 2 2 Cyclin, N-terminal domain HTH_23 PF13384.1 KUM59650.1 - 0.069 12.8 0.0 0.25 11.0 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain DZR PF12773.2 KUM59650.1 - 0.11 12.3 1.3 0.5 10.2 0.1 2.4 2 0 0 2 2 2 0 Double zinc ribbon Sigma70_r4_2 PF08281.7 KUM59650.1 - 0.16 11.4 0.0 0.47 9.9 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 DUF1610 PF07754.6 KUM59650.1 - 0.54 10.4 3.3 2.9 8.0 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-ribbon_3 PF13248.1 KUM59650.1 - 3.5 6.9 5.7 0.54 9.5 1.0 2.0 2 0 0 2 2 2 0 zinc-ribbon domain ATP_sub_h PF10775.4 KUM59651.1 - 6.5e-27 93.0 1.4 9.5e-27 92.5 1.0 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 KUM59651.1 - 0.00013 21.8 0.1 0.00018 21.3 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 DOR PF14839.1 KUM59651.1 - 0.096 12.4 2.2 0.15 11.7 0.3 1.8 1 1 1 2 2 2 0 DOR family Fungal_trans PF04082.13 KUM59652.1 - 5e-05 22.3 0.1 0.0001 21.2 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM59652.1 - 0.00029 20.6 11.8 0.00042 20.1 5.4 2.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RasGEF PF00617.14 KUM59653.1 - 4.8e-44 150.3 0.3 7.2e-44 149.7 0.2 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KUM59653.1 - 2.7e-13 49.9 1.1 5.6e-13 48.8 0.7 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif Peptidase_M13_N PF05649.8 KUM59654.1 - 4.9e-89 299.0 0.0 7e-89 298.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 KUM59654.1 - 4.1e-55 186.1 0.0 6.5e-55 185.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 FMN_dh PF01070.13 KUM59656.1 - 6.4e-116 387.0 0.0 7.9e-116 386.7 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KUM59656.1 - 1.1e-06 27.8 0.0 2.7e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.20 KUM59656.1 - 5.6e-06 25.4 1.4 4.3e-05 22.5 0.2 2.6 3 1 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 KUM59656.1 - 0.00064 19.0 0.2 0.11 11.7 0.0 2.6 2 1 1 3 3 3 2 Histidine biosynthesis protein NMO PF03060.10 KUM59656.1 - 0.022 13.9 0.5 0.037 13.1 0.1 1.5 2 0 0 2 2 2 0 Nitronate monooxygenase ThiG PF05690.9 KUM59656.1 - 0.068 12.2 0.1 2.3 7.2 0.0 2.4 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 KUM59656.1 - 0.077 11.9 0.1 0.87 8.4 0.0 2.1 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase CutC PF03932.9 KUM59656.1 - 0.089 12.0 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 CutC family MFS_1 PF07690.11 KUM59657.1 - 1.4e-15 56.9 18.2 1.4e-15 56.9 12.6 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2207 PF09972.4 KUM59657.1 - 2.3 6.6 4.8 0.43 9.0 0.0 2.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) HMG_CoA_synt_C PF08540.5 KUM59658.1 - 5.3e-104 347.6 0.5 6.7e-104 347.3 0.4 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KUM59658.1 - 3.4e-93 309.9 0.2 5.8e-93 309.2 0.2 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal TFR_dimer PF04253.10 KUM59659.1 - 8.2e-32 109.4 0.1 1.7e-31 108.4 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 KUM59659.1 - 1.1e-14 54.6 0.0 2.2e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KUM59659.1 - 2.4e-06 27.1 0.0 4.5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 KUM59659.1 - 0.00077 19.0 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 KUM59659.1 - 0.11 11.6 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 Nicastrin BCL_N PF04714.8 KUM59660.1 - 0.036 13.6 0.0 0.091 12.3 0.0 1.7 1 0 0 1 1 1 0 BCL7, N-terminal conserver region DUF364 PF04016.7 KUM59660.1 - 0.092 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF364) Fungal_trans PF04082.13 KUM59665.1 - 1.4e-16 60.1 0.1 3.4e-16 58.8 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM59665.1 - 1e-05 25.3 9.2 2.1e-05 24.3 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3597 PF12200.3 KUM59665.1 - 0.059 13.7 0.0 0.32 11.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Peptidase_M19 PF01244.16 KUM59666.1 - 9e-101 336.9 0.0 1.1e-100 336.7 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Smg4_UPF3 PF03467.10 KUM59667.1 - 2.8e-21 76.3 0.0 1.2e-20 74.2 0.0 2.1 1 1 0 1 1 1 1 Smg-4/UPF3 family RRM_6 PF14259.1 KUM59667.1 - 6.7e-08 32.4 0.0 1.6e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KUM59667.1 - 1.4e-06 27.8 0.0 5.1e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM59667.1 - 6.4e-05 22.7 0.0 0.00017 21.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nexin_C PF08628.7 KUM59667.1 - 0.22 11.5 0.6 0.67 10.0 0.4 1.8 1 0 0 1 1 1 0 Sorting nexin C terminal FAD_binding_3 PF01494.14 KUM59668.1 - 2.1e-79 267.1 0.0 2.6e-79 266.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KUM59668.1 - 1.8e-49 167.6 0.0 2.8e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.12 KUM59668.1 - 0.00014 21.0 0.0 0.00026 20.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KUM59668.1 - 0.00019 20.4 0.1 0.00047 19.1 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KUM59668.1 - 0.00022 21.1 0.1 0.00068 19.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KUM59668.1 - 0.00022 20.2 0.0 0.00041 19.3 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KUM59668.1 - 0.00076 19.4 0.5 0.0032 17.3 0.4 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KUM59668.1 - 0.0095 15.0 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KUM59668.1 - 0.028 13.4 0.0 5.8 5.8 0.0 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 KUM59668.1 - 0.029 14.7 0.0 0.085 13.2 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KUM59668.1 - 0.036 12.6 0.0 0.051 12.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase SE PF08491.5 KUM59668.1 - 0.039 12.7 0.0 0.19 10.4 0.0 1.9 1 1 0 1 1 1 0 Squalene epoxidase HI0933_like PF03486.9 KUM59668.1 - 0.089 11.2 0.1 0.13 10.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Fungal_trans_2 PF11951.3 KUM59669.1 - 0.0016 17.1 1.3 0.0017 17.0 0.9 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Lactonase PF10282.4 KUM59670.1 - 2.6e-19 69.5 0.0 3.5e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Metallophos PF00149.23 KUM59671.1 - 0.0047 16.3 0.0 0.0078 15.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.23 KUM59672.1 - 1.1e-07 31.4 0.0 1.4e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SART-1 PF03343.8 KUM59673.1 - 0.092 11.0 9.6 0.1 10.9 6.7 1.0 1 0 0 1 1 1 0 SART-1 family DUF3774 PF12609.3 KUM59673.1 - 0.68 10.8 3.1 0.76 10.6 2.1 1.2 1 0 0 1 1 1 0 Wound-induced protein NST1 PF13945.1 KUM59673.1 - 2.3 8.2 11.0 2.6 8.0 7.7 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Glyco_hydro_7 PF00840.15 KUM59674.1 - 1.7e-219 728.5 19.0 1.7e-219 728.5 13.2 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 KUM59674.1 - 1.2e-12 47.1 11.7 1.2e-12 47.1 8.1 4.0 5 1 0 5 5 5 1 Fungal cellulose binding domain Sporozoite_P67 PF05642.6 KUM59674.1 - 0.56 7.9 10.0 0.84 7.4 6.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cellulase PF00150.13 KUM59675.1 - 4.1e-46 157.4 1.9 5.3e-46 157.0 1.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KUM59675.1 - 4.6e-13 48.5 9.4 4.6e-13 48.5 6.5 3.2 4 0 0 4 4 4 1 Fungal cellulose binding domain MFS_1 PF07690.11 KUM59676.1 - 9.1e-15 54.2 19.4 1.1e-13 50.6 13.8 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily Peptidase_M20 PF01546.23 KUM59677.1 - 9.5e-07 28.4 0.0 1.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Sua5_yciO_yrdC PF01300.13 KUM59678.1 - 4.3e-10 39.1 0.0 6e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination Peptidase_A4 PF01828.12 KUM59679.1 - 7.2e-80 266.9 6.5 8.7e-80 266.6 4.5 1.1 1 0 0 1 1 1 1 Peptidase A4 family DUF2753 PF10952.3 KUM59680.1 - 0.044 13.7 0.1 0.048 13.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2753) M20_dimer PF07687.9 KUM59682.1 - 0.00012 21.7 0.0 0.00031 20.4 0.0 1.6 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M35 PF02102.10 KUM59684.1 - 2.4e-174 579.1 15.9 2.7e-174 578.9 11.0 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 KUM59684.1 - 1.4e-05 25.6 1.8 1.4e-05 25.6 1.2 1.7 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase CARDB PF07705.6 KUM59684.1 - 0.046 13.7 0.1 0.2 11.7 0.0 2.1 1 1 0 1 1 1 0 CARDB HMGL-like PF00682.14 KUM59684.1 - 0.062 12.9 0.2 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 HMGL-like Peptidase_M91 PF14891.1 KUM59684.1 - 0.11 12.4 0.1 0.21 11.6 0.0 1.4 1 1 0 1 1 1 0 Effector protein Methyltransf_23 PF13489.1 KUM59686.1 - 1.1e-11 44.7 0.0 1.5e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM59686.1 - 4.9e-08 33.5 0.0 5.7e-07 30.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM59686.1 - 0.00028 21.2 0.0 0.0047 17.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM59686.1 - 0.00038 20.0 0.0 0.0041 16.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM59686.1 - 0.0017 18.8 0.0 0.0049 17.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KUM59686.1 - 0.0026 16.8 0.0 0.0054 15.7 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase CheR PF01739.13 KUM59686.1 - 0.0027 17.0 0.0 0.0055 15.9 0.0 1.4 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_26 PF13659.1 KUM59686.1 - 0.026 14.5 0.0 0.055 13.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 KUM59686.1 - 0.029 14.7 0.0 0.47 10.8 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Transp_cyt_pur PF02133.10 KUM59687.1 - 2.9e-81 273.2 25.0 4.6e-77 259.4 11.3 2.0 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1485 PF07364.7 KUM59688.1 - 3.4e-72 243.1 0.1 4.5e-72 242.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1485) MlrC_C PF07171.7 KUM59688.1 - 4.5e-40 137.0 0.0 9.4e-40 136.0 0.0 1.5 1 0 0 1 1 1 1 MlrC C-terminus Formyl_trans_N PF00551.14 KUM59689.1 - 2.2e-39 134.8 0.2 2.8e-39 134.5 0.2 1.1 1 0 0 1 1 1 1 Formyl transferase ACT_6 PF13740.1 KUM59689.1 - 4.8e-09 35.8 0.1 1.1e-07 31.4 0.0 2.7 2 2 0 2 2 2 1 ACT domain ACT PF01842.20 KUM59689.1 - 3.6e-08 32.7 0.1 1.6e-07 30.6 0.0 2.2 2 0 0 2 2 2 1 ACT domain NUDIX PF00293.23 KUM59690.1 - 2.4e-11 43.4 0.0 3.2e-11 42.9 0.0 1.3 1 1 0 1 1 1 1 NUDIX domain Abhydrolase_6 PF12697.2 KUM59691.1 - 5e-27 95.2 0.3 5e-27 95.2 0.2 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM59691.1 - 4e-12 46.1 0.0 3.3e-11 43.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KUM59691.1 - 6.5e-12 45.4 0.1 6.5e-11 42.1 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KUM59691.1 - 6.4e-06 24.8 0.0 9.3e-06 24.3 0.0 1.2 1 0 0 1 1 1 1 Ndr family Esterase PF00756.15 KUM59691.1 - 0.01 15.2 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Abhydrolase_4 PF08386.5 KUM59691.1 - 0.1 12.5 0.0 0.5 10.2 0.0 2.1 2 0 0 2 2 2 0 TAP-like protein CMD PF02627.15 KUM59692.1 - 2.8e-09 36.6 0.1 3.4e-08 33.2 0.1 2.2 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family bZIP_1 PF00170.16 KUM59693.1 - 5.2e-09 35.9 12.6 6.8e-08 32.3 6.8 2.6 2 1 0 2 2 2 1 bZIP transcription factor Adeno_PIX PF03955.9 KUM59693.1 - 0.0096 16.4 0.2 0.022 15.2 0.0 1.7 2 0 0 2 2 2 1 Adenovirus hexon-associated protein (IX) Rab5-bind PF09311.6 KUM59693.1 - 0.028 14.3 0.7 0.048 13.5 0.5 1.4 1 0 0 1 1 1 0 Rabaptin-like protein BLOC1_2 PF10046.4 KUM59693.1 - 0.048 13.7 0.7 0.089 12.9 0.5 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Glutaredoxin2_C PF04399.8 KUM59693.1 - 0.054 13.0 0.1 0.13 11.8 0.1 1.6 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain bZIP_2 PF07716.10 KUM59693.1 - 0.058 13.2 12.0 2.6 7.9 7.0 3.0 2 1 0 2 2 2 0 Basic region leucine zipper Vps51 PF08700.6 KUM59693.1 - 0.078 12.8 0.3 0.14 12.0 0.2 1.5 1 0 0 1 1 1 0 Vps51/Vps67 DUF972 PF06156.8 KUM59693.1 - 0.12 12.7 0.4 0.12 12.7 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Peptidase_M20 PF01546.23 KUM59694.1 - 1.8e-09 37.3 0.3 3.1e-09 36.6 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KUM59694.1 - 1.7e-08 34.1 0.0 5.1e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Fungal_trans_2 PF11951.3 KUM59695.1 - 2.4e-48 164.6 3.5 3e-48 164.3 2.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Antimicrobial_9 PF08104.6 KUM59695.1 - 0.23 11.2 0.2 0.71 9.7 0.2 1.8 1 0 0 1 1 1 0 Ponericin L family DIOX_N PF14226.1 KUM59696.1 - 1.4e-20 73.9 0.0 2.3e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KUM59696.1 - 1.7e-15 57.1 0.0 2.5e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fructosamin_kin PF03881.9 KUM59696.1 - 0.13 11.1 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase FAD_binding_3 PF01494.14 KUM59700.1 - 3e-23 82.4 0.0 3.8e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KUM59700.1 - 3.8e-08 32.6 0.9 4.3e-06 25.8 0.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KUM59700.1 - 2.9e-05 24.3 0.3 0.00071 19.9 0.3 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KUM59700.1 - 6.8e-05 21.8 2.1 0.00094 18.1 0.6 2.2 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.9 KUM59700.1 - 0.0075 14.9 0.7 6 5.3 0.2 3.0 3 0 0 3 3 3 2 Tryptophan halogenase FAD_oxidored PF12831.2 KUM59700.1 - 0.0094 15.0 0.7 0.019 14.0 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KUM59700.1 - 0.021 14.8 0.3 0.059 13.3 0.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KUM59700.1 - 0.026 14.4 0.2 0.041 13.7 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KUM59700.1 - 0.076 12.6 0.4 0.15 11.6 0.2 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 KUM59700.1 - 0.094 11.7 0.4 0.17 10.9 0.2 1.4 1 1 0 1 1 1 0 Thi4 family ApbA PF02558.11 KUM59700.1 - 0.095 12.1 0.2 0.21 11.0 0.1 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA peroxidase PF00141.18 KUM59701.1 - 5.7e-82 274.6 0.0 6.3e-44 150.1 0.0 2.3 2 0 0 2 2 2 2 Peroxidase MFS_1 PF07690.11 KUM59702.1 - 6.2e-26 90.9 34.4 6.2e-26 90.9 23.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1258 PF06869.7 KUM59702.1 - 0.02 13.9 0.1 0.054 12.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1258) P5CR_dimer PF14748.1 KUM59704.1 - 2e-37 127.4 0.4 4.3e-37 126.4 0.3 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KUM59704.1 - 9.6e-17 61.2 0.3 2.2e-16 60.0 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 KUM59704.1 - 1.6e-05 24.6 1.5 0.0003 20.5 1.0 2.2 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 KUM59704.1 - 0.03 13.7 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 KUM59704.1 - 0.039 13.7 0.0 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 KUM59704.1 - 0.042 13.9 0.1 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase CoA_binding_2 PF13380.1 KUM59704.1 - 0.11 12.6 0.1 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain PDH PF02153.12 KUM59704.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase DUF2296 PF10058.4 KUM59705.1 - 1e-19 69.9 0.3 1.7e-19 69.3 0.2 1.3 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) DUF3279 PF11682.3 KUM59705.1 - 0.11 12.1 0.9 0.26 10.8 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3279) Ribonuclease_3 PF00636.21 KUM59706.1 - 4e-43 146.4 0.0 5.6e-22 78.3 0.0 3.3 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KUM59706.1 - 2.1e-29 102.0 0.0 4e-14 52.6 0.0 3.6 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.9 KUM59706.1 - 5.6e-26 90.1 0.0 1.8e-25 88.5 0.0 2.0 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.24 KUM59706.1 - 4.8e-17 61.9 0.0 1.3e-16 60.5 0.0 1.8 1 1 1 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM59706.1 - 6e-16 58.0 0.0 2e-15 56.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KUM59706.1 - 9.7e-11 41.8 0.0 2.6e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 KUM59706.1 - 0.038 13.2 0.0 0.082 12.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein UvrD-helicase PF00580.16 KUM59706.1 - 0.16 11.2 0.5 0.66 9.2 0.0 2.0 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF1686 PF07937.6 KUM59709.1 - 0.014 15.0 0.4 0.024 14.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1686) DUF2975 PF11188.3 KUM59709.1 - 0.84 9.3 8.0 0.13 11.9 1.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) GMC_oxred_N PF00732.14 KUM59710.1 - 4.5e-55 186.8 0.0 6e-55 186.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KUM59710.1 - 4.2e-33 114.6 0.1 7.5e-33 113.8 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KUM59710.1 - 4.1e-09 35.8 0.1 0.00046 19.2 0.0 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KUM59710.1 - 9.9e-06 24.7 0.0 1.7e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KUM59710.1 - 3.4e-05 23.7 0.1 9.4e-05 22.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KUM59710.1 - 0.00089 18.2 0.1 0.58 8.9 0.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KUM59710.1 - 0.0013 17.6 0.1 0.0095 14.8 0.0 2.2 2 1 1 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.9 KUM59710.1 - 0.0019 18.1 0.0 0.0083 16.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KUM59710.1 - 0.0062 15.0 0.0 0.057 11.8 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 KUM59710.1 - 0.012 15.3 0.0 0.03 14.0 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KUM59710.1 - 0.021 14.8 0.0 0.32 11.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Gal-bind_lectin PF00337.17 KUM59710.1 - 0.073 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Galactoside-binding lectin FAD_oxidored PF12831.2 KUM59710.1 - 0.43 9.6 2.7 0.75 8.8 0.5 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Fungal_trans PF04082.13 KUM59713.1 - 1.2e-15 57.1 1.8 1.7e-15 56.5 0.1 1.8 2 1 1 3 3 3 1 Fungal specific transcription factor domain ECH PF00378.15 KUM59714.1 - 2.8e-41 141.2 0.1 4.3e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family HMGL-like PF00682.14 KUM59714.1 - 1.3e-39 136.3 0.0 1.9e-39 135.7 0.0 1.3 1 0 0 1 1 1 1 HMGL-like AMP-binding PF00501.23 KUM59715.1 - 3.9e-88 295.6 0.1 4.7e-88 295.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KUM59715.1 - 1.8e-13 51.1 0.0 5.3e-13 49.7 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 KUM59716.1 - 7.8e-33 113.6 24.6 8.4e-33 113.5 16.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Rick_17kDa_Anti PF05433.10 KUM59716.1 - 0.028 14.0 0.4 0.028 14.0 0.3 1.7 2 0 0 2 2 2 0 Glycine zipper 2TM domain Ribosomal_L19 PF01245.15 KUM59717.1 - 4.5e-18 65.0 1.1 7.3e-18 64.4 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 AMP-binding PF00501.23 KUM59719.1 - 1.8e-13 49.7 0.1 7.1e-09 34.5 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme NPCC PF08058.6 KUM59720.1 - 8.3e-36 122.9 0.2 2e-34 118.4 0.2 2.1 1 1 0 1 1 1 1 Nuclear pore complex component CytochromB561_N PF09786.4 KUM59720.1 - 0.0018 16.7 1.7 0.0022 16.5 1.2 1.1 1 0 0 1 1 1 1 Cytochrome B561, N terminal Hid1 PF12722.2 KUM59721.1 - 3.4e-281 935.0 0.0 5.4e-281 934.3 0.0 1.3 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 KUM59721.1 - 5e-77 259.5 0.0 7.8e-77 258.9 0.0 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein CPSase_L_D2 PF02786.12 KUM59722.1 - 1e-70 237.3 0.1 1.6e-70 236.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KUM59722.1 - 8.8e-36 122.3 0.7 2.2e-35 121.0 0.1 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KUM59722.1 - 8.5e-32 109.3 0.0 2.1e-31 108.0 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 KUM59722.1 - 2.1e-14 53.6 0.0 3.8e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KUM59722.1 - 7.2e-12 44.7 1.2 2e-11 43.3 0.9 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 KUM59722.1 - 3.5e-10 39.6 0.0 7.5e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 KUM59722.1 - 6.7e-10 38.2 0.0 1.8e-09 36.8 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KUM59722.1 - 2.2e-08 33.6 0.2 5e-08 32.4 0.2 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KUM59722.1 - 1.4e-07 31.5 0.0 2.2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KUM59722.1 - 9.6e-05 21.9 0.0 0.00026 20.5 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain SUI1 PF01253.17 KUM59722.1 - 0.021 14.6 0.0 0.054 13.2 0.0 1.7 1 0 0 1 1 1 0 Translation initiation factor SUI1 ATPgrasp_YheCD PF14398.1 KUM59722.1 - 0.046 12.5 0.0 0.19 10.5 0.0 1.8 2 0 0 2 2 2 0 YheC/D like ATP-grasp Biotin_lipoyl_2 PF13533.1 KUM59722.1 - 0.052 13.2 0.0 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 Biotin-lipoyl like NUMOD3 PF07460.6 KUM59722.1 - 0.098 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 NUMOD3 motif (2 copies) HlyD_3 PF13437.1 KUM59722.1 - 0.12 12.7 0.2 0.89 9.9 0.0 2.6 3 0 0 3 3 3 0 HlyD family secretion protein ABC2_membrane PF01061.19 KUM59724.1 - 5.1e-86 287.1 58.4 2.2e-45 154.4 10.6 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KUM59724.1 - 3.8e-35 121.1 0.0 2.2e-17 63.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KUM59724.1 - 9.4e-28 95.8 0.5 6.8e-23 80.3 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KUM59724.1 - 4.1e-07 30.0 0.0 1.4e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KUM59724.1 - 3.3e-05 23.3 0.1 0.0027 17.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 KUM59724.1 - 5.8e-05 22.9 0.0 0.0051 16.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 KUM59724.1 - 0.00021 20.4 55.5 0.001 18.1 9.0 3.1 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_17 PF13207.1 KUM59724.1 - 0.00024 21.9 0.0 0.04 14.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KUM59724.1 - 0.00032 20.1 0.3 0.0035 16.8 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KUM59724.1 - 0.00069 19.7 0.0 0.17 12.0 0.0 3.2 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 KUM59724.1 - 0.00096 18.3 0.1 0.0029 16.8 0.0 1.7 2 0 0 2 2 1 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 KUM59724.1 - 0.0016 18.4 0.1 0.071 13.0 0.0 3.3 4 0 0 4 4 3 1 AAA domain AAA_19 PF13245.1 KUM59724.1 - 0.0016 18.1 0.5 3.3 7.5 0.6 2.6 2 0 0 2 2 2 2 Part of AAA domain cobW PF02492.14 KUM59724.1 - 0.0027 17.1 1.9 0.011 15.2 0.5 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 KUM59724.1 - 0.0036 17.3 0.8 0.16 11.9 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KUM59724.1 - 0.004 17.4 0.0 0.088 13.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KUM59724.1 - 0.0066 16.4 0.2 0.021 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 KUM59724.1 - 0.009 15.6 0.9 1 9.0 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 KUM59724.1 - 0.045 13.4 0.0 5.5 6.6 0.0 2.8 2 0 0 2 2 2 0 Archaeal ATPase SMC_N PF02463.14 KUM59724.1 - 0.047 12.9 0.0 2.6 7.2 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain PduV-EutP PF10662.4 KUM59724.1 - 0.068 12.6 0.2 1.9 7.9 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 KUM59724.1 - 0.074 12.6 0.6 5.6 6.6 0.2 2.4 2 0 0 2 2 2 0 NACHT domain Miro PF08477.8 KUM59724.1 - 0.09 13.2 0.0 13 6.2 0.0 3.0 2 0 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 KUM59724.1 - 0.23 10.8 0.0 25 4.2 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.1 KUM59724.1 - 0.41 10.9 0.0 0.41 10.9 0.0 2.9 4 0 0 4 4 2 0 AAA domain SIMPL PF04402.9 KUM59725.1 - 3.5e-25 89.0 0.0 2.2e-24 86.5 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF541) SlyX PF04102.7 KUM59725.1 - 0.37 11.2 2.9 15 6.0 0.2 3.2 3 0 0 3 3 3 0 SlyX Thioredoxin PF00085.15 KUM59726.1 - 1.4e-27 95.3 0.2 1.8e-27 95.0 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KUM59726.1 - 2.1e-08 34.1 0.1 4.6e-07 29.8 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KUM59726.1 - 1.2e-07 31.8 0.1 1.1e-06 28.8 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 KUM59726.1 - 2e-05 24.1 0.2 0.00016 21.2 0.1 2.0 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.16 KUM59726.1 - 7.7e-05 22.3 0.0 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 KUM59726.1 - 0.00077 19.4 0.1 0.0017 18.3 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 KUM59726.1 - 0.0014 18.1 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_4 PF13462.1 KUM59726.1 - 0.0092 16.0 0.3 3.1 7.7 0.0 2.6 1 1 2 3 3 3 2 Thioredoxin TraF PF13728.1 KUM59726.1 - 0.011 15.2 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_5 PF13743.1 KUM59726.1 - 0.027 14.0 0.1 0.15 11.6 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin Phosducin PF02114.11 KUM59726.1 - 0.03 13.0 0.0 0.034 12.8 0.0 1.2 1 0 0 1 1 1 0 Phosducin DSBA PF01323.15 KUM59726.1 - 0.075 12.5 0.4 2 7.9 0.0 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Carboxyl_trans PF01039.17 KUM59727.1 - 1.6e-115 386.3 0.0 1.9e-115 386.0 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain KAT11 PF08214.6 KUM59729.1 - 7.9e-104 347.4 0.0 1.1e-103 346.9 0.0 1.2 1 0 0 1 1 1 1 Histone acetylation protein Ank_2 PF12796.2 KUM59730.1 - 7.1e-16 58.3 1.1 1.7e-15 57.1 0.6 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 KUM59730.1 - 2.5e-15 55.4 0.6 9.4e-12 44.1 0.1 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 KUM59730.1 - 4.1e-14 52.6 1.2 2.9e-08 34.0 0.1 3.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM59730.1 - 1e-13 51.0 4.1 2e-10 40.5 0.9 3.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM59730.1 - 1.3e-10 40.4 0.4 9.5e-08 31.5 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Glyco_transf_21 PF13506.1 KUM59731.1 - 5.6e-12 45.2 0.2 4.4e-05 22.8 0.0 3.5 1 1 1 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 KUM59731.1 - 8.1e-12 45.4 0.0 2.1e-11 44.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KUM59731.1 - 0.0013 18.4 0.0 0.0034 17.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Mito_carr PF00153.22 KUM59732.1 - 1.5e-55 184.8 0.3 5.2e-19 67.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Acyl-CoA_dh_1 PF00441.19 KUM59733.1 - 1.2e-29 103.3 1.2 1.9e-29 102.6 0.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KUM59733.1 - 1.6e-20 72.3 1.2 2.7e-20 71.5 0.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KUM59733.1 - 2.2e-20 73.3 0.0 5.1e-19 68.9 0.0 2.5 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KUM59733.1 - 0.00058 20.1 0.6 0.00083 19.6 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DAGAT PF03982.8 KUM59733.1 - 0.06 12.0 0.1 0.093 11.4 0.0 1.2 1 0 0 1 1 1 0 Diacylglycerol acyltransferase DEAD PF00270.24 KUM59734.1 - 4e-44 150.0 0.0 7.1e-44 149.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM59734.1 - 4.5e-21 74.4 0.1 1.1e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 KUM59734.1 - 1.5e-20 72.7 3.7 4e-20 71.3 2.6 1.8 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.10 KUM59734.1 - 0.00041 20.2 0.1 0.002 17.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RPA_C PF08784.6 KUM59735.1 - 1.1e-20 73.9 0.3 3.6e-20 72.2 0.0 2.0 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 KUM59735.1 - 0.0002 21.1 0.3 0.00055 19.7 0.2 1.8 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain MatE PF01554.13 KUM59736.1 - 3.9e-56 189.1 26.1 6.7e-31 107.0 6.3 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 KUM59736.1 - 2.1e-05 24.3 6.1 2.1e-05 24.3 4.2 3.5 2 1 0 2 2 2 2 Polysaccharide biosynthesis C-terminal domain DUF202 PF02656.10 KUM59737.1 - 6.9e-21 74.2 3.4 8e-21 74.0 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Yip1 PF04893.12 KUM59737.1 - 0.05 13.0 2.0 0.087 12.3 1.1 1.6 1 1 0 1 1 1 0 Yip1 domain DUF4131 PF13567.1 KUM59737.1 - 0.084 12.2 3.1 0.12 11.7 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) COX4_pro_2 PF07835.7 KUM59737.1 - 0.1 12.5 0.3 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV DUF2499 PF10693.4 KUM59737.1 - 0.19 11.8 1.2 0.26 11.3 0.2 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2499) NUDIX PF00293.23 KUM59738.1 - 3.8e-27 94.5 0.0 5.4e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain TauD PF02668.11 KUM59739.1 - 1.6e-51 175.4 0.1 2e-51 175.1 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FMO-like PF00743.14 KUM59740.1 - 3.9e-36 124.3 0.0 4.8e-21 74.5 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KUM59740.1 - 1.9e-18 67.2 0.4 2.4e-17 63.6 0.3 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM59740.1 - 2.8e-11 43.4 0.2 8.7e-09 35.3 0.2 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KUM59740.1 - 7.5e-10 39.0 0.0 2.7e-08 33.9 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KUM59740.1 - 3.1e-08 32.9 1.6 1.6e-05 23.9 0.0 3.2 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KUM59740.1 - 2.3e-07 30.7 0.8 8e-07 28.9 0.0 2.4 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KUM59740.1 - 3.6e-07 29.4 4.4 1.7e-05 23.9 2.7 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KUM59740.1 - 2.5e-06 27.7 2.4 0.00074 19.8 0.7 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KUM59740.1 - 1.7e-05 24.1 0.8 0.036 13.1 0.3 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase ApbA PF02558.11 KUM59740.1 - 4.2e-05 23.0 0.0 0.032 13.6 0.0 3.6 4 0 0 4 4 4 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 KUM59740.1 - 0.00087 18.4 1.7 0.0014 17.7 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KUM59740.1 - 0.0021 17.2 0.8 0.0042 16.2 0.5 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 KUM59740.1 - 0.0034 16.5 0.0 0.0052 15.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KUM59740.1 - 0.0095 14.4 2.0 0.019 13.4 1.4 1.5 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_2 PF03446.10 KUM59740.1 - 0.022 14.6 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 KUM59740.1 - 0.025 14.2 2.6 0.044 13.4 1.8 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KUM59740.1 - 0.034 14.2 2.3 0.61 10.1 0.4 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 KUM59740.1 - 0.044 12.6 0.0 0.094 11.5 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 KUM59740.1 - 0.052 12.9 1.4 0.11 11.9 0.6 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.1 KUM59740.1 - 0.056 13.4 0.3 0.18 11.7 0.3 1.7 2 0 0 2 2 1 0 NADH(P)-binding GIDA PF01134.17 KUM59740.1 - 1.1 8.0 2.7 1.9 7.2 1.8 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Ost4 PF10215.4 KUM59742.1 - 1.2e-18 66.2 1.6 1.6e-18 65.9 1.1 1.2 1 0 0 1 1 1 1 Oligosaccaryltransferase Fungal_trans PF04082.13 KUM59743.1 - 2.8e-10 39.4 0.0 4.1e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM59743.1 - 3.2e-10 39.7 9.5 5e-10 39.1 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RabGAP-TBC PF00566.13 KUM59745.1 - 1e-41 142.8 0.0 5.8e-40 137.0 0.0 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain TPR_MLP1_2 PF07926.7 KUM59745.1 - 0.1 12.3 0.3 0.37 10.5 0.1 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein adh_short PF00106.20 KUM59746.1 - 2.1e-27 96.0 1.2 3.6e-27 95.3 0.8 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM59746.1 - 2.9e-26 92.7 0.1 3.4e-26 92.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM59746.1 - 8.5e-10 38.5 0.8 3e-09 36.7 0.6 1.8 1 1 0 1 1 1 1 KR domain DENN PF02141.16 KUM59747.1 - 6.1e-40 136.9 0.1 1.1e-39 136.0 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 KUM59747.1 - 0.00036 20.4 0.0 0.0011 18.8 0.0 1.9 1 0 0 1 1 1 1 uDENN domain Elongin_A PF06881.6 KUM59747.1 - 0.012 15.9 5.2 0.012 15.9 3.6 2.7 2 1 1 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A IncA PF04156.9 KUM59747.1 - 0.13 11.8 18.6 0.14 11.7 5.0 2.7 1 1 1 2 2 2 0 IncA protein DivIVA PF05103.8 KUM59747.1 - 1.1 9.3 13.3 0.14 12.2 3.7 2.8 1 1 1 2 2 2 0 DivIVA protein DUF2570 PF10828.3 KUM59747.1 - 5.4 6.6 9.1 3 7.4 4.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) Microtub_assoc PF07989.6 KUM59747.1 - 6.1 6.7 10.4 0.6 9.9 1.3 2.8 2 1 0 2 2 2 0 Microtubule associated Pkinase PF00069.20 KUM59748.1 - 3.6e-23 82.0 0.0 5.6e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 KUM59748.1 - 7.4e-14 51.0 7.1 1.4e-09 37.4 0.1 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat HEAT PF02985.17 KUM59748.1 - 5.3e-11 41.6 4.4 0.014 15.3 0.0 6.8 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 KUM59748.1 - 1.6e-05 25.0 0.7 3.1 8.1 0.0 4.2 1 1 2 3 3 3 3 HEAT repeats Pkinase_Tyr PF07714.12 KUM59748.1 - 0.00069 18.7 0.0 0.0013 17.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase DUF2454 PF10521.4 KUM59748.1 - 0.035 13.1 0.0 0.077 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2454) HEAT_EZ PF13513.1 KUM59748.1 - 0.09 13.2 4.9 0.15 12.5 0.3 3.5 3 0 0 3 3 3 0 HEAT-like repeat zf-C2H2_4 PF13894.1 KUM59751.1 - 7.5e-10 38.4 8.3 0.00011 22.2 1.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KUM59751.1 - 1.8e-09 37.3 11.9 1.4e-05 25.1 1.4 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KUM59751.1 - 0.0013 18.8 16.3 0.16 12.2 6.5 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 KUM59751.1 - 0.0035 17.4 7.2 0.69 10.2 1.1 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KUM59751.1 - 0.0038 17.3 6.0 0.053 13.6 0.3 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KUM59751.1 - 0.041 13.8 6.0 1.6 8.7 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 KUM59751.1 - 0.077 13.1 4.3 0.12 12.4 3.0 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 KUM59751.1 - 1 9.4 7.1 8.8 6.5 1.4 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.6 KUM59751.1 - 2.2 8.0 4.5 1 9.1 0.2 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Nsp1_C PF05064.8 KUM59752.1 - 0.06 12.9 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 Nsp1-like C-terminal region Chorismate_bind PF00425.13 KUM59754.1 - 1.8e-61 207.7 0.0 2.5e-59 200.6 0.0 2.5 2 1 0 2 2 2 1 chorismate binding enzyme GATase PF00117.23 KUM59754.1 - 1.6e-29 102.7 0.0 2.6e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 KUM59754.1 - 5.2e-13 49.2 0.0 1.3e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 KUM59754.1 - 2.8e-05 23.6 0.0 6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 COesterase PF00135.23 KUM59755.1 - 1.5e-68 231.8 0.0 2e-68 231.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KUM59755.1 - 4.2e-08 33.0 0.0 0.001 18.7 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KUM59755.1 - 0.032 13.9 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Zn_clus PF00172.13 KUM59756.1 - 8.1e-07 28.8 7.3 8.1e-07 28.8 5.1 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Actin PF00022.14 KUM59757.1 - 1.7e-139 464.6 0.0 2e-139 464.4 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KUM59757.1 - 0.08 13.3 0.1 0.25 11.7 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Pet127 PF08634.5 KUM59758.1 - 3.9e-120 400.1 1.7 5.7e-120 399.5 1.2 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 GARS_A PF01071.14 KUM59759.1 - 1.4e-81 272.7 0.0 2.1e-81 272.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 KUM59759.1 - 5.8e-34 116.5 0.0 2.5e-33 114.5 0.0 2.2 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 KUM59759.1 - 1.3e-29 103.1 0.0 3.3e-29 101.8 0.0 1.7 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 KUM59759.1 - 1.5e-26 92.3 0.1 3.4e-26 91.2 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 KUM59759.1 - 3e-16 59.4 1.0 1.1e-15 57.5 0.7 2.0 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 KUM59759.1 - 5.4e-09 36.0 0.0 1.5e-08 34.5 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KUM59759.1 - 2.9e-08 32.8 0.0 5.4e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KUM59759.1 - 3.9e-05 23.0 0.0 7.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_2 PF08442.5 KUM59759.1 - 0.00016 21.0 0.0 0.00088 18.7 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.12 KUM59759.1 - 0.00052 19.3 0.0 0.001 18.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 KUM59759.1 - 0.00086 19.1 0.1 0.0043 16.9 0.0 2.1 2 1 0 2 2 2 1 ATP-grasp domain RimK PF08443.6 KUM59759.1 - 0.06 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 RimK-like ATP-grasp domain LRR_6 PF13516.1 KUM59760.1 - 0.03 14.3 6.3 9.3 6.6 0.0 6.3 8 0 0 8 8 8 0 Leucine Rich repeat LRR_7 PF13504.1 KUM59760.1 - 4.7 7.8 9.8 16 6.2 0.1 6.2 8 0 0 8 8 8 0 Leucine rich repeat TRAPPC9-Trs120 PF08626.6 KUM59761.1 - 1.4e-154 516.2 0.0 1.7e-154 515.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Fes1 PF08609.5 KUM59762.1 - 1.1e-33 115.5 3.2 2.6e-33 114.3 0.9 2.1 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 KUM59762.1 - 1.6e-09 37.8 0.5 8.3e-06 26.0 0.1 2.4 1 1 1 2 2 2 2 HEAT repeats Arm PF00514.18 KUM59762.1 - 6.2e-08 32.1 0.1 0.00062 19.5 0.0 2.4 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 KUM59762.1 - 3.3e-06 27.4 0.3 0.0061 17.0 0.0 3.0 2 1 1 3 3 3 2 HEAT-like repeat HEAT PF02985.17 KUM59762.1 - 0.00047 19.9 0.1 0.01 15.8 0.0 2.5 2 0 0 2 2 2 1 HEAT repeat CTNNBL PF08216.6 KUM59762.1 - 0.00055 19.4 0.6 0.0085 15.6 0.2 2.3 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Atx10homo_assoc PF09759.4 KUM59762.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain RICTOR_V PF14668.1 KUM59762.1 - 0.032 14.1 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.3 KUM59762.1 - 0.085 12.7 0.1 0.52 10.2 0.0 2.0 1 1 1 2 2 2 0 V-ATPase subunit H Aldedh PF00171.17 KUM59763.1 - 1.9e-127 425.4 0.0 2.1e-127 425.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Med6 PF04934.9 KUM59764.1 - 4.7e-42 142.8 0.1 6.2e-42 142.4 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Lysine_decarbox PF03641.9 KUM59765.1 - 2.8e-28 98.3 0.0 4.7e-28 97.6 0.0 1.4 1 1 0 1 1 1 1 Possible lysine decarboxylase DUF3684 PF12449.3 KUM59766.1 - 0 1548.7 0.0 0 1548.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 KUM59766.1 - 4.4e-05 23.1 0.0 0.00011 21.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KUM59766.1 - 0.00099 18.8 0.0 0.0039 16.8 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WLM PF08325.5 KUM59766.1 - 0.11 12.3 2.2 0.71 9.7 0.1 2.4 2 0 0 2 2 2 0 WLM domain Pheromone PF08015.6 KUM59766.1 - 2.1 9.2 5.6 2.3 9.0 1.1 3.4 2 0 0 2 2 2 0 Fungal mating-type pheromone UPF0220 PF05255.6 KUM59768.1 - 1.1e-68 229.6 2.2 1.2e-68 229.5 1.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) ATP1G1_PLM_MAT8 PF02038.11 KUM59768.1 - 0.051 12.5 1.0 0.19 10.7 0.2 2.2 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Proteasome PF00227.21 KUM59769.1 - 7e-50 168.9 0.0 8.8e-50 168.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KUM59769.1 - 2.8e-12 45.7 0.3 4.3e-12 45.1 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Vps55 PF04133.9 KUM59770.1 - 1.6e-47 160.1 5.1 1.8e-47 159.9 3.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Exo_endo_phos PF03372.18 KUM59771.1 - 5e-09 36.4 0.1 6.9e-09 36.0 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PEX11 PF05648.9 KUM59773.1 - 1.9e-77 259.5 0.2 2.1e-77 259.3 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Spore_YhaL PF14147.1 KUM59773.1 - 0.036 13.5 0.2 0.065 12.6 0.1 1.4 1 0 0 1 1 1 0 Sporulation protein YhaL DivIC PF04977.10 KUM59773.1 - 0.077 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Septum formation initiator COX14 PF14880.1 KUM59773.1 - 0.12 11.9 0.4 2.4 7.8 0.0 2.8 2 0 0 2 2 2 0 Cytochrome oxidase c assembly RPN7 PF10602.4 KUM59774.1 - 1.4e-52 177.6 0.3 2.1e-52 177.0 0.2 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KUM59774.1 - 3.7e-15 56.1 0.0 7.7e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 PCI domain Sugar_tr PF00083.19 KUM59775.1 - 7.6e-26 90.6 35.2 6.6e-18 64.5 9.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KUM59775.1 - 2.8e-16 59.1 41.1 6.9e-15 54.6 27.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PDR_CDR PF06422.7 KUM59775.1 - 1.6 8.4 4.4 4.8 6.9 0.0 3.3 3 0 0 3 3 3 0 CDR ABC transporter Fungal_trans PF04082.13 KUM59776.1 - 2.3e-16 59.4 0.1 3.4e-16 58.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM59776.1 - 6.2e-08 32.4 11.6 6.8e-08 32.2 5.4 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TaqI_C PF12950.2 KUM59776.1 - 0.2 11.3 0.0 0.42 10.3 0.0 1.4 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain RPE65 PF03055.10 KUM59777.1 - 8.8e-123 410.4 0.0 1e-122 410.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein ACT_3 PF10000.4 KUM59778.1 - 2e-18 65.8 0.1 3.3e-18 65.1 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.1 KUM59778.1 - 5.1e-11 41.9 0.0 8.3e-11 41.2 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT PF01842.20 KUM59778.1 - 0.044 13.2 0.0 0.71 9.4 0.0 2.4 3 0 0 3 3 3 0 ACT domain Zn_clus PF00172.13 KUM59780.1 - 2.3e-10 40.1 8.2 3.8e-10 39.5 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mif2_N PF15624.1 KUM59783.1 - 6.5 7.3 7.3 0.73 10.4 1.4 2.0 2 0 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal GFA PF04828.9 KUM59784.1 - 1.2e-16 60.3 0.1 1.2e-16 60.3 0.1 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme PALP PF00291.20 KUM59785.1 - 1.3e-54 185.5 0.2 1.6e-54 185.2 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PAD_porph PF04371.10 KUM59786.1 - 1.9e-65 221.0 0.0 2.3e-65 220.7 0.0 1.1 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Copper-fist PF00649.13 KUM59787.1 - 4.4e-21 73.7 3.2 4.4e-21 73.7 2.2 2.9 2 1 1 3 3 3 1 Copper fist DNA binding domain Aminotran_1_2 PF00155.16 KUM59788.1 - 4.4e-39 134.4 0.0 6.1e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II SspK PF08176.7 KUM59789.1 - 0.083 12.9 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 Small acid-soluble spore protein K family DUF2682 PF10909.3 KUM59789.1 - 0.14 12.4 0.0 0.39 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2682) His_Phos_2 PF00328.17 KUM59790.1 - 3.3e-16 59.5 0.0 4.1e-14 52.6 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) AAA PF00004.24 KUM59791.1 - 2.5e-16 60.0 0.0 4.6e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 KUM59791.1 - 2e-15 56.5 0.0 5e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KUM59791.1 - 7.5e-14 51.7 0.1 2.1e-13 50.2 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.10 KUM59791.1 - 8.4e-10 37.9 0.0 1.4e-07 30.6 0.0 2.5 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KUM59791.1 - 6.1e-08 32.8 0.2 1.4e-06 28.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KUM59791.1 - 1.1e-06 28.2 0.1 4.2e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KUM59791.1 - 2.7e-06 27.5 0.1 0.00042 20.3 0.0 2.9 2 2 1 3 3 3 1 AAA ATPase domain AAA_11 PF13086.1 KUM59791.1 - 1e-05 25.2 0.1 0.00015 21.4 0.0 2.3 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 KUM59791.1 - 1e-05 24.7 0.1 4.6e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KUM59791.1 - 2e-05 24.3 0.2 9.6e-05 22.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KUM59791.1 - 2.3e-05 24.0 0.0 4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KUM59791.1 - 4.9e-05 23.2 0.0 0.0001 22.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 KUM59791.1 - 6.1e-05 21.9 0.1 0.29 9.8 0.0 2.6 3 0 0 3 3 3 2 TIP49 C-terminus DUF815 PF05673.8 KUM59791.1 - 8.6e-05 21.5 0.0 0.00015 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DNA_pol3_delta PF06144.8 KUM59791.1 - 0.00013 21.5 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_3 PF07726.6 KUM59791.1 - 0.00023 20.7 0.1 0.0019 17.7 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KUM59791.1 - 0.00047 19.4 0.5 0.65 9.1 0.0 2.4 1 1 1 2 2 2 2 PhoH-like protein AAA_24 PF13479.1 KUM59791.1 - 0.0012 18.4 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 KUM59791.1 - 0.0014 18.1 0.1 0.05 13.1 0.0 2.5 1 1 1 2 2 2 1 DEAD/DEAH box helicase Sigma54_activat PF00158.21 KUM59791.1 - 0.0047 16.4 0.0 0.0089 15.5 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain DUF2075 PF09848.4 KUM59791.1 - 0.0058 15.6 0.0 0.0085 15.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 KUM59791.1 - 0.0073 15.7 0.5 0.02 14.2 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA_28 PF13521.1 KUM59791.1 - 0.0084 16.0 0.1 0.018 15.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KUM59791.1 - 0.015 15.6 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KUM59791.1 - 0.016 14.5 0.0 0.29 10.5 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_10 PF12846.2 KUM59791.1 - 0.017 14.6 0.2 3.7 6.8 0.0 2.4 1 1 0 2 2 2 0 AAA-like domain Arch_ATPase PF01637.13 KUM59791.1 - 0.023 14.3 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 KUM59791.1 - 0.027 15.3 0.0 0.056 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KUM59791.1 - 0.037 13.2 0.2 0.21 10.7 0.1 2.3 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KUM59791.1 - 0.037 14.2 0.0 0.13 12.4 0.0 1.9 1 1 0 1 1 1 0 RNA helicase ResIII PF04851.10 KUM59791.1 - 0.05 13.4 0.0 0.29 10.9 0.0 1.9 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 KUM59791.1 - 0.077 13.2 0.0 0.14 12.4 0.0 1.6 1 1 0 1 1 1 0 ABC transporter SNF2_N PF00176.18 KUM59791.1 - 0.11 11.2 0.0 3 6.5 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain FtsK_SpoIIIE PF01580.13 KUM59791.1 - 0.11 11.8 0.0 0.35 10.3 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Pro_isomerase PF00160.16 KUM59792.1 - 5e-39 134.0 0.0 8.8e-39 133.2 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.1 KUM59792.1 - 0.0076 16.4 0.2 0.0076 16.4 0.1 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4604) Clr5 PF14420.1 KUM59793.1 - 6.3e-10 38.8 0.2 2.8e-09 36.7 0.0 1.9 2 0 0 2 2 2 1 Clr5 domain HTH_Tnp_Tc3_2 PF01498.13 KUM59793.1 - 2.9e-05 24.0 0.6 0.0023 17.9 0.2 2.2 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.1 KUM59793.1 - 0.00044 20.9 0.7 0.028 15.2 0.1 2.2 1 1 1 2 2 2 1 Homeodomain-like domain HTH_12 PF08461.5 KUM59793.1 - 0.0029 17.3 1.8 0.57 9.9 0.1 2.3 1 1 0 2 2 2 2 Ribonuclease R winged-helix domain Sigma54_DBD PF04552.8 KUM59793.1 - 0.034 13.6 0.2 0.13 11.7 0.2 1.8 1 1 0 1 1 1 0 Sigma-54, DNA binding domain DUF4498 PF14926.1 KUM59793.1 - 0.06 12.4 0.1 0.12 11.4 0.1 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4498) DUF4609 PF15382.1 KUM59793.1 - 0.15 11.7 0.3 0.15 11.7 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4609) Aldo_ket_red PF00248.16 KUM59794.1 - 1.6e-17 63.2 0.0 3.2e-17 62.2 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family SANTA PF09133.5 KUM59794.1 - 0.041 13.8 0.0 0.092 12.7 0.0 1.6 1 0 0 1 1 1 0 SANTA (SANT Associated) HSF_DNA-bind PF00447.12 KUM59795.1 - 7.5e-29 99.9 0.1 1.4e-28 99.1 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding TMF_DNA_bd PF12329.3 KUM59795.1 - 0.021 14.6 1.5 0.55 10.0 0.1 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PhaP_Bmeg PF09602.5 KUM59795.1 - 0.094 12.5 0.6 0.19 11.5 0.4 1.4 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Ets PF00178.17 KUM59795.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Ets-domain DUF3431 PF11913.3 KUM59796.1 - 1.7e-86 289.2 1.3 2.2e-86 288.9 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Sporozoite_P67 PF05642.6 KUM59797.1 - 0.00011 20.2 8.8 0.00014 19.8 6.1 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Nucleoplasmin PF03066.10 KUM59797.1 - 0.011 15.2 1.2 0.015 14.8 0.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF4604 PF15377.1 KUM59797.1 - 0.015 15.5 0.3 0.022 14.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DUF4611 PF15387.1 KUM59797.1 - 0.025 14.6 2.3 0.055 13.6 1.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Macoilin PF09726.4 KUM59797.1 - 0.11 10.7 8.8 0.14 10.4 6.1 1.0 1 0 0 1 1 1 0 Transmembrane protein RXT2_N PF08595.6 KUM59797.1 - 0.27 11.0 2.5 0.38 10.5 1.7 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal TFIIF_alpha PF05793.7 KUM59797.1 - 0.4 8.9 10.8 0.51 8.6 7.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FAM176 PF14851.1 KUM59797.1 - 1.3 8.6 5.0 1.5 8.5 2.9 1.5 1 1 0 1 1 1 0 FAM176 family DUF2457 PF10446.4 KUM59797.1 - 3.3 6.3 14.9 4.9 5.7 10.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cwf_Cwc_15 PF04889.7 KUM59797.1 - 5.1 6.7 12.6 0.39 10.3 5.5 1.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.1 KUM59797.1 - 5.2 7.4 11.9 9.4 6.6 8.3 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Bd3614_N PF14442.1 KUM59797.1 - 5.6 6.9 11.2 2.8 7.9 6.3 1.7 1 1 0 1 1 1 0 Bd3614-like deaminase N-terminal Histone PF00125.19 KUM59798.1 - 4.4e-22 77.9 0.0 5.6e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KUM59798.1 - 5.1e-05 23.2 0.0 7.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone R3H PF01424.17 KUM59799.1 - 1.8e-10 40.3 0.1 3.7e-10 39.3 0.1 1.5 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 KUM59799.1 - 1.2e-06 28.3 0.0 2.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KUM59799.1 - 7.1e-06 25.5 0.1 1.3e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM59799.1 - 0.0082 15.9 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUZ-C PF12901.2 KUM59799.1 - 0.046 13.3 6.3 0.14 11.8 2.8 2.9 2 0 0 2 2 2 0 SUZ-C motif Bys1 PF04681.7 KUM59800.1 - 1.3e-14 54.2 1.2 1.5e-14 53.9 0.8 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Pho88 PF10032.4 KUM59801.1 - 3.8e-78 261.1 0.1 4.4e-78 260.9 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) GAD-like PF08887.6 KUM59801.1 - 0.013 15.5 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 GAD-like domain DUF2576 PF10845.3 KUM59801.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) Gp_dh_C PF02800.15 KUM59803.1 - 7.5e-75 249.6 0.0 1.1e-74 249.1 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KUM59803.1 - 1.3e-60 203.7 0.4 4e-60 202.1 0.2 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 KUM59803.1 - 0.0024 17.8 0.1 0.0086 15.9 0.0 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Cellulase PF00150.13 KUM59804.1 - 7.7e-39 133.5 0.4 3.6e-38 131.3 0.1 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.9 KUM59804.1 - 1.6e-25 88.7 9.1 1.1e-23 82.8 1.3 3.8 3 1 1 4 4 4 3 Carbohydrate binding domain X2 DUF544 PF04424.8 KUM59805.1 - 1.9e-10 40.6 0.0 3.1e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) DUF221 PF02714.10 KUM59806.1 - 1.2e-104 349.7 21.6 1.2e-104 349.7 15.0 1.8 2 0 0 2 2 2 1 Domain of unknown function DUF221 DUF3779 PF12621.3 KUM59806.1 - 3.4e-28 97.3 0.9 7.2e-28 96.3 0.6 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KUM59806.1 - 7.7e-19 68.0 1.9 1.5e-18 67.0 1.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RSN1_TM PF13967.1 KUM59806.1 - 7.6e-05 22.3 0.1 7.6e-05 22.3 0.1 2.7 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport RRM_1 PF00076.17 KUM59806.1 - 0.11 12.1 0.0 0.32 10.6 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Gcd10p PF04189.8 KUM59807.1 - 1.2e-100 336.5 0.0 1.5e-100 336.1 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family P21-Arc PF04062.9 KUM59808.1 - 4.9e-78 260.8 0.0 5.5e-78 260.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Peptidase_M16_C PF05193.16 KUM59809.1 - 7.3e-32 110.5 0.2 4.9e-21 75.2 0.0 4.6 5 0 0 5 5 5 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KUM59809.1 - 5.8e-31 107.2 6.5 1.3e-29 102.8 1.9 3.7 2 2 1 3 3 3 1 Insulinase (Peptidase family M16) Bac_thur_toxin PF01338.13 KUM59809.1 - 0.0038 16.5 0.2 0.73 9.0 0.0 3.2 3 0 0 3 3 3 1 Bacillus thuringiensis toxin Phage_int_SAM_1 PF02899.12 KUM59809.1 - 0.0041 17.2 2.3 0.21 11.7 0.2 3.6 3 0 0 3 3 3 1 Phage integrase, N-terminal SAM-like domain Hist_deacetyl PF00850.14 KUM59810.1 - 9.2e-93 310.9 0.5 1.8e-92 309.9 0.0 1.6 2 0 0 2 2 2 1 Histone deacetylase domain Arb2 PF09757.4 KUM59810.1 - 6.4e-45 152.7 0.1 1.1e-44 151.9 0.0 1.4 1 0 0 1 1 1 1 Arb2 domain Mog1 PF04603.7 KUM59812.1 - 5.1e-13 49.1 0.0 2.3e-08 34.0 0.0 3.1 2 1 1 3 3 3 3 Ran-interacting Mog1 protein HSP9_HSP12 PF04119.7 KUM59813.1 - 6.1e-27 93.4 9.3 1.1e-26 92.6 6.4 1.5 2 0 0 2 2 2 1 Heat shock protein 9/12 AAA_13 PF13166.1 KUM59814.1 - 0.039 12.4 2.6 0.032 12.7 1.0 1.4 1 1 1 2 2 2 0 AAA domain Laminin_II PF06009.7 KUM59814.1 - 0.046 13.4 1.1 1 9.0 0.4 2.5 1 1 1 2 2 2 0 Laminin Domain II AphA_like PF14557.1 KUM59814.1 - 0.059 12.9 0.3 0.16 11.4 0.2 1.7 1 1 0 1 1 1 0 Putative AphA-like transcriptional regulator DUF3287 PF11690.3 KUM59814.1 - 0.061 13.4 2.5 2.9 7.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) DUF342 PF03961.8 KUM59814.1 - 0.22 9.9 2.9 0.33 9.3 0.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Syntaxin-6_N PF09177.6 KUM59814.1 - 0.25 11.7 6.5 18 5.8 0.0 3.5 2 1 0 3 3 3 0 Syntaxin 6, N-terminal IncA PF04156.9 KUM59814.1 - 2.6 7.5 14.9 43 3.6 10.1 2.5 1 1 0 1 1 1 0 IncA protein DivIC PF04977.10 KUM59814.1 - 7 6.2 8.3 9.2 5.8 0.7 3.4 3 0 0 3 3 3 0 Septum formation initiator TMF_DNA_bd PF12329.3 KUM59814.1 - 9.8 6.0 9.0 10 6.0 0.3 3.6 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding IBR PF01485.16 KUM59815.1 - 4.4e-22 77.7 43.1 3.1e-12 46.1 3.9 4.5 3 1 1 4 4 4 3 IBR domain zf-C3HC4_2 PF13923.1 KUM59815.1 - 1.3e-05 25.1 6.3 1.3e-05 25.1 4.3 4.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KUM59815.1 - 9.1e-05 22.2 4.4 9.1e-05 22.2 3.0 3.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 KUM59815.1 - 0.00042 19.9 3.8 0.00042 19.9 2.6 4.4 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) UN_NPL4 PF11543.3 KUM59815.1 - 0.0049 17.1 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RING_5 PF14634.1 KUM59815.1 - 0.011 15.4 6.9 0.011 15.4 4.8 4.0 2 1 1 3 3 3 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 KUM59815.1 - 0.011 15.4 1.1 0.011 15.4 0.8 3.5 3 0 0 3 3 3 0 RING-type zinc-finger NYN PF01936.13 KUM59816.1 - 0.00083 19.6 0.0 0.0044 17.3 0.0 2.1 1 1 0 1 1 1 1 NYN domain COG6 PF06419.6 KUM59817.1 - 4.2e-243 808.0 0.3 4.6e-243 807.8 0.2 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Transcrip_act PF04949.8 KUM59817.1 - 0.0016 18.1 0.4 0.0048 16.5 0.3 1.9 1 0 0 1 1 1 1 Transcriptional activator Tnp_DNA_bind PF14706.1 KUM59817.1 - 0.1 12.2 0.1 0.28 10.9 0.1 1.7 1 0 0 1 1 1 0 Transposase DNA-binding COG2 PF06148.6 KUM59817.1 - 0.11 12.3 3.9 0.096 12.5 0.7 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Shugoshin_N PF07558.6 KUM59817.1 - 0.62 9.8 2.8 0.4 10.4 0.1 2.1 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region AAA PF00004.24 KUM59818.1 - 3.4e-38 130.8 0.0 6.8e-38 129.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KUM59818.1 - 2.9e-07 30.2 0.1 4.2e-06 26.5 0.0 2.8 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 KUM59818.1 - 1.1e-05 25.5 1.7 6.4e-05 23.1 0.1 2.8 3 1 0 3 3 1 1 AAA domain AAA_2 PF07724.9 KUM59818.1 - 5.9e-05 23.0 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KUM59818.1 - 0.0001 21.4 0.0 0.00018 20.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KUM59818.1 - 0.00087 19.0 0.0 0.003 17.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KUM59818.1 - 0.0009 18.0 0.0 0.0015 17.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 KUM59818.1 - 0.0013 18.7 1.8 0.0078 16.2 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 KUM59818.1 - 0.0024 17.2 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 KUM59818.1 - 0.0029 16.7 0.1 0.0077 15.4 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KUM59818.1 - 0.0056 16.3 0.2 0.027 14.2 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 KUM59818.1 - 0.006 16.4 0.0 0.016 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KUM59818.1 - 0.013 14.9 0.2 0.13 11.6 0.1 2.4 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 KUM59818.1 - 0.016 14.8 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 KUM59818.1 - 0.022 13.7 0.0 0.036 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.1 KUM59818.1 - 0.023 15.4 0.1 0.069 13.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.1 KUM59818.1 - 0.038 13.9 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KUM59818.1 - 0.06 13.3 0.2 0.21 11.5 0.0 2.0 2 0 0 2 2 1 0 AAA domain Guanylate_kin PF00625.16 KUM59818.1 - 0.086 12.2 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 Guanylate kinase NACHT PF05729.7 KUM59818.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 KUM59818.1 - 0.12 11.8 0.0 0.34 10.3 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 KUM59818.1 - 0.16 11.1 0.0 0.33 10.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Mito_carr PF00153.22 KUM59819.1 - 4.2e-56 186.6 5.1 1.2e-21 76.2 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein W2 PF02020.13 KUM59820.1 - 8.6e-18 64.0 7.9 8.6e-18 64.0 5.4 2.5 2 1 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 KUM59820.1 - 8.4e-11 40.8 17.2 1.5e-05 24.2 0.6 4.6 2 1 3 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KUM59820.1 - 4.3e-07 29.3 14.3 0.0092 15.5 0.7 4.2 1 1 2 4 4 4 4 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.18 KUM59820.1 - 7.4e-07 28.7 0.0 1.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 KUM59820.1 - 0.0002 21.4 0.0 0.0004 20.4 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain HIN PF02760.10 KUM59820.1 - 0.14 11.5 0.1 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 HIN-200/IF120x domain DUF2666 PF10869.3 KUM59821.1 - 0.078 13.0 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) adh_short PF00106.20 KUM59822.1 - 5.5e-23 81.7 0.0 6.8e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM59822.1 - 5.2e-10 39.5 0.0 6.5e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM59822.1 - 6.4e-07 29.2 0.0 1.1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 KUM59822.1 - 7e-05 21.9 0.1 0.00011 21.3 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 KUM59822.1 - 0.0002 21.4 0.2 0.00036 20.6 0.2 1.5 1 1 1 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 KUM59822.1 - 0.0021 18.1 0.0 0.0035 17.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 KUM59822.1 - 0.0048 17.3 0.1 0.01 16.2 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Eno-Rase_NADH_b PF12242.3 KUM59822.1 - 0.022 14.5 0.1 0.062 13.0 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KUM59822.1 - 0.049 13.0 0.2 0.37 10.1 0.1 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KUM59822.1 - 0.1 11.5 0.1 0.17 10.7 0.0 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein SprT-like PF10263.4 KUM59823.1 - 1.4e-34 119.0 2.9 2.3e-34 118.3 2.0 1.3 1 0 0 1 1 1 1 SprT-like family SET PF00856.23 KUM59824.1 - 1.6e-07 31.7 0.1 4.2e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 SET domain GMC_oxred_C PF05199.8 KUM59825.1 - 2.1e-08 34.5 0.0 4.2e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Abhydrolase_6 PF12697.2 KUM59825.1 - 1.3e-06 28.5 0.0 2.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family E1-E2_ATPase PF00122.15 KUM59827.1 - 2.9e-48 163.9 0.1 6.1e-48 162.8 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.21 KUM59827.1 - 1.4e-45 153.2 0.0 5.4e-11 42.4 0.0 4.4 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.21 KUM59827.1 - 3.7e-44 151.6 0.8 8.5e-44 150.5 0.2 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KUM59827.1 - 1.5e-13 51.3 0.1 7e-13 49.1 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KUM59827.1 - 2.5e-05 23.9 0.7 0.00021 20.9 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ank_4 PF13637.1 KUM59828.1 - 1e-18 67.2 0.1 0.77 10.3 0.0 8.8 9 0 0 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM59828.1 - 1.8e-15 56.5 1.0 0.31 11.3 0.0 8.1 10 0 0 10 10 10 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 KUM59828.1 - 1.5e-14 54.0 0.0 0.053 13.8 0.0 6.7 4 3 0 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KUM59828.1 - 3.4e-09 36.0 0.0 13 5.8 0.0 7.6 8 1 0 8 8 8 3 Ankyrin repeat Ank_3 PF13606.1 KUM59828.1 - 9.1e-05 22.3 0.0 97 3.6 0.0 7.1 8 0 0 8 8 8 0 Ankyrin repeat Fungal_trans_2 PF11951.3 KUM59831.1 - 9e-06 24.5 0.7 1.4e-05 23.9 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peroxidase_2 PF01328.12 KUM59832.1 - 1.3e-21 76.6 0.1 1.6e-21 76.2 0.1 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 GMC_oxred_N PF00732.14 KUM59833.1 - 1.8e-76 257.1 0.0 2.4e-76 256.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KUM59833.1 - 1.4e-36 125.8 0.2 6.5e-36 123.7 0.1 2.0 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KUM59833.1 - 2.6e-06 26.5 0.1 0.0012 17.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KUM59833.1 - 1.5e-05 24.0 0.1 0.037 12.9 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KUM59833.1 - 0.00082 18.3 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KUM59833.1 - 0.02 14.0 0.1 0.19 10.7 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Phage_tail_S PF05069.8 KUM59833.1 - 0.15 11.7 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Phage virion morphogenesis family 2OG-FeII_Oxy_2 PF13532.1 KUM59834.1 - 4.9e-29 101.5 0.0 7e-29 101.0 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KUM59834.1 - 0.11 13.0 0.0 0.35 11.3 0.0 1.9 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.20 KUM59835.1 - 1.9e-70 236.9 0.0 2.3e-70 236.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM59835.1 - 7.4e-31 107.1 0.0 9.3e-31 106.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM59835.1 - 0.00056 18.9 0.0 0.00094 18.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KUM59835.1 - 0.0051 16.5 0.0 0.008 15.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KUM59835.1 - 0.0074 15.1 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 KUM59835.1 - 0.08 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Peptidase_C2 PF00648.16 KUM59836.1 - 6.6e-58 196.0 2.1 5.3e-37 127.4 0.2 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease WBS_methylT PF12589.3 KUM59836.1 - 0.028 14.8 4.3 0.071 13.6 3.0 1.6 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome Radial_spoke_3 PF06098.6 KUM59836.1 - 0.15 11.0 5.5 0.28 10.1 3.8 1.3 1 0 0 1 1 1 0 Radial spoke protein 3 DUF1283 PF06932.6 KUM59836.1 - 2.3 8.3 5.4 0.96 9.5 1.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1283) Fungal_trans PF04082.13 KUM59837.1 - 8.6e-24 83.8 0.0 1.4e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyoxalase PF00903.20 KUM59838.1 - 6.6e-43 145.7 0.0 5.2e-21 74.9 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KUM59838.1 - 2.1e-29 102.3 0.0 9.5e-14 51.9 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KUM59838.1 - 4.9e-20 71.5 0.0 1.4e-06 28.2 0.0 3.7 1 1 2 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KUM59838.1 - 1.3e-07 31.7 0.0 0.0018 18.1 0.0 3.5 2 1 1 3 3 3 3 Glyoxalase-like domain PRT_C PF08372.5 KUM59838.1 - 0.13 11.7 0.0 2.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Abhydrolase_3 PF07859.8 KUM59839.1 - 3e-07 30.2 0.0 1.9e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.6 KUM59839.1 - 0.00016 21.4 0.0 0.00036 20.2 0.0 1.5 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 KUM59839.1 - 0.0015 17.7 0.0 0.0027 16.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KUM59839.1 - 0.009 15.9 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KUM59839.1 - 0.03 13.7 0.0 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 Putative esterase Abhydrolase_5 PF12695.2 KUM59839.1 - 0.031 14.0 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM59839.1 - 0.097 12.2 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold MFS_1 PF07690.11 KUM59841.1 - 1.8e-36 125.5 25.5 1.8e-36 125.5 17.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Tmemb_14 PF03647.8 KUM59841.1 - 0.37 11.2 5.3 1.4 9.3 0.3 3.4 3 1 0 3 3 3 0 Transmembrane proteins 14C DUF4185 PF13810.1 KUM59842.1 - 0.098 11.5 0.0 0.11 11.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4185) DJ-1_PfpI PF01965.19 KUM59843.1 - 4.6e-20 71.5 0.0 7.5e-20 70.8 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 KUM59843.1 - 0.0056 16.1 0.0 0.017 14.6 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of DJ-1_PfpI family Glyco_trans_4_4 PF13579.1 KUM59843.1 - 0.047 13.8 0.0 0.14 12.2 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain AAA_22 PF13401.1 KUM59844.1 - 6.1e-05 23.1 0.3 0.0024 17.9 0.0 2.8 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KUM59844.1 - 0.00018 20.9 0.0 0.00042 19.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Arch_ATPase PF01637.13 KUM59844.1 - 0.00018 21.2 0.1 0.00096 18.9 0.0 2.2 3 1 1 4 4 4 1 Archaeal ATPase AAA_13 PF13166.1 KUM59844.1 - 0.0026 16.2 0.6 0.97 7.8 0.1 2.6 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.1 KUM59844.1 - 0.0035 17.2 0.0 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KUM59844.1 - 0.007 16.0 0.2 0.048 13.3 0.0 2.5 2 1 0 2 2 2 1 NACHT domain NB-ARC PF00931.17 KUM59844.1 - 0.011 14.5 0.0 0.3 9.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 KUM59844.1 - 0.013 15.6 0.0 0.037 14.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 KUM59844.1 - 0.023 14.2 0.0 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KUM59844.1 - 0.033 14.3 0.0 0.096 12.8 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KUM59844.1 - 0.036 14.0 0.0 0.48 10.3 0.0 2.5 1 1 1 2 2 2 0 AAA ATPase domain Allexi_40kDa PF05549.6 KUM59844.1 - 0.043 13.1 0.2 0.043 13.1 0.1 2.8 3 1 1 4 4 4 0 Allexivirus 40kDa protein Zeta_toxin PF06414.7 KUM59844.1 - 0.08 12.0 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin KaiC PF06745.8 KUM59844.1 - 0.1 11.7 0.0 0.28 10.2 0.0 1.7 1 0 0 1 1 1 0 KaiC Amidase PF01425.16 KUM59846.1 - 2.8e-74 250.5 0.0 3.5e-74 250.2 0.0 1.0 1 0 0 1 1 1 1 Amidase Big_4 PF07532.6 KUM59846.1 - 0.067 12.7 0.5 0.18 11.3 0.3 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 4) ABC2_membrane PF01061.19 KUM59848.1 - 5.6e-77 257.6 58.0 2.1e-41 141.4 16.0 4.1 4 1 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 KUM59848.1 - 3.8e-37 127.6 0.0 9.2e-18 64.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KUM59848.1 - 3e-35 119.9 0.7 5.5e-28 96.6 0.0 2.6 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 KUM59848.1 - 2.3e-10 40.0 31.3 4.1e-05 22.7 8.3 2.9 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.1 KUM59848.1 - 5.7e-08 32.9 0.3 1.2e-06 28.6 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain ABC_trans_N PF14510.1 KUM59848.1 - 1.6e-07 31.3 0.0 6.5e-07 29.3 0.0 2.1 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_21 PF13304.1 KUM59848.1 - 2.5e-07 30.9 0.1 0.0072 16.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KUM59848.1 - 2.6e-07 30.2 0.1 0.00053 19.4 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KUM59848.1 - 1.7e-06 28.8 0.0 0.0012 19.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KUM59848.1 - 8.8e-06 25.1 0.1 0.0017 17.8 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KUM59848.1 - 1.7e-05 24.9 0.1 0.023 14.8 0.0 3.3 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 KUM59848.1 - 6.2e-05 22.2 0.0 0.00029 20.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 KUM59848.1 - 0.00015 21.2 0.0 0.0064 15.9 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 KUM59848.1 - 0.00018 21.0 0.2 0.41 10.0 0.0 2.7 3 0 0 3 3 2 2 FtsK/SpoIIIE family AAA_18 PF13238.1 KUM59848.1 - 0.00034 20.9 0.0 0.024 14.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KUM59848.1 - 0.00046 20.0 0.0 0.075 12.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KUM59848.1 - 0.0009 19.2 0.5 0.0025 17.7 0.1 2.0 2 0 0 2 2 1 1 AAA domain AAA_10 PF12846.2 KUM59848.1 - 0.0015 18.0 0.1 0.91 8.9 0.1 2.5 2 0 0 2 2 2 2 AAA-like domain NACHT PF05729.7 KUM59848.1 - 0.0017 18.0 0.0 0.03 13.9 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 KUM59848.1 - 0.0036 17.0 0.1 0.23 11.2 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain ABC_ATPase PF09818.4 KUM59848.1 - 0.0037 15.9 0.1 0.71 8.3 0.1 2.4 2 0 0 2 2 2 1 Predicted ATPase of the ABC class T2SE PF00437.15 KUM59848.1 - 0.013 14.3 0.2 0.14 11.0 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein MMR_HSR1 PF01926.18 KUM59848.1 - 0.017 15.0 0.7 0.7 9.8 0.2 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.1 KUM59848.1 - 0.018 14.6 0.1 0.11 12.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KUM59848.1 - 0.02 14.5 0.4 0.16 11.5 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SMC_N PF02463.14 KUM59848.1 - 0.033 13.4 0.1 4.5 6.4 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.17 KUM59848.1 - 0.059 13.5 0.1 2.9 8.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 KUM59848.1 - 0.059 13.5 0.0 0.82 9.8 0.0 2.7 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 KUM59848.1 - 0.06 13.6 0.9 0.11 12.8 0.1 1.8 2 0 0 2 2 1 0 AAA domain Arch_ATPase PF01637.13 KUM59848.1 - 0.17 11.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase PduV-EutP PF10662.4 KUM59848.1 - 0.3 10.5 1.3 0.83 9.1 0.0 2.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation PsbH PF00737.15 KUM59849.1 - 0.051 13.1 0.1 0.093 12.3 0.0 1.5 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein adh_short PF00106.20 KUM59850.1 - 4.3e-16 59.2 0.0 5.7e-15 55.6 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KUM59850.1 - 6.1e-09 35.7 0.0 1.4e-08 34.6 0.0 1.5 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KUM59850.1 - 5.6e-05 23.2 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KUM59850.1 - 0.00072 19.0 0.0 0.0014 18.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KUM59850.1 - 0.0019 17.9 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 KUM59850.1 - 0.018 14.2 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family E1-N PF14463.1 KUM59850.1 - 0.046 13.3 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 E1 N-terminal domain Glyco_trans_4_4 PF13579.1 KUM59850.1 - 0.084 13.0 0.1 0.18 11.9 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain RmlD_sub_bind PF04321.12 KUM59850.1 - 0.096 11.5 1.3 0.13 11.1 0.0 1.8 3 0 0 3 3 3 0 RmlD substrate binding domain CT47 PF15623.1 KUM59850.1 - 3.7 7.2 10.2 4.9 6.8 7.1 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 G-patch PF01585.18 KUM59851.1 - 0.0011 18.7 0.2 0.0024 17.6 0.2 1.6 1 0 0 1 1 1 1 G-patch domain DUF605 PF04652.11 KUM59851.1 - 5.6 6.2 8.7 7 5.9 6.0 1.2 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 KUM59852.1 - 6.8e-279 927.5 3.0 7.7e-279 927.4 2.1 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Epimerase PF01370.16 KUM59853.1 - 5.5e-46 156.9 0.0 7.7e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 KUM59853.1 - 3.9e-25 87.5 0.2 6.8e-25 86.7 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 KUM59853.1 - 2e-15 56.2 0.0 2.8e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KUM59853.1 - 6.6e-12 44.9 0.0 1.3e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KUM59853.1 - 9.1e-12 44.4 0.0 6.7e-10 38.3 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KUM59853.1 - 1.6e-08 34.6 0.0 3.1e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KUM59853.1 - 1.2e-07 31.9 0.0 1.9e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KUM59853.1 - 1.1e-06 27.8 0.0 4.8e-06 25.6 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 KUM59853.1 - 2.9e-06 27.0 0.0 5.4e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KUM59853.1 - 0.0017 18.1 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 KUM59853.1 - 0.017 14.3 0.0 0.057 12.6 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family UDPG_MGDP_dh_N PF03721.9 KUM59853.1 - 0.038 13.3 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Cys_Met_Meta_PP PF01053.15 KUM59853.1 - 0.078 11.2 0.1 0.42 8.8 0.0 2.0 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Phage_lysozyme PF00959.14 KUM59853.1 - 0.13 12.5 0.1 0.8 10.0 0.0 2.1 2 0 0 2 2 2 0 Phage lysozyme Methyltransf_18 PF12847.2 KUM59854.1 - 2.2e-10 41.1 0.0 4.4e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM59854.1 - 2.2e-07 30.5 0.1 4.4e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM59854.1 - 1.6e-05 24.6 0.0 2.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 KUM59854.1 - 0.00014 22.6 0.0 0.0004 21.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.12 KUM59854.1 - 0.00038 19.5 0.0 0.00057 18.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_11 PF08241.7 KUM59854.1 - 0.00042 20.7 0.0 0.00092 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM59854.1 - 0.00097 19.4 0.0 0.0029 17.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KUM59854.1 - 0.0017 17.9 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 KUM59854.1 - 0.032 14.2 0.0 0.046 13.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 KUM59854.1 - 0.035 13.2 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KUM59854.1 - 0.14 12.6 0.2 0.35 11.3 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 KUM59854.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain IceA2 PF05862.6 KUM59855.1 - 0.0037 16.9 2.6 2.4 7.9 0.1 3.7 1 1 2 3 3 3 3 Helicobacter pylori IceA2 protein DUF4358 PF14270.1 KUM59855.1 - 0.029 14.2 1.3 13 5.6 0.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4358) DUF4520 PF15016.1 KUM59855.1 - 0.049 13.2 1.5 16 5.1 0.2 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4520) Peptidase_M10_C PF08548.6 KUM59855.1 - 0.17 11.4 0.5 0.78 9.2 0.3 2.3 1 1 0 1 1 1 0 Peptidase M10 serralysin C terminal NifT PF06988.6 KUM59855.1 - 0.32 10.4 10.3 12 5.3 0.6 3.6 1 1 3 4 4 4 0 NifT/FixU protein GRASP55_65 PF04495.9 KUM59855.1 - 0.42 10.5 12.0 1.7e+02 2.1 0.0 5.5 1 1 1 2 2 2 0 GRASP55/65 PDZ-like domain DpnII PF04556.7 KUM59855.1 - 3.6 6.5 6.8 12 4.9 0.2 3.5 1 1 2 3 3 3 0 DpnII restriction endonuclease Npa1 PF11707.3 KUM59857.1 - 1.3e-99 333.3 0.0 3.6e-99 331.8 0.0 1.8 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal PqqD PF05402.7 KUM59857.1 - 0.048 13.6 0.2 0.33 11.0 0.0 2.6 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) Acetyltransf_1 PF00583.19 KUM59858.1 - 3.9e-09 36.4 0.0 2.1e-08 34.0 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KUM59858.1 - 2.7e-06 27.4 0.0 8.8e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KUM59858.1 - 3.2e-05 24.0 0.0 8e-05 22.7 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KUM59858.1 - 0.00025 20.7 0.0 0.00041 20.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Arfaptin PF06456.8 KUM59859.1 - 0.047 13.0 1.2 0.055 12.8 0.9 1.1 1 0 0 1 1 1 0 Arfaptin-like domain DUF651 PF04895.7 KUM59859.1 - 0.46 10.1 2.0 0.6 9.7 0.9 1.6 1 1 0 1 1 1 0 Archaeal protein of unknown function (DUF651) HA2 PF04408.18 KUM59860.1 - 1.4e-28 98.9 0.1 1.4e-28 98.9 0.1 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KUM59860.1 - 6.4e-26 90.4 0.0 4.7e-25 87.6 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KUM59860.1 - 6.6e-12 45.1 0.0 1.5e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 KUM59860.1 - 1.6e-10 40.9 0.7 3.1e-10 39.9 0.5 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 KUM59860.1 - 2.7e-05 23.7 0.0 5.8e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 KUM59860.1 - 0.00016 20.6 0.0 0.00039 19.4 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 KUM59860.1 - 0.00051 20.1 0.0 0.0015 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KUM59860.1 - 0.067 12.3 0.1 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.1 KUM59860.1 - 0.072 12.6 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 KUM59860.1 - 0.075 12.7 0.1 0.2 11.3 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain G_glu_transpept PF01019.16 KUM59861.1 - 2.6e-135 451.8 0.0 3e-135 451.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase MFS_1 PF07690.11 KUM59862.1 - 2.4e-18 65.9 45.9 1.7e-16 59.9 9.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1110 PF06533.7 KUM59862.1 - 0.04 13.7 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1110) ABC_tran PF00005.22 KUM59863.1 - 8.2e-46 155.7 0.0 7.5e-29 100.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KUM59863.1 - 5e-32 111.4 21.0 2e-19 70.0 6.4 3.5 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 KUM59863.1 - 4.8e-14 52.1 0.0 2.5e-06 26.8 0.0 4.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KUM59863.1 - 3.9e-09 36.8 0.0 0.0069 16.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 KUM59863.1 - 3.8e-05 24.0 0.0 0.14 12.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KUM59863.1 - 7.6e-05 22.1 0.0 0.16 11.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 KUM59863.1 - 0.00026 20.9 1.3 0.052 13.3 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_16 PF13191.1 KUM59863.1 - 0.00066 19.7 1.3 0.11 12.4 0.1 3.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KUM59863.1 - 0.00081 18.8 0.5 1.3 8.6 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KUM59863.1 - 0.0011 19.1 0.1 3.8 7.6 0.0 3.3 2 1 0 2 2 2 2 AAA domain T2SE PF00437.15 KUM59863.1 - 0.0021 16.9 0.0 0.53 9.1 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.24 KUM59863.1 - 0.0048 17.0 0.1 0.81 9.8 0.0 3.4 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 KUM59863.1 - 0.005 16.7 0.1 0.26 11.2 0.0 2.8 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 KUM59863.1 - 0.0063 15.9 0.9 5.3 6.3 0.1 3.0 2 1 1 3 3 3 0 AAA-like domain DUF2075 PF09848.4 KUM59863.1 - 0.008 15.1 0.1 1.1 8.1 0.0 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) DUF258 PF03193.11 KUM59863.1 - 0.0084 15.3 0.1 1.5 8.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KUM59863.1 - 0.0087 16.8 0.0 0.43 11.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KUM59863.1 - 0.032 13.6 0.6 1.7 8.0 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 KUM59863.1 - 0.037 13.5 0.0 2.5 7.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family SbcCD_C PF13558.1 KUM59863.1 - 0.047 13.6 0.0 5.7 6.9 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 KUM59863.1 - 0.053 13.0 0.0 14 5.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KUM59863.1 - 0.061 13.5 0.1 19 5.4 0.0 2.9 3 0 0 3 3 2 0 RNA helicase Pox_A32 PF04665.7 KUM59863.1 - 0.071 12.3 0.1 1 8.6 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein Miro PF08477.8 KUM59863.1 - 0.077 13.4 0.0 2.8 8.4 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein NB-ARC PF00931.17 KUM59863.1 - 0.086 11.6 0.1 9.3 5.0 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain Zeta_toxin PF06414.7 KUM59863.1 - 0.18 10.8 0.1 2.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.1 KUM59863.1 - 0.3 11.3 0.0 3.8 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KUM59863.1 - 1.1 8.8 4.7 6.1 6.4 0.1 3.4 4 0 0 4 4 3 0 NACHT domain adh_short PF00106.20 KUM59864.1 - 7.2e-31 107.3 0.0 9.1e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM59864.1 - 2.1e-23 83.3 0.0 2.5e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM59864.1 - 8.4e-14 51.6 0.0 1.1e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KUM59864.1 - 0.0089 15.7 0.2 0.019 14.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SUV3_C PF12513.3 KUM59865.1 - 1.4e-16 59.6 0.1 4.1e-16 58.1 0.1 1.9 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 KUM59865.1 - 2e-09 37.1 0.0 4.4e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Sec1 PF00995.18 KUM59866.1 - 4.5e-140 467.9 0.0 5.5e-140 467.6 0.0 1.1 1 0 0 1 1 1 1 Sec1 family SR-25 PF10500.4 KUM59866.1 - 0.3 10.5 9.1 0.57 9.6 6.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Dus PF01207.12 KUM59867.1 - 1.6e-58 197.9 0.0 2.3e-58 197.4 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 KUM59867.1 - 0.0014 17.6 0.0 0.0023 16.9 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase WD40 PF00400.27 KUM59868.1 - 1.4e-05 24.7 0.9 0.73 9.8 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat Proteasome_A_N PF10584.4 KUM59868.1 - 0.019 14.2 0.4 1.2 8.5 0.0 3.3 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature PD40 PF07676.7 KUM59868.1 - 0.025 14.2 0.2 2.2 8.0 0.2 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat eIF2A PF08662.6 KUM59868.1 - 0.12 12.0 0.3 5.5 6.6 0.0 3.0 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A NOGCT PF08155.6 KUM59869.1 - 9e-28 95.7 3.6 1.9e-27 94.7 2.5 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 KUM59869.1 - 2.7e-26 91.2 0.4 6.3e-26 90.0 0.3 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 KUM59869.1 - 5.7e-15 55.2 0.0 1.2e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KUM59869.1 - 4.4e-07 29.3 0.0 1.3e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KUM59869.1 - 0.0012 19.3 0.0 0.005 17.3 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 KUM59869.1 - 0.0082 15.9 0.0 5.2 6.8 0.0 2.6 1 1 1 2 2 2 2 Dynamin family Sugar_tr PF00083.19 KUM59870.1 - 9.2e-133 443.1 31.0 2.8e-132 441.5 21.5 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM59870.1 - 1.4e-24 86.4 49.4 1.7e-20 73.0 19.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.4 KUM59870.1 - 0.0031 17.4 1.0 0.017 15.1 0.7 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2530) NAD_binding_2 PF03446.10 KUM59871.1 - 3.8e-22 78.8 0.0 5.8e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KUM59871.1 - 8.4e-08 32.3 0.2 2.5e-07 30.7 0.1 1.8 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KUM59871.1 - 0.027 14.9 0.0 0.061 13.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KUM59871.1 - 0.03 14.4 0.0 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1068 PF06364.7 KUM59871.1 - 0.11 12.0 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) DSBA PF01323.15 KUM59872.1 - 2.1e-11 43.7 0.0 2.3e-11 43.5 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Sugar_tr PF00083.19 KUM59873.1 - 4.8e-81 272.6 28.9 5.4e-81 272.4 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM59873.1 - 2.5e-19 69.2 21.2 1.3e-18 66.9 8.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KUM59873.1 - 1.4 9.0 9.4 0.25 11.3 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) DPM3 PF08285.6 KUM59874.1 - 0.05 13.4 0.1 0.15 11.9 0.0 1.9 1 1 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF619 PF04768.8 KUM59875.1 - 2.8e-53 179.8 0.0 5.7e-52 175.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Acetyltransf_1 PF00583.19 KUM59876.1 - 3.1e-12 46.3 0.0 4.8e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KUM59876.1 - 6.5e-09 35.8 0.0 1.1e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KUM59876.1 - 0.00021 21.1 0.0 0.00044 20.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KUM59876.1 - 0.00059 19.7 0.1 0.0016 18.3 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KUM59876.1 - 0.0013 18.7 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KUM59876.1 - 0.0099 15.7 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 KUM59876.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein MFS_1 PF07690.11 KUM59878.1 - 2.2e-42 145.0 52.6 3.8e-42 144.2 33.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM59878.1 - 9.1e-05 21.2 30.0 0.00064 18.4 20.8 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter Cofilin_ADF PF00241.15 KUM59878.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein Erg28 PF03694.8 KUM59879.1 - 1.4e-36 124.8 0.2 1.7e-36 124.6 0.1 1.1 1 0 0 1 1 1 1 Erg28 like protein GalP_UDP_transf PF01087.17 KUM59880.1 - 7.9e-69 231.3 0.4 6.2e-67 225.2 0.2 2.4 2 1 1 3 3 3 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 KUM59880.1 - 2.4e-55 186.6 0.3 5.1e-55 185.5 0.1 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 KUM59880.1 - 0.019 15.4 0.0 0.087 13.3 0.0 2.0 2 1 0 2 2 2 0 HIT domain Flavoprotein PF02441.14 KUM59881.1 - 1.3e-42 144.4 0.3 2.4e-42 143.6 0.2 1.4 1 0 0 1 1 1 1 Flavoprotein adh_short PF00106.20 KUM59882.1 - 4e-20 72.3 0.1 6.4e-20 71.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM59882.1 - 2.1e-08 34.2 0.0 3.1e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM59882.1 - 5.5e-05 22.9 0.1 9.8e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KUM59882.1 - 0.022 14.7 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 KUM59882.1 - 0.15 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DMA PF03474.9 KUM59883.1 - 0.083 12.7 0.2 0.23 11.3 0.2 1.8 1 0 0 1 1 1 0 DMRTA motif HSP70 PF00012.15 KUM59884.1 - 2.6e-09 35.5 0.0 3.2e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KUM59884.1 - 7.2e-06 24.8 0.2 6.9e-05 21.5 0.1 2.0 1 1 0 1 1 1 1 MreB/Mbl protein Actin PF00022.14 KUM59884.1 - 0.054 11.9 0.0 0.11 10.8 0.0 1.5 1 0 0 1 1 1 0 Actin Ribosomal_L7Ae PF01248.21 KUM59885.1 - 3.3e-24 84.2 0.0 4e-24 83.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KUM59885.1 - 2.9e-05 23.9 0.0 3e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 DUF3533 PF12051.3 KUM59887.1 - 7.7e-98 327.7 15.9 8.7e-98 327.5 11.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Trp_halogenase PF04820.9 KUM59888.1 - 4.6e-07 28.8 0.1 0.00093 17.9 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase DAO PF01266.19 KUM59888.1 - 2.7e-05 23.2 1.2 4.9e-05 22.3 0.3 1.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KUM59888.1 - 6.2e-05 22.2 0.1 0.029 13.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KUM59888.1 - 6.2e-05 22.9 0.1 0.00017 21.5 0.1 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KUM59888.1 - 0.00012 21.1 0.0 0.00048 19.0 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KUM59888.1 - 0.00028 20.8 0.0 0.00038 20.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KUM59888.1 - 0.0037 15.7 0.1 0.0057 15.1 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 KUM59888.1 - 0.0083 16.5 0.3 0.017 15.5 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KUM59888.1 - 0.029 13.2 0.0 0.045 12.6 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KUM59888.1 - 0.037 12.9 0.6 0.23 10.3 0.4 1.9 1 1 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 KUM59888.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.2 KUM59888.1 - 0.17 10.9 0.2 0.26 10.3 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase PhyH PF05721.8 KUM59889.1 - 1.7e-08 34.7 0.3 4.2e-08 33.4 0.2 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 KUM59889.1 - 1.5e-07 30.2 0.0 0.15 10.5 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) PTR2 PF00854.16 KUM59890.1 - 4.1e-09 35.6 0.1 7.7e-09 34.8 0.0 1.4 2 0 0 2 2 2 1 POT family MFS_1 PF07690.11 KUM59890.1 - 0.002 16.8 1.2 0.0023 16.6 0.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 KUM59891.1 - 1.8e-08 33.5 0.7 2.9e-08 32.9 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PhyH PF05721.8 KUM59892.1 - 1e-06 28.9 0.0 3.4e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 KUM59892.1 - 5.4e-06 25.1 0.2 0.095 11.1 0.0 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF1479) Fungal_trans PF04082.13 KUM59893.1 - 8.5e-17 60.8 0.4 2.6e-16 59.2 0.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM59893.1 - 5.1e-09 35.9 14.0 8.5e-09 35.1 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S15 PF02129.13 KUM59894.1 - 4.7e-41 140.9 0.5 2.5e-39 135.3 0.0 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 KUM59894.1 - 3e-26 92.6 0.0 4.5e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 KUM59894.1 - 2.6e-06 27.4 0.0 3.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM59894.1 - 0.00037 20.2 0.0 0.00065 19.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KUM59894.1 - 0.038 13.8 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Peptidase_S9 PF00326.16 KUM59894.1 - 0.1 11.8 0.3 0.25 10.5 0.2 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Fungal_trans PF04082.13 KUM59895.1 - 3.1e-06 26.2 0.3 6.2e-06 25.2 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM59895.1 - 1e-05 25.3 11.2 1.7e-05 24.6 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prefoldin PF02996.12 KUM59896.1 - 5e-20 71.3 0.6 3.1e-19 68.7 0.4 1.9 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 KUM59896.1 - 0.0026 17.4 0.3 0.11 12.2 0.1 2.1 2 0 0 2 2 2 1 Prefoldin subunit DASH_Hsk3 PF08227.6 KUM59896.1 - 0.11 12.6 0.3 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like KH_1 PF00013.24 KUM59897.1 - 0.12 12.0 0.0 0.41 10.3 0.0 1.9 2 0 0 2 2 2 0 KH domain AAA PF00004.24 KUM59898.1 - 7.4e-14 52.0 0.0 1.4e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KUM59898.1 - 1.7e-09 37.9 0.0 5.2e-09 36.3 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KUM59898.1 - 7.7e-08 32.5 0.0 2.3e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain BAH PF01426.13 KUM59898.1 - 6.2e-06 25.9 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 BAH domain AAA_17 PF13207.1 KUM59898.1 - 2.7e-05 24.9 0.0 0.00081 20.1 0.0 3.3 4 0 0 4 4 3 1 AAA domain AAA_19 PF13245.1 KUM59898.1 - 0.0013 18.3 0.9 0.0045 16.7 0.1 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 KUM59898.1 - 0.0025 17.8 0.0 0.007 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KUM59898.1 - 0.0071 16.6 0.7 0.023 15.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.4 KUM59898.1 - 0.0079 15.2 0.0 0.016 14.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 KUM59898.1 - 0.008 15.8 0.0 0.019 14.6 0.0 1.6 1 1 0 1 1 1 1 NACHT domain AAA_11 PF13086.1 KUM59898.1 - 0.016 14.7 0.0 0.048 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_32 PF13654.1 KUM59898.1 - 0.023 13.3 0.0 0.038 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.9 KUM59898.1 - 0.038 12.9 0.0 0.077 11.9 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase AAA_33 PF13671.1 KUM59898.1 - 0.044 13.6 0.0 0.3 10.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KUM59898.1 - 0.079 12.6 0.0 0.79 9.3 0.0 2.2 1 1 0 1 1 1 0 Archaeal ATPase Kinesin PF00225.18 KUM59898.1 - 0.096 11.3 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 Kinesin motor domain RNA_helicase PF00910.17 KUM59898.1 - 0.13 12.4 0.1 0.42 10.8 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Zot PF05707.7 KUM59898.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) NB-ARC PF00931.17 KUM59898.1 - 0.17 10.6 0.0 0.55 9.0 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain WD40 PF00400.27 KUM59899.1 - 9.9e-56 183.7 12.1 1.6e-09 37.2 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KUM59899.1 - 0.0078 14.4 5.5 10 4.1 0.0 4.6 1 1 2 4 4 4 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KUM59899.1 - 0.038 13.4 0.1 2.1 7.7 0.0 2.5 2 0 0 2 2 2 0 PQQ-like domain Ank_2 PF12796.2 KUM59900.1 - 1.1e-40 137.8 0.1 2e-18 66.4 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KUM59900.1 - 2.5e-36 122.8 0.1 3e-10 39.9 0.0 4.7 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 KUM59900.1 - 1.7e-32 109.5 0.1 5.2e-05 22.8 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 KUM59900.1 - 1.6e-30 104.8 0.1 8.9e-10 38.8 0.0 4.7 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM59900.1 - 1.2e-26 90.0 0.1 0.0021 18.1 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Shal-type PF11601.3 KUM59900.1 - 0.039 13.4 0.2 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 Shal-type voltage-gated potassium channels LHH PF14411.1 KUM59900.1 - 0.04 14.1 0.0 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH Pyr_redox_3 PF13738.1 KUM59901.1 - 6.6e-28 98.1 0.0 1.3e-27 97.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KUM59901.1 - 4.9e-21 74.5 0.3 1.9e-19 69.2 0.0 2.8 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KUM59901.1 - 4.5e-11 42.2 0.1 1.6e-06 27.2 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KUM59901.1 - 1.6e-08 34.6 0.0 8.3e-08 32.3 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM59901.1 - 1.6e-07 31.2 0.0 3.7e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KUM59901.1 - 5.9e-06 26.6 0.0 0.17 12.2 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KUM59901.1 - 6.5e-06 25.2 0.0 0.00012 21.0 0.0 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KUM59901.1 - 0.00018 21.2 0.1 0.0017 18.1 0.0 2.6 4 0 0 4 4 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 KUM59901.1 - 0.00042 19.4 0.0 0.0012 17.9 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Shikimate_DH PF01488.15 KUM59901.1 - 0.00055 20.0 0.1 1.6 8.7 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 KUM59901.1 - 0.0081 15.0 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 KUM59901.1 - 0.032 14.4 0.0 1.5 9.1 0.0 2.7 3 0 0 3 3 3 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 KUM59901.1 - 0.032 13.3 0.0 0.21 10.7 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KUM59901.1 - 0.056 12.3 0.2 0.35 9.7 0.0 2.4 2 1 0 2 2 2 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 KUM59901.1 - 0.066 12.9 0.1 9.4 5.9 0.0 2.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.9 KUM59901.1 - 0.12 10.8 0.2 0.2 10.0 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein MFS_1 PF07690.11 KUM59902.1 - 8e-25 87.2 37.2 8e-25 87.2 25.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MMPL PF03176.10 KUM59902.1 - 0.061 12.0 1.0 0.73 8.4 0.1 2.4 2 0 0 2 2 2 0 MMPL family DUF2207 PF09972.4 KUM59902.1 - 3.2 6.2 8.5 0.61 8.6 0.8 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Sugar_tr PF00083.19 KUM59905.1 - 2.5e-11 42.8 8.0 2.5e-11 42.8 5.6 2.3 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM59905.1 - 9.4e-11 41.0 46.1 4.4e-07 28.9 13.0 3.4 2 2 2 4 4 4 3 Major Facilitator Superfamily DUF3794 PF12673.2 KUM59905.1 - 0.07 13.2 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3794) Fungal_trans PF04082.13 KUM59906.1 - 3.3e-10 39.2 0.8 5.5e-10 38.5 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KUM59907.1 - 7.2e-42 143.3 46.6 7.2e-42 143.3 32.3 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM59907.1 - 6.7e-18 64.2 15.2 6.7e-18 64.2 10.5 2.6 1 1 2 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KUM59907.1 - 4e-12 45.4 14.6 4e-12 45.4 10.1 3.4 4 0 0 4 4 4 1 Sugar (and other) transporter ATG22 PF11700.3 KUM59907.1 - 2.2e-07 29.7 12.4 2.2e-07 29.7 8.6 2.6 4 0 0 4 4 4 1 Vacuole effluxer Atg22 like CENP-F_leu_zip PF10473.4 KUM59908.1 - 0.05 13.4 20.4 0.034 13.9 11.1 2.6 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 KUM59908.1 - 0.061 12.4 0.7 0.2 10.8 0.1 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF4599 PF15371.1 KUM59908.1 - 0.076 13.0 0.4 0.076 13.0 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4599) Porph_ging PF09697.5 KUM59908.1 - 0.34 11.0 2.1 7.2 6.8 1.5 2.9 1 1 0 1 1 1 0 Protein of unknown function (Porph_ging) Mannitol_dh PF01232.18 KUM59908.1 - 0.4 10.6 4.7 2.5 8.0 0.2 2.5 1 1 1 2 2 2 0 Mannitol dehydrogenase Rossmann domain V_ATPase_I PF01496.14 KUM59908.1 - 0.6 7.8 8.6 0.72 7.6 5.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3450 PF11932.3 KUM59908.1 - 0.72 9.0 12.6 0.24 10.6 2.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.7 KUM59908.1 - 2 8.1 15.0 2.1 8.0 0.2 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF367 PF04034.8 KUM59909.1 - 4.1e-48 162.1 0.1 6.4e-48 161.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 KUM59909.1 - 1.9e-11 43.3 1.0 4.3e-11 42.2 0.7 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Nop53 PF07767.6 KUM59909.1 - 0.058 12.3 11.1 0.085 11.8 7.7 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Lin-8 PF03353.10 KUM59909.1 - 0.35 10.0 12.0 0.49 9.6 8.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Cwf_Cwc_15 PF04889.7 KUM59909.1 - 0.6 9.7 19.8 0.93 9.1 13.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.7 KUM59909.1 - 1.7 7.8 23.6 2.4 7.3 16.4 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 KUM59909.1 - 2 6.2 27.1 2.6 5.8 18.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KUM59909.1 - 3.9 5.3 16.2 5.2 4.9 11.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Ebola_NP PF05505.7 KUM59909.1 - 6.6 4.6 10.8 8 4.3 7.5 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Daxx PF03344.10 KUM59909.1 - 7.9 4.8 23.8 11 4.4 16.5 1.1 1 0 0 1 1 1 0 Daxx Family VHS PF00790.14 KUM59910.1 - 2.1e-44 150.5 0.0 8.3e-44 148.6 0.0 2.0 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 KUM59910.1 - 8.2e-25 86.7 0.6 2.6e-24 85.0 0.4 1.9 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 KUM59910.1 - 1.7e-22 79.8 0.6 4.3e-22 78.6 0.4 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain BLVR PF06375.6 KUM59911.1 - 0.01 15.6 7.2 0.01 15.6 5.0 1.0 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) MIT PF04212.13 KUM59911.1 - 0.011 15.6 0.1 0.013 15.3 0.1 1.2 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain ATP-synt_E PF05680.7 KUM59911.1 - 0.044 13.7 2.4 0.047 13.6 1.7 1.1 1 0 0 1 1 1 0 ATP synthase E chain OPA3 PF07047.7 KUM59911.1 - 0.36 10.6 4.4 0.41 10.4 3.1 1.1 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) TSGP1 PF07771.6 KUM59911.1 - 0.64 9.9 4.4 0.61 9.9 3.1 1.1 1 0 0 1 1 1 0 Tick salivary peptide group 1 Peptidase_S49_N PF08496.5 KUM59911.1 - 1.2 8.9 6.1 1.3 8.7 4.2 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal UPF0542 PF15086.1 KUM59911.1 - 7.7 6.3 9.3 10 5.8 6.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 CBS PF00571.23 KUM59913.1 - 2.3e-19 68.9 3.2 3.4e-06 26.7 0.1 5.3 5 0 0 5 5 5 4 CBS domain Epimerase PF01370.16 KUM59914.1 - 2.6e-14 53.2 0.0 6.2e-14 52.0 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KUM59914.1 - 3.2e-12 45.7 0.0 4.3e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KUM59914.1 - 1.2e-09 38.4 0.0 2.1e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KUM59914.1 - 2.2e-07 30.0 0.5 0.00087 18.2 0.0 2.5 3 0 0 3 3 3 2 Male sterility protein NmrA PF05368.8 KUM59914.1 - 5.1e-05 22.6 0.0 7.7e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KUM59914.1 - 0.0011 18.8 0.0 0.0029 17.5 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KUM59914.1 - 0.0055 15.6 0.0 0.0091 14.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 KUM59914.1 - 0.088 12.4 1.0 0.69 9.5 0.7 2.1 1 1 0 1 1 1 0 KR domain CTP_transf_1 PF01148.15 KUM59915.1 - 4e-07 29.9 16.9 0.00017 21.3 0.3 3.1 3 0 0 3 3 3 2 Cytidylyltransferase family DUF3543 PF12063.3 KUM59916.1 - 1.9e-91 305.5 0.0 3.9e-91 304.5 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 KUM59916.1 - 9e-62 208.5 0.0 1.6e-61 207.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM59916.1 - 1.8e-42 145.1 0.0 3.1e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM59916.1 - 0.02 13.8 0.0 0.3 9.9 0.0 2.2 2 0 0 2 2 2 0 Kinase-like zf-C2H2 PF00096.21 KUM59917.1 - 3.8e-12 45.7 12.1 2.3e-06 27.5 0.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KUM59917.1 - 5.3e-10 38.9 10.7 0.00026 21.1 3.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KUM59917.1 - 1.6e-07 31.2 11.1 2.8e-06 27.3 3.0 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 KUM59917.1 - 8.2e-05 22.6 4.9 0.0032 17.6 0.3 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KUM59917.1 - 0.00038 20.4 10.6 0.0023 18.0 0.6 2.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KUM59917.1 - 0.018 14.9 9.4 0.021 14.7 0.2 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KUM59917.1 - 0.44 10.6 3.8 5.8 7.0 0.3 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 KUM59917.1 - 3.5 7.4 7.2 1.4 8.7 1.5 2.2 1 1 1 2 2 2 0 BED zinc finger zf-C2HC_2 PF13913.1 KUM59917.1 - 9.7 5.9 7.4 13 5.5 1.4 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type ATP_bind_4 PF01902.12 KUM59918.1 - 2.6e-17 62.9 0.0 4.5e-11 42.5 0.0 3.3 2 1 0 2 2 2 2 ATP-binding region Ribonuc_L-PSP PF01042.16 KUM59918.1 - 3.4e-16 59.1 0.1 6.8e-08 32.2 0.0 3.4 3 0 0 3 3 3 2 Endoribonuclease L-PSP DEAD PF00270.24 KUM59919.1 - 7e-41 139.5 0.0 3.5e-40 137.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM59919.1 - 2.9e-25 87.9 0.4 6.9e-25 86.7 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF2986 PF11661.3 KUM59919.1 - 0.013 15.7 4.0 0.051 13.9 2.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2986) DUF3334 PF11813.3 KUM59919.1 - 0.031 13.8 0.0 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) ResIII PF04851.10 KUM59919.1 - 0.055 13.2 0.0 0.16 11.8 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Suf PF05843.9 KUM59920.1 - 0.0028 17.4 1.9 0.03 14.0 0.1 2.8 2 1 1 3 3 3 1 Suppressor of forked protein (Suf) FAT PF02259.18 KUM59920.1 - 0.022 13.7 1.2 0.14 11.0 0.1 2.8 3 2 1 4 4 4 0 FAT domain HAT PF02184.11 KUM59920.1 - 0.79 9.5 19.0 1.9 8.2 0.2 6.2 6 0 0 6 6 6 0 HAT (Half-A-TPR) repeat AA_permease_2 PF13520.1 KUM59921.1 - 1.1e-95 320.6 40.5 1.4e-95 320.3 28.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM59921.1 - 1.8e-23 82.6 36.2 2.7e-23 82.0 25.1 1.2 1 0 0 1 1 1 1 Amino acid permease Peptidase_M1 PF01433.15 KUM59922.1 - 2.6e-143 477.8 0.8 3.2e-143 477.5 0.6 1.1 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KUM59922.1 - 2.1e-97 326.2 0.0 2.9e-96 322.5 0.0 2.2 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KUM59922.1 - 2.4e-19 69.6 0.1 5e-19 68.6 0.1 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2808 PF10989.3 KUM59922.1 - 0.048 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) Aminotran_5 PF00266.14 KUM59924.1 - 5.5e-26 91.1 0.0 8.3e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.11 KUM59924.1 - 6.9e-26 90.3 0.0 1.3e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 KUM59924.1 - 1.7e-20 72.8 0.0 3.1e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 MOSC domain Pyridoxal_deC PF00282.14 KUM59925.1 - 1.3e-70 237.7 0.0 1.6e-70 237.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Rubis-subs-bind PF09273.6 KUM59925.1 - 0.11 12.3 0.0 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 Rubisco LSMT substrate-binding MFS_1 PF07690.11 KUM59926.1 - 1.7e-45 155.2 52.4 2.3e-43 148.2 22.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KUM59926.1 - 7e-05 21.2 3.7 7e-05 21.2 2.6 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) TPR_11 PF13414.1 KUM59927.1 - 5e-10 38.8 2.6 0.0035 16.9 0.1 4.4 4 1 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 KUM59927.1 - 9.3e-10 37.6 9.8 0.12 12.3 0.0 6.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.23 KUM59927.1 - 3.7e-06 26.2 1.2 4.3 7.1 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KUM59927.1 - 9.5e-06 25.4 3.2 0.0013 18.6 0.0 4.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 KUM59927.1 - 0.0014 19.2 12.4 1.8 9.3 1.0 5.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 KUM59927.1 - 0.0019 17.8 0.9 13 5.8 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 KUM59927.1 - 0.0024 18.1 10.3 0.45 11.0 0.5 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KUM59927.1 - 0.0084 15.8 0.1 2.2 8.2 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KUM59927.1 - 0.012 16.2 9.7 11 7.0 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 KUM59927.1 - 0.73 9.8 6.0 2.5 8.1 0.3 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_28 PF00295.12 KUM59928.1 - 2.5e-50 171.2 5.8 3.6e-50 170.7 4.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF4528 PF15031.1 KUM59928.1 - 0.025 14.3 0.0 0.057 13.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4528) YabP PF07873.6 KUM59928.1 - 0.039 13.4 0.5 0.15 11.6 0.1 2.2 3 0 0 3 3 3 0 YabP family MAPEG PF01124.13 KUM59929.1 - 1e-13 51.0 1.8 1.5e-13 50.4 1.3 1.2 1 0 0 1 1 1 1 MAPEG family p450 PF00067.17 KUM59930.1 - 8.2e-73 245.4 0.0 1e-72 245.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KUM59931.1 - 6.6e-31 107.3 29.5 6.6e-31 107.3 20.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM59931.1 - 1.1e-10 40.7 9.6 1.1e-10 40.7 6.6 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 KUM59931.1 - 1.1e-07 30.4 3.0 2.1e-07 29.5 2.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Abhydrolase_3 PF07859.8 KUM59932.1 - 1.4e-22 80.2 0.0 2e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KUM59932.1 - 1.5e-15 56.7 0.0 2.1e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KUM59932.1 - 1e-05 25.3 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KUM59932.1 - 0.011 14.9 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family adh_short PF00106.20 KUM59933.1 - 1e-23 84.0 0.2 2.6e-23 82.7 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM59933.1 - 7.7e-08 32.3 0.0 1.1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM59933.1 - 9.8e-08 31.8 1.4 2e-06 27.5 1.0 2.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM59933.1 - 0.0037 16.7 0.1 0.0054 16.1 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KUM59933.1 - 0.0039 17.2 0.0 0.009 16.0 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Skp1 PF01466.14 KUM59933.1 - 0.024 14.6 0.0 0.57 10.2 0.0 2.4 2 0 0 2 2 2 0 Skp1 family, dimerisation domain Urocanase PF01175.13 KUM59933.1 - 0.037 12.0 0.1 0.11 10.5 0.0 1.6 1 1 0 2 2 2 0 Urocanase 2-Hacid_dh_C PF02826.14 KUM59933.1 - 0.062 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lipase_3 PF01764.20 KUM59934.1 - 4.6e-31 107.3 0.0 6.9e-31 106.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KUM59934.1 - 0.0046 16.7 0.0 0.0061 16.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KUM59934.1 - 0.0049 16.1 0.0 0.0076 15.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase3_N PF03893.11 KUM59934.1 - 0.021 14.6 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipase 3 N-terminal region DUF2048 PF09752.4 KUM59934.1 - 0.088 11.6 0.1 0.13 11.0 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) DUF2974 PF11187.3 KUM59934.1 - 0.15 11.4 0.4 0.35 10.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Pyr_redox_3 PF13738.1 KUM59935.1 - 1.3e-26 93.8 0.0 3.6e-26 92.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KUM59935.1 - 3e-16 58.7 0.0 2.9e-15 55.4 0.0 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KUM59935.1 - 1.5e-12 47.3 0.1 1e-09 38.2 0.0 3.1 4 0 0 4 4 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KUM59935.1 - 1.3e-07 30.8 0.0 3.7e-05 22.7 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 KUM59935.1 - 3.9e-07 29.4 0.0 9.6e-05 21.5 0.0 2.4 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 KUM59935.1 - 1.4e-06 27.4 0.0 0.00067 18.6 0.0 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KUM59935.1 - 1.5e-06 28.2 0.0 0.048 13.5 0.0 3.4 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KUM59935.1 - 7.4e-05 21.8 0.0 0.005 15.8 0.0 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.22 KUM59935.1 - 0.00011 22.5 0.0 0.025 14.9 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM59935.1 - 0.00035 20.3 0.3 0.17 11.6 0.0 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 KUM59935.1 - 0.00095 19.2 0.0 0.062 13.4 0.0 3.1 4 0 0 4 4 4 1 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 KUM59935.1 - 0.0059 15.7 0.0 0.54 9.2 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KUM59935.1 - 0.012 14.6 0.0 0.5 9.3 0.0 2.2 1 1 1 2 2 2 0 Flavin containing amine oxidoreductase GIDA PF01134.17 KUM59935.1 - 0.016 14.0 0.3 1.3 7.7 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KUM59935.1 - 0.025 13.4 0.0 0.14 10.9 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.1 KUM59935.1 - 0.047 13.9 0.0 0.17 12.1 0.0 1.9 2 0 0 2 2 1 0 Putative NAD(P)-binding Trp_halogenase PF04820.9 KUM59935.1 - 0.15 10.6 0.1 4.8 5.6 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase PTR2 PF00854.16 KUM59936.1 - 1.6e-38 132.5 14.5 1.3e-37 129.5 10.0 2.1 1 1 0 1 1 1 1 POT family DUF1115 PF06544.7 KUM59938.1 - 0.0023 17.6 0.0 0.0032 17.1 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1115) Fungal_trans PF04082.13 KUM59939.1 - 4e-20 71.7 0.1 4e-20 71.7 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain ABC2_membrane PF01061.19 KUM59940.1 - 2e-75 252.5 54.3 1e-40 139.1 18.2 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KUM59940.1 - 1.6e-36 125.5 0.0 5.5e-17 62.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KUM59940.1 - 1.7e-25 88.6 0.1 1.7e-25 88.6 0.1 3.2 3 0 0 3 3 2 2 CDR ABC transporter AAA_25 PF13481.1 KUM59940.1 - 7.8e-09 35.2 0.1 0.00064 19.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain ABC2_membrane_3 PF12698.2 KUM59940.1 - 9.5e-08 31.4 39.1 3e-05 23.2 12.5 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.1 KUM59940.1 - 6e-06 26.3 2.0 0.00012 22.1 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 KUM59940.1 - 7.3e-06 26.1 0.1 0.0067 16.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 KUM59940.1 - 2e-05 24.0 1.0 0.0016 17.9 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 KUM59940.1 - 4.6e-05 22.6 0.0 0.0048 16.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KUM59940.1 - 0.0003 20.7 0.0 0.054 13.4 0.0 2.8 3 0 0 3 3 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KUM59940.1 - 0.00092 18.7 0.1 0.27 10.6 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 KUM59940.1 - 0.0015 18.6 1.2 0.24 11.5 0.1 3.5 4 1 0 4 4 4 1 AAA domain AAA_33 PF13671.1 KUM59940.1 - 0.004 17.0 0.0 0.27 11.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain Miro PF08477.8 KUM59940.1 - 0.0047 17.4 0.0 0.18 12.2 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 KUM59940.1 - 0.007 16.6 0.1 0.026 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KUM59940.1 - 0.027 13.8 0.6 4.4 6.6 0.2 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 KUM59940.1 - 0.034 14.9 0.0 0.25 12.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 KUM59940.1 - 0.048 12.7 0.0 0.18 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 KUM59940.1 - 0.049 13.9 0.2 0.11 12.7 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KUM59940.1 - 0.051 13.1 0.7 2.8 7.4 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KUM59940.1 - 0.056 13.4 0.0 0.19 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_trans_N PF14510.1 KUM59940.1 - 0.092 12.8 0.0 0.26 11.4 0.0 1.8 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal SMC_N PF02463.14 KUM59940.1 - 0.1 11.8 0.0 11 5.1 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain cobW PF02492.14 KUM59940.1 - 0.14 11.5 0.9 0.67 9.3 0.0 2.3 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 KUM59940.1 - 0.18 10.5 0.3 1.6 7.4 0.0 2.1 2 0 0 2 2 2 0 ArgK protein UPF0079 PF02367.12 KUM59940.1 - 0.19 11.3 0.5 12 5.5 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KUM59940.1 - 0.2 11.2 0.4 6 6.5 0.1 2.6 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.18 KUM59940.1 - 0.25 11.1 0.6 1.4 8.7 0.0 2.4 3 0 0 3 3 3 0 Dynamin family Zeta_toxin PF06414.7 KUM59940.1 - 0.45 9.5 0.4 11 4.9 0.2 2.4 2 0 0 2 2 2 0 Zeta toxin ABC_ATPase PF09818.4 KUM59940.1 - 0.47 8.9 0.0 0.83 8.1 0.0 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class PALP PF00291.20 KUM59941.1 - 7.8e-69 232.2 0.2 9.4e-69 231.9 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Isochorismatase PF00857.15 KUM59942.1 - 3.3e-40 137.8 0.1 3.7e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family CheW PF01584.14 KUM59942.1 - 0.034 13.5 0.0 0.1 12.0 0.0 1.8 2 0 0 2 2 2 0 CheW-like domain Ribonuc_L-PSP PF01042.16 KUM59943.1 - 5.4e-16 58.4 0.0 6.2e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP ATP-grasp_4 PF13535.1 KUM59944.1 - 0.012 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain Glyco_transf_8 PF01501.15 KUM59945.1 - 0.0029 16.9 3.4 0.015 14.6 2.3 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KUM59945.1 - 0.097 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative PfkB PF00294.19 KUM59946.1 - 3e-36 125.1 0.4 3.5e-36 124.8 0.3 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF498 PF04430.9 KUM59946.1 - 0.053 13.0 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) PARP PF00644.15 KUM59947.1 - 4.2e-62 209.2 1.2 1.3e-61 207.6 0.0 2.2 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 KUM59947.1 - 1.4e-39 134.8 0.1 2.5e-39 134.0 0.1 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 KUM59947.1 - 1.6e-17 63.2 0.1 1.6e-17 63.2 0.1 2.3 2 0 0 2 2 2 1 WGR domain PTCB-BRCT PF12738.2 KUM59947.1 - 6.2e-08 32.3 0.2 1.4e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KUM59947.1 - 1e-06 28.7 0.1 3.3e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Anophelin PF10731.4 KUM59947.1 - 0.12 12.4 1.6 0.51 10.4 1.1 2.1 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito DUF4407 PF14362.1 KUM59947.1 - 2.5 6.9 7.5 4.3 6.2 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fungal_trans_2 PF11951.3 KUM59948.1 - 4e-11 42.1 0.1 9.1e-11 40.9 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM59949.1 - 9.6e-10 38.2 9.4 1.5e-09 37.6 6.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KUM59950.1 - 0.048 12.2 0.0 0.061 11.9 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Sugar_tr PF00083.19 KUM59951.1 - 7.8e-105 351.0 34.4 2.5e-104 349.3 23.8 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM59951.1 - 3.7e-20 71.9 60.4 7.9e-14 51.1 17.8 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 KUM59951.1 - 0.39 9.0 45.4 0.066 11.6 8.6 3.3 2 2 1 3 3 3 0 MFS/sugar transport protein TFIIF_beta PF02270.10 KUM59952.1 - 1e-81 274.7 0.3 1.2e-81 274.5 0.2 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit DUF859 PF05895.7 KUM59952.1 - 0.013 13.8 0.0 0.017 13.4 0.0 1.1 1 0 0 1 1 1 0 Siphovirus protein of unknown function (DUF859) MFS_1 PF07690.11 KUM59953.1 - 6.7e-39 133.5 38.8 1.1e-38 132.9 26.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM59953.1 - 0.006 15.2 33.2 0.063 11.8 23.1 2.9 1 1 0 1 1 1 1 Sugar (and other) transporter Patatin PF01734.17 KUM59954.1 - 3.6e-06 27.0 0.0 5.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3603 PF12227.3 KUM59954.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) NAD_binding_4 PF07993.7 KUM59955.1 - 8.6e-32 110.0 0.0 1.2e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KUM59955.1 - 0.1 12.5 0.1 0.57 10.0 0.0 2.3 2 1 0 2 2 2 0 short chain dehydrogenase Acyl_transf_1 PF00698.16 KUM59956.1 - 1.7e-68 231.2 0.0 2.7e-68 230.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KUM59956.1 - 1.7e-57 193.9 0.9 3.2e-57 193.1 0.6 1.5 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 KUM59956.1 - 4.2e-53 180.4 0.0 6.8e-53 179.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KUM59956.1 - 1.4e-44 151.9 1.1 1.4e-44 151.9 0.8 1.9 2 0 0 2 2 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KUM59956.1 - 7.5e-26 90.3 0.3 2.3e-25 88.7 0.2 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KUM59956.1 - 3.2e-17 62.8 0.0 1.1e-16 61.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KUM59956.1 - 3.9e-17 62.0 0.0 1.4e-16 60.2 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KUM59956.1 - 2.1e-13 50.3 0.0 5.4e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM59956.1 - 4.5e-11 43.0 0.0 2.1e-10 40.9 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KUM59956.1 - 7.7e-11 42.9 0.0 4.2e-10 40.5 0.0 2.3 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KUM59956.1 - 8.3e-10 39.2 0.0 2.2e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM59956.1 - 2e-09 37.2 0.0 4e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 KUM59956.1 - 1.9e-07 30.8 0.2 7.5e-07 28.8 0.1 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.13 KUM59956.1 - 5e-06 25.7 0.0 9.9e-06 24.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 KUM59956.1 - 7.6e-05 22.9 0.0 0.00021 21.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ketoacyl-synt PF00109.21 KUM59956.1 - 0.00012 21.6 0.5 0.0003 20.3 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Methyltransf_26 PF13659.1 KUM59956.1 - 0.00018 21.5 0.0 0.00053 20.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM59956.1 - 0.00036 20.8 0.0 0.0011 19.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KUM59956.1 - 0.0041 16.5 0.2 0.022 14.2 0.0 2.2 3 0 0 3 3 3 1 Putative methyltransferase 3Beta_HSD PF01073.14 KUM59956.1 - 0.0044 15.7 0.0 0.0075 15.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_24 PF13578.1 KUM59956.1 - 0.067 14.0 0.0 0.88 10.4 0.0 2.9 2 0 0 2 2 2 0 Methyltransferase domain Macoilin PF09726.4 KUM59957.1 - 3.4e-06 25.6 5.8 3.4e-06 25.6 4.0 1.8 2 0 0 2 2 2 1 Transmembrane protein bZIP_2 PF07716.10 KUM59957.1 - 0.0063 16.3 22.7 1.4 8.8 11.7 2.8 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 KUM59957.1 - 0.013 15.4 25.3 0.019 14.9 10.9 2.8 2 1 1 3 3 3 0 bZIP transcription factor DUF3450 PF11932.3 KUM59957.1 - 0.03 13.6 12.8 0.062 12.5 8.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) bZIP_Maf PF03131.12 KUM59957.1 - 0.7 10.2 21.8 0.084 13.1 9.9 2.8 1 1 1 2 2 2 0 bZIP Maf transcription factor V_ATPase_I PF01496.14 KUM59957.1 - 1.4 6.7 11.2 2 6.1 7.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMEM192 PF14802.1 KUM59957.1 - 2.1 7.1 4.7 3.2 6.5 3.2 1.3 1 0 0 1 1 1 0 TMEM192 family zf-CCCH PF00642.19 KUM59958.1 - 8.3e-17 60.4 30.9 7.9e-06 25.4 0.9 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ebp2 PF05890.7 KUM59958.1 - 0.16 11.2 4.3 0.33 10.2 3.0 1.4 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 LRV_FeS PF05484.6 KUM59958.1 - 0.59 9.7 7.3 2.6 7.6 0.2 3.5 2 1 1 3 3 3 0 LRV protein FeS4 cluster zf-C3H1 PF10650.4 KUM59958.1 - 3.6 7.1 8.7 0.29 10.6 0.1 3.0 3 0 0 3 3 3 0 Putative zinc-finger domain BTB PF00651.26 KUM59959.1 - 0.00072 19.5 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Zip PF02535.17 KUM59960.1 - 2e-49 168.3 0.2 2.3e-49 168.1 0.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Ala_racemase_N PF01168.15 KUM59961.1 - 4.2e-26 91.8 0.0 5.1e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.1 KUM59961.1 - 8.6e-20 70.7 0.0 1.8e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain SDH_alpha PF03313.10 KUM59961.1 - 0.019 13.9 0.8 4.1 6.3 0.7 2.2 2 0 0 2 2 2 0 Serine dehydratase alpha chain Glyco_hydro_16 PF00722.16 KUM59962.1 - 1.7e-09 37.2 0.2 3.7e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Reovirus_M2 PF05993.7 KUM59962.1 - 0.043 11.6 0.0 0.061 11.1 0.0 1.1 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Zn_clus PF00172.13 KUM59963.1 - 0.00016 21.5 11.4 0.00016 21.5 7.9 2.4 1 1 1 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain DIE2_ALG10 PF04922.7 KUM59963.1 - 0.054 12.5 2.4 0.085 11.8 1.7 1.2 1 0 0 1 1 1 0 DIE2/ALG10 family Dickkopf_N PF04706.7 KUM59963.1 - 3.7 7.7 16.3 6.6 6.9 2.3 2.8 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region p450 PF00067.17 KUM59964.1 - 1.7e-64 218.0 0.0 2.1e-64 217.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_28 PF03033.15 KUM59965.1 - 1.7e-24 86.1 0.0 4e-24 84.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain zf-Tim10_DDP PF02953.10 KUM59965.1 - 0.14 11.4 0.1 0.22 10.8 0.1 1.3 1 0 0 1 1 1 0 Tim10/DDP family zinc finger Transferase PF02458.10 KUM59966.1 - 1.5e-33 115.8 0.0 2.1e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Transferase family Condensation PF00668.15 KUM59966.1 - 0.00046 19.1 0.0 0.00079 18.3 0.0 1.3 1 0 0 1 1 1 1 Condensation domain MFS_1 PF07690.11 KUM59968.1 - 1.4e-18 66.7 42.5 2e-13 49.8 15.4 3.3 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 KUM59968.1 - 1e-14 53.6 12.4 1.8e-14 52.9 8.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DAO PF01266.19 KUM59970.1 - 6.1e-23 81.3 0.0 6.8e-23 81.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KUM59970.1 - 0.0005 20.0 0.1 0.00079 19.3 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KUM59970.1 - 0.0074 16.0 0.1 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KUM59970.1 - 0.012 15.5 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KUM59970.1 - 0.012 14.4 0.0 0.027 13.3 0.0 1.6 1 1 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 KUM59970.1 - 0.05 12.6 0.0 0.083 11.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 KUM59970.1 - 0.076 13.4 0.1 0.36 11.2 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KUM59970.1 - 0.13 12.5 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPGT PF00201.13 KUM59971.1 - 0.012 14.1 0.0 0.019 13.5 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.6 KUM59971.1 - 0.093 12.8 0.0 1.9 8.7 0.0 2.8 3 0 0 3 3 3 0 ATG C terminal domain Glyco_tran_28_C PF04101.11 KUM59971.1 - 0.14 11.8 0.0 0.31 10.6 0.0 1.5 1 1 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain ABC_tran PF00005.22 KUM59972.1 - 1.4e-42 145.1 0.0 1e-21 77.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KUM59972.1 - 5.8e-23 81.6 22.5 2e-22 79.9 8.1 2.9 4 0 0 4 4 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 KUM59972.1 - 7.7e-14 52.3 0.9 2.3e-05 24.5 0.1 4.3 2 2 0 3 3 3 2 AAA domain SMC_N PF02463.14 KUM59972.1 - 6.8e-11 41.8 0.9 0.0047 16.1 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KUM59972.1 - 1.4e-08 34.9 0.3 0.0068 16.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KUM59972.1 - 1.5e-07 30.8 0.2 0.0053 16.2 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KUM59972.1 - 4.3e-07 30.7 0.0 0.0098 16.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KUM59972.1 - 1e-06 28.9 0.2 0.026 14.6 0.0 3.1 2 1 0 2 2 2 2 AAA domain T2SE PF00437.15 KUM59972.1 - 1.7e-06 27.1 0.1 0.0026 16.7 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_18 PF13238.1 KUM59972.1 - 4.5e-06 26.9 0.1 0.045 14.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 KUM59972.1 - 5.6e-06 26.1 0.6 0.048 13.3 0.1 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KUM59972.1 - 2.1e-05 24.0 0.4 0.0053 16.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_23 PF13476.1 KUM59972.1 - 5.8e-05 23.4 0.2 0.15 12.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 KUM59972.1 - 6.4e-05 23.1 0.0 0.063 13.4 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 KUM59972.1 - 9.4e-05 21.6 0.1 0.31 10.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 KUM59972.1 - 9.5e-05 22.2 0.6 0.33 10.9 0.0 2.9 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Miro PF08477.8 KUM59972.1 - 9.7e-05 22.8 0.1 0.019 15.4 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein DUF87 PF01935.12 KUM59972.1 - 0.00013 21.9 1.3 0.0013 18.6 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 KUM59972.1 - 0.00022 21.1 0.2 0.16 11.9 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.1 KUM59972.1 - 0.00049 19.9 2.8 0.056 13.3 0.2 2.8 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KUM59972.1 - 0.00055 19.6 0.6 0.027 14.2 0.1 2.7 2 0 0 2 2 2 1 Part of AAA domain cobW PF02492.14 KUM59972.1 - 0.00057 19.3 0.3 0.12 11.8 0.2 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 KUM59972.1 - 0.0012 18.0 0.0 0.59 9.1 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin FtsK_SpoIIIE PF01580.13 KUM59972.1 - 0.002 17.6 0.1 0.26 10.7 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_10 PF12846.2 KUM59972.1 - 0.0023 17.4 0.9 0.72 9.2 0.1 2.4 2 0 0 2 2 2 1 AAA-like domain NACHT PF05729.7 KUM59972.1 - 0.0028 17.3 0.1 0.61 9.7 0.0 2.8 3 0 0 3 3 2 1 NACHT domain Dynamin_N PF00350.18 KUM59972.1 - 0.0029 17.4 0.5 1.5 8.6 0.1 2.4 2 0 0 2 2 2 1 Dynamin family ATP_bind_1 PF03029.12 KUM59972.1 - 0.004 16.7 0.3 0.098 12.1 0.1 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Adeno_IVa2 PF02456.10 KUM59972.1 - 0.0054 15.4 0.1 0.39 9.3 0.0 2.2 2 0 0 2 2 2 1 Adenovirus IVa2 protein PduV-EutP PF10662.4 KUM59972.1 - 0.0072 15.8 0.5 0.084 12.3 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 KUM59972.1 - 0.01 15.5 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase GTP_EFTU PF00009.22 KUM59972.1 - 0.024 14.0 0.2 3 7.2 0.0 3.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain RNA_helicase PF00910.17 KUM59972.1 - 0.033 14.3 0.0 13 6.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase UPF0079 PF02367.12 KUM59972.1 - 0.044 13.4 0.1 0.74 9.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_5 PF07728.9 KUM59972.1 - 0.051 13.3 0.4 14 5.4 0.1 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KUM59972.1 - 0.052 12.9 0.2 27 4.1 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 KUM59972.1 - 0.06 12.5 0.8 7.9 5.5 0.0 2.5 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI DEAD PF00270.24 KUM59972.1 - 0.098 12.1 0.1 3.8 6.9 0.0 2.6 3 0 0 3 3 2 0 DEAD/DEAH box helicase AAA_24 PF13479.1 KUM59972.1 - 0.11 12.0 0.5 3.2 7.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KUM59972.1 - 0.13 11.8 0.0 7.7 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 KUM59972.1 - 0.16 10.9 0.0 2.1 7.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.4 KUM59972.1 - 0.21 10.1 0.1 16 3.9 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Guanylate_kin PF00625.16 KUM59972.1 - 0.22 10.9 0.1 0.88 8.9 0.0 2.1 2 1 0 2 2 2 0 Guanylate kinase NTPase_1 PF03266.10 KUM59972.1 - 0.41 10.3 3.2 5.3 6.7 0.1 2.8 3 0 0 3 3 3 0 NTPase AAA_28 PF13521.1 KUM59972.1 - 0.58 10.1 0.9 10 6.0 0.4 2.3 2 0 0 2 2 2 0 AAA domain adh_short PF00106.20 KUM59974.1 - 1.2e-13 51.2 0.0 2e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM59974.1 - 6.5e-09 35.6 0.0 1.3e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 KR domain 2OG-FeII_Oxy_2 PF13532.1 KUM59975.1 - 1e-17 64.6 0.0 1.3e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KUM59975.1 - 2.6e-09 37.2 0.0 5.4e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KUM59975.1 - 0.018 15.5 0.1 0.14 12.6 0.0 2.4 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Epimerase PF01370.16 KUM59977.1 - 2e-13 50.3 0.0 2.9e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KUM59977.1 - 1.8e-08 34.6 2.8 9.2e-07 29.0 1.9 2.9 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KUM59977.1 - 8e-05 21.4 0.0 0.00012 20.9 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KUM59977.1 - 0.0011 18.2 0.1 0.0017 17.6 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 KUM59977.1 - 0.0024 16.8 0.1 0.0037 16.2 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein UDPG_MGDP_dh_N PF03721.9 KUM59977.1 - 0.021 14.1 0.1 0.048 13.0 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_4 PF07993.7 KUM59977.1 - 0.04 12.8 0.5 0.16 10.8 0.2 2.1 2 1 0 2 2 2 0 Male sterility protein DAO PF01266.19 KUM59979.1 - 2.8e-11 42.9 0.3 3.4e-11 42.6 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Podoplanin PF05808.6 KUM59980.1 - 0.00056 19.5 0.7 0.001 18.6 0.5 1.4 1 0 0 1 1 1 1 Podoplanin Peptidase_M22 PF00814.20 KUM59980.1 - 0.00058 19.4 0.0 0.00088 18.8 0.0 1.3 1 0 0 1 1 1 1 Glycoprotease family Glycophorin_A PF01102.13 KUM59980.1 - 0.0026 17.5 0.0 0.0071 16.1 0.0 1.8 2 0 0 2 2 2 1 Glycophorin A TMEM154 PF15102.1 KUM59980.1 - 0.033 13.8 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF1735 PF08522.5 KUM59980.1 - 0.042 14.2 0.1 0.078 13.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1735) MGC-24 PF05283.6 KUM59980.1 - 1.9 8.2 11.2 2.9 7.6 7.8 1.3 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Med3 PF11593.3 KUM59981.1 - 6 6.0 19.0 8.9 5.4 13.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PAP1 PF08601.5 KUM59981.1 - 6.7 6.2 12.1 8.4 5.9 8.4 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Peptidase_S64 PF08192.6 KUM59981.1 - 7.4 4.7 9.3 9.1 4.4 6.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 p450 PF00067.17 KUM59982.1 - 1.3e-21 76.7 0.0 2.9e-21 75.5 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Acyltransferase PF01553.16 KUM59984.1 - 1.6e-30 105.2 0.0 2.7e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase ACC_central PF08326.7 KUM59985.1 - 4.9e-257 854.6 0.0 6.3e-257 854.2 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 KUM59985.1 - 8.6e-182 604.8 0.0 1.6e-181 603.9 0.0 1.4 2 0 0 2 2 2 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 KUM59985.1 - 3.8e-53 179.9 0.0 7.8e-53 178.8 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KUM59985.1 - 5.6e-24 84.3 0.1 1.1e-23 83.4 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KUM59985.1 - 1.3e-23 82.9 0.0 1.2e-19 70.2 0.0 3.8 4 0 0 4 4 3 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 KUM59985.1 - 4.5e-16 58.2 0.1 1.2e-15 56.9 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 KUM59985.1 - 7.9e-12 45.2 0.0 1.8e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KUM59985.1 - 5.3e-09 35.2 0.0 0.008 14.9 0.0 3.2 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KUM59985.1 - 7.5e-06 25.4 0.0 1.9e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 KUM59985.1 - 0.00021 21.1 0.0 0.00082 19.2 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.6 KUM59985.1 - 0.12 11.7 0.0 2.5 7.5 0.0 2.3 2 0 0 2 2 2 0 RimK-like ATP-grasp domain CorA PF01544.13 KUM59987.1 - 0.26 10.2 1.7 0.79 8.7 1.3 1.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF883 PF05957.8 KUM59987.1 - 0.3 11.5 0.0 0.3 11.5 0.0 8.2 7 2 2 10 10 10 0 Bacterial protein of unknown function (DUF883) Peptidase_S64 PF08192.6 KUM59988.1 - 0.011 14.1 0.0 0.082 11.2 0.0 2.0 2 0 0 2 2 2 0 Peptidase family S64 DUF523 PF04463.7 KUM59988.1 - 0.15 11.7 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF523) RINGv PF12906.2 KUM59989.1 - 1.7e-15 56.7 10.5 2.9e-15 56.0 7.3 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_4 PF14570.1 KUM59989.1 - 0.18 11.4 6.2 0.3 10.6 4.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 KUM59989.1 - 0.38 10.4 5.6 0.68 9.6 3.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KUM59989.1 - 1 9.2 9.6 1.8 8.4 6.6 1.4 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.3 KUM59989.1 - 1.6 8.7 6.3 3 7.8 4.4 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain F-box-like PF12937.2 KUM59993.1 - 2.9e-07 30.0 0.2 1.4e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KUM59993.1 - 0.006 16.2 0.2 0.038 13.6 0.0 2.2 2 0 0 2 2 2 1 F-box domain PduL PF06130.7 KUM59993.1 - 0.072 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Propanediol utilisation protein PduL DUF788 PF05620.6 KUM59994.1 - 2.7e-47 160.7 0.0 3.1e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) TPR_1 PF00515.23 KUM59995.1 - 2.7e-45 150.1 19.7 3.8e-08 32.5 0.0 9.7 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 KUM59995.1 - 2.9e-41 136.0 21.1 1.3e-05 24.7 0.0 10.1 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_11 PF13414.1 KUM59995.1 - 1.5e-40 136.6 24.6 3.1e-11 42.7 2.2 7.7 4 1 4 8 8 8 8 TPR repeat TPR_16 PF13432.1 KUM59995.1 - 1.9e-30 104.8 23.8 1.5e-08 35.0 0.1 8.6 6 3 2 8 8 8 7 Tetratricopeptide repeat Apc3 PF12895.2 KUM59995.1 - 1.3e-29 102.1 18.6 2.5e-19 69.2 0.7 4.4 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KUM59995.1 - 1.6e-27 93.2 0.9 0.0016 18.0 0.1 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.1 KUM59995.1 - 1.8e-22 79.0 21.5 4.4e-05 23.3 0.5 7.8 4 2 3 8 8 8 7 Tetratricopeptide repeat TPR_19 PF14559.1 KUM59995.1 - 4.8e-22 78.0 11.2 3.7e-07 30.3 0.2 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 KUM59995.1 - 4e-21 73.5 7.1 0.088 13.4 0.0 9.1 6 1 3 9 9 8 5 Tetratricopeptide repeat TPR_17 PF13431.1 KUM59995.1 - 3e-14 51.9 13.4 0.05 13.8 0.0 9.0 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_7 PF13176.1 KUM59995.1 - 1.1e-11 43.5 5.3 0.0024 17.5 0.0 7.7 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 KUM59995.1 - 3.1e-11 42.9 4.9 0.16 12.4 0.1 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_21 PF09976.4 KUM59995.1 - 0.00055 19.9 5.2 0.017 15.0 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 KUM59995.1 - 0.013 15.2 8.3 5.5 6.9 0.1 5.5 4 1 3 7 7 6 0 Tetratricopeptide repeat MIT PF04212.13 KUM59995.1 - 0.023 14.5 2.5 1.3 8.9 0.1 4.2 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain Sel1 PF08238.7 KUM59995.1 - 0.068 13.8 8.1 8.8 7.1 0.1 6.4 8 0 0 8 8 8 0 Sel1 repeat ChAPs PF09295.5 KUM59995.1 - 0.14 10.8 1.2 10 4.7 0.1 2.3 1 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) APP_E2 PF12925.2 KUM59995.1 - 0.2 11.1 3.0 0.26 10.8 0.2 2.4 2 1 0 2 2 2 0 E2 domain of amyloid precursor protein DUF2225 PF09986.4 KUM59995.1 - 5.6 6.3 11.6 2 7.8 0.1 4.0 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) MFS_1 PF07690.11 KUM59997.1 - 1.3e-31 109.5 65.0 9.9e-31 106.7 41.9 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3333 PF11812.3 KUM59998.1 - 0.22 11.5 0.5 0.3 11.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) NUDE_C PF04880.8 KUM60000.1 - 5.1e-31 108.2 5.4 5.1e-31 108.2 3.7 4.6 3 1 2 5 5 2 1 NUDE protein, C-terminal conserved region WEMBL PF05701.6 KUM60000.1 - 0.0028 16.1 22.2 0.0041 15.6 15.4 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light DUF904 PF06005.7 KUM60000.1 - 0.0079 16.4 6.5 0.0079 16.4 4.5 4.2 2 1 1 3 3 2 1 Protein of unknown function (DUF904) Myosin_tail_1 PF01576.14 KUM60000.1 - 0.026 12.2 27.3 0.036 11.7 18.9 1.1 1 0 0 1 1 1 0 Myosin tail Cep57_MT_bd PF06657.8 KUM60000.1 - 0.4 10.6 20.2 0.27 11.1 3.5 4.1 2 1 2 4 4 4 0 Centrosome microtubule-binding domain of Cep57 Filament PF00038.16 KUM60000.1 - 0.43 10.0 29.0 2.4 7.5 8.5 2.9 1 1 2 3 3 3 0 Intermediate filament protein CENP-F_leu_zip PF10473.4 KUM60000.1 - 0.51 10.2 30.2 5.8 6.7 7.7 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.3 KUM60000.1 - 0.58 10.0 30.3 0.51 10.2 2.4 3.4 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Tho2 PF11262.3 KUM60000.1 - 0.68 8.9 15.3 1.2 8.0 1.1 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF745 PF05335.8 KUM60000.1 - 0.79 9.2 8.8 1.4 8.3 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) ATG16 PF08614.6 KUM60000.1 - 1.3 8.8 35.0 0.078 12.8 10.6 3.0 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) IFT57 PF10498.4 KUM60000.1 - 2.1 7.0 20.1 0.2 10.3 10.2 1.8 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Peptidase_S46 PF10459.4 KUM60000.1 - 2.6 6.3 13.1 3.2 6.0 9.1 1.1 1 0 0 1 1 1 0 Peptidase S46 RTBV_P46 PF06216.6 KUM60000.1 - 6 5.6 12.3 2 7.1 0.4 2.2 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein DUF1664 PF07889.7 KUM60000.1 - 9.5 6.0 12.9 2.1 8.1 3.2 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Isochorismatase PF00857.15 KUM60002.1 - 6.2e-45 153.2 0.0 8.4e-45 152.8 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family GMC_oxred_N PF00732.14 KUM60003.1 - 2.9e-69 233.4 0.0 4.7e-69 232.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KUM60003.1 - 1e-29 103.6 0.0 1.8e-29 102.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KUM60003.1 - 1e-05 24.6 0.1 1.6e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KUM60003.1 - 1.3e-05 25.3 0.3 0.038 14.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KUM60003.1 - 1.9e-05 23.7 0.0 0.0002 20.4 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KUM60003.1 - 4.4e-05 23.4 0.0 0.00024 21.0 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KUM60003.1 - 0.00012 21.0 0.3 0.00081 18.3 0.2 2.2 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KUM60003.1 - 0.0054 16.6 0.1 0.033 14.0 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KUM60003.1 - 0.045 12.2 0.0 0.081 11.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 KUM60003.1 - 0.087 12.5 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 KUM60003.1 - 0.18 12.2 0.1 0.41 11.0 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyoxalase_2 PF12681.2 KUM60004.1 - 0.0007 20.1 0.0 0.00073 20.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Acetyltransf_1 PF00583.19 KUM60005.1 - 1.3e-09 37.9 0.0 3.5e-09 36.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KUM60005.1 - 5.2e-07 29.7 0.0 1.1e-06 28.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 KUM60005.1 - 3.8e-06 27.4 0.0 6.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KUM60005.1 - 0.00024 20.8 0.0 0.00041 20.1 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 KUM60005.1 - 0.0094 15.6 0.1 0.3 10.8 0.0 2.4 1 1 0 1 1 1 1 FR47-like protein GNAT_acetyltr_2 PF13718.1 KUM60005.1 - 0.025 13.8 0.0 0.032 13.5 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Acetyltransf_3 PF13302.1 KUM60005.1 - 0.061 13.4 0.0 0.096 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FYVE PF01363.16 KUM60006.1 - 6.3e-15 54.8 8.0 9.8e-15 54.2 5.5 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.11 KUM60006.1 - 0.047 13.5 9.4 0.091 12.6 6.5 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger IBR PF01485.16 KUM60006.1 - 1.1 9.1 6.8 0.072 12.9 0.9 1.8 2 0 0 2 2 2 0 IBR domain 2-Hacid_dh_C PF02826.14 KUM60007.1 - 6.7e-52 175.2 0.0 9.8e-52 174.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KUM60007.1 - 1e-28 99.4 0.0 1.2e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.16 KUM60007.1 - 0.0056 16.2 0.1 0.16 11.5 0.1 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 KUM60007.1 - 0.049 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.16 KUM60007.1 - 0.69 9.7 2.5 11 5.8 1.2 2.4 2 0 0 2 2 2 0 ThiF family Glycos_transf_1 PF00534.15 KUM60008.1 - 1.3e-35 122.3 0.0 1.8e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KUM60008.1 - 4.4e-14 52.7 0.0 8.2e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KUM60008.1 - 2.1e-10 40.7 0.0 4.9e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KUM60008.1 - 2e-08 34.5 0.6 4.3e-08 33.4 0.0 1.9 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 KUM60008.1 - 5.9e-05 22.8 0.0 0.00013 21.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 GST_N_3 PF13417.1 KUM60009.1 - 3.4e-10 39.9 0.1 1.4e-09 38.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KUM60009.1 - 8e-10 38.7 0.0 2.5e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KUM60009.1 - 1.2e-09 37.9 0.0 2.9e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KUM60009.1 - 2.4e-05 24.1 0.0 6.4e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KUM60009.1 - 6.1e-05 22.9 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KUM60009.1 - 8.3e-05 22.9 0.0 0.00019 21.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SAP18 PF06487.7 KUM60010.1 - 7.7e-42 141.9 0.0 9.5e-42 141.6 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Prp18 PF02840.10 KUM60011.1 - 4.9e-53 178.8 0.0 4.9e-53 178.8 0.0 1.7 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 KUM60011.1 - 1.5e-08 33.7 1.7 1.5e-08 33.7 1.2 2.8 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like CAF-1_p150 PF11600.3 KUM60011.1 - 0.43 9.9 25.5 0.92 8.8 17.7 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC27 PF09507.5 KUM60011.1 - 0.49 9.5 19.1 0.71 9.0 13.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 APG6 PF04111.7 KUM60011.1 - 4.2 6.3 9.5 8 5.4 6.6 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 eIF-3c_N PF05470.7 KUM60011.1 - 6.2 4.7 12.0 9.6 4.1 8.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Presenilin PF01080.12 KUM60011.1 - 7.8 5.1 6.5 11 4.6 4.5 1.2 1 0 0 1 1 1 0 Presenilin HD PF01966.17 KUM60012.1 - 4.5e-07 29.9 0.0 6.9e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 HD domain Nol1_Nop2_Fmu PF01189.12 KUM60013.1 - 9.8e-11 41.5 0.0 3.2e-06 26.7 0.0 2.3 2 0 0 2 2 2 2 NOL1/NOP2/sun family Ppx-GppA PF02541.11 KUM60014.1 - 4.6e-41 140.8 0.0 1.3e-40 139.4 0.0 1.6 1 1 0 1 1 1 1 Ppx/GppA phosphatase family Ferric_reduct PF01794.14 KUM60015.1 - 3.8e-20 72.2 16.2 6.3e-20 71.5 11.2 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KUM60015.1 - 4.2e-13 49.0 0.0 1.5e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.7 KUM60015.1 - 9.6e-11 41.8 0.0 2.1e-06 27.7 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 KUM60015.1 - 0.019 15.5 0.0 0.052 14.1 0.0 1.8 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain BNR_2 PF13088.1 KUM60016.1 - 4.1e-08 32.8 3.8 0.00047 19.5 0.1 2.9 1 1 2 3 3 3 2 BNR repeat-like domain BNR PF02012.15 KUM60016.1 - 0.0003 20.1 8.2 0.046 13.5 0.5 4.3 3 0 0 3 3 3 2 BNR/Asp-box repeat BTB_2 PF02214.17 KUM60017.1 - 4.6e-08 33.1 0.1 0.00013 22.1 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.26 KUM60017.1 - 0.077 12.9 0.0 4.6 7.2 0.0 2.4 2 0 0 2 2 2 0 BTB/POZ domain OPT PF03169.10 KUM60018.1 - 1.3e-159 532.6 48.2 1.4e-159 532.4 33.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CcmD PF04995.9 KUM60018.1 - 0.0034 17.0 0.2 0.0034 17.0 0.1 2.5 3 0 0 3 3 3 1 Heme exporter protein D (CcmD) Pyr_redox PF00070.22 KUM60019.1 - 1e-15 57.9 0.3 9.7e-13 48.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KUM60019.1 - 4.2e-11 43.0 0.0 3.9e-10 39.9 0.0 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KUM60019.1 - 1.1e-08 35.3 0.1 0.0039 17.2 0.0 3.1 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KUM60019.1 - 3.5e-06 26.1 0.0 1e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 KUM60019.1 - 0.044 12.6 0.0 0.084 11.7 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.19 KUM60019.1 - 0.1 11.5 0.2 0.1 11.5 0.2 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KUM60019.1 - 0.53 10.0 3.7 2.6 7.7 0.0 3.1 4 1 0 4 4 4 0 FAD-NAD(P)-binding GMC_oxred_N PF00732.14 KUM60020.1 - 5.5e-49 166.9 0.1 7.9e-49 166.3 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KUM60020.1 - 2.1e-29 102.6 0.2 1.3e-28 100.0 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 KUM60020.1 - 4.9e-09 35.5 0.1 1.2e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 KUM60020.1 - 6.2e-06 25.4 0.0 0.00011 21.3 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 KUM60020.1 - 7.1e-06 25.1 0.0 1.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KUM60020.1 - 8.8e-06 25.6 0.8 3e-05 23.9 0.2 2.3 3 0 0 3 3 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KUM60020.1 - 1.3e-05 24.3 0.0 2.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KUM60020.1 - 8.7e-05 22.4 0.1 0.00021 21.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KUM60020.1 - 0.018 13.5 0.1 0.035 12.5 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.2 KUM60020.1 - 0.031 13.3 0.4 0.047 12.7 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KUM60020.1 - 0.096 11.2 0.0 0.16 10.6 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase 3HCDH_N PF02737.13 KUM60020.1 - 0.14 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 KUM60020.1 - 0.14 10.9 0.0 0.34 9.7 0.0 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A GST_C PF00043.20 KUM60021.1 - 4.7e-13 48.9 0.0 7.8e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KUM60021.1 - 4.1e-12 46.1 0.0 7e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KUM60021.1 - 3.9e-10 39.7 0.0 6.8e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KUM60021.1 - 6.2e-09 35.6 0.1 1e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KUM60021.1 - 1.4e-08 35.1 0.1 2e-08 34.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KUM60021.1 - 4.6e-07 29.7 0.0 8.2e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Polysacc_deac_1 PF01522.16 KUM60022.1 - 1.3e-19 69.9 0.0 2e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.8 KUM60022.1 - 0.01 14.8 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase fn3_3 PF14686.1 KUM60023.1 - 5.2e-14 52.1 0.4 2e-13 50.2 0.1 2.3 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.1 KUM60023.1 - 2.7e-13 49.8 0.1 6.7e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III CarboxypepD_reg PF13620.1 KUM60023.1 - 8.6e-05 22.5 0.0 0.00028 20.8 0.0 1.9 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF2012 PF09430.5 KUM60023.1 - 0.0023 17.7 0.1 0.049 13.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2012) Hydrophobin PF01185.13 KUM60024.1 - 5.2e-09 36.4 10.8 6.5e-09 36.1 7.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Fungal_trans PF04082.13 KUM60026.1 - 7.9e-27 93.7 0.5 1.1e-26 93.2 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM60027.1 - 3.7e-09 36.3 7.1 5.9e-09 35.6 4.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KUM60027.1 - 5.1e-07 28.8 0.0 8.5e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.23 KUM60028.1 - 8.3e-100 334.0 0.0 1.1e-99 333.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KUM60028.1 - 3.9e-10 40.5 0.0 8.1e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RNB PF00773.14 KUM60029.1 - 1.5e-53 182.2 0.0 1.8e-51 175.3 0.0 2.3 1 1 0 1 1 1 1 RNB domain MARVEL PF01284.18 KUM60030.1 - 7.3e-05 22.6 0.7 9.8e-05 22.2 0.5 1.3 1 0 0 1 1 1 1 Membrane-associating domain S1FA PF04689.8 KUM60030.1 - 0.029 14.2 0.5 2.1 8.2 0.0 2.1 1 1 1 2 2 2 0 DNA binding protein S1FA Virul_fac_BrkB PF03631.10 KUM60030.1 - 0.066 12.5 0.7 0.078 12.3 0.5 1.1 1 0 0 1 1 1 0 Virulence factor BrkB PQ-loop PF04193.9 KUM60030.1 - 0.067 12.7 0.4 0.32 10.5 0.0 1.9 2 0 0 2 2 2 0 PQ loop repeat MFS_1 PF07690.11 KUM60031.1 - 2.3e-12 46.3 11.4 5.1e-12 45.1 7.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 KUM60032.1 - 7.8e-11 41.1 0.1 2.2e-10 39.7 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain EcKinase PF02958.15 KUM60033.1 - 2.9e-13 49.6 0.0 1.3e-12 47.4 0.0 1.8 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 KUM60033.1 - 3.7e-08 33.3 0.1 1.6e-07 31.3 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KUM60033.1 - 0.097 12.2 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Fungal_trans_2 PF11951.3 KUM60034.1 - 1.1e-09 37.3 2.2 1.8e-09 36.6 0.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM60034.1 - 1.8e-05 24.5 9.4 3.1e-05 23.7 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRP PF06011.7 KUM60036.1 - 4e-91 305.7 24.1 1.4e-90 303.9 16.7 1.8 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KUM60036.1 - 1.1e-06 28.7 0.0 1.7e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 ML-like domain DUF2873 PF11395.3 KUM60036.1 - 0.5 9.9 2.8 1.4 8.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2873) zf-RING_2 PF13639.1 KUM60037.1 - 5.3e-09 35.7 6.9 5.3e-09 35.7 4.8 2.6 2 1 1 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 KUM60037.1 - 0.00025 21.1 10.3 0.0018 18.3 5.5 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KUM60037.1 - 0.0072 15.9 6.0 0.0072 15.9 4.1 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KUM60037.1 - 0.0083 16.1 6.2 0.0083 16.1 4.3 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KUM60037.1 - 0.023 14.6 4.8 0.023 14.6 3.3 2.2 2 1 0 2 2 2 0 FANCL C-terminal domain zf-Apc11 PF12861.2 KUM60037.1 - 0.049 13.4 5.4 0.17 11.7 1.9 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 KUM60037.1 - 0.14 12.2 6.2 0.46 10.5 4.3 1.9 1 0 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.1 KUM60037.1 - 8.6 6.1 10.2 4.5 7.0 2.9 2.6 2 0 0 2 2 2 0 RING-type zinc-finger Zn_clus PF00172.13 KUM60038.1 - 2.7e-05 24.0 13.1 4.2e-05 23.3 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KUM60038.1 - 9.6e-05 21.3 0.0 0.0002 20.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_4 PF01565.18 KUM60039.1 - 7.9e-25 86.9 0.7 1.7e-24 85.8 0.5 1.6 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_11 PF00457.12 KUM60039.1 - 0.065 12.5 0.7 0.17 11.2 0.2 1.9 2 0 0 2 2 2 0 Glycosyl hydrolases family 11 MARVEL PF01284.18 KUM60040.1 - 0.31 10.8 15.3 0.49 10.2 10.6 1.3 1 0 0 1 1 1 0 Membrane-associating domain ThiS PF02597.15 KUM60041.1 - 3.5e-12 46.5 0.0 3.8e-12 46.4 0.0 1.0 1 0 0 1 1 1 1 ThiS family Cys_Met_Meta_PP PF01053.15 KUM60042.1 - 9.8e-61 205.1 0.0 2.1e-60 204.0 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KUM60042.1 - 0.024 13.3 0.0 0.043 12.5 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V Aminotran_1_2 PF00155.16 KUM60042.1 - 0.085 11.7 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KUM60042.1 - 0.1 11.6 0.0 10 5.0 0.0 2.5 3 0 0 3 3 3 0 DegT/DnrJ/EryC1/StrS aminotransferase family p450 PF00067.17 KUM60043.1 - 8.6e-56 189.3 0.0 1.2e-55 188.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 KUM60044.1 - 1.3e-47 162.1 0.0 1.8e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KUM60044.1 - 8.3e-28 97.1 0.0 1.5e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KUM60044.1 - 3.2e-21 75.9 0.0 1.7e-20 73.5 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KUM60044.1 - 0.061 13.2 0.0 0.85 9.5 0.0 2.7 3 0 0 3 3 3 0 Ferric reductase NAD binding domain SSFA2_C PF14723.1 KUM60045.1 - 0.0038 16.9 0.9 0.15 11.8 0.3 2.7 2 0 0 2 2 2 2 Sperm-specific antigen 2 C-terminus RTC PF01137.16 KUM60046.1 - 1.1e-35 122.4 0.0 1.8e-35 121.7 0.0 1.4 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Exo_endo_phos PF03372.18 KUM60048.1 - 7.4e-17 62.1 1.6 1e-16 61.6 1.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ADH_zinc_N PF00107.21 KUM60049.1 - 1.2e-20 73.3 0.0 2e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM60049.1 - 1.6e-19 69.6 0.8 3e-19 68.7 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain mono-CXXC PF15626.1 KUM60049.1 - 0.61 10.0 4.4 1.1 9.1 3.0 1.4 1 0 0 1 1 1 0 single CXXC unit Aldedh PF00171.17 KUM60050.1 - 4.5e-95 318.6 0.0 5e-95 318.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KUM60050.1 - 0.1 11.3 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Fungal_trans PF04082.13 KUM60052.1 - 1.1e-13 50.7 1.4 1.2e-13 50.5 0.3 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM60052.1 - 8.6e-06 25.5 6.7 8.6e-06 25.5 4.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 KUM60052.1 - 0.0008 19.6 10.6 0.028 14.7 0.8 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KUM60052.1 - 0.0083 16.3 1.9 0.0083 16.3 1.3 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KUM60052.1 - 0.025 14.8 9.0 0.034 14.4 0.3 3.6 3 0 0 3 3 3 0 Zinc-finger double domain Carboxyl_trans PF01039.17 KUM60054.1 - 2.8e-78 263.4 0.0 3.6e-78 263.1 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain CAP59_mtransfer PF11735.3 KUM60055.1 - 7.7e-75 251.2 0.0 9.5e-75 250.9 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 S-methyl_trans PF02574.11 KUM60056.1 - 6.1e-27 94.7 0.0 8.1e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Cytochrom_C_2 PF01322.15 KUM60056.1 - 0.071 13.6 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Cytochrome C' Macro PF01661.16 KUM60057.1 - 1.8e-30 105.2 0.0 2.6e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Macro domain Lar_restr_allev PF14354.1 KUM60057.1 - 0.0025 18.1 0.1 0.006 16.8 0.0 1.6 1 0 0 1 1 1 1 Restriction alleviation protein Lar HPP PF04982.8 KUM60058.1 - 5.8e-42 142.3 6.8 9.2e-42 141.6 4.7 1.3 1 0 0 1 1 1 1 HPP family Tmemb_14 PF03647.8 KUM60058.1 - 0.75 10.2 5.1 8 6.9 3.5 2.4 1 1 0 1 1 1 0 Transmembrane proteins 14C DUF3792 PF12670.2 KUM60058.1 - 2.6 7.9 7.0 0.24 11.2 1.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) AA_permease PF00324.16 KUM60060.1 - 3.7e-111 371.8 43.0 4.4e-111 371.5 29.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KUM60060.1 - 5.9e-40 137.0 49.4 7.3e-40 136.7 34.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2422 PF10337.4 KUM60061.1 - 1.8e-121 406.1 0.4 1.3e-117 393.4 0.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 KUM60061.1 - 3.3e-61 206.8 0.0 2.1e-60 204.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 KUM60061.1 - 2.1e-10 40.6 13.8 2.1e-10 40.6 9.6 3.5 3 1 0 3 3 3 1 Fusaric acid resistance protein-like Mitofilin PF09731.4 KUM60061.1 - 0.0041 15.8 1.2 0.0074 15.0 0.8 1.3 1 0 0 1 1 1 1 Mitochondrial inner membrane protein ALMT PF11744.3 KUM60061.1 - 5 5.6 5.3 1 7.9 0.8 1.9 2 0 0 2 2 2 0 Aluminium activated malate transporter CPSase_L_D2 PF02786.12 KUM60062.1 - 1.8e-58 197.3 0.0 2.6e-58 196.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 KUM60062.1 - 5.1e-32 110.0 0.0 9.6e-32 109.1 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 KUM60062.1 - 7.9e-26 90.3 0.0 1.5e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 KUM60062.1 - 1.1e-18 67.6 0.1 2.1e-18 66.7 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KUM60062.1 - 2.2e-13 49.6 0.0 3e-08 32.7 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 KUM60062.1 - 4.6e-11 42.1 0.2 1.3e-10 40.7 0.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 KUM60062.1 - 8.5e-11 41.6 0.0 2.1e-10 40.3 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KUM60062.1 - 9.6e-07 28.3 0.1 2.1e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KUM60062.1 - 1.5e-05 24.9 0.0 3.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KUM60062.1 - 0.00032 20.2 0.0 0.0058 16.1 0.0 2.3 2 0 0 2 2 2 1 RimK-like ATP-grasp domain RnfC_N PF13375.1 KUM60062.1 - 0.00088 18.9 0.0 0.0025 17.5 0.0 1.7 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.1 KUM60062.1 - 0.0033 17.0 0.1 0.015 14.9 0.0 2.0 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_2 PF12700.2 KUM60062.1 - 0.063 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 HlyD family secretion protein DUF2118 PF09891.4 KUM60062.1 - 0.08 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) ATP-grasp_5 PF13549.1 KUM60062.1 - 0.092 11.9 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.1 KUM60062.1 - 0.18 10.8 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp MFS_1 PF07690.11 KUM60063.1 - 1.9e-15 56.4 41.6 1.1e-13 50.6 26.9 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM60063.1 - 0.0027 16.3 7.4 0.0027 16.3 5.2 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter RTA1 PF04479.8 KUM60064.1 - 7.1e-51 172.8 2.8 8.7e-51 172.5 2.0 1.0 1 0 0 1 1 1 1 RTA1 like protein Ninjurin PF04923.7 KUM60064.1 - 0.47 10.1 4.6 1.1 9.0 1.4 2.7 1 1 1 2 2 2 0 Ninjurin Methyltransf_11 PF08241.7 KUM60066.1 - 0.041 14.3 0.0 0.1 13.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain ATP-synt_DE PF00401.15 KUM60066.1 - 0.22 11.4 0.8 0.59 10.0 0.6 1.6 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain MFS_1 PF07690.11 KUM60068.1 - 4.7e-48 163.7 33.7 4.7e-48 163.7 23.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM60068.1 - 2.2e-17 62.7 4.5 2.2e-17 62.7 3.1 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.15 KUM60068.1 - 0.0006 17.9 3.0 0.058 11.4 1.7 3.0 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 KUM60068.1 - 0.0035 15.5 5.9 0.0052 14.9 4.1 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector p450 PF00067.17 KUM60069.1 - 7.5e-72 242.3 0.0 8.5e-72 242.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 P30 PF07390.6 KUM60070.1 - 0.1 12.0 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Mycoplasma P30 protein Annexin PF00191.15 KUM60071.1 - 6.2e-63 208.6 0.7 1.3e-18 66.5 0.0 4.2 4 0 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.1 KUM60071.1 - 0.29 11.3 1.1 14 5.9 0.0 3.1 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 GCS PF03074.11 KUM60074.1 - 0.13 11.2 0.7 0.21 10.6 0.5 1.2 1 0 0 1 1 1 0 Glutamate-cysteine ligase SAP PF02037.22 KUM60075.1 - 4.5e-10 38.7 0.6 1.3e-09 37.3 0.0 2.1 2 0 0 2 2 2 1 SAP domain PorB PF11565.3 KUM60075.1 - 0.038 14.2 0.1 0.092 12.9 0.1 1.7 1 0 0 1 1 1 0 Alpha helical Porin B Creatinase_N PF01321.13 KUM60075.1 - 0.082 13.3 0.2 2 8.9 0.0 2.2 2 0 0 2 2 2 0 Creatinase/Prolidase N-terminal domain Usp PF00582.21 KUM60075.1 - 5 7.3 5.9 0.67 10.1 0.3 2.2 2 1 0 2 2 2 0 Universal stress protein family ABC2_membrane PF01061.19 KUM60076.1 - 2.4e-89 298.0 56.8 1.7e-51 174.3 17.0 3.1 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 KUM60076.1 - 1.1e-41 140.6 5.8 1.5e-35 120.9 0.0 3.8 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 KUM60076.1 - 8.2e-40 136.2 0.0 1.7e-19 70.4 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 KUM60076.1 - 3.7e-17 62.1 0.2 1.4e-16 60.3 0.1 2.1 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KUM60076.1 - 1.2e-06 28.0 0.4 0.0011 18.4 0.2 2.8 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KUM60076.1 - 5.4e-06 26.5 1.0 0.001 19.0 0.1 2.8 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 KUM60076.1 - 1.3e-05 24.4 0.1 0.0023 17.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC2_membrane_3 PF12698.2 KUM60076.1 - 0.00011 21.3 19.2 0.00011 21.3 13.3 3.1 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.1 KUM60076.1 - 0.00012 21.5 1.8 0.0085 15.6 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 KUM60076.1 - 0.00015 21.6 0.0 0.014 15.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KUM60076.1 - 0.00034 20.0 0.2 0.019 14.4 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 KUM60076.1 - 0.00098 19.4 0.0 0.097 12.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KUM60076.1 - 0.0014 18.6 1.7 2.8 7.8 0.0 3.7 5 0 0 5 5 4 2 AAA domain AAA_17 PF13207.1 KUM60076.1 - 0.0023 18.7 0.0 0.62 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KUM60076.1 - 0.0045 17.1 0.1 2.3 8.3 0.0 3.1 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KUM60076.1 - 0.0052 16.0 0.0 0.25 10.5 0.0 3.0 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.7 KUM60076.1 - 0.018 14.7 2.3 3.3 7.3 0.2 3.1 3 0 0 3 3 3 0 NACHT domain T2SE PF00437.15 KUM60076.1 - 0.019 13.8 0.2 0.44 9.3 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.1 KUM60076.1 - 0.024 14.3 1.3 6.4 6.5 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA PF00004.24 KUM60076.1 - 0.097 12.8 0.1 24 5.1 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 KUM60076.1 - 0.2 12.1 0.0 22 5.5 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_10 PF12846.2 KUM60076.1 - 0.49 9.7 2.6 16 4.7 0.1 3.4 4 0 0 4 4 4 0 AAA-like domain Zn_clus PF00172.13 KUM60077.1 - 8.9e-10 38.3 10.6 1.8e-09 37.3 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KUM60077.1 - 1.2e-06 27.3 0.1 1.6e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3630 PF12305.3 KUM60077.1 - 0.089 12.6 0.2 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3630) DUF4011 PF13195.1 KUM60078.1 - 0.14 12.1 0.2 3.3e+02 1.1 0.0 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF4011) F-box-like PF12937.2 KUM60081.1 - 0.00088 18.9 0.1 0.0017 18.0 0.1 1.5 1 0 0 1 1 1 1 F-box-like DUF2752 PF10825.3 KUM60082.1 - 0.1 12.6 4.1 0.16 11.9 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) Adaptin_binding PF10199.4 KUM60082.1 - 0.32 11.2 10.3 0.062 13.5 4.1 2.1 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Dicty_REP PF05086.7 KUM60082.1 - 1.1 6.9 4.0 1.8 6.2 2.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Abhydrolase_6 PF12697.2 KUM60083.1 - 5.4e-13 49.3 0.6 1e-12 48.4 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM60083.1 - 7.8e-12 45.1 0.1 1.3e-11 44.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KUM60083.1 - 5.7e-06 26.0 0.0 9.5e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KUM60083.1 - 0.0091 15.4 0.2 0.1 12.0 0.0 2.4 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KUM60083.1 - 0.012 14.8 0.1 0.12 11.5 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KUM60083.1 - 0.015 14.8 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KUM60083.1 - 0.034 13.9 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase AXE1 PF05448.7 KUM60083.1 - 0.065 11.7 0.1 0.12 10.8 0.0 1.6 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Epimerase PF01370.16 KUM60085.1 - 2e-47 161.6 0.1 2.3e-47 161.3 0.1 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KUM60085.1 - 1.4e-17 63.2 0.0 1.9e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KUM60085.1 - 2.5e-17 62.6 0.0 6.2e-17 61.4 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KUM60085.1 - 9.7e-08 31.2 0.0 9.9e-05 21.3 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 KUM60085.1 - 8.8e-06 24.8 0.0 5.1e-05 22.3 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KUM60085.1 - 4.8e-05 23.4 0.1 0.00027 20.9 0.0 2.1 2 1 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 KUM60085.1 - 0.00033 20.6 0.1 0.0026 17.7 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM60085.1 - 0.012 15.3 0.1 0.093 12.3 0.0 2.2 1 1 0 1 1 1 0 KR domain DapB_N PF01113.15 KUM60085.1 - 0.07 13.0 0.0 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus ThiF PF00899.16 KUM60085.1 - 0.079 12.7 0.3 0.45 10.3 0.1 2.0 2 0 0 2 2 2 0 ThiF family AMP-binding PF00501.23 KUM60087.1 - 9.8e-173 574.3 2.0 3.1e-96 322.3 0.1 2.4 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KUM60087.1 - 8.4e-81 271.1 0.1 9.1e-37 126.5 0.1 3.3 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.20 KUM60087.1 - 2.1e-17 63.1 0.0 1.2e-09 38.3 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KUM60087.1 - 2.5e-17 63.5 0.1 1.4e-08 35.5 0.0 3.1 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain ADH_N PF08240.7 KUM60089.1 - 8.7e-06 25.4 0.0 2.2e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM60089.1 - 0.005 16.3 0.1 0.0086 15.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KUM60089.1 - 0.009 16.9 0.0 0.02 15.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NmrA PF05368.8 KUM60089.1 - 0.083 12.1 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family MFS_1 PF07690.11 KUM60090.1 - 1.2e-28 99.9 61.3 6e-28 97.5 37.1 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily ABC_tran PF00005.22 KUM60091.1 - 4.2e-43 146.9 0.1 1.4e-21 77.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KUM60091.1 - 9.4e-23 80.9 13.8 9.4e-23 80.9 9.5 2.2 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA_21 PF13304.1 KUM60091.1 - 1.4e-14 54.7 0.0 0.0042 17.0 0.0 4.4 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 KUM60091.1 - 1.1e-10 41.1 4.4 0.0091 15.2 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain T2SE PF00437.15 KUM60091.1 - 2.9e-06 26.4 0.9 0.0077 15.1 0.6 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 KUM60091.1 - 7.8e-06 25.9 1.4 0.0012 18.8 0.2 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KUM60091.1 - 1.2e-05 26.1 0.3 0.026 15.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KUM60091.1 - 2.3e-05 23.9 0.5 0.33 10.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 KUM60091.1 - 2.9e-05 24.2 3.3 0.015 15.4 0.2 3.2 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KUM60091.1 - 6e-05 22.4 2.6 0.25 10.9 0.4 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KUM60091.1 - 0.0001 21.5 0.6 0.043 13.0 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 KUM60091.1 - 0.00017 21.9 0.7 0.036 14.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KUM60091.1 - 0.0002 20.4 0.7 0.54 9.3 0.1 2.6 3 0 0 3 3 2 2 Zeta toxin AAA_33 PF13671.1 KUM60091.1 - 0.00022 21.1 0.1 0.013 15.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 KUM60091.1 - 0.00022 21.0 4.1 0.022 14.6 0.0 3.3 3 1 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 KUM60091.1 - 0.00023 20.7 1.6 0.065 12.6 0.2 2.6 2 0 0 2 2 2 1 AAA-like domain FtsK_SpoIIIE PF01580.13 KUM60091.1 - 0.00048 19.6 0.6 0.33 10.3 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 KUM60091.1 - 0.00098 19.0 0.2 1.1 9.2 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 KUM60091.1 - 0.0012 19.2 1.0 0.69 10.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain Miro PF08477.8 KUM60091.1 - 0.0029 18.0 1.6 1.9 8.9 0.1 2.6 2 0 0 2 2 2 1 Miro-like protein Arch_ATPase PF01637.13 KUM60091.1 - 0.004 16.8 0.1 0.046 13.4 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase MobB PF03205.9 KUM60091.1 - 0.005 16.5 2.8 0.17 11.5 0.4 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 KUM60091.1 - 0.0054 16.4 1.2 0.017 14.8 0.3 2.2 2 0 0 2 2 2 1 Part of AAA domain UPF0079 PF02367.12 KUM60091.1 - 0.0054 16.3 0.9 0.032 13.8 0.2 2.2 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Dynamin_N PF00350.18 KUM60091.1 - 0.0095 15.7 0.3 0.34 10.7 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA PF00004.24 KUM60091.1 - 0.01 16.0 1.7 0.095 12.9 0.0 3.2 5 0 0 5 5 3 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KUM60091.1 - 0.016 14.9 2.2 0.04 13.5 0.3 2.3 2 0 0 2 2 2 0 NACHT domain GTP_EFTU PF00009.22 KUM60091.1 - 0.017 14.5 0.4 0.41 10.0 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain IstB_IS21 PF01695.12 KUM60091.1 - 0.029 13.8 0.1 11 5.4 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein PduV-EutP PF10662.4 KUM60091.1 - 0.034 13.6 1.8 0.36 10.3 0.2 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 KUM60091.1 - 0.035 13.5 5.4 0.035 13.5 1.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 KUM60091.1 - 0.053 13.4 0.2 0.38 10.6 0.0 2.6 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 KUM60091.1 - 0.054 13.6 1.0 11 6.2 0.1 3.2 2 1 1 3 3 3 0 RNA helicase DEAD PF00270.24 KUM60091.1 - 0.075 12.5 0.4 19 4.6 0.2 2.9 2 1 0 2 2 2 0 DEAD/DEAH box helicase ATP_bind_1 PF03029.12 KUM60091.1 - 0.1 12.1 1.7 2.1 7.7 0.1 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 KUM60091.1 - 0.21 11.1 1.7 1.3 8.5 0.4 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KUM60091.1 - 0.42 10.3 2.5 4.6 6.9 0.2 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 KUM60091.1 - 0.53 9.9 3.1 2.8 7.6 0.4 2.6 2 0 0 2 2 2 0 NTPase DUF87 PF01935.12 KUM60091.1 - 0.55 10.0 4.4 1.5 8.6 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_30 PF13604.1 KUM60091.1 - 0.59 9.6 2.2 1.1 8.8 0.2 2.1 2 1 0 2 2 2 0 AAA domain Fungal_trans PF04082.13 KUM60092.1 - 7.7e-29 100.3 0.4 1.2e-28 99.6 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM60092.1 - 3.8e-08 33.1 8.9 9.3e-08 31.8 6.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.17 KUM60093.1 - 1e-25 89.1 0.5 3.8e-14 52.0 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM60093.1 - 5.6e-24 83.9 0.0 1.1e-12 47.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM60093.1 - 1.6e-07 31.0 0.1 0.00072 19.3 0.1 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.5 KUM60094.1 - 1.1e-30 106.3 4.1 1.1e-30 106.3 2.8 2.0 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding I-set PF07679.11 KUM60095.1 - 8.6e-07 28.7 0.1 0.021 14.6 0.0 4.7 4 0 0 4 4 4 3 Immunoglobulin I-set domain SWM_repeat PF13753.1 KUM60095.1 - 0.00021 20.4 0.0 0.019 14.0 0.0 2.5 2 0 0 2 2 2 2 Putative flagellar system-associated repeat Peptidase_C12 PF01088.16 KUM60096.1 - 4e-62 209.1 0.1 9e-62 208.0 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 ZZ PF00569.12 KUM60097.1 - 1.2e-20 72.7 54.8 3.4e-07 29.6 2.7 4.5 4 0 0 4 4 4 4 Zinc finger, ZZ type Arylesterase PF01731.15 KUM60098.1 - 0.004 17.0 0.1 0.02 14.8 0.0 2.4 2 1 0 2 2 2 1 Arylesterase Pkinase PF00069.20 KUM60099.1 - 1.3e-41 142.4 0.0 1.3e-18 67.0 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KUM60099.1 - 2.4e-09 36.6 0.0 0.00023 20.3 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KUM60099.1 - 0.00036 20.3 0.1 0.79 9.4 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KUM60099.1 - 0.011 14.7 0.0 0.92 8.4 0.0 2.3 2 0 0 2 2 2 0 Kinase-like OTU PF02338.14 KUM60100.1 - 1.1e-12 48.5 0.0 1.9e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KUM60100.1 - 0.01 15.1 0.0 0.039 13.3 0.0 1.8 1 1 1 2 2 2 0 Peptidase C65 Otubain Oxysterol_BP PF01237.13 KUM60101.1 - 3.3e-54 183.7 0.0 9e-54 182.2 0.0 1.7 1 1 0 1 1 1 1 Oxysterol-binding protein Cnd1_N PF12922.2 KUM60102.1 - 3.9e-58 195.8 0.0 9.8e-58 194.5 0.0 1.7 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 KUM60102.1 - 5.5e-46 156.6 9.5 1e-41 142.7 1.9 3.2 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KUM60102.1 - 6.8e-13 48.7 2.8 1.2e-06 28.7 0.0 4.5 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 KUM60102.1 - 4.8e-08 32.4 10.7 0.19 11.8 0.0 6.5 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 KUM60102.1 - 2.9e-07 30.7 8.2 0.042 14.3 0.1 6.0 6 0 0 6 6 6 3 HEAT-like repeat Adaptin_N PF01602.15 KUM60102.1 - 5.5e-06 24.9 9.4 0.0071 14.7 0.4 4.1 3 2 0 3 3 3 2 Adaptin N terminal region DUF2435 PF10363.4 KUM60102.1 - 0.004 17.0 0.0 1.5 8.8 0.0 3.7 2 1 1 3 3 3 1 Protein of unknown function (DUF2435) FlbD PF06289.6 KUM60102.1 - 0.13 11.6 0.0 0.31 10.4 0.0 1.6 1 0 0 1 1 1 0 Flagellar protein (FlbD) Cnd3 PF12719.2 KUM60102.1 - 0.93 8.4 11.5 0.11 11.4 1.9 3.4 3 2 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain MFS_1 PF07690.11 KUM60103.1 - 1.1e-21 76.9 32.8 1.1e-21 76.9 22.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KUM60103.1 - 8e-08 31.0 18.7 1e-07 30.7 11.5 2.0 1 1 0 1 1 1 1 MFS/sugar transport protein ATG22 PF11700.3 KUM60103.1 - 1.8 6.9 21.4 7.6 4.8 14.2 2.3 1 1 0 1 1 1 0 Vacuole effluxer Atg22 like HTH_Tnp_Tc5 PF03221.11 KUM60104.1 - 0.014 15.1 0.2 0.028 14.2 0.1 1.5 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain BIR PF00653.16 KUM60104.1 - 0.027 14.8 5.9 5.1 7.6 0.1 3.5 2 1 0 2 2 2 0 Inhibitor of Apoptosis domain zf-C2H2 PF00096.21 KUM60104.1 - 0.057 13.7 17.1 0.13 12.7 1.8 4.2 3 2 1 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KUM60104.1 - 1.3 9.5 18.6 12 6.5 5.2 4.4 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KUM60104.1 - 2.6 8.1 7.0 29 4.8 1.4 2.9 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) COesterase PF00135.23 KUM60105.1 - 9.5e-59 199.5 0.0 1.3e-58 199.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KUM60105.1 - 0.12 11.9 0.0 0.6 9.6 0.0 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold Pyr_redox_3 PF13738.1 KUM60106.1 - 2.3e-22 80.0 0.0 4.2e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KUM60106.1 - 2.2e-15 55.8 3.4 5.1e-14 51.3 0.3 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KUM60106.1 - 4.2e-10 39.5 0.0 8.7e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KUM60106.1 - 5.1e-10 38.7 0.2 2e-07 30.2 0.1 3.1 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KUM60106.1 - 1.8e-08 34.5 0.0 7.7e-08 32.4 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM60106.1 - 1.5e-05 24.8 0.2 0.0013 18.4 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 KUM60106.1 - 2.2e-05 23.5 0.0 0.009 14.9 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KUM60106.1 - 0.0032 16.4 0.0 0.0064 15.4 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 KUM60106.1 - 0.0072 15.4 0.0 0.21 10.6 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Ino80_Iec3 PF14612.1 KUM60107.1 - 1.2e-85 287.3 3.2 1.9e-85 286.6 2.2 1.3 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling FAD_binding_3 PF01494.14 KUM60108.1 - 5.5e-77 259.2 0.0 1.5e-76 257.7 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KUM60108.1 - 2.1e-21 76.2 0.0 3.9e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.9 KUM60108.1 - 0.0081 16.0 0.0 0.12 12.2 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KUM60108.1 - 0.017 14.0 0.2 0.91 8.3 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase SE PF08491.5 KUM60108.1 - 0.025 13.4 0.0 0.098 11.4 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase HI0933_like PF03486.9 KUM60108.1 - 0.034 12.6 0.0 0.18 10.2 0.0 2.0 3 0 0 3 3 3 0 HI0933-like protein Lycopene_cycl PF05834.7 KUM60108.1 - 0.11 11.3 0.1 0.18 10.7 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Bromodomain PF00439.20 KUM60109.1 - 3.1e-37 126.3 4.2 1.1e-18 66.9 0.2 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 KUM60109.1 - 1.8e-17 63.2 1.0 3.6e-17 62.2 0.7 1.6 1 0 0 1 1 1 1 BAH domain Nucleoplasmin PF03066.10 KUM60109.1 - 0.021 14.3 5.4 0.037 13.5 3.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin EBV-NA3 PF05009.7 KUM60109.1 - 0.034 13.4 1.2 0.067 12.4 0.8 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) CENP-B_dimeris PF09026.5 KUM60109.1 - 4.7 7.5 11.9 3.6 7.8 6.6 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Zn_clus PF00172.13 KUM60110.1 - 4.4e-07 29.6 6.4 4.4e-07 29.6 4.4 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_4 PF01063.14 KUM60111.1 - 5.4e-26 91.4 0.0 7.1e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV ECR1_N PF14382.1 KUM60112.1 - 1.3e-10 40.3 0.0 3e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 KUM60112.1 - 0.0008 19.3 0.1 0.014 15.3 0.1 2.4 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 IFRD PF05004.8 KUM60113.1 - 2.1e-34 119.0 0.2 2.8e-34 118.5 0.1 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.1 KUM60113.1 - 0.00051 20.2 0.1 0.24 11.7 0.1 3.2 1 1 1 2 2 2 2 HEAT repeats Cnd3 PF12719.2 KUM60113.1 - 0.0012 17.9 0.1 0.0036 16.3 0.0 1.8 1 1 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.17 KUM60113.1 - 0.0032 17.4 2.6 0.74 10.0 0.0 4.3 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 KUM60113.1 - 0.023 15.1 0.2 29 5.3 0.0 4.0 3 1 1 4 4 4 0 HEAT-like repeat Sigma70_ner PF04546.8 KUM60113.1 - 0.12 12.0 8.3 1.6 8.2 2.4 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region Nop53 PF07767.6 KUM60113.1 - 1.5 7.7 10.6 3 6.7 4.2 2.7 2 1 1 3 3 3 0 Nop53 (60S ribosomal biogenesis) DUF789 PF05623.7 KUM60113.1 - 9.3 5.6 10.5 0.69 9.3 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF789) PDH PF02153.12 KUM60114.1 - 6.2e-11 41.6 0.0 8.5e-11 41.2 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 KUM60114.1 - 8.2e-07 28.9 0.0 2.5e-06 27.4 0.0 2.0 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KUM60114.1 - 2.4e-06 27.8 0.0 4.8e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 KUM60114.1 - 0.00031 20.1 0.0 0.00075 18.9 0.0 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 KUM60114.1 - 0.00063 18.9 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KUM60114.1 - 0.0067 16.0 0.0 0.018 14.6 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.7 KUM60114.1 - 0.06 12.7 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 KUM60114.1 - 0.072 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Abhydrolase_3 PF07859.8 KUM60115.1 - 1.3e-41 142.4 0.0 1.7e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 KUM60115.1 - 2.7e-05 23.5 0.0 5.8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KUM60115.1 - 0.00046 19.9 0.0 0.00083 19.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KUM60115.1 - 0.0038 16.0 0.1 0.029 13.1 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family DUF2424 PF10340.4 KUM60115.1 - 0.038 12.6 0.0 0.06 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Fungal_trans PF04082.13 KUM60116.1 - 6.2e-11 41.6 1.6 9.3e-11 41.0 1.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM60116.1 - 0.018 14.9 2.4 0.039 13.8 1.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 KUM60117.1 - 1e-19 70.8 0.0 2.1e-19 69.8 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KUM60117.1 - 1.6e-06 27.2 0.2 0.00047 19.1 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KUM60117.1 - 0.0015 17.5 0.4 0.0045 15.9 0.3 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KUM60117.1 - 0.0056 16.6 0.5 0.013 15.5 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KUM60117.1 - 0.03 13.1 2.5 0.047 12.5 1.8 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 KUM60117.1 - 0.13 12.2 0.8 0.32 11.0 0.5 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KUM60117.1 - 0.19 10.7 0.7 3.3 6.6 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase DEC-1_N PF04625.8 KUM60118.1 - 0.021 13.5 2.8 0.029 13.0 1.9 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region AATase PF07247.7 KUM60118.1 - 0.24 9.9 0.1 0.93 7.9 0.0 1.8 1 1 0 1 1 1 0 Alcohol acetyltransferase Ribosomal_S11 PF00411.14 KUM60119.1 - 2e-40 137.3 0.4 2.6e-40 137.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 RICTOR_N PF14664.1 KUM60120.1 - 2.6e-133 444.2 1.4 4.8e-133 443.3 1.0 1.5 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 KUM60120.1 - 8.1e-88 293.2 0.2 1.1e-85 286.2 0.2 3.2 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 KUM60120.1 - 2.5e-43 146.6 0.0 9.4e-42 141.5 0.0 2.8 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 KUM60120.1 - 1.8e-24 85.4 2.1 6.8e-24 83.5 0.2 3.0 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 KUM60120.1 - 1.1e-11 44.2 3.6 2.3e-11 43.2 2.5 1.5 1 0 0 1 1 1 1 Hr1 repeat Uds1 PF15456.1 KUM60120.1 - 0.011 15.7 4.4 0.027 14.4 3.1 1.6 1 0 0 1 1 1 0 Up-regulated During Septation FAA_hydrolase_N PF09298.6 KUM60120.1 - 0.13 12.2 1.4 0.52 10.3 1.0 2.0 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal NAD_binding_4 PF07993.7 KUM60121.1 - 1.1e-36 126.0 0.0 2.7e-36 124.7 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 KUM60121.1 - 1.9e-29 102.2 0.0 1.1e-28 99.8 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.16 KUM60121.1 - 4.1e-09 36.2 0.0 6.9e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KUM60121.1 - 1.6e-05 25.1 0.0 4.5e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Aminotran_4 PF01063.14 KUM60122.1 - 3.1e-23 82.4 0.0 6.4e-23 81.4 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class IV AAR2 PF05282.6 KUM60123.1 - 9.2e-93 311.0 0.0 1.1e-92 310.7 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein IgaA PF07095.6 KUM60124.1 - 0.16 9.7 0.0 0.22 9.2 0.0 1.1 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA DUF2834 PF11196.3 KUM60124.1 - 0.83 9.8 6.6 0.11 12.7 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2834) MFS_1 PF07690.11 KUM60125.1 - 1.1e-33 116.3 42.0 1.7e-33 115.7 29.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily FWWh PF14922.1 KUM60125.1 - 1.6 8.2 4.7 4.1 6.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function Abhydrolase_6 PF12697.2 KUM60126.1 - 1.5e-11 44.6 0.0 2.5e-11 43.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM60126.1 - 0.00064 19.4 0.0 0.0015 18.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Fungal_trans PF04082.13 KUM60128.1 - 4.4e-20 71.6 0.1 6.9e-20 71.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM60128.1 - 5.7e-05 22.9 9.2 0.00011 22.0 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Paf67 PF10255.4 KUM60129.1 - 1.5e-155 518.0 0.0 1.7e-155 517.8 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_12 PF13424.1 KUM60129.1 - 0.042 13.7 1.5 8.7 6.3 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 KUM60129.1 - 0.063 13.2 0.0 0.44 10.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Adaptin_N PF01602.15 KUM60130.1 - 1.1e-127 426.5 7.1 1.3e-127 426.3 4.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KUM60130.1 - 3.4e-16 59.6 5.1 4.1e-16 59.3 0.3 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KUM60130.1 - 1.4e-15 57.3 1.2 8.1e-09 35.6 0.0 4.5 2 2 3 5 5 5 3 HEAT repeats HEAT PF02985.17 KUM60130.1 - 5.7e-10 38.4 5.6 0.0015 18.4 0.0 6.1 8 0 0 8 8 8 3 HEAT repeat Atx10homo_assoc PF09759.4 KUM60130.1 - 1.8e-07 30.8 0.1 0.72 9.6 0.0 3.8 3 0 0 3 3 3 3 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.1 KUM60130.1 - 1.3e-05 25.5 2.3 6 7.5 0.0 6.2 6 0 0 6 6 6 2 HEAT-like repeat CLASP_N PF12348.3 KUM60130.1 - 0.0019 17.6 0.2 2.6 7.3 0.0 3.3 3 0 0 3 3 3 2 CLASP N terminal Arm PF00514.18 KUM60130.1 - 0.17 11.7 6.1 3.4 7.6 0.0 4.9 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DUF1077 PF06417.7 KUM60131.1 - 9e-52 173.7 2.5 1.2e-51 173.3 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) TMEM171 PF15471.1 KUM60131.1 - 0.12 11.1 0.8 0.16 10.7 0.5 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 Rubella_Capsid PF05750.6 KUM60131.1 - 5.8 6.2 9.6 9.6 5.4 6.6 1.3 1 0 0 1 1 1 0 Rubella capsid protein MFS_1 PF07690.11 KUM60132.1 - 1.6e-54 184.9 19.3 1.6e-54 184.9 13.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM60132.1 - 9.3e-13 47.5 19.6 1.9e-12 46.5 7.4 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter DUF791 PF05631.9 KUM60132.1 - 0.00052 18.8 3.7 0.0012 17.6 2.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF791) Fe-S_biosyn PF01521.15 KUM60133.1 - 3.4e-09 36.6 0.0 9.5e-09 35.1 0.0 1.7 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Aminotran_5 PF00266.14 KUM60134.1 - 4.7e-13 48.6 0.0 1.9e-12 46.6 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KUM60134.1 - 0.0091 14.3 0.0 0.023 13.0 0.0 1.5 1 1 1 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KUM60134.1 - 0.013 14.5 0.1 0.022 13.8 0.1 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.15 KUM60134.1 - 0.018 13.6 0.2 0.04 12.4 0.2 1.5 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Cleaved_Adhesin PF07675.6 KUM60134.1 - 0.066 12.8 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Cleaved Adhesin Domain Fungal_trans_2 PF11951.3 KUM60136.1 - 8.7e-09 34.4 1.8 8.3e-07 27.9 0.2 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain dUTPase PF00692.14 KUM60137.1 - 2.3e-11 43.2 0.1 4e-11 42.4 0.0 1.4 2 0 0 2 2 2 1 dUTPase AMP-binding PF00501.23 KUM60138.1 - 1e-82 277.8 0.0 1.2e-82 277.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KUM60138.1 - 6e-11 43.1 0.0 2.5e-10 41.1 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 KUM60139.1 - 4.7e-56 190.0 26.9 1.4e-49 168.7 9.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 KUM60139.1 - 2.2e-07 29.3 14.4 9.2e-07 27.3 5.6 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector ATG22 PF11700.3 KUM60139.1 - 0.024 13.1 20.5 0.25 9.7 8.8 2.9 2 1 0 2 2 2 0 Vacuole effluxer Atg22 like OATP PF03137.15 KUM60139.1 - 0.082 10.9 0.3 7.4 4.4 0.0 2.7 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family COesterase PF00135.23 KUM60140.1 - 2.5e-60 204.6 0.0 4e-53 180.9 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KUM60140.1 - 0.00047 19.7 0.0 0.00089 18.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold HgmA PF04209.8 KUM60141.1 - 5.6e-151 502.7 0.1 6.5e-151 502.5 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase TPR_11 PF13414.1 KUM60143.1 - 9.5e-14 50.7 1.4 3.3e-13 49.0 0.3 2.2 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 KUM60143.1 - 2e-06 27.6 0.4 6.4e-06 26.0 0.2 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 KUM60143.1 - 3.1e-06 26.5 0.7 0.057 13.0 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KUM60143.1 - 2.6e-05 23.7 0.7 0.16 11.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KUM60143.1 - 0.0017 18.4 0.3 0.0044 17.1 0.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KUM60143.1 - 0.0023 17.6 2.8 2 8.4 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KUM60143.1 - 0.0041 17.7 2.9 0.042 14.5 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF1179 PF06678.6 KUM60143.1 - 0.052 13.8 1.0 0.099 12.9 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) TPR_19 PF14559.1 KUM60143.1 - 0.092 13.0 4.2 2.7 8.4 0.0 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat Rib_5-P_isom_A PF06026.9 KUM60144.1 - 2e-39 134.6 0.1 1.4e-37 128.6 0.0 2.1 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 KUM60144.1 - 0.0017 17.9 0.1 1.1 8.9 0.0 2.2 2 0 0 2 2 2 2 DeoR C terminal sensor domain ATP_bind_1 PF03029.12 KUM60146.1 - 2.1e-76 256.5 0.0 2.7e-76 256.2 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 KUM60146.1 - 0.0003 21.6 3.5 0.00073 20.3 1.5 2.6 1 1 1 2 2 2 1 AAA domain ArgK PF03308.11 KUM60146.1 - 0.00059 18.7 0.1 0.0013 17.5 0.0 1.5 2 0 0 2 2 2 1 ArgK protein AAA_10 PF12846.2 KUM60146.1 - 0.00099 18.6 0.1 0.021 14.2 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain CbiA PF01656.18 KUM60146.1 - 0.0028 17.0 0.0 0.0055 16.1 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.18 KUM60146.1 - 0.0051 16.7 0.0 0.015 15.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 KUM60146.1 - 0.0067 16.3 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KUM60146.1 - 0.11 11.6 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MipZ PF09140.6 KUM60146.1 - 0.11 11.5 0.0 0.41 9.6 0.0 1.9 2 1 0 2 2 2 0 ATPase MipZ AAA_29 PF13555.1 KUM60146.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 KUM60146.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 KUM60146.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain WD40 PF00400.27 KUM60147.1 - 8.5e-22 76.1 3.2 0.00018 21.2 0.2 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat SGL PF08450.7 KUM60147.1 - 0.11 11.8 0.0 0.33 10.3 0.0 1.8 1 1 1 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Citrate_synt PF00285.16 KUM60148.1 - 1.8e-18 66.4 0.0 5.5e-16 58.2 0.0 3.0 1 1 1 2 2 2 2 Citrate synthase CoA_binding PF02629.14 KUM60148.1 - 2.8e-18 66.2 0.0 1.1e-17 64.2 0.0 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 KUM60148.1 - 1.2e-14 54.1 0.1 2.2e-14 53.3 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KUM60148.1 - 2e-05 24.2 0.0 0.00042 19.9 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CEP1-DNA_bind PF09287.5 KUM60148.1 - 0.2 11.0 0.0 0.44 9.9 0.0 1.5 1 0 0 1 1 1 0 CEP-1, DNA binding RNase_P_Rpp14 PF01900.14 KUM60149.1 - 6.3e-36 122.5 0.0 9e-36 122.0 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family MBOAT_2 PF13813.1 KUM60150.1 - 2.1e-22 78.9 2.0 6.5e-22 77.3 1.4 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF4137 PF13593.1 KUM60150.1 - 0.011 14.9 1.5 0.021 13.9 0.0 2.0 2 0 0 2 2 2 0 SBF-like CPA transporter family (DUF4137) DUF3239 PF11580.3 KUM60150.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3239) ATP-grasp_2 PF08442.5 KUM60151.1 - 2e-08 33.8 0.0 3.1e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain SET PF00856.23 KUM60152.1 - 9.6e-05 22.7 0.1 0.0002 21.6 0.1 1.5 1 0 0 1 1 1 1 SET domain zf-RING_5 PF14634.1 KUM60153.1 - 3.4e-08 33.0 8.2 5.5e-08 32.4 5.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KUM60153.1 - 3e-05 23.7 4.6 5.5e-05 22.9 3.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KUM60153.1 - 0.00011 21.7 4.8 0.00024 20.6 3.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KUM60153.1 - 0.00019 21.3 4.8 0.00035 20.5 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KUM60153.1 - 0.00041 19.9 6.6 0.00069 19.2 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 KUM60153.1 - 0.0013 18.6 0.9 0.003 17.5 0.6 1.6 1 0 0 1 1 1 1 zinc-finger Allexi_40kDa PF05549.6 KUM60153.1 - 0.0017 17.7 2.4 0.0026 17.0 1.6 1.2 1 0 0 1 1 1 1 Allexivirus 40kDa protein DZR PF12773.2 KUM60153.1 - 0.0091 15.7 2.4 0.025 14.4 1.7 1.7 1 1 0 1 1 1 1 Double zinc ribbon zf-RING_6 PF14835.1 KUM60153.1 - 0.015 15.0 3.1 0.035 13.9 2.2 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KUM60153.1 - 0.041 13.7 3.3 0.091 12.6 2.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KUM60153.1 - 0.13 12.0 2.5 0.34 10.6 1.7 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Fib_alpha PF08702.5 KUM60153.1 - 0.17 11.9 9.0 0.28 11.2 6.3 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Spc24 PF08286.6 KUM60153.1 - 0.2 11.3 6.8 0.33 10.6 4.7 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Nup88 PF10168.4 KUM60153.1 - 0.22 9.3 5.5 0.28 8.9 3.8 1.1 1 0 0 1 1 1 0 Nuclear pore component IncA PF04156.9 KUM60153.1 - 0.27 10.8 4.4 0.39 10.2 3.1 1.2 1 0 0 1 1 1 0 IncA protein DUF3552 PF12072.3 KUM60153.1 - 0.38 9.9 6.2 0.56 9.3 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) zf-rbx1 PF12678.2 KUM60153.1 - 0.52 10.4 3.5 0.97 9.5 2.4 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger SbcD_C PF12320.3 KUM60153.1 - 0.67 10.0 3.0 1.1 9.3 0.9 2.0 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain OmpH PF03938.9 KUM60153.1 - 1.2 9.0 9.1 1.7 8.5 6.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Laminin_II PF06009.7 KUM60153.1 - 2.3 7.9 8.9 3.8 7.2 6.2 1.3 1 0 0 1 1 1 0 Laminin Domain II DUF342 PF03961.8 KUM60153.1 - 2.8 6.2 6.9 3.7 5.8 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Cpn10 PF00166.16 KUM60154.1 - 6.8e-27 93.2 0.0 7.7e-27 93.0 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit XAP5 PF04921.9 KUM60156.1 - 2e-80 269.8 0.9 3e-80 269.2 0.0 1.6 2 0 0 2 2 2 1 XAP5, circadian clock regulator Fip1 PF05182.8 KUM60157.1 - 2.2e-20 71.6 1.1 3.7e-20 70.9 0.8 1.4 1 0 0 1 1 1 1 Fip1 motif WD40 PF00400.27 KUM60158.1 - 2e-07 30.6 5.9 0.02 14.7 0.0 6.5 7 0 0 7 7 7 2 WD domain, G-beta repeat Lactonase PF10282.4 KUM60158.1 - 0.0081 15.2 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller HAD_2 PF13419.1 KUM60159.1 - 3e-11 43.8 0.0 5.3e-11 43.0 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KUM60159.1 - 5.1e-05 22.9 0.0 0.00042 19.9 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 KUM60159.1 - 0.00058 20.3 0.0 0.049 14.0 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIR_SIR PF01077.17 KUM60159.1 - 0.042 13.2 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain TauD PF02668.11 KUM60160.1 - 2.9e-45 154.9 0.2 3.7e-45 154.6 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Nucleoporin_FG PF13634.1 KUM60161.1 - 2.6e-09 37.3 95.2 1.5e+04 -5.3 66.0 2.8 1 1 0 1 1 1 0 Nucleoporin FG repeat region Baculo_PEP_C PF04513.7 KUM60161.1 - 0.0013 18.5 1.0 1.6 8.5 0.1 3.1 2 2 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 KUM60161.1 - 0.11 12.2 0.6 0.6 9.9 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 KUM60161.1 - 0.55 10.1 2.8 26 4.8 0.0 3.2 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) AMP-binding PF00501.23 KUM60162.1 - 2.4e-76 256.8 0.0 3.1e-76 256.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KUM60162.1 - 1.2e-14 54.9 0.5 6.2e-14 52.6 0.1 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain NDUF_B12 PF08122.7 KUM60163.1 - 2.6e-20 71.8 1.5 4.1e-20 71.2 1.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family WD40 PF00400.27 KUM60164.1 - 5.2e-30 102.2 3.6 0.00016 21.4 0.0 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KUM60164.1 - 0.011 15.2 0.0 1.9 8.0 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Cu_amine_oxid PF01179.15 KUM60165.1 - 6.6e-169 561.9 0.0 8.1e-169 561.7 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KUM60165.1 - 5.4e-23 80.9 1.1 2.4e-21 75.6 0.0 2.5 1 1 1 2 2 2 2 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KUM60165.1 - 3.2e-15 55.9 0.0 5.7e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain CAF1 PF04857.15 KUM60166.1 - 4e-64 216.4 0.0 6.2e-64 215.8 0.0 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease adh_short_C2 PF13561.1 KUM60167.1 - 1e-22 81.0 0.0 3.4e-22 79.3 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KUM60167.1 - 8.8e-18 64.7 0.3 1.6e-17 63.9 0.2 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM60167.1 - 1e-05 25.2 0.2 1.9e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF4056 PF13265.1 KUM60167.1 - 0.051 12.5 0.0 0.081 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4056) Polysacc_synt_2 PF02719.10 KUM60167.1 - 0.11 11.4 0.1 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein BBIP10 PF14777.1 KUM60167.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Cilia BBSome complex subunit 10 CNH PF00780.17 KUM60168.1 - 2.7e-69 233.6 0.0 4.9e-69 232.8 0.0 1.4 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 KUM60168.1 - 3.6e-33 114.9 0.8 3.6e-33 114.9 0.6 1.7 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.1 KUM60168.1 - 2.4e-13 50.2 0.0 7.5e-13 48.5 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PAP2_C PF14360.1 KUM60169.1 - 0.027 14.7 0.0 4.9 7.5 0.0 2.2 2 0 0 2 2 2 0 PAP2 superfamily C-terminal RabGAP-TBC PF00566.13 KUM60171.1 - 4.2e-46 157.1 0.0 7.3e-46 156.3 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 KUM60171.1 - 0.0073 16.1 0.2 0.035 13.9 0.1 2.2 1 0 0 1 1 1 1 EF-hand domain GRAM PF02893.15 KUM60171.1 - 0.013 15.0 0.0 0.031 13.8 0.0 1.7 1 1 0 1 1 1 0 GRAM domain Fungal_trans PF04082.13 KUM60173.1 - 7.2e-10 38.1 1.7 9e-10 37.8 0.5 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM60173.1 - 5.9e-06 26.0 13.9 5.9e-06 26.0 9.7 2.4 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2OG-FeII_Oxy_2 PF13532.1 KUM60174.1 - 6.6e-30 104.3 0.0 1.1e-29 103.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SHOCT PF09851.4 KUM60174.1 - 0.00036 19.8 1.6 0.0008 18.7 1.1 1.6 1 0 0 1 1 1 1 Short C-terminal domain Fungal_trans PF04082.13 KUM60175.1 - 1.9e-16 59.7 0.6 1.9e-16 59.7 0.4 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain ImpA-rel_N PF06812.7 KUM60175.1 - 0.013 15.2 2.2 1.8 8.4 0.0 2.8 3 0 0 3 3 3 0 ImpA-related N-terminal DUF1772 PF08592.6 KUM60176.1 - 0.00019 21.1 0.9 0.021 14.5 0.3 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1772) TraX PF05857.6 KUM60176.1 - 0.082 12.5 0.4 0.16 11.6 0.2 1.5 1 1 0 1 1 1 0 TraX protein Vir_act_alpha_C PF10400.4 KUM60176.1 - 0.1 12.9 0.2 0.24 11.7 0.2 1.6 1 0 0 1 1 1 0 Virulence activator alpha C-term MRAP PF15183.1 KUM60177.1 - 0.092 12.3 0.2 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family IncA PF04156.9 KUM60177.1 - 0.71 9.4 15.9 1.6 8.2 8.8 2.3 1 1 1 2 2 2 0 IncA protein Velvet PF11754.3 KUM60178.1 - 2.8e-63 213.2 0.0 3.8e-63 212.7 0.0 1.2 1 0 0 1 1 1 1 Velvet factor Atrophin-1 PF03154.10 KUM60178.1 - 0.00011 20.5 2.2 0.00011 20.5 1.5 2.0 2 0 0 2 2 2 1 Atrophin-1 family DUF1777 PF08648.7 KUM60178.1 - 0.51 10.0 19.4 1 9.0 13.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Peptidase_M48 PF01435.13 KUM60180.1 - 5.7e-35 120.9 0.1 7.6e-35 120.5 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M48 Cpn60_TCP1 PF00118.19 KUM60181.1 - 9.6e-135 449.9 2.1 1.1e-134 449.7 1.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_L12 PF00542.14 KUM60182.1 - 2.2e-18 65.9 3.7 2.4e-17 62.6 1.7 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain TPR_6 PF13174.1 KUM60183.1 - 0.41 11.1 7.8 1.1 9.8 0.0 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 KUM60183.1 - 0.65 10.7 3.9 2.6 8.8 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KUM60183.1 - 1.3 9.4 4.5 4.1 7.8 0.1 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat E1_dh PF00676.15 KUM60185.1 - 2.7e-114 380.9 0.5 3.2e-114 380.7 0.3 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KUM60185.1 - 0.00081 18.3 0.0 0.0014 17.6 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Glyco_hydro_14 PF01373.12 KUM60186.1 - 0.079 11.6 0.0 0.097 11.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 14 PH_10 PF15411.1 KUM60187.1 - 2.3e-23 82.5 0.0 4e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 KUM60187.1 - 1.5e-12 47.5 0.0 8.1e-12 45.0 0.0 2.3 2 1 0 2 2 2 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 KUM60187.1 - 2.6e-08 33.5 8.8 5.1e-08 32.6 6.1 1.5 1 0 0 1 1 1 1 Ring finger domain VWA PF00092.23 KUM60187.1 - 1.2e-07 31.6 0.0 2.7e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_5 PF14634.1 KUM60187.1 - 0.0059 16.3 7.1 0.01 15.5 4.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KUM60187.1 - 0.0072 16.4 3.3 0.015 15.3 2.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KUM60187.1 - 0.06 13.3 7.1 0.11 12.5 4.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KUM60187.1 - 0.15 11.7 7.1 0.28 10.8 4.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 KUM60187.1 - 7.2 6.7 7.2 14 5.7 5.0 1.5 1 0 0 1 1 1 0 RING-like domain DUF77 PF01910.12 KUM60189.1 - 6.5e-31 105.8 0.2 7.5e-31 105.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 Ins_P5_2-kin PF06090.7 KUM60190.1 - 3.2e-73 246.4 0.0 3.7e-73 246.2 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase S4 PF01479.20 KUM60191.1 - 6.1e-16 57.5 0.9 1.2e-15 56.6 0.0 2.0 2 0 0 2 2 2 1 S4 domain S4_2 PF13275.1 KUM60191.1 - 0.081 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 S4 domain PI-PLC-X PF00388.14 KUM60192.1 - 0.017 14.4 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain DUF3368 PF11848.3 KUM60193.1 - 0.073 12.6 0.3 0.26 10.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) NAD_binding_10 PF13460.1 KUM60194.1 - 1.5e-11 44.6 0.0 3.7e-10 40.0 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KUM60194.1 - 1.4e-06 27.9 0.0 2.8e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KUM60194.1 - 5.2e-05 22.0 0.0 0.00065 18.4 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KUM60194.1 - 0.0022 17.9 0.0 0.0058 16.5 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KUM60194.1 - 0.023 13.6 0.0 1 8.2 0.0 2.4 2 0 0 2 2 2 0 Male sterility protein RmlD_sub_bind PF04321.12 KUM60194.1 - 0.043 12.7 0.0 0.23 10.3 0.0 2.1 2 1 0 2 2 2 0 RmlD substrate binding domain SYF2 PF08231.7 KUM60195.1 - 2.7e-54 183.4 13.1 2.7e-54 183.4 9.1 2.1 2 0 0 2 2 2 1 SYF2 splicing factor IDO PF01231.13 KUM60196.1 - 1.3e-143 478.4 0.0 1.6e-143 478.1 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase YEATS PF03366.11 KUM60197.1 - 5.9e-35 118.8 1.2 8.8e-35 118.2 0.8 1.3 1 0 0 1 1 1 1 YEATS family Aminotran_5 PF00266.14 KUM60198.1 - 9.5e-10 37.7 0.0 9.2e-09 34.5 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V COX7a PF02238.10 KUM60200.1 - 0.43 10.3 1.7 0.46 10.2 0.0 1.9 2 1 0 2 2 2 0 Cytochrome c oxidase subunit VIIa Fungal_trans PF04082.13 KUM60201.1 - 3.5e-14 52.3 0.3 8.2e-13 47.8 0.3 2.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM60201.1 - 4.6e-08 32.8 10.9 8.6e-08 31.9 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_RNApol_7kD PF03604.8 KUM60202.1 - 8.6e-17 60.3 5.2 1.1e-16 59.9 3.6 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DUF2197 PF09963.4 KUM60202.1 - 0.0005 19.9 0.9 0.08 12.9 0.0 2.2 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2197) HypA PF01155.14 KUM60202.1 - 0.0013 18.4 0.1 0.0015 18.2 0.0 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family DZR PF12773.2 KUM60202.1 - 0.0026 17.5 0.2 0.0037 17.0 0.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon A2L_zn_ribbon PF08792.5 KUM60202.1 - 0.0057 16.0 1.5 0.072 12.5 0.1 2.1 2 0 0 2 2 2 1 A2L zinc ribbon domain GFA PF04828.9 KUM60202.1 - 0.026 14.4 0.2 0.055 13.4 0.2 1.6 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF2082 PF09855.4 KUM60202.1 - 0.03 14.1 0.1 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Zn-ribbon_8 PF09723.5 KUM60202.1 - 0.08 12.9 0.9 0.13 12.2 0.6 1.4 1 0 0 1 1 1 0 Zinc ribbon domain DUF2318 PF10080.4 KUM60202.1 - 0.081 12.6 0.2 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) TFIIS_C PF01096.13 KUM60202.1 - 0.11 12.1 0.7 4.4 7.0 0.1 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Ribosomal_L40e PF01020.12 KUM60202.1 - 0.13 11.8 2.9 0.19 11.3 2.0 1.2 1 0 0 1 1 1 0 Ribosomal L40e family UPF0547 PF10571.4 KUM60202.1 - 0.14 11.8 1.6 0.42 10.3 1.1 1.7 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 RRN7 PF11781.3 KUM60202.1 - 0.28 10.7 3.3 3.1 7.3 0.1 2.2 1 1 1 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zinc_ribbon_4 PF13717.1 KUM60202.1 - 1.2 8.8 3.8 5.3 6.8 2.7 1.9 1 1 1 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KUM60202.1 - 1.5 8.4 3.9 5.6 6.6 2.7 1.9 1 1 0 1 1 1 0 zinc-ribbon domain Glycos_transf_3 PF00591.16 KUM60203.1 - 2.1e-58 197.6 0.0 2.7e-56 190.8 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 KUM60203.1 - 8.2e-08 31.7 0.2 2.1e-07 30.4 0.2 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain DUF2263 PF10021.4 KUM60204.1 - 6.3e-27 94.3 1.0 8.6e-27 93.9 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2263) DUF2219 PF09982.4 KUM60204.1 - 0.015 14.1 0.0 0.026 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2219) Macro PF01661.16 KUM60204.1 - 0.09 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Macro domain Fe_hyd_lg_C PF02906.9 KUM60205.1 - 7.8e-59 199.2 0.0 1.3e-58 198.5 0.0 1.4 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fapy_DNA_glyco PF01149.19 KUM60206.1 - 2.7e-26 92.2 0.0 5.2e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 KUM60206.1 - 1.1e-21 76.3 0.0 1.9e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 KUM60206.1 - 0.0013 17.3 0.0 0.0087 14.6 0.0 2.1 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) Abhydrolase_2 PF02230.11 KUM60207.1 - 1.1e-27 96.8 0.0 1.4e-17 63.8 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KUM60207.1 - 6.9e-06 26.1 0.0 9.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM60207.1 - 3.3e-05 23.6 0.0 0.00014 21.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KUM60207.1 - 0.0026 16.9 0.2 0.0052 16.0 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family LIP PF03583.9 KUM60207.1 - 0.011 14.8 0.1 2.3 7.3 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase RPA_interact_M PF14767.1 KUM60207.1 - 1 10.1 5.8 4.2 8.1 0.0 3.2 3 1 1 4 4 4 0 Replication protein A interacting middle Sorting_nexin PF03700.8 KUM60207.1 - 1.7 8.7 10.8 4.5 7.3 4.5 2.2 1 1 1 2 2 2 0 Sorting nexin, N-terminal domain NARP1 PF12569.3 KUM60208.1 - 9.2e-213 707.6 20.9 1.1e-210 700.7 10.2 2.2 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_16 PF13432.1 KUM60208.1 - 2.1e-19 69.6 19.0 0.00068 20.2 0.6 9.0 7 1 1 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 KUM60208.1 - 3e-19 67.7 21.6 0.013 16.1 0.1 12.1 8 3 4 12 12 12 5 Tetratricopeptide repeat TPR_19 PF14559.1 KUM60208.1 - 2.6e-18 66.1 29.0 0.0028 17.9 0.6 7.9 6 2 1 7 7 6 5 Tetratricopeptide repeat TPR_11 PF13414.1 KUM60208.1 - 4.1e-18 64.7 27.8 1.1e-06 28.2 0.1 7.8 7 2 1 8 8 8 5 TPR repeat TPR_2 PF07719.12 KUM60208.1 - 5.6e-16 57.0 29.2 0.00035 20.2 0.1 10.6 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_17 PF13431.1 KUM60208.1 - 2.8e-08 33.3 12.7 0.86 9.9 0.1 7.8 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 KUM60208.1 - 1.4e-07 30.7 29.1 9.3e-05 21.8 0.1 9.4 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_12 PF13424.1 KUM60208.1 - 4.3e-07 29.7 17.3 0.02 14.8 0.2 7.0 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 KUM60208.1 - 2.9e-05 23.8 13.1 0.0015 18.3 1.3 5.7 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 KUM60208.1 - 0.00014 21.3 12.9 0.011 15.4 0.0 6.7 7 0 0 7 7 6 1 Tetratricopeptide repeat Apc3 PF12895.2 KUM60208.1 - 0.00077 19.5 21.2 0.015 15.4 0.4 6.8 3 2 4 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 KUM60208.1 - 0.0032 17.3 3.7 13 5.7 0.0 5.2 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat DUF3087 PF11286.3 KUM60208.1 - 0.014 14.5 3.2 0.13 11.4 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) MIT PF04212.13 KUM60208.1 - 0.026 14.3 0.1 0.026 14.3 0.1 4.8 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 KUM60208.1 - 0.04 13.7 2.6 0.16 11.8 0.0 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KUM60208.1 - 0.13 12.7 20.2 5.9 7.5 0.1 7.5 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_7 PF13176.1 KUM60208.1 - 0.45 10.4 11.0 4.9 7.1 0.0 6.4 6 1 1 7 7 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 KUM60208.1 - 3.3 8.4 15.2 0.17 12.4 0.5 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat BTAD PF03704.12 KUM60208.1 - 4.4 7.5 11.9 0.14 12.5 0.3 3.3 3 1 0 3 3 3 0 Bacterial transcriptional activator domain Cid2 PF09774.4 KUM60209.1 - 2.5e-52 176.9 0.2 2.9e-52 176.7 0.2 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Ribosomal_L10 PF00466.15 KUM60210.1 - 0.044 13.7 0.0 0.26 11.2 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L10 PI-PLC-X PF00388.14 KUM60211.1 - 6.5e-10 38.5 0.0 1.8e-09 37.1 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain TRI5 PF06330.6 KUM60213.1 - 6.8e-36 123.6 0.0 8.9e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) p450 PF00067.17 KUM60214.1 - 1.3e-55 188.8 0.0 1.5e-55 188.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tim54 PF11711.3 KUM60215.1 - 5.5e-146 486.0 0.5 6.5e-146 485.8 0.4 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 2-oxoacid_dh PF00198.18 KUM60216.1 - 1.5e-77 260.0 0.1 2.1e-77 259.5 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KUM60216.1 - 1.6e-13 50.0 0.0 3.2e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KUM60216.1 - 5.3e-12 45.1 1.2 8e-12 44.5 0.1 1.9 2 0 0 2 2 2 1 e3 binding domain COesterase PF00135.23 KUM60217.1 - 5.3e-79 266.3 4.2 1e-78 265.4 2.9 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 KUM60217.1 - 3.1e-05 23.3 0.1 6.3e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 KUM60217.1 - 0.0012 18.4 0.0 0.0026 17.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Phytase PF02333.10 KUM60218.1 - 9.4e-65 218.7 3.1 1.7e-61 208.0 0.2 2.2 2 0 0 2 2 2 2 Phytase EGF_2 PF07974.8 KUM60218.1 - 0.0056 16.8 11.3 0.0056 16.8 7.8 2.0 2 0 0 2 2 2 1 EGF-like domain Lactonase PF10282.4 KUM60218.1 - 0.021 13.9 0.1 6.9 5.6 0.0 3.1 3 1 0 3 3 3 0 Lactonase, 7-bladed beta-propeller UQ_con PF00179.21 KUM60220.1 - 5.4e-17 61.5 0.0 6.3e-17 61.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KUM60220.1 - 0.014 15.2 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 0 RWD domain Sec7_N PF12783.2 KUM60221.1 - 5.2e-41 139.8 2.9 1.5e-40 138.3 0.0 3.1 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KUM60221.1 - 0.017 14.6 0.6 0.33 10.4 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF1981) DUF2763 PF10961.3 KUM60221.1 - 1.6 9.1 2.2 2.5 8.5 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2763) Ipi1_N PF12333.3 KUM60221.1 - 3.7 7.5 8.8 1 9.3 0.0 4.4 5 0 0 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation Vps26 PF03643.10 KUM60222.1 - 6.6e-129 428.5 0.2 8.2e-129 428.2 0.2 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 KUM60222.1 - 0.00091 19.0 0.7 1.2 8.9 0.0 3.2 4 0 0 4 4 4 2 Arrestin (or S-antigen), N-terminal domain DUF432 PF04254.8 KUM60222.1 - 0.06 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF432) SKI PF01202.17 KUM60223.1 - 5.6e-12 45.8 0.0 8.2e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.1 KUM60223.1 - 2.7e-09 37.0 0.0 3.9e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KUM60223.1 - 4e-08 34.1 0.0 5.2e-08 33.7 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KUM60223.1 - 4.5e-07 30.2 0.0 1e-06 29.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KUM60223.1 - 0.0057 15.8 0.0 0.0073 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KUM60223.1 - 0.0072 16.3 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.10 KUM60223.1 - 0.0074 15.0 0.0 0.011 14.4 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein NTPase_1 PF03266.10 KUM60223.1 - 0.0094 15.6 0.5 3.5 7.3 0.0 2.2 2 0 0 2 2 2 2 NTPase RNA_helicase PF00910.17 KUM60223.1 - 0.013 15.6 0.0 0.031 14.4 0.0 1.7 2 0 0 2 2 1 0 RNA helicase AAA_22 PF13401.1 KUM60223.1 - 0.015 15.4 0.0 0.041 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KUM60223.1 - 0.021 14.3 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 KUM60223.1 - 0.023 14.9 0.0 0.049 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 KUM60223.1 - 0.023 14.9 0.0 0.053 13.8 0.0 1.6 2 0 0 2 2 1 0 ABC transporter AAA_28 PF13521.1 KUM60223.1 - 0.027 14.4 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KUM60223.1 - 0.05 13.1 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 KUM60223.1 - 0.068 12.0 0.3 0.12 11.2 0.2 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein CoaE PF01121.15 KUM60223.1 - 0.075 12.4 0.0 0.2 11.0 0.0 1.7 1 0 0 1 1 1 0 Dephospho-CoA kinase Thymidylate_kin PF02223.12 KUM60223.1 - 0.083 12.2 0.0 1 8.7 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase DUF2075 PF09848.4 KUM60223.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 KUM60223.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 KUM60223.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Methyltransf_25 PF13649.1 KUM60223.1 - 0.14 12.5 0.0 0.53 10.6 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain p450 PF00067.17 KUM60225.1 - 6.7e-51 173.2 0.0 8.1e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Lipase_3 PF01764.20 KUM60229.1 - 4e-07 29.7 0.0 1.5e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) Peptidase_M61 PF05299.7 KUM60229.1 - 0.33 10.9 1.9 13 5.7 0.0 2.9 3 1 1 4 4 4 0 M61 glycyl aminopeptidase Catalase PF00199.14 KUM60230.1 - 9.5e-185 613.7 1.2 1.1e-184 613.5 0.9 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KUM60230.1 - 3.8e-12 45.8 0.1 1.2e-11 44.3 0.0 1.9 2 0 0 2 2 2 1 Catalase-related immune-responsive DUF3419 PF11899.3 KUM60231.1 - 7.1e-155 515.4 0.0 1e-154 514.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_31 PF13847.1 KUM60231.1 - 8.8e-08 31.8 0.0 1.1e-06 28.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KUM60231.1 - 1.1e-06 27.9 0.0 2.3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 KUM60231.1 - 1.4e-06 28.0 0.0 0.00015 21.5 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM60231.1 - 3.2e-06 27.5 0.0 1.3e-05 25.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM60231.1 - 8.6e-06 26.3 0.0 0.0001 22.8 0.0 2.7 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM60231.1 - 5.3e-05 23.6 0.0 0.0019 18.6 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 KUM60231.1 - 9.1e-05 22.4 0.0 0.00097 19.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM60231.1 - 0.002 18.4 0.0 0.018 15.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain DmpG_comm PF07836.6 KUM60232.1 - 0.073 12.4 0.2 0.18 11.2 0.1 1.7 1 1 1 2 2 2 0 DmpG-like communication domain PepSY_TM PF03929.11 KUM60232.1 - 5 7.7 7.9 4.6 7.8 4.0 2.1 2 1 0 2 2 2 0 PepSY-associated TM helix Ank_2 PF12796.2 KUM60233.1 - 4.3e-18 65.4 0.0 2.3e-13 50.2 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KUM60233.1 - 2.2e-11 42.8 0.5 0.36 11.2 0.0 6.0 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 KUM60233.1 - 3.5e-10 40.1 0.5 3.1e-05 24.3 0.0 4.4 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KUM60233.1 - 1.2e-09 37.5 4.3 0.02 14.6 0.0 5.7 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.1 KUM60233.1 - 4.1e-09 36.3 0.1 0.031 14.5 0.0 4.4 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Glyco_hydro_28 PF00295.12 KUM60234.1 - 2.9e-99 332.1 20.5 3.2e-99 331.9 14.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Allene_ox_cyc PF06351.6 KUM60234.1 - 0.0087 15.5 1.8 0.04 13.3 0.4 2.3 1 1 1 2 2 2 1 Allene oxide cyclase Sugar_tr PF00083.19 KUM60235.1 - 4.1e-83 279.4 21.8 4.8e-83 279.2 15.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM60235.1 - 2.6e-16 59.3 27.2 5.5e-14 51.6 13.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_80 PF13647.1 KUM60235.1 - 0.052 12.8 0.0 5.4 6.1 0.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase family 80 of chitosanase A ECH PF00378.15 KUM60236.1 - 5e-73 245.2 0.0 6.6e-73 244.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 KUM60236.1 - 0.02 15.0 0.1 0.064 13.4 0.0 1.8 2 0 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region Rer1 PF03248.8 KUM60237.1 - 3.8e-82 274.1 2.2 4.2e-82 273.9 1.5 1.0 1 0 0 1 1 1 1 Rer1 family DUF962 PF06127.6 KUM60237.1 - 0.21 11.5 3.9 2.1 8.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF962) Ctr PF04145.10 KUM60238.1 - 1.5e-17 63.9 0.0 2.8e-17 63.0 0.0 1.4 1 1 0 1 1 1 1 Ctr copper transporter family Formyl_trans_N PF00551.14 KUM60239.1 - 2.8e-38 131.2 0.1 3.3e-38 131.0 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase ECM11 PF15463.1 KUM60240.1 - 6.6e-44 149.5 0.0 6.6e-44 149.5 0.0 2.5 3 1 0 3 3 3 1 Extracellular mutant protein 11 VPS9 PF02204.13 KUM60241.1 - 1.5e-25 89.1 0.1 3e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain zf-RING_2 PF13639.1 KUM60242.1 - 1.4e-15 56.8 4.6 2.2e-15 56.1 3.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KUM60242.1 - 7.7e-11 41.9 0.8 1.4e-10 41.1 0.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KUM60242.1 - 6.3e-08 32.1 3.5 9.8e-08 31.5 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KUM60242.1 - 1.7e-07 31.1 4.1 3e-07 30.3 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KUM60242.1 - 3.2e-06 26.9 0.4 6.1e-06 25.9 0.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 KUM60242.1 - 8.4e-06 25.4 2.8 1.3e-05 24.8 1.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KUM60242.1 - 4.4e-05 23.0 1.4 7.5e-05 22.3 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 KUM60242.1 - 0.00077 19.4 5.2 0.0012 18.8 3.6 1.3 1 0 0 1 1 1 1 RING-variant domain zf-Nse PF11789.3 KUM60242.1 - 0.0058 16.1 1.0 0.013 14.9 0.7 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 KUM60242.1 - 0.029 14.3 2.5 0.052 13.5 1.7 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 KUM60242.1 - 0.035 13.8 1.2 0.085 12.5 0.8 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING-like PF08746.6 KUM60242.1 - 0.038 13.9 1.7 0.069 13.1 1.2 1.3 1 0 0 1 1 1 0 RING-like domain zf-RING_6 PF14835.1 KUM60242.1 - 0.057 13.2 1.5 0.11 12.2 1.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 KUM60242.1 - 0.15 11.6 3.3 0.24 11.0 2.3 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RNA_pol_I_TF PF04090.7 KUM60243.1 - 1.1e-10 41.1 0.0 1.2e-09 37.7 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor SNF2_N PF00176.18 KUM60244.1 - 4.6e-64 216.0 0.0 6.2e-64 215.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 KUM60244.1 - 2.3e-57 193.9 2.1 1.3e-56 191.5 1.9 1.9 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 KUM60244.1 - 1.1e-12 47.6 0.0 2.7e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KUM60244.1 - 5.5e-06 25.4 0.0 1.8e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KUM60244.1 - 0.00059 19.7 0.0 0.0021 17.9 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit adh_short PF00106.20 KUM60245.1 - 8.2e-18 64.8 0.0 1.3e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM60245.1 - 2.4e-09 37.1 0.0 3.1e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KUM60245.1 - 6.7e-07 29.3 0.0 9.5e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KUM60245.1 - 0.0037 16.7 0.0 0.012 15.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family FMO-like PF00743.14 KUM60245.1 - 0.11 10.6 0.0 0.15 10.2 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Vac14_Fig4_bd PF11916.3 KUM60247.1 - 1.2e-82 275.4 7.0 1.2e-82 275.4 4.8 2.1 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 KUM60247.1 - 3.9e-44 148.9 0.0 8.5e-42 141.4 0.0 3.8 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 KUM60247.1 - 9.2e-10 38.6 0.2 0.007 16.6 0.0 5.3 5 2 0 6 6 6 3 HEAT repeats HEAT PF02985.17 KUM60247.1 - 3.5e-09 35.9 0.8 0.00021 21.0 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 KUM60247.1 - 5.7e-09 36.2 1.9 0.003 17.9 0.0 5.4 6 0 0 6 6 6 2 HEAT-like repeat Cnd1 PF12717.2 KUM60247.1 - 0.00018 21.4 0.9 0.29 10.9 0.0 3.2 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 KUM60247.1 - 0.008 15.9 0.0 14 5.6 0.0 4.7 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Ipi1_N PF12333.3 KUM60247.1 - 0.052 13.5 0.0 3.1 7.8 0.0 3.4 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation DUF3385 PF11865.3 KUM60247.1 - 0.13 12.1 1.9 7.1 6.5 0.0 3.9 4 1 1 5 5 5 0 Domain of unknown function (DUF3385) WD40 PF00400.27 KUM60249.1 - 2.1e-55 182.7 17.1 2.7e-09 36.5 0.2 8.5 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 KUM60249.1 - 3.5e-09 36.2 0.2 6.9e-09 35.3 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KUM60249.1 - 5.2e-08 32.3 0.2 2.1e-07 30.4 0.2 2.1 1 1 1 2 2 2 1 F-box domain Nup160 PF11715.3 KUM60249.1 - 1.6 6.7 17.4 0.63 8.1 0.2 5.1 3 2 2 5 5 5 0 Nucleoporin Nup120/160 HORMA PF02301.13 KUM60250.1 - 3.9e-28 98.3 0.0 6.6e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 HORMA domain PHD PF00628.24 KUM60250.1 - 5e-05 22.8 8.2 9.6e-05 22.0 5.7 1.5 1 0 0 1 1 1 1 PHD-finger DUF3759 PF12585.3 KUM60252.1 - 3.5e-36 122.9 5.8 4.4e-36 122.6 4.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Ribosomal_L7Ae PF01248.21 KUM60253.1 - 3.9e-23 80.7 0.6 6.1e-23 80.1 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KUM60253.1 - 0.00034 20.4 0.0 0.00052 19.8 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 Clat_adaptor_s PF01217.15 KUM60254.1 - 2.6e-42 143.9 0.0 5.3e-42 142.9 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain CHASE4 PF05228.8 KUM60254.1 - 0.072 12.6 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 CHASE4 domain MMR_HSR1 PF01926.18 KUM60255.1 - 2.5e-20 72.5 0.0 3.8e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KUM60255.1 - 3e-06 27.1 0.0 0.00023 20.9 0.0 2.2 2 0 0 2 2 2 1 Dynamin family AIG1 PF04548.11 KUM60255.1 - 0.00033 19.8 0.0 0.00047 19.3 0.0 1.1 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 KUM60255.1 - 0.00045 19.6 0.0 0.0057 16.1 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KUM60255.1 - 0.00047 19.4 0.0 0.00062 19.0 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 KUM60255.1 - 0.002 17.4 0.0 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 KUM60255.1 - 0.0026 16.9 0.0 0.0043 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KUM60255.1 - 0.0075 15.7 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KUM60255.1 - 0.024 14.9 0.1 0.051 13.8 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 KUM60255.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KUM60255.1 - 0.1 13.1 0.0 0.16 12.4 0.0 1.5 1 1 0 1 1 1 0 Miro-like protein HEAT_2 PF13646.1 KUM60256.1 - 2.3e-08 34.1 1.0 0.26 11.5 0.0 5.0 3 1 2 5 5 5 3 HEAT repeats CLASP_N PF12348.3 KUM60256.1 - 7.7e-07 28.6 0.0 2.9e-05 23.5 0.0 2.7 3 0 0 3 3 3 1 CLASP N terminal HEAT PF02985.17 KUM60256.1 - 2.5e-05 23.9 0.7 6.8 7.0 0.0 6.0 6 0 0 6 6 6 1 HEAT repeat IncA PF04156.9 KUM60256.1 - 0.0037 16.8 3.0 0.011 15.3 2.1 1.8 1 0 0 1 1 1 1 IncA protein V_ATPase_I PF01496.14 KUM60256.1 - 0.0071 14.2 0.5 0.011 13.6 0.3 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family COG5 PF10392.4 KUM60256.1 - 0.022 14.7 6.2 0.034 14.1 3.1 2.2 3 0 0 3 3 3 0 Golgi transport complex subunit 5 TAN PF11640.3 KUM60256.1 - 0.039 13.6 0.0 0.21 11.2 0.0 2.2 1 1 0 1 1 1 0 Telomere-length maintenance and DNA damage repair CAS_CSE1 PF03378.10 KUM60256.1 - 0.056 11.7 0.0 0.12 10.6 0.0 1.4 2 0 0 2 2 2 0 CAS/CSE protein, C-terminus ADIP PF11559.3 KUM60256.1 - 0.066 13.1 13.0 0.19 11.5 9.0 1.8 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding CENP-Q PF13094.1 KUM60256.1 - 0.081 12.9 11.2 0.24 11.4 7.8 1.7 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit APG6 PF04111.7 KUM60256.1 - 0.16 10.9 13.3 0.046 12.7 6.9 1.7 2 0 0 2 2 2 0 Autophagy protein Apg6 Myosin_tail_1 PF01576.14 KUM60256.1 - 0.32 8.6 16.0 0.5 8.0 11.1 1.2 1 0 0 1 1 1 0 Myosin tail Spc7 PF08317.6 KUM60256.1 - 1.3 7.6 8.8 2.6 6.6 6.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_13 PF13166.1 KUM60256.1 - 2.3 6.5 6.6 5.6 5.2 4.6 1.6 1 0 0 1 1 1 0 AAA domain CENP-F_leu_zip PF10473.4 KUM60256.1 - 4.1 7.2 15.1 19 5.0 8.5 3.1 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 KUM60256.1 - 6.1 6.5 18.3 29 4.4 0.1 3.2 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Mito_carr PF00153.22 KUM60258.1 - 2.7e-48 161.6 1.3 4.7e-21 74.2 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein O-antigen_lig PF13425.1 KUM60258.1 - 0.09 12.7 3.3 0.36 10.7 1.5 2.1 1 1 1 2 2 2 0 O-antigen ligase like membrane protein Aconitase PF00330.15 KUM60259.1 - 9.1e-175 581.6 0.0 1.9e-174 580.5 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KUM60259.1 - 1.7e-45 154.3 0.0 3.2e-45 153.4 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.3 KUM60260.1 - 9.4e-09 35.1 3.6 1.5e-08 34.5 2.5 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.7 KUM60260.1 - 0.00065 19.2 0.7 0.0011 18.4 0.5 1.4 1 0 0 1 1 1 1 U1 zinc finger zf-met PF12874.2 KUM60260.1 - 0.0013 18.8 1.9 0.0021 18.1 1.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KUM60260.1 - 0.021 14.9 0.5 0.038 14.1 0.3 1.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 KUM60260.1 - 0.027 14.7 0.7 0.054 13.8 0.5 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KUM60260.1 - 0.075 13.4 0.6 0.16 12.3 0.4 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KUM60260.1 - 0.28 11.1 1.8 0.29 11.1 0.2 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger Glyco_transf_20 PF00982.16 KUM60261.1 - 2.3e-200 666.0 0.0 2.7e-200 665.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 KUM60261.1 - 0.037 13.5 0.4 0.095 12.1 0.1 1.8 2 0 0 2 2 2 0 Starch synthase catalytic domain WD40 PF00400.27 KUM60263.1 - 1.9e-77 252.6 20.7 1.5e-12 46.8 0.5 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KUM60263.1 - 3.8e-10 38.5 2.8 0.0082 14.3 0.1 3.9 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KUM60263.1 - 0.0034 16.1 0.2 9.9 4.7 0.0 3.8 1 1 2 4 4 4 2 Nup133 N terminal like Ribosomal_S17 PF00366.15 KUM60264.1 - 0.02 14.9 0.5 0.041 13.9 0.3 1.5 1 0 0 1 1 1 0 Ribosomal protein S17 LSM PF01423.17 KUM60265.1 - 2.1e-17 62.4 0.0 3.8e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KUM60265.1 - 0.0078 16.1 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain P63C PF10546.4 KUM60265.1 - 0.034 14.0 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 P63C domain RAM PF15320.1 KUM60265.1 - 1 9.6 6.5 1.4 9.1 4.5 1.2 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein Hat1_N PF10394.4 KUM60266.1 - 1.7e-44 151.7 0.0 3.3e-44 150.8 0.0 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus PPR_3 PF13812.1 KUM60268.1 - 9.3e-19 66.0 7.7 0.00065 19.7 0.0 8.5 8 1 1 9 9 9 4 Pentatricopeptide repeat domain PPR_2 PF13041.1 KUM60268.1 - 5.8e-12 45.3 0.1 0.0027 17.6 0.0 7.5 5 3 4 9 9 9 3 PPR repeat family PPR PF01535.15 KUM60268.1 - 7.7e-06 25.5 7.9 3.9 7.6 0.1 7.2 8 0 0 8 8 8 2 PPR repeat PPR_1 PF12854.2 KUM60268.1 - 0.017 14.5 0.0 28 4.3 0.0 4.7 6 0 0 6 6 6 0 PPR repeat DUF1764 PF08576.5 KUM60268.1 - 0.57 10.9 3.0 1.6 9.5 2.1 1.7 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) p450 PF00067.17 KUM60273.1 - 1.7e-67 227.9 0.0 2e-67 227.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RNase_T PF00929.19 KUM60275.1 - 2.9e-14 53.6 0.0 5.7e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 KUM60275.1 - 0.013 14.9 0.0 0.027 13.9 0.0 1.6 1 0 0 1 1 1 0 3'-5' exonuclease zf-C2H2_6 PF13912.1 KUM60275.1 - 0.023 14.6 0.1 0.062 13.2 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KUM60275.1 - 0.029 14.5 1.3 8.2 6.7 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KUM60275.1 - 0.033 14.2 0.1 0.43 10.7 0.0 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KUM60275.1 - 0.15 12.3 1.7 2.1 8.6 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type TPR_1 PF00515.23 KUM60278.1 - 8.6e-49 161.2 26.8 3.7e-08 32.6 0.0 10.8 11 1 0 11 11 11 8 Tetratricopeptide repeat TPR_11 PF13414.1 KUM60278.1 - 5.7e-44 147.6 16.0 1.6e-10 40.4 0.3 5.8 3 2 1 5 5 5 5 TPR repeat TPR_2 PF07719.12 KUM60278.1 - 2.3e-43 142.6 18.2 5.9e-06 25.8 0.0 10.4 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_8 PF13181.1 KUM60278.1 - 1.5e-36 121.4 18.0 1.3e-05 24.5 0.5 9.5 7 1 2 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 KUM60278.1 - 2.2e-29 101.2 16.7 2.4e-07 30.5 0.1 6.9 3 2 4 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 KUM60278.1 - 6.5e-29 99.9 13.1 3.3e-07 30.7 0.1 6.4 4 2 1 6 6 5 5 Tetratricopeptide repeat TPR_17 PF13431.1 KUM60278.1 - 1.5e-27 93.4 17.2 7.9e-05 22.5 0.1 9.6 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 KUM60278.1 - 2.9e-22 78.7 12.2 3.7e-05 23.9 0.0 6.5 3 3 3 6 6 6 6 Tetratricopeptide repeat TPR_14 PF13428.1 KUM60278.1 - 3.6e-22 76.8 12.5 0.00038 20.8 0.0 9.2 4 2 6 10 10 10 6 Tetratricopeptide repeat TPR_7 PF13176.1 KUM60278.1 - 2.5e-20 70.5 8.5 0.0018 17.9 0.0 9.2 8 2 1 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.1 KUM60278.1 - 5e-19 67.3 14.7 0.0044 17.3 0.0 9.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.1 KUM60278.1 - 6.7e-15 54.6 5.1 0.0062 16.3 0.0 6.4 2 2 5 7 7 7 5 Tetratricopeptide repeat Apc3 PF12895.2 KUM60278.1 - 1.4e-12 47.6 10.0 3.9e-08 33.3 0.9 4.2 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KUM60278.1 - 7.8e-08 31.6 5.7 0.00017 20.7 2.2 4.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_21 PF09976.4 KUM60278.1 - 0.0002 21.3 4.6 0.17 11.8 0.0 3.9 3 1 1 4 4 3 2 Tetratricopeptide repeat DUF2225 PF09986.4 KUM60278.1 - 0.00058 19.3 3.5 0.63 9.4 0.0 2.9 2 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_20 PF14561.1 KUM60278.1 - 0.0035 17.4 0.1 1.8 8.6 0.0 4.1 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 KUM60278.1 - 0.0093 15.8 3.3 17 5.5 0.1 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat Rapsyn_N PF10579.4 KUM60278.1 - 0.11 12.2 0.6 3.1 7.6 0.1 2.8 2 1 1 3 3 3 0 Rapsyn N-terminal myristoylation and linker region DnaJ-X PF14308.1 KUM60278.1 - 0.13 11.5 0.1 0.25 10.6 0.1 1.4 1 0 0 1 1 1 0 X-domain of DnaJ-containing Nro1 PF12753.2 KUM60278.1 - 0.27 10.1 2.3 1 8.2 0.6 2.1 2 0 0 2 2 2 0 Nuclear pore complex subunit Nro1 MIT PF04212.13 KUM60278.1 - 0.27 11.1 16.0 0.78 9.6 0.5 5.1 5 1 0 5 5 4 0 MIT (microtubule interacting and transport) domain ChAPs PF09295.5 KUM60278.1 - 0.34 9.6 2.0 5.1 5.7 0.1 2.7 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) BTAD PF03704.12 KUM60278.1 - 1.8 8.8 12.0 3.2 8.0 0.0 3.8 4 0 0 4 4 3 0 Bacterial transcriptional activator domain Exo70 PF03081.10 KUM60279.1 - 4.6e-73 246.1 0.0 1e-72 245.0 0.0 1.5 2 0 0 2 2 2 1 Exo70 exocyst complex subunit NPV_P10 PF05531.7 KUM60279.1 - 0.0091 16.2 2.7 0.45 10.8 0.0 4.0 3 1 0 3 3 3 1 Nucleopolyhedrovirus P10 protein BLYB PF05289.6 KUM60279.1 - 0.22 11.3 1.8 62 3.4 0.1 3.7 3 1 1 4 4 4 0 Borrelia hemolysin accessory protein Lyase_1 PF00206.15 KUM60280.1 - 1.3e-21 77.1 0.0 3e-21 75.9 0.0 1.5 2 0 0 2 2 2 1 Lyase ADSL_C PF10397.4 KUM60280.1 - 9.4e-15 54.3 1.0 6.7e-14 51.6 0.0 2.6 3 0 0 3 3 3 1 Adenylosuccinate lyase C-terminus DUF2189 PF09955.4 KUM60281.1 - 0.092 12.6 0.2 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2189) BCDHK_Adom3 PF10436.4 KUM60282.1 - 3e-70 234.9 0.0 4.1e-70 234.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KUM60282.1 - 1.3e-17 63.5 0.0 2.8e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KUM60282.1 - 0.018 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Crust_neurohorm PF01147.12 KUM60282.1 - 0.099 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family CamS PF07537.6 KUM60282.1 - 0.11 11.4 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 CamS sex pheromone cAM373 precursor SKN1 PF03935.10 KUM60284.1 - 1.3e-222 739.4 0.1 1.5e-222 739.2 0.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) AflR PF08493.5 KUM60285.1 - 0.12 11.3 2.0 0.14 11.1 1.4 1.3 1 1 0 1 1 1 0 Aflatoxin regulatory protein Ribosomal_L3 PF00297.17 KUM60286.1 - 3.9e-119 396.8 7.8 4.8e-119 396.5 5.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 DSPc PF00782.15 KUM60287.1 - 1.7e-10 40.6 0.0 3.3e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KUM60287.1 - 2.7e-06 26.8 0.0 4.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KUM60287.1 - 0.0079 16.4 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KUM60287.1 - 0.027 14.5 0.0 0.065 13.2 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate EGF_alliinase PF04863.8 KUM60287.1 - 0.048 13.6 0.2 0.21 11.5 0.0 2.1 2 0 0 2 2 2 0 Alliinase EGF-like domain CDKN3 PF05706.7 KUM60287.1 - 0.19 11.1 0.1 0.48 9.8 0.1 1.6 1 1 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PLA2_B PF01735.13 KUM60288.1 - 3.8e-27 94.6 0.0 1.5e-26 92.6 0.0 1.8 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Foamy_BEL PF03274.9 KUM60288.1 - 0.045 12.9 0.1 0.086 12.0 0.1 1.3 1 0 0 1 1 1 0 Foamy virus BEL 1/2 protein RIC3 PF15361.1 KUM60289.1 - 0.08 13.1 0.0 0.25 11.5 0.0 1.8 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Med18 PF09637.5 KUM60290.1 - 1.1e-65 221.6 0.0 1.2e-65 221.5 0.0 1.0 1 0 0 1 1 1 1 Med18 protein NAD_binding_4 PF07993.7 KUM60291.1 - 2.6e-39 134.6 0.0 4.6e-39 133.8 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KUM60291.1 - 1.2e-29 103.0 0.0 1.8e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KUM60291.1 - 1.2e-10 41.2 0.0 2.2e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KUM60291.1 - 1.3e-05 25.3 0.0 4.4e-05 23.6 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 KUM60291.1 - 0.0065 15.2 0.0 0.086 11.5 0.0 2.5 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_47 PF01532.15 KUM60293.1 - 2.3e-158 527.6 0.1 2.7e-158 527.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Peptidase_M20 PF01546.23 KUM60294.1 - 2.7e-21 75.9 0.1 3.9e-21 75.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KUM60294.1 - 1.4e-16 60.1 0.1 2.7e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain RNA_pol_Rpb1_R PF05001.8 KUM60294.1 - 2 8.7 8.4 1.2 9.4 0.3 3.0 2 0 0 2 2 2 0 RNA polymerase Rpb1 C-terminal repeat AAA PF00004.24 KUM60295.1 - 1.5e-42 144.9 0.0 2.4e-42 144.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KUM60295.1 - 1.8e-07 31.2 0.1 7.1e-06 26.1 0.0 2.5 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.9 KUM60295.1 - 3.9e-06 26.6 0.0 6.4e-05 22.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KUM60295.1 - 6.8e-06 26.1 0.0 2.4e-05 24.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KUM60295.1 - 1.2e-05 25.3 0.0 0.0042 17.2 0.0 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 KUM60295.1 - 1.7e-05 24.0 0.0 3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 KUM60295.1 - 0.00035 19.5 0.0 0.00086 18.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 KUM60295.1 - 0.00078 19.1 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 KUM60295.1 - 0.0025 16.6 0.3 0.0052 15.5 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus AAA_17 PF13207.1 KUM60295.1 - 0.0035 18.1 0.1 0.011 16.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KUM60295.1 - 0.0039 16.6 0.0 0.0077 15.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 KUM60295.1 - 0.0043 16.9 0.0 0.0098 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KUM60295.1 - 0.0067 16.5 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.16 KUM60295.1 - 0.0068 15.5 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KUM60295.1 - 0.0079 15.6 0.1 0.043 13.2 0.1 2.1 1 1 1 2 2 2 1 AAA domain Sigma54_activat PF00158.21 KUM60295.1 - 0.01 15.3 0.0 0.032 13.7 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 KUM60295.1 - 0.011 14.9 0.0 0.023 13.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 KUM60295.1 - 0.012 15.9 0.0 0.029 14.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KUM60295.1 - 0.013 15.1 0.0 0.029 13.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KUM60295.1 - 0.016 15.0 0.0 0.048 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KUM60295.1 - 0.024 14.2 0.1 0.062 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 KUM60295.1 - 0.036 14.1 0.0 0.09 12.8 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 KUM60295.1 - 0.039 13.9 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KUM60295.1 - 0.042 12.9 0.0 0.14 11.2 0.0 1.9 2 0 0 2 2 2 0 KaiC eIF-1a PF01176.14 KUM60295.1 - 0.044 13.2 0.1 0.082 12.3 0.1 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 PhoH PF02562.11 KUM60295.1 - 0.051 12.8 0.0 0.091 11.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 KUM60295.1 - 0.065 12.8 0.0 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_11 PF13086.1 KUM60295.1 - 0.072 12.6 0.0 0.39 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KUM60295.1 - 0.11 12.1 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 KUM60295.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UPF0079 PF02367.12 KUM60295.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 KUM60295.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 HLH PF00010.21 KUM60296.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain eIF3_subunit PF08597.5 KUM60297.1 - 3.4e-70 236.3 24.3 3.8e-70 236.2 16.9 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit ATC_hydrolase PF14196.1 KUM60297.1 - 0.29 11.5 0.1 0.29 11.5 0.0 2.2 2 0 0 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Nop53 PF07767.6 KUM60297.1 - 0.72 8.7 27.4 0.053 12.5 13.0 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) RepB-RCR_reg PF10723.4 KUM60297.1 - 1.6 8.4 8.8 7.7 6.3 0.4 2.8 2 1 1 3 3 3 0 Replication regulatory protein RepB FNIP_N PF14636.1 KUM60297.1 - 2.2 8.7 7.6 0.35 11.3 1.3 2.1 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus IRF PF00605.12 KUM60297.1 - 2.3 8.0 6.1 0.52 10.1 1.1 2.0 2 0 0 2 2 2 0 Interferon regulatory factor transcription factor Dehalogenase PF13486.1 KUM60297.1 - 2.5 7.4 7.1 0.93 8.8 0.3 2.0 2 0 0 2 2 2 0 Reductive dehalogenase subunit SpoVR PF04293.8 KUM60297.1 - 9.4 4.4 7.5 16 3.6 5.2 1.3 1 0 0 1 1 1 0 SpoVR like protein Enolase_C PF00113.17 KUM60298.1 - 1.7e-152 506.5 0.0 2.2e-152 506.1 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KUM60298.1 - 5.4e-57 191.3 0.5 1.6e-56 189.8 0.1 1.9 2 0 0 2 2 2 1 Enolase, N-terminal domain MAAL_C PF07476.6 KUM60298.1 - 0.044 12.6 0.2 1.2 8.0 0.0 2.5 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 KUM60298.1 - 0.045 14.2 0.0 0.12 12.9 0.0 1.8 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain PNK3P PF08645.6 KUM60300.1 - 4.1e-54 182.3 0.0 7.2e-54 181.5 0.0 1.4 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 KUM60300.1 - 2.9e-32 111.5 0.0 3e-31 108.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 KUM60300.1 - 2e-06 27.1 1.9 0.016 14.4 0.0 2.6 2 1 1 3 3 3 2 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 KUM60300.1 - 0.076 12.1 0.0 0.25 10.4 0.0 1.8 1 1 1 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.13 KUM60300.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family HAD_2 PF13419.1 KUM60300.1 - 0.13 12.5 0.1 7.1 6.8 0.0 2.9 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Pkinase PF00069.20 KUM60301.1 - 5.6e-37 127.3 0.0 7.1e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM60301.1 - 1.7e-14 53.5 0.0 2.2e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KUM60301.1 - 0.017 14.8 0.0 0.56 9.9 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family RGS PF00615.14 KUM60302.1 - 1.7e-13 50.7 0.0 3e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain KOW PF00467.24 KUM60303.1 - 0.0021 17.6 1.0 0.0038 16.8 0.7 1.4 1 0 0 1 1 1 1 KOW motif Rtt106 PF08512.7 KUM60304.1 - 1.1e-24 86.2 0.1 3e-24 84.8 0.0 1.8 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Cwf_Cwc_15 PF04889.7 KUM60304.1 - 6.5 6.3 18.7 13 5.4 13.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2638 PF10937.3 KUM60305.1 - 2.8e-39 134.6 0.2 3.2e-39 134.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) DUF647 PF04884.9 KUM60306.1 - 2.2e-12 46.7 1.0 3.7e-12 45.9 0.7 1.4 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF647 PF04884.9 KUM60307.1 - 1.6e-73 247.0 0.1 2e-73 246.7 0.1 1.0 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Ras PF00071.17 KUM60309.1 - 6.4e-56 188.2 0.0 8.2e-56 187.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KUM60309.1 - 2.2e-15 57.1 0.0 3.3e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KUM60309.1 - 3e-07 29.8 0.0 4.6e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KUM60309.1 - 0.00072 18.8 0.0 0.001 18.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 KUM60309.1 - 0.0014 18.0 0.0 0.0059 16.0 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KUM60309.1 - 0.013 14.6 0.0 0.023 13.8 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region 14-3-3 PF00244.15 KUM60310.1 - 3e-114 380.0 0.2 3.7e-114 379.6 0.2 1.1 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 KUM60310.1 - 0.013 15.3 0.3 2.5 8.1 0.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF837 PF05769.6 KUM60310.1 - 0.04 13.4 0.6 6 6.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF837) Beach PF02138.13 KUM60312.1 - 3.2e-108 361.2 0.0 6.5e-108 360.2 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 KUM60312.1 - 7.4e-13 48.2 0.0 1.6e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 KUM60312.1 - 2.2e-09 36.8 2.4 0.00015 21.5 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Laminin_G_3 PF13385.1 KUM60312.1 - 5.1e-09 36.5 0.0 1.2e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Aldo_ket_red PF00248.16 KUM60313.1 - 1.1e-61 208.2 0.0 1.4e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family UQ_con PF00179.21 KUM60314.1 - 8.8e-37 125.6 0.2 3e-35 120.6 0.1 2.1 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme MmgE_PrpD PF03972.9 KUM60315.1 - 2.4e-68 230.3 0.0 2.8e-68 230.1 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family ABC_tran PF00005.22 KUM60317.1 - 1.1e-54 184.5 0.1 1.3e-31 109.6 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KUM60317.1 - 1.1e-43 149.6 26.7 4.6e-27 95.1 1.3 4.1 4 0 0 4 4 4 3 ABC transporter transmembrane region AAA_21 PF13304.1 KUM60317.1 - 1.5e-10 41.5 0.2 0.0042 17.0 0.0 3.8 4 0 0 4 4 3 2 AAA domain SMC_N PF02463.14 KUM60317.1 - 3.3e-08 33.0 4.9 0.0056 15.9 0.3 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KUM60317.1 - 1.1e-07 32.3 0.7 7.5e-05 23.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KUM60317.1 - 3.5e-06 26.5 0.0 0.092 12.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KUM60317.1 - 2.2e-05 24.5 1.2 1.8 8.6 0.1 3.6 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 KUM60317.1 - 4.6e-05 22.6 0.1 0.074 12.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.12 KUM60317.1 - 4.6e-05 23.3 1.5 0.038 13.7 0.1 2.7 2 0 0 2 2 2 2 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 KUM60317.1 - 0.00012 22.0 0.2 0.19 11.6 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase T2SE PF00437.15 KUM60317.1 - 0.00017 20.6 0.0 0.017 14.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_17 PF13207.1 KUM60317.1 - 0.00017 22.4 0.1 1.1 10.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KUM60317.1 - 0.00028 20.3 0.0 0.56 9.5 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Miro PF08477.8 KUM60317.1 - 0.0003 21.2 0.2 0.95 9.9 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_10 PF12846.2 KUM60317.1 - 0.00033 20.1 0.2 1 8.7 0.0 2.7 3 0 0 3 3 2 2 AAA-like domain AAA_16 PF13191.1 KUM60317.1 - 0.00037 20.5 2.2 0.96 9.3 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KUM60317.1 - 0.0004 19.8 3.6 0.38 10.3 0.0 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KUM60317.1 - 0.00066 18.8 2.5 0.2 10.7 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.1 KUM60317.1 - 0.0028 17.9 0.7 2.2 8.5 0.0 3.2 3 0 0 3 3 2 1 AAA domain MobB PF03205.9 KUM60317.1 - 0.0052 16.4 0.5 0.6 9.8 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 KUM60317.1 - 0.014 14.9 0.0 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.24 KUM60317.1 - 0.029 14.5 0.7 3 8.0 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KUM60317.1 - 0.044 13.6 0.4 2.4 8.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 KUM60317.1 - 0.051 13.3 1.4 2.3 7.9 0.0 2.7 2 0 0 2 2 2 0 Dynamin family TrwB_AAD_bind PF10412.4 KUM60317.1 - 0.085 11.4 1.9 4.1 5.9 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATP-synt_ab PF00006.20 KUM60317.1 - 0.095 12.1 0.1 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain TIP49 PF06068.8 KUM60317.1 - 0.12 11.0 0.9 7.2 5.2 0.1 2.4 2 0 0 2 2 2 0 TIP49 C-terminus NACHT PF05729.7 KUM60317.1 - 0.14 11.8 2.6 1.4 8.5 0.1 2.6 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.4 KUM60317.1 - 0.16 11.4 0.7 7.7 5.9 0.1 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 KUM60317.1 - 0.17 11.4 2.0 25 4.3 0.3 3.4 3 1 0 3 3 3 0 AAA domain Pox_A32 PF04665.7 KUM60317.1 - 0.26 10.5 1.2 4.2 6.6 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Arch_ATPase PF01637.13 KUM60317.1 - 0.28 10.8 0.6 0.71 9.5 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase AAA_15 PF13175.1 KUM60317.1 - 0.37 9.7 0.0 0.94 8.4 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.14 KUM60317.1 - 0.93 8.9 5.6 0.85 9.0 0.3 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AMP-binding PF00501.23 KUM60319.1 - 7.8e-158 525.2 0.0 1.8e-81 273.7 0.0 3.0 3 0 0 3 3 3 2 AMP-binding enzyme Condensation PF00668.15 KUM60319.1 - 1.8e-114 381.6 0.0 6.1e-36 123.8 0.0 4.6 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.20 KUM60319.1 - 2.1e-34 117.5 0.0 6.9e-11 42.2 0.0 5.4 5 0 0 5 5 5 4 Phosphopantetheine attachment site UPF0118 PF01594.11 KUM60319.1 - 2.4 7.0 0.0 4.7 6.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF20 Transaldolase PF00923.14 KUM60321.1 - 1.6e-93 312.9 0.2 1.8e-93 312.7 0.2 1.0 1 0 0 1 1 1 1 Transaldolase Peptidase_S8 PF00082.17 KUM60322.1 - 4.3e-55 186.8 12.1 6.7e-55 186.2 8.4 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KUM60322.1 - 2.8e-20 72.6 0.3 5.3e-20 71.7 0.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 FA_hydroxylase PF04116.8 KUM60323.1 - 1.7e-13 50.9 12.8 1.7e-13 50.9 8.8 2.6 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily CRAL_TRIO PF00650.15 KUM60324.1 - 1.3e-24 86.5 0.0 1.7e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KUM60324.1 - 1.3e-11 44.4 0.4 3.5e-11 43.0 0.3 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain SNase PF00565.12 KUM60325.1 - 8.5e-74 244.7 0.0 1.2e-23 83.4 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 KUM60325.1 - 4.6e-23 81.3 0.0 3.4e-22 78.5 0.0 2.4 3 0 0 3 3 3 1 Tudor domain SMN PF06003.7 KUM60325.1 - 4.9e-05 22.5 0.0 9.3e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Sod_Cu PF00080.15 KUM60326.1 - 2.6e-44 150.8 4.0 3e-44 150.6 2.8 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) RVT_2 PF07727.9 KUM60327.1 - 8.7e-15 54.3 0.0 1.2e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LAT PF15234.1 KUM60328.1 - 0.033 13.6 0.1 0.041 13.3 0.1 1.3 1 0 0 1 1 1 0 Linker for activation of T-cells dUTPase PF00692.14 KUM60329.1 - 0.14 11.5 0.1 0.72 9.3 0.0 1.9 1 1 0 1 1 1 0 dUTPase DUF1620 PF07774.8 KUM60330.1 - 1.5e-75 253.1 0.0 4.3e-75 251.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 KUM60330.1 - 4.1e-28 98.4 22.5 1.3e-23 83.6 2.2 3.1 3 1 1 4 4 4 3 PQQ-like domain PQQ PF01011.16 KUM60330.1 - 2.1e-07 30.1 0.1 0.32 10.6 0.1 5.2 5 0 0 5 5 5 3 PQQ enzyme repeat PQQ_3 PF13570.1 KUM60330.1 - 0.41 10.9 0.0 0.41 10.9 0.0 4.7 6 1 0 6 6 6 0 PQQ-like domain MFS_1 PF07690.11 KUM60332.1 - 2.1e-41 141.8 41.9 2.4e-41 141.6 24.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM60332.1 - 1.9e-09 36.6 10.6 1.9e-09 36.6 7.3 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter ATG22 PF11700.3 KUM60333.1 - 4.8e-112 374.8 18.4 5.5e-112 374.6 12.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KUM60333.1 - 3.1e-10 39.2 41.8 3.4e-07 29.3 1.7 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily COX16 PF14138.1 KUM60333.1 - 0.034 14.2 0.5 6.6 6.9 0.0 2.6 3 0 0 3 3 3 0 Cytochrome c oxidase assembly protein COX16 DUF3697 PF12478.3 KUM60334.1 - 0.072 12.7 0.4 0.072 12.7 0.3 3.1 3 0 0 3 3 3 0 Ubiquitin-associated protein 2 Oxysterol_BP PF01237.13 KUM60335.1 - 6e-89 297.9 0.1 7.1e-89 297.7 0.1 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein NAD_binding_11 PF14833.1 KUM60336.1 - 7e-43 145.5 1.1 7e-25 87.4 0.0 2.6 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 KUM60336.1 - 3.9e-34 117.8 0.3 1e-33 116.4 0.2 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1537 PF07005.6 KUM60336.1 - 3.2e-15 56.4 1.4 7.6e-15 55.1 0.0 2.2 3 0 0 3 3 3 1 Protein of unknown function, DUF1537 UDPG_MGDP_dh_N PF03721.9 KUM60336.1 - 0.0003 20.2 0.0 0.12 11.7 0.0 2.6 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 KUM60336.1 - 0.00045 19.9 0.3 0.00087 18.9 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KUM60336.1 - 0.0014 19.0 0.3 0.012 16.0 0.1 2.6 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Gp_dh_C PF02800.15 KUM60336.1 - 0.016 14.6 0.1 0.038 13.4 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain AlaDh_PNT_C PF01262.16 KUM60336.1 - 0.053 13.0 0.2 0.094 12.2 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 KUM60337.1 - 5.7e-22 78.7 0.0 1.4e-21 77.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KUM60337.1 - 1.6e-13 49.7 0.0 7.4e-12 44.2 0.0 2.6 1 1 1 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KUM60337.1 - 4.7e-07 29.0 0.0 0.0032 16.4 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KUM60337.1 - 2.1e-06 27.6 0.0 5.5e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KUM60337.1 - 1.4e-05 25.0 0.0 0.00019 21.3 0.0 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM60337.1 - 0.012 15.4 0.0 0.51 10.0 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF3337 PF11816.3 KUM60337.1 - 0.14 11.4 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) zf-H2C2_2 PF13465.1 KUM60338.1 - 4.2e-07 29.9 4.5 0.0056 16.9 0.8 2.3 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 KUM60338.1 - 1.3e-06 28.1 8.3 6.5e-05 22.6 0.3 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KUM60338.1 - 1.5e-05 24.9 15.9 3.6e-05 23.7 1.2 2.6 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 KUM60338.1 - 2.1e-05 24.5 1.6 2.1e-05 24.5 1.1 2.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type C1_1 PF00130.17 KUM60338.1 - 0.00093 18.8 0.8 0.0015 18.1 0.5 1.4 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-H2C2_5 PF13909.1 KUM60338.1 - 0.0049 17.0 0.5 0.0049 17.0 0.3 2.1 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-Di19 PF05605.7 KUM60338.1 - 0.0073 16.4 1.8 0.01 15.9 1.3 1.2 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding RRN7 PF11781.3 KUM60338.1 - 0.0081 15.6 4.4 0.64 9.5 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2H2_jaz PF12171.3 KUM60338.1 - 0.052 13.7 0.1 0.052 13.7 0.0 1.8 2 0 0 2 2 1 0 Zinc-finger double-stranded RNA-binding Mu-like_Com PF10122.4 KUM60338.1 - 0.068 12.2 3.6 1.5 7.9 0.0 2.4 1 1 2 3 3 3 0 Mu-like prophage protein Com Cytochrom_c3_2 PF14537.1 KUM60338.1 - 0.073 13.4 3.1 0.089 13.1 2.1 1.2 1 0 0 1 1 1 0 Cytochrome c3 zinc_ribbon_4 PF13717.1 KUM60338.1 - 0.26 10.9 3.6 1.3 8.7 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KUM60338.1 - 0.32 10.6 3.9 1.3 8.6 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain IBR PF01485.16 KUM60338.1 - 1.2 9.1 6.4 2.2 8.2 4.4 1.5 1 1 0 1 1 1 0 IBR domain C1_4 PF07975.7 KUM60338.1 - 2.7 8.0 6.1 19 5.3 4.3 2.0 1 1 1 2 2 2 0 TFIIH C1-like domain LIM PF00412.17 KUM60338.1 - 5.8 7.0 7.3 21 5.2 0.3 2.1 1 1 1 2 2 2 0 LIM domain zf-MYND PF01753.13 KUM60338.1 - 8.4 6.3 9.9 9.2 6.2 0.4 2.3 1 1 1 2 2 2 0 MYND finger Glyco_hydro_3 PF00933.16 KUM60340.1 - 1.3e-53 181.9 0.0 1.9e-53 181.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.19 KUM60340.1 - 8.2e-19 67.4 0.0 3.9e-09 36.4 0.0 3.0 3 0 0 3 3 3 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KUM60340.1 - 5.8e-17 61.6 0.0 1.1e-07 31.8 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KUM60340.1 - 1.1e-10 41.6 0.0 9.4e-08 32.1 0.0 2.7 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KUM60340.1 - 4.5e-07 29.7 0.0 0.0092 15.8 0.0 2.6 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 KUM60340.1 - 4.4e-05 23.4 0.0 0.34 10.8 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.17 KUM60340.1 - 0.0015 18.0 0.0 0.0039 16.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain FR47 PF08445.5 KUM60340.1 - 0.0028 17.3 0.0 0.089 12.5 0.0 2.5 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.1 KUM60340.1 - 0.04 13.8 0.1 16 5.4 0.0 2.9 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase DHDPS PF00701.17 KUM60342.1 - 4.7e-09 35.2 0.0 5.6e-09 35.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MFS_1 PF07690.11 KUM60343.1 - 2.1e-34 118.8 25.6 3e-34 118.2 17.6 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Hydantoinase_B PF02538.9 KUM60344.1 - 7.1e-193 641.5 0.0 8.7e-193 641.3 0.0 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KUM60345.1 - 8.1e-90 300.8 0.0 1.5e-89 299.9 0.0 1.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KUM60345.1 - 2.3e-55 186.8 0.2 5.6e-53 179.0 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region HasA PF06438.7 KUM60345.1 - 0.053 12.9 0.0 2.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Heme-binding protein A (HasA) NAD_binding_2 PF03446.10 KUM60346.1 - 2.6e-25 89.1 0.0 4.1e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KUM60346.1 - 1.4e-10 41.3 0.0 2.2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KUM60346.1 - 0.023 15.0 0.0 0.079 13.3 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DHDPS PF00701.17 KUM60347.1 - 2e-25 89.0 0.0 2.5e-25 88.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PGM_PMM_I PF02878.11 KUM60348.1 - 9.4e-32 109.3 0.1 1.4e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 KUM60348.1 - 7.6e-26 90.3 0.0 1.3e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 KUM60348.1 - 1.5e-16 60.6 0.1 3.5e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KUM60348.1 - 2.1e-09 37.2 0.0 5.1e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain GFO_IDH_MocA PF01408.17 KUM60349.1 - 3.5e-12 46.9 0.0 1e-11 45.4 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KUM60349.1 - 9.2e-05 22.2 0.0 0.00021 21.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Sugar_tr PF00083.19 KUM60350.1 - 6.5e-78 262.3 24.5 9.2e-78 261.8 17.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM60350.1 - 1.8e-26 92.6 30.5 1.8e-26 92.6 21.2 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM60350.1 - 0.00055 18.2 4.3 0.00099 17.4 3.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) K_oxygenase PF13434.1 KUM60351.1 - 1.2e-15 57.3 0.0 4e-10 39.1 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KUM60351.1 - 2.1e-12 47.5 0.2 4.2e-05 23.6 0.0 3.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM60351.1 - 1.3e-06 28.3 0.0 0.043 13.5 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding Shikimate_DH PF01488.15 KUM60351.1 - 0.00026 21.1 0.0 0.29 11.2 0.0 2.6 3 0 0 3 3 2 2 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 KUM60351.1 - 0.00089 19.1 0.0 0.11 12.3 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KUM60351.1 - 0.0011 17.9 0.0 0.0031 16.4 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.17 KUM60351.1 - 0.002 17.0 0.2 0.15 10.8 0.1 2.4 2 1 1 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.9 KUM60351.1 - 0.0024 16.4 0.0 0.082 11.3 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 KUM60351.1 - 0.0027 16.8 0.0 0.02 13.9 0.0 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 KUM60351.1 - 0.0086 16.0 0.6 0.12 12.3 0.0 2.9 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KUM60351.1 - 0.011 14.6 0.0 0.11 11.3 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 KUM60351.1 - 0.018 14.0 0.3 0.068 12.2 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.19 KUM60351.1 - 0.02 13.8 2.7 0.87 8.4 0.0 3.1 3 1 0 3 3 3 0 FAD dependent oxidoreductase Kelch_6 PF13964.1 KUM60351.1 - 0.047 13.8 0.2 0.24 11.6 0.2 2.2 1 0 0 1 1 1 0 Kelch motif Herpes_capsid PF06112.6 KUM60351.1 - 0.13 12.3 3.7 0.26 11.2 2.5 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein TrkA_N PF02254.13 KUM60351.1 - 0.2 11.6 0.0 0.6 10.1 0.0 1.8 2 0 0 2 2 1 0 TrkA-N domain GST_N_3 PF13417.1 KUM60352.1 - 1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KUM60352.1 - 5.6e-12 45.6 0.0 1.1e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KUM60352.1 - 1.3e-10 41.0 0.0 2.6e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Sugar_tr PF00083.19 KUM60353.1 - 1.1e-87 294.5 24.9 1.3e-87 294.2 17.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM60353.1 - 3.5e-17 62.1 60.1 1.2e-13 50.4 18.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1451 PF07295.6 KUM60353.1 - 0.22 11.2 0.1 0.36 10.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) RNase_T PF00929.19 KUM60354.1 - 2.2e-25 89.8 0.0 2.5e-25 89.6 0.0 1.0 1 0 0 1 1 1 1 Exonuclease Cwf_Cwc_15 PF04889.7 KUM60355.1 - 1.7 8.2 16.0 0.6 9.7 1.5 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF1903 PF08991.5 KUM60357.1 - 0.0095 16.0 1.5 0.015 15.3 1.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 KUM60357.1 - 0.017 15.0 1.4 0.034 14.0 1.0 1.6 1 0 0 1 1 1 0 CHCH domain NatB_MDM20 PF09797.4 KUM60358.1 - 2.1e-74 250.4 0.1 4.7e-74 249.2 0.1 1.5 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.1 KUM60358.1 - 0.0032 17.7 3.8 0.81 10.0 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_10 PF12846.2 KUM60358.1 - 0.042 13.2 0.5 0.38 10.1 0.1 2.3 2 0 0 2 2 2 0 AAA-like domain TPR_16 PF13432.1 KUM60358.1 - 0.045 14.4 1.8 6.6 7.5 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Lactamase_B PF00753.22 KUM60359.1 - 1.5e-11 44.3 0.0 2e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KUM60359.1 - 2.5e-06 27.1 0.1 3.2e-06 26.8 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KUM60359.1 - 0.0012 18.5 0.0 0.0014 18.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain N6-adenineMlase PF10237.4 KUM60359.1 - 0.049 13.2 0.0 0.049 13.2 0.0 1.1 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase Lactamase_B PF00753.22 KUM60360.1 - 0.019 14.6 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily GH-E PF14410.1 KUM60360.1 - 0.11 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Glyco_hydro_28 PF00295.12 KUM60361.1 - 5.3e-29 101.2 5.0 6.8e-29 100.8 3.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.2 KUM60361.1 - 2.8e-11 43.9 5.6 1.7e-10 41.4 3.5 2.3 1 1 1 2 2 2 1 Pectate lyase superfamily protein Ank_2 PF12796.2 KUM60362.1 - 1.3e-46 156.8 8.2 1.5e-08 34.8 0.0 7.8 4 2 3 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KUM60362.1 - 1.1e-33 115.0 11.0 1.5e-05 25.3 0.0 9.4 6 2 3 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.25 KUM60362.1 - 1.6e-29 100.1 14.5 8.8e-07 28.4 0.0 11.9 12 0 0 12 12 12 7 Ankyrin repeat Ank_5 PF13857.1 KUM60362.1 - 2.6e-29 100.5 13.7 0.00016 21.7 0.0 10.0 7 4 3 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM60362.1 - 1.1e-19 68.5 10.8 2.4e-05 24.1 0.0 11.7 14 0 0 14 14 14 3 Ankyrin repeat PNP_UDP_1 PF01048.15 KUM60362.1 - 5.7e-10 38.5 0.2 3.3e-09 36.0 0.2 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_22 PF13401.1 KUM60362.1 - 0.0012 19.0 0.3 0.018 15.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 KUM60362.1 - 0.0037 16.9 0.0 0.012 15.2 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KUM60362.1 - 0.0075 16.2 0.1 0.16 11.9 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain Kinesin PF00225.18 KUM60362.1 - 0.21 10.2 0.0 0.47 9.0 0.0 1.5 1 0 0 1 1 1 0 Kinesin motor domain Peptidase_S41 PF03572.13 KUM60363.1 - 1.5e-05 24.5 0.0 2.6e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 Peptidase family S41 MFS_1 PF07690.11 KUM60364.1 - 2.8e-29 101.9 42.0 2.8e-29 101.9 29.1 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily G-patch_2 PF12656.2 KUM60364.1 - 2.3e-28 97.8 0.2 1.4e-27 95.3 0.0 2.5 2 0 0 2 2 2 1 DExH-box splicing factor binding site G-patch PF01585.18 KUM60364.1 - 0.0031 17.2 0.1 0.0092 15.7 0.1 1.9 1 0 0 1 1 1 1 G-patch domain Tmemb_18A PF09771.4 KUM60364.1 - 1.2 9.1 3.3 0.61 10.0 0.1 2.1 2 0 0 2 2 2 0 Transmembrane protein 188 WD40 PF00400.27 KUM60365.1 - 1.7e-79 259.1 27.4 4.7e-10 38.9 0.0 13.3 13 2 0 13 13 13 12 WD domain, G-beta repeat Utp13 PF08625.6 KUM60365.1 - 2e-45 153.9 0.0 3.2e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nucleoporin_N PF08801.6 KUM60365.1 - 7.6e-05 21.6 5.3 2.4 6.8 0.0 5.5 2 2 1 5 5 5 3 Nup133 N terminal like DUF3312 PF11768.3 KUM60365.1 - 0.045 11.9 0.0 0.15 10.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) FAD-oxidase_C PF02913.14 KUM60367.1 - 2.1e-34 118.9 0.0 2.9e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KUM60367.1 - 5e-25 87.5 0.1 8.1e-25 86.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain TPR_12 PF13424.1 KUM60368.1 - 4.9e-126 410.9 16.7 1.7e-19 69.4 0.0 6.2 1 1 7 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.1 KUM60368.1 - 1.3e-99 323.6 14.7 9.2e-14 50.8 0.1 9.7 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_11 PF13414.1 KUM60368.1 - 1.5e-31 107.8 10.9 5e-08 32.4 0.2 6.3 2 2 5 7 7 7 7 TPR repeat TPR_1 PF00515.23 KUM60368.1 - 2.1e-26 90.3 18.2 0.00042 19.8 0.1 9.3 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_7 PF13176.1 KUM60368.1 - 1.6e-25 86.8 5.7 0.014 15.1 0.0 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat Patatin PF01734.17 KUM60368.1 - 2e-23 83.4 0.0 4.4e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_17 PF13431.1 KUM60368.1 - 1.5e-17 62.2 0.0 2.3 8.6 0.0 8.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 KUM60368.1 - 1.4e-14 54.2 12.2 0.00027 21.5 0.6 6.8 2 1 7 9 9 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 KUM60368.1 - 1e-12 46.8 16.9 0.46 10.5 0.1 9.5 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_4 PF07721.9 KUM60368.1 - 1.4e-10 40.5 0.0 8.4 7.1 0.0 7.5 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF1925 PF09094.6 KUM60368.1 - 2.7e-10 40.0 0.0 7.6 6.5 0.0 7.6 8 0 0 8 8 7 0 Domain of unknown function (DUF1925) NB-ARC PF00931.17 KUM60368.1 - 2e-07 30.1 0.0 3.5e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Apc3 PF12895.2 KUM60368.1 - 3.7e-07 30.2 0.0 1.2 9.2 0.0 5.1 1 1 5 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 AAA_16 PF13191.1 KUM60368.1 - 6.2e-07 29.5 0.3 6.4e-06 26.2 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KUM60368.1 - 1.2e-06 28.6 0.0 4.3e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain TPR_14 PF13428.1 KUM60368.1 - 1.2e-06 28.5 14.3 1.9 9.3 0.1 7.9 6 2 2 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 KUM60368.1 - 3.1e-05 23.4 14.4 6.5 6.7 0.0 8.6 9 0 0 9 9 8 0 Tetratricopeptide repeat NACHT PF05729.7 KUM60368.1 - 4.3e-05 23.2 0.0 0.00011 21.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Rab5-bind PF09311.6 KUM60368.1 - 5.6e-05 23.1 1.0 2.5 7.9 0.0 5.2 1 1 5 6 6 6 1 Rabaptin-like protein TPR_19 PF14559.1 KUM60368.1 - 0.00027 21.2 12.8 0.69 10.2 0.9 6.2 2 1 7 9 9 9 2 Tetratricopeptide repeat Tcf25 PF04910.9 KUM60368.1 - 0.00075 18.5 0.0 6.8 5.5 0.0 4.0 2 2 3 5 5 5 0 Transcriptional repressor TCF25 FTCD PF02971.9 KUM60368.1 - 0.0022 17.6 0.0 34 4.0 0.0 5.1 2 2 3 5 5 5 0 Formiminotransferase domain IstB_IS21 PF01695.12 KUM60368.1 - 0.019 14.3 0.1 0.072 12.5 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein UCH PF00443.24 KUM60372.1 - 8e-21 74.3 0.0 5e-19 68.4 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KUM60372.1 - 1.1e-11 44.7 0.1 2.5e-11 43.5 0.0 1.6 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein DUF2578 PF10843.3 KUM60373.1 - 0.0015 18.2 1.4 0.0025 17.5 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2578) Proteasome PF00227.21 KUM60375.1 - 7.6e-26 90.5 0.0 8.8e-26 90.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit zf-RING_2 PF13639.1 KUM60376.1 - 4.9e-09 35.8 6.8 4.9e-09 35.8 4.7 2.5 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 KUM60376.1 - 5.2e-09 35.6 4.8 5.2e-09 35.6 3.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KUM60376.1 - 6.2e-08 32.3 7.6 6.2e-08 32.3 5.3 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KUM60376.1 - 1.1e-07 31.7 7.3 1.1e-07 31.7 5.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KUM60376.1 - 1.7e-07 30.8 3.6 1.7e-07 30.8 2.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KUM60376.1 - 5.4e-07 29.2 5.8 5.4e-07 29.2 4.0 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KUM60376.1 - 0.00032 20.3 1.8 0.00032 20.3 1.3 1.9 2 0 0 2 2 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 KUM60376.1 - 0.002 17.9 1.0 0.002 17.9 0.7 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KUM60376.1 - 0.0042 17.1 7.5 0.0064 16.5 2.5 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_6 PF14835.1 KUM60376.1 - 0.0092 15.7 3.1 0.0092 15.7 2.2 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein DZR PF12773.2 KUM60376.1 - 0.028 14.2 8.8 2 8.2 3.0 2.5 2 0 0 2 2 2 0 Double zinc ribbon IBR PF01485.16 KUM60376.1 - 2.9 7.8 11.0 35 4.3 5.4 2.9 1 1 1 2 2 2 0 IBR domain zf-RING_4 PF14570.1 KUM60376.1 - 8.1 6.1 14.3 0.035 13.6 2.0 2.6 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain WD40 PF00400.27 KUM60377.1 - 2.8e-30 103.0 18.5 2e-08 33.7 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat CATSPERB PF15149.1 KUM60377.1 - 0.23 9.5 0.0 0.35 9.0 0.0 1.2 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit beta protein family XFP_N PF09364.5 KUM60378.1 - 4.2e-138 460.0 0.0 6.2e-138 459.4 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 KUM60378.1 - 6.1e-68 227.9 0.1 1e-67 227.1 0.0 1.4 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 KUM60378.1 - 4e-67 225.5 0.0 6.1e-67 224.9 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain TPP_enzyme_C PF02775.16 KUM60378.1 - 0.011 15.2 0.1 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF1842 PF08896.5 KUM60378.1 - 0.1 12.3 1.3 0.54 10.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1842) Acetate_kinase PF00871.12 KUM60379.1 - 2.3e-94 316.1 0.0 2.7e-94 315.8 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family DUF1464 PF07318.7 KUM60379.1 - 0.085 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) RTA1 PF04479.8 KUM60381.1 - 2.9e-55 187.2 9.6 3.8e-55 186.8 6.7 1.1 1 0 0 1 1 1 1 RTA1 like protein CLU PF13236.1 KUM60382.1 - 2.4e-79 265.8 0.0 5.6e-79 264.6 0.0 1.6 2 0 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.2 KUM60382.1 - 1.5e-52 177.9 0.0 3.9e-52 176.5 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 KUM60382.1 - 1.1e-29 102.2 13.4 2.8e-10 40.0 0.1 4.3 2 1 4 6 6 5 4 Tetratricopeptide repeat CLU_N PF15044.1 KUM60382.1 - 1.7e-27 95.3 0.2 4.9e-27 93.8 0.1 1.9 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.1 KUM60382.1 - 1e-16 60.2 0.1 2e-05 24.3 0.0 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 KUM60382.1 - 1.6e-05 24.4 3.5 0.058 13.0 0.3 3.4 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 KUM60382.1 - 0.00011 21.8 7.1 0.36 10.8 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KUM60382.1 - 0.0047 17.5 0.0 2.2 9.0 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KUM60382.1 - 0.036 13.8 2.6 1.1 9.1 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Hep_59 PF07052.6 KUM60382.1 - 0.037 14.3 1.6 0.14 12.5 1.1 2.0 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 EnY2 PF10163.4 KUM60382.1 - 0.04 13.8 0.4 0.42 10.5 0.0 2.8 3 0 0 3 3 3 0 Transcription factor e(y)2 TPR_17 PF13431.1 KUM60382.1 - 0.22 11.8 3.1 1.1e+02 3.3 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat AAA_16 PF13191.1 KUM60383.1 - 4.5e-05 23.5 0.4 0.0016 18.4 0.3 2.5 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 KUM60383.1 - 0.00077 19.2 0.1 0.0018 18.0 0.1 1.6 1 1 0 1 1 1 1 Archaeal ATPase AAA_5 PF07728.9 KUM60383.1 - 0.07 12.8 0.1 0.35 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KUM60383.1 - 0.15 12.2 0.2 1.3 9.1 0.3 2.4 2 1 0 2 2 2 0 AAA domain NAD_binding_6 PF08030.7 KUM60384.1 - 3.9e-19 69.0 0.0 7.8e-17 61.6 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KUM60384.1 - 2.6e-16 59.3 0.0 2.6e-14 52.9 0.0 2.4 1 1 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KUM60384.1 - 3.6e-14 52.9 11.9 3.6e-14 52.9 8.2 2.6 2 1 0 2 2 2 1 Ferric reductase like transmembrane component DUF4405 PF14358.1 KUM60384.1 - 9.1 6.5 14.9 4.7 7.4 0.6 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) WD40 PF00400.27 KUM60385.1 - 2.6e-43 144.3 9.8 3.4e-08 33.0 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 KUM60385.1 - 1.2e-09 37.7 0.1 2.6e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KUM60385.1 - 0.00026 20.5 0.0 0.00093 18.7 0.0 1.9 2 0 0 2 2 2 1 F-box domain PQQ_2 PF13360.1 KUM60385.1 - 0.00074 19.0 0.3 0.0029 17.0 0.1 2.1 2 1 0 2 2 2 1 PQQ-like domain PQQ PF01011.16 KUM60385.1 - 0.0044 16.4 0.2 4.1 7.1 0.0 3.4 3 0 0 3 3 3 1 PQQ enzyme repeat Nup160 PF11715.3 KUM60385.1 - 0.012 13.7 0.2 0.61 8.1 0.0 2.6 2 1 1 3 3 3 0 Nucleoporin Nup120/160 DUF4050 PF13259.1 KUM60386.1 - 0.99 9.3 5.9 2.6 7.9 4.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4050) EB1 PF03271.12 KUM60387.1 - 3.1e-16 59.1 0.5 5.5e-16 58.3 0.3 1.4 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 KUM60387.1 - 1.8e-06 27.9 1.7 3.2e-06 27.1 1.2 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Herpes_UL6 PF01763.11 KUM60387.1 - 0.054 11.6 0.0 0.081 11.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Adeno_E3_CR2 PF02439.10 KUM60388.1 - 0.0014 18.1 0.2 0.0024 17.4 0.1 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Rifin_STEVOR PF02009.11 KUM60388.1 - 0.14 11.7 0.0 0.41 10.2 0.0 1.6 1 1 0 1 1 1 0 Rifin/stevor family Syndecan PF01034.15 KUM60388.1 - 0.4 10.3 1.0 0.72 9.5 0.7 1.4 1 0 0 1 1 1 0 Syndecan domain Cation_ATPase_N PF00690.21 KUM60389.1 - 1.6e-09 37.0 0.2 4.6e-08 32.4 0.0 2.3 2 0 0 2 2 2 2 Cation transporter/ATPase, N-terminus E1-E2_ATPase PF00122.15 KUM60390.1 - 3.9e-49 166.7 0.1 3.9e-49 166.7 0.1 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KUM60390.1 - 1.9e-45 154.6 9.3 1.9e-45 154.6 6.5 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KUM60390.1 - 1.2e-27 97.7 0.0 3.7e-27 96.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KUM60390.1 - 2.2e-16 59.5 0.0 5.2e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KUM60390.1 - 7.2e-16 58.9 0.0 1.3e-15 58.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KUM60390.1 - 7.3e-06 25.7 0.1 0.00092 18.8 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 KUM60390.1 - 0.017 15.0 0.1 0.017 15.0 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3325) P16-Arc PF04699.9 KUM60391.1 - 7.9e-59 198.0 0.0 9.2e-59 197.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) PAS_4 PF08448.5 KUM60391.1 - 0.073 13.1 0.1 0.16 12.0 0.0 1.6 2 0 0 2 2 2 0 PAS fold Methyltransf_11 PF08241.7 KUM60392.1 - 2.2e-09 37.6 0.0 5.2e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM60392.1 - 7.2e-07 29.0 0.0 1.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM60392.1 - 5.1e-06 26.8 0.0 1e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM60392.1 - 0.00069 19.2 0.0 0.0023 17.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Dynactin_p62 PF05502.8 KUM60393.1 - 3.8e-189 629.4 0.0 5.2e-189 629.0 0.0 1.2 1 0 0 1 1 1 1 Dynactin p62 family Mu-like_Com PF10122.4 KUM60393.1 - 0.55 9.3 5.9 0.97 8.5 0.8 2.7 2 0 0 2 2 2 0 Mu-like prophage protein Com Trm112p PF03966.11 KUM60393.1 - 2.6 8.4 5.8 17 5.8 0.2 3.4 3 0 0 3 3 3 0 Trm112p-like protein Ribosomal_S7e PF01251.13 KUM60394.1 - 5.9e-84 280.2 0.1 7.4e-84 279.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7e Ras PF00071.17 KUM60395.1 - 2.8e-56 189.3 0.0 3.7e-56 188.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KUM60395.1 - 1e-20 74.4 0.0 1.6e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KUM60395.1 - 2.3e-14 53.0 0.0 3.7e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KUM60395.1 - 2.7e-06 26.7 0.0 3.1e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KUM60395.1 - 4.4e-06 26.2 0.0 1e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KUM60395.1 - 0.00017 21.5 0.0 0.00034 20.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KUM60395.1 - 0.0035 17.3 0.0 0.0083 16.1 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KUM60395.1 - 0.084 13.0 0.0 0.24 11.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain 6PGD PF00393.14 KUM60397.1 - 6e-57 193.0 0.0 8.5e-57 192.5 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KUM60397.1 - 5.4e-34 117.3 0.0 2.7e-33 115.1 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 KUM60397.1 - 1.5e-05 24.7 0.1 2.9e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 KUM60397.1 - 1.8e-05 24.4 0.0 3.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KUM60397.1 - 0.00047 19.3 0.0 0.0008 18.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KUM60397.1 - 0.00098 18.5 0.0 0.0032 16.8 0.0 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.16 KUM60397.1 - 0.0089 15.6 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.12 KUM60397.1 - 0.0094 16.3 0.0 0.027 14.8 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.22 KUM60397.1 - 0.018 15.4 0.0 0.042 14.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_11 PF14833.1 KUM60397.1 - 0.061 13.3 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase TehB PF03848.9 KUM60397.1 - 0.21 10.7 0.1 0.48 9.5 0.0 1.6 2 0 0 2 2 2 0 Tellurite resistance protein TehB AP_endonuc_2 PF01261.19 KUM60399.1 - 5.4e-29 101.0 0.0 6.6e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel adh_short PF00106.20 KUM60400.1 - 5.5e-10 39.4 0.0 8e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KUM60400.1 - 1.2e-05 24.8 0.0 1.6e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KUM60400.1 - 0.00012 21.9 0.0 0.00016 21.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.12 KUM60400.1 - 0.00061 18.7 0.0 0.0009 18.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KUM60400.1 - 0.00071 19.6 0.1 0.0017 18.4 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KUM60400.1 - 0.0031 16.8 0.0 0.0059 15.8 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family 2-Hacid_dh_C PF02826.14 KUM60400.1 - 0.0034 16.5 0.0 0.0079 15.3 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3173 PF11372.3 KUM60400.1 - 0.032 13.8 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3173) Beta_propel PF09826.4 KUM60400.1 - 0.033 12.5 0.0 0.042 12.1 0.0 1.1 1 0 0 1 1 1 0 Beta propeller domain F420_oxidored PF03807.12 KUM60400.1 - 0.088 13.2 0.0 0.3 11.5 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 KUM60401.1 - 2.9e-09 36.7 0.3 1.3e-08 34.5 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KUM60401.1 - 1.4e-08 33.8 0.4 2.6e-08 32.9 0.2 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KUM60401.1 - 6.6e-08 32.7 0.1 1.1e-07 32.0 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KUM60401.1 - 9.1e-06 25.0 0.3 1.5e-05 24.4 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KUM60401.1 - 1.8e-05 24.7 0.1 3.5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KUM60401.1 - 0.00061 18.7 0.6 0.011 14.6 0.2 2.8 2 1 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 KUM60401.1 - 0.0011 17.8 0.1 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KUM60401.1 - 0.0029 16.5 0.1 0.0045 15.9 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.13 KUM60401.1 - 0.0054 16.7 0.3 0.011 15.7 0.2 1.5 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.5 KUM60401.1 - 0.011 15.3 0.2 0.019 14.6 0.2 1.4 1 0 0 1 1 1 0 KR domain PMI_typeI PF01238.16 KUM60403.1 - 1.8e-49 168.7 0.0 2.4e-26 92.5 0.0 2.0 1 1 0 2 2 2 2 Phosphomannose isomerase type I Cupin_2 PF07883.6 KUM60403.1 - 0.03 13.8 0.1 6.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Cupin domain Caleosin PF05042.8 KUM60405.1 - 1.1e-51 174.8 0.0 1.4e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_1 PF00036.27 KUM60405.1 - 3.9e-05 22.6 4.0 0.00034 19.6 0.0 2.7 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 KUM60405.1 - 0.00045 19.8 4.5 0.00076 19.1 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 KUM60405.1 - 0.0011 19.0 0.1 0.0039 17.2 0.1 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 KUM60405.1 - 0.0018 17.8 0.2 0.037 13.6 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 KUM60405.1 - 0.022 14.0 0.2 0.022 14.0 0.1 2.7 3 0 0 3 3 3 0 EF hand PaaX_C PF08223.6 KUM60407.1 - 0.0056 16.3 0.0 0.037 13.7 0.1 2.2 2 0 0 2 2 2 1 PaaX-like protein C-terminal domain Nif11 PF07862.6 KUM60407.1 - 0.074 13.0 0.2 1.8 8.5 0.1 2.6 2 0 0 2 2 2 0 Nitrogen fixation protein of unknown function AAA PF00004.24 KUM60408.1 - 5.9e-16 58.8 0.0 2.4e-15 56.9 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KUM60408.1 - 1.3e-05 25.3 0.0 4.7e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KUM60408.1 - 0.00015 21.8 0.0 0.00068 19.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KUM60408.1 - 0.00016 22.4 0.0 0.00092 20.0 0.0 2.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KUM60408.1 - 0.0013 18.3 0.2 0.0035 17.0 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 KUM60408.1 - 0.0019 17.9 0.0 0.0057 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KUM60408.1 - 0.021 14.7 0.0 0.082 12.7 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KUM60408.1 - 0.034 13.7 0.0 0.16 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KUM60408.1 - 0.041 13.4 0.5 0.86 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KUM60408.1 - 0.087 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KUM60408.1 - 0.14 11.2 0.1 0.27 10.3 0.1 1.4 1 0 0 1 1 1 0 KaiC PhoH PF02562.11 KUM60408.1 - 0.15 11.2 0.1 0.37 9.9 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.16 KUM60408.1 - 0.19 10.8 0.0 0.37 9.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MFS_1 PF07690.11 KUM60411.1 - 5.7e-39 133.8 42.8 5.7e-39 133.8 29.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM60411.1 - 1e-09 37.5 9.3 1e-09 37.5 6.5 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter Fungal_trans PF04082.13 KUM60412.1 - 6.4e-11 41.6 0.0 2.9e-10 39.4 0.0 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM60412.1 - 1.7e-08 34.1 6.4 3.6e-08 33.1 4.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.23 KUM60413.1 - 1.3e-83 281.5 0.0 1.6e-83 281.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KUM60413.1 - 5.4e-08 32.6 0.1 1.6e-07 31.1 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KUM60413.1 - 0.0074 15.5 0.5 0.012 14.8 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 KUM60413.1 - 0.22 10.0 0.0 6.9 5.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) MFS_1 PF07690.11 KUM60414.1 - 2.3e-34 118.6 34.2 2.9e-34 118.3 23.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 KUM60414.1 - 0.012 16.0 0.0 0.028 14.8 0.0 1.6 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Amidase PF01425.16 KUM60415.1 - 2.7e-52 178.1 0.0 2.7e-48 164.9 0.0 2.2 1 1 1 2 2 2 2 Amidase PRP21_like_P PF12230.3 KUM60415.1 - 0.089 12.2 0.2 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein COesterase PF00135.23 KUM60416.1 - 3.3e-106 356.1 0.0 4.7e-106 355.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KUM60416.1 - 1.1e-08 34.9 0.4 4e-08 33.1 0.1 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KUM60416.1 - 0.0094 15.7 0.5 0.087 12.5 0.0 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Glyco_hydro_28 PF00295.12 KUM60419.1 - 4.7e-30 104.6 0.5 6.5e-30 104.2 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.2 KUM60419.1 - 3.7e-06 27.2 8.9 0.0001 22.4 5.3 2.7 1 1 1 2 2 2 1 Pectate lyase superfamily protein NST1 PF13945.1 KUM60420.1 - 0.086 12.9 2.1 0.092 12.8 1.5 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF3441 PF11923.3 KUM60421.1 - 2.8e-38 129.9 0.1 2.8e-38 129.9 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) FbpA PF05833.6 KUM60421.1 - 7.1e-35 120.4 12.4 7.1e-35 120.4 8.6 2.8 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 KUM60421.1 - 1.5e-15 56.8 0.0 3.3e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Glyco_transf_28 PF03033.15 KUM60422.1 - 5.8e-22 77.9 0.2 4.3e-21 75.1 0.0 2.5 2 1 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KUM60422.1 - 2.6e-05 22.9 0.0 4e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KUM60422.1 - 0.0066 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DUF2985 PF11204.3 KUM60423.1 - 1.2e-33 114.6 4.7 1.2e-33 114.6 3.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) Fungal_trans_2 PF11951.3 KUM60424.1 - 6.5e-56 189.5 3.1 8.3e-56 189.2 2.2 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Clat_adaptor_s PF01217.15 KUM60425.1 - 7.6e-11 41.9 0.0 2.2e-10 40.3 0.0 1.6 2 0 0 2 2 2 1 Clathrin adaptor complex small chain DUF948 PF06103.6 KUM60426.1 - 0.092 12.6 0.8 0.24 11.2 0.6 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) CALCOCO1 PF07888.6 KUM60426.1 - 0.22 9.7 25.2 0.019 13.2 12.0 2.1 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF342 PF03961.8 KUM60426.1 - 2.2 6.6 14.8 5.7 5.2 10.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Fib_alpha PF08702.5 KUM60426.1 - 8.5 6.4 16.5 0.45 10.6 4.4 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family IncA PF04156.9 KUM60426.1 - 9.8 5.7 33.3 0.18 11.3 16.9 2.3 2 0 0 2 2 2 0 IncA protein MIF4G_like_2 PF09090.6 KUM60426.1 - 9.9 5.2 12.6 6.9 5.8 5.7 2.4 1 1 1 2 2 2 0 MIF4G like Sulfatase PF00884.18 KUM60427.1 - 2.9e-43 148.2 3.1 2.1e-41 142.1 0.1 2.6 2 2 1 3 3 3 1 Sulfatase Phosphodiest PF01663.17 KUM60427.1 - 6.4e-09 35.5 0.0 6.6e-08 32.2 0.0 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 KUM60427.1 - 0.0022 18.2 0.1 0.0041 17.4 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF1501 PF07394.7 KUM60427.1 - 0.0058 15.5 0.0 0.0093 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) DUF229 PF02995.12 KUM60427.1 - 0.06 11.7 0.0 0.082 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Cellulase PF00150.13 KUM60428.1 - 3.3e-06 26.5 2.9 2.1e-05 23.9 1.3 2.4 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Pyr_redox_3 PF13738.1 KUM60429.1 - 1.1e-22 81.0 0.0 2.1e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KUM60429.1 - 8.1e-11 40.8 0.0 3.7e-09 35.3 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KUM60429.1 - 1.1e-10 41.3 0.2 8.4e-09 35.3 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KUM60429.1 - 8e-07 28.2 0.0 0.00074 18.5 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KUM60429.1 - 0.00036 20.3 0.4 0.08 12.7 0.0 3.5 3 1 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 KUM60429.1 - 0.00041 20.4 0.0 0.012 15.6 0.0 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 KUM60429.1 - 0.00043 19.4 0.0 0.16 11.0 0.0 3.1 3 0 0 3 3 3 1 Thi4 family 2-Hacid_dh_C PF02826.14 KUM60429.1 - 0.0041 16.2 0.0 0.0072 15.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 KUM60429.1 - 0.006 15.5 0.0 0.025 13.4 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Semialdhyde_dh PF01118.19 KUM60429.1 - 0.014 15.6 0.0 0.041 14.1 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KUM60429.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Dyp_perox PF04261.7 KUM60430.1 - 4.2e-93 311.5 0.0 4.8e-93 311.3 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family adh_short PF00106.20 KUM60431.1 - 3.1e-30 105.3 0.6 4.9e-30 104.6 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM60431.1 - 5.8e-25 88.4 0.0 7e-25 88.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM60431.1 - 1.2e-15 57.6 0.4 3.7e-15 56.0 0.3 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KUM60431.1 - 1.8e-07 30.3 0.2 4.4e-07 29.0 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KUM60431.1 - 2.1e-05 24.1 0.2 6.3e-05 22.5 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KUM60431.1 - 0.024 13.3 0.0 0.037 12.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DLH PF01738.13 KUM60432.1 - 0.0027 17.0 0.0 0.0029 16.9 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Sua5_yciO_yrdC PF01300.13 KUM60433.1 - 2.6e-55 186.4 0.0 4.2e-55 185.7 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 KUM60433.1 - 5.7e-27 94.2 0.0 1.1e-26 93.3 0.0 1.5 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding A_deaminase PF00962.17 KUM60434.1 - 9.9e-75 251.4 0.0 1.1e-74 251.2 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_4 PF13147.1 KUM60434.1 - 0.016 15.2 0.1 0.039 14.0 0.0 1.7 2 0 0 2 2 2 0 Amidohydrolase Ribosomal_L16 PF00252.13 KUM60435.1 - 3.4e-32 110.9 0.1 4.5e-32 110.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e MFS_1 PF07690.11 KUM60436.1 - 4.6e-18 65.0 19.2 6.4e-18 64.5 13.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2417 PF10329.4 KUM60436.1 - 0.025 13.9 1.3 7.6 5.8 1.2 2.5 2 0 0 2 2 2 0 Region of unknown function (DUF2417) PQ-loop PF04193.9 KUM60437.1 - 8.6e-36 121.3 10.3 6e-19 67.3 0.8 3.0 3 0 0 3 3 3 2 PQ loop repeat CYSTM PF12734.2 KUM60437.1 - 0.0019 18.2 0.0 0.0065 16.5 0.0 1.9 1 0 0 1 1 1 1 Cysteine-rich TM module stress tolerance Pro_dh PF01619.13 KUM60438.1 - 1.7e-43 148.8 0.1 2.2e-43 148.4 0.1 1.1 1 0 0 1 1 1 1 Proline dehydrogenase AP_endonuc_2 PF01261.19 KUM60438.1 - 0.004 16.4 0.0 0.0061 15.8 0.0 1.5 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Fungal_trans PF04082.13 KUM60440.1 - 5.2e-11 41.9 0.5 1.1e-10 40.8 0.4 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM60440.1 - 1.3e-07 31.3 12.5 1.3e-07 31.3 8.7 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PPR PF01535.15 KUM60441.1 - 0.095 12.7 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 PPR repeat RabGAP-TBC PF00566.13 KUM60442.1 - 1.3e-16 60.7 0.1 2.1e-16 60.0 0.1 1.4 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DinB_2 PF12867.2 KUM60442.1 - 0.099 12.9 0.8 0.24 11.7 0.4 1.8 1 1 1 2 2 2 0 DinB superfamily DUF2568 PF10823.3 KUM60444.1 - 0.094 12.9 0.4 0.31 11.3 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2568) PsbW PF07123.7 KUM60444.1 - 0.81 9.7 3.4 4.6 7.3 1.9 2.3 1 1 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) DAO PF01266.19 KUM60445.1 - 3.1e-40 138.1 0.0 3.6e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KUM60445.1 - 2.4e-05 24.2 0.0 6.1e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KUM60445.1 - 0.017 15.1 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 KUM60445.1 - 0.029 14.2 0.0 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 ThiF family Pyr_redox_2 PF07992.9 KUM60445.1 - 0.034 14.0 0.2 0.098 12.5 0.1 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KUM60445.1 - 0.039 14.3 0.0 0.17 12.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KUM60445.1 - 0.044 12.8 0.0 0.11 11.5 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain Aldedh PF00171.17 KUM60446.1 - 1.7e-94 316.7 0.0 2.2e-94 316.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KUM60446.1 - 0.069 11.8 0.1 0.65 8.6 0.0 2.2 2 1 0 2 2 2 0 Acyl-CoA reductase (LuxC) DUF1308 PF07000.6 KUM60446.1 - 0.073 11.7 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) Sugar_tr PF00083.19 KUM60447.1 - 2.1e-97 326.5 20.1 2.6e-97 326.2 13.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM60447.1 - 1.1e-23 83.5 37.1 6e-13 48.2 9.8 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Trp_oprn_chp PF09534.5 KUM60447.1 - 2 7.9 6.7 0.72 9.4 0.5 2.9 3 1 1 4 4 4 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Cpn60_TCP1 PF00118.19 KUM60448.1 - 7.6e-141 470.0 1.6 8.7e-141 469.8 1.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HSDR_N_2 PF13588.1 KUM60448.1 - 0.095 12.5 0.1 0.38 10.5 0.0 2.0 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Peptidase_C14 PF00656.17 KUM60449.1 - 5.7e-74 248.9 0.0 8.4e-74 248.3 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 KUM60449.1 - 0.056 13.2 0.5 0.23 11.2 0.0 2.3 2 1 0 2 2 2 0 Raptor N-terminal CASPase like domain MFS_1 PF07690.11 KUM60450.1 - 3.6e-20 71.9 37.6 3.6e-20 71.9 26.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1129 PF06570.6 KUM60450.1 - 0.14 11.4 1.2 0.32 10.2 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) zf-H2C2 PF09337.5 KUM60452.1 - 7e-22 76.5 4.2 1.2e-21 75.7 2.9 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 KUM60452.1 - 1.5e-05 24.9 0.0 2.9e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KUM60452.1 - 0.0031 17.4 0.0 0.006 16.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KUM60452.1 - 0.032 14.4 0.0 0.068 13.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KUM60452.1 - 0.074 12.9 0.0 0.21 11.4 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KUM60452.1 - 0.077 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein PAT1 PF09770.4 KUM60452.1 - 3.4 5.7 12.1 4.2 5.5 8.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 eRF1_1 PF03463.10 KUM60453.1 - 6.5e-44 148.7 0.0 1e-43 148.0 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 KUM60453.1 - 1.7e-20 73.3 0.0 3.1e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 KUM60453.1 - 4.8e-20 72.2 0.0 7.5e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 Aldo_ket_red PF00248.16 KUM60454.1 - 6.3e-44 149.8 0.1 8.1e-44 149.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.20 KUM60455.1 - 1.5e-57 194.6 0.0 2.2e-57 194.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM60455.1 - 2e-20 72.9 0.0 3.2e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM60455.1 - 1.6e-05 23.9 0.0 3.8e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KUM60455.1 - 6.8e-05 22.7 0.1 0.0042 16.8 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 KUM60455.1 - 0.00019 20.5 0.1 0.00065 18.8 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KUM60455.1 - 0.017 14.4 0.0 0.043 13.1 0.0 1.6 1 0 0 1 1 1 0 RIO1 family vATP-synt_E PF01991.13 KUM60456.1 - 0.08 12.2 0.5 0.14 11.4 0.4 1.3 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Hemagglutinin PF00509.13 KUM60456.1 - 0.12 10.4 0.4 0.18 9.9 0.3 1.1 1 0 0 1 1 1 0 Haemagglutinin FXR1P_C PF12235.3 KUM60456.1 - 5.6 7.0 8.5 0.22 11.6 1.5 2.0 2 1 1 3 3 3 0 Fragile X-related 1 protein C terminal PTS_2-RNA PF01885.11 KUM60457.1 - 2.7e-73 245.2 0.0 3.3e-73 244.9 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family CPSF100_C PF13299.1 KUM60457.1 - 0.11 12.6 0.2 0.19 11.9 0.2 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal AreA_N PF07573.6 KUM60457.1 - 0.26 11.8 7.0 2.4 8.7 0.6 2.5 1 1 1 2 2 2 0 Nitrogen regulatory protein AreA N terminus Dioxygenase_C PF00775.16 KUM60458.1 - 2.4e-51 173.5 0.0 3.2e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KUM60458.1 - 1.7e-11 43.9 0.1 2.7e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KUM60458.1 - 1.3e-05 25.1 0.0 5.8e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Cna_B PF05738.8 KUM60458.1 - 0.0082 15.8 0.0 0.032 14.0 0.0 2.0 2 0 0 2 2 2 1 Cna protein B-type domain DUF4480 PF13715.1 KUM60458.1 - 0.037 14.0 0.0 0.11 12.6 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4480) Abhydrolase_6 PF12697.2 KUM60459.1 - 1.9e-34 119.5 0.0 2.5e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM60459.1 - 3.8e-21 75.6 0.0 2.2e-15 56.8 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KUM60459.1 - 1.4e-18 67.0 0.5 3.4e-18 65.8 0.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KUM60459.1 - 1.4e-06 26.9 0.0 2.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Ndr family BAAT_C PF08840.6 KUM60459.1 - 0.00011 21.9 0.0 0.00028 20.6 0.0 1.6 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.15 KUM60459.1 - 0.00012 21.6 0.1 0.00021 20.7 0.1 1.4 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 KUM60459.1 - 0.00019 20.9 0.0 0.26 10.6 0.0 2.7 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KUM60459.1 - 0.0013 17.9 0.0 0.59 9.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.13 KUM60459.1 - 0.0028 16.9 0.0 2.1 7.5 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family PGAP1 PF07819.8 KUM60459.1 - 0.0032 17.0 0.9 0.013 15.0 0.2 2.1 2 0 0 2 2 2 1 PGAP1-like protein Ser_hydrolase PF06821.8 KUM60459.1 - 0.029 13.9 0.1 0.16 11.5 0.0 1.9 1 1 1 2 2 2 0 Serine hydrolase DUF676 PF05057.9 KUM60459.1 - 0.031 13.5 0.2 0.13 11.5 0.1 2.0 1 1 1 2 2 2 0 Putative serine esterase (DUF676) Thioesterase PF00975.15 KUM60459.1 - 0.033 14.4 0.0 0.038 14.1 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF915 PF06028.6 KUM60459.1 - 0.038 13.0 0.0 0.3 10.1 0.0 2.2 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) UPF0227 PF05728.7 KUM60459.1 - 0.096 12.4 0.1 0.18 11.5 0.1 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) PAF-AH_p_II PF03403.8 KUM60459.1 - 0.13 10.4 0.2 3.5 5.8 0.0 2.2 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II LCAT PF02450.10 KUM60459.1 - 0.14 11.1 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase NARP1 PF12569.3 KUM60460.1 - 0.077 11.7 5.8 0.99 8.0 5.8 1.4 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 CFIA_Pcf11 PF11526.3 KUM60460.1 - 0.25 11.5 2.4 6.7 6.9 0.0 2.5 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 Agouti PF05039.7 KUM60460.1 - 0.42 10.9 5.1 1.2 9.5 3.5 1.8 1 0 0 1 1 1 0 Agouti protein OmpH PF03938.9 KUM60460.1 - 6.8 6.6 10.5 6.4 6.6 6.2 1.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) F-box-like PF12937.2 KUM60461.1 - 2.4e-11 43.1 0.0 9.7e-11 41.2 0.0 2.2 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 KUM60461.1 - 2.4e-10 39.3 6.3 0.8 9.9 0.0 8.1 10 0 0 10 10 10 3 Leucine Rich repeat F-box PF00646.28 KUM60461.1 - 1.4e-07 31.0 0.0 1.2e-06 28.0 0.0 2.8 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.2 KUM60461.1 - 1.8e-05 24.2 4.0 0.027 14.1 0.0 4.5 4 1 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KUM60461.1 - 0.017 15.0 12.4 4.2 7.7 0.2 6.7 5 3 0 5 5 5 0 Leucine Rich Repeat PRANC PF09372.5 KUM60461.1 - 0.13 12.2 0.1 0.63 10.0 0.0 2.1 2 0 0 2 2 2 0 PRANC domain Recep_L_domain PF01030.19 KUM60461.1 - 0.34 10.9 1.5 7.5 6.5 0.1 3.3 2 2 2 4 4 4 0 Receptor L domain DUF2361 PF10153.4 KUM60463.1 - 9.5e-37 125.6 8.6 9.5e-37 125.6 6.0 2.8 3 0 0 3 3 3 1 Uncharacterised conserved protein (DUF2361) Zip PF02535.17 KUM60463.1 - 9.3 5.1 5.4 15 4.4 3.8 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter FUSC PF04632.7 KUM60464.1 - 0.44 8.9 0.4 0.62 8.4 0.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family zf-C3HC4_2 PF13923.1 KUM60464.1 - 1.2 9.2 10.7 0.15 12.1 2.2 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) AOX PF01786.12 KUM60465.1 - 5.8e-83 277.3 0.1 6.9e-83 277.1 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase BCS1_N PF08740.6 KUM60467.1 - 2.7e-52 177.1 1.2 5.1e-52 176.2 0.8 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KUM60467.1 - 6e-19 68.5 0.0 5e-08 33.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KUM60467.1 - 0.00055 20.7 2.6 0.00092 20.0 0.0 2.6 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.1 KUM60467.1 - 0.0016 17.8 0.0 0.023 14.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 KUM60467.1 - 0.016 14.9 0.0 0.051 13.3 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 KUM60467.1 - 0.022 14.7 0.1 0.053 13.4 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain KaiC PF06745.8 KUM60467.1 - 0.032 13.3 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 KaiC DUF815 PF05673.8 KUM60467.1 - 0.04 12.8 0.0 0.15 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 KUM60467.1 - 0.14 12.5 1.5 0.29 11.4 0.0 2.3 3 0 0 3 3 3 0 AAA domain UBN2_3 PF14244.1 KUM60468.1 - 4.4e-06 26.3 0.9 1.3e-05 24.7 0.3 2.0 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.1 KUM60468.1 - 0.029 14.0 1.7 0.059 13.0 1.1 1.5 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.12 KUM60468.1 - 2.4 8.2 5.2 2.1 8.4 1.4 2.5 3 0 0 3 3 3 0 Retrotransposon gag protein MFS_1 PF07690.11 KUM60471.1 - 8.8e-48 162.8 62.4 9.7e-47 159.3 43.2 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM60471.1 - 2e-16 59.3 18.1 2e-16 59.3 12.5 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KUM60471.1 - 9.3e-12 44.2 15.6 9.3e-12 44.2 10.8 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter PsbH PF00737.15 KUM60471.1 - 3.3 7.3 10.7 0.78 9.3 0.5 3.9 3 0 0 3 3 3 0 Photosystem II 10 kDa phosphoprotein XH PF03469.9 KUM60472.1 - 0.13 11.9 0.0 0.36 10.5 0.0 1.7 2 0 0 2 2 2 0 XH domain DUF3533 PF12051.3 KUM60473.1 - 1.8e-93 313.3 15.4 2.3e-93 312.9 10.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) CRF-BP PF05428.6 KUM60473.1 - 0.022 13.6 0.0 0.039 12.8 0.0 1.3 1 0 0 1 1 1 0 Corticotropin-releasing factor binding protein (CRF-BP) adh_short PF00106.20 KUM60474.1 - 1.7e-29 102.8 1.2 2.2e-29 102.5 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM60474.1 - 7.7e-22 78.2 0.2 9.9e-22 77.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM60474.1 - 1.4e-11 44.3 0.2 2.1e-11 43.8 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KUM60474.1 - 4.9e-09 36.4 0.5 9.6e-09 35.4 0.4 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KUM60474.1 - 7.7e-07 28.7 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 KUM60474.1 - 4.5e-05 22.7 0.0 6.4e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.8 KUM60474.1 - 0.00017 20.9 0.3 0.00025 20.3 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 KUM60474.1 - 0.00018 20.4 0.1 0.00025 20.0 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain F420_oxidored PF03807.12 KUM60474.1 - 0.00022 21.5 0.2 0.00056 20.2 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Eno-Rase_NADH_b PF12242.3 KUM60474.1 - 0.00067 19.3 0.5 0.002 17.8 0.4 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_zinc_N PF00107.21 KUM60474.1 - 0.07 12.6 2.5 0.16 11.4 1.5 1.8 2 1 0 2 2 2 0 Zinc-binding dehydrogenase 3HCDH_N PF02737.13 KUM60474.1 - 0.075 12.6 0.3 0.14 11.8 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RibD_C PF01872.12 KUM60475.1 - 1.3e-33 116.2 0.0 1.5e-33 116.1 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain MFS_1 PF07690.11 KUM60476.1 - 3.8e-23 81.7 22.4 1.7e-22 79.6 15.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KUM60476.1 - 6e-05 22.7 2.2 0.0003 20.5 1.3 2.5 2 0 0 2 2 2 1 MFS_1 like family Lectin_N PF03954.9 KUM60476.1 - 0.049 13.0 0.0 0.096 12.0 0.0 1.5 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF308 PF03729.8 KUM60476.1 - 0.063 13.2 6.4 0.27 11.2 4.4 2.1 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) Glyco_hydro_43 PF04616.9 KUM60477.1 - 1.3e-35 122.9 0.0 1.7e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 KUM60477.1 - 0.084 12.2 2.3 0.1 11.9 0.1 2.0 2 1 0 2 2 2 0 Glycosyl hydrolases family 32 N-terminal domain MFS_1 PF07690.11 KUM60478.1 - 2.9e-32 111.7 37.0 2.9e-32 111.7 25.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily DSBA PF01323.15 KUM60479.1 - 4.4e-13 49.2 0.0 5.1e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Phosphodiest PF01663.17 KUM60480.1 - 1.7e-87 294.1 0.3 2.1e-87 293.8 0.2 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KUM60480.1 - 7.6e-05 22.0 0.1 0.081 12.1 0.0 2.3 2 0 0 2 2 2 2 Sulfatase PglZ PF08665.7 KUM60480.1 - 0.025 14.2 0.0 0.075 12.6 0.0 1.7 2 0 0 2 2 2 0 PglZ domain Pex14_N PF04695.8 KUM60480.1 - 0.059 13.4 0.4 17 5.4 1.2 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region WD40 PF00400.27 KUM60481.1 - 1.3e-83 272.2 22.1 3.9e-13 48.7 0.2 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat Pkinase PF00069.20 KUM60481.1 - 3.3e-44 150.9 0.0 4.8e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM60481.1 - 6.1e-24 84.4 0.0 8.7e-24 83.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase eIF2A PF08662.6 KUM60481.1 - 3.4e-07 30.1 0.8 0.0013 18.4 0.0 3.4 1 1 2 4 4 4 4 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 KUM60481.1 - 1.7e-06 27.5 1.8 29 4.4 0.0 6.6 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 KUM60481.1 - 8.3e-06 25.0 1.2 1.6 7.7 0.0 4.4 2 1 2 4 4 4 1 Protein of unknown function (DUF1258) Cytochrom_D1 PF02239.11 KUM60481.1 - 1.8e-05 23.2 0.3 0.055 11.7 0.0 2.7 1 1 0 2 2 2 2 Cytochrome D1 heme domain IKI3 PF04762.7 KUM60481.1 - 0.00014 19.8 0.1 0.24 9.1 0.0 3.2 2 1 0 3 3 3 2 IKI3 family EBP PF05241.7 KUM60481.1 - 0.00027 20.0 0.1 2.7 6.9 0.0 3.6 2 1 1 3 3 3 2 Emopamil binding protein Proteasome_A_N PF10584.4 KUM60481.1 - 0.0077 15.5 9.4 7.5 5.9 0.0 6.6 7 0 0 7 7 7 1 Proteasome subunit A N-terminal signature Kdo PF06293.9 KUM60481.1 - 0.014 14.4 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TruB_C PF09142.6 KUM60481.1 - 0.039 13.5 0.2 1.2e+02 2.4 0.0 4.8 6 0 0 6 6 5 0 tRNA Pseudouridine synthase II, C terminal APH PF01636.18 KUM60481.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family HLH PF00010.21 KUM60483.1 - 4e-14 52.0 0.5 1e-13 50.7 0.1 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain ig PF00047.20 KUM60483.1 - 0.056 13.5 1.1 0.25 11.4 0.1 2.4 2 0 0 2 2 2 0 Immunoglobulin domain DUF4587 PF15248.1 KUM60483.1 - 0.46 11.1 8.3 3.3 8.3 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4587) Ank_2 PF12796.2 KUM60484.1 - 4.3e-36 123.1 6.2 1.2e-09 38.3 0.1 6.4 3 2 3 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KUM60484.1 - 2.1e-28 98.1 9.8 1.4e-07 31.7 0.0 8.5 7 4 3 10 10 10 4 Ankyrin repeats (many copies) Ank PF00023.25 KUM60484.1 - 5.9e-28 95.2 4.5 3.9e-07 29.5 0.1 10.2 9 3 1 10 10 10 6 Ankyrin repeat Ank_3 PF13606.1 KUM60484.1 - 1.6e-26 89.6 9.2 0.0051 16.9 0.0 10.3 12 0 0 12 12 12 7 Ankyrin repeat Ank_5 PF13857.1 KUM60484.1 - 4.9e-23 80.6 8.1 2.4e-09 37.1 0.0 6.0 5 2 1 6 6 6 3 Ankyrin repeats (many copies) DUF1571 PF07608.6 KUM60484.1 - 0.1 11.6 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1571) FAD_binding_4 PF01565.18 KUM60485.1 - 1.7e-19 69.6 1.7 4.2e-19 68.3 1.1 1.7 1 1 0 1 1 1 1 FAD binding domain Fungal_trans_2 PF11951.3 KUM60486.1 - 1.6e-10 40.1 0.4 2e-09 36.5 0.0 2.0 1 1 0 2 2 2 2 Fungal specific transcription factor domain BTB PF00651.26 KUM60487.1 - 0.0006 19.7 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Fungal_trans PF04082.13 KUM60488.1 - 1.1e-15 57.1 0.1 2.1e-15 56.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM60489.1 - 1.3e-10 41.0 13.1 2.1e-10 40.3 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KUM60490.1 - 2e-30 105.5 0.1 9.7e-30 103.3 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Peptidase_M41 PF01434.13 KUM60491.1 - 6.8e-74 247.9 0.0 1e-73 247.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KUM60491.1 - 1.4e-42 145.0 0.0 3e-42 143.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 KUM60491.1 - 8.3e-13 48.4 0.8 1.5e-12 47.6 0.0 1.9 2 0 0 2 2 1 1 FtsH Extracellular AAA_5 PF07728.9 KUM60491.1 - 0.00036 20.2 0.0 0.0014 18.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KUM60491.1 - 0.0012 18.9 0.1 0.22 11.6 0.1 2.7 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 KUM60491.1 - 0.0025 18.6 0.7 0.014 16.2 0.0 2.6 3 1 0 3 3 2 1 AAA domain RuvB_N PF05496.7 KUM60491.1 - 0.0063 15.5 0.0 0.019 14.0 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KUM60491.1 - 0.0064 16.2 0.5 0.02 14.5 0.4 1.8 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 KUM60491.1 - 0.0072 15.0 0.1 0.015 14.0 0.1 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 KUM60491.1 - 0.013 15.4 0.4 0.22 11.5 0.1 2.7 2 1 0 3 3 3 0 AAA ATPase domain IstB_IS21 PF01695.12 KUM60491.1 - 0.013 14.8 0.0 0.041 13.2 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.9 KUM60491.1 - 0.034 14.0 0.0 0.12 12.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 KUM60491.1 - 0.04 13.3 0.6 0.17 11.2 0.2 2.1 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 KUM60491.1 - 0.068 13.4 0.2 0.81 10.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.1 KUM60491.1 - 0.078 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KUM60491.1 - 0.093 12.6 0.0 0.3 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF2201_N PF13203.1 KUM60491.1 - 0.14 11.3 10.9 0.12 11.5 6.4 1.6 2 0 0 2 2 2 0 Putative metallopeptidase domain HNH_2 PF13391.1 KUM60492.1 - 5.9e-11 41.9 0.0 1.7e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease DUF1295 PF06966.7 KUM60493.1 - 3.5e-37 127.9 7.6 4.4e-37 127.6 5.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Topoisom_bac PF01131.15 KUM60494.1 - 2.6e-90 303.1 0.0 3.3e-90 302.8 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 KUM60494.1 - 9.4e-19 67.2 0.0 2.2e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 Toprim domain DUF3340 PF11818.3 KUM60495.1 - 0.078 12.9 0.2 0.95 9.4 0.0 2.2 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) TFIIA PF03153.8 KUM60496.1 - 0.2 11.5 12.0 0.21 11.4 8.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Astro_capsid PF03115.9 KUM60496.1 - 0.62 8.2 3.7 0.57 8.3 2.6 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Nop14 PF04147.7 KUM60496.1 - 1 7.1 16.9 1 7.1 11.7 1.1 1 0 0 1 1 1 0 Nop14-like family zf-C2H2_4 PF13894.1 KUM60496.1 - 8.8 6.9 6.0 1.3 9.4 1.3 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger HAMP PF00672.20 KUM60500.1 - 2e-49 165.6 16.5 7.7e-10 38.8 0.4 6.8 6 0 0 6 6 6 6 HAMP domain HATPase_c PF02518.21 KUM60500.1 - 1.8e-31 108.0 0.2 6.8e-31 106.2 0.1 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KUM60500.1 - 1.3e-27 95.9 1.4 2.4e-25 88.7 0.2 3.6 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.20 KUM60500.1 - 4.3e-16 58.6 0.1 4.3e-16 58.6 0.1 4.6 6 0 0 6 6 5 1 His Kinase A (phospho-acceptor) domain DUF2365 PF10157.4 KUM60500.1 - 0.024 14.5 21.2 1.5 8.6 0.0 7.1 7 2 0 8 8 8 0 Uncharacterized conserved protein (DUF2365) AAA_13 PF13166.1 KUM60500.1 - 0.025 13.0 32.0 0.13 10.7 4.0 4.1 1 1 2 4 4 4 0 AAA domain NOD PF06816.8 KUM60500.1 - 0.034 13.2 0.1 1.1 8.4 0.0 2.8 2 0 0 2 2 2 0 NOTCH protein PilJ PF13675.1 KUM60500.1 - 0.038 14.2 10.2 9.2 6.6 0.1 6.4 4 2 2 6 6 6 0 Type IV pili methyl-accepting chemotaxis transducer N-term Pox_A_type_inc PF04508.7 KUM60500.1 - 0.38 10.6 2.9 1.1 9.2 0.1 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat IncA PF04156.9 KUM60500.1 - 0.55 9.8 14.1 0.98 8.9 3.6 4.1 4 0 0 4 4 4 0 IncA protein Scaffolding_pro PF11418.3 KUM60500.1 - 0.56 10.5 10.6 37 4.7 0.0 5.6 6 0 0 6 6 6 0 Phi29 scaffolding protein NAAA-beta PF15508.1 KUM60500.1 - 0.95 9.8 6.1 18 5.7 0.1 5.3 6 1 0 6 6 4 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DnaJ PF00226.26 KUM60501.1 - 3.3e-08 33.1 0.1 4.8e-08 32.6 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 KUM60501.1 - 3.2e-07 30.2 0.1 6.3e-07 29.2 0.1 1.6 1 1 0 1 1 1 1 Pam16 DUF3918 PF13056.1 KUM60501.1 - 0.073 12.4 1.0 0.073 12.4 0.7 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3918) Ribosomal_L24e PF01246.15 KUM60502.1 - 4.3e-25 87.3 3.3 1.1e-24 85.9 2.3 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e Diphthamide_syn PF01866.12 KUM60503.1 - 1.9e-51 175.1 0.0 5.6e-51 173.6 0.0 1.6 2 0 0 2 2 2 1 Putative diphthamide synthesis protein Fe-ADH PF00465.14 KUM60504.1 - 4.6e-75 252.5 0.7 5.3e-75 252.3 0.5 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KUM60504.1 - 1.1e-15 57.6 0.2 1.5e-15 57.1 0.1 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase FAD_binding_4 PF01565.18 KUM60505.1 - 2e-20 72.6 4.2 4.2e-20 71.6 2.9 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KUM60505.1 - 2.8e-07 30.3 0.0 7.2e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like WD40 PF00400.27 KUM60507.1 - 6e-05 22.7 2.1 0.5 10.3 0.0 4.8 4 1 0 4 4 4 1 WD domain, G-beta repeat YL1 PF05764.8 KUM60507.1 - 0.019 14.5 4.4 0.029 13.9 3.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein AAA_12 PF13087.1 KUM60508.1 - 2.7e-34 118.2 0.0 6.1e-34 117.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KUM60508.1 - 6.6e-27 94.6 0.1 6.6e-27 94.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KUM60508.1 - 6.7e-07 28.9 0.2 4.2e-05 23.2 0.1 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KUM60508.1 - 5.6e-05 22.7 0.9 0.0006 19.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 KUM60508.1 - 0.00058 19.4 0.0 0.012 15.1 0.0 2.6 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 KUM60508.1 - 0.0023 18.0 0.0 0.011 15.8 0.0 2.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Spectrin PF00435.16 KUM60508.1 - 0.012 15.9 5.1 0.041 14.1 3.2 2.2 2 0 0 2 2 2 0 Spectrin repeat ResIII PF04851.10 KUM60508.1 - 0.037 13.8 0.0 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit V_ATPase_I PF01496.14 KUM60508.1 - 0.18 9.6 5.6 0.37 8.5 3.9 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 KUM60508.1 - 0.39 9.7 9.3 0.74 8.8 6.4 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Glyco_hydro_7 PF00840.15 KUM60509.1 - 2.7e-212 704.8 20.9 3.1e-212 704.6 14.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 zf-C2H2_4 PF13894.1 KUM60511.1 - 2e-06 27.7 14.5 0.02 15.1 0.1 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KUM60511.1 - 0.027 14.8 0.1 0.027 14.8 0.1 3.6 3 1 0 3 3 3 0 Zinc finger, C2H2 type Syntaxin-18_N PF10496.4 KUM60513.1 - 0.064 13.0 0.1 0.093 12.5 0.1 1.2 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus ATPgrasp_Ter PF15632.1 KUM60514.1 - 0.097 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon MARVEL PF01284.18 KUM60516.1 - 4.7e-08 32.9 0.4 7e-08 32.4 0.3 1.2 1 0 0 1 1 1 1 Membrane-associating domain Choline_transpo PF04515.7 KUM60516.1 - 0.0075 15.0 0.2 0.01 14.6 0.1 1.1 1 0 0 1 1 1 1 Plasma-membrane choline transporter RAP1 PF07218.6 KUM60516.1 - 4.6 5.2 5.7 6.3 4.7 3.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Methyltransf_3 PF01596.12 KUM60518.1 - 1.1e-15 57.2 0.0 1.6e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 KUM60518.1 - 1.1e-12 48.6 0.0 2.2e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 KUM60518.1 - 0.003 16.9 0.0 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_26 PF13659.1 KUM60518.1 - 0.011 15.7 0.1 0.033 14.2 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KUM60518.1 - 0.012 16.2 0.0 0.018 15.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF2119 PF09892.4 KUM60518.1 - 0.077 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2119) GFO_IDH_MocA PF01408.17 KUM60519.1 - 2.1e-26 92.7 0.1 3.8e-26 91.9 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KUM60519.1 - 3.4e-12 46.1 0.0 5.7e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DapB_N PF01113.15 KUM60519.1 - 0.00059 19.7 0.1 0.00099 19.0 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_3 PF03447.11 KUM60519.1 - 0.0012 19.2 0.0 0.0024 18.2 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ABC_tran PF00005.22 KUM60520.1 - 9.9e-46 155.4 0.0 9.4e-22 77.7 0.0 2.7 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 KUM60520.1 - 1.4e-20 74.4 0.5 9.9e-05 22.4 0.0 4.2 3 1 0 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 KUM60520.1 - 1e-19 70.1 2.0 1e-19 70.1 1.4 2.2 3 0 0 3 3 1 1 ABC transporter SMC_N PF02463.14 KUM60520.1 - 1.9e-10 40.3 0.2 0.13 11.4 0.0 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KUM60520.1 - 2.1e-08 33.5 0.1 0.001 18.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KUM60520.1 - 3.5e-08 34.0 1.8 0.04 14.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KUM60520.1 - 7.7e-07 29.9 0.0 0.011 16.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KUM60520.1 - 5.2e-06 26.6 0.0 0.14 12.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 KUM60520.1 - 5.3e-06 25.7 0.6 0.0028 16.8 0.0 2.7 3 0 0 3 3 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 KUM60520.1 - 8.6e-06 26.0 0.0 0.11 12.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KUM60520.1 - 2.3e-05 24.4 0.0 0.18 11.7 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.1 KUM60520.1 - 2.9e-05 24.1 0.0 0.022 14.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KUM60520.1 - 4.1e-05 23.7 0.1 0.65 10.1 0.0 3.5 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 KUM60520.1 - 7.3e-05 23.2 0.0 0.23 11.9 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein RNA_helicase PF00910.17 KUM60520.1 - 9.4e-05 22.5 0.1 1.8 8.7 0.0 3.6 4 0 0 4 4 3 2 RNA helicase MMR_HSR1 PF01926.18 KUM60520.1 - 0.00011 22.1 0.1 0.14 12.1 0.0 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase NACHT PF05729.7 KUM60520.1 - 0.00015 21.4 0.1 0.67 9.5 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_5 PF07728.9 KUM60520.1 - 0.00032 20.4 0.1 1.2 8.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_15 PF13175.1 KUM60520.1 - 0.00035 19.7 0.1 0.12 11.3 0.0 3.3 5 0 0 5 5 4 1 AAA ATPase domain AAA_25 PF13481.1 KUM60520.1 - 0.0005 19.5 0.0 0.85 8.9 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 KUM60520.1 - 0.00076 19.3 0.1 0.17 11.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 KUM60520.1 - 0.0013 18.6 0.0 2.8 7.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 KUM60520.1 - 0.0013 17.6 0.0 1.2 7.9 0.0 3.1 2 1 0 2 2 2 1 NB-ARC domain AAA_10 PF12846.2 KUM60520.1 - 0.0017 17.8 1.0 0.68 9.3 0.2 3.1 3 0 0 3 3 3 1 AAA-like domain MobB PF03205.9 KUM60520.1 - 0.0022 17.6 0.1 0.055 13.1 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 KUM60520.1 - 0.0023 17.6 0.0 3.4 7.2 0.0 3.1 3 0 0 3 3 3 1 Archaeal ATPase SbcCD_C PF13558.1 KUM60520.1 - 0.0034 17.2 0.3 0.32 10.9 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.20 KUM60520.1 - 0.0037 16.7 0.0 0.048 13.1 0.0 2.5 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain DAP3 PF10236.4 KUM60520.1 - 0.026 13.4 0.9 6.4 5.6 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 DUF87 PF01935.12 KUM60520.1 - 0.071 12.9 0.7 16 5.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF87 NTPase_1 PF03266.10 KUM60520.1 - 0.076 12.7 0.2 7 6.3 0.1 2.5 2 0 0 2 2 2 0 NTPase Dynamin_N PF00350.18 KUM60520.1 - 0.3 10.8 2.6 40 3.9 0.0 3.6 3 1 1 4 4 4 0 Dynamin family DUF2813 PF11398.3 KUM60520.1 - 0.33 10.0 2.2 13 4.7 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) DUF3584 PF12128.3 KUM60520.1 - 4.6 4.4 8.8 0.21 8.8 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) AAA PF00004.24 KUM60521.1 - 2.6e-40 137.6 0.0 4.8e-40 136.