# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- rve PF00665.26 KZN83379.1 - 4.1e-10 39.9 0.0 9.9e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 KZN83379.1 - 2.4e-05 24.1 0.0 6.2e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain Retrotran_gag_3 PF14244.6 KZN83380.1 - 0.013 15.3 0.0 0.22 11.4 0.0 2.4 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type p450 PF00067.22 KZN83381.1 - 6.9e-38 130.6 0.0 9.4e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ring_hydroxyl_A PF00848.19 KZN83382.1 - 3.3e-24 86.1 6.4 7.1e-13 49.0 0.0 2.2 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KZN83382.1 - 6.7e-15 54.8 0.0 1.4e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain MR_MLE_C PF13378.6 KZN83384.1 - 3.2e-50 170.7 0.1 4.9e-50 170.1 0.1 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KZN83384.1 - 0.00015 21.9 0.0 0.00032 20.9 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Epimerase PF01370.21 KZN83385.1 - 2.3e-12 46.9 0.1 6.1e-09 35.7 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KZN83385.1 - 4.3e-11 42.4 0.0 2.3e-06 26.8 0.1 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KZN83385.1 - 2e-10 40.8 0.0 2.9e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KZN83385.1 - 6.4e-08 32.4 0.1 1.2e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KZN83385.1 - 3.7e-07 29.6 0.0 0.015 14.5 0.1 2.2 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KZN83385.1 - 5.7e-07 29.2 0.0 9.2e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KZN83385.1 - 9.6e-06 25.2 0.0 2.5e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN83385.1 - 0.00021 21.3 0.0 0.0037 17.2 0.0 2.3 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KZN83385.1 - 0.046 12.8 0.3 0.23 10.5 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Sugar_tr PF00083.24 KZN83386.1 - 1.8e-106 356.7 14.2 2.1e-106 356.5 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN83386.1 - 1.3e-24 86.8 6.5 1.3e-24 86.8 6.5 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KZN83386.1 - 7.2e-05 21.8 1.7 0.0032 16.4 0.0 2.7 2 2 1 3 3 3 3 MFS_1 like family ATP-grasp_3 PF02655.14 KZN83387.1 - 2.6e-06 27.6 0.0 4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KZN83387.1 - 2.2e-05 24.1 0.0 0.00024 20.8 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.22 KZN83387.1 - 0.00022 20.8 0.0 0.00059 19.4 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 KZN83387.1 - 0.00089 18.6 0.0 0.018 14.3 0.0 2.1 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp GARS_A PF01071.19 KZN83387.1 - 0.0022 17.8 0.0 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CP_ATPgrasp_1 PF04174.13 KZN83387.1 - 0.031 13.3 0.0 0.99 8.4 0.0 2.5 2 1 1 3 3 3 0 A circularly permuted ATPgrasp CP_ATPgrasp_2 PF14403.6 KZN83387.1 - 0.067 12.1 0.0 0.19 10.6 0.0 1.7 2 0 0 2 2 2 0 Circularly permuted ATP-grasp type 2 Pyr_redox_2 PF07992.14 KZN83388.1 - 1.2e-33 116.7 0.0 1.5e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KZN83388.1 - 4.2e-14 52.9 0.0 5e-11 43.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KZN83388.1 - 1.7e-08 34.1 0.0 3.5e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KZN83388.1 - 8e-08 32.2 0.0 0.08 12.5 0.0 4.0 3 1 1 4 4 4 3 FAD dependent oxidoreductase K_oxygenase PF13434.6 KZN83388.1 - 1.9e-06 27.2 0.1 5.9e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 KZN83388.1 - 5.5e-06 26.8 0.0 0.0004 20.8 0.0 2.9 3 0 0 3 3 3 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 KZN83388.1 - 5.8e-06 26.4 0.0 0.0095 16.2 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KZN83388.1 - 9.9e-06 25.6 0.1 2.2 8.3 0.0 4.2 4 0 0 4 4 4 2 FAD-NAD(P)-binding TrkA_N PF02254.18 KZN83388.1 - 0.00011 22.4 0.5 0.055 13.7 0.0 3.5 4 0 0 4 4 4 1 TrkA-N domain Trp_halogenase PF04820.14 KZN83388.1 - 0.00061 18.8 0.0 0.24 10.2 0.1 2.4 2 1 0 2 2 2 2 Tryptophan halogenase DUF1188 PF06690.11 KZN83388.1 - 0.012 15.2 0.0 2.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) Lycopene_cycl PF05834.12 KZN83388.1 - 0.034 13.2 0.1 0.24 10.4 0.0 2.2 3 0 0 3 3 3 0 Lycopene cyclase protein ApbA PF02558.16 KZN83388.1 - 0.04 13.6 0.0 0.45 10.1 0.0 2.7 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 KZN83388.1 - 0.16 12.2 0.1 21 5.4 0.0 2.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain SGL PF08450.12 KZN83389.1 - 4.8e-09 36.2 0.1 0.0037 16.9 0.0 3.1 2 1 1 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region Oxidored_FMN PF00724.20 KZN83390.1 - 8.7e-38 130.4 0.0 1.1e-37 130.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family UPF0160 PF03690.13 KZN83390.1 - 0.013 15.2 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) Band_7 PF01145.25 KZN83390.1 - 0.078 13.0 0.1 1.2 9.2 0.2 2.6 2 1 0 2 2 2 0 SPFH domain / Band 7 family Fungal_trans PF04082.18 KZN83391.1 - 1.5e-13 50.4 0.0 2e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain CoA_transf_3 PF02515.17 KZN83392.1 - 4.8e-108 361.6 0.1 5.4e-108 361.4 0.1 1.0 1 0 0 1 1 1 1 CoA-transferase family III Fungal_trans PF04082.18 KZN83393.1 - 5.1e-08 32.3 2.8 6.3e-07 28.7 2.8 2.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF3716 PF12511.8 KZN83394.1 - 1.6e-10 40.8 2.7 2.9e-10 40.0 2.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF2406 PF10295.9 KZN83396.1 - 1.6e-24 86.3 0.7 2.4e-24 85.8 0.7 1.2 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) Glyco_hydro_72 PF03198.14 KZN83397.1 - 9.2e-120 399.6 6.5 8.6e-119 396.4 6.5 2.0 1 1 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KZN83397.1 - 1.1e-25 90.1 7.6 1.1e-25 90.1 7.6 2.3 2 0 0 2 2 2 1 X8 domain Abhydrolase_6 PF12697.7 KZN83398.1 - 2.1e-12 48.1 0.3 3.8e-12 47.3 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family CorA PF01544.18 KZN83399.1 - 5e-12 45.7 3.6 9.7e-12 44.8 3.6 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein ALIX_LYPXL_bnd PF13949.6 KZN83399.1 - 0.038 13.3 2.8 0.055 12.8 2.8 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV DUF948 PF06103.11 KZN83399.1 - 1.6 9.1 5.1 19 5.6 0.0 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) FAD_binding_4 PF01565.23 KZN83400.1 - 3.1e-27 95.0 0.2 6.5e-27 94.0 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain DUF1367 PF07105.11 KZN83401.1 - 0.11 12.1 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1367) Cupin_2 PF07883.11 KZN83402.1 - 1.3e-05 24.8 0.1 2.2e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Cupin domain adh_short PF00106.25 KZN83403.1 - 4.9e-25 88.1 0.0 4.9e-17 62.0 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KZN83403.1 - 3.4e-13 49.7 0.0 3.3e-07 30.1 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN83403.1 - 1.8e-07 31.2 0.2 2.6e-07 30.7 0.2 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KZN83403.1 - 0.0033 16.6 0.0 0.014 14.5 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein TPP_enzyme_C PF02775.21 KZN83403.1 - 0.042 13.6 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Shikimate_DH PF01488.20 KZN83403.1 - 0.11 12.6 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MBOAT_2 PF13813.6 KZN83404.1 - 3.5e-20 72.1 1.6 4.1e-20 71.9 0.2 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family p450 PF00067.22 KZN83405.1 - 1.8e-55 188.5 0.0 2.6e-55 188.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.26 KZN83406.1 - 2.6e-87 292.6 1.1 9.7e-87 290.7 0.3 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KZN83406.1 - 3.2e-62 210.9 1.0 8.5e-62 209.5 1.0 1.8 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KZN83406.1 - 5.2e-61 205.7 0.0 1.8e-59 200.7 0.0 3.0 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 KZN83406.1 - 2.3e-40 137.3 1.2 1e-39 135.2 0.5 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KZN83406.1 - 7.4e-13 48.4 2.4 1e-12 47.9 1.3 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase PP-binding PF00550.25 KZN83406.1 - 2.5e-09 37.4 0.0 6.7e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KZN83406.1 - 7.7e-07 29.6 0.0 6.8e-06 26.5 0.0 2.4 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KZN83406.1 - 4.7e-06 26.2 0.0 0.00021 20.8 0.0 3.3 3 1 0 3 3 3 1 short chain dehydrogenase Thiolase_N PF00108.23 KZN83406.1 - 8.4e-06 25.3 0.3 3.3e-05 23.4 0.1 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Haem_oxygenas_2 PF14518.6 KZN83406.1 - 0.028 14.2 0.1 1.7 8.4 0.0 3.2 3 0 0 3 3 3 0 Iron-containing redox enzyme DUF1442 PF07279.11 KZN83406.1 - 0.051 12.9 0.5 0.23 10.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1442) SAT PF16073.5 KZN83406.1 - 0.17 11.6 1.6 1.3 8.7 0.4 2.7 2 0 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis UbiA PF01040.18 KZN83407.1 - 2.9e-42 144.7 15.4 3.7e-42 144.4 15.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Amidohydro_2 PF04909.14 KZN83408.1 - 3.3e-29 102.6 0.1 9.5e-29 101.1 0.1 1.6 1 1 0 1 1 1 1 Amidohydrolase p450 PF00067.22 KZN83409.1 - 1.9e-80 270.9 0.0 2.5e-80 270.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 S-methyl_trans PF02574.16 KZN83410.1 - 2.6e-28 99.6 0.0 3.1e-28 99.3 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Ala_racemase_N PF01168.20 KZN83410.1 - 0.015 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain Pkinase PF00069.25 KZN83411.1 - 2.8e-13 49.9 0.0 3.6e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN83411.1 - 1.9e-12 47.1 0.0 2.9e-12 46.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KZN83411.1 - 0.00069 19.6 0.5 0.0012 18.8 0.4 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KZN83411.1 - 0.0019 17.6 0.1 0.003 17.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KZN83411.1 - 0.026 14.1 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 ADH_N PF08240.12 KZN83412.1 - 9.1e-22 77.0 7.4 1.5e-21 76.3 7.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN83412.1 - 2.9e-17 62.9 0.0 4.9e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KZN83412.1 - 1.2e-05 26.3 0.0 2.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KZN83412.1 - 5.2e-05 22.6 0.0 9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KZN83412.1 - 0.00039 19.8 0.0 0.00062 19.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ferritin_2 PF13668.6 KZN83413.1 - 7.5e-30 103.9 5.5 1.5e-28 99.7 5.5 2.3 1 1 0 1 1 1 1 Ferritin-like domain MFS_1 PF07690.16 KZN83415.1 - 4.9e-32 111.2 22.5 4.9e-32 111.2 22.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sulfatase PF00884.23 KZN83416.1 - 8.6e-65 219.1 1.4 1.1e-64 218.8 1.4 1.1 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 KZN83416.1 - 0.0011 19.2 0.5 0.0042 17.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 KZN83416.1 - 0.0029 17.2 2.9 0.019 14.6 2.9 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.12 KZN83416.1 - 0.18 10.8 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) APG17 PF04108.12 KZN83417.1 - 0.065 12.3 0.1 0.098 11.7 0.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 DUF1598 PF07643.11 KZN83419.1 - 0.14 12.5 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1598) MFS_1 PF07690.16 KZN83423.1 - 2.4e-46 158.3 43.1 4.8e-46 157.3 43.1 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KZN83423.1 - 1e-11 44.0 10.8 1e-11 44.0 10.8 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KZN83423.1 - 9.9e-11 41.2 12.9 9.9e-11 41.2 12.9 3.0 2 2 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KZN83423.1 - 0.15 10.3 11.0 0.51 8.5 1.4 2.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Glyco_hydro_15 PF00723.21 KZN83424.1 - 8.8e-106 354.4 0.1 1.1e-105 354.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KZN83424.1 - 1.3e-32 111.6 1.2 2.9e-32 110.4 1.2 1.6 1 0 0 1 1 1 1 Starch binding domain Gag_spuma PF03276.14 KZN83424.1 - 0.036 12.5 0.3 0.052 12.0 0.3 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Alpha-amylase PF00128.24 KZN83425.1 - 2.5e-68 231.2 1.0 3.3e-68 230.7 1.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain CBM_20 PF00686.19 KZN83425.1 - 1.8e-32 111.1 0.4 4.2e-32 109.9 0.4 1.7 1 0 0 1 1 1 1 Starch binding domain DUF1966 PF09260.11 KZN83425.1 - 1.2e-31 108.8 0.3 3.2e-31 107.4 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) hDGE_amylase PF14701.6 KZN83425.1 - 0.0046 16.1 0.0 0.0082 15.3 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GHL10 PF02638.15 KZN83425.1 - 0.053 12.6 0.2 0.084 11.9 0.2 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 COesterase PF00135.28 KZN83426.1 - 7.4e-82 275.9 0.0 1e-81 275.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KZN83426.1 - 0.00012 22.0 0.7 0.00071 19.5 0.7 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KZN83426.1 - 0.031 13.7 0.1 0.92 8.9 0.1 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family PTR2 PF00854.21 KZN83427.1 - 7.2e-78 262.1 8.8 9.1e-78 261.8 8.8 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 KZN83427.1 - 2.4e-05 23.4 21.6 2.4e-05 23.4 21.6 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Lipase_3 PF01764.25 KZN83430.1 - 6.6e-29 100.6 0.0 9.3e-29 100.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 KZN83430.1 - 0.00049 20.1 0.0 0.0009 19.2 0.0 1.4 1 0 0 1 1 1 1 Lipase 3 N-terminal region Hydrolase_4 PF12146.8 KZN83430.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 KZN83430.1 - 0.078 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) FMO-like PF00743.19 KZN83431.1 - 1.3e-17 63.4 0.0 1.3e-16 60.1 0.0 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KZN83431.1 - 9.2e-15 54.6 0.0 2e-11 43.7 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KZN83431.1 - 1e-14 54.6 0.0 3.5e-14 52.8 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN83431.1 - 1.7e-10 41.0 0.0 8.9e-08 32.3 0.0 2.8 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KZN83431.1 - 4.8e-08 32.5 0.1 3.4e-06 26.4 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KZN83431.1 - 5e-07 29.2 0.0 1.5e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KZN83431.1 - 1.1e-06 28.5 0.4 0.00088 18.9 0.3 3.8 4 1 0 4 4 4 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KZN83431.1 - 3.1e-05 24.4 0.0 0.011 16.3 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KZN83431.1 - 0.00058 19.0 0.0 0.12 11.4 0.0 3.3 4 0 0 4 4 4 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KZN83431.1 - 0.00092 19.2 0.1 5.5 7.0 0.0 3.8 4 0 0 4 4 4 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KZN83431.1 - 0.0038 16.6 0.1 0.23 10.8 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Mqo PF06039.15 KZN83431.1 - 0.0081 14.8 0.0 0.44 9.1 0.0 2.6 2 1 1 3 3 3 1 Malate:quinone oxidoreductase (Mqo) Shikimate_DH PF01488.20 KZN83431.1 - 0.0093 16.0 0.0 0.16 12.0 0.0 2.8 4 0 0 4 4 4 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KZN83431.1 - 0.016 14.3 0.0 0.076 12.1 0.1 2.1 3 0 0 3 3 3 0 FAD binding domain Amino_oxidase PF01593.24 KZN83431.1 - 0.032 13.5 0.0 7.2 5.8 0.0 2.3 1 1 0 2 2 2 0 Flavin containing amine oxidoreductase GIDA PF01134.22 KZN83431.1 - 0.034 13.2 0.9 0.88 8.6 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 KZN83431.1 - 0.047 14.1 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding HI0933_like PF03486.14 KZN83431.1 - 0.23 10.1 0.1 1.6 7.3 0.1 2.3 3 0 0 3 3 3 0 HI0933-like protein Abhydrolase_3 PF07859.13 KZN83432.1 - 3.8e-21 75.9 0.0 5.6e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KZN83432.1 - 1e-12 47.7 0.0 2e-12 46.7 0.0 1.4 1 1 0 1 1 1 1 Steryl acetyl hydrolase adh_short PF00106.25 KZN83433.1 - 3.3e-39 134.4 0.2 5.7e-39 133.6 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN83433.1 - 2.1e-27 96.2 0.0 3.2e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN83433.1 - 3.2e-06 27.2 1.4 8.6e-05 22.5 1.4 2.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KZN83433.1 - 0.0002 20.9 0.1 0.0003 20.3 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family UPF0146 PF03686.13 KZN83433.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) p450 PF00067.22 KZN83434.1 - 1.8e-75 254.5 0.0 2.3e-75 254.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KZN83435.1 - 9.3e-32 110.3 25.3 9.3e-32 110.3 25.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN83435.1 - 6.4e-10 38.5 5.5 6.4e-10 38.5 5.5 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KZN83435.1 - 2.1e-07 29.8 3.4 2.1e-07 29.8 3.4 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_28 PF00295.17 KZN83436.1 - 5.9e-55 186.6 3.3 8.3e-55 186.1 3.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF4528 PF15031.6 KZN83436.1 - 0.014 15.4 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4528) MAPEG PF01124.18 KZN83437.1 - 9.4e-15 54.7 1.5 1.3e-14 54.2 1.5 1.2 1 0 0 1 1 1 1 MAPEG family Pyridoxal_deC PF00282.19 KZN83438.1 - 3.7e-73 246.4 0.0 4.8e-73 246.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain GST_C_6 PF17171.4 KZN83438.1 - 0.17 11.7 0.0 0.93 9.3 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Fungal_trans PF04082.18 KZN83439.1 - 5.8e-20 71.4 0.1 1.1e-19 70.5 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN83439.1 - 3.4e-07 30.3 9.0 8.3e-07 29.0 9.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC2_membrane PF01061.24 KZN83440.1 - 8.3e-71 237.7 50.3 7.1e-38 130.1 25.7 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KZN83440.1 - 3e-37 128.2 0.0 3.3e-17 63.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KZN83440.1 - 3e-23 81.5 0.2 3e-23 81.5 0.2 3.4 4 0 0 4 4 2 2 CDR ABC transporter AAA_16 PF13191.6 KZN83440.1 - 1.5e-06 28.7 0.5 0.00021 21.7 0.2 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KZN83440.1 - 4.4e-06 26.7 0.1 0.008 16.0 0.1 2.7 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KZN83440.1 - 1.1e-05 24.7 35.4 0.00047 19.4 15.6 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KZN83440.1 - 3.3e-05 23.9 0.1 0.0031 17.4 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KZN83440.1 - 5.5e-05 22.8 0.5 0.0063 16.2 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KZN83440.1 - 0.0001 22.3 0.0 0.037 14.1 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.6 KZN83440.1 - 0.00021 20.9 0.5 0.026 14.1 0.1 2.9 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KZN83440.1 - 0.0013 19.0 0.1 0.15 12.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KZN83440.1 - 0.0034 17.5 0.0 0.28 11.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KZN83440.1 - 0.0045 16.7 0.4 1.2 8.8 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KZN83440.1 - 0.013 16.0 0.1 0.092 13.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KZN83440.1 - 0.029 14.9 0.1 0.073 13.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KZN83440.1 - 0.041 13.2 0.0 11 5.3 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.6 KZN83440.1 - 0.05 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KZN83440.1 - 0.059 13.3 0.3 2.4 8.0 0.0 2.7 3 0 0 3 3 2 0 NACHT domain SMC_N PF02463.19 KZN83440.1 - 0.097 12.1 0.0 13 5.1 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 KZN83440.1 - 0.19 11.0 1.5 5 6.3 0.4 2.8 3 0 0 3 3 3 0 Zeta toxin Ploopntkinase3 PF18751.1 KZN83440.1 - 0.26 11.2 0.6 1.5 8.7 0.1 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 ABC2_membrane_2 PF12679.7 KZN83440.1 - 0.26 10.5 20.5 0.074 12.3 9.6 2.4 2 0 0 2 2 2 0 ABC-2 family transporter protein Mannosyl_trans3 PF11051.8 KZN83442.1 - 0.039 13.3 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Glyco_transf_8 PF01501.20 KZN83442.1 - 0.12 11.9 1.7 0.27 10.7 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 8 Methyltransf_2 PF00891.18 KZN83444.1 - 3e-12 46.3 0.0 6.3e-12 45.2 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 KZN83444.1 - 0.0079 16.1 0.0 0.017 14.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Dimerisation PF08100.11 KZN83444.1 - 0.058 13.4 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain MFS_1 PF07690.16 KZN83445.1 - 6.7e-24 84.5 46.3 6.7e-24 84.5 46.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fringe PF02434.16 KZN83446.1 - 7.6e-05 22.3 2.0 0.002 17.6 0.2 3.1 3 1 0 3 3 3 1 Fringe-like PAN_1 PF00024.26 KZN83446.1 - 9.8e-05 22.2 0.2 0.0002 21.3 0.2 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 KZN83446.1 - 0.0069 16.3 0.4 0.014 15.2 0.4 1.5 1 0 0 1 1 1 1 PAN domain DUF2235 PF09994.9 KZN83447.1 - 6e-76 255.5 0.0 7.4e-76 255.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Pkinase PF00069.25 KZN83449.1 - 4.4e-43 147.6 0.0 6.1e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN83449.1 - 8e-25 87.6 0.0 1.2e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_12 PF13424.6 KZN83449.1 - 1.1e-22 80.1 9.8 5.6e-09 36.2 1.0 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 KZN83449.1 - 3.3e-22 77.7 13.4 4.9e-07 29.4 0.1 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 KZN83449.1 - 2.4e-11 42.8 9.7 0.031 14.4 0.1 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KZN83449.1 - 5.3e-09 36.2 5.2 0.0016 18.6 0.1 3.4 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KZN83449.1 - 1.3e-07 31.2 1.4 0.25 11.2 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.12 KZN83449.1 - 1.5e-06 28.0 3.2 2.5 8.2 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KZN83449.1 - 3.4e-06 27.6 6.3 0.022 15.4 0.5 4.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KZN83449.1 - 0.00018 21.5 2.7 14 6.2 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KZN83449.1 - 0.0015 19.2 2.5 15 6.7 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Kdo PF06293.14 KZN83449.1 - 0.0053 16.1 0.0 0.0096 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_6 PF13174.6 KZN83449.1 - 0.0063 17.1 7.6 0.45 11.3 0.5 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Haspin_kinase PF12330.8 KZN83449.1 - 0.15 11.0 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain TPR_7 PF13176.6 KZN83449.1 - 0.84 9.8 6.0 53 4.2 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.16 KZN83450.1 - 1.5e-17 63.5 58.0 6.6e-10 38.4 28.0 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily PUCC PF03209.15 KZN83450.1 - 3.3e-05 23.1 11.9 3.3e-05 23.1 11.9 2.6 3 2 1 3 3 3 1 PUCC protein zf-HC3 PF16827.5 KZN83450.1 - 0.071 13.3 0.3 0.16 12.2 0.3 1.5 1 0 0 1 1 1 0 zinc-finger Fungal_trans PF04082.18 KZN83451.1 - 6.5e-20 71.3 0.0 2.1e-19 69.6 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN83451.1 - 3.8e-07 30.1 14.2 6.1e-07 29.5 14.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ysc84 PF04366.12 KZN83452.1 - 4.8e-46 155.7 0.1 6.9e-46 155.2 0.1 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator DHquinase_I PF01487.15 KZN83454.1 - 9.3e-34 117.7 0.0 1.5e-33 117.0 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KZN83454.1 - 3.4e-19 69.5 0.6 2e-18 67.0 0.0 2.3 3 0 0 3 3 3 1 Shikimate kinase Shikimate_dh_N PF08501.11 KZN83454.1 - 8.4e-14 51.6 0.0 2.1e-13 50.3 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 KZN83454.1 - 5.5e-09 36.2 0.0 1.3e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 KZN83454.1 - 1.5e-05 24.7 0.0 3.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain F420_oxidored PF03807.17 KZN83454.1 - 0.013 16.1 0.0 0.033 14.8 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent zf-piccolo PF05715.13 KZN83455.1 - 5.5 7.2 9.3 12 6.2 0.1 2.7 2 0 0 2 2 2 0 Piccolo Zn-finger Sec10 PF07393.11 KZN83457.1 - 1.5e-230 767.4 0.0 1.8e-230 767.2 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 Tropomyosin PF00261.20 KZN83457.1 - 0.042 13.2 0.1 0.12 11.8 0.1 1.7 1 0 0 1 1 1 0 Tropomyosin Phage_min_cap2 PF06152.11 KZN83457.1 - 0.14 11.0 0.1 13 4.6 0.0 2.2 2 0 0 2 2 2 0 Phage minor capsid protein 2 Baculo_PEP_C PF04513.12 KZN83457.1 - 0.43 10.6 5.8 1.9 8.5 0.6 3.3 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 KZN83457.1 - 6.9 6.5 9.0 6.6 6.6 1.0 3.3 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain Glyco_tranf_2_3 PF13641.6 KZN83458.1 - 7.1e-25 88.2 0.0 1.1e-24 87.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KZN83458.1 - 2.7e-10 40.5 0.6 2.7e-10 40.5 0.6 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KZN83458.1 - 0.0066 16.3 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KZN83458.1 - 0.0078 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Sortilin-Vps10 PF15902.5 KZN83460.1 - 4.8e-277 918.8 5.8 5.9e-141 470.3 1.8 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KZN83460.1 - 9e-92 306.0 14.1 1.2e-46 159.2 1.2 2.9 3 0 0 3 3 3 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 KZN83460.1 - 1.2e-07 30.6 30.7 2.7 8.3 0.3 10.9 11 0 0 11 11 11 5 BNR/Asp-box repeat DUF2167 PF09935.9 KZN83460.1 - 0.01 15.0 0.2 0.026 13.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2167) BNR_2 PF13088.6 KZN83460.1 - 0.014 14.7 0.9 46 3.2 0.0 4.8 5 0 0 5 5 5 0 BNR repeat-like domain dCMP_cyt_deam_1 PF00383.23 KZN83461.1 - 2.9e-15 56.0 0.2 3.5e-15 55.7 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KZN83461.1 - 2.5e-08 34.2 1.5 1.3e-06 28.6 0.2 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 KZN83461.1 - 1.3e-05 24.9 0.6 0.085 12.5 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases NmrA PF05368.13 KZN83462.1 - 1.2e-33 116.6 0.0 1.8e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Peptidase_C12 PF01088.21 KZN83462.1 - 4.8e-32 111.4 0.0 7.8e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 NAD_binding_10 PF13460.6 KZN83462.1 - 1.3e-12 48.0 0.0 1.9e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Fungal_trans PF04082.18 KZN83463.1 - 1.2e-15 57.3 0.0 1.9e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN83463.1 - 0.017 15.3 4.9 0.032 14.4 4.9 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.27 KZN83464.1 - 2.3e-64 213.3 0.4 9.2e-21 73.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cgr1 PF03879.14 KZN83465.1 - 1.5e-33 115.4 25.0 1.7e-33 115.2 25.0 1.0 1 0 0 1 1 1 1 Cgr1 family DUF4192 PF13830.6 KZN83465.1 - 0.34 10.9 3.1 0.33 11.0 3.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) GAS PF13851.6 KZN83466.1 - 0.00019 20.8 2.6 0.00036 19.9 2.6 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 KZN83466.1 - 0.0026 16.7 1.6 0.004 16.1 1.6 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_13 PF13166.6 KZN83466.1 - 0.011 14.4 1.0 0.017 13.8 1.0 1.2 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.12 KZN83466.1 - 0.016 15.3 1.5 0.13 12.3 1.5 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus MCU PF04678.13 KZN83466.1 - 0.037 14.1 0.8 0.09 12.9 0.7 1.7 1 1 0 1 1 1 0 Mitochondrial calcium uniporter CbtA PF09490.10 KZN83466.1 - 0.062 13.1 0.0 0.096 12.4 0.0 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Snapin_Pallidin PF14712.6 KZN83466.1 - 0.069 13.6 1.4 0.17 12.3 1.4 1.7 1 0 0 1 1 1 0 Snapin/Pallidin HsbA PF12296.8 KZN83466.1 - 0.072 13.5 0.7 1.8 9.0 0.4 2.7 2 1 0 2 2 2 0 Hydrophobic surface binding protein A DUF1664 PF07889.12 KZN83466.1 - 0.12 12.4 0.3 1.3 9.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3552 PF12072.8 KZN83466.1 - 0.13 11.6 3.2 0.27 10.6 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) JIP_LZII PF16471.5 KZN83466.1 - 0.16 12.2 2.8 1.2 9.3 1.0 2.5 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II EMP24_GP25L PF01105.24 KZN83466.1 - 0.17 11.8 0.5 0.29 11.0 0.5 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Csm1_N PF18504.1 KZN83466.1 - 0.21 11.9 2.5 4.5 7.7 0.5 2.6 1 1 1 2 2 2 0 Csm1 N-terminal domain FUSC PF04632.12 KZN83466.1 - 0.23 10.0 0.7 0.36 9.3 0.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Occludin_ELL PF07303.13 KZN83466.1 - 0.73 10.6 5.1 0.35 11.6 0.6 2.6 2 1 0 2 2 2 0 Occludin homology domain SUI1 PF01253.22 KZN83467.1 - 4.4e-22 78.4 0.2 8.1e-22 77.5 0.2 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.6 KZN83467.1 - 0.041 13.9 0.1 0.067 13.2 0.1 1.3 1 0 0 1 1 1 0 Transposon-encoded protein TnpV DUF1752 PF08550.10 KZN83468.1 - 6.6e-12 45.0 5.6 1.3e-11 44.1 5.6 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) ELMO_CED12 PF04727.13 KZN83469.1 - 9.7e-49 165.9 0.0 1.6e-48 165.1 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 KZN83469.1 - 1.1e-29 103.6 0.0 3.2e-29 102.1 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 KZN83469.1 - 3.9e-15 56.1 0.0 9.1e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) Rad17 PF03215.15 KZN83470.1 - 1.8e-27 96.5 0.0 2.9e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KZN83470.1 - 8.7e-06 26.2 0.0 2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KZN83470.1 - 0.00078 19.9 0.0 0.0024 18.3 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KZN83470.1 - 0.0071 16.6 0.0 0.018 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KZN83470.1 - 0.012 15.4 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KZN83470.1 - 0.025 15.1 0.0 0.069 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KZN83470.1 - 0.064 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 KZN83470.1 - 0.09 12.9 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 KZN83470.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase TsaE PF02367.17 KZN83470.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE UAA PF08449.11 KZN83471.1 - 6.9e-87 291.5 8.9 1.7e-86 290.1 8.9 1.5 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KZN83471.1 - 6.7e-05 22.2 0.5 6.7e-05 22.2 0.5 1.8 2 0 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.20 KZN83471.1 - 0.082 13.1 27.4 0.088 13.0 7.8 3.6 2 2 1 3 3 3 0 EamA-like transporter family Dynamin_M PF01031.20 KZN83472.1 - 1e-110 369.5 0.0 1.6e-110 368.8 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KZN83472.1 - 1.7e-54 184.4 0.0 3.2e-54 183.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KZN83472.1 - 1.6e-31 108.3 0.6 1.6e-31 108.3 0.6 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KZN83472.1 - 0.00023 21.2 0.2 0.002 18.2 0.2 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KZN83472.1 - 0.026 14.1 0.1 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B SH3_9 PF14604.6 KZN83473.1 - 4.4e-26 90.5 6.3 6.7e-13 48.3 0.9 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KZN83473.1 - 1.5e-24 85.3 5.8 1.8e-12 46.7 0.6 2.4 2 0 0 2 2 2 2 SH3 domain Cofilin_ADF PF00241.20 KZN83473.1 - 2.6e-15 56.3 0.0 5e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 KZN83473.1 - 6.1e-15 54.6 0.5 2e-06 27.4 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain A_deaminase PF00962.22 KZN83474.1 - 5.4e-124 413.8 0.0 8e-124 413.2 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF3752 PF12572.8 KZN83476.1 - 4.5e-40 137.6 13.8 5.4e-40 137.4 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) Dynamitin PF04912.14 KZN83476.1 - 0.0078 15.6 2.0 0.009 15.4 2.0 1.0 1 0 0 1 1 1 1 Dynamitin Metallophos PF00149.28 KZN83477.1 - 4.1e-09 37.2 0.1 1.4e-08 35.5 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KZN83477.1 - 5.2e-07 30.0 0.2 3.7e-05 24.0 0.2 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain F-box PF00646.33 KZN83478.1 - 1.7e-05 24.5 0.1 4.3e-05 23.3 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KZN83478.1 - 0.00012 21.9 0.2 0.00028 20.7 0.2 1.6 1 0 0 1 1 1 1 F-box-like ALAD PF00490.21 KZN83479.1 - 1.1e-121 405.9 0.0 1.4e-121 405.6 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Mac_assoc PF16628.5 KZN83480.1 - 1.1e-78 263.7 9.1 1.1e-78 263.7 9.1 2.2 2 1 0 2 2 2 1 Unstructured region on maltose acetyltransferase Mac PF12464.8 KZN83480.1 - 3.5e-11 43.2 0.0 7.6e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Zn_clus PF00172.18 KZN83480.1 - 1.1e-09 38.2 8.4 2.1e-09 37.3 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep PF00132.24 KZN83480.1 - 9.8e-09 34.6 6.1 0.0001 21.9 0.3 3.5 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KZN83480.1 - 4.7e-05 23.0 1.4 4.7e-05 23.0 1.4 3.4 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase CRM1_C PF08767.11 KZN83481.1 - 7.2e-137 455.8 4.8 7.2e-137 455.8 4.8 2.9 2 1 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 KZN83481.1 - 7.9e-43 146.1 4.5 7.9e-43 146.1 4.5 4.0 5 0 0 5 5 5 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KZN83481.1 - 2.6e-33 113.5 4.8 1.1e-32 111.5 4.7 2.3 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KZN83481.1 - 9.4e-29 99.3 0.6 9.4e-29 99.3 0.6 2.8 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KZN83481.1 - 4.3e-19 67.7 0.8 1e-18 66.5 0.8 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KZN83481.1 - 1.2e-11 44.4 0.1 5.5e-11 42.2 0.1 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 KZN83481.1 - 0.0028 17.6 1.7 0.11 12.5 0.0 4.1 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) Hemocyanin_M PF00372.19 KZN83481.1 - 0.042 13.0 0.2 0.21 10.7 0.1 2.1 2 0 0 2 2 2 0 Hemocyanin, copper containing domain DRE2_N PF16803.5 KZN83481.1 - 0.12 12.6 0.4 0.83 9.9 0.0 2.6 3 0 0 3 3 3 0 Fe-S cluster assembly protein DRE2 N-terminus PPI_Ypi1 PF07491.11 KZN83482.1 - 4.5e-25 87.2 8.7 2.1e-24 85.1 8.7 2.2 1 1 0 1 1 1 1 Protein phosphatase inhibitor CDC45 PF02724.14 KZN83482.1 - 0.33 9.2 8.4 0.35 9.1 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Shugoshin_N PF07558.11 KZN83483.1 - 6.5e-19 67.5 5.0 2.1e-18 65.9 5.0 2.0 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 KZN83483.1 - 2.6e-11 43.1 5.0 2.6e-11 43.1 5.0 2.4 2 0 0 2 2 2 1 Shugoshin C terminus bZIP_1 PF00170.21 KZN83483.1 - 0.036 14.2 1.4 0.17 12.0 1.4 2.3 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 KZN83483.1 - 0.079 13.1 0.3 0.079 13.1 0.3 2.3 2 0 0 2 2 2 0 Basic region leucine zipper DASH_Dad2 PF08654.10 KZN83484.1 - 7.6e-30 103.3 0.1 9.9e-30 102.9 0.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 Seryl_tRNA_N PF02403.22 KZN83484.1 - 0.032 14.5 0.2 0.048 13.9 0.2 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DASH_Duo1 PF08651.10 KZN83484.1 - 0.12 12.2 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 DASH complex subunit Duo1 p450 PF00067.22 KZN83485.1 - 3.5e-71 240.3 0.0 4e-71 240.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RBD-FIP PF09457.10 KZN83485.1 - 0.065 13.2 0.2 0.12 12.3 0.2 1.3 1 0 0 1 1 1 0 FIP domain DAO PF01266.24 KZN83486.1 - 8.6e-52 176.9 0.0 1.2e-51 176.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KZN83486.1 - 5e-43 146.0 0.0 9.2e-43 145.1 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KZN83486.1 - 5.5e-09 35.6 0.6 1.3e-08 34.3 0.6 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KZN83486.1 - 0.00064 19.0 0.1 0.0019 17.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN83486.1 - 0.00092 19.4 0.1 0.0048 17.1 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KZN83486.1 - 0.0016 17.8 0.6 0.0048 16.3 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KZN83486.1 - 0.0063 16.4 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KZN83486.1 - 0.013 14.8 0.0 0.041 13.1 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KZN83486.1 - 0.018 14.3 0.0 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 KZN83486.1 - 0.021 14.1 0.1 0.045 13.0 0.1 1.6 1 1 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KZN83486.1 - 0.028 13.1 0.2 0.049 12.3 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KZN83486.1 - 0.11 13.0 0.1 0.33 11.5 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KZN83486.1 - 0.12 11.4 0.1 0.73 8.8 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A NFACT-R_1 PF05670.13 KZN83488.1 - 3.3e-36 124.3 0.1 2.1e-35 121.6 0.1 2.1 1 1 0 1 1 1 1 NFACT protein RNA binding domain TBCC PF07986.12 KZN83488.1 - 0.0049 16.6 0.1 0.072 12.8 0.0 2.4 2 1 0 2 2 2 1 Tubulin binding cofactor C Pox_P35 PF03213.14 KZN83488.1 - 1.6 7.9 9.4 1.6 7.9 0.1 2.1 1 1 1 2 2 2 0 Poxvirus P35 protein Paramyxo_ncap PF00973.19 KZN83488.1 - 2 7.3 6.7 2.5 6.9 6.7 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Mrx7 PF10906.8 KZN83488.1 - 8.2 6.8 13.4 1.4e+03 -0.4 13.4 2.5 1 1 0 1 1 1 0 MIOREX complex component 7 GRAB PF10375.9 KZN83489.1 - 1.1e-08 34.6 0.1 2.4e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Golgin_A5 PF09787.9 KZN83489.1 - 0.00082 18.9 57.1 0.014 14.8 18.1 3.2 1 1 2 3 3 3 2 Golgin subfamily A member 5 Spc7 PF08317.11 KZN83489.1 - 0.0014 17.6 55.9 0.023 13.6 31.9 2.3 1 1 1 2 2 2 2 Spc7 kinetochore protein Fib_alpha PF08702.10 KZN83489.1 - 0.014 15.5 33.3 0.019 15.1 4.3 3.8 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family BST2 PF16716.5 KZN83489.1 - 0.038 14.6 44.7 0.23 12.1 9.2 5.4 2 2 3 5 5 5 0 Bone marrow stromal antigen 2 Baculo_PEP_C PF04513.12 KZN83489.1 - 0.078 13.0 20.9 0.49 10.4 4.5 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.21 KZN83489.1 - 0.098 12.2 52.8 0.097 12.2 19.5 3.1 1 1 2 3 3 3 0 Intermediate filament protein TPR_MLP1_2 PF07926.12 KZN83489.1 - 0.1 12.7 62.0 0.031 14.3 5.3 4.9 1 1 5 6 6 6 0 TPR/MLP1/MLP2-like protein APC_N_CC PF16689.5 KZN83489.1 - 0.22 11.6 14.6 0.38 10.9 5.4 3.7 3 0 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain GAS PF13851.6 KZN83489.1 - 3.9 6.8 58.4 0.19 11.1 8.8 3.9 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 KZN83489.1 - 4.8 7.2 36.5 0.2 11.7 5.5 4.3 1 1 3 4 4 4 0 Laminin Domain II DUF1664 PF07889.12 KZN83489.1 - 8 6.5 30.8 0.49 10.4 5.7 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) HMMR_N PF15905.5 KZN83489.1 - 8.7 5.7 58.9 1.7 8.1 18.5 2.8 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal FAM184 PF15665.5 KZN83489.1 - 9.3 6.0 54.6 1.5 8.5 16.8 3.3 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B IFT57 PF10498.9 KZN83489.1 - 9.7 5.0 43.2 0.25 10.3 15.2 2.4 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Guanylate_kin PF00625.21 KZN83490.1 - 1.3e-64 217.2 0.0 1.6e-64 216.9 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 KZN83490.1 - 1.4e-06 28.8 0.3 6.2e-06 26.7 0.3 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KZN83490.1 - 2.3e-05 25.0 0.1 7.1e-05 23.4 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KZN83490.1 - 2.3e-05 24.6 0.2 0.00026 21.2 0.2 2.4 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KZN83490.1 - 9.7e-05 22.9 0.0 0.00023 21.7 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 KZN83490.1 - 0.00013 22.2 0.0 0.00032 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KZN83490.1 - 0.00016 21.9 0.1 0.0013 19.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KZN83490.1 - 0.0013 18.5 0.0 0.047 13.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KZN83490.1 - 0.0017 17.9 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KZN83490.1 - 0.0042 17.0 0.0 0.008 16.1 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 KZN83490.1 - 0.0043 17.0 0.0 0.0059 16.5 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain MMR_HSR1 PF01926.23 KZN83490.1 - 0.0044 17.1 0.0 0.0084 16.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase T2SSE PF00437.20 KZN83490.1 - 0.005 15.9 0.0 0.0097 15.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein RNA_helicase PF00910.22 KZN83490.1 - 0.0058 17.0 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase DUF2075 PF09848.9 KZN83490.1 - 0.0069 15.7 0.0 0.054 12.7 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 KZN83490.1 - 0.0074 16.3 0.0 0.016 15.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_29 PF13555.6 KZN83490.1 - 0.0099 15.6 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain NTPase_1 PF03266.15 KZN83490.1 - 0.013 15.5 0.0 0.017 15.0 0.0 1.5 1 1 0 1 1 1 0 NTPase NACHT PF05729.12 KZN83490.1 - 0.014 15.3 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 KZN83490.1 - 0.015 15.0 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 KZN83490.1 - 0.023 13.5 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA PF00004.29 KZN83490.1 - 0.025 15.0 0.1 0.047 14.1 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KZN83490.1 - 0.039 13.8 0.1 0.049 13.5 0.1 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea dNK PF01712.19 KZN83490.1 - 0.044 13.6 0.3 0.48 10.2 0.0 2.3 2 1 1 3 3 3 0 Deoxynucleoside kinase AAA_5 PF07728.14 KZN83490.1 - 0.047 13.7 0.1 0.32 11.0 0.0 2.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 KZN83490.1 - 0.06 13.8 0.1 0.62 10.5 0.1 2.3 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 KZN83490.1 - 0.077 12.6 0.0 0.21 11.1 0.0 1.6 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Sigma54_activat PF00158.26 KZN83490.1 - 0.099 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.6 KZN83490.1 - 0.11 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KZN83490.1 - 0.16 11.7 0.3 0.3 10.8 0.0 1.6 2 0 0 2 2 2 0 Cytidylate kinase AAA_23 PF13476.6 KZN83490.1 - 0.16 12.5 1.7 0.28 11.6 0.0 1.9 2 1 0 2 2 2 0 AAA domain T3SS_needle_E PF08988.10 KZN83490.1 - 0.17 12.0 1.3 0.34 11.1 1.3 1.5 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle Septin PF00735.18 KZN83491.1 - 2.8e-113 377.9 0.7 3.3e-113 377.6 0.7 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KZN83491.1 - 2.1e-08 34.2 0.0 5.2e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KZN83491.1 - 1.5e-05 24.5 0.0 2.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KZN83491.1 - 4.9e-05 23.3 0.4 0.00049 20.0 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KZN83491.1 - 8e-05 22.3 0.6 0.015 14.9 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KZN83491.1 - 0.00028 21.0 0.4 0.99 9.4 0.1 2.6 1 1 1 2 2 2 2 Dynamin family AAA_7 PF12775.7 KZN83491.1 - 0.0027 17.2 0.1 0.02 14.4 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Gtr1_RagA PF04670.12 KZN83491.1 - 0.0037 16.6 0.3 0.095 12.0 0.3 2.2 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KZN83491.1 - 0.0042 17.5 0.1 0.014 15.7 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KZN83491.1 - 0.0053 16.0 0.1 0.0097 15.1 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.27 KZN83491.1 - 0.0097 16.4 0.6 0.016 15.7 0.4 1.7 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 KZN83491.1 - 0.012 15.9 0.1 0.027 14.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 KZN83491.1 - 0.055 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 KZN83491.1 - 0.062 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family G-alpha PF00503.20 KZN83491.1 - 0.07 12.3 1.0 0.27 10.3 1.0 2.0 1 1 0 1 1 1 0 G-protein alpha subunit AAA_23 PF13476.6 KZN83491.1 - 0.14 12.7 0.5 0.32 11.5 0.5 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KZN83491.1 - 0.16 11.8 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_L32p PF01783.23 KZN83492.1 - 6.2e-14 52.0 5.5 8.2e-14 51.6 5.5 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family zf-ribbon_3 PF13248.6 KZN83492.1 - 0.045 13.2 1.9 0.072 12.5 1.9 1.4 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 KZN83492.1 - 0.091 12.8 1.4 0.28 11.2 1.4 1.7 1 1 0 1 1 1 0 Double zinc ribbon WD40 PF00400.32 KZN83493.1 - 1.4e-19 70.0 15.3 8.2e-07 29.6 0.6 6.4 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN83493.1 - 3.8e-14 52.7 1.2 0.00011 22.4 0.4 5.0 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KZN83493.1 - 0.00017 21.5 0.0 0.011 15.7 0.0 2.3 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KZN83493.1 - 0.00063 18.5 0.2 0.0084 14.8 0.1 2.3 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Lactonase PF10282.9 KZN83493.1 - 0.0011 18.4 0.0 0.011 15.1 0.0 2.0 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.16 KZN83493.1 - 0.0012 17.5 0.1 1 7.8 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.12 KZN83493.1 - 0.069 13.1 2.4 22 5.1 0.0 4.1 5 1 1 6 6 6 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KZN83493.1 - 0.097 12.0 0.0 8.7 5.6 0.0 2.6 3 0 0 3 3 3 0 WD40-like domain FG-GAP_2 PF14312.6 KZN83493.1 - 0.1 12.9 0.4 1.3 9.3 0.0 2.6 2 1 0 2 2 2 0 FG-GAP repeat Hira PF07569.11 KZN83493.1 - 0.11 12.2 0.1 7 6.3 0.0 2.3 2 0 0 2 2 2 0 TUP1-like enhancer of split Ge1_WD40 PF16529.5 KZN83493.1 - 0.24 10.3 2.7 28 3.6 0.0 3.8 3 1 2 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Spindle_Spc25 PF08234.12 KZN83494.1 - 3.5e-22 78.4 0.0 8.5e-22 77.1 0.0 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Filament PF00038.21 KZN83494.1 - 0.0015 18.2 12.3 0.0023 17.6 12.3 1.2 1 0 0 1 1 1 1 Intermediate filament protein DUF4140 PF13600.6 KZN83494.1 - 5.2 7.6 8.4 10 6.6 8.4 1.6 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Rrn6 PF10214.9 KZN83495.1 - 1.1e-209 699.1 2.4 1.2e-209 698.9 2.4 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor HMA PF00403.26 KZN83496.1 - 2.7e-17 62.9 0.7 3.3e-17 62.7 0.7 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF211 PF02680.14 KZN83496.1 - 0.018 15.2 0.1 0.023 14.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 Fer2_BFD PF04324.15 KZN83496.1 - 0.089 13.2 0.1 0.23 11.9 0.1 1.7 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain DUF2293 PF10056.9 KZN83497.1 - 4.3e-30 103.8 0.2 1.2e-29 102.3 0.2 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) zinc_ribbon_6 PF14599.6 KZN83498.1 - 9.5e-25 86.4 0.4 9.5e-25 86.4 0.4 3.5 3 1 1 4 4 4 1 Zinc-ribbon zf-CHY PF05495.12 KZN83498.1 - 5.6e-20 71.6 23.5 5.6e-20 71.6 23.5 3.6 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 KZN83498.1 - 2e-08 34.4 8.3 2e-08 34.4 8.3 5.2 2 1 3 5 5 5 1 Ring finger domain zf-RING_UBOX PF13445.6 KZN83498.1 - 1.6e-06 28.1 5.4 1.6e-06 28.1 5.4 3.5 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KZN83498.1 - 1.1e-05 25.1 5.8 1.1e-05 25.1 5.8 4.9 3 1 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KZN83498.1 - 4.4e-05 23.3 7.2 4.4e-05 23.3 7.2 5.9 3 2 3 6 6 6 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KZN83498.1 - 0.013 15.3 8.7 0.013 15.3 8.7 5.9 4 2 1 5 5 5 0 Prokaryotic RING finger family 4 DNA_pol_phi PF04931.13 KZN83498.1 - 5.4 5.0 12.1 7.6 4.5 12.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Tcp11 PF05794.13 KZN83499.1 - 1.3e-111 373.8 0.0 1.3e-111 373.8 0.0 2.7 3 1 0 3 3 3 1 T-complex protein 11 LicD PF04991.13 KZN83499.1 - 0.039 14.1 0.5 0.081 13.1 0.5 1.4 1 0 0 1 1 1 0 LicD family IQ PF00612.27 KZN83499.1 - 0.11 12.3 0.4 0.39 10.6 0.4 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif WD40 PF00400.32 KZN83500.1 - 9.4e-30 102.2 18.4 9.7e-07 29.4 0.1 8.1 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN83500.1 - 1.2e-11 44.8 1.3 0.058 13.7 0.0 4.9 3 2 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KZN83500.1 - 0.13 11.3 0.4 0.97 8.4 0.1 2.0 2 0 0 2 2 2 0 Coatomer WD associated region Peptidase_S10 PF00450.22 KZN83501.1 - 5.6e-113 378.5 0.0 6.8e-113 378.2 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase RNA_Me_trans PF04252.13 KZN83502.1 - 3.2e-83 278.2 0.0 3.5e-83 278.1 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase bPH_5 PF10882.8 KZN83502.1 - 0.027 14.5 0.0 2.4 8.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial PH domain Endosulfine PF04667.17 KZN83503.1 - 7e-29 99.8 0.0 1.1e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region ICE2 PF08426.10 KZN83504.1 - 7.7e-151 502.8 10.5 8.7e-151 502.6 10.5 1.0 1 0 0 1 1 1 1 ICE2 MHYT PF03707.16 KZN83504.1 - 1.1 9.5 0.0 1.1 9.5 0.0 4.5 4 1 0 4 4 4 0 Bacterial signalling protein N terminal repeat UPF0160 PF03690.13 KZN83505.1 - 6.7e-127 423.5 0.0 7.7e-127 423.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Yae1_N PF09811.9 KZN83506.1 - 2.5e-08 33.5 2.7 3.7e-08 32.9 2.7 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal tRNA-synt_1g PF09334.11 KZN83507.1 - 5.7e-146 486.3 0.0 7e-146 486.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KZN83507.1 - 4.1e-07 28.6 0.2 5.1e-05 21.7 0.0 3.4 2 2 1 3 3 3 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KZN83507.1 - 0.013 15.5 0.1 0.026 14.5 0.1 1.5 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA Elongin_A PF06881.11 KZN83507.1 - 1.2 9.7 4.9 4 8.0 4.9 1.9 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A WD40 PF00400.32 KZN83508.1 - 1.7e-17 63.4 2.4 0.011 16.5 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN83508.1 - 1.4e-08 34.9 0.0 0.0022 18.3 0.0 5.1 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KZN83508.1 - 0.0013 18.1 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 WD40-like domain Ge1_WD40 PF16529.5 KZN83508.1 - 0.0033 16.5 0.0 0.087 11.8 0.0 2.8 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein FliO PF04347.13 KZN83508.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Flagellar biosynthesis protein, FliO F-box-like PF12937.7 KZN83511.1 - 0.18 11.7 1.5 0.24 11.3 0.4 1.7 2 0 0 2 2 2 0 F-box-like PXA PF02194.15 KZN83512.1 - 2.1e-50 171.2 0.9 2.1e-50 171.2 0.9 2.7 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.12 KZN83512.1 - 2.6e-26 92.4 0.0 1.6e-25 89.9 0.0 2.5 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.24 KZN83512.1 - 1.6e-21 76.4 0.5 3.4e-21 75.3 0.5 1.6 1 0 0 1 1 1 1 PX domain RGS PF00615.19 KZN83512.1 - 3.7e-11 43.3 0.0 1.3e-10 41.6 0.0 2.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain RRP36 PF06102.12 KZN83512.1 - 0.75 9.7 6.9 0.74 9.8 0.3 2.8 3 0 0 3 3 3 0 rRNA biogenesis protein RRP36 PEMT PF04191.13 KZN83513.1 - 2.2e-33 114.8 2.4 2.2e-33 114.8 2.4 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase YrhK PF14145.6 KZN83513.1 - 0.0047 16.8 2.3 0.019 14.8 2.2 2.3 1 1 0 1 1 1 1 YrhK-like protein DUF1223 PF06764.11 KZN83513.1 - 0.014 15.5 0.0 0.018 15.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) RXT2_N PF08595.11 KZN83514.1 - 4.5e-41 140.5 0.0 4.5e-41 140.5 0.0 2.7 2 1 0 2 2 2 1 RXT2-like, N-terminal Gryzun PF07919.12 KZN83515.1 - 1.5e-232 773.6 0.0 1.8e-232 773.3 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 KZN83515.1 - 3.1e-109 364.5 3.3 1.2e-98 329.8 3.5 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.7 KZN83515.1 - 0.072 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Hydrolase_4 PF12146.8 KZN83516.1 - 2.9e-09 36.6 0.0 3.2e-07 29.9 0.0 2.6 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KZN83516.1 - 6.4e-09 36.7 5.6 8.7e-09 36.3 2.4 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KZN83516.1 - 2.5e-08 33.9 0.0 8.3e-08 32.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glutaredoxin PF00462.24 KZN83517.1 - 2.8e-12 46.7 0.0 1.1e-11 44.7 0.0 2.1 1 0 0 1 1 1 1 Glutaredoxin CAF1 PF04857.20 KZN83517.1 - 0.025 13.8 3.2 0.032 13.4 3.2 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease Conotoxin PF02950.17 KZN83517.1 - 0.048 14.7 1.6 5.8 8.0 0.0 2.4 2 0 0 2 2 2 0 Conotoxin BSP_II PF05432.11 KZN83517.1 - 0.078 12.7 12.4 0.1 12.3 12.4 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) tRNA_anti-like PF12869.7 KZN83517.1 - 1.3 8.7 6.2 0.46 10.1 0.3 2.2 2 0 0 2 2 2 0 tRNA_anti-like Smg8_Smg9 PF10220.9 KZN83517.1 - 4.7 5.4 7.3 5.9 5.1 7.3 1.1 1 0 0 1 1 1 0 Smg8_Smg9 TFB6 PF17110.5 KZN83517.1 - 5 6.8 7.9 0.56 9.9 3.8 1.5 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Ribosomal_L6 PF00347.23 KZN83518.1 - 1.2e-22 80.4 3.7 1.4e-10 41.7 1.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 DUF3336 PF11815.8 KZN83519.1 - 9.1e-38 129.1 0.0 2.2e-35 121.4 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3336) Patatin PF01734.22 KZN83519.1 - 1.7e-15 57.7 0.3 5.7e-15 56.0 0.1 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase TAFH PF07531.14 KZN83519.1 - 0.042 14.0 0.0 0.087 12.9 0.0 1.4 1 0 0 1 1 1 0 NHR1 homology to TAF Pkinase PF00069.25 KZN83520.1 - 2.3e-25 89.5 0.0 9.3e-25 87.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN83520.1 - 0.00065 19.1 0.1 0.0082 15.4 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Aa_trans PF01490.18 KZN83521.1 - 5.7e-34 117.5 44.3 1.2e-27 96.7 29.5 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Spore_permease PF03845.13 KZN83521.1 - 0.00053 18.9 14.4 0.00053 18.9 14.4 2.6 2 1 1 3 3 3 1 Spore germination protein AA_permease_2 PF13520.6 KZN83522.1 - 3e-42 145.0 50.0 3.7e-42 144.6 50.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN83522.1 - 1.7e-24 86.3 43.7 2.3e-24 85.8 43.7 1.1 1 0 0 1 1 1 1 Amino acid permease PhoD PF09423.10 KZN83523.1 - 1.3e-09 37.6 3.3 3.4e-05 23.0 0.6 3.0 2 1 0 2 2 2 2 PhoD-like phosphatase Pox_A31 PF05771.11 KZN83526.1 - 0.16 11.9 0.2 0.94 9.5 0.1 1.9 2 0 0 2 2 2 0 Poxvirus A31 protein Rhomboid PF01694.22 KZN83528.1 - 2.9e-20 72.8 10.6 4.5e-20 72.2 9.7 1.7 2 0 0 2 2 2 1 Rhomboid family Shugoshin_N PF07558.11 KZN83529.1 - 0.04 13.8 0.3 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Mob1_phocein PF03637.17 KZN83530.1 - 8.6e-51 172.3 0.0 3.7e-50 170.3 0.0 1.8 1 1 0 1 1 1 1 Mob1/phocein family NdhO PF11910.8 KZN83530.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Cyanobacterial and plant NDH-1 subunit O Leo1 PF04004.13 KZN83531.1 - 4.9e-26 91.5 2.6 5.4e-26 91.4 0.0 2.3 2 1 0 2 2 2 1 Leo1-like protein BOP1NT PF08145.12 KZN83532.1 - 1.7e-108 362.5 7.2 2.5e-108 361.9 7.2 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KZN83532.1 - 7.6e-24 83.5 5.6 9e-10 39.0 0.2 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN83532.1 - 4.2e-06 27.0 0.0 0.02 15.2 0.0 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nop53 PF07767.11 KZN83532.1 - 0.068 12.6 0.2 0.068 12.6 0.2 2.0 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) AAA PF00004.29 KZN83533.1 - 2.1e-89 296.8 0.0 1e-43 148.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KZN83533.1 - 7e-23 80.2 1.3 3.6e-10 39.5 0.2 2.9 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 KZN83533.1 - 1.1e-13 51.3 0.0 2.6e-06 27.3 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KZN83533.1 - 1.2e-13 51.8 1.2 0.00021 21.7 0.0 4.5 2 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 KZN83533.1 - 5.9e-12 46.0 0.6 0.015 15.6 0.0 5.2 4 2 2 6 6 4 2 AAA domain AAA_2 PF07724.14 KZN83533.1 - 1.8e-10 41.2 0.0 0.00022 21.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KZN83533.1 - 1.8e-10 41.0 0.2 0.0014 18.6 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KZN83533.1 - 4.2e-10 39.9 0.0 0.00013 22.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.13 KZN83533.1 - 9.7e-09 34.9 0.1 0.00013 21.3 0.0 2.5 2 1 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 KZN83533.1 - 4.9e-08 33.1 0.0 0.0023 18.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KZN83533.1 - 1.2e-07 32.1 0.0 0.0077 16.6 0.0 2.7 2 1 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 KZN83533.1 - 9.4e-07 28.7 0.1 0.045 13.5 0.0 2.8 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 KZN83533.1 - 1e-06 29.3 0.0 0.026 15.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KZN83533.1 - 1.7e-06 27.5 0.3 0.045 13.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KZN83533.1 - 2.2e-06 27.6 0.0 0.0077 16.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KZN83533.1 - 2.7e-06 27.7 0.0 0.03 14.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KZN83533.1 - 4.3e-06 26.1 0.0 0.06 12.6 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin ATPase PF06745.13 KZN83533.1 - 9.1e-06 25.2 0.1 0.37 10.1 0.0 3.5 2 1 0 3 3 3 2 KaiC Rad17 PF03215.15 KZN83533.1 - 1.7e-05 24.9 0.0 0.086 12.7 0.0 2.6 2 1 0 2 2 2 2 Rad17 P-loop domain AAA_7 PF12775.7 KZN83533.1 - 1.9e-05 24.2 0.0 0.072 12.6 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 KZN83533.1 - 2.6e-05 23.9 0.4 2.6 7.6 0.0 3.8 2 1 1 3 3 3 2 AAA domain TsaE PF02367.17 KZN83533.1 - 3e-05 24.0 0.0 0.14 12.2 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin2 PF13189.6 KZN83533.1 - 5.3e-05 23.4 0.0 0.0082 16.3 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family NACHT PF05729.12 KZN83533.1 - 5.3e-05 23.2 0.2 1 9.3 0.0 3.6 3 1 1 4 4 3 2 NACHT domain AAA_17 PF13207.6 KZN83533.1 - 5.5e-05 23.6 0.2 0.18 12.2 0.2 3.3 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KZN83533.1 - 7.4e-05 23.3 0.0 0.35 11.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter Sigma54_activat PF00158.26 KZN83533.1 - 0.00013 21.7 0.0 0.3 10.8 0.0 2.9 3 0 0 3 3 3 2 Sigma-54 interaction domain PhoH PF02562.16 KZN83533.1 - 0.00016 21.2 0.0 0.24 10.8 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein NB-ARC PF00931.22 KZN83533.1 - 0.00058 19.1 0.0 0.98 8.5 0.0 3.1 3 0 0 3 3 3 1 NB-ARC domain Sigma54_activ_2 PF14532.6 KZN83533.1 - 0.00085 19.4 0.0 1.9 8.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_11 PF13086.6 KZN83533.1 - 0.00097 19.0 0.0 1.6 8.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain SKI PF01202.22 KZN83533.1 - 0.00099 19.3 0.0 1.1 9.4 0.0 2.7 2 0 0 2 2 2 1 Shikimate kinase AAA_24 PF13479.6 KZN83533.1 - 0.0014 18.4 0.0 0.98 9.1 0.0 2.8 3 0 0 3 3 2 1 AAA domain AFG1_ATPase PF03969.16 KZN83533.1 - 0.002 17.1 0.2 0.53 9.1 0.0 2.8 3 1 0 3 3 3 1 AFG1-like ATPase TniB PF05621.11 KZN83533.1 - 0.002 17.5 0.0 1.9 7.9 0.0 3.3 3 0 0 3 3 3 1 Bacterial TniB protein Parvo_NS1 PF01057.17 KZN83533.1 - 0.0023 17.1 0.0 1.6 7.8 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 KZN83533.1 - 0.0028 17.6 0.0 1.7 8.5 0.0 3.3 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 KZN83533.1 - 0.0067 16.2 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 KZN83533.1 - 0.0074 15.5 0.0 0.085 12.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 KZN83533.1 - 0.018 15.4 1.5 7.7 6.8 0.2 3.1 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KZN83533.1 - 0.019 14.2 0.0 1.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SRPRB PF09439.10 KZN83533.1 - 0.044 13.2 0.0 29 4.0 0.0 3.3 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit CPT PF07931.12 KZN83533.1 - 0.048 13.5 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein IPT PF01745.16 KZN83533.1 - 0.052 12.9 0.0 5.