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KUM60521.1 - 7.2e-07 29.4 0.2 0.00023 21.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KUM60521.1 - 1.4e-05 25.0 0.0 3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KUM60521.1 - 1.9e-05 23.7 0.0 3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 KUM60521.1 - 2.7e-05 23.9 0.0 7.8e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KUM60521.1 - 0.00028 20.9 0.1 0.0012 18.8 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KUM60521.1 - 0.00074 18.6 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KUM60521.1 - 0.0022 17.9 0.9 0.0045 16.9 0.0 2.0 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 KUM60521.1 - 0.0042 17.8 0.2 0.013 16.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KUM60521.1 - 0.0046 16.8 0.0 0.0083 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KUM60521.1 - 0.0068 16.1 0.3 0.016 14.9 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KUM60521.1 - 0.007 15.8 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 KUM60521.1 - 0.009 15.1 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin PhoH PF02562.11 KUM60521.1 - 0.011 15.0 0.6 0.21 10.7 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.1 KUM60521.1 - 0.012 15.5 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KUM60521.1 - 0.013 15.7 0.0 0.03 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KUM60521.1 - 0.014 14.9 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 KUM60521.1 - 0.019 13.6 0.0 0.043 12.5 0.0 1.5 1 0 0 1 1 1 0 TIP49 C-terminus NACHT PF05729.7 KUM60521.1 - 0.027 14.1 0.1 0.34 10.5 0.0 2.2 1 1 0 2 2 2 0 NACHT domain KaiC PF06745.8 KUM60521.1 - 0.032 13.3 0.2 0.42 9.6 0.0 2.2 1 1 1 2 2 2 0 KaiC NB-ARC PF00931.17 KUM60521.1 - 0.039 12.8 0.0 0.064 12.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 KUM60521.1 - 0.04 14.0 0.0 0.091 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 KUM60521.1 - 0.049 13.0 1.6 0.25 10.7 0.3 2.3 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 KUM60521.1 - 0.049 13.2 0.2 0.14 11.7 0.2 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KUM60521.1 - 0.054 12.6 0.1 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 KUM60521.1 - 0.14 11.0 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.21 KUM60521.1 - 0.14 11.5 0.1 0.81 9.1 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain WD40 PF00400.27 KUM60522.1 - 1.2e-22 78.8 18.7 6.3e-09 35.3 0.8 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KUM60522.1 - 0.001 17.8 0.2 0.018 13.8 0.0 2.5 1 1 1 2 2 2 1 Nup133 N terminal like Cwf_Cwc_15 PF04889.7 KUM60522.1 - 0.043 13.5 5.5 0.088 12.5 3.8 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Senescence_reg PF04520.8 KUM60522.1 - 0.12 12.8 5.2 0.05 14.1 1.2 2.1 2 0 0 2 2 2 0 Senescence regulator PBP1_TM PF14812.1 KUM60522.1 - 0.33 11.2 5.3 1 9.7 3.7 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.7 KUM60522.1 - 1.5 7.9 6.1 2.3 7.3 4.2 1.2 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 KUM60522.1 - 1.8 8.0 6.7 3.9 6.9 4.6 1.5 1 0 0 1 1 1 0 Nucleoplasmin Cyclin_N PF00134.18 KUM60523.1 - 7.5e-06 25.5 0.0 1.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 KUM60523.1 - 0.085 12.6 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Transcription factor TFIIB repeat UQ_con PF00179.21 KUM60524.1 - 1.7e-42 144.1 0.0 2.1e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 KUM60524.1 - 4.8e-05 22.8 0.0 9.8e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 KUM60524.1 - 0.0001 22.0 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KUM60524.1 - 0.024 14.5 0.2 0.037 13.9 0.1 1.4 1 1 0 1 1 1 0 RWD domain UEV PF05743.8 KUM60524.1 - 0.032 13.8 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain Glyco_hydro_3 PF00933.16 KUM60526.1 - 0.00011 21.2 0.0 0.00012 21.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Mg_trans_NIPA PF05653.9 KUM60527.1 - 1.2e-61 208.3 2.6 1.5e-57 194.8 1.6 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 KUM60527.1 - 3.1e-05 24.1 0.4 3.1e-05 24.1 0.3 3.0 3 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KUM60527.1 - 0.00012 22.0 1.0 0.00012 22.0 0.7 3.4 3 1 0 3 3 3 1 EamA-like transporter family DUF1211 PF06736.6 KUM60527.1 - 2.1 8.5 5.7 17 5.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1211) OPT PF03169.10 KUM60528.1 - 2.4e-184 614.3 56.9 2.7e-184 614.1 39.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Glyco_hydro_3_C PF01915.17 KUM60529.1 - 3.7e-61 206.5 1.1 1.3e-60 204.7 0.0 2.0 1 1 1 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 KUM60529.1 - 1.2e-56 191.9 0.0 1.6e-56 191.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 KUM60529.1 - 1.6e-21 76.0 1.6 1.8e-21 75.8 0.1 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain Sugar-bind PF04198.8 KUM60529.1 - 0.03 13.2 0.0 0.052 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain DUF1034 PF06280.7 KUM60529.1 - 0.064 13.6 1.5 0.13 12.7 1.0 1.5 1 0 0 1 1 1 0 Fn3-like domain (DUF1034) NAD_binding_10 PF13460.1 KUM60529.1 - 0.19 11.7 2.0 0.39 10.7 0.2 2.2 2 1 1 3 3 3 0 NADH(P)-binding TcdB_N PF12918.2 KUM60530.1 - 0.051 13.6 0.9 0.12 12.4 0.7 1.6 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain FlaC_arch PF05377.6 KUM60530.1 - 0.081 12.8 0.8 0.22 11.4 0.5 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF3837 PF12939.2 KUM60530.1 - 0.11 12.5 0.3 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3837) Rootletin PF15035.1 KUM60530.1 - 1.1 9.1 8.2 4.9 7.1 5.7 2.0 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DivIC PF04977.10 KUM60530.1 - 1.2 8.7 4.2 4.1 6.9 2.9 1.9 1 0 0 1 1 1 0 Septum formation initiator LysR_substrate PF03466.15 KUM60531.1 - 0.11 11.6 0.0 0.38 9.8 0.0 1.8 2 0 0 2 2 2 0 LysR substrate binding domain Fungal_trans_2 PF11951.3 KUM60533.1 - 2.5e-05 23.0 0.1 3.6e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RVP_2 PF08284.6 KUM60534.1 - 0.066 13.1 0.0 0.086 12.7 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease Trypan_PARP PF05887.6 KUM60535.1 - 0.029 14.2 37.4 0.21 11.4 13.0 2.1 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) GRAM PF02893.15 KUM60536.1 - 5.1e-17 61.1 0.0 1.1e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 GRAM domain DNA_pol_phi PF04931.8 KUM60536.1 - 2.4 5.7 7.1 3.6 5.2 4.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sugar_tr PF00083.19 KUM60537.1 - 1e-65 222.0 21.2 1.2e-65 221.8 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM60537.1 - 1.3e-14 53.7 22.3 1.3e-14 53.7 15.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Inhibitor_I34 PF10466.4 KUM60538.1 - 0.032 14.3 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 Saccharopepsin inhibitor I34 UBN2_3 PF14244.1 KUM60538.1 - 0.084 12.4 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type FAD_binding_3 PF01494.14 KUM60539.1 - 7.5e-33 114.0 0.0 1.3e-31 109.9 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KUM60539.1 - 1.5e-09 37.2 0.1 0.00015 20.7 0.1 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KUM60539.1 - 3.8e-06 27.1 0.1 1.3e-05 25.3 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KUM60539.1 - 4.5e-06 25.8 0.0 0.013 14.4 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Amino_oxidase PF01593.19 KUM60539.1 - 1e-05 24.8 0.0 0.0014 17.7 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase SE PF08491.5 KUM60539.1 - 3e-05 22.9 0.0 0.00016 20.6 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase Trp_halogenase PF04820.9 KUM60539.1 - 3.3e-05 22.7 0.4 0.1 11.1 0.1 3.1 2 1 1 3 3 3 2 Tryptophan halogenase Pyr_redox_2 PF07992.9 KUM60539.1 - 3.4e-05 23.8 0.1 0.00011 22.1 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KUM60539.1 - 5e-05 22.3 1.6 0.00068 18.6 0.1 2.2 1 1 1 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KUM60539.1 - 7.4e-05 21.3 0.0 0.0079 14.7 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 KUM60539.1 - 0.00013 21.9 0.1 0.00033 20.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KUM60539.1 - 0.0023 18.2 0.5 3.8 7.9 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM60539.1 - 0.0098 15.6 0.2 0.32 10.7 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 KUM60539.1 - 0.041 12.9 0.0 0.076 12.0 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 KUM60539.1 - 0.081 11.7 0.1 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HPP PF04982.8 KUM60540.1 - 1.1e-34 118.8 6.0 1.1e-34 118.8 4.2 1.5 2 0 0 2 2 2 1 HPP family Na_H_Exchanger PF00999.16 KUM60542.1 - 1.4e-68 231.1 50.8 2.1e-68 230.6 35.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family ADH_N PF08240.7 KUM60543.1 - 1.3e-23 82.8 1.8 2.5e-23 81.9 1.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Aminotran_4 PF01063.14 KUM60543.1 - 1.3e-20 73.8 0.0 2.3e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class IV ADH_zinc_N PF00107.21 KUM60543.1 - 3.6e-09 36.2 0.0 9.9e-06 25.1 0.0 2.6 2 0 0 2 2 2 2 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KUM60543.1 - 0.0059 15.7 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain BNR_2 PF13088.1 KUM60543.1 - 0.032 13.5 0.0 0.054 12.7 0.0 1.3 1 0 0 1 1 1 0 BNR repeat-like domain ABC2_membrane PF01061.19 KUM60544.1 - 1.4e-80 269.4 50.8 3.7e-41 140.5 12.9 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KUM60544.1 - 2.3e-36 125.0 0.0 5.5e-18 65.5 0.0 3.2 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 KUM60544.1 - 1.9e-33 114.1 1.5 1.8e-27 94.9 0.0 2.7 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KUM60544.1 - 1.1e-17 63.9 0.0 3e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KUM60544.1 - 1.8e-10 40.5 0.1 0.00012 21.6 0.0 2.6 3 0 0 3 3 2 2 AAA domain ABC2_membrane_3 PF12698.2 KUM60544.1 - 7.8e-09 35.0 31.9 1.4e-05 24.3 4.9 3.4 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_33 PF13671.1 KUM60544.1 - 5.3e-05 23.1 0.1 0.043 13.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KUM60544.1 - 0.00014 21.5 0.6 0.46 10.2 0.1 3.0 2 0 0 2 2 2 2 Part of AAA domain AAA_16 PF13191.1 KUM60544.1 - 0.00017 21.6 0.9 0.017 15.1 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KUM60544.1 - 0.00027 21.7 0.0 0.13 13.0 0.0 3.3 4 0 0 4 4 2 1 AAA domain DUF258 PF03193.11 KUM60544.1 - 0.00032 19.9 0.0 0.0011 18.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 UPF0079 PF02367.12 KUM60544.1 - 0.0019 17.8 1.2 0.81 9.3 0.1 2.6 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 KUM60544.1 - 0.0022 18.3 0.0 0.089 13.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 KUM60544.1 - 0.0029 17.2 0.6 1.5 8.4 0.1 2.7 2 0 0 2 2 2 2 NACHT domain AAA_29 PF13555.1 KUM60544.1 - 0.0085 15.5 2.4 0.034 13.6 0.0 2.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KUM60544.1 - 0.01 15.9 2.2 0.31 11.1 0.0 3.4 2 1 0 2 2 2 0 AAA domain SMC_N PF02463.14 KUM60544.1 - 0.012 14.9 0.2 0.41 9.8 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KUM60544.1 - 0.018 15.3 0.0 2.2 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KUM60544.1 - 0.032 14.4 0.2 6.7 6.9 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.1 KUM60544.1 - 0.063 13.2 0.1 0.78 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 KUM60544.1 - 0.073 12.5 7.4 0.026 13.9 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 KUM60544.1 - 0.22 10.9 0.2 14 5.0 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain Methyltransf_23 PF13489.1 KUM60546.1 - 6.5e-13 48.7 0.0 1.1e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM60546.1 - 2.9e-12 46.9 0.0 1.3e-11 44.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM60546.1 - 6.3e-10 39.4 0.0 2.8e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM60546.1 - 1.3e-07 31.3 0.0 1.9e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM60546.1 - 2.8e-07 31.1 0.0 4.8e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KUM60546.1 - 0.021 13.9 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.6 KUM60546.1 - 0.037 12.7 0.0 0.049 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DREV PF05219.7 KUM60546.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Ribonuc_2-5A PF06479.7 KUM60547.1 - 3.3e-41 140.1 0.0 6.1e-41 139.2 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 KUM60547.1 - 3.8e-41 140.9 0.0 5.8e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM60547.1 - 1.3e-20 73.5 0.0 2.6e-20 72.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 KUM60547.1 - 0.00091 18.6 0.0 0.066 12.7 0.0 3.0 2 0 0 2 2 2 1 PQQ enzyme repeat PQQ_2 PF13360.1 KUM60547.1 - 0.01 15.3 0.0 0.26 10.6 0.0 2.3 2 0 0 2 2 2 0 PQQ-like domain Kdo PF06293.9 KUM60547.1 - 0.03 13.3 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KUM60547.1 - 0.041 13.2 0.0 0.083 12.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Cytokin_check_N PF10407.4 KUM60548.1 - 0.0027 17.2 0.0 0.0065 16.0 0.0 1.5 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus Fungal_trans_2 PF11951.3 KUM60551.1 - 1.7e-06 26.9 0.2 4.1e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3602 PF12223.3 KUM60554.1 - 4.2e-22 78.3 5.2 2.6e-18 66.1 0.8 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) ECH PF00378.15 KUM60555.1 - 1.3e-33 116.1 0.0 1.7e-33 115.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pam17 PF08566.5 KUM60556.1 - 6.4e-68 227.8 0.0 8.6e-68 227.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 MFS_1 PF07690.11 KUM60558.1 - 1e-27 96.8 31.2 1e-27 96.8 21.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Far-17a_AIG1 PF04750.9 KUM60559.1 - 8.4e-73 243.8 10.1 1.1e-72 243.3 7.0 1.2 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Claudin_2 PF13903.1 KUM60559.1 - 2.7 7.6 7.7 0.41 10.3 1.4 2.2 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Fungal_trans_2 PF11951.3 KUM60560.1 - 2.3e-50 171.3 1.1 3.7e-50 170.6 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM60560.1 - 1.4e-09 37.6 8.2 2.5e-09 36.8 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_76 PF03663.9 KUM60561.1 - 1.8e-135 452.0 22.2 2.3e-135 451.7 15.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Cloacin_immun PF03513.9 KUM60561.1 - 0.00049 20.0 0.1 0.0012 18.8 0.1 1.6 1 0 0 1 1 1 1 Cloacin immunity protein Cpn60_TCP1 PF00118.19 KUM60562.1 - 8.2e-133 443.5 8.8 9.8e-133 443.2 6.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pro_isomerase PF00160.16 KUM60563.1 - 4.2e-49 166.7 0.1 8.2e-49 165.7 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 KUM60563.1 - 7.4e-16 57.3 0.6 1.1e-05 25.1 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat PrpR_N PF06506.6 KUM60563.1 - 0.044 13.1 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 Propionate catabolism activator Rifin_STEVOR PF02009.11 KUM60564.1 - 0.026 14.1 0.0 0.035 13.7 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family LAP1C PF05609.7 KUM60564.1 - 0.052 12.2 0.6 0.07 11.7 0.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF3619 PF12279.3 KUM60564.1 - 0.079 13.0 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Synaptobrevin PF00957.16 KUM60564.1 - 0.11 12.0 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Synaptobrevin DUF4381 PF14316.1 KUM60564.1 - 0.2 11.7 1.2 0.37 10.8 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Tme5_EGF_like PF09064.5 KUM60564.1 - 0.36 10.4 2.5 0.82 9.3 1.7 1.5 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like Fungal_trans_2 PF11951.3 KUM60565.1 - 4.4e-14 51.8 1.1 9.1e-14 50.8 0.7 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 KUM60565.1 - 0.0031 16.4 1.3 0.0065 15.3 0.9 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM60565.1 - 0.0042 16.9 5.7 0.007 16.2 3.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F_bP_aldolase PF01116.15 KUM60566.1 - 1.7e-70 237.4 0.5 2e-70 237.1 0.4 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II adh_short PF00106.20 KUM60567.1 - 3.9e-25 88.6 0.2 1.6e-24 86.6 0.2 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM60567.1 - 4.2e-19 69.2 0.0 5e-19 69.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM60567.1 - 5.4e-09 35.9 0.2 1.2e-08 34.8 0.2 1.5 2 0 0 2 2 2 1 KR domain 3Beta_HSD PF01073.14 KUM60567.1 - 0.093 11.4 0.1 0.15 10.7 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KUM60568.1 - 9.4e-25 87.4 1.3 1.2e-24 87.1 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM60568.1 - 1.9e-23 83.4 0.0 2.5e-23 83.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM60568.1 - 4.5e-07 29.7 0.4 7e-07 29.0 0.3 1.4 1 1 0 1 1 1 1 KR domain MFS_1 PF07690.11 KUM60569.1 - 1.4e-41 142.4 43.5 1.4e-40 139.1 29.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KUM60569.1 - 2.2e-15 55.9 24.5 3.1e-15 55.4 16.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KUM60569.1 - 4.6e-13 48.5 9.7 4.6e-13 48.5 6.8 3.3 3 1 1 4 4 4 1 Sugar (and other) transporter Polyoma_lg_T_C PF06431.6 KUM60570.1 - 0.088 11.4 0.2 0.14 10.7 0.1 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus Na_H_Exchanger PF00999.16 KUM60571.1 - 4.1e-33 114.4 38.1 6.2e-26 90.8 18.8 3.0 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family PigN PF04987.9 KUM60572.1 - 4.7e-172 572.5 33.4 7e-172 572.0 23.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 KUM60572.1 - 2.4e-11 43.5 0.1 4e-09 36.2 0.1 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KUM60572.1 - 2.7e-10 39.9 0.5 5.6e-10 38.8 0.1 1.7 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 KUM60572.1 - 0.00067 19.1 0.1 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Fungal_trans PF04082.13 KUM60573.1 - 3.4e-33 114.6 0.0 1.8e-31 108.9 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM60573.1 - 0.027 14.3 4.3 0.046 13.6 3.0 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Macoilin PF09726.4 KUM60573.1 - 3.5 5.7 5.1 5.4 5.1 3.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Ferric_reduct PF01794.14 KUM60574.1 - 4e-18 65.7 14.9 4e-18 65.7 10.3 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KUM60574.1 - 8.6e-16 57.7 0.0 1.8e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KUM60574.1 - 3.6e-11 43.2 0.0 5.8e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF4405 PF14358.1 KUM60574.1 - 0.0057 16.7 9.5 0.11 12.6 1.6 3.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4405) PALP PF00291.20 KUM60575.1 - 1.3e-27 96.8 0.0 2.2e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.15 KUM60575.1 - 8.2e-09 35.8 0.0 2.7e-08 34.1 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain Cys_Met_Meta_PP PF01053.15 KUM60576.1 - 1.1e-140 468.3 0.0 1.3e-140 468.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.6 KUM60576.1 - 6.5e-05 21.3 0.0 0.00037 18.9 0.0 1.9 1 1 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.14 KUM60576.1 - 0.00069 18.4 0.0 0.0012 17.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KUM60576.1 - 0.00072 18.7 0.0 0.0019 17.3 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KUM60576.1 - 0.0015 17.6 0.0 0.0046 16.1 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase AAA PF00004.24 KUM60578.1 - 3e-37 127.7 0.0 6e-37 126.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KUM60578.1 - 8.7e-06 25.6 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KUM60578.1 - 1.2e-05 26.1 0.0 3.2e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KUM60578.1 - 2.5e-05 24.4 0.1 0.00067 19.8 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KUM60578.1 - 4.9e-05 23.3 0.3 0.0012 18.8 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 KUM60578.1 - 5.5e-05 22.3 0.0 9.5e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KUM60578.1 - 8.1e-05 22.3 0.2 0.00078 19.1 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KUM60578.1 - 9.3e-05 22.4 0.0 0.00021 21.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 KUM60578.1 - 0.00024 21.0 0.0 0.00047 20.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KUM60578.1 - 0.00035 20.0 0.2 0.032 13.6 0.2 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KUM60578.1 - 0.00046 19.6 0.0 0.0011 18.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 KUM60578.1 - 0.00067 18.8 0.1 0.0012 18.0 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KUM60578.1 - 0.00093 19.3 0.0 0.0028 17.7 0.0 1.9 1 1 0 1 1 1 1 RNA helicase Sigma54_activ_2 PF14532.1 KUM60578.1 - 0.0012 18.9 0.0 0.004 17.2 0.0 1.8 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.1 KUM60578.1 - 0.0025 18.1 0.2 0.01 16.1 0.0 2.1 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.1 KUM60578.1 - 0.0026 17.7 0.0 0.0058 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KUM60578.1 - 0.0037 16.9 0.0 0.0097 15.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.1 KUM60578.1 - 0.006 16.1 0.0 0.0097 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KUM60578.1 - 0.007 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 KUM60578.1 - 0.012 15.3 0.4 0.054 13.2 0.1 2.1 2 0 0 2 2 2 0 Part of AAA domain Sigma54_activat PF00158.21 KUM60578.1 - 0.029 13.8 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 KUM60578.1 - 0.033 14.4 0.0 0.1 12.9 0.0 1.9 2 1 0 2 2 1 0 ABC transporter Parvo_NS1 PF01057.12 KUM60578.1 - 0.037 12.8 0.0 0.058 12.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 CPT PF07931.7 KUM60578.1 - 0.041 13.5 0.1 0.099 12.2 0.0 1.7 2 0 0 2 2 1 0 Chloramphenicol phosphotransferase-like protein Arch_ATPase PF01637.13 KUM60578.1 - 0.055 13.1 0.0 0.2 11.3 0.0 1.8 1 1 1 2 2 2 0 Archaeal ATPase DUF815 PF05673.8 KUM60578.1 - 0.056 12.3 0.0 0.098 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.1 KUM60578.1 - 0.09 12.3 0.1 0.39 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain SKI PF01202.17 KUM60578.1 - 0.096 12.5 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 Shikimate kinase KaiC PF06745.8 KUM60578.1 - 0.1 11.7 0.0 0.49 9.4 0.0 2.0 1 1 1 2 2 2 0 KaiC UPF0079 PF02367.12 KUM60578.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Rad17 PF03215.10 KUM60578.1 - 0.13 10.9 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 KUM60578.1 - 0.15 10.9 0.0 0.48 9.2 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain Csm1 PF12539.3 KUM60579.1 - 6.2e-27 93.9 0.1 1.2e-26 92.9 0.1 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 Vps5 PF09325.5 KUM60579.1 - 0.014 14.6 6.6 0.037 13.2 4.6 1.8 1 1 0 1 1 1 0 Vps5 C terminal like USP8_interact PF08941.5 KUM60579.1 - 0.26 10.5 1.7 0.33 10.2 0.4 1.7 1 1 1 2 2 2 0 USP8 interacting Spc7 PF08317.6 KUM60579.1 - 0.3 9.6 9.6 0.64 8.6 6.6 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 KUM60579.1 - 0.47 10.0 14.5 5 6.6 7.6 2.6 1 1 1 2 2 2 0 IncA protein AAA_13 PF13166.1 KUM60579.1 - 1.5 7.1 13.7 0.015 13.8 3.8 1.7 2 0 0 2 2 2 0 AAA domain GAS PF13851.1 KUM60579.1 - 2.5 7.2 14.3 7.1 5.7 8.5 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding COG2 PF06148.6 KUM60579.1 - 3.2 7.6 9.9 2.9 7.7 4.5 2.5 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.7 KUM60579.1 - 3.2 7.5 8.2 3.4 7.4 4.4 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 KUM60579.1 - 4.8 6.2 6.4 3.1 6.9 2.0 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DIT1_PvcA PF05141.7 KUM60581.1 - 8.7e-75 251.5 0.0 1.1e-74 251.2 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein DUF4066 PF13278.1 KUM60582.1 - 2.3e-18 65.9 0.0 8.3e-18 64.2 0.0 1.9 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KUM60582.1 - 5.3e-07 29.2 0.0 7.7e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family MTP18 PF10558.4 KUM60583.1 - 9.2e-68 226.8 0.3 1.3e-67 226.3 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) DUF2964 PF11177.3 KUM60583.1 - 0.067 13.1 0.2 0.17 11.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) ACPS PF01648.15 KUM60584.1 - 1.4e-16 60.2 0.0 1.9e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily DUF2611 PF11022.3 KUM60585.1 - 2.6e-28 97.8 0.1 3e-28 97.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) FKBP_C PF00254.23 KUM60586.1 - 1.9e-22 79.0 0.0 2.6e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PHP PF02811.14 KUM60587.1 - 3.6e-13 49.6 0.0 6.8e-13 48.7 0.0 1.4 1 1 0 1 1 1 1 PHP domain BRE PF06113.7 KUM60588.1 - 0.074 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) gpUL132 PF11359.3 KUM60588.1 - 4.7 6.4 7.1 0.5 9.6 0.5 2.2 2 0 0 2 2 2 0 Glycoprotein UL132 COesterase PF00135.23 KUM60589.1 - 1.5e-65 221.9 0.0 1.5e-34 119.6 0.0 2.7 2 1 0 2 2 2 2 Carboxylesterase family DIT1_PvcA PF05141.7 KUM60590.1 - 5.6e-58 196.4 0.0 7e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein MFS_1 PF07690.11 KUM60591.1 - 2.2e-25 89.1 37.5 2.2e-25 89.1 26.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Spb1_C PF07780.7 KUM60592.1 - 4.6e-70 235.4 37.4 4.6e-70 235.4 25.9 4.5 3 2 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 KUM60592.1 - 1.2e-54 184.1 8.0 1.2e-54 184.1 5.6 5.1 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 KUM60592.1 - 3.5e-54 183.5 0.0 6.3e-54 182.6 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF2854 PF11016.3 KUM60592.1 - 0.15 11.5 2.5 2.7 7.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2854) Zn_clus PF00172.13 KUM60594.1 - 5.3e-07 29.4 6.3 1.5e-06 28.0 4.3 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KUM60594.1 - 1.1e-05 24.4 1.7 3e-05 23.0 1.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain EF-hand_4 PF12763.2 KUM60595.1 - 0.00019 21.1 0.1 0.00036 20.2 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand HATPase_c_3 PF13589.1 KUM60595.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Fungal_trans PF04082.13 KUM60596.1 - 3.3e-18 65.5 3.6 6.4e-18 64.5 2.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KUM60596.1 - 4.7e-08 32.9 16.3 0.00037 20.6 2.1 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KUM60596.1 - 6.4e-08 32.5 6.8 1.4e-06 28.2 3.6 2.9 2 0 0 2 2 2 1 Zinc-finger double domain Zn_clus PF00172.13 KUM60596.1 - 1.5e-06 28.0 8.9 1.5e-06 28.0 6.2 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 KUM60596.1 - 0.0001 22.3 23.7 0.00019 21.5 1.8 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 KUM60596.1 - 0.015 15.4 0.6 0.015 15.4 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KUM60596.1 - 0.088 12.9 8.3 0.94 9.6 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Ras PF00071.17 KUM60597.1 - 1.5e-52 177.2 0.5 2.6e-38 130.9 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KUM60597.1 - 1.4e-16 61.0 0.0 5.5e-16 59.1 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KUM60597.1 - 1.2e-09 37.6 0.3 1.5e-07 30.7 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KUM60597.1 - 1.1e-06 28.5 0.0 2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KUM60597.1 - 7.2e-05 22.0 0.1 0.00013 21.2 0.0 1.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KUM60597.1 - 0.0002 20.8 0.6 0.97 8.8 0.0 3.0 2 1 1 3 3 3 2 Elongation factor Tu GTP binding domain cobW PF02492.14 KUM60597.1 - 0.0011 18.4 0.1 0.015 14.7 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 KUM60597.1 - 0.0016 17.6 0.1 0.003 16.7 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KUM60597.1 - 0.0017 18.4 0.0 0.0027 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KUM60597.1 - 0.0058 16.2 0.2 0.011 15.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 KUM60597.1 - 0.0072 15.8 0.5 0.16 11.4 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 KUM60597.1 - 0.011 15.5 0.6 0.017 14.7 0.0 1.5 2 0 0 2 2 2 0 Archaeal ATPase AAA_16 PF13191.1 KUM60597.1 - 0.012 15.5 0.0 0.066 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 KUM60597.1 - 0.023 14.4 0.0 0.047 13.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 KUM60597.1 - 0.024 14.3 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 NTPase SRPRB PF09439.5 KUM60597.1 - 0.036 13.2 0.0 0.054 12.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 KUM60597.1 - 0.037 13.4 0.2 0.071 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain Septin PF00735.13 KUM60597.1 - 0.038 12.9 0.0 0.071 12.1 0.0 1.5 1 0 0 1 1 1 0 Septin MobB PF03205.9 KUM60597.1 - 0.053 13.2 0.3 0.15 11.7 0.1 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KUM60597.1 - 0.083 12.5 0.1 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 NACHT domain Ecotin PF03974.8 KUM60597.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Ecotin EamA PF00892.15 KUM60598.1 - 9.2e-07 28.9 4.9 9.2e-07 28.9 3.4 3.2 3 1 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 KUM60598.1 - 6.1e-06 25.3 9.9 1.1e-05 24.5 6.9 1.3 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KUM60598.1 - 2e-05 24.2 25.5 0.0015 18.2 0.6 2.9 3 0 0 3 3 3 2 Triose-phosphate Transporter family DUF914 PF06027.7 KUM60598.1 - 0.00012 21.0 1.3 0.00012 21.0 0.9 2.0 2 1 1 3 3 3 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 KUM60598.1 - 0.00043 20.4 5.9 0.00043 20.4 4.1 3.8 3 2 0 4 4 4 1 Multidrug resistance efflux transporter PsbW PF07123.7 KUM60598.1 - 0.16 12.0 1.2 1 9.4 0.4 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) IDO PF01231.13 KUM60599.1 - 6.4e-33 113.8 0.1 3.3e-32 111.4 0.0 1.8 2 0 0 2 2 2 1 Indoleamine 2,3-dioxygenase Cyt-b5 PF00173.23 KUM60599.1 - 6.4e-13 48.2 0.0 1.9e-12 46.7 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain p450 PF00067.17 KUM60600.1 - 9.7e-53 179.3 0.0 1e-52 179.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 H_PPase PF03030.11 KUM60601.1 - 0.068 11.4 3.7 0.017 13.4 0.5 1.5 2 0 0 2 2 2 0 Inorganic H+ pyrophosphatase MARVEL PF01284.18 KUM60601.1 - 2.2 8.0 14.6 0.12 12.1 0.9 3.2 2 1 1 3 3 3 0 Membrane-associating domain Trp_DMAT PF11991.3 KUM60602.1 - 9.3e-15 54.6 0.3 4e-14 52.5 0.2 1.9 1 1 0 1 1 1 1 Tryptophan dimethylallyltransferase CDC27 PF09507.5 KUM60605.1 - 6.5 5.8 15.7 7.9 5.5 10.9 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Kei1 PF08552.6 KUM60605.1 - 6.6 6.3 5.5 22 4.6 3.8 1.7 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Peptidase_S76 PF13611.1 KUM60606.1 - 0.017 15.2 0.0 0.063 13.3 0.0 2.0 1 0 0 1 1 1 0 Serine peptidase of plant viral polyprotein, P1 YEATS PF03366.11 KUM60607.1 - 1.8e-21 75.6 0.3 3.2e-21 74.8 0.2 1.4 1 0 0 1 1 1 1 YEATS family Ran_BP1 PF00638.13 KUM60608.1 - 3.8e-45 152.8 0.7 4.4e-45 152.6 0.5 1.0 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 KUM60608.1 - 6.7e-06 25.7 0.6 4.3e-05 23.1 0.4 1.9 1 1 0 1 1 1 1 WH1 domain DUF1681 PF07933.9 KUM60608.1 - 0.095 12.2 0.3 0.11 12.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1681) MFS_1 PF07690.11 KUM60612.1 - 2.2e-34 118.7 44.4 2.2e-34 118.7 30.8 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_5 PF06946.6 KUM60612.1 - 0.058 13.5 2.7 0.65 10.2 0.5 3.3 2 1 0 2 2 2 0 Phage holin PH PF00169.24 KUM60613.1 - 2.9e-25 88.4 0.1 2.6e-11 43.6 0.0 2.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 KUM60613.1 - 2.3e-11 43.9 0.3 1.7e-05 25.0 0.0 3.5 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 KUM60613.1 - 6.9e-10 39.1 0.3 6.6e-05 23.0 0.0 4.0 2 2 0 2 2 2 2 Pleckstrin homology domain Glyco_transf_15 PF01793.11 KUM60614.1 - 9.5e-133 442.2 4.0 1.2e-132 441.8 2.8 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DOT1 PF08123.8 KUM60615.1 - 4.2e-77 258.0 0.0 5.7e-77 257.6 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 KUM60615.1 - 0.00028 20.8 0.0 0.00064 19.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM60615.1 - 0.0048 16.4 0.0 0.0093 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ATG16 PF08614.6 KUM60616.1 - 2.4e-52 177.5 15.9 2.7e-52 177.4 11.0 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) CCDC144C PF14915.1 KUM60616.1 - 0.0023 16.9 9.6 0.004 16.1 6.7 1.3 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region Spc7 PF08317.6 KUM60616.1 - 0.0047 15.6 7.2 0.009 14.7 5.0 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein IncA PF04156.9 KUM60616.1 - 0.011 15.3 12.8 0.012 15.2 8.2 1.4 1 1 0 1 1 1 0 IncA protein Nup54 PF13874.1 KUM60616.1 - 0.017 14.7 12.7 0.026 14.2 3.0 2.5 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 CENP-F_leu_zip PF10473.4 KUM60616.1 - 0.033 14.0 11.0 0.071 12.9 7.7 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sec2p PF06428.6 KUM60616.1 - 0.035 13.9 15.4 0.022 14.6 8.0 2.2 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Atg14 PF10186.4 KUM60616.1 - 0.061 12.2 10.3 0.099 11.5 7.1 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 MscS_porin PF12795.2 KUM60616.1 - 0.13 11.5 26.1 0.22 10.7 4.4 3.0 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain GAS PF13851.1 KUM60616.1 - 0.69 9.0 15.9 6.4 5.9 8.6 2.3 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF342 PF03961.8 KUM60616.1 - 0.81 8.0 5.0 1.2 7.5 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 KUM60616.1 - 0.87 8.5 14.4 0.056 12.4 6.6 1.4 2 0 0 2 2 2 0 Autophagy protein Apg6 Fez1 PF06818.10 KUM60616.1 - 0.87 9.5 16.8 0.13 12.2 4.1 2.4 1 1 1 2 2 2 0 Fez1 Fmp27_WPPW PF10359.4 KUM60616.1 - 1.5 7.1 8.2 1.2 7.5 4.0 1.6 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain V_ATPase_I PF01496.14 KUM60616.1 - 2 6.1 7.2 3 5.6 5.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 KUM60616.1 - 2.1 8.7 12.5 4.3 7.7 1.8 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF972) CCDC-167 PF15188.1 KUM60616.1 - 2.2 8.2 15.5 3.8 7.5 4.3 2.4 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF1664 PF07889.7 KUM60616.1 - 3.1 7.6 5.8 5.7 6.7 0.1 2.5 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Phage_Gp23 PF10669.4 KUM60616.1 - 4.4 7.4 9.7 10 6.2 3.1 2.4 1 1 1 2 2 2 0 Protein gp23 (Bacteriophage A118) YlqD PF11068.3 KUM60616.1 - 4.5 7.3 8.6 6.3 6.8 4.0 2.3 2 1 0 2 2 2 0 YlqD protein DivIVA PF05103.8 KUM60616.1 - 5.8 6.9 16.9 8.6 6.4 2.4 3.0 1 1 1 2 2 2 0 DivIVA protein Mnd1 PF03962.10 KUM60616.1 - 6.4 6.3 13.9 0.71 9.5 6.4 1.7 2 0 0 2 2 2 0 Mnd1 family Jnk-SapK_ap_N PF09744.4 KUM60616.1 - 6.8 6.6 11.7 42 4.0 8.1 2.1 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF4600 PF15372.1 KUM60616.1 - 9.5 6.4 14.6 2.8 8.1 7.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) TSC22 PF01166.13 KUM60616.1 - 9.5 6.2 7.5 2.2 8.2 0.6 2.9 1 1 2 3 3 3 0 TSC-22/dip/bun family Sterol_MT_C PF08498.5 KUM60618.1 - 2e-26 91.6 0.0 3.2e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 KUM60618.1 - 5.1e-22 78.1 0.0 1e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM60618.1 - 2.9e-18 65.8 0.0 4.5e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM60618.1 - 2.9e-13 50.0 0.0 5e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM60618.1 - 1.9e-11 43.9 0.0 3.4e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM60618.1 - 8.7e-11 42.3 0.0 3.5e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM60618.1 - 2.2e-10 40.8 0.0 4.6e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KUM60618.1 - 4.3e-10 39.1 0.0 7.3e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KUM60618.1 - 6.7e-08 32.5 0.0 1.9e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KUM60618.1 - 5.6e-07 28.9 0.0 7.9e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 KUM60618.1 - 0.0021 17.6 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 KUM60618.1 - 0.0038 16.6 0.0 0.0068 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.15 KUM60618.1 - 0.0059 15.6 0.0 0.0099 14.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.7 KUM60618.1 - 0.0077 15.6 0.0 0.02 14.2 0.0 1.7 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW NodS PF05401.6 KUM60618.1 - 0.0094 15.3 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.8 KUM60618.1 - 0.016 14.3 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_29 PF03141.11 KUM60618.1 - 0.026 12.8 0.0 0.04 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_15 PF09445.5 KUM60618.1 - 0.049 13.1 0.1 0.07 12.6 0.1 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.1 KUM60618.1 - 0.076 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 KUM60618.1 - 0.084 12.4 0.0 0.24 11.0 0.0 1.6 2 0 0 2 2 2 0 Hypothetical methyltransferase UPF0020 PF01170.13 KUM60618.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Glyco_hydro_17 PF00332.13 KUM60621.1 - 1.3e-07 30.9 3.9 6.6e-05 22.0 0.3 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 AP_endonuc_2 PF01261.19 KUM60621.1 - 0.023 13.9 0.0 0.039 13.2 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF2076 PF09849.4 KUM60621.1 - 0.6 10.1 5.8 1.2 9.1 4.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF4336 PF14234.1 KUM60622.1 - 2.4e-17 63.0 0.0 2.4e-13 49.9 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) Nse4_C PF08743.5 KUM60623.1 - 7.6e-33 112.4 0.2 2.7e-32 110.6 0.0 2.2 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 KUM60623.1 - 1.5e-17 63.1 0.1 4.5e-17 61.6 0.1 1.9 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE SMC_Nse1 PF07574.8 KUM60623.1 - 0.13 11.8 2.7 3.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Nse1 non-SMC component of SMC5-6 complex Ndc1_Nup PF09531.5 KUM60623.1 - 0.62 8.4 7.5 1 7.7 5.2 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-C3H1 PF10650.4 KUM60624.1 - 3.5e-13 48.7 0.5 5.2e-13 48.2 0.3 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain zf-DHHC PF01529.15 KUM60625.1 - 1.4e-24 86.4 12.2 6.7e-24 84.2 7.9 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Isy1 PF06246.7 KUM60626.1 - 6.1e-83 278.1 0.4 7.3e-83 277.8 0.3 1.1 1 0 0 1 1 1 1 Isy1-like splicing family Myosin_head PF00063.16 KUM60627.1 - 7.5e-246 817.5 0.1 4.4e-245 814.9 0.0 2.5 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 KUM60627.1 - 1.1e-33 116.0 278.9 1.1e-22 79.6 86.5 5.9 2 2 3 5 5 5 4 Myosin tail AAA_19 PF13245.1 KUM60627.1 - 0.071 12.8 0.0 0.22 11.2 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Myosin_N PF02736.14 KUM60627.1 - 0.071 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain Reo_sigmaC PF04582.7 KUM60627.1 - 2.2 7.3 87.0 0.14 11.3 4.7 9.9 4 3 5 10 10 10 0 Reovirus sigma C capsid protein MMR_HSR1 PF01926.18 KUM60629.1 - 2e-15 56.7 0.0 5.4e-15 55.3 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 KUM60629.1 - 1.8e-06 27.2 0.0 2.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 KUM60629.1 - 2.9e-06 26.6 0.1 4.3e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.11 KUM60629.1 - 2.5e-05 23.5 0.0 3.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 KUM60629.1 - 0.0011 18.4 0.0 0.0047 16.3 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Septin PF00735.13 KUM60629.1 - 0.0012 17.8 0.0 0.002 17.1 0.0 1.2 1 0 0 1 1 1 1 Septin MobB PF03205.9 KUM60629.1 - 0.0096 15.6 0.1 0.02 14.5 0.1 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KUM60629.1 - 0.014 15.6 0.0 0.037 14.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KUM60629.1 - 0.023 15.5 0.1 0.079 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.5 KUM60629.1 - 0.028 13.6 0.0 0.062 12.5 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 KUM60629.1 - 0.03 14.1 0.1 0.46 10.2 0.0 2.3 1 1 0 2 2 2 0 Dynamin family Miro PF08477.8 KUM60629.1 - 0.05 14.1 0.0 0.17 12.3 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein AAA_16 PF13191.1 KUM60629.1 - 0.07 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Arf PF00025.16 KUM60629.1 - 0.12 11.6 0.0 0.4 9.8 0.0 1.7 1 1 1 2 2 2 0 ADP-ribosylation factor family PI3Ka PF00613.15 KUM60630.1 - 2.9e-58 196.0 0.4 4.8e-58 195.3 0.3 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 KUM60630.1 - 2.1e-41 141.9 0.0 3.3e-39 134.7 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 KUM60630.1 - 1.6e-26 92.7 0.0 2.7e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 zf-H2C2_2 PF13465.1 KUM60631.1 - 1.5e-05 24.9 1.0 4.4e-05 23.5 0.7 1.8 1 0 0 1 1 1 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KUM60631.1 - 0.00023 21.2 7.4 0.0022 18.2 1.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KUM60631.1 - 0.00064 19.9 7.9 0.0046 17.2 1.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.7 KUM60631.1 - 0.079 13.0 1.5 0.15 12.2 1.0 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 KUM60631.1 - 0.83 10.0 5.3 14 6.1 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Septin PF00735.13 KUM60635.1 - 3.7e-123 410.0 0.2 3.7e-123 410.0 0.1 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KUM60635.1 - 4e-07 29.9 0.0 8.5e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KUM60635.1 - 5.6e-06 25.9 0.7 0.00022 20.7 0.0 2.7 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KUM60635.1 - 2.6e-05 23.4 0.2 9e-05 21.7 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KUM60635.1 - 0.00015 20.9 0.8 0.00039 19.5 0.0 2.0 2 0 0 2 2 2 1 AIG1 family ABC_tran PF00005.22 KUM60635.1 - 0.00025 21.3 2.6 0.022 15.0 0.0 3.0 2 1 0 2 2 2 1 ABC transporter AAA_10 PF12846.2 KUM60635.1 - 0.00036 20.0 0.3 0.0015 18.0 0.0 2.0 2 1 0 2 2 2 1 AAA-like domain Ras PF00071.17 KUM60635.1 - 0.0012 18.2 0.1 0.015 14.7 0.0 2.6 2 0 0 2 2 2 1 Ras family AAA_16 PF13191.1 KUM60635.1 - 0.0023 17.9 0.1 0.014 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KUM60635.1 - 0.003 17.6 0.1 0.012 15.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 KUM60635.1 - 0.0031 18.0 0.0 0.015 15.8 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 KUM60635.1 - 0.006 16.0 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KUM60635.1 - 0.02 14.3 0.0 0.02 14.3 0.0 2.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 KUM60635.1 - 0.026 14.0 0.5 4.2 6.8 0.0 3.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 KUM60635.1 - 0.053 13.0 0.3 0.12 11.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.21 KUM60635.1 - 0.072 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Exonuc_VII_L PF02601.10 KUM60635.1 - 0.11 11.6 3.0 0.22 10.6 2.1 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Dynamin_N PF00350.18 KUM60635.1 - 0.11 12.2 5.9 0.46 10.2 0.1 3.3 3 2 1 4 4 4 0 Dynamin family MobB PF03205.9 KUM60635.1 - 0.12 12.0 0.8 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KUM60635.1 - 0.13 12.4 0.2 0.55 10.4 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Strep_SA_rep PF06696.6 KUM60635.1 - 0.14 11.9 2.2 0.21 11.3 0.9 1.9 1 1 1 2 2 2 0 Streptococcal surface antigen repeat AAA_32 PF13654.1 KUM60635.1 - 0.19 10.3 9.6 0.43 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain IIGP PF05049.8 KUM60635.1 - 0.53 9.0 4.3 0.22 10.2 0.1 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) MASE1 PF05231.9 KUM60637.1 - 0.22 10.5 14.9 0.04 12.9 2.7 2.1 1 1 1 2 2 2 0 MASE1 Methyltransf_2 PF00891.13 KUM60638.1 - 9.4e-31 106.8 0.1 3e-30 105.1 0.1 1.7 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 KUM60638.1 - 0.00069 19.3 0.0 0.0019 17.9 0.0 1.8 1 0 0 1 1 1 1 Dimerisation domain HTH_27 PF13463.1 KUM60638.1 - 0.012 15.9 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain Rrf2 PF02082.15 KUM60638.1 - 0.15 12.2 0.0 0.65 10.1 0.0 2.0 3 0 0 3 3 3 0 Transcriptional regulator PfkB PF00294.19 KUM60639.1 - 5.5e-13 48.7 0.0 7e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase TPK_catalytic PF04263.11 KUM60640.1 - 1.7e-22 79.3 0.1 1.7e-18 66.4 0.0 3.1 2 1 0 2 2 2 2 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 KUM60640.1 - 1.4e-20 72.7 0.0 2.2e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Ribosomal_60s PF00428.14 KUM60640.1 - 0.028 14.8 2.2 0.028 14.8 1.5 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Med21 PF11221.3 KUM60640.1 - 0.89 9.5 7.6 37 4.2 5.3 2.3 1 1 0 1 1 1 0 Subunit 21 of Mediator complex CHCH PF06747.8 KUM60641.1 - 3.6e-08 33.1 4.1 5.9e-08 32.4 2.8 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 KUM60641.1 - 0.072 13.2 1.3 0.19 11.8 0.9 1.6 1 0 0 1 1 1 0 GCK domain SSrecog PF03531.9 KUM60642.1 - 2.3e-71 239.6 0.2 3.2e-70 235.9 0.2 2.6 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 KUM60642.1 - 7.8e-29 99.5 0.0 2.6e-27 94.6 0.0 2.8 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Rax2 PF12768.2 KUM60643.1 - 1e-100 336.6 9.2 5.8e-91 304.5 0.0 5.4 5 2 2 7 7 7 5 Cortical protein marker for cell polarity Fungal_trans_2 PF11951.3 KUM60644.1 - 3.7e-06 25.8 1.7 1.4e-05 23.8 1.2 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain SH3_3 PF08239.6 KUM60646.1 - 0.00036 20.6 0.2 0.00063 19.8 0.1 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain UPF0121 PF03661.8 KUM60647.1 - 2.8e-12 46.3 4.6 4e-12 45.8 3.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Mito_carr PF00153.22 KUM60648.1 - 8.2e-63 208.1 0.2 2.1e-21 75.4 0.0 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein Rho_N PF07498.7 KUM60649.1 - 0.036 13.8 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain ORC6 PF05460.8 KUM60649.1 - 0.11 11.5 2.9 0.15 11.1 2.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PALP PF00291.20 KUM60650.1 - 2.4e-05 23.7 0.0 2.7e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PLU-1 PF08429.6 KUM60651.1 - 3.8e-100 335.0 17.6 5e-97 324.7 11.9 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 KUM60651.1 - 1.9e-42 144.1 0.1 4.8e-42 142.7 0.1 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 KUM60651.1 - 4.5e-26 90.5 0.0 1.3e-25 89.0 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.12 KUM60651.1 - 7.5e-18 63.7 1.0 1.8e-17 62.5 0.7 1.7 1 0 0 1 1 1 1 jmjN domain PHD PF00628.24 KUM60651.1 - 1.3e-17 63.1 31.3 1.4e-09 37.4 5.5 3.5 3 0 0 3 3 3 2 PHD-finger zf-C5HC2 PF02928.11 KUM60651.1 - 1.7e-17 63.2 8.2 4.1e-17 61.9 5.7 1.7 1 0 0 1 1 1 1 C5HC2 zinc finger zf-PHD-like PF15446.1 KUM60651.1 - 3.7e-05 23.0 9.2 0.0004 19.7 1.0 2.7 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 KUM60651.1 - 0.001 18.3 2.6 0.001 18.3 1.8 3.0 3 0 0 3 3 3 1 PHD-finger Desulfoferrodox PF01880.13 KUM60651.1 - 0.018 15.2 0.3 0.045 14.0 0.2 1.7 1 0 0 1 1 1 0 Desulfoferrodoxin Olfactory_mark PF06554.7 KUM60651.1 - 0.056 12.9 0.1 9.3 5.7 0.0 2.5 2 0 0 2 2 2 0 Olfactory marker protein C1_3 PF07649.7 KUM60651.1 - 0.27 11.3 9.3 0.089 12.8 2.3 2.9 2 0 0 2 2 2 0 C1-like domain C1_1 PF00130.17 KUM60651.1 - 6.6 6.5 24.5 0.18 11.5 0.4 3.5 3 0 0 3 3 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TGT PF01702.13 KUM60652.1 - 1.2e-42 145.8 0.0 1.5e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase MTHFR PF02219.12 KUM60653.1 - 5.4e-95 317.7 0.0 7.5e-95 317.3 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase GIY-YIG PF01541.19 KUM60654.1 - 4.6e-08 33.3 0.0 1.3e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.3 KUM60654.1 - 4.2e-05 23.4 2.6 7.3e-05 22.6 1.8 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain PHD PF00628.24 KUM60654.1 - 0.0046 16.6 3.5 0.0046 16.6 2.5 1.8 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 KUM60654.1 - 0.01 15.5 4.2 0.031 13.9 1.0 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.1 KUM60654.1 - 0.034 14.2 0.7 0.074 13.1 0.5 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_2 PF13639.1 KUM60654.1 - 0.11 12.2 6.4 0.21 11.4 4.5 1.5 1 0 0 1 1 1 0 Ring finger domain Pro_CA PF00484.14 KUM60654.1 - 0.12 12.3 0.1 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Carbonic anhydrase C1_1 PF00130.17 KUM60654.1 - 0.21 11.3 1.9 0.31 10.8 0.4 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HypA PF01155.14 KUM60654.1 - 0.49 10.1 2.4 2.8 7.6 1.7 2.0 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_2 PF13240.1 KUM60654.1 - 1 8.9 4.2 8.4 6.0 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING-like PF08746.6 KUM60654.1 - 1.4 8.9 4.7 5.5 7.0 3.3 2.0 1 1 0 1 1 1 0 RING-like domain Thymidylate_kin PF02223.12 KUM60655.1 - 7.2e-48 162.4 0.0 8.2e-48 162.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.5 KUM60655.1 - 0.00034 19.9 0.2 0.00089 18.5 0.0 1.7 2 1 0 2 2 2 1 Chromatin associated protein KTI12 AAA_16 PF13191.1 KUM60655.1 - 0.028 14.4 0.1 0.056 13.4 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain NMT1 PF09084.6 KUM60656.1 - 9.4e-05 22.0 0.1 0.00026 20.6 0.0 1.9 2 0 0 2 2 2 1 NMT1/THI5 like Phosphonate-bd PF12974.2 KUM60656.1 - 0.0084 15.5 0.1 0.038 13.3 0.0 2.0 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Glyco_hydro_18 PF00704.23 KUM60657.1 - 5.8e-20 72.0 6.9 8.4e-20 71.5 4.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 IER PF05760.7 KUM60657.1 - 0.39 10.6 13.3 0.57 10.0 9.2 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) TFIIA PF03153.8 KUM60657.1 - 2.2 8.1 15.9 3 7.6 11.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mitofilin PF09731.4 KUM60657.1 - 3.9 6.0 11.5 5.1 5.6 7.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF2413 PF10310.4 KUM60657.1 - 4.1 6.1 16.2 7.9 5.1 11.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) E1-E2_ATPase PF00122.15 KUM60658.1 - 4.8e-75 251.5 0.2 5.4e-74 248.0 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KUM60658.1 - 1.4e-25 91.0 0.1 2.9e-25 89.9 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KUM60658.1 - 8.1e-14 52.2 0.0 1.6e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KUM60658.1 - 5.4e-08 32.1 0.0 1.1e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KUM60658.1 - 0.0021 17.6 0.0 0.013 15.0 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KUM60658.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit PQ-loop PF04193.9 KUM60659.1 - 7.2e-21 73.5 3.5 2.8e-13 49.1 0.2 2.6 2 0 0 2 2 2 2 PQ loop repeat MFS_1 PF07690.11 KUM60661.1 - 8.8e-39 133.2 30.5 8.8e-39 133.2 21.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily SpoVAB PF13782.1 KUM60661.1 - 0.0084 16.0 2.9 0.01 15.8 0.3 2.3 2 0 0 2 2 2 1 Stage V sporulation protein AB Glyco_hydro_31 PF01055.21 KUM60662.1 - 2e-144 481.7 7.6 2e-144 481.7 5.3 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KUM60662.1 - 5.7e-23 80.5 0.1 2e-22 78.8 0.1 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like Sugar_tr PF00083.19 KUM60663.1 - 4.9e-41 140.7 24.1 8.5e-41 139.9 16.7 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM60663.1 - 7.6e-37 126.8 47.6 1.3e-31 109.5 20.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily HD PF01966.17 KUM60665.1 - 5.3e-05 23.2 0.4 0.00011 22.1 0.3 1.6 1 0 0 1 1 1 1 HD domain CN_hydrolase PF00795.17 KUM60666.1 - 9.8e-22 77.2 0.0 3e-21 75.6 0.0 1.7 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Fungal_trans PF04082.13 KUM60667.1 - 5.6e-12 45.0 1.0 9e-12 44.4 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidohydro_4 PF13147.1 KUM60668.1 - 2e-25 90.3 0.0 3.5e-12 46.9 0.0 3.1 2 1 1 3 3 3 3 Amidohydrolase Amidohydro_1 PF01979.15 KUM60668.1 - 5.6e-15 55.8 0.0 8.9e-14 51.8 0.0 2.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KUM60668.1 - 6e-14 51.6 1.7 1.6e-13 50.2 1.2 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KUM60668.1 - 7.2e-10 38.6 0.0 5.3e-05 22.6 0.0 3.2 3 1 0 3 3 3 2 Amidohydrolase family Urease_alpha PF00449.15 KUM60668.1 - 0.11 12.6 0.4 0.21 11.7 0.3 1.5 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain NDK PF00334.14 KUM60669.1 - 3e-54 182.4 0.0 3.9e-54 182.0 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase FLILHELTA PF10306.4 KUM60670.1 - 6.2e-26 90.2 0.0 1e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 KUM60670.1 - 0.0023 18.1 0.0 0.0029 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Amidohydro_4 PF13147.1 KUM60672.1 - 6.1e-20 72.3 4.0 2.8e-17 63.6 0.0 3.7 3 1 0 3 3 3 2 Amidohydrolase Amidohydro_5 PF13594.1 KUM60672.1 - 7.4e-11 41.7 0.0 7.6e-09 35.2 0.0 2.7 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 KUM60672.1 - 9.7e-11 41.8 1.3 6.1e-09 35.9 0.0 2.4 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.6 KUM60672.1 - 6.5e-08 32.1 0.3 4.5e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Ank_2 PF12796.2 KUM60673.1 - 1.6e-30 105.2 0.0 1.2e-09 38.4 0.0 5.1 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 KUM60673.1 - 7.5e-24 82.3 0.0 1.5e-06 27.6 0.1 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 KUM60673.1 - 1.4e-22 79.6 0.2 1.8e-08 34.6 0.1 5.7 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM60673.1 - 1.1e-19 70.0 3.0 3.6e-07 30.1 0.1 5.9 5 1 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM60673.1 - 2e-14 52.2 0.8 0.00031 20.6 0.0 7.0 7 0 0 7 7 7 2 Ankyrin repeat NACHT PF05729.7 KUM60673.1 - 3.2e-07 30.1 0.0 1e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KUM60673.1 - 0.0013 18.7 0.0 0.0069 16.3 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.9 KUM60673.1 - 0.082 11.8 0.0 3.4 6.5 0.0 2.5 2 0 0 2 2 2 0 KAP family P-loop domain RNA_helicase PF00910.17 KUM60673.1 - 0.16 12.1 0.1 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase POP1 PF06978.6 KUM60674.1 - 0.5 10.0 9.2 0.43 10.2 4.8 1.9 2 0 0 2 2 2 0 Ribonucleases P/MRP protein subunit POP1 DUF3906 PF13046.1 KUM60674.1 - 0.8 9.3 3.4 21 4.8 1.5 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3906) Abhydrolase_6 PF12697.2 KUM60675.1 - 3.7e-25 89.1 2.9 8.6e-25 87.9 2.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM60675.1 - 5.5e-09 35.9 0.0 8.3e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM60675.1 - 4.4e-06 26.4 0.0 5.9e-05 22.7 0.0 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 KUM60675.1 - 0.031 13.8 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Thioesterase PF00975.15 KUM60675.1 - 0.035 14.3 1.2 0.075 13.2 0.8 1.8 1 1 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.8 KUM60675.1 - 0.047 13.2 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein MFS_1 PF07690.11 KUM60676.1 - 1.3e-35 122.7 25.9 2e-35 122.1 17.9 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily FAD_binding_3 PF01494.14 KUM60677.1 - 1.5e-11 44.0 0.1 3.9e-11 42.5 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KUM60677.1 - 9e-09 34.6 1.9 2.1e-06 26.9 0.1 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KUM60677.1 - 3.9e-05 23.5 0.0 0.0001 22.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KUM60677.1 - 0.0021 17.8 0.2 0.0059 16.3 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KUM60677.1 - 0.0035 17.2 0.0 0.0063 16.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KUM60677.1 - 0.019 14.0 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 KUM60677.1 - 0.023 13.3 1.3 0.1 11.1 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.9 KUM60677.1 - 0.055 11.9 0.0 0.13 10.7 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.19 KUM60677.1 - 0.4 9.4 3.8 0.54 9.0 2.6 1.4 1 1 0 1 1 1 0 FAD binding domain Lipase_GDSL_2 PF13472.1 KUM60678.1 - 7.8e-19 68.4 0.2 1.2e-18 67.9 0.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KUM60678.1 - 1.8e-15 57.4 0.1 3.5e-15 56.4 0.1 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MFS_1 PF07690.11 KUM60679.1 - 2.1e-33 115.4 29.0 2.1e-33 115.4 20.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3445 PF11927.3 KUM60680.1 - 1.7e-59 201.1 0.0 2.1e-59 200.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Fungal_trans PF04082.13 KUM60681.1 - 3e-17 62.3 0.4 4.9e-17 61.6 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM60681.1 - 1.6e-10 40.6 8.3 3e-10 39.8 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amido_AtzD_TrzD PF09663.5 KUM60681.1 - 0.042 12.4 0.1 0.064 11.8 0.1 1.1 1 0 0 1 1 1 0 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) p450 PF00067.17 KUM60682.1 - 1.7e-34 119.1 0.0 1.8e-34 119.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KUM60683.1 - 1.7e-34 119.0 28.3 2.1e-34 118.8 19.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM60683.1 - 1.4e-07 30.4 9.5 1.4e-07 30.4 6.6 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter NUP PF06516.6 KUM60684.1 - 9.3e-130 432.0 0.2 1.1e-129 431.8 0.1 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) DUF4440 PF14534.1 KUM60685.1 - 1.7e-07 31.3 0.0 2e-07 31.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 KUM60685.1 - 0.084 13.2 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain Aldo_ket_red PF00248.16 KUM60686.1 - 1.3e-73 247.2 0.0 1.5e-73 247.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_Tnp_1 PF01527.15 KUM60686.1 - 0.15 12.0 0.1 5.3 7.0 0.0 3.1 3 1 0 3 3 3 0 Transposase Fungal_trans PF04082.13 KUM60687.1 - 6.1e-05 22.0 0.1 0.00012 21.0 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM60687.1 - 0.086 12.7 14.5 0.21 11.5 10.0 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HSP70 PF00012.15 KUM60689.1 - 0.00011 20.3 0.1 0.0013 16.7 0.0 2.4 2 1 0 2 2 2 2 Hsp70 protein AMP-binding PF00501.23 KUM60690.1 - 0 1044.2 0.9 6.4e-90 301.5 0.0 4.3 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 KUM60690.1 - 2.5e-114 381.2 0.0 1.1e-32 113.1 0.2 6.0 4 2 0 4 4 4 4 Condensation domain PP-binding PF00550.20 KUM60690.1 - 3.3e-33 113.7 0.4 1.2e-10 41.5 0.0 4.8 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KUM60690.1 - 1.9e-18 67.1 4.2 0.0002 22.2 0.1 5.8 5 0 0 5 5 5 4 AMP-binding enzyme C-terminal domain SelA PF03841.8 KUM60690.1 - 2.7 6.6 0.0 5.8 5.5 0.0 1.4 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase PEP_mutase PF13714.1 KUM60691.1 - 5.1e-44 150.2 0.0 6e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 KUM60691.1 - 9.4e-23 80.2 0.1 1.4e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Isocitrate lyase family FAD_binding_4 PF01565.18 KUM60693.1 - 1e-31 109.2 6.7 1.9e-31 108.3 4.7 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KUM60693.1 - 1.5e-11 43.9 0.1 3e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Aldedh PF00171.17 KUM60694.1 - 5.1e-164 545.9 0.1 5.8e-164 545.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KUM60694.1 - 0.00087 18.1 0.0 0.0014 17.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Pec_lyase_C PF00544.14 KUM60695.1 - 1.6e-43 148.5 8.1 2.2e-43 148.0 5.6 1.2 1 0 0 1 1 1 1 Pectate lyase 2OG-FeII_Oxy PF03171.15 KUM60696.1 - 1.2e-18 67.2 0.0 2.3e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KUM60696.1 - 1.8e-16 60.7 0.0 4.1e-16 59.5 0.0 1.6 1 1 1 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal Tautomerase_3 PF14832.1 KUM60697.1 - 1.2e-51 174.3 0.1 1.3e-51 174.1 0.1 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.16 KUM60697.1 - 0.12 11.9 0.0 0.41 10.2 0.0 1.8 2 0 0 2 2 2 0 Tautomerase enzyme Epimerase PF01370.16 KUM60698.1 - 8.7e-20 71.1 0.0 1.3e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KUM60698.1 - 7.7e-14 51.0 0.0 5.1e-13 48.3 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KUM60698.1 - 1.6e-12 47.8 0.1 1.8e-11 44.3 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 KUM60698.1 - 2.8e-08 33.2 0.0 1.7e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family NAD_binding_4 PF07993.7 KUM60698.1 - 6.8e-07 28.4 0.1 3.6e-05 22.8 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KUM60698.1 - 1.5e-06 28.2 0.0 5.1e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KUM60698.1 - 0.00033 19.6 0.0 0.0024 16.8 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 KUM60698.1 - 0.073 12.7 0.1 0.89 9.1 0.1 2.2 1 1 0 1 1 1 0 KR domain zf-CCCH PF00642.19 KUM60699.1 - 2.3e-19 68.5 29.4 1.7e-06 27.5 0.8 5.2 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 KUM60699.1 - 0.046 13.1 3.7 0.65 9.5 0.1 3.1 2 0 0 2 2 2 0 Putative zinc-finger domain zf-CCCH_2 PF14608.1 KUM60699.1 - 0.39 10.7 0.1 0.39 10.7 0.1 5.0 5 0 0 5 5 5 0 Zinc finger C-x8-C-x5-C-x3-H type Aldo_ket_red PF00248.16 KUM60700.1 - 3.4e-63 213.1 0.0 4.1e-63 212.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_psq PF05225.11 KUM60700.1 - 0.015 14.8 1.3 14 5.3 0.0 4.4 4 0 0 4 4 4 0 helix-turn-helix, Psq domain YCII PF03795.9 KUM60701.1 - 2.6e-07 30.7 0.0 3.2e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain Flavodoxin_4 PF12682.2 KUM60701.1 - 0.081 12.2 0.1 0.087 12.1 0.1 1.2 1 1 0 1 1 1 0 Flavodoxin DUF2374 PF09574.5 KUM60702.1 - 0.084 12.5 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (Duf2374) Mucin PF01456.12 KUM60702.1 - 0.39 10.4 9.8 0.51 10.1 6.8 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Tir_receptor_C PF07489.6 KUM60702.1 - 0.77 9.4 4.4 0.86 9.3 3.1 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Dicty_REP PF05086.7 KUM60702.1 - 3.9 5.1 5.3 4.8 4.8 3.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RNase_T PF00929.19 KUM60703.1 - 4.3e-22 79.1 0.0 5.4e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 KUM60703.1 - 0.0031 17.0 0.0 0.007 15.8 0.0 1.7 1 1 0 1 1 1 1 3'-5' exonuclease Aldedh PF00171.17 KUM60706.1 - 4.2e-144 480.3 0.0 5e-144 480.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KUM60706.1 - 3.9e-06 25.8 0.0 5.9e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Glyco_hydro_18 PF00704.23 KUM60708.1 - 1.1e-80 271.6 0.0 1.3e-80 271.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3142 PF11340.3 KUM60708.1 - 5.2e-06 26.2 0.0 7.6e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) DUF218 PF02698.12 KUM60708.1 - 0.1 12.0 0.1 0.44 10.0 0.0 2.1 3 0 0 3 3 3 0 DUF218 domain LisH PF08513.6 KUM60709.1 - 8.8e-05 22.1 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 LisH TFIID_90kDa PF04494.10 KUM60709.1 - 0.0014 18.6 0.0 0.0037 17.3 0.0 1.6 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit WD40 PF00400.27 KUM60710.1 - 3.8e-52 172.3 28.1 3.6e-10 39.3 0.7 7.1 8 0 0 8 8 8 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 KUM60710.1 - 5.5e-25 88.0 0.0 7.8e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 KUM60710.1 - 3.6e-07 28.7 4.6 0.0015 16.7 0.0 3.3 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Nbas_N PF15492.1 KUM60710.1 - 0.00095 18.3 0.4 0.45 9.5 0.2 3.1 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 KUM60710.1 - 0.0028 16.4 0.4 2.6 6.7 0.0 3.7 2 1 1 3 3 3 2 Nup133 N terminal like eIF2A PF08662.6 KUM60710.1 - 0.0059 16.3 0.3 0.038 13.6 0.1 2.3 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A DUF4550 PF15084.1 KUM60710.1 - 0.14 12.2 0.4 1.2 9.2 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4550) Abhydrolase_6 PF12697.2 KUM60711.1 - 3.7e-21 76.0 0.1 5.6e-21 75.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM60711.1 - 9.8e-08 31.8 0.0 2.3e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM60711.1 - 4.9e-05 22.9 0.1 0.053 13.0 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Lipase_3 PF01764.20 KUM60711.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 KUM60711.1 - 0.12 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF4026 PF13218.1 KUM60711.1 - 0.17 10.7 0.0 4.7 5.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4026) Fungal_trans PF04082.13 KUM60712.1 - 3e-11 42.6 0.0 4.8e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ECH PF00378.15 KUM60713.1 - 1.4e-28 99.7 0.1 2.7e-28 98.7 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Acyl-CoA_dh_1 PF00441.19 KUM60714.1 - 4e-17 62.6 0.0 1.6e-16 60.7 0.0 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KUM60714.1 - 2.2e-06 27.0 0.1 2.4e-05 23.7 0.0 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Dala_Dala_lig_C PF07478.8 KUM60715.1 - 5.5e-28 97.7 0.0 7.2e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.1 KUM60715.1 - 9.9e-11 41.6 0.0 3e-10 40.1 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KUM60715.1 - 0.00027 20.8 0.0 0.00048 20.0 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KUM60715.1 - 0.0069 15.1 0.0 0.025 13.3 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.14 KUM60715.1 - 0.0077 15.8 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Fungal_trans PF04082.13 KUM60716.1 - 2.4e-09 36.4 0.1 3.8e-09 35.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AAT PF03417.11 KUM60717.1 - 4.4e-13 49.1 0.0 1.6e-12 47.4 0.0 1.8 1 1 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Peptidase_C54 PF03416.14 KUM60717.1 - 0.04 13.0 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C54 PIG-F PF06699.6 KUM60718.1 - 1e-51 175.6 5.0 1.4e-51 175.1 3.5 1.2 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Gly-zipper_YMGG PF13441.1 KUM60718.1 - 0.0025 17.2 0.1 0.0067 15.9 0.1 1.7 1 1 0 1 1 1 1 YMGG-like Gly-zipper DUF4310 PF14187.1 KUM60718.1 - 0.025 14.0 0.5 0.041 13.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4310) DUF3169 PF11368.3 KUM60718.1 - 0.11 11.7 0.0 2 7.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Gly-zipper_Omp PF13488.1 KUM60718.1 - 0.18 11.4 6.3 2.4 7.8 0.2 2.3 2 0 0 2 2 2 0 Glycine zipper DUF1097 PF06496.6 KUM60718.1 - 0.19 11.5 8.0 1.3 8.8 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1097) Rick_17kDa_Anti PF05433.10 KUM60718.1 - 2.4 7.8 8.8 2.4 7.8 0.2 2.4 2 0 0 2 2 2 0 Glycine zipper 2TM domain Fungal_trans PF04082.13 KUM60719.1 - 1.2e-05 24.3 0.0 1.3e-05 24.2 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2417 PF10329.4 KUM60720.1 - 2e-85 285.8 0.3 2.7e-85 285.4 0.2 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 KUM60720.1 - 4.3e-08 33.3 0.8 7.9e-08 32.4 0.6 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family ABC2_membrane_3 PF12698.2 KUM60720.1 - 7.6 5.4 10.4 11 4.9 7.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein NPL4 PF05021.10 KUM60721.1 - 1.7e-123 411.6 0.0 1.6e-116 388.7 0.0 2.1 1 1 1 2 2 2 2 NPL4 family zf-NPL4 PF05020.10 KUM60721.1 - 1.4e-70 235.6 0.1 2.2e-70 235.0 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 KUM60721.1 - 7.2e-05 22.9 0.1 0.0016 18.6 0.0 2.8 2 1 0 2 2 2 1 Nuclear pore localisation protein NPL4 Flavodoxin_1 PF00258.20 KUM60722.1 - 3.1e-10 40.2 0.1 4.4e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 KUM60722.1 - 1.3e-07 31.2 0.0 1.7e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 KUM60722.1 - 2.3e-07 30.5 0.0 2.9e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 KUM60722.1 - 0.024 14.6 0.0 0.07 13.1 0.0 1.7 1 1 1 2 2 2 0 Flavodoxin domain Ig_J_chain PF15097.1 KUM60723.1 - 0.017 14.7 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin J chain SnoaL_2 PF12680.2 KUM60724.1 - 6.4e-06 26.5 0.2 8.3e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain LEH PF07858.7 KUM60724.1 - 0.00077 19.4 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain RcsC PF09456.5 KUM60724.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 RcsC Alpha-Beta-Loop (ABL) Helicase_C PF00271.26 KUM60725.1 - 1.4e-19 69.7 0.2 6e-19 67.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KUM60725.1 - 1.5e-19 70.1 0.0 5.7e-19 68.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KUM60725.1 - 1.6e-18 67.2 0.0 3.4e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KUM60725.1 - 0.058 12.3 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 KUM60725.1 - 0.082 13.0 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KUM60725.1 - 0.1 12.0 0.0 2.7 7.3 0.0 2.5 1 1 1 2 2 2 0 AAA-like domain Macoilin PF09726.4 KUM60726.1 - 1.4 7.1 10.4 1.4 7.0 7.2 1.0 1 0 0 1 1 1 0 Transmembrane protein DNA_pol_viral_N PF00242.12 KUM60726.1 - 4.1 6.3 6.8 4.3 6.2 4.7 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain F_actin_cap_B PF01115.12 KUM60727.1 - 8e-107 355.9 0.0 1.1e-106 355.5 0.0 1.2 1 0 0 1 1 1 1 F-actin capping protein, beta subunit HD PF01966.17 KUM60727.1 - 0.00071 19.5 0.1 0.0027 17.7 0.1 2.0 2 1 0 2 2 2 1 HD domain Med11 PF10280.4 KUM60728.1 - 1.9e-34 118.1 0.0 2.4e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein SP_C-Propep PF08999.5 KUM60729.1 - 0.11 12.0 0.1 0.25 10.8 0.1 1.6 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide PUF PF00806.14 KUM60730.1 - 6.8e-61 198.4 11.8 7e-10 37.8 0.2 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF260 PF03195.9 KUM60730.1 - 0.049 13.9 1.4 4.3 7.6 0.1 4.2 4 2 0 4 4 4 0 Protein of unknown function DUF260 DUF234 PF03008.9 KUM60730.1 - 0.26 11.4 0.9 1.8 8.7 0.1 2.5 3 0 0 3 3 3 0 Archaea bacterial proteins of unknown function cwf21 PF08312.7 KUM60731.1 - 6.6e-15 54.6 23.6 6.6e-15 54.6 16.3 2.6 2 1 0 2 2 2 1 cwf21 domain Paf1 PF03985.8 KUM60731.1 - 7.4 5.2 14.9 10 4.6 10.3 1.2 1 0 0 1 1 1 0 Paf1 DUF3402 PF11882.3 KUM60731.1 - 7.7 5.4 7.9 10 5.0 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) HA2 PF04408.18 KUM60732.1 - 3.2e-21 75.2 0.0 1.3e-20 73.3 0.0 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KUM60732.1 - 4.1e-14 52.1 0.0 1.5e-13 50.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 KUM60732.1 - 2.2e-10 40.3 0.0 8.3e-10 38.4 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 KUM60732.1 - 3.8e-08 33.0 0.0 6e-07 29.1 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KUM60732.1 - 0.00097 19.2 0.3 0.0047 17.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KUM60732.1 - 0.021 13.7 0.0 0.046 12.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 KUM60732.1 - 0.047 13.3 3.2 0.35 10.5 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase PhoH PF02562.11 KUM60732.1 - 0.12 11.5 0.0 0.26 10.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.1 KUM60732.1 - 0.15 12.4 0.0 0.15 12.4 0.0 3.9 4 1 0 4 4 4 0 AAA domain AAA_14 PF13173.1 KUM60732.1 - 0.17 11.7 1.1 1.1 9.1 0.1 2.7 2 1 0 2 2 2 0 AAA domain ResIII PF04851.10 KUM60732.1 - 1.4 8.7 0.0 1.4 8.7 0.0 3.8 5 0 0 5 5 5 0 Type III restriction enzyme, res subunit TFIID_20kDa PF03847.8 KUM60733.1 - 0.0078 16.4 0.1 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A COPI_C PF06957.6 KUM60733.1 - 2.2 6.6 8.5 3.7 5.9 5.9 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus ABC2_membrane PF01061.19 KUM60734.1 - 3.4e-86 287.7 55.0 1.2e-46 158.5 13.3 3.0 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 KUM60734.1 - 8.1e-39 133.0 0.0 3.6e-20 72.6 0.0 2.8 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KUM60734.1 - 5.3e-31 106.3 2.5 4.9e-26 90.3 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KUM60734.1 - 1.5e-07 31.3 0.1 6.4e-07 29.3 0.1 2.1 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal cobW PF02492.14 KUM60734.1 - 1.1e-06 28.2 0.4 0.00016 21.1 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 KUM60734.1 - 8.7e-06 25.7 0.1 0.0017 18.3 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KUM60734.1 - 1e-05 25.4 0.0 0.008 16.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KUM60734.1 - 1.6e-05 25.0 1.4 0.077 12.9 0.1 3.7 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.1 KUM60734.1 - 2.8e-05 23.6 0.3 0.13 11.6 0.2 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KUM60734.1 - 4e-05 23.6 0.2 0.0065 16.4 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KUM60734.1 - 4.5e-05 23.5 0.0 0.047 13.8 0.0 3.1 3 0 0 3 3 2 1 AAA domain UPF0079 PF02367.12 KUM60734.1 - 7.7e-05 22.3 2.0 0.1 12.2 0.4 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 KUM60734.1 - 0.00012 21.2 0.1 0.0013 17.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 KUM60734.1 - 0.00052 19.5 0.2 1 8.7 0.2 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_17 PF13207.1 KUM60734.1 - 0.00062 20.5 0.0 0.019 15.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KUM60734.1 - 0.001 18.5 0.5 0.23 11.0 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 KUM60734.1 - 0.0011 18.6 0.9 0.11 12.0 0.2 2.5 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.1 KUM60734.1 - 0.0026 18.0 3.5 0.011 16.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain SMC_N PF02463.14 KUM60734.1 - 0.0039 16.4 0.1 0.052 12.7 0.0 2.7 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA PF00004.24 KUM60734.1 - 0.0045 17.1 0.0 4.1 7.6 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 KUM60734.1 - 0.0058 17.1 0.4 0.4 11.1 0.0 3.1 3 0 0 3 3 2 1 Miro-like protein MMR_HSR1 PF01926.18 KUM60734.1 - 0.0063 16.4 0.0 0.099 12.6 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_24 PF13479.1 KUM60734.1 - 0.01 15.4 0.5 0.44 10.0 0.2 2.3 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 KUM60734.1 - 0.015 14.1 0.0 3 6.6 0.1 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.1 KUM60734.1 - 0.034 13.9 2.8 2.1 8.1 0.1 2.7 2 0 0 2 2 2 0 Part of AAA domain NB-ARC PF00931.17 KUM60734.1 - 0.045 12.5 0.5 6.2 5.5 0.2 2.6 2 0 0 2 2 2 0 NB-ARC domain APS_kinase PF01583.15 KUM60734.1 - 0.062 12.9 0.1 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_15 PF13175.1 KUM60734.1 - 0.075 12.0 0.0 11 4.9 0.0 2.3 1 1 1 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.18 KUM60734.1 - 0.1 12.4 0.0 0.94 9.2 0.0 2.7 2 0 0 2 2 2 0 Dynamin family Septin PF00735.13 KUM60734.1 - 0.1 11.5 0.5 0.27 10.2 0.1 1.8 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.4 KUM60734.1 - 0.11 11.9 1.0 0.52 9.7 0.3 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 KUM60734.1 - 0.31 10.4 2.1 3.1 7.1 0.1 2.3 2 0 0 2 2 2 0 AAA-like domain Zeta_toxin PF06414.7 KUM60734.1 - 0.36 9.8 5.6 0.53 9.3 0.2 2.8 3 0 0 3 3 3 0 Zeta toxin DUF2085 PF09858.4 KUM60734.1 - 5.1 7.2 8.9 1.8 8.7 0.1 4.0 4 0 0 4 4 3 0 Predicted membrane protein (DUF2085) CDP-OH_P_transf PF01066.16 KUM60735.1 - 6.1e-17 61.7 4.6 6.1e-17 61.7 3.2 1.6 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase MFS_1_like PF12832.2 KUM60735.1 - 0.043 13.6 0.0 2.2 8.1 0.0 2.5 2 0 0 2 2 2 0 MFS_1 like family Phosphodiest PF01663.17 KUM60736.1 - 3.2e-14 53.0 0.7 5.5e-14 52.2 0.5 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 KUM60736.1 - 3.5e-07 29.8 0.2 6.1e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 KUM60736.1 - 9.1e-06 25.0 0.1 1.7e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Sulfatase Peptidase_M22 PF00814.20 KUM60737.1 - 2.8e-84 282.7 0.0 3.2e-84 282.5 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family CmcH_NodU PF02543.10 KUM60737.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase Tyr-DNA_phospho PF06087.7 KUM60738.1 - 1.4e-69 234.8 0.0 2.1e-69 234.2 0.0 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 KUM60738.1 - 1.6e-05 24.6 0.0 0.012 15.3 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain UIM PF02809.15 KUM60738.1 - 0.0002 20.6 9.4 0.00071 18.9 0.1 3.1 3 0 0 3 3 3 2 Ubiquitin interaction motif 3HBOH PF10605.4 KUM60738.1 - 0.023 12.8 0.7 1.2 7.1 0.4 2.1 2 0 0 2 2 2 0 3HB-oligomer hydrolase (3HBOH) Glyco_hydro_16 PF00722.16 KUM60739.1 - 3e-42 144.0 4.4 3e-42 144.0 3.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 CIA30 PF08547.7 KUM60739.1 - 0.018 14.8 0.4 0.034 14.0 0.3 1.5 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) Zn_clus PF00172.13 KUM60740.1 - 3.6e-07 29.9 12.1 3.6e-07 29.9 8.4 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KUM60740.1 - 5.9e-07 28.6 0.3 1.2e-06 27.6 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain RseC_MucC PF04246.7 KUM60740.1 - 0.064 12.8 2.4 0.17 11.4 1.6 1.6 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC DUF1667 PF07892.6 KUM60740.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1667) DUF3384 PF11864.3 KUM60741.1 - 9e-98 327.7 1.1 9e-98 327.7 0.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 KUM60741.1 - 1.2e-49 168.2 0.0 2.4e-49 167.2 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 KUM60741.1 - 9.9e-32 110.3 0.0 1.3e-29 103.4 0.0 2.7 3 0 0 3 3 3 2 Tuberin CTP_synth_N PF06418.9 KUM60742.1 - 3.6e-117 390.3 0.1 4.8e-117 389.9 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 KUM60742.1 - 9e-53 178.5 0.0 1.5e-52 177.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KUM60742.1 - 3.9e-07 29.7 0.0 9e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 KUM60742.1 - 0.001 18.5 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CAS_CSE1 PF03378.10 KUM60743.1 - 4.5e-185 615.0 0.7 1e-184 613.8 0.5 1.6 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 KUM60743.1 - 7.3e-157 521.6 1.7 1.1e-156 521.1 1.2 1.2 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 KUM60743.1 - 6.1e-14 51.7 0.2 3.5e-13 49.2 0.1 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 KUM60743.1 - 0.0024 18.1 0.1 0.15 12.3 0.0 3.1 3 0 0 3 3 3 1 HEAT repeats DUF1529 PF07485.6 KUM60743.1 - 0.0029 17.3 0.0 0.05 13.3 0.0 2.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1259) Xpo1 PF08389.7 KUM60743.1 - 0.017 15.0 3.9 0.23 11.3 0.0 3.9 5 0 0 5 5 5 0 Exportin 1-like protein RF-1 PF00472.15 KUM60744.1 - 1.7e-26 92.2 1.1 2.8e-26 91.5 0.8 1.2 1 0 0 1 1 1 1 RF-1 domain E3_binding PF02817.12 KUM60744.1 - 0.06 12.9 0.1 0.17 11.5 0.1 1.7 1 0 0 1 1 1 0 e3 binding domain FAM117 PF15388.1 KUM60747.1 - 0.43 9.7 7.4 0.57 9.3 5.1 1.1 1 0 0 1 1 1 0 Protein Family FAM117 DUF566 PF04484.7 KUM60747.1 - 0.51 9.8 4.7 0.55 9.6 3.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Herpes_capsid PF06112.6 KUM60747.1 - 2.7 8.0 9.3 4 7.4 6.5 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein BTB PF00651.26 KUM60748.1 - 7.7e-14 51.6 0.2 2.2e-13 50.1 0.1 1.9 2 0 0 2 2 2 1 BTB/POZ domain GlnD_UR_UTase PF08335.6 KUM60748.1 - 0.0084 15.9 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 GlnD PII-uridylyltransferase SNF2_N PF00176.18 KUM60749.1 - 3.8e-56 190.0 0.1 9.6e-56 188.7 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-C3HC4 PF00097.20 KUM60749.1 - 7.5e-08 31.9 7.3 2.4e-07 30.2 5.1 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KUM60749.1 - 1e-06 28.4 9.8 2.7e-06 27.1 6.8 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KUM60749.1 - 2.7e-06 26.9 7.1 7.3e-06 25.5 4.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KUM60749.1 - 0.00012 21.7 7.7 0.00012 21.7 5.3 1.8 2 0 0 2 2 1 1 zinc-RING finger domain Nucleoplasmin PF03066.10 KUM60749.1 - 0.00012 21.5 0.2 0.00035 20.0 0.1 1.7 1 0 0 1 1 1 1 Nucleoplasmin zf-C3HC4_2 PF13923.1 KUM60749.1 - 0.00018 21.4 8.9 0.00054 19.9 6.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KUM60749.1 - 0.0004 20.4 4.4 0.0011 19.0 3.0 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 KUM60749.1 - 0.014 15.2 6.9 0.033 14.0 4.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 KUM60749.1 - 0.015 14.8 4.8 0.035 13.6 3.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 TPR_2 PF07719.12 KUM60749.1 - 0.064 13.1 0.2 0.23 11.4 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Helicase_C PF00271.26 KUM60749.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.8 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Acyltransferase PF01553.16 KUM60749.1 - 0.15 11.4 0.0 0.38 10.1 0.0 1.6 1 0 0 1 1 1 0 Acyltransferase zf-RING_UBOX PF13445.1 KUM60749.1 - 0.76 9.5 4.9 2.7 7.7 3.4 2.0 1 0 0 1 1 1 0 RING-type zinc-finger DnaJ PF00226.26 KUM60750.1 - 4.1e-11 42.4 2.2 1.3e-10 40.8 1.1 2.2 2 1 0 2 2 2 1 DnaJ domain DnaJ PF00226.26 KUM60751.1 - 7.4e-20 70.4 1.2 1.1e-19 69.8 0.8 1.3 1 0 0 1 1 1 1 DnaJ domain Gly-zipper_OmpA PF13436.1 KUM60751.1 - 0.00067 19.3 0.3 0.00067 19.3 0.2 1.7 2 0 0 2 2 2 1 Glycine-zipper containing OmpA-like membrane domain DUF456 PF04306.8 KUM60751.1 - 0.031 14.3 1.6 0.046 13.7 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Bacteriocin_IIc PF10439.4 KUM60751.1 - 0.29 11.2 6.1 0.51 10.4 4.2 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.1 KUM60751.1 - 0.55 9.9 11.0 1.1 8.9 7.6 1.4 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.1 KUM60751.1 - 1.2 8.7 14.3 1.3 8.5 9.0 1.7 1 1 1 2 2 2 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.10 KUM60751.1 - 1.7 8.4 13.5 4.4 7.0 9.3 1.7 1 1 0 1 1 1 0 Glycine zipper 2TM domain PMM PF03332.8 KUM60752.1 - 4.2e-100 333.8 0.2 4.8e-100 333.6 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 KUM60752.1 - 0.0008 19.0 0.0 0.0021 17.6 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 KUM60752.1 - 0.0021 17.2 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 TMPIT-like protein S6PP PF05116.8 KUM60752.1 - 0.0084 15.4 0.0 2 7.6 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase DUF1640 PF07798.6 KUM60753.1 - 2.2e-64 216.7 6.0 2.8e-64 216.3 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) CLAMP PF14769.1 KUM60753.1 - 0.053 13.6 0.2 0.66 10.1 0.1 2.4 2 1 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 PNGaseA PF12222.3 KUM60754.1 - 3.8e-176 586.1 6.2 4.8e-176 585.8 4.3 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Ecm29 PF13001.2 KUM60755.1 - 6.9e-160 532.8 0.0 3.2e-158 527.3 0.0 2.8 3 0 0 3 3 3 1 Proteasome stabiliser HEAT_EZ PF13513.1 KUM60755.1 - 1.6e-06 28.3 11.3 0.043 14.3 0.0 8.3 10 0 0 10 10 10 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KUM60755.1 - 1.9e-05 24.9 0.3 0.025 14.9 0.1 5.1 5 2 2 7 7 7 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 KUM60755.1 - 0.00029 20.6 4.6 7.3 6.9 0.1 7.8 8 0 0 8 8 8 1 HEAT repeat Lant_dehyd_N PF04737.8 KUM60756.1 - 0.055 13.4 0.1 0.087 12.8 0.1 1.4 1 0 0 1 1 1 0 Lantibiotic dehydratase, N terminus FAA_hydrolase PF01557.13 KUM60757.1 - 3.3e-62 209.7 0.0 4.3e-62 209.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family HSP20 PF00011.16 KUM60758.1 - 1.4e-15 56.9 0.0 2.2e-10 40.2 0.0 2.1 1 1 0 2 2 2 2 Hsp20/alpha crystallin family WD40 PF00400.27 KUM60759.1 - 4.2e-21 73.9 9.0 9.6e-09 34.7 0.0 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Rax2 PF12768.2 KUM60759.1 - 0.00071 18.8 0.1 0.0036 16.5 0.0 1.9 2 0 0 2 2 2 1 Cortical protein marker for cell polarity DPPIV_N PF00930.16 KUM60759.1 - 0.095 11.2 0.2 19 3.7 0.0 3.2 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Lipase_3 PF01764.20 KUM60760.1 - 9.4e-29 99.8 0.0 1.5e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KUM60760.1 - 0.0055 16.4 0.0 0.0078 15.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KUM60760.1 - 0.019 14.8 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 KUM60760.1 - 0.028 14.0 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Esterase PF00756.15 KUM60760.1 - 0.035 13.5 0.0 0.051 12.9 0.0 1.1 1 0 0 1 1 1 0 Putative esterase DUF2974 PF11187.3 KUM60760.1 - 0.1 11.9 0.0 0.6 9.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) RRM_5 PF13893.1 KUM60762.1 - 3.3e-09 36.4 0.2 4.8e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KUM60762.1 - 3e-07 29.9 0.1 5.6e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM60762.1 - 0.00011 22.1 0.0 0.00018 21.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 KUM60762.1 - 0.00052 19.6 0.2 0.001 18.6 0.1 1.6 1 1 0 1 1 1 1 Calcipressin Fungal_trans_2 PF11951.3 KUM60763.1 - 4.5e-08 32.1 0.0 4.8e-08 31.9 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.3 KUM60764.1 - 8.7e-07 27.8 2.9 1.3e-06 27.2 2.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain WW PF00397.21 KUM60766.1 - 3.4e-09 36.3 0.3 9.1e-09 35.0 0.2 1.8 1 0 0 1 1 1 1 WW domain PhoD PF09423.5 KUM60766.1 - 0.013 14.0 0.4 0.019 13.5 0.3 1.2 1 0 0 1 1 1 0 PhoD-like phosphatase UCR_Fe-S_N PF10399.4 KUM60766.1 - 2.8 7.1 8.8 7.7 5.7 6.1 1.8 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal PRA1 PF03208.14 KUM60767.1 - 4.9e-41 139.6 1.6 5.5e-41 139.4 1.1 1.0 1 0 0 1 1 1 1 PRA1 family protein PAT1 PF09770.4 KUM60768.1 - 0.63 8.2 23.9 1.6 6.8 16.5 1.5 1 1 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Frag1 PF10277.4 KUM60769.1 - 2.9e-39 134.7 2.4 3.3e-39 134.5 1.7 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF3353 PF11833.3 KUM60769.1 - 0.0066 15.9 2.1 0.0088 15.5 0.5 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3353) Tetraspannin PF00335.15 KUM60769.1 - 2.1 7.5 10.5 3.4 6.8 7.3 1.4 1 0 0 1 1 1 0 Tetraspanin family Glyco_hydro_35 PF01301.14 KUM60770.1 - 3.3e-75 253.3 4.3 4.7e-75 252.9 3.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 KUM60770.1 - 2.2e-58 196.6 4.2 2.2e-58 196.6 2.9 1.8 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 KUM60770.1 - 1.8e-48 163.4 2.3 5.2e-25 87.8 0.8 3.2 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 KUM60770.1 - 1.4e-26 91.6 0.5 4.2e-26 90.1 0.4 1.9 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Y_phosphatase3 PF13350.1 KUM60771.1 - 7.8e-13 48.9 0.2 8.5e-13 48.8 0.1 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF2291 PF10054.4 KUM60771.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2291) PhzC-PhzF PF02567.11 KUM60772.1 - 8.8e-41 139.9 0.0 1e-40 139.7 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.6 KUM60772.1 - 0.018 13.8 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Proline racemase KH_1 PF00013.24 KUM60773.1 - 0.00018 21.0 1.8 0.00038 20.0 1.2 1.5 1 0 0 1 1 1 1 KH domain MDM31_MDM32 PF08118.6 KUM60774.1 - 1.4e-197 657.1 0.5 1.6e-197 656.9 0.3 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Peptidase_M61 PF05299.7 KUM60774.1 - 0.076 13.0 0.1 5.2 7.0 0.1 2.4 2 0 0 2 2 2 0 M61 glycyl aminopeptidase HCNGP PF07818.8 KUM60775.1 - 5e-32 109.8 0.5 8e-32 109.1 0.3 1.3 1 0 0 1 1 1 1 HCNGP-like protein Proteasome PF00227.21 KUM60776.1 - 3.5e-32 111.2 0.7 7.1e-31 106.9 0.5 2.1 1 1 0 1 1 1 1 Proteasome subunit Proteasome PF00227.21 KUM60777.1 - 7.8e-29 100.3 0.0 9.5e-29 100.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Glyco_hydro_4 PF02056.11 KUM60777.1 - 0.016 14.5 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase adh_short PF00106.20 KUM60779.1 - 8.2e-17 61.6 0.2 5.5e-16 58.9 0.2 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM60779.1 - 3.2e-05 23.6 0.2 0.0002 21.0 0.0 2.1 2 1 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KUM60779.1 - 0.00049 19.9 0.0 0.023 14.4 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KUM60779.1 - 0.0097 15.3 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TRI12 PF06609.8 KUM60780.1 - 2.4e-35 121.8 23.5 3.1e-35 121.4 16.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KUM60780.1 - 1.4e-07 30.5 40.4 1.4e-07 30.5 28.0 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.20 KUM60781.1 - 3e-24 85.8 0.1 8.1e-24 84.4 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM60781.1 - 1.8e-11 44.2 0.0 3.4e-11 43.3 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM60781.1 - 1.1e-09 38.1 0.1 3.3e-09 36.6 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KUM60781.1 - 0.00035 20.0 0.0 0.00055 19.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KUM60781.1 - 0.0079 16.2 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding GHMP_kinases_N PF00288.21 KUM60782.1 - 5e-08 32.9 0.2 1.2e-07 31.6 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KUM60782.1 - 0.00047 20.2 0.1 0.0024 18.0 0.0 2.1 2 1 0 2 2 2 1 GHMP kinases C terminal Peptidase_A4 PF01828.12 KUM60783.1 - 3.9e-88 293.9 8.4 4.6e-88 293.7 5.8 1.1 1 0 0 1 1 1 1 Peptidase A4 family Histone_HNS PF00816.16 KUM60784.1 - 0.33 11.4 8.6 4.1 7.9 1.0 2.2 2 0 0 2 2 2 0 H-NS histone family Lipase_chap PF03280.9 KUM60784.1 - 9.4 5.7 9.7 1.7 8.0 1.4 2.1 2 0 0 2 2 2 0 Proteobacterial lipase chaperone protein IspD PF01128.14 KUM60785.1 - 1.6e-57 194.6 0.0 2e-57 194.2 0.0 1.1 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YgbB PF02542.11 KUM60785.1 - 3.9e-55 185.9 0.1 8e-55 184.9 0.0 1.5 1 0 0 1 1 1 1 YgbB family NTP_transf_3 PF12804.2 KUM60785.1 - 7.9e-11 42.2 0.0 1.3e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain LysM PF01476.15 KUM60786.1 - 0.0037 17.1 1.6 0.0055 16.5 0.0 2.1 2 0 0 2 2 2 1 LysM domain ESSS PF10183.4 KUM60787.1 - 0.33 11.3 3.7 1.3 9.4 2.6 2.0 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Rhabdo_glycop PF00974.13 KUM60787.1 - 0.52 8.4 1.3 0.73 8.0 0.9 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Baculo_11_kDa PF06143.6 KUM60788.1 - 8.4 5.8 7.2 0.47 9.8 0.4 2.4 2 1 0 2 2 2 0 Baculovirus 11 kDa family Ank_2 PF12796.2 KUM60789.1 - 4.3e-69 228.8 9.7 1.9e-19 69.7 0.2 6.0 2 2 4 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 KUM60789.1 - 2.3e-55 181.7 24.0 2.7e-07 30.0 0.0 11.1 11 0 0 11 11 11 9 Ankyrin repeat Ank_4 PF13637.1 KUM60789.1 - 3.4e-51 170.7 14.1 4e-12 46.3 0.0 8.9 2 1 6 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM60789.1 - 4.6e-46 150.1 6.7 2.8e-05 23.9 0.0 10.6 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.1 KUM60789.1 - 5.1e-34 115.5 9.6 9e-06 25.7 0.0 8.5 2 2 6 8 8 8 8 Ankyrin repeats (many copies) INTS5_N PF14837.1 KUM60789.1 - 0.036 13.4 0.0 0.073 12.4 0.0 1.4 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus DUF1843 PF08898.5 KUM60789.1 - 0.19 11.7 27.0 1.8 8.6 1.6 7.0 3 3 2 6 6 6 0 Domain of unknown function (DUF1843) Bactofilin PF04519.8 KUM60789.1 - 0.21 11.6 3.5 27 4.8 0.0 4.3 4 2 1 5 5 5 0 Polymer-forming cytoskeletal CDC37_N PF03234.9 KUM60790.1 - 0.38 11.0 1.2 0.54 10.5 0.8 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding CCDC144C PF14915.1 KUM60792.1 - 0.9 8.3 4.9 0.25 10.2 0.5 2.1 2 1 1 3 3 3 0 CCDC144C protein coiled-coil region ABC_tran PF00005.22 KUM60794.1 - 3.3e-52 176.4 0.0 3.3e-28 98.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KUM60794.1 - 2.8e-31 108.9 29.7 1.3e-20 73.9 9.6 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KUM60794.1 - 1.4e-09 37.4 4.1 0.0059 15.8 0.1 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KUM60794.1 - 3.2e-09 37.1 5.5 0.00079 19.4 0.1 4.2 4 1 0 4 4 2 2 AAA domain AAA_16 PF13191.1 KUM60794.1 - 2.6e-08 34.0 0.1 7.6e-05 22.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KUM60794.1 - 6.8e-07 28.7 1.8 0.00029 20.2 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KUM60794.1 - 1.8e-06 27.5 0.2 0.0017 17.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KUM60794.1 - 2.8e-06 27.4 0.4 0.027 14.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 KUM60794.1 - 9.7e-06 24.8 0.3 0.0008 18.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 KUM60794.1 - 1.3e-05 24.7 0.1 0.066 12.7 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.1 KUM60794.1 - 4.6e-05 23.8 2.0 0.036 14.4 0.4 2.3 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 KUM60794.1 - 9.4e-05 21.4 0.1 0.028 13.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.24 KUM60794.1 - 9.4e-05 22.6 0.7 0.062 13.5 0.0 3.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 KUM60794.1 - 0.00015 22.2 0.7 0.29 11.6 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 KUM60794.1 - 0.0005 19.5 1.5 0.089 12.2 0.0 2.6 2 0 0 2 2 2 1 AAA-like domain RNA_helicase PF00910.17 KUM60794.1 - 0.00053 20.1 0.0 0.23 11.6 0.0 2.7 2 0 0 2 2 2 1 RNA helicase MMR_HSR1 PF01926.18 KUM60794.1 - 0.00062 19.7 0.0 0.23 11.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.1 KUM60794.1 - 0.00087 19.1 0.0 0.21 11.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KUM60794.1 - 0.00098 18.8 0.0 0.029 14.0 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase NACHT PF05729.7 KUM60794.1 - 0.0018 17.9 0.1 0.14 11.8 0.0 2.8 3 0 0 3 3 2 1 NACHT domain AAA_30 PF13604.1 KUM60794.1 - 0.0073 15.9 0.6 2.1 7.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 KUM60794.1 - 0.0083 15.2 0.2 3.8 6.5 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.17 KUM60794.1 - 0.01 14.7 0.4 2.4 6.9 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.9 KUM60794.1 - 0.012 15.3 0.5 1 9.1 0.0 2.7 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.13 KUM60794.1 - 0.014 14.9 0.1 1.7 8.1 0.0 2.7 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.1 KUM60794.1 - 0.017 15.9 5.3 0.41 11.4 0.3 3.2 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 KUM60794.1 - 0.021 14.5 1.9 5.3 6.7 0.3 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KUM60794.1 - 0.031 14.5 0.1 3.5 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KUM60794.1 - 0.035 14.0 0.3 0.58 10.0 0.0 2.9 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.10 KUM60794.1 - 0.044 13.4 1.0 5.3 6.7 0.1 2.5 2 0 0 2 2 2 0 NTPase cobW PF02492.14 KUM60794.1 - 0.045 13.1 1.6 3 7.2 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 KUM60794.1 - 0.053 12.9 0.1 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF815 PF05673.8 KUM60794.1 - 0.064 12.1 0.0 1.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 KUM60794.1 - 0.075 12.7 0.2 1.1 9.1 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain SbcCD_C PF13558.1 KUM60794.1 - 0.082 12.8 0.0 12 5.8 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.18 KUM60794.1 - 0.09 12.5 0.2 2 8.1 0.0 2.3 2 0 0 2 2 2 0 Dynamin family Guanylate_kin PF00625.16 KUM60794.1 - 0.098 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase Gtr1_RagA PF04670.7 KUM60794.1 - 0.11 11.6 1.3 1.4 8.0 0.4 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region UPF0079 PF02367.12 KUM60794.1 - 0.11 12.1 0.7 8 6.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF3154 PF11351.3 KUM60794.1 - 0.12 12.1 1.1 0.5 10.1 0.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) PIF1 PF05970.9 KUM60794.1 - 0.13 11.1 0.0 0.56 9.0 0.0 1.9 2 0 0 2 2 2 0 PIF1-like helicase Pox_A32 PF04665.7 KUM60794.1 - 0.14 11.4 0.4 7.8 5.7 0.1 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein IstB_IS21 PF01695.12 KUM60794.1 - 0.16 11.3 2.1 5.2 6.4 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein PduV-EutP PF10662.4 KUM60794.1 - 0.17 11.4 1.3 2 7.9 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.1 KUM60794.1 - 0.24 10.4 0.0 0.56 9.1 0.0 1.5 2 0 0 2 2 1 0 AAA ATPase domain DUF87 PF01935.12 KUM60794.1 - 0.5 10.1 1.8 3.8 7.2 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 ABC_ATPase PF09818.4 KUM60794.1 - 1.4 7.4 6.9 0.2 10.2 0.2 2.7 4 0 0 4 4 4 0 Predicted ATPase of the ABC class Nup160 PF11715.3 KUM60795.1 - 2.6e-157 524.2 1.0 4.4e-157 523.5 0.7 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Rad51 PF08423.6 KUM60796.1 - 3.8e-138 458.5 0.0 4.6e-138 458.2 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KUM60796.1 - 4e-14 52.4 0.0 5.5e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 KUM60796.1 - 1.1e-08 35.0 0.4 4.1e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain RecA PF00154.16 KUM60796.1 - 2.2e-08 33.5 0.0 3.1e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 KUM60796.1 - 2.6e-05 23.4 0.2 7.3e-05 21.9 0.1 1.8 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.10 KUM60796.1 - 0.024 13.5 0.0 0.039 12.8 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 KUM60796.1 - 0.077 11.8 0.2 0.22 10.3 0.1 1.7 2 0 0 2 2 2 0 PAXNEB protein Catalase PF00199.14 KUM60798.1 - 1.9e-169 563.4 0.1 2.4e-169 563.0 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KUM60798.1 - 2.3e-13 49.8 0.3 6e-13 48.4 0.1 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive Mito_carr PF00153.22 KUM60800.1 - 1.8e-70 232.7 1.0 1.5e-23 82.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Chromate_transp PF02417.10 KUM60800.1 - 0.018 14.6 0.8 0.54 9.8 0.0 2.4 2 0 0 2 2 2 0 Chromate transporter HMD PF03201.11 KUM60800.1 - 0.057 13.3 0.0 1.8 8.5 0.0 2.5 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase adh_short PF00106.20 KUM60801.1 - 5.6e-11 42.6 0.1 6.5e-11 42.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM60801.1 - 1.1e-05 25.1 0.1 1.4e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KUM60801.1 - 0.00056 19.7 0.0 0.00088 19.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KUM60801.1 - 0.0099 15.3 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KUM60801.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Ribonuc_L-PSP PF01042.16 KUM60804.1 - 9.6e-37 125.4 0.0 1.1e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP AFG1_ATPase PF03969.11 KUM60805.1 - 1e-95 320.6 0.0 2.2e-90 303.0 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 KUM60805.1 - 0.0019 18.2 0.1 0.31 11.0 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain Bac_DnaA PF00308.13 KUM60805.1 - 0.0029 17.2 0.4 0.64 9.6 0.1 2.4 2 1 0 2 2 2 2 Bacterial dnaA protein AAA_22 PF13401.1 KUM60805.1 - 0.0047 17.0 0.0 0.015 15.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KUM60805.1 - 0.0094 16.1 0.0 0.041 14.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KUM60805.1 - 0.011 15.8 0.0 0.078 13.1 0.0 2.4 3 0 0 3 3 3 0 RNA helicase SH3_1 PF00018.23 KUM60806.1 - 1.5e-25 88.3 0.0 2.2e-11 42.9 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 KUM60806.1 - 9.8e-16 57.0 0.1 2e-07 30.4 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 KUM60806.1 - 5.4e-14 51.9 0.0 1.1e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 KUM60806.1 - 1.9e-09 36.8 0.0 2e-05 23.9 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.19 KUM60806.1 - 5.3e-08 32.4 0.5 1.1e-07 31.3 0.3 1.6 1 0 0 1 1 1 1 PB1 domain SAC3_GANP PF03399.11 KUM60807.1 - 7.4e-66 221.5 0.1 9.8e-66 221.2 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KUM60807.1 - 0.0004 20.1 0.0 0.00086 19.0 0.0 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 EAP30 PF04157.11 KUM60808.1 - 5e-53 179.5 0.0 6.9e-53 179.0 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 KUM60808.1 - 7.6e-27 92.9 0.0 1.3e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 KUM60808.1 - 7.2e-05 22.2 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 GRAM domain zf-RanBP PF00641.13 KUM60808.1 - 0.00012 21.0 13.0 0.00063 18.7 0.8 2.7 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 KUM60808.1 - 0.00081 18.8 4.7 0.011 15.2 0.5 2.5 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger DZR PF12773.2 KUM60808.1 - 0.47 10.3 5.9 0.22 11.3 0.4 2.4 2 1 0 2 2 2 0 Double zinc ribbon Fungal_trans PF04082.13 KUM60809.1 - 1.7e-08 33.6 1.3 1.7e-08 33.6 0.9 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain BsuPI PF12690.2 KUM60809.1 - 0.1 12.3 0.1 0.61 9.8 0.0 2.1 2 0 0 2 2 2 0 Intracellular proteinase inhibitor Bac_rhamnosid_N PF08531.5 KUM60810.1 - 1e-05 25.1 0.0 1.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Catalase PF00199.14 KUM60813.1 - 1.7e-158 527.2 0.0 2.2e-158 526.9 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KUM60813.1 - 4.6e-19 68.0 0.0 1.3e-18 66.6 0.0 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive DUF4066 PF13278.1 KUM60813.1 - 0.00011 21.5 0.0 0.00024 20.3 0.0 1.6 2 0 0 2 2 2 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KUM60813.1 - 0.00026 20.4 0.0 0.00054 19.4 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Cation_efflux PF01545.16 KUM60814.1 - 6.1e-72 242.0 5.1 7.1e-72 241.8 3.5 1.0 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 KUM60814.1 - 2.2e-06 26.9 9.3 3.3e-06 26.3 6.5 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter BPD_transp_2 PF02653.11 KUM60814.1 - 0.01 14.8 1.4 0.01 14.8 1.0 1.9 2 1 0 2 2 2 0 Branched-chain amino acid transport system / permease component Propep_M14 PF02244.11 KUM60814.1 - 0.078 12.6 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Amidase PF01425.16 KUM60815.1 - 6.2e-95 318.6 0.0 7.3e-95 318.4 0.0 1.0 1 0 0 1 1 1 1 Amidase Methyltransf_11 PF08241.7 KUM60816.1 - 7.4e-10 39.1 0.0 1.2e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM60816.1 - 1.9e-06 27.6 0.0 2.8e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM60816.1 - 3.1e-06 27.5 0.0 4.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM60816.1 - 7.3e-06 26.5 0.0 1.5e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM60816.1 - 0.00012 22.3 0.0 0.0002 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KUM60816.1 - 0.00041 19.8 0.0 0.00066 19.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 KUM60816.1 - 0.001 18.6 0.0 0.002 17.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 KUM60816.1 - 0.039 13.2 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase MTS PF05175.9 KUM60816.1 - 0.16 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Acetyltransf_3 PF13302.1 KUM60817.1 - 6.9e-14 52.2 0.0 9.3e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KUM60817.1 - 6.4e-06 26.2 0.0 8.4e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KUM60817.1 - 1.7e-05 24.7 0.0 2.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KUM60817.1 - 0.0039 17.0 0.0 0.0058 16.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 KUM60818.1 - 7.5e-28 97.2 61.2 1.4e-23 83.1 29.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Chitin_synth_1 PF01644.12 KUM60819.1 - 2.5e-85 284.2 0.1 4e-85 283.5 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KUM60819.1 - 3.6e-31 106.6 0.2 7e-31 105.7 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KUM60819.1 - 5.2e-22 77.9 1.7 7.4e-20 70.8 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KUM60819.1 - 8.1e-09 35.4 0.3 8.1e-09 35.4 0.2 2.3 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KUM60819.1 - 5.7e-06 26.2 0.0 1.1e-05 25.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 DUF1774 PF08611.5 KUM60820.1 - 1.4e-36 124.5 4.4 1.4e-36 124.5 3.0 2.1 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1774) Inositol_P PF00459.20 KUM60821.1 - 6.7e-40 137.0 0.1 1.2e-39 136.2 0.0 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family Peptidase_M28 PF04389.12 KUM60822.1 - 2.8e-26 92.3 0.0 5.1e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KUM60822.1 - 2.1e-07 30.6 0.0 3.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 R3H-assoc PF13902.1 KUM60823.1 - 3.4e-28 98.2 4.5 6.3e-28 97.3 3.1 1.5 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.17 KUM60823.1 - 0.0031 17.1 0.1 0.011 15.4 0.1 2.0 1 0 0 1 1 1 1 R3H domain dsrm PF00035.20 KUM60825.1 - 0.003 18.0 0.0 0.0073 16.8 0.0 1.6 1 1 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KUM60825.1 - 0.0084 16.3 0.1 0.036 14.3 0.1 1.9 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 WxL PF13731.1 KUM60825.1 - 0.065 13.0 1.8 1.6 8.4 0.1 2.0 1 1 1 2 2 2 0 WxL domain surface cell wall-binding Sugar_tr PF00083.19 KUM60827.1 - 2e-45 155.2 12.0 2.3e-45 155.0 8.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM60827.1 - 0.0042 15.8 11.3 0.0042 15.8 7.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily bZIP_1 PF00170.16 KUM60828.1 - 2.3e-10 40.2 12.5 5.6e-10 39.0 8.7 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KUM60828.1 - 3.1e-06 26.9 10.9 3.1e-06 26.9 7.6 1.8 2 0 0 2 2 2 1 Basic region leucine zipper Rb_C PF08934.5 KUM60828.1 - 0.023 14.3 0.1 0.063 12.9 0.0 1.8 1 0 0 1 1 1 0 Rb C-terminal domain bZIP_Maf PF03131.12 KUM60828.1 - 0.27 11.5 10.7 0.16 12.2 5.9 1.7 1 1 0 1 1 1 0 bZIP Maf transcription factor Mnd1 PF03962.10 KUM60828.1 - 1 9.0 5.6 1.5 8.4 3.9 1.3 1 0 0 1 1 1 0 Mnd1 family Kinesin PF00225.18 KUM60830.1 - 2.2e-112 375.0 0.0 3.4e-112 374.4 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain RhgB_N PF09284.5 KUM60830.1 - 0.033 13.5 0.0 0.065 12.5 0.0 1.4 1 0 0 1 1 1 0 Rhamnogalacturonase B, N-terminal DUF1460 PF07313.7 KUM60830.1 - 0.17 11.0 3.6 0.11 11.7 1.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1460) V_ATPase_I PF01496.14 KUM60830.1 - 0.58 7.9 6.4 0.96 7.2 4.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.7 KUM60830.1 - 3.1 7.5 16.1 0.79 9.4 8.8 1.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Caudo_TAP PF02413.12 KUM60830.1 - 8.1 6.6 9.8 9.3 6.4 4.1 2.7 3 0 0 3 3 3 0 Caudovirales tail fibre assembly protein adh_short PF00106.20 KUM60831.1 - 2.1e-16 60.3 0.0 2.7e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM60831.1 - 2.2e-08 34.1 0.0 2.8e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KUM60831.1 - 0.0005 20.1 0.0 0.00078 19.5 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KUM60831.1 - 0.0022 17.6 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM60831.1 - 0.0058 16.1 0.0 0.0074 15.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1275 PF06912.6 KUM60833.1 - 2.4e-45 154.3 10.8 2.9e-45 154.0 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) UPF0154 PF03672.8 KUM60833.1 - 0.15 11.7 0.7 0.28 10.8 0.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) DUF3953 PF13129.1 KUM60833.1 - 1.7 8.3 0.0 1.7 8.3 0.0 3.5 4 1 1 5 5 5 0 Protein of unknown function (DUF3953) PrgI PF12666.2 KUM60833.1 - 2.4 8.3 5.8 2.7 8.2 0.1 3.0 2 1 0 3 3 3 0 PrgI family protein Ank_2 PF12796.2 KUM60834.1 - 4.6e-30 103.7 0.0 8e-12 45.3 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KUM60834.1 - 2.3e-17 61.8 0.3 0.0015 18.2 0.0 5.7 5 1 1 6 6 6 4 Ankyrin repeat Ank_3 PF13606.1 KUM60834.1 - 9.6e-13 47.0 0.1 0.0029 17.7 0.0 5.2 3 1 2 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KUM60834.1 - 7.9e-09 35.4 0.2 0.13 12.5 0.0 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KUM60834.1 - 1e-07 32.2 0.0 0.048 14.1 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ion_trans_2 PF07885.11 KUM60835.1 - 1.3e-27 95.3 19.6 1.1e-16 60.3 3.7 3.7 4 0 0 4 4 4 2 Ion channel GXWXG PF14231.1 KUM60836.1 - 5e-19 67.6 0.2 2.2e-18 65.6 0.0 1.9 2 0 0 2 2 2 1 GXWXG protein DUF4334 PF14232.1 KUM60836.1 - 3.1e-14 52.3 0.0 4.6e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4334) Fungal_trans_2 PF11951.3 KUM60837.1 - 1.8e-50 171.6 0.0 3.6e-50 170.6 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM60837.1 - 1.9e-05 24.4 5.9 4.1e-05 23.4 4.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BCIP PF13862.1 KUM60840.1 - 2.6e-74 248.9 0.2 3.3e-74 248.6 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Sad1_UNC PF07738.8 KUM60841.1 - 2.5e-10 40.2 0.3 5.7e-07 29.4 0.0 2.6 3 0 0 3 3 3 2 Sad1 / UNC-like C-terminal CBS PF00571.23 KUM60842.1 - 5.2e-25 86.9 4.2 2.9e-11 42.9 0.0 4.1 4 0 0 4 4 4 3 CBS domain RhoGAP PF00620.22 KUM60843.1 - 2.7e-05 23.8 0.0 4.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Mannosyl_trans3 PF11051.3 KUM60844.1 - 1.3e-76 257.5 0.0 3.6e-76 256.0 0.0 1.7 1 1 0 1 1 1 1 Mannosyltransferase putative ANAPC15 PF15243.1 KUM60844.1 - 0.026 14.5 0.0 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 DUF3177 PF11375.3 KUM60846.1 - 0.062 12.7 0.1 0.096 12.1 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3177) NAD_binding_6 PF08030.7 KUM60847.1 - 4.7e-26 91.5 0.0 6e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KUM60847.1 - 1.4e-11 44.2 0.0 3.3e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 KUM60847.1 - 0.021 15.3 0.0 0.27 11.8 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Apc13p PF05839.6 KUM60848.1 - 2.4e-19 69.1 0.1 1.2e-14 54.0 0.0 2.3 2 0 0 2 2 2 2 Apc13p protein ydhR PF08803.6 KUM60848.1 - 0.1 12.7 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative mono-oxygenase ydhR IF-2B PF01008.12 KUM60849.1 - 5.8e-75 251.8 0.0 7.4e-75 251.5 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family CRAL_TRIO PF00650.15 KUM60850.1 - 4.5e-39 133.4 0.0 6.3e-39 133.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KUM60850.1 - 1.6e-12 47.3 0.2 4.4e-12 45.9 0.1 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KUM60850.1 - 3.3e-06 27.0 0.0 4.8e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Mec-17 PF05301.6 KUM60850.1 - 0.014 15.3 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Touch receptor neuron protein Mec-17 HrpB_C PF08482.5 KUM60850.1 - 0.015 15.4 0.1 0.11 12.5 0.0 2.2 1 1 1 2 2 2 0 ATP-dependent helicase C-terminal Pol_alpha_B_N PF08418.5 KUM60851.1 - 1.1e-60 205.3 0.0 1.4e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 KUM60851.1 - 2.3e-36 125.0 0.0 3.3e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CM_2 PF01817.16 KUM60852.1 - 2.9e-10 40.1 0.0 3.2e-07 30.3 0.0 2.9 2 1 0 2 2 2 2 Chorismate mutase type II WD40 PF00400.27 KUM60853.1 - 7.1e-38 127.1 7.4 1.3e-09 37.5 0.6 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 KUM60853.1 - 1.2e-05 23.7 7.9 0.049 11.7 0.2 4.3 1 1 4 5 5 5 3 Nucleoporin Nup120/160 APG6 PF04111.7 KUM60853.1 - 0.0054 15.8 0.3 0.0089 15.1 0.2 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 KUM60853.1 - 0.071 13.1 1.1 0.12 12.4 0.2 1.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 KUM60853.1 - 0.13 11.8 1.7 0.26 10.8 1.2 1.5 1 0 0 1 1 1 0 IncA protein DUF1664 PF07889.7 KUM60853.1 - 0.24 11.1 0.7 2.2 8.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SRR1 PF07985.7 KUM60854.1 - 0.0019 18.0 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 SRR1 SnoaL PF07366.7 KUM60856.1 - 3e-30 104.4 0.0 3.3e-30 104.2 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KUM60856.1 - 4.1e-16 59.2 0.0 4.6e-16 59.0 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain Aldo_ket_red PF00248.16 KUM60857.1 - 1.7e-48 164.9 0.0 2e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_S17e PF00833.13 KUM60858.1 - 3.4e-59 197.9 0.7 4.2e-59 197.6 0.5 1.1 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 KUM60858.1 - 0.051 14.2 0.1 0.08 13.6 0.1 1.4 1 1 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal Mit_ribos_Mrp51 PF11709.3 KUM60859.1 - 5.4e-98 328.0 0.1 6.4e-98 327.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Epimerase PF01370.16 KUM60860.1 - 1.7e-18 66.9 0.0 2.2e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KUM60860.1 - 1.3e-16 60.1 0.0 1.6e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KUM60860.1 - 6.6e-10 38.3 0.0 1.9e-09 36.8 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KUM60860.1 - 7.5e-09 35.8 0.0 1.3e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KUM60860.1 - 3e-06 27.2 0.0 5.2e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KUM60860.1 - 0.00011 21.2 0.0 0.00017 20.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 KUM60860.1 - 0.00011 21.5 0.4 0.0017 17.6 0.2 2.3 2 1 0 2 2 2 1 NmrA-like family KR PF08659.5 KUM60860.1 - 0.00026 20.6 0.0 0.00065 19.4 0.0 1.6 2 0 0 2 2 2 1 KR domain Saccharop_dh PF03435.13 KUM60860.1 - 0.00033 19.7 0.2 0.0019 17.2 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KUM60860.1 - 0.037 14.3 0.0 0.098 12.9 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short_C2 PF13561.1 KUM60860.1 - 0.041 13.6 0.1 0.089 12.5 0.0 1.6 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase F-box-like PF12937.2 KUM60861.1 - 2.4e-05 23.9 0.1 5.9e-05 22.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like FAT PF02259.18 KUM60862.1 - 8.5e-127 422.9 0.4 8.5e-127 422.9 0.3 1.9 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.3 KUM60862.1 - 6.1e-61 205.0 1.0 1.2e-57 194.2 0.6 3.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 KUM60862.1 - 3.7e-58 196.7 0.2 9e-58 195.5 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 KUM60862.1 - 4e-40 135.9 0.1 4e-40 135.9 0.1 3.5 3 1 1 4 4 4 1 Rapamycin binding domain HEAT_2 PF13646.1 KUM60862.1 - 1.4e-17 63.6 8.8 0.0028 17.9 0.0 9.0 7 2 2 9 9 9 6 HEAT repeats FATC PF02260.15 KUM60862.1 - 2.7e-16 58.6 0.7 6.4e-16 57.4 0.5 1.7 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.1 KUM60862.1 - 4.2e-15 55.7 6.9 0.0032 17.8 0.0 11.1 10 2 4 14 14 14 3 HEAT-like repeat HEAT PF02985.17 KUM60862.1 - 2.1e-11 42.8 17.4 0.16 12.1 0.0 11.2 12 0 0 12 12 12 3 HEAT repeat CLASP_N PF12348.3 KUM60862.1 - 0.00086 18.7 1.5 0.94 8.7 0.0 4.8 6 0 0 6 6 6 1 CLASP N terminal CWC25 PF12542.3 KUM60863.1 - 1.6e-22 79.7 0.0 1.6e-22 79.7 0.0 3.9 4 1 1 5 5 5 1 Pre-mRNA splicing factor Cir_N PF10197.4 KUM60863.1 - 1.9e-14 53.4 9.6 1.9e-14 53.4 6.6 4.9 4 1 1 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF4246 PF14033.1 KUM60865.1 - 5.6e-29 101.1 0.2 7.4e-29 100.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) RPAP2_Rtr1 PF04181.8 KUM60866.1 - 1.1e-14 54.2 0.0 2.4e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Rtr1/RPAP2 family Milton PF12448.3 KUM60866.1 - 0.064 13.4 0.2 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 Kinesin associated protein ECH PF00378.15 KUM60868.1 - 5.2e-49 166.5 0.0 6.5e-49 166.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DoxD PF04173.8 KUM60868.1 - 0.035 13.7 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 TQO small subunit DoxD MFS_1 PF07690.11 KUM60869.1 - 8.4e-22 77.3 44.1 8.4e-22 77.3 30.6 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily ABC_membrane PF00664.18 KUM60870.1 - 1.2e-76 257.8 28.6 4.1e-46 157.5 4.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KUM60870.1 - 1.6e-62 209.8 0.1 7.1e-31 107.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KUM60870.1 - 1.1e-16 60.7 0.6 9.2e-06 25.0 0.0 4.4 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KUM60870.1 - 2.5e-09 36.5 0.2 0.0012 18.3 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 KUM60870.1 - 5.4e-09 36.4 0.0 0.033 14.1 0.0 4.3 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 KUM60870.1 - 3.9e-08 33.4 2.2 0.0029 17.5 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 KUM60870.1 - 2.7e-07 31.4 0.0 0.041 14.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KUM60870.1 - 9.3e-07 29.0 2.0 0.62 10.1 0.0 4.4 3 1 0 3 3 3 2 AAA domain DUF258 PF03193.11 KUM60870.1 - 2.7e-06 26.6 0.0 0.019 14.1 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 KUM60870.1 - 5.6e-06 25.2 1.9 0.0019 16.8 0.0 2.8 4 0 0 4 4 4 2 Predicted ATPase of the ABC class DUF87 PF01935.12 KUM60870.1 - 1.1e-05 25.4 0.4 0.023 14.4 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_30 PF13604.1 KUM60870.1 - 1.3e-05 24.8 0.8 0.34 10.4 0.0 4.3 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.1 KUM60870.1 - 1.6e-05 24.3 0.6 0.38 10.1 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.1 KUM60870.1 - 2.3e-05 24.7 0.2 0.21 11.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain APS_kinase PF01583.15 KUM60870.1 - 2.4e-05 24.0 1.4 0.0051 16.4 0.0 2.7 3 0 0 3 3 2 1 Adenylylsulphate kinase AAA_19 PF13245.1 KUM60870.1 - 0.0001 22.0 0.2 0.3 10.8 0.0 3.3 2 0 0 2 2 2 2 Part of AAA domain AAA PF00004.24 KUM60870.1 - 0.00037 20.6 0.6 7 6.8 0.1 4.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KUM60870.1 - 0.0006 19.7 0.2 1.7 8.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KUM60870.1 - 0.00062 18.9 1.1 0.12 11.4 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin AAA_18 PF13238.1 KUM60870.1 - 0.0008 19.7 0.8 1.5 9.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.9 KUM60870.1 - 0.00094 18.9 0.0 2.2 7.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 KUM60870.1 - 0.0012 18.7 0.2 3.1 7.7 0.0 3.3 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 KUM60870.1 - 0.0021 17.9 0.0 3.7 7.4 0.0 3.3 3 1 0 4 4 2 1 AAA domain AAA_10 PF12846.2 KUM60870.1 - 0.0027 17.1 4.4 0.29 10.5 0.1 3.6 2 1 0 3 3 3 1 AAA-like domain FtsK_SpoIIIE PF01580.13 KUM60870.1 - 0.007 15.8 0.0 0.15 11.5 0.0 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family MobB PF03205.9 KUM60870.1 - 0.023 14.4 0.2 9.4 5.9 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KUM60870.1 - 0.024 14.5 1.0 4.3 7.3 0.0 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase DUF3987 PF13148.1 KUM60870.1 - 0.07 11.6 0.0 8.4 4.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) NB-ARC PF00931.17 KUM60870.1 - 0.17 10.7 0.3 12 4.6 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Acetyltransf_8 PF13523.1 KUM60871.1 - 9e-34 116.5 0.3 1.3e-33 115.9 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1749 PF08538.5 KUM60872.1 - 2.8e-97 325.2 0.0 3.1e-97 325.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 KUM60872.1 - 2e-07 31.1 0.0 3.1e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM60872.1 - 4.7e-07 29.6 0.1 1.4e-06 28.1 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KUM60872.1 - 0.0036 16.9 0.1 0.058 12.9 0.0 2.6 1 1 1 2 2 2 1 PGAP1-like protein DUF900 PF05990.7 KUM60872.1 - 0.006 15.9 0.0 0.019 14.3 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.15 KUM60872.1 - 0.067 12.7 0.6 0.23 10.9 0.3 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold AMP-binding PF00501.23 KUM60873.1 - 3.5e-83 279.3 0.0 2e-77 260.3 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KUM60873.1 - 2e-68 230.4 0.1 3.1e-34 118.1 0.0 2.6 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KUM60873.1 - 1.4e-26 92.5 0.2 2.3e-12 46.9 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KUM60873.1 - 4.1e-08 34.0 0.1 0.0035 18.2 0.0 2.9 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain AATase PF07247.7 KUM60873.1 - 0.43 9.0 0.3 5 5.5 0.0 2.3 2 1 0 2 2 2 0 Alcohol acetyltransferase SH3_9 PF14604.1 KUM60874.1 - 1.6e-08 33.9 0.3 3.5e-08 32.9 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KUM60874.1 - 7.3e-07 28.4 0.1 1.5e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KUM60874.1 - 1.3e-05 24.6 0.0 2.5e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain FAA_hydrolase PF01557.13 KUM60877.1 - 7e-58 195.6 0.0 9.8e-58 195.1 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Pkinase PF00069.20 KUM60880.1 - 2.8e-64 216.7 0.0 4.2e-64 216.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM60880.1 - 5.9e-27 94.3 0.0 1.1e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM60880.1 - 0.067 12.1 0.0 0.14 11.0 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Sod_Cu PF00080.15 KUM60881.1 - 1.2e-13 51.4 0.0 1.6e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 KUM60881.1 - 1.1e-12 47.8 0.0 2.4e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain AMP-binding PF00501.23 KUM60883.1 - 3.3e-79 266.2 0.0 4.9e-79 265.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KUM60883.1 - 0.014 16.3 0.0 0.038 14.9 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain AAA_30 PF13604.1 KUM60883.1 - 0.014 15.0 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain CdhD PF03599.11 KUM60883.1 - 0.1 11.0 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit NDT80_PhoG PF05224.7 KUM60885.1 - 9.6e-37 126.7 0.0 1.7e-36 125.9 0.0 1.4 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family HSP70 PF00012.15 KUM60886.1 - 1.3e-261 868.8 18.8 1.5e-261 868.6 13.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KUM60886.1 - 1.4e-14 53.4 6.1 1.7e-13 49.9 1.8 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 KUM60886.1 - 0.0021 17.7 0.2 0.0062 16.1 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 KUM60886.1 - 0.006 16.4 10.4 2.2 8.1 3.3 4.6 2 2 0 2 2 2 1 Cell division protein FtsA DUF1273 PF06908.6 KUM60886.1 - 0.018 14.7 1.2 0.053 13.1 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) IncA PF04156.9 KUM60886.1 - 6.7 6.2 12.2 13 5.3 8.5 1.4 1 0 0 1 1 1 0 IncA protein Methyltransf_16 PF10294.4 KUM60887.1 - 8.1e-07 28.6 0.0 0.02 14.3 0.0 2.8 1 1 1 3 3 3 2 Putative methyltransferase DUF1682 PF07946.9 KUM60888.1 - 5.7 5.6 6.7 8.5 5.1 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) zf-H2C2_2 PF13465.1 KUM60889.1 - 1.6e-07 31.2 3.6 1.6e-07 31.2 2.5 3.2 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.21 KUM60889.1 - 1.6e-05 24.9 16.4 0.00025 21.1 2.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KUM60889.1 - 2e-05 24.3 0.7 4.6e-05 23.1 0.5 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KUM60889.1 - 0.00068 19.7 17.6 0.0065 16.7 1.9 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 KUM60889.1 - 0.027 14.6 1.4 0.027 14.6 0.9 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KUM60889.1 - 0.035 14.2 0.4 0.035 14.2 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FAD_binding_3 PF01494.14 KUM60890.1 - 1.1e-34 120.0 0.0 1.2e-19 70.6 0.0 2.1 1 1 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 KUM60890.1 - 0.05 12.6 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 KUM60890.1 - 0.07 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Glyco_hydro_7 PF00840.15 KUM60890.1 - 0.11 10.8 0.0 0.15 10.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 7 Glyoxalase PF00903.20 KUM60891.1 - 0.08 12.9 0.1 0.094 12.6 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.20 KUM60892.1 - 3.5e-07 30.2 2.2 6.9e-07 29.2 1.5 1.5 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KUM60892.1 - 0.015 15.8 0.1 0.03 14.9 0.1 1.5 1 0 0 1 1 1 0 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KUM60892.1 - 0.063 13.3 0.2 0.13 12.2 0.2 1.6 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily adh_short PF00106.20 KUM60894.1 - 5.1e-18 65.5 0.0 8.2e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM60894.1 - 6.2e-11 42.2 0.0 1.3e-10 41.2 0.0 1.5 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 KUM60894.1 - 9.1e-05 22.5 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 KUM60894.1 - 0.00094 18.1 0.0 0.0012 17.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KUM60894.1 - 0.0015 17.9 0.0 0.0033 16.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KUM60894.1 - 0.0016 18.2 0.0 0.0039 16.9 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KUM60894.1 - 0.0021 18.0 0.0 0.0053 16.7 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding DXP_reductoisom PF02670.11 KUM60894.1 - 0.035 14.6 0.1 0.061 13.8 0.1 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NAD_binding_4 PF07993.7 KUM60894.1 - 0.13 11.1 0.0 0.34 9.7 0.0 1.6 2 0 0 2 2 2 0 Male sterility protein Transp_cyt_pur PF02133.10 KUM60895.1 - 7e-44 150.0 38.3 8.6e-44 149.7 26.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.11 KUM60896.1 - 5.1e-12 45.1 14.4 5.1e-12 45.1 10.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily eIF3g PF12353.3 KUM60897.1 - 8e-46 155.1 2.3 1.1e-45 154.6 1.6 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 KUM60897.1 - 1.1e-14 53.8 0.0 1.9e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM60897.1 - 3.9e-11 42.7 0.0 9.6e-11 41.5 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM60897.1 - 1.6e-06 27.8 0.0 2.9e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_2 PF12796.2 KUM60898.1 - 4.3e-59 196.8 12.7 3.6e-15 56.0 0.1 8.0 2 2 9 11 11 11 10 Ankyrin repeats (3 copies) Ank PF00023.25 KUM60898.1 - 1.1e-31 107.0 17.7 0.00031 20.4 0.0 13.7 14 0 0 14 14 14 8 Ankyrin repeat Ank_3 PF13606.1 KUM60898.1 - 6.4e-30 100.2 11.0 0.0073 16.4 0.0 13.7 15 0 0 15 15 15 7 Ankyrin repeat Ank_4 PF13637.1 KUM60898.1 - 4.2e-29 100.3 8.6 1.1e-07 32.1 0.1 10.0 6 3 4 10 10 10 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM60898.1 - 2e-19 69.1 13.5 0.25 11.6 0.0 10.7 10 3 2 12 12 12 6 Ankyrin repeats (many copies) Clr5 PF14420.1 KUM60898.1 - 1.8e-15 56.5 0.1 3.5e-15 55.6 0.1 1.5 1 0 0 1 1 1 1 Clr5 domain DUF3447 PF11929.3 KUM60898.1 - 0.0077 16.0 1.7 45 3.9 0.0 4.8 5 1 0 5 5 5 0 Domain of unknown function (DUF3447) ADH_N PF08240.7 KUM60899.1 - 1.7e-16 59.8 0.6 1.7e-16 59.8 0.4 2.3 3 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM60899.1 - 2.6e-08 33.4 0.0 3.4e-07 29.8 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase HI0933_like PF03486.9 KUM60899.1 - 0.16 10.4 0.1 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein adh_short PF00106.20 KUM60900.1 - 4.2e-15 56.0 0.1 7.3e-15 55.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM60900.1 - 0.00023 20.8 0.1 0.00044 19.9 0.1 1.4 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KUM60900.1 - 0.0017 18.1 0.0 0.0022 17.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PDEase_I PF00233.14 KUM60901.1 - 1.5e-48 165.6 0.0 2.4e-47 161.6 0.0 2.1 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase G-gamma PF00631.17 KUM60902.1 - 5.8e-25 86.8 0.0 6.7e-25 86.6 0.0 1.1 1 0 0 1 1 1 1 GGL domain RSS_P20 PF11757.3 KUM60902.1 - 0.11 12.6 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like PCI PF01399.22 KUM60904.1 - 1.6e-09 38.0 3.7 3.8e-09 36.7 0.0 3.2 3 0 0 3 3 3 1 PCI domain ADH_zinc_N PF00107.21 KUM60905.1 - 1.3e-22 79.7 0.0 2.2e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KUM60905.1 - 2.3e-13 51.1 0.0 5.1e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM60905.1 - 1.2e-10 41.0 0.0 4.8e-09 35.9 0.0 2.2 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain zf-HC5HC2H_2 PF13832.1 KUM60906.1 - 7.1e-22 77.4 0.2 7.1e-22 77.4 0.2 4.2 4 0 0 4 4 4 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KUM60906.1 - 9.6e-22 76.9 0.8 9.6e-22 76.9 0.5 4.4 4 0 0 4 4 4 2 PHD-like zinc-binding domain BAH PF01426.13 KUM60906.1 - 9.5e-14 51.1 0.0 2e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 KUM60906.1 - 6.8e-12 44.8 47.9 2.2e-07 30.4 5.2 5.1 5 0 0 5 5 5 3 PHD-finger PHD_2 PF13831.1 KUM60906.1 - 7.8e-09 34.7 4.5 7.8e-09 34.7 3.1 5.0 6 0 0 6 6 6 2 PHD-finger Myb_DNA-binding PF00249.26 KUM60906.1 - 1.1e-05 25.3 0.4 6.2e-05 22.9 0.1 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain GATA PF00320.22 KUM60906.1 - 4.2 6.8 15.4 1.5 8.2 0.7 4.7 4 0 0 4 4 4 0 GATA zinc finger Peptidase_M35 PF02102.10 KUM60907.1 - 2e-29 102.3 6.3 2.4e-29 102.1 4.4 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 KUM60907.1 - 1.8e-05 25.2 0.3 2.5e-05 24.8 0.2 1.2 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase DUF630 PF04783.7 KUM60907.1 - 0.091 12.6 0.4 0.17 11.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF630) NanE PF04131.9 KUM60908.1 - 0.11 11.4 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase 2Fe-2S_thioredx PF01257.14 KUM60909.1 - 6.8e-59 197.6 0.0 9.5e-59 197.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF221 PF02714.10 KUM60910.1 - 6.7e-111 370.2 28.4 6.7e-111 370.2 19.7 1.7 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KUM60910.1 - 1.6e-46 157.7 0.6 1.6e-46 157.7 0.4 3.4 3 1 1 4 4 4 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KUM60910.1 - 3e-14 52.6 0.0 7.4e-14 51.4 0.0 1.7 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KUM60910.1 - 5.7e-12 45.9 4.4 4.2e-05 23.9 1.2 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4463) GP41 PF00517.12 KUM60910.1 - 0.031 13.8 0.7 0.75 9.3 0.4 2.8 2 1 0 2 2 2 0 Retroviral envelope protein PT-TG PF14449.1 KUM60910.1 - 0.064 13.0 0.7 0.77 9.5 0.2 2.7 2 0 0 2 2 2 0 Pre-toxin TG MCM PF00493.18 KUM60911.1 - 8.4e-140 465.2 0.0 1.2e-139 464.8 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KUM60911.1 - 1.1e-20 74.3 0.0 6e-20 71.9 0.0 2.3 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 KUM60911.1 - 6.8e-06 25.3 0.0 0.0002 20.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KUM60911.1 - 1.5e-05 24.7 0.0 3.8e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KUM60911.1 - 0.0035 16.9 0.0 0.0095 15.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KUM60911.1 - 0.13 11.7 0.2 7.8 5.9 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain Band_7 PF01145.20 KUM60912.1 - 2.5e-24 86.1 2.4 3.2e-24 85.8 1.7 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Ank_2 PF12796.2 KUM60913.1 - 1.7e-07 31.4 0.1 9.3e-07 29.1 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KUM60913.1 - 0.057 13.9 0.0 2.8 8.5 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.25 KUM60913.1 - 0.064 13.0 0.0 0.18 11.6 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat DEAD PF00270.24 KUM60914.1 - 7.7e-17 61.2 0.0 2.1e-16 59.8 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM60914.1 - 5.3e-09 35.8 0.1 1.2e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KUM60914.1 - 8e-06 25.8 0.0 2e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.1 KUM60914.1 - 0.0012 19.0 0.0 0.0047 17.0 0.0 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF4332 PF14229.1 KUM60914.1 - 0.0074 16.2 0.1 0.025 14.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) AAA_22 PF13401.1 KUM60914.1 - 0.0075 16.4 0.1 0.047 13.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain Sigma70_r4 PF04545.11 KUM60914.1 - 0.067 12.5 0.0 0.33 10.2 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 TATR PF03430.8 KUM60915.1 - 0.99 7.9 9.2 1.1 7.8 6.4 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DUF3807 PF12720.2 KUM60915.1 - 1.5 8.9 12.6 2 8.5 8.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) VTC PF09359.5 KUM60916.1 - 4.9e-102 340.7 0.3 8.2e-102 340.0 0.2 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 KUM60916.1 - 1.2e-24 87.5 11.7 1.4e-22 80.7 7.2 3.0 2 1 0 2 2 2 1 SPX domain DUF202 PF02656.10 KUM60916.1 - 4.2e-11 42.9 4.3 4.2e-11 42.9 3.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Fungal_trans PF04082.13 KUM60917.1 - 4.1e-26 91.4 1.3 5.7e-26 90.9 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM60917.1 - 0.00038 20.2 11.3 0.00067 19.5 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SNF2_N PF00176.18 KUM60918.1 - 6.8e-21 74.3 0.0 3.3e-16 58.9 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.12 KUM60918.1 - 1.6e-13 50.4 0.0 5.1e-13 48.8 0.0 1.9 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase zf-RING_5 PF14634.1 KUM60918.1 - 0.00021 20.9 25.9 0.00022 20.8 5.6 2.7 2 0 0 2 2 2 2 zinc-RING finger domain Helicase_C PF00271.26 KUM60918.1 - 0.00026 20.8 0.0 0.0047 16.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 KUM60918.1 - 2.4 8.2 23.7 0.77 9.8 5.2 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KUM60918.1 - 4.6 6.9 22.6 0.047 13.3 4.2 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KUM60918.1 - 7 6.4 16.3 0.54 10.0 4.6 2.7 2 0 0 2 2 2 0 RING-type zinc-finger CSTF2_hinge PF14327.1 KUM60919.1 - 6.8e-29 99.7 2.7 6.8e-29 99.7 1.9 2.3 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 KUM60919.1 - 1.4e-19 69.4 0.0 2.5e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 KUM60919.1 - 1.6e-17 62.5 8.9 1.6e-17 62.5 6.1 2.5 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal RRM_6 PF14259.1 KUM60919.1 - 7e-17 61.1 0.0 1.2e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM60919.1 - 2.2e-07 30.6 0.0 3.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 KUM60919.1 - 0.017 14.6 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein family 7 Limkain-b1 PF11608.3 KUM60919.1 - 0.086 12.6 0.0 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 Limkain b1 AMP-binding PF00501.23 KUM60920.1 - 0 1026.4 0.0 2.6e-77 259.9 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 KUM60920.1 - 1.6e-141 470.4 0.0 1.4e-44 152.1 0.0 5.3 4 1 0 4 4 4 4 Condensation domain PP-binding PF00550.20 KUM60920.1 - 5.9e-41 138.5 5.6 8.6e-10 38.7 0.1 4.8 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KUM60920.1 - 2.7e-24 85.8 0.1 6.1e-08 33.5 0.0 4.9 4 0 0 4 4 4 4 AMP-binding enzyme C-terminal domain MRP-L51 PF10244.4 KUM60920.1 - 0.36 10.8 0.1 3.2 7.8 0.0 2.6 3 0 0 3 3 3 0 Mitochondrial ribosomal subunit FragX_IP PF05994.6 KUM60920.1 - 0.69 7.6 0.2 1.1 6.9 0.1 1.2 1 0 0 1 1 1 0 Cytoplasmic Fragile-X interacting family Velvet PF11754.3 KUM60922.1 - 0.063 12.8 0.0 0.065 12.8 0.0 1.1 1 0 0 1 1 1 0 Velvet factor Acyltransferase PF01553.16 KUM60923.1 - 1.1e-15 57.1 0.0 3.2e-15 55.7 0.0 1.7 1 1 0 1 1 1 1 Acyltransferase L31 PF09784.4 KUM60924.1 - 2e-47 159.4 2.4 2.2e-47 159.3 1.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 DEAD PF00270.24 KUM60925.1 - 3.8e-41 140.3 1.9 5.9e-41 139.7 0.6 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM60925.1 - 1.1e-22 79.6 0.1 4.5e-12 45.6 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 KUM60925.1 - 5.9e-07 29.5 0.9 2.1e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit LRR_4 PF12799.2 KUM60926.1 - 0.55 9.9 4.8 12 5.6 0.1 4.0 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) FAD_binding_4 PF01565.18 KUM60927.1 - 6.2e-20 71.0 0.5 1.2e-19 70.1 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KUM60927.1 - 0.0013 18.5 0.0 0.0031 17.3 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Laminin_II PF06009.7 KUM60928.1 - 0.041 13.6 1.6 2.6 7.8 0.0 2.9 1 1 2 3 3 3 0 Laminin Domain II adh_short PF00106.20 KUM60929.1 - 2.3e-12 47.1 0.0 3.4e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM60929.1 - 0.00057 19.6 0.0 0.0019 17.8 0.0 1.7 2 0 0 2 2 2 1 KR domain Deltaretro_Tax PF05599.6 KUM60929.1 - 0.094 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Deltaretrovirus Tax protein DUF605 PF04652.11 KUM60930.1 - 1.3 8.3 13.1 1.3 8.3 9.1 1.0 1 0 0 1 1 1 0 Vta1 like Hid1 PF12722.2 KUM60930.1 - 1.4 6.4 5.6 1.6 6.3 3.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein tRNA-synt_1d PF00750.14 KUM60931.1 - 8.3e-82 274.8 8.2 5.3e-79 265.6 5.7 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 KUM60931.1 - 3.3e-27 94.8 0.2 3.3e-27 94.8 0.1 1.8 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 KUM60931.1 - 8.5e-09 35.8 0.1 1.2e-07 32.1 0.0 2.5 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain Fer4_12 PF13353.1 KUM60932.1 - 0.16 12.1 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain ABC_tran PF00005.22 KUM60934.1 - 1.5e-27 96.6 0.1 2.4e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 KUM60934.1 - 1e-26 93.4 29.5 1.7e-26 92.7 20.4 1.3 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.1 KUM60934.1 - 5.8e-07 29.7 0.0 0.0059 16.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KUM60934.1 - 1.5e-06 28.3 0.1 2.5e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 KUM60934.1 - 1.5e-05 24.8 0.1 2.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KUM60934.1 - 3.1e-05 23.2 0.0 5.6e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 KUM60934.1 - 0.00016 21.7 0.0 0.0003 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KUM60934.1 - 0.00027 20.3 0.0 0.00092 18.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KUM60934.1 - 0.00065 20.5 0.0 0.0013 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KUM60934.1 - 0.00067 19.8 0.1 0.0061 16.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 KUM60934.1 - 0.0014 18.7 0.0 0.0061 16.7 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KUM60934.1 - 0.0021 17.5 0.0 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 KUM60934.1 - 0.0024 18.1 0.0 0.0055 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KUM60934.1 - 0.0027 17.4 0.0 0.0053 16.4 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase ArgK PF03308.11 KUM60934.1 - 0.0029 16.4 0.2 0.0047 15.7 0.1 1.2 1 0 0 1 1 1 1 ArgK protein Rad17 PF03215.10 KUM60934.1 - 0.0033 16.1 0.0 0.0051 15.5 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 KUM60934.1 - 0.0034 16.8 0.0 0.0069 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain AAA_19 PF13245.1 KUM60934.1 - 0.0048 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 KUM60934.1 - 0.0061 16.2 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain MobB PF03205.9 KUM60934.1 - 0.0066 16.1 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 KUM60934.1 - 0.0087 15.6 0.4 0.027 14.0 0.2 1.8 1 1 1 2 2 1 1 AAA domain SMC_N PF02463.14 KUM60934.1 - 0.0099 15.1 0.1 0.065 12.4 0.1 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KUM60934.1 - 0.011 14.8 0.0 2.1 7.2 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.14 KUM60934.1 - 0.013 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 KUM60934.1 - 0.015 15.4 0.0 0.043 13.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.18 KUM60934.1 - 0.02 14.8 0.0 0.052 13.5 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase NB-ARC PF00931.17 KUM60934.1 - 0.022 13.6 0.0 0.18 10.6 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.9 KUM60934.1 - 0.025 14.3 0.0 0.1 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KUM60934.1 - 0.028 14.3 0.0 0.063 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KUM60934.1 - 0.045 13.3 0.0 0.095 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 SbcCD_C PF13558.1 KUM60934.1 - 0.045 13.6 0.0 0.15 12.0 0.0 1.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.10 KUM60934.1 - 0.048 13.3 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_29 PF13555.1 KUM60934.1 - 0.06 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 KUM60934.1 - 0.061 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_35 PF14516.1 KUM60934.1 - 0.099 11.2 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain ATP-synt_ab PF00006.20 KUM60934.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain T2SE PF00437.15 KUM60934.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.17 KUM60934.1 - 0.15 11.4 0.2 0.28 10.6 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain FAD_binding_6 PF00970.19 KUM60936.1 - 4.2e-30 103.8 0.0 6.7e-30 103.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KUM60936.1 - 6.7e-27 94.2 0.0 1.1e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KUM60936.1 - 1.7e-07 31.2 0.0 7.6e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KUM60936.1 - 0.00056 19.8 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DUF4176 PF13780.1 KUM60936.1 - 0.081 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4176) DUF3605 PF12239.3 KUM60937.1 - 3e-55 186.3 0.0 3.9e-55 186.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) CcoS PF03597.10 KUM60939.1 - 0.2 11.1 1.9 0.41 10.1 1.3 1.5 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Spherulin4 PF12138.3 KUM60940.1 - 3.6e-45 154.3 0.1 4.1e-45 154.1 0.1 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 E1_dh PF00676.15 KUM60941.1 - 2.7e-88 295.5 0.0 3.2e-88 295.3 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KUM60941.1 - 1.5e-05 24.5 0.1 0.00035 20.1 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.5 KUM60941.1 - 0.029 12.9 0.0 0.048 12.1 0.0 1.3 1 0 0 1 1 1 0 XFP N-terminal domain DUF1470 PF07336.6 KUM60941.1 - 0.03 14.6 0.0 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1470) DXP_synthase_N PF13292.1 KUM60941.1 - 0.038 12.9 0.0 0.23 10.3 0.0 2.1 3 0 0 3 3 3 0 1-deoxy-D-xylulose-5-phosphate synthase FAA_hydrolase_N PF09298.6 KUM60941.1 - 0.07 13.1 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal SGS PF05002.10 KUM60941.1 - 0.15 11.8 2.5 3 7.6 0.9 2.7 2 1 0 2 2 2 0 SGS domain LTXXQ PF07813.7 KUM60941.1 - 0.16 12.4 3.1 0.36 11.2 2.1 1.6 1 0 0 1 1 1 0 LTXXQ motif family protein DUF217 PF02697.9 KUM60941.1 - 0.92 9.7 4.6 5 7.4 0.7 2.3 1 1 1 2 2 2 0 Uncharacterized ACR, COG1753 NUDIX PF00293.23 KUM60942.1 - 5.6e-05 22.7 0.2 6.8e-05 22.5 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain Y_phosphatase3 PF13350.1 KUM60943.1 - 1.9e-37 129.0 0.0 2.7e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KUM60943.1 - 1e-05 25.0 0.0 1.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3C PF13348.1 KUM60943.1 - 1.4e-05 25.1 0.1 4.6e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 KUM60943.1 - 0.0002 20.7 0.0 0.00031 20.1 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KUM60943.1 - 0.0042 17.1 0.0 0.0069 16.4 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate DUF3147 PF11345.3 KUM60943.1 - 0.033 14.2 0.2 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3147) Myotub-related PF06602.9 KUM60943.1 - 0.088 11.5 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Glyco_hydro_2 PF00703.16 KUM60944.1 - 1.1e-07 32.2 0.0 3.6e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Hira PF07569.6 KUM60944.1 - 0.16 11.2 0.1 0.3 10.2 0.1 1.4 1 0 0 1 1 1 0 TUP1-like enhancer of split NAGidase PF07555.8 KUM60945.1 - 7.7e-104 346.8 0.8 1.2e-103 346.2 0.6 1.3 1 0 0 1 1 1 1 beta-N-acetylglucosaminidase Glyco_hydro_20b PF02838.10 KUM60945.1 - 2.1e-22 79.9 0.1 4.1e-22 79.0 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_67N PF03648.9 KUM60945.1 - 0.00028 20.9 0.1 0.00059 19.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus UPF0075 PF03702.9 KUM60946.1 - 3e-84 283.0 0.0 3.5e-84 282.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) Zn_clus PF00172.13 KUM60947.1 - 7.2e-06 25.8 8.9 1.1e-05 25.2 6.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KUM60948.1 - 4.7e-09 35.5 0.0 7e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain 4HBT PF03061.17 KUM60949.1 - 5e-09 36.1 0.0 1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily G-gamma PF00631.17 KUM60951.1 - 2.3 8.0 6.9 1.5e+02 2.2 1.7 4.7 2 2 1 3 3 3 0 GGL domain SDA1 PF05285.7 KUM60951.1 - 6.2 6.0 30.0 9.5 5.3 20.8 1.3 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 KUM60951.1 - 9.4 4.5 32.3 14 4.0 22.4 1.1 1 0 0 1 1 1 0 Daxx Family CTP_transf_2 PF01467.21 KUM60952.1 - 8.4e-28 97.4 0.0 1e-27 97.0 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase Mnd1 PF03962.10 KUM60952.1 - 0.15 11.7 0.0 0.33 10.5 0.0 1.5 1 1 1 2 2 2 0 Mnd1 family SIS PF01380.17 KUM60953.1 - 5.5e-14 51.9 0.0 1.6e-12 47.1 0.0 2.3 2 0 0 2 2 2 1 SIS domain SIS_2 PF13580.1 KUM60953.1 - 4.8e-06 26.3 0.0 0.0014 18.3 0.0 2.3 1 1 1 2 2 2 2 SIS domain HECT PF00632.20 KUM60955.1 - 2.7e-81 273.1 0.0 4.2e-81 272.5 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HEAT PF02985.17 KUM60955.1 - 0.0078 16.2 0.5 0.28 11.3 0.0 3.8 4 0 0 4 4 4 1 HEAT repeat OAD_beta PF03977.8 KUM60955.1 - 0.041 12.6 0.1 0.069 11.8 0.1 1.2 1 0 0 1 1 1 0 Na+-transporting oxaloacetate decarboxylase beta subunit Arm PF00514.18 KUM60955.1 - 7.2 6.6 9.8 6.7 6.7 0.1 5.0 5 1 1 6 6 6 0 Armadillo/beta-catenin-like repeat Ubie_methyltran PF01209.13 KUM60956.1 - 2.7e-81 272.1 0.0 3.6e-81 271.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KUM60956.1 - 1.2e-13 51.2 0.0 2.3e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM60956.1 - 2.1e-13 50.1 0.0 3.1e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM60956.1 - 3.2e-11 43.5 0.0 6.4e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM60956.1 - 1.6e-10 41.2 0.0 6e-10 39.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM60956.1 - 1.2e-09 38.1 0.0 1.9e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM60956.1 - 3.1e-07 30.9 0.0 7.5e-07 29.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KUM60956.1 - 6.2e-05 23.0 0.0 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KUM60956.1 - 0.011 15.4 0.0 0.07 12.7 0.0 2.2 2 1 0 2 2 2 0 Hypothetical methyltransferase DUF3649 PF12365.3 KUM60956.1 - 0.83 9.2 3.0 0.59 9.6 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3649) AA_permease PF00324.16 KUM60957.1 - 2.2e-103 346.1 43.3 2.5e-103 345.9 30.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KUM60957.1 - 1.2e-33 116.3 46.7 1.4e-33 116.1 32.4 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2665 PF11654.3 KUM60957.1 - 3 7.4 4.7 1.6 8.4 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2665) Aldedh PF00171.17 KUM60958.1 - 1.7e-105 353.0 0.1 2.1e-105 352.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AP_endonuc_2 PF01261.19 KUM60959.1 - 4.4e-34 117.6 0.0 5.6e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel zf-RING_4 PF14570.1 KUM60961.1 - 2.7e-19 68.4 13.7 4.9e-19 67.6 9.5 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 KUM60961.1 - 2.3e-05 23.9 6.0 4.2e-05 23.1 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 KUM60961.1 - 2.7e-05 23.7 0.0 6.2e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.1 KUM60961.1 - 0.00085 19.1 9.0 0.0015 18.3 6.3 1.4 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.7 KUM60961.1 - 0.0014 17.8 2.2 0.0027 16.9 1.5 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger Baculo_IE-1 PF05290.6 KUM60961.1 - 0.0018 18.0 4.5 0.0033 17.1 3.1 1.4 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) RRM_5 PF13893.1 KUM60961.1 - 0.0021 17.8 0.0 0.0046 16.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.20 KUM60961.1 - 0.039 13.6 12.2 0.08 12.6 8.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RRM_6 PF14259.1 KUM60961.1 - 0.15 12.0 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.1 KUM60961.1 - 0.23 11.5 11.1 0.4 10.7 7.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KUM60961.1 - 8.8 6.3 12.6 90 3.0 8.8 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Complex1_30kDa PF00329.14 KUM60962.1 - 2.3e-36 124.1 0.0 3.2e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit BUD22 PF09073.5 KUM60963.1 - 3.9e-91 306.2 15.0 4.9e-91 305.9 10.4 1.0 1 0 0 1 1 1 1 BUD22 Fungal_trans PF04082.13 KUM60964.1 - 6.2e-26 90.8 0.1 1.2e-25 89.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM60964.1 - 2.4e-05 24.1 10.8 4.1e-05 23.4 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Flavi_NS5 PF00972.15 KUM60964.1 - 0.053 11.4 0.1 0.078 10.8 0.1 1.1 1 0 0 1 1 1 0 Flavivirus RNA-directed RNA polymerase Syntaxin PF00804.20 KUM60964.1 - 0.12 12.6 0.3 0.34 11.0 0.2 1.8 1 0 0 1 1 1 0 Syntaxin Shikimate_DH PF01488.15 KUM60965.1 - 0.00016 21.7 0.0 0.00076 19.5 0.0 2.0 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pro_dh PF01619.13 KUM60966.1 - 1.5e-33 116.1 0.1 2.2e-33 115.6 0.1 1.2 1 0 0 1 1 1 1 Proline dehydrogenase AA_permease PF00324.16 KUM60967.1 - 3.4e-121 404.8 47.4 4.2e-121 404.6 32.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KUM60967.1 - 5.6e-27 94.3 52.1 7.1e-27 93.9 36.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2665 PF11654.3 KUM60967.1 - 0.014 14.9 0.6 0.038 13.5 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2665) 6PGD PF00393.14 KUM60968.1 - 4.2e-60 203.4 0.0 6.2e-60 202.8 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KUM60968.1 - 3.1e-37 127.9 0.0 6.6e-37 126.8 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 KUM60968.1 - 9e-05 22.1 0.1 0.00016 21.3 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KUM60968.1 - 0.002 17.3 0.0 0.0042 16.2 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KUM60968.1 - 0.006 16.9 0.0 0.018 15.4 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 KUM60968.1 - 0.014 14.7 0.1 0.048 13.0 0.1 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KUM60968.1 - 0.021 14.5 0.1 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 KUM60968.1 - 0.037 13.4 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Melibiase PF02065.13 KUM60969.1 - 1.5e-23 83.1 1.2 6e-21 74.5 0.8 3.0 1 1 0 1 1 1 1 Melibiase Exo_endo_phos PF03372.18 KUM60970.1 - 1.2e-22 81.0 0.0 2.2e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 KUM60970.1 - 0.19 11.6 3.7 0.59 10.1 0.9 3.0 2 0 0 2 2 2 0 WD domain, G-beta repeat PALP PF00291.20 KUM60971.1 - 8.3e-62 209.1 0.1 1e-61 208.8 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Tim17 PF02466.14 KUM60972.1 - 6.8e-52 174.8 7.5 9.1e-52 174.4 5.2 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4048 PF13257.1 KUM60974.1 - 4.6e-93 311.5 21.9 4.6e-93 311.5 15.2 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4048) Myosin_HC-like PF07058.6 KUM60974.1 - 0.12 11.4 1.4 0.27 10.3 1.0 1.6 1 0 0 1 1 1 0 Myosin II heavy chain-like zf-CHY PF05495.7 KUM60975.1 - 9.5e-14 51.3 22.4 1.3e-13 50.9 15.5 1.2 1 0 0 1 1 1 1 CHY zinc finger C1_4 PF07975.7 KUM60975.1 - 0.014 15.3 12.8 0.12 12.4 4.7 2.5 1 1 1 2 2 2 0 TFIIH C1-like domain Zn_Tnp_IS1595 PF12760.2 KUM60975.1 - 0.39 10.5 13.3 13 5.7 7.1 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Transposase_21 PF02992.9 KUM60975.1 - 0.54 9.2 3.3 0.7 8.9 2.3 1.3 1 0 0 1 1 1 0 Transposase family tnp2 zf-TFIIB PF13453.1 KUM60975.1 - 1.6 8.0 8.2 6 6.1 0.0 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-RING_3 PF14369.1 KUM60975.1 - 2.9 7.9 13.2 0.86 9.6 4.8 2.6 1 1 1 2 2 2 0 zinc-finger Evr1_Alr PF04777.8 KUM60975.1 - 4.1 7.3 14.0 25 4.8 7.0 2.8 1 1 1 2 2 2 0 Erv1 / Alr family Proteasome PF00227.21 KUM60976.1 - 3.5e-55 186.2 0.1 4.9e-55 185.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KUM60976.1 - 6.3e-14 50.9 0.1 6.3e-14 50.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.7 KUM60976.1 - 0.069 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) zf-RanBP PF00641.13 KUM60977.1 - 1e-20 72.4 9.1 6.4e-11 41.1 1.1 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 KUM60977.1 - 2.4e-08 33.4 0.0 6e-08 32.2 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM60977.1 - 8.4e-07 28.8 0.0 8.1e-06 25.7 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 KUM60977.1 - 2.9e-06 27.6 0.0 4.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DZR PF12773.2 KUM60977.1 - 0.52 10.1 8.3 0.82 9.5 0.8 2.5 2 0 0 2 2 2 0 Double zinc ribbon Cnd3 PF12719.2 KUM60978.1 - 1.9e-95 319.2 0.3 2.5e-94 315.6 0.0 2.7 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 KUM60978.1 - 3.4e-09 36.8 3.5 2.8e-06 27.5 0.1 4.2 2 1 2 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 KUM60978.1 - 6.4e-08 32.8 2.5 0.00011 22.6 0.1 4.6 3 0 0 3 3 3 1 HEAT-like repeat HEAT PF02985.17 KUM60978.1 - 3.9e-06 26.4 0.5 0.1 12.7 0.0 4.6 4 0 0 4 4 4 2 HEAT repeat Cohesin_HEAT PF12765.2 KUM60978.1 - 0.037 13.9 0.6 0.46 10.5 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Lactamase_B PF00753.22 KUM60979.1 - 3.7e-16 59.3 3.2 5.8e-16 58.7 2.2 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KUM60979.1 - 0.0019 17.7 0.6 0.0024 17.4 0.4 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Epimerase PF01370.16 KUM60980.1 - 1.6e-17 63.7 0.0 2.7e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KUM60980.1 - 1.1e-10 40.6 0.0 5.5e-10 38.4 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KUM60980.1 - 1.2e-10 41.6 0.2 7.2e-10 39.1 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KUM60980.1 - 3.9e-07 29.2 0.1 0.005 15.8 0.0 2.4 1 1 1 2 2 2 2 Male sterility protein adh_short PF00106.20 KUM60980.1 - 1.7e-06 28.0 0.2 6.5e-06 26.1 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 KUM60980.1 - 0.00075 18.8 0.0 0.0066 15.7 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 KUM60980.1 - 0.0018 17.2 0.0 0.0032 16.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 KUM60980.1 - 0.16 11.6 0.7 1.5 8.4 0.5 2.1 1 1 0 1 1 1 0 KR domain TRI5 PF06330.6 KUM60981.1 - 4.2e-25 88.2 1.4 5.4e-25 87.8 1.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) MFS_1 PF07690.11 KUM60982.1 - 2.6e-37 128.3 48.9 5.1e-37 127.4 33.5 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM60982.1 - 1.1e-14 53.5 12.0 1.1e-14 53.5 8.3 2.1 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) zf-CHCC PF10276.4 KUM60983.1 - 8.6e-17 60.6 0.7 1.5e-16 59.9 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger domain UPF0047 PF01894.12 KUM60984.1 - 7.1e-41 138.7 0.0 8e-41 138.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 CoaE PF01121.15 KUM60985.1 - 1.1e-41 142.2 0.0 1.5e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 KUM60985.1 - 0.0027 18.5 0.1 0.0041 17.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KUM60985.1 - 0.043 14.1 1.9 0.54 10.5 1.3 2.3 1 1 0 1 1 1 0 AAA domain 2TM PF13239.1 KUM60985.1 - 0.05 13.6 0.6 0.1 12.6 0.4 1.5 1 0 0 1 1 1 0 2TM domain RXT2_N PF08595.6 KUM60986.1 - 0.27 11.0 2.9 0.18 11.6 0.7 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal MPP6 PF10175.4 KUM60986.1 - 0.36 11.2 0.1 0.36 11.2 0.1 2.7 3 1 0 3 3 3 0 M-phase phosphoprotein 6 Lipase_3 PF01764.20 KUM60987.1 - 1.2e-36 125.4 0.0 1.7e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.11 KUM60987.1 - 1.2e-08 34.5 0.2 2.4e-08 33.6 0.2 1.5 1 0 0 1 1 1 1 Lipase 3 N-terminal region Abhydrolase_8 PF06259.7 KUM60987.1 - 0.00045 19.7 0.0 0.0017 17.8 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase DUF2974 PF11187.3 KUM60987.1 - 0.01 15.2 0.1 0.029 13.7 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Thioesterase PF00975.15 KUM60987.1 - 0.021 15.0 0.0 0.029 14.6 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF3431 PF11913.3 KUM60988.1 - 1.4e-91 305.9 0.2 5e-91 304.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3431) DUF3357 PF11837.3 KUM60988.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Pkinase PF00069.20 KUM60992.1 - 5e-08 32.4 0.0 2.9e-06 26.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain DUF4066 PF13278.1 KUM60994.1 - 9.1e-30 103.1 0.0 1.1e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KUM60994.1 - 2.6e-06 26.9 0.0 3.8e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Fungal_trans PF04082.13 KUM60995.1 - 5.1e-05 22.2 0.4 0.00017 20.5 0.0 2.0 1 1 0 2 2 2 1 Fungal specific transcription factor domain Glyco_hydro_32N PF00251.15 KUM60996.1 - 1.8e-90 303.4 3.5 2.3e-90 303.0 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 KUM60996.1 - 1.6e-15 57.2 0.2 3.3e-15 56.2 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF2531 PF10748.4 KUM60996.1 - 0.023 13.8 1.0 0.14 11.3 0.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2531) DUF3431 PF11913.3 KUM60998.1 - 2.2e-81 272.5 0.1 2.7e-81 272.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) PP1 PF07430.6 KUM60998.1 - 0.033 13.7 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Phloem filament protein PP1 F-box-like PF12937.2 KUM60999.1 - 1.5e-05 24.5 0.3 4.4e-05 23.1 0.2 1.9 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KUM60999.1 - 0.026 14.1 0.1 1.3 8.7 0.0 3.4 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) GFA PF04828.9 KUM61000.1 - 1.8e-11 43.8 1.9 3e-11 43.1 1.3 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-LSD1 PF06943.7 KUM61000.1 - 0.019 14.5 5.5 0.28 10.8 0.7 2.4 2 0 0 2 2 2 0 LSD1 zinc finger ADH_zinc_N PF00107.21 KUM61002.1 - 1.9e-08 33.9 0.2 3.3e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM61002.1 - 1e-07 31.6 0.0 1.7e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NUDIX_2 PF13869.1 KUM61003.1 - 6.5e-81 270.1 0.0 7.8e-81 269.9 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase Metalloenzyme PF01676.13 KUM61004.1 - 1.5e-72 243.9 0.1 1.8e-72 243.7 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 KUM61004.1 - 1.7e-68 230.3 0.0 2.3e-68 229.8 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 KUM61004.1 - 4.6e-10 39.3 0.0 7.9e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KUM61004.1 - 2.8e-05 23.4 0.0 6.5e-05 22.2 0.0 1.7 1 1 0 1 1 1 1 Sulfatase Alk_phosphatase PF00245.15 KUM61004.1 - 0.029 13.0 0.0 0.13 10.8 0.0 1.8 2 0 0 2 2 2 0 Alkaline phosphatase AP_endonuc_2 PF01261.19 KUM61004.1 - 0.059 12.6 0.0 0.2 10.9 0.0 1.8 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel AMMECR1 PF01871.12 KUM61005.1 - 9.7e-35 119.2 0.0 9.7e-33 112.6 0.0 2.5 1 1 0 1 1 1 1 AMMECR1 DUF572 PF04502.8 KUM61005.1 - 0.17 11.0 6.0 0.23 10.6 4.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) AF-4 PF05110.8 KUM61005.1 - 4 5.1 19.3 5.1 4.8 13.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Pkinase PF00069.20 KUM61006.1 - 1.5e-70 237.3 0.0 2e-70 236.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM61006.1 - 1.7e-30 105.9 0.0 2.2e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM61006.1 - 1.3e-06 27.6 0.0 2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KUM61006.1 - 0.00017 20.6 0.0 0.00033 19.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KUM61006.1 - 0.00021 21.1 0.1 0.00035 20.3 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KUM61006.1 - 0.014 14.7 0.0 0.037 13.3 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL SHMT PF00464.14 KUM61007.1 - 4.8e-208 690.3 0.0 5.5e-208 690.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 KUM61007.1 - 4e-06 26.0 0.0 8.8e-06 24.9 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KUM61007.1 - 9.1e-05 21.3 0.0 0.00013 20.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KUM61007.1 - 0.0031 16.7 0.0 0.005 16.0 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase HNH_2 PF13391.1 KUM61008.1 - 4.4e-14 52.0 0.0 8.6e-14 51.0 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Nop PF01798.13 KUM61010.1 - 7.3e-61 203.8 0.1 1.5e-60 202.8 0.0 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KUM61010.1 - 5.8e-25 86.8 0.4 1.1e-24 85.9 0.3 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KUM61010.1 - 3.9e-22 78.1 0.1 3.9e-22 78.1 0.1 2.8 3 0 0 3 3 3 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.6 KUM61010.1 - 0.14 11.8 28.1 0.26 10.9 19.5 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF1744 PF08490.7 KUM61011.1 - 8.5e-149 495.4 0.0 1.2e-148 494.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 KUM61011.1 - 4.1e-70 236.2 1.0 4.1e-70 236.2 0.7 2.2 2 1 1 3 3 3 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 KUM61011.1 - 2.2e-22 79.4 0.0 9.2e-22 77.4 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 KUM61011.1 - 1.3e-07 31.3 0.0 3.4e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 KUM61011.1 - 9.9e-05 22.2 0.0 0.00037 20.3 0.0 2.0 1 0 0 1 1 1 1 RNase_H superfamily DUF3767 PF12597.3 KUM61012.1 - 6.7e-35 119.3 0.0 1.2e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) TMA7 PF09072.5 KUM61012.1 - 0.014 15.8 3.5 0.031 14.7 2.4 1.5 1 0 0 1 1 1 0 Translation machinery associated TMA7 YXWGXW PF12779.2 KUM61012.1 - 0.084 12.7 1.4 0.18 11.7 1.0 1.6 1 0 0 1 1 1 0 YXWGXW repeat (2 copies) Folliculin PF11704.3 KUM61013.1 - 3.3e-46 156.9 0.0 4.6e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport PCI_Csn8 PF10075.4 KUM61014.1 - 9.3e-48 161.6 0.0 1.2e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 KUM61014.1 - 1.9e-22 79.8 0.1 2.5e-22 79.4 0.1 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Microtub_assoc PF07989.6 KUM61015.1 - 4.1e-24 84.2 5.2 4.1e-24 84.2 3.6 10.3 6 3 6 13 13 13 1 Microtubule associated PACT_coil_coil PF10495.4 KUM61015.1 - 3.8e-23 81.2 0.9 1.5e-22 79.2 0.6 2.2 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Hemagglutinin PF00509.13 KUM61015.1 - 9.5 4.2 11.0 0.52 8.3 2.0 3.0 3 0 0 3 3 3 0 Haemagglutinin SGT1 PF07093.6 KUM61016.1 - 2.4e-148 495.1 29.7 4.7e-147 490.8 20.6 1.9 1 1 0 1 1 1 1 SGT1 protein Prefoldin_2 PF01920.15 KUM61017.1 - 2e-22 78.9 16.0 2.6e-22 78.5 11.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit Spc24 PF08286.6 KUM61017.1 - 0.001 18.7 15.1 0.0029 17.2 2.7 2.1 1 1 0 2 2 2 1 Spc24 subunit of Ndc80 Prefoldin_3 PF13758.1 KUM61017.1 - 0.0045 16.7 5.4 0.0091 15.7 3.7 1.7 1 1 0 1 1 1 1 Prefoldin subunit IncA PF04156.9 KUM61017.1 - 0.0071 15.9 21.3 0.033 13.7 14.8 1.8 1 1 0 1 1 1 1 IncA protein Prefoldin PF02996.12 KUM61017.1 - 0.0099 15.5 12.4 0.021 14.4 8.6 1.5 1 1 0 1 1 1 1 Prefoldin subunit DUF1640 PF07798.6 KUM61017.1 - 0.01 15.8 3.3 0.01 15.8 2.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Atg14 PF10186.4 KUM61017.1 - 0.016 14.1 9.5 0.023 13.6 6.6 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 COG2 PF06148.6 KUM61017.1 - 0.027 14.3 8.1 0.27 11.1 1.4 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 BLOC1_2 PF10046.4 KUM61017.1 - 0.042 13.9 10.9 0.62 10.2 1.1 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_TATA_bd PF12325.3 KUM61017.1 - 0.079 12.7 13.7 0.62 9.7 2.6 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding AAA_27 PF13514.1 KUM61017.1 - 0.082 10.5 13.4 0.095 10.3 9.3 1.0 1 0 0 1 1 1 0 AAA domain Fez1 PF06818.10 KUM61017.1 - 0.15 12.0 13.8 0.033 14.1 2.3 2.0 1 1 0 2 2 2 0 Fez1 Uds1 PF15456.1 KUM61017.1 - 0.16 11.9 7.2 0.27 11.2 5.0 1.4 1 1 0 1 1 1 0 Up-regulated During Septation DivIC PF04977.10 KUM61017.1 - 0.21 11.0 18.8 0.75 9.3 1.1 3.2 2 1 1 3 3 3 0 Septum formation initiator APG6 PF04111.7 KUM61017.1 - 0.24 10.4 17.9 0.046 12.7 4.5 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 KUM61017.1 - 0.24 11.2 15.3 0.65 9.8 1.7 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 KUM61017.1 - 0.24 11.1 16.4 0.43 10.3 2.2 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Cast PF10174.4 KUM61017.1 - 0.25 9.3 16.2 0.066 11.2 8.3 1.7 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone GreA_GreB_N PF03449.10 KUM61017.1 - 0.27 11.3 8.9 0.61 10.1 0.5 3.2 2 1 1 3 3 3 0 Transcription elongation factor, N-terminal MMPL PF03176.10 KUM61017.1 - 0.27 9.8 2.7 0.33 9.6 1.9 1.3 1 1 0 1 1 1 0 MMPL family CAML PF14963.1 KUM61017.1 - 0.28 10.5 3.0 2 7.7 0.1 2.0 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand Prominin PF05478.6 KUM61017.1 - 0.34 8.4 7.9 0.38 8.2 5.5 1.0 1 0 0 1 1 1 0 Prominin Mto2_bdg PF12808.2 KUM61017.1 - 0.34 11.0 4.5 7.2 6.8 0.0 2.8 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Spc7 PF08317.6 KUM61017.1 - 0.36 9.4 14.3 0.46 9.0 9.9 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein TBPIP PF07106.8 KUM61017.1 - 0.45 10.0 13.4 1 8.9 2.3 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GAS PF13851.1 KUM61017.1 - 0.51 9.5 15.0 2 7.5 2.3 2.1 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.2 KUM61017.1 - 0.59 9.9 18.2 1.4 8.8 3.8 2.1 2 0 0 2 2 2 0 Tropomyosin like CorA PF01544.13 KUM61017.1 - 0.67 8.9 8.1 5.6 5.9 5.6 2.0 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein WEMBL PF05701.6 KUM61017.1 - 0.82 8.0 18.1 3.5 5.9 12.4 1.8 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DUF948 PF06103.6 KUM61017.1 - 0.84 9.5 9.1 1.5 8.7 0.8 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Remorin_C PF03763.8 KUM61017.1 - 0.84 9.1 10.4 0.11 12.0 4.3 1.7 2 0 0 2 2 2 0 Remorin, C-terminal region Spectrin PF00435.16 KUM61017.1 - 0.87 9.9 14.2 0.96 9.7 3.2 2.2 2 0 0 2 2 2 0 Spectrin repeat DUF904 PF06005.7 KUM61017.1 - 1.2 9.4 17.6 1.8 8.8 3.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) TcdA_TcdB PF12919.2 KUM61017.1 - 1.4 7.2 6.0 2 6.8 4.1 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain DUF972 PF06156.8 KUM61017.1 - 1.7 9.0 13.3 3.6 7.9 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Sas10_Utp3 PF04000.10 KUM61017.1 - 1.7 8.9 7.1 1.5 9.0 1.0 2.3 1 1 0 2 2 2 0 Sas10/Utp3/C1D family DUF848 PF05852.6 KUM61017.1 - 1.7 8.5 11.9 2.9 7.7 1.5 2.1 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) NPV_P10 PF05531.7 KUM61017.1 - 1.9 8.7 9.2 7.7 6.8 2.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Nup54 PF13874.1 KUM61017.1 - 1.9 8.1 12.5 1.5 8.4 3.3 2.1 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Streptin-Immun PF11083.3 KUM61017.1 - 2.1 8.4 7.3 2.7 8.0 1.0 2.3 1 1 0 2 2 2 0 Lantibiotic streptin immunity protein bZIP_1 PF00170.16 KUM61017.1 - 2.5 8.1 9.4 6.3 6.8 1.2 2.5 2 1 0 2 2 2 0 bZIP transcription factor Chibby PF14645.1 KUM61017.1 - 2.5 7.9 6.6 14 5.5 1.2 2.8 1 1 2 3 3 3 0 Chibby family Occludin_ELL PF07303.8 KUM61017.1 - 2.6 8.8 8.2 5.6 7.7 0.9 2.2 1 1 0 2 2 2 0 Occludin homology domain DUF1664 PF07889.7 KUM61017.1 - 2.6 7.8 8.7 6 6.6 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fmp27_WPPW PF10359.4 KUM61017.1 - 2.8 6.2 11.9 2.4 6.4 1.6 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain SPX PF03105.14 KUM61017.1 - 2.8 7.6 6.1 4.1 7.1 4.2 1.2 1 0 0 1 1 1 0 SPX domain DUF4140 PF13600.1 KUM61017.1 - 2.8 8.4 13.9 7.3 7.0 2.4 2.9 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Macoilin PF09726.4 KUM61017.1 - 2.9 6.0 15.2 26 2.9 10.5 1.9 1 1 0 1 1 1 0 Transmembrane protein Mnd1 PF03962.10 KUM61017.1 - 3.1 7.4 16.4 3.6 7.1 3.1 2.0 1 1 1 2 2 2 0 Mnd1 family ADIP PF11559.3 KUM61017.1 - 3.6 7.4 16.2 0.71 9.7 3.4 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.6 KUM61017.1 - 3.7 7.5 10.5 15 5.5 1.8 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF4200 PF13863.1 KUM61017.1 - 4.3 7.2 15.4 3 7.8 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) FliJ PF02050.11 KUM61017.1 - 4.7 7.2 18.6 5.3 7.1 4.1 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein FTA4 PF13093.1 KUM61017.1 - 5 6.5 12.7 1.6 8.1 2.4 2.2 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Viral_P18 PF04521.8 KUM61017.1 - 6.5 6.2 9.6 5.9 6.3 0.7 2.4 2 1 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DivIVA PF05103.8 KUM61017.1 - 7.3 6.6 15.3 3.1 7.8 3.9 2.5 1 1 1 2 2 2 0 DivIVA protein CDC37_N PF03234.9 KUM61017.1 - 7.9 6.7 9.5 13 6.0 6.6 1.4 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF3847 PF12958.2 KUM61017.1 - 8.4 6.2 13.1 4.3 7.1 2.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) DUF342 PF03961.8 KUM61017.1 - 9.9 4.4 12.2 1.2e+02 0.8 8.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF342) AAA PF00004.24 KUM61018.1 - 2.8e-42 144.0 0.0 4.7e-42 143.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KUM61018.1 - 2.3e-28 97.8 0.0 1.1e-27 95.6 0.0 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 KUM61018.1 - 3.6e-22 78.0 1.4 3.6e-22 78.0 1.0 2.6 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 KUM61018.1 - 1.9e-06 28.6 0.4 1e-05 26.3 0.0 2.7 2 2 0 2 2 1 1 AAA domain RuvB_N PF05496.7 KUM61018.1 - 9.9e-06 24.7 0.0 1.9e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KUM61018.1 - 1.5e-05 24.7 0.0 8.5e-05 22.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KUM61018.1 - 1.6e-05 25.0 0.1 0.0013 18.8 0.1 2.5 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KUM61018.1 - 2.7e-05 23.6 0.0 5.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.8 KUM61018.1 - 3.6e-05 22.8 0.0 0.00088 18.2 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 KUM61018.1 - 3.6e-05 23.2 0.4 0.19 11.1 0.1 3.5 3 1 1 4 4 4 1 AAA domain RNA_helicase PF00910.17 KUM61018.1 - 3.7e-05 23.8 0.0 0.0091 16.1 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 KUM61018.1 - 4.9e-05 23.2 0.0 0.0001 22.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KUM61018.1 - 0.00011 22.3 0.0 0.00094 19.2 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 KUM61018.1 - 0.00011 21.0 0.0 0.00019 20.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_2 PF07724.9 KUM61018.1 - 0.00015 21.7 0.0 0.0057 16.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 KUM61018.1 - 0.00047 20.0 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KUM61018.1 - 0.0035 17.0 0.1 0.31 10.6 0.0 2.8 2 1 1 3 3 3 1 Archaeal ATPase AAA_18 PF13238.1 KUM61018.1 - 0.0048 17.1 0.2 0.017 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 KUM61018.1 - 0.0086 15.6 0.1 0.03 13.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KUM61018.1 - 0.014 14.5 0.1 0.057 12.5 0.1 2.0 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI ResIII PF04851.10 KUM61018.1 - 0.02 14.7 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.7 KUM61018.1 - 0.022 13.8 0.1 0.14 11.2 0.0 2.2 1 1 1 2 2 2 0 Zeta toxin AAA_19 PF13245.1 KUM61018.1 - 0.023 14.4 0.0 0.066 12.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 KUM61018.1 - 0.025 14.2 0.0 0.61 9.7 0.0 2.3 1 1 1 2 2 2 0 NACHT domain USP8_dimer PF08969.6 KUM61018.1 - 0.027 14.4 2.8 0.056 13.3 1.9 1.6 1 0 0 1 1 1 0 USP8 dimerisation domain Torsin PF06309.6 KUM61018.1 - 0.038 13.8 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 Torsin PhoH PF02562.11 KUM61018.1 - 0.04 13.1 0.0 0.092 11.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 KUM61018.1 - 0.052 12.4 0.0 0.086 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 KUM61018.1 - 0.13 12.1 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 KUM61018.1 - 0.14 11.8 0.0 0.59 9.7 0.0 2.0 1 1 0 1 1 1 0 Bacterial dnaA protein DUF4398 PF14346.1 KUM61018.1 - 0.42 10.6 2.7 0.82 9.7 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) Med9 PF07544.8 KUM61019.1 - 4.5e-25 87.2 0.0 7.3e-25 86.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.3 KUM61019.1 - 0.27 11.2 2.2 0.47 10.4 1.5 1.7 1 1 0 1 1 1 0 Subunit 21 of Mediator complex RRM_1 PF00076.17 KUM61020.1 - 4.1e-10 39.1 0.0 7.7e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM61020.1 - 3.4e-07 30.1 0.0 6.4e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3763 PF12592.3 KUM61020.1 - 0.086 12.4 1.7 0.25 10.9 1.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3763) Prominin PF05478.6 KUM61020.1 - 0.091 10.2 0.2 0.14 9.6 0.1 1.1 1 0 0 1 1 1 0 Prominin tRNA-synt_2 PF00152.15 KUM61021.1 - 4e-56 190.2 0.0 5.9e-56 189.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KUM61021.1 - 1.7e-05 24.5 0.0 3.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-like PF12869.2 KUM61021.1 - 0.15 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 tRNA_anti-like Gti1_Pac2 PF09729.4 KUM61022.1 - 2.9e-50 170.4 5.4 1e-49 168.6 0.5 2.8 2 1 0 2 2 2 1 Gti1/Pac2 family Med3 PF11593.3 KUM61022.1 - 0.89 8.7 8.5 1.3 8.1 5.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DAO PF01266.19 KUM61023.1 - 0.0001 21.3 0.2 0.00011 21.2 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KUM61023.1 - 0.0032 17.5 0.0 0.0038 17.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM61023.1 - 0.0058 16.6 0.1 0.0085 16.0 0.1 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KUM61023.1 - 0.054 12.5 0.0 0.061 12.4 0.0 1.1 1 0 0 1 1 1 0 Thi4 family Cpn60_TCP1 PF00118.19 KUM61024.1 - 1.9e-150 501.7 0.1 2.1e-150 501.5 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MOZ_SAS PF01853.13 KUM61025.1 - 1.5e-54 184.0 0.0 1e-51 174.8 0.0 2.1 2 0 0 2 2 2 2 MOZ/SAS family zf-RING_2 PF13639.1 KUM61026.1 - 2.8e-08 33.4 2.9 4.3e-08 32.8 2.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KUM61026.1 - 9.7e-07 28.8 1.0 2.3e-06 27.5 0.7 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KUM61026.1 - 0.00019 21.2 0.7 0.00029 20.6 0.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KUM61026.1 - 0.0012 18.8 2.6 0.0018 18.2 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 KUM61026.1 - 0.0027 17.6 0.4 0.0069 16.3 0.3 1.7 1 0 0 1 1 1 1 zinc-finger zf-C3HC4 PF00097.20 KUM61026.1 - 0.023 14.3 1.3 0.04 13.5 0.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KUM61026.1 - 0.27 10.9 2.4 1.1 8.9 1.7 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Asparaginase_2 PF01112.13 KUM61027.1 - 7.6e-42 143.1 0.0 5.4e-18 64.7 0.0 3.2 3 0 0 3 3 3 3 Asparaginase DUF3483 PF11982.3 KUM61029.1 - 0.1 11.8 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) DUF3450 PF11932.3 KUM61029.1 - 0.35 10.0 3.1 0.1 11.8 0.4 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Glyoxalase PF00903.20 KUM61030.1 - 4.6e-21 75.1 0.9 5e-16 58.8 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KUM61030.1 - 2.1e-13 50.2 0.3 8.7e-07 28.9 0.0 2.6 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KUM61030.1 - 1.3e-08 35.3 0.0 0.0063 17.1 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 KUM61030.1 - 1.1e-06 28.5 0.4 3.4e-05 23.8 0.1 2.6 2 1 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.1 KUM61030.1 - 2.9e-06 27.2 0.4 0.073 12.9 0.1 3.0 3 1 0 3 3 3 2 Glyoxalase-like domain Atx10homo_assoc PF09759.4 KUM61031.1 - 2.5e-30 104.2 0.5 1e-29 102.2 0.1 2.1 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain RYDR_ITPR PF01365.16 KUM61031.1 - 0.13 11.4 0.9 0.39 9.8 0.2 2.0 2 0 0 2 2 2 0 RIH domain Chromo PF00385.19 KUM61033.1 - 9e-12 44.4 1.4 1.9e-11 43.4 0.9 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 KUM61033.1 - 6e-09 35.6 0.5 2.7e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 Chromo shadow domain Rap1_C PF11626.3 KUM61034.1 - 2.7e-22 78.4 0.0 5.6e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 KUM61034.1 - 9.1e-14 51.0 2.2 1.4e-05 24.7 0.2 3.5 3 0 0 3 3 3 2 Rap1 Myb domain Rap1-DNA-bind PF09197.5 KUM61034.1 - 0.031 14.8 0.0 0.19 12.2 0.0 2.3 2 0 0 2 2 2 0 Rap1, DNA-binding zf-DHHC PF01529.15 KUM61035.1 - 6.3e-28 97.3 10.0 9e-28 96.8 6.2 1.7 1 1 1 2 2 2 1 DHHC palmitoyltransferase stn_TNFRSF12A PF12191.3 KUM61035.1 - 0.0007 19.6 1.8 0.0015 18.5 1.3 1.6 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain zf-CHY PF05495.7 KUM61036.1 - 3.7e-19 68.6 15.4 3.7e-19 68.6 10.7 2.4 2 1 0 2 2 2 1 CHY zinc finger Paired_CXXCH_1 PF09699.5 KUM61036.1 - 0.12 11.9 8.2 0.13 11.7 0.2 2.6 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) DZR PF12773.2 KUM61036.1 - 6.6 6.6 18.4 0.34 10.7 0.2 2.8 2 1 0 2 2 2 0 Double zinc ribbon zf-CCCH PF00642.19 KUM61037.1 - 0.0073 15.9 2.9 0.013 15.1 2.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PHF5 PF03660.9 KUM61037.1 - 0.057 13.4 2.5 0.12 12.4 1.7 1.5 1 0 0 1 1 1 0 PHF5-like protein DUF3295 PF11702.3 KUM61038.1 - 1.5e-188 627.9 25.8 1.7e-188 627.7 17.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 KUM61038.1 - 1.6e-12 46.7 1.6 4.1e-12 45.4 1.1 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Cpn60_TCP1 PF00118.19 KUM61039.1 - 2.3e-144 481.6 3.1 2.6e-144 481.4 2.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.11 KUM61039.1 - 0.057 13.3 2.6 21 5.0 0.0 3.4 3 0 0 3 3 3 0 Enolase, N-terminal domain NTP_transferase PF00483.18 KUM61042.1 - 4.9e-29 101.3 0.0 6.8e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 KUM61042.1 - 5.3e-09 35.1 6.2 3.1e-06 26.4 0.1 3.8 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KUM61042.1 - 2.4e-08 34.2 0.0 3.7e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 KUM61042.1 - 0.0058 16.1 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Fucokinase PF07959.7 KUM61042.1 - 0.019 13.5 0.0 0.46 8.9 0.0 2.2 2 0 0 2 2 2 0 L-fucokinase SusD-like_3 PF14322.1 KUM61045.1 - 0.031 14.3 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Starch-binding associating with outer membrane Zn-ribbon_8 PF09723.5 KUM61045.1 - 0.069 13.1 0.1 17 5.4 0.0 2.3 2 0 0 2 2 2 0 Zinc ribbon domain FAA_hydrolase PF01557.13 KUM61046.1 - 5.6e-49 166.5 0.0 7.5e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 KUM61046.1 - 1.5e-23 82.8 0.0 3.2e-23 81.7 0.0 1.6 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal GST_N_3 PF13417.1 KUM61047.1 - 3.3e-13 49.6 0.0 7e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KUM61047.1 - 4.3e-13 49.0 0.0 9e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KUM61047.1 - 6.5e-10 39.0 0.0 1e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KUM61047.1 - 5.8e-06 26.2 0.0 1.2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KUM61047.1 - 0.0062 16.3 0.0 0.011 15.6 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KUM61047.1 - 0.0083 16.5 0.0 0.028 14.8 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TPR_11 PF13414.1 KUM61048.1 - 0.028 14.0 0.0 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 TPR repeat TPR_17 PF13431.1 KUM61048.1 - 0.089 13.0 0.0 0.57 10.5 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat MCM_N PF14551.1 KUM61048.1 - 0.11 12.9 0.0 2 8.9 0.0 2.2 2 0 0 2 2 2 0 MCM N-terminal domain DUF2313 PF10076.4 KUM61048.1 - 0.13 11.6 0.0 0.32 10.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2313) HgmA PF04209.8 KUM61049.1 - 3.6e-192 638.4 0.2 4.1e-192 638.2 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase PCI PF01399.22 KUM61050.1 - 1.2e-11 44.7 0.0 3.1e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 PCI domain Hexokinase_2 PF03727.11 KUM61051.1 - 7.6e-36 123.5 0.0 7.2e-28 97.4 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 KUM61051.1 - 5.6e-33 114.0 0.0 7.8e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Acyl_transf_1 PF00698.16 KUM61053.1 - 5.2e-60 203.4 0.0 7e-60 203.0 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KUM61053.1 - 8.3e-40 136.7 0.0 1.6e-39 135.8 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase DUF915 PF06028.6 KUM61053.1 - 0.21 10.6 0.0 0.4 9.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) KR PF08659.5 KUM61054.1 - 4.8e-60 202.3 0.8 7.9e-60 201.6 0.0 1.8 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KUM61054.1 - 7.7e-47 159.3 0.2 2.1e-46 157.8 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.21 KUM61054.1 - 3.9e-17 62.0 0.1 2e-16 59.7 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KUM61054.1 - 7.8e-12 46.2 0.0 3.7e-11 44.0 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.1 KUM61054.1 - 1.7e-05 24.6 0.0 7.9e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.20 KUM61054.1 - 1.9e-05 24.8 0.8 9.7e-05 22.5 0.5 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site Shikimate_DH PF01488.15 KUM61054.1 - 0.00062 19.8 0.7 0.019 15.0 0.0 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KUM61054.1 - 0.043 13.8 4.0 0.12 12.3 0.1 3.0 3 0 0 3 3 3 0 NADH(P)-binding NmrA PF05368.8 KUM61054.1 - 0.074 12.2 0.1 0.17 11.1 0.1 1.5 1 0 0 1 1 1 0 NmrA-like family NAD_binding_1 PF00175.16 KUM61055.1 - 5.2e-27 94.5 0.0 8.8e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KUM61055.1 - 4.4e-15 55.6 0.0 7.4e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KUM61055.1 - 1.3e-07 31.6 0.0 0.00052 19.9 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KUM61055.1 - 0.074 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain CDO_I PF05995.7 KUM61056.1 - 2.7e-40 137.3 0.1 3.4e-40 137.0 0.1 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 KUM61056.1 - 0.0005 19.4 0.3 0.00077 18.8 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1637) Arylsulfotran_2 PF14269.1 KUM61058.1 - 1.6e-43 149.0 1.2 6e-43 147.1 0.7 2.0 3 0 0 3 3 3 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KUM61058.1 - 4.8e-13 48.4 2.1 3.9e-12 45.4 1.5 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Fungal_trans PF04082.13 KUM61059.1 - 1.5e-16 60.0 2.6 1.5e-16 60.0 1.8 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Stk19 PF10494.4 KUM61060.1 - 3.1e-80 269.2 0.0 3.7e-80 268.9 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Glyco_transf_20 PF00982.16 KUM61061.1 - 1.8e-159 531.2 0.0 3.1e-159 530.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KUM61061.1 - 3.7e-39 134.0 0.1 5.7e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 KUM61061.1 - 0.027 14.0 0.0 0.13 11.8 0.0 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase GST_C PF00043.20 KUM61062.1 - 3.5e-07 30.1 0.1 1.9e-06 27.7 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KUM61062.1 - 1.9e-05 24.7 0.0 0.0033 17.5 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KUM61062.1 - 0.00049 20.2 0.1 0.00093 19.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KUM61062.1 - 0.0018 18.1 0.0 0.0038 17.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KUM61062.1 - 0.0047 16.8 0.1 0.0089 16.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KUM61062.1 - 0.013 15.9 0.0 0.021 15.2 0.0 1.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Na_Ca_ex PF01699.19 KUM61063.1 - 4.1e-47 159.2 32.7 1.1e-24 86.5 8.2 3.1 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Cnd2 PF05786.9 KUM61064.1 - 1.2e-262 873.7 1.7 1.5e-262 873.4 1.2 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 DUF202 PF02656.10 KUM61065.1 - 0.0095 16.1 6.9 0.73 10.1 0.9 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF202) Tetraspannin PF00335.15 KUM61065.1 - 0.04 13.2 8.2 0.095 11.9 5.7 1.7 1 1 0 1 1 1 0 Tetraspanin family FixQ PF05545.6 KUM61065.1 - 0.052 13.1 3.2 0.87 9.2 0.0 3.3 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ TMEM154 PF15102.1 KUM61065.1 - 0.18 11.5 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family zf-H2C2_2 PF13465.1 KUM61066.1 - 8.9e-14 51.0 17.8 8.5e-08 32.1 1.3 3.9 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KUM61066.1 - 9.3e-12 44.5 20.7 0.00089 19.4 3.1 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KUM61066.1 - 1.7e-08 34.2 20.4 0.0035 17.5 3.1 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KUM61066.1 - 0.00017 21.6 7.6 0.14 12.3 1.1 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KUM61066.1 - 0.013 15.6 9.5 0.045 13.8 3.8 2.7 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 KUM61066.1 - 0.018 14.9 13.2 0.049 13.5 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger RRN7 PF11781.3 KUM61066.1 - 0.022 14.2 0.2 8.2 6.0 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-CHCC PF10276.4 KUM61066.1 - 0.029 14.2 3.9 4.9 7.0 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger domain zf-RING_3 PF14369.1 KUM61066.1 - 0.27 11.2 4.9 14 5.8 0.1 3.4 3 0 0 3 3 3 0 zinc-finger DZR PF12773.2 KUM61066.1 - 0.31 10.9 7.0 5 7.0 4.9 2.3 1 1 1 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 KUM61066.1 - 0.44 10.5 9.2 6.3 6.8 2.3 3.1 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2HC_2 PF13913.1 KUM61066.1 - 0.67 9.6 8.8 0.041 13.5 1.3 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-CHY PF05495.7 KUM61066.1 - 0.67 10.1 6.2 1.5 9.0 4.3 1.6 1 0 0 1 1 1 0 CHY zinc finger zinc-ribbons_6 PF07191.7 KUM61066.1 - 1.1 9.1 4.2 2 8.2 1.5 2.1 2 0 0 2 2 2 0 zinc-ribbons HypA PF01155.14 KUM61066.1 - 2.5 7.8 4.1 2.6 7.7 1.7 1.7 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family FYVE PF01363.16 KUM61066.1 - 4.5 7.2 10.8 2.7 7.9 2.2 2.4 1 1 1 2 2 2 0 FYVE zinc finger zf-C2H2_2 PF12756.2 KUM61066.1 - 9 6.4 14.4 1.6 8.8 0.7 3.9 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) FYDLN_acid PF09538.5 KUM61066.1 - 9.5 6.8 11.3 0.95 10.0 0.8 3.4 2 2 1 3 3 3 0 Protein of unknown function (FYDLN_acid) DUF3074 PF11274.3 KUM61067.1 - 5.3e-33 114.2 0.0 6.9e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) ketoacyl-synt PF00109.21 KUM61068.1 - 5.1e-71 239.1 0.0 5.8e-71 238.9 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.18 KUM61068.1 - 0.00046 19.2 0.0 0.00075 18.5 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 KUM61068.1 - 0.0037 16.8 1.0 0.035 13.7 0.7 2.2 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FSH1 PF03959.8 KUM61069.1 - 1.1e-11 44.5 0.0 1.6e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF3253 PF11625.3 KUM61069.1 - 0.041 13.7 0.0 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) Cutinase PF01083.17 KUM61070.1 - 7.9e-17 61.5 0.0 1.1e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 Cutinase ADK PF00406.17 KUM61072.1 - 1.6e-42 144.8 0.0 2.2e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_33 PF13671.1 KUM61072.1 - 3e-08 33.6 0.1 9.7e-07 28.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KUM61072.1 - 4.2e-08 34.0 0.0 6.4e-08 33.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KUM61072.1 - 7.9e-08 32.6 0.0 1.3e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KUM61072.1 - 7.9e-07 28.6 0.0 0.00022 20.6 0.0 2.2 1 1 0 1 1 1 1 Thymidylate kinase 4HBT PF03061.17 KUM61074.1 - 2.1e-07 30.9 0.1 3.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 KUM61075.1 - 8e-61 206.0 2.7 9.1e-61 205.8 1.9 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily RTA1 PF04479.8 KUM61076.1 - 3.9e-37 127.9 12.6 3.9e-37 127.9 8.7 1.7 1 1 1 2 2 2 1 RTA1 like protein Tetraspannin PF00335.15 KUM61076.1 - 0.59 9.3 16.2 0.016 14.5 4.3 2.4 1 1 1 2 2 2 0 Tetraspanin family DUF3098 PF11297.3 KUM61076.1 - 4.1 7.1 10.9 0.06 13.0 1.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3098) FMN_dh PF01070.13 KUM61077.1 - 2.6e-116 388.4 0.0 5.4e-116 387.3 0.0 1.5 1 1 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KUM61077.1 - 4.9e-07 28.9 0.1 9.2e-07 28.0 0.0 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KUM61077.1 - 5e-05 22.3 0.0 9.2e-05 21.5 0.0 1.4 1 1 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 KUM61077.1 - 0.00032 20.0 0.0 0.034 13.4 0.0 2.5 1 1 0 2 2 2 1 Histidine biosynthesis protein NMO PF03060.10 KUM61077.1 - 0.0023 17.1 0.0 0.0044 16.2 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.16 KUM61077.1 - 0.0028 16.6 0.1 0.0086 15.0 0.0 1.8 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase ThiG PF05690.9 KUM61077.1 - 0.006 15.6 0.0 0.24 10.4 0.0 2.4 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG bZIP_1 PF00170.16 KUM61078.1 - 0.0011 18.8 1.3 0.0024 17.7 0.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor DHDPS PF00701.17 KUM61079.1 - 6.2e-64 215.3 0.0 7e-64 215.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Fungal_trans_2 PF11951.3 KUM61080.1 - 6.5e-46 156.6 3.3 9.4e-46 156.1 2.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_3 PF07859.8 KUM61081.1 - 1.5e-49 168.4 0.0 1.9e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KUM61081.1 - 0.0002 21.3 0.0 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM61081.1 - 0.0002 21.1 0.0 0.00027 20.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KUM61081.1 - 0.00038 19.2 0.3 0.0009 18.0 0.2 1.7 1 1 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 KUM61081.1 - 0.0019 16.9 0.0 0.0025 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_1 PF00561.15 KUM61081.1 - 0.0029 17.1 0.0 0.0038 16.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 KUM61081.1 - 0.0091 14.5 0.0 0.013 13.9 0.0 1.2 1 0 0 1 1 1 1 Ndr family Thioesterase PF00975.15 KUM61081.1 - 0.011 16.0 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Aldedh PF00171.17 KUM61082.1 - 1.5e-184 613.7 0.2 1.7e-184 613.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TRI5 PF06330.6 KUM61083.1 - 5.2e-82 275.4 0.2 6.7e-82 275.1 0.2 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) DLH PF01738.13 KUM61084.1 - 5.5e-18 65.0 0.0 1e-17 64.1 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KUM61084.1 - 1.5e-07 31.2 0.0 2.1e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KUM61084.1 - 1.2e-05 25.2 0.0 0.0002 21.3 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 KUM61084.1 - 0.05 13.3 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal MUG113 PF13455.1 KUM61085.1 - 9.7e-36 122.0 0.5 1.7e-35 121.3 0.4 1.4 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 KUM61085.1 - 1.5e-25 89.4 0.1 4.4e-25 87.9 0.1 1.8 1 0 0 1 1 1 1 T5orf172 domain EB PF01683.13 KUM61086.1 - 0.00048 20.1 52.3 0.0066 16.4 3.3 5.1 1 1 4 5 5 5 3 EB module Toxin_12 PF07740.7 KUM61086.1 - 0.033 14.6 1.5 0.033 14.6 1.0 5.4 5 0 0 5 5 5 0 Ion channel inhibitory toxin DUF2199 PF09965.4 KUM61087.1 - 0.046 13.5 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) MFS_1 PF07690.11 KUM61089.1 - 1.2e-44 152.4 70.5 1.2e-37 129.4 30.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox_2 PF07992.9 KUM61090.1 - 6.9e-13 48.9 0.0 1e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KUM61090.1 - 6.2e-05 22.0 0.5 0.0001 21.3 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KUM61090.1 - 8.6e-05 22.4 0.5 0.00025 21.0 0.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KUM61090.1 - 0.00025 19.6 0.1 0.0017 16.9 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 KUM61090.1 - 0.00026 21.1 0.3 0.06 13.4 0.1 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KUM61090.1 - 0.00032 19.7 0.5 0.00099 18.0 0.4 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KUM61090.1 - 0.00068 19.4 0.2 0.24 11.1 0.1 2.2 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.17 KUM61090.1 - 0.0014 17.6 1.4 0.029 13.2 0.6 2.1 1 1 1 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KUM61090.1 - 0.0026 16.8 0.3 0.004 16.2 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain K_oxygenase PF13434.1 KUM61090.1 - 0.0029 16.5 0.1 0.93 8.3 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 KUM61090.1 - 0.011 14.7 0.1 0.014 14.4 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 KUM61090.1 - 0.012 14.7 0.0 0.025 13.6 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 KUM61090.1 - 0.17 10.8 0.2 0.24 10.2 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.9 KUM61090.1 - 0.21 10.1 0.1 0.31 9.6 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase TB2_DP1_HVA22 PF03134.14 KUM61091.1 - 1.2e-28 98.6 5.9 1.8e-28 98.0 4.1 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family NRDE PF05742.7 KUM61092.1 - 1.8e-44 152.0 0.0 4.9e-44 150.6 0.0 1.6 1 1 0 1 1 1 1 NRDE protein Usp PF00582.21 KUM61093.1 - 1.1e-20 74.2 1.5 3.3e-20 72.7 0.1 2.4 3 1 0 3 3 3 1 Universal stress protein family MIF4G PF02854.14 KUM61094.1 - 2.1e-51 174.3 0.0 3e-51 173.8 0.0 1.2 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 KUM61094.1 - 3.5e-19 68.4 0.5 9.6e-19 67.0 0.3 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Cellulase PF00150.13 KUM61095.1 - 1.3e-55 188.6 2.0 1.9e-55 188.0 1.4 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KUM61095.1 - 5.7e-14 51.4 9.9 5.7e-14 51.4 6.8 1.9 2 0 0 2 2 2 1 Fungal cellulose binding domain TFIIA PF03153.8 KUM61095.1 - 3.9 7.2 5.8 6 6.6 4.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit p450 PF00067.17 KUM61096.1 - 2.9e-57 194.2 0.0 3.9e-57 193.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L7Ae PF01248.21 KUM61098.1 - 4.3e-26 90.2 0.0 5.2e-26 89.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KUM61098.1 - 0.00011 22.1 0.0 0.00011 22.0 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 BPL_N PF09825.4 KUM61099.1 - 4.1e-138 460.1 0.0 5.1e-138 459.8 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 KUM61099.1 - 5.1e-20 71.7 0.0 1.2e-19 70.5 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family CHCH PF06747.8 KUM61100.1 - 3e-07 30.1 9.2 4.2e-07 29.7 6.4 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 KUM61100.1 - 0.008 15.9 7.5 0.042 13.6 5.2 1.9 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 KUM61100.1 - 0.023 14.7 4.4 0.031 14.2 3.0 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Ndufs5 PF10200.4 KUM61100.1 - 0.028 14.3 4.5 0.039 13.9 3.1 1.3 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Pet191_N PF10203.4 KUM61100.1 - 0.11 12.5 4.4 0.15 12.1 3.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Toxin_25 PF08095.6 KUM61100.1 - 0.12 12.1 3.7 0.16 11.7 0.1 2.4 2 0 0 2 2 2 0 Hefutoxin family Mgm101p PF06420.7 KUM61101.1 - 7.5e-90 298.7 0.0 9.5e-90 298.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Med3 PF11593.3 KUM61101.1 - 8.1 5.5 10.6 11 5.1 7.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MS_channel PF00924.13 KUM61102.1 - 1.5e-20 73.4 0.6 2.7e-20 72.5 0.4 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 KUM61102.1 - 0.0005 19.1 0.3 0.0015 17.6 0.2 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KUM61102.1 - 0.0038 16.9 0.2 0.02 14.7 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 KUM61102.1 - 0.0039 17.3 0.2 0.011 15.8 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KUM61102.1 - 0.061 12.6 0.3 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 EF hand PhyH PF05721.8 KUM61103.1 - 3.4e-26 92.5 0.1 5.3e-26 91.9 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) NACHT PF05729.7 KUM61104.1 - 0.027 14.1 0.1 0.091 12.4 0.0 1.9 1 0 0 1 1 1 0 NACHT domain PRTP PF01366.13 KUM61104.1 - 0.17 9.8 0.0 0.34 8.8 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Filament PF00038.16 KUM61105.1 - 0.00015 21.3 154.0 0.024 14.1 24.7 8.6 2 1 7 10 10 10 6 Intermediate filament protein Pox_A_type_inc PF04508.7 KUM61105.1 - 0.00047 19.7 10.4 0.3 10.9 0.0 7.2 7 0 0 7 7 7 2 Viral A-type inclusion protein repeat Fib_alpha PF08702.5 KUM61105.1 - 0.0019 18.3 0.7 0.0019 18.3 0.5 10.2 2 1 10 12 12 12 1 Fibrinogen alpha/beta chain family NmrA PF05368.8 KUM61107.1 - 4.8e-22 78.3 0.0 6.4e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KUM61107.1 - 6.4e-18 65.4 0.1 9.4e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KUM61107.1 - 7.5e-05 22.2 0.1 0.00036 20.0 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KUM61107.1 - 0.0013 17.8 0.1 0.0019 17.2 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 KUM61107.1 - 0.014 15.3 0.1 0.059 13.2 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 KUM61107.1 - 0.016 14.1 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein 3Beta_HSD PF01073.14 KUM61107.1 - 0.041 12.5 0.0 0.073 11.7 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KUM61107.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Transket_pyr PF02779.19 KUM61108.1 - 1e-43 148.8 0.1 2.2e-43 147.8 0.0 1.5 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KUM61108.1 - 2.8e-31 108.0 0.0 1.2e-30 105.9 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain DUF572 PF04502.8 KUM61109.1 - 1.5e-54 185.4 0.2 1.7e-54 185.2 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) IncA PF04156.9 KUM61109.1 - 8 6.0 5.7 12 5.4 4.0 1.2 1 0 0 1 1 1 0 IncA protein IBR PF01485.16 KUM61110.1 - 7.4e-11 41.7 44.2 3e-06 26.9 8.4 3.7 3 1 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 KUM61110.1 - 0.00026 20.7 7.5 0.00026 20.7 5.2 3.7 2 1 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 KUM61110.1 - 0.002 17.8 8.3 0.002 17.8 5.8 4.2 3 2 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KUM61110.1 - 0.016 15.2 7.2 0.016 15.2 5.0 4.1 3 2 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) PTPA PF03095.10 KUM61112.1 - 6.4e-113 376.8 0.0 7.5e-113 376.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein PRA1 PF03208.14 KUM61114.1 - 5 6.4 10.9 37 3.6 7.5 2.0 1 1 0 1 1 1 0 PRA1 family protein DUF4131 PF13567.1 KUM61114.1 - 5.4 6.3 6.6 7.8 5.8 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Peptidase_M3 PF01432.15 KUM61115.1 - 2.8e-116 389.2 0.0 4.2e-116 388.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 ApoO PF09769.4 KUM61116.1 - 1.5e-46 158.0 0.0 4.1e-46 156.5 0.0 1.7 2 0 0 2 2 2 1 Apolipoprotein O GRASP55_65 PF04495.9 KUM61117.1 - 1.9e-41 141.3 0.0 1.4e-40 138.5 0.0 1.9 1 1 1 2 2 2 1 GRASP55/65 PDZ-like domain Methyltransf_15 PF09445.5 KUM61118.1 - 3.3e-50 169.8 0.0 4.2e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.11 KUM61118.1 - 1.8e-10 40.7 0.0 2.4e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 KUM61118.1 - 9.2e-10 38.5 0.0 1.3e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 KUM61118.1 - 4.1e-09 36.2 0.0 5.2e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 KUM61118.1 - 3.3e-07 30.8 0.0 4.1e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KUM61118.1 - 6.7e-07 28.8 0.0 9.2e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 KUM61118.1 - 1.1e-06 28.2 0.0 1.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 KUM61118.1 - 0.00032 19.8 0.0 0.00043 19.4 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_3 PF01596.12 KUM61118.1 - 0.019 14.0 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase MTS PF05175.9 KUM61118.1 - 0.019 14.3 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain OpuAC PF04069.7 KUM61118.1 - 0.059 12.7 0.1 0.14 11.4 0.0 1.6 2 0 0 2 2 2 0 Substrate binding domain of ABC-type glycine betaine transport system Methyltransf_5 PF01795.14 KUM61118.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family PrmA PF06325.8 KUM61118.1 - 0.15 11.1 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) zf-RING_3 PF14369.1 KUM61119.1 - 9.5e-06 25.5 1.3 1.7e-05 24.6 0.9 1.5 1 0 0 1 1 1 1 zinc-finger zf-TFIIB PF13453.1 KUM61119.1 - 0.00041 19.4 1.6 0.016 14.3 0.1 2.6 1 1 1 2 2 2 2 Transcription factor zinc-finger zf-ribbon_3 PF13248.1 KUM61119.1 - 0.0056 15.8 0.5 0.0093 15.1 0.3 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zf-C3HC4_3 PF13920.1 KUM61119.1 - 0.0097 15.5 0.2 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) HypA PF01155.14 KUM61119.1 - 0.029 14.0 0.3 0.045 13.4 0.2 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 KUM61119.1 - 0.032 14.0 0.5 0.057 13.2 0.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon IMS PF00817.15 KUM61121.1 - 1.2e-42 145.2 0.0 2.1e-42 144.4 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KUM61121.1 - 4.5e-19 68.6 0.0 1e-18 67.4 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 KUM61121.1 - 5.8e-15 55.1 12.0 2.9e-08 33.5 0.4 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4414) BRCT PF00533.21 KUM61121.1 - 4e-06 26.8 0.0 1.1e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.3 KUM61121.1 - 2.7e-05 23.9 0.0 0.0001 22.0 0.0 2.1 1 0 0 1 1 1 1 IMS family HHH motif HHH_5 PF14520.1 KUM61121.1 - 0.00019 21.5 0.1 0.0014 18.7 0.0 2.4 1 1 1 2 2 2 1 Helix-hairpin-helix domain PTCB-BRCT PF12738.2 KUM61121.1 - 0.0012 18.6 0.0 0.0043 16.8 0.0 2.0 2 0 0 2 2 2 1 twin BRCT domain DUF1805 PF08827.6 KUM61121.1 - 0.15 11.8 0.0 0.46 10.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) MgtE_N PF03448.12 KUM61121.1 - 0.29 11.4 2.7 14 6.0 0.2 3.9 4 0 0 4 4 4 0 MgtE intracellular N domain FKBP_C PF00254.23 KUM61122.1 - 2.1e-31 107.7 0.0 9e-31 105.7 0.0 2.1 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Zip PF02535.17 KUM61123.1 - 7.6e-52 176.2 1.0 9.8e-52 175.9 0.7 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter HC2 PF07382.6 KUM61124.1 - 0.016 15.1 70.5 0.018 14.9 48.1 1.5 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 DUF3184 PF11380.3 KUM61124.1 - 0.23 9.3 6.1 0.33 8.8 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3184) Fungal_trans PF04082.13 KUM61125.1 - 2.7e-34 118.2 0.0 4.6e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM61125.1 - 2.6e-08 33.6 8.7 4.7e-08 32.7 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HNH_2 PF13391.1 KUM61126.1 - 6.5e-15 54.6 0.0 1.1e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease DENN PF02141.16 KUM61127.1 - 0.09 12.4 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 DENN (AEX-3) domain Ketoacyl-synt_C PF02801.17 KUM61128.1 - 0.042 13.6 0.0 0.058 13.2 0.0 1.2 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain FAD_binding_3 PF01494.14 KUM61129.1 - 3.2e-22 79.0 0.5 7.7e-22 77.8 0.3 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KUM61129.1 - 2.7e-10 39.7 2.8 0.00016 20.7 1.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KUM61129.1 - 1.6e-05 23.9 4.9 3.1e-05 23.0 3.1 1.6 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 KUM61129.1 - 5.7e-05 22.1 0.3 0.00016 20.6 0.2 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KUM61129.1 - 0.00012 22.0 1.4 0.00027 20.8 1.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KUM61129.1 - 0.00019 21.7 0.4 0.0019 18.5 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KUM61129.1 - 0.00067 19.5 1.2 0.0017 18.2 0.8 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KUM61129.1 - 0.00075 19.6 0.1 0.0017 18.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KUM61129.1 - 0.0015 17.0 3.0 0.0041 15.6 2.1 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 KUM61129.1 - 0.002 17.3 0.3 0.003 16.7 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KUM61129.1 - 0.0049 16.0 2.6 0.023 13.8 1.6 2.0 1 1 0 1 1 1 1 Thi4 family GIDA PF01134.17 KUM61129.1 - 0.021 13.7 3.0 0.036 12.9 2.0 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 KUM61129.1 - 0.03 12.9 0.9 0.12 10.9 0.2 2.1 2 1 0 3 3 3 0 Tryptophan halogenase AlaDh_PNT_C PF01262.16 KUM61129.1 - 0.13 11.7 0.9 0.27 10.8 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Arginosuc_synth PF00764.14 KUM61130.1 - 8.3e-157 522.1 0.0 9.5e-157 521.9 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 KUM61130.1 - 0.00051 19.6 0.0 0.00074 19.0 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 KUM61130.1 - 0.0072 15.6 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 KUM61130.1 - 0.022 13.3 0.0 0.032 12.7 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Pkinase PF00069.20 KUM61131.1 - 3.2e-48 164.1 0.3 6.3e-25 87.7 0.0 3.2 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 KUM61131.1 - 1.7e-21 76.4 0.0 4.8e-12 45.4 0.0 3.2 2 1 1 3 3 3 3 Protein tyrosine kinase APH PF01636.18 KUM61131.1 - 0.00048 19.9 0.4 0.0011 18.7 0.3 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KUM61131.1 - 0.19 10.4 0.0 0.56 8.9 0.0 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase DUF3591 PF12157.3 KUM61132.1 - 2.5e-191 636.0 0.1 3.3e-191 635.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 KUM61132.1 - 0.0041 16.7 1.2 0.0088 15.6 0.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KUM61132.1 - 0.015 15.1 0.9 0.025 14.4 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle p450 PF00067.17 KUM61133.1 - 2.4e-72 243.9 0.0 2.8e-72 243.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 BAR PF03114.13 KUM61133.1 - 0.0057 16.1 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 BAR domain Ion_trans_2 PF07885.11 KUM61133.1 - 0.064 12.9 1.0 0.15 11.7 0.7 1.6 1 0 0 1 1 1 0 Ion channel DUF3684 PF12449.3 KUM61133.1 - 0.24 8.9 0.1 0.34 8.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) TCO89 PF10452.4 KUM61134.1 - 0.025 13.4 21.8 2 7.1 0.0 3.2 2 1 0 2 2 2 0 TORC1 subunit TCO89 NAD_binding_10 PF13460.1 KUM61135.1 - 0.0007 19.6 0.2 0.0016 18.4 0.2 1.6 1 1 0 1 1 1 1 NADH(P)-binding FA_hydroxylase PF04116.8 KUM61135.1 - 0.001 19.4 0.9 0.0024 18.2 0.6 1.7 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily FA_desaturase PF00487.19 KUM61135.1 - 0.014 14.8 1.9 0.035 13.5 1.3 1.6 1 0 0 1 1 1 0 Fatty acid desaturase 3Beta_HSD PF01073.14 KUM61135.1 - 0.017 13.8 0.0 0.023 13.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KUM61135.1 - 0.021 14.2 0.1 0.056 12.8 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KUM61135.1 - 0.066 13.1 0.2 0.12 12.3 0.1 1.4 1 1 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 KUM61135.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Pico_P2A PF00947.14 KUM61135.1 - 0.13 12.0 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Picornavirus core protein 2A Glyco_transf_28 PF03033.15 KUM61136.1 - 4.1e-23 81.6 0.0 1.2e-22 80.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KUM61136.1 - 1.4e-06 27.1 0.0 2.2e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Fungal_trans_2 PF11951.3 KUM61137.1 - 1.6e-12 46.7 0.1 3.5e-11 42.3 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM61137.1 - 3.5e-09 36.4 8.9 8.1e-09 35.2 6.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CAP59_mtransfer PF11735.3 KUM61137.1 - 0.14 11.3 0.3 0.49 9.5 0.2 1.8 1 1 0 1 1 1 0 Cryptococcal mannosyltransferase 1 Pkinase PF00069.20 KUM61138.1 - 0.011 14.9 0.0 0.011 14.9 0.0 1.0 1 0 0 1 1 1 0 Protein kinase domain MARVEL PF01284.18 KUM61139.1 - 3.8e-09 36.5 12.9 6.2e-09 35.8 9.0 1.3 1 0 0 1 1 1 1 Membrane-associating domain MpPF26 PF07666.6 KUM61139.1 - 0.055 13.3 0.8 0.13 12.1 0.3 1.7 1 1 1 2 2 2 0 M penetrans paralogue family 26 RTA1 PF04479.8 KUM61140.1 - 6.2e-41 140.3 4.8 8e-41 139.9 3.3 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF4234 PF14018.1 KUM61140.1 - 0.042 13.6 3.1 9.6 6.0 0.0 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4234) NAGidase PF07555.8 KUM61140.1 - 0.11 11.3 0.2 0.15 10.9 0.1 1.1 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase DUF4131 PF13567.1 KUM61140.1 - 1.6 8.1 10.1 3.1 7.1 2.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2207 PF09972.4 KUM61140.1 - 3.6 6.0 5.0 6 5.3 3.5 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Pkinase PF00069.20 KUM61141.1 - 2.2e-15 56.5 0.0 3e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM61141.1 - 0.0005 19.2 0.1 0.018 14.1 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.17 KUM61141.1 - 0.084 12.2 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 KUM61142.1 - 0.039 13.0 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Med13_C PF06333.7 KUM61143.1 - 1.9e-107 359.4 0.1 3.1e-107 358.7 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 KUM61143.1 - 8.2e-74 248.6 0.0 1.3e-73 248.0 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal Rsm1 PF08600.5 KUM61143.1 - 0.087 12.6 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 Rsm1-like NUC153 PF08159.7 KUM61144.1 - 3.3e-13 48.9 0.0 9.7e-13 47.4 0.0 1.9 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 KUM61144.1 - 0.0034 17.2 0.0 1.1 9.2 0.0 4.1 5 0 0 5 5 5 1 WD domain, G-beta repeat 6PGD PF00393.14 KUM61145.1 - 8.7e-135 448.5 0.0 1e-134 448.2 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KUM61145.1 - 8.9e-52 175.2 0.0 1.3e-51 174.7 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KUM61145.1 - 0.033 14.2 0.0 0.079 13.0 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PGK PF00162.14 KUM61145.1 - 0.062 11.8 0.0 0.092 11.2 0.0 1.1 1 0 0 1 1 1 0 Phosphoglycerate kinase RRM_1 PF00076.17 KUM61146.1 - 5.5e-17 61.1 0.0 9e-17 60.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM61146.1 - 1.3e-09 37.8 0.0 2.5e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM61146.1 - 0.054 13.3 0.0 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATG13 PF10033.4 KUM61147.1 - 1.4e-78 263.5 0.0 2.3e-78 262.8 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 LIP PF03583.9 KUM61150.1 - 2.4e-66 223.8 0.4 3.8e-66 223.2 0.3 1.3 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 KUM61150.1 - 4.7e-06 26.6 0.0 8.2e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM61150.1 - 1.5e-05 24.7 0.0 3.2e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KUM61150.1 - 3e-05 23.3 0.0 0.21 10.8 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KUM61150.1 - 0.0035 16.7 0.0 0.012 15.0 0.0 1.8 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.13 KUM61150.1 - 0.072 12.3 0.2 0.24 10.6 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family RCC1 PF00415.13 KUM61151.1 - 3.3e-24 84.8 0.4 1.6e-06 28.2 0.0 5.8 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 KUM61151.1 - 2.6e-14 53.1 0.0 5.7e-11 42.3 0.1 2.5 2 0 0 2 2 2 2 BTB/POZ domain RCC1_2 PF13540.1 KUM61151.1 - 5.8e-11 41.7 3.5 3.9e-07 29.5 0.1 3.0 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.1 KUM61151.1 - 9e-09 35.6 0.2 0.00048 20.5 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM61151.1 - 6.2e-05 22.8 0.3 0.46 10.8 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 KUM61151.1 - 0.00028 21.1 0.1 0.0054 17.0 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KUM61151.1 - 0.033 14.4 0.0 2.2 8.6 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Cyt-b5 PF00173.23 KUM61153.1 - 4.3e-25 87.3 0.0 5.5e-25 86.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain YqzH PF14164.1 KUM61153.1 - 0.02 14.8 0.2 0.034 14.0 0.1 1.4 1 0 0 1 1 1 0 YqzH-like protein KH_1 PF00013.24 KUM61154.1 - 8.4e-87 284.7 20.8 1.8e-11 43.4 0.2 12.9 13 0 0 13 13 13 9 KH domain KH_3 PF13014.1 KUM61154.1 - 1.1e-64 213.1 17.3 2.7e-09 36.4 0.8 12.4 13 0 0 13 13 13 10 KH domain SLS PF14611.1 KUM61154.1 - 1.8e-13 50.4 1.6 0.18 11.2 0.0 7.3 6 2 2 8 8 8 3 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 KUM61154.1 - 8e-12 44.5 23.1 0.003 17.0 0.2 7.2 6 1 1 7 7 7 6 KH domain BMC PF00936.14 KUM61154.1 - 0.00047 19.7 4.2 8.5 6.1 0.1 6.0 8 0 0 8 8 8 2 BMC domain KH_5 PF13184.1 KUM61154.1 - 0.00073 19.2 6.6 21 5.0 0.1 7.1 7 0 0 7 7 7 0 NusA-like KH domain KH_4 PF13083.1 KUM61154.1 - 0.0061 16.1 7.6 5.4 6.7 0.0 5.1 5 0 0 5 5 5 2 KH domain Acylphosphatase PF00708.13 KUM61154.1 - 0.053 13.6 0.5 1.7 8.8 0.1 3.4 2 0 0 2 2 2 0 Acylphosphatase DUF4097 PF13349.1 KUM61154.1 - 0.09 12.3 0.1 2.1 7.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4097) VHS PF00790.14 KUM61155.1 - 6.5e-40 136.0 0.8 6.5e-39 132.7 0.0 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 KUM61155.1 - 2.3e-16 59.4 2.4 3.7e-16 58.7 1.6 1.3 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 KUM61155.1 - 0.00077 18.8 16.9 0.0062 16.0 1.4 3.6 3 0 0 3 3 3 2 Ubiquitin interaction motif zf-DHHC PF01529.15 KUM61155.1 - 0.018 14.4 0.3 0.038 13.3 0.2 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase FYVE_2 PF02318.11 KUM61155.1 - 0.05 13.4 0.3 0.1 12.5 0.2 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger UCH PF00443.24 KUM61156.1 - 1.2e-55 188.5 0.0 2e-55 187.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KUM61156.1 - 3.2e-29 102.3 0.0 5.4e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.6 KUM61156.1 - 1.7e-06 27.9 0.2 5.2e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 USP8 dimerisation domain Rhodanese PF00581.15 KUM61156.1 - 0.01 16.1 0.0 0.027 14.8 0.0 1.8 1 0 0 1 1 1 0 Rhodanese-like domain Sec10 PF07393.6 KUM61157.1 - 1.3e-230 767.3 0.0 1.6e-230 767.1 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 Apolipoprotein PF01442.13 KUM61157.1 - 0.031 13.7 6.0 0.92 8.9 1.0 3.5 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Tropomyosin PF00261.15 KUM61157.1 - 0.044 12.8 0.1 0.13 11.3 0.1 1.7 1 0 0 1 1 1 0 Tropomyosin Baculo_PEP_C PF04513.7 KUM61157.1 - 0.12 12.2 5.0 1.6 8.5 0.4 3.2 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlgN PF05130.7 KUM61157.1 - 0.24 11.6 9.7 7.4 6.8 0.0 4.0 4 0 0 4 4 4 0 FlgN protein Prenyltransf PF01255.14 KUM61158.1 - 0.0082 15.2 0.0 0.023 13.8 0.0 1.7 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase ELMO_CED12 PF04727.8 KUM61159.1 - 5.4e-46 156.2 0.1 1.1e-45 155.2 0.0 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 KUM61159.1 - 3.4e-05 23.6 0.2 0.00041 20.0 0.1 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3361) DUF1752 PF08550.5 KUM61160.1 - 3.7e-11 42.4 3.8 7.4e-11 41.4 2.6 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF3752 PF12572.3 KUM61161.1 - 1.7e-36 125.6 11.4 1.7e-36 125.6 7.9 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) Sigma70_ner PF04546.8 KUM61161.1 - 0.59 9.7 12.1 0.21 11.1 2.3 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Ribosomal_60s PF00428.14 KUM61161.1 - 8 6.9 7.2 2.3 8.6 0.5 2.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein Nucleoplasmin PF03066.10 KUM61161.1 - 9.1 5.7 10.3 0.5 9.8 2.8 2.0 2 0 0 2 2 2 0 Nucleoplasmin Peptidase_M75 PF09375.5 KUM61162.1 - 0.07 12.4 0.1 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Imelysin A_deaminase PF00962.17 KUM61163.1 - 5.2e-113 377.3 0.0 7.1e-113 376.8 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase SH3_9 PF14604.1 KUM61165.1 - 1.3e-26 91.8 5.6 1.2e-12 47.1 0.4 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KUM61165.1 - 2.1e-24 84.6 6.3 2.2e-12 46.1 0.4 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 KUM61165.1 - 4.8e-15 54.7 1.5 8.4e-07 28.3 0.1 2.9 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.15 KUM61165.1 - 1.5e-10 41.0 0.0 2.6e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Dynamin_M PF01031.15 KUM61166.1 - 5.6e-114 379.8 0.0 1e-113 379.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 KUM61166.1 - 6e-54 182.3 0.0 1.1e-53 181.4 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KUM61166.1 - 7e-31 105.9 0.6 7e-31 105.9 0.4 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KUM61166.1 - 0.00071 19.5 0.2 0.0046 16.8 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KUM61166.1 - 0.015 15.8 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein FeoB_N PF02421.13 KUM61166.1 - 0.025 13.8 0.1 1.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B UAA PF08449.6 KUM61167.1 - 4.4e-79 265.5 5.1 1e-78 264.3 3.5 1.5 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 KUM61167.1 - 7.4e-05 21.9 0.2 0.00017 20.7 0.2 1.5 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 KUM61167.1 - 0.00043 19.9 7.7 0.0025 17.4 5.3 2.3 1 1 0 1 1 1 1 Triose-phosphate Transporter family EmrE PF13536.1 KUM61167.1 - 0.026 14.7 19.4 0.17 12.0 0.8 3.8 2 1 1 3 3 3 0 Multidrug resistance efflux transporter EamA PF00892.15 KUM61167.1 - 0.11 12.4 22.3 0.084 12.9 3.5 3.7 3 1 1 4 4 4 0 EamA-like transporter family Rad17 PF03215.10 KUM61168.1 - 3.2e-57 194.4 0.0 4.5e-57 193.9 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 KUM61168.1 - 1.1e-05 25.5 0.0 2.2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KUM61168.1 - 0.00063 20.5 0.0 0.0017 19.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KUM61168.1 - 0.00078 19.1 0.2 0.0031 17.2 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA PF00004.24 KUM61168.1 - 0.00088 19.4 0.0 0.0023 18.1 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KUM61168.1 - 0.024 14.9 0.0 0.058 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KUM61168.1 - 0.025 14.1 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KUM61168.1 - 0.03 14.4 0.0 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 KUM61168.1 - 0.053 12.4 0.0 0.089 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 KUM61168.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.2 KUM61169.1 - 5.9e-39 132.3 0.4 4.9e-12 46.0 0.1 6.2 4 1 2 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KUM61169.1 - 5.5e-24 84.0 5.9 4.2e-05 23.9 0.0 9.0 6 2 3 10 10 10 5 Ankyrin repeats (many copies) Pkinase PF00069.20 KUM61169.1 - 2.5e-23 82.5 0.0 4e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank PF00023.25 KUM61169.1 - 4.1e-23 79.9 15.8 0.00026 20.6 0.0 11.6 11 1 0 11 11 11 4 Ankyrin repeat Ank_3 PF13606.1 KUM61169.1 - 2.4e-22 76.7 7.2 0.0015 18.6 0.1 10.2 11 0 0 11 11 11 5 Ankyrin repeat Ank_5 PF13857.1 KUM61169.1 - 1.2e-18 66.7 7.6 3.3e-05 23.9 0.0 8.1 5 3 3 8 8 8 4 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.12 KUM61169.1 - 1.2e-17 63.8 0.0 2e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ribonucleas_3_2 PF11469.3 KUM61169.1 - 0.15 12.3 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease III Kinase-like PF14531.1 KUM61169.1 - 0.18 10.6 0.0 0.33 9.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.6 KUM61169.1 - 0.47 9.1 0.0 0.72 8.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HeLo PF14479.1 KUM61171.1 - 7.6e-21 74.8 0.7 1.4e-20 74.0 0.5 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.12 KUM61171.1 - 0.00016 20.8 0.0 0.00059 18.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase DUF825 PF05695.7 KUM61171.1 - 0.016 12.6 0.3 0.022 12.2 0.2 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) Pkinase PF00069.20 KUM61171.1 - 0.019 14.1 0.0 0.038 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain Glyco_tranf_2_3 PF13641.1 KUM61172.1 - 4.2e-20 72.5 0.0 6.9e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KUM61172.1 - 3.7e-11 43.1 0.4 3.7e-11 43.1 0.3 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 KUM61172.1 - 0.00048 19.8 0.0 0.00083 19.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KUM61172.1 - 0.0017 17.6 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 DUF2207 PF09972.4 KUM61172.1 - 3.7 6.0 7.2 0.15 10.5 0.2 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) BNR PF02012.15 KUM61174.1 - 1.7e-07 30.0 27.1 1.2 9.2 0.2 10.3 10 0 0 10 10 10 4 BNR/Asp-box repeat Mo-co_dimer PF03404.11 KUM61174.1 - 0.00039 20.0 0.2 1.5 8.4 0.0 4.6 4 0 0 4 4 4 1 Mo-co oxidoreductase dimerisation domain DUF2167 PF09935.4 KUM61174.1 - 0.0071 15.2 0.3 0.025 13.4 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2167) Acyl_transf_3 PF01757.17 KUM61174.1 - 0.1 11.3 0.3 0.16 10.7 0.2 1.2 1 0 0 1 1 1 0 Acyltransferase family dCMP_cyt_deam_1 PF00383.17 KUM61175.1 - 3.2e-16 58.8 0.1 3.7e-16 58.6 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 KUM61175.1 - 3.6e-09 36.6 0.9 8.4e-08 32.2 0.1 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 KUM61175.1 - 7.9e-05 22.1 0.8 0.22 10.8 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases NmrA PF05368.8 KUM61176.1 - 3.1e-37 128.0 0.1 3.9e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KUM61176.1 - 1.1e-13 51.6 0.1 3.2e-13 50.0 0.0 1.7 1 1 1 2 2 2 1 NADH(P)-binding adh_short PF00106.20 KUM61176.1 - 8e-05 22.6 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KUM61176.1 - 0.00012 21.6 0.0 0.00028 20.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KUM61176.1 - 0.00015 21.4 0.0 0.00025 20.7 0.0 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 KUM61176.1 - 0.003 16.2 0.0 0.0046 15.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KUM61176.1 - 0.0097 14.8 0.1 0.049 12.5 0.0 1.9 1 1 1 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.19 KUM61176.1 - 0.022 15.0 0.0 0.06 13.6 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CmcI PF04989.7 KUM61176.1 - 0.056 12.7 0.0 0.13 11.5 0.0 1.5 2 0 0 2 2 2 0 Cephalosporin hydroxylase Polysacc_synt_2 PF02719.10 KUM61176.1 - 0.082 11.7 0.0 0.41 9.4 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Fungal_trans PF04082.13 KUM61177.1 - 9.8e-16 57.3 0.2 2.2e-15 56.2 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Mito_carr PF00153.22 KUM61178.1 - 1e-67 223.8 0.7 2.1e-22 78.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cgr1 PF03879.9 KUM61179.1 - 1.6e-37 127.9 21.8 1.8e-37 127.8 15.1 1.0 1 0 0 1 1 1 1 Cgr1 family 2OG-FeII_Oxy_4 PF13661.1 KUM61179.1 - 0.049 13.2 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Caudo_TAP PF02413.12 KUM61179.1 - 0.086 13.0 2.3 0.1 12.7 1.6 1.3 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein N2227 PF07942.7 KUM61179.1 - 0.19 10.6 1.6 0.23 10.3 1.1 1.2 1 0 0 1 1 1 0 N2227-like protein PRP1_N PF06424.7 KUM61179.1 - 0.43 10.9 8.3 0.52 10.6 5.7 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF2058 PF09831.4 KUM61179.1 - 1.8 8.4 13.0 2.2 8.1 9.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) OmpH PF03938.9 KUM61179.1 - 3.3 7.6 11.4 4.2 7.2 7.9 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DDHD PF02862.12 KUM61179.1 - 4.9 6.8 6.2 5.8 6.6 4.3 1.0 1 0 0 1 1 1 0 DDHD domain GAS PF13851.1 KUM61180.1 - 0.00029 20.1 2.3 0.00051 19.2 1.6 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 KUM61180.1 - 0.00082 17.9 0.9 0.0011 17.5 0.6 1.1 1 0 0 1 1 1 1 AAA domain BicD PF09730.4 KUM61180.1 - 0.0012 17.2 0.5 0.0018 16.7 0.3 1.3 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D Baculo_PEP_C PF04513.7 KUM61180.1 - 0.013 15.3 1.2 0.15 11.8 1.1 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 KUM61180.1 - 0.013 14.1 0.5 0.018 13.7 0.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein MscS_porin PF12795.2 KUM61180.1 - 0.018 14.3 1.2 0.018 14.3 0.8 2.2 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain DUF607 PF04678.8 KUM61180.1 - 0.028 14.3 0.7 0.086 12.7 0.5 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF607 MtrB PF05440.7 KUM61180.1 - 0.028 14.4 0.0 0.5 10.4 0.0 2.4 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B CENP-F_leu_zip PF10473.4 KUM61180.1 - 0.03 14.1 3.2 0.059 13.2 2.2 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EMP24_GP25L PF01105.19 KUM61180.1 - 0.031 14.0 0.7 0.05 13.3 0.5 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD AKNA PF12443.3 KUM61180.1 - 0.052 13.5 0.6 0.052 13.5 0.4 2.2 2 0 0 2 2 2 0 AT-hook-containing transcription factor MtrG PF04210.8 KUM61180.1 - 0.095 12.3 0.2 0.37 10.5 0.0 2.0 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Snapin_Pallidin PF14712.1 KUM61180.1 - 0.1 12.9 1.2 0.24 11.7 0.9 1.7 1 0 0 1 1 1 0 Snapin/Pallidin WEMBL PF05701.6 KUM61180.1 - 0.17 10.3 4.0 0.22 9.9 2.8 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light BLOC1_2 PF10046.4 KUM61180.1 - 0.27 11.3 1.3 0.82 9.8 0.7 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin PF00804.20 KUM61180.1 - 1.2 9.3 5.6 8.3 6.6 3.9 2.3 1 1 0 1 1 1 0 Syntaxin SUI1 PF01253.17 KUM61181.1 - 6.2e-21 73.9 0.8 1.1e-20 73.2 0.5 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 Rotamase_2 PF13145.1 KUM61181.1 - 0.074 13.6 3.0 0.12 13.0 2.1 1.3 1 0 0 1 1 1 0 PPIC-type PPIASE domain TRSP PF12500.3 KUM61181.1 - 0.078 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 TRSP domain C terminus to PRTase_2 HK97-gp10_like PF04883.7 KUM61181.1 - 4.2 8.3 7.4 6.7 7.7 4.4 1.8 1 1 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component Cytochrom_C1 PF02167.10 KUM61182.1 - 1.4e-78 263.5 0.0 1.8e-78 263.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 KUM61182.1 - 0.0057 16.7 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 KUM61182.1 - 0.068 14.0 0.2 0.36 11.6 0.0 2.4 3 0 0 3 3 3 0 Cytochrome c hDGE_amylase PF14701.1 KUM61183.1 - 1.3e-181 604.1 0.0 1.6e-181 603.8 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 KUM61183.1 - 6.8e-112 373.8 0.0 1.3e-111 372.9 0.0 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 KUM61183.1 - 9.2e-89 297.0 0.0 1.3e-88 296.5 0.0 1.2 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 KUM61183.1 - 2.8e-26 91.1 0.0 6.1e-26 90.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 KUM61183.1 - 2.3e-05 23.9 0.2 0.0021 17.5 0.1 2.4 2 0 0 2 2 2 1 Alpha amylase, catalytic domain NAD_Gly3P_dh_N PF01210.18 KUM61184.1 - 4e-47 159.8 0.3 7e-47 159.0 0.1 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 KUM61184.1 - 1.6e-41 141.5 0.1 2.3e-41 140.9 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F-box PF00646.28 KUM61185.1 - 6.4e-07 28.8 0.1 2e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KUM61185.1 - 2.6e-06 27.0 1.3 2.6e-06 27.0 0.9 2.4 2 0 0 2 2 2 1 F-box-like TP6A_N PF04406.9 KUM61185.1 - 0.12 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Type IIB DNA topoisomerase Sec10 PF07393.6 KUM61186.1 - 2.2e-181 604.6 3.0 2.7e-181 604.3 2.1 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 KUM61186.1 - 2.7e-05 23.7 0.0 6.6e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KUM61186.1 - 0.0013 18.3 0.0 0.003 17.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain Brix PF04427.13 KUM61187.1 - 1.2e-29 103.3 0.0 1.5e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Brix domain F-box-like PF12937.2 KUM61188.1 - 1.7e-05 24.4 2.1 0.00014 21.5 1.3 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KUM61188.1 - 0.0031 17.1 4.3 0.011 15.3 3.0 2.0 1 0 0 1 1 1 1 F-box domain DUF1838 PF08894.6 KUM61188.1 - 0.028 13.6 0.0 0.046 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1838) PfkB PF00294.19 KUM61189.1 - 3.1e-17 62.6 0.0 1.2e-16 60.7 0.0 1.8 1 1 0 1 1 1 1 pfkB family carbohydrate kinase SLX9 PF15341.1 KUM61190.1 - 6.5e-34 116.9 10.9 8.2e-34 116.6 7.6 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Neugrin PF06413.6 KUM61190.1 - 0.0028 17.5 1.9 0.0035 17.1 1.3 1.2 1 0 0 1 1 1 1 Neugrin Peptidase_A2E PF12382.3 KUM61190.1 - 0.049 13.4 0.2 0.074 12.8 0.1 1.2 1 0 0 1 1 1 0 Retrotransposon peptidase DUF2894 PF11445.3 KUM61190.1 - 0.053 13.7 6.1 0.068 13.4 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) F-box-like PF12937.2 KUM61191.1 - 1.2e-06 28.1 0.1 3.6e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KUM61191.1 - 0.016 14.8 0.1 0.073 12.7 0.0 2.1 1 0 0 1 1 1 0 F-box domain DUF221 PF02714.10 KUM61192.1 - 8.3e-98 327.2 20.8 2.2e-97 325.8 14.4 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KUM61192.1 - 6.5e-44 149.2 0.3 6.5e-44 149.2 0.2 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KUM61192.1 - 8.1e-23 80.7 0.2 1.3e-22 80.0 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 KUM61192.1 - 0.013 15.4 0.0 2.5 8.1 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2200 PF09966.4 KUM61192.1 - 0.15 11.9 0.2 0.32 10.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2200) DAHP_synth_1 PF00793.15 KUM61193.1 - 1.5e-98 328.8 0.0 1.8e-98 328.5 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family AIG2_2 PF13772.1 KUM61194.1 - 0.00029 20.9 0.1 0.0041 17.2 0.0 2.6 3 0 0 3 3 3 1 AIG2-like family PsbJ PF01788.12 KUM61194.1 - 0.053 13.0 0.1 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 PsbJ DUF837 PF05769.6 KUM61195.1 - 0.0087 15.6 1.8 0.014 14.9 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF837) AAA_2 PF07724.9 KUM61196.1 - 2.1e-36 125.3 0.0 2.3e-35 122.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KUM61196.1 - 1.3e-14 54.5 0.0 3.1e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KUM61196.1 - 2.8e-07 30.3 0.0 7.3e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 KUM61196.1 - 2.6e-06 27.1 0.0 6.3e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KUM61196.1 - 0.00015 21.2 0.0 0.038 13.4 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 KUM61196.1 - 0.00022 20.4 0.1 0.012 14.7 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 KUM61196.1 - 0.00043 20.4 0.3 0.015 15.4 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KUM61196.1 - 0.0011 19.8 0.2 0.003 18.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 KUM61196.1 - 0.0011 18.4 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 KUM61196.1 - 0.0011 18.0 0.1 0.028 13.4 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 KUM61196.1 - 0.0016 18.0 0.0 0.0037 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KUM61196.1 - 0.0018 18.2 3.1 0.0057 16.6 0.1 2.6 1 1 2 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 KUM61196.1 - 0.024 14.0 0.5 0.098 12.0 0.1 2.1 2 1 1 3 3 3 0 AAA domain AAA_14 PF13173.1 KUM61196.1 - 0.026 14.4 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KUM61196.1 - 0.039 13.6 0.3 0.62 9.6 0.2 2.3 1 1 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 KUM61196.1 - 0.045 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DEAD PF00270.24 KUM61196.1 - 0.072 12.5 0.1 1.4 8.3 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase Sigma54_activ_2 PF14532.1 KUM61196.1 - 0.079 13.0 0.1 0.37 10.8 0.0 2.1 2 1 0 2 2 1 0 Sigma-54 interaction domain AAA_29 PF13555.1 KUM61196.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 KUM61196.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 KUM61196.1 - 0.16 11.8 1.8 0.4 10.5 0.0 2.4 3 0 0 3 3 2 0 AAA domain CAP PF00188.21 KUM61197.1 - 6.4e-21 75.1 5.8 7.5e-21 74.8 2.9 1.9 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Pex14_N PF04695.8 KUM61197.1 - 0.041 13.9 1.0 0.074 13.1 0.7 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF2A PF08662.6 KUM61198.1 - 2.3e-39 135.1 7.4 3e-36 124.9 3.6 4.0 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_6 PF14259.1 KUM61198.1 - 4.1e-06 26.6 0.0 8.5e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM61198.1 - 5.3e-06 26.1 0.0 1.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KUM61198.1 - 6.5e-06 25.6 0.0 1.3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KUM61198.1 - 0.0055 16.5 0.1 1.5 8.8 0.0 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat WD40 PF00400.27 KUM61199.1 - 3.3e-84 274.0 18.1 5.6e-14 51.4 0.0 8.5 8 1 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 KUM61199.1 - 1.5e-09 37.8 0.5 0.0019 17.9 0.0 3.8 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KUM61199.1 - 1.9e-07 29.6 7.5 0.11 10.5 0.0 5.3 2 2 4 6 6 6 3 Nucleoporin Nup120/160 NLE PF08154.7 KUM61199.1 - 2.8e-06 27.2 0.0 5.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain FAD_binding_9 PF08021.6 KUM61199.1 - 0.016 15.1 0.0 0.084 12.8 0.0 2.2 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Rav1p_C PF12234.3 KUM61199.1 - 0.017 13.3 0.0 0.78 7.8 0.0 2.4 1 1 1 2 2 2 0 RAVE protein 1 C terminal Velvet PF11754.3 KUM61202.1 - 2.8e-79 265.4 0.0 3.3e-79 265.2 0.0 1.0 1 0 0 1 1 1 1 Velvet factor SWIB PF02201.13 KUM61203.1 - 2.9e-25 87.7 0.1 9.6e-25 86.0 0.0 1.9 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.6 KUM61203.1 - 2.1e-14 52.9 0.7 4.4e-14 52.0 0.5 1.5 1 0 0 1 1 1 1 DEK C terminal domain DUF3235 PF11574.3 KUM61203.1 - 0.3 11.3 4.9 0.34 11.1 2.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3235) DUF3275 PF11679.3 KUM61203.1 - 0.39 10.3 8.6 0.11 12.1 3.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3275) zf-C3HC4_3 PF13920.1 KUM61204.1 - 1.7e-05 24.4 9.0 1.7e-05 24.4 6.2 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) MutS_V PF00488.16 KUM61205.1 - 9.7e-77 257.5 0.0 1.4e-76 257.0 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KUM61205.1 - 7.6e-07 29.1 1.3 1.9e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 KUM61205.1 - 6.3e-06 26.2 0.0 1.3e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 KUM61205.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MutS_III PF05192.13 KUM61206.1 - 1.3e-25 90.3 0.2 1.8e-25 89.9 0.2 1.1 1 0 0 1 1 1 1 MutS domain III Ras PF00071.17 KUM61207.1 - 1.5e-63 213.0 0.2 1.7e-63 212.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KUM61207.1 - 1.2e-21 77.4 0.1 1.6e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KUM61207.1 - 2.4e-13 49.7 0.1 3.1e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KUM61207.1 - 2.9e-08 33.6 0.1 4.7e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KUM61207.1 - 5.9e-05 22.3 0.2 0.0001 21.5 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KUM61207.1 - 8.7e-05 22.0 0.1 0.0003 20.2 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KUM61207.1 - 9.1e-05 22.6 0.1 0.00024 21.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 KUM61207.1 - 0.00089 18.4 0.2 0.0012 17.9 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 KUM61207.1 - 0.0009 19.1 0.1 0.0024 17.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KUM61207.1 - 0.0026 16.9 0.1 0.0062 15.7 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 KUM61207.1 - 0.012 14.7 0.0 0.018 14.2 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 KUM61207.1 - 0.013 15.4 0.3 0.028 14.3 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 KUM61207.1 - 0.016 15.4 0.1 0.024 14.9 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 KUM61207.1 - 0.021 14.4 0.1 0.051 13.1 0.0 1.6 1 1 1 2 2 2 0 AAA domain FeoB_N PF02421.13 KUM61207.1 - 0.052 12.8 0.1 0.22 10.7 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B SpoIIID PF12116.3 KUM61207.1 - 0.064 13.1 0.1 0.85 9.5 0.0 2.1 2 0 0 2 2 2 0 Stage III sporulation protein D AAA_32 PF13654.1 KUM61207.1 - 0.1 11.2 0.1 0.82 8.2 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.1 KUM61207.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF4468 PF14730.1 KUM61207.1 - 0.11 12.1 0.1 0.36 10.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4468) with TBP-like fold AAA_5 PF07728.9 KUM61207.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.1 KUM61207.1 - 0.16 11.8 1.1 0.25 11.2 0.8 1.5 1 1 0 1 1 1 0 AAA domain Chromo PF00385.19 KUM61208.1 - 3.7e-06 26.4 2.4 7.3e-06 25.5 1.7 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1675 PF07897.6 KUM61208.1 - 0.21 11.4 6.6 0.49 10.2 4.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) HRXXH PF13933.1 KUM61209.1 - 3.2e-109 364.0 0.0 4e-109 363.7 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family PDZ_1 PF12812.2 KUM61209.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 PDZ-like domain Zip PF02535.17 KUM61210.1 - 1e-34 120.0 13.1 1e-34 120.0 9.1 2.0 2 0 0 2 2 2 1 ZIP Zinc transporter Acetyltransf_1 PF00583.19 KUM61211.1 - 1.7e-08 34.3 0.0 2.8e-08 33.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KUM61211.1 - 1.8e-07 31.2 0.0 2.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KUM61211.1 - 5.7e-07 29.4 0.1 0.00015 21.6 0.0 2.7 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KUM61211.1 - 4.2e-06 26.8 0.0 9.1e-05 22.5 0.0 2.3 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KUM61211.1 - 0.00095 18.8 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 KUM61211.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 KUM61211.1 - 0.026 14.4 0.0 0.11 12.3 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain WD40 PF00400.27 KUM61213.1 - 1.8e-31 106.8 13.0 2.3e-07 30.4 0.6 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Trypan_PARP PF05887.6 KUM61215.1 - 0.00094 19.0 86.8 0.13 12.0 16.0 4.7 1 1 1 3 3 3 3 Procyclic acidic repetitive protein (PARP) Amidohydro_5 PF13594.1 KUM61215.1 - 0.005 16.6 0.3 0.015 15.1 0.2 1.7 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.11 KUM61218.1 - 5.5e-32 110.8 41.1 5.5e-32 110.8 28.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM61218.1 - 9e-10 37.6 38.4 1.2e-08 34.0 9.2 2.9 2 1 0 3 3 3 2 Sugar (and other) transporter SHR3_chaperone PF08229.6 KUM61219.1 - 4.3e-79 264.0 0.0 5.6e-79 263.6 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 HlyIII PF03006.15 KUM61219.1 - 0.71 9.2 6.5 0.091 12.1 1.9 1.4 2 0 0 2 2 2 0 Haemolysin-III related Arrestin_N PF00339.24 KUM61220.1 - 2.1e-15 56.8 0.0 5.1e-14 52.3 0.0 2.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KUM61220.1 - 2.3e-07 30.9 0.8 0.00037 20.6 0.0 3.1 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Rrn6 PF10214.4 KUM61220.1 - 1.6 6.7 5.1 2.3 6.2 3.6 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SAM_2 PF07647.12 KUM61223.1 - 1.1e-11 44.4 0.1 2e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KUM61223.1 - 3.9e-09 36.5 0.2 1.1e-08 35.0 0.1 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH PF00169.24 KUM61223.1 - 1.3e-05 25.2 0.0 3.1e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 PH domain Fungal_trans_2 PF11951.3 KUM61224.1 - 1.2e-79 267.7 0.0 1.5e-79 267.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM61224.1 - 1e-07 31.6 8.5 1.8e-07 30.9 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APG5 PF04106.7 KUM61226.1 - 4.8e-64 215.4 0.0 6e-64 215.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Mnd1 PF03962.10 KUM61227.1 - 1.5e-47 161.6 3.4 1.7e-47 161.4 2.4 1.0 1 0 0 1 1 1 1 Mnd1 family DUF812 PF05667.6 KUM61227.1 - 0.0058 15.1 3.5 0.0067 15.0 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) UBA_e1_C PF09358.5 KUM61227.1 - 0.0062 16.7 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain DUF4423 PF14394.1 KUM61227.1 - 0.0074 15.8 0.3 0.037 13.5 0.0 2.1 2 1 1 3 3 3 1 Domain of unknown function (DUF4423) DUF904 PF06005.7 KUM61227.1 - 0.027 14.7 0.7 0.027 14.7 0.5 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF904) SGT1 PF07093.6 KUM61227.1 - 0.03 12.7 2.7 0.036 12.4 1.9 1.0 1 0 0 1 1 1 0 SGT1 protein Syntaxin-18_N PF10496.4 KUM61227.1 - 0.038 13.8 0.4 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus DUF4102 PF13356.1 KUM61227.1 - 0.042 13.7 0.5 0.11 12.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4102) TBPIP PF07106.8 KUM61227.1 - 0.12 11.9 3.2 3.3 7.2 1.2 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) OmpH PF03938.9 KUM61227.1 - 1.5 8.7 9.9 2.9 7.8 6.7 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) UAF_Rrn10 PF05234.6 KUM61228.1 - 0.00042 20.3 0.0 0.0007 19.6 0.0 1.4 1 0 0 1 1 1 1 UAF complex subunit Rrn10 Abhydrolase_6 PF12697.2 KUM61229.1 - 7.3e-22 78.3 0.1 5e-21 75.6 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM61229.1 - 8.1e-12 45.1 0.0 2.6e-11 43.5 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KUM61229.1 - 8.3e-10 38.5 0.0 2e-09 37.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KUM61229.1 - 5.4e-06 25.8 0.0 0.017 14.4 0.0 3.0 2 1 1 3 3 3 2 Dienelactone hydrolase family Hydrolase_4 PF12146.3 KUM61229.1 - 3.2e-05 23.6 0.0 8.4e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Putative lysophospholipase DUF2048 PF09752.4 KUM61229.1 - 0.002 17.0 0.4 0.0041 16.0 0.3 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Lipase_3 PF01764.20 KUM61229.1 - 0.014 15.0 0.4 0.066 12.8 0.2 2.0 2 0 0 2 2 2 0 Lipase (class 3) Sugar_tr PF00083.19 KUM61233.1 - 4.5e-130 434.2 25.2 5.1e-130 434.0 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM61233.1 - 5e-25 87.9 39.1 9.2e-20 70.6 10.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRP PF06011.7 KUM61234.1 - 7.3e-120 400.4 26.1 9.1e-120 400.1 18.1 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KUM61234.1 - 4.7e-33 114.2 0.1 7.4e-33 113.5 0.1 1.3 1 0 0 1 1 1 1 ML-like domain Methyltransf_11 PF08241.7 KUM61235.1 - 1.2e-06 28.8 0.0 2.2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM61235.1 - 6.7e-06 26.3 0.0 1.2e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM61235.1 - 1.8e-05 24.4 0.0 3.8e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KUM61235.1 - 0.00099 18.2 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KUM61235.1 - 0.0025 18.3 0.0 0.0087 16.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM61235.1 - 0.021 14.4 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 KUM61235.1 - 0.048 13.7 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Complex1_LYR_2 PF13233.1 KUM61236.1 - 6.8e-11 42.5 0.1 8.9e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KUM61236.1 - 2.6e-05 23.9 0.3 4.1e-05 23.3 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KUM61236.1 - 6.6e-05 23.0 0.3 9.7e-05 22.5 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like 4HBT_2 PF13279.1 KUM61237.1 - 2.3e-06 28.0 0.0 3.8e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Gluconate_2-dh3 PF13618.1 KUM61237.1 - 0.065 13.3 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 Mit_KHE1 PF10173.4 KUM61237.1 - 0.08 12.7 0.1 0.2 11.4 0.0 1.7 2 1 0 2 2 2 0 Mitochondrial K+-H+ exchange-related DUF4080 PF13311.1 KUM61237.1 - 0.085 12.8 0.2 0.13 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4080) PhoD PF09423.5 KUM61238.1 - 1.6e-05 23.6 0.0 0.00012 20.8 0.0 2.0 1 1 0 1 1 1 1 PhoD-like phosphatase Pyr_redox_2 PF07992.9 KUM61239.1 - 1.5e-27 96.7 0.1 1.9e-27 96.4 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KUM61239.1 - 7.7e-15 55.0 0.1 8.5e-13 48.5 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KUM61239.1 - 1.3e-09 38.4 0.1 5.1e-06 26.7 0.0 3.1 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM61239.1 - 7.1e-05 22.7 0.6 0.033 14.2 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 KUM61239.1 - 0.00016 21.8 0.1 0.019 15.2 0.0 3.1 2 2 1 3 3 3 1 Putative NAD(P)-binding Thi4 PF01946.12 KUM61239.1 - 0.00037 19.6 1.9 0.0028 16.8 0.1 2.5 2 1 0 2 2 2 1 Thi4 family K_oxygenase PF13434.1 KUM61239.1 - 0.0028 16.6 0.2 0.47 9.3 0.0 3.0 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 KUM61239.1 - 0.0095 16.0 0.1 0.91 9.6 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 KUM61239.1 - 0.013 14.3 3.4 4.4 6.0 0.0 3.5 2 2 2 4 4 4 0 FAD dependent oxidoreductase GIDA PF01134.17 KUM61239.1 - 0.023 13.5 3.1 5 5.8 0.0 3.7 4 1 1 5 5 5 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KUM61239.1 - 0.024 13.6 1.1 4.9 6.0 0.0 2.8 2 1 1 3 3 3 0 FAD binding domain FAD_oxidored PF12831.2 KUM61239.1 - 0.055 12.5 0.2 1.4 7.9 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KUM61239.1 - 0.18 10.6 4.7 0.6 8.8 0.1 3.5 3 1 0 4 4 4 0 FAD binding domain Dynamitin PF04912.9 KUM61240.1 - 1.7e-33 115.9 0.5 4e-16 58.7 0.0 2.2 2 0 0 2 2 2 2 Dynamitin CCDC32 PF14989.1 KUM61240.1 - 0.0048 16.7 1.6 0.071 12.9 0.5 2.5 2 0 0 2 2 2 1 Coiled-coil domain containing 32 DUF4200 PF13863.1 KUM61240.1 - 0.0068 16.3 6.4 0.045 13.7 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4200) NUDE_C PF04880.8 KUM61240.1 - 0.03 14.6 4.5 0.083 13.2 3.2 1.7 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DUF342 PF03961.8 KUM61240.1 - 0.034 12.5 0.1 0.28 9.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Laminin_II PF06009.7 KUM61240.1 - 0.046 13.4 4.4 0.08 12.6 0.0 3.2 3 1 1 4 4 4 0 Laminin Domain II Spc24 PF08286.6 KUM61240.1 - 0.049 13.3 2.5 2 8.0 0.1 2.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Prefoldin_2 PF01920.15 KUM61240.1 - 0.052 13.3 5.0 0.31 10.8 0.4 2.7 3 0 0 3 3 3 0 Prefoldin subunit TBPIP PF07106.8 KUM61240.1 - 0.067 12.7 0.1 7.1 6.1 0.0 2.5 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tropomyosin_1 PF12718.2 KUM61240.1 - 0.071 12.9 6.6 0.13 12.1 0.1 3.1 3 0 0 3 3 3 0 Tropomyosin like Spectrin PF00435.16 KUM61240.1 - 0.099 12.9 4.4 0.85 9.9 0.3 3.2 3 0 0 3 3 3 0 Spectrin repeat DivIC PF04977.10 KUM61240.1 - 0.21 11.1 6.8 0.92 9.0 0.1 3.5 3 1 0 3 3 3 0 Septum formation initiator Jnk-SapK_ap_N PF09744.4 KUM61240.1 - 0.21 11.5 2.8 3.9 7.4 0.0 2.4 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Prefoldin PF02996.12 KUM61240.1 - 0.28 10.8 4.9 0.32 10.6 0.2 3.0 3 1 0 3 3 3 0 Prefoldin subunit MbeD_MobD PF04899.7 KUM61240.1 - 0.3 11.0 4.1 1.5 8.7 0.3 3.3 4 0 0 4 4 3 0 MbeD/MobD like DUF972 PF06156.8 KUM61240.1 - 0.35 11.2 2.5 33 4.8 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF972) APG6 PF04111.7 KUM61240.1 - 0.81 8.6 2.7 4.7 6.1 0.1 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 Syntaxin-6_N PF09177.6 KUM61240.1 - 0.92 9.9 7.5 4.3 7.8 0.4 3.5 2 2 2 4 4 4 0 Syntaxin 6, N-terminal Tmemb_cc2 PF10267.4 KUM61240.1 - 7.8 4.9 10.8 23 3.4 4.9 2.5 2 1 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Glyco_transf_22 PF03901.12 KUM61241.1 - 1.6e-39 136.1 13.8 1.9e-39 135.8 9.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF1751 PF08551.5 KUM61241.1 - 1.1 9.6 6.3 36 4.7 0.1 3.6 3 0 0 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) Yos1 PF08571.5 KUM61242.1 - 1.9e-32 111.1 0.6 2.2e-32 111.0 0.4 1.0 1 0 0 1 1 1 1 Yos1-like UCH PF00443.24 KUM61243.1 - 1.1e-64 218.2 0.1 2.1e-64 217.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KUM61243.1 - 2.4e-32 112.5 2.3 1.9e-23 83.3 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 KUM61243.1 - 0.015 14.6 4.3 0.091 12.0 1.6 2.6 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase tRNA-synt_His PF13393.1 KUM61244.1 - 2.4e-38 131.9 0.0 2.4e-32 112.2 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 KUM61244.1 - 3.6e-18 65.7 0.0 2e-17 63.3 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KUM61244.1 - 8.1e-10 38.5 0.0 1.5e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 KUM61244.1 - 0.0004 19.2 0.0 0.0032 16.2 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) FAD_binding_3 PF01494.14 KUM61245.1 - 1.5e-21 76.8 0.0 3.6e-17 62.4 0.0 3.1 2 1 0 2 2 2 2 FAD binding domain SE PF08491.5 KUM61245.1 - 5.4e-06 25.4 0.0 8.5e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.7 KUM61245.1 - 0.0047 15.9 0.3 0.021 13.7 0.1 2.1 2 1 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 KUM61245.1 - 0.013 15.2 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding K_oxygenase PF13434.1 KUM61245.1 - 0.046 12.6 0.0 0.085 11.7 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KUM61245.1 - 0.055 13.3 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KUM61245.1 - 0.058 12.2 0.0 0.36 9.6 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 KUM61245.1 - 0.064 11.7 0.1 0.096 11.1 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 KUM61245.1 - 0.078 11.5 0.1 0.96 7.9 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase PX PF00787.19 KUM61246.1 - 3.2e-19 68.8 0.3 6.8e-19 67.7 0.2 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 KUM61246.1 - 9.3e-17 61.0 5.9 5.5e-08 32.3 0.3 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 KUM61246.1 - 0.019 14.4 4.2 0.28 10.6 2.9 2.3 1 1 0 1 1 1 0 BAR domain DUF724 PF05266.9 KUM61246.1 - 0.1 12.2 2.0 9.2 5.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF1664 PF07889.7 KUM61246.1 - 0.39 10.5 1.4 7.2 6.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.15 KUM61246.1 - 0.65 9.7 4.4 1.5 8.6 0.1 2.4 2 0 0 2 2 2 0 Prefoldin subunit TMF_DNA_bd PF12329.3 KUM61246.1 - 0.71 9.7 3.4 5 7.0 0.2 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.3 KUM61246.1 - 1.9 8.3 5.9 13 5.6 0.0 2.5 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 KUM61246.1 - 3.8 7.0 6.2 3.9 7.0 0.2 2.2 2 0 0 2 2 2 0 IncA protein Peptidase_S8 PF00082.17 KUM61247.1 - 4.3e-51 173.7 0.5 6.5e-51 173.1 0.3 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 KUM61247.1 - 2.1e-27 94.7 0.1 3.9e-27 93.8 0.1 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Amino_oxidase PF01593.19 KUM61248.1 - 7.8e-91 305.3 0.0 1.1e-90 304.9 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 KUM61248.1 - 3.8e-11 42.9 0.0 8.7e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.1 KUM61248.1 - 7.2e-07 29.1 0.0 1.6e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.14 KUM61248.1 - 0.00019 21.6 0.7 0.00041 20.5 0.5 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box DAO PF01266.19 KUM61248.1 - 0.0022 16.9 0.1 0.025 13.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KUM61248.1 - 0.019 15.0 0.0 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KUM61248.1 - 0.065 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KUM61248.1 - 0.11 10.9 0.0 1.1 7.6 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein HpcH_HpaI PF03328.9 KUM61249.1 - 7.3e-39 132.9 0.0 2.2e-38 131.3 0.0 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 KUM61249.1 - 2.1e-12 46.5 0.0 1.1e-06 27.6 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF1771 PF08590.5 KUM61250.1 - 2.5e-16 59.4 9.7 2.5e-16 59.4 6.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 KUM61250.1 - 2.3e-13 50.1 0.1 1.2e-12 47.8 0.1 2.3 2 0 0 2 2 2 1 Smr domain zf-CCCH PF00642.19 KUM61250.1 - 1.3e-06 27.9 2.2 0.0046 16.6 0.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CUE PF02845.11 KUM61250.1 - 0.14 11.6 1.6 0.21 11.0 0.1 2.1 2 0 0 2 2 2 0 CUE domain Aldedh PF00171.17 KUM61252.1 - 9.3e-135 449.5 0.5 1.1e-134 449.2 0.4 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family POM121 PF15229.1 KUM61252.1 - 0.034 13.5 2.8 0.068 12.5 2.0 1.5 1 0 0 1 1 1 0 POM121 family Pkinase_C PF00433.19 KUM61252.1 - 0.14 12.7 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein kinase C terminal domain Calreticulin PF00262.13 KUM61253.1 - 6.8e-164 544.8 15.8 9.3e-164 544.3 11.0 1.2 1 0 0 1 1 1 1 Calreticulin family DUF3227 PF11537.3 KUM61253.1 - 0.035 14.1 0.0 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3227) p450 PF00067.17 KUM61254.1 - 2.1e-71 240.8 0.0 2.7e-71 240.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Vps5 PF09325.5 KUM61255.1 - 6e-88 294.0 4.6 8.8e-88 293.5 3.2 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KUM61255.1 - 2.6e-23 81.9 0.0 5.6e-23 80.8 0.0 1.6 1 0 0 1 1 1 1 PX domain zf-C4H2 PF10146.4 KUM61255.1 - 2.2 8.2 5.1 0.2 11.6 0.1 1.8 2 0 0 2 2 2 0 Zinc finger-containing protein Aldolase_II PF00596.16 KUM61256.1 - 3.7e-39 134.2 0.0 4.4e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Flavin_Reduct PF01613.13 KUM61258.1 - 3.1e-28 98.5 0.4 5.9e-28 97.6 0.3 1.5 1 1 0 1 1 1 1 Flavin reductase like domain DUF4505 PF14956.1 KUM61258.1 - 0.036 13.7 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4505) AlaDh_PNT_N PF05222.10 KUM61258.1 - 0.12 12.4 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, N-terminal domain NUDIX PF00293.23 KUM61260.1 - 9.1e-17 60.9 0.0 1.4e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain INCENP_ARK-bind PF03941.10 KUM61262.1 - 5e-18 64.6 1.3 5e-18 64.6 0.9 2.1 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region PTR2 PF00854.16 KUM61263.1 - 8.3e-29 100.5 3.6 7.6e-14 51.2 0.1 2.1 1 1 1 2 2 2 2 POT family HlyIII PF03006.15 KUM61263.1 - 0.038 13.4 7.6 0.31 10.4 0.3 2.4 2 0 0 2 2 2 0 Haemolysin-III related MFS_1 PF07690.11 KUM61264.1 - 1.7e-26 92.7 35.9 1.2e-25 89.9 24.1 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM61264.1 - 0.0048 15.1 2.9 0.0067 14.6 2.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Git3_C PF11970.3 KUM61265.1 - 0.0034 17.1 0.1 0.8 9.5 0.0 2.1 2 0 0 2 2 2 2 G protein-coupled glucose receptor regulating Gpa2 C-term Zn_clus PF00172.13 KUM61267.1 - 2.1e-08 33.9 12.1 3.2e-08 33.3 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KUM61267.1 - 0.0039 15.8 0.0 0.0091 14.6 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF4385 PF14328.1 KUM61267.1 - 0.13 12.1 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4385) PIF1 PF05970.9 KUM61269.1 - 3.2e-11 42.7 0.0 4.1e-11 42.4 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KUM61269.1 - 2e-10 40.5 0.0 2.5e-10 40.2 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KUM61269.1 - 7.3e-05 22.4 0.1 9.9e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain Torsin PF06309.6 KUM61269.1 - 0.01 15.7 0.0 0.016 15.0 0.0 1.4 1 1 0 1 1 1 0 Torsin AAA_5 PF07728.9 KUM61269.1 - 0.018 14.7 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KUM61269.1 - 0.022 14.7 0.0 0.33 10.9 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.10 KUM61269.1 - 0.042 13.5 0.2 7.5 6.2 0.1 2.1 2 0 0 2 2 2 0 NTPase Sigma54_activat PF00158.21 KUM61269.1 - 0.045 13.2 0.0 0.17 11.3 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.1 KUM61269.1 - 0.081 12.4 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 KUM61269.1 - 0.088 13.0 0.2 0.19 11.9 0.1 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RHS_repeat PF05593.9 KUM61270.1 - 1e-15 57.3 61.3 1.9e-05 24.6 0.0 17.0 13 5 5 19 19 19 11 RHS Repeat Reticulon PF02453.12 KUM61272.1 - 2.2e-36 125.0 2.6 3e-36 124.5 1.8 1.2 1 0 0 1 1 1 1 Reticulon BRX_N PF13713.1 KUM61272.1 - 0.034 13.6 0.0 0.078 12.4 0.0 1.5 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain RabGAP-TBC PF00566.13 KUM61273.1 - 2.6e-48 164.3 0.0 8e-48 162.7 0.0 1.9 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF972 PF06156.8 KUM61273.1 - 0.52 10.6 0.0 0.52 10.6 0.0 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF972) DNA_topoisoIV PF00521.15 KUM61274.1 - 6.5e-134 446.9 0.0 1.1e-133 446.1 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 KUM61274.1 - 1e-32 112.7 0.3 3.1e-32 111.1 0.2 1.8 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 KUM61274.1 - 3e-13 49.6 0.0 1.6e-12 47.2 0.0 2.3 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 KUM61274.1 - 1.6e-10 40.6 0.0 5.2e-10 39.0 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PspA_IM30 PF04012.7 KUM61277.1 - 0.0004 19.8 3.2 0.00041 19.7 2.2 1.0 1 0 0 1 1 1 1 PspA/IM30 family HTH_10 PF04967.7 KUM61277.1 - 0.1 12.2 0.0 0.23 11.0 0.0 1.6 2 0 0 2 2 2 0 HTH DNA binding domain Tox-URI2 PF15653.1 KUM61277.1 - 0.12 12.6 2.4 0.14 12.3 1.7 1.1 1 0 0 1 1 1 0 URI fold toxin 2 DUF3073 PF11273.3 KUM61277.1 - 0.96 10.0 5.6 1.9 9.0 3.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3073) DUF3405 PF11885.3 KUM61278.1 - 5.9e-117 390.9 3.5 6.6e-117 390.7 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Glyco_hydro_92 PF07971.7 KUM61279.1 - 7.6e-174 579.0 0.3 9.6e-174 578.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 adh_short PF00106.20 KUM61280.1 - 1.8e-28 99.5 6.6 2.4e-28 99.1 4.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM61280.1 - 1.7e-25 90.1 3.6 2e-25 89.9 2.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM61280.1 - 7.4e-12 45.2 4.4 1.2e-11 44.6 3.0 1.2 1 0 0 1 1 1 1 KR domain ACT PF01842.20 KUM61280.1 - 0.035 13.6 0.1 0.078 12.4 0.1 1.6 1 0 0 1 1 1 0 ACT domain Epimerase PF01370.16 KUM61280.1 - 0.041 13.3 0.3 0.053 12.9 0.2 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.22 KUM61280.1 - 0.085 13.2 0.8 0.16 12.3 0.6 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HSP33 PF01430.14 KUM61280.1 - 0.14 11.2 0.3 0.18 10.8 0.2 1.2 1 0 0 1 1 1 0 Hsp33 protein FAD_binding_3 PF01494.14 KUM61281.1 - 2.4e-73 247.2 0.0 3.1e-73 246.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KUM61281.1 - 2.8e-33 114.8 0.0 5e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 KUM61281.1 - 0.0001 21.3 0.1 0.0022 16.9 0.0 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KUM61281.1 - 0.00015 21.7 0.0 0.00032 20.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KUM61281.1 - 0.00022 21.5 0.0 0.002 18.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KUM61281.1 - 0.00034 20.7 0.1 0.0014 18.7 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KUM61281.1 - 0.00042 18.9 0.1 0.00064 18.3 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 KUM61281.1 - 0.0017 18.3 0.0 0.0059 16.4 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KUM61281.1 - 0.0064 15.6 0.1 0.014 14.4 0.1 1.5 1 0 0 1 1 1 1 Thi4 family 2-Hacid_dh_C PF02826.14 KUM61281.1 - 0.0075 15.4 0.0 1.3 8.1 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KUM61281.1 - 0.0086 15.0 0.1 0.013 14.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein 3HCDH_N PF02737.13 KUM61281.1 - 0.044 13.4 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 KUM61281.1 - 0.05 12.2 0.0 0.072 11.7 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_2 PF00890.19 KUM61281.1 - 0.074 11.8 0.1 0.14 10.9 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain CMAS PF02353.15 KUM61282.1 - 2.9e-58 197.1 0.3 3.6e-58 196.8 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KUM61282.1 - 8.5e-11 41.8 0.0 1.9e-10 40.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM61282.1 - 3.5e-06 27.4 0.0 6.1e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KUM61282.1 - 0.00013 21.9 0.0 0.001 19.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KUM61282.1 - 0.00031 20.1 0.0 0.00054 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KUM61282.1 - 0.00084 19.9 0.0 0.0022 18.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM61282.1 - 0.0023 18.3 0.0 0.0042 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM61282.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.8 KUM61282.1 - 0.014 14.7 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 PCMT PF01135.14 KUM61282.1 - 0.015 14.8 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 KUM61282.1 - 0.043 14.1 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Lactamase_B PF00753.22 KUM61283.1 - 4.3e-07 29.7 0.0 9.4e-07 28.6 0.0 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KUM61283.1 - 0.00054 19.5 0.2 0.00093 18.7 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain FAD_binding_3 PF01494.14 KUM61284.1 - 8e-13 48.1 0.0 3.4e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KUM61284.1 - 2.5e-07 29.9 6.2 0.002 17.1 2.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 KUM61284.1 - 9.5e-07 27.6 0.3 2.6e-06 26.1 0.2 1.6 1 1 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 KUM61284.1 - 1.9e-06 26.7 3.4 0.0087 14.7 0.1 2.1 1 1 1 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.22 KUM61284.1 - 3e-05 24.3 1.7 0.038 14.4 0.9 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KUM61284.1 - 3.7e-05 22.7 5.4 0.0003 19.7 3.4 2.3 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 KUM61284.1 - 7.5e-05 22.6 0.5 0.00029 20.7 0.3 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 KUM61284.1 - 0.00068 19.3 0.3 0.0012 18.5 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KUM61284.1 - 0.00069 19.2 0.3 0.0013 18.3 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.9 KUM61284.1 - 0.0018 18.2 0.4 0.0041 17.0 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KUM61284.1 - 0.0021 17.0 0.8 0.01 14.7 0.6 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein Rossmann-like PF10727.4 KUM61284.1 - 0.033 13.9 0.1 0.08 12.6 0.1 1.6 1 0 0 1 1 1 0 Rossmann-like domain GIDA PF01134.17 KUM61284.1 - 0.051 12.4 3.2 0.085 11.7 2.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.12 KUM61284.1 - 0.076 12.0 0.3 0.17 10.9 0.2 1.6 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.2 KUM61284.1 - 0.11 11.5 2.9 0.37 9.8 1.8 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase SE PF08491.5 KUM61284.1 - 0.19 10.5 0.0 0.39 9.4 0.0 1.5 2 0 0 2 2 2 0 Squalene epoxidase Glycoprotein_B PF00606.13 KUM61286.1 - 0.84 7.5 5.9 0.57 8.1 3.3 1.3 1 1 0 1 1 1 0 Herpesvirus Glycoprotein B MFS_1 PF07690.11 KUM61287.1 - 3.6e-25 88.4 47.3 7.7e-24 84.0 18.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM61287.1 - 5e-18 64.9 18.9 5.4e-18 64.7 12.5 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter Bul1_N PF04425.7 KUM61288.1 - 0.0014 17.2 0.7 0.0021 16.6 0.5 1.3 1 0 0 1 1 1 1 Bul1 N terminus Bul1_C PF04426.7 KUM61288.1 - 0.0029 16.8 0.0 0.0046 16.2 0.0 1.3 1 0 0 1 1 1 1 Bul1 C terminus CtaG_Cox11 PF04442.9 KUM61288.1 - 0.11 12.2 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein CtaG/Cox11 UPF0233 PF06781.7 KUM61289.1 - 0.013 15.1 0.2 0.016 14.8 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) DUF2370 PF10176.4 KUM61289.1 - 0.048 12.9 0.3 0.055 12.8 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Mid2 PF04478.7 KUM61289.1 - 0.091 12.1 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF2207 PF09972.4 KUM61289.1 - 0.096 11.2 0.0 0.1 11.1 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) NicO PF03824.11 KUM61289.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein DUF2839 PF10999.3 KUM61289.1 - 0.12 12.4 0.3 0.16 12.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) Synaptobrevin PF00957.16 KUM61289.1 - 0.14 11.7 0.2 0.19 11.3 0.2 1.2 1 0 0 1 1 1 0 Synaptobrevin PDR_CDR PF06422.7 KUM61289.1 - 1 9.0 2.9 1.4 8.6 1.8 1.3 1 1 0 1 1 1 0 CDR ABC transporter Amidase PF01425.16 KUM61290.1 - 3.5e-81 273.3 0.0 4.6e-81 272.9 0.0 1.2 1 0 0 1 1 1 1 Amidase Pkinase PF00069.20 KUM61292.1 - 8.4e-16 57.8 0.0 1.1e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM61292.1 - 0.0024 16.9 0.1 0.0047 16.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Ring_hydroxyl_A PF00848.14 KUM61295.1 - 1.7e-31 109.5 3.8 8.1e-31 107.3 2.6 2.0 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 KUM61295.1 - 4.5e-14 51.7 0.0 9.3e-14 50.7 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain adh_short_C2 PF13561.1 KUM61297.1 - 3.4e-32 112.1 0.0 4e-32 111.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KUM61297.1 - 6.9e-19 68.3 0.2 8.6e-19 68.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM61297.1 - 2e-10 40.6 0.0 3e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 KR domain COesterase PF00135.23 KUM61298.1 - 9.3e-97 324.9 0.0 1.4e-96 324.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KUM61298.1 - 3e-10 40.0 0.5 1.1e-09 38.2 0.3 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KUM61298.1 - 9.9e-05 21.6 0.2 0.00017 20.8 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Tme5_EGF_like PF09064.5 KUM61298.1 - 0.074 12.6 0.0 0.22 11.1 0.0 1.8 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like DLH PF01738.13 KUM61300.1 - 2.1e-12 46.8 0.0 2.4e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KUM61300.1 - 0.029 14.1 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.11 KUM61301.1 - 1e-38 132.9 44.4 1e-38 132.9 30.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM61301.1 - 4.4e-10 38.7 30.1 1.6e-09 36.8 20.8 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Fungal_trans PF04082.13 KUM61303.1 - 2.2e-16 59.5 1.0 3.1e-16 59.0 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain PSDC PF12588.3 KUM61304.1 - 4.8e-54 181.8 0.0 6.8e-54 181.3 0.0 1.2 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 KUM61304.1 - 3.5e-35 121.1 0.0 5.4e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.1 KUM61304.1 - 0.034 13.8 0.1 12 5.6 0.0 2.5 2 0 0 2 2 2 0 Biotin-lipoyl like MFS_1 PF07690.11 KUM61305.1 - 8.6e-31 106.9 29.4 8.6e-31 106.9 20.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L7Ae PF01248.21 KUM61306.1 - 4.3e-26 90.2 0.0 5.2e-26 89.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KUM61306.1 - 0.00011 22.1 0.0 0.00011 22.0 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 DUF1962 PF09227.5 KUM61307.1 - 1.8e-30 104.7 14.5 2.2e-30 104.5 10.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1962) Mg-por_mtran_C PF07109.6 KUM61308.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Magnesium-protoporphyrin IX methyltransferase C-terminus Glyco_transf_8 PF01501.15 KUM61309.1 - 9.5e-28 97.1 0.0 1.3e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 XPG_N PF00752.12 KUM61310.1 - 2.3e-05 24.5 0.0 5e-05 23.5 0.0 1.5 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 KUM61311.1 - 1.5e-29 101.8 0.0 4.3e-29 100.4 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KUM61311.1 - 4.7e-16 58.8 0.2 2.5e-15 56.5 0.0 2.2 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 KUM61311.1 - 0.0001 22.4 0.3 0.00082 19.5 0.0 2.4 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold PcfK PF14058.1 KUM61311.1 - 0.23 11.6 11.1 1.1 9.4 3.4 3.0 3 0 0 3 3 3 0 PcfK-like protein HXXSHH PF07586.6 KUM61311.1 - 0.84 8.4 4.1 1.4 7.7 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Acyl-CoA_dh_N PF02771.11 KUM61312.1 - 8.3e-27 94.0 0.2 1.9e-26 92.8 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 KUM61312.1 - 6.8e-25 87.9 1.5 1.3e-24 86.9 1.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KUM61312.1 - 1.1e-16 60.0 0.0 2.3e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KUM61312.1 - 5.9e-09 36.2 1.7 5.9e-09 36.2 1.2 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Zn_clus PF00172.13 KUM61313.1 - 1.6e-08 34.3 8.4 2.5e-08 33.6 5.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KUM61313.1 - 1e-05 24.5 0.5 2.3e-05 23.3 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyoxalase_2 PF12681.2 KUM61314.1 - 6e-09 36.4 0.0 1.3e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KUM61314.1 - 0.0022 17.9 0.0 0.0058 16.5 0.0 1.7 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Rick_17kDa_Anti PF05433.10 KUM61314.1 - 0.014 15.0 3.1 0.03 13.9 2.2 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF3552 PF12072.3 KUM61314.1 - 0.02 14.1 3.2 0.075 12.2 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Gly-zipper_Omp PF13488.1 KUM61314.1 - 0.038 13.6 4.2 0.08 12.5 2.9 1.4 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_OmpA PF13436.1 KUM61314.1 - 0.67 9.6 5.9 0.14 11.7 0.6 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain UQ_con PF00179.21 KUM61315.1 - 5.9e-51 171.5 0.0 6.9e-51 171.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KUM61315.1 - 0.00011 21.9 0.0 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KUM61315.1 - 0.0057 16.5 0.0 0.0065 16.3 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KUM61315.1 - 0.033 13.8 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 UEV domain Acetyltransf_13 PF13880.1 KUM61316.1 - 2.7e-29 100.7 0.0 6.2e-29 99.5 0.0 1.7 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 KUM61316.1 - 8.4e-17 60.4 0.2 1.6e-16 59.6 0.2 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO EMG1 PF03587.9 KUM61317.1 - 1.1e-79 266.3 0.1 1.6e-79 265.8 0.1 1.2 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase M_domain PF12938.2 KUM61318.1 - 2.1 8.0 13.4 1.3 8.7 1.8 2.4 2 1 0 2 2 2 0 M domain of GW182 HUN PF08729.5 KUM61320.1 - 2.1e-14 53.0 0.1 4.4e-14 52.0 0.1 1.5 1 0 0 1 1 1 1 HPC2 and ubinuclein domain RPAP1_C PF08620.5 KUM61321.1 - 1.3e-29 101.8 0.0 3.6e-29 100.4 0.0 1.8 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 KUM61321.1 - 4.5e-18 64.5 9.1 2.1e-17 62.4 6.4 2.0 2 0 0 2 2 2 1 RPAP1-like, N-terminal Pkinase PF00069.20 KUM61322.1 - 2.3e-60 203.9 0.0 3.1e-60 203.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM61322.1 - 1.3e-35 122.6 0.0 1.8e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM61322.1 - 1.3e-05 24.3 0.0 2.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KUM61322.1 - 0.027 13.3 0.0 0.039 12.7 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 KUM61322.1 - 0.081 12.6 0.0 0.38 10.4 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 KUM61322.1 - 0.099 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family eIF2A PF08662.6 KUM61323.1 - 1.1e-81 273.2 0.0 7e-81 270.5 0.0 2.2 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 KUM61323.1 - 3.7e-06 26.6 0.1 0.067 13.1 0.1 4.8 4 0 0 4 4 4 1 WD domain, G-beta repeat CDV3 PF15359.1 KUM61323.1 - 0.01 15.9 0.5 0.01 15.9 0.4 4.0 3 1 0 3 3 3 0 Carnitine deficiency-associated protein 3 Apc1 PF12859.2 KUM61325.1 - 5.8e-32 110.0 0.1 1.9e-31 108.3 0.1 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 KUM61325.1 - 3.1e-08 33.4 3.7 0.12 12.6 0.1 4.3 4 0 0 4 4 4 3 Proteasome/cyclosome repeat DUF1979 PF09322.5 KUM61326.1 - 0.024 14.2 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1979) TFIID_20kDa PF03847.8 KUM61327.1 - 5.9e-21 74.5 0.0 1e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 KUM61327.1 - 0.033 14.3 0.0 0.071 13.2 0.0 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KUM61327.1 - 0.063 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PIP5K PF01504.13 KUM61328.1 - 1.9e-87 292.5 0.0 3.1e-87 291.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Linker_histone PF00538.14 KUM61331.1 - 1.4e-22 79.5 0.4 2.6e-22 78.6 0.3 1.4 1 0 0 1 1 1 1 linker histone H1 and H5 family PRANC PF09372.5 KUM61331.1 - 0.33 10.9 1.8 3.4 7.7 0.9 2.0 1 1 1 2 2 2 0 PRANC domain Pneumo_phosprot PF02478.11 KUM61331.1 - 1.1 8.7 0.0 1.1 8.7 0.0 2.6 1 1 1 2 2 2 0 Pneumovirus phosphoprotein Oxysterol_BP PF01237.13 KUM61333.1 - 4e-118 393.9 0.0 1e-117 392.5 0.0 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 KUM61333.1 - 5.6e-38 128.8 0.1 1.1e-37 127.9 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KUM61333.1 - 7.6e-05 22.8 0.1 0.00031 20.8 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 KUM61333.1 - 0.00019 21.6 1.2 0.0025 18.0 0.9 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain GOLD_2 PF13897.1 KUM61333.1 - 0.0074 16.5 1.4 0.012 15.8 0.0 2.1 3 0 0 3 3 3 1 Golgi-dynamics membrane-trafficking SH2_2 PF14633.1 KUM61334.1 - 1.8e-83 278.9 0.0 5.8e-83 277.3 0.0 1.9 2 0 0 2 2 2 1 SH2 domain DLD PF14878.1 KUM61334.1 - 9.8e-39 132.0 4.9 9.8e-38 128.7 3.4 2.9 1 0 0 1 1 1 1 Death-like domain of SPT6 HHH_7 PF14635.1 KUM61334.1 - 1.1e-31 108.9 0.0 2.3e-31 107.9 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 KUM61334.1 - 8.2e-28 96.8 0.0 2.2e-27 95.4 0.0 1.8 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.1 KUM61334.1 - 5.2e-20 71.6 3.0 5.7e-19 68.2 2.1 2.6 1 1 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.1 KUM61334.1 - 4.2e-19 68.5 19.0 4.2e-19 68.5 13.2 5.1 5 1 1 6 6 6 1 Acidic N-terminal SPT6 SH2 PF00017.19 KUM61334.1 - 0.0002 21.1 0.0 0.00049 19.8 0.0 1.7 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.2 KUM61334.1 - 0.0052 16.6 0.0 0.016 15.1 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif B12-binding PF02310.14 KUM61334.1 - 0.031 14.1 0.0 0.093 12.6 0.0 1.8 1 0 0 1 1 1 0 B12 binding domain NAD_binding_1 PF00175.16 KUM61335.1 - 6.2e-12 46.0 0.0 1.1e-11 45.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KUM61335.1 - 5.3e-09 36.0 0.0 9.1e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.17 KUM61335.1 - 8.1e-09 35.8 0.0 2.4e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Globin NAD_binding_6 PF08030.7 KUM61335.1 - 1.9e-05 24.5 0.0 0.00017 21.5 0.0 2.4 2 1 1 3 3 3 1 Ferric reductase NAD binding domain Guanylate_kin PF00625.16 KUM61335.1 - 0.00035 20.0 0.1 0.00082 18.8 0.0 1.6 1 1 0 1 1 1 1 Guanylate kinase Protoglobin PF11563.3 KUM61335.1 - 0.011 15.3 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 Protoglobin MIP PF00230.15 KUM61336.1 - 7.9e-46 156.3 7.9 1e-45 155.9 5.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF3533 PF12051.3 KUM61338.1 - 1.6e-126 422.1 9.1 1.8e-126 421.9 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF202 PF02656.10 KUM61338.1 - 0.085 13.0 0.0 0.085 13.0 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF202) Sugar_tr PF00083.19 KUM61339.1 - 8.8e-34 116.8 22.7 1.7e-32 112.6 15.7 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM61339.1 - 1.3e-25 89.9 25.0 1.3e-25 89.9 17.3 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KUM61339.1 - 3e-05 22.6 19.4 0.00015 20.3 4.3 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein Acetyltransf_1 PF00583.19 KUM61340.1 - 0.0045 17.0 0.0 0.0094 15.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family OPT PF03169.10 KUM61340.1 - 0.032 12.6 0.6 0.056 11.8 0.0 1.6 2 0 0 2 2 2 0 OPT oligopeptide transporter protein Acetyltransf_7 PF13508.1 KUM61340.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Complex1_LYR PF05347.10 KUM61341.1 - 1.7e-05 24.4 0.3 2.9e-05 23.7 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KUM61341.1 - 0.00016 21.8 0.1 0.00028 21.0 0.1 1.4 1 0 0 1 1 1 1 Complex1_LYR-like DnaJ PF00226.26 KUM61342.1 - 4.8e-18 64.6 0.5 4.8e-18 64.6 0.3 2.4 2 0 0 2 2 2 1 DnaJ domain ECH PF00378.15 KUM61343.1 - 3.1e-33 114.9 0.0 3.9e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family PQ-loop PF04193.9 KUM61344.1 - 0.00015 21.2 1.4 0.00043 19.7 0.1 2.4 1 1 0 2 2 2 1 PQ loop repeat BCLP PF12304.3 KUM61344.1 - 0.44 9.9 4.9 1.8 7.9 3.4 1.9 1 1 0 1 1 1 0 Beta-casein like protein Sterol_MT_C PF08498.5 KUM61345.1 - 1.7e-27 95.1 0.0 3e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 KUM61345.1 - 5.3e-22 78.1 0.0 1.1e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM61345.1 - 9.1e-17 61.0 0.0 1.3e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM61345.1 - 1e-13 51.5 0.0 1.8e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM61345.1 - 3.3e-13 49.6 0.1 5.7e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM61345.1 - 1.9e-11 44.5 0.0 4.4e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KUM61345.1 - 1.1e-10 41.0 0.1 1.7e-10 40.4 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 KUM61345.1 - 6.4e-10 38.5 0.0 1e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KUM61345.1 - 2.6e-09 37.4 0.0 5.2e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KUM61345.1 - 7.5e-09 35.6 0.0 2.5e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 KUM61345.1 - 3.6e-05 23.3 0.0 5.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 KUM61345.1 - 0.00043 19.7 0.0 0.00079 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.15 KUM61345.1 - 0.00085 18.4 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PrmA PF06325.8 KUM61345.1 - 0.0011 18.1 0.0 0.0018 17.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 KUM61345.1 - 0.0011 18.5 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_29 PF03141.11 KUM61345.1 - 0.0013 17.1 0.0 0.0017 16.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.7 KUM61345.1 - 0.0074 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 KUM61345.1 - 0.052 13.2 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 KUM61345.1 - 0.069 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 RRM_5 PF13893.1 KUM61346.1 - 1.6e-10 40.6 0.0 2.8e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KUM61346.1 - 1.9e-08 33.8 0.0 3.2e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM61346.1 - 0.00022 21.1 0.0 0.00036 20.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KUM61346.1 - 0.0019 17.9 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Pectate_lyase_3 PF12708.2 KUM61347.1 - 1.2e-50 172.7 16.4 2.2e-37 129.3 4.2 3.3 3 1 0 3 3 3 2 Pectate lyase superfamily protein Beta_helix PF13229.1 KUM61347.1 - 0.0058 16.4 6.2 0.0058 16.4 4.3 2.2 2 0 0 2 2 2 1 Right handed beta helix region End_N_terminal PF12218.3 KUM61347.1 - 0.044 13.2 1.4 0.069 12.6 0.0 2.1 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase CCDC14 PF15254.1 KUM61347.1 - 8.7 4.5 6.7 12 4.0 4.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 AA_permease_2 PF13520.1 KUM61349.1 - 5e-66 222.9 43.1 6.1e-66 222.7 29.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM61349.1 - 1.3e-13 50.1 36.8 1.8e-13 49.6 25.5 1.2 1 0 0 1 1 1 1 Amino acid permease SLAIN PF15301.1 KUM61349.1 - 0.082 12.0 0.4 0.12 11.4 0.3 1.1 1 0 0 1 1 1 0 SLAIN motif-containing family Herpes_US9 PF06072.6 KUM61349.1 - 0.93 9.3 0.0 0.93 9.3 0.0 4.7 5 0 0 5 5 5 0 Alphaherpesvirus tegument protein US9 Arc PF03869.9 KUM61350.1 - 0.0069 15.9 0.1 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 Arc-like DNA binding domain DUF883 PF05957.8 KUM61350.1 - 0.6 10.5 4.7 14 6.1 1.5 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Alpha_GJ PF03229.8 KUM61351.1 - 0.0079 16.5 17.4 0.22 11.8 5.6 2.2 2 0 0 2 2 2 2 Alphavirus glycoprotein J LIF_OSM PF01291.12 KUM61351.1 - 0.04 13.8 0.5 0.054 13.4 0.4 1.2 1 0 0 1 1 1 0 LIF / OSM family DUF3533 PF12051.3 KUM61351.1 - 0.047 12.4 0.6 0.056 12.1 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Sugar_tr PF00083.19 KUM61352.1 - 1.1e-104 350.5 22.3 1.5e-104 350.0 15.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM61352.1 - 1.6e-28 99.4 35.6 2.7e-19 69.1 8.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 KUM61352.1 - 0.011 14.4 7.0 0.53 8.9 0.3 2.6 2 1 1 3 3 3 0 BT1 family DUF3169 PF11368.3 KUM61352.1 - 0.87 8.7 4.3 0.47 9.6 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) HLH PF00010.21 KUM61353.1 - 2.2e-10 40.0 0.0 4.3e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF605 PF04652.11 KUM61353.1 - 0.55 9.5 18.7 0.67 9.2 12.9 1.1 1 0 0 1 1 1 0 Vta1 like AA_permease_2 PF13520.1 KUM61354.1 - 2.1e-56 191.2 49.2 2.7e-56 190.9 34.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM61354.1 - 1.6e-24 86.0 39.4 2.1e-24 85.7 27.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4235 PF14019.1 KUM61354.1 - 0.036 13.9 0.2 0.098 12.5 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) DUF3493 PF11998.3 KUM61354.1 - 0.14 12.0 2.6 0.18 11.7 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3493) DUF1182 PF06681.8 KUM61354.1 - 2.1 7.4 11.8 0.062 12.5 1.3 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1182) Pro-kuma_activ PF09286.6 KUM61355.1 - 8e-35 119.9 0.1 2e-34 118.6 0.1 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KUM61355.1 - 4.6e-14 52.2 0.3 9e-14 51.2 0.0 1.5 2 0 0 2 2 2 1 Subtilase family adh_short PF00106.20 KUM61356.1 - 4e-08 33.3 0.5 8.7e-08 32.2 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM61356.1 - 0.00018 21.3 0.0 0.00026 20.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM61356.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 KR domain NmrA PF05368.8 KUM61357.1 - 7.1e-22 77.7 0.0 8.8e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KUM61357.1 - 1.2e-12 48.2 0.0 1.7e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KUM61357.1 - 0.00028 19.6 0.0 0.00046 18.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family APH PF01636.18 KUM61360.1 - 8.7e-07 28.9 0.0 1.2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KUM61360.1 - 0.0073 15.4 0.0 0.009 15.1 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 KUM61360.1 - 0.031 12.9 0.0 0.039 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Ank_2 PF12796.2 KUM61361.1 - 3e-70 232.6 0.3 3.6e-16 59.2 0.0 6.7 3 2 5 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.25 KUM61361.1 - 1.1e-47 157.5 14.2 7.2e-09 35.0 0.0 11.9 13 0 0 13 13 13 9 Ankyrin repeat Ank_3 PF13606.1 KUM61361.1 - 9.1e-41 133.8 3.6 8.8e-07 28.5 0.0 12.3 13 0 0 13 13 13 9 Ankyrin repeat Ank_4 PF13637.1 KUM61361.1 - 3.4e-34 116.5 8.9 0.00019 21.8 0.2 9.7 6 2 3 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM61361.1 - 5.6e-31 105.8 13.5 3.5e-07 30.2 0.0 10.9 8 3 4 12 12 12 6 Ankyrin repeats (many copies) Phosphoesterase PF04185.9 KUM61362.1 - 4.9e-32 111.5 0.7 1.6e-31 109.8 0.5 1.7 1 1 0 1 1 1 1 Phosphoesterase family DUF1464 PF07318.7 KUM61363.1 - 0.091 11.5 0.0 0.097 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) Methyltransf_2 PF00891.13 KUM61364.1 - 2.9e-24 85.5 0.0 1.3e-23 83.4 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase p450 PF00067.17 KUM61365.1 - 6.9e-15 54.5 0.0 9e-15 54.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF433 PF04255.9 KUM61365.1 - 0.11 11.8 0.0 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF433) LRR_4 PF12799.2 KUM61366.1 - 6.1e-40 134.2 31.1 4.2e-10 39.0 0.9 7.4 3 2 5 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KUM61366.1 - 1.4e-21 75.9 49.5 9.7e-08 31.6 1.4 5.4 3 1 4 7 7 7 7 Leucine rich repeat LRR_1 PF00560.28 KUM61366.1 - 3.1e-14 50.8 27.9 0.13 12.4 0.5 10.7 10 2 1 11 11 11 5 Leucine Rich Repeat LRR_6 PF13516.1 KUM61366.1 - 2.1e-13 48.8 18.3 0.093 12.8 0.3 10.0 7 3 3 10 10 10 4 Leucine Rich repeat LRR_9 PF14580.1 KUM61366.1 - 4.1e-12 45.9 10.0 2.3e-06 27.2 2.3 4.2 1 1 4 5 5 5 5 Leucine-rich repeat LRR_7 PF13504.1 KUM61366.1 - 1.1e-09 36.8 18.8 0.86 10.0 0.1 9.8 9 2 1 10 10 10 3 Leucine rich repeat NIF PF03031.13 KUM61367.1 - 1.1e-51 174.5 0.1 1.8e-51 173.9 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 KUM61367.1 - 0.13 12.4 0.1 1.2 9.2 0.0 2.1 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase ABC_membrane_2 PF06472.10 KUM61368.1 - 1.6e-91 306.3 0.1 4.2e-91 304.9 0.0 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KUM61368.1 - 2.3e-11 44.1 0.0 4.6e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.1 KUM61368.1 - 0.032 14.5 2.1 3.5 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KUM61368.1 - 0.037 13.5 0.0 0.19 11.2 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain RuvB_N PF05496.7 KUM61368.1 - 0.18 10.8 0.0 0.5 9.3 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Clr2 PF10383.4 KUM61369.1 - 4.1e-26 91.6 0.0 6.5e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 Grp1_Fun34_YaaH PF01184.14 KUM61370.1 - 1.5e-83 279.2 14.5 1.7e-83 279.0 10.0 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family 2OG-FeII_Oxy PF03171.15 KUM61371.1 - 0.026 14.7 0.0 0.064 13.5 0.0 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Peptidase_M24 PF00557.19 KUM61372.1 - 2.3e-39 135.1 0.0 2.8e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 KUM61372.1 - 0.0013 18.5 5.4 0.0034 17.2 3.7 1.7 1 0 0 1 1 1 1 MYND finger Acyl_transf_2 PF02273.10 KUM61372.1 - 0.15 11.0 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Acyl transferase Peptidase_M24 PF00557.19 KUM61373.1 - 3.4e-37 128.0 0.2 4.7e-37 127.5 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF2439 PF10382.4 KUM61374.1 - 1e-06 28.8 0.0 1.6e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) MFS_1 PF07690.11 KUM61375.1 - 3.7e-24 85.1 16.9 3.7e-24 85.1 11.7 2.2 3 0 0 3 3 3 1 Major Facilitator Superfamily HR1 PF02185.11 KUM61376.1 - 0.048 13.3 0.4 0.06 13.0 0.3 1.2 1 0 0 1 1 1 0 Hr1 repeat Cupin_2 PF07883.6 KUM61377.1 - 4.7e-07 29.2 0.0 6e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Cupin domain DUF4437 PF14499.1 KUM61377.1 - 0.024 13.5 0.0 0.029 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) MFS_1 PF07690.11 KUM61378.1 - 2.9e-23 82.1 23.9 6.9e-23 80.9 16.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1147 PF06615.6 KUM61379.1 - 0.084 12.7 1.5 0.22 11.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1147) Amidase PF01425.16 KUM61380.1 - 1e-92 311.3 0.0 1.2e-92 311.1 0.0 1.1 1 0 0 1 1 1 1 Amidase SnoaL_2 PF12680.2 KUM61382.1 - 0.00018 21.8 0.0 0.00021 21.6 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 KUM61382.1 - 0.0021 18.0 0.0 0.0027 17.7 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 KUM61382.1 - 0.0054 16.9 0.0 0.0065 16.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_4 PF13577.1 KUM61382.1 - 0.016 15.0 0.0 0.02 14.8 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain Aa_trans PF01490.13 KUM61385.1 - 4e-52 177.0 33.5 4.7e-52 176.8 23.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3139 PF11337.3 KUM61385.1 - 0.4 11.0 2.1 39 4.6 0.1 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3139) zf-Tim10_DDP PF02953.10 KUM61389.1 - 9.8e-26 88.8 0.7 1.1e-25 88.6 0.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 KUM61389.1 - 0.027 13.9 0.7 0.031 13.7 0.5 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) tRNA-synt_2 PF00152.15 KUM61390.1 - 6.7e-25 87.5 0.0 9.5e-25 87.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KUM61390.1 - 1.7e-11 43.8 0.0 3.3e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.1 KUM61390.1 - 0.00049 19.9 0.0 0.037 13.8 0.0 2.0 1 1 1 2 2 2 2 OB-fold nucleic acid binding domain PEP_mutase PF13714.1 KUM61390.1 - 0.028 13.6 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase tRNA-synt_2b PF00587.20 KUM61390.1 - 0.053 13.1 0.0 3.7 7.0 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 KUM61391.1 - 2.8e-32 111.8 0.0 3.1e-32 111.6 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) SICA_C PF12879.2 KUM61392.1 - 9.6e-05 22.2 6.1 0.11 12.3 0.5 2.7 1 1 1 2 2 2 2 SICA C-terminal inner membrane domain DUF2486 PF10667.4 KUM61392.1 - 0.59 10.6 18.2 2.5 8.5 5.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2486) DUF1875 PF08961.5 KUM61392.1 - 7 5.8 8.9 3.5e+02 0.3 6.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1875) AAA PF00004.24 KUM61394.1 - 1.7e-19 70.3 0.1 1.1e-17 64.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KUM61394.1 - 0.00013 22.7 0.1 0.0006 20.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KUM61394.1 - 0.0019 18.3 2.8 4.5 7.4 0.0 3.5 2 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KUM61394.1 - 0.0072 16.3 0.2 0.39 10.6 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.1 KUM61394.1 - 0.011 16.0 0.1 0.042 14.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KUM61394.1 - 0.049 13.3 0.0 0.19 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DEAD PF00270.24 KUM61394.1 - 0.063 12.7 0.4 0.92 8.9 0.0 2.7 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_2 PF07724.9 KUM61394.1 - 0.09 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 KUM61394.1 - 0.092 12.1 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.1 KUM61394.1 - 0.13 12.0 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Myb_DNA-bind_6 PF13921.1 KUM61395.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain HSDR_N_2 PF13588.1 KUM61397.1 - 0.0075 16.0 0.1 0.31 10.8 0.0 2.4 2 0 0 2 2 2 2 Type I restriction enzyme R protein N terminus (HSDR_N) CENP-R PF06729.7 KUM61398.1 - 0.036 13.7 2.8 0.07 12.8 0.1 2.3 2 0 0 2 2 2 0 Kinetochore component, CENP-R APH PF01636.18 KUM61399.1 - 8.4e-05 22.4 0.0 0.00019 21.2 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KUM61403.1 - 5.9e-08 32.0 0.1 8.2e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KUM61403.1 - 1.9e-07 30.4 0.0 2.7e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF3723 PF12520.3 KUM61404.1 - 9.3e-101 337.8 0.2 9.3e-101 337.8 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3723) Ank_2 PF12796.2 KUM61406.1 - 2.9e-51 171.7 19.6 1.6e-21 76.4 2.3 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KUM61406.1 - 1.8e-31 106.3 20.4 1.8e-06 27.4 0.1 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 KUM61406.1 - 4e-27 94.0 4.8 3.8e-07 30.4 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM61406.1 - 9.1e-21 73.4 13.0 8.9e-05 22.6 0.2 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM61406.1 - 7.8e-16 56.6 7.3 0.045 14.0 0.1 5.0 5 0 0 5 5 5 4 Ankyrin repeat SNAP PF14938.1 KUM61406.1 - 0.0006 19.0 1.2 0.026 13.6 0.1 2.0 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP DUF1843 PF08898.5 KUM61406.1 - 0.0041 17.1 16.6 3.1 7.9 2.3 4.5 3 1 0 4 4 4 1 Domain of unknown function (DUF1843) CholecysA-Rec_N PF09193.5 KUM61406.1 - 0.015 15.1 2.3 36 4.3 0.0 3.9 4 0 0 4 4 4 0 Cholecystokinin A receptor, N-terminal DUF3710 PF12502.3 KUM61406.1 - 0.019 14.2 0.9 14 4.9 0.1 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF3710) UPF0051 PF01458.12 KUM61406.1 - 0.03 13.7 6.5 25 4.2 0.1 3.8 3 1 0 4 4 4 0 Uncharacterized protein family (UPF0051) DUF892 PF05974.7 KUM61406.1 - 0.04 13.7 5.5 23 4.7 0.0 4.6 4 1 1 5 5 5 0 Domain of unknown function (DUF892) Aconitase PF00330.15 KUM61406.1 - 0.1 11.0 0.7 24 3.2 0.0 3.5 1 1 4 5 5 5 0 Aconitase family (aconitate hydratase) ApoLp-III PF07464.6 KUM61406.1 - 0.11 12.4 0.1 23 4.9 0.0 2.8 1 1 3 4 4 4 0 Apolipophorin-III precursor (apoLp-III) DUF3396 PF11876.3 KUM61406.1 - 0.39 9.7 3.6 18 4.3 0.0 3.0 1 1 3 4 4 4 0 Protein of unknown function (DUF3396) FMN_dh PF01070.13 KUM61406.1 - 0.85 8.3 6.1 9.1 5.0 0.0 3.1 1 1 3 4 4 4 0 FMN-dependent dehydrogenase Trp_syntA PF00290.15 KUM61407.1 - 6.2e-92 306.7 0.0 1.1e-91 305.9 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 KUM61407.1 - 3.3e-46 157.9 0.7 5.1e-46 157.2 0.5 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ATP-synt_ab PF00006.20 KUM61408.1 - 9.2e-63 211.6 0.0 1.2e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KUM61408.1 - 1.3e-16 61.0 0.0 2.3e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KUM61408.1 - 9.6e-11 41.7 0.5 1.9e-10 40.8 0.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KUM61408.1 - 0.00055 19.7 0.3 0.0011 18.8 0.2 1.5 1 0 0 1 1 1 1 HAS barrel domain Peptidase_S10 PF00450.17 KUM61409.1 - 4.2e-80 269.9 0.6 7.7e-80 269.0 0.4 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase ADH_zinc_N PF00107.21 KUM61411.1 - 4e-26 91.0 0.7 6.2e-26 90.4 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KUM61411.1 - 5.4e-14 53.1 0.1 1.4e-13 51.8 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM61411.1 - 0.00051 19.7 0.0 0.00091 18.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 KUM61411.1 - 0.058 13.3 0.4 0.14 12.0 0.3 1.7 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.1 KUM61411.1 - 0.078 12.9 0.4 0.19 11.7 0.3 1.6 1 1 0 1 1 1 0 NADH(P)-binding DnaJ PF00226.26 KUM61414.1 - 3.1e-19 68.4 0.5 3.1e-19 68.4 0.3 2.5 3 0 0 3 3 3 1 DnaJ domain MBF1 PF08523.5 KUM61414.1 - 0.064 13.2 7.3 0.16 12.0 5.0 1.7 1 0 0 1 1 1 0 Multiprotein bridging factor 1 DUF4316 PF14195.1 KUM61414.1 - 0.58 10.2 8.1 0.33 11.0 3.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4316) TMCO5 PF14992.1 KUM61414.1 - 1.4 8.0 9.7 2.3 7.3 6.7 1.3 1 0 0 1 1 1 0 TMCO5 family DUF4200 PF13863.1 KUM61414.1 - 4.2 7.3 18.3 0.7 9.8 9.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) dCMP_cyt_deam_1 PF00383.17 KUM61415.1 - 7.3e-11 41.6 0.0 2.7e-10 39.8 0.0 1.9 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 KUM61415.1 - 0.0073 15.9 0.0 0.0098 15.5 0.0 1.4 1 1 0 1 1 1 1 APOBEC-like N-terminal domain GYF PF02213.11 KUM61416.1 - 1.2e-17 63.1 0.1 2.6e-17 62.1 0.1 1.6 1 0 0 1 1 1 1 GYF domain Usp PF00582.21 KUM61417.1 - 5.8e-15 55.7 1.6 8.9e-09 35.6 0.0 3.0 2 1 0 2 2 2 2 Universal stress protein family MARVEL PF01284.18 KUM61419.1 - 2.2e-21 76.1 10.7 2.6e-21 75.9 7.4 1.0 1 0 0 1 1 1 1 Membrane-associating domain DUF1206 PF06724.6 KUM61419.1 - 0.02 14.6 0.8 0.066 12.9 0.1 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) adh_short PF00106.20 KUM61420.1 - 1e-21 77.5 2.0 1.4e-21 77.1 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM61420.1 - 4.4e-16 59.0 0.7 6.7e-16 58.4 0.5 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KUM61420.1 - 1e-08 34.4 0.0 1.3e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KUM61420.1 - 1.6e-08 34.3 0.1 3.5e-08 33.1 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KUM61420.1 - 0.0018 18.0 0.4 0.0049 16.6 0.3 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 KUM61420.1 - 0.016 15.1 0.6 0.034 14.1 0.3 1.5 1 1 0 1 1 1 0 NADH(P)-binding Prenyltransf PF01255.14 KUM61421.1 - 1.9e-49 167.7 0.0 2.3e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase HD_5 PF13487.1 KUM61421.1 - 0.11 12.4 0.0 0.46 10.4 0.0 1.9 2 0 0 2 2 2 0 HD domain Stc1 PF12898.2 KUM61422.1 - 5.5e-13 48.7 3.9 8.4e-13 48.1 2.7 1.2 1 0 0 1 1 1 1 Stc1 domain ZZ PF00569.12 KUM61422.1 - 2.1 7.9 8.3 20 4.8 5.7 2.1 1 1 0 1 1 1 0 Zinc finger, ZZ type Pkinase PF00069.20 KUM61423.1 - 5.7e-59 199.3 0.0 8.4e-59 198.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM61423.1 - 5.9e-31 107.4 0.0 3e-29 101.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KUM61423.1 - 0.055 12.2 0.0 0.074 11.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Stn1 PF10451.4 KUM61424.1 - 5.4e-13 48.3 0.3 1.1e-05 24.4 0.0 2.1 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 KUM61424.1 - 5.3e-06 26.2 0.0 0.0063 16.3 0.0 2.4 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain IMD PF08397.6 KUM61424.1 - 0.059 12.6 0.9 0.1 11.9 0.6 1.3 1 0 0 1 1 1 0 IRSp53/MIM homology domain Cytochrom_C PF00034.16 KUM61426.1 - 3.6e-11 43.7 0.0 5.4e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 KUM61426.1 - 3.1e-08 33.6 3.7 2.2e-07 30.9 2.5 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 KUM61426.1 - 0.0002 20.8 0.1 0.00057 19.3 0.1 1.7 2 0 0 2 2 2 1 Cytochrome c-550 domain Haem_bd PF14376.1 KUM61426.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Haem-binding domain Baculo_PEP_C PF04513.7 KUM61427.1 - 0.23 11.2 2.4 0.53 10.1 0.2 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RNase_PH PF01138.16 KUM61428.1 - 4.4e-13 49.6 0.0 1.7e-12 47.7 0.0 2.0 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KUM61428.1 - 0.026 14.4 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Ank_2 PF12796.2 KUM61430.1 - 1.6e-30 105.2 1.9 2.2e-18 66.3 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KUM61430.1 - 5.1e-22 76.5 3.8 2.4e-06 27.0 0.1 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KUM61430.1 - 2.1e-21 75.8 1.2 1.2e-08 35.2 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM61430.1 - 8e-14 51.3 4.3 1.8e-05 24.8 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM61430.1 - 8.5e-11 41.0 0.2 0.0028 17.7 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat DUF1147 PF06615.6 KUM61430.1 - 0.072 12.9 0.1 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1147) Nop14 PF04147.7 KUM61431.1 - 0.016 13.1 2.2 0.018 13.0 1.5 1.0 1 0 0 1 1 1 0 Nop14-like family ARD PF03079.9 KUM61432.1 - 6.2e-46 156.2 0.1 7.5e-46 155.9 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 KUM61432.1 - 1.2e-10 40.6 0.0 2.1e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KUM61432.1 - 1.5e-06 27.9 0.0 2.2e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 KUM61432.1 - 0.0008 18.8 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Cupin Ribosomal_S8 PF00410.14 KUM61435.1 - 0.092 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S8 Pkinase PF00069.20 KUM61436.1 - 4.4e-66 222.6 0.0 5.3e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM61436.1 - 9.3e-28 97.0 0.0 1.2e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM61436.1 - 0.00024 20.1 0.0 0.00037 19.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KUM61436.1 - 0.0097 15.6 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KUM61436.1 - 0.049 12.4 0.0 0.084 11.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 KUM61436.1 - 0.13 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL SUR7 PF06687.7 KUM61437.1 - 0.43 10.1 2.7 0.62 9.5 1.9 1.2 1 0 0 1 1 1 0 SUR7/PalI family DUF2970 PF11174.3 KUM61437.1 - 2.7 7.6 6.2 0.29 10.7 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Abhydrolase_6 PF12697.2 KUM61438.1 - 2e-21 76.9 0.1 2.4e-21 76.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM61438.1 - 1e-08 35.0 0.0 2.4e-08 33.8 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KUM61438.1 - 0.076 13.2 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Aldo_ket_red PF00248.16 KUM61439.1 - 2.1e-46 158.0 0.0 2.4e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GIDA PF01134.17 KUM61441.1 - 5.7e-154 512.7 0.0 7e-154 512.4 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 KUM61441.1 - 5.6e-20 71.1 0.0 1.5e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 KUM61441.1 - 2e-06 27.8 1.0 4.2e-06 26.7 0.7 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KUM61441.1 - 4e-06 26.1 1.2 6.6e-06 25.4 0.8 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KUM61441.1 - 0.00092 18.1 2.0 0.00092 18.1 1.4 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KUM61441.1 - 0.0014 17.6 3.3 0.59 8.9 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 KUM61441.1 - 0.0083 15.7 0.1 0.015 14.8 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 KUM61441.1 - 0.02 13.3 0.7 0.17 10.2 0.3 2.1 2 0 0 2 2 2 0 HI0933-like protein Gti1_Pac2 PF09729.4 KUM61442.1 - 2.3e-62 209.8 0.0 4.6e-62 208.8 0.0 1.5 2 0 0 2 2 2 1 Gti1/Pac2 family DUF2404 PF10296.4 KUM61443.1 - 0.00025 21.1 0.0 0.00046 20.2 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) FAD_binding_4 PF01565.18 KUM61444.1 - 2.3e-18 65.9 1.1 5.4e-18 64.7 0.7 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KUM61444.1 - 4.4e-13 48.9 0.9 1.1e-12 47.6 0.7 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KUM61444.1 - 0.032 13.3 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Epimerase PF01370.16 KUM61445.1 - 3.8e-14 52.7 0.0 8.1e-14 51.6 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KUM61445.1 - 1.1e-12 48.3 0.2 3.1e-12 46.8 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KUM61445.1 - 2.4e-08 33.0 0.0 2.9e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KUM61445.1 - 6e-05 22.4 0.0 8.6e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 KUM61445.1 - 0.0031 16.4 0.0 0.015 14.2 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein F420_oxidored PF03807.12 KUM61445.1 - 0.0033 17.8 0.0 0.0083 16.5 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 KUM61445.1 - 0.0059 15.5 0.0 0.0087 14.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KUM61445.1 - 0.061 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase p450 PF00067.17 KUM61446.1 - 4.2e-58 197.0 0.0 5.3e-58 196.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 KUM61447.1 - 2e-09 37.5 0.2 5.8e-09 36.0 0.0 1.8 2 1 1 3 3 3 1 short chain dehydrogenase Epimerase PF01370.16 KUM61447.1 - 3.6e-05 23.3 0.1 6.5e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KUM61447.1 - 0.00014 21.6 0.1 0.0048 16.5 0.1 2.1 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KUM61447.1 - 0.00017 21.4 0.0 0.00033 20.5 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase p450 PF00067.17 KUM61448.1 - 1.9e-57 194.8 0.0 2e-57 194.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hydantoinase_A PF01968.13 KUM61450.1 - 2.1e-82 276.5 4.1 1.4e-81 273.7 0.7 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydantoinase_B PF02538.9 KUM61450.1 - 1.3e-63 215.0 0.0 2.1e-63 214.3 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydant_A_N PF05378.8 KUM61450.1 - 4.7e-48 163.0 0.2 4e-45 153.4 0.0 2.7 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 KUM61450.1 - 4.6e-05 21.9 3.1 0.089 11.0 0.1 2.8 3 0 0 3 3 3 2 MutL protein FtsA PF14450.1 KUM61450.1 - 0.0023 17.7 0.4 0.21 11.4 0.0 3.4 3 0 0 3 3 3 1 Cell division protein FtsA Ppx-GppA PF02541.11 KUM61450.1 - 0.082 12.0 0.2 0.2 10.8 0.0 1.7 2 0 0 2 2 2 0 Ppx/GppA phosphatase family Mis12 PF05859.7 KUM61450.1 - 0.09 12.5 0.2 6.2 6.6 0.0 3.2 3 0 0 3 3 3 0 Mis12 protein Methyltransf_23 PF13489.1 KUM61451.1 - 1.2e-08 34.8 0.0 1.5e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM61451.1 - 2e-07 30.7 0.0 5e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM61451.1 - 7.4e-07 29.5 0.0 1.4e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM61451.1 - 8.5e-06 26.3 0.0 5.7e-05 23.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM61451.1 - 3.6e-05 24.1 0.0 9.3e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KUM61451.1 - 0.014 14.5 0.0 0.05 12.7 0.0 1.8 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 KUM61451.1 - 0.022 13.7 0.0 2.6 7.0 0.0 2.9 3 0 0 3 3 3 0 Putative methyltransferase Methyltransf_26 PF13659.1 KUM61451.1 - 0.035 14.1 0.0 0.33 11.0 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Trp_DMAT PF11991.3 KUM61452.1 - 9.7e-93 311.2 0.0 1.1e-92 311.0 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Lyase_aromatic PF00221.14 KUM61453.1 - 4.3e-158 526.6 1.2 6.1e-158 526.1 0.8 1.2 1 0 0 1 1 1 1 Aromatic amino acid lyase Glycos_transf_N PF04413.11 KUM61453.1 - 0.098 11.8 0.0 0.27 10.4 0.0 1.7 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) UreF PF01730.11 KUM61454.1 - 2.4e-13 50.4 0.7 5.8e-13 49.1 0.5 1.6 1 1 0 1 1 1 1 UreF BRE1 PF08647.6 KUM61455.1 - 3.7e-27 94.1 8.4 3.7e-27 94.1 5.8 5.6 3 2 2 5 5 3 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 KUM61455.1 - 2.3e-09 37.1 10.0 3.7e-09 36.4 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KUM61455.1 - 1.1e-08 34.5 7.1 1.8e-08 33.8 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KUM61455.1 - 3.6e-08 32.9 10.2 6.3e-08 32.1 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KUM61455.1 - 3.4e-07 29.9 7.0 5.9e-07 29.2 4.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KUM61455.1 - 2.6e-06 27.0 10.3 4.4e-06 26.3 7.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KUM61455.1 - 2.3e-05 24.0 5.8 5.6e-05 22.7 4.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger DUF1272 PF06906.6 KUM61455.1 - 0.0033 17.2 5.7 0.0067 16.2 3.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) zf-C3HC4_4 PF15227.1 KUM61455.1 - 0.0046 16.8 6.6 0.0083 15.9 4.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KUM61455.1 - 0.012 15.1 6.9 0.088 12.4 5.2 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 KUM61455.1 - 0.016 14.7 3.5 0.033 13.7 2.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PLAC9 PF15205.1 KUM61455.1 - 0.027 14.7 0.5 3 8.1 0.0 3.3 4 0 0 4 4 3 0 Placenta-specific protein 9 zf-rbx1 PF12678.2 KUM61455.1 - 0.03 14.4 5.4 0.078 13.0 3.7 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger DUF223 PF02721.9 KUM61455.1 - 0.054 13.5 0.9 0.33 11.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF223 Filament PF00038.16 KUM61455.1 - 0.08 12.3 45.9 48 3.2 24.9 3.8 1 1 1 2 2 2 0 Intermediate filament protein Rad50_zn_hook PF04423.9 KUM61455.1 - 0.081 12.4 4.5 0.67 9.4 0.1 4.2 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-Nse PF11789.3 KUM61455.1 - 0.14 11.7 4.5 0.28 10.7 3.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Reo_sigmaC PF04582.7 KUM61455.1 - 0.16 11.1 30.0 0.06 12.5 2.9 3.8 1 1 3 4 4 4 0 Reovirus sigma C capsid protein zf-ribbon_3 PF13248.1 KUM61455.1 - 0.17 11.1 3.4 0.4 9.9 2.4 1.6 1 1 0 1 1 1 0 zinc-ribbon domain zf-RING_6 PF14835.1 KUM61455.1 - 0.23 11.2 3.8 0.44 10.3 2.6 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-H2C2_2 PF13465.1 KUM61455.1 - 0.27 11.5 2.3 2.9 8.3 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double domain FYVE PF01363.16 KUM61455.1 - 0.28 11.1 11.7 0.4 10.5 4.1 2.5 1 1 1 2 2 2 0 FYVE zinc finger zf-C2HC_2 PF13913.1 KUM61455.1 - 0.57 9.9 5.8 1.7 8.3 1.4 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Myosin_tail_1 PF01576.14 KUM61455.1 - 0.68 7.5 55.3 1.5 6.4 25.6 2.7 1 1 1 2 2 2 0 Myosin tail UPF0547 PF10571.4 KUM61455.1 - 0.91 9.2 6.2 0.76 9.5 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DZR PF12773.2 KUM61455.1 - 2.5 7.9 9.2 6.1 6.7 6.4 1.6 1 1 0 1 1 1 0 Double zinc ribbon zf-FCS PF06467.9 KUM61455.1 - 2.9 7.6 8.7 7.3 6.3 0.1 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif HALZ PF02183.13 KUM61455.1 - 3.1 7.5 20.7 2.6 7.8 0.7 5.9 6 0 0 6 6 5 0 Homeobox associated leucine zipper Sec8_exocyst PF04048.9 KUM61455.1 - 7.8 6.1 28.0 0.063 12.9 3.5 4.3 2 1 3 6 6 6 0 Sec8 exocyst complex component specific domain Prefoldin_2 PF01920.15 KUM61456.1 - 0.29 10.9 2.9 4.4 7.1 0.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit Myb_DNA-binding PF00249.26 KUM61457.1 - 0.00052 20.0 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF1183 PF06682.7 KUM61458.1 - 2.3e-95 319.8 1.1 3.2e-95 319.3 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) XFP_C PF09363.5 KUM61458.1 - 0.053 12.9 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 XFP C-terminal domain Lipoxygenase PF00305.14 KUM61459.1 - 1e-16 60.1 0.0 1e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Lipoxygenase Lipoxygenase PF00305.14 KUM61460.1 - 6.7e-19 67.3 1.1 5.5e-18 64.3 0.8 2.2 1 1 0 1 1 1 1 Lipoxygenase NMD3 PF04981.8 KUM61461.1 - 4.9e-71 238.5 6.0 6.8e-71 238.1 4.1 1.2 1 0 0 1 1 1 1 NMD3 family DUF1003 PF06210.6 KUM61461.1 - 1.4 8.8 5.1 3.7 7.5 3.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) DZR PF12773.2 KUM61461.1 - 7.1 6.5 11.6 20 5.1 5.6 2.8 2 1 0 2 2 2 0 Double zinc ribbon HypA PF01155.14 KUM61461.1 - 7.6 6.2 8.5 6.4 6.4 0.0 2.8 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family Fungal_trans_2 PF11951.3 KUM61463.1 - 1.5e-05 23.8 0.1 1.5e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1889 PF08986.5 KUM61463.1 - 0.073 13.2 0.0 0.098 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1889) Pyr_redox_3 PF13738.1 KUM61464.1 - 0.0025 17.8 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KUM61464.1 - 0.026 14.3 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KUM61464.1 - 0.046 12.7 0.0 0.81 8.6 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.1 KUM61464.1 - 0.078 13.0 0.3 0.17 11.9 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Mannosyl_trans3 PF11051.3 KUM61465.1 - 2.2e-78 263.3 0.0 8.6e-78 261.3 0.0 1.8 1 1 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 KUM61465.1 - 0.17 11.1 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 8 EF-hand_6 PF13405.1 KUM61466.1 - 7.8e-06 25.3 0.0 1.5e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.27 KUM61466.1 - 1.1e-05 24.3 0.0 1.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 KUM61466.1 - 1.7e-05 23.9 0.2 3.1e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KUM61466.1 - 0.00024 21.1 0.0 0.00028 20.9 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 KUM61466.1 - 0.09 12.4 0.1 0.16 11.6 0.1 1.5 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.27 KUM61467.1 - 8e-19 65.4 13.5 9.9e-08 30.7 0.8 3.1 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 KUM61467.1 - 1e-13 51.1 6.0 4.4e-12 45.9 0.9 2.2 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KUM61467.1 - 3.8e-13 48.1 6.1 3.5e-05 23.3 0.1 3.2 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 KUM61467.1 - 4.9e-13 47.7 8.3 5.6e-06 25.4 0.4 3.3 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 KUM61467.1 - 1.6e-11 43.6 10.1 2.9e-05 23.5 1.0 3.2 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KUM61467.1 - 6.9e-05 22.8 0.0 8.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KUM61467.1 - 0.00014 21.5 7.0 0.11 12.3 0.5 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Anthrax-tox_M PF09156.5 KUM61467.1 - 0.015 14.4 0.1 0.019 14.0 0.1 1.1 1 0 0 1 1 1 0 Anthrax toxin lethal factor, middle domain EF-hand_9 PF14658.1 KUM61467.1 - 0.03 14.2 0.1 0.25 11.2 0.1 2.1 1 1 1 2 2 2 0 EF-hand domain ATP-cone PF03477.11 KUM61467.1 - 0.038 14.4 0.3 0.061 13.7 0.2 1.3 1 0 0 1 1 1 0 ATP cone domain Fungal_trans_2 PF11951.3 KUM61468.1 - 3.1e-49 167.6 1.9 3.5e-49 167.4 1.3 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain CIAPIN1 PF05093.8 KUM61469.1 - 0.29 11.2 0.0 0.29 11.2 0.0 2.3 2 1 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Aminotran_1_2 PF00155.16 KUM61471.1 - 4.5e-38 131.1 0.0 7e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KUM61471.1 - 2.8e-07 29.9 0.0 4.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 KUM61471.1 - 3.1e-05 22.4 0.0 4.7e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KUM61471.1 - 7.9e-05 21.5 0.0 0.00012 20.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KUM61471.1 - 0.0017 17.5 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Metallothio_11 PF02066.10 KUM61471.1 - 0.048 13.5 0.1 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Metallothionein family 11 Peptidase_M22 PF00814.20 KUM61472.1 - 1.1e-85 287.4 0.0 1.2e-85 287.2 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family AMPKBI PF04739.10 KUM61473.1 - 3.7e-28 97.3 0.0 3.7e-28 97.3 0.0 2.5 3 0 0 3 3 3 1 5'-AMP-activated protein kinase beta subunit, interation domain SET PF00856.23 KUM61474.1 - 2e-18 67.1 0.0 1.2e-17 64.6 0.0 2.1 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 KUM61474.1 - 0.00075 19.4 0.1 0.0025 17.7 0.0 2.0 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Ribosomal_60s PF00428.14 KUM61475.1 - 0.09 13.1 18.3 0.32 11.4 0.2 3.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein adh_short PF00106.20 KUM61477.1 - 8.3e-18 64.8 2.9 1.7e-17 63.8 2.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KUM61477.1 - 1.9e-08 34.0 0.2 2.3e-07 30.4 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KUM61477.1 - 9.9e-08 31.8 1.0 1.8e-07 31.0 0.7 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KUM61477.1 - 0.00096 19.1 2.4 0.0024 17.9 1.6 1.7 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KUM61477.1 - 0.0024 17.1 0.3 0.0036 16.5 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 KUM61477.1 - 0.0038 15.9 0.0 0.0065 15.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.1 KUM61477.1 - 0.0077 16.0 1.2 0.014 15.2 0.5 1.6 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase TrkA_N PF02254.13 KUM61477.1 - 0.018 15.0 1.8 0.031 14.2 1.1 1.7 1 1 0 1 1 1 0 TrkA-N domain ATLF PF07737.6 KUM61477.1 - 0.068 12.5 0.0 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 Anthrax toxin lethal factor, N- and C-terminal domain Glyoxalase_2 PF12681.2 KUM61478.1 - 4e-07 30.6 0.0 5e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KUM61478.1 - 3.5e-05 23.7 0.0 4.5e-05 23.4 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Ank_2 PF12796.2 KUM61479.1 - 7.9e-85 279.3 29.3 1.8e-19 69.8 0.5 5.6 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 KUM61479.1 - 6.6e-43 142.4 22.3 8.5e-05 22.1 0.1 9.9 8 1 1 9 9 9 9 Ankyrin repeat Ank_3 PF13606.1 KUM61479.1 - 1.8e-32 108.1 17.2 0.001 19.1 0.0 10.4 9 1 1 10 10 10 9 Ankyrin repeat Ank_5 PF13857.1 KUM61479.1 - 2.4e-31 107.0 13.9 0.0058 16.8 0.0 9.7 7 2 2 9 9 9 8 Ankyrin repeats (many copies) Ank_4 PF13637.1 KUM61479.1 - 9.9e-27 92.8 6.9 1.2e-07 32.0 0.0 6.4 3 1 3 6 6 6 6 Ankyrin repeats (many copies) NACHT PF05729.7 KUM61479.1 - 2.2e-06 27.4 0.0 4.6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain UPF0079 PF02367.12 KUM61479.1 - 0.016 14.7 0.0 0.042 13.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 KAP_NTPase PF07693.9 KUM61479.1 - 0.084 11.8 0.1 0.93 8.4 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain DUF3447 PF11929.3 KUM61479.1 - 0.091 12.5 0.0 20 5.0 0.0 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF3447) AAA_14 PF13173.1 KUM61479.1 - 0.14 12.0 0.0 1.2 9.0 0.0 2.4 1 1 0 1 1 1 0 AAA domain DUF4066 PF13278.1 KUM61480.1 - 9e-27 93.3 0.0 1.1e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KUM61480.1 - 4.5e-15 55.3 0.0 6.3e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Fungal_trans PF04082.13 KUM61481.1 - 2.7e-06 26.4 0.8 6.9e-06 25.1 0.6 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC1 PF03109.11 KUM61482.1 - 2.3e-34 117.9 0.0 7e-34 116.3 0.0 1.9 2 0 0 2 2 2 1 ABC1 family GrpB PF04229.9 KUM61483.1 - 5.2e-46 156.3 0.0 6.6e-46 156.0 0.0 1.1 1 0 0 1 1 1 1 GrpB protein EPL1 PF10513.4 KUM61484.1 - 1.9e-32 112.7 0.7 1.9e-32 112.7 0.5 3.1 3 1 0 3 3 3 1 Enhancer of polycomb-like SET PF00856.23 KUM61487.1 - 7.6e-13 49.0 0.0 1.9e-11 44.5 0.0 2.6 1 1 0 1 1 1 1 SET domain TPR_11 PF13414.1 KUM61487.1 - 2.7e-11 42.9 0.4 5.9e-09 35.4 0.0 3.1 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 KUM61487.1 - 3.9e-07 29.4 0.0 0.34 10.9 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 KUM61487.1 - 2.5e-06 26.8 0.0 0.0024 17.4 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KUM61487.1 - 0.0021 18.5 0.1 8.5 7.3 0.1 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KUM61487.1 - 0.0035 17.4 0.3 0.012 15.6 0.2 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KUM61487.1 - 0.0035 17.9 0.3 5.3 7.8 0.3 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KUM61487.1 - 0.0061 16.4 0.6 2.4 8.1 0.0 3.3 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KUM61487.1 - 0.012 15.4 0.4 7.4 6.6 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 KUM61487.1 - 0.055 13.2 0.1 2.9 7.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KUM61487.1 - 0.098 13.1 0.0 6 7.5 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1857 PF08982.6 KUM61488.1 - 1.4e-40 138.2 0.0 1.6e-40 138.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) SAS4 PF15460.1 KUM61489.1 - 1.3e-31 108.4 8.2 3.1e-31 107.2 5.7 1.6 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 PEHE PF15275.1 KUM61489.1 - 0.01 16.2 0.3 0.01 16.2 0.2 4.7 4 2 0 4 4 4 0 PEHE domain Acetyltransf_4 PF13420.1 KUM61490.1 - 6.4e-08 32.6 0.0 3.6e-05 23.7 0.0 2.3 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KUM61490.1 - 0.0063 16.6 0.0 0.0099 16.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HAT PF02184.11 KUM61491.1 - 0.02 14.6 0.1 0.053 13.2 0.1 1.7 1 0 0 1 1 1 0 HAT (Half-A-TPR) repeat DUF2156 PF09924.4 KUM61492.1 - 1.5e-29 102.8 0.0 2.2e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) Ribosomal_60s PF00428.14 KUM61493.1 - 1.4 9.3 7.3 2.9 8.3 5.0 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Ribonuc_L-PSP PF01042.16 KUM61494.1 - 2.2e-18 66.1 0.0 2.9e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP DZR PF12773.2 KUM61495.1 - 0.00014 21.5 2.8 0.00034 20.3 1.9 1.7 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 KUM61495.1 - 0.00045 19.3 5.2 0.00045 19.3 3.6 2.3 2 1 1 3 3 3 2 zinc-ribbon domain zinc_ribbon_2 PF13240.1 KUM61495.1 - 0.0018 17.7 8.3 0.1 12.1 5.7 2.7 1 1 1 2 2 2 2 zinc-ribbon domain zf-NADH-PPase PF09297.6 KUM61495.1 - 0.0039 16.6 6.0 0.2 11.2 1.2 2.5 2 0 0 2 2 2 2 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.1 KUM61495.1 - 0.0067 16.0 8.1 0.18 11.5 0.4 2.6 1 1 1 2 2 2 2 Nudix N-terminal EphA2_TM PF14575.1 KUM61495.1 - 0.033 14.5 0.0 0.095 13.1 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF1469 PF07332.6 KUM61495.1 - 0.047 13.4 0.5 1.5 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) RRN7 PF11781.3 KUM61495.1 - 0.1 12.1 4.0 1.3 8.5 0.3 2.5 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF1272 PF06906.6 KUM61495.1 - 0.17 11.7 1.7 0.39 10.6 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) UPF0547 PF10571.4 KUM61495.1 - 0.69 9.6 5.1 6.1 6.6 3.5 2.3 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 YhfH PF14149.1 KUM61495.1 - 0.7 9.7 3.9 1.2 8.9 0.2 2.3 1 1 1 2 2 2 0 YhfH-like protein DUF805 PF05656.9 KUM61495.1 - 0.71 9.7 2.9 9.3 6.1 2.