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase NTPase_1 PF03266.15 KZN83533.1 - 0.058 13.3 0.0 6.7 6.6 0.0 2.8 2 1 1 3 3 3 0 NTPase ResIII PF04851.15 KZN83533.1 - 0.063 13.3 0.0 17 5.4 0.0 2.7 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KZN83533.1 - 0.15 11.7 0.1 29 4.3 0.0 2.7 3 0 0 3 3 2 0 AAA domain Bac_DnaA PF00308.18 KZN83533.1 - 0.17 11.7 0.0 4.3 7.1 0.0 2.9 3 1 0 3 3 3 0 Bacterial dnaA protein Hydin_ADK PF17213.3 KZN83533.1 - 0.39 11.0 1.7 4.3 7.6 0.0 3.0 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain Snf7 PF03357.21 KZN83534.1 - 6.4e-11 42.1 1.6 8.7e-11 41.7 1.6 1.1 1 0 0 1 1 1 1 Snf7 MR_MLE_N PF02746.16 KZN83534.1 - 0.058 13.6 0.0 0.078 13.2 0.0 1.2 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain PITH PF06201.13 KZN83535.1 - 1.1e-41 142.6 0.0 1.3e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 PITH domain HA2 PF04408.23 KZN83536.1 - 2.6e-16 59.8 0.1 5e-16 58.9 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KZN83536.1 - 9.1e-13 48.4 0.0 1.8e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KZN83536.1 - 1.7e-11 44.5 0.0 3.6e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KZN83536.1 - 8e-06 26.2 0.0 1.9e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KZN83536.1 - 3.4e-05 23.7 0.0 6.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KZN83536.1 - 0.00015 22.1 0.1 0.0017 18.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KZN83536.1 - 0.00025 20.8 0.0 0.0005 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 KZN83536.1 - 0.006 16.2 0.1 0.11 12.0 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 KZN83536.1 - 0.0077 15.3 0.0 0.019 14.0 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.6 KZN83536.1 - 0.046 13.8 0.0 4.2 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Herpes_ori_bp PF02399.15 KZN83536.1 - 0.066 11.3 0.0 0.093 10.8 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein Zeta_toxin PF06414.12 KZN83536.1 - 0.097 11.9 0.3 0.39 10.0 0.1 2.0 1 1 1 2 2 2 0 Zeta toxin DUF2075 PF09848.9 KZN83536.1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 KZN83536.1 - 0.14 12.3 0.2 0.57 10.3 0.2 2.0 2 1 0 2 2 2 0 AAA domain FBPase_2 PF06874.11 KZN83536.1 - 0.15 10.3 0.0 0.24 9.6 0.0 1.2 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase AAA_23 PF13476.6 KZN83536.1 - 0.21 12.1 0.0 0.41 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain CUE PF02845.16 KZN83537.1 - 1.6e-10 40.5 0.0 2.5e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 CUE domain AFOR_C PF01314.18 KZN83537.1 - 0.18 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 UBA_4 PF14555.6 KZN83537.1 - 0.18 11.6 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain MOZART1 PF12554.8 KZN83538.1 - 2.5e-24 84.8 1.7 3e-24 84.5 1.7 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated DUF1844 PF08899.11 KZN83538.1 - 0.0024 18.1 0.4 0.0037 17.5 0.2 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1844) SRP54_N PF02881.19 KZN83538.1 - 0.035 14.3 0.2 0.065 13.5 0.1 1.5 1 1 0 1 1 1 0 SRP54-type protein, helical bundle domain DHHA1 PF02272.19 KZN83538.1 - 0.074 13.5 0.1 0.091 13.2 0.1 1.1 1 0 0 1 1 1 0 DHHA1 domain Metallophos PF00149.28 KZN83539.1 - 3e-05 24.6 0.3 4.4e-05 24.1 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Acetyltransf_1 PF00583.25 KZN83540.1 - 1.4e-10 41.4 0.1 1.7e-10 41.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KZN83540.1 - 3.3e-09 36.6 0.0 5.2e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KZN83540.1 - 1.3e-06 28.8 0.1 1.7e-06 28.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KZN83540.1 - 4.3e-06 26.7 0.0 5.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 KZN83540.1 - 0.00035 20.3 0.3 0.00055 19.7 0.3 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_6 PF13480.7 KZN83540.1 - 0.0011 19.2 0.0 0.0014 18.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KZN83540.1 - 0.0041 17.3 0.0 0.0058 16.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KZN83540.1 - 0.015 15.4 0.0 0.027 14.6 0.0 1.4 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase He_PIG PF05345.12 KZN83541.1 - 2.3e-15 56.5 4.9 0.00025 21.2 0.0 4.4 4 0 0 4 4 4 3 Putative Ig domain SKG6 PF08693.10 KZN83541.1 - 6.3e-07 28.7 0.4 1.2e-06 27.8 0.4 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 KZN83541.1 - 0.019 14.8 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) PP2C PF00481.21 KZN83542.1 - 2e-80 270.2 0.0 3e-80 269.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C CTP_transf_like PF01467.26 KZN83543.1 - 3.9e-29 101.7 0.0 6.4e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like HIGH_NTase1 PF05636.11 KZN83543.1 - 0.2 10.8 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase EamA PF00892.20 KZN83544.1 - 3e-19 69.5 31.1 1.9e-13 50.7 8.7 2.5 2 1 0 2 2 2 2 EamA-like transporter family DUF4728 PF15860.5 KZN83544.1 - 0.0084 16.8 0.8 0.0084 16.8 0.8 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4728) UTP25 PF06862.12 KZN83545.1 - 1.7e-191 637.1 0.0 2e-191 636.9 0.0 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 FXMRP1_C_core PF12235.8 KZN83545.1 - 3.6 8.2 17.0 0.21 12.2 10.5 2.3 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal JAB PF01398.21 KZN83546.1 - 1.1e-19 70.6 0.0 2.3e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KZN83546.1 - 1.9e-19 70.1 0.5 3.2e-19 69.4 0.5 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.13 KZN83546.1 - 0.001 19.1 0.0 0.0031 17.6 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) TFIID-18kDa PF02269.16 KZN83547.1 - 1.3e-23 82.8 0.0 2.1e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-S PF15630.6 KZN83547.1 - 0.001 19.4 0.0 0.0019 18.5 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 KZN83547.1 - 0.004 17.5 0.0 0.004 17.5 0.0 2.7 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 KZN83547.1 - 0.0048 17.4 0.0 0.0093 16.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Bromo_TP PF07524.13 KZN83547.1 - 0.0065 16.5 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 KZN83547.1 - 0.0094 16.2 0.9 0.05 13.9 0.1 2.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KZN83547.1 - 0.015 15.4 0.2 0.033 14.3 0.2 1.6 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KZN83547.1 - 0.027 14.6 0.1 0.053 13.7 0.1 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.15 KZN83547.1 - 0.14 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Herpes_BLLF1 PF05109.13 KZN83547.1 - 1.3 6.9 32.5 1.9 6.3 32.5 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) cwf18 PF08315.12 KZN83548.1 - 2.3e-44 151.3 6.0 2.3e-44 151.3 6.0 1.4 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor SUZ PF12752.7 KZN83549.1 - 7.6e-15 55.4 5.1 7.6e-15 55.4 5.1 3.9 3 1 0 3 3 3 1 SUZ domain R3H PF01424.22 KZN83549.1 - 2e-06 27.7 0.0 4.3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 R3H domain MTBP_C PF14920.6 KZN83549.1 - 0.43 10.3 2.8 0.2 11.3 0.3 1.6 2 0 0 2 2 2 0 MDM2-binding UCR_Fe-S_N PF10399.9 KZN83550.1 - 0.23 10.9 0.1 0.23 10.9 0.1 1.9 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF865 PF05906.11 KZN83550.1 - 3.1 7.7 5.6 2.2 8.1 1.3 2.4 2 0 0 2 2 2 0 Herpesvirus-7 repeat of unknown function (DUF865) Ribosomal_L17 PF01196.19 KZN83551.1 - 6.3e-30 103.9 0.1 4.3e-29 101.3 0.1 2.2 2 0 0 2 2 2 1 Ribosomal protein L17 Mg_chelatase_C PF13335.6 KZN83551.1 - 0.52 11.0 5.2 0.18 12.5 1.0 2.1 2 1 1 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal AIM5 PF17050.5 KZN83552.1 - 3.6e-13 50.1 4.2 4.9e-13 49.7 4.2 1.2 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 DUF5315 PF17242.2 KZN83553.1 - 7.7e-26 89.7 0.8 1.9e-25 88.5 0.8 1.6 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) Ribosom_S12_S23 PF00164.25 KZN83554.1 - 1.6e-50 169.5 0.8 2e-50 169.2 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 IF-2B PF01008.17 KZN83555.1 - 8.1e-64 215.5 0.2 3.6e-38 131.4 0.0 2.3 2 1 0 2 2 2 2 Initiation factor 2 subunit family TALPID3 PF15324.6 KZN83555.1 - 0.14 9.8 0.3 0.19 9.3 0.3 1.1 1 0 0 1 1 1 0 Hedgehog signalling target NIF PF03031.18 KZN83556.1 - 6e-59 198.3 0.0 1.2e-58 197.3 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Metallophos PF00149.28 KZN83557.1 - 1.8e-16 61.3 0.4 2.1e-16 61.0 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_76 PF03663.14 KZN83558.1 - 3e-147 491.0 24.9 3.8e-147 490.6 24.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 MFS_1 PF07690.16 KZN83559.1 - 1.9e-30 106.0 55.1 5.8e-29 101.1 32.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN83559.1 - 1.4e-06 27.5 23.8 2.5e-05 23.3 23.8 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter Nucleoside_tran PF01733.18 KZN83559.1 - 0.0058 16.1 0.9 0.0058 16.1 0.9 1.7 2 0 0 2 2 2 1 Nucleoside transporter MFS_1 PF07690.16 KZN83560.1 - 3.6e-31 108.4 34.6 8e-31 107.2 34.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KZN83560.1 - 0.00092 18.6 5.5 0.00092 18.6 5.5 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Orf78 PF06024.12 KZN83560.1 - 0.11 12.7 0.1 0.23 11.8 0.1 1.4 1 0 0 1 1 1 0 Orf78 (ac78) DUF2834 PF11196.8 KZN83560.1 - 2.5 8.5 8.5 0.4 11.1 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2834) MFS_1 PF07690.16 KZN83561.1 - 4.9e-36 124.4 28.9 4.9e-36 124.4 28.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN83561.1 - 5.1e-13 48.7 9.0 5.1e-13 48.7 9.0 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KZN83561.1 - 8.6e-06 24.4 4.1 8.6e-06 24.4 4.1 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.18 KZN83562.1 - 9.1e-20 70.8 0.2 1.3e-19 70.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KZN83563.1 - 0.00075 18.5 0.1 0.00078 18.4 0.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter N2227 PF07942.12 KZN83564.1 - 7.7e-58 195.8 0.0 1.7e-57 194.7 0.0 1.5 2 0 0 2 2 2 1 N2227-like protein Methyltransf_11 PF08241.12 KZN83564.1 - 0.00083 20.0 0.0 0.0044 17.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN83564.1 - 0.0029 18.3 0.1 0.024 15.3 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN83564.1 - 0.0033 17.3 0.0 0.0081 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN83564.1 - 0.021 15.5 0.0 0.15 12.8 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Homez PF11569.8 KZN83565.1 - 0.1 12.1 0.1 48 3.5 0.0 3.0 3 0 0 3 3 3 0 Homeodomain leucine-zipper encoding, Homez HECT PF00632.25 KZN83566.1 - 9.6e-96 320.9 0.0 1.3e-95 320.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KZN83566.1 - 4.4e-32 109.8 20.5 1.4e-12 47.4 3.1 4.1 4 0 0 4 4 4 3 WW domain C2 PF00168.30 KZN83566.1 - 5.5e-19 68.4 0.0 1.4e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 C2 domain Rrn6 PF10214.9 KZN83566.1 - 0.059 11.9 8.9 0.086 11.3 8.9 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor RRM_1 PF00076.22 KZN83567.1 - 2.4e-15 56.1 0.0 4.1e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KZN83567.1 - 0.014 15.3 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Spc7 PF08317.11 KZN83567.1 - 0.017 14.0 5.2 0.022 13.7 5.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein COG6 PF06419.11 KZN83567.1 - 0.022 13.0 0.2 0.026 12.7 0.2 1.0 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 BLOC1_2 PF10046.9 KZN83567.1 - 0.03 14.6 2.0 0.049 13.9 2.0 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3450 PF11932.8 KZN83567.1 - 0.046 13.0 4.1 0.061 12.6 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) NPV_P10 PF05531.12 KZN83567.1 - 0.052 14.0 0.5 0.1 13.1 0.5 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF724 PF05266.14 KZN83567.1 - 0.17 11.7 4.6 0.24 11.2 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.19 KZN83567.1 - 0.23 9.4 0.5 0.27 9.1 0.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TRAP_alpha PF03896.16 KZN83567.1 - 0.26 10.4 3.1 0.35 10.0 3.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Troponin PF00992.20 KZN83567.1 - 0.29 11.4 6.3 0.43 10.9 6.3 1.2 1 0 0 1 1 1 0 Troponin ZapB PF06005.12 KZN83567.1 - 0.46 11.0 6.5 0.82 10.2 6.5 1.3 1 0 0 1 1 1 0 Cell division protein ZapB APG6_N PF17675.1 KZN83567.1 - 0.88 10.1 8.8 1.2 9.6 8.8 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 KZN83567.1 - 0.91 9.3 4.6 1.4 8.7 4.6 1.3 1 0 0 1 1 1 0 Septum formation initiator Metallophos_2 PF12850.7 KZN83568.1 - 6.5e-09 36.2 0.0 7.4e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aminotran_5 PF00266.19 KZN83569.1 - 3.9e-28 98.5 0.0 5.2e-28 98.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V MFS_1 PF07690.16 KZN83571.1 - 1.6e-24 86.5 37.5 1.6e-24 86.5 37.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily ATP-synt_I PF03899.15 KZN83571.1 - 0.57 10.6 20.7 0.045 14.1 3.7 3.2 2 2 0 2 2 2 0 ATP synthase I chain Zn_clus PF00172.18 KZN83572.1 - 6.9e-08 32.5 10.7 1.4e-07 31.5 10.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN83572.1 - 1.1e-07 31.2 0.8 1.6e-07 30.7 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain AhpC-TSA PF00578.21 KZN83573.1 - 0.0037 17.2 0.0 0.0053 16.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Pkinase PF00069.25 KZN83574.1 - 3.6e-09 36.4 0.0 5e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KZN83574.1 - 2.4e-05 23.8 0.0 3.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KZN83574.1 - 0.0034 16.7 0.0 0.0045 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KZN83574.1 - 0.017 15.1 0.1 0.036 14.0 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KZN83574.1 - 0.024 14.2 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family WaaY PF06176.11 KZN83574.1 - 0.034 13.7 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.23 KZN83575.1 - 5.2e-10 39.6 0.0 1.4e-09 38.3 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN83575.1 - 1.8e-07 31.0 0.1 4.3e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 KZN83575.1 - 0.00061 18.8 0.1 0.0023 16.9 0.0 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1679) DUF3297 PF11730.8 KZN83575.1 - 0.009 15.9 0.7 0.018 14.9 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3297) EcKinase PF02958.20 KZN83575.1 - 0.017 14.4 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase PF00069.25 KZN83575.1 - 0.02 14.3 0.4 1.2 8.4 0.0 2.8 2 1 1 3 3 3 0 Protein kinase domain Pox_ser-thr_kin PF05445.11 KZN83575.1 - 0.02 13.8 0.1 0.078 11.9 0.0 1.8 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase ESCRT-II PF05871.12 KZN83575.1 - 0.1 12.9 0.3 0.23 11.7 0.3 1.5 1 0 0 1 1 1 0 ESCRT-II complex subunit AcetylCoA_hyd_C PF13336.6 KZN83575.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain Kdo PF06293.14 KZN83575.1 - 0.14 11.5 1.3 0.67 9.3 0.0 2.3 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Zn_clus PF00172.18 KZN83576.1 - 0.00036 20.6 7.1 0.00036 20.6 7.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MLANA PF14991.6 KZN83577.1 - 0.27 11.5 1.9 4.9 7.5 0.6 2.1 1 1 1 2 2 2 0 Protein melan-A HHH PF00633.23 KZN83578.1 - 0.0018 18.0 0.1 0.0051 16.6 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF202 PF02656.15 KZN83581.1 - 1.1e-13 51.4 8.6 1.5e-13 51.0 5.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF5337 PF17272.2 KZN83581.1 - 6.1 6.7 10.0 0.6 10.0 4.7 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5337) DUF4131 PF13567.6 KZN83581.1 - 6.8 6.3 7.1 14 5.3 5.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) GMC_oxred_N PF00732.19 KZN83582.1 - 9.5e-54 182.8 0.0 1.2e-53 182.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KZN83582.1 - 7e-31 107.7 0.1 1.3e-30 106.8 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KZN83582.1 - 1.1e-05 24.7 1.6 0.012 14.7 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KZN83582.1 - 0.00059 19.2 0.7 0.0089 15.3 0.1 2.4 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KZN83582.1 - 0.0016 17.6 0.2 0.0033 16.5 0.2 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KZN83582.1 - 0.0031 16.8 0.5 0.48 9.6 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KZN83582.1 - 0.063 12.8 5.8 0.043 13.4 1.4 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KZN83582.1 - 0.067 12.4 0.1 0.16 11.2 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN83582.1 - 0.077 13.2 0.4 0.21 11.8 0.4 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Zn_clus PF00172.18 KZN83583.1 - 5.9e-10 39.1 10.0 1e-09 38.4 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KZN83583.1 - 1.5e-07 30.6 0.3 2e-07 30.2 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain HATPase_c PF02518.26 KZN83585.1 - 3.5e-13 50.1 0.0 5.4e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Methyltransf_25 PF13649.6 KZN83586.1 - 1e-13 51.8 0.0 1.6e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN83586.1 - 1.4e-11 44.9 0.0 2.1e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN83586.1 - 1.2e-09 38.1 0.0 1.9e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN83586.1 - 2.6e-08 33.9 0.0 3.4e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN83586.1 - 1.6e-07 32.0 0.0 2.3e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KZN83586.1 - 0.00016 21.1 0.1 0.00022 20.6 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KZN83586.1 - 0.00023 20.8 0.1 0.00034 20.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KZN83586.1 - 0.00068 19.1 0.6 0.001 18.5 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KZN83586.1 - 0.019 14.7 0.1 0.027 14.2 0.1 1.2 1 0 0 1 1 1 0 Lysine methyltransferase MetW PF07021.12 KZN83586.1 - 0.067 12.8 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW N6_N4_Mtase PF01555.18 KZN83586.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.4 2 0 0 2 2 2 0 DNA methylase p450 PF00067.22 KZN83587.1 - 1.3e-53 182.4 0.0 2e-53 181.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 KZN83589.1 - 1.4e-23 83.2 0.3 2.4e-23 82.4 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KZN83589.1 - 0.0035 17.4 0.2 0.0076 16.3 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like LytR_C PF13399.6 KZN83589.1 - 0.018 16.0 0.2 0.053 14.5 0.2 1.8 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator DUF373 PF04123.13 KZN83590.1 - 2.6 7.4 7.5 3.8 6.9 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) NmrA PF05368.13 KZN83593.1 - 3.4e-16 59.5 0.0 1.6e-15 57.3 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KZN83593.1 - 6.5e-14 52.2 0.0 1e-13 51.6 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KZN83593.1 - 2.9e-09 36.8 0.1 1.2e-06 28.1 0.0 2.6 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KZN83593.1 - 0.00012 22.4 0.1 0.0002 21.6 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KZN83593.1 - 0.00041 20.3 0.0 0.00066 19.6 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KZN83593.1 - 0.0059 15.8 0.0 0.0097 15.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 KZN83593.1 - 0.0082 15.3 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KZN83593.1 - 0.012 14.7 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.20 KZN83593.1 - 0.019 15.0 0.5 0.16 12.1 0.3 2.4 2 1 1 3 3 3 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 KZN83593.1 - 0.045 13.2 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DUF3400 PF11880.8 KZN83593.1 - 0.061 12.9 0.1 0.16 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) F420_oxidored PF03807.17 KZN83593.1 - 0.066 13.8 0.2 0.17 12.5 0.1 1.8 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent COesterase PF00135.28 KZN83594.1 - 8.8e-65 219.5 0.0 1.1e-64 219.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KZN83594.1 - 1.4e-05 25.1 0.0 3e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KZN83594.1 - 0.0026 17.3 0.0 0.0071 15.8 0.0 1.7 1 0 0 1 1 1 1 Prolyl oligopeptidase family RuBisCO_large_N PF02788.16 KZN83594.1 - 0.14 12.3 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain Pkinase PF00069.25 KZN83595.1 - 6.4e-25 88.0 0.0 1.1e-22 80.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN83595.1 - 8.2e-08 31.8 0.0 0.011 15.0 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KZN83595.1 - 0.074 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Glyco_hydro_3_C PF01915.22 KZN83597.1 - 1.4e-57 194.9 0.0 2.1e-57 194.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KZN83597.1 - 1.6e-39 136.2 0.0 3.3e-39 135.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KZN83597.1 - 1.3e-25 89.3 0.0 2.7e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KZN83597.1 - 1.5e-14 54.1 0.0 2.8e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Sugar_tr PF00083.24 KZN83598.1 - 7.5e-76 255.8 21.6 9.1e-76 255.5 21.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN83598.1 - 7.2e-22 77.8 18.5 7.2e-22 77.8 18.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily COX7C PF02935.16 KZN83598.1 - 0.22 11.8 1.1 14 6.0 0.5 2.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc ADH_N PF08240.12 KZN83600.1 - 1.5e-18 66.7 5.2 2.7e-18 65.8 5.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN83600.1 - 9.7e-12 45.0 0.0 1.5e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KZN83600.1 - 0.00029 20.2 0.1 0.0005 19.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KZN83600.1 - 0.0025 17.1 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF521 PF04412.13 KZN83601.1 - 1.2e-141 472.1 0.0 3.8e-141 470.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF521) DUF126 PF01989.16 KZN83601.1 - 2.7e-29 100.8 0.0 5.7e-29 99.7 0.0 1.6 1 0 0 1 1 1 1 Aconitase X swivel domain Aminotran_1_2 PF00155.21 KZN83602.1 - 2.9e-51 174.8 0.0 3.5e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cas_Cas1 PF01867.16 KZN83602.1 - 0.076 12.1 0.1 0.26 10.4 0.0 1.9 3 0 0 3 3 3 0 CRISPR associated protein Cas1 DUF2663 PF10864.8 KZN83604.1 - 0.073 13.5 5.0 0.16 12.4 1.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2663) V_ATPase_I PF01496.19 KZN83604.1 - 5.1 4.9 23.3 0.043 11.7 11.4 2.2 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family MACPF PF01823.19 KZN83605.1 - 4.4e-11 43.3 1.2 9.7e-11 42.2 1.2 1.5 1 0 0 1 1 1 1 MAC/Perforin domain Con-6 PF10346.9 KZN83606.1 - 5.3e-27 93.5 1.2 4.7e-16 58.5 0.3 2.2 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.7 KZN83606.1 - 0.032 14.1 1.6 0.051 13.4 0.4 1.7 1 1 1 2 2 2 0 SpoIIIAH-like protein GHL5 PF14872.6 KZN83606.1 - 0.1 10.6 0.0 0.12 10.4 0.0 1.0 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 MIP PF00230.20 KZN83607.1 - 1.3e-33 116.7 3.5 1.7e-33 116.3 3.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein Gly-zipper_Omp PF13488.6 KZN83607.1 - 0.1 12.6 3.9 1.3 9.1 0.0 3.2 3 0 0 3 3 3 0 Glycine zipper DMT_YdcZ PF04657.13 KZN83607.1 - 0.18 12.1 3.8 0.19 12.0 0.1 2.6 2 1 0 2 2 2 0 Putative inner membrane exporter, YdcZ PALP PF00291.25 KZN83608.1 - 8.2e-50 169.9 0.0 9.9e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF19 PF01579.18 KZN83609.1 - 0.012 15.4 0.1 0.016 15.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF19) XET_C PF06955.12 KZN83609.1 - 0.053 13.4 1.2 0.088 12.7 1.2 1.4 1 0 0 1 1 1 0 Xyloglucan endo-transglycosylase (XET) C-terminus Tctex-1 PF03645.13 KZN83611.1 - 1.7e-34 118.2 0.0 2e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family WD40 PF00400.32 KZN83612.1 - 8.8e-34 115.0 16.0 2.1e-10 41.0 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN83612.1 - 1.7e-10 41.0 0.8 0.043 14.1 0.0 4.5 2 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KZN83612.1 - 3.6e-06 26.2 0.1 0.37 9.7 0.0 4.1 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KZN83612.1 - 3.7e-05 22.6 4.4 0.24 10.0 0.1 3.6 2 1 1 3 3 3 3 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KZN83612.1 - 0.00011 21.3 2.3 0.00012 21.2 0.1 2.1 3 0 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Hira PF07569.11 KZN83612.1 - 0.028 14.2 1.1 0.77 9.4 0.4 3.3 2 1 1 3 3 3 0 TUP1-like enhancer of split Frtz PF11768.8 KZN83612.1 - 0.086 11.1 0.0 0.14 10.5 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz HPS3_N PF14761.6 KZN83612.1 - 0.17 11.4 0.0 0.54 9.8 0.0 1.7 1 1 0 1 1 1 0 Hermansky-Pudlak syndrome 3 Mod_r PF07200.13 KZN83613.1 - 0.00074 19.6 7.2 0.0012 19.0 7.2 1.3 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Vps5 PF09325.10 KZN83613.1 - 0.038 13.5 3.4 0.059 12.9 3.4 1.2 1 0 0 1 1 1 0 Vps5 C terminal like DUF3584 PF12128.8 KZN83613.1 - 0.053 11.0 6.8 0.072 10.6 6.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) BLOC1_2 PF10046.9 KZN83613.1 - 0.078 13.3 2.1 0.16 12.3 2.1 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1178 PF06676.11 KZN83613.1 - 0.17 12.3 0.8 0.35 11.3 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) APG6_N PF17675.1 KZN83613.1 - 0.62 10.6 8.4 0.94 10.0 8.4 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Cnn_1N PF07989.11 KZN83613.1 - 0.71 10.1 5.1 2.5 8.3 5.1 1.9 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 Csm1_N PF18504.1 KZN83613.1 - 0.81 10.1 5.3 0.84 10.0 1.9 2.2 2 0 0 2 2 2 0 Csm1 N-terminal domain ADIP PF11559.8 KZN83613.1 - 1.4 9.0 11.6 1.9 8.5 11.6 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding CENP-H PF05837.12 KZN83613.1 - 3.4 8.1 7.1 5 7.6 6.5 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) LysM PF01476.20 KZN83615.1 - 0.0003 20.8 0.0 0.00043 20.3 0.0 1.3 1 0 0 1 1 1 1 LysM domain MFS_1 PF07690.16 KZN83616.1 - 6.8e-31 107.5 38.0 2.6e-29 102.2 30.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN83616.1 - 3e-09 36.2 4.8 3e-09 36.2 4.8 2.6 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KZN83616.1 - 1.9e-07 29.9 1.6 1.9e-07 29.9 1.6 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) AIP3 PF03915.13 KZN83617.1 - 2.2e-153 511.2 1.2 2.2e-153 511.2 1.2 2.2 2 0 0 2 2 2 1 Actin interacting protein 3 Lectin_N PF03954.14 KZN83617.1 - 0.0038 17.0 6.2 0.0045 16.7 0.0 3.0 3 0 0 3 3 3 1 Hepatic lectin, N-terminal domain NPV_P10 PF05531.12 KZN83617.1 - 0.99 9.9 0.0 0.99 9.9 0.0 2.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Sec34 PF04136.15 KZN83617.1 - 1.1 9.2 3.2 6.2 6.7 0.1 3.0 3 0 0 3 3 3 0 Sec34-like family Cytochrom_C_2 PF01322.20 KZN83617.1 - 2.4 9.1 8.7 4.4 8.2 3.0 3.9 4 0 0 4 4 4 0 Cytochrome C' LsmAD PF06741.13 KZN83618.1 - 1.7e-28 98.9 2.0 1.7e-28 98.9 2.0 1.9 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 KZN83618.1 - 1.3e-20 73.3 0.1 3.6e-20 71.9 0.0 1.8 2 0 0 2 2 2 1 Ataxin 2 SM domain Pkinase PF00069.25 KZN83619.1 - 5.2e-12 45.7 0.0 1.1e-11 44.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN83619.1 - 1.6e-07 30.9 0.0 2.9e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 KZN83619.1 - 1.8e-07 30.8 0.0 0.092 13.0 0.0 4.2 3 0 0 3 3 3 2 HEAT repeat Cnd1 PF12717.7 KZN83619.1 - 1.2e-06 28.7 0.1 2.9e-06 27.4 0.1 1.7 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KZN83619.1 - 0.0013 19.2 0.2 4.8 7.8 0.2 3.1 2 0 0 2 2 2 2 HEAT-like repeat Adaptin_N PF01602.20 KZN83619.1 - 0.012 14.2 0.0 0.017 13.7 0.0 1.1 1 0 0 1 1 1 0 Adaptin N terminal region Kinase-like PF14531.6 KZN83619.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like HEAT_2 PF13646.6 KZN83619.1 - 0.015 15.6 0.1 0.23 11.9 0.1 2.5 1 1 2 3 3 3 0 HEAT repeats CoA_trans PF01144.23 KZN83619.1 - 0.034 13.5 0.0 0.076 12.4 0.0 1.5 1 0 0 1 1 1 0 Coenzyme A transferase Amino_oxidase PF01593.24 KZN83621.1 - 1.7e-63 215.5 0.0 1.9e-63 215.3 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KZN83621.1 - 3.6e-12 46.3 0.2 6.6e-12 45.5 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KZN83621.1 - 3.7e-08 33.3 0.4 2.2e-06 27.5 0.4 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KZN83621.1 - 1.8e-05 24.0 2.9 2.9e-05 23.3 2.9 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KZN83621.1 - 2.7e-05 24.6 0.4 7.6e-05 23.2 0.4 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KZN83621.1 - 4.4e-05 22.8 0.4 7.8e-05 22.0 0.4 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KZN83621.1 - 5.1e-05 22.6 0.4 0.00014 21.2 0.3 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KZN83621.1 - 6e-05 21.9 1.2 0.00061 18.6 1.4 2.0 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 KZN83621.1 - 7.1e-05 22.0 0.7 0.022 13.8 0.8 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KZN83621.1 - 9.2e-05 21.8 0.3 0.23 10.6 0.3 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KZN83621.1 - 0.00014 21.4 2.2 0.00019 20.9 2.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KZN83621.1 - 0.00021 20.6 0.5 0.00076 18.8 0.6 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 KZN83621.1 - 0.0027 17.7 0.5 0.054 13.5 0.3 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.22 KZN83621.1 - 0.0091 15.1 0.6 0.014 14.5 0.6 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KZN83621.1 - 0.0098 15.2 0.1 0.021 14.1 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Chromate_transp PF02417.15 KZN83623.1 - 4.6e-41 140.6 36.6 1.2e-36 126.2 11.5 2.4 3 0 0 3 3 3 2 Chromate transporter OAF PF14941.6 KZN83624.1 - 0.039 13.4 0.0 0.087 12.2 0.0 1.5 2 0 0 2 2 2 0 Transcriptional regulator, Out at first TMEM192 PF14802.6 KZN83624.1 - 0.23 10.5 0.8 9.2 5.3 0.2 2.2 2 0 0 2 2 2 0 TMEM192 family zf-MYND PF01753.18 KZN83625.1 - 3.2e-09 36.7 10.9 4.9e-09 36.1 10.9 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KZN83625.1 - 0.069 13.5 7.5 0.16 12.3 7.4 1.6 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding HATPase_c PF02518.26 KZN83630.1 - 2.9e-24 85.7 0.0 8.1e-24 84.3 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KZN83630.1 - 4.3e-24 84.8 0.4 1.1e-23 83.5 0.4 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KZN83630.1 - 8.9e-19 67.3 0.2 2.2e-18 66.1 0.2 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 KZN83630.1 - 1.1e-15 57.7 0.0 6.2e-10 39.1 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KZN83630.1 - 5.1e-14 52.4 0.0 1e-10 41.8 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 KZN83630.1 - 1.9e-11 44.2 0.0 2e-07 31.2 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 KZN83630.1 - 0.003 17.8 0.0 0.028 14.7 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 KZN83630.1 - 0.13 12.3 0.0 0.58 10.2 0.0 2.1 2 0 0 2 2 2 0 PAS domain Fungal_trans PF04082.18 KZN83632.1 - 1.5e-21 76.6 2.1 2.7e-21 75.8 2.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN83632.1 - 1.1e-07 31.8 9.5 1.1e-07 31.8 9.5 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ferritin_2 PF13668.6 KZN83633.1 - 6.2e-17 62.1 0.0 1e-16 61.4 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Sugar_tr PF00083.24 KZN83634.1 - 8.4e-08 31.5 1.4 8.6e-07 28.2 3.8 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter GFA PF04828.14 KZN83635.1 - 3.8e-10 40.0 0.7 8.3e-10 38.9 0.7 1.7 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Thioredoxin_4 PF13462.6 KZN83636.1 - 3.9e-09 36.9 0.0 7.4e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 KZN83636.1 - 0.0044 16.8 0.3 0.58 9.9 0.0 2.6 2 1 0 2 2 2 2 DSBA-like thioredoxin domain Phage_TAC_6 PF09550.10 KZN83636.1 - 0.02 15.3 0.1 0.042 14.3 0.1 1.5 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC LysM PF01476.20 KZN83637.1 - 6.6e-12 45.3 0.0 0.00021 21.3 0.0 3.3 3 0 0 3 3 3 3 LysM domain LysM PF01476.20 KZN83640.1 - 1.5e-17 63.3 0.4 3.8e-05 23.7 0.1 3.2 3 0 0 3 3 3 3 LysM domain UPF0203 PF05254.12 KZN83640.1 - 0.15 12.4 2.4 5.3 7.4 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) Sporozoite_P67 PF05642.11 KZN83640.1 - 0.28 9.2 4.6 0.39 8.7 4.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Hydrophobin PF01185.18 KZN83641.1 - 0.001 19.7 7.5 0.0015 19.1 7.5 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Granulin PF00396.18 KZN83641.1 - 0.063 13.6 1.7 0.063 13.6 1.7 2.3 2 0 0 2 2 2 0 Granulin CBM_14 PF01607.24 KZN83644.1 - 1.4e-07 31.5 2.7 2.3e-07 30.9 2.7 1.4 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain DUF3425 PF11905.8 KZN83645.1 - 1e-32 112.7 1.9 1.8e-32 111.9 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_2 PF07716.15 KZN83645.1 - 0.086 12.9 8.9 0.17 12.0 2.0 2.5 2 0 0 2 2 2 0 Basic region leucine zipper Herpes_UL6 PF01763.16 KZN83645.1 - 0.13 10.8 3.5 0.17 10.4 3.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like bZIP_1 PF00170.21 KZN83645.1 - 0.45 10.7 12.8 0.56 10.3 5.2 2.7 3 0 0 3 3 3 0 bZIP transcription factor MFS_1 PF07690.16 KZN83646.1 - 1.3e-48 165.7 39.7 1.3e-48 165.7 39.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN83646.1 - 2.1e-10 40.1 28.7 3.9e-10 39.2 28.7 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter HTH_7 PF02796.15 KZN83647.1 - 0.11 12.6 0.0 4.6 7.4 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Acetyltransf_1 PF00583.25 KZN83649.1 - 1.5e-10 41.4 0.0 2.2e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KZN83649.1 - 3.9e-07 30.1 0.2 5.5e-07 29.6 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KZN83649.1 - 1e-06 28.6 0.0 1.8e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KZN83649.1 - 9.7e-05 22.7 0.0 0.00018 21.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KZN83649.1 - 0.0043 17.1 0.2 0.0064 16.6 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SUR7 PF06687.12 KZN83651.1 - 4.2e-43 147.5 7.8 5.2e-43 147.2 7.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 KZN83651.1 - 0.45 10.4 15.1 0.16 11.9 11.5 2.0 2 1 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 TctB PF07331.11 KZN83651.1 - 0.58 10.4 13.5 1.1 9.6 10.9 2.5 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family adh_short_C2 PF13561.6 KZN83652.1 - 3.4e-53 180.6 0.1 3.9e-53 180.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN83652.1 - 7.3e-45 152.8 0.1 8.9e-45 152.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN83652.1 - 4.8e-11 42.9 0.2 6.4e-11 42.5 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KZN83652.1 - 2.9e-05 23.6 0.0 4.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KZN83652.1 - 0.004 16.3 0.0 0.0057 15.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF5046 PF16465.5 KZN83652.1 - 0.088 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5046) GDP_Man_Dehyd PF16363.5 KZN83652.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase HLH PF00010.26 KZN83653.1 - 5.6e-12 45.4 0.0 3e-11 43.1 0.0 2.2 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain Got1 PF04178.12 KZN83654.1 - 1.2e-36 125.6 16.9 1.7e-36 125.0 16.9 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family tRNA_lig_CPD PF08302.11 KZN83655.1 - 6.9e-93 310.7 0.0 9.9e-93 310.2 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.10 KZN83655.1 - 5.6e-83 278.1 0.0 9.2e-83 277.4 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 KZN83655.1 - 6.1e-49 166.3 0.0 1.1e-48 165.5 0.0 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_18 PF13238.6 KZN83655.1 - 0.0077 16.8 0.1 0.035 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain Ank_5 PF13857.6 KZN83656.1 - 1.7e-11 44.1 0.2 5.9e-09 36.0 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KZN83656.1 - 6.2e-07 29.9 0.1 3.1e-05 24.4 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN83656.1 - 9.3e-07 28.7 0.6 8.4e-05 22.7 0.1 3.2 3 1 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KZN83656.1 - 1.1e-06 29.1 0.2 2e-06 28.3 0.2 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KZN83656.1 - 0.0012 19.2 0.9 0.0048 17.3 0.1 2.4 3 0 0 3 3 3 1 Ankyrin repeat YejG PF13989.6 KZN83656.1 - 0.013 15.9 0.0 0.024 15.1 0.0 1.4 1 0 0 1 1 1 0 YejG-like protein Mod_r PF07200.13 KZN83657.1 - 1.8e-25 89.8 2.9 2.3e-25 89.4 2.9 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein RcbX PF02341.15 KZN83657.1 - 0.0047 17.2 0.1 0.008 16.4 0.1 1.4 1 0 0 1 1 1 1 RbcX protein Fib_alpha PF08702.10 KZN83657.1 - 0.0088 16.2 0.1 0.016 15.4 0.1 1.4 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family CDPS PF16715.5 KZN83657.1 - 0.75 9.4 4.9 1.4 8.5 0.3 2.1 1 1 1 2 2 2 0 Cyclodipeptide synthase PSK_trans_fac PF07704.11 KZN83657.1 - 1.5 9.7 5.2 0.48 11.2 1.1 2.0 2 0 0 2 2 2 0 Rv0623-like transcription factor PAP2 PF01569.21 KZN83658.1 - 1.1e-25 89.9 3.2 1.1e-25 89.9 3.2 1.9 3 0 0 3 3 3 1 PAP2 superfamily Sulf_transp PF04143.14 KZN83658.1 - 0.00014 21.6 2.3 0.0012 18.4 1.0 2.0 1 1 1 2 2 2 1 Sulphur transport DUF1206 PF06724.11 KZN83658.1 - 0.092 12.8 9.2 0.49 10.5 0.2 3.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1206) Spatacsin_C PF14649.6 KZN83659.1 - 0.08 12.0 0.4 0.12 11.4 0.4 1.1 1 0 0 1 1 1 0 Spatacsin C-terminus UCR_Fe-S_N PF10399.9 KZN83659.1 - 0.087 12.2 0.1 8.2 5.9 0.0 2.6 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Gpr1_Fun34_YaaH PF01184.19 KZN83661.1 - 6e-13 48.9 6.0 7e-13 48.7 6.0 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Amino_oxidase PF01593.24 KZN83662.1 - 1.4e-40 139.9 0.1 2.4e-40 139.2 0.1 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KZN83662.1 - 4.8e-05 23.5 0.0 0.00013 22.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KZN83662.1 - 0.012 14.9 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain DAGAT PF03982.13 KZN83662.1 - 0.18 10.7 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 Diacylglycerol acyltransferase Ctr PF04145.15 KZN83663.1 - 1.9e-34 119.4 3.3 2.6e-34 119.0 3.3 1.2 1 0 0 1 1 1 1 Ctr copper transporter family UPF0016 PF01169.19 KZN83663.1 - 0.0017 18.7 0.4 0.021 15.1 0.1 2.3 2 1 0 2 2 2 1 Uncharacterized protein family UPF0016 Ferric_reduct PF01794.19 KZN83664.1 - 2.4e-25 89.1 8.9 5.9e-25 87.8 8.9 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KZN83664.1 - 8.5e-17 61.7 0.0 1.2e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KZN83664.1 - 1e-07 32.0 0.0 2.2e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KZN83664.1 - 3.6e-07 30.8 0.0 9.5e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain CRAL_TRIO PF00650.20 KZN83665.1 - 5.2e-45 153.0 0.0 8.6e-45 152.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KZN83665.1 - 6.1e-11 42.3 0.0 1.7e-10 40.9 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KZN83665.1 - 1e-07 32.2 0.0 1.7e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Glyco_tranf_2_3 PF13641.6 KZN83666.1 - 2.1e-18 67.1 0.0 3e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KZN83666.1 - 3.1e-17 63.2 0.1 4.6e-17 62.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KZN83666.1 - 1.1e-12 48.1 0.0 1.6e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KZN83666.1 - 8.1e-06 25.4 0.0 1.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 LZ_Tnp_IS66 PF13007.7 KZN83666.1 - 0.022 15.5 0.9 0.039 14.7 0.5 1.7 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain Oxidored_FMN PF00724.20 KZN83667.1 - 1.5e-62 211.9 0.0 1.7e-62 211.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Aldo_ket_red PF00248.21 KZN83668.1 - 8.3e-49 166.3 0.0 2.7e-48 164.7 0.0 1.8 2 0 0 2 2 2 1 Aldo/keto reductase family adh_short PF00106.25 KZN83668.1 - 4.3e-13 49.1 0.0 2.1e-07 30.6 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KZN83668.1 - 4e-07 29.8 0.0 0.00015 21.4 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN83668.1 - 0.0011 18.9 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 KR domain HTH_Tnp_1 PF01527.20 KZN83668.1 - 0.17 12.2 0.2 1.7 9.0 0.0 2.6 2 1 0 2 2 2 0 Transposase CHCH PF06747.13 KZN83670.1 - 1.1e-05 25.5 0.8 1.4e-05 25.0 0.8 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 KZN83670.1 - 0.026 14.8 2.6 0.065 13.5 2.6 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.13 KZN83670.1 - 0.034 14.5 3.5 2.1 8.8 0.3 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) CX9C PF16860.5 KZN83670.1 - 0.092 12.8 0.9 0.14 12.1 0.9 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NPR3 PF03666.13 KZN83671.1 - 1.1e-154 515.7 0.0 1.1e-154 515.7 0.0 2.4 3 0 0 3 3 3 1 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 KZN83671.1 - 0.11 11.3 0.0 0.32 9.7 0.0 1.7 2 0 0 2 2 2 0 Nitrogen permease regulator 2 Mago-bind PF09282.10 KZN83671.1 - 7.5 6.5 9.3 0.2 11.6 2.1 2.1 2 0 0 2 2 2 0 Mago binding La PF05383.17 KZN83672.1 - 3.3e-19 68.7 0.5 6.1e-19 67.8 0.5 1.4 1 0 0 1 1 1 1 La domain Band_7 PF01145.25 KZN83673.1 - 7e-31 107.6 1.0 1.3e-30 106.7 1.0 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 KZN83673.1 - 1e-22 79.9 0.6 3e-22 78.4 0.6 1.9 1 0 0 1 1 1 1 C-terminal region of band_7 Pox_A11 PF05061.13 KZN83673.1 - 0.026 13.8 0.2 0.04 13.2 0.2 1.3 1 0 0 1 1 1 0 Poxvirus A11 Protein Band_7_1 PF13421.6 KZN83673.1 - 0.057 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family HTH_5 PF01022.20 KZN83675.1 - 0.048 13.5 0.2 4.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Hira PF07569.11 KZN83678.1 - 1.6e-84 283.1 0.0 2.9e-84 282.2 0.0 1.5 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 KZN83678.1 - 2.2e-27 94.7 22.6 7e-05 23.5 0.0 8.8 7 1 1 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN83678.1 - 2.1e-14 53.6 0.1 0.019 15.3 0.0 6.2 3 1 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 KZN83678.1 - 2.4e-09 36.8 0.0 8.1e-09 35.1 0.0 2.0 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 KZN83678.1 - 0.00012 21.9 2.2 0.43 10.6 0.0 4.8 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KZN83678.1 - 0.0082 15.1 0.5 5 6.0 0.0 4.0 3 1 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 KZN83678.1 - 0.093 10.7 0.0 0.2 9.6 0.0 1.5 1 0 0 1 1 1 0 IKI3 family YchF-GTPase_C PF06071.13 KZN83679.1 - 7.8e-35 118.9 0.1 1.7e-34 117.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KZN83679.1 - 2.6e-16 59.7 0.0 6.1e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KZN83679.1 - 0.00072 19.1 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 KZN83679.1 - 0.0055 16.7 0.0 0.015 15.4 0.0 1.7 2 0 0 2 2 2 1 TGS domain AAA_14 PF13173.6 KZN83679.1 - 0.099 12.7 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Pre-PUA PF17832.1 KZN83680.1 - 1.4e-23 83.3 0.1 1.9e-23 82.9 0.1 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KZN83680.1 - 1e-13 51.0 0.1 1.4e-13 50.6 0.1 1.2 1 0 0 1 1 1 1 PUA domain DTHCT PF08070.11 KZN83682.1 - 2.3 9.0 22.9 0.053 14.2 9.4 2.9 1 1 1 2 2 2 0 DTHCT (NUC029) region GPI-anchored PF10342.9 KZN83683.1 - 1.3e-20 73.9 1.3 1.3e-20 73.9 1.3 2.8 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GREB1 PF15782.5 KZN83683.1 - 1.3 6.0 10.2 1.5 5.8 10.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Alpha-amylase PF00128.24 KZN83684.1 - 1.7e-23 83.8 0.0 3.5e-23 82.7 0.0 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 KZN83684.1 - 3.5e-05 22.2 0.1 0.27 9.4 0.0 3.0 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 Alpha-amylase PF00128.24 KZN83685.1 - 2.2e-47 162.3 0.8 3.1e-47 161.8 0.8 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KZN83685.1 - 1.7e-34 118.0 0.1 3e-34 117.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Alpha-amylase PF00128.24 KZN83686.1 - 3.1e-18 66.4 4.7 5.2e-18 65.7 0.4 2.9 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 KZN83686.1 - 8.9e-15 55.0 0.1 1.6e-14 54.2 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KZN83686.1 - 0.00017 21.1 0.0 0.00034 20.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KZN83686.1 - 0.09 12.8 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Ank_2 PF12796.7 KZN83687.1 - 2.9e-82 271.3 19.5 3.6e-12 46.7 0.2 9.0 2 2 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN83687.1 - 9.4e-70 230.2 6.0 5.4e-08 33.2 0.0 12.7 5 3 10 15 15 15 15 Ankyrin repeats (many copies) Ank_5 PF13857.6 KZN83687.1 - 2.6e-58 193.3 28.2 6.4e-08 32.7 0.1 11.8 5 2 9 14 14 14 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN83687.1 - 3.3e-58 186.8 7.2 0.0045 17.4 0.0 17.4 17 0 0 17 17 17 14 Ankyrin repeat Ank PF00023.30 KZN83687.1 - 4.1e-53 175.6 24.2 0.0078 16.6 0.0 17.3 17 0 0 17 17 17 16 Ankyrin repeat HET PF06985.11 KZN83687.1 - 5.6e-05 23.5 0.4 0.0043 17.4 0.0 2.8 1 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF1079 PF06435.11 KZN83687.1 - 0.029 14.5 6.2 1.4e+02 2.9 0.2 7.5 9 0 0 9 9 9 0 Repeat of unknown function (DUF1079) YjgF_endoribonc PF14588.6 KZN83687.1 - 0.099 12.8 0.4 55 3.9 0.0 4.0 2 1 0 3 3 3 0 YjgF/chorismate_mutase-like, putative endoribonuclease Dabb PF07876.12 KZN83687.1 - 0.23 12.1 1.3 1.9e+02 2.7 0.0 4.3 2 2 2 4 4 4 0 Stress responsive A/B Barrel Domain Dala_Dala_lig_C PF07478.13 KZN83689.1 - 2.9e-21 76.0 0.0 4.7e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KZN83689.1 - 0.002 18.2 0.0 0.0047 17.0 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 KZN83689.1 - 0.0033 17.0 0.0 0.0095 15.5 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KZN83689.1 - 0.025 14.3 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Phe_hydrox_dim PF07976.12 KZN83690.1 - 2e-40 138.5 0.0 3.4e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_3 PF01494.19 KZN83690.1 - 6.5e-32 111.1 0.0 9.2e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 KZN83690.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase FAD_binding_3 PF01494.19 KZN83691.1 - 6e-10 38.9 0.0 6.6e-10 38.8 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_12 PF01670.16 KZN83693.1 - 3.1e-78 262.7 11.9 3.5e-78 262.5 11.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 DUF5314 PF17241.2 KZN83694.1 - 0.00033 20.4 0.5 0.3 10.7 0.2 2.3 1 1 1 2 2 2 2 Family of unknown function (DUF5314) Retrotran_gag_2 PF14223.6 KZN83694.1 - 0.00082 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Fas_alpha_ACP PF18325.1 KZN83694.1 - 0.019 15.3 0.0 0.027 14.8 0.0 1.2 1 0 0 1 1 1 0 Fatty acid synthase subunit alpha Acyl carrier domain EST1 PF10374.9 KZN83694.1 - 0.17 12.5 0.6 0.48 11.1 0.6 1.9 1 1 0 1 1 1 0 Telomerase activating protein Est1 DUF4234 PF14018.6 KZN83695.1 - 0.073 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) LapA_dom PF06305.11 KZN83695.1 - 0.12 12.1 0.2 0.21 11.4 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain RNase_H PF00075.24 KZN83696.1 - 1.5e-17 64.1 0.0 2.4e-17 63.4 0.0 1.4 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 KZN83696.1 - 0.0019 18.0 0.0 0.068 13.0 0.0 2.2 1 1 0 1 1 1 1 Reverse transcriptase-like VPS9 PF02204.18 KZN83697.1 - 1.4e-17 63.8 0.0 3.5e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 KZN83697.1 - 2.6e-16 59.5 0.1 1.8e-12 47.2 0.0 4.7 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KZN83697.1 - 7.9e-13 48.8 0.0 8.2e-05 23.1 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) PX PF00787.24 KZN83697.1 - 6.5e-07 29.3 0.3 1.8e-06 27.9 0.3 1.8 1 0 0 1 1 1 1 PX domain Ank_4 PF13637.6 KZN83697.1 - 2e-06 28.2 0.0 0.066 13.8 0.0 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KZN83697.1 - 2.8e-05 24.4 0.2 1.9 9.1 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KZN83697.1 - 0.001 19.4 0.1 34 5.4 0.0 5.5 5 0 0 5 5 5 0 Ankyrin repeat Ribosomal_S11 PF00411.19 KZN83698.1 - 4.7e-06 27.0 0.0 9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S11 Tim44 PF04280.15 KZN83699.1 - 6.3e-37 126.9 0.0 2.3e-36 125.1 0.0 1.9 2 0 0 2 2 2 1 Tim44-like domain FHIPEP PF00771.20 KZN83699.1 - 0.056 11.9 0.0 0.086 11.3 0.0 1.3 1 0 0 1 1 1 0 FHIPEP family MFS_1 PF07690.16 KZN83700.1 - 7e-28 97.6 21.3 1.6e-27 96.4 21.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily CN_hydrolase PF00795.22 KZN83700.1 - 3e-25 89.0 0.0 6.2e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Band_7_C PF16200.5 KZN83700.1 - 0.13 12.3 0.0 0.77 9.9 0.0 2.1 2 0 0 2 2 2 0 C-terminal region of band_7 Caveolin PF01146.17 KZN83700.1 - 4.3 7.3 5.8 0.64 10.0 0.6 2.3 2 0 0 2 2 2 0 Caveolin FAD_binding_3 PF01494.19 KZN83701.1 - 3e-13 49.7 1.2 2.3e-07 30.4 1.3 3.1 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KZN83701.1 - 0.0036 17.5 0.0 0.0079 16.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KZN83701.1 - 0.029 13.9 0.0 0.057 13.0 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF3420 PF11900.8 KZN83701.1 - 0.068 13.3 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3420) Abhydrolase_3 PF07859.13 KZN83702.1 - 1.8e-50 171.8 0.0 2.5e-50 171.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KZN83702.1 - 2.9e-06 26.4 0.3 1.1e-05 24.5 0.3 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KZN83702.1 - 0.00016 21.2 0.0 0.11 12.0 0.0 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.12 KZN83702.1 - 0.00023 19.9 0.0 0.02 13.6 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Epimerase PF01370.21 KZN83703.1 - 9.4e-14 51.4 0.1 2e-13 50.4 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KZN83703.1 - 6.8e-12 45.0 0.0 1e-11 44.4 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KZN83703.1 - 3e-11 43.0 0.0 2.9e-10 39.8 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KZN83703.1 - 1.3e-09 38.3 0.0 2.1e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KZN83703.1 - 4e-08 33.0 0.0 6.5e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KZN83703.1 - 0.00012 21.3 0.0 0.00024 20.4 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KZN83703.1 - 0.00039 20.0 0.1 0.00061 19.4 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 KZN83703.1 - 0.0029 17.5 0.2 0.0068 16.3 0.1 1.6 2 0 0 2 2 2 1 KR domain RmlD_sub_bind PF04321.17 KZN83703.1 - 0.059 12.5 0.2 0.099 11.7 0.2 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain MFS_1 PF07690.16 KZN83704.1 - 2.3e-34 118.9 34.3 3.1e-34 118.5 34.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KZN83704.1 - 7.7e-08 32.0 2.8 7.7e-08 32.0 2.8 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB LcrV PF04792.12 KZN83704.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 V antigen (LcrV) protein FAD_binding_3 PF01494.19 KZN83705.1 - 1.1e-23 84.1 0.0 1.4e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KZN83705.1 - 3e-08 33.8 2.7 3.2e-08 33.7 1.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KZN83705.1 - 1.4e-06 28.2 1.1 3.2e-06 27.0 1.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KZN83705.1 - 1.8e-05 24.3 0.1 2.4e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KZN83705.1 - 5.8e-05 22.5 2.8 0.00012 21.5 0.9 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KZN83705.1 - 6.8e-05 22.1 4.2 0.00012 21.3 4.1 1.4 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KZN83705.1 - 0.00018 20.7 0.0 0.00028 20.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 KZN83705.1 - 0.0011 19.4 0.3 0.003 18.1 0.3 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KZN83705.1 - 0.0018 17.4 0.7 0.0026 16.9 0.7 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 KZN83705.1 - 0.0048 15.8 0.1 0.027 13.3 0.1 2.1 2 1 1 3 3 3 1 Tryptophan halogenase HI0933_like PF03486.14 KZN83705.1 - 0.0077 15.0 1.1 0.0077 15.0 1.1 1.5 2 0 0 2 2 2 1 HI0933-like protein Rossmann-like PF10727.9 KZN83705.1 - 0.015 15.2 1.1 0.034 14.0 1.0 1.7 1 1 0 1 1 1 0 Rossmann-like domain Amino_oxidase PF01593.24 KZN83705.1 - 0.017 14.5 0.5 0.029 13.7 0.5 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KZN83705.1 - 0.032 13.5 0.2 0.064 12.5 0.1 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KZN83705.1 - 0.042 13.1 0.3 0.071 12.4 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KZN83705.1 - 0.047 13.7 0.5 0.2 11.7 0.3 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 KZN83705.1 - 0.11 11.7 0.1 0.33 10.2 0.1 1.7 2 0 0 2 2 2 0 Thi4 family NAD_Gly3P_dh_N PF01210.23 KZN83705.1 - 0.14 12.1 0.1 0.24 11.4 0.1 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Fungal_trans_2 PF11951.8 KZN83706.1 - 1.7e-49 168.7 5.2 2.3e-49 168.2 5.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN83706.1 - 7.6e-11 42.0 36.1 3.4e-05 23.9 16.0 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC2_membrane PF01061.24 KZN83707.1 - 1.4e-58 197.8 58.7 4e-34 117.9 15.3 3.6 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KZN83707.1 - 9.7e-39 133.0 0.0 3.4e-18 66.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KZN83707.1 - 3.5e-22 78.1 12.9 4.8e-21 74.5 0.1 3.6 4 0 0 4 4 3 2 CDR ABC transporter AAA_21 PF13304.6 KZN83707.1 - 7.8e-07 29.2 0.2 0.011 15.6 0.0 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KZN83707.1 - 9.4e-06 25.6 0.2 0.00022 21.2 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KZN83707.1 - 3.8e-05 24.1 0.1 0.02 15.3 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KZN83707.1 - 0.00036 20.8 0.6 0.39 11.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KZN83707.1 - 0.00052 19.7 0.6 0.016 14.9 0.2 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KZN83707.1 - 0.0013 18.8 0.0 0.37 10.9 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.6 KZN83707.1 - 0.0054 16.3 0.1 0.16 11.6 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KZN83707.1 - 0.014 15.9 0.0 1.3 9.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 KZN83707.1 - 0.025 14.3 0.2 4.4 7.0 0.2 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KZN83707.1 - 0.092 12.2 0.0 18 4.7 0.0 2.9 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain Com_YlbF PF06133.11 KZN83707.1 - 0.12 13.0 0.4 0.27 11.9 0.4 1.5 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA Zeta_toxin PF06414.12 KZN83707.1 - 0.17 11.1 0.3 20 4.4 0.1 3.0 3 0 0 3 3 3 0 Zeta toxin AAA_23 PF13476.6 KZN83707.1 - 0.38 11.2 1.3 0.58 10.6 0.1 1.8 2 0 0 2 2 2 0 AAA domain Fungal_trans PF04082.18 KZN83708.1 - 3.6e-14 52.4 0.0 5.3e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN83708.1 - 1.1e-08 35.1 10.0 2.1e-08 34.2 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SGTA_dimer PF16546.5 KZN83709.1 - 2.6e-25 88.0 0.2 4.8e-25 87.1 0.2 1.5 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 KZN83709.1 - 1.8e-15 56.0 7.7 3e-06 26.8 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KZN83709.1 - 2.8e-14 52.0 10.8 3e-05 23.8 0.3 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KZN83709.1 - 3.9e-11 42.3 9.3 8.8e-06 25.5 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KZN83709.1 - 1.8e-09 37.1 9.1 5e-08 32.5 0.8 3.1 1 1 2 3 3 3 3 TPR repeat TPR_16 PF13432.6 KZN83709.1 - 1.7e-07 31.7 10.2 6.2e-05 23.6 6.4 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KZN83709.1 - 1.1e-06 28.6 2.1 0.015 15.7 0.2 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KZN83709.1 - 1.8e-06 27.6 1.1 0.076 13.1 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KZN83709.1 - 2.1e-06 27.9 6.4 0.0016 18.7 2.5 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KZN83709.1 - 2.1e-05 24.9 7.9 0.012 16.1 4.6 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat STI1 PF17830.1 KZN83709.1 - 0.00018 21.3 8.8 0.0013 18.6 3.9 2.9 3 0 0 3 3 3 1 STI1 domain TPR_14 PF13428.6 KZN83709.1 - 0.00067 20.3 11.1 0.89 10.6 2.4 3.7 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 KZN83709.1 - 0.0015 18.6 3.0 0.012 15.7 1.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat XPC-binding PF09280.11 KZN83709.1 - 0.0026 17.5 1.6 0.0058 16.3 1.6 1.6 1 0 0 1 1 1 1 XPC-binding domain TPR_6 PF13174.6 KZN83709.1 - 0.032 14.9 7.1 0.31 11.8 0.2 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat BTAD PF03704.17 KZN83709.1 - 0.045 14.2 3.7 0.11 12.9 1.1 2.2 2 0 0 2 2 2 0 Bacterial transcriptional activator domain MIT PF04212.18 KZN83709.1 - 0.14 12.2 2.0 2.9 8.0 0.5 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 KZN83709.1 - 1 9.3 8.6 14 5.7 0.8 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat RIC1 PF07064.13 KZN83710.1 - 9.1e-86 287.4 0.1 1.4e-85 286.7 0.1 1.3 1 0 0 1 1 1 1 RIC1 Aldedh PF00171.22 KZN83711.1 - 4.3e-106 355.2 0.0 5.1e-106 354.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aconitase PF00330.20 KZN83714.1 - 1.5e-112 377.0 0.0 2.6e-62 211.3 0.0 2.4 3 0 0 3 3 3 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KZN83714.1 - 2.9e-35 121.4 0.0 5.2e-35 120.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 KZN83714.1 - 0.14 10.8 0.0 0.24 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF521) RraA-like PF03737.15 KZN83715.1 - 1.4e-35 122.6 0.0 1.8e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA DUF4939 PF16297.5 KZN83717.1 - 0.034 14.0 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Bac_luciferase PF00296.20 KZN83718.1 - 4.9e-69 233.2 0.0 5.8e-69 232.9 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF2961 PF11175.8 KZN83719.1 - 3.5e-85 285.4 5.5 4.5e-85 285.0 5.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2961) Glyco_hydro_32N PF00251.20 KZN83721.1 - 7.5e-49 166.9 0.0 1.1e-48 166.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KZN83721.1 - 2e-23 83.1 0.0 2.8e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR_2 PF13088.6 KZN83721.1 - 0.025 13.9 0.2 2.9 7.1 0.0 2.3 1 1 0 2 2 2 0 BNR repeat-like domain BNR PF02012.20 KZN83721.1 - 0.091 12.8 3.9 0.4 10.9 0.1 2.8 2 0 0 2 2 2 0 BNR/Asp-box repeat Sugar_tr PF00083.24 KZN83722.1 - 9.4e-74 248.9 23.6 1.2e-73 248.6 23.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN83722.1 - 1.2e-18 67.2 25.0 1.2e-18 67.2 25.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KZN83722.1 - 1.9e-07 29.9 2.2 3.4e-07 29.1 2.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATP-synt_G PF04718.15 KZN83722.1 - 0.16 12.8 0.2 1 10.2 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial ATP synthase g subunit Inhibitor_I78 PF11720.8 KZN83723.1 - 4.6e-12 45.8 0.0 5.9e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 KZN83723.1 - 0.0026 18.4 0.0 0.0041 17.8 0.0 1.4 1 0 0 1 1 1 1 Potato inhibitor I family Alpha-L-AF_C PF06964.12 KZN83724.1 - 1.4e-31 109.9 0.1 2e-31 109.4 0.1 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Sugar_tr PF00083.24 KZN83725.1 - 8.2e-106 354.6 17.3 9.4e-106 354.4 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN83725.1 - 2.7e-34 118.6 21.2 4.8e-25 88.2 2.