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF805) NOB1_Zn_bind PF08772.6 KUM61495.1 - 8.8 6.2 7.5 4.9 7.0 3.1 2.1 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like AA_permease_2 PF13520.1 KUM61496.1 - 2.1e-44 151.7 41.2 2.6e-44 151.4 28.6 1.0 1 0 0 1 1 1 1 Amino acid permease PAS_9 PF13426.1 KUM61497.1 - 4e-20 72.1 0.0 9e-17 61.3 0.0 3.0 3 0 0 3 3 3 2 PAS domain PAS PF00989.19 KUM61497.1 - 7.5e-05 22.4 0.0 0.00067 19.4 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 KUM61497.1 - 0.037 14.0 0.0 1.7 8.7 0.0 2.6 2 0 0 2 2 2 0 PAS fold Pal1 PF08316.6 KUM61498.1 - 7.4e-10 39.4 0.1 1.6e-09 38.3 0.1 1.7 1 0 0 1 1 1 1 Pal1 cell morphology protein HVSL PF09749.4 KUM61499.1 - 4.9e-78 261.4 0.0 5.6e-78 261.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein Aa_trans PF01490.13 KUM61500.1 - 2.6e-39 134.8 39.4 3.1e-39 134.6 27.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3807 PF12720.2 KUM61501.1 - 2.3e-40 138.5 9.8 2.7e-40 138.3 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) CDC45 PF02724.9 KUM61501.1 - 2.2 6.2 7.5 2.3 6.1 5.2 1.1 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.11 KUM61503.1 - 3.8e-13 48.8 47.7 7.5e-07 28.1 14.4 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily SpoVAB PF13782.1 KUM61503.1 - 1.2 9.1 7.0 0.13 12.2 1.0 2.4 2 1 1 3 3 3 0 Stage V sporulation protein AB Ferritin_2 PF13668.1 KUM61504.1 - 2e-09 37.5 0.0 2.8e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain Peptidase_S10 PF00450.17 KUM61505.1 - 3e-90 303.3 0.1 4.1e-90 302.9 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Glyco_hydro_3 PF00933.16 KUM61507.1 - 6.7e-89 297.8 0.0 9.5e-89 297.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KUM61507.1 - 7.6e-62 208.7 1.0 1.1e-61 208.2 0.3 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KUM61507.1 - 2.8e-27 94.4 0.0 5.8e-27 93.4 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF3828 PF12883.2 KUM61508.1 - 0.005 16.7 0.1 0.0071 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3828) HlyIII PF03006.15 KUM61509.1 - 2.3e-39 135.1 12.1 2.6e-39 134.9 8.4 1.0 1 0 0 1 1 1 1 Haemolysin-III related SnAC PF14619.1 KUM61509.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex Lipase_GDSL PF00657.17 KUM61510.1 - 6e-14 52.4 0.2 8.7e-14 51.9 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KUM61510.1 - 3.7e-13 49.9 0.0 5e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 KUM61510.1 - 0.0033 17.1 0.1 0.011 15.4 0.1 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family GspL_C PF12693.2 KUM61510.1 - 0.0054 16.4 0.0 0.024 14.4 0.0 2.0 2 0 0 2 2 2 1 GspL periplasmic domain ATP-grasp_2 PF08442.5 KUM61511.1 - 1.5e-49 168.1 0.0 2.1e-49 167.6 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 KUM61511.1 - 8.8e-08 31.8 0.1 2.6e-07 30.3 0.0 1.7 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.1 KUM61511.1 - 3.9e-06 26.2 0.0 9.2e-06 25.0 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 KUM61511.1 - 0.0093 15.2 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain DUF303 PF03629.13 KUM61511.1 - 0.018 14.2 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF303) Ligase_CoA PF00549.14 KUM61512.1 - 0.00077 19.0 0.2 0.00086 18.9 0.1 1.1 1 0 0 1 1 1 1 CoA-ligase RRM_1 PF00076.17 KUM61514.1 - 4.5e-25 87.0 0.0 5.3e-25 86.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM61514.1 - 7.2e-20 70.7 0.0 8.4e-20 70.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM61514.1 - 2.2e-14 53.0 0.0 2.7e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KUM61514.1 - 0.0028 17.4 0.0 0.0034 17.2 0.0 1.1 1 0 0 1 1 1 1 RNA binding motif Limkain-b1 PF11608.3 KUM61514.1 - 0.028 14.1 0.1 0.038 13.7 0.1 1.4 1 1 0 1 1 1 0 Limkain b1 DUF1877 PF08974.5 KUM61514.1 - 0.087 12.4 0.0 0.096 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) Nup35_RRM_2 PF14605.1 KUM61514.1 - 0.088 12.5 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Gelsolin PF00626.17 KUM61516.1 - 2.7e-38 129.5 0.7 1.1e-13 50.7 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat DUF3132 PF11330.3 KUM61516.1 - 0.065 13.0 0.1 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3132) NAD_binding_4 PF07993.7 KUM61518.1 - 3.4e-31 108.0 0.0 5.1e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KUM61518.1 - 3.9e-31 107.8 0.0 9.1e-31 106.6 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KUM61518.1 - 1.2e-11 44.5 0.0 2.6e-11 43.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KUM61518.1 - 4.3e-08 33.2 0.0 4.8e-07 29.9 0.0 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.10 KUM61518.1 - 0.0024 16.8 0.0 0.0043 16.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 KUM61518.1 - 0.0031 17.1 0.0 1.9 8.1 0.0 2.5 2 0 0 2 2 2 2 KR domain 3Beta_HSD PF01073.14 KUM61518.1 - 0.0063 15.2 0.0 0.027 13.1 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KUM61518.1 - 0.0065 16.3 0.0 0.17 11.7 0.0 2.6 3 0 0 3 3 3 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KUM61518.1 - 0.013 15.5 0.0 0.033 14.1 0.0 1.8 1 0 0 1 1 1 0 NADH(P)-binding RmlD_sub_bind PF04321.12 KUM61518.1 - 0.035 12.9 0.0 0.57 9.0 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain AP_endonuc_2 PF01261.19 KUM61519.1 - 1e-22 80.5 0.5 1.5e-22 79.9 0.4 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Methyltransf_2 PF00891.13 KUM61521.1 - 2e-27 95.9 0.0 4.2e-27 94.8 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 KUM61521.1 - 0.14 11.9 0.9 0.49 10.2 0.6 2.0 1 1 0 1 1 1 0 Dimerisation domain BcrAD_BadFG PF01869.15 KUM61522.1 - 1.2e-11 44.4 3.5 6.2e-11 42.1 1.6 2.4 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family SIS_2 PF13580.1 KUM61522.1 - 0.00047 19.8 0.0 0.0023 17.6 0.0 2.2 1 1 0 1 1 1 1 SIS domain SIS PF01380.17 KUM61522.1 - 0.015 14.9 0.3 0.097 12.2 0.0 2.4 2 0 0 2 2 2 0 SIS domain DUF1193 PF06702.7 KUM61522.1 - 0.064 12.6 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1193) MFS_1 PF07690.11 KUM61523.1 - 2.6e-16 59.2 36.3 2.6e-16 59.2 25.2 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 KUM61523.1 - 4.6e-09 35.9 3.6 4.6e-09 35.9 2.5 3.2 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 CN_hydrolase PF00795.17 KUM61527.1 - 5.1e-34 117.2 0.1 6.9e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CIA30 PF08547.7 KUM61528.1 - 4.5e-35 120.8 0.0 5.7e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Glyco_hydro_76 PF03663.9 KUM61529.1 - 3.8e-139 464.1 26.6 4.8e-139 463.8 18.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 MFS_1 PF07690.11 KUM61530.1 - 7.2e-45 153.2 22.6 7.2e-45 153.2 15.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM61530.1 - 0.00086 17.6 5.5 0.0017 16.6 3.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF21 PF01595.15 KUM61530.1 - 9.4 5.4 10.0 18 4.5 0.1 3.2 3 1 0 3 3 3 0 Domain of unknown function DUF21 MFS_1 PF07690.11 KUM61531.1 - 1.3e-36 126.1 48.3 1.3e-36 126.1 33.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM61531.1 - 2.8e-08 32.7 18.3 2.8e-08 32.7 12.7 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter adh_short PF00106.20 KUM61532.1 - 1.5e-13 51.0 0.1 2.7e-13 50.1 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KUM61532.1 - 5.1e-05 23.3 0.2 8.7e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KUM61532.1 - 0.00016 21.3 0.0 0.0003 20.5 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM61532.1 - 0.054 12.9 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ribosomal_L12 PF00542.14 KUM61532.1 - 0.083 12.9 0.1 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain Aldo_ket_red PF00248.16 KUM61533.1 - 3.7e-66 222.8 0.0 4.2e-66 222.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.13 KUM61534.1 - 8.8e-07 28.0 0.0 1.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF867 PF05908.6 KUM61534.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF867) COesterase PF00135.23 KUM61535.1 - 1.7e-89 300.9 0.1 1.9e-89 300.7 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KUM61535.1 - 2.2e-08 33.9 0.1 4e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KUM61535.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family F-box PF00646.28 KUM61536.1 - 0.0044 16.6 0.1 0.017 14.7 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KUM61536.1 - 0.027 14.1 0.1 0.07 12.8 0.1 1.7 1 0 0 1 1 1 0 F-box-like Methyltransf_2 PF00891.13 KUM61538.1 - 1.3e-06 27.7 0.0 2.1e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 KUM61538.1 - 0.00041 20.1 0.6 0.0014 18.3 0.3 2.1 2 0 0 2 2 2 1 Dimerisation domain HTH_27 PF13463.1 KUM61538.1 - 0.089 13.1 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain Methyltransf_2 PF00891.13 KUM61539.1 - 1.1e-12 47.7 0.2 1.2e-12 47.5 0.2 1.0 1 0 0 1 1 1 1 O-methyltransferase DUF3533 PF12051.3 KUM61540.1 - 0.16 10.6 9.3 0.24 10.0 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) NUC194 PF08163.7 KUM61540.1 - 0.84 8.4 6.1 1.2 7.8 4.3 1.2 1 0 0 1 1 1 0 NUC194 domain FAM60A PF15396.1 KUM61540.1 - 2 8.1 9.7 0.55 9.9 2.8 2.2 2 0 0 2 2 2 0 Protein Family FAM60A SPATIAL PF15256.1 KUM61540.1 - 4.1 7.4 13.6 0.14 12.1 4.5 1.9 2 0 0 2 2 2 0 SPATIAL Glyco_hydro_71 PF03659.9 KUM61541.1 - 6.2e-145 482.5 2.8 7.4e-145 482.2 1.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.1 KUM61541.1 - 0.17 11.5 0.3 0.37 10.4 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) MR_MLE_C PF13378.1 KUM61543.1 - 1.1e-32 112.3 0.0 1.8e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 KUM61543.1 - 4.6e-19 68.5 0.0 8.5e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 KUM61543.1 - 4.5e-10 39.9 0.0 1e-09 38.7 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain DUF1990 PF09348.5 KUM61543.1 - 0.0098 15.5 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1990) MAAL_C PF07476.6 KUM61543.1 - 0.089 11.7 0.1 0.34 9.8 0.0 1.8 2 1 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus FMN_dh PF01070.13 KUM61544.1 - 2.6e-112 375.2 0.1 4e-112 374.5 0.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KUM61544.1 - 5.5e-23 80.5 0.0 5.3e-22 77.4 0.0 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KUM61544.1 - 2.7e-06 26.5 0.0 5.2e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KUM61544.1 - 1.6e-05 23.9 0.5 0.00014 20.8 0.1 2.3 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.16 KUM61544.1 - 0.0095 14.9 0.1 0.018 14.0 0.0 1.4 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.16 KUM61544.1 - 0.049 12.8 0.1 0.93 8.7 0.0 2.3 2 1 0 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.9 KUM61544.1 - 0.051 12.6 0.1 7.1 5.6 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG ApbA PF02558.11 KUM61545.1 - 2.8e-36 124.2 0.1 3.6e-36 123.8 0.1 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KUM61545.1 - 1.5e-30 105.7 0.0 2.2e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_Gly3P_dh_N PF01210.18 KUM61545.1 - 0.0065 16.2 0.1 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.16 KUM61545.1 - 0.032 14.0 0.1 0.082 12.7 0.0 1.7 1 1 0 1 1 1 0 ThiF family DUF3433 PF11915.3 KUM61546.1 - 1.7e-46 156.3 15.3 4.7e-24 84.3 2.3 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) TauD PF02668.11 KUM61547.1 - 5.5e-49 167.1 0.0 7e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 KUM61548.1 - 2.2e-18 66.1 23.5 3.6e-18 65.4 15.9 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TMEM154 PF15102.1 KUM61548.1 - 0.12 12.0 0.1 21 4.8 0.0 3.0 3 0 0 3 3 3 0 TMEM154 protein family Peptidase_M10 PF00413.19 KUM61548.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Matrixin Glyco_hydro_2 PF00703.16 KUM61549.1 - 1.2e-12 48.2 0.8 2.1e-11 44.2 0.0 2.8 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 KUM61549.1 - 1.6e-07 31.0 0.0 3.2e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Big_5 PF13205.1 KUM61549.1 - 0.059 13.9 0.9 0.29 11.7 0.2 2.4 2 0 0 2 2 2 0 Bacterial Ig-like domain Cyclin PF08613.6 KUM61550.1 - 5.8e-16 59.2 0.0 8.6e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KUM61550.1 - 0.00055 19.5 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain TT_ORF2 PF02957.10 KUM61550.1 - 2.7 8.7 10.7 0.28 11.8 1.5 2.9 3 0 0 3 3 3 0 TT viral ORF2 DNA_pol_A_exo1 PF01612.15 KUM61551.1 - 1.9e-41 141.4 0.1 3.6e-41 140.5 0.1 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 KUM61551.1 - 8.4e-27 93.3 0.1 2.6e-26 91.7 0.1 1.9 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 KUM61551.1 - 3.1e-10 39.6 0.2 1e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 HRDC domain RasGAP PF00616.14 KUM61552.1 - 6.1e-56 189.2 0.0 1.8e-55 187.7 0.0 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 KUM61552.1 - 7e-32 110.0 1.0 7e-32 110.0 0.7 2.3 2 0 0 2 2 2 1 RasGAP C-terminus CD36 PF01130.16 KUM61552.1 - 0.067 11.4 0.1 0.13 10.5 0.1 1.4 1 0 0 1 1 1 0 CD36 family DUF972 PF06156.8 KUM61552.1 - 0.64 10.3 5.4 17 5.8 0.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) SGL PF08450.7 KUM61553.1 - 9.2e-08 31.7 0.3 1.1e-06 28.2 0.2 2.0 1 1 1 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region SUKH-4 PF14435.1 KUM61553.1 - 0.043 13.5 0.1 0.076 12.7 0.1 1.3 1 0 0 1 1 1 0 SUKH-4 immunity protein NHL PF01436.16 KUM61553.1 - 0.24 11.4 1.4 4.2 7.5 0.1 3.0 3 1 0 3 3 3 0 NHL repeat Acetyltransf_1 PF00583.19 KUM61554.1 - 8.3e-15 54.5 0.0 6.2e-10 38.9 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KUM61554.1 - 2.3e-10 40.4 0.0 6.9e-10 38.9 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KUM61554.1 - 5e-10 39.5 0.0 1.4e-06 28.3 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 KUM61554.1 - 6.3e-08 32.2 0.0 0.0019 17.9 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_3 PF13302.1 KUM61554.1 - 1.5e-07 31.6 0.0 2e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KUM61554.1 - 1.2e-05 25.1 0.8 5.7e-05 22.9 0.1 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KUM61554.1 - 0.00047 19.9 0.0 0.00092 19.0 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 KUM61554.1 - 0.0014 18.5 0.0 1.2 8.9 0.0 2.3 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 KUM61554.1 - 0.067 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LCAT PF02450.10 KUM61555.1 - 4.7e-97 325.4 0.0 5.6e-97 325.1 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.13 KUM61555.1 - 0.017 14.4 0.1 0.038 13.3 0.1 1.5 1 0 0 1 1 1 0 Lipase (class 2) BAAT_C PF08840.6 KUM61555.1 - 0.036 13.7 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_5 PF12695.2 KUM61555.1 - 0.052 13.2 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family ATP-synt_F6 PF05511.6 KUM61555.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 DUF900 PF05990.7 KUM61555.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PAP2 PF01569.16 KUM61556.1 - 1.1e-14 54.2 5.9 1.1e-14 54.2 4.1 1.8 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 KUM61556.1 - 4.5e-07 29.5 5.1 1e-06 28.4 3.5 1.6 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 KUM61556.1 - 1 9.6 7.7 0.72 10.1 3.0 2.4 2 0 0 2 2 2 0 PAP2 superfamily C-terminal CRAL_TRIO PF00650.15 KUM61557.1 - 2.3e-36 124.6 0.0 3.2e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KUM61557.1 - 4.6e-11 42.6 0.5 1.8e-10 40.8 0.4 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KUM61557.1 - 1.4e-05 25.0 0.0 3.4e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain DUF1825 PF08855.5 KUM61557.1 - 0.2 11.7 0.7 4.1 7.4 0.1 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF1825) Mis14 PF08641.7 KUM61558.1 - 7.1e-30 103.8 4.9 1.7e-29 102.6 2.9 2.0 2 0 0 2 2 2 1 Kinetochore protein Mis14 like SlyX PF04102.7 KUM61558.1 - 0.24 11.7 2.6 0.74 10.2 1.8 1.8 1 0 0 1 1 1 0 SlyX TEX19 PF15553.1 KUM61558.1 - 0.3 10.9 6.1 0.57 10.0 4.2 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 PI3K_1B_p101 PF10486.4 KUM61558.1 - 0.5 7.8 2.4 0.68 7.4 1.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pox_Ag35 PF03286.9 KUM61558.1 - 0.96 8.9 6.0 1.5 8.3 4.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Pex24p PF06398.6 KUM61559.1 - 3.6e-06 26.0 10.6 5.5e-06 25.4 7.3 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PPR_3 PF13812.1 KUM61560.1 - 0.00045 20.2 0.3 0.009 16.2 0.1 3.3 3 0 0 3 3 3 1 Pentatricopeptide repeat domain Tetraspannin PF00335.15 KUM61563.1 - 0.12 11.6 3.1 0.18 11.0 2.2 1.2 1 0 0 1 1 1 0 Tetraspanin family PQ-loop PF04193.9 KUM61564.1 - 6.1e-38 128.1 11.3 2.5e-19 68.5 0.3 2.5 2 0 0 2 2 2 2 PQ loop repeat V_ATPase_I PF01496.14 KUM61564.1 - 0.076 10.8 0.0 0.098 10.4 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MtN3_slv PF03083.11 KUM61564.1 - 0.11 12.3 6.5 0.26 11.1 0.0 2.5 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange RVT_1 PF00078.22 KUM61565.1 - 1.2e-31 109.8 0.0 1.7e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3435 PF11917.3 KUM61566.1 - 5.1e-148 493.2 0.0 6.6e-148 492.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) MxiH PF09392.5 KUM61566.1 - 0.23 12.0 0.9 0.55 10.8 0.1 2.0 2 0 0 2 2 2 0 Type III secretion needle MxiH like zf-C2H2 PF00096.21 KUM61566.1 - 0.81 10.1 5.8 0.62 10.5 0.5 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF4200 PF13863.1 KUM61567.1 - 0.0041 17.0 13.6 0.0065 16.4 9.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) Transposase_22 PF02994.9 KUM61567.1 - 0.024 13.1 7.2 0.029 12.8 5.0 1.1 1 0 0 1 1 1 0 L1 transposable element Filament PF00038.16 KUM61567.1 - 0.078 12.4 9.8 0.096 12.1 6.8 1.1 1 0 0 1 1 1 0 Intermediate filament protein DUF4201 PF13870.1 KUM61567.1 - 0.11 11.8 10.9 0.19 11.1 7.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) CENP-H PF05837.7 KUM61567.1 - 0.12 12.5 12.1 0.5 10.5 8.0 1.9 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Hom_end_hint PF05203.11 KUM61567.1 - 0.13 11.9 2.3 0.14 11.8 1.6 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint Prefoldin_2 PF01920.15 KUM61567.1 - 0.15 11.8 11.4 0.29 10.9 7.9 1.4 1 1 0 1 1 1 0 Prefoldin subunit BLOC1_2 PF10046.4 KUM61567.1 - 0.18 11.9 5.9 0.04 14.0 1.0 1.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MRFAP1 PF15155.1 KUM61567.1 - 0.19 12.0 5.5 0.24 11.7 3.8 1.1 1 0 0 1 1 1 0 MORF4 family-associated protein1 HAUS6_N PF14661.1 KUM61567.1 - 0.34 10.2 4.6 0.32 10.3 2.7 1.3 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF2203 PF09969.4 KUM61567.1 - 0.36 11.0 2.6 0.44 10.7 1.8 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF3523 PF12037.3 KUM61567.1 - 0.43 9.5 9.6 0.49 9.3 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) Zwint PF15556.1 KUM61567.1 - 0.56 9.4 9.8 0.66 9.1 6.8 1.1 1 0 0 1 1 1 0 ZW10 interactor GLE1 PF07817.8 KUM61567.1 - 0.65 8.8 5.1 5.4 5.8 0.7 2.0 1 1 1 2 2 2 0 GLE1-like protein Phage_GP20 PF06810.6 KUM61567.1 - 0.7 9.3 11.5 0.26 10.7 2.6 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 Spc7 PF08317.6 KUM61567.1 - 1.5 7.3 10.7 2.1 6.9 7.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Uds1 PF15456.1 KUM61567.1 - 1.9 8.4 11.3 6.6 6.7 7.1 1.9 1 1 1 2 2 2 0 Up-regulated During Septation IncA PF04156.9 KUM61567.1 - 2.4 7.7 14.0 3 7.4 9.7 1.1 1 0 0 1 1 1 0 IncA protein DUF1090 PF06476.7 KUM61567.1 - 2.4 7.8 12.0 2.7 7.6 2.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1090) APG6 PF04111.7 KUM61567.1 - 2.7 6.9 10.7 3.1 6.7 7.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 KUM61567.1 - 3.2 5.5 7.1 3.6 5.3 4.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 KUM61567.1 - 4.3 6.9 10.3 7.1 6.2 7.1 1.4 1 1 0 1 1 1 0 Mnd1 family Seryl_tRNA_N PF02403.17 KUM61567.1 - 4.4 7.3 10.8 6.2 6.8 7.2 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 KUM61567.1 - 4.7 6.7 13.7 1.6 8.2 0.2 2.6 1 1 1 2 2 2 0 Septum formation initiator Atg14 PF10186.4 KUM61567.1 - 5.1 5.9 10.7 7.1 5.4 7.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF724 PF05266.9 KUM61567.1 - 6.7 6.2 13.6 5.6 6.5 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4407 PF14362.1 KUM61567.1 - 7.6 5.3 7.3 35 3.2 5.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Med9 PF07544.8 KUM61567.1 - 9.1 6.0 9.9 1.5 8.5 0.9 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 MutS_V PF00488.16 KUM61569.1 - 6.1e-95 317.1 0.0 9.7e-95 316.4 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KUM61569.1 - 1.8e-38 132.4 0.4 4e-38 131.2 0.3 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 KUM61569.1 - 1.5e-17 63.5 1.0 6.4e-17 61.5 0.7 2.2 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 KUM61569.1 - 1.8e-17 63.6 0.1 6.1e-17 61.9 0.0 2.0 2 0 0 2 2 2 1 MutS domain II MutS_I PF01624.15 KUM61569.1 - 9.6e-15 54.6 0.0 5.3e-14 52.2 0.0 2.2 2 0 0 2 2 2 1 MutS domain I UPF0203 PF05254.7 KUM61570.1 - 1.8e-28 98.1 1.4 2.1e-28 97.9 1.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.8 KUM61570.1 - 0.0018 18.2 0.5 0.0039 17.1 0.3 1.5 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 KUM61570.1 - 0.0035 17.0 1.6 0.067 12.9 1.1 2.1 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3826 PF12875.2 KUM61570.1 - 0.066 12.9 0.1 0.084 12.5 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3826) UCR_hinge PF02320.11 KUM61570.1 - 0.086 12.7 0.4 6.5 6.7 0.0 2.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Gpi1 PF05024.10 KUM61571.1 - 3.8e-62 209.3 8.4 3.8e-62 209.3 5.8 1.6 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Dor1 PF04124.7 KUM61572.1 - 1e-56 191.8 3.3 5e-46 156.7 2.0 2.4 2 0 0 2 2 2 2 Dor1-like family Vps51 PF08700.6 KUM61572.1 - 0.00011 21.9 0.4 0.00033 20.4 0.3 1.9 1 0 0 1 1 1 1 Vps51/Vps67 ApoLp-III PF07464.6 KUM61572.1 - 0.046 13.7 0.4 0.27 11.2 0.1 2.1 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Acetyltransf_3 PF13302.1 KUM61573.1 - 3.2e-08 33.8 0.0 7.1e-08 32.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KUM61573.1 - 0.043 13.8 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF4577 PF15145.1 KUM61574.1 - 0.013 15.3 0.1 0.016 15.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) TadE PF07811.7 KUM61574.1 - 0.061 13.2 1.2 0.098 12.5 0.8 1.2 1 0 0 1 1 1 0 TadE-like protein DUF4330 PF14221.1 KUM61574.1 - 0.08 12.8 0.1 0.099 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) DC_STAMP PF07782.8 KUM61574.1 - 0.12 11.9 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 DC-STAMP-like protein Phosphoesterase PF04185.9 KUM61575.1 - 4.4e-57 194.0 2.9 4.3e-56 190.7 2.0 2.0 1 1 0 1 1 1 1 Phosphoesterase family His_Phos_1 PF00300.17 KUM61578.1 - 6.1e-33 114.1 0.8 3.5e-32 111.6 0.0 2.3 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) VIT1 PF01988.14 KUM61579.1 - 4e-59 199.6 2.3 4.9e-59 199.3 1.6 1.1 1 0 0 1 1 1 1 VIT family 7TMR-DISM_7TM PF07695.6 KUM61579.1 - 0.006 16.2 2.5 0.0092 15.6 1.7 1.2 1 0 0 1 1 1 1 7TM diverse intracellular signalling Abhydrolase_9_N PF15420.1 KUM61579.1 - 0.055 13.2 0.6 0.086 12.5 0.4 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus FIST PF08495.5 KUM61579.1 - 0.13 11.3 0.7 0.21 10.7 0.0 1.6 2 0 0 2 2 2 0 FIST N domain TPIP1 PF15338.1 KUM61581.1 - 0.056 13.3 0.0 0.059 13.2 0.0 1.1 1 0 0 1 1 1 0 p53-regulated apoptosis-inducing protein 1 Fungal_trans PF04082.13 KUM61582.1 - 3.8e-20 71.8 0.0 5.8e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain BRI3BP PF14965.1 KUM61583.1 - 0.006 15.9 8.2 0.46 9.8 0.0 3.9 4 0 0 4 4 4 3 Negative regulator of p53/TP53 Fungal_trans PF04082.13 KUM61584.1 - 1.9e-23 82.6 0.1 3.1e-23 81.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 KUM61585.1 - 6.4e-80 268.9 21.0 7.4e-80 268.7 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM61585.1 - 6e-17 61.3 25.8 7.9e-14 51.1 13.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1113 PF06541.6 KUM61585.1 - 0.059 13.1 13.8 0.022 14.5 2.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1113) His_Phos_2 PF00328.17 KUM61586.1 - 4.5e-41 141.3 0.0 5.3e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) GCFC PF07842.7 KUM61587.1 - 2e-82 276.6 7.4 3.3e-82 275.9 5.1 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 KUM61587.1 - 1e-17 63.6 0.9 2.2e-17 62.5 0.6 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KUM61587.1 - 7.9e-10 38.4 0.6 2.6e-09 36.8 0.4 1.9 1 0 0 1 1 1 1 DExH-box splicing factor binding site DHC_N1 PF08385.7 KUM61587.1 - 0.022 13.1 1.0 0.032 12.6 0.7 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 Sod_Fe_C PF02777.13 KUM61588.1 - 6.7e-37 125.5 0.8 1e-36 124.9 0.1 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KUM61588.1 - 6.5e-30 103.2 2.0 1.2e-29 102.3 1.4 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF3039 PF11238.3 KUM61589.1 - 0.04 13.3 0.1 0.86 9.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) TF_Zn_Ribbon PF08271.7 KUM61589.1 - 0.1 11.9 0.6 13 5.1 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding DUF2798 PF11391.3 KUM61590.1 - 0.37 10.5 1.9 0.7 9.6 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) zf-H2C2_2 PF13465.1 KUM61590.1 - 3.2 8.2 5.2 31 5.0 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double domain PM0188 PF11477.3 KUM61591.1 - 0.026 13.3 0.8 0.043 12.6 0.6 1.2 1 0 0 1 1 1 0 Sialyltransferase PMO188 Microtub_assoc PF07989.6 KUM61591.1 - 4.9 7.0 9.5 4.3 7.2 5.0 2.1 1 1 1 2 2 2 0 Microtubule associated IZUMO PF15005.1 KUM61591.1 - 6 6.8 5.9 12 5.9 4.1 1.4 1 0 0 1 1 1 0 Izumo sperm-egg fusion Sld5 PF05916.6 KUM61592.1 - 8.6e-17 61.3 0.0 1.1e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein DUF4066 PF13278.1 KUM61593.1 - 1.2e-25 89.7 0.0 1.4e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KUM61593.1 - 1e-11 44.4 0.0 1.4e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 KUM61593.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.4 1 1 0 1 1 1 0 Glutamine amidotransferase class-I Transket_pyr PF02779.19 KUM61596.1 - 1.3e-65 220.2 0.0 2.2e-65 219.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KUM61596.1 - 1.9e-56 190.9 0.0 2.6e-56 190.5 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Sugar_tr PF00083.19 KUM61597.1 - 1e-81 274.8 22.1 1.3e-81 274.5 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM61597.1 - 1.3e-25 89.8 52.9 7e-24 84.1 18.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 KUM61597.1 - 0.00037 18.7 3.9 0.0064 14.6 0.2 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector Cation_efflux PF01545.16 KUM61598.1 - 2e-41 141.9 1.7 2.3e-41 141.7 1.2 1.0 1 0 0 1 1 1 1 Cation efflux family DUF1700 PF08006.6 KUM61598.1 - 0.082 12.2 0.1 0.082 12.2 0.1 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1700) DUF3848 PF12959.2 KUM61598.1 - 0.11 12.4 0.1 0.3 11.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) VIT1 PF01988.14 KUM61599.1 - 8.8e-59 198.5 6.2 1e-58 198.3 4.3 1.1 1 0 0 1 1 1 1 VIT family DUF1700 PF08006.6 KUM61599.1 - 1 8.6 3.4 1.6 7.9 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF4202 PF13875.1 KUM61600.1 - 1e-78 263.2 0.1 1.2e-78 263.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) PAM2 PF07145.10 KUM61600.1 - 0.18 11.3 0.3 0.33 10.5 0.2 1.4 1 0 0 1 1 1 0 Ataxin-2 C-terminal region MFS_1 PF07690.11 KUM61601.1 - 1.3e-25 89.9 67.8 1.6e-21 76.4 29.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Condensation PF00668.15 KUM61602.1 - 1.2e-14 53.8 0.0 1.8e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Condensation domain p450 PF00067.17 KUM61603.1 - 2e-49 168.4 0.0 2.5e-49 168.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABM PF03992.11 KUM61604.1 - 2.8e-09 36.8 0.0 3.6e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase NIPSNAP PF07978.8 KUM61604.1 - 0.0076 16.2 0.0 0.0097 15.8 0.0 1.1 1 0 0 1 1 1 1 NIPSNAP Hemocyanin_M PF00372.14 KUM61604.1 - 0.034 13.4 0.4 0.043 13.1 0.3 1.1 1 0 0 1 1 1 0 Hemocyanin, copper containing domain SLS PF14611.1 KUM61604.1 - 0.092 12.1 0.1 0.1 12.0 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Rox3 PF08633.5 KUM61606.1 - 3e-51 174.4 0.2 3e-51 174.4 0.2 2.1 2 1 0 2 2 2 1 Rox3 mediator complex subunit DUF1751 PF08551.5 KUM61607.1 - 0.037 14.3 0.3 0.07 13.4 0.1 1.5 1 1 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) ING PF12998.2 KUM61608.1 - 1.2e-11 44.7 0.3 3.5e-11 43.3 0.0 1.9 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KUM61608.1 - 2.1e-09 36.9 7.8 3.4e-09 36.2 5.4 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 KUM61608.1 - 0.082 13.0 0.5 0.18 12.0 0.3 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain TFIIH_BTF_p62_N PF08567.6 KUM61609.1 - 1.3e-24 85.6 0.0 2.9e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.12 KUM61609.1 - 1.5e-23 82.3 7.5 2.4e-13 49.5 0.5 2.8 3 0 0 3 3 3 2 BSD domain Myb_DNA-bind_6 PF13921.1 KUM61610.1 - 0.00022 21.2 0.1 0.0004 20.4 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KUM61610.1 - 0.0051 16.8 0.9 0.012 15.6 0.6 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain ORC6 PF05460.8 KUM61610.1 - 0.12 11.4 7.6 0.17 10.9 5.2 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Adap_comp_sub PF00928.16 KUM61611.1 - 3.7e-85 285.2 0.0 4.5e-85 284.9 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KUM61611.1 - 2.1e-05 24.2 0.0 3.9e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 KUM61611.1 - 0.006 15.7 0.1 0.0092 15.1 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain SSB PF00436.20 KUM61612.1 - 3.3e-18 65.4 0.0 4e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family STE3 PF02076.10 KUM61613.1 - 2.3e-101 338.6 17.8 2.8e-101 338.3 12.3 1.1 1 0 0 1 1 1 1 Pheromone A receptor Erf4 PF10256.4 KUM61614.1 - 4.7e-33 113.5 0.0 6e-33 113.2 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF4538 PF15061.1 KUM61614.1 - 0.14 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) DUF4203 PF13886.1 KUM61615.1 - 3.8e-42 144.1 23.4 5.9e-42 143.5 16.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Mucin PF01456.12 KUM61615.1 - 0.0038 17.0 31.3 0.0038 17.0 21.7 4.4 5 1 0 5 5 5 2 Mucin-like glycoprotein Pkinase PF00069.20 KUM61616.1 - 6.3e-22 77.9 0.0 2e-21 76.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM61616.1 - 5.3e-08 32.2 0.0 0.024 13.7 0.0 3.5 4 0 0 4 4 4 2 Protein tyrosine kinase CN_hydrolase PF00795.17 KUM61617.1 - 2e-12 46.8 0.0 8.2e-12 44.8 0.0 1.9 1 1 1 2 2 2 1 Carbon-nitrogen hydrolase DUF3114 PF11311.3 KUM61617.1 - 0.047 13.0 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3114) HLH PF00010.21 KUM61618.1 - 1.3e-13 50.4 2.7 2.6e-13 49.4 1.8 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Inhibitor_I9 PF05922.11 KUM61619.1 - 2.8e-13 50.2 0.1 3.1e-13 50.0 0.1 1.0 1 0 0 1 1 1 1 Peptidase inhibitor I9 DPBB_1 PF03330.13 KUM61620.1 - 1.2e-09 38.0 0.1 5.8e-09 35.8 0.0 2.3 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Pollen_allerg_1 PF01357.16 KUM61620.1 - 0.0025 17.5 0.3 0.006 16.3 0.2 1.7 1 0 0 1 1 1 1 Pollen allergen Barwin PF00967.12 KUM61620.1 - 0.0031 17.1 0.1 0.0076 15.9 0.1 1.6 1 0 0 1 1 1 1 Barwin family Cerato-platanin PF07249.7 KUM61620.1 - 0.013 15.5 0.4 0.037 14.0 0.3 1.8 1 0 0 1 1 1 0 Cerato-platanin Mo-co_dimer PF03404.11 KUM61620.1 - 0.061 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain HypA PF01155.14 KUM61620.1 - 0.07 12.8 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Macoilin PF09726.4 KUM61620.1 - 2.2 6.4 8.1 2.7 6.1 5.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Sec8_exocyst PF04048.9 KUM61621.1 - 3.4e-47 159.6 1.1 7.3e-47 158.5 0.8 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 KUM61621.1 - 1.9e-09 36.8 0.4 3.6e-09 35.9 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Zw10 PF06248.8 KUM61621.1 - 0.00017 19.9 0.6 0.00031 19.0 0.4 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Dor1 PF04124.7 KUM61621.1 - 0.024 13.0 2.0 0.043 12.2 1.4 1.3 1 0 0 1 1 1 0 Dor1-like family Sec5 PF15469.1 KUM61621.1 - 0.041 13.6 0.5 0.079 12.6 0.3 1.4 1 0 0 1 1 1 0 Exocyst complex component Sec5 Peptidase_M24 PF00557.19 KUM61622.1 - 3e-39 134.7 0.0 4.5e-39 134.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KUM61622.1 - 2.9e-14 53.6 0.0 1.3e-12 48.3 0.0 2.8 2 1 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Metallophos PF00149.23 KUM61624.1 - 1.2e-11 44.3 1.3 2.7e-11 43.2 0.9 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KUM61624.1 - 6.5e-07 29.3 0.0 1.2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ank_2 PF12796.2 KUM61625.1 - 2.1e-28 98.5 0.0 8.2e-19 67.7 0.0 3.3 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 KUM61625.1 - 2.2e-17 61.8 2.0 0.01 15.5 0.0 6.5 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 KUM61625.1 - 1e-16 60.8 0.1 0.0082 16.6 0.0 7.1 6 2 0 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM61625.1 - 1.1e-12 46.8 3.5 0.052 13.8 0.0 7.0 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.1 KUM61625.1 - 1.1e-11 44.5 1.0 0.00058 20.0 0.0 5.8 4 2 2 6 6 6 3 Ankyrin repeats (many copies) ABC_membrane PF00664.18 KUM61626.1 - 1.5e-72 244.2 28.5 4.6e-38 131.2 6.1 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KUM61626.1 - 4.3e-52 176.0 0.0 5e-30 104.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KUM61626.1 - 1.3e-10 40.8 1.3 0.0043 16.3 0.0 4.0 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KUM61626.1 - 2.5e-07 30.8 1.2 0.0039 17.2 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 KUM61626.1 - 1.4e-06 28.4 0.5 0.39 10.6 0.0 4.8 5 0 0 5 5 5 1 AAA domain MMR_HSR1 PF01926.18 KUM61626.1 - 9e-06 25.6 0.1 0.14 12.0 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 KUM61626.1 - 1.1e-05 24.9 0.1 0.029 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KUM61626.1 - 4.2e-05 22.9 0.4 0.15 11.5 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KUM61626.1 - 0.00018 20.7 0.7 0.024 13.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 KUM61626.1 - 0.00065 20.0 0.1 0.071 13.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KUM61626.1 - 0.0024 18.3 2.7 1.9 8.9 0.0 3.3 3 0 0 3 3 3 2 Miro-like protein Dynamin_N PF00350.18 KUM61626.1 - 0.0043 16.9 0.8 0.4 10.4 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_30 PF13604.1 KUM61626.1 - 0.0053 16.3 1.7 0.79 9.2 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KUM61626.1 - 0.023 14.8 1.7 1.3 9.1 0.0 3.3 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.12 KUM61626.1 - 0.054 13.3 5.0 1.7 8.4 0.1 2.8 3 0 0 3 3 2 0 Domain of unknown function DUF87 AAA_17 PF13207.1 KUM61626.1 - 0.057 14.2 0.0 8 7.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KUM61626.1 - 0.058 12.8 0.1 4.4 6.7 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 KUM61626.1 - 0.068 12.2 0.1 6.1 5.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin ATP-synt_ab PF00006.20 KUM61626.1 - 0.08 12.4 0.0 0.26 10.7 0.0 2.1 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.9 KUM61626.1 - 0.11 12.1 1.1 7.7 6.2 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KUM61626.1 - 0.13 11.6 3.3 3.4 7.0 0.0 3.2 2 1 0 3 3 3 0 AAA-like domain NACHT PF05729.7 KUM61626.1 - 0.53 9.9 4.5 0.27 10.8 0.1 2.6 3 0 0 3 3 3 0 NACHT domain Ank_5 PF13857.1 KUM61627.1 - 9.1e-06 25.7 0.0 2.2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 KUM61627.1 - 0.00041 20.0 0.4 0.0011 18.6 0.3 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 KUM61627.1 - 0.018 15.3 0.0 0.048 14.0 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KUM61627.1 - 0.1 13.1 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) zf-C2H2_2 PF12756.2 KUM61627.1 - 0.1 12.6 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) SAC3_GANP PF03399.11 KUM61630.1 - 3.9e-54 183.3 1.1 5.7e-54 182.7 0.8 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KUM61630.1 - 0.0002 21.1 0.1 0.00057 19.6 0.0 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 DUF2841 PF11001.3 KUM61632.1 - 2.4e-46 156.6 0.0 5.1e-46 155.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Acyl-CoA_dh_M PF02770.14 KUM61633.1 - 2.3e-06 27.0 0.0 4.3e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DIOX_N PF14226.1 KUM61634.1 - 6.7e-18 65.3 0.0 1.8e-17 63.9 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KUM61634.1 - 2.5e-13 50.1 0.0 4.4e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 KUM61635.1 - 1.1e-30 106.5 17.7 1.1e-30 106.5 12.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KUM61635.1 - 7.8e-08 31.1 1.4 9.9e-07 27.4 0.1 2.1 1 1 0 2 2 2 2 MFS/sugar transport protein TPR_11 PF13414.1 KUM61636.1 - 7.6e-11 41.4 9.9 4.8e-08 32.5 0.1 4.4 4 1 1 5 5 5 2 TPR repeat TPR_12 PF13424.1 KUM61636.1 - 2.9e-07 30.3 11.0 0.068 13.1 0.0 5.4 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 KUM61636.1 - 3.4e-07 29.5 9.0 2.9e-06 26.6 0.1 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 KUM61636.1 - 4.2e-06 26.1 8.0 0.0065 16.1 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 KUM61636.1 - 9.5e-06 25.1 19.0 6.7e-05 22.5 0.0 6.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 KUM61636.1 - 0.0011 19.5 11.6 0.48 11.1 1.6 5.9 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 KUM61636.1 - 0.0088 15.7 3.0 0.49 10.2 0.0 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KUM61636.1 - 0.21 11.9 6.6 1.6 9.1 0.2 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 KUM61636.1 - 3.7 8.4 14.9 18 6.3 0.0 6.4 8 0 0 8 8 8 0 Tetratricopeptide repeat GMC_oxred_N PF00732.14 KUM61638.1 - 1.6e-30 106.2 0.0 1.1e-18 67.4 0.0 3.1 2 1 0 3 3 3 3 GMC oxidoreductase GMC_oxred_C PF05199.8 KUM61638.1 - 3e-29 102.1 0.0 5.2e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KUM61638.1 - 0.00037 20.4 0.0 0.00092 19.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KUM61638.1 - 0.002 17.0 1.1 0.012 14.5 0.8 1.9 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KUM61638.1 - 0.005 15.7 2.5 0.043 12.7 1.3 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KUM61638.1 - 0.0082 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KUM61638.1 - 0.073 13.1 0.1 2.8 7.9 0.0 2.8 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KUM61638.1 - 0.076 11.9 0.6 0.13 11.1 0.4 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HHH PF00633.18 KUM61638.1 - 0.15 11.8 3.2 5.7 6.8 0.0 3.0 3 0 0 3 3 3 0 Helix-hairpin-helix motif ApbA PF02558.11 KUM61638.1 - 0.18 11.2 0.5 0.35 10.2 0.3 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Peroxidase_2 PF01328.12 KUM61639.1 - 1.5e-10 40.2 3.4 5.3e-10 38.4 0.3 2.5 2 1 0 2 2 2 1 Peroxidase, family 2 Beta-lactamase PF00144.19 KUM61640.1 - 6.5e-31 107.5 0.0 1.1e-30 106.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase Glyco_hydro_98C PF08307.6 KUM61640.1 - 0.06 12.6 0.0 0.094 11.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 C-terminal domain Zn_clus PF00172.13 KUM61641.1 - 3.3e-06 26.9 11.0 1.1e-05 25.1 7.6 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rhodanese PF00581.15 KUM61642.1 - 8.3e-25 87.3 0.0 1.2e-06 28.8 0.0 4.5 4 0 0 4 4 4 4 Rhodanese-like domain IMPDH PF00478.20 KUM61643.1 - 2.9e-130 434.2 2.7 3.4e-130 434.0 1.8 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 KUM61643.1 - 4.6e-18 64.7 0.0 1.8e-08 34.0 0.0 2.6 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 KUM61643.1 - 4e-10 39.3 7.9 0.0021 17.2 1.1 3.4 3 1 0 3 3 3 3 Nitronate monooxygenase FMN_dh PF01070.13 KUM61643.1 - 4.6e-07 28.9 1.7 8.4e-07 28.1 1.2 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 KUM61643.1 - 0.00017 20.9 3.1 0.00099 18.4 2.1 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.12 KUM61643.1 - 0.0013 17.6 1.2 0.032 13.0 0.2 2.2 1 1 0 2 2 2 1 Dihydrouridine synthase (Dus) Aldolase PF01081.14 KUM61643.1 - 0.025 13.7 2.3 0.028 13.5 0.3 1.9 2 0 0 2 2 2 0 KDPG and KHG aldolase ThiG PF05690.9 KUM61643.1 - 0.036 13.1 3.2 0.055 12.5 0.3 2.2 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG FAD_binding_3 PF01494.14 KUM61644.1 - 3.9e-19 68.9 0.2 4.5e-19 68.7 0.2 1.0 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 KUM61644.1 - 2.4e-08 33.5 0.6 0.0014 17.8 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 KUM61644.1 - 1.3e-07 30.8 4.8 6.7e-05 21.9 1.1 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KUM61644.1 - 1.7e-07 30.4 1.2 0.00041 19.3 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 KUM61644.1 - 3.2e-06 27.0 0.5 2.4e-05 24.2 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KUM61644.1 - 5.2e-06 26.6 0.3 1.7e-05 25.0 0.2 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KUM61644.1 - 7.8e-06 26.2 0.4 0.0012 19.2 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KUM61644.1 - 4.8e-05 22.3 0.2 7.8e-05 21.7 0.1 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 KUM61644.1 - 9.8e-05 20.9 0.4 0.0029 16.1 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KUM61644.1 - 0.00015 20.7 2.0 0.00022 20.2 0.6 1.7 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KUM61644.1 - 0.00015 20.9 0.1 0.0003 19.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KUM61644.1 - 0.00022 21.1 0.1 0.00027 20.8 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KUM61644.1 - 0.00037 19.2 0.6 0.00076 18.2 0.1 1.7 1 1 1 2 2 2 1 Tryptophan halogenase NAD_binding_7 PF13241.1 KUM61644.1 - 0.00096 19.3 0.0 0.0034 17.6 0.0 2.0 1 1 0 1 1 1 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 KUM61644.1 - 0.0012 18.4 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 KUM61644.1 - 0.0017 17.5 0.6 0.0047 16.0 0.4 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase CPSase_L_chain PF00289.17 KUM61644.1 - 0.035 14.2 0.0 0.098 12.7 0.0 1.9 2 1 1 3 3 3 0 Carbamoyl-phosphate synthase L chain, N-terminal domain TrkA_N PF02254.13 KUM61644.1 - 0.037 14.0 0.1 0.082 12.9 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.1 KUM61644.1 - 0.052 13.3 0.4 6.4 6.5 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 KUM61644.1 - 0.061 12.6 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain YgaB PF14182.1 KUM61644.1 - 0.073 13.3 0.1 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 YgaB-like protein AvrPto PF11592.3 KUM61644.1 - 0.089 12.5 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Central core of the bacterial effector protein AvrPto Shikimate_DH PF01488.15 KUM61644.1 - 0.096 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 KUM61644.1 - 0.096 12.3 0.2 0.12 11.9 0.2 1.4 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.11 KUM61646.1 - 4.1e-28 98.1 22.4 4.1e-28 98.1 15.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM61646.1 - 0.002 16.3 0.6 0.0035 15.5 0.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KUM61647.1 - 3.3e-94 316.0 23.2 3.9e-94 315.7 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM61647.1 - 6.1e-30 104.1 42.4 3e-25 88.6 15.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2910 PF11139.3 KUM61647.1 - 0.048 12.7 7.9 0.33 10.0 0.0 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF2910) Sugar_tr PF00083.19 KUM61649.1 - 9e-84 281.6 28.5 1e-83 281.4 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM61649.1 - 2e-20 72.7 27.9 2e-20 72.7 19.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Alpha-amylase PF00128.19 KUM61650.1 - 1.4e-99 333.4 1.2 9.7e-99 330.7 0.2 2.0 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 KUM61650.1 - 0.021 14.9 0.0 0.056 13.5 0.0 1.7 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain hDGE_amylase PF14701.1 KUM61650.1 - 0.031 13.1 0.0 0.06 12.2 0.0 1.4 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Cyc-maltodext_C PF10438.4 KUM61650.1 - 0.092 12.8 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Cyclo-malto-dextrinase C-terminal domain Fungal_trans PF04082.13 KUM61651.1 - 7.5e-08 31.5 4.7 7.8e-08 31.5 0.6 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM61651.1 - 1.3e-07 31.4 10.1 2.1e-07 30.6 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hep_59 PF07052.6 KUM61652.1 - 9.2e-19 67.7 0.1 9.2e-19 67.7 0.1 3.1 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Actin PF00022.14 KUM61653.1 - 1.7e-142 474.5 0.0 1.9e-142 474.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KUM61653.1 - 0.0047 15.5 0.0 1.1 7.7 0.0 2.9 3 0 0 3 3 3 2 MreB/Mbl protein Arf PF00025.16 KUM61654.1 - 1.8e-43 147.8 0.0 2.1e-43 147.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KUM61654.1 - 3.8e-19 68.6 0.0 4.3e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KUM61654.1 - 1.4e-09 38.4 0.0 2.2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 KUM61654.1 - 1.1e-06 28.0 0.0 1.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KUM61654.1 - 3.3e-06 27.0 0.0 5.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KUM61654.1 - 7.8e-06 25.2 0.0 8.8e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 KUM61654.1 - 2.1e-05 24.0 0.0 0.00024 20.6 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 KUM61654.1 - 6.7e-05 21.7 0.3 0.00024 19.8 0.0 1.9 2 1 1 3 3 3 1 G-protein alpha subunit Dynamin_N PF00350.18 KUM61654.1 - 0.0014 18.4 0.1 0.02 14.7 0.1 2.1 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.13 KUM61654.1 - 0.058 12.6 0.2 0.22 10.7 0.0 1.9 2 1 0 2 2 2 0 Ferrous iron transport protein B RNA_pol_Rpb2_6 PF00562.23 KUM61655.1 - 9.2e-118 393.3 0.3 1.2e-117 392.9 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KUM61655.1 - 9.5e-32 109.5 0.0 1.4e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpa2_4 PF06883.7 KUM61655.1 - 1e-25 89.4 0.1 2.5e-25 88.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.9 KUM61655.1 - 1.1e-24 86.9 0.0 2.2e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 KUM61655.1 - 6.4e-24 83.5 0.0 1.6e-23 82.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.15 KUM61655.1 - 2.4e-14 53.3 0.0 8.6e-14 51.5 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 KUM61655.1 - 0.01 15.7 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 Gly-zipper_OmpA PF13436.1 KUM61655.1 - 0.013 15.1 4.1 0.031 13.9 2.8 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Proteasome PF00227.21 KUM61656.1 - 1.4e-10 40.7 0.1 1.4e-08 34.2 0.1 2.1 1 1 0 1 1 1 1 Proteasome subunit Proteasome PF00227.21 KUM61657.1 - 5.9e-20 71.3 0.0 6.8e-20 71.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Pil1 PF13805.1 KUM61659.1 - 1.7e-98 329.1 3.6 2.3e-98 328.6 2.5 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 DUF2508 PF10704.4 KUM61659.1 - 0.058 13.5 0.6 1.6 8.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) IncA PF04156.9 KUM61659.1 - 0.55 9.8 6.8 0.41 10.2 2.7 1.9 1 1 1 2 2 2 0 IncA protein Seryl_tRNA_N PF02403.17 KUM61659.1 - 1.2 9.2 5.9 0.95 9.5 2.2 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 KUM61659.1 - 5.2 6.0 7.9 1.9 7.4 3.5 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 DivIC PF04977.10 KUM61659.1 - 5.3 6.6 9.7 0.76 9.3 0.5 3.0 1 1 1 2 2 2 0 Septum formation initiator SWI-SNF_Ssr4 PF08549.5 KUM61660.1 - 1.8e-256 852.7 22.8 2.1e-235 783.1 4.0 2.0 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1750) Zn_clus PF00172.13 KUM61661.1 - 1.8e-10 40.5 11.6 3.7e-10 39.5 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KUM61661.1 - 0.00022 20.2 0.8 0.0003 19.7 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain AHH PF14412.1 KUM61661.1 - 0.066 13.2 0.3 0.24 11.4 0.2 2.0 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH RRN7 PF11781.3 KUM61661.1 - 0.43 10.1 5.2 0.92 9.0 3.6 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Reo_sigmaC PF04582.7 KUM61662.1 - 0.27 10.3 10.5 0.48 9.5 6.4 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Adenylate_cycl PF01295.13 KUM61662.1 - 0.6 8.2 2.8 0.98 7.6 1.9 1.2 1 0 0 1 1 1 0 Adenylate cyclase, class-I Abhydrolase_3 PF07859.8 KUM61663.1 - 1.3e-43 149.0 0.0 1.7e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KUM61663.1 - 0.0011 18.6 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KUM61663.1 - 0.0056 16.5 0.0 0.011 15.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KUM61663.1 - 0.059 12.0 0.0 0.11 11.1 0.0 1.4 1 0 0 1 1 1 0 Carboxylesterase family PRCH PF03967.8 KUM61664.1 - 2.4 7.7 7.7 48 3.5 0.1 3.6 1 1 3 4 4 4 0 Photosynthetic reaction centre, H-chain N-terminal region HA2 PF04408.18 KUM61665.1 - 9.8e-19 67.2 0.0 2.3e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KUM61665.1 - 2e-13 49.9 0.6 5.3e-13 48.6 0.2 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KUM61665.1 - 1.2e-09 37.9 0.0 2.6e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KUM61665.1 - 1.2e-06 28.7 0.5 7.6e-06 26.0 0.0 2.7 3 1 1 4 4 4 1 AAA domain DUF3602 PF12223.3 KUM61665.1 - 0.0018 18.6 0.0 0.0081 16.5 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3602) DUF3554 PF12074.3 KUM61667.1 - 5.3e-105 351.5 2.7 1.8e-103 346.5 0.7 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF3554) Ribosomal_L19e PF01280.15 KUM61667.1 - 3.5e-58 195.5 8.8 1e-57 194.0 6.1 1.9 1 0 0 1 1 1 1 Ribosomal protein L19e HEAT PF02985.17 KUM61667.1 - 2.5e-34 114.2 31.1 0.042 13.9 0.0 21.0 23 0 0 23 23 23 7 HEAT repeat HEAT_2 PF13646.1 KUM61667.1 - 7.9e-30 102.9 53.1 2.9e-08 33.8 0.0 14.3 10 2 4 14 14 13 7 HEAT repeats HEAT_EZ PF13513.1 KUM61667.1 - 1.4e-24 85.8 61.1 1.3e-05 25.5 0.0 22.1 19 4 7 26 26 24 8 HEAT-like repeat Cnd1 PF12717.2 KUM61667.1 - 8.7e-12 45.2 1.5 0.012 15.4 0.1 7.6 7 1 1 9 9 8 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 KUM61667.1 - 1.2e-10 41.6 0.0 4.4 7.7 0.0 7.9 6 2 1 7 7 7 3 Vacuolar 14 Fab1-binding region ParcG PF10274.4 KUM61667.1 - 3.4e-09 36.8 2.6 0.036 13.9 0.0 6.3 7 1 0 7 7 6 3 Parkin co-regulated protein CLASP_N PF12348.3 KUM61667.1 - 5.3e-07 29.2 0.1 0.34 10.2 0.0 6.5 5 1 2 7 7 7 1 CLASP N terminal AAA_10 PF12846.2 KUM61667.1 - 0.00092 18.7 2.4 3.7 6.8 0.0 4.5 3 1 1 4 4 4 2 AAA-like domain Vitellogenin_N PF01347.17 KUM61667.1 - 0.012 13.8 0.0 0.027 12.7 0.0 1.5 1 0 0 1 1 1 0 Lipoprotein amino terminal region MMS19_C PF12460.3 KUM61667.1 - 0.29 9.8 13.8 1.9 7.1 0.5 6.0 6 0 0 6 6 6 0 RNAPII transcription regulator C-terminal Kelch_6 PF13964.1 KUM61670.1 - 0.0014 18.7 5.3 0.041 14.0 0.1 4.5 4 1 1 5 5 5 1 Kelch motif Kelch_4 PF13418.1 KUM61670.1 - 0.0021 17.8 4.6 0.088 12.5 0.1 4.7 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_3 PF13415.1 KUM61670.1 - 0.0041 17.2 0.1 0.0041 17.2 0.1 5.1 6 1 1 7 7 7 1 Galactose oxidase, central domain Kelch_1 PF01344.20 KUM61670.1 - 0.0064 16.0 0.1 0.65 9.5 0.0 2.8 2 0 0 2 2 2 1 Kelch motif TMEM154 PF15102.1 KUM61670.1 - 0.091 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family SNF2_N PF00176.18 KUM61672.1 - 4.3e-65 219.4 0.1 7.3e-65 218.7 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 KUM61672.1 - 5e-23 80.5 1.7 1.4e-14 53.4 0.1 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 KUM61672.1 - 2.5e-13 49.6 0.0 8.6e-13 47.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4208 PF13907.1 KUM61672.1 - 8.5e-12 45.1 0.1 3.1e-11 43.3 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) DUF3399 PF11879.3 KUM61673.1 - 0.87 9.8 4.0 1.1 9.5 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3399) ABC_tran PF00005.22 KUM61674.1 - 5.4e-35 120.6 0.0 1.4e-16 61.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 KUM61674.1 - 1.8e-14 52.9 5.4 1.8e-14 52.9 3.7 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 KUM61674.1 - 1.2e-13 51.6 2.9 0.036 14.0 0.5 4.2 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 KUM61674.1 - 3.9e-11 42.6 1.6 0.0015 17.8 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KUM61674.1 - 1.3e-06 27.7 0.1 1.3 7.9 0.0 4.4 4 1 1 5 5 5 2 AAA ATPase domain AAA_17 PF13207.1 KUM61674.1 - 1.7e-06 28.8 0.1 0.099 13.4 0.0 3.0 2 2 0 2 2 2 2 AAA domain AAA PF00004.24 KUM61674.1 - 4.3e-06 26.9 0.1 0.0056 16.8 0.1 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 KUM61674.1 - 3.3e-05 23.1 0.7 0.29 10.2 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KUM61674.1 - 3.6e-05 23.2 0.3 0.061 12.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KUM61674.1 - 4.1e-05 23.7 0.0 0.017 15.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4 PF00037.22 KUM61674.1 - 6.5e-05 22.3 2.5 6.5e-05 22.3 1.7 2.8 3 0 0 3 3 3 1 4Fe-4S binding domain AAA_33 PF13671.1 KUM61674.1 - 6.8e-05 22.7 0.0 0.0057 16.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 KUM61674.1 - 8.1e-05 22.2 0.6 0.00083 18.9 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 KUM61674.1 - 8.7e-05 22.8 0.0 0.33 11.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 KUM61674.1 - 0.00026 20.7 1.6 0.025 14.2 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Fer4_21 PF14697.1 KUM61674.1 - 0.00051 19.8 11.6 0.00089 19.0 8.0 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain RNA_helicase PF00910.17 KUM61674.1 - 0.00066 19.8 0.9 0.22 11.6 0.0 2.9 3 0 0 3 3 2 1 RNA helicase AAA_23 PF13476.1 KUM61674.1 - 0.0008 19.7 0.0 0.055 13.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KUM61674.1 - 0.00089 18.9 2.6 0.046 13.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain VirE PF05272.6 KUM61674.1 - 0.0011 18.5 0.1 1.5 8.2 0.0 2.5 2 0 0 2 2 2 2 Virulence-associated protein E Fer4_6 PF12837.2 KUM61674.1 - 0.0015 18.2 10.9 0.0082 15.9 1.5 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_25 PF13481.1 KUM61674.1 - 0.0016 17.8 0.2 1.1 8.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KUM61674.1 - 0.0023 17.9 0.2 1.3 8.9 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.10 KUM61674.1 - 0.0028 16.4 0.0 0.042 12.5 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Thymidylate_kin PF02223.12 KUM61674.1 - 0.0066 15.8 0.0 1.5 8.1 0.0 2.6 2 0 0 2 2 2 1 Thymidylate kinase SRP54 PF00448.17 KUM61674.1 - 0.008 15.6 3.7 0.11 11.9 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Miro PF08477.8 KUM61674.1 - 0.013 15.9 0.1 0.96 9.9 0.0 2.8 3 0 0 3 3 2 0 Miro-like protein SbcCD_C PF13558.1 KUM61674.1 - 0.014 15.2 0.1 9.4 6.2 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fer4_10 PF13237.1 KUM61674.1 - 0.017 14.9 1.7 0.017 14.9 1.2 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_5 PF07728.9 KUM61674.1 - 0.02 14.6 0.2 1.1 8.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF815 PF05673.8 KUM61674.1 - 0.026 13.4 0.0 1.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Fer4_7 PF12838.2 KUM61674.1 - 0.032 14.6 1.8 0.032 14.6 1.3 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain AAA_30 PF13604.1 KUM61674.1 - 0.036 13.6 0.2 0.87 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Fer4_16 PF13484.1 KUM61674.1 - 0.04 14.6 0.1 0.04 14.6 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain NTPase_1 PF03266.10 KUM61674.1 - 0.058 13.1 1.8 2.4 7.8 0.1 2.5 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.17 KUM61674.1 - 0.065 12.0 0.1 7 5.4 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.1 KUM61674.1 - 0.084 12.7 1.3 6.9 6.5 0.1 3.0 2 2 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KUM61674.1 - 0.086 12.7 0.1 7.2 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KUM61674.1 - 0.09 12.3 2.1 0.58 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 KUM61674.1 - 0.13 11.6 2.4 0.2 11.1 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KaiC PF06745.8 KUM61674.1 - 0.15 11.1 0.1 0.33 10.0 0.0 1.5 1 0 0 1 1 1 0 KaiC Fer4_17 PF13534.1 KUM61674.1 - 0.15 12.4 0.2 0.15 12.4 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain ArgK PF03308.11 KUM61674.1 - 0.15 10.8 0.3 1.4 7.6 0.0 2.1 2 0 0 2 2 2 0 ArgK protein AAA_13 PF13166.1 KUM61674.1 - 0.19 10.1 1.1 0.23 9.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain Fer4_2 PF12797.2 KUM61674.1 - 0.39 10.7 12.7 0.47 10.4 1.9 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.1 KUM61674.1 - 0.5 10.4 9.5 0.28 11.2 1.2 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 KUM61674.1 - 0.64 10.3 13.6 0.048 13.9 1.5 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Aminotran_3 PF00202.16 KUM61676.1 - 4.8e-14 51.9 0.0 6.5e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Prp31_C PF09785.4 KUM61678.1 - 3.3e-43 147.0 0.2 6.9e-43 146.0 0.2 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 KUM61678.1 - 3.1e-36 123.9 0.1 4.8e-36 123.3 0.1 1.3 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KUM61678.1 - 6.6e-15 54.6 0.0 1.2e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 NOSIC (NUC001) domain HAT PF02184.11 KUM61679.1 - 6.2e-20 70.6 74.9 2.8e-15 55.7 2.6 12.6 14 0 0 14 14 14 4 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 KUM61679.1 - 1e-19 69.2 10.7 0.00066 20.0 0.1 10.6 7 2 4 11 11 11 3 Tetratricopeptide repeat TPR_19 PF14559.1 KUM61679.1 - 2.6e-15 56.4 2.2 1.1e-05 25.6 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 KUM61679.1 - 5e-13 49.3 13.8 0.011 16.3 0.0 7.8 8 1 2 10 10 10 4 Tetratricopeptide repeat Suf PF05843.9 KUM61679.1 - 6.8e-11 42.4 20.7 0.0016 18.2 0.1 6.0 2 2 2 6 6 6 3 Suppressor of forked protein (Suf) TPR_17 PF13431.1 KUM61679.1 - 8e-08 31.9 3.8 0.54 10.5 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 KUM61679.1 - 2.1e-07 30.4 5.4 0.52 10.0 0.0 6.6 6 1 0 6 6 6 2 TPR repeat TPR_2 PF07719.12 KUM61679.1 - 3.3e-07 29.6 9.8 0.17 11.9 0.0 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 KUM61679.1 - 6.2e-06 26.0 15.7 7.7 6.5 0.0 7.9 8 1 0 8 8 8 1 Tetratricopeptide repeat NRDE-2 PF08424.5 KUM61679.1 - 1.3e-05 24.2 25.2 0.0074 15.2 5.2 4.9 3 3 1 4 4 4 3 NRDE-2, necessary for RNA interference RAB3GAP2_C PF14656.1 KUM61679.1 - 0.0019 16.4 0.0 0.0027 15.9 0.0 1.2 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit C-terminus U3_assoc_6 PF08640.6 KUM61679.1 - 0.017 14.8 1.4 0.017 14.8 1.0 6.8 6 1 1 7 7 6 0 U3 small nucleolar RNA-associated protein 6 TPR_7 PF13176.1 KUM61679.1 - 0.099 12.4 18.4 5.4 7.0 0.0 6.9 8 1 0 9 9 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 KUM61679.1 - 0.14 11.8 7.4 7.2 6.3 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 KUM61679.1 - 0.83 10.2 17.8 13 6.5 0.0 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat Lactamase_B PF00753.22 KUM61680.1 - 8.6e-08 32.0 0.8 1.6e-07 31.1 0.5 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KUM61680.1 - 7.6e-06 25.5 0.2 1.2e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain zf-C2H2_4 PF13894.1 KUM61683.1 - 2.2e-08 33.8 10.2 1.3e-05 25.1 1.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KUM61683.1 - 9.9e-08 31.8 10.4 6.8e-06 26.1 1.7 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KUM61683.1 - 7.3e-06 26.0 2.3 7.3e-06 26.0 1.6 4.1 4 0 0 4 4 4 1 Zinc-finger double domain zf-met PF12874.2 KUM61683.1 - 0.00067 19.7 0.5 0.00067 19.7 0.3 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type DUF2225 PF09986.4 KUM61683.1 - 0.0013 18.2 0.3 0.0021 17.5 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) zf-Di19 PF05605.7 KUM61683.1 - 0.0035 17.4 6.9 0.0066 16.5 4.3 1.9 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 KUM61683.1 - 0.006 16.6 0.9 0.006 16.6 0.6 2.1 2 0 0 2 2 1 1 Zinc-finger double-stranded RNA-binding DUF1178 PF06676.6 KUM61683.1 - 0.0082 16.3 0.6 0.015 15.5 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1178) PRP21_like_P PF12230.3 KUM61683.1 - 0.063 12.7 0.5 0.095 12.1 0.4 1.3 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf-C2H2_2 PF12756.2 KUM61683.1 - 0.24 11.5 3.4 0.4 10.8 2.3 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 KUM61683.1 - 0.31 10.8 6.4 0.73 9.6 4.4 1.6 1 0 0 1 1 1 0 BED zinc finger UPF0261 PF06792.6 KUM61684.1 - 4.9e-145 483.0 0.6 5.6e-145 482.8 0.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) AdoHcyase PF05221.12 KUM61685.1 - 1.2e-136 453.9 0.1 1.4e-136 453.6 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 KUM61685.1 - 2.5e-81 271.3 2.8 4.2e-81 270.5 2.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KUM61685.1 - 2e-06 27.0 0.1 4.5e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 KUM61685.1 - 0.0018 17.6 0.3 0.0033 16.7 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 KUM61685.1 - 0.0032 17.4 0.1 0.0068 16.3 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 KUM61685.1 - 0.0042 16.7 0.1 0.0075 15.8 0.1 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase RPM2 PF08579.6 KUM61685.1 - 0.028 14.5 0.0 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) F420_oxidored PF03807.12 KUM61685.1 - 0.033 14.6 0.2 0.069 13.5 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Oxidored_nitro PF00148.14 KUM61685.1 - 0.039 12.6 0.1 0.2 10.2 0.0 2.1 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase 3HCDH_N PF02737.13 KUM61685.1 - 0.13 11.8 0.5 0.25 10.9 0.4 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-H2C2_2 PF13465.1 KUM61686.1 - 1e-06 28.6 9.4 1.5e-06 28.1 0.6 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KUM61686.1 - 2.7e-05 24.1 10.1 9.4e-05 22.4 0.3 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KUM61686.1 - 9.8e-05 22.4 0.7 9.8e-05 22.4 0.5 3.3 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KUM61686.1 - 0.0018 18.1 0.1 0.33 10.9 0.0 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KUM61686.1 - 0.04 14.0 5.4 0.14 12.3 0.3 3.0 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KUM61686.1 - 0.17 12.0 1.8 8.1 6.8 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Aldo_ket_red PF00248.16 KUM61688.1 - 3.9e-49 167.0 0.0 4.6e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Hemopexin PF00045.14 KUM61689.1 - 1.8e-14 53.1 4.9 0.0001 21.9 0.1 4.1 4 0 0 4 4 4 3 Hemopexin Ten_N PF06484.7 KUM61690.1 - 0.068 12.2 3.4 0.1 11.7 2.4 1.2 1 0 0 1 1 1 0 Teneurin Intracellular Region PhyH PF05721.8 KUM61691.1 - 3.1e-08 33.9 0.0 1e-07 32.2 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) L27_2 PF09045.5 KUM61692.1 - 0.081 12.4 0.1 0.18 11.3 0.1 1.6 1 0 0 1 1 1 0 L27_2 Glyco_hydro_15 PF00723.16 KUM61696.1 - 9e-43 146.4 0.0 1.4e-42 145.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Glyco_hydro_15 PF00723.16 KUM61697.1 - 0.0003 19.5 0.0 0.0003 19.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Cullin PF00888.17 KUM61698.1 - 1.7e-47 162.2 0.2 2.8e-47 161.5 0.1 1.2 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 KUM61698.1 - 6.8e-22 77.4 0.0 5.9e-21 74.4 0.0 2.3 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 TauD PF02668.11 KUM61699.1 - 9.3e-27 94.3 0.0 1.2e-26 93.9 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sugar_tr PF00083.19 KUM61700.1 - 2.4e-118 395.6 15.9 3.3e-118 395.1 11.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM61700.1 - 3.1e-27 95.2 30.9 6.1e-24 84.3 16.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkr1 PF08636.5 KUM61701.1 - 4.1e-33 113.2 7.6 5.3e-33 112.8 5.3 1.1 1 0 0 1 1 1 1 ER protein Pkr1 FHIPEP PF00771.15 KUM61701.1 - 0.021 13.1 0.1 0.024 12.9 0.0 1.0 1 0 0 1 1 1 0 FHIPEP family Ashwin PF15323.1 KUM61701.1 - 0.04 13.9 1.0 0.05 13.5 0.7 1.1 1 0 0 1 1 1 0 Developmental protein GATase PF00117.23 KUM61702.1 - 0.00068 19.1 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C15 PF01470.12 KUM61704.1 - 2e-13 50.6 0.0 3.9e-05 23.5 0.0 2.8 2 1 0 2 2 2 2 Pyroglutamyl peptidase MOSC_N PF03476.11 KUM61705.1 - 3.9e-21 74.9 0.0 3.7e-20 71.8 0.0 2.1 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 KUM61705.1 - 1.5e-15 56.8 0.0 1.2e-09 37.6 0.0 2.3 2 0 0 2 2 2 2 MOSC domain SWIB PF02201.13 KUM61706.1 - 0.021 14.4 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 SWIB/MDM2 domain p450 PF00067.17 KUM61707.1 - 6.9e-40 136.9 0.0 8.3e-40 136.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cob_adeno_trans PF01923.13 KUM61707.1 - 0.091 12.5 0.7 0.75 9.5 0.0 2.5 2 2 0 2 2 2 0 Cobalamin adenosyltransferase Pkinase PF00069.20 KUM61708.1 - 1.8e-12 46.9 0.0 1.1e-11 44.4 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM61708.1 - 0.002 17.2 0.0 0.01 14.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM61708.1 - 0.11 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like AP_endonuc_2 PF01261.19 KUM61710.1 - 1.4e-24 86.5 0.1 2e-24 86.0 0.1 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Mad3_BUB1_I PF08311.7 KUM61711.1 - 5.8e-44 148.9 0.0 7.9e-44 148.4 0.0 1.2 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 TPT PF03151.11 KUM61713.1 - 6.5e-30 103.8 10.7 6.5e-30 103.8 7.4 2.3 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KUM61713.1 - 5.5e-05 23.2 31.1 0.0013 18.7 7.5 2.9 2 2 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 KUM61713.1 - 0.00079 18.4 21.3 0.00079 18.4 14.8 1.6 2 0 0 2 2 2 1 UAA transporter family Lactonase PF10282.4 KUM61714.1 - 5.1e-84 282.2 0.0 6.1e-84 282.0 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller He_PIG PF05345.7 KUM61714.1 - 0.0061 16.5 0.3 0.016 15.1 0.2 1.8 1 0 0 1 1 1 1 Putative Ig domain CwfJ_C_1 PF04677.10 KUM61715.1 - 3.8e-24 84.6 0.0 7.8e-24 83.6 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 KUM61715.1 - 9.5e-21 74.1 0.2 1.7e-20 73.2 0.1 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DRIM PF07539.7 KUM61716.1 - 2.5e-45 153.3 0.1 1.2e-44 151.1 0.0 2.3 3 0 0 3 3 3 1 Down-regulated in metastasis HEAT PF02985.17 KUM61716.1 - 0.031 14.3 8.2 0.14 12.3 0.0 6.2 7 0 0 7 7 7 0 HEAT repeat BP28CT PF08146.7 KUM61716.1 - 0.035 13.8 4.4 0.068 12.8 0.0 3.8 4 0 0 4 4 4 0 BP28CT (NUC211) domain BLOC1_2 PF10046.4 KUM61716.1 - 0.079 13.1 2.0 0.57 10.3 0.0 3.2 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Rhodanese PF00581.15 KUM61717.1 - 6.5e-13 49.0 0.0 1.3e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Adeno_E3_CR2 PF02439.10 KUM61719.1 - 6.8 6.3 7.3 0.56 9.7 1.3 1.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 zf-DNL PF05180.7 KUM61720.1 - 8.4e-29 99.0 1.3 9.3e-29 98.9 0.2 1.6 2 0 0 2 2 2 1 DNL zinc finger zf-CSL PF05207.8 KUM61720.1 - 1e-05 24.9 0.3 1.9e-05 24.0 0.2 1.4 1 0 0 1 1 1 1 CSL zinc finger TFIIS_C PF01096.13 KUM61720.1 - 0.00077 19.0 3.5 0.041 13.5 0.5 2.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Elf1 PF05129.8 KUM61720.1 - 0.0068 16.0 0.2 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like E7 PF00527.13 KUM61720.1 - 0.018 15.1 0.8 0.018 15.1 0.6 2.2 1 1 1 2 2 2 0 E7 protein, Early protein zf-DNA_Pol PF08996.5 KUM61720.1 - 0.046 13.0 0.3 0.074 12.3 0.2 1.3 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger DUF2039 PF10217.4 KUM61720.1 - 0.076 13.0 0.7 0.13 12.3 0.5 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Zn-ribbon_8 PF09723.5 KUM61720.1 - 0.079 12.9 1.8 0.23 11.4 1.3 1.7 1 1 0 1 1 1 0 Zinc ribbon domain HypA PF01155.14 KUM61720.1 - 0.12 12.0 0.6 0.2 11.3 0.4 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DNA_RNApol_7kD PF03604.8 KUM61720.1 - 0.14 11.6 1.6 3.5 7.1 0.1 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit HECT_2 PF09814.4 KUM61720.1 - 0.22 10.2 2.8 0.34 9.5 2.0 1.3 1 1 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Zn_Tnp_IS1595 PF12760.2 KUM61720.1 - 0.94 9.3 7.2 16 5.3 4.8 2.4 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Cullin PF00888.17 KUM61721.1 - 9.5e-128 427.2 12.6 1.3e-127 426.7 8.7 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KUM61721.1 - 2.2e-27 94.6 2.4 2.6e-27 94.4 0.3 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain DNA_pol_phi PF04931.8 KUM61722.1 - 8.7e-70 235.4 15.0 1.2e-69 234.9 10.4 1.2 1 0 0 1 1 1 1 DNA polymerase phi BUD22 PF09073.5 KUM61722.1 - 1.6 7.6 22.7 3.5 6.5 15.7 1.6 1 0 0 1 1 1 0 BUD22 SLAC1 PF03595.12 KUM61725.1 - 2.4e-67 226.9 28.5 2.7e-67 226.7 19.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Prenyltrans_2 PF13249.1 KUM61726.1 - 7.5e-56 187.3 14.6 2.5e-16 60.0 0.1 5.3 2 1 4 6 6 6 6 Prenyltransferase-like Prenyltrans_1 PF13243.1 KUM61726.1 - 5.3e-32 110.0 3.4 2.5e-14 53.1 0.0 5.9 4 2 1 5 5 5 4 Prenyltransferase-like Prenyltrans PF00432.16 KUM61726.1 - 2.5e-29 100.5 20.0 1.4e-09 37.3 0.1 7.7 8 0 0 8 8 8 4 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.5 KUM61726.1 - 1.1e-07 31.2 4.0 0.85 8.7 0.0 5.5 5 1 1 6 6 6 3 Pectic acid lyase A2M_comp PF07678.9 KUM61726.1 - 4.8e-06 25.9 0.0 0.38 9.9 0.0 4.8 5 0 0 5 5 5 2 A-macroglobulin complement component Transferase PF02458.10 KUM61727.1 - 0.014 13.8 0.0 0.018 13.5 0.0 1.1 1 0 0 1 1 1 0 Transferase family p450 PF00067.17 KUM61729.1 - 6.7e-10 38.0 0.0 1.1e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 KUM61730.1 - 1.4e-84 275.2 15.8 5.1e-14 51.5 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat PD40 PF07676.7 KUM61730.1 - 3.3e-08 32.9 0.7 0.053 13.1 0.0 5.7 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 KUM61730.1 - 6.5e-06 25.3 1.1 20 4.6 0.2 5.4 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Nup160 PF11715.3 KUM61730.1 - 2e-05 22.9 9.3 0.24 9.5 0.0 4.5 2 1 3 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KUM61730.1 - 0.00012 20.9 0.4 0.19 10.4 0.1 3.9 1 1 3 4 4 4 1 Nup133 N terminal like Ribosomal_L21e PF01157.13 KUM61730.1 - 0.00031 20.4 0.0 0.82 9.5 0.0 2.7 3 0 0 3 3 3 2 Ribosomal protein L21e DUF2415 PF10313.4 KUM61730.1 - 0.00065 19.3 1.3 14 5.4 0.0 5.2 5 0 0 5 5 5 0 Uncharacterised protein domain (DUF2415) DUF1258 PF06869.7 KUM61730.1 - 0.0029 16.7 0.0 0.38 9.8 0.0 3.0 1 1 1 3 3 3 1 Protein of unknown function (DUF1258) Stimulus_sens_1 PF13756.1 KUM61730.1 - 0.014 15.7 0.1 39 4.6 0.0 3.9 4 0 0 4 4 4 0 Stimulus-sensing domain DUF1921 PF09081.5 KUM61730.1 - 0.052 13.5 0.8 3 7.8 0.0 4.0 4 1 0 4 4 4 0 Domain of unknown function (DUF1921) Apc4_WD40 PF12894.2 KUM61730.1 - 0.057 12.9 0.0 6.6 6.3 0.0 3.1 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain FtsQ PF03799.10 KUM61730.1 - 0.07 13.3 0.1 73 3.5 0.0 3.9 4 1 1 5 5 5 0 Cell division protein FtsQ PQQ_2 PF13360.1 KUM61730.1 - 0.098 12.0 3.6 0.61 9.4 1.1 2.7 1 1 1 2 2 2 0 PQQ-like domain MFS_1 PF07690.11 KUM61731.1 - 6.6e-32 110.5 26.6 6.6e-32 110.5 18.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Ank_2 PF12796.2 KUM61732.1 - 5.4e-77 254.2 13.0 3.4e-16 59.3 0.1 5.1 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KUM61732.1 - 1.8e-45 150.5 11.5 3.2e-08 32.9 0.2 10.0 10 0 0 10 10 10 8 Ankyrin repeat Ank_3 PF13606.1 KUM61732.1 - 7.7e-37 121.6 2.8 0.0015 18.6 0.0 8.9 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 KUM61732.1 - 2.4e-32 110.6 7.0 9.2e-08 32.4 0.1 6.8 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM61732.1 - 2.8e-28 97.2 11.5 1.6e-10 40.8 0.1 7.5 3 2 5 8 8 8 7 Ankyrin repeats (many copies) F-box-like PF12937.2 KUM61732.1 - 0.012 15.2 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 F-box-like Ank_5 PF13857.1 KUM61733.1 - 7.2e-16 57.8 0.0 6.6e-07 29.3 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KUM61733.1 - 3e-15 56.3 0.0 2.9e-12 46.7 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KUM61733.1 - 1.9e-14 53.6 0.1 1.1e-06 28.9 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KUM61733.1 - 2.7e-12 45.8 0.2 0.00027 20.5 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 KUM61733.1 - 3.9e-10 38.9 0.1 0.012 15.7 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Shikimate_DH PF01488.15 KUM61733.1 - 0.054 13.5 0.0 0.075 13.1 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DASH_Hsk3 PF08227.6 KUM61734.1 - 7.9e-22 77.1 2.1 1.1e-21 76.7 1.4 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like Big_3_3 PF13750.1 KUM61734.1 - 0.036 13.4 0.6 0.045 13.1 0.4 1.1 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) ApbA PF02558.11 KUM61735.1 - 9.3e-25 86.8 0.0 1.4e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KUM61735.1 - 5e-19 68.5 0.0 8.7e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal WH2 PF02205.15 KUM61736.1 - 0.019 14.5 3.5 0.55 9.9 2.4 2.5 1 1 0 1 1 1 0 WH2 motif F-box-like PF12937.2 KUM61737.1 - 5.3e-06 26.0 0.7 1.4e-05 24.7 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KUM61737.1 - 0.0075 15.8 0.8 0.019 14.6 0.1 2.1 2 0 0 2 2 2 1 F-box domain CorA PF01544.13 KUM61738.1 - 2.3e-07 30.1 0.0 3.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein AdoMet_MTase PF07757.8 KUM61739.1 - 1.3e-25 89.6 0.0 2.7e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase His_Phos_1 PF00300.17 KUM61740.1 - 2.8e-29 102.2 0.0 3.4e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF604 PF04646.7 KUM61741.1 - 8.5e-06 25.1 0.0 1.3e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.11 KUM61741.1 - 0.00028 20.2 0.0 0.00058 19.1 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Ser_hydrolase PF06821.8 KUM61741.1 - 0.033 13.7 0.2 0.065 12.8 0.1 1.4 1 0 0 1 1 1 0 Serine hydrolase MFS_1 PF07690.11 KUM61742.1 - 4.2e-41 140.8 23.1 4.2e-41 140.8 16.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM61742.1 - 1.6e-14 53.3 4.5 1.6e-14 53.3 3.1 2.1 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.15 KUM61742.1 - 0.0016 16.6 1.7 0.0026 15.8 0.5 1.8 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Lipase_3 PF01764.20 KUM61743.1 - 2.1e-15 56.5 0.1 6.6e-12 45.2 0.0 2.3 2 0 0 2 2 2 2 Lipase (class 3) Abhydrolase_5 PF12695.2 KUM61743.1 - 0.0041 16.8 0.0 0.0078 15.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KUM61743.1 - 0.0053 16.6 0.1 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family zf-H2C2_2 PF13465.1 KUM61744.1 - 1.4e-05 25.1 10.9 1.8e-05 24.7 0.6 3.6 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.21 KUM61744.1 - 0.0001 22.3 15.5 0.0024 18.0 3.1 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KUM61744.1 - 0.015 15.6 13.4 0.076 13.3 1.6 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 KUM61744.1 - 0.2 11.4 11.5 0.65 9.8 2.1 2.6 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.5 KUM61744.1 - 0.22 11.5 2.2 3.2 7.7 0.2 2.4 2 0 0 2 2 2 0 Zinc ribbon domain SMC_N PF02463.14 KUM61745.1 - 2.3e-22 79.3 0.0 6.8e-22 77.7 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KUM61745.1 - 2.7e-14 53.9 13.9 2.7e-14 53.9 9.6 4.9 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.1 KUM61745.1 - 2.3e-06 27.7 1.1 0.00096 19.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 KUM61745.1 - 0.0003 20.2 0.0 0.00061 19.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 KUM61745.1 - 0.00075 18.0 22.0 0.00075 18.0 15.3 4.7 3 2 2 5 5 5 3 AAA domain ABC_tran PF00005.22 KUM61745.1 - 0.09 13.0 0.0 0.09 13.0 0.0 4.6 3 2 0 3 3 3 0 ABC transporter AAA_25 PF13481.1 KUM61745.1 - 0.12 11.7 0.0 0.12 11.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 KUM61745.1 - 1.3 9.9 0.0 1.3 9.9 0.0 4.1 3 2 0 3 3 3 0 AAA domain BTB PF00651.26 KUM61746.1 - 4.6e-27 94.2 0.0 2.2e-13 50.1 0.2 2.7 2 0 0 2 2 2 2 BTB/POZ domain Ank_2 PF12796.2 KUM61746.1 - 5.1e-10 39.5 0.0 1.2e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KUM61746.1 - 1.4e-07 31.5 0.1 6.3e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 KUM61746.1 - 1.5e-07 30.8 0.2 2.2e-05 24.0 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 KUM61746.1 - 2.9e-07 30.8 0.0 6.7e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM61746.1 - 0.00053 19.9 0.1 0.0082 16.2 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Pkinase PF00069.20 KUM61747.1 - 8.1e-58 195.5 0.3 2e-57 194.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM61747.1 - 1.4e-36 125.8 0.0 5.7e-26 91.1 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KUM61747.1 - 0.018 14.0 0.0 0.037 13.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KUM61747.1 - 0.1 12.2 0.8 0.6 9.7 0.0 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family Wbp11 PF09429.5 KUM61748.1 - 5.9e-23 80.6 13.2 5.9e-23 80.6 9.2 2.3 2 1 0 2 2 2 1 WW domain binding protein 11 Perilipin PF03036.11 KUM61749.1 - 0.0017 17.2 0.4 0.002 17.0 0.2 1.1 1 0 0 1 1 1 1 Perilipin family Baculo_PEP_C PF04513.7 KUM61749.1 - 0.0082 15.9 1.1 0.077 12.8 0.6 2.1 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus PhaP_Bmeg PF09602.5 KUM61749.1 - 0.011 15.5 0.0 0.011 15.5 0.0 1.5 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Syntaxin PF00804.20 KUM61749.1 - 0.012 15.8 7.8 0.054 13.6 0.7 2.5 2 1 1 3 3 2 0 Syntaxin Fzo_mitofusin PF04799.8 KUM61749.1 - 0.016 14.6 0.8 0.03 13.7 0.5 1.5 1 1 0 1 1 1 0 fzo-like conserved region DUF1664 PF07889.7 KUM61749.1 - 0.027 14.2 2.5 0.53 10.0 1.7 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) PLU-1 PF08429.6 KUM61749.1 - 0.038 12.8 0.1 0.056 12.3 0.1 1.2 1 0 0 1 1 1 0 PLU-1-like protein DUF2365 PF10157.4 KUM61749.1 - 0.054 13.3 0.1 0.081 12.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) DHC_N2 PF08393.8 KUM61749.1 - 0.059 11.8 0.1 0.075 11.5 0.1 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 COG5 PF10392.4 KUM61749.1 - 0.065 13.2 2.2 2 8.3 0.1 2.2 1 1 1 2 2 2 0 Golgi transport complex subunit 5 NAP PF00956.13 KUM61749.1 - 0.071 12.2 0.2 0.089 11.9 0.1 1.1 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) Prefoldin_2 PF01920.15 KUM61749.1 - 0.089 12.5 0.5 7 6.4 0.1 2.5 1 1 1 2 2 2 0 Prefoldin subunit HSCB_C PF07743.8 KUM61749.1 - 0.092 13.2 2.3 0.85 10.1 0.2 2.3 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain KKLCAg1 PF15204.1 KUM61749.1 - 0.16 12.0 0.7 0.28 11.2 0.0 1.8 2 0 0 2 2 2 0 Kita-kyushu lung cancer antigen 1 ING PF12998.2 KUM61749.1 - 0.36 11.1 3.8 2 8.7 0.1 2.1 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Vps51 PF08700.6 KUM61749.1 - 0.4 10.5 3.8 15 5.5 2.2 2.8 1 1 1 2 2 2 0 Vps51/Vps67 Matrilin_ccoil PF10393.4 KUM61749.1 - 0.64 9.4 3.4 0.89 8.9 0.2 2.6 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin GreA_GreB_N PF03449.10 KUM61749.1 - 0.78 9.8 4.5 1.7 8.7 0.2 2.8 3 0 0 3 3 3 0 Transcription elongation factor, N-terminal CorA PF01544.13 KUM61749.1 - 0.83 8.6 4.4 1.2 8.1 3.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein THOC7 PF05615.8 KUM61749.1 - 2.8 8.2 6.2 2 8.6 2.1 2.3 2 1 0 2 2 1 0 Tho complex subunit 7 Fib_alpha PF08702.5 KUM61749.1 - 3.6 7.7 7.1 0.57 10.2 2.1 1.7 2 1 0 2 2 1 0 Fibrinogen alpha/beta chain family ORF11CD3 PF10549.4 KUM61749.1 - 9.4 6.0 10.2 1.2 8.8 0.2 3.0 4 0 0 4 4 4 0 ORF11CD3 domain Rpr2 PF04032.11 KUM61750.1 - 6.1e-26 90.1 1.4 9.4e-26 89.5 1.0 1.3 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Nudix_N_2 PF14803.1 KUM61750.1 - 0.13 11.9 1.2 0.87 9.3 0.1 2.5 2 0 0 2 2 2 0 Nudix N-terminal DEAD PF00270.24 KUM61751.1 - 2.1e-35 121.7 0.4 3.5e-35 120.9 0.1 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM61751.1 - 3.3e-24 84.5 0.0 4.4e-23 80.9 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KUM61751.1 - 7.1e-07 29.2 0.1 2.1e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit BNR_2 PF13088.1 KUM61751.1 - 0.014 14.6 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 BNR repeat-like domain MFS_1 PF07690.11 KUM61753.1 - 4.3e-13 48.7 25.7 7.2e-13 47.9 16.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM61753.1 - 3.1e-07 29.3 8.6 5.6e-07 28.5 5.5 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter UNC-93 PF05978.11 KUM61753.1 - 3.4e-06 26.6 1.5 3.4e-06 26.6 1.0 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 ATP-grasp_4 PF13535.1 KUM61754.1 - 0.00088 19.0 0.0 0.4 10.3 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Phage_head_fibr PF11133.3 KUM61754.1 - 0.14 11.2 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Head fiber protein Fungal_trans PF04082.13 KUM61755.1 - 2.3e-21 75.8 0.8 7.2e-21 74.2 0.6 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF3294 PF07957.6 KUM61755.1 - 0.03 13.8 0.1 0.052 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) Ribonuc_L-PSP PF01042.16 KUM61756.1 - 2.5e-12 46.5 0.0 3.1e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Gly_transf_sug PF04488.10 KUM61757.1 - 3.4e-12 46.6 0.0 8.1e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KUM61757.1 - 0.00033 19.2 0.1 0.038 12.4 0.0 2.2 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain Amidinotransf PF02274.12 KUM61757.1 - 0.049 12.7 0.0 0.058 12.4 0.0 1.2 1 0 0 1 1 1 0 Amidinotransferase Transketolase_N PF00456.16 KUM61758.1 - 7.1e-16 57.9 0.7 1.2e-14 53.9 0.5 2.1 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.15 KUM61758.1 - 7.1e-11 42.1 0.0 1.7e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.19 KUM61758.1 - 7.2e-06 25.6 1.0 3.1e-05 23.5 0.2 2.1 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.16 KUM61758.1 - 0.00053 19.5 0.5 0.0031 17.0 0.3 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 KUM61758.1 - 0.013 14.2 0.0 0.019 13.6 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component Glyco_hydro_30 PF02055.11 KUM61759.1 - 1.6e-46 158.5 2.0 2.2e-46 158.1 1.4 1.1 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 MFS_1 PF07690.11 KUM61760.1 - 2.7e-33 115.1 28.6 7e-33 113.7 18.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3139 PF11337.3 KUM61760.1 - 0.054 13.7 0.2 0.46 10.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3139) Pyr_redox PF00070.22 KUM61761.1 - 8.8e-10 38.8 0.5 1.9e-09 37.7 0.3 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MFS_2 PF13347.1 KUM61762.1 - 1.6e-07 30.1 13.4 1.6e-07 30.1 9.3 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein PUCC PF03209.10 KUM61762.1 - 7.1e-05 21.7 3.3 0.00013 20.8 2.3 1.4 1 0 0 1 1 1 1 PUCC protein STE PF02200.11 KUM61763.1 - 8.7e-60 199.6 0.1 1.5e-59 198.9 0.1 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.21 KUM61763.1 - 7.4e-12 44.8 13.4 1.6e-06 28.0 0.4 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KUM61763.1 - 4e-10 39.2 10.3 0.00015 21.8 0.7 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KUM61763.1 - 6.1e-10 38.8 12.5 1.6e-09 37.5 2.9 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 KUM61763.1 - 0.0059 16.4 0.2 0.039 13.8 0.0 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-TRAF PF02176.13 KUM61763.1 - 0.008 16.5 2.1 0.015 15.6 1.5 1.4 1 0 0 1 1 1 1 TRAF-type zinc finger zf-C2H2_jaz PF12171.3 KUM61763.1 - 0.095 12.8 4.3 1.6 8.9 0.0 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 KUM61763.1 - 0.12 12.0 4.9 2.1 8.1 0.2 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-Di19 PF05605.7 KUM61763.1 - 0.18 11.9 2.7 0.46 10.6 1.9 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding GMC_oxred_N PF00732.14 KUM61765.1 - 1.3e-58 198.5 0.0 1.7e-58 198.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KUM61765.1 - 5.1e-36 124.1 0.0 1.1e-35 123.0 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KUM61765.1 - 0.0019 18.2 0.0 0.0052 16.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KUM61765.1 - 0.012 14.4 0.1 0.28 9.9 0.2 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.1 KUM61765.1 - 0.02 14.9 0.0 3.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KUM61765.1 - 0.031 13.2 0.0 0.34 9.7 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KUM61765.1 - 0.051 13.4 0.1 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CoA_transf_3 PF02515.12 KUM61766.1 - 2.4e-50 170.4 0.0 3.1e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III RNA_pol_I_A49 PF06870.7 KUM61768.1 - 8.8e-49 166.0 0.0 5.2e-35 120.7 0.0 2.7 2 1 0 2 2 2 2 A49-like RNA polymerase I associated factor MFS_1 PF07690.11 KUM61769.1 - 4.1e-35 121.1 32.9 5.4e-35 120.7 21.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L41 PF05162.8 KUM61769.1 - 8e-08 31.8 28.6 1.7e-07 30.7 19.8 1.6 1 0 0 1 1 1 1 Ribosomal protein L41 DUF2370 PF10176.4 KUM61769.1 - 0.88 8.8 2.8 16 4.7 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) Acyl_transf_3 PF01757.17 KUM61769.1 - 2.8 6.7 38.5 0.03 13.1 9.4 3.1 2 1 1 3 3 3 0 Acyltransferase family Aminotran_1_2 PF00155.16 KUM61771.1 - 7.4e-86 288.3 0.0 9.4e-86 288.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KUM61771.1 - 2e-06 26.3 0.0 3.4e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KUM61771.1 - 1.4e-05 24.0 0.0 2.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KUM61771.1 - 0.0011 18.0 0.2 0.0035 16.4 0.1 1.8 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KUM61771.1 - 0.019 14.1 0.1 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase DUF3405 PF11885.3 KUM61771.1 - 0.11 10.7 0.0 0.17 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) ADH_N PF08240.7 KUM61772.1 - 3.2e-28 97.6 0.9 6.8e-28 96.5 0.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM61772.1 - 5.5e-25 87.4 0.6 5.5e-25 87.4 0.4 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KUM61772.1 - 0.00051 20.9 0.1 0.00094 20.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KUM61772.1 - 0.035 13.2 0.3 0.062 12.4 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SNF2_N PF00176.18 KUM61773.1 - 2.2e-71 240.1 2.4 4.5e-71 239.0 1.6 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 KUM61773.1 - 3.3e-52 176.2 23.1 3.3e-52 176.2 16.0 4.3 4 0 0 4 4 4 1 DNA-binding domain Helicase_C PF00271.26 KUM61773.1 - 1.3e-16 60.2 0.0 3.9e-16 58.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ank_5 PF13857.1 KUM61773.1 - 0.026 14.7 0.1 0.067 13.4 0.1 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) AA_permease_2 PF13520.1 KUM61775.1 - 3.7e-53 180.6 28.7 4.4e-53 180.3 19.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM61775.1 - 2.5e-09 35.9 29.5 5.1e-09 34.9 20.4 1.5 1 1 0 1 1 1 1 Amino acid permease MIG-14_Wnt-bd PF06664.7 KUM61775.1 - 0.044 12.6 0.7 0.12 11.1 0.5 1.8 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Baculo_11_kDa PF06143.6 KUM61775.1 - 4.4 6.7 5.5 8.1 5.8 0.2 3.1 3 0 0 3 3 3 0 Baculovirus 11 kDa family Na_H_Exchanger PF00999.16 KUM61776.1 - 4.8e-62 209.6 35.3 5.9e-62 209.3 24.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Pex14_N PF04695.8 KUM61776.1 - 0.097 12.7 1.5 10 6.1 0.0 2.7 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Dioxygenase_C PF00775.16 KUM61777.1 - 4.5e-13 48.8 0.2 5.2e-10 38.8 0.0 2.8 2 1 0 2 2 2 2 Dioxygenase AAA_17 PF13207.1 KUM61778.1 - 2.8e-06 28.1 0.0 6.2e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 KUM61778.1 - 1e-05 25.1 0.0 2e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 KUM61778.1 - 0.00011 22.4 0.0 0.00039 20.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KUM61778.1 - 0.0058 16.9 0.1 0.022 15.0 0.1 1.9 1 1 0 1 1 1 1 ABC transporter AAA_33 PF13671.1 KUM61778.1 - 0.013 15.3 0.0 0.032 14.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain CPT PF07931.7 KUM61778.1 - 0.02 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_21 PF13304.1 KUM61778.1 - 0.023 14.6 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KUM61778.1 - 0.026 14.4 0.0 0.066 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KUM61778.1 - 0.033 14.5 0.0 0.068 13.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KUM61778.1 - 0.082 12.8 0.1 0.69 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain KTI12 PF08433.5 KUM61778.1 - 0.087 12.0 0.0 0.17 11.0 0.0 1.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 T2SE PF00437.15 KUM61778.1 - 0.14 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 KUM61778.1 - 0.36 10.3 0.0 0.36 10.3 0.0 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain Drf_GBD PF06371.8 KUM61781.1 - 6.4e-18 64.7 2.8 4.2e-11 42.5 0.0 2.6 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain Xpo1 PF08389.7 KUM61781.1 - 0.024 14.5 0.0 0.51 10.2 0.0 2.3 2 0 0 2 2 2 0 Exportin 1-like protein Nramp PF01566.13 KUM61783.1 - 6.4e-95 317.9 19.2 6.4e-95 317.9 13.3 1.6 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Snf7 PF03357.16 KUM61785.1 - 3.2e-42 143.8 15.0 3.9e-42 143.5 10.4 1.0 1 0 0 1 1 1 1 Snf7 DUF4201 PF13870.1 KUM61785.1 - 5.5e-05 22.6 6.2 5.5e-05 22.6 4.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) NPV_P10 PF05531.7 KUM61785.1 - 0.0012 19.1 7.3 0.045 13.9 0.8 2.7 3 0 0 3 3 3 2 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.3 KUM61785.1 - 0.0035 14.7 5.6 0.0044 14.4 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 KUM61785.1 - 0.0092 15.1 4.8 0.054 12.6 0.5 2.0 1 1 1 2 2 2 1 Reovirus sigma C capsid protein Atg14 PF10186.4 KUM61785.1 - 0.017 14.0 7.8 0.023 13.6 5.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CDC37_N PF03234.9 KUM61785.1 - 0.042 14.1 6.9 0.057 13.7 4.8 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF1395 PF07160.7 KUM61785.1 - 0.048 13.1 5.8 0.35 10.3 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1395) IncA PF04156.9 KUM61785.1 - 0.12 11.9 5.6 0.23 11.0 0.4 2.2 1 1 1 2 2 2 0 IncA protein Glutaredoxin PF00462.19 KUM61785.1 - 0.14 12.1 1.1 0.29 11.1 0.2 1.9 2 0 0 2 2 2 0 Glutaredoxin DUF342 PF03961.8 KUM61785.1 - 0.43 8.9 7.9 1 7.7 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 KUM61785.1 - 0.45 10.1 11.1 1.6 8.3 7.7 1.8 1 1 0 1 1 1 0 Mnd1 family Mod_r PF07200.8 KUM61785.1 - 0.46 10.4 10.3 0.11 12.4 3.9 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein BLOC1_2 PF10046.4 KUM61785.1 - 0.46 10.6 7.5 5.2 7.2 1.5 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec34 PF04136.10 KUM61785.1 - 0.77 9.4 5.6 1 9.0 2.4 1.9 1 1 0 2 2 2 0 Sec34-like family DUF4337 PF14235.1 KUM61785.1 - 2.2 8.0 7.6 0.34 10.7 1.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) DUF4140 PF13600.1 KUM61785.1 - 2.8 8.4 5.7 5.9 7.3 0.0 3.2 2 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) Uso1_p115_C PF04871.8 KUM61785.1 - 2.8 7.8 13.6 9.2 6.2 9.4 1.9 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region FliD_N PF02465.13 KUM61785.1 - 3.9 7.8 10.0 26 5.2 4.1 2.9 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus SlyX PF04102.7 KUM61785.1 - 7.3 7.0 8.3 2.8e+02 1.9 0.1 3.6 1 1 1 2 2 2 0 SlyX APG6 PF04111.7 KUM61785.1 - 9.2 5.2 11.2 5.8 5.8 6.0 1.7 1 1 1 2 2 2 0 Autophagy protein Apg6 Shikimate_DH PF01488.15 KUM61786.1 - 0.075 13.1 0.0 0.079 13.0 0.0 1.1 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 KUM61786.1 - 0.11 12.3 0.1 0.13 12.1 0.1 1.0 1 0 0 1 1 1 0 short chain dehydrogenase Thiolase_N PF00108.18 KUM61788.1 - 2.1e-77 259.6 2.0 2.1e-77 259.6 1.4 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KUM61788.1 - 8.7e-45 151.1 0.3 2.3e-44 149.7 0.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KUM61788.1 - 0.0079 15.6 2.1 0.036 13.5 0.5 2.5 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KUM61788.1 - 0.034 13.8 0.7 13 5.5 0.0 2.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.5 KUM61788.1 - 0.059 13.3 0.0 0.2 11.6 0.0 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Glyco_hydro_43 PF04616.9 KUM61789.1 - 9.9e-70 234.8 3.3 1.4e-69 234.3 2.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Acetyltransf_2 PF00797.12 KUM61790.1 - 4.4e-18 65.7 0.0 4.9e-18 65.5 0.0 1.0 1 0 0 1 1 1 1 N-acetyltransferase Beta_helix PF13229.1 KUM61792.1 - 3.9e-07 29.9 21.1 0.0043 16.8 4.7 2.3 1 1 1 2 2 2 2 Right handed beta helix region Glyco_hydro_28 PF00295.12 KUM61792.1 - 3.2e-06 26.3 2.5 4.4e-06 25.8 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.2 KUM61792.1 - 0.00091 19.4 9.6 0.85 9.6 6.7 3.0 1 1 0 1 1 1 1 Pectate lyase superfamily protein Methyltransf_6 PF03737.10 KUM61793.1 - 3.7e-22 78.8 0.2 5.8e-22 78.2 0.2 1.4 1 1 0 1 1 1 1 Demethylmenaquinone methyltransferase MOZ_SAS PF01853.13 KUM61796.1 - 7.3e-79 263.3 0.0 1.1e-78 262.7 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family Med3 PF11593.3 KUM61796.1 - 0.015 14.5 0.2 0.015 14.5 0.1 2.3 1 1 0 2 2 2 0 Mediator complex subunit 3 fungal Velvet PF11754.3 KUM61797.1 - 0.0071 15.9 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Velvet factor Complex1_51K PF01512.12 KUM61798.1 - 5.9e-46 155.9 0.0 9.3e-46 155.2 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 KUM61798.1 - 2.5e-18 64.9 0.7 4.8e-18 64.0 0.5 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 KUM61798.1 - 5.4e-09 35.8 0.0 1.3e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 SLBB domain TRI12 PF06609.8 KUM61799.1 - 0.14 10.2 0.0 0.21 9.7 0.0 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) SET PF00856.23 KUM61799.1 - 0.18 12.0 0.0 0.48 10.7 0.0 1.7 1 0 0 1 1 1 0 SET domain SAPS PF04499.10 KUM61800.1 - 1.7e-203 676.5 0.2 1.3e-201 670.4 0.0 2.6 2 1 0 2 2 2 2 SIT4 phosphatase-associated protein SDA1 PF05285.7 KUM61800.1 - 0.51 9.5 25.7 0.31 10.2 2.4 4.3 3 1 1 4 4 4 0 SDA1 Glyco_hydro_26 PF02156.10 KUM61801.1 - 4.6e-76 256.2 1.1 5.3e-76 256.0 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 Peptidase_C97 PF05903.9 KUM61802.1 - 0.00016 21.4 0.0 0.00025 20.8 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 KUM61802.1 - 0.015 15.2 0.1 0.47 10.4 0.0 2.5 2 1 0 2 2 2 0 Lecithin retinol acyltransferase Nup96 PF12110.3 KUM61803.1 - 7.8e-91 304.1 0.4 1.5e-90 303.2 0.1 1.6 2 0 0 2 2 2 1 Nuclear protein 96 Nucleoporin2 PF04096.9 KUM61803.1 - 6.5e-47 158.8 0.0 1e-46 158.2 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 KUM61803.1 - 4e-09 36.6 107.3 1.7e-07 31.4 33.6 10.6 5 2 5 10 10 10 3 Nucleoporin FG repeat region CRISPR_Cas2 PF09827.4 KUM61803.1 - 0.53 10.4 0.0 1.3 9.1 0.0 1.6 1 0 0 1 1 1 0 CRISPR associated protein Cas2 MFS_1 PF07690.11 KUM61804.1 - 4.4e-49 167.0 28.0 5.1e-49 166.8 12.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KUM61804.1 - 0.0012 17.1 4.3 0.0018 16.5 3.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 KUM61804.1 - 7.1 6.5 9.6 15 5.4 0.1 3.2 3 0 0 3 3 3 0 MFS_1 like family DUF3445 PF11927.3 KUM61805.1 - 1e-83 280.5 0.0 1.3e-83 280.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Exo5 PF09810.4 KUM61806.1 - 1.2e-123 412.4 0.0 1.5e-123 412.1 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 KUM61806.1 - 0.0039 16.6 0.3 0.68 9.2 0.2 2.8 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Mpv17_PMP22 PF04117.7 KUM61807.1 - 2.7e-18 65.3 0.7 2.7e-18 65.3 0.5 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family MFS_1 PF07690.11 KUM61808.1 - 4.7e-38 130.8 48.7 1.4e-37 129.2 30.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C3H1 PF10650.4 KUM61809.1 - 0.17 11.3 1.6 0.32 10.5 0.1 2.0 2 0 0 2 2 2 0 Putative zinc-finger domain Histone PF00125.19 KUM61810.1 - 1.1e-31 108.7 0.4 1.8e-31 108.0 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KUM61810.1 - 2.9e-06 27.3 0.0 4.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KUM61810.1 - 0.0035 17.3 0.3 0.0073 16.3 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KUM61810.1 - 0.04 13.6 0.1 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 KUM61811.1 - 1.6e-15 56.9 0.1 1.9e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KUM61811.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 KUM61811.1 - 0.00012 22.1 0.1 0.00018 21.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KUM61811.1 - 0.00017 21.5 0.1 0.0003 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KUM61811.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KUM61811.1 - 0.022 14.0 0.0 0.022 13.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T zf-C2H2 PF00096.21 KUM61812.1 - 7.6e-09 35.4 18.4 5.5e-05 23.2 0.7 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KUM61812.1 - 2.4e-07 30.6 18.2 0.00063 19.8 0.6 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-BED PF02892.10 KUM61812.1 - 0.26 11.0 5.8 0.095 12.4 1.8 1.9 2 0 0 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.1 KUM61812.1 - 0.4 11.0 14.4 1.2 9.6 1.1 4.4 4 0 0 4 4 4 0 Zinc-finger double domain zf-Di19 PF05605.7 KUM61812.1 - 0.72 10.0 7.1 3.7 7.7 1.5 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding RRN7 PF11781.3 KUM61812.1 - 0.86 9.1 2.8 2.4 7.7 0.5 2.2 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Sulfotransfer_3 PF13469.1 KUM61814.1 - 0.0025 18.7 0.1 0.005 17.7 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase family DUF2890 PF11081.3 KUM61815.1 - 0.027 14.5 3.3 0.041 13.9 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) P2 PF07194.6 KUM61815.1 - 0.097 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 P2 response regulator binding domain Clat_adaptor_s PF01217.15 KUM61816.1 - 7.5e-56 187.7 2.0 8.7e-56 187.5 1.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Cys_Met_Meta_PP PF01053.15 KUM61817.1 - 9.3e-62 208.5 0.0 2.8e-61 206.9 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KUM61817.1 - 0.00092 18.3 0.0 0.098 11.6 0.0 2.6 3 0 0 3 3 3 2 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 KUM61817.1 - 0.0033 16.4 0.0 0.0066 15.4 0.0 1.6 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KUM61817.1 - 0.01 14.6 0.0 0.022 13.5 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class-V Ist1 PF03398.9 KUM61818.1 - 2.4e-49 166.9 1.0 2.9e-24 85.3 3.1 2.3 2 0 0 2 2 2 2 Regulator of Vps4 activity in the MVB pathway PsbJ PF01788.12 KUM61819.1 - 0.013 15.0 0.1 0.018 14.5 0.1 1.2 1 0 0 1 1 1 0 PsbJ DUF3169 PF11368.3 KUM61819.1 - 0.023 13.9 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF3959 PF13105.1 KUM61819.1 - 0.1 11.9 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Fungal_trans_2 PF11951.3 KUM61820.1 - 3.7e-36 124.5 0.4 5.4e-36 124.0 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM61820.1 - 5.3e-07 29.4 10.2 1.2e-06 28.2 7.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cutinase PF01083.17 KUM61821.1 - 2.2e-34 118.7 1.7 3.5e-34 118.0 1.2 1.3 1 0 0 1 1 1 1 Cutinase LCM PF04072.9 KUM61821.1 - 9.9e-20 70.8 0.0 1.5e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase PE-PPE PF08237.6 KUM61821.1 - 0.0012 18.3 0.1 0.0021 17.5 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 KUM61821.1 - 0.08 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_6 PF12697.2 KUM61821.1 - 0.092 12.6 2.1 0.29 10.9 0.0 2.4 3 1 0 3 3 3 0 Alpha/beta hydrolase family SUN PF03856.8 KUM61822.1 - 4.6e-81 271.7 8.0 6.7e-81 271.2 5.5 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Tmemb_cc2 PF10267.4 KUM61822.1 - 5.2 5.5 7.9 7.6 5.0 5.5 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein ORC6 PF05460.8 KUM61822.1 - 6.7 5.7 28.7 9.5 5.2 19.9 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Glyco_transf_22 PF03901.12 KUM61823.1 - 2.1e-83 280.7 21.1 2.4e-83 280.4 14.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Gar1 PF04410.9 KUM61824.1 - 4.4e-46 156.1 0.2 4.4e-46 156.1 0.2 3.0 3 0 0 3 3 3 1 Gar1/Naf1 RNA binding region PRP3 PF08572.5 KUM61825.1 - 4.8e-68 228.8 11.7 4.8e-68 228.8 8.1 2.0 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 KUM61825.1 - 8.7e-37 125.6 0.0 1.9e-36 124.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RNA_pol_Rpb1_5 PF04998.12 KUM61826.1 - 1.5e-86 290.1 0.0 5.4e-86 288.2 0.0 2.0 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KUM61826.1 - 3.4e-62 209.2 1.5 4e-62 209.0 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KUM61826.1 - 5.5e-32 110.6 0.0 2.3e-30 105.4 0.0 3.2 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 KUM61826.1 - 6.9e-29 101.1 0.5 3.6e-22 79.0 0.0 3.4 3 0 0 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 KUM61826.1 - 2.8e-16 59.1 0.0 2.8e-16 59.1 0.0 2.8 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 4 ADH_N PF08240.7 KUM61828.1 - 3.2e-29 100.8 0.1 6e-29 99.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM61828.1 - 9.2e-20 70.5 0.0 1.4e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KUM61828.1 - 0.029 14.0 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated DUF1227 PF06777.6 KUM61829.1 - 4.9e-63 211.1 0.7 1.2e-62 209.9 0.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 KUM61829.1 - 2.5e-51 173.5 0.1 5e-51 172.5 0.1 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 KUM61829.1 - 3e-44 150.9 0.0 7.3e-44 149.6 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain SNF2_N PF00176.18 KUM61829.1 - 0.0014 17.4 0.0 0.0057 15.4 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 KUM61829.1 - 0.002 17.6 0.0 0.33 10.4 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KUM61829.1 - 0.0057 16.7 0.8 1.2 9.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.1 KUM61829.1 - 0.0061 16.1 0.2 0.021 14.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KUM61829.1 - 0.013 15.3 0.0 0.08 12.7 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.11 KUM61829.1 - 0.048 12.8 0.1 3.1 6.9 0.0 3.0 3 0 0 3 3 3 0 PhoH-like protein NACHT PF05729.7 KUM61829.1 - 0.074 12.7 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.4 KUM61829.1 - 0.11 11.4 0.5 3.3 6.6 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) Stomoxyn PF11585.3 KUM61829.1 - 0.2 11.5 0.1 0.41 10.4 0.1 1.5 1 0 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn zf-RING_2 PF13639.1 KUM61830.1 - 1.3e-07 31.2 8.2 2.8e-07 30.2 5.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KUM61830.1 - 1.8e-07 31.1 2.0 4.8e-07 29.8 1.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 KUM61830.1 - 4.7e-05 23.2 6.2 0.00012 22.0 4.3 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 KUM61830.1 - 0.00011 21.9 2.2 0.00028 20.6 1.5 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 KUM61830.1 - 0.00026 20.5 9.6 0.00065 19.3 6.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 KUM61830.1 - 0.034 14.2 7.8 0.078 13.0 5.4 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.1 KUM61830.1 - 0.04 13.9 9.0 0.1 12.6 6.2 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 KUM61830.1 - 0.052 13.2 5.9 0.12 12.0 4.1 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_3 PF13920.1 KUM61830.1 - 0.14 11.8 6.2 0.29 10.8 4.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KUM61830.1 - 0.15 11.6 6.0 7.2 6.2 4.1 2.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 KUM61830.1 - 2.5 8.1 7.2 5.5 7.0 5.0 1.6 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 KUM61830.1 - 4.8 6.9 7.0 9.4 6.0 4.9 1.5 1 0 0 1 1 1 0 PHD-finger MFS_1 PF07690.11 KUM61831.1 - 1.8e-48 165.0 61.8 2.3e-47 161.4 42.0 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM61831.1 - 6.3e-24 84.1 11.1 1.1e-23 83.3 7.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KUM61831.1 - 1.1e-13 50.6 16.5 1.1e-13 50.6 11.4 3.4 1 1 2 3 3 3 2 Sugar (and other) transporter OATP PF03137.15 KUM61831.1 - 0.034 12.2 18.0 0.013 13.6 1.5 3.3 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Ribosomal_L35Ae PF01247.13 KUM61835.1 - 1.8e-42 143.0 0.4 2.7e-42 142.4 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 KUM61835.1 - 0.003 17.4 0.0 1 9.3 0.0 2.3 2 0 0 2 2 2 2 RimM N-terminal domain MFS_2 PF13347.1 KUM61837.1 - 1.8e-15 56.2 10.8 1.8e-15 56.2 7.5 2.0 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 KUM61837.1 - 0.049 13.4 0.0 0.049 13.4 0.0 3.5 4 0 0 4 4 4 0 MFS_1 like family G6PD_C PF02781.11 KUM61838.1 - 1.7e-137 457.1 0.0 2.9e-137 456.3 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 KUM61838.1 - 4.1e-66 222.7 0.1 6.7e-66 222.0 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF3226 PF11536.3 KUM61838.1 - 0.051 13.0 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) F-box-like PF12937.2 KUM61839.1 - 1.1e-07 31.3 0.1 0.0015 18.2 0.0 3.1 3 0 0 3 3 3 2 F-box-like Cytokin_check_N PF10407.4 KUM61839.1 - 0.0038 16.8 0.0 0.0092 15.5 0.0 1.6 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus EF-hand_1 PF00036.27 KUM61840.1 - 1.5e-22 77.1 0.2 2.6e-08 32.5 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 KUM61840.1 - 1.3e-19 68.2 2.3 0.00012 21.6 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 KUM61840.1 - 8.4e-19 66.9 0.9 6.9e-09 35.1 0.0 3.7 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_7 PF13499.1 KUM61840.1 - 9.4e-19 67.3 0.6 1e-07 31.9 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KUM61840.1 - 1.3e-14 52.7 3.4 0.00024 20.2 0.1 3.8 4 0 0 4 4 4 3 EF hand EF-hand_10 PF14788.1 KUM61840.1 - 0.1 12.2 0.0 33 4.2 0.0 3.1 3 0 0 3 3 3 0 EF hand Ank_2 PF12796.2 KUM61842.1 - 7.5e-88 289.0 17.6 1.1e-17 64.1 0.1 5.6 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KUM61842.1 - 1.1e-55 182.7 20.9 2e-07 30.4 0.0 10.2 10 0 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.1 KUM61842.1 - 1.8e-38 130.2 6.9 2.9e-08 33.9 0.0 7.4 3 1 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM61842.1 - 3.3e-37 122.8 10.8 8.4e-05 22.4 0.0 10.1 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.1 KUM61842.1 - 3.6e-36 122.3 13.7 3e-08 33.6 0.1 8.7 3 1 6 9 9 9 8 Ankyrin repeats (many copies) Radical_SAM PF04055.16 KUM61843.1 - 1.8e-14 54.2 0.0 2.9e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily HAD PF12710.2 KUM61844.1 - 3.3e-16 60.0 0.0 4.9e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KUM61844.1 - 1.6e-11 45.0 0.1 4.4e-10 40.3 0.6 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KUM61844.1 - 5.9e-11 42.4 0.1 3.6e-08 33.3 0.0 2.9 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KUM61844.1 - 1.6e-07 31.7 0.0 3.2e-06 27.4 0.0 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF705 PF05152.7 KUM61844.1 - 0.025 13.5 0.1 0.039 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) Put_Phosphatase PF06888.7 KUM61844.1 - 0.059 12.5 0.1 1.4 8.0 0.1 2.3 2 1 0 2 2 2 0 Putative Phosphatase Hydrolase_like PF13242.1 KUM61844.1 - 0.13 11.9 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like PAPS_reduct PF01507.14 KUM61845.1 - 4.4e-42 143.8 0.0 6.1e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family zf-MYND PF01753.13 KUM61846.1 - 1e-07 31.6 7.7 1e-07 31.6 5.3 1.8 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.11 KUM61846.1 - 9.9 5.9 9.5 79 3.0 6.6 2.4 1 1 0 1 1 1 0 HIT zinc finger GRP PF07172.6 KUM61847.1 - 0.00013 22.3 2.4 0.00017 21.9 1.7 1.1 1 0 0 1 1 1 1 Glycine rich protein family DUF2763 PF10961.3 KUM61847.1 - 0.0096 16.2 12.6 0.05 14.0 8.7 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2763) DeoC PF01791.4 KUM61848.1 - 2.9e-47 160.9 0.7 3.5e-47 160.7 0.5 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.16 KUM61848.1 - 0.057 12.3 1.2 0.087 11.7 0.8 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase CbiX PF01903.12 KUM61848.1 - 0.072 13.2 0.1 0.21 11.7 0.1 1.8 1 0 0 1 1 1 0 CbiX WD40 PF00400.27 KUM61849.1 - 1.2e-13 50.3 10.5 1.1e-06 28.3 0.2 5.4 6 0 0 6 6 6 2 WD domain, G-beta repeat PQQ_2 PF13360.1 KUM61849.1 - 0.0021 17.5 1.3 0.01 15.2 0.2 2.4 1 1 2 3 3 3 1 PQQ-like domain PQQ_3 PF13570.1 KUM61849.1 - 0.089 13.1 5.3 1.3 9.4 0.0 3.6 3 1 1 4 4 4 0 PQQ-like domain TBPIP PF07106.8 KUM61849.1 - 0.091 12.3 8.0 0.14 11.7 5.5 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) End3 PF12761.2 KUM61849.1 - 0.25 10.9 8.2 0.8 9.3 5.7 1.8 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 GAS PF13851.1 KUM61849.1 - 0.34 10.0 10.7 0.49 9.5 7.4 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.3 KUM61849.1 - 0.53 7.5 15.1 0.66 7.2 10.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Gon7 PF08738.5 KUM61849.1 - 0.74 9.8 7.4 1.9 8.5 5.2 1.7 1 1 0 1 1 1 0 Gon7 family IncA PF04156.9 KUM61849.1 - 0.82 9.2 7.0 1.3 8.6 4.8 1.2 1 0 0 1 1 1 0 IncA protein CorA PF01544.13 KUM61849.1 - 0.86 8.5 2.9 1.3 7.9 2.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TMF_TATA_bd PF12325.3 KUM61849.1 - 1.3 8.7 11.2 2.9 7.6 7.0 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding APG6 PF04111.7 KUM61849.1 - 2.5 7.0 7.9 3.8 6.4 5.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Cep57_CLD_2 PF14197.1 KUM61849.1 - 2.5 8.0 11.9 4.6 7.2 8.2 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF972 PF06156.8 KUM61849.1 - 5.8 7.3 7.0 11 6.4 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) GFA PF04828.9 KUM61851.1 - 1.1e-23 83.0 0.5 1.4e-23 82.6 0.3 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme SRF-TF PF00319.13 KUM61852.1 - 3.3e-23 80.6 0.1 4.8e-23 80.1 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF1708 PF08101.6 KUM61853.1 - 4.4e-127 424.3 0.0 5.9e-127 423.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DUF1708 PF08101.6 KUM61854.1 - 0.041 12.7 0.0 0.051 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) DUF1237 PF06824.6 KUM61855.1 - 0.0069 15.0 0.1 0.01 14.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Aminotran_1_2 PF00155.16 KUM61856.1 - 8e-41 140.1 0.0 9.9e-41 139.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2670 PF10875.3 KUM61856.1 - 0.04 13.9 0.0 1.8 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2670) Aminotran_3 PF00202.16 KUM61856.1 - 0.17 10.6 0.0 0.27 10.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-III SIMPL PF04402.9 KUM61857.1 - 1.1e-18 67.8 0.0 1.3e-18 67.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) DUF3254 PF11630.3 KUM61857.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3254) adh_short PF00106.20 KUM61858.1 - 7.3e-26 91.0 0.9 9.5e-26 90.6 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM61858.1 - 1.3e-14 54.2 0.2 1.9e-14 53.7 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KUM61858.1 - 5.7e-12 45.9 0.0 7.9e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 KUM61858.1 - 1.1e-07 31.0 0.0 1.4e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KUM61858.1 - 1.7e-05 24.3 0.1 2.6e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DJ-1_PfpI PF01965.19 KUM61860.1 - 7.5e-24 83.8 0.1 1.5e-23 82.8 0.1 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 KUM61860.1 - 1.5e-19 69.2 0.1 4.2e-19 67.7 0.1 1.8 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family Peptidase_C26 PF07722.8 KUM61860.1 - 0.027 13.9 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase C26 DUF4066 PF13278.1 KUM61860.1 - 0.064 12.5 0.0 0.094 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative amidotransferase PCI PF01399.22 KUM61861.1 - 1.6e-21 76.5 0.9 3.9e-21 75.3 0.0 2.1 2 0 0 2 2 2 1 PCI domain Ku_PK_bind PF08785.6 KUM61861.1 - 0.0076 16.1 0.1 0.036 13.9 0.1 2.2 1 0 0 1 1 1 1 Ku C terminal domain like ERp29 PF07749.7 KUM61861.1 - 4.1 8.0 8.6 0.64 10.6 0.1 3.3 3 0 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain FSH1 PF03959.8 KUM61862.1 - 4.2e-45 153.7 0.0 5e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KUM61862.1 - 8.8e-08 32.0 0.0 1.2e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KUM61862.1 - 2.9e-05 24.0 0.9 0.00024 21.0 0.6 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KUM61862.1 - 0.00032 20.0 0.1 0.041 13.1 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 KUM61862.1 - 0.0038 16.7 0.1 0.9 8.9 0.2 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase TP_methylase PF00590.15 KUM61863.1 - 2.1e-46 158.2 0.1 3.4e-46 157.5 0.1 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 KUM61863.1 - 1.4e-14 54.1 0.0 2.9e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KUM61863.1 - 1e-10 40.7 0.1 6.6e-07 28.5 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal DDE_Tnp_ISL3 PF01610.12 KUM61863.1 - 0.048 13.2 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 Transposase CW_binding_2 PF04122.7 KUM61863.1 - 0.11 12.6 0.0 0.49 10.6 0.0 2.0 2 0 0 2 2 2 0 Putative cell wall binding repeat 2 RTA1 PF04479.8 KUM61865.1 - 3.1e-30 105.3 8.9 4.2e-30 104.9 6.1 1.1 1 0 0 1 1 1 1 RTA1 like protein Tautomerase_3 PF14832.1 KUM61865.1 - 0.028 14.4 0.1 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative oxalocrotonate tautomerase enzyme Abhydrolase_6 PF12697.2 KUM61866.1 - 5.8e-24 85.2 2.2 6.9e-24 84.9 1.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM61866.1 - 4.4e-14 52.4 0.5 6e-14 52.0 0.4 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM61866.1 - 1.4e-06 28.0 0.1 4.3e-06 26.4 0.0 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.15 KUM61866.1 - 4.6e-05 23.7 0.0 6.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.15 KUM61866.1 - 0.0041 16.5 0.0 0.0062 16.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Lipase_3 PF01764.20 KUM61866.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF2305 PF10230.4 KUM61866.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Hydrolase_4 PF12146.3 KUM61866.1 - 0.14 12.0 0.1 0.4 10.5 0.0 1.8 1 0 0 1 1 1 0 Putative lysophospholipase DIOX_N PF14226.1 KUM61867.1 - 1.9e-17 63.8 0.0 3.7e-17 62.9 0.0 1.6 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KUM61867.1 - 5.2e-15 55.5 0.0 9.5e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KUM61868.1 - 6.9e-20 71.7 0.0 1.1e-19 71.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KUM61868.1 - 6.4e-13 48.8 0.0 1.2e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Acyl_transf_1 PF00698.16 KUM61869.1 - 1.2e-57 195.6 0.0 1.2e-56 192.3 0.0 2.2 2 0 0 2 2 2 1 Acyl transferase domain MaoC_dehydratas PF01575.14 KUM61869.1 - 2.3e-26 91.6 0.0 4.6e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 KUM61869.1 - 1.3e-25 88.9 0.0 2.9e-25 87.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 KUM61869.1 - 4.1e-14 52.4 0.0 2e-13 50.2 0.0 2.1 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NMO PF03060.10 KUM61869.1 - 0.0004 19.6 0.1 0.0018 17.4 0.1 2.1 1 1 0 1 1 1 1 Nitronate monooxygenase Herpes_UL33 PF03581.8 KUM61869.1 - 0.15 12.0 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus UL33-like protein Beta_elim_lyase PF01212.16 KUM61870.1 - 9.3e-59 198.9 0.1 1.1e-58 198.6 0.1 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KUM61870.1 - 0.0034 16.3 0.0 0.0057 15.6 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KUM61870.1 - 0.087 11.8 0.1 0.43 9.5 0.0 1.9 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 KUM61870.1 - 0.13 10.4 0.0 0.2 9.8 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme ABC_tran PF00005.22 KUM61871.1 - 2.3e-58 196.3 0.0 3.2e-32 111.6 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KUM61871.1 - 2.8e-35 122.0 25.3 6e-22 78.3 6.4 2.7 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 KUM61871.1 - 5.4e-10 39.6 0.1 0.059 13.3 0.0 4.4 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 KUM61871.1 - 1.7e-09 37.2 0.4 0.1 11.8 0.4 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KUM61871.1 - 5.5e-09 36.2 0.1 0.00089 19.2 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KUM61871.1 - 6.9e-09 35.9 0.1 0.0016 18.6 0.0 3.3 3 1 0 3 3 2 2 AAA domain AAA_29 PF13555.1 KUM61871.1 - 8.5e-09 34.8 0.1 0.0029 17.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KUM61871.1 - 2.4e-08 34.8 0.0 0.0046 17.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KUM61871.1 - 2.6e-07 30.6 0.0 0.0059 16.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KUM61871.1 - 5.5e-07 28.9 0.0 0.0067 15.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KUM61871.1 - 6.1e-07 29.9 0.0 0.004 17.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KUM61871.1 - 1.7e-06 28.3 0.0 0.0078 16.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 KUM61871.1 - 4.3e-06 25.8 0.1 0.28 9.9 0.0 3.7 3 1 0 3 3 3 1 NB-ARC domain MobB PF03205.9 KUM61871.1 - 9.8e-06 25.3 0.1 0.17 11.6 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 KUM61871.1 - 1.6e-05 23.9 0.0 0.15 10.9 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA PF00004.24 KUM61871.1 - 5.7e-05 23.3 0.2 0.043 14.0 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KUM61871.1 - 0.00014 21.3 0.1 0.43 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KUM61871.1 - 0.00015 21.7 0.0 0.7 9.8 0.0 2.9 3 0 0 3 3 2 2 50S ribosome-binding GTPase RNA_helicase PF00910.17 KUM61871.1 - 0.00018 21.6 0.0 0.61 10.2 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Miro PF08477.8 KUM61871.1 - 0.00022 21.7 0.0 0.26 11.8 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_14 PF13173.1 KUM61871.1 - 0.0013 18.5 0.0 2.5 8.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.16 KUM61871.1 - 0.0014 17.7 0.0 0.17 11.0 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.4 KUM61871.1 - 0.0019 17.7 0.7 1.8 8.0 0.0 2.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 KUM61871.1 - 0.0022 17.5 0.1 1.3 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain FtsK_SpoIIIE PF01580.13 KUM61871.1 - 0.003 17.0 0.0 0.13 11.6 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_28 PF13521.1 KUM61871.1 - 0.0033 17.3 0.6 1.1 9.1 0.2 2.5 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 KUM61871.1 - 0.0036 17.0 0.2 1.1 8.9 0.0 3.0 3 0 0 3 3 2 1 NTPase PDR_assoc PF08370.6 KUM61871.1 - 0.004 16.6 0.3 0.012 15.1 0.2 1.8 1 0 0 1 1 1 1 Plant PDR ABC transporter associated NACHT PF05729.7 KUM61871.1 - 0.0054 16.4 0.1 1.1 8.8 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_5 PF07728.9 KUM61871.1 - 0.0066 16.1 0.1 3.2 7.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 KUM61871.1 - 0.0075 15.4 0.1 3.3 6.7 0.0 3.1 3 0 0 3 3 3 0 KaiC IstB_IS21 PF01695.12 KUM61871.1 - 0.0075 15.6 0.1 6.1 6.2 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein PRK PF00485.13 KUM61871.1 - 0.012 15.1 0.1 3.2 7.2 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.1 KUM61871.1 - 0.014 14.9 0.1 4.6 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KUM61871.1 - 0.017 14.8 0.0 0.21 11.2 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_30 PF13604.1 KUM61871.1 - 0.017 14.6 0.1 4 6.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 KUM61871.1 - 0.018 14.5 0.1 1.7 8.1 0.0 2.9 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Dynamin_N PF00350.18 KUM61871.1 - 0.022 14.5 0.3 3.2 7.5 0.0 2.7 2 1 0 2 2 2 0 Dynamin family Septin PF00735.13 KUM61871.1 - 0.023 13.6 0.0 4.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Septin SbcCD_C PF13558.1 KUM61871.1 - 0.026 14.4 0.7 0.41 10.6 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 KUM61871.1 - 0.027 13.5 0.0 2.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.12 KUM61871.1 - 0.028 14.2 0.1 1.1 9.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 ATP_bind_1 PF03029.12 KUM61871.1 - 0.032 13.7 0.1 2.7 7.4 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_ATPase PF09818.4 KUM61871.1 - 0.1 11.1 2.0 12 4.2 0.1 3.3 4 0 0 4 4 4 0 Predicted ATPase of the ABC class Adeno_IVa2 PF02456.10 KUM61871.1 - 0.14 10.7 0.0 6.5 5.3 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein APS_kinase PF01583.15 KUM61871.1 - 0.18 11.4 0.0 0.79 9.3 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase Pox_A32 PF04665.7 KUM61871.1 - 0.2 10.9 0.5 12 5.1 0.0 2.6 3 0 0 3 3 2 0 Poxvirus A32 protein Guanylate_kin PF00625.16 KUM61871.1 - 0.31 10.4 0.0 11 5.3 0.0 2.6 2 0 0 2 2 2 0 Guanylate kinase Rad17 PF03215.10 KUM61871.1 - 0.76 8.3 0.9 1.5 7.4 0.0 1.7 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein p450 PF00067.17 KUM61873.1 - 2.3e-58 197.8 0.0 3.1e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 P5CR_dimer PF14748.1 KUM61875.1 - 5.1e-16 58.6 7.0 8.8e-16 57.8 4.8 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KUM61875.1 - 7.4e-12 45.5 0.0 2.2e-11 44.0 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 KUM61875.1 - 1.1e-06 28.4 0.0 1.9e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 KUM61875.1 - 0.023 13.6 0.4 0.038 12.9 0.0 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase ketoacyl-synt PF00109.21 KUM61876.1 - 4.4e-18 65.6 0.9 6.3e-18 65.1 0.1 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 KUM61876.1 - 3.8e-17 62.8 0.0 7.7e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 KUM61876.1 - 3.3e-12 46.3 0.1 2e-11 43.7 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 KUM61876.1 - 0.14 11.1 0.0 0.28 10.1 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain Aminotran_4 PF01063.14 KUM61877.1 - 8.9e-18 64.6 0.0 1.1e-17 64.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV 2OG-FeII_Oxy PF03171.15 KUM61878.1 - 1.4e-11 44.5 0.0 2.5e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.23 KUM61879.1 - 0 1328.2 0.0 8e-83 278.1 0.0 5.3 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.15 KUM61879.1 - 1.2e-162 539.8 0.0 4.6e-36 124.2 0.0 7.3 6 1 1 7 7 7 6 Condensation domain PP-binding PF00550.20 KUM61879.1 - 6.8e-50 167.2 7.1 8.9e-09 35.4 0.0 6.4 5 0 0 5 5 5 5 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 KUM61879.1 - 2.5e-05 24.5 0.0 0.75 10.1 0.0 4.1 4 0 0 4 4 4 2 HxxPF-repeated domain 4HBT_2 PF13279.1 KUM61880.1 - 1.3e-07 32.1 0.0 1.9e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Abhydrolase_6 PF12697.2 KUM61881.1 - 1.4e-09 38.1 0.0 2.7e-09 37.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM61881.1 - 0.00022 20.9 0.1 0.0014 18.3 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM61881.1 - 0.019 14.5 0.0 0.038 13.5 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold HLH PF00010.21 KUM61882.1 - 2.2e-12 46.4 0.6 5.4e-12 45.2 0.0 2.0 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain adh_short PF00106.20 KUM61883.1 - 3.4e-06 27.0 0.1 1.2e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase Allantoicase PF03561.10 KUM61883.1 - 0.055 12.9 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 Allantoicase repeat ADH_zinc_N PF00107.21 KUM61884.1 - 3e-12 46.2 1.9 1.7e-10 40.5 0.3 3.0 3 1 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM61884.1 - 4.5e-05 23.1 0.0 0.02 14.6 0.0 2.5 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KUM61884.1 - 5.9e-05 23.9 0.0 0.00025 21.9 0.0 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KUM61884.1 - 0.09 12.7 0.6 0.15 12.0 0.4 1.3 1 0 0 1 1 1 0 NADH(P)-binding AlaDh_PNT_C PF01262.16 KUM61884.1 - 0.12 11.9 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 KUM61884.1 - 0.14 12.3 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.11 KUM61885.1 - 2.3e-42 144.9 58.4 2.3e-42 144.9 40.5 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.13 KUM61886.1 - 2.7e-10 39.9 11.3 4.3e-10 39.3 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KUM61886.1 - 1.3e-07 30.7 0.2 2.6e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.2 KUM61887.1 - 3.1e-13 50.1 0.0 4.3e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM61887.1 - 6.2e-12 45.4 0.0 8.9e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KUM61887.1 - 5.2e-06 26.0 0.0 7.4e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 KUM61887.1 - 2.1e-05 24.3 0.0 3.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.7 KUM61887.1 - 7e-05 21.4 0.0 0.00012 20.6 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 KUM61887.1 - 0.00038 19.7 0.0 0.00065 18.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KUM61887.1 - 0.0034 16.9 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1100 PF06500.6 KUM61887.1 - 0.016 13.7 0.0 0.032 12.8 0.0 1.4 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1100) DLH PF01738.13 KUM61887.1 - 0.042 13.1 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Hydrolase_4 PF12146.3 KUM61887.1 - 0.063 13.1 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase ketoacyl-synt PF00109.21 KUM61888.1 - 6.1e-61 206.1 0.1 1.1e-60 205.2 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KUM61888.1 - 1.5e-54 184.4 0.2 5.5e-54 182.5 0.2 2.1 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 KUM61888.1 - 5e-52 176.8 0.0 8.8e-52 176.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KUM61888.1 - 4.8e-50 170.7 0.1 8.3e-50 169.9 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 KUM61888.1 - 6.9e-40 136.6 0.5 3.8e-39 134.2 0.3 2.4 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KUM61888.1 - 4.4e-33 113.6 0.9 2.9e-32 110.9 0.8 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KUM61888.1 - 9e-20 70.5 0.0 2.1e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KUM61888.1 - 2.1e-14 54.5 0.0 7.4e-14 52.7 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 KUM61888.1 - 9.6e-06 25.7 0.0 2.4e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 KUM61888.1 - 7e-05 22.5 0.9 0.00017 21.2 0.6 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III PF08545.5 KUM61888.1 - 0.0024 17.4 0.2 0.31 10.7 0.0 3.7 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DNA_gyraseB_C PF00986.16 KUM61888.1 - 0.33 10.7 0.0 1.3 8.8 0.0 2.0 2 0 0 2 2 2 0 DNA gyrase B subunit, carboxyl terminus DUF663 PF04950.7 KUM61889.1 - 4.8e-92 308.0 0.0 4.8e-92 308.0 0.0 3.1 2 1 1 3 3 3 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KUM61889.1 - 1.3e-25 88.7 0.0 3.4e-25 87.3 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 KUM61889.1 - 6.8e-06 25.6 0.0 0.0019 17.6 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KUM61889.1 - 8e-06 26.0 0.0 1.8e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KUM61889.1 - 2.6e-05 24.3 0.1 8.8e-05 22.5 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain AAA_17 PF13207.1 KUM61889.1 - 0.00036 21.3 0.0 0.00036 21.3 0.0 4.6 3 1 1 4 4 1 1 AAA domain MMR_HSR1 PF01926.18 KUM61889.1 - 0.00043 20.2 0.0 0.0011 18.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 KUM61889.1 - 0.00045 20.5 1.0 0.001 19.3 0.0 2.1 2 0 0 2 2 1 1 ABC transporter NACHT PF05729.7 KUM61889.1 - 0.00059 19.5 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.1 KUM61889.1 - 0.0006 19.7 0.0 0.0016 18.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KUM61889.1 - 0.00071 19.2 0.6 0.0017 18.0 0.1 1.8 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 KUM61889.1 - 0.0018 18.7 0.0 0.0061 17.0 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA PF00004.24 KUM61889.1 - 0.0019 18.4 0.0 0.0046 17.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KUM61889.1 - 0.0035 16.7 0.5 0.0094 15.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.1 KUM61889.1 - 0.0042 16.6 0.1 0.011 15.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KUM61889.1 - 0.0043 16.9 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KUM61889.1 - 0.0051 15.9 1.7 0.0083 15.2 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 KUM61889.1 - 0.0054 16.4 0.2 0.013 15.2 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain cobW PF02492.14 KUM61889.1 - 0.0078 15.6 0.1 0.014 14.8 0.1 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 KUM61889.1 - 0.012 15.3 0.3 0.025 14.3 0.2 1.5 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.17 KUM61889.1 - 0.012 14.4 0.0 0.03 13.1 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain SRPRB PF09439.5 KUM61889.1 - 0.019 14.2 0.0 0.04 13.1 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RNA_helicase PF00910.17 KUM61889.1 - 0.021 14.9 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.9 KUM61889.1 - 0.022 13.7 0.4 0.042 12.8 0.0 1.6 2 0 0 2 2 2 0 KAP family P-loop domain DUF258 PF03193.11 KUM61889.1 - 0.03 13.5 0.0 0.054 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 KUM61889.1 - 0.043 13.5 0.1 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 KUM61889.1 - 0.044 13.2 0.0 0.22 11.0 0.0 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.1 KUM61889.1 - 0.73 9.7 0.0 0.73 9.7 0.0 3.0 2 1 1 3 3 3 0 AAA domain AAA_11 PF13086.1 KUM61889.1 - 1.4 8.4 5.5 1.5 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain UQ_con PF00179.21 KUM61891.1 - 8.2e-25 86.8 0.1 9.1e-25 86.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KUM61891.1 - 1.9e-06 27.6 0.0 3.2e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KUM61891.1 - 2.7e-05 24.0 0.0 3.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 RWD domain Aminotran_1_2 PF00155.16 KUM61892.1 - 1.7e-19 70.0 0.0 2e-19 69.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KUM61892.1 - 0.12 10.8 0.0 0.18 10.2 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase RNase_Zc3h12a PF11977.3 KUM61892.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain DUF3455 PF11937.3 KUM61893.1 - 1.5e-42 145.5 0.1 2e-42 145.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) SF3b1 PF08920.5 KUM61894.1 - 6.2e-29 100.9 0.0 1.4e-28 99.7 0.0 1.6 1 0 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 KUM61894.1 - 2e-16 60.0 3.4 0.017 15.3 0.0 7.4 6 3 4 10 10 10 6 HEAT repeats HEAT_EZ PF13513.1 KUM61894.1 - 1.2e-10 41.5 1.5 0.75 10.3 0.0 7.6 7 2 2 9 9 9 3 HEAT-like repeat HEAT PF02985.17 KUM61894.1 - 3.7e-10 39.0 10.2 0.57 10.3 0.0 9.3 10 0 0 10 10 10 2 HEAT repeat Vac14_Fab1_bd PF12755.2 KUM61894.1 - 2.9e-05 24.3 0.3 4.3 7.7 0.0 4.9 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 KUM61894.1 - 0.0031 17.3 0.2 25 4.6 0.0 4.6 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 UNC45-central PF11701.3 KUM61894.1 - 0.0044 16.6 0.1 0.031 13.9 0.0 2.5 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.3 KUM61894.1 - 0.13 11.5 0.1 1.5 8.1 0.0 2.7 4 0 0 4 4 4 0 CLASP N terminal zf-H2C2_2 PF13465.1 KUM61895.1 - 8.6e-12 44.7 14.5 5.9e-06 26.3 0.2 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KUM61895.1 - 6.2e-10 38.8 11.6 1.8e-05 24.7 3.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KUM61895.1 - 2.5e-07 30.5 8.3 0.00019 21.5 1.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KUM61895.1 - 5.6e-06 26.3 1.5 1.8e-05 24.7 1.0 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KUM61895.1 - 5.3e-05 23.2 5.7 0.00011 22.2 1.4 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KUM61895.1 - 0.00017 21.4 6.9 0.0037 17.1 1.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KUM61895.1 - 0.055 13.5 1.0 0.055 13.5 0.7 1.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 KUM61895.1 - 0.67 9.7 5.1 0.24 11.1 0.5 2.2 2 0 0 2 2 2 0 BED zinc finger zf-C2HC_2 PF13913.1 KUM61895.1 - 1.8 8.3 6.2 5.6 6.7 0.2 2.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.1 KUM61895.1 - 4.4 7.7 8.7 6.1 7.2 1.2 3.2 2 1 1 3 3 3 0 C2H2-type zinc-finger domain FAD_binding_2 PF00890.19 KUM61896.1 - 5e-27 94.7 0.1 6.6e-27 94.3 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KUM61896.1 - 0.006 15.5 0.1 0.013 14.3 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.14 KUM61896.1 - 0.0076 15.4 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 KUM61896.1 - 0.0091 15.8 0.0 0.027 14.3 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SNARE PF05739.14 KUM61897.1 - 0.0041 16.7 2.0 0.0041 16.7 1.4 2.4 2 0 0 2 2 2 1 SNARE domain PGC7_Stella PF15549.1 KUM61897.1 - 0.8 9.6 10.4 0.3 11.0 3.2 2.2 1 1 0 2 2 2 0 PGC7/Stella/Dppa3 domain Sec1 PF00995.18 KUM61898.1 - 1.5e-128 429.8 0.0 1.8e-128 429.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Pkinase PF00069.20 KUM61900.1 - 2e-71 240.2 0.0 2.6e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM61900.1 - 1.9e-35 122.2 0.0 2.9e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM61900.1 - 0.00013 21.0 0.0 0.00021 20.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KUM61900.1 - 0.00086 18.6 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 KUM61900.1 - 0.0056 15.7 0.0 0.0094 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KUM61900.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Telomere_reg-2 PF10193.4 KUM61903.1 - 1.3e-33 115.6 0.0 5.9e-32 110.3 0.0 2.8 2 0 0 2 2 2 1 Telomere length regulation protein Ebola_NP PF05505.7 KUM61903.1 - 0.18 9.8 3.8 0.28 9.2 2.6 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein APH PF01636.18 KUM61905.1 - 0.00011 21.9 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KUM61905.1 - 0.05 13.1 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase PPK2 PF03976.9 KUM61906.1 - 0.042 13.1 0.1 0.042 13.1 0.1 1.0 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) Pkinase PF00069.20 KUM61908.1 - 1.1e-57 195.1 0.0 1.5e-57 194.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM61908.1 - 2.1e-42 145.0 0.0 3.2e-42 144.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM61908.1 - 3.7e-06 26.1 0.0 6.3e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KUM61908.1 - 0.0018 18.0 0.0 0.012 15.3 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KUM61908.1 - 0.0026 16.8 0.0 0.006 15.6 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KUM61908.1 - 0.082 12.2 0.1 0.31 10.3 0.1 1.9 1 1 0 1 1 1 0 RIO1 family GTP_EFTU PF00009.22 KUM61909.1 - 9.3e-61 204.5 0.0 1.3e-60 204.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KUM61909.1 - 1.3e-38 131.2 0.0 3.1e-38 130.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KUM61909.1 - 2.9e-22 78.3 0.0 1.2e-21 76.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.1 KUM61909.1 - 1.4e-12 47.2 0.0 4.2e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KUM61909.1 - 6.7e-12 45.3 0.1 7.6e-11 41.9 0.1 2.7 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KUM61909.1 - 7.5e-05 22.6 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PWI PF01480.12 KUM61910.1 - 1.2e-08 34.9 0.4 3e-08 33.6 0.0 1.8 2 0 0 2 2 2 1 PWI domain RRM_6 PF14259.1 KUM61910.1 - 1.5e-08 34.4 0.1 9.3e-08 31.9 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KUM61910.1 - 8.3e-07 28.5 0.3 0.0001 21.8 0.1 2.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM61910.1 - 9e-07 28.6 0.0 2.2e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KUM61910.1 - 1.6e-05 24.6 0.0 0.0026 17.4 0.0 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 KUM61910.1 - 0.01 15.4 1.7 0.019 14.6 1.2 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Borrelia_P83 PF05262.6 KUM61910.1 - 5.7 5.0 13.9 8.3 4.5 9.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Methyltransf_24 PF13578.1 KUM61911.1 - 6.7e-14 52.6 0.0 1e-13 52.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 KUM61911.1 - 1e-09 37.7 0.0 2.9e-09 36.2 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase DUF1442 PF07279.6 KUM61911.1 - 9.7e-06 24.8 0.0 1.3e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1442) Methyltransf_18 PF12847.2 KUM61911.1 - 8.1e-05 23.1 0.0 0.00021 21.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KUM61911.1 - 0.028 14.4 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Sir1 PF11603.3 KUM61911.1 - 0.05 13.7 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 Regulatory protein Sir1 Fungal_trans PF04082.13 KUM61912.1 - 4.5e-15 55.2 0.3 6.3e-15 54.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KUM61914.1 - 2.4e-30 105.4 15.2 3.2e-30 105.0 10.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM61914.1 - 1.1e-10 40.4 3.4 1.3e-10 40.1 2.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KUM61914.1 - 5.1e-10 38.5 8.6 6.9e-10 38.0 6.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_Mycoplasma PF07672.8 KUM61914.1 - 0.028 13.5 8.0 0.023 13.9 0.8 2.2 1 1 1 2 2 2 0 Mycoplasma MFS transporter MFS_1 PF07690.11 KUM61915.1 - 3e-05 22.9 5.7 3e-05 22.9 3.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KUM61915.1 - 0.03 12.7 6.7 0.032 12.6 4.7 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein DUF1049 PF06305.6 KUM61915.1 - 6.4 6.3 8.6 5.4 6.5 1.3 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1049) Pkinase PF00069.20 KUM61917.1 - 0.012 14.7 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain HEAT PF02985.17 KUM61918.1 - 4.1e-10 38.8 1.2 0.023 14.7 0.0 5.0 5 0 0 5 5 5 3 HEAT repeat Cnd1 PF12717.2 KUM61918.1 - 0.00032 20.5 0.0 0.0046 16.8 0.0 2.1 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KUM61918.1 - 0.0011 19.3 0.1 1.9 9.0 0.0 3.4 2 1 0 2 2 2 2 HEAT-like repeat Adaptin_N PF01602.15 KUM61918.1 - 0.0016 16.8 0.0 0.0022 16.3 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KUM61918.1 - 0.0096 16.1 0.0 0.098 12.9 0.0 2.6 1 1 1 2 2 2 1 HEAT repeats CoA_trans PF01144.18 KUM61918.1 - 0.028 13.6 0.0 0.079 12.1 0.0 1.7 2 0 0 2 2 2 0 Coenzyme A transferase Ipi1_N PF12333.3 KUM61918.1 - 0.093 12.7 0.0 0.42 10.5 0.0 2.0 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation B56 PF01603.15 KUM61918.1 - 0.25 9.8 0.0 18 3.7 0.0 2.3 1 1 1 2 2 2 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF3425 PF11905.3 KUM61919.1 - 3.3e-35 120.9 0.2 7.8e-35 119.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KUM61919.1 - 0.0011 18.8 13.1 0.37 10.7 4.3 3.5 3 1 1 4 4 4 2 bZIP transcription factor Herpes_UL6 PF01763.11 KUM61919.1 - 0.25 9.4 3.5 0.33 9.0 2.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like bZIP_2 PF07716.10 KUM61919.1 - 1.8 8.4 9.8 1.8 8.4 2.1 2.5 2 0 0 2 2 2 0 Basic region leucine zipper MFS_1 PF07690.11 KUM61920.1 - 8.9e-49 166.0 40.6 8.9e-49 166.0 28.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM61920.1 - 3.4e-12 45.6 31.0 6.4e-12 44.7 21.5 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 KUM61920.1 - 0.0053 14.8 0.9 0.0053 14.8 0.6 2.2 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family DUF3464 PF11947.3 KUM61920.1 - 0.21 11.0 1.5 0.39 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) zf-MYND PF01753.13 KUM61921.1 - 1.1e-09 38.0 12.4 1.8e-09 37.3 8.6 1.4 1 0 0 1 1 1 1 MYND finger FYVE_2 PF02318.11 KUM61921.1 - 0.07 13.0 2.6 0.14 12.0 1.8 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger APH PF01636.18 KUM61922.1 - 3.4e-07 30.2 0.0 6.5e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KUM61922.1 - 0.038 13.1 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Chromate_transp PF02417.10 KUM61924.1 - 6e-34 117.0 29.2 4.6e-30 104.4 7.6 2.7 3 0 0 3 3 3 2 Chromate transporter Amino_oxidase PF01593.19 KUM61926.1 - 1.7e-38 132.9 0.0 2.6e-37 128.9 0.0 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KUM61926.1 - 4.3e-11 42.6 0.2 8.1e-11 41.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KUM61926.1 - 1.4e-09 37.3 0.3 2.4e-05 23.4 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KUM61926.1 - 5.1e-06 25.6 0.2 0.051 12.4 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KUM61926.1 - 6.7e-06 26.3 0.1 0.0007 19.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KUM61926.1 - 2.9e-05 24.3 0.4 9.6e-05 22.7 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KUM61926.1 - 9.1e-05 21.6 0.2 0.0004 19.5 0.1 2.0 3 0 0 3 3 3 1 Thi4 family HI0933_like PF03486.9 KUM61926.1 - 0.00031 19.3 0.7 0.0049 15.4 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KUM61926.1 - 0.0007 18.5 1.6 0.0015 17.4 0.8 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 KUM61926.1 - 0.0016 17.5 0.5 0.0034 16.5 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KUM61926.1 - 0.0038 17.1 0.3 0.014 15.2 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM61926.1 - 0.0067 16.2 0.3 0.11 12.2 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 KUM61926.1 - 0.015 14.3 0.7 0.023 13.8 0.5 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 KUM61926.1 - 0.065 12.0 0.9 0.11 11.2 0.6 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A AMP-binding PF00501.23 KUM61927.1 - 1.7e-33 115.6 0.0 7.1e-33 113.6 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KUM61927.1 - 2.2e-29 102.1 0.0 3.5e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KUM61927.1 - 4.9e-10 39.2 0.0 8.7e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KUM61927.1 - 2.5e-09 37.2 0.1 7.6e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site HHH_5 PF14520.1 KUM61927.1 - 0.16 12.1 0.1 0.75 10.0 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain DUF1129 PF06570.6 KUM61928.1 - 1.5 8.0 4.7 4 6.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) FAD_binding_4 PF01565.18 KUM61929.1 - 1.9e-11 43.5 0.5 1.9e-11 43.5 0.3 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KUM61929.1 - 3.6e-07 29.9 0.1 8.2e-07 28.8 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like MIP PF00230.15 KUM61930.1 - 2.7e-31 108.8 3.9 3.5e-31 108.4 2.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF606 PF04657.8 KUM61930.1 - 0.031 14.3 3.8 0.087 12.9 0.0 2.8 2 1 0 3 3 3 0 Protein of unknown function, DUF606 Gly-zipper_Omp PF13488.1 KUM61930.1 - 0.71 9.5 3.5 8 6.1 0.0 3.2 3 0 0 3 3 3 0 Glycine zipper CD24 PF14984.1 KUM61931.1 - 5.2 6.9 7.1 7.9 6.3 4.9 1.3 1 0 0 1 1 1 0 CD24 protein DUF4646 PF15496.1 KUM61932.1 - 0.019 15.0 1.2 0.12 12.3 0.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4646) UBN2_3 PF14244.1 KUM61933.1 - 0.048 13.2 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Acetyltransf_1 PF00583.19 KUM61935.1 - 1.4e-13 50.6 0.1 2.3e-13 49.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KUM61935.1 - 8.5e-07 28.6 0.0 1.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KUM61935.1 - 0.0012 18.9 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KUM61935.1 - 0.0069 16.2 0.3 0.011 15.5 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KUM61935.1 - 0.046 13.8 0.0 0.077 13.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PAP2_3 PF14378.1 KUM61935.1 - 0.11 11.9 0.5 0.3 10.5 0.3 1.6 2 0 0 2 2 2 0 PAP2 superfamily MFS_1 PF07690.11 KUM61936.1 - 5.1e-30 104.3 37.1 9.7e-30 103.4 20.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KUM61936.1 - 4.5e-07 28.4 2.1 4.5e-07 28.4 1.5 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KUM61936.1 - 3.5e-06 25.8 18.4 3.5e-06 25.8 12.7 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter Mod_r PF07200.8 KUM61938.1 - 0.00066 19.6 6.3 0.001 18.9 4.3 1.3 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein IncA PF04156.9 KUM61938.1 - 0.0013 18.3 3.3 0.014 14.9 1.6 2.0 2 0 0 2 2 2 1 IncA protein LCD1 PF09798.4 KUM61938.1 - 0.0029 15.6 4.8 0.0042 15.1 3.3 1.1 1 0 0 1 1 1 1 DNA damage checkpoint protein FliJ PF02050.11 KUM61938.1 - 0.01 15.9 5.5 0.017 15.1 3.8 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein HAUS-augmin3 PF14932.1 KUM61938.1 - 0.032 13.4 5.4 0.048 12.8 3.7 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 APG6 PF04111.7 KUM61938.1 - 0.036 13.1 7.0 0.048 12.7 4.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 CENP-Q PF13094.1 KUM61938.1 - 0.05 13.6 6.4 0.14 12.2 4.5 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF848 PF05852.6 KUM61938.1 - 0.063 13.1 3.0 0.13 12.0 2.1 1.5 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4140 PF13600.1 KUM61938.1 - 0.074 13.5 5.7 0.18 12.2 0.6 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Pepsin-I3 PF06394.8 KUM61938.1 - 0.074 12.7 0.9 0.18 11.4 0.6 1.6 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain FadA PF09403.5 KUM61938.1 - 0.11 12.5 3.4 0.27 11.2 2.5 1.5 2 0 0 2 2 1 0 Adhesion protein FadA Seryl_tRNA_N PF02403.17 KUM61938.1 - 0.12 12.3 4.9 0.21 11.6 2.9 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Slp PF03843.8 KUM61938.1 - 0.18 10.7 0.7 0.61 9.0 0.1 2.0 2 0 0 2 2 2 0 Outer membrane lipoprotein Slp family DUF4201 PF13870.1 KUM61938.1 - 0.4 10.0 9.7 0.57 9.6 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Striatin PF08232.7 KUM61938.1 - 0.59 10.4 5.5 0.44 10.8 1.9 2.0 1 1 0 1 1 1 0 Striatin family ADIP PF11559.3 KUM61938.1 - 0.66 9.8 11.7 1.3 8.9 7.9 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding TMF_TATA_bd PF12325.3 KUM61938.1 - 0.78 9.4 6.6 6.1 6.6 1.3 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF904 PF06005.7 KUM61938.1 - 1.2 9.5 8.2 0.11 12.8 2.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Bap31 PF05529.7 KUM61938.1 - 1.6 8.1 4.5 2.8 7.3 3.1 1.5 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like GAS PF13851.1 KUM61938.1 - 1.7 7.8 10.5 6.1 5.9 6.1 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Cep57_CLD_2 PF14197.1 KUM61938.1 - 2.9 7.9 10.7 8.1 6.4 0.7 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Atg14 PF10186.4 KUM61938.1 - 5 5.9 10.9 5.9 5.7 7.0 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 KUM61938.1 - 9.6 5.7 10.6 2.4 7.7 3.6 2.1 1 1 0 2 2 2 0 Septum formation initiator WD40 PF00400.27 KUM61939.1 - 1.4e-45 151.5 15.5 7.8e-12 44.5 0.1 7.6 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 KUM61939.1 - 3.5e-06 25.4 7.6 0.39 8.7 0.1 4.8 3 1 0 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 KUM61939.1 - 0.018 14.7 1.2 0.1 12.2 0.0 2.5 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 KUM61939.1 - 0.13 10.4 0.0 0.21 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Hira PF07569.6 KUM61939.1 - 0.15 11.2 0.7 2.4 7.2 0.0 2.9 2 1 2 4 4 4 0 TUP1-like enhancer of split LsmAD PF06741.8 KUM61940.1 - 1.3e-26 92.4 2.4 3.8e-26 90.9 1.6 1.8 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 KUM61940.1 - 1.3e-16 60.2 0.0 2.7e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain AIP3 PF03915.8 KUM61941.1 - 1.9e-156 521.2 0.7 1.9e-156 521.2 0.5 2.0 2 0 0 2 2 2 1 Actin interacting protein 3 Lectin_N PF03954.9 KUM61941.1 - 0.0015 17.9 0.1 0.0015 17.9 0.1 2.5 4 0 0 4 4 4 1 Hepatic lectin, N-terminal domain Mito_carr PF00153.22 KUM61942.1 - 1.5e-66 220.1 1.6 9.5e-23 79.7 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF515 PF04415.7 KUM61942.1 - 3.6 5.7 4.9 5.5 5.1 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Tctex-1 PF03645.8 KUM61943.1 - 1.5e-33 114.7 0.0 1.7e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family NLE PF08154.7 KUM61943.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 NLE (NUC135) domain Msg2_C PF12373.3 KUM61944.1 - 0.18 11.0 0.2 0.56 9.4 0.0 2.0 2 0 0 2 2 2 0 Major surface glycoprotein 2 C terminal tRNA-synt_1g PF09334.6 KUM61945.1 - 5.4e-100 334.8 0.0 2.8e-99 332.4 0.0 2.0 2 1 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KUM61945.1 - 8.3e-16 57.1 0.0 6.5e-12 44.2 0.0 3.4 2 2 2 4 4 4 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 KUM61945.1 - 1.3e-06 27.8 0.0 0.0057 15.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 KUM61945.1 - 0.00035 20.3 0.0 0.00065 19.4 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA PALP PF00291.20 KUM61946.1 - 5.8e-49 166.9 1.2 7e-49 166.7 0.3 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Ish1 PF10281.4 KUM61947.1 - 8.1e-05 22.6 0.0 0.00011 22.1 0.0 1.2 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein DUF1470 PF07336.6 KUM61947.1 - 0.0048 17.2 1.1 0.0068 16.7 0.7 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1470) SAM_2 PF07647.12 KUM61947.1 - 0.036 13.9 0.1 0.069 13.0 0.0 1.5 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF4129 PF13559.1 KUM61947.1 - 0.091 12.7 0.3 0.15 12.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) DUF3487 PF11990.3 KUM61947.1 - 0.14 11.5 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) NTF2 PF02136.15 KUM61948.1 - 5.6e-05 23.4 0.2 0.00012 22.4 0.1 1.6 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 KUM61948.1 - 0.00017 21.3 0.0 0.0017 18.1 0.0 1.9 2 0 0 2 2 2 1 Nuclear pore RNA shuttling protein Mtr2 DUF924 PF06041.6 KUM61949.1 - 2.7e-48 164.2 0.0 5e-48 163.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) S_layer_N PF05123.7 KUM61949.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 S-layer like family, N-terminal region Fungal_trans_2 PF11951.3 KUM61950.1 - 3.3e-22 78.6 2.2 1.4e-14 53.4 0.5 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM61950.1 - 5.4e-08 32.6 8.4 9.5e-08 31.8 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PPTA PF01239.17 KUM61951.1 - 2.2e-39 131.1 19.6 3.4e-08 32.4 0.0 5.6 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_19 PF14559.1 KUM61951.1 - 0.031 14.6 0.0 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KUM61951.1 - 0.047 14.3 1.1 3.3 8.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4269 PF14091.1 KUM61951.1 - 0.13 12.1 0.1 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4269) Sulfatase PF00884.18 KUM61952.1 - 3e-19 69.3 0.4 1.2e-18 67.4 0.2 1.9 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KUM61952.1 - 9.9e-08 31.6 0.3 3.5e-07 29.8 0.0 1.9 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KUM61952.1 - 0.0026 16.2 0.0 0.0037 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Ribosomal_L38e PF01781.13 KUM61954.1 - 8.6e-33 111.9 1.8 9.8e-33 111.7 1.3 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Pox_A3L PF05288.6 KUM61954.1 - 0.089 12.5 0.1 2.9 7.6 0.0 2.1 2 0 0 2 2 2 0 Poxvirus A3L Protein TPR_21 PF09976.4 KUM61955.1 - 0.078 12.9 0.8 0.15 12.0 0.5 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat DSBA PF01323.15 KUM61956.1 - 3.3e-19 69.2 0.0 3.7e-19 69.0 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain DUF1641 PF07849.6 KUM61956.1 - 0.079 12.5 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) cobW PF02492.14 KUM61958.1 - 2.1e-38 131.5 0.0 3.4e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 KUM61958.1 - 0.0064 16.1 0.0 0.031 13.9 0.0 2.0 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.9 KUM61958.1 - 0.0086 15.7 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KUM61958.1 - 0.0098 16.0 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KUM61958.1 - 0.019 14.7 0.1 0.057 13.1 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 KUM61958.1 - 0.03 14.6 0.3 0.11 12.8 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KUM61958.1 - 0.031 14.2 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Pox_A32 PF04665.7 KUM61958.1 - 0.046 13.0 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_29 PF13555.1 KUM61958.1 - 0.11 12.0 0.2 1.6 8.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain CbiA PF01656.18 KUM61958.1 - 0.12 11.7 0.2 0.91 8.8 0.1 2.5 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Viral_helicase1 PF01443.13 KUM61958.1 - 0.12 11.8 0.7 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.1 KUM61958.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Orn_Arg_deC_N PF02784.11 KUM61959.1 - 1.8e-75 253.3 0.0 2.4e-75 252.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KUM61959.1 - 1.3e-31 108.6 0.0 2.4e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 KUM61959.1 - 0.047 12.9 0.0 0.1 11.8 0.0 1.5 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Methyltransf_16 PF10294.4 KUM61961.1 - 6.5e-50 168.9 0.0 1e-49 168.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KUM61961.1 - 0.0022 18.5 0.0 0.0048 17.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KUM61961.1 - 0.021 14.1 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 KUM61961.1 - 0.048 13.6 0.1 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain GidB PF02527.10 KUM61961.1 - 0.15 11.2 0.1 0.42 9.7 0.0 1.8 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G MFS_1 PF07690.11 KUM61963.1 - 5.2e-34 117.5 24.4 5.2e-34 117.5 16.9 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily UPF0016 PF01169.14 KUM61963.1 - 0.011 15.8 0.2 2.9 8.0 0.2 2.8 2 0 0 2 2 2 0 Uncharacterized protein family UPF0016 DIOX_N PF14226.1 KUM61964.1 - 3e-18 66.4 0.0 1.1e-17 64.6 0.0 1.9 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KUM61964.1 - 2.5e-10 40.5 0.0 5.1e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3650 PF12368.3 KUM61964.1 - 0.1 12.1 0.2 0.46 10.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) FTO_CTD PF12934.2 KUM61965.1 - 0.018 14.6 0.5 0.041 13.4 0.4 1.5 1 0 0 1 1 1 0 FTO C-terminal domain TLD PF07534.11 KUM61966.1 - 1.3e-21 77.0 0.0 2.6e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 TLD Abhydrolase_5 PF12695.2 KUM61968.1 - 3.6e-11 42.9 0.1 8.3e-11 41.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KUM61968.1 - 1.2e-08 35.1 0.8 2.1e-08 34.3 0.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM61968.1 - 0.0022 17.5 0.0 0.0034 16.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KUM61968.1 - 0.0033 17.2 0.1 0.018 14.8 0.1 2.0 1 1 0 1 1 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 KUM61968.1 - 0.0035 16.9 0.1 0.0059 16.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Na_Pi_cotrans PF02690.10 KUM61968.1 - 0.01 15.5 0.3 0.018 14.7 0.2 1.3 1 0 0 1 1 1 0 Na+/Pi-cotransporter Cutinase PF01083.17 KUM61968.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.4 1 1 0 1 1 1 0 Cutinase RTA1 PF04479.8 KUM61969.1 - 1.7e-31 109.4 6.1 2.5e-31 108.9 4.3 1.2 1 0 0 1 1 1 1 RTA1 like protein Glyco_hydro_61 PF03443.9 KUM61970.1 - 1.2e-82 277.0 0.2 1.3e-82 276.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF3676 PF12429.3 KUM61970.1 - 0.18 11.3 0.0 1.8 8.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3676) Acetyltransf_3 PF13302.1 KUM61971.1 - 1.1e-24 87.1 0.0 1.5e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KUM61971.1 - 0.0063 16.4 0.1 0.25 11.2 0.3 2.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain DNA_pol_E_B PF04042.11 KUM61972.1 - 2e-48 164.4 0.0 4.1e-48 163.4 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B NMO PF03060.10 KUM61973.1 - 1.6e-71 241.2 2.4 1.8e-71 240.9 1.7 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KUM61973.1 - 4e-07 29.2 0.1 1.2e-06 27.6 0.1 1.8 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KUM61973.1 - 0.004 16.0 1.3 0.006 15.4 0.9 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ATP_synt_I PF03899.10 KUM61973.1 - 0.11 12.6 0.3 0.21 11.7 0.2 1.4 1 0 0 1 1 1 0 ATP synthase I chain Taxilin PF09728.4 KUM61974.1 - 1.1e-102 343.3 46.8 1.1e-102 343.3 32.5 1.6 2 0 0 2 2 2 1 Myosin-like coiled-coil protein DUF4201 PF13870.1 KUM61974.1 - 0.00031 20.2 16.8 0.00031 20.2 11.7 3.9 1 1 2 4 4 4 1 Domain of unknown function (DUF4201) Laminin_I PF06008.9 KUM61974.1 - 0.18 11.0 34.6 0.2 10.9 9.8 2.9 1 1 1 3 3 3 0 Laminin Domain I Myosin_tail_1 PF01576.14 KUM61974.1 - 0.64 7.6 59.1 0.25 9.0 20.3 2.2 1 1 1 2 2 2 0 Myosin tail HlyD PF00529.15 KUM61974.1 - 1.8 7.7 24.6 0.18 11.1 3.3 2.1 2 0 0 2 2 2 0 HlyD family secretion protein Laminin_II PF06009.7 KUM61974.1 - 1.8 8.2 32.1 2.7 7.7 4.5 3.8 2 2 3 5 5 5 0 Laminin Domain II ERM PF00769.14 KUM61974.1 - 2 7.8 53.4 0.024 14.1 11.2 3.4 1 1 2 3 3 3 0 Ezrin/radixin/moesin family DUF812 PF05667.6 KUM61974.1 - 3.1 6.1 46.0 2.3 6.6 10.8 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF812) Reo_sigmaC PF04582.7 KUM61974.1 - 3.7 6.6 5.2 11 5.0 1.0 2.4 2 1 0 2 2 2 0 Reovirus sigma C capsid protein TMF_TATA_bd PF12325.3 KUM61974.1 - 6.5 6.5 46.8 1.7 8.4 4.0 3.8 2 2 2 4 4 4 0 TATA element modulatory factor 1 TATA binding M16C_assoc PF08367.6 KUM61976.1 - 1.3e-54 184.7 0.3 5.4e-54 182.6 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 KUM61976.1 - 2e-23 83.0 0.0 2.5e-12 46.8 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KUM61976.1 - 2.8e-08 33.6 0.0 1.1e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Zn_clus PF00172.13 KUM61977.1 - 1.1e-05 25.2 11.0 1.7e-05 24.6 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_25 PF13649.1 KUM61978.1 - 5.2e-07 29.9 0.1 9.1e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM61978.1 - 0.0045 17.4 0.3 0.0092 16.4 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM61978.1 - 0.021 14.5 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KUM61978.1 - 0.05 13.1 2.6 0.37 10.3 1.8 2.1 1 1 0 1 1 1 0 Methyltransferase domain DUF1761 PF08570.5 KUM61980.1 - 2.2e-23 82.6 2.5 2.5e-23 82.4 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) PhaG_MnhG_YufB PF03334.9 KUM61980.1 - 0.58 10.2 0.1 0.58 10.2 0.0 2.6 3 1 0 3 3 3 0 Na+/H+ antiporter subunit QCR10 PF09796.4 KUM61980.1 - 6.1 6.5 6.7 4.3 7.0 0.4 3.0 1 1 2 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Methyltransf_16 PF10294.4 KUM61981.1 - 1.3e-50 171.2 0.0 1.6e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 KUM61981.1 - 0.00017 21.3 0.0 0.00024 20.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM61981.1 - 0.00024 20.7 0.0 0.0003 20.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 KUM61981.1 - 0.0011 17.9 0.0 0.0015 17.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_18 PF12847.2 KUM61981.1 - 0.0016 19.0 0.0 0.0024 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KUM61981.1 - 0.033 13.5 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain DUF2306 PF10067.4 KUM61982.1 - 5.9e-13 48.8 10.7 5.9e-13 48.8 7.4 2.0 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) IncA PF04156.9 KUM61982.1 - 0.31 10.6 5.0 1.4 8.4 3.9 1.9 2 1 0 2 2 2 0 IncA protein AA_permease PF00324.16 KUM61984.1 - 2.1e-98 329.7 26.8 2.5e-98 329.5 18.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KUM61984.1 - 2.3e-39 135.1 27.8 3.1e-39 134.7 19.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM61985.1 - 8.2e-08 31.0 0.6 9.6e-08 30.7 0.4 1.0 1 0 0 1 1 1 1 Amino acid permease Sdh_cyt PF01127.17 KUM61985.1 - 0.26 11.1 1.3 0.43 10.4 0.9 1.4 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit SKG6 PF08693.5 KUM61986.1 - 7.1e-07 28.4 0.0 1.6e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Herpes_gE PF02480.11 KUM61986.1 - 0.00018 19.9 0.0 0.00018 19.9 0.0 1.4 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E DUF605 PF04652.11 KUM61986.1 - 0.015 14.7 1.2 0.015 14.7 0.8 1.1 1 0 0 1 1 1 0 Vta1 like Pol_alpha_B_N PF08418.5 KUM61986.1 - 0.026 14.0 2.2 0.1 12.1 1.9 1.6 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal BatA PF07584.6 KUM61986.1 - 0.046 13.9 0.0 0.069 13.3 0.0 1.2 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Plasmodium_Vir PF05795.6 KUM61986.1 - 0.078 12.1 0.0 0.091 11.9 0.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Adeno_E3_CR2 PF02439.10 KUM61986.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Phage_HK97_TLTM PF06120.6 KUM61986.1 - 0.19 11.0 0.0 0.26 10.5 0.0 1.1 1 0 0 1 1 1 0 Tail length tape measure protein DUF202 PF02656.10 KUM61986.1 - 0.3 11.3 2.2 0.69 10.1 1.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF202) SSP160 PF06933.6 KUM61986.1 - 0.35 8.7 10.4 0.44 8.4 7.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Beta-APP PF03494.8 KUM61986.1 - 0.36 10.3 3.7 0.66 9.4 2.6 1.3 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Polysacc_synt_3 PF13440.1 KUM61987.1 - 0.024 14.1 0.4 0.024 14.1 0.3 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Orbi_NS3 PF01616.11 KUM61987.1 - 0.046 12.6 0.1 0.095 11.6 0.1 1.8 1 1 0 1 1 1 0 Orbivirus NS3 ETRAMP PF09716.5 KUM61987.1 - 0.12 12.3 0.2 1.1 9.2 0.0 2.6 4 0 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) JmjC PF02373.17 KUM61988.1 - 4.7e-08 33.2 0.3 1.9e-06 28.1 0.2 2.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 KUM61988.1 - 0.0002 21.4 9.8 0.0002 21.4 6.8 2.5 2 1 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 KUM61988.1 - 0.014 14.8 0.0 0.035 13.6 0.0 1.6 1 0 0 1 1 1 0 Cupin domain UbiA PF01040.13 KUM61989.1 - 1.1e-32 113.2 18.8 1.5e-32 112.8 13.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF2715 PF10895.3 KUM61989.1 - 0.036 13.5 0.1 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2715) Flavoprotein PF02441.14 KUM61990.1 - 1e-28 99.5 0.1 1.4e-28 99.1 0.1 1.2 1 0 0 1 1 1 1 Flavoprotein Epimerase_Csub PF13950.1 KUM61990.1 - 0.097 12.6 0.4 0.24 11.3 0.3 1.7 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit Ank_2 PF12796.2 KUM61991.1 - 7.3e-29 99.9 1.3 4.2e-10 39.8 0.0 5.0 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) SPX PF03105.14 KUM61991.1 - 8.3e-29 101.2 6.5 3e-16 60.0 0.8 2.3 1 1 1 2 2 2 2 SPX domain Ank_4 PF13637.1 KUM61991.1 - 6.2e-21 74.3 9.0 4.1e-07 30.3 0.0 6.9 4 2 5 9 9 9 5 Ankyrin repeats (many copies) Ank PF00023.25 KUM61991.1 - 2.9e-17 61.5 11.0 5.8e-05 22.6 0.1 7.8 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.1 KUM61991.1 - 6.2e-17 61.2 5.9 8.1e-05 22.7 0.0 6.2 4 2 2 6 6 6 4 Ankyrin repeats (many copies) GDPD PF03009.12 KUM61991.1 - 1e-15 57.9 0.1 8.6e-15 54.9 0.0 2.1 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_3 PF13606.1 KUM61991.1 - 9.5e-15 53.2 9.1 6.1e-05 22.8 0.0 7.1 8 0 0 8 8 8 4 Ankyrin repeat DUF1279 PF06916.8 KUM61992.1 - 4.8e-29 100.5 0.0 6.8e-29 100.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Ribosomal_L3 PF00297.17 KUM61993.1 - 6.6e-38 130.6 3.6 1.1e-36 126.5 2.5 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 Coa1 PF08695.5 KUM61994.1 - 1.2e-42 144.0 0.0 1.5e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 SKG6 PF08693.5 KUM61996.1 - 5.4e-11 41.6 3.5 3.7e-10 38.9 2.4 2.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 KUM61996.1 - 1.5e-05 24.5 0.4 2.8e-05 23.6 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) Rifin_STEVOR PF02009.11 KUM61996.1 - 8.6e-05 22.3 16.3 0.0041 16.8 11.3 2.1 1 1 0 1 1 1 1 Rifin/stevor family EphA2_TM PF14575.1 KUM61996.1 - 0.079 13.3 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF912 PF06024.7 KUM61996.1 - 0.66 10.0 5.0 0.49 10.4 0.2 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Gemini_mov PF01708.11 KUM61996.1 - 1.7 8.2 0.0 1.7 8.2 0.0 2.8 2 1 0 2 2 2 0 Geminivirus putative movement protein Peptidase_M56 PF05569.6 KUM61996.1 - 2.3 7.0 6.6 0.066 12.1 0.1 1.7 2 0 0 2 2 2 0 BlaR1 peptidase M56 DIOX_N PF14226.1 KUM61998.1 - 1.8e-12 47.7 0.0 3.1e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KUM61998.1 - 2.4e-10 40.5 0.0 4.3e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.27 KUM61999.1 - 5.3e-29 99.0 15.0 1.6e-12 46.8 0.1 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat TFIIIC_delta PF12657.2 KUM61999.1 - 4.6e-05 23.2 10.8 0.04 13.6 1.7 3.2 1 1 1 3 3 3 2 Transcription factor IIIC subunit delta N-term Sugar_tr PF00083.19 KUM62001.1 - 3.7e-106 355.3 18.0 4.6e-106 355.0 12.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM62001.1 - 1.9e-32 112.3 55.6 2e-31 109.0 19.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KUM62001.1 - 5.8e-07 28.0 3.6 5.8e-07 28.0 2.5 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 KUM62001.1 - 0.00021 21.0 1.7 0.0048 16.6 0.0 3.0 2 1 0 2 2 2 1 MFS_1 like family LacY_symp PF01306.14 KUM62001.1 - 0.00027 19.6 6.9 0.0068 15.0 0.7 2.4 2 0 0 2 2 2 2 LacY proton/sugar symporter MFS_3 PF05977.8 KUM62001.1 - 0.0006 18.0 13.0 0.0012 17.0 0.9 2.6 3 0 0 3 3 3 2 Transmembrane secretion effector PspC PF04024.7 KUM62001.1 - 0.0096 15.3 0.3 0.0096 15.3 0.2 2.8 3 0 0 3 3 3 1 PspC domain DUF788 PF05620.6 KUM62001.1 - 0.26 11.1 0.0 0.26 11.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF788) ABC_tran PF00005.22 KUM62004.1 - 1.4e-48 164.6 0.8 6.1e-23 81.6 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 KUM62004.1 - 4.6e-20 71.2 6.5 4.6e-20 71.2 4.5 3.5 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.1 KUM62004.1 - 4e-15 56.5 0.1 0.0023 17.9 0.0 4.7 4 0 0 4 4 4 3 AAA domain AAA_17 PF13207.1 KUM62004.1 - 1.5e-09 38.7 0.1 0.0018 19.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KUM62004.1 - 3.1e-09 36.4 1.4 0.16 11.1 0.0 4.5 5 0 0 5 5 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KUM62004.1 - 3.4e-06 27.2 0.0 0.017 15.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KUM62004.1 - 4.5e-06 26.5 0.1 0.082 12.8 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 KUM62004.1 - 4.8e-06 25.9 0.2 0.075 12.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KUM62004.1 - 5.8e-06 26.4 0.2 0.031 14.2 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.1 KUM62004.1 - 6.2e-06 26.5 1.8 0.075 13.3 0.0 3.1 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 KUM62004.1 - 6.5e-06 25.4 0.0 0.043 13.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 KUM62004.1 - 1.3e-05 25.6 0.0 0.032 14.7 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein MobB PF03205.9 KUM62004.1 - 1.9e-05 24.3 0.1 0.1 12.2 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 KUM62004.1 - 4.7e-05 23.4 3.7 0.025 14.5 0.0 2.8 3 0 0 3 3 2 2 AAA domain Dynamin_N PF00350.18 KUM62004.1 - 8.7e-05 22.3 1.4 0.3 10.8 0.0 3.9 4 0 0 4 4 4 1 Dynamin family AAA_15 PF13175.1 KUM62004.1 - 0.00029 20.0 7.7 0.21 10.5 0.0 4.5 5 1 0 5 5 5 2 AAA ATPase domain AAA_33 PF13671.1 KUM62004.1 - 0.0003 20.6 0.1 0.7 9.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 KUM62004.1 - 0.00034 20.3 0.3 0.63 9.6 0.0 2.9 3 0 0 3 3 2 2 NACHT domain AAA_30 PF13604.1 KUM62004.1 - 0.00079 19.0 0.1 0.051 13.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KUM62004.1 - 0.00093 19.4 0.1 0.49 10.6 0.1 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.20 KUM62004.1 - 0.0014 18.2 0.1 0.33 10.4 0.0 2.6 2 1 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.1 KUM62004.1 - 0.0016 18.8 0.1 0.024 14.9 0.0 4.8 4 1 1 5 5 4 2 AAA domain AAA_14 PF13173.1 KUM62004.1 - 0.0017 18.2 0.0 1.6 8.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KUM62004.1 - 0.0021 18.2 0.0 0.96 9.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase ArgK PF03308.11 KUM62004.1 - 0.0031 16.3 2.8 0.81 8.4 0.0 2.6 3 0 0 3 3 2 2 ArgK protein NTPase_1 PF03266.10 KUM62004.1 - 0.004 16.8 0.3 1.3 8.7 0.1 3.2 3 0 0 3 3 3 1 NTPase Zeta_toxin PF06414.7 KUM62004.1 - 0.0041 16.2 0.0 0.55 9.2 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_10 PF12846.2 KUM62004.1 - 0.0052 16.2 1.8 1.8 7.9 0.0 3.7 3 1 0 3 3 3 1 AAA-like domain AAA_5 PF07728.9 KUM62004.1 - 0.011 15.5 0.1 3.5 7.3 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 KUM62004.1 - 0.017 14.0 0.0 5.5 5.7 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.1 KUM62004.1 - 0.017 14.7 0.0 3 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KUM62004.1 - 0.019 14.8 0.3 9.2 6.2 0.1 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.17 KUM62004.1 - 0.025 14.0 0.6 0.99 8.8 0.0 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain cobW PF02492.14 KUM62004.1 - 0.029 13.8 2.2 1.3 8.3 0.2 3.1 4 0 0 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 KUM62004.1 - 0.034 13.6 0.0 10 5.5 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 KUM62004.1 - 0.045 13.1 0.0 9.4 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 KUM62004.1 - 1.7 8.3 0.0 1.7 8.3 0.0 4.2 6 0 0 6 6 5 0 Domain of unknown function DUF87 DUF4200 PF13863.1 KUM62004.1 - 2.3 8.2 18.5 0.87 9.5 0.7 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) MFS_1 PF07690.11 KUM62005.1 - 3.6e-15 55.5 69.7 1.6e-14 53.4 44.6 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM62005.1 - 0.0012 17.1 24.4 0.0018 16.5 16.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Esterase PF00756.15 KUM62006.1 - 2e-15 56.9 0.0 2.7e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 KUM62006.1 - 9.6e-06 24.9 0.0 1.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KUM62006.1 - 0.00035 20.5 0.0 0.00043 20.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM62006.1 - 0.015 15.0 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM62006.1 - 0.11 12.0 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold CTP_transf_2 PF01467.21 KUM62007.1 - 7.3e-17 61.8 0.0 7.9e-14 52.0 0.0 2.6 2 1 0 2 2 2 2 Cytidylyltransferase Glutaredoxin PF00462.19 KUM62008.1 - 8.1e-15 54.5 0.0 1.4e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin HNH_2 PF13391.1 KUM62009.1 - 0.09 12.5 0.0 0.32 10.8 0.0 1.9 2 1 0 2 2 2 0 HNH endonuclease AhpC-TSA PF00578.16 KUM62010.1 - 1.3e-22 79.8 0.0 1.8e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KUM62010.1 - 1.9e-14 53.4 0.0 2.6e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 KUM62010.1 - 0.024 14.5 0.0 0.066 13.1 0.0 1.6 1 1 0 1 1 1 0 AhpC/TSA antioxidant enzyme PRELI PF04707.9 KUM62011.1 - 8.1e-43 145.7 0.2 9.4e-43 145.4 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family BRCA-2_OB3 PF09104.5 KUM62011.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 Mpp10 PF04006.7 KUM62013.1 - 6.8e-88 295.5 60.7 9.8e-79 265.3 19.1 2.1 1 1 1 2 2 2 2 Mpp10 protein adh_short_C2 PF13561.1 KUM62014.1 - 5.9e-28 98.2 0.0 7.2e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KUM62014.1 - 1.2e-27 96.8 0.0 1.6e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM62014.1 - 9.3e-12 44.9 0.0 1.2e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KUM62014.1 - 0.0073 16.0 0.2 0.015 15.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KUM62014.1 - 0.036 13.5 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.1 KUM62017.1 - 5.8e-29 101.6 0.0 8.5e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KUM62017.1 - 2.8e-18 65.4 0.0 2.4e-17 62.3 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KUM62017.1 - 4.6e-13 48.8 0.0 2e-09 36.8 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KUM62017.1 - 6.9e-10 38.8 0.1 4e-09 36.3 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KUM62017.1 - 4.3e-07 30.0 0.0 8e-05 22.6 0.0 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KUM62017.1 - 4.6e-05 22.4 0.2 0.041 12.7 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KUM62017.1 - 0.00014 21.6 1.3 0.0034 17.1 0.4 3.3 3 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 KUM62017.1 - 0.00045 19.4 0.1 0.011 14.8 0.0 2.6 3 0 0 3 3 3 1 Thi4 family FAD_binding_2 PF00890.19 KUM62017.1 - 0.00094 18.1 0.0 0.0019 17.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KUM62017.1 - 0.013 15.9 0.2 5.4 7.4 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KUM62017.1 - 0.03 14.5 0.0 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 KUM62017.1 - 0.078 13.0 0.0 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 KUM62017.1 - 0.11 10.9 0.2 0.27 9.6 0.1 1.6 1 0 0 1 1 1 0 HI0933-like protein CPSase_L_chain PF00289.17 KUM62017.1 - 0.12 12.4 0.1 23 5.1 0.0 3.3 3 0 0 3 3 3 0 Carbamoyl-phosphate synthase L chain, N-terminal domain FAD_oxidored PF12831.2 KUM62017.1 - 0.24 10.4 1.5 0.44 9.5 0.2 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Fungal_trans PF04082.13 KUM62018.1 - 1.3e-18 66.7 0.2 2e-18 66.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM62018.1 - 1.5e-05 24.8 10.2 3.3e-05 23.6 7.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.21 KUM62019.1 - 3.7e-12 45.9 0.1 5.9e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.1 KUM62020.1 - 1.5e-27 96.9 0.0 1.8e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KUM62020.1 - 4.5e-19 68.9 1.6 5.8e-19 68.6 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Abhydrolase_3 PF07859.8 KUM62021.1 - 4.5e-46 157.0 0.0 5.8e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KUM62021.1 - 6.1e-10 38.4 4.7 8.1e-10 38.0 1.7 2.0 2 1 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.2 KUM62021.1 - 1.2e-05 25.3 0.2 1.9e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM62021.1 - 0.0013 18.4 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KUM62021.1 - 0.011 15.0 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Peptidase_S9 PF00326.16 KUM62021.1 - 0.082 12.1 0.0 7.3 5.7 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family EnY2 PF10163.4 KUM62022.1 - 0.00019 21.2 0.0 0.00034 20.4 0.0 1.4 1 0 0 1 1 1 1 Transcription factor e(y)2 RA PF00788.18 KUM62023.1 - 3.2e-16 59.5 0.0 6.2e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_2 PF07647.12 KUM62023.1 - 1.9e-14 53.2 0.0 3.8e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KUM62023.1 - 6.9e-13 48.5 0.1 1.3e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Sugar_tr PF00083.19 KUM62024.1 - 1.9e-98 330.0 24.2 2.2e-98 329.7 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM62024.1 - 2.5e-39 135.0 39.8 8.1e-34 116.8 13.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KUM62024.1 - 0.00021 21.0 3.7 0.025 14.3 0.1 3.4 2 1 1 3 3 3 2 MFS_1 like family TRI12 PF06609.8 KUM62024.1 - 0.02 13.1 6.0 0.27 9.3 1.1 2.3 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF3317 PF11779.3 KUM62024.1 - 0.023 14.1 3.6 0.14 11.6 0.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3317) ADH_N PF08240.7 KUM62025.1 - 3.8e-31 107.0 1.6 8.1e-31 106.0 1.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM62025.1 - 2.8e-21 75.4 0.1 4.7e-21 74.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KUM62025.1 - 0.00051 20.9 0.0 0.0011 19.8 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KUM62025.1 - 0.0058 16.2 0.3 0.013 15.0 0.2 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 KUM62025.1 - 0.068 12.5 0.1 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Fungal_trans PF04082.13 KUM62026.1 - 2.6e-22 78.9 0.1 1.2e-21 76.7 0.0 2.2 1 1 2 3 3 3 1 Fungal specific transcription factor domain WD40 PF00400.27 KUM62027.1 - 9.7e-25 85.5 6.6 3.8e-09 36.0 0.1 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KUM62027.1 - 3.4e-21 74.8 0.0 9.7e-21 73.4 0.0 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Transglut_core PF01841.14 KUM62028.1 - 2.1e-12 47.2 0.0 4.1e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.7 KUM62028.1 - 0.0025 17.1 0.0 0.008 15.4 0.0 1.8 2 1 0 2 2 2 1 Transglutaminase-like domain Ras PF00071.17 KUM62029.1 - 3.3e-31 107.8 0.2 4.5e-31 107.4 0.2 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KUM62029.1 - 2.9e-20 72.9 0.1 1.1e-19 71.0 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KUM62029.1 - 1.1e-06 28.0 0.1 1.7e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KUM62029.1 - 5.2e-05 22.4 0.2 7.6e-05 21.9 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KUM62029.1 - 0.25 9.9 0.0 0.25 9.9 0.0 2.7 3 1 1 4 4 4 0 G-protein alpha subunit RNR_inhib PF08591.5 KUM62029.1 - 0.28 12.1 4.9 0.66 10.9 3.4 1.6 1 0 0 1 1 1 0 Ribonucleotide reductase inhibitor Ribosomal_L37ae PF01780.14 KUM62030.1 - 1.6e-40 136.8 9.5 1.7e-40 136.7 6.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family A2L_zn_ribbon PF08792.5 KUM62030.1 - 0.0042 16.4 3.3 0.42 10.1 0.1 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 KUM62030.1 - 0.0053 16.5 1.8 0.008 15.9 1.2 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain GCC2_GCC3 PF07699.8 KUM62030.1 - 0.053 13.1 0.2 0.075 12.6 0.2 1.3 1 0 0 1 1 1 0 GCC2 and GCC3 zf-BED PF02892.10 KUM62030.1 - 0.055 13.2 3.5 1.7 8.4 0.1 2.3 1 1 1 2 2 2 0 BED zinc finger Tnp_zf-ribbon_2 PF13842.1 KUM62030.1 - 0.26 11.7 2.6 0.6 10.5 1.8 1.7 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon NOB1_Zn_bind PF08772.6 KUM62030.1 - 0.26 11.1 2.9 0.3 10.9 0.2 2.0 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Rep_fac-A_C PF08646.5 KUM62030.1 - 0.37 10.4 2.4 0.62 9.7 1.6 1.5 1 1 0 1 1 1 0 Replication factor-A C terminal domain zf-C2H2 PF00096.21 KUM62030.1 - 0.57 10.6 3.1 17 6.0 0.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KUM62030.1 - 1.6 9.2 4.5 16 6.0 0.2 2.3 1 1 1 2 2 2 0 Zinc-finger double domain Saccharop_dh PF03435.13 KUM62031.1 - 8.4e-22 77.6 0.0 1.6e-21 76.7 0.0 1.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase Abhydrolase_6 PF12697.2 KUM62032.1 - 6e-20 72.1 0.1 7.9e-11 42.2 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM62032.1 - 1.7e-10 40.8 0.0 7.4e-10 38.7 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KUM62032.1 - 8.9e-06 25.5 0.0 0.022 14.5 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KUM62032.1 - 0.0018 18.0 0.0 0.0034 17.2 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 KUM62032.1 - 0.025 14.4 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein PHF5 PF03660.9 KUM62033.1 - 4.5e-52 174.6 9.3 5.1e-52 174.4 6.4 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 KUM62033.1 - 0.9 9.4 15.4 8.3 6.3 1.6 2.7 1 1 1 2 2 2 0 Double zinc ribbon Prok-RING_1 PF14446.1 KUM62033.1 - 1.4 8.7 15.7 2.9 7.6 0.5 3.0 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PolC_DP2 PF03833.8 KUM62033.1 - 4.6 4.7 5.8 4.7 4.7 4.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 PHD PF00628.24 KUM62033.1 - 8.5 6.1 15.7 0.22 11.2 4.6 2.5 1 1 1 2 2 2 0 PHD-finger Pinin_SDK_memA PF04696.8 KUM62034.1 - 3.1e-27 94.7 10.1 3.1e-27 94.7 7.0 2.4 3 0 0 3 3 3 1 pinin/SDK/memA/ protein conserved region Cofilin_ADF PF00241.15 KUM62035.1 - 1.8e-15 56.9 0.0 2.9e-07 30.4 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DUF2207 PF09972.4 KUM62036.1 - 0.005 15.4 0.1 0.0062 15.1 0.1 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) BRF1 PF07741.8 KUM62036.1 - 0.0063 16.7 5.8 0.0066 16.6 4.0 1.2 1 0 0 1 1 1 1 Brf1-like TBP-binding domain Rtf2 PF04641.7 KUM62036.1 - 0.035 13.3 5.5 0.033 13.3 3.8 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Cnd1_N PF12922.2 KUM62036.1 - 0.058 13.0 2.8 0.074 12.6 2.0 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term DUF3984 PF13136.1 KUM62036.1 - 0.092 11.9 1.2 0.11 11.6 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) GAGA_bind PF06217.7 KUM62036.1 - 0.14 12.0 5.1 0.14 12.0 3.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family GST_C_3 PF14497.1 KUM62036.1 - 0.41 11.1 2.0 0.58 10.6 1.4 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain BLVR PF06375.6 KUM62036.1 - 1.2 8.9 22.5 1.5 8.6 15.6 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) YqhR PF11085.3 KUM62036.1 - 2.5 7.5 4.8 0.68 9.4 0.5 2.0 1 1 1 2 2 2 0 Conserved membrane protein YqhR SR-25 PF10500.4 KUM62036.1 - 3.4 7.0 23.3 4.1 6.8 16.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TAF1D PF15333.1 KUM62036.1 - 5.2 6.7 14.7 6.1 6.5 10.2 1.1 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D DUF1168 PF06658.7 KUM62036.1 - 5.5 6.5 24.7 6.7 6.2 17.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) RR_TM4-6 PF06459.7 KUM62036.1 - 9 6.0 7.3 11 5.8 5.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PHD PF00628.24 KUM62037.1 - 8.7e-11 41.3 13.4 1.1e-10 41.0 3.3 2.6 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 KUM62037.1 - 1.6e-08 34.2 6.0 1.6e-08 34.2 4.2 3.2 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KUM62037.1 - 1.4e-06 28.2 1.1 1.4e-06 28.2 0.7 3.3 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KUM62037.1 - 2.2e-06 27.2 1.2 2.2e-06 27.2 0.8 2.6 2 2 1 3 3 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KUM62037.1 - 2.9e-06 26.8 1.0 2.9e-06 26.8 0.7 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KUM62037.1 - 6.3e-06 26.2 2.1 6.3e-06 26.2 1.4 2.1 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KUM62037.1 - 1.1e-05 24.9 4.9 1.1e-05 24.9 3.4 3.1 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 KUM62037.1 - 7.1e-05 22.2 2.9 0.00062 19.2 0.2 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 PHD_2 PF13831.1 KUM62037.1 - 0.0002 20.5 1.9 0.00051 19.3 1.3 1.7 1 0 0 1 1 1 1 PHD-finger zf-Apc11 PF12861.2 KUM62037.1 - 0.004 16.9 0.1 0.004 16.9 0.1 1.7 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2HC_2 PF13913.1 KUM62037.1 - 0.015 14.9 2.2 0.18 11.5 0.2 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-RING_UBOX PF13445.1 KUM62037.1 - 0.055 13.1 4.9 0.078 12.7 0.5 3.0 2 1 1 3 3 3 0 RING-type zinc-finger zf-RING_4 PF14570.1 KUM62037.1 - 2.2 7.9 5.6 0.32 10.6 0.3 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.1 KUM62037.1 - 2.5 7.9 8.4 0.3 10.8 0.7 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 DZR PF12773.2 KUM62037.1 - 2.8 7.8 8.2 5.2e+02 0.5 5.7 3.1 1 1 0 1 1 1 0 Double zinc ribbon TRAM_LAG1_CLN8 PF03798.11 KUM62040.1 - 1.4e-35 122.6 19.1 1.4e-35 122.6 13.3 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KUM62040.1 - 3.3e-23 80.9 0.4 6.8e-23 79.9 0.0 1.8 2 0 0 2 2 2 1 TRAM1-like protein Sulfatase PF00884.18 KUM62042.1 - 2e-24 86.3 1.3 4e-24 85.3 0.9 1.5 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KUM62042.1 - 7.6e-07 28.7 0.7 1.4e-06 27.9 0.5 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Neurensin PF14927.1 KUM62042.1 - 0.22 10.8 1.2 4.9 6.5 0.0 2.7 3 0 0 3 3 3 0 Neurensin Shisa PF13908.1 KUM62042.1 - 0.63 10.1 2.2 2.1 8.5 0.9 2.1 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Sugar_tr PF00083.19 KUM62043.1 - 6.5e-107 357.8 21.7 8.6e-107 357.5 15.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM62043.1 - 1.2e-24 86.6 31.7 7.6e-23 80.7 13.5 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KUM62043.1 - 0.0011 17.4 29.6 0.0039 15.6 5.0 3.5 3 1 0 3 3 3 2 MFS/sugar transport protein Polysacc_deac_1 PF01522.16 KUM62044.1 - 5.5e-32 109.9 0.0 1.1e-31 109.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 KUM62044.1 - 0.0096 15.8 15.6 0.0096 15.8 10.8 3.0 2 1 1 3 3 3 1 Chitin recognition protein Glyco_hydro_57 PF03065.10 KUM62044.1 - 0.071 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 CENP-T PF15511.1 KUM62046.1 - 0.2 10.8 28.7 0.21 10.7 19.9 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF4407 PF14362.1 KUM62046.1 - 6.9 5.5 9.8 7 5.5 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HEAT_2 PF13646.1 KUM62047.1 - 2.1e-05 24.6 0.3 0.0002 21.5 0.0 2.5 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.17 KUM62047.1 - 4.5e-05 23.1 1.2 0.068 13.2 0.0 4.3 5 0 0 5 5 5 1 HEAT repeat Cnd3 PF12719.2 KUM62047.1 - 0.0047 15.9 0.2 0.014 14.3 0.0 1.9 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Vac14_Fab1_bd PF12755.2 KUM62047.1 - 0.0092 16.3 0.0 0.028 14.8 0.0 1.8 1 0 0 1 1 1 1 Vacuolar 14 Fab1-binding region UME PF08064.8 KUM62047.1 - 0.0093 15.8 0.2 4.9 7.1 0.0 2.8 3 0 0 3 3 3 2 UME (NUC010) domain DUF4072 PF13284.1 KUM62047.1 - 0.012 15.7 0.0 0.035 14.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4072) Adaptin_N PF01602.15 KUM62047.1 - 0.014 13.7 0.3 0.6 8.3 0.0 2.6 2 1 1 3 3 3 0 Adaptin N terminal region V-ATPase_H_N PF03224.9 KUM62047.1 - 0.046 12.8 0.4 0.063 12.3 0.3 1.4 1 1 0 1 1 1 0 V-ATPase subunit H DRIM PF07539.7 KUM62047.1 - 0.05 13.0 0.0 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 Down-regulated in metastasis HEAT_EZ PF13513.1 KUM62047.1 - 0.34 11.4 3.5 8.3 7.0 0.0 3.9 4 1 1 5 5 5 0 HEAT-like repeat His_biosynth PF00977.16 KUM62048.1 - 4e-31 108.0 0.0 4.8e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein DUF4602 PF15375.1 KUM62049.1 - 0.00025 21.1 11.6 0.00025 21.1 8.1 2.1 2 2 0 2 2 2 1 Domain of unknown function (DUF4602) BNIP2 PF12496.3 KUM62049.1 - 8.8 6.5 11.0 1.6 8.8 4.6 1.9 1 1 1 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DUF2310 PF10071.4 KUM62050.1 - 0.015 14.2 0.1 0.02 13.8 0.0 1.1 1 0 0 1 1 1 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) Daxx PF03344.10 KUM62050.1 - 5.2 5.4 9.9 6.1 5.1 6.8 1.0 1 0 0 1 1 1 0 Daxx Family CoA_binding PF02629.14 KUM62051.1 - 1.8e-25 89.2 2.2 2.2e-24 85.7 0.3 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 KUM62051.1 - 6.2e-22 77.8 0.1 1e-21 77.1 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KUM62051.1 - 1.3e-06 28.1 0.0 2.6e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 KUM62051.1 - 0.015 15.5 0.1 0.035 14.2 0.0 1.7 2 0 0 2 2 2 0 CoA binding domain Radical_SAM PF04055.16 KUM62052.1 - 3.7e-18 66.2 0.1 1.5e-17 64.2 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 KUM62052.1 - 2.8e-12 46.5 0.1 7.8e-12 45.0 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KUM62052.1 - 0.04 14.0 0.1 0.12 12.5 0.1 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Yip1 PF04893.12 KUM62053.1 - 0.018 14.5 0.3 0.025 14.0 0.2 1.2 1 0 0 1 1 1 0 Yip1 domain Col_cuticle_N PF01484.12 KUM62053.1 - 4.7 6.9 7.0 0.59 9.8 0.2 2.7 3 0 0 3 3 3 0 Nematode cuticle collagen N-terminal domain Isochorismatase PF00857.15 KUM62054.1 - 4.9e-19 68.9 0.0 1.2e-18 67.6 0.0 1.6 1 1 0 1 1 1 1 Isochorismatase family NPP PF08384.5 KUM62054.1 - 0.058 13.0 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 Pro-opiomelanocortin, N-terminal region NAD_binding_4 PF07993.7 KUM62056.1 - 1.5e-55 187.7 0.0 2.1e-55 187.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KUM62056.1 - 2.8e-26 91.8 0.0 5.8e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 KUM62056.1 - 2.5e-10 40.4 0.1 5e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 KUM62056.1 - 1e-08 34.9 0.0 1.9e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 KUM62056.1 - 1.1e-06 29.4 0.0 2.5e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 KUM62056.1 - 4.3e-05 22.3 0.0 6.8e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KUM62056.1 - 0.0068 15.3 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Myb_DNA-binding PF00249.26 KUM62057.1 - 0.035 14.1 0.0 0.094 12.7 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain Phage_tail_L PF05100.7 KUM62057.1 - 0.12 11.4 0.8 3.7 6.6 0.2 2.2 2 0 0 2 2 2 0 Phage minor tail protein L SWIRM PF04433.12 KUM62058.1 - 5.5e-34 116.1 0.0 1.5e-33 114.8 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 KUM62058.1 - 3.7e-06 26.8 0.0 7.7e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KUM62058.1 - 1.2e-05 25.3 0.0 3.1e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 KUM62058.1 - 0.032 13.7 5.1 0.26 10.8 3.5 2.1 1 1 0 1 1 1 0 Zinc finger, ZZ type DUF4192 PF13830.1 KUM62058.1 - 0.047 13.3 7.9 0.11 12.1 5.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) DUF883 PF05957.8 KUM62058.1 - 0.092 13.1 9.3 0.13 12.6 2.8 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) V_ATPase_I PF01496.14 KUM62058.1 - 0.2 9.4 2.0 0.29 8.9 1.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ABC_tran PF00005.22 KUM62059.1 - 5e-46 156.4 0.1 1.9e-23 83.3 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KUM62059.1 - 3.8e-15 56.6 0.3 0.0019 18.1 0.1 4.3 3 1 1 4 4 4 3 AAA domain SMC_N PF02463.14 KUM62059.1 - 5.3e-13 48.7 0.1 0.00016 20.9 0.0 4.0 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KUM62059.1 - 2.2e-09 36.6 0.1 0.0013 18.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KUM62059.1 - 4.1e-09 37.0 0.1 0.0019 18.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 KUM62059.1 - 1e-07 32.0 0.0 0.0093 15.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KUM62059.1 - 4e-07 30.8 0.1 0.035 14.9 0.0 3.1 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 KUM62059.1 - 7.2e-06 25.9 0.1 0.022 14.7 0.0 3.4 3 0 0 3 3 3 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 KUM62059.1 - 7.5e-06 25.4 0.0 0.094 12.1 0.0 2.9 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 KUM62059.1 - 9.3e-06 25.8 0.0 0.013 15.6 0.0 3.1 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 KUM62059.1 - 1.1e-05 24.6 0.0 0.0087 15.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 KUM62059.1 - 1.3e-05 24.9 0.0 0.041 13.7 0.0 3.0 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Miro PF08477.8 KUM62059.1 - 1.7e-05 25.2 0.0 0.023 15.1 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 KUM62059.1 - 2.2e-05 24.7 0.3 0.51 10.6 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.1 KUM62059.1 - 3.9e-05 22.8 2.8 0.75 8.7 0.0 3.8 2 2 0 3 3 3 1 AAA ATPase domain NACHT PF05729.7 KUM62059.1 - 4.7e-05 23.1 0.0 0.033 13.8 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_10 PF12846.2 KUM62059.1 - 4.8e-05 22.9 0.0 0.33 10.3 0.0 3.1 3 0 0 3 3 3 2 AAA-like domain AAA_16 PF13191.1 KUM62059.1 - 5.2e-05 23.3 0.0 1 9.3 0.0 3.7 3 0 0 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 KUM62059.1 - 6.6e-05 22.8 0.0 0.21 11.5 0.0 3.6 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.17 KUM62059.1 - 8.6e-05 22.6 0.0 0.42 10.7 0.0 2.8 2 0 0 2 2 2 2 RNA helicase DUF87 PF01935.12 KUM62059.1 - 9.2e-05 22.3 0.4 0.058 13.2 0.1 3.1 3 0 0 3 3 2 1 Domain of unknown function DUF87 AAA_33 PF13671.1 KUM62059.1 - 0.00012 21.9 0.0 0.49 10.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain HEAT_2 PF13646.1 KUM62059.1 - 0.00013 22.1 2.1 0.77 10.0 0.0 3.2 2 1 2 4 4 3 3 HEAT repeats cobW PF02492.14 KUM62059.1 - 0.00017 21.0 0.8 0.13 11.6 0.0 3.6 4 0 0 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 KUM62059.1 - 0.00022 21.3 0.0 0.16 12.1 0.0 4.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 KUM62059.1 - 0.00029 20.7 0.0 0.0026 17.5 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_13 PF13166.1 KUM62059.1 - 0.00034 19.2 1.1 0.42 9.0 0.0 3.4 4 0 0 4 4 4 2 AAA domain MobB PF03205.9 KUM62059.1 - 0.00042 20.0 0.2 0.85 9.3 0.0 3.1 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KUM62059.1 - 0.00082 18.8 0.0 1.3 8.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KUM62059.1 - 0.0016 18.0 0.0 1.8 8.1 0.0 3.5 4 0 0 4 4 3 1 AAA domain HEAT_EZ PF13513.1 KUM62059.1 - 0.0018 18.6 1.3 6.7 7.3 0.0 5.0 4 1 1 5 5 3 0 HEAT-like repeat ArgK PF03308.11 KUM62059.1 - 0.0018 17.0 0.1 1 8.0 0.0 2.4 2 0 0 2 2 2 2 ArgK protein Arch_ATPase PF01637.13 KUM62059.1 - 0.002 17.8 0.0 0.094 12.3 0.0 2.7 2 0 0 2 2 2 1 Archaeal ATPase ATP-synt_ab PF00006.20 KUM62059.1 - 0.0039 16.7 0.0 0.64 9.4 0.0 2.9 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 KUM62059.1 - 0.0046 16.4 0.4 0.13 11.6 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_19 PF13245.1 KUM62059.1 - 0.0081 15.8 0.1 6.1 6.6 0.0 3.5 3 0 0 3 3 2 0 Part of AAA domain ATP_bind_1 PF03029.12 KUM62059.1 - 0.025 14.1 0.0 6.3 6.2 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.17 KUM62059.1 - 0.027 13.3 0.0 0.25 10.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Septin PF00735.13 KUM62059.1 - 0.057 12.4 3.1 1.4 7.8 0.0 3.3 4 0 0 4 4 3 0 Septin G-alpha PF00503.15 KUM62059.1 - 0.059 12.0 0.0 1.7 7.2 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit Arf PF00025.16 KUM62059.1 - 0.059 12.5 0.1 5.9 6.1 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF1981 PF09324.5 KUM62059.1 - 0.11 12.0 0.1 0.37 10.3 0.0 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF1981) ResIII PF04851.10 KUM62060.1 - 1.6e-22 80.2 0.0 3e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KUM62060.1 - 7.6e-12 44.9 0.0 1.8e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KUM62060.1 - 7.5e-11 41.8 0.0 1.4e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 KUM62060.1 - 0.0011 18.0 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.18 KUM62060.1 - 0.032 13.0 0.0 0.056 12.2 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain Gly_transf_sug PF04488.10 KUM62061.1 - 1.3e-10 41.5 0.8 5.1e-10 39.6 0.6 1.9 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KUM62061.1 - 0.003 16.1 0.0 0.0078 14.7 0.0 1.6 2 0 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain SnoaL_4 PF13577.1 KUM62062.1 - 1.6e-17 63.6 0.0 1.8e-17 63.4 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain MFS_1 PF07690.11 KUM62064.1 - 8.3e-24 83.9 52.3 8.3e-24 83.9 36.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily PGAP1 PF07819.8 KUM62066.1 - 3.8e-83 278.4 0.0 6e-83 277.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KUM62066.1 - 4.8e-10 39.3 0.1 9.1e-10 38.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KUM62066.1 - 7.5e-07 29.2 0.3 1.3e-06 28.4 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM62066.1 - 0.0057 16.2 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 KUM62066.1 - 0.0078 15.6 0.0 0.032 13.6 0.0 1.8 2 0 0 2 2 2 1 Putative esterase LCAT PF02450.10 KUM62066.1 - 0.018 14.0 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 KUM62066.1 - 0.043 13.0 0.0 0.076 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Methyltransf_10 PF05971.7 KUM62067.1 - 4.5e-53 180.3 0.4 9.3e-31 107.0 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF890) MTS PF05175.9 KUM62067.1 - 0.00017 21.0 0.0 0.0004 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KUM62067.1 - 0.0033 17.4 0.0 0.01 15.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 KUM62067.1 - 0.13 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.5 KUM62067.1 - 0.15 11.6 0.0 0.36 10.3 0.0 1.6 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase MFS_1 PF07690.11 KUM62068.1 - 1.2e-41 142.5 39.8 2.9e-38 131.5 14.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM62068.1 - 2.3e-08 33.0 10.2 2.3e-08 33.0 7.0 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter TatC PF00902.13 KUM62068.1 - 2.7 7.3 15.8 0.65 9.3 1.0 3.6 4 0 0 4 4 4 0 Sec-independent protein translocase protein (TatC) Cellulase PF00150.13 KUM62069.1 - 1.7e-31 109.4 2.6 7.7e-31 107.3 0.9 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) TPR_11 PF13414.1 KUM62070.1 - 8.6e-10 38.1 2.5 1e-06 28.2 0.0 5.1 5 1 2 7 7 7 2 TPR repeat TPR_1 PF00515.23 KUM62070.1 - 0.0015 18.0 1.3 0.21 11.2 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 KUM62070.1 - 0.0086 15.9 11.6 0.017 15.0 0.0 5.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 KUM62070.1 - 0.016 15.3 0.0 1.8 8.9 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KUM62070.1 - 0.03 14.1 0.4 46 4.1 0.0 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KUM62070.1 - 0.042 13.6 0.6 2 8.3 0.0 3.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 KUM62070.1 - 0.15 12.0 9.0 13 5.8 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 KUM62070.1 - 0.34 11.6 6.1 0.43 11.3 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KUM62070.1 - 2.7 8.3 8.9 3.3 8.0 0.2 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Complex1_LYR_1 PF13232.1 KUM62071.1 - 1e-05 25.6 0.2 2.4e-05 24.4 0.2 1.6 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KUM62071.1 - 4e-05 23.3 0.8 9.1e-05 22.1 0.5 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Ank_4 PF13637.1 KUM62072.1 - 3.1e-13 49.8 0.5 4.5e-09 36.5 0.1 3.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM62072.1 - 9.9e-07 28.8 1.5 0.00021 21.4 0.1 3.3 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KUM62072.1 - 3.2e-06 27.3 0.1 0.0081 16.4 0.1 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KUM62072.1 - 0.00033 20.5 1.2 0.062 13.5 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeat KilA-N PF04383.8 KUM62072.1 - 0.0051 16.4 0.3 0.028 14.0 0.2 2.1 1 1 0 1 1 1 1 KilA-N domain YkyA PF10368.4 KUM62072.1 - 0.096 12.0 1.5 0.17 11.1 1.0 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Baculo_PEP_C PF04513.7 KUM62072.1 - 0.12 12.1 0.0 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ank PF00023.25 KUM62072.1 - 0.19 11.6 3.8 0.75 9.7 0.1 3.4 3 0 0 3 3 3 0 Ankyrin repeat Sugar_tr PF00083.19 KUM62073.1 - 2.2e-36 125.4 17.6 3.7e-36 124.6 12.2 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM62073.1 - 6.8e-29 100.6 27.5 8.1e-29 100.4 18.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Rick_17kDa_Anti PF05433.10 KUM62074.1 - 8.7e-05 22.0 12.1 8.7e-05 22.0 8.4 1.9 2 0 0 2 2 2 1 Glycine zipper 2TM domain BLVR PF06375.6 KUM62074.1 - 0.013 15.3 11.3 0.019 14.8 7.8 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) SR-25 PF10500.4 KUM62074.1 - 0.023 14.1 16.5 0.033 13.6 11.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3824 PF12868.2 KUM62074.1 - 0.04 14.8 2.4 0.04 14.8 1.7 3.2 2 1 0 2 2 1 0 Domain of unknwon function (DUF3824) MarC PF01914.12 KUM62074.1 - 0.063 12.3 0.2 0.085 11.9 0.1 1.1 1 0 0 1 1 1 0 MarC family integral membrane protein SNARE_assoc PF09335.6 KUM62074.1 - 0.081 13.1 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 SNARE associated Golgi protein PAT1 PF09770.4 KUM62074.1 - 0.091 10.9 21.7 0.12 10.6 15.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF755 PF05501.6 KUM62074.1 - 0.095 12.7 23.0 0.17 11.9 15.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) LysE PF01810.13 KUM62074.1 - 0.12 11.6 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 LysE type translocator TerC PF03741.11 KUM62074.1 - 0.18 11.2 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 Integral membrane protein TerC family Gly-zipper_OmpA PF13436.1 KUM62074.1 - 0.23 11.1 6.6 0.58 9.8 4.6 1.7 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DUF533 PF04391.7 KUM62074.1 - 4 6.7 13.7 0.043 13.1 3.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF533) TFIIF_alpha PF05793.7 KUM62074.1 - 4.6 5.5 16.1 5.7 5.1 11.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) His_Phos_2 PF00328.17 KUM62075.1 - 1.6e-31 109.8 0.0 5.1e-31 108.2 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Tcp11 PF05794.8 KUM62077.1 - 3.4e-50 171.0 0.0 7.6e-50 169.8 0.0 1.5 1 0 0 1 1 1 1 T-complex protein 11 Sugar_tr PF00083.19 KUM62078.1 - 0.01 14.4 0.0 0.012 14.2 0.0 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter Peptidase_S10 PF00450.17 KUM62079.1 - 5.5e-111 371.6 0.0 6.8e-111 371.3 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KUM62079.1 - 0.0028 17.5 0.0 0.028 14.2 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2530 PF10745.4 KUM62079.1 - 0.093 12.7 0.3 0.17 11.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) MLANA PF14991.1 KUM62079.1 - 0.12 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A DUF2522 PF10747.4 KUM62079.1 - 0.12 12.4 0.2 0.39 10.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2522) WD40 PF00400.27 KUM62080.1 - 8.7e-53 174.4 16.2 4.1e-11 42.3 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KUM62080.1 - 0.0035 16.8 0.0 6.4 6.3 0.0 4.1 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Endosulfine PF04667.12 KUM62081.1 - 8.1e-22 76.9 0.0 1.2e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region RNA_Me_trans PF04252.8 KUM62082.1 - 2.9e-47 160.6 0.0 3.7e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase bPH_5 PF10882.3 KUM62082.1 - 0.017 14.8 0.0 3.1 7.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial PH domain UPF0160 PF03690.8 KUM62083.1 - 1.5e-118 395.8 0.0 1.7e-118 395.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) ICE2 PF08426.5 KUM62084.1 - 1.5e-141 471.7 10.7 1.8e-141 471.5 7.4 1.0 1 0 0 1 1 1 1 ICE2 zinc_ribbon_6 PF14599.1 KUM62085.1 - 3.8e-25 87.4 0.3 5.7e-25 86.8 0.2 1.3 1 0 0 1 1 1 1 Zinc-ribbon Zn_ribbon_recom PF13408.1 KUM62085.1 - 0.097 12.9 1.2 0.19 11.9 0.8 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain CENP-T PF15511.1 KUM62085.1 - 0.39 9.9 14.1 0.031 13.5 1.7 2.0 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T DNA_pol_phi PF04931.8 KUM62085.1 - 0.62 7.7 8.1 0.85 7.3 5.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.7 KUM62085.1 - 7.8 5.6 7.0 47 3.0 3.8 2.0 2 0 0 2 2 2 0 NOA36 protein zf-CHY PF05495.7 KUM62086.1 - 1.2e-16 60.5 22.9 1.2e-16 60.5 15.9 2.0 2 0 0 2 2 2 1 CHY zinc finger DUF3336 PF11815.3 KUM62087.1 - 1.2e-38 131.8 0.1 4.7e-38 129.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KUM62087.1 - 4.4e-16 59.4 0.4 1e-15 58.2 0.1 1.8 2 0 0 2 2 2 1 Patatin-like phospholipase TAFH PF07531.9 KUM62087.1 - 0.01 15.4 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 NHR1 homology to TAF ETC_C1_NDUFA4 PF04800.7 KUM62087.1 - 0.048 13.5 1.6 0.098 12.5 1.1 1.4 1 0 0 1 1 1 0 ETC complex I subunit conserved region Ribosomal_L6 PF00347.18 KUM62088.1 - 5.5e-21 74.8 3.1 3e-09 37.2 0.8 2.5 2 0 0 2 2 2 2 Ribosomal protein L6 Glutaredoxin PF00462.19 KUM62088.1 - 1.2e-05 25.1 0.0 4.1e-05 23.4 0.0 2.0 1 0 0 1 1 1 1 Glutaredoxin Abhydrolase_6 PF12697.2 KUM62089.1 - 5e-19 69.0 0.2 6.2e-18 65.5 0.1 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM62089.1 - 1.1e-07 31.6 0.0 3e-06 27.0 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM62089.1 - 3.6e-06 26.7 0.0 8.3e-06 25.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 KUM62089.1 - 0.19 10.9 0.0 0.41 9.8 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF814 PF05670.8 KUM62090.1 - 5.8e-18 64.5 0.1 1.5e-17 63.2 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF814) TBCC PF07986.7 KUM62090.1 - 0.019 14.3 0.0 0.23 10.8 0.0 2.3 2 1 1 3 3 3 0 Tubulin binding cofactor C Paramyxo_ncap PF00973.14 KUM62090.1 - 2.6 6.6 6.5 3.2 6.3 4.5 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF372 PF04036.7 KUM62091.1 - 0.026 14.0 0.2 0.65 9.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF372) PXA PF02194.10 KUM62093.1 - 1.2e-51 174.9 0.2 1.2e-51 174.9 0.1 2.9 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.7 KUM62093.1 - 2.2e-28 98.6 0.2 5e-27 94.2 0.0 3.0 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 KUM62093.1 - 8e-22 77.1 0.7 1.8e-21 76.0 0.5 1.6 1 0 0 1 1 1 1 PX domain RGS PF00615.14 KUM62093.1 - 5e-11 42.7 0.0 1.7e-10 41.0 0.0 2.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF1670 PF07900.6 KUM62093.1 - 0.098 11.8 0.9 1.3 8.2 0.0 3.0 5 0 0 5 5 5 0 Protein of unknown function (DUF1670) WD40 PF00400.27 KUM62094.1 - 7.5e-29 98.5 1.7 6.9e-07 28.9 0.1 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat FliO PF04347.8 KUM62094.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Flagellar biosynthesis protein, FliO RXT2_N PF08595.6 KUM62096.1 - 3.1e-40 137.4 0.0 3.1e-40 137.4 0.0 2.0 2 0 0 2 2 2 1 RXT2-like, N-terminal Gryzun PF07919.7 KUM62097.1 - 1e-148 496.1 0.3 1.3e-148 495.7 0.2 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 KUM62097.1 - 6.3e-97 323.8 1.6 2.3e-87 292.5 2.8 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.2 KUM62097.1 - 0.079 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking PEMT PF04191.8 KUM62098.1 - 3e-32 110.8 3.0 3e-32 110.8 2.1 1.6 2 0 0 2 2 2 1 Phospholipid methyltransferase YrhK PF14145.1 KUM62098.1 - 0.0016 18.0 1.3 0.003 17.2 0.3 1.9 2 0 0 2 2 2 1 YrhK-like protein DUF1223 PF06764.6 KUM62098.1 - 0.0023 17.7 0.0 0.003 17.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1223) ATP1G1_PLM_MAT8 PF02038.11 KUM62098.1 - 8.8 5.4 6.1 3.4 6.7 1.5 2.1 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Nop14 PF04147.7 KUM62099.1 - 0.25 9.2 4.2 0.28 9.0 2.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDV3 PF15359.1 KUM62099.1 - 0.44 10.6 6.0 0.59 10.2 1.5 2.3 2 1 1 3 3 3 0 Carnitine deficiency-associated protein 3 Yae1_N PF09811.4 KUM62100.1 - 6e-07 28.8 2.7 8.9e-07 28.3 1.9 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal tRNA-synt_1g PF09334.6 KUM62101.1 - 1.2e-138 462.0 0.0 1.6e-138 461.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KUM62101.1 - 6e-10 37.7 0.3 4.1e-05 21.7 0.0 3.9 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KUM62101.1 - 0.008 15.9 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Elongin_A PF06881.6 KUM62101.1 - 0.098 13.0 1.8 0.28 11.5 1.3 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DZR PF12773.2 KUM62101.1 - 0.64 9.8 5.4 2.2 8.1 3.7 1.9 1 1 0 1 1 1 0 Double zinc ribbon Spindle_Spc25 PF08234.7 KUM62102.1 - 2.4e-21 75.4 0.1 6.7e-21 74.0 0.0 1.8 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Filament PF00038.16 KUM62102.1 - 0.0027 17.2 12.6 0.004 16.6 8.8 1.2 1 0 0 1 1 1 1 Intermediate filament protein Pox_LP_H2 PF03356.10 KUM62102.1 - 0.12 12.0 0.1 0.24 11.0 0.0 1.5 2 0 0 2 2 2 0 Viral late protein H2 DUF4140 PF13600.1 KUM62102.1 - 0.36 11.3 4.5 0.63 10.5 3.1 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) TarH PF02203.10 KUM62102.1 - 2 8.2 9.7 1.8 8.3 5.3 1.9 3 0 0 3 3 3 0 Tar ligand binding domain homologue Rrn6 PF10214.4 KUM62103.1 - 5.3e-157 524.1 0.0 6.1e-157 523.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Dppa2_A PF14049.1 KUM62103.1 - 0.043 13.6 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Dppa2/4 conserved region in higher vertebrates DUF222 PF02720.12 KUM62103.1 - 0.095 11.8 0.0 2 7.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF222) HMA PF00403.21 KUM62104.1 - 1.1e-16 60.6 0.9 1.3e-16 60.4 0.6 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF211 PF02680.9 KUM62104.1 - 0.13 12.0 0.1 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 DUF2293 PF10056.4 KUM62105.1 - 2.1e-27 94.9 0.2 2.1e-27 94.9 0.2 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) Septin PF00735.13 KUM62106.1 - 1.1e-109 365.8 0.6 1.3e-109 365.6 0.4 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KUM62106.1 - 6.5e-07 29.3 0.0 1.3e-06 28.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KUM62106.1 - 5.4e-05 22.3 0.0 9.6e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 KUM62106.1 - 0.00044 20.1 0.5 1.1 9.0 0.2 2.5 1 1 1 2 2 2 2 Dynamin family DUF258 PF03193.11 KUM62106.1 - 0.00055 19.1 0.0 0.001 18.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KUM62106.1 - 0.0038 16.6 0.4 0.082 12.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_23 PF13476.1 KUM62106.1 - 0.0056 17.0 0.0 0.011 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KUM62106.1 - 0.016 15.4 0.5 0.021 15.1 0.2 1.6 1 1 0 1 1 1 0 ABC transporter Gtr1_RagA PF04670.7 KUM62106.1 - 0.028 13.5 0.1 0.082 12.0 0.0 1.8 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_10 PF12846.2 KUM62106.1 - 0.029 13.8 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 KUM62106.1 - 0.046 13.8 0.0 0.091 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain Ribosomal_L32p PF01783.18 KUM62108.1 - 1.9e-13 50.3 5.3 2.4e-13 50.0 3.7 1.1 1 0 0 1 1 1 1 Ribosomal L32p protein family DZR PF12773.2 KUM62108.1 - 0.015 15.1 0.5 0.025 14.3 0.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 KUM62108.1 - 1 8.6 7.0 1 8.6 0.4 2.0 1 1 1 2 2 2 0 zinc-ribbon domain UPF0547 PF10571.4 KUM62108.1 - 1.3 8.7 4.2 15 5.3 0.5 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 PhnA_Zn_Ribbon PF08274.7 KUM62108.1 - 2.7 7.8 4.5 30 4.4 3.1 2.1 1 1 0 1 1 1 0 PhnA Zinc-Ribbon WD40 PF00400.27 KUM62109.1 - 1.9e-29 100.4 16.2 4.4e-11 42.2 0.5 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 KUM62109.1 - 1.2e-05 25.1 0.0 0.0015 18.3 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 KUM62109.1 - 0.0051 16.4 0.2 7.6 6.3 0.0 3.5 3 1 0 3 3 3 2 WD40-like Beta Propeller Repeat Nup160 PF11715.3 KUM62109.1 - 0.009 14.1 0.1 0.017 13.2 0.1 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KUM62109.1 - 0.0091 14.3 0.1 1.2 7.3 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Hira PF07569.6 KUM62109.1 - 0.098 11.8 0.1 2.7 7.1 0.0 2.5 2 1 0 2 2 2 0 TUP1-like enhancer of split GRAB PF10375.4 KUM62110.1 - 7.1e-09 34.9 0.2 1.6e-08 33.8 0.2 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Reo_sigmaC PF04582.7 KUM62110.1 - 8.3e-06 25.2 10.7 0.0011 18.2 3.8 2.2 2 0 0 2 2 2 2 Reovirus sigma C capsid protein Filament PF00038.16 KUM62110.1 - 0.0011 18.5 46.8 0.0084 15.6 12.0 3.1 1 1 0 2 2 2 1 Intermediate filament protein Phage_GP20 PF06810.6 KUM62110.1 - 0.0033 16.8 6.8 0.0033 16.8 4.7 4.5 2 1 3 5 5 5 1 Phage minor structural protein GP20 HALZ PF02183.13 KUM62110.1 - 0.033 13.8 0.3 0.033 13.8 0.2 5.2 5 1 0 5 5 5 0 Homeobox associated leucine zipper DUF3584 PF12128.3 KUM62110.1 - 0.16 9.3 45.1 0.28 8.4 31.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.7 KUM62110.1 - 0.23 11.3 15.9 0.57 10.0 0.7 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoO PF09769.4 KUM62110.1 - 0.4 10.3 11.7 1.3 8.7 1.6 3.6 2 2 1 3 3 3 0 Apolipoprotein O DUF4250 PF14056.1 KUM62110.1 - 1.5 8.6 4.7 0.77 9.5 0.3 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4250) Laminin_II PF06009.7 KUM62110.1 - 1.5 8.5 30.6 0.23 11.2 3.4 4.2 1 1 3 4 4 4 0 Laminin Domain II Lebercilin PF15619.1 KUM62110.1 - 4 6.8 56.3 0.051 13.0 11.1 3.5 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Prominin PF05478.6 KUM62110.1 - 4.1 4.8 26.3 0.82 7.1 10.6 2.0 1 1 1 2 2 2 0 Prominin HOOK PF05622.7 KUM62110.1 - 7.5 4.2 54.6 2.7 5.6 17.2 2.5 1 1 0 1 1 1 0 HOOK protein DUF4407 PF14362.1 KUM62110.1 - 8.6 5.2 42.9 0.033 13.1 11.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) CBFD_NFYB_HMF PF00808.18 KUM62111.1 - 4.5e-18 65.0 0.3 8.2e-18 64.2 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KUM62111.1 - 3.8e-05 23.7 0.0 6.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 KUM62111.1 - 0.0087 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated SPOB_ab PF14682.1 KUM62111.1 - 0.061 13.1 0.6 0.084 12.6 0.4 1.2 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal Mrr_N PF14338.1 KUM62111.1 - 0.089 12.8 1.5 0.11 12.5 0.4 1.6 2 0 0 2 2 2 0 Mrr N-terminal domain YolD PF08863.5 KUM62111.1 - 3 7.7 5.1 3.1 7.7 2.8 1.6 2 0 0 2 2 2 0 YolD-like protein Actin PF00022.14 KUM62112.1 - 4.9e-20 71.3 0.0 1.4e-17 63.1 0.0 3.0 2 1 0 2 2 2 2 Actin Kin17_mid PF10357.4 KUM62113.1 - 4.3e-49 165.3 0.8 7.5e-49 164.5 0.6 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 KUM62113.1 - 0.035 14.2 3.6 0.082 13.1 2.5 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type SNAPc_SNAP43 PF09808.4 KUM62113.1 - 0.049 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 zf-C2H2_2 PF12756.2 KUM62113.1 - 0.12 12.4 2.6 0.27 11.3 0.3 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Mucin PF01456.12 KUM62113.1 - 0.16 11.7 7.7 0.27 10.9 5.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein CarbpepA_inh PF02977.10 KUM62113.1 - 0.2 11.2 2.3 0.42 10.2 1.6 1.4 1 0 0 1 1 1 0 Carboxypeptidase A inhibitor Ribosomal_S18 PF01084.15 KUM62113.1 - 0.22 11.4 1.1 0.46 10.3 0.8 1.6 1 0 0 1 1 1 0 Ribosomal protein S18 zf-C2H2_jaz PF12171.3 KUM62113.1 - 4.7 7.4 9.9 0.2 11.8 2.5 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PTR2 PF00854.16 KUM62114.1 - 4.1e-35 121.2 9.3 4.1e-35 121.2 6.5 1.7 1 1 1 2 2 2 1 POT family CcmH PF03918.9 KUM62114.1 - 0.068 12.1 0.3 1.4 7.8 0.1 2.6 2 0 0 2 2 2 0 Cytochrome C biogenesis protein Herpes_US9 PF06072.6 KUM62114.1 - 6.5 6.6 8.9 5 7.0 0.7 3.1 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 MFS_1 PF07690.11 KUM62115.1 - 1.2e-39 136.0 29.4 1.2e-39 136.0 20.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM62115.1 - 2.2e-13 49.6 28.9 4.9e-13 48.4 20.1 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1129 PF06570.6 KUM62115.1 - 9.2 5.5 6.7 12 5.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) SIR2 PF02146.12 KUM62118.1 - 3.2e-50 170.3 0.0 5.2e-50 169.6 0.0 1.4 1 0 0 1 1 1 1 Sir2 family Cupin_2 PF07883.6 KUM62119.1 - 9.8e-08 31.3 0.0 1.6e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Cupin domain MFS_1 PF07690.11 KUM62120.1 - 2.8e-32 111.7 53.2 1.3e-27 96.4 21.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM62120.1 - 6.5e-07 28.2 32.6 3.5e-06 25.8 22.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 KUM62120.1 - 0.0099 15.6 2.3 0.0099 15.6 1.6 2.7 3 0 0 3 3 3 1 MFS_1 like family Glyco_hydro_32C PF08244.7 KUM62123.1 - 2e-19 69.7 0.2 3.7e-19 68.8 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.15 KUM62123.1 - 3e-13 49.8 0.0 5.3e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain zf-CCCH PF00642.19 KUM62124.1 - 8.1e-09 34.9 17.3 2.8e-07 30.0 1.5 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 KUM62124.1 - 0.00056 19.7 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KUM62124.1 - 0.0079 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SCRG1 PF15224.1 KUM62124.1 - 1.5 8.6 5.8 0.82 9.5 0.4 2.3 2 0 0 2 2 2 0 Scrapie-responsive protein 1 SMC_Nse1 PF07574.8 KUM62125.1 - 1.2e-33 116.4 0.0 1.6e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 KUM62125.1 - 7.9e-13 48.1 10.1 1.3e-12 47.4 7.0 1.4 1 0 0 1 1 1 1 RING-like domain zf-Apc11 PF12861.2 KUM62125.1 - 0.0011 18.7 2.4 0.0019 17.9 1.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KUM62125.1 - 0.0016 18.2 7.3 0.0026 17.5 5.1 1.4 1 0 0 1 1 1 1 Ring finger domain C1_1 PF00130.17 KUM62125.1 - 0.0089 15.7 3.6 0.0089 15.7 2.5 2.1 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-rbx1 PF12678.2 KUM62125.1 - 0.045 13.8 2.7 0.083 13.0 1.9 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger FYDLN_acid PF09538.5 KUM62125.1 - 0.44 11.1 3.4 0.17 12.4 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-C3HC4 PF00097.20 KUM62125.1 - 0.76 9.4 8.0 1.4 8.5 5.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KUM62125.1 - 0.91 9.5 5.8 2.9 7.9 4.0 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Glyco_hydro_65m PF03632.10 KUM62126.1 - 9.9e-84 281.1 4.0 5e-83 278.8 2.8 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 KUM62126.1 - 2.1e-49 168.1 0.1 4.3e-49 167.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.10 KUM62126.1 - 2e-07 30.9 0.1 4.2e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain 3Beta_HSD PF01073.14 KUM62127.1 - 2.9e-08 32.7 0.0 7.6e-08 31.3 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KUM62127.1 - 1.3e-07 31.3 0.0 4e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KUM62127.1 - 1.3e-05 24.2 0.0 1.8e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KUM62127.1 - 0.00025 21.1 0.0 0.00064 19.7 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KUM62128.1 - 1.1e-33 116.5 1.3 1.5e-33 116.1 0.4 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KUM62128.1 - 5.3e-15 55.5 1.1 9.4e-15 54.7 0.5 1.6 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 KUM62128.1 - 9.3e-12 45.2 0.0 1.2e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KUM62128.1 - 1.3e-05 25.2 0.2 2.2e-05 24.5 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KUM62128.1 - 0.00082 18.8 0.1 0.0038 16.7 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KUM62128.1 - 0.0043 16.3 0.4 0.009 15.2 0.2 1.6 2 0 0 2 2 2 1 NmrA-like family Shikimate_DH PF01488.15 KUM62128.1 - 0.023 14.7 0.0 0.062 13.4 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 KUM62128.1 - 0.099 13.0 0.1 0.29 11.5 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 KUM62130.1 - 9.4e-17 61.4 0.0 1.2e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM62130.1 - 4.1e-12 46.1 0.0 5.2e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KUM62130.1 - 7.7e-07 29.1 0.0 9.8e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sugar_tr PF00083.19 KUM62131.1 - 1.2e-103 347.1 21.5 1.5e-103 346.8 14.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM62131.1 - 1.8e-20 72.9 34.9 5.2e-17 61.6 3.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KUM62131.1 - 0.022 12.8 3.9 0.031 12.3 1.5 2.1 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF3917 PF13055.1 KUM62131.1 - 0.025 14.8 0.3 0.13 12.5 0.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3917) p450 PF00067.17 KUM62132.1 - 3.5e-61 207.1 0.0 4.7e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FANCI_S1 PF14675.1 KUM62132.1 - 0.021 14.1 0.0 0.047 13.0 0.0 1.5 1 0 0 1 1 1 0 FANCI solenoid 1 Peptidase_S28 PF05577.7 KUM62133.1 - 6.9e-56 189.6 6.0 2.1e-55 188.0 3.8 1.9 2 1 0 2 2 2 1 Serine carboxypeptidase S28 DAO PF01266.19 KUM62134.1 - 4e-36 124.6 0.2 6.8e-36 123.9 0.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KUM62134.1 - 0.0018 18.6 0.1 0.27 11.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM62134.1 - 0.014 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Mqo PF06039.10 KUM62134.1 - 0.024 12.8 0.0 0.059 11.5 0.0 1.6 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.9 KUM62134.1 - 0.042 13.7 0.0 2.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3354 PF11834.3 KUM62134.1 - 0.043 13.4 0.4 0.19 11.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3354) Catalase PF00199.14 KUM62135.1 - 1.7e-160 533.9 1.0 2.5e-160 533.3 0.7 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KUM62135.1 - 1.8e-18 66.1 0.1 3.8e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Acetyltransf_1 PF00583.19 KUM62136.1 - 3.6e-08 33.3 0.0 5.2e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KUM62136.1 - 5.4e-07 29.6 0.0 9e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KUM62136.1 - 0.00045 20.3 0.0 0.0016 18.5 0.0 1.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KUM62136.1 - 0.0024 17.7 0.0 0.15 11.8 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Na_Ca_ex PF01699.19 KUM62137.1 - 7.4e-26 90.4 31.2 3.5e-15 55.8 7.5 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein LLGL PF08366.8 KUM62137.1 - 0.063 13.1 0.1 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 LLGL2 DUF3955 PF13127.1 KUM62137.1 - 3.7 7.1 10.7 0.16 11.4 1.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3955) Fungal_trans_2 PF11951.3 KUM62138.1 - 2.8e-19 69.0 6.1 1e-18 67.1 4.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM62138.1 - 3.2e-05 23.7 14.4 3.2e-05 23.7 10.0 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EHN PF06441.7 KUM62139.1 - 4.3e-34 116.7 0.0 7.2e-34 116.0 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KUM62139.1 - 8.3e-10 38.9 0.0 1.2e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM62139.1 - 3.7e-06 26.6 0.0 6.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cupin_2 PF07883.6 KUM62140.1 - 2.5e-05 23.6 0.1 4.1e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Pyridoxal_deC PF00282.14 KUM62141.1 - 2.2e-109 365.3 0.0 2.6e-109 365.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Band_7_1 PF13421.1 KUM62141.1 - 0.097 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family adh_short_C2 PF13561.1 KUM62142.1 - 1.5e-13 51.0 0.0 1.7e-13 50.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ank_2 PF12796.2 KUM62143.1 - 2.3e-107 351.5 29.2 8.4e-17 61.3 2.6 18.8 3 3 13 17 17 17 17 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KUM62143.1 - 2.4e-77 254.0 31.0 6.5e-10 39.2 0.3 23.9 15 7 11 26 26 25 17 Ankyrin repeats (many copies) Ank PF00023.25 KUM62143.1 - 2e-72 235.6 61.9 1.1e-07 31.2 0.1 27.7 28 4 1 29 29 28 13 Ankyrin repeat Ank_3 PF13606.1 KUM62143.1 - 3.1e-63 203.3 36.9 8e-07 28.7 0.0 25.8 30 0 0 30 30 28 12 Ankyrin repeat Ank_5 PF13857.1 KUM62143.1 - 5.1e-60 198.1 53.9 8.6e-08 32.1 0.3 21.4 14 4 9 23 23 22 15 Ankyrin repeats (many copies) NACHT PF05729.7 KUM62143.1 - 2.7e-09 36.9 0.0 7.9e-09 35.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KUM62143.1 - 0.00029 20.8 0.1 0.0013 18.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_35 PF14516.1 KUM62143.1 - 0.0014 17.3 0.0 0.0029 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 KUM62143.1 - 0.0084 16.2 0.0 0.022 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KUM62143.1 - 0.01 15.5 0.0 0.1 12.3 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase DUF2075 PF09848.4 KUM62143.1 - 0.019 13.9 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MobB PF03205.9 KUM62143.1 - 0.081 12.6 0.0 0.37 10.4 0.0 2.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KUM62143.1 - 0.094 12.1 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain APS_kinase PF01583.15 KUM62143.1 - 0.11 12.2 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.17 KUM62143.1 - 0.26 10.1 0.0 0.49 9.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Pex2_Pex12 PF04757.9 KUM62144.1 - 4.7e-44 150.4 5.8 5.8e-44 150.2 4.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.20 KUM62144.1 - 4.8e-10 38.9 7.4 7.4e-10 38.3 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KUM62144.1 - 4.9e-10 39.2 9.7 7.6e-10 38.6 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KUM62144.1 - 1.1e-09 37.8 6.5 1.5e-09 37.3 4.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KUM62144.1 - 1.4e-09 37.6 10.0 2.2e-09 36.9 6.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KUM62144.1 - 8.3e-08 31.8 6.8 1.3e-07 31.1 4.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KUM62144.1 - 1.1e-05 25.1 8.5 1.9e-05 24.4 5.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KUM62144.1 - 2.1e-05 24.1 2.6 2.6e-05 23.8 0.9 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 KUM62144.1 - 0.00074 19.5 8.3 0.0017 18.3 5.8 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 KUM62144.1 - 0.0012 18.5 3.2 0.0022 17.7 2.2 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 KUM62144.1 - 0.057 13.2 3.5 0.096 12.5 2.1 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2851 PF11013.3 KUM62144.1 - 0.094 11.4 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2851) zf-RING_4 PF14570.1 KUM62144.1 - 0.11 12.0 7.6 0.21 11.2 5.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 KUM62144.1 - 0.13 11.7 3.1 0.28 10.7 2.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit IBR PF01485.16 KUM62144.1 - 0.95 9.3 7.2 2.4 8.0 4.8 1.8 1 1 0 1 1 1 0 IBR domain FYVE PF01363.16 KUM62144.1 - 2.5 8.0 6.6 9.5 6.2 4.6 1.9 1 1 0 1 1 1 0 FYVE zinc finger DNA_pol_A_exo1 PF01612.15 KUM62145.1 - 1.9e-18 66.5 0.0 5.5e-18 65.0 0.0 1.8 1 0 0 1 1 1 1 3'-5' exonuclease HTH_3 PF01381.17 KUM62145.1 - 0.061 13.1 0.2 14 5.6 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix DUF2744 PF10910.3 KUM62145.1 - 0.18 11.5 5.9 3.9 7.3 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2744) Nop25 PF09805.4 KUM62146.1 - 2.7e-35 121.4 16.2 2.7e-35 121.4 11.2 2.9 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) eIF3_p135 PF12807.2 KUM62146.1 - 2.3 8.1 11.6 10 5.9 8.1 2.0 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 DUF4604 PF15377.1 KUM62146.1 - 3.6 7.7 35.4 0.017 15.3 14.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4604) Cu_amine_oxid PF01179.15 KUM62147.1 - 5.7e-171 568.7 1.5 6.8e-171 568.5 1.1 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 KUM62147.1 - 1.4e-06 28.2 0.1 3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 KUM62147.1 - 6.9e-05 22.8 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain EXS PF03124.9 KUM62148.1 - 8.7e-94 314.3 15.5 9.9e-94 314.1 10.7 1.0 1 0 0 1 1 1 1 EXS family CMAS PF02353.15 KUM62149.1 - 7.1e-61 205.6 0.1 9.1e-61 205.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KUM62149.1 - 2.2e-11 43.7 0.0 4.1e-11 42.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM62149.1 - 2.1e-07 31.2 0.0 3.9e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM62149.1 - 1.3e-05 25.7 0.0 2.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM62149.1 - 3.7e-05 24.1 0.0 7.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KUM62149.1 - 0.0001 22.2 0.0 0.00021 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KUM62149.1 - 0.00014 21.3 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KUM62149.1 - 0.001 19.3 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM62149.1 - 0.0013 18.3 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 KUM62149.1 - 0.0053 16.0 0.0 0.0087 15.3 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 PCMT PF01135.14 KUM62149.1 - 0.024 14.1 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 KUM62149.1 - 0.029 13.7 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW FtsJ PF01728.14 KUM62149.1 - 0.051 13.5 0.1 0.09 12.7 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Tropomyosin_1 PF12718.2 KUM62151.1 - 2.2e-44 150.8 36.8 2.6e-44 150.5 25.5 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 KUM62151.1 - 5.4e-10 38.7 35.4 0.00013 21.1 9.8 2.8 1 1 1 2 2 2 2 Tropomyosin CENP-F_leu_zip PF10473.4 KUM62151.1 - 0.00093 19.0 6.2 0.00093 19.0 4.3 2.7 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF904 PF06005.7 KUM62151.1 - 0.0046 17.2 33.4 0.71 10.2 0.4 3.3 2 1 1 3 3 3 3 Protein of unknown function (DUF904) GAS PF13851.1 KUM62151.1 - 0.0084 15.3 30.7 0.068 12.3 14.5 2.2 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding CCDC155 PF14662.1 KUM62151.1 - 0.0095 15.5 34.5 0.019 14.5 11.1 2.1 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 IncA PF04156.9 KUM62151.1 - 0.011 15.3 34.7 0.39 10.2 17.6 2.2 1 1 1 2 2 2 0 IncA protein TBPIP PF07106.8 KUM62151.1 - 0.02 14.4 29.3 0.027 14.0 12.3 2.9 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) MAD PF05557.8 KUM62151.1 - 0.024 12.7 25.1 0.03 12.4 17.4 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Laminin_II PF06009.7 KUM62151.1 - 0.031 14.0 20.2 0.3 10.8 5.9 2.2 1 1 1 2 2 2 0 Laminin Domain II ERM PF00769.14 KUM62151.1 - 0.045 13.2 36.7 0.28 10.7 10.2 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Atg14 PF10186.4 KUM62151.1 - 0.076 11.9 29.2 0.14 11.1 16.0 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 KLRAQ PF10205.4 KUM62151.1 - 0.086 12.8 22.2 0.044 13.8 7.0 2.5 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein ATG16 PF08614.6 KUM62151.1 - 0.096 12.5 31.4 0.84 9.4 9.2 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) NABP PF07990.7 KUM62151.1 - 0.098 11.9 5.4 0.1 11.8 3.8 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP Mod_r PF07200.8 KUM62151.1 - 0.18 11.7 29.2 0.11 12.4 14.5 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Fmp27_WPPW PF10359.4 KUM62151.1 - 0.18 10.1 27.4 0.5 8.7 7.7 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF972 PF06156.8 KUM62151.1 - 0.19 12.0 28.2 0.34 11.2 7.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF4200 PF13863.1 KUM62151.1 - 0.25 11.2 33.5 0.28 11.1 11.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TMF_TATA_bd PF12325.3 KUM62151.1 - 0.32 10.7 28.6 3.6 7.3 14.6 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.3 KUM62151.1 - 0.41 10.5 33.7 7.6 6.4 10.2 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 KUM62151.1 - 0.59 9.2 7.0 1.1 8.4 4.8 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 KUM62151.1 - 0.59 9.8 36.0 0.71 9.6 7.0 2.9 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Striatin PF08232.7 KUM62151.1 - 0.61 10.4 25.4 0.71 10.1 12.6 2.1 1 1 1 2 2 2 0 Striatin family APG6 PF04111.7 KUM62151.1 - 0.81 8.6 35.1 2.5 7.0 12.2 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Nup54 PF13874.1 KUM62151.1 - 1.1 8.8 27.6 1.2 8.7 1.7 3.2 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 SlyX PF04102.7 KUM62151.1 - 1.7 9.1 23.6 0.99 9.8 4.9 3.5 1 1 0 2 2 2 0 SlyX DUF724 PF05266.9 KUM62151.1 - 1.9 8.0 29.5 0.31 10.6 7.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) bZIP_2 PF07716.10 KUM62151.1 - 3.1 7.6 35.7 1.9 8.3 2.0 5.0 2 2 2 4 4 4 0 Basic region leucine zipper DUF4140 PF13600.1 KUM62151.1 - 3.1 8.2 27.2 1.9 8.9 2.1 3.6 1 1 3 4 4 4 0 N-terminal domain of unknown function (DUF4140) TMF_DNA_bd PF12329.3 KUM62151.1 - 3.2 7.6 38.8 1.7 8.5 10.2 3.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.7 KUM62151.1 - 3.4 7.4 14.1 8.6 6.1 0.2 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.10 KUM62151.1 - 3.7 6.6 23.7 30 3.6 16.4 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit TMCO5 PF14992.1 KUM62151.1 - 4.3 6.4 29.5 15 4.5 13.7 2.0 1 1 1 2 2 2 0 TMCO5 family BssS PF13991.1 KUM62151.1 - 4.3 7.1 6.4 0.74 9.5 0.4 2.5 2 1 0 2 2 2 0 BssS protein family DUF745 PF05335.8 KUM62151.1 - 4.3 6.8 23.5 3.1 7.2 3.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF3450 PF11932.3 KUM62151.1 - 4.4 6.5 27.5 1.2 8.3 3.6 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) Spc7 PF08317.6 KUM62151.1 - 4.5 5.8 29.4 7.2 5.1 8.2 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF641 PF04859.7 KUM62151.1 - 5.8 6.6 21.4 0.4 10.4 4.1 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF4201 PF13870.1 KUM62151.1 - 7.2 6.0 30.4 2.9 7.3 16.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) bZIP_1 PF00170.16 KUM62151.1 - 8.1 6.4 31.5 3.8 7.5 0.8 4.8 1 1 3 4 4 4 0 bZIP transcription factor IFT46_B_C PF12317.3 KUM62151.1 - 8.8 5.6 9.6 2.9 7.2 4.1 1.7 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal PspA_IM30 PF04012.7 KUM62151.1 - 9 5.5 34.6 0.93 8.8 3.1 2.3 1 1 1 2 2 2 0 PspA/IM30 family MR_MLE_C PF13378.1 KUM62152.1 - 7.3e-21 74.2 0.0 1.3e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KUM62152.1 - 2.2e-12 47.2 0.0 4.3e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KUM62152.1 - 9e-10 38.5 0.0 1.5e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Amidohydro_2 PF04909.9 KUM62153.1 - 5.8e-14 52.3 0.0 9.6e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase UxaC PF02614.9 KUM62153.1 - 0.061 11.9 0.5 0.1 11.1 0.4 1.3 1 0 0 1 1 1 0 Glucuronate isomerase adh_short PF00106.20 KUM62154.1 - 8.9e-26 90.7 1.3 1.1e-25 90.4 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM62154.1 - 1.3e-21 77.4 0.0 1.5e-21 77.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM62154.1 - 2.7e-10 40.2 0.7 4.4e-10 39.5 0.5 1.3 1 0 0 1 1 1 1 KR domain Lactamase_B_2 PF12706.2 KUM62155.1 - 2.8e-25 89.0 0.0 3.7e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KUM62155.1 - 9e-10 38.4 0.0 1.2e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KUM62155.1 - 0.037 13.6 1.0 0.063 12.9 0.6 1.5 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Tub_2 PF04525.7 KUM62156.1 - 6.8e-10 38.6 0.0 8.9e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Tubby C 2 Sigma70_r3 PF04539.11 KUM62156.1 - 0.13 12.1 0.1 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-70 region 3 LSM PF01423.17 KUM62157.1 - 3.7e-19 68.0 0.0 4.2e-19 67.8 0.0 1.0 1 0 0 1 1 1 1 LSM domain AA_permease PF00324.16 KUM62158.1 - 9e-142 472.7 41.2 1.1e-141 472.4 28.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KUM62158.1 - 5.9e-38 130.5 39.7 8e-38 130.0 27.5 1.1 1 0 0 1 1 1 1 Amino acid permease RhoGAP PF00620.22 KUM62159.1 - 4.8e-15 55.4 0.1 1.1e-14 54.2 0.1 1.7 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 KUM62159.1 - 1.3e-12 47.7 0.0 5.5e-12 45.7 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 KUM62159.1 - 4.5e-08 32.7 0.0 9.8e-08 31.6 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Suppressor_APC PF11414.3 KUM62160.1 - 0.083 12.6 0.2 4.6 7.1 0.0 2.1 1 1 1 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein DUF1145 PF06611.7 KUM62161.1 - 0.049 13.2 0.1 6.8 6.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1145) Tap-RNA_bind PF09162.5 KUM62161.1 - 0.091 12.3 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Tap, RNA-binding FAM86 PF14904.1 KUM62161.1 - 0.13 12.0 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function DUF4595 PF15283.1 KUM62162.1 - 0.042 13.5 0.0 0.053 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4595) with porin-like fold CpeT PF06206.6 KUM62162.1 - 0.12 12.0 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 CpeT/CpcT family (DUF1001) PRKCSH-like PF12999.2 KUM62163.1 - 1.3e-43 148.5 14.4 8.4e-27 93.8 1.1 3.3 4 0 0 4 4 4 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 KUM62163.1 - 6.8e-33 113.3 8.0 9.8e-33 112.8 2.3 2.7 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 KUM62163.1 - 1.1e-07 32.5 2.4 3.1e-07 31.1 1.7 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein MRP-S25 PF13741.1 KUM62163.1 - 0.0028 17.1 0.8 0.0054 16.2 0.5 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 Fib_alpha PF08702.5 KUM62163.1 - 0.004 17.3 7.8 0.42 10.7 0.1 3.1 3 0 0 3 3 3 2 Fibrinogen alpha/beta chain family Sec8_exocyst PF04048.9 KUM62163.1 - 0.13 11.9 4.1 5.6 6.5 0.0 2.8 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain NPV_P10 PF05531.7 KUM62163.1 - 1 9.6 3.6 8 6.7 0.0 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.14 KUM62163.1 - 4.1 5.1 8.8 1.1 7.0 3.6 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Aldo_ket_red PF00248.16 KUM62164.1 - 1.3e-66 224.3 0.0 2.1e-66 223.6 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_S16 PF00886.14 KUM62164.1 - 0.037 13.7 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S16 MFS_1 PF07690.11 KUM62165.1 - 8.6e-36 123.3 32.7 1.7e-35 122.3 22.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 KUM62166.1 - 4.2e-45 154.0 0.1 5.8e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM62166.1 - 5.8e-05 22.9 12.3 0.00012 21.9 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L50 PF10501.4 KUM62167.1 - 1.7e-09 37.5 0.0 2.9e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal subunit 39S Pam16 PF03656.8 KUM62169.1 - 1.5e-31 108.8 0.5 1.8e-31 108.5 0.3 1.0 1 0 0 1 1 1 1 Pam16 Closter_coat PF01785.12 KUM62169.1 - 0.09 11.8 0.0 0.42 9.6 0.0 1.9 2 0 0 2 2 2 0 Closterovirus coat protein Pex24p PF06398.6 KUM62170.1 - 4.1e-99 331.7 0.6 5.9e-99 331.2 0.4 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Mating_C PF12737.2 KUM62172.1 - 0.68 8.7 5.4 0.75 8.6 3.8 1.0 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 PAP_assoc PF03828.14 KUM62173.1 - 3.2e-11 42.9 1.1 1.9e-10 40.5 0.5 2.4 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KUM62173.1 - 5.3e-09 36.2 0.0 1.1e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain adh_short PF00106.20 KUM62174.1 - 2.5e-14 53.5 0.0 3.8e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM62174.1 - 2.4e-12 47.1 0.0 2.1e-11 44.0 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KUM62174.1 - 2.5e-05 23.5 0.2 0.00011 21.4 0.1 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KUM62174.1 - 0.00014 21.9 0.0 0.00021 21.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KUM62174.1 - 0.0009 18.9 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 KUM62174.1 - 0.029 13.6 0.0 0.058 12.6 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family MFS_1 PF07690.11 KUM62175.1 - 7e-43 146.6 61.2 1.2e-41 142.5 40.4 3.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM62175.1 - 8.1e-16 57.3 29.1 1.2e-15 56.7 20.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KUM62175.1 - 3.1e-13 49.1 44.3 2.8e-12 45.9 12.1 2.9 3 1 1 4 4 4 2 Sugar (and other) transporter Fungal_trans PF04082.13 KUM62176.1 - 1.2e-25 89.8 0.5 1.8e-25 89.2 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM62176.1 - 3e-07 30.2 10.8 5e-07 29.5 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATP-synt_S1 PF05827.7 KUM62177.1 - 5.6e-60 203.0 0.1 6.5e-60 202.8 0.1 1.0 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) OAD_gamma PF04277.8 KUM62177.1 - 0.052 13.9 0.2 0.098 13.0 0.1 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain PAP1 PF08601.5 KUM62178.1 - 0.0046 16.6 26.0 0.0072 16.0 18.0 1.3 1 0 0 1 1 1 1 Transcription factor PAP1 Macoilin PF09726.4 KUM62178.1 - 0.081 11.1 21.2 0.099 10.9 14.7 1.1 1 0 0 1 1 1 0 Transmembrane protein SAPS PF04499.10 KUM62178.1 - 0.085 11.4 2.5 0.094 11.3 1.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MIP-T3 PF10243.4 KUM62178.1 - 0.55 8.6 10.4 0.68 8.3 7.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Tetraspannin PF00335.15 KUM62178.1 - 1.2 8.3 3.2 0.71 9.1 0.7 1.6 1 1 1 2 2 2 0 Tetraspanin family DUF2217 PF10265.4 KUM62178.1 - 2.1 7.0 11.0 3 6.5 7.6 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Thiolase_C PF02803.13 KUM62179.1 - 1.7e-44 150.1 1.0 2.5e-44 149.6 0.7 1.2 1 0 0 1 1 1 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 KUM62179.1 - 5.6e-15 55.0 0.3 9.7e-15 54.2 0.1 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Rtf2 PF04641.7 KUM62180.1 - 1.9e-66 223.9 0.2 2.6e-66 223.4 0.1 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 KUM62180.1 - 1.6e-09 37.1 0.2 0.002 17.5 0.0 3.3 2 1 1 3 3 3 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 KUM62180.1 - 9.1e-06 25.2 0.4 2.9e-05 23.6 0.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 KUM62180.1 - 0.00099 18.7 0.1 0.0022 17.6 0.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KUM62180.1 - 0.017 14.9 0.3 0.088 12.6 0.0 2.3 2 1 0 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.1 KUM62180.1 - 0.023 14.3 0.1 0.049 13.3 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KUM62180.1 - 0.062 13.3 0.1 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Amidase PF01425.16 KUM62181.1 - 3e-95 319.6 0.0 3.6e-95 319.4 0.0 1.1 1 0 0 1 1 1 1 Amidase Fungal_trans_2 PF11951.3 KUM62182.1 - 1.4e-11 43.6 0.1 7.7e-11 41.1 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM62182.1 - 1.9e-05 24.4 9.2 1.9e-05 24.4 6.4 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 KUM62183.1 - 1.8e-14 53.5 0.0 2.8e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM62183.1 - 0.00011 21.3 0.0 0.00018 20.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KUM62183.1 - 0.019 14.7 0.1 0.053 13.2 0.0 1.7 2 1 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 KUM62183.1 - 0.094 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DUF3632 PF12311.3 KUM62184.1 - 1.6e-33 116.1 0.2 2.1e-33 115.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) DUF4070 PF13282.1 KUM62184.1 - 0.12 11.8 0.2 0.28 10.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4070) Polyketide_cyc2 PF10604.4 KUM62186.1 - 0.00026 21.1 14.2 0.015 15.4 9.9 2.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 KUM62186.1 - 0.0021 18.0 2.0 0.0021 18.0 1.4 2.1 2 1 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport JAB PF01398.16 KUM62188.1 - 1.2e-13 50.7 0.0 2.9e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 KUM62188.1 - 1e-09 38.3 1.5 1.6e-09 37.6 1.0 1.3 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 KUM62188.1 - 2.5e-05 23.7 0.0 6.4e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain 4HBT PF03061.17 KUM62189.1 - 8.1e-08 32.2 0.0 1.2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily HET PF06985.6 KUM62191.1 - 1.5e-08 34.9 0.2 3.2e-08 33.8 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RRM_1 PF00076.17 KUM62193.1 - 5.9e-20 70.6 0.0 8.4e-20 70.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM62193.1 - 5.9e-14 51.8 0.0 8.1e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM62193.1 - 2.3e-10 40.1 0.0 3.2e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KUM62193.1 - 0.015 15.1 0.1 0.034 13.9 0.1 1.5 1 1 0 1 1 1 0 RNA binding motif WD40 PF00400.27 KUM62195.1 - 2e-32 109.8 3.4 6.7e-11 41.6 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Gmad1 PF10647.4 KUM62195.1 - 5e-06 26.0 0.2 1.2e-05 24.7 0.1 1.5 1 1 1 2 2 2 1 Lipoprotein LpqB beta-propeller domain PQQ_2 PF13360.1 KUM62195.1 - 7.4e-05 22.3 0.6 0.00016 21.2 0.3 1.6 1 1 0 1 1 1 1 PQQ-like domain Nup160 PF11715.3 KUM62195.1 - 0.0023 16.1 0.1 0.0034 15.5 0.1 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 ChaC PF04752.7 KUM62198.1 - 2.2e-53 180.8 0.0 2.8e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein DUF3433 PF11915.3 KUM62199.1 - 1.5e-43 146.8 14.5 2.5e-23 82.0 0.7 3.4 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) adh_short PF00106.20 KUM62200.1 - 6.2e-13 49.0 0.0 1.2e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM62200.1 - 8e-07 28.8 0.0 1.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM62200.1 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Zn_clus PF00172.13 KUM62201.1 - 4.3e-05 23.3 7.8 0.00013 21.8 5.4 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_32N PF00251.15 KUM62202.1 - 1.8e-43 149.0 0.1 1.5e-42 146.0 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 KUM62202.1 - 4.7e-15 55.7 0.0 8.4e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 KUM62202.1 - 0.019 14.7 0.2 0.019 14.7 0.1 2.7 2 0 0 2 2 2 0 BNR/Asp-box repeat Ank_2 PF12796.2 KUM62205.1 - 2.5e-50 168.7 8.0 3.4e-16 59.3 0.1 4.1 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KUM62205.1 - 8.4e-47 154.7 11.0 1.3e-06 27.8 0.1 8.4 7 1 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 KUM62205.1 - 1e-31 108.7 2.0 1.3e-07 31.8 0.0 7.4 3 1 5 8 8 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM62205.1 - 1.3e-21 76.1 7.6 1.1e-05 25.4 0.1 6.9 2 1 5 7 7 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM62205.1 - 1.1e-19 68.5 0.1 0.11 12.7 0.0 8.2 8 0 0 8 8 7 5 Ankyrin repeat NACHT PF05729.7 KUM62205.1 - 8e-08 32.1 0.0 2e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KUM62205.1 - 0.0026 17.9 0.4 0.025 14.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain DUF1843 PF08898.5 KUM62205.1 - 0.011 15.7 6.7 1.7 8.7 0.2 4.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) PPR_3 PF13812.1 KUM62205.1 - 0.039 14.2 0.2 12 6.4 0.0 3.5 3 0 0 3 3 3 0 Pentatricopeptide repeat domain AAA_14 PF13173.1 KUM62205.1 - 0.048 13.5 0.0 0.54 10.1 0.0 2.5 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KUM62205.1 - 0.061 12.1 0.1 0.18 10.6 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain ING PF12998.2 KUM62205.1 - 0.098 12.9 0.2 0.098 12.9 0.1 2.7 3 0 0 3 3 2 0 Inhibitor of growth proteins N-terminal histone-binding Arch_ATPase PF01637.13 KUM62205.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase DUF3235 PF11574.3 KUM62206.1 - 0.087 13.0 1.3 0.11 12.7 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) eIF-5_eIF-2B PF01873.12 KUM62207.1 - 3e-43 146.4 0.2 4.4e-43 145.8 0.1 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 KUM62207.1 - 0.096 13.0 0.7 0.31 11.3 0.5 2.0 1 1 0 1 1 1 0 Restriction alleviation protein Lar DUF3408 PF11888.3 KUM62207.1 - 0.66 9.8 4.5 1.3 8.9 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Arc_trans_TRASH PF08394.5 KUM62207.1 - 1.3 9.2 7.2 0.98 9.6 0.3 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain AIM24 PF01987.12 KUM62208.1 - 3.8e-45 153.9 0.1 4.3e-45 153.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Ank_2 PF12796.2 KUM62209.1 - 9.2e-34 115.6 5.5 4.9e-15 55.6 0.1 4.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KUM62209.1 - 1.7e-29 101.6 7.9 3e-10 40.3 0.1 5.7 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 KUM62209.1 - 1.7e-28 96.9 14.6 4.2e-09 35.7 0.3 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 KUM62209.1 - 8e-24 83.1 15.8 1.8e-12 47.0 0.2 5.2 2 1 5 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM62209.1 - 9.5e-18 62.5 4.5 7.1e-05 22.6 0.1 6.8 8 0 0 8 8 8 3 Ankyrin repeat ICL PF00463.16 KUM62209.1 - 0.24 9.5 0.0 0.37 8.9 0.0 1.2 1 0 0 1 1 1 0 Isocitrate lyase family SH3_1 PF00018.23 KUM62210.1 - 5.1e-14 51.3 0.0 7.9e-14 50.7 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KUM62210.1 - 1.1e-12 47.2 0.0 2.7e-12 46.0 0.0 1.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KUM62210.1 - 1.1e-08 34.3 0.0 1.8e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain MCPVI PF02993.9 KUM62210.1 - 3.7 7.6 10.6 0.59 10.2 4.7 1.6 2 0 0 2 2 2 0 Minor capsid protein VI TFIIA PF03153.8 KUM62210.1 - 3.7 7.3 5.6 4.2 7.1 3.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 KUM62210.1 - 4 5.5 16.9 4.8 5.2 11.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MBF1 PF08523.5 KUM62211.1 - 5.7e-23 80.7 1.0 1.1e-22 79.8 0.7 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 KUM62211.1 - 4e-09 36.1 0.1 6.8e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 KUM62211.1 - 0.00018 21.6 0.0 0.00037 20.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 KUM62211.1 - 0.00072 19.5 0.1 0.0012 18.8 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain DUF4618 PF15397.1 KUM62211.1 - 0.1 11.8 0.1 0.15 11.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) FTHFS PF01268.14 KUM62212.1 - 9.7e-256 849.1 0.1 1.3e-255 848.6 0.1 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 KUM62212.1 - 4.9e-67 224.0 0.8 1.1e-66 222.8 0.5 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 KUM62212.1 - 1.6e-35 121.6 0.3 6.2e-35 119.7 0.5 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GTP_EFTU PF00009.22 KUM62212.1 - 0.01 15.2 0.2 0.03 13.7 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Iso_dh PF00180.15 KUM62214.1 - 9e-69 232.0 0.0 1.1e-68 231.7 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF2543 PF10820.3 KUM62214.1 - 0.097 12.6 0.1 0.26 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2543) CAP_GLY PF01302.20 KUM62216.1 - 1.5e-27 95.1 0.0 2.3e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 KUM62216.1 - 8.2e-14 51.6 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 KUM62216.1 - 5e-05 22.6 0.0 0.00019 20.7 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family Mif2_N PF15624.1 KUM62217.1 - 3.6e-37 127.9 5.9 3.6e-37 127.9 4.1 4.1 4 1 1 5 5 5 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.3 KUM62217.1 - 5.5e-37 125.6 0.7 9.6e-37 124.8 0.5 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 KUM62217.1 - 8.1e-07 28.4 0.0 2.3e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 Cupin domain HNF-1_N PF04814.8 KUM62217.1 - 2.3 8.3 6.9 0.49 10.4 0.5 2.4 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus RNase_HII PF01351.13 KUM62218.1 - 2.2e-45 154.7 0.0 3e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII Pex16 PF08610.5 KUM62219.1 - 1.9e-114 382.1 0.0 2.1e-114 382.0 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) SAE2 PF08573.5 KUM62220.1 - 8.1e-30 103.3 0.1 8.1e-30 103.3 0.1 3.4 3 0 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Histone_HNS PF00816.16 KUM62220.1 - 0.00016 22.1 4.9 0.0012 19.3 0.3 3.0 2 0 0 2 2 2 1 H-NS histone family bZIP_1 PF00170.16 KUM62220.1 - 0.011 15.7 3.8 0.03 14.2 0.8 2.8 2 0 0 2 2 2 0 bZIP transcription factor F-box PF00646.28 KUM62221.1 - 3.7e-07 29.6 0.7 3.7e-07 29.6 0.5 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KUM62221.1 - 1.9e-05 24.2 0.4 3.5e-05 23.4 0.3 1.5 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 KUM62221.1 - 0.00034 20.3 0.6 0.78 9.7 0.3 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat zf-CCHC PF00098.18 KUM62222.1 - 4e-50 165.4 60.5 4.7e-09 35.7 1.0 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 KUM62222.1 - 1.6e-12 46.8 44.1 0.036 13.7 0.4 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 KUM62222.1 - 7.6e-05 22.3 54.1 0.01 15.5 1.1 6.7 3 2 4 7 7 7 6 Zinc knuckle zf-CCHC_6 PF15288.1 KUM62222.1 - 0.00051 19.6 45.6 0.018 14.7 1.3 6.8 4 2 3 7 7 7 4 Zinc knuckle zf-CCHC_2 PF13696.1 KUM62222.1 - 0.021 14.3 40.5 0.046 13.2 0.2 7.1 3 2 4 7 7 7 0 Zinc knuckle UPF0061 PF02696.9 KUM62223.1 - 2.3e-121 405.4 0.0 2.8e-121 405.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family MA3 PF02847.12 KUM62223.1 - 0.19 11.4 0.0 0.39 10.4 0.0 1.4 1 0 0 1 1 1 0 MA3 domain Myb_DNA-binding PF00249.26 KUM62224.1 - 2.2e-11 43.6 2.3 6.4e-09 35.7 0.0 2.9 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KUM62224.1 - 6.3e-07 29.4 4.7 0.0002 21.4 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Methyltransf_11 PF08241.7 KUM62225.1 - 1.2e-14 54.5 0.0 2.1e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM62225.1 - 2.1e-08 34.4 0.0 3.6e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM62225.1 - 5.3e-08 32.7 0.0 1.5e-07 31.3 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM62225.1 - 3.7e-06 27.3 0.1 6.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM62225.1 - 5.8e-05 22.7 0.0 8.4e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM62225.1 - 0.0022 18.5 0.0 0.0044 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 KUM62225.1 - 0.0043 16.2 0.0 0.0066 15.6 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.6 KUM62225.1 - 0.023 13.3 0.0 0.079 11.6 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Reprolysin_5 PF13688.1 KUM62227.1 - 5.9e-29 101.4 4.2 1.1e-28 100.5 2.9 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KUM62227.1 - 2.4e-23 82.7 1.0 2.4e-23 82.7 0.7 1.6 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KUM62227.1 - 2.6e-16 60.1 0.9 2.6e-16 60.1 0.7 2.4 2 1 1 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KUM62227.1 - 7.8e-13 49.0 0.3 2e-12 47.7 0.2 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like SPT16 PF08644.6 KUM62228.1 - 1.7e-58 196.7 0.0 4e-58 195.5 0.0 1.7 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 KUM62228.1 - 9e-56 187.8 0.3 2.9e-55 186.2 0.1 2.1 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 KUM62228.1 - 1.6e-25 89.8 0.0 2.7e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 KUM62228.1 - 6e-20 71.0 0.0 1.4e-19 69.8 0.0 1.7 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Arc_PepC PF06819.6 KUM62228.1 - 0.003 17.4 0.0 0.47 10.3 0.0 2.9 2 0 0 2 2 2 1 Archaeal Peptidase A24 C-terminal Domain Choline_transpo PF04515.7 KUM62229.1 - 9.5e-08 31.1 16.1 9.5e-08 31.1 11.1 3.1 3 0 0 3 3 3 2 Plasma-membrane choline transporter Peptidase_M43 PF05572.8 KUM62230.1 - 6.3e-14 51.8 0.1 5.1e-13 48.9 0.0 2.1 1 1 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 KUM62230.1 - 8.6e-06 25.8 5.0 1.9e-05 24.6 3.5 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KUM62230.1 - 0.00082 19.9 0.4 0.0016 18.9 0.3 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KUM62230.1 - 0.032 13.7 0.9 0.043 13.3 0.7 1.4 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KUM62230.1 - 0.19 11.7 2.7 0.25 11.4 1.9 1.4 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Mito_carr PF00153.22 KUM62231.1 - 2.6e-21 75.1 1.9 3.9e-15 55.3 0.0 2.8 2 1 0 2 2 2 2 Mitochondrial carrier protein Sugar_tr PF00083.19 KUM62233.1 - 8.8e-101 337.6 13.9 1.1e-100 337.4 9.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM62233.1 - 2.1e-29 102.3 30.0 4.7e-27 94.6 18.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KUM62233.1 - 5.2e-09 35.0 17.5 1.7e-05 23.4 3.7 2.9 3 0 0 3 3 3 2 MFS/sugar transport protein Tmemb_18A PF09771.4 KUM62233.1 - 0.24 11.3 1.5 4.7 7.2 0.0 2.9 2 1 1 3 3 3 0 Transmembrane protein 188 PMT PF02366.13 KUM62234.1 - 1.1e-84 283.6 15.4 1.1e-84 283.6 10.7 2.1 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KUM62234.1 - 5.9e-39 133.5 0.1 8.7e-39 133.0 0.1 1.2 1 0 0 1 1 1 1 MIR domain Ras PF00071.17 KUM62235.1 - 1.1e-47 161.3 0.0 4.3e-37 127.0 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KUM62235.1 - 1.5e-15 57.6 0.0 2.2e-14 53.9 0.0 2.2 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 KUM62235.1 - 1.8e-11 43.6 0.0 6.4e-11 41.8 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KUM62235.1 - 7.5e-10 38.5 0.0 1.9e-08 33.9 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KUM62235.1 - 4.9e-05 22.5 0.0 0.00016 20.8 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KUM62235.1 - 0.00024 21.0 0.0 0.0014 18.5 0.0 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.1 KUM62235.1 - 0.0033 17.0 0.1 0.056 13.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KUM62235.1 - 0.0038 17.3 0.0 0.014 15.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain Flu_M1_C PF08289.6 KUM62235.1 - 0.024 14.6 0.1 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain AAA_16 PF13191.1 KUM62235.1 - 0.17 11.8 0.2 0.42 10.5 0.2 1.5 1 0 0 1 1 1 0 AAA ATPase domain Aldo_ket_red PF00248.16 KUM62237.1 - 1.9e-47 161.4 0.0 2.3e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Atg8 PF02991.11 KUM62238.1 - 2.5e-51 171.9 0.2 3e-51 171.7 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KUM62238.1 - 2.5e-06 27.5 0.0 3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Coprogen_oxidas PF01218.13 KUM62239.1 - 4.8e-120 399.5 0.0 1.2e-119 398.3 0.0 1.6 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase HOOK PF05622.7 KUM62240.1 - 1.1e-24 86.3 34.8 1.1e-24 86.3 24.1 2.7 1 1 0 2 2 2 1 HOOK protein Tropomyosin PF00261.15 KUM62240.1 - 0.0065 15.5 10.9 0.0065 15.5 7.6 4.5 2 2 1 3 3 3 1 Tropomyosin Prefoldin_2 PF01920.15 KUM62240.1 - 0.012 15.4 1.8 0.012 15.4 1.3 9.3 5 2 1 7 7 7 0 Prefoldin subunit DUF812 PF05667.6 KUM62240.1 - 0.03 12.8 47.0 0.028 12.9 20.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DUF1411 PF07199.6 KUM62240.1 - 0.046 13.1 4.3 0.1 12.0 0.7 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1411) Reo_sigmaC PF04582.7 KUM62240.1 - 0.3 10.2 18.3 0.029 13.5 1.6 3.3 2 2 1 3 3 3 0 Reovirus sigma C capsid protein CCDC155 PF14662.1 KUM62240.1 - 1.2 8.7 81.7 4.8 6.7 16.0 5.0 2 1 3 5 5 5 0 Coiled-coil region of CCDC155 Spc7 PF08317.6 KUM62240.1 - 1.2 7.7 66.2 0.036 12.7 4.5 4.8 3 1 2 5 5 5 0 Spc7 kinetochore protein AAA_27 PF13514.1 KUM62240.1 - 3.3 5.2 61.1 2.3 5.8 35.1 3.0 1 1 1 2 2 2 0 AAA domain TBPIP PF07106.8 KUM62240.1 - 3.5 7.1 69.4 0.017 14.6 3.3 6.9 3 2 3 7 7 7 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fib_alpha PF08702.5 KUM62240.1 - 3.8 7.6 51.2 0.04 14.0 5.6 5.6 3 2 2 6 6 6 0 Fibrinogen alpha/beta chain family Mito_carr PF00153.22 KUM62241.1 - 7.5e-27 92.8 2.3 8.9e-15 54.1 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein CTD_bind PF04818.8 KUM62242.1 - 0.0037 17.4 0.0 0.0097 16.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRN7 PF11781.3 KUM62242.1 - 0.02 14.3 1.5 0.16 11.4 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 CFIA_Pcf11 PF11526.3 KUM62242.1 - 0.024 14.7 0.6 0.061 13.4 0.4 1.6 1 0 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 VHS PF00790.14 KUM62242.1 - 0.1 12.2 0.0 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 VHS domain zf-C2HC_2 PF13913.1 KUM62242.1 - 0.5 10.0 7.1 1.3 8.7 0.4 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Inhibitor_I9 PF05922.11 KUM62243.1 - 0.0014 19.1 0.0 0.0022 18.4 0.0 1.4 1 1 0 1 1 1 1 Peptidase inhibitor I9 DUF3186 PF11382.3 KUM62243.1 - 0.031 13.4 0.0 0.032 13.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) ADK PF00406.17 KUM62244.1 - 3.7e-60 202.1 0.0 4.8e-60 201.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KUM62244.1 - 5.8e-14 51.4 0.0 1.7e-13 49.9 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.1 KUM62244.1 - 9.4e-06 25.5 0.0 1.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KUM62244.1 - 1.4e-05 25.9 0.0 2.1e-05 25.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KUM62244.1 - 0.00011 22.5 0.0 0.00021 21.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KUM62244.1 - 0.0066 15.5 0.0 0.0098 14.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 KUM62244.1 - 0.037 13.9 0.0 0.059 13.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain Myosin_tail_1 PF01576.14 KUM62244.1 - 0.059 11.0 0.1 0.089 10.4 0.0 1.2 1 0 0 1 1 1 0 Myosin tail Thymidylate_kin PF02223.12 KUM62244.1 - 0.065 12.6 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 Thymidylate kinase GFO_IDH_MocA PF01408.17 KUM62245.1 - 1.4e-18 67.5 0.1 2.1e-18 67.0 0.1 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KUM62245.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain UCH PF00443.24 KUM62246.1 - 2.4e-22 79.3 0.0 5.2e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KUM62246.1 - 1.1e-07 31.5 0.0 1.7e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CDC45 PF02724.9 KUM62246.1 - 1.4 6.9 15.2 2.6 5.9 10.5 1.4 1 0 0 1 1 1 0 CDC45-like protein Prog_receptor PF02161.10 KUM62246.1 - 2.4 6.8 7.5 6.1 5.5 5.2 1.7 1 0 0 1 1 1 0 Progesterone receptor MitMem_reg PF13012.1 KUM62247.1 - 4.1e-40 136.4 0.3 8.8e-40 135.3 0.1 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 KUM62247.1 - 4.8e-29 100.3 0.0 1e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease NARP1 PF12569.3 KUM62247.1 - 0.1 11.3 4.3 0.17 10.5 3.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CDC50 PF03381.10 KUM62248.1 - 1.5e-97 326.1 0.0 1.8e-97 325.8 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF4282 PF14110.1 KUM62248.1 - 0.14 12.3 2.1 1.5 9.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) AIG2 PF06094.7 KUM62250.1 - 4.4e-11 43.1 0.0 5.6e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family SWIRM PF04433.12 KUM62251.1 - 6.4e-15 55.0 0.0 1.2e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain PH PF00169.24 KUM62253.1 - 2.6e-10 40.4 0.1 9.4e-10 38.6 0.1 2.0 2 0 0 2 2 2 1 PH domain DUF3632 PF12311.3 KUM62254.1 - 4e-28 98.4 9.0 5.2e-28 98.0 6.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) DUF2370 PF10176.4 KUM62255.1 - 1.4e-87 292.9 0.9 1.9e-87 292.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) PBP1_TM PF14812.1 KUM62255.1 - 1.8 8.9 6.7 4.6 7.6 4.7 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.20 KUM62256.1 - 7.6e-71 238.2 0.0 9.8e-71 237.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM62256.1 - 5.3e-31 107.6 0.0 8.3e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KUM62256.1 - 0.051 13.2 2.4 0.055 13.1 0.1 2.2 2 2 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KUM62256.1 - 0.085 11.9 0.0 0.23 10.5 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rb_C PF08934.5 KUM62257.1 - 0.0035 16.9 0.1 0.013 15.1 0.0 2.0 1 0 0 1 1 1 1 Rb C-terminal domain UCH PF00443.24 KUM62258.1 - 2.8e-49 167.6 0.0 4.8e-49 166.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 KUM62258.1 - 2.7e-43 145.1 0.4 5.5e-20 70.5 0.0 4.5 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.1 KUM62258.1 - 2.8e-12 46.6 1.0 2e-06 27.4 0.0 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.5 KUM62258.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 PUB domain Tim17 PF02466.14 KUM62259.1 - 1.6e-13 50.8 7.5 2.5e-13 50.1 5.2 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family CoA_trans PF01144.18 KUM62261.1 - 6.6e-101 335.9 1.1 2.6e-60 203.3 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase tRNA-synt_2b PF00587.20 KUM62262.1 - 3.1e-43 147.3 0.1 5.4e-43 146.5 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KUM62262.1 - 5e-17 61.6 0.1 1.5e-16 60.1 0.1 1.9 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 KUM62262.1 - 3.2e-14 52.5 0.0 6.4e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 KUM62262.1 - 0.00037 20.2 0.0 0.00087 19.0 0.0 1.6 1 0 0 1 1 1 1 TGS domain G_glu_transpept PF01019.16 KUM62263.1 - 4.7e-142 474.0 0.1 5.5e-142 473.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Clusterin PF01093.12 KUM62264.1 - 0.27 10.0 1.5 0.38 9.5 1.0 1.2 1 0 0 1 1 1 0 Clusterin Gar1 PF04410.9 KUM62266.1 - 1.3e-42 144.8 1.3 1.9e-42 144.3 0.1 1.7 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region CDP-OH_P_transf PF01066.16 KUM62267.1 - 1.9e-11 44.1 2.4 1.9e-11 44.1 1.7 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase WSC PF01822.14 KUM62268.1 - 4.3e-13 48.9 10.8 4.3e-13 48.9 7.5 2.3 2 1 0 2 2 2 1 WSC domain SKG6 PF08693.5 KUM62268.1 - 8.9e-10 37.7 0.8 8.9e-10 37.7 0.5 2.9 4 0 0 4 4 4 1 Transmembrane alpha-helix domain Plasmodium_Vir PF05795.6 KUM62268.1 - 0.013 14.7 0.6 0.015 14.4 0.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4448 PF14610.1 KUM62268.1 - 0.018 14.5 0.1 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Dicty_REP PF05086.7 KUM62268.1 - 0.02 12.7 1.0 0.022 12.5 0.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3611 PF12263.3 KUM62268.1 - 0.067 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) Mucin PF01456.12 KUM62268.1 - 0.19 11.5 19.1 0.33 10.7 13.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Podoplanin PF05808.6 KUM62268.1 - 0.37 10.3 9.1 0.56 9.7 6.3 1.2 1 0 0 1 1 1 0 Podoplanin DUF2076 PF09849.4 KUM62268.1 - 2.7 7.9 7.1 5 7.1 5.0 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) zf-C2H2_4 PF13894.1 KUM62269.1 - 5.6e-07 29.4 5.0 0.0019 18.3 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KUM62269.1 - 0.0023 18.1 0.9 0.0023 18.1 0.7 3.0 3 0 0 3 3 3 1 Zinc finger, C2H2 type COQ9 PF08511.6 KUM62270.1 - 6.8e-21 73.5 0.1 1.2e-20 72.7 0.1 1.4 1 0 0 1 1 1 1 COQ9 DUF935 PF06074.7 KUM62270.1 - 0.023 13.4 0.1 0.031 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF935) RRM_1 PF00076.17 KUM62271.1 - 1.6e-40 136.6 0.0 7.2e-17 60.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM62271.1 - 2.7e-34 116.9 0.0 3.6e-15 55.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM62271.1 - 6.9e-22 77.0 0.0 2.1e-07 30.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KUM62271.1 - 0.0033 17.1 0.2 15 5.4 0.1 4.1 3 2 0 3 3 3 1 Limkain b1 PknH_C PF14032.1 KUM62271.1 - 0.063 12.8 1.9 25 4.3 0.1 3.1 3 0 0 3 3 3 0 PknH-like extracellular domain ATP-grasp_2 PF08442.5 KUM62271.1 - 0.086 12.2 0.0 0.42 9.9 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain RRM_3 PF08777.6 KUM62271.1 - 0.1 12.4 0.0 7.7 6.4 0.0 2.8 3 0 0 3 3 3 0 RNA binding motif THRAP3_BCLAF1 PF15440.1 KUM62271.1 - 6.3 5.3 26.7 8 4.9 18.5 1.2 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Glyco_hydro_47 PF01532.15 KUM62272.1 - 2.2e-170 567.1 0.0 2.6e-170 566.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF2013 PF09431.5 KUM62273.1 - 1.7e-51 173.6 2.2 4.1e-51 172.4 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) APG9 PF04109.11 KUM62274.1 - 2.5e-169 563.0 2.0 3.2e-169 562.6 1.4 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 DUF4404 PF14357.1 KUM62275.1 - 0.0003 21.1 0.0 0.00043 20.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4404) Nop14 PF04147.7 KUM62276.1 - 0.14 10.0 14.9 0.18 9.7 10.3 1.0 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 KUM62276.1 - 9.5 5.3 11.7 13 4.8 8.1 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Sas10_Utp3 PF04000.10 KUM62277.1 - 1.6e-16 60.2 0.6 3.7e-16 59.0 0.4 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family TT_ORF2 PF02957.10 KUM62277.1 - 0.26 12.0 9.8 0.12 13.1 2.0 2.6 2 0 0 2 2 2 0 TT viral ORF2 UQ_con PF00179.21 KUM62279.1 - 5.9e-44 148.8 0.0 6.7e-44 148.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RVT_2 PF07727.9 KUM62280.1 - 6.4e-37 126.8 0.0 5.8e-36 123.7 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 KUM62280.1 - 0.0024 17.2 0.0 0.021 14.1 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mito_carr PF00153.22 KUM62281.1 - 2e-60 200.5 7.2 1.9e-20 72.3 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4653 PF15546.1 KUM62281.1 - 4.7 6.4 7.0 10 5.3 4.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4653) EF-hand_7 PF13499.1 KUM62282.1 - 4.3e-29 100.4 10.7 1.6e-13 50.5 0.6 3.1 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 KUM62282.1 - 8e-26 87.3 11.5 5.2e-08 31.6 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 KUM62282.1 - 5.3e-25 85.0 3.3 6.2e-06 25.6 0.0 5.2 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 KUM62282.1 - 1.3e-17 62.2 11.9 9.5e-05 21.5 0.0 4.8 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 KUM62282.1 - 1.5e-15 56.4 12.2 5.2e-06 25.9 1.1 4.3 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 KUM62282.1 - 5e-09 35.8 5.6 0.0029 17.3 0.1 3.6 1 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KUM62282.1 - 0.00014 21.7 0.4 0.063 13.2 0.0 3.3 2 1 1 3 3 3 1 EF-hand domain EF-hand_10 PF14788.1 KUM62282.1 - 0.001 18.6 1.7 0.62 9.7 0.0 3.7 4 0 0 4 4 4 1 EF hand DUF1679 PF07914.6 KUM62282.1 - 0.015 13.9 0.3 1.2 7.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) SPARC_Ca_bdg PF10591.4 KUM62282.1 - 0.043 13.8 0.9 1.7 8.7 0.1 3.0 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region TFIIIC_delta PF12657.2 KUM62283.1 - 5.8e-26 91.2 0.1 9.7e-26 90.5 0.1 1.4 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 KUM62283.1 - 8.6e-11 41.6 0.1 2.1e-10 40.3 0.1 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex Thiolase_N PF00108.18 KUM62284.1 - 7.6e-94 313.5 0.6 1.3e-93 312.8 0.4 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KUM62284.1 - 9.5e-39 131.6 1.3 9.5e-39 131.6 0.9 2.0 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KUM62284.1 - 0.00012 21.6 1.9 0.00012 21.6 1.3 2.5 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KUM62284.1 - 6.4 6.5 7.0 7.5 6.2 0.2 3.2 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III UQ_con PF00179.21 KUM62285.1 - 9.1e-52 174.2 0.0 1e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KUM62285.1 - 1.6e-05 24.6 0.0 1.9e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KUM62285.1 - 0.041 13.7 0.1 0.11 12.3 0.1 1.7 1 1 0 1 1 1 0 RWD domain Aminotran_1_2 PF00155.16 KUM62286.1 - 5.7e-61 206.4 0.0 6.9e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aa_trans PF01490.13 KUM62287.1 - 1.8e-47 161.7 35.8 2.1e-47 161.5 24.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DHDPS PF00701.17 KUM62288.1 - 2.8e-39 134.4 0.1 3.5e-39 134.1 0.1 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family TPR_3 PF07720.7 KUM62288.1 - 0.074 12.8 0.3 0.25 11.1 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat NAD_binding_4 PF07993.7 KUM62289.1 - 1.2e-36 125.9 0.0 1.4e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KUM62289.1 - 5.2e-05 22.7 0.0 7.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KUM62289.1 - 0.0012 17.8 0.0 0.0016 17.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KUM62289.1 - 0.047 13.6 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Cation_efflux PF01545.16 KUM62291.1 - 3.4e-52 177.2 11.2 3.4e-52 177.2 7.7 3.1 3 0 0 3 3 3 1 Cation efflux family Neur_chan_memb PF02932.11 KUM62291.1 - 2 8.2 8.1 5.2 6.8 0.1 3.0 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region Glyco_trans_1_4 PF13692.1 KUM62292.1 - 5.6e-31 107.4 0.0 3.2e-30 105.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 KUM62292.1 - 0.0001 21.8 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KUM62292.1 - 0.001 19.2 0.0 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 KUM62292.1 - 0.0012 19.0 0.0 0.0023 18.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 ABC_membrane PF00664.18 KUM62293.1 - 4.5e-73 246.0 31.1 3e-38 131.8 11.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KUM62293.1 - 2.2e-54 183.4 0.0 2.9e-33 115.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KUM62293.1 - 2.5e-12 46.5 0.3 1.2e-05 24.6 0.0 3.4 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KUM62293.1 - 9e-11 42.2 0.0 1.1e-05 25.5 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KUM62293.1 - 6.3e-10 38.4 0.3 0.00027 20.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KUM62293.1 - 6.9e-10 39.7 0.0 0.0023 18.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KUM62293.1 - 1.7e-09 38.3 0.2 0.00091 19.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KUM62293.1 - 2.7e-08 34.0 0.2 0.013 15.4 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 KUM62293.1 - 5e-08 32.2 0.0 0.008 15.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KUM62293.1 - 7.8e-08 32.5 0.0 0.0093 16.1 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KUM62293.1 - 3.2e-07 30.6 0.0 0.013 15.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain ABC_ATPase PF09818.4 KUM62293.1 - 5.3e-06 25.2 3.6 0.0047 15.5 0.1 3.6 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_25 PF13481.1 KUM62293.1 - 1.3e-05 24.6 0.1 0.15 11.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.1 KUM62293.1 - 1.7e-05 24.7 0.1 0.22 11.3 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KUM62293.1 - 6.4e-05 22.6 0.0 0.29 10.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 KUM62293.1 - 8.9e-05 22.5 0.0 0.16 11.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KUM62293.1 - 0.00013 21.6 0.2 1.4 8.7 0.0 3.3 3 0 0 3 3 3 2 Part of AAA domain Rad17 PF03215.10 KUM62293.1 - 0.00028 19.7 0.0 0.063 11.9 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein MobB PF03205.9 KUM62293.1 - 0.00053 19.6 0.0 0.25 11.0 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KUM62293.1 - 0.00059 19.3 1.2 0.7 9.2 0.0 3.6 4 0 0 4 4 3 1 AAA-like domain AAA_14 PF13173.1 KUM62293.1 - 0.00063 19.6 0.0 0.5 10.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KUM62293.1 - 0.00079 19.6 0.1 1.2 9.2 0.0 3.8 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.1 KUM62293.1 - 0.0012 18.0 0.0 0.093 11.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.1 KUM62293.1 - 0.0029 17.2 0.0 2.6 7.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 KUM62293.1 - 0.004 17.2 0.0 1.9 8.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase DUF87 PF01935.12 KUM62293.1 - 0.0045 16.8 0.6 3 7.6 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function DUF87 PRK PF00485.13 KUM62293.1 - 0.0046 16.5 0.0 0.94 8.9 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.18 KUM62293.1 - 0.005 16.7 0.2 2.3 8.2 0.1 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase NB-ARC PF00931.17 KUM62293.1 - 0.0099 14.7 0.0 0.59 8.9 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain Zeta_toxin PF06414.7 KUM62293.1 - 0.01 14.9 0.1 6.6 5.7 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin ATP-synt_ab PF00006.20 KUM62293.1 - 0.014 14.9 0.1 5.6 6.3 0.0 2.6 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain Guanylate_kin PF00625.16 KUM62293.1 - 0.04 13.3 0.2 7.6 5.9 0.0 2.7 3 0 0 3 3 2 0 Guanylate kinase APS_kinase PF01583.15 KUM62293.1 - 0.042 13.5 0.0 13 5.4 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase G-alpha PF00503.15 KUM62293.1 - 0.049 12.3 0.0 3.7 6.1 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit NACHT PF05729.7 KUM62293.1 - 0.066 12.8 0.0 15 5.1 0.0 2.7 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.10 KUM62293.1 - 0.086 12.5 0.1 39 3.9 0.0 3.3 3 0 0 3 3 3 0 NTPase FtsK_SpoIIIE PF01580.13 KUM62293.1 - 0.15 11.5 0.0 0.76 9.2 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family RTA1 PF04479.8 KUM62294.1 - 7e-44 149.9 3.6 9.6e-44 149.5 2.5 1.1 1 0 0 1 1 1 1 RTA1 like protein DctQ PF04290.7 KUM62294.1 - 0.017 14.8 0.7 0.017 14.8 0.5 2.7 2 1 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF2231 PF09990.4 KUM62294.1 - 1.4 9.2 7.1 0.64 10.3 0.3 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2231) Chitin_synth_1 PF01644.12 KUM62295.1 - 2.3e-23 82.7 0.1 3.7e-23 82.1 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 KUM62295.1 - 5.3e-23 81.2 0.0 1.7e-20 72.9 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KUM62295.1 - 2.9e-09 36.9 11.5 2.9e-09 36.9 8.0 2.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KUM62295.1 - 5.3e-09 36.2 0.0 8.3e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Muted PF14942.1 KUM62295.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein adh_short PF00106.20 KUM62296.1 - 1.5e-11 44.4 0.0 3.4e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase MFS_1 PF07690.11 KUM62297.1 - 6.8e-37 126.9 45.1 6.8e-37 126.9 31.3 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily FMN_dh PF01070.13 KUM62298.1 - 1.4e-107 359.6 0.0 1.7e-107 359.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KUM62298.1 - 2.8e-05 23.2 0.0 4.2e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KUM62298.1 - 0.00053 18.9 0.5 0.0096 14.8 0.3 2.6 3 1 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KUM62298.1 - 0.0085 15.2 0.1 0.016 14.3 0.1 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 KUM62298.1 - 0.11 11.8 0.0 9 5.4 0.0 2.3 2 0 0 2 2 2 0 Histidine biosynthesis protein DHO_dh PF01180.16 KUM62298.1 - 0.14 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Hydantoinase_B PF02538.9 KUM62299.1 - 3e-188 626.3 0.0 3.7e-188 626.0 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KUM62299.1 - 8e-95 317.2 0.1 1.7e-92 309.6 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KUM62299.1 - 1.9e-56 190.3 0.0 2.1e-53 180.4 0.0 2.7 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Fungal_trans PF04082.13 KUM62300.1 - 7.9e-21 74.0 0.1 1.6e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cyclase PF04199.8 KUM62300.1 - 3.8e-13 49.4 0.0 6.6e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Putative cyclase Zn_clus PF00172.13 KUM62300.1 - 5.5e-08 32.5 8.8 1.1e-07 31.6 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase_2 PF01510.20 KUM62300.1 - 0.024 14.7 0.2 0.071 13.1 0.1 1.8 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase Chitin_synth_1 PF01644.12 KUM62301.1 - 2.4e-27 95.7 0.0 3.2e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KUM62301.1 - 3.1e-27 94.0 0.1 4.8e-27 93.4 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase N-terminal PACT_coil_coil PF10495.4 KUM62301.1 - 0.073 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein FMO-like PF00743.14 KUM62302.1 - 2.9e-18 65.3 0.0 4.6e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KUM62302.1 - 1.3e-15 58.0 0.0 6.2e-15 55.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KUM62302.1 - 5.3e-10 38.7 0.0 1.3e-08 34.1 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KUM62302.1 - 0.00016 21.6 0.0 0.0086 15.9 0.0 2.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KUM62302.1 - 0.016 15.3 0.0 0.076 13.1 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KUM62302.1 - 0.018 15.4 0.5 0.038 14.3 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KUM62302.1 - 0.02 15.1 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 KUM62302.1 - 0.024 14.3 0.1 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_4 PF01565.18 KUM62303.1 - 2e-14 53.2 0.0 3.2e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Kinesin PF00225.18 KUM62305.1 - 1.9e-111 372.0 0.0 4.4e-111 370.8 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain Filament PF00038.16 KUM62305.1 - 0.45 9.9 60.0 1.1 8.6 23.3 4.3 2 1 1 3 3 3 0 Intermediate filament protein IncA PF04156.9 KUM62305.1 - 1.3 8.6 65.4 0.12 11.9 0.8 6.0 2 1 2 5 5 5 0 IncA protein XkdW PF09636.5 KUM62305.1 - 1.3 8.8 6.3 9.8 6.1 0.2 3.2 2 0 0 2 2 2 0 XkdW protein EMP70 PF02990.11 KUM62306.1 - 3.9e-188 626.1 0.0 3.9e-188 626.1 0.0 1.3 2 0 0 2 2 2 1 Endomembrane protein 70 His_Phos_1 PF00300.17 KUM62307.1 - 7.9e-10 39.0 0.0 8.5e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) 5_nucleotid_C PF02872.13 KUM62308.1 - 2.5e-32 111.9 0.0 7e-32 110.5 0.0 1.7 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 KUM62308.1 - 1.1e-09 37.9 0.4 1.7e-09 37.3 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TFIIIC_delta PF12657.2 KUM62309.1 - 5.2e-08 32.7 0.2 7.5e-08 32.2 0.1 1.2 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term GspL_C PF12693.2 KUM62310.1 - 0.066 12.9 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 GspL periplasmic domain TPR_10 PF13374.1 KUM62312.1 - 3.5e-46 153.8 0.0 1.3e-10 40.8 0.0 5.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 KUM62312.1 - 1.2e-43 146.9 0.0 1.1e-12 47.7 0.0 5.3 2 1 4 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 KUM62312.1 - 9.2e-13 46.9 0.0 0.14 12.0 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat NB-ARC PF00931.17 KUM62312.1 - 9.4e-13 47.6 0.0 3.2e-12 45.9 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain TPR_17 PF13431.1 KUM62312.1 - 6.9e-08 32.1 0.0 3.4 8.0 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat NACHT PF05729.7 KUM62312.1 - 5.2e-05 22.9 0.0 0.0001 22.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain TPR_1 PF00515.23 KUM62312.1 - 0.0012 18.3 0.0 41 4.0 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 KUM62312.1 - 0.0015 19.1 0.0 0.41 11.3 0.0 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat AAA_16 PF13191.1 KUM62312.1 - 0.0025 17.8 1.4 0.022 14.7 0.3 2.9 2 1 0 2 2 2 1 AAA ATPase domain Rab5-bind PF09311.6 KUM62312.1 - 0.0048 16.8 0.4 0.1 12.4 0.1 2.5 1 1 1 2 2 2 1 Rabaptin-like protein AAA_22 PF13401.1 KUM62312.1 - 0.014 15.5 0.0 0.036 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KUM62312.1 - 0.033 13.6 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain TPR_19 PF14559.1 KUM62312.1 - 0.042 14.1 0.0 22 5.4 0.0 3.8 2 1 2 4 4 4 0 Tetratricopeptide repeat AAA_5 PF07728.9 KUM62312.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Proteasome_A_N PF10584.4 KUM62312.1 - 0.13 11.5 0.9 84 2.6 0.0 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Rotavirus_VP3 PF06929.6 KUM62312.1 - 0.17 9.7 0.0 0.24 9.2 0.0 1.1 1 0 0 1 1 1 0 Rotavirus VP3 protein DUF4637 PF15470.1 KUM62313.1 - 1.3 8.6 5.2 3.4 7.2 3.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF1664 PF07889.7 KUM62313.1 - 6 6.6 6.6 13 5.6 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) tRNA_m1G_MT PF01746.16 KUM62314.1 - 3.4e-29 101.7 0.0 2.9e-28 98.7 0.0 2.2 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase DUF4050 PF13259.1 KUM62314.1 - 0.053 13.4 0.1 0.053 13.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Hom_end_hint PF05203.11 KUM62314.1 - 9.3 5.9 8.0 5 6.7 0.1 2.7 2 1 0 2 2 2 0 Hom_end-associated Hint VID27 PF08553.5 KUM62315.1 - 0 1156.6 5.5 0 1156.4 3.8 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein Dynamin_M PF01031.15 KUM62316.1 - 3.2e-13 49.1 0.2 9.6e-13 47.5 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 KUM62316.1 - 1.9e-08 34.3 0.0 4.4e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Proho_convert PF12177.3 KUM62316.1 - 0.039 13.5 0.3 2.1 8.0 0.0 2.6 2 0 0 2 2 2 0 Prohormone convertase enzyme TLD PF07534.11 KUM62317.1 - 4.9e-25 88.1 0.0 1.6e-14 54.1 0.0 2.2 2 0 0 2 2 2 2 TLD Neuropep_like PF15161.1 KUM62318.1 - 0.043 13.2 11.7 3.1 7.3 0.4 3.6 1 1 2 3 3 3 0 Neuropeptide-like TBCC PF07986.7 KUM62320.1 - 2.5e-34 117.2 0.3 3.9e-34 116.6 0.2 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C Halo_GVPC PF05465.8 KUM62320.1 - 0.33 10.9 2.0 2.2 8.2 0.1 2.5 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat Pro-kuma_activ PF09286.6 KUM62321.1 - 3.5e-21 75.7 1.0 9.6e-21 74.3 0.0 2.2 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KUM62321.1 - 6.1e-08 32.1 0.0 9.4e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Subtilase family SAC3_GANP PF03399.11 KUM62322.1 - 1.4e-22 80.3 0.0 1.6e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KUM62322.1 - 3.6e-20 72.2 0.0 5.2e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 DEK_C PF08766.6 KUM62323.1 - 0.0026 17.4 0.1 0.0064 16.2 0.0 1.7 1 0 0 1 1 1 1 DEK C terminal domain Evr1_Alr PF04777.8 KUM62324.1 - 2.2e-25 88.3 5.3 2.2e-25 88.3 3.7 1.8 2 0 0 2 2 2 1 Erv1 / Alr family Lamp PF01299.12 KUM62324.1 - 1.8 7.6 8.4 2.3 7.2 5.8 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Coatomer_WDAD PF04053.9 KUM62325.1 - 2.9e-152 507.5 0.0 1.1e-151 505.6 0.0 1.9 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.6 KUM62325.1 - 5.1e-92 308.6 0.0 7.3e-92 308.1 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 KUM62325.1 - 1.2e-50 167.6 11.2 2.4e-09 36.7 0.0 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 KUM62325.1 - 0.017 13.3 6.9 1.5 6.8 0.0 3.9 1 1 1 4 4 4 0 Nucleoporin Nup120/160 WD40 PF00400.27 KUM62327.1 - 0.035 14.0 3.8 1.1 9.3 0.0 4.4 5 0 0 5 5 5 0 WD domain, G-beta repeat MFS_1 PF07690.11 KUM62328.1 - 1.5e-40 139.0 25.4 1.3e-35 122.7 11.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KUM62328.1 - 0.12 12.1 0.1 0.12 12.1 0.1 3.3 3 1 0 3 3 3 0 MFS_1 like family UNC-93 PF05978.11 KUM62328.1 - 0.38 10.2 8.7 0.7 9.3 2.5 3.1 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 GRIM-19 PF06212.7 KUM62329.1 - 1.4e-22 79.8 0.2 2.6e-22 78.9 0.2 1.4 1 1 0 1 1 1 1 GRIM-19 protein EHN PF06441.7 KUM62331.1 - 8.2e-35 119.1 0.0 1.3e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KUM62331.1 - 2.5e-11 43.8 0.8 4.6e-11 43.0 0.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM62331.1 - 1.7e-08 34.2 1.3 4.8e-08 32.8 0.0 2.4 3 0 0 3 3 3 1 alpha/beta hydrolase fold DIOX_N PF14226.1 KUM62332.1 - 7.6e-32 110.2 0.0 1.3e-31 109.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KUM62332.1 - 5e-21 74.8 0.0 9.1e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Vps51 PF08700.6 KUM62333.1 - 3e-27 94.3 0.0 6.7e-27 93.1 0.0 1.6 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.4 KUM62333.1 - 0.017 15.0 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 ResIII PF04851.10 KUM62333.1 - 0.058 13.2 0.1 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Dor1 PF04124.7 KUM62333.1 - 0.088 11.2 0.1 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 Dor1-like family Sec5 PF15469.1 KUM62333.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.6 1 1 0 1 1 1 0 Exocyst complex component Sec5 DUF1917 PF08939.5 KUM62334.1 - 5.6e-73 245.6 0.0 6.5e-73 245.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) DUF4455 PF14643.1 KUM62334.1 - 0.093 11.3 0.8 0.16 10.5 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) TPR_11 PF13414.1 KUM62335.1 - 4.9e-30 102.9 50.4 2e-06 27.3 0.4 12.5 9 4 4 14 14 14 10 TPR repeat TPR_16 PF13432.1 KUM62335.1 - 9.2e-30 102.6 51.7 2.2e-05 25.0 0.4 12.6 13 1 1 14 14 12 7 Tetratricopeptide repeat TPR_14 PF13428.1 KUM62335.1 - 1e-22 78.5 51.6 7.5e-05 23.0 0.1 16.3 14 4 4 18 18 15 4 Tetratricopeptide repeat TPR_17 PF13431.1 KUM62335.1 - 1.4e-20 71.7 20.7 0.06 13.5 0.0 14.0 16 0 0 16 16 13 5 Tetratricopeptide repeat TPR_2 PF07719.12 KUM62335.1 - 1.2e-19 68.5 50.5 0.0008 19.1 0.1 14.8 15 0 0 15 15 15 5 Tetratricopeptide repeat TPR_1 PF00515.23 KUM62335.1 - 1.9e-19 68.3 36.2 0.00062 19.2 0.0 12.0 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_19 PF14559.1 KUM62335.1 - 4.3e-18 65.4 26.1 0.0022 18.3 0.1 9.7 7 2 3 10 10 9 6 Tetratricopeptide repeat TPR_12 PF13424.1 KUM62335.1 - 1.9e-13 50.1 45.0 3.3e-08 33.3 0.9 11.5 10 3 3 13 13 12 3 Tetratricopeptide repeat TPR_6 PF13174.1 KUM62335.1 - 2.2e-13 49.6 25.0 0.00023 21.4 0.1 11.8 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_8 PF13181.1 KUM62335.1 - 2e-12 45.9 33.5 0.0015 18.2 0.0 11.6 12 1 1 13 13 11 4 Tetratricopeptide repeat Apc3 PF12895.2 KUM62335.1 - 3e-10 40.0 20.9 6.7e-06 26.1 0.5 7.0 7 0 0 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KUM62335.1 - 8.9e-09 34.5 20.4 0.0037 16.9 0.0 9.7 10 1 1 11 11 10 2 Tetratricopeptide repeat TPR_9 PF13371.1 KUM62335.1 - 0.0031 17.3 22.7 0.76 9.6 1.9 6.2 5 2 2 7 7 7 3 Tetratricopeptide repeat ChAPs PF09295.5 KUM62335.1 - 0.0053 15.5 1.8 8.2 5.0 0.0 4.8 6 1 1 7 7 7 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.1 KUM62335.1 - 1.1 9.4 0.0 1.1 9.4 0.0 7.1 6 2 1 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.1 KUM62335.1 - 5.9 6.9 22.7 1.4 8.9 0.4 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF1767 PF08585.7 KUM62336.1 - 1.1e-21 76.8 0.4 1.6e-21 76.3 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Xpo1 PF08389.7 KUM62337.1 - 4.5e-11 42.8 2.3 9.2e-06 25.6 0.0 3.6 3 0 0 3 3 3 2 Exportin 1-like protein HEAT_2 PF13646.1 KUM62337.1 - 6.2e-05 23.2 0.2 0.00051 20.2 0.0 2.6 2 0 0 2 2 2 1 HEAT repeats Cellulase PF00150.13 KUM62338.1 - 1.1e-07 31.3 6.4 9.1e-07 28.3 2.6 2.7 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) LRR_4 PF12799.2 KUM62339.1 - 0.00042 19.8 0.0 0.00055 19.4 0.0 1.3 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) EntA_Immun PF08951.5 KUM62339.1 - 0.014 15.5 0.1 0.019 15.1 0.1 1.2 1 0 0 1 1 1 0 Enterocin A Immunity Adaptin_N PF01602.15 KUM62340.1 - 2.5e-149 498.0 2.9 3.2e-149 497.6 2.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KUM62340.1 - 1.2e-30 106.7 0.6 1.3e-26 93.5 0.0 3.1 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KUM62340.1 - 6.8e-20 71.1 1.6 1.5e-08 34.8 0.0 5.8 4 2 2 6 6 6 4 HEAT repeats HEAT PF02985.17 KUM62340.1 - 3.1e-11 42.3 2.5 0.016 15.2 0.0 6.5 7 0 0 7 7 7 3 HEAT repeat CLASP_N PF12348.3 KUM62340.1 - 4.7e-05 22.8 0.9 0.41 9.9 0.0 4.4 3 2 1 4 4 4 2 CLASP N terminal HEAT_EZ PF13513.1 KUM62340.1 - 0.00034 20.9 4.1 1.2 9.7 0.0 6.4 7 1 1 8 8 8 1 HEAT-like repeat Arm PF00514.18 KUM62340.1 - 0.0016 18.1 0.9 12 5.8 0.0 5.1 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat DUF2817 PF10994.3 KUM62340.1 - 0.13 11.3 0.1 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) Thr_synth_N PF14821.1 KUM62341.1 - 1.7e-29 101.6 0.0 6.2e-29 99.8 0.0 2.0 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 KUM62341.1 - 3.3e-14 52.8 0.0 8.2e-14 51.5 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Sugar_tr PF00083.19 KUM62342.1 - 2.4e-74 250.5 26.2 2.9e-74 250.2 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM62342.1 - 9.3e-17 60.7 53.6 5.5e-14 51.6 18.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MgtE PF01769.11 KUM62342.1 - 0.18 12.1 10.3 2.1 8.6 0.2 2.8 2 1 0 2 2 2 0 Divalent cation transporter NmrA PF05368.8 KUM62343.1 - 3.5e-11 42.8 0.0 7.5e-06 25.3 0.0 2.1 1 1 1 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 KUM62343.1 - 0.096 12.6 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding RsbRD_N PF14361.1 KUM62343.1 - 0.098 13.1 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain Profilin PF00235.14 KUM62344.1 - 4e-32 110.8 0.1 4.5e-32 110.7 0.1 1.0 1 0 0 1 1 1 1 Profilin ADH_N PF08240.7 KUM62345.1 - 6.8e-26 90.1 5.2 1.2e-25 89.3 3.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM62345.1 - 2.6e-16 59.3 0.0 4.3e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KUM62345.1 - 1.1e-06 29.6 0.0 1.8e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KUM62345.1 - 0.0082 15.3 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_4 PF01565.18 KUM62346.1 - 3.6e-19 68.6 0.6 6.8e-19 67.7 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KUM62346.1 - 1.1e-09 38.0 1.9 2.3e-09 36.9 1.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KUM62346.1 - 0.12 11.4 0.2 0.2 10.7 0.2 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Rick_17kDa_Anti PF05433.10 KUM62347.1 - 0.0021 17.7 16.0 0.0021 17.7 11.1 2.0 2 0 0 2 2 2 1 Glycine zipper 2TM domain DUF533 PF04391.7 KUM62347.1 - 0.0029 16.9 6.5 0.0039 16.5 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF533) MarC PF01914.12 KUM62347.1 - 0.0044 16.1 0.1 0.006 15.7 0.0 1.1 1 0 0 1 1 1 1 MarC family integral membrane protein DUF1637 PF07847.7 KUM62347.1 - 1.3 8.3 5.5 10 5.4 3.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1637) DUF1183 PF06682.7 KUM62347.1 - 3.2 7.2 12.3 4 6.9 8.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) Gly-zipper_OmpA PF13436.1 KUM62347.1 - 4.4 6.9 21.1 0.28 10.8 8.8 2.1 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain ABC_tran PF00005.22 KUM62349.1 - 1e-50 171.5 0.0 9.3e-31 106.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KUM62349.1 - 1.1e-26 93.8 35.3 1.2e-16 60.9 6.4 3.0 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 KUM62349.1 - 3.4e-08 33.0 3.6 0.094 11.9 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KUM62349.1 - 2e-06 27.3 0.6 0.037 13.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 KUM62349.1 - 3.7e-05 24.1 0.1 0.01 16.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KUM62349.1 - 0.00013 21.3 2.7 0.41 10.2 0.4 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 KUM62349.1 - 0.0002 21.4 1.8 4.8 7.0 0.0 4.1 3 1 0 3 3 3 1 AAA domain T2SE PF00437.15 KUM62349.1 - 0.00029 19.8 0.2 0.073 11.9 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF87 PF01935.12 KUM62349.1 - 0.00065 19.5 1.4 0.12 12.1 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_16 PF13191.1 KUM62349.1 - 0.0009 19.2 3.8 0.096 12.6 0.1 3.0 2 1 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 KUM62349.1 - 0.002 18.0 0.1 0.47 10.4 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.1 KUM62349.1 - 0.0055 16.6 0.0 4.5 7.2 0.0 3.6 3 0 0 3 3 3 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 KUM62349.1 - 0.0057 15.8 0.2 1.5 7.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 KUM62349.1 - 0.013 14.6 0.2 4.9 6.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.13 KUM62349.1 - 0.013 14.9 0.1 6.2 6.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF2075 PF09848.4 KUM62349.1 - 0.017 14.0 2.2 0.54 9.1 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) Miro PF08477.8 KUM62349.1 - 0.017 15.5 1.5 4.6 7.7 0.1 3.0 3 0 0 3 3 2 0 Miro-like protein AAA_22 PF13401.1 KUM62349.1 - 0.044 13.9 3.2 21 5.2 0.0 3.7 4 0 0 4 4 3 0 AAA domain AAA_10 PF12846.2 KUM62349.1 - 0.077 12.4 4.9 3.5 6.9 0.1 3.1 2 1 0 3 3 3 0 AAA-like domain AAA_30 PF13604.1 KUM62349.1 - 0.17 11.4 0.3 92 2.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 KUM62349.1 - 0.19 12.5 2.1 3.9 8.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KUM62349.1 - 0.26 11.0 0.3 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KUM62349.1 - 0.29 10.7 3.9 9.7 5.8 0.0 3.3 3 0 0 3 3 3 0 NACHT domain cobW PF02492.14 KUM62349.1 - 0.71 9.2 2.6 3.3 7.1 0.3 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain p450 PF00067.17 KUM62350.1 - 8.5e-51 172.8 0.0 1.1e-50 172.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 P5CR_dimer PF14748.1 KUM62351.1 - 3.1e-28 97.8 0.4 5.8e-28 97.0 0.3 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KUM62351.1 - 7.9e-07 29.4 0.0 9.5e-05 22.7 0.0 3.3 3 1 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent AMP-binding PF00501.23 KUM62352.1 - 0 1166.3 0.0 3.9e-74 249.5 0.0 5.2 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.15 KUM62352.1 - 4.7e-186 616.7 0.0 2.8e-40 138.0 0.0 5.5 5 0 0 5 5 5 5 Condensation domain PP-binding PF00550.20 KUM62352.1 - 4.4e-51 171.0 10.2 5.1e-11 42.6 0.0 6.3 7 0 0 7 7 7 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KUM62352.1 - 2.7e-22 79.5 1.8 3.9e-06 27.7 0.2 5.7 5 0 0 5 5 5 3 AMP-binding enzyme C-terminal domain GH3 PF03321.8 KUM62352.1 - 8.2e-06 24.6 0.2 1.1 7.6 0.0 5.9 6 0 0 6 6 6 1 GH3 auxin-responsive promoter Transferase PF02458.10 KUM62352.1 - 0.31 9.4 0.0 6.1 5.1 0.0 2.7 3 0 0 3 3 3 0 Transferase family Prismane PF03063.15 KUM62352.1 - 5 5.3 0.1 17 3.6 0.0 1.8 2 0 0 2 2 2 0 Prismane/CO dehydrogenase family DIOX_N PF14226.1 KUM62353.1 - 5.6e-21 75.2 0.0 9.6e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KUM62353.1 - 1.1e-11 44.8 0.0 1.9e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sugar_tr PF00083.19 KUM62354.1 - 9.7e-81 271.6 28.0 1.1e-80 271.4 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM62354.1 - 2.4e-29 102.1 26.2 2.4e-29 102.1 18.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KUM62354.1 - 0.56 10.2 6.7 0.68 9.9 0.2 4.0 3 2 2 5 5 5 0 Protein of unknown function (DUF1228) F420_oxidored PF03807.12 KUM62355.1 - 7.2e-06 26.3 0.0 1.7e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 KUM62355.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GMC_oxred_N PF00732.14 KUM62356.1 - 5.7e-45 153.7 0.4 9.9e-45 152.9 0.3 1.4 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KUM62356.1 - 2.1e-28 99.4 0.0 3.5e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KUM62356.1 - 1.7e-06 27.1 7.1 3.1e-05 23.0 4.8 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KUM62356.1 - 2.4e-06 26.6 1.9 0.0076 15.1 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KUM62356.1 - 1.5e-05 24.9 0.3 3.6e-05 23.6 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KUM62356.1 - 0.00013 21.0 0.2 0.0002 20.4 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 KUM62356.1 - 0.014 13.8 0.1 0.023 13.1 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.9 KUM62356.1 - 0.032 14.1 0.1 0.064 13.1 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SH3_1 PF00018.23 KUM62357.1 - 0.067 12.5 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 SH3 domain TauD PF02668.11 KUM62358.1 - 8.7e-12 45.2 0.1 1e-11 45.0 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KUM62358.1 - 0.019 13.8 0.0 0.026 13.4 0.0 1.1 1 0 0 1 1 1 0 CsiD Transferase PF02458.10 KUM62359.1 - 3.6e-19 68.5 0.0 4.8e-15 54.9 0.0 2.0 2 0 0 2 2 2 2 Transferase family EMP24_GP25L PF01105.19 KUM62361.1 - 4.9e-48 163.2 0.6 4.9e-48 163.2 0.4 1.3 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD Glycoprotein PF03409.10 KUM62361.1 - 0.054 12.2 0.0 0.08 11.6 0.0 1.3 1 0 0 1 1 1 0 Transmembrane glycoprotein ketoacyl-synt PF00109.21 KUM62362.1 - 6.8e-77 258.3 0.0 1.5e-76 257.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KUM62362.1 - 5e-70 236.3 0.4 7.6e-70 235.7 0.3 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KUM62362.1 - 1.2e-47 161.8 0.0 3.3e-47 160.4 0.0 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 KUM62362.1 - 5.4e-44 150.5 0.0 1.1e-43 149.4 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KUM62362.1 - 8e-42 142.9 0.1 2.5e-41 141.3 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KUM62362.1 - 1.4e-39 134.6 0.1 8.1e-39 132.1 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KUM62362.1 - 2.5e-19 69.5 0.0 8.7e-19 67.8 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KUM62362.1 - 5.4e-17 61.5 0.3 3.6e-16 58.8 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KUM62362.1 - 1.4e-11 44.4 0.0 2.7e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM62362.1 - 6e-11 42.6 0.0 1.6e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM62362.1 - 3e-08 33.4 0.0 1.2e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.7 KUM62362.1 - 6e-07 29.2 0.1 1.4e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.13 KUM62362.1 - 8.7e-07 28.2 0.0 1.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KUM62362.1 - 1.9e-06 28.3 0.0 1.4e-05 25.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.18 KUM62362.1 - 7.8e-06 25.0 0.1 2.3e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_zinc_N_2 PF13602.1 KUM62362.1 - 1.6e-05 25.7 0.0 0.00011 23.1 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.20 KUM62362.1 - 2.9e-05 24.2 0.1 2.9e-05 24.2 0.1 2.6 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_24 PF13578.1 KUM62362.1 - 0.065 14.0 0.0 0.25 12.1 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain FSH1 PF03959.8 KUM62363.1 - 2.4e-29 102.3 0.0 3.8e-29 101.6 0.0 1.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KUM62363.1 - 5.8e-05 22.8 0.0 0.00011 22.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KUM62363.1 - 0.053 12.9 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PAM2 PF07145.10 KUM62364.1 - 0.16 11.5 19.3 0.51 9.9 0.0 4.6 4 0 0 4 4 4 0 Ataxin-2 C-terminal region Glyco_hydro_17 PF00332.13 KUM62365.1 - 4.2e-31 108.1 0.0 1.5e-30 106.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 FAD_binding_4 PF01565.18 KUM62366.1 - 4.1e-14 52.2 1.3 7.1e-14 51.4 0.9 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KUM62366.1 - 0.0038 17.0 0.1 0.012 15.5 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like ADH_zinc_N PF00107.21 KUM62367.1 - 2.8e-16 59.2 0.0 4.6e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM62367.1 - 1.8e-06 27.6 0.2 2.7e-05 23.8 0.2 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain FA_desaturase PF00487.19 KUM62369.1 - 4e-37 128.0 30.2 8.3e-37 127.0 20.9 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KUM62369.1 - 1.8e-13 50.0 0.0 3.7e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DASH_Dad3 PF08656.5 KUM62370.1 - 2.1e-25 88.2 2.1 2.8e-25 87.7 1.5 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad3 Pkinase PF00069.20 KUM62372.1 - 2e-70 236.9 0.0 3.3e-70 236.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM62372.1 - 6.4e-30 104.0 0.0 2.1e-21 76.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KUM62372.1 - 1.7e-08 33.7 0.2 0.005 15.8 0.0 3.1 2 1 1 3 3 3 2 Kinase-like APH PF01636.18 KUM62372.1 - 0.032 13.9 0.0 1.6 8.3 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF4026 PF13218.1 KUM62372.1 - 0.048 12.5 0.0 0.079 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4026) Kdo PF06293.9 KUM62372.1 - 0.074 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MCR_beta PF02241.13 KUM62372.1 - 0.1 11.8 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain Actin PF00022.14 KUM62373.1 - 2.3e-90 302.8 0.0 6.4e-90 301.3 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KUM62373.1 - 0.047 12.2 0.0 1.4 7.4 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Ribosomal_S5_C PF03719.10 KUM62375.1 - 1.8e-16 59.1 0.0 3.6e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 KUM62375.1 - 1.1e-06 28.2 0.1 7.4e-06 25.6 0.0 2.4 1 1 1 2 2 2 1 Ribosomal protein S5, N-terminal domain Acetyltransf_11 PF13720.1 KUM62375.1 - 0.086 13.0 2.7 6.8 6.9 0.0 2.8 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Tautomerase PF01361.16 KUM62375.1 - 0.12 11.9 0.1 0.8 9.3 0.1 2.2 2 0 0 2 2 2 0 Tautomerase enzyme tRNA_U5-meth_tr PF05958.6 KUM62376.1 - 1.8e-12 46.6 0.0 1e-10 40.8 0.0 2.4 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 KUM62376.1 - 1.9e-05 24.3 0.0 3.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.15 KUM62376.1 - 0.00011 21.9 1.0 0.00024 20.8 0.2 2.0 2 0 0 2 2 2 1 TRAM domain Methyltransf_15 PF09445.5 KUM62376.1 - 0.015 14.8 0.0 0.036 13.6 0.0 1.7 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 KUM62376.1 - 0.043 12.9 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Asparaginase_2 PF01112.13 KUM62377.1 - 4.6e-38 130.7 3.2 6.3e-21 74.4 0.1 2.2 2 0 0 2 2 2 2 Asparaginase Tfb4 PF03850.9 KUM62378.1 - 1.3e-119 398.5 0.0 1.6e-119 398.2 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 SIMPL PF04402.9 KUM62379.1 - 8.5e-27 94.3 1.8 4.2e-26 92.1 1.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF541) Gly_rich PF12810.2 KUM62379.1 - 0.00021 21.0 0.2 0.00025 20.7 0.1 1.2 1 0 0 1 1 1 1 Glycine rich protein DUF4426 PF14467.1 KUM62379.1 - 0.0017 18.1 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4426) AA_permease_2 PF13520.1 KUM62380.1 - 1.7e-45 155.3 56.2 2.3e-45 154.9 38.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM62380.1 - 1.8e-27 95.8 48.9 2.4e-27 95.4 33.9 1.0 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.17 KUM62381.1 - 1.7e-48 165.3 0.0 4.1e-43 147.5 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Glyco_hydro_3 PF00933.16 KUM62383.1 - 3.3e-78 262.7 0.0 4.8e-78 262.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KUM62383.1 - 7.1e-58 195.7 0.0 2.6e-57 193.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KUM62383.1 - 3.3e-22 78.2 0.0 7.2e-22 77.1 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KUM62383.1 - 6.6e-11 42.0 0.0 1.2e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 PA14 domain TauD PF02668.11 KUM62384.1 - 4.5e-44 151.0 0.1 5.6e-44 150.7 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 KUM62385.1 - 5.5e-18 64.8 15.8 7e-18 64.4 10.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-C2H2_4 PF13894.1 KUM62387.1 - 4.2e-07 29.8 12.8 0.0001 22.3 1.7 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KUM62387.1 - 1.9e-05 24.7 10.1 0.015 15.5 0.8 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type ADH_zinc_N PF00107.21 KUM62388.1 - 3.3e-31 107.5 0.0 5.6e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KUM62388.1 - 3.9e-20 73.0 0.0 7.8e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM62388.1 - 1e-11 44.5 0.1 1.2e-10 41.0 0.0 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain IPK PF03770.11 KUM62389.1 - 7e-60 202.0 0.0 1e-59 201.5 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Arb1 PF09692.5 KUM62390.1 - 2.2e-115 385.7 0.7 3.3e-115 385.1 0.0 1.5 2 0 0 2 2 2 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Pox_VLTF3 PF04947.9 KUM62390.1 - 0.016 14.6 2.6 0.031 13.8 1.8 1.4 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like TFIID_30kDa PF03540.8 KUM62391.1 - 1.8e-23 82.1 0.1 2.6e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Ribosomal_S19 PF00203.16 KUM62392.1 - 8.3e-21 73.4 0.0 9.9e-21 73.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 His_Phos_2 PF00328.17 KUM62393.1 - 7.1e-11 42.0 0.0 9.4e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) TRF PF08558.5 KUM62394.1 - 2.3e-88 295.5 0.8 3.6e-88 294.9 0.5 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 KUM62394.1 - 1.6e-05 24.8 0.0 3.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Arginase PF00491.16 KUM62395.1 - 6.6e-88 294.6 0.0 7.7e-88 294.3 0.0 1.0 1 0 0 1 1 1 1 Arginase family Fungal_trans_2 PF11951.3 KUM62396.1 - 9.2e-51 172.6 4.8 1.3e-50 172.1 3.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM62396.1 - 3.2e-08 33.3 9.6 6.4e-08 32.3 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Polysacc_deac_1 PF01522.16 KUM62397.1 - 2.7e-19 69.0 0.0 4.7e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2194 PF09960.4 KUM62397.1 - 0.01 13.9 0.0 0.016 13.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) DUF2334 PF10096.4 KUM62397.1 - 0.014 14.8 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) DUF2721 PF11026.3 KUM62399.1 - 8.9 5.9 10.0 0.43 10.2 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) F-box-like PF12937.2 KUM62400.1 - 1.1e-05 25.0 2.0 2.8e-05 23.7 1.4 1.7 1 0 0 1 1 1 1 F-box-like APH PF01636.18 KUM62401.1 - 5.9e-06 26.1 0.0 6.8e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4476 PF14771.1 KUM62401.1 - 0.056 13.4 0.4 0.11 12.5 0.2 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4476) DNA_pol_B_3 PF08408.5 KUM62401.1 - 0.066 13.0 0.1 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase family B viral insert CD34_antigen PF06365.7 KUM62401.1 - 0.072 12.7 0.1 0.091 12.3 0.1 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family GDPD PF03009.12 KUM62403.1 - 2e-70 237.2 0.0 3.9e-70 236.2 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 KUM62403.1 - 2e-32 111.3 0.1 1e-15 57.8 0.1 3.9 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KUM62403.1 - 4.2e-30 103.5 2.3 4.5e-09 36.5 0.0 5.3 4 1 1 5 5 5 4 Ankyrin repeats (many copies) SPX PF03105.14 KUM62403.1 - 2.2e-28 99.7 6.6 6.6e-14 52.3 2.5 3.4 2 1 0 2 2 2 2 SPX domain Ank PF00023.25 KUM62403.1 - 2.3e-28 96.5 0.6 0.00016 21.3 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 KUM62403.1 - 4.3e-20 71.2 0.4 1.3e-06 28.4 0.0 5.3 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM62403.1 - 1.1e-18 65.4 0.1 0.0035 17.4 0.0 7.3 7 0 0 7 7 7 4 Ankyrin repeat UNC45-central PF11701.3 KUM62404.1 - 1.1e-39 135.6 0.7 1.3e-38 132.0 0.1 2.7 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.1 KUM62404.1 - 0.0016 18.7 3.6 0.0016 18.7 2.5 5.8 5 3 1 6 6 6 1 HEAT repeats TPR_11 PF13414.1 KUM62404.1 - 0.017 14.7 0.3 0.055 13.1 0.2 1.9 1 0 0 1 1 1 0 TPR repeat TPR_15 PF13429.1 KUM62404.1 - 0.026 13.5 0.2 0.047 12.7 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Arm PF00514.18 KUM62404.1 - 0.12 12.1 21.1 5.2 7.0 0.3 7.3 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat TPR_16 PF13432.1 KUM62404.1 - 3 8.6 12.7 3 8.6 0.5 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_28 PF00295.12 KUM62405.1 - 1.3e-113 379.2 18.6 1.5e-113 379.0 12.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 KUM62405.1 - 0.011 15.4 26.7 0.012 15.3 13.8 3.0 1 1 1 2 2 2 0 Right handed beta helix region MFS_1 PF07690.11 KUM62406.1 - 1.4e-30 106.2 26.2 1.9e-30 105.8 18.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM62406.1 - 0.0017 16.6 2.0 0.0017 16.6 1.4 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) COPIIcoated_ERV PF07970.7 KUM62407.1 - 9.2e-69 231.4 0.0 4.7e-45 153.9 0.0 2.3 1 1 1 2 2 2 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KUM62407.1 - 3.4e-34 116.7 0.0 6.2e-34 115.8 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) TAP_C PF03943.8 KUM62408.1 - 8.5e-12 44.3 0.8 1.5e-11 43.4 0.6 1.4 1 0 0 1 1 1 1 TAP C-terminal domain NTF2 PF02136.15 KUM62408.1 - 2.2e-08 34.4 0.0 4e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_4 PF12799.2 KUM62408.1 - 3.9e-07 29.5 3.3 3.2e-05 23.4 0.1 2.8 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KUM62408.1 - 0.0009 18.9 0.0 0.0026 17.4 0.0 1.9 1 0 0 1 1 1 1 Leucine rich repeat LRR_6 PF13516.1 KUM62408.1 - 0.057 13.5 0.1 12 6.2 0.0 3.1 2 0 0 2 2 2 0 Leucine Rich repeat LRR_1 PF00560.28 KUM62408.1 - 0.057 13.4 0.1 28 5.2 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich Repeat Vps53_N PF04100.7 KUM62409.1 - 2.1e-107 359.2 3.0 2.1e-107 359.2 2.1 1.6 2 0 0 2 2 2 1 Vps53-like, N-terminal DUF2450 PF10475.4 KUM62409.1 - 3.5e-06 26.1 7.1 7.3e-06 25.0 4.9 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) RINT1_TIP1 PF04437.8 KUM62409.1 - 5.1e-05 22.0 4.8 0.00012 20.8 0.2 2.9 2 1 0 2 2 2 1 RINT-1 / TIP-1 family Spc7 PF08317.6 KUM62409.1 - 0.0026 16.4 5.3 0.0046 15.6 3.7 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein COG2 PF06148.6 KUM62409.1 - 0.0036 17.1 2.9 0.0036 17.1 2.0 2.4 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2451 PF10474.4 KUM62409.1 - 0.013 15.2 0.5 0.049 13.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2451) Zw10 PF06248.8 KUM62409.1 - 0.063 11.4 7.7 0.037 12.1 3.6 1.8 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 MFS_1 PF07690.11 KUM62410.1 - 4.3e-11 42.1 36.1 1.5e-08 33.7 14.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KUM62410.1 - 0.0071 14.4 2.4 0.0084 14.2 0.0 2.0 1 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Abhydrolase_6 PF12697.2 KUM62412.1 - 3.5e-30 105.5 0.5 4.4e-30 105.2 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM62412.1 - 3e-10 40.0 0.7 7.9e-10 38.6 0.5 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KUM62412.1 - 0.099 12.2 0.0 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein Ank_2 PF12796.2 KUM62415.1 - 1.4e-06 28.5 0.0 0.00012 22.3 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 KUM62415.1 - 6.1e-05 22.6 0.0 0.95 9.3 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KUM62415.1 - 0.00082 19.8 0.0 0.88 10.1 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM62415.1 - 0.015 15.4 0.0 30 5.2 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.1 KUM62415.1 - 0.081 13.2 0.1 54 4.2 0.0 3.4 2 1 1 3 3 3 0 Ankyrin repeats (many copies) FGGY_N PF00370.16 KUM62415.1 - 0.081 12.2 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Ank_2 PF12796.2 KUM62416.1 - 1.4e-209 679.1 67.8 1.3e-20 73.5 0.2 15.1 2 2 18 20 20 20 20 Ankyrin repeats (3 copies) Ank PF00023.25 KUM62416.1 - 1.5e-123 396.9 64.7 1.2e-07 31.1 0.0 30.1 30 0 0 30 30 30 26 Ankyrin repeat Ank_4 PF13637.1 KUM62416.1 - 1.3e-109 356.8 32.2 1.8e-09 37.8 0.0 22.1 13 5 9 22 22 22 20 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM62416.1 - 3.4e-101 329.0 49.4 1.9e-10 40.6 0.3 24.3 8 6 17 26 26 26 23 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM62416.1 - 7.4e-97 307.4 40.9 2.6e-06 27.1 0.0 30.2 31 0 0 31 31 31 25 Ankyrin repeat SPRY PF00622.23 KUM62416.1 - 4.8e-16 58.9 0.1 9.3e-16 58.0 0.1 1.4 1 0 0 1 1 1 1 SPRY domain THAP PF05485.7 KUM62416.1 - 0.19 11.9 0.5 0.36 11.0 0.4 1.4 1 0 0 1 1 1 0 THAP domain DnaJ PF00226.26 KUM62418.1 - 5e-25 87.0 1.7 9.6e-25 86.1 1.2 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KUM62418.1 - 1.7e-20 72.6 0.3 1.6e-17 63.1 0.0 2.7 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KUM62418.1 - 6e-13 48.6 19.3 1.1e-12 47.8 13.4 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KUM62418.1 - 0.098 12.3 9.5 0.078 12.6 1.6 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF2614 PF11023.3 KUM62418.1 - 6.9 6.4 5.3 4.5 7.0 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) dCMP_cyt_deam_1 PF00383.17 KUM62419.1 - 3.5e-23 81.2 0.0 4.5e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 KUM62419.1 - 6.8e-06 25.9 2.0 0.056 13.2 0.4 2.2 1 1 1 2 2 2 2 Bd3614-like deaminase XOO_2897-deam PF14440.1 KUM62419.1 - 0.005 16.5 0.0 0.008 15.8 0.0 1.4 1 1 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase APOBEC_N PF08210.6 KUM62419.1 - 0.051 13.2 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain Peptidase_C41 PF05417.6 KUM62419.1 - 0.11 12.0 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Hepatitis E cysteine protease URO-D PF01208.12 KUM62420.1 - 4.6e-122 407.2 0.0 5.2e-122 407.0 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PP1 PF07430.6 KUM62420.1 - 0.043 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Phloem filament protein PP1 WD40 PF00400.27 KUM62421.1 - 3.3e-07 29.9 0.3 9.7e-05 22.1 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat CPSF_A PF03178.10 KUM62421.1 - 0.0016 17.6 0.0 0.007 15.4 0.0 2.0 3 0 0 3 3 3 1 CPSF A subunit region Ribosomal_L10 PF00466.15 KUM62422.1 - 1.6e-24 85.6 0.0 3e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 KUM62422.1 - 9.2e-19 67.6 1.5 9.2e-19 67.6 1.1 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein Sulfate_transp PF00916.15 KUM62423.1 - 6.7e-77 258.2 9.4 6.7e-77 258.2 6.5 1.6 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KUM62423.1 - 1e-30 105.2 3.6 1e-30 105.2 2.5 3.3 5 0 0 5 5 5 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KUM62423.1 - 3e-08 33.0 0.0 5.2e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 STAS domain SNN_transmemb PF09049.5 KUM62423.1 - 2.2 8.0 10.5 0.031 13.9 1.2 2.5 2 0 0 2 2 2 0 Stannin transmembrane Peptidase_S8 PF00082.17 KUM62424.1 - 3.4e-19 69.0 0.0 6.7e-19 68.1 0.0 1.4 1 1 0 1 1 1 1 Subtilase family PilO PF04350.8 KUM62424.1 - 0.072 12.9 0.1 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 Pilus assembly protein, PilO TroA PF01297.12 KUM62424.1 - 0.091 11.9 0.2 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Periplasmic solute binding protein family PH PF00169.24 KUM62425.1 - 5.2e-05 23.3 0.0 0.00033 20.7 0.0 2.3 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 KUM62425.1 - 0.071 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain MFS_1 PF07690.11 KUM62426.1 - 4.3e-05 22.4 2.3 4.5e-05 22.3 1.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily RNA_pol_Rpb6 PF01192.17 KUM62427.1 - 4.8e-24 83.8 0.2 8.3e-24 83.0 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 KOW PF00467.24 KUM62427.1 - 0.0032 17.1 0.0 0.0051 16.4 0.0 1.4 1 0 0 1 1 1 1 KOW motif DUF2163 PF09931.4 KUM62428.1 - 0.15 11.7 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2163) zf-C2H2 PF00096.21 KUM62430.1 - 1.4e-29 100.5 50.9 0.00032 20.8 0.0 11.0 11 0 0 11 11 11 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KUM62430.1 - 6.3e-26 88.7 48.0 0.0023 18.1 0.1 10.5 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KUM62430.1 - 5e-21 73.8 57.5 1.2e-05 25.3 0.2 11.4 11 0 0 11 11 11 7 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KUM62430.1 - 0.00065 19.7 20.7 1.2 9.4 0.0 8.1 10 0 0 10 10 10 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KUM62430.1 - 0.00085 19.4 9.5 1.2 9.3 0.0 6.8 8 0 0 8 8 8 1 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 KUM62430.1 - 0.0057 16.8 0.1 0.0057 16.8 0.0 10.4 11 0 0 11 11 11 2 C2H2-type zinc-finger domain GAGA PF09237.6 KUM62430.1 - 0.98 9.0 12.3 0.037 13.6 0.9 3.6 4 0 0 4 4 4 0 GAGA factor zf-LYAR PF08790.6 KUM62430.1 - 4.3 7.1 7.4 34 4.2 0.3 4.7 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger MFS_1 PF07690.11 KUM62433.1 - 2.1e-20 72.7 52.0 2.7e-14 52.6 23.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_1 PF00583.19 KUM62434.1 - 1.5e-11 44.1 0.1 2.1e-11 43.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KUM62434.1 - 2.7e-06 27.0 0.0 4.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KUM62434.1 - 0.0028 17.7 0.0 0.0041 17.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KUM62434.1 - 0.0071 16.4 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KUM62434.1 - 0.023 14.5 0.1 0.045 13.6 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KUM62434.1 - 0.043 13.6 0.0 0.066 13.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 KUM62435.1 - 1e-15 57.3 28.6 1.3e-15 56.9 19.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM62435.1 - 1.5 7.3 18.6 2.4 6.6 12.9 1.4 1 1 0 1 1 1 0 Sugar (and other) transporter HNH_2 PF13391.1 KUM62436.1 - 7.4e-08 32.0 0.1 1.5e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease Pantoate_transf PF02548.10 KUM62437.1 - 7.2e-104 346.5 1.1 8.4e-104 346.3 0.7 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 KUM62437.1 - 6.5e-09 35.3 1.2 2.6e-08 33.4 0.8 1.8 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Mg_chelatase_2 PF13335.1 KUM62437.1 - 0.14 12.5 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NanE PF04131.9 KUM62437.1 - 0.18 10.7 1.7 5.9 5.8 0.1 2.7 2 1 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase Ribosomal_S7 PF00177.16 KUM62439.1 - 3e-24 85.2 0.0 7.4e-24 84.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e ICL PF00463.16 KUM62439.1 - 0.14 10.3 0.1 0.21 9.7 0.1 1.2 1 0 0 1 1 1 0 Isocitrate lyase family CDC27 PF09507.5 KUM62440.1 - 6.8 5.7 33.2 8.5 5.4 23.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SPX PF03105.14 KUM62441.1 - 6.9e-50 170.3 0.0 1.2e-49 169.6 0.0 1.4 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 KUM62441.1 - 1.8e-30 106.2 40.3 2.6e-30 105.7 27.9 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 KUM62441.1 - 1.4e-14 53.4 46.8 3.6e-13 48.8 17.0 2.2 1 1 1 2 2 2 2 Citrate transporter MEDS PF14417.1 KUM62441.1 - 0.01 14.8 0.2 0.12 11.4 0.1 2.2 2 0 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain DUF2470 PF10615.4 KUM62442.1 - 3.7e-17 62.3 0.1 5.3e-17 61.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) PBP1_TM PF14812.1 KUM62443.1 - 4 7.8 21.2 0.78 10.0 4.0 2.3 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_S8e PF01201.17 KUM62445.1 - 6.1e-47 159.0 1.2 7.1e-47 158.8 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Glyco_hydro_81 PF03639.8 KUM62446.1 - 4.4e-202 672.8 6.7 5.5e-202 672.5 4.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 DUF1180 PF06679.7 KUM62446.1 - 8.8 6.1 6.7 18 5.1 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Metallophos_2 PF12850.2 KUM62447.1 - 3.6e-11 43.1 0.0 1.1e-10 41.5 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KUM62447.1 - 1.5e-10 40.8 0.4 3.4e-09 36.3 0.3 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase HECT PF00632.20 KUM62448.1 - 4.2e-74 249.5 0.0 5.6e-74 249.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DAO PF01266.19 KUM62449.1 - 1.6e-51 175.3 0.8 2.2e-51 174.8 0.6 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase MAPEG PF01124.13 KUM62449.1 - 2.4e-16 59.4 2.2 4.7e-16 58.5 1.5 1.4 1 0 0 1 1 1 1 MAPEG family NAD_binding_8 PF13450.1 KUM62449.1 - 4.4e-06 26.6 0.2 1.5e-05 24.8 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KUM62449.1 - 6.9e-05 23.0 0.1 0.00015 21.9 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KUM62449.1 - 0.00028 20.0 0.3 0.02 13.9 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 KUM62449.1 - 0.0067 15.5 3.2 0.055 12.5 2.2 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KUM62449.1 - 0.0075 15.3 0.1 0.027 13.5 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 KUM62449.1 - 0.013 15.8 0.2 0.34 11.3 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KUM62449.1 - 0.027 14.3 0.1 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KUM62449.1 - 0.14 10.6 0.1 0.82 8.0 0.1 2.1 2 1 1 3 3 3 0 HI0933-like protein NAD_binding_9 PF13454.1 KUM62449.1 - 0.14 11.8 0.3 0.55 10.0 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding zf-RING_2 PF13639.1 KUM62453.1 - 5.6e-10 38.8 9.0 9.8e-10 38.1 6.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KUM62453.1 - 0.0012 18.5 8.2 0.0021 17.6 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF912 PF06024.7 KUM62453.1 - 0.0014 18.6 0.0 0.0035 17.3 0.0 1.6 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) zf-RING_5 PF14634.1 KUM62453.1 - 0.0048 16.5 7.9 0.0091 15.7 5.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KUM62453.1 - 0.0051 16.8 10.3 0.0089 16.0 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1191 PF06697.7 KUM62453.1 - 0.0098 14.7 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) zf-C3HC4_3 PF13920.1 KUM62453.1 - 0.032 13.8 6.9 0.058 13.0 4.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KUM62453.1 - 0.039 14.0 7.0 0.11 12.5 4.9 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger TMEM154 PF15102.1 KUM62453.1 - 0.062 13.0 0.2 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 TMEM154 protein family AA_permease_2 PF13520.1 KUM62453.1 - 0.063 11.8 0.1 0.088 11.3 0.0 1.1 1 0 0 1 1 1 0 Amino acid permease Rifin_STEVOR PF02009.11 KUM62453.1 - 0.075 12.6 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Rifin/stevor family zf-Nse PF11789.3 KUM62453.1 - 0.8 9.2 4.9 1.6 8.2 3.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Ribosomal_L15e PF00827.12 KUM62454.1 - 2.3e-88 294.7 14.0 2.8e-88 294.4 9.7 1.0 1 0 0 1 1 1 1 Ribosomal L15 Fungal_trans PF04082.13 KUM62455.1 - 7.8e-13 47.8 1.3 2.5e-12 46.2 0.1 2.2 1 1 1 2 2 2 1 Fungal specific transcription factor domain RAI16-like PF10257.4 KUM62455.1 - 0.081 11.8 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Retinoic acid induced 16-like protein WD40 PF00400.27 KUM62457.1 - 5.7e-56 184.5 25.3 7.9e-15 54.0 0.0 9.0 9 1 0 9 9 9 6 WD domain, G-beta repeat Pkinase PF00069.20 KUM62457.1 - 9e-52 175.7 0.0 1.4e-51 175.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM62457.1 - 3.3e-24 85.3 0.0 4.7e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase eIF2A PF08662.6 KUM62457.1 - 5.5e-09 36.0 0.1 0.0021 17.8 0.0 3.7 2 1 2 4 4 4 4 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.4 KUM62457.1 - 2.4e-08 33.1 6.1 3.2 7.1 0.0 7.2 8 0 0 8 8 8 3 Proteasome subunit A N-terminal signature Nup160 PF11715.3 KUM62457.1 - 1.6e-05 23.2 8.8 0.12 10.4 0.1 5.1 2 2 1 4 4 4 2 Nucleoporin Nup120/160 PD40 PF07676.7 KUM62457.1 - 2.1e-05 24.0 4.3 49 3.7 0.0 7.2 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 KUM62457.1 - 0.00012 20.5 0.0 0.015 13.6 0.0 2.5 2 0 0 2 2 2 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 KUM62457.1 - 0.0017 17.8 3.5 0.79 9.1 0.1 3.4 1 1 0 2 2 2 2 PQQ-like domain Kdo PF06293.9 KUM62457.1 - 0.0044 16.1 0.0 0.0085 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family IKI3 PF04762.7 KUM62457.1 - 0.088 10.6 0.0 2.2 5.9 0.0 2.3 2 0 0 2 2 2 0 IKI3 family TruB_C PF09142.6 KUM62457.1 - 0.11 12.1 0.0 80 2.9 0.0 4.0 4 0 0 4 4 4 0 tRNA Pseudouridine synthase II, C terminal Iso_dh PF00180.15 KUM62458.1 - 1.5e-88 297.1 0.0 1.8e-88 296.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Fungal_trans PF04082.13 KUM62459.1 - 1.5e-21 76.4 0.0 3e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_8 PF13450.1 KUM62460.1 - 1.7e-09 37.5 0.0 3.5e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KUM62460.1 - 6.7e-06 26.3 0.0 1.1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase D-aminoacyl_C PF07908.7 KUM62460.1 - 0.082 12.2 0.0 12 5.3 0.0 2.7 2 0 0 2 2 2 0 D-aminoacylase, C-terminal region NAD_binding_9 PF13454.1 KUM62460.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding HECT PF00632.20 KUM62461.1 - 1.5e-81 274.0 0.0 3e-81 273.0 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF983 PF06170.7 KUM62462.1 - 7.1 6.8 8.4 12 6.1 5.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF983) Utp14 PF04615.8 KUM62463.1 - 1.8e-219 730.6 80.1 1.8e-219 730.6 55.5 2.1 1 1 1 2 2 2 1 Utp14 protein Ribosomal_L14e PF01929.12 KUM62464.1 - 0.0048 17.2 0.1 0.0099 16.2 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L14 MRP-L27 PF09809.4 KUM62464.1 - 0.077 12.6 0.3 0.19 11.3 0.2 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L27 DUF4085 PF13315.1 KUM62464.1 - 0.092 12.1 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) RRM_1 PF00076.17 KUM62465.1 - 2.1e-77 254.7 6.9 2.9e-19 68.4 0.2 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM62465.1 - 3.1e-48 161.6 1.7 7.9e-12 44.9 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM62465.1 - 6.5e-37 125.1 0.7 3.2e-08 33.3 0.1 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 KUM62465.1 - 1.3e-31 108.0 0.9 6.1e-31 105.9 0.5 2.2 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 KUM62465.1 - 1.6e-06 27.7 0.2 2.6 7.9 0.0 4.3 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 KUM62465.1 - 0.00025 21.1 0.9 1.1 9.5 0.0 3.9 3 1 1 4 4 4 2 Cobalamin biosynthesis central region Limkain-b1 PF11608.3 KUM62465.1 - 0.0028 17.3 5.7 0.12 12.1 0.2 3.6 3 0 0 3 3 3 1 Limkain b1 CSD PF00313.17 KUM62465.1 - 0.033 13.9 2.7 26 4.6 0.0 3.6 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 KUM62465.1 - 0.055 12.9 3.0 6.3 6.3 0.0 3.6 3 0 0 3 3 3 0 Ribonuclease B OB domain SOBP PF15279.1 KUM62465.1 - 0.39 11.0 8.7 0.69 10.2 6.0 1.5 1 0 0 1 1 1 0 Sine oculis-binding protein Fungal_trans PF04082.13 KUM62466.1 - 5.7e-24 84.3 0.9 5.7e-24 84.3 0.7 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF2451 PF10474.4 KUM62467.1 - 0.098 12.3 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) DUF1656 PF07869.7 KUM62469.1 - 0.22 11.3 0.9 0.41 10.4 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) Ada3 PF10198.4 KUM62470.1 - 1.1e-39 135.1 0.1 3.5e-39 133.5 0.0 1.9 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 NPR2 PF06218.6 KUM62471.1 - 3e-130 434.7 0.0 4.6e-130 434.1 0.0 1.2 1 0 0 1 1 1 1 Nitrogen permease regulator 2 Amidohydro_1 PF01979.15 KUM62472.1 - 4.6e-62 210.5 3.5 8.1e-62 209.7 1.2 2.1 2 0 0 2 2 2 1 Amidohydrolase family Urease_alpha PF00449.15 KUM62472.1 - 3.7e-56 188.4 1.3 5.1e-56 188.0 0.4 1.7 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.13 KUM62472.1 - 8e-37 125.2 0.1 1.7e-36 124.1 0.1 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.15 KUM62472.1 - 3e-36 123.2 0.1 8e-29 99.4 0.0 3.0 2 1 1 3 3 3 2 Urease beta subunit Amidohydro_5 PF13594.1 KUM62472.1 - 2.4e-07 30.4 4.1 6.6e-07 29.0 2.9 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KUM62472.1 - 4.3e-07 29.4 0.6 0.00016 20.9 0.0 2.9 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_4 PF13147.1 KUM62472.1 - 0.012 15.6 0.3 1.7 8.6 0.0 2.7 3 0 0 3 3 3 0 Amidohydrolase Lyase_8_C PF02884.12 KUM62472.1 - 0.18 11.8 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide lyase family 8, C-terminal beta-sandwich domain HMG_box PF00505.14 KUM62473.1 - 6e-11 42.4 1.5 1.2e-10 41.5 1.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KUM62473.1 - 6.5e-07 29.6 3.1 1.7e-06 28.2 1.7 2.1 2 0 0 2 2 2 1 HMG-box domain Herpes_pp85 PF04637.7 KUM62473.1 - 0.16 10.2 4.5 0.22 9.7 3.1 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DRMBL PF07522.9 KUM62474.1 - 4.2e-07 29.9 0.1 1.4e-06 28.2 0.1 1.9 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 KUM62474.1 - 3.3e-05 23.5 0.0 8.1e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Use1 PF09753.4 KUM62474.1 - 1.3 8.3 4.7 2.7 7.3 3.2 1.4 1 0 0 1 1 1 0 Membrane fusion protein Use1 ABC2_membrane PF01061.19 KUM62476.1 - 2e-17 63.0 11.8 2.1e-17 62.9 8.2 1.0 1 0 0 1 1 1 1 ABC-2 type transporter P5-ATPase PF12409.3 KUM62476.1 - 0.00023 21.0 1.3 0.00023 21.0 0.9 1.8 1 1 2 3 3 3 1 P5-type ATPase cation transporter ABC2_membrane_3 PF12698.2 KUM62476.1 - 0.05 12.6 11.3 0.057 12.4 7.9 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane_4 PF12730.2 KUM62476.1 - 0.19 10.8 14.3 0.23 10.5 9.9 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein AgrB PF04647.10 KUM62476.1 - 1.9 7.4 9.4 2.6 7.0 6.5 1.1 1 0 0 1 1 1 0 Accessory gene regulator B Zn_clus PF00172.13 KUM62477.1 - 2e-09 37.2 9.7 3e-09 36.6 6.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KUM62478.1 - 7.2e-09 34.8 0.1 1.1e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM62478.1 - 1.4e-06 28.0 9.7 2.7e-06 27.1 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.23 KUM62479.1 - 2.4e-64 217.3 0.0 5.3e-64 216.1 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.1 KUM62479.1 - 0.0011 19.8 0.0 0.0022 18.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TPR_11 PF13414.1 KUM62480.1 - 7.1e-09 35.2 5.6 6.3e-05 22.5 0.1 4.2 3 1 1 4 4 4 2 TPR repeat TPR_2 PF07719.12 KUM62480.1 - 2e-08 33.5 7.6 0.0021 17.8 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 KUM62480.1 - 3.6e-06 27.4 1.8 0.38 11.4 0.0 4.9 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KUM62480.1 - 6.9e-06 25.9 3.7 0.0031 17.4 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KUM62480.1 - 1.2e-05 24.6 3.8 0.041 13.5 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.9 KUM62480.1 - 0.057 13.8 0.7 13 6.5 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 KUM62480.1 - 0.27 11.5 8.1 2.7 8.3 0.1 4.4 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 KUM62480.1 - 0.52 11.0 9.0 11 6.9 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Fungal_trans PF04082.13 KUM62481.1 - 1.3e-24 86.4 1.8 1.3e-24 86.4 1.2 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain NACHT PF05729.7 KUM62482.1 - 3.4e-11 43.0 0.1 7.9e-11 41.8 0.1 1.6 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.15 KUM62482.1 - 1.1e-10 40.9 0.0 3.2e-10 39.3 0.0 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_22 PF13401.1 KUM62482.1 - 5.1e-08 33.1 0.0 1.3e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KUM62482.1 - 2e-05 24.6 0.0 6.4e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KUM62482.1 - 8.9e-05 23.2 0.0 0.00032 21.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KUM62482.1 - 0.00096 19.4 0.0 0.0033 17.7 0.0 1.9 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.22 KUM62482.1 - 0.0027 17.9 0.0 0.0055 17.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 KUM62482.1 - 0.032 13.7 0.2 0.084 12.4 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain KAP_NTPase PF07693.9 KUM62482.1 - 0.047 12.6 0.7 1.4 7.8 0.0 2.2 1 1 0 2 2 2 0 KAP family P-loop domain RNA_helicase PF00910.17 KUM62482.1 - 0.063 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 KUM62482.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain UPF0079 PF02367.12 KUM62482.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 KUM62482.1 - 0.13 11.4 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 KUM62482.1 - 0.21 10.6 0.0 0.53 9.3 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.1 KUM62482.1 - 0.25 10.9 0.0 0.47 10.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KUM62482.1 - 0.4 10.3 0.0 0.78 9.4 0.0 1.4 1 0 0 1 1 1 0 NTPase RNA_pol_Rpc34 PF05158.7 KUM62483.1 - 4.3e-117 390.9 0.0 4.8e-117 390.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit MarR PF01047.17 KUM62483.1 - 0.07 12.8 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 MarR family TrmB PF01978.14 KUM62483.1 - 0.085 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB PadR PF03551.9 KUM62483.1 - 0.13 12.0 0.1 0.62 9.8 0.0 2.1 1 1 1 2 2 2 0 Transcriptional regulator PadR-like family TPR_11 PF13414.1 KUM62484.1 - 1.4e-56 187.9 23.1 9.9e-19 66.7 1.7 6.3 5 1 2 7 7 7 7 TPR repeat TPR_1 PF00515.23 KUM62484.1 - 2.4e-44 147.1 22.5 6.1e-06 25.6 0.0 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 KUM62484.1 - 1.6e-34 115.0 22.2 4.5e-05 23.0 0.1 9.4 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 KUM62484.1 - 1.9e-22 79.3 13.2 5e-06 27.0 0.1 6.6 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 KUM62484.1 - 1.1e-21 76.5 18.8 1.1e-08 34.8 0.1 5.9 3 3 3 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 KUM62484.1 - 1.1e-15 56.7 12.4 0.12 13.0 0.0 8.8 4 3 6 10 10 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 KUM62484.1 - 1.1e-12 46.7 18.8 0.00032 20.2 0.1 7.4 6 2 2 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 KUM62484.1 - 2.7e-11 42.7 6.8 0.028 14.6 0.1 7.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KUM62484.1 - 4.2e-11 43.0 16.7 0.0018 18.5 0.2 6.6 4 3 2 7 7 6 4 Tetratricopeptide repeat TPR_9 PF13371.1 KUM62484.1 - 5.7e-09 35.7 7.9 0.013 15.3 0.0 5.3 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 KUM62484.1 - 1.4e-08 33.8 11.8 0.025 14.3 0.0 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KUM62484.1 - 1.9e-08 34.0 0.7 0.064 13.1 0.0 4.7 4 0 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.1 KUM62484.1 - 0.00034 20.6 0.4 0.00034 20.6 0.3 5.1 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 KUM62484.1 - 0.0012 19.1 18.7 4.8 7.8 0.0 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_3 PF07720.7 KUM62484.1 - 0.032 14.0 10.5 2.2 8.1 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Inhibitor_I9 PF05922.11 KUM62484.1 - 0.051 14.1 0.1 0.34 11.5 0.0 2.4 2 0 0 2 2 2 0 Peptidase inhibitor I9 PPR PF01535.15 KUM62484.1 - 0.065 13.2 0.8 27 5.0 0.0 4.1 4 0 0 4 4 3 0 PPR repeat TPR_10 PF13374.1 KUM62484.1 - 0.26 11.2 9.0 6.3 6.8 0.1 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat RPN7 PF10602.4 KUM62484.1 - 0.4 10.0 14.9 5.7 6.2 0.0 5.3 4 2 1 5 5 5 0 26S proteasome subunit RPN7 DUF2937 PF11157.3 KUM62484.1 - 0.72 9.1 5.5 0.85 8.9 2.9 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF2937) MIT PF04212.13 KUM62484.1 - 1.6 8.6 20.6 0.79 9.6 0.9 5.9 5 1 1 6 6 5 0 MIT (microtubule interacting and transport) domain PXT1 PF15214.1 KUM62487.1 - 0.063 13.5 0.9 0.11 12.7 0.6 1.4 1 0 0 1 1 1 0 Peroxisomal testis-specific protein 1 ING PF12998.2 KUM62488.1 - 2.8e-25 88.6 3.8 4.5e-25 87.9 2.6 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KUM62488.1 - 2.9e-08 33.2 9.8 5e-08 32.5 6.8 1.4 1 0 0 1 1 1 1 PHD-finger TFIIA PF03153.8 KUM62488.1 - 0.00053 20.0 9.3 0.00053 20.0 6.4 1.5 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF4200 PF13863.1 KUM62488.1 - 0.0058 16.5 1.4 0.16 11.9 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) Cwf_Cwc_15 PF04889.7 KUM62488.1 - 0.06 13.0 5.6 0.12 12.0 3.9 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PHD_2 PF13831.1 KUM62488.1 - 0.91 8.8 5.3 1.8 7.9 3.6 1.5 1 0 0 1 1 1 0 PHD-finger Nop14 PF04147.7 KUM62488.1 - 1.4 6.7 7.9 2.5 5.9 5.5 1.4 1 0 0 1 1 1 0 Nop14-like family FSH1 PF03959.8 KUM62492.1 - 4.5e-20 72.0 0.0 5.1e-20 71.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Methyltransf_23 PF13489.1 KUM62493.1 - 0.00017 21.3 0.0 0.00035 20.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain ketoacyl-synt PF00109.21 KUM62494.1 - 5.3e-69 232.5 0.0 1e-68 231.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KUM62494.1 - 1.7e-50 171.1 0.0 4.8e-50 169.7 0.0 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 KUM62494.1 - 1.9e-46 158.5 0.0 3.1e-46 157.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KUM62494.1 - 3.9e-44 151.2 0.0 5.9e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KUM62494.1 - 3.5e-38 130.0 0.0 1.1e-37 128.5 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 KUM62494.1 - 7.9e-38 129.9 0.0 1.8e-37 128.8 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_12 PF08242.7 KUM62494.1 - 3.3e-18 65.9 0.0 1.6e-17 63.8 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM62494.1 - 3.6e-15 56.0 0.0 1.4e-14 54.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM62494.1 - 4e-11 42.7 0.0 1.2e-10 41.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KUM62494.1 - 6.4e-11 41.9 0.0 1.7e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KUM62494.1 - 2e-09 38.0 0.0 1e-07 32.5 0.0 3.7 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM62494.1 - 1.3e-08 35.2 0.0 4.1e-08 33.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KUM62494.1 - 2.3e-05 23.6 0.0 6.7e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Polysacc_synt_2 PF02719.10 KUM62494.1 - 0.00038 19.4 0.0 0.00061 18.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KUM62494.1 - 0.00053 18.7 0.0 0.00088 18.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KUM62494.1 - 0.00072 19.0 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.18 KUM62494.1 - 0.0015 17.5 0.0 0.0028 16.6 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain NmrA PF05368.8 KUM62494.1 - 0.0016 17.7 0.0 0.0033 16.7 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family ACP_syn_III PF08545.5 KUM62494.1 - 0.0079 15.8 0.2 0.034 13.8 0.2 2.1 2 0 0 2 2 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III F420_oxidored PF03807.12 KUM62494.1 - 0.033 14.6 0.2 0.85 10.0 0.1 2.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent PCMT PF01135.14 KUM62494.1 - 0.051 13.1 0.0 5.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Shikimate_DH PF01488.15 KUM62494.1 - 0.064 13.3 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Methyltransf_16 PF10294.4 KUM62494.1 - 0.081 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase PP-binding PF00550.20 KUM62494.1 - 0.085 13.1 0.0 0.24 11.6 0.0 1.9 1 0 0 1 1 1 0 Phosphopantetheine attachment site ADH_N PF08240.7 KUM62494.1 - 0.16 11.7 0.3 0.63 9.8 0.0 2.1 2 0 0 2 2 1 0 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 KUM62495.1 - 1.5e-56 191.3 0.8 2e-56 190.9 0.6 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KUM62495.1 - 9.5e-14 50.8 2.5 1.2e-13 50.5 0.2 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KUM62495.1 - 0.0074 15.7 0.5 0.0074 15.7 0.3 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain RNA_pol_Rpb2_6 PF00562.23 KUM62496.1 - 1.1e-123 412.7 0.1 2.1e-123 411.8 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KUM62496.1 - 1.8e-61 206.6 0.0 2.9e-61 205.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KUM62496.1 - 9.3e-46 155.6 0.0 1.5e-45 154.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 KUM62496.1 - 1.7e-30 105.0 0.0 3.8e-30 103.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 KUM62496.1 - 4.8e-24 83.9 1.2 1.1e-23 82.8 0.8 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 KUM62496.1 - 5.4e-23 80.5 0.2 2.3e-22 78.4 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 KUM62496.1 - 1e-22 79.8 0.1 2.2e-22 78.7 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 CTNNBL PF08216.6 KUM62497.1 - 4.1e-36 122.8 1.0 7.9e-35 118.7 0.2 2.7 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.18 KUM62497.1 - 0.0043 16.8 0.0 5.3 7.0 0.0 3.5 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KUM62497.1 - 0.0073 16.5 4.8 0.5 10.6 0.1 3.8 2 1 1 3 3 3 1 HEAT repeats Mo25 PF08569.6 KUM62497.1 - 0.022 13.8 0.4 0.062 12.3 0.1 1.8 1 1 0 1 1 1 0 Mo25-like DUF913 PF06025.7 KUM62497.1 - 0.031 13.0 0.2 0.45 9.2 0.1 2.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF913) Drf_GBD PF06371.8 KUM62497.1 - 0.077 12.3 0.3 0.4 10.0 0.0 2.2 1 1 0 2 2 2 0 Diaphanous GTPase-binding Domain Utp13 PF08625.6 KUM62497.1 - 0.19 11.3 1.4 5.8 6.5 0.0 3.1 3 0 0 3 3 3 0 Utp13 specific WD40 associated domain DUF1471 PF07338.8 KUM62499.1 - 0.016 14.8 0.0 0.037 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) C2 PF00168.25 KUM62500.1 - 5.6e-66 218.4 2.2 9.9e-20 70.1 0.0 5.6 5 0 0 5 5 5 5 C2 domain NT-C2 PF10358.4 KUM62500.1 - 0.00089 18.7 0.0 0.86 9.0 0.0 2.6 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins DUF2404 PF10296.4 KUM62500.1 - 0.15 12.2 0.6 1.3 9.2 0.0 2.8 4 0 0 4 4 4 0 Putative integral membrane protein conserved region (DUF2404) B56 PF01603.15 KUM62500.1 - 0.19 10.3 0.0 0.28 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) UDPGP PF01704.13 KUM62501.1 - 5.3e-184 611.5 0.3 6.1e-184 611.3 0.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PilO PF04350.8 KUM62501.1 - 0.0067 16.3 0.1 0.02 14.8 0.0 1.7 2 0 0 2 2 2 1 Pilus assembly protein, PilO AT_hook PF02178.14 KUM62502.1 - 0.0025 17.3 32.9 0.029 14.0 2.0 4.1 4 0 0 4 4 4 3 AT hook motif AP_endonuc_2 PF01261.19 KUM62503.1 - 4.3e-22 78.4 0.0 5.9e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel MFS_1 PF07690.11 KUM62504.1 - 3.8e-11 42.3 8.2 1.6e-10 40.2 6.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.11 KUM62504.1 - 0.00028 19.7 1.3 0.00035 19.4 0.9 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter Sugar_tr PF00083.19 KUM62504.1 - 0.018 13.6 3.0 0.048 12.2 2.0 1.7 1 1 0 1 1 1 0 Sugar (and other) transporter Imp-YgjV PF10688.4 KUM62504.1 - 0.023 14.1 0.6 0.051 13.0 0.4 1.5 1 0 0 1 1 1 0 Bacterial inner membrane protein His_Phos_1 PF00300.17 KUM62506.1 - 2.7e-14 53.5 0.2 8.5e-14 51.9 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Glyco_hydro_3 PF00933.16 KUM62507.1 - 2.1e-90 302.7 0.0 2.9e-90 302.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KUM62507.1 - 2.9e-54 183.9 1.2 4e-53 180.2 0.3 2.5 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KUM62507.1 - 2.1e-19 69.1 0.1 3.7e-19 68.4 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain MFS_1 PF07690.11 KUM62508.1 - 1e-42 146.1 57.5 1e-42 146.1 39.8 2.9 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM62508.1 - 3.4e-14 52.2 19.4 3.4e-14 52.2 13.4 2.8 3 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 KUM62508.1 - 1.2e-12 46.8 31.1 1.8e-12 46.2 21.3 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF21 PF01595.15 KUM62509.1 - 4e-32 110.9 0.1 6.5e-32 110.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 KUM62509.1 - 3.5e-06 26.6 0.4 0.014 15.1 0.0 2.9 2 0 0 2 2 2 2 CBS domain AhpC-TSA PF00578.16 KUM62511.1 - 1.2e-32 112.2 0.0 1.5e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 KUM62511.1 - 2.9e-13 49.2 0.2 4.7e-13 48.5 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 KUM62511.1 - 7.2e-13 48.3 0.0 9.3e-13 47.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin Methyltransf_23 PF13489.1 KUM62512.1 - 5.7e-10 39.1 0.0 8e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM62512.1 - 5e-06 26.9 0.0 2.9e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM62512.1 - 0.00062 19.3 0.0 0.0013 18.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM62512.1 - 0.00091 19.7 0.0 0.0031 18.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM62512.1 - 0.0047 17.3 0.0 0.018 15.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM62512.1 - 0.012 15.9 0.0 0.046 14.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_PK PF05891.7 KUM62512.1 - 0.12 11.6 0.0 0.38 10.0 0.0 1.8 2 1 0 2 2 2 0 AdoMet dependent proline di-methyltransferase IncA PF04156.9 KUM62513.1 - 0.0021 17.7 0.6 0.0021 17.7 0.4 3.7 2 1 1 3 3 2 2 IncA protein CENP-Q PF13094.1 KUM62513.1 - 0.0034 17.4 7.5 0.0034 17.4 5.2 4.7 2 2 2 4 4 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Baculo_PEP_C PF04513.7 KUM62513.1 - 0.0051 16.6 2.0 0.0051 16.6 1.4 4.0 3 1 1 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin PF00804.20 KUM62513.1 - 0.023 14.8 0.6 0.023 14.8 0.4 4.3 3 1 0 3 3 2 0 Syntaxin AT_hook PF02178.14 KUM62513.1 - 0.074 12.7 0.3 0.18 11.5 0.2 1.7 1 0 0 1 1 1 0 AT hook motif Filament PF00038.16 KUM62513.1 - 0.13 11.7 51.7 1.3 8.4 34.6 2.5 1 1 0 1 1 1 0 Intermediate filament protein Mitofilin PF09731.4 KUM62513.1 - 0.17 10.5 45.3 0.11 11.1 29.8 1.6 1 1 1 2 2 2 0 Mitochondrial inner membrane protein Reo_sigmaC PF04582.7 KUM62513.1 - 0.33 10.1 6.7 0.25 10.4 0.8 3.0 2 1 2 4 4 4 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 KUM62513.1 - 0.93 7.8 33.1 0.015 13.7 16.2 2.0 2 0 0 2 2 2 0 AAA domain FlaC_arch PF05377.6 KUM62513.1 - 1.4 8.8 12.8 7.7 6.5 3.0 4.9 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) RTBV_P46 PF06216.6 KUM62513.1 - 1.5 7.5 5.8 0.36 9.6 1.1 2.0 2 0 0 2 2 2 0 Rice tungro bacilliform virus P46 protein Lectin_N PF03954.9 KUM62513.1 - 1.6 8.1 7.7 0.86 9.0 0.5 3.3 3 1 0 3 3 3 0 Hepatic lectin, N-terminal domain DUF948 PF06103.6 KUM62513.1 - 3 7.7 20.3 0.1 12.4 1.5 5.5 4 2 2 6 6 6 0 Bacterial protein of unknown function (DUF948) Peptidase_S64 PF08192.6 KUM62513.1 - 4.5 5.4 13.5 13 3.9 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S64 DASH_Dam1 PF08653.5 KUM62513.1 - 5.5 6.8 6.6 7.2 6.4 1.6 3.0 2 1 1 3 3 3 0 DASH complex subunit Dam1 TMF_DNA_bd PF12329.3 KUM62513.1 - 6.5 6.6 50.9 0.081 12.7 5.0 6.9 2 2 3 6 6 6 0 TATA element modulatory factor 1 DNA binding Gly_transf_sug PF04488.10 KUM62514.1 - 6.1e-09 36.1 0.1 1.4e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 KUM62514.1 - 0.00074 18.7 0.1 0.001 18.2 0.1 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TraS PF10624.4 KUM62514.1 - 0.0022 17.5 0.0 0.0034 16.9 0.0 1.2 1 0 0 1 1 1 1 Plasmid conjugative transfer entry exclusion protein TraS MR_MLE_N PF02746.11 KUM62515.1 - 2.2e-14 53.4 0.0 5.3e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE_C PF13378.1 KUM62515.1 - 4.6e-14 52.3 0.0 7.8e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like Fe-ADH PF00465.14 KUM62516.1 - 1.3e-103 346.4 0.0 1.6e-103 346.1 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KUM62516.1 - 4.3e-15 55.7 0.0 8.3e-13 48.2 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 KUM62516.1 - 0.0014 18.1 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Toprim_3 PF13362.1 KUM62516.1 - 0.091 13.0 0.0 0.32 11.2 0.0 1.8 2 0 0 2 2 2 0 Toprim domain Arylsulfotran_2 PF14269.1 KUM62517.1 - 1e-112 376.1 8.4 1.3e-112 375.8 5.8 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) FAD_binding_7 PF03441.9 KUM62519.1 - 1.3e-50 172.2 0.4 1.5e-50 171.9 0.3 1.0 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase 2-Hacid_dh_C PF02826.14 KUM62521.1 - 4.9e-55 185.4 0.0 8.5e-55 184.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KUM62521.1 - 9.8e-36 122.1 0.1 1.7e-35 121.3 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.1 KUM62521.1 - 0.0061 16.8 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 XdhC Rossmann domain AlaDh_PNT_C PF01262.16 KUM62521.1 - 0.011 15.3 0.2 0.029 13.9 0.1 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.16 KUM62521.1 - 0.023 14.5 0.0 0.051 13.4 0.0 1.6 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 KUM62521.1 - 0.047 13.0 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain ACT PF01842.20 KUM62521.1 - 0.21 11.1 3.2 0.97 8.9 0.0 3.5 4 0 0 4 4 4 0 ACT domain Fungal_trans_2 PF11951.3 KUM62522.1 - 1.9e-07 30.0 0.2 3.6e-07 29.1 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM62522.1 - 2.7e-07 30.3 8.1 5.8e-07 29.3 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF336 PF03928.9 KUM62524.1 - 5.7e-17 61.7 1.5 2.6e-15 56.4 1.1 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF336) HSP70 PF00012.15 KUM62525.1 - 7.3e-263 872.9 15.2 8.3e-263 872.7 10.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KUM62525.1 - 5.1e-17 61.4 1.1 1.1e-15 57.0 0.2 2.2 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 KUM62525.1 - 0.002 17.0 0.9 0.013 14.3 0.1 2.4 2 1 1 3 3 3 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 KUM62525.1 - 0.051 12.6 5.2 0.22 10.6 0.1 3.4 4 0 0 4 4 4 0 Hydantoinase/oxoprolinase FtsA PF14450.1 KUM62525.1 - 1.5 8.6 5.1 4.5 7.1 0.1 3.5 3 1 0 3 3 3 0 Cell division protein FtsA GTP_EFTU PF00009.22 KUM62526.1 - 5.2e-51 172.7 0.0 8.2e-51 172.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 KUM62526.1 - 9.8e-15 54.4 3.6 1.9e-14 53.4 2.5 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D2 PF03144.20 KUM62526.1 - 5.8e-10 39.1 0.0 1.5e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KUM62526.1 - 7.1e-09 35.6 0.0 9.6e-08 31.9 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.12 KUM62526.1 - 2.4e-07 30.8 0.0 1.4e-06 28.4 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain Miro PF08477.8 KUM62526.1 - 0.0001 22.7 0.0 0.00063 20.2 0.0 2.4 1 1 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KUM62526.1 - 0.00028 20.1 0.1 0.037 13.2 0.0 2.8 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KUM62526.1 - 0.00054 19.1 0.1 0.0011 18.1 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 KUM62526.1 - 0.0032 16.7 0.0 1.4 8.1 0.0 2.3 1 1 1 2 2 2 2 ADP-ribosylation factor family Ras PF00071.17 KUM62526.1 - 0.011 15.1 0.1 0.26 10.6 0.0 2.2 2 0 0 2 2 2 0 Ras family Septin PF00735.13 KUM62526.1 - 0.018 14.0 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 Septin FeoB_N PF02421.13 KUM62526.1 - 0.025 13.8 0.5 0.63 9.3 0.1 2.8 2 1 0 2 2 2 0 Ferrous iron transport protein B Exotox-A_bind PF09101.5 KUM62527.1 - 0.059 12.4 0.0 0.068 12.2 0.0 1.1 1 0 0 1 1 1 0 Exotoxin A binding FAM176 PF14851.1 KUM62527.1 - 0.13 11.9 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 FAM176 family Cnd1_N PF12922.2 KUM62527.1 - 0.13 11.8 0.3 0.17 11.4 0.2 1.1 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term Vma12 PF11712.3 KUM62527.1 - 0.23 11.1 0.9 0.34 10.6 0.6 1.4 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2427 PF10348.4 KUM62527.1 - 0.95 9.0 3.9 1.2 8.6 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) zf-C2H2_2 PF12756.2 KUM62529.1 - 2.7e-37 126.9 20.0 8.2e-32 109.3 3.4 3.3 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KUM62529.1 - 4.3e-06 26.6 22.9 1.1e-05 25.3 5.1 3.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KUM62529.1 - 4.1e-05 23.6 6.3 4.1e-05 23.6 4.4 3.0 3 0 0 3 3 3 1 Zinc-finger of C2H2 type ASCH PF04266.9 KUM62529.1 - 0.036 14.4 0.1 0.08 13.3 0.0 1.5 1 0 0 1 1 1 0 ASCH domain DUF2777 PF10949.3 KUM62529.1 - 0.045 13.4 1.9 0.093 12.3 1.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2777) zf-C2H2 PF00096.21 KUM62529.1 - 0.053 13.8 23.2 0.086 13.2 1.8 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type AKAP95 PF04988.7 KUM62529.1 - 2.7 7.7 13.9 0.59 9.8 1.7 3.4 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_6 PF13912.1 KUM62529.1 - 4.7 7.2 14.7 1.7 8.6 0.1 3.4 3 1 0 3 3 3 0 C2H2-type zinc finger HECT PF00632.20 KUM62530.1 - 1.4e-75 254.3 0.0 2.4e-75 253.6 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Aminotran_1_2 PF00155.16 KUM62531.1 - 3.1e-53 181.0 0.0 3.6e-53 180.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HpcH_HpaI PF03328.9 KUM62532.1 - 1.7e-32 112.0 0.0 2.3e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.16 KUM62532.1 - 0.001 17.7 0.0 0.0016 17.1 0.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain TauD PF02668.11 KUM62533.1 - 6.3e-51 173.5 2.0 7.6e-51 173.2 1.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 KUM62533.1 - 0.00034 21.0 0.9 0.019 15.4 0.6 2.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily P16-Arc PF04699.9 KUM62533.1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Cys_Met_Meta_PP PF01053.15 KUM62534.1 - 3.2e-29 101.3 0.0 7.7e-29 100.1 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KUM62534.1 - 5.2e-07 28.9 0.0 8e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Peptidase_M20 PF01546.23 KUM62535.1 - 7.8e-24 84.2 0.0 3.5e-23 82.0 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 KUM62535.1 - 1.2e-09 37.6 15.6 0.0054 16.5 0.0 6.9 7 1 0 7 7 7 3 WD domain, G-beta repeat M20_dimer PF07687.9 KUM62535.1 - 8.8e-07 28.6 0.0 1.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KUM62535.1 - 0.0067 16.1 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 SOG2 PF10428.4 KUM62535.1 - 0.036 12.7 6.3 0.053 12.1 4.4 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein TraQ PF09679.5 KUM62536.1 - 0.053 13.4 0.2 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) PT PF04886.7 KUM62536.1 - 0.13 11.5 15.9 0.085 12.1 2.8 3.5 4 1 0 4 4 4 0 PT repeat DUF457 PF04307.9 KUM62537.1 - 0.31 10.3 2.9 0.34 10.2 1.4 1.4 1 1 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) Bys1 PF04681.7 KUM62538.1 - 5.2e-09 35.9 0.0 7.2e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein HpcH_HpaI PF03328.9 KUM62539.1 - 9e-27 93.3 0.0 2.1e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Sipho_Gp157 PF05565.6 KUM62539.1 - 0.063 12.8 10.4 0.13 11.8 2.5 2.3 2 0 0 2 2 2 0 Siphovirus Gp157 Prefoldin_2 PF01920.15 KUM62539.1 - 0.071 12.8 11.0 0.16 11.7 3.1 2.8 1 1 1 2 2 2 0 Prefoldin subunit Methyltransf_12 PF08242.7 KUM62539.1 - 0.09 13.2 0.8 1.5 9.3 0.0 3.0 2 1 1 3 3 3 0 Methyltransferase domain Ribosomal_L3 PF00297.17 KUM62539.1 - 0.44 9.9 1.7 13 5.0 1.8 2.1 2 0 0 2 2 2 0 Ribosomal protein L3 Nup88 PF10168.4 KUM62539.1 - 1.8 6.3 9.9 0.21 9.3 1.8 2.0 2 0 0 2 2 2 0 Nuclear pore component DUF1664 PF07889.7 KUM62539.1 - 5.2 6.8 8.0 2.9 7.7 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) HALZ PF02183.13 KUM62539.1 - 7.2 6.4 15.4 1.7 8.4 1.3 3.4 2 1 1 3 3 3 0 Homeobox associated leucine zipper TauD PF02668.11 KUM62540.1 - 7.5e-27 94.6 0.1 2.3e-26 93.0 0.0 1.7 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ribosomal_S6e PF01092.14 KUM62541.1 - 4.6e-59 197.6 0.7 7.8e-59 196.8 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S6e HMG_box PF00505.14 KUM62542.1 - 1.2e-23 83.1 0.8 2.2e-23 82.2 0.6 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KUM62542.1 - 2.2e-09 37.5 0.3 4.4e-09 36.5 0.2 1.5 1 0 0 1 1 1 1 HMG-box domain Ctf8 PF09696.5 KUM62543.1 - 7.9e-39 132.2 0.0 9.8e-39 131.9 0.0 1.1 1 0 0 1 1 1 1 Ctf8 Dabb PF07876.7 KUM62544.1 - 3.6e-12 46.5 0.0 4.3e-12 46.3 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Fungal_trans PF04082.13 KUM62546.1 - 1.7e-20 73.0 5.7 3e-20 72.2 3.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM62546.1 - 1.6e-06 27.8 14.1 3.3e-06 26.9 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0081 PF03652.10 KUM62546.1 - 0.23 11.5 0.2 0.5 10.4 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0081) MRG PF05712.8 KUM62547.1 - 5.8e-50 168.9 0.1 6.4e-50 168.7 0.0 1.0 1 0 0 1 1 1 1 MRG PPTA PF01239.17 KUM62548.1 - 1.1e-35 119.5 14.3 2.4e-08 32.9 0.0 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TIP49 PF06068.8 KUM62549.1 - 6.2e-187 621.1 0.0 7.1e-187 620.9 0.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 KUM62549.1 - 3.7e-11 42.5 0.6 7.9e-07 28.3 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 KUM62549.1 - 3.9e-11 43.2 0.1 3.9e-07 30.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KUM62549.1 - 5.1e-06 26.5 0.0 0.0081 16.1 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KUM62549.1 - 9.4e-06 25.7 0.2 0.15 12.1 0.0 2.4 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KUM62549.1 - 9e-05 22.1 0.1 0.00024 20.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 KUM62549.1 - 0.00031 20.7 0.1 0.00067 19.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KUM62549.1 - 0.00072 19.2 0.2 0.16 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 KUM62549.1 - 0.0013 17.8 0.2 0.0029 16.7 0.2 1.5 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 KUM62549.1 - 0.0014 18.1 0.1 1.2 8.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.1 KUM62549.1 - 0.0026 17.2 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KUM62549.1 - 0.014 14.5 0.1 0.65 9.1 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KUM62549.1 - 0.025 14.0 0.1 0.049 13.0 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.4 KUM62549.1 - 0.029 13.3 0.0 0.053 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 KUM62549.1 - 0.039 13.0 0.4 0.12 11.4 0.1 1.9 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.1 KUM62549.1 - 0.042 14.1 0.1 0.22 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KUM62549.1 - 0.066 14.0 0.1 0.21 12.4 0.0 1.9 2 1 0 2 2 1 0 AAA domain DnaB_C PF03796.10 KUM62549.1 - 0.092 11.6 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain CN_hydrolase PF00795.17 KUM62550.1 - 1e-21 77.1 0.0 1.4e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase An_peroxidase PF03098.10 KUM62551.1 - 7.9e-97 324.8 0.0 2.7e-94 316.4 0.0 2.1 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 KUM62551.1 - 6.5e-09 34.8 0.1 2.4e-07 29.6 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 DUF2359 PF10151.4 KUM62551.1 - 0.015 13.8 0.1 0.023 13.2 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2359) DUF2407_C PF13373.1 KUM62553.1 - 1.3e-43 148.2 0.4 2e-43 147.6 0.3 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 KUM62553.1 - 1.8e-31 108.1 0.0 4.4e-31 106.9 0.0 1.6 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 KUM62553.1 - 0.00022 20.5 0.0 0.00042 19.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF515 PF04415.7 KUM62553.1 - 0.32 9.1 3.7 0.45 8.6 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) V-SNARE PF05008.10 KUM62554.1 - 4.7e-20 71.5 4.4 4.7e-20 71.5 3.1 2.3 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 KUM62554.1 - 1.6e-15 56.9 4.5 1.6e-15 56.9 3.1 2.8 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KUM62554.1 - 0.00044 19.8 0.3 0.00044 19.8 0.2 2.3 2 1 0 2 2 2 1 Sec20 Fusion_gly PF00523.13 KUM62554.1 - 0.0026 15.9 2.4 0.0036 15.4 0.2 2.0 2 0 0 2 2 2 1 Fusion glycoprotein F0 DUF1978 PF09321.5 KUM62554.1 - 0.0054 16.2 8.2 0.008 15.6 5.6 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1978) TMP_2 PF06791.8 KUM62554.1 - 0.018 14.6 3.3 1.9 8.0 0.1 2.1 2 0 0 2 2 2 0 Prophage tail length tape measure protein DUF825 PF05695.7 KUM62554.1 - 0.019 12.4 0.2 0.017 12.5 0.2 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) Spc7 PF08317.6 KUM62554.1 - 0.036 12.7 11.1 0.0095 14.6 3.9 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Sec8_exocyst PF04048.9 KUM62554.1 - 0.7 9.5 6.4 4.6 6.8 0.0 2.9 3 1 0 3 3 3 0 Sec8 exocyst complex component specific domain ZapA PF05164.8 KUM62554.1 - 0.77 9.7 12.7 0.48 10.4 0.1 3.5 2 1 0 2 2 2 0 Cell division protein ZapA Synaptobrevin PF00957.16 KUM62554.1 - 0.97 9.0 8.3 0.19 11.3 1.7 2.7 3 2 1 4 4 4 0 Synaptobrevin Mnd1 PF03962.10 KUM62554.1 - 2.4 7.7 12.4 0.77 9.3 2.8 2.4 1 1 1 2 2 2 0 Mnd1 family zf-C4H2 PF10146.4 KUM62554.1 - 3.2 7.7 7.0 0.92 9.4 0.6 2.1 1 1 1 2 2 2 0 Zinc finger-containing protein Steroid_dh PF02544.11 KUM62555.1 - 2.8e-31 108.3 1.2 3.7e-31 107.9 0.9 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KUM62555.1 - 9.5e-07 28.3 1.7 1.4e-06 27.7 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 KUM62555.1 - 0.00013 21.9 0.6 0.00029 20.8 0.4 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase Cnl2_NKP2 PF09447.5 KUM62556.1 - 8.6e-29 99.0 1.8 3e-28 97.2 0.5 2.2 2 0 0 2 2 2 1 Cnl2/NKP2 family protein Reo_sigmaC PF04582.7 KUM62556.1 - 0.015 14.4 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein EAP30 PF04157.11 KUM62556.1 - 0.017 14.2 0.3 0.027 13.6 0.1 1.5 1 1 0 1 1 1 0 EAP30/Vps36 family KfrA_N PF11740.3 KUM62556.1 - 0.023 15.1 2.1 0.81 10.1 0.2 2.2 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Rabaptin PF03528.10 KUM62556.1 - 0.066 13.1 2.4 0.53 10.2 0.0 2.3 2 0 0 2 2 2 0 Rabaptin 5_3_exonuc PF01367.15 KUM62556.1 - 0.072 13.3 0.4 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold CENP-H PF05837.7 KUM62556.1 - 0.099 12.8 2.2 2.1 8.5 0.7 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) GlutR_dimer PF00745.15 KUM62556.1 - 0.14 12.0 2.5 0.11 12.4 0.5 1.7 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Osmo_CC PF08946.5 KUM62556.1 - 0.33 11.0 4.6 2.8 8.0 0.0 2.8 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Glyco_transf_34 PF05637.7 KUM62558.1 - 5.8e-63 212.5 0.0 7.9e-63 212.1 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 KUM62558.1 - 0.015 14.6 0.0 0.065 12.5 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function, DUF273 Aa_trans PF01490.13 KUM62560.1 - 2.2e-48 164.7 32.4 2.5e-48 164.5 22.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Utp12 PF04003.7 KUM62562.1 - 1.3e-22 79.7 0.0 2e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family HAUS4 PF14735.1 KUM62563.1 - 3.8e-06 26.3 1.1 3.8e-06 26.3 0.8 2.0 2 1 0 2 2 2 1 HAUS augmin-like complex subunit 4 DinB_2 PF12867.2 KUM62563.1 - 0.81 10.0 7.1 2.1 8.6 0.2 3.0 2 1 1 3 3 3 0 DinB superfamily RBD-FIP PF09457.5 KUM62563.1 - 9.9 6.0 9.3 7.3 6.4 0.2 3.2 3 0 0 3 3 3 0 FIP domain Bromodomain PF00439.20 KUM62564.1 - 9.8e-39 131.1 0.9 1.1e-21 76.4 0.1 2.6 2 0 0 2 2 2 2 Bromodomain DUF3573 PF12097.3 KUM62564.1 - 1.3 7.5 5.3 1.2 7.6 2.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) Frataxin_Cyay PF01491.11 KUM62565.1 - 3.1e-33 113.8 0.0 4.3e-33 113.3 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain zf-CSL PF05207.8 KUM62566.1 - 9.8e-25 85.8 0.8 1.3e-24 85.4 0.6 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 KUM62566.1 - 0.015 15.2 0.2 0.028 14.3 0.2 1.4 1 0 0 1 1 1 0 Zinc ribbon domain DUF3987 PF13148.1 KUM62567.1 - 0.0052 15.3 0.2 0.0052 15.3 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) Glyco_hydro_cc PF11790.3 KUM62568.1 - 1.5e-66 224.2 0.6 1.7e-66 224.0 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core WD40 PF00400.27 KUM62569.1 - 3.2e-13 48.9 0.4 3.6e-07 29.8 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Corona_nucleoca PF00937.13 KUM62569.1 - 0.11 11.4 3.2 0.18 10.7 2.2 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Pribosyltran_N PF13793.1 KUM62571.1 - 2.5e-45 152.9 1.0 2.3e-44 149.8 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KUM62571.1 - 2.3e-39 135.0 1.6 1.3e-32 113.0 0.5 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KUM62571.1 - 3e-13 49.5 0.7 2.6e-12 46.5 0.4 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KUM62571.1 - 7.4e-05 22.0 0.2 0.00014 21.1 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Chlorosome_CsmC PF11098.3 KUM62571.1 - 0.026 14.2 1.1 0.048 13.3 0.7 1.4 1 0 0 1 1 1 0 Chlorosome envelope protein C DUF913 PF06025.7 KUM62572.1 - 7.5e-150 498.8 0.0 7.5e-150 498.8 0.0 3.5 4 0 0 4 4 4 1 Domain of Unknown Function (DUF913) HECT PF00632.20 KUM62572.1 - 8.1e-96 320.8 0.0 1.4e-95 320.1 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 KUM62572.1 - 2.9e-88 296.3 4.1 9.7e-88 294.6 2.2 2.5 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 KUM62572.1 - 1.1e-31 108.9 7.7 1.1e-31 108.9 5.3 4.2 3 1 0 3 3 3 1 Domain of unknown function (DUF4414) Tudor-knot PF11717.3 KUM62573.1 - 6e-09 35.4 3.1 1.2e-08 34.5 2.1 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 KUM62573.1 - 0.00085 18.9 1.9 0.0016 18.0 1.3 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Glyoxalase PF00903.20 KUM62574.1 - 2.9e-17 62.8 0.1 3.6e-14 52.8 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KUM62574.1 - 1.3e-12 47.7 0.1 1e-05 25.5 0.0 3.1 2 2 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KUM62574.1 - 4.7e-07 30.3 0.1 0.005 17.4 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 KUM62574.1 - 2.9e-06 27.2 0.0 0.16 11.8 0.0 3.2 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 KUM62574.1 - 7.8e-05 22.6 0.1 0.093 12.6 0.0 3.1 3 0 0 3 3 3 2 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal RabGAP-TBC PF00566.13 KUM62575.1 - 4.9e-51 173.2 0.4 3.6e-50 170.4 0.0 2.6 2 1 0 2 2 2 1 Rab-GTPase-TBC domain Fe-S_biosyn PF01521.15 KUM62576.1 - 1.4e-18 66.8 0.0 1.9e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF566 PF04484.7 KUM62576.1 - 3.3 7.1 8.5 4.2 6.8 5.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF1741 PF08427.5 KUM62577.1 - 3.1e-90 301.7 0.0 1.3e-89 299.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) MBOAT_2 PF13813.1 KUM62577.1 - 0.024 14.6 0.1 0.081 13.0 0.1 1.9 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family PTR2 PF00854.16 KUM62578.1 - 1.5e-38 132.5 18.9 1.1e-37 129.7 13.1 2.3 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 KUM62578.1 - 1.2e-10 40.6 23.0 1.2e-09 37.3 15.5 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF1469 PF07332.6 KUM62578.1 - 4.2 7.1 7.9 0.72 9.6 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) Abhydrolase_1 PF00561.15 KUM62581.1 - 4.1e-43 147.5 0.0 2.1e-42 145.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KUM62581.1 - 5.2e-14 52.6 0.8 2.4e-13 50.5 0.5 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM62581.1 - 0.00072 19.3 0.1 0.058 13.1 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KUM62581.1 - 0.045 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein PLA2_B PF01735.13 KUM62582.1 - 6.2e-207 687.6 1.8 7.4e-207 687.3 1.2 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PTCB-BRCT PF12738.2 KUM62583.1 - 0.19 11.6 0.1 0.77 9.6 0.1 2.0 1 1 0 1 1 1 0 twin BRCT domain DAHP_synth_2 PF01474.11 KUM62584.1 - 3e-194 645.4 0.0 3.4e-194 645.2 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family FMN_bind_2 PF04299.7 KUM62586.1 - 4e-54 182.6 0.0 4.8e-54 182.3 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Sulfatase PF00884.18 KUM62587.1 - 2.7e-19 69.5 1.7 4.7e-19 68.6 1.2 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KUM62587.1 - 2.9e-07 30.1 0.1 6.2e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KUM62587.1 - 0.00071 18.1 0.1 0.0012 17.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) adh_short_C2 PF13561.1 KUM62588.1 - 1.7e-29 103.2 0.0 2e-29 103.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KUM62588.1 - 2e-28 99.3 2.5 2.6e-28 99.0 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM62588.1 - 5.7e-16 58.6 1.2 7.8e-16 58.2 0.8 1.1 1 0 0 1 1 1 1 KR domain Vir_act_alpha_C PF10400.4 KUM62588.1 - 0.044 14.1 0.2 0.073 13.4 0.1 1.3 1 0 0 1 1 1 0 Virulence activator alpha C-term Fungal_trans PF04082.13 KUM62589.1 - 1.4e-13 50.3 1.9 1.4e-13 50.3 1.3 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain COG2 PF06148.6 KUM62590.1 - 0.058 13.2 1.0 0.087 12.6 0.7 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF16 PF01519.11 KUM62590.1 - 0.07 13.3 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 Remorin_C PF03763.8 KUM62590.1 - 0.098 12.1 5.6 0.08 12.4 3.0 1.4 1 1 0 1 1 1 0 Remorin, C-terminal region bZIP_2 PF07716.10 KUM62590.1 - 0.19 11.5 11.3 0.32 10.8 7.8 1.4 1 0 0 1 1 1 0 Basic region leucine zipper adh_short PF00106.20 KUM62591.1 - 9.8e-20 71.1 0.1 3.3e-19 69.4 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM62591.1 - 5.7e-10 39.1 0.0 7.8e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KUM62591.1 - 1.2e-06 28.5 0.0 1.7e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Saccharop_dh PF03435.13 KUM62591.1 - 7e-05 21.9 0.0 0.00013 21.1 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 KUM62591.1 - 0.0052 16.0 0.0 0.0076 15.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KUM62591.1 - 0.0058 16.6 0.1 0.0098 15.9 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KUM62591.1 - 0.019 13.9 0.0 0.045 12.6 0.0 1.6 1 1 0 1 1 1 0 Male sterility protein Aldedh PF00171.17 KUM62592.1 - 4.3e-186 618.7 0.2 4.9e-186 618.5 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KUM62592.1 - 0.0015 17.7 0.0 0.0029 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) IPI_T4 PF11634.3 KUM62592.1 - 0.022 14.6 0.1 2.8 7.8 0.0 2.8 3 0 0 3 3 3 0 Nuclease inhibitor from bacteriophage T4 SGL PF08450.7 KUM62593.1 - 5.8e-72 242.0 0.0 7.3e-72 241.6 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region JAB PF01398.16 KUM62595.1 - 8.1e-08 32.0 0.0 3.7e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF4557 PF15101.1 KUM62595.1 - 0.085 12.6 0.7 0.14 11.9 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) MitMem_reg PF13012.1 KUM62595.1 - 0.1 12.7 2.4 0.51 10.4 1.7 2.2 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function FAD_binding_1 PF00667.15 KUM62596.1 - 2.7e-31 108.7 0.0 4.2e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KUM62596.1 - 3.2e-29 101.7 0.0 5.6e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KUM62596.1 - 2e-15 57.2 0.0 1.5e-14 54.4 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KUM62596.1 - 0.00094 19.1 0.0 0.0037 17.2 0.0 1.9 1 1 1 2 2 2 1 Flavodoxin domain Flavodoxin_3 PF12641.2 KUM62596.1 - 0.0013 18.1 0.0 0.0042 16.5 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin domain RNA_pol_3_Rpc31 PF11705.3 KUM62597.1 - 1.6e-56 191.8 11.9 2e-56 191.5 8.2 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Cut8_N PF14482.1 KUM62597.1 - 0.12 12.4 1.8 1.1 9.3 0.0 2.7 3 0 0 3 3 3 0 Cut8 proteasome-binding domain Glyco_hydro_67M PF07488.7 KUM62598.1 - 9.5e-151 501.2 0.2 1.3e-150 500.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.7 KUM62598.1 - 2.3e-96 321.5 5.2 3.5e-96 320.9 3.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.9 KUM62598.1 - 5.1e-33 113.6 0.0 9.5e-33 112.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus BetaGal_dom4_5 PF13364.1 KUM62598.1 - 0.00067 19.8 0.9 0.0076 16.5 0.3 2.4 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Glyco_hydro_20b PF02838.10 KUM62598.1 - 0.0036 17.8 0.0 0.0097 16.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Ribosomal_L7Ae PF01248.21 KUM62599.1 - 3.2e-26 90.6 0.0 3.6e-26 90.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Solute_trans_a PF03619.11 KUM62600.1 - 5.7e-86 288.2 20.0 6.8e-86 287.9 13.9 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF1129 PF06570.6 KUM62600.1 - 6.4 6.0 10.9 0.9 8.8 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) SAP PF02037.22 KUM62601.1 - 7.9e-09 34.8 0.2 1.4e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 SAP domain AhpC-TSA PF00578.16 KUM62602.1 - 6.3e-33 113.1 0.0 1.1e-32 112.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KUM62602.1 - 2.3e-14 53.1 0.0 3.1e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 KUM62602.1 - 3.6e-14 52.1 0.1 5.8e-14 51.4 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Peptidase_S8 PF00082.17 KUM62603.1 - 1.2e-12 47.6 0.0 1.9e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Subtilase family PGBA_C PF15437.1 KUM62603.1 - 0.018 15.1 1.3 0.018 15.1 0.9 1.9 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal EVE PF01878.13 KUM62604.1 - 7.1e-51 171.9 0.5 1.2e-50 171.3 0.3 1.3 1 0 0 1 1 1 1 EVE domain AT_hook PF02178.14 KUM62604.1 - 5.5e-06 25.4 45.9 0.029 14.0 1.4 5.1 5 0 0 5 5 5 4 AT hook motif Kelch_4 PF13418.1 KUM62606.1 - 1.7e-20 72.4 0.0 2.3e-08 33.6 0.0 5.2 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 KUM62606.1 - 1.8e-18 66.1 2.5 1e-10 41.4 0.0 5.0 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.1 KUM62606.1 - 4.4e-11 42.4 6.6 0.00015 21.6 0.0 4.2 4 1 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 KUM62606.1 - 3.3e-10 39.2 0.1 0.00084 19.0 0.0 4.7 4 1 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 KUM62606.1 - 4e-09 35.8 0.0 0.037 13.5 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 KUM62606.1 - 2.2e-08 33.8 3.8 0.016 15.3 0.0 5.0 3 1 1 4 4 4 2 Kelch motif BTB PF00651.26 KUM62606.1 - 0.1 12.5 0.0 0.59 10.1 0.0 2.0 2 0 0 2 2 2 0 BTB/POZ domain PNP_UDP_1 PF01048.15 KUM62607.1 - 0.00011 21.2 0.0 0.00053 19.0 0.0 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily zf-C2H2_4 PF13894.1 KUM62607.1 - 0.85 10.1 12.6 6 7.4 0.2 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger Pkinase PF00069.20 KUM62608.1 - 1.4e-10 40.8 0.0 4.2e-09 35.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KUM62608.1 - 0.00054 19.0 0.2 0.0014 17.7 0.1 1.6 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KUM62608.1 - 0.0015 17.6 0.0 0.039 13.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Ribophorin_II PF05817.9 KUM62609.1 - 7.4e-23 80.6 0.0 9.1e-23 80.3 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II WD40 PF00400.27 KUM62611.1 - 9.7e-15 53.8 8.9 3.4e-06 26.7 0.0 6.0 6 1 0 6 6 6 4 WD domain, G-beta repeat ATP-synt_E PF05680.7 KUM62612.1 - 2.6e-26 91.4 1.1 2.8e-26 91.2 0.7 1.0 1 0 0 1 1 1 1 ATP synthase E chain FCH PF00611.18 KUM62612.1 - 0.029 14.5 1.2 0.036 14.2 0.8 1.3 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Chordopox_A13L PF05961.6 KUM62612.1 - 0.43 10.5 2.5 0.72 9.8 0.5 1.9 1 1 1 2 2 2 0 Chordopoxvirus A13L protein PCI_Csn8 PF10075.4 KUM62613.1 - 2.9e-31 108.1 0.0 4.3e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 KUM62613.1 - 1.1e-05 25.1 0.0 1.3e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family SDH_sah PF01972.11 KUM62613.1 - 0.12 11.1 0.0 0.5 9.0 0.0 1.8 2 0 0 2 2 2 0 Serine dehydrogenase proteinase PCI PF01399.22 KUM62613.1 - 0.13 12.5 0.2 0.33 11.3 0.0 1.7 2 1 0 2 2 2 0 PCI domain zf-C3Hc3H PF13891.1 KUM62614.1 - 0.1 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Potential DNA-binding domain DUF1275 PF06912.6 KUM62615.1 - 1.2e-29 103.0 7.4 1.5e-29 102.6 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF4131 PF13567.1 KUM62615.1 - 0.66 9.3 4.5 8.1 5.8 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Con-6 PF10346.4 KUM62616.1 - 1.8e-26 91.2 5.3 1.3e-15 56.4 0.7 2.1 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.2 KUM62616.1 - 0.03 13.8 0.1 0.09 12.2 0.0 1.7 2 0 0 2 2 2 0 SpoIIIAH-like protein ATP-synt_DE PF00401.15 KUM62616.1 - 4.9 7.1 9.8 0.49 10.3 1.1 3.0 3 1 0 3 3 3 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain FMO-like PF00743.14 KUM62617.1 - 6.8e-27 93.8 0.0 4.3e-09 35.1 0.0 3.1 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KUM62617.1 - 3.5e-19 69.6 0.0 2.3e-17 63.7 0.0 2.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM62617.1 - 1.2e-09 38.1 0.2 1.8e-07 31.0 0.2 3.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KUM62617.1 - 1.7e-07 31.3 0.0 0.016 15.0 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KUM62617.1 - 9.3e-07 28.0 0.3 0.0042 16.0 0.0 3.4 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KUM62617.1 - 5e-06 26.4 0.0 1.9e-05 24.6 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KUM62617.1 - 0.0033 16.5 0.2 0.045 12.8 0.0 2.3 3 0 0 3 3 3 1 Thi4 family DAO PF01266.19 KUM62617.1 - 0.0055 15.6 0.0 5.5 5.7 0.0 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KUM62617.1 - 0.033 13.2 0.0 0.062 12.3 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase PdxA PF04166.7 KUM62617.1 - 0.05 12.7 0.0 0.078 12.1 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA Shikimate_DH PF01488.15 KUM62617.1 - 0.054 13.6 0.0 5.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KUM62617.1 - 0.066 13.6 0.9 9.5 6.7 0.0 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase OCD_Mu_crystall PF02423.10 KUM62617.1 - 0.1 11.3 0.0 0.39 9.4 0.0 1.8 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family HI0933_like PF03486.9 KUM62617.1 - 0.2 10.0 0.1 0.57 8.6 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein DUF3453 PF11935.3 KUM62618.1 - 5.2e-72 242.1 0.0 9.5e-72 241.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) Sds3 PF08598.6 KUM62619.1 - 1.3e-28 99.9 3.8 1.3e-28 99.9 2.6 3.1 3 1 0 3 3 3 1 Sds3-like Ku_PK_bind PF08785.6 KUM62619.1 - 0.045 13.6 0.1 0.083 12.7 0.1 1.4 1 0 0 1 1 1 0 Ku C terminal domain like STT3 PF02516.9 KUM62620.1 - 1.2e-17 64.0 0.1 1.4e-17 63.8 0.1 1.0 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Pyr_redox_3 PF13738.1 KUM62621.1 - 2.2e-19 70.3 0.2 3.7e-19 69.5 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KUM62621.1 - 5.3e-11 41.4 0.0 1e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KUM62621.1 - 4.3e-08 33.2 0.0 4.6e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KUM62621.1 - 1.1e-07 31.0 0.0 2e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KUM62621.1 - 2.1e-07 30.8 0.1 6.4e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KUM62621.1 - 0.0002 20.4 0.2 0.035 13.0 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.12 KUM62621.1 - 0.00043 19.4 0.2 0.002 17.2 0.1 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 KUM62621.1 - 0.00063 19.5 0.3 0.0062 16.3 0.2 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KUM62621.1 - 0.0031 16.4 0.0 0.0065 15.4 0.0 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 KUM62621.1 - 0.0073 14.8 0.3 0.39 9.1 0.1 2.3 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KUM62621.1 - 0.1 11.4 0.1 0.19 10.5 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 KUM62621.1 - 0.16 12.4 0.2 2.7 8.4 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase STT3 PF02516.9 KUM62622.1 - 2.9e-101 339.8 34.1 1.8e-96 324.0 22.4 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit NAD_binding_1 PF00175.16 KUM62623.1 - 1.4e-30 106.0 0.0 2.4e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KUM62623.1 - 3.6e-26 91.1 0.0 9.4e-26 89.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 KUM62623.1 - 2e-23 81.9 0.2 4.8e-23 80.7 0.2 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 KUM62623.1 - 8.4e-06 25.7 0.0 0.00023 21.1 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain PSI_PSAK PF01241.13 KUM62623.1 - 0.056 13.4 1.1 0.13 12.2 0.8 1.6 1 0 0 1 1 1 0 Photosystem I psaG / psaK FAD_binding_9 PF08021.6 KUM62623.1 - 0.059 13.3 0.0 0.68 9.9 0.0 2.3 1 1 0 1 1 1 0 Siderophore-interacting FAD-binding domain p450 PF00067.17 KUM62624.1 - 2.2e-69 234.2 0.0 2.6e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 KUM62626.1 - 3.3e-28 98.2 0.6 5e-28 97.6 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain 3HCDH_N PF02737.13 KUM62627.1 - 4.8e-32 111.0 0.0 6.6e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KUM62627.1 - 1.6e-08 34.8 0.0 3.1e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 KUM62627.1 - 9.6e-07 28.6 0.0 1.5e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 KUM62627.1 - 0.00079 19.3 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.9 KUM62627.1 - 0.057 12.7 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ldl_recept_b PF00058.12 KUM62627.1 - 0.077 13.3 2.3 14 6.0 0.1 4.2 3 1 0 3 3 3 0 Low-density lipoprotein receptor repeat class B 2-Hacid_dh_C PF02826.14 KUM62627.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Notch PF00066.12 KUM62627.1 - 0.21 11.8 2.2 0.5 10.6 1.5 1.6 1 0 0 1 1 1 0 LNR domain DUF3466 PF11949.3 KUM62628.1 - 0.016 13.8 0.0 0.38 9.2 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3466) ADH_N PF08240.7 KUM62629.1 - 2.1e-20 72.5 1.2 4e-20 71.6 0.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM62629.1 - 3.6e-17 62.1 0.0 6.1e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KUM62629.1 - 8.7e-05 21.7 0.3 0.00015 20.9 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KUM62629.1 - 0.00016 21.2 1.0 0.00031 20.3 0.7 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 KUM62629.1 - 0.014 15.2 0.1 0.023 14.5 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 KUM62629.1 - 0.019 14.6 0.1 0.03 13.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 KUM62629.1 - 0.028 14.2 0.2 0.043 13.6 0.2 1.3 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.15 KUM62629.1 - 0.042 13.9 0.0 0.063 13.3 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MAF_flag10 PF01973.13 KUM62629.1 - 0.046 13.2 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF115 XdhC_C PF13478.1 KUM62629.1 - 0.13 12.5 0.0 0.31 11.3 0.0 1.6 2 0 0 2 2 2 0 XdhC Rossmann domain Ank_2 PF12796.2 KUM62630.1 - 5.8e-77 254.1 0.1 1e-12 48.2 0.0 4.5 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KUM62630.1 - 4.7e-42 139.7 1.7 7e-06 25.5 0.0 8.1 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.1 KUM62630.1 - 1.8e-39 133.4 8.6 1.4e-09 38.1 0.0 6.5 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM62630.1 - 1.1e-34 117.6 10.1 2.3e-08 33.9 0.2 5.4 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM62630.1 - 3.2e-30 101.1 0.0 0.0028 17.7 0.0 8.2 8 0 0 8 8 8 6 Ankyrin repeat DUF3734 PF12536.3 KUM62630.1 - 0.028 14.5 0.3 15 5.7 0.0 3.6 3 1 1 4 4 4 0 Patatin phospholipase Phenol_monoox PF04663.7 KUM62630.1 - 0.089 12.5 0.0 19 5.0 0.0 2.5 2 0 0 2 2 2 0 Phenol hydroxylase conserved region DUF3017 PF11222.3 KUM62630.1 - 0.47 10.2 3.2 22 4.9 0.0 4.5 6 0 0 6 6 6 0 Protein of unknown function (DUF3017) His_Phos_1 PF00300.17 KUM62631.1 - 0.053 13.5 0.0 0.058 13.4 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) AP_endonuc_2 PF01261.19 KUM62632.1 - 2.4e-11 43.3 0.0 3.5e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel F-box-like PF12937.2 KUM62633.1 - 0.00065 19.3 0.0 0.0014 18.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like IucA_IucC PF04183.7 KUM62633.1 - 0.013 14.7 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 IucA / IucC family Redoxin PF08534.5 KUM62634.1 - 1.2e-37 128.6 0.0 1.3e-37 128.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KUM62634.1 - 7.5e-15 54.7 0.0 9.9e-15 54.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family MFS_1 PF07690.11 KUM62635.1 - 3.4e-23 81.9 17.5 3.7e-23 81.8 12.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF912 PF06024.7 KUM62636.1 - 0.00038 20.4 0.1 0.00049 20.1 0.1 1.3 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) MFS_1 PF07690.11 KUM62636.1 - 0.0017 17.1 0.0 0.002 16.9 0.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily BT1 PF03092.11 KUM62636.1 - 0.0022 16.7 0.0 0.0029 16.3 0.0 1.1 1 0 0 1 1 1 1 BT1 family AmoA PF05145.7 KUM62636.1 - 0.0063 15.5 0.5 0.0081 15.2 0.4 1.1 1 0 0 1 1 1 1 Putative ammonia monooxygenase DUF4079 PF13301.1 KUM62636.1 - 0.0073 16.3 0.3 0.011 15.7 0.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF4079) CCSMST1 PF15013.1 KUM62636.1 - 0.0081 16.0 0.1 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 CCSMST1 family DUF1275 PF06912.6 KUM62636.1 - 0.019 14.1 0.5 0.024 13.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) DUF2407_C PF13373.1 KUM62636.1 - 0.15 11.9 0.2 3.2 7.6 0.2 2.0 2 0 0 2 2 2 0 DUF2407 C-terminal domain Phage_holin_4 PF05105.7 KUM62636.1 - 0.18 11.4 1.3 0.29 10.8 0.9 1.4 1 1 0 1 1 1 0 Holin family Pyr_redox_3 PF13738.1 KUM62637.1 - 7.8e-28 97.9 0.0 1.5e-27 97.0 0.0 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM62637.1 - 1.9e-06 27.7 0.0 6.4e-05 22.7 0.0 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KUM62637.1 - 5.7e-06 26.3 0.0 2.2e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KUM62637.1 - 0.00023 20.1 0.0 0.0044 15.9 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) RRM_1 PF00076.17 KUM62638.1 - 0.00015 21.2 0.0 0.032 13.8 0.0 3.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM62638.1 - 0.0015 18.3 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 KUM62638.1 - 0.0016 17.0 24.3 0.0016 17.0 16.8 2.4 2 1 0 2 2 2 1 Microtubule-binding protein MIP-T3 RRM_6 PF14259.1 KUM62638.1 - 0.065 13.2 0.0 0.3 11.1 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Asp-B-Hydro_N PF05279.6 KUM62638.1 - 0.91 9.3 31.2 7.4 6.3 18.8 2.5 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region BTV_NS2 PF04514.7 KUM62638.1 - 4.4 6.0 24.7 0.48 9.2 12.7 2.2 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 UL40 PF10682.4 KUM62640.1 - 0.1 12.0 2.4 1.3 8.4 0.1 2.2 1 1 1 2 2 2 0 Glycoprotein of human cytomegalovirus HHV-5 PQ-loop PF04193.9 KUM62640.1 - 0.21 11.1 2.3 0.27 10.8 0.3 2.1 2 0 0 2 2 2 0 PQ loop repeat Acetyltransf_3 PF13302.1 KUM62641.1 - 1.3e-19 70.7 0.0 1.9e-19 70.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KUM62641.1 - 6.1e-10 38.9 0.0 1.2e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KUM62641.1 - 0.00011 22.1 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KUM62641.1 - 0.00047 19.8 0.0 0.0014 18.3 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.1 KUM62641.1 - 0.0045 16.9 0.0 0.0098 15.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FA_desaturase PF00487.19 KUM62642.1 - 7.7e-32 110.7 21.5 1.2e-31 110.1 14.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KUM62642.1 - 0.15 12.0 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) DUF1275 PF06912.6 KUM62643.1 - 3.3e-05 23.1 0.4 4.6e-05 22.7 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF4603 PF15376.1 KUM62643.1 - 0.016 12.4 0.0 0.02 12.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) CrtC PF07143.6 KUM62645.1 - 1.2e-15 57.6 0.1 1.9e-15 56.9 0.1 1.3 1 0 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) zf-C2H2 PF00096.21 KUM62646.1 - 5.5e-11 42.1 13.1 1.1e-05 25.4 1.3 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KUM62646.1 - 2.3e-09 36.9 8.0 4.8e-05 23.4 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KUM62646.1 - 5e-09 35.9 9.7 7.9e-07 29.0 1.5 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.1 KUM62646.1 - 0.00025 21.1 7.9 0.019 15.1 1.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 KUM62646.1 - 0.00046 20.2 3.0 0.013 15.5 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KUM62646.1 - 0.012 15.5 4.3 0.42 10.5 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-CHY PF05495.7 KUM62646.1 - 0.068 13.3 0.6 0.12 12.5 0.4 1.3 1 0 0 1 1 1 0 CHY zinc finger zf-met PF12874.2 KUM62646.1 - 0.21 11.8 0.2 0.21 11.8 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.10 KUM62646.1 - 0.38 10.5 4.0 0.22 11.3 0.2 2.2 2 0 0 2 2 2 0 BED zinc finger GPI-anchored PF10342.4 KUM62648.1 - 7.3e-13 48.8 4.0 7.3e-13 48.8 2.7 4.2 2 2 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 KUM62648.1 - 0.00011 21.6 0.9 0.00021 20.8 0.2 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF4448) DUF605 PF04652.11 KUM62648.1 - 0.26 10.6 16.9 0.32 10.3 11.7 1.1 1 0 0 1 1 1 0 Vta1 like DUF572 PF04502.8 KUM62648.1 - 4.6 6.3 16.0 6.2 5.9 11.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3827 PF12877.2 KUM62648.1 - 10 4.1 14.4 11 3.9 10.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) NUFIP1 PF10453.4 KUM62649.1 - 1.4e-17 62.8 2.0 1.4e-17 62.8 1.4 3.7 4 1 1 5 5 5 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 KUM62649.1 - 4.7e-09 35.7 4.0 8.5e-09 34.8 2.8 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Sugar_tr PF00083.19 KUM62651.1 - 1.1e-104 350.5 17.8 1.3e-104 350.3 12.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM62651.1 - 7.3e-22 77.5 27.9 4.3e-21 75.0 14.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM151 PF14857.1 KUM62651.1 - 0.065 11.8 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 TMEM151 family Atrophin-1 PF03154.10 KUM62652.1 - 0.61 8.1 7.1 0.64 8.0 4.9 1.0 1 0 0 1 1 1 0 Atrophin-1 family PolyA_pol PF01743.15 KUM62653.1 - 0.079 13.1 2.1 0.088 13.0 0.1 2.0 2 0 0 2 2 2 0 Poly A polymerase head domain Hydrolase_like PF13242.1 KUM62654.1 - 2.7e-07 30.1 0.1 3.9e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 KUM62654.1 - 0.00012 22.3 0.0 0.00015 22.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KUM62654.1 - 0.00044 20.7 0.0 0.00052 20.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ORMDL PF04061.9 KUM62655.1 - 3.5e-60 201.4 3.6 4.4e-60 201.1 2.5 1.1 1 0 0 1 1 1 1 ORMDL family CH PF00307.26 KUM62657.1 - 6.7e-13 48.6 0.0 1.1e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain TPR_12 PF13424.1 KUM62659.1 - 1.1e-07 31.7 12.2 0.00015 21.6 0.4 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 KUM62659.1 - 0.012 15.1 0.3 0.012 15.1 0.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat FumaraseC_C PF10415.4 KUM62659.1 - 0.023 14.7 0.1 0.12 12.4 0.0 2.3 1 0 0 1 1 1 0 Fumarase C C-terminus TPR_8 PF13181.1 KUM62659.1 - 0.041 13.6 5.3 1.2 9.0 0.2 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DNA_ligase_A_N PF04675.9 KUM62659.1 - 0.14 11.9 3.3 0.082 12.7 0.6 1.9 3 0 0 3 3 3 0 DNA ligase N terminus TPR_7 PF13176.1 KUM62659.1 - 0.14 12.0 1.1 3.8 7.5 0.4 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 KUM62659.1 - 0.73 9.8 10.1 0.12 12.3 1.5 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat HAUS-augmin3 PF14932.1 KUM62659.1 - 5.2 6.1 9.0 2.8 7.0 4.1 2.0 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 3 WD40 PF00400.27 KUM62662.1 - 1.5e-60 199.0 25.2 1e-11 44.2 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KUM62662.1 - 5.1e-05 21.6 6.0 0.5 8.4 0.1 3.8 2 1 3 5 5 5 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KUM62662.1 - 0.0034 15.7 0.0 0.66 8.2 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain DUF2683 PF10884.3 KUM62662.1 - 0.16 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2683) EMP24_GP25L PF01105.19 KUM62663.1 - 3.2e-40 137.8 0.0 4.2e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Sdh5 PF03937.11 KUM62663.1 - 7.7e-22 76.7 0.1 1.7e-21 75.6 0.1 1.6 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Piwi PF02171.12 KUM62666.1 - 1.2e-66 224.7 0.0 1.8e-66 224.1 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KUM62666.1 - 9.2e-15 54.1 0.0 1.8e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 KUM62666.1 - 2e-12 46.2 0.1 5.6e-12 44.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) NDUFA12 PF05071.11 KUM62667.1 - 6e-13 49.1 0.5 6e-13 49.1 0.4 2.3 1 1 1 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Nucleo_P87 PF07267.6 KUM62667.1 - 2.2 6.8 7.3 2.7 6.5 5.1 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 zf-CCHC PF00098.18 KUM62668.1 - 1.2e-41 138.6 48.2 5.8e-07 29.1 1.4 7.4 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 KUM62668.1 - 5.1e-11 42.0 44.0 0.0097 15.5 0.1 7.2 7 0 0 7 7 7 5 Zinc knuckle zf-CCHC_3 PF13917.1 KUM62668.1 - 1.1e-10 41.1 35.9 0.054 13.2 0.3 7.1 1 1 6 7 7 7 7 Zinc knuckle zf-CCHC_6 PF15288.1 KUM62668.1 - 6.2e-07 28.9 41.3 0.0061 16.1 0.3 7.2 6 1 1 7 7 7 4 Zinc knuckle zf-CCHC_2 PF13696.1 KUM62668.1 - 7e-05 22.2 25.9 0.017 14.5 0.1 6.2 4 2 2 6 6 6 2 Zinc knuckle Elf1 PF05129.8 KUM62668.1 - 0.2 11.3 34.2 0.15 11.7 2.8 4.2 1 1 2 4 4 4 0 Transcription elongation factor Elf1 like zf-ribbon_3 PF13248.1 KUM62668.1 - 1.6 8.0 31.5 4.7 6.5 0.1 6.8 7 1 0 7 7 7 0 zinc-ribbon domain SelR PF01641.13 KUM62668.1 - 3.1 7.5 17.2 0.055 13.1 3.1 3.2 2 2 0 3 3 3 0 SelR domain zinc_ribbon_5 PF13719.1 KUM62668.1 - 3.1 7.4 35.7 0.95 9.0 0.1 5.6 5 1 0 5 5 5 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KUM62668.1 - 4 7.2 35.9 1 9.1 0.1 5.6 5 1 0 5 5 5 0 zinc-ribbon domain Sugar_tr PF00083.19 KUM62669.1 - 2.3e-105 352.7 25.0 3.2e-105 352.3 17.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM62669.1 - 3.7e-20 71.9 29.9 3.4e-15 55.6 4.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF846 PF05832.7 KUM62670.1 - 2.4e-47 160.2 9.0 2.9e-47 159.9 6.2 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Tic20 PF09685.5 KUM62670.1 - 1.4 8.9 12.1 0.35 10.8 1.3 2.2 2 0 0 2 2 2 0 Tic20-like protein zf-CCHC PF00098.18 KUM62671.1 - 7.2e-27 92.0 51.2 4.8e-07 29.4 2.1 6.5 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_3 PF13917.1 KUM62671.1 - 1.8e-09 37.1 37.8 0.0032 17.1 0.0 6.1 2 1 3 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.1 KUM62671.1 - 4.1e-09 35.9 38.4 0.028 14.0 0.8 6.1 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_2 PF13696.1 KUM62671.1 - 0.089 12.3 0.6 0.089 12.3 0.4 5.6 5 1 1 6 6 6 0 Zinc knuckle RMF PF04957.7 KUM62671.1 - 4.3 7.0 12.5 5.6 6.7 0.3 4.2 2 1 2 4 4 4 0 Ribosome modulation factor Gln-synt_C PF00120.19 KUM62672.1 - 1.5e-20 73.4 0.0 2.1e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 KUM62672.1 - 2.7e-20 71.7 0.0 4.3e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Ada_Zn_binding PF02805.11 KUM62672.1 - 0.23 11.0 1.2 0.45 10.1 0.3 1.8 1 1 1 2 2 2 0 Metal binding domain of Ada Gln-synt_C PF00120.19 KUM62675.1 - 2.4e-27 95.7 0.0 2.6e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain MFS_1 PF07690.11 KUM62676.1 - 3e-35 121.6 48.4 1.1e-29 103.2 22.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 KUM62676.1 - 0.044 13.2 5.3 0.075 12.5 3.2 1.7 1 1 0 1 1 1 0 Ion channel regulatory protein UNC-93 FPN1 PF06963.7 KUM62676.1 - 0.18 10.1 7.0 0.053 11.8 2.2 2.0 2 0 0 2 2 2 0 Ferroportin1 (FPN1) Med1 PF10744.4 KUM62677.1 - 5.8e-97 324.9 0.0 9.1e-97 324.2 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 AMP-binding PF00501.23 KUM62678.1 - 7.8e-68 228.7 0.0 1.1e-67 228.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KUM62678.1 - 0.00027 21.8 0.0 0.00057 20.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Condensation PF00668.15 KUM62678.1 - 0.0035 16.2 0.0 0.006 15.4 0.0 1.3 1 0 0 1 1 1 1 Condensation domain ABC2_membrane PF01061.19 KUM62679.1 - 4.5e-75 251.4 69.4 6.5e-39 133.2 14.7 3.7 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 KUM62679.1 - 2.5e-34 118.5 0.0 4.4e-16 59.4 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 KUM62679.1 - 2.1e-32 110.8 4.8 2.1e-29 101.1 0.0 3.6 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 KUM62679.1 - 8.3e-13 48.2 0.0 2e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 KUM62679.1 - 3.7e-11 42.6 43.8 2.2e-09 36.8 10.6 2.9 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 KUM62679.1 - 7.9e-07 28.6 0.0 8e-05 22.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KUM62679.1 - 3.9e-05 23.7 0.4 0.00066 19.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 KUM62679.1 - 9.1e-05 21.6 0.1 0.0017 17.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KUM62679.1 - 0.00026 20.8 0.2 0.011 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KUM62679.1 - 0.00045 19.6 0.2 0.031 13.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.14 KUM62679.1 - 0.00059 19.1 0.0 0.2 10.8 0.0 3.2 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain cobW PF02492.14 KUM62679.1 - 0.00071 19.0 0.9 0.0037 16.7 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 KUM62679.1 - 0.0015 18.8 0.0 0.06 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KUM62679.1 - 0.003 18.3 0.0 0.43 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KUM62679.1 - 0.0042 16.7 0.1 2.1 8.1 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 KUM62679.1 - 0.006 16.2 0.1 0.68 9.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_21 PF13304.1 KUM62679.1 - 0.023 14.6 0.0 1.2 8.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_22 PF13401.1 KUM62679.1 - 0.058 13.5 0.7 0.49 10.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KUM62679.1 - 0.24 11.6 0.3 2.1 8.6 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_10 PF12846.2 KUM62679.1 - 0.62 9.4 1.7 12 5.2 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain DUF159 PF02586.9 KUM62680.1 - 2.5e-56 190.5 0.1 4.7e-56 189.6 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Mif2_N PF15624.1 KUM62680.1 - 1 9.9 13.2 0.11 13.0 6.0 1.7 2 0 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Sigma70_ner PF04546.8 KUM62682.1 - 2.7 7.5 5.4 5.2 6.6 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Trypan_PARP PF05887.6 KUM62682.1 - 6.5 6.5 11.9 10 5.9 8.2 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Peptidase_S9 PF00326.16 KUM62684.1 - 3.5e-54 183.2 0.4 1.9e-52 177.5 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KUM62684.1 - 4.2e-09 36.2 0.0 7.6e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KUM62684.1 - 5.6e-09 36.2 0.1 1.1e-08 35.2 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 KUM62684.1 - 0.00027 20.5 1.4 0.19 11.4 0.1 3.8 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat COesterase PF00135.23 KUM62684.1 - 0.013 14.2 0.1 0.019 13.6 0.1 1.2 1 0 0 1 1 1 0 Carboxylesterase family Glyco_transf_90 PF05686.7 KUM62685.1 - 5.9e-12 44.9 0.3 0.0015 17.3 0.0 3.9 3 1 0 3 3 3 3 Glycosyl transferase family 90 Vps8 PF12816.2 KUM62686.1 - 5.5e-71 237.8 0.0 9.9e-71 237.0 0.0 1.4 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 KUM62686.1 - 2.2e-07 30.5 0.0 0.0054 16.3 0.0 3.4 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 KUM62686.1 - 0.011 15.5 0.3 0.011 15.5 0.2 2.2 3 0 0 3 3 3 0 Ring finger domain Syntaxin-18_N PF10496.4 KUM62686.1 - 0.062 13.1 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus zf-C3HC4_2 PF13923.1 KUM62686.1 - 0.11 12.5 0.1 0.11 12.5 0.1 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pox_D3 PF04580.8 KUM62686.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirinae D3 protein zf-RING_5 PF14634.1 KUM62686.1 - 0.15 11.8 1.1 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 zinc-RING finger domain Lipase_GDSL_2 PF13472.1 KUM62687.1 - 1.2e-24 87.4 0.0 1.5e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KUM62687.1 - 3.8e-16 59.6 0.0 5.1e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SNase PF00565.12 KUM62688.1 - 9.5e-21 74.0 0.0 1.4e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Voltage_CLC PF00654.15 KUM62689.1 - 5.2e-94 315.1 25.2 2.3e-93 313.0 15.1 2.0 2 0 0 2 2 2 2 Voltage gated chloride channel PqiA PF04403.8 KUM62689.1 - 0.0017 17.9 1.9 0.0072 15.9 0.4 2.6 2 1 1 3 3 3 1 Paraquat-inducible protein A CBS PF00571.23 KUM62689.1 - 0.025 14.3 0.0 0.21 11.4 0.0 2.3 2 0 0 2 2 2 0 CBS domain DHFR_1 PF00186.14 KUM62690.1 - 5.3e-20 71.6 0.0 1.7e-13 50.4 0.0 2.4 2 1 0 2 2 2 2 Dihydrofolate reductase Ribosomal_60s PF00428.14 KUM62690.1 - 0.07 13.5 2.6 2.6 8.4 1.5 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein HK PF02110.10 KUM62691.1 - 6.1e-74 248.2 0.0 1.2e-73 247.3 0.0 1.5 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 KUM62691.1 - 1.5e-59 200.1 2.1 2.3e-59 199.5 1.5 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Carb_kinase PF01256.12 KUM62691.1 - 0.00017 20.9 0.4 0.00048 19.4 0.0 1.8 2 0 0 2 2 2 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 KUM62691.1 - 0.048 12.8 1.8 0.24 10.5 0.0 2.8 2 2 0 3 3 3 0 Phosphomethylpyrimidine kinase eIF-5_eIF-2B PF01873.12 KUM62692.1 - 1e-38 131.8 0.0 1.9e-38 130.9 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 KUM62692.1 - 1.2e-24 86.0 0.2 2.9e-24 84.7 0.1 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon GNAT_acetyltr_2 PF13718.1 KUM62696.1 - 4e-79 264.5 0.0 6.7e-79 263.7 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 KUM62696.1 - 4.2e-66 221.9 0.0 1.3e-65 220.3 0.0 1.8 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 KUM62696.1 - 1e-40 137.3 0.0 2.5e-40 136.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 KUM62696.1 - 1.4e-36 124.5 1.0 4.5e-36 123.0 0.7 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain AAA_19 PF13245.1 KUM62696.1 - 0.012 15.3 0.1 0.15 11.8 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain Acetyltransf_1 PF00583.19 KUM62696.1 - 0.024 14.6 0.0 0.094 12.7 0.0 2.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KUM62696.1 - 0.041 14.0 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ADH_zinc_N PF00107.21 KUM62697.1 - 8.9e-18 64.0 0.0 1.7e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase F-box PF00646.28 KUM62697.1 - 1.5e-06 27.7 0.1 3.3e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KUM62697.1 - 4.8e-05 22.9 0.3 0.00015 21.4 0.2 1.8 1 0 0 1 1 1 1 F-box-like ADH_N PF08240.7 KUM62697.1 - 6e-05 22.7 0.4 0.00016 21.4 0.3 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thioredoxin PF00085.15 KUM62698.1 - 4.9e-30 103.2 0.1 7e-26 89.9 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 KUM62698.1 - 4.1e-08 33.3 1.0 0.00024 21.2 0.2 2.9 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KUM62698.1 - 1.4e-05 25.1 0.0 0.0029 17.7 0.0 3.4 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_6 PF13848.1 KUM62698.1 - 0.00014 21.6 0.0 0.55 10.0 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_3 PF13192.1 KUM62698.1 - 0.00017 21.3 2.3 0.11 12.2 0.0 2.6 3 0 0 3 3 3 2 Thioredoxin domain AhpC-TSA PF00578.16 KUM62698.1 - 0.0018 17.9 0.0 0.0043 16.7 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 KUM62698.1 - 0.0025 17.7 0.0 0.0076 16.2 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 KUM62698.1 - 0.12 11.8 0.1 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin Glutaredoxin PF00462.19 KUM62698.1 - 0.13 12.3 0.0 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Glutaredoxin PI-PLC-X PF00388.14 KUM62699.1 - 0.0092 15.3 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain ADH_zinc_N PF00107.21 KUM62700.1 - 1.5e-09 37.4 0.1 2.5e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM62700.1 - 1.4e-07 31.2 0.0 3.1e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glyco_hydro_16 PF00722.16 KUM62701.1 - 1.5e-11 43.9 0.5 7.4e-11 41.6 0.0 2.3 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 DUF3677 PF12432.3 KUM62702.1 - 0.052 14.0 0.1 0.22 11.9 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3677) Nop14 PF04147.7 KUM62702.1 - 0.45 8.3 3.1 2 6.2 0.0 2.2 2 0 0 2 2 2 0 Nop14-like family HEAT_EZ PF13513.1 KUM62702.1 - 0.65 10.5 6.1 1.5 9.4 0.3 3.8 3 0 0 3 3 3 0 HEAT-like repeat DNA_ligase_A_M PF01068.16 KUM62703.1 - 3.9e-57 192.9 0.2 1.9e-45 154.7 0.1 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KUM62703.1 - 2.9e-55 186.8 0.0 4.8e-55 186.1 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KUM62703.1 - 1.3e-27 96.0 0.0 7.8e-26 90.3 0.0 2.9 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region Isochorismatase PF00857.15 KUM62704.1 - 3.6e-29 101.9 0.0 4.5e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Med22 PF06179.7 KUM62705.1 - 7.7e-20 70.9 0.1 7.7e-20 70.9 0.1 1.5 2 0 0 2 2 2 1 Surfeit locus protein 5 subunit 22 of Mediator complex PG_binding_1 PF01471.13 KUM62705.1 - 0.35 10.8 1.5 3.8 7.5 0.1 2.8 2 2 1 3 3 3 0 Putative peptidoglycan binding domain Apc13p PF05839.6 KUM62706.1 - 0.038 13.9 0.2 14 5.7 0.0 2.7 2 1 0 2 2 2 0 Apc13p protein ADK PF00406.17 KUM62707.1 - 3.1e-34 118.0 0.0 4.7e-20 72.0 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 KUM62707.1 - 1.6e-14 53.2 0.0 2.6e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 KUM62707.1 - 1.5e-05 25.2 0.0 0.00011 22.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KUM62707.1 - 0.00067 20.4 0.0 0.0018 19.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KUM62707.1 - 0.0011 18.8 0.0 0.067 13.0 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 KUM62707.1 - 0.084 12.5 0.1 0.19 11.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 KUM62707.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain adh_short PF00106.20 KUM62708.1 - 6.6e-12 45.6 0.1 1.2e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM62708.1 - 0.0014 18.2 0.1 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM62708.1 - 0.033 13.6 0.0 0.076 12.4 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.5 KUM62709.1 - 2.6e-58 196.6 0.2 5.4e-58 195.6 0.1 1.6 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KUM62709.1 - 5.5e-45 153.2 0.2 1e-44 152.4 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.20 KUM62709.1 - 1.8e-06 28.0 0.1 3.6e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Shikimate_DH PF01488.15 KUM62709.1 - 0.045 13.8 0.0 0.087 12.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ATP-synt PF00231.14 KUM62710.1 - 5.6e-68 229.4 7.7 6.4e-68 229.2 5.3 1.0 1 0 0 1 1 1 1 ATP synthase Beta-Casp PF10996.3 KUM62710.1 - 0.085 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Beta-Casp domain DnaJ PF00226.26 KUM62711.1 - 4.2e-18 64.8 0.2 1e-17 63.5 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain Epimerase PF01370.16 KUM62712.1 - 6e-20 71.6 0.0 8.5e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KUM62712.1 - 4.4e-07 29.0 0.0 6.6e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 KUM62712.1 - 8.6e-07 27.9 0.0 4.6e-06 25.5 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KUM62712.1 - 2.3e-06 27.6 0.0 6.2e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KUM62712.1 - 4.4e-05 23.5 0.0 0.00021 21.3 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KUM62712.1 - 0.003 17.2 0.0 0.033 13.8 0.0 2.1 2 0 0 2 2 2 1 KR domain Ldh_1_N PF00056.18 KUM62712.1 - 0.0062 16.3 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KUM62712.1 - 0.067 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Topoisom_I_N PF02919.10 KUM62713.1 - 6.5e-96 319.7 2.8 6.5e-96 319.7 1.9 3.8 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 KUM62713.1 - 2.1e-81 272.4 8.0 2.1e-81 272.4 5.5 2.6 3 1 1 4 4 4 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 KUM62713.1 - 5.4e-33 112.4 0.6 2.1e-32 110.5 0.4 2.1 1 0 0 1 1 1 1 C-terminal topoisomerase domain RolB_RolC PF02027.12 KUM62713.1 - 0.025 13.7 0.1 0.051 12.7 0.0 1.4 1 0 0 1 1 1 0 RolB/RolC glucosidase family Ribosomal_S15 PF00312.17 KUM62713.1 - 0.16 11.7 6.3 0.13 11.9 1.1 2.7 2 0 0 2 2 2 0 Ribosomal protein S15 Calpain_III PF01067.17 KUM62714.1 - 1.7e-23 82.8 0.0 6.8e-18 64.7 0.0 2.8 2 0 0 2 2 2 2 Calpain large subunit, domain III Peptidase_C2 PF00648.16 KUM62714.1 - 8.1e-23 80.8 0.0 1.4e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease MIT PF04212.13 KUM62714.1 - 9.3e-06 25.4 7.2 1.5e-05 24.7 5.0 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF605 PF04652.11 KUM62715.1 - 7.2e-97 325.1 1.7 8.8e-97 324.8 1.2 1.1 1 0 0 1 1 1 1 Vta1 like Mito_carr PF00153.22 KUM62717.1 - 2.1e-54 181.2 1.7 4.3e-19 68.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein GYF PF02213.11 KUM62718.1 - 3.5e-12 45.7 0.6 6.9e-12 44.7 0.4 1.5 1 0 0 1 1 1 1 GYF domain NusB PF01029.13 KUM62718.1 - 3.5 7.6 6.5 6.1 6.8 0.8 2.5 2 0 0 2 2 2 0 NusB family UFD1 PF03152.9 KUM62719.1 - 2.4e-75 251.5 0.0 3e-75 251.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 KUM62719.1 - 0.00091 18.8 0.0 0.0089 15.6 0.0 2.2 1 1 1 2 2 2 1 Cell division protein 48 (CDC48), domain 2 DUF829 PF05705.9 KUM62720.1 - 2.2e-30 106.1 0.0 2.5e-30 105.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF4246 PF14033.1 KUM62721.1 - 7.8e-163 542.6 0.1 1.1e-162 542.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) RNA_pol_Rpb2_6 PF00562.23 KUM62722.1 - 5.3e-116 387.5 0.1 5.3e-116 387.5 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KUM62722.1 - 4.4e-54 182.4 0.8 4.4e-54 182.4 0.5 1.7 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 KUM62722.1 - 1e-29 102.6 0.3 9.4e-29 99.5 0.1 2.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 KUM62722.1 - 1.7e-28 99.3 3.5 3.4e-28 98.3 2.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 KUM62722.1 - 7.5e-22 76.9 2.4 1.1e-21 76.3 0.5 2.3 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 KUM62722.1 - 4e-20 71.3 0.2 3.1e-19 68.4 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 KUM62722.1 - 2.8e-14 52.8 0.4 5.8e-14 51.8 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 PUF PF00806.14 KUM62724.1 - 7.4e-60 195.1 10.4 2.5e-07 29.7 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat MgtE_N PF03448.12 KUM62724.1 - 0.062 13.6 0.0 0.21 11.9 0.0 1.9 1 0 0 1 1 1 0 MgtE intracellular N domain Rootletin PF15035.1 KUM62725.1 - 0.0036 17.3 7.8 0.0036 17.3 5.4 6.4 2 2 3 7 7 7 1 Ciliary rootlet component, centrosome cohesion Reo_sigmaC PF04582.7 KUM62725.1 - 0.018 14.2 45.6 0.044 12.9 1.6 5.7 3 2 2 6 6 6 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 KUM62725.1 - 0.018 14.8 59.5 0.25 11.1 2.1 7.6 2 2 4 8 8 8 0 Baculovirus polyhedron envelope protein, PEP, C terminus Hemerythrin PF01814.18 KUM62725.1 - 0.47 10.6 12.8 3.3 7.8 1.3 5.5 3 1 2 5 5 5 0 Hemerythrin HHE cation binding domain AAA_13 PF13166.1 KUM62725.1 - 0.54 8.6 71.3 0.004 15.7 5.5 5.2 2 1 2 5 5 5 0 AAA domain Vps54 PF07928.7 KUM62725.1 - 0.55 10.3 5.3 11 6.0 0.0 4.0 4 0 0 4 4 4 0 Vps54-like protein DUF4252 PF14060.1 KUM62725.1 - 1.8 8.0 13.0 2.6 7.5 1.5 4.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4252) TIP49 PF06068.8 KUM62726.1 - 2.2e-173 576.5 4.7 2.5e-173 576.3 3.3 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KUM62726.1 - 3.3e-09 37.0 0.8 5.8e-06 26.5 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KUM62726.1 - 5e-08 32.2 1.4 3.9e-05 22.8 0.0 2.6 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 KUM62726.1 - 6.2e-06 25.2 0.4 1.1e-05 24.4 0.3 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 KUM62726.1 - 4.9e-05 23.4 0.0 0.00069 19.6 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KUM62726.1 - 0.00013 22.1 0.0 0.12 12.5 0.0 2.5 1 1 1 2 2 2 2 AAA domain Mg_chelatase PF01078.16 KUM62726.1 - 0.00095 18.3 0.7 0.0099 15.0 0.3 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 KUM62726.1 - 0.0018 18.1 0.0 2.1 8.2 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 KUM62726.1 - 0.0083 15.5 0.1 0.021 14.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 KUM62726.1 - 0.01 15.3 0.0 5.3 6.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.1 KUM62726.1 - 0.017 14.8 0.7 0.096 12.4 0.2 2.3 1 1 1 2 2 2 0 Part of AAA domain AAA_5 PF07728.9 KUM62726.1 - 0.024 14.3 0.1 0.7 9.6 0.0 2.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Parvo_NS1 PF01057.12 KUM62726.1 - 0.051 12.4 0.0 0.082 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 KUM62726.1 - 0.079 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KUM62726.1 - 0.093 12.2 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Abp2 PF09441.5 KUM62728.1 - 9.2e-82 273.1 0.0 1.6e-81 272.4 0.0 1.3 1 0 0 1 1 1 1 ARS binding protein 2 TAF1D PF15333.1 KUM62728.1 - 0.077 12.7 0.8 3.1 7.5 0.0 2.3 2 0 0 2 2 2 0 TATA box-binding protein-associated factor 1D Surfac_D-trimer PF09006.6 KUM62728.1 - 0.18 11.5 2.0 0.37 10.5 1.4 1.5 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation Myb_DNA-binding PF00249.26 KUM62730.1 - 0.028 14.4 0.1 0.23 11.5 0.0 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain HTH_11 PF08279.7 KUM62730.1 - 0.044 13.4 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 HTH domain HTH_5 PF01022.15 KUM62730.1 - 0.047 13.3 0.1 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Sigma70_r4_2 PF08281.7 KUM62730.1 - 0.074 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_24 PF13412.1 KUM62730.1 - 0.079 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Filaggrin PF03516.8 KUM62730.1 - 0.11 12.9 0.8 0.32 11.4 0.6 1.7 1 0 0 1 1 1 0 Filaggrin Menin PF05053.8 KUM62730.1 - 0.12 10.5 1.3 0.12 10.4 0.9 1.1 1 0 0 1 1 1 0 Menin HTH_20 PF12840.2 KUM62730.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain PBP1_TM PF14812.1 KUM62730.1 - 0.35 11.2 5.2 0.56 10.5 3.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Trypsin_2 PF13365.1 KUM62731.1 - 0.067 13.1 0.0 0.081 12.9 0.0 1.2 1 0 0 1 1 1 0 Trypsin-like peptidase domain Pox_Ag35 PF03286.9 KUM62731.1 - 1.1 8.7 7.9 1.3 8.5 5.5 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein F-box-like PF12937.2 KUM62732.1 - 0.00059 19.4 1.4 0.0015 18.1 1.0 1.7 1 0 0 1 1 1 1 F-box-like DHC_N2 PF08393.8 KUM62732.1 - 0.12 10.8 0.1 0.2 10.1 0.1 1.3 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 LRR_4 PF12799.2 KUM62732.1 - 0.13 11.8 7.3 3 7.5 0.3 3.5 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KUM62732.1 - 0.23 11.2 8.4 5.1 6.9 0.1 3.4 1 1 2 3 3 3 0 Leucine rich repeat LRR_7 PF13504.1 KUM62732.1 - 4.1 8.0 8.4 3.6 8.2 0.2 3.9 3 0 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.28 KUM62732.1 - 8.9 6.7 7.3 3.6 7.9 0.6 3.2 2 0 0 2 2 2 0 Leucine Rich Repeat WW PF00397.21 KUM62733.1 - 0.00019 21.2 3.8 0.00087 19.1 2.6 2.3 1 0 0 1 1 1 1 WW domain ORC5_C PF14630.1 KUM62735.1 - 1.6e-92 309.8 0.0 2e-92 309.4 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 KUM62735.1 - 6e-15 55.7 1.7 7.6e-15 55.3 0.2 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KUM62735.1 - 0.0081 16.3 0.0 0.024 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 KUM62735.1 - 0.074 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain 7tm_1 PF00001.16 KUM62736.1 - 4.2e-09 35.9 4.9 5.9e-09 35.4 3.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.3 KUM62736.1 - 4.4e-09 36.1 10.3 1.1e-08 34.8 7.1 1.6 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.6 KUM62736.1 - 4.3e-08 32.4 10.4 1.1e-06 27.7 5.0 2.0 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 KUM62736.1 - 0.00013 21.1 5.3 0.00024 20.2 3.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7TM_GPCR_Srsx PF10320.4 KUM62736.1 - 0.00013 21.1 8.4 0.00019 20.6 5.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx WBP-1 PF11669.3 KUM62736.1 - 0.0052 16.8 0.1 0.018 15.1 0.0 1.9 2 0 0 2 2 2 1 WW domain-binding protein 1 DUF1849 PF08904.6 KUM62736.1 - 0.015 14.6 0.4 0.022 14.1 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1849) Pex14_N PF04695.8 KUM62736.1 - 0.081 12.9 2.4 0.13 12.3 1.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region F-box-like_2 PF13013.1 KUM62737.1 - 0.035 13.8 0.0 0.92 9.2 0.0 2.8 2 1 1 3 3 3 0 F-box-like domain ABC_tran PF00005.22 KUM62738.1 - 2.2e-25 89.5 0.0 4.5e-25 88.5 0.0 1.5 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 KUM62738.1 - 1.7e-17 63.7 3.2 1.8e-17 63.6 1.7 1.4 1 1 0 2 2 2 1 ABC transporter transmembrane region AAA_25 PF13481.1 KUM62738.1 - 0.013 14.9 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KUM62738.1 - 0.018 15.5 0.1 0.038 14.5 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 KUM62738.1 - 0.028 14.3 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 KUM62738.1 - 0.029 13.8 0.1 0.066 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KUM62738.1 - 0.081 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_21 PF13304.1 KUM62738.1 - 0.084 12.8 0.0 0.18 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 KUM62738.1 - 0.11 11.1 0.1 0.17 10.4 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.12 KUM62738.1 - 0.11 12.2 0.2 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 ArgK PF03308.11 KUM62738.1 - 0.12 11.0 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 ArgK protein E1-E2_ATPase PF00122.15 KUM62740.1 - 1.7e-58 197.3 8.3 4.1e-58 196.1 5.8 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KUM62740.1 - 3.4e-21 76.6 0.0 1.6e-20 74.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KUM62740.1 - 2.6e-13 50.5 0.0 5.4e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KUM62740.1 - 2.1e-11 43.1 0.0 6.7e-11 41.5 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KUM62740.1 - 0.002 17.7 0.1 0.0049 16.4 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ninjurin PF04923.7 KUM62740.1 - 2.6 7.7 4.9 0.5 10.1 0.5 1.9 2 0 0 2 2 2 0 Ninjurin Peptidase_M20 PF01546.23 KUM62742.1 - 2.2e-07 30.5 0.2 3.3e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KUM62742.1 - 3.6e-05 23.4 0.0 0.00011 21.9 0.0 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain Abhydrolase_6 PF12697.2 KUM62743.1 - 1.2e-32 113.6 0.0 2.5e-32 112.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM62743.1 - 1.5e-22 80.2 0.0 2.5e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KUM62743.1 - 2.1e-17 63.1 0.0 5.8e-17 61.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KUM62743.1 - 5e-10 39.3 0.0 6.6e-10 38.9 0.0 1.3 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 KUM62743.1 - 1.1e-07 31.6 0.0 1.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 KUM62743.1 - 4.4e-07 30.3 0.0 1.6e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain Chlorophyllase PF07224.6 KUM62743.1 - 0.00064 18.6 0.0 0.0018 17.1 0.0 1.7 2 0 0 2 2 2 1 Chlorophyllase Esterase PF00756.15 KUM62743.1 - 0.00097 18.6 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.3 KUM62743.1 - 0.0013 18.5 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Lipase_3 PF01764.20 KUM62743.1 - 0.002 17.7 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Ndr PF03096.9 KUM62743.1 - 0.0035 15.8 0.0 0.0072 14.8 0.0 1.5 1 0 0 1 1 1 1 Ndr family Ser_hydrolase PF06821.8 KUM62743.1 - 0.0082 15.7 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 Serine hydrolase DUF2305 PF10230.4 KUM62743.1 - 0.0088 15.4 0.0 0.037 13.4 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Chlorophyllase2 PF12740.2 KUM62743.1 - 0.0089 14.9 0.0 0.052 12.4 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase enzyme DUF2974 PF11187.3 KUM62743.1 - 0.071 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DLH PF01738.13 KUM62743.1 - 0.081 12.1 0.3 4.8 6.4 0.2 2.7 2 1 0 2 2 2 0 Dienelactone hydrolase family DUF2048 PF09752.4 KUM62743.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) LCAT PF02450.10 KUM62743.1 - 0.17 10.8 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase EHN PF06441.7 KUM62744.1 - 3.4e-38 130.0 2.1 9.3e-38 128.5 0.1 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KUM62744.1 - 9.3e-10 38.7 2.6 1.7e-09 37.9 1.1 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM62744.1 - 1.8e-06 27.7 0.1 4.3e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF3224 PF11528.3 KUM62745.1 - 0.059 12.8 0.0 0.95 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3224) DUF515 PF04415.7 KUM62745.1 - 6.6 4.8 6.5 11 4.1 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) FtsK_SpoIIIE PF01580.13 KUM62746.1 - 0.00029 20.3 0.0 0.00035 20.1 0.0 1.1 1 0 0 1 1 1 1 FtsK/SpoIIIE family B12-binding PF02310.14 KUM62746.1 - 0.0034 17.2 0.1 0.0048 16.7 0.0 1.2 1 0 0 1 1 1 1 B12 binding domain FAA_hydrolase PF01557.13 KUM62747.1 - 2.9e-50 170.7 0.0 4e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family MFS_1 PF07690.11 KUM62748.1 - 1.8e-40 138.7 26.9 2.6e-40 138.2 18.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM62748.1 - 1.3e-14 53.6 30.8 6.9e-14 51.2 4.9 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter TRI12 PF06609.8 KUM62748.1 - 8.7e-07 27.5 3.6 1e-05 23.9 1.5 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Gly-zipper_YMGG PF13441.1 KUM62748.1 - 0.13 11.8 1.7 1.7 8.1 1.2 2.5 1 1 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.1 KUM62748.1 - 0.2 11.3 2.5 7.6 6.2 0.4 2.8 2 0 0 2 2 2 0 Glycine zipper zf-C2H2 PF00096.21 KUM62749.1 - 8.8e-09 35.2 11.5 2.1e-05 24.5 0.3 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KUM62749.1 - 3.7e-06 26.8 11.3 0.012 15.8 3.0 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KUM62749.1 - 8.5e-06 25.8 5.8 8.5e-06 25.8 4.1 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KUM62749.1 - 2.1e-05 24.5 2.1 0.12 12.5 0.0 2.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KUM62749.1 - 0.00043 20.0 6.3 0.089 12.7 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KUM62749.1 - 0.00053 20.0 1.5 0.065 13.4 0.1 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type C1_4 PF07975.7 KUM62749.1 - 0.037 14.0 2.2 0.069 13.1 1.6 1.4 1 0 0 1 1 1 0 TFIIH C1-like domain zf-Paramyx-P PF13008.2 KUM62749.1 - 0.44 9.7 3.0 0.9 8.7 2.0 1.4 1 0 0 1 1 1 0 Zinc-binding domain of Paramyxoviridae V protein zf-met2 PF12907.2 KUM62749.1 - 0.49 10.4 2.8 16 5.5 0.1 2.8 3 0 0 3 3 3 0 Zinc-binding RIG-I_C-RD PF11648.3 KUM62749.1 - 0.59 10.0 4.2 0.79 9.6 1.0 2.0 1 1 1 2 2 2 0 C-terminal domain of RIG-I zf-BED PF02892.10 KUM62749.1 - 5.5 6.8 7.2 8.2 6.2 2.2 2.5 1 1 1 2 2 2 0 BED zinc finger Fungal_trans PF04082.13 KUM62750.1 - 4.7e-07 28.9 0.6 4.7e-07 28.9 0.4 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Hepatitis_core PF00906.15 KUM62751.1 - 0.58 9.8 5.9 1 9.0 4.1 1.4 1 0 0 1 1 1 0 Hepatitis core antigen ORC6 PF05460.8 KUM62752.1 - 0.026 13.6 6.0 0.028 13.5 4.2 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Cys_Met_Meta_PP PF01053.15 KUM62753.1 - 2.3e-140 467.2 0.1 2.6e-140 467.1 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KUM62753.1 - 4.7e-09 35.6 0.1 6.8e-09 35.1 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KUM62753.1 - 3.6e-08 32.8 0.3 7e-08 31.9 0.2 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 KUM62753.1 - 2.2e-07 29.9 1.1 3.9e-07 29.1 0.3 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KUM62753.1 - 1.4e-06 27.6 0.2 2.5e-06 26.8 0.2 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase RNA_pol_Rbc25 PF08292.7 KUM62754.1 - 1.1e-29 103.1 0.1 1.7e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 KUM62754.1 - 2.6e-14 53.0 0.0 4.2e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 MFS_1 PF07690.11 KUM62755.1 - 4.3e-40 137.5 52.3 4.3e-40 137.5 36.3 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 KUM62756.1 - 1.8e-13 49.8 1.6 1.3e-12 47.0 1.1 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_1 PF00583.19 KUM62757.1 - 1.2e-10 41.2 0.0 1.9e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KUM62757.1 - 6.7e-08 32.1 0.0 1.1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KUM62757.1 - 3.1e-05 24.0 0.0 4.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KUM62757.1 - 0.00053 19.8 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 KUM62757.1 - 0.014 15.5 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KUM62757.1 - 0.015 15.4 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KUM62757.1 - 0.021 14.7 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KUM62757.1 - 0.041 13.7 0.0 0.11 12.3 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain TFIIA_gamma_N PF02268.11 KUM62759.1 - 0.067 12.7 0.0 5.1 6.7 0.1 3.1 3 0 0 3 3 3 0 Transcription initiation factor IIA, gamma subunit, helical domain DAO PF01266.19 KUM62760.1 - 1.9e-26 92.8 0.1 2.4e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KUM62760.1 - 0.00011 22.2 0.0 0.0003 20.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KUM62760.1 - 0.00023 20.3 0.3 0.00063 18.8 0.0 1.9 2 0 0 2 2 2 1 Thi4 family OTU PF02338.14 KUM62761.1 - 4.3e-14 53.1 0.2 1.3e-13 51.6 0.1 1.8 1 1 0 1 1 1 1 OTU-like cysteine protease CUE PF02845.11 KUM62761.1 - 0.00066 19.0 0.0 0.0025 17.2 0.0 2.0 3 0 0 3 3 3 1 CUE domain Peptidase_C65 PF10275.4 KUM62761.1 - 0.0074 15.6 0.1 4.4 6.5 0.0 2.3 1 1 0 2 2 2 2 Peptidase C65 Otubain UBA_4 PF14555.1 KUM62761.1 - 0.11 11.9 0.0 0.31 10.6 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain GATase PF00117.23 KUM62762.1 - 1e-10 41.3 0.0 1.3e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 KUM62762.1 - 0.016 14.8 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain COPI_assoc PF08507.5 KUM62763.1 - 1.3e-42 144.8 5.4 1.4e-42 144.6 3.8 1.0 1 0 0 1 1 1 1 COPI associated protein DUF2636 PF11120.3 KUM62763.1 - 0.16 11.4 0.7 7.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2636) Cytochrom_B558a PF05038.8 KUM62763.1 - 0.2 11.2 1.6 0.36 10.4 1.1 1.4 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Bax1-I PF01027.15 KUM62763.1 - 1.6 8.2 12.3 2 7.9 8.2 1.4 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF2892 PF11127.3 KUM62763.1 - 5.8 6.8 15.0 0.81 9.5 3.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2892) Cg6151-P PF10233.4 KUM62763.1 - 7.5 6.5 7.5 33 4.5 3.5 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein CG6151-P MFS_1 PF07690.11 KUM62764.1 - 1.8e-37 128.9 22.6 2.8e-35 121.6 13.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KUM62764.1 - 2.3e-11 42.7 14.1 2.3e-07 29.5 0.5 2.3 2 1 0 2 2 2 2 MFS/sugar transport protein Mem_trans PF03547.13 KUM62764.1 - 4.1e-05 22.0 0.1 7e-05 21.2 0.1 1.4 1 0 0 1 1 1 1 Membrane transport protein DUF2613 PF11021.3 KUM62764.1 - 2.6 7.8 4.7 1.6 8.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) MFS_3 PF05977.8 KUM62764.1 - 3.6 5.5 18.6 0.059 11.4 1.9 2.4 3 0 0 3 3 3 0 Transmembrane secretion effector DUF3716 PF12511.3 KUM62765.1 - 1.4e-10 40.5 2.4 2.2e-10 39.9 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) MtN3_slv PF03083.11 KUM62767.1 - 0.041 13.7 0.2 0.041 13.7 0.2 2.2 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange p450 PF00067.17 KUM62769.1 - 3.4e-46 157.7 0.0 3.8e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1469 PF07332.6 KUM62770.1 - 0.5 10.0 8.0 0.065 12.9 2.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) FAD_binding_3 PF01494.14 KUM62771.1 - 8.4e-16 57.9 0.7 6.4e-13 48.4 0.5 3.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KUM62771.1 - 3.6e-06 26.9 0.1 9.8e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KUM62771.1 - 0.0012 19.2 0.0 0.19 12.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KUM62771.1 - 0.002 17.1 0.1 0.021 13.7 0.0 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KUM62771.1 - 0.026 13.6 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 KUM62771.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM62771.1 - 0.11 12.2 0.1 0.64 9.7 0.0 2.3 2 1 0 2 2 2 0 FAD-NAD(P)-binding Acyltransferase PF01553.16 KUM62773.1 - 1.5e-16 60.0 0.0 3.1e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase HTH_Crp_2 PF13545.1 KUM62773.1 - 0.099 12.4 0.0 4.8 7.0 0.0 2.9 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Pantoate_ligase PF02569.10 KUM62774.1 - 3.3e-80 268.8 0.0 2.1e-79 266.2 0.0 1.9 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase Cellulase PF00150.13 KUM62775.1 - 1.3e-17 63.9 6.1 1.8e-17 63.5 4.2 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 KUM62775.1 - 0.00024 20.3 0.2 0.036 13.1 0.1 2.1 2 0 0 2 2 2 2 Beta-galactosidase Glyco_hydro_10 PF00331.15 KUM62775.1 - 0.0025 16.9 0.8 0.018 14.0 0.0 2.5 3 0 0 3 3 3 1 Glycosyl hydrolase family 10 Cellulase-like PF12876.2 KUM62775.1 - 0.012 16.0 0.0 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 Sugar-binding cellulase-like Glyco_hydro_2_C PF02836.12 KUM62775.1 - 0.016 14.1 1.5 0.018 13.9 0.3 1.7 2 1 0 2 2 2 0 Glycosyl hydrolases family 2, TIM barrel domain DUF2255 PF10012.4 KUM62775.1 - 0.046 13.6 0.2 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) Filament PF00038.16 KUM62777.1 - 3.2e-05 23.5 68.5 5.3e-05 22.8 38.8 2.9 1 1 2 3 3 3 1 Intermediate filament protein Reo_sigmaC PF04582.7 KUM62777.1 - 0.24 10.5 22.5 0.2 10.7 3.6 3.9 1 1 3 4 4 4 0 Reovirus sigma C capsid protein DUF3584 PF12128.3 KUM62777.1 - 0.83 6.9 71.3 0.026 11.8 6.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) ATG16 PF08614.6 KUM62777.1 - 1.1 9.0 67.9 7.9 6.2 19.0 4.0 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) IncA PF04156.9 KUM62777.1 - 2.3 7.7 81.2 5.7 6.4 18.3 3.6 1 1 2 3 3 3 0 IncA protein Baculo_PEP_C PF04513.7 KUM62777.1 - 2.7 7.8 24.8 1.1 9.1 3.8 4.5 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DNApol3-delta_C PF09115.5 KUM62778.1 - 0.03 14.3 0.0 0.049 13.6 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit, C terminal Methyltransf_16 PF10294.4 KUM62779.1 - 0.0012 18.3 0.0 0.68 9.3 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase DEAD PF00270.24 KUM62781.1 - 7.4e-42 142.7 0.1 1.1e-41 142.1 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM62781.1 - 1.7e-18 66.2 0.0 4.4e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KUM62781.1 - 1.8e-18 65.8 0.0 3.5e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 KUM62781.1 - 0.00023 21.0 0.7 0.0015 18.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit FAM176 PF14851.1 KUM62781.1 - 0.031 13.9 2.9 0.38 10.4 0.2 2.9 2 0 0 2 2 2 0 FAM176 family Glutenin_hmw PF03157.8 KUM62781.1 - 0.24 9.6 0.8 0.34 9.1 0.5 1.1 1 0 0 1 1 1 0 High molecular weight glutenin subunit WD40 PF00400.27 KUM62782.1 - 7.3e-20 70.0 12.0 0.0033 17.2 0.1 7.7 8 1 0 8 8 8 5 WD domain, G-beta repeat Nitroreductase PF00881.19 KUM62783.1 - 0.017 14.9 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Nitroreductase family Nitroreductase PF00881.19 KUM62784.1 - 7.4e-06 25.8 0.0 9.1e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family DUF2294 PF10057.4 KUM62784.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2294) ketoacyl-synt PF00109.21 KUM62786.1 - 7.7e-55 186.1 1.0 9.5e-55 185.8 0.7 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.18 KUM62786.1 - 9.7e-05 21.4 0.1 0.00014 20.9 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain MFS_1 PF07690.11 KUM62787.1 - 1.6e-31 109.3 33.3 1.6e-31 109.3 23.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily FA_desaturase PF00487.19 KUM62787.1 - 0.018 14.5 9.5 0.047 13.1 0.4 2.9 2 1 0 2 2 2 0 Fatty acid desaturase MFS_1 PF07690.11 KUM62788.1 - 2e-26 92.5 47.8 2e-26 92.5 33.1 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily GATA PF00320.22 KUM62789.1 - 2.8e-30 103.3 17.9 7.7e-16 57.1 4.3 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 KUM62789.1 - 1.1e-05 24.6 1.9 0.0062 15.8 0.0 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding zf-ribbon_3 PF13248.1 KUM62789.1 - 0.00078 18.5 7.3 0.073 12.3 0.3 3.0 2 1 0 2 2 2 2 zinc-ribbon domain Auto_anti-p27 PF06677.7 KUM62789.1 - 0.0063 16.2 5.4 0.072 12.8 0.3 2.5 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Ribosomal_S27e PF01667.12 KUM62789.1 - 0.038 13.5 0.8 1.9 8.1 0.1 2.5 2 0 0 2 2 2 0 Ribosomal protein S27 Zn-ribbon_8 PF09723.5 KUM62789.1 - 0.056 13.3 2.7 1.6 8.7 0.2 2.7 2 0 0 2 2 2 0 Zinc ribbon domain eIF-5_eIF-2B PF01873.12 KUM62789.1 - 0.08 12.5 4.1 2.5 7.8 0.2 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 ArfGap PF01412.13 KUM62789.1 - 0.31 10.8 4.2 0.78 9.5 0.1 2.3 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf PGA_cap PF09587.5 KUM62790.1 - 4.2e-63 213.0 0.1 8.5e-63 212.0 0.1 1.5 1 1 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap Methyltransf_2 PF00891.13 KUM62791.1 - 6.4e-29 100.8 0.0 8.6e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 KUM62791.1 - 0.033 13.9 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KUM62791.1 - 0.084 13.4 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FAD_binding_3 PF01494.14 KUM62792.1 - 7.8e-09 35.0 0.0 0.00026 20.1 0.0 3.0 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 KUM62792.1 - 4.3e-08 33.0 1.0 1.5e-07 31.3 0.4 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KUM62792.1 - 1.6e-05 23.9 0.7 0.00019 20.4 0.5 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KUM62792.1 - 0.00025 20.9 0.5 0.0038 17.1 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KUM62792.1 - 0.00067 18.6 2.1 0.00094 18.1 1.5 1.2 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 KUM62792.1 - 0.0025 16.5 0.6 1.1 7.8 0.7 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.22 KUM62792.1 - 0.0053 17.1 1.0 0.013 15.8 0.7 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KUM62792.1 - 0.024 13.7 0.2 2.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase HI0933_like PF03486.9 KUM62792.1 - 0.027 12.9 0.6 0.04 12.3 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.16 KUM62792.1 - 0.057 12.9 0.4 0.099 12.2 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 KUM62792.1 - 0.059 12.4 0.1 0.097 11.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 KUM62792.1 - 0.094 12.4 0.4 0.47 10.2 0.2 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 KUM62792.1 - 0.18 11.4 0.3 0.43 10.2 0.2 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 KUM62792.1 - 0.23 10.2 1.4 0.36 9.6 1.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A MFS_1 PF07690.11 KUM62794.1 - 1.3e-33 116.2 35.3 6.7e-33 113.8 25.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.4 KUM62794.1 - 0.01 16.2 1.8 0.068 13.5 1.0 2.5 2 1 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF2762 PF10960.3 KUM62794.1 - 0.012 15.3 0.0 0.036 13.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) PMP1_2 PF08114.6 KUM62794.1 - 0.1 12.1 0.3 0.1 12.1 0.2 2.9 2 0 0 2 2 2 0 ATPase proteolipid family Pkinase PF00069.20 KUM62795.1 - 1.4e-67 227.5 0.0 1.7e-67 227.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM62795.1 - 1.1e-31 109.9 0.0 1.4e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase 2-Hacid_dh PF00389.25 KUM62797.1 - 2.8e-30 104.4 0.0 3.4e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 2-Hacid_dh_C PF02826.14 KUM62797.1 - 0.045 12.9 0.0 0.087 11.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KUM62798.1 - 4.8e-34 117.0 0.0 7.8e-34 116.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KUM62798.1 - 0.0033 16.8 0.0 0.0052 16.2 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.20 KUM62798.1 - 0.0042 16.5 0.0 0.0091 15.4 0.0 1.6 1 0 0 1 1 1 1 ACT domain P5-ATPase PF12409.3 KUM62799.1 - 2e-39 134.1 0.1 3.3e-38 130.1 0.0 2.3 2 0 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.15 KUM62799.1 - 2.3e-14 52.9 0.0 4.7e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.21 KUM62799.1 - 0.0014 18.0 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus NAP PF00956.13 KUM62800.1 - 1.6e-86 289.4 8.8 1.6e-86 289.4 6.1 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Sigma70_ner PF04546.8 KUM62800.1 - 0.0063 16.1 2.9 0.0063 16.1 2.0 2.8 2 1 0 2 2 2 1 Sigma-70, non-essential region Cation_ATPase_C PF00689.16 KUM62801.1 - 5.6e-08 32.5 10.6 7.6e-08 32.0 7.4 1.1 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus DUF4191 PF13829.1 KUM62801.1 - 0.14 11.2 0.1 0.14 11.2 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF1129 PF06570.6 KUM62801.1 - 2.1 7.6 5.4 3 7.1 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) HAD PF12710.2 KUM62802.1 - 6.8e-32 111.1 0.0 1.1e-31 110.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KUM62802.1 - 2.4e-19 70.6 0.0 4e-18 66.6 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KUM62802.1 - 2.5e-07 29.9 0.8 4e-07 29.3 0.6 1.2 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KUM62802.1 - 0.00054 19.8 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Fork_head PF00250.13 KUM62803.1 - 9.4e-37 124.9 0.3 1.6e-36 124.2 0.2 1.4 1 0 0 1 1 1 1 Fork head domain G10 PF01125.12 KUM62804.1 - 2.1e-65 218.7 4.2 2.3e-65 218.5 2.9 1.0 1 0 0 1 1 1 1 G10 protein AA_kinase PF00696.23 KUM62805.1 - 7.5e-39 133.7 0.0 1.2e-38 133.0 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.1 KUM62805.1 - 1.3e-11 43.8 1.4 2.6e-09 36.4 0.1 2.4 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 KUM62805.1 - 7e-11 41.3 1.1 1.6e-08 33.8 0.1 3.3 3 0 0 3 3 3 2 ACT domain zf-Tim10_DDP PF02953.10 KUM62806.1 - 1.4e-21 75.5 3.2 1.8e-21 75.2 2.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Latrotoxin_C PF15658.1 KUM62806.1 - 0.024 14.4 0.1 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 Latrotoxin C-terminal domain FANCI_HD2 PF14680.1 KUM62806.1 - 0.044 12.8 1.0 0.05 12.7 0.7 1.1 1 0 0 1 1 1 0 FANCI helical domain 2 AAA_18 PF13238.1 KUM62808.1 - 2.7e-26 92.3 0.3 4.8e-26 91.5 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KUM62808.1 - 1.6e-13 51.5 0.4 2.5e-13 50.9 0.3 1.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KUM62808.1 - 0.00018 21.7 0.0 0.0003 20.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KUM62808.1 - 0.0021 17.9 0.0 0.042 13.7 0.0 2.3 1 1 1 2 2 2 1 AAA domain ADK PF00406.17 KUM62808.1 - 0.0029 17.4 0.0 0.019 14.8 0.0 2.0 2 0 0 2 2 2 1 Adenylate kinase RNA_helicase PF00910.17 KUM62808.1 - 0.0036 17.4 0.0 0.0065 16.6 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.1 KUM62808.1 - 0.0043 17.0 0.0 0.0078 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KUM62808.1 - 0.0044 17.0 0.0 0.0096 15.9 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KUM62808.1 - 0.0087 16.2 0.0 0.016 15.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KUM62808.1 - 0.0096 15.8 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 KUM62808.1 - 0.012 15.3 0.2 0.025 14.2 0.1 1.6 2 0 0 2 2 2 0 NTPase KTI12 PF08433.5 KUM62808.1 - 0.014 14.6 0.0 0.03 13.5 0.0 1.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_10 PF12846.2 KUM62808.1 - 0.021 14.2 0.0 0.2 11.0 0.0 1.9 1 1 1 2 2 2 0 AAA-like domain DUF2075 PF09848.4 KUM62808.1 - 0.036 13.0 0.1 0.043 12.7 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Cytidylate_kin2 PF13189.1 KUM62808.1 - 0.043 13.7 0.0 0.062 13.2 0.0 1.6 1 1 0 1 1 1 0 Cytidylate kinase-like family AAA_3 PF07726.6 KUM62808.1 - 0.053 13.1 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KUM62808.1 - 0.062 12.7 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 KUM62808.1 - 0.092 12.2 0.2 0.17 11.3 0.0 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_19 PF13245.1 KUM62808.1 - 0.16 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Peptidase_C78 PF07910.8 KUM62809.1 - 3.5e-72 242.0 0.0 4.7e-72 241.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.7 KUM62809.1 - 0.014 15.5 4.0 1.6 8.9 0.5 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 KUM62809.1 - 0.11 12.9 2.9 8.9 6.9 0.8 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KUM62809.1 - 0.16 12.2 0.8 0.47 10.7 0.6 1.9 1 0 0 1 1 1 0 C2H2-type zinc-finger domain DUF4190 PF13828.1 KUM62810.1 - 2.3 7.7 11.1 7.1 6.2 1.9 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4190) zf-rbx1 PF12678.2 KUM62811.1 - 7.8e-36 122.0 13.5 9.8e-36 121.7 9.3 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KUM62811.1 - 1.6e-17 63.1 10.3 2e-17 62.7 7.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KUM62811.1 - 3.3e-07 30.0 12.7 2.1e-06 27.4 8.8 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KUM62811.1 - 0.0012 18.4 11.9 0.022 14.4 8.3 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KUM62811.1 - 0.0033 17.0 9.7 0.3 10.7 6.9 2.2 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KUM62811.1 - 0.045 13.7 13.1 0.048 13.6 5.9 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KUM62811.1 - 0.18 11.7 9.3 0.75 9.8 6.5 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 KUM62811.1 - 0.42 10.3 6.5 1.1 9.0 2.2 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-HC5HC2H PF13771.1 KUM62811.1 - 0.67 10.1 10.3 43 4.3 7.2 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KUM62811.1 - 0.7 9.9 9.7 1.6 8.7 6.7 1.7 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_5 PF14634.1 KUM62811.1 - 1.1 9.0 11.9 7.9 6.3 8.2 2.3 1 1 0 1 1 1 0 zinc-RING finger domain PNRC PF15365.1 KUM62812.1 - 3.5e-05 23.7 7.3 3.5e-05 23.7 5.1 4.5 4 1 0 4 4 4 1 Proline-rich nuclear receptor coactivator GHMP_kinases_N PF00288.21 KUM62813.1 - 1e-13 51.1 0.0 2.1e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KUM62813.1 - 1.5e-05 25.1 0.0 2.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal SPC12 PF06645.8 KUM62814.1 - 5.3e-28 96.6 0.0 6.5e-28 96.3 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) ZYG-11_interact PF05884.7 KUM62814.1 - 0.0039 16.3 0.0 0.0045 16.1 0.0 1.1 1 0 0 1 1 1 1 Interactor of ZYG-11 DUF998 PF06197.8 KUM62814.1 - 0.016 14.5 0.3 0.018 14.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Na_Ca_ex PF01699.19 KUM62814.1 - 0.028 14.0 0.2 0.036 13.6 0.1 1.1 1 0 0 1 1 1 0 Sodium/calcium exchanger protein MIP PF00230.15 KUM62814.1 - 0.092 12.1 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Major intrinsic protein SdpI PF13630.1 KUM62814.1 - 0.18 11.5 1.1 0.24 11.1 0.8 1.1 1 0 0 1 1 1 0 SdpI/YhfL protein family PDT PF00800.13 KUM62816.1 - 1e-67 227.2 0.0 1.4e-67 226.7 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 KUM62816.1 - 1.2e-05 24.7 0.0 2.9e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 ACT domain eRF1_2 PF03464.10 KUM62817.1 - 3.4e-45 153.6 0.0 6.2e-45 152.7 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KUM62817.1 - 5e-38 129.8 0.7 9.2e-38 128.9 0.5 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 KUM62817.1 - 3.6e-21 75.1 0.0 5.7e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.21 KUM62817.1 - 0.029 13.8 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Aa_trans PF01490.13 KUM62818.1 - 9.7e-67 225.2 30.1 1.1e-66 224.9 20.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein p450 PF00067.17 KUM62819.1 - 1.5e-37 129.1 0.0 1.9e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KUM62820.1 - 2.1e-08 33.1 0.0 2.4e-08 32.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 polyprenyl_synt PF00348.12 KUM62822.1 - 5.4e-55 186.0 0.0 6.7e-55 185.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF3321 PF11968.3 KUM62823.1 - 1.2e-94 316.0 0.0 1.4e-94 315.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 KUM62823.1 - 0.0054 16.4 0.0 0.01 15.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ribosomal_L23eN PF03939.8 KUM62824.1 - 1.1e-21 76.6 7.7 1.1e-21 76.6 5.4 2.1 3 0 0 3 3 3 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 KUM62824.1 - 1.2e-16 60.4 2.6 1.2e-16 60.4 1.8 1.8 2 0 0 2 2 2 1 Ribosomal protein L23 MaoC_dehydratas PF01575.14 KUM62825.1 - 0.004 16.5 0.0 0.0067 15.8 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain DER1 PF04511.10 KUM62826.1 - 2.4e-24 85.9 8.5 2.7e-24 85.7 5.9 1.0 1 0 0 1 1 1 1 Der1-like family DKCLD PF08068.7 KUM62827.1 - 1.2e-28 98.8 1.6 6.5e-28 96.4 0.0 2.9 3 0 0 3 3 3 1 DKCLD (NUC011) domain TruB_N PF01509.13 KUM62827.1 - 4.6e-23 82.0 1.3 3.5e-20 72.6 0.1 3.9 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 KUM62827.1 - 3.6e-21 74.6 1.2 6.9e-21 73.7 0.8 1.5 1 0 0 1 1 1 1 PUA domain TFIIF_alpha PF05793.7 KUM62827.1 - 0.31 9.3 21.6 0.42 8.9 15.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RR_TM4-6 PF06459.7 KUM62827.1 - 3.5 7.4 14.2 4.9 6.9 9.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.6 KUM62827.1 - 4.9 6.7 25.7 7.8 6.1 17.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF4407 PF14362.1 KUM62827.1 - 9 5.1 6.4 14 4.5 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3331 PF11811.3 KUM62828.1 - 0.13 11.8 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3331) DUF4123 PF13503.1 KUM62829.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) DUF2093 PF09866.4 KUM62829.1 - 0.12 11.6 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) SMI1_KNR4 PF09346.5 KUM62830.1 - 2.2e-35 121.5 0.0 3.7e-35 120.7 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) UAA PF08449.6 KUM62832.1 - 6.7e-11 41.6 18.5 8.4e-11 41.3 12.8 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KUM62832.1 - 9.8e-10 38.2 6.7 9.8e-10 38.2 4.6 3.0 1 1 2 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 KUM62832.1 - 0.0011 19.0 4.7 0.0011 19.0 3.2 2.4 2 0 0 2 2 2 1 EamA-like transporter family Thioredoxin PF00085.15 KUM62833.1 - 0.00014 21.5 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin CLTH PF10607.4 KUM62834.1 - 9.2e-36 122.6 2.4 1.9e-35 121.7 1.7 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain YhdB PF14148.1 KUM62834.1 - 0.066 12.9 0.3 1.8 8.4 0.0 2.7 3 0 0 3 3 3 0 YhdB-like protein LisH PF08513.6 KUM62834.1 - 0.069 12.9 0.0 0.22 11.3 0.0 2.0 1 0 0 1 1 1 0 LisH DUF393 PF04134.7 KUM62834.1 - 0.14 13.2 2.9 43 5.2 0.1 3.6 3 1 0 3 3 3 0 Protein of unknown function, DUF393 UL73_N PF12522.3 KUM62834.1 - 0.16 11.5 7.7 0.34 10.4 5.4 1.5 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal Rad50_zn_hook PF04423.9 KUM62834.1 - 3.5 7.1 6.7 0.84 9.1 0.1 3.2 3 1 1 4 4 4 0 Rad50 zinc hook motif DUF2431 PF10354.4 KUM62835.1 - 2.3e-43 148.0 0.0 9e-28 97.3 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF2431) Myosin_head PF00063.16 KUM62836.1 - 2.4e-249 829.0 1.2 4e-249 828.3 0.8 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.14 KUM62836.1 - 3e-34 117.0 2.9 3e-34 117.0 2.0 2.3 2 0 0 2 2 2 1 DIL domain IQ PF00612.22 KUM62836.1 - 2.7e-14 51.3 30.1 0.00048 19.5 0.3 6.7 6 0 0 6 6 6 5 IQ calmodulin-binding motif AAA_22 PF13401.1 KUM62836.1 - 0.00022 21.3 0.1 0.0014 18.8 0.1 2.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KUM62836.1 - 0.00064 18.9 0.0 0.0019 17.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GAS PF13851.1 KUM62836.1 - 0.0011 18.2 25.8 0.019 14.1 9.0 2.8 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding TMP_2 PF06791.8 KUM62836.1 - 0.0016 18.0 1.4 0.0038 16.8 1.0 1.6 1 0 0 1 1 1 1 Prophage tail length tape measure protein Myosin_N PF02736.14 KUM62836.1 - 0.0022 17.6 0.6 0.0053 16.4 0.4 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 KUM62836.1 - 0.013 15.2 0.0 0.051 13.3 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 KUM62836.1 - 0.042 13.8 4.8 0.058 13.3 0.0 2.9 2 1 1 3 3 3 0 AAA ATPase domain Baculo_PEP_C PF04513.7 KUM62836.1 - 0.048 13.4 7.4 0.072 12.9 3.2 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC_tran PF00005.22 KUM62836.1 - 1.3 9.3 4.4 1.3 9.3 0.0 2.8 2 1 0 2 2 2 0 ABC transporter Exonuc_VII_L PF02601.10 KUM62836.1 - 1.3 8.1 14.4 2.8 7.0 10.0 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit FUSC PF04632.7 KUM62836.1 - 1.9 6.8 5.9 3.5 5.9 4.1 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tropomyosin_1 PF12718.2 KUM62836.1 - 4 7.2 27.7 14 5.4 4.4 3.0 1 1 1 2 2 2 0 Tropomyosin like APG6 PF04111.7 KUM62836.1 - 6 5.8 26.3 1 8.3 12.7 2.6 1 1 1 2 2 2 0 Autophagy protein Apg6 Ham1p_like PF01725.11 KUM62837.1 - 3.3e-55 186.3 0.0 3.8e-55 186.2 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Pkinase PF00069.20 KUM62838.1 - 1.7e-09 37.1 1.1 3.4e-08 32.9 0.1 3.0 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM62838.1 - 0.00018 20.6 0.1 0.0015 17.6 0.0 2.3 3 0 0 3 3 3 1 Protein tyrosine kinase Bestrophin PF01062.16 KUM62839.1 - 1.6e-38 132.3 0.0 3.9e-38 131.0 0.0 1.5 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF2510 PF10708.4 KUM62839.1 - 0.31 10.5 2.3 7.6 6.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2510) Arm PF00514.18 KUM62840.1 - 5.8e-70 228.9 28.5 5e-13 48.3 0.1 11.3 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KUM62840.1 - 1.1e-24 86.4 11.6 2.2e-06 27.8 0.2 7.3 3 2 2 6 6 6 5 HEAT repeats HEAT PF02985.17 KUM62840.1 - 1.9e-21 74.1 13.2 0.016 15.2 0.0 9.6 10 0 0 10 10 9 5 HEAT repeat HEAT_EZ PF13513.1 KUM62840.1 - 2.9e-16 59.4 8.3 0.017 15.6 0.0 8.4 6 1 3 9 9 8 5 HEAT-like repeat Adaptin_N PF01602.15 KUM62840.1 - 1.3e-12 46.8 6.4 6.2e-07 28.1 0.5 2.9 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.8 KUM62840.1 - 6e-12 45.2 6.9 0.001 18.2 0.1 3.4 2 1 1 3 3 3 3 Armadillo-like KAP PF05804.7 KUM62840.1 - 1.9e-10 39.3 0.5 3.5e-10 38.4 0.4 1.4 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 KUM62840.1 - 6.2e-10 38.6 0.4 7.9e-05 21.9 0.3 3.5 2 1 1 3 3 3 2 V-ATPase subunit H V-ATPase_H_C PF11698.3 KUM62840.1 - 0.0014 18.4 1.5 5.6 6.9 0.0 4.6 2 1 3 5 5 5 1 V-ATPase subunit H Vac14_Fab1_bd PF12755.2 KUM62840.1 - 0.005 17.1 0.1 2.3 8.6 0.0 3.7 1 1 2 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.11 KUM62840.1 - 0.018 15.4 5.7 22 5.8 0.2 6.1 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.4 KUM62840.1 - 1.9 8.2 4.8 11 5.8 0.2 3.8 4 1 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain GTP_EFTU PF00009.22 KUM62841.1 - 1.2e-53 181.4 0.0 1.9e-53 180.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KUM62841.1 - 2.5e-15 56.1 0.0 6e-15 54.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KUM62841.1 - 1.1e-07 31.8 0.0 8e-07 29.0 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KUM62841.1 - 3.6e-07 29.9 0.0 8.3e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 KUM62841.1 - 0.00017 21.1 0.0 0.0033 16.9 0.0 2.6 1 1 0 1 1 1 1 Elongation factor G, domain IV zf-U1 PF06220.7 KUM62841.1 - 0.28 10.7 0.1 0.59 9.7 0.1 1.4 1 0 0 1 1 1 0 U1 zinc finger Atg14 PF10186.4 KUM62843.1 - 1.9e-22 79.5 2.6 2.9e-22 78.9 1.8 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 KUM62843.1 - 1e-08 34.6 0.2 2.2e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 Autophagy protein Apg6 Mhr1 PF12829.2 KUM62844.1 - 1.1e-31 108.5 0.4 1.1e-31 108.5 0.3 1.8 2 0 0 2 2 2 1 Transcriptional regulation of mitochondrial recombination PP2C PF00481.16 KUM62845.1 - 5.1e-63 212.8 0.2 2.2e-50 171.4 0.1 3.1 1 1 1 2 2 2 2 Protein phosphatase 2C DUF4604 PF15377.1 KUM62846.1 - 2.1e-20 73.5 16.7 2.4e-20 73.3 11.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) F-box PF00646.28 KUM62847.1 - 0.0043 16.6 0.2 0.011 15.3 0.2 1.7 1 0 0 1 1 1 1 F-box domain DUF1059 PF06348.6 KUM62848.1 - 0.12 12.2 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1059) Alb1 PF09135.6 KUM62849.1 - 3.6e-30 104.8 13.8 5.3e-30 104.2 9.6 1.2 1 0 0 1 1 1 1 Alb1 Dynamin_N PF00350.18 KUM62849.1 - 0.2 11.4 1.9 0.35 10.6 1.3 1.5 1 1 0 1 1 1 0 Dynamin family Nop25 PF09805.4 KUM62849.1 - 0.64 10.0 8.9 1.2 9.2 6.2 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) SLX9 PF15341.1 KUM62849.1 - 5.5 7.4 12.6 7.3 7.0 8.8 1.4 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 UCH PF00443.24 KUM62850.1 - 9e-35 120.0 0.0 1.3e-34 119.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KUM62850.1 - 2.4e-08 33.7 0.1 9.4e-08 31.8 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-RING_2 PF13639.1 KUM62853.1 - 0.00094 18.9 1.6 0.0018 18.0 1.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KUM62853.1 - 0.0012 18.8 4.9 0.0026 17.7 3.4 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 KUM62853.1 - 0.0034 17.2 3.9 0.006 16.4 2.7 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-C3HC4 PF00097.20 KUM62853.1 - 0.0041 16.7 1.6 0.0092 15.6 1.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KUM62853.1 - 0.0051 16.5 5.8 0.0086 15.7 4.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KUM62853.1 - 0.014 15.0 3.8 0.029 14.0 2.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-dskA_traR PF01258.12 KUM62853.1 - 0.033 13.9 0.4 0.12 12.1 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger FHA PF00498.21 KUM62854.1 - 5.4e-14 52.0 0.0 1e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 KUM62854.1 - 1.6e-06 27.7 9.1 3e-06 26.9 6.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KUM62854.1 - 0.0012 18.8 5.9 0.0024 17.9 4.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KUM62854.1 - 0.003 17.2 6.1 0.0057 16.3 4.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KUM62854.1 - 0.019 14.6 7.4 0.043 13.4 5.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KUM62854.1 - 0.021 14.8 9.3 0.04 13.9 6.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KUM62854.1 - 0.038 13.8 2.8 0.079 12.8 1.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.6 KUM62854.1 - 0.25 11.3 5.6 0.61 10.1 3.9 1.7 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.1 KUM62854.1 - 0.65 9.9 7.0 1.4 8.8 4.5 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF3722 PF12519.3 KUM62855.1 - 5.6e-50 169.9 0.7 8.7e-50 169.3 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Ribosomal_L10 PF00466.15 KUM62856.1 - 3.6e-18 65.3 0.0 7.2e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Ribonuc_L-PSP PF01042.16 KUM62856.1 - 0.098 12.4 0.0 0.35 10.6 0.0 1.9 2 0 0 2 2 2 0 Endoribonuclease L-PSP U1snRNP70_N PF12220.3 KUM62857.1 - 1.3e-31 108.7 1.1 1.3e-31 108.7 0.8 1.6 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 KUM62857.1 - 9.9e-16 57.1 0.0 1.6e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM62857.1 - 1.6e-11 43.9 0.0 2.6e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM62857.1 - 5.8e-07 29.2 0.0 1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) L51_S25_CI-B8 PF05047.11 KUM62858.1 - 1.4e-14 53.5 0.1 2e-14 53.0 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Solute_trans_a PF03619.11 KUM62859.1 - 1.8e-43 148.8 14.4 2.2e-43 148.5 10.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Fic PF02661.13 KUM62860.1 - 0.00035 21.2 0.1 0.0015 19.2 0.0 2.0 2 0 0 2 2 2 1 Fic/DOC family Dynamin_N PF00350.18 KUM62861.1 - 1.4e-16 60.7 0.1 3.4e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KUM62861.1 - 8.5e-10 38.6 0.1 6.3e-09 35.8 0.0 2.5 3 1 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KUM62861.1 - 5e-07 29.3 0.3 4.9e-06 26.0 0.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 KUM62861.1 - 0.003 18.0 0.7 0.58 10.6 0.2 3.8 2 1 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 KUM62861.1 - 0.038 13.5 0.0 0.089 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.8 KUM62861.1 - 0.039 12.7 0.0 0.082 11.7 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_18 PF13238.1 KUM62861.1 - 0.046 14.0 0.1 0.21 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 KUM62861.1 - 0.059 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_17 PF13207.1 KUM62861.1 - 0.096 13.5 0.1 0.77 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain PTCB-BRCT PF12738.2 KUM62862.1 - 2e-51 171.6 0.5 8.9e-23 79.9 0.1 4.3 4 0 0 4 4 4 4 twin BRCT domain BRCT PF00533.21 KUM62862.1 - 1.3e-29 102.1 0.7 4.7e-14 52.2 0.1 4.5 4 1 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain Pkinase PF00069.20 KUM62863.1 - 3e-72 242.9 0.0 3.4e-72 242.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM62863.1 - 2.1e-34 118.7 0.0 2.6e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM62863.1 - 0.006 15.5 0.0 0.01 14.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KUM62863.1 - 0.014 15.1 0.1 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KUM62863.1 - 0.031 13.3 0.1 0.067 12.2 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Snf7 PF03357.16 KUM62864.1 - 4.2e-35 120.6 20.9 5.3e-35 120.3 13.2 1.7 1 1 1 2 2 2 1 Snf7 V_ATPase_I PF01496.14 KUM62864.1 - 0.025 12.4 2.3 0.029 12.2 1.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ist1 PF03398.9 KUM62864.1 - 0.032 13.6 4.1 0.043 13.2 2.9 1.3 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway YlqD PF11068.3 KUM62864.1 - 6.7 6.7 17.1 5.6 7.0 7.1 2.2 1 1 1 2 2 2 0 YlqD protein Pro_isomerase PF00160.16 KUM62866.1 - 1.6e-38 132.3 0.0 2.9e-38 131.4 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 KUM62866.1 - 2.3e-06 27.0 1.3 5e-06 25.8 0.0 2.2 2 1 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.10 KUM62866.1 - 0.00058 19.7 0.1 0.0043 16.9 0.0 2.4 1 1 1 2 2 2 1 U-box domain PIF1 PF05970.9 KUM62867.1 - 2e-65 221.1 0.0 4.3e-51 173.9 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 KUM62867.1 - 2.5e-18 66.3 0.0 4.5e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KUM62867.1 - 9.2e-07 29.0 0.0 2e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KUM62867.1 - 7.8e-06 25.5 0.2 1.6e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 KUM62867.1 - 4e-05 23.7 0.3 0.00065 19.8 0.1 2.9 2 1 0 2 2 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 KUM62867.1 - 4.5e-05 21.4 0.1 0.00027 18.8 0.0 2.1 3 0 0 3 3 3 1 Helicase RNA_helicase PF00910.17 KUM62867.1 - 5.4e-05 23.3 0.1 0.027 14.6 0.0 2.8 2 1 0 2 2 2 1 RNA helicase AAA_16 PF13191.1 KUM62867.1 - 0.00084 19.3 0.6 0.003 17.5 0.0 2.2 3 0 0 3 3 2 1 AAA ATPase domain DUF2075 PF09848.4 KUM62867.1 - 0.0068 15.4 0.0 0.02 13.8 0.0 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 KUM62867.1 - 0.0084 15.4 1.9 0.01 15.1 0.0 2.0 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain AAA PF00004.24 KUM62867.1 - 0.011 15.9 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KUM62867.1 - 0.014 14.6 0.0 0.053 12.7 0.0 2.0 1 1 1 2 2 2 0 PhoH-like protein T2SE PF00437.15 KUM62867.1 - 0.019 13.8 0.0 0.04 12.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.1 KUM62867.1 - 0.02 14.3 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 KUM62867.1 - 0.026 13.1 0.0 0.046 12.3 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.2 KUM62867.1 - 0.041 13.3 0.2 0.78 9.1 0.1 2.3 2 1 0 2 2 2 0 AAA-like domain AAA_14 PF13173.1 KUM62867.1 - 0.066 13.1 0.0 0.23 11.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.2 KUM62867.1 - 0.077 12.0 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 AAA_5 PF07728.9 KUM62867.1 - 0.088 12.5 0.0 5.4 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 KUM62867.1 - 0.089 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 KUM62867.1 - 0.1 12.8 0.3 0.59 10.4 0.1 2.6 3 1 0 3 3 2 0 ABC transporter Helicase_RecD PF05127.9 KUM62867.1 - 0.1 12.2 0.1 0.45 10.1 0.1 2.0 1 1 0 1 1 1 0 Helicase AAA_11 PF13086.1 KUM62867.1 - 0.13 11.7 3.7 0.23 10.9 0.0 2.9 3 1 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 KUM62867.1 - 0.69 9.5 3.6 0.61 9.7 0.2 2.4 1 1 1 2 2 2 0 Archaeal ATPase YjeF_N PF03853.10 KUM62868.1 - 6.9e-41 139.6 0.1 1e-40 139.1 0.1 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 KUM62868.1 - 2e-10 41.1 0.7 2e-10 41.1 0.5 2.1 2 0 0 2 2 2 1 FDF domain NTP_transferase PF00483.18 KUM62868.1 - 0.029 13.6 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase TIM PF00121.13 KUM62869.1 - 1.9e-91 305.4 1.2 2.3e-91 305.2 0.8 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.9 KUM62869.1 - 0.018 14.2 0.1 0.028 13.6 0.1 1.3 1 0 0 1 1 1 0 CutC family DeoRC PF00455.17 KUM62869.1 - 0.019 14.6 0.4 5.6 6.5 0.0 2.6 2 1 1 3 3 3 0 DeoR C terminal sensor domain NUC129 PF08157.6 KUM62870.1 - 0.29 11.0 2.4 0.57 10.1 0.7 2.2 2 0 0 2 2 2 0 NUC129 domain BNIP2 PF12496.3 KUM62870.1 - 0.92 9.6 11.7 0.14 12.3 5.2 1.7 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 NmrA PF05368.8 KUM62871.1 - 3.3e-13 49.4 0.0 4.7e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KUM62871.1 - 1e-06 28.8 0.0 1.4e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding EXOSC1 PF10447.4 KUM62872.1 - 2.1e-28 98.0 0.9 3.3e-28 97.4 0.7 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 KUM62872.1 - 3.1e-14 51.9 0.2 5.1e-14 51.2 0.1 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region CRISPR_Cse2 PF09485.5 KUM62872.1 - 0.032 14.2 0.0 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Prp19 PF08606.6 KUM62873.1 - 7.4e-32 108.9 1.0 1.2e-31 108.2 0.7 1.3 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 KUM62873.1 - 1.6e-18 65.7 2.3 7.9e-06 25.5 0.0 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KUM62873.1 - 6e-08 31.9 0.5 0.0033 16.2 0.0 2.2 1 1 1 2 2 2 2 Coatomer WD associated region eIF2A PF08662.6 KUM62873.1 - 2.3e-05 24.1 0.1 0.026 14.2 0.0 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A U-box PF04564.10 KUM62873.1 - 0.0035 17.2 0.0 0.0068 16.3 0.0 1.4 1 0 0 1 1 1 1 U-box domain DUF3312 PF11768.3 KUM62873.1 - 0.0044 15.3 0.1 0.13 10.4 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3312) Cytochrom_D1 PF02239.11 KUM62873.1 - 0.048 11.9 0.9 0.51 8.5 0.1 2.4 1 1 3 4 4 4 0 Cytochrome D1 heme domain zf-Nse PF11789.3 KUM62873.1 - 0.049 13.1 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit EH_Signature PF15611.1 KUM62873.1 - 0.14 11.1 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 EH_Signature domain HPS3_N PF14761.1 KUM62873.1 - 0.16 11.3 0.1 0.75 9.1 0.0 2.2 2 1 1 3 3 3 0 Hermansky-Pudlak syndrome 3 Vps16_N PF04841.8 KUM62874.1 - 1.3e-98 330.2 0.0 1.7e-98 329.8 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 KUM62874.1 - 8.6e-81 271.3 0.0 1.5e-80 270.5 0.0 1.4 1 0 0 1 1 1 1 Vps16, C-terminal region PBP PF01161.15 KUM62877.1 - 5.9e-13 48.8 0.0 9.6e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Sld5 PF05916.6 KUM62877.1 - 0.04 14.1 0.1 0.091 13.0 0.1 1.7 1 0 0 1 1 1 0 GINS complex protein Peptidase_S26 PF10502.4 KUM62878.1 - 1.3e-06 27.9 0.0 0.00037 20.0 0.0 2.3 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 KUM62878.1 - 7.8e-05 22.2 0.1 0.00017 21.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like Sulfatase PF00884.18 KUM62879.1 - 7.5e-69 232.2 0.0 9.7e-69 231.8 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Fungal_trans_2 PF11951.3 KUM62880.1 - 6.6e-12 44.7 0.1 1.1e-11 44.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM62880.1 - 5.5e-10 38.9 8.0 1e-09 38.1 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MGC-24 PF05283.6 KUM62880.1 - 0.0096 15.7 2.2 0.02 14.7 1.5 1.4 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24) ECH_C PF13766.1 KUM62881.1 - 2.1e-39 134.2 0.4 5e-39 133.1 0.3 1.6 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 KUM62881.1 - 2.5e-26 92.3 0.0 1.6e-25 89.6 0.0 1.9 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family Ribosomal_L4 PF00573.17 KUM62882.1 - 2.8e-43 147.5 0.0 3.9e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Peptidase_C48 PF02902.14 KUM62885.1 - 4.6e-13 49.2 0.0 2.9e-12 46.7 0.0 1.9 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF4131 PF13567.1 KUM62886.1 - 0.012 14.9 0.2 1.2 8.5 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Cullin PF00888.17 KUM62887.1 - 6.9e-122 407.9 0.0 8.3e-122 407.6 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KUM62887.1 - 4.1e-25 87.3 0.7 1.3e-24 85.7 0.5 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain HbrB PF08539.6 KUM62887.1 - 0.00048 20.0 0.0 0.0016 18.2 0.0 1.9 1 1 0 1 1 1 1 HbrB-like HTH_34 PF13601.1 KUM62887.1 - 0.044 13.8 0.0 1 9.4 0.0 2.5 2 0 0 2 2 2 0 Winged helix DNA-binding domain APH PF01636.18 KUM62888.1 - 3e-17 63.1 0.1 5.8e-17 62.2 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KUM62888.1 - 0.00089 18.3 0.0 0.062 12.3 0.0 2.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KUM62888.1 - 0.011 15.0 0.0 1.3 8.3 0.0 2.5 2 0 0 2 2 2 0 RIO1 family Med9 PF07544.8 KUM62888.1 - 0.15 11.7 1.9 12 5.7 0.2 2.7 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 ADH_N PF08240.7 KUM62889.1 - 2.2e-27 94.9 0.2 4.2e-27 94.0 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM62889.1 - 6e-09 35.5 0.4 1.2e-08 34.5 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KUM62889.1 - 6.6e-06 25.6 0.2 1.3e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated HI0933_like PF03486.9 KUM62889.1 - 0.0025 16.3 0.4 0.0081 14.6 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 KUM62889.1 - 0.021 13.7 0.1 0.035 13.0 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.15 KUM62889.1 - 0.032 14.3 0.1 0.077 13.0 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 KUM62889.1 - 0.038 14.0 0.4 0.071 13.1 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 KUM62889.1 - 0.047 13.0 0.1 0.081 12.2 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_2 PF00890.19 KUM62889.1 - 0.057 12.2 1.5 0.11 11.2 0.5 1.7 1 1 1 2 2 2 0 FAD binding domain NAD_binding_10 PF13460.1 KUM62889.1 - 0.08 12.9 0.2 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 NADH(P)-binding F420_oxidored PF03807.12 KUM62889.1 - 0.093 13.1 0.2 0.19 12.2 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Methyltransf_18 PF12847.2 KUM62889.1 - 0.12 12.9 0.4 0.39 11.3 0.1 2.0 2 1 0 2 2 1 0 Methyltransferase domain Pyr_redox PF00070.22 KUM62889.1 - 0.13 12.7 0.2 1.4 9.4 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ank_2 PF12796.2 KUM62891.1 - 8.4e-13 48.4 0.0 4.8e-12 46.0 0.0 1.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KUM62891.1 - 8.5e-13 47.4 0.0 1.1e-06 28.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 KUM62891.1 - 1.9e-08 33.7 0.0 6.9e-05 22.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 KUM62891.1 - 2.6e-08 33.8 0.0 7.1e-08 32.4 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 KUM62891.1 - 3.2e-07 30.6 0.1 0.00066 20.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) F-box-like PF12937.2 KUM62891.1 - 1.1e-05 25.0 0.4 1.9e-05 24.2 0.2 1.4 1 0 0 1 1 1 1 F-box-like Tet_JBP PF12851.2 KUM62891.1 - 0.058 12.6 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily Cu-oxidase_3 PF07732.10 KUM62892.1 - 1.8e-35 121.2 5.3 4.1e-35 120.0 3.6 1.6 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.17 KUM62892.1 - 5.6e-33 114.0 1.0 9.5e-33 113.3 0.2 1.7 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KUM62892.1 - 0.38 10.2 2.9 0.97 8.9 1.2 2.2 2 1 0 2 2 2 0 Multicopper oxidase DUF3433 PF11915.3 KUM62893.1 - 6e-36 122.4 12.2 9.8e-22 76.9 2.7 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) AP_endonuc_2 PF01261.19 KUM62894.1 - 4.5e-06 26.1 0.0 1.6e-05 24.3 0.0 1.9 1 1 1 2 2 2 1 Xylose isomerase-like TIM barrel DUF1264 PF06884.6 KUM62895.1 - 1.6e-76 255.4 0.0 2.1e-76 255.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) TPP_enzyme_N PF02776.13 KUM62896.1 - 1.4e-33 115.8 0.1 2.4e-33 115.0 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KUM62896.1 - 3.1e-14 52.8 0.0 9.9e-14 51.1 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KUM62896.1 - 6.6e-14 51.8 0.0 1.3e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain MNHE PF01899.11 KUM62897.1 - 0.082 12.5 0.0 0.28 10.8 0.0 1.7 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit adh_short PF00106.20 KUM62898.1 - 0.00027 20.8 0.1 0.0035 17.2 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase NAD_kinase PF01513.16 KUM62899.1 - 6.3e-68 228.6 0.0 9.1e-68 228.1 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase L_biotic_typeA PF04604.8 KUM62899.1 - 0.072 12.7 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Type-A lantibiotic Lactamase_B PF00753.22 KUM62900.1 - 2.1e-33 115.6 0.4 2.7e-33 115.2 0.3 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KUM62900.1 - 1.4e-06 28.0 0.0 2.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KUM62900.1 - 0.001 18.8 0.1 0.0022 17.7 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.15 KUM62900.1 - 0.0026 17.1 0.1 0.007 15.6 0.0 1.6 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family ADH_N PF08240.7 KUM62900.1 - 0.057 13.1 0.1 0.096 12.4 0.1 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Las1 PF04031.8 KUM62901.1 - 8.1e-45 152.2 0.0 1.4e-44 151.5 0.0 1.3 1 0 0 1 1 1 1 Las1-like GATA PF00320.22 KUM62903.1 - 0.00014 21.1 3.5 0.0031 16.8 0.7 2.5 2 0 0 2 2 2 2 GATA zinc finger Rep_fac-A_3 PF08661.6 KUM62904.1 - 2.6e-25 88.4 0.0 3.1e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Prp19_bind PF06991.6 KUM62905.1 - 4.7e-47 160.5 33.3 4.7e-47 160.5 23.0 2.5 2 1 0 2 2 2 1 Splicing factor, Prp19-binding domain TRAPP PF04051.11 KUM62906.1 - 1.4e-36 125.3 0.0 1.8e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Dak1 PF02733.12 KUM62907.1 - 6.8e-109 363.3 0.2 1e-108 362.8 0.1 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 KUM62907.1 - 6.5e-43 146.4 0.8 6.5e-43 146.4 0.6 1.7 2 0 0 2 2 2 1 DAK2 domain Pox_P4B PF03292.9 KUM62907.1 - 0.21 9.4 0.0 0.31 8.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus P4B major core protein LSM PF01423.17 KUM62908.1 - 4.7e-19 67.6 0.2 6.5e-19 67.2 0.1 1.2 1 0 0 1 1 1 1 LSM domain Lyase_1 PF00206.15 KUM62908.1 - 0.13 11.4 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Lyase Fructosamin_kin PF03881.9 KUM62909.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase FPN1 PF06963.7 KUM62910.1 - 4.5e-148 493.2 23.4 5.2e-148 493.0 16.2 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Fungal_trans PF04082.13 KUM62912.1 - 4.7e-24 84.6 0.0 7.8e-24 83.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM62912.1 - 2.4e-09 36.9 11.9 3.9e-09 36.2 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain hDGE_amylase PF14701.1 KUM62912.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme ERG4_ERG24 PF01222.12 KUM62913.1 - 4.3e-156 519.7 4.9 5.1e-156 519.5 3.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KUM62913.1 - 2.1e-05 23.9 0.1 5.4e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Man-6-P_recep PF02157.10 KUM62914.1 - 3.7e-12 45.8 0.1 5e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.13 KUM62914.1 - 3.3e-09 36.6 0.1 0.0005 19.8 0.0 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.5 KUM62914.1 - 4.9e-05 22.7 0.1 0.00011 21.5 0.0 1.7 1 1 0 1 1 1 1 Autophagy-related protein 27 Glyco_hydro_3 PF00933.16 KUM62915.1 - 3.7e-94 315.0 0.0 5.7e-94 314.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KUM62915.1 - 3.9e-56 190.1 0.7 2.3e-55 187.5 0.5 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KUM62915.1 - 6.5e-17 61.2 0.2 1.3e-16 60.3 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain ADH_zinc_N_2 PF13602.1 KUM62916.1 - 3.2e-15 57.1 0.4 7e-15 56.0 0.3 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KUM62916.1 - 1.1e-11 44.4 0.9 2e-11 43.5 0.6 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KUM62916.1 - 3e-05 24.1 0.5 4.4e-05 23.5 0.4 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KUM62916.1 - 0.00081 19.3 0.7 0.0013 18.6 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.3 KUM62916.1 - 0.0022 17.7 0.7 0.0047 16.6 0.5 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_N PF08240.7 KUM62916.1 - 0.015 15.0 0.0 0.053 13.2 0.0 1.9 2 1 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 KUM62916.1 - 0.025 14.1 0.8 0.067 12.7 0.2 1.8 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Semialdhyde_dh PF01118.19 KUM62916.1 - 0.026 14.8 0.3 0.043 14.1 0.2 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KUM62916.1 - 0.029 14.2 0.6 0.048 13.5 0.4 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.12 KUM62916.1 - 0.04 12.8 0.3 0.12 11.2 0.1 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain EBP PF05241.7 KUM62917.1 - 3.4e-09 36.0 6.4 4.1e-09 35.7 0.9 2.2 2 1 0 2 2 2 2 Emopamil binding protein bZIP_1 PF00170.16 KUM62918.1 - 0.00079 19.3 12.2 0.0013 18.6 7.2 2.1 1 1 1 2 2 2 1 bZIP transcription factor EcoR124_C PF12008.3 KUM62918.1 - 0.0075 15.4 1.0 0.0075 15.4 0.7 1.4 2 0 0 2 2 2 1 Type I restriction and modification enzyme - subunit R C terminal Dynactin PF12455.3 KUM62918.1 - 0.047 12.6 3.7 0.079 11.8 2.6 1.3 1 0 0 1 1 1 0 Dynein associated protein A_deamin PF02137.13 KUM62919.1 - 6.1e-44 150.7 0.0 1.3e-43 149.7 0.0 1.5 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain GCV_T PF01571.16 KUM62920.1 - 0.026 13.9 0.0 0.097 12.0 0.0 1.9 2 1 1 3 3 3 0 Aminomethyltransferase folate-binding domain Dioxygenase_N PF04444.9 KUM62920.1 - 0.12 12.3 0.1 0.28 11.2 0.1 1.6 1 0 0 1 1 1 0 Catechol dioxygenase N terminus HEAT PF02985.17 KUM62921.1 - 1.1e-43 143.3 14.8 0.0028 17.5 0.1 13.2 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.1 KUM62921.1 - 8.6e-35 118.8 0.6 6.6e-09 35.9 0.0 7.4 2 2 6 8 8 8 7 HEAT repeats Vac14_Fab1_bd PF12755.2 KUM62921.1 - 1.1e-11 45.0 3.5 0.0009 19.5 0.0 7.2 5 2 4 9 9 9 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KUM62921.1 - 2.8e-10 40.3 10.5 0.016 15.6 0.0 8.9 6 3 4 10 10 10 2 HEAT-like repeat Adaptin_N PF01602.15 KUM62921.1 - 2.4e-07 29.4 10.6 1.1e-05 23.9 2.0 4.0 3 1 1 4 4 4 3 Adaptin N terminal region CLASP_N PF12348.3 KUM62921.1 - 0.0012 18.2 2.4 0.3 10.3 0.1 4.4 3 2 2 5 5 5 1 CLASP N terminal DUF2435 PF10363.4 KUM62921.1 - 0.0013 18.6 5.3 0.78 9.6 0.2 4.4 3 1 1 4 4 4 1 Protein of unknown function (DUF2435) Cnd1 PF12717.2 KUM62921.1 - 0.016 15.0 5.8 0.93 9.3 0.4 4.3 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 KUM62921.1 - 0.035 13.9 10.9 1.6 8.7 0.0 6.4 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat Sp38 PF07354.7 KUM62921.1 - 0.036 12.7 0.0 0.9 8.1 0.0 2.2 2 0 0 2 2 2 0 Zona-pellucida-binding protein (Sp38) Proteasom_PSMB PF10508.4 KUM62921.1 - 0.38 8.9 5.2 0.72 8.0 0.1 2.9 2 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit Glyco_transf_90 PF05686.7 KUM62923.1 - 1.9e-19 69.6 10.0 1.5e-16 60.1 5.1 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 90 Abhydrolase_6 PF12697.2 KUM62924.1 - 4.5e-22 79.0 0.5 1.3e-21 77.4 0.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM62924.1 - 1.2e-06 28.3 0.0 2.6e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM62924.1 - 0.00026 20.6 0.0 0.00044 19.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Arb2 PF09757.4 KUM62924.1 - 0.019 14.4 0.0 0.056 12.8 0.0 1.7 2 0 0 2 2 2 0 Arb2 domain Aldolase PF01081.14 KUM62924.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 KDPG and KHG aldolase Myotub-related PF06602.9 KUM62925.1 - 3.8e-123 410.7 0.0 5.7e-123 410.1 0.0 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Ribosomal_S3_C PF00189.15 KUM62925.1 - 6.3e-16 58.3 0.1 1.2e-15 57.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 KUM62925.1 - 2.3e-11 43.0 0.0 4.6e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 KH domain Y_phosphatase3 PF13350.1 KUM62925.1 - 0.11 12.7 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family FAD_binding_1 PF00667.15 KUM62926.1 - 2.8e-06 26.9 0.3 3.6e-06 26.5 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KUM62926.1 - 1.4e-05 25.6 0.0 2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain p450 PF00067.17 KUM62927.1 - 2.3e-31 108.8 0.0 2.5e-31 108.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FA_desaturase PF00487.19 KUM62928.1 - 1e-37 129.9 30.0 1.6e-37 129.3 20.8 1.3 1 0 0 1 1 1 1 Fatty acid desaturase GFA PF04828.9 KUM62929.1 - 3.4e-22 78.2 0.1 3.9e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Glyco_transf_8 PF01501.15 KUM62930.1 - 1.3e-31 109.7 0.0 2.4e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 KUM62930.1 - 0.00025 20.8 0.1 0.00043 20.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase SLS PF14611.1 KUM62931.1 - 1.8e-52 177.8 0.0 7.9e-52 175.7 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator Glyco_hydro_53 PF07745.8 KUM62931.1 - 0.047 12.4 0.0 0.076 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 GST_C PF00043.20 KUM62932.1 - 9.4e-15 54.3 0.0 1.4e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KUM62932.1 - 9.6e-14 51.3 0.0 1.6e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KUM62932.1 - 5.5e-13 48.8 0.0 1.1e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KUM62932.1 - 5.5e-10 39.1 0.0 1.2e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KUM62932.1 - 1.2e-07 32.1 0.2 1.8e-07 31.5 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KUM62932.1 - 5.3e-07 29.4 0.0 1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HCMV_UL139 PF12507.3 KUM62933.1 - 0.042 14.0 2.5 0.054 13.6 1.7 1.2 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein Nop25 PF09805.4 KUM62933.1 - 0.09 12.8 13.9 0.069 13.2 8.5 1.6 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) PRKCSH-like PF12999.2 KUM62933.1 - 0.093 12.3 1.2 0.12 11.9 0.8 1.1 1 0 0 1 1 1 0 Glucosidase II beta subunit-like PDEase_II PF02112.10 KUM62933.1 - 0.11 11.4 0.3 0.13 11.1 0.2 1.1 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Spc7 PF08317.6 KUM62933.1 - 0.16 10.5 9.1 0.2 10.2 6.3 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3552 PF12072.3 KUM62933.1 - 0.18 10.9 13.4 0.24 10.5 9.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Resolvase PF00239.16 KUM62933.1 - 0.29 11.0 3.9 0.36 10.6 2.7 1.1 1 0 0 1 1 1 0 Resolvase, N terminal domain Phage_GP20 PF06810.6 KUM62933.1 - 0.41 10.0 10.3 0.58 9.5 7.1 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF2951 PF11166.3 KUM62933.1 - 0.91 9.4 6.8 1.3 8.9 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) IncA PF04156.9 KUM62933.1 - 1.3 8.6 6.7 1.5 8.3 4.7 1.1 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 KUM62933.1 - 1.4 6.6 4.8 1.6 6.4 3.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ADIP PF11559.3 KUM62933.1 - 1.7 8.5 10.6 2.3 8.1 7.4 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Peptidase_S49_N PF08496.5 KUM62933.1 - 3.6 7.3 8.9 4.4 7.0 6.1 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TMPIT PF07851.8 KUM62933.1 - 4.7 6.1 6.4 5.8 5.8 4.4 1.0 1 0 0 1 1 1 0 TMPIT-like protein APG6 PF04111.7 KUM62933.1 - 5.3 5.9 10.2 6.8 5.6 7.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 BRE1 PF08647.6 KUM62933.1 - 5.8 6.9 14.9 9.4 6.2 10.4 1.3 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase NT-C2 PF10358.4 KUM62934.1 - 4.9e-30 103.8 0.0 7.3e-30 103.3 0.0 1.3 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins SF3b10 PF07189.6 KUM62937.1 - 1.1e-36 124.5 0.0 1.2e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DUF3074 PF11274.3 KUM62938.1 - 2.5e-61 206.5 1.3 6.1e-61 205.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) START PF01852.14 KUM62938.1 - 0.017 14.4 0.1 2.8 7.1 0.0 2.8 3 0 0 3 3 3 0 START domain DUF4618 PF15397.1 KUM62938.1 - 0.089 12.1 14.9 0.11 11.7 3.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DivIC PF04977.10 KUM62938.1 - 0.3 10.6 10.4 0.045 13.2 1.8 2.9 2 0 0 2 2 2 0 Septum formation initiator HALZ PF02183.13 KUM62938.1 - 0.34 10.6 9.3 0.064 12.9 2.0 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF342 PF03961.8 KUM62938.1 - 1 7.6 13.5 0.19 10.1 5.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) bZIP_1 PF00170.16 KUM62938.1 - 1.2 9.1 14.1 0.034 14.0 4.6 2.4 2 0 0 2 2 2 0 bZIP transcription factor DUF3450 PF11932.3 KUM62938.1 - 1.6 7.8 16.3 0.022 14.0 4.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) TSC22 PF01166.13 KUM62938.1 - 1.7 8.6 6.4 0.4 10.6 0.6 2.8 3 0 0 3 3 3 0 TSC-22/dip/bun family FlaC_arch PF05377.6 KUM62938.1 - 4.6 7.2 7.2 3.4 7.6 0.8 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF2730 PF10805.3 KUM62938.1 - 5 6.8 9.3 11 5.8 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) GST_C_2 PF13410.1 KUM62939.1 - 4.6e-09 36.0 0.0 9.7e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KUM62939.1 - 0.0052 17.2 0.0 0.0086 16.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KUM62939.1 - 0.02 14.8 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain CorA PF01544.13 KUM62939.1 - 0.025 13.6 0.0 3.2 6.7 0.0 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein ADH_zinc_N PF00107.21 KUM62940.1 - 3.4e-28 97.7 0.2 5.4e-28 97.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KUM62940.1 - 1e-15 58.7 0.0 2.3e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM62940.1 - 3.7e-10 39.5 0.0 1.2e-09 37.8 0.0 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 KUM62940.1 - 0.004 17.1 0.0 0.0079 16.1 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.16 KUM62940.1 - 0.0069 15.9 0.2 0.029 13.9 0.1 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain TyeA PF09059.5 KUM62941.1 - 0.09 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 TyeA F-box PF00646.28 KUM62942.1 - 0.0097 15.5 0.1 0.038 13.6 0.1 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KUM62942.1 - 0.01 15.5 0.1 0.025 14.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like ABC_tran PF00005.22 KUM62943.1 - 4.1e-17 62.7 0.0 8.9e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KUM62943.1 - 6e-05 23.1 0.1 0.27 11.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KUM62943.1 - 0.00031 20.7 0.0 0.00047 20.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 KUM62943.1 - 0.0022 16.9 0.2 0.0032 16.4 0.1 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 KUM62943.1 - 0.0032 17.6 0.4 0.064 13.3 0.1 2.6 1 1 1 2 2 2 1 AAA domain SMC_N PF02463.14 KUM62943.1 - 0.0084 15.3 0.2 0.71 9.0 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 KUM62943.1 - 0.011 15.1 0.4 0.078 12.3 0.1 2.0 2 0 0 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.13 KUM62943.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 KUM62943.1 - 0.074 13.2 0.0 0.46 10.6 0.0 2.2 2 1 0 2 2 2 0 RNA helicase NACHT PF05729.7 KUM62943.1 - 0.08 12.5 0.0 0.11 12.2 0.0 1.4 1 1 0 1 1 1 0 NACHT domain SbcCD_C PF13558.1 KUM62943.1 - 0.091 12.6 0.1 0.33 10.9 0.1 1.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KUM62943.1 - 0.11 12.0 0.4 0.23 11.0 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 KUM62943.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KUM62943.1 - 0.13 12.5 0.2 1.3 9.2 0.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KUM62943.1 - 0.14 12.0 0.0 2.6 7.9 0.0 2.6 2 1 1 3 3 3 0 AAA domain ATP_bind_1 PF03029.12 KUM62943.1 - 0.18 11.3 0.1 0.26 10.7 0.1 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ABC_membrane PF00664.18 KUM62944.1 - 7e-22 78.1 1.8 1.1e-21 77.5 1.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KUM62944.1 - 1.7e-15 57.5 0.0 2.9e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 KUM62944.1 - 0.0001 21.7 0.1 0.00023 20.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF87 PF01935.12 KUM62944.1 - 0.00066 19.5 0.2 0.0011 18.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF87 Miro PF08477.8 KUM62944.1 - 0.016 15.6 0.0 0.028 14.9 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein AAA_16 PF13191.1 KUM62944.1 - 0.017 15.1 0.1 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.1 KUM62944.1 - 0.021 14.8 0.1 0.037 13.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 KUM62944.1 - 0.022 13.7 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.18 KUM62944.1 - 0.037 13.9 0.1 0.071 13.0 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF258 PF03193.11 KUM62944.1 - 0.053 12.7 0.1 0.09 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 T2SE PF00437.15 KUM62944.1 - 0.065 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 KUM62944.1 - 0.075 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.13 KUM62944.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.1 KUM62944.1 - 0.11 12.8 0.2 0.18 12.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 KUM62944.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KUM62944.1 - 0.14 13.0 0.1 0.3 11.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain VirB3 PF05101.8 KUM62944.1 - 3.3 7.7 4.9 5.9 6.9 0.2 2.4 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein DUF1882 PF08966.6 KUM62945.1 - 0.092 12.7 0.2 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1882) DAO PF01266.19 KUM62947.1 - 1.1e-20 73.8 0.2 1.8e-20 73.1 0.1 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KUM62947.1 - 0.0017 18.7 1.2 0.0054 17.1 0.8 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KUM62947.1 - 0.015 15.2 0.2 0.048 13.5 0.2 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KUM62947.1 - 0.033 14.2 0.2 0.062 13.3 0.1 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KUM62947.1 - 0.05 12.6 0.7 0.14 11.1 0.0 1.9 2 0 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.13 KUM62947.1 - 0.06 12.9 0.8 0.12 12.0 0.6 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KUM62947.1 - 0.087 11.8 0.4 0.14 11.1 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 KUM62947.1 - 0.11 12.2 0.1 0.41 10.3 0.1 1.9 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.16 KUM62947.1 - 0.41 10.4 3.4 0.29 10.9 0.3 2.2 3 0 0 3 3 3 0 ThiF family BNR_2 PF13088.1 KUM62949.1 - 7e-05 22.2 0.0 0.0024 17.2 0.0 2.0 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 KUM62949.1 - 0.00088 18.7 3.0 0.35 10.8 0.1 3.6 3 0 0 3 3 3 2 BNR/Asp-box repeat DUF2433 PF10360.4 KUM62950.1 - 4e-51 172.7 0.0 6.2e-51 172.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.2 KUM62950.1 - 0.002 17.9 0.0 0.0048 16.7 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KUM62950.1 - 0.0054 16.1 0.0 0.011 15.1 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2360 PF10152.4 KUM62950.1 - 0.042 14.1 2.3 0.72 10.1 1.6 2.5 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Aldo_ket_red PF00248.16 KUM62951.1 - 3.7e-48 163.7 0.0 4.5e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Pro-kuma_activ PF09286.6 KUM62952.1 - 2e-46 157.6 0.1 3.7e-46 156.7 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KUM62952.1 - 2.8e-07 29.9 0.8 4.8e-07 29.2 0.5 1.2 1 0 0 1 1 1 1 Subtilase family Response_reg PF00072.19 KUM62953.1 - 6.4e-25 87.3 0.7 1.3e-24 86.3 0.2 1.7 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 KUM62953.1 - 1.1e-22 79.8 0.0 2.2e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 KUM62953.1 - 5.1e-21 74.9 0.0 9e-16 58.1 0.0 2.5 2 0 0 2 2 2 2 PAS domain HisKA PF00512.20 KUM62953.1 - 1.7e-17 63.1 0.1 3.8e-17 62.0 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 KUM62953.1 - 9.3e-12 44.7 0.0 1.6e-07 31.0 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 KUM62953.1 - 1.3e-10 41.2 0.0 9.4e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 PAS fold DAO PF01266.19 KUM62954.1 - 3.2e-20 72.3 0.3 1.1e-18 67.3 0.2 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KUM62954.1 - 0.0061 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF604 PF04646.7 KUM62954.1 - 0.0067 15.6 0.2 0.01 15.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 ApbA PF02558.11 KUM62954.1 - 0.0086 15.5 0.4 0.021 14.2 0.3 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 KUM62954.1 - 0.031 13.1 0.2 0.051 12.4 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A ThiF PF00899.16 KUM62954.1 - 0.038 13.8 0.1 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 ThiF family NAD_binding_8 PF13450.1 KUM62954.1 - 0.04 13.9 0.2 0.11 12.4 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 KUM62954.1 - 0.064 12.9 0.1 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 KUM62954.1 - 0.16 11.0 0.3 0.23 10.4 0.2 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase Zn_clus PF00172.13 KUM62957.1 - 0.0026 17.6 4.9 0.004 17.0 3.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Recep_L_domain PF01030.19 KUM62958.1 - 7.8e-07 29.0 0.3 0.00059 19.7 0.2 3.1 1 1 0 1 1 1 1 Receptor L domain Ecm33 PF12454.3 KUM62958.1 - 0.00039 20.2 0.8 0.00039 20.2 0.6 2.1 2 0 0 2 2 2 1 GPI-anchored cell wall organization protein VSP PF03302.8 KUM62958.1 - 0.0024 16.5 0.4 0.0024 16.5 0.3 1.5 2 0 0 2 2 2 1 Giardia variant-specific surface protein Herpes_gE PF02480.11 KUM62958.1 - 0.0033 15.7 0.0 0.0046 15.2 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 KUM62958.1 - 0.023 14.0 4.8 0.023 14.0 3.4 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Lamp PF01299.12 KUM62958.1 - 0.026 13.6 0.1 0.042 12.9 0.1 1.3 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) RCR PF12273.3 KUM62958.1 - 0.04 14.4 0.0 0.063 13.8 0.0 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF4381 PF14316.1 KUM62958.1 - 0.16 12.0 0.9 0.23 11.5 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Syndecan PF01034.15 KUM62958.1 - 0.16 11.6 0.7 0.36 10.5 0.5 1.5 1 0 0 1 1 1 0 Syndecan domain P12 PF12669.2 KUM62958.1 - 0.31 11.2 1.7 2.2 8.5 0.3 2.4 2 0 0 2 2 2 0 Virus attachment protein p12 family Lipase_GDSL_2 PF13472.1 KUM62959.1 - 1.1e-18 68.0 2.7 1.3e-18 67.7 1.9 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KUM62959.1 - 4.7e-13 49.4 1.2 6.3e-13 49.0 0.8 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Cas_GSU0053 PF09617.5 KUM62959.1 - 0.024 14.4 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) Amidase PF01425.16 KUM62960.1 - 7e-87 292.1 0.0 8.2e-87 291.8 0.0 1.0 1 0 0 1 1 1 1 Amidase PEX11 PF05648.9 KUM62961.1 - 1.9e-35 122.1 0.1 2.2e-35 121.9 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) F-actin_cap_A PF01267.12 KUM62962.1 - 3.1e-92 308.4 0.0 3.5e-92 308.2 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Med7 PF05983.6 KUM62963.1 - 1.7e-58 196.9 2.8 2.1e-58 196.6 1.9 1.1 1 0 0 1 1 1 1 MED7 protein DUF4337 PF14235.1 KUM62963.1 - 3.8 7.3 5.4 3.8 7.3 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Fungal_trans PF04082.13 KUM62964.1 - 9.8e-14 50.8 0.1 1.6e-13 50.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.3 KUM62964.1 - 0.0015 17.2 0.6 0.0085 14.7 0.4 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain tRNA-synt_2c PF01411.14 KUM62965.1 - 5.6e-11 41.4 0.1 7.6e-11 41.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KUM62965.1 - 5.8e-06 26.0 0.2 1.1e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain PAP2 PF01569.16 KUM62966.1 - 6.3e-24 84.0 1.1 6.3e-24 84.0 0.7 2.1 2 1 0 2 2 2 1 PAP2 superfamily DUF2933 PF11666.3 KUM62966.1 - 0.038 13.5 0.1 0.038 13.5 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2933) UPF0546 PF10639.4 KUM62966.1 - 0.085 12.6 0.2 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0546 RseC_MucC PF04246.7 KUM62966.1 - 0.98 8.9 7.9 11 5.5 0.3 3.2 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC MNHE PF01899.11 KUM62966.1 - 2.2 7.9 8.0 26 4.4 0.4 3.1 2 1 1 3 3 3 0 Na+/H+ ion antiporter subunit Cu_amine_oxid PF01179.15 KUM62968.1 - 9.6e-165 548.2 0.0 1.2e-164 548.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 KUM62968.1 - 9.3e-10 38.4 0.1 1.7e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 KUM62968.1 - 0.00037 20.4 0.2 0.0009 19.2 0.0 1.7 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain RVT_1 PF00078.22 KUM62968.1 - 0.17 11.2 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Fungal_trans_2 PF11951.3 KUM62970.1 - 5.9e-78 262.1 0.9 7e-78 261.8 0.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain ParA PF10609.4 KUM62971.1 - 2.2e-33 113.9 0.1 3.8e-33 113.2 0.1 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KUM62971.1 - 0.00014 21.3 0.0 0.0002 20.8 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AATF-Che1 PF13339.1 KUM62973.1 - 4e-32 111.1 1.5 4e-32 111.1 1.0 2.8 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor TRAUB PF08164.7 KUM62973.1 - 7.8e-32 109.2 0.0 7.8e-32 109.2 0.0 2.9 3 1 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AAA_31 PF13614.1 KUM62974.1 - 9.3e-05 22.4 0.1 0.0015 18.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain CbiA PF01656.18 KUM62974.1 - 0.002 17.5 2.8 0.012 15.0 1.9 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MutL PF13941.1 KUM62974.1 - 0.077 11.2 0.0 0.082 11.2 0.0 1.0 1 0 0 1 1 1 0 MutL protein MipZ PF09140.6 KUM62974.1 - 0.17 10.9 0.5 0.27 10.2 0.3 1.4 1 1 0 1 1 1 0 ATPase MipZ GFO_IDH_MocA PF01408.17 KUM62976.1 - 4.4e-23 82.0 0.2 7.1e-23 81.4 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KUM62976.1 - 1.5e-06 27.9 0.0 2.9e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DapB_N PF01113.15 KUM62976.1 - 0.0017 18.2 0.0 0.028 14.3 0.0 2.4 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus DUF1793 PF08760.6 KUM62977.1 - 1.4e-51 174.7 0.0 2.9e-51 173.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) GBA2_N PF12215.3 KUM62977.1 - 0.013 14.6 0.1 0.065 12.3 0.0 2.2 2 1 0 2 2 2 0 beta-Glucocerebrosidase 2 N terminal PAP1 PF08601.5 KUM62978.1 - 9.6e-83 278.7 17.8 9.6e-83 278.7 12.4 2.7 3 1 0 3 3 3 1 Transcription factor PAP1 bZIP_1 PF00170.16 KUM62978.1 - 8.6e-09 35.2 8.1 1.6e-08 34.3 5.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor MbeD_MobD PF04899.7 KUM62978.1 - 0.0012 18.7 1.9 0.0024 17.7 1.3 1.5 1 0 0 1 1 1 1 MbeD/MobD like bZIP_Maf PF03131.12 KUM62978.1 - 0.022 15.0 9.4 0.044 14.0 6.5 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor Glutaredoxin2_C PF04399.8 KUM62978.1 - 0.23 11.0 0.6 0.42 10.1 0.4 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain bZIP_2 PF07716.10 KUM62978.1 - 0.32 10.8 14.0 2.1 8.2 9.7 2.1 1 1 0 1 1 1 0 Basic region leucine zipper IncA PF04156.9 KUM62978.1 - 0.75 9.3 5.3 1.5 8.3 3.7 1.4 1 0 0 1 1 1 0 IncA protein FlxA PF14282.1 KUM62979.1 - 0.012 15.5 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 FlxA-like protein DUF4537 PF15057.1 KUM62979.1 - 0.021 14.6 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) TUDOR PF00567.19 KUM62979.1 - 0.1 12.4 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Tudor domain Patched PF02460.13 KUM62980.1 - 3.8e-75 253.3 13.1 9.2e-74 248.7 9.5 2.0 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 KUM62980.1 - 5e-50 168.9 7.8 5e-50 168.9 5.4 3.6 3 1 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 KUM62980.1 - 2.5e-06 26.4 8.6 2.5e-06 26.4 6.0 3.8 4 1 0 4 4 4 1 MMPL family HEAT PF02985.17 KUM62981.1 - 6.5e-20 69.3 8.1 3.3e-05 23.6 0.1 9.5 11 0 0 11 11 10 5 HEAT repeat HEAT_2 PF13646.1 KUM62981.1 - 2.6e-19 69.2 9.2 4e-07 30.2 0.1 7.4 6 2 2 8 8 8 4 HEAT repeats HEAT_EZ PF13513.1 KUM62981.1 - 2.8e-18 65.8 5.2 1.7e-05 25.1 0.0 9.5 9 3 2 12 12 10 4 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KUM62981.1 - 6.5e-12 45.6 0.7 0.05 13.9 0.0 6.4 5 1 1 6 6 6 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 KUM62981.1 - 3.7e-09 36.6 3.1 0.062 13.1 1.3 4.6 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.14 KUM62981.1 - 4.8e-09 35.9 5.7 6.9e-08 32.2 0.2 3.7 4 0 0 4 4 4 1 Importin-beta N-terminal domain CLASP_N PF12348.3 KUM62981.1 - 8e-07 28.6 0.0 0.0011 18.3 0.0 3.5 3 0 0 3 3 3 2 CLASP N terminal MMS19_C PF12460.3 KUM62981.1 - 1.8e-05 23.6 2.9 0.0013 17.5 0.0 3.6 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal UME PF08064.8 KUM62981.1 - 3.8e-05 23.6 0.1 4.6 7.2 0.1 5.9 4 3 2 6 6 6 2 UME (NUC010) domain Arm PF00514.18 KUM62981.1 - 0.00015 21.4 3.1 1 9.2 0.0 6.1 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat ParcG PF10274.4 KUM62981.1 - 0.0027 17.6 1.6 0.71 9.7 0.1 3.5 3 1 1 4 4 4 1 Parkin co-regulated protein V-ATPase_H_C PF11698.3 KUM62981.1 - 0.067 13.1 1.8 15 5.5 0.0 4.1 4 0 0 4 4 4 0 V-ATPase subunit H Tyrosinase PF00264.15 KUM62982.1 - 2.1e-54 185.0 6.7 3.6e-54 184.2 4.6 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Gal-bind_lectin PF00337.17 KUM62982.1 - 7.1e-11 41.5 0.0 1.6e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Galactoside-binding lectin Amidohydro_1 PF01979.15 KUM62983.1 - 2.2e-33 116.3 0.0 3.3e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KUM62983.1 - 1e-07 31.5 0.3 4.7e-05 22.7 0.0 2.5 2 1 1 3 3 3 2 Amidohydrolase family Amidohydro_4 PF13147.1 KUM62983.1 - 4e-05 23.8 0.5 0.00038 20.5 0.4 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KUM62983.1 - 0.00012 21.8 0.0 0.00028 20.6 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 KUM62983.1 - 0.0065 15.4 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Adenosine/AMP deaminase OPT PF03169.10 KUM62984.1 - 2e-163 545.1 57.7 2.3e-163 544.9 40.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Reticulon PF02453.12 KUM62984.1 - 1.8 8.1 11.6 0.058 13.0 2.2 2.7 3 0 0 3 3 3 0 Reticulon 2-Hacid_dh_C PF02826.14 KUM62985.1 - 8.7e-46 155.2 0.0 1.3e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KUM62985.1 - 4.1e-07 29.5 0.0 5.2e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KUM62985.1 - 0.0036 17.1 0.1 0.0058 16.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Acetyltransf_7 PF13508.1 KUM62986.1 - 1.5e-08 34.6 0.0 6.1e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KUM62986.1 - 1.4e-06 28.2 0.0 2.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KUM62986.1 - 2.1e-05 24.5 0.0 4.2e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KUM62986.1 - 0.00024 20.9 0.0 0.0014 18.4 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain EFhand_Ca_insen PF08726.5 KUM62986.1 - 0.0063 16.4 0.1 0.024 14.5 0.0 1.9 2 0 0 2 2 2 1 Ca2+ insensitive EF hand Glyco_hydro_25 PF01183.15 KUM62989.1 - 9.6e-40 136.3 0.1 1.1e-39 136.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Fungal_trans PF04082.13 KUM62990.1 - 2.9e-23 82.0 0.0 6.1e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM62990.1 - 9.1e-10 38.2 9.5 1.4e-09 37.7 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 KUM62991.1 - 2.4e-35 121.9 0.0 3e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KUM62993.1 - 1.8e-63 214.7 0.0 2e-63 214.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1275 PF06912.6 KUM62994.1 - 0.28 10.3 6.7 3.2 6.9 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1275) DUF3754 PF12576.3 KUM62994.1 - 0.32 10.6 1.8 5.1 6.7 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3754) DUF2678 PF10856.3 KUM62994.1 - 1.6 8.4 7.6 0.28 10.9 2.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2678) DUF3139 PF11337.3 KUM62994.1 - 3.9 7.8 5.5 0.63 10.3 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Wzy_C PF04932.10 KUM62994.1 - 4.5 7.0 7.9 2.2 8.0 1.9 2.0 2 0 0 2 2 2 0 O-Antigen ligase LDB19 PF13002.2 KUM62995.1 - 3.2e-58 196.3 0.0 4.7e-58 195.8 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 KUM62995.1 - 5.3e-07 29.5 0.0 2.2e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain PIG-L PF02585.12 KUM62996.1 - 1.3e-28 100.0 0.0 2.6e-28 99.0 0.0 1.5 2 0 0 2 2 2 1 GlcNAc-PI de-N-acetylase Thioredoxin_7 PF13899.1 KUM62997.1 - 8.3e-15 54.5 0.0 1.8e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 KUM62997.1 - 3.7e-13 48.7 0.0 7.8e-13 47.7 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 KUM62997.1 - 1e-09 38.3 0.0 1.1e-08 34.9 0.0 2.3 3 0 0 3 3 3 1 UBX domain Thioredoxin_2 PF13098.1 KUM62997.1 - 0.014 15.5 0.0 0.053 13.7 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredox_DsbH PF03190.10 KUM62997.1 - 0.014 15.0 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 CENP-K PF11802.3 KUM62997.1 - 0.11 11.7 0.1 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Centromere-associated protein K AAA_16 PF13191.1 KUM62998.1 - 2.1e-11 44.1 0.3 7.8e-11 42.2 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 KUM62998.1 - 9.7e-11 41.9 0.0 5.9e-10 39.4 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KUM62998.1 - 3.8e-10 40.0 0.0 9.1e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Cdc6_C PF09079.6 KUM62998.1 - 2.4e-06 27.1 0.0 6.6e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 CDC6, C terminal NTPase_1 PF03266.10 KUM62998.1 - 0.00069 19.3 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 NTPase KTI12 PF08433.5 KUM62998.1 - 0.00098 18.4 0.3 0.06 12.5 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Arch_ATPase PF01637.13 KUM62998.1 - 0.0074 16.0 0.0 0.019 14.6 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase PIF1 PF05970.9 KUM62998.1 - 0.0088 15.0 0.0 0.023 13.6 0.0 1.6 2 0 0 2 2 2 1 PIF1-like helicase AAA_17 PF13207.1 KUM62998.1 - 0.014 16.1 0.0 0.027 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 KUM62998.1 - 0.016 13.9 0.0 0.03 13.0 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus RNA_helicase PF00910.17 KUM62998.1 - 0.024 14.7 0.0 0.057 13.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 KUM62998.1 - 0.026 14.8 0.0 0.19 12.0 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_14 PF13173.1 KUM62998.1 - 0.035 14.0 0.0 0.082 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 KUM62998.1 - 0.051 12.2 0.0 0.086 11.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF815 PF05673.8 KUM62998.1 - 0.079 11.8 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.9 KUM62998.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) GTP_EFTU PF00009.22 KUM62999.1 - 3.3e-21 75.5 0.1 6.4e-21 74.6 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KUM62999.1 - 3.1e-14 52.9 0.0 6.5e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KUM62999.1 - 6.1e-07 29.4 1.9 2.7e-06 27.4 1.4 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 KUM62999.1 - 0.0035 16.8 0.4 0.52 9.7 0.0 3.1 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 KUM62999.1 - 0.14 12.6 0.4 1.5 9.3 0.3 2.6 1 1 0 1 1 1 0 Miro-like protein COG6 PF06419.6 KUM62999.1 - 0.21 9.6 0.0 0.32 9.0 0.0 1.2 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 EVI2A PF05399.6 KUM63000.1 - 0.088 12.0 2.8 0.11 11.7 2.0 1.3 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) ATP13 PF12921.2 KUM63001.1 - 3.2e-25 87.9 0.0 7.8e-25 86.6 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_2 PF13041.1 KUM63001.1 - 0.011 15.6 0.0 10 6.1 0.0 3.6 3 0 0 3 3 3 0 PPR repeat family LSM PF01423.17 KUM63002.1 - 9.8e-15 53.8 0.3 1.4e-14 53.3 0.2 1.2 1 0 0 1 1 1 1 LSM domain Pkinase PF00069.20 KUM63003.1 - 3.7e-48 163.9 0.0 5.7e-48 163.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM63003.1 - 3.7e-32 111.4 0.0 8.6e-32 110.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM63003.1 - 8.8e-06 24.8 0.0 1.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF1479 PF07350.7 KUM63005.1 - 0.015 13.8 0.0 0.75 8.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1479) F-box-like PF12937.2 KUM63008.1 - 2.9e-05 23.6 0.9 6.9e-05 22.4 0.1 2.1 2 0 0 2 2 2 1 F-box-like PalH PF08733.5 KUM63009.1 - 1.4e-105 352.9 0.0 1.3e-104 349.8 0.0 1.9 1 1 0 1 1 1 1 PalH/RIM21 DUF4231 PF14015.1 KUM63009.1 - 0.18 11.7 1.7 3.5 7.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Asp PF00026.18 KUM63010.1 - 2.6e-72 243.7 4.8 3.3e-72 243.4 3.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KUM63010.1 - 0.0003 21.2 1.6 0.17 12.4 0.3 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KUM63010.1 - 0.015 14.8 0.0 0.062 12.8 0.0 2.2 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Corona_3 PF04694.7 KUM63010.1 - 0.11 12.4 0.0 0.33 10.8 0.0 1.8 1 0 0 1 1 1 0 Coronavirus ORF3 protein RecR PF02132.10 KUM63013.1 - 0.35 10.3 2.1 0.84 9.1 1.0 1.9 2 0 0 2 2 2 0 RecR protein DIT1_PvcA PF05141.7 KUM63014.1 - 3.3e-12 46.3 0.0 4.1e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein EF1_GNE PF00736.14 KUM63015.1 - 1.4e-31 108.0 2.0 2.1e-31 107.4 1.4 1.2 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 KUM63015.1 - 2.2e-13 50.0 8.1 2.2e-13 50.0 5.6 2.6 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region MinC_N PF05209.8 KUM63015.1 - 0.024 14.3 0.0 0.057 13.1 0.0 1.5 1 1 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain YL1 PF05764.8 KUM63015.1 - 0.031 13.8 1.2 0.048 13.2 0.8 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DUF3752 PF12572.3 KUM63015.1 - 0.12 12.5 1.6 0.19 11.8 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) DNA_pol_A PF00476.15 KUM63016.1 - 7.9e-99 330.8 0.0 1.2e-98 330.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DUF1454 PF07305.7 KUM63016.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) CorA PF01544.13 KUM63017.1 - 2e-25 89.4 8.2 5.4e-18 65.0 0.5 3.2 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein UPF0052 PF01933.13 KUM63018.1 - 3.4e-55 187.4 0.0 4.5e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 zf-C3HC4_2 PF13923.1 KUM63019.1 - 0.0061 16.5 0.5 0.01 15.8 0.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Adeno_PIX PF03955.9 KUM63019.1 - 0.08 13.4 0.3 0.12 12.9 0.2 1.3 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) zf-C3HC4_3 PF13920.1 KUM63019.1 - 0.13 11.9 0.2 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPT PF03151.11 KUM63020.1 - 4.4e-29 101.0 8.5 4.4e-29 101.0 5.9 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KUM63020.1 - 3.9e-07 29.3 18.1 1.3e-05 24.3 12.5 2.2 1 1 0 1 1 1 1 UAA transporter family DUF914 PF06027.7 KUM63020.1 - 0.21 10.3 12.7 0.67 8.7 8.1 2.2 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) MFS_1 PF07690.11 KUM63021.1 - 3.1e-19 68.9 14.0 3.1e-19 68.9 9.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3145 PF11343.3 KUM63022.1 - 0.064 12.6 0.0 0.22 10.9 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3145) Methyltransf_PK PF05891.7 KUM63023.1 - 1.4e-69 233.6 0.0 1.7e-69 233.4 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 KUM63023.1 - 0.001 18.8 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM63023.1 - 0.0053 17.3 0.0 0.0085 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain SQS_PSY PF00494.14 KUM63024.1 - 8e-42 143.3 0.0 1.1e-41 142.9 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase SNF2_N PF00176.18 KUM63025.1 - 8.5e-69 231.6 0.0 1.2e-68 231.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 KUM63025.1 - 1.1e-22 80.0 0.0 9e-22 77.0 0.0 2.3 2 0 0 2 2 2 1 HIRAN domain Helicase_C PF00271.26 KUM63025.1 - 2.7e-13 49.5 0.0 9.3e-13 47.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 KUM63025.1 - 1.2e-06 28.4 11.8 2.4e-06 27.4 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KUM63025.1 - 5.6e-05 22.7 9.2 9.8e-05 21.9 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KUM63025.1 - 0.0023 17.7 10.4 0.0046 16.7 7.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KUM63025.1 - 0.0059 16.2 12.1 0.011 15.3 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KUM63025.1 - 0.0069 16.0 10.7 0.013 15.2 7.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain PLU-1 PF08429.6 KUM63025.1 - 0.012 14.5 0.4 0.021 13.7 0.3 1.3 1 0 0 1 1 1 0 PLU-1-like protein zf-RING_UBOX PF13445.1 KUM63025.1 - 0.32 10.7 8.5 0.81 9.4 5.9 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KUM63025.1 - 1.1 9.2 11.0 2.2 8.2 7.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING MFS_1 PF07690.11 KUM63026.1 - 4.5e-32 111.1 83.5 3.5e-28 98.3 43.6 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KUM63026.1 - 0.00024 19.6 5.6 0.00024 19.6 3.9 4.7 1 1 2 4 4 4 2 MFS/sugar transport protein VPEP PF07589.6 KUM63026.1 - 3.6 7.6 0.0 3.6 7.6 0.0 5.1 5 0 0 5 5 5 0 PEP-CTERM motif Zn_clus PF00172.13 KUM63027.1 - 8.4e-10 38.4 7.8 8.4e-10 38.4 5.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KUM63027.1 - 2.2e-07 30.0 3.1 3.9e-07 29.2 2.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fer4_4 PF12800.2 KUM63027.1 - 8.6 6.9 11.0 1.2 9.6 0.1 2.8 2 1 0 2 2 2 0 4Fe-4S binding domain RVT_2 PF07727.9 KUM63029.1 - 0.0049 15.8 0.0 0.0067 15.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Zn_clus PF00172.13 KUM63031.1 - 4.6e-07 29.6 14.8 6.9e-07 29.0 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.16 KUM63032.1 - 5.2e-13 48.9 0.0 7.6e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KUM63032.1 - 3.5e-09 36.9 0.0 5.5e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KUM63032.1 - 5.7e-07 28.5 0.0 9.6e-07 27.7 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KUM63032.1 - 2e-06 27.2 0.1 0.00012 21.3 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.12 KUM63032.1 - 6.9e-05 21.8 0.0 0.21 10.4 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain adh_short PF00106.20 KUM63032.1 - 0.0014 18.5 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Glyco_hydro_47 PF01532.15 KUM63033.1 - 6.1e-173 575.6 0.3 7.1e-173 575.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyoxal_oxid_N PF07250.6 KUM63033.1 - 0.021 13.8 0.4 0.065 12.2 0.0 1.8 2 0 0 2 2 2 0 Glyoxal oxidase N-terminus DUF1680 PF07944.7 KUM63033.1 - 0.023 13.0 0.1 3.5 5.7 0.0 2.1 2 0 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) Med20 PF08612.6 KUM63034.1 - 6.9e-79 264.1 0.0 7.9e-79 263.9 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Clathrin_lg_ch PF01086.12 KUM63036.1 - 1.5e-71 240.9 3.8 1.8e-71 240.6 2.6 1.1 1 0 0 1 1 1 1 Clathrin light chain HrpF PF06266.7 KUM63036.1 - 4.6 7.4 6.2 0.72 10.0 1.1 1.9 2 0 0 2 2 2 0 HrpF protein CTD_bind PF04818.8 KUM63037.1 - 4.8e-19 68.3 0.3 1.1e-18 67.1 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF869 PF05911.6 KUM63037.1 - 0.0026 16.0 0.8 0.0033 15.7 0.6 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) DUF3277 PF11681.3 KUM63037.1 - 0.0097 15.3 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3277) MxiH PF09392.5 KUM63037.1 - 0.039 14.5 0.0 2.4 8.7 0.0 2.8 2 1 0 2 2 2 0 Type III secretion needle MxiH like Muted PF14942.1 KUM63037.1 - 0.052 13.4 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Glyco_hydro_31 PF01055.21 KUM63038.1 - 5.8e-170 565.8 1.9 7.1e-170 565.5 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KUM63038.1 - 0.00019 21.2 0.6 0.00094 18.9 0.2 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like GHL15 PF14885.1 KUM63038.1 - 0.14 12.3 4.6 0.038 14.1 0.7 1.9 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase family 15 SOG2 PF10428.4 KUM63038.1 - 0.42 9.2 0.9 0.64 8.6 0.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Fungal_trans PF04082.13 KUM63039.1 - 4.7e-20 71.5 0.1 6.8e-20 71.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_23 PF13489.1 KUM63040.1 - 1.2e-17 64.1 0.0 1.7e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM63040.1 - 3.7e-11 43.3 0.0 6.2e-10 39.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM63040.1 - 4.6e-11 43.0 0.0 1.3e-10 41.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM63040.1 - 1.7e-09 38.2 0.0 2.6e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM63040.1 - 1.2e-08 34.6 0.0 8.6e-05 22.1 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 KUM63040.1 - 1.3e-05 25.1 0.0 2.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM63040.1 - 0.0001 22.6 0.0 0.00028 21.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Prp18 PF02840.10 KUM63040.1 - 0.076 12.8 0.2 0.11 12.2 0.2 1.4 1 1 0 1 1 1 0 Prp18 domain ABC_membrane PF00664.18 KUM63041.1 - 2.2e-46 158.5 10.5 3.1e-46 158.0 7.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KUM63041.1 - 1.5e-36 125.7 0.0 3.7e-36 124.4 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KUM63041.1 - 1.2e-05 24.6 0.0 0.00094 18.4 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KUM63041.1 - 9.4e-05 22.5 0.1 0.15 12.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KUM63041.1 - 0.0018 17.7 0.0 0.0049 16.3 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.12 KUM63041.1 - 0.0047 16.3 0.1 0.076 12.4 0.0 2.5 2 1 1 3 3 3 1 IstB-like ATP binding protein ABC_ATPase PF09818.4 KUM63041.1 - 0.01 14.4 0.4 0.048 12.2 0.1 1.9 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA PF00004.24 KUM63041.1 - 0.011 15.9 0.0 0.051 13.7 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KUM63041.1 - 0.012 15.6 0.7 0.072 13.0 0.5 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 KUM63041.1 - 0.012 15.0 0.1 0.049 13.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KUM63041.1 - 0.014 16.1 0.0 0.03 15.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KUM63041.1 - 0.016 15.3 0.2 0.11 12.6 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KUM63041.1 - 0.046 13.1 0.1 0.17 11.3 0.1 1.9 2 0 0 2 2 2 0 AAA-like domain DUF258 PF03193.11 KUM63041.1 - 0.046 12.9 0.0 0.097 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Gtr1_RagA PF04670.7 KUM63041.1 - 0.069 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_18 PF13238.1 KUM63041.1 - 0.075 13.3 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 KUM63041.1 - 0.13 12.1 4.2 0.21 11.5 0.4 3.2 4 1 0 4 4 2 0 Putative exonuclease SbcCD, C subunit MobB PF03205.9 KUM63041.1 - 0.16 11.7 0.0 0.4 10.3 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CDC37_N PF03234.9 KUM63042.1 - 1e-60 205.0 3.5 1e-60 205.0 2.4 2.5 2 1 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 KUM63042.1 - 1.1e-46 158.5 0.1 2.7e-46 157.2 0.0 1.7 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 KUM63042.1 - 9.9e-27 92.7 1.3 9.9e-27 92.7 0.9 3.0 3 1 0 3 3 3 1 Cdc37 C terminal domain DUF922 PF06037.6 KUM63042.1 - 0.022 14.1 0.3 0.12 11.6 0.0 2.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF922) MutS_IV PF05190.13 KUM63042.1 - 0.5 10.5 6.3 2 8.6 0.2 3.1 3 0 0 3 3 3 0 MutS family domain IV Rsbr_N PF08678.5 KUM63042.1 - 0.67 9.8 3.6 12 5.7 0.3 3.2 3 0 0 3 3 3 0 Rsbr N terminal SNARE PF05739.14 KUM63043.1 - 5.3e-17 61.2 4.3 1.2e-16 60.0 1.8 2.5 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KUM63043.1 - 4.9e-13 49.1 0.3 4.9e-13 49.1 0.2 2.5 1 1 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.1 KUM63043.1 - 0.023 14.7 10.0 0.027 14.4 0.2 3.4 2 2 1 3 3 3 0 Syntaxin-like protein Cauli_DNA-bind PF03310.8 KUM63043.1 - 0.1 12.4 1.5 0.97 9.2 0.2 2.4 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein MCPsignal PF00015.16 KUM63043.1 - 0.24 10.9 11.9 0.11 11.9 2.1 2.8 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DNA_repr_REX1B PF14966.1 KUM63043.1 - 0.65 10.4 0.1 0.65 10.4 0.0 2.9 4 1 0 4 4 4 0 DNA repair REX1-B BBP1_C PF15272.1 KUM63043.1 - 0.96 8.9 11.1 2.3 7.7 0.4 3.2 1 1 1 3 3 3 0 Spindle pole body component BBP1, C-terminal H-kinase_dim PF02895.9 KUM63043.1 - 9.2 6.6 9.4 7.9 6.9 1.0 2.9 3 0 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain EF-hand_1 PF00036.27 KUM63044.1 - 3.6e-22 75.9 2.9 3.2e-10 38.5 0.6 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KUM63044.1 - 8.1e-21 73.9 1.5 1.1e-20 73.5 1.1 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 KUM63044.1 - 3.2e-20 71.4 4.4 1.3e-16 59.9 0.5 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KUM63044.1 - 4.6e-16 57.1 0.6 2.1e-09 36.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 KUM63044.1 - 5.2e-14 50.8 1.3 1.4e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 EF hand EFhand_Ca_insen PF08726.5 KUM63044.1 - 4.4e-07 29.7 0.4 6.3e-07 29.2 0.2 1.3 1 0 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_9 PF14658.1 KUM63044.1 - 1.9e-05 24.4 0.1 2.3e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.2 KUM63044.1 - 8.1e-05 22.3 0.4 9.8e-05 22.0 0.3 1.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KUM63044.1 - 0.00066 19.6 0.1 0.00078 19.4 0.1 1.1 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 KUM63044.1 - 0.0013 18.3 0.2 0.016 14.7 0.0 2.2 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0154) EF-hand_10 PF14788.1 KUM63044.1 - 0.053 13.2 0.5 0.19 11.4 0.1 2.0 1 1 1 2 2 2 0 EF hand TerB PF05099.8 KUM63044.1 - 0.089 12.5 0.3 0.19 11.4 0.1 1.6 1 1 1 2 2 2 0 Tellurite resistance protein TerB Homeobox_KN PF05920.6 KUM63045.1 - 2.9e-20 71.7 0.3 5.5e-20 70.7 0.2 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KUM63045.1 - 4.9e-07 29.2 0.1 8.1e-07 28.5 0.1 1.3 1 0 0 1 1 1 1 Homeobox domain M_domain PF12938.2 KUM63046.1 - 1.3 8.7 4.5 1.8 8.2 3.1 1.3 1 0 0 1 1 1 0 M domain of GW182 Alpha-amylase PF00128.19 KUM63047.1 - 5.5e-73 246.1 4.0 7.3e-73 245.7 2.8 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 KUM63047.1 - 6e-19 67.9 0.3 1.6e-18 66.5 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) hDGE_amylase PF14701.1 KUM63047.1 - 0.017 14.0 0.0 0.034 13.0 0.0 1.5 2 0 0 2 2 2 0 glucanotransferase domain of human glycogen debranching enzyme CPSase_L_D2 PF02786.12 KUM63049.1 - 6.4e-36 123.6 0.0 1.1e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KUM63049.1 - 6.7e-35 119.5 0.0 1.3e-34 118.6 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 KUM63049.1 - 4e-07 29.0 0.0 7.6e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KUM63049.1 - 4.3e-07 29.5 0.0 7.4e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.1 KUM63049.1 - 6.6e-07 29.2 0.0 1.3e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KUM63049.1 - 9e-05 22.0 0.0 0.00018 21.0 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Metallophos PF00149.23 KUM63050.1 - 3.7e-36 124.4 0.3 5.7e-36 123.8 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FAD_binding_1 PF00667.15 KUM63051.1 - 1.3e-43 148.9 0.0 1.9e-43 148.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KUM63051.1 - 5.1e-10 39.8 0.0 1.1e-09 38.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain AA_permease_2 PF13520.1 KUM63052.1 - 4.4e-52 177.0 45.7 5.3e-52 176.7 31.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM63052.1 - 6.8e-24 84.0 38.5 9.2e-24 83.6 26.7 1.0 1 0 0 1 1 1 1 Amino acid permease Amidase PF01425.16 KUM63053.1 - 2.2e-74 250.9 0.0 1.7e-64 218.3 0.0 2.0 1 1 1 2 2 2 2 Amidase CstA PF02554.9 KUM63055.1 - 0.066 11.8 10.6 1.1 7.8 7.3 2.0 1 1 0 1 1 1 0 Carbon starvation protein CstA Nitroreductase PF00881.19 KUM63056.1 - 3.7e-16 59.3 0.0 4.8e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family DUF1682 PF07946.9 KUM63057.1 - 2.5e-110 368.2 0.0 3e-110 368.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Ada3 PF10198.4 KUM63057.1 - 0.28 10.9 7.0 0.42 10.3 4.9 1.3 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 Polysacc_deac_1 PF01522.16 KUM63058.1 - 3.9e-18 65.2 0.1 5.8e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Creatininase PF02633.9 KUM63058.1 - 2.6e-05 23.4 0.1 3e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 Creatinine amidohydrolase Nucleoside_tran PF01733.13 KUM63059.1 - 9.2e-44 149.8 12.8 3.8e-42 144.5 8.9 2.5 1 1 0 1 1 1 1 Nucleoside transporter DUF2975 PF11188.3 KUM63059.1 - 7.6 6.2 14.4 0.78 9.4 0.5 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF2975) p450 PF00067.17 KUM63060.1 - 2.7e-75 253.6 0.0 3.2e-75 253.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3635 PF12330.3 KUM63061.1 - 0.0001 22.2 0.2 0.00029 20.8 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3635) DUF2404 PF10296.4 KUM63062.1 - 0.00035 20.6 0.0 0.0011 19.0 0.0 1.9 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Polysacc_deac_1 PF01522.16 KUM63063.1 - 0.054 13.1 0.0 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide deacetylase DUF2064 PF09837.4 KUM63063.1 - 0.087 12.4 0.0 0.18 11.4 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) Zn_clus PF00172.13 KUM63064.1 - 1.3e-07 31.3 6.7 1.3e-07 31.3 4.7 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF836 PF05768.9 KUM63065.1 - 6.7e-14 51.9 0.0 7.8e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 KUM63065.1 - 0.0024 17.8 0.0 0.004 17.1 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 KUM63065.1 - 0.026 14.7 0.0 0.033 14.3 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain CHORD PF04968.7 KUM63066.1 - 6.3e-48 160.8 17.4 9.1e-28 96.3 3.1 3.2 3 0 0 3 3 3 3 CHORD CS PF04969.11 KUM63066.1 - 2.5e-13 50.3 0.0 3.8e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 CS domain DHquinase_II PF01220.14 KUM63067.1 - 5.3e-60 200.7 0.1 6.2e-60 200.5 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II SBF PF01758.11 KUM63068.1 - 6e-43 146.4 13.2 1.3e-23 83.3 1.6 3.5 3 2 1 4 4 4 2 Sodium Bile acid symporter family DUF3425 PF11905.3 KUM63069.1 - 9.6e-23 80.5 0.2 1.9e-22 79.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) TALPID3 PF15324.1 KUM63069.1 - 0.002 15.5 0.4 0.0026 15.2 0.2 1.0 1 0 0 1 1 1 1 Hedgehog signalling target bZIP_1 PF00170.16 KUM63069.1 - 0.028 14.3 4.7 0.046 13.6 3.3 1.3 1 0 0 1 1 1 0 bZIP transcription factor bZIP_Maf PF03131.12 KUM63069.1 - 0.052 13.8 2.0 0.11 12.8 1.4 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Choline_kinase PF01633.15 KUM63070.1 - 9.6e-42 142.9 0.0 3.3e-40 137.9 0.0 2.1 2 0 0 2 2 2 2 Choline/ethanolamine kinase APH PF01636.18 KUM63070.1 - 1.2e-08 34.9 0.5 1.2e-08 34.9 0.3 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Fungal_trans_2 PF11951.3 KUM63071.1 - 4.4e-34 117.7 9.6 7.4e-34 116.9 6.7 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM63071.1 - 7e-07 29.0 9.4 7e-07 29.0 6.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_I PF01487.10 KUM63072.1 - 1.6e-46 158.7 0.0 2.5e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 KUM63072.1 - 6.7e-21 74.7 0.1 1.5e-20 73.6 0.0 1.6 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 KUM63072.1 - 1.3e-18 66.7 0.0 3.6e-18 65.3 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KUM63072.1 - 5.7e-10 39.4 0.1 1.5e-09 38.0 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.1 KUM63072.1 - 0.022 14.6 0.0 0.06 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain F420_oxidored PF03807.12 KUM63072.1 - 0.032 14.6 0.0 0.83 10.1 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AAA_17 PF13207.1 KUM63072.1 - 0.12 13.2 0.0 0.28 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KUM63072.1 - 0.17 12.0 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Fungal_trans PF04082.13 KUM63073.1 - 1.6e-21 76.4 0.2 2.5e-21 75.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM63073.1 - 1.5e-06 27.9 14.5 2.4e-06 27.3 10.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bac_rhamnosid PF05592.6 KUM63074.1 - 2.3e-24 85.4 0.0 5.9e-24 84.1 0.0 1.5 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 KUM63074.1 - 3.4e-07 29.9 0.0 5.9e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Glyco_hydro_2_N PF02837.13 KUM63074.1 - 0.01 15.3 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Sugar_tr PF00083.19 KUM63075.1 - 4.3e-69 233.2 25.5 5e-69 233.0 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM63075.1 - 2.9e-17 62.4 30.6 1.6e-08 33.6 9.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Tetraspannin PF00335.15 KUM63075.1 - 0.0018 17.5 1.6 0.0018 17.5 1.1 2.6 2 0 0 2 2 2 1 Tetraspanin family DUF1680 PF07944.7 KUM63077.1 - 6e-133 443.8 0.2 6.8e-133 443.6 0.1 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_92 PF07971.7 KUM63078.1 - 2e-109 366.5 0.5 2.6e-109 366.1 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Bul1_N PF04425.7 KUM63079.1 - 3.9e-08 32.2 3.5 6.8e-05 21.6 1.0 3.0 2 1 0 2 2 2 2 Bul1 N terminus Bul1_C PF04426.7 KUM63079.1 - 0.00035 19.8 0.1 0.00069 18.8 0.1 1.5 1 0 0 1 1 1 1 Bul1 C terminus Arrestin_N PF00339.24 KUM63079.1 - 0.0034 17.1 0.0 0.027 14.2 0.0 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain PALP PF00291.20 KUM63080.1 - 1.6e-53 181.9 0.0 1.8e-53 181.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme adh_short PF00106.20 KUM63082.1 - 5.1e-10 39.5 0.2 2.7e-09 37.1 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase Metallophos PF00149.23 KUM63083.1 - 4.8e-11 42.4 0.6 1.1e-10 41.2 0.4 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase 14-3-3 PF00244.15 KUM63084.1 - 1.9e-11 43.5 0.2 6.2e-11 41.8 0.0 1.7 2 0 0 2 2 2 1 14-3-3 protein DUF911 PF06023.7 KUM63084.1 - 0.092 11.9 0.2 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 Archaeal protein of unknown function (DUF911) Nucleoside_tran PF01733.13 KUM63084.1 - 0.097 11.8 0.1 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Nucleoside transporter Toxin_15 PF07906.8 KUM63084.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 ShET2 enterotoxin, N-terminal region DivIC PF04977.10 KUM63085.1 - 0.046 13.2 7.2 0.48 9.9 0.7 2.5 1 1 1 2 2 2 0 Septum formation initiator CCDC92 PF14916.1 KUM63085.1 - 0.23 11.0 4.2 0.88 9.2 0.3 2.4 2 0 0 2 2 2 0 Coiled-coil domain of unknown function Mto2_bdg PF12808.2 KUM63085.1 - 0.87 9.7 7.8 0.44 10.6 1.7 2.9 1 1 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Cep57_CLD_2 PF14197.1 KUM63085.1 - 1.6 8.6 15.9 0.45 10.4 8.5 2.0 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF2570 PF10828.3 KUM63085.1 - 2 8.0 7.0 6.5 6.4 4.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) Phage_GP20 PF06810.6 KUM63085.1 - 2.1 7.8 8.2 18 4.7 5.5 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF904 PF06005.7 KUM63085.1 - 3.8 7.8 15.1 4.6e+02 1.1 10.5 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF904) PHD PF00628.24 KUM63085.1 - 4.6 7.0 14.9 8.6 6.1 10.4 1.5 1 0 0 1 1 1 0 PHD-finger AP_endonuc_2 PF01261.19 KUM63086.1 - 3e-27 95.3 0.1 3.9e-27 94.9 0.1 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel FKBP_C PF00254.23 KUM63087.1 - 1.9e-23 82.2 0.0 2.2e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RhoGAP PF00620.22 KUM63088.1 - 4.9e-47 159.3 0.0 1.4e-46 157.8 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 KUM63088.1 - 6.6e-15 54.9 19.4 1.2e-09 38.1 1.8 2.4 2 0 0 2 2 2 2 LIM domain HAUS6_N PF14661.1 KUM63088.1 - 0.02 14.2 1.6 0.046 13.0 1.1 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus CENP-F_leu_zip PF10473.4 KUM63088.1 - 0.039 13.8 12.9 0.093 12.5 2.4 3.1 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CmcI PF04989.7 KUM63088.1 - 0.062 12.6 0.4 0.27 10.5 0.2 2.0 2 0 0 2 2 2 0 Cephalosporin hydroxylase Laminin_II PF06009.7 KUM63088.1 - 0.18 11.5 8.6 1.1 9.0 1.0 2.6 2 0 0 2 2 2 0 Laminin Domain II HAUS-augmin3 PF14932.1 KUM63088.1 - 0.34 10.0 10.6 0.024 13.8 3.0 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF972 PF06156.8 KUM63088.1 - 1.1 9.5 10.7 0.028 14.7 1.1 2.9 3 0 0 3 3 2 0 Protein of unknown function (DUF972) Zn-ribbon_8 PF09723.5 KUM63088.1 - 1.9 8.5 19.8 0.25 11.3 1.1 4.1 3 1 1 4 4 4 0 Zinc ribbon domain ZapA PF05164.8 KUM63088.1 - 2.2 8.2 7.1 10 6.1 4.9 2.1 1 1 0 1 1 1 0 Cell division protein ZapA FlxA PF14282.1 KUM63088.1 - 6 6.8 12.9 5.5 7.0 6.0 2.6 2 0 0 2 2 2 0 FlxA-like protein DUF4407 PF14362.1 KUM63088.1 - 8.2 5.2 7.0 13 4.6 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V-ATPase_C PF03223.10 KUM63089.1 - 1.1e-119 399.7 0.1 1.2e-119 399.5 0.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Inositol_P PF00459.20 KUM63090.1 - 3.9e-80 269.0 0.0 4.4e-80 268.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Shikimate_dh_N PF08501.6 KUM63091.1 - 7.9e-21 73.9 0.0 2.1e-20 72.5 0.0 1.7 1 1 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KUM63091.1 - 1.8e-14 54.0 0.0 2.7e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Methyltransf_26 PF13659.1 KUM63091.1 - 0.09 12.8 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Sugar_tr PF00083.19 KUM63092.1 - 4.5e-136 454.0 20.7 5.1e-136 453.8 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM63092.1 - 8.3e-25 87.2 29.0 8.3e-25 87.2 20.1 2.2 1 1 2 3 3 3 2 Major Facilitator Superfamily GFO_IDH_MocA PF01408.17 KUM63093.1 - 1.8e-27 96.2 0.1 2.6e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KUM63093.1 - 3.4e-17 62.2 0.0 1.4e-16 60.2 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 KUM63093.1 - 5.1e-05 23.5 0.0 8.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_N PF00044.19 KUM63093.1 - 0.0053 16.7 0.0 0.0096 15.8 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain CoA_binding_2 PF13380.1 KUM63093.1 - 0.089 12.9 0.1 0.28 11.3 0.0 1.8 2 0 0 2 2 2 0 CoA binding domain Ldh_1_N PF00056.18 KUM63093.1 - 0.094 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain APS_kinase PF01583.15 KUM63094.1 - 3.9e-72 241.0 0.0 4.7e-72 240.7 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 KUM63094.1 - 5.1e-08 32.9 0.0 7.9e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KUM63094.1 - 1.6e-05 25.2 0.0 3.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KUM63094.1 - 3.7e-05 24.5 0.0 6.8e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KUM63094.1 - 0.0019 18.2 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.5 KUM63094.1 - 0.0021 17.3 0.0 0.0025 17.0 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 KUM63094.1 - 0.052 13.0 0.1 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KUM63094.1 - 0.065 13.3 0.0 0.81 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Hpr_kinase_C PF07475.7 KUM63094.1 - 0.079 12.2 0.0 0.16 11.2 0.0 1.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Zeta_toxin PF06414.7 KUM63094.1 - 0.12 11.5 0.0 0.24 10.4 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin 4HBT PF03061.17 KUM63095.1 - 4.2e-12 46.0 0.0 7.2e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily F-box-like PF12937.2 KUM63096.1 - 0.0048 16.5 0.0 0.008 15.8 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KUM63096.1 - 0.0071 15.9 0.1 0.016 14.8 0.1 1.7 1 1 0 1 1 1 1 F-box domain GPI2 PF06432.6 KUM63097.1 - 3.5e-125 417.0 4.8 4.1e-125 416.7 3.3 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Polysacc_deac_1 PF01522.16 KUM63099.1 - 4.4e-19 68.3 0.0 1e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Nucleoplasmin PF03066.10 KUM63099.1 - 1.3 8.5 3.8 2.3 7.7 2.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin Fringe PF02434.11 KUM63100.1 - 3e-09 36.4 0.0 5.5e-08 32.3 0.0 2.3 2 1 0 2 2 2 1 Fringe-like Glyco_transf_34 PF05637.7 KUM63100.1 - 0.022 14.2 1.0 0.078 12.4 0.3 1.9 2 0 0 2 2 2 0 galactosyl transferase GMA12/MNN10 family PAN_4 PF14295.1 KUM63100.1 - 0.031 13.9 0.4 0.064 12.9 0.3 1.5 1 0 0 1 1 1 0 PAN domain Fumble PF03630.9 KUM63101.1 - 4.2e-136 453.2 0.0 2.6e-135 450.6 0.0 1.9 1 1 0 1 1 1 1 Fumble Hydantoinase_A PF01968.13 KUM63101.1 - 0.11 11.5 0.1 1.4 7.9 0.0 2.1 1 1 0 2 2 2 0 Hydantoinase/oxoprolinase DEAD PF00270.24 KUM63102.1 - 1.1e-39 135.7 0.0 2e-39 134.8 0.0 1.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM63102.1 - 1.8e-19 69.3 1.3 2e-19 69.2 0.1 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KUM63102.1 - 2.7e-06 26.3 0.0 4e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KUM63102.1 - 0.075 12.8 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Abhydrolase_3 PF07859.8 KUM63103.1 - 7.9e-38 130.1 0.0 9.5e-38 129.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KUM63103.1 - 5.7e-06 25.7 0.0 1.4e-05 24.4 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KUM63103.1 - 1.7e-05 24.8 1.2 2.9e-05 24.0 0.9 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KUM63103.1 - 7.5e-05 22.1 0.0 0.032 13.5 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Esterase PF00756.15 KUM63103.1 - 0.00055 19.4 0.0 0.026 13.9 0.0 2.1 2 0 0 2 2 2 1 Putative esterase Abhydrolase_5 PF12695.2 KUM63103.1 - 0.00067 19.4 0.0 0.0011 18.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 KUM63103.1 - 0.0018 17.7 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) AXE1 PF05448.7 KUM63103.1 - 0.0086 14.6 0.0 0.11 10.9 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 KUM63103.1 - 0.074 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DFP PF04127.10 KUM63105.1 - 2.3e-14 53.4 0.0 1.7e-05 24.5 0.0 3.1 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein Acatn PF13000.2 KUM63107.1 - 2.9e-145 484.8 24.4 5.6e-75 252.9 7.0 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 CENP-O PF09496.5 KUM63108.1 - 1.4e-26 92.5 0.0 2.3e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component Lipoxygenase PF00305.14 KUM63111.1 - 4.9e-53 180.1 0.5 1.9e-52 178.1 0.4 1.8 1 1 0 1 1 1 1 Lipoxygenase MFS_1 PF07690.11 KUM63112.1 - 2e-30 105.7 31.6 2.9e-30 105.1 21.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Yae1_N PF09811.4 KUM63114.1 - 3e-10 39.4 0.2 3e-10 39.4 0.1 2.5 2 1 1 3 3 3 1 Essential protein Yae1, N terminal RNase_T PF00929.19 KUM63115.1 - 1.7e-15 57.6 0.0 3e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Exonuclease Med3 PF11593.3 KUM63116.1 - 2.9 7.0 15.8 6.1 5.9 11.0 1.6 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CAF-1_p150 PF11600.3 KUM63116.1 - 3 7.1 33.9 2.8 7.2 6.5 2.4 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Aldedh PF00171.17 KUM63118.1 - 5.4e-152 506.3 0.4 6.1e-152 506.1 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DMRL_synthase PF00885.14 KUM63118.1 - 0.076 12.6 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 6,7-dimethyl-8-ribityllumazine synthase TraC_F_IV PF11130.3 KUM63118.1 - 0.17 11.3 0.0 4.4 6.6 0.0 2.1 2 0 0 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer WD40 PF00400.27 KUM63119.1 - 4.4e-120 387.7 21.3 1.2e-13 50.3 0.0 10.0 9 0 0 9 9 9 9 WD domain, G-beta repeat Amidohydro_2 PF04909.9 KUM63119.1 - 1.3e-21 77.3 0.0 2.2e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Proteasome_A_N PF10584.4 KUM63119.1 - 0.00015 21.0 11.2 0.69 9.2 0.0 7.2 8 0 0 8 8 8 1 Proteasome subunit A N-terminal signature PD40 PF07676.7 KUM63119.1 - 0.00017 21.1 0.1 30 4.4 0.0 5.9 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 KUM63119.1 - 0.0015 17.6 0.2 6.2 5.8 0.0 4.7 1 1 5 6 6 6 1 Protein of unknown function (DUF1258) DUF746 PF05344.6 KUM63119.1 - 0.002 17.6 0.5 0.17 11.4 0.0 3.5 3 0 0 3 3 3 1 Domain of Unknown Function (DUF746) Cytochrom_D1 PF02239.11 KUM63119.1 - 0.0026 16.1 0.1 0.9 7.7 0.0 3.1 2 1 1 3 3 3 2 Cytochrome D1 heme domain Nbas_N PF15492.1 KUM63119.1 - 0.016 14.3 6.9 10 5.0 0.0 5.1 3 1 3 7 7 7 0 Neuroblastoma-amplified sequence, N terminal NACHT PF05729.7 KUM63119.1 - 0.035 13.7 0.1 0.11 12.1 0.1 1.8 1 0 0 1 1 1 0 NACHT domain Robl_LC7 PF03259.12 KUM63119.1 - 0.041 13.4 0.2 1.4 8.5 0.0 3.7 4 0 0 4 4 4 0 Roadblock/LC7 domain KAP_NTPase PF07693.9 KUM63119.1 - 0.064 12.2 0.6 0.13 11.2 0.4 1.4 1 0 0 1 1 1 0 KAP family P-loop domain Glyco_hydro_18 PF00704.23 KUM63120.1 - 3e-51 174.8 2.7 4.8e-50 170.9 1.9 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KUM63120.1 - 1.2e-05 25.1 20.2 2.4e-05 24.2 14.0 1.5 1 0 0 1 1 1 1 Chitin recognition protein NAD_binding_4 PF07993.7 KUM63121.1 - 2.5e-39 134.6 0.0 4.2e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KUM63121.1 - 2e-31 108.8 0.0 3.5e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KUM63121.1 - 4.4e-15 55.7 0.0 7.7e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family FAD_binding_4 PF01565.18 KUM63121.1 - 2.7e-09 36.6 3.0 8.6e-07 28.5 0.7 2.6 1 1 1 2 2 2 2 FAD binding domain BBE PF08031.7 KUM63121.1 - 2.7e-08 33.6 0.1 5.6e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like 3Beta_HSD PF01073.14 KUM63121.1 - 2.5e-05 23.1 0.0 5.3e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KUM63121.1 - 0.00052 20.0 0.0 0.0046 16.9 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KUM63121.1 - 0.0019 18.1 0.4 0.0071 16.2 0.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KUM63121.1 - 0.0062 15.4 0.1 0.071 11.9 0.0 2.4 2 0 0 2 2 2 1 RmlD substrate binding domain PP-binding PF00550.20 KUM63121.1 - 0.012 15.8 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 Phosphopantetheine attachment site KR PF08659.5 KUM63121.1 - 0.013 15.1 0.1 0.035 13.7 0.1 1.6 1 1 0 1 1 1 0 KR domain UvrC_HhH_N PF08459.6 KUM63121.1 - 0.033 13.7 0.0 0.076 12.5 0.0 1.5 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal NmrA PF05368.8 KUM63121.1 - 0.085 12.1 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family Mob1_phocein PF03637.12 KUM63122.1 - 1.3e-71 239.8 0.1 1.8e-71 239.4 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family OSCP PF00213.13 KUM63123.1 - 1.7e-40 138.6 3.2 2e-40 138.4 2.2 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF1674 PF07896.7 KUM63124.1 - 5.7e-16 58.4 4.2 9.9e-16 57.6 2.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Aminotran_3 PF00202.16 KUM63125.1 - 8.8e-98 327.2 0.0 1.1e-97 326.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KUM63125.1 - 0.00017 20.6 0.0 0.00034 19.6 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Diphthamide_syn PF01866.12 KUM63126.1 - 1.2e-113 379.3 0.0 1.6e-113 378.9 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein HMGL-like PF00682.14 KUM63127.1 - 1e-41 143.1 0.2 1.8e-41 142.4 0.1 1.4 1 1 0 1 1 1 1 HMGL-like CENP-I PF07778.6 KUM63128.1 - 0.001 17.3 0.7 0.0012 17.1 0.5 1.1 1 0 0 1 1 1 1 Mis6 Bromodomain PF00439.20 KUM63129.1 - 5.3e-17 61.5 0.0 1.2e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Glyco_hydro_63 PF03200.11 KUM63130.1 - 2.8e-06 25.5 6.2 6.6e-05 20.9 0.1 3.7 4 1 0 4 4 4 2 Mannosyl oligosaccharide glucosidase TelA PF05816.6 KUM63131.1 - 0.0017 17.1 2.1 0.0018 17.0 1.5 1.0 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) ADIP PF11559.3 KUM63131.1 - 0.0019 18.0 4.0 0.0024 17.7 2.8 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding LURAP PF14854.1 KUM63131.1 - 0.0036 17.0 1.0 0.0042 16.8 0.7 1.1 1 0 0 1 1 1 1 Leucine rich adaptor protein DUF2076 PF09849.4 KUM63131.1 - 0.016 15.2 9.2 0.021 14.8 6.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Mcm10 PF09332.6 KUM63131.1 - 0.022 14.1 4.6 0.022 14.1 3.2 1.0 1 0 0 1 1 1 0 Mcm10 replication factor DUF4407 PF14362.1 KUM63131.1 - 0.03 13.2 3.4 0.029 13.3 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OrfB_IS605 PF01385.14 KUM63131.1 - 0.049 13.0 0.2 0.06 12.7 0.2 1.1 1 0 0 1 1 1 0 Probable transposase DASH_Spc34 PF08657.5 KUM63131.1 - 0.18 11.4 4.6 0.32 10.6 3.3 1.4 1 1 0 1 1 1 0 DASH complex subunit Spc34 SlyX PF04102.7 KUM63131.1 - 1.2 9.5 7.4 1.8 8.9 5.1 1.6 1 1 0 1 1 1 0 SlyX SIN1 PF05422.7 KUM63132.1 - 7.4e-24 84.1 9.1 7.1e-14 51.2 5.4 2.9 2 1 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) RFC1 PF08519.7 KUM63133.1 - 3.8e-56 189.1 0.0 9.6e-56 187.8 0.0 1.7 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 KUM63133.1 - 7e-12 45.3 0.0 1.8e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 KUM63133.1 - 4.9e-10 39.7 0.1 1.2e-09 38.4 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KUM63133.1 - 4e-07 30.2 0.0 9.7e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KUM63133.1 - 3.3e-05 24.6 1.8 8.6e-05 23.3 0.0 2.7 2 0 0 2 2 1 1 AAA domain Rad17 PF03215.10 KUM63133.1 - 4.8e-05 22.2 0.0 0.0001 21.1 0.0 1.4 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 KUM63133.1 - 0.00069 19.3 0.1 0.0022 17.7 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KUM63133.1 - 0.0018 18.3 0.7 0.02 14.9 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 KUM63133.1 - 0.0021 17.9 0.0 0.005 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KUM63133.1 - 0.0028 16.7 0.1 0.0082 15.2 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KUM63133.1 - 0.004 17.0 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KUM63133.1 - 0.013 15.7 0.1 0.013 15.7 0.1 3.6 5 1 1 6 6 5 0 AAA domain NTPase_1 PF03266.10 KUM63133.1 - 0.034 13.8 1.0 0.53 9.9 0.1 2.6 1 1 1 2 2 2 0 NTPase AAA_5 PF07728.9 KUM63133.1 - 0.047 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 KUM63133.1 - 0.067 12.8 0.0 0.35 10.5 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 KUM63133.1 - 0.14 12.1 0.0 0.14 12.1 0.0 2.0 2 0 0 2 2 1 0 AAA domain Ribosomal_L16 PF00252.13 KUM63134.1 - 1.2e-28 99.5 0.2 1.5e-28 99.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Rep_fac_C PF08542.6 KUM63136.1 - 4.5e-21 74.6 0.0 1.1e-20 73.3 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KUM63136.1 - 1.7e-11 44.0 0.0 3.7e-11 42.9 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KUM63136.1 - 2.7e-06 27.5 0.1 6.4e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KUM63136.1 - 3.8e-05 23.8 0.8 0.00037 20.6 0.3 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KUM63136.1 - 0.00041 20.3 2.2 0.082 12.8 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 KUM63136.1 - 0.018 14.9 0.1 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 KUM63136.1 - 0.019 15.0 0.3 0.37 10.8 0.2 2.4 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_10 PF12846.2 KUM63136.1 - 0.029 13.8 0.1 0.86 8.9 0.0 2.1 1 1 0 2 2 2 0 AAA-like domain ABC_tran PF00005.22 KUM63136.1 - 0.031 14.5 0.1 0.068 13.4 0.0 1.6 1 1 0 1 1 1 0 ABC transporter SNF2_N PF00176.18 KUM63136.1 - 0.056 12.2 0.1 0.068 11.9 0.1 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Arch_ATPase PF01637.13 KUM63136.1 - 0.064 12.9 0.0 0.13 11.9 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase CtaG_Cox11 PF04442.9 KUM63137.1 - 2.4e-58 196.2 0.0 3.3e-58 195.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 HLH PF00010.21 KUM63139.1 - 4.7e-07 29.3 0.0 8.9e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Abhydrolase_3 PF07859.8 KUM63141.1 - 2.9e-33 115.2 0.1 2.6e-22 79.4 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KUM63141.1 - 0.19 10.2 0.0 0.32 9.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) CLN3 PF02487.12 KUM63142.1 - 3.5e-99 332.3 15.1 2e-97 326.5 10.5 2.4 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.11 KUM63142.1 - 0.0054 15.5 27.4 0.091 11.4 16.3 3.0 1 1 0 1 1 1 1 Major Facilitator Superfamily HAD_2 PF13419.1 KUM63143.1 - 1e-28 100.7 0.1 1.2e-28 100.4 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KUM63143.1 - 8e-06 26.4 0.0 0.00014 22.3 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 KUM63143.1 - 0.023 14.5 0.0 6.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HAD PF12710.2 KUM63143.1 - 0.035 14.2 0.0 0.041 14.0 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase AA_permease PF00324.16 KUM63144.1 - 1.1e-89 301.0 36.9 1.4e-89 300.6 25.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KUM63144.1 - 8.3e-27 93.7 39.4 1e-26 93.4 27.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF543 PF04418.7 KUM63144.1 - 0.12 12.2 3.0 5.3 7.0 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Oxidored_FMN PF00724.15 KUM63145.1 - 8.7e-44 149.8 0.0 1.5e-43 149.0 0.0 1.3 2 0 0 2 2 2 1 NADH:flavin oxidoreductase / NADH oxidase family DAO PF01266.19 KUM63146.1 - 9.9e-57 192.4 0.6 1.2e-56 192.2 0.4 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KUM63146.1 - 3.9e-05 23.8 0.7 0.0044 17.1 0.5 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM63146.1 - 0.00025 20.8 1.1 0.043 13.5 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 KUM63146.1 - 0.012 14.5 0.0 0.51 9.2 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KUM63146.1 - 0.032 14.2 0.3 0.092 12.7 0.2 1.9 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KUM63146.1 - 0.073 11.8 4.4 1.2 7.8 3.0 2.1 1 1 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KUM63146.1 - 0.12 10.8 0.5 0.71 8.2 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.9 KUM63146.1 - 0.48 10.2 3.5 11 5.8 2.4 2.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 KUM63148.1 - 2.6e-36 125.0 61.8 2e-26 92.5 22.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LPAM_2 PF13627.1 KUM63148.1 - 5.8 6.7 6.0 1.5 8.6 0.1 3.2 2 0 0 2 2 2 0 Prokaryotic lipoprotein-attachment site Fungal_trans PF04082.13 KUM63149.1 - 5.8e-25 87.6 0.9 5.8e-25 87.6 0.6 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF1275 PF06912.6 KUM63149.1 - 0.095 11.8 0.1 0.26 10.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1275) AAA_16 PF13191.1 KUM63150.1 - 0.00013 22.0 0.2 0.0013 18.7 0.1 2.1 1 1 1 2 2 2 1 AAA ATPase domain KTI12 PF08433.5 KUM63150.1 - 0.02 14.1 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.1 KUM63150.1 - 0.024 14.5 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KUM63150.1 - 0.045 14.5 0.1 0.16 12.8 0.0 1.9 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 KUM63150.1 - 0.047 13.3 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.4 KUM63150.1 - 0.053 12.4 0.1 0.41 9.5 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MobB PF03205.9 KUM63150.1 - 0.065 12.9 0.0 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 KUM63150.1 - 0.072 12.7 0.1 0.24 11.0 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Nbs1_C PF08599.5 KUM63150.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 AAA_30 PF13604.1 KUM63150.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KUM63150.1 - 0.14 12.3 0.2 1.9 8.6 0.1 2.3 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 KUM63150.1 - 0.19 10.9 0.0 0.35 10.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Rgp1 PF08737.5 KUM63151.1 - 4.3e-110 368.6 0.0 8.1e-110 367.7 0.0 1.5 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.24 KUM63151.1 - 0.003 17.3 0.0 0.0077 16.0 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Neugrin PF06413.6 KUM63152.1 - 2e-12 47.4 0.2 2e-12 47.4 0.1 2.1 1 1 1 2 2 2 1 Neugrin MRP-L20 PF12824.2 KUM63152.1 - 0.0015 18.4 12.8 0.0015 18.4 8.9 2.7 2 1 1 3 3 3 1 Mitochondrial ribosomal protein subunit L20 Acyl-CoA_dh_N PF02771.11 KUM63152.1 - 0.083 13.4 0.7 0.083 13.4 0.5 2.3 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain Sigma70_r3 PF04539.11 KUM63152.1 - 0.13 12.1 0.1 0.13 12.1 0.1 1.8 2 0 0 2 2 2 0 Sigma-70 region 3 DUF4390 PF14334.1 KUM63153.1 - 0.055 12.6 0.1 0.055 12.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4390) WD40 PF00400.27 KUM63154.1 - 1.1e-14 53.6 0.1 0.01 15.6 0.0 6.0 5 0 0 5 5 5 4 WD domain, G-beta repeat SPO22 PF08631.5 KUM63155.1 - 2e-19 69.7 0.0 5.4e-19 68.3 0.0 1.7 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.1 KUM63155.1 - 0.046 14.0 0.0 0.046 14.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat SnoaL_2 PF12680.2 KUM63156.1 - 0.15 12.5 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain CENP-Q PF13094.1 KUM63159.1 - 5.7e-48 162.9 4.9 5.7e-48 162.9 3.4 1.5 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF4407 PF14362.1 KUM63159.1 - 0.22 10.4 1.8 0.28 10.1 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SlyX PF04102.7 KUM63159.1 - 0.33 11.3 4.5 1.6 9.1 1.6 2.7 2 0 0 2 2 2 0 SlyX YMF19 PF02326.10 KUM63160.1 - 0.04 14.4 2.7 0.05 14.1 1.9 1.2 1 0 0 1 1 1 0 Plant ATP synthase F0 ETRAMP PF09716.5 KUM63160.1 - 0.054 13.4 1.2 0.076 12.9 0.8 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Plasmodium_Vir PF05795.6 KUM63160.1 - 0.076 12.1 1.9 0.085 12.0 1.4 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Carn_acyltransf PF00755.15 KUM63161.1 - 1.8e-179 597.6 0.0 2.1e-179 597.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Rxt3 PF08642.5 KUM63163.1 - 2.6e-28 98.5 0.0 5.2e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 KUM63163.1 - 0.0031 17.4 0.0 0.0072 16.2 0.0 1.6 1 0 0 1 1 1 1 LCCL domain Sulfatase PF00884.18 KUM63164.1 - 1.9e-18 66.7 0.4 3.1e-18 65.9 0.3 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KUM63164.1 - 1.7e-06 27.6 0.0 3.2e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KUM63164.1 - 7.4e-05 21.3 0.0 0.00012 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.13 KUM63164.1 - 0.028 13.7 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF1501 PF07394.7 KUM63164.1 - 0.091 11.5 0.0 0.19 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Cupin_3 PF05899.7 KUM63166.1 - 1.3e-07 30.8 0.3 2.2e-07 30.1 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.7 KUM63166.1 - 0.00016 21.2 0.0 0.00023 20.7 0.0 1.3 1 1 0 1 1 1 1 Ethanolamine utilisation protein EutQ DUF4437 PF14499.1 KUM63166.1 - 0.012 14.5 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) Cupin_2 PF07883.6 KUM63166.1 - 0.017 14.5 0.1 0.032 13.7 0.1 1.5 1 0 0 1 1 1 0 Cupin domain Skp1_POZ PF03931.10 KUM63168.1 - 3.5e-05 23.7 0.0 5.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain zf-C3HC4_3 PF13920.1 KUM63169.1 - 4.1e-08 32.7 12.3 7.3e-08 31.9 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Penicillinase_R PF03965.11 KUM63170.1 - 0.092 12.8 0.2 3.7 7.6 0.0 3.0 3 0 0 3 3 3 0 Penicillinase repressor Malic_M PF03949.10 KUM63171.1 - 2.5e-81 272.9 0.0 3.3e-81 272.5 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KUM63171.1 - 6.8e-66 221.3 0.0 1.1e-65 220.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF2419 PF10343.4 KUM63172.1 - 5.3e-96 321.2 0.0 5.9e-96 321.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) DUF1563 PF07599.6 KUM63172.1 - 0.0026 17.6 0.5 0.0048 16.7 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1563) DUF2419 PF10343.4 KUM63173.1 - 6.2e-28 97.8 0.1 9.2e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) DUF4121 PF13497.1 KUM63173.1 - 0.02 13.8 0.2 0.027 13.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) ThiF PF00899.16 KUM63174.1 - 6e-41 139.4 0.2 1.1e-40 138.5 0.1 1.5 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 KUM63174.1 - 1.5e-27 94.9 0.7 3.4e-27 93.7 0.5 1.7 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KUM63174.1 - 3.8e-20 71.0 2.6 8.8e-20 69.8 1.8 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 KUM63174.1 - 1.5e-17 63.5 0.3 4.9e-17 61.8 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 KUM63174.1 - 0.00054 20.1 0.2 0.004 17.3 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 KUM63174.1 - 0.0012 18.9 0.0 0.0034 17.4 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KUM63174.1 - 0.018 15.4 0.1 1.3 9.4 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Sec20 PF03908.8 KUM63174.1 - 0.055 13.1 1.4 0.58 9.8 0.2 2.7 2 0 0 2 2 2 0 Sec20 adh_short PF00106.20 KUM63175.1 - 3.2e-26 92.2 0.7 3e-24 85.8 0.5 2.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM63175.1 - 5.1e-13 49.3 0.0 9e-13 48.5 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM63175.1 - 1.2e-11 44.6 0.5 7.1e-11 42.0 0.3 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM63175.1 - 2.6e-06 27.0 0.2 0.00019 20.9 0.1 2.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KUM63175.1 - 0.00022 20.2 0.1 0.0055 15.6 0.1 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KUM63175.1 - 0.0015 18.6 0.1 0.047 13.7 0.0 2.3 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 KUM63175.1 - 0.0015 18.9 0.0 0.0035 17.7 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 KUM63175.1 - 0.0018 18.3 0.4 0.06 13.3 0.1 2.2 1 1 1 2 2 2 1 NADH(P)-binding ABC_tran PF00005.22 KUM63176.1 - 7.7e-33 113.6 0.0 1.6e-32 112.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KUM63176.1 - 1.4e-28 100.0 13.1 2.6e-28 99.2 9.1 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 KUM63176.1 - 1.1e-07 31.3 0.0 1.2e-06 27.9 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KUM63176.1 - 1.2e-05 25.4 0.6 0.0067 16.4 0.1 3.2 3 1 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 KUM63176.1 - 0.0024 17.7 0.2 0.038 13.8 0.1 2.8 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KUM63176.1 - 0.0066 15.9 0.2 0.017 14.6 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KUM63176.1 - 0.012 15.6 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 KUM63176.1 - 0.027 13.8 0.0 0.24 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KUM63176.1 - 0.068 12.3 0.0 0.16 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 KUM63176.1 - 0.11 12.2 0.1 1.1 8.9 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KUM63176.1 - 0.2 11.8 0.7 2.2 8.4 0.5 2.2 1 1 0 1 1 1 0 AAA domain zf-ZPR1 PF03367.8 KUM63177.1 - 1.9e-90 300.2 0.0 7.8e-46 155.1 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.14 KUM63177.1 - 0.02 14.5 0.7 0.47 10.1 0.1 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family FeS PF04060.8 KUM63177.1 - 0.026 14.1 0.9 0.061 12.8 0.6 1.6 1 0 0 1 1 1 0 Putative Fe-S cluster Cytochrome_C554 PF13435.1 KUM63177.1 - 0.03 14.3 0.2 0.16 12.0 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c554 and c-prime Elf1 PF05129.8 KUM63177.1 - 0.044 13.4 1.3 1.8 8.3 0.1 2.7 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like E7 PF00527.13 KUM63177.1 - 0.77 9.9 4.3 0.86 9.7 0.1 3.1 4 0 0 4 4 4 0 E7 protein, Early protein Cytochrome_C7 PF14522.1 KUM63177.1 - 1.2 8.7 5.8 6.5 6.4 1.5 2.9 2 1 1 3 3 3 0 Cytochrome c7 Pro_isomerase PF00160.16 KUM63178.1 - 3.6e-36 124.7 0.0 4.5e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Glycos_transf_1 PF00534.15 KUM63179.1 - 2.4e-12 46.6 0.0 5.3e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KUM63179.1 - 3.6e-08 33.6 0.0 8.4e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 APH PF01636.18 KUM63179.1 - 4.4e-06 26.6 0.5 7e-05 22.6 0.1 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family TIP120 PF08623.5 KUM63180.1 - 1.1e-61 207.2 0.2 1.3e-60 203.8 0.0 2.6 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT PF02985.17 KUM63180.1 - 9.4e-09 34.6 4.7 0.13 12.4 0.0 8.5 8 0 0 8 8 8 2 HEAT repeat Arm PF00514.18 KUM63180.1 - 0.014 15.1 0.0 2.4 8.1 0.0 4.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DUF1546 PF07571.8 KUM63180.1 - 0.089 12.9 0.0 4 7.6 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1546) HEAT_EZ PF13513.1 KUM63180.1 - 0.2 12.1 23.9 1.2 9.7 0.0 8.9 10 3 2 12 12 12 0 HEAT-like repeat HEAT_PBS PF03130.11 KUM63180.1 - 0.57 10.8 3.8 4 8.1 0.3 4.2 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Methyltransf_23 PF13489.1 KUM63181.1 - 3.3e-08 33.4 0.0 4.5e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM63181.1 - 0.00016 22.1 0.0 0.0014 19.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KUM63181.1 - 0.0016 17.5 0.0 0.003 16.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 KUM63181.1 - 0.036 13.6 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF2435 PF10363.4 KUM63182.1 - 5.3e-25 87.1 0.0 7.7e-24 83.4 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 KUM63182.1 - 2.9e-06 26.6 0.0 1.1e-05 24.7 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) DBR1 PF05011.8 KUM63183.1 - 1.8e-41 141.4 1.8 2.3e-41 141.0 0.0 2.1 4 0 0 4 4 4 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 KUM63183.1 - 2.7e-08 33.4 0.5 5.1e-08 32.5 0.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ORC6 PF05460.8 KUM63184.1 - 3e-28 98.9 0.0 3.6e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) DUF4259 PF14078.1 KUM63184.1 - 0.054 13.9 0.1 0.054 13.9 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) ORC6 PF05460.8 KUM63185.1 - 4.5e-20 72.0 0.6 5.2e-20 71.8 0.4 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) CFEM PF05730.6 KUM63186.1 - 2.1e-15 56.2 10.2 4.1e-15 55.3 7.0 1.5 1 0 0 1 1 1 1 CFEM domain PAP1 PF08601.5 KUM63186.1 - 1.7 8.2 14.7 2.1 7.9 10.2 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DUF566 PF04484.7 KUM63186.1 - 8.8 5.7 13.1 10 5.5 9.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Erf4 PF10256.4 KUM63187.1 - 0.044 13.6 0.1 0.084 12.7 0.1 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Arrestin_C PF02752.17 KUM63188.1 - 2.1e-15 57.0 0.2 1.4e-14 54.3 0.0 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain CZB PF13682.1 KUM63189.1 - 0.03 14.4 0.0 0.045 13.9 0.0 1.2 1 0 0 1 1 1 0 Chemoreceptor zinc-binding domain DNA_pol_delta_4 PF04081.8 KUM63190.1 - 4.5e-25 88.3 0.6 6.3e-25 87.8 0.4 1.1 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Med13_C PF06333.7 KUM63190.1 - 0.11 11.0 1.4 0.13 10.7 1.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal ThiF PF00899.16 KUM63191.1 - 1.5e-09 37.7 0.0 3.8e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 ThiF family tRNA_int_end_N2 PF12928.2 KUM63192.1 - 7.3e-36 121.4 0.0 1.4e-35 120.5 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 KUM63192.1 - 0.0023 17.4 0.0 0.0044 16.5 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Melibiase PF02065.13 KUM63193.1 - 4.8e-161 535.8 0.0 5.9e-161 535.5 0.0 1.1 1 0 0 1 1 1 1 Melibiase DUF187 PF02638.10 KUM63193.1 - 8.3e-07 28.1 0.0 1.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 SMN PF06003.7 KUM63194.1 - 6.2e-08 32.0 3.7 3.5e-05 23.0 0.9 2.1 2 0 0 2 2 2 2 Survival motor neuron protein (SMN) RRM_1 PF00076.17 KUM63195.1 - 1.2e-13 50.4 0.0 3.4e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM63195.1 - 6.8e-10 38.7 0.0 1.2e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM63195.1 - 5.8e-08 32.4 0.1 1.4e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KUM63195.1 - 0.088 12.5 0.2 0.6 9.9 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif PT PF04886.7 KUM63196.1 - 1.4 8.3 15.7 4.9 6.5 10.9 2.0 1 1 0 1 1 1 0 PT repeat Thiolase_C PF02803.13 KUM63197.1 - 1.1e-12 47.5 0.7 3.4e-11 42.6 0.5 2.5 1 1 1 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KUM63197.1 - 2.6e-07 30.1 0.0 1.8e-05 24.2 0.0 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 KUM63197.1 - 1.6e-05 24.0 0.5 5.1e-05 22.3 0.0 2.1 2 1 0 3 3 3 1 Thiolase, N-terminal domain SpoVAD PF07451.6 KUM63197.1 - 0.0064 14.9 0.2 0.034 12.6 0.1 2.0 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) ketoacyl-synt PF00109.21 KUM63197.1 - 0.02 14.4 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain CHD5 PF04420.9 KUM63198.1 - 1.8e-61 206.4 2.8 2.4e-61 206.0 1.9 1.2 1 0 0 1 1 1 1 CHD5-like protein DUF4234 PF14018.1 KUM63200.1 - 0.033 13.9 1.0 0.04 13.6 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) DUF1029 PF06269.7 KUM63200.1 - 0.2 11.6 2.0 0.22 11.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1029) DUF3431 PF11913.3 KUM63201.1 - 1.7e-72 243.5 0.0 2.1e-72 243.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) PPTA PF01239.17 KUM63203.1 - 1.6e-05 24.0 3.5 0.13 11.6 0.7 3.6 3 0 0 3 3 3 3 Protein prenyltransferase alpha subunit repeat Rad10 PF03834.9 KUM63204.1 - 8.5e-32 108.6 0.0 1.4e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 KUM63204.1 - 3.4e-05 23.9 0.0 6.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.18 KUM63204.1 - 0.00023 20.6 0.0 0.00056 19.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.2 KUM63204.1 - 0.0066 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif RsbRD_N PF14361.1 KUM63204.1 - 0.83 10.1 3.5 0.64 10.5 0.8 1.9 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain p450 PF00067.17 KUM63205.1 - 2.6e-59 200.9 0.0 3.4e-59 200.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Metal_resist PF13801.1 KUM63207.1 - 0.31 11.0 2.4 0.47 10.4 0.2 2.5 2 0 0 2 2 2 0 Heavy-metal resistance ADH_zinc_N PF00107.21 KUM63208.1 - 1.2e-10 41.0 0.0 2.2e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM63208.1 - 1.3e-07 31.3 0.0 2.4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AMP-binding PF00501.23 KUM63209.1 - 2.5e-75 253.4 0.0 4.3e-75 252.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 KUM63209.1 - 4.4e-71 239.3 0.0 1.2e-70 237.9 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.15 KUM63209.1 - 3.8e-47 160.5 0.0 7.7e-47 159.5 0.0 1.4 1 0 0 1 1 1 1 Condensation domain Acyl_transf_1 PF00698.16 KUM63209.1 - 2.9e-45 154.9 0.1 5.8e-45 153.9 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KUM63209.1 - 6.4e-44 149.7 0.0 4.9e-42 143.6 0.0 2.8 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 KUM63209.1 - 4.4e-43 147.5 0.0 9.4e-43 146.4 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KUM63209.1 - 2.5e-38 131.6 0.0 6.4e-34 117.2 0.0 3.1 2 0 0 2 2 2 2 short chain dehydrogenase NAD_binding_4 PF07993.7 KUM63209.1 - 4.7e-32 110.8 0.0 1.7e-31 109.0 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 KUM63209.1 - 6e-31 106.7 0.0 1.8e-30 105.2 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KUM63209.1 - 1.3e-16 60.6 3.7 2.6e-09 37.1 0.0 3.3 3 0 0 3 3 2 2 Phosphopantetheine attachment site Epimerase PF01370.16 KUM63209.1 - 5.9e-09 35.7 0.0 1.3e-06 28.0 0.0 2.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family HxxPF_rpt PF13745.1 KUM63209.1 - 7.4e-09 35.8 0.1 2.1e-08 34.3 0.1 1.9 1 0 0 1 1 1 1 HxxPF-repeated domain Methyltransf_23 PF13489.1 KUM63209.1 - 7.1e-08 32.3 0.0 2.5e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM63209.1 - 7.1e-08 32.8 0.1 4.4e-07 30.2 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM63209.1 - 1.9e-06 28.2 0.1 1e-05 25.8 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain Thiolase_N PF00108.18 KUM63209.1 - 5.4e-06 25.5 0.1 1.3e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.14 KUM63209.1 - 1.8e-05 23.5 0.0 3.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_31 PF13847.1 KUM63209.1 - 0.014 14.9 0.0 0.062 12.8 0.0 2.0 2 0 0 2 2 1 0 Methyltransferase domain DUF3156 PF11354.3 KUM63209.1 - 0.045 13.1 0.1 0.16 11.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3156) CPDase PF07823.6 KUM63209.1 - 0.095 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein Ubie_methyltran PF01209.13 KUM63209.1 - 0.3 10.1 0.0 0.69 8.9 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TRAM_LAG1_CLN8 PF03798.11 KUM63211.1 - 1.4e-39 135.7 20.0 1.4e-39 135.7 13.9 1.5 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KUM63211.1 - 1.6e-18 65.9 0.0 3.8e-18 64.7 0.0 1.7 1 0 0 1 1 1 1 TRAM1-like protein RasGEF PF00617.14 KUM63213.1 - 2.3e-59 200.3 0.0 3.8e-59 199.5 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KUM63213.1 - 8.1e-23 80.5 0.6 1.5e-22 79.6 0.1 1.7 2 0 0 2 2 2 1 RasGEF N-terminal motif MFS_1 PF07690.11 KUM63214.1 - 7.8e-17 61.0 34.6 5.6e-16 58.2 23.7 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM63214.1 - 5.3e-07 28.2 7.2 5.3e-07 28.2 5.0 1.7 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) SnoaL_2 PF12680.2 KUM63215.1 - 0.0035 17.7 0.0 0.0048 17.2 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain K1 PF02960.9 KUM63216.1 - 0.012 15.6 2.3 0.027 14.5 1.6 1.6 1 0 0 1 1 1 0 K1 glycoprotein DUF2371 PF10177.4 KUM63216.1 - 0.018 14.9 0.4 0.66 9.8 0.0 2.9 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2371) IncA PF04156.9 KUM63216.1 - 0.15 11.6 1.5 4.7 6.7 2.4 2.4 2 0 0 2 2 2 0 IncA protein FAM176 PF14851.1 KUM63216.1 - 0.45 10.1 0.0 0.45 10.1 0.0 1.9 2 0 0 2 2 2 0 FAM176 family AMP-binding PF00501.23 KUM63217.1 - 2.4e-85 286.4 0.0 3.4e-85 285.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KUM63217.1 - 4.1e-31 107.9 0.1 2.1e-20 72.7 0.0 2.9 2 1 0 2 2 2 2 Condensation domain HxxPF_rpt PF13745.1 KUM63217.1 - 2.1e-13 50.3 0.0 7.3e-13 48.6 0.0 2.1 1 0 0 1 1 1 1 HxxPF-repeated domain PP-binding PF00550.20 KUM63217.1 - 5.4e-12 45.7 0.0 1.5e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KUM63217.1 - 1.5e-06 29.0 1.0 3.2e-05 24.7 0.7 3.0 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans_2 PF11951.3 KUM63218.1 - 3.7e-09 35.6 0.5 2.2e-08 33.1 0.1 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM63218.1 - 4.6e-06 26.4 15.0 4.6e-06 26.4 10.4 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EBP PF05241.7 KUM63219.1 - 0.0076 15.2 0.8 0.0095 14.9 0.6 1.1 1 0 0 1 1 1 1 Emopamil binding protein BRO1 PF03097.13 KUM63220.1 - 1.6e-115 385.8 0.0 2.9e-115 385.0 0.0 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KUM63220.1 - 1.4e-83 280.3 4.2 2.5e-83 279.4 2.9 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Mito_carr PF00153.22 KUM63221.1 - 5.6e-46 154.1 1.7 1.2e-17 63.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TRAM_LAG1_CLN8 PF03798.11 KUM63222.1 - 2.1e-32 112.3 20.2 4.1e-32 111.3 14.0 1.5 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 KUM63222.1 - 1e-21 76.1 0.2 2.8e-21 74.7 0.0 1.8 2 0 0 2 2 2 1 TRAM1-like protein Septin PF00735.13 KUM63223.1 - 5.6e-115 383.1 0.3 5.6e-115 383.1 0.2 1.3 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KUM63223.1 - 3.1e-07 30.3 0.0 5.9e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KUM63223.1 - 1.1e-06 28.2 0.1 2e-05 24.0 0.2 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KUM63223.1 - 1e-05 24.7 0.0 2.6e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KUM63223.1 - 0.00092 19.3 0.1 0.0039 17.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 KUM63223.1 - 0.0034 16.9 0.0 0.0061 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 KUM63223.1 - 0.0058 17.1 0.8 0.017 15.6 0.0 2.2 2 1 0 3 3 2 1 Miro-like protein AIG1 PF04548.11 KUM63223.1 - 0.0065 15.5 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 AIG1 family FtsK_SpoIIIE PF01580.13 KUM63223.1 - 0.0076 15.7 0.1 0.019 14.4 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family IIGP PF05049.8 KUM63223.1 - 0.0089 14.8 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Pox_A32 PF04665.7 KUM63223.1 - 0.014 14.7 0.1 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Ras PF00071.17 KUM63223.1 - 0.034 13.5 0.5 0.11 11.8 0.3 1.9 2 1 0 2 2 2 0 Ras family ABC_tran PF00005.22 KUM63223.1 - 0.038 14.2 0.1 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.7 KUM63223.1 - 0.042 13.5 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Dynamin_N PF00350.18 KUM63223.1 - 0.056 13.2 5.8 1 9.1 0.0 3.0 2 1 1 3 3 3 0 Dynamin family T2SE PF00437.15 KUM63223.1 - 0.057 12.3 0.4 0.14 11.0 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein PduV-EutP PF10662.4 KUM63223.1 - 0.06 12.8 0.3 2.9 7.3 0.2 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 KUM63223.1 - 0.062 12.9 0.1 0.062 12.9 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase Sigma54_activat PF00158.21 KUM63223.1 - 0.077 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.1 KUM63223.1 - 0.078 12.9 0.4 0.39 10.6 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain KAP_NTPase PF07693.9 KUM63223.1 - 0.089 11.7 1.5 0.17 10.8 1.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain ATP_bind_1 PF03029.12 KUM63223.1 - 0.13 11.7 0.9 8.8 5.7 0.1 2.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 KUM63223.1 - 0.14 12.3 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Myc-LZ PF02344.10 KUM63223.1 - 0.58 9.8 5.1 0.95 9.1 0.3 2.6 2 0 0 2 2 2 0 Myc leucine zipper domain AAA_23 PF13476.1 KUM63223.1 - 9.3 6.5 17.0 3e+02 1.6 11.8 2.1 1 1 0 1 1 1 0 AAA domain WD40 PF00400.27 KUM63224.1 - 1.7e-18 65.6 1.5 5e-07 29.3 0.4 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat FLgD_tudor PF13861.1 KUM63224.1 - 0.049 13.6 0.1 5.7 7.0 0.0 2.3 2 0 0 2 2 2 0 FlgD Tudor-like domain Asparaginase PF00710.15 KUM63225.1 - 3.8e-99 331.5 0.2 2.4e-89 299.3 0.0 2.1 2 0 0 2 2 2 2 Asparaginase Ank_2 PF12796.2 KUM63225.1 - 3.3e-11 43.3 0.1 6.4e-11 42.4 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KUM63225.1 - 3e-09 36.2 0.8 3.9e-06 26.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 KUM63225.1 - 8.3e-09 35.7 0.3 7.4e-05 23.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM63225.1 - 1.7e-07 31.2 0.0 5.5e-07 29.6 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM63225.1 - 0.00012 21.9 0.5 0.018 15.2 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Porphobil_deam PF01379.15 KUM63226.1 - 2.4e-61 206.3 0.0 3e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 KUM63226.1 - 1.7e-13 50.4 0.0 3.3e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain DOPA_dioxygen PF08883.6 KUM63227.1 - 4.1e-29 100.7 0.1 5.4e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Glyoxalase PF00903.20 KUM63228.1 - 1.1e-18 67.4 0.2 8.1e-13 48.4 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KUM63228.1 - 6.5e-12 45.4 0.1 5.2e-05 23.2 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KUM63228.1 - 3.4e-09 37.2 0.1 0.0028 18.2 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 KUM63228.1 - 3e-07 30.4 0.0 7.8e-06 25.8 0.0 2.7 3 0 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.1 KUM63228.1 - 0.00025 21.0 0.1 0.96 9.3 0.1 2.9 2 2 0 2 2 2 2 Glyoxalase-like domain Aminotran_1_2 PF00155.16 KUM63229.1 - 2.4e-13 49.7 0.0 3.2e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KUM63229.1 - 0.00019 20.1 0.0 0.0004 19.0 0.0 1.5 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Fungal_trans PF04082.13 KUM63230.1 - 3.9e-06 25.9 0.1 1.3e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF2360 PF10152.4 KUM63230.1 - 0.0097 16.2 1.5 0.031 14.5 1.0 1.8 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) GTPase_Cys_C PF12631.2 KUM63230.1 - 0.12 12.7 1.2 2.2 8.7 0.0 3.2 3 0 0 3 3 3 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Ndc1_Nup PF09531.5 KUM63230.1 - 1.4 7.2 6.1 2.5 6.4 4.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LCCL PF03815.14 KUM63231.1 - 7.9e-24 83.4 0.1 1.2e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 LCCL domain MFS_1 PF07690.11 KUM63232.1 - 2.3e-47 161.4 56.0 4.5e-42 144.0 29.3 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.4 KUM63232.1 - 0.011 15.6 2.5 0.2 11.6 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) FMN_dh PF01070.13 KUM63233.1 - 7.5e-109 363.8 0.0 9.7e-109 363.4 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KUM63233.1 - 6.4e-20 70.7 0.0 1.4e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NMO PF03060.10 KUM63233.1 - 9.7e-06 24.9 0.1 1.7e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KUM63233.1 - 0.0012 17.8 0.7 0.0094 14.8 0.1 2.2 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KUM63233.1 - 0.0019 17.1 0.0 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 KUM63233.1 - 0.039 13.0 0.1 0.77 8.7 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DUF1100 PF06500.6 KUM63234.1 - 7.8e-11 41.1 0.0 9.3e-11 40.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_5 PF12695.2 KUM63234.1 - 2.3e-10 40.3 0.0 5.5e-10 39.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KUM63234.1 - 1.4e-09 38.1 0.4 3.6e-09 36.8 0.1 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KUM63234.1 - 1.1e-05 25.0 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 KUM63234.1 - 2.6e-05 23.5 0.0 6.7e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 KUM63234.1 - 0.00054 19.7 0.0 0.0008 19.1 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.15 KUM63234.1 - 0.0026 17.2 0.0 0.012 15.0 0.0 1.8 1 1 0 1 1 1 1 Putative esterase TPR_10 PF13374.1 KUM63234.1 - 3.4 7.7 5.8 1.1 9.2 2.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat adh_short PF00106.20 KUM63235.1 - 2.3e-35 121.9 3.2 2.9e-35 121.6 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM63235.1 - 2.5e-31 109.2 0.0 3.1e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM63235.1 - 5.8e-19 68.4 1.8 8.2e-19 67.9 1.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM63235.1 - 0.00053 19.4 0.2 0.00064 19.2 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 KUM63235.1 - 0.0071 15.4 0.1 0.39 9.7 0.0 2.2 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CABS1 PF15367.1 KUM63235.1 - 0.037 12.9 0.0 0.049 12.5 0.0 1.1 1 0 0 1 1 1 0 Calcium-binding and spermatid-specific protein 1 NAD_binding_10 PF13460.1 KUM63235.1 - 0.17 11.8 2.1 0.31 11.0 1.5 1.6 1 1 0 1 1 1 0 NADH(P)-binding NmrA PF05368.8 KUM63235.1 - 0.19 10.9 1.7 0.39 9.9 1.2 1.5 1 0 0 1 1 1 0 NmrA-like family Cu-oxidase_3 PF07732.10 KUM63237.1 - 2.4e-41 140.1 1.0 2.4e-41 140.1 0.7 3.5 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KUM63237.1 - 1.3e-39 134.8 16.9 1.5e-37 128.1 3.2 4.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KUM63237.1 - 1.9e-34 118.8 3.5 1.6e-33 115.9 0.0 3.2 4 0 0 4 4 4 1 Multicopper oxidase ACT_7 PF13840.1 KUM63238.1 - 1.1e-24 85.7 0.4 9.4e-17 60.2 0.0 3.4 3 0 0 3 3 3 3 ACT domain Scytalone_dh PF02982.9 KUM63239.1 - 4e-79 263.7 3.5 4.9e-79 263.4 2.4 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 KUM63239.1 - 6.8e-08 32.4 1.8 8.2e-08 32.2 1.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain Transposase_24 PF03004.9 KUM63240.1 - 0.087 12.7 0.1 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) Nyv1_N PF09426.5 KUM63241.1 - 0.0059 16.1 2.5 0.0069 15.9 1.7 1.2 1 0 0 1 1 1 1 Vacuolar R-SNARE Nyv1 N terminal Turandot PF07240.6 KUM63241.1 - 0.89 9.0 6.3 17 5.0 3.0 2.9 2 1 0 2 2 2 0 Stress-inducible humoral factor Turandot Membr_traf_MHD PF10540.4 KUM63241.1 - 2.3 8.0 6.1 3.2 7.5 4.2 1.2 1 0 0 1 1 1 0 Munc13 (mammalian uncoordinated) homology domain FAD_binding_3 PF01494.14 KUM63243.1 - 3.8e-66 223.5 0.0 5.2e-66 223.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KUM63243.1 - 5.7e-31 107.3 0.0 9.4e-31 106.6 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain ThiF PF00899.16 KUM63243.1 - 0.026 14.3 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 ThiF family Pyr_redox PF00070.22 KUM63243.1 - 0.045 14.1 0.0 0.17 12.3 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KUM63243.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DUF4534 PF15049.1 KUM63244.1 - 0.036 13.7 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4534) WD40 PF00400.27 KUM63245.1 - 1.7e-08 34.0 3.6 0.034 14.0 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ PF01011.16 KUM63245.1 - 2.6e-05 23.5 0.4 0.25 10.9 0.0 2.6 2 0 0 2 2 2 2 PQQ enzyme repeat VID27 PF08553.5 KUM63245.1 - 0.003 15.8 0.0 0.004 15.4 0.0 1.2 1 0 0 1 1 1 1 VID27 cytoplasmic protein WI12 PF07107.6 KUM63245.1 - 0.13 12.1 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Wound-induced protein WI12 Fungal_trans PF04082.13 KUM63246.1 - 4e-10 39.0 0.2 2.1e-09 36.6 0.0 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain Syntaxin-6_N PF09177.6 KUM63248.1 - 3.6e-24 84.9 1.3 1.3e-23 83.2 0.1 2.2 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 KUM63248.1 - 1.8e-14 53.1 14.2 3.3e-14 52.3 2.3 3.1 3 0 0 3 3 3 1 SNARE domain AAA_13 PF13166.1 KUM63248.1 - 0.017 13.5 0.1 0.021 13.2 0.0 1.0 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.7 KUM63248.1 - 0.11 12.3 1.9 1.1 9.1 0.6 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 KUM63248.1 - 0.11 11.6 0.8 1.2 8.1 0.1 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein TBPIP PF07106.8 KUM63248.1 - 0.12 11.8 5.4 0.072 12.6 1.1 2.2 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF883 PF05957.8 KUM63248.1 - 0.14 12.5 3.3 3.7 8.0 0.0 3.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) NPV_P10 PF05531.7 KUM63248.1 - 0.16 12.2 6.0 14 6.0 0.1 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.17 KUM63248.1 - 0.17 11.9 2.1 0.48 10.4 0.4 2.3 2 2 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PilJ PF13675.1 KUM63248.1 - 0.22 11.8 5.2 0.6 10.4 0.7 2.7 1 1 2 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term LXG PF04740.7 KUM63248.1 - 0.25 11.1 3.6 0.34 10.6 0.3 2.2 2 0 0 2 2 2 0 LXG domain of WXG superfamily DUF4047 PF13256.1 KUM63248.1 - 0.27 11.1 1.7 0.32 10.9 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) CCDC144C PF14915.1 KUM63248.1 - 0.4 9.5 5.5 0.32 9.8 0.6 2.1 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region DUF972 PF06156.8 KUM63248.1 - 0.49 10.7 4.7 0.7 10.2 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) TMF_DNA_bd PF12329.3 KUM63248.1 - 1.5 8.6 6.4 0.81 9.5 0.3 2.9 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Adaptin_binding PF10199.4 KUM63248.1 - 1.6 8.9 7.5 3.1 8.0 5.2 1.5 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DASH_Dad2 PF08654.5 KUM63248.1 - 4.5 7.3 5.8 48 4.0 0.1 3.2 3 0 0 3 3 3 0 DASH complex subunit Dad2 APG6 PF04111.7 KUM63248.1 - 7.4 5.5 6.6 1.6 7.6 1.5 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 NmrA PF05368.8 KUM63250.1 - 2.5e-66 223.2 0.0 3e-66 223.0 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KUM63250.1 - 0.00044 20.3 0.0 0.00064 19.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAP PF00956.13 KUM63251.1 - 4e-46 157.1 1.8 6.9e-46 156.3 1.2 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Bd3614_N PF14442.1 KUM63251.1 - 0.91 9.4 9.0 2.7 7.9 3.3 2.4 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal NAAA-beta PF15508.1 KUM63252.1 - 1.5e-22 79.7 0.0 2.8e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Fungal_trans PF04082.13 KUM63253.1 - 5.4e-17 61.5 1.2 1.4e-16 60.1 0.7 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM63253.1 - 2e-05 24.3 10.9 3.6e-05 23.5 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L4 PF00573.17 KUM63254.1 - 4.6e-43 146.8 0.7 6.7e-43 146.3 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 KUM63254.1 - 2.1e-30 104.4 1.5 2.1e-30 104.4 1.0 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Glyco_hydro_61 PF03443.9 KUM63255.1 - 0.011 15.5 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 Serglycin PF04360.7 KUM63255.1 - 1.3 8.7 15.9 0.62 9.7 2.6 2.6 2 0 0 2 2 2 0 Serglycin DUF605 PF04652.11 KUM63255.1 - 2.3 7.5 10.6 3 7.1 7.3 1.1 1 0 0 1 1 1 0 Vta1 like SKIP_SNW PF02731.10 KUM63257.1 - 1.3e-67 226.1 3.7 1.3e-67 226.1 2.6 2.4 2 0 0 2 2 2 1 SKIP/SNW domain Nucleo_P87 PF07267.6 KUM63257.1 - 0.7 8.5 6.6 1.2 7.6 4.6 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF3395 PF11875.3 KUM63258.1 - 1.9e-26 92.5 0.1 3.3e-26 91.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 KUM63258.1 - 1.1e-16 60.2 0.2 2.6e-16 59.1 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain HNH_2 PF13391.1 KUM63259.1 - 2.2e-07 30.5 0.1 3.7e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 HNH endonuclease UPF0029 PF01205.14 KUM63260.1 - 1.1e-30 105.5 0.0 1.8e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 KUM63260.1 - 1.5e-08 34.4 0.0 2.6e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain adh_short PF00106.20 KUM63261.1 - 7.2e-09 35.7 0.1 1.2e-08 35.0 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KUM63261.1 - 1.7e-06 28.1 0.7 1.7e-06 28.1 0.5 1.6 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 KUM63261.1 - 3.5e-06 26.4 1.9 6.7e-06 25.5 1.3 1.5 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KUM63261.1 - 0.00053 19.5 0.1 0.0008 18.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KUM63261.1 - 0.0008 19.1 0.1 0.0025 17.5 0.0 1.7 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KUM63261.1 - 0.0011 18.7 0.1 0.0022 17.8 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Saccharop_dh PF03435.13 KUM63261.1 - 0.0017 17.4 0.9 0.07 12.0 0.5 2.2 1 1 1 2 2 2 1 Saccharopine dehydrogenase Eno-Rase_NADH_b PF12242.3 KUM63261.1 - 0.0021 17.7 0.3 0.0051 16.5 0.2 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Semialdhyde_dh PF01118.19 KUM63261.1 - 0.0043 17.3 0.2 0.025 14.8 0.1 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DUF1776 PF08643.5 KUM63261.1 - 0.027 13.6 0.0 0.054 12.6 0.0 1.6 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) DapB_N PF01113.15 KUM63261.1 - 0.027 14.3 1.4 0.074 12.9 0.5 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.15 KUM63261.1 - 0.054 13.6 0.3 0.14 12.2 0.2 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.7 KUM63261.1 - 0.068 12.0 0.2 0.26 10.1 0.0 1.8 1 1 1 2 2 2 0 Male sterility protein KIF1B PF12423.3 KUM63262.1 - 0.024 14.6 1.1 22 5.1 0.0 3.8 4 0 0 4 4 4 0 Kinesin protein 1B E1-E2_ATPase PF00122.15 KUM63263.1 - 6.7e-52 175.8 0.1 3.2e-51 173.6 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.21 KUM63263.1 - 4.5e-44 148.4 1.9 1e-12 47.9 0.0 5.3 5 0 0 5 5 5 4 Heavy-metal-associated domain Hydrolase PF00702.21 KUM63263.1 - 7e-39 134.4 0.1 1.3e-38 133.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KUM63263.1 - 1.5e-18 67.6 0.0 2.9e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KUM63263.1 - 4.1e-07 29.8 0.2 0.00096 18.7 0.1 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase ERCC4 PF02732.10 KUM63264.1 - 2.6e-30 105.0 0.0 4.7e-30 104.2 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain Epimerase PF01370.16 KUM63266.1 - 2.2e-20 73.1 0.0 2.9e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KUM63266.1 - 5.7e-12 44.9 0.0 7.1e-12 44.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KUM63266.1 - 4.5e-08 33.2 0.0 3.9e-06 26.8 0.0 2.3 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KUM63266.1 - 4.8e-08 32.2 0.0 0.00085 18.3 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 KUM63266.1 - 1.5e-07 31.5 0.0 2.1e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KUM63266.1 - 1.4e-06 27.4 0.0 7.7e-06 25.0 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 KUM63266.1 - 0.00011 21.9 0.0 0.062 12.9 0.0 2.4 1 1 0 2 2 2 2 KR domain Ldh_1_N PF00056.18 KUM63266.1 - 0.0042 16.9 0.0 0.0069 16.2 0.0 1.4 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KUM63266.1 - 0.016 14.1 0.0 0.14 11.0 0.0 2.1 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein EIN3 PF04873.8 KUM63267.1 - 1.1 8.4 7.6 1.3 8.1 5.3 1.2 1 0 0 1 1 1 0 Ethylene insensitive 3 Herpes_DNAp_acc PF04929.7 KUM63267.1 - 2.7 6.8 9.3 3.9 6.3 6.5 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor ChAPs PF09295.5 KUM63268.1 - 1e-157 524.9 0.0 1.3e-157 524.6 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 KUM63268.1 - 1.8e-06 27.5 0.1 0.017 14.7 0.0 2.6 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KUM63268.1 - 0.00024 20.5 0.1 4 7.1 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KUM63268.1 - 0.00043 19.9 0.6 0.47 10.4 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KUM63268.1 - 0.00092 18.8 0.0 6.5 6.7 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KUM63268.1 - 0.0018 18.1 0.6 9.8 6.1 0.0 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 KUM63268.1 - 0.0023 17.0 1.1 0.18 10.8 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KUM63268.1 - 0.0024 18.3 4.5 2.1 9.2 0.0 4.7 3 2 3 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KUM63268.1 - 0.0035 17.9 0.1 1.4 9.6 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KUM63268.1 - 0.004 17.4 0.1 1.3 9.3 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KUM63268.1 - 0.024 14.4 1.2 29 4.8 0.1 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 KUM63268.1 - 0.028 14.2 0.1 0.95 9.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPT PF03151.11 KUM63269.1 - 2.7e-27 95.3 16.3 2.7e-27 95.3 11.3 3.0 3 1 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 KUM63269.1 - 5.2e-06 25.5 25.5 3.2e-05 23.0 17.7 2.0 1 1 0 1 1 1 1 UAA transporter family DUF914 PF06027.7 KUM63269.1 - 0.067 12.0 16.4 0.16 10.7 11.4 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) Mid2 PF04478.7 KUM63270.1 - 6.8e-09 35.3 2.2 6.8e-09 35.3 1.5 2.6 1 1 1 3 3 3 1 Mid2 like cell wall stress sensor Syndecan PF01034.15 KUM63270.1 - 0.087 12.4 0.2 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain CRA PF06589.6 KUM63270.1 - 0.43 9.8 0.0 0.43 9.8 0.0 2.9 2 1 0 2 2 2 0 Circumsporozoite-related antigen (CRA) Ndc1_Nup PF09531.5 KUM63270.1 - 0.58 8.5 9.2 0.66 8.3 6.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MAGP PF05507.6 KUM63270.1 - 2 8.2 8.3 0.45 10.3 3.3 1.7 1 1 1 2 2 2 0 Microfibril-associated glycoprotein (MAGP) Mitofilin PF09731.4 KUM63270.1 - 3.2 6.3 8.1 3.9 6.0 5.6 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF605 PF04652.11 KUM63270.1 - 7.4 5.8 31.9 10 5.3 22.1 1.2 1 0 0 1 1 1 0 Vta1 like DUF3292 PF11696.3 KUM63274.1 - 0 1026.7 0.0 0 1026.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) F_bP_aldolase PF01116.15 KUM63275.1 - 2.5e-98 328.7 0.0 2.9e-98 328.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II UCH PF00443.24 KUM63276.1 - 1.8e-43 148.6 0.1 4.1e-37 127.7 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KUM63276.1 - 3.1e-15 56.4 0.1 1.6e-14 54.0 0.1 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF4071 PF13281.1 KUM63276.1 - 0.08 11.7 0.5 2.6 6.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4071) Multi-haem_cyto PF13447.1 KUM63276.1 - 4.1 6.3 7.4 0.17 10.9 0.1 2.3 3 0 0 3 3 3 0 Seven times multi-haem cytochrome CxxCH Tmemb_cc2 PF10267.4 KUM63276.1 - 5.9 5.3 7.4 0.56 8.7 0.6 2.2 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein UQ_con PF00179.21 KUM63277.1 - 4.4e-42 142.8 0.0 5e-42 142.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KUM63277.1 - 2.1e-07 30.7 0.0 2.5e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KUM63277.1 - 0.0059 16.4 0.1 0.0079 16.0 0.0 1.4 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KUM63277.1 - 0.037 13.7 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 UEV domain CUE PF02845.11 KUM63280.1 - 2.8e-09 36.2 0.0 4.1e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 CUE domain CDC27 PF09507.5 KUM63280.1 - 0.19 10.8 5.1 0.28 10.3 3.5 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 AlaDh_PNT_N PF05222.10 KUM63281.1 - 8.7e-30 103.4 0.0 1.4e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 KUM63281.1 - 4.9e-17 62.0 0.0 7.4e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Kinesin PF00225.18 KUM63283.1 - 1.5e-41 142.2 0.0 2.4e-41 141.5 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain bZIP_2 PF07716.10 KUM63283.1 - 0.0017 18.1 2.9 0.0047 16.7 2.0 1.8 1 0 0 1 1 1 1 Basic region leucine zipper DUF2681 PF10883.3 KUM63283.1 - 0.047 13.8 0.4 0.13 12.4 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Cep57_CLD PF14073.1 KUM63283.1 - 7.8 6.2 15.6 49 3.6 8.4 2.2 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 RTA1 PF04479.8 KUM63285.1 - 4.4e-17 62.3 4.4 8e-17 61.4 3.0 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF2754 PF10953.3 KUM63285.1 - 0.091 12.8 2.9 0.61 10.1 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) Kinesin PF00225.18 KUM63286.1 - 4.6e-07 28.8 0.0 5.4e-07 28.6 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain DUF4066 PF13278.1 KUM63288.1 - 7e-23 80.7 0.0 8.8e-23 80.3 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KUM63288.1 - 5.7e-15 55.0 0.0 9.6e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Lactamase_B_2 PF12706.2 KUM63289.1 - 3.2e-28 98.5 0.0 4e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KUM63289.1 - 7.5e-11 42.0 0.0 1e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TPR_2 PF07719.12 KUM63290.1 - 9.8e-12 43.8 9.5 6.1e-05 22.6 0.0 6.2 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 KUM63290.1 - 2.7e-09 36.5 5.3 5e-05 22.8 0.1 4.7 4 1 1 5 5 5 2 TPR repeat TPR_1 PF00515.23 KUM63290.1 - 2.6e-08 33.1 2.0 0.0065 16.0 0.0 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 KUM63290.1 - 7.7e-08 32.1 0.9 0.13 12.1 0.0 4.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 KUM63290.1 - 6.5e-07 28.6 0.2 0.37 10.6 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KUM63290.1 - 1.1e-05 26.0 10.5 0.078 13.6 0.1 5.9 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KUM63290.1 - 2.1e-05 24.7 6.8 5.4 7.9 0.0 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_4 PF07721.9 KUM63290.1 - 3.9e-05 23.6 2.8 0.085 13.3 0.0 4.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KUM63290.1 - 5.7e-05 22.6 1.4 1.6 8.7 0.0 4.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KUM63290.1 - 0.0012 19.1 1.9 4 7.8 0.0 5.1 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.1 KUM63290.1 - 0.0039 17.0 0.5 5.5 7.0 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KUM63290.1 - 0.011 15.5 4.1 0.021 14.6 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KUM63290.1 - 0.13 12.5 0.1 41 4.7 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat PPR PF01535.15 KUM63290.1 - 0.23 11.4 3.0 13 5.9 0.1 4.7 6 0 0 6 6 5 0 PPR repeat Sel1 PF08238.7 KUM63290.1 - 2.8 8.6 8.4 5.2 7.8 0.2 4.2 3 1 0 3 3 3 0 Sel1 repeat Peptidase_S24 PF00717.18 KUM63291.1 - 0.0082 15.7 0.1 0.013 15.0 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like MFS_1 PF07690.11 KUM63292.1 - 2.3e-32 112.1 36.3 9.5e-32 110.0 25.1 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM63292.1 - 1.1e-12 47.2 26.1 2e-12 46.4 18.1 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 KUM63292.1 - 0.00022 19.7 6.5 0.00022 19.7 4.5 3.5 1 1 2 3 3 3 1 MFS/sugar transport protein Sec62 PF03839.11 KUM63292.1 - 0.063 12.6 2.9 0.21 10.9 2.0 1.9 1 0 0 1 1 1 0 Translocation protein Sec62 Sigma_reg_N PF13800.1 KUM63292.1 - 0.82 9.7 2.8 47 4.1 0.6 3.0 2 0 0 2 2 2 0 Sigma factor regulator N-terminal NAD_binding_8 PF13450.1 KUM63293.1 - 4.5e-09 36.2 0.0 1.1e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KUM63293.1 - 0.00013 22.0 0.0 0.00051 20.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KUM63293.1 - 0.0017 17.4 0.0 0.0034 16.5 0.0 1.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 KUM63293.1 - 0.011 14.8 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 KUM63293.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KUM63293.1 - 0.03 13.3 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 KUM63293.1 - 0.031 13.3 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 KUM63293.1 - 0.041 12.8 0.0 0.069 12.0 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 KUM63293.1 - 0.079 11.4 0.1 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.13 KUM63293.1 - 0.08 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain APC_CDC26 PF10471.4 KUM63294.1 - 0.00093 19.8 0.8 0.0025 18.5 0.2 2.1 2 1 0 2 2 2 1 Anaphase-promoting complex APC subunit 1 Pkinase PF00069.20 KUM63295.1 - 4.8e-66 222.5 0.0 6.3e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM63295.1 - 9.3e-32 110.1 0.0 1.9e-31 109.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KUM63295.1 - 0.00017 20.7 0.0 0.00032 19.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KUM63295.1 - 0.0016 17.4 0.0 0.0046 15.9 0.0 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KUM63295.1 - 0.0054 16.4 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KUM63295.1 - 0.033 13.5 0.1 0.07 12.4 0.0 1.5 1 1 0 1 1 1 0 RIO1 family Fungal_trans_2 PF11951.3 KUM63296.1 - 3.9e-31 108.0 0.9 1.4e-30 106.1 0.6 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM63296.1 - 1.6e-06 27.9 8.0 2.6e-06 27.2 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIB PF00382.14 KUM63298.1 - 3.2e-32 110.1 0.3 1.6e-16 59.8 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 KUM63298.1 - 2.9e-24 85.0 0.0 2.9e-24 85.0 0.0 2.9 4 0 0 4 4 4 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 KUM63298.1 - 4.3e-06 26.3 0.0 0.037 13.6 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain TF_Zn_Ribbon PF08271.7 KUM63298.1 - 0.00094 18.4 3.2 0.0026 17.0 2.2 1.8 1 0 0 1 1 1 1 TFIIB zinc-binding IBR PF01485.16 KUM63298.1 - 0.23 11.3 0.8 0.45 10.4 0.6 1.4 1 0 0 1 1 1 0 IBR domain TFIIA PF03153.8 KUM63298.1 - 2.2 8.1 18.1 4.3 7.1 12.5 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SNARE PF05739.14 KUM63300.1 - 1.6e-06 27.6 1.4 2.1e-06 27.2 1.0 1.2 1 0 0 1 1 1 1 SNARE domain Apc15p PF05841.6 KUM63301.1 - 5.3e-28 98.2 1.9 5.3e-28 98.2 1.3 2.1 2 0 0 2 2 2 1 Apc15p protein Glu_synthase PF01645.12 KUM63302.1 - 1.2e-158 527.8 0.0 1.7e-158 527.3 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 KUM63302.1 - 6.6e-140 465.8 0.0 8.9e-140 465.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 KUM63302.1 - 5.4e-118 393.4 0.0 8.4e-118 392.8 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 KUM63302.1 - 7.8e-68 227.4 1.1 1.5e-67 226.5 0.8 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 KUM63302.1 - 2.1e-22 78.8 0.1 4.7e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 KUM63302.1 - 7.4e-18 65.1 0.0 3.4e-17 63.0 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KUM63302.1 - 3.8e-10 40.1 1.4 0.00037 20.6 0.1 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM63302.1 - 1.2e-08 34.8 0.0 6e-08 32.6 0.0 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KUM63302.1 - 1.2e-07 32.0 0.1 0.00042 20.6 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KUM63302.1 - 4e-06 26.1 0.2 6.6e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 KUM63302.1 - 9.5e-06 24.7 1.1 0.00018 20.5 0.2 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KUM63302.1 - 9.9e-06 24.6 0.2 0.0002 20.3 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KUM63302.1 - 2.9e-05 22.7 0.2 7.9e-05 21.2 0.2 1.7 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 KUM63302.1 - 0.00011 21.4 0.2 0.00021 20.4 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 KUM63302.1 - 0.0006 19.4 0.1 0.046 13.2 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 KUM63302.1 - 0.00087 19.5 1.2 0.96 9.7 0.1 2.9 2 0 0 2 2 2 2 Putative NAD(P)-binding Thi4 PF01946.12 KUM63302.1 - 0.0037 16.4 0.1 0.019 14.0 0.1 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 KUM63302.1 - 0.0046 16.0 0.1 0.0089 15.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DJ-1_PfpI PF01965.19 KUM63302.1 - 0.019 14.4 0.0 0.059 12.8 0.0 1.8 1 1 0 1 1 1 0 DJ-1/PfpI family NAD_Gly3P_dh_N PF01210.18 KUM63302.1 - 0.038 13.7 0.0 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 KUM63302.1 - 0.041 13.7 0.3 0.16 11.7 0.1 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase FMN_dh PF01070.13 KUM63302.1 - 0.043 12.6 1.1 0.19 10.5 0.5 2.2 2 0 0 2 2 2 0 FMN-dependent dehydrogenase FMO-like PF00743.14 KUM63302.1 - 0.048 11.8 0.1 2.2 6.3 0.0 2.7 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like Shikimate_DH PF01488.15 KUM63302.1 - 0.1 12.6 0.1 22 5.1 0.0 2.9 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 KUM63302.1 - 0.25 10.1 5.5 0.028 13.3 0.3 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 KUM63302.1 - 1.6 8.3 3.7 0.41 10.2 0.1 1.9 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3128 PF11326.3 KUM63304.1 - 2.6e-29 101.1 1.6 2.6e-29 101.1 1.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3128) RNA12 PF10443.4 KUM63305.1 - 3.2e-163 543.2 0.0 4.5e-163 542.7 0.0 1.2 1 0 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 KUM63305.1 - 1.5e-09 37.9 0.0 4.4e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 Archaeal ATPase RRM_1 PF00076.17 KUM63305.1 - 4.9e-05 22.8 0.0 0.00027 20.5 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.1 KUM63305.1 - 0.002 18.1 0.0 0.0058 16.6 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain TIR_2 PF13676.1 KUM63305.1 - 0.0047 17.0 0.0 6.5 6.9 0.0 3.9 3 0 0 3 3 3 1 TIR domain DUF2487 PF10673.4 KUM63305.1 - 0.0057 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) RRM_6 PF14259.1 KUM63305.1 - 0.0073 16.2 0.0 0.11 12.5 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AAA_14 PF13173.1 KUM63305.1 - 0.068 13.0 0.0 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KUM63305.1 - 0.13 12.4 0.0 0.55 10.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain p450 PF00067.17 KUM63306.1 - 2.7e-13 49.2 0.0 5.5e-13 48.2 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 ILVD_EDD PF00920.16 KUM63307.1 - 4.2e-166 553.4 1.7 5.4e-166 553.0 1.2 1.1 1 0 0 1 1 1 1 Dehydratase family WD40 PF00400.27 KUM63307.1 - 2.4e-15 55.7 6.8 2.2e-08 33.6 0.0 7.1 9 0 0 9 9 9 2 WD domain, G-beta repeat DUF3639 PF12341.3 KUM63307.1 - 5.1e-10 39.1 1.4 2.2e-09 37.1 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3639) Coatomer_WDAD PF04053.9 KUM63307.1 - 6.8e-07 28.4 0.0 4.9e-06 25.5 0.0 2.0 1 1 1 2 2 2 1 Coatomer WD associated region Cytochrom_D1 PF02239.11 KUM63307.1 - 0.031 12.5 0.2 0.53 8.5 0.1 2.2 1 1 1 2 2 2 0 Cytochrome D1 heme domain DNA_pol_alpha_N PF12254.3 KUM63307.1 - 0.037 13.8 2.2 0.087 12.6 1.5 1.5 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal IKI3 PF04762.7 KUM63307.1 - 0.27 9.0 0.1 0.58 7.8 0.1 1.5 1 0 0 1 1 1 0 IKI3 family MMS1_N PF10433.4 KUM63307.1 - 0.35 8.9 0.0 3 5.8 0.0 2.2 1 1 1 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF499 PF04465.7 KUM63307.1 - 0.55 7.7 0.0 0.79 7.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF499) Cauli_VI PF01693.11 KUM63308.1 - 4.7e-33 112.9 5.0 1e-15 57.4 0.8 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 KUM63308.1 - 1.7e-27 96.3 0.0 2.8e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 RNase H Na_H_Exchanger PF00999.16 KUM63309.1 - 7e-44 149.8 20.8 8.9e-44 149.5 14.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Sars6 PF12133.3 KUM63309.1 - 0.069 12.8 0.0 0.21 11.2 0.0 1.8 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus DUF3096 PF11295.3 KUM63309.1 - 1.9 8.0 10.0 3.1 7.3 0.3 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3096) BC10 PF06726.7 KUM63312.1 - 1.7e-15 56.7 9.4 2.6e-15 56.1 6.5 1.3 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 zf-C3HC4_2 PF13923.1 KUM63313.1 - 4.8e-08 32.8 9.0 7.9e-08 32.2 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KUM63313.1 - 3.1e-07 29.9 7.7 5.2e-07 29.2 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KUM63313.1 - 8.3e-07 28.7 8.2 1.4e-06 28.0 5.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KUM63313.1 - 3e-06 26.7 5.8 5.3e-06 26.0 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KUM63313.1 - 5.9e-06 26.0 5.3 3.8e-05 23.4 4.0 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KUM63313.1 - 2.2e-05 24.0 5.5 4.2e-05 23.1 3.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KUM63313.1 - 0.01 15.5 5.0 0.014 15.1 2.5 2.0 1 1 1 2 2 2 0 RING-type zinc-finger zf-MIZ PF02891.15 KUM63313.1 - 0.73 9.3 10.3 1.9 8.0 7.0 1.8 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger UCH PF00443.24 KUM63314.1 - 3.7e-51 173.8 0.0 7.1e-51 172.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KUM63314.1 - 7.5e-18 64.9 0.0 5.8e-17 62.0 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HNOBA PF07701.9 KUM63314.1 - 0.032 13.4 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Heme NO binding associated DUF601 PF04642.7 KUM63314.1 - 2.8 7.2 12.1 4.5 6.5 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF601 DLH PF01738.13 KUM63315.1 - 2e-31 109.0 0.0 2.4e-31 108.7 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KUM63315.1 - 1.3e-07 31.4 0.0 1.8e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 KUM63315.1 - 0.0042 16.8 0.1 0.19 11.3 0.0 2.1 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 KUM63315.1 - 0.014 14.8 0.0 0.029 13.8 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KUM63315.1 - 0.038 13.8 0.0 9.1 6.0 0.0 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KUM63315.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.4 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2305 PF10230.4 KUM63315.1 - 0.16 11.3 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) ERG4_ERG24 PF01222.12 KUM63316.1 - 8.1e-142 472.7 21.5 9.3e-142 472.5 14.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family NMO PF03060.10 KUM63317.1 - 2.8e-41 141.7 9.5 1.7e-39 135.9 6.6 2.1 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KUM63317.1 - 2e-09 36.8 0.0 1.9e-07 30.3 0.0 2.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KUM63317.1 - 6.1e-09 35.1 3.3 9.5e-09 34.5 2.3 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KUM63317.1 - 0.0022 16.9 1.2 0.005 15.8 0.8 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase GspH PF12019.3 KUM63317.1 - 0.0038 17.3 0.7 0.33 11.1 0.1 2.4 2 0 0 2 2 2 1 Type II transport protein GspH FMN_dh PF01070.13 KUM63318.1 - 1.7e-106 356.0 0.0 2e-106 355.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KUM63318.1 - 9.9e-22 76.5 0.0 3.3e-21 74.8 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 KUM63318.1 - 1.9e-07 30.2 0.1 0.002 17.0 0.0 3.1 3 0 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KUM63318.1 - 3.7e-05 22.8 0.0 6.4e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ATP11 PF06644.6 KUM63318.1 - 0.02 14.4 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 ATP11 protein His_biosynth PF00977.16 KUM63318.1 - 0.023 13.9 0.0 0.25 10.5 0.0 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein B2-adapt-app_C PF09066.5 KUM63318.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain DUF998 PF06197.8 KUM63319.1 - 0.019 14.2 4.1 0.92 8.7 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF998) DUF202 PF02656.10 KUM63319.1 - 0.043 14.0 8.6 0.41 10.8 6.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF202) 6PF2K PF01591.13 KUM63320.1 - 5.4e-71 238.1 0.0 1.3e-50 171.5 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KUM63320.1 - 2.4e-30 105.7 0.2 6.3e-30 104.3 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KUM63320.1 - 1.4e-08 34.7 0.0 0.00092 19.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KUM63320.1 - 0.00082 20.1 0.0 0.0046 17.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 KUM63320.1 - 0.068 12.3 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DSBA PF01323.15 KUM63321.1 - 4.5e-31 107.9 0.0 8.7e-30 103.7 0.0 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain VTC PF09359.5 KUM63322.1 - 8.1e-89 297.3 0.1 8.1e-89 297.3 0.0 1.5 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 KUM63322.1 - 7.2e-21 75.1 10.8 6.8e-14 52.3 0.4 3.3 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 KUM63322.1 - 6.7e-11 42.2 4.6 9.9e-11 41.7 2.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Bax1-I PF01027.15 KUM63322.1 - 0.023 14.3 1.0 0.037 13.6 0.7 1.2 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF3815 PF12821.2 KUM63322.1 - 0.028 14.3 0.3 0.042 13.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3815) EamA PF00892.15 KUM63322.1 - 0.067 13.2 0.9 0.13 12.3 0.6 1.3 1 0 0 1 1 1 0 EamA-like transporter family NUDIX PF00293.23 KUM63323.1 - 3.1e-14 52.7 0.1 7.7e-14 51.4 0.1 1.6 1 1 0 1 1 1 1 NUDIX domain MFS_1 PF07690.11 KUM63325.1 - 1.5e-44 152.1 15.8 1.5e-44 152.1 10.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM63325.1 - 1.7e-07 30.1 6.6 3.2e-07 29.2 4.6 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter DUF791 PF05631.9 KUM63325.1 - 0.00017 20.3 0.9 0.00017 20.3 0.6 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF791) TRI12 PF06609.8 KUM63325.1 - 0.00067 17.9 0.9 0.001 17.3 0.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MT PF12777.2 KUM63325.1 - 0.12 11.0 0.1 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor DUF1129 PF06570.6 KUM63325.1 - 0.18 11.1 3.2 11 5.2 0.0 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF1129) Cation_ATPase_C PF00689.16 KUM63325.1 - 6.1 6.3 9.2 0.41 10.1 1.6 2.5 2 1 1 3 3 3 0 Cation transporting ATPase, C-terminus dCMP_cyt_deam_1 PF00383.17 KUM63327.1 - 0.00029 20.4 0.2 0.3 10.7 0.1 2.5 2 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Na_Ca_ex PF01699.19 KUM63328.1 - 7.7e-27 93.6 28.3 1.2e-13 50.8 10.5 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Arm PF00514.18 KUM63329.1 - 5.9e-22 76.6 4.5 2.3e-05 24.0 0.0 8.6 10 0 0 10 10 10 4 Armadillo/beta-catenin-like repeat HEAT PF02985.17 KUM63329.1 - 5.6e-06 25.9 1.4 4 7.7 0.1 6.6 5 1 1 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 KUM63329.1 - 0.0032 17.7 9.1 0.093 13.0 0.0 6.1 7 1 1 8 8 8 1 HEAT repeats Ric8 PF10165.4 KUM63329.1 - 0.01 14.7 0.0 0.98 8.1 0.0 3.4 4 0 0 4 4 4 0 Guanine nucleotide exchange factor synembryn Cyclin PF08613.6 KUM63330.1 - 8.1e-30 104.2 0.0 1.3e-29 103.5 0.0 1.5 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KUM63330.1 - 3.9e-05 23.2 0.0 5.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ribosomal_60s PF00428.14 KUM63330.1 - 0.16 12.3 0.2 1.1 9.7 0.0 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein GST_N_3 PF13417.1 KUM63331.1 - 3.7e-27 94.3 0.4 7.4e-27 93.3 0.3 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KUM63331.1 - 4.3e-18 65.0 0.1 1.1e-17 63.7 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KUM63331.1 - 1.3e-07 31.6 0.1 2.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KUM63331.1 - 2.8e-07 30.3 0.2 9.1e-07 28.6 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KUM63331.1 - 8.2e-05 22.5 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KUM63331.1 - 0.0019 18.6 0.0 0.0034 17.8 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 KUM63331.1 - 0.092 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin Fructosamin_kin PF03881.9 KUM63332.1 - 1.6e-86 289.8 0.0 1.8e-86 289.6 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KUM63332.1 - 4.5e-05 23.2 0.0 7.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family CTP_transf_1 PF01148.15 KUM63333.1 - 3.3e-81 272.7 26.0 4e-81 272.4 18.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Cyclin_N PF00134.18 KUM63334.1 - 2.3e-13 49.7 0.0 6e-10 38.7 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain DUF3636 PF12331.3 KUM63335.1 - 1.6e-55 186.8 0.3 3.6e-55 185.6 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) Atg14 PF10186.4 KUM63335.1 - 0.072 12.0 2.5 0.12 11.2 1.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Vip3A_N PF12495.3 KUM63335.1 - 0.14 11.8 0.2 0.25 11.0 0.1 1.3 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal DUF730 PF05325.6 KUM63335.1 - 2.1 8.1 4.4 1.1 9.1 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF730) Tic20 PF09685.5 KUM63336.1 - 9.8e-07 28.7 2.5 1.4e-06 28.2 1.7 1.1 1 0 0 1 1 1 1 Tic20-like protein RNase_H2-Ydr279 PF09468.5 KUM63337.1 - 1.9e-89 299.8 1.0 2.5e-89 299.4 0.7 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) zf-primase PF09329.6 KUM63338.1 - 4.6e-19 67.7 1.3 7.9e-19 66.9 0.9 1.4 1 0 0 1 1 1 1 Primase zinc finger TPP_enzyme_N PF02776.13 KUM63339.1 - 1.2e-57 194.0 0.1 5.9e-57 191.8 0.0 2.1 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KUM63339.1 - 8e-48 161.8 0.0 1.4e-46 157.8 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KUM63339.1 - 3.6e-36 123.9 0.1 8.1e-36 122.8 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 KUM63339.1 - 0.069 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg FHA PF00498.21 KUM63340.1 - 7.5e-13 48.4 0.0 2.2e-12 46.9 0.0 1.9 1 0 0 1 1 1 1 FHA domain DnaJ PF00226.26 KUM63341.1 - 1.4e-10 40.7 0.7 2.5e-10 39.9 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain ESSS PF10183.4 KUM63341.1 - 0.044 14.1 0.3 0.57 10.5 0.1 2.3 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Iron_traffic PF04362.9 KUM63341.1 - 0.084 12.3 0.4 0.17 11.3 0.3 1.4 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking Methyltransf_31 PF13847.1 KUM63342.1 - 4.6e-11 42.5 0.1 9.4e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KUM63342.1 - 3.5e-10 39.4 0.1 7.8e-10 38.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 KUM63342.1 - 7.3e-09 36.2 0.1 2.6e-08 34.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM63342.1 - 1.8e-08 34.7 0.0 5.3e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KUM63342.1 - 3.5e-08 33.4 0.0 9.2e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KUM63342.1 - 1.9e-07 30.6 0.2 3.8e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KUM63342.1 - 2.5e-05 24.5 0.0 8.4e-05 22.8 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM63342.1 - 3.6e-05 23.5 0.0 8.7e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KUM63342.1 - 0.00053 18.7 0.1 0.0014 17.3 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.9 KUM63342.1 - 0.0009 18.4 0.1 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Met_10 PF02475.11 KUM63342.1 - 0.0011 18.5 0.2 0.002 17.7 0.2 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_12 PF08242.7 KUM63342.1 - 0.003 17.9 0.0 0.0094 16.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KUM63342.1 - 0.004 17.1 0.0 0.0085 16.0 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 KUM63342.1 - 0.0042 16.6 0.0 0.007 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PRMT5 PF05185.11 KUM63342.1 - 0.0078 15.1 0.1 0.025 13.5 0.1 1.8 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Ubie_methyltran PF01209.13 KUM63342.1 - 0.01 14.9 0.1 0.022 13.8 0.1 1.6 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 KUM63342.1 - 0.016 14.6 0.1 0.037 13.4 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Surfac_D-trimer PF09006.6 KUM63342.1 - 0.018 14.7 0.1 0.24 11.1 0.3 2.6 3 0 0 3 3 2 0 Lung surfactant protein D coiled-coil trimerisation CMAS PF02353.15 KUM63342.1 - 0.037 13.0 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.1 KUM63342.1 - 0.041 14.7 0.0 0.16 12.8 0.0 2.0 2 0 0 2 2 1 0 Methyltransferase domain Mo25 PF08569.6 KUM63343.1 - 1.9e-128 428.2 0.5 2.1e-128 428.0 0.3 1.0 1 0 0 1 1 1 1 Mo25-like UME PF08064.8 KUM63343.1 - 0.16 11.9 0.4 6.7 6.7 0.0 2.5 2 0 0 2 2 2 0 UME (NUC010) domain RabGAP-TBC PF00566.13 KUM63344.1 - 2.8e-32 111.9 0.0 4.6e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ADH_zinc_N_2 PF13602.1 KUM63345.1 - 2e-20 73.9 0.0 4.1e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KUM63345.1 - 2.3e-16 59.5 0.0 4e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 KUM63345.1 - 0.0035 16.9 0.4 0.0055 16.3 0.3 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase HATPase_c PF02518.21 KUM63346.1 - 3.7e-22 78.1 0.1 9.6e-22 76.8 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KUM63346.1 - 9.6e-21 73.8 0.3 3.7e-20 72.0 0.1 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KUM63346.1 - 5.1e-18 64.8 2.2 1.8e-17 63.0 0.0 2.8 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 KUM63346.1 - 4.2e-11 43.1 0.1 7.3e-07 29.5 0.0 3.3 3 1 0 3 3 3 2 PAS domain PAS_3 PF08447.6 KUM63346.1 - 2.2e-10 40.4 2.4 0.011 15.7 0.2 3.8 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.5 KUM63346.1 - 2.7e-06 27.3 0.1 5.3e-05 23.2 0.0 2.9 3 0 0 3 3 3 1 PAS fold PAS PF00989.19 KUM63346.1 - 0.00066 19.4 0.0 2 8.2 0.0 3.3 2 0 0 2 2 2 2 PAS fold LDB19 PF13002.2 KUM63346.1 - 0.026 14.0 0.6 0.067 12.6 0.4 1.6 1 0 0 1 1 1 0 Arrestin_N terminal like HATPase_c_2 PF13581.1 KUM63346.1 - 0.096 12.4 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain MotA_ExbB PF01618.11 KUM63346.1 - 0.31 10.6 0.0 1 8.9 0.0 1.8 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family KxDL PF10241.4 KUM63347.1 - 1.6e-34 117.6 1.0 2e-34 117.3 0.7 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein AAA PF00004.24 KUM63348.1 - 1.3e-53 180.6 0.0 7.1e-39 133.0 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.12 KUM63348.1 - 9.6e-13 47.5 0.1 2.3e-11 43.1 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 CDC48_N PF02359.13 KUM63348.1 - 1.2e-12 47.6 0.0 2.9e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_22 PF13401.1 KUM63348.1 - 2.4e-08 34.1 0.1 0.0011 19.1 0.0 4.1 2 2 0 3 3 3 1 AAA domain AAA_14 PF13173.1 KUM63348.1 - 2.9e-08 33.6 0.0 0.0042 16.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KUM63348.1 - 3.5e-07 29.8 1.0 0.016 14.9 0.0 3.2 3 0 0 3 3 3 2 Part of AAA domain AAA_16 PF13191.1 KUM63348.1 - 9.1e-07 29.0 0.1 0.01 15.8 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_2 PF07724.9 KUM63348.1 - 1.4e-06 28.3 0.0 0.00011 22.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 KUM63348.1 - 1.6e-06 27.4 0.1 0.0037 16.4 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 KUM63348.1 - 2.5e-06 28.2 0.1 0.016 16.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KUM63348.1 - 2.9e-06 27.0 0.0 0.0008 19.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KUM63348.1 - 4.4e-06 25.6 0.1 0.031 12.9 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus RuvB_N PF05496.7 KUM63348.1 - 4.5e-06 25.8 0.0 0.062 12.3 0.0 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KUM63348.1 - 5.5e-06 26.3 0.0 0.062 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KUM63348.1 - 8.1e-06 26.1 0.0 0.032 14.5 0.0 2.9 3 0 0 3 3 3 2 AAA domain Arch_ATPase PF01637.13 KUM63348.1 - 0.00023 20.9 1.0 7.1 6.2 0.1 4.1 3 1 1 4 4 4 0 Archaeal ATPase AAA_25 PF13481.1 KUM63348.1 - 0.00039 19.8 1.6 0.78 9.1 0.0 3.9 2 2 1 4 4 4 1 AAA domain AAA_24 PF13479.1 KUM63348.1 - 0.00039 20.0 1.5 0.15 11.6 0.1 3.5 3 1 0 3 3 3 1 AAA domain AAA_28 PF13521.1 KUM63348.1 - 0.00046 20.1 0.0 0.98 9.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KUM63348.1 - 0.0005 19.5 0.8 0.052 12.9 0.0 2.7 3 0 0 3 3 3 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 KUM63348.1 - 0.00057 19.0 0.1 0.74 8.8 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin RNA_helicase PF00910.17 KUM63348.1 - 0.00076 19.6 0.0 0.13 12.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase KaiC PF06745.8 KUM63348.1 - 0.004 16.2 0.1 0.063 12.3 0.1 2.3 2 0 0 2 2 2 1 KaiC KTI12 PF08433.5 KUM63348.1 - 0.0049 16.1 0.1 1.9 7.6 0.0 2.4 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Parvo_NS1 PF01057.12 KUM63348.1 - 0.0054 15.6 0.0 0.74 8.6 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 NACHT PF05729.7 KUM63348.1 - 0.0071 16.0 0.1 6.1 6.4 0.0 2.9 3 0 0 3 3 2 0 NACHT domain ABC_tran PF00005.22 KUM63348.1 - 0.012 15.9 0.1 0.075 13.3 0.1 2.3 2 0 0 2 2 2 0 ABC transporter AAA_3 PF07726.6 KUM63348.1 - 0.027 14.0 0.0 0.38 10.3 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KUM63348.1 - 0.03 13.1 0.1 1.7 7.4 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_11 PF13086.1 KUM63348.1 - 0.034 13.7 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 KUM63348.1 - 0.037 13.5 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.11 KUM63348.1 - 0.039 13.1 0.0 2 7.5 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein UPF0079 PF02367.12 KUM63348.1 - 0.063 12.8 0.1 2 8.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ATP-synt_ab PF00006.20 KUM63348.1 - 0.088 12.2 0.0 0.26 10.7 0.0 1.8 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 KUM63348.1 - 0.13 11.7 0.0 2.2 7.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.4 KUM63348.1 - 0.18 10.7 0.1 0.49 9.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IPT PF01745.11 KUM63348.1 - 0.18 10.9 0.1 2.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase Cir_N PF10197.4 KUM63349.1 - 4 7.5 13.3 0.056 13.4 1.6 3.4 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR PP2C PF00481.16 KUM63350.1 - 6.1e-40 137.2 0.0 9.8e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KUM63350.1 - 6.4e-06 25.7 0.0 9.7e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KUM63350.1 - 0.027 14.1 0.0 6.8 6.3 0.0 2.8 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) DASH_Duo1 PF08651.5 KUM63352.1 - 7.9e-30 102.2 2.9 8.6e-30 102.1 1.2 1.7 2 0 0 2 2 2 1 DASH complex subunit Duo1 FYRC PF05965.9 KUM63352.1 - 0.054 13.3 0.2 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 F/Y rich C-terminus DUF1822 PF08852.6 KUM63352.1 - 0.16 10.7 6.8 0.21 10.3 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) DASH_Dad2 PF08654.5 KUM63352.1 - 0.73 9.8 4.8 6.1 6.9 3.3 2.3 1 1 0 1 1 1 0 DASH complex subunit Dad2 Mcm10 PF09332.6 KUM63352.1 - 1.8 7.8 7.3 0.3 10.3 1.7 1.9 2 0 0 2 2 2 0 Mcm10 replication factor GalKase_gal_bdg PF10509.4 KUM63353.1 - 1.4e-19 69.0 0.1 2.9e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 KUM63353.1 - 1.9e-15 56.6 1.8 6.7e-15 54.9 0.6 2.4 3 0 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KUM63353.1 - 2.1e-12 47.0 0.0 4.5e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal AAA_12 PF13087.1 KUM63355.1 - 7e-42 143.0 0.0 1.2e-41 142.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KUM63355.1 - 3.4e-28 98.8 0.1 6.8e-28 97.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KUM63355.1 - 2.3e-10 40.1 0.1 1.2e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain DUF2075 PF09848.4 KUM63355.1 - 1.1e-05 24.5 0.3 0.04 12.9 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 KUM63355.1 - 0.00023 20.7 0.6 0.0036 16.8 0.1 2.8 2 1 0 2 2 2 1 AAA domain UvrD-helicase PF00580.16 KUM63355.1 - 0.0013 18.1 0.1 0.0047 16.2 0.0 1.9 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 KUM63355.1 - 0.0021 17.6 0.0 0.43 10.0 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 KUM63355.1 - 0.0041 17.2 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain ResIII PF04851.10 KUM63355.1 - 0.0058 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_18 PF13238.1 KUM63355.1 - 0.23 11.7 1.4 3.2 8.0 0.0 3.2 4 0 0 4 4 4 0 AAA domain zf-CCCH PF00642.19 KUM63355.1 - 0.42 10.3 2.4 0.86 9.3 1.6 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SapB_2 PF03489.12 KUM63356.1 - 0.1 12.6 0.2 11 6.1 0.1 2.6 2 0 0 2 2 2 0 Saposin-like type B, region 2 YtxH PF12732.2 KUM63357.1 - 0.042 14.2 11.6 0.26 11.6 3.3 2.1 1 1 1 2 2 2 0 YtxH-like protein DUF883 PF05957.8 KUM63357.1 - 0.096 13.0 7.5 0.32 11.4 2.9 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) ATP-synt_B PF00430.13 KUM63357.1 - 1.5 8.6 6.7 1.2 8.9 3.8 1.5 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) RINGv PF12906.2 KUM63358.1 - 9e-06 25.6 5.4 1.6e-05 24.8 3.7 1.4 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 KUM63358.1 - 1.3e-05 25.0 2.3 2.6e-05 24.1 1.6 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 KUM63358.1 - 0.00056 19.6 3.9 0.00095 18.9 2.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KUM63358.1 - 0.34 10.6 2.3 0.67 9.6 1.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3210 PF11489.3 KUM63359.1 - 3.5e-241 802.8 74.6 3.5e-241 802.8 51.7 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3210) Cg6151-P PF10233.4 KUM63360.1 - 1.7e-37 127.8 16.5 2e-37 127.6 11.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF4149 PF13664.1 KUM63360.1 - 0.78 9.8 10.6 0.14 12.2 2.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) Oxidored_q3 PF00499.15 KUM63360.1 - 4.1 7.1 17.1 46 3.7 11.9 2.0 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Ank_2 PF12796.2 KUM63361.1 - 6.9e-35 119.2 1.0 9.8e-13 48.2 0.1 3.0 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KUM63361.1 - 1.5e-21 75.0 0.1 1.9e-06 27.3 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.1 KUM63361.1 - 8.4e-17 59.6 0.3 0.00014 21.7 0.0 5.8 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.1 KUM63361.1 - 9.1e-15 54.7 0.2 9.3e-08 32.3 0.0 4.3 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM63361.1 - 3.7e-14 52.4 1.0 0.0025 18.0 0.0 5.2 3 2 4 7 7 7 3 Ankyrin repeats (many copies) CUE PF02845.11 KUM63361.1 - 0.073 12.5 0.1 5.8 6.5 0.0 2.6 2 0 0 2 2 2 0 CUE domain Vps35 PF03635.12 KUM63362.1 - 0 1040.3 0.3 0 1040.1 0.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 NST1 PF13945.1 KUM63363.1 - 2e-66 223.7 0.5 2e-66 223.7 0.3 4.4 2 2 2 4 4 4 1 Salt tolerance down-regulator Ras PF00071.17 KUM63364.1 - 7.1e-45 152.2 0.0 8.3e-45 152.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KUM63364.1 - 8.1e-15 55.3 0.0 1.6e-14 54.4 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KUM63364.1 - 3.6e-06 26.3 0.0 5.2e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KUM63364.1 - 0.013 14.7 0.0 0.024 13.8 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KUM63364.1 - 0.019 14.4 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 KUM63364.1 - 0.057 12.5 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MRP-L28 PF09812.4 KUM63365.1 - 2.5e-08 33.8 0.0 3.8e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 DUF2489 PF10675.4 KUM63365.1 - 0.062 12.9 1.8 0.097 12.3 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) MFS_1 PF07690.11 KUM63366.1 - 1e-40 139.5 29.5 1.4e-40 139.1 20.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KUM63366.1 - 0.0014 18.3 1.5 0.0041 16.8 1.1 1.9 1 0 0 1 1 1 1 MFS_1 like family Acyl_transf_3 PF01757.17 KUM63366.1 - 0.053 12.3 28.3 0.043 12.6 9.3 2.4 2 0 0 2 2 2 0 Acyltransferase family Phage_holin_5 PF06946.6 KUM63366.1 - 0.22 11.6 0.1 0.22 11.6 0.1 2.6 3 0 0 3 3 3 0 Phage holin 3HCDH_N PF02737.13 KUM63367.1 - 3e-32 111.7 0.0 4.5e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KUM63367.1 - 7.2e-15 55.1 0.1 1.3e-14 54.3 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 KUM63367.1 - 1e-05 25.3 0.1 1.5e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 KUM63367.1 - 6.8e-05 22.7 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KUM63367.1 - 0.00083 19.7 0.5 0.0022 18.3 0.3 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.19 KUM63367.1 - 0.0016 17.3 0.0 0.0024 16.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 KUM63367.1 - 0.0044 16.4 0.2 0.012 15.0 0.1 1.6 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RGS PF00615.14 KUM63368.1 - 0.062 13.4 0.1 0.68 10.0 0.1 2.1 1 1 0 1 1 1 0 Regulator of G protein signaling domain RRM_1 PF00076.17 KUM63370.1 - 3.1e-36 122.8 0.2 3.1e-17 61.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM63370.1 - 4.5e-28 97.0 0.1 2.9e-13 49.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM63370.1 - 1.6e-12 47.0 0.0 2.5e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KUM63370.1 - 0.043 13.6 3.4 2.1 8.2 0.0 2.7 3 0 0 3 3 3 0 RNA binding motif vMSA PF00695.14 KUM63370.1 - 2.3 7.3 6.1 3.5 6.7 4.2 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Thi4 PF01946.12 KUM63372.1 - 2.9e-101 337.3 0.0 3.6e-101 337.0 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KUM63372.1 - 2.3e-09 36.6 0.1 1.4e-08 34.0 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KUM63372.1 - 1.7e-05 23.8 0.3 3.3e-05 22.9 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KUM63372.1 - 4.9e-05 23.2 0.7 0.00013 21.9 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KUM63372.1 - 8.3e-05 22.4 0.2 0.00031 20.5 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KUM63372.1 - 0.00029 19.8 0.9 0.0052 15.6 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 KUM63372.1 - 0.00079 19.5 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KUM63372.1 - 0.0015 18.4 0.7 0.0023 17.8 0.2 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KUM63372.1 - 0.0043 16.1 0.1 0.0071 15.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KUM63372.1 - 0.0096 15.0 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KUM63372.1 - 0.12 10.9 0.2 0.17 10.4 0.2 1.1 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.9 KUM63372.1 - 0.17 10.3 0.5 0.35 9.2 0.4 1.5 1 0 0 1 1 1 0 HI0933-like protein MFS_1 PF07690.11 KUM63373.1 - 6.5e-30 104.0 27.0 6.5e-30 104.0 18.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily HTH_32 PF13565.1 KUM63374.1 - 3.5e-06 27.6 3.4 0.0018 19.0 0.1 2.5 1 1 2 3 3 3 2 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.13 KUM63374.1 - 0.0095 15.9 0.2 0.24 11.4 0.0 2.2 2 0 0 2 2 2 1 Transposase Complex1_LYR PF05347.10 KUM63374.1 - 0.037 13.8 0.4 0.093 12.5 0.2 1.8 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KUM63374.1 - 0.048 13.8 0.2 0.1 12.8 0.1 1.5 1 0 0 1 1 1 0 Complex1_LYR-like TRP PF06011.7 KUM63375.1 - 1.3e-130 435.9 8.0 1.6e-130 435.6 5.6 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KUM63375.1 - 9.8e-39 132.6 0.3 1.6e-38 131.9 0.2 1.3 1 0 0 1 1 1 1 ML-like domain EpsG PF14897.1 KUM63375.1 - 0.00024 20.1 2.9 0.00024 20.1 2.0 1.8 2 0 0 2 2 2 1 EpsG family TMEM154 PF15102.1 KUM63375.1 - 0.0017 18.0 5.0 1.7 8.3 1.4 3.3 3 0 0 3 3 3 2 TMEM154 protein family Shisa PF13908.1 KUM63375.1 - 1.2 9.2 9.2 1.2 9.2 0.0 3.1 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator DUF2663 PF10864.3 KUM63375.1 - 2.1 8.5 10.1 0.83 9.8 1.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2663) Exo_endo_phos PF03372.18 KUM63376.1 - 8.7e-17 61.8 0.0 1.3e-16 61.3 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Luciferase_cat PF10285.4 KUM63376.1 - 0.12 11.5 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 Luciferase catalytic domain WD40 PF00400.27 KUM63377.1 - 1.2e-57 189.8 12.2 9.6e-12 44.3 0.1 7.8 7 2 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KUM63377.1 - 1.7e-07 31.1 0.1 0.02 14.6 0.0 3.1 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KUM63377.1 - 6.3e-05 21.3 6.9 0.08 11.0 0.0 4.6 1 1 4 5 5 5 2 Nucleoporin Nup120/160 IKI3 PF04762.7 KUM63377.1 - 0.0067 14.3 0.0 0.01 13.7 0.0 1.2 1 0 0 1 1 1 1 IKI3 family ADH_zinc_N_2 PF13602.1 KUM63378.1 - 1.1e-15 58.6 0.0 1.8e-15 57.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KUM63378.1 - 5.4e-10 38.9 0.0 9.8e-10 38.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM63378.1 - 4.3e-08 32.8 0.0 1.1e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ABC2_membrane PF01061.19 KUM63379.1 - 1.6e-63 213.7 49.2 2.8e-32 111.5 13.6 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KUM63379.1 - 1e-42 145.6 0.0 1.4e-21 77.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KUM63379.1 - 5.4e-31 106.3 0.1 1.1e-22 79.6 0.0 2.6 2 0 0 2 2 2 2 CDR ABC transporter DUF258 PF03193.11 KUM63379.1 - 4.7e-05 22.6 0.3 0.00023 20.4 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC2_membrane_3 PF12698.2 KUM63379.1 - 5.8e-05 22.2 33.1 7.3e-05 21.9 6.9 3.2 3 1 1 4 4 4 2 ABC-2 family transporter protein AAA_16 PF13191.1 KUM63379.1 - 0.0002 21.4 0.9 0.0066 16.4 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KUM63379.1 - 0.00034 20.7 0.1 2.1 8.4 0.0 3.2 3 1 0 3 3 2 2 AAA domain AAA_25 PF13481.1 KUM63379.1 - 0.00064 19.1 0.0 1.2 8.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KUM63379.1 - 0.00071 18.8 0.1 0.16 11.1 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.1 KUM63379.1 - 0.00088 19.1 1.8 0.013 15.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 KUM63379.1 - 0.002 18.0 0.2 0.67 9.9 0.0 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 KUM63379.1 - 0.0028 17.3 1.9 0.65 9.6 0.1 2.6 2 0 0 2 2 2 1 NACHT domain PduV-EutP PF10662.4 KUM63379.1 - 0.0036 16.8 0.2 0.16 11.4 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 KUM63379.1 - 0.004 16.7 0.0 0.45 10.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KUM63379.1 - 0.0064 16.4 0.0 2.1 8.2 0.1 3.1 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.1 KUM63379.1 - 0.0075 16.5 0.1 0.53 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 KUM63379.1 - 0.0083 15.7 0.9 2.6 7.6 0.2 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 KUM63379.1 - 0.01 14.7 0.1 2.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.1 KUM63379.1 - 0.018 14.7 0.1 7.2 6.4 0.0 2.9 2 0 0 2 2 2 0 Part of AAA domain Miro PF08477.8 KUM63379.1 - 0.019 15.4 0.0 5.4 7.5 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 KUM63379.1 - 0.035 13.5 0.6 0.93 8.9 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 KUM63379.1 - 0.055 13.4 0.1 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.14 KUM63379.1 - 0.071 12.5 3.6 0.82 9.0 0.6 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 KUM63379.1 - 0.095 13.5 0.9 0.3 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KUM63379.1 - 0.1 12.5 0.4 0.4 10.6 0.0 2.2 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.7 KUM63379.1 - 0.16 11.0 0.0 0.47 9.5 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.1 KUM63379.1 - 0.16 11.5 5.7 0.26 10.8 0.6 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA PF00004.24 KUM63379.1 - 0.25 11.5 1.1 3.7 7.7 0.1 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 KUM63379.1 - 0.79 9.2 3.0 15 5.0 0.2 2.3 2 0 0 2 2 2 0 AAA domain adh_short PF00106.20 KUM63380.1 - 7.1e-10 39.0 0.0 1.1e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM63380.1 - 0.00023 20.8 0.0 0.00036 20.