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LapA_dom PF06305.11 KZN83725.1 - 1.2 8.9 0.0 1.2 8.9 0.0 4.3 4 1 1 5 5 5 0 Lipopolysaccharide assembly protein A domain Nefa_Nip30_N PF10187.9 KZN83726.1 - 4.8e-31 107.2 15.6 4.8e-31 107.2 15.6 2.3 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.13 KZN83726.1 - 0.031 13.9 21.9 0.039 13.6 21.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) PI3K_1B_p101 PF10486.9 KZN83726.1 - 0.39 8.5 8.1 0.43 8.3 8.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Aldo_ket_red PF00248.21 KZN83727.1 - 4.8e-44 150.7 0.0 3e-42 144.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_6 PF01341.17 KZN83729.1 - 5.2e-108 361.4 2.3 6.5e-108 361.1 2.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CK_II_beta PF01214.18 KZN83730.1 - 7.2e-76 254.1 0.1 1.1e-75 253.5 0.1 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Plant_vir_prot PF01307.17 KZN83730.1 - 0.016 15.4 0.1 0.039 14.2 0.1 1.6 1 0 0 1 1 1 0 Plant viral movement protein CxC5 PF18718.1 KZN83730.1 - 0.02 14.9 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases Abhydrolase_6 PF12697.7 KZN83731.1 - 1.7e-06 28.8 2.2 2.1e-06 28.5 2.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KZN83731.1 - 0.0034 17.3 0.1 0.054 13.3 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KZN83731.1 - 0.0084 15.8 0.0 0.019 14.6 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KZN83731.1 - 0.081 12.2 0.1 0.58 9.4 0.1 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 KZN83731.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Thioesterase PF00975.20 KZN83731.1 - 0.11 12.6 0.1 0.24 11.5 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain C_GCAxxG_C_C PF09719.10 KZN83731.1 - 0.21 11.9 0.1 0.35 11.1 0.1 1.3 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) JAB PF01398.21 KZN83732.1 - 1.4e-09 37.9 0.5 5.1e-08 32.9 0.5 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Lactamase_B PF00753.27 KZN83734.1 - 4.7e-18 65.9 1.9 1e-17 64.8 1.9 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KZN83734.1 - 3.9e-05 23.3 0.1 7.2e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Pyr_redox_2 PF07992.14 KZN83735.1 - 1.5e-10 40.8 0.0 5.3e-07 29.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KZN83735.1 - 0.011 15.3 0.1 0.017 14.7 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KZN83735.1 - 0.052 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Kelch_1 PF01344.25 KZN83735.1 - 0.12 12.0 0.1 4.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Kelch motif Lycopene_cycl PF05834.12 KZN83735.1 - 0.18 10.8 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Mito_carr PF00153.27 KZN83736.1 - 5.4e-41 138.4 4.4 7.9e-17 61.0 0.3 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein YiaAB PF05360.14 KZN83737.1 - 0.042 14.1 0.8 0.064 13.5 0.8 1.3 1 0 0 1 1 1 0 yiaA/B two helix domain Dynamin_N PF00350.23 KZN83739.1 - 8.3e-28 97.5 1.2 3.1e-15 56.6 0.2 2.8 2 1 1 3 3 3 2 Dynamin family Dynamin_M PF01031.20 KZN83739.1 - 3e-19 69.3 0.0 2.6e-13 49.8 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 KZN83739.1 - 9.5e-05 22.5 0.0 0.0003 20.8 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 KZN83739.1 - 0.00067 19.8 0.7 0.012 15.7 0.0 3.1 3 0 0 3 3 3 1 Dynamin GTPase effector domain AAA_15 PF13175.6 KZN83739.1 - 0.015 15.0 0.1 0.058 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AIG1 PF04548.16 KZN83739.1 - 0.015 14.6 0.2 0.23 10.7 0.1 2.7 2 1 0 2 2 2 0 AIG1 family AAA_16 PF13191.6 KZN83739.1 - 0.022 15.1 0.1 0.19 12.1 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain FeoB_N PF02421.18 KZN83739.1 - 0.027 14.0 0.6 3.1 7.3 0.0 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B Ras PF00071.22 KZN83739.1 - 0.03 13.9 0.0 0.081 12.5 0.0 1.7 1 0 0 1 1 1 0 Ras family Roc PF08477.13 KZN83739.1 - 0.12 12.5 0.0 0.46 10.7 0.0 2.0 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF3134 PF11332.8 KZN83740.1 - 0.022 15.1 0.2 0.035 14.4 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3134) Mito_fiss_reg PF05308.11 KZN83741.1 - 0.29 11.2 0.0 0.29 11.2 0.0 13.5 6 3 8 15 15 15 0 Mitochondrial fission regulator HMG_box_2 PF09011.10 KZN83742.1 - 3.5e-05 24.3 8.5 7.9e-05 23.2 0.4 3.3 3 1 0 3 3 3 2 HMG-box domain HMG_box PF00505.19 KZN83742.1 - 0.0022 18.4 1.5 0.0022 18.4 1.5 3.2 2 2 0 2 2 2 1 HMG (high mobility group) box HMG_box_5 PF14887.6 KZN83742.1 - 0.0097 15.9 0.2 0.028 14.4 0.0 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box 5 DEAD PF00270.29 KZN83743.1 - 3.1e-48 163.8 0.0 4e-47 160.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KZN83743.1 - 9.3e-27 93.6 0.0 2.9e-26 92.0 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain MFMR_assoc PF16596.5 KZN83744.1 - 0.047 14.2 3.5 0.067 13.6 3.5 1.3 1 0 0 1 1 1 0 Disordered region downstream of MFMR zf-C2H2 PF00096.26 KZN83745.1 - 1.4e-22 78.8 42.3 5.4e-06 26.6 4.4 8.3 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KZN83745.1 - 4e-16 58.6 36.7 3.2e-07 30.5 2.2 7.3 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 KZN83745.1 - 3.9e-10 39.7 53.7 0.00027 21.5 3.0 9.0 8 0 0 8 8 8 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KZN83745.1 - 4.9e-05 23.5 3.2 0.0026 18.0 0.1 5.6 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KZN83745.1 - 0.00037 20.8 24.2 0.0063 16.9 0.1 5.9 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KZN83745.1 - 0.051 13.6 0.4 0.051 13.6 0.4 5.7 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KZN83745.1 - 0.69 9.7 23.8 2.8 7.8 0.1 5.3 5 0 0 5 5 5 0 zinc-finger C2H2-type Spc7 PF08317.11 KZN83746.1 - 0.072 12.0 1.4 0.098 11.5 1.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein PapG_C PF03628.13 KZN83746.1 - 0.16 11.8 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 PapG chaperone-binding domain Podoplanin PF05808.11 KZN83747.1 - 8.5e-06 26.0 1.7 1.4e-05 25.3 1.7 1.2 1 0 0 1 1 1 1 Podoplanin PTP_tm PF18861.1 KZN83747.1 - 0.00021 21.4 0.0 0.00038 20.5 0.0 1.4 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J Glycophorin_A PF01102.18 KZN83747.1 - 0.0032 17.7 1.1 0.0055 16.9 1.1 1.5 1 0 0 1 1 1 1 Glycophorin A BatD PF13584.6 KZN83747.1 - 0.012 14.4 0.1 0.016 14.0 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance SKG6 PF08693.10 KZN83747.1 - 0.025 14.0 1.9 0.025 14.0 1.9 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 KZN83747.1 - 0.033 15.1 0.0 0.064 14.1 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KZN83747.1 - 0.034 14.0 0.3 0.049 13.5 0.3 1.3 1 0 0 1 1 1 0 TMEM154 protein family Phage_Coat_B PF05356.11 KZN83747.1 - 0.05 13.5 2.9 0.1 12.5 2.8 1.6 1 1 0 1 1 1 0 Phage Coat protein B DUF1180 PF06679.12 KZN83747.1 - 0.058 13.8 3.7 0.084 13.3 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) VSP PF03302.13 KZN83747.1 - 0.073 11.9 8.1 0.22 10.4 8.1 1.6 1 1 0 1 1 1 0 Giardia variant-specific surface protein DUF4366 PF14283.6 KZN83747.1 - 0.073 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF5305 PF17231.2 KZN83747.1 - 0.11 11.9 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Syndecan PF01034.20 KZN83747.1 - 0.15 12.0 0.2 0.28 11.1 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain Gram_pos_anchor PF00746.21 KZN83747.1 - 0.26 11.2 0.6 0.5 10.3 0.6 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif MGC-24 PF05283.11 KZN83747.1 - 0.96 9.9 16.3 1.1 9.8 14.3 2.2 2 1 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Med3 PF11593.8 KZN83747.1 - 0.96 8.6 10.9 1.2 8.2 10.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal polyprenyl_synt PF00348.17 KZN83748.1 - 6.3e-14 51.6 0.0 6.8e-14 51.5 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase DUF4974 PF16344.5 KZN83748.1 - 0.038 14.0 0.0 0.054 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4974) Pkinase_fungal PF17667.1 KZN83749.1 - 3.5e-83 279.7 0.0 5.3e-41 140.7 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KZN83749.1 - 7e-06 25.6 0.0 1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KZN83749.1 - 0.053 13.4 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 KZN83751.1 - 9.5e-09 35.0 0.0 2.2e-08 33.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN83751.1 - 6.2e-06 25.7 0.0 9.4e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KZN83751.1 - 5e-05 23.4 0.1 0.0001 22.4 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN83751.1 - 0.012 15.2 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 KZN83751.1 - 0.02 13.7 0.0 0.027 13.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase CrtC PF07143.11 KZN83752.1 - 0.0032 18.2 0.0 0.03 15.0 0.0 2.1 2 0 0 2 2 2 1 CrtC N-terminal lipocalin domain Lipocalin_9 PF17186.4 KZN83752.1 - 0.0099 16.2 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 1 Lipocalin-like domain Sulfotransfer_4 PF17784.1 KZN83753.1 - 8.2e-36 123.9 1.5 2.1e-24 86.6 0.2 2.1 1 1 1 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KZN83753.1 - 0.002 18.6 2.5 0.072 13.5 0.3 2.7 1 1 1 2 2 2 2 Sulfotransferase family DUF2985 PF11204.8 KZN83755.1 - 6e-14 52.0 0.7 1e-13 51.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) DnaB_2 PF07261.11 KZN83758.1 - 0.035 13.8 0.0 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Replication initiation and membrane attachment Sugar_tr PF00083.24 KZN83759.1 - 6.8e-92 308.7 24.4 8e-92 308.5 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN83759.1 - 2e-29 102.6 61.8 4.6e-27 94.9 32.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KZN83759.1 - 0.00013 20.4 18.3 0.00028 19.3 0.4 3.3 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family YqhR PF11085.8 KZN83759.1 - 0.013 15.5 0.6 0.1 12.5 0.3 2.4 2 0 0 2 2 2 0 Conserved membrane protein YqhR DUF4149 PF13664.6 KZN83759.1 - 1.4 9.2 11.0 3.2 8.1 0.3 4.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4149) DUF2781 PF10914.8 KZN83759.1 - 4.1 7.8 6.4 2.4 8.6 1.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2781) ADH_zinc_N PF00107.26 KZN83761.1 - 1.8e-06 28.0 0.0 4e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Sugar_tr PF00083.24 KZN83762.1 - 7.3e-82 275.6 18.6 8.7e-82 275.4 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN83762.1 - 1.9e-22 79.7 24.0 1.9e-22 79.7 24.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3980 PF13140.6 KZN83762.1 - 0.17 12.3 2.2 0.65 10.5 2.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3980) MFS_1_like PF12832.7 KZN83762.1 - 0.53 9.1 11.3 0.024 13.5 5.2 1.7 2 0 0 2 2 2 0 MFS_1 like family Fungal_trans PF04082.18 KZN83763.1 - 1.5e-09 37.3 2.9 1.1e-08 34.4 2.8 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KZN83763.1 - 1e-08 35.1 10.7 5.5e-05 23.4 1.3 3.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KZN83763.1 - 6e-08 32.8 2.1 6e-08 32.8 2.1 3.4 3 0 0 3 3 3 1 Zinc-finger double domain Zn_clus PF00172.18 KZN83763.1 - 0.00015 21.8 11.6 0.00015 21.8 11.6 1.9 2 0 0 2 2 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_11 PF16622.5 KZN83763.1 - 0.00091 18.9 7.2 0.17 11.7 0.4 3.4 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-met PF12874.7 KZN83763.1 - 0.0012 19.2 0.4 0.0012 19.2 0.4 2.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KZN83763.1 - 0.0013 19.4 16.2 0.0026 18.5 0.8 3.6 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KZN83763.1 - 0.016 15.2 15.5 0.054 13.5 2.2 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KZN83763.1 - 0.066 13.5 5.2 0.33 11.3 0.8 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 KZN83763.1 - 0.71 9.6 3.4 0.49 10.1 0.4 2.2 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-LYAR PF08790.11 KZN83763.1 - 1.2 9.1 3.8 1.1 9.2 0.4 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2HE PF16278.5 KZN83763.1 - 5 7.7 5.9 28 5.3 6.0 2.2 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger Glyco_hydro_31 PF01055.26 KZN83764.1 - 1e-115 387.4 6.5 1.5e-115 386.9 6.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KZN83764.1 - 0.00054 20.2 2.2 0.001 19.4 0.1 2.6 2 1 0 2 2 2 1 Galactose mutarotase-like DUF4968 PF16338.5 KZN83764.1 - 0.012 15.9 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4968) DUF4826 PF16108.5 KZN83764.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4826) Glyco_hydro_39 PF01229.17 KZN83766.1 - 0.0037 15.9 0.1 0.0051 15.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Acetyltransf_3 PF13302.7 KZN83769.1 - 3.4e-14 53.7 0.0 3.9e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KZN83769.1 - 0.0012 19.0 0.0 0.0017 18.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family adh_short PF00106.25 KZN83770.1 - 4e-38 130.9 0.0 5.3e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN83770.1 - 2.4e-36 125.5 0.1 3e-32 112.0 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN83770.1 - 4.9e-14 52.6 0.0 2.5e-13 50.3 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KZN83770.1 - 9.4e-05 22.0 0.0 0.00067 19.2 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Beta-lactamase PF00144.24 KZN83771.1 - 2.4e-27 96.1 0.0 4.1e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase Lactamase_B PF00753.27 KZN83772.1 - 9.9e-12 45.3 0.2 1.6e-11 44.6 0.2 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KZN83772.1 - 0.00025 20.6 0.1 0.00074 19.1 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KZN83772.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Pkinase PF00069.25 KZN83774.1 - 4e-36 124.7 0.0 1e-35 123.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN83774.1 - 2.9e-18 66.1 0.0 4.6e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KZN83774.1 - 0.002 17.5 0.0 1 8.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KZN83774.1 - 0.012 14.4 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase FHA PF00498.26 KZN83774.1 - 0.036 14.4 0.0 0.09 13.1 0.0 1.7 1 0 0 1 1 1 0 FHA domain FTA2 PF13095.6 KZN83774.1 - 0.037 13.6 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 UPF0261 PF06792.11 KZN83775.1 - 2.9e-158 527.1 0.7 3.2e-158 526.9 0.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) DUF5429 PF17494.2 KZN83775.1 - 0.067 13.2 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5429) AdoHcyase PF05221.17 KZN83776.1 - 2.3e-129 430.8 0.0 3.4e-73 246.4 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KZN83776.1 - 2.6e-80 268.2 2.8 4.4e-80 267.4 2.8 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KZN83776.1 - 5e-06 26.0 0.2 9.8e-06 25.0 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KZN83776.1 - 0.004 16.7 0.4 0.0073 15.9 0.4 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KZN83776.1 - 0.006 16.8 0.1 0.013 15.8 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain Oxidored_nitro PF00148.19 KZN83776.1 - 0.02 13.7 0.1 0.18 10.5 0.0 2.2 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase ELFV_dehydrog PF00208.21 KZN83776.1 - 0.022 14.5 0.1 0.037 13.7 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Urocanase PF01175.18 KZN83776.1 - 0.11 12.2 0.3 0.19 11.3 0.3 1.4 1 0 0 1 1 1 0 Urocanase Rossmann-like domain HMG-CoA_red PF00368.18 KZN83778.1 - 6.7e-89 298.5 0.1 8.1e-89 298.2 0.1 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase RVT_2 PF07727.14 KZN83781.1 - 9.1e-22 77.9 0.0 1.3e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KZN83781.1 - 1.3e-08 35.1 0.0 3.4e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain PH_14 PF17787.1 KZN83782.1 - 0.0032 17.3 0.0 0.0066 16.3 0.0 1.5 1 0 0 1 1 1 1 PH domain Retrotran_gag_2 PF14223.6 KZN83782.1 - 0.063 12.9 2.0 0.11 12.1 2.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Use1 PF09753.9 KZN83782.1 - 2.2 7.9 8.5 14 5.3 8.5 2.0 1 1 0 1 1 1 0 Membrane fusion protein Use1 Acyl-CoA_dh_1 PF00441.24 KZN83783.1 - 1.5e-05 25.2 0.1 5.1e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain zf-C2H2 PF00096.26 KZN83784.1 - 3.6e-08 33.4 8.5 2.8e-06 27.5 0.9 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KZN83784.1 - 2.7e-05 24.4 0.6 2.7e-05 24.4 0.6 4.1 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KZN83784.1 - 8.5e-05 23.1 6.0 0.00017 22.1 0.3 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.12 KZN83784.1 - 0.00017 21.8 3.7 0.00029 21.1 3.7 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KZN83784.1 - 0.0011 19.3 7.8 0.0022 18.3 0.2 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KZN83784.1 - 0.0037 17.5 0.5 0.0091 16.3 0.5 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF2225 PF09986.9 KZN83784.1 - 0.0039 16.9 0.3 0.0063 16.3 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_6 PF13912.6 KZN83784.1 - 0.018 15.0 0.1 0.051 13.6 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger DUF1178 PF06676.11 KZN83784.1 - 0.03 14.7 0.3 0.059 13.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) zf-H2C2_5 PF13909.6 KZN83784.1 - 0.043 13.6 0.2 0.043 13.6 0.2 3.0 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KZN83784.1 - 0.13 12.7 0.9 0.21 11.9 0.9 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KZN83784.1 - 0.14 12.1 0.3 0.24 11.3 0.3 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) zf-BED PF02892.15 KZN83784.1 - 0.16 12.0 3.7 0.31 11.1 3.7 1.5 1 0 0 1 1 1 0 BED zinc finger Kelch_6 PF13964.6 KZN83787.1 - 0.0019 18.4 2.5 0.98 9.8 0.0 3.8 3 1 0 3 3 3 2 Kelch motif Glycophorin_A PF01102.18 KZN83787.1 - 0.004 17.4 0.9 0.013 15.7 0.9 1.8 1 1 0 1 1 1 1 Glycophorin A TMEM154 PF15102.6 KZN83787.1 - 0.02 14.8 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family Kelch_3 PF13415.6 KZN83787.1 - 0.024 14.9 0.1 0.024 14.9 0.1 4.7 5 1 1 6 6 6 0 Galactose oxidase, central domain MGC-24 PF05283.11 KZN83787.1 - 0.09 13.2 3.0 0.19 12.2 1.0 2.5 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Mid2 PF04478.12 KZN83787.1 - 0.1 12.4 1.1 0.22 11.4 1.1 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor HAT PF02184.16 KZN83788.1 - 2.5e-18 65.7 78.4 2.8e-14 52.8 5.1 13.2 15 0 0 15 15 15 4 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 KZN83788.1 - 2.1e-17 62.3 29.4 0.00012 22.6 0.2 10.9 8 3 6 14 14 13 7 Tetratricopeptide repeat TPR_19 PF14559.6 KZN83788.1 - 3e-15 56.5 4.1 2.3e-06 28.0 0.0 6.3 8 0 0 8 8 6 3 Tetratricopeptide repeat Suf PF05843.14 KZN83788.1 - 2.2e-14 54.1 21.5 0.00051 20.1 0.4 6.4 2 2 4 6 6 6 4 Suppressor of forked protein (Suf) TPR_17 PF13431.6 KZN83788.1 - 3.1e-11 42.8 3.3 0.16 12.4 0.0 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_15 PF13429.6 KZN83788.1 - 3.1e-05 23.3 17.8 0.4 9.8 0.4 6.2 2 1 3 6 6 6 4 Tetratricopeptide repeat NRDE-2 PF08424.10 KZN83788.1 - 0.00025 20.3 26.3 0.03 13.5 7.2 5.0 3 2 2 5 5 5 4 NRDE-2, necessary for RNA interference TPR_8 PF13181.6 KZN83788.1 - 0.00031 20.7 12.8 23 5.5 0.0 7.7 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 KZN83788.1 - 0.00099 19.0 19.6 0.18 12.0 0.0 7.8 10 0 0 10 10 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 KZN83788.1 - 0.0025 17.6 2.2 8.6 6.4 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KZN83788.1 - 0.017 15.8 12.1 4.4 8.0 0.0 6.2 7 1 1 8 8 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 KZN83788.1 - 0.067 13.9 16.2 11 6.9 0.0 7.5 8 0 0 8 8 8 0 Tetratricopeptide repeat QIL1 PF15884.5 KZN83788.1 - 0.21 12.2 0.9 2.9 8.6 0.0 3.4 4 0 0 4 4 2 0 MICOS complex subunit MIC13, QIL1 TPR_9 PF13371.6 KZN83788.1 - 0.26 11.5 8.4 11 6.3 0.1 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KZN83788.1 - 0.37 10.9 6.5 31 4.8 1.0 4.9 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 KZN83788.1 - 3.7 7.9 17.6 7 7.0 0.1 6.5 8 1 0 8 8 6 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 KZN83788.1 - 9.6 6.4 28.0 0.054 13.6 1.1 6.7 7 2 2 9 9 9 0 U3 small nucleolar RNA-associated protein 6 Nop PF01798.18 KZN83789.1 - 1.2e-60 204.8 0.0 1.6e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KZN83789.1 - 5.8e-46 156.3 0.3 1.8e-45 154.8 0.3 1.9 1 1 0 1 1 1 1 Prp31 C terminal domain MFS_1 PF07690.16 KZN83791.1 - 5e-29 101.3 55.8 3.9e-28 98.4 55.8 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN83791.1 - 2.6e-06 26.6 16.2 2.6e-06 26.6 16.2 3.3 2 1 0 3 3 3 1 Sugar (and other) transporter SAMP PF05924.11 KZN83792.1 - 0.24 10.8 1.3 1.6 8.1 0.1 2.5 2 0 0 2 2 2 0 SAMP Motif PS-DH PF14765.6 KZN83793.1 - 7.6e-72 242.1 0.0 1.3e-71 241.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 KZN83793.1 - 6.4e-62 209.4 0.0 1.4e-61 208.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KZN83793.1 - 1.5e-51 174.9 0.5 1.2e-50 171.9 0.0 2.5 2 1 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 KZN83793.1 - 4e-50 171.1 0.0 7.3e-50 170.3 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KZN83793.1 - 2.8e-32 111.2 0.0 6.9e-32 109.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KZN83793.1 - 8.7e-16 58.4 1.0 1.4e-09 38.3 0.0 2.8 2 0 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 KZN83793.1 - 2.7e-11 43.5 0.1 5.2e-10 39.4 0.1 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KZN83793.1 - 5.5e-11 43.6 0.0 2.5e-08 35.0 0.0 3.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 KZN83793.1 - 4.6e-08 33.3 0.2 2.5e-07 30.9 0.0 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site Collagen PF01391.18 KZN83793.1 - 6.7e-08 32.2 14.1 1.6e-07 31.0 14.1 1.5 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) adh_short PF00106.25 KZN83793.1 - 3.2e-06 26.7 0.1 0.0034 16.9 0.0 2.6 2 0 0 2 2 2 2 short chain dehydrogenase Thiolase_N PF00108.23 KZN83793.1 - 0.00084 18.8 0.1 0.0026 17.2 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KZN83793.1 - 0.00093 19.0 1.0 0.0047 16.7 0.2 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_12 PF08242.12 KZN83793.1 - 0.0011 19.6 0.0 0.022 15.5 0.0 3.0 3 0 0 3 3 2 1 Methyltransferase domain ADH_N PF08240.12 KZN83793.1 - 0.0018 18.1 0.0 0.0045 16.9 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 3Beta_HSD PF01073.19 KZN83793.1 - 0.025 13.6 0.0 0.053 12.5 0.0 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Fungal_trans PF04082.18 KZN83794.1 - 8.2e-08 31.6 0.9 1.5e-07 30.7 0.1 1.8 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN83794.1 - 0.0055 16.8 5.1 0.014 15.5 5.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KZN83795.1 - 4.7e-50 170.7 0.0 1.3e-33 116.5 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 PhyH PF05721.13 KZN83796.1 - 1.3e-07 32.1 0.0 5.9e-07 30.0 0.0 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Aldo_ket_red PF00248.21 KZN83798.1 - 4.3e-66 223.1 0.0 4.8e-66 222.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Phage_TAC_10 PF10963.8 KZN83798.1 - 0.13 12.4 0.0 0.36 11.0 0.0 1.7 1 0 0 1 1 1 0 Phage tail assembly chaperone zf-H2C2_2 PF13465.6 KZN83799.1 - 8.6e-07 29.1 9.9 2.6e-06 27.6 0.9 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KZN83799.1 - 1.3e-05 25.1 1.3 0.021 14.8 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KZN83799.1 - 2.2e-05 24.7 0.8 2.2e-05 24.7 0.8 3.2 3 1 0 3 3 3 2 Zinc finger, C2H2 type SUIM_assoc PF16619.5 KZN83799.1 - 2.5e-05 24.3 0.9 0.00012 22.1 0.9 2.2 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 zf-C2H2_4 PF13894.6 KZN83799.1 - 0.00038 21.0 9.1 0.0035 18.1 0.5 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 KZN83799.1 - 0.0025 18.4 15.9 0.075 13.7 0.1 4.3 3 1 1 4 4 4 2 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 KZN83799.1 - 0.0056 16.9 1.0 0.29 11.5 0.3 2.8 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KZN83799.1 - 0.035 13.9 0.9 0.28 11.0 0.0 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type DivIC PF04977.15 KZN83799.1 - 4.2 7.2 5.0 4 7.3 1.3 2.2 2 0 0 2 2 2 0 Septum formation initiator SNF2_N PF00176.23 KZN83800.1 - 8.3e-56 189.2 0.0 1.3e-55 188.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 KZN83800.1 - 1.8e-24 85.4 1.7 1e-16 60.6 0.3 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.6 KZN83800.1 - 3.9e-21 75.3 1.4 8.2e-21 74.3 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 KZN83800.1 - 1.2e-18 67.5 0.0 3.2e-18 66.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Cdh1_DBD_1 PF18196.1 KZN83800.1 - 2.6e-06 27.8 1.2 2.7e-05 24.5 0.2 4.5 4 1 1 5 5 5 2 Chromodomain helicase DNA-binding domain 1 ResIII PF04851.15 KZN83800.1 - 3.2e-05 24.0 0.1 0.00072 19.6 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CHDCT2 PF08074.11 KZN83800.1 - 0.02 15.1 1.1 0.058 13.6 0.0 2.3 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain Rhodanese PF00581.20 KZN83800.1 - 0.061 13.9 0.1 6.6 7.3 0.1 2.9 2 0 0 2 2 2 0 Rhodanese-like domain SLIDE PF09111.10 KZN83800.1 - 0.061 13.3 0.1 0.45 10.6 0.0 2.6 3 0 0 3 3 3 0 SLIDE ABC_tran PF00005.27 KZN83801.1 - 1.3e-34 119.6 0.0 2.2e-16 60.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KZN83801.1 - 7.1e-11 42.0 1.6 0.0034 16.9 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KZN83801.1 - 5e-10 39.7 3.6 0.26 11.0 1.4 4.3 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KZN83801.1 - 9.1e-06 26.2 0.0 0.03 14.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KZN83801.1 - 1.6e-05 25.4 0.1 0.01 16.3 0.1 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KZN83801.1 - 3.5e-05 23.7 0.1 0.25 11.0 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain Rad17 PF03215.15 KZN83801.1 - 6.8e-05 22.9 0.1 0.022 14.7 0.0 2.8 2 1 1 3 3 3 1 Rad17 P-loop domain Fer4 PF00037.27 KZN83801.1 - 8.7e-05 22.2 2.5 8.7e-05 22.2 2.5 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_22 PF13401.6 KZN83801.1 - 0.00013 22.3 0.0 0.027 14.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KZN83801.1 - 0.00016 21.6 0.0 0.49 10.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Fer4_21 PF14697.6 KZN83801.1 - 0.00016 21.7 5.6 0.00029 20.9 5.6 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_33 PF13671.6 KZN83801.1 - 0.00055 20.1 0.0 0.08 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KZN83801.1 - 0.00059 19.5 0.2 0.72 9.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.22 KZN83801.1 - 0.00093 19.6 0.1 0.33 11.3 0.1 2.6 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 KZN83801.1 - 0.0027 17.4 2.1 0.14 11.8 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KZN83801.1 - 0.0033 18.0 0.2 0.45 11.0 0.1 2.5 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KZN83801.1 - 0.0033 17.4 0.3 0.032 14.2 0.1 2.2 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KZN83801.1 - 0.0035 17.3 1.7 0.2 11.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_7 PF12775.7 KZN83801.1 - 0.004 16.7 0.6 0.053 13.0 0.1 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region Fer4_6 PF12837.7 KZN83801.1 - 0.0093 16.0 2.2 0.0093 16.0 2.2 2.0 2 0 0 2 2 1 1 4Fe-4S binding domain Thymidylate_kin PF02223.17 KZN83801.1 - 0.0096 15.6 0.3 1.7 8.3 0.0 2.7 3 0 0 3 3 2 1 Thymidylate kinase SRP54 PF00448.22 KZN83801.1 - 0.011 15.4 3.6 0.14 11.8 0.2 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RLI PF04068.15 KZN83801.1 - 0.012 15.5 0.3 0.012 15.5 0.3 2.3 3 0 0 3 3 2 0 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_18 PF13238.6 KZN83801.1 - 0.026 15.1 3.8 3.1 8.4 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 KZN83801.1 - 0.026 14.3 0.7 1.3 8.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain Fer4_9 PF13187.6 KZN83801.1 - 0.026 14.7 5.4 0.059 13.6 5.4 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 KZN83801.1 - 0.027 14.6 1.6 0.027 14.6 1.6 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_13 PF13166.6 KZN83801.1 - 0.036 12.7 0.0 0.074 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KZN83801.1 - 0.038 14.0 0.2 1.7 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KZN83801.1 - 0.043 13.0 0.1 2.9 7.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Fer4_7 PF12838.7 KZN83801.1 - 0.043 14.4 6.2 0.14 12.7 6.4 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain AAA_28 PF13521.6 KZN83801.1 - 0.045 14.0 0.1 6.5 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KZN83801.1 - 0.055 12.6 0.1 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Fer4_16 PF13484.6 KZN83801.1 - 0.085 13.8 3.6 0.095 13.7 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain NTPase_1 PF03266.15 KZN83801.1 - 0.092 12.6 2.1 1.7 8.5 0.1 2.7 2 0 0 2 2 2 0 NTPase VirE PF05272.11 KZN83801.1 - 0.095 12.4 0.1 8.8 6.0 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E Fer4_17 PF13534.6 KZN83801.1 - 0.11 13.1 3.3 0.14 12.7 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain SbcCD_C PF13558.6 KZN83801.1 - 0.12 12.7 0.0 15 5.9 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.6 KZN83801.1 - 0.16 12.0 0.1 10 6.1 0.1 2.8 2 1 0 2 2 2 0 AAA domain MukB PF04310.12 KZN83801.1 - 0.47 10.2 2.0 30 4.3 0.1 2.9 3 0 0 3 3 3 0 MukB N-terminal PduV-EutP PF10662.9 KZN83801.1 - 0.57 9.9 3.1 0.42 10.3 0.1 2.3 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Fer4_8 PF13183.6 KZN83801.1 - 1.3 9.5 7.9 0.36 11.3 0.2 2.6 3 0 0 3 3 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 KZN83801.1 - 5.6 7.3 6.7 0.3 11.3 1.2 1.8 2 0 0 2 2 1 0 4Fe-4S binding domain MCRA PF06100.11 KZN83803.1 - 1.2e-145 486.2 0.0 1.4e-145 485.9 0.0 1.0 1 0 0 1 1 1 1 MCRA family FF PF01846.19 KZN83804.1 - 5.7e-55 183.3 19.3 4.6e-16 58.7 1.3 6.8 6 0 0 6 6 6 6 FF domain WW PF00397.26 KZN83804.1 - 1.9e-16 59.8 14.6 5.1e-08 32.9 0.8 2.7 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 KZN83804.1 - 0.0015 19.1 11.8 0.37 11.5 0.3 4.5 2 1 2 4 4 4 2 p190-A and -B Rho GAPs FF domain Glyco_hyd_101C PF17451.2 KZN83804.1 - 0.66 10.3 8.5 2.3 8.5 0.3 2.6 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Trs65 PF12735.7 KZN83805.1 - 1e-101 340.5 0.1 1.3e-101 340.1 0.1 1.1 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 Mpv17_PMP22 PF04117.12 KZN83806.1 - 2.8e-19 69.1 1.9 3.3e-19 68.8 0.1 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family PGK PF00162.19 KZN83807.1 - 3.7e-149 496.8 1.3 4.1e-149 496.6 1.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF3530 PF12048.8 KZN83807.1 - 0.011 15.2 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) PA PF02225.22 KZN83807.1 - 0.014 15.4 1.0 0.17 11.9 0.0 2.8 3 0 0 3 3 3 0 PA domain DSS1_SEM1 PF05160.13 KZN83808.1 - 1.4e-23 82.7 15.7 1.8e-23 82.4 15.7 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family DNA_pol_phi PF04931.13 KZN83808.1 - 0.71 7.9 9.2 0.78 7.8 9.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF3808 PF10300.9 KZN83809.1 - 9.3e-163 542.4 0.1 1.3e-162 541.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Pneumo_att_G PF05539.11 KZN83809.1 - 0.1 12.2 1.8 0.21 11.1 1.8 1.4 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G MFS_1 PF07690.16 KZN83810.1 - 8.7e-40 136.7 59.1 6.7e-39 133.8 34.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5455 PF17537.2 KZN83810.1 - 0.066 13.6 1.8 0.36 11.3 1.8 2.3 1 0 0 1 1 1 0 Family of unknown function (DUF5455) DUF2583 PF10762.9 KZN83810.1 - 0.25 11.8 8.4 2.1 8.8 0.4 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2583) AMP-binding PF00501.28 KZN83811.1 - 3.1e-279 925.4 0.0 2.9e-79 266.6 0.0 5.2 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.20 KZN83811.1 - 4.2e-253 840.0 0.0 1.8e-53 181.8 0.0 10.1 9 2 0 9 9 9 8 Condensation domain PP-binding PF00550.25 KZN83811.1 - 1.3e-46 156.8 7.8 6.7e-10 39.2 0.2 5.8 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KZN83811.1 - 2.4e-06 28.4 0.0 0.45 11.5 0.0 4.5 4 0 0 4 4 4 2 AMP-binding enzyme C-terminal domain Transferase PF02458.15 KZN83811.1 - 0.0029 16.3 0.0 1.5 7.3 0.0 3.0 3 0 0 3 3 3 2 Transferase family ABC_tran PF00005.27 KZN83812.1 - 9.2e-50 168.7 0.0 2.1e-26 93.1 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KZN83812.1 - 4.4e-29 102.0 28.8 5.2e-21 75.5 12.7 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KZN83812.1 - 1.4e-09 37.7 4.4 0.0033 16.9 1.1 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KZN83812.1 - 1.1e-06 29.2 0.1 0.0012 19.3 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KZN83812.1 - 2.1e-06 27.8 1.8 0.00091 19.1 0.1 3.4 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KZN83812.1 - 2.5e-06 27.5 0.2 0.00029 20.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KZN83812.1 - 3.5e-06 26.7 1.0 0.0016 18.2 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KZN83812.1 - 4.1e-05 23.3 0.2 0.0032 17.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KZN83812.1 - 4.7e-05 23.7 1.6 0.0076 16.5 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KZN83812.1 - 8.4e-05 22.4 0.3 0.26 11.0 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 KZN83812.1 - 8.5e-05 23.0 0.2 0.11 12.9 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KZN83812.1 - 0.00024 21.7 2.9 0.081 13.4 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KZN83812.1 - 0.00042 19.9 0.6 0.44 10.0 0.2 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region MMR_HSR1 PF01926.23 KZN83812.1 - 0.00051 20.1 0.3 0.25 11.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 KZN83812.1 - 0.0006 20.2 0.1 0.15 12.5 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_15 PF13175.6 KZN83812.1 - 0.00078 19.2 0.2 0.03 14.1 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 KZN83812.1 - 0.0015 17.6 0.1 0.091 11.8 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 KZN83812.1 - 0.002 17.9 1.9 6.6 6.4 0.0 4.0 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_33 PF13671.6 KZN83812.1 - 0.0026 17.9 0.0 0.097 12.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KZN83812.1 - 0.0076 16.2 0.0 0.62 10.0 0.0 2.7 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 KZN83812.1 - 0.012 14.8 0.3 4.4 6.4 0.0 2.6 2 1 0 2 2 2 0 NB-ARC domain Roc PF08477.13 KZN83812.1 - 0.013 15.8 0.7 12 6.1 0.0 3.4 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase ATP-synt_ab PF00006.25 KZN83812.1 - 0.02 14.6 0.2 2.8 7.6 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ATPase_2 PF01637.18 KZN83812.1 - 0.027 14.4 0.1 1.2 9.0 0.0 2.7 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 KZN83812.1 - 0.028 14.2 0.1 2 8.1 0.0 2.7 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase MobB PF03205.14 KZN83812.1 - 0.03 14.2 0.3 10 6.0 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.14 KZN83812.1 - 0.034 14.1 2.3 0.82 9.7 0.1 2.9 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KZN83812.1 - 0.037 13.7 1.0 4.7 6.9 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KZN83812.1 - 0.042 14.4 0.2 2.5 8.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 KZN83812.1 - 0.045 12.7 0.6 3.8 6.4 0.2 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 KZN83812.1 - 0.062 13.3 0.1 5.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KZN83812.1 - 0.064 12.8 1.5 3.3 7.3 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 KZN83812.1 - 0.065 13.2 0.2 0.18 11.7 0.2 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain NTPase_1 PF03266.15 KZN83812.1 - 0.068 13.1 2.1 1.4 8.8 0.3 2.4 2 0 0 2 2 2 0 NTPase DUF815 PF05673.13 KZN83812.1 - 0.094 11.9 0.3 1.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_11 PF13086.6 KZN83812.1 - 0.097 12.4 0.0 7.8 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.21 KZN83812.1 - 0.1 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase FtsK_SpoIIIE PF01580.18 KZN83812.1 - 0.12 11.7 0.3 5 6.4 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family Pox_A32 PF04665.12 KZN83812.1 - 0.15 11.5 0.8 7.6 5.9 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein Dynamin_N PF00350.23 KZN83812.1 - 0.16 12.0 0.2 2.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Dynamin family Zeta_toxin PF06414.12 KZN83812.1 - 0.17 11.1 0.1 22 4.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin PduV-EutP PF10662.9 KZN83812.1 - 0.23 11.2 1.0 2.7 7.7 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DEAD PF00270.29 KZN83812.1 - 0.52 10.1 1.5 5.1 6.8 1.5 2.5 2 1 0 2 2 2 0 DEAD/DEAH box helicase ABC_ATPase PF09818.9 KZN83812.1 - 0.53 9.0 3.7 0.2 10.4 0.1 2.1 3 0 0 3 3 3 0 Predicted ATPase of the ABC class ATP_bind_1 PF03029.17 KZN83812.1 - 0.54 10.0 1.5 7.5 6.3 0.3 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 KZN83812.1 - 0.88 9.8 3.1 0.35 11.1 0.2 1.8 2 0 0 2 2 1 0 AAA domain DUF87 PF01935.17 KZN83812.1 - 0.91 9.6 2.3 4.1 7.4 0.3 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Nup160 PF11715.8 KZN83813.1 - 1.9e-158 528.5 0.7 2.6e-158 528.0 0.7 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Rad51 PF08423.11 KZN83814.1 - 2.7e-128 426.6 0.0 3.2e-128 426.3 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KZN83814.1 - 5.1e-10 39.2 0.0 7.5e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KZN83814.1 - 1.6e-09 37.6 0.0 2.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 KZN83814.1 - 1.1e-06 29.1 0.2 3.8e-06 27.4 0.1 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 KZN83814.1 - 0.0002 20.8 1.3 0.0011 18.4 1.3 2.1 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 KZN83814.1 - 0.0079 15.6 0.1 0.042 13.2 0.0 1.9 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain ssDNA_TraI_N PF18272.1 KZN83814.1 - 0.094 12.7 0.3 0.58 10.2 0.1 2.3 3 0 0 3 3 3 0 single-stranded DNA binding TraI N-terminal subdomain AAA_22 PF13401.6 KZN83814.1 - 0.14 12.4 0.4 0.65 10.3 0.2 2.1 2 1 0 2 2 2 0 AAA domain PAXNEB PF05625.11 KZN83814.1 - 0.33 10.0 2.4 0.71 8.9 1.0 1.9 1 1 1 2 2 2 0 PAXNEB protein FAD_binding_4 PF01565.23 KZN83815.1 - 3.2e-15 56.1 0.1 4.8e-15 55.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 KZN83815.1 - 2.1e-05 24.5 2.2 4.6e-05 23.3 0.2 2.1 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase GMC_oxred_N PF00732.19 KZN83816.1 - 8.4e-82 274.9 0.0 1.1e-81 274.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 KZN83816.1 - 0.00014 21.2 0.1 0.0032 16.7 0.1 2.4 3 0 0 3 3 3 1 Thi4 family NAD_binding_8 PF13450.6 KZN83816.1 - 0.0023 18.1 0.0 0.0053 17.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KZN83816.1 - 0.003 17.2 2.3 0.0093 15.6 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KZN83816.1 - 0.0089 15.1 0.1 0.017 14.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KZN83816.1 - 0.083 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Fungal_trans PF04082.18 KZN83817.1 - 0.00014 21.0 0.0 0.00032 19.8 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Prefoldin PF02996.17 KZN83818.1 - 4.3e-25 87.9 0.3 5.7e-25 87.6 0.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KZN83818.1 - 0.003 17.5 1.6 0.082 12.9 0.7 2.1 2 0 0 2 2 2 1 Prefoldin subunit Med30 PF11315.8 KZN83818.1 - 0.084 13.1 0.2 1.2 9.3 0.2 2.1 2 0 0 2 2 2 0 Mediator complex subunit 30 Sec2p PF06428.11 KZN83818.1 - 0.1 12.6 1.9 1.2 9.2 0.3 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p CLZ PF16526.5 KZN83818.1 - 0.12 12.8 4.3 3.3 8.1 0.3 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DASH_Hsk3 PF08227.11 KZN83818.1 - 0.57 10.6 4.1 0.97 9.9 0.0 2.4 2 1 0 2 2 2 0 DASH complex subunit Hsk3 like AAA PF00004.29 KZN83820.1 - 2.5e-15 57.1 0.0 4.8e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 KZN83820.1 - 5.7e-12 45.6 0.8 3.1e-11 43.3 0.7 2.2 1 1 0 1 1 1 1 AAA lid domain AAA_22 PF13401.6 KZN83820.1 - 1.7e-09 38.0 0.0 4.7e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KZN83820.1 - 6.7e-09 36.4 1.3 5.3e-08 33.4 0.0 2.9 2 2 0 2 2 2 1 AAA ATPase domain BAH PF01426.18 KZN83820.1 - 1.3e-05 25.0 0.0 3.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 BAH domain AAA_28 PF13521.6 KZN83820.1 - 0.0012 19.1 0.0 0.0036 17.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KZN83820.1 - 0.0015 18.8 0.0 0.0035 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KZN83820.1 - 0.0059 16.4 0.2 0.022 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KZN83820.1 - 0.012 14.9 0.0 0.025 13.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_32 PF13654.6 KZN83820.1 - 0.014 14.2 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KZN83820.1 - 0.021 15.4 0.2 0.078 13.5 0.0 2.1 2 0 0 2 2 1 0 AAA domain PIF1 PF05970.14 KZN83820.1 - 0.037 13.2 0.4 0.086 12.0 0.0 1.7 2 0 0 2 2 2 0 PIF1-like helicase NACHT PF05729.12 KZN83820.1 - 0.042 13.8 0.0 0.1 12.5 0.0 1.7 1 1 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 KZN83820.1 - 0.043 13.0 0.1 0.72 9.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.6 KZN83820.1 - 0.063 13.0 0.6 0.14 11.9 0.1 1.8 2 0 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 KZN83820.1 - 0.075 12.9 0.0 1.2 9.0 0.0 2.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 KZN83820.1 - 0.081 13.1 0.0 1.1 9.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 KZN83820.1 - 0.083 12.1 0.0 0.27 10.4 0.0 1.8 2 0 0 2 2 2 0 KAP family P-loop domain Kinesin PF00225.23 KZN83820.1 - 0.085 11.8 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Kinesin motor domain ssDBP PF17878.1 KZN83820.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Single-stranded DNA-binding protein RNA_helicase PF00910.22 KZN83820.1 - 0.14 12.6 0.0 0.49 10.8 0.0 2.0 2 0 0 2 2 1 0 RNA helicase WD40 PF00400.32 KZN83821.1 - 1.1e-46 155.8 15.1 1.6e-09 38.2 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN83821.1 - 2.6e-07 30.8 0.4 2.4 8.5 0.1 5.2 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KZN83821.1 - 0.0055 16.1 0.0 0.015 14.7 0.0 1.7 2 0 0 2 2 2 1 WD40-like domain DUF5018 PF16410.5 KZN83821.1 - 0.015 14.1 0.0 0.027 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5018) Nup160 PF11715.8 KZN83821.1 - 0.035 12.8 2.4 10 4.7 0.0 4.3 1 1 3 5 5 5 0 Nucleoporin Nup120/160 Ank_5 PF13857.6 KZN83822.1 - 2.1e-32 110.7 0.1 4.3e-08 33.3 0.0 4.6 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KZN83822.1 - 2.5e-31 108.1 0.0 2.4e-11 44.1 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN83822.1 - 3.7e-30 103.9 0.6 4.8e-10 39.8 0.0 4.8 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN83822.1 - 2.3e-26 88.9 0.0 0.011 16.2 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 KZN83822.1 - 3.1e-21 74.8 0.2 0.011 16.2 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat LHH PF14411.6 KZN83822.1 - 0.2 11.9 0.0 1.3 9.3 0.0 2.2 3 0 0 3 3 3 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH FMO-like PF00743.19 KZN83823.1 - 1.1e-15 57.0 0.0 5e-15 54.9 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KZN83823.1 - 1.5e-09 37.5 0.9 9.3e-08 31.6 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KZN83823.1 - 5.6e-08 32.4 0.0 1.6e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KZN83823.1 - 8.2e-08 31.8 0.0 7.2e-07 28.7 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HATPase_c PF02518.26 KZN83823.1 - 0.092 13.3 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pyr_redox PF00070.27 KZN83823.1 - 0.16 12.6 0.0 0.56 10.8 0.0 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Retrotran_gag_2 PF14223.6 KZN83824.1 - 2.8e-05 23.8 0.2 4.8e-05 23.0 0.2 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 KZN83824.1 - 0.0055 16.5 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KZN83824.1 - 0.03 14.0 5.0 0.2 11.4 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4219) PTR2 PF00854.21 KZN83825.1 - 1.1e-59 202.3 7.0 1.8e-59 201.5 7.0 1.3 1 0 0 1 1 1 1 POT family ATPgrasp_N PF18130.1 KZN83826.1 - 1.3e-13 51.3 0.0 2.8e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 KZN83826.1 - 8.9e-12 44.9 0.0 9.6e-11 41.5 0.0 2.6 2 1 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KZN83826.1 - 8e-07 28.8 0.0 1.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 KZN83826.1 - 1.2e-05 24.9 0.0 0.00013 21.5 0.0 2.4 3 0 0 3 3 3 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 KZN83826.1 - 0.00094 19.3 0.0 0.02 14.9 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 KZN83826.1 - 0.0018 18.1 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GSH-S_ATP PF02955.16 KZN83826.1 - 0.099 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain RimK PF08443.11 KZN83826.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain FMO-like PF00743.19 KZN83827.1 - 3.3e-13 48.9 0.4 8.9e-13 47.5 0.0 1.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KZN83827.1 - 4.2e-11 42.9 0.0 9.8e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KZN83827.1 - 4.5e-08 32.7 0.3 5.2e-07 29.2 0.3 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KZN83827.1 - 2.3e-06 27.1 0.0 3.5e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KZN83827.1 - 2.8e-06 26.7 0.4 0.00014 21.1 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KZN83827.1 - 0.00071 19.3 0.8 0.18 11.3 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KZN83827.1 - 0.0014 18.7 0.1 0.12 12.4 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 KZN83827.1 - 0.004 16.4 0.1 0.015 14.6 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Glu_dehyd_C PF16912.5 KZN83827.1 - 0.077 12.5 0.2 5 6.5 0.0 2.7 3 0 0 3 3 3 0 Glucose dehydrogenase C-terminus Mqo PF06039.15 KZN83827.1 - 0.16 10.5 0.2 3.2 6.2 0.0 2.3 2 1 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_3 PF01494.19 KZN83827.1 - 0.21 10.8 0.6 0.6 9.3 0.3 1.8 2 0 0 2 2 2 0 FAD binding domain HNH_2 PF13391.6 KZN83828.1 - 9.6e-15 54.5 0.0 2.6e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease His_Phos_2 PF00328.22 KZN83829.1 - 9.7e-06 25.2 0.0 0.034 13.5 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) MFS_1 PF07690.16 KZN83830.1 - 1.2e-31 109.9 40.7 1.2e-31 109.9 40.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KZN83831.1 - 2.2e-60 204.5 3.5 2.7e-60 204.2 3.5 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN83831.1 - 4.4e-08 33.1 10.4 7.5e-08 32.4 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain V-ATPase_H_N PF03224.14 KZN83832.1 - 1.2e-81 274.4 0.0 1.8e-81 273.9 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KZN83832.1 - 9.6e-37 125.7 0.0 3.5e-36 123.9 0.0 2.0 2 0 0 2 2 2 1 V-ATPase subunit H Arm PF00514.23 KZN83832.1 - 0.011 15.7 0.0 0.064 13.3 0.0 2.4 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat TMF_TATA_bd PF12325.8 KZN83833.1 - 1.6e-38 131.4 11.9 1.6e-38 131.4 11.9 6.9 2 1 4 7 7 7 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KZN83833.1 - 1e-20 73.5 17.0 1e-20 73.5 17.0 9.1 5 4 3 9 9 9 1 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 KZN83833.1 - 1.4e-05 25.5 3.2 1.4e-05 25.5 3.2 5.6 3 1 2 5 5 5 3 Autophagy protein 16 (ATG16) NPV_P10 PF05531.12 KZN83833.1 - 0.67 10.5 31.3 0.16 12.5 1.4 6.4 7 1 1 8 8 8 0 Nucleopolyhedrovirus P10 protein DASH_Dam1 PF08653.10 KZN83833.1 - 3.8 7.4 7.1 12 5.8 0.2 4.3 2 2 2 4 4 4 0 DASH complex subunit Dam1 Filament PF00038.21 KZN83836.1 - 0.00046 19.9 5.6 0.00046 19.9 5.6 5.5 4 1 1 6 6 6 3 Intermediate filament protein MatP_C PF17414.2 KZN83836.1 - 0.45 10.8 5.0 0.8 9.9 2.8 2.7 2 1 1 3 3 3 0 MatP C-terminal ribbon-helix-helix domain Apq12 PF12716.7 KZN83837.1 - 3.2e-18 65.4 13.4 3.2e-18 65.4 13.4 1.5 2 0 0 2 2 2 1 Nuclear pore assembly and biogenesis ATP_bind_1 PF03029.17 KZN83838.1 - 1e-76 257.9 0.2 1.2e-76 257.7 0.2 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 KZN83838.1 - 0.00058 19.9 0.0 0.0015 18.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 KZN83838.1 - 0.00099 18.2 0.1 0.0028 16.8 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_33 PF13671.6 KZN83838.1 - 0.0021 18.2 0.0 0.0041 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KZN83838.1 - 0.0024 18.3 0.0 0.0068 16.8 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 KZN83838.1 - 0.0056 17.0 0.1 0.11 12.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KZN83838.1 - 0.0058 17.1 0.0 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KZN83838.1 - 0.0097 15.1 0.4 0.073 12.2 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain CLP1_P PF16575.5 KZN83838.1 - 0.016 15.0 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_22 PF13401.6 KZN83838.1 - 0.019 15.3 0.0 0.046 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KZN83838.1 - 0.021 14.6 0.1 0.076 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KZN83838.1 - 0.021 15.2 0.0 0.054 13.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KZN83838.1 - 0.022 14.3 0.0 0.047 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KZN83838.1 - 0.024 14.5 0.2 0.56 10.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 KZN83838.1 - 0.027 14.5 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE KAP_NTPase PF07693.14 KZN83838.1 - 0.038 13.2 0.0 0.085 12.1 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain GTP_EFTU PF00009.27 KZN83838.1 - 0.038 13.5 0.1 5.1 6.6 0.1 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 KZN83838.1 - 0.043 14.3 0.0 0.091 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.15 KZN83838.1 - 0.049 12.8 0.2 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 Anion-transporting ATPase AAA_24 PF13479.6 KZN83838.1 - 0.06 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KZN83838.1 - 0.061 12.9 0.2 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Sigma54_activat PF00158.26 KZN83838.1 - 0.062 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_31 PF13614.6 KZN83838.1 - 0.065 13.1 0.0 5.4 6.9 0.0 2.3 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KZN83838.1 - 0.066 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 KZN83838.1 - 0.078 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Septin PF00735.18 KZN83838.1 - 0.087 12.1 0.0 0.18 11.1 0.0 1.5 2 0 0 2 2 1 0 Septin Zeta_toxin PF06414.12 KZN83838.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ATPase_2 PF01637.18 KZN83838.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Thymidylate_kin PF02223.17 KZN83838.1 - 0.11 12.1 0.0 0.62 9.7 0.0 2.1 2 1 0 2 2 2 0 Thymidylate kinase ABC_tran PF00005.27 KZN83838.1 - 0.12 12.9 0.0 0.34 11.4 0.0 1.7 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 KZN83838.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 KZN83838.1 - 0.17 11.7 0.0 0.48 10.3 0.0 1.7 2 0 0 2 2 1 0 NTPase MMR_HSR1 PF01926.23 KZN83838.1 - 0.19 11.8 0.0 0.43 10.7 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase S-AdoMet_synt_C PF02773.16 KZN83839.1 - 1.1e-67 226.3 0.6 4e-66 221.2 0.1 2.2 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_N PF00438.20 KZN83839.1 - 7.4e-44 148.5 0.5 1.7e-43 147.3 0.1 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.16 KZN83839.1 - 1.2e-43 148.2 0.0 2.4e-43 147.2 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain Lactamase_B_3 PF13483.6 KZN83839.1 - 0.089 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain SLD3 PF08639.10 KZN83840.1 - 8.2e-166 552.9 10.5 8.2e-166 552.9 10.5 1.6 2 0 0 2 2 2 1 DNA replication regulator SLD3 DASH_Spc19 PF08287.11 KZN83840.1 - 1.4 8.8 9.0 1.8 8.4 0.5 2.6 2 0 0 2 2 2 0 Spc19 SfLAP PF11139.8 KZN83841.1 - 0.0007 19.1 0.9 0.0027 17.2 0.8 1.9 2 0 0 2 2 2 1 Sap, sulfolipid-1-addressing protein DUF420 PF04238.12 KZN83841.1 - 0.012 15.9 4.3 0.02 15.2 2.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF420) DUF3429 PF11911.8 KZN83841.1 - 0.031 14.6 1.3 0.1 12.9 1.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3429) MIG-14_Wnt-bd PF06664.12 KZN83841.1 - 0.2 10.8 19.8 0.052 12.8 4.0 3.0 1 1 0 2 2 2 0 Wnt-binding factor required for Wnt secretion DUF3671 PF12420.8 KZN83841.1 - 0.59 10.2 9.4 1.9 8.6 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function YoqO PF14037.6 KZN83841.1 - 1 9.9 16.3 1 9.9 9.1 2.8 2 1 1 3 3 3 0 YoqO-like protein SpoIIIAC PF06686.11 KZN83841.1 - 3.3 8.0 9.4 0.56 10.4 0.4 3.0 3 0 0 3 3 3 0 Stage III sporulation protein AC/AD protein family SERTA PF06031.13 KZN83843.1 - 0.16 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 SERTA motif GFA PF04828.14 KZN83845.1 - 7.2e-21 74.3 1.1 1.3e-20 73.5 1.1 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 KZN83845.1 - 0.25 11.5 3.8 3.2 8.0 0.1 2.5 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like CRC_subunit PF08624.10 KZN83847.1 - 5.1e-49 166.2 0.0 7.7e-49 165.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit F-box-like PF12937.7 KZN83848.1 - 0.0025 17.7 1.5 0.017 15.0 0.0 3.0 4 0 0 4 4 4 1 F-box-like His_Phos_1 PF00300.22 KZN83849.1 - 4.1e-07 29.9 0.1 1.4e-06 28.1 0.1 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Homeodomain PF00046.29 KZN83850.1 - 8.5e-17 60.7 3.3 1.5e-16 60.0 2.4 1.9 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KZN83850.1 - 3.3e-06 26.9 0.5 9.6e-06 25.4 0.5 1.8 1 0 0 1 1 1 1 Homeobox KN domain DUF4638 PF15472.6 KZN83850.1 - 0.13 11.9 7.4 0.23 11.1 7.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) HAD_2 PF13419.6 KZN83851.1 - 2.1e-19 70.3 0.0 2.9e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KZN83851.1 - 2.1e-08 34.7 0.0 3.6e-06 27.4 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KZN83851.1 - 3.9e-06 27.4 0.0 6.6e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KZN83851.1 - 0.00014 21.9 0.0 0.00031 20.7 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like GN3L_Grn1 PF08701.11 KZN83852.1 - 5e-22 77.8 18.1 5e-22 77.8 18.1 2.0 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 KZN83852.1 - 2.7e-18 66.1 0.1 7.3e-14 51.8 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KZN83852.1 - 3.2e-07 30.4 0.0 5.1e-06 26.5 0.0 2.3 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 KZN83852.1 - 1.1e-05 25.1 0.4 0.16 11.4 0.6 3.2 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KZN83852.1 - 1.8e-05 24.4 0.0 0.00021 20.9 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KZN83852.1 - 0.00028 21.0 8.9 0.44 10.6 0.1 4.5 3 2 1 4 4 4 2 Dynamin family MeaB PF03308.16 KZN83852.1 - 0.0054 15.8 0.0 0.0054 15.8 0.0 2.0 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 KZN83852.1 - 0.051 13.2 0.0 1.4 8.4 0.0 2.7 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NOG1 PF06858.14 KZN83852.1 - 0.07 12.9 0.1 7.8 6.4 0.1 3.3 2 1 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) RNA_pol_3_Rpc31 PF11705.8 KZN83852.1 - 0.086 13.1 18.0 0.26 11.5 18.0 1.8 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Roc PF08477.13 KZN83852.1 - 0.09 13.0 0.0 22 5.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KZN83852.1 - 0.1 12.1 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_18 PF13238.6 KZN83852.1 - 0.17 12.4 2.8 0.19 12.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain HEXIM PF15313.6 KZN83852.1 - 0.38 11.0 9.4 1.1 9.4 9.4 1.8 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein RRN3 PF05327.11 KZN83852.1 - 0.48 8.9 4.9 0.62 8.5 4.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 AAA_16 PF13191.6 KZN83852.1 - 0.74 10.2 0.0 0.74 10.2 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain NOA36 PF06524.12 KZN83852.1 - 3.5 6.9 18.7 6.8 5.9 18.7 1.5 1 0 0 1 1 1 0 NOA36 protein CBFD_NFYB_HMF PF00808.23 KZN83853.1 - 1.9e-05 24.8 0.0 4.3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KZN83853.1 - 0.024 15.0 0.2 0.083 13.2 0.0 2.0 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 TFIIA PF03153.13 KZN83853.1 - 0.19 11.7 14.3 0.26 11.3 14.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Na_trans_assoc PF06512.13 KZN83853.1 - 0.45 10.8 12.3 0.65 10.2 12.3 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated CENP-X PF09415.10 KZN83853.1 - 1.3 9.4 0.0 1.3 9.4 0.0 2.6 2 0 0 2 2 2 0 CENP-S associating Centromere protein X BUD22 PF09073.10 KZN83853.1 - 2.1 7.6 18.5 3 7.1 18.5 1.3 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 KZN83853.1 - 5.1 5.8 5.4 5.3 5.7 5.