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Fungal_trans PF04082.13 KUM63381.1 - 2e-21 76.0 5.3 3.1e-21 75.4 3.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pox_A_type_inc PF04508.7 KUM63381.1 - 0.039 13.7 1.6 0.13 12.1 1.1 2.0 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat adh_short_C2 PF13561.1 KUM63382.1 - 4.4e-25 88.8 0.0 5.7e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KUM63382.1 - 4.5e-15 55.9 0.0 6.2e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM63382.1 - 3.7e-06 26.7 0.0 5.1e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM63382.1 - 0.014 14.8 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KUM63382.1 - 0.086 11.7 0.0 0.68 8.8 0.0 2.0 1 1 0 1 1 1 0 Male sterility protein MFS_1 PF07690.11 KUM63383.1 - 3.1e-32 111.6 49.5 1.2e-31 109.7 34.1 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily NADH_dh_m_C1 PF15088.1 KUM63383.1 - 0.17 11.4 1.3 0.36 10.3 0.2 2.1 2 0 0 2 2 2 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial ADH_zinc_N PF00107.21 KUM63384.1 - 7.1e-17 61.1 0.0 1.4e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM63384.1 - 1.3e-16 60.3 0.6 2.2e-16 59.5 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.14 KUM63384.1 - 0.0016 17.6 0.0 0.0027 16.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 KUM63384.1 - 0.0016 19.3 0.0 0.003 18.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 KUM63384.1 - 0.031 13.8 0.0 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CbiD PF01888.12 KUM63384.1 - 0.048 12.6 0.0 0.086 11.7 0.0 1.5 1 0 0 1 1 1 0 CbiD Amidohydro_2 PF04909.9 KUM63385.1 - 1e-30 107.2 1.2 1.1e-30 107.0 0.8 1.0 1 0 0 1 1 1 1 Amidohydrolase p450 PF00067.17 KUM63386.1 - 7.3e-45 153.3 0.0 1.3e-28 99.7 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Glyco_hydro_43 PF04616.9 KUM63387.1 - 8.9e-36 123.4 3.4 1.2e-35 122.9 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 p450 PF00067.17 KUM63388.1 - 6e-75 252.5 0.0 7.6e-75 252.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 YkyB PF14177.1 KUM63388.1 - 0.085 12.9 0.2 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 YkyB-like protein RrnaAD PF00398.15 KUM63389.1 - 1.8e-58 197.6 0.0 5.1e-58 196.1 0.0 1.6 1 1 1 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KUM63389.1 - 1.5e-10 41.1 0.0 3e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM63389.1 - 1.8e-06 27.6 0.0 3.8e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM63389.1 - 8e-06 26.4 0.0 1.6e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KUM63389.1 - 2.6e-05 23.8 0.0 4.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 KUM63389.1 - 3.3e-05 24.2 0.0 7.8e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM63389.1 - 0.00011 21.9 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KUM63389.1 - 0.00021 20.7 0.1 0.00063 19.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.7 KUM63389.1 - 0.00058 20.2 0.0 0.0013 19.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KUM63389.1 - 0.0018 17.5 0.0 0.0037 16.4 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_25 PF13649.1 KUM63389.1 - 0.0028 17.9 0.0 0.0084 16.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 KUM63389.1 - 0.0072 15.9 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 CMAS PF02353.15 KUM63389.1 - 0.0081 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 KUM63389.1 - 0.032 13.2 0.0 0.06 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_28 PF02636.12 KUM63389.1 - 0.072 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PRP1_N PF06424.7 KUM63390.1 - 4.9e-47 159.5 8.4 1.2e-28 100.0 1.9 2.8 2 0 0 2 2 2 2 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 KUM63390.1 - 6.6e-29 97.7 36.9 6.6e-05 23.2 0.3 14.3 5 3 10 15 15 14 9 Tetratricopeptide repeat TPR_16 PF13432.1 KUM63390.1 - 1.5e-26 92.3 22.9 1e-05 26.0 1.2 8.6 7 1 2 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 KUM63390.1 - 2.7e-25 88.4 17.6 1.6e-06 28.3 0.3 9.8 7 2 2 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.1 KUM63390.1 - 3.8e-15 55.2 7.4 0.001 18.7 0.0 8.6 6 3 4 10 10 10 5 TPR repeat TPR_2 PF07719.12 KUM63390.1 - 4.7e-12 44.8 15.1 0.17 11.9 0.0 9.2 10 0 0 10 10 8 4 Tetratricopeptide repeat TPR_1 PF00515.23 KUM63390.1 - 4.1e-08 32.4 0.6 0.17 11.5 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.1 KUM63390.1 - 3.6e-06 26.2 19.0 0.00035 19.7 3.9 5.2 3 2 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 KUM63390.1 - 1e-05 25.3 6.0 6.6 7.2 0.0 8.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.1 KUM63390.1 - 3.5e-05 23.2 1.2 20 5.3 0.0 6.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 KUM63390.1 - 8e-05 22.1 0.3 7.1 6.6 0.0 6.0 4 2 1 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 KUM63390.1 - 0.00013 21.7 7.8 1.6 8.7 0.0 6.7 6 1 3 9 9 8 2 Tetratricopeptide repeat TPR_4 PF07721.9 KUM63390.1 - 0.0019 18.4 10.0 6.3 7.5 0.1 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat Suf PF05843.9 KUM63390.1 - 0.017 14.8 0.7 0.5 10.0 0.0 3.3 4 1 0 4 4 4 0 Suppressor of forked protein (Suf) TPR_9 PF13371.1 KUM63390.1 - 0.087 12.6 5.4 5.4 6.9 0.0 5.0 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 KUM63390.1 - 0.098 12.5 18.4 0.22 11.4 2.5 4.8 4 1 0 5 5 5 0 Tetratricopeptide repeat NRDE-2 PF08424.5 KUM63390.1 - 0.27 10.0 11.7 0.2 10.4 0.6 4.1 2 1 0 3 3 3 0 NRDE-2, necessary for RNA interference TPR_6 PF13174.1 KUM63390.1 - 0.87 10.1 16.5 40 4.9 0.0 8.9 10 0 0 10 10 9 0 Tetratricopeptide repeat SAGA-Tad1 PF12767.2 KUM63391.1 - 1.6e-57 195.1 0.0 2e-57 194.7 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit FUSC_2 PF13515.1 KUM63392.1 - 1.1e-28 99.7 10.4 1.1e-28 99.7 7.2 2.9 2 1 1 3 3 3 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 KUM63392.1 - 2.6e-06 27.2 0.3 5.8e-06 26.0 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) ALMT PF11744.3 KUM63392.1 - 0.001 17.8 21.1 0.04 12.5 0.0 3.9 4 1 0 4 4 4 2 Aluminium activated malate transporter WHIM1 PF15612.1 KUM63392.1 - 0.074 13.0 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 FUSC PF04632.7 KUM63392.1 - 1.2 7.4 23.4 12 4.1 0.0 3.6 2 1 0 2 2 2 0 Fusaric acid resistance protein family WD40 PF00400.27 KUM63393.1 - 7.5e-44 146.0 21.9 2e-08 33.7 0.1 10.9 11 0 0 11 11 11 9 WD domain, G-beta repeat IRF PF00605.12 KUM63393.1 - 0.015 15.0 0.7 7.1 6.4 0.1 2.6 2 0 0 2 2 2 0 Interferon regulatory factor transcription factor Ribosomal_S18 PF01084.15 KUM63394.1 - 4.2e-15 55.3 0.0 5.9e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S18 ketoacyl-synt PF00109.21 KUM63396.1 - 8.6e-83 277.6 0.2 1e-82 277.4 0.1 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.18 KUM63396.1 - 1.1e-05 24.5 0.4 2.3e-05 23.5 0.3 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ketoacyl-synt_C PF02801.17 KUM63396.1 - 0.0024 17.7 0.2 0.022 14.5 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain p450 PF00067.17 KUM63398.1 - 8.9e-09 34.3 2.1 2.1e-06 26.5 0.1 2.1 1 1 1 2 2 2 2 Cytochrome P450 Neuropep_like PF15161.1 KUM63399.1 - 0.0097 15.3 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Neuropeptide-like zf-C2H2_3 PF13878.1 KUM63399.1 - 0.065 12.8 0.1 6.5 6.4 0.0 2.2 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO GSu_C4xC__C2xCH PF09698.5 KUM63399.1 - 0.085 13.0 3.6 2.6 8.2 0.4 2.3 2 0 0 2 2 2 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) Paired_CXXCH_1 PF09699.5 KUM63399.1 - 0.18 11.3 1.1 1.1 8.8 0.1 2.2 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) TPR_12 PF13424.1 KUM63401.1 - 2.1e-08 33.9 5.4 0.006 16.4 0.7 5.1 3 1 1 4 4 4 2 Tetratricopeptide repeat AAA_10 PF12846.2 KUM63401.1 - 4.7e-07 29.5 0.3 9.9e-05 21.9 0.0 3.9 3 1 0 4 4 4 1 AAA-like domain AAA_16 PF13191.1 KUM63401.1 - 5.6e-06 26.4 0.3 0.00016 21.6 0.0 3.5 4 1 0 4 4 4 1 AAA ATPase domain TPR_11 PF13414.1 KUM63401.1 - 7e-06 25.5 4.8 0.00049 19.6 0.6 3.8 3 1 2 5 5 5 2 TPR repeat AAA_22 PF13401.1 KUM63401.1 - 6.5e-05 23.0 0.0 0.00099 19.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain TPR_8 PF13181.1 KUM63401.1 - 7.2e-05 22.2 2.1 0.83 9.5 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat NACHT PF05729.7 KUM63401.1 - 0.00076 19.1 0.0 0.0036 16.9 0.0 2.3 1 0 0 1 1 1 1 NACHT domain TPR_2 PF07719.12 KUM63401.1 - 0.0009 18.9 8.9 0.89 9.6 0.1 5.4 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KUM63401.1 - 0.0019 18.6 3.5 0.73 10.6 0.0 5.1 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KUM63401.1 - 0.0033 16.9 0.5 1.3 8.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_19 PF13245.1 KUM63401.1 - 0.0038 16.9 0.0 0.015 14.9 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain TPR_7 PF13176.1 KUM63401.1 - 0.0056 16.3 9.0 0.047 13.4 0.0 5.1 6 0 0 6 6 4 1 Tetratricopeptide repeat PIF1 PF05970.9 KUM63401.1 - 0.013 14.5 0.0 0.03 13.2 0.0 1.5 1 0 0 1 1 1 0 PIF1-like helicase AAA_17 PF13207.1 KUM63401.1 - 0.024 15.4 0.0 0.12 13.1 0.0 2.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KUM63401.1 - 0.025 13.5 0.0 0.063 12.2 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 KUM63401.1 - 0.032 13.6 0.0 0.48 9.8 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF948 PF06103.6 KUM63401.1 - 0.079 12.8 3.4 0.096 12.5 1.2 2.0 2 0 0 2 2 1 0 Bacterial protein of unknown function (DUF948) TPR_17 PF13431.1 KUM63401.1 - 0.1 12.8 1.3 0.33 11.2 0.1 2.6 2 0 0 2 2 1 0 Tetratricopeptide repeat YlbD_coat PF14071.1 KUM63401.1 - 0.17 11.9 2.9 0.2 11.6 0.1 2.6 3 0 0 3 3 3 0 Putative coat protein Fungal_trans_2 PF11951.3 KUM63402.1 - 6.3e-13 48.0 2.4 9.9e-13 47.4 1.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PPR_3 PF13812.1 KUM63403.1 - 2.9e-10 39.6 0.6 0.086 13.1 0.0 7.3 6 0 0 6 6 6 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 KUM63403.1 - 2e-09 37.3 1.0 2.3 8.2 0.0 7.8 7 1 2 9 9 9 3 PPR repeat family PPR PF01535.15 KUM63403.1 - 9.1e-06 25.3 3.1 1.7 8.8 0.1 6.7 6 0 0 6 6 6 1 PPR repeat TPR_19 PF14559.1 KUM63403.1 - 0.00088 19.5 3.8 0.14 12.5 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat Mycoplasma_p37 PF06646.6 KUM63403.1 - 0.082 11.9 0.1 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 High affinity transport system protein p37 CorA PF01544.13 KUM63404.1 - 1.1e-06 27.8 0.1 1.8e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein RabGAP-TBC PF00566.13 KUM63405.1 - 1.5e-47 161.8 0.0 3.3e-47 160.7 0.0 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain UDP-g_GGTase PF06427.6 KUM63406.1 - 1.5e-67 226.9 0.0 3.1e-67 225.9 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 KUM63406.1 - 0.00079 18.8 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Myb_DNA-bind_6 PF13921.1 KUM63407.1 - 4.6e-15 55.4 6.1 1.1e-10 41.4 1.4 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KUM63407.1 - 5.6e-15 55.1 6.2 2.5e-07 30.6 0.5 2.8 2 1 0 2 2 2 2 Myb-like DNA-binding domain SUR7 PF06687.7 KUM63408.1 - 5.2e-39 134.0 8.0 6e-39 133.7 5.5 1.0 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 KUM63408.1 - 2.8e-05 23.8 10.5 2.8e-05 23.8 7.3 2.1 1 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 KUM63408.1 - 0.0053 16.0 2.7 0.0082 15.4 1.9 1.4 1 0 0 1 1 1 1 Clc-like Amastin PF07344.6 KUM63408.1 - 0.11 12.0 14.0 0.32 10.6 9.7 1.8 1 1 0 1 1 1 0 Amastin surface glycoprotein HSP70 PF00012.15 KUM63409.1 - 6e-83 278.7 1.4 6e-83 278.7 1.0 1.3 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KUM63409.1 - 2.2e-09 36.3 0.1 3.4e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Peripla_BP_6 PF13458.1 KUM63409.1 - 0.017 14.5 0.0 0.035 13.4 0.0 1.5 1 0 0 1 1 1 0 Periplasmic binding protein FAM176 PF14851.1 KUM63409.1 - 0.15 11.7 1.3 0.33 10.6 0.9 1.5 1 0 0 1 1 1 0 FAM176 family DASH_Spc19 PF08287.6 KUM63410.1 - 1.4e-52 177.3 2.0 1.8e-52 177.0 1.4 1.1 1 0 0 1 1 1 1 Spc19 Reo_sigmaC PF04582.7 KUM63410.1 - 0.19 10.8 1.1 0.31 10.1 0.7 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein COG5 PF10392.4 KUM63410.1 - 3.5 7.5 7.3 14 5.6 0.1 2.9 2 1 1 3 3 3 0 Golgi transport complex subunit 5 Raptor_N PF14538.1 KUM63412.1 - 1.3e-63 213.5 0.0 2.2e-63 212.7 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 KUM63412.1 - 1.4e-06 27.9 6.9 1.1 9.2 0.0 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 KUM63412.1 - 0.002 17.8 0.2 1.5 8.6 0.1 2.8 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Peptidase_C14 PF00656.17 KUM63412.1 - 0.0089 15.7 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Caspase domain HEAT PF02985.17 KUM63412.1 - 0.081 13.0 0.2 30 5.0 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat Atx10homo_assoc PF09759.4 KUM63412.1 - 0.23 11.2 0.0 0.54 10.0 0.0 1.6 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain Kelch_3 PF13415.1 KUM63413.1 - 3.4e-36 122.5 11.9 4.9e-08 32.9 0.1 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.1 KUM63413.1 - 8.9e-31 105.4 11.6 5.2e-06 26.1 0.0 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 KUM63413.1 - 1e-30 105.1 5.7 7.5e-06 25.7 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 KUM63413.1 - 1.2e-27 95.1 1.1 6.7e-08 31.9 0.4 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 KUM63413.1 - 1.6e-22 78.6 8.7 6.5e-07 29.2 0.5 6.4 4 1 2 6 6 6 5 Kelch motif Kelch_2 PF07646.10 KUM63413.1 - 3.4e-18 64.6 9.6 2.5e-06 27.0 0.2 6.4 6 0 0 6 6 6 4 Kelch motif RAG2 PF03089.9 KUM63413.1 - 0.0092 14.7 0.1 0.17 10.6 0.0 2.9 4 0 0 4 4 4 1 Recombination activating protein 2 LRR_4 PF12799.2 KUM63416.1 - 1.8e-13 49.7 16.3 2.1e-10 39.9 2.2 3.2 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KUM63416.1 - 4.5e-11 42.3 8.7 2.1e-08 33.7 4.3 3.0 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KUM63416.1 - 6.6e-05 22.4 10.9 0.018 14.9 0.2 5.4 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_7 PF13504.1 KUM63416.1 - 0.00026 20.6 4.9 0.018 15.1 0.2 3.6 3 0 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 KUM63416.1 - 0.035 14.1 1.8 3.1 8.1 0.2 3.0 2 0 0 2 2 2 0 Leucine Rich repeat LRR_5 PF13306.1 KUM63416.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Leucine rich repeats (6 copies) adh_short PF00106.20 KUM63417.1 - 8.5e-32 110.3 0.5 1.2e-31 109.9 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM63417.1 - 1e-17 64.7 0.0 1.3e-17 64.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM63417.1 - 1.8e-17 63.5 0.2 2.7e-17 63.0 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KUM63417.1 - 7.6e-10 39.0 0.1 1.4e-09 38.2 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KUM63417.1 - 8.7e-05 22.0 0.0 0.00032 20.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KUM63417.1 - 9.6e-05 21.4 0.0 0.00015 20.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 KUM63417.1 - 0.0028 17.4 0.0 0.0091 15.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 KUM63417.1 - 0.021 13.9 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NmrA PF05368.8 KUM63417.1 - 0.046 12.9 0.0 0.074 12.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family zf-RING_2 PF13639.1 KUM63418.1 - 4.6e-14 51.9 6.0 7.8e-14 51.2 4.2 1.4 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 KUM63418.1 - 5.1e-11 42.1 0.0 1.1e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 KUM63418.1 - 3.4e-09 36.5 5.8 5.6e-09 35.8 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KUM63418.1 - 2.1e-08 34.1 4.2 3.9e-08 33.2 2.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KUM63418.1 - 2.6e-08 33.3 3.9 4.4e-08 32.6 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KUM63418.1 - 5.6e-08 32.3 3.3 8.7e-08 31.7 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KUM63418.1 - 1.4e-07 31.0 2.9 2.4e-07 30.3 2.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KUM63418.1 - 0.00072 19.3 1.2 0.0013 18.4 0.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KUM63418.1 - 0.047 13.4 3.4 0.11 12.2 2.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KUM63418.1 - 0.058 13.2 3.9 0.16 11.8 2.8 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 KUM63418.1 - 0.095 12.6 2.6 0.25 11.3 1.8 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 KUM63418.1 - 0.11 12.6 4.4 0.2 11.6 3.0 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 KUM63418.1 - 0.3 10.7 2.9 0.54 9.8 2.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 KUM63418.1 - 0.61 10.1 3.9 1.3 9.1 2.7 1.5 1 0 0 1 1 1 0 RING-like domain Pkinase PF00069.20 KUM63419.1 - 2.4e-38 131.8 0.0 3e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM63419.1 - 7.5e-14 51.4 0.0 1.1e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KUM63419.1 - 2.1e-05 24.3 0.0 0.0015 18.3 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Prp31_C PF09785.4 KUM63420.1 - 0.048 14.1 0.9 0.051 14.0 0.6 1.1 1 0 0 1 1 1 0 Prp31 C terminal domain Arb2 PF09757.4 KUM63421.1 - 3.2e-08 33.2 0.0 5.2e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain Vma12 PF11712.3 KUM63422.1 - 1.1e-32 112.7 0.0 1.4e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Adaptin_N PF01602.15 KUM63423.1 - 8.2e-110 367.5 0.1 1.1e-109 367.2 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 KUM63423.1 - 1.5e-58 196.9 1.1 3.6e-58 195.6 0.7 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 KUM63423.1 - 1.5e-14 54.0 0.6 2.7e-05 24.3 0.0 6.1 2 2 4 6 6 6 5 HEAT repeats HEAT PF02985.17 KUM63423.1 - 3.7e-05 23.4 3.9 0.34 11.1 0.1 5.6 5 0 0 5 5 5 1 HEAT repeat HEAT_PBS PF03130.11 KUM63423.1 - 0.0027 18.0 1.8 12 6.7 0.0 5.2 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 KUM63423.1 - 0.0084 16.5 2.9 0.031 14.7 0.3 3.2 3 0 0 3 3 3 1 HEAT-like repeat Cnd1 PF12717.2 KUM63423.1 - 0.021 14.7 3.9 0.11 12.3 0.1 3.5 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 F-box-like PF12937.2 KUM63424.1 - 3.3e-06 26.7 0.5 8.4e-06 25.4 0.0 2.0 2 0 0 2 2 2 1 F-box-like PX PF00787.19 KUM63425.1 - 4.1e-14 52.3 0.0 4.6e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 PX domain Caudal_act PF04731.7 KUM63425.1 - 0.028 14.7 0.4 0.072 13.3 0.1 1.7 1 1 0 2 2 2 0 Caudal like protein activation region SIP1 PF04938.7 KUM63426.1 - 0.00016 21.1 2.4 0.029 13.7 0.0 3.4 2 1 0 3 3 3 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) DDE_3 PF13358.1 KUM63427.1 - 6.1e-29 100.6 0.1 1.3e-28 99.5 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_1 PF03184.14 KUM63427.1 - 3.8e-08 32.7 0.0 7.6e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 KUM63427.1 - 1.7e-07 31.3 0.0 4.6e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain HTH_32 PF13565.1 KUM63427.1 - 5.4e-06 27.1 0.0 1.1e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_33 PF13592.1 KUM63427.1 - 0.016 14.7 0.1 0.055 13.0 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn helix bZIP_1 PF00170.16 KUM63428.1 - 2e-10 40.4 8.8 3.4e-10 39.7 6.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KUM63428.1 - 7.7e-06 25.6 12.9 8e-06 25.5 8.2 1.6 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 KUM63428.1 - 0.0017 18.6 7.0 0.0027 17.9 4.8 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor MIS13 PF08202.6 KUM63428.1 - 0.0032 16.5 2.3 0.0043 16.1 1.6 1.1 1 0 0 1 1 1 1 Mis12-Mtw1 protein family HOOK PF05622.7 KUM63428.1 - 0.005 14.7 2.4 0.0067 14.3 1.7 1.0 1 0 0 1 1 1 1 HOOK protein DUF972 PF06156.8 KUM63428.1 - 0.014 15.7 1.0 0.014 15.7 0.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF972) TMF_TATA_bd PF12325.3 KUM63428.1 - 0.015 14.9 3.9 0.028 14.1 2.7 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Herpes_UL6 PF01763.11 KUM63428.1 - 0.037 12.2 1.3 0.048 11.8 0.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like FlaC_arch PF05377.6 KUM63428.1 - 0.083 12.8 0.2 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.14 KUM63428.1 - 0.083 10.7 0.6 0.1 10.4 0.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Glutaredoxin2_C PF04399.8 KUM63428.1 - 0.12 11.9 1.5 0.22 11.1 1.0 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DUF904 PF06005.7 KUM63428.1 - 0.13 12.5 4.2 0.078 13.2 1.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Effector_1 PF04518.7 KUM63428.1 - 0.2 10.6 3.9 0.26 10.2 2.7 1.1 1 0 0 1 1 1 0 Effector from type III secretion system APG6 PF04111.7 KUM63428.1 - 0.21 10.5 3.9 0.29 10.1 2.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF812 PF05667.6 KUM63428.1 - 0.25 9.7 7.6 0.33 9.3 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF724 PF05266.9 KUM63428.1 - 0.34 10.5 6.7 0.52 9.9 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DivIC PF04977.10 KUM63428.1 - 0.63 9.5 3.6 1.1 8.7 2.5 1.5 1 0 0 1 1 1 0 Septum formation initiator IncA PF04156.9 KUM63428.1 - 0.64 9.5 4.1 1.1 8.8 2.8 1.3 1 0 0 1 1 1 0 IncA protein Phage_lysis PF03245.8 KUM63428.1 - 1.5 8.8 10.1 5.3 7.0 7.0 1.8 1 1 0 1 1 1 0 Bacteriophage Rz lysis protein Phosducin PF02114.11 KUM63429.1 - 3.2e-10 39.1 0.2 4e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 Phosducin Glyco_hydro_72 PF03198.9 KUM63430.1 - 5.3e-133 442.8 5.0 6.4e-133 442.5 3.4 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 KUM63430.1 - 1e-06 28.1 0.3 6.8e-06 25.4 0.2 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 KUM63430.1 - 3.4e-05 22.8 0.2 5.9e-05 22.1 0.1 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain tRNA-synt_2 PF00152.15 KUM63431.1 - 2.3e-74 250.1 0.2 3.1e-74 249.7 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KUM63431.1 - 2.1e-06 27.4 0.1 4e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Hydrolase_6 PF13344.1 KUM63432.1 - 3.4e-25 87.8 0.0 6.9e-25 86.8 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KUM63432.1 - 1e-15 57.1 0.0 7.5e-15 54.4 0.0 2.4 3 0 0 3 3 3 1 HAD-hyrolase-like HAD_2 PF13419.1 KUM63432.1 - 8.1e-06 26.1 0.0 0.014 15.6 0.0 3.5 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KUM63432.1 - 0.00012 22.5 0.0 0.058 13.7 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase DAGK_cat PF00781.19 KUM63432.1 - 0.037 13.4 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Pkinase PF00069.20 KUM63433.1 - 2.1e-14 53.3 0.4 5.2e-13 48.7 0.3 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM63433.1 - 6.9e-07 28.6 0.2 1e-06 28.0 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 KUM63433.1 - 0.033 13.2 0.2 0.043 12.8 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1436 PF07262.6 KUM63433.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1436) ABC_tran PF00005.22 KUM63434.1 - 3.7e-35 121.1 0.0 8.2e-35 120.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KUM63434.1 - 6.8e-15 55.2 4.4 6.8e-15 55.2 3.0 2.1 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 KUM63434.1 - 3.2e-08 33.0 0.0 5.1e-06 25.8 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KUM63434.1 - 0.0013 18.7 0.2 0.003 17.5 0.2 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 KUM63434.1 - 0.0014 18.6 0.1 0.018 15.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KUM63434.1 - 0.0028 16.7 0.1 0.013 14.6 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.1 KUM63434.1 - 0.0035 17.6 1.0 0.0047 17.2 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 KUM63434.1 - 0.0037 18.0 0.0 0.0098 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Herpes_gE PF02480.11 KUM63434.1 - 0.0042 15.4 0.0 0.011 14.0 0.0 1.6 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E AAA_18 PF13238.1 KUM63434.1 - 0.0055 17.0 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KUM63434.1 - 0.0061 16.7 0.0 0.017 15.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KUM63434.1 - 0.014 15.2 0.0 0.3 10.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KUM63434.1 - 0.016 14.7 0.1 0.04 13.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 KUM63434.1 - 0.026 14.7 0.0 0.22 11.7 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 KUM63434.1 - 0.029 14.1 0.6 0.086 12.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF1510 PF07423.6 KUM63434.1 - 0.043 13.1 2.4 0.35 10.2 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) NB-ARC PF00931.17 KUM63434.1 - 0.057 12.2 0.1 0.11 11.3 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain MobB PF03205.9 KUM63434.1 - 0.093 12.4 0.2 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 KUM63434.1 - 0.11 12.0 0.1 0.27 10.8 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 KUM63434.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 cobW PF02492.14 KUM63434.1 - 0.12 11.7 0.1 0.34 10.3 0.1 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.15 KUM63434.1 - 0.13 10.9 1.0 0.34 9.5 0.0 2.1 3 0 0 3 3 3 0 G-protein alpha subunit EphA2_TM PF14575.1 KUM63434.1 - 0.57 10.6 3.1 9.3 6.7 0.0 3.4 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Intg_mem_TP0381 PF09529.5 KUM63434.1 - 3 7.0 8.9 0.047 12.9 0.4 2.2 4 0 0 4 4 4 0 Integral membrane protein (intg_mem_TP0381) DUF4512 PF14975.1 KUM63435.1 - 5.9 7.7 6.0 16 6.4 4.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) DUF2067 PF09840.4 KUM63436.1 - 0.034 13.6 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) DUF261 PF03196.8 KUM63436.1 - 0.059 13.3 0.0 0.093 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF261 FHA PF00498.21 KUM63438.1 - 3.9e-16 58.9 0.0 8.1e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain DUF2408 PF10303.4 KUM63438.1 - 0.016 15.3 1.6 0.016 15.3 1.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) Hemerythrin PF01814.18 KUM63438.1 - 0.085 13.0 5.5 0.13 12.3 0.9 3.0 4 0 0 4 4 4 0 Hemerythrin HHE cation binding domain EAP30 PF04157.11 KUM63438.1 - 0.09 11.9 4.8 0.31 10.1 3.4 1.9 1 0 0 1 1 1 0 EAP30/Vps36 family DUF1366 PF07104.6 KUM63438.1 - 0.73 9.4 12.9 3.2 7.4 3.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1366) Spectrin PF00435.16 KUM63438.1 - 2.8 8.2 13.1 4 7.7 2.2 2.9 3 0 0 3 3 3 0 Spectrin repeat CENP-Q PF13094.1 KUM63438.1 - 4.6 7.2 31.7 0.49 10.4 8.5 3.6 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1664 PF07889.7 KUM63438.1 - 6.7 6.5 7.1 25 4.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) COG2 PF06148.6 KUM63438.1 - 7 6.5 13.9 0.081 12.7 2.5 2.5 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TBPIP PF07106.8 KUM63438.1 - 7.7 6.0 16.1 8.3 5.9 0.4 3.1 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Rpp20 PF12328.3 KUM63439.1 - 2e-49 166.9 15.9 3.7e-49 166.0 11.0 1.4 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 KUM63439.1 - 2.4e-24 84.7 1.7 3.9e-24 84.0 1.2 1.4 1 0 0 1 1 1 1 Alba FYDLN_acid PF09538.5 KUM63439.1 - 0.005 17.3 10.7 0.83 10.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (FYDLN_acid) DUF1529 PF07485.6 KUM63439.1 - 0.022 14.4 0.2 0.04 13.6 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1259) CDC45 PF02724.9 KUM63439.1 - 0.026 12.6 4.6 0.032 12.2 3.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Opi1 PF08618.5 KUM63439.1 - 0.095 11.5 11.5 0.036 12.9 5.8 1.7 1 1 1 2 2 2 0 Transcription factor Opi1 SynMuv_product PF06047.6 KUM63439.1 - 4.8 6.9 8.1 0.28 10.9 0.6 2.3 2 0 0 2 2 2 0 Ras-induced vulval development antagonist Romo1 PF10247.4 KUM63440.1 - 5.3e-29 100.2 13.6 6.7e-29 99.8 9.4 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 TMEM141 PF15110.1 KUM63440.1 - 1.7 9.0 4.0 2.9 8.2 0.6 2.0 1 1 1 2 2 2 0 TMEM141 protein family Tim17 PF02466.14 KUM63440.1 - 3.2 7.8 9.0 16 5.5 6.2 1.9 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Rsm22 PF09243.5 KUM63441.1 - 3.3e-32 111.6 0.0 4.4e-30 104.6 0.0 2.7 2 1 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_18 PF12847.2 KUM63441.1 - 0.095 13.2 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KUM63441.1 - 0.12 12.8 0.0 0.33 11.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Rogdi_lz PF10259.4 KUM63442.1 - 4.8e-77 258.7 0.0 5.6e-77 258.5 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein APP_N PF02177.11 KUM63442.1 - 0.16 11.9 0.1 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Amyloid A4 N-terminal heparin-binding Ribosomal_S14 PF00253.16 KUM63443.1 - 7.5e-19 66.8 0.5 4.8e-18 64.2 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e SpoIIIAH PF12685.2 KUM63443.1 - 0.16 11.4 0.3 0.23 10.9 0.1 1.5 1 1 1 2 2 2 0 SpoIIIAH-like protein Amidohydro_1 PF01979.15 KUM63444.1 - 3.2e-21 76.3 0.2 4.1e-14 52.9 0.1 2.9 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 KUM63444.1 - 7.1e-21 75.4 0.8 2.6e-20 73.6 0.5 1.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KUM63444.1 - 8.4e-10 38.3 0.9 2.8e-09 36.6 0.1 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 KUM63444.1 - 7e-07 28.7 0.0 0.0012 18.1 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Methyltransf_2 PF00891.13 KUM63445.1 - 9.4e-33 113.3 0.3 1.7e-32 112.5 0.2 1.4 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 KUM63445.1 - 0.0041 16.9 0.1 0.019 14.8 0.0 2.2 2 0 0 2 2 2 1 Dimerisation domain HTH_24 PF13412.1 KUM63445.1 - 0.032 13.5 0.0 0.12 11.7 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_27 PF13463.1 KUM63445.1 - 0.11 12.8 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain CENP-F_leu_zip PF10473.4 KUM63446.1 - 6e-07 29.3 35.0 0.024 14.5 7.9 5.5 3 1 2 6 6 6 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 KUM63446.1 - 1.3e-05 24.9 35.1 2.1e-05 24.2 0.3 3.9 3 1 0 4 4 4 2 IncA protein ADIP PF11559.3 KUM63446.1 - 0.011 15.5 5.5 0.011 15.5 3.8 4.8 3 1 2 5 5 5 0 Afadin- and alpha -actinin-Binding Sec3_C_2 PF15278.1 KUM63446.1 - 0.034 14.2 0.5 0.15 12.1 0.1 2.4 2 0 0 2 2 2 0 Sec3 exocyst complex subunit Reo_sigmaC PF04582.7 KUM63446.1 - 0.046 12.8 12.1 0.087 11.9 1.8 3.0 2 1 1 3 3 3 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 KUM63446.1 - 0.54 9.9 27.1 84 2.9 0.0 4.1 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein ACCA PF03255.9 KUM63446.1 - 1.5 8.3 9.0 1.8 8.1 0.7 3.1 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Taxilin PF09728.4 KUM63446.1 - 1.7 7.6 26.6 0.44 9.5 13.6 2.5 2 1 0 2 2 2 0 Myosin-like coiled-coil protein FliD_N PF02465.13 KUM63446.1 - 4.1 7.8 9.7 3.9 7.8 0.2 4.1 5 0 0 5 5 5 0 Flagellar hook-associated protein 2 N-terminus Filament PF00038.16 KUM63446.1 - 4.1 6.7 37.6 0.5 9.7 18.7 4.0 3 1 0 3 3 3 0 Intermediate filament protein FAD_binding_3 PF01494.14 KUM63447.1 - 4.1e-13 49.1 0.0 6.4e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Peptidase_M24 PF00557.19 KUM63448.1 - 1.3e-44 152.2 0.0 1.6e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 KUM63448.1 - 0.00095 18.9 5.3 0.00095 18.9 3.7 2.4 2 0 0 2 2 2 1 MYND finger WD40 PF00400.27 KUM63449.1 - 3.4e-44 147.2 8.6 3.3e-11 42.6 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat PQQ_2 PF13360.1 KUM63449.1 - 0.00036 20.0 0.0 0.0014 18.1 0.0 2.1 1 1 0 1 1 1 1 PQQ-like domain zf-C2H2_2 PF12756.2 KUM63450.1 - 8.8e-10 38.6 7.9 0.003 17.6 0.1 3.7 1 1 2 3 3 3 3 C2H2 type zinc-finger (2 copies) MMR_HSR1 PF01926.18 KUM63450.1 - 3.5e-08 33.4 0.0 8.3e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KUM63450.1 - 6.2e-05 22.2 0.0 0.00017 20.8 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KUM63450.1 - 0.00055 19.8 0.2 0.01 15.6 0.0 4.3 2 2 2 4 4 4 2 Dynamin family AIG1 PF04548.11 KUM63450.1 - 0.0012 18.0 0.0 0.0012 18.0 0.0 2.4 2 1 0 2 2 1 1 AIG1 family zf-LYAR PF08790.6 KUM63450.1 - 0.0013 18.3 2.9 8.1 6.2 0.1 3.6 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2H2 PF00096.21 KUM63450.1 - 0.0038 17.4 7.1 0.87 10.0 0.7 3.7 3 0 0 3 3 3 1 Zinc finger, C2H2 type DUF445 PF04286.7 KUM63450.1 - 0.0043 16.6 8.0 0.0053 16.3 5.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF445) IIGP PF05049.8 KUM63450.1 - 0.0082 15.0 2.7 0.013 14.3 0.0 2.1 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) zf-C2H2_6 PF13912.1 KUM63450.1 - 0.047 13.6 11.9 0.27 11.2 1.5 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Exonuc_VII_L PF02601.10 KUM63450.1 - 0.088 11.9 14.7 0.13 11.4 10.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_29 PF13555.1 KUM63450.1 - 0.1 12.1 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KUM63450.1 - 0.11 12.8 0.0 0.11 12.8 0.0 2.9 2 1 0 2 2 1 0 ABC transporter zf-CCHH PF10283.4 KUM63450.1 - 0.11 12.3 4.7 23 4.9 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger (CX5CX6HX5H) motif zf-met PF12874.2 KUM63450.1 - 0.12 12.6 1.2 0.6 10.3 0.2 2.6 3 0 0 3 3 2 0 Zinc-finger of C2H2 type Miro PF08477.8 KUM63450.1 - 0.14 12.6 2.8 0.26 11.7 0.0 2.6 2 1 0 2 2 2 0 Miro-like protein OmpH PF03938.9 KUM63450.1 - 0.59 10.0 39.4 0.079 12.9 17.8 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) AAA_23 PF13476.1 KUM63450.1 - 0.75 10.0 0.0 0.75 10.0 0.0 3.0 2 1 0 2 2 1 0 AAA domain Asp-B-Hydro_N PF05279.6 KUM63450.1 - 0.91 9.3 21.8 1.3 8.7 15.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region AAA_18 PF13238.1 KUM63450.1 - 2.1 8.6 0.0 2.1 8.6 0.0 3.3 2 1 0 2 2 1 0 AAA domain LMBR1 PF04791.11 KUM63450.1 - 2.4 6.6 3.4 3.1 6.2 2.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3829 PF12889.2 KUM63450.1 - 4.4 6.4 15.9 7.1 5.7 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Peptidase_C6 PF00851.13 KUM63450.1 - 8.8 4.8 14.9 93 1.4 11.4 1.8 2 0 0 2 2 2 0 Helper component proteinase zf-C2H2_jaz PF12171.3 KUM63450.1 - 9 6.5 7.1 1.8 8.8 0.5 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding EF-hand_1 PF00036.27 KUM63451.1 - 4.3e-12 44.3 3.9 1.9e-05 23.6 0.2 3.3 3 0 0 3 3 3 2 EF hand ZZ PF00569.12 KUM63451.1 - 1.3e-11 43.8 4.8 2.4e-11 43.0 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_6 PF13405.1 KUM63451.1 - 2.2e-09 36.4 3.4 0.00019 21.0 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 KUM63451.1 - 2.5e-09 37.1 4.9 5.7e-09 35.9 2.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 KUM63451.1 - 4.9e-06 26.0 4.1 0.012 15.1 0.2 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KUM63451.1 - 0.00085 18.5 7.2 0.26 10.7 0.2 3.2 3 0 0 3 3 3 2 EF hand DUF4614 PF15391.1 KUM63451.1 - 0.43 10.3 2.1 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) MFS_1 PF07690.11 KUM63452.1 - 1.4e-20 73.3 47.5 2.7e-20 72.3 31.0 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Gly-zipper_Omp PF13488.1 KUM63452.1 - 1.4 8.5 5.8 12 5.6 0.4 2.8 2 0 0 2 2 2 0 Glycine zipper Cys_Met_Meta_PP PF01053.15 KUM63455.1 - 4.2e-34 117.4 0.0 5.5e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KUM63455.1 - 3.6e-05 22.8 0.0 5.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3506 PF12014.3 KUM63456.1 - 7e-46 155.3 0.0 1.3e-45 154.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 KUM63456.1 - 6.1e-12 45.0 0.1 2.1e-11 43.3 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KUM63456.1 - 5.2e-07 29.1 0.1 1.6e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 F-box domain DUF1748 PF08520.5 KUM63457.1 - 1.5e-35 120.6 0.1 1.6e-35 120.5 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Cornichon PF03311.9 KUM63458.1 - 2.5e-39 134.3 8.7 3.1e-39 134.0 6.0 1.1 1 0 0 1 1 1 1 Cornichon protein DUF1634 PF07843.6 KUM63458.1 - 0.04 13.5 0.2 0.058 13.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1634) DUF1673 PF07895.6 KUM63458.1 - 0.17 11.3 2.3 0.23 10.9 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) MMR_HSR1 PF01926.18 KUM63459.1 - 8.7e-09 35.3 0.0 2e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KUM63459.1 - 7.4e-06 25.2 0.0 7.4e-06 25.2 0.0 2.0 3 0 0 3 3 3 1 AIG1 family DUF258 PF03193.11 KUM63459.1 - 1.4e-05 24.3 0.1 3.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 KUM63459.1 - 0.00049 20.5 0.0 0.0018 18.7 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein Septin PF00735.13 KUM63459.1 - 0.0022 17.0 0.0 0.0074 15.3 0.0 1.8 1 0 0 1 1 1 1 Septin FeoB_N PF02421.13 KUM63459.1 - 0.048 12.9 0.0 0.099 11.9 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B DUF3040 PF11239.3 KUM63459.1 - 0.056 13.4 0.2 0.47 10.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) AAA_29 PF13555.1 KUM63459.1 - 0.072 12.6 0.2 0.2 11.1 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.18 KUM63459.1 - 0.18 11.5 11.5 3.2 7.5 0.0 4.0 3 1 1 4 4 4 0 Dynamin family MobB PF03205.9 KUM63459.1 - 0.2 11.3 1.2 0.4 10.3 0.3 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KUM63459.1 - 0.32 11.2 0.0 0.32 11.2 0.0 3.1 2 1 0 2 2 1 0 ABC transporter Atg14 PF10186.4 KUM63459.1 - 1.5 7.6 23.2 2.7 6.8 16.1 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ArgK PF03308.11 KUM63459.1 - 2.8 6.6 5.7 0.57 8.9 0.1 2.2 2 0 0 2 2 2 0 ArgK protein UNC-93 PF05978.11 KUM63460.1 - 1.7e-15 56.8 2.1 1.7e-15 56.8 1.4 2.5 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 KUM63460.1 - 1.5e-13 50.1 24.8 1.5e-13 50.1 17.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 KUM63460.1 - 0.082 10.9 0.0 0.082 10.9 0.0 2.4 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.19 KUM63460.1 - 0.47 8.9 22.8 0.01 14.4 3.8 2.7 3 0 0 3 3 3 0 Sugar (and other) transporter DUF1769 PF08588.5 KUM63462.1 - 4.5e-17 61.7 0.8 9.2e-17 60.7 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) 3Beta_HSD PF01073.14 KUM63465.1 - 3.9e-20 71.7 0.0 4.7e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KUM63465.1 - 9.8e-06 25.1 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 KUM63465.1 - 0.073 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit PK PF00224.16 KUM63466.1 - 1.5e-171 569.7 2.4 1.8e-171 569.4 1.6 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 KUM63466.1 - 8.4e-32 109.1 0.0 2.4e-31 107.6 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 KUM63466.1 - 0.00012 21.0 0.6 0.00031 19.6 0.4 1.7 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 KUM63466.1 - 0.013 14.3 0.1 0.25 10.1 0.0 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Beta-lactamase PF00144.19 KUM63467.1 - 2e-60 204.5 0.4 2.8e-60 204.1 0.3 1.0 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 KUM63467.1 - 0.0072 15.6 0.2 0.16 11.2 0.0 2.2 2 0 0 2 2 2 1 D-alanyl-D-alanine carboxypeptidase Lipase_GDSL PF00657.17 KUM63469.1 - 2.3e-12 47.2 1.6 2.8e-12 46.9 1.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PY_rept_46 PF09689.5 KUM63470.1 - 0.073 13.4 0.3 1.1 9.5 0.2 2.2 2 0 0 2 2 2 0 Plasmodium yoelii repeat (PY_rept_46) DUF3671 PF12420.3 KUM63470.1 - 1.9 8.4 5.4 9.7 6.2 2.3 2.6 1 1 1 2 2 2 0 Protein of unknown function Arif-1 PF06770.6 KUM63470.1 - 4.6 6.5 9.3 0.94 8.8 3.8 1.8 2 0 0 2 2 2 0 Actin-rearrangement-inducing factor (Arif-1) Iso_dh PF00180.15 KUM63471.1 - 2.9e-97 325.7 0.0 8.5e-97 324.2 0.0 1.6 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ribosomal_S8 PF00410.14 KUM63473.1 - 3.4e-25 88.3 0.0 5.1e-25 87.8 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Kri1 PF05178.7 KUM63474.1 - 0.068 13.4 9.1 0.082 13.1 5.5 1.8 2 0 0 2 2 2 0 KRI1-like family Epimerase PF01370.16 KUM63475.1 - 1.7e-26 93.0 0.0 2.1e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KUM63475.1 - 8.3e-25 87.0 0.0 1e-24 86.7 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KUM63475.1 - 2.4e-15 56.8 0.0 3.1e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM63475.1 - 1.2e-10 41.3 0.0 1.8e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KUM63475.1 - 3.5e-10 40.1 0.0 4.1e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KUM63475.1 - 4.1e-10 39.0 0.0 5.1e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KUM63475.1 - 1.7e-09 37.0 0.0 2.9e-09 36.2 0.0 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KUM63475.1 - 1e-08 34.4 0.0 1.3e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Saccharop_dh PF03435.13 KUM63475.1 - 1.5e-06 27.4 0.0 1.7e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 KUM63475.1 - 4.8e-05 23.3 0.0 7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 TrkA-N domain NmrA PF05368.8 KUM63475.1 - 0.0004 19.7 0.0 0.00086 18.6 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_3 PF03447.11 KUM63475.1 - 0.0012 19.1 0.0 0.0019 18.5 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain adh_short_C2 PF13561.1 KUM63475.1 - 0.0015 18.3 0.0 0.0019 17.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DapB_N PF01113.15 KUM63475.1 - 0.0024 17.7 0.0 0.0045 16.9 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 KUM63475.1 - 0.0051 17.0 0.0 0.0081 16.4 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KUM63475.1 - 0.069 13.5 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Cellulase PF00150.13 KUM63477.1 - 2.7e-44 151.4 0.6 3.9e-44 150.9 0.4 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) EFP PF01132.15 KUM63477.1 - 0.082 12.6 0.1 0.75 9.5 0.0 2.4 2 0 0 2 2 2 0 Elongation factor P (EF-P) OB domain WD40 PF00400.27 KUM63478.1 - 1.9e-22 78.2 32.2 2.3e-09 36.7 0.2 10.9 10 2 0 10 10 10 7 WD domain, G-beta repeat Pil1 PF13805.1 KUM63481.1 - 5.3e-152 504.5 0.4 6.4e-152 504.2 0.3 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 KUM63481.1 - 0.14 11.4 4.5 0.23 10.7 0.5 2.2 1 1 0 2 2 2 0 FAM92 protein XPG_N PF00752.12 KUM63482.1 - 7e-35 119.3 0.6 4e-34 116.9 0.0 2.5 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 KUM63482.1 - 5.4e-25 87.2 0.0 1.8e-24 85.6 0.0 2.0 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 KUM63482.1 - 0.00046 20.3 0.0 0.0012 18.9 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold UIM PF02809.15 KUM63482.1 - 0.0045 16.4 6.3 0.0091 15.4 0.2 3.7 3 0 0 3 3 3 1 Ubiquitin interaction motif XPG_I_2 PF12813.2 KUM63482.1 - 0.0073 15.8 0.0 0.028 13.8 0.0 2.1 1 1 0 1 1 1 1 XPG domain containing Transposase_20 PF02371.11 KUM63482.1 - 0.019 15.0 0.0 0.045 13.8 0.0 1.6 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family SUR7 PF06687.7 KUM63483.1 - 1.3e-47 162.1 13.7 1.5e-47 161.8 9.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF4191 PF13829.1 KUM63483.1 - 0.17 10.9 2.2 0.26 10.3 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) PIP5K PF01504.13 KUM63484.1 - 4.3e-58 196.3 0.0 9.9e-58 195.1 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 KUM63484.1 - 1.3e-24 86.7 0.0 2.1e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 KUM63484.1 - 9.6e-15 54.2 4.1 9.6e-15 54.2 2.8 2.0 2 0 0 2 2 2 1 FYVE zinc finger Aconitase PF00330.15 KUM63485.1 - 1.8e-146 488.3 0.0 5.4e-146 486.7 0.0 1.7 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KUM63485.1 - 5.5e-44 149.4 0.0 9.4e-44 148.6 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain PrpF PF04303.8 KUM63486.1 - 6.2e-81 272.0 0.4 8.8e-81 271.4 0.3 1.1 1 0 0 1 1 1 1 PrpF protein Methyltransf_6 PF03737.10 KUM63486.1 - 2.9e-30 105.1 0.0 4.8e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase Fungal_trans PF04082.13 KUM63487.1 - 1.1e-16 60.4 0.3 2e-16 59.6 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain AA_permease PF00324.16 KUM63488.1 - 1.9e-103 346.3 39.0 2.3e-103 346.1 27.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KUM63488.1 - 2.7e-30 105.2 42.6 5.5e-30 104.2 29.4 1.5 1 1 0 1 1 1 1 Amino acid permease OPA3 PF07047.7 KUM63490.1 - 8.6e-33 112.9 2.9 1.5e-32 112.1 2.0 1.4 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) FSH1 PF03959.8 KUM63491.1 - 0.035 13.5 0.0 0.038 13.4 0.0 1.3 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Ring_hydroxyl_A PF00848.14 KUM63492.1 - 1.8e-39 135.5 3.2 4.1e-39 134.4 2.2 1.5 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 KUM63492.1 - 1.2e-13 50.3 0.0 2.6e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DAO PF01266.19 KUM63493.1 - 9.7e-47 159.5 0.1 5.7e-30 104.4 0.0 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KUM63493.1 - 2.6e-06 27.4 0.0 9.3e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM63493.1 - 3.1e-06 27.1 0.0 6.2e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KUM63493.1 - 1.4e-05 24.1 0.0 0.0049 15.7 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 KUM63493.1 - 5e-05 23.4 0.0 0.00013 22.1 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM63493.1 - 9.3e-05 22.2 0.2 0.17 11.6 0.0 2.8 2 1 1 3 3 3 2 FAD-NAD(P)-binding GIDA PF01134.17 KUM63493.1 - 0.0001 21.3 0.1 0.018 13.9 0.0 2.3 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KUM63493.1 - 0.00028 20.0 0.0 0.0005 19.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KUM63493.1 - 0.014 15.7 0.0 0.029 14.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KUM63493.1 - 0.023 13.8 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 KUM63493.1 - 0.027 14.4 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.7 KUM63493.1 - 0.041 12.8 0.1 0.43 9.4 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein ThiF PF00899.16 KUM63493.1 - 0.052 13.3 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 ThiF family HI0933_like PF03486.9 KUM63493.1 - 0.056 11.9 0.0 3 6.2 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Shikimate_DH PF01488.15 KUM63493.1 - 0.065 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Zn_clus PF00172.13 KUM63495.1 - 3.8e-05 23.5 8.0 7.1e-05 22.6 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 KUM63496.1 - 7.9e-124 413.6 26.5 9e-124 413.4 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM63496.1 - 1.6e-21 76.4 35.5 3.8e-14 52.1 8.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.1 KUM63496.1 - 0.034 14.4 0.2 0.078 13.3 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2530 PF10745.4 KUM63496.1 - 2 8.4 7.0 2.8 7.9 0.4 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Metallophos PF00149.23 KUM63497.1 - 6.8e-11 41.9 0.7 2.4e-09 36.8 0.5 2.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Sugar_tr PF00083.19 KUM63498.1 - 7.8e-09 34.6 3.6 0.00079 18.1 2.2 2.2 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KUM63498.1 - 8.3e-07 28.0 14.1 8e-05 21.5 6.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DAO PF01266.19 KUM63499.1 - 9.6e-52 176.0 0.1 1.1e-51 175.8 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KUM63499.1 - 0.0057 16.3 0.0 0.0099 15.5 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.19 KUM63499.1 - 0.068 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 KUM63499.1 - 0.088 11.8 1.1 1.4 7.9 0.5 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_2 PF03446.10 KUM63499.1 - 0.13 12.1 0.0 0.34 10.7 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Staphylcoagulse PF04022.7 KUM63500.1 - 0.051 12.9 0.4 0.1 11.9 0.0 1.7 2 0 0 2 2 2 0 Staphylocoagulase repeat LysM PF01476.15 KUM63500.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 LysM domain Lipase_GDSL_2 PF13472.1 KUM63501.1 - 1.1e-14 54.9 0.0 1.3e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KUM63501.1 - 1.3e-11 44.7 0.0 1.6e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 KUM63501.1 - 3.2e-05 23.7 0.0 4.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF2817 PF10994.3 KUM63501.1 - 0.13 11.2 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) Acetyltransf_7 PF13508.1 KUM63502.1 - 8.4e-10 38.6 0.0 1.4e-09 37.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KUM63502.1 - 2.8e-08 33.6 0.0 4.7e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KUM63502.1 - 6.7e-05 22.9 0.1 0.00016 21.7 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KUM63502.1 - 0.00048 19.9 0.1 0.0076 16.1 0.1 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain 2-Hacid_dh_C PF02826.14 KUM63503.1 - 7.3e-40 135.9 0.1 1.5e-25 89.3 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KUM63503.1 - 0.00027 20.3 0.0 0.00039 19.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.12 KUM63503.1 - 0.023 15.1 0.0 0.047 14.1 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 KUM63503.1 - 0.033 13.8 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Gp_dh_N PF00044.19 KUM63503.1 - 0.036 14.0 0.2 0.37 10.7 0.2 2.1 1 1 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain MFS_1 PF07690.11 KUM63506.1 - 2.1e-46 158.2 47.7 1.5e-44 152.2 34.9 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM63506.1 - 2.7e-22 78.7 23.7 3.6e-22 78.3 16.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KUM63506.1 - 3.5e-16 58.8 12.4 3.5e-16 58.8 8.6 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter ATG22 PF11700.3 KUM63506.1 - 0.037 12.4 27.3 0.34 9.3 0.4 4.1 3 1 1 4 4 4 0 Vacuole effluxer Atg22 like Epimerase PF01370.16 KUM63507.1 - 2.2e-12 46.9 0.2 2.6e-05 23.7 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KUM63507.1 - 6e-07 28.4 0.0 0.0067 15.1 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KUM63507.1 - 4.9e-05 23.6 0.1 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 KUM63507.1 - 0.00019 20.7 0.1 0.00026 20.3 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 KUM63507.1 - 0.034 13.1 0.2 0.049 12.6 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 KUM63507.1 - 0.063 12.1 0.0 0.12 11.2 0.0 1.6 1 1 0 1 1 1 0 Male sterility protein Dala_Dala_lig_C PF07478.8 KUM63508.1 - 3.9e-13 49.2 0.0 5.5e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.1 KUM63508.1 - 1.9e-12 47.2 0.0 1e-11 44.8 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KUM63508.1 - 0.00011 21.0 0.0 0.0035 16.1 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 KUM63508.1 - 0.00064 19.6 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 KUM63508.1 - 0.0016 17.7 0.0 0.0074 15.5 0.0 1.9 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.17 KUM63508.1 - 0.0017 17.6 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 KUM63508.1 - 0.0028 17.2 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 KUM63508.1 - 0.0035 16.8 0.0 0.0061 16.0 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Pkinase PF00069.20 KUM63509.1 - 4.1e-70 235.8 0.0 1.5e-69 234.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM63509.1 - 3.3e-42 144.3 0.0 4.9e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 KUM63509.1 - 7.3e-08 32.2 0.1 0.0041 17.0 0.0 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 KUM63509.1 - 1e-07 31.2 0.0 2.3e-07 30.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Amidohydro_2 PF04909.9 KUM63510.1 - 8.9e-21 74.6 0.0 1.7e-20 73.7 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase Mito_carr PF00153.22 KUM63511.1 - 2.2e-21 75.3 4.1 9.1e-11 41.3 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Hormone_1 PF00103.15 KUM63511.1 - 0.075 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Somatotropin hormone family Sugar_tr PF00083.19 KUM63512.1 - 1.2e-77 261.4 22.6 1.6e-77 261.0 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM63512.1 - 7.1e-22 77.5 11.2 7.1e-22 77.5 7.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily LPAM_1 PF08139.7 KUM63512.1 - 0.036 14.3 0.0 0.17 12.1 0.0 2.3 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Myosin_head PF00063.16 KUM63513.1 - 6.5e-236 784.6 0.8 9.7e-236 784.0 0.6 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 KUM63513.1 - 7.5e-50 169.0 0.0 1.4e-49 168.1 0.0 1.5 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 KUM63513.1 - 1.7e-12 46.4 0.5 3.6e-12 45.4 0.1 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KUM63513.1 - 6.1e-11 41.7 0.1 1.5e-10 40.4 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KUM63513.1 - 7.8e-09 34.8 0.2 2.5e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain IQ PF00612.22 KUM63513.1 - 0.0039 16.6 7.9 0.48 10.2 0.7 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.1 KUM63513.1 - 0.0076 16.3 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KUM63513.1 - 0.021 13.8 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 KUM63513.1 - 0.058 13.0 0.1 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Hpr_kinase_C PF07475.7 KUM63513.1 - 0.09 12.0 0.6 4.8 6.4 0.1 2.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_17 PF13207.1 KUM63513.1 - 0.097 13.4 0.0 0.3 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain HNH_2 PF13391.1 KUM63515.1 - 5.9e-13 48.3 0.0 1.3e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease MFS_1 PF07690.11 KUM63516.1 - 8e-37 126.7 49.5 9.7e-36 123.1 33.2 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Cation_efflux PF01545.16 KUM63517.1 - 1.2e-40 139.4 0.0 1.5e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 KUM63517.1 - 0.035 13.1 1.9 0.06 12.3 1.3 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1840 PF08895.6 KUM63517.1 - 0.2 11.7 0.4 1.4 8.9 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1840) Glyco_transf_28 PF03033.15 KUM63518.1 - 6.1e-18 64.9 0.0 2.7e-17 62.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KUM63519.1 - 1.1e-06 27.4 0.0 1.7e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KUM63519.1 - 1.3e-05 24.9 0.1 2.7e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.6 KUM63519.1 - 9.7e-05 22.4 0.0 0.00049 20.1 0.0 2.1 2 0 0 2 2 2 1 ATG C terminal domain NOA36 PF06524.7 KUM63519.1 - 0.38 9.9 3.2 0.8 8.9 2.2 1.4 1 0 0 1 1 1 0 NOA36 protein PRONE PF03759.8 KUM63520.1 - 0.0068 14.9 0.0 0.0089 14.6 0.0 1.1 1 0 0 1 1 1 1 PRONE (Plant-specific Rop nucleotide exchanger) CaATP_NAI PF12515.3 KUM63520.1 - 0.14 11.6 0.2 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 Ca2+-ATPase N terminal autoinhibitory domain F-box-like PF12937.2 KUM63521.1 - 0.002 17.8 0.0 0.005 16.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like DUF4636 PF15468.1 KUM63522.1 - 0.084 12.3 0.2 0.13 11.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) Phosphoprotein PF00922.12 KUM63522.1 - 0.4 9.8 2.6 0.49 9.5 1.8 1.1 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein zf-DHHC PF01529.15 KUM63523.1 - 7.4e-30 103.6 6.6 7.4e-30 103.6 4.6 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 KUM63523.1 - 0.0021 17.8 1.8 0.0034 17.1 1.3 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF4095 PF13338.1 KUM63524.1 - 0.0078 16.3 0.6 0.063 13.4 0.1 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4095) Methyltransf_11 PF08241.7 KUM63525.1 - 2e-14 53.8 0.0 4.1e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM63525.1 - 1.3e-13 50.8 0.0 1.8e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM63525.1 - 6.6e-13 48.9 0.0 1.3e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM63525.1 - 4.3e-12 46.6 0.0 6.8e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM63525.1 - 2.7e-11 43.4 0.0 4.4e-11 42.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM63525.1 - 9.2e-09 35.5 0.0 1.8e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KUM63525.1 - 8.7e-08 31.7 0.0 1.3e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KUM63525.1 - 2e-06 27.8 0.0 3.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 KUM63525.1 - 1.6e-05 24.1 0.0 2.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 KUM63525.1 - 2.4e-05 23.5 0.0 3.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.6 KUM63525.1 - 0.00011 21.6 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.6 KUM63525.1 - 0.00018 20.3 0.0 0.00035 19.3 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.8 KUM63525.1 - 0.00035 19.8 0.0 0.00051 19.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 KUM63525.1 - 0.0014 18.2 0.0 0.0035 16.8 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DREV PF05219.7 KUM63525.1 - 0.0024 16.7 0.0 0.0038 16.1 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase CMAS PF02353.15 KUM63525.1 - 0.0042 16.1 0.0 0.006 15.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Pox_MCEL PF03291.11 KUM63525.1 - 0.0058 15.5 0.0 0.0091 14.8 0.0 1.4 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_32 PF13679.1 KUM63525.1 - 0.0094 15.6 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KUM63525.1 - 0.053 12.5 0.0 0.087 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase MetW PF07021.7 KUM63525.1 - 0.073 12.4 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TehB PF03848.9 KUM63525.1 - 0.14 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB HATPase_c PF02518.21 KUM63526.1 - 4.1e-14 52.2 0.3 1.5e-13 50.4 0.1 2.1 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KUM63526.1 - 3.2e-12 46.2 0.1 8.8e-12 44.8 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 KUM63526.1 - 6.7e-09 35.2 0.0 1.5e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain DUF1295 PF06966.7 KUM63527.1 - 2.7e-34 118.4 0.0 3.9e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 KUM63527.1 - 9.1e-05 22.5 0.0 0.00021 21.3 0.0 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase Steroid_dh PF02544.11 KUM63527.1 - 0.0026 17.5 0.0 0.005 16.6 0.0 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ERG4_ERG24 PF01222.12 KUM63527.1 - 0.0066 15.0 0.0 0.01 14.4 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.9 KUM63527.1 - 0.0072 16.5 0.0 0.022 14.9 0.0 1.8 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family p450 PF00067.17 KUM63529.1 - 3.3e-73 246.7 0.0 4.3e-73 246.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 KUM63529.1 - 3.1e-31 108.5 0.0 8.6e-31 107.0 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.20 KUM63529.1 - 1.8e-17 63.6 0.0 3.1e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KUM63529.1 - 6.1e-12 46.0 0.0 1.2e-11 45.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KUM63529.1 - 0.0015 18.4 0.0 0.021 14.7 0.0 2.7 4 0 0 4 4 4 1 Ferric reductase NAD binding domain HTH_20 PF12840.2 KUM63529.1 - 0.31 10.8 1.3 4.5 7.1 0.0 3.5 4 0 0 4 4 4 0 Helix-turn-helix domain p450 PF00067.17 KUM63530.1 - 2e-83 280.5 0.0 2.6e-83 280.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 KUM63530.1 - 8.4e-33 113.6 0.0 1.3e-32 112.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KUM63530.1 - 4.6e-23 81.7 0.0 2.9e-22 79.1 0.0 2.3 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 KUM63530.1 - 2.7e-11 44.0 0.0 6.6e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KUM63530.1 - 0.00055 19.9 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain ABC2_membrane PF01061.19 KUM63531.1 - 1.7e-86 288.7 46.3 4.1e-47 160.0 11.8 2.9 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 KUM63531.1 - 2.7e-34 116.9 7.0 3.2e-29 100.6 0.0 3.8 4 0 0 4 4 3 2 CDR ABC transporter ABC_tran PF00005.22 KUM63531.1 - 8.5e-32 110.3 0.0 1.1e-15 58.1 0.0 3.4 3 1 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.1 KUM63531.1 - 5.6e-16 58.3 0.1 1.2e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KUM63531.1 - 1.4e-08 34.3 0.1 0.00022 20.6 0.0 2.7 3 0 0 3 3 2 2 AAA domain ABC2_membrane_3 PF12698.2 KUM63531.1 - 1.8e-08 33.8 34.6 0.00011 21.3 8.2 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_33 PF13671.1 KUM63531.1 - 9.5e-07 28.7 0.2 0.0026 17.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KUM63531.1 - 2.3e-06 27.7 0.8 0.0029 17.6 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 KUM63531.1 - 8e-06 25.1 0.2 0.0003 20.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 KUM63531.1 - 0.00017 21.0 1.3 0.0072 15.7 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 KUM63531.1 - 0.00026 21.1 0.2 0.12 12.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KUM63531.1 - 0.00026 20.4 0.6 0.39 10.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_19 PF13245.1 KUM63531.1 - 0.00045 19.9 2.1 0.47 10.2 0.2 2.9 2 0 0 2 2 2 2 Part of AAA domain AAA_18 PF13238.1 KUM63531.1 - 0.00096 19.4 0.2 0.082 13.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KUM63531.1 - 0.0013 17.9 0.0 0.25 10.5 0.0 3.6 4 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 KUM63531.1 - 0.0017 17.8 2.1 1.1 8.6 0.1 3.4 4 1 0 4 4 4 2 AAA-like domain AAA_17 PF13207.1 KUM63531.1 - 0.0027 18.5 0.0 0.23 12.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KUM63531.1 - 0.0056 16.8 0.6 5 7.3 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KUM63531.1 - 0.0063 16.2 0.1 1.1 8.9 0.0 2.6 2 1 0 2 2 2 1 Archaeal ATPase T2SE PF00437.15 KUM63531.1 - 0.0064 15.4 0.2 2.9 6.7 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein NACHT PF05729.7 KUM63531.1 - 0.0065 16.1 1.2 0.88 9.2 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.1 KUM63531.1 - 0.029 14.3 1.7 0.18 11.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KUM63531.1 - 0.031 14.0 0.6 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 KUM63531.1 - 0.036 14.0 0.2 0.82 9.6 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.1 KUM63531.1 - 0.077 12.5 0.8 1.9 8.0 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KUM63531.1 - 0.098 12.5 0.0 2.9 7.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KUM63531.1 - 0.11 12.6 0.1 12 6.1 0.0 2.9 2 0 0 2 2 2 0 RNA helicase Viral_helicase1 PF01443.13 KUM63531.1 - 0.17 11.4 0.1 4.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 KUM63531.1 - 0.2 11.3 2.5 1.4 8.5 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_21 PF13304.1 KUM63531.1 - 0.21 11.5 0.4 4 7.3 0.3 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KUM63531.1 - 0.33 10.0 1.9 2.9 6.9 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin RuvB_N PF05496.7 KUM63531.1 - 0.83 8.6 2.3 15 4.5 0.2 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus SMC_N PF02463.14 KUM63532.1 - 5.4e-78 261.2 3.6 1.6e-77 259.6 2.5 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KUM63532.1 - 7.9e-28 96.8 0.1 3.5e-27 94.7 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KUM63532.1 - 7.9e-12 45.7 6.5 4.8e-05 23.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KUM63532.1 - 0.00013 21.3 0.0 0.00029 20.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Snapin_Pallidin PF14712.1 KUM63532.1 - 0.002 18.3 3.7 0.002 18.3 2.6 7.7 5 1 1 7 7 7 2 Snapin/Pallidin Tropomyosin_1 PF12718.2 KUM63532.1 - 0.0022 17.8 12.4 0.0022 17.8 8.6 7.7 2 2 4 7 7 6 3 Tropomyosin like ATG16 PF08614.6 KUM63532.1 - 0.0053 16.5 4.8 0.0053 16.5 3.4 7.7 3 2 5 8 8 7 2 Autophagy protein 16 (ATG16) DUF4140 PF13600.1 KUM63532.1 - 0.0058 17.0 4.0 0.0058 17.0 2.7 10.3 6 3 6 12 12 11 2 N-terminal domain of unknown function (DUF4140) Reo_sigmaC PF04582.7 KUM63532.1 - 0.12 11.5 24.3 0.011 14.9 0.8 4.9 2 2 2 5 5 5 0 Reovirus sigma C capsid protein Bacillus_HBL PF05791.6 KUM63532.1 - 4.8 6.5 51.0 0.1 11.9 2.0 6.4 5 1 1 6 6 6 0 Bacillus haemolytic enterotoxin (HBL) DUF3584 PF12128.3 KUM63532.1 - 5.2 4.2 89.3 0.0011 16.4 29.3 2.6 2 1 0 2 2 1 0 Protein of unknown function (DUF3584) FAD_binding_4 PF01565.18 KUM63534.1 - 4.1e-16 58.7 0.1 6e-16 58.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.9 KUM63534.1 - 5.2e-05 22.9 0.7 5.2e-05 22.9 0.5 1.9 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase CUE PF02845.11 KUM63535.1 - 3.1e-06 26.5 0.1 5.6e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 CUE domain FA_desaturase PF00487.19 KUM63536.1 - 1.8e-35 122.6 26.2 2.4e-35 122.2 18.2 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KUM63536.1 - 3.9e-12 45.7 0.0 8.2e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Unstab_antitox PF09720.5 KUM63536.1 - 0.084 12.5 1.1 0.15 11.7 0.1 1.9 2 0 0 2 2 2 0 Putative addiction module component PGM_PMM_I PF02878.11 KUM63537.1 - 2.4e-37 127.4 0.0 4.9e-37 126.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KUM63537.1 - 1.1e-23 83.5 0.0 2.9e-23 82.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 KUM63537.1 - 1e-13 51.2 0.2 1.8e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 KUM63537.1 - 7.7e-09 35.4 0.0 2.6e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Pkinase PF00069.20 KUM63538.1 - 9.2e-13 47.9 0.0 1.4e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KUM63538.1 - 3.6e-08 33.4 0.6 1.8e-07 31.1 0.4 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KUM63538.1 - 7e-06 25.2 0.0 1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KUM63538.1 - 5.8e-05 22.2 0.1 8.3e-05 21.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KUM63538.1 - 0.00015 21.1 0.0 0.00025 20.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 KUM63538.1 - 0.024 14.2 0.0 0.03 13.9 0.0 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase DDE_Tnp_1_2 PF13586.1 KUM63538.1 - 0.053 13.7 0.0 3.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain zf-C2H2_jaz PF12171.3 KUM63539.1 - 2.1e-45 151.8 29.4 2.6e-06 27.3 0.0 8.4 8 0 0 8 8 8 8 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KUM63539.1 - 2.9e-41 138.4 30.9 3.6e-06 26.9 0.0 8.9 9 0 0 9 9 9 8 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KUM63539.1 - 8.4e-22 76.1 34.7 0.026 14.8 0.3 8.6 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KUM63539.1 - 1.7e-20 71.7 34.2 0.00064 19.8 0.1 8.4 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KUM63539.1 - 5.9e-12 45.0 37.5 0.43 10.5 0.3 9.0 9 0 0 9 9 9 7 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KUM63539.1 - 1.6e-09 37.5 27.3 3.5 8.0 0.0 8.5 8 0 0 8 8 8 5 Zinc-finger double domain zf-C2H2_2 PF12756.2 KUM63539.1 - 1e-07 31.9 25.6 0.44 10.6 0.0 8.2 2 1 7 9 9 9 4 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 KUM63539.1 - 2.6e-07 30.1 23.2 0.27 10.9 0.0 8.1 8 0 0 8 8 8 3 zinc-finger of a C2HC-type zf-met2 PF12907.2 KUM63539.1 - 4.7e-05 23.2 18.8 11 6.0 0.0 7.8 8 0 0 8 8 8 0 Zinc-binding LIM PF00412.17 KUM63539.1 - 0.00015 21.7 21.3 0.88 9.6 0.5 4.8 3 1 0 4 4 4 3 LIM domain Ribosomal_L31 PF01197.13 KUM63539.1 - 0.00046 20.1 10.4 7.8 6.5 0.1 6.4 2 1 3 5 5 5 1 Ribosomal protein L31 HTH_5 PF01022.15 KUM63539.1 - 0.0018 17.9 7.1 1 9.0 0.0 4.6 6 0 0 6 6 6 2 Bacterial regulatory protein, arsR family zf-DBF PF07535.7 KUM63539.1 - 0.012 15.2 15.8 0.19 11.4 0.2 6.6 6 1 1 7 7 7 0 DBF zinc finger SprT-like PF10263.4 KUM63539.1 - 0.014 15.0 11.5 8.1 6.0 0.2 3.8 1 1 1 2 2 2 0 SprT-like family C1_4 PF07975.7 KUM63539.1 - 0.046 13.7 30.0 3.3 7.7 0.6 6.3 1 1 6 7 7 7 0 TFIIH C1-like domain Lant_dehyd_C PF04738.8 KUM63539.1 - 0.15 10.2 0.0 0.28 9.3 0.0 1.4 1 0 0 1 1 1 0 Lantibiotic dehydratase, C terminus PLATZ PF04640.9 KUM63539.1 - 1.1 9.5 18.2 31 4.8 0.0 6.8 1 1 7 8 8 8 0 PLATZ transcription factor zf-CCCH PF00642.19 KUM63543.1 - 4e-07 29.5 2.8 8.2e-07 28.5 2.0 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KUM63543.1 - 0.095 12.7 4.9 0.23 11.4 3.4 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Ribosomal_S10 PF00338.17 KUM63544.1 - 5.6e-28 96.6 0.6 6.7e-28 96.3 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e zf-RING_2 PF13639.1 KUM63545.1 - 3.1e-07 30.1 9.1 5.3e-07 29.3 6.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KUM63545.1 - 1.1e-05 25.3 9.1 1.8e-05 24.6 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KUM63545.1 - 1.5e-05 24.5 9.1 2.4e-05 23.8 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KUM63545.1 - 7.1e-05 22.3 5.2 0.00011 21.7 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KUM63545.1 - 0.0013 18.7 7.8 0.0037 17.3 5.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-MIZ PF02891.15 KUM63545.1 - 0.28 10.7 7.8 0.48 9.9 5.4 1.3 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_5 PF14634.1 KUM63545.1 - 2.6 7.8 7.0 4.5 7.0 4.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Drc1-Sld2 PF11719.3 KUM63546.1 - 2.1e-115 386.2 26.5 2.4e-115 386.0 18.4 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein GMC_oxred_N PF00732.14 KUM63547.1 - 7e-81 271.6 0.0 1e-80 271.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KUM63547.1 - 1.5e-29 103.1 0.0 2.5e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KUM63547.1 - 0.0015 18.5 0.0 0.0044 17.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KUM63547.1 - 0.0028 16.5 0.1 0.0047 15.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KUM63547.1 - 0.012 14.5 0.1 0.026 13.4 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 KUM63547.1 - 0.028 13.2 0.2 0.062 12.1 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain DUF2410 PF10307.4 KUM63548.1 - 3.8e-81 271.2 0.0 5.1e-81 270.7 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) Suc_Fer-like PF06999.7 KUM63549.1 - 4.6e-49 167.5 0.0 5.3e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Fungal_trans PF04082.13 KUM63550.1 - 3.4e-10 39.2 1.6 3.4e-10 39.2 1.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM63550.1 - 3.6e-09 36.3 7.8 7.2e-09 35.4 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_16 PF00722.16 KUM63552.1 - 5.3e-40 136.6 5.8 8.7e-40 135.9 4.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 ELYS PF13934.1 KUM63553.1 - 2.2e-77 259.8 0.2 2.7e-77 259.5 0.1 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly Glyco_hydro_43 PF04616.9 KUM63554.1 - 5e-35 120.9 1.7 6.5e-35 120.5 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 adh_short_C2 PF13561.1 KUM63555.1 - 2.6e-25 89.5 0.4 3e-25 89.3 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KUM63555.1 - 1.7e-22 80.1 5.6 2.1e-22 79.8 3.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM63555.1 - 4.3e-10 39.5 3.4 6e-10 39.0 2.4 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KUM63555.1 - 0.0099 15.5 0.2 0.017 14.8 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KUM63555.1 - 0.036 13.2 0.1 0.054 12.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fungal_trans PF04082.13 KUM63556.1 - 1.8e-12 46.6 0.0 3.3e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FMO-like PF00743.14 KUM63557.1 - 3.1e-22 78.4 0.5 5.2e-10 38.1 0.0 4.0 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KUM63557.1 - 8e-16 58.6 0.6 7.8e-15 55.4 0.4 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM63557.1 - 8e-08 32.1 0.8 0.00025 20.8 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KUM63557.1 - 1.2e-06 28.5 0.0 0.0028 17.5 0.1 3.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM63557.1 - 4.4e-06 26.6 0.0 1.3e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KUM63557.1 - 0.065 12.1 0.4 9.7 4.9 0.3 2.6 2 1 0 3 3 3 0 FAD dependent oxidoreductase Semialdhyde_dh PF01118.19 KUM63557.1 - 0.092 13.0 0.0 0.56 10.5 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DUF371 PF04027.8 KUM63557.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF371) Thi4 PF01946.12 KUM63557.1 - 0.13 11.3 0.1 0.37 9.8 0.1 1.8 1 0 0 1 1 1 0 Thi4 family MAM33 PF02330.11 KUM63558.1 - 2e-34 119.1 6.0 2.5e-34 118.8 4.1 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Kri1 PF05178.7 KUM63558.1 - 0.6 10.4 6.6 0.3 11.3 2.5 1.9 2 0 0 2 2 2 0 KRI1-like family DNA_primase_S PF01896.14 KUM63559.1 - 3.2e-53 179.4 0.0 5.2e-53 178.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit DUF1236 PF06823.7 KUM63560.1 - 0.19 11.5 11.0 0.68 9.7 1.7 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1236) DUF452 PF04301.8 KUM63560.1 - 0.56 9.4 2.2 28 3.9 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF452) XPG_I PF00867.13 KUM63561.1 - 1.5e-26 92.3 0.1 2.7e-26 91.4 0.1 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KUM63561.1 - 1.6e-23 82.8 0.0 1.1e-22 80.1 0.0 2.2 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.2 KUM63561.1 - 0.0003 20.3 0.0 0.00053 19.5 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing DUF2962 PF11176.3 KUM63562.1 - 9.8e-51 171.3 5.0 1.1e-50 171.2 3.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) DUF505 PF04458.7 KUM63562.1 - 0.046 11.8 0.1 0.066 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF505) Cauli_AT PF03233.8 KUM63562.1 - 0.048 13.3 0.6 0.068 12.8 0.4 1.2 1 0 0 1 1 1 0 Aphid transmission protein DUF2414 PF10309.4 KUM63562.1 - 0.064 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) Penicillinase_R PF03965.11 KUM63562.1 - 0.14 12.2 0.6 0.33 11.0 0.1 1.8 2 0 0 2 2 2 0 Penicillinase repressor HTH_32 PF13565.1 KUM63562.1 - 0.53 11.1 5.3 2.3 9.0 0.8 2.3 1 1 1 2 2 2 0 Homeodomain-like domain Fig1 PF12351.3 KUM63564.1 - 2.7e-60 203.3 4.8 2.7e-60 203.3 3.3 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 KUM63564.1 - 1.2e-08 34.8 4.6 1.9e-08 34.1 3.2 1.3 1 1 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 KUM63564.1 - 0.00014 20.8 3.7 0.00014 20.8 2.6 1.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) DUF3733 PF12534.3 KUM63564.1 - 6.5 6.1 6.2 5.4 6.3 0.3 2.7 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 adh_short PF00106.20 KUM63565.1 - 7e-35 120.4 0.0 8.5e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM63565.1 - 2.3e-15 57.0 0.1 3e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM63565.1 - 7e-14 51.8 0.0 1e-13 51.3 0.0 1.3 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KUM63565.1 - 0.002 17.0 0.1 0.0028 16.6 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KUM63565.1 - 0.018 14.4 0.0 0.025 14.0 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KUM63565.1 - 0.023 14.4 1.3 0.083 12.6 0.1 2.3 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF258 PF03193.11 KUM63565.1 - 0.13 11.4 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SOG2 PF10428.4 KUM63566.1 - 1.1 7.8 6.3 1.2 7.6 4.4 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein DUF515 PF04415.7 KUM63566.1 - 3.4 5.8 11.6 4.3 5.4 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) MIT PF04212.13 KUM63567.1 - 0.0001 22.1 0.1 0.00017 21.3 0.1 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_7 PF13176.1 KUM63567.1 - 0.0072 16.0 0.0 0.024 14.4 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF1189 PF06691.6 KUM63567.1 - 0.097 11.9 0.0 2.3 7.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1189) TPR_12 PF13424.1 KUM63567.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 KUM63567.1 - 0.16 11.6 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat SnoaL_4 PF13577.1 KUM63568.1 - 9.9e-08 31.9 0.3 1.5e-07 31.3 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.2 KUM63568.1 - 0.0011 19.3 0.4 0.0017 18.7 0.3 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 KUM63568.1 - 0.091 12.8 0.8 0.15 12.1 0.5 1.3 1 0 0 1 1 1 0 SnoaL-like domain DUF4440 PF14534.1 KUM63568.1 - 0.1 12.8 0.3 0.24 11.6 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) MFS_1 PF07690.11 KUM63569.1 - 9.4e-34 116.6 30.0 1.4e-33 116.1 20.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Ras PF00071.17 KUM63573.1 - 5.1e-54 182.0 1.2 5.8e-53 178.5 0.9 1.9 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KUM63573.1 - 9.4e-16 58.3 0.0 1.7e-15 57.5 0.0 1.4 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KUM63573.1 - 8.6e-08 31.8 0.0 2.1e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 KUM63573.1 - 2e-06 27.1 0.0 0.00022 20.5 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family FeoB_N PF02421.13 KUM63573.1 - 0.0063 15.8 0.1 0.026 13.7 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B ATP_bind_1 PF03029.12 KUM63573.1 - 0.064 12.7 0.2 2.1 7.8 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.12 KUM63573.1 - 0.074 12.4 0.0 0.75 9.1 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF258 PF03193.11 KUM63573.1 - 0.088 11.9 0.1 0.23 10.6 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 CbiA PF01656.18 KUM63573.1 - 0.09 12.1 0.2 1.5 8.2 0.0 2.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_14 PF13173.1 KUM63573.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KUM63573.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase MoCF_biosynth PF00994.19 KUM63574.1 - 5.9e-37 126.2 0.0 9.3e-37 125.6 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain Nuf2 PF03800.9 KUM63576.1 - 2.3e-45 154.1 0.2 2.3e-45 154.1 0.1 2.2 2 0 0 2 2 2 1 Nuf2 family MHYT PF03707.11 KUM63577.1 - 1.1e-08 34.9 25.1 6.2e-06 26.2 0.3 5.6 5 1 0 5 5 5 2 Bacterial signalling protein N terminal repeat UBA PF00627.26 KUM63577.1 - 0.1 12.4 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 UBA/TS-N domain DUF1772 PF08592.6 KUM63577.1 - 2.6 7.7 16.9 1.6 8.4 0.3 3.8 1 1 3 4 4 4 0 Domain of unknown function (DUF1772) DUF775 PF05603.7 KUM63578.1 - 3.2e-58 196.6 0.0 3.6e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Thioredoxin PF00085.15 KUM63579.1 - 3.2e-30 103.8 0.2 3.9e-30 103.5 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KUM63579.1 - 2.4e-07 30.9 0.1 2.2e-06 27.8 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KUM63579.1 - 3.6e-06 26.9 0.0 6.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 KUM63579.1 - 1.2e-05 25.2 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 KUM63579.1 - 1.3e-05 24.7 0.0 1.7e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 KUM63579.1 - 1.5e-05 24.6 0.0 1.8e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KUM63579.1 - 0.00094 18.7 0.2 0.0016 17.9 0.2 1.4 1 1 0 1 1 1 1 Redoxin Cpl-7 PF08230.6 KUM63579.1 - 0.03 14.0 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Cpl-7 lysozyme C-terminal domain Glutaredoxin PF00462.19 KUM63579.1 - 0.048 13.6 0.1 0.13 12.3 0.0 1.7 1 1 0 1 1 1 0 Glutaredoxin LeuA_dimer PF08502.5 KUM63579.1 - 0.1 12.3 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 LeuA allosteric (dimerisation) domain Acetyltransf_4 PF13420.1 KUM63580.1 - 2e-08 34.3 0.0 2.6e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KUM63580.1 - 1.6e-06 28.3 0.0 2.2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KUM63580.1 - 0.0026 17.6 0.1 0.0056 16.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Pkinase_Tyr PF07714.12 KUM63581.1 - 0.00017 20.7 0.1 0.0013 17.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KUM63581.1 - 0.00024 20.3 0.0 0.00079 18.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Fe-S_assembly PF04384.8 KUM63581.1 - 0.013 15.8 0.1 2.4 8.5 0.0 2.5 2 0 0 2 2 2 0 Iron-sulphur cluster assembly TPR_12 PF13424.1 KUM63582.1 - 8.7e-73 240.2 45.6 2.6e-12 46.4 0.1 8.2 2 2 7 10 10 10 9 Tetratricopeptide repeat Pkinase PF00069.20 KUM63582.1 - 1e-51 175.6 0.0 1.5e-51 175.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TPR_10 PF13374.1 KUM63582.1 - 1.6e-49 164.4 28.8 0.00028 20.7 0.5 12.6 12 0 0 12 12 12 11 Tetratricopeptide repeat Pkinase_Tyr PF07714.12 KUM63582.1 - 5.1e-29 101.1 0.0 7.8e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_1 PF00515.23 KUM63582.1 - 1e-12 47.0 10.2 0.42 10.3 0.0 9.4 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_2 PF07719.12 KUM63582.1 - 7.9e-12 44.1 17.2 0.57 10.2 0.1 10.3 11 0 0 11 11 10 3 Tetratricopeptide repeat Kinase-like PF14531.1 KUM63582.1 - 1.9e-10 40.1 0.0 3.4e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like TPR_11 PF13414.1 KUM63582.1 - 1.2e-09 37.7 17.4 0.011 15.4 0.5 8.0 6 2 2 8 8 8 3 TPR repeat Apc3 PF12895.2 KUM63582.1 - 3.9e-07 30.1 14.4 0.00062 19.8 0.1 5.5 3 2 3 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF630 PF04783.7 KUM63582.1 - 1e-06 28.5 12.1 7.3 6.5 0.0 8.5 9 0 0 9 9 8 0 Protein of unknown function (DUF630) BTAD PF03704.12 KUM63582.1 - 2.5e-06 27.8 22.4 2.8 8.2 0.4 8.4 4 1 4 8 8 8 1 Bacterial transcriptional activator domain TPR_4 PF07721.9 KUM63582.1 - 2.9e-05 24.0 7.6 1.5 9.4 0.2 7.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 KUM63582.1 - 9.8e-05 22.6 21.4 7.4 7.5 0.3 8.5 9 1 0 9 9 8 0 Tetratricopeptide repeat TPR_19 PF14559.1 KUM63582.1 - 0.00038 20.7 21.3 0.011 16.0 1.2 6.5 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 KUM63582.1 - 0.00046 19.7 16.1 1.8 8.5 0.1 7.2 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 KUM63582.1 - 0.0012 19.4 18.9 0.023 15.3 1.4 5.3 6 1 1 7 7 5 2 Tetratricopeptide repeat TPR_21 PF09976.4 KUM63582.1 - 0.011 15.6 5.4 6.8 6.6 0.0 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat RVT_thumb PF06817.9 KUM63582.1 - 0.013 15.1 0.0 17 5.0 0.0 4.5 5 0 0 5 5 5 0 Reverse transcriptase thumb domain HTH_43 PF09904.4 KUM63582.1 - 0.013 15.3 0.1 3.6 7.4 0.0 3.7 4 1 1 5 5 4 0 Winged helix-turn helix Pox_ser-thr_kin PF05445.6 KUM63582.1 - 0.098 11.4 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TPR_17 PF13431.1 KUM63582.1 - 0.22 11.8 9.7 34 4.9 0.0 7.3 9 0 0 9 9 8 0 Tetratricopeptide repeat IF-2B PF01008.12 KUM63583.1 - 6.1e-49 166.5 0.0 7.6e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family OPT PF03169.10 KUM63585.1 - 8.3e-180 599.2 45.2 9.5e-180 599.0 31.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein NUDIX PF00293.23 KUM63587.1 - 4.1e-09 36.1 0.0 7.4e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain 2OG-FeII_Oxy PF03171.15 KUM63588.1 - 3e-15 56.3 0.0 5.2e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KUM63588.1 - 8.9e-12 45.5 0.0 1.4e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal UPF0086 PF01868.11 KUM63589.1 - 1e-30 105.2 0.1 1.6e-30 104.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Cofilin_ADF PF00241.15 KUM63590.1 - 2.3e-12 46.9 0.0 2.6e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DZR PF12773.2 KUM63591.1 - 3.9 7.3 33.2 5.8 6.8 1.8 3.6 2 2 1 3 3 3 0 Double zinc ribbon PAXNEB PF05625.6 KUM63592.1 - 3.9e-126 420.7 0.0 4.3e-126 420.6 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein RNA_pol_Rpb8 PF03870.10 KUM63593.1 - 3.8e-39 134.0 0.0 4.3e-39 133.8 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 tRNA_int_endo PF01974.12 KUM63594.1 - 6.9e-15 54.6 0.0 1.4e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Adaptin_N PF01602.15 KUM63596.1 - 1.2e-99 334.0 0.0 2.4e-99 333.0 0.0 1.4 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KUM63596.1 - 1.1e-10 41.6 0.2 0.00039 20.6 0.0 4.4 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.17 KUM63596.1 - 2e-08 33.6 0.2 0.067 13.2 0.0 5.9 7 0 0 7 7 7 2 HEAT repeat Cohesin_HEAT PF12765.2 KUM63596.1 - 0.001 18.9 0.2 0.055 13.4 0.0 2.7 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.1 KUM63596.1 - 0.0061 17.0 1.8 5 7.7 0.0 4.4 5 0 0 5 5 5 1 HEAT-like repeat TT_ORF2 PF02957.10 KUM63596.1 - 7.5 7.2 20.4 11 6.6 2.6 2.9 2 0 0 2 2 2 0 TT viral ORF2 Amidohydro_1 PF01979.15 KUM63597.1 - 3.9e-20 72.7 0.1 5.2e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KUM63597.1 - 2.5e-14 52.8 0.0 9.8e-14 50.9 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 KUM63597.1 - 1.8e-06 28.1 0.0 3e-06 27.4 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KUM63597.1 - 0.0049 16.1 1.3 0.22 10.6 0.1 2.4 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.15 KUM63598.1 - 3.6e-06 26.8 0.0 4e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KUM63598.1 - 2.9e-05 23.4 0.0 3.5e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KUM63598.1 - 4.6e-05 23.5 0.0 6e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Metallophos PF00149.23 KUM63599.1 - 7.2e-41 139.7 0.4 9.2e-41 139.4 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rho_GDI PF02115.12 KUM63600.1 - 9.1e-60 201.4 0.6 9.9e-60 201.3 0.4 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor KilA-N PF04383.8 KUM63601.1 - 0.00095 18.7 3.4 0.038 13.6 0.0 3.0 2 1 1 3 3 3 2 KilA-N domain DUF2011 PF09428.5 KUM63601.1 - 0.0012 18.7 9.8 0.0012 18.7 6.8 2.4 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF2011) GET2 PF08690.5 KUM63601.1 - 0.24 10.5 8.1 0.35 10.0 5.6 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Asp-B-Hydro_N PF05279.6 KUM63601.1 - 0.77 9.5 29.8 1.6 8.5 20.7 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region FimP PF09766.4 KUM63601.1 - 2.3 7.2 14.4 3.4 6.6 3.3 2.1 2 0 0 2 2 2 0 Fms-interacting protein NmrA PF05368.8 KUM63602.1 - 1.4e-32 112.8 0.0 1.8e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KUM63602.1 - 7.7e-17 61.8 0.0 1e-16 61.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KUM63602.1 - 1.1e-05 24.2 0.0 9.6e-05 21.2 0.0 2.1 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KUM63602.1 - 0.0004 19.9 0.0 0.0082 15.5 0.0 2.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KUM63602.1 - 0.00046 19.1 0.0 0.0024 16.8 0.0 2.1 2 1 0 2 2 2 1 Male sterility protein KR PF08659.5 KUM63602.1 - 0.0013 18.4 0.0 0.0089 15.7 0.0 2.0 2 0 0 2 2 2 1 KR domain Semialdhyde_dh PF01118.19 KUM63602.1 - 0.0018 18.5 0.0 0.0052 17.0 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 KUM63602.1 - 0.0063 16.4 0.0 0.019 14.8 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase DapB_N PF01113.15 KUM63602.1 - 0.024 14.5 0.0 0.051 13.4 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 KUM63602.1 - 0.062 13.8 0.2 0.45 11.0 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 KUM63602.1 - 0.084 13.3 0.3 0.23 11.9 0.1 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Methyltransf_31 PF13847.1 KUM63603.1 - 1.9e-08 34.0 0.0 2.6e-08 33.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KUM63603.1 - 3.6e-07 30.2 0.0 6.9e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KUM63603.1 - 9.7e-06 24.8 0.0 1.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KUM63603.1 - 1.1e-05 25.6 0.1 2.1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KUM63603.1 - 2e-05 24.0 0.1 3.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 KUM63603.1 - 4.2e-05 23.9 0.1 7.6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM63603.1 - 6.2e-05 23.4 0.0 0.00012 22.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM63603.1 - 0.0015 19.1 0.0 0.0021 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 KUM63603.1 - 0.026 13.5 0.1 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_32 PF13679.1 KUM63603.1 - 0.058 13.0 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Clp1 PF06807.9 KUM63604.1 - 9.5e-17 61.4 0.0 2.5e-10 40.4 0.0 2.2 2 0 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 KUM63604.1 - 4.4e-05 23.2 0.0 7.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KUM63604.1 - 0.0002 21.2 0.0 0.00091 19.1 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KUM63604.1 - 0.00034 20.2 0.0 0.0025 17.3 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_35 PF14516.1 KUM63604.1 - 0.024 13.2 0.0 0.036 12.6 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain SRP54 PF00448.17 KUM63604.1 - 0.12 11.7 0.0 15 4.9 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_16 PF13191.1 KUM63604.1 - 0.18 11.7 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Sgf11 PF08209.6 KUM63605.1 - 0.22 10.8 4.7 1.1 8.6 0.2 3.2 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) DUF1777 PF08648.7 KUM63606.1 - 2e-24 86.3 13.9 3.1e-24 85.7 9.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) CENP-N PF05238.8 KUM63606.1 - 0.38 9.7 2.1 0.55 9.2 1.5 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like DAO PF01266.19 KUM63607.1 - 2.8e-62 210.7 0.3 3.5e-62 210.4 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KUM63607.1 - 1.2e-06 28.4 0.3 2.6e-06 27.3 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KUM63607.1 - 2.6e-05 23.0 0.3 0.0011 17.6 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 KUM63607.1 - 0.00014 21.8 1.4 0.54 10.0 0.1 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KUM63607.1 - 0.00087 18.2 0.5 0.33 9.7 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 KUM63607.1 - 0.0017 17.4 0.1 0.0031 16.6 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 KUM63607.1 - 0.0024 17.6 0.5 0.035 13.8 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 KUM63607.1 - 0.006 16.9 1.2 0.013 15.9 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 KUM63607.1 - 0.011 13.9 0.0 0.29 9.2 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_oxidored PF12831.2 KUM63607.1 - 0.016 14.3 0.6 0.19 10.7 0.4 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 KUM63607.1 - 0.069 12.0 0.8 6.6 5.4 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KUM63607.1 - 0.077 13.0 0.1 3.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Strep_67kDa_ant PF06100.6 KUM63607.1 - 0.13 10.5 0.1 0.22 9.8 0.1 1.3 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Sugar_tr PF00083.19 KUM63608.1 - 3.6e-82 276.3 19.7 4.2e-82 276.1 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM63608.1 - 1.6e-17 63.2 26.9 4.4e-17 61.8 15.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KUM63608.1 - 2.9e-06 25.9 21.9 0.00034 19.1 1.4 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein Alpha-amylase PF00128.19 KUM63609.1 - 8e-83 278.4 0.8 8e-83 278.4 0.6 1.8 2 1 0 2 2 2 1 Alpha amylase, catalytic domain DUF3459 PF11941.3 KUM63609.1 - 0.049 13.7 0.0 0.098 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) Chlorophyllase2 PF12740.2 KUM63609.1 - 0.11 11.3 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme DeoC PF01791.4 KUM63609.1 - 0.19 10.9 0.0 0.36 10.0 0.0 1.3 1 0 0 1 1 1 0 DeoC/LacD family aldolase Elong_Iki1 PF10483.4 KUM63610.1 - 4.1e-95 318.3 0.0 4.8e-95 318.1 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 DUF4246 PF14033.1 KUM63611.1 - 4.5e-179 596.2 0.0 5.4e-179 595.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 KUM63611.1 - 0.014 15.6 0.0 0.047 13.9 0.0 1.9 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase MFS_1 PF07690.11 KUM63612.1 - 6.3e-18 64.5 57.4 2.1e-12 46.4 27.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2976 PF11190.3 KUM63612.1 - 0.0023 17.4 0.5 0.027 13.9 0.3 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2976) Condensation PF00668.15 KUM63613.1 - 1e-101 339.7 0.0 1.9e-34 118.9 0.1 4.4 4 0 0 4 4 4 4 Condensation domain AMP-binding PF00501.23 KUM63613.1 - 2.4e-72 243.6 0.0 3.7e-72 243.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 KUM63613.1 - 2.8e-29 101.1 1.0 3.9e-09 36.6 0.0 3.9 3 0 0 3 3 3 3 Phosphopantetheine attachment site WES_acyltransf PF03007.11 KUM63613.1 - 1.6e-05 24.6 0.3 0.0073 15.8 0.0 2.9 3 0 0 3 3 3 2 Wax ester synthase-like Acyl-CoA acyltransferase domain Transferase PF02458.10 KUM63613.1 - 0.091 11.1 0.0 0.2 10.0 0.0 1.5 1 0 0 1 1 1 0 Transferase family ABC_membrane PF00664.18 KUM63615.1 - 8.2e-73 245.1 34.1 1.5e-36 126.2 10.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KUM63615.1 - 8.2e-64 214.0 0.0 1.2e-31 109.7 0.0 3.1 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.14 KUM63615.1 - 1.5e-15 57.0 1.3 3e-05 23.3 0.1 4.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KUM63615.1 - 1.4e-10 41.6 0.5 0.0048 16.9 0.2 4.4 4 0 0 4 4 4 3 AAA domain AAA_29 PF13555.1 KUM63615.1 - 5.2e-09 35.5 0.2 0.0014 18.1 0.0 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KUM63615.1 - 7.4e-08 33.2 0.0 0.023 15.4 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 KUM63615.1 - 1.1e-07 31.9 0.1 0.29 11.2 0.0 4.1 3 1 0 4 4 4 2 AAA domain AAA_16 PF13191.1 KUM63615.1 - 1.2e-07 31.9 1.7 0.0058 16.6 0.6 3.6 3 1 0 3 3 3 2 AAA ATPase domain ABC_ATPase PF09818.4 KUM63615.1 - 5.1e-07 28.6 0.3 0.0014 17.2 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 KUM63615.1 - 5.3e-07 28.9 0.0 0.012 14.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_33 PF13671.1 KUM63615.1 - 2.2e-06 27.5 0.0 0.011 15.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.1 KUM63615.1 - 0.00014 22.2 5.0 0.0016 18.8 0.0 2.9 4 0 0 4 4 2 1 AAA domain AAA_5 PF07728.9 KUM63615.1 - 0.00027 20.6 0.0 1.7 8.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KUM63615.1 - 0.00034 20.0 0.5 1.8 7.9 0.0 3.5 4 0 0 4 4 4 2 AAA domain SbcCD_C PF13558.1 KUM63615.1 - 0.00054 19.8 2.8 0.77 9.7 0.1 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 KUM63615.1 - 0.00092 19.5 0.0 0.98 9.7 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KUM63615.1 - 0.0013 18.2 4.3 1.4 8.3 0.2 3.4 2 1 0 3 3 3 2 AAA-like domain AAA_30 PF13604.1 KUM63615.1 - 0.0028 17.2 0.0 5 6.6 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.1 KUM63615.1 - 0.0034 17.3 0.0 2.3 8.1 0.0 3.1 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KUM63615.1 - 0.011 15.6 0.0 0.45 10.4 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 KUM63615.1 - 0.012 15.8 0.0 7.8 6.7 0.0 2.7 2 0 0 2 2 2 0 RNA helicase DUF3987 PF13148.1 KUM63615.1 - 0.022 13.3 0.0 3.6 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) MobB PF03205.9 KUM63615.1 - 0.028 14.1 0.0 6.9 6.3 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.15 KUM63615.1 - 0.031 12.9 0.0 0.19 10.3 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit AAA_PrkA PF08298.6 KUM63615.1 - 0.052 12.2 0.0 16 4.0 0.0 3.0 3 0 0 3 3 3 0 PrkA AAA domain Zeta_toxin PF06414.7 KUM63615.1 - 0.064 12.3 0.0 0.59 9.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin APS_kinase PF01583.15 KUM63615.1 - 0.091 12.4 0.0 9.3 5.8 0.0 2.9 3 0 0 3 3 3 0 Adenylylsulphate kinase DUF779 PF05610.6 KUM63615.1 - 0.11 12.5 0.1 0.61 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF779) DUF3317 PF11779.3 KUM63616.1 - 7.7e-22 76.4 3.8 7.7e-22 76.4 2.7 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3317) DUF2346 PF09803.4 KUM63617.1 - 0.0018 18.0 2.0 0.0035 17.1 1.4 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) TMEM247 PF15444.1 KUM63617.1 - 0.012 15.4 1.1 0.014 15.2 0.8 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 D123 PF07065.9 KUM63618.1 - 1.7e-88 296.6 0.0 1.4e-85 287.0 0.0 2.1 1 1 1 2 2 2 2 D123 DUF2392 PF10288.4 KUM63618.1 - 0.076 13.3 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) Vps51 PF08700.6 KUM63619.1 - 2.5e-15 56.0 0.0 2.9e-14 52.6 0.0 2.8 2 0 0 2 2 2 1 Vps51/Vps67 YbaB_DNA_bd PF02575.11 KUM63619.1 - 0.02 14.7 0.0 0.078 12.8 0.0 2.0 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family ECH PF00378.15 KUM63620.1 - 3.7e-27 95.0 0.0 4.7e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family UvrD-helicase PF00580.16 KUM63621.1 - 4.2e-13 49.2 0.1 1.3e-08 34.5 0.0 3.4 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 KUM63621.1 - 6e-10 39.1 0.8 3.7e-07 29.9 0.0 3.5 4 0 0 4 4 4 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.1 KUM63621.1 - 2.2e-06 27.7 0.1 4.6e-05 23.4 0.1 2.7 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain SNAP PF14938.1 KUM63621.1 - 1.9e-05 23.9 6.9 2.3e-05 23.6 3.1 2.3 2 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP Clathrin PF00637.15 KUM63621.1 - 0.0031 17.1 0.4 0.61 9.6 0.0 3.7 3 1 1 4 4 4 1 Region in Clathrin and VPS AAA_16 PF13191.1 KUM63621.1 - 0.0059 16.6 0.1 0.38 10.7 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_12 PF13087.1 KUM63621.1 - 0.021 14.2 0.0 0.4 10.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain TPR_7 PF13176.1 KUM63621.1 - 0.037 13.8 3.6 5.6 7.0 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KUM63621.1 - 0.068 12.8 5.8 7.4 6.2 0.1 4.1 3 1 1 4 4 3 0 TPR repeat AAA_22 PF13401.1 KUM63621.1 - 0.093 12.8 0.4 2.8 8.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 KUM63621.1 - 0.11 12.8 1.6 17 5.6 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KUM63621.1 - 0.13 11.7 0.1 9.7 5.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain TPR_1 PF00515.23 KUM63621.1 - 0.27 10.9 8.3 3.1 7.5 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 KUM63621.1 - 3.2 7.9 10.7 5.5 7.1 0.2 5.4 5 2 1 6 6 6 0 Tetratricopeptide repeat DUF1640 PF07798.6 KUM63622.1 - 8.4e-13 48.7 6.4 1.3e-12 48.1 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) ALMT PF11744.3 KUM63622.1 - 0.1 11.1 1.0 0.16 10.6 0.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter RIC3 PF15361.1 KUM63622.1 - 2.2 8.4 0.0 2.2 8.4 0.0 3.8 3 1 0 3 3 3 0 Resistance to inhibitors of cholinesterase homologue 3 Longin PF13774.1 KUM63623.1 - 2.9e-28 97.2 0.9 4.7e-28 96.5 0.6 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KUM63623.1 - 7.4e-15 54.3 0.0 1.4e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Synaptobrevin PilJ PF13675.1 KUM63623.1 - 0.94 9.8 4.2 1.6 9.0 0.4 2.1 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term ASXH PF13919.1 KUM63624.1 - 1.1e-38 132.1 1.1 2.2e-38 131.1 0.8 1.5 1 0 0 1 1 1 1 Asx homology domain AT_hook PF02178.14 KUM63624.1 - 0.92 9.3 11.2 3 7.7 7.8 2.0 1 0 0 1 1 1 0 AT hook motif Transp_cyt_pur PF02133.10 KUM63625.1 - 7.2e-23 80.8 41.3 1.1e-22 80.2 28.6 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin TetR PF13972.1 KUM63625.1 - 0.096 12.1 0.1 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial transcriptional repressor HEAT_2 PF13646.1 KUM63626.1 - 1.6e-12 47.5 3.1 0.0017 18.6 0.0 7.5 6 1 1 7 7 7 4 HEAT repeats HEAT PF02985.17 KUM63626.1 - 7.2e-08 31.8 11.9 0.9 9.7 0.0 9.4 9 0 0 9 9 9 3 HEAT repeat CLASP_N PF12348.3 KUM63626.1 - 0.11 11.8 3.5 5.3 6.3 0.0 4.4 5 1 0 5 5 5 0 CLASP N terminal Cnd1 PF12717.2 KUM63626.1 - 0.13 12.0 3.6 37 4.0 0.1 4.8 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 CENP-I PF07778.6 KUM63628.1 - 5.8e-96 321.7 1.1 7.9e-96 321.2 0.7 1.1 1 0 0 1 1 1 1 Mis6 Transcrip_reg PF01709.15 KUM63629.1 - 1.8e-61 207.2 0.5 2.1e-61 207.0 0.3 1.0 1 0 0 1 1 1 1 Transcriptional regulator Img2 PF05046.9 KUM63630.1 - 0.014 15.5 0.1 5.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) RWD PF05773.17 KUM63631.1 - 2.5e-20 72.4 0.0 3.9e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 KUM63631.1 - 7.1e-16 57.8 45.4 3.5e-13 49.1 3.4 4.3 3 1 1 4 4 4 2 IBR domain zf-RING_5 PF14634.1 KUM63631.1 - 0.00091 18.8 10.7 0.00091 18.8 7.4 4.0 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 KUM63631.1 - 0.0017 18.1 10.1 0.0017 18.1 7.0 3.9 2 1 1 3 3 3 1 Ring finger domain CRT10 PF08728.5 KUM63632.1 - 8.5e-21 73.6 0.0 4.8e-12 44.7 0.0 2.1 2 0 0 2 2 2 2 CRT10 MMtag PF10159.4 KUM63633.1 - 1e-32 112.0 4.7 1e-32 112.0 3.2 2.8 2 1 1 3 3 3 1 Kinase phosphorylation protein Glyco_hydro_63 PF03200.11 KUM63634.1 - 1.7e-249 829.9 0.1 1.2e-248 827.0 0.0 1.8 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 KUM63634.1 - 0.025 13.2 4.7 0.11 11.1 3.3 2.1 1 1 0 1 1 1 0 Trehalase Nif11 PF07862.6 KUM63634.1 - 0.051 13.5 0.3 0.23 11.4 0.1 2.1 2 0 0 2 2 2 0 Nitrogen fixation protein of unknown function UreD PF01774.12 KUM63635.1 - 2.3e-51 174.2 0.0 2.7e-51 174.0 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein Amidohydro_1 PF01979.15 KUM63636.1 - 1.5e-61 208.8 1.5 2.5e-61 208.1 1.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 KUM63636.1 - 6.6e-52 174.7 1.1 1.4e-51 173.7 0.7 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 KUM63636.1 - 3.2e-38 129.5 0.0 6.1e-38 128.6 0.0 1.5 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.13 KUM63636.1 - 5.8e-14 51.9 0.1 1.2e-13 50.8 0.1 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 KUM63636.1 - 9.5e-09 34.9 3.5 3.1e-08 33.2 2.4 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KUM63636.1 - 0.0001 21.7 0.0 0.002 17.4 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 KUM63636.1 - 0.0084 16.1 0.1 2.9 7.8 0.1 2.6 2 0 0 2 2 2 2 Amidohydrolase DUF3402 PF11882.3 KUM63637.1 - 6.6e-164 545.8 0.0 8.8e-164 545.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 KUM63637.1 - 3.7e-92 308.3 0.0 5.6e-92 307.7 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein PAP2 PF01569.16 KUM63638.1 - 6.9e-16 58.0 1.5 6.9e-16 58.0 1.1 2.0 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.9 KUM63638.1 - 0.028 14.1 0.2 0.47 10.1 0.1 2.2 1 1 1 2 2 2 0 Divergent PAP2 family DUF4131 PF13567.1 KUM63638.1 - 1.7 8.0 7.5 0.52 9.6 1.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Arylsulfotrans PF05935.6 KUM63639.1 - 7.6e-13 47.7 0.1 6.9e-08 31.4 0.2 3.1 2 1 1 3 3 3 2 Arylsulfotransferase (ASST) Arylsulfotran_2 PF14269.1 KUM63639.1 - 5.1e-12 45.5 0.0 1.5e-11 43.9 0.0 1.7 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ_2 PF13360.1 KUM63639.1 - 0.00069 19.1 0.1 0.012 15.1 0.1 2.5 2 1 1 3 3 3 2 PQQ-like domain PQQ PF01011.16 KUM63639.1 - 0.061 12.8 0.4 2.4 7.8 0.0 3.5 3 0 0 3 3 3 0 PQQ enzyme repeat adh_short PF00106.20 KUM63640.1 - 1.1e-15 57.9 0.2 1.9e-15 57.1 0.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM63640.1 - 1.6e-08 34.6 0.0 4.2e-08 33.2 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM63640.1 - 1.9e-06 27.6 0.0 2.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 KR domain CLPTM1 PF05602.7 KUM63641.1 - 3.7e-170 566.3 0.0 4.4e-170 566.1 0.0 1.0 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF1240 PF06836.7 KUM63641.1 - 0.15 12.2 3.7 0.41 10.8 2.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) Ferritin_2 PF13668.1 KUM63643.1 - 6.1e-18 65.0 0.2 1.2e-17 64.1 0.1 1.4 1 0 0 1 1 1 1 Ferritin-like domain SGL PF08450.7 KUM63644.1 - 3.6e-05 23.2 0.1 6.5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region EthD PF07110.6 KUM63645.1 - 0.0046 17.8 0.0 0.0078 17.1 0.0 1.4 1 1 0 1 1 1 1 EthD domain ABM PF03992.11 KUM63645.1 - 0.085 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase DUF4112 PF13430.1 KUM63646.1 - 1.9e-33 114.5 0.4 2.5e-33 114.1 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DCP2 PF05026.8 KUM63647.1 - 3.3e-36 123.0 1.7 5.8e-36 122.2 1.2 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 KUM63647.1 - 1.5e-16 60.2 0.0 3.1e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Lung_7-TM_R PF06814.8 KUM63648.1 - 6.8e-70 235.3 17.8 8.2e-70 235.0 12.4 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor PrgI PF12666.2 KUM63648.1 - 0.029 14.4 16.2 0.55 10.4 0.8 3.6 2 1 1 3 3 3 0 PrgI family protein DUF2392 PF10288.4 KUM63649.1 - 9.1e-25 87.0 0.0 2.1e-24 85.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) DUF1308 PF07000.6 KUM63650.1 - 5.2e-98 328.0 0.0 7e-98 327.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) UPF0561 PF10573.4 KUM63650.1 - 0.63 9.9 3.1 2.8 7.7 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein family UPF0561 APH PF01636.18 KUM63651.1 - 0.0043 16.8 0.1 0.0077 15.9 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF4199 PF13858.1 KUM63651.1 - 0.063 13.1 0.0 0.095 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Mei4 PF13971.1 KUM63652.1 - 0.026 13.4 0.0 0.026 13.4 0.0 3.0 3 1 0 3 3 3 0 Meiosis-specific protein Mei4 Mnd1 PF03962.10 KUM63652.1 - 3.8 7.1 9.8 0.32 10.6 3.1 2.0 2 1 0 2 2 2 0 Mnd1 family Amidohydro_2 PF04909.9 KUM63653.1 - 1.5e-32 113.2 0.6 6.2e-32 111.2 0.4 1.8 1 1 0 1 1 1 1 Amidohydrolase DIOX_N PF14226.1 KUM63654.1 - 1.5e-22 80.2 0.0 3e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KUM63654.1 - 5.1e-17 61.9 0.0 1.2e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HSBP1 PF06825.7 KUM63655.1 - 2.8e-18 65.2 0.1 4.3e-18 64.6 0.1 1.3 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.4 KUM63655.1 - 0.00061 19.1 0.9 0.15 11.4 0.1 2.4 1 1 1 2 2 2 2 Trimeric coiled-coil oligomerisation domain of matrilin NPV_P10 PF05531.7 KUM63655.1 - 0.02 15.0 0.2 0.038 14.2 0.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 KUM63655.1 - 0.029 14.1 0.2 0.041 13.7 0.2 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4164 PF13747.1 KUM63655.1 - 0.037 14.1 0.2 0.065 13.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Vinculin PF01044.14 KUM63655.1 - 0.041 11.8 0.1 0.048 11.6 0.1 1.0 1 0 0 1 1 1 0 Vinculin family Prp19 PF08606.6 KUM63655.1 - 0.11 12.2 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Prp19/Pso4-like Ebp2 PF05890.7 KUM63656.1 - 7.5e-90 300.9 15.8 7.5e-90 300.9 11.0 2.1 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 TRAP_alpha PF03896.11 KUM63656.1 - 0.96 8.3 13.1 2.4 7.0 9.1 1.7 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CPSF100_C PF13299.1 KUM63656.1 - 1.6 8.9 13.9 3.1 7.9 4.5 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Prothymosin PF03247.9 KUM63656.1 - 8.1 6.6 51.0 1.2 9.2 25.9 2.9 2 1 1 3 3 3 0 Prothymosin/parathymosin family zf-MYND PF01753.13 KUM63657.1 - 2.2e-07 30.6 20.6 4.3e-07 29.6 14.3 1.5 1 0 0 1 1 1 1 MYND finger DIOX_N PF14226.1 KUM63658.1 - 4.6e-19 69.0 0.0 6.8e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KUM63658.1 - 1.4e-10 41.3 0.0 5.5e-10 39.4 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Thioredoxin PF00085.15 KUM63659.1 - 4.2e-60 199.8 0.4 2.5e-30 104.2 0.0 2.6 3 0 0 3 3 3 2 Thioredoxin ERp29 PF07749.7 KUM63659.1 - 2.6e-22 79.2 0.5 8.6e-22 77.5 0.4 1.9 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 KUM63659.1 - 1.9e-20 73.0 0.2 5.3e-09 36.2 0.0 3.2 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KUM63659.1 - 2.3e-16 59.5 0.0 1.5e-08 34.4 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 KUM63659.1 - 1.4e-12 47.5 0.0 2.2e-05 24.4 0.0 3.4 2 2 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 KUM63659.1 - 2.1e-08 33.9 0.2 0.0074 15.9 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_6 PF13848.1 KUM63659.1 - 2.6e-07 30.6 0.5 0.068 12.9 0.0 3.5 3 1 0 3 3 3 2 Thioredoxin-like domain Redoxin PF08534.5 KUM63659.1 - 2.8e-07 30.2 0.6 0.0055 16.2 0.1 2.5 2 1 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 KUM63659.1 - 0.00039 19.9 0.0 0.23 11.0 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_3 PF13192.1 KUM63659.1 - 0.00061 19.5 0.0 0.44 10.3 0.0 2.9 3 0 0 3 3 3 1 Thioredoxin domain Thioredoxin_4 PF13462.1 KUM63659.1 - 0.0016 18.4 1.4 4.2 7.3 0.1 4.0 2 2 1 3 3 3 1 Thioredoxin TraF PF13728.1 KUM63659.1 - 0.0051 16.3 0.0 0.34 10.3 0.0 2.2 2 0 0 2 2 2 1 F plasmid transfer operon protein DSBA PF01323.15 KUM63659.1 - 0.015 14.9 1.6 9.8 5.6 0.0 3.7 3 2 1 4 4 4 0 DSBA-like thioredoxin domain Glutaredoxin PF00462.19 KUM63659.1 - 0.034 14.1 0.6 8.2 6.5 0.0 3.2 2 2 0 2 2 2 0 Glutaredoxin HyaE PF07449.6 KUM63659.1 - 0.035 14.0 0.0 1.9 8.4 0.0 2.6 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE DDE_Tnp_1_2 PF13586.1 KUM63659.1 - 0.049 13.8 0.0 0.19 11.9 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain Phosducin PF02114.11 KUM63660.1 - 3.8e-16 58.6 0.0 1e-14 53.9 0.0 2.2 1 1 0 1 1 1 1 Phosducin CoA_transf_3 PF02515.12 KUM63661.1 - 1.4e-31 109.2 0.0 4.3e-31 107.6 0.0 1.7 2 0 0 2 2 2 1 CoA-transferase family III ABC_tran PF00005.22 KUM63662.1 - 1.6e-24 86.7 0.0 2.1e-13 50.7 0.0 3.0 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KUM63662.1 - 2.9e-16 60.3 1.1 1.5e-07 31.6 0.0 3.2 2 1 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KUM63662.1 - 3e-07 30.2 0.0 0.0077 16.1 0.0 2.4 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KUM63662.1 - 0.0017 17.8 0.0 0.0035 16.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 KUM63662.1 - 0.0027 16.8 0.0 0.92 8.4 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 KUM63662.1 - 0.0049 17.2 0.2 0.0086 16.4 0.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KUM63662.1 - 0.0052 16.9 0.2 0.24 11.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.14 KUM63662.1 - 0.0063 15.7 0.0 0.54 9.4 0.0 2.5 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.7 KUM63662.1 - 0.023 14.3 0.0 0.06 12.9 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_10 PF12846.2 KUM63662.1 - 0.062 12.7 0.0 0.21 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain AAA_16 PF13191.1 KUM63662.1 - 0.099 12.6 0.6 0.22 11.4 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain cobW PF02492.14 KUM63662.1 - 0.17 11.3 0.0 0.39 10.1 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 KUM63662.1 - 0.18 10.9 0.0 0.35 10.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 EthD PF07110.6 KUM63663.1 - 1.1e-11 45.5 0.2 1.4e-11 45.1 0.1 1.1 1 0 0 1 1 1 1 EthD domain WD40 PF00400.27 KUM63664.1 - 6.7e-33 111.3 11.0 1.2e-10 40.7 0.0 7.2 8 0 0 8 8 8 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KUM63664.1 - 0.0013 17.0 0.0 0.54 8.5 0.0 3.5 3 1 1 4 4 4 2 Cytochrome D1 heme domain eIF2A PF08662.6 KUM63664.1 - 0.015 14.9 0.0 0.074 12.7 0.0 2.2 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.1 KUM63664.1 - 0.087 12.6 0.0 17 5.2 0.0 3.8 3 2 2 5 5 5 0 Ciliary BBSome complex subunit 2, middle region Ribonuc_red_sm PF00268.16 KUM63665.1 - 3e-120 400.4 0.6 3.5e-120 400.2 0.4 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain RE_XcyI PF09571.5 KUM63665.1 - 0.13 11.1 0.2 6.6 5.5 0.0 2.1 2 0 0 2 2 2 0 XcyI restriction endonuclease TruB_N PF01509.13 KUM63666.1 - 6.1e-46 156.2 0.1 3.5e-45 153.8 0.0 2.2 2 1 1 3 3 3 1 TruB family pseudouridylate synthase (N terminal domain) Baculo_PP31 PF05311.6 KUM63666.1 - 0.055 12.7 0.0 0.12 11.5 0.0 1.5 1 1 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) SRP9-21 PF05486.7 KUM63668.1 - 1.9e-30 104.3 0.3 2.4e-30 104.0 0.2 1.1 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) DNMT1-RFD PF12047.3 KUM63669.1 - 7e-06 25.7 0.0 1.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain OHCU_decarbox PF09349.5 KUM63670.1 - 4.5e-31 108.2 0.0 5.1e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase Tymo_45kd_70kd PF03251.8 KUM63670.1 - 0.0081 14.9 0.3 0.0096 14.6 0.2 1.0 1 0 0 1 1 1 1 Tymovirus 45/70Kd protein GCV_T PF01571.16 KUM63671.1 - 4.1e-13 49.1 0.0 9.3e-13 48.0 0.0 1.7 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KUM63671.1 - 0.00013 21.9 0.0 0.00034 20.5 0.0 1.7 1 1 1 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain VIT_2 PF13757.1 KUM63671.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain WD40 PF00400.27 KUM63672.1 - 1.2e-11 43.9 4.6 8.4e-06 25.4 0.0 5.4 7 0 0 7 7 7 2 WD domain, G-beta repeat DUF3312 PF11768.3 KUM63672.1 - 0.081 11.1 0.0 0.12 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Kelch_4 PF13418.1 KUM63672.1 - 0.11 12.2 0.3 29 4.5 0.0 3.0 2 0 0 2 2 2 0 Galactose oxidase, central domain Mito_carr PF00153.22 KUM63673.1 - 8.2e-57 188.9 4.6 1.5e-19 69.4 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MscL PF01741.13 KUM63674.1 - 6.4e-15 55.4 1.0 1.6e-14 54.1 0.7 1.6 1 1 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL zf-ribbon_3 PF13248.1 KUM63674.1 - 0.029 13.5 1.1 0.049 12.8 0.7 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zf-C3HC4_3 PF13920.1 KUM63674.1 - 0.066 12.8 0.5 0.066 12.8 0.3 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.7 KUM63674.1 - 0.091 12.8 0.6 0.18 11.9 0.4 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.2 KUM63674.1 - 0.1 12.4 0.6 0.16 11.7 0.4 1.3 1 0 0 1 1 1 0 Double zinc ribbon UPF0547 PF10571.4 KUM63674.1 - 0.13 11.9 1.4 0.23 11.1 1.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-FCS PF06467.9 KUM63674.1 - 1.1 8.9 4.5 0.54 9.9 0.1 2.2 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-LSD1 PF06943.7 KUM63674.1 - 1.4 8.5 4.6 10 5.8 0.5 2.3 2 0 0 2 2 2 0 LSD1 zinc finger AMP-binding PF00501.23 KUM63675.1 - 2.9e-70 236.7 0.0 4e-70 236.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KUM63675.1 - 6.9e-16 58.9 0.0 1.9e-15 57.5 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short PF00106.20 KUM63677.1 - 1.8e-18 67.0 0.4 8.1e-13 48.6 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KUM63677.1 - 3.2e-13 50.0 0.2 1.1e-11 45.0 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM63677.1 - 8.4e-08 32.0 0.9 1.9e-07 30.8 0.1 1.9 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 KUM63677.1 - 0.00051 19.0 0.1 0.00084 18.3 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KUM63677.1 - 0.001 19.1 0.1 0.0019 18.3 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.14 KUM63677.1 - 0.0015 17.3 0.1 0.0034 16.1 0.0 1.6 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 KUM63677.1 - 0.0037 16.2 0.2 0.0055 15.7 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 KUM63677.1 - 0.0073 15.7 0.1 0.026 13.9 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 KUM63677.1 - 0.033 13.3 0.0 0.05 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Response_reg PF00072.19 KUM63678.1 - 3.4e-23 81.7 0.2 6.8e-23 80.8 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 KUM63678.1 - 6.2e-18 64.5 0.1 1.3e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KUM63678.1 - 2.9e-11 43.1 0.1 1e-10 41.4 0.1 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 KUM63678.1 - 0.0011 19.0 0.0 0.19 11.8 0.0 2.9 3 0 0 3 3 3 1 GAF domain KR PF08659.5 KUM63678.1 - 0.045 13.4 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 KR domain GpcrRhopsn4 PF10192.4 KUM63679.1 - 0.76 8.9 9.1 0.043 13.0 2.4 1.6 2 0 0 2 2 2 0 Rhodopsin-like GPCR transmembrane domain SdpI PF13630.1 KUM63679.1 - 7.2 6.3 8.8 1.6e+02 2.0 6.1 2.7 1 1 0 1 1 1 0 SdpI/YhfL protein family DnaJ PF00226.26 KUM63680.1 - 9.4e-20 70.1 1.0 2.9e-19 68.5 0.7 1.9 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.17 KUM63680.1 - 0.035 13.7 0.1 0.14 11.7 0.1 2.1 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MKT1_C PF12246.3 KUM63681.1 - 2.1e-75 252.8 0.0 2.8e-75 252.4 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 KUM63681.1 - 1.7e-30 105.2 0.0 3.9e-30 103.9 0.0 1.7 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 KUM63681.1 - 5.9e-13 48.6 0.0 1.1e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KUM63681.1 - 2e-05 24.7 0.0 4.4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain WD40 PF00400.27 KUM63683.1 - 3.3e-49 163.0 21.8 1.3e-08 34.4 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KUM63683.1 - 0.00011 21.9 0.0 0.099 12.3 0.0 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A SRP-alpha_N PF04086.8 KUM63684.1 - 0.38 10.0 4.5 0.62 9.3 3.1 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal C2 PF00168.25 KUM63685.1 - 2.2e-20 72.2 0.0 2e-14 53.1 0.0 2.5 2 0 0 2 2 2 2 C2 domain Fungal_trans PF04082.13 KUM63686.1 - 1e-22 80.3 0.7 2.3e-22 79.1 0.5 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Prenyltrans_1 PF13243.1 KUM63686.1 - 0.12 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Prenyltransferase-like Fungal_trans PF04082.13 KUM63687.1 - 3.6e-05 22.7 0.2 5.6e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM63688.1 - 0.91 9.4 7.9 1.6 8.6 5.5 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain EF-hand_1 PF00036.27 KUM63689.1 - 1.1e-13 49.3 2.1 5.3e-05 22.2 0.0 3.6 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 KUM63689.1 - 2.1e-12 45.7 6.9 1.7e-05 24.2 0.2 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 KUM63689.1 - 4.3e-12 45.9 4.1 6.8e-07 29.3 0.1 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KUM63689.1 - 6.6e-11 41.6 0.8 3.4e-08 32.9 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.2 KUM63689.1 - 0.075 12.7 0.0 0.19 11.5 0.0 1.6 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.1 KUM63689.1 - 0.62 9.5 8.3 4.5 6.8 0.3 3.3 3 0 0 3 3 3 0 EF hand Reprolysin_5 PF13688.1 KUM63690.1 - 8e-59 198.8 9.2 8e-59 198.8 6.4 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KUM63690.1 - 5.1e-43 146.9 4.4 1.1e-42 145.9 3.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KUM63690.1 - 1.2e-42 145.9 5.7 2.2e-42 145.0 3.9 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 KUM63690.1 - 4e-19 68.6 34.6 4e-19 68.6 24.0 4.5 3 1 1 4 4 4 1 Disintegrin Reprolysin_3 PF13582.1 KUM63690.1 - 6.9e-17 62.1 4.0 7.2e-17 62.0 0.3 2.5 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.14 KUM63690.1 - 2.9e-05 23.8 0.0 6e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Reprolysin family propeptide Mid2 PF04478.7 KUM63690.1 - 0.00099 18.5 1.3 0.0056 16.1 0.1 2.3 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor Peptidase_M10 PF00413.19 KUM63690.1 - 0.012 15.3 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 Matrixin IMS PF00817.15 KUM63691.1 - 1.3e-35 122.4 0.0 2.2e-35 121.6 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KUM63691.1 - 1.5e-10 41.0 0.1 3.6e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KUM63691.1 - 1.2e-05 25.0 0.0 3.8e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif HHH_5 PF14520.1 KUM63691.1 - 0.1 12.8 0.0 0.36 11.0 0.0 2.0 1 1 0 1 1 1 0 Helix-hairpin-helix domain HHH_8 PF14716.1 KUM63691.1 - 0.11 12.7 0.0 0.83 9.8 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain DUF2424 PF10340.4 KUM63692.1 - 0.068 11.8 0.0 0.068 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Alk_phosphatase PF00245.15 KUM63693.1 - 1.8e-66 224.6 1.0 3e-66 223.8 0.7 1.3 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.18 KUM63693.1 - 3.6e-08 32.9 6.6 1.3e-06 27.8 4.6 2.5 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KUM63693.1 - 3.3e-06 26.6 2.7 5.6e-06 25.9 1.7 1.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KUM63693.1 - 0.00072 18.0 0.3 0.0012 17.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) FTA4 PF13093.1 KUM63693.1 - 0.0063 15.9 0.1 0.0092 15.4 0.1 1.2 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF1501 PF07394.7 KUM63693.1 - 0.027 13.3 0.2 0.045 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Metalloenzyme PF01676.13 KUM63693.1 - 0.063 12.6 0.7 0.14 11.4 0.5 1.5 1 0 0 1 1 1 0 Metalloenzyme superfamily zf-MYND PF01753.13 KUM63694.1 - 0.69 9.8 6.3 2 8.3 4.3 1.9 1 0 0 1 1 1 0 MYND finger Podoplanin PF05808.6 KUM63694.1 - 9.7 5.7 7.6 21 4.6 5.2 1.5 1 0 0 1 1 1 0 Podoplanin MgsA_C PF12002.3 KUM63695.1 - 4.5e-57 192.4 0.0 7.9e-57 191.6 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 KUM63695.1 - 1.1e-12 48.2 0.0 2.8e-12 46.9 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KUM63695.1 - 3.3e-10 39.4 0.0 2.4e-09 36.6 0.0 1.9 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 KUM63695.1 - 1.7e-05 24.0 0.0 0.12 11.4 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KUM63695.1 - 4.4e-05 23.2 0.0 0.00094 18.9 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KUM63695.1 - 4.7e-05 22.9 0.0 0.002 17.6 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_19 PF13245.1 KUM63695.1 - 0.00038 20.1 0.0 0.00081 19.0 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_3 PF07726.6 KUM63695.1 - 0.0012 18.4 0.0 0.0047 16.5 0.0 2.0 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KUM63695.1 - 0.0021 18.1 0.2 0.0096 16.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 KUM63695.1 - 0.0037 16.2 0.0 0.0059 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.1 KUM63695.1 - 0.0045 17.0 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.1 KUM63695.1 - 0.0048 16.7 0.0 0.0088 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 KUM63695.1 - 0.0066 16.2 0.1 3.3 7.4 0.0 2.4 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_16 PF13191.1 KUM63695.1 - 0.0071 16.3 0.1 0.14 12.0 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 KUM63695.1 - 0.017 13.8 0.1 0.094 11.4 0.0 1.9 1 1 0 2 2 2 0 TIP49 C-terminus PIF1 PF05970.9 KUM63695.1 - 0.033 13.1 0.1 0.051 12.5 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_30 PF13604.1 KUM63695.1 - 0.036 13.6 0.1 0.12 11.9 0.1 1.7 1 1 1 2 2 2 0 AAA domain DUF927 PF06048.6 KUM63695.1 - 0.094 11.9 0.1 0.17 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF927) AAA_29 PF13555.1 KUM63695.1 - 0.11 12.0 0.1 6.1 6.4 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_17 PF13207.1 KUM63695.1 - 0.12 13.2 0.0 0.36 11.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KUM63695.1 - 0.18 10.6 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF605 PF04652.11 KUM63695.1 - 0.18 11.1 9.7 0.27 10.5 6.7 1.1 1 0 0 1 1 1 0 Vta1 like Aminotran_1_2 PF00155.16 KUM63696.1 - 1.2e-67 228.4 0.0 1.3e-67 228.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KUM63696.1 - 0.0045 16.1 0.0 0.0066 15.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 KUM63696.1 - 0.015 13.5 0.0 0.024 12.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Ald_Xan_dh_C2 PF02738.13 KUM63697.1 - 1.6e-199 663.8 0.7 2.2e-199 663.3 0.5 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 KUM63697.1 - 1.5e-49 167.7 0.0 2.6e-49 166.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 KUM63697.1 - 6.2e-32 109.9 0.0 1.5e-31 108.7 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.12 KUM63697.1 - 1.5e-31 108.3 0.5 4.3e-31 106.8 0.0 2.1 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 KUM63697.1 - 6.4e-11 41.9 0.0 1.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 [2Fe-2S] binding domain Tetraspannin PF00335.15 KUM63697.1 - 0.21 10.8 4.9 0.36 10.0 3.4 1.2 1 0 0 1 1 1 0 Tetraspanin family Baculo_PEP_C PF04513.7 KUM63698.1 - 0.0053 16.5 4.3 0.065 13.0 0.2 2.8 3 0 0 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus Rifin_STEVOR PF02009.11 KUM63698.1 - 0.088 12.4 3.9 2.9 7.4 0.1 2.6 3 0 0 3 3 3 0 Rifin/stevor family YbaJ PF10757.4 KUM63698.1 - 0.16 12.1 1.3 1.2 9.2 0.2 2.7 2 1 1 3 3 3 0 Biofilm formation regulator YbaJ PgaD PF13994.1 KUM63698.1 - 0.52 9.7 6.6 0.31 10.5 0.0 3.0 3 0 0 3 3 3 0 PgaD-like protein Homeobox_KN PF05920.6 KUM63699.1 - 6.5e-16 57.7 1.2 2.2e-15 56.0 0.8 2.0 1 0 0 1 1 1 1 Homeobox KN domain zf-C2H2_4 PF13894.1 KUM63699.1 - 4.6e-08 32.8 22.1 0.041 14.2 3.7 4.8 3 1 0 3 3 3 3 C2H2-type zinc finger Homeobox PF00046.24 KUM63699.1 - 2.1e-07 30.4 4.2 4.3e-07 29.4 2.9 1.6 1 0 0 1 1 1 1 Homeobox domain zf-C2H2 PF00096.21 KUM63699.1 - 1.6e-06 28.0 20.7 0.15 12.4 3.8 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type HA PF03457.9 KUM63699.1 - 0.019 15.0 1.8 0.34 11.0 0.2 2.7 2 0 0 2 2 2 0 Helicase associated domain Fer2_2 PF01799.15 KUM63699.1 - 0.18 11.6 0.9 26 4.7 0.0 3.2 3 0 0 3 3 3 0 [2Fe-2S] binding domain FANCL_C PF11793.3 KUM63699.1 - 0.53 10.2 4.7 1.1 9.2 2.1 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain zf-met PF12874.2 KUM63699.1 - 1.8 8.8 0.0 1.8 8.8 0.0 4.2 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Aa_trans PF01490.13 KUM63700.1 - 3.6e-40 137.7 29.7 4.5e-40 137.3 20.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2985 PF11204.3 KUM63700.1 - 0.13 12.0 0.0 0.13 12.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2985) CAAD PF14159.1 KUM63700.1 - 3 7.5 8.4 9.8 5.8 0.1 3.6 3 1 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase NAD_binding_10 PF13460.1 KUM63701.1 - 1.3e-15 57.8 0.0 1.7e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KUM63701.1 - 0.1 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Fungal_trans PF04082.13 KUM63702.1 - 7.2e-20 70.9 0.0 1.3e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM63702.1 - 1.7e-08 34.2 13.9 2.8e-08 33.5 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain T4SS PF07996.6 KUM63702.1 - 0.033 14.0 0.0 0.078 12.8 0.0 1.6 1 0 0 1 1 1 0 Type IV secretion system proteins Tsp45I PF06300.7 KUM63702.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Tsp45I type II restriction enzyme Cys_Met_Meta_PP PF01053.15 KUM63703.1 - 3.4e-115 384.4 0.0 3.8e-115 384.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KUM63703.1 - 3.4e-07 29.5 0.1 5e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KUM63703.1 - 0.00042 19.4 0.2 0.00055 19.0 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 KUM63703.1 - 0.004 15.9 0.1 0.0054 15.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KUM63703.1 - 0.014 14.5 0.3 0.043 12.9 0.2 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase Peptidase_M20 PF01546.23 KUM63704.1 - 1.1e-27 96.8 0.0 1.4e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 KUM63704.1 - 5.2e-06 26.3 0.0 1.5e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 M20_dimer PF07687.9 KUM63704.1 - 0.00019 21.1 0.0 0.00039 20.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain AMP-binding PF00501.23 KUM63705.1 - 1.6e-90 303.4 0.1 2e-90 303.1 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KUM63705.1 - 4.7e-22 78.7 0.4 1.4e-20 73.9 0.2 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Octopine_DH PF02317.12 KUM63706.1 - 1.4e-42 144.9 0.0 2.1e-42 144.3 0.0 1.2 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain NAD_Gly3P_dh_N PF01210.18 KUM63706.1 - 6.1e-12 45.5 0.0 1.2e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_8 PF13450.1 KUM63706.1 - 0.00051 19.9 0.1 0.0011 18.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KUM63706.1 - 0.0012 18.7 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 KUM63706.1 - 0.0024 18.2 0.0 0.0056 17.0 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GIDA PF01134.17 KUM63706.1 - 0.0039 16.0 0.8 0.0055 15.6 0.1 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A ApbA PF02558.11 KUM63706.1 - 0.0048 16.3 0.0 0.0082 15.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 KUM63706.1 - 0.0061 15.4 0.0 0.0086 14.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KUM63706.1 - 0.01 14.7 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 KUM63706.1 - 0.02 15.2 0.0 0.039 14.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KUM63706.1 - 0.022 13.2 0.0 0.033 12.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 KUM63706.1 - 0.03 13.3 0.0 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 KUM63706.1 - 0.058 13.4 0.1 0.17 11.9 0.1 1.8 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KUM63706.1 - 0.07 12.1 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KUM63706.1 - 0.092 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.11 KUM63707.1 - 1e-54 185.6 9.7 1e-54 185.6 6.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM63707.1 - 1.5e-13 50.1 10.0 1.5e-13 50.1 7.0 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.2 KUM63707.1 - 4.5e-06 26.3 2.8 0.017 14.9 0.0 3.4 3 0 0 3 3 3 2 MFS_1 like family TRI12 PF06609.8 KUM63707.1 - 0.00013 20.2 2.5 0.00024 19.4 1.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 KUM63707.1 - 0.00014 20.6 5.3 0.0022 16.7 1.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF791) MFS_3 PF05977.8 KUM63707.1 - 4.5 5.2 18.2 0.041 11.9 3.9 2.8 2 1 1 3 3 3 0 Transmembrane secretion effector MFS_1 PF07690.11 KUM63709.1 - 1.2e-06 27.4 8.9 1.4e-06 27.2 6.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM63709.1 - 3.2e-05 22.7 5.9 3.7e-05 22.4 4.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF2678 PF10856.3 KUM63709.1 - 0.04 13.6 0.1 0.073 12.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2678) MFS_1 PF07690.11 KUM63710.1 - 7.2e-06 24.9 24.2 1.5e-05 23.8 16.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Pox_A14 PF05767.7 KUM63710.1 - 0.12 12.3 2.2 37 4.3 0.2 3.4 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 PALP PF00291.20 KUM63711.1 - 4.5e-55 187.0 0.3 4.5e-55 187.0 0.2 1.8 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.23 KUM63711.1 - 7.4e-30 103.8 0.0 1.4e-29 102.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KUM63711.1 - 2.7e-18 65.7 0.0 8.7e-18 64.1 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KUM63711.1 - 0.017 14.8 0.1 0.038 13.7 0.1 1.6 1 0 0 1 1 1 0 Peptidase family M28 GET2 PF08690.5 KUM63712.1 - 1.1e-06 28.1 0.4 2.8e-06 26.7 0.2 1.6 2 0 0 2 2 2 1 GET complex subunit GET2 Neisseria_TspB PF05616.8 KUM63712.1 - 9.8 4.4 6.2 15 3.8 4.3 1.4 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein adh_short_C2 PF13561.1 KUM63713.1 - 6.1e-34 117.8 0.0 7e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KUM63713.1 - 6.8e-28 97.6 0.1 8.5e-28 97.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM63713.1 - 5.1e-10 39.3 0.1 6.8e-10 38.8 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF1719 PF08224.6 KUM63713.1 - 0.021 13.9 0.1 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) ApoA-II PF04711.8 KUM63713.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Apolipoprotein A-II (ApoA-II) DUF678 PF05077.7 KUM63714.1 - 1.8 8.6 5.1 2 8.4 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF678) NST1 PF13945.1 KUM63714.1 - 4.2 7.3 11.4 4 7.4 7.9 1.0 1 0 0 1 1 1 0 Salt tolerance down-regulator Aa_trans PF01490.13 KUM63717.1 - 8.5e-39 133.1 35.9 1e-38 132.9 24.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2897 PF11446.3 KUM63717.1 - 0.19 11.5 1.2 0.58 10.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) Sugar_tr PF00083.19 KUM63718.1 - 3.9e-115 385.0 24.5 5.3e-115 384.5 17.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM63718.1 - 2.2e-29 102.3 50.5 8.8e-28 97.0 18.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KUM63718.1 - 2.9e-05 22.5 3.0 2.9e-05 22.5 2.1 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 KUM63719.1 - 2.3e-59 201.1 0.0 3e-59 200.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sec34 PF04136.10 KUM63719.1 - 0.075 12.7 0.1 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Sec34-like family AA_permease_2 PF13520.1 KUM63720.1 - 1.6e-47 162.0 44.7 2e-47 161.7 31.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM63720.1 - 1.8e-24 85.9 37.5 2.6e-24 85.3 26.0 1.2 1 0 0 1 1 1 1 Amino acid permease YlaH PF14036.1 KUM63720.1 - 2.8 8.0 12.3 0.049 13.7 2.3 2.8 3 0 0 3 3 3 0 YlaH-like protein NmrA PF05368.8 KUM63721.1 - 1.1e-19 70.6 0.0 1.4e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KUM63721.1 - 0.0041 17.1 0.0 0.03 14.3 0.0 2.5 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KUM63721.1 - 0.018 14.0 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase ThiF PF00899.16 KUM63721.1 - 0.048 13.4 0.2 1.9 8.3 0.2 2.3 1 1 1 2 2 2 0 ThiF family Shikimate_DH PF01488.15 KUM63721.1 - 0.11 12.5 0.0 0.95 9.5 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Peptidase_M20 PF01546.23 KUM63722.1 - 6.1e-23 81.3 0.1 1.5e-22 80.0 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KUM63722.1 - 4.6e-16 58.5 0.0 7.6e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KUM63722.1 - 0.017 14.8 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 Aminotran_1_2 PF00155.16 KUM63723.1 - 6.6e-72 242.4 0.0 7.5e-72 242.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KUM63723.1 - 0.0099 15.0 0.0 0.018 14.1 0.0 1.4 2 0 0 2 2 2 1 Beta-eliminating lyase APH PF01636.18 KUM63724.1 - 0.026 14.2 0.2 0.22 11.2 0.2 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family Lir1 PF07207.6 KUM63724.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Light regulated protein Lir1 WD40 PF00400.27 KUM63725.1 - 4.4e-137 441.6 33.6 6.6e-13 47.9 0.1 11.8 11 0 0 11 11 11 11 WD domain, G-beta repeat PD40 PF07676.7 KUM63725.1 - 5.2e-17 61.1 11.2 0.38 10.4 0.0 10.2 10 0 0 10 10 10 5 WD40-like Beta Propeller Repeat Nup160 PF11715.3 KUM63725.1 - 1.2e-15 56.6 18.4 0.011 13.8 0.1 9.0 2 2 4 6 6 6 5 Nucleoporin Nup120/160 PNP_UDP_1 PF01048.15 KUM63725.1 - 1.7e-12 46.8 0.0 3.1e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 KUM63725.1 - 1.1e-10 41.4 0.1 2.3e-10 40.3 0.1 1.5 1 0 0 1 1 1 1 NACHT domain Gmad1 PF10647.4 KUM63725.1 - 3.7e-07 29.8 7.9 0.16 11.3 0.4 5.8 2 2 2 5 5 5 2 Lipoprotein LpqB beta-propeller domain Proteasome_A_N PF10584.4 KUM63725.1 - 1e-05 24.7 2.3 56 3.1 0.0 7.4 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature Nucleoporin_N PF08801.6 KUM63725.1 - 0.00022 20.1 15.7 1.7 7.3 0.3 6.1 1 1 2 4 4 4 3 Nup133 N terminal like DUF1258 PF06869.7 KUM63725.1 - 0.00052 19.1 2.2 17 4.3 0.0 6.0 2 2 3 6 6 6 0 Protein of unknown function (DUF1258) AAA_16 PF13191.1 KUM63725.1 - 0.004 17.1 0.0 0.014 15.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Peptidase_M3 PF01432.15 KUM63725.1 - 0.016 14.2 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M3 DPPIV_N PF00930.16 KUM63725.1 - 0.056 12.0 1.8 90 1.4 0.0 5.7 7 1 1 8 8 8 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region KAP_NTPase PF07693.9 KUM63725.1 - 0.14 11.1 0.1 0.88 8.4 0.0 1.9 1 1 0 2 2 2 0 KAP family P-loop domain Cytochrom_D1 PF02239.11 KUM63725.1 - 0.16 10.2 1.8 7.7 4.6 0.0 3.3 2 2 0 2 2 2 0 Cytochrome D1 heme domain SIR2 PF02146.12 KUM63727.1 - 1.2e-30 106.5 0.0 2.4e-30 105.6 0.0 1.5 1 1 0 1 1 1 1 Sir2 family adh_short PF00106.20 KUM63728.1 - 1.2e-16 61.1 0.6 2.9e-16 59.8 0.2 1.8 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 KUM63728.1 - 5.1e-06 26.2 0.1 8.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 KR domain CRCB PF02537.10 KUM63728.1 - 0.039 13.8 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 CrcB-like protein ABC_tran PF00005.22 KUM63729.1 - 3e-44 150.6 0.0 3.5e-27 95.3 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 KUM63729.1 - 3.1e-16 59.5 21.5 6.3e-13 48.7 4.7 3.2 2 1 1 3 3 3 2 ABC transporter transmembrane region AAA_23 PF13476.1 KUM63729.1 - 1.8e-09 38.2 0.0 0.00034 21.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 KUM63729.1 - 6.3e-09 36.2 0.2 0.018 15.0 0.0 4.2 3 1 1 4 4 4 1 AAA domain SMC_N PF02463.14 KUM63729.1 - 9e-09 34.8 0.2 0.01 15.0 0.0 3.5 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KUM63729.1 - 9.2e-09 35.5 0.0 0.0077 16.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 KUM63729.1 - 2.3e-08 33.4 0.1 0.0021 17.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KUM63729.1 - 1.1e-07 31.2 0.6 0.013 14.9 0.0 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KUM63729.1 - 2.3e-07 30.9 0.0 0.025 14.5 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain MobB PF03205.9 KUM63729.1 - 3.5e-07 30.0 0.7 0.032 13.9 0.0 2.9 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KUM63729.1 - 4.7e-06 26.5 0.0 0.11 12.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KUM63729.1 - 9.2e-06 25.5 0.0 0.066 13.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 KUM63729.1 - 1e-05 25.1 0.1 0.11 11.9 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain Miro PF08477.8 KUM63729.1 - 1.1e-05 25.8 0.0 0.061 13.8 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein cobW PF02492.14 KUM63729.1 - 2.5e-05 23.8 0.7 0.08 12.3 0.1 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 KUM63729.1 - 3.5e-05 22.8 0.0 0.008 15.1 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.24 KUM63729.1 - 3.9e-05 23.8 0.0 0.081 13.1 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KUM63729.1 - 4e-05 23.4 0.0 0.28 10.8 0.0 2.4 2 0 0 2 2 2 2 Archaeal ATPase AAA_17 PF13207.1 KUM63729.1 - 5.3e-05 24.0 0.3 0.041 14.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KUM63729.1 - 9.1e-05 21.6 0.1 0.03 13.4 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin ABC_ATPase PF09818.4 KUM63729.1 - 0.00013 20.7 0.0 0.28 9.7 0.0 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_25 PF13481.1 KUM63729.1 - 0.00019 20.9 0.1 0.27 10.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain Adeno_IVa2 PF02456.10 KUM63729.1 - 0.0003 19.5 0.1 0.058 12.0 0.0 2.2 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_5 PF07728.9 KUM63729.1 - 0.00047 19.9 0.1 1 9.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.13 KUM63729.1 - 0.0005 19.6 0.1 0.17 11.3 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 KUM63729.1 - 0.00054 20.1 0.1 1.7 8.8 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Septin PF00735.13 KUM63729.1 - 0.00085 18.4 0.0 0.36 9.8 0.0 2.3 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KUM63729.1 - 0.001 18.9 0.0 1.4 8.9 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase NB-ARC PF00931.17 KUM63729.1 - 0.0016 17.3 0.1 0.11 11.3 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain ATP_bind_1 PF03029.12 KUM63729.1 - 0.0018 17.8 0.7 0.73 9.3 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 KUM63729.1 - 0.0038 16.7 0.6 0.024 14.1 0.1 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family NACHT PF05729.7 KUM63729.1 - 0.0038 16.8 0.1 1.5 8.4 0.0 2.4 2 0 0 2 2 2 1 NACHT domain NTPase_1 PF03266.10 KUM63729.1 - 0.005 16.5 0.4 1.3 8.6 0.0 2.7 2 0 0 2 2 2 1 NTPase RNA12 PF10443.4 KUM63729.1 - 0.0053 15.2 0.2 0.31 9.5 0.0 2.3 2 0 0 2 2 2 1 RNA12 protein AAA_18 PF13238.1 KUM63729.1 - 0.0072 16.6 0.5 1.4 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 KUM63729.1 - 0.0073 15.9 0.4 0.61 9.6 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 KUM63729.1 - 0.0086 15.8 0.0 6.3 6.6 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain Dynamin_N PF00350.18 KUM63729.1 - 0.009 15.8 0.7 1.6 8.5 0.0 2.5 2 0 0 2 2 2 1 Dynamin family PRK PF00485.13 KUM63729.1 - 0.0099 15.4 0.1 0.13 11.8 0.0 2.2 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family IstB_IS21 PF01695.12 KUM63729.1 - 0.01 15.2 0.1 1.1 8.6 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein PduV-EutP PF10662.4 KUM63729.1 - 0.011 15.1 0.2 3 7.3 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 KUM63729.1 - 0.016 14.1 0.0 1.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 KUM63729.1 - 0.027 13.9 0.4 6.5 6.1 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.10 KUM63729.1 - 0.031 12.9 0.2 0.61 8.7 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_PrkA PF08298.6 KUM63729.1 - 0.034 12.8 0.0 0.44 9.1 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain AAA_35 PF14516.1 KUM63729.1 - 0.041 12.5 0.1 0.34 9.5 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_28 PF13521.1 KUM63729.1 - 0.043 13.7 0.8 9.8 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 KUM63729.1 - 0.053 13.0 0.0 7.1 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KUM63729.1 - 0.056 13.3 0.2 0.7 9.8 0.0 2.8 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit DEAD PF00270.24 KUM63729.1 - 0.067 12.6 0.0 1.6 8.1 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase TrwB_AAD_bind PF10412.4 KUM63729.1 - 0.12 10.9 0.4 13 4.2 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Pox_A32 PF04665.7 KUM63729.1 - 0.15 11.3 1.0 8.6 5.5 0.0 2.6 3 0 0 3 3 2 0 Poxvirus A32 protein AAA_15 PF13175.1 KUM63729.1 - 0.21 10.6 0.0 1.1 8.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain MFS_1 PF07690.11 KUM63731.1 - 1.2e-34 119.6 43.7 2.1e-33 115.4 30.3 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM63731.1 - 5.8e-13 47.9 21.1 1.5e-12 46.5 14.6 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KUM63731.1 - 1.1e-07 30.8 3.4 1.1e-07 30.8 2.3 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter DUF2781 PF10914.3 KUM63731.1 - 0.0048 16.6 1.9 0.016 14.9 1.3 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Peptidase_M19 PF01244.16 KUM63733.1 - 2.3e-101 338.9 0.2 2.7e-101 338.7 0.2 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) GDPD_2 PF13653.1 KUM63733.1 - 0.018 15.2 0.0 2.5 8.3 0.0 3.1 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family Hydantoinase_B PF02538.9 KUM63734.1 - 5.4e-183 608.9 0.0 7.6e-183 608.5 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KUM63734.1 - 7.8e-86 287.7 0.1 1.6e-85 286.7 0.1 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KUM63734.1 - 5e-53 179.1 0.0 9.9e-52 174.9 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region 2-Hacid_dh_C PF02826.14 KUM63735.1 - 9e-38 129.1 0.0 1.2e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KUM63735.1 - 7.1e-15 54.6 0.0 9.6e-15 54.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KUM63735.1 - 0.00081 19.2 0.1 0.0025 17.6 0.1 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KUM63735.1 - 0.038 14.4 0.1 0.071 13.5 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Helicase_C PF00271.26 KUM63736.1 - 1.3e-06 28.1 0.0 2.2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1125 PF06563.6 KUM63736.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1125) MFS_1 PF07690.11 KUM63738.1 - 3.4e-44 150.9 64.1 8.6e-44 149.6 40.6 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM63738.1 - 1.4e-14 53.2 31.8 2.3e-14 52.5 22.0 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KUM63738.1 - 4.8e-12 45.1 15.1 4.8e-12 45.1 10.4 2.9 1 1 1 3 3 3 1 Sugar (and other) transporter NAD_binding_8 PF13450.1 KUM63739.1 - 1.2e-12 47.6 0.3 1.2e-12 47.6 0.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KUM63739.1 - 1.7e-06 28.0 0.0 4.8e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KUM63739.1 - 3.7e-06 26.1 0.0 7.8e-06 25.0 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KUM63739.1 - 3.7e-06 26.3 6.9 0.00015 20.9 3.3 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KUM63739.1 - 8.3e-06 26.0 1.5 0.00073 19.6 0.5 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KUM63739.1 - 3.7e-05 22.7 2.6 6.2e-05 22.0 1.8 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KUM63739.1 - 5.6e-05 21.7 1.1 0.00022 19.8 0.5 1.9 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 KUM63739.1 - 8.3e-05 21.6 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KUM63739.1 - 0.00043 19.4 0.2 0.00093 18.3 0.2 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 KUM63739.1 - 0.0015 18.8 0.1 0.0049 17.2 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KUM63739.1 - 0.0023 17.0 0.0 0.0052 15.8 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.19 KUM63739.1 - 0.0029 16.7 0.1 0.0062 15.6 0.0 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase K_oxygenase PF13434.1 KUM63739.1 - 0.017 14.0 0.0 2.1 7.1 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KUM63739.1 - 0.042 13.6 0.9 1.7 8.4 0.1 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.17 KUM63739.1 - 0.25 10.1 1.1 0.37 9.5 0.7 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pkinase PF00069.20 KUM63740.1 - 1.7e-75 253.5 0.0 2e-75 253.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM63740.1 - 2.1e-36 125.3 0.0 2.7e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM63740.1 - 0.00017 20.6 0.3 0.0034 16.3 0.0 2.6 1 1 1 3 3 3 1 Kinase-like Kdo PF06293.9 KUM63740.1 - 0.013 14.5 0.5 0.029 13.4 0.0 1.7 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KUM63740.1 - 0.041 12.7 0.0 0.15 10.9 0.0 1.8 2 0 0 2 2 2 0 Seadornavirus VP7 APH PF01636.18 KUM63740.1 - 0.048 13.3 0.1 0.11 12.1 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Dicty_CAR PF05462.6 KUM63741.1 - 1.1e-06 27.7 15.2 5.4e-06 25.5 5.2 2.1 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor Git3 PF11710.3 KUM63741.1 - 0.0014 18.2 7.2 0.0014 18.2 5.0 1.8 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Dimer_Tnp_Tn5 PF02281.11 KUM63741.1 - 0.095 12.8 0.3 3.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Transposase Tn5 dimerisation domain Nnf1 PF03980.9 KUM63742.1 - 1.9e-29 101.8 3.1 3e-29 101.2 2.2 1.3 1 0 0 1 1 1 1 Nnf1 TPR_11 PF13414.1 KUM63743.1 - 4.5e-06 26.2 6.1 1.2 8.7 0.1 5.2 3 2 2 5 5 5 3 TPR repeat TPR_17 PF13431.1 KUM63743.1 - 0.1 12.8 0.5 13 6.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat X PF00739.14 KUM63744.1 - 0.11 12.4 6.8 0.18 11.7 4.7 1.4 1 0 0 1 1 1 0 Trans-activation protein X DUF2464 PF10240.4 KUM63744.1 - 0.3 10.3 3.8 0.39 10.0 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2464) DUF2638 PF10937.3 KUM63744.1 - 0.36 11.8 4.2 0.44 11.5 2.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2638) RAP1 PF07218.6 KUM63744.1 - 7.3 4.5 7.9 7.4 4.5 5.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NTF2 PF02136.15 KUM63745.1 - 9.4e-26 90.5 0.1 1.7e-25 89.6 0.1 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 KUM63745.1 - 1.8e-07 30.6 0.0 3.7e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM63745.1 - 0.00033 20.5 0.0 0.00071 19.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM63745.1 - 0.0019 17.9 0.0 0.0049 16.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KUM63745.1 - 0.053 13.3 0.0 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif SNF2_N PF00176.18 KUM63746.1 - 1.2e-10 40.6 0.0 1.7e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 KUM63746.1 - 0.069 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 HIRAN domain PNP_UDP_1 PF01048.15 KUM63747.1 - 3.1e-13 49.2 0.4 2.3e-12 46.4 0.3 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily zf-H2C2_2 PF13465.1 KUM63747.1 - 9.5e-08 31.9 1.0 9.5e-08 31.9 0.7 4.8 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KUM63747.1 - 0.0011 19.1 0.9 0.0011 19.1 0.6 4.9 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2 PF00096.21 KUM63747.1 - 0.0031 17.7 2.9 0.0031 17.7 2.0 4.6 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KUM63747.1 - 0.11 12.6 7.2 2.1 8.5 0.8 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DASH_Dad3 PF08656.5 KUM63747.1 - 0.14 11.8 1.1 0.46 10.2 0.4 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad3 Phage_GPL PF05926.6 KUM63747.1 - 0.16 11.7 4.5 0.29 10.9 0.8 2.5 2 0 0 2 2 2 0 Phage head completion protein (GPL) zf-met PF12874.2 KUM63747.1 - 0.31 11.2 4.3 8.4 6.7 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type MFS_1 PF07690.11 KUM63749.1 - 2.2e-42 145.0 27.1 2.2e-42 145.0 18.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KUM63749.1 - 0.0002 20.9 2.8 0.0002 20.9 2.0 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 SR-25 PF10500.4 KUM63750.1 - 0.00011 21.8 7.9 0.00011 21.7 5.5 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Peptidase_S49_N PF08496.5 KUM63750.1 - 0.035 13.8 5.0 0.035 13.8 3.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NST1 PF13945.1 KUM63750.1 - 0.064 13.3 5.9 0.078 13.0 4.1 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Rpn3_C PF08375.6 KUM63750.1 - 0.21 12.0 1.9 0.29 11.5 1.3 1.1 1 0 0 1 1 1 0 Proteasome regulatory subunit C-terminal TAF1D PF15333.1 KUM63750.1 - 0.25 11.1 10.2 0.28 10.9 7.1 1.1 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D Med19 PF10278.4 KUM63750.1 - 0.34 10.5 14.9 0.4 10.3 10.3 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 OAD_gamma PF04277.8 KUM63750.1 - 0.5 10.7 2.6 0.59 10.5 1.8 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain BLVR PF06375.6 KUM63750.1 - 2.3 8.0 17.6 2.9 7.6 12.2 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DUF1168 PF06658.7 KUM63750.1 - 2.5 7.6 16.5 3.1 7.3 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) DUF3899 PF13038.1 KUM63750.1 - 3.9 7.7 5.1 4.9 7.3 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) Astro_capsid PF03115.9 KUM63750.1 - 4 5.5 6.0 4.5 5.4 4.2 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor TSGP1 PF07771.6 KUM63750.1 - 4 7.3 11.8 5 7.0 8.2 1.2 1 0 0 1 1 1 0 Tick salivary peptide group 1 Cation_efflux PF01545.16 KUM63752.1 - 5.8e-63 212.6 0.5 6.8e-63 212.3 0.3 1.0 1 0 0 1 1 1 1 Cation efflux family TrkH PF02386.11 KUM63752.1 - 0.088 11.3 0.1 0.13 10.8 0.1 1.2 1 0 0 1 1 1 0 Cation transport protein FGGY_C PF02782.11 KUM63753.1 - 1.1e-31 109.9 0.0 1.8e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KUM63753.1 - 1.2e-23 83.6 0.0 3.5e-14 52.7 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Xpo1 PF08389.7 KUM63754.1 - 1.6e-40 138.3 0.6 1.2e-39 135.5 0.1 3.0 2 0 0 2 2 2 1 Exportin 1-like protein HEAT PF02985.17 KUM63754.1 - 0.0021 17.9 0.3 2.4 8.4 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat DUF2417 PF10329.4 KUM63755.1 - 0.0031 16.9 5.5 0.0037 16.7 3.8 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Tetraspannin PF00335.15 KUM63755.1 - 0.046 12.9 9.4 0.049 12.8 6.5 1.0 1 0 0 1 1 1 0 Tetraspanin family Claudin_2 PF13903.1 KUM63755.1 - 5.3 6.7 7.0 2.3 7.9 3.2 1.5 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction ADH_N PF08240.7 KUM63756.1 - 7.4e-21 73.9 0.4 1.2e-20 73.2 0.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM63756.1 - 1e-16 60.6 0.0 1.6e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KUM63756.1 - 7.9e-06 26.7 0.0 1.5e-05 25.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KUM63756.1 - 0.02 14.0 0.7 0.034 13.2 0.5 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KUM63756.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Nucleopor_Nup85 PF07575.8 KUM63757.1 - 2.3e-20 72.3 0.1 8.9e-11 40.7 0.0 3.1 3 1 0 3 3 3 2 Nup85 Nucleoporin Glyco_hydro_76 PF03663.9 KUM63760.1 - 2.5e-100 336.4 20.7 2.9e-100 336.2 14.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 BOF PF04076.8 KUM63761.1 - 0.036 13.9 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial OB fold (BOF) protein ADIP PF11559.3 KUM63762.1 - 9.3e-41 139.2 8.1 9.3e-41 139.2 5.6 2.6 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding APG6 PF04111.7 KUM63762.1 - 0.21 10.5 14.2 0.04 12.9 5.4 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 RasGAP_C PF03836.10 KUM63762.1 - 0.76 9.4 9.1 1.8 8.2 2.0 2.7 1 1 1 2 2 2 0 RasGAP C-terminus Spc7 PF08317.6 KUM63762.1 - 2 6.9 16.5 0.028 13.1 5.7 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Prominin PF05478.6 KUM63762.1 - 2.2 5.6 8.0 3.2 5.1 5.6 1.1 1 0 0 1 1 1 0 Prominin TBPIP PF07106.8 KUM63762.1 - 7.2 6.1 19.2 1 8.8 5.9 3.2 4 0 0 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Zn_clus PF00172.13 KUM63763.1 - 1.7e-08 34.2 10.1 2.8e-08 33.5 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KUM63763.1 - 1.2e-06 27.4 0.0 1.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aa_trans PF01490.13 KUM63764.1 - 1e-38 132.9 36.1 1.2e-38 132.6 25.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KUM63764.1 - 5.6e-05 22.1 15.7 5.6e-05 22.1 10.9 2.4 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family DUF2649 PF10854.3 KUM63764.1 - 0.7 10.0 5.9 0.89 9.7 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2649) DUF679 PF05078.7 KUM63764.1 - 1.5 8.4 7.1 0.73 9.4 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF679) GWT1 PF06423.7 KUM63764.1 - 1.9 8.5 13.1 0.075 13.1 2.3 3.1 2 2 0 2 2 2 0 GWT1 Rad51 PF08423.6 KUM63765.1 - 1.2e-123 411.0 0.1 1.6e-123 410.6 0.1 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 KUM63765.1 - 1.6e-10 40.5 0.0 2e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 KUM63765.1 - 5.4e-10 39.0 0.0 7.9e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 KUM63765.1 - 6.2e-10 39.0 1.8 2.2e-08 34.1 0.1 2.6 3 0 0 3 3 3 1 Helix-hairpin-helix domain KaiC PF06745.8 KUM63765.1 - 4.9e-09 35.6 0.0 1.1e-08 34.4 0.0 1.7 2 1 0 2 2 2 1 KaiC RNA_pol_A_CTD PF03118.10 KUM63765.1 - 0.14 11.5 0.0 0.31 10.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain zf-CCHC PF00098.18 KUM63766.1 - 6.4e-44 145.8 51.2 2.7e-07 30.1 0.6 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 KUM63766.1 - 3.2e-10 39.5 34.2 0.013 15.1 0.0 7.0 5 2 2 7 7 7 6 Zinc knuckle zf-CCHC_4 PF14392.1 KUM63766.1 - 9e-09 34.8 38.9 0.016 14.8 0.4 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_2 PF13696.1 KUM63766.1 - 0.079 12.4 0.2 0.079 12.4 0.1 7.1 4 2 3 7 7 7 0 Zinc knuckle zf-CCHC_6 PF15288.1 KUM63766.1 - 1.9 8.2 44.5 0.26 10.9 1.0 6.9 6 1 1 7 7 7 0 Zinc knuckle RRP7 PF12923.2 KUM63768.1 - 1.6e-31 109.0 8.2 1.6e-31 109.0 5.7 2.0 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 KUM63768.1 - 0.0069 15.9 0.0 0.93 9.1 0.0 2.8 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM63768.1 - 0.11 12.4 0.0 0.51 10.3 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Dak1_2 PF13684.1 KUM63768.1 - 0.13 11.1 0.9 2 7.2 0.0 2.3 2 1 0 2 2 2 0 Dihydroxyacetone kinase family Ribosomal_L14e PF01929.12 KUM63768.1 - 3.6 7.9 11.4 2 8.7 1.2 2.9 2 1 0 2 2 2 0 Ribosomal protein L14 Pro_isomerase PF00160.16 KUM63769.1 - 1.6e-37 129.0 0.0 2.4e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 KUM63769.1 - 6.2e-15 54.5 0.0 1.2e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM63769.1 - 1.9e-11 43.7 0.0 4e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM63769.1 - 5.3e-09 35.7 0.0 1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.13 KUM63770.1 - 8.4e-09 35.1 6.5 1.6e-08 34.3 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UDPGP PF01704.13 KUM63771.1 - 2.7e-57 194.1 0.0 3.9e-57 193.6 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 KUM63771.1 - 0.095 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain LysM PF01476.15 KUM63772.1 - 7.1e-12 45.0 0.0 0.065 13.1 0.0 4.3 4 0 0 4 4 4 4 LysM domain Glyco_hydro_18 PF00704.23 KUM63773.1 - 2e-74 251.0 5.7 3.7e-74 250.2 3.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 MU117 PF15474.1 KUM63773.1 - 7e-09 36.0 10.8 7e-09 36.0 7.5 4.8 4 1 1 5 5 5 1 Meiotically up-regulated gene family Ank_2 PF12796.2 KUM63774.1 - 5.3e-58 193.3 0.0 5.5e-19 68.2 0.0 4.9 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KUM63774.1 - 1.1e-31 106.9 2.4 3.1e-06 26.6 0.0 8.7 9 0 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.1 KUM63774.1 - 5.4e-26 88.0 3.8 0.00013 21.9 0.0 9.1 10 0 0 10 10 10 5 Ankyrin repeat Ank_4 PF13637.1 KUM63774.1 - 2.3e-23 82.0 0.8 6.3e-10 39.2 0.1 7.5 6 2 2 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM63774.1 - 5.3e-18 64.6 0.1 3.8e-08 33.3 0.1 6.4 5 1 2 7 7 7 4 Ankyrin repeats (many copies) DUF3447 PF11929.3 KUM63774.1 - 0.077 12.8 0.0 5.8 6.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) Sugar_tr PF00083.19 KUM63776.1 - 3.9e-10 38.9 12.2 4.1e-10 38.8 8.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Linker_histone PF00538.14 KUM63777.1 - 0.072 13.2 0.2 0.078 13.0 0.2 1.1 1 0 0 1 1 1 0 linker histone H1 and H5 family Glyco_transf_34 PF05637.7 KUM63778.1 - 4.8e-09 36.0 0.1 6.3e-05 22.5 0.0 2.3 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 KUM63778.1 - 0.044 13.1 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF273 Nucleotid_trans PF03407.11 KUM63779.1 - 1.6e-05 24.7 0.0 2.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.7 KUM63779.1 - 0.0028 17.2 0.1 0.016 14.7 0.1 2.0 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family IDO PF01231.13 KUM63780.1 - 5.7e-41 140.3 0.0 8.2e-41 139.8 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase TPR_11 PF13414.1 KUM63781.1 - 4.8e-14 51.7 5.5 2.2e-10 40.0 1.1 2.4 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KUM63781.1 - 3.5e-12 45.2 7.1 0.0037 17.0 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KUM63781.1 - 1.4e-07 31.9 6.2 0.00033 21.2 0.6 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KUM63781.1 - 2.6e-07 30.6 5.1 0.013 16.0 0.4 3.7 1 1 2 3 3 3 3 Tetratricopeptide repeat F-box PF00646.28 KUM63781.1 - 4.7e-07 29.2 0.1 1.8e-06 27.4 0.1 2.1 1 0 0 1 1 1 1 F-box domain TPR_19 PF14559.1 KUM63781.1 - 1.8e-06 28.1 3.9 0.012 15.8 0.3 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KUM63781.1 - 2.7e-06 26.7 7.6 0.067 12.8 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 KUM63781.1 - 9.1e-06 25.0 1.7 0.0063 16.2 0.1 3.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KUM63781.1 - 2.5e-05 24.1 5.9 0.0013 18.5 1.2 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KUM63781.1 - 0.00034 20.5 0.6 0.34 11.2 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat F-box-like PF12937.2 KUM63781.1 - 0.0004 20.0 0.1 0.00081 19.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like TPR_9 PF13371.1 KUM63781.1 - 0.00068 19.4 2.6 0.013 15.2 1.1 2.8 1 1 2 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KUM63781.1 - 0.0053 16.8 2.9 0.015 15.4 0.3 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 LRR_7 PF13504.1 KUM63781.1 - 0.007 16.3 1.4 18 6.0 0.0 6.5 8 0 0 8 8 5 0 Leucine rich repeat ChAPs PF09295.5 KUM63781.1 - 0.11 11.2 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) LRR_4 PF12799.2 KUM63781.1 - 0.26 10.9 8.0 2.3 7.9 1.3 4.9 3 2 0 3 3 3 0 Leucine Rich repeats (2 copies) TPR_6 PF13174.1 KUM63781.1 - 0.61 10.6 8.2 8.1 7.1 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_6 PF13516.1 KUM63781.1 - 2.7 8.3 7.5 3 8.1 0.0 4.8 6 0 0 6 6 3 0 Leucine Rich repeat Fis1_TPR_C PF14853.1 KUM63781.1 - 3.3 7.6 6.1 3.1 7.7 0.2 2.9 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Arrestin_N PF00339.24 KUM63782.1 - 5.2e-13 49.0 0.8 1.7e-08 34.3 0.0 2.9 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Abhydrolase_5 PF12695.2 KUM63783.1 - 0.03 14.0 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KUM63783.1 - 0.038 13.8 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family V-ATPase_G PF03179.10 KUM63784.1 - 4.3e-28 97.6 15.1 5.4e-28 97.3 10.5 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF2870 PF11069.3 KUM63784.1 - 0.069 13.1 5.3 0.11 12.5 3.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) DUF2201_N PF13203.1 KUM63784.1 - 0.18 10.9 3.4 0.21 10.7 2.4 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain CAF-1_p150 PF11600.3 KUM63784.1 - 0.24 10.7 15.3 0.31 10.4 10.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal HypD PF01924.11 KUM63784.1 - 0.29 9.8 1.6 0.36 9.5 1.1 1.1 1 0 0 1 1 1 0 Hydrogenase formation hypA family OmpH PF03938.9 KUM63784.1 - 2.2 8.2 13.0 2.9 7.8 9.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DivIVA PF05103.8 KUM63789.1 - 0.033 14.2 33.5 0.92 9.5 9.0 3.9 2 1 2 4 4 4 0 DivIVA protein IncA PF04156.9 KUM63789.1 - 0.08 12.5 38.2 1.7 8.1 7.1 3.3 1 1 2 3 3 3 0 IncA protein Fib_alpha PF08702.5 KUM63789.1 - 0.5 10.4 14.7 2.2 8.4 2.6 2.9 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF948 PF06103.6 KUM63789.1 - 1.1 9.2 10.9 2.6 7.9 0.5 3.5 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.7 KUM63789.1 - 3.9 7.2 19.4 6 6.6 2.7 3.3 2 1 1 3 3 3 0 Laminin Domain II Utp12 PF04003.7 KUM63789.1 - 5.6 6.9 9.9 0.86 9.5 2.9 2.6 2 1 1 3 3 3 0 Dip2/Utp12 Family Methyltransf_16 PF10294.4 KUM63790.1 - 9.9e-17 60.9 0.0 5.7e-16 58.4 0.0 1.9 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KUM63790.1 - 3.5e-06 27.5 0.0 6.2e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KUM63790.1 - 0.00029 20.2 0.0 0.00051 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KUM63790.1 - 0.0055 16.2 0.0 0.0082 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PTCRA PF15028.1 KUM63790.1 - 0.016 14.7 0.2 0.026 14.0 0.1 1.3 1 0 0 1 1 1 0 Pre-T-cell antigen receptor PrmA PF06325.8 KUM63790.1 - 0.018 14.1 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 KUM63790.1 - 0.019 14.7 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 KUM63790.1 - 0.04 13.9 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 KUM63790.1 - 0.057 12.4 0.0 0.094 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.1 KUM63790.1 - 0.064 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CLTH PF10607.4 KUM63791.1 - 2.3e-34 118.1 0.0 3.9e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 KUM63791.1 - 4.3e-23 81.7 0.3 6.5e-23 81.1 0.2 1.3 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 KUM63791.1 - 0.00015 21.3 0.2 0.00056 19.5 0.0 2.1 2 0 0 2 2 2 1 LisH DnaJ PF00226.26 KUM63792.1 - 1.1e-16 60.2 0.2 2e-16 59.4 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain INO80_Ies4 PF08193.6 KUM63793.1 - 3.2e-63 213.6 19.0 4e-63 213.3 13.2 1.1 1 0 0 1 1 1 1 INO80 complex subunit Ies4 Pyr_redox_2 PF07992.9 KUM63794.1 - 4e-25 88.8 0.0 9.3e-25 87.6 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KUM63794.1 - 2.5e-14 53.4 0.1 7.8e-12 45.4 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 KUM63794.1 - 9.7e-14 50.7 0.0 2.6e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 KUM63794.1 - 1.7e-06 28.2 0.0 0.00054 20.0 0.0 3.1 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 KUM63794.1 - 0.00018 21.1 0.0 0.00056 19.5 0.0 1.9 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain NAD_binding_9 PF13454.1 KUM63794.1 - 0.00073 19.3 0.2 1.3 8.7 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding Reductase_C PF14759.1 KUM63794.1 - 0.001 19.3 0.0 0.0029 17.8 0.0 1.8 1 0 0 1 1 1 1 Reductase C-terminal DUF1188 PF06690.6 KUM63794.1 - 0.0063 15.6 0.0 0.025 13.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1188) TrkA_N PF02254.13 KUM63794.1 - 0.0098 15.8 0.3 3.8 7.5 0.0 2.7 2 0 0 2 2 2 2 TrkA-N domain SHS2_Rpb7-N PF03876.12 KUM63795.1 - 3.4e-07 30.2 0.0 9.9e-07 28.8 0.0 1.8 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_polI_A34 PF08208.6 KUM63795.1 - 0.0069 16.0 23.8 0.0069 16.0 16.5 3.2 3 0 0 3 3 3 1 DNA-directed RNA polymerase I subunit RPA34.5 LicD PF04991.8 KUM63795.1 - 0.39 10.8 4.4 5.6 7.0 1.1 2.2 2 0 0 2 2 2 0 LicD family RTA1 PF04479.8 KUM63796.1 - 7.7e-54 182.5 10.2 7.7e-54 182.5 7.1 1.7 2 0 0 2 2 2 1 RTA1 like protein Ribosomal_S24e PF01282.14 KUM63797.1 - 2.7e-35 120.0 0.0 4.2e-35 119.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e BAR PF03114.13 KUM63803.1 - 4.3e-61 206.3 9.0 5.5e-61 206.0 6.3 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KUM63803.1 - 2.7e-13 49.0 0.0 5.3e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KUM63803.1 - 3.3e-12 45.7 0.0 5.7e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KUM63803.1 - 2.3e-09 36.5 0.2 5.3e-09 35.4 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain Vps5 PF09325.5 KUM63803.1 - 0.016 14.4 7.5 1.4 8.1 0.1 2.3 2 0 0 2 2 2 0 Vps5 C terminal like AHS1 PF02682.11 KUM63803.1 - 0.045 13.2 0.8 0.083 12.3 0.5 1.4 1 0 0 1 1 1 0 Allophanate hydrolase subunit 1 Zn_dep_PLPC PF00882.13 KUM63803.1 - 0.15 11.7 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Zinc dependent phospholipase C DUF4140 PF13600.1 KUM63803.1 - 0.37 11.2 3.7 2.6 8.5 1.0 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) YlqD PF11068.3 KUM63803.1 - 0.48 10.4 0.0 0.48 10.4 0.0 2.9 3 1 0 3 3 3 0 YlqD protein Uds1 PF15456.1 KUM63803.1 - 0.85 9.6 6.7 4.5 7.2 2.3 2.4 2 0 0 2 2 2 0 Up-regulated During Septation TMPIT PF07851.8 KUM63803.1 - 2.1 7.3 6.5 0.43 9.6 0.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein Opy2 PF09463.5 KUM63804.1 - 4.4e-09 36.2 23.5 8.7e-09 35.3 16.3 1.5 1 0 0 1 1 1 1 Opy2 protein Syndecan PF01034.15 KUM63804.1 - 0.00088 18.8 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain SKG6 PF08693.5 KUM63804.1 - 0.0021 17.3 1.6 0.0054 16.0 1.1 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1191 PF06697.7 KUM63804.1 - 0.0062 15.3 0.0 0.01 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) DUF912 PF06024.7 KUM63804.1 - 0.069 13.2 0.2 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) MSC PF09402.5 KUM63804.1 - 9.5 4.8 8.4 1.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain IDO PF01231.13 KUM63805.1 - 7.4e-96 321.1 0.0 8.4e-96 320.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 KUM63805.1 - 0.099 11.1 0.0 0.21 10.0 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) Aminotran_5 PF00266.14 KUM63806.1 - 7e-94 314.6 0.0 8.5e-94 314.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KUM63806.1 - 1.4e-06 27.7 0.0 2.2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KUM63806.1 - 0.00072 18.6 0.0 0.002 17.2 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family COesterase PF00135.23 KUM63807.1 - 2.3e-11 43.1 0.0 1.5e-08 33.8 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Palm_thioest PF02089.10 KUM63808.1 - 1.6e-56 191.2 0.0 2.1e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase HTH_18 PF12833.2 KUM63808.1 - 0.039 14.0 0.0 19 5.4 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain DUF915 PF06028.6 KUM63808.1 - 0.043 12.9 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_5 PF12695.2 KUM63808.1 - 0.07 12.8 0.0 2.5 7.8 0.0 2.2 1 1 1 2 2 2 0 Alpha/beta hydrolase family STE2 PF02116.10 KUM63810.1 - 1.5e-97 326.0 18.6 1.8e-97 325.7 12.9 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR UEV PF05743.8 KUM63811.1 - 4.8e-40 135.9 0.1 9.8e-40 135.0 0.1 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 KUM63811.1 - 7.6e-21 73.5 0.1 1.6e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.21 KUM63811.1 - 0.0073 15.7 0.2 0.0073 15.7 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KUM63811.1 - 0.15 11.9 2.4 0.28 11.0 0.0 2.2 2 0 0 2 2 2 0 RWD domain CsbD PF05532.7 KUM63812.1 - 1.2e-16 60.0 21.2 1.2e-10 40.8 4.0 3.3 3 0 0 3 3 3 3 CsbD-like Methyltransf_16 PF10294.4 KUM63813.1 - 1.2e-16 60.6 0.0 2e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 KUM63813.1 - 0.0011 18.6 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain F-box PF00646.28 KUM63816.1 - 0.022 14.3 1.7 0.27 10.9 0.0 2.9 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.2 KUM63816.1 - 0.03 14.0 0.0 0.087 12.5 0.0 1.8 1 0 0 1 1 1 0 F-box-like DUF3712 PF12505.3 KUM63817.1 - 5.7e-28 97.4 1.1 1.4e-27 96.2 0.8 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) DUF3328 PF11807.3 KUM63817.1 - 0.17 11.5 0.1 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) zf-C2H2_4 PF13894.1 KUM63819.1 - 0.014 15.6 15.2 0.14 12.5 0.2 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KUM63819.1 - 0.18 12.1 5.0 2.7 8.5 0.0 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type Med31 PF05669.7 KUM63822.1 - 1.9e-29 101.4 0.0 2.2e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 SOH1 Pal1 PF08316.6 KUM63823.1 - 2.8e-47 160.6 2.5 4.2e-46 156.8 1.7 2.6 1 1 0 1 1 1 1 Pal1 cell morphology protein COesterase PF00135.23 KUM63826.1 - 3.2e-110 369.3 0.2 3.8e-110 369.1 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KUM63826.1 - 8.8e-06 25.4 0.2 0.00013 21.5 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KUM63826.1 - 0.012 14.8 0.1 0.022 13.9 0.1 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family NDUF_B7 PF05676.8 KUM63827.1 - 4.8e-29 99.5 6.4 5.5e-29 99.3 4.4 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 KUM63827.1 - 0.0013 18.4 2.2 0.0016 18.1 1.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like GCS PF03074.11 KUM63828.1 - 1.3e-155 518.0 0.0 3.3e-155 516.7 0.0 1.6 1 1 0 1 1 1 1 Glutamate-cysteine ligase MCM PF00493.18 KUM63831.1 - 1.8e-122 408.3 0.0 2.7e-122 407.7 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 KUM63831.1 - 1.4e-35 122.6 40.1 1.4e-35 122.6 27.8 2.4 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 KUM63831.1 - 1.4e-16 61.1 0.0 3.8e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KUM63831.1 - 5.7e-08 32.1 0.1 6.3e-06 25.5 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KUM63831.1 - 0.00011 21.9 0.0 0.00023 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KUM63831.1 - 0.0023 17.4 0.1 0.018 14.5 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 KUM63831.1 - 0.015 14.9 0.1 0.16 11.5 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zn_ribbon_2 PF12674.2 KUM63831.1 - 0.032 14.5 0.3 0.096 13.0 0.2 1.8 1 0 0 1 1 1 0 Putative zinc ribbon domain Ank_2 PF12796.2 KUM63832.1 - 2.3e-12 47.0 1.3 6.2e-07 29.6 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KUM63832.1 - 9.4e-11 40.9 1.9 1.5e-08 34.0 0.1 3.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 KUM63832.1 - 1.7e-10 40.7 1.7 1.7e-06 28.1 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KUM63832.1 - 2.2e-10 40.7 0.9 5.1e-05 23.6 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM63832.1 - 4.2e-08 32.6 1.7 0.0029 17.6 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 KUM63832.1 - 5.8e-05 22.6 0.2 0.00057 19.4 0.0 2.6 3 0 0 3 3 3 1 KilA-N domain Med3 PF11593.3 KUM63832.1 - 2.8 7.0 11.3 0.26 10.4 4.3 1.7 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal KTI12 PF08433.5 KUM63834.1 - 5.2e-62 209.4 0.0 9.3e-62 208.6 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 KUM63834.1 - 0.00023 21.0 0.4 0.00051 19.9 0.3 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KUM63834.1 - 0.13 11.8 2.9 0.44 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Peptidase_C14 PF00656.17 KUM63835.1 - 1e-58 199.0 0.0 1.3e-58 198.6 0.0 1.1 1 0 0 1 1 1 1 Caspase domain DUF2236 PF09995.4 KUM63836.1 - 3.1e-45 154.3 4.1 3.6e-45 154.1 2.9 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) MDMPI_C PF07398.6 KUM63836.1 - 0.0093 16.5 0.0 0.024 15.2 0.0 1.8 1 1 0 1 1 1 1 MDMPI C-terminal domain MIS13 PF08202.6 KUM63837.1 - 2.2e-45 155.0 2.0 4.8e-45 153.9 1.4 1.6 1 0 0 1 1 1 1 Mis12-Mtw1 protein family AT_hook PF02178.14 KUM63837.1 - 0.037 13.6 14.7 0.68 9.8 1.9 3.6 2 0 0 2 2 2 0 AT hook motif DivIC PF04977.10 KUM63837.1 - 0.24 10.9 2.3 0.16 11.4 0.3 1.7 2 0 0 2 2 2 0 Septum formation initiator LCD1 PF09798.4 KUM63837.1 - 0.47 8.3 2.5 0.71 7.8 1.7 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein PS_Dcarbxylase PF02666.10 KUM63838.1 - 1.1e-50 171.7 0.0 1.7e-50 171.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase EF-hand_7 PF13499.1 KUM63838.1 - 0.0026 17.8 0.9 0.007 16.4 0.6 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KUM63838.1 - 0.011 15.0 0.3 0.04 13.2 0.1 2.2 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.1 KUM63838.1 - 0.039 13.8 0.1 0.22 11.5 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain EF-hand_5 PF13202.1 KUM63838.1 - 0.089 12.1 0.0 0.36 10.2 0.0 2.1 1 0 0 1 1 1 0 EF hand DUF1212 PF06738.7 KUM63840.1 - 4.5e-56 189.3 9.4 5.3e-50 169.5 0.4 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KUM63840.1 - 1.1e-31 109.4 8.2 1.1e-31 109.4 5.7 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3815) Pkinase PF00069.20 KUM63841.1 - 2.5e-63 213.6 0.0 3.4e-63 213.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM63841.1 - 2.8e-30 105.2 0.0 4.4e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM63841.1 - 0.01 14.7 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KUM63841.1 - 0.12 12.1 0.0 0.93 9.1 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF3949 PF13133.1 KUM63841.1 - 0.13 12.4 0.3 0.34 11.1 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3949) zf-UBR PF02207.15 KUM63842.1 - 1.8e-15 56.3 8.3 1.8e-15 56.3 5.8 3.5 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) C2 PF00168.25 KUM63843.1 - 9e-19 67.1 0.0 1.8e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain Sugar_tr PF00083.19 KUM63844.1 - 9.3e-90 301.3 12.0 1.2e-89 301.0 8.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM63844.1 - 1.6e-39 135.6 55.5 2.8e-35 121.6 19.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PEP_mutase PF13714.1 KUM63845.1 - 2.9e-48 164.1 0.9 3.3e-48 163.9 0.6 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 KUM63845.1 - 9.8e-19 66.9 0.3 1.4e-18 66.4 0.2 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.10 KUM63845.1 - 0.0094 15.1 0.2 0.11 11.6 0.0 2.0 2 0 0 2 2 2 1 Ketopantoate hydroxymethyltransferase DUF3605 PF12239.3 KUM63847.1 - 3.2e-63 212.2 1.2 4.1e-63 211.9 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Hist_deacetyl PF00850.14 KUM63848.1 - 1.4e-76 257.7 0.2 2e-76 257.2 0.2 1.1 1 0 0 1 1 1 1 Histone deacetylase domain SNF2_N PF00176.18 KUM63849.1 - 1e-52 178.8 0.0 1.5e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 KUM63849.1 - 7.2e-27 93.0 0.6 1.8e-26 91.8 0.0 2.1 2 0 0 2 2 2 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 KUM63849.1 - 1.2e-14 53.8 0.0 5.2e-13 48.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KUM63849.1 - 1.7e-05 24.7 0.0 0.00013 21.8 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Ssu72 PF04722.8 KUM63850.1 - 1.2e-81 272.7 0.0 1.4e-81 272.5 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Mito_fiss_reg PF05308.6 KUM63850.1 - 0.044 13.1 5.3 0.064 12.6 3.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 KUM63850.1 - 6.3 5.9 10.6 10 5.2 7.4 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Apc1 PF12859.2 KUM63851.1 - 0.038 14.2 0.1 0.094 12.9 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 Tom37_C PF11801.3 KUM63852.1 - 7.1e-36 123.6 0.0 1.2e-35 122.8 0.0 1.4 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 KUM63852.1 - 5.8e-26 90.5 0.3 1.6e-25 89.1 0.0 1.9 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 KUM63852.1 - 0.00088 19.1 0.1 0.0025 17.6 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PP2C PF00481.16 KUM63853.1 - 6.5e-47 160.0 0.2 7.7e-47 159.8 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KUM63853.1 - 6.6e-08 32.4 0.2 0.0025 17.5 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KUM63853.1 - 1e-05 25.0 0.1 9.6e-05 21.8 0.0 2.3 1 1 1 2 2 2 1 Protein phosphatase 2C Oxysterol_BP PF01237.13 KUM63854.1 - 2.2e-90 302.6 0.0 2.9e-90 302.3 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein DUF3868 PF12984.2 KUM63854.1 - 0.033 13.7 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3868) Ctr PF04145.10 KUM63855.1 - 5e-42 143.3 0.0 1e-41 142.3 0.0 1.5 1 1 0 1 1 1 1 Ctr copper transporter family DUF1673 PF07895.6 KUM63855.1 - 0.031 13.7 0.1 0.072 12.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) Oxidored_q3 PF00499.15 KUM63855.1 - 0.17 11.6 6.7 0.33 10.7 4.6 1.4 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF4407 PF14362.1 KUM63855.1 - 2.9 6.7 5.8 4.6 6.0 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RNase_PH PF01138.16 KUM63856.1 - 3.9e-33 114.5 0.3 9.6e-33 113.3 0.1 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Coiled PF05710.7 KUM63856.1 - 0.062 13.7 3.9 0.17 12.3 2.7 1.7 1 0 0 1 1 1 0 Coiled coil adh_short PF00106.20 KUM63857.1 - 2.3e-29 102.4 0.0 4.7e-29 101.4 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM63857.1 - 2.2e-23 83.2 0.0 2.8e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM63857.1 - 7.4e-10 38.7 0.0 1.1e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KUM63857.1 - 0.00027 20.6 0.1 0.0012 18.5 0.1 2.0 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 KUM63857.1 - 0.0023 16.9 0.0 0.0042 16.1 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 KUM63857.1 - 0.0026 17.2 0.0 0.0043 16.5 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.1 KUM63857.1 - 0.031 14.5 0.1 0.19 11.9 0.1 2.1 2 1 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_10 PF13460.1 KUM63857.1 - 0.074 13.0 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 NADH(P)-binding DUF952 PF06108.7 KUM63858.1 - 6e-26 90.1 0.0 7.6e-26 89.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) PAN_1 PF00024.21 KUM63859.1 - 0.069 12.9 0.0 0.089 12.5 0.0 1.2 1 0 0 1 1 1 0 PAN domain IMPDH PF00478.20 KUM63860.1 - 1.7e-129 431.7 3.4 2e-129 431.5 2.4 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 KUM63860.1 - 7.8e-17 60.8 0.0 1.2e-08 34.5 0.0 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 KUM63860.1 - 6.6e-07 28.7 3.3 0.0024 17.0 1.6 2.5 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 KUM63860.1 - 9.6e-06 24.6 0.7 1.9e-05 23.6 0.5 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 KUM63860.1 - 0.0036 16.6 3.3 0.074 12.3 2.3 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein Aldolase PF01081.14 KUM63860.1 - 0.015 14.4 1.1 0.042 13.0 0.1 2.1 2 0 0 2 2 2 0 KDPG and KHG aldolase Ribosomal_S21e PF01249.13 KUM63861.1 - 4.1e-41 138.8 0.0 5.6e-41 138.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S21e NUDIX PF00293.23 KUM63862.1 - 8.9e-13 48.0 0.0 2.3e-10 40.2 0.0 3.1 1 1 0 1 1 1 1 NUDIX domain DUF4473 PF14747.1 KUM63862.1 - 0.025 14.7 0.0 0.048 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) tRNA-synt_2d PF01409.15 KUM63863.1 - 2.7e-87 292.0 0.0 3.7e-87 291.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 KUM63863.1 - 0.00011 21.1 0.4 0.0023 16.7 0.0 2.9 4 0 0 4 4 4 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 KUM63863.1 - 0.00033 20.2 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_His PF13393.1 KUM63863.1 - 0.084 11.9 0.0 0.19 10.7 0.0 1.5 1 0 0 1 1 1 0 Histidyl-tRNA synthetase RasGAP_C PF03836.10 KUM63864.1 - 3.6e-45 153.1 4.1 1.6e-44 151.0 2.8 2.3 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 KUM63864.1 - 6.4e-38 130.3 0.0 2.2e-37 128.6 0.0 2.0 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 KUM63864.1 - 5.8e-11 41.0 53.7 0.8 9.5 0.1 15.5 15 0 0 15 15 15 9 IQ calmodulin-binding motif CH PF00307.26 KUM63864.1 - 5.2e-10 39.3 0.0 1.6e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain ENTH PF01417.15 KUM63865.1 - 9e-46 154.7 0.2 1.3e-45 154.2 0.2 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 KUM63865.1 - 0.00072 18.3 0.0 0.00099 17.8 0.0 1.2 1 0 0 1 1 1 1 ANTH domain Isochorismatase PF00857.15 KUM63866.1 - 2.9e-24 85.9 0.2 5.8e-24 84.9 0.1 1.5 1 1 0 1 1 1 1 Isochorismatase family FmdA_AmdA PF03069.10 KUM63867.1 - 9.1e-54 182.5 0.0 2.7e-27 95.4 0.0 2.5 1 1 1 2 2 2 2 Acetamidase/Formamidase family Syntaxin PF00804.20 KUM63868.1 - 9.4e-05 22.5 0.3 0.028 14.5 0.1 2.3 2 0 0 2 2 2 2 Syntaxin Apolipoprotein PF01442.13 KUM63868.1 - 0.032 13.7 0.2 0.35 10.3 0.0 2.1 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Barstar PF01337.13 KUM63868.1 - 0.081 12.7 0.5 0.36 10.6 0.1 2.3 1 1 1 2 2 2 0 Barstar (barnase inhibitor) DUF3618 PF12277.3 KUM63868.1 - 0.18 11.8 5.3 0.094 12.7 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) DUF948 PF06103.6 KUM63868.1 - 0.23 11.3 0.7 30 4.5 0.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) MARVEL PF01284.18 KUM63871.1 - 0.006 16.3 20.5 0.0079 16.0 14.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain HlyIII PF03006.15 KUM63871.1 - 0.07 12.5 9.4 0.093 12.1 6.5 1.1 1 0 0 1 1 1 0 Haemolysin-III related DUF4293 PF14126.1 KUM63871.1 - 1.1 9.1 6.7 0.59 10.0 2.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Fst_toxin PF13955.1 KUM63872.1 - 0.16 11.6 0.6 0.28 10.8 0.4 1.4 1 0 0 1 1 1 0 Toxin Fst, type I toxin-antitoxin system Vanabin-2 PF11437.3 KUM63872.1 - 4 7.4 18.3 13 5.8 12.7 1.7 1 1 0 1 1 1 0 Vanadium-binding protein 2 TIL PF01826.12 KUM63872.1 - 8.5 6.5 18.3 11 6.1 3.0 2.7 1 1 1 2 2 2 0 Trypsin Inhibitor like cysteine rich domain HMG-CoA_red PF00368.13 KUM63873.1 - 5.2e-154 512.4 4.0 6.7e-154 512.0 2.8 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 KUM63873.1 - 7.8e-52 175.0 0.4 1.6e-51 174.0 0.3 1.6 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 KUM63873.1 - 2.1e-13 49.9 3.5 1.1e-12 47.6 2.4 2.1 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KUM63873.1 - 1.5e-07 29.7 1.9 1.5e-07 29.7 1.3 1.4 2 0 0 2 2 2 1 Patched family DUF2304 PF10066.4 KUM63873.1 - 0.024 14.4 0.1 0.058 13.2 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) Pro_isomerase PF00160.16 KUM63875.1 - 2.5e-41 141.4 0.1 4.5e-41 140.6 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GIT_SHD PF08518.6 KUM63876.1 - 1.2e-25 88.5 2.6 3.5e-15 55.0 0.2 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT CENP-F_leu_zip PF10473.4 KUM63876.1 - 0.095 12.5 27.9 1.2 8.9 9.5 2.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF904 PF06005.7 KUM63876.1 - 0.8 10.0 32.3 3.1 8.1 3.0 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF904) DUF1843 PF08898.5 KUM63876.1 - 1.6 8.8 7.0 2.6 8.1 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) APG6 PF04111.7 KUM63876.1 - 1.9 7.4 29.0 0.013 14.5 12.4 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 UvrD_C PF13361.1 KUM63877.1 - 5.9e-74 249.6 0.0 7.9e-74 249.2 0.0 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 KUM63877.1 - 3.7e-62 210.4 3.8 1.6e-60 205.1 0.1 3.3 2 2 1 3 3 3 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 KUM63877.1 - 2e-14 53.6 0.0 5.6e-14 52.1 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 KUM63877.1 - 4.2e-12 45.6 0.1 6.7e-11 41.7 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KUM63877.1 - 8.4e-07 28.7 0.1 0.00018 21.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.1 KUM63877.1 - 9e-06 25.1 0.0 0.0002 20.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KUM63877.1 - 0.00029 20.5 0.9 0.0016 18.0 0.0 2.4 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.13 KUM63877.1 - 0.00053 19.5 0.8 0.21 11.0 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 KUM63877.1 - 0.0049 16.9 0.5 0.57 10.3 0.0 2.5 1 1 1 2 2 2 1 AAA domain Rrp15p PF07890.7 KUM63877.1 - 0.007 16.4 0.1 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 Rrp15p AAA_16 PF13191.1 KUM63877.1 - 0.018 15.0 1.5 0.064 13.2 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Sugar_tr PF00083.19 KUM63878.1 - 2.1e-49 168.3 29.6 7e-49 166.6 20.5 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM63878.1 - 2.6e-15 56.0 37.6 2.8e-08 32.8 10.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Zip PF02535.17 KUM63879.1 - 1.5e-56 191.7 10.7 1.7e-56 191.5 7.4 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Cyt-b5 PF00173.23 KUM63880.1 - 2.4e-15 56.0 0.0 3.9e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FKBP_C PF00254.23 KUM63881.1 - 1.4e-32 111.5 0.0 1.7e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF3277 PF11681.3 KUM63881.1 - 0.13 11.7 0.3 0.2 11.1 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3277) SH3_1 PF00018.23 KUM63882.1 - 7.3e-11 41.2 0.0 1.7e-10 40.1 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KUM63882.1 - 2.1e-10 40.0 0.1 4.2e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KUM63882.1 - 3.8e-08 32.6 0.0 7.4e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Peptidase_M20 PF01546.23 KUM63883.1 - 4.5e-30 104.5 0.0 7.1e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KUM63883.1 - 1.6e-13 50.4 0.0 2.4e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain PLDc PF00614.17 KUM63884.1 - 4.8e-14 51.6 0.5 1e-06 28.3 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KUM63884.1 - 4e-12 45.9 0.0 6e-07 29.2 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 KUM63884.1 - 4.7e-08 32.8 0.0 2.6e-07 30.4 0.0 2.4 2 1 0 2 2 2 1 PX domain Abhydrolase_6 PF12697.2 KUM63885.1 - 6.5e-07 29.4 0.0 1.1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM63885.1 - 1.3e-05 24.9 0.0 4e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Rnk_N PF14760.1 KUM63885.1 - 0.11 12.5 0.0 0.37 10.9 0.0 1.9 2 0 0 2 2 2 0 Rnk N-terminus Ribosomal_L18e PF00828.14 KUM63886.1 - 1.2e-13 51.5 0.0 1.3e-13 51.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Helicase_C_2 PF13307.1 KUM63888.1 - 1.7e-57 194.0 0.0 4.7e-57 192.5 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 KUM63888.1 - 4.4e-47 159.6 0.0 9.9e-47 158.5 0.0 1.6 1 0 0 1 1 1 1 DEAD_2 Lipoprotein_6 PF01441.14 KUM63888.1 - 0.085 12.7 2.9 0.19 11.5 0.3 2.3 2 0 0 2 2 2 0 Lipoprotein AKAP7_RIRII_bdg PF10470.4 KUM63888.1 - 0.087 12.6 3.8 8.8 6.2 0.0 3.2 3 1 0 3 3 3 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein YccV-like PF08755.6 KUM63889.1 - 2e-26 91.8 0.0 3.6e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.1 KUM63889.1 - 4.7e-10 39.1 0.0 1.2e-09 37.8 0.0 1.7 2 0 0 2 2 2 1 Transglutaminase-like superfamily F-box-like PF12937.2 KUM63889.1 - 6.2e-08 32.2 1.2 1.9e-07 30.6 0.8 1.9 1 0 0 1 1 1 1 F-box-like Elongin_A PF06881.6 KUM63889.1 - 0.02 15.2 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box PF00646.28 KUM63889.1 - 0.04 13.5 0.4 0.04 13.5 0.3 2.0 2 0 0 2 2 2 0 F-box domain Zn_clus PF00172.13 KUM63890.1 - 8.3e-09 35.2 13.2 1.4e-08 34.5 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 KUM63890.1 - 0.43 9.9 11.4 0.55 9.5 7.9 1.2 1 0 0 1 1 1 0 Vta1 like Aldose_epim PF01263.15 KUM63891.1 - 5.7e-60 202.9 0.0 6.3e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Ras PF00071.17 KUM63892.1 - 3e-34 117.7 0.0 5.7e-19 68.0 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KUM63892.1 - 8.6e-07 29.4 0.0 2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KUM63892.1 - 0.033 13.4 0.0 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 ADP-ribosylation factor family GTP_EFTU PF00009.22 KUM63892.1 - 0.043 13.2 0.0 0.62 9.4 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain LETM1 PF07766.8 KUM63894.1 - 8e-07 28.3 0.2 0.011 14.7 0.0 2.2 2 0 0 2 2 2 2 LETM1-like protein PAS_9 PF13426.1 KUM63895.1 - 1.3e-29 102.5 0.0 5.3e-20 71.7 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 KUM63895.1 - 3.5e-19 68.6 0.0 5.6e-12 45.5 0.0 3.7 3 0 0 3 3 3 3 PAS fold GATA PF00320.22 KUM63895.1 - 2.6e-14 52.2 7.2 7.5e-14 50.7 5.0 1.9 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.19 KUM63895.1 - 3.8e-12 46.0 0.0 0.00017 21.3 0.0 3.6 3 1 0 3 3 3 2 PAS fold PAS_4 PF08448.5 KUM63895.1 - 4.8e-09 36.2 0.0 0.0021 18.0 0.0 3.7 4 0 0 4 4 4 3 PAS fold PAS_11 PF14598.1 KUM63895.1 - 0.0001 22.2 0.0 0.032 14.2 0.0 3.2 3 0 0 3 3 3 1 PAS domain PAS_8 PF13188.1 KUM63895.1 - 0.001 18.8 0.0 0.082 12.8 0.0 2.6 2 0 0 2 2 2 1 PAS domain Cys_Met_Meta_PP PF01053.15 KUM63896.1 - 8.3e-36 123.0 0.0 1.1e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KUM63896.1 - 0.00025 20.1 0.0 0.00038 19.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Nrap PF03813.9 KUM63897.1 - 0 1136.8 0.0 0 1135.8 0.0 1.4 2 0 0 2 2 2 1 Nrap protein QRPTase_C PF01729.14 KUM63898.1 - 1.7e-46 157.8 0.3 7.8e-45 152.4 0.2 2.0 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 KUM63898.1 - 3.5e-25 87.6 0.0 1.1e-24 86.0 0.0 1.9 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Ribul_P_3_epim PF00834.14 KUM63898.1 - 0.099 11.7 0.1 0.58 9.2 0.0 2.1 1 1 2 3 3 3 0 Ribulose-phosphate 3 epimerase family Microtub_assoc PF07989.6 KUM63899.1 - 5.6e-24 83.7 9.4 5.6e-24 83.7 6.5 7.1 9 0 0 9 9 9 1 Microtubule associated Mto2_bdg PF12808.2 KUM63899.1 - 7.6e-21 73.9 31.7 8.5e-18 64.2 11.4 12.8 14 3 2 16 16 16 2 Micro-tubular organiser Mto1 C-term Mto2-binding region Reo_sigmaC PF04582.7 KUM63899.1 - 3.6e-05 23.1 3.4 3.6e-05 23.1 2.4 5.4 4 2 2 6 6 6 2 Reovirus sigma C capsid protein AHS1 PF02682.11 KUM63899.1 - 5.2 6.4 8.0 13 5.2 0.3 3.6 3 0 0 3 3 3 0 Allophanate hydrolase subunit 1 MRP-L20 PF12824.2 KUM63901.1 - 9.3e-63 211.0 4.5 1.1e-62 210.8 3.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.6 KUM63901.1 - 0.00078 19.3 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Neugrin DUF4158 PF13700.1 KUM63901.1 - 0.14 11.6 0.3 3.3 7.1 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4158) Fungal_trans PF04082.13 KUM63902.1 - 6e-08 31.8 0.0 1.1e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PhyH PF05721.8 KUM63903.1 - 0.0013 18.8 0.1 0.002 18.2 0.1 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 KUM63903.1 - 0.0018 16.8 0.1 0.0031 16.0 0.0 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1479) Sel1 PF08238.7 KUM63904.1 - 4.2e-20 71.7 17.6 6.1e-08 33.0 0.1 6.8 7 0 0 7 7 7 5 Sel1 repeat TPR_1 PF00515.23 KUM63904.1 - 0.00016 21.1 0.1 0.0011 18.4 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KUM63904.1 - 0.0088 15.6 0.2 0.0088 15.6 0.2 2.6 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.1 KUM63904.1 - 0.031 14.9 0.1 0.031 14.9 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KUM63904.1 - 0.052 14.2 3.3 0.15 12.7 0.0 3.6 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 KUM63904.1 - 0.094 12.6 0.0 0.094 12.6 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Sugar_tr PF00083.19 KUM63905.1 - 3.3e-85 286.3 25.5 3.9e-85 286.1 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM63905.1 - 4.8e-25 88.0 35.3 1.9e-19 69.5 12.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KUM63905.1 - 0.029 14.3 4.2 0.047 13.7 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1228) Complex1_LYR PF05347.10 KUM63906.1 - 4.6e-09 35.9 0.4 7.2e-09 35.3 0.3 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KUM63906.1 - 2.9e-06 27.3 0.2 4.2e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like DUF1151 PF06625.6 KUM63907.1 - 0.0045 16.7 4.7 0.0045 16.7 3.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1151) Auts2 PF15336.1 KUM63907.1 - 0.14 12.1 0.7 0.27 11.2 0.5 1.5 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein zf-CCCH PF00642.19 KUM63908.1 - 1.7e-11 43.5 10.7 8.7e-06 25.2 1.6 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KUM63908.1 - 0.86 9.7 16.0 2.4 8.3 2.7 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type TBPIP PF07106.8 KUM63909.1 - 1.9e-13 50.3 0.6 2.3e-13 50.0 0.4 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CENP-F_leu_zip PF10473.4 KUM63909.1 - 7.4e-06 25.8 2.0 1.1e-05 25.3 1.4 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 KUM63909.1 - 0.0021 17.6 1.7 0.0036 16.9 1.2 1.3 1 0 0 1 1 1 1 IncA protein Prefoldin_2 PF01920.15 KUM63909.1 - 0.0053 16.5 7.4 0.061 13.0 0.5 2.7 2 1 1 3 3 3 2 Prefoldin subunit MscS_porin PF12795.2 KUM63909.1 - 0.0055 16.0 1.4 0.0082 15.4 1.0 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Macoilin PF09726.4 KUM63909.1 - 0.0087 14.3 1.6 0.0092 14.3 1.1 1.1 1 0 0 1 1 1 1 Transmembrane protein HTH_39 PF14090.1 KUM63909.1 - 0.012 15.0 0.2 0.03 13.7 0.1 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain PspA_IM30 PF04012.7 KUM63909.1 - 0.021 14.2 3.4 0.036 13.4 1.8 1.7 1 1 0 1 1 1 0 PspA/IM30 family Cob_adeno_trans PF01923.13 KUM63909.1 - 0.033 13.9 0.9 0.14 11.8 0.3 1.8 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Coq4 PF05019.8 KUM63909.1 - 0.042 12.7 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Wbp11 PF09429.5 KUM63909.1 - 0.074 13.0 5.2 3.2 7.7 0.4 2.5 1 1 1 2 2 2 0 WW domain binding protein 11 DUF342 PF03961.8 KUM63909.1 - 0.093 11.1 0.3 0.12 10.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Herpes_BLRF2 PF05812.7 KUM63909.1 - 0.096 12.4 1.9 0.25 11.1 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Bacillus_HBL PF05791.6 KUM63909.1 - 0.098 12.0 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Snapin_Pallidin PF14712.1 KUM63909.1 - 0.11 12.7 1.1 0.21 11.9 0.7 1.4 1 0 0 1 1 1 0 Snapin/Pallidin DUF1192 PF06698.6 KUM63909.1 - 0.12 12.2 5.2 3.1 7.6 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) DUF2968 PF11180.3 KUM63909.1 - 0.12 11.7 1.9 0.16 11.3 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) YlqD PF11068.3 KUM63909.1 - 0.13 12.2 1.5 0.18 11.8 0.5 1.5 1 1 0 1 1 1 0 YlqD protein FlaC_arch PF05377.6 KUM63909.1 - 0.18 11.7 0.8 17 5.4 0.0 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4140 PF13600.1 KUM63909.1 - 0.19 12.1 6.8 3.1 8.2 0.5 2.4 2 1 1 3 3 2 0 N-terminal domain of unknown function (DUF4140) FlxA PF14282.1 KUM63909.1 - 0.25 11.2 1.9 0.44 10.5 1.3 1.4 1 1 0 1 1 1 0 FlxA-like protein MAD PF05557.8 KUM63909.1 - 0.28 9.2 7.9 0.01 13.9 1.3 1.6 2 1 1 3 3 3 0 Mitotic checkpoint protein CCDC-167 PF15188.1 KUM63909.1 - 0.31 11.0 6.1 0.84 9.6 0.8 2.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 GAS PF13851.1 KUM63909.1 - 0.37 9.9 5.7 0.72 9.0 4.0 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TPD52 PF04201.10 KUM63909.1 - 0.63 9.7 3.6 0.43 10.2 1.0 1.8 1 1 1 2 2 2 0 Tumour protein D52 family ADIP PF11559.3 KUM63909.1 - 1 9.2 5.1 1.1 9.1 1.0 1.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF904 PF06005.7 KUM63909.1 - 1 9.6 9.4 2.6 8.4 1.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DivIC PF04977.10 KUM63909.1 - 1.4 8.4 8.4 6.6 6.2 3.1 2.8 2 1 0 2 2 2 0 Septum formation initiator TMF_TATA_bd PF12325.3 KUM63909.1 - 1.4 8.6 5.6 9.9 5.9 0.5 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding TSC22 PF01166.13 KUM63909.1 - 1.5 8.8 4.1 4.3 7.3 0.0 2.5 2 1 1 3 3 2 0 TSC-22/dip/bun family APG6 PF04111.7 KUM63909.1 - 1.6 7.7 5.3 2.7 6.9 3.7 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 Uds1 PF15456.1 KUM63909.1 - 2.3 8.2 7.7 0.61 10.0 1.9 2.0 1 1 0 2 2 2 0 Up-regulated During Septation Histone PF00125.19 KUM63910.1 - 8.2e-26 89.9 0.0 1e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KUM63910.1 - 1.2e-05 25.2 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_C54 PF03416.14 KUM63911.1 - 6.9e-61 205.8 0.0 8e-61 205.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C54 Histone PF00125.19 KUM63912.1 - 2.9e-22 78.5 0.3 4.2e-22 78.0 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KUM63912.1 - 0.00023 21.1 1.1 0.0004 20.3 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KUM63912.1 - 0.00041 20.5 0.0 0.00069 19.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 KUM63912.1 - 0.02 14.3 0.1 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain DnaJ PF00226.26 KUM63913.1 - 1.6e-24 85.4 1.2 1.6e-24 85.4 0.8 2.9 4 0 0 4 4 3 1 DnaJ domain TPR_11 PF13414.1 KUM63913.1 - 1.3e-17 63.2 5.5 2e-06 27.3 0.0 5.5 4 2 1 6 6 6 4 TPR repeat TPR_2 PF07719.12 KUM63913.1 - 2.2e-16 58.3 1.7 0.086 12.8 0.0 8.2 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 KUM63913.1 - 7.6e-16 56.9 0.0 0.0011 18.4 0.0 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 KUM63913.1 - 8.5e-13 47.7 10.2 0.035 14.7 0.2 7.7 4 3 4 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 KUM63913.1 - 1.5e-10 40.7 10.2 0.00039 20.1 0.2 5.0 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 KUM63913.1 - 6.1e-10 39.2 6.7 0.00055 20.2 1.1 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KUM63913.1 - 3.6e-08 33.8 22.1 0.00085 19.9 0.7 6.4 5 1 3 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 KUM63913.1 - 3.6e-08 32.6 0.0 0.8 9.6 0.0 6.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 KUM63913.1 - 5.3e-08 32.8 1.2 11 6.7 0.0 7.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.1 KUM63913.1 - 6.7e-06 25.9 8.2 2 8.3 0.2 6.3 3 3 3 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 KUM63913.1 - 5.7e-05 22.9 0.7 0.26 11.5 0.0 6.0 6 1 0 6 6 6 1 Tetratricopeptide repeat RPT PF13446.1 KUM63913.1 - 0.0054 16.1 0.1 0.17 11.3 0.0 3.3 4 0 0 4 4 4 1 A repeated domain in UCH-protein Apc3 PF12895.2 KUM63913.1 - 0.048 13.7 10.7 1.7 8.8 0.4 4.8 3 2 3 7 7 6 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 KUM63913.1 - 0.07 13.0 0.7 4.8 7.1 0.1 3.6 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat 2-oxoacid_dh PF00198.18 KUM63914.1 - 2.9e-74 249.2 0.0 4.4e-74 248.6 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KUM63914.1 - 1.2e-18 66.5 2.0 2.7e-18 65.3 1.4 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 KUM63914.1 - 5.5e-05 22.4 1.9 0.00054 19.2 0.6 2.4 1 1 1 2 2 2 1 HlyD family secretion protein Tape_meas_lam_C PF09718.5 KUM63914.1 - 0.014 15.3 0.0 0.47 10.4 0.0 2.4 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Biotin_lipoyl_2 PF13533.1 KUM63914.1 - 0.023 14.3 0.5 0.81 9.4 0.1 2.4 1 1 1 2 2 2 0 Biotin-lipoyl like RnfC_N PF13375.1 KUM63914.1 - 0.032 13.9 0.2 0.25 11.0 0.1 2.2 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain GCV_H PF01597.14 KUM63914.1 - 0.041 13.5 0.3 0.089 12.4 0.2 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein DUF2360 PF10152.4 KUM63914.1 - 0.72 10.1 6.4 1.3 9.3 4.4 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DnaJ PF00226.26 KUM63915.1 - 1.6e-25 88.5 0.4 4.5e-25 87.1 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 KUM63915.1 - 3.8e-08 33.2 4.6 3.8e-08 33.2 3.2 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KUM63915.1 - 4.7e-06 26.6 3.7 4.7e-06 26.6 2.5 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KUM63915.1 - 1.2e-05 25.2 7.2 0.018 15.3 0.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 KUM63915.1 - 5.5e-05 23.2 6.1 0.063 13.3 2.8 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 KUM63915.1 - 0.026 14.8 4.4 2 8.9 0.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger LIM PF00412.17 KUM63915.1 - 0.068 13.2 2.0 6 7.0 0.0 2.4 2 0 0 2 2 2 0 LIM domain UPF0449 PF15136.1 KUM63915.1 - 0.096 12.9 2.4 0.34 11.1 1.7 2.1 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 Transcrip_act PF04949.8 KUM63915.1 - 0.18 11.4 6.3 0.33 10.5 0.0 3.0 3 0 0 3 3 3 0 Transcriptional activator zf-U1 PF06220.7 KUM63915.1 - 0.22 11.1 2.0 0.54 9.8 1.4 1.7 1 0 0 1 1 1 0 U1 zinc finger Cytochrome_C554 PF13435.1 KUM63915.1 - 0.76 9.8 7.5 0.71 9.9 1.8 2.5 2 0 0 2 2 2 0 Cytochrome c554 and c-prime Cytochrom_NNT PF03264.9 KUM63915.1 - 1.2 8.5 9.7 0.29 10.5 3.8 2.0 2 0 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region Cytochrom_c3_2 PF14537.1 KUM63915.1 - 1.3 9.3 6.1 0.89 9.9 1.6 2.3 2 0 0 2 2 2 0 Cytochrome c3 Cytochrome_C7 PF14522.1 KUM63915.1 - 2.2 7.9 6.0 0.97 9.1 1.0 2.3 2 0 0 2 2 2 0 Cytochrome c7 R3H PF01424.17 KUM63916.1 - 4.8e-13 48.5 0.0 1.1e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 KUM63916.1 - 1.1e-10 41.1 0.2 2.3e-10 40.1 0.2 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KUM63916.1 - 0.0011 18.7 0.2 0.0011 18.7 0.1 2.1 2 0 0 2 2 2 1 DExH-box splicing factor binding site PT PF04886.7 KUM63916.1 - 0.0028 16.9 1.5 0.0071 15.6 1.0 1.7 1 0 0 1 1 1 1 PT repeat PAP_assoc PF03828.14 KUM63917.1 - 0.031 14.2 0.0 0.34 10.8 0.0 2.3 1 1 0 1 1 1 0 Cid1 family poly A polymerase Glyco_transf_20 PF00982.16 KUM63918.1 - 8.2e-151 502.6 0.0 1.7e-150 501.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KUM63918.1 - 1.1e-90 302.6 0.0 1.7e-90 302.0 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase DEAD PF00270.24 KUM63919.1 - 7.8e-41 139.3 0.0 1.1e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM63919.1 - 8.8e-24 83.1 0.1 1.6e-23 82.3 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SMC_N PF02463.14 KUM63920.1 - 7.2e-25 87.5 0.0 2.1e-24 86.0 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KUM63920.1 - 1.9e-09 37.8 3.0 5.4e-06 26.5 0.5 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KUM63920.1 - 9.9e-09 35.8 37.4 9.9e-09 35.8 25.9 5.3 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.1 KUM63920.1 - 0.00012 21.5 0.0 0.00034 20.0 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 KUM63920.1 - 0.00023 20.3 5.0 0.00023 20.3 3.5 2.6 2 1 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.1 KUM63920.1 - 0.0026 17.6 0.5 0.011 15.6 0.0 2.3 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SMC_hinge PF06470.8 KUM63920.1 - 0.017 15.0 0.0 0.071 13.0 0.0 2.2 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain ABC_tran PF00005.22 KUM63920.1 - 0.081 13.2 0.2 0.081 13.2 0.1 5.3 3 2 0 3 3 3 0 ABC transporter UNC-50 PF05216.8 KUM63921.1 - 4.5e-85 284.5 4.1 5.9e-85 284.1 2.9 1.1 1 0 0 1 1 1 1 UNC-50 family YobH PF13996.1 KUM63921.1 - 7.9 6.4 6.6 0.46 10.4 0.6 1.9 2 0 0 2 2 2 0 YobH-like protein Sec7 PF01369.15 KUM63922.1 - 5.8e-42 143.5 0.0 1.2e-41 142.4 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 KUM63922.1 - 4.4e-20 72.0 0.3 1.4e-18 67.1 0.0 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain Tektin PF03148.9 KUM63922.1 - 0.07 11.6 0.1 0.11 11.0 0.1 1.2 1 0 0 1 1 1 0 Tektin family MFS_1 PF07690.11 KUM63923.1 - 5.9e-19 67.9 54.0 2.8e-17 62.4 31.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PP28 PF10252.4 KUM63924.1 - 7.3e-31 106.0 17.7 7.3e-31 106.0 12.3 3.2 3 0 0 3 3 3 1 Casein kinase substrate phosphoprotein PP28 DUF4637 PF15470.1 KUM63924.1 - 0.008 15.8 9.1 0.008 15.8 6.3 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF4637) RF-1 PF00472.15 KUM63925.1 - 3.3e-33 113.8 1.3 6.1e-33 113.0 0.9 1.4 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 KUM63925.1 - 6.4e-26 90.3 0.0 3.2e-25 88.0 0.0 2.1 2 0 0 2 2 2 1 PCRF domain Mito_carr PF00153.22 KUM63926.1 - 1.9e-48 162.1 6.0 6.2e-21 73.9 0.2 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein PCMT PF01135.14 KUM63927.1 - 3.8e-62 209.5 0.0 5.5e-62 209.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 KUM63927.1 - 3.2e-11 43.8 0.0 5.3e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM63927.1 - 3.3e-09 36.5 0.0 5.3e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KUM63927.1 - 5.7e-07 29.3 0.0 8.7e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM63927.1 - 7.5e-06 25.7 0.0 1.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KUM63927.1 - 2.2e-05 24.4 0.0 3.3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM63927.1 - 0.0015 18.8 0.0 0.0036 17.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM63927.1 - 0.0032 17.9 0.0 0.0055 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM63927.1 - 0.011 16.2 0.0 0.018 15.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 KUM63927.1 - 0.016 14.5 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW RrnaAD PF00398.15 KUM63927.1 - 0.049 12.6 0.0 0.068 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MTS PF05175.9 KUM63927.1 - 0.06 12.7 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 KUM63927.1 - 0.087 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_3 PF01596.12 KUM63927.1 - 0.093 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase FtsJ PF01728.14 KUM63927.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase E1-E2_ATPase PF00122.15 KUM63929.1 - 1e-58 198.1 0.0 2.4e-58 196.8 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KUM63929.1 - 4.4e-40 137.1 16.6 1.6e-34 119.0 4.3 3.5 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KUM63929.1 - 5.5e-31 108.6 0.0 1e-30 107.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KUM63929.1 - 8.2e-21 73.7 0.0 1.6e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KUM63929.1 - 2.4e-15 57.1 0.0 7e-15 55.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KUM63929.1 - 3.3e-11 42.4 0.3 7.6e-10 38.1 0.0 2.7 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KUM63929.1 - 2.1e-05 24.2 0.1 0.006 16.1 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase TPP_enzyme_N PF02776.13 KUM63930.1 - 1.4e-39 135.3 0.0 4e-39 133.8 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KUM63930.1 - 1.9e-23 82.7 0.0 1.2e-22 80.1 0.0 2.3 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KUM63930.1 - 3e-20 72.3 0.0 7.8e-20 71.0 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Inhibitor_I9 PF05922.11 KUM63931.1 - 0.0002 21.8 0.1 0.00023 21.6 0.1 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF2235 PF09994.4 KUM63932.1 - 2.5e-71 240.2 0.1 3.9e-71 239.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) PLDc_2 PF13091.1 KUM63933.1 - 3.3e-17 62.4 0.0 7.6e-11 41.8 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain Regulator_TrmB PF11495.3 KUM63933.1 - 0.0013 17.7 0.0 0.0023 16.9 0.0 1.3 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB PLDc PF00614.17 KUM63933.1 - 0.072 12.9 0.1 4.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Phospholipase D Active site motif MmgE_PrpD PF03972.9 KUM63934.1 - 1.4e-99 333.2 0.0 1.7e-99 333.0 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family BCDHK_Adom3 PF10436.4 KUM63935.1 - 1e-42 145.4 0.0 1.5e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KUM63935.1 - 1.6e-16 59.9 0.0 5.9e-16 58.1 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KUM63935.1 - 0.092 12.4 0.0 0.34 10.5 0.0 1.8 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glyco_hydro_2_N PF02837.13 KUM63936.1 - 3.1e-26 91.9 0.4 7e-26 90.7 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KUM63936.1 - 3e-12 46.0 0.0 9.7e-12 44.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 KUM63936.1 - 1.8e-08 34.8 0.0 4.1e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 tify PF06200.9 KUM63936.1 - 0.2 10.9 0.2 0.42 9.9 0.2 1.5 1 0 0 1 1 1 0 tify domain KH_1 PF00013.24 KUM63937.1 - 8.3e-29 99.0 7.5 9.6e-08 31.5 0.2 7.6 9 0 0 9 9 9 5 KH domain KH_3 PF13014.1 KUM63937.1 - 5.9e-23 80.0 3.1 0.00028 20.4 0.0 6.1 5 0 0 5 5 5 4 KH domain HATPase_c_5 PF14501.1 KUM63937.1 - 0.07 12.8 1.1 0.17 11.6 0.2 2.0 1 1 1 2 2 2 0 GHKL domain Chitin_synth_2 PF03142.10 KUM63938.1 - 7.7e-249 826.4 0.7 1.1e-248 825.9 0.5 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 KUM63938.1 - 2e-179 597.9 0.0 2.7e-179 597.4 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 KUM63938.1 - 9e-20 70.2 0.0 7e-14 51.3 0.0 3.3 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 KUM63938.1 - 1.6e-16 59.7 0.8 4.5e-15 55.1 0.6 2.7 3 0 0 3 3 3 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 KUM63938.1 - 4e-12 46.4 0.0 3.6e-10 40.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KUM63938.1 - 7.3e-11 42.1 7.3 7.3e-11 42.1 5.1 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 KUM63938.1 - 0.012 15.2 0.0 0.08 12.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KUM63938.1 - 0.031 13.5 0.0 0.074 12.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 21 AAA_22 PF13401.1 KUM63938.1 - 0.039 14.0 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KUM63938.1 - 0.051 13.5 0.1 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 KUM63938.1 - 0.065 12.4 0.0 0.17 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 KUM63938.1 - 0.17 12.1 0.4 0.84 9.9 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Chitin_synth_2 PF03142.10 KUM63939.1 - 6e-230 764.1 0.0 8e-230 763.7 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 KUM63939.1 - 8.4e-75 252.1 0.0 1.9e-74 251.0 0.0 1.5 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 KUM63939.1 - 1.1e-19 69.9 0.0 2.6e-09 36.7 0.0 2.7 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 KUM63939.1 - 1.4e-16 60.8 2.5 1.4e-16 60.8 1.8 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DEK_C PF08766.6 KUM63939.1 - 9.6e-16 57.3 0.5 2.9e-15 55.7 0.2 1.9 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 KUM63939.1 - 6.9e-14 52.1 0.0 5.2e-11 42.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KUM63939.1 - 2.5e-05 23.6 0.0 0.0001 21.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KUM63939.1 - 0.0023 17.6 0.0 0.031 13.9 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 PH_3 PF14593.1 KUM63939.1 - 0.068 13.0 0.1 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 PH domain Jiv90 PF14901.1 KUM63939.1 - 0.33 10.9 1.8 7.4 6.6 0.2 2.7 2 1 0 2 2 2 0 Cleavage inducing molecular chaperone DUF3712 PF12505.3 KUM63940.1 - 2e-22 79.5 0.1 3.9e-22 78.5 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) DUF1279 PF06916.8 KUM63940.1 - 0.0071 16.6 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DUF805 PF05656.9 KUM63940.1 - 0.046 13.5 0.1 0.087 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Mannosyl_trans3 PF11051.3 KUM63941.1 - 5e-62 209.7 0.0 7.4e-62 209.1 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Sugar_tr PF00083.19 KUM63944.1 - 5.8e-96 321.8 19.2 7.2e-96 321.4 13.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM63944.1 - 2.4e-30 105.4 43.5 4.1e-26 91.5 10.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KUM63944.1 - 0.001 17.2 0.5 0.001 17.2 0.3 2.0 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.8 KUM63944.1 - 0.0046 15.2 0.7 0.0046 15.2 0.5 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1989 PF09347.5 KUM63945.1 - 2.9e-53 179.7 0.0 3.3e-52 176.3 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1989) Aminotran_1_2 PF00155.16 KUM63946.1 - 9.2e-20 70.8 0.0 1.2e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KUM63946.1 - 0.00064 18.3 0.0 0.0012 17.4 0.0 1.3 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.12 KUM63946.1 - 0.2 10.6 0.1 1.3 7.9 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family MFS_1 PF07690.11 KUM63948.1 - 1e-24 86.9 26.8 1e-24 86.9 18.6 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM63948.1 - 1.5e-11 43.1 21.7 2.7e-11 42.4 15.0 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) L27 PF02828.11 KUM63948.1 - 0.073 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 L27 domain Dynactin PF12455.3 KUM63950.1 - 4.8e-89 297.9 11.1 4.8e-89 297.9 7.7 4.1 4 1 0 4 4 4 1 Dynein associated protein Reo_sigmaC PF04582.7 KUM63950.1 - 1.7 7.7 27.5 0.035 13.2 0.4 5.2 4 2 2 6 6 6 0 Reovirus sigma C capsid protein DUF3106 PF11304.3 KUM63951.1 - 0.097 13.0 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) Solute_trans_a PF03619.11 KUM63952.1 - 1.7e-102 342.4 6.5 2.1e-102 342.1 4.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha HAD_2 PF13419.1 KUM63954.1 - 1.1e-30 107.1 0.1 1.3e-30 106.9 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KUM63954.1 - 9.7e-08 32.6 0.0 1.7e-07 31.9 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KUM63954.1 - 9.2e-06 25.2 0.0 1.7e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 KUM63954.1 - 0.07 13.2 0.0 0.082 13.0 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase CDC45 PF02724.9 KUM63956.1 - 0.00023 19.3 10.4 0.00029 19.0 7.2 1.0 1 0 0 1 1 1 1 CDC45-like protein Nucleoplasmin PF03066.10 KUM63956.1 - 0.00053 19.5 15.3 0.00077 18.9 10.6 1.3 1 0 0 1 1 1 1 Nucleoplasmin RXT2_N PF08595.6 KUM63956.1 - 0.0028 17.4 5.7 0.0038 17.0 3.9 1.3 1 0 0 1 1 1 1 RXT2-like, N-terminal TRAP_alpha PF03896.11 KUM63956.1 - 0.029 13.3 15.3 0.032 13.2 10.6 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Daxx PF03344.10 KUM63956.1 - 0.03 12.8 20.5 0.034 12.6 14.2 1.0 1 0 0 1 1 1 0 Daxx Family Merozoite_SPAM PF07133.6 KUM63956.1 - 0.086 12.7 27.9 0.1 12.4 19.4 1.0 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Tim54 PF11711.3 KUM63956.1 - 0.09 11.3 10.1 0.096 11.2 7.0 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Ribosomal_L6e PF01159.14 KUM63956.1 - 0.15 12.2 2.2 0.17 12.1 1.5 1.1 1 0 0 1 1 1 0 Ribosomal protein L6e DUF2052 PF09747.4 KUM63956.1 - 0.15 11.9 16.3 0.17 11.7 11.3 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) FAM176 PF14851.1 KUM63956.1 - 0.23 11.1 10.2 0.28 10.8 7.1 1.1 1 0 0 1 1 1 0 FAM176 family YqfQ PF14181.1 KUM63956.1 - 0.25 11.3 12.4 0.28 11.2 8.6 1.1 1 0 0 1 1 1 0 YqfQ-like protein DUF2722 PF10846.3 KUM63956.1 - 0.28 10.1 3.9 0.27 10.2 2.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Nop14 PF04147.7 KUM63956.1 - 0.31 8.8 18.6 0.35 8.7 12.9 1.0 1 0 0 1 1 1 0 Nop14-like family PAXIP1_C PF15364.1 KUM63956.1 - 0.31 10.9 10.9 0.39 10.6 7.6 1.1 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Sigma70_ner PF04546.8 KUM63956.1 - 0.37 10.3 17.8 0.44 10.1 12.3 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region RNA_polI_A34 PF08208.6 KUM63956.1 - 0.37 10.4 13.6 0.41 10.2 9.4 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Lin-8 PF03353.10 KUM63956.1 - 0.39 9.9 10.4 0.42 9.8 7.2 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RR_TM4-6 PF06459.7 KUM63956.1 - 0.4 10.5 13.1 0.43 10.4 9.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HSP90 PF00183.13 KUM63956.1 - 0.41 8.9 21.0 0.49 8.7 14.6 1.0 1 0 0 1 1 1 0 Hsp90 protein DDHD PF02862.12 KUM63956.1 - 0.49 10.1 6.4 0.54 10.0 4.5 1.0 1 0 0 1 1 1 0 DDHD domain Prothymosin PF03247.9 KUM63956.1 - 0.51 10.5 33.2 0.66 10.1 23.0 1.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF585 PF04522.7 KUM63956.1 - 0.51 9.6 7.5 0.64 9.3 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF585) Packaging_FI PF14000.1 KUM63956.1 - 0.59 10.3 13.9 0.72 10.0 9.6 1.1 1 0 0 1 1 1 0 DNA packaging protein FI Myc_N PF01056.13 KUM63956.1 - 0.67 9.0 12.5 0.91 8.6 8.7 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Vfa1 PF08432.5 KUM63956.1 - 0.7 9.8 11.3 0.8 9.7 7.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF913 PF06025.7 KUM63956.1 - 0.71 8.5 3.3 0.71 8.5 2.3 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Cellulose_synt PF03552.9 KUM63956.1 - 0.77 7.9 2.8 0.82 7.8 1.9 1.0 1 0 0 1 1 1 0 Cellulose synthase CPSF100_C PF13299.1 KUM63956.1 - 0.79 9.8 4.4 0.85 9.7 3.1 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal AIF_C PF14721.1 KUM63956.1 - 0.81 9.9 4.1 0.86 9.8 2.8 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3530 PF12048.3 KUM63956.1 - 0.84 8.5 8.5 0.92 8.4 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Drc1-Sld2 PF11719.3 KUM63956.1 - 0.96 8.4 10.1 0.97 8.4 7.0 1.0 1 0 0 1 1 1 0 DNA replication and checkpoint protein TLP-20 PF06088.6 KUM63956.1 - 0.96 9.0 6.4 1.2 8.7 4.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) SDA1 PF05285.7 KUM63956.1 - 0.99 8.6 18.1 1.1 8.4 12.6 1.0 1 0 0 1 1 1 0 SDA1 DHHW PF14286.1 KUM63956.1 - 1 8.5 5.8 1.1 8.4 4.0 1.0 1 0 0 1 1 1 0 DHHW protein Tankyrase_bdg_C PF15327.1 KUM63956.1 - 1.1 9.4 5.3 1.2 9.3 3.6 1.1 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain Zip PF02535.17 KUM63956.1 - 1.1 8.1 3.9 1.2 8.0 2.7 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Pilt PF15453.1 KUM63956.1 - 1.3 8.6 8.0 1.3 8.6 5.5 1.0 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions DUF3306 PF11748.3 KUM63956.1 - 1.4 9.5 16.2 1.8 9.2 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Spore_coat_CotO PF14153.1 KUM63956.1 - 1.5 8.2 17.4 1.8 7.9 12.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO FYDLN_acid PF09538.5 KUM63956.1 - 1.6 9.3 14.1 2.1 8.9 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF3381 PF11861.3 KUM63956.1 - 1.7 8.1 20.5 2 7.8 14.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) WBS_methylT PF12589.3 KUM63956.1 - 1.7 9.1 6.6 2.4 8.7 4.6 1.2 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome Usp PF00582.21 KUM63956.1 - 1.7 8.8 5.3 2.1 8.5 3.7 1.4 1 0 0 1 1 1 0 Universal stress protein family Ycf1 PF05758.7 KUM63956.1 - 2 6.0 11.9 2.1 5.9 8.2 1.0 1 0 0 1 1 1 0 Ycf1 CENP-T PF15511.1 KUM63956.1 - 2 7.5 11.9 2.3 7.3 8.3 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Trypan_PARP PF05887.6 KUM63956.1 - 2.1 8.1 22.3 2.4 7.9 15.5 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF2890 PF11081.3 KUM63956.1 - 2.2 8.3 20.4 2.6 8.0 14.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) NPR3 PF03666.8 KUM63956.1 - 2.2 6.6 5.3 2.4 6.5 3.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1510 PF07423.6 KUM63956.1 - 2.7 7.3 18.8 3.2 7.0 13.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Presenilin PF01080.12 KUM63956.1 - 2.7 6.7 4.5 2.8 6.6 3.1 1.0 1 0 0 1 1 1 0 Presenilin Fmp27 PF10344.4 KUM63956.1 - 2.8 5.5 7.8 2.9 5.4 5.4 1.0 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Pox_Ag35 PF03286.9 KUM63956.1 - 3 7.3 14.4 3.7 7.0 10.0 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SAPS PF04499.10 KUM63956.1 - 3.5 6.1 8.0 3.7 6.0 5.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFIIF_alpha PF05793.7 KUM63956.1 - 3.5 5.8 21.6 3.8 5.7 14.9 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RNA_pol_Rpc4 PF05132.9 KUM63956.1 - 4.1 7.4 10.6 5.1 7.0 7.4 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF4628 PF15429.1 KUM63956.1 - 4.2 6.7 7.4 4.5 6.6 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) VID27 PF08553.5 KUM63956.1 - 5.1 5.1 16.1 5.5 5.0 11.2 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Pox_I3 PF04661.7 KUM63956.1 - 5.1 5.7 8.7 5.9 5.6 6.0 1.2 1 0 0 1 1 1 0 Poxvirus I3 ssDNA-binding protein Paf1 PF03985.8 KUM63956.1 - 5.5 5.6 22.7 6.7 5.3 15.8 1.0 1 0 0 1 1 1 0 Paf1 SID-1_RNA_chan PF13965.1 KUM63956.1 - 5.8 4.9 5.4 6.1 4.8 3.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RRN3 PF05327.6 KUM63956.1 - 6.1 4.8 12.1 6.6 4.7 8.4 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pox_RNA_Pol_19 PF05320.7 KUM63956.1 - 7.5 6.2 13.3 9.8 5.8 9.2 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit PI3K_1B_p101 PF10486.4 KUM63956.1 - 7.6 3.9 8.1 8.9 3.7 5.6 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Endonuc_Holl PF10107.4 KUM63956.1 - 8.5 6.0 9.0 11 5.7 6.2 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DDRGK PF09756.4 KUM63956.1 - 8.7 5.7 22.5 11 5.4 15.6 1.0 1 0 0 1 1 1 0 DDRGK domain Tom37_C PF11801.3 KUM63956.1 - 9.6 6.0 6.8 11 5.7 4.7 1.1 1 0 0 1 1 1 0 Tom37 C-terminal domain RVT_3 PF13456.1 KUM63957.1 - 0.00082 19.0 0.0 0.0014 18.3 0.0 1.4 1 1 0 1 1 1 1 Reverse transcriptase-like Phenyl_P_gamma PF09662.5 KUM63957.1 - 0.075 12.7 0.1 0.2 11.3 0.0 1.9 1 1 0 2 2 2 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) DUF4126 PF13548.1 KUM63960.1 - 2.4 7.5 8.8 0.96 8.8 3.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4126) Choline_transpo PF04515.7 KUM63961.1 - 1.1e-107 359.6 23.1 1.1e-107 359.6 16.0 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter Pex14_N PF04695.8 KUM63961.1 - 0.032 14.2 1.4 0.08 12.9 0.9 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NmrA PF05368.8 KUM63962.1 - 2.5e-12 46.5 0.0 3.4e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KUM63962.1 - 5.9e-12 45.9 0.5 9.3e-12 45.3 0.3 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KUM63962.1 - 4.5e-07 29.1 0.1 5.8e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 KUM63962.1 - 0.00026 20.9 0.4 0.00043 20.2 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 KUM63962.1 - 0.00031 21.0 0.1 0.00069 19.9 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 KUM63962.1 - 0.0011 18.4 0.2 0.0016 17.9 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KUM63962.1 - 0.002 17.8 0.6 0.0031 17.1 0.4 1.3 1 0 0 1 1 1 1 KR domain GFO_IDH_MocA PF01408.17 KUM63962.1 - 0.009 16.5 0.2 0.018 15.5 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 KUM63962.1 - 0.011 15.6 0.2 0.022 14.6 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 KUM63962.1 - 0.049 14.0 0.2 0.11 12.9 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ldh_1_N PF00056.18 KUM63962.1 - 0.067 13.0 0.7 0.17 11.7 0.5 1.7 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain TrkA_N PF02254.13 KUM63962.1 - 0.11 12.5 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain AA_permease PF00324.16 KUM63963.1 - 2.9e-101 339.1 51.3 3.6e-101 338.8 35.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KUM63963.1 - 5.1e-30 104.3 52.8 7.2e-30 103.8 36.6 1.1 1 0 0 1 1 1 1 Amino acid permease GMC_oxred_N PF00732.14 KUM63964.1 - 3.4e-27 95.3 0.0 2.8e-26 92.3 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KUM63964.1 - 3.5e-25 88.9 0.0 5.5e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Glyco_hydro_16 PF00722.16 KUM63966.1 - 2e-39 134.7 4.4 2e-39 134.7 3.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 MFS_1 PF07690.11 KUM63967.1 - 5.5e-38 130.5 13.9 5.5e-38 130.5 9.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily YfhO PF09586.5 KUM63967.1 - 0.0059 14.7 0.2 0.01 13.9 0.1 1.3 1 0 0 1 1 1 1 Bacterial membrane protein YfhO HATPase_c PF02518.21 KUM63968.1 - 1.8e-23 82.3 0.1 3.3e-23 81.5 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KUM63968.1 - 4.4e-19 68.5 0.5 8.4e-19 67.6 0.3 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KUM63968.1 - 1.5e-13 50.5 0.0 3.5e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 KUM63968.1 - 0.048 13.3 0.0 0.099 12.3 0.0 1.6 1 0 0 1 1 1 0 GHKL domain GAF_3 PF13492.1 KUM63968.1 - 0.082 13.0 0.1 1.2 9.2 0.0 2.6 2 1 0 2 2 2 0 GAF domain Adaptin_N PF01602.15 KUM63969.1 - 1.3e-91 307.5 12.3 2.2e-91 306.8 8.6 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.7 KUM63969.1 - 3.8e-62 208.1 0.8 9e-62 206.8 0.5 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.1 KUM63969.1 - 3.9e-62 207.7 0.0 1.5e-61 205.8 0.0 2.0 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.1 KUM63969.1 - 1.9e-12 47.2 10.2 1.5e-07 31.5 0.0 4.5 2 1 2 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 KUM63969.1 - 0.00014 22.2 1.9 0.012 16.0 0.0 4.6 3 1 2 5 5 5 2 HEAT-like repeat HEAT PF02985.17 KUM63969.1 - 0.00018 21.3 0.7 0.36 11.0 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.2 KUM63969.1 - 0.0006 19.7 10.7 0.0035 17.2 0.2 4.0 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 AP4E_app_platf PF14807.1 KUM63969.1 - 0.023 14.9 0.1 0.099 12.8 0.1 2.2 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Arm PF00514.18 KUM63969.1 - 0.06 13.1 1.8 0.81 9.6 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DAGK_cat PF00781.19 KUM63970.1 - 4.5e-22 77.8 0.0 7.5e-22 77.1 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain CRAL_TRIO PF00650.15 KUM63971.1 - 6.2e-22 77.7 0.0 1e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KUM63971.1 - 0.00022 21.2 0.0 0.00059 19.9 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Methyltrans_Mon PF14314.1 KUM63972.1 - 0.077 10.8 0.1 0.084 10.7 0.0 1.0 1 0 0 1 1 1 0 Virus-capping methyltransferase Thioesterase PF00975.15 KUM63975.1 - 2e-27 96.9 0.1 3.7e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 KUM63975.1 - 1.2e-09 38.2 0.3 2.7e-09 37.1 0.2 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 KUM63975.1 - 2.8e-05 24.1 0.1 5.3e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM63975.1 - 0.024 14.4 0.0 0.061 13.0 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Acetyltransf_1 PF00583.19 KUM63976.1 - 2.3e-10 40.3 0.0 3.3e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KUM63976.1 - 5.2e-08 32.9 0.0 7.9e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KUM63976.1 - 1.4e-06 28.3 0.1 1.7e-06 28.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KUM63976.1 - 0.001 19.0 0.0 0.0013 18.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NAD_binding_10 PF13460.1 KUM63977.1 - 1.1e-10 41.8 0.1 1.6e-10 41.3 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KUM63977.1 - 2e-05 23.9 0.6 6.1e-05 22.3 0.0 2.0 2 1 0 2 2 2 1 NmrA-like family Epimerase PF01370.16 KUM63977.1 - 0.00013 21.5 0.0 0.00085 18.8 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KUM63977.1 - 0.0096 14.6 0.0 0.18 10.4 0.0 2.4 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KUM63977.1 - 0.019 15.2 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KUM63977.1 - 0.03 13.2 0.1 1.9 7.3 0.0 2.3 1 1 1 2 2 2 0 Male sterility protein DapB_N PF01113.15 KUM63977.1 - 0.042 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Glyco_transf_90 PF05686.7 KUM63978.1 - 8.7e-15 54.3 1.3 3.5e-08 32.5 0.0 3.1 3 0 0 3 3 3 3 Glycosyl transferase family 90 HATPase_c PF02518.21 KUM63979.1 - 5.9e-20 71.0 0.5 1.1e-19 70.1 0.3 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KUM63979.1 - 1.2e-19 70.3 0.1 2.5e-18 66.0 0.2 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KUM63979.1 - 4.5e-12 45.7 0.1 1.6e-11 44.0 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 KUM63979.1 - 0.0048 16.5 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RabGAP-TBC PF00566.13 KUM63980.1 - 5.6e-39 133.8 0.0 2.6e-38 131.6 0.0 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF1604 PF07713.8 KUM63981.1 - 4.8e-37 125.6 1.8 4.8e-37 125.6 1.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.18 KUM63981.1 - 1.5e-06 27.8 4.4 2.5e-06 27.1 1.6 2.4 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 KUM63981.1 - 0.013 15.3 0.6 0.013 15.3 0.4 2.9 3 1 0 3 3 3 0 DExH-box splicing factor binding site DUF3431 PF11913.3 KUM63982.1 - 4.8e-61 206.0 0.0 5.3e-61 205.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Amino_oxidase PF01593.19 KUM63984.1 - 6.9e-29 101.2 0.0 1.1e-28 100.4 0.0 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Acetyltransf_3 PF13302.1 KUM63985.1 - 5e-37 127.2 0.0 5.9e-37 126.9 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KUM63985.1 - 1.1e-06 28.5 0.0 4e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KUM63985.1 - 0.0018 18.3 0.0 0.003 17.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KUM63985.1 - 0.017 15.0 0.0 0.036 13.9 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KUM63985.1 - 0.029 14.3 0.1 0.39 10.6 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_transf_90 PF05686.7 KUM63986.1 - 1.2e-13 50.5 7.8 4.1e-08 32.3 3.5 4.0 2 1 0 2 2 2 2 Glycosyl transferase family 90 HTH_42 PF06224.7 KUM63986.1 - 0.069 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain DUF4050 PF13259.1 KUM63988.1 - 0.48 10.3 3.9 1.7 8.5 3.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4050) Nop52 PF05997.7 KUM63989.1 - 3.9e-45 153.9 0.2 3.6e-37 127.9 0.5 2.1 2 0 0 2 2 2 2 Nucleolar protein,Nop52 HEAT_2 PF13646.1 KUM63989.1 - 0.046 14.0 0.1 2.1 8.6 0.0 2.5 2 1 0 2 2 2 0 HEAT repeats NOT2_3_5 PF04153.13 KUM63989.1 - 0.048 13.5 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family PGA2 PF07543.7 KUM63989.1 - 0.077 12.7 6.5 0.041 13.6 1.5 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 DUF1730 PF08331.5 KUM63989.1 - 0.11 12.2 0.1 0.38 10.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1730) Vac_ImportDeg PF09783.4 KUM63990.1 - 1.7e-71 239.3 1.4 2.1e-71 239.0 1.0 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mago_nashi PF02792.9 KUM63991.1 - 6.5e-76 252.8 0.7 7.8e-76 252.5 0.5 1.1 1 0 0 1 1 1 1 Mago nashi protein Transp_cyt_pur PF02133.10 KUM63992.1 - 1.1e-18 67.1 42.4 2.3e-18 66.0 29.4 1.6 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2236 PF09995.4 KUM63993.1 - 2.2e-12 46.7 0.0 1.5e-11 44.1 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) Tubulin PF00091.20 KUM63994.1 - 2e-69 233.7 0.0 3.5e-69 232.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KUM63994.1 - 1.7e-49 167.0 0.0 3.5e-49 166.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KUM63994.1 - 1.1e-05 25.4 0.0 2.8e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KUM63994.1 - 0.0037 16.7 0.0 0.0063 15.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.17 KUM63995.1 - 7.8e-15 54.2 0.0 4.5e-06 26.2 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM63995.1 - 1.1e-12 47.6 0.0 1.1e-08 34.7 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM63995.1 - 2.8e-08 33.6 0.0 0.0018 18.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ammonium_transp PF00909.16 KUM63997.1 - 1.5e-123 412.2 31.1 1.7e-123 412.0 21.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family RRM_1 PF00076.17 KUM63998.1 - 9.7e-13 47.5 0.0 1.4e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM63998.1 - 2.4e-08 33.8 0.0 3.5e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM63998.1 - 0.011 15.6 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 KUM63999.1 - 2.7e-66 223.4 0.0 4.1e-66 222.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM63999.1 - 2e-36 125.3 0.0 8.4e-36 123.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM63999.1 - 6.8e-06 25.2 0.1 6.4e-05 22.0 0.0 2.1 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KUM63999.1 - 0.0027 17.4 0.0 0.0065 16.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KUM63999.1 - 0.0081 15.0 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Phe_hydrox_dim PF07976.7 KUM64000.1 - 7e-16 58.2 0.0 1.6e-14 53.8 0.0 2.0 2 0 0 2 2 2 2 Phenol hydroxylase, C-terminal dimerisation domain EI24 PF07264.6 KUM64001.1 - 5.7e-05 22.6 4.5 0.00014 21.3 3.1 1.7 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) LRR_8 PF13855.1 KUM64002.1 - 1.1e-16 60.3 4.6 6.9e-09 35.3 0.8 3.7 3 0 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KUM64002.1 - 4.3e-16 58.1 11.3 8.1e-06 25.3 0.2 5.5 2 2 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KUM64002.1 - 5.4e-09 34.8 9.9 0.27 11.4 0.1 6.8 6 1 1 7 7 7 3 Leucine Rich Repeat LRR_7 PF13504.1 KUM64002.1 - 0.018 15.1 18.1 12 6.6 0.1 6.7 7 0 0 7 7 7 0 Leucine rich repeat LRR_6 PF13516.1 KUM64002.1 - 0.031 14.3 11.5 4.4 7.6 0.1 5.8 6 1 1 7 7 7 0 Leucine Rich repeat AflR PF08493.5 KUM64003.1 - 6.9e-05 22.0 1.3 8.7e-05 21.6 0.3 1.6 2 0 0 2 2 2 1 Aflatoxin regulatory protein Nuc_sug_transp PF04142.10 KUM64005.1 - 4.1e-22 78.4 11.4 6e-22 77.9 7.9 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 KUM64005.1 - 3.3e-05 24.0 4.4 3.3e-05 24.0 3.0 3.0 2 1 1 3 3 3 1 Multidrug resistance efflux transporter UPF0546 PF10639.4 KUM64005.1 - 0.071 12.9 5.6 0.042 13.6 0.8 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 HAUS4 PF14735.1 KUM64005.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 EamA PF00892.15 KUM64005.1 - 0.49 10.4 27.5 0.47 10.5 3.8 3.2 3 1 0 3 3 3 0 EamA-like transporter family VIT1 PF01988.14 KUM64005.1 - 1.7 8.1 12.3 0.053 12.9 3.4 2.2 2 0 0 2 2 2 0 VIT family TPT PF03151.11 KUM64005.1 - 3.3 7.3 23.4 0.25 10.9 2.2 2.7 2 2 0 2 2 2 0 Triose-phosphate Transporter family IQ PF00612.22 KUM64006.1 - 0.0074 15.8 0.4 0.0074 15.8 0.3 2.4 2 0 0 2 2 2 1 IQ calmodulin-binding motif Senescence PF06911.7 KUM64008.1 - 0.0034 17.1 4.9 0.0048 16.6 3.4 1.1 1 0 0 1 1 1 1 Senescence-associated protein SseC PF04888.7 KUM64008.1 - 0.69 9.1 4.2 0.84 8.9 2.9 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Lactamase_B PF00753.22 KUM64009.1 - 4.4e-26 91.7 1.6 5.5e-26 91.4 1.1 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KUM64009.1 - 0.00043 19.8 1.2 0.00066 19.2 0.8 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KUM64009.1 - 0.00044 19.9 1.1 0.0011 18.7 0.8 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain CAP59_mtransfer PF11735.3 KUM64011.1 - 3.6e-81 271.9 0.0 4.7e-81 271.5 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 PIG-L PF02585.12 KUM64012.1 - 2e-15 57.4 0.1 3.9e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Aminotran_4 PF01063.14 KUM64013.1 - 3.2e-35 121.6 0.0 4e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Arf PF00025.16 KUM64014.1 - 3.8e-65 218.3 0.0 4.2e-65 218.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KUM64014.1 - 1.7e-10 40.1 0.1 6.8e-07 28.2 0.0 2.3 2 1 0 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KUM64014.1 - 1.8e-08 33.8 0.0 2.4e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KUM64014.1 - 1.9e-07 31.5 0.0 2.5e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KUM64014.1 - 1e-06 28.6 0.0 1.4e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 KUM64014.1 - 1.3e-05 24.6 0.0 1.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KUM64014.1 - 6.6e-05 22.1 0.0 7.2e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KUM64014.1 - 0.0071 15.7 0.0 0.27 10.6 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.14 KUM64014.1 - 0.067 12.6 0.0 8.6 5.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 KUM64014.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF2457 PF10446.4 KUM64015.1 - 2.4e-154 514.4 31.1 2.4e-154 514.4 21.6 3.8 2 2 0 3 3 3 1 Protein of unknown function (DUF2457) Metallophos PF00149.23 KUM64017.1 - 1.2e-44 152.0 0.2 1.5e-44 151.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Fungal_trans PF04082.13 KUM64018.1 - 1.1e-15 57.2 0.7 1.7e-15 56.6 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Jacalin PF01419.12 KUM64019.1 - 1.3e-06 28.3 1.3 3.8e-05 23.5 0.6 1.9 1 1 1 2 2 2 2 Jacalin-like lectin domain MFS_1 PF07690.11 KUM64020.1 - 3e-31 108.4 31.9 3e-31 108.4 22.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.4 KUM64020.1 - 0.17 12.2 0.1 0.56 10.6 0.0 1.9 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) 60KD_IMP PF02096.15 KUM64020.1 - 0.84 9.2 6.3 0.43 10.1 1.6 2.4 3 0 0 3 3 3 0 60Kd inner membrane protein Lactonase PF10282.4 KUM64021.1 - 1.9e-86 290.3 0.0 2.3e-86 290.0 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller NinG PF05766.7 KUM64022.1 - 0.029 14.1 0.1 0.049 13.3 0.0 1.4 1 1 0 1 1 1 0 Bacteriophage Lambda NinG protein HTH_10 PF04967.7 KUM64022.1 - 0.082 12.5 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 HTH DNA binding domain HTH_Tnp_ISL3 PF13542.1 KUM64022.1 - 0.082 12.1 0.3 0.17 11.1 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Ribosomal_60s PF00428.14 KUM64022.1 - 1.1 9.6 7.7 0.54 10.6 3.7 1.7 1 1 0 1 1 1 0 60s Acidic ribosomal protein Myc_N PF01056.13 KUM64022.1 - 1.2 8.1 4.7 1.5 7.9 3.3 1.4 1 1 0 1 1 1 0 Myc amino-terminal region Glyco_hydro_76 PF03663.9 KUM64023.1 - 4.5e-133 444.2 18.1 5.8e-133 443.8 12.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Cloacin_immun PF03513.9 KUM64023.1 - 0.0061 16.5 0.4 0.015 15.3 0.2 1.8 2 0 0 2 2 2 1 Cloacin immunity protein ABC2_membrane_3 PF12698.2 KUM64023.1 - 0.072 12.1 0.0 0.18 10.8 0.0 1.6 2 0 0 2 2 2 0 ABC-2 family transporter protein Aldo_ket_red PF00248.16 KUM64025.1 - 3.7e-49 167.0 0.0 4.4e-49 166.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TEA PF01285.13 KUM64026.1 - 8.5e-140 466.7 0.2 1.1e-139 466.2 0.1 1.1 1 0 0 1 1 1 1 TEA/ATTS domain family RRM_1 PF00076.17 KUM64027.1 - 1.5e-66 219.9 3.5 8e-19 67.0 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM64027.1 - 7.8e-56 185.9 1.8 1.3e-13 50.6 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM64027.1 - 1.9e-36 123.6 0.1 9.2e-12 44.6 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KUM64027.1 - 1.3e-06 28.0 0.5 3 7.6 0.0 5.4 5 0 0 5 5 5 2 Limkain b1 Nup35_RRM_2 PF14605.1 KUM64027.1 - 0.00017 21.2 0.0 0.44 10.3 0.0 2.9 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Dynein_light PF01221.13 KUM64028.1 - 1.5e-39 133.8 1.5 2e-39 133.4 1.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Peptidase_C3 PF00548.15 KUM64028.1 - 0.002 17.9 0.0 0.0022 17.8 0.0 1.2 1 0 0 1 1 1 1 3C cysteine protease (picornain 3C) p450 PF00067.17 KUM64030.1 - 2.3e-48 164.8 0.0 3.6e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Hid1 PF12722.2 KUM64031.1 - 0.017 12.8 0.6 0.024 12.3 0.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Vezatin PF12632.2 KUM64034.1 - 6.4e-61 205.6 0.0 2.9e-60 203.4 0.0 1.9 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes PCNA_N PF00705.13 KUM64035.1 - 1.1e-54 183.3 2.6 2.2e-54 182.3 1.8 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 KUM64035.1 - 1e-51 174.1 0.0 2e-51 173.1 0.0 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 KUM64035.1 - 2.8e-08 33.1 0.1 4.2e-08 32.6 0.1 1.2 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 KUM64035.1 - 0.00043 19.3 0.2 0.011 14.6 0.0 2.2 2 0 0 2 2 2 1 Hus1-like protein Gly_transf_sug PF04488.10 KUM64036.1 - 5.7e-06 26.6 0.0 2.1e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KUM64036.1 - 0.033 12.6 0.0 0.049 12.1 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Sec61_beta PF03911.11 KUM64038.1 - 6.8e-19 67.3 0.6 1e-18 66.8 0.4 1.3 1 0 0 1 1 1 1 Sec61beta family SSF PF00474.12 KUM64039.1 - 2.5e-20 72.4 30.7 4.1e-20 71.7 21.3 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family NMT PF01233.14 KUM64040.1 - 5.5e-73 243.9 0.0 1.3e-72 242.6 0.0 1.6 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 KUM64040.1 - 3.7e-67 225.4 0.0 5.7e-67 224.7 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 KUM64040.1 - 2.1e-05 24.3 0.0 0.00032 20.5 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KUM64040.1 - 0.016 15.3 0.0 0.33 11.1 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KUM64040.1 - 0.033 14.2 0.0 0.066 13.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KUM64040.1 - 0.043 13.9 0.0 0.091 12.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2491 PF10679.4 KUM64040.1 - 0.052 12.5 0.3 3.3 6.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2491) Luciferase_N PF05295.6 KUM64040.1 - 0.12 12.1 0.2 0.41 10.4 0.1 1.9 2 0 0 2 2 2 0 Luciferase/LBP N-terminal domain Abhydrolase_6 PF12697.2 KUM64041.1 - 2e-10 40.9 0.1 4.3e-10 39.8 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM64041.1 - 2.8e-07 30.4 0.0 6.3e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KUM64041.1 - 0.00077 18.2 0.0 0.0013 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Amino_oxidase PF01593.19 KUM64042.1 - 7.4e-47 160.4 4.9 3.1e-45 155.0 3.4 2.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KUM64042.1 - 4.2e-15 55.5 0.3 1.4e-14 53.8 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KUM64042.1 - 6.2e-06 26.5 0.6 1.6e-05 25.2 0.4 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KUM64042.1 - 1.4e-05 25.3 1.2 0.00027 21.0 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KUM64042.1 - 2.4e-05 23.4 1.8 0.00022 20.2 0.8 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KUM64042.1 - 9.7e-05 22.3 1.2 0.14 12.0 0.4 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KUM64042.1 - 0.00026 19.5 1.5 0.00056 18.4 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KUM64042.1 - 0.00064 18.6 0.3 0.0011 17.9 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 KUM64042.1 - 0.0011 18.7 1.7 0.78 9.4 0.3 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.12 KUM64042.1 - 0.0025 16.9 0.2 0.0041 16.2 0.1 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 KUM64042.1 - 0.011 14.8 0.4 0.032 13.3 0.3 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KUM64042.1 - 0.017 14.1 0.3 0.036 13.1 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 KUM64042.1 - 0.058 13.0 0.6 0.058 13.0 0.4 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 KUM64042.1 - 0.23 10.2 2.6 0.15 10.8 0.4 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A MFS_1 PF07690.11 KUM64045.1 - 6.1e-28 97.5 61.9 2.9e-27 95.3 23.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM64046.1 - 1.4e-11 43.6 6.7 1.4e-11 43.6 4.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter NAD_binding_10 PF13460.1 KUM64047.1 - 2.6e-09 37.3 0.0 3.8e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KUM64047.1 - 1.3e-07 31.1 0.0 1.7e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KUM64047.1 - 0.035 14.0 0.5 0.071 13.0 0.3 1.6 1 1 1 2 2 2 0 short chain dehydrogenase Epimerase PF01370.16 KUM64047.1 - 0.037 13.4 0.0 1.5 8.2 0.0 2.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.13 KUM64048.1 - 9.5e-10 37.7 0.0 1.6e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Homeobox PF00046.24 KUM64049.1 - 8.2e-15 54.1 2.7 2.1e-14 52.8 1.8 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KUM64049.1 - 0.04 13.6 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain SNARE PF05739.14 KUM64050.1 - 2.3e-06 27.2 4.9 2.3e-06 27.2 3.4 2.2 2 0 0 2 2 2 1 SNARE domain BCIP PF13862.1 KUM64050.1 - 0.01 15.3 0.4 0.018 14.5 0.3 1.4 1 0 0 1 1 1 0 p21-C-terminal region-binding protein Lys-AminoMut_A PF09043.6 KUM64052.1 - 0.01 13.9 0.0 0.014 13.5 0.0 1.1 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase alpha subunit Aldo_ket_red PF00248.16 KUM64053.1 - 1.6e-51 174.7 0.0 2e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_23 PF13384.1 KUM64053.1 - 0.096 12.3 0.0 0.36 10.5 0.0 2.0 1 0 0 1 1 1 0 Homeodomain-like domain PHD PF00628.24 KUM64054.1 - 4.9e-11 42.1 7.3 4.9e-11 42.1 5.0 2.6 2 0 0 2 2 2 1 PHD-finger APH PF01636.18 KUM64054.1 - 0.0043 16.8 0.1 0.04 13.6 0.0 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family Sigma70_r2 PF04542.9 KUM64055.1 - 0.017 14.7 0.0 0.046 13.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-70 region 2 ADH_N PF08240.7 KUM64056.1 - 3.5e-26 91.0 4.4 6.1e-26 90.3 3.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM64056.1 - 1.5e-15 56.8 0.0 3.4e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KUM64056.1 - 0.00016 20.8 0.0 0.00028 20.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NADH_4Fe-4S PF10589.4 KUM64056.1 - 0.77 8.9 6.1 0.13 11.3 0.7 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Fungal_trans PF04082.13 KUM64057.1 - 5.5e-30 104.1 0.0 1e-29 103.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM64057.1 - 9.4e-11 41.4 12.9 1.7e-10 40.6 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 KUM64057.1 - 0.035 14.0 1.0 0.12 12.3 0.2 2.2 2 0 0 2 2 2 0 Gal4-like dimerisation domain 2OG-FeII_Oxy_3 PF13640.1 KUM64058.1 - 1.5e-05 25.4 0.0 2.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KUM64058.1 - 2.1e-05 24.7 0.0 7e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KUM64058.1 - 3.9e-05 23.2 0.5 8.5e-05 22.1 0.3 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sugar_tr PF00083.19 KUM64059.1 - 2.1e-103 346.3 29.4 2.4e-103 346.1 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM64059.1 - 1.6e-28 99.4 44.6 2.5e-27 95.5 16.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MRAP PF15183.1 KUM64059.1 - 0.52 9.9 2.5 1.3 8.6 0.3 2.3 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family Abhydrolase_6 PF12697.2 KUM64060.1 - 3.9e-28 98.8 0.1 4.5e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM64060.1 - 1.2e-10 41.2 0.0 1.9e-10 40.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KUM64060.1 - 0.0015 17.8 0.0 0.22 10.8 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Lys-AminoMut_A PF09043.6 KUM64060.1 - 0.077 11.1 0.0 0.11 10.5 0.0 1.2 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase alpha subunit AMP-binding PF00501.23 KUM64061.1 - 3.7e-80 269.3 0.0 6.1e-80 268.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KUM64061.1 - 5.4e-61 205.6 0.0 1.4e-60 204.2 0.0 1.8 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KUM64061.1 - 1.1e-32 113.2 9.1 2.4e-30 105.6 3.9 2.9 3 0 0 3 3 3 2 short chain dehydrogenase KR PF08659.5 KUM64061.1 - 1.5e-18 67.0 5.2 1.3e-15 57.5 2.9 2.5 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 KUM64061.1 - 1.3e-16 61.1 0.3 2.9e-16 59.9 0.2 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KUM64061.1 - 5.6e-16 58.6 0.0 6.4e-09 35.5 0.0 3.4 3 2 0 3 3 3 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KUM64061.1 - 8.4e-12 45.1 0.0 2e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 KUM64061.1 - 2.1e-09 36.4 0.1 0.00065 18.4 0.0 3.3 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 KUM64061.1 - 2.1e-07 31.7 0.6 2e-06 28.6 0.0 2.9 3 0 0 3 3 2 1 AMP-binding enzyme C-terminal domain RmlD_sub_bind PF04321.12 KUM64061.1 - 3.9e-07 29.2 0.8 2e-05 23.6 0.0 2.7 3 0 0 3 3 3 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KUM64061.1 - 0.00056 19.9 1.6 0.01 15.8 0.6 3.1 3 1 0 3 3 3 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KUM64061.1 - 0.0074 16.0 1.5 0.019 14.7 1.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 KUM64061.1 - 0.014 14.2 0.8 8.8 5.1 0.1 3.2 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein ApbA PF02558.11 KUM64061.1 - 0.017 14.6 0.1 0.038 13.4 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DFP PF04127.10 KUM64061.1 - 0.042 13.4 1.7 0.14 11.7 0.9 2.0 3 0 0 3 3 3 0 DNA / pantothenate metabolism flavoprotein NmrA PF05368.8 KUM64061.1 - 0.53 9.4 1.7 2.5 7.3 1.1 2.2 3 0 0 3 3 3 0 NmrA-like family Fungal_trans_2 PF11951.3 KUM64063.1 - 3.5e-40 137.7 1.9 4.2e-40 137.5 1.3 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Arf PF00025.16 KUM64064.1 - 4.6e-71 237.6 0.1 5.3e-71 237.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KUM64064.1 - 1.9e-13 50.1 0.0 2e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KUM64064.1 - 2.3e-12 46.3 1.4 5.8e-09 35.1 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KUM64064.1 - 1.5e-11 43.8 0.0 1.8e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KUM64064.1 - 5.5e-10 38.7 0.0 6.3e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KUM64064.1 - 2.9e-07 31.0 0.0 4.2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KUM64064.1 - 7.8e-05 22.1 0.0 0.00014 21.3 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KUM64064.1 - 8.7e-05 22.4 0.1 0.00018 21.4 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KUM64064.1 - 0.014 14.4 0.2 0.023 13.7 0.2 1.6 1 1 0 1 1 1 0 6-phosphofructo-2-kinase FeoB_N PF02421.13 KUM64064.1 - 0.016 14.4 0.4 0.029 13.6 0.2 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B Glycos_transf_1 PF00534.15 KUM64065.1 - 2e-16 59.9 0.0 4.2e-16 58.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KUM64065.1 - 8.7e-08 32.4 0.0 2.1e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KUM64065.1 - 2.4e-05 24.5 0.0 5.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Meth_synt_2 PF01717.13 KUM64066.1 - 2.2e-15 56.4 0.0 1.3e-09 37.5 0.0 2.4 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KUM64066.1 - 0.00045 19.6 0.0 0.013 14.7 0.0 2.7 3 0 0 3 3 3 1 Cobalamin-independent synthase, N-terminal domain zf-DHHC PF01529.15 KUM64068.1 - 5.8 6.2 10.8 6.3 6.1 7.5 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Tetraspannin PF00335.15 KUM64068.1 - 7.2 5.8 15.3 7.9 5.6 10.6 1.0 1 0 0 1 1 1 0 Tetraspanin family DUF2235 PF09994.4 KUM64069.1 - 1.3e-111 372.4 0.2 1.8e-111 371.9 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Hexapep PF00132.19 KUM64070.1 - 5.7e-07 28.7 8.8 0.015 14.7 0.5 4.6 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KUM64070.1 - 0.00011 21.6 0.3 0.00011 21.6 0.2 2.5 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase An_peroxidase PF03098.10 KUM64071.1 - 2e-91 306.9 0.0 8.5e-74 248.8 0.0 2.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.17 KUM64071.1 - 1.5e-06 27.0 0.0 6e-05 21.7 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Nucleo_P87 PF07267.6 KUM64072.1 - 0.3 9.7 8.9 0.4 9.3 6.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF2201_N PF13203.1 KUM64072.1 - 5.8 5.9 8.3 8.8 5.4 5.8 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DHDPS PF00701.17 KUM64073.1 - 5.2e-34 117.1 0.0 5.9e-27 94.0 0.0 2.0 2 0 0 2 2 2 2 Dihydrodipicolinate synthetase family GFO_IDH_MocA PF01408.17 KUM64074.1 - 5.1e-10 39.9 0.1 1.4e-09 38.5 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Pterin_bind PF00809.17 KUM64074.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Pterin binding enzyme PHD PF00628.24 KUM64076.1 - 9.7e-09 34.7 10.3 9.7e-09 34.7 7.2 1.7 2 0 0 2 2 2 1 PHD-finger ING PF12998.2 KUM64076.1 - 2.3e-05 24.6 0.0 4.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.1 KUM64076.1 - 0.074 13.2 1.8 0.16 12.1 1.3 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING-like PF08746.6 KUM64076.1 - 1.3 9.0 6.6 2.6 8.1 4.6 1.5 1 0 0 1 1 1 0 RING-like domain DUF4415 PF14384.1 KUM64076.1 - 3.9 7.6 5.9 38 4.5 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4415) Chal_sti_synt_C PF02797.10 KUM64077.1 - 1.4e-18 67.2 0.0 2.9e-18 66.2 0.0 1.7 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.14 KUM64077.1 - 1.8e-16 60.0 0.0 2.9e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain ACP_syn_III_C PF08541.5 KUM64077.1 - 1.7e-09 37.5 0.0 1.6e-08 34.4 0.0 2.2 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal FAE1_CUT1_RppA PF08392.7 KUM64077.1 - 0.0014 17.7 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein TENA_THI-4 PF03070.11 KUM64079.1 - 5.8e-16 58.8 0.0 6.4e-08 32.6 0.0 2.9 3 0 0 3 3 3 2 TENA/THI-4/PQQC family Fork_head PF00250.13 KUM64080.1 - 9.1e-38 128.2 1.2 1.8e-37 127.2 0.9 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 KUM64080.1 - 1.6e-08 34.4 0.0 4.1e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 FHA domain zf-C2H2 PF00096.21 KUM64081.1 - 1.7e-06 28.0 14.5 2.7e-05 24.2 1.9 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KUM64081.1 - 6.3e-06 26.2 7.0 1.7e-05 24.8 2.3 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KUM64081.1 - 0.0014 18.8 0.7 0.0014 18.8 0.5 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KUM64081.1 - 0.0031 17.5 0.7 0.0031 17.5 0.5 1.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 KUM64081.1 - 0.12 12.7 4.6 0.4 11.0 1.5 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger zf-Di19 PF05605.7 KUM64081.1 - 2.5 8.3 8.0 5.9 7.1 0.3 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding La PF05383.12 KUM64082.1 - 6.9e-20 70.6 0.2 1.2e-19 69.7 0.2 1.4 1 0 0 1 1 1 1 La domain RRN9 PF10680.4 KUM64082.1 - 0.036 13.8 1.9 3.5 7.4 0.1 3.1 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor NPR3 PF03666.8 KUM64083.1 - 1e-135 452.8 0.0 1e-135 452.8 0.0 2.5 3 0 0 3 3 3 1 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.6 KUM64083.1 - 0.0032 16.2 0.0 0.012 14.3 0.0 1.8 2 0 0 2 2 2 1 Nitrogen permease regulator 2 Mago-bind PF09282.5 KUM64083.1 - 6.2 6.4 7.9 0.49 9.9 1.4 2.2 2 0 0 2 2 2 0 Mago binding Band_7 PF01145.20 KUM64084.1 - 3.9e-31 108.3 0.9 7.3e-31 107.4 0.6 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KUM64084.1 - 0.0035 16.8 0.1 0.0097 15.4 0.0 1.8 2 1 0 2 2 2 1 SPFH domain-Band 7 family DUF913 PF06025.7 KUM64084.1 - 0.082 11.6 0.9 0.13 10.9 0.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) YchF-GTPase_C PF06071.8 KUM64088.1 - 1.2e-33 114.7 0.4 2.4e-33 113.7 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 KUM64088.1 - 1.9e-13 50.3 0.0 4.9e-12 45.8 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KUM64088.1 - 0.00071 18.8 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 KUM64088.1 - 0.0071 16.1 0.0 0.02 14.7 0.0 1.8 2 0 0 2 2 2 1 TGS domain SecA_PP_bind PF01043.15 KUM64088.1 - 0.014 15.7 0.0 0.03 14.7 0.0 1.6 1 0 0 1 1 1 0 SecA preprotein cross-linking domain AAA_14 PF13173.1 KUM64088.1 - 0.031 14.1 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF1955 PF09205.5 KUM64088.1 - 0.051 13.0 0.2 0.088 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) Hira PF07569.6 KUM64089.1 - 8.1e-83 276.9 0.0 1.6e-82 275.9 0.0 1.5 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 KUM64089.1 - 2e-40 135.2 21.1 1.5e-07 30.9 0.0 9.1 9 0 0 9 9 9 7 WD domain, G-beta repeat HIRA_B PF09453.5 KUM64089.1 - 7.5e-10 38.0 0.0 2.6e-09 36.3 0.0 2.0 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 KUM64089.1 - 0.00019 20.9 0.3 1.6 8.4 0.0 4.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat IKI3 PF04762.7 KUM64089.1 - 0.12 10.1 0.0 0.27 8.9 0.0 1.4 1 1 0 1 1 1 0 IKI3 family AMP-binding PF00501.23 KUM64090.1 - 2.3e-67 227.2 0.0 3.1e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KUM64090.1 - 9.3e-53 178.7 0.0 1.3e-52 178.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KUM64090.1 - 4.8e-15 55.6 0.0 1.7e-14 53.8 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KUM64090.1 - 1.1e-11 44.8 0.0 2.4e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 KUM64090.1 - 3.2e-09 35.8 0.0 8.7e-09 34.4 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 KUM64090.1 - 0.0085 17.0 0.2 0.028 15.3 0.2 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.10 KUM64090.1 - 0.053 12.4 0.0 0.085 11.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PUA PF01472.15 KUM64091.1 - 6.1e-14 51.5 0.1 8.3e-14 51.0 0.1 1.2 1 0 0 1 1 1 1 PUA domain RIC1 PF07064.8 KUM64093.1 - 2.3e-87 292.7 0.1 3.3e-87 292.1 0.1 1.2 1 0 0 1 1 1 1 RIC1 WD40 PF00400.27 KUM64093.1 - 0.076 12.9 0.9 7.6 6.5 0.0 4.3 5 0 0 5 5 5 0 WD domain, G-beta repeat TPR_11 PF13414.1 KUM64094.1 - 4.5e-21 74.2 8.5 7e-16 57.6 2.7 2.3 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KUM64094.1 - 6.5e-16 57.1 7.7 2.5e-06 26.8 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KUM64094.1 - 3.7e-14 51.4 10.7 4.3e-05 23.1 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 KUM64094.1 - 4.8e-09 35.3 4.6 0.00046 19.7 0.1 3.3 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KUM64094.1 - 1.5e-08 35.0 11.8 1.8e-06 28.4 4.6 2.4 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KUM64094.1 - 1.3e-07 31.2 4.4 0.0014 18.6 0.2 3.2 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KUM64094.1 - 2.7e-07 29.8 1.4 0.033 13.9 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KUM64094.1 - 8.2e-07 28.8 5.8 0.0019 18.0 1.3 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KUM64094.1 - 1e-05 25.6 8.0 0.083 13.5 1.7 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 KUM64094.1 - 2e-05 24.8 5.5 0.0016 18.7 2.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KUM64094.1 - 0.00027 20.7 2.8 0.0089 15.8 0.7 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.12 KUM64094.1 - 0.00059 20.1 1.2 0.0038 17.5 0.5 2.2 2 0 0 2 2 2 1 Bacterial transcriptional activator domain XPC-binding PF09280.6 KUM64094.1 - 0.0013 18.1 1.3 0.0013 18.1 0.9 1.9 2 0 0 2 2 2 1 XPC-binding domain Apc3 PF12895.2 KUM64094.1 - 0.035 14.2 1.7 0.51 10.5 0.1 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 KUM64094.1 - 0.17 11.8 5.5 22 5.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 KUM64094.1 - 0.18 11.6 4.1 1.7 8.5 0.1 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 KUM64094.1 - 0.24 11.9 7.8 0.31 11.5 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Tim44 PF04280.10 KUM64095.1 - 1.7e-33 115.6 0.0 6.1e-33 113.8 0.0 2.0 2 0 0 2 2 2 1 Tim44-like domain NifW PF03206.9 KUM64095.1 - 0.085 12.9 1.2 0.44 10.6 0.0 2.6 2 0 0 2 2 2 0 Nitrogen fixation protein NifW Ribosomal_S11 PF00411.14 KUM64096.1 - 5.1e-07 29.8 0.0 1.4e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S11 VPS9 PF02204.13 KUM64097.1 - 1.6e-17 63.3 0.1 7.2e-17 61.3 0.0 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.1 KUM64097.1 - 7.1e-17 61.0 0.4 8.6e-11 41.7 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KUM64097.1 - 7.9e-12 45.3 0.0 0.00028 21.1 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) PX PF00787.19 KUM64097.1 - 1.8e-07 30.9 2.1 1.8e-07 30.9 0.2 2.0 2 0 0 2 2 2 1 PX domain Ank_4 PF13637.1 KUM64097.1 - 5.6e-07 29.9 0.1 0.0038 17.7 0.0 4.0 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM64097.1 - 1.9e-06 27.5 0.2 9 6.8 0.0 5.8 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.25 KUM64097.1 - 8.1e-05 22.2 5.7 0.1 12.4 0.0 4.9 5 1 0 5 5 5 2 Ankyrin repeat Fanconi_A PF03511.9 KUM64097.1 - 0.037 13.8 0.1 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 Fanconi anaemia group A protein RNase_H PF00075.19 KUM64098.1 - 1e-12 48.5 0.0 1.3e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 KUM64098.1 - 0.0017 18.0 0.1 0.031 14.0 0.1 2.2 1 1 0 1 1 1 1 Reverse transcriptase-like DUF1049 PF06305.6 KUM64099.1 - 0.015 14.7 0.5 0.025 14.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Aldedh PF00171.17 KUM64100.1 - 1.8e-107 359.5 0.0 2e-107 359.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CHCH PF06747.8 KUM64101.1 - 6.8e-06 25.8 0.8 8.6e-06 25.5 0.6 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 KUM64101.1 - 0.02 14.9 2.0 0.065 13.2 1.5 1.6 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.8 KUM64101.1 - 0.02 14.8 3.7 1.3 9.1 0.2 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 KUM64101.1 - 0.12 12.2 1.0 0.18 11.6 0.7 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like adh_short PF00106.20 KUM64103.1 - 1.6e-11 44.4 0.0 1e-09 38.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KUM64103.1 - 7.2e-05 22.5 0.0 0.00014 21.5 0.0 1.5 2 0 0 2 2 2 1 KR domain Aldo_ket_red PF00248.16 KUM64104.1 - 2.1e-54 184.3 0.0 2.4e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GFA PF04828.9 KUM64106.1 - 1e-11 44.5 0.1 1.7e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Glyco_tranf_2_3 PF13641.1 KUM64109.1 - 4.5e-31 108.4 0.0 6.9e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KUM64109.1 - 3.5e-19 69.2 0.3 3.5e-19 69.2 0.2 2.4 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 KUM64109.1 - 2.7e-11 43.4 0.0 4.8e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KUM64109.1 - 2.1e-06 27.1 0.0 3.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Oxidored_FMN PF00724.15 KUM64110.1 - 8.5e-70 235.4 0.0 1.1e-69 235.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family UPF0029 PF01205.14 KUM64111.1 - 1.3 8.7 6.8 4.6 6.9 0.1 2.6 1 1 1 2 2 2 0 Uncharacterized protein family UPF0029 GPI-anchored PF10342.4 KUM64112.1 - 1e-18 67.6 2.6 1e-18 67.6 1.8 2.2 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Transaldolase PF00923.14 KUM64113.1 - 3.1e-31 108.5 0.0 3.7e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Transaldolase Alpha-amylase PF00128.19 KUM64115.1 - 8.5e-58 196.2 4.3 1.2e-57 195.6 3.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 KUM64115.1 - 3.4e-29 100.7 0.5 8.4e-29 99.4 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Alpha-amylase PF00128.19 KUM64116.1 - 2.6e-16 59.9 0.3 2.5e-15 56.6 0.3 2.5 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 KUM64116.1 - 1e-15 57.9 0.1 2e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 KUM64116.1 - 4.2e-06 26.9 0.0 1.1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 KUM64116.1 - 4.6e-06 26.1 0.0 9.8e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Big_5 PF13205.1 KUM64116.1 - 0.0069 16.9 0.1 0.034 14.7 0.1 2.2 1 0 0 1 1 1 1 Bacterial Ig-like domain Alpha-amylase PF00128.19 KUM64117.1 - 1.2e-30 106.9 0.0 3.3e-30 105.5 0.0 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 KUM64117.1 - 6.7e-08 30.7 0.3 0.0025 15.6 0.0 3.1 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 Transferase PF02458.10 KUM64120.1 - 9.5e-20 70.4 0.0 2.1e-19 69.3 0.0 1.5 1 1 0 1 1 1 1 Transferase family Condensation PF00668.15 KUM64120.1 - 0.0063 15.3 0.0 0.014 14.2 0.0 1.6 1 1 0 1 1 1 1 Condensation domain PTH2 PF01981.11 KUM64121.1 - 7.2e-38 128.8 0.2 2.8e-33 114.0 0.0 2.2 2 0 0 2 2 2 2 Peptidyl-tRNA hydrolase PTH2 CENP-B_dimeris PF09026.5 KUM64121.1 - 1.4 9.2 7.5 2.3 8.5 5.2 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NAD_binding_2 PF03446.10 KUM64122.1 - 3.5e-32 111.5 0.0 4.8e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KUM64122.1 - 6.3e-24 84.3 0.0 9.1e-24 83.8 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KUM64122.1 - 0.002 18.5 0.0 0.0044 17.4 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.10 KUM64122.1 - 0.058 12.1 0.0 0.08 11.6 0.0 1.1 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family MAF_flag10 PF01973.13 KUM64122.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF115 CoA_binding PF02629.14 KUM64122.1 - 0.11 13.0 0.0 2.1 8.8 0.0 2.4 2 0 0 2 2 2 0 CoA binding domain Aminotran_1_2 PF00155.16 KUM64123.1 - 1.2e-92 310.6 0.0 1.4e-92 310.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SART-1 PF03343.8 KUM64124.1 - 3.3e-167 557.5 58.7 3.8e-167 557.3 40.7 1.0 1 0 0 1 1 1 1 SART-1 family Pyridoxal_deC PF00282.14 KUM64125.1 - 2.3e-22 78.9 0.0 3.4e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KUM64125.1 - 8.4e-09 34.6 0.0 6.2e-08 31.7 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KUM64125.1 - 8.5e-07 28.2 0.0 1.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KUM64125.1 - 0.00023 20.3 0.0 0.00034 19.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF1744 PF08490.7 KUM64125.1 - 0.12 10.8 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) Cys_Met_Meta_PP PF01053.15 KUM64125.1 - 0.15 10.2 0.0 0.43 8.7 0.0 1.6 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Ribosomal_L30 PF00327.15 KUM64126.1 - 1.4e-15 56.5 0.2 1.8e-15 56.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e RBD PF02196.10 KUM64126.1 - 0.11 12.2 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 Raf-like Ras-binding domain HMGL-like PF00682.14 KUM64128.1 - 5.8e-70 235.6 0.7 9.5e-70 234.9 0.5 1.3 1 0 0 1 1 1 1 HMGL-like Pox_A_type_inc PF04508.7 KUM64129.1 - 0.053 13.3 1.0 0.55 10.1 0.1 3.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF155 PF02582.9 KUM64130.1 - 1.9e-57 193.9 0.0 3e-57 193.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF3753 PF12575.3 KUM64130.1 - 0.2 11.4 1.3 0.49 10.2 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Fungal_trans_2 PF11951.3 KUM64134.1 - 1.3e-31 109.5 0.1 1.7e-31 109.2 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM64134.1 - 2.6e-08 33.6 6.9 5.5e-08 32.5 4.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_3 PF00202.16 KUM64135.1 - 7.1e-85 284.8 0.0 8.3e-85 284.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KUM64135.1 - 0.00024 20.1 0.0 0.0014 17.6 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II TonB_2 PF13103.1 KUM64135.1 - 0.033 14.2 0.0 0.1 12.6 0.0 1.8 2 0 0 2 2 2 0 TonB C terminal MFS_1 PF07690.11 KUM64136.1 - 2.6e-31 108.6 56.4 2.3e-26 92.3 24.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM64136.1 - 1.1e-17 63.7 28.4 3e-17 62.3 19.7 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter LacAB_rpiB PF02502.13 KUM64136.1 - 0.024 14.3 0.4 0.042 13.4 0.3 1.3 1 0 0 1 1 1 0 Ribose/Galactose Isomerase DUF1228 PF06779.9 KUM64136.1 - 0.72 9.9 12.5 0.55 10.2 0.4 3.6 4 1 1 5 5 5 0 Protein of unknown function (DUF1228) MFS_1 PF07690.11 KUM64137.1 - 6.2e-31 107.3 16.6 9e-31 106.8 11.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Homeobox PF00046.24 KUM64139.1 - 3.7e-19 68.0 2.3 7.2e-19 67.1 1.6 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KUM64139.1 - 0.00089 18.9 0.9 0.0019 17.8 0.6 1.5 1 0 0 1 1 1 1 Homeobox KN domain GFO_IDH_MocA PF01408.17 KUM64140.1 - 2e-14 54.1 0.0 3.7e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 KUM64140.1 - 0.00047 20.5 0.0 0.0009 19.6 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 KUM64140.1 - 0.01 16.1 0.0 0.017 15.3 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Sugar_tr PF00083.19 KUM64141.1 - 8.8e-06 24.5 0.1 1.2e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM64141.1 - 0.0013 17.5 1.4 0.0021 16.8 1.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Fringe PF02434.11 KUM64142.1 - 1.4e-09 37.5 0.0 3.6e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.7 KUM64142.1 - 2.2e-06 27.1 0.0 1.7e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF604 SRP72 PF08492.7 KUM64143.1 - 3.2e-17 62.6 1.8 3.2e-17 62.6 1.2 2.4 2 0 0 2 2 2 1 SRP72 RNA-binding domain Apc3 PF12895.2 KUM64143.1 - 9.1e-06 25.7 10.9 0.86 9.7 3.2 4.8 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 KUM64143.1 - 3.5e-05 23.3 8.4 2.2 8.3 0.0 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 KUM64143.1 - 0.00018 21.3 12.1 2.6 8.0 0.1 5.8 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KUM64143.1 - 0.00027 21.2 22.0 1 9.7 0.4 6.9 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 KUM64143.1 - 0.00028 20.4 3.3 3.9 7.5 0.1 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 KUM64143.1 - 0.00035 20.9 24.2 1.2 9.9 0.6 9.2 6 2 4 10 10 10 1 Tetratricopeptide repeat TPR_6 PF13174.1 KUM64143.1 - 0.17 12.3 8.3 70 4.2 0.2 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 KUM64143.1 - 0.43 10.2 6.5 2.8 7.6 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF478 PF04334.7 KUM64144.1 - 0.32 10.8 5.5 0.16 11.8 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF478) zf-H2C2_2 PF13465.1 KUM64145.1 - 4.4e-20 70.9 30.5 2.9e-07 30.4 0.9 5.7 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 KUM64145.1 - 1.9e-19 68.7 27.3 2.5e-05 24.3 1.2 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KUM64145.1 - 7.7e-13 47.7 27.3 0.00046 20.3 3.1 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KUM64145.1 - 3.8e-05 23.6 8.4 0.23 11.6 0.1 4.4 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KUM64145.1 - 0.0012 18.9 16.0 0.012 15.7 0.2 4.2 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KUM64145.1 - 0.031 14.1 17.5 1.6 8.7 0.9 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger XPA_N PF01286.13 KUM64145.1 - 0.086 12.5 0.3 0.086 12.5 0.2 3.2 5 0 0 5 5 5 0 XPA protein N-terminal Yippee-Mis18 PF03226.9 KUM64145.1 - 0.41 10.7 2.7 7 6.7 0.2 2.3 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly C1_1 PF00130.17 KUM64145.1 - 1.4 8.6 6.9 0.91 9.3 0.8 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_4 PF07975.7 KUM64145.1 - 1.9 8.5 5.5 5.1 7.1 0.1 2.8 1 1 2 3 3 3 0 TFIIH C1-like domain DDE_Tnp_1_6 PF13751.1 KUM64145.1 - 2.3 8.2 7.7 0.24 11.4 2.1 1.7 2 0 0 2 2 2 0 Transposase DDE domain Zn-ribbon_8 PF09723.5 KUM64145.1 - 2.8 7.9 12.7 26 4.8 1.1 4.0 4 1 0 4 4 4 0 Zinc ribbon domain PEP_mutase PF13714.1 KUM64146.1 - 1.4e-32 112.8 1.0 1.5e-32 112.7 0.7 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ComA PF02679.10 KUM64146.1 - 0.027 13.5 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Eno-Rase_NADH_b PF12242.3 KUM64146.1 - 0.31 10.8 1.6 0.61 9.9 0.1 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TPR_12 PF13424.1 KUM64147.1 - 1.4e-06 28.1 4.1 0.035 14.0 0.2 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KUM64147.1 - 0.00054 19.6 2.7 0.71 9.9 0.5 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 KUM64147.1 - 0.0012 18.6 1.5 7.3 6.6 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KUM64147.1 - 0.01 15.4 0.3 3.2 7.5 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat NB-ARC PF00931.17 KUM64147.1 - 0.013 14.4 0.0 0.13 11.0 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain TPR_11 PF13414.1 KUM64147.1 - 0.014 15.0 0.5 1.9 8.1 0.1 3.3 3 0 0 3 3 3 0 TPR repeat AAA_35 PF14516.1 KUM64147.1 - 0.085 11.4 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain YqzH PF14164.1 KUM64147.1 - 0.089 12.7 0.3 15 5.5 0.1 3.2 3 0 0 3 3 3 0 YqzH-like protein vWA-TerF-like PF10138.4 KUM64148.1 - 0.00021 21.1 0.0 0.00033 20.5 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus E1-E2_ATPase PF00122.15 KUM64149.1 - 3.1e-21 75.4 0.5 7.5e-21 74.2 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KUM64149.1 - 1.2e-16 61.8 0.0 1.1e-15 58.6 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KUM64149.1 - 2.3e-14 54.0 0.1 1.5e-13 51.3 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KUM64149.1 - 1.3e-10 41.0 0.0 5.1e-10 39.1 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KUM64149.1 - 0.0021 17.6 0.1 0.0059 16.2 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3317 PF11779.3 KUM64149.1 - 6.1 6.3 11.5 0.28 10.6 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3317) RED_N PF07808.8 KUM64151.1 - 1e-07 31.4 0.7 2e-07 30.5 0.5 1.4 1 0 0 1 1 1 1 RED-like protein N-terminal region AA_permease_2 PF13520.1 KUM64154.1 - 3.6e-21 75.1 7.5 4.4e-21 74.9 5.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM64154.1 - 8.6e-09 34.2 8.9 1.2e-08 33.7 6.1 1.2 1 1 0 1 1 1 1 Amino acid permease DUF1212 PF06738.7 KUM64154.1 - 9.8 5.5 10.2 4.8 6.5 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) AA_permease_2 PF13520.1 KUM64155.1 - 7.9e-05 21.3 4.7 9.2e-05 21.1 3.2 1.0 1 0 0 1 1 1 1 Amino acid permease ABC2_membrane_5 PF13346.1 KUM64155.1 - 0.02 14.1 1.9 0.022 14.0 1.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein MFS_1 PF07690.11 KUM64156.1 - 3.9e-49 167.2 28.4 3.9e-49 167.2 19.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM64156.1 - 2.6e-18 65.8 15.0 2.8e-18 65.7 9.8 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3328 PF11807.3 KUM64156.1 - 2e-13 50.5 0.1 6.5e-13 48.8 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) TRI12 PF06609.8 KUM64156.1 - 1.9e-10 39.5 3.0 3.1e-10 38.8 2.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PTR2 PF00854.16 KUM64156.1 - 0.018 13.8 0.1 0.018 13.8 0.0 2.7 2 1 1 3 3 3 0 POT family Transgly_assoc PF04226.8 KUM64156.1 - 1.1 9.4 8.0 0.29 11.2 2.3 2.6 2 0 0 2 2 2 0 Transglycosylase associated protein OATP PF03137.15 KUM64156.1 - 3.4 5.6 8.4 3 5.7 1.2 2.9 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family AKAP7_NLS PF10469.4 KUM64157.1 - 2.3e-16 60.1 0.0 4e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Sec6 PF06046.8 KUM64158.1 - 1.6e-169 564.6 9.7 1.6e-169 564.6 6.7 1.4 2 0 0 2 2 2 1 Exocyst complex component Sec6 HrpB7 PF09486.5 KUM64158.1 - 0.085 12.7 9.1 0.28 11.1 6.3 1.9 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) MutS_III PF05192.13 KUM64158.1 - 0.16 11.6 4.9 10 5.8 2.2 3.0 2 1 0 2 2 2 0 MutS domain III DUF572 PF04502.8 KUM64158.1 - 5.4 6.1 7.2 9.8 5.2 5.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Steroid_dh PF02544.11 KUM64159.1 - 6.2e-13 48.7 0.8 6.2e-13 48.7 0.5 2.1 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase BRI3BP PF14965.1 KUM64159.1 - 0.0075 15.6 0.6 0.0075 15.6 0.4 3.0 3 0 0 3 3 3 1 Negative regulator of p53/TP53 DUF3492 PF11997.3 KUM64159.1 - 0.018 14.5 0.1 0.026 14.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) YbgT_YccB PF08173.6 KUM64159.1 - 1.7 8.5 8.7 4.6 7.1 6.1 1.8 1 0 0 1 1 1 0 Membrane bound YbgT-like protein 2OG-FeII_Oxy_2 PF13532.1 KUM64160.1 - 3e-14 53.3 0.0 8.1e-14 51.8 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KUM64160.1 - 8.8e-07 29.1 0.0 2.3e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KUM64160.1 - 0.12 12.9 0.0 1.8 9.1 0.0 2.5 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Stb3 PF10330.4 KUM64162.1 - 7.2e-39 131.3 0.0 1.2e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein Kri1_C PF12936.2 KUM64163.1 - 2.5e-30 104.2 1.0 2.5e-30 104.2 0.7 3.6 2 2 1 3 3 3 1 KRI1-like family C-terminal Kri1 PF05178.7 KUM64163.1 - 1.4e-27 95.8 17.3 1.4e-27 95.8 12.0 5.1 5 0 0 5 5 5 1 KRI1-like family LicD PF04991.8 KUM64163.1 - 0.00014 22.0 11.0 0.00027 21.1 2.0 2.5 2 0 0 2 2 2 2 LicD family Mito_carr PF00153.22 KUM64164.1 - 1.9e-66 219.8 5.3 3.2e-23 81.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sen15 PF09631.5 KUM64165.1 - 4.2e-14 52.6 0.0 3.7e-12 46.3 0.0 2.3 1 1 0 1 1 1 1 Sen15 protein PH PF00169.24 KUM64166.1 - 4e-10 39.8 0.2 2.6e-09 37.1 0.0 2.5 2 0 0 2 2 2 1 PH domain GRAM PF02893.15 KUM64166.1 - 0.0063 16.0 0.0 0.019 14.4 0.0 1.8 1 0 0 1 1 1 1 GRAM domain bPH_3 PF14470.1 KUM64166.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 Bacterial PH domain JmjN PF02375.12 KUM64166.1 - 0.12 11.8 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 jmjN domain Rotamase_3 PF13616.1 KUM64167.1 - 1.3e-18 67.3 0.3 2.4e-18 66.4 0.1 1.5 1 1 1 2 2 2 1 PPIC-type PPIASE domain Rotamase PF00639.16 KUM64167.1 - 1.9e-16 60.5 0.0 3.2e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 KUM64167.1 - 3.2e-05 24.5 1.9 7.7e-05 23.3 0.0 1.9 1 1 1 2 2 2 1 PPIC-type PPIASE domain UAA PF08449.6 KUM64168.1 - 6.5e-74 248.5 8.5 1.1e-73 247.8 5.9 1.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KUM64168.1 - 6.4e-07 29.4 26.9 0.00022 21.2 4.4 3.4 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 KUM64168.1 - 3.2e-05 23.1 1.2 0.13 11.3 0.0 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 KUM64168.1 - 0.00032 20.8 15.3 0.0056 16.8 1.2 3.0 3 0 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 KUM64168.1 - 0.0053 16.4 7.5 0.0053 16.4 5.2 2.6 2 1 0 2 2 2 2 Triose-phosphate Transporter family PXA PF02194.10 KUM64171.1 - 4.9e-41 140.3 0.0 6.9e-41 139.8 0.0 1.2 1 0 0 1 1 1 1 PXA domain IU_nuc_hydro PF01156.14 KUM64172.1 - 3.4e-88 295.8 0.0 4e-88 295.6 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Pkinase PF00069.20 KUM64173.1 - 9.9e-06 24.8 0.0 1.1e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM64173.1 - 0.029 13.4 0.0 0.039 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Vac_ImportDeg PF09783.4 KUM64175.1 - 5.2e-22 78.1 0.5 1.8e-21 76.4 0.3 1.7 2 0 0 2 2 2 1 Vacuolar import and degradation protein MMR_HSR1 PF01926.18 KUM64177.1 - 1.8e-20 73.0 0.2 4.4e-20 71.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.16 KUM64177.1 - 4.4e-19 68.0 0.1 9.7e-19 66.9 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 KUM64177.1 - 5.9e-11 41.8 0.2 2.8e-10 39.7 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KUM64177.1 - 1.1e-05 25.3 0.1 0.046 13.5 0.0 2.4 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 KUM64177.1 - 9.2e-05 21.9 0.4 1.7 8.0 0.0 4.0 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 KUM64177.1 - 0.007 15.1 0.1 0.015 14.0 0.1 1.5 1 0 0 1 1 1 1 ArgK protein AIG1 PF04548.11 KUM64177.1 - 0.0094 15.0 0.1 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 KUM64177.1 - 0.017 15.6 0.0 0.057 13.9 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein Arf PF00025.16 KUM64177.1 - 0.021 14.0 0.2 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_10 PF12846.2 KUM64177.1 - 0.096 12.0 0.0 0.91 8.9 0.0 2.1 1 1 0 1 1 1 0 AAA-like domain DUF258 PF03193.11 KUM64177.1 - 0.1 11.8 0.3 0.22 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 vATP-synt_E PF01991.13 KUM64177.1 - 0.63 9.2 3.6 0.31 10.3 0.0 1.9 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit HTH_Tnp_Tc5 PF03221.11 KUM64178.1 - 3.6e-14 52.3 0.0 6.7e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 KUM64178.1 - 3.6e-05 23.0 0.1 7.7e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.1 KUM64178.1 - 0.0014 18.0 0.1 0.0057 16.1 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_IclR PF09339.5 KUM64178.1 - 0.011 15.2 0.0 2 8.1 0.0 2.8 2 0 0 2 2 2 0 IclR helix-turn-helix domain MarR PF01047.17 KUM64178.1 - 0.011 15.3 0.1 0.065 12.9 0.0 2.3 2 0 0 2 2 2 0 MarR family HTH_Tnp_4 PF13613.1 KUM64178.1 - 0.022 14.2 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_10 PF04967.7 KUM64178.1 - 0.07 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 HTH DNA binding domain HTH_Crp_2 PF13545.1 KUM64178.1 - 0.17 11.7 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain IBN_N PF03810.14 KUM64179.1 - 2e-15 56.4 0.1 1.9e-14 53.3 0.0 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KUM64179.1 - 0.00011 22.1 3.2 0.00068 19.5 0.1 3.0 2 1 0 2 2 2 1 Exportin 1-like protein Glyco_hydro_2_N PF02837.13 KUM64181.1 - 1.1e-29 103.1 0.4 4.1e-29 101.2 0.0 2.1 3 0 0 3 3 3 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KUM64181.1 - 6.8e-16 58.0 0.0 3.1e-15 55.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 KUM64181.1 - 8.8e-13 48.6 0.2 2.3e-12 47.3 0.2 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 KUM64181.1 - 0.0026 17.9 0.1 0.0064 16.7 0.1 1.7 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Peptidase_M74 PF03411.8 KUM64181.1 - 0.14 11.3 0.3 4.2 6.5 0.0 2.3 2 0 0 2 2 2 0 Penicillin-insensitive murein endopeptidase SnoaL_2 PF12680.2 KUM64182.1 - 7.1e-09 36.0 0.1 8.8e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain CN_hydrolase PF00795.17 KUM64183.1 - 5.1e-35 120.5 0.0 6.7e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Cellulase PF00150.13 KUM64184.1 - 2.7e-19 69.4 2.2 6.4e-19 68.2 1.5 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Amino_oxidase PF01593.19 KUM64186.1 - 3.5e-70 237.3 0.2 2e-69 234.8 0.1 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KUM64186.1 - 2.1e-08 34.0 0.3 6.4e-08 32.5 0.2 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KUM64186.1 - 4.7e-05 22.4 1.6 0.1 11.5 0.3 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KUM64186.1 - 5.5e-05 23.4 0.3 0.1 13.0 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KUM64186.1 - 0.00021 21.4 0.4 0.08 12.9 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM64186.1 - 0.00071 19.3 0.4 0.61 9.8 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KUM64186.1 - 0.0036 16.4 0.5 0.045 12.8 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KUM64186.1 - 0.0089 15.1 0.1 0.015 14.4 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KUM64186.1 - 0.055 13.3 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KUM64186.1 - 0.062 12.8 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 KUM64186.1 - 0.17 10.6 0.0 0.3 9.9 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 KUM64186.1 - 0.18 10.2 0.3 2.6 6.4 0.2 2.2 2 0 0 2 2 2 0 HI0933-like protein DUF2975 PF11188.3 KUM64187.1 - 4.2 7.1 7.2 1.6 8.4 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Zn_clus PF00172.13 KUM64188.1 - 0.019 14.8 14.7 0.033 14.0 10.2 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.2 KUM64189.1 - 7.3e-26 90.3 0.2 4.5e-18 65.3 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KUM64189.1 - 7e-22 76.9 1.1 6.2e-09 35.8 0.0 5.4 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 KUM64189.1 - 1.2e-20 72.2 1.7 6.7e-07 28.8 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 KUM64189.1 - 6.4e-17 61.5 0.7 7.9e-07 29.4 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM64189.1 - 1.1e-12 46.8 0.1 0.00093 19.2 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ribosomal_L7Ae PF01248.21 KUM64190.1 - 1.3e-27 95.1 0.7 1.5e-27 94.9 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.6 KUM64190.1 - 0.028 14.0 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Zn_clus PF00172.13 KUM64191.1 - 4.4e-11 42.5 11.2 8.3e-11 41.6 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KUM64192.1 - 1.9e-39 135.4 41.0 2.2e-39 135.2 28.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM64192.1 - 6.1e-11 41.5 20.2 1.2e-10 40.5 14.0 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 KUM64192.1 - 0.99 7.3 8.7 0.71 7.8 0.2 2.3 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family NMO PF03060.10 KUM64194.1 - 2e-42 145.5 3.9 1.7e-32 112.8 0.3 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 KUM64194.1 - 1.5e-08 33.8 0.5 3.7e-06 26.0 0.3 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KUM64194.1 - 1.8e-07 30.3 3.9 6.5e-07 28.5 2.9 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KUM64194.1 - 5.3e-06 25.5 0.4 1.4e-05 24.2 0.3 1.6 1 1 0 1 1 1 1 Conserved region in glutamate synthase COesterase PF00135.23 KUM64196.1 - 2.9e-90 303.5 0.0 4.7e-90 302.8 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KUM64196.1 - 2.2e-11 43.7 0.3 7.5e-11 42.0 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KUM64196.1 - 0.00011 21.5 0.2 0.00024 20.4 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KUM64196.1 - 0.00053 19.7 0.2 0.0011 18.7 0.2 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lectin_C PF00059.16 KUM64196.1 - 0.69 10.5 3.6 0.85 10.2 1.2 2.1 1 1 1 2 2 2 0 Lectin C-type domain Ribosomal_S19e PF01090.14 KUM64198.1 - 7.2e-53 177.7 0.1 1e-52 177.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S19e Abhydrolase_6 PF12697.2 KUM64199.1 - 3.5e-23 82.6 0.7 8e-23 81.5 0.5 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM64199.1 - 2.1e-14 53.5 0.0 6.7e-14 51.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM64199.1 - 4.5e-10 39.4 0.0 4.7e-09 36.1 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DSPc PF00782.15 KUM64199.1 - 2.7e-09 36.7 0.0 9.1e-09 34.9 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Thioesterase PF00975.15 KUM64199.1 - 8.2e-05 22.9 0.0 0.00017 21.8 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain DUF1749 PF08538.5 KUM64199.1 - 0.00017 20.6 0.0 0.051 12.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1749) Lipase_3 PF01764.20 KUM64199.1 - 0.00043 19.9 0.2 0.038 13.5 0.1 2.4 1 1 0 2 2 2 1 Lipase (class 3) PTPlike_phytase PF14566.1 KUM64199.1 - 0.00095 19.2 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Hydrolase_4 PF12146.3 KUM64199.1 - 0.0015 18.3 0.0 0.0097 15.7 0.0 2.1 2 0 0 2 2 2 1 Putative lysophospholipase Ser_hydrolase PF06821.8 KUM64199.1 - 0.0024 17.4 0.3 0.035 13.7 0.1 2.7 2 1 0 2 2 2 1 Serine hydrolase PGAP1 PF07819.8 KUM64199.1 - 0.0053 16.3 0.1 0.019 14.5 0.0 1.9 1 1 0 1 1 1 1 PGAP1-like protein Trp_oprn_chp PF09534.5 KUM64199.1 - 0.0071 15.9 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) FSH1 PF03959.8 KUM64199.1 - 0.012 15.0 0.0 0.62 9.4 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase (FSH1) DUF2305 PF10230.4 KUM64199.1 - 0.018 14.4 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) LCAT PF02450.10 KUM64199.1 - 0.046 12.6 0.0 0.09 11.7 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_4 PF08386.5 KUM64199.1 - 0.085 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Y_phosphatase PF00102.22 KUM64199.1 - 0.12 11.7 0.0 0.46 9.7 0.0 2.0 2 0 0 2 2 2 0 Protein-tyrosine phosphatase ILVD_EDD PF00920.16 KUM64201.1 - 3.4e-204 679.0 0.4 4e-204 678.8 0.3 1.0 1 0 0 1 1 1 1 Dehydratase family DUF1772 PF08592.6 KUM64202.1 - 6.2e-21 74.5 0.1 1.3e-19 70.3 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) Pex2_Pex12 PF04757.9 KUM64203.1 - 1e-40 139.6 0.2 1e-40 139.6 0.1 1.4 2 0 0 2 2 2 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 KUM64203.1 - 0.0015 18.4 5.6 0.0029 17.4 3.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KUM64203.1 - 0.68 9.6 3.3 0.35 10.6 0.4 1.9 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 KUM64203.1 - 2.3 8.3 10.3 0.99 9.4 4.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Aldedh PF00171.17 KUM64204.1 - 7.6e-160 532.2 0.1 8.6e-160 532.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KUM64204.1 - 0.00025 20.3 0.0 0.64 9.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Phosphoesterase PF04185.9 KUM64205.1 - 5.7e-34 117.9 11.0 1.4e-33 116.6 5.7 2.3 2 1 0 2 2 2 1 Phosphoesterase family Ureidogly_hydro PF04115.7 KUM64206.1 - 3.4e-52 176.1 0.0 3.9e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase BTB PF00651.26 KUM64207.1 - 2.8e-05 24.0 0.0 4.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF309 PF03745.9 KUM64207.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF309) Sec63 PF02889.11 KUM64208.1 - 7.6e-198 656.1 0.0 4e-108 361.3 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KUM64208.1 - 1.2e-54 184.3 1.0 2.1e-31 108.6 0.0 4.0 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 KUM64208.1 - 5.6e-14 52.3 0.0 1.7e-05 24.7 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KUM64208.1 - 1.8e-09 37.3 0.0 1.5e-08 34.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KUM64208.1 - 0.00028 21.0 3.1 0.028 14.5 0.1 3.6 3 2 0 3 3 3 1 AAA domain T2SE PF00437.15 KUM64208.1 - 0.00063 18.7 0.0 1.2 8.0 0.0 2.8 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_10 PF12846.2 KUM64208.1 - 0.00085 18.8 0.0 3.7 6.8 0.0 4.2 4 0 0 4 4 4 2 AAA-like domain PhoH PF02562.11 KUM64208.1 - 0.0017 17.6 0.0 0.26 10.4 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.1 KUM64208.1 - 0.0046 16.6 0.0 1.1 9.0 0.0 3.1 3 0 0 3 3 3 1 Part of AAA domain Helicase_C_2 PF13307.1 KUM64208.1 - 0.027 14.4 0.0 2.5 8.0 0.0 3.3 3 0 0 3 3 3 0 Helicase C-terminal domain FtsK_SpoIIIE PF01580.13 KUM64208.1 - 0.03 13.7 0.0 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family MutS_V PF00488.16 KUM64209.1 - 5.4e-84 281.2 0.0 8.5e-84 280.6 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KUM64209.1 - 2.4e-39 135.2 0.0 1.2e-38 132.9 0.0 2.1 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KUM64209.1 - 4.8e-20 71.6 0.0 1.3e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KUM64209.1 - 1.1e-06 28.7 0.0 3.4e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 MutS domain II CCDC92 PF14916.1 KUM64209.1 - 0.019 14.5 1.3 0.038 13.5 0.0 2.2 2 0 0 2 2 2 0 Coiled-coil domain of unknown function AAA_29 PF13555.1 KUM64209.1 - 0.025 14.1 0.0 0.056 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MutS_IV PF05190.13 KUM64209.1 - 0.057 13.6 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 MutS family domain IV AAA_23 PF13476.1 KUM64209.1 - 0.11 12.8 0.0 0.45 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Peptidase_S9 PF00326.16 KUM64211.1 - 7.3e-50 169.1 0.1 1.5e-49 168.1 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KUM64211.1 - 3.3e-08 33.3 0.0 7.2e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KUM64211.1 - 2.2e-06 27.7 0.5 6.4e-06 26.2 0.4 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KUM64211.1 - 0.0024 16.4 0.1 0.094 11.1 0.0 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) PD40 PF07676.7 KUM64211.1 - 0.048 13.3 1.9 5.4 6.8 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat MFS_1 PF07690.11 KUM64212.1 - 1.3e-25 89.8 61.5 5e-24 84.6 22.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_43 PF04616.9 KUM64213.1 - 1.6e-25 89.8 1.1 3.7e-16 59.0 0.3 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 RNase_P_p30 PF01876.11 KUM64214.1 - 5.6e-50 168.4 0.0 7.6e-50 168.0 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Pkinase PF00069.20 KUM64215.1 - 7e-58 195.7 0.0 8.1e-58 195.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM64215.1 - 1.7e-18 66.6 0.0 2.4e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KUM64215.1 - 1.6e-07 31.3 0.5 9.1e-05 22.2 0.1 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KUM64215.1 - 0.0086 15.6 0.0 0.017 14.7 0.0 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 KUM64215.1 - 0.017 14.2 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KUM64215.1 - 0.024 13.6 0.0 0.038 12.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Aconitase_B_N PF11791.3 KUM64215.1 - 0.078 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Aconitate B N-terminal domain Sugar_tr PF00083.19 KUM64216.1 - 1.2e-20 73.5 1.0 5e-20 71.5 0.7 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4175 PF13779.1 KUM64216.1 - 0.029 12.1 0.4 0.035 11.8 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) ABC_membrane PF00664.18 KUM64216.1 - 0.065 12.6 1.0 0.11 11.9 0.7 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region DUF1523 PF07509.6 KUM64216.1 - 0.098 11.8 0.0 0.18 11.0 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1523) O-antigen_lig PF13425.1 KUM64216.1 - 0.1 12.5 2.7 0.087 12.8 1.1 1.6 1 1 0 1 1 1 0 O-antigen ligase like membrane protein PWWP PF00855.12 KUM64217.1 - 1e-15 57.7 0.0 1e-15 57.7 0.0 2.7 2 1 0 2 2 2 1 PWWP domain DUF908 PF06012.7 KUM64217.1 - 0.19 10.9 0.1 0.19 10.9 0.1 3.8 4 2 0 4 4 4 0 Domain of Unknown Function (DUF908) SpoIIE PF07228.7 KUM64218.1 - 4.2e-11 42.9 0.3 1.9e-10 40.7 0.1 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KUM64218.1 - 1.2e-09 37.9 0.1 1.9e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 KUM64218.1 - 6.8e-07 28.9 0.0 0.026 13.9 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C SH3_1 PF00018.23 KUM64219.1 - 2.3e-34 116.5 7.2 3.5e-13 48.6 0.1 4.1 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.7 KUM64219.1 - 5.8e-34 115.5 0.4 1e-33 114.7 0.3 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.1 KUM64219.1 - 1.7e-31 107.5 6.7 1.9e-12 46.5 0.2 3.8 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 KUM64219.1 - 9.2e-22 76.3 0.2 3.6e-08 32.7 0.0 4.2 4 0 0 4 4 4 3 Variant SH3 domain SH3_3 PF08239.6 KUM64219.1 - 2.3e-05 24.5 4.9 0.048 13.8 0.4 3.4 3 0 0 3 3 3 2 Bacterial SH3 domain SAM_1 PF00536.25 KUM64219.1 - 0.093 12.9 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Fungal_trans PF04082.13 KUM64220.1 - 2.9e-14 52.5 0.0 5.6e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ComA PF02679.10 KUM64221.1 - 3e-73 245.8 0.0 3.4e-73 245.6 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) DUF2542 PF10808.3 KUM64221.1 - 0.098 12.9 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2542) PAP2_3 PF14378.1 KUM64222.1 - 6.9e-07 28.9 6.3 6.1e-05 22.6 0.0 3.0 3 1 0 3 3 3 2 PAP2 superfamily SNF2_N PF00176.18 KUM64223.1 - 1.6e-62 210.9 0.5 2.8e-62 210.2 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KUM64223.1 - 1.3e-12 47.4 0.0 3.3e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 KUM64223.1 - 1.1e-05 24.9 12.1 1.1e-05 24.9 8.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KUM64223.1 - 0.00018 21.4 10.9 0.00018 21.4 7.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KUM64223.1 - 0.00038 20.2 12.0 0.00038 20.2 8.3 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KUM64223.1 - 0.00069 19.2 10.6 0.00069 19.2 7.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS91 PF14319.1 KUM64223.1 - 0.0068 15.8 3.5 0.0068 15.8 2.4 2.5 2 0 0 2 2 2 1 Transposase zinc-binding domain Osmo_CC PF08946.5 KUM64223.1 - 0.1 12.6 3.8 0.88 9.6 0.4 2.8 2 0 0 2 2 2 0 Osmosensory transporter coiled coil zf-RING_UBOX PF13445.1 KUM64223.1 - 0.34 10.6 5.2 1.2 8.9 3.6 2.0 1 0 0 1 1 1 0 RING-type zinc-finger LRR_8 PF13855.1 KUM64224.1 - 1e-06 28.3 4.6 0.031 14.0 0.5 4.6 4 2 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 KUM64224.1 - 0.5 10.5 8.2 48 4.4 0.0 6.1 7 0 0 7 7 7 0 Leucine Rich repeat LRR_4 PF12799.2 KUM64224.1 - 7.7 6.2 10.9 14 5.4 0.9 5.0 6 2 1 7 7 6 0 Leucine Rich repeats (2 copies) Pirin PF02678.11 KUM64225.1 - 7.9e-33 112.5 0.1 1.5e-32 111.6 0.1 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 KUM64225.1 - 7.4e-23 80.6 0.0 3.1e-22 78.6 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 KUM64225.1 - 9.3e-06 25.0 0.6 0.00012 21.4 0.8 2.3 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.7 KUM64225.1 - 0.14 11.6 0.1 1.3 8.4 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF861) PRKCSH PF07915.8 KUM64226.1 - 1.3e-19 70.7 0.2 1.3e-19 70.7 0.2 2.9 3 1 0 3 3 3 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 KUM64226.1 - 0.00063 19.2 0.3 0.004 16.6 0.2 2.0 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein adh_short_C2 PF13561.1 KUM64227.1 - 4.7e-20 72.3 0.2 5.8e-20 72.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KUM64227.1 - 2.6e-10 40.4 1.0 3.5e-10 40.0 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM64227.1 - 2.2e-06 27.4 0.6 3.8e-06 26.6 0.2 1.5 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 KUM64227.1 - 0.0011 18.6 1.4 0.0028 17.3 1.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase VWA_2 PF13519.1 KUM64227.1 - 0.1 12.7 0.2 0.33 11.0 0.1 1.9 2 0 0 2 2 2 0 von Willebrand factor type A domain Rad33 PF08730.5 KUM64228.1 - 0.042 13.2 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 Rad33 Abhydrolase_6 PF12697.2 KUM64229.1 - 2.9e-22 79.7 0.1 3.4e-22 79.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM64229.1 - 5.5e-11 42.4 0.0 7.4e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KUM64229.1 - 2e-09 37.3 0.0 2.8e-09 36.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KUM64229.1 - 4.1e-07 30.4 0.0 4.6e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Ndr PF03096.9 KUM64229.1 - 0.061 11.8 0.0 3.5 6.0 0.0 2.1 2 0 0 2 2 2 0 Ndr family CorA PF01544.13 KUM64230.1 - 1e-06 28.0 1.2 3.3e-06 26.3 0.5 2.0 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein EamA PF00892.15 KUM64230.1 - 0.03 14.3 1.5 0.052 13.5 1.0 1.3 1 0 0 1 1 1 0 EamA-like transporter family Pkinase PF00069.20 KUM64232.1 - 1.1e-23 83.7 0.0 2.1e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.2 KUM64232.1 - 1.6e-19 70.0 0.3 1.8e-07 31.3 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KUM64232.1 - 1.6e-14 52.8 0.6 1.3e-06 27.9 0.0 5.7 6 0 0 6 6 6 2 Ankyrin repeat Pkinase_Tyr PF07714.12 KUM64232.1 - 1.8e-13 50.1 0.0 9.3e-13 47.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Ank_3 PF13606.1 KUM64232.1 - 2.4e-11 42.7 0.1 0.0033 17.4 0.0 5.7 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 KUM64232.1 - 3.1e-11 43.4 0.0 0.00011 22.5 0.0 4.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM64232.1 - 5e-11 42.4 1.1 7.3e-05 22.8 0.1 4.4 4 1 1 5 5 5 2 Ankyrin repeats (many copies) tRNA-synt_1 PF00133.17 KUM64234.1 - 6.8e-219 727.8 0.1 3.6e-218 725.4 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KUM64234.1 - 9.3e-32 109.9 1.8 3.1e-31 108.1 1.3 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KUM64234.1 - 3.8e-17 62.0 0.3 6.6e-08 31.6 0.0 4.9 5 1 0 5 5 5 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 KUM64234.1 - 4.1e-08 32.7 2.9 2.6e-05 23.5 0.0 2.7 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 KUM64234.1 - 0.0055 16.7 7.2 0.0055 16.7 5.0 2.7 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm RelA_SpoT PF04607.12 KUM64236.1 - 3.6e-11 43.0 0.0 7.2e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins Serglycin PF04360.7 KUM64236.1 - 8e-07 28.8 0.1 1.3e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Serglycin Ank_2 PF12796.2 KUM64237.1 - 1.6e-21 76.3 1.4 1.7e-09 37.8 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KUM64237.1 - 3.4e-20 70.7 4.4 1.9e-06 27.3 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 KUM64237.1 - 1.3e-18 67.0 2.1 8.6e-12 45.2 0.0 3.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM64237.1 - 5.6e-13 47.7 0.3 0.0013 18.7 0.1 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KUM64237.1 - 1.2e-11 44.4 3.9 3.6e-05 23.8 0.2 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) NUDIX PF00293.23 KUM64238.1 - 1.5e-05 24.6 0.0 2.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain SLAC1 PF03595.12 KUM64239.1 - 6e-82 274.9 34.7 6.8e-82 274.7 24.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel HA PF03457.9 KUM64239.1 - 0.021 14.9 0.2 0.039 14.0 0.1 1.3 1 0 0 1 1 1 0 Helicase associated domain HSCB_C PF07743.8 KUM64241.1 - 4.8e-19 68.5 1.3 5e-18 65.3 0.2 2.1 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 KUM64241.1 - 8.5e-11 41.4 0.0 1.7e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain DUF4433 PF14487.1 KUM64241.1 - 0.16 11.6 0.1 0.22 11.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4433) WD40 PF00400.27 KUM64242.1 - 3.5e-43 143.9 22.9 1.4e-08 34.2 0.1 7.9 7 1 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 KUM64242.1 - 7.4e-14 50.7 6.8 7.4e-14 50.7 4.7 1.8 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Nbas_N PF15492.1 KUM64242.1 - 0.064 12.3 0.0 0.24 10.4 0.0 1.9 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal CAP_GLY PF01302.20 KUM64243.1 - 3.4e-16 58.6 0.6 7.4e-16 57.6 0.4 1.6 1 0 0 1 1 1 1 CAP-Gly domain DUF3552 PF12072.3 KUM64243.1 - 0.0012 18.1 34.7 0.0079 15.4 3.8 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF3552) TMF_DNA_bd PF12329.3 KUM64243.1 - 0.0015 18.3 25.3 1.2 8.9 0.5 5.1 5 0 0 5 5 5 3 TATA element modulatory factor 1 DNA binding PilJ PF13675.1 KUM64243.1 - 0.042 14.1 19.6 0.17 12.1 2.0 3.8 2 2 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3584 PF12128.3 KUM64243.1 - 0.049 10.9 26.8 0.24 8.7 15.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) EzrA PF06160.7 KUM64243.1 - 0.062 11.4 26.2 0.064 11.4 7.3 3.1 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA Reo_sigmaC PF04582.7 KUM64243.1 - 0.18 10.9 6.6 2.2 7.3 0.7 2.8 1 1 3 4 4 4 0 Reovirus sigma C capsid protein Mod_r PF07200.8 KUM64243.1 - 0.27 11.1 22.3 0.23 11.3 2.9 3.4 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein IncA PF04156.9 KUM64243.1 - 0.52 9.8 39.1 0.055 13.0 9.9 3.3 1 1 2 3 3 3 0 IncA protein NPV_P10 PF05531.7 KUM64243.1 - 0.56 10.4 13.5 2 8.7 0.8 3.6 4 0 0 4 4 3 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.2 KUM64243.1 - 0.87 9.4 38.0 1.8 8.3 0.7 3.5 2 1 1 3 3 3 0 Tropomyosin like SlyX PF04102.7 KUM64243.1 - 0.91 9.9 31.9 0.17 12.2 4.4 4.2 3 1 0 3 3 3 0 SlyX Spc7 PF08317.6 KUM64243.1 - 1.3 7.5 27.1 0.46 9.0 3.4 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein TBPIP PF07106.8 KUM64243.1 - 1.6 8.2 23.4 0.4 10.2 2.9 3.3 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Occludin_ELL PF07303.8 KUM64243.1 - 1.8 9.3 14.2 2 9.1 1.6 3.4 3 0 0 3 3 3 0 Occludin homology domain AAA_13 PF13166.1 KUM64243.1 - 2.4 6.5 23.4 0.13 10.6 5.0 2.7 2 1 0 3 3 3 0 AAA domain Pox_A_type_inc PF04508.7 KUM64243.1 - 2.8 7.9 15.7 16 5.6 1.2 4.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat zf-CCHC_4 PF14392.1 KUM64243.1 - 3 7.6 4.6 13 5.5 0.2 2.4 2 0 0 2 2 2 0 Zinc knuckle TPR_MLP1_2 PF07926.7 KUM64243.1 - 3.4 7.4 31.7 6.7 6.4 8.6 4.0 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Prominin PF05478.6 KUM64243.1 - 3.6 4.9 4.4 2.5 5.5 1.9 1.5 1 1 0 1 1 1 0 Prominin Cortex-I_coil PF09304.5 KUM64243.1 - 3.8 7.5 30.8 1.2 9.2 7.0 3.9 2 1 0 3 3 3 0 Cortexillin I, coiled coil Cauli_AT PF03233.8 KUM64243.1 - 4.1 7.0 11.1 0.34 10.5 1.0 3.0 2 1 1 3 3 3 0 Aphid transmission protein ATG16 PF08614.6 KUM64243.1 - 5.2 6.8 34.0 13 5.5 5.5 3.9 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) Adaptin_binding PF10199.4 KUM64243.1 - 7.1 6.9 31.0 3.9 7.7 1.2 3.3 3 1 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 DUF745 PF05335.8 KUM64243.1 - 10 5.6 13.3 19 4.6 5.6 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF745) 3-HAO PF06052.7 KUM64244.1 - 6.3e-55 184.7 0.0 7.4e-55 184.5 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 KUM64244.1 - 0.00041 19.7 0.0 0.00071 19.0 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 KUM64244.1 - 0.00074 18.9 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 KUM64244.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain RTC PF01137.16 KUM64245.1 - 2.5e-30 104.9 0.1 3.5e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 KUM64245.1 - 5.3e-30 103.4 0.0 8.6e-30 102.7 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain AvrPto PF11592.3 KUM64245.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Central core of the bacterial effector protein AvrPto adh_short PF00106.20 KUM64247.1 - 1.9e-05 24.6 0.0 3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM64247.1 - 0.00058 19.5 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 KUM64247.1 - 0.018 15.1 0.0 0.028 14.5 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Peptidase_M22 PF00814.20 KUM64247.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.5 1 1 0 1 1 1 0 Glycoprotease family Pkinase PF00069.20 KUM64248.1 - 4.3e-36 124.4 0.0 1.2e-21 77.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KUM64248.1 - 6.2e-13 48.4 0.0 1.8e-06 27.2 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KUM64248.1 - 0.0087 15.0 0.0 2.7 6.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KUM64248.1 - 0.0092 15.7 0.0 0.017 14.8 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family UQ_con PF00179.21 KUM64249.1 - 7.9e-09 35.0 0.0 9.2e-09 34.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme MFS_1 PF07690.11 KUM64251.1 - 3.2e-39 134.6 76.7 1.8e-34 119.0 34.1 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM64251.1 - 0.00059 18.5 14.5 0.00059 18.5 10.0 3.9 2 2 1 3 3 3 1 Sugar (and other) transporter DUF2633 PF11119.3 KUM64251.1 - 0.18 11.5 1.4 0.62 9.8 1.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) Peptidase_M24 PF00557.19 KUM64252.1 - 8.4e-43 146.3 0.0 1.1e-42 145.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 KUM64252.1 - 0.0011 18.8 5.9 0.0025 17.6 4.1 1.7 1 0 0 1 1 1 1 MYND finger EGF_CA PF07645.10 KUM64252.1 - 8.6 6.4 8.8 2.1 8.4 1.9 2.6 1 1 1 2 2 2 0 Calcium-binding EGF domain F-box-like PF12937.2 KUM64253.1 - 0.00029 20.5 1.5 0.002 17.8 0.0 2.7 3 0 0 3 3 3 1 F-box-like PRANC PF09372.5 KUM64253.1 - 0.003 17.5 0.0 0.0056 16.6 0.0 1.4 1 0 0 1 1 1 1 PRANC domain F-box PF00646.28 KUM64253.1 - 0.0042 16.6 0.4 0.062 12.9 0.0 2.6 2 0 0 2 2 2 1 F-box domain MFS_1 PF07690.11 KUM64254.1 - 1.1e-38 132.8 45.0 6.5e-38 130.3 18.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily UQ_con PF00179.21 KUM64256.1 - 1.4e-05 24.5 0.0 4.3e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme 3Beta_HSD PF01073.14 KUM64257.1 - 8.5e-46 155.8 0.0 4.7e-41 140.3 0.0 2.0 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KUM64257.1 - 6.2e-22 78.1 0.1 3.9e-21 75.5 0.0 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KUM64257.1 - 5.4e-13 48.4 0.0 5.1e-12 45.2 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 KUM64257.1 - 6.8e-07 28.4 0.0 4.9e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KUM64257.1 - 0.00053 20.0 0.0 0.0081 16.1 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KUM64257.1 - 0.054 12.3 0.0 0.25 10.2 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein FSH1 PF03959.8 KUM64259.1 - 1.1e-31 109.9 0.0 1.4e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KUM64259.1 - 2.3e-05 24.4 0.4 4.1e-05 23.5 0.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM64259.1 - 0.00038 20.2 0.0 0.00058 19.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KUM64259.1 - 0.0022 17.4 0.0 0.26 10.7 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Aldedh PF00171.17 KUM64260.1 - 3.9e-146 487.0 0.0 4.3e-146 486.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GMC_oxred_N PF00732.14 KUM64261.1 - 4.3e-60 203.3 0.2 5.7e-60 202.9 0.2 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KUM64261.1 - 2.9e-36 124.9 0.0 5.2e-36 124.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KUM64261.1 - 2.6e-05 24.1 0.1 9.7e-05 22.3 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KUM64261.1 - 4.6e-05 22.4 0.1 0.00016 20.7 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KUM64261.1 - 0.00058 19.0 0.2 0.0014 17.8 0.1 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KUM64261.1 - 0.00091 17.7 0.1 0.0016 16.9 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 KUM64261.1 - 0.0015 17.5 0.1 0.0024 16.8 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 KUM64261.1 - 0.0021 18.4 0.1 0.0061 16.9 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KUM64261.1 - 0.0039 17.0 0.1 0.03 14.2 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KUM64261.1 - 0.011 14.6 0.3 0.027 13.3 0.2 1.6 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.1 KUM64261.1 - 0.051 13.3 0.1 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding RNase_T PF00929.19 KUM64262.1 - 6.5e-23 81.8 0.0 9.7e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Glutaredoxin PF00462.19 KUM64263.1 - 2.8e-18 65.6 0.0 1.8e-17 63.0 0.0 2.2 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 KUM64263.1 - 8.2e-13 47.9 0.0 1.7e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KUM64263.1 - 0.00091 19.3 0.0 0.0076 16.3 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like SnoaL_2 PF12680.2 KUM64266.1 - 0.0024 18.2 0.0 0.0032 17.8 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain MFS_1 PF07690.11 KUM64267.1 - 6.7e-43 146.7 35.0 6.7e-43 146.7 24.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM64267.1 - 8.8e-06 24.5 37.8 8e-05 21.3 26.3 2.9 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4112 PF13430.1 KUM64267.1 - 5.1 7.0 7.2 7 6.6 0.0 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4112) DLH PF01738.13 KUM64268.1 - 1.2e-28 99.9 0.0 1.3e-28 99.7 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KUM64268.1 - 0.00045 19.9 0.0 0.00063 19.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family ketoacyl-synt PF00109.21 KUM64269.1 - 1.5e-70 237.5 0.1 3.8e-70 236.2 0.0 1.8 2 0 0 2 2 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KUM64269.1 - 9.9e-32 109.2 0.0 3.5e-31 107.5 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 KUM64269.1 - 3.1e-29 102.3 0.0 5.6e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.7 KUM64269.1 - 3.7e-26 91.5 0.0 6.5e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 KUM64269.1 - 7.9e-23 80.4 9.6 2.2e-12 47.0 1.6 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 KUM64269.1 - 5e-11 42.9 0.0 1.9e-10 41.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 KUM64269.1 - 2e-07 30.7 0.0 4.9e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.1 KUM64269.1 - 3.7e-07 29.8 0.0 9.1e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM64269.1 - 6.2e-07 29.2 0.0 2.4e-06 27.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 KUM64269.1 - 3.5e-06 26.1 1.3 6.7e-06 25.2 0.0 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_11 PF08241.7 KUM64269.1 - 3.8e-05 24.0 0.0 0.00018 21.9 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain adh_short PF00106.20 KUM64269.1 - 8.3e-05 22.5 0.0 0.00032 20.6 0.0 2.1 2 0 0 2 2 1 1 short chain dehydrogenase KR PF08659.5 KUM64269.1 - 0.0003 20.4 0.5 0.0012 18.5 0.1 2.1 2 0 0 2 2 2 1 KR domain Abhydrolase_5 PF12695.2 KUM64269.1 - 0.006 16.3 0.1 0.26 11.0 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Methyltransf_18 PF12847.2 KUM64269.1 - 0.0069 16.9 0.0 0.034 14.7 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 KUM64269.1 - 0.048 12.5 0.0 0.15 10.9 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KUM64269.1 - 0.086 11.5 0.0 0.18 10.4 0.0 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family FAD_binding_3 PF01494.14 KUM64270.1 - 3.1e-19 69.2 2.6 6.9e-18 64.8 1.8 2.3 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KUM64270.1 - 0.00012 22.0 1.6 0.00075 19.4 0.7 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KUM64270.1 - 0.0015 17.5 1.0 0.0026 16.7 0.7 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KUM64270.1 - 0.0044 16.6 1.6 0.0074 15.9 1.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 KUM64270.1 - 0.0068 16.1 0.1 0.023 14.4 0.0 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 KUM64270.1 - 0.019 15.3 1.9 0.019 15.3 1.3 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KUM64270.1 - 0.068 12.0 0.3 5.6 5.7 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_2 PF03446.10 KUM64270.1 - 0.11 12.3 0.2 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase SIS PF01380.17 KUM64271.1 - 2.7e-06 27.0 0.0 4.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 SIS domain DUF1492 PF07374.6 KUM64271.1 - 0.016 15.3 0.4 0.025 14.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) DUF16 PF01519.11 KUM64271.1 - 0.12 12.5 0.4 0.2 11.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 p450 PF00067.17 KUM64272.1 - 5e-46 157.1 0.0 2.7e-45 154.7 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 DIOX_N PF14226.1 KUM64273.1 - 1.2e-30 106.4 0.0 1.6e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KUM64273.1 - 5.9e-19 68.1 0.0 1.1e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 KUM64274.1 - 7.4e-15 54.5 7.3 1.1e-14 53.9 5.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 KUM64275.1 - 5.6e-21 74.9 6.4 6.3e-11 41.9 0.0 3.0 1 1 1 2 2 2 2 FAD binding domain DAO PF01266.19 KUM64275.1 - 4.4e-09 35.7 3.2 1.3e-05 24.2 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KUM64275.1 - 5.7e-09 35.8 1.6 1.4e-08 34.6 1.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KUM64275.1 - 3.2e-07 29.5 3.2 3.6e-07 29.3 1.5 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KUM64275.1 - 1.5e-05 24.9 0.1 4.4e-05 23.4 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KUM64275.1 - 1.7e-05 23.4 0.3 1.7e-05 23.4 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 KUM64275.1 - 3.8e-05 22.9 0.5 5.6e-05 22.4 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KUM64275.1 - 6.9e-05 22.0 2.2 0.013 14.6 0.5 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase GIDA PF01134.17 KUM64275.1 - 0.00011 21.1 1.4 0.00016 20.6 0.9 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KUM64275.1 - 0.00035 19.6 1.5 0.057 12.3 0.2 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KUM64275.1 - 0.00042 20.4 0.3 0.0011 19.0 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KUM64275.1 - 0.00055 19.1 0.1 0.00091 18.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 KUM64275.1 - 0.00075 19.8 0.9 0.0021 18.4 0.6 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM64275.1 - 0.0018 18.0 1.0 0.069 12.9 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KUM64275.1 - 0.0026 16.4 1.6 0.0056 15.3 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase AlaDh_PNT_C PF01262.16 KUM64275.1 - 0.0097 15.4 0.4 0.018 14.5 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain SE PF08491.5 KUM64275.1 - 0.049 12.4 0.0 0.29 9.9 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase 3HCDH_N PF02737.13 KUM64275.1 - 0.063 12.9 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KUM64275.1 - 0.18 11.2 0.9 0.31 10.4 0.6 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.20 KUM64276.1 - 5e-17 62.3 0.4 9.9e-17 61.3 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KUM64276.1 - 1.7e-08 34.3 0.0 2.4e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KUM64276.1 - 1.2e-06 28.5 0.0 8.8e-06 25.6 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KUM64276.1 - 0.00046 19.6 0.0 0.00063 19.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KUM64276.1 - 0.0061 15.2 0.0 0.0081 14.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KUM64276.1 - 0.082 11.8 0.0 0.15 10.9 0.0 1.4 1 1 0 1 1 1 0 Male sterility protein TauD PF02668.11 KUM64277.1 - 6.8e-60 202.9 0.4 1.1e-59 202.2 0.3 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 KUM64277.1 - 0.0068 16.7 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.5 KUM64277.1 - 0.037 12.9 0.1 0.084 11.7 0.0 1.6 1 1 0 1 1 1 0 CsiD Nbl1_Borealin_N PF10444.4 KUM64280.1 - 5.8e-21 73.6 3.7 1.2e-20 72.5 2.6 1.6 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal RhoGAP PF00620.22 KUM64281.1 - 1e-34 119.3 0.3 1.9e-34 118.4 0.2 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 KUM64281.1 - 2e-25 88.6 42.2 1.4e-11 44.2 4.5 4.8 5 0 0 5 5 5 4 LIM domain DUF1272 PF06906.6 KUM64281.1 - 0.0034 17.1 0.1 0.0034 17.1 0.1 4.0 3 1 1 4 4 4 2 Protein of unknown function (DUF1272) T2SE PF00437.15 KUM64281.1 - 0.023 13.6 0.1 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Sybindin PF04099.7 KUM64282.1 - 8.1e-47 158.5 0.0 1.5e-46 157.6 0.0 1.4 1 1 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 KUM64282.1 - 4.7e-08 32.9 0.0 1.2e-07 31.6 0.0 1.6 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region VWA_2 PF13519.1 KUM64283.1 - 2.4e-10 40.8 0.0 3.1e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 KUM64283.1 - 0.00025 20.7 0.1 0.00036 20.1 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.15 KUM64283.1 - 0.002 17.5 0.5 0.0096 15.4 0.3 2.3 1 0 0 1 1 1 1 Ubiquitin interaction motif VWA PF00092.23 KUM64283.1 - 0.0034 17.1 0.4 0.0056 16.4 0.2 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain DegV PF02645.11 KUM64283.1 - 0.051 12.6 0.1 0.079 12.0 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein, DegV family COG1307 MMtag PF10159.4 KUM64286.1 - 0.046 13.7 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 Kinase phosphorylation protein Ank_2 PF12796.2 KUM64287.1 - 4.3e-07 30.1 0.2 0.0021 18.3 0.0 2.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KUM64287.1 - 2.6e-05 24.5 0.1 0.0011 19.4 0.0 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Fungal_trans PF04082.13 KUM64290.1 - 3e-26 91.8 0.0 4.7e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM64290.1 - 4.9e-09 35.9 9.6 1.4e-08 34.5 6.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 KUM64291.1 - 3.7e-59 199.9 0.0 4.9e-39 134.0 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KUM64291.1 - 3.8e-26 91.7 0.0 2.5e-19 69.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 KUM64291.1 - 6.6e-12 45.4 0.0 1.7e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 KUM64291.1 - 1.2e-07 31.0 2.4 3.1e-05 23.1 0.0 3.2 4 0 0 4 4 4 2 Kinase-like APH PF01636.18 KUM64291.1 - 2.8e-07 30.5 0.0 0.0056 16.4 0.1 2.6 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KUM64291.1 - 0.0079 15.2 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KUM64291.1 - 0.091 11.5 0.1 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF4546 PF15079.1 KUM64291.1 - 0.17 11.0 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4546) MS_channel PF00924.13 KUM64292.1 - 2e-25 89.3 2.3 3.8e-25 88.4 1.6 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 KUM64292.1 - 0.00034 19.7 0.3 0.00084 18.4 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 KUM64292.1 - 0.0013 18.0 0.0 0.0032 16.7 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KUM64292.1 - 0.0016 18.5 0.1 0.0042 17.1 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KUM64292.1 - 0.0028 17.3 0.0 0.0089 15.8 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain DUF2648 PF10855.3 KUM64292.1 - 0.039 13.3 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) Tubulin PF00091.20 KUM64293.1 - 4.1e-67 226.1 0.0 5.6e-67 225.7 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KUM64293.1 - 2.4e-42 143.9 0.0 3.8e-42 143.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KUM64293.1 - 0.0014 18.1 0.0 0.0034 16.8 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Mito_carr PF00153.22 KUM64294.1 - 7.6e-67 221.0 2.4 4.2e-23 80.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.11 KUM64294.1 - 0.0092 15.8 0.0 4.4 7.2 0.0 2.4 2 0 0 2 2 2 2 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase SEEEED PF14797.1 KUM64295.1 - 0.014 15.4 5.9 0.023 14.8 4.1 1.3 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex BUD22 PF09073.5 KUM64295.1 - 1 8.3 7.7 1.3 8.0 5.3 1.1 1 0 0 1 1 1 0 BUD22 Sugar_tr PF00083.19 KUM64296.1 - 1.6e-105 353.2 25.0 1.9e-105 353.1 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM64296.1 - 8.7e-24 83.8 26.7 1.2e-21 76.7 12.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KUM64296.1 - 1e-07 30.7 29.9 4e-07 28.7 3.5 3.3 2 1 1 3 3 3 3 MFS/sugar transport protein Glyco_hydro_17 PF00332.13 KUM64297.1 - 0.00028 20.0 1.3 0.00062 18.8 0.9 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 DUF605 PF04652.11 KUM64297.1 - 1.6 8.0 14.1 2.5 7.4 9.8 1.2 1 0 0 1 1 1 0 Vta1 like HpaP PF09483.5 KUM64298.1 - 0.65 9.9 11.1 0.85 9.5 7.7 1.2 1 0 0 1 1 1 0 Type III secretion protein (HpaP) TMEM51 PF15345.1 KUM64298.1 - 6.3 6.4 9.0 0.55 9.8 1.9 1.9 2 0 0 2 2 2 0 Transmembrane protein 51 CDK5_activator PF03261.10 KUM64298.1 - 9.1 5.5 7.6 12 5.0 5.3 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF3653 PF12375.3 KUM64299.1 - 0.0043 17.2 0.2 0.0094 16.1 0.1 1.6 1 0 0 1 1 1 1 Phage protein Beta-lactamase PF00144.19 KUM64300.1 - 6e-41 140.5 0.0 8.1e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DAP_C PF07932.7 KUM64300.1 - 1.9e-40 136.9 0.1 4.4e-40 135.7 0.0 1.7 1 0 0 1 1 1 1 D-aminopeptidase, domain C DAP_B PF07930.7 KUM64300.1 - 1.9e-06 27.5 0.0 4.4e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 D-aminopeptidase, domain B UBN2_3 PF14244.1 KUM64302.1 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.4 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type MFS_1 PF07690.11 KUM64303.1 - 6.1e-29 100.8 37.7 4.9e-25 87.9 9.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SecE PF00584.15 KUM64303.1 - 0.011 15.3 1.2 3.4 7.3 0.0 3.2 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex Phage_holin_5 PF06946.6 KUM64303.1 - 0.51 10.5 4.3 1.6 8.9 0.2 2.7 2 0 0 2 2 2 0 Phage holin DAO PF01266.19 KUM64304.1 - 6.6e-56 189.7 0.1 8e-56 189.4 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KUM64304.1 - 0.00013 22.1 0.0 0.013 15.5 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM64304.1 - 0.00071 19.5 1.6 0.0016 18.4 0.7 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain ATG22 PF11700.3 KUM64306.1 - 1.2e-131 439.4 31.3 1.4e-131 439.2 21.7 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KUM64306.1 - 3e-08 32.7 37.3 5.8e-05 21.9 6.9 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily 2-oxoacid_dh PF00198.18 KUM64307.1 - 8.8e-78 260.7 0.3 1.4e-77 260.0 0.2 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KUM64307.1 - 5.7e-18 64.3 1.5 1.2e-17 63.2 1.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 KUM64307.1 - 5.9e-05 22.6 0.9 0.00015 21.3 0.6 1.7 1 0 0 1 1 1 1 Biotin-lipoyl like HlyD_2 PF12700.2 KUM64307.1 - 0.00055 19.1 7.6 0.0017 17.6 4.6 2.0 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 KUM64307.1 - 0.0019 18.5 1.0 0.031 14.6 0.3 2.4 1 1 1 2 2 2 1 HlyD family secretion protein Presenilin PF01080.12 KUM64307.1 - 0.41 9.4 3.5 0.61 8.8 2.4 1.2 1 0 0 1 1 1 0 Presenilin Ribonuc_L-PSP PF01042.16 KUM64308.1 - 7.9e-32 109.5 0.4 1e-31 109.2 0.2 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Aldedh PF00171.17 KUM64309.1 - 3.1e-103 345.5 0.0 3.7e-103 345.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pro_dh PF01619.13 KUM64310.1 - 4e-37 127.8 0.1 5e-37 127.5 0.1 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Fungal_trans PF04082.13 KUM64311.1 - 2.4e-14 52.8 0.1 4.1e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM64311.1 - 3.1e-07 30.1 11.9 5.8e-07 29.3 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATG2_CAD PF13329.1 KUM64311.1 - 0.073 12.6 0.7 0.14 11.7 0.5 1.3 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif Rota_NS6 PF04866.7 KUM64311.1 - 0.085 12.8 2.1 0.1 12.6 0.0 2.1 3 0 0 3 3 3 0 Rotavirus non-structural protein 6 C-C_Bond_Lyase PF15617.1 KUM64312.1 - 0.11 11.2 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 C-C_Bond_Lyase of the TIM-Barrel fold Clathrin PF00637.15 KUM64314.1 - 3.4e-24 85.0 1.1 3.4e-21 75.3 1.0 2.5 2 0 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.3 KUM64314.1 - 1.4e-18 66.4 0.0 3.1e-18 65.3 0.0 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal TPR_14 PF13428.1 KUM64314.1 - 0.00012 22.4 0.1 0.11 13.2 0.0 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-RING_5 PF14634.1 KUM64314.1 - 0.00062 19.4 5.5 0.0012 18.4 3.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KUM64314.1 - 0.0021 18.0 4.8 0.004 17.1 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KUM64314.1 - 0.006 16.3 6.6 0.011 15.4 4.6 1.5 1 0 0 1 1 1 1 Ring finger domain TPR_11 PF13414.1 KUM64314.1 - 0.0063 16.1 0.9 0.02 14.5 0.1 2.2 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 KUM64314.1 - 0.011 15.5 5.8 0.019 14.8 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2334 PF10096.4 KUM64314.1 - 0.013 14.9 0.2 0.03 13.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) zf-rbx1 PF12678.2 KUM64314.1 - 0.018 15.1 2.6 0.035 14.2 1.8 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 KUM64314.1 - 0.035 13.7 4.6 0.066 12.8 3.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Katanin_con80 PF13925.1 KUM64314.1 - 0.035 13.8 0.0 18 4.9 0.0 3.3 3 0 0 3 3 3 0 con80 domain of Katanin TPR_16 PF13432.1 KUM64314.1 - 0.047 14.3 0.3 0.39 11.4 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.1 KUM64314.1 - 0.071 12.7 4.5 0.14 11.8 3.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KUM64314.1 - 0.13 12.0 1.5 0.3 10.8 1.0 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 KUM64314.1 - 0.44 10.4 1.5 1 9.2 1.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_8 PF13181.1 KUM64314.1 - 0.56 10.1 3.6 0.49 10.2 0.2 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KUM64314.1 - 1.9 8.5 6.7 0.17 11.8 0.2 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat Nha1_C PF08619.5 KUM64315.1 - 2.5e-96 323.6 47.9 2.5e-96 323.6 33.2 2.5 1 1 1 2 2 2 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 KUM64315.1 - 1.3e-65 221.4 15.0 1.6e-65 221.0 10.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Serglycin PF04360.7 KUM64315.1 - 0.0081 15.9 4.7 0.018 14.7 3.2 1.5 1 0 0 1 1 1 1 Serglycin DUF3379 PF11859.3 KUM64315.1 - 0.43 9.7 2.0 0.73 8.9 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) RAP1 PF07218.6 KUM64315.1 - 2.9 5.8 7.0 5.9 4.8 4.8 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PX PF00787.19 KUM64316.1 - 8.2e-17 61.0 0.2 2e-16 59.8 0.1 1.6 1 0 0 1 1 1 1 PX domain Prefoldin_3 PF13758.1 KUM64316.1 - 0.011 15.4 3.1 0.018 14.8 0.2 2.5 2 0 0 2 2 2 0 Prefoldin subunit Tmemb_cc2 PF10267.4 KUM64316.1 - 0.059 11.9 0.4 0.1 11.1 0.3 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Arv1 PF04161.8 KUM64317.1 - 1.8e-41 142.3 0.0 5.7e-36 124.3 0.0 2.2 2 0 0 2 2 2 2 Arv1-like family LRR_4 PF12799.2 KUM64319.1 - 1.9e-25 87.9 40.5 4.8e-06 26.0 0.8 9.2 3 2 9 12 12 12 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KUM64319.1 - 9.2e-24 82.9 38.2 2.7e-06 27.0 0.4 7.9 5 2 2 8 8 8 5 Leucine rich repeat LRR_1 PF00560.28 KUM64319.1 - 1.2e-09 36.8 34.0 0.64 10.2 0.0 12.3 10 3 1 11 11 11 4 Leucine Rich Repeat LRR_6 PF13516.1 KUM64319.1 - 2.4e-09 36.3 27.9 0.2 11.8 0.0 10.6 7 3 2 9 9 9 5 Leucine Rich repeat LRR_7 PF13504.1 KUM64319.1 - 5.2e-08 31.8 35.6 1.2 9.6 0.3 12.1 13 0 0 13 13 13 4 Leucine rich repeat LRR_9 PF14580.1 KUM64319.1 - 3.6e-06 26.6 11.9 0.0034 16.9 1.8 4.0 1 1 2 4 4 4 3 Leucine-rich repeat Cupin_1 PF00190.17 KUM64320.1 - 4.9e-16 58.4 0.0 7.4e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 KUM64320.1 - 1.6e-10 40.3 0.2 3.2e-10 39.3 0.1 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 KUM64320.1 - 0.0016 17.8 0.0 0.0043 16.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Dynamin_N PF00350.18 KUM64321.1 - 2.3e-31 108.8 0.7 5.4e-31 107.6 0.0 1.9 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 KUM64321.1 - 1.6e-20 73.1 0.0 1.8e-19 69.6 0.0 2.3 2 0 0 2 2 2 1 Dynamin central region GED PF02212.13 KUM64321.1 - 7.4e-05 22.5 0.3 0.00031 20.5 0.0 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KUM64321.1 - 8.5e-05 22.4 0.0 0.00034 20.5 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KUM64321.1 - 0.00079 18.7 0.1 0.026 13.7 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 KUM64321.1 - 0.011 16.2 0.0 0.11 12.9 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein Syndecan PF01034.15 KUM64322.1 - 0.0069 16.0 0.0 0.02 14.5 0.0 1.7 2 0 0 2 2 2 1 Syndecan domain DUF347 PF03988.7 KUM64322.1 - 0.028 14.3 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) TMEM154 PF15102.1 KUM64322.1 - 0.1 12.2 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.1 KUM64322.1 - 0.12 12.8 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Flavin_Reduct PF01613.13 KUM64323.1 - 6.4e-16 58.5 0.0 9.2e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Pyridox_oxidase PF01243.15 KUM64323.1 - 0.014 15.3 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase GlutR_dimer PF00745.15 KUM64324.1 - 0.062 13.2 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain AAA PF00004.24 KUM64325.1 - 1.4e-07 31.7 0.2 8.6e-07 29.2 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KUM64325.1 - 2.4e-05 24.3 0.1 0.0001 22.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KUM64325.1 - 0.0005 20.2 0.0 0.0016 18.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KUM64325.1 - 0.00068 20.4 0.0 0.0029 18.4 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KUM64325.1 - 0.003 17.2 0.0 0.0085 15.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 KUM64325.1 - 0.0082 15.0 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 KUM64325.1 - 0.02 14.4 0.0 0.055 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 KUM64325.1 - 0.022 13.4 0.0 0.036 12.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_18 PF13238.1 KUM64325.1 - 0.026 14.8 0.0 0.074 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KUM64325.1 - 0.03 13.2 0.0 0.066 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.10 KUM64325.1 - 0.097 11.3 0.2 0.49 9.0 0.0 2.2 3 0 0 3 3 3 0 Rad17 cell cycle checkpoint protein Herpes_Helicase PF02689.9 KUM64325.1 - 0.41 8.3 0.0 0.6 7.7 0.0 1.1 1 0 0 1 1 1 0 Helicase SBP56 PF05694.6 KUM64326.1 - 3.2e-06 25.9 0.0 0.00032 19.3 0.0 2.9 2 1 0 2 2 2 2 56kDa selenium binding protein (SBP56) SGL PF08450.7 KUM64326.1 - 0.0076 15.6 0.0 4.1 6.6 0.0 3.1 3 0 0 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region Lactonase PF10282.4 KUM64326.1 - 0.0092 15.0 0.3 5.5 5.9 0.1 2.8 2 1 1 3 3 3 2 Lactonase, 7-bladed beta-propeller Cupin_2 PF07883.6 KUM64327.1 - 5.8e-11 41.7 0.1 8.1e-11 41.2 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 KUM64327.1 - 2.2e-09 36.8 0.0 3e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_4 PF08007.7 KUM64327.1 - 0.0023 17.2 0.0 0.0034 16.6 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_6 PF12852.2 KUM64327.1 - 0.029 13.9 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Cupin 3-HAO PF06052.7 KUM64327.1 - 0.06 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase Fungal_trans PF04082.13 KUM64328.1 - 7.2e-24 84.0 1.5 1.3e-23 83.1 1.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KUM64328.1 - 6.2e-10 38.8 12.7 0.00015 21.8 2.7 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KUM64328.1 - 1.2e-06 28.4 5.9 1.2e-06 28.4 4.1 3.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KUM64328.1 - 0.00027 21.0 17.3 0.023 15.0 2.4 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KUM64328.1 - 0.15 12.2 3.2 0.19 11.9 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KUM64328.1 - 3 7.8 6.7 2.6 8.0 0.7 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger ATP_synt_H PF05493.8 KUM64330.1 - 0.0031 17.5 0.3 0.007 16.4 0.0 1.7 2 0 0 2 2 2 1 ATP synthase subunit H OppC_N PF12911.2 KUM64330.1 - 0.044 13.1 0.1 0.076 12.3 0.0 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C BAR_2 PF10455.4 KUM64331.1 - 3.1e-62 210.1 3.0 4.4e-62 209.6 2.1 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 KUM64331.1 - 3e-19 69.4 7.0 4e-18 65.7 4.9 2.0 1 1 0 1 1 1 1 BAR domain ATP-synt_B PF00430.13 KUM64331.1 - 0.017 14.8 1.1 0.017 14.8 0.8 3.0 3 0 0 3 3 3 0 ATP synthase B/B' CF(0) DUF1795 PF08786.6 KUM64331.1 - 0.065 13.0 0.1 0.065 13.0 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1795) SPATA19 PF15212.1 KUM64331.1 - 0.092 12.7 0.0 0.26 11.3 0.0 1.7 2 0 0 2 2 2 0 Spermatogenesis-associated protein 19, mitochondrial DUF2580 PF10824.3 KUM64331.1 - 0.71 10.2 6.7 0.49 10.7 1.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2580) Optomotor-blind PF11078.3 KUM64332.1 - 0.012 15.9 0.5 0.032 14.5 0.0 1.9 2 0 0 2 2 2 0 Optomotor-blind protein N-terminal region Fungal_trans_2 PF11951.3 KUM64333.1 - 1.9e-19 69.5 0.1 1.3e-14 53.6 0.3 3.0 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM64333.1 - 2.6e-07 30.4 10.1 4.9e-07 29.5 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KUM64333.1 - 0.042 12.7 0.0 0.076 11.8 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Methyltransf_8 PF05148.10 KUM64334.1 - 2.2e-54 184.4 0.0 7.6e-52 176.1 0.0 2.7 3 0 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.7 KUM64334.1 - 3.7e-06 27.3 0.1 3.5e-05 24.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Mucin PF01456.12 KUM64334.1 - 1.7 8.4 10.1 3 7.6 7.0 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Spc97_Spc98 PF04130.8 KUM64335.1 - 3.7e-134 448.0 1.0 4.7e-134 447.6 0.7 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Methyltransf_23 PF13489.1 KUM64337.1 - 4.6e-14 52.4 0.0 7.2e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM64337.1 - 1.9e-10 41.0 0.0 4.7e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM64337.1 - 6.5e-08 32.9 0.0 2.3e-07 31.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM64337.1 - 6.7e-07 29.0 0.0 0.0083 15.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 KUM64337.1 - 8.7e-06 26.2 0.0 0.00017 22.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KUM64337.1 - 1.3e-05 24.3 0.0 8.9e-05 21.6 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 KUM64337.1 - 2.4e-05 24.6 0.0 0.00015 22.0 0.0 2.3 2 1 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KUM64337.1 - 0.00016 20.9 0.0 0.0018 17.4 0.0 2.5 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.11 KUM64337.1 - 0.0007 18.0 0.0 0.0052 15.1 0.0 2.0 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_26 PF13659.1 KUM64337.1 - 0.01 15.8 0.2 0.051 13.6 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain TPMT PF05724.6 KUM64337.1 - 0.029 13.7 0.0 0.33 10.3 0.0 2.1 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) KH_1 PF00013.24 KUM64338.1 - 0.00014 21.3 0.0 0.0004 19.9 0.0 1.8 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 KUM64338.1 - 0.0023 17.5 0.1 0.016 14.8 0.0 2.3 2 0 0 2 2 2 1 KH domain GAGA_bind PF06217.7 KUM64338.1 - 0.29 11.0 17.6 0.45 10.4 12.2 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Band_3_cyto PF07565.8 KUM64338.1 - 4.5 6.6 13.9 7.2 6.0 9.6 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain NPR3 PF03666.8 KUM64338.1 - 9.4 4.6 15.7 13 4.1 10.9 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Proteasome PF00227.21 KUM64339.1 - 6.4e-58 195.1 0.1 8e-58 194.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KUM64339.1 - 1.1e-13 50.1 0.0 2.3e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Glucosamine_iso PF01182.15 KUM64341.1 - 2.1e-59 200.6 0.0 2.5e-59 200.3 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DAO PF01266.19 KUM64342.1 - 1.5e-46 158.9 0.1 2.4e-46 158.3 0.1 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KUM64342.1 - 1.7e-06 27.8 0.0 0.0055 16.4 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.17 KUM64342.1 - 3.1e-05 23.0 0.0 0.00014 20.8 0.0 2.0 2 1 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KUM64342.1 - 8.4e-05 22.7 0.0 0.0032 17.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KUM64342.1 - 0.00015 20.8 0.1 0.25 10.2 0.0 2.3 2 1 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KUM64342.1 - 0.00038 20.3 0.0 0.58 9.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM64342.1 - 0.0012 18.8 0.0 0.0035 17.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 KUM64342.1 - 0.028 14.5 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 KUM64342.1 - 0.08 12.7 0.0 0.23 11.2 0.0 1.7 2 0 0 2 2 2 0 ThiF family Trp_halogenase PF04820.9 KUM64342.1 - 0.091 11.3 0.0 6.1 5.3 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Afi1 PF07792.7 KUM64344.1 - 1.1e-63 213.5 0.0 1.8e-63 212.8 0.0 1.3 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 KUM64344.1 - 1.2e-38 131.2 0.0 2e-38 130.5 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 KUM64344.1 - 5.9e-10 38.1 0.0 0.0032 16.0 0.0 4.2 3 2 2 5 5 5 3 Transport protein Avl9 DUF2347 PF09804.4 KUM64344.1 - 0.036 13.3 0.0 0.1 11.8 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Peripla_BP_6 PF13458.1 KUM64344.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein dUTPase PF00692.14 KUM64345.1 - 1.1e-43 147.7 0.0 1.4e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 dUTPase DCD PF06559.6 KUM64345.1 - 0.046 12.0 0.0 0.053 11.8 0.0 1.1 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) Phos_pyr_kin PF08543.7 KUM64346.1 - 5.7e-13 48.6 0.0 2.3e-12 46.6 0.0 1.8 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 KUM64346.1 - 1.4e-07 30.9 2.0 1.2e-06 27.9 0.1 2.8 2 1 0 2 2 2 1 pfkB family carbohydrate kinase p450 PF00067.17 KUM64347.1 - 2.3e-05 23.0 0.0 4.6e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome P450 RRM_1 PF00076.17 KUM64348.1 - 2.9e-12 46.0 0.0 7.4e-07 28.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM64348.1 - 2.2e-09 37.1 0.0 3e-07 30.3 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM64348.1 - 0.00012 21.8 0.0 0.00027 20.7 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_6 PF13405.1 KUM64349.1 - 2.6e-12 45.4 5.2 4.9e-06 25.9 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 KUM64349.1 - 8e-12 43.5 1.9 6.1e-06 25.1 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KUM64349.1 - 2.6e-10 40.2 1.2 2.3e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KUM64349.1 - 5.9e-07 28.9 0.8 0.0071 15.9 0.1 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KUM64349.1 - 9.5e-07 27.8 7.4 0.0048 16.1 0.5 2.5 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.1 KUM64349.1 - 0.011 15.5 0.0 0.45 10.4 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain RabGAP-TBC PF00566.13 KUM64350.1 - 3.1e-29 101.9 0.1 1.4e-24 86.7 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Ribosomal_L11_N PF03946.9 KUM64351.1 - 1.6e-17 62.7 0.0 2.3e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KUM64351.1 - 1.1e-09 38.3 0.2 1.6e-09 37.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Adeno_PX PF05829.7 KUM64351.1 - 0.071 12.6 1.6 0.39 10.2 0.1 2.3 2 0 0 2 2 2 0 Adenovirus late L2 mu core protein (Protein X) Glyco_transf_41 PF13844.1 KUM64352.1 - 4.5e-99 331.5 0.0 2.6e-50 170.7 0.0 3.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_11 PF13414.1 KUM64352.1 - 1.3e-19 69.6 11.8 3.2e-06 26.7 0.0 4.6 4 0 0 4 4 4 3 TPR repeat TPR_1 PF00515.23 KUM64352.1 - 4.8e-16 57.5 5.6 4.3e-05 22.9 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 KUM64352.1 - 3e-14 51.6 10.1 0.03 14.2 0.0 5.9 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_12 PF13424.1 KUM64352.1 - 9.8e-12 44.6 9.5 1.1e-06 28.4 0.2 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KUM64352.1 - 1.1e-10 40.8 2.7 0.46 10.8 0.0 5.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 KUM64352.1 - 1.1e-09 38.0 7.1 0.066 13.8 0.0 5.9 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 KUM64352.1 - 2.9e-09 36.0 1.4 0.0014 18.2 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KUM64352.1 - 6.5e-08 33.0 11.9 0.041 14.5 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KUM64352.1 - 1.3e-05 24.5 2.4 0.65 9.9 0.0 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KUM64352.1 - 2.4e-05 24.5 6.4 0.05 13.9 0.0 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 KUM64352.1 - 0.00042 20.1 14.4 0.16 11.9 0.0 6.2 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 KUM64352.1 - 0.004 17.5 1.1 14 6.3 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 KUM64352.1 - 0.0043 17.1 0.7 2.8 8.1 0.0 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KUM64352.1 - 0.011 15.5 5.9 0.077 12.8 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_5 PF12688.2 KUM64352.1 - 0.027 14.5 1.0 0.45 10.5 0.0 2.8 3 0 0 3 3 3 0 Tetratrico peptide repeat DUF905 PF06006.7 KUM64352.1 - 0.031 13.6 0.0 0.091 12.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF905) DUF2225 PF09986.4 KUM64352.1 - 0.41 10.0 0.0 1.9 7.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Sel1 PF08238.7 KUM64352.1 - 6.7 7.4 7.0 1.5 9.5 0.4 3.3 3 1 0 3 3 3 0 Sel1 repeat Myb_DNA-binding PF00249.26 KUM64353.1 - 8.2e-24 83.4 1.6 6.6e-13 48.4 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KUM64353.1 - 4.1e-18 65.2 6.6 1e-13 51.1 0.0 2.6 2 1 0 3 3 3 2 Myb-like DNA-binding domain DUF2774 PF11242.3 KUM64353.1 - 0.01 15.7 0.0 0.035 14.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) Myb_DNA-bind_4 PF13837.1 KUM64353.1 - 0.031 14.3 1.5 0.095 12.8 0.1 2.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain HTH_23 PF13384.1 KUM64353.1 - 0.051 13.2 0.1 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_38 PF13936.1 KUM64353.1 - 0.063 12.8 0.1 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain NST1 PF13945.1 KUM64354.1 - 0.034 14.2 3.8 0.033 14.2 2.6 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator BLVR PF06375.6 KUM64354.1 - 0.04 13.7 7.1 0.045 13.5 4.9 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) HSP90 PF00183.13 KUM64354.1 - 0.079 11.3 3.3 0.084 11.2 2.3 1.0 1 0 0 1 1 1 0 Hsp90 protein Med19 PF10278.4 KUM64354.1 - 0.15 11.7 7.2 0.15 11.7 5.0 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RR_TM4-6 PF06459.7 KUM64354.1 - 0.35 10.7 2.8 0.37 10.6 2.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Protocadherin PF08374.6 KUM64354.1 - 1.3 8.5 5.4 1.4 8.4 3.8 1.1 1 0 0 1 1 1 0 Protocadherin Peptidase_S49_N PF08496.5 KUM64354.1 - 2.1 8.1 5.0 2.4 7.9 3.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Glyco_hydro_31 PF01055.21 KUM64355.1 - 1.6e-127 425.9 3.4 2e-127 425.7 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KUM64355.1 - 6.6e-05 22.6 2.2 0.0022 17.8 0.0 3.2 3 0 0 3 3 3 1 Galactose mutarotase-like Ring_hydroxyl_A PF00848.14 KUM64356.1 - 0.038 13.6 0.6 0.077 12.6 0.4 1.4 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) DUF3405 PF11885.3 KUM64357.1 - 3.2e-25 88.3 0.0 3.6e-25 88.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) SKG6 PF08693.5 KUM64358.1 - 3.5e-07 29.4 0.1 3.5e-07 29.4 0.1 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Protocadherin PF08374.6 KUM64358.1 - 0.023 14.3 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Protocadherin Asp_decarbox PF02261.11 KUM64358.1 - 0.035 13.6 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 Aspartate decarboxylase Podoplanin PF05808.6 KUM64358.1 - 0.048 13.2 0.5 0.048 13.2 0.4 1.7 2 0 0 2 2 2 0 Podoplanin DUF2414 PF10309.4 KUM64359.1 - 4.3e-22 77.5 0.1 6.7e-22 76.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) LisH PF08513.6 KUM64360.1 - 0.00094 18.8 0.1 0.0021 17.7 0.1 1.6 1 0 0 1 1 1 1 LisH WD40 PF00400.27 KUM64360.1 - 0.0014 18.4 3.8 8.5 6.4 0.1 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat SET PF00856.23 KUM64361.1 - 6.3e-08 33.0 0.8 0.00039 20.7 0.1 3.2 4 0 0 4 4 4 2 SET domain TPR_11 PF13414.1 KUM64361.1 - 0.008 15.7 0.4 0.021 14.4 0.3 1.7 1 0 0 1 1 1 1 TPR repeat TPR_9 PF13371.1 KUM64361.1 - 0.011 15.5 0.4 0.029 14.1 0.3 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-MYND PF01753.13 KUM64361.1 - 0.16 11.9 3.3 0.38 10.6 2.3 1.7 1 0 0 1 1 1 0 MYND finger Sigma70_ner PF04546.8 KUM64361.1 - 1 8.9 4.7 1.8 8.1 3.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region WD40 PF00400.27 KUM64362.1 - 8.6e-26 88.8 14.6 2.9e-08 33.2 0.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat DPM2 PF07297.7 KUM64367.1 - 1.9e-33 114.5 1.4 2.3e-33 114.3 1.0 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 KUM64367.1 - 6.7e-05 22.5 0.6 8.4e-05 22.2 0.4 1.1 1 0 0 1 1 1 1 PIG-P DUF4083 PF13314.1 KUM64367.1 - 0.00041 20.1 1.5 0.00045 19.9 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4083) Cation_efflux PF01545.16 KUM64367.1 - 0.029 13.4 0.1 0.033 13.2 0.1 1.0 1 0 0 1 1 1 0 Cation efflux family DUF1469 PF07332.6 KUM64367.1 - 0.049 13.3 0.7 0.061 13.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) HAMP PF00672.20 KUM64367.1 - 0.39 10.9 1.9 6.9 6.9 0.4 2.1 2 0 0 2 2 2 0 HAMP domain DUF3169 PF11368.3 KUM64367.1 - 0.56 9.3 3.0 2.5 7.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) FixQ PF05545.6 KUM64367.1 - 0.63 9.7 4.5 20 4.9 2.3 2.3 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF2611 PF11022.3 KUM64367.1 - 0.82 9.8 2.8 0.51 10.4 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2611) MA3 PF02847.12 KUM64368.1 - 1.2e-26 92.6 0.1 3.6e-26 91.0 0.0 1.9 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.14 KUM64368.1 - 1.6e-24 86.4 0.6 2.8e-24 85.7 0.4 1.4 1 0 0 1 1 1 1 MIF4G domain APH PF01636.18 KUM64369.1 - 3.5e-39 134.9 0.0 6.3e-39 134.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KUM64369.1 - 1.9e-05 23.9 0.0 0.0001 21.5 0.0 1.9 1 1 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 KUM64369.1 - 0.0011 18.4 0.0 0.15 11.3 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.15 KUM64369.1 - 0.0027 17.2 0.0 0.0037 16.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 KUM64369.1 - 0.0041 15.8 0.0 0.051 12.1 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) Kdo PF06293.9 KUM64369.1 - 0.012 14.6 0.0 0.051 12.6 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family BRF1 PF07741.8 KUM64370.1 - 0.0096 16.1 10.2 0.011 15.9 7.1 1.1 1 0 0 1 1 1 1 Brf1-like TBP-binding domain GOLD_2 PF13897.1 KUM64370.1 - 0.033 14.4 0.4 0.035 14.3 0.3 1.0 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DUF2146 PF10220.4 KUM64370.1 - 0.037 12.0 1.4 0.043 11.8 1.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) SR-25 PF10500.4 KUM64370.1 - 0.13 11.7 18.1 0.14 11.6 12.6 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-DHHC PF01529.15 KUM64370.1 - 0.13 11.5 2.8 0.14 11.4 2.0 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase PcfK PF14058.1 KUM64370.1 - 0.14 12.3 11.9 0.15 12.1 8.3 1.1 1 0 0 1 1 1 0 PcfK-like protein DUF1284 PF06935.6 KUM64370.1 - 0.16 12.1 3.5 0.2 11.8 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1284) BLVR PF06375.6 KUM64370.1 - 0.16 11.7 12.6 0.19 11.5 8.7 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) YqfQ PF14181.1 KUM64370.1 - 0.23 11.4 9.5 0.26 11.3 6.6 1.0 1 0 0 1 1 1 0 YqfQ-like protein Eapp_C PF10238.4 KUM64370.1 - 0.28 11.0 5.7 0.29 11.0 3.9 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF2413 PF10310.4 KUM64370.1 - 0.29 9.8 5.8 0.28 9.9 4.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF1632 PF07857.7 KUM64370.1 - 0.3 10.3 2.4 0.34 10.1 1.6 1.0 1 0 0 1 1 1 0 CEO family (DUF1632) GAGA_bind PF06217.7 KUM64370.1 - 0.42 10.5 9.3 0.42 10.5 6.5 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2096 PF09869.4 KUM64370.1 - 0.42 10.4 4.1 0.5 10.2 2.9 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) AIF_C PF14721.1 KUM64370.1 - 0.47 10.7 2.7 0.46 10.7 1.8 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term EIIBC-GUT_N PF03612.9 KUM64370.1 - 0.47 10.0 3.1 0.49 9.9 2.1 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus TORC_M PF12885.2 KUM64370.1 - 0.48 10.1 2.1 0.5 10.1 1.5 1.1 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain Folate_carrier PF01770.13 KUM64370.1 - 0.56 8.6 3.6 0.56 8.6 2.5 1.0 1 0 0 1 1 1 0 Reduced folate carrier Tom37_C PF11801.3 KUM64370.1 - 0.63 9.8 5.5 0.72 9.7 3.8 1.1 1 0 0 1 1 1 0 Tom37 C-terminal domain DDHD PF02862.12 KUM64370.1 - 0.74 9.5 6.5 0.81 9.4 4.5 1.0 1 0 0 1 1 1 0 DDHD domain Cnd1_N PF12922.2 KUM64370.1 - 1 8.9 7.0 1.2 8.7 4.8 1.1 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term Glyco_transf_15 PF01793.11 KUM64370.1 - 1.1 8.1 4.8 1.2 8.0 3.3 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF1168 PF06658.7 KUM64370.1 - 1.3 8.5 20.0 1.5 8.3 13.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) IFT43 PF15305.1 KUM64370.1 - 1.4 8.9 6.6 1.5 8.8 4.6 1.1 1 0 0 1 1 1 0 Intraflagellar transport protein 43 HSP90 PF00183.13 KUM64370.1 - 2.1 6.6 9.6 2.3 6.5 6.7 1.0 1 0 0 1 1 1 0 Hsp90 protein RNA_pol_Rpc4 PF05132.9 KUM64370.1 - 2.3 8.1 8.2 2.6 8.0 5.7 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF3987 PF13148.1 KUM64370.1 - 2.4 6.6 7.3 2.5 6.5 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) ATP-synt_E PF05680.7 KUM64370.1 - 2.6 8.0 10.5 3.2 7.7 7.3 1.1 1 0 0 1 1 1 0 ATP synthase E chain CDC45 PF02724.9 KUM64370.1 - 2.7 5.8 6.7 2.9 5.7 4.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2058 PF09831.4 KUM64370.1 - 2.8 7.7 12.0 3.3 7.5 8.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF4557 PF15101.1 KUM64370.1 - 2.9 7.6 6.2 3.2 7.5 4.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) U79_P34 PF03064.11 KUM64370.1 - 3 7.2 12.2 3.5 7.0 8.4 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Peptidase_S49_N PF08496.5 KUM64370.1 - 3.1 7.5 12.3 3.6 7.3 8.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NPR3 PF03666.8 KUM64370.1 - 3.6 6.0 8.3 3.9 5.9 5.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Sec62 PF03839.11 KUM64370.1 - 4 6.7 9.7 4.5 6.6 6.8 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 OATP PF03137.15 KUM64370.1 - 4.1 5.3 4.9 4.3 5.2 3.4 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family NARP1 PF12569.3 KUM64370.1 - 5.7 5.5 13.2 6.2 5.4 9.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SHR3_chaperone PF08229.6 KUM64370.1 - 6.9 5.5 7.1 7 5.5 4.9 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 RR_TM4-6 PF06459.7 KUM64370.1 - 7.6 6.3 8.9 8.7 6.1 6.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mpp10 PF04006.7 KUM64370.1 - 8.1 4.6 16.0 9 4.5 11.1 1.0 1 0 0 1 1 1 0 Mpp10 protein DUF3464 PF11947.3 KUM64370.1 - 8.9 5.7 10.6 10 5.5 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Bap31 PF05529.7 KUM64370.1 - 9.2 5.6 8.4 10 5.5 5.8 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like RBP_receptor PF14752.1 KUM64371.1 - 0.075 11.3 0.2 0.1 10.9 0.1 1.1 1 0 0 1 1 1 0 Retinol binding protein receptor ATP-synt_DE_N PF02823.11 KUM64372.1 - 2.8e-20 71.8 0.1 4.1e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain PQ-loop PF04193.9 KUM64373.1 - 6.1e-34 115.3 8.7 5.9e-17 60.9 0.3 2.6 2 0 0 2 2 2 2 PQ loop repeat Cytochrom_B561 PF03188.11 KUM64374.1 - 0.00012 21.8 11.2 0.00077 19.3 7.3 2.4 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 KUM64374.1 - 0.58 9.7 4.9 2.1 7.9 3.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) Abhydrolase_6 PF12697.2 KUM64375.1 - 1.5e-05 25.0 0.0 1.8e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KUM64375.1 - 7.8e-05 22.3 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KUM64375.1 - 8.6e-05 22.3 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KUM64375.1 - 0.00069 18.9 0.3 0.0031 16.8 0.2 1.9 1 1 0 1 1 1 1 Putative serine esterase (DUF676) zf-C2H2_4 PF13894.1 KUM64376.1 - 0.0044 17.2 20.0 0.13 12.6 0.1 3.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KUM64376.1 - 0.0052 17.0 0.1 0.0052 17.0 0.1 3.6 2 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2 PF00096.21 KUM64377.1 - 0.0016 18.6 8.9 1.3 9.4 0.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KUM64377.1 - 0.0054 16.9 4.3 0.36 11.2 0.1 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KUM64377.1 - 0.006 16.8 9.8 2 8.9 0.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger Sec23_trunk PF04811.10 KUM64379.1 - 3.8e-81 272.0 0.0 5.4e-81 271.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KUM64379.1 - 1.6e-33 114.2 0.0 3.1e-33 113.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KUM64379.1 - 1.3e-29 102.5 0.0 2.7e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KUM64379.1 - 1.3e-15 56.6 6.7 2.9e-15 55.5 4.6 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KUM64379.1 - 3.2e-12 45.9 0.0 7.4e-12 44.7 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Proteasome PF00227.21 KUM64380.1 - 4e-50 169.7 0.1 5.5e-50 169.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KUM64380.1 - 5.6e-13 47.9 0.3 8.9e-13 47.2 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3650 PF12368.3 KUM64380.1 - 0.34 10.4 3.6 0.17 11.4 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) DUF2373 PF10180.4 KUM64381.1 - 1.3e-21 75.8 0.2 2.5e-21 74.9 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) TraC PF07820.7 KUM64382.1 - 0.097 12.8 0.4 0.55 10.4 0.1 2.0 1 1 1 2 2 2 0 TraC-like protein Aft1_HRA PF11786.3 KUM64383.1 - 3.6e-29 100.8 11.5 3.6e-29 100.8 8.0 2.8 3 0 0 3 3 3 1 Aft1 HRA domain Aft1_HRR PF11787.3 KUM64383.1 - 4.2e-21 75.7 6.6 4.2e-21 75.7 4.6 4.1 3 1 0 3 3 3 1 Aft1 HRR domain Aft1_OSA PF11785.3 KUM64383.1 - 4.4e-21 75.1 10.7 4.4e-21 75.1 7.4 4.1 3 1 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.16 KUM64383.1 - 1.5e-13 50.4 5.4 3.1e-13 49.4 3.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KUM64383.1 - 1.8e-06 27.6 6.1 4.8e-06 26.2 4.2 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KUM64383.1 - 0.0034 17.6 2.6 0.0034 17.6 1.8 2.5 3 0 0 3 3 3 1 bZIP Maf transcription factor Shugoshin_N PF07558.6 KUM64383.1 - 0.26 11.0 2.4 0.46 10.2 0.5 2.4 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region FLO_LFY PF01698.11 KUM64383.1 - 1.4 7.7 8.9 1.9 7.2 6.2 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Macoilin PF09726.4 KUM64383.1 - 5.8 5.0 14.2 11 4.2 9.8 1.4 1 0 0 1 1 1 0 Transmembrane protein Transthyretin PF00576.16 KUM64384.1 - 3.1e-21 75.3 0.0 1.8e-19 69.6 0.0 2.2 1 1 0 1 1 1 1 HIUase/Transthyretin family Spc97_Spc98 PF04130.8 KUM64385.1 - 1.5e-122 409.7 0.0 2e-122 409.2 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Fringe PF02434.11 KUM64386.1 - 6.1e-07 28.9 0.0 1e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Fringe-like PAN_4 PF14295.1 KUM64386.1 - 0.00028 20.5 0.7 0.00082 19.0 0.5 1.8 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 KUM64386.1 - 0.0019 17.9 0.1 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.6 KUM64386.1 - 0.025 14.4 0.2 0.081 12.7 0.1 1.8 2 0 0 2 2 2 0 PAN-like domain ubiquitin PF00240.18 KUM64387.1 - 1.9e-34 116.8 0.9 3.6e-34 115.9 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 KUM64387.1 - 6.5e-28 96.3 1.9 1.2e-27 95.5 1.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 KUM64387.1 - 8e-20 70.3 0.7 1.4e-19 69.5 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KUM64387.1 - 4e-06 26.9 0.4 1.8e-05 24.8 0.3 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KUM64387.1 - 0.00016 21.4 0.0 0.00023 20.9 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KUM64387.1 - 0.0014 18.5 0.6 0.003 17.4 0.4 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KUM64387.1 - 0.0046 17.1 0.4 0.0063 16.6 0.3 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Plexin_cytopl PF08337.7 KUM64387.1 - 0.013 13.8 0.3 1.4 7.1 0.1 2.1 2 0 0 2 2 2 0 Plexin cytoplasmic RasGAP domain IBR PF01485.16 KUM64387.1 - 0.022 14.6 0.4 0.037 13.9 0.3 1.4 1 0 0 1 1 1 0 IBR domain DUF2870 PF11069.3 KUM64387.1 - 0.06 13.3 0.2 0.18 11.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Glyco_hydro_18 PF00704.23 KUM64388.1 - 1.6e-99 333.6 0.5 1.9e-99 333.3 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 NIF PF03031.13 KUM64389.1 - 1.1e-29 103.1 0.3 2.3e-29 102.0 0.0 1.6 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 KUM64389.1 - 3e-10 39.7 0.0 6.1e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KUM64389.1 - 2.3e-08 34.0 0.0 1.2e-07 31.7 0.0 2.2 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain Biotin_lipoyl PF00364.17 KUM64389.1 - 0.022 14.3 0.0 4.3 7.0 0.0 2.6 2 0 0 2 2 2 0 Biotin-requiring enzyme MARVEL PF01284.18 KUM64390.1 - 0.0078 16.0 14.5 0.012 15.3 10.1 1.3 1 0 0 1 1 1 1 Membrane-associating domain Papilloma_E5A PF05776.7 KUM64390.1 - 1.1 9.4 12.8 0.12 12.5 5.3 2.0 2 1 0 2 2 2 0 Papillomavirus E5A protein Oxidored_q3 PF00499.15 KUM64390.1 - 3.3 7.4 16.3 5.9 6.6 11.3 1.4 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Arginase PF00491.16 KUM64391.1 - 3.2e-78 262.8 0.4 3.7e-78 262.6 0.3 1.0 1 0 0 1 1 1 1 Arginase family GatB_N PF02934.10 KUM64392.1 - 7.1e-102 340.1 0.0 9.9e-102 339.6 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 KUM64392.1 - 3.7e-26 91.6 0.0 7.7e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 GatB domain Vitellogenin_N PF01347.17 KUM64392.1 - 0.051 11.8 0.0 0.08 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipoprotein amino terminal region Synthase_beta PF11421.3 KUM64393.1 - 0.045 14.4 0.2 3.1 8.5 0.0 2.1 2 0 0 2 2 2 0 ATP synthase F1 beta subunit Sds3 PF08598.6 KUM64394.1 - 0.01 15.3 0.2 0.01 15.3 0.1 1.9 2 0 0 2 2 2 0 Sds3-like Bromodomain PF00439.20 KUM64395.1 - 0.058 13.3 0.1 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 Bromodomain PPR_3 PF13812.1 KUM64396.1 - 0.073 13.3 5.5 15 6.1 0.1 5.2 6 0 0 6 6 6 0 Pentatricopeptide repeat domain ECH PF00378.15 KUM64397.1 - 3e-48 164.1 0.1 3.7e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Abhydrolase_6 PF12697.2 KUM64398.1 - 7.7e-07 29.2 0.0 1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KUM64398.1 - 3.3e-05 23.2 0.7 0.00026 20.3 0.5 2.0 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KUM64398.1 - 0.009 15.6 0.0 0.015 14.9 0.0 1.7 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KUM64398.1 - 0.027 14.2 0.0 0.05 13.3 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family YyzF PF14116.1 KUM64398.1 - 0.12 12.3 0.1 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 YyzF-like protein DUF155 PF02582.9 KUM64399.1 - 3.9e-43 147.3 0.0 5.7e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Img2 PF05046.9 KUM64400.1 - 1.5e-25 89.1 0.0 2.3e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) eIF3_N PF09440.5 KUM64401.1 - 5.3e-51 172.2 2.2 1.2e-50 171.1 1.5 1.6 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 KUM64401.1 - 5.8e-14 52.2 0.0 2.1e-13 50.4 0.0 2.0 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 KUM64401.1 - 0.018 14.8 0.0 0.049 13.4 0.0 1.7 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 Cortex-I_coil PF09304.5 KUM64401.1 - 0.096 12.7 2.3 0.28 11.2 1.3 2.0 2 0 0 2 2 2 0 Cortexillin I, coiled coil ARID PF01388.16 KUM64402.1 - 3.9e-20 71.5 0.0 1.5e-19 69.6 0.0 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain AAA PF00004.24 KUM64403.1 - 1.7e-46 157.6 0.1 6e-46 155.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KUM64403.1 - 3.2e-09 36.6 0.6 1.1e-08 34.9 0.1 2.2 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KUM64403.1 - 4.2e-09 36.5 0.0 8.8e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KUM64403.1 - 2e-07 31.2 0.0 6.6e-07 29.4 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KUM64403.1 - 2.3e-06 27.7 2.3 0.00011 22.3 0.5 2.7 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 KUM64403.1 - 1.7e-05 24.6 0.0 6.5e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 KUM64403.1 - 5.4e-05 22.2 0.0 0.0001 21.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KUM64403.1 - 0.00022 22.0 0.1 0.0012 19.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KUM64403.1 - 0.00046 19.3 0.0 0.0011 18.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 KUM64403.1 - 0.00065 19.4 0.9 0.056 13.0 0.0 3.2 3 1 0 3 3 3 1 NACHT domain NTPase_1 PF03266.10 KUM64403.1 - 0.00067 19.4 0.0 0.002 17.8 0.0 1.8 2 0 0 2 2 1 1 NTPase Zeta_toxin PF06414.7 KUM64403.1 - 0.00073 18.6 0.1 0.0019 17.3 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 KUM64403.1 - 0.0011 18.8 0.0 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KUM64403.1 - 0.0012 18.5 0.2 0.0035 17.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 KUM64403.1 - 0.0012 18.9 0.0 0.0025 17.9 0.0 1.5 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 KUM64403.1 - 0.002 16.8 0.0 0.0038 16.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_28 PF13521.1 KUM64403.1 - 0.0023 17.9 0.0 0.0051 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KUM64403.1 - 0.0032 17.0 0.0 0.0093 15.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 KUM64403.1 - 0.0042 17.4 0.2 0.47 10.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KUM64403.1 - 0.0043 16.6 0.2 0.019 14.5 0.0 2.0 2 1 1 3 3 3 1 AAA domain Sigma54_activat PF00158.21 KUM64403.1 - 0.0049 16.3 0.1 0.2 11.1 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 KUM64403.1 - 0.0065 15.6 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 KUM64403.1 - 0.0066 16.0 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KUM64403.1 - 0.011 15.1 0.4 0.031 13.7 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 KUM64403.1 - 0.012 15.2 1.1 0.13 11.9 0.0 2.5 2 1 0 3 3 3 0 Archaeal ATPase UPF0079 PF02367.12 KUM64403.1 - 0.014 14.9 0.0 0.037 13.6 0.0 1.6 1 1 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 KUM64403.1 - 0.015 14.6 2.6 0.066 12.6 0.1 2.5 2 1 0 3 3 3 0 AAA domain Bac_DnaA PF00308.13 KUM64403.1 - 0.027 14.0 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_18 PF13238.1 KUM64403.1 - 0.028 14.7 0.0 0.086 13.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain Cast PF10174.4 KUM64403.1 - 0.029 12.4 1.0 0.056 11.4 0.4 1.5 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone AAA_30 PF13604.1 KUM64403.1 - 0.043 13.4 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KUM64403.1 - 0.058 12.5 0.9 0.75 8.8 0.0 2.5 3 0 0 3 3 3 0 KaiC Sigma54_activ_2 PF14532.1 KUM64403.1 - 0.079 13.0 0.0 0.4 10.7 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 KUM64403.1 - 0.12 12.6 0.1 0.47 10.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter NB-ARC PF00931.17 KUM64403.1 - 0.14 10.9 0.0 0.26 10.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Viral_Hsp90 PF03225.9 KUM64403.1 - 0.14 10.3 0.0 0.22 9.7 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Parvo_NS1 PF01057.12 KUM64403.1 - 0.16 10.7 0.0 0.3 9.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Asp PF00026.18 KUM64405.1 - 1.7e-109 365.9 0.1 2e-109 365.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KUM64405.1 - 3.3e-12 46.6 0.1 9.2e-12 45.2 0.1 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KUM64405.1 - 2.5e-06 27.8 0.1 0.031 14.7 0.0 3.3 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 KUM64405.1 - 6e-05 22.6 0.0 0.00096 18.7 0.0 2.4 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Peptidase_M20 PF01546.23 KUM64406.1 - 8.9e-12 44.9 0.0 1.6e-11 44.1 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KUM64406.1 - 1.3e-08 34.5 0.0 2.7e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Pex14_N PF04695.8 KUM64407.1 - 0.027 14.4 2.0 0.037 14.0 1.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ArsA_ATPase PF02374.10 KUM64408.1 - 6.9e-115 383.2 0.1 7.9e-115 383.0 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 KUM64408.1 - 3.3e-17 62.5 0.4 5.6e-17 61.7 0.2 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KUM64408.1 - 2e-08 34.3 0.0 2.6e-07 30.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 KUM64408.1 - 1.4e-06 27.6 0.1 3.7e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 KUM64408.1 - 3.3e-05 23.4 1.3 0.00067 19.1 0.0 2.8 3 1 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 KUM64408.1 - 0.0073 15.7 0.3 0.023 14.0 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KUM64408.1 - 0.011 15.5 0.0 0.035 13.8 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain PhoH PF02562.11 KUM64408.1 - 0.012 14.9 0.1 0.031 13.5 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein MipZ PF09140.6 KUM64408.1 - 0.014 14.5 0.1 0.042 12.9 0.0 1.8 2 0 0 2 2 2 0 ATPase MipZ IstB_IS21 PF01695.12 KUM64408.1 - 0.022 14.1 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein YhjQ PF06564.7 KUM64408.1 - 0.026 13.8 0.0 0.065 12.5 0.0 1.6 2 0 0 2 2 2 0 YhjQ protein T2SE PF00437.15 KUM64408.1 - 0.076 11.8 0.1 0.23 10.3 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.17 KUM64408.1 - 0.088 11.6 0.1 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AIP3 PF03915.8 KUM64408.1 - 0.12 11.2 0.1 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 A1_Propeptide PF07966.7 KUM64408.1 - 0.43 10.4 0.1 0.43 10.4 0.1 2.4 3 0 0 3 3 3 0 A1 Propeptide Ribonuclease_T2 PF00445.13 KUM64409.1 - 1.5e-46 158.4 0.0 2.7e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family zf-H2C2_2 PF13465.1 KUM64410.1 - 1.5e-10 40.8 4.2 0.00013 22.0 0.1 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 KUM64410.1 - 1.7e-06 27.9 17.8 0.00087 19.4 2.9 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KUM64410.1 - 0.001 19.2 14.4 0.018 15.3 1.3 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KUM64410.1 - 0.0011 19.0 5.3 0.0033 17.5 1.8 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KUM64410.1 - 0.15 12.0 5.8 0.63 10.0 0.0 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 KUM64410.1 - 0.15 11.7 5.5 0.12 12.1 2.6 1.7 1 1 0 1 1 1 0 BED zinc finger Bunya_G2 PF03563.8 KUM64410.1 - 0.18 10.6 0.6 0.32 9.8 0.4 1.3 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 Metallopep PF12044.3 KUM64411.1 - 1e-177 590.8 0.0 1.2e-177 590.5 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 KUM64411.1 - 0.00021 21.1 0.0 0.001 18.9 0.0 2.1 1 1 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_5 PF13688.1 KUM64411.1 - 0.02 14.8 0.4 0.036 13.9 0.3 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KUM64411.1 - 0.06 13.3 0.2 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF605 PF04652.11 KUM64411.1 - 8.8 5.6 7.9 14 4.9 5.4 1.2 1 0 0 1 1 1 0 Vta1 like CP2 PF04516.10 KUM64412.1 - 2e-83 279.0 0.0 3e-83 278.4 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor DUF4320 PF14208.1 KUM64412.1 - 0.21 11.5 0.0 0.89 9.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4320) Abhydrolase_6 PF12697.2 KUM64413.1 - 9.6e-16 58.3 0.0 1.4e-15 57.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM64413.1 - 4.9e-14 52.4 0.0 6.1e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KUM64413.1 - 5.5e-11 42.4 0.0 8.8e-11 41.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KUM64413.1 - 1.1e-05 25.1 0.0 2.5e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold UPF0227 PF05728.7 KUM64413.1 - 1.5e-05 24.7 0.0 0.00032 20.4 0.0 2.2 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) Peptidase_S9 PF00326.16 KUM64413.1 - 0.00011 21.4 0.0 0.03 13.5 0.0 2.3 1 1 0 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.8 KUM64413.1 - 0.0033 16.9 0.0 0.092 12.1 0.0 2.3 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Thioesterase PF00975.15 KUM64413.1 - 0.053 13.7 0.0 0.08 13.1 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.15 KUM64413.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Clathrin PF00637.15 KUM64415.1 - 5.3e-19 68.2 0.1 1.7e-18 66.6 0.0 1.8 1 0 0 1 1 1 1 Region in Clathrin and VPS WD40 PF00400.27 KUM64415.1 - 0.00016 21.4 1.0 0.076 12.9 0.3 3.9 3 1 0 3 3 3 1 WD domain, G-beta repeat zf-RING_5 PF14634.1 KUM64415.1 - 0.052 13.2 0.3 0.1 12.3 0.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Vps39_1 PF10366.4 KUM64415.1 - 0.1 12.6 0.1 0.42 10.6 0.0 2.0 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Oxidored_FMN PF00724.15 KUM64416.1 - 1.7e-66 224.5 0.0 2.2e-66 224.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.16 KUM64416.1 - 1.2e-05 24.7 0.0 2.1e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein PcrB PF01884.12 KUM64416.1 - 0.0011 18.3 0.0 0.0019 17.4 0.0 1.4 1 0 0 1 1 1 1 PcrB family NMO PF03060.10 KUM64416.1 - 0.0014 17.9 0.6 0.0022 17.1 0.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Dus PF01207.12 KUM64416.1 - 0.0017 17.2 0.6 0.0025 16.7 0.0 1.5 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 KUM64416.1 - 0.0023 16.9 0.1 0.0044 16.0 0.1 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 KUM64416.1 - 0.0055 15.5 0.6 0.0084 14.9 0.1 1.5 2 0 0 2 2 2 1 FMN-dependent dehydrogenase RNA_pol_Rpo13 PF12136.3 KUM64416.1 - 0.058 13.1 0.4 0.12 12.0 0.1 1.6 2 0 0 2 2 2 0 RNA polymerase Rpo13 subunit HTH domain F_bP_aldolase PF01116.15 KUM64416.1 - 0.09 11.8 0.0 0.19 10.7 0.0 1.5 2 0 0 2 2 2 0 Fructose-bisphosphate aldolase class-II NB-ARC PF00931.17 KUM64417.1 - 3e-12 46.0 0.1 4.4e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 KUM64417.1 - 1.1e-06 28.7 0.0 2.5e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KUM64417.1 - 7.5e-05 22.8 0.0 0.00016 21.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KUM64417.1 - 0.00032 20.3 0.2 0.00091 18.9 0.0 1.8 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.7 KUM64417.1 - 0.0012 17.9 0.0 0.0025 16.9 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin KaiC PF06745.8 KUM64417.1 - 0.0019 17.3 0.0 0.0047 16.0 0.0 1.6 2 0 0 2 2 2 1 KaiC AAA_33 PF13671.1 KUM64417.1 - 0.018 14.8 0.1 0.045 13.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KUM64417.1 - 0.026 15.3 0.0 0.056 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KUM64417.1 - 0.029 14.0 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_10 PF12846.2 KUM64417.1 - 0.056 12.8 0.0 0.093 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_19 PF13245.1 KUM64417.1 - 0.059 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain RuvB_N PF05496.7 KUM64417.1 - 0.068 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 KUM64417.1 - 0.087 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Uroplakin_II PF07353.7 KUM64418.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Uroplakin II DIOX_N PF14226.1 KUM64419.1 - 1.7e-26 92.9 0.1 2.8e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KUM64419.1 - 5e-19 68.4 0.0 1.1e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.10 KUM64420.1 - 3.5e-102 342.2 29.1 4.1e-102 341.9 20.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ADC PF06314.6 KUM64421.1 - 5.5e-44 150.2 0.0 6.9e-44 149.9 0.0 1.0 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) AA_permease PF00324.16 KUM64422.1 - 2.1e-100 336.3 36.8 2.6e-100 336.0 25.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KUM64422.1 - 4.7e-30 104.4 40.2 5.9e-30 104.1 27.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1612 PF07756.7 KUM64422.1 - 0.042 13.9 2.1 0.46 10.5 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1612) DUF1749 PF08538.5 KUM64423.1 - 1.4e-94 316.3 0.0 1.7e-94 316.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 KUM64423.1 - 6.9e-09 35.9 0.2 1.1e-08 35.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM64423.1 - 1.2e-05 25.1 0.0 1.9e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Exo_endo_phos PF03372.18 KUM64424.1 - 2.4e-18 66.9 1.9 3.6e-18 66.3 1.3 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KUM64424.1 - 0.00077 19.0 0.2 0.004 16.7 0.0 2.4 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase BACON PF13004.2 KUM64424.1 - 0.007 16.5 1.5 0.29 11.3 0.8 2.5 2 0 0 2 2 2 1 Bacteroidetes-Associated Carbohydrate-binding Often N-terminal COesterase PF00135.23 KUM64425.1 - 3.5e-67 227.3 0.0 1.6e-65 221.8 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family F-box-like PF12937.2 KUM64426.1 - 1.6e-06 27.6 0.3 2.2e-05 24.0 0.1 2.6 2 0 0 2 2 2 1 F-box-like Ras PF00071.17 KUM64428.1 - 1.4e-51 174.0 0.6 7.8e-51 171.6 0.4 1.8 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KUM64428.1 - 4.4e-16 59.4 0.1 2.4e-14 53.8 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KUM64428.1 - 0.00044 19.5 0.1 0.0034 16.6 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family FeoB_N PF02421.13 KUM64428.1 - 0.01 15.1 0.2 0.17 11.1 0.0 2.4 2 1 1 3 3 3 0 Ferrous iron transport protein B MMR_HSR1 PF01926.18 KUM64428.1 - 0.013 15.4 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.5 KUM64428.1 - 0.024 13.8 0.1 0.57 9.3 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_25 PF13481.1 KUM64428.1 - 0.06 12.7 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 KUM64428.1 - 0.081 12.0 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Septin PF00735.13 KUM64428.1 - 0.15 11.0 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Septin AMP-binding PF00501.23 KUM64429.1 - 3.8e-79 266.0 0.0 4.6e-79 265.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KUM64429.1 - 3.7e-13 50.2 0.2 1.1e-12 48.6 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.20 KUM64430.1 - 6.5e-35 120.5 0.0 1.3e-34 119.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM64430.1 - 3.1e-12 46.1 0.0 6.3e-06 25.4 0.0 3.1 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 KUM64430.1 - 0.089 12.5 0.0 1.3 8.7 0.0 2.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family HNH_2 PF13391.1 KUM64431.1 - 0.055 13.2 0.1 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 HNH endonuclease Cyclin PF08613.6 KUM64432.1 - 8.6e-32 110.6 0.0 9.5e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KUM64432.1 - 0.00085 18.8 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF1731 PF08338.6 KUM64432.1 - 0.044 13.2 0.0 0.092 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) hDGE_amylase PF14701.1 KUM64433.1 - 0.023 13.6 2.0 0.053 12.4 1.3 1.7 2 0 0 2 2 2 0 glucanotransferase domain of human glycogen debranching enzyme PALP PF00291.20 KUM64434.1 - 2e-57 194.7 0.1 2.6e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 KUM64434.1 - 6.5e-08 32.2 0.1 7.2e-06 25.7 0.0 2.7 3 0 0 3 3 3 2 CBS domain Na_Ca_ex PF01699.19 KUM64435.1 - 5e-23 81.2 22.7 2.5e-14 53.0 3.2 2.4 2 1 0 2 2 2 2 Sodium/calcium exchanger protein DUF202 PF02656.10 KUM64435.1 - 0.0061 16.7 9.2 1.9 8.7 0.1 3.8 4 0 0 4 4 4 3 Domain of unknown function (DUF202) PhoQ_Sensor PF08918.5 KUM64435.1 - 0.092 12.2 0.3 0.25 10.8 0.1 1.9 1 1 0 1 1 1 0 PhoQ Sensor GPI-anchored PF10342.4 KUM64436.1 - 1.5e-06 28.5 0.2 1.5e-06 28.5 0.1 2.2 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family KRE9 PF05390.6 KUM64436.1 - 0.00084 19.6 5.2 0.00084 19.6 3.6 2.0 2 0 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 SRPRB PF09439.5 KUM64437.1 - 2.1e-23 82.4 3.2 8.3e-22 77.2 2.2 2.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 KUM64437.1 - 7.7e-05 22.7 1.0 0.00038 20.5 0.7 2.2 1 1 0 1 1 1 1 AAA ATPase domain Arf PF00025.16 KUM64437.1 - 0.00025 20.3 0.1 0.0039 16.4 0.0 2.3 2 1 0 2 2 2 1 ADP-ribosylation factor family AAA_29 PF13555.1 KUM64437.1 - 0.0041 16.6 0.8 0.014 14.9 0.2 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain Sigma54_activat PF00158.21 KUM64437.1 - 0.019 14.4 0.0 0.83 9.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain ATP_bind_1 PF03029.12 KUM64437.1 - 0.023 14.2 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.12 KUM64437.1 - 0.049 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.22 KUM64437.1 - 0.05 13.9 0.1 0.11 12.8 0.1 1.8 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 KUM64437.1 - 0.051 13.7 0.7 0.14 12.2 0.1 2.0 1 1 1 2 2 2 0 AAA domain DUF258 PF03193.11 KUM64437.1 - 0.072 12.2 0.1 0.2 10.8 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Peptidase_M76 PF09768.4 KUM64438.1 - 5.1e-73 244.1 2.2 6.1e-73 243.9 1.5 1.1 1 0 0 1 1 1 1 Peptidase M76 family ECR1_N PF14382.1 KUM64438.1 - 0.028 13.7 0.0 0.064 12.5 0.0 1.5 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region E6 PF00518.12 KUM64438.1 - 0.049 13.9 1.6 1.6 9.0 0.2 2.4 2 1 0 2 2 2 0 Early Protein (E6) SprT-like PF10263.4 KUM64438.1 - 6.7 6.3 9.0 4.5 6.9 3.8 2.4 2 1 0 2 2 2 0 SprT-like family AA_kinase PF00696.23 KUM64439.1 - 2.7e-38 131.8 0.7 5e-38 131.0 0.5 1.4 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 KUM64439.1 - 1.5e-15 56.6 0.1 1.8e-14 53.2 0.0 2.3 2 0 0 2 2 2 1 PUA domain Pkinase PF00069.20 KUM64441.1 - 6.3e-64 215.6 0.1 2.2e-63 213.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM64441.1 - 8.3e-42 143.0 0.0 1.1e-41 142.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM64441.1 - 1.4e-07 30.8 0.0 4.8e-07 29.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KUM64441.1 - 3.2e-05 23.0 0.1 5.4e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KUM64441.1 - 0.018 14.3 0.1 0.043 13.1 0.1 1.7 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 KUM64441.1 - 0.042 13.5 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glyco_trans_4_2 PF13477.1 KUM64443.1 - 0.078 12.8 0.4 0.15 11.8 0.3 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like NdhL PF10716.4 KUM64443.1 - 0.35 10.6 4.9 0.21 11.3 1.4 2.2 1 1 0 1 1 1 0 NADH dehydrogenase transmembrane subunit Abhydrolase_9_N PF15420.1 KUM64443.1 - 1.1 8.9 5.2 2.5 7.7 3.6 1.5 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus E1-E2_ATPase PF00122.15 KUM64443.1 - 5.5 5.9 9.5 13 4.6 0.0 2.5 2 1 0 2 2 2 0 E1-E2 ATPase DUF3796 PF12676.2 KUM64443.1 - 7.3 6.8 10.0 0.31 11.2 0.8 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3796) Transferase PF02458.10 KUM64444.1 - 2.4e-17 62.5 0.0 1.1e-13 50.4 0.0 2.1 2 0 0 2 2 2 2 Transferase family HeH PF12949.2 KUM64445.1 - 0.035 13.6 0.0 0.59 9.7 0.0 2.4 2 0 0 2 2 2 0 HeH/LEM domain DUF4246 PF14033.1 KUM64447.1 - 4.5e-170 566.5 0.3 5.2e-170 566.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Cytochrom_B562 PF07361.6 KUM64448.1 - 0.11 12.8 0.4 0.35 11.2 0.0 1.9 2 0 0 2 2 2 0 Cytochrome b562 Cyt-b5 PF00173.23 KUM64449.1 - 7.7e-20 70.4 0.1 8.6e-20 70.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.3 KUM64449.1 - 0.046 13.6 0.0 0.058 13.3 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H OB_NTP_bind PF07717.11 KUM64450.1 - 6.5e-30 103.2 0.0 1.6e-29 101.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KUM64450.1 - 2.5e-25 88.4 2.0 4.3e-25 87.6 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KUM64450.1 - 3.2e-12 46.1 0.0 7.3e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KUM64450.1 - 3.5e-06 26.6 0.3 1.9e-05 24.1 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase T2SE PF00437.15 KUM64450.1 - 1.8e-05 23.7 0.0 4.1e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 KUM64450.1 - 5.1e-05 23.4 0.8 0.0002 21.5 0.0 2.3 3 0 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.1 KUM64450.1 - 0.0044 17.0 0.0 0.017 15.1 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_30 PF13604.1 KUM64450.1 - 0.011 15.3 0.1 0.011 15.3 0.0 2.4 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.1 KUM64450.1 - 0.011 15.4 0.3 0.084 12.6 0.0 2.6 3 0 0 3 3 3 0 Part of AAA domain AAA_29 PF13555.1 KUM64450.1 - 0.044 13.3 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 KUM64450.1 - 0.085 13.1 0.0 0.085 13.1 0.0 3.6 1 1 0 2 2 1 0 AAA domain Flavi_DEAD PF07652.9 KUM64450.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain HAD_2 PF13419.1 KUM64451.1 - 4.6e-22 79.0 0.1 9.4e-22 78.0 0.1 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KUM64451.1 - 0.00013 22.4 0.0 0.00021 21.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KUM64451.1 - 0.00018 21.1 0.0 0.00036 20.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Mcp5_PH PF12814.2 KUM64452.1 - 5.8e-47 158.6 0.0 1.3e-46 157.5 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology TPR_MLP1_2 PF07926.7 KUM64452.1 - 0.0011 18.6 14.9 0.0087 15.8 4.9 2.4 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein IncA PF04156.9 KUM64452.1 - 0.0031 17.1 5.8 0.0061 16.1 3.5 1.8 2 0 0 2 2 2 1 IncA protein GldM_N PF12081.3 KUM64452.1 - 0.091 12.2 2.7 0.14 11.6 1.9 1.3 1 0 0 1 1 1 0 GldM N-terminal domain Fib_alpha PF08702.5 KUM64452.1 - 0.16 12.0 2.1 1.3 9.1 0.5 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family GAS PF13851.1 KUM64452.1 - 0.38 9.9 13.4 3.1 6.9 9.3 1.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 KUM64452.1 - 2.4 8.0 14.0 4.8 7.0 9.7 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 KUM64452.1 - 3.4 7.2 5.5 6.1 6.3 0.2 3.5 2 2 1 3 3 3 0 Septum formation initiator APG6 PF04111.7 KUM64452.1 - 3.9 6.4 10.0 6.4 5.7 6.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 ERM PF00769.14 KUM64452.1 - 5.3 6.4 18.1 6.9 6.1 9.2 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Spc7 PF08317.6 KUM64452.1 - 8.5 4.9 10.9 14 4.2 7.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein AMP-binding PF00501.23 KUM64453.1 - 2.4e-204 678.4 0.0 8.2e-92 307.7 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 KUM64453.1 - 9.5e-202 668.2 4.8 6.7e-40 136.7 0.1 6.4 6 0 0 6 6 6 6 Condensation domain PP-binding PF00550.20 KUM64453.1 - 7.3e-54 179.9 13.5 3.1e-11 43.3 0.0 7.0 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KUM64453.1 - 4.2e-15 56.4 0.0 1.6e-06 28.9 0.0 3.9 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.11 KUM64453.1 - 1.2e-06 28.3 0.0 0.84 9.1 0.0 4.2 4 0 0 4 4 4 3 Wax ester synthase-like Acyl-CoA acyltransferase domain AATase PF07247.7 KUM64453.1 - 0.022 13.3 0.1 15 3.9 0.0 4.4 4 1 0 4 4 4 0 Alcohol acetyltransferase Musclin PF11037.3 KUM64454.1 - 0.068 12.7 0.2 0.068 12.7 0.2 1.8 2 1 0 2 2 2 0 Insulin-resistance promoting peptide in skeletal muscle Herpes_DNAp_acc PF04929.7 KUM64454.1 - 0.15 11.0 5.5 0.55 9.1 3.9 1.7 1 1 0 1 1 1 0 Herpes DNA replication accessory factor Med19 PF10278.4 KUM64454.1 - 5.2 6.7 22.5 0.67 9.6 5.0 2.1 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 BLVR PF06375.6 KUM64454.1 - 8.1 6.2 23.3 2.2 8.1 6.5 2.5 2 1 1 3 3 3 0 Bovine leukaemia virus receptor (BLVR) Pkinase PF00069.20 KUM64455.1 - 2e-40 138.6 0.0 4.1e-40 137.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM64455.1 - 2.1e-23 82.7 0.0 4.6e-23 81.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM64455.1 - 0.012 14.5 0.0 0.034 13.1 0.0 1.6 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 KUM64455.1 - 0.099 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KUM64455.1 - 0.34 9.6 0.0 0.49 9.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase K_oxygenase PF13434.1 KUM64456.1 - 6.1e-109 364.0 0.0 8.6e-109 363.5 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KUM64456.1 - 1.6e-12 47.9 0.0 5e-09 36.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM64456.1 - 1.1e-05 25.2 0.0 0.0029 17.4 0.0 3.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KUM64456.1 - 1.9e-05 24.6 0.0 0.0051 16.7 0.0 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DUF269 PF03270.8 KUM64456.1 - 0.098 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF269 Ank_2 PF12796.2 KUM64457.1 - 1.9e-50 169.1 0.1 9.7e-16 57.8 0.0 3.5 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) zf-DHHC PF01529.15 KUM64457.1 - 1.7e-39 135.0 6.2 1.7e-39 135.0 4.3 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase Ank PF00023.25 KUM64457.1 - 2e-33 112.5 1.8 9.8e-10 37.7 0.0 5.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 KUM64457.1 - 2.3e-28 97.5 3.4 2.1e-08 34.1 0.0 5.1 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM64457.1 - 3.4e-23 79.4 2.1 5.7e-08 32.2 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 KUM64457.1 - 4e-22 78.1 10.9 1.6e-08 34.8 0.2 4.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) DUF1430 PF07242.6 KUM64457.1 - 0.035 14.1 0.9 0.035 14.1 0.6 2.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1430) Toxin_5 PF05294.8 KUM64457.1 - 2.9 8.1 6.3 6.3 7.1 4.4 1.6 1 0 0 1 1 1 0 Scorpion short toxin TIP41 PF04176.8 KUM64458.1 - 9.7e-79 262.8 0.0 1.2e-78 262.5 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family Ubiq_cyt_C_chap PF03981.7 KUM64459.1 - 2.9e-37 127.6 0.1 1.5e-36 125.3 0.1 1.9 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone Peptidase_M1 PF01433.15 KUM64460.1 - 1.1e-74 251.9 0.0 1.3e-74 251.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 KUM64460.1 - 6.7e-25 87.3 0.0 3.8e-24 84.9 0.0 2.0 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 KUM64460.1 - 9.1e-18 64.5 0.1 1.5e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 KUM64460.1 - 0.036 14.0 2.3 0.42 10.5 1.5 2.6 2 1 0 2 2 2 0 M61 glycyl aminopeptidase MIT PF04212.13 KUM64461.1 - 5.1e-09 35.8 0.2 5.1e-09 35.8 0.1 2.2 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Pou PF00157.12 KUM64461.1 - 0.14 11.8 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain Eaf7 PF07904.8 KUM64462.1 - 2.9e-29 100.8 0.0 4.8e-29 100.1 0.0 1.3 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 Nop14 PF04147.7 KUM64462.1 - 1.1 7.0 7.1 1.3 6.8 4.9 1.2 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 KUM64462.1 - 6.2 5.8 10.2 12 4.9 7.0 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Spc97_Spc98 PF04130.8 KUM64463.1 - 9.6e-75 251.9 0.2 1.3e-74 251.5 0.1 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Rieske_2 PF13806.1 KUM64464.1 - 5.2e-18 64.6 0.0 8.2e-18 64.0 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.21 KUM64464.1 - 8e-15 54.1 0.0 1.4e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain MFS_1 PF07690.11 KUM64465.1 - 1e-29 103.3 41.5 1.2e-28 99.9 15.4 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Mo-co_dimer PF03404.11 KUM64466.1 - 2.7e-54 182.3 0.1 6.3e-54 181.1 0.1 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 KUM64466.1 - 8e-46 155.5 0.0 1.4e-45 154.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 KUM64466.1 - 2.8e-31 107.5 0.0 4.9e-31 106.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KUM64466.1 - 3e-27 95.3 0.0 6.1e-27 94.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 KUM64466.1 - 6.8e-20 70.6 0.0 1.3e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 KUM64466.1 - 0.0022 17.8 0.0 0.58 10.0 0.0 2.4 1 1 0 2 2 2 2 Ferric reductase NAD binding domain Pyr_redox_2 PF07992.9 KUM64467.1 - 4.4e-30 105.0 0.6 2.8e-29 102.4 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KUM64467.1 - 1.4e-13 51.0 7.9 2.1e-13 50.4 0.4 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.10 KUM64467.1 - 3.1e-13 49.5 4.4 3.6e-12 46.1 2.7 2.6 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain NIR_SIR PF01077.17 KUM64467.1 - 2.6e-11 43.1 0.1 9.2e-11 41.3 0.0 1.9 2 0 0 2 2 2 1 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 KUM64467.1 - 4.5e-11 42.2 0.0 1.1e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_3 PF13738.1 KUM64467.1 - 2.9e-06 27.5 0.1 0.00023 21.2 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM64467.1 - 0.00038 20.2 1.4 1.1 9.0 0.0 3.4 3 1 1 4 4 4 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 KUM64467.1 - 0.019 13.9 0.0 0.26 10.1 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 KUM64467.1 - 0.033 13.0 2.6 0.036 12.9 0.0 2.2 2 1 1 3 3 3 0 FAD binding domain NAD_binding_7 PF13241.1 KUM64467.1 - 0.04 14.1 0.2 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.9 KUM64467.1 - 0.04 12.3 0.1 2.5 6.4 0.0 2.9 3 1 1 4 4 4 0 HI0933-like protein adh_short PF00106.20 KUM64468.1 - 4.8e-32 111.1 0.4 4.8e-32 111.1 0.3 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM64468.1 - 4.2e-27 95.4 0.0 5.6e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM64468.1 - 3.7e-13 49.5 0.2 6.1e-13 48.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM64468.1 - 1.1e-07 31.6 0.1 2.1e-06 27.3 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 KUM64468.1 - 0.00014 21.1 0.0 0.00019 20.6 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KUM64468.1 - 0.021 14.8 1.9 0.36 10.8 1.3 2.5 1 1 0 1 1 1 0 NADH(P)-binding DUF718 PF05336.8 KUM64470.1 - 2.6e-34 117.2 0.2 2.9e-34 117.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF718) DUF2500 PF10694.4 KUM64471.1 - 4.9 7.2 6.4 11 6.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) IU_nuc_hydro PF01156.14 KUM64472.1 - 3.8e-53 180.7 0.0 2.9e-52 177.8 0.0 1.9 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Transketolase_C PF02780.15 KUM64472.1 - 0.049 13.5 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 Transketolase, C-terminal domain Fungal_trans PF04082.13 KUM64474.1 - 3.5e-15 55.5 0.1 5.1e-15 55.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DELLA PF12041.3 KUM64474.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal SSP160 PF06933.6 KUM64475.1 - 1 7.2 7.1 1.1 7.1 4.9 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 HLH PF00010.21 KUM64476.1 - 1e-14 53.9 0.1 3.3e-14 52.3 0.1 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MFS_1 PF07690.11 KUM64477.1 - 7.5e-40 136.7 31.1 7.5e-40 136.7 21.5 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM64477.1 - 1.4e-13 50.2 5.6 1.4e-13 50.2 3.9 3.0 3 1 1 4 4 4 1 Sugar (and other) transporter Fungal_trans PF04082.13 KUM64478.1 - 0.00022 20.1 0.4 0.00047 19.1 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain CHORD PF04968.7 KUM64479.1 - 0.073 13.3 0.7 0.073 13.3 0.5 1.7 2 0 0 2 2 2 0 CHORD SOG2 PF10428.4 KUM64480.1 - 0.12 10.9 1.8 0.18 10.4 1.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF2360 PF10152.4 KUM64480.1 - 2.7 8.2 5.1 5.5 7.2 3.5 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) ABC_membrane_2 PF06472.10 KUM64481.1 - 3.2e-92 308.6 3.8 7e-79 264.8 0.3 2.3 1 1 1 2 2 2 2 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KUM64481.1 - 7.7e-19 68.3 0.0 1.5e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter HAD PF12710.2 KUM64481.1 - 6.1e-08 33.0 0.0 1.8e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_21 PF13304.1 KUM64481.1 - 0.00026 21.0 0.0 0.00076 19.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 KUM64481.1 - 0.017 15.4 0.0 0.046 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KUM64481.1 - 0.031 13.7 0.0 0.078 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Put_Phosphatase PF06888.7 KUM64481.1 - 0.036 13.2 0.0 2.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Putative Phosphatase SMC_N PF02463.14 KUM64481.1 - 0.049 12.8 0.0 0.19 10.9 0.0 1.9 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KUM64481.1 - 0.11 12.4 1.9 0.25 11.2 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain Hydrolase PF00702.21 KUM64481.1 - 0.13 12.6 0.0 1 9.6 0.0 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase DUF258 PF03193.11 KUM64481.1 - 0.21 10.7 0.0 0.45 9.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 adh_short PF00106.20 KUM64482.1 - 1.8e-13 50.7 0.1 3.3e-13 49.9 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KUM64482.1 - 0.001 18.0 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 KUM64482.1 - 0.013 15.2 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 KR domain NAD_binding_4 PF07993.7 KUM64482.1 - 0.082 11.8 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein DUF2436 PF10365.4 KUM64482.1 - 0.089 12.4 0.1 0.54 9.8 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF2436) LRR_4 PF12799.2 KUM64483.1 - 0.056 13.0 8.5 2.3 7.9 0.2 5.2 5 1 2 7 7 7 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KUM64483.1 - 0.11 12.5 5.2 2.1e+02 2.4 0.0 6.9 8 0 0 8 8 8 0 Leucine Rich repeat DUF3829 PF12889.2 KUM64484.1 - 0.0031 16.7 3.4 0.0079 15.4 2.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3829) Mnd1 PF03962.10 KUM64484.1 - 0.17 11.5 4.5 0.37 10.4 3.1 1.6 1 0 0 1 1 1 0 Mnd1 family Ribosomal_L18p PF00861.17 KUM64486.1 - 3.4e-42 143.4 0.2 6.3e-42 142.5 0.2 1.5 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 KUM64486.1 - 1e-30 106.1 9.2 1e-30 106.1 6.4 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region HAD_2 PF13419.1 KUM64486.1 - 4.9e-14 52.9 1.2 3.8e-13 50.0 0.0 2.5 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KUM64486.1 - 0.012 15.3 0.0 0.029 14.0 0.0 1.7 1 0 0 1 1 1 0 HAD-hyrolase-like MtrA PF04208.9 KUM64486.1 - 0.056 12.8 0.2 0.094 12.1 0.1 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A ORC6 PF05460.8 KUM64488.1 - 0.13 11.3 2.1 0.15 11.1 1.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Abhydrolase_6 PF12697.2 KUM64489.1 - 3.6e-33 115.3 0.9 4.6e-33 115.0 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM64489.1 - 7.7e-22 77.9 0.2 1.8e-18 66.9 0.1 2.4 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KUM64489.1 - 1.9e-16 60.1 0.1 1.6e-15 57.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KUM64489.1 - 2.8e-06 27.1 0.0 4.8e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 KUM64489.1 - 2.3e-05 23.0 0.0 3.3e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Ndr family PGAP1 PF07819.8 KUM64489.1 - 8.1e-05 22.3 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.6 KUM64489.1 - 0.0011 18.0 0.1 0.0021 17.2 0.0 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DUF2424 PF10340.4 KUM64489.1 - 0.0037 15.9 0.0 0.0052 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Esterase PF00756.15 KUM64489.1 - 0.016 14.6 0.0 0.061 12.7 0.0 1.9 2 0 0 2 2 2 0 Putative esterase UPF0227 PF05728.7 KUM64489.1 - 0.026 14.2 0.1 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Chlorophyllase2 PF12740.2 KUM64489.1 - 0.061 12.2 0.0 0.2 10.5 0.0 1.7 1 1 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_3 PF07859.8 KUM64489.1 - 0.083 12.4 0.6 0.16 11.4 0.1 1.8 2 1 0 2 2 2 0 alpha/beta hydrolase fold Chlorophyllase PF07224.6 KUM64489.1 - 0.089 11.5 0.1 0.31 9.8 0.0 1.7 1 1 0 1 1 1 0 Chlorophyllase DUF2974 PF11187.3 KUM64489.1 - 0.091 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Eno-Rase_NADH_b PF12242.3 KUM64489.1 - 0.096 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Thioesterase PF00975.15 KUM64489.1 - 0.1 12.8 0.1 0.18 11.9 0.1 1.5 1 1 0 1 1 1 0 Thioesterase domain Ser_hydrolase PF06821.8 KUM64489.1 - 0.14 11.7 0.1 0.56 9.7 0.0 1.9 1 1 1 2 2 2 0 Serine hydrolase PAF-AH_p_II PF03403.8 KUM64489.1 - 0.17 10.1 0.0 0.24 9.6 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Acyl_transf_1 PF00698.16 KUM64489.1 - 0.18 11.0 0.1 0.28 10.4 0.1 1.2 1 0 0 1 1 1 0 Acyl transferase domain BSP PF04450.7 KUM64490.1 - 3.9e-73 245.2 0.0 4.7e-73 245.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 KUM64490.1 - 0.00015 21.7 0.0 0.00033 20.7 0.0 1.6 1 1 0 1 1 1 1 Peptidase MA superfamily SprT-like PF10263.4 KUM64490.1 - 0.011 15.4 0.0 0.032 13.8 0.0 1.8 2 0 0 2 2 2 0 SprT-like family Ribonuclease_3 PF00636.21 KUM64493.1 - 2e-06 28.2 0.0 6.2e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KUM64493.1 - 4.4e-06 26.6 0.0 0.00079 19.3 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.20 KUM64493.1 - 0.0011 19.5 0.3 0.0035 17.8 0.0 2.1 2 0 0 2 2 2 1 Double-stranded RNA binding motif CAP_N PF01213.14 KUM64494.1 - 2.4e-75 253.7 21.5 1.1e-58 199.0 6.0 2.6 1 1 1 2 2 2 2 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 KUM64494.1 - 4e-57 192.0 0.2 5.5e-57 191.5 0.2 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 KUM64494.1 - 0.037 13.4 4.6 0.47 9.8 2.4 2.2 1 1 1 2 2 2 0 Tubulin binding cofactor C PfkB PF00294.19 KUM64495.1 - 4e-10 39.3 0.0 1.1e-09 37.9 0.0 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase rRNA_processing PF08524.6 KUM64496.1 - 0.00089 19.0 3.0 0.00089 19.0 2.1 2.2 1 1 0 2 2 2 1 rRNA processing DUF334 PF03904.8 KUM64496.1 - 0.041 13.1 0.1 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF334) RR_TM4-6 PF06459.7 KUM64496.1 - 2.8 7.7 10.6 3.5 7.4 7.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Trypan_PARP PF05887.6 KUM64496.1 - 6.2 6.6 12.7 2.4 7.9 7.1 1.6 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF4210 PF13915.1 KUM64497.1 - 9.3e-28 96.3 0.3 3.6e-27 94.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 KUM64497.1 - 2.4e-21 75.3 0.3 6.3e-21 74.0 0.2 1.8 1 0 0 1 1 1 1 Chromosome segregation during meiosis Iso_dh PF00180.15 KUM64498.1 - 9.7e-101 337.1 0.0 1.2e-100 336.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HHH_2 PF12826.2 KUM64498.1 - 0.1 12.4 0.1 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif Sec5 PF15469.1 KUM64499.1 - 4e-35 121.1 0.0 3.1e-34 118.3 0.0 2.3 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 KUM64499.1 - 1.4e-05 24.8 0.0 6e-05 22.7 0.0 2.1 1 0 0 1 1 1 1 Vps51/Vps67 DUF4468 PF14730.1 KUM64499.1 - 0.0048 16.5 0.1 0.14 11.8 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4468) with TBP-like fold Pyr_redox_3 PF13738.1 KUM64502.1 - 5e-26 92.0 0.4 2.1e-25 90.0 0.1 2.1 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KUM64502.1 - 2.1e-24 85.6 0.0 6.3e-24 84.0 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KUM64502.1 - 1.4e-12 47.9 0.0 5e-08 33.0 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KUM64502.1 - 1.6e-10 40.4 1.8 2e-08 33.5 0.1 3.1 3 1 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 KUM64502.1 - 2e-08 33.6 0.9 0.00046 19.3 0.3 3.2 2 1 1 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 KUM64502.1 - 1.9e-06 27.7 0.0 0.00016 21.6 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KUM64502.1 - 2e-06 28.0 0.1 0.032 14.6 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 KUM64502.1 - 2.5e-06 26.7 0.4 0.024 13.7 0.1 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 KUM64502.1 - 6.8e-05 22.6 0.1 1.1 9.0 0.0 3.5 2 1 0 2 2 2 2 FAD-NAD(P)-binding IlvN PF07991.7 KUM64502.1 - 0.00025 20.4 0.0 0.002 17.5 0.0 2.2 3 0 0 3 3 2 1 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 KUM64502.1 - 0.00027 20.6 0.2 0.036 13.7 0.1 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KUM64502.1 - 0.001 18.0 0.3 0.011 14.6 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_2 PF03446.10 KUM64502.1 - 0.0014 18.4 0.7 1.2 8.9 0.3 2.4 2 0 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 KUM64502.1 - 0.0016 18.4 0.1 0.87 9.6 0.0 2.7 3 0 0 3 3 3 1 TrkA-N domain Lycopene_cycl PF05834.7 KUM64502.1 - 0.0037 16.2 0.0 0.32 9.8 0.0 2.9 4 0 0 4 4 4 1 Lycopene cyclase protein NAD_binding_7 PF13241.1 KUM64502.1 - 0.0048 17.1 0.0 0.24 11.6 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.9 KUM64502.1 - 0.0053 15.2 0.0 0.38 9.1 0.0 2.5 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.19 KUM64502.1 - 0.017 14.0 0.5 5.1 5.8 0.0 3.0 3 1 0 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.17 KUM64502.1 - 0.024 13.5 0.1 6.7 5.4 0.0 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A ELFV_dehydrog PF00208.16 KUM64502.1 - 0.035 13.6 1.1 0.055 13.0 0.4 1.5 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Shikimate_DH PF01488.15 KUM64502.1 - 0.04 14.0 0.0 3.3 7.8 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 KUM64502.1 - 0.073 13.4 0.0 11 6.4 0.0 3.1 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 KUM64502.1 - 0.085 12.2 0.0 16 4.9 0.0 2.6 2 1 1 3 3 3 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 KUM64502.1 - 0.12 11.4 0.0 15 4.6 0.0 2.7 3 0 0 3 3 3 0 Thi4 family APH PF01636.18 KUM64503.1 - 4.7e-16 59.2 0.0 5.5e-15 55.7 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KUM64503.1 - 0.00059 19.4 0.0 0.0015 18.1 0.0 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase HNH_2 PF13391.1 KUM64503.1 - 0.021 14.5 0.0 0.11 12.2 0.0 2.3 2 0 0 2 2 2 0 HNH endonuclease Transferase PF02458.10 KUM64505.1 - 0.0021 16.5 0.0 0.56 8.5 0.0 2.1 2 0 0 2 2 2 2 Transferase family GFO_IDH_MocA PF01408.17 KUM64506.1 - 8.3e-14 52.1 0.0 1.4e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CLASP_N PF12348.3 KUM64508.1 - 1.1e-144 479.6 0.0 2.1e-84 282.4 0.0 2.3 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.17 KUM64508.1 - 1.9e-09 36.7 0.1 0.038 14.0 0.0 5.8 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.2 KUM64508.1 - 7.2e-07 29.2 0.3 0.0012 18.7 0.0 3.3 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KUM64508.1 - 2e-06 27.9 0.6 0.65 10.3 0.0 4.7 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 KUM64508.1 - 0.00011 22.5 0.1 1.5 9.4 0.0 4.5 5 0 0 5 5 5 2 HEAT-like repeat Condensin2nSMC PF12422.3 KUM64508.1 - 0.041 13.6 0.0 8.1 6.1 0.0 3.4 5 0 0 5 5 5 0 Condensin II non structural maintenance of chromosomes subunit SURF4 PF02077.10 KUM64510.1 - 1.9e-94 316.0 7.7 2.1e-94 315.8 5.4 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.7 KUM64510.1 - 0.27 11.6 17.6 0.16 12.4 2.6 3.0 3 2 0 3 3 3 0 DoxX DUF3021 PF11457.3 KUM64510.1 - 0.4 10.5 10.0 0.75 9.6 6.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3021) LSM PF01423.17 KUM64512.1 - 1.7e-14 53.0 0.1 2.4e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 LSM domain Bd3614-deam PF14439.1 KUM64513.1 - 0.04 13.7 1.8 0.054 13.3 1.2 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase SLX9 PF15341.1 KUM64514.1 - 0.00028 21.3 2.5 3.4 8.1 1.7 3.8 1 1 0 1 1 1 1 Ribosome biogenesis protein SLX9 C8 PF08742.6 KUM64514.1 - 0.0099 16.1 0.9 0.018 15.3 0.6 1.3 1 0 0 1 1 1 1 C8 domain DUF4414 PF14377.1 KUM64516.1 - 0.19 11.6 0.0 0.19 11.6 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4414) CDC45 PF02724.9 KUM64516.1 - 3.6 5.5 10.0 5.5 4.8 7.0 1.2 1 0 0 1 1 1 0 CDC45-like protein ADH_N PF08240.7 KUM64518.1 - 2.6e-26 91.5 0.7 4.6e-26 90.6 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM64518.1 - 1.2e-20 73.3 0.4 1.8e-20 72.7 0.3 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KUM64518.1 - 0.016 16.0 0.1 0.032 15.1 0.1 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PI3_PI4_kinase PF00454.22 KUM64519.1 - 2.5e-45 154.7 0.0 5.6e-45 153.6 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KUM64519.1 - 2.2e-10 39.7 0.1 5.6e-10 38.4 0.1 1.7 1 0 0 1 1 1 1 FATC domain DUF4015 PF13200.1 KUM64519.1 - 0.065 12.1 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain DUF1353 PF07087.6 KUM64519.1 - 0.09 12.2 0.1 0.45 10.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1353) APH PF01636.18 KUM64520.1 - 1e-09 38.5 0.3 9.1e-09 35.3 0.2 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KUM64520.1 - 0.048 12.6 0.0 0.091 11.7 0.0 1.4 1 0 0 1 1 1 0 Fructosamine kinase DUF3414 PF11894.3 KUM64521.1 - 0 1479.0 13.8 0 1478.7 9.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) TAN PF11640.3 KUM64522.1 - 1.2e-52 177.7 0.3 4.9e-52 175.7 0.1 2.0 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair Fungal_trans_2 PF11951.3 KUM64523.1 - 0.00025 19.7 0.5 0.0026 16.4 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain MFS_1 PF07690.11 KUM64528.1 - 1.4e-47 162.1 30.7 1.4e-47 162.1 21.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM64528.1 - 1.2e-11 43.8 4.9 1.2e-11 43.8 3.4 3.2 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM64529.1 - 7.1e-20 71.0 57.9 3.1e-16 59.0 22.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KUM64529.1 - 0.037 12.2 14.0 0.0064 14.7 6.9 1.6 1 1 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Phospho_p8 PF10195.4 KUM64530.1 - 0.077 12.8 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 DNA-binding nuclear phosphoprotein p8 HhH-GPD PF00730.20 KUM64531.1 - 3.9e-06 27.1 0.0 9.5e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein G_glu_transpept PF01019.16 KUM64532.1 - 3.3e-160 533.9 0.0 3.8e-160 533.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase SET PF00856.23 KUM64533.1 - 9.2e-09 35.8 0.0 1e-05 25.8 0.0 2.6 2 0 0 2 2 2 2 SET domain TPR_11 PF13414.1 KUM64533.1 - 6.8e-08 32.0 0.3 1.4e-07 31.0 0.2 1.5 1 0 0 1 1 1 1 TPR repeat SAP PF02037.22 KUM64533.1 - 0.00065 19.1 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 SAP domain TPR_17 PF13431.1 KUM64533.1 - 0.00087 19.3 0.1 0.0025 17.8 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 KUM64533.1 - 0.0016 19.0 0.0 0.0037 17.9 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 KUM64533.1 - 0.012 15.1 0.4 0.81 9.4 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KUM64533.1 - 0.054 13.4 0.3 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat PriCT_1 PF08708.6 KUM64534.1 - 0.028 14.2 0.0 0.086 12.6 0.0 1.8 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) HA PF03457.9 KUM64534.1 - 0.039 14.0 0.5 0.12 12.5 0.4 1.7 1 0 0 1 1 1 0 Helicase associated domain RhoGAP PF00620.22 KUM64535.1 - 8.9e-28 96.8 0.0 1.5e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain RRS1 PF04939.7 KUM64536.1 - 7.4e-59 197.8 4.0 8.9e-59 197.6 2.8 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) DAP3 PF10236.4 KUM64537.1 - 6.7e-97 324.1 0.0 8.1e-97 323.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 T2SE PF00437.15 KUM64537.1 - 0.057 12.3 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Aldo_ket_red PF00248.16 KUM64538.1 - 1.1e-63 214.7 0.0 1.3e-63 214.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Claudin_3 PF06653.6 KUM64538.1 - 0.051 13.2 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like Prenyltrans PF00432.16 KUM64541.1 - 7.9e-55 182.0 6.9 1.7e-11 43.4 0.1 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KUM64541.1 - 4.3e-39 133.4 0.5 4e-13 49.7 0.0 3.9 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KUM64541.1 - 1.7e-12 47.2 0.0 0.00038 20.4 0.0 3.8 2 1 1 3 3 3 2 Prenyltransferase-like OPT PF03169.10 KUM64542.1 - 5.8e-148 494.0 51.6 3.1e-145 485.0 30.6 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein Abhydrolase_5 PF12695.2 KUM64543.1 - 9.8e-22 77.2 0.0 1.6e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KUM64543.1 - 2.5e-18 66.8 0.0 4.4e-17 62.7 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KUM64543.1 - 1.2e-06 27.9 0.0 3.5e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.8 KUM64543.1 - 3.9e-05 23.1 0.0 0.00019 20.9 0.0 2.0 2 1 0 2 2 2 1 Serine hydrolase (FSH1) AXE1 PF05448.7 KUM64543.1 - 0.0001 20.9 0.1 0.28 9.6 0.0 2.5 2 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 KUM64543.1 - 0.00023 20.7 0.0 0.016 14.7 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.6 KUM64543.1 - 0.00083 19.1 0.0 0.11 12.1 0.0 2.4 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF818 PF05677.7 KUM64543.1 - 0.00091 18.0 0.0 0.0013 17.5 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.11 KUM64543.1 - 0.0027 17.2 0.0 0.39 10.1 0.0 2.2 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase PGAP1 PF07819.8 KUM64543.1 - 0.0038 16.8 0.0 0.017 14.6 0.0 2.1 1 1 0 1 1 1 1 PGAP1-like protein DLH PF01738.13 KUM64543.1 - 0.0057 15.9 0.0 0.51 9.5 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 KUM64543.1 - 0.0093 15.5 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 KUM64543.1 - 0.0096 15.3 0.0 0.04 13.3 0.0 1.8 2 0 0 2 2 2 1 Putative esterase Lipase_3 PF01764.20 KUM64543.1 - 0.022 14.3 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) ATP11 PF06644.6 KUM64544.1 - 2.2e-86 289.6 0.0 2.5e-86 289.4 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein DUF1880 PF08976.6 KUM64544.1 - 0.018 15.1 0.3 0.034 14.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1880) zf-C4H2 PF10146.4 KUM64544.1 - 0.054 13.5 4.7 0.045 13.7 1.9 1.6 1 1 1 2 2 2 0 Zinc finger-containing protein Cyclin PF08613.6 KUM64545.1 - 6.3e-38 130.5 1.0 2.5e-22 79.9 0.3 2.5 2 0 0 2 2 2 2 Cyclin Proteasome PF00227.21 KUM64546.1 - 4.3e-47 159.8 0.2 5e-47 159.6 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Evr1_Alr PF04777.8 KUM64547.1 - 1.3e-27 95.5 0.1 1.9e-27 95.0 0.1 1.2 1 0 0 1 1 1 1 Erv1 / Alr family Pox_E10 PF04805.7 KUM64547.1 - 0.11 12.0 0.0 0.46 10.0 0.0 1.9 2 0 0 2 2 2 0 E10-like protein conserved region Glyco_hydro_92 PF07971.7 KUM64548.1 - 1e-171 572.0 0.1 1.3e-171 571.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 R3H PF01424.17 KUM64549.1 - 1.4e-10 40.6 0.0 3.1e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 R3H domain Rpp20 PF12328.3 KUM64549.1 - 1.8 8.2 6.0 0.18 11.4 0.8 1.7 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P Abhydrolase_6 PF12697.2 KUM64553.1 - 2.4e-22 79.9 0.0 2.9e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM64553.1 - 1e-16 61.1 0.0 4.5e-15 55.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KUM64553.1 - 6.9e-09 35.5 0.0 1.6e-08 34.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KUM64553.1 - 3.8e-06 25.5 0.0 8.5e-06 24.4 0.0 1.5 1 1 0 1 1 1 1 Ndr family PhoPQ_related PF10142.4 KUM64553.1 - 0.013 14.0 0.0 0.03 12.8 0.0 1.5 2 0 0 2 2 2 0 PhoPQ-activated pathogenicity-related protein Abhydrolase_3 PF07859.8 KUM64553.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1857 PF08982.6 KUM64554.1 - 7.2e-39 132.7 0.0 8.1e-39 132.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Lipocalin PF00061.18 KUM64554.1 - 0.062 13.2 0.1 0.11 12.5 0.0 1.3 1 1 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family PhzC-PhzF PF02567.11 KUM64555.1 - 2.8e-49 167.8 0.0 3.6e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein adh_short PF00106.20 KUM64556.1 - 1.9e-21 76.6 0.0 2.1e-20 73.3 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KUM64556.1 - 3.2e-11 43.2 0.0 5.3e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KUM64556.1 - 2.2e-09 37.4 0.0 4.9e-07 29.7 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KUM64556.1 - 0.0045 17.0 0.0 0.013 15.4 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KUM64556.1 - 0.033 13.0 0.0 0.046 12.6 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF706 PF05153.10 KUM64557.1 - 9e-119 395.4 7.6 3.9e-116 386.7 1.3 2.1 1 1 1 2 2 2 2 Family of unknown function (DUF706) HD PF01966.17 KUM64557.1 - 0.026 14.5 0.3 0.3 11.1 0.0 2.5 2 1 1 3 3 3 0 HD domain IBR PF01485.16 KUM64558.1 - 1.1e-11 44.4 36.6 2.3e-06 27.4 4.1 3.4 3 0 0 3 3 3 3 IBR domain zf-RING_5 PF14634.1 KUM64558.1 - 0.002 17.8 7.1 0.002 17.8 4.9 3.8 3 1 0 3 3 3 2 zinc-RING finger domain zf-RING_2 PF13639.1 KUM64558.1 - 0.0047 16.7 6.8 0.0047 16.7 4.7 4.3 3 1 1 4 4 4 2 Ring finger domain zf-C3HC4 PF00097.20 KUM64558.1 - 0.011 15.4 6.7 0.011 15.4 4.7 4.1 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Actin PF00022.14 KUM64559.1 - 2.5e-106 355.4 0.0 3.2e-106 355.0 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KUM64559.1 - 0.08 11.5 0.0 0.19 10.2 0.0 1.6 2 0 0 2 2 2 0 MreB/Mbl protein TIMELESS PF04821.9 KUM64560.1 - 2.6e-95 318.7 0.1 7.3e-95 317.2 0.1 1.8 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.8 KUM64560.1 - 9.3e-63 213.0 30.3 4.3e-60 204.2 0.3 4.2 2 1 1 3 3 3 2 Timeless protein C terminal region 3HCDH_N PF02737.13 KUM64561.1 - 8.1e-52 175.4 2.0 1.1e-51 175.0 1.4 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KUM64561.1 - 4.2e-33 113.6 0.1 1.2e-32 112.1 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KUM64561.1 - 0.00034 20.4 0.8 0.00064 19.6 0.2 1.7 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 KUM64561.1 - 0.0009 18.9 0.3 0.0015 18.2 0.2 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 KUM64561.1 - 0.0014 17.6 0.2 0.0017 17.3 0.2 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase ApbA PF02558.11 KUM64561.1 - 0.005 16.2 0.2 0.017 14.5 0.1 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA DAO PF01266.19 KUM64561.1 - 0.0065 15.4 0.1 0.0065 15.4 0.1 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.13 KUM64561.1 - 0.014 15.3 0.6 0.036 14.0 0.2 2.0 2 1 0 2 2 2 0 TrkA-N domain TfuA PF07812.7 KUM64561.1 - 0.024 14.0 0.1 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 TfuA-like protein F420_oxidored PF03807.12 KUM64561.1 - 0.024 15.0 1.7 0.08 13.3 0.6 2.4 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 KUM64561.1 - 0.035 13.2 0.5 0.16 11.0 0.3 2.1 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 KUM64561.1 - 0.071 13.1 0.6 0.29 11.1 0.3 1.9 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KUM64561.1 - 0.1 12.4 0.1 0.16 11.8 0.1 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_S64 PF08192.6 KUM64562.1 - 3.3e-05 22.4 0.0 6.5e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S64 Peptidase_S32 PF05579.8 KUM64562.1 - 0.1 11.5 2.4 0.082 11.8 0.5 1.6 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 NmrA PF05368.8 KUM64564.1 - 2.1e-20 72.9 0.0 2.8e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KUM64564.1 - 3.6e-12 46.6 0.1 1.2e-11 44.9 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KUM64564.1 - 4.3e-08 32.8 0.1 4e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KUM64564.1 - 0.00037 19.4 0.0 0.00053 18.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Saccharop_dh PF03435.13 KUM64564.1 - 0.0017 17.3 0.2 0.0028 16.6 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 KUM64564.1 - 0.0019 18.1 0.1 0.0034 17.3 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 KUM64564.1 - 0.0034 16.1 0.2 0.0051 15.5 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KUM64564.1 - 0.018 14.7 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.10 KUM64564.1 - 0.036 12.9 0.2 0.055 12.3 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TcdB_toxin_midN PF12256.3 KUM64564.1 - 0.092 12.1 0.1 0.33 10.3 0.0 2.0 3 0 0 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region TrkA_N PF02254.13 KUM64564.1 - 0.1 12.6 0.1 0.27 11.2 0.1 1.7 2 0 0 2 2 2 0 TrkA-N domain DUF3842 PF12953.2 KUM64564.1 - 0.11 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) eIF-3c_N PF05470.7 KUM64566.1 - 6.4e-164 546.3 21.2 6.4e-164 546.3 14.7 2.4 2 1 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 KUM64566.1 - 2e-12 47.3 1.8 1.2e-11 44.8 0.0 3.1 2 1 1 3 3 3 1 PCI domain Pkinase PF00069.20 KUM64567.1 - 1.9e-50 171.4 0.0 4.5e-50 170.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM64567.1 - 3.4e-21 75.4 0.0 7e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KUM64567.1 - 0.00081 19.1 0.7 0.0014 18.3 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KUM64567.1 - 0.0086 15.4 0.4 0.062 12.6 0.0 2.1 1 1 1 2 2 2 1 RIO1 family Fungal_trans PF04082.13 KUM64569.1 - 1.6e-18 66.5 0.0 2.6e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM64569.1 - 3.8e-08 33.0 10.8 7.4e-08 32.1 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LysM PF01476.15 KUM64570.1 - 4.9e-07 29.5 0.1 8.6e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 LysM domain DUP PF00674.13 KUM64570.1 - 0.096 12.6 0.1 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 DUP family cNMP_binding PF00027.24 KUM64571.1 - 3.2e-40 135.8 0.2 2.8e-21 75.1 0.0 5.2 5 1 0 5 5 5 3 Cyclic nucleotide-binding domain Patatin PF01734.17 KUM64571.1 - 2.7e-18 66.6 5.7 6.4e-17 62.1 4.0 2.8 1 1 0 1 1 1 1 Patatin-like phospholipase MARVEL PF01284.18 KUM64572.1 - 2.7e-15 56.4 9.1 3.7e-15 56.0 6.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF1774 PF08611.5 KUM64572.1 - 0.001 19.2 1.2 0.088 12.9 0.0 2.4 2 0 0 2 2 2 2 Fungal protein of unknown function (DUF1774) DUF2615 PF11027.3 KUM64572.1 - 0.026 14.4 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) DUF872 PF05915.7 KUM64572.1 - 0.095 12.5 0.1 15 5.5 0.1 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) CEP19 PF14933.1 KUM64573.1 - 1.1 9.5 5.9 0.35 11.1 1.3 2.0 2 0 0 2 2 2 0 CEP19-like protein Ribosomal_L13e PF01294.13 KUM64574.1 - 5.4e-64 214.9 9.0 1.2e-63 213.8 6.0 1.7 1 1 0 1 1 1 1 Ribosomal protein L13e FAM60A PF15396.1 KUM64574.1 - 0.025 14.3 0.2 0.025 14.3 0.1 1.6 2 0 0 2 2 2 0 Protein Family FAM60A Poty_PP PF08440.5 KUM64574.1 - 0.089 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Potyviridae polyprotein Oxidored-like PF09791.4 KUM64576.1 - 3.1e-25 87.3 2.7 3.1e-25 87.3 1.9 1.7 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal ABC2_membrane PF01061.19 KUM64578.1 - 2.2e-87 291.6 48.0 1.9e-46 157.8 12.4 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KUM64578.1 - 5.7e-39 133.5 0.0 8.6e-19 68.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KUM64578.1 - 2.8e-26 91.1 0.0 1.4e-22 79.2 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 KUM64578.1 - 2.7e-14 52.9 29.0 4e-08 32.6 8.2 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 KUM64578.1 - 1e-09 38.3 0.1 2.4e-09 37.1 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 KUM64578.1 - 4.2e-05 22.8 0.1 0.0041 16.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KUM64578.1 - 0.00013 21.4 0.2 0.013 14.8 0.1 2.7 2 1 0 2 2 2 1 AAA domain cobW PF02492.14 KUM64578.1 - 0.00016 21.1 1.1 0.36 10.2 0.2 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 KUM64578.1 - 0.00025 21.2 0.1 0.12 12.4 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KUM64578.1 - 0.00083 19.4 0.1 1.2 9.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KUM64578.1 - 0.00084 19.3 0.7 0.11 12.4 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KUM64578.1 - 0.00085 18.7 0.4 0.077 12.5 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 KUM64578.1 - 0.0023 18.2 0.0 1.2 9.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KUM64578.1 - 0.0029 17.4 0.0 1.5 8.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.1 KUM64578.1 - 0.003 17.5 0.5 0.37 10.7 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KUM64578.1 - 0.0088 15.7 0.5 3.2 7.5 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain Arch_ATPase PF01637.13 KUM64578.1 - 0.0098 15.6 0.0 4 7.0 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase PduV-EutP PF10662.4 KUM64578.1 - 0.018 14.5 0.2 1.5 8.3 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 KUM64578.1 - 0.031 14.2 0.0 3.9 7.4 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.1 KUM64578.1 - 0.034 14.9 0.0 0.94 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KUM64578.1 - 0.12 12.0 0.5 4.6 6.8 0.2 2.3 2 0 0 2 2 2 0 NACHT domain SMC_N PF02463.14 KUM64578.1 - 0.12 11.5 0.0 0.91 8.7 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.13 KUM64578.1 - 0.28 10.6 0.3 5.5 6.3 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family GCIP PF13324.1 KUM64579.1 - 8.4e-09 35.0 0.5 2.6e-08 33.4 0.0 1.8 1 1 1 2 2 2 1 Grap2 and cyclin-D-interacting bZIP_1 PF00170.16 KUM64579.1 - 0.00026 20.8 1.7 0.00061 19.7 1.2 1.6 1 0 0 1 1 1 1 bZIP transcription factor DUF585 PF04522.7 KUM64579.1 - 0.37 10.1 5.9 0.73 9.1 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF585) Sigma70_ner PF04546.8 KUM64579.1 - 2.1 7.8 9.7 0.039 13.5 1.0 2.3 3 0 0 3 3 3 0 Sigma-70, non-essential region LRR_4 PF12799.2 KUM64580.1 - 2.2e-43 145.2 41.6 4.5e-10 38.9 0.4 10.7 6 3 3 11 11 11 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KUM64580.1 - 1.6e-28 98.2 46.1 1.3e-08 34.4 2.0 8.7 5 2 6 11 11 11 9 Leucine rich repeat LRR_1 PF00560.28 KUM64580.1 - 1.5e-18 63.9 40.5 0.035 14.1 0.1 15.5 15 2 1 16 16 16 7 Leucine Rich Repeat LRR_7 PF13504.1 KUM64580.1 - 3.4e-17 59.5 42.6 0.11 12.7 0.1 14.5 14 1 0 14 14 14 6 Leucine rich repeat LRR_6 PF13516.1 KUM64580.1 - 2.9e-11 42.2 32.0 3.9 7.8 2.3 12.7 13 0 0 13 13 13 5 Leucine Rich repeat LRR_9 PF14580.1 KUM64580.1 - 0.31 10.5 13.7 8.3 5.9 1.6 4.5 2 1 3 5 5 5 0 Leucine-rich repeat CoA_transf_3 PF02515.12 KUM64581.1 - 4.8e-29 100.9 0.0 8.4e-29 100.1 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III DUF3245 PF11595.3 KUM64583.1 - 2.9e-47 160.6 8.6 2.9e-47 160.6 5.9 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3245) Ribosomal_60s PF00428.14 KUM64583.1 - 0.0092 16.3 11.9 0.0092 16.3 8.3 3.2 2 1 1 3 3 3 1 60s Acidic ribosomal protein Cpl-7 PF08230.6 KUM64583.1 - 0.1 12.3 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Cpl-7 lysozyme C-terminal domain MRI PF15325.1 KUM64583.1 - 3.3 8.7 12.0 3.2 8.7 1.5 3.1 2 1 1 3 3 3 0 Modulator of retrovirus infection Spore_YtfJ PF09579.5 KUM64583.1 - 4.7 7.1 5.5 0.69 9.8 0.8 1.9 1 1 1 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) p450 PF00067.17 KUM64584.1 - 1.4e-68 231.5 0.0 1.8e-68 231.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HA2 PF04408.18 KUM64585.1 - 7.2e-14 51.6 0.0 1.5e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Med27 PF11571.3 KUM64586.1 - 6e-18 64.7 0.0 1.1e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 27 2OG-FeII_Oxy_3 PF13640.1 KUM64589.1 - 3.4e-07 30.6 0.1 7.5e-05 23.1 0.1 2.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KUM64589.1 - 0.049 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 KUM64590.1 - 1.7e-23 82.8 84.2 5.7e-21 74.6 33.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily 2OG-FeII_Oxy PF03171.15 KUM64591.1 - 5.9e-12 45.7 0.0 1.1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TALPID3 PF15324.1 KUM64591.1 - 0.099 9.9 0.9 0.11 9.8 0.7 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Suc_Fer-like PF06999.7 KUM64592.1 - 1.4e-46 159.4 0.0 1.6e-46 159.1 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like PHA_gran_rgn PF09650.5 KUM64593.1 - 0.15 12.2 0.6 1.3 9.1 0.4 2.1 1 1 0 1 1 1 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) SNF2_N PF00176.18 KUM64595.1 - 2.6e-71 239.8 0.0 4.2e-71 239.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KUM64595.1 - 2.8e-14 52.7 0.0 8.6e-14 51.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KUM64595.1 - 0.016 14.7 0.0 0.16 11.4 0.0 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase GRIP PF01465.15 KUM64596.1 - 3.8e-19 67.9 0.2 7.9e-19 66.9 0.1 1.6 1 0 0 1 1 1 1 GRIP domain IncA PF04156.9 KUM64596.1 - 1.2e-10 41.3 144.0 0.002 17.7 9.9 9.4 2 2 6 8 8 8 5 IncA protein CENP-F_leu_zip PF10473.4 KUM64596.1 - 4.1e-09 36.4 154.9 1.7e-05 24.6 8.5 11.0 3 2 5 9 9 9 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.6 KUM64596.1 - 5.7e-07 28.5 123.5 0.0022 16.7 11.7 7.6 2 2 4 7 7 7 6 Spc7 kinetochore protein DUF3584 PF12128.3 KUM64596.1 - 9.6e-06 23.2 41.3 9.6e-06 23.2 28.6 6.0 1 1 3 5 5 5 2 Protein of unknown function (DUF3584) AAA_13 PF13166.1 KUM64596.1 - 4.1e-05 22.2 105.2 0.024 13.1 14.4 5.3 1 1 3 5 5 5 3 AAA domain Reo_sigmaC PF04582.7 KUM64596.1 - 7.2e-05 22.1 57.7 0.095 11.8 3.8 7.0 3 2 4 8 8 8 4 Reovirus sigma C capsid protein FliJ PF02050.11 KUM64596.1 - 7.2e-05 22.8 92.9 0.0068 16.4 0.7 9.8 4 2 8 13 13 13 5 Flagellar FliJ protein GAS PF13851.1 KUM64596.1 - 0.00025 20.3 130.4 0.026 13.7 9.7 9.1 2 2 6 8 8 8 2 Growth-arrest specific micro-tubule binding DUF869 PF05911.6 KUM64596.1 - 0.00095 17.5 119.5 0.24 9.5 9.7 5.9 1 1 5 6 6 6 3 Plant protein of unknown function (DUF869) Cast PF10174.4 KUM64596.1 - 0.0015 16.6 40.2 0.0015 16.6 27.9 5.5 2 1 2 4 4 3 2 RIM-binding protein of the cytomatrix active zone ALIX_LYPXL_bnd PF13949.1 KUM64596.1 - 0.0024 16.8 23.3 0.0024 16.8 16.1 6.0 3 1 1 4 4 2 1 ALIX V-shaped domain binding to HIV DivIC PF04977.10 KUM64596.1 - 0.0045 16.4 0.8 0.0045 16.4 0.5 14.8 7 5 8 17 17 17 3 Septum formation initiator Filament PF00038.16 KUM64596.1 - 0.0049 16.3 121.8 0.068 12.6 24.8 8.1 2 2 4 6 6 6 5 Intermediate filament protein DUF4201 PF13870.1 KUM64596.1 - 0.0057 16.1 5.6 0.0057 16.1 3.9 9.7 2 2 6 9 9 9 5 Domain of unknown function (DUF4201) EzrA PF06160.7 KUM64596.1 - 0.0062 14.7 102.5 0.022 12.9 7.7 6.5 2 2 2 6 6 6 4 Septation ring formation regulator, EzrA MscS_porin PF12795.2 KUM64596.1 - 0.011 15.0 123.1 0.086 12.1 5.2 8.2 4 2 2 7 7 7 0 Mechanosensitive ion channel porin domain Snapin_Pallidin PF14712.1 KUM64596.1 - 0.013 15.7 3.3 0.013 15.7 2.3 10.4 6 3 3 10 10 10 0 Snapin/Pallidin Fib_alpha PF08702.5 KUM64596.1 - 0.15 12.1 87.0 1.1 9.4 5.7 8.7 3 2 6 9 9 8 0 Fibrinogen alpha/beta chain family AAA_27 PF13514.1 KUM64596.1 - 0.17 9.4 120.0 0.061 11.0 21.8 3.7 2 1 0 2 2 2 0 AAA domain WEMBL PF05701.6 KUM64596.1 - 0.19 10.1 146.2 0.43 8.9 13.0 5.9 2 2 3 5 5 5 0 Weak chloroplast movement under blue light Bacillus_HBL PF05791.6 KUM64596.1 - 0.22 10.8 79.5 0.018 14.4 3.3 9.2 5 3 4 9 9 9 0 Bacillus haemolytic enterotoxin (HBL) TPR_MLP1_2 PF07926.7 KUM64596.1 - 1.4 8.6 139.0 0.043 13.5 4.2 10.4 3 1 7 11 11 8 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.6 KUM64596.1 - 1.9 8.2 136.2 1.2 8.8 10.9 9.1 3 2 5 8 8 8 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.7 KUM64596.1 - 2.5 8.4 56.7 5.7 7.2 0.3 10.5 4 4 1 6 6 4 0 Nucleopolyhedrovirus P10 protein APG6 PF04111.7 KUM64596.1 - 2.6 6.9 138.2 0.0077 15.3 11.3 8.0 2 2 7 9 9 9 0 Autophagy protein Apg6 TBPIP PF07106.8 KUM64596.1 - 5.5 6.5 116.8 0.24 10.9 3.6 10.4 3 3 7 11 11 11 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Pet191_N PF10203.4 KUM64597.1 - 0.022 14.7 0.2 0.031 14.3 0.2 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Abhydro_lipase PF04083.11 KUM64598.1 - 5.3e-22 76.9 0.3 1.2e-21 75.8 0.0 1.8 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 KUM64598.1 - 3.9e-18 65.8 0.2 6.2e-18 65.2 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KUM64598.1 - 2e-07 31.1 0.0 3.2e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM64598.1 - 2.7e-05 23.9 0.0 0.00018 21.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KUM64598.1 - 0.0023 17.4 0.0 0.46 9.8 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Tannase PF07519.6 KUM64599.1 - 2.2e-145 485.0 4.1 2.7e-145 484.7 2.8 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase adh_short_C2 PF13561.1 KUM64600.1 - 2.9e-12 46.8 0.0 3.2e-12 46.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase EAP30 PF04157.11 KUM64600.1 - 0.0069 15.5 0.0 0.0082 15.3 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family adh_short PF00106.20 KUM64601.1 - 6.2e-24 84.7 0.8 7.6e-24 84.5 0.5 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM64601.1 - 4.1e-13 49.3 0.5 5.5e-13 48.9 0.4 1.0 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KUM64601.1 - 1.1e-11 44.9 0.1 1.3e-11 44.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 KUM64601.1 - 0.0043 16.7 0.5 0.0095 15.6 0.3 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SBP_bac_3 PF00497.15 KUM64601.1 - 0.046 12.9 0.4 0.66 9.1 0.3 2.0 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 DUF3367 PF11847.3 KUM64601.1 - 0.1 10.5 0.0 0.11 10.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) SNF2_N PF00176.18 KUM64602.1 - 7.7e-85 284.2 1.2 7.7e-85 284.2 0.8 2.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 KUM64602.1 - 7.9e-24 83.3 0.2 2.5e-23 81.7 0.1 1.9 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 KUM64602.1 - 3.1e-18 65.4 2.4 2e-17 62.7 0.0 3.5 4 0 0 4 4 4 1 Helicase conserved C-terminal domain SnAC PF14619.1 KUM64602.1 - 7.9e-18 64.4 3.1 7.9e-18 64.4 2.2 4.3 4 1 1 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 KUM64602.1 - 7.8e-17 60.8 13.6 7.8e-17 60.8 9.4 2.8 2 0 0 2 2 2 1 HSA QLQ PF08880.6 KUM64602.1 - 2.1e-13 49.4 1.3 8.3e-13 47.5 0.9 2.2 1 0 0 1 1 1 1 QLQ M11L PF11099.3 KUM64602.1 - 0.049 13.3 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 Apoptosis regulator M11L like BAR PF03114.13 KUM64603.1 - 2e-47 161.6 5.6 2.6e-47 161.2 3.9 1.2 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 KUM64603.1 - 4.5e-06 25.7 2.9 6e-06 25.3 2.0 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking APG6 PF04111.7 KUM64603.1 - 5.8 5.8 10.6 9.8 5.1 7.4 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Spo12 PF05032.7 KUM64604.1 - 7.9e-17 60.5 1.4 1.6e-16 59.6 1.0 1.5 1 0 0 1 1 1 1 Spo12 family Acyl-CoA_dh_1 PF00441.19 KUM64605.1 - 1.9e-29 102.7 1.5 3e-29 102.0 1.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KUM64605.1 - 1.9e-16 59.2 0.3 5.3e-16 57.8 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KUM64605.1 - 5.8e-15 55.7 2.9 9.8e-15 54.9 2.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KUM64605.1 - 3.6e-13 50.0 0.1 7.4e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Ribosomal_L5_C PF00673.16 KUM64606.1 - 1.1e-25 89.2 0.0 1.7e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus UCH_1 PF13423.1 KUM64607.1 - 1.1e-73 248.3 0.4 1.1e-72 245.0 0.0 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ndc1_Nup PF09531.5 KUM64607.1 - 0.25 9.7 0.6 0.43 8.9 0.4 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pkinase PF00069.20 KUM64609.1 - 1.7e-67 227.3 0.0 3.1e-67 226.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM64609.1 - 8.7e-49 165.9 0.0 3.7e-48 163.8 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 KUM64609.1 - 2.3e-30 104.6 0.0 5e-30 103.5 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 KUM64609.1 - 3.4e-16 59.1 0.0 8.1e-16 57.9 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KUM64609.1 - 6e-14 51.6 0.1 2.6e-13 49.6 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 KUM64609.1 - 4.3e-07 29.1 0.0 0.00031 19.8 0.0 2.4 2 0 0 2 2 2 2 Kinase-like RA PF00788.18 KUM64609.1 - 6.6e-06 26.5 0.0 1.3e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kdo PF06293.9 KUM64609.1 - 0.017 14.2 0.0 0.034 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KUM64610.1 - 8.5e-57 192.2 0.0 1.2e-56 191.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM64610.1 - 2.1e-34 118.7 0.0 2.8e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM64610.1 - 7.8e-12 44.7 0.0 6.5e-08 31.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Cas_APE2256 PF09651.5 KUM64610.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) Kdo PF06293.9 KUM64610.1 - 0.15 11.1 0.0 0.33 9.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sad1_UNC PF07738.8 KUM64611.1 - 5.5e-33 113.6 0.1 9.8e-33 112.8 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Pep3_Vps18 PF05131.9 KUM64612.1 - 9.6e-45 151.6 0.1 4.1e-44 149.5 0.0 2.1 3 0 0 3 3 3 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 KUM64612.1 - 5.7e-08 32.4 2.9 0.00023 20.8 0.0 3.8 3 1 2 5 5 5 3 Region in Clathrin and VPS zf-RING_2 PF13639.1 KUM64612.1 - 0.00082 19.1 0.5 0.0019 18.0 0.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KUM64612.1 - 0.0013 18.3 0.2 0.0032 17.1 0.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KUM64612.1 - 0.065 12.8 0.1 0.19 11.4 0.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2175 PF09943.4 KUM64612.1 - 0.12 12.4 0.1 0.37 10.8 0.1 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) zf-C3HC4_2 PF13923.1 KUM64612.1 - 0.34 10.9 0.9 0.78 9.8 0.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_clus PF00172.13 KUM64613.1 - 2.2e-10 40.2 10.2 4.2e-10 39.3 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KUM64613.1 - 8.6e-09 34.6 0.7 2e-08 33.4 0.5 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ada_Zn_binding PF02805.11 KUM64614.1 - 7.9e-28 95.8 4.6 1.3e-27 95.1 3.2 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 KUM64614.1 - 1.5e-09 37.3 0.0 3.1e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 KUM64614.1 - 2.6e-05 24.2 0.0 5.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain TetR_N PF00440.18 KUM64614.1 - 0.12 12.0 0.0 0.33 10.6 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family SNF2_N PF00176.18 KUM64617.1 - 1.4e-70 237.4 0.0 2e-70 236.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 KUM64617.1 - 5.9e-14 51.8 0.0 1.3e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 KUM64617.1 - 1.8e-12 46.9 0.0 4e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 KUM64617.1 - 1.9e-10 40.3 9.7 4.1e-10 39.3 6.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KUM64617.1 - 1e-09 37.8 8.6 1e-09 37.8 5.9 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KUM64617.1 - 2.1e-09 37.2 10.3 2.1e-09 37.2 7.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KUM64617.1 - 4.1e-09 35.9 10.7 4.1e-09 35.9 7.4 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KUM64617.1 - 3.1e-07 30.1 9.7 5.8e-07 29.2 6.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KUM64617.1 - 3.4e-07 29.8 8.9 7.3e-07 28.8 6.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KUM64617.1 - 4.4e-05 23.5 4.1 0.00013 22.0 2.9 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Nse PF11789.3 KUM64617.1 - 0.0011 18.4 5.8 0.0026 17.2 4.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 KUM64617.1 - 0.0019 17.8 5.8 0.0055 16.3 4.0 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 KUM64617.1 - 0.022 14.5 3.8 0.049 13.4 2.6 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 KUM64617.1 - 0.066 12.7 3.4 0.14 11.7 2.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 U-box PF04564.10 KUM64617.1 - 0.09 12.7 0.2 0.47 10.4 0.0 2.3 3 0 0 3 3 2 0 U-box domain zf-RING_4 PF14570.1 KUM64617.1 - 0.11 12.1 7.4 0.26 10.9 5.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Ribonuc_L-PSP PF01042.16 KUM64618.1 - 2.5e-23 82.1 0.0 3.1e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP HpcH_HpaI PF03328.9 KUM64619.1 - 3.9e-34 117.4 0.3 5.3e-34 117.0 0.2 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.13 KUM64619.1 - 0.0013 17.7 0.1 0.032 13.0 0.1 2.5 1 1 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain MFS_1 PF07690.11 KUM64620.1 - 3.1e-39 134.6 19.3 3.1e-39 134.6 13.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 KUM64621.1 - 9.9e-17 60.6 0.9 1.5e-16 60.1 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NDUFA12 PF05071.11 KUM64622.1 - 8.5e-25 87.2 0.2 1.1e-24 86.8 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 WHIM2 PF15613.1 KUM64622.1 - 0.045 13.6 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 Abhydrolase_6 PF12697.2 KUM64625.1 - 3.5e-23 82.6 0.9 4e-23 82.5 0.6 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM64625.1 - 8.3e-07 28.8 0.0 9.7e-07 28.6 0.0 1.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM64625.1 - 3.7e-05 23.3 0.0 6e-05 22.7 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 KUM64625.1 - 0.0021 17.7 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_8 PF06259.7 KUM64625.1 - 0.0056 16.1 0.0 0.0092 15.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase DUF900 PF05990.7 KUM64625.1 - 0.017 14.4 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PE-PPE PF08237.6 KUM64625.1 - 0.12 11.8 0.0 0.23 10.8 0.0 1.5 2 0 0 2 2 2 0 PE-PPE domain DDOST_48kD PF03345.9 KUM64626.1 - 4.1e-164 546.1 0.0 4.6e-164 545.9 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Pilus_PilP PF11356.3 KUM64626.1 - 0.086 13.0 0.1 1.2 9.4 0.0 2.2 2 0 0 2 2 2 0 Type IV pilus biogenesis 2OG-FeII_Oxy PF03171.15 KUM64627.1 - 2.2e-12 47.1 0.0 3.9e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KUM64627.1 - 1.2e-08 35.5 0.0 2.9e-08 34.2 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal adh_short PF00106.20 KUM64628.1 - 2e-27 96.1 0.1 2.7e-27 95.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM64628.1 - 3.5e-19 69.5 0.2 4.4e-19 69.2 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM64628.1 - 9.3e-10 38.4 0.1 1.6e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM64628.1 - 6.7e-08 32.2 0.3 1.3e-07 31.3 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KUM64628.1 - 0.0001 21.2 0.1 0.00014 20.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 KUM64628.1 - 0.0011 18.0 0.2 0.0018 17.3 0.1 1.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase Gtr1_RagA PF04670.7 KUM64628.1 - 0.013 14.6 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region NAD_binding_10 PF13460.1 KUM64628.1 - 0.021 14.8 1.8 0.2 11.6 0.8 2.6 2 1 0 2 2 2 0 NADH(P)-binding ACT_7 PF13840.1 KUM64628.1 - 0.021 14.3 0.1 0.22 11.0 0.0 2.4 2 0 0 2 2 2 0 ACT domain Ldh_1_N PF00056.18 KUM64628.1 - 0.096 12.5 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain LTV PF04180.9 KUM64629.1 - 4e-71 240.7 2.9 8.7e-71 239.6 2.0 1.5 1 1 0 1 1 1 1 Low temperature viability protein MMR_HSR1 PF01926.18 KUM64630.1 - 3.6e-17 62.3 0.2 1.6e-14 53.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KUM64630.1 - 7.1e-07 28.6 0.1 3.2e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 KUM64630.1 - 0.00037 19.7 0.0 0.00077 18.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KUM64630.1 - 0.0022 17.8 4.8 0.17 11.7 0.2 3.4 3 1 1 4 4 4 2 Dynamin family AIG1 PF04548.11 KUM64630.1 - 0.0072 15.4 1.2 0.0086 15.1 0.0 1.7 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 KUM64630.1 - 0.042 14.3 0.0 0.23 11.9 0.0 2.3 1 0 0 1 1 1 0 Miro-like protein Glyco_transf_25 PF01755.12 KUM64630.1 - 0.059 13.0 0.8 0.17 11.4 0.5 1.7 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) PLDc_2 PF13091.1 KUM64631.1 - 1.9e-13 50.2 0.0 3.4e-06 26.8 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KUM64631.1 - 1.4e-08 34.2 0.4 0.026 14.3 0.4 3.4 2 1 0 2 2 2 2 Phospholipase D Active site motif HAD_2 PF13419.1 KUM64632.1 - 2.7e-22 79.8 0.0 3.2e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KUM64632.1 - 3.8e-08 34.0 0.1 7.5e-08 33.0 0.1 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KUM64632.1 - 0.00014 22.1 0.1 0.00019 21.6 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KUM64632.1 - 0.0015 18.1 0.0 0.0028 17.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Glyco_hydro_3_C PF01915.17 KUM64632.1 - 0.023 14.1 0.1 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain DUF2608 PF11019.3 KUM64632.1 - 0.044 12.7 0.0 1 8.2 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2608) Acid_PPase PF12689.2 KUM64632.1 - 0.057 13.0 0.0 0.67 9.5 0.0 2.2 2 0 0 2 2 2 0 Acid Phosphatase Hydrolase_3 PF08282.7 KUM64632.1 - 0.11 12.0 0.2 11 5.5 0.0 2.7 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase TPR_11 PF13414.1 KUM64633.1 - 2.3e-07 30.3 11.2 0.00094 18.7 0.0 5.1 5 1 1 6 6 6 3 TPR repeat TPR_12 PF13424.1 KUM64633.1 - 1.5e-06 27.9 11.8 0.17 11.8 0.1 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 KUM64633.1 - 1.6e-05 25.0 21.4 3.4 8.5 0.1 8.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.23 KUM64633.1 - 5.1e-05 22.6 7.2 2 8.1 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 KUM64633.1 - 0.0001 21.9 16.3 1.8 8.7 0.1 7.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 KUM64633.1 - 0.00015 22.3 15.5 0.23 12.1 0.1 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 KUM64633.1 - 0.0016 18.4 0.2 11 6.5 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KUM64633.1 - 0.0033 17.7 8.2 0.29 11.5 0.1 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KUM64633.1 - 0.0054 16.4 6.5 16 5.5 0.1 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.1 KUM64633.1 - 0.0058 16.3 6.6 4 7.4 0.0 5.9 7 0 0 7 7 7 1 Tetratricopeptide repeat MBOAT_2 PF13813.1 KUM64634.1 - 5.8e-21 74.3 3.3 5.8e-21 74.3 2.3 2.3 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family RIX1 PF08167.7 KUM64635.1 - 3.4e-61 205.7 3.6 5.5e-61 205.0 0.6 2.6 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis zf-C2H2 PF00096.21 KUM64636.1 - 0.074 13.4 0.8 0.074 13.4 0.6 4.0 3 1 1 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KUM64636.1 - 0.74 10.2 13.7 2.5 8.6 0.6 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger DUF629 PF04780.7 KUM64636.1 - 5.6 5.3 5.5 13 4.1 0.2 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF629) EST1_DNA_bind PF10373.4 KUM64637.1 - 8.5e-65 218.7 0.8 4e-64 216.5 0.1 2.0 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.4 KUM64637.1 - 1.1e-20 73.9 0.1 4.4e-20 72.0 0.1 2.0 2 0 0 2 2 2 1 Telomerase activating protein Est1 TPR_11 PF13414.1 KUM64637.1 - 0.072 12.7 0.4 0.16 11.6 0.3 1.5 1 0 0 1 1 1 0 TPR repeat PfkB PF00294.19 KUM64638.1 - 1.5e-64 218.0 0.1 1.7e-64 217.8 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KUM64638.1 - 0.0078 15.4 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DUF1770 PF08589.5 KUM64639.1 - 1.5e-26 92.8 0.7 2.2e-26 92.3 0.5 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) WHIM1 PF15612.1 KUM64640.1 - 0.00088 19.1 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Ribosomal_L2_C PF03947.13 KUM64641.1 - 9.1e-39 132.2 4.1 1.5e-38 131.5 2.9 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KUM64641.1 - 3.2e-12 46.2 0.0 7e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Amidohydro_3 PF07969.6 KUM64642.1 - 1.5e-58 198.9 0.1 1.8e-58 198.7 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 KUM64642.1 - 2.1e-10 40.7 0.2 1.2e-09 38.3 0.1 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KUM64642.1 - 6e-07 29.7 0.5 0.00078 19.5 0.2 3.2 2 2 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 KUM64642.1 - 7.3e-07 28.9 0.0 3.2e-06 26.8 0.0 2.2 1 0 0 1 1 1 1 Amidohydrolase Fungal_trans_2 PF11951.3 KUM64643.1 - 5.6e-15 54.8 0.5 6.7e-15 54.5 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 KUM64645.1 - 2.5e-15 56.0 5.1 4.2e-15 55.3 0.7 2.7 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KUM64645.1 - 3.2e-12 46.0 8.6 2e-05 24.6 1.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KUM64645.1 - 7.2e-09 35.5 2.4 7.2e-09 35.5 1.6 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KUM64645.1 - 3.1e-08 33.3 11.8 0.00027 21.0 2.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KUM64645.1 - 6.5e-05 22.9 2.0 0.27 11.4 0.5 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 KUM64645.1 - 0.0002 20.9 1.9 0.21 11.2 0.1 2.9 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.1 KUM64645.1 - 0.022 14.6 4.4 1.5 8.8 0.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 KUM64645.1 - 0.045 13.8 2.0 0.093 12.8 1.4 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 KUM64645.1 - 0.096 12.9 3.8 7.8 6.8 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type gag_pre-integrs PF13976.1 KUM64645.1 - 0.59 9.8 4.4 1.8 8.2 0.3 2.8 1 1 1 2 2 2 0 GAG-pre-integrase domain Abhydrolase_3 PF07859.8 KUM64646.1 - 1.4e-37 129.3 0.0 8.5e-36 123.5 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KUM64646.1 - 5.2e-07 28.6 0.0 3.6e-06 25.8 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KUM64646.1 - 0.027 14.2 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family T2SN PF01203.14 KUM64646.1 - 0.055 13.0 0.1 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein N HATPase_c PF02518.21 KUM64647.1 - 8.9e-29 99.4 0.0 2.5e-28 97.9 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KUM64647.1 - 1.3e-20 73.4 0.1 7.3e-20 71.0 0.0 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KUM64647.1 - 3.4e-19 68.6 0.0 1.3e-18 66.7 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.1 KUM64647.1 - 2.5e-12 47.5 0.0 5.5e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 GAF domain AAA_16 PF13191.1 KUM64647.1 - 3.7e-12 46.6 2.0 1.6e-10 41.2 0.0 3.5 3 0 0 3 3 3 1 AAA ATPase domain GAF_3 PF13492.1 KUM64647.1 - 1.2e-08 35.0 0.0 8.1e-08 32.4 0.0 2.2 2 0 0 2 2 2 1 GAF domain Pkinase PF00069.20 KUM64647.1 - 5.8e-06 25.6 0.0 2.4e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain GAF PF01590.21 KUM64647.1 - 7.6e-06 26.1 0.0 0.00015 21.9 0.0 2.6 2 0 0 2 2 2 1 GAF domain HATPase_c_3 PF13589.1 KUM64647.1 - 0.0027 17.3 0.0 0.0067 16.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_35 PF14516.1 KUM64647.1 - 0.0041 15.7 0.0 0.44 9.1 0.0 2.8 2 1 1 3 3 3 1 AAA-like domain NB-ARC PF00931.17 KUM64647.1 - 0.0073 15.2 0.2 2.9 6.6 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain NACHT PF05729.7 KUM64647.1 - 0.017 14.7 1.7 0.37 10.4 1.1 2.4 1 1 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 KUM64647.1 - 0.051 13.7 0.1 3.2 7.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain Cyto_ox_2 PF02322.10 KUM64648.1 - 0.17 10.9 3.2 0.25 10.4 2.2 1.1 1 0 0 1 1 1 0 Cytochrome oxidase subunit II CENP-H PF05837.7 KUM64650.1 - 3.4e-29 101.1 6.9 3.4e-29 101.1 4.8 2.1 2 0 0 2 2 2 1 Centromere protein H (CENP-H) ATG11 PF10377.4 KUM64651.1 - 3.7e-40 136.8 2.0 7.3e-40 135.8 0.0 2.8 2 0 0 2 2 2 1 Autophagy-related protein 11 APG17 PF04108.7 KUM64651.1 - 3.4e-05 22.8 1.0 3.4e-05 22.8 0.7 5.8 3 2 2 5 5 5 2 Autophagy protein Apg17 Myosin_tail_1 PF01576.14 KUM64651.1 - 4e-05 21.5 20.2 4e-05 21.5 14.0 4.4 5 0 0 5 5 5 1 Myosin tail TelA PF05816.6 KUM64651.1 - 4.6e-05 22.2 6.2 4.6e-05 22.2 4.3 5.4 5 1 0 5 5 5 1 Toxic anion resistance protein (TelA) GAS PF13851.1 KUM64651.1 - 0.0022 17.2 11.6 0.0022 17.2 8.0 6.3 5 2 2 7 7 7 1 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 KUM64651.1 - 0.0061 16.4 7.8 0.0061 16.4 5.4 7.6 6 3 1 7 7 7 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ssu72 PF04722.8 KUM64651.1 - 0.034 13.4 2.2 0.084 12.1 1.5 1.7 1 0 0 1 1 1 0 Ssu72-like protein Pox_A_type_inc PF04508.7 KUM64651.1 - 1.3 8.9 0.0 1.3 8.9 0.0 6.2 6 1 0 6 6 6 0 Viral A-type inclusion protein repeat Reo_sigmaC PF04582.7 KUM64651.1 - 3.9 6.5 30.1 0.026 13.7 3.0 4.5 5 1 0 5 5 5 0 Reovirus sigma C capsid protein HMG_box PF00505.14 KUM64652.1 - 1.5e-24 85.9 2.3 1.5e-24 85.9 1.6 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KUM64652.1 - 1.7e-18 66.7 1.2 1.7e-18 66.7 0.8 1.8 2 1 0 2 2 2 1 HMG-box domain HMG_box_5 PF14887.1 KUM64652.1 - 0.038 13.7 2.3 0.089 12.5 1.6 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box 5 DUF1014 PF06244.7 KUM64652.1 - 0.088 13.0 3.3 0.12 12.6 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) Allantoicase PF03561.10 KUM64654.1 - 5e-87 289.0 0.0 6.6e-47 158.7 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat Pkinase PF00069.20 KUM64656.1 - 1.3e-74 250.5 0.0 2.1e-74 249.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM64656.1 - 9.6e-40 136.2 0.0 1.9e-39 135.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 KUM64656.1 - 1.5e-17 62.7 0.3 2.5e-17 62.0 0.2 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 KUM64656.1 - 7.9e-06 25.0 0.0 1.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KUM64656.1 - 6.5e-05 22.0 0.0 0.00092 18.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KUM64656.1 - 0.00062 19.5 0.0 0.0027 17.4 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.6 KUM64656.1 - 0.015 14.5 0.2 0.024 13.8 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.4 KUM64656.1 - 0.029 13.6 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL OPT PF03169.10 KUM64657.1 - 3.2e-69 233.9 18.5 3.9e-69 233.7 12.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Proteasom_Rpn13 PF04683.8 KUM64658.1 - 4.6e-29 100.3 0.0 7.4e-29 99.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Ion_trans PF00520.26 KUM64659.1 - 2.5e-98 327.2 80.3 1.6e-35 122.1 3.5 5.4 5 1 0 5 5 5 4 Ion transport protein EF-hand_1 PF00036.27 KUM64659.1 - 0.0081 15.3 0.0 0.048 12.9 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 KUM64659.1 - 0.1 12.5 0.0 1.1 9.2 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain ORC6 PF05460.8 KUM64660.1 - 0.61 9.1 7.1 0.64 9.0 4.9 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF605 PF04652.11 KUM64660.1 - 4.6 6.5 12.7 5.3 6.3 8.8 1.1 1 0 0 1 1 1 0 Vta1 like SET PF00856.23 KUM64661.1 - 5.5e-23 82.0 0.1 1.1e-22 81.0 0.1 1.5 1 0 0 1 1 1 1 SET domain Pre-SET PF05033.11 KUM64661.1 - 7.5e-12 45.4 5.0 7.5e-12 45.4 3.5 2.5 2 1 0 2 2 2 1 Pre-SET motif SCIMP PF15050.1 KUM64661.1 - 0.071 13.0 2.7 0.15 11.9 1.9 1.5 1 0 0 1 1 1 0 SCIMP protein Sas10 PF09368.5 KUM64662.1 - 1.3e-27 95.7 10.2 1.3e-27 95.7 7.0 2.4 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 KUM64662.1 - 2.9e-16 59.4 0.0 2.9e-16 59.4 0.0 2.5 3 0 0 3 3 3 1 Sas10/Utp3/C1D family adh_short PF00106.20 KUM64663.1 - 4.5e-19 68.9 0.1 6.5e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM64663.1 - 8.9e-09 35.2 0.0 1.2e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KUM64663.1 - 6.3e-06 26.1 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KUM64663.1 - 3.5e-05 23.8 1.1 0.0001 22.3 0.7 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KUM64663.1 - 7.3e-05 22.3 0.2 0.00016 21.2 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 KUM64663.1 - 0.0022 17.0 0.2 0.004 16.2 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 KUM64663.1 - 0.012 15.4 0.3 0.053 13.3 0.3 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 KUM64663.1 - 0.016 15.3 0.1 0.031 14.3 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 KUM64663.1 - 0.033 14.0 0.1 0.056 13.2 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DFP PF04127.10 KUM64663.1 - 0.054 13.1 0.3 0.094 12.3 0.2 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein F420_oxidored PF03807.12 KUM64663.1 - 0.077 13.4 0.1 0.17 12.3 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 KUM64663.1 - 0.13 12.5 0.2 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding FA_hydroxylase PF04116.8 KUM64664.1 - 2e-12 47.5 10.0 2e-12 47.5 6.9 2.4 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribosomal_L6e PF01159.14 KUM64665.1 - 6.3e-38 129.3 0.3 1e-37 128.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e Imm44 PF15584.1 KUM64665.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 44 DUF1070 PF06376.7 KUM64665.1 - 0.31 10.9 3.2 0.23 11.3 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1070) EF1_GNE PF00736.14 KUM64666.1 - 4e-32 109.7 3.1 6.9e-32 108.9 2.2 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 KUM64666.1 - 8.3e-12 45.0 3.9 8.3e-12 45.0 2.7 3.0 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 KUM64666.1 - 4.2e-05 23.9 0.0 0.00012 22.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KUM64666.1 - 0.00011 22.1 0.4 0.00034 20.5 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KUM64666.1 - 0.017 15.0 0.3 0.34 10.8 0.2 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain YL1 PF05764.8 KUM64666.1 - 0.9 9.0 7.3 0.17 11.5 2.0 1.7 2 0 0 2 2 2 0 YL1 nuclear protein AAA_2 PF07724.9 KUM64667.1 - 4e-46 157.0 0.0 9.5e-44 149.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 KUM64667.1 - 3.5e-26 90.8 0.2 9.9e-26 89.4 0.1 1.8 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 KUM64667.1 - 5.5e-19 68.6 0.0 3.8e-10 40.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KUM64667.1 - 2.7e-12 46.6 1.0 5.3e-08 32.6 0.0 3.5 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KUM64667.1 - 7.1e-11 42.4 10.7 0.00012 22.1 0.0 5.2 4 2 2 6 6 6 2 AAA ATPase domain AAA_22 PF13401.1 KUM64667.1 - 2.5e-10 40.6 0.9 0.0014 18.7 0.0 3.7 3 1 1 4 4 4 2 AAA domain Sigma54_activat PF00158.21 KUM64667.1 - 3.2e-07 29.9 1.0 0.00025 20.5 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.1 KUM64667.1 - 1.3e-06 28.2 0.0 0.088 12.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 KUM64667.1 - 4.8e-06 26.3 0.1 0.11 12.1 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_17 PF13207.1 KUM64667.1 - 2.5e-05 25.0 7.8 0.096 13.5 0.0 4.8 5 1 0 5 5 4 2 AAA domain AAA_28 PF13521.1 KUM64667.1 - 3.8e-05 23.7 1.4 0.021 14.7 0.0 3.6 3 1 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 KUM64667.1 - 6.3e-05 22.7 7.4 0.1 12.2 0.1 4.6 3 2 0 3 3 2 1 Archaeal ATPase MobB PF03205.9 KUM64667.1 - 7e-05 22.5 0.0 0.048 13.3 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KUM64667.1 - 9.2e-05 22.7 3.0 0.32 11.2 0.0 3.2 3 0 0 3 3 2 2 AAA domain TrwB_AAD_bind PF10412.4 KUM64667.1 - 0.00016 20.4 0.1 0.07 11.7 0.0 2.8 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain AAA_19 PF13245.1 KUM64667.1 - 0.00019 21.1 0.0 0.011 15.4 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain IstB_IS21 PF01695.12 KUM64667.1 - 0.00025 20.5 0.0 0.97 8.8 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein SRP54 PF00448.17 KUM64667.1 - 0.00028 20.3 0.1 0.052 12.9 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain RNA_helicase PF00910.17 KUM64667.1 - 0.0013 18.8 0.0 0.75 9.9 0.0 2.8 2 1 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 KUM64667.1 - 0.0035 16.7 1.1 0.9 8.9 0.1 3.1 2 2 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KUM64667.1 - 0.005 17.1 1.1 2.1 8.6 0.0 3.3 3 0 0 3 3 3 1 ABC transporter PduV-EutP PF10662.4 KUM64667.1 - 0.0069 15.8 0.0 0.32 10.4 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 KUM64667.1 - 0.0097 15.5 0.0 0.44 10.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KUM64667.1 - 0.011 14.9 0.2 2.5 7.1 0.0 3.1 2 1 1 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KUM64667.1 - 0.011 15.5 0.1 4.7 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KUM64667.1 - 0.017 14.5 0.0 0.29 10.5 0.0 2.7 2 1 0 2 2 2 0 AAA-like domain ResIII PF04851.10 KUM64667.1 - 0.02 14.7 6.8 1.8 8.3 0.0 3.6 3 2 1 4 4 3 0 Type III restriction enzyme, res subunit ATP_bind_1 PF03029.12 KUM64667.1 - 0.022 14.2 0.1 0.38 10.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF853 PF05872.7 KUM64667.1 - 0.025 12.9 0.1 0.025 12.9 0.1 2.3 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF853) DUF815 PF05673.8 KUM64667.1 - 0.029 13.2 0.6 0.61 8.9 0.1 3.0 3 1 0 3 3 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.1 KUM64667.1 - 0.033 13.7 5.1 0.21 11.1 0.0 3.8 3 1 1 5 5 4 0 AAA domain UPF0079 PF02367.12 KUM64667.1 - 0.033 13.8 0.1 8.6 6.0 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 KUM64667.1 - 0.036 13.2 0.0 5.9 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 KUM64667.1 - 0.039 13.0 2.0 0.56 9.2 0.0 2.8 3 0 0 3 3 2 0 Zeta toxin UvrD-helicase PF00580.16 KUM64667.1 - 0.059 12.6 2.9 0.35 10.1 0.1 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain GAS PF13851.1 KUM64667.1 - 0.074 12.2 8.8 0.17 11.0 6.1 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Nckap1 PF09735.4 KUM64667.1 - 0.11 9.8 0.0 0.18 9.2 0.0 1.1 1 0 0 1 1 1 0 Membrane-associated apoptosis protein DUF948 PF06103.6 KUM64667.1 - 0.14 11.9 3.5 3.3 7.6 0.6 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) AAA_29 PF13555.1 KUM64667.1 - 0.18 11.3 0.0 10 5.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF2968 PF11180.3 KUM64667.1 - 0.18 11.1 10.5 0.38 10.1 7.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Miro PF08477.8 KUM64667.1 - 0.27 11.7 2.2 4.1 7.9 0.0 2.9 3 0 0 3 3 2 0 Miro-like protein Bacillus_HBL PF05791.6 KUM64667.1 - 0.49 9.7 3.8 1 8.7 2.7 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) APG6 PF04111.7 KUM64667.1 - 0.71 8.8 8.2 1.3 8.0 5.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 KUM64667.1 - 0.72 8.7 9.1 1.5 7.6 6.3 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 OEP PF02321.13 KUM64667.1 - 2.3 7.7 12.7 4.8 6.7 8.8 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein V_ATPase_I PF01496.14 KUM64667.1 - 4.1 5.1 5.2 5.8 4.6 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MutS_V PF00488.16 KUM64668.1 - 3.5e-25 88.7 0.0 5.7e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KUM64668.1 - 5.7e-17 62.1 0.0 7.9e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 MutS domain III AAA_29 PF13555.1 KUM64668.1 - 0.0019 17.6 0.4 0.16 11.5 0.0 3.1 2 1 1 3 3 3 1 P-loop containing region of AAA domain MutS_IV PF05190.13 KUM64668.1 - 0.0054 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV MutS_V PF00488.16 KUM64669.1 - 8.8e-24 84.2 0.0 1e-23 83.9 0.0 1.0 1 0 0 1 1 1 1 MutS domain V DUF585 PF04522.7 KUM64670.1 - 0.07 12.5 0.0 0.077 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF585) AAT PF03417.11 KUM64671.1 - 1.4e-17 63.9 0.0 1.7e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase AMP-binding PF00501.23 KUM64672.1 - 5.1e-79 265.6 0.0 1.2e-78 264.4 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme KR PF08659.5 KUM64672.1 - 2.1e-52 177.4 0.1 2.4e-51 173.9 0.0 2.5 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 KUM64672.1 - 6.7e-50 170.2 0.0 1.1e-49 169.5 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KUM64672.1 - 2.9e-47 161.2 0.2 5.1e-47 160.4 0.2 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KUM64672.1 - 1.2e-44 152.1 0.3 6.7e-42 143.2 0.0 3.3 3 0 0 3 3 3 1 short chain dehydrogenase Condensation PF00668.15 KUM64672.1 - 9e-44 149.5 0.0 1.5e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 Condensation domain NAD_binding_4 PF07993.7 KUM64672.1 - 1.2e-38 132.4 0.0 2.8e-38 131.2 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 KUM64672.1 - 9e-29 99.7 0.0 1.9e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KUM64672.1 - 2.2e-18 66.5 0.0 6.2e-18 65.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KUM64672.1 - 7.5e-16 58.1 0.9 2.2e-09 37.4 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Epimerase PF01370.16 KUM64672.1 - 5.8e-15 55.3 0.0 2.1e-12 47.0 0.0 3.0 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.1 KUM64672.1 - 2.3e-13 50.1 0.0 6.6e-13 48.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM64672.1 - 1.2e-11 44.8 0.0 3.6e-11 43.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 KUM64672.1 - 4.9e-11 42.7 0.0 1.7e-10 41.0 0.0 2.0 1 0 0 1 1 1 1 HxxPF-repeated domain 3Beta_HSD PF01073.14 KUM64672.1 - 1.6e-10 40.1 0.0 0.00014 20.6 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_31 PF13847.1 KUM64672.1 - 1.7e-10 40.7 0.0 4e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM64672.1 - 1.5e-09 38.3 0.0 4.9e-08 33.5 0.0 3.3 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KUM64672.1 - 9.1e-09 34.7 0.0 3e-08 33.0 0.0 1.8 2 0 0 2 2 1 1 ubiE/COQ5 methyltransferase family ketoacyl-synt PF00109.21 KUM64672.1 - 2.4e-06 27.2 0.0 5.5e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Methyltransf_16 PF10294.4 KUM64672.1 - 0.00036 20.0 0.0 0.001 18.5 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase adh_short_C2 PF13561.1 KUM64672.1 - 0.0005 19.9 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KUM64672.1 - 0.0033 17.4 0.0 0.0098 15.9 0.0 1.8 1 0 0 1 1 1 1 NADH(P)-binding RrnaAD PF00398.15 KUM64672.1 - 0.0037 16.3 0.1 0.011 14.7 0.0 1.8 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Semialdhyde_dh PF01118.19 KUM64672.1 - 0.01 16.1 0.0 0.049 13.9 0.0 2.2 2 0 0 2 2 1 0 Semialdehyde dehydrogenase, NAD binding domain Methyltransf_PK PF05891.7 KUM64672.1 - 0.016 14.5 0.0 0.039 13.2 0.0 1.5 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase RmlD_sub_bind PF04321.12 KUM64672.1 - 0.26 10.1 0.0 5.9 5.6 0.0 2.7 3 0 0 3 3 3 0 RmlD substrate binding domain Glyco_hyd_65N_2 PF14498.1 KUM64673.1 - 1.6e-62 211.2 0.0 2.3e-62 210.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Sugar_tr PF00083.19 KUM64674.1 - 3.2e-60 204.0 28.7 3.9e-60 203.7 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM64674.1 - 1.1e-24 86.7 29.4 1.5e-24 86.4 20.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily NAAA-beta PF15508.1 KUM64675.1 - 2.9e-05 24.3 0.0 3.6e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Glyco_hydro_1 PF00232.13 KUM64676.1 - 2.5e-148 494.0 1.8 2.9e-148 493.8 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DUF221 PF02714.10 KUM64677.1 - 1.7e-93 313.0 18.4 1.7e-93 313.0 12.8 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KUM64677.1 - 8.2e-44 148.9 1.4 8.2e-44 148.9 1.0 2.6 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KUM64677.1 - 8.2e-17 61.5 0.0 1.8e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF2823 PF11034.3 KUM64678.1 - 7.9e-30 102.7 13.6 9.7e-30 102.5 9.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) DUF885 PF05960.6 KUM64679.1 - 1.2e-51 176.5 0.0 1.6e-51 176.1 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) OPT PF03169.10 KUM64680.1 - 2.4e-96 323.6 23.4 2.7e-96 323.4 16.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein HTH_40 PF14493.1 KUM64680.1 - 0.0082 16.3 0.1 0.015 15.5 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain DUF4078 PF13300.1 KUM64681.1 - 7.8e-30 102.8 10.3 7.8e-30 102.8 7.1 3.1 3 1 0 3 3 3 1 Domain of unknown function (DUF4078) Vault PF01505.13 KUM64681.1 - 1.5 8.9 5.2 1.5 8.8 0.7 2.5 2 0 0 2 2 2 0 Major Vault Protein repeat COX16 PF14138.1 KUM64681.1 - 5.6 7.1 10.5 2.1 8.5 4.1 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Homoserine_dh PF00742.14 KUM64682.1 - 7.8e-52 175.5 0.0 1e-51 175.1 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 KUM64682.1 - 1e-13 51.7 0.0 1.9e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF3445 PF11927.3 KUM64683.1 - 3.6e-84 282.0 0.0 4.2e-84 281.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) FSH1 PF03959.8 KUM64684.1 - 2.8e-56 190.2 0.0 3.2e-56 190.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KUM64684.1 - 6.1e-07 29.3 0.1 8.7e-07 28.7 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KUM64684.1 - 9.7e-06 25.1 0.7 0.0019 17.7 0.0 2.7 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KUM64684.1 - 0.00011 22.1 1.2 0.0066 16.3 0.8 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KUM64684.1 - 0.0026 17.0 0.0 0.0037 16.5 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 KUM64684.1 - 0.0078 15.4 0.0 0.018 14.3 0.0 1.7 1 1 0 1 1 1 1 Esterase PHB depolymerase ASFV_J13L PF05568.6 KUM64686.1 - 0.022 14.2 4.4 0.044 13.3 0.2 2.3 1 1 1 2 2 2 0 African swine fever virus J13L protein SET PF00856.23 KUM64687.1 - 2.1e-09 37.8 0.2 1.6e-08 35.0 0.1 2.3 1 1 0 1 1 1 1 SET domain Ribosomal_S14 PF00253.16 KUM64687.1 - 0.064 12.6 3.5 2.4 7.6 0.2 2.5 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e UIM PF02809.15 KUM64688.1 - 0.019 14.4 0.7 0.067 12.7 0.5 2.0 1 0 0 1 1 1 0 Ubiquitin interaction motif Response_reg PF00072.19 KUM64690.1 - 7.6e-20 70.9 0.0 4.6e-13 49.1 0.0 2.2 2 0 0 2 2 2 2 Response regulator receiver domain Fungal_trans_2 PF11951.3 KUM64691.1 - 1.9e-05 23.4 4.3 5.6e-05 21.9 0.0 2.6 3 0 0 3 3 3 2 Fungal specific transcription factor domain FimP PF09766.4 KUM64691.1 - 0.17 10.8 3.1 0.29 10.1 0.0 2.0 2 0 0 2 2 2 0 Fms-interacting protein Cu-oxidase_3 PF07732.10 KUM64692.1 - 2.9e-39 133.4 1.9 2.9e-39 133.4 1.3 2.6 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KUM64692.1 - 6.4e-36 122.8 0.9 6.4e-36 122.8 0.6 3.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KUM64692.1 - 4.3e-28 98.2 2.0 8.4e-22 77.7 0.1 3.4 3 1 1 4 4 4 2 Multicopper oxidase SH3_1 PF00018.23 KUM64693.1 - 2.8e-09 36.2 0.1 4.4e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KUM64693.1 - 4e-07 29.4 0.0 8.4e-07 28.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KUM64693.1 - 2.9e-06 26.7 0.0 5.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF165 PF02592.10 KUM64693.1 - 0.049 13.8 0.0 0.065 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized ACR, YhhQ family COG1738 Bac_chlorC PF02043.12 KUM64693.1 - 0.6 9.9 3.6 0.5 10.1 0.4 2.3 2 1 0 2 2 2 0 Bacteriochlorophyll C binding protein ADH_zinc_N PF00107.21 KUM64694.1 - 7.9e-26 90.1 0.6 1.3e-25 89.4 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KUM64694.1 - 1.2e-14 55.2 0.1 2.6e-14 54.1 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM64694.1 - 5.5e-09 35.7 0.2 1.1e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 KUM64694.1 - 0.033 13.7 0.3 0.033 13.7 0.2 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 KUM64694.1 - 0.053 13.5 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain ALIX_LYPXL_bnd PF13949.1 KUM64695.1 - 0.09 11.7 0.1 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV DUF1143 PF06608.6 KUM64696.1 - 0.015 15.2 0.5 0.54 10.2 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1143) ACC_epsilon PF13822.1 KUM64696.1 - 0.37 11.1 1.9 15 5.9 0.1 2.1 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Pkinase PF00069.20 KUM64697.1 - 5.3e-24 84.7 0.0 1.1e-23 83.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM64697.1 - 2.8e-14 52.8 0.0 2.3e-13 49.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase AA_permease PF00324.16 KUM64698.1 - 2e-15 56.1 11.0 2.4e-14 52.5 7.6 2.3 1 1 0 1 1 1 1 Amino acid permease TraL PF07178.6 KUM64698.1 - 1.3 9.0 4.8 0.43 10.6 0.4 2.5 2 1 0 2 2 2 0 TraL protein Metallophos PF00149.23 KUM64699.1 - 1.9e-09 37.2 0.1 9.5e-09 34.9 0.1 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KUM64699.1 - 5.8e-07 29.4 0.0 9.9e-07 28.7 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FAD_binding_4 PF01565.18 KUM64700.1 - 2.3e-19 69.2 1.3 4.1e-19 68.4 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KUM64700.1 - 9.8e-13 47.7 2.0 1.8e-12 46.9 1.4 1.5 1 0 0 1 1 1 1 Berberine and berberine like CoA_binding_2 PF13380.1 KUM64700.1 - 0.052 13.7 0.2 0.22 11.6 0.2 2.0 1 1 0 1 1 1 0 CoA binding domain DapB_N PF01113.15 KUM64700.1 - 0.14 12.0 0.0 0.95 9.3 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus WD-3 PF09765.4 KUM64701.1 - 0.018 14.3 0.2 0.021 14.0 0.1 1.0 1 0 0 1 1 1 0 WD-repeat region Pkinase PF00069.20 KUM64702.1 - 1.3e-63 214.6 0.0 1.6e-63 214.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM64702.1 - 1.6e-36 125.7 0.0 2e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KUM64702.1 - 0.0057 15.7 0.0 0.0093 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KUM64702.1 - 0.0064 15.4 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KUM64702.1 - 0.024 14.3 0.1 0.1 12.2 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KUM64702.1 - 0.053 12.3 0.0 0.078 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Abhydrolase_1 PF00561.15 KUM64704.1 - 7.1e-19 68.2 0.0 5e-18 65.5 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KUM64704.1 - 1e-12 48.4 0.8 2.9e-11 43.6 0.6 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KUM64704.1 - 0.00076 18.9 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Glyco_hydro_43 PF04616.9 KUM64705.1 - 6.1e-32 110.8 0.1 1.2e-31 109.8 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 KUM64705.1 - 1.3e-05 24.7 1.0 0.00012 21.5 0.3 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Gly_transf_sug PF04488.10 KUM64706.1 - 4.7e-12 46.1 0.0 8.1e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif PEMT PF04191.8 KUM64706.1 - 0.17 11.9 0.2 0.88 9.7 0.0 2.1 3 0 0 3 3 3 0 Phospholipid methyltransferase CNH PF00780.17 KUM64708.1 - 2.4e-82 276.4 0.0 4.7e-82 275.4 0.0 1.5 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 KUM64708.1 - 4.9e-43 146.3 0.0 1.1e-42 145.1 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 KUM64708.1 - 7.2e-38 130.2 0.0 1.4e-37 129.3 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 KUM64708.1 - 5.9e-12 45.1 0.0 1.7e-11 43.6 0.0 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ATP-synt_C PF00137.16 KUM64709.1 - 5e-23 80.7 34.2 6.9e-14 51.5 6.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Spermine_synth PF01564.12 KUM64710.1 - 2.6e-09 36.3 0.0 4.3e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 KUM64710.1 - 0.037 14.6 0.0 0.069 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.6 KUM64710.1 - 0.075 12.7 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase DLIC PF05783.6 KUM64711.1 - 2.3e-38 132.0 0.1 1.6e-36 126.0 0.0 2.9 2 1 1 3 3 3 2 Dynein light intermediate chain (DLIC) AMP-binding PF00501.23 KUM64712.1 - 2e-91 306.4 0.0 2.5e-91 306.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KUM64712.1 - 3.3e-16 59.9 0.0 8.1e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2052 PF09747.4 KUM64713.1 - 7.6e-27 94.4 10.3 3.7e-26 92.1 7.1 1.8 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Septin PF00735.13 KUM64715.1 - 3.2e-106 354.4 0.2 6.3e-106 353.5 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KUM64715.1 - 0.00012 22.0 0.0 0.00026 20.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KUM64715.1 - 0.0019 17.6 0.0 0.066 12.6 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KUM64715.1 - 0.0021 17.2 0.1 0.0057 15.8 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KUM64715.1 - 0.008 16.0 5.3 0.9 9.3 0.0 2.9 2 1 1 3 3 3 2 Dynamin family Miro PF08477.8 KUM64715.1 - 0.029 14.8 0.0 0.1 13.1 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein IIGP PF05049.8 KUM64715.1 - 0.056 12.2 0.0 0.1 11.3 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.1 KUM64715.1 - 0.06 13.4 0.1 0.21 11.7 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KUM64715.1 - 0.15 12.9 4.7 0.32 11.8 0.1 2.8 2 2 0 2 2 2 0 AAA domain EB1 PF03271.12 KUM64715.1 - 0.3 11.1 3.2 5.1 7.2 0.6 2.6 2 0 0 2 2 2 0 EB1-like C-terminal motif FtsK_SpoIIIE PF01580.13 KUM64715.1 - 0.31 10.4 0.1 0.31 10.4 0.1 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family RRM_1 PF00076.17 KUM64716.1 - 1.2e-19 69.7 0.0 3e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM64716.1 - 1.5e-14 53.6 0.0 2.6e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM64716.1 - 2.3e-06 27.3 0.0 3.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 KUM64716.1 - 0.12 11.9 0.4 0.51 9.8 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain FUSC PF04632.7 KUM64716.1 - 1.2 7.4 3.4 1.6 7.0 2.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family WD40 PF00400.27 KUM64717.1 - 6e-10 38.6 1.0 0.00049 19.8 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Nbas_N PF15492.1 KUM64717.1 - 0.0004 19.5 0.0 0.039 13.0 0.0 2.4 1 1 1 2 2 2 2 Neuroblastoma-amplified sequence, N terminal Apc4_WD40 PF12894.2 KUM64717.1 - 0.0022 17.4 0.0 2.2 7.8 0.0 2.7 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.7 KUM64717.1 - 0.021 12.6 0.0 0.05 11.4 0.0 1.5 1 1 1 2 2 2 0 IKI3 family CH PF00307.26 KUM64718.1 - 1.9e-36 124.3 0.0 6.1e-18 64.8 0.0 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 KUM64718.1 - 6.3e-21 74.1 0.0 1.6e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 KUM64718.1 - 4.8e-09 35.7 1.7 1.6e-05 24.4 0.0 3.1 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.1 KUM64718.1 - 0.00045 19.8 0.1 0.0031 17.2 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 KUM64718.1 - 0.0027 16.9 0.1 0.022 14.0 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KUM64718.1 - 0.0031 17.0 0.2 0.024 14.2 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain pair Rabaptin PF03528.10 KUM64718.1 - 0.027 14.3 0.0 0.45 10.4 0.0 2.6 1 1 1 2 2 2 0 Rabaptin EF-hand_7 PF13499.1 KUM64718.1 - 0.56 10.3 3.0 2.4 8.3 0.3 3.1 2 1 0 2 2 2 0 EF-hand domain pair RRM_1 PF00076.17 KUM64719.1 - 1.2e-14 53.6 0.0 1.9e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM64719.1 - 2.8e-09 36.8 0.0 4.2e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM64719.1 - 5.8e-05 22.8 0.0 8.8e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KUM64719.1 - 7.8e-05 23.0 8.2 7.8e-05 23.0 5.7 4.4 3 1 1 4 4 4 2 C-terminal duplication domain of Friend of PRMT1 WD40 PF00400.27 KUM64720.1 - 4.1e-34 115.2 10.6 1.2e-10 40.8 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KUM64720.1 - 0.0092 14.3 0.0 0.016 13.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain Me-amine-dh_H PF06433.6 KUM64720.1 - 0.021 13.4 0.0 0.48 9.0 0.0 2.1 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) dsrm PF00035.20 KUM64720.1 - 0.17 12.4 0.0 0.51 10.9 0.0 1.8 1 0 0 1 1 1 0 Double-stranded RNA binding motif PUL PF08324.6 KUM64721.1 - 1.8e-55 187.6 0.0 2.4e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 KUM64721.1 - 2.9e-44 149.8 0.1 5.1e-44 148.9 0.1 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 KUM64721.1 - 3.3e-42 140.9 14.3 9.6e-09 34.8 0.8 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 KUM64721.1 - 0.0014 18.4 0.0 0.17 11.6 0.0 2.8 1 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region YjeF_N PF03853.10 KUM64722.1 - 7.1e-24 84.2 0.0 2.5e-23 82.5 0.0 1.7 1 1 1 2 2 2 1 YjeF-related protein N-terminus GxDLY PF14607.1 KUM64722.1 - 0.13 11.7 0.0 0.28 10.6 0.0 1.5 2 0 0 2 2 2 0 N-terminus of Esterase_SGNH_hydro-type Ribosomal_S16 PF00886.14 KUM64723.1 - 8.9e-25 86.1 0.1 1.1e-24 85.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 RRM_1 PF00076.17 KUM64724.1 - 7.3e-16 57.5 0.0 5.7e-14 51.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM64724.1 - 1.7e-08 34.2 0.0 1.1e-06 28.4 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Bot1p PF12298.3 KUM64725.1 - 1.4e-50 171.6 0.3 1.4e-50 171.6 0.2 1.6 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein Sensor PF13796.1 KUM64726.1 - 0.019 14.5 0.0 0.022 14.3 0.0 1.1 1 0 0 1 1 1 0 Putative sensor DUF3481 PF11980.3 KUM64726.1 - 0.13 12.0 1.1 0.18 11.6 0.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3481) Glyco_hydro_31 PF01055.21 KUM64727.1 - 1e-163 545.2 2.9 1.3e-163 544.9 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KUM64727.1 - 2.6e-10 40.0 1.2 7.9e-10 38.4 0.9 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like MARVEL PF01284.18 KUM64729.1 - 2.3e-18 66.3 10.8 2.9e-18 66.0 7.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain FA_hydroxylase PF04116.8 KUM64729.1 - 0.19 12.1 6.9 1.3 9.4 0.1 2.5 1 1 2 3 3 3 0 Fatty acid hydroxylase superfamily PQ-loop PF04193.9 KUM64729.1 - 0.4 10.2 0.0 0.4 10.2 0.0 2.6 2 1 0 2 2 2 0 PQ loop repeat PepSY_TM_2 PF13703.1 KUM64729.1 - 3 8.0 13.2 1 9.5 1.2 3.2 1 1 2 3 3 3 0 PepSY-associated TM helix UPF0233 PF06781.7 KUM64729.1 - 8 6.1 8.4 1.2 8.8 2.2 2.2 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0233) LCCL PF03815.14 KUM64730.1 - 3.9e-20 71.6 0.0 6.2e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 LCCL domain FUSC PF04632.7 KUM64730.1 - 1.5 7.1 5.6 2.5 6.4 3.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family ADH_zinc_N PF00107.21 KUM64731.1 - 0.0061 16.1 0.0 0.01 15.3 0.0 1.4 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Oxidored_FMN PF00724.15 KUM64732.1 - 2.2e-87 293.2 0.0 2.6e-87 292.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Thiolase_N PF00108.18 KUM64733.1 - 0.12 11.3 1.2 0.25 10.3 0.8 1.6 1 1 0 1 1 1 0 Thiolase, N-terminal domain ThiF PF00899.16 KUM64734.1 - 1.3e-34 118.9 0.0 2.2e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.13 KUM64734.1 - 0.012 15.6 0.0 0.039 13.9 0.0 1.9 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 KUM64734.1 - 0.014 14.8 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DAO PF01266.19 KUM64734.1 - 0.026 13.4 0.2 0.086 11.7 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KUM64734.1 - 0.057 13.0 0.4 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KUM64734.1 - 0.093 11.6 0.4 0.23 10.4 0.3 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_7 PF13241.1 KUM64734.1 - 0.094 12.9 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding CD99L2 PF12301.3 KUM64734.1 - 0.14 11.8 0.2 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 CD99 antigen like protein 2 UDPG_MGDP_dh_N PF03721.9 KUM64734.1 - 0.14 11.5 0.1 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_hydro_17 PF00332.13 KUM64734.1 - 0.21 10.5 0.0 0.33 9.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 PNP_UDP_1 PF01048.15 KUM64737.1 - 7.7e-08 31.5 1.8 1.2e-06 27.7 1.2 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily NB-ARC PF00931.17 KUM64737.1 - 0.001 18.0 0.0 0.0062 15.4 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain Arch_ATPase PF01637.13 KUM64737.1 - 0.013 15.2 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_16 PF13191.1 KUM64737.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KUM64737.1 - 0.045 13.8 0.0 0.09 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Phage_T4_Ndd PF06591.6 KUM64737.1 - 0.092 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) AAA_14 PF13173.1 KUM64737.1 - 0.093 12.6 0.0 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA-ATPase_like PF09820.4 KUM64737.1 - 0.16 11.0 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Predicted AAA-ATPase Fungal_trans PF04082.13 KUM64738.1 - 1.5e-06 27.2 0.0 2.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KUM64739.1 - 5.6e-25 87.8 30.9 5.6e-25 87.8 21.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM64739.1 - 3.3e-08 32.5 12.7 3.3e-08 32.5 8.8 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter ATG22 PF11700.3 KUM64739.1 - 1.9e-05 23.3 27.3 0.0033 15.9 4.9 2.6 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_3 PF05977.8 KUM64739.1 - 0.0018 16.4 10.0 0.0031 15.7 6.9 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector DUF2418 PF10332.4 KUM64739.1 - 0.037 14.3 0.2 0.14 12.4 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2418) DUF3938 PF13074.1 KUM64739.1 - 0.85 9.5 4.4 1.7 8.5 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3938) AMP-binding PF00501.23 KUM64740.1 - 9.1e-72 241.7 0.1 1.4e-71 241.1 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Abhydrolase_6 PF12697.2 KUM64740.1 - 2.9e-11 43.6 0.2 8.4e-11 42.1 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family PP-binding PF00550.20 KUM64740.1 - 1.9e-10 40.8 0.0 5.3e-10 39.4 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KUM64740.1 - 5.4e-09 36.8 0.0 1.9e-08 35.1 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_18 PF12847.2 KUM64740.1 - 2.3e-08 34.6 0.0 6.7e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Thioesterase PF00975.15 KUM64740.1 - 5e-08 33.4 0.0 1e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Methyltransf_23 PF13489.1 KUM64740.1 - 1.1e-07 31.7 0.0 2.9e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_5 PF12695.2 KUM64740.1 - 1.9e-07 30.9 0.0 4.2e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_11 PF08241.7 KUM64740.1 - 2.6e-07 31.0 0.0 8.7e-07 29.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM64740.1 - 8.9e-06 26.0 0.0 3.1e-05 24.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM64740.1 - 2e-05 24.9 0.0 5.6e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KUM64740.1 - 0.021 14.8 0.0 0.077 13.0 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain DUF2755 PF10954.3 KUM64740.1 - 0.024 14.3 0.0 0.059 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) MFS_1 PF07690.11 KUM64742.1 - 2.2e-43 148.3 39.3 2.2e-43 148.3 27.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM64742.1 - 8.4e-12 44.3 21.3 1.7e-11 43.3 14.7 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 KUM64742.1 - 0.0043 15.2 1.4 0.0069 14.5 1.0 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector Corona_S2 PF01601.11 KUM64742.1 - 0.59 8.1 1.9 0.88 7.5 1.3 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Mem_trans PF03547.13 KUM64743.1 - 9.1e-08 30.7 8.3 1.1e-05 23.9 5.8 2.9 1 1 0 1 1 1 1 Membrane transport protein HpcH_HpaI PF03328.9 KUM64744.1 - 4.3e-37 127.1 0.0 5.1e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family ECM1 PF05782.6 KUM64745.1 - 0.14 10.8 0.0 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) DUF1281 PF06924.6 KUM64746.1 - 0.00056 19.3 0.1 0.36 10.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1281) RTTN_N PF14726.1 KUM64746.1 - 0.0077 16.7 2.4 0.88 10.1 0.1 2.9 2 1 1 3 3 3 2 Rotatin, an armadillo repeat protein, centriole functioning DUF383 PF04063.9 KUM64746.1 - 0.043 13.3 0.4 0.14 11.6 0.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF383) DUF4334 PF14232.1 KUM64747.1 - 4e-21 74.4 0.2 6.2e-21 73.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4334) GXWXG PF14231.1 KUM64747.1 - 6.7e-19 67.2 0.1 1e-18 66.6 0.1 1.4 1 0 0 1 1 1 1 GXWXG protein TrkH PF02386.11 KUM64748.1 - 3.7e-122 407.2 15.0 2.6e-120 401.2 5.4 2.2 2 0 0 2 2 2 2 Cation transport protein CN_hydrolase PF00795.17 KUM64749.1 - 2.8e-28 98.5 0.0 3.5e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ADH_N PF08240.7 KUM64750.1 - 5.4e-06 26.1 0.0 3.9e-05 23.3 0.0 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM64750.1 - 8.9e-05 22.0 0.1 0.00015 21.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Dynamin_M PF01031.15 KUM64751.1 - 1.2e-105 352.4 0.2 1.2e-105 352.4 0.2 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 KUM64751.1 - 3.7e-56 189.5 0.1 7.9e-56 188.4 0.1 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KUM64751.1 - 4.7e-30 103.3 4.4 4.7e-30 103.3 3.0 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KUM64751.1 - 5e-05 23.2 0.3 0.00048 20.0 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KUM64751.1 - 0.0085 16.5 0.0 0.051 14.0 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein WD40 PF00400.27 KUM64756.1 - 2.1e-32 109.8 14.1 2.7e-07 30.2 0.3 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat CLTH PF10607.4 KUM64756.1 - 4e-05 23.3 0.2 6.8e-05 22.5 0.2 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain IKI3 PF04762.7 KUM64756.1 - 0.015 13.1 1.5 0.11 10.3 0.0 2.7 3 1 0 3 3 3 0 IKI3 family PD40 PF07676.7 KUM64756.1 - 0.065 12.9 0.1 54 3.6 0.0 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF4221 PF13970.1 KUM64756.1 - 0.13 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4221) DUF3449 PF11931.3 KUM64757.1 - 4.7e-71 238.3 0.1 1.3e-70 236.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 KUM64757.1 - 1.8e-15 56.1 0.6 3.7e-15 55.1 0.4 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 KUM64757.1 - 9e-08 32.0 5.0 9.5e-06 25.6 1.0 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KUM64757.1 - 3.7e-06 26.9 5.4 1.3e-05 25.1 0.6 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KUM64757.1 - 0.0018 18.3 1.9 0.027 14.5 0.1 2.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Myb_CC_LHEQLE PF14379.1 KUM64757.1 - 0.37 10.3 5.6 24 4.5 2.7 3.4 2 1 0 2 2 2 0 MYB-CC type transfactor, LHEQLE motif zf-C4H2 PF10146.4 KUM64757.1 - 2.3 8.1 6.9 0.087 12.8 0.2 2.0 2 0 0 2 2 2 0 Zinc finger-containing protein DEAD PF00270.24 KUM64758.1 - 1e-39 135.7 0.3 2.6e-39 134.4 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM64758.1 - 1.6e-29 101.5 0.2 3.3e-29 100.5 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KUM64758.1 - 0.0047 16.6 0.2 0.012 15.3 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 KUM64758.1 - 0.012 15.4 0.2 0.025 14.4 0.1 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KUM64758.1 - 0.037 13.6 0.6 0.086 12.4 0.4 1.6 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 KUM64758.1 - 0.046 13.4 0.5 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_22 PF13401.1 KUM64758.1 - 0.12 12.4 0.6 0.54 10.3 0.4 2.0 1 1 0 1 1 1 0 AAA domain Ras PF00071.17 KUM64759.1 - 9.8e-42 142.0 0.0 1.3e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KUM64759.1 - 6.9e-12 45.9 0.0 1.7e-11 44.6 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 KUM64759.1 - 0.0052 16.9 0.0 0.032 14.3 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 KUM64759.1 - 0.016 15.1 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KUM64759.1 - 0.017 14.3 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KUM64759.1 - 0.02 14.8 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase IstB_IS21 PF01695.12 KUM64759.1 - 0.054 12.8 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.7 KUM64759.1 - 0.091 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 KUM64759.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Hemerythrin PF01814.18 KUM64762.1 - 4.6e-17 62.4 0.1 5.8e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain AAA_27 PF13514.1 KUM64762.1 - 0.077 10.6 2.0 0.09 10.4 1.4 1.0 1 0 0 1 1 1 0 AAA domain Inhibitor_I9 PF05922.11 KUM64762.1 - 0.14 12.7 2.5 0.33 11.5 1.7 1.8 1 1 0 1 1 1 0 Peptidase inhibitor I9 KMP11 PF03037.11 KUM64762.1 - 0.22 12.1 2.6 0.19 12.3 0.5 1.9 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 DUF2361 PF10153.4 KUM64762.1 - 1.1 9.4 4.3 7.6 6.7 0.1 2.5 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2361) A_deaminase PF00962.17 KUM64763.1 - 1.2e-43 149.3 0.0 1.6e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase ATP-synt_ab PF00006.20 KUM64764.1 - 2.8e-114 379.9 0.0 3.9e-114 379.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KUM64764.1 - 5.4e-18 65.5 0.6 9.4e-18 64.7 0.4 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KUM64764.1 - 1e-11 44.8 3.4 1.4e-09 37.9 0.2 2.6 2 0 0 2 2 2 2 ATP synthase alpha/beta family, beta-barrel domain SCAN PF02023.12 KUM64765.1 - 0.0078 15.6 0.1 0.17 11.3 0.0 2.5 2 0 0 2 2 2 1 SCAN domain NAC PF01849.13 KUM64766.1 - 6.6e-24 83.1 0.0 6.4e-22 76.8 0.0 2.2 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 KUM64766.1 - 0.00013 21.7 0.3 0.00022 20.9 0.2 1.4 1 0 0 1 1 1 1 UBA/TS-N domain NESP55 PF06390.7 KUM64766.1 - 0.0056 16.0 4.4 0.0056 16.0 3.0 1.9 2 0 0 2 2 2 1 Neuroendocrine-specific golgi protein P55 (NESP55) CENP-B_dimeris PF09026.5 KUM64766.1 - 0.015 15.4 3.9 4.7 7.5 3.0 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CDC45 PF02724.9 KUM64766.1 - 1.4 6.8 9.0 0.049 11.6 2.1 1.5 2 0 0 2 2 2 0 CDC45-like protein SpoIIIAH PF12685.2 KUM64766.1 - 6.6 6.1 12.2 1 8.8 5.6 1.6 2 0 0 2 2 2 0 SpoIIIAH-like protein Ribosomal_L14e PF01929.12 KUM64767.1 - 1.4e-22 79.8 0.1 2.4e-22 79.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 KUM64767.1 - 5.7e-07 29.0 0.2 1.1e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 KOW motif YIF1 PF03878.10 KUM64768.1 - 2.1e-74 249.6 3.4 2.6e-74 249.3 2.3 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 KUM64768.1 - 6.6e-05 22.4 6.3 6.6e-05 22.4 4.4 1.5 2 0 0 2 2 2 1 Yip1 domain Chromate_transp PF02417.10 KUM64768.1 - 0.24 11.0 5.0 0.42 10.1 3.5 1.4 1 0 0 1 1 1 0 Chromate transporter SRP-alpha_N PF04086.8 KUM64769.1 - 9.7e-81 271.2 0.0 1.3e-80 270.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 KUM64769.1 - 1.4e-50 171.4 0.0 2.6e-50 170.5 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 KUM64769.1 - 1e-07 31.9 0.0 3.9e-07 30.0 0.0 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 KUM64769.1 - 4.5e-07 28.9 0.0 8.6e-07 27.9 0.0 1.4 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 KUM64769.1 - 9.1e-06 25.2 0.0 2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.1 KUM64769.1 - 0.0026 17.3 0.0 0.0052 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KUM64769.1 - 0.0033 17.1 0.2 0.0098 15.6 0.0 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KUM64769.1 - 0.0084 15.5 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KUM64769.1 - 0.024 14.0 0.0 0.098 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain AAA_16 PF13191.1 KUM64769.1 - 0.026 14.4 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KUM64769.1 - 0.043 13.9 0.0 0.24 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.13 KUM64769.1 - 0.044 12.9 0.0 0.083 12.0 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MMR_HSR1 PF01926.18 KUM64769.1 - 0.046 13.6 0.0 0.24 11.3 0.0 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.22 KUM64769.1 - 0.084 13.1 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Aldedh PF00171.17 KUM64770.1 - 1.1e-119 399.7 0.0 1.4e-119 399.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FAM220 PF15487.1 KUM64771.1 - 1.8 7.8 5.2 15 4.8 0.0 2.2 2 0 0 2 2 2 0 FAM220 family Mt_ATP-synt_D PF05873.7 KUM64773.1 - 4.2e-20 72.0 0.7 5.1e-20 71.7 0.5 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) T2SM_b PF10741.4 KUM64773.1 - 0.01 15.4 0.4 0.047 13.3 0.0 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b E3_UbLigase_R4 PF13764.1 KUM64773.1 - 0.03 12.2 0.2 0.034 12.0 0.1 1.0 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 Tropomyosin PF00261.15 KUM64773.1 - 0.041 12.9 1.9 0.79 8.7 0.0 2.1 2 0 0 2 2 2 0 Tropomyosin DMPK_coil PF08826.5 KUM64773.1 - 0.1 12.5 2.2 0.15 11.9 0.3 2.1 2 0 0 2 2 2 0 DMPK coiled coil domain like HlyD PF00529.15 KUM64773.1 - 0.14 11.4 4.6 0.17 11.1 3.2 1.1 1 0 0 1 1 1 0 HlyD family secretion protein FlaC_arch PF05377.6 KUM64773.1 - 0.14 12.0 2.3 5.6 6.9 0.4 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Tropomyosin_1 PF12718.2 KUM64773.1 - 0.15 11.9 4.9 10 5.9 0.0 2.4 2 1 1 3 3 3 0 Tropomyosin like Spectrin PF00435.16 KUM64773.1 - 0.17 12.1 4.4 1.7 8.9 0.9 2.2 1 1 0 2 2 2 0 Spectrin repeat DUF2408 PF10303.4 KUM64773.1 - 0.19 11.8 1.0 0.28 11.2 0.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) OmpH PF03938.9 KUM64773.1 - 1.1 9.2 7.0 0.92 9.4 3.9 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) GATase_2 PF00310.16 KUM64774.1 - 1.2e-20 73.6 0.0 4.9e-15 55.0 0.0 2.4 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KUM64774.1 - 1.1e-14 54.5 0.0 3.9e-14 52.7 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KUM64774.1 - 1e-12 47.8 0.0 2.1e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 KUM64774.1 - 1.3e-12 47.4 0.1 3.2e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 KUM64774.1 - 1.4e-06 27.2 0.0 2.4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PRTase_2 PF15609.1 KUM64774.1 - 0.036 13.3 0.0 0.098 11.9 0.0 1.7 1 1 0 1 1 1 0 Phosphoribosyl transferase Rsd_AlgQ PF04353.8 KUM64774.1 - 0.11 12.2 0.2 0.28 10.8 0.0 1.7 2 0 0 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ HhH-GPD PF00730.20 KUM64775.1 - 8.9e-08 32.3 0.0 1.6e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KUM64775.1 - 0.011 15.3 0.0 0.046 13.4 0.0 2.2 1 0 0 1 1 1 0 Helix-hairpin-helix motif Sec16_C PF12931.2 KUM64777.1 - 6.2e-102 341.1 0.0 8.5e-102 340.7 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16_N PF12935.2 KUM64777.1 - 1.9e-57 195.0 21.9 1.9e-57 195.0 15.2 4.9 4 1 1 5 5 5 2 Vesicle coat trafficking protein Sec16 N-terminus Sec16 PF12932.2 KUM64777.1 - 1.8e-32 111.7 0.0 3.6e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Ribosomal_L28e PF01778.12 KUM64778.1 - 7.2e-32 110.2 1.0 1.5e-31 109.2 0.7 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.9 KUM64778.1 - 3.6e-24 84.7 11.8 3.6e-24 84.7 8.2 2.4 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.5 KUM64778.1 - 1.3e-06 27.7 12.8 1.6e-06 27.5 8.9 1.1 1 0 0 1 1 1 1 BUD22 CENP-T PF15511.1 KUM64778.1 - 0.02 14.1 14.9 0.028 13.6 10.3 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 KUM64778.1 - 0.059 11.2 27.2 0.083 10.8 18.8 1.1 1 0 0 1 1 1 0 Nop14-like family SGT1 PF07093.6 KUM64778.1 - 0.067 11.5 9.2 0.083 11.2 6.4 1.2 1 0 0 1 1 1 0 SGT1 protein Na_trans_assoc PF06512.8 KUM64778.1 - 0.35 10.7 8.8 0.57 10.0 6.1 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Mpp10 PF04006.7 KUM64778.1 - 1.3 7.2 27.9 7.2 4.8 0.0 2.1 1 1 0 2 2 2 0 Mpp10 protein CDC45 PF02724.9 KUM64778.1 - 1.6 6.6 20.6 4.9 5.0 11.2 2.0 2 0 0 2 2 2 0 CDC45-like protein Stm1_N PF09598.5 KUM64778.1 - 2.2 9.0 14.8 2.4 8.9 5.2 2.4 2 0 0 2 2 2 0 Stm1 TFIIF_alpha PF05793.7 KUM64778.1 - 7.4 4.8 25.3 12 4.1 17.6 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) E1-E2_ATPase PF00122.15 KUM64779.1 - 9.1e-20 70.6 0.0 2e-18 66.2 0.0 2.7 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KUM64779.1 - 7.8e-15 55.8 0.0 1.1e-13 52.1 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KUM64779.1 - 2.3e-09 37.7 0.3 6e-09 36.3 0.2 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KUM64779.1 - 6.1e-07 29.3 0.0 2.1e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KUM64779.1 - 0.0039 16.8 0.0 0.0082 15.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase GAS2 PF02187.12 KUM64780.1 - 0.00021 21.0 0.1 0.00044 19.9 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Hus1 PF04005.7 KUM64782.1 - 2.4e-104 348.3 0.0 2.8e-104 348.1 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Hexokinase_2 PF03727.11 KUM64783.1 - 6.2e-77 258.0 0.0 7.9e-77 257.7 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KUM64783.1 - 1.6e-63 213.7 0.0 3.4e-63 212.7 0.0 1.5 2 0 0 2 2 2 1 Hexokinase RabGAP-TBC PF00566.13 KUM64785.1 - 2.1e-39 135.2 1.3 4e-39 134.3 0.9 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 KUM64785.1 - 1.5e-11 43.9 0.0 1.9e-07 30.5 0.0 3.2 2 1 0 2 2 2 2 Domain of unknown function (DUF3548) dCMP_cyt_deam_1 PF00383.17 KUM64786.1 - 4.2e-07 29.5 0.0 5.6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 KUM64786.1 - 0.037 13.4 0.1 4.4 6.6 0.0 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases E1-E2_ATPase PF00122.15 KUM64787.1 - 5.3e-63 212.1 1.4 1e-62 211.1 1.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KUM64787.1 - 1.7e-33 115.7 9.1 1.7e-33 115.7 6.3 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KUM64787.1 - 2e-29 103.5 0.0 1.1e-27 97.9 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KUM64787.1 - 3.1e-18 65.0 0.0 7.7e-18 63.7 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KUM64787.1 - 2.5e-15 56.2 0.0 4.8e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KUM64787.1 - 9.3e-12 45.5 0.0 2.6e-11 44.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DctM PF06808.7 KUM64787.1 - 0.00021 19.9 7.4 0.00038 19.1 0.3 2.9 3 0 0 3 3 3 1 DctM-like transporters Hydrolase_3 PF08282.7 KUM64787.1 - 0.00058 19.5 0.2 0.012 15.2 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CBP4 PF07960.6 KUM64787.1 - 0.067 12.8 0.3 0.14 11.7 0.2 1.4 1 0 0 1 1 1 0 CBP4 DNA_methylase PF00145.12 KUM64788.1 - 6.3e-40 137.3 0.0 1.4e-27 96.7 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase MTS PF05175.9 KUM64788.1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 KUM64788.1 - 0.2 10.7 0.0 0.33 10.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MmgE_PrpD PF03972.9 KUM64789.1 - 1.3e-149 498.2 0.0 1.4e-149 498.0 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Glyco_hydro_28 PF00295.12 KUM64790.1 - 3.5e-54 183.9 15.7 4.4e-54 183.6 10.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectinesterase PF01095.14 KUM64791.1 - 1.4e-50 171.5 4.5 1.9e-50 171.1 3.1 1.1 1 0 0 1 1 1 1 Pectinesterase Fig1 PF12351.3 KUM64793.1 - 1.5e-49 168.3 6.1 1.5e-49 168.3 4.2 1.4 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 CorA PF01544.13 KUM64794.1 - 4.5e-10 39.0 3.2 4.5e-10 39.0 2.2 2.9 4 0 0 4 4 4 1 CorA-like Mg2+ transporter protein IFT57 PF10498.4 KUM64794.1 - 0.082 11.6 5.7 0.025 13.3 2.1 1.4 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Nucleoplasmin PF03066.10 KUM64794.1 - 0.6 9.6 3.5 2 7.9 2.5 1.7 2 0 0 2 2 2 0 Nucleoplasmin Abhydrolase_3 PF07859.8 KUM64796.1 - 1.3e-36 126.1 0.0 1.8e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KUM64796.1 - 8.6e-06 24.7 0.0 0.00013 20.8 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KUM64796.1 - 0.00023 20.9 0.0 0.00036 20.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KUM64796.1 - 0.0012 18.1 0.0 0.002 17.3 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.7 KUM64796.1 - 0.0015 17.1 0.0 0.0024 16.4 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 KUM64796.1 - 0.0033 16.8 0.0 0.0052 16.2 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.13 KUM64796.1 - 0.008 15.4 0.1 0.03 13.6 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family G0-G1_switch_2 PF15103.1 KUM64797.1 - 0.0083 16.3 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 G0/G1 switch protein 2 Meckelin PF09773.4 KUM64797.1 - 0.021 12.6 0.2 0.029 12.1 0.1 1.1 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) DUF2157 PF09925.4 KUM64797.1 - 0.33 10.5 10.1 0.55 9.8 7.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF4389 PF14333.1 KUM64797.1 - 0.8 9.4 4.1 0.54 10.0 0.2 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4389) DUF202 PF02656.10 KUM64797.1 - 1.6 9.0 7.6 1.7 8.9 3.6 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Vma12 PF11712.3 KUM64797.1 - 7.6 6.2 5.9 1.4 8.5 1.5 1.7 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase ADH_N PF08240.7 KUM64798.1 - 5e-11 42.3 0.3 4e-10 39.4 0.2 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM64798.1 - 2.3e-09 36.9 0.2 3.7e-09 36.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Mso1_Sec1_bdg PF14475.1 KUM64799.1 - 2.8e-10 39.4 0.0 4.5e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Rieske PF00355.21 KUM64801.1 - 4.9e-18 64.4 0.0 8.6e-18 63.7 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.14 KUM64801.1 - 1.9e-07 30.9 0.2 0.00019 21.1 0.0 2.6 2 1 1 3 3 3 2 Ring hydroxylating alpha subunit (catalytic domain) Porin_OmpL1 PF11389.3 KUM64801.1 - 0.063 12.3 0.0 0.095 11.7 0.0 1.2 1 0 0 1 1 1 0 Leptospira porin protein OmpL1 Ring_hydroxyl_A PF00848.14 KUM64802.1 - 1.5e-30 106.4 1.0 2.2e-28 99.3 1.2 2.8 2 1 0 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) Polysacc_lyase PF14099.1 KUM64803.1 - 1.2e-51 175.4 7.8 1.4e-51 175.3 5.4 1.0 1 0 0 1 1 1 1 Polysaccharide lyase DUF1080 PF06439.6 KUM64803.1 - 0.00027 20.8 5.3 0.00053 19.9 3.6 1.5 1 1 0 1 1 1 1 Domain of Unknown Function (DUF1080) Laminin_G_2 PF02210.19 KUM64803.1 - 0.0053 16.8 0.0 0.0072 16.3 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Ago_hook PF10427.4 KUM64803.1 - 0.44 10.5 2.9 1.5 8.8 0.0 2.7 3 0 0 3 3 3 0 Argonaute hook Ank_2 PF12796.2 KUM64804.1 - 0.0025 18.1 0.0 0.036 14.3 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KUM64804.1 - 0.023 14.9 0.5 4.2 7.9 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeat Ribosomal_L11_N PF03946.9 KUM64804.1 - 0.11 11.9 0.0 0.52 9.8 0.0 2.0 1 1 1 2 2 2 0 Ribosomal protein L11, N-terminal domain HATPase_c PF02518.21 KUM64805.1 - 0.044 13.5 0.0 0.046 13.4 0.0 1.1 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase F-box PF00646.28 KUM64806.1 - 0.032 13.9 0.1 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 F-box domain DUF2700 PF10912.3 KUM64807.1 - 0.054 13.4 0.2 0.055 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2700) MFS_1 PF07690.11 KUM64808.1 - 2.2e-36 125.3 20.7 2e-27 95.8 0.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM64808.1 - 1.2e-09 37.2 14.9 1.7e-09 36.7 1.3 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 KUM64808.1 - 0.00045 18.7 2.5 0.00045 18.7 1.7 4.0 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 KUM64808.1 - 0.006 16.3 2.5 0.078 12.7 0.0 3.8 4 0 0 4 4 4 1 MFS_1 like family DUF1664 PF07889.7 KUM64811.1 - 0.46 10.2 0.7 9 6.1 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) BSD PF03909.12 KUM64814.1 - 3.8e-16 58.5 1.4 9.2e-16 57.3 1.0 1.7 1 0 0 1 1 1 1 BSD domain DUF1759 PF03564.10 KUM64814.1 - 0.045 13.5 0.1 0.38 10.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) KH_1 PF00013.24 KUM64817.1 - 9.3e-42 140.5 2.0 4.9e-16 58.1 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KUM64817.1 - 1.4e-30 104.3 10.2 1.4e-10 40.5 1.3 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KUM64817.1 - 2.8e-12 45.9 2.7 0.0041 16.6 0.0 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KUM64817.1 - 5.1e-05 22.8 0.1 1.7 8.3 0.0 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 KUM64817.1 - 0.0029 17.3 5.8 1.4 8.7 0.2 3.2 3 0 0 3 3 3 2 NusA-like KH domain Proteasome PF00227.21 KUM64818.1 - 3.7e-44 150.3 0.1 4.8e-44 149.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 KUM64818.1 - 2.1e-13 49.2 0.4 4.9e-13 48.0 0.3 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Methyltransf_23 PF13489.1 KUM64819.1 - 7.7e-19 67.9 0.0 2.3e-18 66.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM64819.1 - 4.5e-08 33.6 0.0 9e-07 29.4 0.0 2.8 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM64819.1 - 2.1e-07 30.6 0.0 1.3e-06 28.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM64819.1 - 4.7e-06 26.9 0.0 1.9e-05 25.0 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM64819.1 - 3.1e-05 24.3 0.0 0.00018 21.9 0.0 2.4 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KUM64819.1 - 0.0058 16.6 0.0 0.11 12.5 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 KUM64819.1 - 0.0078 15.2 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 KUM64819.1 - 0.0097 16.2 0.0 0.24 11.7 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain PrmA PF06325.8 KUM64819.1 - 0.013 14.5 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 KUM64819.1 - 0.054 12.9 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 KUM64819.1 - 0.1 11.7 0.0 0.28 10.2 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.14 KUM64819.1 - 0.3 10.6 0.0 0.55 9.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 KUM64820.1 - 6.2e-19 68.1 0.1 8.9e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KUM64820.1 - 7.5e-05 22.1 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DUF4470 PF14737.1 KUM64821.1 - 9e-20 70.2 0.0 1.6e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) KAR9 PF08580.5 KUM64823.1 - 1.5e-141 472.9 4.6 1.5e-141 472.9 3.2 2.1 2 0 0 2 2 2 1 Yeast cortical protein KAR9 DUF2746 PF10874.3 KUM64823.1 - 0.026 14.7 1.1 6.2 7.0 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2746) DNA_photolyase PF00875.13 KUM64823.1 - 0.037 13.7 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 DNA photolyase NPV_P10 PF05531.7 KUM64823.1 - 0.19 11.9 5.3 0.16 12.2 0.6 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Acetyltransf_1 PF00583.19 KUM64824.1 - 5.8e-07 29.4 0.0 8.2e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 KUM64824.1 - 5.9e-06 26.4 0.0 7.9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KUM64824.1 - 0.0004 20.2 0.0 0.00061 19.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KUM64824.1 - 0.00051 20.0 0.0 0.00074 19.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KUM64824.1 - 0.0052 16.9 0.0 0.0082 16.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KUM64824.1 - 0.0082 16.2 0.0 0.014 15.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KUM64824.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Complex1_LYR PF05347.10 KUM64825.1 - 3e-08 33.3 0.0 5.7e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KUM64825.1 - 8.2e-07 29.1 0.0 1.5e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KUM64825.1 - 6.1e-05 23.4 0.1 0.00011 22.6 0.1 1.4 1 0 0 1 1 1 1 Complex1_LYR-like MBOAT PF03062.14 KUM64827.1 - 1.8e-43 148.9 8.0 1.8e-43 148.9 5.5 1.5 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Cortexin PF11057.3 KUM64827.1 - 0.06 12.9 1.4 2 8.0 0.0 3.0 3 0 0 3 3 3 0 Cortexin of kidney Acylphosphatase PF00708.13 KUM64828.1 - 1.8e-24 85.6 0.2 2.2e-24 85.3 0.1 1.1 1 0 0 1 1 1 1 Acylphosphatase AOX PF01786.12 KUM64829.1 - 3.4e-92 307.5 0.0 4.1e-92 307.2 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase ISK_Channel PF02060.10 KUM64829.1 - 0.073 12.6 0.2 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 Slow voltage-gated potassium channel AFP PF02420.10 KUM64831.1 - 3e-06 26.6 1.0 3.6 8.0 0.0 4.3 4 0 0 4 4 4 4 Insect antifreeze protein repeat zf-CCHC PF00098.18 KUM64831.1 - 0.088 12.7 8.4 2.8 8.0 0.1 4.2 4 0 0 4 4 4 0 Zinc knuckle DUF1576 PF07613.6 KUM64833.1 - 0.006 16.1 0.1 15 5.0 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1576) Phage-MuB_C PF09077.6 KUM64833.1 - 0.011 15.4 0.2 7 6.4 0.0 2.9 1 1 2 3 3 3 0 Mu B transposition protein, C terminal Oleosin PF01277.12 KUM64833.1 - 0.015 14.8 9.6 2.8 7.5 0.1 3.1 3 0 0 3 3 3 0 Oleosin DUF3389 PF11869.3 KUM64833.1 - 0.062 13.1 2.5 22 5.0 0.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3389) DDHD PF02862.12 KUM64835.1 - 0.0014 18.4 9.3 0.0016 18.2 6.4 1.1 1 0 0 1 1 1 1 DDHD domain U79_P34 PF03064.11 KUM64835.1 - 0.0017 17.9 12.3 0.0019 17.7 8.5 1.1 1 0 0 1 1 1 1 HSV U79 / HCMV P34 DUF1510 PF07423.6 KUM64835.1 - 0.0019 17.6 15.3 0.0022 17.3 10.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Caldesmon PF02029.10 KUM64835.1 - 0.0053 15.2 22.8 0.0067 14.9 15.8 1.0 1 0 0 1 1 1 1 Caldesmon SET PF00856.23 KUM64835.1 - 0.0082 16.4 2.6 0.0097 16.2 1.8 1.1 1 0 0 1 1 1 1 SET domain Tim54 PF11711.3 KUM64835.1 - 0.017 13.7 9.5 0.019 13.5 6.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4604 PF15377.1 KUM64835.1 - 0.021 15.0 23.2 0.028 14.6 16.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) FGF-BP1 PF06473.7 KUM64835.1 - 0.024 14.2 14.3 0.03 13.9 9.9 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Atrophin-1 PF03154.10 KUM64835.1 - 0.025 12.7 8.3 0.026 12.6 5.7 1.1 1 0 0 1 1 1 0 Atrophin-1 family B12D PF06522.6 KUM64835.1 - 0.027 14.1 8.0 0.13 11.9 5.6 2.0 1 1 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Bud13 PF09736.4 KUM64835.1 - 0.03 14.6 17.9 0.034 14.4 12.4 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF2215 PF10225.4 KUM64835.1 - 0.032 13.6 4.6 0.035 13.5 3.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Vfa1 PF08432.5 KUM64835.1 - 0.039 13.9 23.0 0.046 13.7 15.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 HSP90 PF00183.13 KUM64835.1 - 0.04 12.3 19.1 0.045 12.1 13.2 1.0 1 0 0 1 1 1 0 Hsp90 protein Folate_carrier PF01770.13 KUM64835.1 - 0.044 12.2 6.8 0.057 11.9 4.7 1.1 1 0 0 1 1 1 0 Reduced folate carrier Kei1 PF08552.6 KUM64835.1 - 0.047 13.3 1.9 0.056 13.0 1.3 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Tom37_C PF11801.3 KUM64835.1 - 0.047 13.5 9.0 0.055 13.3 6.2 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain Mem_trans PF03547.13 KUM64835.1 - 0.048 11.9 5.0 0.05 11.8 3.5 1.0 1 0 0 1 1 1 0 Membrane transport protein GAGA_bind PF06217.7 KUM64835.1 - 0.069 13.1 14.3 0.077 12.9 9.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 KUM64835.1 - 0.084 12.7 15.0 0.095 12.5 10.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Protocadherin PF08374.6 KUM64835.1 - 0.089 12.4 11.3 0.11 12.0 7.8 1.3 1 0 0 1 1 1 0 Protocadherin GOLD_2 PF13897.1 KUM64835.1 - 0.09 13.0 3.7 0.12 12.6 2.5 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking FAM60A PF15396.1 KUM64835.1 - 0.095 12.4 14.7 0.12 12.1 10.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A TATR PF03430.8 KUM64835.1 - 0.096 11.3 14.1 0.1 11.1 9.8 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DUF3513 PF12026.3 KUM64835.1 - 0.099 12.1 12.0 0.12 11.8 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) Serinc PF03348.10 KUM64835.1 - 0.1 11.2 6.5 0.12 11.0 4.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) AAA_21 PF13304.1 KUM64835.1 - 0.16 11.9 2.4 0.17 11.7 1.7 1.0 1 0 0 1 1 1 0 AAA domain DUF2217 PF10265.4 KUM64835.1 - 0.18 10.4 7.2 0.18 10.5 5.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Tfb4 PF03850.9 KUM64835.1 - 0.21 10.7 7.4 0.27 10.4 5.1 1.0 1 0 0 1 1 1 0 Transcription factor Tfb4 Y_phosphatase3 PF13350.1 KUM64835.1 - 0.24 11.6 3.4 0.29 11.3 2.4 1.1 1 0 0 1 1 1 0 Tyrosine phosphatase family Gag_spuma PF03276.9 KUM64835.1 - 0.26 9.5 3.7 0.27 9.5 2.6 1.1 1 0 0 1 1 1 0 Spumavirus gag protein RNase_H2-Ydr279 PF09468.5 KUM64835.1 - 0.26 10.4 22.4 0.37 9.9 15.5 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) STT3 PF02516.9 KUM64835.1 - 0.27 10.1 0.8 0.3 9.9 0.6 1.0 1 0 0 1 1 1 0 Oligosaccharyl transferase STT3 subunit Glyco_transf_15 PF01793.11 KUM64835.1 - 0.33 9.8 9.7 0.39 9.5 6.7 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase UPF0560 PF10577.4 KUM64835.1 - 0.37 8.9 10.1 0.4 8.9 7.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 FAM176 PF14851.1 KUM64835.1 - 0.38 10.4 6.7 0.48 10.1 4.6 1.2 1 0 0 1 1 1 0 FAM176 family Ycf1 PF05758.7 KUM64835.1 - 0.39 8.3 15.3 0.41 8.3 10.6 1.0 1 0 0 1 1 1 0 Ycf1 DUF106 PF01956.11 KUM64835.1 - 0.42 10.1 9.2 0.49 9.9 6.4 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 FHIPEP PF00771.15 KUM64835.1 - 0.42 8.8 3.7 0.55 8.5 2.6 1.3 1 0 0 1 1 1 0 FHIPEP family DDRGK PF09756.4 KUM64835.1 - 0.45 9.8 28.5 0.55 9.6 19.8 1.1 1 0 0 1 1 1 0 DDRGK domain SOBP PF15279.1 KUM64835.1 - 0.45 10.8 12.2 0.49 10.7 8.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Sec62 PF03839.11 KUM64835.1 - 0.45 9.8 19.2 0.54 9.6 13.3 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 LicD PF04991.8 KUM64835.1 - 0.49 10.4 11.4 0.58 10.2 7.9 1.1 1 0 0 1 1 1 0 LicD family PEHE PF15275.1 KUM64835.1 - 0.54 10.7 10.7 0.74 10.2 7.4 1.2 1 0 0 1 1 1 0 PEHE domain DUF3807 PF12720.2 KUM64835.1 - 0.57 10.3 18.9 0.7 10.0 13.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) RBP_receptor PF14752.1 KUM64835.1 - 0.6 8.3 4.7 0.66 8.2 3.2 1.1 1 0 0 1 1 1 0 Retinol binding protein receptor Pex16 PF08610.5 KUM64835.1 - 0.61 9.0 8.9 0.77 8.6 6.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Dynamin_N PF00350.18 KUM64835.1 - 0.66 9.7 6.5 0.73 9.6 4.5 1.2 1 0 0 1 1 1 0 Dynamin family SspB PF04386.8 KUM64835.1 - 0.87 9.1 7.3 1.3 8.6 5.1 1.4 1 0 0 1 1 1 0 Stringent starvation protein B DUF2828 PF11443.3 KUM64835.1 - 0.9 7.6 12.0 1 7.4 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Band_3_cyto PF07565.8 KUM64835.1 - 0.98 8.8 8.0 1.1 8.7 5.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF3987 PF13148.1 KUM64835.1 - 1 7.8 12.7 1.1 7.7 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) RNA_polI_A34 PF08208.6 KUM64835.1 - 1 9.0 34.9 1.3 8.6 24.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 OATP PF03137.15 KUM64835.1 - 1 7.3 5.9 1.1 7.1 4.1 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Rtf2 PF04641.7 KUM64835.1 - 1 8.4 22.2 1.3 8.1 15.4 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger PDCD2_C PF04194.8 KUM64835.1 - 1.1 8.8 9.9 1.3 8.5 6.9 1.2 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain DUF3408 PF11888.3 KUM64835.1 - 1.2 9.0 16.1 1.6 8.6 11.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Neur_chan_memb PF02932.11 KUM64835.1 - 1.3 8.9 9.9 1.5 8.6 6.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nucleoside_tran PF01733.13 KUM64835.1 - 1.3 8.1 3.6 1.6 7.8 2.5 1.1 1 0 0 1 1 1 0 Nucleoside transporter GCD14 PF08704.5 KUM64835.1 - 1.4 8.3 7.7 1.5 8.2 5.3 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF4569 PF15133.1 KUM64835.1 - 1.4 8.2 11.2 1.7 7.9 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Hom_end_hint PF05203.11 KUM64835.1 - 1.5 8.5 9.1 1.6 8.4 6.3 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint SID-1_RNA_chan PF13965.1 KUM64835.1 - 1.5 6.8 5.2 1.5 6.8 3.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Bap31 PF05529.7 KUM64835.1 - 1.9 7.9 13.9 2.6 7.4 9.7 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like NARP1 PF12569.3 KUM64835.1 - 1.9 7.1 24.7 2.3 6.8 17.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Otopetrin PF03189.8 KUM64835.1 - 1.9 7.3 7.1 2.2 7.1 4.9 1.1 1 0 0 1 1 1 0 Otopetrin Zip PF02535.17 KUM64835.1 - 2.3 7.1 6.5 2.6 6.9 4.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RP-C_C PF11800.3 KUM64835.1 - 2.5 7.7 8.1 2.8 7.5 5.6 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Pex24p PF06398.6 KUM64835.1 - 2.6 6.7 7.2 3 6.5 5.0 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Cellulose_synt PF03552.9 KUM64835.1 - 2.6 6.2 6.7 2.5 6.2 4.6 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF2413 PF10310.4 KUM64835.1 - 3 6.5 21.2 3.7 6.2 14.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Peptidase_U57 PF05582.7 KUM64835.1 - 3.6 6.4 12.3 4.6 6.1 8.5 1.1 1 0 0 1 1 1 0 YabG peptidase U57 MIP-T3 PF10243.4 KUM64835.1 - 4.2 5.7 35.5 5.3 5.4 24.6 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 HSP70 PF00012.15 KUM64835.1 - 4.4 5.1 13.2 4.3 5.1 9.1 1.0 1 0 0 1 1 1 0 Hsp70 protein Paramyxo_ncap PF00973.14 KUM64835.1 - 5.6 5.5 11.6 6.2 5.3 8.1 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein AAA_11 PF13086.1 KUM64835.1 - 5.8 6.4 13.4 7.4 6.0 9.3 1.2 1 0 0 1 1 1 0 AAA domain RNA_pol_Rpb1_5 PF04998.12 KUM64835.1 - 7.1 5.8 12.0 7.6 5.7 8.3 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 NPR3 PF03666.8 KUM64835.1 - 7.4 4.9 21.1 9.4 4.6 14.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Abhydrolase_6 PF12697.2 KUM64837.1 - 2.8e-14 53.5 0.0 1.2e-13 51.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM64837.1 - 3.7e-10 39.7 0.0 4.7e-09 36.1 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM64837.1 - 6.3e-10 38.9 0.0 1.5e-09 37.7 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KUM64837.1 - 0.0036 16.5 0.0 0.017 14.3 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 KUM64837.1 - 0.0076 15.7 0.0 0.013 14.9 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.3 KUM64837.1 - 0.0099 15.7 0.0 0.05 13.4 0.0 2.1 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S15 PF02129.13 KUM64837.1 - 0.15 11.4 0.0 1.3 8.3 0.0 2.1 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) TRI12 PF06609.8 KUM64838.1 - 7.5e-13 47.5 14.9 1e-12 47.1 10.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KUM64838.1 - 1.7e-12 46.7 30.1 6.6e-12 44.8 19.8 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF21 PF01595.15 KUM64838.1 - 8.1 5.6 12.2 7.7 5.7 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function DUF21 Dopey_N PF04118.9 KUM64839.1 - 5.1e-120 399.9 0.0 1.9e-119 398.0 0.0 1.9 2 0 0 2 2 2 1 Dopey, N-terminal Mon1 PF03164.9 KUM64840.1 - 5.7e-120 400.6 0.0 6.8e-120 400.4 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 DEAD PF00270.24 KUM64841.1 - 6.4e-23 81.0 0.0 2.2e-21 76.0 0.0 2.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM64841.1 - 2.6e-18 65.6 0.0 3.1e-16 58.9 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RQC PF09382.5 KUM64841.1 - 2e-16 59.5 0.0 4.6e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 RQC domain HRDC PF00570.18 KUM64841.1 - 4e-07 29.6 0.0 1.1e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.10 KUM64841.1 - 0.0046 16.8 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pyridoxal_deC PF00282.14 KUM64842.1 - 1.8e-27 95.7 0.0 2.6e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KUM64842.1 - 7.6e-06 25.2 0.0 1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KUM64842.1 - 0.012 14.3 0.0 0.021 13.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Aminotran_1_2 PF00155.16 KUM64842.1 - 0.014 14.3 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II DUF4110 PF13422.1 KUM64843.1 - 9.3e-29 99.1 3.6 9.3e-29 99.1 2.5 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.1 KUM64843.1 - 1.1e-27 95.5 16.5 8.4e-09 35.3 0.1 6.6 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.1 KUM64843.1 - 2.5e-23 81.5 20.2 1.5e-06 27.8 0.0 6.3 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KUM64843.1 - 9.2e-15 54.2 6.4 1.7e-05 24.6 0.1 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 KUM64843.1 - 1.2e-14 53.3 6.3 8e-05 22.2 0.0 5.9 5 1 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 KUM64843.1 - 3.4e-14 52.3 6.7 0.00053 20.0 0.2 5.3 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 KUM64843.1 - 1.1e-11 44.0 0.9 1.1e-05 24.9 0.1 5.2 5 0 0 5 5 5 1 Kelch motif Bd3614-deam PF14439.1 KUM64843.1 - 3 7.7 6.1 33 4.3 0.0 2.4 2 0 0 2 2 2 0 Bd3614-like deaminase DivIC PF04977.10 KUM64844.1 - 0.048 13.1 0.2 0.059 12.8 0.1 1.2 1 0 0 1 1 1 0 Septum formation initiator BLOC1_2 PF10046.4 KUM64844.1 - 0.049 13.7 0.2 0.061 13.4 0.2 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Hpt PF01627.18 KUM64845.1 - 0.022 14.7 0.1 0.71 9.9 0.0 3.0 3 0 0 3 3 3 0 Hpt domain MazG PF03819.12 KUM64845.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain WGG PF10273.4 KUM64847.1 - 1.4e-30 105.2 0.7 2.9e-30 104.1 0.5 1.6 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 DUF1626 PF07788.6 KUM64847.1 - 0.0061 16.3 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1626) RRP7 PF12923.2 KUM64847.1 - 0.53 10.3 6.0 2.2 8.2 0.0 2.3 2 1 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) APH PF01636.18 KUM64851.1 - 1.1e-10 41.7 0.0 2.2e-10 40.6 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KUM64851.1 - 9.3e-08 31.8 0.1 2.4e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 KUM64851.1 - 0.0009 17.9 0.0 0.0023 16.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 KUM64851.1 - 0.0078 15.3 0.2 0.02 14.0 0.0 1.6 2 0 0 2 2 2 1 Ecdysteroid kinase Pkinase PF00069.20 KUM64851.1 - 0.012 14.7 0.1 2 7.4 0.0 2.4 2 1 0 2 2 2 0 Protein kinase domain Pox_ser-thr_kin PF05445.6 KUM64851.1 - 0.022 13.5 0.0 0.041 12.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF3297 PF11730.3 KUM64851.1 - 0.06 13.0 0.5 0.11 12.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3297) Ferric_reduct PF01794.14 KUM64853.1 - 2.2e-15 56.8 8.6 2.2e-15 56.8 5.9 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KUM64853.1 - 1.5e-12 47.6 0.0 2.7e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KUM64853.1 - 1.8e-12 47.0 0.0 4.4e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain SK_channel PF03530.9 KUM64853.1 - 0.013 15.3 0.0 0.044 13.6 0.0 1.9 1 0 0 1 1 1 0 Calcium-activated SK potassium channel Methyltransf_2 PF00891.13 KUM64854.1 - 1e-32 113.2 0.0 1.9e-32 112.3 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KUM64854.1 - 1.9e-07 31.6 0.0 4.3e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM64854.1 - 2e-07 31.4 0.0 4.1e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM64854.1 - 1.5e-05 24.6 0.0 2.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM64854.1 - 4.1e-05 23.3 0.0 7.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KUM64854.1 - 0.00066 19.1 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.13 KUM64854.1 - 0.0011 18.3 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_26 PF13659.1 KUM64854.1 - 0.011 15.7 0.2 0.041 13.9 0.1 2.0 2 1 0 2 2 2 0 Methyltransferase domain Ran-binding PF05508.6 KUM64855.1 - 1.1e-112 375.9 0.2 1.4e-112 375.5 0.1 1.1 1 0 0 1 1 1 1 RanGTP-binding protein GTP_EFTU PF00009.22 KUM64856.1 - 2.1e-39 134.8 0.0 3.5e-39 134.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KUM64856.1 - 2.4e-20 72.5 0.0 6e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KUM64856.1 - 0.00022 21.2 0.0 0.00064 19.7 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KUM64856.1 - 0.0068 16.3 0.0 0.017 15.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 KUM64856.1 - 0.011 14.4 1.4 0.024 13.3 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit Mfp-3 PF04202.8 KUM64856.1 - 5.3 7.3 11.4 14 5.9 7.9 1.8 1 0 0 1 1 1 0 Foot protein 3 BTB PF00651.26 KUM64857.1 - 7.5e-11 42.0 0.0 1.2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Acetyltransf_8 PF13523.1 KUM64858.1 - 3.9e-48 163.1 0.1 5.7e-48 162.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_hydro_12 PF01670.11 KUM64859.1 - 1.2e-34 119.3 0.6 1.2e-34 119.3 0.4 1.7 2 1 1 3 3 3 1 Glycosyl hydrolase family 12 Cyclin_N PF00134.18 KUM64860.1 - 9.2e-12 44.6 0.0 3.3e-11 42.8 0.0 2.0 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.6 KUM64860.1 - 2.6e-10 40.8 0.0 5.4e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Cyclin VWA_3 PF13768.1 KUM64861.1 - 4.8e-28 97.8 0.0 9.9e-28 96.7 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 KUM64861.1 - 5.2e-16 58.4 0.1 1.4e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VIT_2 PF13757.1 KUM64861.1 - 1.6e-12 46.7 0.0 3.6e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 KUM64861.1 - 6.5e-10 39.3 0.0 1e-08 35.4 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 KUM64861.1 - 4.8e-06 26.4 0.0 1.1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 KUM64861.1 - 0.011 14.8 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.4 KUM64861.1 - 0.016 15.0 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 vWA found in TerF C terminus ERG2_Sigma1R PF04622.7 KUM64862.1 - 8.3e-98 325.9 0.6 9.5e-98 325.7 0.4 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein DUF3687 PF12459.3 KUM64862.1 - 0.013 14.6 0.4 0.037 13.2 0.3 1.8 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein BTB PF00651.26 KUM64865.1 - 3.8e-10 39.7 0.0 5.9e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Sec3_C PF09763.4 KUM64867.1 - 6.9e-223 741.7 0.0 1e-222 741.2 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 KUM64867.1 - 5.8e-31 106.2 0.0 1.2e-30 105.2 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.1 KUM64867.1 - 0.0057 16.7 0.1 0.016 15.3 0.1 1.8 1 0 0 1 1 1 1 Sec3 exocyst complex subunit DOCK-C2 PF14429.1 KUM64868.1 - 1.7e-35 122.3 0.0 3.5e-35 121.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 KUM64868.1 - 4.8e-14 52.0 0.1 1e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_1 PF00018.23 KUM64868.1 - 1.2e-05 24.6 0.0 2.5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KUM64868.1 - 2.8e-05 23.6 0.0 0.00022 20.7 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain Ribosomal_S19 PF00203.16 KUM64868.1 - 0.061 12.9 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S19 SH3_2 PF07653.12 KUM64868.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Pox_F16 PF04708.7 KUM64868.1 - 0.19 11.0 0.0 0.46 9.7 0.0 1.6 1 0 0 1 1 1 0 Poxvirus F16 protein CD47 PF04549.9 KUM64868.1 - 0.2 11.6 0.2 0.42 10.5 0.2 1.4 1 0 0 1 1 1 0 CD47 transmembrane region Na_Ca_ex PF01699.19 KUM64869.1 - 4e-46 156.0 26.9 1.4e-23 83.0 7.9 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein IpaC_SipC PF09599.5 KUM64870.1 - 0.37 9.7 4.7 0.41 9.6 2.8 1.4 1 1 0 1 1 1 0 Salmonella-Shigella invasin protein C (IpaC_SipC) FUSC PF04632.7 KUM64870.1 - 2 6.7 5.4 9.4 4.5 2.2 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family MFS_1 PF07690.11 KUM64872.1 - 1.6e-33 115.9 25.3 1.6e-33 115.9 17.6 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM64872.1 - 3.4e-11 42.3 4.7 3.4e-11 42.3 3.3 3.2 2 2 1 3 3 3 2 Sugar (and other) transporter Fungal_trans_2 PF11951.3 KUM64873.1 - 1.9e-06 26.7 0.0 2.3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 KUM64874.1 - 1.9e-20 73.4 0.0 2.8e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM64874.1 - 1.1e-08 35.0 0.0 2.1e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KUM64874.1 - 2.4e-06 27.5 0.0 0.00017 21.4 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KUM64874.1 - 0.00023 20.6 0.1 0.00035 20.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KUM64874.1 - 0.001 19.1 0.1 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KUM64874.1 - 0.034 12.8 0.1 0.05 12.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_25 PF13649.1 KUM64874.1 - 0.034 14.4 0.0 0.07 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Shikimate_DH PF01488.15 KUM64874.1 - 0.044 13.8 0.0 0.068 13.2 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DICT PF10069.4 KUM64874.1 - 0.045 13.2 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 Sensory domain found in DIguanylate Cyclases & Two-component systems DUF1653 PF07866.6 KUM64875.1 - 0.095 12.8 0.1 0.32 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1653) Desulfoferrod_N PF06397.7 KUM64875.1 - 0.17 11.3 0.3 0.73 9.2 0.0 2.2 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain HSP70 PF00012.15 KUM64876.1 - 1e-05 23.6 0.0 1.2e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KUM64876.1 - 0.0035 15.9 0.0 0.0051 15.4 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Terpene_synth_C PF03936.11 KUM64876.1 - 0.0057 15.9 0.4 0.0082 15.3 0.3 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain ApbA PF02558.11 KUM64877.1 - 1.4e-28 99.2 0.0 2e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KUM64877.1 - 4.8e-25 87.9 0.0 7e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ThiF PF00899.16 KUM64877.1 - 0.02 14.7 1.4 0.039 13.7 0.4 1.9 2 0 0 2 2 2 0 ThiF family Amidohydro_2 PF04909.9 KUM64878.1 - 5.3e-31 108.1 0.0 6.9e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 KUM64878.1 - 0.017 14.3 0.0 0.046 12.9 0.0 1.7 2 0 0 2 2 2 0 TatD related DNase eIF-5a PF01287.15 KUM64879.1 - 2e-25 88.5 2.5 3e-25 87.9 1.7 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 KUM64879.1 - 0.0012 18.4 0.2 0.0021 17.6 0.1 1.4 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 KUM64879.1 - 0.021 14.7 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain p12I PF12233.3 KUM64879.1 - 0.031 14.5 2.3 0.049 13.8 1.6 1.2 1 0 0 1 1 1 0 Human adult T cell leukemia/lymphoma virus protein Nitro_FeMo-Co PF02579.12 KUM64879.1 - 0.13 12.4 0.0 0.26 11.3 0.0 1.6 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor Vps52 PF04129.7 KUM64880.1 - 9.7e-119 397.1 0.0 1.3e-118 396.7 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 KUM64880.1 - 2.2e-08 32.7 0.1 3.1e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec3 BicD PF09730.4 KUM64880.1 - 0.0073 14.7 2.4 0.011 14.0 1.7 1.2 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D Exo70 PF03081.10 KUM64880.1 - 0.021 13.5 2.8 0.22 10.2 0.1 3.0 3 0 0 3 3 3 0 Exo70 exocyst complex subunit DUF2552 PF10827.3 KUM64880.1 - 0.027 14.3 0.0 0.067 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2552) Sec8_exocyst PF04048.9 KUM64880.1 - 0.044 13.4 0.5 0.044 13.4 0.3 2.0 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain THOC7 PF05615.8 KUM64880.1 - 0.049 13.9 2.2 0.069 13.4 0.2 2.2 3 0 0 3 3 3 0 Tho complex subunit 7 IncA PF04156.9 KUM64880.1 - 1.1 8.8 8.9 0.083 12.4 1.3 2.5 3 0 0 3 3 3 0 IncA protein Choline_kinase PF01633.15 KUM64881.1 - 1.6e-22 80.1 0.0 2.4e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KUM64881.1 - 0.0076 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family UPF0223 PF05256.7 KUM64881.1 - 0.056 13.5 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0223) ADH_N PF08240.7 KUM64882.1 - 4.8e-35 119.6 2.8 9e-35 118.7 1.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM64882.1 - 1.5e-16 60.1 0.0 2.5e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 KUM64882.1 - 0.0011 18.1 0.9 0.0018 17.4 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 KUM64882.1 - 0.0017 18.5 0.0 0.0036 17.5 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.13 KUM64882.1 - 0.011 15.7 0.0 0.027 14.4 0.0 1.6 1 1 0 1 1 1 0 TrkA-N domain DUF2318 PF10080.4 KUM64882.1 - 0.018 14.7 1.7 6.3 6.6 0.2 3.2 3 0 0 3 3 3 0 Predicted membrane protein (DUF2318) NAD_binding_8 PF13450.1 KUM64882.1 - 0.019 15.0 0.5 0.047 13.7 0.1 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Gp_dh_N PF00044.19 KUM64882.1 - 0.032 14.2 0.1 0.15 12.0 0.1 2.0 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KUM64882.1 - 0.067 13.2 0.1 0.27 11.3 0.1 1.9 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase XdhC_C PF13478.1 KUM64882.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain Pyr_redox PF00070.22 KUM64882.1 - 0.13 12.7 1.0 0.24 11.8 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_18 PF12847.2 KUM64882.1 - 0.13 12.8 0.1 0.44 11.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain FRG1 PF06229.7 KUM64883.1 - 2.7e-57 193.3 0.1 4e-57 192.7 0.0 1.2 1 0 0 1 1 1 1 FRG1-like family Fascin PF06268.8 KUM64883.1 - 0.044 13.8 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Fascin domain Frataxin_Cyay PF01491.11 KUM64883.1 - 0.14 11.9 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 Frataxin-like domain Ham1p_like PF01725.11 KUM64884.1 - 1.2e-49 168.2 0.0 1.4e-49 168.0 0.0 1.0 1 0 0 1 1 1 1 Ham1 family SRP40_C PF05022.7 KUM64885.1 - 3.9e-21 75.3 0.1 1.1e-20 73.9 0.1 1.7 1 0 0 1 1 1 1 SRP40, C-terminal domain P5CR_dimer PF14748.1 KUM64886.1 - 2.1e-20 72.7 1.0 8.9e-20 70.6 0.2 2.2 3 0 0 3 3 3 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KUM64886.1 - 3.4e-13 49.8 1.2 3e-12 46.7 0.6 2.4 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KUM64886.1 - 0.0015 18.3 0.0 0.0036 17.1 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase OCD_Mu_crystall PF02423.10 KUM64887.1 - 1.7e-15 56.6 0.0 7.4e-13 47.9 0.0 3.3 2 1 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 KUM64887.1 - 4.1e-07 30.1 0.0 1.3e-06 28.5 0.0 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF3530 PF12048.3 KUM64887.1 - 0.0045 16.0 0.0 0.0074 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) CcmD PF04995.9 KUM64889.1 - 0.1 12.3 1.5 2 8.1 1.0 2.4 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF1992 PF09350.5 KUM64891.1 - 2.1e-23 81.8 0.2 7.2e-23 80.2 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) Antimicrobial11 PF08106.6 KUM64891.1 - 0.42 10.4 11.0 0.068 12.9 4.8 1.8 2 0 0 2 2 2 0 Formaecin family F-box-like PF12937.2 KUM64892.1 - 3.9e-05 23.2 0.1 0.00014 21.5 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KUM64892.1 - 0.00093 18.7 0.0 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain p450 PF00067.17 KUM64893.1 - 3.8e-44 150.9 0.0 6.8e-44 150.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 RTA1 PF04479.8 KUM64894.1 - 6.6e-20 71.5 5.6 7.6e-20 71.3 3.9 1.0 1 0 0 1 1 1 1 RTA1 like protein SHR3_chaperone PF08229.6 KUM64894.1 - 0.036 13.0 3.2 1.2 8.0 0.1 2.1 2 0 0 2 2 2 0 ER membrane protein SH3 YrhC PF14143.1 KUM64894.1 - 0.11 12.4 2.4 4.9 7.1 0.0 2.7 2 0 0 2 2 2 0 YrhC-like protein Ank_2 PF12796.2 KUM64895.1 - 0.00036 20.8 0.0 0.0094 16.2 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KUM64895.1 - 0.01 15.6 0.1 1.2 9.0 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeat Ank_3 PF13606.1 KUM64895.1 - 0.015 15.4 0.1 5.7 7.4 0.0 3.8 4 0 0 4 4 4 0 Ankyrin repeat F-box-like PF12937.2 KUM64895.1 - 0.018 14.7 0.6 0.12 12.1 0.0 2.3 2 0 0 2 2 2 0 F-box-like Nfu_N PF08712.6 KUM64897.1 - 6.3e-31 105.8 0.0 2.1e-29 100.9 0.0 2.3 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 KUM64897.1 - 6.2e-23 80.3 0.2 1.3e-22 79.2 0.1 1.6 1 0 0 1 1 1 1 NifU-like domain PSP1 PF04468.7 KUM64898.1 - 1.9e-30 104.6 1.3 3.1e-30 103.9 0.9 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region RasGEF PF00617.14 KUM64899.1 - 1.4e-44 152.0 0.9 2.4e-44 151.3 0.6 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KUM64899.1 - 1.3e-14 54.1 0.0 3.5e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 KUM64899.1 - 1.9e-07 31.5 0.0 4.6e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KUM64899.1 - 0.028 14.3 0.0 0.29 11.0 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase Trypan_PARP PF05887.6 KUM64900.1 - 0.74 9.6 8.5 1.4 8.7 5.9 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ATP_bind_3 PF01171.15 KUM64901.1 - 6e-20 71.5 0.0 9.3e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 PP-loop family RecR PF02132.10 KUM64901.1 - 0.0033 16.8 3.5 0.0033 16.8 2.4 2.4 3 0 0 3 3 3 1 RecR protein DUF2392 PF10288.4 KUM64901.1 - 0.0054 17.0 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 KUM64901.1 - 0.037 12.5 0.0 0.06 11.8 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase zf-UBR PF02207.15 KUM64901.1 - 0.93 9.2 10.8 0.99 9.1 0.6 2.6 3 0 0 3 3 3 0 Putative zinc finger in N-recognin (UBR box) Complex1_LYR_2 PF13233.1 KUM64902.1 - 4.2e-21 75.3 0.2 4.8e-21 75.1 0.2 1.0 1 0 0 1 1 1 1 Complex1_LYR-like TPR_6 PF13174.1 KUM64902.1 - 0.62 10.6 3.0 16 6.2 0.7 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat NAD_binding_4 PF07993.7 KUM64903.1 - 3.7e-27 94.8 0.0 5.5e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KUM64903.1 - 8.5e-09 35.1 0.0 8.1e-08 31.9 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KUM64903.1 - 1.2e-05 25.3 0.0 2.7e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM64903.1 - 0.00041 20.0 0.0 0.00081 19.0 0.0 1.4 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 KUM64903.1 - 0.00079 18.2 0.0 0.091 11.4 0.0 2.5 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KUM64903.1 - 0.0012 17.8 0.0 0.002 17.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 KUM64903.1 - 0.029 14.6 0.0 0.093 13.0 0.0 1.9 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ank_2 PF12796.2 KUM64904.1 - 6.1e-25 87.3 0.5 1.8e-12 47.4 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KUM64904.1 - 5.2e-24 82.8 1.4 5.9e-06 25.8 0.1 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 KUM64904.1 - 1e-18 65.5 0.1 0.0004 20.3 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 KUM64904.1 - 7.6e-18 64.5 1.2 1.1e-05 25.8 0.0 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM64904.1 - 4e-16 58.6 3.8 4.4e-07 29.9 0.3 4.4 2 1 3 5 5 5 4 Ankyrin repeats (many copies) ADH_N PF08240.7 KUM64905.1 - 1.9e-26 91.9 2.3 1.9e-26 91.9 1.6 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM64905.1 - 2e-13 50.0 0.0 4.2e-13 48.9 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase S1-like PF14444.1 KUM64905.1 - 0.0028 17.3 0.1 0.1 12.3 0.0 2.5 2 0 0 2 2 2 1 S1-like Glyco_hydro_31 PF01055.21 KUM64906.1 - 4.7e-164 546.4 0.0 3.6e-163 543.5 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KUM64906.1 - 3.1e-11 42.9 0.6 1.1e-10 41.2 0.4 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like tRNA-synt_2b PF00587.20 KUM64907.1 - 2.5e-46 157.4 0.0 4.4e-46 156.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KUM64907.1 - 1.1e-07 31.6 0.1 3.5e-07 30.0 0.1 1.8 1 1 0 1 1 1 1 Anticodon binding domain HMGL-like PF00682.14 KUM64908.1 - 8e-66 222.0 0.0 1.2e-65 221.5 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 KUM64908.1 - 2.8e-23 82.1 0.0 6.6e-23 80.9 0.0 1.7 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Glyco_hydro_16 PF00722.16 KUM64909.1 - 7e-43 146.0 3.0 7e-43 146.0 2.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 YjcZ PF13990.1 KUM64910.1 - 7.8e-05 21.9 0.0 0.00026 20.2 0.0 1.8 2 0 0 2 2 2 1 YjcZ-like protein Baculo_PEP_C PF04513.7 KUM64910.1 - 0.16 11.7 1.6 7.6 6.3 0.2 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ribosomal_S7 PF00177.16 KUM64911.1 - 2.3e-39 134.3 0.9 2.7e-39 134.0 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SDA1 PF05285.7 KUM64912.1 - 6.8e-94 314.7 33.8 6.8e-94 314.7 23.5 2.2 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 KUM64912.1 - 2.9e-21 75.5 0.3 7.5e-21 74.1 0.2 1.8 1 0 0 1 1 1 1 NUC130/3NT domain Sulfatase PF00884.18 KUM64913.1 - 4.5e-63 213.2 0.4 6.5e-63 212.7 0.3 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KUM64913.1 - 4.9e-07 29.4 0.3 1.1e-06 28.2 0.2 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase AMP-binding PF00501.23 KUM64914.1 - 6.2e-62 209.3 2.7 1.6e-24 86.0 0.6 4.7 3 1 0 3 3 3 3 AMP-binding enzyme DMAP_binding PF06464.6 KUM64914.1 - 1.1e-09 38.8 0.0 3.1e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.7 KUM64914.1 - 0.0031 17.2 0.2 0.0064 16.2 0.1 1.5 1 0 0 1 1 1 1 Gas vesicle protein G MFS_1 PF07690.11 KUM64915.1 - 3.7e-30 104.8 23.6 1.4e-29 102.9 16.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_31 PF01055.21 KUM64916.1 - 4.8e-85 286.0 0.2 7.8e-84 282.0 0.3 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KUM64916.1 - 3.7e-14 52.3 0.0 9.8e-14 50.9 0.0 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like Fungal_trans PF04082.13 KUM64918.1 - 1e-07 31.1 0.0 2e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KUM64920.1 - 1.1e-30 106.5 28.3 1.7e-30 105.9 19.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ADP_ribosyl_GH PF03747.9 KUM64920.1 - 1.4e-16 61.1 0.6 3.4e-14 53.3 0.1 2.3 1 1 1 2 2 2 2 ADP-ribosylglycohydrolase Sugar_tr PF00083.19 KUM64921.1 - 3.9e-105 352.0 29.5 4.7e-105 351.7 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM64921.1 - 7.5e-20 70.9 39.2 7.8e-15 54.4 10.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily V_ATPase_I PF01496.14 KUM64922.1 - 0.0027 15.6 2.0 0.0028 15.5 1.4 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CCDC155 PF14662.1 KUM64922.1 - 0.0051 16.4 4.6 0.0075 15.8 3.2 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 Fib_alpha PF08702.5 KUM64922.1 - 0.007 16.4 4.7 0.009 16.1 3.3 1.1 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Mnd1 PF03962.10 KUM64922.1 - 0.0098 15.5 5.9 0.011 15.3 4.1 1.1 1 0 0 1 1 1 1 Mnd1 family DUF4612 PF15389.1 KUM64922.1 - 0.025 15.1 6.1 0.038 14.6 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4612) OmpH PF03938.9 KUM64922.1 - 0.03 14.2 3.2 0.034 14.0 2.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) NYD-SP28 PF14772.1 KUM64922.1 - 0.041 13.9 10.4 0.06 13.4 7.2 1.3 1 0 0 1 1 1 0 Sperm tail IMD PF08397.6 KUM64922.1 - 0.081 12.2 5.9 0.088 12.1 4.1 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain His_Phos_2 PF00328.17 KUM64922.1 - 0.18 11.0 2.0 0.22 10.7 1.4 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) UPF0449 PF15136.1 KUM64922.1 - 0.31 11.2 3.0 0.7 10.1 2.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF718 PF05336.8 KUM64922.1 - 0.43 10.4 3.0 0.77 9.5 2.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF718) APG6 PF04111.7 KUM64922.1 - 0.51 9.3 9.2 0.63 9.0 6.4 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF904 PF06005.7 KUM64922.1 - 0.67 10.2 10.8 0.37 11.1 5.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) CENP-H PF05837.7 KUM64922.1 - 3.3 7.9 10.4 6.3 7.0 7.2 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) DivIC PF04977.10 KUM64922.1 - 4.5 6.8 7.8 0.62 9.5 2.5 1.8 2 0 0 2 2 2 0 Septum formation initiator PRP1_N PF06424.7 KUM64922.1 - 9.8 6.5 12.5 10 6.4 8.2 1.5 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal MFS_1 PF07690.11 KUM64924.1 - 8.3e-05 21.4 0.2 0.0001 21.1 0.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_S9 PF00326.16 KUM64925.1 - 1.1e-39 135.8 0.4 4.6e-38 130.5 0.3 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KUM64925.1 - 1.3e-13 51.3 1.3 3.1e-13 50.1 0.6 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM64925.1 - 4.9e-13 49.0 0.1 2.5e-11 43.5 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family PD40 PF07676.7 KUM64925.1 - 3e-08 33.1 0.1 0.11 12.1 0.0 3.7 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat Abhydrolase_2 PF02230.11 KUM64925.1 - 6.5e-08 32.2 0.0 0.0094 15.4 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DLH PF01738.13 KUM64925.1 - 1.9e-05 24.0 0.0 0.00097 18.4 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 KUM64925.1 - 4.6e-05 23.0 0.0 0.00011 21.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DPPIV_N PF00930.16 KUM64925.1 - 0.0012 17.4 0.0 0.47 8.9 0.0 2.6 2 1 1 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region LIP PF03583.9 KUM64925.1 - 0.0013 17.9 1.1 0.037 13.2 0.3 2.2 2 0 0 2 2 2 1 Secretory lipase FSH1 PF03959.8 KUM64925.1 - 0.0021 17.5 0.0 0.0065 15.9 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) eIF2A PF08662.6 KUM64925.1 - 0.057 13.1 0.0 0.34 10.6 0.0 2.1 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Abhydrolase_4 PF08386.5 KUM64925.1 - 0.087 12.7 0.2 0.46 10.4 0.0 2.1 2 0 0 2 2 2 0 TAP-like protein AXE1 PF05448.7 KUM64925.1 - 0.1 11.1 0.0 0.18 10.2 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Mtc PF03820.12 KUM64926.1 - 8.3e-102 339.9 0.3 3.9e-101 337.7 0.2 1.8 1 1 0 1 1 1 1 Tricarboxylate carrier Amidase PF01425.16 KUM64927.1 - 3.3e-85 286.5 0.3 4.4e-85 286.1 0.2 1.2 1 0 0 1 1 1 1 Amidase Pkinase PF00069.20 KUM64928.1 - 9.3e-55 185.5 0.0 1.5e-54 184.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM64928.1 - 2.5e-19 69.3 0.0 1.5e-18 66.8 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase TAF4 PF05236.9 KUM64929.1 - 5.2e-18 65.2 0.6 1.8e-11 43.7 0.2 3.1 2 1 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family Form-deh_trans PF09163.6 KUM64929.1 - 0.16 11.4 0.0 0.36 10.3 0.0 1.5 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane CPSF73-100_C PF11718.3 KUM64930.1 - 4.8e-75 251.6 0.0 8e-75 250.8 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 KUM64930.1 - 5.8e-31 107.0 0.0 1.4e-30 105.7 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 KUM64930.1 - 2.1e-15 56.8 0.4 4.2e-15 55.9 0.3 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KUM64930.1 - 5e-09 35.9 0.1 9.5e-09 35.0 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 KUM64930.1 - 5.6e-07 29.2 0.2 1.1e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 KUM64930.1 - 0.0055 16.4 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Aminotran_3 PF00202.16 KUM64931.1 - 1.3e-85 287.2 0.0 1.6e-85 286.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III TrkH PF02386.11 KUM64932.1 - 1.2e-11 43.7 14.2 1.6e-08 33.5 0.9 2.1 2 0 0 2 2 2 2 Cation transport protein DAO PF01266.19 KUM64933.1 - 3.1e-49 167.8 0.0 3.6e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KUM64933.1 - 3.3e-06 26.2 0.1 0.027 13.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain ThiF PF00899.16 KUM64933.1 - 2e-05 24.4 0.0 2e-05 24.4 0.0 2.1 3 0 0 3 3 2 1 ThiF family NAD_binding_8 PF13450.1 KUM64933.1 - 2.7e-05 24.1 0.0 8.3e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KUM64933.1 - 0.00041 20.3 0.0 0.0075 16.1 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KUM64933.1 - 0.0005 19.0 0.0 0.045 12.6 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 KUM64933.1 - 0.0072 16.7 0.0 0.034 14.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KUM64933.1 - 0.0088 16.1 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 KUM64933.1 - 0.022 13.8 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 KUM64933.1 - 0.028 14.1 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.1 KUM64933.1 - 0.032 14.4 0.0 0.065 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.1 KUM64933.1 - 0.04 13.9 0.0 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KUM64933.1 - 0.068 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 KUM64933.1 - 0.074 12.8 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Sterile PF03015.14 KUM64933.1 - 0.16 12.2 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein 3HCDH_N PF02737.13 KUM64933.1 - 0.19 11.3 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FrpC PF06901.7 KUM64933.1 - 0.19 11.2 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 RTX iron-regulated protein FrpC Noc2 PF03715.8 KUM64934.1 - 2.2e-121 404.3 0.0 2.2e-121 404.3 0.0 2.2 2 1 1 3 3 3 1 Noc2p family adh_short PF00106.20 KUM64934.1 - 0.047 13.6 0.0 0.16 11.8 0.0 2.0 1 0 0 1 1 1 0 short chain dehydrogenase TrkH PF02386.11 KUM64935.1 - 9.1e-64 215.2 0.0 1e-63 215.0 0.0 1.0 1 0 0 1 1 1 1 Cation transport protein Methyltransf_16 PF10294.4 KUM64936.1 - 3.4e-20 72.1 0.0 7.6e-20 71.0 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 KUM64936.1 - 0.0053 16.7 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM64936.1 - 0.0097 16.4 0.0 0.017 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM64936.1 - 0.025 14.1 0.0 0.095 12.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KUM64936.1 - 0.061 12.7 0.0 0.12 11.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain VPS28 PF03997.7 KUM64937.1 - 4.6e-60 202.4 0.0 6.6e-60 201.9 0.0 1.2 1 0 0 1 1 1 1 VPS28 protein Dak2 PF02734.12 KUM64937.1 - 0.029 14.0 0.1 0.054 13.1 0.1 1.4 1 0 0 1 1 1 0 DAK2 domain GvpG PF05120.7 KUM64937.1 - 7.5 6.4 6.4 1.2 9.0 0.2 2.4 3 0 0 3 3 3 0 Gas vesicle protein G DEAD PF00270.24 KUM64938.1 - 9.7e-28 96.7 0.0 1.3e-26 93.1 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM64938.1 - 3.7e-23 81.1 0.1 4.5e-22 77.7 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KUM64938.1 - 0.00012 21.9 0.8 0.00035 20.4 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KUM64938.1 - 0.049 13.3 0.1 0.19 11.5 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain LEA_4 PF02987.11 KUM64940.1 - 0.041 13.7 0.2 0.061 13.2 0.1 1.3 1 0 0 1 1 1 0 Late embryogenesis abundant protein CtnDOT_TraJ PF07863.6 KUM64940.1 - 2.9 8.4 4.8 4.2 7.9 3.3 1.3 1 0 0 1 1 1 0 Homologues of TraJ from Bacteroides conjugative transposon Herpes_capsid PF06112.6 KUM64940.1 - 5.2 7.0 8.7 5.9 6.9 6.1 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein ATP-synt_G PF04718.10 KUM64941.1 - 5.7e-22 78.3 0.0 6.3e-22 78.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit Zn_clus PF00172.13 KUM64942.1 - 3.3e-11 42.9 10.0 4.9e-11 42.3 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AKNA PF12443.3 KUM64942.1 - 0.0091 15.9 1.0 0.019 14.9 0.7 1.5 1 0 0 1 1 1 1 AT-hook-containing transcription factor IncA PF04156.9 KUM64942.1 - 0.046 13.3 1.0 0.057 13.0 0.7 1.3 1 0 0 1 1 1 0 IncA protein DUF4206 PF13901.1 KUM64942.1 - 0.12 11.8 0.1 0.12 11.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4206) DUF2802 PF10975.3 KUM64942.1 - 0.86 9.4 2.9 0.97 9.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) EMP24_GP25L PF01105.19 KUM64942.1 - 1.3 8.7 4.0 2.8 7.6 1.4 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Fungal_trans PF04082.13 KUM64943.1 - 0.0015 17.4 0.1 0.002 17.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Caps_synth PF05704.7 KUM64943.1 - 0.15 11.2 0.2 0.19 10.8 0.2 1.0 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein GST_N PF02798.15 KUM64946.1 - 1.8e-13 50.4 0.0 4.3e-13 49.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KUM64946.1 - 7.8e-13 48.2 0.0 1.3e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KUM64946.1 - 1.1e-12 47.8 0.1 2.8e-12 46.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KUM64946.1 - 1.3e-12 47.7 0.0 2.3e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KUM64946.1 - 2e-06 28.1 0.0 3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KUM64946.1 - 1.1e-05 25.2 0.0 2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 KUM64946.1 - 0.039 14.3 0.0 0.065 13.6 0.0 1.3 1 0 0 1 1 1 0 MetRS-N binding domain DUF3791 PF12668.2 KUM64946.1 - 0.073 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) RNR_inhib PF08591.5 KUM64947.1 - 3.6e-16 59.8 0.2 7.1e-16 58.9 0.1 1.5 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor DUF2293 PF10056.4 KUM64949.1 - 5.3e-30 103.2 0.7 1.4e-29 101.9 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) RE_BstXI PF09552.5 KUM64949.1 - 0.00016 20.8 0.0 0.0057 15.7 0.0 2.1 2 0 0 2 2 2 2 BstXI restriction endonuclease Gly_transf_sug PF04488.10 KUM64951.1 - 1.6e-11 44.4 0.7 1.2e-10 41.6 0.5 2.2 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KUM64951.1 - 1.6e-05 23.6 0.1 0.0082 14.6 0.0 2.1 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain Pyr_redox_3 PF13738.1 KUM64953.1 - 4e-24 85.7 0.0 5.1e-22 78.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KUM64953.1 - 1.5e-10 40.5 0.0 3.2e-08 32.8 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KUM64953.1 - 2.4e-05 24.1 0.2 0.32 10.7 0.0 3.4 3 0 0 3 3 3 2 FAD-NAD(P)-binding FMO-like PF00743.14 KUM64953.1 - 3.4e-05 22.2 0.0 0.00018 19.8 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Shikimate_DH PF01488.15 KUM64953.1 - 8.5e-05 22.6 0.1 0.00085 19.4 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 KUM64953.1 - 0.00034 20.5 0.9 4.1 7.2 0.6 3.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KUM64953.1 - 0.0014 18.8 0.0 0.031 14.5 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 KUM64953.1 - 0.0044 17.0 0.0 0.013 15.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 KUM64953.1 - 0.1 11.7 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CPSase_L_chain PF00289.17 KUM64953.1 - 0.14 12.2 0.1 0.52 10.4 0.0 1.9 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain DUF498 PF04430.9 KUM64953.1 - 0.14 11.7 0.0 13 5.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF498/DUF598) Hexokinase_1 PF00349.16 KUM64955.1 - 0.034 13.4 0.0 0.049 12.9 0.0 1.1 1 0 0 1 1 1 0 Hexokinase DnaJ PF00226.26 KUM64956.1 - 4.9e-19 67.8 0.6 4.9e-19 67.8 0.4 2.0 2 0 0 2 2 2 1 DnaJ domain MBOAT PF03062.14 KUM64957.1 - 2.8e-36 125.2 19.6 5.9e-36 124.2 13.6 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Ribosomal_L13 PF00572.13 KUM64958.1 - 1.3e-27 96.4 0.0 2.7e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L13 DSBA PF01323.15 KUM64958.1 - 0.024 14.1 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Metallophos_2 PF12850.2 KUM64959.1 - 1.5e-07 31.3 0.1 3.6e-07 30.1 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KUM64959.1 - 3.8e-07 29.6 2.3 1e-06 28.2 1.6 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase AMP-binding PF00501.23 KUM64960.1 - 1.8e-48 164.9 0.2 2.2e-48 164.6 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KUM64960.1 - 6.8e-16 58.9 0.0 1.3e-15 58.0 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 KUM64961.1 - 6.5e-09 34.6 0.0 7.7e-09 34.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Peptidase_M28 PF04389.12 KUM64962.1 - 1.8e-30 105.9 0.1 2.9e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KUM64962.1 - 0.0011 18.4 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 F-box-like PF12937.2 KUM64963.1 - 4.2e-12 45.6 0.0 1.4e-11 43.8 0.0 2.0 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KUM64963.1 - 1.8e-11 43.6 14.2 0.0042 16.7 0.3 6.6 3 1 5 8 8 8 6 Leucine rich repeat LRR_4 PF12799.2 KUM64963.1 - 3.6e-09 36.0 10.4 0.34 10.6 0.0 7.5 5 2 5 10 10 10 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KUM64963.1 - 3e-08 32.8 14.3 4.7 7.5 0.0 10.9 13 0 0 13 13 13 1 Leucine Rich repeat F-box PF00646.28 KUM64963.1 - 6.9e-05 22.3 0.0 0.00033 20.2 0.0 2.3 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.28 KUM64963.1 - 0.0014 18.3 20.1 72 4.0 0.0 10.2 8 3 0 8 8 8 0 Leucine Rich Repeat DUF1699 PF08004.6 KUM64963.1 - 0.017 14.6 1.6 0.15 11.5 0.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1699) Recep_L_domain PF01030.19 KUM64963.1 - 0.046 13.7 0.4 57 3.7 0.0 4.1 1 1 3 5 5 5 0 Receptor L domain Epimerase PF01370.16 KUM64964.1 - 3.6e-26 92.0 0.0 6.7e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KUM64964.1 - 1e-11 45.1 0.0 9.2e-11 42.0 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KUM64964.1 - 4.9e-11 42.0 0.0 2.4e-09 36.5 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KUM64964.1 - 3.9e-09 35.6 0.0 1.5e-08 33.6 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KUM64964.1 - 5.4e-08 32.0 0.0 8.8e-08 31.3 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 KUM64964.1 - 0.0039 17.1 0.1 0.014 15.2 0.0 2.1 2 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KUM64964.1 - 0.0053 15.6 0.0 0.025 13.4 0.0 2.0 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.8 KUM64964.1 - 0.026 13.7 0.1 0.078 12.2 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family KR PF08659.5 KUM64964.1 - 0.03 13.9 0.2 0.12 11.9 0.1 2.0 1 1 0 1 1 1 0 KR domain Pkinase PF00069.20 KUM64967.1 - 3.8e-61 206.5 0.0 4.6e-61 206.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM64967.1 - 2.8e-36 124.9 0.0 3.8e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM64967.1 - 1.5e-09 37.2 0.0 2.2e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KUM64967.1 - 0.14 11.2 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sec39 PF08314.6 KUM64968.1 - 1.7e-248 826.2 5.0 1.9e-248 826.0 3.5 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 F-box-like PF12937.2 KUM64970.1 - 2.2e-05 24.0 0.0 6.2e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 KUM64970.1 - 0.0033 17.3 0.1 50 4.4 0.0 4.6 4 0 0 4 4 4 0 Leucine Rich repeat F-box PF00646.28 KUM64970.1 - 0.0062 16.1 0.6 0.048 13.3 0.0 2.5 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.28 KUM64970.1 - 0.018 14.9 0.6 32 5.0 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat Ribosomal_S26e PF01283.14 KUM64971.1 - 1.6e-51 173.3 6.6 2.3e-51 172.8 4.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.2 KUM64971.1 - 0.033 14.5 2.5 0.38 11.1 1.1 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain CBS PF00571.23 KUM64972.1 - 1.1e-41 140.3 7.5 1.7e-09 37.3 0.0 5.2 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 KUM64972.1 - 6e-10 38.6 0.0 1.6e-09 37.2 0.0 1.8 1 1 0 1 1 1 1 PB1 domain HEAT_2 PF13646.1 KUM64973.1 - 3e-19 69.1 12.2 7.7e-07 29.3 0.2 8.7 5 2 4 10 10 10 5 HEAT repeats HEAT_EZ PF13513.1 KUM64973.1 - 3e-19 68.9 19.8 6.8e-08 32.7 0.3 10.5 9 2 2 11 11 11 4 HEAT-like repeat HEAT PF02985.17 KUM64973.1 - 7.2e-18 63.0 12.5 0.0045 16.9 0.0 11.7 13 0 0 13 13 12 3 HEAT repeat Vac14_Fab1_bd PF12755.2 KUM64973.1 - 1.4e-09 38.2 0.6 0.0057 17.0 0.0 5.9 2 2 3 5 5 5 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 KUM64973.1 - 2e-08 33.8 0.7 0.13 11.5 0.0 6.2 4 4 2 6 6 6 3 CLASP N terminal RIX1 PF08167.7 KUM64973.1 - 7.1e-08 32.3 0.0 0.07 12.7 0.0 5.3 4 1 2 6 6 6 2 rRNA processing/ribosome biogenesis Adaptin_N PF01602.15 KUM64973.1 - 1.9e-06 26.5 0.1 0.0035 15.7 0.1 3.2 1 1 0 2 2 2 2 Adaptin N terminal region Proteasom_PSMB PF10508.4 KUM64973.1 - 5.9e-05 21.5 0.4 0.005 15.1 0.0 2.7 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit MMS19_C PF12460.3 KUM64973.1 - 0.00058 18.7 0.8 0.00058 18.7 0.6 4.3 4 2 2 6 6 6 1 RNAPII transcription regulator C-terminal Cnd1 PF12717.2 KUM64973.1 - 0.001 18.9 0.6 5.8 6.7 0.0 4.8 3 1 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.3 KUM64973.1 - 0.0013 18.7 0.1 13 5.7 0.0 4.8 4 1 0 5 5 5 0 Domain of unknown function (DUF3385) Arm PF00514.18 KUM64973.1 - 0.0052 16.5 8.0 0.89 9.4 0.1 4.9 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat DUF4042 PF13251.1 KUM64973.1 - 0.0064 15.9 0.7 22 4.4 0.0 4.8 5 1 0 5 5 5 0 Domain of unknown function (DUF4042) IBN_N PF03810.14 KUM64973.1 - 0.017 14.9 0.1 0.15 11.9 0.0 2.8 2 0 0 2 2 2 0 Importin-beta N-terminal domain SEN1_N PF12726.2 KUM64973.1 - 0.075 11.0 3.1 0.074 11.0 0.1 2.4 3 0 0 3 3 3 0 SEN1 N terminal Fe-ADH PF00465.14 KUM64975.1 - 1.1e-69 234.8 0.0 1.3e-69 234.6 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KUM64975.1 - 3.4e-11 42.9 0.0 2.6e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Glyco_hydro_28 PF00295.12 KUM64976.1 - 1.2e-41 142.7 6.1 1.2e-40 139.5 4.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Bac_rhamnosid PF05592.6 KUM64977.1 - 7.6e-32 110.1 3.3 7e-24 83.9 2.3 2.4 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase Trehalase PF01204.13 KUM64977.1 - 0.0018 17.0 0.1 0.0027 16.4 0.1 1.1 1 0 0 1 1 1 1 Trehalase DUF608 PF04685.8 KUM64977.1 - 0.0026 16.5 9.0 0.0069 15.1 6.2 1.6 1 1 1 2 2 2 2 Protein of unknown function, DUF608 Chalcone PF02431.10 KUM64978.1 - 2.9e-65 219.4 0.0 3.7e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Pro_racemase PF05544.6 KUM64979.1 - 3.4e-128 427.0 0.1 3.8e-128 426.8 0.0 1.0 1 0 0 1 1 1 1 Proline racemase CorA PF01544.13 KUM64980.1 - 0.00013 21.1 4.8 0.00026 20.1 3.4 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Lipase_GDSL_2 PF13472.1 KUM64981.1 - 5.5e-20 72.2 0.1 6.9e-20 71.9 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KUM64981.1 - 6.6e-08 32.6 0.0 8e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 KUM64981.1 - 1.2e-05 25.1 0.0 0.025 14.3 0.0 2.5 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family AA_permease_2 PF13520.1 KUM64984.1 - 4.8e-48 163.7 51.4 6.1e-48 163.4 35.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM64984.1 - 3.9e-30 104.6 48.0 4.9e-30 104.2 33.3 1.0 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.3 KUM64985.1 - 5.4e-24 84.5 3.8 7.9e-24 83.9 2.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM64985.1 - 0.013 15.4 6.4 0.013 15.4 4.5 1.7 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3535 PF12054.3 KUM64986.1 - 5.8e-151 503.0 0.0 1.7e-150 501.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 KUM64986.1 - 4.3e-70 235.8 0.0 7.5e-70 235.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 KUM64986.1 - 1.1e-16 59.3 10.0 0.2 11.8 0.0 9.8 10 0 0 10 10 10 6 HEAT repeat Helicase_C PF00271.26 KUM64986.1 - 2.3e-14 52.9 0.0 6.8e-14 51.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vac14_Fab1_bd PF12755.2 KUM64986.1 - 4.8e-07 30.0 0.0 0.11 12.9 0.0 4.0 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 KUM64986.1 - 3e-05 24.2 13.6 0.055 13.7 0.1 7.2 7 1 2 9 9 9 2 HEAT repeats HEAT_EZ PF13513.1 KUM64986.1 - 0.0014 19.0 16.7 3.8 8.1 0.0 8.6 9 0 0 9 9 9 1 HEAT-like repeat CLASP_N PF12348.3 KUM64986.1 - 0.0061 15.9 0.1 2.9 7.2 0.0 3.9 3 1 2 5 5 5 1 CLASP N terminal Cnd1 PF12717.2 KUM64986.1 - 0.026 14.3 0.3 2.5 7.9 0.0 4.0 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Ndufs5 PF10200.4 KUM64987.1 - 0.0005 19.9 0.0 0.0007 19.5 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.3 KUM64987.1 - 0.0095 16.0 0.1 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) COX6B PF02297.12 KUM64987.1 - 0.01 15.8 0.1 0.016 15.1 0.1 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 KUM64987.1 - 0.014 15.3 0.1 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 CHCH domain LysM PF01476.15 KUM64988.1 - 0.00027 20.7 0.0 0.0005 19.9 0.0 1.5 1 0 0 1 1 1 1 LysM domain adh_short PF00106.20 KUM64989.1 - 2.3e-14 53.6 0.0 3.3e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM64989.1 - 2.3e-08 33.9 0.0 3.2e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KUM64989.1 - 4.7e-05 23.2 0.0 7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KUM64989.1 - 0.13 12.2 0.0 0.65 9.9 0.0 2.0 1 1 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 KUM64989.1 - 0.14 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans_2 PF11951.3 KUM64990.1 - 0.19 10.2 7.4 0.025 13.1 2.1 1.6 2 0 0 2 2 2 0 Fungal specific transcription factor domain Med15_fungi PF05397.7 KUM64991.1 - 1.1e-29 102.7 0.3 1.1e-29 102.7 0.2 5.2 6 0 0 6 6 6 1 Mediator complex subunit 15 LMBR1 PF04791.11 KUM64992.1 - 4.8e-29 101.2 0.7 6.8e-29 100.7 0.5 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein Syntaxin_2 PF14523.1 KUM64992.1 - 0.24 11.4 0.0 0.5 10.4 0.0 1.4 1 0 0 1 1 1 0 Syntaxin-like protein IncA PF04156.9 KUM64992.1 - 0.25 10.9 0.0 0.25 10.9 0.0 2.4 2 1 0 2 2 2 0 IncA protein BAG PF02179.11 KUM64993.1 - 8.4e-15 54.6 0.0 1.6e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 KUM64993.1 - 0.0021 17.4 0.0 0.0037 16.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family YopE_N PF09020.5 KUM64993.1 - 3.6 7.6 8.2 12 5.9 0.6 2.3 2 0 0 2 2 2 0 YopE, N terminal DUF605 PF04652.11 KUM64993.1 - 4.5 6.5 12.1 6.6 6.0 8.4 1.2 1 0 0 1 1 1 0 Vta1 like Glutaredoxin PF00462.19 KUM64995.1 - 1.3e-21 76.2 0.1 2.3e-21 75.5 0.0 1.4 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_2 PF13098.1 KUM64995.1 - 0.0025 18.0 0.2 0.017 15.3 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.9 KUM64995.1 - 0.0051 17.0 0.1 0.0066 16.6 0.0 1.4 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.1 KUM64995.1 - 0.015 15.2 0.4 4 7.4 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin DSBA PF01323.15 KUM64995.1 - 0.057 12.9 0.1 0.88 9.1 0.1 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain TraF PF13728.1 KUM64995.1 - 0.067 12.6 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin PF00085.15 KUM64995.1 - 0.067 12.8 0.0 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.1 KUM64995.1 - 0.072 13.1 0.0 0.16 11.9 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like DUF244 PF03112.9 KUM64995.1 - 0.14 11.6 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF Toprim PF01751.17 KUM64995.1 - 0.15 12.0 0.2 0.27 11.2 0.1 1.7 1 1 0 1 1 1 0 Toprim domain Adaptin_N PF01602.15 KUM64996.1 - 1e-139 466.2 0.9 1.2e-139 466.0 0.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 KUM64996.1 - 1e-15 58.0 0.0 1.8e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 KUM64996.1 - 1.9e-07 31.2 1.6 0.014 15.6 0.0 4.0 3 1 0 3 3 3 2 HEAT repeats Cnd1 PF12717.2 KUM64996.1 - 0.0028 17.5 5.3 0.014 15.2 0.6 3.3 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KUM64996.1 - 0.0052 16.7 1.8 13 6.1 0.0 4.8 5 1 0 5 5 5 1 HEAT repeat TIP120 PF08623.5 KUM64996.1 - 0.0087 15.6 0.3 0.042 13.4 0.0 2.1 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) HEAT_EZ PF13513.1 KUM64996.1 - 0.014 15.8 0.2 6.4 7.3 0.0 4.6 3 1 2 5 5 5 0 HEAT-like repeat Arm PF00514.18 KUM64996.1 - 0.023 14.5 0.4 72 3.4 0.1 5.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Nuc_sug_transp PF04142.10 KUM64997.1 - 1.2e-09 37.5 0.6 2e-09 36.9 0.4 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 KUM64997.1 - 8.8e-09 35.4 20.9 8.7e-06 25.7 1.3 3.1 2 1 1 3 3 3 3 EamA-like transporter family UAA PF08449.6 KUM64997.1 - 2.2e-08 33.3 6.5 3.6e-08 32.6 4.5 1.2 1 0 0 1 1 1 1 UAA transporter family O-antigen_lig PF13425.1 KUM64997.1 - 0.00073 19.5 1.8 0.00073 19.5 1.3 3.0 4 1 0 4 4 4 1 O-antigen ligase like membrane protein TPT PF03151.11 KUM64997.1 - 0.00092 18.8 18.4 0.037 13.6 5.8 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 KUM64997.1 - 0.0022 18.1 6.1 0.0022 18.1 4.2 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter DUF3353 PF11833.3 KUM64997.1 - 0.68 9.3 4.8 2.7 7.4 3.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3353) Ribonuc_L-PSP PF01042.16 KUM64998.1 - 1.9e-30 105.1 0.0 7.6e-22 77.3 0.0 2.0 1 1 1 2 2 2 2 Endoribonuclease L-PSP PALP PF00291.20 KUM64999.1 - 6.6e-42 143.8 0.0 7.5e-42 143.6 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme 60KD_IMP PF02096.15 KUM65000.1 - 9.5e-15 54.7 0.2 1.2e-14 54.4 0.2 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein PP2C PF00481.16 KUM65001.1 - 2e-42 145.3 0.0 3.8e-42 144.4 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KUM65001.1 - 0.00032 20.1 0.0 0.00071 19.0 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KUM65001.1 - 0.0009 18.9 0.0 1.6 8.4 0.0 3.2 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) Ank_2 PF12796.2 KUM65002.1 - 9.8e-14 51.4 0.2 2.9e-09 37.1 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KUM65002.1 - 4.5e-09 35.6 0.0 0.0037 17.3 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 KUM65002.1 - 5.3e-09 35.4 0.0 0.00017 21.2 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KUM65002.1 - 9.2e-08 32.0 0.1 0.0044 17.2 0.0 3.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KUM65002.1 - 2.2e-05 24.8 0.7 0.0055 17.2 0.1 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) PPR_3 PF13812.1 KUM65002.1 - 0.032 14.5 0.1 7 7.2 0.0 3.1 3 0 0 3 3 3 0 Pentatricopeptide repeat domain Glycos_transf_1 PF00534.15 KUM65003.1 - 2.4e-19 69.3 0.0 3.7e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KUM65003.1 - 3.3e-09 36.9 0.0 1.9e-08 34.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KUM65003.1 - 0.00016 21.4 0.1 0.00078 19.2 0.0 2.2 3 0 0 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 KUM65003.1 - 0.0044 17.2 0.1 0.0087 16.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 AAA_5 PF07728.9 KUM65003.1 - 0.018 14.7 0.0 0.041 13.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TFIIS_C PF01096.13 KUM65004.1 - 3.3e-20 71.4 2.3 3.3e-20 71.4 1.6 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KUM65004.1 - 6.4e-08 32.1 3.4 2.6e-07 30.2 0.5 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_ribbon_recom PF13408.1 KUM65004.1 - 0.007 16.5 0.3 0.59 10.4 0.0 2.4 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain Elf1 PF05129.8 KUM65004.1 - 0.011 15.4 2.6 0.86 9.3 0.2 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-ribbon_3 PF13248.1 KUM65004.1 - 0.021 14.0 10.9 0.17 11.1 2.3 3.3 3 1 0 3 3 3 0 zinc-ribbon domain IBR PF01485.16 KUM65004.1 - 0.029 14.2 6.6 0.76 9.6 0.2 2.9 2 1 0 2 2 2 0 IBR domain Zn_Tnp_IS1595 PF12760.2 KUM65004.1 - 0.042 13.6 7.0 1.2 9.0 0.7 2.6 2 2 0 2 2 2 0 Transposase zinc-ribbon domain NOB1_Zn_bind PF08772.6 KUM65004.1 - 0.073 12.9 1.2 0.27 11.1 0.1 2.1 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_4 PF13717.1 KUM65004.1 - 0.2 11.3 8.6 1.9 8.2 0.1 3.0 3 1 0 3 3 2 0 zinc-ribbon domain DZR PF12773.2 KUM65004.1 - 0.23 11.3 6.7 0.27 11.0 0.2 2.5 2 1 0 2 2 2 0 Double zinc ribbon zinc_ribbon_5 PF13719.1 KUM65004.1 - 0.24 11.0 8.0 1.7 8.2 0.1 3.0 3 1 0 3 3 3 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 KUM65004.1 - 0.79 9.0 5.9 2.9 7.3 0.0 2.8 3 0 0 3 3 3 0 TFIIB zinc-binding zf-H2C2_2 PF13465.1 KUM65004.1 - 0.92 9.9 6.5 8.5 6.8 0.1 3.6 4 0 0 4 4 4 0 Zinc-finger double domain Zn_Tnp_IS1 PF03811.8 KUM65004.1 - 1.4 8.4 8.4 0.14 11.6 0.9 2.8 3 1 0 3 3 3 0 InsA N-terminal domain zf-TFIIB PF13453.1 KUM65004.1 - 1.8 7.8 8.2 0.24 10.6 0.4 2.8 3 0 0 3 3 3 0 Transcription factor zinc-finger Rubredoxin PF00301.15 KUM65004.1 - 4.9 7.1 6.6 16 5.4 0.1 3.5 4 0 0 4 4 4 0 Rubredoxin Nudix_N_2 PF14803.1 KUM65004.1 - 6.3 6.5 7.0 21 4.8 1.7 3.0 2 1 0 2 2 2 0 Nudix N-terminal MAGE PF01454.14 KUM65006.1 - 1e-41 142.4 0.0 1.3e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 MAGE family GTP_EFTU PF00009.22 KUM65007.1 - 2.9e-57 193.1 0.0 4.2e-57 192.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KUM65007.1 - 9.7e-37 125.1 0.1 3.6e-36 123.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KUM65007.1 - 1.3e-14 54.0 0.8 3.9e-14 52.5 0.6 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KUM65007.1 - 0.00014 21.4 0.2 0.00035 20.1 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 KUM65007.1 - 0.0017 18.2 0.3 0.0067 16.3 0.2 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Semialdhyde_dhC PF02774.13 KUM65007.1 - 0.015 15.1 0.1 0.22 11.3 0.0 2.2 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain MFS_1 PF07690.11 KUM65010.1 - 2.1e-24 85.9 13.7 2.5e-24 85.6 9.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM65010.1 - 8.8e-06 24.5 7.5 9.9e-06 24.3 5.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1616 PF07760.6 KUM65010.1 - 0.013 14.7 2.2 0.027 13.6 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) adh_short_C2 PF13561.1 KUM65011.1 - 1.5e-24 87.0 0.0 2e-24 86.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KUM65011.1 - 5.5e-24 84.9 0.4 6.8e-24 84.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM65011.1 - 5.3e-09 36.0 0.0 8.2e-09 35.3 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KUM65011.1 - 0.014 15.3 0.4 0.029 14.4 0.3 1.7 1 1 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 KUM65011.1 - 0.13 10.9 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Fungal_trans_2 PF11951.3 KUM65012.1 - 5.8e-14 51.4 0.0 2.3e-13 49.5 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM65012.1 - 1.1e-07 31.6 10.6 2e-07 30.7 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transketolase_N PF00456.16 KUM65013.1 - 3.5e-119 397.5 0.1 1.8e-118 395.2 0.0 1.9 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KUM65013.1 - 2.1e-38 131.6 0.2 5.6e-38 130.1 0.1 1.8 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KUM65013.1 - 1.3e-06 27.3 0.2 2.8e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KUM65013.1 - 1.6e-06 27.2 0.0 3.4e-05 22.9 0.0 2.5 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.15 KUM65013.1 - 2.4e-05 24.2 0.0 6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.16 KUM65013.1 - 8.7e-05 22.1 2.8 0.003 17.1 0.9 3.1 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain GSHPx PF00255.14 KUM65013.1 - 0.023 14.0 0.0 4 6.8 0.0 2.4 2 0 0 2 2 2 0 Glutathione peroxidase DEAD PF00270.24 KUM65014.1 - 7e-45 152.5 0.0 1e-44 152.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM65014.1 - 3.9e-25 87.5 0.0 8.8e-25 86.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Brix PF04427.13 KUM65015.1 - 2.2e-57 193.8 0.4 3e-57 193.3 0.3 1.2 1 0 0 1 1 1 1 Brix domain MoCF_biosynth PF00994.19 KUM65016.1 - 2.9e-29 101.3 0.0 7.4e-15 54.6 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 KUM65016.1 - 1.2e-27 96.2 0.5 1.7e-27 95.7 0.4 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 KUM65016.1 - 1.2e-10 41.1 0.1 7.4e-10 38.6 0.0 2.3 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) Acetyltransf_10 PF13673.1 KUM65019.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 KUM65020.1 - 1.6e-39 135.6 31.1 1.6e-39 135.6 21.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM65020.1 - 9.6e-14 50.7 18.3 2.6e-13 49.3 12.7 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KUM65020.1 - 1.9e-08 33.0 5.7 3.2e-08 32.2 3.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 KUM65020.1 - 0.0062 14.7 6.9 0.015 13.4 3.5 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector Corona_S2 PF01601.11 KUM65020.1 - 0.35 8.9 1.0 0.56 8.2 0.7 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Snf7 PF03357.16 KUM65021.1 - 1.8e-33 115.3 19.3 1.8e-33 115.3 13.4 2.0 1 1 1 2 2 2 1 Snf7 Fmp27_WPPW PF10359.4 KUM65021.1 - 0.15 10.4 8.8 0.19 10.0 6.1 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain IFT57 PF10498.4 KUM65021.1 - 0.68 8.6 13.5 0.83 8.3 8.9 1.5 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 NuA4 PF09340.5 KUM65021.1 - 1 9.0 4.7 0.45 10.1 0.3 2.5 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 TMCO5 PF14992.1 KUM65021.1 - 2 7.4 17.3 1.4 8.0 10.9 1.5 1 1 1 2 2 2 0 TMCO5 family DUF3573 PF12097.3 KUM65021.1 - 2.2 6.8 7.8 3.7 6.0 5.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) Atg14 PF10186.4 KUM65021.1 - 3.1 6.6 14.0 5.1 5.9 9.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Aconitase PF00330.15 KUM65022.1 - 5.8e-156 519.6 0.0 2.6e-155 517.4 0.0 1.8 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KUM65022.1 - 1.1e-38 132.2 0.0 1.8e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF2370 PF10176.4 KUM65023.1 - 0.0054 16.1 0.7 0.0054 16.1 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) TMEM52 PF14979.1 KUM65023.1 - 0.093 12.6 0.4 0.1 12.4 0.3 1.1 1 0 0 1 1 1 0 Transmembrane 52 zf-H2C2_2 PF13465.1 KUM65024.1 - 1.4e-13 50.3 8.3 5.8e-08 32.6 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KUM65024.1 - 9.4e-12 44.5 12.3 9e-06 25.7 1.6 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KUM65024.1 - 1.4e-10 40.7 12.8 4.3e-05 23.5 1.8 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KUM65024.1 - 3.2e-07 30.2 1.8 0.033 14.3 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KUM65024.1 - 4.5e-05 23.4 1.2 0.015 15.4 0.2 3.0 3 0 0 3 3 3 1 Zinc-finger of C2H2 type DUF4415 PF14384.1 KUM65024.1 - 0.039 14.1 0.0 0.09 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4415) zf-Di19 PF05605.7 KUM65024.1 - 0.12 12.5 1.7 0.23 11.5 1.2 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 KUM65024.1 - 0.82 9.6 7.9 12 5.9 0.4 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger LIM PF00412.17 KUM65024.1 - 1.1 9.3 2.8 8.9 6.4 2.0 2.2 1 1 1 2 2 2 0 LIM domain PQ-loop PF04193.9 KUM65025.1 - 1.1e-38 130.5 7.6 2.7e-20 71.6 0.3 2.6 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 KUM65025.1 - 0.03 14.1 3.3 0.18 11.7 0.0 2.4 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Tcf25 PF04910.9 KUM65026.1 - 2.4e-89 299.8 0.1 3.9e-89 299.0 0.0 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 DUF3773 PF12608.3 KUM65026.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3773) Nop14 PF04147.7 KUM65026.1 - 5.6 4.7 16.0 7.8 4.2 11.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2408 PF10303.4 KUM65027.1 - 1.9e-54 183.4 6.0 1.7e-34 118.7 0.7 5.1 2 2 3 5 5 5 4 Protein of unknown function (DUF2408) Spc7 PF08317.6 KUM65027.1 - 0.0064 15.1 0.7 0.0064 15.1 0.5 1.8 2 0 0 2 2 2 1 Spc7 kinetochore protein EzrA PF06160.7 KUM65027.1 - 0.0067 14.6 2.3 0.06 11.5 0.1 2.3 2 1 0 2 2 2 1 Septation ring formation regulator, EzrA DUF2383 PF09537.5 KUM65027.1 - 0.031 14.5 0.3 0.099 12.8 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) PTRF_SDPR PF15237.1 KUM65027.1 - 0.035 13.4 0.3 0.091 12.1 0.2 1.6 1 0 0 1 1 1 0 PTRF/SDPR family Snapin_Pallidin PF14712.1 KUM65027.1 - 0.097 12.9 5.7 0.16 12.2 0.3 3.7 4 0 0 4 4 4 0 Snapin/Pallidin DUF1664 PF07889.7 KUM65027.1 - 0.1 12.3 0.2 3.4 7.4 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 KUM65027.1 - 0.27 11.0 1.9 0.53 10.0 0.7 2.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HR1 PF02185.11 KUM65027.1 - 0.65 9.7 6.5 1.3 8.8 0.1 3.6 3 1 1 4 4 4 0 Hr1 repeat Prefoldin_2 PF01920.15 KUM65027.1 - 1.7 8.4 7.8 15 5.4 0.1 3.7 2 1 1 4 4 4 0 Prefoldin subunit Ribosomal_60s PF00428.14 KUM65028.1 - 8.6e-25 86.9 9.0 1.2e-24 86.5 6.2 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_L27e PF01777.13 KUM65029.1 - 1.4e-36 124.4 1.1 1.8e-36 124.1 0.8 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 KUM65029.1 - 0.0043 16.7 1.8 0.0043 16.7 1.2 1.9 2 0 0 2 2 2 1 KOW motif SAP30_Sin3_bdg PF13867.1 KUM65030.1 - 0.00021 21.0 5.2 1.7 8.6 0.0 7.1 8 1 1 9 9 9 2 Sin3 binding region of histone deacetylase complex subunit SAP30 Proteasome PF00227.21 KUM65030.1 - 0.037 13.2 2.4 3.4 6.9 0.1 4.3 3 1 0 3 3 3 0 Proteasome subunit Sec34 PF04136.10 KUM65030.1 - 1.1 8.9 16.2 0.39 10.4 2.0 5.8 4 0 0 4 4 4 0 Sec34-like family adh_short PF00106.20 KUM65031.1 - 4.6e-28 98.2 1.3 6.8e-28 97.6 0.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM65031.1 - 3.7e-12 46.2 0.3 6.5e-12 45.4 0.2 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KUM65031.1 - 4.2e-10 39.7 0.0 6.3e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KUM65031.1 - 0.041 13.0 0.1 0.096 11.8 0.0 1.5 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) PHD PF00628.24 KUM65032.1 - 6.2e-08 32.2 7.3 1.1e-07 31.3 5.1 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 KUM65032.1 - 0.0016 18.0 2.3 0.0033 17.1 1.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 Cytochrom_c3_2 PF14537.1 KUM65032.1 - 0.13 12.6 6.1 0.83 10.0 0.1 2.7 2 0 0 2 2 2 0 Cytochrome c3 US2 PF02476.10 KUM65032.1 - 1.6 9.2 5.7 0.32 11.4 0.1 2.6 3 0 0 3 3 3 0 US2 family PHD_2 PF13831.1 KUM65032.1 - 4.8 6.5 10.0 0.24 10.7 2.9 1.9 2 1 0 2 2 2 0 PHD-finger CoA_transf_3 PF02515.12 KUM65033.1 - 1.3e-59 200.6 0.0 2e-59 200.0 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III GxDLY PF14607.1 KUM65033.1 - 0.14 11.5 0.1 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 N-terminus of Esterase_SGNH_hydro-type Lum_binding PF00677.12 KUM65034.1 - 6.5e-35 118.9 0.1 1.2e-19 70.0 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain TRAM_LAG1_CLN8 PF03798.11 KUM65035.1 - 8.8e-52 175.5 15.3 8.8e-52 175.5 10.6 1.6 2 0 0 2 2 2 1 TLC domain SWIB PF02201.13 KUM65036.1 - 7.3e-16 57.6 0.0 1.4e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain PCI PF01399.22 KUM65037.1 - 2.9e-21 75.7 1.2 7.8e-21 74.3 0.1 2.3 2 1 0 2 2 2 1 PCI domain DDRGK PF09756.4 KUM65037.1 - 6.2e-05 22.4 0.5 0.00011 21.7 0.3 1.3 1 0 0 1 1 1 1 DDRGK domain TPR_8 PF13181.1 KUM65037.1 - 0.00028 20.4 8.0 9.3 6.3 0.0 5.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 KUM65037.1 - 0.00032 20.5 16.2 0.57 10.1 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat HTH_Crp_2 PF13545.1 KUM65037.1 - 0.0022 17.7 0.2 1.1 9.1 0.1 3.4 3 1 1 4 4 4 1 Crp-like helix-turn-helix domain PCI_Csn8 PF10075.4 KUM65037.1 - 0.023 14.4 0.4 0.055 13.2 0.3 1.6 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 TPR_14 PF13428.1 KUM65037.1 - 0.047 14.3 11.4 29 5.6 0.6 6.2 5 2 2 7 7 6 0 Tetratricopeptide repeat Prefoldin_2 PF01920.15 KUM65037.1 - 0.053 13.2 3.1 0.076 12.7 0.5 2.5 2 0 0 2 2 2 0 Prefoldin subunit Soyouz_module PF14313.1 KUM65037.1 - 0.053 13.0 0.1 0.32 10.5 0.0 2.4 3 0 0 3 3 3 0 N-terminal region of Paramyxovirinae phosphoprotein (P) TPR_2 PF07719.12 KUM65037.1 - 0.14 12.1 12.2 7.2 6.7 0.1 5.7 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 KUM65037.1 - 0.68 9.6 10.7 1.5 8.5 0.1 5.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 KUM65037.1 - 2.4 8.9 17.3 15 6.4 3.4 4.9 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KUM65037.1 - 6.8 7.3 8.1 58 4.4 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.27 KUM65038.1 - 3.8e-39 131.1 1.7 5.3e-09 35.6 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Sof1 PF04158.9 KUM65038.1 - 6.1e-29 99.8 13.9 1.4e-28 98.7 9.6 1.6 1 0 0 1 1 1 1 Sof1-like domain eIF2A PF08662.6 KUM65038.1 - 0.0002 21.1 0.8 0.0011 18.6 0.1 2.4 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 KUM65038.1 - 0.0062 14.8 0.0 0.022 13.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) Nup160 PF11715.3 KUM65038.1 - 0.049 11.7 6.4 0.16 10.0 0.1 3.4 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Pkinase PF00069.20 KUM65039.1 - 1.1e-70 237.8 0.0 1.5e-70 237.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM65039.1 - 1.3e-30 106.3 0.0 2e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KUM65039.1 - 3.6e-15 56.2 0.7 2.4e-14 53.5 0.5 2.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KUM65039.1 - 3.9e-09 35.8 0.1 1.1e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KUM65039.1 - 0.004 16.9 0.0 0.0076 16.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KUM65039.1 - 0.05 12.9 0.0 0.12 11.6 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 KUM65039.1 - 0.077 12.5 0.1 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase CRC_subunit PF08624.5 KUM65040.1 - 2e-56 189.7 0.0 2.9e-56 189.2 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit tRNA-synt_1c PF00749.16 KUM65041.1 - 1.1e-99 333.0 0.0 1.5e-99 332.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KUM65041.1 - 1.4e-31 109.5 0.0 5e-31 107.6 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain THUMP PF02926.12 KUM65041.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 THUMP domain F-box-like PF12937.2 KUM65042.1 - 0.0055 16.3 0.0 0.019 14.7 0.0 1.9 1 1 0 1 1 1 1 F-box-like DUF4027 PF13219.1 KUM65042.1 - 0.036 13.4 0.2 0.076 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) F-box PF00646.28 KUM65042.1 - 0.05 13.2 0.0 0.15 11.7 0.0 1.9 1 0 0 1 1 1 0 F-box domain TauD PF02668.11 KUM65043.1 - 1.1e-39 136.6 1.4 1.6e-39 136.1 1.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 KUM65043.1 - 7.7e-09 35.8 0.1 1.4e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF971) 2OG-FeII_Oxy_3 PF13640.1 KUM65043.1 - 0.00062 20.2 1.4 0.032 14.7 0.0 2.5 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily CsiD PF08943.5 KUM65043.1 - 0.027 13.3 0.1 0.079 11.8 0.1 1.8 1 1 0 1 1 1 0 CsiD DUF3331 PF11811.3 KUM65043.1 - 0.041 13.4 0.1 0.084 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3331) AAA PF00004.24 KUM65044.1 - 1.2e-40 138.7 0.0 2.4e-40 137.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KUM65044.1 - 3.4e-05 23.0 0.1 0.00011 21.2 0.0 1.9 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KUM65044.1 - 6.1e-05 22.7 0.0 0.00031 20.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KUM65044.1 - 0.00033 20.6 0.2 0.017 15.1 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KUM65044.1 - 0.0012 18.9 0.2 0.031 14.4 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KUM65044.1 - 0.0017 18.3 1.4 0.0096 15.8 0.0 2.9 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KUM65044.1 - 0.0027 16.6 0.0 0.0074 15.2 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF815) PhoH PF02562.11 KUM65044.1 - 0.0045 16.2 0.2 0.05 12.8 0.1 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 KUM65044.1 - 0.0068 15.5 0.0 0.018 14.2 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KUM65044.1 - 0.011 15.6 0.0 0.032 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KUM65044.1 - 0.013 15.2 0.3 0.031 14.0 0.2 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 KUM65044.1 - 0.024 14.0 0.1 0.051 12.9 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 KUM65044.1 - 0.036 13.4 0.9 0.49 9.7 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 KUM65044.1 - 0.039 13.5 0.1 0.14 11.7 0.1 2.0 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KUM65044.1 - 0.043 13.7 0.2 0.25 11.2 0.0 2.3 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 KUM65044.1 - 0.043 12.8 0.9 0.11 11.6 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 KUM65044.1 - 0.044 14.6 0.1 0.044 14.6 0.1 2.8 2 2 0 2 2 2 0 AAA domain AAA_11 PF13086.1 KUM65044.1 - 0.82 9.1 0.0 0.82 9.1 0.0 2.6 2 1 1 3 3 3 0 AAA domain Methyltransf_31 PF13847.1 KUM65045.1 - 2.9e-13 49.6 0.0 4.7e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM65045.1 - 2.2e-11 44.3 0.0 6.3e-11 42.8 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KUM65045.1 - 3.9e-11 43.0 0.0 1e-10 41.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 KUM65045.1 - 7.3e-11 41.7 0.0 1.1e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PRMT5 PF05185.11 KUM65045.1 - 1.1e-09 37.7 0.0 1.4e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_11 PF08241.7 KUM65045.1 - 7.6e-09 35.9 0.0 2.1e-08 34.5 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM65045.1 - 6.5e-07 29.2 0.0 4.2e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 KUM65045.1 - 2.3e-06 26.5 0.1 4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 KUM65045.1 - 1.1e-05 24.8 0.0 1.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KUM65045.1 - 2.8e-05 24.3 0.0 8.3e-05 22.8 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain CMAS PF02353.15 KUM65045.1 - 3.2e-05 23.1 0.0 4.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 KUM65045.1 - 0.0002 21.3 0.0 0.00058 19.8 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.7 KUM65045.1 - 0.00041 20.7 0.0 0.00081 19.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KUM65045.1 - 0.0027 17.1 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 KUM65045.1 - 0.012 14.7 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 KUM65045.1 - 0.017 14.7 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 KUM65045.1 - 0.019 14.5 0.2 0.032 13.7 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.9 KUM65045.1 - 0.025 13.7 0.0 0.05 12.7 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB UPF0020 PF01170.13 KUM65045.1 - 0.028 14.0 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Met_10 PF02475.11 KUM65045.1 - 0.048 13.2 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_24 PF13578.1 KUM65045.1 - 0.079 13.7 0.0 0.18 12.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 KUM65045.1 - 0.095 11.7 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MaoC_dehydratas PF01575.14 KUM65046.1 - 6.1e-23 80.5 0.0 1.1e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KUM65046.1 - 2.7e-08 33.6 0.0 1.2e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase PGM_PMM_I PF02878.11 KUM65047.1 - 9.4e-17 60.7 0.1 2.6e-07 30.2 0.0 2.9 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KUM65047.1 - 8.2e-16 58.2 0.5 6.3e-15 55.3 0.1 2.5 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KUM65047.1 - 5.9e-11 42.2 0.6 2.5e-10 40.2 0.2 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 KUM65047.1 - 0.00058 19.8 0.2 0.0024 17.8 0.1 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Per1 PF04080.8 KUM65048.1 - 2.6e-107 358.2 14.6 3.3e-107 357.9 10.1 1.1 1 0 0 1 1 1 1 Per1-like NmrA PF05368.8 KUM65049.1 - 1.5e-09 37.4 0.0 2.3e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KUM65049.1 - 1.3e-07 31.7 0.1 2.2e-07 31.0 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding Pescadillo_N PF06732.6 KUM65050.1 - 2.9e-115 384.3 0.0 2.9e-115 384.3 0.0 1.8 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 KUM65050.1 - 2.9e-07 30.5 0.0 3.2e-06 27.2 0.0 2.7 3 1 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain PIG-U PF06728.8 KUM65051.1 - 2.1e-123 411.9 24.2 2.4e-123 411.7 16.7 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Mannosyl_trans PF05007.8 KUM65051.1 - 4e-05 23.3 0.1 7.7e-05 22.4 0.1 1.5 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) Acetyltransf_1 PF00583.19 KUM65052.1 - 8.3e-17 60.9 0.1 1.3e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KUM65052.1 - 8.7e-06 25.4 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KUM65052.1 - 2.4e-05 24.4 0.1 7e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KUM65052.1 - 3.9e-05 23.7 0.1 6e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KUM65052.1 - 0.019 15.1 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KUM65052.1 - 0.024 14.4 0.1 0.093 12.5 0.1 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KUM65052.1 - 0.043 13.7 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyoxalase_2 PF12681.2 KUM65052.1 - 0.086 13.4 0.0 0.3 11.7 0.0 1.8 2 0 0 2 2 2 0 Glyoxalase-like domain Acetyltransf_CG PF14542.1 KUM65052.1 - 0.088 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase ADH_zinc_N PF00107.21 KUM65053.1 - 2e-28 98.5 0.3 3e-28 97.9 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KUM65053.1 - 2.6e-16 60.6 0.0 6.7e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM65053.1 - 1.4e-12 47.3 0.1 4.1e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 KUM65053.1 - 0.00068 19.6 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.16 KUM65053.1 - 0.0083 15.7 0.1 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Raffinose_syn PF05691.7 KUM65054.1 - 2.9e-51 173.9 3.1 8.2e-48 162.5 1.3 3.4 2 1 1 3 3 3 2 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 KUM65054.1 - 2.1e-06 26.6 0.2 3.4e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 Melibiase tRNA-synt_1b PF00579.20 KUM65055.1 - 7.6e-70 235.3 0.0 1e-69 234.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) MutS_V PF00488.16 KUM65056.1 - 8.3e-81 270.8 0.0 1.3e-80 270.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KUM65056.1 - 2.5e-51 174.3 0.0 4.6e-51 173.5 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KUM65056.1 - 5.2e-33 113.4 0.1 1.3e-32 112.1 0.0 1.7 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 KUM65056.1 - 1.7e-15 57.3 0.0 4.3e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 KUM65056.1 - 2.6e-14 53.1 0.3 5.4e-14 52.1 0.2 1.6 1 0 0 1 1 1 1 MutS family domain IV Shugoshin_C PF07557.6 KUM65056.1 - 0.015 14.7 0.9 0.039 13.4 0.6 1.7 1 0 0 1 1 1 0 Shugoshin C terminus AAA_29 PF13555.1 KUM65056.1 - 0.046 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 KUM65056.1 - 0.17 11.7 0.3 0.5 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Phe_tRNA-synt_N PF02912.13 KUM65057.1 - 0.11 12.1 0.6 0.27 10.9 0.2 1.7 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain DUF2981 PF11200.3 KUM65057.1 - 0.16 10.9 1.5 0.25 10.3 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) PaaSYMP PF14738.1 KUM65058.1 - 0.037 13.7 2.3 0.051 13.3 1.6 1.1 1 0 0 1 1 1 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 FYDLN_acid PF09538.5 KUM65058.1 - 0.12 12.9 7.7 0.17 12.4 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) RNA_pol_3_Rpc31 PF11705.3 KUM65058.1 - 0.24 11.3 6.2 0.28 11.1 4.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.9 KUM65058.1 - 0.62 8.0 4.5 0.59 8.1 3.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3306 PF11748.3 KUM65058.1 - 7.2 7.2 8.1 13 6.4 5.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) mRNA_triPase PF02940.10 KUM65059.1 - 2.8e-57 193.9 0.1 4.1e-57 193.3 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Acyl_transf_3 PF01757.17 KUM65060.1 - 8.7e-30 103.6 42.3 1.7e-29 102.7 29.3 1.5 1 1 0 1 1 1 1 Acyltransferase family Fungal_trans_2 PF11951.3 KUM65061.1 - 9.1e-09 34.3 0.1 0.00018 20.2 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain His_Phos_2 PF00328.17 KUM65064.1 - 4.7e-57 193.8 0.0 5.8e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) WD40 PF00400.27 KUM65065.1 - 5e-22 76.9 15.4 3.8e-08 32.9 0.0 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat CTP_transf_2 PF01467.21 KUM65066.1 - 1e-05 25.6 0.0 2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase FAD_syn PF06574.7 KUM65066.1 - 0.12 12.0 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 FAD synthetase Golgin_A5 PF09787.4 KUM65067.1 - 0.04 12.4 0.0 0.04 12.4 0.0 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 Myb_DNA-bind_6 PF13921.1 KUM65067.1 - 0.048 13.7 0.0 0.069 13.2 0.0 1.2 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF134 PF02001.11 KUM65067.1 - 0.17 11.8 0.8 0.31 10.9 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function DUF134 PQ-loop PF04193.9 KUM65069.1 - 1.6e-22 78.8 3.9 5.4e-11 41.8 0.8 2.8 2 0 0 2 2 2 2 PQ loop repeat DoxX_3 PF13781.1 KUM65069.1 - 0.16 12.3 3.4 0.1 12.9 0.7 2.0 2 0 0 2 2 2 0 DoxX-like family Med8 PF10232.4 KUM65070.1 - 1.5e-52 178.3 0.1 1.8e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Myc_N PF01056.13 KUM65070.1 - 0.025 13.7 0.1 0.041 13.0 0.1 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Med11 PF10280.4 KUM65070.1 - 0.094 12.7 1.4 0.11 12.4 0.3 1.6 2 0 0 2 2 2 0 Mediator complex protein DUF575 PF04746.7 KUM65071.1 - 0.062 13.3 0.2 0.18 11.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF575) TMEM154 PF15102.1 KUM65071.1 - 0.36 10.5 1.2 0.59 9.8 0.0 1.9 2 0 0 2 2 2 0 TMEM154 protein family RCR PF12273.3 KUM65071.1 - 0.47 11.0 28.1 0.026 15.0 7.2 2.4 1 1 1 2 2 2 0 Chitin synthesis regulation, resistance to Congo red PsbX PF06596.6 KUM65071.1 - 0.74 9.5 4.4 0.74 9.5 1.8 2.0 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) EphA2_TM PF14575.1 KUM65071.1 - 0.95 9.8 0.0 0.95 9.8 0.0 2.5 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain IncA PF04156.9 KUM65071.1 - 2.7 7.5 4.5 15 5.1 0.0 2.2 2 0 0 2 2 2 0 IncA protein EphA2_TM PF14575.1 KUM65074.1 - 0.024 15.0 0.3 0.14 12.6 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain CD34_antigen PF06365.7 KUM65074.1 - 0.19 11.3 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family PMI_typeI PF01238.16 KUM65075.1 - 6e-33 114.3 0.0 2.2e-31 109.1 0.0 2.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 KUM65075.1 - 5.6e-05 22.5 0.1 0.23 11.0 0.0 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 KUM65075.1 - 0.005 16.5 0.1 8.4 6.0 0.0 3.1 2 1 1 3 3 3 2 AraC-like ligand binding domain tRNA-synt_2 PF00152.15 KUM65077.1 - 1e-102 343.3 0.0 1.5e-102 342.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KUM65077.1 - 0.00012 21.8 0.0 0.00022 20.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 KUM65077.1 - 0.0015 18.1 0.0 0.0027 17.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ABC_tran PF00005.22 KUM65078.1 - 4.1e-47 159.9 0.0 4.5e-30 104.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KUM65078.1 - 1.4e-29 103.3 18.9 2.7e-18 66.3 7.5 3.3 4 1 0 4 4 3 2 ABC transporter transmembrane region SMC_N PF02463.14 KUM65078.1 - 2.4e-10 40.0 0.0 0.022 13.9 0.0 4.5 4 1 1 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KUM65078.1 - 0.00014 21.8 2.0 0.043 13.7 0.1 2.9 2 0 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 KUM65078.1 - 0.00018 20.5 0.0 0.16 10.8 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 KUM65078.1 - 0.00024 20.5 0.0 0.21 10.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KUM65078.1 - 0.0011 18.4 1.1 1.5 8.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 KUM65078.1 - 0.0021 18.0 0.4 8.2 6.2 0.0 4.0 3 1 1 4 4 4 1 AAA domain AAA_22 PF13401.1 KUM65078.1 - 0.0023 18.0 0.2 5.9 7.0 0.0 3.4 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.12 KUM65078.1 - 0.0025 17.6 1.1 0.64 9.7 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 KUM65078.1 - 0.0032 17.3 0.1 0.41 10.6 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.1 KUM65078.1 - 0.0048 17.2 1.2 0.2 11.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 KUM65078.1 - 0.0049 16.0 0.2 2.2 7.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 KUM65078.1 - 0.0071 15.8 3.2 1.2 8.5 0.0 3.4 3 1 0 4 4 4 1 AAA-like domain Miro PF08477.8 KUM65078.1 - 0.011 16.1 0.2 4.9 7.6 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein DUF2075 PF09848.4 KUM65078.1 - 0.023 13.6 0.3 0.26 10.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 KUM65078.1 - 0.085 12.3 0.0 12 5.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Viral_helicase1 PF01443.13 KUM65078.1 - 0.26 10.7 0.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase LigD_N PF13298.1 KUM65079.1 - 8.4e-29 99.7 0.0 3.1e-28 97.9 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase Ligase (LigD) FAD_binding_4 PF01565.18 KUM65080.1 - 5.8e-29 100.3 2.0 1.2e-28 99.3 1.4 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KUM65080.1 - 5.1e-12 45.5 0.0 1.3e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Macscav_rec PF03523.8 KUM65080.1 - 0.056 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Macrophage scavenger receptor Sulf_transp PF04143.9 KUM65081.1 - 3.1e-16 59.0 16.1 8.5e-11 41.7 3.7 4.4 5 0 0 5 5 5 2 Sulphur transport DUF4341 PF14241.1 KUM65081.1 - 1.2e-09 37.7 1.1 1.2e-09 37.7 0.8 3.0 4 0 0 4 4 4 1 Domain of unknown function (DUF4341) Peptidase_M28 PF04389.12 KUM65082.1 - 1.1e-33 116.5 0.0 1.5e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 UbiA PF01040.13 KUM65085.1 - 3.8e-28 98.4 18.0 5.5e-28 97.8 12.5 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family Cutinase PF01083.17 KUM65086.1 - 1.8e-46 158.0 2.0 2.3e-46 157.7 1.4 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KUM65086.1 - 0.0028 17.1 0.1 0.0043 16.4 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.11 KUM65086.1 - 0.0048 16.3 0.0 0.0098 15.3 0.0 1.5 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KUM65086.1 - 0.0056 16.4 0.2 0.0088 15.8 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family APH PF01636.18 KUM65087.1 - 3.5e-06 26.9 0.2 5.3e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family MFS_1 PF07690.11 KUM65088.1 - 8.8e-35 120.0 14.9 8.8e-35 120.0 10.4 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM65088.1 - 5.8e-10 38.3 6.4 5.8e-10 38.3 4.5 2.9 3 1 0 3 3 3 1 Sugar (and other) transporter DAO PF01266.19 KUM65089.1 - 5e-34 117.7 2.7 6.7e-34 117.3 1.9 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KUM65089.1 - 0.0025 17.7 0.1 0.0064 16.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KUM65089.1 - 0.0027 17.5 0.1 0.18 11.6 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KUM65089.1 - 0.0046 17.0 0.0 2.4 8.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KUM65089.1 - 0.038 12.9 0.0 0.25 10.2 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KUM65089.1 - 0.053 13.3 0.0 0.11 12.3 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KUM65089.1 - 0.67 8.9 2.8 3.7 6.4 0.1 3.0 4 0 0 4 4 4 0 FAD binding domain Amidase PF01425.16 KUM65090.1 - 7.3e-98 328.2 0.0 9.9e-98 327.8 0.0 1.2 1 0 0 1 1 1 1 Amidase CTD PF12815.2 KUM65091.1 - 4.3e-26 91.7 47.2 1.8e-23 83.2 19.9 3.9 1 1 2 3 3 3 3 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.3 KUM65091.1 - 4.9e-17 62.3 11.4 4.9e-17 62.3 7.9 3.5 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal Spt5-NGN PF03439.8 KUM65091.1 - 1e-16 60.4 0.0 1.7e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 KUM65091.1 - 7.5e-11 41.3 10.9 0.0047 16.6 0.0 4.0 4 0 0 4 4 4 3 KOW motif TFIIF_alpha PF05793.7 KUM65091.1 - 2.1 6.6 37.5 3.1 6.0 26.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ank_2 PF12796.2 KUM65092.1 - 0.0014 18.8 0.0 2.7 8.4 0.0 3.3 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KUM65092.1 - 0.0078 16.7 0.0 13 6.4 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeats (many copies) MiaE_2 PF13794.1 KUM65092.1 - 0.044 13.2 0.0 0.079 12.4 0.0 1.5 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like Acyl-CoA_dh_1 PF00441.19 KUM65093.1 - 1.1e-39 135.9 0.4 1.6e-39 135.4 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KUM65093.1 - 7.5e-20 70.1 0.1 1.4e-19 69.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 KUM65093.1 - 9.2e-19 67.0 0.2 1.7e-18 66.1 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 KUM65093.1 - 3.3e-18 66.2 0.0 7.4e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KUM65093.1 - 1.7e-06 28.3 0.0 2.6e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PC_rep PF01851.17 KUM65094.1 - 2.2e-37 125.2 22.5 1.4e-09 37.6 0.0 9.8 10 0 0 10 10 10 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KUM65094.1 - 3.7e-19 68.7 0.5 1.5e-12 47.6 0.0 5.3 2 1 3 5 5 5 4 HEAT repeats HEAT PF02985.17 KUM65094.1 - 7e-07 28.8 0.0 3.2 8.0 0.0 5.4 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 KUM65094.1 - 2.3e-06 27.9 6.6 3.7e-05 24.0 0.0 5.1 4 1 0 4 4 4 1 HEAT-like repeat HEAT_PBS PF03130.11 KUM65094.1 - 0.027 14.8 2.1 0.87 10.2 0.0 4.0 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat RICTOR_V PF14668.1 KUM65094.1 - 0.11 12.4 0.2 7.9 6.4 0.0 3.3 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 Atg14 PF10186.4 KUM65094.1 - 0.37 9.7 4.0 0.72 8.7 2.8 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Filament PF00038.16 KUM65095.1 - 0.0056 16.1 0.3 0.0056 16.1 0.2 1.8 2 0 0 2 2 2 1 Intermediate filament protein Fib_alpha PF08702.5 KUM65095.1 - 0.0067 16.5 0.7 0.021 14.9 0.5 1.8 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family DUF3189 PF11385.3 KUM65095.1 - 0.0068 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3189) TMF_TATA_bd PF12325.3 KUM65095.1 - 0.0075 15.9 3.6 0.81 9.4 0.9 2.6 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.17 KUM65095.1 - 0.022 14.7 3.5 0.044 13.7 1.2 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain NuA4 PF09340.5 KUM65095.1 - 0.06 12.9 0.4 0.2 11.2 0.3 1.9 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 Fez1 PF06818.10 KUM65095.1 - 0.068 13.1 5.2 0.17 11.9 3.6 1.6 1 1 0 1 1 1 0 Fez1 DUF1664 PF07889.7 KUM65095.1 - 0.084 12.6 2.0 0.29 10.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) IncA PF04156.9 KUM65095.1 - 0.098 12.2 5.1 0.074 12.6 2.0 1.8 2 0 0 2 2 2 0 IncA protein Reo_sigmaC PF04582.7 KUM65095.1 - 0.099 11.7 0.9 0.17 11.0 0.6 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein COG5 PF10392.4 KUM65095.1 - 0.79 9.6 5.5 0.52 10.2 1.6 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 CENP-H PF05837.7 KUM65095.1 - 1.2 9.3 6.2 0.49 10.5 2.1 2.0 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Abhydrolase_5 PF12695.2 KUM65096.1 - 6.5e-08 32.4 0.0 1.2e-07 31.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KUM65096.1 - 8.5e-07 29.0 0.0 2.9e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KUM65096.1 - 0.013 14.7 0.0 0.032 13.4 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF3336 PF11815.3 KUM65097.1 - 8.3e-43 145.3 2.9 1.5e-42 144.5 2.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KUM65097.1 - 1.2e-23 84.0 0.0 2.3e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Peptidase_M28 PF04389.12 KUM65100.1 - 2.2e-32 112.2 0.1 4e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KUM65100.1 - 9.4e-12 44.5 2.0 1.5e-11 43.9 0.8 1.8 2 0 0 2 2 2 1 PA domain Peptidase_M42 PF05343.9 KUM65100.1 - 0.0042 15.8 0.0 0.052 12.3 0.0 2.3 3 0 0 3 3 3 1 M42 glutamyl aminopeptidase Abhydrolase_6 PF12697.2 KUM65103.1 - 5e-25 88.7 6.7 2.3e-24 86.5 4.7 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KUM65103.1 - 7.1e-10 38.5 0.0 2.7e-09 36.7 0.0 2.1 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 KUM65103.1 - 1.6e-09 37.6 0.2 9.1e-09 35.2 0.2 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KUM65103.1 - 5.4e-09 35.9 1.0 9.9e-09 35.0 0.7 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KUM65103.1 - 9.4e-05 21.9 0.3 0.00083 18.8 0.2 2.0 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.4 KUM65103.1 - 0.0025 17.1 1.9 0.0031 16.7 0.8 1.5 1 1 0 1 1 1 1 Esterase PHB depolymerase Chlorophyllase2 PF12740.2 KUM65103.1 - 0.13 11.0 0.0 0.24 10.2 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme SRR1 PF07985.7 KUM65104.1 - 2.9e-14 52.7 0.0 5.3e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 SRR1 RRP7 PF12923.2 KUM65104.1 - 0.051 13.5 0.5 0.11 12.5 0.1 1.7 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) PNTB PF02233.11 KUM65106.1 - 2.3e-164 547.5 21.3 3.9e-164 546.8 14.8 1.4 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 KUM65106.1 - 1.8e-54 183.8 0.4 3.3e-54 182.9 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 KUM65106.1 - 3.3e-44 150.2 0.0 6.8e-44 149.1 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 KUM65106.1 - 1.9e-30 104.8 4.7 1.9e-30 104.8 3.2 4.5 3 1 0 4 4 4 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 KUM65106.1 - 2.9e-05 23.2 0.1 0.23 10.5 0.0 3.1 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 KUM65106.1 - 0.0081 15.7 0.1 0.035 13.6 0.1 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KUM65106.1 - 0.011 16.2 0.0 0.04 14.5 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KUM65106.1 - 0.014 15.0 0.0 0.042 13.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain TPP_enzyme_M PF00205.17 KUM65106.1 - 0.017 14.9 0.4 0.13 11.9 0.2 2.7 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Pyr_redox_2 PF07992.9 KUM65106.1 - 0.027 14.3 0.1 0.075 12.9 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM65106.1 - 0.37 10.8 2.9 0.41 10.7 0.3 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 KUM65106.1 - 7.4 6.6 8.8 9.4 6.3 0.0 3.8 6 0 0 6 6 5 0 Shikimate / quinate 5-dehydrogenase AA_permease_2 PF13520.1 KUM65107.1 - 1.8e-41 142.0 50.3 2.5e-41 141.6 34.8 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM65107.1 - 3.7e-16 58.5 40.0 5.5e-16 57.9 27.7 1.2 1 0 0 1 1 1 1 Amino acid permease DUF1546 PF07571.8 KUM65109.1 - 3e-34 117.0 0.0 7.5e-34 115.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 KUM65109.1 - 7.6e-24 83.4 0.0 2.9e-23 81.5 0.0 1.9 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 KUM65109.1 - 1.1e-07 31.8 0.4 3.3e-07 30.3 0.2 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KUM65109.1 - 0.045 13.8 0.8 0.11 12.6 0.1 2.0 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SAM_decarbox PF01536.11 KUM65110.1 - 2.3e-87 292.7 0.0 1.9e-86 289.7 0.0 2.2 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase TAFII28 PF04719.9 KUM65111.1 - 3.6e-19 68.3 0.1 7.3e-19 67.3 0.0 1.5 2 0 0 2 2 2 1 hTAFII28-like protein conserved region DUF2849 PF11011.3 KUM65111.1 - 1.8 8.8 8.3 2.2 8.5 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2849) IPP-2 PF04979.9 KUM65113.1 - 9.3e-08 32.3 18.8 6e-07 29.7 1.7 2.8 1 1 1 3 3 3 2 Protein phosphatase inhibitor 2 (IPP-2) MFS_1 PF07690.11 KUM65114.1 - 3.6e-31 108.1 34.1 2e-27 95.8 17.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 KUM65114.1 - 0.00033 18.9 3.3 0.00033 18.9 2.3 2.8 3 0 0 3 3 3 1 Transmembrane secretion effector MFS_2 PF13347.1 KUM65114.1 - 0.0031 15.9 10.8 0.0031 15.9 7.5 3.0 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 KUM65114.1 - 0.013 15.3 4.7 0.04 13.7 0.1 3.0 3 0 0 3 3 3 0 MFS_1 like family Folate_carrier PF01770.13 KUM65114.1 - 0.41 9.1 8.9 0.44 8.9 0.6 2.5 3 0 0 3 3 3 0 Reduced folate carrier CRAL_TRIO PF00650.15 KUM65115.1 - 8e-16 57.9 0.0 1.1e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KUM65115.1 - 0.00038 20.5 0.0 0.0014 18.7 0.0 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Prok_Ub PF14454.1 KUM65115.1 - 0.044 13.4 0.0 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 Prokaryotic Ubiquitin Acyl_transf_3 PF01757.17 KUM65116.1 - 5.2e-19 68.2 27.3 1.2e-18 67.1 18.9 1.7 1 1 0 1 1 1 1 Acyltransferase family 60KD_IMP PF02096.15 KUM65117.1 - 1.5e-38 132.4 2.5 1.5e-38 132.4 1.7 1.8 2 0 0 2 2 2 1 60Kd inner membrane protein MARVEL PF01284.18 KUM65120.1 - 3.8e-08 33.2 1.5 3.8e-08 33.2 1.0 1.7 2 0 0 2 2 2 1 Membrane-associating domain VIT1 PF01988.14 KUM65120.1 - 0.067 12.6 0.9 0.078 12.4 0.6 1.4 1 1 0 1 1 1 0 VIT family DUF1195 PF06708.6 KUM65120.1 - 0.086 12.2 0.8 0.14 11.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) UPF0233 PF06781.7 KUM65120.1 - 2.1 8.0 6.5 3.1 7.4 0.1 3.3 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0233) eIF-5a PF01287.15 KUM65123.1 - 0.0033 17.3 0.0 0.0068 16.3 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold SelP_N PF04592.9 KUM65123.1 - 0.24 10.7 5.5 0.025 13.9 0.6 1.6 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Amidase PF01425.16 KUM65124.1 - 0.00016 20.7 0.0 0.00017 20.6 0.0 1.0 1 0 0 1 1 1 1 Amidase PHD PF00628.24 KUM65126.1 - 2.8e-09 36.5 1.6 6.2e-09 35.4 1.1 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KUM65126.1 - 0.063 12.5 1.9 0.1 11.9 1.3 1.3 1 0 0 1 1 1 0 PHD-finger ELO PF01151.13 KUM65128.1 - 2.9e-61 206.9 23.3 3.4e-61 206.7 16.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family tRNA-synt_1b PF00579.20 KUM65129.1 - 1.5e-54 185.0 0.0 1.9e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) MFS_1 PF07690.11 KUM65130.1 - 2.8e-43 148.0 29.4 2.8e-43 148.0 20.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM65130.1 - 4.1e-10 38.5 2.0 7.1e-10 37.7 1.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KUM65130.1 - 4.7e-08 32.0 28.5 6e-07 28.3 19.5 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3169 PF11368.3 KUM65130.1 - 0.046 12.9 0.0 3.6 6.7 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3169) DUF2178 PF09946.4 KUM65130.1 - 1.3 8.8 6.1 0.21 11.3 0.3 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2178) GATase_5 PF13507.1 KUM65131.1 - 1.5e-95 319.0 0.0 2.3e-95 318.3 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 KUM65131.1 - 2.5e-42 144.4 0.3 1.7e-20 73.5 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 KUM65131.1 - 5e-27 93.9 0.0 1.8e-26 92.1 0.0 2.1 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain TOM13 PF08219.6 KUM65132.1 - 3e-31 107.0 0.0 3.8e-31 106.6 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 COX5A PF02284.11 KUM65133.1 - 1.7e-37 127.6 0.2 2.3e-37 127.2 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Glyco_transf_15 PF01793.11 KUM65134.1 - 1.3e-136 454.8 7.2 1.6e-136 454.6 5.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_25 PF01755.12 KUM65134.1 - 0.012 15.3 0.4 0.016 14.8 0.3 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Spc97_Spc98 PF04130.8 KUM65135.1 - 4.4e-73 246.4 4.4 4.4e-73 246.4 3.0 1.5 2 0 0 2 2 2 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 KUM65135.1 - 3.1e-13 48.7 0.0 7.2e-13 47.5 0.0 1.6 2 0 0 2 2 2 1 gamma-Tubulin ring complex non-core subunit mod21 FANCI_S1-cap PF14674.1 KUM65135.1 - 0.79 9.8 3.1 0.49 10.4 0.2 2.2 2 0 0 2 2 2 0 FANCI solenoid 1 cap TB2_DP1_HVA22 PF03134.14 KUM65138.1 - 1.7e-30 104.6 8.3 2.5e-30 104.0 5.7 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Caps_synth_CapC PF14102.1 KUM65138.1 - 0.12 12.5 4.3 0.18 11.8 3.0 1.3 1 0 0 1 1 1 0 Capsule biosynthesis CapC Ras PF00071.17 KUM65139.1 - 9.1e-52 174.7 0.0 1.1e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KUM65139.1 - 7.1e-21 74.9 0.0 1.2e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KUM65139.1 - 5.1e-10 38.8 0.0 5.5e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KUM65139.1 - 2.8e-06 26.8 0.0 2.6e-05 23.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KUM65139.1 - 1.2e-05 25.2 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KUM65139.1 - 0.0014 18.7 0.4 0.022 14.9 0.2 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KUM65139.1 - 0.056 13.4 0.5 0.51 10.2 0.1 2.2 1 1 1 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 KUM65139.1 - 0.13 11.6 0.1 0.42 9.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain Peroxin-3 PF04882.7 KUM65140.1 - 1.4e-149 498.4 0.0 1.7e-149 498.2 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 DUF1649 PF07855.7 KUM65141.1 - 8.6e-63 210.8 0.0 9.8e-63 210.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) CAF1A PF12253.3 KUM65142.1 - 2.4e-23 82.0 6.8 2.4e-23 82.0 4.7 4.0 2 1 1 3 3 3 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 KUM65142.1 - 1e-13 51.2 78.7 2.7e-13 49.7 54.5 1.8 1 1 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Borrelia_P83 PF05262.6 KUM65142.1 - 0.0038 15.5 31.8 0.0048 15.2 22.1 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein THOC7 PF05615.8 KUM65144.1 - 1.6e-37 128.8 7.7 1.6e-37 128.8 5.3 1.7 2 0 0 2 2 2 1 Tho complex subunit 7 CHASE3 PF05227.8 KUM65144.1 - 0.0094 15.6 6.2 0.0094 15.6 4.3 2.5 1 1 1 2 2 2 1 CHASE3 domain zf-C4H2 PF10146.4 KUM65144.1 - 0.02 14.8 8.1 0.056 13.4 1.5 2.3 1 1 0 2 2 2 0 Zinc finger-containing protein DUF4600 PF15372.1 KUM65144.1 - 0.15 12.2 9.7 0.27 11.4 6.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) FUSC PF04632.7 KUM65144.1 - 0.77 8.1 5.5 0.98 7.7 3.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family TBCA PF02970.11 KUM65145.1 - 5.3e-25 87.3 9.6 8.2e-25 86.7 6.7 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor A PhaP_Bmeg PF09602.5 KUM65145.1 - 0.027 14.3 2.6 0.049 13.4 1.8 1.5 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Prominin PF05478.6 KUM65145.1 - 0.029 11.9 5.6 0.032 11.7 3.9 1.0 1 0 0 1 1 1 0 Prominin Uso1_p115_C PF04871.8 KUM65145.1 - 0.075 12.9 8.8 0.071 13.0 5.4 1.5 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Aida_N PF08910.5 KUM65145.1 - 0.12 12.5 1.6 0.26 11.5 1.1 1.6 1 1 0 1 1 1 0 Aida N-terminus CENP-Q PF13094.1 KUM65145.1 - 0.13 12.2 11.8 0.55 10.2 8.2 1.8 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Fib_alpha PF08702.5 KUM65145.1 - 0.33 11.0 7.2 0.38 10.8 4.6 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family LMBR1 PF04791.11 KUM65145.1 - 0.57 8.7 2.5 0.58 8.6 1.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-C4H2 PF10146.4 KUM65145.1 - 1 9.3 7.2 1.2 9.1 5.0 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein IncA PF04156.9 KUM65145.1 - 1.2 8.7 7.2 1.3 8.5 5.0 1.1 1 0 0 1 1 1 0 IncA protein Elongin_A PF06881.6 KUM65146.1 - 9.9e-27 93.4 0.1 1.8e-26 92.6 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A MFS_1 PF07690.11 KUM65147.1 - 1.8e-09 36.8 14.9 1.8e-09 36.8 10.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.10 KUM65147.1 - 0.02 13.6 5.8 0.031 12.9 4.0 1.3 1 0 0 1 1 1 0 PUCC protein HOK_GEF PF01848.11 KUM65147.1 - 0.079 12.2 1.4 3.4 7.0 0.7 2.7 2 0 0 2 2 2 0 Hok/gef family Zip PF02535.17 KUM65147.1 - 4.2 6.2 9.1 5 6.0 4.9 1.9 1 1 1 2 2 2 0 ZIP Zinc transporter TRI12 PF06609.8 KUM65148.1 - 2.4e-07 29.3 10.0 3e-07 29.0 7.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KUM65148.1 - 4e-07 29.0 14.1 4e-07 29.0 9.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Pox_A14 PF05767.7 KUM65148.1 - 0.41 10.6 3.3 0.26 11.2 0.5 2.0 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 APH PF01636.18 KUM65150.1 - 6.1e-12 45.7 0.1 1.4e-11 44.6 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Acetyltransf_1 PF00583.19 KUM65150.1 - 8.3e-06 25.7 0.1 1.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KUM65150.1 - 0.00083 19.4 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KUM65150.1 - 0.008 16.2 0.1 0.027 14.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Choline_kinase PF01633.15 KUM65150.1 - 0.044 13.3 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DAO PF01266.19 KUM65151.1 - 3.3e-65 220.3 0.4 4.9e-65 219.7 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T PF01571.16 KUM65151.1 - 2.2e-55 187.3 0.0 3.4e-55 186.6 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KUM65151.1 - 6e-16 58.2 0.0 1.4e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pyr_redox_3 PF13738.1 KUM65151.1 - 2.4e-06 27.7 0.0 3.5e-05 23.9 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KUM65151.1 - 0.00022 21.5 1.5 0.011 16.1 0.0 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KUM65151.1 - 0.0015 18.5 0.2 0.007 16.3 0.1 2.1 3 0 0 3 3 2 1 TrkA-N domain ThiF PF00899.16 KUM65151.1 - 0.0039 17.0 0.1 0.0081 15.9 0.1 1.5 1 0 0 1 1 1 1 ThiF family SoxG PF04268.7 KUM65151.1 - 0.0051 16.6 0.0 0.029 14.2 0.0 2.2 1 1 0 2 2 2 1 Sarcosine oxidase, gamma subunit family NAD_binding_8 PF13450.1 KUM65151.1 - 0.017 15.1 0.0 0.066 13.2 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KUM65151.1 - 0.021 14.5 0.1 0.17 11.6 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KUM65151.1 - 0.037 13.0 0.5 0.37 9.7 0.4 2.1 1 1 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 KUM65151.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KUM65151.1 - 0.054 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase WD40 PF00400.27 KUM65154.1 - 3.2e-48 159.9 28.0 4.4e-09 35.8 1.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KUM65154.1 - 0.002 17.8 0.2 0.39 10.3 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Bacteroid_pep PF14406.1 KUM65154.1 - 0.14 12.3 0.0 0.5 10.5 0.0 2.0 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Bacteroidetes MBOAT PF03062.14 KUM65155.1 - 4e-23 82.0 17.5 8e-23 81.0 12.1 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 KUM65155.1 - 0.022 14.8 3.1 0.068 13.2 2.2 1.8 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family PseudoU_synth_1 PF01416.15 KUM65156.1 - 4.6e-22 78.4 0.1 8.9e-10 38.9 0.0 2.7 2 0 0 2 2 2 2 tRNA pseudouridine synthase Hexapep PF00132.19 KUM65157.1 - 2.1e-14 52.2 8.0 7.4e-12 44.2 2.8 3.3 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KUM65157.1 - 5.5e-14 51.4 7.6 7.5e-11 41.4 2.5 3.2 3 0 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 KUM65157.1 - 2.6e-12 46.5 0.1 4.3e-12 45.8 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase ICMT PF04140.9 KUM65158.1 - 3.2e-28 97.7 0.5 5.7e-28 96.9 0.4 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KUM65158.1 - 2.6e-12 46.7 2.5 2.6e-12 46.7 1.7 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 KUM65158.1 - 9.1e-08 31.6 0.5 1.2e-07 31.2 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF2721 PF11026.3 KUM65158.1 - 9.7 5.8 9.7 12 5.5 0.6 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2721) O-ag_pol_Wzy PF14296.1 KUM65160.1 - 0.038 12.5 0.1 0.046 12.2 0.1 1.0 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy DUF202 PF02656.10 KUM65161.1 - 8.4e-15 54.7 0.7 8.4e-15 54.7 0.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) OMPdecase PF00215.19 KUM65163.1 - 1.1e-77 260.5 0.0 1.4e-77 260.1 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family PGK PF00162.14 KUM65163.1 - 0.061 11.8 0.0 0.078 11.5 0.0 1.1 1 0 0 1 1 1 0 Phosphoglycerate kinase DUF72 PF01904.13 KUM65163.1 - 0.071 12.8 0.0 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF72 MAPEG PF01124.13 KUM65164.1 - 2.1e-27 95.2 0.4 2.5e-27 95.0 0.3 1.0 1 0 0 1 1 1 1 MAPEG family DUF2613 PF11021.3 KUM65164.1 - 0.13 11.9 3.4 0.24 11.1 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) DnaJ PF00226.26 KUM65165.1 - 2.5e-24 84.8 2.2 3.9e-24 84.1 1.5 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KUM65165.1 - 1.7e-16 60.0 15.6 2.8e-16 59.2 10.8 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 KUM65165.1 - 4.7e-10 39.2 0.0 1.9e-08 34.0 0.0 2.7 3 0 0 3 3 3 1 DnaJ C terminal domain HypA PF01155.14 KUM65165.1 - 0.27 10.9 8.3 1 9.0 0.5 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Lar_restr_allev PF14354.1 KUM65165.1 - 6.3 7.1 8.8 7 7.0 0.1 3.0 1 1 1 2 2 2 0 Restriction alleviation protein Lar ketoacyl-synt PF00109.21 KUM65166.1 - 3.9e-69 232.9 0.0 2.6e-68 230.2 0.0 2.4 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KUM65166.1 - 1.7e-59 200.4 0.0 4.1e-59 199.2 0.0 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 KUM65166.1 - 7.6e-55 186.1 0.0 1.6e-54 185.1 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KUM65166.1 - 3.5e-49 167.8 0.0 6.3e-49 167.0 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 KUM65166.1 - 1.2e-43 148.8 0.0 3.3e-43 147.4 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KUM65166.1 - 2.2e-35 121.0 0.0 5.1e-35 119.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KUM65166.1 - 1.5e-19 70.3 0.0 1.6e-18 66.9 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM65166.1 - 2.3e-14 53.4 0.0 6.1e-14 52.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KUM65166.1 - 1.2e-10 41.0 0.0 3.7e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 KUM65166.1 - 1.5e-10 40.8 0.0 6.4e-10 38.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM65166.1 - 3.5e-10 40.4 0.0 2.6e-09 37.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM65166.1 - 3.6e-07 30.5 0.0 1.2e-06 28.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KUM65166.1 - 7.8e-06 26.0 0.1 1.9e-05 24.8 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site NodS PF05401.6 KUM65166.1 - 1.5e-05 24.5 0.0 3.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_25 PF13649.1 KUM65166.1 - 6e-05 23.3 0.0 0.00022 21.5 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KUM65166.1 - 0.0002 20.5 0.0 0.00042 19.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 KUM65166.1 - 0.00042 19.3 0.0 0.00088 18.3 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 KUM65166.1 - 0.022 14.2 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase ADH_N PF08240.7 KUM65166.1 - 0.035 13.8 0.1 0.11 12.3 0.1 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Methyltransf_28 PF02636.12 KUM65166.1 - 0.048 13.0 0.0 0.24 10.7 0.0 2.0 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NNMT_PNMT_TEMT PF01234.12 KUM65166.1 - 0.35 9.8 0.0 2.9 6.7 0.0 2.1 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Clr5 PF14420.1 KUM65167.1 - 5.3e-08 32.6 0.2 1.4e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 Clr5 domain HTH_32 PF13565.1 KUM65167.1 - 1.9e-05 25.3 0.7 0.015 16.0 0.0 3.8 4 0 0 4 4 4 1 Homeodomain-like domain Sigma54_DBD PF04552.8 KUM65167.1 - 0.00018 21.0 0.3 0.011 15.2 0.0 2.3 1 1 1 2 2 2 1 Sigma-54, DNA binding domain rve PF00665.21 KUM65167.1 - 0.00055 20.0 0.4 0.2 11.7 0.0 2.6 2 1 0 2 2 2 1 Integrase core domain Arg_repressor PF01316.16 KUM65167.1 - 0.011 15.2 0.7 1.3 8.5 0.0 2.5 1 1 1 2 2 2 0 Arginine repressor, DNA binding domain HTH_12 PF08461.5 KUM65167.1 - 0.016 14.9 0.1 4.1 7.2 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain HTH_29 PF13551.1 KUM65167.1 - 0.029 14.5 0.6 0.5 10.5 0.0 3.2 4 0 0 4 4 4 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.13 KUM65167.1 - 0.039 13.9 3.9 1 9.4 0.1 3.2 3 0 0 3 3 3 0 Transposase DUF416 PF04222.7 KUM65167.1 - 0.043 12.9 0.1 0.095 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF416) SapB_2 PF03489.12 KUM65167.1 - 0.08 12.9 0.1 0.35 10.9 0.0 2.1 2 0 0 2 2 2 0 Saposin-like type B, region 2 DUF2067 PF09840.4 KUM65167.1 - 0.14 11.6 0.2 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) Phage_int_SAM_2 PF12834.2 KUM65167.1 - 0.57 10.5 4.8 13 6.2 0.2 3.5 3 0 0 3 3 3 0 Phage integrase, N-terminal HTH_21 PF13276.1 KUM65167.1 - 0.74 9.8 7.6 1.5 8.8 0.2 3.4 2 1 1 3 3 3 0 HTH-like domain S4 PF01479.20 KUM65168.1 - 6.1e-14 51.1 0.0 1.1e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.14 KUM65168.1 - 2.6e-06 27.7 3.0 4.1e-06 27.0 2.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Occludin_ELL PF07303.8 KUM65168.1 - 0.0099 16.5 0.1 0.025 15.3 0.1 1.6 1 0 0 1 1 1 1 Occludin homology domain COG2 PF06148.6 KUM65168.1 - 0.058 13.2 0.2 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ADH_zinc_N PF00107.21 KUM65170.1 - 4e-11 42.5 0.0 8.4e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM65170.1 - 2.8e-10 39.9 0.0 2.5e-09 36.8 0.0 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KUM65170.1 - 2.7e-09 37.9 0.0 5e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KUM65170.1 - 0.0066 16.0 0.1 0.016 14.7 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 KUM65170.1 - 0.074 13.0 0.0 0.18 11.8 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain SnoaL_2 PF12680.2 KUM65171.1 - 6.3e-05 23.3 0.2 0.0001 22.6 0.1 1.5 1 1 0 1 1 1 1 SnoaL-like domain DUF2358 PF10184.4 KUM65171.1 - 0.018 14.9 0.2 0.028 14.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) SnoaL PF07366.7 KUM65171.1 - 0.093 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase MFS_1 PF07690.11 KUM65172.1 - 4.3e-39 134.2 22.9 8.8e-39 133.1 14.6 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily PIRT PF15099.1 KUM65172.1 - 0.092 11.9 5.1 0.13 11.5 0.5 2.5 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family MFS_1_like PF12832.2 KUM65172.1 - 0.49 10.2 4.3 0.42 10.4 0.3 2.7 2 0 0 2 2 2 0 MFS_1 like family NfeD PF01957.13 KUM65172.1 - 2.1 8.4 13.0 6 7.0 0.0 3.9 3 1 1 4 4 4 0 NfeD-like C-terminal, partner-binding DUF4449 PF14613.1 KUM65173.1 - 0.001 19.0 2.8 0.0016 18.4 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Tricorn_C1 PF14684.1 KUM65173.1 - 0.0022 17.8 0.1 0.027 14.3 0.0 2.7 3 0 0 3 3 3 1 Tricorn protease C1 domain Beta-lactamase PF00144.19 KUM65174.1 - 1.9e-60 204.6 0.0 2.7e-60 204.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 KUM65174.1 - 1.5e-06 27.9 0.0 2.7e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Fungal_trans PF04082.13 KUM65175.1 - 1.2e-32 112.8 0.9 2e-32 112.1 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 KUM65176.1 - 4.9e-17 62.3 0.1 7.1e-17 61.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM65176.1 - 2.4e-07 30.7 0.0 3.4e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DBD_Tnp_Mut PF03108.10 KUM65177.1 - 1.1e-11 44.1 1.1 2e-11 43.2 0.8 1.4 1 0 0 1 1 1 1 MuDR family transposase MFS_1 PF07690.11 KUM65178.1 - 1.9e-48 165.0 45.1 5e-46 157.0 32.5 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM65178.1 - 2.3e-15 55.8 22.7 7.9e-15 54.0 15.7 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KUM65178.1 - 2.9e-11 42.6 11.4 2.9e-11 42.6 7.9 3.1 3 0 0 3 3 3 1 Sugar (and other) transporter DUF4094 PF13334.1 KUM65178.1 - 0.095 13.0 0.0 0.28 11.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Oxidored_FMN PF00724.15 KUM65179.1 - 4e-52 177.3 0.0 5.6e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.19 KUM65179.1 - 6.9e-05 22.2 0.0 0.047 12.9 0.0 2.4 1 1 1 2 2 2 2 Xylose isomerase-like TIM barrel Malic_M PF03949.10 KUM65180.1 - 1.2e-83 280.5 0.0 1.5e-83 280.2 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KUM65180.1 - 3e-63 212.6 0.0 8.3e-63 211.2 0.0 1.7 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain Fungal_trans PF04082.13 KUM65181.1 - 4.3e-30 104.4 0.2 9.5e-30 103.3 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM65181.1 - 2.9e-07 30.2 7.2 6.8e-07 29.0 5.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HLH PF00010.21 KUM65182.1 - 0.017 14.8 0.3 0.038 13.7 0.2 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Ank_2 PF12796.2 KUM65183.1 - 1.5e-64 214.3 0.3 9.1e-18 64.3 0.0 5.0 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KUM65183.1 - 2.3e-56 184.9 9.4 4.9e-08 32.4 0.1 10.8 10 0 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.1 KUM65183.1 - 2.2e-45 152.2 7.4 3.8e-10 39.9 0.0 8.4 4 2 5 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM65183.1 - 7.1e-43 140.3 3.9 5.8e-05 22.9 0.0 11.2 11 0 0 11 11 11 8 Ankyrin repeat Ank_5 PF13857.1 KUM65183.1 - 7.3e-39 130.9 12.9 6.3e-09 35.7 0.1 8.0 3 3 6 9 9 9 8 Ankyrin repeats (many copies) NACHT PF05729.7 KUM65183.1 - 2e-07 30.8 0.0 5e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KUM65183.1 - 0.00015 21.8 0.1 0.0008 19.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain DEP PF00610.16 KUM65183.1 - 0.01 15.5 0.1 5.3 6.8 0.0 3.2 3 0 0 3 3 3 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Hydrolase_4 PF12146.3 KUM65183.1 - 0.035 13.9 0.1 3.1 7.7 0.1 2.5 2 0 0 2 2 2 0 Putative lysophospholipase DUF2384 PF09722.5 KUM65183.1 - 0.036 13.9 0.0 1.3 8.9 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2384) AAA PF00004.24 KUM65183.1 - 0.047 13.8 0.0 0.25 11.5 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) C1_3 PF07649.7 KUM65183.1 - 0.062 13.3 11.1 0.13 12.3 7.7 1.6 1 0 0 1 1 1 0 C1-like domain NAD_binding_6 PF08030.7 KUM65183.1 - 0.099 12.5 0.1 0.41 10.5 0.0 2.1 2 0 0 2 2 1 0 Ferric reductase NAD binding domain zf-UDP PF14569.1 KUM65183.1 - 0.35 10.6 3.6 0.75 9.5 2.5 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger ZZ PF00569.12 KUM65183.1 - 1.2 8.7 9.3 2.7 7.6 6.5 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type Acyl_transf_3 PF01757.17 KUM65184.1 - 2.1e-20 72.8 26.2 7.1e-20 71.1 18.2 1.8 1 1 0 1 1 1 1 Acyltransferase family Lipase_GDSL_2 PF13472.1 KUM65186.1 - 1.1e-09 38.6 0.0 1.8e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 KUM65186.1 - 0.00097 18.9 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KUM65186.1 - 0.0019 18.0 0.1 0.003 17.4 0.1 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase p450 PF00067.17 KUM65187.1 - 8.6e-58 195.9 0.0 1.2e-57 195.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UDP-g_GGTase PF06427.6 KUM65187.1 - 0.0088 15.3 0.1 0.016 14.4 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase DRAT PF07357.6 KUM65187.1 - 0.037 13.2 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) TFIIE_alpha PF02002.12 KUM65188.1 - 5.6e-16 57.9 0.0 1.2e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit TEX19 PF15553.1 KUM65188.1 - 4.9 6.9 6.1 5 6.9 0.4 2.3 2 0 0 2 2 2 0 Testis-expressed protein 19 DUF3517 PF12030.3 KUM65189.1 - 1.4e-95 319.7 0.0 2.6e-95 318.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.24 KUM65189.1 - 1.2e-45 155.7 0.2 2.1e-45 154.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KUM65189.1 - 3.2e-17 62.9 0.1 7.6e-17 61.6 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PP2C_C PF07830.8 KUM65189.1 - 0.048 13.7 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain SpoIIIAH PF12685.2 KUM65189.1 - 1 8.8 1.6 1.1 8.6 0.1 1.8 2 0 0 2 2 2 0 SpoIIIAH-like protein Tyrosinase PF00264.15 KUM65190.1 - 2.2e-45 155.5 0.3 2.7e-45 155.2 0.2 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase PhrC_PhrF PF11131.3 KUM65191.1 - 0.043 13.4 0.6 0.36 10.4 0.4 2.6 1 0 0 1 1 1 0 Rap-phr extracellular signalling FAM196 PF15265.1 KUM65191.1 - 0.14 11.3 26.3 0.15 11.2 18.2 1.0 1 0 0 1 1 1 0 FAM196 family CytochromB561_N PF09786.4 KUM65191.1 - 0.16 10.3 26.5 0.2 10.0 18.4 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF605 PF04652.11 KUM65191.1 - 0.57 9.5 29.9 0.7 9.2 20.7 1.1 1 0 0 1 1 1 0 Vta1 like Utp14 PF04615.8 KUM65191.1 - 1.1 7.3 14.1 1.3 7.1 9.8 1.0 1 0 0 1 1 1 0 Utp14 protein DUF936 PF06075.7 KUM65191.1 - 2.8 6.7 24.1 3.2 6.5 16.7 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) AvrE PF11725.3 KUM65191.1 - 3.4 4.5 24.4 4 4.3 16.9 1.0 1 0 0 1 1 1 0 Pathogenicity factor KIAA1328 PF15369.1 KUM65191.1 - 5.1 6.8 19.3 6.8 6.4 13.