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SIR2 PF02146.17 KZN83854.1 - 3e-29 102.2 0.0 9.8e-29 100.5 0.0 1.8 1 1 0 1 1 1 1 Sir2 family Med16 PF11635.8 KZN83855.1 - 1.4e-200 668.0 0.0 2.1e-200 667.5 0.0 1.2 1 0 0 1 1 1 1 Mediator complex subunit 16 ANAPC4_WD40 PF12894.7 KZN83855.1 - 0.00049 20.3 0.1 0.71 10.2 0.0 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L29 PF00831.23 KZN83856.1 - 8.6e-18 64.1 1.1 8.6e-18 64.1 1.1 2.1 2 1 1 3 3 3 1 Ribosomal L29 protein CorA PF01544.18 KZN83856.1 - 0.1 11.9 3.2 0.12 11.6 3.2 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein V-SNARE_C PF12352.8 KZN83857.1 - 6.8e-12 45.5 0.0 6.8e-12 45.5 0.0 2.6 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus GOLGA2L5 PF15070.6 KZN83857.1 - 0.015 14.0 8.6 0.013 14.2 7.6 1.3 1 1 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Sec20 PF03908.13 KZN83857.1 - 0.023 14.6 1.3 1.8 8.6 0.0 3.1 3 1 0 3 3 3 0 Sec20 STAT_alpha PF01017.20 KZN83857.1 - 0.046 13.6 2.6 0.16 11.9 2.2 1.9 1 1 1 2 2 2 0 STAT protein, all-alpha domain DUF2890 PF11081.8 KZN83857.1 - 0.085 13.0 0.5 0.24 11.5 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2890) TIP120 PF08623.10 KZN83857.1 - 0.14 11.9 0.6 0.22 11.3 0.6 1.3 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) Syntaxin-6_N PF09177.11 KZN83857.1 - 0.21 12.2 6.4 0.14 12.7 4.0 2.0 2 2 0 2 2 2 0 Syntaxin 6, N-terminal CENP-H PF05837.12 KZN83857.1 - 1.1 9.7 9.0 0.69 10.3 6.2 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) ATP-synt_10 PF05176.14 KZN83858.1 - 2.2e-83 279.5 0.0 2.7e-83 279.1 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein NolB PF17398.2 KZN83858.1 - 0.11 12.9 0.0 12 6.3 0.0 2.6 3 0 0 3 3 3 0 Nodulation protein NolB Phosphodiest PF01663.22 KZN83860.1 - 2.1e-08 34.2 0.1 9.2e-08 32.1 0.0 1.7 1 1 1 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KZN83860.1 - 0.0026 17.2 0.0 0.0043 16.4 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KZN83860.1 - 0.011 15.1 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Sulfatase adh_short PF00106.25 KZN83861.1 - 4.9e-18 65.3 0.0 6.3e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN83861.1 - 5.5e-11 42.5 0.0 7.5e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN83861.1 - 0.0007 19.5 0.0 0.0009 19.2 0.0 1.1 1 0 0 1 1 1 1 KR domain MVL PF12151.8 KZN83861.1 - 0.14 12.0 0.2 0.63 9.9 0.1 2.0 2 0 0 2 2 2 0 Mannan-binding protein MFS_1 PF07690.16 KZN83862.1 - 3.4e-42 144.6 64.9 1.1e-41 143.0 61.7 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KZN83862.1 - 4.8e-14 51.7 30.0 3e-13 49.1 28.5 2.2 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KZN83862.1 - 4.2e-12 45.7 11.3 4.2e-12 45.7 11.3 3.5 4 0 0 4 4 4 1 Sugar (and other) transporter TMEM100 PF16311.5 KZN83862.1 - 1.8 8.2 5.0 3.5 7.2 0.0 2.8 3 0 0 3 3 3 0 Transmembrane protein 100 AXE1 PF05448.12 KZN83863.1 - 2.4e-07 29.7 0.1 3.6e-07 29.2 0.1 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 KZN83863.1 - 2e-06 28.6 0.3 2.3e-06 28.4 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KZN83863.1 - 1.2e-05 24.7 0.1 2.9e-05 23.5 0.1 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KZN83863.1 - 1.6e-05 24.5 0.2 0.0031 17.0 0.1 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family BAAT_C PF08840.11 KZN83863.1 - 1.9e-05 24.7 0.0 3.9e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 KZN83863.1 - 0.00039 20.1 0.0 0.0012 18.5 0.0 1.8 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 KZN83863.1 - 0.0015 18.1 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Esterase PF00756.20 KZN83863.1 - 0.17 11.5 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF3990 PF13151.6 KZN83864.1 - 0.0044 16.7 0.0 0.0081 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3990) KR PF08659.10 KZN83865.1 - 9.4e-53 178.8 0.0 1.8e-52 177.8 0.0 1.5 1 0 0 1 1 1 1 KR domain ADH_zinc_N_2 PF13602.6 KZN83865.1 - 2.1e-18 67.7 0.0 9.7e-18 65.5 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KZN83865.1 - 4.3e-14 52.6 0.0 1.2e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KZN83865.1 - 2.2e-07 30.5 0.0 1.5e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.6 KZN83865.1 - 0.00011 21.6 0.0 0.00015 21.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_N PF08240.12 KZN83865.1 - 0.0019 18.1 0.0 0.0038 17.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.21 KZN83865.1 - 0.1 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 KZN83865.1 - 0.14 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase YjeF_N PF03853.15 KZN83865.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus Fungal_trans_2 PF11951.8 KZN83866.1 - 0.0026 16.6 0.1 0.0044 15.9 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain RTA1 PF04479.13 KZN83867.1 - 5.7e-64 215.5 3.2 7.5e-64 215.1 3.2 1.1 1 0 0 1 1 1 1 RTA1 like protein TraQ PF09679.10 KZN83867.1 - 0.056 13.4 0.1 0.18 11.8 0.1 1.8 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) DNA_pol_B_palm PF14792.6 KZN83868.1 - 4.1e-35 120.4 0.0 8.3e-35 119.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 KZN83868.1 - 4.4e-25 87.6 0.0 9e-25 86.6 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.6 KZN83868.1 - 1.6e-19 70.0 0.7 3.2e-19 69.1 0.7 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 KZN83868.1 - 1e-15 57.3 0.0 3.4e-15 55.6 0.0 2.0 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda BRCT PF00533.26 KZN83868.1 - 0.00067 20.0 0.0 0.005 17.2 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain NTP_transf_2 PF01909.23 KZN83868.1 - 0.015 15.5 0.0 0.04 14.2 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain PTCB-BRCT PF12738.7 KZN83868.1 - 0.072 13.1 0.0 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 twin BRCT domain Zn_clus PF00172.18 KZN83869.1 - 0.004 17.3 4.7 0.01 16.0 4.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TF_Zn_Ribbon PF08271.12 KZN83869.1 - 0.03 13.8 0.8 0.3 10.6 0.0 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zf-BED PF02892.15 KZN83869.1 - 0.037 14.0 0.3 0.091 12.8 0.3 1.6 1 0 0 1 1 1 0 BED zinc finger CPL PF08144.11 KZN83871.1 - 2.1e-27 96.2 0.0 2.1e-27 96.2 0.0 3.9 4 0 0 4 4 4 2 CPL (NUC119) domain AA_permease PF00324.21 KZN83874.1 - 2e-136 455.4 43.8 2.4e-136 455.1 43.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KZN83874.1 - 4.3e-36 124.7 50.2 5.2e-36 124.4 50.2 1.0 1 0 0 1 1 1 1 Amino acid permease COX7C PF02935.16 KZN83874.1 - 0.29 11.4 4.8 3.3 8.0 0.6 3.6 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc MFS_1 PF07690.16 KZN83875.1 - 3.1e-16 59.3 59.0 3.5e-12 45.9 28.7 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KZN83875.1 - 3.9e-12 45.4 28.3 5.9e-12 44.8 28.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.12 KZN83875.1 - 0.0029 17.7 1.5 0.017 15.3 1.5 2.4 1 0 0 1 1 1 1 Poxvirus virion envelope protein A14 Arylsulfotran_2 PF14269.6 KZN83876.1 - 9.1e-119 396.3 4.0 1.1e-118 396.0 4.0 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KZN83876.1 - 2e-12 46.7 1.0 7.5e-11 41.6 1.0 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Acetyltransf_1 PF00583.25 KZN83877.1 - 3e-12 46.8 0.0 6.8e-12 45.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KZN83877.1 - 2e-11 44.2 0.0 3.6e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KZN83877.1 - 1.6e-10 41.0 0.0 6.2e-10 39.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KZN83877.1 - 0.00029 20.9 0.1 0.0029 17.7 0.0 2.3 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KZN83877.1 - 0.0047 17.0 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KZN83877.1 - 0.048 13.6 0.0 0.24 11.4 0.0 2.1 1 1 0 1 1 1 0 FR47-like protein Pyr_redox_2 PF07992.14 KZN83878.1 - 9.6e-24 84.1 0.1 8.8e-23 81.0 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KZN83878.1 - 7.9e-13 48.8 3.2 1.5e-11 44.7 0.3 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KZN83878.1 - 2.5e-06 27.0 0.0 6.2e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KZN83878.1 - 0.00028 20.1 0.1 0.00047 19.4 0.1 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 KZN83878.1 - 0.00032 19.7 1.2 1.3 7.7 0.9 3.5 4 0 0 4 4 4 2 Tryptophan halogenase Lycopene_cycl PF05834.12 KZN83878.1 - 0.0024 17.0 1.4 0.027 13.5 0.3 2.1 1 1 1 2 2 2 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KZN83878.1 - 0.0062 15.9 0.2 0.047 13.0 0.3 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 KZN83878.1 - 0.01 15.2 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase DAO PF01266.24 KZN83878.1 - 0.012 15.2 1.2 0.82 9.2 0.5 3.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KZN83878.1 - 0.016 14.0 1.1 0.21 10.2 0.6 2.4 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_9 PF13454.6 KZN83878.1 - 0.041 13.9 3.1 0.61 10.1 0.0 3.4 3 1 1 4 4 4 0 FAD-NAD(P)-binding MCRA PF06100.11 KZN83878.1 - 0.11 11.3 0.0 0.31 9.8 0.0 1.6 2 0 0 2 2 2 0 MCRA family FAD_binding_3 PF01494.19 KZN83878.1 - 0.21 10.8 1.2 3.2 6.9 0.1 2.3 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 KZN83878.1 - 0.36 10.1 5.4 8.3 5.6 0.0 3.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase ABC_membrane PF00664.23 KZN83879.1 - 6.7e-86 288.3 31.1 1.5e-48 165.8 10.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KZN83879.1 - 4.8e-66 221.5 0.0 2.1e-32 112.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KZN83879.1 - 6.8e-16 58.4 0.9 2.6e-05 23.8 0.0 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KZN83879.1 - 1.4e-07 31.1 0.9 0.0024 17.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KZN83879.1 - 1.7e-06 28.5 2.2 0.034 14.5 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KZN83879.1 - 3.2e-06 27.5 1.1 0.11 12.7 0.1 4.1 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KZN83879.1 - 5.1e-05 23.2 0.0 0.073 13.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 KZN83879.1 - 8.5e-05 21.5 0.1 0.014 14.2 0.0 2.6 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_30 PF13604.6 KZN83879.1 - 9.2e-05 22.2 4.9 0.034 13.9 0.0 3.5 3 1 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 KZN83879.1 - 0.00022 20.6 0.1 0.52 9.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin APS_kinase PF01583.20 KZN83879.1 - 0.00033 20.6 0.2 0.2 11.5 0.1 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_33 PF13671.6 KZN83879.1 - 0.0011 19.1 0.0 2.1 8.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 KZN83879.1 - 0.0013 19.2 0.9 0.77 10.3 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_23 PF13476.6 KZN83879.1 - 0.0023 18.5 0.2 0.42 11.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KZN83879.1 - 0.003 17.1 0.0 2.5 7.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KZN83879.1 - 0.005 16.7 0.3 0.32 10.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 KZN83879.1 - 0.0066 16.6 0.1 2.2 8.3 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_24 PF13479.6 KZN83879.1 - 0.0071 16.1 0.0 2.8 7.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KZN83879.1 - 0.009 16.2 2.0 3.6 7.9 0.1 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 KZN83879.1 - 0.014 15.4 0.0 3.4 7.7 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KZN83879.1 - 0.023 15.1 0.7 47 4.4 0.0 4.0 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) DUF3987 PF13148.6 KZN83879.1 - 0.025 13.6 0.0 1.1 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) MMR_HSR1 PF01926.23 KZN83879.1 - 0.032 14.3 0.1 5.2 7.2 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase NB-ARC PF00931.22 KZN83879.1 - 0.15 11.2 0.3 20 4.3 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain AAA_17 PF13207.6 KZN83879.1 - 0.16 12.4 0.5 36 4.8 0.0 3.0 3 0 0 3 3 2 0 AAA domain Acetyltransf_8 PF13523.6 KZN83880.1 - 4.4e-44 149.7 0.9 6.2e-44 149.2 0.9 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AMP-binding PF00501.28 KZN83881.1 - 2.8e-78 263.4 0.0 1.4e-77 261.1 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.20 KZN83881.1 - 4.8e-67 226.6 0.0 1.8e-38 132.4 0.0 2.2 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 KZN83881.1 - 1.4e-24 86.2 2.2 9e-13 48.4 0.2 3.2 3 0 0 3 3 3 2 Phosphopantetheine attachment site OST3_OST6 PF04756.13 KZN83884.1 - 0.17 11.2 2.0 1 8.6 2.7 1.8 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family GPI2 PF06432.11 KZN83884.1 - 1.9 7.8 10.2 0.36 10.2 5.6 1.9 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase ketoacyl-synt PF00109.26 KZN83885.1 - 2.2e-75 253.5 0.5 5.8e-75 252.1 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KZN83885.1 - 3.2e-58 196.6 0.0 6.9e-58 195.5 0.0 1.6 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KZN83885.1 - 2.7e-48 164.8 0.0 4.3e-48 164.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KZN83885.1 - 2.8e-48 165.0 0.0 5.1e-48 164.2 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KZN83885.1 - 6.7e-37 126.1 0.0 1.8e-36 124.7 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KZN83885.1 - 1.2e-20 74.0 0.0 3.3e-20 72.6 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KZN83885.1 - 1.9e-11 43.8 0.0 5.1e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.25 KZN83885.1 - 2.3e-06 27.9 0.7 7.2e-06 26.3 0.1 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 KZN83885.1 - 3.6e-05 23.4 0.0 9.9e-05 22.0 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 KZN83885.1 - 0.00014 21.3 0.1 0.00029 20.3 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain SAT PF16073.5 KZN83885.1 - 0.0045 16.7 0.9 0.11 12.2 0.0 3.1 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ACP_syn_III PF08545.10 KZN83885.1 - 0.0057 16.5 0.4 0.031 14.1 0.1 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_N PF08240.12 KZN83885.1 - 0.042 13.7 0.0 0.083 12.8 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN83886.1 - 1e-09 38.5 0.1 2.4e-09 37.3 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KZN83886.1 - 0.00033 20.5 0.2 0.001 18.9 0.1 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KZN83886.1 - 0.051 14.6 0.1 0.69 11.0 0.1 2.5 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Cupin_2 PF07883.11 KZN83887.1 - 1.9e-20 72.4 0.3 3.2e-10 39.6 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KZN83887.1 - 2.2e-18 65.7 1.2 4.7e-15 55.0 0.3 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KZN83887.1 - 4e-05 23.5 0.1 0.035 14.0 0.0 2.2 2 0 0 2 2 2 2 AraC-like ligand binding domain CENP-C_C PF11699.8 KZN83887.1 - 0.00011 22.3 0.0 0.00022 21.4 0.0 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like KR PF08659.10 KZN83888.1 - 1e-20 74.4 0.0 2.3e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 KZN83888.1 - 4.2e-08 33.2 0.0 8.3e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KZN83888.1 - 1.4e-05 24.7 0.0 0.0001 21.9 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN83888.1 - 0.0084 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ThiF PF00899.21 KZN83888.1 - 0.024 14.0 0.0 0.2 11.0 0.0 2.3 3 0 0 3 3 3 0 ThiF family PP-binding PF00550.25 KZN83888.1 - 0.031 14.6 0.0 0.072 13.5 0.0 1.5 1 0 0 1 1 1 0 Phosphopantetheine attachment site MCRA PF06100.11 KZN83889.1 - 6.8e-168 559.5 0.0 7.8e-168 559.3 0.0 1.0 1 0 0 1 1 1 1 MCRA family Ank_2 PF12796.7 KZN83893.1 - 2.8e-57 191.2 0.2 5e-15 55.9 0.0 6.0 1 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KZN83893.1 - 4.4e-45 151.1 9.2 1.6e-10 41.0 0.0 7.9 5 1 3 8 8 8 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 KZN83893.1 - 1.7e-41 140.0 9.9 2.2e-10 40.9 0.0 7.4 6 1 2 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 KZN83893.1 - 3.2e-38 128.5 7.6 2e-05 24.8 0.0 11.4 11 1 0 11 11 11 7 Ankyrin repeat Ank_3 PF13606.6 KZN83893.1 - 1.1e-35 117.5 9.1 0.00011 22.3 0.0 11.1 11 0 0 11 11 11 7 Ankyrin repeat NACHT PF05729.12 KZN83893.1 - 4.3e-06 26.7 0.0 1.9e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 NACHT domain SesA PF17107.5 KZN83893.1 - 0.00038 20.6 0.2 0.001 19.2 0.2 1.7 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_22 PF13401.6 KZN83893.1 - 0.02 15.2 0.0 0.048 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Lyase_aromatic PF00221.19 KZN83894.1 - 9.3e-146 486.1 6.9 1.2e-145 485.7 6.9 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Pkinase PF00069.25 KZN83895.1 - 2.3e-28 99.3 0.0 6.1e-17 61.8 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KZN83895.1 - 7.9e-12 45.0 0.0 3.9e-06 26.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KZN83895.1 - 0.067 13.1 0.1 0.48 10.3 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 KZN83895.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KZN83895.1 - 0.11 11.2 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Sugar_tr PF00083.24 KZN83896.1 - 9e-99 331.3 36.2 1e-98 331.1 36.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN83896.1 - 4.2e-29 101.6 37.3 4.2e-29 101.6 37.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily AA_permease_2 PF13520.6 KZN83898.1 - 3.1e-44 151.5 45.8 3.7e-44 151.2 45.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN83898.1 - 2.8e-22 79.0 41.3 5.1e-22 78.1 41.3 1.3 1 1 0 1 1 1 1 Amino acid permease DUF594 PF04578.13 KZN83899.1 - 0.016 14.7 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF594 Acetyltransf_1 PF00583.25 KZN83900.1 - 1.1e-07 32.1 0.0 1.6e-07 31.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KZN83900.1 - 1.3e-07 31.9 0.0 2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KZN83900.1 - 3.5e-07 30.2 0.0 5.3e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RTA1 PF04479.13 KZN83902.1 - 4.9e-70 235.3 7.5 6.7e-70 234.9 7.5 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF4231 PF14015.6 KZN83902.1 - 0.14 12.7 1.1 6.4 7.3 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) Mannosidase_ig PF17786.1 KZN83903.1 - 5e-19 68.7 0.3 3.1e-18 66.2 0.1 2.4 3 0 0 3 3 3 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KZN83903.1 - 3.7e-14 53.3 0.0 8.1e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 KZN83903.1 - 0.058 13.3 0.0 0.2 11.6 0.0 1.9 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Sugar_tr PF00083.24 KZN83904.1 - 5.6e-66 223.3 24.9 6.4e-66 223.1 24.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN83904.1 - 5.7e-31 107.7 43.7 1.3e-25 90.1 24.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KZN83904.1 - 9.6e-09 34.2 2.8 2e-08 33.2 2.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Yae1_N PF09811.9 KZN83904.1 - 0.19 11.4 0.2 0.46 10.2 0.2 1.6 1 0 0 1 1 1 0 Essential protein Yae1, N terminal HXXEE PF13787.6 KZN83904.1 - 0.27 12.0 6.2 0.48 11.3 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif Fungal_trans PF04082.18 KZN83905.1 - 3.6e-16 59.0 0.0 5.8e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN83905.1 - 1.4e-06 28.3 11.9 2.6e-06 27.4 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aconitase PF00330.20 KZN83906.1 - 1.3e-111 373.9 0.6 9.5e-111 371.0 0.6 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KZN83906.1 - 4.5e-23 82.0 0.0 7.6e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain AA_permease PF00324.21 KZN83907.1 - 7.5e-93 311.7 41.8 8.6e-93 311.5 41.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KZN83907.1 - 2.9e-25 89.0 44.1 3.6e-25 88.7 44.1 1.0 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_2_C PF02836.17 KZN83908.1 - 2.2e-91 306.1 0.0 3e-91 305.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KZN83908.1 - 2.7e-23 82.7 0.0 7.2e-23 81.3 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KZN83908.1 - 5.7e-12 46.3 0.4 1.3e-11 45.1 0.4 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Big_5 PF13205.6 KZN83908.1 - 0.032 14.9 0.4 0.087 13.5 0.4 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain FMO-like PF00743.19 KZN83909.1 - 2.9e-17 62.3 0.5 8.8e-16 57.4 0.2 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KZN83909.1 - 1e-07 32.1 0.0 4.2e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KZN83909.1 - 0.00011 21.6 0.0 0.00085 18.7 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KZN83909.1 - 0.002 17.3 0.0 0.042 13.0 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) S_locus_glycop PF00954.20 KZN83909.1 - 0.055 14.0 2.9 0.54 10.8 0.2 2.4 2 0 0 2 2 2 0 S-locus glycoprotein domain NAD_binding_9 PF13454.6 KZN83909.1 - 0.088 12.8 0.2 1.4 8.9 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding Abhydrolase_3 PF07859.13 KZN83910.1 - 8.2e-50 169.6 0.0 1.2e-49 169.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KZN83910.1 - 2.4e-13 49.8 1.2 8e-13 48.1 0.3 2.1 2 1 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KZN83910.1 - 4.4e-06 27.4 0.0 5.9e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FMO-like PF00743.19 KZN83911.1 - 5.5e-17 61.4 0.0 8.1e-16 57.5 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KZN83911.1 - 3.2e-09 36.9 0.0 8.9e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KZN83911.1 - 7.4e-08 32.0 0.0 8.2e-05 22.0 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KZN83911.1 - 4.7e-06 26.1 0.0 0.00027 20.3 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KZN83911.1 - 6.3e-05 22.3 0.0 0.0029 16.8 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KZN83911.1 - 0.0023 17.9 0.3 0.19 11.7 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KZN83911.1 - 0.066 12.5 0.0 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 KZN83911.1 - 0.09 12.0 0.0 13 4.9 0.0 2.3 2 0 0 2 2 2 0 Thi4 family MFS_1 PF07690.16 KZN83912.1 - 1.9e-24 86.2 37.8 1.9e-24 86.2 37.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily OSTbeta PF15048.6 KZN83912.1 - 0.16 12.1 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Trp_oprn_chp PF09534.10 KZN83912.1 - 0.21 11.4 0.6 18 5.0 0.0 2.4 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF1129 PF06570.11 KZN83912.1 - 0.34 10.4 3.4 1.5 8.3 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF2838 PF10998.8 KZN83912.1 - 1 9.6 10.4 0.033 14.4 2.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2838) Sarcolipin PF05366.11 KZN83912.1 - 4.5 7.0 7.3 38 4.1 1.8 3.5 3 0 0 3 3 3 0 Sarcolipin Lactamase_B PF00753.27 KZN83913.1 - 1.6e-10 41.3 0.2 2.6e-10 40.6 0.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KZN83913.1 - 0.029 13.9 0.0 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 Beta-lactamase superfamily domain HNHc_6 PF16784.5 KZN83913.1 - 0.18 11.3 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative HNHc nuclease ADH_N PF08240.12 KZN83914.1 - 4.1e-22 78.1 1.0 7.1e-22 77.4 1.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN83914.1 - 3.2e-18 66.0 0.0 5.6e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KZN83914.1 - 1.8e-08 35.5 0.0 4.5e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KZN83914.1 - 0.0011 18.3 0.1 0.0018 17.6 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KZN83914.1 - 0.092 12.1 0.0 0.24 10.8 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 KZN83915.1 - 2.2e-29 102.3 0.0 3.2e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN83915.1 - 2.6e-24 86.1 0.0 3.7e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN83915.1 - 2.2e-08 34.2 0.0 2.1e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 KZN83915.1 - 0.015 14.8 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Aa_trans PF01490.18 KZN83916.1 - 4.1e-27 94.9 33.0 5.3e-27 94.6 33.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 KZN83916.1 - 1.1e-06 27.8 41.8 5e-05 22.3 41.8 2.2 1 1 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 KZN83917.1 - 7.6e-14 51.4 20.5 4.1e-13 49.0 15.6 2.7 2 1 0 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KZN83917.1 - 0.014 14.3 1.3 0.023 13.6 1.3 1.4 1 0 0 1 1 1 0 MFS_1 like family Ank_2 PF12796.7 KZN83919.1 - 1.3e-24 86.6 0.4 7.6e-08 32.8 0.2 4.6 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN83919.1 - 1.5e-21 76.4 1.6 0.015 15.8 0.0 6.3 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN83919.1 - 5.6e-17 60.1 3.0 0.032 14.8 0.0 8.8 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 KZN83919.1 - 5.5e-13 48.9 2.4 0.00014 22.0 0.0 4.9 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KZN83919.1 - 3.3e-12 46.2 8.6 0.00075 19.8 0.1 7.0 6 0 0 6 6 6 3 Ankyrin repeat Helo_like_N PF17111.5 KZN83919.1 - 1.4e-05 24.6 3.7 2.2e-05 23.9 3.7 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 KZN83919.1 - 2.5e-05 24.5 0.8 2.5e-05 24.5 0.8 1.8 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases GDPD PF03009.17 KZN83920.1 - 9.4e-50 169.7 0.0 1.7e-49 168.9 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 KZN83920.1 - 7.3e-23 81.0 0.4 1.2e-09 38.6 0.0 4.4 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN83920.1 - 5.5e-09 36.4 2.7 0.22 12.1 0.0 4.7 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN83920.1 - 1.1e-08 34.6 3.3 0.096 13.3 0.0 6.0 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 KZN83920.1 - 3.8e-07 30.2 0.7 2.6 8.6 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KZN83920.1 - 0.00022 21.4 0.0 0.54 10.6 0.0 3.6 2 1 2 4 4 4 2 Ankyrin repeats (many copies) SPX PF03105.19 KZN83920.1 - 0.001 19.1 0.0 0.021 14.7 0.0 2.2 2 0 0 2 2 2 1 SPX domain Syntaxin-6_N PF09177.11 KZN83920.1 - 0.071 13.7 0.8 1.8 9.2 0.5 2.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Beta_elim_lyase PF01212.21 KZN83921.1 - 9.3e-82 274.6 0.0 1.1e-81 274.4 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Catalase PF00199.19 KZN83922.1 - 7.7e-174 578.3 0.0 9.1e-174 578.0 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KZN83922.1 - 8.3e-11 41.9 0.0 2.2e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive GMC_oxred_N PF00732.19 KZN83923.1 - 5.8e-53 180.2 0.0 7.5e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KZN83923.1 - 2.1e-33 115.8 0.0 3.2e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 KZN83923.1 - 0.0021 17.3 0.2 0.0052 16.1 0.1 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 KZN83923.1 - 0.0036 16.6 0.0 0.68 9.1 0.0 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KZN83923.1 - 0.0088 15.1 0.2 0.016 14.3 0.1 1.4 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 KZN83923.1 - 0.017 14.7 0.2 0.035 13.7 0.2 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KZN83923.1 - 0.024 13.7 0.3 0.21 10.6 0.3 2.0 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 KZN83923.1 - 0.061 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN83923.1 - 0.063 13.5 0.4 0.2 11.9 0.4 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain MFS_1 PF07690.16 KZN83924.1 - 9.7e-52 176.0 25.5 9.7e-52 176.0 25.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN83924.1 - 1.3e-13 50.7 2.8 1.3e-13 50.7 2.8 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 KZN83924.1 - 1.2e-06 28.2 6.7 1.2e-06 28.2 6.7 2.2 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 KZN83924.1 - 5.3e-06 25.1 2.0 1e-05 24.2 2.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FPN1 PF06963.12 KZN83924.1 - 0.0047 15.5 0.0 0.0077 14.8 0.0 1.3 1 0 0 1 1 1 1 Ferroportin1 (FPN1) STT3 PF02516.14 KZN83924.1 - 0.19 10.6 8.0 0.36 9.7 0.3 3.0 2 1 1 3 3 3 0 Oligosaccharyl transferase STT3 subunit Gpr1_Fun34_YaaH PF01184.19 KZN83926.1 - 1.6e-43 148.8 19.4 2e-43 148.4 19.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Pkinase PF00069.25 KZN83928.1 - 2.5e-21 76.2 0.0 2.4e-20 73.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN83928.1 - 1.3e-09 37.7 0.0 0.0024 17.2 0.0 3.1 3 1 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KZN83928.1 - 0.0074 15.1 0.0 0.011 14.5 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KZN83928.1 - 0.012 15.2 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KZN83928.1 - 0.014 15.4 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KZN83928.1 - 0.061 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NAD_binding_10 PF13460.6 KZN83929.1 - 1.8e-15 57.3 0.0 3e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KZN83929.1 - 1e-14 54.7 0.0 1.3e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KZN83929.1 - 8.5e-08 31.9 0.2 2.8e-05 23.7 0.2 2.3 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KZN83929.1 - 0.00025 21.5 0.1 0.00059 20.3 0.1 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KZN83929.1 - 0.00058 20.0 0.3 0.0019 18.3 0.3 1.9 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.18 KZN83929.1 - 0.0033 17.7 0.3 0.0065 16.7 0.3 1.5 1 0 0 1 1 1 1 TrkA-N domain RmlD_sub_bind PF04321.17 KZN83929.1 - 0.015 14.4 0.2 0.023 13.8 0.2 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain KR PF08659.10 KZN83929.1 - 0.018 15.0 0.1 0.028 14.3 0.1 1.2 1 0 0 1 1 1 0 KR domain PglD_N PF17836.1 KZN83929.1 - 0.024 15.2 0.1 0.1 13.2 0.1 2.0 2 0 0 2 2 2 0 PglD N-terminal domain DXP_reductoisom PF02670.16 KZN83929.1 - 0.027 15.2 0.2 0.065 14.0 0.2 1.6 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Polysacc_synt_2 PF02719.15 KZN83929.1 - 0.043 12.9 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KZN83929.1 - 0.12 11.3 0.2 0.25 10.3 0.2 1.4 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KZN83929.1 - 0.17 11.3 0.2 0.27 10.6 0.2 1.4 1 0 0 1 1 1 0 short chain dehydrogenase SseC PF04888.12 KZN83930.1 - 0.00077 19.1 9.4 0.00092 18.9 9.4 1.0 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family baeRF_family10 PF18854.1 KZN83930.1 - 0.0028 17.9 7.2 0.0034 17.6 7.2 1.1 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 DUF3464 PF11947.8 KZN83930.1 - 0.023 14.4 3.8 0.026 14.3 3.8 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 COXG PF06240.13 KZN83930.1 - 0.1 12.3 1.8 0.45 10.3 1.6 1.9 1 1 1 2 2 2 0 Carbon monoxide dehydrogenase subunit G (CoxG) PRTP PF01366.18 KZN83930.1 - 0.15 10.0 4.0 0.17 9.9 4.0 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Herpes_BLRF2 PF05812.12 KZN83930.1 - 0.18 12.0 6.7 0.27 11.4 6.7 1.4 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein Cu PF17563.2 KZN83930.1 - 0.39 10.9 34.4 1.8e+04 -18.3 34.4 4.8 1 1 0 1 1 0 0 Cupiennin VSG_B PF13206.6 KZN83930.1 - 0.78 8.9 7.0 0.9 8.7 7.0 1.0 1 0 0 1 1 1 0 Trypanosomal VSG domain Syntaxin-18_N PF10496.9 KZN83930.1 - 2.4 8.5 6.2 3.6 7.9 6.2 1.4 1 1 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus DUF5455 PF17537.2 KZN83930.1 - 3.1 8.3 6.4 13 6.3 1.2 2.8 1 1 1 2 2 2 0 Family of unknown function (DUF5455) CelTOS PF18659.1 KZN83930.1 - 3.4 8.1 6.5 13 6.3 6.5 1.9 1 1 0 1 1 1 0 Cell-traversal protein for ookinetes and sporozoites HK97-gp10_like PF04883.12 KZN83930.1 - 3.5 8.7 19.1 3.8e+02 2.1 19.1 2.1 1 1 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component GCN5L1 PF06320.13 KZN83930.1 - 4 7.6 10.1 7.9 6.7 10.1 1.5 1 1 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Choline_kinase PF01633.20 KZN83932.1 - 1.4e-22 80.4 0.2 3.5e-22 79.0 0.0 1.6 1 1 1 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 KZN83932.1 - 4.6e-05 23.5 0.0 6.