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 Macoilin PF09726.4 KUM65191.1 - 5.1 5.2 31.3 6.3 4.9 21.7 1.1 1 0 0 1 1 1 0 Transmembrane protein VCBS PF13517.1 KUM65192.1 - 3.2e-31 107.4 39.2 4.1e-12 46.2 1.4 8.5 5 2 3 8 8 8 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.1 KUM65192.1 - 5.3e-14 52.7 0.3 1.2e-13 51.6 0.2 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family FG-GAP PF01839.18 KUM65192.1 - 1.7e-13 49.7 36.4 0.00043 19.8 0.1 7.1 7 0 0 7 7 7 4 FG-GAP repeat Lipase_GDSL PF00657.17 KUM65192.1 - 1.1e-12 48.2 0.3 2.8e-12 46.9 0.0 1.9 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.3 KUM65192.1 - 8e-10 38.4 12.7 0.02 14.3 0.0 6.6 5 2 1 7 7 7 4 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_3 PF14606.1 KUM65192.1 - 0.041 13.6 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Glyco_hydro_72 PF03198.9 KUM65193.1 - 1.1e-133 445.1 3.7 1.3e-133 444.8 2.6 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 KUM65193.1 - 2.1e-05 23.9 0.5 0.028 13.6 0.1 2.3 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 KUM65193.1 - 0.0026 16.6 0.1 0.0049 15.8 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Hydantoinase_B PF02538.9 KUM65196.1 - 3.1e-36 124.7 0.0 3.6e-36 124.4 0.0 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase SMC_N PF02463.14 KUM65197.1 - 8.8e-63 211.4 29.2 2.2e-61 206.9 20.2 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KUM65197.1 - 1.4e-21 76.6 6.0 2.9e-21 75.6 0.3 3.3 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KUM65197.1 - 2.4e-14 53.9 6.1 4.6e-06 26.8 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KUM65197.1 - 8.2e-05 22.0 0.0 0.0002 20.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 KUM65197.1 - 0.00094 18.4 34.1 0.17 11.0 3.3 5.5 3 2 3 6 6 6 3 Reovirus sigma C capsid protein Methyltransf_31 PF13847.1 KUM65198.1 - 3.9e-13 49.2 0.0 5.8e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KUM65198.1 - 5.3e-12 45.3 0.0 8.3e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KUM65198.1 - 8.6e-12 45.3 0.0 1.5e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM65198.1 - 1.8e-08 34.6 0.0 3.2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM65198.1 - 2.3e-08 34.4 0.0 3.6e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KUM65198.1 - 6.4e-08 32.6 0.0 3.6e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM65198.1 - 1.3e-05 24.9 0.0 1.9e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM65198.1 - 0.00051 20.5 0.0 0.0009 19.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KUM65198.1 - 0.0019 17.6 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 KUM65198.1 - 0.015 14.9 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GDI PF00996.13 KUM65199.1 - 7.7e-181 601.1 0.0 9.3e-181 600.9 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 KUM65199.1 - 0.048 13.6 0.0 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain 4HBT PF03061.17 KUM65200.1 - 2.6e-12 46.6 0.0 4e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 KUM65200.1 - 0.036 14.5 0.0 0.056 13.8 0.0 1.5 1 1 0 1 1 1 0 Thioesterase-like superfamily Bac_rhodopsin PF01036.13 KUM65203.1 - 1e-16 60.9 16.1 1.3e-16 60.5 11.1 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein 60KD_IMP PF02096.15 KUM65203.1 - 1.2 8.7 4.0 2.8 7.5 2.0 1.9 2 0 0 2 2 2 0 60Kd inner membrane protein ORC4_C PF14629.1 KUM65204.1 - 3.5e-55 186.5 0.0 5.3e-55 185.9 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 KUM65204.1 - 7.7e-18 65.1 0.4 5.9e-17 62.2 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 KUM65204.1 - 5.5e-08 33.0 0.0 2.2e-07 31.1 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KUM65204.1 - 4.8e-07 29.5 0.1 1.8e-06 27.7 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KUM65204.1 - 1.9e-05 24.8 0.0 3.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KUM65204.1 - 3.2e-05 23.7 0.0 0.0001 22.0 0.0 1.7 1 1 0 1 1 1 1 Archaeal ATPase KAP_NTPase PF07693.9 KUM65204.1 - 3.8e-05 22.8 0.0 5.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain DUF815 PF05673.8 KUM65204.1 - 0.00024 20.1 0.0 0.00039 19.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) G-alpha PF00503.15 KUM65204.1 - 0.0038 15.9 0.0 0.012 14.3 0.0 2.0 1 1 0 1 1 1 1 G-protein alpha subunit ATP-synt_ab PF00006.20 KUM65204.1 - 0.005 16.3 0.0 0.0078 15.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain PIF1 PF05970.9 KUM65204.1 - 0.026 13.4 0.0 0.045 12.7 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase ABC_tran PF00005.22 KUM65204.1 - 0.037 14.3 0.0 0.072 13.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 KUM65204.1 - 0.038 13.8 0.0 0.11 12.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KUM65204.1 - 0.042 13.3 0.0 0.099 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2075 PF09848.4 KUM65204.1 - 0.15 10.9 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 KUM65204.1 - 0.17 10.7 0.0 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.21 KUM65204.1 - 0.21 11.0 0.0 0.44 9.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Sld5 PF05916.6 KUM65206.1 - 8.9e-30 103.1 0.0 1.3e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein adh_short PF00106.20 KUM65208.1 - 5.1e-12 46.0 0.0 9.6e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM65208.1 - 1.2e-09 38.3 0.0 2.2e-09 37.4 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM65208.1 - 0.029 14.0 0.3 0.1 12.2 0.0 2.0 2 1 0 2 2 2 0 KR domain DUF3712 PF12505.3 KUM65209.1 - 6.6e-33 113.4 0.3 1.7e-32 112.0 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) ESSS PF10183.4 KUM65209.1 - 0.0075 16.6 0.1 0.014 15.7 0.1 1.4 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF1279 PF06916.8 KUM65209.1 - 0.033 14.4 0.0 0.075 13.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) WD40 PF00400.27 KUM65210.1 - 9.3e-71 231.3 25.7 2e-08 33.8 0.0 11.8 11 1 0 11 11 11 10 WD domain, G-beta repeat Utp12 PF04003.7 KUM65210.1 - 4.3e-21 74.8 0.4 7.1e-21 74.1 0.3 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 KUM65210.1 - 3.5e-07 28.7 2.3 0.013 13.7 0.0 5.1 5 1 1 6 6 6 3 Nucleoporin Nup120/160 DUF3312 PF11768.3 KUM65210.1 - 0.0066 14.7 0.0 0.11 10.7 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3312) Nucleoporin_N PF08801.6 KUM65210.1 - 0.01 14.6 1.9 7.1 5.2 0.0 4.0 2 1 2 5 5 5 0 Nup133 N terminal like Utp13 PF08625.6 KUM65210.1 - 0.058 13.0 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain P34-Arc PF04045.9 KUM65211.1 - 1.2e-87 293.1 0.0 1.6e-87 292.8 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Sel1 PF08238.7 KUM65214.1 - 1.8e-14 53.8 6.8 0.0005 20.6 1.2 4.3 4 0 0 4 4 4 3 Sel1 repeat Far-17a_AIG1 PF04750.9 KUM65215.1 - 4.5e-07 29.2 20.5 6.5e-07 28.7 14.2 1.2 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF1776 PF08643.5 KUM65216.1 - 1.8e-102 342.5 0.0 2.2e-102 342.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) WLM PF08325.5 KUM65217.1 - 2.3e-57 193.8 0.2 3.6e-57 193.2 0.1 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 KUM65217.1 - 0.00098 18.1 3.5 0.00098 18.1 2.5 3.3 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others SprT-like PF10263.4 KUM65217.1 - 0.005 16.5 0.3 0.023 14.3 0.0 2.2 2 0 0 2 2 2 1 SprT-like family DUF45 PF01863.12 KUM65217.1 - 0.025 14.3 1.3 0.067 12.9 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF45 DZR PF12773.2 KUM65217.1 - 2.8 7.8 14.2 51 3.7 9.9 2.3 1 1 0 1 1 1 0 Double zinc ribbon NOT2_3_5 PF04153.13 KUM65218.1 - 3.3e-33 114.3 1.4 5.2e-33 113.7 0.0 2.0 3 0 0 3 3 3 1 NOT2 / NOT3 / NOT5 family MRP-L47 PF06984.8 KUM65219.1 - 1.4e-20 72.9 0.0 2e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Clc-like PF07062.7 KUM65219.1 - 0.024 13.8 0.8 0.038 13.2 0.6 1.3 1 0 0 1 1 1 0 Clc-like WD40 PF00400.27 KUM65220.1 - 1.3e-28 97.7 6.1 3.8e-08 32.8 0.5 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 KUM65220.1 - 2.2e-06 26.0 0.9 0.0021 16.2 0.1 2.4 2 1 0 2 2 2 2 Nucleoporin Nup120/160 DIE2_ALG10 PF04922.7 KUM65221.1 - 1.1e-71 241.8 23.2 8.3e-65 219.2 10.6 3.0 2 1 0 2 2 2 2 DIE2/ALG10 family Beta-lactamase PF00144.19 KUM65222.1 - 6.7e-41 140.3 0.2 8.7e-41 140.0 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase VIT_2 PF13757.1 KUM65222.1 - 0.075 12.4 0.2 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain Fcf1 PF04900.7 KUM65223.1 - 3.3e-12 46.3 0.2 5e-05 23.3 0.0 2.9 2 1 0 2 2 2 2 Fcf1 PP2C PF00481.16 KUM65224.1 - 0.0013 18.2 0.1 0.12 11.7 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 KUM65224.1 - 0.0028 17.3 0.0 0.013 15.2 0.0 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KUM65224.1 - 0.0055 16.1 0.0 0.0087 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Imm40 PF15582.1 KUM65224.1 - 0.16 10.6 0.0 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 Immunity protein 40 Cmc1 PF08583.5 KUM65225.1 - 7.6e-17 60.8 3.1 1e-16 60.4 2.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CUE PF02845.11 KUM65226.1 - 8.9e-11 41.0 0.0 1.6e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 CUE domain FAD_binding_3 PF01494.14 KUM65227.1 - 1.9e-14 53.5 1.1 5e-13 48.8 0.1 2.3 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.19 KUM65227.1 - 0.00045 19.2 0.9 0.35 9.7 0.0 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KUM65227.1 - 0.0028 16.8 0.4 0.0053 15.8 0.0 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KUM65227.1 - 0.0037 17.2 0.4 0.0088 16.0 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KUM65227.1 - 0.0053 16.8 0.1 0.028 14.4 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 KUM65227.1 - 0.0098 14.7 0.0 0.049 12.4 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_9 PF13454.1 KUM65227.1 - 0.041 13.6 1.3 11 5.7 0.0 2.9 2 1 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KUM65227.1 - 0.043 13.6 0.1 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KUM65227.1 - 0.16 10.5 2.4 0.63 8.6 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.7 KUM65227.1 - 0.22 10.3 1.3 5 5.9 0.0 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein Syntaxin-6_N PF09177.6 KUM65228.1 - 0.023 15.1 0.4 10 6.6 0.0 3.2 3 0 0 3 3 3 0 Syntaxin 6, N-terminal APP_amyloid PF10515.4 KUM65228.1 - 0.15 12.3 0.0 0.55 10.5 0.0 2.0 1 0 0 1 1 1 0 beta-amyloid precursor protein C-terminus AAA_11 PF13086.1 KUM65229.1 - 3.1e-64 216.7 0.1 4.9e-64 216.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 KUM65229.1 - 1.7e-47 161.3 0.0 2.9e-47 160.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KUM65229.1 - 2.9e-14 52.5 0.1 4.6e-13 48.7 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KUM65229.1 - 1.7e-12 47.3 0.0 5.5e-08 32.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 KUM65229.1 - 8.7e-07 28.2 0.2 4.5e-05 22.5 0.2 2.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 KUM65229.1 - 4.8e-06 26.7 0.1 0.00019 21.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KUM65229.1 - 1.2e-05 25.0 0.0 0.022 14.2 0.0 2.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 KUM65229.1 - 1.2e-05 25.2 0.0 6.4e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KUM65229.1 - 7.6e-05 22.2 0.0 0.0012 18.3 0.0 2.3 1 1 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.11 KUM65229.1 - 0.00012 21.3 0.0 0.052 12.7 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein Helicase_RecD PF05127.9 KUM65229.1 - 0.00014 21.5 0.0 0.077 12.6 0.0 2.3 2 0 0 2 2 2 2 Helicase UvrD-helicase PF00580.16 KUM65229.1 - 0.00057 19.2 0.0 0.0014 17.9 0.0 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Flavi_DEAD PF07652.9 KUM65229.1 - 0.0014 18.4 0.1 0.0063 16.2 0.0 2.0 2 0 0 2 2 2 1 Flavivirus DEAD domain T2SE PF00437.15 KUM65229.1 - 0.0017 17.3 0.0 0.0029 16.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein PIF1 PF05970.9 KUM65229.1 - 0.0025 16.8 0.0 2 7.2 0.0 2.3 2 0 0 2 2 2 2 PIF1-like helicase AAA_16 PF13191.1 KUM65229.1 - 0.0045 16.9 0.0 0.011 15.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 KUM65229.1 - 0.0077 15.6 0.0 0.024 14.0 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein TrwB_AAD_bind PF10412.4 KUM65229.1 - 0.014 14.0 0.0 0.025 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain CbiA PF01656.18 KUM65229.1 - 0.015 14.7 0.2 0.052 12.9 0.2 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_5 PF07728.9 KUM65229.1 - 0.016 14.9 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zot PF05707.7 KUM65229.1 - 0.022 14.2 0.0 0.054 12.9 0.0 1.7 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_10 PF12846.2 KUM65229.1 - 0.027 13.9 0.0 0.21 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_25 PF13481.1 KUM65229.1 - 0.029 13.7 0.0 0.099 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KUM65229.1 - 0.035 14.2 0.0 0.2 11.8 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 KUM65229.1 - 0.11 11.9 0.0 2.9 7.2 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TK PF00265.13 KUM65229.1 - 0.16 11.5 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 Thymidine kinase Herpes_ori_bp PF02399.10 KUM65229.1 - 0.28 9.0 0.0 0.46 8.3 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein ERG4_ERG24 PF01222.12 KUM65230.1 - 2.1e-142 474.6 6.5 2.4e-142 474.5 4.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KUM65230.1 - 1.6e-05 24.3 0.1 5e-05 22.7 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Acetyltransf_1 PF00583.19 KUM65231.1 - 1.9e-05 24.5 0.0 3.9e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KUM65231.1 - 0.018 15.1 0.0 0.028 14.5 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KUM65231.1 - 0.064 13.3 0.1 0.27 11.3 0.1 2.0 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Cupin_2 PF07883.6 KUM65232.1 - 3e-11 42.6 0.0 8.4e-05 21.9 0.0 2.5 3 0 0 3 3 3 2 Cupin domain Cupin_6 PF12852.2 KUM65232.1 - 0.02 14.4 0.0 4.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Cupin Peptidase_S10 PF00450.17 KUM65234.1 - 3.9e-101 339.2 0.6 4.9e-101 338.8 0.4 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase HhH-GPD PF00730.20 KUM65235.1 - 9.8e-19 67.6 0.0 1.9e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KUM65235.1 - 9e-08 31.4 0.0 1.9e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif UQ_con PF00179.21 KUM65236.1 - 1.5e-36 124.8 0.0 1.7e-36 124.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KUM65236.1 - 0.00072 19.4 0.0 0.0009 19.1 0.0 1.3 1 1 0 1 1 1 1 RWD domain Nuc_recep-AF1 PF11825.3 KUM65236.1 - 0.059 13.2 0.1 0.11 12.4 0.0 1.5 2 0 0 2 2 2 0 Nuclear/hormone receptor activator site AF-1 UBX PF00789.15 KUM65237.1 - 4.4e-11 42.6 0.0 1.2e-10 41.2 0.0 1.7 2 0 0 2 2 2 1 UBX domain UBA_4 PF14555.1 KUM65237.1 - 1.4e-10 40.5 0.0 3e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Paf1 PF03985.8 KUM65237.1 - 0.34 9.5 6.4 0.53 8.9 4.5 1.2 1 0 0 1 1 1 0 Paf1 Pro_isomerase PF00160.16 KUM65238.1 - 2.8e-43 147.7 1.0 3.2e-43 147.6 0.7 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Occludin_ELL PF07303.8 KUM65240.1 - 1.7 9.4 32.8 0.24 12.1 5.1 4.9 3 1 3 6 6 6 0 Occludin homology domain Cep57_MT_bd PF06657.8 KUM65240.1 - 4.7 7.2 13.5 1.5 8.7 0.1 4.7 1 1 2 4 4 4 0 Centrosome microtubule-binding domain of Cep57 Baculo_p24 PF05073.7 KUM65240.1 - 7.4 6.0 18.2 0.082 12.4 0.8 3.1 3 0 0 3 3 3 0 Baculovirus P24 capsid protein RNA_pol_Rpb5_C PF01191.14 KUM65241.1 - 1.5e-35 120.5 0.1 2.4e-35 119.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 KUM65241.1 - 2e-28 98.6 0.0 3e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 KUM65241.1 - 0.021 14.6 0.0 0.05 13.3 0.0 1.6 2 0 0 2 2 2 0 Restriction endonuclease BetaGal_dom2 PF10435.4 KUM65242.1 - 4e-68 228.3 4.3 4e-68 228.3 2.9 1.7 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 KUM65242.1 - 4.1e-50 168.6 13.1 7e-27 93.8 1.8 3.1 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain Glyco_hydro_35 PF01301.14 KUM65242.1 - 7.9e-40 137.1 0.0 1.2e-39 136.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom3 PF13363.1 KUM65242.1 - 8.1e-28 95.6 0.2 1.6e-27 94.6 0.2 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 CARDB PF07705.6 KUM65242.1 - 0.14 12.2 1.5 25 4.9 0.0 3.6 3 0 0 3 3 3 0 CARDB Nol1_Nop2_Fmu PF01189.12 KUM65244.1 - 6.4e-31 107.7 0.0 1.8e-22 80.0 0.0 4.3 1 1 1 3 3 3 3 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 KUM65244.1 - 0.0094 15.9 0.0 0.041 13.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Glyco_hydro_35 PF01301.14 KUM65245.1 - 2e-48 165.3 0.0 2.6e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Cellulase PF00150.13 KUM65245.1 - 0.057 12.6 0.0 0.063 12.4 0.0 1.1 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Peptidase_M16 PF00675.15 KUM65246.1 - 7.9e-57 191.1 0.2 2e-56 189.8 0.2 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KUM65246.1 - 1.1e-41 142.5 0.0 1.9e-39 135.2 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain Epimerase PF01370.16 KUM65249.1 - 1.3e-21 77.1 0.0 1.8e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KUM65249.1 - 5.1e-12 45.0 0.0 6.4e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KUM65249.1 - 1.6e-07 31.5 0.0 2.4e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KUM65249.1 - 1.2e-06 28.5 0.0 2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KUM65249.1 - 3.9e-06 25.9 0.0 7.3e-05 21.8 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 KUM65249.1 - 9.5e-06 24.7 0.0 1.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 KUM65249.1 - 0.0014 18.3 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KUM65249.1 - 0.0022 16.9 0.0 0.0055 15.6 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Ldh_1_N PF00056.18 KUM65249.1 - 0.003 17.3 0.0 0.01 15.6 0.0 1.9 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KUM65249.1 - 0.0053 15.7 0.0 0.0073 15.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KUM65249.1 - 0.0067 16.7 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Ribosomal_L22 PF00237.14 KUM65251.1 - 2e-34 117.6 0.0 5.8e-34 116.1 0.0 1.7 1 1 1 2 2 2 1 Ribosomal protein L22p/L17e 2-Hacid_dh_C PF02826.14 KUM65252.1 - 4.6e-52 175.7 0.0 6.5e-52 175.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KUM65252.1 - 7.7e-20 70.7 0.0 9.5e-20 70.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KUM65252.1 - 0.0022 17.8 0.7 0.0041 16.9 0.1 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_N PF08240.7 KUM65253.1 - 1.6e-29 101.8 1.0 4.5e-29 100.3 0.5 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM65253.1 - 6.5e-15 54.8 0.2 1.3e-14 53.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Saccharop_dh PF03435.13 KUM65253.1 - 0.0019 17.2 0.2 0.0027 16.7 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase ApbA PF02558.11 KUM65253.1 - 0.029 13.8 0.0 0.054 12.9 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.20 KUM65254.1 - 2.1e-27 96.0 0.1 2.9e-27 95.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM65254.1 - 6e-19 68.7 0.0 7.3e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM65254.1 - 5.2e-12 45.7 0.1 7.5e-12 45.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM65254.1 - 1.3e-07 31.3 0.1 2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KUM65254.1 - 0.00046 19.1 0.0 0.00056 18.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KUM65254.1 - 0.0061 16.5 0.9 0.11 12.5 0.6 2.6 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KUM65254.1 - 0.029 13.3 0.0 0.039 12.9 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase Eno-Rase_NADH_b PF12242.3 KUM65254.1 - 0.031 14.0 0.2 0.072 12.8 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ACT_7 PF13840.1 KUM65254.1 - 0.06 12.8 0.3 0.34 10.4 0.0 2.2 2 0 0 2 2 2 0 ACT domain Ldh_1_N PF00056.18 KUM65254.1 - 0.1 12.4 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Bcl-2 PF00452.14 KUM65254.1 - 0.13 12.4 0.0 0.37 10.9 0.0 1.8 2 0 0 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family Gtr1_RagA PF04670.7 KUM65254.1 - 0.15 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Fungal_trans PF04082.13 KUM65255.1 - 1.1e-13 50.6 0.0 4.8e-13 48.5 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM65255.1 - 8.3e-06 25.6 10.4 1.5e-05 24.8 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KUM65256.1 - 2.4e-17 63.3 0.1 2.8e-17 63.1 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM65256.1 - 7.5e-09 35.4 0.0 9.1e-09 35.2 0.0 1.0 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM65256.1 - 0.00016 21.2 0.0 0.00017 21.0 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KUM65256.1 - 0.00016 21.4 0.0 0.0002 21.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KUM65256.1 - 0.00036 20.5 0.1 0.016 15.1 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 KUM65256.1 - 0.0016 17.5 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 KUM65256.1 - 0.0026 17.5 0.4 0.0042 16.8 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 KUM65256.1 - 0.029 13.2 0.0 0.071 11.9 0.0 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain ApbA PF02558.11 KUM65256.1 - 0.079 12.3 0.0 0.094 12.1 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CW_binding_2 PF04122.7 KUM65256.1 - 0.11 12.7 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 2-Hacid_dh_C PF02826.14 KUM65256.1 - 0.13 11.3 0.1 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short_C2 PF13561.1 KUM65257.1 - 5.2e-09 36.2 0.1 5.7e-09 36.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KUM65257.1 - 0.00021 21.2 0.1 0.00044 20.1 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase Ferric_reduct PF01794.14 KUM65258.1 - 1.5e-20 73.5 7.7 4.4e-20 72.0 5.3 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KUM65258.1 - 8.2e-13 48.1 0.2 1.2e-06 28.3 0.1 2.5 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.7 KUM65258.1 - 2e-12 47.2 0.0 1e-07 31.9 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain ABC2_membrane PF01061.19 KUM65259.1 - 5.6e-92 306.6 50.5 5.7e-50 169.3 14.8 3.3 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 KUM65259.1 - 2.2e-39 134.8 0.4 1.7e-18 67.1 0.0 3.6 4 0 0 4 4 4 2 ABC transporter PDR_CDR PF06422.7 KUM65259.1 - 4.9e-39 132.1 2.0 8.9e-36 121.6 0.1 3.3 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KUM65259.1 - 1.7e-22 79.2 0.2 4.1e-22 78.0 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 KUM65259.1 - 2.7e-07 29.9 0.2 6.5e-05 22.1 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KUM65259.1 - 5.5e-07 29.1 0.1 0.0005 19.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KUM65259.1 - 5.7e-05 23.1 0.6 0.0093 15.9 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.2 KUM65259.1 - 0.00024 20.2 16.1 0.00024 20.2 11.2 3.3 2 1 1 3 3 2 1 ABC-2 family transporter protein AAA_29 PF13555.1 KUM65259.1 - 0.00037 19.9 2.1 0.019 14.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 KUM65259.1 - 0.00051 19.9 1.5 0.018 14.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain cobW PF02492.14 KUM65259.1 - 0.00094 18.6 0.3 0.047 13.1 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 KUM65259.1 - 0.0035 17.4 0.2 1.1 9.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KUM65259.1 - 0.0036 17.5 0.0 0.33 11.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KUM65259.1 - 0.0043 16.3 0.0 0.39 9.9 0.0 3.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_19 PF13245.1 KUM65259.1 - 0.012 15.3 0.5 6.4 6.6 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain AAA_21 PF13304.1 KUM65259.1 - 0.013 15.4 0.0 2.3 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KUM65259.1 - 0.016 15.9 0.0 0.35 11.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KUM65259.1 - 0.038 14.2 0.0 11 6.1 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KUM65259.1 - 0.072 13.2 0.0 23 5.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.7 KUM65259.1 - 0.078 12.6 4.4 3.1 7.4 0.1 3.2 3 0 0 3 3 3 0 NACHT domain Miro PF08477.8 KUM65259.1 - 0.082 13.4 0.0 16 6.0 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein IstB_IS21 PF01695.12 KUM65259.1 - 0.086 12.2 0.2 2 7.7 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_10 PF12846.2 KUM65259.1 - 0.1 11.9 2.5 17 4.7 0.1 3.4 3 0 0 3 3 3 0 AAA-like domain AAA_30 PF13604.1 KUM65259.1 - 0.17 11.4 0.5 8.2 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain Chitin_bind_3 PF03067.10 KUM65260.1 - 1.1e-17 64.8 0.9 1.6e-17 64.3 0.6 1.2 1 0 0 1 1 1 1 Chitin binding domain APH PF01636.18 KUM65261.1 - 1.1e-13 51.4 0.0 2.4e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KUM65261.1 - 1.7e-05 24.4 0.0 3.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KUM65261.1 - 5e-05 22.5 0.0 0.00025 20.2 0.0 2.1 3 0 0 3 3 3 1 Protein kinase domain CRAL_TRIO PF00650.15 KUM65261.1 - 0.012 15.0 0.0 0.026 14.0 0.0 1.6 1 1 0 1 1 1 0 CRAL/TRIO domain Fructosamin_kin PF03881.9 KUM65261.1 - 0.092 11.6 0.0 2.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Fructosamine kinase Arylsulfotran_2 PF14269.1 KUM65262.1 - 5.6e-60 203.0 6.6 8.2e-60 202.4 4.6 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KUM65262.1 - 5.1e-21 74.7 5.7 2.1e-19 69.4 3.9 2.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) CybS PF05328.7 KUM65262.1 - 0.059 13.0 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 CybS HAD_2 PF13419.1 KUM65264.1 - 5.9e-32 111.2 0.0 7.2e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase SAP30_Sin3_bdg PF13867.1 KUM65264.1 - 0.036 13.9 0.0 0.066 13.0 0.0 1.5 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Hydrolase PF00702.21 KUM65264.1 - 0.052 13.9 0.0 0.33 11.3 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase GAT PF03127.9 KUM65265.1 - 1.7e-13 50.3 0.0 6e-13 48.6 0.0 1.8 2 0 0 2 2 2 1 GAT domain VHS PF00790.14 KUM65265.1 - 2.2e-05 24.1 0.0 0.00012 21.6 0.0 2.2 3 0 0 3 3 3 1 VHS domain ADH_zinc_N_2 PF13602.1 KUM65267.1 - 7.1e-22 78.6 0.0 1.3e-21 77.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KUM65267.1 - 2.7e-16 59.2 0.1 4.2e-16 58.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KUM65267.1 - 0.00027 21.0 1.4 0.00042 20.3 1.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DFP PF04127.10 KUM65267.1 - 0.054 13.1 0.1 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Methyltransf_11 PF08241.7 KUM65268.1 - 2.4e-12 47.1 0.0 4.3e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM65268.1 - 9.5e-12 44.7 0.0 1.4e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM65268.1 - 4.9e-10 39.3 0.0 7e-10 38.8 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM65268.1 - 5.6e-10 39.7 0.0 1.1e-09 38.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM65268.1 - 2.2e-09 37.6 0.0 4.4e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM65268.1 - 4.6e-08 33.3 0.0 1.2e-07 32.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KUM65268.1 - 4.8e-06 26.0 0.0 7.3e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KUM65268.1 - 0.00034 20.6 0.0 0.00044 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KUM65268.1 - 0.015 14.5 0.0 0.026 13.7 0.0 1.4 1 1 0 1 1 1 0 O-methyltransferase FmrO PF07091.6 KUM65268.1 - 0.016 14.1 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) CheR PF01739.13 KUM65268.1 - 0.029 13.6 0.0 0.44 9.7 0.0 2.0 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.12 KUM65268.1 - 0.041 12.9 0.0 0.057 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_32 PF13679.1 KUM65268.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 KUM65268.1 - 0.15 11.1 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MFS_1 PF07690.11 KUM65270.1 - 5.2e-31 107.6 42.2 1.9e-20 72.8 10.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily bZIP_1 PF00170.16 KUM65271.1 - 5.1e-07 29.5 1.9 9.7e-07 28.6 1.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor Glutaredoxin2_C PF04399.8 KUM65271.1 - 0.094 12.2 0.1 0.61 9.6 0.0 2.0 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain TMEMspv1-c74-12 PF11044.3 KUM65272.1 - 2.5 7.6 4.1 7.2 6.2 2.9 1.8 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein ABC_tran PF00005.22 KUM65273.1 - 3.9e-17 62.8 0.0 6.7e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 KUM65273.1 - 0.0012 18.0 0.0 0.0022 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KUM65273.1 - 0.018 15.0 0.0 0.03 14.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Arch_ATPase PF01637.13 KUM65273.1 - 0.027 14.1 0.0 0.055 13.1 0.0 1.6 2 0 0 2 2 2 0 Archaeal ATPase Rad17 PF03215.10 KUM65273.1 - 0.04 12.5 0.0 0.059 12.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA PF00004.24 KUM65273.1 - 0.062 13.4 0.0 0.19 11.9 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ribosomal_S28e PF01200.13 KUM65273.1 - 0.07 12.8 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S28e AAA_22 PF13401.1 KUM65273.1 - 0.087 12.9 0.0 0.17 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 KUM65273.1 - 0.097 12.1 0.0 0.25 10.8 0.0 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.1 KUM65273.1 - 0.13 13.0 0.0 0.26 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC2_membrane PF01061.19 KUM65274.1 - 3.5e-09 36.1 12.2 5.7e-08 32.1 8.5 2.0 1 1 0 1 1 1 1 ABC-2 type transporter ER_lumen_recept PF00810.13 KUM65274.1 - 0.021 15.2 0.4 0.035 14.6 0.1 1.4 1 1 0 1 1 1 0 ER lumen protein retaining receptor FA_desaturase PF00487.19 KUM65274.1 - 0.19 11.1 2.9 0.27 10.6 2.0 1.3 1 1 0 1 1 1 0 Fatty acid desaturase SPC12 PF06645.8 KUM65274.1 - 1.4 8.7 5.7 1.3 8.8 2.2 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Mmp37 PF09139.6 KUM65276.1 - 4e-138 459.9 0.0 4.9e-138 459.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 Aminotran_1_2 PF00155.16 KUM65277.1 - 7.5e-62 209.3 0.0 9e-62 209.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.8 KUM65277.1 - 0.066 11.8 0.0 0.099 11.2 0.0 1.2 1 0 0 1 1 1 0 Allinase Cys_Met_Meta_PP PF01053.15 KUM65277.1 - 0.074 11.3 0.0 0.14 10.4 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF1115 PF06544.7 KUM65278.1 - 1.6e-19 69.8 0.0 3.1e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) CASP_C PF08172.7 KUM65280.1 - 7.4e-89 297.0 4.3 7.4e-89 297.0 3.0 3.3 2 1 2 4 4 4 1 CASP C terminal Vps39_2 PF10367.4 KUM65281.1 - 2e-06 27.9 0.0 5.6e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 KUM65281.1 - 0.028 14.4 0.0 0.089 12.8 0.0 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Fibrillarin PF01269.12 KUM65282.1 - 3.9e-106 353.1 0.0 4.7e-106 352.8 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 KUM65282.1 - 3.4e-06 26.7 0.0 5.6e-06 26.0 0.0 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 KUM65282.1 - 0.011 15.2 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF3455 PF11937.3 KUM65283.1 - 2.3e-47 161.2 0.1 2.9e-47 160.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.3 KUM65283.1 - 1.8e-23 82.1 0.4 4.2e-23 80.9 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2990) Peptidase_S8 PF00082.17 KUM65283.1 - 0.028 13.5 0.2 0.036 13.1 0.2 1.2 1 0 0 1 1 1 0 Subtilase family Dioxygenase_C PF00775.16 KUM65284.1 - 5e-48 162.7 0.0 7.3e-48 162.2 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KUM65284.1 - 2.8e-19 68.8 0.1 7.1e-19 67.5 0.0 1.7 2 0 0 2 2 2 1 Catechol dioxygenase N terminus Fasciclin PF02469.17 KUM65285.1 - 5e-43 146.1 0.0 7.2e-25 87.4 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain LSM PF01423.17 KUM65286.1 - 3.2e-21 74.6 0.6 4.2e-21 74.2 0.4 1.2 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.1 KUM65286.1 - 0.0039 17.6 4.6 0.0064 16.9 3.2 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Zn_clus PF00172.13 KUM65287.1 - 0.051 13.5 9.9 0.12 12.2 6.8 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 KUM65288.1 - 9.4e-07 28.2 0.0 1.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM65288.1 - 0.017 14.2 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Cation_efflux PF01545.16 KUM65289.1 - 1.2e-27 96.7 6.0 1.4e-27 96.4 4.1 1.1 1 0 0 1 1 1 1 Cation efflux family DUF4578 PF15147.1 KUM65289.1 - 0.11 12.9 0.1 0.24 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) DctQ PF04290.7 KUM65289.1 - 0.67 9.7 5.7 1.7 8.4 0.2 2.3 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component zf-C2H2_jaz PF12171.3 KUM65290.1 - 3.2e-07 30.2 0.6 5.5e-07 29.5 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KUM65290.1 - 4.6e-05 23.4 0.9 7.6e-05 22.7 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KUM65290.1 - 0.024 14.9 0.7 0.042 14.1 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 KUM65290.1 - 0.085 12.9 0.6 0.36 10.9 0.1 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DDHD PF02862.12 KUM65290.1 - 1.4 8.6 6.9 7.8 6.2 0.1 2.1 2 0 0 2 2 2 0 DDHD domain DUF3340 PF11818.3 KUM65290.1 - 4.9 7.0 17.4 1.5 8.7 7.5 2.1 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) BIR PF00653.16 KUM65291.1 - 7.7e-43 144.7 5.0 8.1e-22 77.4 0.1 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain AMP-binding PF00501.23 KUM65292.1 - 1.2e-41 142.5 0.0 1.8e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 KUM65292.1 - 2.4e-11 43.7 0.1 5.4e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KUM65292.1 - 1.7e-06 28.8 0.0 5.7e-06 27.1 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Condensation PF00668.15 KUM65292.1 - 3.7e-06 25.9 0.0 5.7e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Condensation domain Copine PF07002.11 KUM65292.1 - 0.07 12.8 0.1 5.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Copine Pyridox_oxidase PF01243.15 KUM65293.1 - 2.9e-07 30.3 0.0 5.2e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Methyltransf_2 PF00891.13 KUM65294.1 - 5.4e-21 74.8 0.0 7.5e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase MarR_2 PF12802.2 KUM65294.1 - 4.2e-05 23.1 0.0 8.5e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.15 KUM65294.1 - 0.0055 16.7 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulator HTH_AraC PF00165.18 KUM65294.1 - 0.095 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family MarR PF01047.17 KUM65294.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_Crp_2 PF13545.1 KUM65294.1 - 0.17 11.7 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain AMP-binding PF00501.23 KUM65295.1 - 2.5e-21 75.5 0.0 2.9e-21 75.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme GvpK PF05121.7 KUM65296.1 - 0.07 12.9 0.0 0.095 12.5 0.0 1.2 1 0 0 1 1 1 0 Gas vesicle protein K TFIID-18kDa PF02269.11 KUM65297.1 - 1.3e-28 98.5 0.2 1.2e-27 95.5 0.1 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit MFS_1 PF07690.11 KUM65298.1 - 1.6e-14 53.4 13.3 1.6e-14 53.4 9.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TP_methylase PF00590.15 KUM65299.1 - 1.2e-20 74.1 0.2 1.9e-20 73.5 0.2 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases I_LWEQ PF01608.12 KUM65299.1 - 0.097 12.6 0.2 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 I/LWEQ domain Cyclase PF04199.8 KUM65300.1 - 1.4e-15 57.3 0.0 2.2e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Sigma70_r1_2 PF00140.15 KUM65300.1 - 0.087 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 adh_short_C2 PF13561.1 KUM65301.1 - 6.3e-28 98.1 0.1 7.2e-28 97.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KUM65301.1 - 9.8e-28 97.1 0.7 1.3e-27 96.7 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM65301.1 - 2.6e-12 46.7 0.3 4e-12 46.1 0.2 1.2 1 0 0 1 1 1 1 KR domain Chorion_S16 PF05836.7 KUM65301.1 - 0.051 13.4 0.6 0.14 12.0 0.2 1.8 1 1 0 1 1 1 0 Chorion protein S16 adh_short_C2 PF13561.1 KUM65302.1 - 1.9e-27 96.6 0.0 2.6e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KUM65302.1 - 4.2e-25 88.6 0.0 5.6e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM65302.1 - 4.2e-14 52.6 0.0 5.6e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM65302.1 - 0.0002 20.8 0.0 0.00034 20.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KUM65302.1 - 0.03 13.0 0.0 0.043 12.5 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Pectate_lyase_3 PF12708.2 KUM65303.1 - 1.5e-81 273.7 26.9 7e-62 209.4 9.2 2.9 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KUM65303.1 - 6.1e-09 35.2 2.8 0.00025 20.4 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Abhydrolase_2 PF02230.11 KUM65304.1 - 2.2e-05 24.0 0.0 3.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KUM65304.1 - 0.00052 19.8 0.0 0.00075 19.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KUM65304.1 - 0.0016 17.9 0.1 0.0032 16.9 0.1 1.6 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.4 KUM65304.1 - 0.0019 17.5 0.7 0.0052 16.0 0.0 1.8 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KUM65304.1 - 0.012 14.8 0.0 0.15 11.3 0.1 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KUM65304.1 - 0.043 13.7 0.0 0.061 13.1 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family CRAL_TRIO PF00650.15 KUM65305.1 - 7.7e-44 148.9 0.0 1.4e-43 148.1 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KUM65305.1 - 6.6e-16 58.1 0.1 2e-15 56.6 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KUM65305.1 - 1.4e-09 38.0 0.0 2.4e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Skp1 PF01466.14 KUM65305.1 - 0.018 15.0 0.5 0.32 11.0 0.2 2.4 2 0 0 2 2 2 0 Skp1 family, dimerisation domain DUF2681 PF10883.3 KUM65305.1 - 0.051 13.7 0.4 0.11 12.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Pkinase PF00069.20 KUM65307.1 - 1.3e-75 253.9 0.0 1.5e-75 253.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM65307.1 - 3.9e-32 111.3 0.0 4.5e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM65307.1 - 0.0006 18.8 0.0 0.0017 17.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KUM65307.1 - 0.001 18.1 0.1 0.0015 17.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KUM65307.1 - 0.012 15.3 0.2 0.029 14.1 0.2 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KUM65307.1 - 0.07 11.9 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DASH_Dam1 PF08653.5 KUM65308.1 - 1.8e-29 101.2 1.6 2.5e-29 100.7 1.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 Ribosomal_60s PF00428.14 KUM65308.1 - 0.035 14.4 0.1 0.07 13.5 0.1 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein UCH PF00443.24 KUM65309.1 - 3e-51 174.1 2.0 3.9e-51 173.7 1.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KUM65309.1 - 2e-27 96.4 0.4 2.6e-27 96.0 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KUM65309.1 - 0.0027 17.7 1.8 0.0027 17.7 1.3 3.3 3 1 1 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein OrfB_Zn_ribbon PF07282.6 KUM65309.1 - 0.13 11.9 2.0 3.6 7.3 0.0 3.0 3 0 0 3 3 3 0 Putative transposase DNA-binding domain HIT PF01230.18 KUM65310.1 - 1.1e-20 73.9 0.2 1.5e-20 73.5 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KUM65310.1 - 4.5e-13 49.4 0.3 6.4e-13 48.9 0.0 1.4 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KUM65310.1 - 0.00015 21.4 0.0 0.0002 20.9 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Fringe PF02434.11 KUM65311.1 - 2.1e-06 27.1 2.9 1.9e-05 24.0 0.4 2.7 2 1 0 2 2 2 1 Fringe-like Galactosyl_T PF01762.16 KUM65311.1 - 0.041 13.4 0.0 0.11 12.1 0.0 1.6 1 1 0 1 1 1 0 Galactosyltransferase NAD_binding_10 PF13460.1 KUM65312.1 - 1.7e-19 70.5 0.0 2.5e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KUM65312.1 - 6.9e-18 64.7 0.0 8.4e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KUM65312.1 - 7.8e-15 54.9 0.1 1.8e-14 53.7 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KUM65312.1 - 2.8e-11 42.6 0.1 6.4e-11 41.4 0.1 1.6 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KUM65312.1 - 1.2e-09 37.4 0.0 1.6e-08 33.8 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KUM65312.1 - 3.4e-07 29.4 0.8 0.00075 18.4 0.5 3.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KUM65312.1 - 0.00033 20.6 0.0 0.0053 16.6 0.0 2.4 1 1 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 KUM65312.1 - 0.0011 18.0 0.0 0.002 17.2 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 KUM65312.1 - 0.016 14.8 0.0 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 KR domain DDE_Tnp_1_3 PF13612.1 KUM65312.1 - 0.031 14.0 0.0 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain HEM4 PF02602.10 KUM65313.1 - 6.4e-33 113.9 0.0 8.1e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Glyco_trans_2_3 PF13632.1 KUM65314.1 - 3.3e-11 43.2 2.1 7.7e-11 42.0 1.5 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KUM65314.1 - 8.4e-08 32.2 0.1 1.4e-06 28.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KUM65314.1 - 1.5e-05 24.3 0.1 7.9e-05 22.0 0.1 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.10 KUM65314.1 - 0.036 12.4 0.1 0.52 8.6 0.1 2.2 1 1 0 1 1 1 0 Chitin synthase ATP-synt_C PF00137.16 KUM65314.1 - 0.11 12.4 2.9 0.51 10.2 0.3 2.9 3 0 0 3 3 3 0 ATP synthase subunit C Ank_2 PF12796.2 KUM65315.1 - 1.2e-66 221.0 37.6 3.7e-17 62.4 2.9 5.7 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KUM65315.1 - 6.9e-47 154.9 28.8 5.6e-06 25.8 0.0 10.7 10 0 0 10 10 10 10 Ankyrin repeat Ank_4 PF13637.1 KUM65315.1 - 1.5e-39 133.6 10.0 4.2e-07 30.2 0.1 8.3 3 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM65315.1 - 5.5e-34 112.8 16.8 0.0014 18.6 0.0 10.4 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.1 KUM65315.1 - 1.2e-33 114.2 22.7 6.5e-08 32.5 0.1 9.1 3 2 7 10 10 10 10 Ankyrin repeats (many copies) NACHT PF05729.7 KUM65315.1 - 1.5e-10 41.0 0.0 8.4e-09 35.2 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KUM65315.1 - 4.6e-10 39.7 0.6 2.4e-09 37.4 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KUM65315.1 - 0.012 15.7 0.0 0.043 13.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KUM65315.1 - 0.053 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.1 KUM65315.1 - 0.064 13.5 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Glyco_hydro_15 PF00723.16 KUM65316.1 - 2e-107 359.5 0.2 2.2e-107 359.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Ank_2 PF12796.2 KUM65317.1 - 2e-104 342.1 22.2 4.1e-16 59.0 0.1 12.0 4 3 10 14 14 14 13 Ankyrin repeats (3 copies) Ank PF00023.25 KUM65317.1 - 1.8e-74 242.0 44.5 3.9e-09 35.8 0.2 22.8 25 1 0 25 25 25 14 Ankyrin repeat Ank_3 PF13606.1 KUM65317.1 - 3.3e-57 184.7 26.5 3.9e-06 26.5 0.0 21.8 22 0 0 22 22 22 10 Ankyrin repeat Ank_4 PF13637.1 KUM65317.1 - 5.5e-55 182.8 26.7 2e-07 31.3 0.1 16.0 9 5 7 17 17 17 12 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM65317.1 - 1e-53 178.1 24.8 2.5e-06 27.5 0.2 18.1 10 5 10 20 20 20 12 Ankyrin repeats (many copies) NACHT PF05729.7 KUM65317.1 - 1e-06 28.5 0.3 5.2e-06 26.2 0.0 2.3 3 0 0 3 3 3 1 NACHT domain AAA_16 PF13191.1 KUM65317.1 - 0.00012 22.0 0.8 0.0012 18.9 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KUM65317.1 - 0.011 15.8 0.1 0.051 13.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Ribonuclease_3 PF00636.21 KUM65318.1 - 1.3e-07 32.0 0.0 4.3e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KUM65318.1 - 4.5e-06 26.6 0.0 6e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like FMO-like PF00743.14 KUM65319.1 - 7.1e-30 103.7 0.0 8.7e-16 57.2 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KUM65319.1 - 2.1e-20 73.6 0.3 2.8e-19 69.9 0.2 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KUM65319.1 - 4.6e-10 38.9 0.3 6e-08 31.9 0.0 2.7 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KUM65319.1 - 5.2e-07 29.7 0.0 0.019 14.8 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM65319.1 - 1.2e-06 28.3 0.0 0.0018 18.0 0.0 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KUM65319.1 - 0.00014 21.8 0.2 0.00054 19.9 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 KUM65319.1 - 0.054 13.5 0.1 0.86 9.7 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 KUM65319.1 - 0.071 13.4 0.0 0.47 10.7 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Thi4 PF01946.12 KUM65319.1 - 0.13 11.3 0.9 0.18 10.8 0.1 1.5 2 0 0 2 2 2 0 Thi4 family MFS_1 PF07690.11 KUM65320.1 - 1.2e-26 93.2 24.1 1.5e-26 92.9 16.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Ribosomal_L31e PF01198.14 KUM65321.1 - 1.7e-36 123.7 1.7 3.1e-36 122.8 1.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L31e CN_hydrolase PF00795.17 KUM65321.1 - 3.9e-32 111.0 0.0 5.7e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MS_channel PF00924.13 KUM65321.1 - 0.086 12.1 0.1 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel DLH PF01738.13 KUM65322.1 - 1.2e-33 116.1 0.0 1.4e-33 116.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KUM65322.1 - 1.9e-05 24.4 0.0 2.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM65322.1 - 0.031 13.8 0.0 0.073 12.6 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Ytp1 PF10355.4 KUM65323.1 - 5.1e-110 366.9 8.9 6.7e-110 366.5 6.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KUM65323.1 - 5.8e-20 70.8 7.9 7.2e-18 64.0 0.9 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF2427) Zn_clus PF00172.13 KUM65324.1 - 0.00011 22.0 8.1 0.0002 21.1 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KaiA PF07688.7 KUM65324.1 - 0.012 14.8 0.2 0.022 14.0 0.1 1.4 1 0 0 1 1 1 0 KaiA domain Ran_BP1 PF00638.13 KUM65325.1 - 2.4e-09 37.3 0.0 4.8e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain PAP1 PF08601.5 KUM65326.1 - 1 8.9 15.2 1.3 8.6 10.5 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Macoilin PF09726.4 KUM65326.1 - 8.7 4.4 15.6 10 4.2 10.8 1.0 1 0 0 1 1 1 0 Transmembrane protein TFIIA PF03153.8 KUM65326.1 - 9.2 6.0 7.9 11 5.8 5.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Gaa1 PF04114.9 KUM65327.1 - 5.8e-104 348.5 3.0 8.5e-104 348.0 2.1 1.2 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Rhomboid PF01694.17 KUM65328.1 - 6.7e-15 55.3 9.7 6.7e-15 55.3 6.7 1.8 2 0 0 2 2 2 1 Rhomboid family 5TM-5TMR_LYT PF07694.7 KUM65328.1 - 0.0016 17.8 1.8 0.0029 16.9 0.9 1.6 1 1 0 1 1 1 1 5TMR of 5TMR-LYT PCI PF01399.22 KUM65329.1 - 2.6e-10 40.5 0.0 5.7e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 PCI domain Chitin_bind_1 PF00187.14 KUM65330.1 - 0.0023 17.8 7.4 0.0027 17.6 3.3 2.4 2 0 0 2 2 2 1 Chitin recognition protein LysM PF01476.15 KUM65330.1 - 0.038 13.8 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 LysM domain Macoilin PF09726.4 KUM65330.1 - 6.8 4.8 7.0 9.1 4.4 4.9 1.1 1 0 0 1 1 1 0 Transmembrane protein PEGSRP PF07623.6 KUM65331.1 - 0.14 11.4 1.1 0.3 10.4 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1584) UBA_4 PF14555.1 KUM65332.1 - 0.0005 19.5 0.0 0.00082 18.8 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain Rad10 PF03834.9 KUM65333.1 - 0.054 13.2 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Sec23_trunk PF04811.10 KUM65334.1 - 1.2e-72 244.1 0.0 2.4e-72 243.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KUM65334.1 - 3.2e-24 84.3 0.1 4.5e-23 80.6 0.0 2.7 3 0 0 3 3 3 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 KUM65334.1 - 7.1e-18 63.8 5.3 1.2e-17 63.1 3.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 KUM65334.1 - 3.6e-17 62.6 0.0 8.5e-17 61.4 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 KUM65334.1 - 3.2e-10 39.5 0.0 6.4e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat TEX12 PF15219.1 KUM65334.1 - 0.25 11.3 0.6 0.78 9.7 0.4 1.8 1 0 0 1 1 1 0 Testis-expressed 12 Kinesin PF00225.18 KUM65336.1 - 3.1e-81 272.6 0.9 3.1e-81 272.6 0.6 2.0 2 0 0 2 2 2 1 Kinesin motor domain HHH PF00633.18 KUM65336.1 - 1.4e-06 27.6 0.1 0.051 13.2 0.0 3.4 3 0 0 3 3 3 2 Helix-hairpin-helix motif HHH_5 PF14520.1 KUM65336.1 - 0.0048 17.0 0.0 0.025 14.7 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_3 PF12836.2 KUM65336.1 - 0.07 13.0 0.1 6.4 6.7 0.0 2.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif TPR_12 PF13424.1 KUM65336.1 - 0.12 12.3 1.3 3.4 7.6 0.8 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Syntaxin PF00804.20 KUM65336.1 - 0.44 10.7 5.3 0.45 10.7 1.2 2.7 2 0 0 2 2 2 0 Syntaxin adh_short PF00106.20 KUM65337.1 - 7e-16 58.5 0.0 9.9e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM65337.1 - 4.2e-05 23.4 0.0 6.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM65337.1 - 0.00016 21.3 0.0 0.00024 20.8 0.0 1.2 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.11 KUM65338.1 - 3.2e-36 124.7 70.4 4.5e-26 91.3 25.4 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM65338.1 - 3.8e-05 22.4 36.3 0.0039 15.8 10.3 3.2 2 2 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 KUM65338.1 - 0.014 15.1 6.0 0.04 13.7 0.3 2.9 2 0 0 2 2 2 0 MFS_1 like family Alkyl_sulf_C PF14864.1 KUM65338.1 - 0.095 12.6 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal AIM24 PF01987.12 KUM65339.1 - 1.7e-45 155.0 0.0 2.3e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 PQQ_2 PF13360.1 KUM65339.1 - 7.9e-05 22.2 0.3 0.00012 21.5 0.2 1.3 1 0 0 1 1 1 1 PQQ-like domain DUF4402 PF14352.1 KUM65339.1 - 0.0061 17.0 0.4 0.018 15.4 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4402) ABC_membrane PF00664.18 KUM65340.1 - 1.3e-35 123.1 13.9 1.7e-35 122.7 9.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KUM65340.1 - 9.6e-34 116.6 0.0 1.9e-33 115.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KUM65340.1 - 7e-07 29.4 0.1 0.0034 17.3 0.0 2.6 2 1 1 3 3 3 2 AAA domain SMC_N PF02463.14 KUM65340.1 - 2.3e-05 23.7 0.0 0.024 13.8 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KUM65340.1 - 6.8e-05 22.9 0.0 0.001 19.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KUM65340.1 - 0.0005 20.8 0.1 0.0012 19.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KUM65340.1 - 0.0017 18.5 0.0 0.0082 16.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KUM65340.1 - 0.0024 17.7 0.0 0.045 13.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KUM65340.1 - 0.0025 17.3 0.0 0.0062 16.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 KUM65340.1 - 0.0035 16.5 0.0 0.0067 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 KUM65340.1 - 0.0081 15.6 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.2 KUM65340.1 - 0.013 14.9 0.2 0.064 12.6 0.0 2.0 1 1 1 2 2 2 0 AAA-like domain AAA_23 PF13476.1 KUM65340.1 - 0.014 15.6 0.3 0.041 14.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.1 KUM65340.1 - 0.017 14.5 0.1 0.053 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KUM65340.1 - 0.033 14.5 0.0 0.098 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KUM65340.1 - 0.045 13.4 0.0 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 KUM65340.1 - 0.045 13.7 0.0 0.21 11.5 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA PF00004.24 KUM65340.1 - 0.056 13.6 0.0 0.31 11.2 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KUM65340.1 - 0.072 12.9 0.1 0.37 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 KUM65340.1 - 0.078 11.6 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein SbcCD_C PF13558.1 KUM65340.1 - 0.24 11.3 1.8 1.4 8.9 0.3 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Cyto_heme_lyase PF01265.12 KUM65341.1 - 2.2e-76 256.8 0.5 3.6e-75 252.8 0.3 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase GHMP_kinases_N PF00288.21 KUM65342.1 - 4.2e-11 42.7 0.4 9.1e-11 41.6 0.2 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain Ndc1_Nup PF09531.5 KUM65343.1 - 2.6e-156 521.5 0.2 2.9e-156 521.4 0.1 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.1 KUM65344.1 - 4.9e-25 87.5 8.3 5.4e-25 87.3 2.1 2.4 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 KUM65344.1 - 1.7e-16 59.6 2.7 1.7e-16 59.6 1.9 2.6 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 KUM65344.1 - 0.00011 22.3 2.5 0.00011 22.3 1.7 2.9 2 2 0 2 2 2 1 Syntaxin Synaptobrevin PF00957.16 KUM65344.1 - 0.0022 17.5 0.6 0.0091 15.5 0.4 2.1 1 0 0 1 1 1 1 Synaptobrevin MCPsignal PF00015.16 KUM65344.1 - 0.037 13.5 5.5 0.055 12.9 1.2 2.2 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF651 PF04895.7 KUM65344.1 - 0.076 12.6 0.5 0.34 10.5 0.1 2.2 2 0 0 2 2 2 0 Archaeal protein of unknown function (DUF651) DUF883 PF05957.8 KUM65344.1 - 0.1 12.9 0.1 0.1 12.9 0.1 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF1664 PF07889.7 KUM65344.1 - 0.15 11.8 2.8 3.1 7.5 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) T2SF PF00482.18 KUM65344.1 - 0.19 11.6 1.4 0.22 11.4 0.1 1.9 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F SlyX PF04102.7 KUM65344.1 - 0.26 11.6 0.3 0.26 11.6 0.2 3.7 2 1 2 4 4 4 0 SlyX OmpH PF03938.9 KUM65344.1 - 0.95 9.3 10.3 1.2 9.0 6.8 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) rRNA_proc-arch PF13234.1 KUM65345.1 - 8.7e-102 339.8 0.2 1.6e-101 339.0 0.2 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 KUM65345.1 - 8.7e-65 217.3 3.1 1.9e-64 216.2 2.1 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KUM65345.1 - 1.7e-21 76.4 0.3 4.9e-21 74.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM65345.1 - 2.3e-07 30.5 0.0 5.5e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 KUM65345.1 - 0.0057 15.5 0.1 0.017 14.0 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF3121 PF11319.3 KUM65345.1 - 0.0085 15.6 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3121) Prp19 PF08606.6 KUM65345.1 - 0.034 13.8 0.5 0.52 10.0 0.2 2.5 2 0 0 2 2 2 0 Prp19/Pso4-like Cut8_C PF08559.5 KUM65346.1 - 3.4e-51 172.8 0.0 4.4e-51 172.4 0.0 1.2 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 KUM65346.1 - 1e-14 53.9 1.3 2.1e-14 53.0 0.9 1.5 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 KUM65346.1 - 4.1e-12 45.9 4.4 7.6e-12 45.0 3.1 1.5 1 0 0 1 1 1 1 Cut8 proteasome-binding domain IKI3 PF04762.7 KUM65347.1 - 0 1115.5 0.0 0 1115.0 0.0 1.2 1 0 0 1 1 1 1 IKI3 family COX7C PF02935.11 KUM65348.1 - 1.2e-14 53.8 1.1 1.7e-14 53.3 0.8 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc DSPc PF00782.15 KUM65349.1 - 9.5e-27 93.1 0.0 1.4e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 KUM65349.1 - 0.015 14.1 0.0 0.02 13.8 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Y_phosphatase PF00102.22 KUM65349.1 - 0.021 14.1 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KUM65349.1 - 0.093 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family zf-DNA_Pol PF08996.5 KUM65349.1 - 0.16 11.3 0.4 11 5.2 0.1 2.2 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger Vfa1 PF08432.5 KUM65350.1 - 2e-63 213.6 14.3 2.3e-63 213.4 9.9 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 RNA_polI_A34 PF08208.6 KUM65350.1 - 0.0015 18.2 12.2 0.0023 17.6 8.4 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 GAGA_bind PF06217.7 KUM65350.1 - 0.079 12.9 6.3 0.082 12.8 4.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2201_N PF13203.1 KUM65350.1 - 0.1 11.7 5.3 0.11 11.6 3.7 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Ycf1 PF05758.7 KUM65350.1 - 0.16 9.6 9.1 0.17 9.5 6.3 1.0 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 KUM65350.1 - 0.16 9.9 13.8 0.17 9.8 9.5 1.0 1 0 0 1 1 1 0 CDC45-like protein CDC27 PF09507.5 KUM65350.1 - 1.2 8.3 23.2 1.6 7.8 16.1 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2894 PF11445.3 KUM65350.1 - 1.6 8.9 6.7 2 8.6 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) TP53IP5 PF15331.1 KUM65350.1 - 1.8 8.4 8.5 2.4 8.0 5.9 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Iron_permease PF04120.7 KUM65350.1 - 2.7 7.6 4.8 5.3 6.6 3.3 1.4 1 0 0 1 1 1 0 Low affinity iron permease UPF0560 PF10577.4 KUM65350.1 - 3.4 5.8 9.4 4.1 5.5 6.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF1510 PF07423.6 KUM65350.1 - 4.2 6.6 21.0 5.7 6.2 14.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Hid1 PF12722.2 KUM65350.1 - 5 4.6 11.3 6.1 4.3 7.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.7 KUM65350.1 - 7 6.4 11.7 9.5 6.0 8.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4407 PF14362.1 KUM65350.1 - 7 5.5 6.2 8 5.3 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIF_alpha PF05793.7 KUM65350.1 - 8.8 4.5 26.2 11 4.1 18.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Arylsulfotran_2 PF14269.1 KUM65351.1 - 1.8e-31 109.4 0.1 2.3e-31 109.0 0.1 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Abhydrolase_6 PF12697.2 KUM65353.1 - 1.6e-18 67.4 0.0 2e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM65353.1 - 2.3e-08 33.8 0.0 4.1e-08 33.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KUM65353.1 - 6e-06 26.0 0.0 1e-05 25.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KUM65353.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Ufd2P_core PF10408.4 KUM65354.1 - 4.4e-201 669.4 9.8 5.2e-201 669.1 6.8 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 KUM65354.1 - 1.4e-24 85.8 0.3 4.4e-24 84.2 0.2 1.9 1 0 0 1 1 1 1 U-box domain Peptidase_S8 PF00082.17 KUM65355.1 - 6.4e-28 97.6 2.2 6.4e-28 97.6 1.5 2.2 2 0 0 2 2 2 1 Subtilase family DUF1205 PF06722.7 KUM65355.1 - 0.0088 16.2 0.0 0.038 14.2 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1205) DUF1788 PF08747.6 KUM65355.1 - 0.06 13.2 0.0 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1788) DUF1977 PF09320.6 KUM65356.1 - 4.6e-28 97.5 0.0 8.6e-28 96.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 KUM65356.1 - 2.2e-22 78.5 0.5 4.2e-22 77.6 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain ADP_ribosyl_GH PF03747.9 KUM65356.1 - 0.0077 16.0 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Phage_tail_S PF05069.8 KUM65356.1 - 0.067 12.9 0.2 0.13 11.9 0.2 1.4 1 0 0 1 1 1 0 Phage virion morphogenesis family DUF2416 PF10315.4 KUM65357.1 - 0.0024 18.1 0.1 0.0031 17.7 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) DUF4536 PF15055.1 KUM65357.1 - 0.0062 16.5 0.3 0.016 15.2 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4536) CTP_transf_2 PF01467.21 KUM65358.1 - 1.4e-05 25.2 0.0 4.8e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 Cytidylyltransferase Ydc2-catalyt PF09159.5 KUM65360.1 - 1.1e-90 303.8 0.0 2.3e-90 302.8 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 KUM65360.1 - 0.00028 20.7 0.0 0.75 9.6 0.0 3.7 4 0 0 4 4 4 1 Poxvirus A22 protein SAP PF02037.22 KUM65360.1 - 0.0012 18.3 0.0 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 SAP domain Tcp11 PF05794.8 KUM65361.1 - 9.1e-122 406.9 0.0 2.3e-121 405.5 0.0 1.6 1 1 0 1 1 1 1 T-complex protein 11 Peptidase_M75 PF09375.5 KUM65361.1 - 0.008 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Imelysin Peptidase_S10 PF00450.17 KUM65362.1 - 9e-77 258.9 0.0 1.6e-76 258.1 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KUM65362.1 - 3e-05 24.0 0.0 0.00088 19.2 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cofilin_ADF PF00241.15 KUM65363.1 - 1.6e-10 40.9 0.3 7e-06 25.9 0.1 2.0 1 1 1 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein LEA_2 PF03168.8 KUM65364.1 - 0.00056 20.2 0.8 2.8 8.3 0.0 3.9 4 0 0 4 4 4 2 Late embryogenesis abundant protein DUF3712 PF12505.3 KUM65364.1 - 0.0043 17.0 0.5 0.058 13.4 0.2 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) OTCace_N PF02729.16 KUM65365.1 - 9.5e-44 148.5 0.0 1.9e-43 147.5 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 KUM65365.1 - 3.2e-42 144.0 0.0 5.1e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain KH_1 PF00013.24 KUM65366.1 - 5.3e-10 38.7 0.0 1.5e-05 24.5 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 KUM65366.1 - 1.3e-06 27.9 2.7 0.00034 20.1 0.1 3.2 4 0 0 4 4 4 2 KH domain ALS_ss_C PF10369.4 KUM65367.1 - 2.1e-19 68.9 0.0 3.9e-18 64.9 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 KUM65367.1 - 7.3e-11 41.3 0.1 1.4e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 KUM65367.1 - 2.8e-09 36.6 0.0 5.7e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 KUM65367.1 - 0.0092 15.6 0.1 1.8 8.3 0.0 2.5 2 0 0 2 2 2 2 ACT domain PPR_2 PF13041.1 KUM65368.1 - 2e-10 40.4 0.9 0.00033 20.5 0.0 4.0 3 1 1 4 4 4 2 PPR repeat family PPR_3 PF13812.1 KUM65368.1 - 4.3e-09 35.9 1.1 0.022 15.0 0.0 5.0 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR PF01535.15 KUM65368.1 - 2e-06 27.4 0.1 0.035 14.0 0.0 4.1 4 0 0 4 4 4 2 PPR repeat TPR_14 PF13428.1 KUM65368.1 - 0.082 13.5 0.9 0.83 10.4 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Helicase_C PF00271.26 KUM65369.1 - 4.8e-18 64.7 0.0 1.1e-14 53.9 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 KUM65369.1 - 3.2e-16 59.2 0.0 6.1e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SOG2 PF10428.4 KUM65370.1 - 1.9e-116 389.3 0.1 1.9e-116 389.3 0.1 2.4 3 0 0 3 3 3 1 RAM signalling pathway protein LRR_4 PF12799.2 KUM65370.1 - 1.6e-15 56.3 3.4 4.4e-09 35.7 2.1 3.4 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KUM65370.1 - 9.1e-12 44.5 4.4 2.2e-07 30.5 0.5 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KUM65370.1 - 1.4e-09 36.6 4.4 0.054 13.5 0.2 5.4 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 KUM65370.1 - 6.9e-06 25.4 3.0 6.4 7.4 0.1 5.0 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 KUM65370.1 - 0.11 12.5 4.6 17 5.8 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich repeat MRP-S25 PF13741.1 KUM65371.1 - 9.2e-90 300.1 4.0 1.1e-89 299.8 2.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 Motilin_assoc PF04643.7 KUM65371.1 - 0.07 12.6 1.1 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 Motilin/ghrelin-associated peptide FAD_binding_3 PF01494.14 KUM65372.1 - 3.5e-13 49.3 0.1 2.6e-12 46.5 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KUM65372.1 - 6.5e-06 26.3 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KUM65372.1 - 0.003 16.2 0.3 0.19 10.3 0.0 2.2 1 1 1 2 2 2 2 Tryptophan halogenase SE PF08491.5 KUM65372.1 - 0.011 14.5 0.0 2.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_8 PF13450.1 KUM65372.1 - 0.014 15.3 0.1 0.037 14.0 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KUM65372.1 - 0.016 14.1 0.8 1.3 7.8 0.0 2.2 1 1 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KUM65372.1 - 0.062 13.1 0.1 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3984 PF13136.1 KUM65373.1 - 9.6e-107 356.9 17.5 1.1e-106 356.7 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) TatD_DNase PF01026.16 KUM65374.1 - 2e-47 161.5 0.0 2.3e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Lactamase_B PF00753.22 KUM65375.1 - 0.0049 16.5 0.0 0.0062 16.1 0.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Asp PF00026.18 KUM65377.1 - 7.8e-75 252.0 4.1 7.8e-75 252.0 2.9 1.4 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KUM65377.1 - 1.7e-11 44.3 1.0 1.7e-10 41.0 0.1 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KUM65377.1 - 2.3e-05 24.8 0.0 0.2 12.1 0.0 2.9 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KUM65377.1 - 5.1e-05 22.8 0.1 0.00033 20.2 0.0 2.3 1 1 1 2 2 2 1 Xylanase inhibitor C-terminal SSP160 PF06933.6 KUM65377.1 - 0.066 11.1 17.7 0.1 10.5 12.3 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF515 PF04415.7 KUM65377.1 - 3.1 5.9 9.5 4.9 5.2 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) FMN_dh PF01070.13 KUM65379.1 - 2.3e-111 372.1 0.0 2.8e-111 371.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KUM65379.1 - 5.4e-19 67.7 0.0 1.6e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KUM65379.1 - 9.4e-05 21.4 0.0 0.00018 20.5 0.0 1.4 2 0 0 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.10 KUM65379.1 - 0.0015 17.7 0.1 0.73 8.9 0.0 2.2 1 1 1 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 KUM65379.1 - 0.0033 16.3 0.3 0.04 12.7 0.3 2.3 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 KUM65379.1 - 0.022 13.8 0.0 2.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DAG1 PF05454.6 KUM65379.1 - 0.05 12.7 0.0 0.08 12.1 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) zf-C2H2_4 PF13894.1 KUM65380.1 - 2.2e-06 27.5 23.8 0.0028 17.8 2.5 4.9 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.21 KUM65380.1 - 0.0014 18.8 23.8 0.033 14.5 2.0 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KUM65380.1 - 0.044 14.0 0.6 0.044 14.0 0.4 3.5 3 1 0 3 3 3 0 Zinc-finger double domain zf-CHCC PF10276.4 KUM65380.1 - 0.065 13.0 3.6 2.6 7.9 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger domain zf-C2H2_jaz PF12171.3 KUM65380.1 - 0.6 10.3 14.5 0.29 11.3 3.6 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-FCS PF06467.9 KUM65380.1 - 0.81 9.3 7.5 1.7 8.3 0.2 2.9 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif FMN_dh PF01070.13 KUM65383.1 - 2.6e-107 358.7 0.0 3e-107 358.5 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KUM65383.1 - 0.00011 21.2 0.1 0.00018 20.4 0.1 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 KUM65383.1 - 0.0031 16.8 0.5 0.062 12.5 0.0 2.1 1 1 1 2 2 2 1 Histidine biosynthesis protein Glu_synthase PF01645.12 KUM65383.1 - 0.013 14.4 0.1 0.018 13.9 0.1 1.1 1 0 0 1 1 1 0 Conserved region in glutamate synthase ThiG PF05690.9 KUM65383.1 - 0.064 12.3 0.6 0.63 9.0 0.2 2.1 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG NMO PF03060.10 KUM65383.1 - 0.68 9.0 3.1 1.2 8.1 2.2 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Steroid_dh PF02544.11 KUM65384.1 - 2.4e-16 59.8 0.9 5.5e-06 26.2 0.2 3.7 4 0 0 4 4 4 3 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KUM65384.1 - 0.02 14.2 1.1 0.053 12.8 0.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) Ldh_2 PF02615.9 KUM65387.1 - 6.3e-96 321.0 0.5 7.4e-96 320.7 0.0 1.3 2 0 0 2 2 2 1 Malate/L-lactate dehydrogenase adh_short PF00106.20 KUM65388.1 - 1e-09 38.5 0.0 4.5e-09 36.4 0.0 1.9 1 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KUM65388.1 - 0.00015 21.5 0.0 0.00021 21.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 KUM65388.1 - 0.0062 15.4 0.0 0.016 14.1 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.19 KUM65388.1 - 0.031 14.5 0.0 0.58 10.4 0.0 2.4 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KUM65388.1 - 0.15 12.0 0.0 0.69 9.8 0.0 2.0 2 0 0 2 2 2 0 NADH(P)-binding Fungal_trans PF04082.13 KUM65389.1 - 1.3e-10 40.6 0.4 2.4e-10 39.7 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM65389.1 - 1.5e-05 24.8 7.9 2.7e-05 23.9 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 KUM65390.1 - 2.9e-67 227.1 0.0 3.7e-67 226.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Dus PF01207.12 KUM65391.1 - 6e-39 133.7 0.0 1e-26 93.5 0.0 2.7 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 KUM65391.1 - 0.001 18.7 4.2 0.0013 18.3 0.2 2.4 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Peptidase_M24 PF00557.19 KUM65392.1 - 3.1e-19 69.4 0.0 3.5e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Bap31 PF05529.7 KUM65393.1 - 3.3e-65 219.1 0.1 4.1e-65 218.8 0.0 1.1 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like HALZ PF02183.13 KUM65393.1 - 0.0024 17.5 0.1 0.0049 16.5 0.0 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper Cluap1 PF10234.4 KUM65393.1 - 0.1 11.7 0.4 0.14 11.3 0.3 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 FlxA PF14282.1 KUM65393.1 - 0.19 11.6 1.6 0.34 10.8 1.1 1.4 1 0 0 1 1 1 0 FlxA-like protein DivIC PF04977.10 KUM65393.1 - 0.26 10.7 2.2 3.7 7.1 0.1 2.7 3 0 0 3 3 3 0 Septum formation initiator DUF1385 PF07136.6 KUM65393.1 - 3.5 6.6 5.5 3.2 6.7 3.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1385) p450 PF00067.17 KUM65394.1 - 2.3e-11 42.8 0.1 2.9e-11 42.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 KUM65395.1 - 9.1e-16 57.9 0.0 1.6e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM65395.1 - 1.6e-07 31.6 0.0 3.7e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM65395.1 - 1.9e-07 31.6 0.0 8.1e-07 29.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM65395.1 - 1e-06 29.1 0.0 2.2e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM65395.1 - 3.3e-05 23.5 0.0 7e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KUM65395.1 - 5.7e-05 23.1 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 KUM65395.1 - 0.001 18.5 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KUM65395.1 - 0.0019 18.5 0.0 0.015 15.6 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KUM65395.1 - 0.004 16.2 0.0 0.0081 15.2 0.0 1.5 1 1 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 KUM65395.1 - 0.0056 15.8 0.0 0.0091 15.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 KUM65395.1 - 0.0058 16.6 0.0 0.013 15.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KUM65395.1 - 0.084 11.9 0.0 0.57 9.2 0.0 2.1 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KUM65395.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TFIIA PF03153.8 KUM65396.1 - 8.5e-91 305.6 4.0 9.9e-91 305.4 2.8 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit GET2 PF08690.5 KUM65396.1 - 0.13 11.4 0.3 0.23 10.6 0.2 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 PAT1 PF09770.4 KUM65396.1 - 4.9 5.2 26.0 7.4 4.6 18.1 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-C2H2_4 PF13894.1 KUM65397.1 - 1.2e-05 25.2 10.3 0.047 14.0 0.4 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KUM65397.1 - 0.0003 20.9 12.6 0.051 13.9 1.1 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KUM65397.1 - 0.00084 19.4 1.9 0.044 13.9 0.1 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KUM65397.1 - 0.0056 16.9 13.2 0.0083 16.3 0.2 3.1 3 0 0 3 3 3 2 Zinc-finger double domain SprT-like PF10263.4 KUM65397.1 - 0.044 13.4 0.3 0.08 12.5 0.2 1.3 1 0 0 1 1 1 0 SprT-like family zf-C2H2_6 PF13912.1 KUM65397.1 - 8.8 6.3 6.4 0.51 10.3 0.3 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger Kelch_5 PF13854.1 KUM65398.1 - 9.7e-26 89.2 0.1 1.1e-05 25.2 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 KUM65398.1 - 3.8e-25 87.3 7.9 8e-07 28.7 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.1 KUM65398.1 - 9.6e-24 82.9 6.2 7.1e-08 32.4 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.1 KUM65398.1 - 1.9e-21 75.2 1.3 3.7e-05 23.6 0.0 4.9 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 KUM65398.1 - 5e-21 73.5 0.3 7.5e-06 25.5 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.20 KUM65398.1 - 5.8e-18 64.1 0.1 0.00039 19.9 0.0 4.6 4 0 0 4 4 4 4 Kelch motif BTB PF00651.26 KUM65398.1 - 8.6e-09 35.3 0.0 1.5e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 KUM65398.1 - 0.22 11.3 0.0 0.51 10.1 0.0 1.6 1 0 0 1 1 1 0 BTB And C-terminal Kelch WD40 PF00400.27 KUM65399.1 - 5.6e-24 83.1 17.2 3.5e-06 26.6 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 KUM65399.1 - 5.2e-05 23.0 0.4 0.0042 16.8 0.1 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Amidase PF01425.16 KUM65401.1 - 8.1e-55 186.4 0.1 4.9e-48 164.0 0.1 2.1 2 0 0 2 2 2 2 Amidase MFS_1 PF07690.11 KUM65402.1 - 1.4e-28 99.6 32.6 1.4e-28 99.6 22.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2404 PF10296.4 KUM65404.1 - 0.0012 18.9 0.0 0.0046 17.0 0.0 1.9 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Phage_Mu_Gam PF07352.7 KUM65405.1 - 0.12 11.8 2.2 0.2 11.1 0.6 1.9 1 1 0 2 2 2 0 Bacteriophage Mu Gam like protein zf-C2H2_4 PF13894.1 KUM65406.1 - 6.5e-08 32.3 31.1 0.17 12.3 0.0 7.5 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2 PF00096.21 KUM65406.1 - 0.0062 16.8 29.9 1.6 9.2 0.5 6.7 7 0 0 7 7 7 4 Zinc finger, C2H2 type zf-Di19 PF05605.7 KUM65406.1 - 0.0064 16.5 21.4 0.31 11.2 0.5 4.8 4 0 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding Clusterin PF01093.12 KUM65406.1 - 0.04 12.7 0.5 0.063 12.0 0.4 1.3 1 0 0 1 1 1 0 Clusterin zf-C2H2_2 PF12756.2 KUM65406.1 - 0.28 11.3 7.0 0.63 10.1 0.4 3.3 3 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KUM65406.1 - 2.8 8.2 6.8 50 4.2 0.0 4.6 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 KUM65406.1 - 3.4 8.1 18.3 37 4.8 0.4 6.7 6 2 0 6 6 6 0 Zinc-finger double domain Utp11 PF03998.8 KUM65407.1 - 4.4e-57 193.7 30.1 5e-57 193.5 20.8 1.0 1 0 0 1 1 1 1 Utp11 protein PhoU PF01895.14 KUM65407.1 - 0.11 12.8 1.1 0.77 10.2 0.0 2.4 2 0 0 2 2 2 0 PhoU domain Sporozoite_P67 PF05642.6 KUM65407.1 - 0.21 9.4 3.1 0.35 8.6 2.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TMEM237 PF15383.1 KUM65407.1 - 0.78 8.8 4.4 1.3 8.1 3.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 237 Ndc1_Nup PF09531.5 KUM65407.1 - 6.5 5.0 5.5 9 4.5 3.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup VIT1 PF01988.14 KUM65407.1 - 7.4 5.9 5.7 16 4.9 4.0 1.5 1 0 0 1 1 1 0 VIT family Cmc1 PF08583.5 KUM65408.1 - 1.6e-17 62.9 2.3 3.1e-17 62.1 1.6 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 KUM65408.1 - 0.063 13.2 0.1 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 CHCH domain Arylsulfotran_2 PF14269.1 KUM65409.1 - 1.4e-54 185.3 5.0 1.9e-54 184.8 3.5 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KUM65409.1 - 4.3e-17 61.7 0.8 6.2e-16 57.9 0.6 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DSBA PF01323.15 KUM65409.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Glyco_hydro_47 PF01532.15 KUM65410.1 - 8.5e-140 466.3 0.0 9.7e-140 466.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TipAS PF07739.8 KUM65410.1 - 0.0075 16.5 0.0 0.024 14.9 0.0 1.9 1 0 0 1 1 1 1 TipAS antibiotic-recognition domain Histidinol_dh PF00815.15 KUM65411.1 - 4.6e-175 582.1 4.8 6.6e-175 581.6 3.3 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 KUM65411.1 - 6.5e-24 83.3 0.0 1.3e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 KUM65411.1 - 3.5e-11 43.2 0.2 9.4e-11 41.8 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase SIP PF04954.8 KUM65411.1 - 0.15 12.4 0.9 0.96 9.8 0.2 2.4 2 0 0 2 2 2 0 Siderophore-interacting protein CIAPIN1 PF05093.8 KUM65412.1 - 6.6e-36 122.3 3.0 1.1e-35 121.6 2.1 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis TFIID-31kDa PF02291.10 KUM65413.1 - 3.5e-31 107.6 0.0 2.3e-25 88.8 0.0 2.5 2 1 0 2 2 2 2 Transcription initiation factor IID, 31kD subunit Mucin PF01456.12 KUM65413.1 - 0.18 11.5 8.2 0.36 10.5 5.7 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Med3 PF11593.3 KUM65413.1 - 8 5.5 10.1 14 4.8 7.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal LNS2 PF08235.8 KUM65414.1 - 1.6e-71 238.9 0.0 2.5e-71 238.3 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 KUM65414.1 - 8.9e-39 131.5 0.0 5.4e-38 129.0 0.0 2.1 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 KUM65414.1 - 0.0011 18.4 0.0 0.091 12.1 0.0 2.6 3 0 0 3 3 3 1 HAD superfamily, subfamily IIIB (Acid phosphatase) CobT PF06213.7 KUM65414.1 - 0.023 13.8 14.4 0.042 12.9 10.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT AF1Q PF15017.1 KUM65414.1 - 0.2 11.5 11.0 0.48 10.3 7.7 1.6 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator Nop14 PF04147.7 KUM65414.1 - 0.2 9.5 14.0 0.28 9.0 9.7 1.2 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 KUM65414.1 - 8.2 4.7 16.5 14 4.0 11.4 1.2 1 0 0 1 1 1 0 Daxx Family TPR_11 PF13414.1 KUM65415.1 - 1.1e-11 44.2 5.5 3.9e-06 26.4 0.0 4.9 6 0 0 6 6 6 2 TPR repeat TPR_2 PF07719.12 KUM65415.1 - 5e-08 32.2 15.1 0.00012 21.6 0.0 6.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 KUM65415.1 - 5.7e-06 26.5 1.2 0.069 13.4 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KUM65415.1 - 0.00017 21.1 1.0 0.022 14.5 0.0 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 KUM65415.1 - 0.00018 20.9 9.3 0.0016 17.9 0.0 5.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 KUM65415.1 - 0.00026 21.5 13.2 0.028 15.0 0.3 5.6 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 KUM65415.1 - 0.00063 19.3 2.9 2.9 7.9 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 KUM65415.1 - 0.0024 17.7 6.6 1.1 9.2 0.1 4.5 4 1 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 KUM65415.1 - 0.011 16.2 10.1 10 7.0 0.2 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 KUM65415.1 - 0.045 13.8 0.0 3.7 7.7 0.0 3.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 KUM65415.1 - 0.7 10.4 6.9 0.41 11.2 1.9 3.1 3 0 0 3 3 1 0 Tetratricopeptide repeat Sod_Fe_N PF00081.17 KUM65417.1 - 7.2e-34 115.8 1.8 7.2e-34 115.8 1.3 1.9 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.13 KUM65417.1 - 9.3e-31 105.8 0.1 1.6e-30 105.0 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain ACPS PF01648.15 KUM65417.1 - 0.025 14.3 0.6 0.071 12.9 0.2 1.9 2 1 0 2 2 2 0 4'-phosphopantetheinyl transferase superfamily Sugar_tr PF00083.19 KUM65419.1 - 2.9e-83 279.9 30.8 3.5e-83 279.6 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM65419.1 - 8.3e-31 106.9 45.5 1.5e-21 76.5 14.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DAO PF01266.19 KUM65420.1 - 4.7e-55 186.9 0.0 5.5e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KUM65420.1 - 1.4e-05 25.1 0.2 0.012 15.4 0.0 2.9 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM65420.1 - 0.0022 17.7 0.2 0.96 9.2 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.17 KUM65420.1 - 0.0073 15.2 0.1 0.16 10.8 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KUM65420.1 - 0.01 15.8 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ldh_1_N PF00056.18 KUM65420.1 - 0.046 13.5 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KUM65420.1 - 0.15 12.5 0.0 0.45 10.9 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 KUM65420.1 - 0.21 11.2 0.1 0.42 10.2 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UNC-93 PF05978.11 KUM65421.1 - 4.2e-10 39.3 3.9 4.2e-10 39.3 2.7 2.7 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 KUM65421.1 - 9.8e-09 34.3 30.1 9.8e-09 34.3 20.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM65421.1 - 1.8e-05 23.4 10.3 1.8e-05 23.4 7.2 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter DUF1469 PF07332.6 KUM65421.1 - 0.14 11.9 0.0 0.14 11.9 0.0 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1469) Glyco_hydro_1 PF00232.13 KUM65423.1 - 4.6e-157 522.8 0.0 5.7e-157 522.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Mesothelin PF06060.7 KUM65423.1 - 0.26 9.2 0.0 0.48 8.4 0.0 1.3 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) Pkinase PF00069.20 KUM65424.1 - 8.5e-64 215.1 0.0 1.4e-63 214.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM65424.1 - 1.4e-35 122.6 0.0 2.9e-33 115.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM65424.1 - 4.5e-05 22.5 0.0 0.03 13.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 KUM65424.1 - 0.00028 20.2 0.0 0.00066 19.0 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KUM65424.1 - 0.00049 19.9 0.2 0.0081 15.9 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KUM65424.1 - 0.021 13.9 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KUM65424.1 - 0.11 11.8 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL CDC45 PF02724.9 KUM65424.1 - 1.4 6.8 6.0 2.4 6.0 4.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Zn_clus PF00172.13 KUM65425.1 - 5.8e-06 26.1 13.7 1e-05 25.3 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mei5 PF10376.4 KUM65426.1 - 0.11 12.0 8.5 0.41 10.1 5.9 2.1 1 1 0 1 1 1 0 Double-strand recombination repair protein Med4 PF10018.4 KUM65426.1 - 0.26 10.6 7.1 0.52 9.6 0.8 2.2 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 WD40 PF00400.27 KUM65427.1 - 6.1e-15 54.4 6.1 6.4e-08 32.1 0.1 4.6 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 KUM65427.1 - 2.4e-05 24.1 0.0 0.1 12.3 0.0 2.9 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KUM65427.1 - 0.0014 17.0 0.0 0.0057 14.9 0.0 1.9 2 1 0 2 2 2 1 Cytochrome D1 heme domain Sel1 PF08238.7 KUM65428.1 - 6.5e-37 125.1 43.9 2.5e-05 24.7 0.2 11.8 12 1 0 12 12 12 8 Sel1 repeat TPR_8 PF13181.1 KUM65428.1 - 0.011 15.4 0.8 21 5.1 0.0 4.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KUM65428.1 - 0.093 12.5 4.2 33 4.6 0.0 4.9 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.1 KUM65428.1 - 0.84 9.3 12.3 0.49 10.0 0.0 5.0 4 1 1 5 5 5 0 TPR repeat TPR_1 PF00515.23 KUM65428.1 - 4.6 7.0 13.0 8.3 6.2 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat RNA_pol_Rpb1_1 PF04997.7 KUM65429.1 - 1.4e-117 392.7 0.0 2.3e-117 392.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 KUM65429.1 - 5.3e-104 347.3 0.1 1e-103 346.4 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KUM65429.1 - 1.3e-68 230.1 0.0 2.9e-68 229.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 KUM65429.1 - 9.4e-63 211.3 0.7 2.1e-62 210.1 0.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 KUM65429.1 - 3.6e-45 153.5 0.0 9e-45 152.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 KUM65429.1 - 1.9e-43 147.3 9.4 1.2e-42 144.8 5.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 KUM65429.1 - 4.6e-38 129.2 0.1 1.3e-37 127.7 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 KUM65429.1 - 5.7e-10 38.4 204.2 0.038 14.1 8.4 14.6 10 3 7 17 17 17 12 RNA polymerase Rpb1 C-terminal repeat YorP PF09629.5 KUM65429.1 - 0.075 13.0 0.0 1.3 9.0 0.0 2.6 3 0 0 3 3 3 0 YorP protein DUF4162 PF13732.1 KUM65429.1 - 0.16 12.5 1.2 0.71 10.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) Thg1C PF14413.1 KUM65430.1 - 9.4e-54 180.2 0.9 1.3e-53 179.8 0.7 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 KUM65430.1 - 3.6e-46 156.1 0.0 5.4e-46 155.5 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase fn3 PF00041.16 KUM65431.1 - 8.7e-07 28.9 0.0 2e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain WD40 PF00400.27 KUM65432.1 - 4.1e-16 58.1 1.5 1.5e-05 24.6 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 KUM65432.1 - 0.094 10.8 0.0 0.23 9.5 0.0 1.6 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DUF962 PF06127.6 KUM65432.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF962) Parvo_coat PF00740.13 KUM65433.1 - 6.9 5.5 8.0 7.7 5.3 5.5 1.3 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Lipase_GDSL_2 PF13472.1 KUM65435.1 - 2e-15 57.3 0.0 2.7e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KUM65435.1 - 1.4e-13 51.2 0.0 2.6e-13 50.3 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF993 PF06187.6 KUM65435.1 - 0.007 14.9 0.0 0.0093 14.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF993) AP_endonuc_2 PF01261.19 KUM65435.1 - 0.013 14.7 0.0 0.074 12.3 0.0 2.0 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Zn_clus PF00172.13 KUM65436.1 - 1.5e-07 31.2 16.0 2.5e-07 30.5 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CVNH PF08881.5 KUM65437.1 - 2.6e-22 78.9 0.1 4.3e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 CVNH domain Peptidase_C12 PF01088.16 KUM65438.1 - 1.9e-74 249.4 0.0 2.5e-74 249.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF4207 PF13904.1 KUM65438.1 - 0.068 12.5 0.4 0.11 11.8 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4207) Phosphoesterase PF04185.9 KUM65440.1 - 2.7e-72 244.0 4.8 4e-72 243.4 3.3 1.2 1 0 0 1 1 1 1 Phosphoesterase family GPI-anchored PF10342.4 KUM65441.1 - 0.00055 20.3 0.0 0.00091 19.6 0.0 1.5 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Cupin_8 PF13621.1 KUM65442.1 - 1.4e-33 116.4 0.0 4.2e-33 114.8 0.0 1.7 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KUM65442.1 - 5.2e-05 22.6 0.1 0.0075 15.5 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 KUM65442.1 - 0.05 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 JmjC domain, hydroxylase DUF1537 PF07005.6 KUM65443.1 - 7.5e-25 87.9 6.3 1.2e-24 87.2 4.4 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF1537 Cofilin_ADF PF00241.15 KUM65444.1 - 2.5e-24 85.5 1.3 2.8e-24 85.3 0.9 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Herpes_teg_N PF04843.7 KUM65444.1 - 0.0091 15.4 0.0 0.13 11.6 0.0 2.1 1 1 0 2 2 2 1 Herpesvirus tegument protein, N-terminal conserved region GTP1_OBG PF01018.17 KUM65445.1 - 7.2e-39 132.9 3.3 5.7e-29 100.7 2.1 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 KUM65445.1 - 1.2e-20 73.6 0.0 2.1e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KUM65445.1 - 1.6e-08 33.9 0.0 3.4e-08 32.9 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.22 KUM65445.1 - 0.0036 17.6 0.4 0.025 14.8 0.0 2.2 2 0 0 2 2 2 1 ABC transporter Dynamin_N PF00350.18 KUM65445.1 - 0.05 13.4 0.0 0.98 9.2 0.0 2.3 2 0 0 2 2 2 0 Dynamin family ArgK PF03308.11 KUM65445.1 - 0.061 12.0 0.1 0.35 9.6 0.0 1.9 2 0 0 2 2 2 0 ArgK protein Miro PF08477.8 KUM65445.1 - 0.083 13.3 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein GTP_EFTU PF00009.22 KUM65445.1 - 0.11 11.9 0.0 0.74 9.2 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF1014 PF06244.7 KUM65446.1 - 1.5e-24 86.5 16.4 6.8e-24 84.4 11.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) DUF3827 PF12877.2 KUM65446.1 - 8.8 4.2 12.7 13 3.6 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) CDC45 PF02724.9 KUM65447.1 - 6e-244 810.7 0.0 1.1e-243 809.8 0.0 1.8 1 1 0 1 1 1 1 CDC45-like protein Tir_receptor_N PF07490.6 KUM65447.1 - 0.011 15.4 0.8 0.03 13.9 0.6 1.7 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus DUF2360 PF10152.4 KUM65447.1 - 0.08 13.2 6.8 0.75 10.0 0.2 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Nop14 PF04147.7 KUM65447.1 - 0.16 9.8 25.7 0.095 10.6 5.3 2.1 2 0 0 2 2 2 0 Nop14-like family DUF2201_N PF13203.1 KUM65447.1 - 7.4 5.6 21.0 5.4 6.0 4.8 2.3 2 0 0 2 2 2 0 Putative metallopeptidase domain Peptidase_C13 PF01650.13 KUM65448.1 - 6e-40 137.1 0.1 8.2e-40 136.7 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family Pyr_redox_2 PF07992.9 KUM65450.1 - 1.1e-13 51.5 3.6 5.1e-08 33.0 0.0 3.5 1 1 2 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KUM65450.1 - 4.2e-13 49.4 0.5 1.4e-10 41.3 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KUM65450.1 - 1.3e-05 24.3 2.3 0.0012 17.8 0.0 3.2 2 1 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KUM65450.1 - 1.9e-05 24.8 2.1 0.29 11.1 0.0 3.3 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KUM65450.1 - 0.00012 21.3 0.0 0.009 15.1 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 KUM65450.1 - 0.00014 20.8 2.8 0.69 8.7 0.0 3.6 3 1 1 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 KUM65450.1 - 0.0097 14.8 0.2 1.6 7.5 0.0 2.5 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) MFS_1 PF07690.11 KUM65451.1 - 1.1e-38 132.8 22.3 4e-35 121.1 10.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KUM65451.1 - 2.2e-06 26.3 23.6 0.00053 18.4 11.4 2.3 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 KUM65451.1 - 0.00064 19.4 0.0 0.039 13.7 0.0 3.0 2 0 0 2 2 2 1 MFS_1 like family MFS_3 PF05977.8 KUM65451.1 - 0.0007 17.8 13.6 0.018 13.1 6.0 2.4 3 0 0 3 3 3 2 Transmembrane secretion effector VWA PF00092.23 KUM65453.1 - 1.5e-05 24.8 0.1 0.005 16.5 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.1 KUM65453.1 - 0.00015 21.9 0.0 0.00031 20.8 0.0 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain Fungal_trans_2 PF11951.3 KUM65454.1 - 1.3e-11 43.7 3.8 6.3e-10 38.2 2.7 2.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Attachment_P66 PF11263.3 KUM65454.1 - 0.16 10.9 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi attachment protein P66 GFA PF04828.9 KUM65455.1 - 0.0015 18.3 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_2 PF13240.1 KUM65455.1 - 0.058 12.8 0.5 0.16 11.5 0.3 1.7 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 KUM65455.1 - 0.17 11.1 0.3 0.17 11.1 0.2 1.7 2 0 0 2 2 2 0 zinc-ribbon domain Maf PF02545.9 KUM65456.1 - 5e-46 156.3 0.0 6.2e-46 155.9 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein eIF_4EBP PF05456.6 KUM65456.1 - 0.13 11.9 0.5 0.26 11.0 0.3 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) CybS PF05328.7 KUM65457.1 - 7e-50 168.0 0.0 9.5e-50 167.6 0.0 1.2 1 0 0 1 1 1 1 CybS ADH_zinc_N PF00107.21 KUM65458.1 - 3.1e-23 81.7 0.0 4.7e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KUM65458.1 - 2.6e-06 28.3 0.0 6.6e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KUM65458.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding p450 PF00067.17 KUM65459.1 - 2e-51 174.9 0.0 2.7e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Choline_kinase PF01633.15 KUM65460.1 - 3.5e-61 206.4 0.1 1.4e-60 204.4 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 KUM65460.1 - 1.9e-14 52.8 1.1 2.6e-14 52.3 0.0 1.8 2 0 0 2 2 2 1 Choline kinase N terminus APH PF01636.18 KUM65460.1 - 7.2e-09 35.7 0.7 2e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family WD40 PF00400.27 KUM65461.1 - 6.7e-29 98.6 21.7 4.7e-10 38.9 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Mem_trans PF03547.13 KUM65462.1 - 1.7e-56 191.2 0.0 2.3e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 Membrane transport protein TPP_enzyme_N PF02776.13 KUM65463.1 - 4.8e-32 110.8 0.3 7.1e-32 110.2 0.2 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KUM65463.1 - 1.8e-19 69.8 0.0 3.5e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KUM65463.1 - 4.9e-17 61.9 0.0 2.6e-16 59.5 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 KUM65463.1 - 0.16 10.6 0.0 0.34 9.5 0.0 1.5 1 0 0 1 1 1 0 Dehydrogenase E1 component DUF3950 PF13132.1 KUM65463.1 - 0.18 11.3 0.0 0.51 9.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3950) Sulfotransfer_3 PF13469.1 KUM65464.1 - 0.027 15.4 0.7 0.12 13.3 0.5 1.9 1 1 0 1 1 1 0 Sulfotransferase family Aminotran_1_2 PF00155.16 KUM65465.1 - 5.3e-16 58.5 0.0 6.2e-16 58.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HpcH_HpaI PF03328.9 KUM65466.1 - 1.4e-29 102.5 0.1 2.1e-29 102.0 0.1 1.4 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family YqaJ PF09588.5 KUM65466.1 - 0.092 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 YqaJ-like viral recombinase domain DEAD PF00270.24 KUM65467.1 - 8.8e-41 139.1 0.1 1.3e-40 138.6 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM65467.1 - 6.5e-19 67.5 0.3 1.8e-18 66.1 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KUM65467.1 - 0.0042 16.9 0.0 0.009 15.8 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 KUM65467.1 - 0.011 15.0 0.0 0.027 13.7 0.0 1.6 2 0 0 2 2 2 0 SecA DEAD-like domain Cys_Met_Meta_PP PF01053.15 KUM65468.1 - 2.9e-31 108.1 0.0 4.4e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KUM65468.1 - 7.4e-07 28.4 0.0 1.1e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DnaJ PF00226.26 KUM65469.1 - 1.4e-20 72.7 1.1 2.8e-20 71.8 0.7 1.5 1 0 0 1 1 1 1 DnaJ domain Adenylsucc_synt PF00709.16 KUM65470.1 - 7.3e-154 512.4 0.0 8.3e-154 512.2 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase MFS_1 PF07690.11 KUM65471.1 - 9e-40 136.4 10.3 7.7e-30 103.7 0.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM65471.1 - 2.1e-12 46.3 6.8 3.1e-11 42.5 4.3 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 KUM65471.1 - 6.9e-06 24.7 3.1 6.9e-06 24.7 2.1 2.8 2 1 0 2 2 2 1 MFS/sugar transport protein BT1 PF03092.11 KUM65471.1 - 0.0045 15.7 0.7 0.0045 15.7 0.5 1.9 1 1 0 2 2 2 1 BT1 family MFS_3 PF05977.8 KUM65471.1 - 0.13 10.3 10.0 0.036 12.1 2.5 2.5 2 1 0 2 2 2 0 Transmembrane secretion effector Fungal_trans PF04082.13 KUM65472.1 - 1.4e-28 99.5 0.0 2.4e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM65472.1 - 8.4e-09 35.2 11.3 1.3e-08 34.5 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HLH PF00010.21 KUM65473.1 - 3.7e-08 32.9 0.0 5.6e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Apc4 PF12896.2 KUM65474.1 - 1.9e-67 226.6 1.2 1.9e-67 226.6 0.8 1.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 4 Apc4_WD40 PF12894.2 KUM65474.1 - 1.1e-18 66.4 0.0 5.2e-17 61.0 0.0 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.27 KUM65474.1 - 0.0036 17.1 0.0 0.04 13.8 0.0 2.8 3 0 0 3 3 3 1 WD domain, G-beta repeat IKI3 PF04762.7 KUM65474.1 - 0.0087 13.9 0.0 1.1 6.9 0.0 2.1 2 0 0 2 2 2 2 IKI3 family HEAT PF02985.17 KUM65475.1 - 1.9e-14 52.3 10.6 0.0007 19.4 0.0 8.5 9 0 0 9 9 9 4 HEAT repeat HEAT_EZ PF13513.1 KUM65475.1 - 4.2e-13 49.3 13.4 2.6e-08 34.1 0.0 6.6 5 3 3 8 8 8 3 HEAT-like repeat HEAT_2 PF13646.1 KUM65475.1 - 1.7e-11 44.2 10.4 0.00012 22.2 0.0 5.6 2 2 3 5 5 5 3 HEAT repeats IBN_N PF03810.14 KUM65475.1 - 1.4e-08 34.5 1.9 2.5e-07 30.4 0.7 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_PBS PF03130.11 KUM65475.1 - 0.0057 17.0 0.2 32 5.3 0.0 5.0 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Arm PF00514.18 KUM65475.1 - 0.0083 15.9 1.8 3.3 7.6 0.2 4.1 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.2 KUM65475.1 - 0.09 12.7 0.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion CLASP_N PF12348.3 KUM65476.1 - 4.1e-05 23.0 1.4 0.0019 17.6 0.1 2.9 3 1 0 3 3 3 1 CLASP N terminal DUF3385 PF11865.3 KUM65476.1 - 0.0077 16.1 0.9 0.56 10.1 0.4 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) Adaptin_N PF01602.15 KUM65476.1 - 0.012 13.9 0.6 0.17 10.1 0.2 2.4 2 1 0 2 2 2 0 Adaptin N terminal region Cse1 PF08506.5 KUM65476.1 - 0.017 13.6 0.1 0.55 8.7 0.1 2.6 1 1 2 3 3 3 0 Cse1 Ribosomal_S8 PF00410.14 KUM65477.1 - 7e-24 84.1 0.0 9.5e-24 83.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 His_Phos_1 PF00300.17 KUM65478.1 - 3.1e-19 69.6 0.0 4.5e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF3340 PF11818.3 KUM65479.1 - 0.018 15.0 1.5 0.06 13.2 1.0 1.8 1 1 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) PS_Dcarbxylase PF02666.10 KUM65480.1 - 2.1e-82 275.3 0.0 4.5e-82 274.2 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Glyco_transf_90 PF05686.7 KUM65481.1 - 5.6e-19 68.1 4.3 1.8e-16 59.8 1.1 3.3 2 1 0 2 2 2 2 Glycosyl transferase family 90 Taeniidae_ag PF05596.6 KUM65481.1 - 0.0041 16.8 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 Taeniidae antigen Cu-oxidase_3 PF07732.10 KUM65482.1 - 7.2e-40 135.4 1.0 1.5e-36 124.7 0.0 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KUM65482.1 - 3.4e-31 107.5 6.0 7e-30 103.3 0.9 3.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 KUM65482.1 - 2.4e-18 66.5 0.3 1.3e-17 64.1 0.0 2.4 4 0 0 4 4 4 1 Multicopper oxidase COesterase PF00135.23 KUM65483.1 - 3.5e-72 243.8 0.0 4.6e-72 243.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KUM65483.1 - 1.5e-06 27.9 0.5 3.4e-06 26.7 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KUM65483.1 - 0.0066 15.6 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KUM65483.1 - 0.0075 16.1 0.2 0.033 14.0 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM65483.1 - 0.017 14.8 0.1 0.034 13.8 0.1 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1749 PF08538.5 KUM65483.1 - 0.16 10.8 0.0 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) PMP1_2 PF08114.6 KUM65484.1 - 0.11 12.0 0.6 0.32 10.5 0.0 2.1 2 0 0 2 2 2 0 ATPase proteolipid family DUF805 PF05656.9 KUM65484.1 - 3 7.7 10.9 11 5.8 3.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF805) Nop14 PF04147.7 KUM65486.1 - 0.98 7.2 24.7 1.5 6.6 17.1 1.2 1 0 0 1 1 1 0 Nop14-like family Neur_chan_memb PF02932.11 KUM65486.1 - 9.6 6.0 7.4 18 5.1 5.1 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Rrp15p PF07890.7 KUM65488.1 - 5.9e-33 113.6 5.1 5.9e-33 113.6 3.6 1.7 2 0 0 2 2 2 1 Rrp15p DUF1373 PF07117.6 KUM65488.1 - 0.17 11.5 0.1 0.17 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1373) SRP54 PF00448.17 KUM65489.1 - 1.8e-75 252.7 2.9 3.3e-75 251.8 2.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 KUM65489.1 - 2.1e-23 82.5 0.6 2.1e-23 82.5 0.4 4.3 4 1 0 4 4 2 1 Signal peptide binding domain SRP54_N PF02881.14 KUM65489.1 - 4.2e-16 58.8 0.6 8.5e-16 57.8 0.4 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 KUM65489.1 - 5.6e-10 38.9 0.3 1.4e-09 37.6 0.1 1.7 2 0 0 2 2 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KUM65489.1 - 5.6e-07 29.5 0.2 2.3e-06 27.5 0.1 2.0 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KUM65489.1 - 3.1e-05 23.6 0.1 8.6e-05 22.2 0.0 1.8 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_31 PF13614.1 KUM65489.1 - 3.2e-05 23.9 0.0 0.14 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KUM65489.1 - 3.4e-05 24.6 0.0 7.7e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 KUM65489.1 - 6.5e-05 22.4 0.5 0.00021 20.7 0.3 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.7 KUM65489.1 - 0.00031 19.9 0.1 0.00081 18.5 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin ArgK PF03308.11 KUM65489.1 - 0.00056 18.7 0.3 0.00056 18.7 0.2 2.5 2 1 0 2 2 2 1 ArgK protein APS_kinase PF01583.15 KUM65489.1 - 0.0006 19.4 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.1 KUM65489.1 - 0.00069 19.6 0.1 0.0018 18.2 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KUM65489.1 - 0.0027 17.8 0.1 0.0087 16.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain 6PF2K PF01591.13 KUM65489.1 - 0.0035 16.4 0.0 0.0062 15.6 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase SRPRB PF09439.5 KUM65489.1 - 0.004 16.4 1.4 1.6 7.8 0.1 3.0 2 1 1 3 3 3 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 KUM65489.1 - 0.0041 16.7 0.6 0.014 14.9 0.1 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Thymidylate_kin PF02223.12 KUM65489.1 - 0.0067 15.8 0.1 0.02 14.2 0.1 1.8 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 KUM65489.1 - 0.011 15.7 0.1 0.026 14.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KUM65489.1 - 0.011 16.0 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KUM65489.1 - 0.061 12.7 0.1 0.19 11.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain Arf PF00025.16 KUM65489.1 - 0.071 12.3 0.0 0.22 10.7 0.0 1.8 2 0 0 2 2 2 0 ADP-ribosylation factor family ABC_tran PF00005.22 KUM65489.1 - 0.081 13.2 0.8 0.4 10.9 0.0 2.3 2 1 0 2 2 2 0 ABC transporter VirE PF05272.6 KUM65489.1 - 0.086 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Virulence-associated protein E Mito_carr PF00153.22 KUM65490.1 - 9.2e-13 47.7 0.0 0.053 13.2 0.0 5.4 3 2 0 3 3 3 3 Mitochondrial carrier protein Herpes_UL32 PF06070.6 KUM65490.1 - 0.054 11.9 2.5 0.04 12.3 0.7 1.5 2 0 0 2 2 2 0 Herpesvirus large structural phosphoprotein UL32 Fer2 PF00111.22 KUM65491.1 - 7.3e-14 51.2 0.7 1e-13 50.7 0.5 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain PhoD PF09423.5 KUM65492.1 - 5e-57 193.4 0.0 6.9e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase fn3 PF00041.16 KUM65492.1 - 0.037 14.1 0.4 0.097 12.8 0.3 1.7 1 0 0 1 1 1 0 Fibronectin type III domain Glyco_hydro_18 PF00704.23 KUM65494.1 - 2.7e-10 40.2 0.0 7.5e-10 38.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Cellulase-like PF12876.2 KUM65494.1 - 0.081 13.3 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Sugar-binding cellulase-like DUF869 PF05911.6 KUM65497.1 - 1.6e-05 23.4 29.6 1.6e-05 23.4 20.5 3.0 2 1 0 3 3 3 2 Plant protein of unknown function (DUF869) DivIC PF04977.10 KUM65497.1 - 0.0027 17.1 4.8 0.0027 17.1 3.3 8.5 5 3 4 9 9 9 2 Septum formation initiator TMF_DNA_bd PF12329.3 KUM65497.1 - 0.0037 17.0 5.9 0.0037 17.0 4.1 8.6 4 2 6 10 10 10 2 TATA element modulatory factor 1 DNA binding MscS_porin PF12795.2 KUM65497.1 - 0.16 11.2 99.8 0.043 13.1 9.6 5.2 3 1 2 5 5 5 0 Mechanosensitive ion channel porin domain HOOK PF05622.7 KUM65497.1 - 0.98 7.1 67.8 0.0042 14.9 23.0 4.0 3 1 1 4 4 4 0 HOOK protein IncA PF04156.9 KUM65497.1 - 1 8.9 86.5 0.023 14.2 10.6 5.2 3 1 2 5 5 5 0 IncA protein GAS PF13851.1 KUM65497.1 - 1.1 8.4 65.3 0.11 11.6 13.3 5.5 4 1 1 5 5 5 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.6 KUM65497.1 - 4.8 6.9 79.3 1.8 8.3 3.5 5.1 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) TPR_11 PF13414.1 KUM65498.1 - 3.3e-07 29.8 0.0 8.7e-06 25.3 0.0 2.6 2 0 0 2 2 2 1 TPR repeat UBA PF00627.26 KUM65498.1 - 3.9e-05 23.3 0.0 9.1e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain TPR_2 PF07719.12 KUM65498.1 - 5.6e-05 22.7 0.7 0.47 10.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KUM65498.1 - 0.00015 22.3 0.9 0.059 14.0 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KUM65498.1 - 0.00055 19.4 0.1 7.3 6.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KUM65498.1 - 0.0029 17.5 0.6 0.062 13.2 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat GCD14 PF08704.5 KUM65499.1 - 2.5e-59 200.7 0.1 8.4e-59 199.0 0.0 1.9 2 1 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 KUM65499.1 - 0.0034 17.4 0.0 0.008 16.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain AdoHcyase PF05221.12 KUM65499.1 - 0.059 12.3 0.0 0.085 11.7 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase SGS PF05002.10 KUM65500.1 - 2.8e-25 87.8 0.8 8.3e-25 86.3 0.5 1.9 1 0 0 1 1 1 1 SGS domain CS PF04969.11 KUM65500.1 - 2.8e-16 59.8 0.2 4.5e-16 59.1 0.1 1.3 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 KUM65500.1 - 1.2e-06 28.0 4.3 1.2e-06 28.0 2.9 1.8 2 0 0 2 2 2 1 TPR repeat MIT PF04212.13 KUM65500.1 - 0.19 11.6 2.3 0.2 11.5 0.3 2.1 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_16 PF13432.1 KUM65500.1 - 0.25 12.0 8.6 0.59 10.8 2.7 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KUM65500.1 - 0.51 10.0 5.0 4.7 6.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 KUM65500.1 - 0.52 10.2 4.4 1.6 8.7 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KUM65500.1 - 0.94 9.5 8.6 6.6 6.9 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Prenyltrans PF00432.16 KUM65501.1 - 3.1e-30 103.4 8.6 6.3e-10 38.4 0.4 4.6 4 0 0 4 4 4 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 KUM65501.1 - 2.3e-24 85.4 0.0 3.9e-14 52.5 0.2 5.3 5 1 1 6 6 6 4 Prenyltransferase-like Prenyltrans_2 PF13249.1 KUM65501.1 - 2.9e-23 82.4 0.7 1.3e-12 48.1 0.3 4.9 3 1 1 4 4 4 3 Prenyltransferase-like Pec_lyase PF09492.5 KUM65501.1 - 8.6e-06 25.1 4.5 2.2 7.4 0.0 5.1 5 1 1 6 6 6 4 Pectic acid lyase ABC2_membrane PF01061.19 KUM65502.1 - 3.1e-92 307.4 56.8 2.3e-48 164.1 17.0 3.3 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KUM65502.1 - 2e-38 131.8 0.0 1.7e-18 67.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KUM65502.1 - 1.8e-36 123.8 4.4 8.9e-34 115.2 0.0 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 KUM65502.1 - 5.8e-22 77.5 0.1 1.6e-21 76.1 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KUM65502.1 - 5.7e-07 29.1 0.1 0.00025 20.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KUM65502.1 - 7.9e-06 25.1 0.2 0.006 15.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KUM65502.1 - 5.5e-05 23.2 1.0 0.0093 15.9 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 KUM65502.1 - 0.00029 20.3 0.9 0.015 14.7 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KUM65502.1 - 0.0003 20.6 0.1 0.26 11.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KUM65502.1 - 0.00046 19.6 3.0 0.02 14.3 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.14 KUM65502.1 - 0.0013 18.0 0.0 0.2 10.8 0.0 3.4 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 KUM65502.1 - 0.0047 17.2 1.3 0.32 11.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 KUM65502.1 - 0.0053 16.9 3.5 0.36 11.0 0.0 3.4 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KUM65502.1 - 0.0056 17.5 0.0 0.78 10.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 KUM65502.1 - 0.0063 15.5 45.1 0.08 11.9 10.3 2.9 3 1 0 3 3 3 2 ABC-2 family transporter protein NACHT PF05729.7 KUM65502.1 - 0.0065 16.1 3.6 2.7 7.6 0.0 3.3 3 0 0 3 3 3 2 NACHT domain AAA_19 PF13245.1 KUM65502.1 - 0.017 14.8 0.6 8.4 6.2 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 KUM65502.1 - 0.018 15.1 1.3 0.95 9.6 0.0 3.1 4 0 0 4 4 2 0 AAA domain AAA_21 PF13304.1 KUM65502.1 - 0.019 14.9 0.0 2.2 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KUM65502.1 - 0.028 14.9 0.1 4.5 7.7 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_10 PF12846.2 KUM65502.1 - 0.04 13.3 1.3 5.3 6.3 0.0 3.7 4 0 0 4 4 3 0 AAA-like domain Viral_helicase1 PF01443.13 KUM65502.1 - 0.052 13.0 0.5 3.7 7.0 0.0 2.6 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.1 KUM65502.1 - 0.074 13.0 0.5 1.2 9.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain Asp PF00026.18 KUM65503.1 - 2e-46 158.7 1.5 2.5e-46 158.3 1.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KUM65503.1 - 7.5e-06 26.3 1.9 0.028 14.9 0.4 4.4 3 2 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.1 KUM65503.1 - 0.00019 21.1 0.2 0.00065 19.4 0.1 2.0 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.1 KUM65503.1 - 0.0002 20.9 0.2 0.0059 16.1 0.1 2.6 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal RVP PF00077.15 KUM65503.1 - 0.022 14.6 0.0 0.17 11.8 0.0 2.4 3 0 0 3 3 3 0 Retroviral aspartyl protease CTV_P33 PF07184.6 KUM65504.1 - 0.026 13.3 0.1 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 Citrus tristeza virus P33 protein HlyIII PF03006.15 KUM65504.1 - 0.34 10.2 1.5 0.57 9.5 0.1 1.9 2 0 0 2 2 2 0 Haemolysin-III related p450 PF00067.17 KUM65505.1 - 3.3e-48 164.3 0.0 4.5e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.1 KUM65506.1 - 4.6e-65 219.8 48.7 5.7e-65 219.5 33.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM65506.1 - 1.7e-14 53.0 43.0 2.2e-14 52.6 29.8 1.1 1 0 0 1 1 1 1 Amino acid permease UPF0233 PF06781.7 KUM65506.1 - 2.1 8.0 7.5 1.2 8.8 1.8 3.0 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0233) MFS_1 PF07690.11 KUM65507.1 - 3.6e-20 72.0 29.5 3.6e-20 72.0 20.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily CENP-B_N PF04218.8 KUM65507.1 - 0.12 11.7 0.2 0.25 10.7 0.2 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain adh_short PF00106.20 KUM65508.1 - 2.2e-08 34.2 0.0 2.8e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM65508.1 - 0.00016 21.5 0.0 0.00029 20.6 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KUM65508.1 - 0.0079 15.3 0.2 0.011 14.9 0.1 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Ribonuc_L-PSP PF01042.16 KUM65509.1 - 3.3e-29 101.1 0.1 3.5e-29 101.0 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Abhydrolase_3 PF07859.8 KUM65510.1 - 2.6e-64 216.6 0.0 3.4e-64 216.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KUM65510.1 - 1e-10 41.2 0.0 1.6e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 KUM65510.1 - 1.9e-08 33.5 0.0 3.2e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 KUM65510.1 - 0.00011 21.0 0.0 0.00034 19.3 0.0 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KUM65510.1 - 0.00045 19.9 0.0 0.00066 19.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KUM65510.1 - 0.0032 16.3 0.0 0.0045 15.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DLH PF01738.13 KUM65510.1 - 0.035 13.3 0.0 0.071 12.3 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Glyco_hydro_43 PF04616.9 KUM65511.1 - 2.8e-58 197.3 5.4 3.6e-58 196.9 3.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 KUM65511.1 - 0.017 14.5 0.1 0.61 9.3 0.2 2.2 1 1 1 2 2 2 0 Glycosyl hydrolases family 32 N-terminal domain tRNA-synt_1e PF01406.14 KUM65512.1 - 5.5e-114 380.3 0.0 9.9e-114 379.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 KUM65512.1 - 1.6e-06 27.0 0.7 0.02 13.5 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.6 KUM65512.1 - 0.011 15.9 0.1 0.011 15.9 0.1 2.3 2 0 0 2 2 2 0 DALR domain Herpes_pp85 PF04637.7 KUM65512.1 - 0.079 11.2 0.0 0.15 10.3 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Transaldolase PF00923.14 KUM65513.1 - 3.2e-46 157.7 0.1 3.9e-46 157.4 0.1 1.1 1 0 0 1 1 1 1 Transaldolase ATP-sulfurylase PF01747.12 KUM65513.1 - 0.073 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 ATP-sulfurylase DUF505 PF04458.7 KUM65513.1 - 0.16 10.0 0.0 0.21 9.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF505) PQ-loop PF04193.9 KUM65514.1 - 2.4e-40 135.8 12.0 1.3e-20 72.6 1.2 2.7 2 0 0 2 2 2 2 PQ loop repeat DUF2721 PF11026.3 KUM65514.1 - 0.026 14.1 0.2 1.5 8.4 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) RskA PF10099.4 KUM65514.1 - 0.083 12.6 1.2 0.18 11.5 0.7 1.6 2 0 0 2 2 2 0 Anti-sigma-K factor rskA zf-HYPF PF07503.7 KUM65516.1 - 0.014 14.7 0.1 0.03 13.7 0.1 1.5 1 0 0 1 1 1 0 HypF finger TP6A_N PF04406.9 KUM65517.1 - 4.2e-10 39.1 0.4 7.7e-10 38.3 0.2 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF4599 PF15371.1 KUM65518.1 - 0.094 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4599) tRNA_int_endo PF01974.12 KUM65519.1 - 2e-20 72.3 0.1 4.7e-20 71.1 0.1 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 KUM65519.1 - 2e-06 27.2 0.0 0.0011 18.4 0.0 2.5 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain DUF1688 PF07958.6 KUM65520.1 - 8.9e-181 600.9 0.0 1e-180 600.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Gtr1_RagA PF04670.7 KUM65521.1 - 5.9e-94 313.5 0.3 7.2e-94 313.2 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 KUM65521.1 - 2.5e-08 33.3 0.0 3.4e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KUM65521.1 - 2.5e-08 33.4 0.0 3.9e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KUM65521.1 - 5.4e-06 26.8 0.0 1.1e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KUM65521.1 - 1.2e-05 25.2 0.0 2.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KUM65521.1 - 0.00058 19.3 0.0 0.0014 18.0 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 KUM65521.1 - 0.0029 17.0 0.3 0.0088 15.5 0.1 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.8 KUM65521.1 - 0.009 14.9 0.1 0.018 13.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 KUM65521.1 - 0.015 15.5 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 KUM65521.1 - 0.097 11.8 0.1 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NikR_C PF08753.6 KUM65521.1 - 0.13 12.1 0.0 17 5.3 0.1 2.6 2 0 0 2 2 2 0 NikR C terminal nickel binding domain G-alpha PF00503.15 KUM65521.1 - 0.14 10.7 2.5 2.7 6.5 0.8 2.2 1 1 1 2 2 2 0 G-protein alpha subunit AAA_10 PF12846.2 KUM65521.1 - 0.16 11.3 0.5 0.36 10.2 0.2 1.7 1 1 0 1 1 1 0 AAA-like domain AIG1 PF04548.11 KUM65521.1 - 0.28 10.2 1.4 0.37 9.8 0.3 1.9 2 1 0 2 2 2 0 AIG1 family Peptidase_M18 PF02127.10 KUM65523.1 - 1.3e-134 448.9 0.0 1.5e-134 448.7 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 KUM65523.1 - 0.025 13.3 0.0 0.6 8.8 0.0 2.3 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Nop10p PF04135.7 KUM65524.1 - 1.1e-20 73.0 1.2 2.1e-20 72.1 0.2 1.9 2 0 0 2 2 2 1 Nucleolar RNA-binding protein, Nop10p family NOB1_Zn_bind PF08772.6 KUM65525.1 - 2.6e-30 104.0 4.9 5.3e-30 103.0 3.4 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like Nop14 PF04147.7 KUM65525.1 - 0.042 11.7 8.9 0.071 11.0 6.1 1.3 1 0 0 1 1 1 0 Nop14-like family zf-NADH-PPase PF09297.6 KUM65525.1 - 0.095 12.2 1.2 0.38 10.3 0.1 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Senescence_reg PF04520.8 KUM65525.1 - 0.14 12.6 6.5 0.3 11.5 4.5 1.5 1 0 0 1 1 1 0 Senescence regulator ADH_N PF08240.7 KUM65526.1 - 1.3e-27 95.7 1.8 1.3e-27 95.7 1.2 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM65526.1 - 1.5e-05 24.5 0.0 0.0086 15.6 0.0 2.6 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KUM65526.1 - 0.00011 21.7 0.4 0.00048 19.7 0.3 2.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Hap4_Hap_bind PF10297.4 KUM65527.1 - 1.5e-08 34.2 7.0 1.5e-08 34.2 4.9 2.6 3 0 0 3 3 3 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 KUM65527.1 - 2e-08 34.0 7.1 1.6e-05 24.7 5.6 2.3 1 1 1 2 2 2 2 bZIP transcription factor Filament PF00038.16 KUM65527.1 - 0.0055 16.2 1.3 0.0086 15.5 0.9 1.3 1 0 0 1 1 1 1 Intermediate filament protein PNRC PF15365.1 KUM65527.1 - 0.014 15.4 0.6 0.014 15.4 0.4 3.9 3 0 0 3 3 3 0 Proline-rich nuclear receptor coactivator DUF2408 PF10303.4 KUM65527.1 - 0.022 14.8 0.3 0.038 14.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Tropomyosin_1 PF12718.2 KUM65527.1 - 0.048 13.5 2.0 0.082 12.7 1.4 1.3 1 0 0 1 1 1 0 Tropomyosin like FlaC_arch PF05377.6 KUM65527.1 - 0.065 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) bZIP_2 PF07716.10 KUM65527.1 - 0.14 11.9 9.2 0.33 10.8 6.2 1.8 1 1 0 1 1 1 0 Basic region leucine zipper FH2 PF02181.18 KUM65527.1 - 0.15 10.9 0.1 0.21 10.4 0.1 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain bZIP_Maf PF03131.12 KUM65527.1 - 1.6 9.0 7.7 0.071 13.4 1.0 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor Scramblase PF03803.10 KUM65528.1 - 1.8e-50 171.0 1.4 7.9e-24 83.9 0.0 3.0 2 1 0 2 2 2 2 Scramblase UQ_con PF00179.21 KUM65529.1 - 1.8e-50 169.9 0.0 2.1e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme AAA_12 PF13087.1 KUM65530.1 - 1.4e-37 129.0 0.0 2.4e-37 128.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KUM65530.1 - 1.1e-17 64.3 0.6 3.6e-17 62.7 0.0 2.0 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 KUM65530.1 - 3.9e-09 36.3 0.0 0.00014 21.5 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 KUM65530.1 - 7.9e-05 22.7 0.0 0.00021 21.4 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Rad9_Rad53_bind PF08605.5 KUM65532.1 - 1.6e-30 105.5 0.0 2.7e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 KUM65532.1 - 4.6e-07 29.8 0.0 4.4e-06 26.7 0.0 2.5 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DUF500 PF04366.7 KUM65533.1 - 1.1e-38 131.5 0.9 1.9e-38 130.7 0.7 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) GMC_oxred_C PF05199.8 KUM65534.1 - 3.5e-44 150.5 0.1 7.5e-44 149.5 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KUM65534.1 - 9.6e-42 143.1 0.0 2.4e-34 118.8 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.19 KUM65534.1 - 5e-07 28.9 0.1 2.2e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KUM65534.1 - 4.3e-06 26.7 0.0 2.4e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KUM65534.1 - 1.3e-05 24.3 1.0 3.9e-05 22.7 0.2 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KUM65534.1 - 4.5e-05 23.3 0.6 0.00013 21.9 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KUM65534.1 - 0.00031 19.7 0.1 0.0005 19.1 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 KUM65534.1 - 0.00042 19.3 0.4 0.0015 17.4 0.1 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 KUM65534.1 - 0.0023 17.0 0.1 0.0045 16.1 0.1 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KUM65534.1 - 0.0024 16.4 0.1 0.012 14.0 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 KUM65534.1 - 0.025 13.6 0.5 0.045 12.8 0.4 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KUM65534.1 - 0.033 14.2 0.8 6 6.8 0.2 2.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KUM65534.1 - 0.055 13.1 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 KUM65534.1 - 0.16 10.5 0.3 0.23 10.0 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.22 KUM65534.1 - 0.38 11.1 2.7 4.8 7.6 0.3 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_L27 PF01016.14 KUM65535.1 - 8.6e-28 95.9 0.1 1.6e-27 95.1 0.1 1.5 1 0 0 1 1 1 1 Ribosomal L27 protein DUF2076 PF09849.4 KUM65536.1 - 0.013 15.5 0.1 0.013 15.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Baculo_VP91_N PF08475.5 KUM65536.1 - 0.2 11.0 0.4 0.23 10.7 0.2 1.1 1 0 0 1 1 1 0 Viral capsid protein 91 N-terminal Atg14 PF10186.4 KUM65537.1 - 0.057 12.3 0.1 0.058 12.3 0.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 GFO_IDH_MocA PF01408.17 KUM65539.1 - 7.7e-22 78.0 0.1 1.2e-21 77.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 KUM65539.1 - 0.004 17.4 0.0 0.0074 16.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_18 PF00704.23 KUM65540.1 - 5.9e-48 164.0 10.6 1.1e-47 163.1 7.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 KUM65540.1 - 3e-08 33.3 0.3 8.4e-05 22.3 0.0 3.3 3 0 0 3 3 3 2 LysM domain Ank_2 PF12796.2 KUM65541.1 - 2.7e-30 104.5 4.9 8.2e-11 42.1 0.3 3.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KUM65541.1 - 1.8e-17 62.1 2.3 0.0036 17.0 0.0 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.1 KUM65541.1 - 8.5e-17 59.5 1.1 0.00093 19.2 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 KUM65541.1 - 3.6e-15 55.6 2.6 0.026 14.7 0.1 5.5 4 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 KUM65541.1 - 1.1e-14 54.4 1.9 0.00077 19.9 0.0 4.9 4 2 1 5 5 5 3 Ankyrin repeats (many copies) DUF3081 PF11280.3 KUM65541.1 - 0.043 13.3 0.1 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3081) Shigella_OspC PF06128.6 KUM65541.1 - 0.12 11.8 0.0 7.8 5.9 0.0 2.7 2 1 1 3 3 3 0 Shigella flexneri OspC protein DUF1593 PF07632.6 KUM65542.1 - 5.2e-93 311.1 0.3 8.5e-93 310.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) FAD_binding_3 PF01494.14 KUM65543.1 - 3e-07 29.8 0.0 3.2e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 KUM65543.1 - 0.012 14.4 0.0 0.014 14.1 0.0 1.1 1 0 0 1 1 1 0 Squalene epoxidase Ank_2 PF12796.2 KUM65544.1 - 4.6e-21 74.9 0.0 0.0032 17.7 0.0 6.1 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KUM65544.1 - 6.6e-20 71.0 0.6 0.082 13.4 0.0 9.0 8 2 1 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM65544.1 - 5.8e-19 67.6 1.6 0.0015 18.6 0.0 8.2 8 1 0 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.25 KUM65544.1 - 6.1e-17 60.5 0.0 0.0075 16.0 0.0 8.3 8 1 0 8 8 8 5 Ankyrin repeat Ank_3 PF13606.1 KUM65544.1 - 5e-08 32.4 1.3 50 4.5 0.0 9.9 10 1 0 10 10 10 0 Ankyrin repeat MFS_1 PF07690.11 KUM65545.1 - 8e-27 93.8 40.3 1.6e-25 89.5 16.3 2.7 1 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM65545.1 - 4.5e-08 32.1 0.2 4.5e-08 32.1 0.1 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter DUF1751 PF08551.5 KUM65545.1 - 0.8 10.0 9.6 0.036 14.4 2.0 2.3 2 1 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) zf-CCCH PF00642.19 KUM65547.1 - 1.2e-08 34.4 1.3 2.1e-08 33.6 0.9 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 KUM65547.1 - 1.6e-07 30.8 4.2 2.8e-07 30.0 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KUM65547.1 - 3.6e-07 30.1 9.9 6.2e-07 29.3 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KUM65547.1 - 5.4e-07 29.2 8.2 9e-07 28.5 5.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KUM65547.1 - 2.6e-06 27.1 7.2 4.4e-06 26.4 5.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KUM65547.1 - 5.3e-06 25.9 9.9 9.3e-06 25.2 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KUM65547.1 - 0.0034 17.2 8.3 0.0064 16.3 5.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KUM65547.1 - 0.041 13.6 5.5 0.09 12.5 3.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-Nse PF11789.3 KUM65547.1 - 0.081 12.4 2.4 0.16 11.5 1.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Cript PF10235.4 KUM65547.1 - 0.34 11.2 3.8 0.28 11.5 0.8 2.3 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT zf-rbx1 PF12678.2 KUM65547.1 - 2.9 8.0 6.2 11 6.2 4.3 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger Menin PF05053.8 KUM65547.1 - 5.3 5.0 6.9 6.8 4.7 4.8 1.1 1 0 0 1 1 1 0 Menin Mcp5_PH PF12814.2 KUM65548.1 - 8.8e-43 145.1 0.1 2e-42 143.9 0.1 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Methyltransf_23 PF13489.1 KUM65549.1 - 7.8e-14 51.7 0.0 1.2e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM65549.1 - 1.8e-08 34.7 0.0 3.4e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM65549.1 - 2.2e-05 24.9 0.0 3.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM65549.1 - 4.2e-05 23.9 0.0 0.00012 22.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM65549.1 - 0.0048 16.4 0.0 0.029 13.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KUM65549.1 - 0.022 13.7 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Ku PF02735.11 KUM65550.1 - 1.2e-37 129.3 0.0 2.8e-37 128.0 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KUM65550.1 - 1.1e-31 109.9 0.0 1.6e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 KUM65550.1 - 1.6e-11 44.6 0.0 4.5e-11 43.1 0.0 1.9 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 KUM65550.1 - 4.9e-10 38.6 0.0 9.9e-10 37.6 0.0 1.5 1 0 0 1 1 1 1 SAP domain VWA PF00092.23 KUM65550.1 - 0.0068 16.1 0.0 0.026 14.2 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain Fungal_trans PF04082.13 KUM65551.1 - 5.1e-15 55.0 0.6 8.7e-15 54.2 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 KUM65552.1 - 1.5e-70 238.0 0.0 1.7e-69 234.5 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KUM65552.1 - 2.8e-23 82.3 0.0 6.1e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_3 PF13738.1 KUM65552.1 - 0.012 15.6 0.0 0.048 13.7 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KUM65552.1 - 0.023 13.5 0.1 1.2 7.9 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KUM65552.1 - 0.035 13.0 0.0 0.07 12.0 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KUM65552.1 - 0.038 13.8 0.0 0.21 11.4 0.0 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 KUM65552.1 - 0.073 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase HI0933_like PF03486.9 KUM65552.1 - 0.073 11.5 0.0 0.12 10.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein DUF2316 PF10078.4 KUM65552.1 - 0.074 13.0 0.0 0.45 10.5 0.0 2.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2316) DUF3431 PF11913.3 KUM65553.1 - 3.5e-79 265.4 0.4 4.7e-79 264.9 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Ferrochelatase PF00762.14 KUM65554.1 - 8e-42 143.3 0.0 1e-41 142.9 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Exo_endo_phos PF03372.18 KUM65555.1 - 1.2e-20 74.5 0.1 1.9e-20 73.8 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2305 PF10230.4 KUM65557.1 - 1.4e-81 273.8 0.0 1.6e-81 273.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 KUM65557.1 - 2.2e-06 27.7 0.1 2.8e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM65557.1 - 0.00021 21.0 0.0 0.00048 19.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KUM65557.1 - 0.0018 17.8 0.0 0.0055 16.2 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1749 PF08538.5 KUM65557.1 - 0.0042 16.0 0.1 0.021 13.7 0.0 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1749) PGAP1 PF07819.8 KUM65557.1 - 0.014 14.9 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein LCAT PF02450.10 KUM65557.1 - 0.043 12.7 0.0 0.06 12.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF3089 PF11288.3 KUM65557.1 - 0.066 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF900 PF05990.7 KUM65557.1 - 0.12 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Rft-1 PF04506.8 KUM65557.1 - 0.16 10.2 0.0 0.23 9.7 0.0 1.1 1 0 0 1 1 1 0 Rft protein DCP1 PF06058.8 KUM65558.1 - 8.5e-19 67.8 0.0 1.2e-16 60.8 0.0 2.2 2 0 0 2 2 2 2 Dcp1-like decapping family DUF914 PF06027.7 KUM65559.1 - 1.8e-105 352.5 18.7 2.4e-105 352.0 13.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 KUM65559.1 - 1.5e-05 25.0 26.5 0.00018 21.5 7.2 2.8 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 KUM65559.1 - 0.0054 16.3 19.3 0.0057 16.3 3.3 2.5 2 0 0 2 2 2 2 Triose-phosphate Transporter family SMK-1 PF04802.10 KUM65560.1 - 2.8e-75 252.0 0.1 5.4e-75 251.1 0.1 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Chlam_vir PF05475.6 KUM65560.1 - 0.069 12.2 0.0 0.2 10.7 0.0 1.7 1 1 1 2 2 2 0 Chlamydia virulence protein PGP3-D PAP_assoc PF03828.14 KUM65561.1 - 5.5e-20 71.0 0.1 1.3e-19 69.8 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KUM65561.1 - 0.00026 21.2 0.0 0.00055 20.2 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Zwint PF15556.1 KUM65562.1 - 0.21 10.8 3.4 0.29 10.3 2.4 1.1 1 0 0 1 1 1 0 ZW10 interactor PPR_3 PF13812.1 KUM65563.1 - 0.00063 19.8 0.2 0.64 10.4 0.0 5.0 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 KUM65563.1 - 0.0025 17.7 0.1 0.72 9.8 0.0 3.7 3 0 0 3 3 3 1 PPR repeat family PPR PF01535.15 KUM65563.1 - 0.0088 15.9 0.8 3.4 7.8 0.0 4.1 4 0 0 4 4 4 1 PPR repeat Spo0A_C PF08769.6 KUM65563.1 - 0.029 14.2 0.1 0.071 12.9 0.0 1.6 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal TPR_19 PF14559.1 KUM65563.1 - 0.069 13.4 0.0 17 5.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat SE PF08491.5 KUM65564.1 - 2.1e-96 321.9 0.0 2.7e-96 321.6 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 KUM65564.1 - 1.3e-12 47.4 0.0 2.2e-06 26.9 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KUM65564.1 - 1.2e-09 37.6 0.2 1e-06 27.9 0.2 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 KUM65564.1 - 9.3e-05 21.6 0.1 0.00019 20.5 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KUM65564.1 - 0.00026 19.9 1.1 0.00041 19.3 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KUM65564.1 - 0.00048 20.4 0.2 0.0053 17.1 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KUM65564.1 - 0.00088 18.2 0.1 0.018 13.8 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KUM65564.1 - 0.0014 17.5 0.6 0.012 14.5 0.2 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KUM65564.1 - 0.0017 18.3 1.0 0.0035 17.3 0.7 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KUM65564.1 - 0.0022 17.1 0.4 0.0033 16.5 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KUM65564.1 - 0.0039 17.0 0.1 0.0069 16.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KUM65564.1 - 0.015 14.7 0.2 0.026 13.9 0.2 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 KUM65564.1 - 0.033 12.6 0.3 0.052 12.0 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.13 KUM65564.1 - 0.045 13.3 0.2 0.079 12.6 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 KUM65564.1 - 0.056 12.0 0.1 0.35 9.4 0.1 1.9 2 0 0 2 2 2 0 Tryptophan halogenase Shikimate_DH PF01488.15 KUM65564.1 - 0.068 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 KUM65564.1 - 0.079 12.6 0.1 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 KUM65564.1 - 0.19 11.1 0.3 0.38 10.1 0.1 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 KUM65564.1 - 0.28 11.0 1.6 0.49 10.2 1.1 1.3 1 0 0 1 1 1 0 ThiF family NmrA PF05368.8 KUM65565.1 - 2.1e-13 50.1 0.0 1.6e-10 40.6 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 KUM65565.1 - 0.00029 20.8 0.2 0.0006 19.8 0.2 1.5 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KUM65565.1 - 0.0082 14.8 0.0 0.013 14.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_3 PF00933.16 KUM65566.1 - 1.4e-88 296.7 0.0 2e-88 296.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KUM65566.1 - 4.6e-56 189.8 0.2 8.7e-56 188.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KUM65566.1 - 6.7e-24 83.6 0.0 1.4e-23 82.6 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Alpha-amylase PF00128.19 KUM65567.1 - 1.3e-16 60.9 1.8 3.9e-15 56.0 0.9 2.9 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 KUM65567.1 - 2e-14 53.7 0.1 3.5e-14 52.9 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 KUM65567.1 - 1.5e-09 38.1 0.0 3.3e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 KUM65567.1 - 2.9e-06 26.8 0.0 5.5e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 SH3_9 PF14604.1 KUM65568.1 - 4.7e-17 61.3 0.1 9.7e-17 60.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KUM65568.1 - 7.3e-14 50.8 0.1 1.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KUM65568.1 - 8.3e-11 41.2 0.1 1.3e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.13 KUM65568.1 - 7.7e-08 32.1 0.2 1.1e-07 31.6 0.2 1.2 1 0 0 1 1 1 1 BAR domain Apolipoprotein PF01442.13 KUM65568.1 - 0.00077 19.0 0.1 0.0019 17.7 0.0 1.9 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain GAS PF13851.1 KUM65568.1 - 0.0053 15.9 0.6 0.0083 15.3 0.4 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding MFS_1 PF07690.11 KUM65569.1 - 1.3e-42 145.8 45.6 2.8e-42 144.7 31.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM65569.1 - 7.9e-13 47.7 9.3 7.9e-13 47.7 6.5 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter FAD_binding_3 PF01494.14 KUM65570.1 - 2.5e-21 76.1 3.6 1.2e-19 70.5 2.5 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KUM65570.1 - 6.6e-10 38.4 0.0 1.2e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KUM65570.1 - 0.0002 21.6 0.2 0.0002 21.6 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM65570.1 - 0.00035 20.5 0.2 0.0011 18.9 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KUM65570.1 - 0.0015 18.4 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 KUM65570.1 - 0.0049 15.7 0.0 0.21 10.3 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase 3HCDH_N PF02737.13 KUM65570.1 - 0.0066 16.1 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 KUM65570.1 - 0.0091 14.5 0.3 0.013 14.0 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 KUM65570.1 - 0.0097 15.0 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 KUM65570.1 - 0.023 13.7 1.0 0.044 12.8 0.7 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KUM65570.1 - 0.058 12.2 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 KUM65570.1 - 0.089 12.5 0.7 0.24 11.1 0.2 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 KUM65570.1 - 0.22 10.8 0.6 0.38 10.0 0.4 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ketoacyl-synt PF00109.21 KUM65571.1 - 5.3e-65 219.4 0.3 1.1e-64 218.4 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KUM65571.1 - 1e-30 107.1 0.4 3.1e-30 105.5 0.1 1.9 2 0 0 2 2 2 1 Acyl transferase domain NAD_binding_4 PF07993.7 KUM65571.1 - 3.2e-26 91.7 0.0 5.1e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 KUM65571.1 - 4.7e-14 52.2 0.0 1.3e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KUM65571.1 - 4.5e-12 46.3 0.0 1.6e-11 44.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KUM65571.1 - 7.4e-11 42.1 0.1 1.9e-10 40.8 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 KUM65571.1 - 1.2e-09 37.9 0.0 2.8e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM65571.1 - 5.4e-08 33.3 0.0 4.1e-07 30.5 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM65571.1 - 2.9e-07 30.3 0.0 1.6e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Epimerase PF01370.16 KUM65571.1 - 6.9e-07 28.9 0.0 2.9e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.7 KUM65571.1 - 8.2e-07 29.4 0.0 3.1e-06 27.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM65571.1 - 6.1e-05 23.3 0.0 0.00022 21.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 KUM65571.1 - 0.00013 21.0 0.3 0.00037 19.5 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain adh_short PF00106.20 KUM65571.1 - 0.00014 21.8 0.3 0.0004 20.3 0.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase Methyltransf_26 PF13659.1 KUM65571.1 - 0.014 15.4 0.1 0.15 12.0 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_28 PF02636.12 KUM65571.1 - 0.031 13.6 0.0 0.082 12.2 0.0 1.7 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase UPF0054 PF02130.12 KUM65571.1 - 0.2 10.9 0.0 0.41 9.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein family UPF0054 zf-PHD-like PF15446.1 KUM65571.1 - 0.24 10.6 1.1 0.54 9.5 0.0 1.9 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain HSP20 PF00011.16 KUM65572.1 - 1.3e-17 63.5 0.1 1.8e-17 63.0 0.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Peptidase_S9 PF00326.16 KUM65573.1 - 3.7e-41 140.7 0.0 5.6e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KUM65573.1 - 5.4e-13 48.9 0.0 1.2e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KUM65573.1 - 2.5e-09 37.3 2.1 3.4e-08 33.6 1.4 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KUM65573.1 - 6e-09 35.4 0.2 4.2e-08 32.7 0.1 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_4 PF08386.5 KUM65573.1 - 2.3e-07 30.6 0.0 8.1e-07 28.8 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein BAAT_C PF08840.6 KUM65573.1 - 5.1e-07 29.6 0.0 0.0014 18.3 0.0 2.5 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.15 KUM65573.1 - 2.5e-06 27.1 0.0 5.8e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.13 KUM65573.1 - 7e-06 25.6 0.7 0.2 11.0 0.0 2.5 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.8 KUM65573.1 - 0.0001 21.9 0.2 0.00047 19.7 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 KUM65573.1 - 0.00042 19.8 0.0 0.00066 19.1 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 KUM65573.1 - 0.0008 19.0 0.1 0.33 10.4 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KUM65573.1 - 0.0055 16.1 0.0 0.067 12.6 0.0 2.5 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase_phd PF10503.4 KUM65573.1 - 0.014 14.6 0.5 2.8 7.1 0.4 2.4 2 1 0 2 2 2 0 Esterase PHB depolymerase OLF PF02191.11 KUM65573.1 - 0.055 12.7 0.0 0.48 9.6 0.0 2.0 2 0 0 2 2 2 0 Olfactomedin-like domain PD40 PF07676.7 KUM65573.1 - 2.1 8.0 5.5 12 5.6 0.1 2.8 3 0 0 3 3 2 0 WD40-like Beta Propeller Repeat DUF2439 PF10382.4 KUM65574.1 - 1.7e-29 101.8 0.6 2.6e-29 101.2 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Fungal_trans PF04082.13 KUM65575.1 - 1.2e-12 47.2 3.9 3.5e-12 45.7 2.7 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain ADH_N PF08240.7 KUM65576.1 - 3.4e-10 39.6 0.0 1.5e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM65576.1 - 1.8e-08 33.9 0.1 3.8e-08 32.9 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KUM65576.1 - 0.025 14.6 0.2 0.044 13.8 0.2 1.4 1 0 0 1 1 1 0 NADH(P)-binding DUF2001 PF09393.5 KUM65576.1 - 0.092 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2001) MFS_1 PF07690.11 KUM65577.1 - 2.6e-39 134.9 30.4 4.3e-39 134.2 21.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM65577.1 - 3.1e-12 45.8 10.7 3.1e-12 45.8 7.4 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter FAD_binding_3 PF01494.14 KUM65579.1 - 1.4e-78 264.4 0.0 6.2e-57 193.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Phe_hydrox_dim PF07976.7 KUM65579.1 - 7.6e-37 126.5 0.0 1.3e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.12 KUM65579.1 - 8.4e-05 21.7 0.0 0.00014 21.0 0.0 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KUM65579.1 - 0.00015 20.4 0.1 0.00022 19.8 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 KUM65579.1 - 0.00088 18.2 0.2 0.0062 15.4 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KUM65579.1 - 0.00088 18.2 0.0 0.0014 17.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KUM65579.1 - 0.0018 18.1 0.0 0.045 13.6 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM65579.1 - 0.0019 18.1 0.0 0.0051 16.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KUM65579.1 - 0.0065 15.5 0.0 0.0099 14.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KUM65579.1 - 0.0081 15.0 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 KUM65579.1 - 0.012 15.9 0.0 0.029 14.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF2199 PF09965.4 KUM65579.1 - 0.08 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) MMR_HSR1_C PF08438.5 KUM65581.1 - 3.5e-32 110.8 0.0 6.2e-32 110.0 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 KUM65581.1 - 3.2e-18 65.7 0.0 6.6e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KUM65581.1 - 1.4e-08 34.1 0.1 2e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KUM65581.1 - 0.0019 17.6 0.0 0.7 9.2 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KUM65581.1 - 0.0021 17.9 1.2 0.16 11.7 0.2 2.9 3 0 0 3 3 3 1 Dynamin family ATP_bind_1 PF03029.12 KUM65581.1 - 0.019 14.4 0.2 4.8 6.6 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ArgK PF03308.11 KUM65581.1 - 0.046 12.4 0.1 0.22 10.2 0.0 2.0 2 0 0 2 2 2 0 ArgK protein ABC_tran PF00005.22 KUM65581.1 - 0.093 13.0 0.0 0.49 10.6 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_10 PF12846.2 KUM65581.1 - 0.098 12.0 0.1 0.55 9.6 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain KTI12 PF08433.5 KUM65581.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SET PF00856.23 KUM65583.1 - 0.026 14.8 0.0 0.051 13.8 0.0 1.7 1 1 0 1 1 1 0 SET domain DUF3857 PF12969.2 KUM65583.1 - 0.035 13.6 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3857) Fungal_trans PF04082.13 KUM65584.1 - 6e-34 117.0 0.1 9.9e-34 116.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM65584.1 - 8.4e-09 35.2 14.7 1.4e-08 34.4 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3533 PF12051.3 KUM65585.1 - 5.3e-88 295.3 13.7 6.7e-88 294.9 9.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Nse5 PF08691.5 KUM65585.1 - 0.064 11.7 0.0 0.087 11.3 0.0 1.1 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 Sugar_tr PF00083.19 KUM65587.1 - 5.7e-135 450.3 24.3 6.5e-135 450.1 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM65587.1 - 1.4e-28 99.6 46.4 1e-21 77.0 15.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.7 KUM65587.1 - 0.0029 17.5 1.9 0.11 12.4 0.0 3.5 3 1 0 3 3 3 1 Poxvirus virion envelope protein A14 Spermine_synth PF01564.12 KUM65588.1 - 6.2e-97 323.3 0.0 7.5e-97 323.0 0.0 1.0 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 KUM65588.1 - 3.5e-05 23.4 0.0 5.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KUM65588.1 - 0.00011 22.2 0.0 0.0002 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM65588.1 - 0.00038 20.8 0.2 0.0043 17.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KUM65588.1 - 0.013 14.9 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 KUM65588.1 - 0.017 15.7 0.0 0.035 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KUM65588.1 - 0.074 13.5 0.0 0.22 12.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 KUM65588.1 - 0.099 11.8 0.3 0.39 9.8 0.1 2.0 1 1 1 2 2 2 0 O-methyltransferase Band_7 PF01145.20 KUM65590.1 - 7.9e-25 87.7 6.5 1e-24 87.4 4.0 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF2884 PF11101.3 KUM65590.1 - 0.0086 15.4 0.5 0.016 14.6 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) UcrQ PF02939.11 KUM65591.1 - 2.4e-29 100.9 0.1 2.9e-29 100.6 0.1 1.0 1 0 0 1 1 1 1 UcrQ family Fungal_trans PF04082.13 KUM65592.1 - 2.2e-18 66.1 0.7 4.6e-18 65.0 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain 3HCDH_N PF02737.13 KUM65593.1 - 5.2e-26 91.3 0.0 8.2e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KUM65593.1 - 2.3e-10 40.7 0.3 6.1e-10 39.3 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KUM65593.1 - 0.0071 16.1 0.0 0.018 14.9 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.9 KUM65593.1 - 0.067 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FMN_dh PF01070.13 KUM65594.1 - 1.8e-121 405.3 0.0 2e-121 405.1 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KUM65594.1 - 6.8e-05 21.9 0.2 0.00012 21.1 0.1 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KUM65594.1 - 0.00054 18.9 0.1 0.0008 18.4 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 KUM65594.1 - 0.0043 16.2 1.3 0.0054 15.9 0.3 1.5 2 0 0 2 2 2 1 Nitronate monooxygenase ThiG PF05690.9 KUM65594.1 - 0.037 13.0 6.2 0.75 8.8 0.3 2.5 2 1 1 3 3 3 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 KUM65594.1 - 0.04 13.1 0.3 0.56 9.4 0.1 2.1 1 1 1 2 2 2 0 Histidine biosynthesis protein Grp1_Fun34_YaaH PF01184.14 KUM65595.1 - 6.4e-82 273.9 13.0 7.7e-82 273.6 9.0 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family CAML PF14963.1 KUM65595.1 - 0.15 11.3 0.1 0.22 10.8 0.1 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand zf-C2H2_4 PF13894.1 KUM65596.1 - 1.5e-06 28.0 12.0 0.046 14.0 0.4 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KUM65596.1 - 0.0006 19.9 16.3 0.75 10.2 2.5 3.8 3 1 0 3 3 3 3 Zinc finger, C2H2 type Microtub_assoc PF07989.6 KUM65596.1 - 0.052 13.3 1.7 0.086 12.6 0.3 1.9 2 0 0 2 2 2 0 Microtubule associated zf-H2C2_5 PF13909.1 KUM65596.1 - 0.1 12.8 0.9 3.5 8.0 0.2 3.0 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Transpos_assoc PF13963.1 KUM65596.1 - 0.14 12.1 0.4 0.14 12.1 0.3 1.8 2 0 0 2 2 2 0 Transposase-associated domain zf-H2C2_2 PF13465.1 KUM65596.1 - 0.22 11.9 0.3 0.22 11.9 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger double domain DUF3115 PF11312.3 KUM65597.1 - 3.8e-104 347.9 0.0 5.1e-104 347.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) TPP_enzyme_N PF02776.13 KUM65598.1 - 1e-22 80.4 0.2 1.8e-22 79.6 0.2 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KUM65598.1 - 2.5e-11 43.4 0.0 5.3e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain adh_short PF00106.20 KUM65599.1 - 3.5e-15 56.3 0.1 5.7e-15 55.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM65599.1 - 1.6e-08 34.5 0.0 2e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM65599.1 - 0.0059 16.2 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 KR domain JmjC PF02373.17 KUM65601.1 - 1.7e-38 131.3 0.7 1.7e-38 131.3 0.5 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 KUM65601.1 - 6.4e-18 64.7 3.4 1.2e-17 63.8 2.4 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KUM65601.1 - 5.6e-17 61.6 4.0 1.4e-16 60.3 2.8 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.12 KUM65601.1 - 8.8e-17 60.3 0.3 2e-16 59.2 0.2 1.6 1 0 0 1 1 1 1 jmjN domain DUF2990 PF11693.3 KUM65602.1 - 0.067 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2990) p450 PF00067.17 KUM65603.1 - 2.8e-10 39.3 0.0 3e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 KUM65604.1 - 0.0014 18.1 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM65604.1 - 0.0021 17.8 0.0 0.004 16.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF2111 PF09884.4 KUM65604.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2111) 4HBT_2 PF13279.1 KUM65605.1 - 3.6e-09 37.1 0.0 5.4e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily FAD_binding_4 PF01565.18 KUM65606.1 - 6.9e-13 48.2 3.7 7.5e-13 48.1 1.7 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KUM65606.1 - 2.9e-07 30.3 0.3 6.6e-07 29.1 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.20 KUM65607.1 - 4.4e-24 85.2 0.0 6.1e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM65607.1 - 1.3e-13 51.2 0.0 1.7e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM65607.1 - 1.8e-08 34.2 0.0 3.2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 KR domain ERG4_ERG24 PF01222.12 KUM65608.1 - 3.1e-137 457.6 24.2 3.6e-137 457.4 16.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family OPT PF03169.10 KUM65609.1 - 3.2e-170 567.6 19.9 3.6e-170 567.4 13.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PAP2 PF01569.16 KUM65612.1 - 0.018 14.7 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 PAP2 superfamily Ribosomal_L7Ae PF01248.21 KUM65613.1 - 9.7e-19 66.6 1.5 9.7e-19 66.6 1.0 2.6 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family D5_N PF08706.6 KUM65613.1 - 0.077 13.0 3.3 0.092 12.8 1.7 1.5 1 1 0 1 1 1 0 D5 N terminal like RPA_interact_M PF14767.1 KUM65613.1 - 0.34 11.6 2.3 0.24 12.1 0.4 1.7 2 0 0 2 2 2 0 Replication protein A interacting middle MAD PF05557.8 KUM65614.1 - 1.5e-51 175.4 74.3 8e-43 146.5 51.9 2.0 2 0 0 2 2 2 2 Mitotic checkpoint protein NmrA PF05368.8 KUM65615.1 - 6.7e-15 54.9 0.0 9.2e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KUM65615.1 - 9.1e-11 42.0 0.0 1.3e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KUM65615.1 - 0.0022 17.0 0.0 0.0035 16.3 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 KUM65615.1 - 0.012 15.0 0.1 0.052 12.9 0.0 2.1 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KUM65615.1 - 0.016 13.8 0.0 0.11 11.1 0.0 2.2 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 KUM65615.1 - 0.044 13.7 0.2 0.11 12.4 0.0 1.8 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 KUM65615.1 - 0.08 13.2 0.1 0.18 12.0 0.0 1.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Fungal_trans PF04082.13 KUM65616.1 - 0.00047 19.1 0.0 0.00054 18.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain muHD PF10291.4 KUM65617.1 - 1.9e-79 266.4 0.0 2.8e-79 265.9 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 KUM65617.1 - 1.5e-10 41.1 0.0 6.4e-10 39.0 0.0 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain COG2 PF06148.6 KUM65617.1 - 0.081 12.7 1.0 0.33 10.8 0.2 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Pkinase PF00069.20 KUM65618.1 - 7.9e-44 149.7 0.0 1.1e-43 149.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM65618.1 - 1.2e-16 60.6 0.0 1.8e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KUM65618.1 - 8.7e-06 25.6 0.3 0.11 12.2 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KUM65618.1 - 7.3e-05 21.8 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KUM65618.1 - 0.0093 15.0 0.0 0.1 11.6 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KUM65618.1 - 0.06 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL SH3_9 PF14604.1 KUM65619.1 - 3.8e-07 29.5 0.0 6.9e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KUM65619.1 - 1.5e-05 24.3 0.0 3.1e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KUM65619.1 - 0.0001 21.7 0.0 0.00054 19.3 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain Rifin_STEVOR PF02009.11 KUM65619.1 - 0.0014 18.3 1.2 0.0014 18.3 0.0 1.5 2 0 0 2 2 2 1 Rifin/stevor family DUF2207 PF09972.4 KUM65619.1 - 0.017 13.7 0.4 0.023 13.2 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Plasmodium_Vir PF05795.6 KUM65619.1 - 3.5 6.7 5.4 8.6 5.4 3.8 1.6 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Mitofilin PF09731.4 KUM65619.1 - 6.9 5.1 12.2 0.23 10.0 3.9 1.7 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Sugar_tr PF00083.19 KUM65620.1 - 2.2e-106 356.1 14.4 2.7e-106 355.8 10.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM65620.1 - 3.7e-17 62.0 28.6 1.6e-13 50.0 3.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KUM65620.1 - 6.5e-05 21.1 1.2 0.00013 20.2 0.8 1.5 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family TPR_19 PF14559.1 KUM65620.1 - 0.045 14.0 0.0 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat AMP-binding PF00501.23 KUM65621.1 - 8.2e-86 287.9 0.0 1e-85 287.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KUM65621.1 - 7.3e-12 46.0 0.0 1.9e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Use1 PF09753.4 KUM65622.1 - 4.5e-07 29.5 8.6 1.1e-06 28.2 5.9 1.7 1 1 0 1 1 1 1 Membrane fusion protein Use1 IncA PF04156.9 KUM65622.1 - 0.35 10.4 0.0 0.35 10.4 0.0 2.7 2 1 1 3 3 3 0 IncA protein DUF572 PF04502.8 KUM65622.1 - 5.4 6.1 15.3 7.8 5.6 10.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) PEP-utilisers_N PF05524.8 KUM65622.1 - 5.9 6.7 10.2 2 8.2 1.1 2.8 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal IGPS PF00218.16 KUM65623.1 - 9.3e-98 326.3 0.0 2.5e-97 324.8 0.0 1.7 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 KUM65623.1 - 3.8e-60 202.8 0.0 5.4e-59 199.0 0.0 2.4 1 1 1 2 2 2 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 KUM65623.1 - 7.4e-51 172.3 0.0 1.6e-50 171.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KUM65623.1 - 9.5e-06 25.2 0.0 1.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 KUM65623.1 - 2.4e-05 23.9 0.4 0.0021 17.6 0.0 3.1 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain IMPDH PF00478.20 KUM65623.1 - 0.005 15.7 0.0 1.5 7.6 0.0 2.7 3 0 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 KUM65623.1 - 0.018 14.2 0.2 0.13 11.4 0.0 2.2 2 0 0 2 2 2 0 Histidine biosynthesis protein NanE PF04131.9 KUM65623.1 - 0.021 13.7 0.7 0.19 10.7 0.0 2.8 4 0 0 4 4 4 0 Putative N-acetylmannosamine-6-phosphate epimerase Nup188 PF10487.4 KUM65624.1 - 1.9e-57 194.9 0.0 3.2e-56 190.8 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 Brix PF04427.13 KUM65625.1 - 2.7e-45 154.4 0.0 3.4e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Brix domain PTCB-BRCT PF12738.2 KUM65626.1 - 2.6e-07 30.3 0.0 4.9e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KUM65626.1 - 7e-07 29.3 0.0 1.6e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain WGR PF05406.10 KUM65626.1 - 0.00055 19.8 0.4 0.0022 17.8 0.0 2.1 2 0 0 2 2 2 1 WGR domain DUF4396 PF14342.1 KUM65627.1 - 1.5e-23 83.4 5.4 2.4e-23 82.7 3.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) UPF1_Zn_bind PF09416.5 KUM65628.1 - 3e-73 244.4 1.1 3e-73 244.4 0.7 1.8 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 KUM65628.1 - 6.8e-60 201.8 0.0 1.2e-59 201.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KUM65628.1 - 4.9e-56 189.9 1.0 7.6e-56 189.3 0.7 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KUM65628.1 - 1.2e-14 53.8 0.3 3.1e-14 52.4 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KUM65628.1 - 4.9e-12 45.8 0.1 6.2e-11 42.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KUM65628.1 - 1.4e-08 34.7 0.0 2.7e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KUM65628.1 - 2.1e-05 24.1 0.1 0.32 10.4 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 KUM65628.1 - 0.00033 19.7 0.5 0.0036 16.3 0.0 2.7 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 KUM65628.1 - 0.00057 19.5 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 Helicase PIF1 PF05970.9 KUM65628.1 - 0.0024 16.8 0.1 0.46 9.3 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase UvrD-helicase PF00580.16 KUM65628.1 - 0.0031 16.8 0.0 0.034 13.4 0.0 2.4 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain DEAD PF00270.24 KUM65628.1 - 0.013 15.0 0.0 0.027 13.9 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.1 KUM65628.1 - 0.02 14.8 0.1 0.039 13.9 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain KaiC PF06745.8 KUM65628.1 - 0.045 12.8 0.0 0.081 12.0 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 KUM65628.1 - 0.062 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KUM65628.1 - 0.1 12.7 0.0 0.28 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 KUM65628.1 - 0.18 10.6 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 KUM65628.1 - 0.24 11.6 0.5 0.64 10.2 0.3 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HECT_2 PF09814.4 KUM65629.1 - 2.6e-87 292.8 0.0 3e-87 292.6 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.9 KUM65629.1 - 0.021 14.8 1.4 0.79 9.8 1.0 2.3 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TauD PF02668.11 KUM65630.1 - 3.4e-54 184.2 0.5 4e-54 183.9 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FAD_binding_2 PF00890.19 KUM65631.1 - 3.3e-126 421.5 3.5 4.1e-126 421.2 2.4 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 KUM65631.1 - 3.4e-46 156.2 1.6 5.1e-46 155.7 1.1 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 KUM65631.1 - 1.5e-08 34.8 0.0 0.0016 18.3 0.1 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KUM65631.1 - 7.5e-06 25.2 0.2 0.0082 15.2 0.0 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 KUM65631.1 - 1.1e-05 24.5 0.9 0.015 14.1 0.8 2.4 3 0 0 3 3 3 2 Glucose inhibited division protein A DAO PF01266.19 KUM65631.1 - 3.4e-05 22.9 0.5 0.00099 18.1 0.3 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KUM65631.1 - 0.0014 17.7 0.2 0.0029 16.7 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain PAPS_reduct PF01507.14 KUM65631.1 - 0.055 13.2 0.2 0.091 12.5 0.1 1.2 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family HI0933_like PF03486.9 KUM65631.1 - 0.25 9.7 2.2 0.79 8.1 0.4 2.4 3 0 0 3 3 3 0 HI0933-like protein Lyase_1 PF00206.15 KUM65634.1 - 8e-87 291.3 0.0 1.3e-86 290.6 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 KUM65634.1 - 1.5e-25 89.0 0.1 4.9e-25 87.3 0.1 2.0 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Membralin PF09746.4 KUM65634.1 - 0.12 11.3 0.0 0.25 10.3 0.0 1.5 1 1 0 1 1 1 0 Tumour-associated protein DPPIV_N PF00930.16 KUM65635.1 - 6.2e-110 367.1 0.0 9e-110 366.5 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KUM65635.1 - 2.5e-52 177.2 1.0 4.1e-52 176.4 0.7 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KUM65635.1 - 9.7e-08 31.8 0.0 1.9e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KUM65635.1 - 0.00042 19.8 2.9 0.0011 18.4 1.3 1.9 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 KUM65635.1 - 0.0011 18.8 0.1 0.0088 15.9 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 KUM65635.1 - 0.034 12.4 0.0 2.1 6.5 0.0 2.1 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II AXE1 PF05448.7 KUM65635.1 - 0.047 12.1 0.0 0.18 10.2 0.0 1.8 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 KUM65635.1 - 0.086 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cpn60_TCP1 PF00118.19 KUM65636.1 - 6.5e-120 400.9 7.4 8.1e-120 400.7 5.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3184 PF11380.3 KUM65636.1 - 0.048 11.6 0.7 0.067 11.1 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3184) Cpn60_TCP1 PF00118.19 KUM65637.1 - 1.9e-06 26.8 0.1 2.3e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Catalase PF00199.14 KUM65637.1 - 0.14 10.8 0.0 0.14 10.8 0.0 1.0 1 0 0 1 1 1 0 Catalase AAA PF00004.24 KUM65638.1 - 1.2e-40 138.8 0.0 2e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KUM65638.1 - 4.9e-06 26.7 0.0 0.0006 19.9 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 KUM65638.1 - 5.5e-05 22.9 0.1 0.0003 20.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KUM65638.1 - 0.00029 20.8 0.0 0.0015 18.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 KUM65638.1 - 0.00034 20.5 0.0 0.0011 18.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KUM65638.1 - 0.0017 17.3 0.0 0.0029 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KUM65638.1 - 0.0039 17.9 0.1 0.012 16.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KUM65638.1 - 0.0099 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KUM65638.1 - 0.01 15.5 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 KUM65638.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KUM65638.1 - 0.022 14.7 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KUM65638.1 - 0.032 13.8 0.1 0.61 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KUM65638.1 - 0.035 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KUM65638.1 - 0.049 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 KUM65638.1 - 0.065 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KUM65638.1 - 0.072 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 KUM65638.1 - 0.087 13.1 0.1 0.37 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 KUM65638.1 - 0.098 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 KUM65638.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein FR47 PF08445.5 KUM65639.1 - 1.5e-06 27.8 0.0 0.0016 18.1 0.0 2.3 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_3 PF13302.1 KUM65639.1 - 0.0055 16.8 0.0 0.009 16.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KUM65639.1 - 0.024 14.6 0.3 0.068 13.2 0.2 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family GlyL_C PF12524.3 KUM65639.1 - 0.028 14.3 0.3 0.093 12.6 0.0 1.9 2 0 0 2 2 2 0 dsDNA virus glycoprotein L C terminal Met_10 PF02475.11 KUM65641.1 - 6e-65 218.5 0.0 8.5e-65 218.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein RNA_pol_Rpb4 PF03874.11 KUM65642.1 - 2.3e-27 95.3 1.8 2.7e-27 95.0 1.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 AA_permease_2 PF13520.1 KUM65644.1 - 2.6e-54 184.4 52.4 3.2e-54 184.1 36.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM65644.1 - 1e-18 66.9 43.6 1.4e-18 66.4 30.2 1.1 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.16 KUM65644.1 - 0.26 11.1 0.0 0.26 11.1 0.0 3.7 6 0 0 6 6 6 0 Gram positive anchor DUF4243 PF14027.1 KUM65645.1 - 1.6e-68 231.6 0.0 1.9e-68 231.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DUF3818 PF12825.2 KUM65647.1 - 5.4e-139 462.6 1.4 7.5e-139 462.1 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 KUM65647.1 - 7.7e-41 138.9 0.2 1.7e-40 137.7 0.2 1.6 1 0 0 1 1 1 1 PX-associated PX PF00787.19 KUM65647.1 - 1.7e-15 56.7 0.7 7.7e-15 54.6 0.1 2.4 2 1 0 2 2 2 1 PX domain zf-C2H2 PF00096.21 KUM65648.1 - 0.00018 21.6 2.6 0.00018 21.6 1.8 3.5 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KUM65648.1 - 0.12 12.7 21.3 0.21 12.0 0.8 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KUM65648.1 - 0.14 12.5 18.8 1.7 9.0 2.5 3.7 3 0 0 3 3 3 0 Zinc-finger double domain zf-GRF PF06839.7 KUM65649.1 - 3.3e-07 30.1 5.7 6e-07 29.2 3.9 1.5 1 0 0 1 1 1 1 GRF zinc finger Ank_2 PF12796.2 KUM65650.1 - 5.3e-53 177.3 0.1 1.1e-13 51.3 0.0 6.0 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KUM65650.1 - 4.7e-45 149.2 0.5 2.9e-05 23.6 0.0 10.4 10 0 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.1 KUM65650.1 - 1.2e-39 134.0 0.6 1.8e-08 34.6 0.0 7.4 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM65650.1 - 5.8e-37 122.0 0.0 0.00087 19.3 0.0 10.2 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.1 KUM65650.1 - 1.3e-35 120.5 3.4 5.3e-10 39.2 0.0 8.6 3 2 6 9 9 9 8 Ankyrin repeats (many copies) AAA PF00004.24 KUM65651.1 - 8e-48 161.9 0.0 3.8e-43 146.8 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KUM65651.1 - 4.5e-05 22.9 0.1 0.00023 20.6 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 KUM65651.1 - 9.2e-05 23.2 0.0 0.0013 19.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KUM65651.1 - 0.0002 20.4 0.0 0.00045 19.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KUM65651.1 - 0.00034 20.7 0.0 0.0066 16.5 0.0 3.1 2 1 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.12 KUM65651.1 - 0.00048 19.0 0.0 0.0008 18.3 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_16 PF13191.1 KUM65651.1 - 0.00063 19.7 1.2 0.025 14.5 0.0 3.4 2 1 1 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.12 KUM65651.1 - 0.0015 18.0 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 KUM65651.1 - 0.0028 17.5 0.0 0.0078 16.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 KUM65651.1 - 0.0036 17.4 0.0 0.012 15.7 0.0 2.0 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 KUM65651.1 - 0.0055 15.4 0.0 0.0087 14.8 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 KUM65651.1 - 0.0068 16.1 0.0 0.028 14.1 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 KUM65651.1 - 0.023 14.4 0.0 0.075 12.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KUM65651.1 - 0.023 13.8 0.1 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 KUM65651.1 - 0.034 13.2 0.0 0.069 12.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.1 KUM65651.1 - 0.042 14.1 0.0 0.095 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KUM65651.1 - 0.046 12.9 0.0 0.085 12.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.1 KUM65651.1 - 0.055 13.3 0.1 0.28 11.0 0.0 2.3 3 0 0 3 3 1 0 AAA domain AAA_28 PF13521.1 KUM65651.1 - 0.063 13.2 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KUM65651.1 - 0.12 12.3 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KUM65651.1 - 0.14 11.7 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.12 KUM65651.1 - 0.22 10.0 0.0 0.35 9.4 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase Fungal_trans PF04082.13 KUM65652.1 - 8.7e-10 37.8 2.0 1.7e-09 36.9 1.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_10 PF00331.15 KUM65656.1 - 1.3e-69 234.7 0.0 1.5e-69 234.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.10 KUM65656.1 - 0.023 13.8 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase Fungal_trans PF04082.13 KUM65657.1 - 1.8e-23 82.7 0.1 3.7e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM65657.1 - 0.0013 18.5 6.4 0.003 17.4 4.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RIB43A PF05914.7 KUM65658.1 - 0.0045 15.6 0.3 0.007 15.0 0.2 1.2 1 0 0 1 1 1 1 RIB43A Ribosomal_L21p PF00829.16 KUM65658.1 - 0.047 13.8 0.0 0.072 13.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal prokaryotic L21 protein Ribosomal_S8e PF01201.17 KUM65659.1 - 1.7e-34 118.8 4.6 6.4e-34 116.9 3.2 1.8 1 1 0 1 1 1 1 Ribosomal protein S8e FHIPEP PF00771.15 KUM65659.1 - 0.44 8.8 1.8 0.57 8.4 1.3 1.1 1 0 0 1 1 1 0 FHIPEP family DUF2390 PF09523.5 KUM65659.1 - 2 8.6 6.4 4 7.6 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) Glyco_transf_28 PF03033.15 KUM65660.1 - 6.5e-24 84.2 0.0 1.6e-23 83.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KUM65660.1 - 0.0072 14.9 0.1 0.011 14.2 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase DUF1338 PF07063.8 KUM65661.1 - 2.6e-89 299.2 0.0 3e-89 299.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) Glycos_transf_1 PF00534.15 KUM65662.1 - 5e-12 45.5 0.0 1.3e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.3 KUM65662.1 - 2.4e-05 24.0 0.0 8e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3492) Glyco_trans_1_4 PF13692.1 KUM65662.1 - 0.00017 21.7 0.1 0.00064 19.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 GST_N_3 PF13417.1 KUM65664.1 - 4.8e-10 39.5 0.1 8.6e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KUM65664.1 - 3.1e-06 27.0 0.0 5.4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KUM65664.1 - 0.00015 21.7 0.0 0.00023 21.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KUM65664.1 - 0.0055 16.5 0.0 0.0096 15.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KUM65664.1 - 0.051 14.0 0.0 0.082 13.3 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PI-PLC-X PF00388.14 KUM65665.1 - 1e-56 190.3 0.0 2.7e-56 189.0 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KUM65665.1 - 6.5e-35 119.6 0.0 1.2e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Na_trans_assoc PF06512.8 KUM65665.1 - 2.8 7.8 6.3 0.83 9.5 1.9 1.8 2 0 0 2 2 2 0 Sodium ion transport-associated SoxD PF04267.7 KUM65666.1 - 0.025 14.3 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Sarcosine oxidase, delta subunit family MFS_1 PF07690.11 KUM65667.1 - 5.6e-24 84.5 21.0 5.6e-24 84.5 14.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KUM65667.1 - 0.0013 18.4 2.0 0.0023 17.6 0.2 2.4 2 0 0 2 2 2 1 MFS_1 like family DUF4500 PF14937.1 KUM65667.1 - 0.047 13.5 0.1 0.14 12.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) Glyco_hydro_114 PF03537.8 KUM65668.1 - 5.8e-24 83.6 0.1 1e-23 82.8 0.1 1.4 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Spherulin4 PF12138.3 KUM65669.1 - 4.6e-75 252.3 0.6 5.3e-75 252.1 0.4 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 MacB_PCD PF12704.2 KUM65669.1 - 0.014 15.0 0.8 0.15 11.6 0.4 2.3 2 1 0 2 2 2 0 MacB-like periplasmic core domain Epimerase PF01370.16 KUM65670.1 - 6.7e-35 120.6 0.0 3.3e-34 118.3 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 KUM65670.1 - 2.1e-12 46.7 0.1 4.3e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Polysacc_synt_2 PF02719.10 KUM65670.1 - 9.3e-09 34.5 0.0 9e-07 28.0 0.0 2.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KUM65670.1 - 5.7e-07 28.7 0.1 4.9e-06 25.6 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KUM65670.1 - 1.2e-06 27.5 0.0 1.4e-05 23.9 0.0 2.5 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KUM65670.1 - 3.3e-05 23.8 0.0 5.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM65670.1 - 0.00024 20.7 0.0 0.00043 19.9 0.0 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 KUM65670.1 - 0.00097 18.1 0.0 0.016 14.0 0.0 2.7 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KUM65670.1 - 0.042 13.8 0.0 0.64 10.0 0.0 2.6 3 1 0 3 3 3 0 NADH(P)-binding Ribosomal_L37 PF08561.5 KUM65671.1 - 4.9e-29 99.7 1.5 1.4e-22 79.0 0.2 2.2 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L37 KR PF08659.5 KUM65672.1 - 2e-33 115.5 0.0 5.8e-30 104.2 0.0 2.7 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 KUM65672.1 - 1.4e-31 109.6 0.0 5.5e-17 62.1 0.0 2.7 1 1 1 2 2 2 2 short chain dehydrogenase Methyltransf_23 PF13489.1 KUM65672.1 - 3e-13 49.8 0.0 5.4e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM65672.1 - 8e-13 48.7 0.1 5.6e-12 46.0 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM65672.1 - 3.6e-09 36.9 0.0 1.4e-08 35.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM65672.1 - 2.4e-06 27.2 0.0 6.6e-05 22.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM65672.1 - 0.00045 20.7 0.1 0.029 14.9 0.0 2.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KUM65672.1 - 0.0042 16.2 0.0 0.0077 15.3 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.10 KUM65672.1 - 0.02 14.4 0.1 0.12 11.9 0.0 2.0 1 1 1 2 2 2 0 Hypothetical methyltransferase MetW PF07021.7 KUM65672.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW RrnaAD PF00398.15 KUM65672.1 - 0.12 11.4 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.1 KUM65672.1 - 0.12 12.8 0.1 0.67 10.3 0.1 2.3 1 1 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 KUM65672.1 - 0.15 10.9 0.0 0.27 10.0 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase DUF4552 PF15089.1 KUM65672.1 - 0.3 9.9 0.0 0.54 9.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4552) FAD_binding_3 PF01494.14 KUM65673.1 - 1e-06 28.0 0.0 1.6e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pkinase PF00069.20 KUM65674.1 - 1.6e-47 161.8 0.0 2.3e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM65674.1 - 3.2e-16 59.1 0.0 5e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM65674.1 - 0.00031 19.7 0.0 0.0005 19.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KUM65674.1 - 0.003 16.9 0.1 0.0061 15.9 0.1 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KUM65674.1 - 0.039 13.6 0.0 0.22 11.2 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KUM65674.1 - 0.089 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KUM65674.1 - 0.14 11.7 0.2 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase PsaA_PsaB PF00223.14 KUM65674.1 - 0.24 9.4 0.0 0.35 8.8 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein PWI PF01480.12 KUM65675.1 - 3.4e-28 97.5 0.0 5.3e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 PWI domain NGP1NT PF08153.7 KUM65677.1 - 4.1e-47 159.3 0.1 6.3e-47 158.7 0.1 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 KUM65677.1 - 2.2e-19 69.5 0.0 5.4e-15 55.3 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KUM65677.1 - 1.3e-05 24.5 0.0 0.00012 21.4 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KUM65677.1 - 0.00018 21.3 0.1 0.24 11.1 0.0 3.5 2 1 1 3 3 3 1 Dynamin family Arf PF00025.16 KUM65677.1 - 0.00026 20.2 0.0 0.081 12.1 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family DUF258 PF03193.11 KUM65677.1 - 0.004 16.3 0.0 0.0076 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 KUM65677.1 - 0.028 14.9 0.0 6.9 7.1 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein SprA_N PF14349.1 KUM65677.1 - 0.031 13.5 0.3 0.05 12.8 0.2 1.2 1 0 0 1 1 1 0 Motility related/secretion protein GTP_EFTU PF00009.22 KUM65677.1 - 0.047 13.1 0.0 4.9 6.5 0.0 3.0 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain NACHT PF05729.7 KUM65678.1 - 4.3e-08 32.9 0.1 1.4e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 NACHT domain Ank_2 PF12796.2 KUM65678.1 - 1.6e-06 28.3 0.0 4.1e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KUM65678.1 - 6.9e-06 25.6 0.0 0.015 15.0 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat AAA_16 PF13191.1 KUM65678.1 - 7.2e-06 26.1 2.6 2.3e-05 24.4 0.0 2.9 3 1 0 3 3 2 1 AAA ATPase domain Ank_4 PF13637.1 KUM65678.1 - 1.3e-05 25.5 0.0 0.00018 21.9 0.0 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) AAA_22 PF13401.1 KUM65678.1 - 4.8e-05 23.5 1.3 0.00012 22.2 0.0 2.3 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.17 KUM65678.1 - 0.00025 20.0 0.2 0.0013 17.6 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain Ank_5 PF13857.1 KUM65678.1 - 0.00041 20.5 0.0 0.47 10.7 0.0 2.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) AAA PF00004.24 KUM65678.1 - 0.0016 18.6 0.4 0.0093 16.1 0.3 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Ank_3 PF13606.1 KUM65678.1 - 0.0026 17.8 0.0 1.5 9.3 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat AAA_14 PF13173.1 KUM65678.1 - 0.0049 16.7 0.1 0.1 12.5 0.0 2.7 2 1 0 2 2 1 1 AAA domain Arch_ATPase PF01637.13 KUM65678.1 - 0.0054 16.4 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 Archaeal ATPase AAA_33 PF13671.1 KUM65678.1 - 0.0078 16.0 0.0 0.024 14.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain PEPCK_ATP PF01293.15 KUM65678.1 - 0.019 13.4 0.2 0.029 12.9 0.1 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_29 PF13555.1 KUM65678.1 - 0.028 13.9 0.0 0.068 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SCO1-SenC PF02630.9 KUM65678.1 - 0.03 13.9 0.4 0.094 12.3 0.1 1.9 2 0 0 2 2 2 0 SCO1/SenC KAP_NTPase PF07693.9 KUM65678.1 - 0.036 13.0 0.1 0.22 10.4 0.0 1.9 1 1 0 2 2 2 0 KAP family P-loop domain Zeta_toxin PF06414.7 KUM65678.1 - 0.041 12.9 0.1 0.82 8.7 0.0 2.6 2 1 1 3 3 3 0 Zeta toxin AAA_17 PF13207.1 KUM65678.1 - 0.056 14.2 0.3 0.35 11.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain PIF1 PF05970.9 KUM65678.1 - 0.063 12.2 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase NTPase_1 PF03266.10 KUM65678.1 - 0.1 12.2 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.1 KUM65678.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KUM65678.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 KUM65678.1 - 0.13 12.5 0.1 0.49 10.6 0.0 2.0 2 0 0 2 2 1 0 ABC transporter MAT1 PF06391.8 KUM65679.1 - 3.3e-38 131.3 14.2 4.4e-38 130.8 9.8 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 KUM65679.1 - 0.0003 20.3 4.9 0.001 18.6 3.5 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KUM65679.1 - 0.00083 18.9 7.6 0.0018 17.8 5.2 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KUM65679.1 - 0.0023 17.9 6.6 0.0057 16.6 4.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KUM65679.1 - 0.0027 17.5 5.5 0.0053 16.5 3.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.1 KUM65679.1 - 0.0036 16.8 6.3 0.025 14.1 1.4 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 KUM65679.1 - 0.006 16.2 8.1 0.055 13.2 5.9 2.1 1 1 1 2 2 2 1 zinc-RING finger domain DUF572 PF04502.8 KUM65679.1 - 0.0074 15.5 8.9 0.0098 15.1 6.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Phage_B PF02304.10 KUM65679.1 - 0.2 11.9 5.7 0.21 11.8 2.1 2.2 2 0 0 2 2 2 0 Scaffold protein B Cep57_MT_bd PF06657.8 KUM65680.1 - 5e-28 96.8 0.2 5e-28 96.8 0.1 4.0 4 0 0 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 KUM65680.1 - 4.6e-20 71.3 12.9 4.6e-20 71.3 8.9 4.3 4 0 0 4 4 4 1 Centrosome localisation domain of PPC89 HALZ PF02183.13 KUM65680.1 - 0.014 15.1 2.5 0.014 15.1 1.8 3.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF720 PF05302.6 KUM65680.1 - 8.3 6.1 13.7 0.11 12.2 2.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF720) Peptidase_M6 PF05547.6 KUM65681.1 - 0.0053 14.8 0.6 0.0089 14.1 0.4 1.4 1 0 0 1 1 1 1 Immune inhibitor A peptidase M6 Peptidase_M7 PF02031.11 KUM65681.1 - 0.029 14.0 0.2 0.15 11.7 0.1 2.1 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family RNHCP PF12647.2 KUM65682.1 - 0.05 13.4 0.3 0.089 12.6 0.2 1.5 1 0 0 1 1 1 0 RNHCP domain Pkinase PF00069.20 KUM65683.1 - 2e-41 141.8 0.0 7.1e-41 140.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM65683.1 - 1e-28 100.1 0.0 1.4e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM65683.1 - 9.8e-06 24.7 0.0 3.9e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KUM65683.1 - 0.00067 18.7 0.0 0.0017 17.4 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KUM65683.1 - 0.0019 18.0 0.2 0.0091 15.7 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fungal_trans PF04082.13 KUM65684.1 - 3.2e-19 68.8 0.1 5.7e-19 67.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM65684.1 - 9.6e-08 31.8 8.9 1.7e-07 30.9 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KUM65685.1 - 3.6e-14 53.0 0.0 7.9e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM65685.1 - 2.4e-08 33.8 0.5 9.3e-08 31.9 0.1 1.9 2 0 0 2 2 2 1 KR domain Prefoldin_3 PF13758.1 KUM65686.1 - 6.9e-35 118.7 0.2 6.9e-35 118.7 0.1 2.0 2 0 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.2 KUM65686.1 - 1.4e-11 45.1 1.7 1.4e-11 45.1 1.2 6.3 7 2 1 8 8 8 2 Domain of unknown function (DUF3835) Prefoldin_2 PF01920.15 KUM65686.1 - 5.3 6.8 10.0 11 5.8 3.0 3.6 2 1 0 2 2 2 0 Prefoldin subunit HDV_ag PF01517.13 KUM65687.1 - 0.00026 20.7 0.1 0.00063 19.4 0.1 1.6 1 0 0 1 1 1 1 Hepatitis delta virus delta antigen zf-C2H2 PF00096.21 KUM65687.1 - 0.0054 17.0 3.1 0.21 12.0 0.1 2.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KUM65687.1 - 0.014 15.5 2.6 0.64 10.2 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KUM65687.1 - 0.067 13.3 1.5 3.9 7.6 0.4 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF629 PF04780.7 KUM65687.1 - 0.12 10.8 0.0 0.16 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.1 KUM65687.1 - 0.13 12.6 4.7 0.89 10.0 0.1 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KUM65687.1 - 0.4 10.6 2.2 6.1 6.8 0.0 2.4 1 1 1 2 2 2 0 C2H2-type zinc finger Tmemb_14 PF03647.8 KUM65688.1 - 6.5e-21 74.5 10.7 7.3e-21 74.3 7.4 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Zn_clus PF00172.13 KUM65689.1 - 0.0032 17.3 9.9 0.007 16.2 6.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_helicase PF00910.17 KUM65689.1 - 0.14 12.3 0.1 1.5 9.0 0.0 2.6 3 0 0 3 3 3 0 RNA helicase SurE PF01975.12 KUM65690.1 - 5.4e-46 156.3 0.0 7.8e-46 155.8 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Glyco_transf_28 PF03033.15 KUM65690.1 - 0.028 14.1 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain DUF2462 PF09495.5 KUM65692.1 - 1.3e-17 64.2 3.5 1.3e-17 64.2 2.4 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) tRNA-synt_1c PF00749.16 KUM65693.1 - 1.3e-94 316.4 0.0 1.7e-94 316.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KUM65693.1 - 2e-36 125.2 0.1 4.2e-36 124.2 0.1 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 KUM65693.1 - 3.1e-08 33.9 0.1 8.9e-08 32.5 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KUM65693.1 - 0.0028 17.6 0.0 0.0065 16.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KUM65693.1 - 0.019 14.8 0.1 0.048 13.5 0.1 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Fork_head_N PF08430.7 KUM65694.1 - 0.14 12.5 6.6 2.1 8.7 2.1 2.4 2 0 0 2 2 2 0 Forkhead N-terminal region API5 PF05918.6 KUM65694.1 - 0.31 9.4 2.8 0.48 8.8 1.9 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF2413 PF10310.4 KUM65695.1 - 3.5e-147 490.7 0.1 4e-147 490.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Flu_M1_C PF08289.6 KUM65695.1 - 0.12 12.4 0.3 0.12 12.4 0.2 2.2 2 1 1 3 3 3 0 Influenza Matrix protein (M1) C-terminal domain CMD PF02627.15 KUM65696.1 - 1e-07 31.7 0.0 1.7e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family IMS PF00817.15 KUM65698.1 - 5.8e-37 126.7 0.0 2.8e-36 124.5 0.0 2.0 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KUM65698.1 - 2.9e-13 49.8 0.0 5.7e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain AAA_12 PF13087.1 KUM65699.1 - 1.6e-41 141.8 0.0 2.7e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KUM65699.1 - 2.4e-24 86.2 0.2 1.7e-23 83.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KUM65699.1 - 7.4e-10 38.4 0.0 7.8e-09 35.1 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KUM65699.1 - 5.2e-08 32.6 0.0 1.4e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 KUM65699.1 - 0.00036 20.1 0.1 0.022 14.2 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 KUM65699.1 - 0.00054 19.8 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 KUM65699.1 - 0.006 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein UvrD_C_2 PF13538.1 KUM65699.1 - 0.023 14.8 0.0 0.056 13.5 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF2075 PF09848.4 KUM65699.1 - 0.056 12.4 0.0 0.33 9.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 KUM65699.1 - 0.059 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_25 PF13481.1 KUM65699.1 - 0.088 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3173 PF11372.3 KUM65700.1 - 0.14 11.7 0.0 6.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3173) adh_short PF00106.20 KUM65701.1 - 8.9e-26 90.7 0.5 1.6e-25 89.9 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM65701.1 - 1.1e-21 77.6 0.0 1.6e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM65701.1 - 1.3e-09 37.9 0.3 5.5e-09 35.9 0.2 1.8 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KUM65701.1 - 0.0048 15.8 0.0 0.0079 15.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_11 PF08241.7 KUM65701.1 - 0.13 12.7 0.1 0.35 11.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Amidase PF01425.16 KUM65702.1 - 1.8e-93 313.7 0.1 2.3e-93 313.4 0.1 1.1 1 0 0 1 1 1 1 Amidase DUF3445 PF11927.3 KUM65703.1 - 1.5e-76 257.1 0.0 1.9e-76 256.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) PRP38 PF03371.10 KUM65704.1 - 1.8e-66 222.9 0.0 2.2e-66 222.7 0.0 1.0 1 0 0 1 1 1 1 PRP38 family WD40 PF00400.27 KUM65706.1 - 8.6e-19 66.6 2.5 0.048 13.5 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat CDC45 PF02724.9 KUM65706.1 - 1.6 6.6 3.4 2.4 6.0 2.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 KUM65706.1 - 5.8 4.7 6.9 10 3.9 4.8 1.3 1 0 0 1 1 1 0 Nop14-like family Polysacc_deac_1 PF01522.16 KUM65707.1 - 5.8e-22 77.6 0.0 1.1e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Parvo_coat PF00740.13 KUM65707.1 - 0.012 14.5 0.1 0.017 14.1 0.0 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF2334 PF10096.4 KUM65707.1 - 0.018 14.4 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) DUF4110 PF13422.1 KUM65707.1 - 0.079 12.8 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) VDE PF07137.6 KUM65708.1 - 0.078 12.8 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Violaxanthin de-epoxidase (VDE) PBP_like PF12727.2 KUM65708.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 PBP superfamily domain Peptidase_C9 PF01707.11 KUM65708.1 - 0.11 12.0 0.1 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C9 APH PF01636.18 KUM65710.1 - 4.8e-07 29.7 0.7 0.008 15.9 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 KUM65710.1 - 1.3e-05 24.6 0.4 2.8e-05 23.5 0.2 1.6 1 1 1 2 2 2 1 RIO1 family Kdo PF06293.9 KUM65710.1 - 2.7e-05 23.3 0.2 7.5e-05 21.8 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 KUM65710.1 - 5.6e-05 22.4 0.1 7.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.15 KUM65710.1 - 0.00031 20.3 0.8 0.13 11.8 0.2 2.2 1 1 1 2 2 2 2 Choline/ethanolamine kinase Pkinase PF00069.20 KUM65710.1 - 0.0017 17.5 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RTA1 PF04479.8 KUM65711.1 - 2e-17 63.4 2.4 2.7e-17 63.0 1.6 1.3 1 0 0 1 1 1 1 RTA1 like protein Phage_holin_1 PF04531.8 KUM65711.1 - 0.0092 16.0 0.1 0.023 14.7 0.0 1.7 2 0 0 2 2 2 1 Bacteriophage holin MHYT PF03707.11 KUM65711.1 - 0.035 14.2 1.0 0.13 12.4 0.2 2.2 1 1 0 2 2 2 0 Bacterial signalling protein N terminal repeat Abi PF02517.11 KUM65711.1 - 3.8 7.7 6.2 9.1 6.4 4.3 2.0 1 1 0 1 1 1 0 CAAX protease self-immunity Oxidored_molyb PF00174.14 KUM65712.1 - 1.9e-47 160.8 0.0 3.3e-47 160.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 KUM65712.1 - 3.8e-36 123.6 0.1 8.9e-36 122.4 0.1 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.16 KUM65712.1 - 8.9e-24 84.1 5.0 1.9e-23 83.1 0.0 3.7 4 0 0 4 4 4 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 KUM65712.1 - 1.4e-19 69.6 0.1 3.5e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.19 KUM65712.1 - 3.1e-19 68.9 0.0 9e-19 67.4 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KUM65712.1 - 0.00039 20.3 0.0 0.024 14.5 0.0 2.8 1 1 1 2 2 2 1 Ferric reductase NAD binding domain WSC PF01822.14 KUM65713.1 - 2.3e-09 37.0 12.9 2.3e-09 37.0 9.0 2.7 2 1 0 2 2 2 1 WSC domain Rifin_STEVOR PF02009.11 KUM65713.1 - 0.0015 18.2 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 Rifin/stevor family Amnionless PF14828.1 KUM65713.1 - 0.019 13.4 0.0 0.027 12.9 0.0 1.2 1 0 0 1 1 1 0 Amnionless DUF2157 PF09925.4 KUM65713.1 - 0.028 14.0 3.2 0.084 12.4 0.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF2207 PF09972.4 KUM65713.1 - 0.028 13.0 0.1 0.049 12.2 0.0 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Adeno_E3_CR2 PF02439.10 KUM65713.1 - 0.11 12.0 0.8 0.25 10.9 0.6 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF3664 PF12406.3 KUM65713.1 - 0.84 10.2 5.0 1.6 9.3 3.5 1.4 1 0 0 1 1 1 0 Surface protein SKG6 PF08693.5 KUM65713.1 - 5.3 6.4 7.4 0.19 11.0 0.2 2.4 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Sugar_tr PF00083.19 KUM65714.1 - 2.6e-116 388.8 21.4 4.3e-116 388.1 14.8 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM65714.1 - 7.7e-26 90.6 38.9 1.6e-25 89.5 23.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily RTC4 PF14474.1 KUM65716.1 - 5.8e-35 119.9 0.0 1.1e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain SCIMP PF15050.1 KUM65716.1 - 6.8 6.5 7.0 1.3 8.9 1.3 2.3 2 0 0 2 2 2 0 SCIMP protein TFR_dimer PF04253.10 KUM65717.1 - 1.6e-17 63.2 0.0 2.7e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 KUM65717.1 - 4.7e-15 55.7 0.0 8.6e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KUM65717.1 - 1.7e-06 27.6 0.1 4.8e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.10 KUM65717.1 - 0.0035 16.6 0.0 0.0067 15.7 0.0 1.4 1 0 0 1 1 1 1 Nicastrin Homeobox_KN PF05920.6 KUM65718.1 - 3.2e-19 68.3 0.2 1.3e-18 66.3 0.2 2.2 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KUM65718.1 - 1.8e-05 24.2 0.1 5.9e-05 22.6 0.1 1.9 1 0 0 1 1 1 1 Homeobox domain PAT1 PF09770.4 KUM65720.1 - 3.1 5.9 21.8 4.5 5.3 15.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF726 PF05277.7 KUM65721.1 - 1.3e-127 425.4 2.9 1.8e-127 424.9 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Lipase_3 PF01764.20 KUM65721.1 - 0.011 15.3 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Fungal_trans PF04082.13 KUM65722.1 - 3.9e-07 29.2 0.5 6.5e-07 28.4 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM65722.1 - 0.0018 18.1 11.3 0.0028 17.5 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BatA PF07584.6 KUM65723.1 - 0.093 12.9 1.5 6.8 6.9 0.0 2.0 1 1 1 2 2 2 0 Aerotolerance regulator N-terminal Oxidored_q2 PF00420.19 KUM65723.1 - 0.16 11.5 3.6 0.18 11.3 2.5 1.2 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L NPCC PF08058.6 KUM65723.1 - 0.17 11.7 0.7 0.18 11.6 0.5 1.1 1 0 0 1 1 1 0 Nuclear pore complex component DUF2418 PF10332.4 KUM65723.1 - 0.21 11.9 2.1 0.23 11.7 1.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2418) Zn_clus PF00172.13 KUM65724.1 - 2.6e-05 24.0 2.2 5e-05 23.1 1.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KUM65724.1 - 0.011 14.3 0.1 0.021 13.4 0.0 1.5 2 0 0 2 2 2 0 Fungal specific transcription factor domain ATP-grasp_3 PF02655.9 KUM65724.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain RTA1 PF04479.8 KUM65725.1 - 4.8e-20 72.0 1.5 4.8e-20 72.0 1.0 1.4 2 0 0 2 2 2 1 RTA1 like protein DUF4131 PF13567.1 KUM65725.1 - 0.82 9.0 6.3 6.1 6.2 4.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) HNH_2 PF13391.1 KUM65726.1 - 6e-07 29.1 0.0 1.4e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease DUF2348 PF09807.4 KUM65727.1 - 2.4e-09 36.7 0.0 0.0015 17.7 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2348) KaiC PF06745.8 KUM65727.1 - 0.015 14.4 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 KaiC Fungal_trans PF04082.13 KUM65728.1 - 4.8e-33 114.1 0.2 7.1e-33 113.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM65728.1 - 3e-10 39.8 10.8 5e-10 39.1 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 KUM65728.1 - 3.9e-05 23.4 0.1 7.7e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 Gal4-like dimerisation domain Slu7 PF11708.3 KUM65729.1 - 1.3e-78 264.0 14.4 1.3e-78 264.0 10.0 2.1 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 KUM65729.1 - 0.022 14.4 0.7 0.042 13.5 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle PilN PF05137.8 KUM65729.1 - 0.087 12.6 0.3 0.22 11.3 0.2 1.7 1 0 0 1 1 1 0 Fimbrial assembly protein (PilN) Ribosomal_L37e PF01907.14 KUM65730.1 - 2e-27 94.7 12.5 2.9e-27 94.1 8.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 KUM65730.1 - 0.0012 18.5 3.0 0.0019 17.9 2.1 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 KUM65730.1 - 0.04 13.1 2.3 0.61 9.3 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 KUM65730.1 - 0.048 13.1 2.6 2.9 7.4 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain C1_1 PF00130.17 KUM65730.1 - 0.082 12.6 2.5 0.13 12.0 1.8 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_6 PF14599.1 KUM65730.1 - 0.39 10.5 2.3 0.53 10.1 1.6 1.2 1 0 0 1 1 1 0 Zinc-ribbon zf-HYPF PF07503.7 KUM65730.1 - 0.8 9.1 6.1 3.9 6.9 3.9 2.2 1 1 1 2 2 2 0 HypF finger zf-C3HC4_2 PF13923.1 KUM65730.1 - 1.3 9.1 5.0 2 8.4 3.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-CCHC_5 PF14787.1 KUM65730.1 - 1.6 8.2 7.2 1.1 8.8 3.8 1.7 1 1 0 1 1 1 0 GAG-polyprotein viral zinc-finger RdRP PF05183.7 KUM65731.1 - 9.3e-184 612.3 0.0 1.2e-183 611.9 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.17 KUM65731.1 - 8.8e-06 25.2 0.0 3e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM65731.1 - 0.0012 18.7 0.0 0.033 14.1 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WHIM1 PF15612.1 KUM65731.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 DNA_pol_B PF00136.16 KUM65732.1 - 3e-95 319.7 0.0 4.1e-95 319.2 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KUM65732.1 - 2.2e-20 72.8 0.0 5e-10 38.7 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KUM65732.1 - 1.2e-19 70.0 3.0 3e-19 68.7 2.1 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta FAD-oxidase_C PF02913.14 KUM65733.1 - 2.7e-63 213.6 0.0 3.6e-63 213.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KUM65733.1 - 3.9e-36 123.5 0.0 6.7e-36 122.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Baculo_p74 PF04583.7 KUM65734.1 - 0.063 12.4 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Baculoviridae p74 conserved region NmrA PF05368.8 KUM65735.1 - 6.1e-20 71.4 0.3 7.4e-20 71.1 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KUM65735.1 - 7.1e-15 55.4 0.5 8.2e-14 52.0 0.1 2.1 1 1 1 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 KUM65735.1 - 1.2e-08 34.3 0.3 2.2e-08 33.4 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 KUM65735.1 - 1.6e-05 25.2 1.9 2.8e-05 24.4 0.3 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KUM65735.1 - 0.00037 20.6 0.2 0.00093 19.3 0.1 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 KUM65735.1 - 0.00096 19.3 0.8 0.002 18.3 0.1 1.7 2 0 0 2 2 2 1 Putative NAD(P)-binding TrkA_N PF02254.13 KUM65735.1 - 0.0054 16.7 0.2 0.013 15.4 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain Gp_dh_N PF00044.19 KUM65735.1 - 0.014 15.3 0.2 0.04 13.8 0.1 1.8 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KUM65735.1 - 0.033 13.3 0.1 0.059 12.5 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KUM65735.1 - 0.068 12.9 1.2 0.96 9.1 0.8 2.3 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MtaB PF12176.3 KUM65735.1 - 0.074 11.4 0.0 0.12 10.8 0.0 1.3 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit ApbA PF02558.11 KUM65735.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 KUM65735.1 - 0.18 11.6 1.5 0.84 9.4 0.3 2.3 1 1 1 2 2 2 0 ThiF family Fungal_trans PF04082.13 KUM65736.1 - 2.9e-16 59.1 0.0 5.3e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ChaB PF06150.7 KUM65736.1 - 0.049 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 ChaB Peptidase_M20 PF01546.23 KUM65737.1 - 5.4e-27 94.5 0.0 9.1e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KUM65737.1 - 1.8e-10 40.5 0.1 3.6e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KUM65737.1 - 0.0025 17.6 0.0 0.0044 16.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 DUF1793 PF08760.6 KUM65738.1 - 8.6e-68 227.5 0.8 1.2e-67 226.9 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) Annexin PF00191.15 KUM65739.1 - 1.9e-12 46.8 4.4 0.00018 21.3 0.0 4.4 4 0 0 4 4 4 4 Annexin Septin PF00735.13 KUM65740.1 - 9.5e-35 119.9 0.0 7.3e-14 51.4 0.0 3.1 3 0 0 3 3 3 3 Septin MMR_HSR1 PF01926.18 KUM65740.1 - 0.00029 20.7 0.0 0.00064 19.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KUM65740.1 - 0.015 14.8 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family TEX19 PF15553.1 KUM65740.1 - 0.015 15.1 0.6 0.034 14.0 0.4 1.5 1 0 0 1 1 1 0 Testis-expressed protein 19 Dynamin_N PF00350.18 KUM65740.1 - 0.022 14.5 0.5 0.2 11.4 0.0 2.5 2 1 1 3 3 3 0 Dynamin family Miro PF08477.8 KUM65740.1 - 0.031 14.7 0.0 0.097 13.1 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein AAA_16 PF13191.1 KUM65740.1 - 0.058 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 KUM65740.1 - 0.072 13.3 0.1 0.76 10.0 0.2 2.2 2 0 0 2 2 2 0 ABC transporter DUF946 PF06101.6 KUM65741.1 - 7.7e-12 43.9 0.4 1.1e-11 43.4 0.3 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) NPP1 PF05630.6 KUM65741.1 - 0.037 13.7 0.7 0.058 13.1 0.5 1.2 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) MIP-T3 PF10243.4 KUM65743.1 - 0.018 13.5 36.1 0.024 13.0 25.1 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF605 PF04652.11 KUM65743.1 - 5.3 6.3 14.7 7.9 5.7 10.2 1.3 1 0 0 1 1 1 0 Vta1 like LpxC PF03331.8 KUM65744.1 - 0.076 11.9 0.1 0.13 11.1 0.1 1.3 1 0 0 1 1 1 0 UDP-3-O-acyl N-acetylglycosamine deacetylase ISG65-75 PF11727.3 KUM65744.1 - 0.092 11.7 5.5 0.028 13.4 0.9 1.9 2 0 0 2 2 2 0 Invariant surface glycoprotein CENP-F_leu_zip PF10473.4 KUM65744.1 - 0.14 12.0 14.0 0.11 12.3 3.2 2.5 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.7 KUM65744.1 - 0.22 11.3 4.2 0.72 9.6 0.9 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.16 KUM65744.1 - 0.35 10.2 13.4 1.5 8.1 1.9 2.2 2 0 0 2 2 2 0 Intermediate filament protein Bap31 PF05529.7 KUM65744.1 - 0.4 10.1 2.7 1.9 7.9 0.1 2.4 2 1 1 3 3 3 0 B-cell receptor-associated protein 31-like Tropomyosin_1 PF12718.2 KUM65744.1 - 0.69 9.7 14.5 1.4 8.7 10.1 1.6 1 0 0 1 1 1 0 Tropomyosin like TBPIP PF07106.8 KUM65744.1 - 0.69 9.4 10.8 0.27 10.7 2.6 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Prefoldin PF02996.12 KUM65744.1 - 0.84 9.2 8.1 0.63 9.7 0.9 3.2 2 2 1 3 3 3 0 Prefoldin subunit Med9 PF07544.8 KUM65744.1 - 1.3 8.8 6.4 1.3 8.7 1.0 3.3 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 AAA_13 PF13166.1 KUM65744.1 - 1.3 7.4 5.8 1.9 6.8 4.0 1.3 1 1 0 1 1 1 0 AAA domain DUF972 PF06156.8 KUM65744.1 - 1.4 9.3 8.7 3 8.2 0.3 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF972) BLOC1_2 PF10046.4 KUM65744.1 - 1.9 8.6 5.5 0.92 9.6 1.3 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4407 PF14362.1 KUM65744.1 - 2 7.3 8.9 3.1 6.6 6.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IncA PF04156.9 KUM65744.1 - 2.1 7.9 14.6 0.33 10.5 2.3 2.3 1 1 1 2 2 2 0 IncA protein Prefoldin_2 PF01920.15 KUM65744.1 - 2.1 8.1 11.9 0.66 9.7 1.2 3.4 2 1 1 3 3 3 0 Prefoldin subunit Mod_r PF07200.8 KUM65744.1 - 3 7.7 14.8 0.12 12.2 2.4 2.7 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Spc7 PF08317.6 KUM65744.1 - 3.3 6.2 11.5 1.1 7.8 2.3 2.2 1 1 0 2 2 2 0 Spc7 kinetochore protein Atg14 PF10186.4 KUM65744.1 - 4.6 6.0 10.1 0.86 8.4 1.5 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 HlyD PF00529.15 KUM65744.1 - 8.8 5.5 18.2 2.6 7.2 6.0 2.2 1 1 1 2 2 2 0 HlyD family secretion protein Ribosomal_S4 PF00163.14 KUM65745.1 - 6e-29 100.2 0.5 9.9e-29 99.5 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KUM65745.1 - 6.4e-13 47.9 0.7 6.4e-13 47.9 0.5 2.3 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 KUM65746.1 - 8e-39 131.4 3.3 8e-39 131.4 2.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L21e CEP1-DNA_bind PF09287.5 KUM65746.1 - 0.052 12.9 0.2 0.061 12.7 0.2 1.2 1 0 0 1 1 1 0 CEP-1, DNA binding WD40 PF00400.27 KUM65747.1 - 3.2e-56 185.3 18.0 4.9e-10 38.9 0.1 7.9 7 1 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KUM65747.1 - 2.9e-08 32.9 1.1 0.043 12.5 0.0 4.9 2 1 3 5 5 5 3 Nup133 N terminal like Nup160 PF11715.3 KUM65747.1 - 8.5e-06 24.1 10.9 0.27 9.3 0.0 5.5 3 3 3 6 6 6 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KUM65747.1 - 0.0013 18.2 4.2 0.25 10.7 0.2 3.0 2 1 0 2 2 2 2 PQQ-like domain CPSF_A PF03178.10 KUM65747.1 - 0.0021 17.2 0.1 0.015 14.4 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region PQQ_3 PF13570.1 KUM65747.1 - 0.057 13.7 4.7 7.2 7.0 0.0 4.6 5 1 0 5 5 5 0 PQQ-like domain DUF1399 PF07173.7 KUM65748.1 - 3.1e-20 72.8 0.0 6.7e-17 62.0 0.0 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF1399) Ras PF00071.17 KUM65749.1 - 4.7e-47 159.3 0.0 5.8e-47 159.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KUM65749.1 - 2e-13 50.8 0.0 2.8e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KUM65749.1 - 3.2e-09 36.2 0.0 4.4e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KUM65749.1 - 0.0012 18.0 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KUM65749.1 - 0.014 14.6 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PCI PF01399.22 KUM65750.1 - 1.8e-19 69.9 0.1 4.9e-19 68.6 0.1 1.8 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 KUM65750.1 - 5.3e-06 26.2 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Ipi1_N PF12333.3 KUM65750.1 - 0.008 16.1 0.6 1 9.3 0.0 3.2 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation Pyridox_oxidase PF01243.15 KUM65751.1 - 2.1e-13 50.1 0.0 4.8e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 KUM65751.1 - 0.016 15.0 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Colicin_C PF12106.3 KUM65751.1 - 2.2 7.9 8.2 0.24 11.0 0.5 2.9 3 0 0 3 3 3 0 Colicin C terminal ribonuclease domain BPL_LplA_LipB PF03099.14 KUM65752.1 - 1.5e-08 34.6 0.0 2.6e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF4066 PF13278.1 KUM65754.1 - 7.9e-17 61.0 0.0 1.2e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KUM65754.1 - 2.4e-11 43.2 0.0 3.1e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 KUM65754.1 - 0.019 14.3 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Peptidase_C65 PF10275.4 KUM65755.1 - 4.3e-32 111.4 0.0 5.3e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain Peptidase_C65 PF10275.4 KUM65756.1 - 1.9e-22 79.8 0.0 2.3e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain Sugar_tr PF00083.19 KUM65757.1 - 1.5e-118 396.2 19.7 2.5e-118 395.5 13.7 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM65757.1 - 1.9e-23 82.7 63.8 1.1e-18 67.1 23.0 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KUM65757.1 - 0.00015 20.1 1.5 0.00015 20.1 1.0 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) RRM_6 PF14259.1 KUM65759.1 - 1.8e-09 37.3 0.0 3.3e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KUM65759.1 - 1.1e-05 24.9 0.0 2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM65759.1 - 0.023 14.5 0.1 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CHC2 PF01807.15 KUM65760.1 - 0.021 14.3 0.1 0.37 10.3 0.0 2.3 2 0 0 2 2 2 0 CHC2 zinc finger DUF2797 PF10977.3 KUM65760.1 - 1.5 8.4 5.3 2.5 7.6 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) Semialdhyde_dhC PF02774.13 KUM65761.1 - 8.1e-35 120.3 0.0 1.1e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 KUM65761.1 - 3.4e-30 104.8 0.0 9.6e-30 103.3 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KUM65761.1 - 0.077 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ribosomal_S4e PF00900.15 KUM65762.1 - 2.5e-33 113.5 0.2 4.9e-33 112.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 KUM65762.1 - 2.1e-16 59.4 3.7 4.3e-16 58.4 2.5 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 KUM65762.1 - 6.7e-07 28.6 0.0 1.3e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 KUM65762.1 - 0.0055 16.3 1.4 0.0055 16.3 1.0 3.3 4 0 0 4 4 4 1 KOW motif RasGEF PF00617.14 KUM65763.1 - 1.5e-05 24.8 0.5 0.0001 22.1 0.0 2.4 3 0 0 3 3 3 1 RasGEF domain Myb_DNA-bind_6 PF13921.1 KUM65765.1 - 2.8e-16 59.3 0.0 2e-07 31.0 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KUM65765.1 - 1.5e-12 47.3 0.4 1e-05 25.4 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain PX PF00787.19 KUM65766.1 - 1e-25 89.6 0.2 1.2e-25 89.4 0.1 1.1 1 0 0 1 1 1 1 PX domain FAM91_N PF14647.1 KUM65766.1 - 0.1 11.6 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 FAM91 N-terminus WD40 PF00400.27 KUM65767.1 - 6.8e-19 66.9 18.1 2.8e-05 23.8 0.5 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KUM65767.1 - 4.6e-05 21.8 1.5 0.26 9.5 0.0 3.8 3 1 1 5 5 5 2 Cytochrome D1 heme domain PQQ_3 PF13570.1 KUM65767.1 - 0.0026 17.9 0.8 1.4 9.3 0.0 3.8 5 0 0 5 5 5 1 PQQ-like domain Nucleoporin_N PF08801.6 KUM65767.1 - 0.078 11.7 0.0 3.2 6.4 0.0 2.5 2 1 0 2 2 2 0 Nup133 N terminal like PPARgamma_N PF12577.3 KUM65767.1 - 0.22 11.8 3.2 20 5.5 0.5 3.0 2 1 0 2 2 2 0 PPAR gamma N-terminal region SecE PF00584.15 KUM65768.1 - 4e-13 48.7 0.0 4.9e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex CDP-OH_P_transf PF01066.16 KUM65769.1 - 4.8e-17 62.1 5.1 4.8e-17 62.1 3.5 2.8 2 2 0 2 2 2 1 CDP-alcohol phosphatidyltransferase NIPSNAP PF07978.8 KUM65770.1 - 9.5e-39 131.4 0.4 2.9e-27 94.6 0.0 2.4 2 0 0 2 2 2 2 NIPSNAP SCHIP-1 PF10148.4 KUM65770.1 - 0.059 12.7 0.8 0.092 12.1 0.5 1.2 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 FSH1 PF03959.8 KUM65771.1 - 4.9e-17 62.0 0.0 5.9e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Ribosomal_S27e PF01667.12 KUM65773.1 - 5.7e-29 99.4 6.6 7.4e-29 99.0 4.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 KUM65773.1 - 0.0043 16.8 1.2 0.005 16.6 0.8 1.2 1 0 0 1 1 1 1 IBR domain zf-CSL PF05207.8 KUM65773.1 - 0.11 12.0 0.8 0.2 11.1 0.6 1.5 1 0 0 1 1 1 0 CSL zinc finger MFS_1 PF07690.11 KUM65775.1 - 1e-22 80.3 24.6 1e-22 80.3 17.1 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM65775.1 - 0.00015 20.5 30.1 0.00057 18.5 20.9 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter UPF0016 PF01169.14 KUM65776.1 - 3.9e-42 142.2 24.9 7.8e-22 77.2 5.1 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF2208 PF09973.4 KUM65776.1 - 0.012 14.8 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) MFS_1 PF07690.11 KUM65777.1 - 1.9e-35 122.2 25.7 1.9e-35 122.2 17.8 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM65777.1 - 3.9e-13 48.7 11.3 3.9e-13 48.7 7.8 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter Myb_DNA-bind_6 PF13921.1 KUM65778.1 - 5.5e-05 23.1 0.0 0.00018 21.5 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KUM65778.1 - 0.00021 21.2 0.2 0.0008 19.4 0.1 2.0 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KUM65778.1 - 0.41 10.7 6.4 1.1 9.4 1.7 3.0 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain WSC PF01822.14 KUM65779.1 - 1.1e-16 60.4 11.3 2.7e-16 59.2 7.8 1.6 1 0 0 1 1 1 1 WSC domain F-box-like PF12937.2 KUM65781.1 - 6.1e-05 22.6 0.1 0.0002 20.9 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KUM65781.1 - 0.004 16.7 0.5 0.0097 15.5 0.0 1.9 2 0 0 2 2 2 1 F-box domain Ribosomal_S15 PF00312.17 KUM65783.1 - 1.3e-18 66.4 1.0 2e-18 65.9 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S15 LMP PF04778.7 KUM65783.1 - 0.0071 16.1 0.4 0.032 13.9 0.0 2.1 2 0 0 2 2 2 1 LMP repeated region Ribosomal_S2 PF00318.15 KUM65784.1 - 1.9e-42 144.9 0.0 8.4e-23 80.6 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 PseudoU_synth_1 PF01416.15 KUM65785.1 - 3.7e-27 94.8 0.0 5.5e-21 74.9 0.0 3.0 2 1 0 2 2 2 2 tRNA pseudouridine synthase PIG-H PF10181.4 KUM65786.1 - 1.1e-27 95.4 0.1 2.5e-27 94.3 0.0 1.6 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component XPG_I PF00867.13 KUM65788.1 - 6.2e-23 80.6 0.1 2.5e-22 78.7 0.0 2.1 3 0 0 3 3 3 1 XPG I-region XPG_N PF00752.12 KUM65788.1 - 1.5e-06 28.3 0.0 3.6e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain adh_short PF00106.20 KUM65791.1 - 3.3e-07 30.3 0.0 8.7e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM65791.1 - 0.0028 17.3 0.0 0.02 14.5 0.0 1.9 1 1 0 1 1 1 1 KR domain F-box PF00646.28 KUM65792.1 - 0.00063 19.3 0.0 0.0017 17.9 0.0 1.8 1 0 0 1 1 1 1 F-box domain Pribosyl_synth PF14572.1 KUM65793.1 - 9.2e-39 133.0 1.9 2.6e-33 115.3 0.4 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 KUM65793.1 - 9.9e-32 109.1 0.0 2.9e-31 107.6 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 KUM65793.1 - 4.7e-10 39.2 0.1 1.2e-09 37.9 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KUM65793.1 - 0.0062 15.7 0.2 0.01 15.0 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase MFS_1 PF07690.11 KUM65794.1 - 8.9e-14 50.9 19.7 1e-13 50.7 13.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM65794.1 - 1.2e-05 24.0 15.1 2e-05 23.3 10.5 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 KUM65794.1 - 0.094 12.5 0.0 0.094 12.5 0.0 2.6 3 1 1 4 4 4 0 MFS_1 like family MFS_2 PF13347.1 KUM65794.1 - 0.53 8.6 13.9 0.19 10.0 5.4 1.6 1 1 0 1 1 1 0 MFS/sugar transport protein DUF1361 PF07099.6 KUM65795.1 - 0.053 13.3 0.4 0.063 13.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1361) vATP-synt_AC39 PF01992.11 KUM65796.1 - 2.4e-107 358.9 0.0 2.8e-107 358.7 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit HAD_2 PF13419.1 KUM65797.1 - 2.7e-18 66.7 0.0 3.4e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KUM65797.1 - 1.1e-10 42.3 1.1 2.5e-06 28.0 0.1 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KUM65797.1 - 5.8e-09 36.3 0.0 9e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KUM65797.1 - 1.6e-08 34.1 0.0 3.8e-08 32.9 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 KUM65797.1 - 1.3e-05 25.0 0.1 0.0015 18.3 0.0 2.5 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Gp-FAR-1 PF05823.7 KUM65797.1 - 0.015 15.2 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Hydrolase_3 PF08282.7 KUM65797.1 - 0.083 12.4 0.1 0.72 9.3 0.0 2.2 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase RNA_pol_Rpb4 PF03874.11 KUM65798.1 - 2.7e-05 24.1 0.1 0.15 12.0 0.0 2.5 2 1 0 2 2 2 2 RNA polymerase Rpb4 Nop PF01798.13 KUM65799.1 - 2.5e-54 182.6 0.2 2.5e-54 182.6 0.2 1.9 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 KUM65799.1 - 1.8e-27 94.8 0.1 3.8e-27 93.8 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KUM65799.1 - 3.5e-23 81.5 2.2 3.5e-23 81.5 1.5 2.5 3 0 0 3 3 3 1 NOP5NT (NUC127) domain DUF760 PF05542.6 KUM65799.1 - 0.015 15.4 0.0 0.21 11.8 0.0 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF760) APH PF01636.18 KUM65801.1 - 1.9e-11 44.1 0.0 5.6e-11 42.6 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KUM65801.1 - 0.0032 16.1 0.0 1 7.9 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.9 KUM65801.1 - 0.049 12.5 0.0 0.89 8.4 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase PP-binding PF00550.20 KUM65802.1 - 7.4e-07 29.3 0.1 1.7e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 Phosphopantetheine attachment site Dimerisation PF08100.6 KUM65802.1 - 0.13 12.1 0.0 0.41 10.5 0.0 1.9 2 0 0 2 2 2 0 Dimerisation domain Aldo_ket_red PF00248.16 KUM65803.1 - 6.9e-45 153.0 0.0 8.4e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 KUM65804.1 - 2e-14 53.1 0.0 2.9e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family APH PF01636.18 KUM65805.1 - 5.8e-10 39.3 0.1 0.00021 21.1 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KUM65805.1 - 1e-09 37.7 0.0 2.9e-09 36.2 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KUM65805.1 - 4e-08 32.7 0.0 5.8e-08 32.1 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM65805.1 - 0.0044 16.1 0.0 0.0051 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 KUM65805.1 - 0.0055 16.2 0.0 0.0069 15.9 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KUM65805.1 - 0.0057 16.0 0.1 0.26 10.5 0.0 2.4 3 0 0 3 3 3 1 RIO1 family AP_endonuc_2 PF01261.19 KUM65805.1 - 0.029 13.6 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Phage_antitermQ PF06530.7 KUM65805.1 - 0.06 12.9 0.1 0.38 10.3 0.1 2.1 2 0 0 2 2 2 0 Phage antitermination protein Q Tox-MPTase3 PF15639.1 KUM65805.1 - 0.15 11.7 0.0 0.44 10.3 0.0 1.7 1 1 0 1 1 1 0 Metallopeptidase toxin 3 Zn_clus PF00172.13 KUM65806.1 - 1.5e-09 37.6 8.1 3.6e-09 36.3 5.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_Rpb1_5 PF04998.12 KUM65807.1 - 8.8e-87 290.8 0.3 1.5e-86 290.1 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 KUM65807.1 - 8.7e-86 288.2 0.1 1.4e-85 287.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 KUM65807.1 - 3e-67 225.7 0.0 6.9e-67 224.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KUM65807.1 - 4.2e-34 117.5 0.0 1.4e-32 112.6 0.0 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KUM65807.1 - 1.3e-27 95.7 0.1 3.5e-27 94.2 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Rpr2 PF04032.11 KUM65807.1 - 0.13 12.1 1.6 0.54 10.1 1.1 2.1 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain GTP_EFTU PF00009.22 KUM65808.1 - 7.9e-48 162.3 0.0 1.1e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 KUM65808.1 - 3.7e-39 132.9 4.2 6.3e-39 132.2 2.9 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 KUM65808.1 - 4.6e-18 64.8 0.0 9.8e-18 63.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.18 KUM65808.1 - 3.5e-05 23.7 0.0 8.5e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 KUM65808.1 - 0.00055 19.3 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 Ras family EFG_II PF14492.1 KUM65808.1 - 0.0006 19.6 0.0 0.0017 18.1 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KUM65808.1 - 0.0076 16.3 0.1 0.019 15.0 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.5 KUM65808.1 - 0.009 15.2 0.0 0.019 14.1 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit HORMA PF02301.13 KUM65809.1 - 8.7e-49 165.8 0.2 9.7e-49 165.6 0.1 1.0 1 0 0 1 1 1 1 HORMA domain Ribosomal_L13e PF01294.13 KUM65810.1 - 0.024 14.1 0.1 0.039 13.4 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L13e Ras PF00071.17 KUM65812.1 - 5.7e-12 45.3 0.0 2.4e-11 43.2 0.0 1.9 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KUM65812.1 - 2.4e-08 34.5 0.0 3.2e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 KUM65812.1 - 0.0017 18.4 0.0 0.068 13.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.15 KUM65812.1 - 0.0025 16.5 0.1 0.0061 15.2 0.0 1.6 2 0 0 2 2 2 1 G-protein alpha subunit NACHT PF05729.7 KUM65812.1 - 0.0077 15.8 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KUM65812.1 - 0.01 15.8 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 KUM65812.1 - 0.029 13.9 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arf PF00025.16 KUM65812.1 - 0.048 12.8 0.0 0.13 11.5 0.0 1.8 1 1 0 1 1 1 0 ADP-ribosylation factor family RNA_helicase PF00910.17 KUM65812.1 - 0.053 13.7 0.0 0.26 11.4 0.0 2.0 1 1 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 KUM65812.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KUM65812.1 - 0.1 12.9 0.1 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DEAD PF00270.24 KUM65813.1 - 1.9e-36 125.1 0.0 6.1e-36 123.4 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KUM65813.1 - 1.7e-21 75.4 0.0 3.5e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KUM65813.1 - 2.5e-19 68.9 0.0 8.3e-19 67.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KUM65813.1 - 0.0076 16.0 0.0 0.0076 16.0 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Pilt PF15453.1 KUM65813.1 - 0.2 11.3 10.6 0.28 10.8 7.4 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions UvrD-helicase PF00580.16 KUM65813.1 - 0.28 10.4 9.8 3 7.0 0.0 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain CTP_transf_1 PF01148.15 KUM65814.1 - 4.1e-18 65.9 5.6 7.9e-17 61.7 0.9 2.0 1 1 1 2 2 2 2 Cytidylyltransferase family Yip1 PF04893.12 KUM65815.1 - 0.0096 15.4 5.7 0.044 13.2 2.1 2.4 1 1 1 2 2 2 2 Yip1 domain TcdB_toxin_midC PF12255.3 KUM65815.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/C-terminal region zf-CCCH PF00642.19 KUM65816.1 - 0.00013 21.5 1.1 0.00022 20.8 0.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KUM65816.1 - 0.013 15.5 3.2 0.023 14.6 2.2 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type RapA_C PF12137.3 KUM65816.1 - 0.02 13.7 0.2 0.093 11.5 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase recycling family C-terminal Med26 PF08711.6 KUM65816.1 - 0.87 9.1 2.3 0.8 9.2 0.2 2.0 2 0 0 2 2 2 0 TFIIS helical bundle-like domain Sec1 PF00995.18 KUM65819.1 - 1.1e-155 519.4 0.0 1.3e-155 519.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF1199 PF06712.6 KUM65823.1 - 0.12 12.1 0.0 13 5.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1199) Band_7 PF01145.20 KUM65824.1 - 9.1e-25 87.5 1.8 1.4e-24 87.0 1.2 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family COG5 PF10392.4 KUM65826.1 - 0.051 13.5 0.0 0.18 11.8 0.0 1.9 1 0 0 1 1 1 0 Golgi transport complex subunit 5 SKG6 PF08693.5 KUM65827.1 - 9.3e-05 21.6 0.2 0.00029 20.0 0.2 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Lamp PF01299.12 KUM65827.1 - 1.7 7.7 20.8 0.86 8.6 0.1 3.0 2 1 1 3 3 3 0 Lysosome-associated membrane glycoprotein (Lamp) Methyltransf_2 PF00891.13 KUM65828.1 - 3.7e-30 104.8 0.0 5.8e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Bac_luciferase PF00296.15 KUM65830.1 - 1.5e-61 208.1 0.6 2.3e-61 207.5 0.4 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Pyr_redox_3 PF13738.1 KUM65831.1 - 2.1e-21 76.9 0.0 4e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KUM65831.1 - 1.5e-16 59.7 0.1 1.7e-13 49.6 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KUM65831.1 - 1.2e-10 41.2 0.0 4.4e-10 39.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KUM65831.1 - 0.0003 19.8 0.0 0.00054 18.9 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KUM65831.1 - 0.0035 17.2 0.0 0.011 15.6 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM65831.1 - 0.0038 17.0 0.2 0.034 13.9 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 KUM65831.1 - 0.016 14.3 0.0 0.092 11.8 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.17 KUM65831.1 - 0.48 9.2 0.9 16 4.2 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Acetyltransf_7 PF13508.1 KUM65832.1 - 1.8e-07 31.1 0.0 3.1e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KUM65832.1 - 2.9e-07 30.4 0.0 5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KUM65832.1 - 0.00024 21.2 0.0 0.00038 20.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KUM65832.1 - 0.0011 18.6 0.0 0.0027 17.4 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Actin PF00022.14 KUM65833.1 - 9.5e-22 76.9 0.0 3.2e-20 71.9 0.0 2.7 2 1 0 2 2 2 1 Actin CENP-L PF13092.1 KUM65834.1 - 1.7e-55 187.2 0.1 2.3e-55 186.8 0.0 1.2 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 HNH_2 PF13391.1 KUM65835.1 - 0.0023 17.6 0.0 0.0064 16.2 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease KR PF08659.5 KUM65836.1 - 5.5e-23 81.5 0.0 1.2e-22 80.4 0.0 1.6 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.21 KUM65836.1 - 4.7e-19 68.2 0.1 1.6e-18 66.5 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.20 KUM65836.1 - 8.3e-18 64.8 0.2 3.1e-17 62.9 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.1 KUM65836.1 - 1.2e-10 42.3 0.0 8.6e-10 39.6 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM65836.1 - 2e-05 24.2 0.0 4.5e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 KUM65836.1 - 0.028 14.4 0.3 7.9 6.4 0.0 2.5 2 0 0 2 2 2 0 NADH(P)-binding ELFV_dehydrog PF00208.16 KUM65836.1 - 0.029 13.9 0.1 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase PALP PF00291.20 KUM65836.1 - 0.045 12.9 0.2 0.15 11.2 0.1 1.8 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme NmrA PF05368.8 KUM65836.1 - 0.06 12.5 0.0 2.5 7.3 0.0 2.3 2 0 0 2 2 2 0 NmrA-like family 2H-phosphodiest PF08975.5 KUM65836.1 - 0.13 12.0 0.0 0.82 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1868) PS-DH PF14765.1 KUM65837.1 - 4.4e-37 127.8 0.0 6e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KUM65837.1 - 1.8e-17 63.6 0.0 4.7e-16 59.0 0.0 2.5 2 1 0 2 2 2 1 Acyl transferase domain Methyltransf_12 PF08242.7 KUM65837.1 - 3.2e-12 46.7 0.0 1.1e-11 45.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM65837.1 - 7.3e-11 42.0 0.0 2.5e-10 40.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM65837.1 - 4.9e-08 33.3 0.0 1.6e-07 31.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM65837.1 - 7.8e-08 32.0 0.0 3.3e-07 30.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM65837.1 - 1.4e-07 32.0 0.0 1.3e-06 28.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KUM65837.1 - 6.2e-05 22.2 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KUM65837.1 - 0.022 14.1 0.0 0.062 12.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.14 KUM65837.1 - 0.042 13.3 0.0 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ketoacyl-synt PF00109.21 KUM65838.1 - 1.2e-60 205.1 0.1 2.1e-60 204.3 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KUM65838.1 - 1.9e-40 137.3 0.6 1e-39 135.0 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 KUM65838.1 - 1.4e-22 80.4 0.0 1.8e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Thiolase_N PF00108.18 KUM65838.1 - 0.00096 18.2 0.3 0.002 17.1 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain HAD PF12710.2 KUM65839.1 - 1.8e-21 77.2 0.0 3.4e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KUM65839.1 - 3e-21 76.8 0.0 3e-20 73.5 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KUM65839.1 - 4.3e-21 75.0 0.1 1.2e-20 73.5 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KUM65839.1 - 0.00023 21.0 0.0 0.0019 18.0 0.0 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KUM65839.1 - 0.0054 16.3 0.1 0.016 14.7 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Wound_ind PF08186.6 KUM65840.1 - 0.034 14.0 0.1 0.06 13.2 0.1 1.3 1 0 0 1 1 1 0 Wound-inducible basic protein family PKD_channel PF08016.7 KUM65841.1 - 2.1e-06 26.4 21.1 6.7e-05 21.4 14.7 2.5 1 1 0 1 1 1 1 Polycystin cation channel EIF_2_alpha PF07541.7 KUM65842.1 - 5.7e-38 129.1 0.0 1.5e-37 127.7 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 KUM65842.1 - 2.1e-12 46.9 0.6 4.6e-12 45.8 0.4 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Sulfate_transp PF00916.15 KUM65843.1 - 1.7e-46 158.4 6.9 3.7e-46 157.3 4.8 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KUM65843.1 - 2.8e-27 94.2 5.4 1.4e-26 91.9 3.8 2.3 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KUM65843.1 - 5.1e-15 54.9 0.0 1e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 KUM65843.1 - 0.00015 21.6 0.0 0.00077 19.4 0.0 2.2 2 1 0 2 2 2 1 STAS domain FF PF01846.14 KUM65844.1 - 6.7e-13 48.3 6.0 1.2e-09 37.9 0.1 3.4 3 0 0 3 3 3 2 FF domain Epiglycanin_TR PF05647.6 KUM65845.1 - 0.038 13.7 1.9 0.24 11.2 0.1 2.4 2 0 0 2 2 2 0 Tandem-repeating region of mucin, epiglycanin-like V_ATPase_I PF01496.14 KUM65845.1 - 2.2 6.0 4.4 2.8 5.6 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GFO_IDH_MocA PF01408.17 KUM65847.1 - 4.8e-20 72.2 0.0 3.6e-18 66.1 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KUM65847.1 - 3.9e-07 29.8 0.0 7.3e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 KUM65847.1 - 0.0066 16.8 0.0 0.022 15.1 0.0 1.9 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain Gp_dh_N PF00044.19 KUM65847.1 - 0.008 16.1 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Sugar_tr PF00083.19 KUM65848.1 - 6.5e-72 242.5 15.9 2.7e-59 200.9 1.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KUM65848.1 - 9.2e-29 100.2 15.4 1.3e-28 99.7 10.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_2 PF04550.7 KUM65848.1 - 0.19 11.8 3.9 0.23 11.5 0.4 2.5 2 0 0 2 2 2 0 Phage holin family 2 NAD_binding_10 PF13460.1 KUM65849.1 - 1e-12 48.4 0.0 1.4e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KUM65849.1 - 5.1e-06 26.0 0.0 2.1e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KUM65849.1 - 0.00011 22.4 0.0 0.00058 20.1 0.0 1.9 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KUM65849.1 - 0.00018 20.5 0.1 0.36 9.7 0.0 2.3 1 1 0 2 2 2 2 Male sterility protein NmrA PF05368.8 KUM65849.1 - 0.0023 17.2 0.0 0.0038 16.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 KUM65849.1 - 0.0054 15.4 0.0 0.0071 15.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family HIM1 PF08732.5 KUM65849.1 - 0.029 12.8 0.0 0.04 12.3 0.0 1.1 1 0 0 1 1 1 0 HIM1 TraC PF07820.7 KUM65849.1 - 0.032 14.4 0.0 0.075 13.2 0.0 1.6 1 0 0 1 1 1 0 TraC-like protein Ldh_1_N PF00056.18 KUM65849.1 - 0.072 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DUF4094 PF13334.1 KUM65851.1 - 0.017 15.5 0.4 0.021 15.1 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Not3 PF04065.10 KUM65851.1 - 0.1 11.8 1.7 0.14 11.3 1.1 1.3 1 1 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Proteasome PF00227.21 KUM65853.1 - 2.5e-61 206.2 0.2 3e-61 206.0 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KUM65853.1 - 3.2e-14 51.9 0.4 7.1e-14 50.8 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Cellulase PF00150.13 KUM65854.1 - 2.4e-14 53.2 3.5 2.4e-14 53.2 2.4 1.8 1 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) EphA2_TM PF14575.1 KUM65854.1 - 0.18 12.2 0.8 0.42 11.0 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF1777 PF08648.7 KUM65854.1 - 0.51 10.0 30.0 0.98 9.1 20.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) TPP_enzyme_N PF02776.13 KUM65856.1 - 5.5e-41 139.9 0.1 6.1e-40 136.5 0.1 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KUM65856.1 - 3e-22 78.8 0.1 3.5e-21 75.3 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KUM65856.1 - 7.4e-14 51.6 0.0 1.9e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain XFP_N PF09364.5 KUM65856.1 - 0.21 10.0 0.6 0.34 9.4 0.4 1.2 1 0 0 1 1 1 0 XFP N-terminal domain HATPase_c PF02518.21 KUM65857.1 - 2.8e-17 62.4 0.1 8.5e-17 60.8 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KUM65857.1 - 1.1e-13 51.1 0.0 2.9e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KUM65857.1 - 2.5e-13 49.7 0.6 6e-13 48.5 0.4 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PHY PF00360.15 KUM65857.1 - 2.9e-06 26.5 0.0 9.2e-06 24.9 0.0 1.8 2 0 0 2 2 2 1 Phytochrome region GAF PF01590.21 KUM65857.1 - 0.00054 20.1 0.0 0.0017 18.5 0.0 1.9 1 0 0 1 1 1 1 GAF domain PAS_2 PF08446.6 KUM65857.1 - 0.0022 18.4 0.0 0.0069 16.8 0.0 1.8 1 0 0 1 1 1 1 PAS fold SNF2_N PF00176.18 KUM65858.1 - 2.3e-74 249.8 0.0 4.1e-74 249.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KUM65858.1 - 2.7e-11 43.1 0.0 1.1e-10 41.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD_2 PF06733.10 KUM65858.1 - 0.0072 15.7 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 DEAD_2 SIR2 PF02146.12 KUM65859.1 - 9.5e-38 129.6 0.0 5.6e-37 127.1 0.0 1.9 1 1 0 1 1 1 1 Sir2 family DUF4231 PF14015.1 KUM65859.1 - 0.055 13.4 0.1 0.09 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Ribosomal_L6 PF00347.18 KUM65861.1 - 1.9e-23 82.7 0.0 1.3e-11 44.8 0.0 3.1 3 0 0 3 3 3 2 Ribosomal protein L6 Inositol_P PF00459.20 KUM65862.1 - 2.8e-50 171.1 1.5 6e-50 170.0 1.0 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family MFS_1 PF07690.11 KUM65863.1 - 1e-41 142.8 45.9 1e-41 142.8 31.8 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM65863.1 - 7.6e-15 54.4 14.6 7.6e-15 54.4 10.1 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter DUF2140 PF09911.4 KUM65863.1 - 0.19 10.8 0.1 0.41 9.8 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) CorA PF01544.13 KUM65863.1 - 7.1 5.5 7.0 0.44 9.5 0.7 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Tannase PF07519.6 KUM65864.1 - 1.2e-119 400.1 0.8 1.8e-119 399.5 0.6 1.3 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 KUM65864.1 - 1.4e-06 28.1 0.0 0.0038 17.0 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KUM65864.1 - 0.00018 21.4 0.0 0.00058 19.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KUM65864.1 - 0.0022 17.2 0.3 0.033 13.4 0.2 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KUM65864.1 - 0.0087 15.6 0.0 0.013 15.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.11 KUM65866.1 - 2.7e-17 62.5 45.5 2.7e-17 62.5 31.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily VHS PF00790.14 KUM65867.1 - 7.8e-25 87.1 0.0 1.6e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 KUM65867.1 - 1.8e-08 34.2 0.2 3.9e-08 33.1 0.2 1.5 1 0 0 1 1 1 1 GAT domain ENTH PF01417.15 KUM65867.1 - 0.0012 18.7 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 ENTH domain Dexa_ind PF15198.1 KUM65867.1 - 0.053 13.4 0.2 0.52 10.2 0.1 2.2 2 0 0 2 2 2 0 Dexamethasone-induced Abhydrolase_6 PF12697.2 KUM65869.1 - 1.8e-09 37.8 0.0 2.4e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM65869.1 - 3.6e-08 33.2 0.0 5.2e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KUM65869.1 - 7.7e-05 22.3 0.1 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 KUM65869.1 - 0.00034 20.2 0.2 0.82 9.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF676 PF05057.9 KUM65869.1 - 0.00063 19.0 0.0 0.00085 18.6 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF818 PF05677.7 KUM65869.1 - 0.0023 16.7 0.0 0.0031 16.2 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.11 KUM65869.1 - 0.007 15.8 0.0 2.2 7.6 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase fn3 PF00041.16 KUM65869.1 - 0.048 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type III domain Cutinase PF01083.17 KUM65869.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Cutinase DUF2305 PF10230.4 KUM65869.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Flavoprotein PF02441.14 KUM65870.1 - 3.7e-10 39.5 0.0 6.6e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Flavoprotein DUF1391 PF07151.7 KUM65870.1 - 0.05 13.1 0.3 0.13 11.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1391) FAD_binding_1 PF00667.15 KUM65871.1 - 3.1e-60 203.3 0.0 5.5e-60 202.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KUM65871.1 - 3.7e-11 43.5 0.0 1.1e-10 42.0 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 KUM65871.1 - 6.6e-07 29.3 0.8 1.5e-06 28.2 0.2 1.8 2 0 0 2 2 2 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 KUM65871.1 - 0.0016 18.4 0.1 0.0068 16.3 0.1 2.1 1 0 0 1 1 1 1 Transketolase, C-terminal domain FtsJ PF01728.14 KUM65872.1 - 2.7e-62 209.9 0.0 3.5e-62 209.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Aldo_ket_red PF00248.16 KUM65873.1 - 4.2e-54 183.2 0.0 5.1e-54 183.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Acyl-CoA_dh_1 PF00441.19 KUM65874.1 - 4.7e-33 114.3 0.5 8.8e-33 113.5 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KUM65874.1 - 2.1e-19 68.7 0.5 3.7e-19 67.9 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KUM65874.1 - 4.5e-14 52.9 0.2 2.4e-13 50.6 0.0 2.4 3 1 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KUM65874.1 - 1.1e-06 28.9 1.3 1.2e-06 28.7 0.3 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DEAD PF00270.24 KUM65875.1 - 6.6e-44 149.3 0.2 1.4e-43 148.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM65875.1 - 1.9e-22 78.8 0.1 7.9e-22 76.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KUM65875.1 - 0.0074 15.1 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 KUM65875.1 - 0.015 15.4 0.3 0.052 13.6 0.2 2.0 1 1 0 1 1 1 0 AAA domain Neur_chan_memb PF02932.11 KUM65875.1 - 1.6 8.5 3.1 1.5 8.6 0.9 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Sec62 PF03839.11 KUM65875.1 - 7.3 5.9 12.7 17 4.7 8.8 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 DUF1688 PF07958.6 KUM65876.1 - 7.1e-167 555.1 0.0 8e-167 555.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) zf-HYPF PF07503.7 KUM65877.1 - 0.035 13.5 0.3 0.082 12.3 0.2 1.6 1 0 0 1 1 1 0 HypF finger FMO-like PF00743.14 KUM65878.1 - 2.7e-25 88.5 0.0 2.9e-18 65.3 0.0 3.3 3 1 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KUM65878.1 - 2.9e-22 79.7 0.0 7.6e-22 78.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KUM65878.1 - 1.7e-11 44.4 0.0 2.4e-10 40.6 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KUM65878.1 - 2.6e-09 37.3 0.3 0.0021 18.4 0.1 3.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KUM65878.1 - 6.1e-09 35.3 0.2 0.0012 18.0 0.1 3.2 3 0 0 3 3 3 2 FAD binding domain K_oxygenase PF13434.1 KUM65878.1 - 2.9e-08 33.0 0.1 1.1e-06 27.8 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KUM65878.1 - 6.7e-07 29.2 0.0 0.00071 19.5 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KUM65878.1 - 4.3e-05 22.7 0.0 0.12 11.4 0.0 2.3 2 0 0 2 2 2 2 Thi4 family FAD_oxidored PF12831.2 KUM65878.1 - 8.8e-05 21.7 0.0 0.069 12.2 0.0 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase DAO PF01266.19 KUM65878.1 - 0.00011 21.2 0.6 0.18 10.6 0.2 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 KUM65878.1 - 0.00012 21.2 0.0 0.1 11.7 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 KUM65878.1 - 0.00029 20.6 1.8 4.2 7.1 2.0 3.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.17 KUM65878.1 - 0.0016 17.4 0.0 0.12 11.2 0.0 2.5 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 KUM65878.1 - 0.0083 14.6 0.1 0.81 8.0 0.0 2.8 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_10 PF13460.1 KUM65878.1 - 0.047 13.7 0.0 7.6 6.4 0.0 2.5 2 0 0 2 2 2 0 NADH(P)-binding Lycopene_cycl PF05834.7 KUM65878.1 - 0.077 11.9 0.0 0.33 9.8 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 KUM65878.1 - 0.099 11.4 0.1 1.3 7.7 0.1 2.4 2 1 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.15 KUM65878.1 - 0.16 12.1 0.0 22 5.1 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 KUM65881.1 - 3.8e-25 88.5 0.1 5e-25 88.1 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KUM65881.1 - 0.0023 17.8 0.0 0.079 12.8 0.5 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KUM65881.1 - 0.0027 18.0 2.5 0.0046 17.3 1.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KUM65881.1 - 0.02 14.9 0.1 0.047 13.7 0.1 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KUM65881.1 - 0.025 13.4 0.0 0.038 12.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 KUM65881.1 - 0.031 13.3 0.4 0.054 12.5 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.16 KUM65881.1 - 0.1 12.3 0.2 0.64 9.8 0.2 2.2 2 0 0 2 2 2 0 ThiF family 3HCDH_N PF02737.13 KUM65881.1 - 0.11 12.1 0.5 0.18 11.4 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 KUM65881.1 - 0.4 10.7 2.2 0.41 10.6 0.3 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain PTR2 PF00854.16 KUM65882.1 - 1.1e-47 162.5 10.5 5.7e-31 107.6 0.7 2.3 2 0 0 2 2 2 2 POT family CcmH PF03918.9 KUM65882.1 - 0.37 9.7 2.5 17 4.3 0.1 3.2 2 1 1 3 3 3 0 Cytochrome C biogenesis protein Abhydrolase_3 PF07859.8 KUM65883.1 - 1.8e-53 181.2 0.0 2.3e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KUM65883.1 - 2e-05 23.5 0.6 8.3e-05 21.4 0.4 1.8 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 KUM65883.1 - 6.3e-05 22.2 0.0 0.0041 16.3 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KUM65883.1 - 0.0034 17.1 0.0 0.0048 16.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 KUM65883.1 - 0.024 13.8 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase DLH PF01738.13 KUM65883.1 - 0.17 11.1 0.0 1.6 7.9 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family Gpi16 PF04113.9 KUM65884.1 - 3.9e-254 843.8 0.0 4.6e-254 843.6 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Put_DNA-bind_N PF06971.8 KUM65885.1 - 0.075 12.8 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus LUC7 PF03194.10 KUM65886.1 - 3.5e-37 128.3 0.9 3.9e-37 128.1 0.6 1.0 1 0 0 1 1 1 1 LUC7 N_terminus MCPsignal PF00015.16 KUM65886.1 - 0.039 13.4 0.1 0.051 13.1 0.1 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4200 PF13863.1 KUM65886.1 - 0.072 13.0 0.2 2.5 8.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DegS PF05384.6 KUM65886.1 - 0.13 11.4 1.8 1.5 8.0 0.1 2.2 1 1 1 2 2 2 0 Sensor protein DegS Cep57_MT_bd PF06657.8 KUM65886.1 - 0.17 11.8 2.6 7.1 6.6 0.1 3.0 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Prefoldin PF02996.12 KUM65886.1 - 0.21 11.2 1.4 1.4 8.5 0.2 2.2 2 0 0 2 2 2 0 Prefoldin subunit GRP PF07172.6 KUM65886.1 - 1.3 9.5 13.6 1.8 9.0 8.0 2.0 2 0 0 2 2 2 0 Glycine rich protein family TFIIS_M PF07500.9 KUM65888.1 - 2.9e-23 82.1 0.7 2.9e-23 82.1 0.5 1.6 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 KUM65888.1 - 3.5e-19 69.4 0.0 7.3e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 KUM65888.1 - 2.2e-10 40.0 12.5 3.9e-10 39.2 8.7 1.4 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.1 KUM65888.1 - 0.008 16.3 0.3 0.029 14.6 0.2 2.0 1 0 0 1 1 1 1 PHD domain of transcriptional enhancer, Asx PHD_2 PF13831.1 KUM65888.1 - 0.047 12.9 6.2 0.077 12.3 4.3 1.4 1 0 0 1 1 1 0 PHD-finger Terminase_GpA PF05876.7 KUM65888.1 - 1 7.6 5.6 1.6 7.0 3.9 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Menin PF05053.8 KUM65888.1 - 2.5 6.1 7.0 4.3 5.3 4.9 1.3 1 0 0 1 1 1 0 Menin APG12 PF04110.8 KUM65889.1 - 2.8e-29 101.1 0.0 5.6e-29 100.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 KUM65889.1 - 0.0042 17.0 0.0 0.0055 16.6 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Pantoate_transf PF02548.10 KUM65890.1 - 3.3e-106 354.1 1.0 4e-106 353.9 0.7 1.1 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 KUM65890.1 - 4.7e-08 32.5 0.5 1.2e-07 31.2 0.4 1.8 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Ribosomal_S5 PF00333.15 KUM65890.1 - 0.11 12.2 0.9 0.75 9.5 0.1 2.7 2 1 0 2 2 2 0 Ribosomal protein S5, N-terminal domain UQ_con PF00179.21 KUM65891.1 - 1.3e-31 108.8 0.2 1.5e-31 108.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ank_2 PF12796.2 KUM65892.1 - 8e-50 167.1 2.6 7.8e-15 54.9 0.0 8.5 5 2 1 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KUM65892.1 - 8.7e-34 115.2 4.7 7.1e-06 26.3 0.0 12.7 11 2 2 13 13 13 9 Ankyrin repeats (many copies) Ank PF00023.25 KUM65892.1 - 8.3e-33 110.5 15.9 5.7e-06 25.8 0.0 13.2 15 0 0 15 15 15 6 Ankyrin repeat Ank_5 PF13857.1 KUM65892.1 - 2.9e-32 109.9 6.9 0.00016 21.7 0.0 11.6 11 1 1 12 12 12 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM65892.1 - 8.2e-27 90.5 6.3 0.007 16.5 0.0 12.1 13 0 0 13 13 13 6 Ankyrin repeat Pyridox_ox_2 PF12900.2 KUM65893.1 - 6.4e-37 126.5 0.0 8.2e-37 126.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Peptidase_M24 PF00557.19 KUM65894.1 - 1.1e-50 172.1 0.0 1.6e-50 171.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KUM65894.1 - 6e-35 119.5 0.0 1.1e-34 118.7 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Tht1 PF04163.7 KUM65895.1 - 4.1e-06 25.4 0.7 4.1e-06 25.4 0.5 2.3 2 1 0 3 3 3 1 Tht1-like nuclear fusion protein Baculo_PEP_C PF04513.7 KUM65895.1 - 0.0048 16.7 5.8 0.0048 16.7 4.0 2.5 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.6 KUM65895.1 - 1.9 8.3 9.5 2.8 7.8 0.6 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) CDC37_N PF03234.9 KUM65895.1 - 8.8 6.6 14.7 15 5.8 3.2 3.0 3 0 0 3 3 3 0 Cdc37 N terminal kinase binding DUF2011 PF09428.5 KUM65897.1 - 4.3e-44 149.5 4.9 6.2e-44 149.0 3.4 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) DUF2058 PF09831.4 KUM65897.1 - 5.1 6.9 11.2 12 5.7 7.8 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) LAMTOR PF15454.1 KUM65898.1 - 4.4e-24 84.5 0.1 7.1e-24 83.8 0.1 1.3 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF4045 PF13254.1 KUM65898.1 - 0.0059 15.9 2.8 0.0077 15.5 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4045) Dfp1_Him1_M PF08630.5 KUM65900.1 - 3e-41 140.1 0.0 7.2e-41 138.8 0.0 1.7 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 KUM65900.1 - 2.5e-24 84.6 0.3 5.6e-24 83.5 0.2 1.6 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.2 KUM65900.1 - 0.0072 16.1 0.0 0.02 14.7 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KUM65900.1 - 0.029 14.5 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DUF2360 PF10152.4 KUM65901.1 - 2.5 8.3 7.5 1.6 9.0 1.3 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) MFS_1 PF07690.11 KUM65903.1 - 6.9e-39 133.5 52.3 6.1e-38 130.4 36.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KUM65903.1 - 1.8 6.8 35.1 0.25 9.6 11.8 3.4 1 1 0 2 2 2 0 MFS/sugar transport protein Terpene_synth_C PF03936.11 KUM65904.1 - 8e-06 25.2 0.3 1.3e-05 24.6 0.2 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Pyridox_oxase_2 PF12766.2 KUM65905.1 - 1.5e-28 99.0 0.0 2.6e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase MFS_1 PF07690.11 KUM65907.1 - 1.3e-30 106.3 28.0 1.6e-30 106.0 19.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily GMC_oxred_N PF00732.14 KUM65908.1 - 9.7e-67 225.1 0.2 1.2e-66 224.8 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KUM65908.1 - 2.9e-35 121.6 0.0 5.4e-35 120.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.1 KUM65908.1 - 5.1e-07 29.9 0.3 0.036 14.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KUM65908.1 - 4.3e-06 25.8 0.1 0.013 14.4 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 KUM65908.1 - 1.7e-05 24.7 0.9 0.0017 18.2 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM65908.1 - 5.6e-05 23.0 0.1 0.00021 21.2 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KUM65908.1 - 7e-05 21.8 0.6 0.0042 16.0 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KUM65908.1 - 0.00021 19.8 0.4 0.0094 14.4 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 KUM65908.1 - 0.0009 19.0 2.1 0.073 12.8 0.0 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KUM65908.1 - 0.0014 17.6 0.0 0.0029 16.5 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KUM65908.1 - 0.0036 16.4 0.7 0.016 14.2 0.1 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 KUM65908.1 - 0.024 15.0 0.2 0.26 11.7 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase YmdB PF13277.1 KUM65908.1 - 0.076 12.0 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 YmdB-like protein Aminotran_1_2 PF00155.16 KUM65909.1 - 1.3e-10 40.7 0.0 3.3e-10 39.4 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II zf-C2H2_4 PF13894.1 KUM65911.1 - 4 7.9 48.2 0.2 12.0 0.6 7.4 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KUM65912.1 - 0.023 15.0 25.8 0.34 11.3 1.0 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type ORC3_N PF07034.6 KUM65913.1 - 5.9e-34 117.5 0.0 1e-32 113.4 0.0 2.3 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus PPR_2 PF13041.1 KUM65914.1 - 5.9e-07 29.3 0.1 2.6 8.0 0.0 5.3 5 1 1 6 6 6 3 PPR repeat family PPR_3 PF13812.1 KUM65914.1 - 2.3e-05 24.3 0.8 0.57 10.6 0.0 6.0 8 0 0 8 8 8 2 Pentatricopeptide repeat domain TPR_14 PF13428.1 KUM65914.1 - 0.19 12.4 5.7 3 8.7 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Nop14 PF04147.7 KUM65915.1 - 2.9e-279 928.6 35.3 3.4e-279 928.4 24.5 1.0 1 0 0 1 1 1 1 Nop14-like family HEAT_2 PF13646.1 KUM65916.1 - 0.0054 16.9 1.0 0.019 15.2 0.7 2.0 1 1 0 1 1 1 1 HEAT repeats PPR_1 PF12854.2 KUM65916.1 - 0.25 10.8 0.9 0.47 9.9 0.6 1.4 1 0 0 1 1 1 0 PPR repeat Sec66 PF09802.4 KUM65919.1 - 3.7e-82 274.3 0.4 4.4e-82 274.0 0.3 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Duffy_binding PF05424.6 KUM65919.1 - 0.081 12.7 9.9 0.31 10.8 6.8 1.9 1 1 0 1 1 1 0 Duffy binding domain AAA PF00004.24 KUM65920.1 - 4.5e-49 166.0 0.0 8.9e-42 142.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KUM65920.1 - 6.5e-08 32.1 0.0 2.1e-05 24.0 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 KUM65920.1 - 2.8e-06 27.3 0.0 9.2e-06 25.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KUM65920.1 - 2.8e-06 27.4 1.1 1.8e-05 24.8 0.0 2.8 3 0 0 3 3 2 1 AAA ATPase domain AAA_5 PF07728.9 KUM65920.1 - 4.2e-05 23.3 0.0 0.0012 18.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KUM65920.1 - 7.6e-05 22.8 0.0 0.0031 17.6 0.0 3.1 2 1 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 KUM65920.1 - 0.0002 21.4 0.0 0.13 12.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Bromodomain PF00439.20 KUM65920.1 - 0.00022 21.0 0.0 0.00066 19.5 0.0 1.7 1 0 0 1 1 1 1 Bromodomain AAA_14 PF13173.1 KUM65920.1 - 0.0011 18.9 0.0 0.016 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KUM65920.1 - 0.0022 18.1 0.0 0.0065 16.6 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.1 KUM65920.1 - 0.0032 17.0 0.1 0.0098 15.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KUM65920.1 - 0.0042 16.8 0.0 0.048 13.4 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 KUM65920.1 - 0.0046 17.7 0.0 0.033 15.0 0.0 2.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KUM65920.1 - 0.0069 15.8 0.0 0.025 13.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KUM65920.1 - 0.011 14.9 0.1 0.13 11.3 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 KUM65920.1 - 0.013 14.1 0.0 0.021 13.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_33 PF13671.1 KUM65920.1 - 0.015 15.2 0.0 0.047 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KUM65920.1 - 0.02 13.9 0.0 0.06 12.3 0.0 1.8 2 0 0 2 2 1 0 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 KUM65920.1 - 0.033 13.6 0.0 0.98 8.8 0.0 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KUM65920.1 - 0.051 12.4 0.0 0.2 10.4 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 KUM65920.1 - 0.086 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KUM65920.1 - 0.094 12.3 0.0 0.9 9.1 0.0 2.4 2 1 0 2 2 2 0 NACHT domain Zot PF05707.7 KUM65920.1 - 0.12 11.8 0.0 0.39 10.1 0.0 1.9 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) PhoH PF02562.11 KUM65920.1 - 0.15 11.2 0.0 0.45 9.7 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein Torsin PF06309.6 KUM65920.1 - 0.22 11.4 0.0 0.49 10.2 0.0 1.5 1 0 0 1 1 1 0 Torsin Pro_CA PF00484.14 KUM65921.1 - 4e-49 166.5 0.0 5.8e-49 166.0 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase GDA1_CD39 PF01150.12 KUM65922.1 - 1.4e-104 350.0 0.0 1.9e-104 349.6 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ammonium_transp PF00909.16 KUM65923.1 - 2.3e-112 375.3 25.5 2.7e-112 375.1 17.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF1691 PF07950.6 KUM65923.1 - 0.019 14.8 3.2 0.22 11.4 0.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1691) LRR_9 PF14580.1 KUM65925.1 - 1.9e-54 183.8 0.0 3e-54 183.2 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 KUM65925.1 - 1e-10 40.9 5.8 0.00039 19.9 0.0 3.6 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KUM65925.1 - 9.1e-08 31.7 7.8 1.2e-05 24.9 0.7 3.3 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 KUM65925.1 - 0.00076 19.1 6.6 9.4 6.7 0.0 5.2 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 KUM65925.1 - 0.023 14.8 5.6 16 6.2 0.0 4.7 4 0 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 KUM65925.1 - 0.15 12.1 5.6 5.6 7.3 0.1 4.5 4 1 0 4 4 4 0 Leucine Rich repeat FAD_binding_4 PF01565.18 KUM65926.1 - 2.9e-20 72.1 0.6 4.9e-20 71.4 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain DUF3579 PF12112.3 KUM65927.1 - 0.15 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3579) HET PF06985.6 KUM65928.1 - 3.8e-09 36.8 0.0 1.7e-06 28.2 0.0 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Peptidase_S41 PF03572.13 KUM65930.1 - 2.1e-07 30.4 0.0 2.2e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S41 SNF2_N PF00176.18 KUM65932.1 - 1.2e-46 158.8 0.0 1.9e-46 158.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KUM65932.1 - 7.1e-09 35.4 0.0 1.6e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 KUM65932.1 - 1.5e-06 27.8 7.3 2.7e-06 27.0 5.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KUM65932.1 - 3.3e-05 23.8 2.0 8e-05 22.5 1.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KUM65932.1 - 7.7e-05 22.2 4.8 0.00013 21.5 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KUM65932.1 - 0.0014 18.3 6.6 0.0028 17.4 4.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KUM65932.1 - 0.11 12.1 6.0 0.28 10.8 4.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KUM65932.1 - 0.48 10.1 3.6 1.3 8.8 2.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 KUM65932.1 - 0.57 9.8 6.5 1.2 8.7 4.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.2 KUM65932.1 - 1.5 8.7 6.6 14 5.5 4.7 2.2 1 1 1 2 2 2 0 Double zinc ribbon DUF221 PF02714.10 KUM65933.1 - 7.2e-110 366.8 20.2 7.2e-110 366.8 14.0 2.6 3 0 0 3 3 3 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 KUM65933.1 - 3.2e-43 146.9 3.2 3.2e-43 146.9 2.2 2.6 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KUM65933.1 - 8.5e-33 112.1 0.3 3.6e-32 110.1 0.1 2.0 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 KUM65933.1 - 7e-22 77.7 0.3 1.2e-21 77.0 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) MCM PF00493.18 KUM65935.1 - 6.6e-131 436.0 0.1 1.1e-130 435.3 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KUM65935.1 - 1.2e-15 58.0 0.8 4e-15 56.3 0.0 2.4 3 1 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 KUM65935.1 - 4.7e-05 22.6 0.0 0.00019 20.6 0.0 1.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KUM65935.1 - 0.0044 16.7 0.0 0.012 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KUM65935.1 - 0.0065 16.0 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KUM65935.1 - 0.0094 15.4 0.0 0.025 14.0 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain E1-E2_ATPase PF00122.15 KUM65936.1 - 3.5e-45 153.8 6.3 7.1e-45 152.8 4.3 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KUM65936.1 - 5.9e-21 75.8 0.7 1.4e-20 74.6 0.0 2.0 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KUM65936.1 - 8.2e-12 45.6 0.0 2.3e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KUM65936.1 - 2.5e-05 24.0 1.2 0.0015 18.1 0.3 2.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HMA PF00403.21 KUM65936.1 - 3.3e-05 23.9 0.3 0.00013 22.0 0.0 2.1 2 0 0 2 2 2 1 Heavy-metal-associated domain SNF2_N PF00176.18 KUM65939.1 - 1e-37 129.5 0.0 4.1e-36 124.3 0.0 2.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KUM65939.1 - 8.9e-07 28.6 0.0 2.2e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 KUM65939.1 - 0.0023 17.5 6.7 0.0046 16.5 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KUM65939.1 - 0.027 14.4 9.4 0.076 13.0 6.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KUM65939.1 - 0.05 13.2 6.5 0.35 10.5 4.7 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KUM65939.1 - 0.12 12.1 9.1 0.32 10.7 6.3 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 KUM65939.1 - 1.7 8.5 8.9 4.8 7.1 6.2 1.8 1 0 0 1 1 1 0 Ring finger domain G-patch PF01585.18 KUM65943.1 - 1.5e-06 27.8 0.2 0.00022 20.9 0.1 2.4 2 0 0 2 2 2 2 G-patch domain DUF4187 PF13821.1 KUM65943.1 - 0.0049 16.4 0.3 0.016 14.7 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) BLOC1_2 PF10046.4 KUM65943.1 - 0.094 12.8 0.3 0.094 12.8 0.2 1.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DbpA PF03880.10 KUM65945.1 - 0.0057 16.2 0.1 0.016 14.8 0.0 1.8 2 0 0 2 2 2 1 DbpA RNA binding domain COesterase PF00135.23 KUM65946.1 - 9.3e-22 77.4 0.0 1.1e-21 77.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.23 KUM65947.1 - 9.1e-53 179.7 0.0 1e-52 179.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KUM65947.1 - 0.0082 15.7 0.0 0.022 14.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Aminotran_5 PF00266.14 KUM65949.1 - 3.2e-47 161.0 0.0 4e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KUM65949.1 - 0.00064 18.1 0.0 0.0011 17.3 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Glyco_hydro_11 PF00457.12 KUM65950.1 - 1.4e-70 236.4 21.6 1.6e-70 236.1 15.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DUF606 PF04657.8 KUM65951.1 - 0.48 10.5 3.8 1.3 9.1 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF606 Pyridox_oxidase PF01243.15 KUM65953.1 - 0.025 14.5 0.0 0.056 13.4 0.0 1.7 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase DUF1772 PF08592.6 KUM65954.1 - 8.8e-26 90.3 3.9 1.1e-25 89.9 2.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) MFS_1 PF07690.11 KUM65955.1 - 9.5e-40 136.3 49.8 9.5e-40 136.3 34.5 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM65955.1 - 2.7e-16 58.8 20.2 6.4e-16 57.6 14.0 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FMO-like PF00743.14 KUM65956.1 - 1.9e-35 122.1 0.0 6.5e-20 70.8 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KUM65956.1 - 3.3e-18 66.4 0.1 1.6e-17 64.2 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KUM65956.1 - 2e-09 37.6 0.0 1.3e-08 35.0 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM65956.1 - 2.9e-09 36.8 0.5 1.4e-08 34.6 0.1 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 KUM65956.1 - 2.2e-08 33.3 0.1 2.1e-05 23.6 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 KUM65956.1 - 3.6e-07 29.4 1.2 2.7e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 KUM65956.1 - 4.5e-07 30.1 0.1 0.00077 19.8 0.6 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM65956.1 - 2.4e-06 27.4 0.0 1.1e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 KUM65956.1 - 0.0019 18.3 0.0 0.33 11.0 0.1 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 KUM65956.1 - 0.0033 15.9 1.1 0.015 13.7 0.4 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 KUM65956.1 - 0.013 14.5 1.1 0.024 13.7 0.7 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KUM65956.1 - 0.014 14.5 1.6 0.026 13.6 0.3 2.1 3 0 0 3 3 3 0 Thi4 family Amino_oxidase PF01593.19 KUM65956.1 - 0.022 13.8 0.0 0.97 8.4 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.1 KUM65956.1 - 0.059 13.6 0.0 13 6.1 0.0 2.8 3 0 0 3 3 3 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 KUM65956.1 - 0.066 12.8 0.3 0.15 11.7 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMO-like PF00743.14 KUM65957.1 - 1.9e-35 122.0 0.0 2.1e-18 65.8 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KUM65957.1 - 7.1e-17 62.1 0.5 3.5e-16 59.8 0.2 2.1 2 1 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KUM65957.1 - 5.4e-10 39.4 0.0 8.7e-05 22.4 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KUM65957.1 - 3.3e-07 29.5 1.0 5.5e-05 22.2 1.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 KUM65957.1 - 8.6e-07 28.1 0.4 0.0017 17.3 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KUM65957.1 - 2.2e-06 27.6 0.0 6.4e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KUM65957.1 - 6e-05 22.8 2.6 0.0032 17.2 1.9 3.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding 3HCDH_N PF02737.13 KUM65957.1 - 0.0042 16.7 0.6 0.0074 15.9 0.4 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 KUM65957.1 - 0.006 15.0 0.6 0.01 14.3 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 KUM65957.1 - 0.0069 15.5 0.1 0.016 14.3 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 KUM65957.1 - 0.0076 16.6 1.0 0.0076 16.6 0.7 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KUM65957.1 - 0.01 15.2 0.1 0.11 11.8 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 KUM65957.1 - 0.011 15.7 0.3 0.042 13.8 0.2 2.0 3 0 0 3 3 2 0 NADH(P)-binding FAD_binding_3 PF01494.14 KUM65957.1 - 0.012 14.7 0.3 0.023 13.7 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.19 KUM65957.1 - 0.019 13.8 0.4 0.038 12.8 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 KUM65957.1 - 0.067 12.5 0.1 0.16 11.2 0.0 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 KUM65957.1 - 0.075 13.1 0.5 30 4.7 0.1 3.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 KUM65957.1 - 0.084 11.9 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_2 PF03446.10 KUM65957.1 - 0.099 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Semialdhyde_dh PF01118.19 KUM65957.1 - 0.1 12.9 0.3 0.89 9.8 0.0 2.5 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain GIDA PF01134.17 KUM65957.1 - 0.18 10.6 1.1 0.29 9.9 0.7 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A ADH_zinc_N PF00107.21 KUM65958.1 - 3e-11 42.9 0.0 6.1e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF4265 PF14085.1 KUM65958.1 - 0.00068 19.3 0.0 1.6 8.5 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4265) ADH_N PF08240.7 KUM65958.1 - 0.037 13.7 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 KUM65958.1 - 0.047 13.5 0.1 0.08 12.8 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Metallophos PF00149.23 KUM65959.1 - 1.6e-05 24.3 0.2 3.6e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SPRY PF00622.23 KUM65960.1 - 0.003 17.6 0.0 0.02 14.9 0.0 2.4 2 1 1 3 3 3 1 SPRY domain Amidase PF01425.16 KUM65961.1 - 1.8e-113 379.6 0.9 2.3e-113 379.3 0.6 1.0 1 0 0 1 1 1 1 Amidase bZIP_2 PF07716.10 KUM65962.1 - 2.4e-11 43.2 21.1 2.6e-11 43.1 11.2 2.4 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 KUM65962.1 - 5.7e-06 26.1 16.0 1.1e-05 25.2 11.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 KUM65962.1 - 0.00093 19.4 13.7 0.00093 19.4 9.5 1.6 2 0 0 2 2 2 1 bZIP Maf transcription factor CENP-Q PF13094.1 KUM65962.1 - 0.59 10.1 14.8 0.54 10.2 9.3 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit APG6 PF04111.7 KUM65962.1 - 1.2 8.0 10.0 1.9 7.4 6.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Bystin PF05291.6 KUM65963.1 - 1.9e-127 424.4 0.0 2.6e-127 423.9 0.0 1.1 1 0 0 1 1 1 1 Bystin DUF1517 PF07466.6 KUM65964.1 - 0.52 9.2 1.8 0.85 8.5 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Snf7 PF03357.16 KUM65965.1 - 2.3e-06 27.0 9.2 2.8e-06 26.8 6.4 1.1 1 0 0 1 1 1 1 Snf7 Zn_clus PF00172.13 KUM65966.1 - 1.3e-06 28.2 8.6 2.1e-06 27.5 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Protocadherin PF08374.6 KUM65966.1 - 0.16 11.5 1.0 0.23 11.0 0.7 1.3 1 0 0 1 1 1 0 Protocadherin Dickkopf_N PF04706.7 KUM65966.1 - 2.9 8.1 13.6 0.29 11.3 2.5 2.3 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region YrhK PF14145.1 KUM65967.1 - 0.0067 16.0 18.2 0.055 13.1 1.3 4.1 4 1 0 4 4 4 3 YrhK-like protein SnoaL_2 PF12680.2 KUM65968.1 - 0.015 15.6 0.0 0.11 12.9 0.0 2.1 2 0 0 2 2 2 0 SnoaL-like domain SnoaL PF07366.7 KUM65968.1 - 0.037 13.6 0.0 0.077 12.5 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase MFS_1 PF07690.11 KUM65969.1 - 1.9e-41 141.9 54.1 1.9e-41 141.9 37.5 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM65969.1 - 3.2e-09 35.8 16.3 3.2e-09 35.8 11.3 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter ATG22 PF11700.3 KUM65969.1 - 3.3 6.0 34.6 0.013 14.0 9.8 3.1 3 1 0 3 3 3 0 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KUM65970.1 - 3.1e-19 68.9 10.6 3.1e-19 68.9 7.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM65970.1 - 9e-10 37.6 8.8 2e-09 36.5 4.3 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter DUF788 PF05620.6 KUM65970.1 - 0.023 14.5 0.1 0.12 12.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF788) MFS_1 PF07690.11 KUM65971.1 - 1.7e-34 119.1 30.9 1.7e-34 119.1 21.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily GDC-P PF02347.11 KUM65972.1 - 1.7e-171 570.6 0.0 8.2e-159 528.8 0.0 2.3 2 0 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 KUM65972.1 - 1.7e-05 24.1 0.2 3.1e-05 23.2 0.2 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KUM65972.1 - 0.038 13.0 0.0 0.087 11.8 0.0 1.5 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Amidohydro_1 PF01979.15 KUM65973.1 - 3.1e-31 109.2 0.0 4.2e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KUM65973.1 - 0.00017 20.9 1.4 0.014 14.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KUM65973.1 - 0.005 16.6 0.0 0.013 15.2 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KUM65973.1 - 0.033 14.2 0.5 4.2 7.3 0.0 2.5 2 0 0 2 2 2 0 Amidohydrolase A_deaminase PF00962.17 KUM65973.1 - 0.053 12.4 0.0 0.085 11.7 0.0 1.3 1 0 0 1 1 1 0 Adenosine/AMP deaminase RhgB_N PF09284.5 KUM65974.1 - 1.4e-115 384.9 5.7 1.4e-115 384.9 3.9 1.5 2 0 0 2 2 2 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 KUM65974.1 - 5.3e-61 205.0 0.1 1.1e-58 197.5 0.0 2.6 2 0 0 2 2 2 2 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 KUM65974.1 - 6.5e-18 64.6 3.3 6.5e-18 64.6 2.3 2.3 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 KUM65974.1 - 0.0021 18.0 0.8 0.0021 18.0 0.6 3.4 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain DUF2012 PF09430.5 KUM65974.1 - 0.11 12.2 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) NAD_binding_2 PF03446.10 KUM65975.1 - 1e-14 54.6 0.0 2.1e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KUM65975.1 - 1.1e-08 35.3 0.0 4.8e-08 33.3 0.0 2.1 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KUM65975.1 - 2e-06 27.9 0.0 4.2e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 KUM65975.1 - 0.00055 19.6 0.0 0.0015 18.1 0.0 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KUM65975.1 - 0.00061 18.9 0.0 0.00097 18.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KUM65975.1 - 0.0026 17.4 0.0 0.0057 16.4 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 KUM65975.1 - 0.0075 15.7 0.0 0.014 14.8 0.0 1.5 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.7 KUM65975.1 - 0.012 14.9 0.0 0.038 13.3 0.0 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain IF-2B PF01008.12 KUM65977.1 - 2.5e-74 249.8 4.4 2.8e-74 249.6 3.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Rad60-SLD PF11976.3 KUM65979.1 - 5.7e-21 73.9 0.2 5.7e-18 64.3 0.4 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KUM65979.1 - 0.0027 17.0 0.0 0.17 11.2 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin family TSGP1 PF07771.6 KUM65979.1 - 1.5 8.6 4.8 4.1 7.3 3.3 1.7 1 0 0 1 1 1 0 Tick salivary peptide group 1 LSM PF01423.17 KUM65980.1 - 1.4e-15 56.6 0.1 1.6e-15 56.3 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KUM65980.1 - 0.00075 19.3 0.0 0.00089 19.1 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain SPAN PF02510.9 KUM65980.1 - 0.14 11.2 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Surface presentation of antigens protein N-SET PF11764.3 KUM65981.1 - 9.3e-48 162.2 1.8 9.3e-48 162.2 1.2 2.1 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 KUM65981.1 - 4e-24 83.6 0.7 7.7e-24 82.7 0.5 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.23 KUM65981.1 - 7.8e-24 84.8 0.2 7.8e-24 84.8 0.2 3.0 2 2 0 2 2 2 1 SET domain RRM_1 PF00076.17 KUM65981.1 - 0.00085 18.9 0.0 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trm112p PF03966.11 KUM65982.1 - 2.2e-15 56.7 0.1 2.6e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.1 KUM65982.1 - 0.046 13.9 0.5 0.087 13.0 0.4 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zinc_ribbon_5 PF13719.1 KUM65982.1 - 0.11 12.1 0.1 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Fcf1 PF04900.7 KUM65983.1 - 4.5e-39 132.6 0.1 7.8e-39 131.8 0.1 1.4 1 0 0 1 1 1 1 Fcf1 XPG_I_2 PF12813.2 KUM65984.1 - 1.7e-79 266.7 0.0 2.3e-79 266.3 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 KUM65984.1 - 0.00035 20.5 0.0 0.00086 19.3 0.0 1.6 1 0 0 1 1 1 1 XPG I-region zf-met PF12874.2 KUM65985.1 - 0.0053 16.9 0.4 0.0093 16.1 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KUM65985.1 - 0.0053 17.0 1.2 0.013 15.7 0.8 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KUM65985.1 - 0.0087 16.3 0.3 0.024 14.9 0.2 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KUM65985.1 - 0.034 14.0 0.6 0.063 13.2 0.4 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KUM65985.1 - 0.081 13.0 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KUM65985.1 - 0.24 11.6 2.4 0.43 10.7 1.7 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Transket_pyr PF02779.19 KUM65986.1 - 1.2e-46 158.4 0.0 1.9e-46 157.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KUM65986.1 - 8.3e-36 122.6 0.2 4.7e-35 120.2 0.0 2.3 3 0 0 3 3 3 1 Transketolase, C-terminal domain adh_short_C2 PF13561.1 KUM65987.1 - 3.6e-23 82.5 0.0 1.3e-22 80.7 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.21 KUM65987.1 - 1.2e-21 77.3 0.1 3.1e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 KUM65987.1 - 5.8e-19 68.0 0.1 1.3e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 KUM65987.1 - 7.2e-11 41.9 1.0 1.6e-10 40.8 0.0 2.1 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 KUM65987.1 - 4.4e-06 26.7 0.0 1.3e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM65987.1 - 0.00093 18.9 0.0 0.0032 17.1 0.0 1.9 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 KUM65988.1 - 2.6e-83 279.9 0.0 1.8e-81 273.9 0.0 3.2 4 0 0 4 4 4 1 Acyl transferase domain MaoC_dehydratas PF01575.14 KUM65988.1 - 1.4e-39 134.2 0.0 3.6e-39 132.9 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 KUM65988.1 - 6e-30 102.8 0.1 2.5e-29 100.8 0.1 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 KUM65988.1 - 1.1e-19 70.5 0.0 3.9e-19 68.7 0.0 2.0 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.10 KUM65988.1 - 0.0081 15.3 1.0 0.056 12.5 0.7 2.2 1 1 0 1 1 1 1 Nitronate monooxygenase TRM PF02005.11 KUM65989.1 - 3.4e-115 384.9 0.0 9.5e-99 330.8 0.0 2.2 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 KUM65989.1 - 7.8e-05 22.3 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.1 KUM65989.1 - 0.00012 21.7 0.0 0.00023 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF2067 PF09840.4 KUM65989.1 - 0.0038 16.7 0.0 0.0084 15.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2067) Methyltransf_18 PF12847.2 KUM65989.1 - 0.024 15.2 0.0 0.051 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KUM65989.1 - 0.044 12.8 0.1 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 KUM65989.1 - 0.12 11.7 0.1 0.51 9.6 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase small domain UPF0561 PF10573.4 KUM65989.1 - 0.27 11.1 3.2 0.6 9.9 2.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 Trypan_PARP PF05887.6 KUM65989.1 - 2.6 7.8 12.9 0.16 11.7 1.6 2.9 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) DUF1691 PF07950.6 KUM65990.1 - 1.6e-50 169.6 7.2 1.1e-33 115.4 2.2 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF1691) VirB8 PF04335.8 KUM65990.1 - 0.25 10.9 1.4 0.39 10.2 0.9 1.2 1 0 0 1 1 1 0 VirB8 protein DUF383 PF04063.9 KUM65991.1 - 3.9e-73 245.1 0.8 3.8e-72 241.8 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 KUM65991.1 - 3.6e-23 80.8 1.6 3.4e-22 77.7 0.6 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF384) SMK-1 PF04802.10 KUM65991.1 - 0.011 15.2 0.4 0.53 9.7 0.1 2.4 2 1 0 2 2 2 0 Component of IIS longevity pathway SMK-1 Proteasom_PSMB PF10508.4 KUM65991.1 - 0.04 12.1 0.8 0.76 7.9 0.2 2.3 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit DUF2674 PF10879.3 KUM65991.1 - 0.13 11.9 0.1 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2674) OPT PF03169.10 KUM65992.1 - 1.7e-201 670.9 39.9 2e-201 670.7 27.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TFIIF_alpha PF05793.7 KUM65994.1 - 3.2e-09 35.7 53.7 7.7e-09 34.4 3.5 3.1 1 1 3 4 4 4 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) adh_short PF00106.20 KUM65995.1 - 3.4e-33 114.9 0.3 4.2e-33 114.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM65995.1 - 9.5e-26 91.0 0.0 1.1e-25 90.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM65995.1 - 7.1e-11 42.0 0.1 1.2e-10 41.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM65995.1 - 0.0051 16.2 0.8 0.011 15.2 0.5 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF137 PF02006.11 KUM65995.1 - 0.0071 15.7 0.1 0.011 15.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF137 THF_DHG_CYH_C PF02882.14 KUM65995.1 - 0.012 14.7 0.2 0.023 13.7 0.2 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HAD PF12710.2 KUM65995.1 - 0.03 14.4 0.0 0.048 13.8 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Eno-Rase_NADH_b PF12242.3 KUM65995.1 - 0.037 13.8 0.2 0.14 11.9 0.1 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DFP PF04127.10 KUM65995.1 - 0.14 11.7 0.8 0.47 10.0 0.6 1.8 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Peptidase_S10 PF00450.17 KUM65996.1 - 1.6e-93 314.1 0.0 2e-93 313.8 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase MFS_1 PF07690.11 KUM65997.1 - 8.5e-36 123.3 26.4 8.5e-36 123.3 18.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 KUM65997.1 - 2.8e-05 23.6 1.5 9.1e-05 22.0 1.1 1.9 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 CoA_trans PF01144.18 KUM66000.1 - 1.8e-99 331.3 1.0 3.9e-60 202.7 0.0 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 KUM66000.1 - 0.0022 17.6 0.1 0.004 16.8 0.1 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain p450 PF00067.17 KUM66001.1 - 8.9e-74 248.6 0.0 1.1e-73 248.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KUM66002.1 - 4.6e-29 101.2 28.7 3.8e-15 55.4 10.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KUM66002.1 - 7e-07 27.9 23.0 0.00018 20.0 0.8 3.2 3 0 0 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.19 KUM66002.1 - 1.4e-05 23.9 19.2 2.6e-05 23.0 13.3 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 KUM66002.1 - 0.13 10.3 7.8 0.059 11.4 1.4 2.5 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.2 KUM66002.1 - 0.36 10.6 12.3 1 9.2 0.2 4.3 4 1 1 5 5 5 0 MFS_1 like family Mid2 PF04478.7 KUM66003.1 - 0.0034 16.8 0.1 0.0058 16.0 0.1 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor NAD_binding_1 PF00175.16 KUM66004.1 - 9.3e-33 113.0 0.0 2.6e-32 111.6 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KUM66004.1 - 1.5e-26 92.4 0.0 3.3e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 KUM66004.1 - 1.5e-23 82.3 0.1 2.4e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 KUM66004.1 - 2.9e-07 30.5 0.0 0.00011 22.0 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KUM66004.1 - 0.0001 22.2 0.0 0.00027 20.8 0.0 1.7 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain MDMPI_N PF11716.3 KUM66004.1 - 0.011 16.1 0.3 0.023 15.1 0.2 1.6 1 1 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain GreA_GreB PF01272.14 KUM66004.1 - 0.063 12.9 0.0 0.33 10.6 0.0 2.1 2 0 0 2 2 2 0 Transcription elongation factor, GreA/GreB, C-term Gemini_AL2 PF01440.11 KUM66005.1 - 0.25 11.4 3.8 0.23 11.5 1.6 1.7 1 1 0 1 1 1 0 Geminivirus AL2 protein RTA1 PF04479.8 KUM66006.1 - 2.6e-57 193.9 9.7 2.9e-57 193.7 6.7 1.0 1 0 0 1 1 1 1 RTA1 like protein DUF4234 PF14018.1 KUM66006.1 - 1.4 8.6 7.4 12 5.7 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4234) DUF2534 PF10749.4 KUM66006.1 - 2.4 8.1 6.3 3.6 7.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2534) NAD_binding_10 PF13460.1 KUM66007.1 - 1.9e-06 27.9 0.0 2.4e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KUM66007.1 - 0.0053 15.7 0.0 0.013 14.4 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.19 KUM66007.1 - 0.014 15.6 0.0 0.034 14.4 0.0 1.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KUM66007.1 - 0.055 12.3 0.0 0.072 11.9 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KUM66007.1 - 0.071 11.9 0.1 9.1 5.0 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain Saccharop_dh PF03435.13 KUM66007.1 - 0.093 11.6 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase MIP PF00230.15 KUM66008.1 - 2.8e-28 98.9 7.6 3.6e-28 98.5 5.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein Utp21 PF04192.7 KUM66009.1 - 5e-84 281.1 0.0 8.7e-84 280.3 0.0 1.4 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 KUM66009.1 - 1.2e-17 62.9 25.2 0.0003 20.5 0.2 8.7 9 0 0 9 9 9 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KUM66009.1 - 0.071 11.3 0.2 0.6 8.3 0.0 2.3 2 1 1 3 3 3 0 Cytochrome D1 heme domain BBS2_Mid PF14783.1 KUM66009.1 - 0.15 11.8 0.0 0.77 9.5 0.0 2.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region ABC2_membrane PF01061.19 KUM66010.1 - 5.3e-60 202.1 44.6 5.1e-35 120.5 8.7 3.9 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 KUM66010.1 - 2.8e-36 124.8 0.0 2.2e-18 66.9 0.0 2.8 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 KUM66010.1 - 2.8e-26 91.1 1.7 1e-22 79.7 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter AAA_25 PF13481.1 KUM66010.1 - 3.9e-08 32.9 0.6 0.0015 17.9 0.0 3.9 4 1 0 4 4 4 2 AAA domain ABC2_membrane_3 PF12698.2 KUM66010.1 - 3.4e-06 26.3 31.5 7.3e-05 21.9 9.4 2.6 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 KUM66010.1 - 6.1e-05 23.1 0.0 0.24 11.3 0.0 3.1 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 KUM66010.1 - 0.0001 21.5 0.3 0.00068 18.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 KUM66010.1 - 0.0001 21.7 0.6 0.062 12.7 0.1 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 KUM66010.1 - 0.00017 21.0 0.8 0.0044 16.5 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KUM66010.1 - 0.00031 20.8 0.0 0.2 11.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KUM66010.1 - 0.00062 20.0 0.0 0.39 11.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KUM66010.1 - 0.0018 18.2 0.6 0.081 12.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain ATP-synt_ab PF00006.20 KUM66010.1 - 0.0019 17.7 0.3 1.2 8.5 0.3 3.1 3 1 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.1 KUM66010.1 - 0.0027 16.8 0.0 0.15 11.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.1 KUM66010.1 - 0.0028 17.6 0.3 0.031 14.2 0.2 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KUM66010.1 - 0.0052 16.4 0.0 0.82 9.3 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_17 PF13207.1 KUM66010.1 - 0.0057 17.4 0.1 1.1 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KUM66010.1 - 0.0059 16.3 1.2 0.84 9.4 0.1 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 KUM66010.1 - 0.017 15.0 0.1 0.29 11.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 KUM66010.1 - 0.056 12.9 0.3 0.54 9.7 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SbcCD_C PF13558.1 KUM66010.1 - 0.092 12.6 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 KUM66010.1 - 0.15 12.2 1.4 21 5.3 0.1 3.0 3 0 0 3 3 3 0 RNA helicase Arch_ATPase PF01637.13 KUM66010.1 - 0.15 11.6 0.0 15 5.1 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_30 PF13604.1 KUM66010.1 - 0.18 11.3 0.7 6.2 6.3 0.0 2.6 3 0 0 3 3 2 0 AAA domain T2SE PF00437.15 KUM66010.1 - 0.25 10.1 0.1 10 4.9 0.0 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein UPF0079 PF02367.12 KUM66010.1 - 0.26 10.9 2.3 0.8 9.3 0.0 2.5 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 KUM66010.1 - 0.27 11.5 0.0 0.59 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Abhydrolase_6 PF12697.2 KUM66011.1 - 9e-37 127.1 0.0 1e-36 126.9 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KUM66011.1 - 7.1e-21 74.8 0.1 1.1e-15 57.8 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KUM66011.1 - 5.7e-19 68.2 0.2 1e-17 64.2 0.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 KUM66011.1 - 0.00065 19.3 0.0 0.0012 18.4 0.0 1.4 2 0 0 2 2 2 1 Serine hydrolase Hydrolase_4 PF12146.3 KUM66011.1 - 0.0083 15.9 0.0 0.039 13.8 0.0 2.2 1 1 1 2 2 2 1 Putative lysophospholipase FBPase_glpX PF03320.8 KUM66011.1 - 0.012 14.3 0.1 0.017 13.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded DUF1057 PF06342.7 KUM66011.1 - 0.04 12.7 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) LCAT PF02450.10 KUM66011.1 - 0.043 12.7 0.0 0.068 12.1 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PGAP1 PF07819.8 KUM66011.1 - 0.047 13.2 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF1749 PF08538.5 KUM66011.1 - 0.07 12.0 0.0 0.12 11.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) DUF2305 PF10230.4 KUM66011.1 - 0.16 11.3 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Fungal_trans PF04082.13 KUM66012.1 - 3.2e-17 62.2 0.0 4.9e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM66012.1 - 1e-06 28.5 11.3 1.9e-06 27.6 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAGK_cat PF00781.19 KUM66013.1 - 1.6e-10 40.5 0.0 3e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Ribonuc_L-PSP PF01042.16 KUM66014.1 - 5.3e-20 71.3 0.0 6.5e-20 71.0 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Grp1_Fun34_YaaH PF01184.14 KUM66015.1 - 9.8e-32 109.9 17.7 1.1e-31 109.7 12.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3935 PF13071.1 KUM66015.1 - 1 9.8 0.0 1 9.8 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3935) His_Phos_2 PF00328.17 KUM66016.1 - 6.1e-118 394.1 0.1 7.7e-118 393.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 KUM66016.1 - 3.9e-06 26.4 0.0 9.3e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Inositol_P PF00459.20 KUM66017.1 - 2.4e-65 220.5 0.0 2.8e-65 220.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF676 PF05057.9 KUM66018.1 - 3.1e-42 144.3 0.0 8.3e-29 100.4 0.0 3.2 3 0 0 3 3 3 3 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 KUM66018.1 - 0.0017 18.1 0.0 0.0042 16.8 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KUM66018.1 - 0.0018 17.9 0.0 0.0039 16.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF915 PF06028.6 KUM66018.1 - 0.012 14.7 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.8 KUM66018.1 - 0.069 12.7 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein EMP70 PF02990.11 KUM66020.1 - 5.3e-157 523.4 1.4 2.6e-156 521.1 1.0 2.1 1 1 0 1 1 1 1 Endomembrane protein 70 DUF3929 PF13066.1 KUM66021.1 - 0.029 14.1 0.1 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3929) adh_short PF00106.20 KUM66025.1 - 7.3e-14 52.0 0.6 1.1e-13 51.4 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM66025.1 - 7.8e-06 25.6 1.2 1.8e-05 24.5 0.8 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KUM66025.1 - 1.1e-05 25.3 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF3425 PF11905.3 KUM66026.1 - 2.7e-28 98.5 0.3 3.5e-28 98.1 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) CN_hydrolase PF00795.17 KUM66027.1 - 2.1e-21 76.1 0.0 3.1e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Sulfatase PF00884.18 KUM66028.1 - 8.7e-60 202.4 0.2 1.3e-59 201.9 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 KUM66028.1 - 5.5e-22 77.3 0.8 1.3e-21 76.1 0.6 1.7 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 KUM66028.1 - 3.5e-08 33.1 0.7 5.7e-06 25.8 0.5 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 KUM66028.1 - 0.0014 18.9 0.3 0.011 15.9 0.1 2.2 1 1 1 2 2 2 1 C-terminal region of aryl-sulfatase DUF229 PF02995.12 KUM66028.1 - 0.0017 16.8 0.0 0.0022 16.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.13 KUM66028.1 - 0.008 15.5 0.0 0.021 14.2 0.0 1.7 2 0 0 2 2 2 1 Metalloenzyme superfamily DUF1501 PF07394.7 KUM66028.1 - 0.012 14.4 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) NmrA PF05368.8 KUM66029.1 - 9.2e-60 201.7 0.1 1.2e-59 201.4 0.1 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KUM66029.1 - 2.9e-14 53.4 0.2 4.3e-14 52.9 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KUM66029.1 - 3.4e-08 32.5 0.0 4.6e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KUM66029.1 - 0.0027 17.2 0.1 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KUM66029.1 - 0.0046 15.9 0.3 0.0093 14.9 0.1 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 KUM66029.1 - 0.013 15.5 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain Semialdhyde_dh PF01118.19 KUM66029.1 - 0.067 13.4 0.0 0.45 10.8 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 KUM66029.1 - 0.086 12.7 0.4 0.14 12.0 0.2 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Bac_luciferase PF00296.15 KUM66030.1 - 1.6e-59 201.5 0.7 2e-59 201.2 0.5 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Trypsin_2 PF13365.1 KUM66031.1 - 0.097 12.6 0.0 0.22 11.5 0.0 1.6 2 0 0 2 2 2 0 Trypsin-like peptidase domain Methyltransf_2 PF00891.13 KUM66033.1 - 1.7e-17 63.4 0.0 3.5e-17 62.4 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Dpy-30 PF05186.8 KUM66034.1 - 0.36 10.3 1.6 0.95 8.9 0.5 2.1 2 1 0 2 2 2 0 Dpy-30 motif NAD_binding_6 PF08030.7 KUM66035.1 - 4.6e-22 78.5 0.0 7.4e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KUM66035.1 - 1.9e-20 72.6 0.0 4.8e-20 71.3 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KUM66035.1 - 1.1e-17 64.2 9.6 3e-17 62.8 6.7 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KUM66035.1 - 1.1e-05 25.4 0.0 3.2e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KUM66035.1 - 0.15 12.6 0.0 1.6 9.3 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain 7TMR-DISM_7TM PF07695.6 KUM66036.1 - 0.14 11.8 2.9 0.19 11.3 1.7 1.3 1 1 0 1 1 1 0 7TM diverse intracellular signalling UDG PF03167.14 KUM66037.1 - 2e-19 69.5 0.2 6.8e-18 64.5 0.0 2.1 2 0 0 2 2 2 2 Uracil DNA glycosylase superfamily SBDS PF01172.13 KUM66038.1 - 8.9e-25 86.3 0.1 1e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein XkdN PF08890.6 KUM66038.1 - 0.0026 17.4 0.0 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 Phage XkdN-like protein RhoGEF PF00621.15 KUM66039.1 - 3.8e-22 79.0 0.1 1.3e-21 77.2 0.0 2.0 1 1 0 1 1 1 1 RhoGEF domain BP28CT PF08146.7 KUM66040.1 - 1.6e-42 144.8 1.4 7.5e-42 142.6 0.6 2.6 2 1 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 KUM66040.1 - 8.1e-30 103.2 0.1 8.1e-30 103.2 0.1 6.1 7 0 0 7 7 7 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 KUM66040.1 - 4.7e-10 39.6 1.3 0.065 13.5 0.0 6.3 6 1 0 6 6 6 3 HEAT repeats HEAT PF02985.17 KUM66040.1 - 4.2e-05 23.2 2.0 0.33 11.1 0.0 6.4 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 KUM66040.1 - 0.0008 19.8 10.4 1.5 9.3 0.1 7.3 5 2 1 6 6 6 1 HEAT-like repeat CARD PF00619.16 KUM66040.1 - 0.029 14.2 0.2 0.029 14.2 0.1 2.4 3 0 0 3 3 3 0 Caspase recruitment domain ABC_tran PF00005.22 KUM66041.1 - 3.8e-45 153.5 0.0 3.1e-27 95.5 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 KUM66041.1 - 1e-28 100.5 26.2 2.1e-15 56.8 9.6 3.1 3 1 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.14 KUM66041.1 - 7.2e-13 48.2 4.4 1.7e-05 24.1 1.2 4.2 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KUM66041.1 - 9e-11 42.2 0.0 0.097 12.6 0.0 4.3 3 1 0 4 4 4 3 AAA domain AAA_22 PF13401.1 KUM66041.1 - 2.7e-08 33.9 0.1 0.0032 17.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KUM66041.1 - 5.1e-07 29.1 2.1 0.00088 18.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 KUM66041.1 - 1.2e-06 28.0 0.1 0.0054 16.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KUM66041.1 - 3e-06 27.6 0.4 0.014 15.7 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KUM66041.1 - 2.1e-05 24.5 6.5 0.24 11.3 0.0 3.9 4 1 0 4 4 3 2 AAA ATPase domain T2SE PF00437.15 KUM66041.1 - 3.4e-05 22.8 2.3 0.049 12.5 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein NACHT PF05729.7 KUM66041.1 - 0.00012 21.7 0.4 0.69 9.5 0.0 3.1 3 0 0 3 3 2 2 NACHT domain FtsK_SpoIIIE PF01580.13 KUM66041.1 - 0.0002 20.9 0.1 0.17 11.3 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family Miro PF08477.8 KUM66041.1 - 0.00022 21.7 0.7 0.37 11.2 0.0 3.1 3 0 0 3 3 2 1 Miro-like protein DUF258 PF03193.11 KUM66041.1 - 0.001 18.2 0.3 1.4 8.0 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.12 KUM66041.1 - 0.0012 18.7 1.4 0.006 16.4 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_10 PF12846.2 KUM66041.1 - 0.0021 17.5 1.7 0.16 11.3 0.0 3.1 3 1 0 3 3 3 1 AAA-like domain cobW PF02492.14 KUM66041.1 - 0.0053 16.2 1.5 0.19 11.1 0.1 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 KUM66041.1 - 0.0066 16.4 0.4 0.65 9.9 0.1 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 KUM66041.1 - 0.0096 16.2 0.0 3 8.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KUM66041.1 - 0.01 15.7 0.7 4.7 7.0 0.1 3.0 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KUM66041.1 - 0.014 16.2 2.6 0.7 10.7 0.2 3.2 3 1 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.12 KUM66041.1 - 0.018 14.5 0.0 7.3 6.0 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein MobB PF03205.9 KUM66041.1 - 0.029 14.0 0.9 0.7 9.5 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 KUM66041.1 - 0.031 14.2 0.0 5.9 6.8 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit TrwB_AAD_bind PF10412.4 KUM66041.1 - 0.042 12.4 1.6 0.79 8.2 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.10 KUM66041.1 - 0.045 13.4 0.7 10 5.8 0.0 2.6 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.1 KUM66041.1 - 0.051 13.1 4.5 6.3 6.3 0.8 3.0 2 1 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KUM66041.1 - 0.089 12.4 0.5 0.52 9.9 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 KUM66041.1 - 0.12 11.4 0.4 2.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 KUM66041.1 - 0.13 12.0 7.7 0.78 9.5 0.2 3.8 3 1 0 3 3 3 0 Part of AAA domain DUF2075 PF09848.4 KUM66041.1 - 0.14 11.0 1.3 4.8 6.0 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 KUM66041.1 - 0.15 12.2 0.0 8.8 6.5 0.0 3.0 2 0 0 2 2 2 0 RNA helicase Pox_A32 PF04665.7 KUM66041.1 - 0.25 10.5 1.4 11 5.2 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_13 PF13166.1 KUM66041.1 - 0.26 9.6 0.9 4.7 5.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 KUM66041.1 - 0.92 9.3 9.6 1.3 8.8 0.1 3.2 4 0 0 4 4 3 0 Dynamin family Zot PF05707.7 KUM66041.1 - 1.2 8.5 4.2 2.4 7.5 0.0 3.0 3 1 0 3 3 2 0 Zonular occludens toxin (Zot) SCP2 PF02036.12 KUM66042.1 - 6.9e-26 90.5 0.6 8.4e-26 90.2 0.4 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 KUM66042.1 - 1.5e-06 28.2 0.1 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Ras PF00071.17 KUM66045.1 - 4.4e-49 165.9 0.0 5.3e-49 165.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KUM66045.1 - 1.8e-14 54.2 0.0 3.5e-14 53.3 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KUM66045.1 - 1.2e-10 40.9 0.0 1.5e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 KUM66045.1 - 0.0005 20.2 0.1 0.004 17.2 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 KUM66045.1 - 0.00087 18.4 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KUM66045.1 - 0.014 14.1 1.6 0.93 8.1 0.1 2.9 2 1 1 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.7 KUM66045.1 - 0.022 14.0 0.1 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 KUM66045.1 - 0.056 13.5 0.1 0.2 11.7 0.1 1.8 1 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KUM66045.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 KUM66045.1 - 0.097 11.8 0.0 0.16 11.1 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PDZ_2 PF13180.1 KUM66046.1 - 1.4e-08 34.4 0.1 2.6e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 KUM66046.1 - 4.5e-06 26.7 0.1 7.6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) GRASP55_65 PF04495.9 KUM66046.1 - 2.2e-05 24.4 0.0 3.7e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain DUF3336 PF11815.3 KUM66046.1 - 0.032 13.7 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3336) FAT PF02259.18 KUM66046.1 - 0.065 12.2 0.0 0.07 12.1 0.0 1.1 1 0 0 1 1 1 0 FAT domain F-box-like PF12937.2 KUM66047.1 - 0.0059 16.3 0.5 0.076 12.7 0.1 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KUM66047.1 - 0.087 12.5 1.4 0.33 10.6 0.1 2.4 2 0 0 2 2 2 0 F-box domain SNF2_N PF00176.18 KUM66048.1 - 2.1e-71 240.2 0.1 2.8e-71 239.7 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KUM66048.1 - 1.2e-12 47.5 0.0 3.8e-12 45.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 KUM66048.1 - 4e-08 32.8 3.2 7.6e-08 31.9 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KUM66048.1 - 5e-08 32.8 6.1 1e-07 31.8 4.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 KUM66048.1 - 6.9e-07 29.2 0.4 1.1e-05 25.3 0.0 2.7 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 KUM66048.1 - 9.4e-05 21.9 5.6 0.00018 21.0 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KUM66048.1 - 0.00011 21.9 4.4 0.00022 20.9 3.1 1.5 1 0 0 1 1 1 1 Ring finger domain DEAD PF00270.24 KUM66048.1 - 0.00021 20.8 0.0 0.00054 19.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_4 PF15227.1 KUM66048.1 - 0.00095 18.9 5.0 0.0021 17.9 3.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KUM66048.1 - 0.0046 16.6 1.7 0.011 15.4 1.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 KUM66048.1 - 0.06 12.9 5.5 0.19 11.3 3.6 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 KUM66048.1 - 0.19 11.5 6.7 0.85 9.3 5.0 1.9 1 1 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.1 KUM66048.1 - 3.2 7.3 6.8 13 5.4 4.7 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Aa_trans PF01490.13 KUM66049.1 - 4.2e-09 35.3 6.1 5.6e-09 34.9 4.2 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.1 KUM66049.1 - 0.0029 17.2 3.4 0.014 15.0 0.4 2.1 2 0 0 2 2 2 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase ABC2_membrane_5 PF13346.1 KUM66049.1 - 0.054 12.7 5.7 0.073 12.3 4.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2976 PF11190.3 KUM66049.1 - 0.099 12.1 1.4 2.8 7.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Cation_ATPase_C PF00689.16 KUM66049.1 - 0.11 11.9 5.9 1.6 8.2 1.3 2.1 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus DUF4149 PF13664.1 KUM66049.1 - 6.1 6.9 8.7 9.3 6.3 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) Aa_trans PF01490.13 KUM66050.1 - 1.3e-30 106.1 14.4 1.6e-30 105.8 9.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KUM66050.1 - 0.00099 18.0 14.3 0.0012 17.7 9.9 1.3 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family PDZ_1 PF12812.2 KUM66051.1 - 2.7e-52 174.5 0.0 2.4e-33 113.8 0.0 2.6 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.1 KUM66051.1 - 5e-14 52.3 0.3 1.5e-13 50.7 0.0 2.0 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 KUM66051.1 - 4.2e-11 42.5 0.1 2.5e-05 24.0 0.0 4.5 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.19 KUM66051.1 - 0.00016 21.7 0.0 0.017 15.2 0.0 3.3 3 0 0 3 3 3 1 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 KUM66051.1 - 0.018 14.8 0.5 0.65 9.8 0.1 3.1 3 0 0 3 3 3 0 Tricorn protease PDZ domain Peptidase_S46 PF10459.4 KUM66051.1 - 0.33 9.3 0.1 0.65 8.3 0.0 1.4 2 0 0 2 2 2 0 Peptidase S46 TPR_11 PF13414.1 KUM66052.1 - 8.5e-09 34.9 11.9 8.7e-08 31.7 0.5 2.8 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 KUM66052.1 - 9.4e-08 31.4 3.0 0.029 14.2 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KUM66052.1 - 1.5e-06 27.5 3.6 0.026 14.1 0.2 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 KUM66052.1 - 0.049 13.8 0.4 0.85 9.9 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KUM66052.1 - 0.061 14.0 0.6 0.061 14.0 0.4 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KUM66052.1 - 0.069 13.2 1.2 0.15 12.2 0.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Glyco_hydro_10 PF00331.15 KUM66053.1 - 4.1e-89 298.7 0.2 5.3e-89 298.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF4339 PF14237.1 KUM66053.1 - 0.07 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) FumaraseC_C PF10415.4 KUM66053.1 - 0.1 12.6 0.0 0.38 10.8 0.0 1.9 3 0 0 3 3 3 0 Fumarase C C-terminus DUF2841 PF11001.3 KUM66054.1 - 4.5e-41 139.6 2.5 5.1e-41 139.4 0.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) SSXT PF05030.7 KUM66055.1 - 1.8e-05 24.1 0.0 0.22 11.1 0.0 2.3 2 0 0 2 2 2 2 SSXT protein (N-terminal region) DUF1313 PF07011.6 KUM66055.1 - 0.098 12.3 0.0 15 5.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1313) Rab5-bind PF09311.6 KUM66056.1 - 0.002 18.0 7.1 0.23 11.3 1.4 2.3 1 1 1 2 2 2 2 Rabaptin-like protein Viral_env_E26 PF11050.3 KUM66056.1 - 0.01 15.0 1.8 0.013 14.6 1.3 1.1 1 0 0 1 1 1 0 Virus envelope protein E26 Mnd1 PF03962.10 KUM66056.1 - 0.098 12.3 1.2 0.15 11.7 0.9 1.3 1 0 0 1 1 1 0 Mnd1 family DUF4140 PF13600.1 KUM66056.1 - 0.98 9.8 4.7 18 5.8 3.2 2.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) TMF_TATA_bd PF12325.3 KUM66056.1 - 2 8.1 7.0 0.68 9.6 0.7 2.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.3 KUM66056.1 - 2 8.2 7.3 1.6 8.5 3.3 2.1 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Iso_dh PF00180.15 KUM66057.1 - 9.6e-110 366.7 0.0 1.1e-109 366.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Pyridoxal_deC PF00282.14 KUM66058.1 - 2.9e-76 256.3 0.0 3.9e-76 255.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain AMP-binding PF00501.23 KUM66059.1 - 9.5e-48 162.6 0.0 1.3e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme peroxidase PF00141.18 KUM66061.1 - 8.5e-46 156.2 0.0 1.3e-45 155.7 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Peptidase_S10 PF00450.17 KUM66062.1 - 9e-126 420.3 0.2 1.1e-125 420.0 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 KUM66062.1 - 2.1e-10 40.7 0.0 3.6e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 KUM66062.1 - 0.0042 16.9 0.0 0.12 12.2 0.0 2.7 3 0 0 3 3 3 1 Alpha/beta hydrolase family Ribosomal_S13 PF00416.17 KUM66063.1 - 9.2e-42 141.8 1.7 1.2e-41 141.5 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF1822 PF08852.6 KUM66063.1 - 0.011 14.6 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) FbpA PF05833.6 KUM66063.1 - 0.013 14.1 0.0 0.013 14.0 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF2746 PF10874.3 KUM66063.1 - 0.061 13.5 0.2 2.8 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) HHH_6 PF14579.1 KUM66063.1 - 0.075 13.0 0.1 0.15 12.0 0.0 1.6 1 1 0 1 1 1 0 Helix-hairpin-helix motif PALP PF00291.20 KUM66064.1 - 7.8e-36 123.8 0.6 9.9e-36 123.5 0.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Mucin PF01456.12 KUM66064.1 - 0.5 10.1 17.9 0.38 10.5 11.2 1.7 1 1 0 1 1 1 0 Mucin-like glycoprotein SBDS_C PF09377.5 KUM66065.1 - 2.4e-51 172.6 0.1 4e-51 171.9 0.1 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 KUM66065.1 - 1.3e-26 92.2 0.1 2.8e-26 91.1 0.0 1.6 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Cohesin_HEAT PF12765.2 KUM66065.1 - 0.036 14.0 0.2 0.43 10.5 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Bac_luciferase PF00296.15 KUM66068.1 - 9.2e-60 202.3 2.8 1.2e-59 202.0 1.9 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase SSF PF00474.12 KUM66069.1 - 8.7e-21 74.0 30.5 8.7e-21 74.0 21.1 1.7 3 0 0 3 3 3 1 Sodium:solute symporter family Glyco_hydro_18 PF00704.23 KUM66070.1 - 1e-96 324.3 9.4 1.2e-96 324.1 6.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.8 KUM66070.1 - 0.002 17.3 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 EthD PF07110.6 KUM66071.1 - 3.7e-18 66.2 0.5 4.3e-18 66.0 0.3 1.1 1 0 0 1 1 1 1 EthD domain Bul1_N PF04425.7 KUM66072.1 - 7.3e-07 28.0 3.9 1.4e-05 23.8 0.3 2.7 1 1 1 2 2 2 2 Bul1 N terminus Arrestin_N PF00339.24 KUM66072.1 - 2.5e-06 27.3 0.0 1.2e-05 25.1 0.0 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 KUM66072.1 - 0.0094 15.1 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Bul1 C terminus CPSF_A PF03178.10 KUM66073.1 - 1.4e-99 333.2 0.0 2.2e-98 329.2 0.0 2.5 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 KUM66073.1 - 8.1e-67 225.4 0.0 1.4e-66 224.7 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term BBS2_N PF14781.1 KUM66073.1 - 0.033 13.8 0.0 8.6 5.9 0.0 3.0 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal ubiquitin PF00240.18 KUM66074.1 - 2e-18 65.5 0.1 3.3e-18 64.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 KUM66074.1 - 4.6e-09 35.8 1.8 6.2e-09 35.4 0.0 2.2 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.3 KUM66074.1 - 1.6e-08 34.0 0.0 2.5e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KUM66074.1 - 1.9e-05 24.7 0.0 3.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain YukD PF08817.5 KUM66074.1 - 5.1e-05 23.7 0.0 9.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD Rad60-SLD_2 PF13881.1 KUM66074.1 - 0.00012 21.9 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KUM66074.1 - 0.063 13.5 0.2 0.19 11.9 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain RTA1 PF04479.8 KUM66075.1 - 3e-45 154.4 7.1 3e-45 154.4 4.9 1.5 2 0 0 2 2 2 1 RTA1 like protein NRDE-2 PF08424.5 KUM66076.1 - 2.4e-76 256.6 0.6 4.3e-75 252.5 0.0 2.2 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 KUM66076.1 - 0.044 14.4 10.3 5 8.0 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR_3 PF13812.1 KUM66076.1 - 1.4 9.4 3.6 1.3e+02 3.1 0.0 4.6 5 0 0 5 5 5 0 Pentatricopeptide repeat domain zf-CCHC_3 PF13917.1 KUM66077.1 - 2.9e-12 46.1 0.8 3.3e-08 33.1 0.0 2.6 2 0 0 2 2 2 2 Zinc knuckle SUZ PF12752.2 KUM66078.1 - 7.9e-20 71.1 0.8 7.9e-20 71.1 0.5 2.6 2 0 0 2 2 2 1 SUZ domain R3H PF01424.17 KUM66078.1 - 2.8e-06 26.9 0.0 6.4e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 R3H domain DUF1242 PF06842.7 KUM66079.1 - 3.2e-18 64.9 0.2 4.6e-18 64.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) TFIID-18kDa PF02269.11 KUM66080.1 - 1e-23 82.9 0.0 1.7e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-S PF15630.1 KUM66080.1 - 0.00025 21.1 0.0 0.0005 20.1 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 KUM66080.1 - 0.00036 20.5 0.4 0.00098 19.1 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 KUM66080.1 - 0.0035 17.0 0.0 0.0068 16.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 KUM66080.1 - 0.0043 17.3 0.0 0.0076 16.5 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TAF PF02969.12 KUM66080.1 - 0.025 14.5 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 KUM66080.1 - 0.084 12.9 0.1 0.084 12.9 0.1 2.5 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Herpes_BLLF1 PF05109.8 KUM66080.1 - 9.1 4.1 34.5 15 3.3 23.9 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) PPR_2 PF13041.1 KUM66082.1 - 5.3e-12 45.5 3.5 5.6e-06 26.2 0.1 5.0 5 1 1 6 6 6 3 PPR repeat family PPR_3 PF13812.1 KUM66082.1 - 3.7e-09 36.1 1.3 0.053 13.8 0.0 6.3 6 0 0 6 6 6 2 Pentatricopeptide repeat domain PPR PF01535.15 KUM66082.1 - 1e-07 31.4 0.1 0.017 15.0 0.0 3.9 4 0 0 4 4 4 2 PPR repeat PPR_1 PF12854.2 KUM66082.1 - 4e-05 22.9 0.0 0.0051 16.2 0.0 2.9 2 0 0 2 2 2 1 PPR repeat Rhomboid PF01694.17 KUM66084.1 - 6e-20 71.7 9.3 6e-20 71.7 6.4 1.7 2 0 0 2 2 2 1 Rhomboid family ATG16 PF08614.6 KUM66085.1 - 0.017 14.9 0.1 0.021 14.6 0.1 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) NAD_binding_6 PF08030.7 KUM66085.1 - 0.074 12.9 0.0 0.081 12.8 0.0 1.1 1 0 0 1 1 1 0 Ferric reductase NAD binding domain IncA PF04156.9 KUM66085.1 - 0.2 11.2 0.7 0.24 10.9 0.5 1.1 1 0 0 1 1 1 0 IncA protein DUF904 PF06005.7 KUM66085.1 - 0.4 11.0 3.4 1.1 9.5 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Mob1_phocein PF03637.12 KUM66086.1 - 2.5e-30 105.4 1.1 3.2e-14 52.9 0.0 2.2 2 0 0 2 2 2 2 Mob1/phocein family NdhO PF11910.3 KUM66086.1 - 0.055 13.1 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Cyanobacterial and plant NDH-1 subunit O AA_permease_2 PF13520.1 KUM66087.1 - 8.6e-38 129.9 49.7 1.1e-37 129.6 34.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM66087.1 - 1.3e-26 92.9 44.7 1.8e-26 92.5 31.0 1.0 1 0 0 1 1 1 1 Amino acid permease Herpes_US9 PF06072.6 KUM66087.1 - 4 7.3 0.0 4 7.3 0.0 4.1 4 0 0 4 4 4 0 Alphaherpesvirus tegument protein US9 PhoD PF09423.5 KUM66088.1 - 1.7e-13 49.9 0.3 6.9e-08 31.4 0.1 2.4 2 1 0 2 2 2 2 PhoD-like phosphatase Ammonium_transp PF00909.16 KUM66089.1 - 0.041 12.3 6.9 0.06 11.8 4.8 1.1 1 0 0 1 1 1 0 Ammonium Transporter Family MraZ PF02381.13 KUM66090.1 - 0.06 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 MraZ protein EFG_C PF00679.19 KUM66090.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.4 1 1 0 1 1 1 0 Elongation factor G C-terminus Leo1 PF04004.8 KUM66091.1 - 2.2e-29 102.3 0.7 3.5e-29 101.7 0.0 1.7 2 0 0 2 2 2 1 Leo1-like protein CTP_transf_2 PF01467.21 KUM66093.1 - 5e-21 75.3 0.0 7.8e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase YhhN PF07947.9 KUM66094.1 - 1.8e-45 154.5 11.6 2.2e-45 154.3 8.1 1.1 1 0 0 1 1 1 1 YhhN-like protein PP2C PF00481.16 KUM66095.1 - 2.7e-80 269.4 0.0 3.5e-80 269.0 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KUM66095.1 - 0.00029 20.3 0.0 0.00054 19.4 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C DUF3655 PF12379.3 KUM66096.1 - 0.13 12.1 1.5 0.18 11.7 1.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3655) Phage_B PF02304.10 KUM66096.1 - 1.2 9.4 4.3 1.4 9.2 3.0 1.2 1 0 0 1 1 1 0 Scaffold protein B CASP_C PF08172.7 KUM66097.1 - 0.11 11.4 0.1 0.36 9.8 0.0 1.7 2 0 0 2 2 2 0 CASP C terminal DUF1253 PF06862.7 KUM66098.1 - 2.5e-160 533.6 0.0 3.4e-160 533.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) FoP_duplication PF13865.1 KUM66098.1 - 0.2 12.1 13.3 0.51 10.8 9.2 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 EamA PF00892.15 KUM66100.1 - 2.6e-17 63.0 30.6 3.3e-12 46.5 6.8 3.5 3 1 1 4 4 4 3 EamA-like transporter family EmrE PF13536.1 KUM66100.1 - 2.2e-06 27.8 33.0 3.4e-06 27.2 2.6 3.8 2 2 1 4 4 4 2 Multidrug resistance efflux transporter Ank_4 PF13637.1 KUM66101.1 - 7.3e-33 112.3 3.9 1.1e-07 32.1 0.0 5.3 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.2 KUM66101.1 - 1.4e-27 95.8 0.0 4.1e-10 39.8 0.0 4.0 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KUM66101.1 - 6.8e-24 82.4 10.7 0.00026 20.6 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 KUM66101.1 - 2.4e-19 68.9 1.7 3.7e-06 26.9 0.0 6.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM66101.1 - 1.1e-12 46.8 4.4 0.086 13.1 0.0 7.6 8 0 0 8 8 8 3 Ankyrin repeat NACHT PF05729.7 KUM66101.1 - 3e-06 27.0 0.1 8.7e-06 25.4 0.0 1.8 1 1 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.15 KUM66101.1 - 0.00012 21.1 0.1 0.0068 15.4 0.0 2.8 3 1 0 3 3 3 1 Phosphorylase superfamily AAA_16 PF13191.1 KUM66101.1 - 0.0071 16.3 4.5 0.5 10.3 0.2 4.0 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KUM66101.1 - 0.02 15.0 0.2 0.2 11.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.11 KUM66102.1 - 1e-33 116.5 45.6 4.1e-32 111.2 30.2 3.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KUM66102.1 - 5.4e-14 51.3 23.4 1.7e-13 49.6 16.2 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.20 KUM66103.1 - 7.7e-14 51.9 0.2 2.1e-13 50.5 0.1 1.8 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 KUM66103.1 - 1.2e-06 28.3 0.1 2.2e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.11 KUM66104.1 - 0.0001 21.1 4.3 0.00011 21.0 3.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Ribosom_S12_S23 PF00164.20 KUM66105.1 - 1.9e-40 137.1 0.5 2.1e-40 136.9 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 IF-2B PF01008.12 KUM66106.1 - 2.7e-63 213.6 0.5 9.7e-38 129.7 0.0 2.3 2 1 0 2 2 2 2 Initiation factor 2 subunit family NIF PF03031.13 KUM66107.1 - 8.4e-55 184.7 0.0 1.4e-54 184.0 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Glyco_hydro_76 PF03663.9 KUM66108.1 - 2.9e-140 467.8 22.4 3.6e-140 467.5 15.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DAO PF01266.19 KUM66109.1 - 1.4e-22 80.1 0.0 1.7e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KUM66109.1 - 0.00045 20.5 1.6 0.0017 18.6 0.7 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KUM66109.1 - 0.0041 16.0 0.0 0.0057 15.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 KUM66109.1 - 0.016 15.4 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.9 KUM66109.1 - 0.022 14.6 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM66109.1 - 0.029 14.3 0.3 0.066 13.2 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 KUM66109.1 - 0.034 14.1 0.7 0.077 12.9 0.5 1.6 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.14 KUM66109.1 - 0.051 12.6 0.5 0.085 11.8 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.11 KUM66109.1 - 0.07 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 KUM66109.1 - 0.1 11.7 0.3 0.19 10.8 0.2 1.4 1 0 0 1 1 1 0 Thi4 family MFS_1 PF07690.11 KUM66110.1 - 1.1e-30 106.6 32.0 1.1e-30 106.6 22.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM66110.1 - 3.8e-11 42.2 21.6 6.3e-11 41.5 15.0 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter N2227 PF07942.7 KUM66113.1 - 4.2e-59 199.7 0.0 5e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 KUM66113.1 - 5e-05 23.0 0.0 8.3e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM66113.1 - 0.00042 20.7 0.0 0.0016 18.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM66113.1 - 0.001 19.4 0.0 0.0036 17.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM66113.1 - 0.0078 16.7 0.0 0.026 15.1 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KUM66113.1 - 0.038 14.0 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KUM66113.1 - 0.092 12.3 0.0 0.41 10.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain CbiQ PF02361.11 KUM66113.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Cobalt transport protein NNMT_PNMT_TEMT PF01234.12 KUM66113.1 - 0.16 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family MFS_1 PF07690.11 KUM66114.1 - 2e-21 76.1 52.1 1.5e-14 53.5 15.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_E8 PF03394.8 KUM66114.1 - 0.007 15.7 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 Poxvirus E8 protein MFS_1_like PF12832.2 KUM66114.1 - 0.45 10.3 6.9 8 6.3 0.1 3.2 3 0 0 3 3 3 0 MFS_1 like family Polyketide_cyc2 PF10604.4 KUM66115.1 - 0.014 15.6 3.5 0.044 13.9 2.4 1.8 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport FAD_binding_3 PF01494.14 KUM66116.1 - 9.5e-52 176.2 0.0 1.4e-51 175.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Fungal_trans PF04082.13 KUM66117.1 - 7.1e-14 51.2 0.9 1.3e-13 50.4 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM66117.1 - 1e-06 28.5 13.3 2.1e-06 27.5 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3328 PF11807.3 KUM66119.1 - 0.0014 18.3 1.2 0.0024 17.6 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3328) EFG_IV PF03764.13 KUM66120.1 - 1.9e-06 27.4 1.1 15 5.1 0.0 4.9 1 1 4 5 5 5 4 Elongation factor G, domain IV SHNi-TPR PF10516.4 KUM66120.1 - 0.02 14.0 0.3 81 2.5 0.0 4.5 5 0 0 5 5 5 0 SHNi-TPR ATC_hydrolase PF14196.1 KUM66120.1 - 0.038 14.3 3.4 0.49 10.7 2.3 2.0 1 1 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Imm49 PF15660.1 KUM66120.1 - 0.043 13.8 0.4 6.3 6.9 0.0 2.4 1 1 3 4 4 4 0 Immunity protein 49 DUF3254 PF11630.3 KUM66120.1 - 0.056 13.4 0.1 22 5.1 0.0 2.5 1 1 3 4 4 4 0 Protein of unknown function (DUF3254) DUF2059 PF09832.4 KUM66120.1 - 0.058 13.4 3.2 7.5 6.6 0.1 3.1 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2059) MOZART1 PF12554.3 KUM66121.1 - 1.7e-24 84.9 1.1 2.1e-24 84.7 0.7 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated DUF1844 PF08899.6 KUM66121.1 - 0.013 15.4 0.4 0.018 14.9 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1844) WXG100 PF06013.7 KUM66121.1 - 0.014 15.4 0.1 0.21 11.6 0.1 2.0 2 0 0 2 2 2 0 Proteins of 100 residues with WXG SRP54_N PF02881.14 KUM66121.1 - 0.014 15.4 0.1 0.034 14.2 0.0 1.7 1 1 0 1 1 1 0 SRP54-type protein, helical bundle domain DUF3926 PF13080.1 KUM66121.1 - 0.17 11.4 0.9 0.22 11.0 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3926) CUE PF02845.11 KUM66122.1 - 1.6e-12 46.6 0.0 2.5e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.1 KUM66122.1 - 0.023 14.2 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain OB_NTP_bind PF07717.11 KUM66123.1 - 1.7e-23 82.6 0.0 3.1e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KUM66123.1 - 4.4e-20 71.5 0.0 7.9e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KUM66123.1 - 4.3e-13 48.9 0.0 9.1e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KUM66123.1 - 1.4e-06 28.4 0.0 3.5e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 KUM66123.1 - 2.1e-05 24.0 0.0 4.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase cobW PF02492.14 KUM66123.1 - 0.0052 16.2 0.0 0.047 13.1 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 KUM66123.1 - 0.011 14.6 0.0 0.026 13.4 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 KUM66123.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KUM66123.1 - 0.051 13.4 0.0 3.2 7.6 0.0 2.6 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KUM66123.1 - 0.087 11.9 0.2 0.3 10.1 0.0 2.0 1 1 1 2 2 2 0 Zeta toxin AAA_23 PF13476.1 KUM66123.1 - 0.16 12.2 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KUM66124.1 - 1.3e-89 297.2 0.0 8e-44 149.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KUM66124.1 - 2.8e-14 53.5 0.8 1.7e-06 28.1 0.0 4.1 2 2 2 4 4 4 2 AAA ATPase domain RuvB_N PF05496.7 KUM66124.1 - 1.5e-13 50.3 0.0 1.7e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KUM66124.1 - 2.7e-13 50.2 0.2 0.0012 18.9 0.0 5.6 3 2 1 4 4 3 2 AAA domain AAA_17 PF13207.1 KUM66124.1 - 5.9e-12 46.4 0.0 7.6e-07 29.9 0.0 3.1 2 1 1 3 3 2 2 AAA domain AAA_5 PF07728.9 KUM66124.1 - 1.1e-10 41.4 0.2 0.0014 18.3 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KUM66124.1 - 1.6e-10 41.1 0.0 0.00019 21.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 KUM66124.1 - 4e-10 39.7 0.0 0.00014 21.7 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KUM66124.1 - 4.5e-10 39.5 0.0 0.00025 20.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KUM66124.1 - 5.8e-09 35.3 0.0 0.0012 17.9 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 KUM66124.1 - 9.7e-09 34.4 0.0 8.9e-05 21.3 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 KUM66124.1 - 1.3e-08 34.4 0.1 0.0046 16.6 0.0 3.5 3 0 0 3 3 3 2 Part of AAA domain RNA_helicase PF00910.17 KUM66124.1 - 9.9e-08 32.1 0.0 0.0064 16.6 0.0 2.7 2 1 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 KUM66124.1 - 3.8e-07 29.6 1.8 0.018 14.4 0.0 2.9 3 1 0 3 3 3 2 IstB-like ATP binding protein AAA_25 PF13481.1 KUM66124.1 - 4.7e-07 29.3 3.2 1.2 8.4 0.0 4.6 2 2 2 4 4 4 3 AAA domain AAA_28 PF13521.1 KUM66124.1 - 9.2e-07 28.9 0.0 0.019 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KUM66124.1 - 1e-06 29.0 0.0 0.012 15.8 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_3 PF07726.6 KUM66124.1 - 1.5e-06 27.8 0.0 0.0053 16.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 KUM66124.1 - 1.6e-06 27.4 0.3 0.038 13.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KUM66124.1 - 5.4e-06 26.1 0.2 0.61 9.7 0.0 4.1 3 1 1 4 4 4 2 NACHT domain KaiC PF06745.8 KUM66124.1 - 8.9e-06 24.9 0.1 0.27 10.3 0.0 3.4 2 1 1 3 3 3 2 KaiC Cytidylate_kin2 PF13189.1 KUM66124.1 - 2.3e-05 24.3 0.0 0.0036 17.2 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family PhoH PF02562.11 KUM66124.1 - 2.3e-05 23.7 0.0 0.066 12.4 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activ_2 PF14532.1 KUM66124.1 - 6.1e-05 23.0 0.0 0.41 10.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 KUM66124.1 - 6.7e-05 23.1 0.0 0.29 11.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SKI PF01202.17 KUM66124.1 - 8.3e-05 22.5 0.0 0.27 11.1 0.0 2.7 2 0 0 2 2 2 2 Shikimate kinase Sigma54_activat PF00158.21 KUM66124.1 - 0.0001 21.8 0.0 0.26 10.7 0.0 3.0 3 0 0 3 3 3 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 KUM66124.1 - 0.0002 21.1 0.0 1.9 8.0 0.0 3.7 2 2 1 3 3 3 1 Archaeal ATPase NB-ARC PF00931.17 KUM66124.1 - 0.00039 19.3 0.0 0.27 10.0 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Rad17 PF03215.10 KUM66124.1 - 0.00078 18.2 0.0 0.27 9.8 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein ResIII PF04851.10 KUM66124.1 - 0.0013 18.6 0.0 2.1 8.1 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AFG1_ATPase PF03969.11 KUM66124.1 - 0.0014 17.5 0.1 0.68 8.6 0.0 3.0 2 1 0 2 2 2 1 AFG1-like ATPase Parvo_NS1 PF01057.12 KUM66124.1 - 0.002 17.0 0.0 1.3 7.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 KUM66124.1 - 0.0024 17.4 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 KUM66124.1 - 0.0055 16.2 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 KUM66124.1 - 0.0062 16.1 0.0 2 8.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 DUF815 PF05673.8 KUM66124.1 - 0.0075 15.2 0.0 0.078 11.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NTPase_1 PF03266.10 KUM66124.1 - 0.013 15.2 0.0 2 8.0 0.0 3.0 2 1 1 3 3 3 0 NTPase DUF2075 PF09848.4 KUM66124.1 - 0.016 14.1 0.0 1.4 7.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ATP-synt_ab PF00006.20 KUM66124.1 - 0.016 14.6 0.0 1.9 7.9 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.1 KUM66124.1 - 0.02 14.5 0.1 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.5 KUM66124.1 - 0.028 13.6 0.0 24 4.0 0.0 3.3 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit CPT PF07931.7 KUM66124.1 - 0.037 13.6 0.0 1 8.9 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein IPT PF01745.11 KUM66124.1 - 0.043 12.9 0.0 4.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase KTI12 PF08433.5 KUM66124.1 - 0.15 11.2 0.1 43 3.1 0.0 3.1 3 0 0 3 3 3 0 Chromatin associated protein KTI12 BOP1NT PF08145.7 KUM66125.1 - 1.6e-109 365.6 7.8 2.4e-109 365.0 5.4 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 KUM66125.1 - 3.1e-25 87.0 9.5 2.1e-10 40.0 0.2 6.1 7 1 0 7 7 7 4 WD domain, G-beta repeat He_PIG PF05345.7 KUM66126.1 - 4.6e-15 55.3 4.7 0.00053 19.9 0.1 4.6 4 0 0 4 4 4 3 Putative Ig domain SKG6 PF08693.5 KUM66126.1 - 1.3e-06 27.6 0.3 2.6e-06 26.6 0.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Acetyltransf_1 PF00583.19 KUM66127.1 - 4.7e-12 45.7 0.2 8.7e-12 44.9 0.1 1.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KUM66127.1 - 4.3e-09 36.0 0.0 6.7e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KUM66127.1 - 5.5e-08 32.8 0.1 7.8e-08 32.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KUM66127.1 - 9.3e-07 28.9 0.0 1.1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 KUM66127.1 - 3.6e-05 23.7 0.0 5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KUM66127.1 - 5.2e-05 23.1 0.0 9e-05 22.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 KUM66127.1 - 0.0012 18.4 0.3 0.0016 18.0 0.2 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KUM66127.1 - 0.0029 17.4 0.1 0.0052 16.6 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 KUM66127.1 - 0.057 13.5 0.0 0.068 13.3 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KUM66127.1 - 0.076 12.9 0.0 0.081 12.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_L17 PF01196.14 KUM66129.1 - 4e-30 104.2 0.2 1.1e-29 102.8 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L17 Mg_chelatase_2 PF13335.1 KUM66129.1 - 0.23 11.8 4.7 0.11 12.8 0.7 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI cwf18 PF08315.7 KUM66130.1 - 2e-39 134.9 5.4 3.4e-39 134.2 3.8 1.4 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor HK97-gp10_like PF04883.7 KUM66130.1 - 0.18 12.7 4.0 0.71 10.8 0.7 2.3 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component RskA PF10099.4 KUM66131.1 - 0.067 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA EphA2_TM PF14575.1 KUM66131.1 - 0.069 13.5 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1191 PF06697.7 KUM66131.1 - 0.1 11.4 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF1510 PF07423.6 KUM66131.1 - 0.54 9.5 0.1 0.54 9.5 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1510) Ank PF00023.25 KUM66132.1 - 1.3e-46 154.1 12.3 7.6e-08 31.7 0.1 6.6 7 0 0 7 7 7 6 Ankyrin repeat Ank_2 PF12796.2 KUM66132.1 - 3.3e-43 145.9 2.7 1.3e-18 67.1 0.2 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KUM66132.1 - 4e-33 113.1 6.1 9.4e-10 38.7 0.0 5.8 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM66132.1 - 2.1e-31 107.1 11.2 4.2e-07 29.9 0.1 6.0 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM66132.1 - 2.9e-31 104.3 3.0 1.9e-05 24.4 0.0 6.4 7 0 0 7 7 7 6 Ankyrin repeat RVP PF00077.15 KUM66132.1 - 0.012 15.5 0.1 0.37 10.7 0.0 2.5 2 0 0 2 2 2 0 Retroviral aspartyl protease DUF2984 PF11203.3 KUM66132.1 - 0.31 11.1 1.7 0.29 11.2 0.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2984) ABM PF03992.11 KUM66134.1 - 0.041 13.9 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Metallophos PF00149.23 KUM66135.1 - 0.077 12.3 4.6 0.18 11.1 3.2 1.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase PITH PF06201.8 KUM66136.1 - 4.2e-43 146.7 0.0 5.1e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 PITH domain Snf7 PF03357.16 KUM66137.1 - 6.6e-35 120.0 3.0 8.1e-35 119.7 2.1 1.1 1 0 0 1 1 1 1 Snf7 MR_MLE_N PF02746.11 KUM66137.1 - 0.026 14.5 0.1 0.11 12.5 0.1 1.9 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF2203 PF09969.4 KUM66137.1 - 0.47 10.6 2.5 13 6.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) HSCB_C PF07743.8 KUM66137.1 - 0.57 10.6 9.6 4.5 7.7 2.1 2.4 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain RRM_1 PF00076.17 KUM66138.1 - 9.9e-16 57.1 0.0 1.7e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM66138.1 - 2.4e-14 53.0 0.0 4.6e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM66138.1 - 9.2e-06 25.4 0.0 1.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) V_ATPase_I PF01496.14 KUM66138.1 - 0.0028 15.6 0.3 0.003 15.5 0.2 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family NPV_P10 PF05531.7 KUM66138.1 - 0.046 13.9 0.5 0.084 13.1 0.3 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein HAP1_N PF04849.8 KUM66138.1 - 0.047 12.6 3.1 0.065 12.1 2.1 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region IncA PF04156.9 KUM66138.1 - 0.065 12.8 4.1 0.089 12.3 2.8 1.1 1 0 0 1 1 1 0 IncA protein CASP_C PF08172.7 KUM66138.1 - 0.067 12.2 0.1 0.083 11.9 0.1 1.1 1 0 0 1 1 1 0 CASP C terminal STAT_alpha PF01017.15 KUM66138.1 - 0.08 12.6 1.0 0.12 12.1 0.7 1.1 1 0 0 1 1 1 0 STAT protein, all-alpha domain APG6 PF04111.7 KUM66138.1 - 0.097 11.7 1.9 0.11 11.4 1.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Nup35_RRM_2 PF14605.1 KUM66138.1 - 0.099 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif BLOC1_2 PF10046.4 KUM66138.1 - 0.13 12.4 1.8 0.2 11.7 1.2 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Pox_A_type_inc PF04508.7 KUM66138.1 - 0.17 11.7 1.1 0.44 10.4 0.6 1.9 1 1 0 1 1 1 0 Viral A-type inclusion protein repeat COG6 PF06419.6 KUM66138.1 - 0.2 9.7 1.3 0.26 9.3 0.9 1.0 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 DUF904 PF06005.7 KUM66138.1 - 0.28 11.4 5.3 0.47 10.7 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Troponin PF00992.15 KUM66138.1 - 0.31 11.1 5.6 0.44 10.6 3.9 1.1 1 0 0 1 1 1 0 Troponin DUF4337 PF14235.1 KUM66138.1 - 0.35 10.6 1.5 0.48 10.2 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DivIC PF04977.10 KUM66138.1 - 0.54 9.7 4.5 0.81 9.2 3.2 1.3 1 0 0 1 1 1 0 Septum formation initiator HECT PF00632.20 KUM66139.1 - 6.5e-93 311.3 0.0 9.1e-93 310.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KUM66139.1 - 3.3e-31 106.7 18.0 1.1e-11 44.3 2.4 3.7 3 0 0 3 3 3 3 WW domain DUF2531 PF10748.4 KUM66140.1 - 0.11 11.7 7.0 2.1 7.5 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2531) Strep_his_triad PF04270.8 KUM66140.1 - 0.35 10.6 6.4 11 5.7 0.3 3.3 3 0 0 3 3 3 0 Streptococcal histidine triad protein JAB PF01398.16 KUM66141.1 - 8.7e-17 60.9 0.2 2.7e-16 59.3 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KUM66141.1 - 4.4e-16 59.0 0.3 7.9e-16 58.1 0.2 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Isochorismatase PF00857.15 KUM66144.1 - 6.5e-36 123.8 0.1 7.4e-36 123.6 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family MFS_1 PF07690.11 KUM66145.1 - 8.8e-43 146.3 61.0 1.3e-42 145.7 40.8 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM66145.1 - 8.5e-14 50.6 31.0 3.2e-13 48.7 21.5 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KUM66145.1 - 6.1e-13 48.1 12.4 6.1e-13 48.1 8.6 3.7 3 1 0 4 4 4 2 Sugar (and other) transporter DUF3357 PF11837.3 KUM66145.1 - 0.11 12.3 1.7 0.33 10.8 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) Kinocilin PF15033.1 KUM66145.1 - 2.1 7.9 7.2 1 8.8 0.0 3.7 4 0 0 4 4 4 0 Kinocilin protein Zn_clus PF00172.13 KUM66146.1 - 4.4e-08 32.8 8.0 7.9e-08 32.0 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KUM66146.1 - 2.2e-05 23.2 0.1 3.9e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SOG2 PF10428.4 KUM66147.1 - 0.026 13.1 0.5 0.033 12.8 0.3 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Cu_amine_oxid PF01179.15 KUM66148.1 - 2.7e-170 566.5 0.7 3.3e-170 566.3 0.5 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KUM66148.1 - 8.8e-07 28.9 0.0 1.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KUM66148.1 - 1.1e-06 28.5 0.0 2.2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DAP_B PF07930.7 KUM66149.1 - 0.095 12.4 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 D-aminopeptidase, domain B TFIIA PF03153.8 KUM66150.1 - 8.3 6.1 7.5 11 5.7 5.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Abhydrolase_4 PF08386.5 KUM66151.1 - 1.2e-25 89.4 0.0 2.5e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KUM66151.1 - 1.8e-13 50.6 0.1 4.7e-12 45.9 0.1 2.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KUM66151.1 - 7.3e-08 32.5 1.1 5.4e-06 26.4 0.3 3.1 1 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM66151.1 - 0.0016 18.2 0.0 0.022 14.5 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Aldolase_II PF00596.16 KUM66152.1 - 8.8e-47 159.0 0.1 1.3e-46 158.5 0.1 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain ATP-synt_Eps PF04627.8 KUM66153.1 - 3.6e-23 80.8 1.6 3.6e-23 80.8 1.1 1.4 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain DDE_1 PF03184.14 KUM66155.1 - 7.5e-18 64.4 0.2 1.3e-17 63.6 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease bZIP_2 PF07716.10 KUM66155.1 - 0.16 11.8 1.3 0.38 10.6 0.9 1.6 1 0 0 1 1 1 0 Basic region leucine zipper ORC6 PF05460.8 KUM66155.1 - 1.5 7.8 11.1 2.6 7.0 7.7 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Acetyltransf_7 PF13508.1 KUM66156.1 - 4.7e-08 33.0 0.2 1.5e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KUM66156.1 - 5.2e-07 29.6 0.2 1.3e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KUM66156.1 - 8.2e-05 22.4 0.2 0.00016 21.5 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KUM66156.1 - 0.00049 20.2 0.5 0.0072 16.4 0.4 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KUM66156.1 - 0.0025 17.5 0.0 0.0053 16.4 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 KUM66156.1 - 0.0058 16.5 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Cellulase PF00150.13 KUM66157.1 - 2.3e-17 63.1 7.8 3e-17 62.7 5.4 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF624 PF04854.9 KUM66157.1 - 0.072 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF624 Het-C PF07217.6 KUM66158.1 - 0.081 11.1 3.2 2.9 5.9 0.1 2.6 2 1 0 2 2 2 0 Heterokaryon incompatibility protein Het-C DUF3427 PF11907.3 KUM66158.1 - 0.22 10.4 0.8 11 4.9 0.1 3.3 2 2 2 4 4 4 0 Domain of unknown function (DUF3427) TFIIA PF03153.8 KUM66158.1 - 0.26 11.1 9.6 0.41 10.4 6.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 KUM66158.1 - 1.5 7.0 7.9 2.1 6.5 5.5 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF3206 PF11472.3 KUM66158.1 - 1.7 8.4 8.3 3.4 7.4 0.2 4.2 3 1 2 5 5 5 0 Protein of unknown function (DUF3206) Fungal_trans PF04082.13 KUM66159.1 - 6.1e-07 28.5 1.2 9.9e-07 27.8 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM66160.1 - 7.6e-09 35.3 11.1 1.4e-08 34.5 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 KUM66160.1 - 0.86 9.8 11.7 1.9 8.7 8.1 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Mak10 PF04112.8 KUM66161.1 - 2.5e-55 186.2 0.0 4.3e-55 185.4 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase OB_NTP_bind PF07717.11 KUM66163.1 - 4.7e-20 71.5 0.0 1.1e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KUM66163.1 - 9.3e-17 60.9 0.4 9.3e-17 60.9 0.3 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KUM66163.1 - 3.5e-13 49.1 0.0 3.9e-12 45.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KUM66163.1 - 3.9e-05 23.2 0.0 0.00012 21.6 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KUM66163.1 - 0.0013 18.9 0.0 0.0033 17.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KUM66163.1 - 0.0033 16.9 0.0 0.008 15.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KUM66163.1 - 0.0084 15.5 0.0 0.02 14.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KUM66163.1 - 0.016 14.1 0.0 0.033 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 KUM66163.1 - 0.024 13.7 0.0 0.38 9.8 0.0 2.2 2 0 0 2 2 2 0 KaiC zf-MYND PF01753.13 KUM66165.1 - 3.1e-09 36.5 16.7 3.1e-09 36.5 11.5 1.7 2 0 0 2 2 2 1 MYND finger HSP20 PF00011.16 KUM66166.1 - 5.4e-13 48.6 0.3 7.6e-13 48.1 0.2 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Arylsulfotran_2 PF14269.1 KUM66167.1 - 1.9e-57 194.6 1.4 2.6e-57 194.2 1.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KUM66167.1 - 4e-14 51.9 0.3 7.3e-14 51.1 0.2 1.4 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) RAMP4 PF06624.7 KUM66167.1 - 0.009 15.5 0.3 0.018 14.5 0.2 1.4 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Mg_trans_NIPA PF05653.9 KUM66168.1 - 3.4e-95 318.4 16.6 4e-95 318.2 11.5 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KUM66168.1 - 1.3e-08 34.9 2.1 1.3e-08 34.9 1.4 3.4 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 KUM66168.1 - 0.00032 20.7 3.2 0.00032 20.7 2.2 3.5 3 1 1 4 4 4 1 EamA-like transporter family Acyl_transf_3 PF01757.17 KUM66168.1 - 0.0036 16.1 3.3 0.0036 16.1 2.3 2.2 1 1 1 2 2 2 1 Acyltransferase family MreB_Mbl PF06723.8 KUM66169.1 - 0.0056 15.3 0.0 0.056 12.0 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein HSP70 PF00012.15 KUM66169.1 - 0.026 12.4 0.0 0.097 10.5 0.0 1.7 2 0 0 2 2 2 0 Hsp70 protein Methyltransf_32 PF13679.1 KUM66170.1 - 4.9e-20 71.6 0.0 7.7e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KUM66172.1 - 5e-09 36.3 1.8 5.2e-09 36.2 0.1 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site Mito_fiss_reg PF05308.6 KUM66172.1 - 0.39 10.0 2.9 2.1 7.6 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF4470 PF14737.1 KUM66173.1 - 4.3e-21 74.5 0.1 7.9e-21 73.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) Laminin_II PF06009.7 KUM66175.1 - 0.073 12.8 1.1 4.4 7.0 0.4 2.4 2 0 0 2 2 2 0 Laminin Domain II Z1 PF10593.4 KUM66175.1 - 0.11 11.7 0.4 0.21 10.7 0.0 1.7 2 0 0 2 2 2 0 Z1 domain IncA PF04156.9 KUM66175.1 - 0.18 11.3 2.7 0.33 10.5 1.9 1.4 1 0 0 1 1 1 0 IncA protein MFS_1 PF07690.11 KUM66176.1 - 5.8e-35 120.6 22.2 4e-34 117.8 16.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1049 PF06305.6 KUM66176.1 - 0.22 10.9 2.5 0.49 9.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) ABC2_membrane PF01061.19 KUM66177.1 - 1.1e-89 299.1 50.6 9.8e-48 162.0 11.9 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KUM66177.1 - 5e-40 136.9 0.0 6.6e-19 68.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KUM66177.1 - 7.7e-32 109.0 7.1 1.1e-30 105.3 0.0 3.3 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 KUM66177.1 - 8.2e-11 41.5 37.9 1.1e-05 24.7 13.8 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 KUM66177.1 - 1.1e-06 28.1 0.2 0.00099 18.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 KUM66177.1 - 7.7e-06 26.0 0.2 0.11 12.6 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_33 PF13671.1 KUM66177.1 - 0.00013 21.8 0.0 0.48 10.2 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KUM66177.1 - 0.00066 20.4 0.0 0.51 11.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KUM66177.1 - 0.0007 19.5 1.2 0.32 10.9 0.2 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KUM66177.1 - 0.00078 18.9 1.2 0.32 10.4 0.2 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 KUM66177.1 - 0.00086 18.5 0.1 0.009 15.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KUM66177.1 - 0.00097 18.6 1.4 0.077 12.5 0.1 3.3 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KUM66177.1 - 0.0024 17.9 0.6 0.69 9.8 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KUM66177.1 - 0.0029 17.9 0.1 2 8.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KUM66177.1 - 0.0036 16.9 1.1 1.7 8.2 0.2 2.5 2 0 0 2 2 2 2 NACHT domain ABC_trans_N PF14510.1 KUM66177.1 - 0.0057 16.7 0.0 0.016 15.2 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_19 PF13245.1 KUM66177.1 - 0.01 15.5 0.3 2.7 7.8 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA PF00004.24 KUM66177.1 - 0.02 15.1 0.0 7 6.8 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 KUM66177.1 - 0.022 14.2 1.3 1.3 8.4 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.1 KUM66177.1 - 0.033 14.1 0.0 0.47 10.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain UPF0079 PF02367.12 KUM66177.1 - 0.071 12.7 1.1 5.2 6.7 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 KUM66177.1 - 0.098 12.3 0.0 10 5.7 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase Miro PF08477.8 KUM66177.1 - 0.1 13.0 0.0 3.2 8.2 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein MFS_1 PF07690.11 KUM66178.1 - 2.8e-32 111.7 57.8 1.3e-29 103.0 33.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KUM66178.1 - 2.6e-05 22.7 13.5 2.6e-05 22.7 9.3 2.7 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 KUM66178.1 - 3.1e-05 22.7 41.2 0.0093 14.5 11.3 2.3 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 KUM66178.1 - 0.00065 19.4 8.6 0.0065 16.2 0.0 3.5 4 0 0 4 4 4 2 MFS_1 like family IATP PF04568.7 KUM66179.1 - 7.9e-18 64.3 0.6 8.9e-18 64.1 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP PaaSYMP PF14738.1 KUM66179.1 - 0.029 14.1 1.0 0.037 13.7 0.7 1.1 1 0 0 1 1 1 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 Takusan PF04822.8 KUM66179.1 - 0.034 13.8 0.7 0.052 13.2 0.5 1.4 1 0 0 1 1 1 0 Takusan RIC3 PF15361.1 KUM66179.1 - 0.12 12.6 0.5 0.15 12.2 0.4 1.3 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Abhydrolase_6 PF12697.2 KUM66182.1 - 2.4e-07 30.8 0.0 2.7e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.13 KUM66182.1 - 1.3e-05 24.6 0.0 3.5e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 2) Abhydrolase_1 PF00561.15 KUM66182.1 - 0.00072 19.1 0.0 0.0024 17.4 0.0 1.8 1 1 0 2 2 2 1 alpha/beta hydrolase fold DUF900 PF05990.7 KUM66182.1 - 0.033 13.5 0.0 0.08 12.2 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.8 KUM66182.1 - 0.055 13.0 0.0 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein Ser_hydrolase PF06821.8 KUM66182.1 - 0.071 12.7 0.0 1.4 8.5 0.0 2.1 1 1 0 1 1 1 0 Serine hydrolase DUF2974 PF11187.3 KUM66182.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Zn_clus PF00172.13 KUM66183.1 - 1.1e-05 25.2 12.7 2e-05 24.3 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KUM66183.1 - 7.1e-05 21.5 0.0 0.00097 17.8 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain DRIM PF07539.7 KUM66184.1 - 0.028 13.8 0.2 0.035 13.5 0.1 1.2 1 0 0 1 1 1 0 Down-regulated in metastasis F-box-like PF12937.2 KUM66185.1 - 1.7e-08 34.0 0.0 4e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KUM66185.1 - 0.0034 17.0 0.0 0.013 15.1 0.0 2.0 2 0 0 2 2 2 1 F-box domain TPR_11 PF13414.1 KUM66185.1 - 0.0087 15.6 0.1 0.022 14.3 0.1 1.6 1 0 0 1 1 1 1 TPR repeat MIT PF04212.13 KUM66185.1 - 0.052 13.4 0.1 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.12 KUM66185.1 - 0.15 12.0 0.2 1.1 9.3 0.2 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat HAMP PF00672.20 KUM66187.1 - 4.2e-35 119.7 13.0 4.3e-09 36.4 0.2 5.8 5 0 0 5 5 5 5 HAMP domain HATPase_c PF02518.21 KUM66187.1 - 2.2e-30 104.6 0.1 5.8e-30 103.2 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KUM66187.1 - 2.5e-29 101.5 0.4 3.9e-27 94.4 0.2 3.0 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.20 KUM66187.1 - 1.8e-11 43.8 0.5 1.6e-10 40.8 0.2 2.8 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain YlqD PF11068.3 KUM66187.1 - 8.1e-05 22.6 4.4 0.42 10.6 0.0 4.7 3 1 1 5 5 5 1 YlqD protein DUF883 PF05957.8 KUM66187.1 - 0.023 15.0 4.5 13 6.2 0.1 4.3 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) AAA_13 PF13166.1 KUM66187.1 - 0.042 12.3 5.0 1.5 7.1 0.2 3.0 2 1 1 3 3 3 0 AAA domain DUF2365 PF10157.4 KUM66187.1 - 0.27 11.1 8.7 11 5.9 0.0 4.9 5 0 0 5 5 5 0 Uncharacterized conserved protein (DUF2365) DASH_Dad2 PF08654.5 KUM66187.1 - 3.1 7.8 8.6 30 4.6 0.1 4.9 6 0 0 6 6 6 0 DASH complex subunit Dad2 CENP-F_leu_zip PF10473.4 KUM66187.1 - 4.8 7.0 10.1 64 3.3 0.1 5.3 4 2 1 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.3 KUM66187.1 - 6 6.6 13.6 0.4 10.4 0.4 4.5 4 2 2 6 6 6 0 TATA element modulatory factor 1 TATA binding DUF948 PF06103.6 KUM66187.1 - 8.3 6.3 25.2 3.3 7.6 0.2 6.1 5 2 3 8 8 8 0 Bacterial protein of unknown function (DUF948) Cpn60_TCP1 PF00118.19 KUM66188.1 - 2.4e-117 392.5 4.9 2.7e-117 392.3 3.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1547 PF07577.6 KUM66188.1 - 0.24 11.0 2.1 0.57 9.8 0.2 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1547) Amidase PF01425.16 KUM66189.1 - 1.6e-42 145.9 0.1 3.2e-41 141.6 0.1 2.4 1 1 0 1 1 1 1 Amidase Glyco_hydro_32C PF08244.7 KUM66190.1 - 3.8e-17 62.4 0.1 3.3e-16 59.4 0.0 2.4 2 1 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.15 KUM66190.1 - 2.1e-12 47.0 0.0 3.4e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain B3_4 PF03483.12 KUM66191.1 - 1.6e-21 76.5 0.0 2.1e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 B3/4 domain Mito_carr PF00153.22 KUM66192.1 - 3.3e-60 199.8 0.9 1.2e-18 66.5 0.0 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF676 PF05057.9 KUM66193.1 - 1.6e-07 30.8 0.1 2.1e-06 27.1 0.0 2.3 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KUM66193.1 - 9.9e-06 25.2 0.0 4.3e-05 23.2 0.0 2.1 2 1 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KUM66193.1 - 0.00045 20.1 0.7 0.0012 18.7 0.1 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family PA28_beta PF02252.13 KUM66193.1 - 0.049 13.1 0.3 0.093 12.1 0.2 1.4 1 0 0 1 1 1 0 Proteasome activator pa28 beta subunit ketoacyl-synt PF00109.21 KUM66194.1 - 1.7e-74 250.4 0.0 3e-74 249.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KUM66194.1 - 5.1e-59 198.9 0.2 8.6e-58 194.9 0.0 2.6 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 KUM66194.1 - 4.4e-56 190.2 0.0 8.8e-56 189.2 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KUM66194.1 - 1.7e-53 182.0 0.8 1.4e-52 179.0 0.3 2.2 2 0 0 2 2 2 1 Acyl transferase domain adh_short PF00106.20 KUM66194.1 - 5.9e-44 149.9 0.1 3e-43 147.6 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KUM66194.1 - 3.6e-39 133.2 1.4 5.4e-38 129.5 0.0 3.5 4 0 0 4 4 4 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_23 PF13489.1 KUM66194.1 - 1.1e-08 34.9 0.1 2.8e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM66194.1 - 1.8e-08 34.7 0.0 6.7e-08 32.9 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain ADH_N PF08240.7 KUM66194.1 - 2.6e-05 23.9 0.4 6.7e-05 22.6 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 KUM66194.1 - 0.00013 21.0 0.1 0.00028 19.9 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_11 PF08241.7 KUM66194.1 - 0.00024 21.5 0.0 0.00073 19.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KUM66194.1 - 0.00039 20.6 0.0 0.0012 19.1 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 KUM66194.1 - 0.0013 19.3 0.0 0.0055 17.2 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KUM66194.1 - 0.0054 16.2 0.0 0.02 14.4 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 KUM66194.1 - 0.014 14.9 0.0 0.041 13.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 KUM66194.1 - 0.021 13.9 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Polysacc_synt_2 PF02719.10 KUM66194.1 - 0.11 11.4 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1212 PF06738.7 KUM66197.1 - 2.4e-57 193.5 15.9 1.7e-52 177.6 0.4 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KUM66197.1 - 3.6e-28 98.0 9.6 3.6e-28 98.0 6.7 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3815) CENP-F_N PF10481.4 KUM66197.1 - 0.18 11.1 0.2 0.28 10.5 0.2 1.2 1 0 0 1 1 1 0 Cenp-F N-terminal domain FSH1 PF03959.8 KUM66199.1 - 1.8e-29 102.7 0.0 2.1e-29 102.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Methyltransf_23 PF13489.1 KUM66200.1 - 3.6e-14 52.8 0.1 5.5e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM66200.1 - 4.4e-12 46.3 0.0 1.2e-11 44.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM66200.1 - 2.1e-11 43.6 0.0 4.3e-11 42.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM66200.1 - 3.5e-11 43.6 0.0 6.8e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM66200.1 - 1.8e-10 41.2 0.0 3.7e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM66200.1 - 6e-09 36.1 0.0 1.6e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KUM66200.1 - 1.5e-05 24.2 0.0 2.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KUM66200.1 - 4.1e-05 23.5 0.0 7.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KUM66200.1 - 0.00054 19.6 0.0 0.0009 18.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 KUM66200.1 - 0.024 15.4 0.0 0.065 14.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KUM66200.1 - 0.039 13.3 0.0 0.12 11.7 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain Zip PF02535.17 KUM66200.1 - 0.066 12.2 1.5 0.081 11.9 1.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3438 PF11920.3 KUM66200.1 - 0.16 10.7 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) DUF2946 PF11162.3 KUM66200.1 - 0.41 10.8 3.9 2.3 8.4 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) Innate_immun PF12782.2 KUM66200.1 - 2.2 7.4 9.2 3.1 6.9 6.4 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Asparaginase_II PF06089.7 KUM66201.1 - 2.6e-52 177.5 0.3 2.8e-52 177.4 0.2 1.0 1 0 0 1 1 1 1 L-asparaginase II Pyr_redox_2 PF07992.9 KUM66202.1 - 1.7e-19 70.4 0.0 2.6e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KUM66202.1 - 5.1e-06 25.5 0.0 0.00013 20.9 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KUM66202.1 - 0.00048 18.7 0.2 0.0039 15.7 0.0 2.4 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.19 KUM66202.1 - 0.00054 18.9 1.3 0.003 16.5 0.4 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KUM66202.1 - 0.0013 17.8 0.1 0.0029 16.7 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KUM66202.1 - 0.0064 16.4 0.1 0.017 15.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KUM66202.1 - 0.014 14.3 0.0 0.025 13.4 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 KUM66202.1 - 0.018 14.8 1.1 0.065 13.0 0.3 2.1 1 1 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 KUM66202.1 - 0.025 13.6 0.1 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 KUM66202.1 - 0.054 13.5 0.4 1 9.3 0.2 2.2 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KUM66202.1 - 0.08 11.5 0.1 0.19 10.2 0.1 1.6 1 0 0 1 1 1 0 Tryptophan halogenase K_oxygenase PF13434.1 KUM66202.1 - 0.1 11.5 0.1 2.1 7.1 0.1 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 KUM66202.1 - 0.66 10.4 3.0 3.3 8.1 0.1 2.9 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF3716 PF12511.3 KUM66203.1 - 4.1e-06 26.2 4.9 6.4e-06 25.6 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) p450 PF00067.17 KUM66204.1 - 1.7e-52 178.5 0.0 1.9e-52 178.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ALO PF04030.9 KUM66207.1 - 1.3e-87 293.7 0.1 1.9e-87 293.1 0.1 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 KUM66207.1 - 7.4e-32 109.7 0.1 1.3e-31 108.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Motilin_assoc PF04643.7 KUM66207.1 - 0.085 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Motilin/ghrelin-associated peptide Syja_N PF02383.13 KUM66208.1 - 1.7e-96 322.7 0.0 2.5e-96 322.1 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 KUM66208.1 - 3e-37 126.4 0.0 5.5e-37 125.6 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase Cache_2 PF08269.6 KUM66208.1 - 0.026 14.4 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 Cache domain CDP-OH_P_transf PF01066.16 KUM66209.1 - 6.5e-18 64.8 7.7 8.5e-18 64.5 4.8 1.7 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DUF4595 PF15283.1 KUM66210.1 - 0.045 13.4 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4595) with porin-like fold E1-E2_ATPase PF00122.15 KUM66211.1 - 9e-65 217.9 0.7 1.7e-64 217.0 0.5 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KUM66211.1 - 6.5e-35 120.2 8.4 6.5e-35 120.2 5.8 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KUM66211.1 - 7.6e-29 101.6 0.0 5.2e-28 98.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KUM66211.1 - 7.4e-18 63.7 0.2 2.1e-17 62.3 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KUM66211.1 - 3.3e-15 55.7 0.0 6.7e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KUM66211.1 - 7.2e-13 49.1 0.0 1.5e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KUM66211.1 - 8.3e-05 22.2 0.7 0.0011 18.6 0.5 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Zn_clus PF00172.13 KUM66212.1 - 2.5e-08 33.6 13.9 4.7e-08 32.7 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec63 PF02889.11 KUM66213.1 - 8.5e-45 153.3 0.0 2.2e-43 148.6 0.0 2.6 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 KUM66213.1 - 1.8e-17 62.8 0.5 3.9e-17 61.7 0.4 1.6 1 0 0 1 1 1 1 DnaJ domain 7tm_1 PF00001.16 KUM66213.1 - 0.011 14.8 0.0 0.024 13.7 0.0 1.5 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF4045 PF13254.1 KUM66214.1 - 1.6e-118 396.6 44.8 2.7e-72 244.3 14.6 6.2 5 3 4 9 9 9 2 Domain of unknown function (DUF4045) Gelsolin PF00626.17 KUM66214.1 - 2e-10 40.1 0.0 0.00097 18.7 0.0 3.6 3 0 0 3 3 3 3 Gelsolin repeat Spt5_N PF11942.3 KUM66215.1 - 0.25 11.9 4.6 0.35 11.5 3.2 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal adh_short_C2 PF13561.1 KUM66216.1 - 4.3e-28 98.7 1.1 5.2e-28 98.4 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KUM66216.1 - 6.8e-28 97.6 1.9 8.7e-28 97.3 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM66216.1 - 3.5e-14 52.8 1.1 4.8e-14 52.4 0.7 1.1 1 0 0 1 1 1 1 KR domain NAD_Gly3P_dh_N PF01210.18 KUM66216.1 - 0.0027 17.4 0.7 0.0055 16.4 0.5 1.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus THF_DHG_CYH_C PF02882.14 KUM66216.1 - 0.009 15.1 0.2 0.013 14.5 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 KUM66216.1 - 0.11 11.9 1.5 0.19 11.1 1.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_3 PF03447.11 KUM66216.1 - 0.11 12.8 0.4 0.22 11.9 0.2 1.5 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KUM66216.1 - 0.13 11.8 1.5 0.27 10.8 1.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Iso_dh PF00180.15 KUM66218.1 - 2.3e-131 437.8 0.0 2.6e-131 437.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Aldo_ket_red PF00248.16 KUM66219.1 - 2.1e-64 217.1 0.0 2.7e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1537 PF07005.6 KUM66219.1 - 1.6e-18 67.2 1.3 2.4e-17 63.3 0.9 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF1537 FMN_dh PF01070.13 KUM66220.1 - 2.2e-110 368.8 0.1 2.7e-110 368.5 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KUM66220.1 - 1.8e-05 23.8 0.1 3.8e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KUM66220.1 - 0.00024 20.0 0.5 0.00062 18.7 0.0 1.8 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 KUM66220.1 - 0.00078 18.5 1.7 0.028 13.4 0.0 2.6 2 1 0 3 3 3 1 Thiazole biosynthesis protein ThiG NMO PF03060.10 KUM66220.1 - 0.0013 18.0 1.7 0.0024 17.0 0.2 1.9 1 1 1 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.16 KUM66220.1 - 0.022 14.0 0.1 0.14 11.4 0.0 2.2 2 1 1 3 3 3 0 Histidine biosynthesis protein Dus PF01207.12 KUM66220.1 - 0.13 11.0 0.1 0.6 8.8 0.0 2.0 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Epimerase PF01370.16 KUM66221.1 - 9.8e-19 67.7 0.0 1.3e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KUM66221.1 - 4.7e-09 35.3 0.0 6.1e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KUM66221.1 - 4.8e-08 33.1 0.0 1.4e-07 31.5 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KUM66221.1 - 1e-07 31.1 0.0 0.00085 18.2 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain NAD_binding_4 PF07993.7 KUM66221.1 - 5.7e-07 28.7 0.0 0.0014 17.5 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein KR PF08659.5 KUM66221.1 - 2.2e-05 24.2 0.0 6.1e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KUM66221.1 - 0.00017 21.6 0.0 0.00029 20.9 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Ldh_1_N PF00056.18 KUM66221.1 - 0.0038 17.0 0.0 0.006 16.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KUM66221.1 - 0.05 12.5 0.0 0.15 10.9 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DapB_N PF01113.15 KUM66221.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Hydrophobin PF01185.13 KUM66222.1 - 3.8e-06 27.2 7.0 5.5e-06 26.7 4.9 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Granulin PF00396.13 KUM66222.1 - 0.051 13.6 1.8 0.051 13.6 1.3 2.3 2 0 0 2 2 2 0 Granulin Hydrophobin PF01185.13 KUM66223.1 - 0.00011 22.5 7.3 0.00017 21.9 5.1 1.3 1 0 0 1 1 1 1 Fungal hydrophobin CbiZ PF01955.13 KUM66223.1 - 0.03 14.1 0.2 0.046 13.5 0.1 1.3 1 0 0 1 1 1 0 Adenosylcobinamide amidohydrolase Granulin PF00396.13 KUM66223.1 - 0.06 13.4 2.1 0.06 13.4 1.5 2.3 2 0 0 2 2 2 0 Granulin TPP_enzyme_N PF02776.13 KUM66224.1 - 5.1e-29 100.9 0.0 7.9e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KUM66224.1 - 4.4e-17 62.1 0.0 1.3e-16 60.5 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KUM66224.1 - 7.2e-16 58.1 0.0 1.5e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain APC10 PF03256.11 KUM66225.1 - 6e-41 140.1 0.0 1.6e-40 138.8 0.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Flt3_lig PF02947.9 KUM66226.1 - 0.069 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 flt3 ligand Wzy_C PF04932.10 KUM66226.1 - 1.8 8.3 5.5 15 5.2 3.8 2.2 1 1 0 1 1 1 0 O-Antigen ligase bZIP_1 PF00170.16 KUM66227.1 - 6.8e-07 29.1 7.4 6.8e-06 25.9 3.4 2.2 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KUM66227.1 - 0.016 15.0 11.8 0.034 13.9 5.7 2.2 1 1 1 2 2 2 0 Basic region leucine zipper BicD PF09730.4 KUM66227.1 - 0.016 13.5 4.9 0.022 13.1 3.4 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D DUF4094 PF13334.1 KUM66227.1 - 0.035 14.5 2.8 0.087 13.2 2.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Lzipper-MIP1 PF14389.1 KUM66227.1 - 0.067 13.3 3.3 2.6 8.1 0.1 2.6 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Guanylate_kin PF00625.16 KUM66227.1 - 0.068 12.6 1.7 0.1 12.0 1.2 1.2 1 0 0 1 1 1 0 Guanylate kinase HALZ PF02183.13 KUM66227.1 - 0.11 12.1 0.2 2.7 7.7 0.0 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper DUF972 PF06156.8 KUM66227.1 - 0.16 12.3 2.2 0.24 11.7 1.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.10 KUM66227.1 - 0.22 11.0 4.5 0.67 9.4 0.9 2.2 1 1 1 2 2 2 0 Septum formation initiator EAP30 PF04157.11 KUM66227.1 - 0.24 10.5 4.0 0.37 9.9 2.8 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family DUF3573 PF12097.3 KUM66227.1 - 0.36 9.3 1.0 0.56 8.7 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF1192 PF06698.6 KUM66227.1 - 0.45 10.3 5.0 3.2 7.6 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1192) MbeD_MobD PF04899.7 KUM66227.1 - 0.62 9.9 6.1 2.7 7.9 0.1 3.0 2 1 1 3 3 3 0 MbeD/MobD like FlxA PF14282.1 KUM66227.1 - 4.1 7.3 9.8 0.29 11.0 3.1 1.9 2 0 0 2 2 2 0 FlxA-like protein Atg14 PF10186.4 KUM66227.1 - 5.7 5.7 7.9 8.9 5.1 5.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Acyl-CoA_dh_1 PF00441.19 KUM66228.1 - 1.9e-40 138.3 7.6 3.2e-40 137.6 5.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KUM66228.1 - 2.1e-26 92.6 2.3 8.8e-26 90.6 0.1 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KUM66228.1 - 6.3e-19 67.2 0.0 1.4e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KUM66228.1 - 1.4e-15 57.7 4.5 2.3e-15 57.0 3.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 KUM66228.1 - 0.014 14.8 0.1 0.044 13.1 0.1 1.8 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Chitin_synth_1 PF01644.12 KUM66228.1 - 0.12 12.1 0.3 1.4 8.6 0.1 2.3 2 0 0 2 2 2 0 Chitin synthase GWT1 PF06423.7 KUM66229.1 - 8.9e-42 142.4 3.0 8.9e-42 142.4 2.0 2.3 2 1 0 2 2 2 1 GWT1 DEAD PF00270.24 KUM66230.1 - 1.8e-38 131.6 0.0 2.7e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM66230.1 - 9.7e-22 76.6 0.0 8.2e-21 73.6 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KUM66230.1 - 0.0004 20.0 0.8 0.0012 18.5 0.1 2.2 2 1 1 3 3 3 1 Part of AAA domain ResIII PF04851.10 KUM66230.1 - 0.0055 16.5 0.0 0.0087 15.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 KUM66230.1 - 0.062 12.5 0.0 0.09 12.0 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain SecA_DEAD PF07517.9 KUM66230.1 - 0.076 12.2 0.0 0.16 11.2 0.0 1.7 1 1 0 1 1 1 0 SecA DEAD-like domain Helicase_RecD PF05127.9 KUM66230.1 - 0.08 12.5 0.0 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 Helicase p450 PF00067.17 KUM66231.1 - 2.9e-32 111.8 0.0 4e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Amidase PF01425.16 KUM66232.1 - 2.2e-88 297.0 0.1 2.9e-88 296.6 0.0 1.1 1 0 0 1 1 1 1 Amidase Cyt-b5 PF00173.23 KUM66233.1 - 1.3e-20 72.9 0.8 9.7e-20 70.1 0.1 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 KUM66233.1 - 6.7e-08 32.9 24.4 2.9e-07 30.8 16.3 2.0 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 KUM66233.1 - 0.028 14.4 0.2 0.061 13.3 0.2 1.5 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region DUF4117 PF13491.1 KUM66233.1 - 0.036 13.5 2.1 0.068 12.6 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4117) ATP_synt_I PF03899.10 KUM66233.1 - 0.073 13.2 4.4 0.55 10.4 0.1 2.2 2 0 0 2 2 2 0 ATP synthase I chain OMPdecase PF00215.19 KUM66234.1 - 6.9e-05 22.3 0.0 0.0002 20.8 0.0 1.7 2 0 0 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family PP2C PF00481.16 KUM66235.1 - 2.7e-32 112.1 0.0 1.7e-26 93.1 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 KUM66235.1 - 0.0052 16.2 0.0 0.0095 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C RRM_1 PF00076.17 KUM66236.1 - 2.3e-43 145.6 0.9 4.6e-22 77.4 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM66236.1 - 6.7e-34 115.6 0.1 3.4e-19 68.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 KUM66236.1 - 1.1e-28 99.3 0.1 2.7e-28 98.0 0.0 1.7 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 KUM66236.1 - 1.5e-20 72.7 0.0 7.7e-10 38.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KUM66236.1 - 0.0094 15.7 0.0 0.046 13.5 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif RNA_bind PF08675.6 KUM66236.1 - 0.084 12.8 0.0 0.73 9.8 0.0 2.4 3 0 0 3 3 3 0 RNA binding domain Adap_comp_sub PF00928.16 KUM66237.1 - 3e-16 59.3 0.0 4.8e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KUM66237.1 - 1.3e-07 31.4 0.1 2.1e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 KUM66237.1 - 0.0039 16.3 0.0 0.038 13.1 0.0 2.1 1 1 0 1 1 1 1 Muniscin C-terminal mu homology domain RPM2 PF08579.6 KUM66237.1 - 0.02 14.9 0.1 0.044 13.9 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) DUF3647 PF12363.3 KUM66237.1 - 0.053 13.6 0.8 0.1 12.7 0.5 1.5 1 0 0 1 1 1 0 Phage protein DUF2420 PF10336.4 KUM66238.1 - 1.7e-11 43.6 0.1 1.7e-11 43.6 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2420) Acetyltransf_4 PF13420.1 KUM66241.1 - 7.5e-06 25.9 0.0 3.2e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Arf PF00025.16 KUM66242.1 - 2.2e-65 219.1 1.7 2.5e-65 218.9 1.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KUM66242.1 - 3.5e-12 46.0 0.0 4e-12 45.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KUM66242.1 - 1.9e-11 43.5 0.0 2.4e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KUM66242.1 - 2.2e-11 43.0 4.0 2.8e-06 26.2 0.9 2.7 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 KUM66242.1 - 3.4e-08 33.4 0.0 4.4e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KUM66242.1 - 1.6e-07 30.9 0.0 2.8e-05 23.6 0.0 2.1 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KUM66242.1 - 1.7e-07 30.6 0.0 2.1e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KUM66242.1 - 3.5e-07 30.7 0.0 4.8e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein HCV_NS1 PF01560.12 KUM66242.1 - 0.0071 14.8 0.1 0.0084 14.6 0.0 1.1 1 0 0 1 1 1 1 Hepatitis C virus non-structural protein E2/NS1 NACHT PF05729.7 KUM66242.1 - 0.0096 15.5 0.3 0.2 11.3 0.1 2.1 2 0 0 2 2 2 1 NACHT domain cobW PF02492.14 KUM66242.1 - 0.013 14.9 0.1 0.74 9.2 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 KUM66242.1 - 0.015 16.1 0.1 0.029 15.1 0.1 1.4 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 KUM66242.1 - 0.066 12.4 0.3 0.21 10.8 0.2 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.4 KUM66242.1 - 0.072 12.5 0.1 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF3650 PF12368.3 KUM66242.1 - 0.091 12.2 0.2 0.091 12.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) AAA_18 PF13238.1 KUM66242.1 - 0.1 12.9 0.1 0.15 12.3 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KUM66242.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.20 KUM66243.1 - 9e-49 165.9 0.0 5e-46 156.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KUM66243.1 - 5.8e-32 110.7 0.0 1.9e-31 109.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM66243.1 - 0.00021 20.3 0.0 0.00032 19.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KUM66243.1 - 0.0021 16.9 0.1 0.0038 16.1 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 KUM66243.1 - 0.069 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KUM66243.1 - 0.18 10.5 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Meth_synt_2 PF01717.13 KUM66244.1 - 2e-10 40.1 0.0 7.1e-09 35.0 0.0 2.5 2 1 0 2 2 2 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KUM66244.1 - 0.0011 18.3 0.0 0.096 11.9 0.0 3.0 3 0 0 3 3 3 1 Cobalamin-independent synthase, N-terminal domain Pyr_redox_2 PF07992.9 KUM66245.1 - 6.9e-34 117.4 0.2 9.9e-34 116.9 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KUM66245.1 - 2.7e-32 111.0 0.1 5.2e-32 110.1 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KUM66245.1 - 5.6e-14 52.3 0.1 5.6e-14 52.3 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KUM66245.1 - 1.8e-05 24.8 0.1 0.00012 22.1 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KUM66245.1 - 0.00059 18.8 0.0 0.0011 17.9 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.13 KUM66245.1 - 0.042 13.5 0.1 0.042 13.5 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KUM66245.1 - 1.2 7.8 6.2 18 4.0 1.1 2.9 3 0 0 3 3 3 0 FAD binding domain Neurokinin_B PF03823.9 KUM66246.1 - 0.15 11.8 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 Neurokinin B Amidohydro_2 PF04909.9 KUM66247.1 - 1.1e-20 74.3 0.0 1.3e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Sugar_tr PF00083.19 KUM66248.1 - 6.2e-62 209.6 9.8 7.7e-55 186.2 4.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KUM66248.1 - 2e-05 23.4 24.0 0.00067 18.4 0.6 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Fungal_trans PF04082.13 KUM66249.1 - 8.9e-25 87.0 0.2 1.5e-24 86.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM66249.1 - 1.8e-10 40.5 8.5 3e-10 39.8 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.24 KUM66250.1 - 3.3e-43 147.0 0.0 9.4e-43 145.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KUM66250.1 - 1.5e-25 88.8 0.0 5.5e-25 87.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 KUM66250.1 - 3.1e-06 25.8 0.8 3.2e-05 22.5 0.1 2.8 1 1 0 2 2 2 1 Protein of unknown function (DUF1253) ResIII PF04851.10 KUM66250.1 - 0.076 12.8 0.0 0.076 12.8 0.0 4.3 4 1 0 4 4 4 0 Type III restriction enzyme, res subunit HEAT_EZ PF13513.1 KUM66251.1 - 1.1e-29 102.1 5.1 1.3e-13 51.0 0.0 9.9 9 2 4 13 13 12 3 HEAT-like repeat HEAT PF02985.17 KUM66251.1 - 2.8e-22 76.7 17.4 0.00019 21.2 0.1 11.3 13 0 0 13 13 13 6 HEAT repeat HEAT_2 PF13646.1 KUM66251.1 - 1.4e-21 76.5 1.4 5.1e-08 33.0 0.0 8.1 3 3 6 9 9 9 5 HEAT repeats Adaptin_N PF01602.15 KUM66251.1 - 2.8e-09 35.8 0.7 0.0012 17.2 0.0 3.4 3 2 0 3 3 3 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 KUM66251.1 - 5.1e-09 36.4 0.7 0.14 12.5 0.0 6.4 4 3 5 9 9 9 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 KUM66251.1 - 3.5e-07 30.2 4.2 0.011 15.6 0.1 6.0 7 1 0 7 7 7 1 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.14 KUM66251.1 - 5.8e-06 26.1 0.2 0.0079 16.0 0.0 4.4 3 1 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.3 KUM66251.1 - 6e-05 22.5 1.3 3.8 6.8 0.0 6.0 5 3 0 5 5 5 1 CLASP N terminal Arm PF00514.18 KUM66251.1 - 0.00012 21.8 3.4 0.6 10.0 0.0 5.9 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat RIX1 PF08167.7 KUM66251.1 - 0.00042 20.0 0.2 1.7 8.3 0.0 3.9 2 2 3 5 5 5 2 rRNA processing/ribosome biogenesis MMS19_C PF12460.3 KUM66251.1 - 0.0012 17.6 4.4 5.4 5.6 0.2 5.6 5 2 1 6 6 6 1 RNAPII transcription regulator C-terminal HEAT_PBS PF03130.11 KUM66251.1 - 0.0026 18.0 0.3 15 6.3 0.0 4.9 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat DUF1708 PF08101.6 KUM66251.1 - 0.043 12.6 0.0 0.084 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) DUF4612 PF15389.1 KUM66251.1 - 0.15 12.7 3.2 1.7 9.2 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4612) Sec7_N PF12783.2 KUM66251.1 - 0.17 11.2 1.8 3.6 6.9 0.1 3.3 3 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal plasmid_Toxin PF12703.2 KUM66252.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Toxin of toxin-antitoxin type 1 system Mg_trans_NIPA PF05653.9 KUM66253.1 - 1.2e-107 359.3 16.3 1.5e-107 359.0 11.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KUM66253.1 - 8.1e-05 22.7 6.4 8.1e-05 22.7 4.4 3.2 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 KUM66253.1 - 0.0004 20.4 9.0 0.0004 20.4 6.2 3.0 3 1 0 3 3 3 1 EamA-like transporter family DUF2937 PF11157.3 KUM66253.1 - 0.23 10.7 1.1 0.94 8.7 0.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) TrbC PF04956.8 KUM66253.1 - 1.6 8.7 8.5 0.23 11.4 2.0 2.4 2 0 0 2 2 2 0 TrbC/VIRB2 family Sugar_tr PF00083.19 KUM66254.1 - 9.5e-100 334.2 17.1 1.1e-99 334.0 11.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM66254.1 - 7.6e-23 80.7 19.0 7.6e-23 80.7 13.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily BNR_2 PF13088.1 KUM66255.1 - 3e-77 259.6 0.7 3.6e-77 259.3 0.5 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 KUM66255.1 - 0.00085 18.7 25.8 0.31 11.0 0.3 5.5 5 0 0 5 5 5 3 BNR/Asp-box repeat PSII_BNR PF14870.1 KUM66255.1 - 0.0016 17.4 1.8 0.013 14.4 0.0 2.6 3 1 0 3 3 3 1 Photosynthesis system II assembly factor YCF48 HIG_1_N PF04588.8 KUM66256.1 - 8.2e-07 28.6 1.0 1.2e-06 28.1 0.7 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF3683 PF12447.3 KUM66256.1 - 0.077 12.8 0.0 0.089 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3683) TRC8_N PF13705.1 KUM66256.1 - 0.09 11.3 0.0 0.11 11.0 0.0 1.0 1 0 0 1 1 1 0 TRC8 N-terminal domain Aldo_ket_red PF00248.16 KUM66257.1 - 8.4e-52 175.7 0.0 1e-51 175.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SPRY PF00622.23 KUM66258.1 - 3.2e-19 69.2 0.0 5.1e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Peptidase_M24 PF00557.19 KUM66259.1 - 4.7e-57 192.9 0.0 6.2e-57 192.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KUM66259.1 - 2.6e-26 91.6 0.0 5.4e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Terpene_synth_C PF03936.11 KUM66260.1 - 2.2e-06 27.0 0.5 2.2e-06 27.0 0.3 1.6 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain Peptidase_M15_4 PF13539.1 KUM66260.1 - 0.074 13.5 0.0 0.65 10.4 0.0 2.3 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase PDEase_II PF02112.10 KUM66261.1 - 9.4e-55 185.8 0.0 1.6e-26 93.0 0.0 3.0 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 KUM66261.1 - 1.9e-07 30.8 0.0 3.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KUM66261.1 - 2.1e-05 24.2 0.6 6e-05 22.7 0.4 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DHDPS PF00701.17 KUM66262.1 - 3.9e-44 150.3 0.0 5e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Zn_clus PF00172.13 KUM66263.1 - 6.1e-09 35.6 6.9 1.1e-08 34.8 4.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KUM66263.1 - 0.00034 19.5 0.2 0.00073 18.4 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain G3P_antiterm PF04309.7 KUM66263.1 - 0.21 10.5 0.1 0.51 9.3 0.0 1.6 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Fungal_trans PF04082.13 KUM66264.1 - 6.8e-26 90.6 0.2 1.4e-25 89.6 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM66264.1 - 2.9e-05 23.8 16.2 8e-05 22.4 11.2 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1880 PF08976.6 KUM66264.1 - 0.0046 17.0 0.9 0.014 15.4 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1880) Uds1 PF15456.1 KUM66266.1 - 1.7e-48 163.6 0.5 1.7e-48 163.6 0.3 8.2 4 2 3 8 8 8 1 Up-regulated During Septation IncA PF04156.9 KUM66266.1 - 0.0011 18.6 15.4 0.0011 18.6 10.7 7.5 3 2 4 7 7 7 2 IncA protein WEMBL PF05701.6 KUM66266.1 - 0.003 16.0 17.6 0.003 16.0 12.2 5.7 5 1 3 8 8 8 2 Weak chloroplast movement under blue light ADIP PF11559.3 KUM66266.1 - 0.0033 17.3 9.8 0.0033 17.3 6.8 9.2 3 2 9 12 12 12 2 Afadin- and alpha -actinin-Binding LPP PF04728.8 KUM66266.1 - 0.0097 15.6 1.0 0.0097 15.6 0.7 6.4 5 2 2 7 7 7 3 Lipoprotein leucine-zipper DUF1192 PF06698.6 KUM66266.1 - 0.062 13.1 0.0 0.062 13.1 0.0 7.6 7 1 1 8 8 8 0 Protein of unknown function (DUF1192) TPR_MLP1_2 PF07926.7 KUM66266.1 - 0.15 11.7 76.4 0.22 11.2 7.5 9.1 3 1 2 7 7 7 0 TPR/MLP1/MLP2-like protein Rab5-bind PF09311.6 KUM66266.1 - 2.1 8.1 86.0 0.2 11.5 18.6 6.4 2 1 4 6 6 6 0 Rabaptin-like protein Reo_sigmaC PF04582.7 KUM66266.1 - 4.1 6.4 26.5 0.62 9.1 3.9 4.3 1 1 3 4 4 4 0 Reovirus sigma C capsid protein HisKA PF00512.20 KUM66266.1 - 6.1 6.9 48.8 0.48 10.4 1.0 9.4 2 1 6 8 8 8 0 His Kinase A (phospho-acceptor) domain PH_10 PF15411.1 KUM66267.1 - 9.5e-40 135.4 0.0 2e-39 134.3 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 KUM66267.1 - 6.3e-34 115.8 0.0 1.3e-33 114.9 0.0 1.6 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.15 KUM66267.1 - 1.3e-29 103.3 3.8 2.4e-29 102.4 2.7 1.4 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.19 KUM66267.1 - 9.1e-08 31.6 0.1 2.2e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 PB1 domain WD40 PF00400.27 KUM66268.1 - 2.3e-38 128.6 11.3 1.3e-06 28.0 0.0 7.2 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 KUM66268.1 - 2.4e-10 39.9 1.0 4.8e-10 39.0 0.7 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KUM66268.1 - 3.2e-07 29.8 0.2 6.5e-07 28.8 0.2 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 KUM66268.1 - 1.1e-06 27.1 3.9 0.0061 14.7 0.0 3.3 2 1 0 3 3 3 2 Nucleoporin Nup120/160 zf-H2C2_2 PF13465.1 KUM66269.1 - 2.6e-16 59.0 29.8 1.1e-06 28.6 0.5 4.7 4 1 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 KUM66269.1 - 4.3e-16 58.1 39.7 0.00011 22.2 3.6 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KUM66269.1 - 1.9e-05 24.6 36.4 0.025 14.8 3.0 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger BLVR PF06375.6 KUM66269.1 - 0.025 14.3 3.1 0.05 13.4 2.2 1.4 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Spt5_N PF11942.3 KUM66269.1 - 0.29 11.7 6.9 0.56 10.8 4.8 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal PAT1 PF09770.4 KUM66269.1 - 0.39 8.8 44.6 0.46 8.6 30.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 KUM66269.1 - 0.82 9.4 25.7 1.1 9.1 17.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4129 PF13559.1 KUM66270.1 - 1.2e-05 25.2 0.2 3.4e-05 23.7 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) NICE-3 PF07406.6 KUM66270.1 - 0.0042 16.6 0.0 0.23 10.9 0.0 2.1 2 0 0 2 2 2 2 NICE-3 protein Suc_Fer-like PF06999.7 KUM66271.1 - 2.8e-36 125.7 0.0 4.7e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Sucrase/ferredoxin-like NTP_transferase PF00483.18 KUM66272.1 - 4.6e-49 166.9 0.0 9.2e-49 165.9 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 KUM66272.1 - 5.2e-13 47.8 11.9 4.7e-10 38.5 2.9 4.4 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KUM66272.1 - 1.9e-10 41.0 0.0 3.1e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 KUM66272.1 - 7.8e-07 28.5 3.0 7.8e-07 28.5 2.1 3.1 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase IspD PF01128.14 KUM66272.1 - 0.15 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase adh_short PF00106.20 KUM66273.1 - 1.5e-07 31.5 0.1 3.9e-05 23.6 0.0 2.8 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KUM66273.1 - 0.016 14.8 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 KR domain CoA_transf_3 PF02515.12 KUM66273.1 - 0.053 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 CoA-transferase family III Peptidase_M41 PF01434.13 KUM66275.1 - 3.6e-66 222.6 0.4 6.7e-66 221.8 0.3 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KUM66275.1 - 6.6e-43 146.0 0.0 2.1e-42 144.4 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KUM66275.1 - 1.1e-05 26.2 0.1 3.9e-05 24.4 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.9 KUM66275.1 - 1.1e-05 25.1 0.0 3.3e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KUM66275.1 - 1.4e-05 25.1 0.0 5.9e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.8 KUM66275.1 - 0.00012 20.9 0.0 0.00012 20.9 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus AAA_22 PF13401.1 KUM66275.1 - 0.00014 21.9 0.1 0.016 15.3 0.1 2.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KUM66275.1 - 0.00055 19.0 0.0 0.0011 18.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KUM66275.1 - 0.0017 18.0 0.3 0.0047 16.6 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 KUM66275.1 - 0.0018 17.7 1.4 0.11 11.9 0.3 2.5 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 KUM66275.1 - 0.0021 17.9 0.0 0.0062 16.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KUM66275.1 - 0.0027 17.1 0.0 0.0055 16.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 KUM66275.1 - 0.0079 15.3 1.6 0.021 13.8 0.2 2.3 2 1 0 2 2 2 1 Zeta toxin AAA_28 PF13521.1 KUM66275.1 - 0.017 15.0 0.0 0.043 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KUM66275.1 - 0.019 14.1 0.1 0.039 13.1 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 KUM66275.1 - 0.023 14.6 0.0 0.079 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 KUM66275.1 - 0.027 14.3 0.0 0.064 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KUM66275.1 - 0.044 13.4 0.3 1.1 8.8 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 KUM66275.1 - 0.05 13.8 0.0 0.16 12.2 0.0 2.0 2 0 0 2 2 1 0 AAA domain KaiC PF06745.8 KUM66275.1 - 0.083 11.9 0.4 1.2 8.1 0.0 2.5 3 0 0 3 3 3 0 KaiC MFS_1 PF07690.11 KUM66276.1 - 0.0067 15.1 0.5 0.0094 14.6 0.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily FBPase PF00316.15 KUM66277.1 - 4.5e-117 390.4 0.0 5.2e-117 390.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Sugar_tr PF00083.19 KUM66278.1 - 1.4e-28 99.6 28.1 6e-17 61.3 6.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KUM66278.1 - 3.5e-20 72.0 41.4 3.5e-10 39.1 12.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C2H2_4 PF13894.1 KUM66280.1 - 0.0049 17.1 9.6 2.4 8.6 0.2 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KUM66280.1 - 0.036 14.4 9.8 0.082 13.2 0.1 3.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type SNF2_N PF00176.18 KUM66281.1 - 3e-35 121.4 0.0 4.2e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KUM66281.1 - 4.7e-11 42.4 0.0 9.7e-11 41.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1162 PF06650.7 KUM66282.1 - 2.9e-88 295.6 0.0 1.1e-86 290.5 0.0 3.3 3 1 1 4 4 4 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 KUM66282.1 - 2.2e-42 143.3 0.0 6.7e-42 141.7 0.0 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 KUM66282.1 - 5.1e-06 26.5 0.2 3.1e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 ATG C terminal domain Urease_beta PF00699.15 KUM66282.1 - 0.093 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Urease beta subunit BA14K PF07886.6 KUM66282.1 - 1.4 8.6 1.1 3 7.6 0.8 1.5 1 0 0 1 1 1 0 BA14K-like protein Pyr_redox_3 PF13738.1 KUM66283.1 - 9.6e-24 84.5 0.0 1.2e-23 84.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM66283.1 - 5.7e-11 42.2 0.0 3.1e-10 39.9 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 KUM66283.1 - 4.1e-10 38.4 0.5 2.4e-09 35.9 0.4 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KUM66283.1 - 1.8e-07 30.3 0.2 0.00011 21.2 0.0 2.0 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KUM66283.1 - 7.8e-07 29.1 0.0 1.9e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM66283.1 - 2.6e-05 24.0 0.1 0.00012 21.9 0.0 2.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 KUM66283.1 - 0.00025 20.0 0.0 0.0004 19.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KUM66283.1 - 0.0022 18.3 0.2 0.28 11.6 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase CoA_binding PF02629.14 KUM66283.1 - 0.085 13.3 0.0 2.7 8.5 0.0 2.3 2 0 0 2 2 2 0 CoA binding domain AlaDh_PNT_C PF01262.16 KUM66283.1 - 0.089 12.3 0.0 0.33 10.5 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Malic_M PF03949.10 KUM66283.1 - 0.15 11.6 0.1 7.2 6.0 0.0 2.6 3 0 0 3 3 3 0 Malic enzyme, NAD binding domain Aldo_ket_red PF00248.16 KUM66285.1 - 5.6e-70 235.3 0.0 6.7e-70 235.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans_2 PF11951.3 KUM66287.1 - 3.8e-08 32.3 0.1 6.2e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM66287.1 - 7.6e-05 22.5 0.8 0.00017 21.4 0.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.1 KUM66289.1 - 2.2e-62 210.9 45.4 2.8e-62 210.6 31.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM66289.1 - 4.7e-20 71.3 36.3 6.3e-20 70.9 25.1 1.0 1 0 0 1 1 1 1 Amino acid permease Myosin_TH1 PF06017.8 KUM66289.1 - 0.17 11.1 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Myosin tail Oxidored_FMN PF00724.15 KUM66291.1 - 3.4e-75 253.1 0.0 4.9e-75 252.6 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1848 PF08902.6 KUM66291.1 - 0.066 12.7 0.0 0.098 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Fungal_trans PF04082.13 KUM66293.1 - 1.6e-05 23.9 0.6 1.6e-05 23.9 0.4 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pectate_lyase PF03211.8 KUM66294.1 - 1.2e-61 207.8 4.0 1.6e-61 207.4 2.8 1.0 1 0 0 1 1 1 1 Pectate lyase MFS_1 PF07690.11 KUM66295.1 - 7.5e-14 51.2 6.3 1.2e-13 50.5 4.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KUM66295.1 - 0.00011 21.9 3.3 0.0014 18.3 2.3 2.5 1 1 0 1 1 1 1 MFS_1 like family FGGY_C PF02782.11 KUM66296.1 - 4.1e-72 241.9 1.6 7.2e-72 241.1 1.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KUM66296.1 - 2.3e-62 210.4 0.0 3.1e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 KUM66296.1 - 0.027 13.7 0.3 4 6.6 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DUF3429 PF11911.3 KUM66297.1 - 5.1e-40 136.7 11.7 1.2e-39 135.5 8.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) DUF3405 PF11885.3 KUM66298.1 - 1.2e-168 561.4 0.3 1.2e-168 561.4 0.2 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3405) DUF1376 PF07120.6 KUM66298.1 - 0.077 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1376) MFS_1 PF07690.11 KUM66301.1 - 7.5e-25 87.3 30.9 7.5e-25 87.3 21.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2929 PF11151.3 KUM66301.1 - 0.87 9.7 6.1 2.1 8.4 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2929) UCR_hinge PF02320.11 KUM66302.1 - 1.2e-25 89.2 6.5 2.5e-25 88.1 4.5 1.6 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Mitofilin PF09731.4 KUM66302.1 - 0.37 9.3 19.4 0.44 9.1 13.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein RR_TM4-6 PF06459.7 KUM66302.1 - 0.4 10.5 20.3 0.45 10.3 14.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spore_coat_CotO PF14153.1 KUM66302.1 - 0.46 9.8 20.3 0.61 9.4 14.1 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Pneumo_att_G PF05539.6 KUM66302.1 - 0.79 9.0 5.8 0.96 8.7 4.0 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DHHW PF14286.1 KUM66302.1 - 0.82 8.9 10.2 1 8.6 7.1 1.1 1 0 0 1 1 1 0 DHHW protein DUF4045 PF13254.1 KUM66302.1 - 0.95 8.6 14.3 1.1 8.4 9.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CENP-T PF15511.1 KUM66302.1 - 1.2 8.2 22.6 1.4 8.0 15.7 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF1510 PF07423.6 KUM66302.1 - 1.5 8.1 25.2 2 7.7 17.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SAPS PF04499.10 KUM66302.1 - 1.6 7.2 10.6 1.7 7.2 7.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC27 PF09507.5 KUM66302.1 - 2.6 7.1 23.7 2.9 7.0 16.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Raftlin PF15250.1 KUM66302.1 - 4.4 5.7 8.6 5 5.5 6.0 1.1 1 0 0 1 1 1 0 Raftlin Nop14 PF04147.7 KUM66302.1 - 5.4 4.8 23.5 5.6 4.7 16.3 1.1 1 0 0 1 1 1 0 Nop14-like family CT47 PF15623.1 KUM66302.1 - 6.3 6.4 39.1 8.6 6.0 27.1 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 Hid1 PF12722.2 KUM66302.1 - 7.7 4.0 12.2 9 3.8 8.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Prenyltransf PF01255.14 KUM66303.1 - 7.7e-82 273.7 0.0 1.3e-81 272.9 0.0 1.3 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF566 PF04484.7 KUM66303.1 - 0.29 10.6 2.2 0.42 10.0 1.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Acyltransferase PF01553.16 KUM66304.1 - 8.1e-10 38.2 0.0 0.00069 19.0 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase Aha1_N PF09229.6 KUM66305.1 - 1.4e-37 128.5 0.4 2.3e-37 127.8 0.2 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 KUM66305.1 - 4.7e-16 59.0 1.5 6.4e-16 58.5 0.2 1.8 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Saccharop_dh PF03435.13 KUM66306.1 - 3.2e-129 431.3 0.0 3.6e-129 431.1 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 KUM66306.1 - 1.3e-08 35.0 0.9 7.6e-07 29.3 0.3 2.3 2 0 0 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 KUM66306.1 - 2.2e-08 34.3 0.2 3.6e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 KUM66306.1 - 0.00027 20.2 0.5 0.00043 19.6 0.3 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 KUM66306.1 - 0.0004 19.1 0.1 0.00059 18.6 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family IlvN PF07991.7 KUM66306.1 - 0.00097 18.5 0.2 0.01 15.2 0.1 2.4 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 KUM66306.1 - 0.0019 18.5 0.2 0.0043 17.4 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 KUM66306.1 - 0.014 15.6 0.3 0.028 14.6 0.2 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Semialdhyde_dh PF01118.19 KUM66306.1 - 0.058 13.6 0.2 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Beta_elim_lyase PF01212.16 KUM66309.1 - 1.2e-42 146.0 0.0 1.5e-42 145.7 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KUM66309.1 - 7.3e-06 25.1 0.0 1.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Pyridoxal_deC PF00282.14 KUM66309.1 - 0.0047 15.4 0.1 0.0096 14.4 0.0 1.5 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_3 PF00202.16 KUM66309.1 - 0.0051 15.7 0.1 0.2 10.4 0.1 2.2 2 0 0 2 2 2 2 Aminotransferase class-III Arylsulfotran_2 PF14269.1 KUM66310.1 - 2e-42 145.4 0.9 2.9e-42 144.8 0.6 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KUM66310.1 - 1.7e-12 46.6 1.9 2.6e-11 42.7 1.3 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) NAD_binding_4 PF07993.7 KUM66312.1 - 4.4e-72 242.0 0.0 6.8e-72 241.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KUM66312.1 - 1.2e-71 241.2 0.0 2.1e-71 240.5 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KUM66312.1 - 1.2e-12 47.7 0.0 2.9e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KUM66312.1 - 3.8e-10 39.8 0.0 9.3e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KUM66312.1 - 2.7e-09 37.8 0.0 1.6e-08 35.3 0.0 2.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 KUM66312.1 - 7.7e-06 24.8 0.0 1.8e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KUM66312.1 - 0.00064 19.7 0.0 0.02 14.8 0.0 2.7 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KUM66312.1 - 0.0024 16.7 0.0 0.051 12.4 0.0 2.4 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KUM66312.1 - 0.045 12.6 0.0 0.076 11.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.20 KUM66312.1 - 0.075 12.9 1.5 0.3 10.9 0.2 2.7 2 1 0 2 2 2 0 short chain dehydrogenase Semialdhyde_dh PF01118.19 KUM66312.1 - 0.14 12.4 0.1 2.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Sulfatase PF00884.18 KUM66314.1 - 5e-15 55.4 0.2 8.1e-15 54.7 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KUM66314.1 - 0.0001 21.7 0.1 0.00017 21.0 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KUM66314.1 - 0.033 12.6 0.3 0.052 11.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF1501 PF07394.7 KUM66314.1 - 0.074 11.8 2.3 0.059 12.2 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1501) AAA PF00004.24 KUM66315.1 - 1.9e-17 63.6 0.0 4.2e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KUM66315.1 - 0.0074 16.4 0.1 0.073 13.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KUM66315.1 - 0.019 15.7 0.0 0.087 13.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KUM66315.1 - 0.024 14.3 0.0 0.057 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KUM66315.1 - 0.051 12.6 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus KaiC PF06745.8 KUM66315.1 - 0.094 11.8 0.3 1.2 8.1 0.1 2.2 1 1 1 2 2 2 0 KaiC PIG-S PF10510.4 KUM66315.1 - 0.098 11.3 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein AAA_19 PF13245.1 KUM66315.1 - 0.19 11.5 0.1 0.83 9.4 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain Mannosyl_trans2 PF04188.8 KUM66316.1 - 1.9e-62 211.6 11.4 2.1e-61 208.1 7.9 1.9 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) DUF3437 PF11919.3 KUM66317.1 - 4.3e-32 109.6 0.0 1.4e-31 108.0 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) CLASP_N PF12348.3 KUM66317.1 - 0.00012 21.4 0.4 0.28 10.5 0.0 3.1 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 KUM66317.1 - 0.0018 18.1 0.9 0.71 10.1 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat Aminotran_1_2 PF00155.16 KUM66319.1 - 4.1e-34 118.1 0.0 5.3e-34 117.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Fer2_2 PF01799.15 KUM66320.1 - 6.4e-11 41.9 0.3 1.4e-10 40.9 0.2 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 KUM66320.1 - 3.3e-09 36.3 0.9 1.7e-08 34.0 0.1 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_BFD PF04324.10 KUM66320.1 - 0.21 11.6 1.8 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain WWbp PF10349.4 KUM66321.1 - 2.7e-22 79.8 1.3 8.7e-22 78.1 0.3 1.9 2 0 0 2 2 2 1 WW-domain ligand protein Vps36_ESCRT-II PF11605.3 KUM66321.1 - 0.00011 21.9 0.0 0.014 15.1 0.0 2.3 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 Mito_carr PF00153.22 KUM66322.1 - 5.6e-46 154.1 7.9 4.4e-17 61.5 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3602 PF12223.3 KUM66324.1 - 2.2e-13 50.3 15.5 5.3e-10 39.5 3.2 3.0 1 1 3 4 4 4 4 Protein of unknown function (DUF3602) MFS_1 PF07690.11 KUM66326.1 - 5.9e-50 169.9 69.1 3.2e-31 108.3 15.2 2.6 3 0 0 3 3 3 2 Major Facilitator Superfamily UNC-93 PF05978.11 KUM66326.1 - 9.5e-08 31.6 3.9 9.5e-08 31.6 2.7 3.5 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 zf-LITAF-like PF10601.4 KUM66326.1 - 0.066 13.0 0.2 10 6.0 0.1 3.4 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain DUF2406 PF10295.4 KUM66327.1 - 2.7e-20 72.6 0.1 2.7e-20 72.6 0.0 3.0 3 0 0 3 3 3 1 Uncharacterised protein (DUF2406) Glyco_tranf_2_3 PF13641.1 KUM66328.1 - 1.1e-39 136.5 0.0 1.6e-39 136.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KUM66328.1 - 2.7e-21 76.1 1.8 2.7e-21 76.1 1.3 3.0 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.9 KUM66328.1 - 5.1e-14 51.5 5.7 4.7e-10 38.4 0.3 2.9 2 1 2 4 4 4 2 Cellulose synthase Glycos_transf_2 PF00535.21 KUM66328.1 - 2.1e-12 47.0 0.0 3.5e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KUM66328.1 - 1.3e-11 44.0 0.0 2.4e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.10 KUM66328.1 - 0.00078 17.9 0.2 0.0078 14.6 0.0 2.2 2 0 0 2 2 2 1 Chitin synthase Glyco_hydro_12 PF01670.11 KUM66329.1 - 7.6e-16 58.2 2.5 1.6e-15 57.2 1.8 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Zn_clus PF00172.13 KUM66330.1 - 2e-08 33.9 10.9 4e-08 33.0 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_capsid PF06112.6 KUM66330.1 - 2.6 8.0 6.1 0.37 10.8 0.2 2.5 2 1 1 3 3 3 0 Gammaherpesvirus capsid protein Ring_hydroxyl_A PF00848.14 KUM66331.1 - 1.1e-41 142.8 5.1 2.2e-41 141.7 3.5 1.5 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) CorC_HlyC PF03471.12 KUM66331.1 - 0.0048 16.6 0.0 0.076 12.7 0.0 2.7 3 0 0 3 3 3 1 Transporter associated domain DIPSY PF11763.3 KUM66331.1 - 0.0098 15.6 1.7 0.033 13.9 0.0 2.5 2 1 1 3 3 3 1 Cell-wall adhesin ligand-binding C-terminal Fungal_trans PF04082.13 KUM66333.1 - 8e-09 34.7 0.1 1.6e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM66333.1 - 2.2e-07 30.6 9.8 2.2e-07 30.6 6.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ras PF00071.17 KUM66335.1 - 5e-55 185.2 0.0 5.8e-55 185.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KUM66335.1 - 1e-17 64.7 0.0 1.4e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KUM66335.1 - 5.4e-08 32.2 0.0 6.9e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MAM1 PF10434.4 KUM66335.1 - 0.11 11.6 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Monopolin complex protein MAM1 RRM_1 PF00076.17 KUM66336.1 - 5.4e-13 48.3 0.0 1.2e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM66336.1 - 2.3e-09 37.0 0.0 4.9e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM66336.1 - 0.084 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CMS1 PF14617.1 KUM66337.1 - 1.4e-80 269.9 4.8 1.9e-80 269.5 3.3 1.2 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 KUM66337.1 - 0.00013 21.4 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase CENP-T PF15511.1 KUM66338.1 - 6.9e-12 45.3 3.3 6.9e-12 45.3 2.3 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T CENP-T PF15511.1 KUM66339.1 - 9.2e-55 186.5 8.6 1.6e-54 185.7 6.0 1.4 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 KUM66339.1 - 2.1e-08 34.2 0.0 3.6e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 KUM66339.1 - 0.0014 18.7 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KUM66339.1 - 0.059 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone MBA1 PF07961.6 KUM66340.1 - 1.7e-06 27.0 0.0 2.5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.10 KUM66340.1 - 0.05 13.5 0.1 0.12 12.2 0.1 1.7 1 1 0 1 1 1 0 Tim44-like domain RhoGAP PF00620.22 KUM66341.1 - 1.1e-32 112.7 0.0 3.8e-32 111.0 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 KUM66341.1 - 4.8e-14 52.3 0.3 1.6e-13 50.6 0.2 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Flagellin_N PF00669.15 KUM66341.1 - 0.76 9.5 6.1 3.7 7.3 0.1 2.8 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region WD40 PF00400.27 KUM66342.1 - 6.9e-38 127.1 7.0 1.3e-07 31.1 0.0 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KUM66342.1 - 5.3e-09 36.0 0.1 0.003 17.3 0.0 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A ATPgrasp_ST PF14397.1 KUM66342.1 - 0.033 13.2 0.0 0.049 12.7 0.0 1.1 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp E3_binding PF02817.12 KUM66343.1 - 1.3e-07 31.0 0.2 1.3e-07 31.0 0.1 2.7 3 0 0 3 3 3 1 e3 binding domain DUF3235 PF11574.3 KUM66343.1 - 0.32 11.2 3.8 0.26 11.5 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) Glyco_hydro_62 PF03664.8 KUM66344.1 - 5.3e-138 458.6 10.0 6.1e-138 458.4 6.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 PepSY_TM_1 PF13172.1 KUM66345.1 - 0.17 11.7 2.2 0.34 10.7 0.2 2.2 2 0 0 2 2 2 0 PepSY-associated TM helix DUF2841 PF11001.3 KUM66346.1 - 5.6e-45 152.2 0.0 8.2e-45 151.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF2838 PF10998.3 KUM66347.1 - 2.8e-44 149.5 10.4 2.8e-44 149.5 7.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Atg14 PF10186.4 KUM66347.1 - 0.0032 16.4 4.5 0.0056 15.6 3.1 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF3106 PF11304.3 KUM66347.1 - 0.016 15.5 4.8 0.043 14.2 3.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) CcmD PF04995.9 KUM66348.1 - 0.23 11.1 1.3 0.49 10.1 0.1 2.1 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) SMC_N PF02463.14 KUM66349.1 - 1.4e-52 178.0 21.9 5.9e-51 172.7 15.2 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KUM66349.1 - 2.3e-31 108.2 0.0 9.9e-31 106.2 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KUM66349.1 - 1.9e-12 47.7 10.3 1.2e-06 28.6 0.0 4.2 3 2 1 4 4 4 2 AAA domain AAA_29 PF13555.1 KUM66349.1 - 3.5e-08 32.8 0.0 8.4e-08 31.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain MAD PF05557.8 KUM66349.1 - 1.9e-05 22.9 28.9 1.9e-05 22.9 20.0 4.1 3 1 1 4 4 4 2 Mitotic checkpoint protein Reo_sigmaC PF04582.7 KUM66349.1 - 2.4e-05 23.7 18.1 0.5 9.4 0.0 4.7 5 0 0 5 5 5 4 Reovirus sigma C capsid protein DUF4200 PF13863.1 KUM66349.1 - 0.0002 21.2 5.4 0.0002 21.2 3.7 8.3 4 2 4 8 8 5 2 Domain of unknown function (DUF4200) SbcCD_C PF13558.1 KUM66349.1 - 0.0011 18.8 0.0 0.0066 16.3 0.0 2.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit IncA PF04156.9 KUM66349.1 - 0.0054 16.3 12.9 0.0054 16.3 9.0 7.1 3 2 3 6 6 4 2 IncA protein TPR_MLP1_2 PF07926.7 KUM66349.1 - 0.018 14.7 0.2 0.018 14.7 0.1 7.4 5 2 2 7 7 7 0 TPR/MLP1/MLP2-like protein AAA_23 PF13476.1 KUM66349.1 - 0.7 10.1 113.3 4.4e+02 1.0 41.3 6.6 3 2 0 3 3 2 0 AAA domain ABC_tran PF00005.22 KUM66349.1 - 0.9 9.8 0.0 0.9 9.8 0.0 6.6 4 2 2 6 6 6 0 ABC transporter AAA_22 PF13401.1 KUM66349.1 - 1 9.4 6.7 7 6.7 0.0 4.8 5 1 0 5 5 5 0 AAA domain AAA_13 PF13166.1 KUM66349.1 - 5.6 5.3 96.8 0.1 11.0 11.4 6.1 3 2 2 5 5 5 0 AAA domain DUF1675 PF07897.6 KUM66350.1 - 1.4 8.6 10.1 2 8.2 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Glyco_hydro_10 PF00331.15 KUM66351.1 - 5.1e-96 321.4 0.0 6.3e-75 252.1 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 10 SNF2_N PF00176.18 KUM66352.1 - 4.5e-61 206.2 0.5 4.5e-61 206.2 0.4 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KUM66352.1 - 2.7e-15 55.9 0.0 9.1e-15 54.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KUM66352.1 - 1e-06 28.7 0.2 3.4e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KUM66352.1 - 8.7e-06 25.3 0.0 1.9e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HHH_3 PF12836.2 KUM66352.1 - 0.056 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif VMA21 PF09446.5 KUM66353.1 - 5.4e-20 71.0 6.8 7.3e-20 70.6 4.7 1.2 1 0 0 1 1 1 1 VMA21-like domain Pyrophosphatase PF00719.14 KUM66354.1 - 6.8e-51 171.7 0.2 8.8e-51 171.4 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Dus PF01207.12 KUM66355.1 - 8.4e-45 152.9 0.0 1.9e-44 151.7 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Sec20 PF03908.8 KUM66356.1 - 9.6e-16 57.2 1.1 3.7e-15 55.4 0.7 2.1 1 0 0 1 1 1 1 Sec20 RHD3 PF05879.7 KUM66356.1 - 0.0058 14.6 0.3 0.011 13.6 0.0 1.5 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) V-SNARE PF05008.10 KUM66356.1 - 0.066 13.3 5.7 0.15 12.2 0.7 3.3 3 1 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Syntaxin-6_N PF09177.6 KUM66356.1 - 0.48 10.8 5.3 1.3 9.4 0.2 3.1 2 1 0 2 2 2 0 Syntaxin 6, N-terminal MRP_L53 PF10780.4 KUM66357.1 - 6.5e-19 67.6 0.0 9.4e-19 67.1 0.0 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Zn_clus PF00172.13 KUM66358.1 - 1.4e-07 31.2 8.1 2.8e-07 30.3 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KUM66358.1 - 3.5e-06 25.8 0.2 6.2e-05 21.7 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain AAA PF00004.24 KUM66359.1 - 4.4e-15 56.0 0.0 2e-14 53.9 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KUM66359.1 - 1.3e-12 47.7 0.0 3.1e-11 43.1 0.0 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 KUM66359.1 - 1.3e-10 41.1 0.0 3.5e-10 39.7 0.0 1.8 1 1 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 KUM66359.1 - 1.6e-10 40.3 0.0 4.6e-08 32.1 0.0 2.2 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 KUM66359.1 - 2.3e-06 26.8 0.0 8.6e-06 24.9 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KUM66359.1 - 3.8e-06 27.0 0.0 2.1e-05 24.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KUM66359.1 - 7.4e-05 22.4 0.0 0.0002 21.0 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KUM66359.1 - 8.9e-05 22.5 0.1 0.0021 18.0 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_11 PF13086.1 KUM66359.1 - 0.00014 21.4 0.0 0.00027 20.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KUM66359.1 - 0.00017 20.8 0.0 0.011 14.9 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 KUM66359.1 - 0.00032 20.5 0.0 0.00067 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KUM66359.1 - 0.00099 18.7 0.8 0.0044 16.6 0.2 2.2 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 KUM66359.1 - 0.0026 16.7 0.0 0.0044 16.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 KUM66359.1 - 0.0051 16.3 0.0 0.015 14.7 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_5 PF07728.9 KUM66359.1 - 0.0056 16.4 0.1 0.041 13.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KUM66359.1 - 0.012 15.0 0.1 0.037 13.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 KUM66359.1 - 0.013 14.4 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DNA_pol3_delta PF06144.8 KUM66359.1 - 0.026 14.0 0.0 0.051 13.0 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_17 PF13207.1 KUM66359.1 - 0.027 15.3 0.0 0.055 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KUM66359.1 - 0.03 14.6 0.0 0.042 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KUM66359.1 - 0.049 13.0 0.1 0.66 9.3 0.0 2.2 1 1 1 2 2 2 0 AAA-like domain AAA_28 PF13521.1 KUM66359.1 - 0.057 13.3 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KUM66359.1 - 0.085 12.7 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KUM66359.1 - 0.089 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KUM66359.1 - 0.1 12.2 0.0 2.5 7.7 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MFS_1 PF07690.11 KUM66360.1 - 8e-09 34.6 28.6 9.5e-09 34.4 19.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM66360.1 - 0.0014 17.3 17.5 0.0017 17.0 12.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 KUM66360.1 - 0.083 12.6 0.3 0.083 12.6 0.2 3.1 2 1 1 3 3 3 0 MFS_1 like family Med12 PF09497.5 KUM66361.1 - 4.6e-27 93.7 0.4 1.2e-26 92.4 0.3 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 ACDC PF14733.1 KUM66361.1 - 0.059 13.4 0.0 13 5.9 0.0 2.8 2 0 0 2 2 2 0 AP2-coincident C-terminal RRM_1 PF00076.17 KUM66362.1 - 2.4e-11 43.1 0.1 2e-07 30.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM66362.1 - 1.1e-07 31.7 0.1 1.8e-05 24.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM66362.1 - 0.011 15.5 0.1 0.5 10.2 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CIA30 PF08547.7 KUM66363.1 - 3.7e-38 130.8 0.1 5e-24 84.9 0.0 2.2 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) Cation_ATPase_N PF00690.21 KUM66363.1 - 0.07 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus SAICAR_synt PF01259.13 KUM66364.1 - 1.6e-87 292.7 0.0 1.9e-87 292.5 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase EOS1 PF12326.3 KUM66365.1 - 2.5e-31 108.3 15.1 3.3e-26 91.7 6.2 2.1 1 1 1 2 2 2 2 N-glycosylation protein SUI1 PF01253.17 KUM66366.1 - 1.6e-29 101.5 5.8 2.1e-29 101.1 4.0 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cas_Csa5 PF09702.5 KUM66366.1 - 0.1 12.7 0.7 0.33 11.0 0.1 1.8 1 1 0 2 2 2 0 CRISPR-associated protein (Cas_Csa5) UPF0139 PF03669.8 KUM66368.1 - 0.0026 17.2 1.2 0.0037 16.7 0.8 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) CbiM PF01891.11 KUM66368.1 - 0.094 12.3 0.1 0.12 11.9 0.1 1.1 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region Apc5 PF12862.2 KUM66369.1 - 7e-32 109.1 6.1 2.2e-31 107.5 4.2 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 TPR_19 PF14559.1 KUM66369.1 - 0.00075 19.7 0.0 3.1 8.2 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KUM66369.1 - 0.043 13.5 2.4 4.5 7.2 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KUM66369.1 - 0.12 12.3 8.2 10 6.1 0.1 5.1 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 KUM66369.1 - 0.28 11.1 2.1 1.4 8.9 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat CLP_protease PF00574.18 KUM66371.1 - 1e-73 246.9 0.0 1.3e-73 246.5 0.0 1.1 1 0 0 1 1 1 1 Clp protease adh_short PF00106.20 KUM66374.1 - 4.5e-18 65.7 0.2 3.6e-17 62.7 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KUM66374.1 - 3.8e-10 39.7 0.0 1.6e-09 37.7 0.0 1.9 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 KUM66374.1 - 5.5e-05 22.2 0.1 0.00014 20.8 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Glyco_tran_WecB PF03808.8 KUM66374.1 - 0.00055 19.3 0.0 0.6 9.4 0.0 2.5 2 1 0 2 2 2 2 Glycosyl transferase WecB/TagA/CpsF family adh_short_C2 PF13561.1 KUM66374.1 - 0.0015 18.3 0.0 0.0027 17.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 KUM66374.1 - 0.0017 18.4 0.0 0.0031 17.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 KUM66374.1 - 0.0025 17.2 0.0 0.0063 15.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Lipoprotein_18 PF06804.6 KUM66374.1 - 0.021 13.5 0.0 0.033 12.9 0.0 1.2 1 0 0 1 1 1 0 NlpB/DapX lipoprotein SURF1 PF02104.10 KUM66375.1 - 2.9e-56 190.6 0.0 3.9e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 SURF1 family Sas10_Utp3 PF04000.10 KUM66376.1 - 2e-18 66.3 0.8 2e-18 66.3 0.6 1.9 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Hid1 PF12722.2 KUM66376.1 - 3.5 5.1 10.1 4.2 4.9 7.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GAGA_bind PF06217.7 KUM66376.1 - 5.9 6.7 14.2 7.4 6.4 9.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2076 PF09849.4 KUM66377.1 - 9.2e-09 35.7 12.4 1.1e-08 35.4 8.6 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 KUM66377.1 - 4.3e-05 23.2 0.8 7.4e-05 22.5 0.5 1.5 1 0 0 1 1 1 1 CHCH domain Gly-zipper_OmpA PF13436.1 KUM66377.1 - 0.8 9.3 11.2 1.2 8.7 7.6 1.5 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain SET PF00856.23 KUM66378.1 - 6.6e-19 68.7 0.0 1.2e-18 67.8 0.0 1.5 1 0 0 1 1 1 1 SET domain dsDNA_bind PF01984.15 KUM66379.1 - 9.7e-36 122.0 10.4 1.1e-35 121.8 7.2 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4615 PF15393.1 KUM66379.1 - 0.11 12.6 0.6 0.16 12.1 0.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4615) Med4 PF10018.4 KUM66379.1 - 3 7.2 8.6 13 5.1 6.0 1.9 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Coq4 PF05019.8 KUM66380.1 - 8.6e-99 328.9 0.0 1e-98 328.6 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Sec2p PF06428.6 KUM66381.1 - 4.2e-29 100.3 12.1 1.2e-28 98.9 8.4 1.7 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p V_ATPase_I PF01496.14 KUM66381.1 - 1.5 6.6 8.4 2 6.1 5.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_M18 PF02127.10 KUM66382.1 - 7.6e-161 535.4 0.0 9.4e-161 535.1 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) DUF1746 PF08508.5 KUM66383.1 - 1.1e-30 105.9 0.4 1.5e-30 105.4 0.3 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) ADH_zinc_N_2 PF13602.1 KUM66384.1 - 2.3e-11 44.7 0.0 5.2e-11 43.5 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM66384.1 - 1.1e-09 37.9 0.0 2.2e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KUM66384.1 - 1.3e-08 34.4 0.0 2.1e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Oxidored_nitro PF00148.14 KUM66384.1 - 0.062 11.9 0.0 0.33 9.5 0.0 1.8 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase NUDIX PF00293.23 KUM66385.1 - 4.1e-12 45.9 0.0 6.6e-12 45.2 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain LETM1 PF07766.8 KUM66386.1 - 5.5e-102 340.3 0.1 8.5e-102 339.7 0.0 1.3 1 0 0 1 1 1 1 LETM1-like protein Fungal_trans PF04082.13 KUM66387.1 - 0.016 14.0 0.0 0.048 12.5 0.0 1.8 2 0 0 2 2 2 0 Fungal specific transcription factor domain Hydrolase_6 PF13344.1 KUM66388.1 - 3.3e-30 103.9 0.0 5.8e-30 103.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KUM66388.1 - 2.7e-12 47.5 0.0 4.4e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KUM66388.1 - 1.2e-11 44.1 0.0 8.6e-11 41.4 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 KUM66388.1 - 1.5e-06 28.5 0.1 2.7e-05 24.4 0.0 2.5 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase PNK3P PF08645.6 KUM66388.1 - 0.05 13.0 0.0 6.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Polynucleotide kinase 3 phosphatase Acid_phosphat_B PF03767.9 KUM66388.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) TauD PF02668.11 KUM66389.1 - 8.9e-40 136.9 0.8 1.1e-39 136.7 0.6 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 KUM66390.1 - 1.3e-59 201.7 60.2 4.3e-50 170.3 32.9 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM66390.1 - 6.2e-14 51.4 32.7 1.1e-12 47.2 7.7 2.9 1 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 KUM66390.1 - 5.3e-11 41.4 13.6 5.3e-11 41.4 9.4 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Methyltransf_11 PF08241.7 KUM66391.1 - 1.5e-13 51.0 0.0 4.4e-13 49.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM66391.1 - 3.7e-10 40.3 0.0 6.6e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KUM66391.1 - 5.8e-09 35.8 0.0 1.4e-08 34.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KUM66391.1 - 7.3e-08 32.7 0.0 4.2e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM66391.1 - 7.3e-08 32.1 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM66391.1 - 1.4e-06 28.7 0.0 2.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 KUM66391.1 - 0.0032 16.3 0.0 0.0078 15.1 0.0 1.5 2 0 0 2 2 2 1 DREV methyltransferase Methyltransf_26 PF13659.1 KUM66391.1 - 0.022 14.7 0.0 0.068 13.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 KUM66391.1 - 0.091 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Mito_carr PF00153.22 KUM66392.1 - 1.2e-58 194.7 1.0 1.6e-20 72.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Redoxin PF08534.5 KUM66393.1 - 1.4e-09 37.6 0.0 1.5e-09 37.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin UBX PF00789.15 KUM66395.1 - 2.3e-09 37.1 0.0 5.6e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 UBX domain ApbA_C PF08546.6 KUM66396.1 - 4.4e-33 113.9 0.0 7e-33 113.2 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KUM66396.1 - 1.3e-24 86.3 0.0 3.3e-24 85.0 0.0 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 KUM66396.1 - 0.15 11.8 0.1 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 ThiF family DUF3176 PF11374.3 KUM66397.1 - 2.5e-38 130.3 0.6 4.8e-38 129.4 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Fungal_trans PF04082.13 KUM66398.1 - 1.8e-12 46.7 0.1 2.7e-12 46.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM66398.1 - 1.8e-10 40.5 10.2 3.6e-10 39.5 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain POT1 PF02765.12 KUM66399.1 - 8.6e-13 48.4 0.0 1.4e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 HDA2-3 PF11496.3 KUM66400.1 - 4.9e-53 179.8 0.0 1.4e-52 178.3 0.0 1.8 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.19 KUM66400.1 - 0.0046 16.5 0.7 0.013 15.1 0.5 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain TMEM192 PF14802.1 KUM66400.1 - 0.095 11.5 1.9 0.19 10.5 1.3 1.5 1 0 0 1 1 1 0 TMEM192 family T2SF PF00482.18 KUM66400.1 - 0.39 10.6 7.8 1 9.2 2.6 3.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Fez1 PF06818.10 KUM66400.1 - 5.4 6.9 36.1 1.8 8.5 7.9 2.8 1 1 1 2 2 2 0 Fez1 FMO-like PF00743.14 KUM66401.1 - 6.8e-39 133.4 0.0 5.3e-22 77.7 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KUM66401.1 - 1.4e-17 64.4 0.0 4.4e-17 62.8 0.0 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KUM66401.1 - 1e-11 44.4 0.0 4.9e-08 32.2 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KUM66401.1 - 1.1e-11 44.7 0.0 6.1e-11 42.3 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KUM66401.1 - 1.2e-09 38.4 0.0 4e-08 33.3 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM66401.1 - 2.4e-06 27.4 0.0 6.6e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KUM66401.1 - 5.8e-05 22.2 0.1 0.00034 19.7 0.0 2.0 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 KUM66401.1 - 0.005 15.7 0.0 2.9 6.6 0.0 2.8 2 1 1 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 KUM66401.1 - 0.013 13.9 0.2 0.37 9.1 0.0 2.3 3 0 0 3 3 3 0 HI0933-like protein Semialdhyde_dh PF01118.19 KUM66401.1 - 0.075 13.3 0.0 1.1 9.5 0.0 2.5 2 1 1 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain Trs65 PF12735.2 KUM66402.1 - 2.3e-94 316.1 0.1 2.9e-94 315.8 0.1 1.1 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 Trp_DMAT PF11991.3 KUM66404.1 - 4.6e-72 243.2 0.0 5.8e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase FF PF01846.14 KUM66405.1 - 2e-53 178.1 17.8 1.5e-15 56.8 0.8 6.7 6 0 0 6 6 6 5 FF domain WW PF00397.21 KUM66405.1 - 6.8e-19 67.4 10.0 2.3e-09 36.9 2.0 2.6 2 0 0 2 2 2 2 WW domain PGK PF00162.14 KUM66406.1 - 1.4e-141 471.5 0.5 1.6e-141 471.3 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DSS1_SEM1 PF05160.8 KUM66407.1 - 1.5e-18 66.3 13.3 1.8e-10 40.3 5.8 2.2 2 0 0 2 2 2 2 DSS1/SEM1 family Mpv17_PMP22 PF04117.7 KUM66408.1 - 8.9e-22 76.5 0.1 8.9e-22 76.5 0.1 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family AMP-binding PF00501.23 KUM66410.1 - 1.8e-155 517.4 0.0 3e-78 263.0 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KUM66410.1 - 3.4e-64 216.5 0.0 3.2e-33 114.8 0.0 3.5 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KUM66410.1 - 2.6e-21 75.6 0.2 1.6e-10 41.0 0.0 3.1 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KUM66410.1 - 1.6e-10 41.7 0.0 0.00027 21.7 0.0 3.1 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 KUM66410.1 - 0.016 15.4 0.2 0.056 13.7 0.1 2.1 2 0 0 2 2 2 0 HxxPF-repeated domain Clr5 PF14420.1 KUM66410.1 - 0.19 11.6 0.0 0.48 10.3 0.0 1.6 1 0 0 1 1 1 0 Clr5 domain MFS_1 PF07690.11 KUM66411.1 - 3.9e-39 134.3 39.3 3.9e-39 134.3 27.2 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KUM66411.1 - 1.5e-13 49.8 10.7 2.3e-13 49.2 7.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Hydrophobin PF01185.13 KUM66412.1 - 0.019 15.3 5.0 0.034 14.5 3.5 1.5 1 0 0 1 1 1 0 Fungal hydrophobin Macoilin PF09726.4 KUM66414.1 - 0.68 8.1 3.4 0.69 8.1 2.3 1.0 1 0 0 1 1 1 0 Transmembrane protein Helicase_C_3 PF13625.1 KUM66415.1 - 2.5e-28 98.3 0.0 9.8e-28 96.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KUM66415.1 - 5.2e-15 55.7 0.0 1.1e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KUM66415.1 - 2.2e-12 46.6 0.0 4.9e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KUM66415.1 - 4.5e-12 45.3 0.0 7.4e-12 44.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 KUM66415.1 - 3e-06 26.8 0.1 6.9e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_34 PF13872.1 KUM66415.1 - 0.0032 16.2 0.1 0.005 15.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 CTD_bind PF04818.8 KUM66417.1 - 0.00014 22.0 0.0 0.00025 21.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II-binding domain. MIP-T3 PF10243.4 KUM66417.1 - 0.11 11.0 6.9 0.14 10.5 4.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 AA_permease PF00324.16 KUM66418.1 - 4.4e-54 183.6 28.6 5.2e-54 183.3 19.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KUM66418.1 - 3.4e-19 68.7 31.8 4.2e-19 68.4 22.1 1.0 1 0 0 1 1 1 1 Amino acid permease Amino_oxidase PF01593.19 KUM66419.1 - 6.8e-41 140.7 0.2 2.9e-26 92.5 0.0 2.1 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KUM66419.1 - 8.5e-13 48.1 0.5 1.6e-12 47.2 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KUM66419.1 - 1.2e-08 35.2 0.1 3.7e-05 23.8 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KUM66419.1 - 1e-07 31.1 1.1 1.6e-07 30.5 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KUM66419.1 - 2.5e-07 29.9 0.1 7.9e-07 28.2 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KUM66419.1 - 3.6e-06 25.7 0.3 7e-06 24.7 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 KUM66419.1 - 6.2e-05 22.2 0.2 7.7e-05 21.9 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KUM66419.1 - 0.00015 22.0 0.7 0.00061 20.1 0.1 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KUM66419.1 - 0.00021 20.2 1.4 0.00029 19.8 0.9 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KUM66419.1 - 0.00048 20.0 0.1 0.0012 18.8 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KUM66419.1 - 0.00051 19.2 0.2 0.0015 17.6 0.1 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 KUM66419.1 - 0.0024 17.0 0.2 0.0039 16.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 KUM66419.1 - 0.025 13.5 0.7 0.044 12.7 0.2 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein PALP PF00291.20 KUM66420.1 - 1e-11 44.6 0.0 1.2e-11 44.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DHHA2 PF02833.9 KUM66421.1 - 5.4e-13 49.2 0.0 8.6e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 KUM66421.1 - 4.9e-06 26.2 0.0 0.0007 19.2 0.0 2.2 2 0 0 2 2 2 2 DHH family Sugar_tr PF00083.19 KUM66422.1 - 6.8e-75 252.3 16.1 8.4e-75 252.0 11.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM66422.1 - 3.2e-21 75.4 19.8 3.2e-21 75.4 13.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Transglut_core PF01841.14 KUM66423.1 - 1.9e-08 34.4 0.0 4e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.12 KUM66423.1 - 3e-08 33.0 0.1 8.4e-08 31.5 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KUM66423.1 - 2.3e-06 26.8 0.0 6.6e-06 25.4 0.0 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KUM66423.1 - 1.8e-05 24.2 0.2 5.5e-05 22.6 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain ketoacyl-synt PF00109.21 KUM66424.1 - 5e-77 258.8 0.0 8.9e-77 257.9 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KUM66424.1 - 1.7e-49 168.8 0.0 6e-49 167.0 0.0 1.9 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KUM66424.1 - 3.9e-32 110.5 0.0 1.1e-31 109.1 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 KUM66424.1 - 1.2e-26 94.3 0.0 4.1e-26 92.6 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 KUM66424.1 - 5.8e-23 80.9 6.2 2.9e-12 46.6 1.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 KUM66424.1 - 8.4e-11 41.5 0.0 1.5e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.18 KUM66424.1 - 8.5e-05 21.6 0.0 0.00018 20.5 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.2 KUM66424.1 - 0.00011 22.2 0.2 0.0043 16.9 0.0 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family UME PF08064.8 KUM66424.1 - 0.087 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 UME (NUC010) domain MFS_1 PF07690.11 KUM66425.1 - 1.4e-40 139.1 60.0 1e-39 136.2 24.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2583 PF10762.4 KUM66425.1 - 0.31 11.2 8.4 0.45 10.6 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) DUF3808 PF10300.4 KUM66426.1 - 8.7e-158 525.7 0.6 1e-157 525.4 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) GXWXG PF14231.1 KUM66426.1 - 0.098 12.3 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 GXWXG protein AMP-binding PF00501.23 KUM66427.1 - 0 1020.9 0.1 9.8e-85 284.4 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 KUM66427.1 - 4.7e-250 826.8 0.0 9.9e-50 169.0 0.0 8.1 8 0 0 8 8 8 7 Condensation domain PP-binding PF00550.20 KUM66427.1 - 2.8e-46 155.6 9.3 1.5e-09 37.9 0.1 6.4 6 0 0 6 6 6 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KUM66427.1 - 9.5e-13 48.9 2.6 0.013 16.3 0.0 5.7 6 0 0 6 6 6 4 AMP-binding enzyme C-terminal domain Cwf_Cwc_15 PF04889.7 KUM66427.1 - 6.2 6.4 0.4 11 5.6 0.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BCDHK_Adom3 PF10436.4 KUM66428.1 - 2.3e-44 150.8 0.1 6.2e-44 149.3 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KUM66428.1 - 1.3e-10 40.9 0.0 1.6e-09 37.4 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KUM66428.1 - 0.0066 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 KUM66428.1 - 0.013 15.3 0.0 0.95 9.2 0.0 2.4 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain USP7_ICP0_bdg PF12436.3 KUM66429.1 - 2.7e-89 298.6 0.6 9.4e-89 296.9 0.3 2.0 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 KUM66429.1 - 8.9e-71 237.7 0.4 7.1e-68 228.2 0.0 2.8 2 0 0 2 2 2 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 KUM66429.1 - 1.7e-56 191.3 0.8 3.6e-56 190.2 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KUM66429.1 - 2.2e-34 119.2 0.0 3.8e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 KUM66429.1 - 6.9e-07 29.5 0.0 2.7e-06 27.6 0.0 2.1 1 0 0 1 1 1 1 MATH domain Rad60-SLD PF11976.3 KUM66429.1 - 0.0065 16.1 0.3 0.61 9.8 0.0 4.0 4 1 0 4 4 4 1 Ubiquitin-2 like Rad60 SUMO-like ABC_tran PF00005.22 KUM66430.1 - 8.4e-45 152.4 0.0 2.1e-24 86.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KUM66430.1 - 3.8e-33 115.0 28.9 3.6e-26 92.1 8.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KUM66430.1 - 1.9e-11 43.6 0.0 0.0048 16.1 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KUM66430.1 - 3.1e-10 40.2 0.0 9.8e-06 25.7 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.1 KUM66430.1 - 7.8e-10 39.1 0.0 0.027 14.4 0.0 4.3 2 2 1 4 4 4 2 AAA domain DUF258 PF03193.11 KUM66430.1 - 2.1e-06 26.9 0.0 0.039 13.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KUM66430.1 - 2.3e-06 27.7 0.1 0.062 13.2 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain Zeta_toxin PF06414.7 KUM66430.1 - 5.4e-06 25.6 0.1 0.011 14.8 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin Miro PF08477.8 KUM66430.1 - 1e-05 26.0 0.0 0.19 12.2 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_10 PF12846.2 KUM66430.1 - 1.3e-05 24.7 0.2 0.013 14.9 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain SbcCD_C PF13558.1 KUM66430.1 - 1.7e-05 24.6 0.2 0.092 12.6 0.1 3.1 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit MobB PF03205.9 KUM66430.1 - 3.9e-05 23.3 0.9 0.024 14.3 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 KUM66430.1 - 7.5e-05 22.5 0.0 0.27 10.9 0.0 2.5 2 0 0 2 2 2 2 Archaeal ATPase AAA_29 PF13555.1 KUM66430.1 - 0.00018 20.9 0.2 0.14 11.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 KUM66430.1 - 0.00022 21.1 0.0 0.15 11.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain cobW PF02492.14 KUM66430.1 - 0.00025 20.5 2.2 1.3 8.4 0.0 3.4 3 0 0 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 KUM66430.1 - 0.0006 19.6 0.1 0.078 12.7 0.0 2.5 2 0 0 2 2 2 1 Dynamin family NACHT PF05729.7 KUM66430.1 - 0.00073 19.2 0.1 1.6 8.3 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_25 PF13481.1 KUM66430.1 - 0.00073 18.9 0.0 0.76 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KUM66430.1 - 0.00089 18.7 0.0 0.15 11.5 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family ATP-synt_ab PF00006.20 KUM66430.1 - 0.0014 18.1 0.2 0.59 9.5 0.1 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.18 KUM66430.1 - 0.0016 18.4 0.0 1 9.3 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Septin PF00735.13 KUM66430.1 - 0.0029 16.6 0.1 2 7.3 0.0 2.2 2 0 0 2 2 2 2 Septin T2SE PF00437.15 KUM66430.1 - 0.0048 15.8 0.3 0.052 12.4 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.17 KUM66430.1 - 0.0048 17.0 0.0 2.2 8.5 0.0 2.9 3 0 0 3 3 2 1 RNA helicase IstB_IS21 PF01695.12 KUM66430.1 - 0.0054 16.1 0.3 0.26 10.6 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA PF00004.24 KUM66430.1 - 0.0059 16.8 0.3 2.3 8.4 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KUM66430.1 - 0.0071 16.0 0.1 1.4 8.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) UPF0079 PF02367.12 KUM66430.1 - 0.0085 15.7 0.1 2.6 7.6 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_14 PF13173.1 KUM66430.1 - 0.0095 15.8 0.7 6.4 6.6 0.1 3.1 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 KUM66430.1 - 0.012 15.1 1.6 0.48 9.8 0.1 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PRK PF00485.13 KUM66430.1 - 0.018 14.6 1.0 0.42 10.1 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 KUM66430.1 - 0.021 15.6 1.3 0.36 11.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KUM66430.1 - 0.034 13.7 0.2 0.4 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KUM66430.1 - 0.055 12.3 0.4 3.3 6.4 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Mg_chelatase PF01078.16 KUM66430.1 - 0.069 12.2 0.2 1 8.5 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.13 KUM66430.1 - 0.091 12.2 0.2 11 5.4 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.1 KUM66430.1 - 0.12 12.6 0.2 2.6 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.10 KUM66430.1 - 0.15 10.6 0.4 1.4 7.4 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_18 PF13238.1 KUM66430.1 - 0.24 11.6 1.4 1 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain IF4E PF01652.13 KUM66431.1 - 2.2e-52 176.9 0.0 3.2e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E AAA_16 PF13191.1 KUM66433.1 - 1.7e-10 41.2 1.1 5.3e-09 36.3 0.0 3.9 4 0 0 4 4 4 1 AAA ATPase domain NACHT PF05729.7 KUM66433.1 - 1.2e-06 28.3 0.2 9.5e-06 25.3 0.1 2.6 1 1 0 1 1 1 1 NACHT domain TPR_12 PF13424.1 KUM66433.1 - 8.3e-06 25.6 8.0 1.1 9.2 0.0 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat AAA_22 PF13401.1 KUM66433.1 - 1.2e-05 25.4 0.1 9.9e-05 22.4 0.1 2.7 1 0 0 1 1 1 1 AAA domain TPR_10 PF13374.1 KUM66433.1 - 0.02 14.8 2.8 9.7 6.2 0.0 4.9 7 0 0 7 7 7 0 Tetratricopeptide repeat AAA_19 PF13245.1 KUM66433.1 - 0.037 13.7 0.0 0.16 11.7 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 KUM66433.1 - 0.073 13.3 0.5 0.57 10.4 0.2 2.7 2 1 0 2 2 2 0 AAA domain SPC22 PF04573.7 KUM66434.1 - 5.9e-36 123.3 0.0 3.2e-25 88.3 0.0 2.1 2 0 0 2 2 2 2 Signal peptidase subunit Pmp3 PF01679.12 KUM66435.1 - 4.8e-23 80.5 8.9 6e-23 80.2 6.2 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF3165 PF11364.3 KUM66435.1 - 0.11 12.6 0.5 0.16 12.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3165) Peptidase_C48 PF02902.14 KUM66436.1 - 5.2e-32 111.2 0.0 1.6e-31 109.5 0.0 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain AIG2 PF06094.7 KUM66437.1 - 2.7e-14 53.4 0.1 8.7e-14 51.8 0.1 1.7 1 1 0 1 1 1 1 AIG2-like family Aldolase_II PF00596.16 KUM66438.1 - 1.9e-45 154.7 0.1 2.3e-45 154.4 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain ApbA_C PF08546.6 KUM66439.1 - 4.5e-26 91.2 0.0 8.9e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KUM66439.1 - 6.2e-25 87.3 0.0 8.8e-25 86.9 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 KUM66439.1 - 0.07 12.9 1.2 0.15 11.8 0.8 1.5 1 0 0 1 1 1 0 ThiF family DUF4243 PF14027.1 KUM66440.1 - 5.5e-104 348.1 0.0 6.5e-104 347.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Fungal_trans_2 PF11951.3 KUM66441.1 - 5.5e-56 189.8 4.6 8.8e-56 189.1 3.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM66441.1 - 5.2e-07 29.4 12.1 8.8e-07 28.7 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhyH PF05721.8 KUM66442.1 - 1.5e-16 61.0 0.0 2.9e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 KUM66442.1 - 0.011 14.3 0.0 0.018 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Glyoxalase_3 PF13468.1 KUM66443.1 - 2.4e-25 89.4 0.0 2.8e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain CN_hydrolase PF00795.17 KUM66445.1 - 1.9e-29 102.3 0.0 3e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 KUM66445.1 - 6.6e-14 51.3 0.0 4.9e-13 48.5 0.0 2.3 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 KUM66445.1 - 0.13 11.6 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Asparagine synthase NUDIX-like PF09296.6 KUM66446.1 - 1.9e-21 76.2 0.0 5.2e-21 74.8 0.0 1.8 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain NUDIX PF00293.23 KUM66446.1 - 1.3e-15 57.2 0.1 2.6e-15 56.2 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.6 KUM66446.1 - 2.2e-06 27.0 1.7 4.3e-06 26.1 1.2 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain MFS_1 PF07690.11 KUM66447.1 - 1.3e-30 106.2 52.4 1.3e-30 106.2 36.3 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM66447.1 - 3e-05 22.7 14.4 3e-05 22.7 10.0 4.1 4 1 0 4 4 4 1 Sugar (and other) transporter DUF3335 PF11814.3 KUM66447.1 - 0.066 12.3 0.2 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Peptidase_C39 like family EMP24_GP25L PF01105.19 KUM66448.1 - 2.3e-46 157.8 4.3 2.6e-46 157.6 3.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2012 PF09430.5 KUM66448.1 - 0.043 13.6 0.4 0.087 12.6 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2012) SRP-alpha_N PF04086.8 KUM66449.1 - 0.29 10.4 5.1 0.34 10.2 3.5 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal APC_CDC26 PF10471.4 KUM66449.1 - 1 10.1 7.0 2.9 8.7 4.8 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Ribosomal_L24e PF01246.15 KUM66450.1 - 5.7e-30 102.9 0.4 5.7e-30 102.9 0.3 2.2 2 1 0 2 2 2 1 Ribosomal protein L24e Acetyltransf_1 PF00583.19 KUM66451.1 - 2.6e-09 36.9 0.0 4.6e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KUM66451.1 - 1.3e-08 34.8 0.3 2.3e-08 34.0 0.2 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain eIF-1a PF01176.14 KUM66452.1 - 1.2e-28 98.3 0.1 1.6e-28 97.8 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DUF3124 PF11322.3 KUM66452.1 - 0.067 13.1 0.0 0.096 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3124) Peptidase_S41 PF03572.13 KUM66453.1 - 7.9e-09 35.1 0.0 2e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Peptidase family S41 ERCC4 PF02732.10 KUM66454.1 - 8.5e-25 87.1 0.0 4.8e-24 84.7 0.0 2.3 2 0 0 2 2 2 1 ERCC4 domain HHH_5 PF14520.1 KUM66454.1 - 7.2e-05 22.8 0.0 0.00019 21.5 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain YtzH PF14165.1 KUM66454.1 - 0.05 13.8 0.1 0.16 12.1 0.1 1.9 1 0 0 1 1 1 0 YtzH-like protein Lyase_1 PF00206.15 KUM66456.1 - 2.3e-110 368.6 0.0 3.6e-110 368.0 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 KUM66456.1 - 1.5e-21 76.2 0.0 4.4e-21 74.6 0.0 1.9 1 0 0 1 1 1 1 Fumarase C C-terminus Abhydrolase_3 PF07859.8 KUM66457.1 - 3.8e-56 190.0 0.1 5.2e-56 189.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KUM66457.1 - 8.3e-06 25.1 0.0 0.00042 19.6 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KUM66457.1 - 0.00033 20.6 1.9 0.00067 19.5 0.6 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Aminotran_1_2 PF00155.16 KUM66458.1 - 7.7e-75 252.1 0.0 8.7e-75 251.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II PTCB-BRCT PF12738.2 KUM66459.1 - 2.8e-12 46.2 0.0 5e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KUM66459.1 - 3.1e-07 30.4 0.0 5.5e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.16 KUM66459.1 - 0.00025 21.0 0.0 0.00075 19.5 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.3 KUM66459.1 - 0.0013 18.4 0.0 0.0032 17.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) DUF2461 PF09365.5 KUM66460.1 - 1.6e-54 184.5 0.0 1.5e-35 122.5 0.0 2.5 2 1 0 2 2 2 2 Conserved hypothetical protein (DUF2461) SURF2 PF05477.6 KUM66460.1 - 0.64 9.1 4.6 1.3 8.0 3.2 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Zn_clus PF00172.13 KUM66461.1 - 9e-09 35.1 6.9 1.3e-08 34.6 4.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ARPC4 PF05856.7 KUM66462.1 - 5.8e-73 243.8 3.9 6.4e-73 243.7 2.7 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) RRM_6 PF14259.1 KUM66463.1 - 0.019 14.9 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) 4HBT PF03061.17 KUM66464.1 - 1.1e-06 28.6 0.2 1.9e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily UCH PF00443.24 KUM66465.1 - 1.3e-56 191.7 0.3 1.6e-56 191.4 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KUM66465.1 - 6.7e-18 65.1 6.8 1.7e-16 60.5 4.7 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 KUM66465.1 - 1e-10 40.8 0.2 3.8e-10 39.0 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family POP1 PF06978.6 KUM66466.1 - 3.7e-65 219.1 19.4 7.9e-65 218.0 13.5 1.6 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 KUM66466.1 - 2.5e-29 100.9 0.5 7.7e-29 99.3 0.4 1.9 1 0 0 1 1 1 1 POPLD (NUC188) domain TRI12 PF06609.8 KUM66467.1 - 1.4e-41 142.3 29.1 1.7e-41 142.1 20.1 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KUM66467.1 - 1.7e-20 73.0 58.3 1.1e-19 70.3 36.9 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM66467.1 - 9.7e-14 50.7 5.8 9.7e-14 50.7 4.0 4.2 3 1 1 4 4 4 2 Sugar (and other) transporter DUF1690 PF07956.6 KUM66469.1 - 5.5e-28 97.7 6.2 5.8e-15 55.5 0.1 2.1 2 0 0 2 2 2 2 Protein of Unknown function (DUF1690) Rootletin PF15035.1 KUM66469.1 - 0.0042 17.0 2.8 0.26 11.2 0.1 2.2 2 0 0 2 2 2 2 Ciliary rootlet component, centrosome cohesion Apolipoprotein PF01442.13 KUM66469.1 - 0.012 15.1 4.6 0.33 10.4 1.2 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Atg14 PF10186.4 KUM66469.1 - 0.032 13.1 0.8 0.063 12.2 0.2 1.6 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 zf-C4H2 PF10146.4 KUM66469.1 - 0.15 12.1 1.0 0.26 11.2 0.5 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein Matrilin_ccoil PF10393.4 KUM66469.1 - 0.35 10.2 2.9 16 4.9 0.0 2.5 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Phasin PF05597.6 KUM66469.1 - 0.47 10.2 4.7 0.28 10.9 0.8 2.1 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF883 PF05957.8 KUM66469.1 - 1.5 9.2 5.9 2 8.8 1.5 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) MFS_1 PF07690.11 KUM66470.1 - 4.9e-35 120.8 29.2 7.8e-35 120.2 20.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 KUM66470.1 - 0.029 14.3 2.9 0.037 14.0 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) ESSS PF10183.4 KUM66470.1 - 0.034 14.5 0.2 0.14 12.5 0.1 2.0 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3976 PF13121.1 KUM66470.1 - 0.059 13.2 0.3 0.18 11.6 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3976) DAO PF01266.19 KUM66471.1 - 5e-56 190.1 0.0 5.9e-56 189.9 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KUM66471.1 - 3.7e-05 23.8 0.0 0.041 13.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KUM66471.1 - 5e-05 23.2 0.0 0.071 12.9 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KUM66471.1 - 7.9e-05 22.4 0.0 0.093 12.4 0.0 2.7 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KUM66471.1 - 0.00016 21.6 0.0 0.00044 20.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 KUM66471.1 - 0.00037 20.5 0.0 0.024 14.7 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 KUM66471.1 - 0.00043 19.2 0.1 0.01 14.7 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 KUM66471.1 - 0.0046 15.6 0.1 0.1 11.1 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.19 KUM66471.1 - 0.026 13.3 0.0 1.3 7.7 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain ThiF PF00899.16 KUM66471.1 - 0.027 14.2 0.0 0.061 13.1 0.0 1.6 1 0 0 1 1 1 0 ThiF family GMC_oxred_N PF00732.14 KUM66471.1 - 0.055 12.6 0.0 4.4 6.3 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase FAD_binding_3 PF01494.14 KUM66471.1 - 0.06 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Fungal_trans_2 PF11951.3 KUM66472.1 - 7.7e-67 225.5 2.9 8.6e-67 225.3 2.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldedh PF00171.17 KUM66473.1 - 3.9e-77 259.5 0.0 4.8e-77 259.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1469 PF07332.6 KUM66475.1 - 6.5 6.4 11.9 12 5.6 8.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) GDI PF00996.13 KUM66476.1 - 2e-39 135.1 0.0 2.8e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 GDP dissociation inhibitor MFS_1 PF07690.11 KUM66477.1 - 1.8e-14 53.2 41.9 1.4e-12 47.0 30.2 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3522 PF12036.3 KUM66477.1 - 0.8 9.4 9.7 0.18 11.6 0.1 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF3522) Pro_isomerase PF00160.16 KUM66478.1 - 1.2e-51 175.0 0.0 1.4e-51 174.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_A22B PF04258.8 KUM66479.1 - 3.2e-57 194.2 0.0 1.7e-56 191.9 0.0 1.9 1 1 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 KUM66479.1 - 7.3e-05 22.0 3.1 7.3e-05 22.0 2.1 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1119) DUF3216 PF11505.3 KUM66479.1 - 0.078 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) Synaptobrevin PF00957.16 KUM66480.1 - 2.5e-33 113.5 0.9 2.9e-33 113.3 0.6 1.0 1 0 0 1 1 1 1 Synaptobrevin RNA_polI_A14 PF08203.6 KUM66482.1 - 0.091 13.0 0.1 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 FSH1 PF03959.8 KUM66483.1 - 2.8e-25 89.0 0.0 3.2e-25 88.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KUM66483.1 - 3.3e-05 23.8 0.1 0.0021 17.9 0.1 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM66483.1 - 0.0024 17.6 0.0 0.0031 17.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KUM66483.1 - 0.0072 15.7 0.0 0.0092 15.4 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase adh_short PF00106.20 KUM66484.1 - 4.3e-20 72.3 0.5 4.2e-18 65.8 0.3 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM66484.1 - 1.5e-08 34.4 0.0 2.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM66484.1 - 0.00081 18.8 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KUM66484.1 - 0.0024 17.9 0.1 0.0054 16.8 0.0 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 KUM66484.1 - 0.0034 16.3 0.0 0.0048 15.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein L27 PF02828.11 KUM66484.1 - 0.056 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 L27 domain Epimerase PF01370.16 KUM66485.1 - 5.9e-26 91.3 0.0 8e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KUM66485.1 - 2.2e-14 53.9 0.0 5.4e-13 49.3 0.0 2.4 2 1 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 KUM66485.1 - 1.3e-09 37.1 0.0 3.1e-09 35.9 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KUM66485.1 - 4.8e-09 35.4 0.0 1.6e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 KUM66485.1 - 4.6e-07 29.0 0.0 6.7e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KUM66485.1 - 0.00025 20.0 0.0 0.0028 16.6 0.0 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KUM66485.1 - 0.082 12.8 0.0 0.3 10.9 0.0 1.9 1 1 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.8 KUM66485.1 - 0.1 11.8 0.0 0.85 8.8 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family NAC PF01849.13 KUM66486.1 - 1.4e-22 78.9 0.1 2.4e-22 78.1 0.1 1.4 1 0 0 1 1 1 1 NAC domain Nup35_RRM PF05172.8 KUM66487.1 - 0.0026 17.4 0.0 0.0096 15.6 0.0 1.9 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif His_Phos_2 PF00328.17 KUM66488.1 - 6.6e-30 104.6 0.0 8.3e-30 104.2 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Hydantoinase_B PF02538.9 KUM66489.1 - 4.8e-175 582.7 0.0 6.9e-175 582.2 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KUM66489.1 - 1.7e-98 329.3 1.3 2.6e-98 328.6 0.0 1.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KUM66489.1 - 1.5e-57 193.9 2.4 4.2e-56 189.2 0.1 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.4 KUM66489.1 - 0.011 15.0 0.0 0.025 13.8 0.0 1.6 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature WH1 PF00568.18 KUM66490.1 - 2.7e-29 101.1 0.0 4.2e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 WH1 domain DUF1348 PF07080.6 KUM66491.1 - 1.6e-46 157.6 2.4 1.9e-46 157.4 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) DUF4440 PF14534.1 KUM66491.1 - 1.6e-05 25.0 0.4 2.5e-05 24.4 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 KUM66491.1 - 6.5e-05 23.2 2.4 0.0001 22.6 1.6 1.5 1 1 0 1 1 1 1 SnoaL-like domain Pkinase PF00069.20 KUM66492.1 - 1.6e-69 233.9 0.0 2.8e-69 233.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM66492.1 - 2.1e-34 118.8 0.0 1.3e-32 112.8 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KUM66492.1 - 2.6e-05 24.0 0.1 0.0026 17.5 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KUM66492.1 - 0.00021 20.4 0.0 0.00056 19.0 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KUM66492.1 - 0.00069 18.6 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF844 PF05815.6 KUM66492.1 - 0.0053 15.6 0.0 0.014 14.2 0.0 1.6 2 0 0 2 2 2 1 Baculovirus protein of unknown function (DUF844) Choline_kinase PF01633.15 KUM66492.1 - 0.0078 15.8 0.0 0.022 14.3 0.0 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase P5CR_dimer PF14748.1 KUM66493.1 - 2.9e-30 104.4 4.7 3.7e-30 104.0 1.6 2.2 2 1 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KUM66493.1 - 3e-13 49.9 0.3 8.4e-13 48.5 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent BacteriocIIc_cy PF12173.3 KUM66493.1 - 0.34 10.9 3.8 1.3 9.0 0.4 2.3 2 0 0 2 2 2 0 Bacteriocin class IIc cyclic gassericin A-like DAO PF01266.19 KUM66494.1 - 1.7e-08 33.7 0.1 8.3e-06 24.9 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KUM66494.1 - 0.00017 21.5 0.1 0.0003 20.7 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KUM66494.1 - 0.0043 15.9 0.1 0.0052 15.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KUM66494.1 - 0.0079 16.0 0.2 0.013 15.3 0.2 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KUM66494.1 - 0.011 15.8 0.3 0.02 14.9 0.1 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KUM66494.1 - 0.013 15.8 0.0 0.026 14.9 0.0 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KUM66494.1 - 0.028 13.3 0.0 0.37 9.6 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein ThiF PF00899.16 KUM66494.1 - 0.03 14.1 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 ThiF family NAD_Gly3P_dh_N PF01210.18 KUM66494.1 - 0.037 13.7 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.12 KUM66494.1 - 0.15 11.1 0.1 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Redoxin PF08534.5 KUM66495.1 - 6.4e-34 116.6 0.0 7.1e-34 116.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KUM66495.1 - 1.4e-15 57.0 0.0 1.8e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family MFS_1 PF07690.11 KUM66496.1 - 5.6e-45 153.5 56.8 3.8e-44 150.8 36.9 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM66496.1 - 1.1e-16 60.5 15.3 1.1e-16 60.5 10.6 2.5 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KUM66496.1 - 2.8e-15 55.5 22.7 2.8e-15 55.5 15.8 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) UQ_con PF00179.21 KUM66497.1 - 1.5e-46 157.3 0.0 1.7e-46 157.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KUM66497.1 - 4.6e-05 23.1 0.0 5.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KUM66497.1 - 0.012 15.3 0.1 0.022 14.4 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 KUM66497.1 - 0.06 13.2 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 RWD domain WD40 PF00400.27 KUM66498.1 - 1.2e-14 53.4 13.4 0.00022 20.9 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat zf-C3HC4_2 PF13923.1 KUM66498.1 - 0.00097 19.1 7.7 0.00097 19.1 5.3 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KUM66498.1 - 0.0061 16.3 8.2 0.0061 16.3 5.7 2.4 2 0 0 2 2 2 1 Ring finger domain RWD PF05773.17 KUM66498.1 - 0.053 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 RWD domain Elf1 PF05129.8 KUM66498.1 - 0.13 12.0 1.3 0.66 9.7 0.3 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like IBR PF01485.16 KUM66498.1 - 0.26 11.2 9.9 3.1 7.7 6.6 2.8 2 1 0 2 2 2 0 IBR domain SH3_1 PF00018.23 KUM66500.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 0 SH3 domain SH3_9 PF14604.1 KUM66500.1 - 0.06 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain NAD_binding_6 PF08030.7 KUM66501.1 - 2.4e-22 79.5 0.0 4.3e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KUM66501.1 - 1.6e-17 63.7 9.4 1.6e-17 63.7 6.5 2.9 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KUM66501.1 - 3.2e-15 55.8 0.0 7.6e-15 54.6 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 KUM66501.1 - 0.00018 22.0 0.0 0.25 11.9 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain RNase_PH PF01138.16 KUM66502.1 - 1.5e-13 51.2 0.2 8e-13 48.8 0.1 2.1 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 p450 PF00067.17 KUM66503.1 - 9.1e-64 215.6 0.0 1.2e-63 215.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HAMP PF00672.20 KUM66503.1 - 0.027 14.6 0.3 0.058 13.5 0.2 1.4 1 0 0 1 1 1 0 HAMP domain zf-C2HC5 PF06221.8 KUM66504.1 - 1.8e-22 78.8 3.3 2.8e-22 78.2 2.3 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Sgf11 PF08209.6 KUM66505.1 - 2.1e-06 26.9 0.9 2.1e-06 26.9 0.6 2.1 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 KUM66505.1 - 0.022 14.4 0.9 0.04 13.5 0.6 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 KUM66505.1 - 0.33 11.3 1.8 8.1 6.9 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.21 KUM66505.1 - 1.3 9.5 3.9 6.8 7.2 0.4 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Acetyltransf_1 PF00583.19 KUM66506.1 - 0.00049 20.0 0.0 0.018 15.0 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Hexokinase_2 PF03727.11 KUM66507.1 - 4.6e-71 238.8 0.0 6.1e-71 238.4 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KUM66507.1 - 3.3e-62 209.4 0.0 5.1e-62 208.8 0.0 1.3 1 0 0 1 1 1 1 Hexokinase LacAB_rpiB PF02502.13 KUM66507.1 - 0.057 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Ribose/Galactose Isomerase Aldo_ket_red PF00248.16 KUM66508.1 - 2e-65 220.4 0.0 2.3e-65 220.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 KUM66509.1 - 4.7e-45 153.8 49.1 4.7e-45 153.8 34.0 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Mpv17_PMP22 PF04117.7 KUM66510.1 - 7.3e-10 38.3 0.1 1.5e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Zn_clus PF00172.13 KUM66511.1 - 1.5e-05 24.8 16.2 1.5e-05 24.8 11.3 2.2 2 1 1 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KUM66511.1 - 0.018 13.9 0.2 0.027 13.3 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Chitin_synth_1 PF01644.12 KUM66512.1 - 3.6e-68 228.4 0.0 5.1e-68 227.9 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 KUM66512.1 - 3e-28 98.5 0.0 6.2e-22 77.6 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 KUM66512.1 - 7.9e-26 89.5 0.1 2.3e-25 88.0 0.1 1.7 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 KUM66512.1 - 1.6e-11 44.2 0.0 1.6e-11 44.2 0.0 2.7 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KUM66512.1 - 1.5e-08 34.7 0.0 3.5e-08 33.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 RAP1 PF07218.6 KUM66513.1 - 0.078 11.0 4.1 0.093 10.8 2.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Sporozoite_P67 PF05642.6 KUM66513.1 - 0.3 8.9 6.6 0.28 8.9 4.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Alpha_GJ PF03229.8 KUM66513.1 - 0.42 10.9 9.5 0.07 13.4 2.1 2.1 2 0 0 2 2 2 0 Alphavirus glycoprotein J Meleagrin PF08189.6 KUM66513.1 - 0.43 10.0 0.1 0.43 10.0 0.0 2.3 3 0 0 3 3 3 0 Meleagrin/Cygnin family DUF619 PF04768.8 KUM66514.1 - 1.1e-54 184.3 0.2 2.3e-54 183.3 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 KUM66514.1 - 3.2e-29 101.6 0.0 1.2e-28 99.8 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 KUM66514.1 - 3.7e-24 85.5 0.0 7.3e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 KUM66514.1 - 0.018 14.9 0.0 0.084 12.7 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Rad21_Rec8_N PF04825.8 KUM66515.1 - 2.2e-25 88.7 0.0 4.8e-25 87.6 0.0 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KUM66515.1 - 0.0014 17.7 0.0 0.0045 16.1 0.0 1.8 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DUF3237 PF11578.3 KUM66516.1 - 1.6e-37 128.1 0.0 2.4e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.10 KUM66516.1 - 1.2e-07 31.4 2.3 0.0048 16.6 0.2 2.5 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_2 PF12756.2 KUM66516.1 - 0.024 14.7 4.2 2.4 8.3 0.1 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Herpes_capsid PF06112.6 KUM66516.1 - 0.36 10.8 3.1 16 5.5 2.1 2.8 2 1 0 2 2 2 0 Gammaherpesvirus capsid protein DUF605 PF04652.11 KUM66516.1 - 5.8 6.2 11.3 7.8 5.7 7.8 1.2 1 0 0 1 1 1 0 Vta1 like TPR_11 PF13414.1 KUM66518.1 - 1.4e-46 156.0 22.0 1.7e-11 43.6 0.3 7.8 4 2 3 8 8 8 8 TPR repeat TPR_1 PF00515.23 KUM66518.1 - 3.3e-37 124.5 24.8 0.0012 18.3 0.0 11.2 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 KUM66518.1 - 1.5e-34 115.1 26.0 6.1e-05 22.6 0.0 11.0 10 1 1 11 11 11 8 Tetratricopeptide repeat TPR_16 PF13432.1 KUM66518.1 - 1.5e-24 86.0 12.0 3e-05 24.5 0.0 6.6 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 KUM66518.1 - 4.1e-20 71.5 30.0 1.4e-07 31.3 0.1 7.7 4 1 4 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 KUM66518.1 - 2.4e-17 61.3 17.5 0.081 12.7 0.0 9.2 9 1 1 10 10 9 5 Tetratricopeptide repeat TPR_17 PF13431.1 KUM66518.1 - 2.8e-14 52.0 11.8 0.11 12.7 0.0 8.8 10 0 0 10 10 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 KUM66518.1 - 1.4e-12 47.0 15.8 0.037 14.6 0.0 8.2 7 2 2 9 9 8 4 Tetratricopeptide repeat TPR_9 PF13371.1 KUM66518.1 - 3.6e-12 45.9 11.6 2.5e-05 24.0 0.1 6.1 4 1 3 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 KUM66518.1 - 7.4e-11 40.9 18.7 0.026 14.3 0.1 8.7 7 1 1 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 KUM66518.1 - 2e-09 37.4 15.9 0.0046 17.0 0.2 5.2 3 1 3 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KUM66518.1 - 1e-08 35.4 18.8 2.1e-05 24.7 0.3 6.5 6 1 3 9 9 9 2 Tetratricopeptide repeat MAS20 PF02064.10 KUM66518.1 - 5.9e-05 22.9 0.7 2.4 8.0 0.0 4.2 3 1 1 4 4 4 1 MAS20 protein import receptor SHNi-TPR PF10516.4 KUM66518.1 - 0.00023 20.3 7.6 0.89 8.8 0.0 5.9 5 0 0 5 5 5 1 SHNi-TPR TPR_6 PF13174.1 KUM66518.1 - 0.00029 21.0 22.5 3.3 8.3 0.5 7.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.1 KUM66518.1 - 0.0092 15.8 10.8 2.5 8.1 0.3 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat PPP4R2 PF09184.6 KUM66518.1 - 0.013 15.0 3.6 2.3 7.7 0.0 2.3 2 0 0 2 2 2 0 PPP4R2 SpoIIIAH PF12685.2 KUM66518.1 - 0.04 13.4 4.6 0.032 13.7 1.7 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein Apc5 PF12862.2 KUM66518.1 - 1.9 8.3 12.9 13 5.7 0.0 4.4 4 2 1 5 5 4 0 Anaphase-promoting complex subunit 5 Sel1 PF08238.7 KUM66518.1 - 2.3 8.9 10.3 0.85 10.3 0.1 4.4 4 0 0 4 4 4 0 Sel1 repeat FHA PF00498.21 KUM66519.1 - 1.5e-12 47.3 0.0 3e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain Aldo_ket_red PF00248.16 KUM66520.1 - 5.3e-74 248.5 0.0 5.9e-74 248.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Abhydrolase_3 PF07859.8 KUM66521.1 - 5.8e-18 65.2 0.0 8.1e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KUM66521.1 - 5e-08 32.8 0.0 1e-07 31.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KUM66521.1 - 1.1e-06 27.9 0.0 0.0032 16.7 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.23 KUM66521.1 - 2.6e-06 26.4 0.0 6.4e-06 25.1 0.0 1.5 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.2 KUM66521.1 - 4.5e-06 26.6 0.1 6.3e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KUM66521.1 - 0.001 17.6 0.0 0.29 9.5 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 KUM66521.1 - 0.0015 18.1 0.0 0.043 13.3 0.0 2.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 KUM66521.1 - 0.036 13.5 0.0 0.11 11.8 0.0 1.7 1 1 0 1 1 1 0 Putative esterase Esterase_phd PF10503.4 KUM66521.1 - 0.049 12.8 0.0 0.094 11.9 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase DUF3500 PF12006.3 KUM66523.1 - 1.8e-103 345.8 0.0 2e-103 345.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) DUF2914 PF11141.3 KUM66523.1 - 0.079 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) L_HGMIC_fpl PF10242.4 KUM66524.1 - 1.4e-05 25.1 4.2 2.4e-05 24.4 2.9 1.3 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.1 KUM66524.1 - 0.00026 20.7 5.9 0.00042 20.0 4.1 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF4083 PF13314.1 KUM66524.1 - 0.15 11.9 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) SPC12 PF06645.8 KUM66524.1 - 0.58 9.9 6.8 1 9.1 0.1 3.1 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) RRM_1 PF00076.17 KUM66525.1 - 4e-54 180.1 0.1 1.1e-20 73.0 0.1 4.8 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM66525.1 - 1.9e-46 155.8 0.2 1.8e-16 59.8 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM66525.1 - 2.8e-32 110.3 0.0 6e-13 48.4 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KUM66525.1 - 0.00045 19.9 0.0 2.3 8.0 0.0 4.2 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.6 KUM66525.1 - 0.0053 16.1 0.9 0.017 14.5 0.6 1.9 1 0 0 1 1 1 1 Lsm interaction motif Apt1 PF10351.4 KUM66525.1 - 0.0093 14.8 0.7 1.5 7.5 0.0 2.2 2 0 0 2 2 2 2 Golgi-body localisation protein domain U3_assoc_6 PF08640.6 KUM66525.1 - 0.031 14.0 0.8 0.91 9.3 0.2 2.8 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 tRNA-synt_1b PF00579.20 KUM66526.1 - 9.1e-19 67.6 0.1 3.1e-18 65.9 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Aminotran_4 PF01063.14 KUM66527.1 - 5.5e-39 134.0 0.0 6.8e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class IV Amino_oxidase PF01593.19 KUM66528.1 - 2.8e-50 171.7 0.1 4.1e-50 171.1 0.1 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KUM66528.1 - 5.5e-12 45.5 0.3 1.1e-11 44.5 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KUM66528.1 - 4.2e-10 39.0 0.0 4.3e-08 32.4 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KUM66528.1 - 8.4e-07 28.3 0.2 1.6e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KUM66528.1 - 1.3e-06 27.5 0.5 2e-06 26.9 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KUM66528.1 - 3.4e-06 26.4 0.0 5.4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KUM66528.1 - 0.00014 21.0 0.7 0.00023 20.3 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 KUM66528.1 - 0.00022 20.2 0.0 0.00032 19.6 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KUM66528.1 - 0.00028 20.8 0.0 0.00046 20.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KUM66528.1 - 0.00029 19.4 0.0 0.00066 18.2 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 KUM66528.1 - 0.0003 20.9 2.1 0.042 13.8 0.8 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KUM66528.1 - 0.00037 20.8 0.1 0.0014 18.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KUM66528.1 - 0.0013 17.7 0.2 0.0027 16.6 0.2 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 KUM66528.1 - 0.097 12.4 0.2 4.7 6.9 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding AA_permease_2 PF13520.1 KUM66529.1 - 4.5e-18 65.0 11.0 4.9e-18 64.8 7.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM66529.1 - 7.3e-11 41.0 10.8 7.9e-11 40.9 7.5 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3366 PF11846.3 KUM66529.1 - 2.5 7.9 6.4 0.71 9.7 0.5 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF3366) Metallophos PF00149.23 KUM66531.1 - 4.5e-07 29.4 5.9 3.1e-06 26.7 3.4 2.5 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Fungal_trans_2 PF11951.3 KUM66532.1 - 2.2e-16 59.4 0.4 2.7e-16 59.1 0.3 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Maf1 PF09174.5 KUM66534.1 - 4.2e-62 209.1 0.0 5.8e-62 208.7 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator Filament PF00038.16 KUM66535.1 - 8.1e-07 28.8 20.3 8.1e-07 28.8 14.1 4.2 2 2 1 3 3 3 1 Intermediate filament protein WEMBL PF05701.6 KUM66535.1 - 0.00014 20.4 47.1 0.00014 20.4 32.6 1.7 2 0 0 2 2 2 1 Weak chloroplast movement under blue light DUF4200 PF13863.1 KUM66535.1 - 0.0015 18.4 40.5 0.0026 17.7 10.5 5.7 5 1 1 6 6 6 2 Domain of unknown function (DUF4200) TMF_DNA_bd PF12329.3 KUM66535.1 - 0.0096 15.7 2.9 0.0096 15.7 2.0 6.8 7 0 0 7 7 7 4 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 KUM66535.1 - 1.5 7.9 19.3 2.3 7.3 7.6 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 KUM66535.1 - 1.6 8.4 58.8 0.039 13.7 9.5 4.6 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.6 KUM66535.1 - 6.7 6.4 64.9 1.4 8.7 9.3 5.3 2 1 1 4 4 4 0 Autophagy protein 16 (ATG16) MARVEL PF01284.18 KUM66536.1 - 1.7e-29 102.4 12.6 2.1e-29 102.1 8.8 1.0 1 0 0 1 1 1 1 Membrane-associating domain zf-C2HC5 PF06221.8 KUM66536.1 - 0.059 13.1 0.3 0.088 12.5 0.2 1.2 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type SUR7 PF06687.7 KUM66536.1 - 1.3 8.4 11.0 2.8 7.4 7.6 1.6 1 1 0 1 1 1 0 SUR7/PalI family Clat_adaptor_s PF01217.15 KUM66537.1 - 1.5e-53 180.3 1.4 1.8e-53 180.0 1.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Fungal_trans_2 PF11951.3 KUM66537.1 - 0.042 12.4 0.0 0.055 12.0 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain ABC2_membrane PF01061.19 KUM66539.1 - 3.8e-42 143.8 28.0 3.8e-42 143.8 19.4 1.9 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.7 KUM66539.1 - 3.8e-05 23.2 0.2 3.8e-05 23.2 0.2 2.9 3 0 0 3 3 3 1 CDR ABC transporter ABC2_membrane_3 PF12698.2 KUM66539.1 - 1.3 8.0 28.8 1.9 7.4 19.3 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane PF01061.19 KUM66540.1 - 6.1e-49 166.0 20.4 6.1e-49 166.0 14.1 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 KUM66540.1 - 3e-39 134.4 0.0 3.9e-19 69.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KUM66540.1 - 2e-30 104.4 0.0 2e-30 104.4 0.0 2.0 2 0 0 2 2 1 1 CDR ABC transporter ABC_trans_N PF14510.1 KUM66540.1 - 8.6e-17 61.0 0.1 2.1e-16 59.7 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 KUM66540.1 - 1.2e-09 37.7 15.2 1.2e-09 37.7 10.5 2.2 1 1 0 2 2 2 1 ABC-2 family transporter protein AAA_25 PF13481.1 KUM66540.1 - 1.5e-09 37.5 0.0 1.3e-05 24.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KUM66540.1 - 6.1e-06 25.5 0.0 0.0032 16.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ABC2_membrane_2 PF12679.2 KUM66540.1 - 5.5e-05 22.1 1.9 5.5e-05 22.1 1.3 1.9 1 1 1 2 2 2 1 ABC-2 family transporter protein cobW PF02492.14 KUM66540.1 - 6.8e-05 22.3 1.1 0.00097 18.6 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KUM66540.1 - 0.00018 21.3 0.1 0.0064 16.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KUM66540.1 - 0.00018 21.5 0.1 0.023 14.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KUM66540.1 - 0.00019 20.8 1.5 0.026 14.0 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 KUM66540.1 - 0.0041 17.4 0.0 0.039 14.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KUM66540.1 - 0.0042 17.0 0.0 3.1 7.7 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.1 KUM66540.1 - 0.0064 17.3 0.0 0.11 13.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KUM66540.1 - 0.0068 16.1 0.0 1.4 8.7 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 KUM66540.1 - 0.0088 16.1 0.0 0.55 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KUM66540.1 - 0.019 14.6 0.1 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 KUM66540.1 - 0.027 14.0 1.2 1.9 8.1 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 KUM66540.1 - 0.064 12.8 0.2 4.6 6.7 0.1 2.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KUM66540.1 - 0.084 11.9 0.0 5.2 6.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Miro PF08477.8 KUM66540.1 - 0.13 12.7 0.0 15 6.0 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein PufQ PF05398.6 KUM66540.1 - 0.16 12.0 3.0 12 5.9 0.1 2.7 2 0 0 2 2 2 0 PufQ cytochrome subunit ABC2_membrane_4 PF12730.2 KUM66540.1 - 0.69 9.0 26.9 0.073 12.2 8.3 3.1 3 0 0 3 3 3 0 ABC-2 family transporter protein DUF3043 PF11241.3 KUM66540.1 - 5.4 6.5 6.2 4 6.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) MRC1 PF09444.5 KUM66541.1 - 2.8e-39 134.7 20.7 2.8e-39 134.7 14.4 6.2 5 1 1 6 6 6 1 MRC1-like domain KR PF08659.5 KUM66541.1 - 0.0098 15.5 1.1 0.023 14.3 0.7 1.6 1 0 0 1 1 1 1 KR domain DUF2422 PF10337.4 KUM66541.1 - 3.8 6.1 4.4 7.3 5.2 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Plus-3 PF03126.13 KUM66542.1 - 4.7e-30 103.8 0.0 5.6e-29 100.3 0.0 2.3 2 0 0 2 2 2 1 Plus-3 domain HAD_2 PF13419.1 KUM66543.1 - 1.7e-08 34.9 0.1 0.0045 17.2 0.0 2.7 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KUM66543.1 - 5.3e-05 22.8 0.0 0.00026 20.6 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like PqqD PF05402.7 KUM66543.1 - 0.061 13.3 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) 3HCDH_N PF02737.13 KUM66544.1 - 1.5e-29 102.9 0.0 2.1e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KUM66544.1 - 9.9e-18 64.3 0.0 6.2e-17 61.7 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 KUM66544.1 - 0.00047 19.9 0.0 0.0016 18.1 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.13 KUM66544.1 - 0.0047 16.9 0.0 0.02 14.8 0.0 2.0 1 1 0 1 1 1 1 TrkA-N domain NAD_binding_10 PF13460.1 KUM66544.1 - 0.017 15.1 0.1 0.029 14.3 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding ApbA PF02558.11 KUM66544.1 - 0.04 13.3 0.0 0.22 10.9 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 KUM66544.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain XdhC_C PF13478.1 KUM66544.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.5 1 1 0 1 1 1 0 XdhC Rossmann domain NAD_binding_2 PF03446.10 KUM66544.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Chitin_synth_1 PF01644.12 KUM66545.1 - 1.2e-81 272.2 0.0 1.8e-81 271.7 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KUM66545.1 - 9.4e-30 102.1 0.0 1.8e-29 101.2 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KUM66545.1 - 1.8e-22 79.4 5.5 2e-19 69.3 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KUM66545.1 - 5.7e-09 35.9 2.9 5.7e-09 35.9 2.0 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KUM66545.1 - 9.4e-08 32.1 0.0 2.2e-07 30.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 UPF0546 PF10639.4 KUM66546.1 - 5.2e-37 126.1 0.1 7.5e-30 103.0 0.1 2.2 2 0 0 2 2 2 2 Uncharacterised protein family UPF0546 DUF1211 PF06736.6 KUM66546.1 - 0.24 11.5 0.1 0.24 11.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1211) DUF751 PF05421.6 KUM66546.1 - 1.2 9.5 6.1 0.65 10.3 0.6 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF751) EamA PF00892.15 KUM66546.1 - 2.6 8.1 8.7 0.82 9.7 3.3 2.0 2 0 0 2 2 2 0 EamA-like transporter family COQ7 PF03232.8 KUM66547.1 - 9e-62 207.5 0.5 1e-61 207.3 0.3 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 KUM66547.1 - 1e-06 29.1 2.4 4.7e-06 26.9 1.7 1.9 1 1 0 1 1 1 1 Rubrerythrin UPF0184 PF03670.8 KUM66547.1 - 0.056 13.6 0.5 0.083 13.0 0.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) LMWPc PF01451.16 KUM66548.1 - 2.9e-18 66.5 0.0 3.8e-13 49.9 0.0 2.1 1 1 0 2 2 2 2 Low molecular weight phosphotyrosine protein phosphatase Pkinase PF00069.20 KUM66549.1 - 2.7e-59 200.4 0.0 3.9e-59 199.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM66549.1 - 4.3e-20 71.8 0.1 8.1e-20 70.9 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KUM66549.1 - 0.13 11.9 0.0 0.64 9.7 0.0 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family COPIIcoated_ERV PF07970.7 KUM66550.1 - 3.4e-32 111.8 0.2 2.9e-31 108.8 0.2 2.0 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KUM66550.1 - 4.6e-23 81.0 0.0 1e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) C2 PF00168.25 KUM66551.1 - 1.3e-10 40.9 0.0 2.5e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain SprA-related PF12118.3 KUM66551.1 - 0.026 13.8 33.8 0.054 12.8 23.5 1.5 1 0 0 1 1 1 0 SprA-related family Pkinase PF00069.20 KUM66553.1 - 2.1e-72 243.3 0.0 2.9e-72 242.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM66553.1 - 2.7e-35 121.7 0.0 3.7e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 KUM66553.1 - 8.7e-09 35.4 0.0 2.2e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 KUM66553.1 - 1.5e-05 24.1 0.0 2.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KUM66553.1 - 0.0002 20.8 0.1 0.00049 19.5 0.1 1.6 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KUM66553.1 - 0.024 13.7 0.2 0.068 12.2 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.4 KUM66553.1 - 0.027 13.0 0.1 0.04 12.4 0.1 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC CrtC PF07143.6 KUM66553.1 - 0.11 11.7 0.1 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Hydroxyneurosporene synthase (CrtC) APH PF01636.18 KUM66553.1 - 0.12 12.0 0.1 0.12 12.0 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KUM66553.1 - 0.13 11.0 0.2 0.2 10.4 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PhyH PF05721.8 KUM66557.1 - 8.8e-45 153.3 0.0 1.1e-44 153.0 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1826 PF08856.6 KUM66557.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1826) UTP15_C PF09384.5 KUM66558.1 - 1.2e-52 177.4 2.0 1.2e-52 177.4 1.4 1.7 1 1 1 2 2 2 1 UTP15 C terminal WD40 PF00400.27 KUM66558.1 - 9e-29 98.2 1.0 8.2e-08 31.8 0.1 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat PQQ_2 PF13360.1 KUM66558.1 - 0.00013 21.4 0.3 0.011 15.2 0.0 2.5 2 1 0 3 3 3 1 PQQ-like domain CPSF_A PF03178.10 KUM66558.1 - 0.014 14.5 0.0 0.035 13.1 0.0 1.6 2 0 0 2 2 2 0 CPSF A subunit region His_Phos_1 PF00300.17 KUM66559.1 - 3.2e-22 79.3 0.1 5e-22 78.6 0.1 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribosomal_L22 PF00237.14 KUM66560.1 - 1e-17 63.9 0.3 1.1e-15 57.4 0.2 2.5 1 1 0 1 1 1 1 Ribosomal protein L22p/L17e Mito_carr PF00153.22 KUM66561.1 - 4.2e-58 193.0 0.9 2.5e-19 68.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ASC PF00858.19 KUM66561.1 - 0.086 11.4 0.4 0.13 10.9 0.3 1.2 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel Nop16 PF09420.5 KUM66565.1 - 1.9e-55 187.4 6.0 2.4e-55 187.0 4.2 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Pex24p PF06398.6 KUM66566.1 - 1.2e-89 300.6 0.0 1.5e-89 300.3 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF639 PF04842.7 KUM66566.1 - 0.0025 16.0 0.8 0.0038 15.4 0.5 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF639) Anp1 PF03452.9 KUM66567.1 - 2.5e-107 358.0 0.0 3e-107 357.8 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 KUM66567.1 - 0.0064 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 IncA PF04156.9 KUM66567.1 - 0.54 9.8 1.5 1.6 8.3 0.1 2.0 2 0 0 2 2 2 0 IncA protein Zip PF02535.17 KUM66568.1 - 8.1e-59 199.1 6.5 1.8e-58 198.0 4.5 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter E1-E2_ATPase PF00122.15 KUM66569.1 - 7.1e-61 205.1 5.9 1.5e-60 204.0 4.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KUM66569.1 - 1.7e-31 109.1 2.8 1.7e-31 109.1 1.9 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KUM66569.1 - 3.2e-29 102.8 0.0 4e-28 99.3 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KUM66569.1 - 2e-16 59.1 0.0 5.7e-16 57.7 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KUM66569.1 - 1e-13 51.0 0.0 2e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KUM66569.1 - 3.4e-13 50.2 0.0 1.2e-12 48.3 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KUM66569.1 - 3.3e-06 26.8 2.8 9.2e-06 25.4 0.7 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase 2TM PF13239.1 KUM66569.1 - 0.89 9.6 0.0 0.89 9.6 0.0 3.8 4 0 0 4 4 4 0 2TM domain PRELI PF04707.9 KUM66570.1 - 3.4e-25 88.4 0.0 3.5e-21 75.4 0.0 2.2 2 0 0 2 2 2 2 PRELI-like family zf-MYND PF01753.13 KUM66571.1 - 1.9e-09 37.2 8.6 3.3e-09 36.4 6.0 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KUM66571.1 - 0.032 14.0 4.9 0.075 12.9 3.4 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.11 KUM66571.1 - 0.25 11.0 3.3 0.48 10.1 2.3 1.4 1 0 0 1 1 1 0 HIT zinc finger GFA PF04828.9 KUM66572.1 - 5.6e-14 51.8 2.2 1e-13 51.0 1.5 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.6 KUM66572.1 - 0.077 12.8 2.9 1.8 8.4 0.1 2.3 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like DUF35_N PF12172.3 KUM66572.1 - 0.92 9.4 7.7 5.7 6.9 0.0 3.3 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) adh_short PF00106.20 KUM66573.1 - 3.6e-36 124.6 0.1 4.6e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM66573.1 - 2.8e-22 79.6 0.2 3.3e-22 79.4 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM66573.1 - 1.7e-12 47.4 0.0 2.3e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM66573.1 - 1.6e-05 24.5 0.0 2.7e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KUM66573.1 - 2.5e-05 23.1 0.0 3.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.13 KUM66573.1 - 2.6e-05 23.9 0.0 4.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KUM66573.1 - 0.00013 20.9 0.1 0.00019 20.4 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 KUM66573.1 - 0.00067 20.0 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 KUM66573.1 - 0.0022 17.9 0.0 0.0045 16.9 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_10 PF13460.1 KUM66573.1 - 0.0032 17.4 0.0 0.0076 16.2 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding Methyltransf_25 PF13649.1 KUM66573.1 - 0.0041 17.4 0.0 0.0081 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RmlD_sub_bind PF04321.12 KUM66573.1 - 0.0045 15.9 0.0 0.0063 15.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain AlaDh_PNT_C PF01262.16 KUM66573.1 - 0.012 15.1 0.1 0.036 13.6 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 KUM66573.1 - 0.024 14.8 0.0 0.037 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding AdoHcyase_NAD PF00670.16 KUM66573.1 - 0.026 14.3 0.2 0.089 12.6 0.1 1.8 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain THF_DHG_CYH_C PF02882.14 KUM66573.1 - 0.029 13.4 0.1 0.067 12.2 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Methyltransf_12 PF08242.7 KUM66573.1 - 0.031 14.7 0.0 0.052 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Shikimate_DH PF01488.15 KUM66573.1 - 0.031 14.3 0.1 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 KUM66573.1 - 0.056 13.2 0.4 0.27 11.0 0.1 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DFP PF04127.10 KUM66573.1 - 0.085 12.4 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Methyltransf_31 PF13847.1 KUM66573.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_4 PF07993.7 KUM66573.1 - 0.13 11.1 0.1 0.31 9.9 0.1 1.6 1 1 0 1 1 1 0 Male sterility protein DUF4594 PF15266.1 KUM66574.1 - 0.00059 20.0 1.3 0.00074 19.7 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4594) Erp_C PF06780.6 KUM66574.1 - 0.017 14.9 1.9 0.027 14.3 1.3 1.3 1 0 0 1 1 1 0 Erp protein C-terminus TAP_C PF03943.8 KUM66574.1 - 0.059 12.7 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 TAP C-terminal domain GAS PF13851.1 KUM66574.1 - 0.094 11.9 5.8 0.16 11.1 4.0 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Allexi_40kDa PF05549.6 KUM66574.1 - 1.4 8.1 3.8 0.43 9.8 0.9 1.4 2 0 0 2 2 2 0 Allexivirus 40kDa protein V_ATPase_I PF01496.14 KUM66574.1 - 1.7 6.4 4.6 1.9 6.2 3.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 KUM66574.1 - 8.8 5.8 8.4 11 5.5 5.8 1.1 1 0 0 1 1 1 0 IncA protein GAF_2 PF13185.1 KUM66575.1 - 1e-07 32.5 0.0 2.1e-07 31.5 0.0 1.4 1 1 0 1 1 1 1 GAF domain GAF PF01590.21 KUM66575.1 - 1.5e-05 25.2 0.0 1.7e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 KUM66575.1 - 8.2e-05 22.7 0.0 0.00023 21.2 0.0 1.6 1 1 0 2 2 2 1 GAF domain Protoglobin PF11563.3 KUM66575.1 - 0.039 13.6 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 Protoglobin NAD_kinase PF01513.16 KUM66576.1 - 9.4e-70 234.6 0.0 1.3e-69 234.1 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase phage_tail_N PF08400.5 KUM66577.1 - 0.0059 16.3 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Prophage tail fibre N-terminal RNase_PH PF01138.16 KUM66577.1 - 0.014 15.6 0.1 0.039 14.2 0.1 1.7 1 1 0 1 1 1 0 3' exoribonuclease family, domain 1 ImpE PF07024.8 KUM66578.1 - 0.031 14.2 0.0 0.04 13.8 0.0 1.1 1 0 0 1 1 1 0 ImpE protein DUF3638 PF12340.3 KUM66579.1 - 5.4e-22 77.9 0.0 7.3e-22 77.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) FAD_binding_3 PF01494.14 KUM66583.1 - 4.6e-18 65.3 0.1 2.2e-17 63.1 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KUM66583.1 - 1.8e-07 31.0 0.5 4.3e-07 29.8 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KUM66583.1 - 0.0099 14.8 0.8 0.034 13.0 0.3 2.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KUM66583.1 - 0.01 14.7 1.5 0.022 13.6 0.3 2.0 3 0 0 3 3 3 0 FAD binding domain Pyr_redox_2 PF07992.9 KUM66583.1 - 0.02 14.7 0.1 0.041 13.7 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 KUM66583.1 - 0.022 14.5 0.1 0.12 12.2 0.0 2.2 2 0 0 2 2 2 0 ThiF family UDPG_MGDP_dh_N PF03721.9 KUM66583.1 - 0.028 13.8 0.5 0.48 9.7 0.1 2.5 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.9 KUM66583.1 - 0.076 11.6 0.4 0.12 10.9 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.12 KUM66583.1 - 0.11 11.5 0.2 0.2 10.7 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 KUM66583.1 - 0.16 12.3 0.6 0.43 11.0 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1153 PF06627.6 KUM66585.1 - 0.057 13.2 0.0 0.19 11.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1153) WhiA_N PF10298.4 KUM66585.1 - 0.069 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 WhiA N-terminal LAGLIDADG-like domain GMC_oxred_N PF00732.14 KUM66586.1 - 2.4e-26 92.6 0.0 3.7e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KUM66586.1 - 7.5e-20 71.6 0.7 1.6e-19 70.6 0.5 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KUM66586.1 - 1.4e-08 34.0 3.4 0.00013 21.0 0.0 2.7 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KUM66586.1 - 8.9e-07 28.0 0.5 0.0066 15.3 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.9 KUM66586.1 - 1.3e-06 27.1 0.3 2.3e-05 23.0 0.1 2.3 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 KUM66586.1 - 9.1e-06 25.9 0.6 0.0088 16.4 0.1 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KUM66586.1 - 2e-05 23.8 0.1 0.001 18.2 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KUM66586.1 - 3e-05 24.1 0.1 0.55 10.2 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KUM66586.1 - 9.9e-05 21.5 0.1 0.00022 20.4 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 KUM66586.1 - 0.0001 22.2 0.0 0.00035 20.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KUM66586.1 - 0.00015 21.7 0.1 0.02 14.7 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KUM66586.1 - 0.003 16.6 0.3 0.007 15.4 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 KUM66586.1 - 0.0088 14.9 0.0 0.019 13.8 0.0 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KUM66586.1 - 0.017 14.0 0.2 0.039 12.8 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Glyco_hydro_47 PF01532.15 KUM66588.1 - 4.2e-37 127.8 0.0 5.4e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_47 PF01532.15 KUM66589.1 - 7.8e-75 252.2 0.0 8.7e-75 252.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pyr_redox_3 PF13738.1 KUM66590.1 - 4e-23 82.5 0.0 6e-22 78.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KUM66590.1 - 5.4e-16 57.8 0.1 1.8e-13 49.5 0.1 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KUM66590.1 - 7.1e-12 44.9 0.2 1.9e-09 36.9 0.1 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KUM66590.1 - 8.5e-12 45.3 0.0 1.2e-09 38.3 0.0 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KUM66590.1 - 2e-06 27.7 0.0 1.1e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KUM66590.1 - 7.5e-06 26.2 0.2 0.22 11.9 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KUM66590.1 - 0.00018 20.6 0.0 0.0016 17.6 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.19 KUM66590.1 - 0.00062 18.7 0.1 0.002 17.0 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.14 KUM66590.1 - 0.00078 18.6 0.1 0.0078 15.3 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 KUM66590.1 - 0.00081 19.1 0.7 1 9.1 0.0 3.2 2 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 KUM66590.1 - 0.005 15.7 0.0 0.13 11.1 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KUM66590.1 - 0.014 15.0 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 KUM66590.1 - 0.017 14.2 0.0 0.28 10.2 0.0 2.4 2 0 0 2 2 2 0 Thi4 family SnoaL_2 PF12680.2 KUM66590.1 - 0.02 15.2 0.4 0.11 12.9 0.0 2.4 2 1 1 3 3 3 0 SnoaL-like domain HI0933_like PF03486.9 KUM66590.1 - 0.024 13.1 0.1 0.11 10.8 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Shikimate_DH PF01488.15 KUM66590.1 - 0.028 14.5 0.0 9.8 6.2 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 KUM66590.1 - 0.047 13.9 0.0 14 6.0 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_oxidored PF12831.2 KUM66590.1 - 0.087 11.8 0.0 0.76 8.7 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 KUM66590.1 - 0.15 10.9 0.1 1.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF4229 PF14012.1 KUM66591.1 - 0.029 14.2 0.1 0.038 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Myco_arth_vir_N PF09610.5 KUM66591.1 - 0.8 9.7 3.6 1.4 8.9 2.5 1.4 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) CGI-121 PF08617.5 KUM66595.1 - 5.5e-52 175.6 0.6 6.3e-52 175.4 0.4 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Bax1-I PF01027.15 KUM66596.1 - 1.9e-30 106.0 11.9 3.1e-30 105.3 8.3 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2537 PF10801.3 KUM66596.1 - 0.11 12.6 5.9 3.4 7.8 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2537) DUF4282 PF14110.1 KUM66596.1 - 5.1 7.3 7.5 3.3 7.9 0.4 3.2 2 1 2 4 4 4 0 Domain of unknown function (DUF4282) zf-MIZ PF02891.15 KUM66597.1 - 2.9e-10 39.5 0.4 8.1e-10 38.0 0.3 1.8 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KUM66597.1 - 0.0041 16.6 0.2 0.0096 15.4 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit JAB PF01398.16 KUM66598.1 - 1.6e-35 121.2 0.0 3.5e-35 120.1 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KUM66598.1 - 6.3e-26 90.7 2.0 1.1e-25 89.9 1.4 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 KUM66598.1 - 4.4e-09 35.8 0.0 9.1e-09 34.8 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UCR_14kD PF02271.11 KUM66598.1 - 0.1 12.3 0.8 0.15 11.8 0.1 1.7 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Hist_deacetyl PF00850.14 KUM66599.1 - 2.4e-79 266.8 0.0 4.6e-79 265.9 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Nsp1_C PF05064.8 KUM66600.1 - 5.1e-41 139.0 0.5 1.3e-40 137.6 0.4 1.6 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 KUM66600.1 - 3.4e-11 43.3 182.8 0.00064 19.9 25.0 6.4 1 1 4 5 5 5 4 Nucleoporin FG repeat region ParB PF08775.5 KUM66600.1 - 0.045 14.0 0.6 0.1 12.9 0.4 1.5 1 0 0 1 1 1 0 ParB family Laminin_II PF06009.7 KUM66600.1 - 0.065 12.9 7.7 12 5.6 0.2 3.1 1 1 2 3 3 3 0 Laminin Domain II EzrA PF06160.7 KUM66600.1 - 0.38 8.8 5.9 0.18 9.9 0.6 1.9 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA AAA_13 PF13166.1 KUM66600.1 - 0.49 8.7 3.7 0.31 9.4 0.6 1.6 1 1 1 2 2 2 0 AAA domain Tropomyosin_1 PF12718.2 KUM66600.1 - 0.57 10.0 4.9 0.42 10.4 2.5 1.5 1 1 0 1 1 1 0 Tropomyosin like APG6 PF04111.7 KUM66600.1 - 1.2 8.1 5.2 1.7 7.5 3.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 KUM66600.1 - 1.9 8.0 5.7 5.3 6.5 3.9 1.7 1 1 0 1 1 1 0 IncA protein MscS_porin PF12795.2 KUM66600.1 - 2.2 7.5 9.6 7 5.8 0.4 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Spc7 PF08317.6 KUM66600.1 - 3.3 6.2 7.1 0.81 8.2 0.6 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein IATP PF04568.7 KUM66602.1 - 6.8e-26 90.2 0.4 7.4e-26 90.0 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Atg14 PF10186.4 KUM66602.1 - 0.021 13.7 0.0 0.021 13.7 0.0 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Tmemb_cc2 PF10267.4 KUM66602.1 - 0.038 12.5 0.0 0.042 12.4 0.0 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Phage_GP20 PF06810.6 KUM66602.1 - 0.045 13.2 1.0 0.054 12.9 0.7 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 BLOC1_2 PF10046.4 KUM66602.1 - 0.065 13.3 0.7 0.079 13.1 0.5 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Dad2 PF08654.5 KUM66602.1 - 0.24 11.4 1.7 0.3 11.0 1.2 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad2 RBD-FIP PF09457.5 KUM66602.1 - 0.38 10.6 3.3 0.51 10.1 2.1 1.4 1 1 0 1 1 1 0 FIP domain bZIP_2 PF07716.10 KUM66602.1 - 0.39 10.5 4.2 0.54 10.1 2.9 1.2 1 0 0 1 1 1 0 Basic region leucine zipper Ank_2 PF12796.2 KUM66603.1 - 2.6e-71 235.9 3.7 1.2e-13 51.2 0.0 6.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KUM66603.1 - 3.7e-68 222.1 9.2 1.3e-09 37.4 0.0 12.4 12 2 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.1 KUM66603.1 - 1.8e-50 168.4 2.8 1.5e-10 41.2 0.0 9.0 2 2 7 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM66603.1 - 2.9e-49 160.1 4.7 1.6e-06 27.7 0.0 11.9 12 0 0 12 12 12 9 Ankyrin repeat Ank_5 PF13857.1 KUM66603.1 - 4.5e-49 163.3 12.2 4.4e-11 42.6 0.0 8.6 3 2 6 9 9 9 8 Ankyrin repeats (many copies) F-box PF00646.28 KUM66603.1 - 0.12 12.0 1.2 0.71 9.5 0.8 2.0 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.2 KUM66603.1 - 0.16 11.7 0.2 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 F-box-like DUF498 PF04430.9 KUM66604.1 - 1.7e-26 91.9 0.0 2.5e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) ABC_tran PF00005.22 KUM66605.1 - 1.6e-33 115.9 0.0 7.3e-33 113.7 0.0 2.1 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 KUM66605.1 - 7.2e-26 91.2 7.3 7.2e-26 91.2 5.1 2.7 3 0 0 3 3 3 1 ABC transporter transmembrane region SMC_N PF02463.14 KUM66605.1 - 6e-08 32.1 0.3 2.2e-06 27.0 0.0 2.7 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KUM66605.1 - 6.7e-05 22.9 0.1 0.018 14.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KUM66605.1 - 0.0029 17.5 0.4 0.0078 16.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.1 KUM66605.1 - 0.0053 16.6 0.3 0.059 13.2 0.2 2.6 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KUM66605.1 - 0.0071 15.8 0.2 0.019 14.5 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KUM66605.1 - 0.022 14.9 0.6 0.19 11.8 0.4 2.2 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 KUM66605.1 - 0.04 13.1 0.0 0.078 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 KUM66605.1 - 0.074 12.7 0.1 0.82 9.3 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Alk_phosphatase PF00245.15 KUM66607.1 - 2e-110 369.3 0.0 2.4e-110 369.1 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 KUM66607.1 - 0.0019 17.6 0.0 0.0064 15.9 0.0 1.8 2 0 0 2 2 2 1 Metalloenzyme superfamily Cactin_mid PF10312.4 KUM66608.1 - 2.1e-63 213.0 5.9 3.6e-63 212.3 4.1 1.3 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 KUM66608.1 - 1.8e-55 185.8 3.5 3e-55 185.1 2.4 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein WD40 PF00400.27 KUM66610.1 - 2.7e-30 103.1 13.3 1.4e-09 37.4 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KUM66610.1 - 7e-06 25.8 0.0 0.098 12.3 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A zf-rbx1 PF12678.2 KUM66610.1 - 1.7 8.7 6.2 0.83 9.8 0.2 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger XLF PF09302.6 KUM66611.1 - 1.4e-32 112.7 1.8 2.1e-32 112.2 1.3 1.3 1 0 0 1 1 1 1 XLF (XRCC4-like factor) Fork_head PF00250.13 KUM66612.1 - 2.6e-14 53.0 0.0 4.7e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Fork head domain NRDE-2 PF08424.5 KUM66612.1 - 0.092 11.6 0.4 0.13 11.1 0.3 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Ribosomal_L34e PF01199.13 KUM66613.1 - 8e-38 128.5 3.3 1.1e-37 128.1 2.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Glyco_hydro_76 PF03663.9 KUM66614.1 - 1.9e-20 73.6 0.1 4.3e-12 46.1 0.0 3.6 2 2 0 2 2 2 2 Glycosyl hydrolase family 76 ABC_membrane PF00664.18 KUM66615.1 - 6.4e-48 163.5 37.8 1.2e-26 93.7 15.0 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 KUM66615.1 - 7.5e-46 155.8 0.0 4.9e-25 88.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KUM66615.1 - 4.5e-07 30.1 0.1 0.073 13.0 0.1 4.2 3 1 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 KUM66615.1 - 2.2e-06 27.5 0.1 0.042 13.8 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 KUM66615.1 - 3.3e-06 27.5 0.2 0.096 13.1 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein SMC_N PF02463.14 KUM66615.1 - 4.9e-06 25.9 3.0 0.17 11.1 0.6 3.6 3 1 0 3 3 2 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.7 KUM66615.1 - 1e-05 24.7 0.0 0.013 14.5 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_16 PF13191.1 KUM66615.1 - 3.6e-05 23.8 0.8 0.2 11.6 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain AAA_17 PF13207.1 KUM66615.1 - 4.2e-05 24.3 0.2 0.41 11.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 KUM66615.1 - 0.00019 20.6 0.3 0.18 10.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KUM66615.1 - 0.00032 20.1 4.6 0.081 12.4 0.1 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.18 KUM66615.1 - 0.0016 18.2 1.2 0.19 11.5 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_23 PF13476.1 KUM66615.1 - 0.0032 17.8 0.3 0.37 11.0 0.1 2.7 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 KUM66615.1 - 0.0039 16.0 0.6 1.4 7.6 0.1 2.5 2 0 0 2 2 2 2 ArgK protein AAA_22 PF13401.1 KUM66615.1 - 0.011 15.9 0.1 7.8 6.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 KUM66615.1 - 0.012 14.9 0.0 2 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KUM66615.1 - 0.018 14.5 0.1 4 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain DUF87 PF01935.12 KUM66615.1 - 0.032 14.0 2.1 0.24 11.1 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_18 PF13238.1 KUM66615.1 - 0.036 14.3 0.2 13 6.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.8 KUM66615.1 - 0.085 11.7 0.2 8.7 5.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA PF00004.24 KUM66615.1 - 0.088 13.0 0.0 2.4 8.3 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.1 KUM66615.1 - 0.11 11.5 0.0 14 4.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 KUM66615.1 - 0.12 11.7 1.1 3.7 6.9 0.0 2.7 3 0 0 3 3 2 0 FtsK/SpoIIIE family ATP-synt_ab PF00006.20 KUM66615.1 - 0.14 11.6 0.2 8.3 5.8 0.1 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.1 KUM66615.1 - 0.17 11.8 1.6 0.79 9.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF788 PF05620.6 KUM66615.1 - 0.48 10.2 3.9 1.4 8.7 0.9 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF788) DUF912 PF06024.7 KUM66615.1 - 9.3 6.3 9.4 0.71 9.9 1.6 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TPP_enzyme_M PF00205.17 KUM66616.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain RicinB_lectin_2 PF14200.1 KUM66617.1 - 0.00044 20.5 0.0 0.033 14.5 0.0 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Med26 PF08711.6 KUM66617.1 - 0.17 11.4 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 TFIIS helical bundle-like domain MU117 PF15474.1 KUM66618.1 - 9.6e-23 80.4 5.1 2.7e-22 79.0 3.6 1.8 1 0 0 1 1 1 1 Meiotically up-regulated gene family DUF1835 PF08874.5 KUM66619.1 - 0.097 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) LRR_4 PF12799.2 KUM66620.1 - 0.026 14.1 3.3 1.1 9.0 0.2 3.7 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KUM66620.1 - 0.049 13.3 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 F-box-like LRR_8 PF13855.1 KUM66620.1 - 1.4 8.7 7.3 3.1 7.6 1.3 3.2 2 1 0 2 2 2 0 Leucine rich repeat DUF3328 PF11807.3 KUM66622.1 - 0.0014 18.3 1.0 0.016 14.9 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3328) Virul_fac_BrkB PF03631.10 KUM66622.1 - 0.044 13.1 0.1 0.061 12.6 0.1 1.1 1 0 0 1 1 1 0 Virulence factor BrkB FMN_red PF03358.10 KUM66623.1 - 3.9e-30 104.3 0.0 5.5e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 KUM66623.1 - 8e-08 32.0 0.0 1.1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold Transferase PF02458.10 KUM66624.1 - 2.3e-37 128.4 0.0 4e-21 74.9 0.0 3.0 3 0 0 3 3 3 3 Transferase family Sugar_tr PF00083.19 KUM66625.1 - 2.2e-30 105.6 26.9 2.4e-24 85.7 5.2 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KUM66625.1 - 4.6e-27 94.6 27.7 4.6e-27 94.6 19.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily ATG22 PF11700.3 KUM66625.1 - 4.4e-05 22.1 22.1 0.00062 18.3 4.8 3.0 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like DUF4516 PF14990.1 KUM66625.1 - 0.0079 15.7 0.3 0.021 14.3 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4516) DUF1212 PF06738.7 KUM66625.1 - 3 7.2 9.9 3.8 6.9 3.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1212) DUF4231 PF14015.1 KUM66625.1 - 9.2 6.2 11.5 15 5.5 0.0 4.2 4 1 1 5 5 5 0 Protein of unknown function (DUF4231) DUF2205 PF10224.4 KUM66626.1 - 2.8e-31 106.9 3.9 2.8e-31 106.9 2.7 1.6 2 0 0 2 2 2 1 Predicted coiled-coil protein (DUF2205) Macoilin PF09726.4 KUM66626.1 - 0.0018 16.6 4.8 0.0021 16.4 3.3 1.0 1 0 0 1 1 1 1 Transmembrane protein DUF812 PF05667.6 KUM66626.1 - 0.012 14.1 2.5 0.011 14.2 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4140 PF13600.1 KUM66626.1 - 0.015 15.7 1.2 0.029 14.8 0.8 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF972 PF06156.8 KUM66626.1 - 0.017 15.4 3.5 0.029 14.6 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Spectrin PF00435.16 KUM66626.1 - 0.028 14.7 1.2 0.041 14.1 0.8 1.3 1 0 0 1 1 1 0 Spectrin repeat IncA PF04156.9 KUM66626.1 - 0.037 13.6 1.1 0.036 13.6 0.8 1.2 1 0 0 1 1 1 0 IncA protein HALZ PF02183.13 KUM66626.1 - 0.041 13.5 4.4 0.28 10.9 0.1 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper DASH_Dam1 PF08653.5 KUM66626.1 - 0.047 13.4 0.1 0.078 12.7 0.1 1.3 1 0 0 1 1 1 0 DASH complex subunit Dam1 DivIC PF04977.10 KUM66626.1 - 0.07 12.6 2.4 0.12 11.9 1.7 1.5 1 0 0 1 1 1 0 Septum formation initiator Baculo_PEP_C PF04513.7 KUM66626.1 - 0.076 12.8 0.4 0.11 12.3 0.3 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.4 KUM66626.1 - 0.1 12.4 4.9 0.095 12.5 2.3 1.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Glutaredoxin2_C PF04399.8 KUM66626.1 - 0.11 12.1 0.1 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain ADIP PF11559.3 KUM66626.1 - 0.14 12.0 6.1 0.19 11.6 4.3 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding OmpH PF03938.9 KUM66626.1 - 0.33 10.8 6.0 0.46 10.4 4.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF904 PF06005.7 KUM66626.1 - 0.49 10.7 3.9 1.9 8.8 2.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF904) 14-3-3 PF00244.15 KUM66627.1 - 9.2e-115 381.6 5.5 1.1e-114 381.4 3.8 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF3456 PF11938.3 KUM66627.1 - 0.056 13.4 0.3 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP RRM_1 PF00076.17 KUM66628.1 - 1.7e-15 56.3 0.0 2.5e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM66628.1 - 4.1e-13 49.1 0.0 6.1e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM66628.1 - 2.6e-11 43.2 0.0 3.5e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMA PF00403.21 KUM66628.1 - 0.071 13.2 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Heavy-metal-associated domain RRM_3 PF08777.6 KUM66628.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif ER_lumen_recept PF00810.13 KUM66629.1 - 2.4e-37 128.6 7.7 3.7e-37 128.0 5.3 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KUM66629.1 - 0.018 14.5 0.1 0.018 14.5 0.1 3.9 5 1 0 5 5 5 0 PQ loop repeat Myb_DNA-bind_4 PF13837.1 KUM66630.1 - 0.012 15.7 2.9 0.012 15.7 0.1 2.2 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF2360 PF10152.4 KUM66630.1 - 1.5 9.1 7.0 2.9 8.1 3.2 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) PAT1 PF09770.4 KUM66630.1 - 2.5 6.2 10.8 3.5 5.7 7.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ATP-synt_ab PF00006.20 KUM66631.1 - 1.2e-27 96.7 0.0 1.6e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Myb_DNA-binding PF00249.26 KUM66632.1 - 1e-12 47.8 6.1 4.5e-07 29.8 2.0 3.1 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KUM66632.1 - 1.7e-11 43.9 3.3 1.8e-06 27.9 0.4 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Transp_cyt_pur PF02133.10 KUM66633.1 - 1.2e-16 60.3 41.7 2.4e-16 59.3 28.9 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin COX5B PF01215.14 KUM66634.1 - 9.6e-37 125.6 0.0 4.1e-36 123.6 0.0 1.8 1 1 1 2 2 2 1 Cytochrome c oxidase subunit Vb zf-UBP PF02148.14 KUM66634.1 - 0.041 14.0 0.3 0.059 13.4 0.2 1.2 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Myb_DNA-bind_6 PF13921.1 KUM66635.1 - 1e-07 31.9 3.6 0.005 16.9 0.2 2.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KUM66635.1 - 2.7e-06 27.3 0.9 8.1e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain PROCN PF08083.6 KUM66636.1 - 4.2e-222 736.8 7.4 7e-222 736.1 5.1 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 KUM66636.1 - 1.7e-125 416.9 1.6 3.1e-125 416.0 1.1 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 KUM66636.1 - 5.2e-99 328.1 0.2 2.1e-61 205.9 0.1 2.6 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 KUM66636.1 - 1.4e-77 258.5 2.1 4.1e-77 257.0 1.5 1.9 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 KUM66636.1 - 8.2e-67 222.9 0.2 1.8e-66 221.9 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 Hom_end_hint PF05203.11 KUM66636.1 - 8.7e-50 169.4 9.7 1.3e-31 110.0 0.0 3.3 2 1 1 3 3 3 2 Hom_end-associated Hint PROCT PF08084.6 KUM66636.1 - 3.8e-46 155.8 0.0 1.1e-45 154.3 0.0 1.9 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 KUM66636.1 - 6.6e-44 147.7 0.2 2e-43 146.1 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Hint_2 PF13403.1 KUM66636.1 - 0.0062 16.4 0.1 0.1 12.5 0.0 2.4 1 1 0 1 1 1 1 Hint domain DUF3753 PF12575.3 KUM66636.1 - 0.1 12.4 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) OCD_Mu_crystall PF02423.10 KUM66636.1 - 0.69 8.6 1.8 1.1 7.9 0.7 1.7 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family Slx4 PF09494.5 KUM66637.1 - 2.1e-28 97.8 0.0 3.8e-28 97.0 0.0 1.5 1 0 0 1 1 1 1 Slx4 endonuclease Zn_clus PF00172.13 KUM66638.1 - 9.1e-05 22.2 9.8 0.00016 21.4 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADIP PF11559.3 KUM66638.1 - 0.00019 21.3 5.1 0.00032 20.6 3.5 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 KUM66638.1 - 0.00036 20.8 1.2 0.00074 19.8 0.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF972) DUF3450 PF11932.3 KUM66638.1 - 0.00041 19.6 0.2 0.00053 19.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF904 PF06005.7 KUM66638.1 - 0.00061 20.0 6.4 0.0012 19.1 4.3 1.5 2 0 0 2 2 1 1 Protein of unknown function (DUF904) Tropomyosin_1 PF12718.2 KUM66638.1 - 0.0023 17.7 1.9 0.0039 17.0 1.3 1.3 1 0 0 1 1 1 1 Tropomyosin like TSC22 PF01166.13 KUM66638.1 - 0.0028 17.5 1.1 0.0051 16.7 0.8 1.5 1 0 0 1 1 1 1 TSC-22/dip/bun family IncA PF04156.9 KUM66638.1 - 0.0029 17.2 0.6 0.0038 16.8 0.4 1.2 1 0 0 1 1 1 1 IncA protein DivIC PF04977.10 KUM66638.1 - 0.0042 16.5 3.7 0.008 15.6 2.6 1.5 1 0 0 1 1 1 1 Septum formation initiator DUF4201 PF13870.1 KUM66638.1 - 0.0046 16.4 1.3 0.0046 16.4 0.9 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) RmuC PF02646.11 KUM66638.1 - 0.007 15.2 1.2 0.0095 14.8 0.8 1.1 1 0 0 1 1 1 1 RmuC family FliD_C PF07195.7 KUM66638.1 - 0.0097 15.2 0.9 0.013 14.8 0.6 1.2 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus DUF3186 PF11382.3 KUM66638.1 - 0.011 14.9 0.6 0.014 14.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) TMF_DNA_bd PF12329.3 KUM66638.1 - 0.013 15.2 5.7 0.023 14.5 4.0 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF3373 PF11853.3 KUM66638.1 - 0.021 13.3 0.2 0.024 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) SPAM PF02090.10 KUM66638.1 - 0.03 14.3 0.4 0.03 14.3 0.3 1.5 2 0 0 2 2 1 0 Salmonella surface presentation of antigen gene type M protein DUF4200 PF13863.1 KUM66638.1 - 0.031 14.2 3.6 0.05 13.5 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Myosin_tail_1 PF01576.14 KUM66638.1 - 0.032 11.9 2.2 0.047 11.4 1.5 1.2 1 0 0 1 1 1 0 Myosin tail DUF3552 PF12072.3 KUM66638.1 - 0.032 13.4 3.6 0.051 12.7 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) FlaC_arch PF05377.6 KUM66638.1 - 0.034 14.0 1.0 0.065 13.1 0.7 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Prefoldin PF02996.12 KUM66638.1 - 0.037 13.6 4.4 0.052 13.1 3.1 1.2 1 0 0 1 1 1 0 Prefoldin subunit bZIP_2 PF07716.10 KUM66638.1 - 0.04 13.7 10.5 0.085 12.6 7.3 1.5 1 0 0 1 1 1 0 Basic region leucine zipper BLOC1_2 PF10046.4 KUM66638.1 - 0.055 13.6 2.3 0.085 13.0 1.6 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.6 KUM66638.1 - 0.059 13.2 1.2 0.09 12.6 0.8 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) V_ATPase_I PF01496.14 KUM66638.1 - 0.09 10.6 0.1 0.095 10.5 0.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SseC PF04888.7 KUM66638.1 - 0.1 11.9 1.2 0.12 11.6 0.8 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Spc24 PF08286.6 KUM66638.1 - 0.13 11.9 2.6 0.2 11.3 1.8 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 AKNA PF12443.3 KUM66638.1 - 0.13 12.3 6.8 0.19 11.7 4.6 1.5 1 1 0 1 1 1 0 AT-hook-containing transcription factor Snapin_Pallidin PF14712.1 KUM66638.1 - 0.14 12.4 5.4 0.15 12.4 2.3 1.9 2 0 0 2 2 2 0 Snapin/Pallidin CENP-H PF05837.7 KUM66638.1 - 0.15 12.2 3.7 0.3 11.2 2.6 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) PspA_IM30 PF04012.7 KUM66638.1 - 0.16 11.2 5.9 0.28 10.5 4.1 1.3 1 0 0 1 1 1 0 PspA/IM30 family bZIP_1 PF00170.16 KUM66638.1 - 0.21 11.5 4.2 0.52 10.3 2.9 1.7 1 0 0 1 1 1 0 bZIP transcription factor DUF3847 PF12958.2 KUM66638.1 - 0.24 11.2 4.9 0.52 10.1 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) Synaptobrevin PF00957.16 KUM66638.1 - 0.29 10.7 2.2 0.58 9.7 1.3 1.5 2 0 0 2 2 1 0 Synaptobrevin Osmo_CC PF08946.5 KUM66638.1 - 0.92 9.5 5.4 1.5 8.8 3.8 1.4 1 0 0 1 1 1 0 Osmosensory transporter coiled coil DUF3251 PF11622.3 KUM66638.1 - 1.2 8.4 5.6 2 7.8 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) bZIP_Maf PF03131.12 KUM66638.1 - 9.2 6.6 10.0 0.52 10.6 2.7 2.0 3 0 0 3 3 2 0 bZIP Maf transcription factor TPR_11 PF13414.1 KUM66640.1 - 7.6e-10 38.2 0.4 9.7e-08 31.5 0.0 2.8 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 KUM66640.1 - 9.6e-07 28.2 3.7 0.012 15.4 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 KUM66640.1 - 3.3e-06 26.4 3.8 0.00012 21.4 0.0 3.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 KUM66640.1 - 2.2e-05 24.6 0.0 0.38 11.5 0.0 3.3 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KUM66640.1 - 0.0066 16.2 0.9 0.2 11.5 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KUM66640.1 - 0.0088 16.1 0.6 0.2 11.7 0.1 3.0 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KUM66640.1 - 0.052 14.0 0.1 21 5.8 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KUM66640.1 - 0.094 13.4 0.3 9.8 6.9 0.0 3.3 2 1 2 4 4 4 0 Tetratricopeptide repeat Type_III_YscX PF09474.5 KUM66640.1 - 0.1 12.6 1.2 0.84 9.6 0.1 2.5 2 0 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) YfiO PF13525.1 KUM66640.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Outer membrane lipoprotein Cut8_M PF14483.1 KUM66640.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Cut8 dimerisation domain TPR_8 PF13181.1 KUM66640.1 - 1.1 9.2 0.0 1.1 9.2 0.0 2.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KUM66641.1 - 0.12 12.3 0.4 0.42 10.5 0.1 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat Methyltransf_23 PF13489.1 KUM66642.1 - 7.8e-16 58.2 0.1 2.1e-15 56.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM66642.1 - 3.9e-08 33.8 0.0 5.6e-07 30.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM66642.1 - 0.00021 21.6 0.0 0.0044 17.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM66642.1 - 0.00055 20.3 0.0 0.0025 18.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KUM66642.1 - 0.00066 19.6 0.0 0.0016 18.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KUM66642.1 - 0.00076 18.5 0.0 0.0027 16.7 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_31 PF13847.1 KUM66642.1 - 0.0017 17.9 0.0 0.0073 15.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KUM66642.1 - 0.019 14.3 0.0 0.11 11.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_25 PF13649.1 KUM66642.1 - 0.021 15.1 0.0 0.22 11.8 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 KUM66642.1 - 0.075 12.1 0.0 1.9 7.5 0.0 2.4 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family NAD_binding_4 PF07993.7 KUM66643.1 - 4.2e-37 127.4 0.0 6.6e-37 126.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KUM66643.1 - 1.5e-29 102.6 0.1 2.8e-29 101.7 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KUM66643.1 - 2.3e-10 40.3 0.1 7.9e-10 38.5 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KUM66643.1 - 3.7e-09 36.7 0.2 8e-09 35.6 0.1 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 KUM66643.1 - 0.0051 16.7 2.3 0.015 15.2 1.2 2.2 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KUM66643.1 - 0.0085 15.7 0.5 0.0085 15.7 0.4 2.0 2 1 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KUM66643.1 - 0.013 15.5 1.6 0.67 9.9 0.3 3.3 3 0 0 3 3 3 0 NADH(P)-binding 3Beta_HSD PF01073.14 KUM66643.1 - 0.15 10.7 0.0 1.5 7.4 0.0 2.1 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NB-ARC PF00931.17 KUM66643.1 - 0.33 9.7 0.0 12 4.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Aldo_ket_red PF00248.16 KUM66644.1 - 5.6e-47 159.9 0.0 6.9e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PDDEXK_1 PF12705.2 KUM66646.1 - 0.0047 16.3 0.0 0.009 15.4 0.0 1.5 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily HEAT PF02985.17 KUM66646.1 - 0.042 13.9 0.0 0.19 11.8 0.0 2.2 1 0 0 1 1 1 0 HEAT repeat Fungal_trans PF04082.13 KUM66649.1 - 1.6e-27 96.0 0.0 2.8e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM66649.1 - 1.5e-05 24.7 8.1 1.5e-05 24.7 5.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KUM66650.1 - 4.1e-40 137.5 28.5 8.4e-40 136.5 19.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Fe-S_assembly PF04384.8 KUM66650.1 - 0.14 12.5 0.2 0.26 11.6 0.1 1.4 1 0 0 1 1 1 0 Iron-sulphur cluster assembly PH PF00169.24 KUM66652.1 - 2.8e-11 43.5 0.0 8e-11 42.0 0.0 1.8 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.1 KUM66652.1 - 7.3e-08 31.8 0.0 1.4e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.12 KUM66652.1 - 9.8e-08 31.7 0.1 1.7e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.23 KUM66652.1 - 8.8e-07 28.2 0.1 1.8e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain PH_11 PF15413.1 KUM66652.1 - 3.4e-06 27.2 0.0 9.5e-06 25.8 0.0 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain SAM_1 PF00536.25 KUM66652.1 - 0.016 15.3 0.1 0.032 14.3 0.1 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Ribosomal_L14 PF00238.14 KUM66653.1 - 3.1e-33 114.1 0.0 3.5e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Metallophos PF00149.23 KUM66654.1 - 3.3e-09 36.4 3.9 9.8e-09 34.8 2.7 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase NIF PF03031.13 KUM66655.1 - 7.3e-40 136.2 0.1 1e-39 135.7 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 KUM66655.1 - 0.078 13.2 0.3 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF2893 PF11459.3 KUM66656.1 - 0.014 15.1 0.0 0.043 13.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknwon function (DUF2893) F-box PF00646.28 KUM66656.1 - 0.13 11.9 0.1 5.8 6.6 0.1 2.4 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 KUM66656.1 - 0.19 11.5 0.8 0.62 9.8 0.1 2.2 2 1 0 2 2 2 0 F-box-like TFIIIC_delta PF12657.2 KUM66657.1 - 0.0052 16.5 0.0 0.02 14.6 0.0 2.0 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term EspF PF04806.7 KUM66657.1 - 0.0064 16.6 3.7 0.022 14.9 2.6 1.9 1 0 0 1 1 1 1 EspF protein repeat F-box PF00646.28 KUM66657.1 - 0.033 13.8 0.0 0.084 12.5 0.0 1.7 1 0 0 1 1 1 0 F-box domain Fungal_trans PF04082.13 KUM66658.1 - 7.4e-20 70.8 0.1 2.6e-19 69.1 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM66658.1 - 1e-06 28.5 6.9 2.3e-06 27.4 4.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 KUM66661.1 - 2.3e-25 89.2 0.0 8.2e-25 87.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM66661.1 - 1.2e-10 40.8 1.3 6.2e-05 22.1 0.0 3.5 3 1 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 KUM66661.1 - 0.00069 18.6 0.0 0.83 8.5 0.0 3.1 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 KUM66661.1 - 0.0015 18.2 0.1 0.0094 15.7 0.1 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family eIF-1a PF01176.14 KUM66662.1 - 1.9e-14 52.8 0.3 3.3e-14 52.0 0.2 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DUF1434 PF07254.7 KUM66662.1 - 0.15 11.9 0.2 0.25 11.1 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1434) Sugar_tr PF00083.19 KUM66663.1 - 3e-105 352.4 26.4 3.9e-105 352.0 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM66663.1 - 1e-15 57.3 37.0 1.7e-08 33.5 8.7 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily Metallophos PF00149.23 KUM66665.1 - 3.2e-36 124.6 0.3 2.3e-29 102.2 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase DUF3628 PF12300.3 KUM66666.1 - 0.026 14.5 0.2 0.034 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) NSP2-B_epitope PF14757.1 KUM66666.1 - 0.033 13.6 0.3 0.044 13.2 0.2 1.1 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein ALG3 PF05208.8 KUM66667.1 - 5.2e-121 404.3 16.8 6.4e-121 404.0 11.7 1.0 1 0 0 1 1 1 1 ALG3 protein DUF4381 PF14316.1 KUM66668.1 - 0.082 13.0 0.1 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TPR_2 PF07719.12 KUM66669.1 - 7.7e-14 50.4 6.2 0.0026 17.5 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 KUM66669.1 - 2.2e-13 49.6 3.5 0.00014 21.4 0.0 4.7 3 1 1 4 4 4 3 TPR repeat TPR_1 PF00515.23 KUM66669.1 - 1.5e-09 37.0 1.1 0.043 13.4 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 KUM66669.1 - 1e-07 31.8 6.6 0.026 14.4 0.7 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KUM66669.1 - 4.4e-07 30.3 18.6 0.0009 19.8 1.3 6.1 5 3 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KUM66669.1 - 1.8e-06 28.1 7.2 0.1 12.9 0.0 5.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 KUM66669.1 - 0.00011 21.7 0.0 5 7.1 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.9 KUM66669.1 - 0.00025 21.1 10.3 0.8 10.3 1.1 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 KUM66669.1 - 0.001 19.0 0.0 17 5.9 0.0 4.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KUM66669.1 - 0.0013 19.2 16.0 2.7 8.8 1.0 8.0 8 1 1 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.1 KUM66669.1 - 0.0049 16.5 7.4 13 5.8 0.3 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Apc3 PF12895.2 KUM66669.1 - 0.019 15.0 0.9 1.1 9.4 0.0 3.1 2 1 1 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR_3 PF13812.1 KUM66669.1 - 0.072 13.4 4.1 0.083 13.2 0.3 3.1 3 0 0 3 3 2 0 Pentatricopeptide repeat domain Ofd1_CTDD PF10637.4 KUM66669.1 - 0.088 11.9 0.1 4.7 6.2 0.0 2.1 2 0 0 2 2 2 0 Oxoglutarate and iron-dependent oxygenase degradation C-term DUF3337 PF11816.3 KUM66670.1 - 3e-93 312.8 0.0 4.2e-90 302.5 0.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 KUM66670.1 - 2.2e-25 87.5 16.1 1.7e-08 34.0 0.1 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Phageshock_PspG PF09583.5 KUM66671.1 - 0.4 10.7 3.1 0.58 10.2 2.2 1.2 1 0 0 1 1 1 0 Phage shock protein G (Phageshock_PspG) EF-hand_6 PF13405.1 KUM66672.1 - 7.6e-09 34.7 0.4 0.0022 17.7 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 KUM66672.1 - 0.0018 17.4 0.0 0.0057 15.8 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 KUM66672.1 - 0.0094 16.0 2.5 0.085 13.0 0.5 3.0 1 1 0 2 2 2 1 EF-hand domain pair WD40 PF00400.27 KUM66673.1 - 0.00024 20.8 0.1 0.15 11.9 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat CNH PF00780.17 KUM66673.1 - 0.00037 20.0 0.1 0.011 15.1 0.1 2.4 2 0 0 2 2 2 1 CNH domain Coatomer_WDAD PF04053.9 KUM66673.1 - 0.00087 18.1 0.0 0.003 16.4 0.0 1.9 2 0 0 2 2 2 1 Coatomer WD associated region Hira PF07569.6 KUM66673.1 - 0.02 14.0 0.1 0.086 12.0 0.0 2.0 3 0 0 3 3 3 0 TUP1-like enhancer of split DNA_gyraseA_C PF03989.8 KUM66673.1 - 0.057 12.7 0.0 0.51 9.6 0.0 2.2 2 0 0 2 2 2 0 DNA gyrase C-terminal domain, beta-propeller Apc4_WD40 PF12894.2 KUM66673.1 - 0.12 11.9 0.0 6.8 6.2 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain OB_NTP_bind PF07717.11 KUM66674.1 - 3.6e-29 100.9 0.1 1.2e-28 99.2 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KUM66674.1 - 1.1e-23 83.1 0.0 2.9e-23 81.8 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KUM66674.1 - 7.9e-11 41.6 0.0 1.8e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KUM66674.1 - 3e-06 26.8 0.2 7.1e-06 25.6 0.2 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KUM66674.1 - 0.00025 21.1 0.1 0.0009 19.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 KUM66674.1 - 0.0011 18.4 0.3 0.003 17.0 0.2 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SE PF00437.15 KUM66674.1 - 0.011 14.7 0.0 0.021 13.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 KUM66674.1 - 0.092 12.3 0.0 0.37 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KUM66674.1 - 0.098 12.9 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Flavi_DEAD PF07652.9 KUM66674.1 - 0.12 12.1 0.1 0.32 10.7 0.1 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_29 PF13555.1 KUM66674.1 - 0.18 11.3 0.0 0.51 9.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SAP18 PF06487.7 KUM66675.1 - 0.0027 17.4 0.1 0.0075 16.0 0.1 1.7 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) TPR_14 PF13428.1 KUM66675.1 - 0.01 16.3 1.2 7.5 7.4 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3573 PF12097.3 KUM66675.1 - 0.19 10.2 0.7 0.53 8.8 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) Lipase_3 PF01764.20 KUM66676.1 - 3.4e-36 123.9 0.0 4.9e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.11 KUM66676.1 - 5.5e-23 80.5 0.3 1.3e-22 79.4 0.2 1.7 1 0 0 1 1 1 1 Lipase 3 N-terminal region Abhydrolase_5 PF12695.2 KUM66676.1 - 5.9e-05 22.8 0.0 8.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 KUM66676.1 - 7.2e-05 22.6 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.2 KUM66676.1 - 9.7e-05 22.3 0.1 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 KUM66676.1 - 0.00044 19.7 0.0 0.00084 18.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase Thioesterase PF00975.15 KUM66676.1 - 0.0021 18.3 0.0 0.0032 17.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PE-PPE PF08237.6 KUM66676.1 - 0.0078 15.6 0.2 0.018 14.4 0.1 1.7 1 1 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.15 KUM66676.1 - 0.0092 15.5 0.1 0.044 13.3 0.0 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold DUF2974 PF11187.3 KUM66676.1 - 0.018 14.4 0.6 0.16 11.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Ser_hydrolase PF06821.8 KUM66676.1 - 0.037 13.6 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_3 PF07859.8 KUM66676.1 - 0.039 13.5 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 KUM66676.1 - 0.043 13.2 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF676 PF05057.9 KUM66676.1 - 0.069 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PRMT5 PF05185.11 KUM66677.1 - 1.3e-168 561.5 0.0 1.8e-168 561.1 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase DUF4661 PF15576.1 KUM66678.1 - 2.6 7.6 5.2 3.1 7.3 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Peptidase_S10 PF00450.17 KUM66679.1 - 1.4e-91 307.7 3.2 1.7e-91 307.4 2.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DSPc PF00782.15 KUM66680.1 - 4.1e-29 100.8 0.0 4.2e-21 74.9 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KUM66680.1 - 5.9e-06 25.7 0.0 0.00038 19.8 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DNA_mis_repair PF01119.14 KUM66681.1 - 2.6e-33 113.9 0.2 4.3e-33 113.2 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KUM66681.1 - 8.3e-16 57.8 0.0 2e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KUM66681.1 - 3.2e-11 42.9 0.0 7.5e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DHC_N1 PF08385.7 KUM66682.1 - 8.3e-185 615.5 5.9 8.3e-185 615.5 4.1 4.9 8 0 0 8 8 7 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 KUM66682.1 - 3.5e-128 427.6 7.2 3.5e-128 427.6 5.0 4.3 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 KUM66682.1 - 1e-106 357.6 0.0 2.8e-106 356.2 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 KUM66682.1 - 3.8e-77 258.9 0.0 1.1e-76 257.4 0.0 1.8 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 KUM66682.1 - 2.6e-43 147.4 0.9 7.6e-43 145.9 0.0 2.3 3 0 0 3 3 3 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 KUM66682.1 - 1.4e-40 138.9 0.0 8.8e-40 136.3 0.0 2.2 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 KUM66682.1 - 2.8e-40 138.1 5.8 2.8e-40 138.1 4.0 1.6 2 0 0 2 2 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 KUM66682.1 - 1.4e-30 105.8 0.4 1.1e-09 38.1 0.0 6.3 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 KUM66682.1 - 1.4e-19 70.2 0.1 8.6e-19 67.6 0.0 2.4 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 AAA PF00004.24 KUM66682.1 - 7.4e-15 55.3 0.0 7.2e-05 22.9 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KUM66682.1 - 3.8e-14 52.9 0.0 0.0075 16.4 0.0 6.1 5 0 0 5 5 4 3 AAA domain AAA_33 PF13671.1 KUM66682.1 - 8.9e-09 35.3 0.4 0.37 10.6 0.1 5.1 4 0 0 4 4 4 3 AAA domain AAA_18 PF13238.1 KUM66682.1 - 2.9e-08 34.0 1.7 0.019 15.2 0.0 5.0 5 0 0 5 5 4 2 AAA domain AAA_17 PF13207.1 KUM66682.1 - 4.9e-08 33.8 0.1 0.04 14.7 0.0 5.6 4 0 0 4 4 4 1 AAA domain T2SE PF00437.15 KUM66682.1 - 5.1e-07 28.8 0.0 0.026 13.4 0.0 4.0 4 0 0 4 4 4 2 Type II/IV secretion system protein ABC_tran PF00005.22 KUM66682.1 - 5.6e-06 26.7 0.1 0.88 9.8 0.1 4.8 3 0 0 3 3 3 2 ABC transporter AAA_16 PF13191.1 KUM66682.1 - 8.4e-06 25.8 9.3 0.098 12.6 0.1 7.9 7 1 1 8 8 8 1 AAA ATPase domain AAA_29 PF13555.1 KUM66682.1 - 2.5e-05 23.7 0.0 2 7.9 0.0 3.8 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_19 PF13245.1 KUM66682.1 - 2.9e-05 23.7 0.2 0.43 10.3 0.0 4.4 4 0 0 4 4 4 1 Part of AAA domain Zeta_toxin PF06414.7 KUM66682.1 - 3.3e-05 23.0 0.2 0.44 9.6 0.0 3.9 4 0 0 4 4 3 2 Zeta toxin Mg_chelatase PF01078.16 KUM66682.1 - 0.00018 20.7 0.9 0.44 9.6 0.0 3.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 KUM66682.1 - 0.0016 17.6 0.0 6 6.0 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 KUM66682.1 - 0.013 15.6 0.2 32 4.7 0.0 4.5 4 0 0 4 4 4 0 RNA helicase AAA_25 PF13481.1 KUM66682.1 - 0.021 14.2 1.3 0.48 9.7 0.0 3.4 4 0 0 4 4 3 0 AAA domain DUF3762 PF12591.3 KUM66682.1 - 0.14 12.2 0.1 0.62 10.1 0.0 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF3762) His_leader PF08047.6 KUM66682.1 - 2.7 7.4 1.5 7.3 6.1 1.0 1.8 1 0 0 1 1 1 0 Histidine operon leader peptide Svf1 PF08622.5 KUM66683.1 - 5.3e-128 426.5 0.5 2.6e-64 217.2 0.1 2.1 1 1 1 2 2 2 2 Svf1-like CrtC PF07143.6 KUM66683.1 - 0.0075 15.6 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) Ribosomal_L11_N PF03946.9 KUM66684.1 - 1.5e-26 91.5 0.1 3.1e-26 90.5 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KUM66684.1 - 2.9e-23 81.7 0.0 4.9e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Pkinase PF00069.20 KUM66685.1 - 2.5e-57 194.0 0.0 1e-56 192.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM66685.1 - 3.9e-19 68.7 0.0 1e-18 67.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KUM66685.1 - 0.023 14.4 0.4 0.048 13.4 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mito_carr PF00153.22 KUM66686.1 - 1.6e-42 143.1 2.8 6.6e-15 54.5 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein AMP-binding PF00501.23 KUM66689.1 - 1.9e-160 533.8 0.0 7.4e-83 278.2 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KUM66689.1 - 5e-61 206.1 0.6 4.2e-24 84.9 0.0 3.7 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.20 KUM66689.1 - 5.2e-14 52.2 1.6 9.6e-06 25.7 0.1 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KUM66689.1 - 2.9e-13 50.5 0.0 9.2e-07 29.7 0.0 2.9 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain MatE PF01554.13 KUM66690.1 - 1.1e-41 142.1 34.8 4e-26 91.5 6.5 2.5 3 0 0 3 3 3 2 MatE TFCD_C PF12612.3 KUM66692.1 - 1.9e-10 40.4 0.0 7.1e-10 38.6 0.0 1.8 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 KUM66693.1 - 0.00095 19.0 7.5 0.92 9.7 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.1 KUM66693.1 - 0.0032 17.7 6.2 3.2 8.1 0.1 5.0 4 1 1 5 5 5 3 HEAT repeats TFCD_C PF12612.3 KUM66693.1 - 0.0037 16.7 0.1 0.12 11.8 0.1 3.0 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal IFRD PF05004.8 KUM66693.1 - 0.0062 15.6 0.8 0.0062 15.6 0.5 1.8 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.1 KUM66693.1 - 1.3 9.5 18.6 4.7 7.8 0.0 7.1 9 0 0 9 9 9 0 HEAT-like repeat Glyco_hydro_18 PF00704.23 KUM66694.1 - 4.9e-53 180.7 7.2 4.5e-51 174.3 2.9 2.4 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 LysM PF01476.15 KUM66694.1 - 9.6e-09 34.9 1.1 0.00061 19.6 0.2 2.7 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 KUM66694.1 - 9.9e-07 28.6 5.4 9.9e-07 28.6 3.8 3.3 3 0 0 3 3 3 1 Chitin recognition protein Complex1_30kDa PF00329.14 KUM66695.1 - 0.063 13.5 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 30 Kd subunit FAM220 PF15487.1 KUM66696.1 - 0.15 11.3 0.3 0.19 11.0 0.2 1.1 1 0 0 1 1 1 0 FAM220 family Pkinase PF00069.20 KUM66697.1 - 1.4e-61 207.9 0.0 2.1e-61 207.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM66697.1 - 5.6e-35 120.6 0.0 9.4e-35 119.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 KUM66697.1 - 1.4e-33 114.4 14.1 2.5e-19 68.7 2.9 2.6 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 KUM66697.1 - 7.7e-21 73.5 29.0 1.3e-11 44.0 6.6 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 KUM66697.1 - 2.1e-14 53.7 3.3 6.6e-14 52.1 2.3 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KUM66697.1 - 0.042 12.8 0.0 0.072 12.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Peptidase_M6 PF05547.6 KUM66697.1 - 0.14 10.1 0.3 0.7 7.8 0.0 1.9 2 0 0 2 2 2 0 Immune inhibitor A peptidase M6 DUF605 PF04652.11 KUM66697.1 - 0.22 10.8 22.4 0.5 9.7 15.5 1.5 1 0 0 1 1 1 0 Vta1 like Uds1 PF15456.1 KUM66697.1 - 1.2 9.0 5.6 0.26 11.3 0.6 2.2 2 0 0 2 2 2 0 Up-regulated During Septation Ank_2 PF12796.2 KUM66699.1 - 5.7e-38 129.1 0.0 1.1e-12 48.0 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KUM66699.1 - 5.7e-32 107.9 0.0 1.6e-05 24.4 0.0 6.5 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.1 KUM66699.1 - 9.1e-26 87.3 0.0 0.0004 20.3 0.0 6.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 KUM66699.1 - 5.5e-24 84.0 0.0 1e-06 29.0 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM66699.1 - 8e-23 79.9 0.3 3.7e-06 27.0 0.0 5.8 2 2 4 6 6 6 5 Ankyrin repeats (many copies) PsbY PF06298.6 KUM66699.1 - 0.021 14.3 0.9 40 3.8 0.0 4.1 4 0 0 4 4 4 0 Photosystem II protein Y (PsbY) Fungal_trans PF04082.13 KUM66701.1 - 4.9e-42 143.6 0.3 9.4e-42 142.6 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM66701.1 - 3.9e-08 33.0 8.2 7.8e-08 32.1 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.24 KUM66701.1 - 0.0072 15.9 4.1 0.0072 15.9 2.8 1.8 2 0 0 2 2 2 1 PHD-finger DUF3473 PF11959.3 KUM66701.1 - 0.042 13.2 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3473) Prok-RING_1 PF14446.1 KUM66701.1 - 1.1 9.0 9.0 2.1 8.1 6.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Beta-lactamase PF00144.19 KUM66703.1 - 1.1e-48 165.9 0.0 1.6e-48 165.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 KUM66703.1 - 9.4e-08 31.8 0.0 1.8e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) DUF1029 PF06269.7 KUM66704.1 - 0.058 13.4 1.4 0.17 11.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1029) SARS_3b PF12383.3 KUM66704.1 - 0.063 13.2 0.5 0.2 11.5 0.1 2.0 1 1 1 2 2 2 0 Severe acute respiratory syndrome coronavirus 3b protein Abhydrolase_5 PF12695.2 KUM66705.1 - 9.1e-06 25.4 0.0 1.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 KUM66705.1 - 0.00027 20.2 0.0 0.00051 19.3 0.0 1.5 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KUM66705.1 - 0.024 13.8 0.4 0.062 12.5 0.3 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 KUM66705.1 - 0.041 13.4 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold RhoGEF PF00621.15 KUM66707.1 - 2.8e-23 82.7 0.0 1.4e-22 80.4 0.0 2.0 2 0 0 2 2 2 1 RhoGEF domain DUF3507 PF12015.3 KUM66707.1 - 4.1e-06 26.4 0.0 7.6e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) RhoGAP PF00620.22 KUM66707.1 - 0.074 12.6 0.0 0.98 9.0 0.0 2.7 2 0 0 2 2 2 0 RhoGAP domain ATP_bind_3 PF01171.15 KUM66708.1 - 3.9e-37 127.5 0.0 6.4e-26 90.9 0.0 2.4 2 1 0 2 2 2 2 PP-loop family Asn_synthase PF00733.16 KUM66708.1 - 0.053 13.0 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase Fungal_trans PF04082.13 KUM66709.1 - 0.0029 16.5 0.2 0.0036 16.2 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM66710.1 - 4.8e-08 32.7 10.3 7.6e-08 32.1 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.17 KUM66711.1 - 6.7e-25 86.5 0.5 2.5e-11 43.0 0.4 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM66711.1 - 1.7e-16 59.9 0.0 5.9e-07 29.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM66711.1 - 3.4e-15 55.6 0.0 1.3e-08 34.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MCM2_N PF12619.3 KUM66711.1 - 0.0029 17.5 0.1 0.0046 16.9 0.1 1.2 1 0 0 1 1 1 1 Mini-chromosome maintenance protein 2 Limkain-b1 PF11608.3 KUM66711.1 - 0.017 14.8 0.0 0.047 13.4 0.0 1.7 1 0 0 1 1 1 0 Limkain b1 ATP-synt_D PF01813.12 KUM66712.1 - 7.3e-58 195.3 2.8 6.5e-52 175.9 0.3 2.2 2 0 0 2 2 2 2 ATP synthase subunit D ERM PF00769.14 KUM66712.1 - 0.89 9.0 9.4 0.14 11.6 3.1 1.9 2 0 0 2 2 2 0 Ezrin/radixin/moesin family TPR_14 PF13428.1 KUM66713.1 - 1.1e-12 47.3 14.3 0.42 11.3 0.0 11.8 11 2 2 14 14 13 2 Tetratricopeptide repeat TPR_12 PF13424.1 KUM66713.1 - 7.6e-11 41.8 3.8 0.031 14.2 0.0 7.4 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 KUM66713.1 - 8.1e-11 42.1 0.3 0.049 13.9 0.0 6.5 5 1 1 6 6 6 2 Tetratricopeptide repeat Suf PF05843.9 KUM66713.1 - 6.4e-09 35.9 15.6 0.0082 15.9 0.2 5.9 4 1 1 5 5 5 2 Suppressor of forked protein (Suf) TPR_11 PF13414.1 KUM66713.1 - 5.6e-08 32.3 9.7 0.006 16.2 0.0 7.0 8 1 0 8 8 7 2 TPR repeat Mad3_BUB1_I PF08311.7 KUM66713.1 - 1.8e-07 30.9 9.2 0.82 9.4 0.1 6.6 6 0 0 6 6 6 1 Mad3/BUB1 homology region 1 TPR_8 PF13181.1 KUM66713.1 - 1.2e-06 27.8 3.5 0.18 11.6 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 KUM66713.1 - 1.4e-06 27.5 7.1 0.00068 18.7 1.0 4.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 KUM66713.1 - 1.8e-06 28.4 6.0 0.046 14.4 0.0 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 KUM66713.1 - 2.3e-06 27.1 18.8 0.88 9.6 0.0 8.6 10 0 0 10 10 9 2 Tetratricopeptide repeat SNAP PF14938.1 KUM66713.1 - 1.6e-05 24.1 1.5 0.014 14.5 0.1 4.5 4 1 0 4 4 4 1 Soluble NSF attachment protein, SNAP NRDE-2 PF08424.5 KUM66713.1 - 0.00015 20.7 8.7 0.1 11.4 0.5 4.4 2 2 2 4 4 4 2 NRDE-2, necessary for RNA interference TPR_7 PF13176.1 KUM66713.1 - 0.0025 17.4 10.0 11 6.1 0.0 8.3 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_17 PF13431.1 KUM66713.1 - 0.018 15.1 10.5 0.064 13.4 0.0 5.9 8 0 0 8 8 6 0 Tetratricopeptide repeat CKAP2_C PF15297.1 KUM66713.1 - 0.032 13.0 0.1 0.078 11.7 0.1 1.6 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus TPR_6 PF13174.1 KUM66713.1 - 0.043 14.2 12.1 0.73 10.4 0.0 7.4 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_4 PF07721.9 KUM66713.1 - 0.11 13.0 3.5 21 5.9 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat HAT PF02184.11 KUM66713.1 - 0.14 11.9 4.9 2.5 7.9 0.0 5.3 7 0 0 7 7 4 0 HAT (Half-A-TPR) repeat Sec7 PF01369.15 KUM66714.1 - 2.9e-59 199.9 0.0 5.2e-59 199.1 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KUM66714.1 - 5.1e-20 71.5 0.0 1.3e-12 47.4 0.0 3.3 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal APC2 PF08672.6 KUM66714.1 - 0.083 13.1 0.1 12 6.2 0.2 3.1 3 0 0 3 3 3 0 Anaphase promoting complex (APC) subunit 2 DUF4351 PF14261.1 KUM66714.1 - 0.2 11.5 1.1 0.79 9.6 0.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) RIO1 PF01163.17 KUM66717.1 - 5.2e-41 140.0 0.6 1.4e-29 102.7 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.6 KUM66717.1 - 8.3e-30 102.6 0.0 3.1e-29 100.8 0.0 1.9 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.18 KUM66717.1 - 1.7e-06 27.9 0.0 0.015 15.0 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KUM66717.1 - 2.6e-06 26.6 0.0 8.7e-05 21.6 0.0 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Nop14 PF04147.7 KUM66717.1 - 0.69 7.7 11.8 0.76 7.6 8.2 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 KUM66717.1 - 2.8 6.5 16.7 4.7 5.8 11.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 KUM66717.1 - 3.4 5.5 13.5 4.7 5.1 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 KUM66717.1 - 6.6 6.2 12.8 1.8 8.1 6.6 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region NOA36 PF06524.7 KUM66717.1 - 6.9 5.8 10.3 11 5.1 7.2 1.2 1 0 0 1 1 1 0 NOA36 protein PC_rep PF01851.17 KUM66718.1 - 4.5e-19 67.5 17.4 4.7e-05 23.3 0.1 8.4 10 0 0 10 10 10 4 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KUM66718.1 - 0.00017 21.8 1.7 0.82 9.9 0.0 4.1 3 1 1 4 4 4 3 HEAT repeats TPR_5 PF12688.2 KUM66718.1 - 0.032 14.2 1.0 4.1 7.4 0.0 3.5 3 1 0 4 4 4 0 Tetratrico peptide repeat DUF2776 PF10951.3 KUM66718.1 - 0.15 11.0 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2776) Lon_C PF05362.8 KUM66719.1 - 4.4e-70 235.1 0.2 1.3e-69 233.6 0.1 1.8 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 KUM66719.1 - 3.3e-27 95.4 0.0 7e-27 94.4 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 KUM66719.1 - 3.6e-23 82.2 0.0 1.4e-22 80.3 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 KUM66719.1 - 2.8e-08 33.2 0.1 2.3e-07 30.3 0.0 2.3 2 1 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 KUM66719.1 - 4.4e-08 32.9 0.0 1.3e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KUM66719.1 - 9.5e-07 28.9 0.2 5.6e-06 26.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_3 PF07726.6 KUM66719.1 - 1.9e-05 24.2 0.0 5.2e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 KUM66719.1 - 2.4e-05 23.2 0.1 0.00019 20.2 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus AAA_17 PF13207.1 KUM66719.1 - 3.7e-05 24.5 0.0 0.00015 22.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KUM66719.1 - 6.5e-05 22.6 0.0 0.00018 21.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KUM66719.1 - 0.00019 21.5 0.0 0.0023 18.0 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KUM66719.1 - 0.00041 20.2 0.0 0.00099 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KUM66719.1 - 0.00047 19.2 0.0 0.0017 17.4 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 KUM66719.1 - 0.00047 20.1 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 KUM66719.1 - 0.00088 18.7 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 KUM66719.1 - 0.0018 18.1 0.0 0.0051 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KUM66719.1 - 0.003 16.6 0.0 0.0062 15.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 KUM66719.1 - 0.0081 16.4 1.2 0.11 12.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_11 PF13086.1 KUM66719.1 - 0.0094 15.5 0.1 0.21 11.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 KUM66719.1 - 0.014 14.5 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Arch_ATPase PF01637.13 KUM66719.1 - 0.018 14.7 0.0 1 9.0 0.0 2.8 2 1 0 3 3 2 0 Archaeal ATPase CCDC-167 PF15188.1 KUM66719.1 - 0.02 14.8 3.2 0.061 13.2 0.6 2.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 AAA_25 PF13481.1 KUM66719.1 - 0.021 14.2 0.0 0.058 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KUM66719.1 - 0.03 14.4 0.0 0.26 11.4 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.1 KUM66719.1 - 0.039 14.2 3.2 0.29 11.4 0.0 2.9 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 KUM66719.1 - 0.044 13.5 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.16 KUM66719.1 - 0.05 12.7 0.1 0.11 11.5 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_PrkA PF08298.6 KUM66719.1 - 0.071 11.7 0.0 0.43 9.2 0.0 2.0 2 0 0 2 2 2 0 PrkA AAA domain AAA_30 PF13604.1 KUM66719.1 - 0.076 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KUM66719.1 - 0.086 12.4 0.1 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KUM66719.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KUM66719.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Mcm10 PF09332.6 KUM66719.1 - 0.15 11.3 0.3 0.25 10.6 0.2 1.2 1 0 0 1 1 1 0 Mcm10 replication factor Ribosomal_L23 PF00276.15 KUM66720.1 - 1.8e-12 47.0 0.0 3.3e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 TAP42 PF04177.7 KUM66721.1 - 3.5e-78 262.9 0.1 3.9e-78 262.7 0.1 1.0 1 0 0 1 1 1 1 TAP42-like family Porphobil_deam PF01379.15 KUM66722.1 - 8.5e-77 256.8 0.0 1.1e-76 256.5 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 KUM66722.1 - 3.6e-17 62.2 0.3 6.7e-17 61.3 0.2 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Ribonuclease_3 PF00636.21 KUM66723.1 - 7.1e-44 148.8 0.0 1.6e-21 76.8 0.0 3.5 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KUM66723.1 - 1.2e-27 96.3 0.3 4.9e-14 52.3 0.0 4.2 3 2 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.9 KUM66723.1 - 3.3e-21 74.8 0.3 2.6e-20 72.0 0.1 2.5 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.26 KUM66723.1 - 1.6e-14 53.5 0.1 3.9e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KUM66723.1 - 1e-11 45.0 0.0 5.7e-11 42.5 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KUM66723.1 - 2.8e-10 39.9 0.0 9.3e-10 38.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.18 KUM66723.1 - 1.6e-05 23.9 0.0 2.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain dsrm PF00035.20 KUM66723.1 - 0.0094 16.5 0.4 3.1 8.4 0.0 2.8 2 0 0 2 2 2 1 Double-stranded RNA binding motif DUF2075 PF09848.4 KUM66723.1 - 0.039 12.9 0.0 0.081 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TAP42 PF04177.7 KUM66724.1 - 1.5e-16 60.2 0.4 1.6e-16 60.1 0.3 1.0 1 0 0 1 1 1 1 TAP42-like family Herpes_env PF01673.13 KUM66725.1 - 0.019 13.5 0.1 0.022 13.3 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein DivIC PF04977.10 KUM66725.1 - 0.85 9.1 4.6 1.9 8.0 3.2 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF972 PF06156.8 KUM66725.1 - 1 9.7 5.2 0.31 11.3 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Zn_clus PF00172.13 KUM66726.1 - 0.00023 21.0 9.4 0.00034 20.4 6.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WAK_assoc PF14380.1 KUM66726.1 - 8.2 7.0 8.2 4.8 7.7 1.2 2.3 1 1 1 2 2 2 0 Wall-associated receptor kinase C-terminal NifU_N PF01592.11 KUM66728.1 - 1.5e-51 173.6 0.0 2.5e-51 172.9 0.0 1.3 1 0 0 1 1 1 1 NifU-like N terminal domain ABC1 PF03109.11 KUM66729.1 - 1.1e-32 112.4 0.1 2e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 KUM66729.1 - 0.043 13.1 0.0 0.09 12.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family RAP1 PF07218.6 KUM66729.1 - 0.58 8.1 6.2 0.84 7.6 4.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Cu_amine_oxid PF01179.15 KUM66730.1 - 2.8e-169 563.2 0.0 3.4e-169 562.9 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KUM66730.1 - 1.3e-19 70.0 0.0 3.6e-19 68.6 0.0 1.8 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KUM66730.1 - 5e-16 58.5 0.1 8.7e-16 57.7 0.1 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DHquinase_I PF01487.10 KUM66731.1 - 1.7e-59 201.1 0.0 2.2e-59 200.8 0.0 1.1 1 0 0 1 1 1 1 Type I 3-dehydroquinase DUF974 PF06159.8 KUM66732.1 - 4.2e-76 255.6 0.0 5.1e-76 255.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) NAD_binding_8 PF13450.1 KUM66733.1 - 2.7e-16 59.3 0.0 6.7e-16 58.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KUM66733.1 - 4.8e-05 22.6 0.0 0.0052 15.9 0.0 3.0 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase DAO PF01266.19 KUM66733.1 - 0.00054 18.9 0.0 0.012 14.5 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KUM66733.1 - 0.00094 18.9 0.1 0.1 12.3 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KUM66733.1 - 0.014 14.2 0.0 0.057 12.2 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 KUM66733.1 - 0.077 12.8 0.0 0.32 10.8 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 KUM66734.1 - 1.3e-31 109.6 33.9 1.3e-31 109.6 23.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM66734.1 - 0.0011 17.6 26.3 0.014 14.0 18.2 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter Arfaptin PF06456.8 KUM66735.1 - 0.14 11.4 0.2 0.17 11.2 0.1 1.1 1 0 0 1 1 1 0 Arfaptin-like domain PRK PF00485.13 KUM66737.1 - 0.00018 21.1 0.0 0.00024 20.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 KUM66737.1 - 0.00065 20.5 0.5 0.003 18.3 0.3 2.1 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KUM66737.1 - 0.0065 15.3 0.0 0.0097 14.7 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.1 KUM66737.1 - 0.0087 16.3 0.3 0.064 13.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KUM66737.1 - 0.026 14.6 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KUM66737.1 - 0.029 13.4 0.3 0.063 12.3 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.1 KUM66737.1 - 0.04 13.8 0.1 0.58 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 KUM66737.1 - 0.066 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 KUM66737.1 - 0.072 12.8 0.3 0.17 11.6 0.2 1.7 1 1 0 1 1 1 0 Part of AAA domain FAA_hydrolase PF01557.13 KUM66739.1 - 0.00018 21.0 0.0 0.00022 20.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DPBB_1 PF03330.13 KUM66740.1 - 0.00011 22.1 0.0 0.0003 20.7 0.0 1.8 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KUM66740.1 - 0.00043 19.9 0.3 0.00043 19.9 0.2 1.7 2 0 0 2 2 2 1 Barwin family Glyco_transf_25 PF01755.12 KUM66741.1 - 0.00028 20.6 0.0 0.00048 19.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Ribonuc_red_lgC PF02867.10 KUM66742.1 - 1.6e-212 706.8 0.0 2.8e-212 706.0 0.0 1.4 2 0 0 2 2 2 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 KUM66742.1 - 5.5e-23 80.5 0.0 1.2e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 KUM66742.1 - 2.4e-15 56.7 0.0 6.9e-15 55.2 0.0 1.9 1 0 0 1 1 1 1 ATP cone domain Mur_ligase_M PF08245.7 KUM66743.1 - 3.1e-07 30.6 0.7 8.3e-07 29.2 0.5 1.7 1 1 0 1 1 1 1 Mur ligase middle domain Pkinase PF00069.20 KUM66744.1 - 2.3e-70 236.7 0.0 5.4e-70 235.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KUM66744.1 - 2.8e-50 170.8 0.0 5.7e-50 169.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KUM66744.1 - 0.0017 17.3 0.0 0.012 14.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like SPT2 PF08243.6 KUM66744.1 - 0.028 14.7 6.9 0.021 15.1 3.2 2.0 2 0 0 2 2 2 0 SPT2 chromatin protein FBP PF07299.6 KUM66744.1 - 0.25 10.6 0.8 14 4.9 0.0 2.4 2 0 0 2 2 2 0 Fibronectin-binding protein (FBP) 2-Hacid_dh_C PF02826.14 KUM66745.1 - 1.7e-44 151.0 0.0 2.5e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KUM66745.1 - 0.00011 21.6 0.0 0.00017 21.0 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ELFV_dehydrog PF00208.16 KUM66745.1 - 0.00039 20.0 0.0 0.00057 19.5 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase XdhC_C PF13478.1 KUM66745.1 - 0.0033 17.7 0.0 0.0089 16.3 0.0 1.7 2 0 0 2 2 2 1 XdhC Rossmann domain AdoHcyase_NAD PF00670.16 KUM66745.1 - 0.01 15.7 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox PF00070.22 KUM66745.1 - 0.011 16.1 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KUM66745.1 - 0.069 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Fungal_trans PF04082.13 KUM66746.1 - 4e-23 81.6 0.0 7.6e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM66746.1 - 5.2e-05 23.0 17.4 5.2e-05 23.0 12.1 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.12 KUM66746.1 - 1.7 7.4 3.9 2.7 6.7 2.7 1.2 1 0 0 1 1 1 0 Clusterin FMN_bind_2 PF04299.7 KUM66747.1 - 4.6e-44 149.8 0.0 1.4e-36 125.5 0.0 2.7 2 1 0 2 2 2 2 Putative FMN-binding domain DENN PF02141.16 KUM66748.1 - 3.5e-57 193.1 0.2 5.7e-57 192.4 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 KUM66748.1 - 1.2e-18 66.9 0.7 2.6e-18 65.8 0.5 1.6 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 KUM66748.1 - 1.5e-16 60.0 0.4 3.5e-16 58.9 0.0 1.9 2 0 0 2 2 2 1 uDENN domain C1_1 PF00130.17 KUM66748.1 - 2.9e-05 23.7 6.5 5e-05 22.9 4.5 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 KUM66748.1 - 0.0029 17.6 9.2 0.0037 17.2 2.6 2.4 2 0 0 2 2 2 1 C1-like domain SPA PF08616.5 KUM66748.1 - 0.013 15.2 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis FDF PF09532.5 KUM66748.1 - 0.056 13.9 0.1 0.19 12.2 0.0 2.0 2 0 0 2 2 2 0 FDF domain C1_2 PF03107.11 KUM66748.1 - 0.65 10.1 3.8 1.4 9.1 2.6 1.5 1 0 0 1 1 1 0 C1 domain PHD PF00628.24 KUM66748.1 - 0.69 9.6 8.7 0.15 11.7 2.8 2.0 1 1 1 2 2 2 0 PHD-finger PHD_2 PF13831.1 KUM66748.1 - 3 7.2 5.6 5.9 6.2 3.6 1.7 1 1 0 1 1 1 0 PHD-finger CENP-N PF05238.8 KUM66749.1 - 2.7e-131 438.3 0.0 3e-131 438.1 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like bZIP_2 PF07716.10 KUM66750.1 - 3.5e-13 49.1 9.5 3.5e-13 49.1 6.6 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 KUM66750.1 - 2.5e-07 30.5 5.1 4.6e-07 29.6 3.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor ATAD4 PF15321.1 KUM66750.1 - 0.16 12.9 5.6 0.18 12.7 1.9 2.3 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 DDRGK PF09756.4 KUM66750.1 - 1.1 8.6 14.7 0.12 11.7 7.3 1.5 2 0 0 2 2 2 0 DDRGK domain DUF3260 PF11658.3 KUM66750.1 - 1.3 7.0 5.0 0.15 10.2 0.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3260) CASP_C PF08172.7 KUM66752.1 - 0.023 13.7 0.9 0.029 13.4 0.6 1.1 1 0 0 1 1 1 0 CASP C terminal Methyltransf_18 PF12847.2 KUM66753.1 - 0.053 14.0 0.1 0.25 11.9 0.1 2.0 2 1 0 2 2 2 0 Methyltransferase domain TehB PF03848.9 KUM66753.1 - 0.13 11.4 0.1 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_31 PF13847.1 KUM66753.1 - 0.17 11.4 0.5 0.55 9.8 0.1 2.0 2 0 0 2 2 2 0 Methyltransferase domain HATPase_c_3 PF13589.1 KUM66755.1 - 6.5e-18 64.7 0.0 1.6e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KUM66755.1 - 2.7e-06 27.0 0.0 6e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 KUM66755.1 - 2.7e-05 23.8 0.0 0.0011 18.5 0.0 3.2 2 1 0 2 2 2 1 MutL C terminal dimerisation domain DUF2207 PF09972.4 KUM66755.1 - 0.067 11.7 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) p450 PF00067.17 KUM66757.1 - 9.9e-45 152.9 0.0 1.3e-44 152.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RasGEF PF00617.14 KUM66758.1 - 2.5e-55 187.1 0.6 5.8e-55 185.9 0.4 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KUM66758.1 - 8.1e-18 64.4 0.0 2.2e-17 63.0 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 KUM66758.1 - 2e-06 27.2 0.0 3.8e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KUM66758.1 - 2.2e-05 23.7 0.0 4.2e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain ABC2_membrane PF01061.19 KUM66759.1 - 4e-82 274.4 49.8 1.1e-45 155.4 9.9 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KUM66759.1 - 5.8e-38 130.2 0.0 9.3e-18 64.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KUM66759.1 - 1.6e-34 117.6 0.1 7.3e-31 105.8 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 KUM66759.1 - 1.3e-07 30.9 32.3 2e-05 23.7 7.8 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 KUM66759.1 - 3.7e-06 26.4 0.1 0.0038 16.6 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KUM66759.1 - 5.4e-05 23.3 0.1 0.21 11.7 0.0 3.0 2 1 0 2 2 2 2 AAA domain cobW PF02492.14 KUM66759.1 - 0.00051 19.5 0.4 0.25 10.7 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 KUM66759.1 - 0.00053 19.9 0.4 0.36 10.7 0.1 2.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KUM66759.1 - 0.00071 18.8 0.1 0.0058 15.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KUM66759.1 - 0.0008 19.4 0.4 0.21 11.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KUM66759.1 - 0.00095 19.0 0.1 1.6 8.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KUM66759.1 - 0.0019 19.0 0.0 1.1 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KUM66759.1 - 0.0019 18.4 0.0 2.3 8.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KUM66759.1 - 0.0023 17.4 0.9 0.082 12.4 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 KUM66759.1 - 0.012 15.2 0.5 3.1 7.4 0.2 2.3 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.4 KUM66759.1 - 0.019 14.4 1.4 1.6 8.1 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 KUM66759.1 - 0.028 14.1 0.0 4.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_19 PF13245.1 KUM66759.1 - 0.033 13.9 0.4 6.9 6.4 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain ABC_trans_N PF14510.1 KUM66759.1 - 0.038 14.0 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal Zeta_toxin PF06414.7 KUM66759.1 - 0.11 11.6 0.0 6.3 5.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Miro PF08477.8 KUM66759.1 - 0.11 12.9 0.0 2.1 8.8 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA PF00004.24 KUM66759.1 - 0.13 12.4 0.0 29 4.8 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 KUM66759.1 - 0.16 10.8 0.0 6.1 5.6 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein UPF0079 PF02367.12 KUM66759.1 - 0.17 11.5 0.5 5.9 6.5 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_21 PF13304.1 KUM66759.1 - 0.28 11.0 1.1 1.4 8.8 0.0 2.6 3 0 0 3 3 2 0 AAA domain AA_permease_2 PF13520.1 KUM66760.1 - 3.9e-54 183.8 49.5 4.7e-54 183.5 34.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM66760.1 - 4.3e-23 81.4 39.0 6e-23 80.9 27.0 1.2 1 0 0 1 1 1 1 Amino acid permease DUF1182 PF06681.8 KUM66760.1 - 0.16 11.1 7.9 0.13 11.4 2.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1182) DUF3353 PF11833.3 KUM66760.1 - 0.17 11.2 0.9 2.2 7.7 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) DUF3493 PF11998.3 KUM66760.1 - 0.76 9.7 0.0 0.76 9.7 0.0 2.8 2 1 2 4 4 4 0 Protein of unknown function (DUF3493) Aldedh PF00171.17 KUM66761.1 - 1.9e-183 610.0 0.4 2.2e-183 609.8 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KUM66761.1 - 0.054 12.7 0.0 0.59 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Anp1 PF03452.9 KUM66763.1 - 3.4e-108 360.8 0.0 4.3e-108 360.5 0.0 1.1 1 0 0 1 1 1 1 Anp1 Beta-lactamase PF00144.19 KUM66764.1 - 1.8e-26 92.9 0.0 2.5e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase YCII PF03795.9 KUM66765.1 - 8.2e-11 41.9 0.0 1e-10 41.6 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain Ecm33 PF12454.3 KUM66766.1 - 6.1e-14 51.6 1.3 6.1e-14 51.6 0.9 2.7 3 0 0 3 3 3 1 GPI-anchored cell wall organization protein LRR_5 PF13306.1 KUM66766.1 - 1.9e-08 34.0 0.4 0.0013 18.4 0.4 3.0 1 1 2 3 3 3 3 Leucine rich repeats (6 copies) Recep_L_domain PF01030.19 KUM66766.1 - 7.5e-07 29.1 1.7 0.11 12.4 0.0 4.7 1 1 3 4 4 4 2 Receptor L domain LRR_8 PF13855.1 KUM66766.1 - 0.25 11.1 4.5 6.8 6.5 0.0 3.4 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.2 KUM66766.1 - 2 8.1 8.3 20 4.9 3.7 4.0 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) ArsB PF02040.10 KUM66767.1 - 2.5e-11 43.2 24.9 2.1e-07 30.2 7.8 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein Sugar_tr PF00083.19 KUM66769.1 - 5e-86 289.0 24.4 5.8e-86 288.8 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM66769.1 - 1.3e-27 96.4 29.0 1.3e-27 96.4 20.1 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily Sigma_reg_N PF13800.1 KUM66769.1 - 0.11 12.5 1.1 29 4.7 0.1 3.3 3 0 0 3 3 3 0 Sigma factor regulator N-terminal COX14 PF14880.1 KUM66769.1 - 0.13 11.9 0.5 0.73 9.5 0.0 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF1129 PF06570.6 KUM66769.1 - 2.1 7.6 5.5 1.1 8.5 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF1673 PF07895.6 KUM66770.1 - 0.16 11.4 2.7 3.2 7.2 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1673) Metallophos PF00149.23 KUM66771.1 - 3.4e-11 42.9 0.7 5.9e-11 42.1 0.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KUM66771.1 - 1.1e-05 25.3 0.0 2.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MFS_1 PF07690.11 KUM66772.1 - 4.4e-12 45.3 31.3 4.4e-12 45.3 21.7 2.9 2 2 1 3 3 3 2 Major Facilitator Superfamily ELFV_dehydrog PF00208.16 KUM66773.1 - 1.3e-83 280.3 5.1 1.6e-83 280.0 3.5 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 KUM66773.1 - 5.3e-48 161.9 0.0 8.8e-48 161.1 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Med5 PF08689.5 KUM66774.1 - 0 1055.9 0.0 0 1055.6 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 Ank_2 PF12796.2 KUM66775.1 - 7.3e-91 298.6 14.6 1.9e-15 56.9 0.0 17.5 6 4 7 14 14 14 12 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KUM66775.1 - 8.5e-65 214.0 24.6 2.5e-05 24.6 0.0 23.2 17 6 9 26 26 26 16 Ankyrin repeats (many copies) Ank PF00023.25 KUM66775.1 - 3.6e-64 209.5 39.9 1.6e-06 27.6 0.0 26.6 26 2 0 26 26 26 13 Ankyrin repeat Ank_5 PF13857.1 KUM66775.1 - 5.8e-45 150.3 44.7 0.0007 19.7 0.0 21.6 16 4 5 22 22 22 13 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM66775.1 - 4.4e-44 144.0 19.5 0.00014 21.7 0.0 22.3 25 0 0 25 25 25 7 Ankyrin repeat NACHT PF05729.7 KUM66775.1 - 9.1e-09 35.1 0.1 6e-08 32.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Amidase PF01425.16 KUM66777.1 - 3e-70 237.3 0.4 5e-67 226.6 0.0 2.0 2 0 0 2 2 2 2 Amidase Pec_lyase_C PF00544.14 KUM66778.1 - 2.2e-22 79.5 5.1 3.3e-22 78.9 3.6 1.3 1 0 0 1 1 1 1 Pectate lyase Ferritin_2 PF13668.1 KUM66779.1 - 5.1e-08 32.9 0.0 8e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Sugar_tr PF00083.19 KUM66780.1 - 3.9e-81 272.9 21.1 4.5e-81 272.7 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM66780.1 - 3.3e-32 111.5 43.8 4.8e-30 104.4 16.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3624 PF12292.3 KUM66780.1 - 0.77 10.2 8.4 1.8 9.0 0.7 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3624) p450 PF00067.17 KUM66781.1 - 4.6e-58 196.8 0.0 5.5e-58 196.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fer2_3 PF13085.1 KUM66782.1 - 6.8e-32 109.5 0.0 1.1e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 KUM66782.1 - 6.3e-10 39.2 5.3 6.3e-10 39.2 3.7 2.1 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 KUM66782.1 - 6.5e-09 35.6 4.4 6.5e-09 35.6 3.1 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 KUM66782.1 - 0.0002 21.5 3.7 0.038 14.2 0.3 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 KUM66782.1 - 0.00034 20.3 4.2 0.00034 20.3 2.9 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 KUM66782.1 - 0.002 18.4 1.9 0.002 18.4 1.3 2.7 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.2 KUM66782.1 - 0.0053 17.1 4.9 0.0053 17.1 3.4 2.5 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 KUM66782.1 - 0.012 15.3 0.6 0.012 15.3 0.4 2.2 3 0 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.1 KUM66782.1 - 5.2 7.7 7.9 0.92 10.1 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain NmrA PF05368.8 KUM66783.1 - 1.1e-14 54.3 0.0 1.5e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KUM66783.1 - 4.1e-05 23.6 0.0 6.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KUM66783.1 - 0.00044 19.9 0.0 0.0088 15.7 0.0 2.1 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KUM66783.1 - 0.002 18.0 0.0 0.0083 16.0 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 KUM66783.1 - 0.13 12.5 0.1 0.97 9.7 0.0 2.2 1 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain CHD5 PF04420.9 KUM66784.1 - 0.091 12.4 1.1 4.3 6.9 0.7 2.5 1 1 1 2 2 2 0 CHD5-like protein PepSY_TM_3 PF13706.1 KUM66784.1 - 0.23 10.9 3.0 1.3 8.4 0.4 2.9 2 0 0 2 2 2 0 PepSY-associated TM helix PhyH PF05721.8 KUM66785.1 - 0.0013 18.8 0.1 0.0034 17.4 0.1 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MFS_1 PF07690.11 KUM66786.1 - 2.2e-26 92.3 61.6 1.4e-22 79.9 13.3 3.3 2 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM66786.1 - 2.8e-09 36.0 11.6 2.8e-09 36.0 8.0 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter zf-LITAF-like PF10601.4 KUM66788.1 - 8.1e-05 22.4 1.1 0.00015 21.5 0.8 1.5 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain F-box-like PF12937.2 KUM66790.1 - 6.5e-06 25.7 0.0 1.8e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 F-box-like zf-CCCH PF00642.19 KUM66791.1 - 4e-05 23.1 0.9 4e-05 23.1 0.7 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Scaffolding_pro PF11418.3 KUM66791.1 - 0.083 13.2 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 Phi29 scaffolding protein IncA PF04156.9 KUM66791.1 - 0.37 10.3 3.5 0.58 9.7 2.5 1.2 1 0 0 1 1 1 0 IncA protein Glyco_hydro_76 PF03663.9 KUM66792.1 - 1.8e-47 162.5 12.4 3e-47 161.7 8.6 1.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 GST_N PF02798.15 KUM66794.1 - 1.5e-08 34.6 0.0 2.3e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KUM66794.1 - 3.8e-08 33.2 0.0 1e-07 31.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KUM66794.1 - 5.2e-07 29.8 0.0 8.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KUM66794.1 - 3.2e-05 23.8 0.0 5.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KUM66794.1 - 0.0028 17.5 0.0 0.0051 16.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain BetaGal_dom4_5 PF13364.1 KUM66795.1 - 4.6e-20 71.9 1.1 1.8e-18 66.8 1.1 2.8 2 1 0 2 2 2 1 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 KUM66795.1 - 3.4e-19 68.0 0.2 5.6e-19 67.3 0.1 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 BetaGal_dom2 PF10435.4 KUM66795.1 - 6.9e-19 67.8 0.0 1e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 KRAB PF01352.22 KUM66796.1 - 0.0027 17.1 0.6 0.0083 15.5 0.4 1.9 1 0 0 1 1 1 1 KRAB box RrnaAD PF00398.15 KUM66798.1 - 0.071 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PNPOx_C PF10590.4 KUM66801.1 - 1.8e-20 72.1 7.0 4.5e-20 70.8 3.5 2.5 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 KUM66801.1 - 2.6e-06 27.3 0.2 0.003 17.5 0.0 3.0 3 0 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase PPR_2 PF13041.1 KUM66802.1 - 1.1e-46 156.6 7.3 6.9e-10 38.7 0.0 13.0 10 4 5 15 15 15 10 PPR repeat family PPR_3 PF13812.1 KUM66802.1 - 2e-27 93.1 30.3 0.0017 18.4 0.0 15.7 16 0 0 16 16 16 7 Pentatricopeptide repeat domain PPR PF01535.15 KUM66802.1 - 1e-25 87.8 18.6 0.00042 20.0 0.0 13.3 14 2 0 14 14 14 6 PPR repeat PPR_1 PF12854.2 KUM66802.1 - 3.7e-21 74.3 2.0 1.3e-06 27.7 0.0 10.2 11 0 0 11 11 11 3 PPR repeat TPR_19 PF14559.1 KUM66802.1 - 1.7e-07 31.4 2.2 0.25 11.6 0.0 6.0 4 1 1 5 5 5 2 Tetratricopeptide repeat RPM2 PF08579.6 KUM66802.1 - 1.2e-05 25.4 0.0 0.0093 16.0 0.0 4.4 6 1 0 6 6 6 1 Mitochondrial ribonuclease P subunit (RPM2) Auts2 PF15336.1 KUM66802.1 - 0.012 15.6 2.7 0.055 13.4 0.4 2.3 2 0 0 2 2 2 0 Autism susceptibility gene 2 protein TPR_7 PF13176.1 KUM66802.1 - 0.19 11.6 3.8 1.5 8.8 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat FAD_binding_3 PF01494.14 KUM66803.1 - 7.2e-15 54.8 0.0 1.6e-14 53.7 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 KUM66803.1 - 8.4e-07 28.1 0.5 1.5e-06 27.3 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KUM66803.1 - 2.2e-06 27.5 0.2 5.5e-06 26.3 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KUM66803.1 - 2.8e-06 26.4 3.1 0.0004 19.3 0.7 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KUM66803.1 - 4.5e-05 22.7 1.8 4.6e-05 22.6 0.5 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KUM66803.1 - 0.0001 22.2 0.5 0.00017 21.5 0.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KUM66803.1 - 0.00046 20.5 1.6 0.0012 19.2 1.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KUM66803.1 - 0.0009 17.8 0.4 0.0013 17.2 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 KUM66803.1 - 0.0012 17.7 0.3 0.002 17.0 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KUM66803.1 - 0.0032 16.4 0.1 0.067 12.1 0.3 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 KUM66803.1 - 0.021 13.8 0.3 0.038 13.0 0.2 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 KUM66803.1 - 0.024 14.7 0.1 0.056 13.4 0.1 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KUM66803.1 - 0.056 13.0 0.3 0.1 12.1 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 KUM66803.1 - 0.067 11.8 0.0 0.11 11.1 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase 3HCDH_N PF02737.13 KUM66803.1 - 0.2 11.2 0.4 0.39 10.3 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_11 PF14833.1 KUM66805.1 - 1.4e-37 128.4 2.8 1.6e-28 99.2 0.0 2.3 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 KUM66805.1 - 7.2e-36 123.4 0.0 1.7e-35 122.2 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KUM66805.1 - 3.5e-05 24.1 0.1 0.00027 21.3 0.0 2.5 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 KUM66805.1 - 0.00012 21.7 0.0 0.0003 20.4 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KUM66805.1 - 0.009 15.1 0.0 0.022 13.9 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RGS PF00615.14 KUM66806.1 - 0.0006 19.8 0.0 0.0016 18.4 0.0 1.7 1 1 0 1 1 1 1 Regulator of G protein signaling domain Ank_2 PF12796.2 KUM66809.1 - 3.5e-55 184.3 0.5 2.6e-18 66.1 0.0 3.7 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 KUM66809.1 - 7.3e-43 142.2 0.9 1.7e-06 27.5 0.0 6.5 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 KUM66809.1 - 1e-29 102.3 0.3 6.2e-09 36.1 0.0 5.3 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM66809.1 - 1.9e-25 86.4 0.0 0.0017 18.4 0.0 6.6 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 KUM66809.1 - 2.7e-25 87.8 6.0 2.8e-07 30.5 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) UPF0547 PF10571.4 KUM66810.1 - 0.016 14.8 0.2 0.032 13.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 MFS_1 PF07690.11 KUM66811.1 - 2.1e-41 141.8 55.8 7.4e-34 116.9 25.5 3.5 1 1 2 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 KUM66811.1 - 4.3e-15 54.9 22.3 1.2e-14 53.4 15.5 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HCV_NS4a PF01006.15 KUM66811.1 - 3 7.4 6.7 1.7 8.2 2.7 2.1 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a Lactamase_B PF00753.22 KUM66812.1 - 4.3e-15 55.8 0.1 5.9e-15 55.4 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Glyco_hydro_cc PF11790.3 KUM66813.1 - 6.6e-12 45.3 0.0 7.7e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF500 PF04366.7 KUM66814.1 - 3.6e-38 129.8 0.3 5.9e-38 129.1 0.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) Acetyltransf_7 PF13508.1 KUM66815.1 - 1.9e-13 50.3 0.0 3.6e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KUM66815.1 - 3.9e-12 46.0 0.0 5.7e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KUM66815.1 - 5.2e-08 32.8 0.0 9.7e-08 31.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KUM66815.1 - 1.4e-07 31.6 0.0 1.7e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KUM66815.1 - 0.00068 19.5 0.0 0.0011 18.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KUM66815.1 - 0.0012 18.7 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 KUM66815.1 - 0.0013 18.9 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KUM66815.1 - 0.0036 17.2 0.0 0.0046 16.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KUM66815.1 - 0.025 14.3 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein F_bP_aldolase PF01116.15 KUM66817.1 - 1.9e-83 279.9 0.1 2.1e-83 279.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II PTE PF02126.13 KUM66817.1 - 0.071 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotriesterase family UNC-50 PF05216.8 KUM66818.1 - 0.018 14.2 2.8 0.037 13.2 1.9 1.5 1 0 0 1 1 1 0 UNC-50 family Beta-lactamase PF00144.19 KUM66819.1 - 9.7e-61 205.5 0.0 1.2e-60 205.3 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase TMEM154 PF15102.1 KUM66820.1 - 0.00018 21.2 0.4 0.00031 20.4 0.3 1.4 1 0 0 1 1 1 1 TMEM154 protein family Podoplanin PF05808.6 KUM66820.1 - 0.00027 20.5 4.3 0.00027 20.5 3.0 1.6 2 0 0 2 2 2 1 Podoplanin Syndecan PF01034.15 KUM66820.1 - 0.0014 18.2 0.7 0.0027 17.3 0.5 1.4 1 0 0 1 1 1 1 Syndecan domain Rifin_STEVOR PF02009.11 KUM66820.1 - 0.002 17.8 0.1 0.0028 17.3 0.1 1.2 1 0 0 1 1 1 1 Rifin/stevor family EphA2_TM PF14575.1 KUM66820.1 - 0.006 16.9 0.1 0.012 15.9 0.1 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.5 KUM66820.1 - 0.018 14.3 2.7 0.08 12.2 1.9 2.2 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TrbL PF04610.9 KUM66820.1 - 0.021 14.5 4.4 0.032 13.9 3.1 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein DUF1517 PF07466.6 KUM66820.1 - 0.022 13.7 6.7 0.032 13.2 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Glycophorin_A PF01102.13 KUM66820.1 - 0.022 14.4 12.1 0.087 12.5 7.4 2.0 1 1 1 2 2 2 0 Glycophorin A Herpes_gE PF02480.11 KUM66820.1 - 0.024 12.9 0.2 0.033 12.4 0.2 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Sporozoite_P67 PF05642.6 KUM66820.1 - 0.03 12.2 9.7 0.041 11.7 6.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2668 PF10873.3 KUM66820.1 - 0.033 14.3 1.1 0.075 13.1 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) Adeno_E3_CR2 PF02439.10 KUM66820.1 - 0.039 13.4 0.8 0.084 12.4 0.6 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Plasmodium_Vir PF05795.6 KUM66820.1 - 0.05 12.8 0.3 0.061 12.5 0.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4448 PF14610.1 KUM66820.1 - 0.058 12.8 0.1 0.12 11.8 0.0 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF4448) Sec10 PF07393.6 KUM66820.1 - 0.12 10.5 1.1 0.13 10.3 0.7 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 DAP10 PF07213.6 KUM66820.1 - 0.17 11.6 1.5 0.48 10.2 1.0 1.7 1 0 0 1 1 1 0 DAP10 membrane protein VSP PF03302.8 KUM66820.1 - 0.25 9.9 14.2 0.15 10.6 8.5 1.7 1 1 1 2 2 2 0 Giardia variant-specific surface protein Amnionless PF14828.1 KUM66820.1 - 0.34 9.3 1.5 0.65 8.4 1.0 1.5 1 1 0 1 1 1 0 Amnionless DUF515 PF04415.7 KUM66820.1 - 0.57 8.3 10.9 0.77 7.9 7.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Shisa PF13908.1 KUM66820.1 - 0.92 9.6 9.5 0.06 13.5 0.9 2.1 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Mid2 PF04478.7 KUM66820.1 - 1.1 8.6 10.1 1.6 8.1 5.9 1.9 1 1 1 2 2 2 0 Mid2 like cell wall stress sensor DUF1180 PF06679.7 KUM66820.1 - 1.1 9.1 11.6 2.9 7.7 8.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Med3 PF11593.3 KUM66820.1 - 1.3 8.1 12.0 1.8 7.7 8.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Macoilin PF09726.4 KUM66820.1 - 4 5.6 8.1 4.3 5.5 5.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Xan_ur_permease PF00860.15 KUM66822.1 - 3.6e-24 84.9 33.9 2.2e-23 82.4 22.0 2.5 2 1 0 2 2 2 1 Permease family BK_channel_a PF03493.13 KUM66822.1 - 0.25 11.2 0.8 4.3 7.3 0.1 2.7 3 0 0 3 3 3 0 Calcium-activated BK potassium channel alpha subunit MFS_1 PF07690.11 KUM66823.1 - 5.6e-38 130.5 45.3 5.6e-38 130.5 31.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM66823.1 - 1.3e-10 40.4 16.5 1.3e-10 40.4 11.5 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter DUF2422 PF10337.4 KUM66824.1 - 2.5e-111 372.6 4.0 2.5e-111 372.6 2.8 3.8 3 2 1 4 4 4 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 KUM66824.1 - 3.7e-15 55.9 15.8 3.7e-15 55.9 11.0 3.2 2 2 2 4 4 4 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 KUM66824.1 - 1.4e-13 50.9 0.0 6.5e-13 48.8 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2421) DUF939 PF06081.6 KUM66824.1 - 0.0022 17.8 8.9 0.0022 17.8 6.2 3.1 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF939) adh_short PF00106.20 KUM66825.1 - 5e-14 52.5 0.6 3.7e-13 49.7 0.3 2.2 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM66825.1 - 1.1e-09 38.4 0.7 1.3e-07 31.6 0.1 2.2 1 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM66825.1 - 2.6e-06 27.2 0.2 3.8e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KUM66825.1 - 0.0015 18.2 0.6 0.0036 17.0 0.2 1.8 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KUM66825.1 - 0.0043 16.5 0.1 0.0092 15.4 0.1 1.6 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Sugar_tr PF00083.19 KUM66826.1 - 8.3e-124 413.5 24.3 9.5e-124 413.3 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM66826.1 - 1.1e-25 90.1 35.7 7.7e-22 77.4 10.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ThiF PF00899.16 KUM66827.1 - 7e-43 145.7 0.0 1.2e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 KUM66827.1 - 2.6e-24 84.6 0.1 4.5e-24 83.8 0.1 1.4 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 KUM66827.1 - 8.9e-08 32.4 0.0 1.8e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 KUM66827.1 - 0.0007 19.6 0.0 0.0022 18.1 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 KUM66827.1 - 0.018 15.3 0.0 0.042 14.1 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF1469 PF07332.6 KUM66828.1 - 1.9 8.2 6.8 0.39 10.4 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Cation_ATPase_C PF00689.16 KUM66828.1 - 3.5 7.1 14.7 1.1 8.7 0.9 2.5 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus She9_MDM33 PF05546.6 KUM66829.1 - 3e-93 311.1 10.2 4.9e-93 310.4 7.1 1.3 1 0 0 1 1 1 1 She9 / Mdm33 family PsbH PF00737.15 KUM66829.1 - 0.0039 16.7 0.7 0.0075 15.8 0.5 1.4 1 0 0 1 1 1 1 Photosystem II 10 kDa phosphoprotein Hanta_nucleocap PF00846.13 KUM66829.1 - 0.099 11.3 0.3 0.16 10.6 0.2 1.4 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein DRY_EERY PF09750.4 KUM66829.1 - 0.93 9.5 7.3 1.6 8.8 3.0 2.3 2 0 0 2 2 2 0 Alternative splicing regulator UCR_TM PF02921.9 KUM66830.1 - 4.4e-19 68.4 0.5 8.7e-19 67.5 0.4 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 KUM66830.1 - 2.9e-16 58.8 0.1 5.9e-16 57.8 0.1 1.5 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain GST_N_3 PF13417.1 KUM66831.1 - 4.2e-18 65.3 0.0 7.3e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KUM66831.1 - 2.9e-15 55.9 0.0 5.7e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KUM66831.1 - 8.1e-12 45.1 0.0 1.7e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 KUM66831.1 - 1.2e-05 25.2 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.1 KUM66831.1 - 0.00014 21.7 0.1 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SH3_9 PF14604.1 KUM66832.1 - 1.2e-06 27.9 0.1 2.2e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KUM66832.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 SH3 domain RCR PF12273.3 KUM66832.1 - 0.2 12.2 2.1 0.33 11.5 0.9 1.9 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF2668 PF10873.3 KUM66832.1 - 2.6 8.2 9.3 0.24 11.5 2.7 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2668) SKG6 PF08693.5 KUM66832.1 - 3.3 7.0 6.4 0.16 11.3 0.4 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Vma12 PF11712.3 KUM66833.1 - 0.33 10.6 2.3 11 5.7 0.1 2.5 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Rieske PF00355.21 KUM66834.1 - 0.039 13.5 0.1 0.046 13.2 0.1 1.1 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain ATP-synt_ab PF00006.20 KUM66835.1 - 5.1e-62 209.1 0.0 8e-62 208.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KUM66835.1 - 3.4e-25 88.7 0.4 6.1e-25 87.8 0.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KUM66835.1 - 3.5e-24 84.8 2.4 2.4e-23 82.1 1.3 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain KaiC PF06745.8 KUM66835.1 - 0.0038 16.3 0.1 0.0067 15.5 0.1 1.4 1 0 0 1 1 1 1 KaiC Arch_ATPase PF01637.13 KUM66835.1 - 0.011 15.4 0.0 0.032 13.9 0.0 1.7 2 0 0 2 2 2 0 Archaeal ATPase AAA PF00004.24 KUM66835.1 - 0.012 15.7 0.0 0.96 9.6 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KUM66835.1 - 0.013 15.5 0.8 0.45 10.4 0.0 2.7 3 1 0 3 3 3 0 AAA ATPase domain AAA_25 PF13481.1 KUM66835.1 - 0.014 14.7 0.1 0.072 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KUM66835.1 - 0.019 14.6 0.2 1.1 8.9 0.0 3.0 3 1 1 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KUM66835.1 - 0.029 14.0 0.2 0.073 12.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.1 KUM66835.1 - 0.039 14.1 0.0 0.26 11.4 0.0 2.3 3 1 0 3 3 3 0 AAA domain DUF258 PF03193.11 KUM66835.1 - 0.063 12.4 0.1 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 KUM66835.1 - 0.081 11.7 0.7 0.28 9.9 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 KUM66835.1 - 0.093 12.9 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Alpha-amylase_C PF02806.13 KUM66836.1 - 2.1e-22 79.0 0.0 5.5e-22 77.7 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 KUM66836.1 - 4.3e-18 65.7 0.0 3.9e-14 52.7 0.1 2.6 2 1 1 3 3 3 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 KUM66836.1 - 1.8e-16 59.9 0.1 4.5e-16 58.6 0.1 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Cofilin_ADF PF00241.15 KUM66837.1 - 3e-26 91.7 1.0 3.4e-26 91.5 0.7 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SpoVR PF04293.8 KUM66837.1 - 0.098 11.0 0.1 0.12 10.7 0.1 1.1 1 0 0 1 1 1 0 SpoVR like protein COX4 PF02936.9 KUM66838.1 - 4.3e-49 165.9 0.2 5.4e-49 165.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV zf-MYND PF01753.13 KUM66839.1 - 6.3e-09 35.5 6.4 1e-08 34.8 4.4 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KUM66839.1 - 0.002 17.9 0.9 0.0041 16.9 0.6 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Fungal_lectin PF07938.7 KUM66840.1 - 1.3e-32 113.3 0.1 1.4e-32 113.2 0.0 1.0 1 0 0 1 1 1 1 Fungal fucose-specific lectin Aldo_ket_red PF00248.16 KUM66841.1 - 1.4e-20 73.2 0.0 1.6e-20 73.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AHH PF14412.1 KUM66841.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.3 1 1 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Aldo_ket_red PF00248.16 KUM66842.1 - 6.5e-30 103.9 0.0 8.1e-30 103.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0180 PF03698.8 KUM66843.1 - 0.12 12.1 0.2 0.29 10.9 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) Git3 PF11710.3 KUM66844.1 - 3.1e-33 115.0 14.2 7.3e-33 113.8 9.8 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 KUM66844.1 - 3.2e-12 46.0 0.6 8.4e-12 44.6 0.0 2.1 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 KUM66844.1 - 3.8e-07 29.4 10.7 7.1e-07 28.6 7.4 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 KUM66844.1 - 2.5e-05 23.3 15.6 3e-05 23.0 10.5 1.3 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor OapA_N PF08525.6 KUM66844.1 - 0.027 14.2 0.1 0.027 14.2 0.1 2.3 2 0 0 2 2 2 0 Opacity-associated protein A N-terminal motif Fungal_lectin PF07938.7 KUM66845.1 - 1.3e-31 110.0 0.5 1.5e-31 109.8 0.3 1.0 1 0 0 1 1 1 1 Fungal fucose-specific lectin DUF1144 PF06610.8 KUM66845.1 - 0.13 12.0 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1144) Amidohydro_2 PF04909.9 KUM66846.1 - 5.4e-26 91.7 0.0 6e-26 91.6 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase CBFD_NFYB_HMF PF00808.18 KUM66847.1 - 3.1e-15 55.9 0.4 3.1e-15 55.9 0.3 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Voltage_CLC PF00654.15 KUM66848.1 - 2.1e-89 300.0 29.9 2.1e-89 300.0 20.7 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KUM66848.1 - 1.4e-14 53.5 0.0 3.7e-06 26.6 0.0 2.4 2 0 0 2 2 2 2 CBS domain Pmp3 PF01679.12 KUM66849.1 - 1.2e-13 50.5 9.9 2.9e-12 46.1 1.8 2.1 2 0 0 2 2 2 2 Proteolipid membrane potential modulator ABC_tran PF00005.22 KUM66850.1 - 1.8e-37 128.7 0.0 1.8e-18 67.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KUM66850.1 - 1.2e-29 103.6 31.5 2.4e-21 76.3 10.5 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 KUM66850.1 - 1.1e-10 41.9 0.0 0.09 12.7 0.0 4.5 2 2 2 4 4 4 3 AAA domain AAA_29 PF13555.1 KUM66850.1 - 6.1e-06 25.6 0.5 0.075 12.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KUM66850.1 - 6.4e-06 26.6 0.5 0.039 14.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KUM66850.1 - 2.9e-05 23.4 3.7 0.36 10.0 0.0 4.3 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KUM66850.1 - 4.7e-05 23.5 0.3 0.8 9.8 0.1 3.5 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KUM66850.1 - 4.9e-05 24.1 0.0 0.22 12.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KUM66850.1 - 0.00012 21.3 0.3 0.33 10.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 KUM66850.1 - 0.00017 21.9 0.4 0.61 10.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 KUM66850.1 - 0.00018 21.4 0.0 0.39 10.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 KUM66850.1 - 0.00082 19.8 0.0 0.52 10.8 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_33 PF13671.1 KUM66850.1 - 0.0019 18.0 0.0 0.13 12.0 0.0 2.9 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.18 KUM66850.1 - 0.002 17.9 0.0 0.2 11.4 0.0 2.4 2 0 0 2 2 2 1 Dynamin family MobB PF03205.9 KUM66850.1 - 0.003 17.2 0.2 1 9.0 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Adeno_IVa2 PF02456.10 KUM66850.1 - 0.0046 15.6 0.1 0.026 13.1 0.0 1.9 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_16 PF13191.1 KUM66850.1 - 0.0047 16.9 0.3 3.7 7.5 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 KUM66850.1 - 0.013 14.4 0.0 0.82 8.5 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 KUM66850.1 - 0.054 12.9 0.1 6.1 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain DEAD PF00270.24 KUM66850.1 - 0.065 12.7 0.0 2.7 7.4 0.0 2.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF87 PF01935.12 KUM66850.1 - 0.087 12.6 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 GTP_EFTU PF00009.22 KUM66850.1 - 0.13 11.7 0.0 0.51 9.7 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 KUM66850.1 - 0.14 11.6 0.6 0.48 9.8 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family COX2-transmemb PF09125.5 KUM66850.1 - 0.2 11.2 1.3 0.68 9.5 0.4 2.3 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane GPI-anchored PF10342.4 KUM66851.1 - 1.1e-17 64.3 1.1 1.1e-17 64.3 0.7 3.5 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CBF PF03914.12 KUM66852.1 - 2e-48 163.9 0.2 4.6e-48 162.7 0.1 1.6 1 0 0 1 1 1 1 CBF/Mak21 family LemA PF04011.7 KUM66852.1 - 0.0079 15.3 1.6 0.011 14.8 0.2 1.9 2 0 0 2 2 2 1 LemA family MFS_1 PF07690.11 KUM66853.1 - 2.6e-26 92.1 45.3 4.2e-15 55.3 13.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KUM66853.1 - 0.00011 20.6 4.5 0.00017 19.9 3.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UCR_Fe-S_N PF10399.4 KUM66853.1 - 0.17 11.0 5.1 8.2 5.6 0.0 3.0 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal NAD_binding_10 PF13460.1 KUM66854.1 - 0.011 15.7 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 KUM66854.1 - 0.03 13.0 0.0 0.19 10.4 0.0 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Sugar_tr PF00083.19 KUM66855.1 - 5.5e-71 239.4 23.7 6.6e-71 239.2 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM66855.1 - 2.5e-18 65.9 40.6 3.2e-14 52.3 22.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NfeD PF01957.13 KUM66855.1 - 0.037 14.1 0.2 0.037 14.1 0.2 3.4 2 2 0 3 3 3 0 NfeD-like C-terminal, partner-binding Mt_ATP-synt_B PF05405.9 KUM66856.1 - 3.2e-18 65.7 0.0 4.8e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Sel1 PF08238.7 KUM66857.1 - 2.4e-21 75.6 6.5 3.8e-07 30.5 0.1 3.6 3 0 0 3 3 3 3 Sel1 repeat TPR_16 PF13432.1 KUM66857.1 - 0.07 13.8 2.9 1.9 9.2 1.0 3.0 1 1 2 3 3 3 0 Tetratricopeptide repeat zf-LITAF-like PF10601.4 KUM66858.1 - 0.0051 16.6 0.3 0.0071 16.1 0.2 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Cys_rich_CPXG PF14255.1 KUM66858.1 - 0.12 12.2 0.4 0.19 11.5 0.3 1.3 1 0 0 1 1 1 0 Cysteine-rich CPXCG ATP_transf PF09830.4 KUM66859.1 - 1.3e-19 69.6 0.5 2.4e-19 68.8 0.0 1.7 2 0 0 2 2 2 1 ATP adenylyltransferase PsbK PF02533.10 KUM66859.1 - 0.11 12.4 0.5 0.43 10.5 0.2 2.0 2 0 0 2 2 2 0 Photosystem II 4 kDa reaction centre component zf-C2H2_4 PF13894.1 KUM66860.1 - 0.00019 21.5 15.6 0.097 13.0 0.0 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KUM66860.1 - 0.00078 19.6 20.4 0.81 10.1 0.1 4.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KUM66860.1 - 0.0099 15.7 0.8 0.18 11.7 0.6 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger IBR PF01485.16 KUM66860.1 - 6.3 6.7 9.0 1e+03 -0.4 6.2 2.9 1 1 0 1 1 1 0 IBR domain PAF-AH_p_II PF03403.8 KUM66861.1 - 4.6e-15 54.8 0.0 5.2e-07 28.2 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KUM66861.1 - 2.5e-13 49.9 0.5 3.7e-13 49.4 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KUM66861.1 - 8.6e-09 35.6 0.4 1.3e-08 34.9 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KUM66861.1 - 9.6e-06 24.6 0.0 1.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.3 KUM66861.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Fungal_trans_2 PF11951.3 KUM66862.1 - 1.5e-13 50.1 2.7 4.6e-13 48.5 1.9 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM66862.1 - 1.9e-06 27.6 6.5 3.4e-06 26.8 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tub_2 PF04525.7 KUM66863.1 - 1.6e-25 89.5 0.0 1.9e-25 89.3 0.0 1.0 1 0 0 1 1 1 1 Tubby C 2 Kdo PF06293.9 KUM66864.1 - 0.00016 20.8 0.0 0.00018 20.6 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KUM66864.1 - 0.00078 18.6 0.0 0.00082 18.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain FAD_binding_3 PF01494.14 KUM66865.1 - 2e-21 76.4 0.1 4.8e-21 75.2 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KUM66865.1 - 0.0079 15.1 0.2 2.1 7.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Cbl_N2 PF02761.9 KUM66865.1 - 0.12 12.4 0.1 0.42 10.7 0.0 1.9 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, EF hand-like domain Alpha-amylase PF00128.19 KUM66866.1 - 6.8e-66 222.8 0.6 6.8e-65 219.5 0.4 2.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 KUM66866.1 - 0.0056 16.7 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Tmemb_14 PF03647.8 KUM66867.1 - 1.7e-24 86.0 2.9 1.9e-24 85.8 2.0 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF543 PF04418.7 KUM66867.1 - 0.29 11.1 2.9 0.23 11.4 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF543) DUF3176 PF11374.3 KUM66868.1 - 2.3e-37 127.2 1.7 4.5e-37 126.3 1.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF3366 PF11846.3 KUM66869.1 - 0.39 10.5 5.4 1.1 9.1 0.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3366) DUF1049 PF06305.6 KUM66869.1 - 0.57 9.7 7.3 0.2 11.1 1.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1049) MFS_1 PF07690.11 KUM66869.1 - 0.77 8.4 17.4 0.77 8.4 6.8 2.5 1 1 1 2 2 2 0 Major Facilitator Superfamily DUF202 PF02656.10 KUM66869.1 - 1.3 9.2 5.0 2 8.6 0.5 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF202) TspO_MBR PF03073.10 KUM66869.1 - 1.8 8.0 14.1 0.078 12.4 3.1 2.6 2 1 0 3 3 3 0 TspO/MBR family PAP2 PF01569.16 KUM66869.1 - 8.8 6.0 11.8 7 6.3 0.3 2.6 2 1 0 2 2 2 0 PAP2 superfamily TRI5 PF06330.6 KUM66870.1 - 8.6e-142 472.2 0.4 1e-141 471.9 0.3 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) SPC25 PF06703.6 KUM66871.1 - 1e-45 155.1 0.0 1.2e-45 155.0 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Synaptobrevin PF00957.16 KUM66872.1 - 8.5 6.0 6.3 49 3.6 3.1 2.3 2 0 0 2 2 2 0 Synaptobrevin Cys_Met_Meta_PP PF01053.15 KUM66873.1 - 1.2e-06 27.0 0.0 1.3e-06 26.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF4129 PF13559.1 KUM66873.1 - 0.007 16.3 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) MMS19_C PF12460.3 KUM66874.1 - 8.2e-126 420.0 7.2 8.2e-126 420.0 5.0 3.2 2 1 1 3 3 3 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.1 KUM66874.1 - 6.8e-95 317.2 0.0 1.8e-93 312.6 0.0 2.8 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.1 KUM66874.1 - 1.1e-07 31.9 13.1 0.024 14.8 0.5 6.6 7 1 0 7 7 7 3 HEAT repeats HEAT PF02985.17 KUM66874.1 - 0.0037 17.2 13.6 28 5.1 0.2 7.5 7 0 0 7 7 7 0 HEAT repeat DUF2435 PF10363.4 KUM66874.1 - 0.0056 16.5 1.8 3.7 7.5 0.0 4.3 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) Arm PF00514.18 KUM66874.1 - 0.041 13.7 4.6 1.5 8.7 0.0 4.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 KUM66874.1 - 1.6 9.3 21.9 14 6.3 2.4 6.4 6 1 0 6 6 6 0 HEAT-like repeat Fasciclin PF02469.17 KUM66875.1 - 4.7e-07 29.8 0.0 8.3e-07 29.0 0.0 1.4 1 1 0 1 1 1 1 Fasciclin domain DUF106 PF01956.11 KUM66876.1 - 4.3e-55 185.7 1.6 5.6e-55 185.4 1.1 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 ADIP PF11559.3 KUM66878.1 - 0.0047 16.8 16.0 0.0047 16.8 11.1 3.2 1 1 2 3 3 3 1 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 KUM66878.1 - 0.63 9.1 6.6 1.2 8.3 1.5 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Vac_Fusion PF02346.11 KUM66878.1 - 0.65 9.4 0.1 0.65 9.4 0.0 3.8 4 0 0 4 4 4 0 Chordopoxvirus fusion protein APG6 PF04111.7 KUM66878.1 - 1.1 8.2 39.0 0.6 9.1 17.3 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF1319 PF07028.6 KUM66878.1 - 1.2 9.3 16.9 1.7 8.8 1.6 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1319) DXP_reductoisom PF02670.11 KUM66878.1 - 4 7.9 8.5 1.1 9.8 0.5 2.8 2 1 1 3 3 3 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase CAF-1_p150 PF11600.3 KUM66878.1 - 7.6 5.8 29.5 0.21 10.9 15.0 1.9 1 1 1 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ank_2 PF12796.2 KUM66880.1 - 6.4e-59 196.2 30.2 1.6e-18 66.7 1.3 5.1 3 1 4 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KUM66880.1 - 1e-43 146.9 10.3 3.4e-11 43.3 0.0 7.6 3 1 5 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.25 KUM66880.1 - 5.6e-39 130.0 29.1 2.4e-06 27.0 0.3 9.8 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.1 KUM66880.1 - 2e-26 91.4 26.5 1.5e-05 25.0 0.3 8.5 2 1 6 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM66880.1 - 2.9e-23 79.6 10.5 0.0034 17.4 0.0 9.5 10 0 0 10 10 10 5 Ankyrin repeat NACHT PF05729.7 KUM66880.1 - 2.6e-10 40.2 0.1 5.7e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KUM66880.1 - 1.7e-08 34.6 0.0 1.7e-08 34.6 0.0 3.5 4 1 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 KUM66880.1 - 2e-06 27.9 0.1 5.9e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KUM66880.1 - 0.074 11.9 0.1 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AA_permease_2 PF13520.1 KUM66883.1 - 1.5e-37 129.1 50.9 1.9e-37 128.8 35.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KUM66883.1 - 8.5e-27 93.6 47.0 1.1e-26 93.2 32.5 1.0 1 0 0 1 1 1 1 Amino acid permease DELLA PF12041.3 KUM66884.1 - 0.093 12.4 0.2 0.19 11.4 0.1 1.6 1 1 1 2 2 2 0 Transcriptional regulator DELLA protein N terminal FAD_binding_4 PF01565.18 KUM66885.1 - 1.1e-09 37.9 3.9 2.2e-09 36.9 2.7 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KUM66885.1 - 3.5e-09 36.4 0.0 6.5e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KUM66885.1 - 0.14 11.2 0.7 0.35 9.9 0.2 1.7 2 0 0 2 2 2 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding DUF3445 PF11927.3 KUM66886.1 - 5.3e-77 258.5 0.1 6.3e-77 258.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) TPR_11 PF13414.1 KUM66887.1 - 3.1e-25 87.6 4.9 2e-11 43.3 0.4 4.4 3 1 1 4 4 4 4 TPR repeat TPR_1 PF00515.23 KUM66887.1 - 2.8e-22 77.3 3.0 2.2e-08 33.3 0.0 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 KUM66887.1 - 3e-22 76.6 3.0 1.4e-07 30.8 0.1 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 KUM66887.1 - 3.3e-17 61.4 5.5 7.3e-05 23.0 0.0 6.1 5 1 2 7 7 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 KUM66887.1 - 1.3e-16 60.7 5.8 2.2e-06 28.1 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 KUM66887.1 - 5.2e-15 54.3 3.7 0.0011 19.0 0.1 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 KUM66887.1 - 7.1e-14 51.8 2.8 0.00052 20.2 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KUM66887.1 - 2.8e-12 46.3 6.3 5.7e-08 32.5 0.5 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 KUM66887.1 - 5.9e-11 41.3 1.5 0.00093 18.8 0.0 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 KUM66887.1 - 1.3e-10 40.2 0.4 0.00035 20.1 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 KUM66887.1 - 1.9e-10 40.7 3.7 0.0033 17.5 0.0 4.7 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 KUM66887.1 - 1.5e-07 31.1 4.2 0.0027 17.5 0.0 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KUM66887.1 - 1.1e-06 28.6 1.6 4.2e-05 23.5 0.4 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KUM66887.1 - 5.3e-05 23.4 2.3 0.86 10.2 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_3 PF07720.7 KUM66887.1 - 0.00014 21.5 0.0 0.085 12.6 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.1 KUM66887.1 - 0.00022 20.3 0.3 0.3 10.0 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 KUM66887.1 - 0.0072 16.2 2.0 0.44 10.5 0.4 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 KUM66887.1 - 0.022 14.6 1.9 1.3 8.9 0.5 3.8 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain TOM20_plant PF06552.7 KUM66887.1 - 0.059 12.9 0.2 2.7 7.5 0.0 3.0 3 1 1 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 DED PF01335.16 KUM66887.1 - 0.2 11.8 0.2 21 5.2 0.0 2.4 2 0 0 2 2 2 0 Death effector domain DUF4192 PF13830.1 KUM66887.1 - 1.1 8.8 7.6 2.3 7.7 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4192) Amidase PF01425.16 KUM66888.1 - 9.2e-88 295.0 0.0 1.2e-87 294.6 0.0 1.1 1 0 0 1 1 1 1 Amidase Ribonuc_L-PSP PF01042.16 KUM66889.1 - 1.8e-19 69.6 0.0 2.2e-19 69.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Aldedh PF00171.17 KUM66890.1 - 6.7e-158 525.8 0.1 8.1e-158 525.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family 2-Hacid_dh_C PF02826.14 KUM66892.1 - 2.5e-40 137.5 0.3 3.5e-40 137.0 0.2 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KUM66892.1 - 2.1e-10 40.2 0.0 2.6e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Gp_dh_N PF00044.19 KUM66892.1 - 0.045 13.7 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KUM66892.1 - 0.098 13.1 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CDP-OH_P_transf PF01066.16 KUM66894.1 - 1.9e-16 60.2 2.8 1.9e-16 60.2 2.0 3.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF3659 PF12396.3 KUM66895.1 - 1.9e-19 69.0 1.1 4.4e-19 67.9 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3659) RPW8 PF05659.6 KUM66895.1 - 0.0027 17.2 1.0 0.0057 16.2 0.7 1.6 1 1 0 1 1 1 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 Pex19 PF04614.7 KUM66895.1 - 0.037 13.6 3.4 0.03 13.9 0.9 1.8 1 1 1 2 2 2 0 Pex19 protein family LIN37 PF15306.1 KUM66895.1 - 0.048 13.6 0.5 0.077 12.9 0.3 1.3 1 0 0 1 1 1 0 LIN37 THDPS_N_2 PF14805.1 KUM66895.1 - 0.096 12.5 0.3 1.3 8.9 0.0 2.7 3 0 0 3 3 3 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal CorA PF01544.13 KUM66895.1 - 0.13 11.3 0.1 0.17 10.8 0.1 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein GCIP PF13324.1 KUM66895.1 - 0.19 10.9 2.9 1.6 7.9 0.8 2.1 1 1 1 2 2 2 0 Grap2 and cyclin-D-interacting DUF3659 PF12396.3 KUM66896.1 - 2.6e-131 427.4 55.6 5.4e-23 80.4 2.0 8.0 8 0 0 8 8 8 7 Protein of unknown function (DUF3659) Apolipoprotein PF01442.13 KUM66896.1 - 6.1e-06 25.8 2.3 7e-05 22.4 0.7 2.6 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 KUM66896.1 - 0.0053 17.1 25.6 0.052 13.9 5.9 4.5 2 1 2 4 4 4 2 Bacterial protein of unknown function (DUF883) Prominin PF05478.6 KUM66896.1 - 0.067 10.7 1.7 0.053 11.0 0.2 1.5 2 0 0 2 2 2 0 Prominin AAA_13 PF13166.1 KUM66896.1 - 0.15 10.4 2.2 0.23 9.9 1.5 1.2 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.7 KUM66896.1 - 0.19 11.4 9.9 2.5 7.8 0.2 3.1 2 1 1 3 3 3 0 Laminin Domain II YtxH PF12732.2 KUM66896.1 - 3.7 7.9 31.5 99 3.4 0.0 5.4 3 1 0 3 3 3 0 YtxH-like protein DUF2959 PF11172.3 KUM66896.1 - 3.9 7.1 19.4 0.76 9.5 3.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2959) DUF3584 PF12128.3 KUM66896.1 - 8.9 3.4 10.4 13 2.9 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NTR2 PF15458.1 KUM66898.1 - 1.9e-72 243.5 15.1 2.5e-72 243.1 10.5 1.1 1 0 0 1 1 1 1 Nineteen complex-related protein 2 LSM PF01423.17 KUM66899.1 - 6.2e-16 57.7 0.2 8.1e-16 57.3 0.2 1.1 1 0 0 1 1 1 1 LSM domain Peptidase_M1 PF01433.15 KUM66900.1 - 5.6e-06 25.6 0.0 0.62 9.0 0.0 3.2 3 0 0 3 3 3 3 Peptidase family M1 Herpes_TAF50 PF03326.8 KUM66903.1 - 2.8 6.7 10.1 3.5 6.4 7.0 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Lactonase PF10282.4 KUM66904.1 - 4.2e-76 256.2 0.0 5.5e-76 255.8 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller GMC_oxred_N PF00732.14 KUM66905.1 - 2.2e-83 279.8 0.1 4.4e-83 278.8 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KUM66905.1 - 2.4e-28 99.2 0.0 4.4e-28 98.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KUM66905.1 - 0.00045 19.2 0.0 0.00077 18.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KUM66905.1 - 0.00072 19.5 0.0 0.0028 17.6 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KUM66905.1 - 0.0021 16.9 0.0 0.011 14.5 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KUM66905.1 - 0.0044 15.9 0.0 0.0067 15.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KUM66905.1 - 0.014 15.3 0.1 0.69 9.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KUM66905.1 - 0.063 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pox_polyA_pol PF03296.8 KUM66905.1 - 0.09 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase nucleotidyltransferase domain FtsX PF02687.16 KUM66906.1 - 0.17 11.6 2.6 3.3 7.5 0.6 2.1 2 0 0 2 2 2 0 FtsX-like permease family 2OG-FeII_Oxy PF03171.15 KUM66907.1 - 5.6e-23 81.1 0.0 1.3e-22 79.9 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KUM66907.1 - 9.1e-15 55.2 0.0 1.4e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Carbpep_Y_N PF05388.6 KUM66907.1 - 0.085 13.0 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide Terpene_synth_C PF03936.11 KUM66908.1 - 2.6e-05 23.6 0.0 3.3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DUF1814 PF08843.6 KUM66909.1 - 3.7e-06 26.8 0.1 4.6e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) DUF2204 PF09970.4 KUM66909.1 - 0.016 14.6 0.0 0.036 13.5 0.0 1.7 1 1 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) Pyr_redox_2 PF07992.9 KUM66912.1 - 2.2e-17 63.6 0.0 3e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KUM66912.1 - 5.9e-09 35.2 0.4 0.0012 17.7 0.0 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KUM66912.1 - 9.4e-07 29.0 0.1 0.006 16.6 0.0 3.0 1 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KUM66912.1 - 2.3e-06 26.3 0.0 0.00014 20.4 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 KUM66912.1 - 0.00015 20.7 0.4 0.0061 15.4 0.0 2.8 2 1 1 3 3 3 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KUM66912.1 - 0.00028 20.7 0.2 0.75 9.5 0.0 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KUM66912.1 - 0.00058 18.8 0.2 0.0019 17.1 0.0 1.9 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.7 KUM66912.1 - 0.00098 18.1 0.1 0.13 11.1 0.0 2.2 1 1 1 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KUM66912.1 - 0.0015 18.5 0.1 0.0042 17.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KUM66912.1 - 0.0018 17.3 0.0 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 KUM66912.1 - 0.0078 15.3 0.1 0.014 14.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain K_oxygenase PF13434.1 KUM66912.1 - 0.026 13.4 0.0 5.5 5.8 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 KUM66912.1 - 0.043 12.8 0.5 0.098 11.7 0.1 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 KUM66912.1 - 0.16 12.4 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RRM_1 PF00076.17 KUM66913.1 - 5.5e-37 125.2 0.1 3.8e-20 71.3 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KUM66913.1 - 3.9e-28 97.2 0.1 1.1e-17 63.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KUM66913.1 - 2.6e-12 46.3 0.0 1.5e-09 37.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.13 KUM66913.1 - 4.4e-12 45.4 0.0 1.1e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM66913.1 - 8.6e-07 28.7 12.9 1.5e-06 28.0 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 KUM66914.1 - 7.8e-66 222.4 0.0 1e-65 222.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Piwi PF02171.12 KUM66915.1 - 5.5e-73 245.5 0.0 9.3e-73 244.8 0.0 1.4 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KUM66915.1 - 2.6e-12 46.1 0.0 8.3e-12 44.5 0.0 1.8 2 0 0 2 2 2 1 PAZ domain DUF1785 PF08699.5 KUM66915.1 - 9e-12 44.1 0.2 2.4e-11 42.7 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) SHS2_Rpb7-N PF03876.12 KUM66917.1 - 7.6e-14 51.5 0.0 1.4e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 KUM66917.1 - 3.4e-09 36.6 0.0 5.2e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain DUF962 PF06127.6 KUM66918.1 - 2.7e-25 88.0 2.1 3.7e-25 87.6 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) ATP-synt_ab PF00006.20 KUM66919.1 - 2.8e-70 236.1 0.0 3.9e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KUM66919.1 - 1.6e-25 89.7 0.4 4.3e-25 88.3 0.0 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KUM66919.1 - 1.1e-15 57.5 2.7 2.7e-15 56.3 1.9 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KUM66919.1 - 0.0071 16.2 1.0 0.03 14.2 0.7 2.0 1 1 1 2 2 2 1 HAS barrel domain Ald_Xan_dh_C PF01315.17 KUM66919.1 - 0.08 13.0 0.5 0.18 11.8 0.4 1.6 1 0 0 1 1 1 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain THF_DHG_CYH PF00763.18 KUM66920.1 - 1.5e-19 70.1 0.1 2.3e-19 69.5 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 KUM66920.1 - 8.3e-12 44.4 0.1 8.4e-10 37.9 0.0 2.9 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF3143 PF11341.3 KUM66920.1 - 0.075 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3143) Peroxin-13_N PF04088.8 KUM66921.1 - 6.9e-58 195.0 0.0 1.1e-57 194.4 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 KUM66921.1 - 1.8e-09 36.9 0.0 3.4e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KUM66921.1 - 4.3e-08 32.4 0.0 7.7e-08 31.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KUM66921.1 - 3.8e-06 26.3 0.1 6.1e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain OAD_gamma PF04277.8 KUM66921.1 - 0.077 13.3 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Pex2_Pex12 PF04757.9 KUM66921.1 - 0.17 11.2 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region GSK-3_bind PF05350.7 KUM66923.1 - 0.015 14.7 3.1 0.53 9.6 3.0 2.5 3 0 0 3 3 3 0 Glycogen synthase kinase-3 binding ERO1 PF04137.10 KUM66924.1 - 3.2e-136 454.0 0.0 3.9e-136 453.7 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) PALP PF00291.20 KUM66925.1 - 6.6e-46 156.9 0.3 3.4e-45 154.5 0.2 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_28 PF02636.12 KUM66926.1 - 5.1e-37 127.6 0.0 7.4e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase APG6 PF04111.7 KUM66927.1 - 1.4e-123 412.0 0.0 1.7e-123 411.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 CCDC155 PF14662.1 KUM66927.1 - 0.042 13.4 3.1 0.072 12.6 2.1 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 CENP-F_leu_zip PF10473.4 KUM66927.1 - 0.16 11.7 2.3 0.32 10.8 1.6 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MbeD_MobD PF04899.7 KUM66927.1 - 1.2 9.1 3.9 1.7 8.6 0.7 2.3 1 1 1 2 2 2 0 MbeD/MobD like Scm3 PF10384.4 KUM66928.1 - 9.7e-23 79.4 0.0 3.5e-22 77.6 0.0 2.0 2 0 0 2 2 2 1 Centromere protein Scm3 Myb_DNA-binding PF00249.26 KUM66928.1 - 0.027 14.5 0.2 6.9 6.8 0.0 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain Abhydrolase_6 PF12697.2 KUM66929.1 - 9.3e-17 61.6 1.0 1.1e-16 61.4 0.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM66929.1 - 4.9e-08 32.8 0.0 7.5e-08 32.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KUM66930.1 - 6.6e-24 85.0 3.4 8e-24 84.7 2.3 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KUM66930.1 - 9.4e-08 31.9 0.1 1.5e-07 31.3 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KUM66930.1 - 0.011 15.0 0.2 0.017 14.4 0.1 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 KUM66930.1 - 0.03 13.8 0.7 0.26 10.7 0.5 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Lipase_2 PF01674.13 KUM66930.1 - 0.046 13.0 0.1 0.065 12.5 0.1 1.2 1 0 0 1 1 1 0 Lipase (class 2) PGAP1 PF07819.8 KUM66930.1 - 0.058 12.9 0.6 0.081 12.4 0.4 1.2 1 0 0 1 1 1 0 PGAP1-like protein Fungal_trans PF04082.13 KUM66931.1 - 3.8e-19 68.5 1.9 5.9e-19 67.9 1.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 KUM66931.1 - 4.2e-07 29.9 15.2 9.5e-05 22.4 4.0 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KUM66931.1 - 5.1e-05 23.3 13.3 0.0038 17.4 3.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KUM66931.1 - 0.00018 21.6 14.4 0.032 14.5 4.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KUM66931.1 - 0.54 10.2 4.2 14 5.7 0.1 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger UPRTase PF14681.1 KUM66932.1 - 3.2e-74 248.6 0.0 3.7e-74 248.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KUM66932.1 - 1.7e-06 27.7 0.1 5.2e-06 26.1 0.1 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Rhabdo_glycop PF00974.13 KUM66933.1 - 0.0024 16.1 0.0 0.0028 15.9 0.0 1.1 1 0 0 1 1 1 1 Rhabdovirus spike glycoprotein Sin_N PF04801.8 KUM66934.1 - 1.3e-25 90.1 2.8 9.1e-25 87.3 2.0 1.8 1 1 0 1 1 1 1 Sin-like protein conserved region NIR_SIR PF01077.17 KUM66935.1 - 1.6e-49 167.2 0.0 4.4e-42 143.1 0.0 2.8 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 KUM66935.1 - 9.8e-28 95.5 0.0 3.3e-13 49.0 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 KUM66935.1 - 2.9e-26 92.1 0.0 5.9e-26 91.1 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 KUM66935.1 - 4.3e-08 32.9 0.1 9.2e-08 31.8 0.1 1.5 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg AAA_31 PF13614.1 KUM66935.1 - 0.11 12.4 0.0 0.56 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Abhydrolase_3 PF07859.8 KUM66936.1 - 2.3e-28 99.2 0.0 3e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KUM66936.1 - 1.1e-12 47.3 0.0 2.7e-12 46.0 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 KUM66936.1 - 0.0033 16.6 0.0 0.011 14.9 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KUM66936.1 - 0.018 14.7 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family MmgE_PrpD PF03972.9 KUM66937.1 - 2e-98 329.4 1.4 2.5e-98 329.1 1.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family FokI_C PF02980.11 KUM66937.1 - 0.041 13.5 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease FokI, catalytic domain AAA_29 PF13555.1 KUM66937.1 - 0.21 11.1 1.4 0.93 9.0 0.2 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Kei1 PF08552.6 KUM66938.1 - 2.1e-60 203.6 2.5 2.9e-60 203.1 1.7 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 ATP-synt_C PF00137.16 KUM66939.1 - 3.2e-27 94.2 26.4 6.9e-17 61.1 4.9 2.4 3 0 0 3 3 3 2 ATP synthase subunit C Lysis_S PF04971.7 KUM66939.1 - 0.14 11.8 1.0 0.43 10.3 0.0 2.2 2 0 0 2 2 2 0 Lysis protein S Oxidored_q2 PF00420.19 KUM66939.1 - 0.47 10.0 5.9 0.37 10.4 1.3 2.7 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Ras PF00071.17 KUM66940.1 - 2.4e-59 199.3 0.2 3.1e-59 198.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KUM66940.1 - 7.7e-21 74.8 0.0 1.2e-20 74.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KUM66940.1 - 1.3e-17 63.5 0.1 1.6e-17 63.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KUM66940.1 - 2.3e-07 30.4 0.0 1.1e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KUM66940.1 - 4e-06 26.1 0.1 4.9e-06 25.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KUM66940.1 - 4.7e-06 25.9 0.0 9.6e-06 24.9 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KUM66940.1 - 1e-05 25.4 0.0 1.5e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KUM66940.1 - 0.025 14.4 0.1 2.9 7.6 0.0 2.5 2 1 0 2 2 2 0 Dynamin family DUF258 PF03193.11 KUM66940.1 - 0.043 13.0 0.2 0.88 8.7 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 KUM66940.1 - 0.049 13.5 0.2 0.098 12.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KUM66940.1 - 0.12 12.5 0.0 1.1 9.4 0.0 2.4 1 1 0 1 1 1 0 AAA domain RNA_pol PF00940.14 KUM66941.1 - 1e-167 557.7 0.0 1.4e-167 557.2 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 KUM66941.1 - 7.1e-76 255.4 0.9 1.1e-75 254.8 0.6 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Fungal_trans PF04082.13 KUM66942.1 - 2.1e-37 128.4 0.0 4.5e-37 127.3 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM66942.1 - 2.1e-09 37.1 9.0 3.5e-09 36.4 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KUM66942.1 - 0.007 14.9 0.1 0.021 13.4 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Methyltransf_23 PF13489.1 KUM66943.1 - 6.8e-22 77.9 0.0 1.6e-21 76.6 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KUM66943.1 - 1.1e-11 44.5 0.0 5.8e-11 42.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KUM66943.1 - 1.7e-10 41.4 0.0 9e-10 39.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KUM66943.1 - 1.4e-09 38.2 0.0 7.1e-09 36.0 0.0 2.2 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KUM66943.1 - 5.4e-08 33.2 0.0 1.6e-07 31.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 KUM66943.1 - 0.00025 20.1 0.0 0.0024 16.9 0.0 2.4 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_25 PF13649.1 KUM66943.1 - 0.001 19.3 0.0 0.0034 17.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KUM66943.1 - 0.0024 17.8 0.0 0.0097 15.9 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 KUM66943.1 - 0.0081 16.1 0.0 0.02 14.9 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 KUM66943.1 - 0.011 14.8 0.0 0.27 10.3 0.0 2.2 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KUM66943.1 - 0.051 12.6 0.0 0.13 11.3 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.9 KUM66943.1 - 0.15 11.4 0.0 1.8 7.9 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Zn_clus PF00172.13 KUM66944.1 - 6.7e-09 35.5 6.4 1.1e-08 34.8 4.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med1 PF10744.4 KUM66944.1 - 0.05 12.3 0.2 0.067 11.9 0.1 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription subunit 1 SSP160 PF06933.6 KUM66944.1 - 4.6 5.0 13.7 8.1 4.2 9.5 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Melibiase PF02065.13 KUM66945.1 - 4.3e-12 45.4 0.7 7.2e-12 44.6 0.5 1.3 1 0 0 1 1 1 1 Melibiase Ricin_B_lectin PF00652.17 KUM66945.1 - 0.08 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain PhyH PF05721.8 KUM66946.1 - 9.1e-10 38.9 0.2 2.5e-09 37.4 0.2 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF2036 PF09724.4 KUM66947.1 - 2.2e-11 43.4 0.0 7.6e-11 41.7 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) DUF3933 PF13069.1 KUM66947.1 - 0.097 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3933) Acetyltransf_7 PF13508.1 KUM66948.1 - 4.7e-07 29.8 0.0 1.2e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KUM66948.1 - 1.7e-05 24.7 0.0 9e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KUM66948.1 - 9.6e-05 22.2 0.1 0.00044 20.0 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KUM66948.1 - 0.0019 18.3 0.1 0.0086 16.1 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KUM66948.1 - 0.01 15.5 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_3 PF13302.1 KUM66948.1 - 0.02 15.0 0.2 0.075 13.2 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain HORMA PF02301.13 KUM66949.1 - 6.8e-27 94.3 0.0 8.8e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 HORMA domain IBN_N PF03810.14 KUM66950.1 - 5.1e-08 32.7 0.2 5.1e-08 32.7 0.1 3.2 3 1 1 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KUM66950.1 - 2e-05 24.5 0.4 0.018 14.9 0.0 4.5 4 1 0 4 4 4 1 Exportin 1-like protein CAS_CSE1 PF03378.10 KUM66950.1 - 0.00018 19.9 0.0 0.0004 18.7 0.0 1.6 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cnd3 PF12719.2 KUM66950.1 - 0.003 16.6 0.3 0.018 14.0 0.1 2.4 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Proteasom_PSMB PF10508.4 KUM66950.1 - 0.016 13.4 0.3 2 6.5 0.0 2.9 3 1 1 4 4 4 0 Proteasome non-ATPase 26S subunit Gmad2 PF10648.4 KUM66950.1 - 0.066 13.3 0.0 0.29 11.3 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin-like domain of bacterial spore germination Het-C PF07217.6 KUM66951.1 - 6.6e-277 919.6 0.4 6.6e-277 919.6 0.3 2.3 2 1 0 2 2 2 1 Heterokaryon incompatibility protein Het-C Peptidase_C48 PF02902.14 KUM66953.1 - 6.1e-28 97.9 0.0 1e-27 97.2 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain zf-HIT PF04438.11 KUM66955.1 - 1.3e-10 40.7 10.2 2.6e-10 39.7 7.1 1.5 1 0 0 1 1 1 1 HIT zinc finger adh_short PF00106.20 KUM66956.1 - 8.8e-18 64.7 0.0 1.2e-17 64.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM66956.1 - 6.6e-08 32.6 0.0 8.3e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM66956.1 - 2.9e-07 30.3 0.0 4.2e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KUM66956.1 - 0.00021 20.5 0.0 0.00026 20.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF460 PF04312.8 KUM66956.1 - 0.037 13.5 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF460) Toprim_3 PF13362.1 KUM66956.1 - 0.045 13.9 0.0 0.082 13.1 0.0 1.4 1 0 0 1 1 1 0 Toprim domain Tri3 PF07428.6 KUM66958.1 - 0.16 10.6 0.1 0.25 10.0 0.1 1.2 1 0 0 1 1 1 0 15-O-acetyltransferase Tri3 Herpes_DNAp_acc PF04929.7 KUM66958.1 - 0.19 10.6 0.0 0.19 10.6 0.0 2.2 2 1 0 2 2 2 0 Herpes DNA replication accessory factor PAXIP1_C PF15364.1 KUM66958.1 - 0.43 10.5 8.3 1.2 9.0 0.1 2.6 1 1 1 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein Ras PF00071.17 KUM66960.1 - 2.5e-48 163.5 0.0 3.2e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KUM66960.1 - 2.8e-12 47.1 0.0 4.2e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KUM66960.1 - 2.7e-05 23.4 0.0 0.00016 20.9 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KUM66960.1 - 0.041 13.0 0.0 0.065 12.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KUM66960.1 - 0.047 12.8 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PAP2 PF01569.16 KUM66961.1 - 2.6e-15 56.2 2.3 2.6e-15 56.2 1.6 1.9 1 1 0 1 1 1 1 PAP2 superfamily C5-epim_C PF06662.8 KUM66962.1 - 0.11 11.7 1.3 0.15 11.3 0.1 1.7 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus GILT PF03227.11 KUM66963.1 - 1.1e-08 34.8 0.3 4e-08 33.0 0.0 1.9 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Hexokinase_2 PF03727.11 KUM66964.1 - 2.5e-30 105.4 0.0 1.5e-24 86.5 0.0 2.4 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 KUM66964.1 - 1.2e-28 99.8 0.0 4.9e-27 94.6 0.0 2.8 1 1 0 1 1 1 1 Hexokinase RXT2_N PF08595.6 KUM66964.1 - 0.13 12.0 1.5 0.28 10.9 1.0 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Snf7 PF03357.16 KUM66964.1 - 0.44 9.9 4.9 1.1 8.6 3.4 1.7 1 0 0 1 1 1 0 Snf7 HeLo PF14479.1 KUM66966.1 - 2.2e-46 158.3 6.8 2.2e-46 158.3 4.7 2.2 2 0 0 2 2 2 1 Prion-inhibition and propagation DUF2205 PF10224.4 KUM66966.1 - 2.5 7.7 8.7 3.5 7.2 0.2 3.1 3 0 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) IZUMO PF15005.1 KUM66966.1 - 4 7.4 9.0 3.2 7.7 0.6 2.9 3 0 0 3 3 3 0 Izumo sperm-egg fusion WD40 PF00400.27 KUM66967.1 - 8.5e-88 285.4 30.2 2.3e-10 39.9 0.1 12.7 12 1 0 12 12 12 11 WD domain, G-beta repeat NACHT PF05729.7 KUM66967.1 - 1.1e-10 41.3 0.1 2.2e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 KUM66967.1 - 3.3e-08 32.9 11.4 4.8 6.9 0.0 9.1 11 0 0 11 11 11 3 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 KUM66967.1 - 1.1e-07 30.9 9.8 0.022 13.4 0.0 4.8 3 3 1 4 4 4 3 Nup133 N terminal like eIF2A PF08662.6 KUM66967.1 - 9.6e-05 22.1 0.5 0.21 11.2 0.0 4.5 1 1 3 4 4 4 1 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 KUM66967.1 - 0.015 13.5 0.8 1.3 7.1 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3312) Cytochrom_D1 PF02239.11 KUM66967.1 - 0.032 12.5 0.0 4.6 5.4 0.0 3.7 4 0 0 4 4 4 0 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 KUM66967.1 - 0.054 12.8 15.7 0.84 9.0 0.0 7.2 9 0 0 9 9 9 0 Proteasome subunit A N-terminal signature AAA_19 PF13245.1 KUM66967.1 - 0.09 12.5 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Speriolin_N PF15058.1 KUM66967.1 - 0.19 11.6 0.1 0.95 9.3 0.0 2.1 2 0 0 2 2 2 0 Speriolin N terminus MFS_1 PF07690.11 KUM66969.1 - 6.7e-36 123.7 24.3 6.7e-36 123.7 16.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 KUM66969.1 - 0.61 10.1 6.2 1.6 8.7 0.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) FAD_binding_4 PF01565.18 KUM66970.1 - 3.8e-17 62.0 0.0 9.8e-17 60.7 0.0 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KUM66970.1 - 1.8e-09 37.3 0.3 4.5e-09 36.0 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KUM66970.1 - 0.017 14.2 0.1 0.027 13.6 0.1 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding DUF676 PF05057.9 KUM66971.1 - 1.1e-07 31.4 0.0 1.8e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KUM66971.1 - 1e-06 28.7 0.0 1.8e-06 28.0 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KUM66971.1 - 1.6e-06 27.8 0.0 4.3e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KUM66971.1 - 0.0063 16.2 0.0 0.02 14.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_9 PF10081.4 KUM66971.1 - 0.025 13.2 0.0 0.035 12.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family DUF116 PF01976.12 KUM66971.1 - 0.19 11.2 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF116 PEMT PF04191.8 KUM66972.1 - 4.1e-59 197.2 7.5 2.2e-36 124.1 0.5 2.8 2 0 0 2 2 2 2 Phospholipid methyltransferase RNase_PH PF01138.16 KUM66973.1 - 9.1e-32 110.1 0.0 1.8e-31 109.2 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Allexi_40kDa PF05549.6 KUM66974.1 - 0.091 12.0 0.4 0.16 11.2 0.3 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein tRNA-synt_2b PF00587.20 KUM66975.1 - 3.1e-21 75.7 0.0 4.3e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.6 KUM66975.1 - 4.1e-21 74.6 1.6 1.1e-20 73.3 1.1 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 KUM66975.1 - 2.6e-10 40.1 0.0 1.3e-09 37.8 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain Cpn60_TCP1 PF00118.19 KUM66976.1 - 1.1e-141 472.7 15.4 1.3e-141 472.5 10.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_int_SAM_1 PF02899.12 KUM66976.1 - 0.065 13.3 0.1 1.1 9.5 0.0 2.8 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain WD40 PF00400.27 KUM66977.1 - 9.9e-25 85.4 4.4 6.7e-07 28.9 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Met_asp_mut_E PF06368.6 KUM66977.1 - 0.2 9.7 0.0 0.31 9.1 0.0 1.1 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) NmrA PF05368.8 KUM66978.1 - 4.8e-31 107.8 0.0 5.9e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KUM66978.1 - 4e-19 69.3 0.0 2.8e-18 66.5 0.0 2.0 1 1 1 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KUM66978.1 - 0.002 17.6 0.1 0.055 12.8 0.0 2.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KUM66978.1 - 0.0043 15.8 0.0 0.011 14.4 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 KUM66978.1 - 0.0093 15.8 0.0 0.065 13.1 0.0 2.2 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 KUM66978.1 - 0.014 14.4 0.1 0.021 13.7 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 KUM66978.1 - 0.036 12.9 0.1 0.24 10.3 0.1 2.1 2 1 0 2 2 2 0 Male sterility protein F420_oxidored PF03807.12 KUM66978.1 - 0.059 13.8 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sulfatase PF00884.18 KUM66980.1 - 1.6e-43 149.1 0.0 2e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KUM66980.1 - 9.4e-06 25.1 0.0 0.13 11.5 0.0 2.5 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KUM66980.1 - 0.057 11.8 0.0 0.085 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) bZIP_1 PF00170.16 KUM66981.1 - 1.4e-07 31.3 7.9 2.1e-07 30.7 5.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 KUM66981.1 - 0.00017 21.8 5.3 0.00025 21.2 3.7 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.10 KUM66981.1 - 0.00027 20.6 8.5 0.00039 20.1 5.9 1.2 1 0 0 1 1 1 1 Basic region leucine zipper DUF2353 PF09789.4 KUM66981.1 - 0.011 15.0 1.4 0.015 14.5 1.0 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Macoilin PF09726.4 KUM66981.1 - 0.032 12.5 1.9 0.042 12.1 1.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Ank_2 PF12796.2 KUM66982.1 - 2.7e-29 101.3 0.1 3.5e-10 40.0 0.0 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KUM66982.1 - 7.4e-24 83.6 0.4 5.9e-05 23.4 0.0 7.0 4 3 3 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.25 KUM66982.1 - 1.2e-22 78.5 0.1 0.0037 17.0 0.0 8.2 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.1 KUM66982.1 - 9.2e-19 65.6 0.2 0.023 14.8 0.0 8.1 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.1 KUM66982.1 - 1e-18 66.9 0.1 0.012 15.7 0.0 6.4 5 1 1 6 6 6 6 Ankyrin repeats (many copies) F-box PF00646.28 KUM66982.1 - 0.00057 19.4 0.1 0.0012 18.4 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KUM66982.1 - 0.00063 19.4 1.1 0.0013 18.3 0.7 1.5 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 KUM66982.1 - 0.022 14.4 0.1 0.06 13.0 0.1 1.7 1 0 0 1 1 1 0 F-box-like domain ADH_zinc_N PF00107.21 KUM66983.1 - 2.6e-29 101.3 0.5 4.3e-29 100.6 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM66983.1 - 1.2e-28 99.0 0.2 2e-28 98.3 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pyr_redox_3 PF13738.1 KUM66983.1 - 0.00023 21.2 0.0 0.002 18.2 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ADH_N_assoc PF13823.1 KUM66983.1 - 0.00027 20.5 0.0 0.00097 18.7 0.0 2.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated FAD_binding_3 PF01494.14 KUM66983.1 - 0.006 15.6 0.5 0.01 14.9 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.15 KUM66983.1 - 0.0063 16.6 0.6 0.016 15.3 0.1 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase CPSase_L_chain PF00289.17 KUM66983.1 - 0.065 13.3 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain 2-Hacid_dh_C PF02826.14 KUM66983.1 - 0.085 12.0 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 KUM66983.1 - 0.11 12.9 0.4 4.1 7.8 0.6 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 KUM66983.1 - 0.13 12.7 1.3 0.94 9.9 0.2 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Asp PF00026.18 KUM66984.1 - 1.7e-61 208.2 1.4 2.1e-61 207.9 1.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KUM66984.1 - 1e-05 25.9 0.0 0.12 12.8 0.1 2.9 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 KUM66984.1 - 0.00059 19.8 0.0 0.0019 18.2 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KUM66984.1 - 0.015 14.8 0.0 0.042 13.4 0.0 1.8 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal DUF4452 PF14618.1 KUM66985.1 - 5.6e-68 227.9 9.8 5.6e-68 227.9 6.8 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4452) Ank_2 PF12796.2 KUM66986.1 - 8.6e-26 90.1 0.3 2.5e-11 43.7 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KUM66986.1 - 1.7e-23 81.1 2.5 8.9e-08 31.5 0.2 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 KUM66986.1 - 5.5e-23 80.8 0.3 2.4e-09 37.4 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KUM66986.1 - 1.7e-19 69.3 1.8 7.3e-09 35.6 0.1 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KUM66986.1 - 6.6e-19 66.1 0.4 1.6e-05 24.6 0.1 5.2 5 0 0 5 5 5 4 Ankyrin repeat BCS1_N PF08740.6 KUM66986.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 BCS1 N terminal tRNA_bind PF01588.15 KUM66987.1 - 1.4e-22 79.3 0.0 1.5e-20 72.7 0.0 2.4 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 KUM66987.1 - 2.3e-08 34.4 0.0 7.9e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KUM66987.1 - 3.9e-05 23.4 0.0 0.0003 20.6 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KUM66987.1 - 0.024 14.6 0.2 0.072 13.0 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain NPR3 PF03666.8 KUM66987.1 - 0.097 11.1 1.6 0.14 10.6 1.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.7 KUM66987.1 - 0.34 10.7 7.3 0.53 10.1 5.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Anp1 PF03452.9 KUM66988.1 - 8.6e-121 402.2 0.0 1.2e-120 401.7 0.0 1.2 1 0 0 1 1 1 1 Anp1 adh_short PF00106.20 KUM66989.1 - 1.6e-13 50.9 0.0 2.4e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KUM66989.1 - 8.7e-09 35.2 0.0 1.3e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KUM66989.1 - 0.015 14.7 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KUM66989.1 - 0.049 12.5 0.1 0.8 8.5 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KUM66989.1 - 0.13 11.1 0.1 0.43 9.4 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein CRCB PF02537.10 KUM66991.1 - 4.4e-28 97.5 26.9 2.9e-18 65.8 4.8 3.8 3 1 0 3 3 3 2 CrcB-like protein RNA_pol_Rpc4 PF05132.9 KUM66992.1 - 3.5e-33 114.3 0.0 3.5e-33 114.3 0.0 3.4 4 1 1 5 5 5 1 RNA polymerase III RPC4 Ribosomal_60s PF00428.14 KUM66992.1 - 3.9 7.9 15.7 0.87 10.0 4.9 3.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein Cyclin_N PF00134.18 KUM66994.1 - 2.5e-42 143.4 0.1 5.7e-42 142.2 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KUM66994.1 - 9e-29 99.7 0.0 2.1e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Zn_clus PF00172.13 KUM66995.1 - 0.0035 17.2 13.0 0.0065 16.3 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 KUM66995.1 - 0.049 12.8 0.0 0.16 11.2 0.0 1.9 1 0 0 1 1 1 0 Histone chaperone domain CHZ HA2 PF04408.18 KUM66996.1 - 1.4e-19 70.0 0.5 4.3e-19 68.4 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KUM66996.1 - 1.2e-17 63.7 0.0 2.3e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RWD PF05773.17 KUM66996.1 - 5.3e-14 52.0 0.0 1.1e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 RWD domain Helicase_C PF00271.26 KUM66996.1 - 8.4e-13 47.9 0.0 2.1e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KUM66996.1 - 6.4e-10 38.7 0.0 1.1e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KUM66996.1 - 0.00031 20.9 0.9 0.002 18.2 0.6 2.2 1 1 0 1 1 1 1 AAA domain DND1_DSRM PF14709.1 KUM66996.1 - 0.0035 17.6 0.0 0.0091 16.2 0.0 1.7 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 T2SE PF00437.15 KUM66996.1 - 0.0035 16.3 0.0 0.0065 15.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 KUM66996.1 - 0.0037 16.7 0.0 0.0081 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain PhoH PF02562.11 KUM66996.1 - 0.0077 15.4 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein KaiC PF06745.8 KUM66996.1 - 0.014 14.5 0.1 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 KUM66996.1 - 0.03 14.6 0.2 0.065 13.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 KUM66996.1 - 0.036 13.9 0.0 0.16 11.7 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.13 KUM66996.1 - 0.039 13.4 0.0 0.18 11.2 0.0 2.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zot PF05707.7 KUM66996.1 - 0.077 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF2417 PF10329.4 KUM66997.1 - 0.053 12.9 11.0 0.064 12.6 7.6 1.0 1 0 0 1 1 1 0 Region of unknown function (DUF2417) TRAP_alpha PF03896.11 KUM66998.1 - 5.4e-13 48.5 0.1 9.1e-13 47.8 0.1 1.5 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DcpS_C PF11969.3 KUM66999.1 - 2.3e-17 63.2 5.1 1.8e-16 60.4 3.6 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 KUM66999.1 - 2.3e-17 63.2 0.7 5.9e-17 62.0 0.5 1.7 1 1 0 1 1 1 1 HIT domain MoCF_biosynth PF00994.19 KUM67000.1 - 5.5e-48 162.0 0.0 2.7e-25 88.4 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 KUM67000.1 - 6.8e-36 123.0 1.3 1e-35 122.5 0.9 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 KUM67000.1 - 7e-14 51.5 0.3 2.3e-13 49.8 0.1 2.1 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) DDHD PF02862.12 KUM67001.1 - 1.1e-44 152.9 0.7 4.1e-42 144.5 0.0 3.2 2 2 0 2 2 2 1 DDHD domain Abhydrolase_5 PF12695.2 KUM67001.1 - 0.0062 16.3 0.0 0.017 14.8 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KUM67001.1 - 0.0079 16.0 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family FAD_binding_3 PF01494.14 KUM67003.1 - 1.4e-71 241.4 0.0 1.8e-71 241.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KUM67003.1 - 2e-38 131.6 0.1 3.2e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 KUM67003.1 - 0.0082 15.0 0.0 0.018 13.9 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KUM67003.1 - 0.01 16.2 0.0 0.028 14.8 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KUM67003.1 - 0.02 13.7 0.1 0.065 12.1 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 KUM67003.1 - 0.037 14.0 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KUM67003.1 - 0.038 13.0 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family GDI PF00996.13 KUM67003.1 - 0.063 11.5 0.0 0.097 10.9 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Pyr_redox_2 PF07992.9 KUM67003.1 - 0.098 12.5 0.0 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KUM67003.1 - 0.099 12.0 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF866 PF05907.8 KUM67004.1 - 6.5e-47 159.0 0.1 7.1e-47 158.8 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Cytochrome_C7 PF14522.1 KUM67004.1 - 0.031 13.8 1.0 0.055 13.1 0.7 1.4 1 0 0 1 1 1 0 Cytochrome c7 Paired_CXXCH_1 PF09699.5 KUM67004.1 - 0.11 12.0 0.1 0.11 12.0 0.1 1.6 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) LSM PF01423.17 KUM67005.1 - 3.1e-16 58.6 0.0 3.6e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain RTA1 PF04479.8 KUM67007.1 - 8.6e-25 87.5 3.8 9.7e-25 87.3 2.6 1.0 1 0 0 1 1 1 1 RTA1 like protein 7TMR-DISM_7TM PF07695.6 KUM67007.1 - 0.048 13.3 2.7 0.061 12.9 1.9 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling DUF687 PF05095.7 KUM67007.1 - 0.1 10.9 0.2 0.16 10.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF687) EmrE PF13536.1 KUM67008.1 - 0.044 13.9 1.1 0.051 13.7 0.8 1.1 1 0 0 1 1 1 0 Multidrug resistance efflux transporter DUF4131 PF13567.1 KUM67008.1 - 0.75 9.1 2.8 0.87 8.9 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DASH_Dad1 PF08649.5 KUM67009.1 - 3.2e-23 81.1 2.1 4e-23 80.8 1.5 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DUF92 PF01940.11 KUM67011.1 - 1.3e-59 201.0 8.9 1.6e-59 200.7 6.1 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 TMEM154 PF15102.1 KUM67012.1 - 0.00011 21.9 1.6 0.00011 21.9 1.1 1.1 1 0 0 1 1 1 1 TMEM154 protein family ASFV_J13L PF05568.6 KUM67012.1 - 0.00021 20.8 0.1 0.00023 20.7 0.1 1.0 1 0 0 1 1 1 1 African swine fever virus J13L protein SP_C-Propep PF08999.5 KUM67012.1 - 0.00057 19.3 0.3 0.00075 18.9 0.2 1.2 1 0 0 1 1 1 1 Surfactant protein C, N terminal propeptide P12 PF12669.2 KUM67012.1 - 0.0075 16.4 0.7 0.01 15.9 0.5 1.2 1 0 0 1 1 1 1 Virus attachment protein p12 family RCR PF12273.3 KUM67012.1 - 0.01 16.4 0.3 0.013 16.0 0.2 1.2 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF4010 PF13194.1 KUM67012.1 - 0.014 14.6 0.1 0.016 14.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) EphA2_TM PF14575.1 KUM67012.1 - 0.02 15.2 0.0 0.024 15.0 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1510 PF07423.6 KUM67012.1 - 0.062 12.6 0.2 0.069 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) ODV-E18 PF10717.4 KUM67012.1 - 0.065 12.6 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Shisa PF13908.1 KUM67012.1 - 0.07 13.3 0.0 0.082 13.0 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Afaf PF15339.1 KUM67012.1 - 0.1 12.1 0.0 0.12 11.9 0.0 1.0 1 0 0 1 1 1 0 Acrosome formation-associated factor DUF929 PF06053.6 KUM67012.1 - 0.13 11.3 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF929) DUF3377 PF11857.3 KUM67012.1 - 0.17 11.5 1.1 0.23 11.1 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Baculo_11_kDa PF06143.6 KUM67012.1 - 0.27 10.6 1.9 0.36 10.2 1.3 1.1 1 0 0 1 1 1 0 Baculovirus 11 kDa family Vpu PF00558.14 KUM67012.1 - 0.29 10.6 1.4 0.36 10.4 0.9 1.1 1 0 0 1 1 1 0 Vpu protein ADH_zinc_N PF00107.21 KUM67013.1 - 1.2e-08 34.5 0.3 3.9e-08 32.9 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KUM67013.1 - 3e-08 33.4 0.0 1.7e-07 30.9 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Na_Ca_ex PF01699.19 KUM67014.1 - 2.2e-19 69.4 30.8 1.8e-10 40.5 5.4 2.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein CoxIIa PF08113.6 KUM67014.1 - 0.011 15.4 4.5 0.078 12.7 3.1 2.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family Na_Ca_ex PF01699.19 KUM67015.1 - 6.9e-36 122.9 34.2 3.7e-19 68.7 5.1 2.9 2 1 1 3 3 3 2 Sodium/calcium exchanger protein SBF PF01758.11 KUM67015.1 - 0.0028 17.0 2.5 0.0028 17.0 1.7 2.5 2 0 0 2 2 2 1 Sodium Bile acid symporter family TPR_10 PF13374.1 KUM67016.1 - 3.1e-76 249.3 4.2 3.8e-10 39.3 0.0 8.9 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 KUM67016.1 - 3.8e-73 241.4 11.9 8.3e-14 51.2 0.1 6.7 2 2 6 8 8 8 8 Tetratricopeptide repeat TPR_7 PF13176.1 KUM67016.1 - 1.9e-17 61.5 7.3 0.14 11.9 0.1 7.0 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_17 PF13431.1 KUM67016.1 - 9.1e-14 50.4 3.8 1.5 9.2 0.0 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 KUM67016.1 - 1.4e-13 51.0 1.9 0.00025 21.6 0.1 5.5 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 KUM67016.1 - 3.7e-13 48.3 3.3 0.075 12.9 0.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 KUM67016.1 - 2e-12 46.1 0.2 0.26 10.9 0.0 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 KUM67016.1 - 3.4e-12 45.8 1.1 0.0074 15.9 0.0 5.5 3 2 3 6 6 6 5 TPR repeat TPR_4 PF07721.9 KUM67016.1 - 2.8e-11 42.7 4.9 0.016 15.5 0.4 6.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KUM67016.1 - 5.3e-09 35.2 1.1 2.4 8.1 0.1 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KUM67016.1 - 6.9e-08 32.4 12.2 0.55 11.0 0.2 6.8 4 3 2 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KUM67016.1 - 5.1e-07 29.9 7.3 0.83 10.0 0.2 6.3 4 3 3 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 KUM67016.1 - 1.7e-05 24.9 13.4 0.94 10.0 0.1 7.0 8 0 0 8 8 6 2 Tetratricopeptide repeat Apc3 PF12895.2 KUM67016.1 - 0.00064 19.8 0.1 0.65 10.1 0.0 3.8 1 1 5 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 DUF4074 PF13293.1 KUM67016.1 - 0.019 15.1 0.1 11 6.2 0.0 4.0 5 0 0 5 5 4 0 Domain of unknown function (DUF4074) DUF2664 PF10867.3 KUM67016.1 - 0.03 14.9 1.4 11 6.6 0.0 4.9 4 1 2 6 6 5 0 Protein of unknown function (DUF2664) DUF3366 PF11846.3 KUM67016.1 - 0.47 10.3 5.0 6.7 6.5 0.1 3.5 2 1 1 4 4 4 0 Domain of unknown function (DUF3366) Na_Ca_ex PF01699.19 KUM67017.1 - 4.1e-23 81.5 28.8 1.3e-12 47.5 6.0 2.4 2 1 0 2 2 2 2 Sodium/calcium exchanger protein WND PF07861.6 KUM67017.1 - 0.012 14.6 2.3 0.016 14.2 0.1 2.0 2 0 0 2 2 2 0 WisP family N-Terminal Region PHO4 PF01384.15 KUM67018.1 - 7.5e-103 343.6 17.7 8.7e-103 343.3 12.3 1.0 1 0 0 1 1 1 1 Phosphate transporter family DUF486 PF04342.7 KUM67018.1 - 0.012 15.6 0.3 0.1 12.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF486 Syndecan PF01034.15 KUM67018.1 - 0.11 12.1 1.2 0.32 10.6 0.0 2.4 2 0 0 2 2 2 0 Syndecan domain PgpA PF04608.8 KUM67018.1 - 0.66 9.7 7.0 0.27 11.0 0.6 2.8 3 0 0 3 3 3 0 Phosphatidylglycerophosphatase A E1-E2_ATPase PF00122.15 KUM67019.1 - 1.8e-60 203.8 5.2 2.6e-60 203.3 0.2 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KUM67019.1 - 2.8e-44 150.8 9.3 2.8e-44 150.8 6.5 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KUM67019.1 - 2.5e-24 86.8 0.0 1.2e-23 84.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KUM67019.1 - 4.1e-17 62.9 0.0 1.6e-16 61.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KUM67019.1 - 6e-17 61.3 0.0 1.5e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KUM67019.1 - 9e-07 28.2 1.3 3.3e-06 26.4 0.0 2.6 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus YjgP_YjgQ PF03739.9 KUM67019.1 - 0.0023 16.7 2.5 0.0023 16.7 1.8 2.1 2 1 0 2 2 2 1 Predicted permease YjgP/YjgQ family Hydrolase_3 PF08282.7 KUM67019.1 - 0.011 15.3 0.2 0.027 14.0 0.1 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DevR PF01905.11 KUM67019.1 - 0.052 12.3 0.0 0.077 11.8 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 DUF202 PF02656.10 KUM67019.1 - 0.2 11.9 0.0 0.2 11.9 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF202) Exo_endo_phos PF03372.18 KUM67020.1 - 6.6e-09 36.0 1.9 9.7e-09 35.5 1.3 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Jacalin PF01419.12 KUM67020.1 - 0.00039 20.3 0.2 0.00085 19.2 0.1 1.6 1 0 0 1 1 1 1 Jacalin-like lectin domain SNARE PF05739.14 KUM67023.1 - 1.1e-12 47.4 2.7 2.5e-12 46.2 1.9 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 KUM67023.1 - 0.045 13.9 1.2 0.1 12.7 0.0 2.1 2 1 0 2 2 2 0 Syntaxin Phage_GP20 PF06810.6 KUM67023.1 - 0.085 12.2 1.8 5 6.5 0.1 2.4 2 0 0 2 2 2 0 Phage minor structural protein GP20 HrpB7 PF09486.5 KUM67023.1 - 0.12 12.2 0.3 0.12 12.2 0.2 2.3 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Snapin_Pallidin PF14712.1 KUM67023.1 - 0.13 12.6 0.6 7.8 6.8 0.0 2.5 2 0 0 2 2 2 0 Snapin/Pallidin DUF3138 PF11336.3 KUM67023.1 - 0.15 10.1 0.8 0.19 9.8 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF1664 PF07889.7 KUM67023.1 - 0.16 11.8 1.0 0.27 11.0 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Synaptobrevin PF00957.16 KUM67023.1 - 0.29 10.7 2.3 0.83 9.2 1.6 1.8 1 0 0 1 1 1 0 Synaptobrevin FlxA PF14282.1 KUM67023.1 - 2.5 8.0 6.1 0.16 11.9 0.2 1.9 2 0 0 2 2 2 0 FlxA-like protein zf-TRAF PF02176.13 KUM67024.1 - 1.4e-12 47.7 29.3 4.5e-08 33.3 3.1 4.2 1 1 3 4 4 4 4 TRAF-type zinc finger zf-RING_2 PF13639.1 KUM67024.1 - 9.6e-07 28.5 11.8 9.6e-07 28.5 8.2 3.9 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 KUM67024.1 - 1.3e-06 27.9 10.4 1.3e-06 27.9 7.2 3.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KUM67024.1 - 2.4e-06 27.3 12.9 2.4e-06 27.3 8.9 2.9 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KUM67024.1 - 2.6e-06 27.0 6.9 9.7e-06 25.2 4.8 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 KUM67024.1 - 1.8e-05 24.3 10.3 1.8e-05 24.3 7.2 3.5 2 1 1 3 3 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KUM67024.1 - 2.4e-05 24.2 11.8 2.4e-05 24.2 8.2 3.6 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KUM67024.1 - 9.2e-05 22.0 9.9 9.2e-05 22.0 6.9 3.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) KxDL PF10241.4 KUM67024.1 - 0.1 12.5 0.7 0.43 10.5 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein TraP PF07296.6 KUM67024.1 - 0.12 11.2 0.9 0.26 10.2 0.6 1.5 1 0 0 1 1 1 0 TraP protein Sina PF03145.11 KUM67024.1 - 0.25 10.9 19.7 0.25 10.9 0.4 3.1 1 1 0 2 2 2 0 Seven in absentia protein family Fungal_trans PF04082.13 KUM67025.1 - 1.8e-15 56.5 1.1 3e-15 55.8 0.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KUM67025.1 - 9.2e-11 41.4 7.9 1.8e-10 40.5 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kinesin PF00225.18 KUM67028.1 - 2e-59 200.9 0.3 5.9e-33 113.9 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain ParA PF10609.4 KUM67029.1 - 3.7e-36 122.8 0.0 1.2e-35 121.2 0.0 1.8 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 KUM67029.1 - 1.4e-16 60.4 0.0 2e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KUM67029.1 - 1.6e-06 28.1 0.0 7.6e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 KUM67029.1 - 5e-06 25.7 0.9 0.00035 19.7 0.1 2.8 2 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 KUM67029.1 - 0.00097 18.2 0.0 0.0027 16.8 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.1 KUM67029.1 - 0.0011 18.6 0.0 0.45 10.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KUM67029.1 - 0.0097 15.1 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KUM67029.1 - 0.012 15.0 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KUM67029.1 - 0.026 14.0 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.13 KUM67029.1 - 0.04 13.1 0.0 1 8.4 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_17 PF13207.1 KUM67029.1 - 0.073 13.8 0.1 0.2 12.5 0.0 1.7 2 1 0 2 2 1 0 AAA domain AAA_19 PF13245.1 KUM67029.1 - 0.13 12.0 0.1 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain T2SE PF00437.15 KUM67029.1 - 0.15 10.9 0.1 0.26 10.1 0.0 1.4 2 0 0 2 2 2 0 Type II/IV secretion system protein RNA_helicase PF00910.17 KUM67029.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 KUM67029.1 - 0.16 12.0 0.0 0.37 10.9 0.0 1.6 2 0 0 2 2 1 0 AAA domain Zn_Tnp_IS1595 PF12760.2 KUM67029.1 - 0.18 11.6 0.1 0.18 11.6 0.1 1.9 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF605 PF04652.11 KUM67031.1 - 0.012 15.0 5.2 0.017 14.5 3.6 1.2 1 0 0 1 1 1 0 Vta1 like DUF1319 PF07028.6 KUM67031.1 - 0.037 14.2 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) Nop14 PF04147.7 KUM67031.1 - 0.093 10.6 5.9 0.13 10.2 4.1 1.2 1 0 0 1 1 1 0 Nop14-like family Trypan_PARP PF05887.6 KUM67031.1 - 0.31 10.8 9.7 0.52 10.1 6.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TPR_11 PF13414.1 KUM67032.1 - 0.0013 18.3 0.4 0.66 9.6 0.0 3.3 3 0 0 3 3 3 1 TPR repeat Apc3 PF12895.2 KUM67032.1 - 0.022 14.8 0.3 18 5.5 0.1 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 KUM67032.1 - 0.026 14.4 0.2 0.45 10.5 0.0 3.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Methyltransf_33 PF10017.4 KUM67033.1 - 3.2e-27 94.9 0.1 9.2e-27 93.4 0.0 1.9 2 0 0 2 2 2 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 KUM67033.1 - 5.8e-12 45.5 0.1 1.2e-11 44.5 0.1 1.4 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 KUM67033.1 - 1.4e-07 31.9 1.3 3e-07 30.8 0.9 1.6 1 0 0 1 1 1 1 DinB superfamily Methyltransf_25 PF13649.1 KUM67033.1 - 0.0035 17.6 0.0 0.0077 16.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Aldedh PF00171.17 KUM67034.1 - 1.6e-135 452.0 0.1 1.8e-135 451.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KUM67034.1 - 2.6e-08 33.0 0.0 4.3e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) ATP-synt_D PF01813.12 KUM67034.1 - 0.046 13.2 0.1 0.072 12.6 0.1 1.3 1 0 0 1 1 1 0 ATP synthase subunit D Nsp1_C PF05064.8 KUM67034.1 - 0.23 11.0 1.6 0.48 10.0 1.1 1.4 1 0 0 1 1 1 0 Nsp1-like C-terminal region LigT_PEase PF02834.11 KUM67035.1 - 0.066 13.2 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 LigT like Phosphoesterase Dabb PF07876.7 KUM67037.1 - 2e-26 92.2 0.1 2.2e-26 92.1 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain TFIIA_gamma_C PF02751.9 KUM67040.1 - 6.8e-28 96.2 2.2 8.7e-28 95.9 1.5 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 KUM67040.1 - 0.033 13.7 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain S1 PF00575.18 KUM67042.1 - 1.4e-82 271.7 24.5 1.3e-17 63.5 1.0 12.8 13 0 0 13 13 13 10 S1 RNA binding domain TPR_19 PF14559.1 KUM67042.1 - 4.5e-08 33.3 0.3 0.012 15.9 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KUM67042.1 - 6.1e-08 33.1 0.6 0.23 12.1 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat Suf PF05843.9 KUM67042.1 - 1.6e-06 28.0 16.0 0.0031 17.3 0.0 5.0 3 1 2 5 5 5 3 Suppressor of forked protein (Suf) TPR_14 PF13428.1 KUM67042.1 - 6.2e-06 26.3 6.0 0.71 10.6 0.7 5.6 2 1 5 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.1 KUM67042.1 - 0.001 18.1 1.8 0.19 10.7 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 KUM67042.1 - 0.0017 18.1 0.2 0.0032 17.2 0.1 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 TPR_12 PF13424.1 KUM67042.1 - 0.017 15.0 0.8 1.2 9.1 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.15 KUM67042.1 - 0.024 14.5 0.3 12 6.1 0.0 3.7 3 0 0 3 3 3 0 PPR repeat CDC27 PF09507.5 KUM67042.1 - 8.1 5.5 39.7 0.71 9.0 14.0 2.6 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 MFS_1 PF07690.11 KUM67043.1 - 4.6e-07 28.8 6.1 6.4e-05 21.8 0.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KUM67044.1 - 1.4e-81 274.4 21.6 1.6e-81 274.2 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KUM67044.1 - 1.7e-18 66.4 18.1 1.7e-18 66.4 12.6 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Mtr2 PF10429.4 KUM67044.1 - 0.027 14.2 0.0 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 CybS PF05328.7 KUM67044.1 - 0.069 12.7 0.5 0.19 11.3 0.4 1.7 1 0 0 1 1 1 0 CybS DUF1049 PF06305.6 KUM67044.1 - 2.1 7.8 6.1 10 5.6 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) Arm PF00514.18 KUM67045.1 - 3.2e-90 293.2 11.7 3.6e-14 51.9 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.15 KUM67045.1 - 2.7e-22 78.7 5.1 4.7e-22 77.9 3.5 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.1 KUM67045.1 - 2.7e-22 78.8 0.3 5.5e-09 36.1 0.0 5.6 1 1 5 6 6 6 4 HEAT repeats HEAT_EZ PF13513.1 KUM67045.1 - 2.5e-19 69.1 8.6 2.4e-09 37.4 0.0 6.1 6 1 1 7 7 7 3 HEAT-like repeat HEAT PF02985.17 KUM67045.1 - 5.1e-18 63.4 0.1 1.1e-06 28.1 0.0 7.0 7 0 0 7 7 7 3 HEAT repeat Arm_2 PF04826.8 KUM67045.1 - 2.6e-11 43.1 0.0 0.00056 19.0 0.0 4.2 2 1 2 4 4 4 2 Armadillo-like V-ATPase_H_C PF11698.3 KUM67045.1 - 0.00013 21.8 0.0 1.2 9.0 0.0 4.6 4 1 0 4 4 4 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 KUM67045.1 - 0.0058 14.9 0.0 0.48 8.6 0.0 2.9 2 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 KUM67045.1 - 0.026 14.9 1.4 1.2 9.8 0.0 4.1 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat STAG PF08514.6 KUM67046.1 - 1.6e-37 127.7 0.4 4.5e-37 126.3 0.3 1.8 1 0 0 1 1 1 1 STAG domain Nipped-B_C PF12830.2 KUM67046.1 - 0.016 14.8 0.0 0.055 13.1 0.0 1.9 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus MIF4G PF02854.14 KUM67046.1 - 0.027 13.8 0.0 0.29 10.5 0.0 2.4 2 0 0 2 2 2 0 MIF4G domain HEAT_2 PF13646.1 KUM67046.1 - 0.03 14.5 2.5 0.059 13.6 0.1 2.7 3 0 0 3 3 3 0 HEAT repeats Pox_Ag35 PF03286.9 KUM67046.1 - 0.088 12.3 0.1 0.088 12.3 0.1 5.2 5 1 1 6 6 6 0 Pox virus Ag35 surface protein Sas10_Utp3 PF04000.10 KUM67046.1 - 0.26 11.4 5.2 0.91 9.7 0.0 4.0 3 1 1 4 4 4 0 Sas10/Utp3/C1D family FlgM PF04316.8 KUM67046.1 - 0.3 11.0 5.6 0.12 12.2 1.4 2.3 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM ABC_tran PF00005.22 KUM67047.1 - 1.2e-17 64.4 0.0 2.4e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KUM67047.1 - 3.6e-12 46.2 4.8 3.6e-12 46.2 3.3 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 KUM67047.1 - 0.0001 21.6 0.0 0.038 13.2 0.0 2.3 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KUM67047.1 - 0.0005 19.5 0.0 0.0014 18.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KUM67047.1 - 0.044 13.7 0.0 0.12 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.18 KUM67047.1 - 0.057 13.2 0.1 0.098 12.4 0.1 1.3 1 0 0 1 1 1 0 Dynamin family AAA_23 PF13476.1 KUM67047.1 - 0.23 11.7 0.0 0.43 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain UreD PF01774.12 KUM67048.1 - 1.2e-58 198.0 0.0 8.8e-58 195.2 0.0 1.9 1 1 0 1 1 1 1 UreD urease accessory protein DUF1764 PF08576.5 KUM67050.1 - 0.18 12.5 3.4 9.6 7.0 0.1 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Cyclin_N PF00134.18 KUM67051.1 - 1e-10 41.2 0.1 3.3e-10 39.6 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Glyco_transf_43 PF03360.11 KUM67052.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 43 adh_short PF00106.20 KUM67053.1 - 2.3e-27 95.9 0.9 3.2e-27 95.4 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KUM67053.1 - 1.1e-26 94.1 0.0 1.4e-26 93.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KUM67053.1 - 6.4e-15 55.2 0.2 9.7e-15 54.6 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_2 PF03446.10 KUM67053.1 - 0.046 13.5 0.0 0.23 11.2 0.0 2.0 1 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Lipocalin_3 PF12702.2 KUM67053.1 - 0.074 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipocalin-like Pyr_redox PF00070.22 KUM67053.1 - 0.099 13.0 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Spc97_Spc98 PF04130.8 KUM67054.1 - 1e-81 274.8 0.0 2.3e-81 273.7 0.0 1.5 1 1 0 1 1 1 1 Spc97 / Spc98 family LrgB PF04172.11 KUM67055.1 - 0.094 11.8 2.6 0.19 10.8 0.1 2.0 2 0 0 2 2 2 0 LrgB-like family DUF2839 PF10999.3 KUM67055.1 - 8.5 6.4 7.9 1.7 8.7 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2839) DEAD PF00270.24 KUM67056.1 - 1.1e-19 70.5 0.0 2.7e-19 69.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KUM67056.1 - 3.8e-09 36.6 0.0 2.7e-08 33.8 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KUM67056.1 - 2.6e-06 27.1 0.1 9.7e-06 25.3 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.11 KUM67056.1 - 0.047 12.9 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein tify PF06200.9 KUM67056.1 - 0.076 12.2 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 tify domain GST_N_2 PF13409.1 KUM67057.1 - 1.3e-22 79.5 0.0 3.3e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KUM67057.1 - 3.6e-18 65.2 0.2 3.6e-17 62.0 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KUM67057.1 - 1.1e-07 31.7 0.0 1.9e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KUM67057.1 - 2.5e-06 27.9 0.0 4.8e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KUM67057.1 - 2.7e-06 27.4 0.1 0.00019 21.6 0.1 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Mito_carr PF00153.22 KUM67058.1 - 3e-68 225.5 4.4 3.8e-22 77.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 KUM67058.1 - 1.1e-06 27.5 0.3 2.8e-06 26.2 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KUM67058.1 - 2.4e-05 24.3 0.0 4.5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 KUM67058.1 - 4.9e-05 22.8 0.0 0.00011 21.7 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KUM67058.1 - 9.8e-05 21.5 0.2 0.00019 20.6 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KUM67058.1 - 0.0002 20.9 0.1 0.00054 19.6 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain ThiF PF00899.16 KUM67060.1 - 7e-52 174.8 0.0 1.5e-29 102.5 0.0 2.6 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 KUM67060.1 - 1.7e-39 133.1 1.6 1.2e-25 88.8 0.2 2.5 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 KUM67060.1 - 2.1e-38 131.2 0.0 5e-38 130.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 KUM67060.1 - 5.4e-24 83.3 2.2 5.7e-21 73.6 0.4 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site