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DDE_Tnp_2 PF04693.12 KZN83932.1 - 0.054 12.7 0.1 0.073 12.3 0.1 1.1 1 0 0 1 1 1 0 Archaeal putative transposase ISC1217 EcKinase PF02958.20 KZN83932.1 - 0.069 12.5 0.0 0.098 11.9 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase_fungal PF17667.1 KZN83932.1 - 0.13 11.0 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Sugar_tr PF00083.24 KZN83933.1 - 3e-93 313.1 13.8 3.5e-93 312.9 13.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN83933.1 - 5.8e-32 111.0 28.7 1.6e-27 96.4 20.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KZN83933.1 - 0.0018 16.8 4.6 0.005 15.3 0.5 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KZN83933.1 - 0.0025 16.5 19.1 0.0052 15.4 0.8 3.4 2 2 1 3 3 3 3 MFS/sugar transport protein OATP PF03137.20 KZN83933.1 - 0.053 11.8 3.9 0.078 11.2 0.9 2.5 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family RUN PF02759.19 KZN83933.1 - 0.098 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 RUN domain DUF3792 PF12670.7 KZN83933.1 - 3.3 7.9 19.2 0.27 11.4 7.1 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF3792) Fungal_trans PF04082.18 KZN83934.1 - 4.7e-11 42.2 0.0 9.1e-11 41.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain CorA PF01544.18 KZN83935.1 - 8e-33 114.0 0.0 1e-32 113.7 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 KZN83935.1 - 0.22 10.2 0.3 0.26 10.0 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Peptidase_A4 PF01828.17 KZN83936.1 - 1.5e-82 276.1 10.7 1.8e-82 275.9 10.7 1.1 1 0 0 1 1 1 1 Peptidase A4 family MF_alpha_N PF05436.11 KZN83936.1 - 0.19 11.7 0.3 0.37 10.7 0.3 1.5 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus LysM PF01476.20 KZN83937.1 - 5e-06 26.5 0.1 1.3e-05 25.2 0.1 1.7 1 0 0 1 1 1 1 LysM domain Chitin_bind_1 PF00187.19 KZN83937.1 - 0.00095 19.6 15.6 0.00095 19.6 15.6 2.8 2 1 0 2 2 2 1 Chitin recognition protein DUF3094 PF11293.8 KZN83938.1 - 0.84 9.4 4.9 1.8 8.4 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) GMC_oxred_C PF05199.13 KZN83939.1 - 2.4e-27 96.2 0.1 9.7e-27 94.3 0.0 2.1 2 1 0 2 2 2 1 GMC oxidoreductase Sugar_tr PF00083.24 KZN83940.1 - 1.9e-82 277.6 21.5 2.3e-82 277.2 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN83940.1 - 3.6e-16 59.0 48.0 1.2e-14 54.1 26.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Lipoprotein_Ltp PF07553.11 KZN83940.1 - 2.2 8.6 4.2 3.1 8.1 1.0 2.3 2 0 0 2 2 2 0 Host cell surface-exposed lipoprotein Acetyltransf_10 PF13673.7 KZN83942.1 - 4.9e-13 49.1 0.0 7.4e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KZN83942.1 - 5.1e-13 49.3 0.1 8.6e-13 48.5 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KZN83942.1 - 1.7e-10 41.2 0.1 3.4e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KZN83942.1 - 0.0038 17.3 0.0 0.0068 16.5 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KZN83942.1 - 0.0096 16.0 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain tRNA-synt_2b PF00587.25 KZN83943.1 - 5.3e-28 98.2 0.0 1e-26 94.0 0.0 2.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KZN83943.1 - 1.9e-11 44.0 0.0 5.1e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain CBF PF03914.17 KZN83944.1 - 8.5e-56 188.6 2.6 1.3e-55 188.1 0.1 2.7 3 0 0 3 3 3 1 CBF/Mak21 family Prok-E2_C PF14459.6 KZN83944.1 - 0.21 11.8 0.0 0.42 10.8 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family C Aa_trans PF01490.18 KZN83945.1 - 2.4e-23 82.5 36.4 3.1e-23 82.1 36.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein GCV_T PF01571.21 KZN83946.1 - 7.8e-79 264.7 0.0 1e-78 264.3 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KZN83946.1 - 1.1e-15 57.3 0.4 2.6e-15 56.1 0.4 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain LVIVD PF08309.11 KZN83946.1 - 0.017 14.4 0.1 0.032 13.5 0.1 1.5 1 0 0 1 1 1 0 LVIVD repeat DUF3336 PF11815.8 KZN83951.1 - 1.9e-35 121.6 1.1 3.3e-35 120.8 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KZN83951.1 - 4.6e-21 75.9 0.0 8.8e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Abhydrolase_6 PF12697.7 KZN83952.1 - 0.0018 18.9 0.1 0.0028 18.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.22 KZN83952.1 - 0.012 15.5 0.0 0.087 12.8 0.0 2.0 2 0 0 2 2 2 0 Cutinase Hydrolase_4 PF12146.8 KZN83952.1 - 0.14 11.4 0.4 12 5.1 0.0 2.6 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KZN83952.1 - 0.17 11.4 0.4 0.65 9.4 0.0 2.1 3 0 0 3 3 3 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KZN83952.1 - 0.31 10.7 1.4 5.2 6.6 0.8 2.6 1 1 0 2 2 2 0 alpha/beta hydrolase fold Fez1 PF06818.15 KZN83953.1 - 0.00019 22.0 5.8 0.00036 21.1 5.8 1.4 1 0 0 1 1 1 1 Fez1 Seryl_tRNA_N PF02403.22 KZN83953.1 - 0.0012 19.0 6.4 0.0034 17.6 3.9 2.5 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Phage_GP20 PF06810.11 KZN83953.1 - 0.018 14.8 2.9 0.046 13.5 2.9 1.6 1 0 0 1 1 1 0 Phage minor structural protein GP20 RPW8 PF05659.11 KZN83953.1 - 0.032 13.9 1.4 1.7 8.4 0.3 2.7 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 FliD_C PF07195.12 KZN83953.1 - 0.07 12.5 1.1 2.3 7.6 0.1 2.7 2 2 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Vac_Fusion PF02346.16 KZN83953.1 - 0.074 12.7 1.5 1.8 8.2 0.1 2.7 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 TMCO5 PF14992.6 KZN83953.1 - 0.097 12.2 8.9 0.032 13.8 3.9 2.1 2 0 0 2 2 2 0 TMCO5 family DUF724 PF05266.14 KZN83953.1 - 0.098 12.5 6.8 0.29 10.9 2.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF724) Noelin-1 PF12308.8 KZN83953.1 - 0.1 12.6 1.3 0.24 11.4 0.4 2.1 2 0 0 2 2 1 0 Neurogenesis glycoprotein DUF3189 PF11385.8 KZN83953.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3189) DUF2730 PF10805.8 KZN83953.1 - 0.13 12.4 0.5 0.49 10.5 0.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) SLX9 PF15341.6 KZN83953.1 - 0.14 12.6 1.3 0.32 11.4 1.3 1.7 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 DUF3450 PF11932.8 KZN83953.1 - 0.22 10.8 3.8 0.57 9.4 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 KZN83953.1 - 0.24 11.4 4.7 0.7 9.9 0.7 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) HSP70 PF00012.20 KZN83953.1 - 0.26 9.4 2.0 0.38 8.9 2.0 1.2 1 0 0 1 1 1 0 Hsp70 protein CLZ PF16526.5 KZN83953.1 - 0.28 11.6 10.4 0.061 13.7 1.2 3.5 4 0 0 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TMF_DNA_bd PF12329.8 KZN83953.1 - 0.3 11.1 8.2 0.15 12.0 3.8 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.10 KZN83953.1 - 0.3 11.3 5.3 1.4 9.1 2.0 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Paralemmin PF03285.15 KZN83953.1 - 0.32 10.6 8.6 0.32 10.5 4.4 2.4 2 1 0 2 2 2 0 Paralemmin ABC_tran_CTD PF16326.5 KZN83953.1 - 0.37 11.1 8.1 0.94 9.8 2.8 3.3 2 1 0 3 3 3 0 ABC transporter C-terminal domain Baculo_PEP_C PF04513.12 KZN83953.1 - 0.37 10.8 2.4 0.78 9.8 1.1 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.11 KZN83953.1 - 0.51 10.8 6.3 0.39 11.1 0.7 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Syntaxin-6_N PF09177.11 KZN83953.1 - 0.79 10.3 6.9 14 6.3 4.0 3.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal COG5 PF10392.9 KZN83953.1 - 1 9.5 10.2 0.3 11.3 3.0 3.1 3 0 0 3 3 3 0 Golgi transport complex subunit 5 LMBR1 PF04791.16 KZN83953.1 - 1.1 8.1 2.5 1.4 7.7 2.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4472 PF14739.6 KZN83953.1 - 1.7 9.4 9.3 0.87 10.4 2.3 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF4472) DUF4164 PF13747.6 KZN83953.1 - 8.9 6.7 12.1 1.3 9.4 4.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) RPN2_C PF18004.1 KZN83954.1 - 7e-57 191.8 7.3 7e-57 191.8 7.3 2.7 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KZN83954.1 - 3.5e-36 121.8 18.1 7.9e-10 38.7 0.1 8.2 7 0 0 7 7 7 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KZN83954.1 - 4.9e-22 78.1 0.1 1.8e-14 53.9 0.0 4.7 3 1 0 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 KZN83954.1 - 2.6e-06 27.8 0.1 0.001 19.5 0.0 4.9 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.22 KZN83954.1 - 5.3e-05 23.1 0.0 12 6.4 0.0 5.1 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 KZN83954.1 - 0.0043 17.1 0.7 0.26 11.3 0.0 3.0 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 KZN83954.1 - 0.027 15.1 2.1 1.1 10.2 0.0 4.2 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Acyl-CoA_dh_1 PF00441.24 KZN83955.1 - 4.2e-41 140.6 0.3 6e-41 140.1 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KZN83955.1 - 6.7e-22 77.5 0.1 1.2e-21 76.7 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KZN83955.1 - 8.5e-20 71.5 0.0 1.9e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.28 KZN83955.1 - 1.5e-14 53.9 0.1 3.1e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.11 KZN83955.1 - 3.7e-08 33.7 0.0 5.8e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain C6 PF01681.17 KZN83955.1 - 0.18 12.4 0.3 0.49 11.0 0.1 1.9 2 0 0 2 2 2 0 C6 domain DEC-1_N PF04625.13 KZN83955.1 - 7.1 5.5 6.5 12 4.8 6.5 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region CTD PF12815.7 KZN83956.1 - 3e-22 78.9 27.4 9.9e-19 67.7 19.3 3.8 1 1 2 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.8 KZN83956.1 - 1.1e-17 64.9 11.2 1.1e-17 64.9 11.2 3.8 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal Spt5-NGN PF03439.13 KZN83956.1 - 6.1e-17 61.3 0.0 1e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 KZN83956.1 - 6.7e-11 41.7 12.6 0.0037 17.2 0.4 4.2 4 0 0 4 4 4 3 KOW motif DUF3912 PF13051.6 KZN83956.1 - 0.0048 17.1 0.4 2.4 8.5 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3912) TFIIF_alpha PF05793.12 KZN83956.1 - 2.2 6.8 39.1 3.1 6.3 39.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Amidase PF01425.21 KZN83957.1 - 4.5e-101 339.0 0.0 1.5e-100 337.3 0.0 1.7 1 1 0 1 1 1 1 Amidase DAO PF01266.24 KZN83958.1 - 6.5e-33 114.8 2.5 7.6e-33 114.5 2.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KZN83958.1 - 0.0026 17.9 0.5 0.012 15.8 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KZN83958.1 - 0.0052 16.8 0.1 0.44 10.5 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KZN83958.1 - 0.046 12.9 0.0 0.079 12.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RhoGAP-FF1 PF16512.5 KZN83958.1 - 0.16 12.7 0.0 0.32 11.7 0.0 1.4 1 0 0 1 1 1 0 p190-A and -B Rho GAPs FF domain DUF4623 PF15416.6 KZN83958.1 - 0.23 10.0 0.0 0.34 9.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4623) MFS_1 PF07690.16 KZN83959.1 - 1.6e-36 126.0 15.4 1.6e-36 126.0 15.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN83959.1 - 7.1e-11 41.6 3.5 7.1e-11 41.6 3.5 3.5 3 1 2 5 5 5 1 Sugar (and other) transporter Gly-zipper_Omp PF13488.6 KZN83959.1 - 1.3 9.1 5.2 0.67 10.0 0.4 2.5 2 0 0 2 2 2 0 Glycine zipper Zn_clus PF00172.18 KZN83960.1 - 1.2e-08 34.9 11.1 2.6e-08 33.8 11.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain mRNA_triPase PF02940.15 KZN83961.1 - 1.6e-61 207.9 0.1 2.5e-61 207.2 0.1 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain BolA PF01722.18 KZN83961.1 - 0.14 12.4 0.1 0.36 11.1 0.1 1.6 1 0 0 1 1 1 0 BolA-like protein ParB_C PF18064.1 KZN83961.1 - 0.15 12.3 0.1 0.42 10.8 0.1 1.8 1 0 0 1 1 1 0 Centromere-binding protein ParB C-terminal Acyl_transf_3 PF01757.22 KZN83963.1 - 5e-31 108.0 40.1 9.8e-31 107.0 40.1 1.6 1 1 0 1 1 1 1 Acyltransferase family DUF4395 PF14340.6 KZN83963.1 - 0.01 16.1 4.2 0.061 13.6 0.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4395) UPF0182 PF03699.13 KZN83963.1 - 2.8 6.0 5.4 0.2 9.7 0.5 1.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0182) WD40 PF00400.32 KZN83964.1 - 2.7e-13 50.2 7.3 5.9e-05 23.8 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat CTP_transf_like PF01467.26 KZN83965.1 - 9.4e-06 25.9 0.0 2.9e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 KZN83965.1 - 0.08 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 FAD synthetase F-box-like PF12937.7 KZN83966.1 - 0.078 12.9 0.1 0.39 10.6 0.1 2.2 1 1 0 1 1 1 0 F-box-like His_Phos_2 PF00328.22 KZN83967.1 - 1.7e-75 254.8 0.0 2e-75 254.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Peptidase_M6 PF05547.11 KZN83968.1 - 0.009 14.4 0.7 0.014 13.7 0.7 1.3 1 0 0 1 1 1 1 Immune inhibitor A peptidase M6 Reprolysin_5 PF13688.6 KZN83968.1 - 0.015 15.4 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Trp_ring PF18669.1 KZN83968.1 - 0.069 13.3 2.6 0.16 12.2 1.7 2.1 2 0 0 2 2 2 0 Trimeric autotransporter adhesin Trp ring domain Cep57_MT_bd PF06657.13 KZN83970.1 - 6e-30 103.5 0.1 6e-30 103.5 0.1 5.0 5 1 1 6 6 6 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 KZN83970.1 - 1.7e-19 69.7 11.1 1.7e-19 69.7 11.1 4.7 5 0 0 5 5 5 1 Centrosome localisation domain of PPC89 HALZ PF02183.18 KZN83970.1 - 3 8.2 9.9 0.2 11.9 0.9 3.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper Spore_III_AB PF09548.10 KZN83970.1 - 3.8 7.6 5.1 0.84 9.7 0.1 2.5 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) FlaC_arch PF05377.11 KZN83970.1 - 7.3 7.1 9.9 13 6.2 0.1 5.3 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) MAT1 PF06391.13 KZN83971.1 - 5.1e-42 144.0 15.4 7.4e-42 143.5 15.4 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KZN83971.1 - 2.3e-32 110.6 8.6 3.6e-32 110.0 8.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KZN83971.1 - 5.7e-05 22.9 5.5 0.00011 22.0 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KZN83971.1 - 0.00034 20.4 3.8 0.00073 19.3 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KZN83971.1 - 0.00042 20.1 5.1 0.0016 18.3 5.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KZN83971.1 - 0.0015 18.9 6.1 0.0026 18.1 6.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 KZN83971.1 - 0.0049 16.6 6.6 0.036 13.9 1.9 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 KZN83971.1 - 0.0053 16.4 1.4 0.011 15.3 1.4 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KZN83971.1 - 0.011 15.7 7.8 0.12 12.3 8.3 2.1 1 1 1 2 2 2 0 zinc-RING finger domain DUF3797 PF12677.7 KZN83971.1 - 0.05 13.5 2.4 0.15 12.0 2.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) zf-RING_UBOX PF13445.6 KZN83971.1 - 0.21 11.6 6.0 0.43 10.6 6.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 KZN83971.1 - 0.67 9.9 7.9 16 5.4 8.7 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Nup88 PF10168.9 KZN83971.1 - 1.2 6.9 6.5 1.7 6.3 6.5 1.2 1 0 0 1 1 1 0 Nuclear pore component Prefoldin_3 PF13758.6 KZN83972.1 - 1.8e-36 124.2 0.5 3.9e-36 123.1 0.5 1.6 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.7 KZN83972.1 - 5.5e-16 59.2 2.2 5.5e-16 59.2 2.2 5.3 4 2 1 5 5 5 2 Domain of unknown function (DUF3835) Prefoldin PF02996.17 KZN83972.1 - 0.014 15.3 0.2 0.05 13.5 0.2 2.0 1 0 0 1 1 1 0 Prefoldin subunit CCDC-167 PF15188.6 KZN83972.1 - 0.25 11.7 2.9 14 6.1 0.2 2.9 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Prefoldin_2 PF01920.20 KZN83972.1 - 1.4 8.9 5.5 2.1 8.3 0.2 3.3 2 1 1 3 3 3 0 Prefoldin subunit adh_short PF00106.25 KZN83973.1 - 2.8e-15 56.3 0.1 3.6e-14 52.7 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN83973.1 - 1.2e-05 25.0 0.0 2.8e-05 23.8 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN83973.1 - 8.1e-05 22.6 0.1 0.00015 21.8 0.1 1.4 1 0 0 1 1 1 1 KR domain Fungal_trans PF04082.18 KZN83974.1 - 2.4e-12 46.5 0.0 4.8e-12 45.5 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN83974.1 - 0.14 12.3 4.8 0.33 11.1 4.8 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KZN83975.1 - 5.2e-43 147.3 0.0 1.9e-42 145.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN83975.1 - 4.4e-29 101.5 0.0 6.5e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KZN83975.1 - 0.00015 20.6 0.0 0.00025 20.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KZN83975.1 - 0.00027 20.3 0.0 0.00078 18.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KZN83975.1 - 0.00054 19.4 0.1 0.0015 17.9 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KZN83975.1 - 0.0018 18.3 1.5 0.025 14.5 0.4 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family Ank_2 PF12796.7 KZN83976.1 - 2.8e-06 27.8 0.0 7.9e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) NACHT PF05729.12 KZN83976.1 - 4.8e-06 26.6 0.2 2.7e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 NACHT domain Ank_4 PF13637.6 KZN83976.1 - 6.9e-06 26.5 0.0 0.00039 20.9 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) AAA_16 PF13191.6 KZN83976.1 - 2.1e-05 24.9 0.0 8.5e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain Helo_like_N PF17111.5 KZN83976.1 - 0.00031 20.2 5.2 0.0012 18.2 5.1 2.1 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins NB-ARC PF00931.22 KZN83976.1 - 0.00064 19.0 0.0 0.0019 17.4 0.0 1.8 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KZN83976.1 - 0.0021 18.3 0.1 0.025 14.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain Ank_3 PF13606.6 KZN83976.1 - 0.0031 17.9 0.0 8.4 7.3 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat AAA_14 PF13173.6 KZN83976.1 - 0.0036 17.3 0.1 0.082 12.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain Ank_5 PF13857.6 KZN83976.1 - 0.01 16.1 0.0 1.2 9.6 0.0 2.7 1 1 1 2 2 2 0 Ankyrin repeats (many copies) AAA PF00004.29 KZN83976.1 - 0.012 16.1 0.4 0.062 13.7 0.4 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KZN83976.1 - 0.013 15.5 0.1 0.043 13.7 0.1 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Ank PF00023.30 KZN83976.1 - 0.034 14.6 0.0 5.8 7.6 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat AAA_33 PF13671.6 KZN83976.1 - 0.061 13.5 0.1 0.24 11.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KZN83976.1 - 0.11 12.3 0.3 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 KZN83976.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NGP1NT PF08153.12 KZN83977.1 - 9.5e-49 164.9 0.2 1.5e-48 164.3 0.2 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KZN83977.1 - 6.3e-17 61.7 0.0 3.4e-13 49.7 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KZN83977.1 - 1.3e-05 24.8 0.0 0.0001 21.9 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 KZN83977.1 - 0.00031 20.3 0.0 0.12 11.8 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Dynamin_N PF00350.23 KZN83977.1 - 0.00036 20.7 0.1 0.32 11.0 0.1 3.4 2 1 1 3 3 3 1 Dynamin family RsgA_GTPase PF03193.16 KZN83977.1 - 0.0012 18.8 0.0 0.0034 17.3 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase Roc PF08477.13 KZN83977.1 - 0.042 14.1 0.0 13 6.0 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KZN83977.1 - 0.092 12.3 0.0 5.3 6.5 0.0 2.9 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain DUF2462 PF09495.10 KZN83979.1 - 3.1e-21 75.9 3.7 3.1e-21 75.9 3.7 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) Zn_clus PF00172.18 KZN83980.1 - 0.0038 17.3 9.9 0.0084 16.2 9.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_helicase PF00910.22 KZN83980.1 - 0.092 13.1 0.2 1.3 9.4 0.1 2.7 3 0 0 3 3 3 0 RNA helicase BAALC_N PF06989.12 KZN83980.1 - 9.5 6.6 6.5 8.1 6.9 0.1 3.3 3 0 0 3 3 3 0 BAALC N-terminus SurE PF01975.17 KZN83981.1 - 6.8e-53 179.3 0.0 8.6e-53 179.0 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE DUF5427 PF10310.9 KZN83982.1 - 1.5e-167 558.3 0.3 1.8e-167 558.0 0.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Flu_M1_C PF08289.11 KZN83982.1 - 0.13 12.5 0.3 0.13 12.5 0.3 2.0 2 1 1 3 3 3 0 Influenza Matrix protein (M1) C-terminal domain DUF2020 PF09449.10 KZN83982.1 - 0.35 10.7 4.7 1.5 8.6 2.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2020) SARAF PF06682.12 KZN83982.1 - 0.55 9.8 5.9 0.87 9.2 5.9 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CMD PF02627.20 KZN83983.1 - 3.4e-07 30.2 0.1 6.5e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family CARD_2 PF16739.5 KZN83983.1 - 0.16 11.9 0.0 1.8 8.6 0.0 2.1 1 1 1 2 2 2 0 Caspase recruitment domain zf-C2H2_12 PF18658.1 KZN83984.1 - 0.069 12.7 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 Zinc-finger C2H2-type DBINO PF13892.6 KZN83984.1 - 2.4 8.5 8.5 0.39 11.1 0.9 2.9 3 0 0 3 3 3 0 DNA-binding domain zf-C2H2_4 PF13894.6 KZN83985.1 - 3.4e-06 27.4 1.9 0.055 14.3 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KZN83985.1 - 0.0012 19.2 3.0 0.055 13.9 0.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KZN83985.1 - 0.15 12.1 1.1 0.58 10.2 0.4 2.3 1 1 1 2 2 2 0 C2H2-type zinc finger DUF629 PF04780.12 KZN83985.1 - 0.21 10.1 0.0 0.29 9.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-Di19 PF05605.12 KZN83985.1 - 0.23 11.8 1.2 7 7.0 0.6 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Tmemb_14 PF03647.13 KZN83986.1 - 5.2e-19 68.8 10.0 6e-19 68.6 10.0 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C TFR_dimer PF04253.15 KZN83987.1 - 4.9e-26 91.2 0.0 7.6e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KZN83987.1 - 1.1e-20 74.2 0.0 1.7e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KZN83987.1 - 6.9e-09 35.6 0.1 1.9e-08 34.2 0.1 1.7 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.15 KZN83987.1 - 0.0041 16.6 0.0 0.0074 15.8 0.0 1.3 1 0 0 1 1 1 1 Nicastrin RTC4 PF14474.6 KZN83988.1 - 4.4e-31 107.6 0.0 7.8e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain DUF726 PF05277.12 KZN83989.1 - 1.2e-127 425.6 3.2 1.8e-127 425.0 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Glyco_hydro_18 PF00704.28 KZN83989.1 - 8.6e-73 245.8 1.0 1.4e-72 245.0 1.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KZN83989.1 - 1.7e-17 63.6 44.5 1.3e-12 47.9 16.2 2.4 2 0 0 2 2 2 2 Chitin recognition protein Pyr_redox_2 PF07992.14 KZN83991.1 - 1.5e-44 152.4 0.5 2.9e-44 151.5 0.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 KZN83991.1 - 5.2e-22 78.0 0.0 1.4e-21 76.7 0.0 1.7 2 0 0 2 2 2 1 Nitrite and sulphite reductase 4Fe-4S domain Rieske_2 PF13806.6 KZN83991.1 - 2.1e-16 59.7 0.0 4.3e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Pyr_redox PF00070.27 KZN83991.1 - 1.6e-15 57.4 5.8 7.2e-15 55.3 0.6 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 KZN83991.1 - 2.6e-14 53.3 9.8 1.7e-12 47.5 5.9 2.9 3 0 0 3 3 3 2 BFD-like [2Fe-2S] binding domain Rieske PF00355.26 KZN83991.1 - 3.3e-14 52.6 0.3 1.7e-13 50.3 0.0 2.3 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.17 KZN83991.1 - 8.2e-11 41.6 0.0 1.7e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 KZN83991.1 - 3.5e-06 26.8 0.4 0.013 15.4 0.0 3.1 3 0 0 3 3 3 2 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 KZN83991.1 - 0.00057 19.9 0.5 2.4 8.1 0.1 3.2 3 1 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KZN83991.1 - 0.041 13.0 0.2 0.11 11.5 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 KZN83991.1 - 0.084 13.3 0.1 1.4 9.4 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Ribonuc_L-PSP PF01042.21 KZN83992.1 - 8.9e-24 83.8 0.0 1e-23 83.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP MFS_1 PF07690.16 KZN83993.1 - 8.7e-28 97.2 26.4 8.7e-28 97.2 26.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily rhaM PF05336.13 KZN83994.1 - 7.4e-38 128.9 0.2 8.4e-38 128.8 0.2 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase Bmp PF02608.14 KZN83994.1 - 0.12 11.3 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 ABC transporter substrate-binding protein PnrA-like Abhydrolase_1 PF00561.20 KZN83996.1 - 1.9e-19 70.3 0.6 4.7e-19 69.0 0.6 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KZN83996.1 - 2e-16 61.3 2.6 2.6e-16 60.9 2.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KZN83996.1 - 7.8e-16 58.1 0.0 1.9e-15 56.8 0.1 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 KZN83996.1 - 2.2e-05 23.3 0.0 3.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Ndr family PGAP1 PF07819.13 KZN83996.1 - 0.00021 21.1 0.0 0.0003 20.6 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.7 KZN83996.1 - 0.00065 19.5 0.1 0.0017 18.1 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 KZN83996.1 - 0.0018 17.6 0.1 0.003 16.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Say1_Mug180 PF10340.9 KZN83996.1 - 0.0037 16.2 0.0 0.0055 15.6 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Esterase PF00756.20 KZN83996.1 - 0.0044 16.7 0.1 0.0089 15.7 0.1 1.5 1 0 0 1 1 1 1 Putative esterase Eno-Rase_NADH_b PF12242.8 KZN83996.1 - 0.016 14.9 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase UPF0227 PF05728.12 KZN83996.1 - 0.039 13.9 0.1 0.063 13.2 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_2 PF02230.16 KZN83996.1 - 0.13 12.0 0.2 2.2 8.0 0.1 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase TauD PF02668.16 KZN83997.1 - 1.5e-20 74.1 0.8 2e-16 60.6 0.5 2.1 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family FhuF PF06276.12 KZN83998.1 - 7e-20 72.1 0.0 1.3e-19 71.2 0.0 1.5 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter IucA_IucC PF04183.12 KZN83998.1 - 5.8e-19 68.6 0.2 1.1e-15 57.9 0.0 2.4 2 0 0 2 2 2 2 IucA / IucC family DUF3562 PF12085.8 KZN83998.1 - 0.092 12.4 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) adh_short PF00106.25 KZN83999.1 - 6.1e-21 74.8 0.0 4.8e-18 65.3 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KZN83999.1 - 2e-11 43.9 0.0 1.6e-10 41.0 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN83999.1 - 4.6e-05 23.4 0.0 6.3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KZN83999.1 - 0.049 14.2 0.1 0.21 12.2 0.1 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Tugs PF17840.1 KZN84000.1 - 1.9 8.7 6.2 1 9.6 0.1 3.4 3 0 0 3 3 3 0 Tethering Ubl4a to BAGS domain FlgM PF04316.13 KZN84000.1 - 2.2 8.7 5.8 13 6.3 0.4 3.6 3 0 0 3 3 3 0 Anti-sigma-28 factor, FlgM SOG2 PF10428.9 KZN84001.1 - 0.62 9.2 7.7 0.69 9.0 7.7 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein CC190 PF15768.5 KZN84001.1 - 0.82 9.7 3.9 1 9.4 3.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 ORC6 PF05460.13 KZN84001.1 - 1.1 8.4 5.8 1.3 8.2 5.8 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Ribosomal_L5e PF17144.4 KZN84002.1 - 9.3e-83 276.1 0.3 1.5e-82 275.4 0.3 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KZN84002.1 - 2.1e-32 111.9 7.9 2.1e-32 111.9 7.9 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region HAD_2 PF13419.6 KZN84003.1 - 1.9e-07 31.4 0.0 2.9e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KZN84003.1 - 4.5e-06 26.6 0.0 7.5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KZN84003.1 - 0.0047 17.2 0.0 0.0058 16.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FTA4 PF13093.6 KZN84004.1 - 1.9e-62 210.8 4.5 2.2e-62 210.5 4.5 1.0 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF4477 PF14780.6 KZN84004.1 - 0.073 12.7 0.4 0.44 10.1 0.0 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4477) PAP_central PF04928.17 KZN84004.1 - 0.14 11.2 1.2 0.15 11.0 0.5 1.4 2 0 0 2 2 2 0 Poly(A) polymerase central domain Seryl_tRNA_N PF02403.22 KZN84004.1 - 0.56 10.5 5.4 1.3 9.3 2.6 2.7 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FUSC PF04632.12 KZN84004.1 - 0.76 8.2 2.6 0.87 8.0 2.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cortex-I_coil PF09304.10 KZN84004.1 - 3.2 8.0 9.0 0.71 10.1 4.3 2.2 2 1 1 3 3 3 0 Cortexillin I, coiled coil NUDIX PF00293.28 KZN84005.1 - 9.6e-17 61.3 0.6 1.1e-16 61.0 0.6 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KZN84005.1 - 0.00054 19.9 0.1 0.00099 19.1 0.2 1.4 1 1 0 1 1 1 1 NUDIX domain DegT_DnrJ_EryC1 PF01041.17 KZN84006.1 - 2.1e-56 191.8 0.0 2.5e-54 184.9 0.0 2.1 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KZN84006.1 - 1e-07 31.3 0.0 1.5e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KZN84006.1 - 8e-05 22.0 0.0 0.00021 20.6 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II GFO_IDH_MocA_C PF02894.17 KZN84006.1 - 0.0075 16.3 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain LRR_4 PF12799.7 KZN84008.1 - 0.014 15.8 1.6 5.8 7.5 0.0 5.2 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) ABC_membrane_2 PF06472.15 KZN84009.1 - 7.2e-105 350.2 0.4 1.4e-104 349.3 0.4 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KZN84009.1 - 5.2e-19 69.1 0.0 1e-18 68.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KZN84009.1 - 8.2e-05 22.6 0.0 0.00025 20.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KZN84009.1 - 0.0037 17.8 0.0 0.0093 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KZN84009.1 - 0.021 14.6 0.0 0.06 13.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Reticulon PF02453.17 KZN84009.1 - 0.022 14.7 0.1 0.044 13.7 0.1 1.5 1 0 0 1 1 1 0 Reticulon SMC_N PF02463.19 KZN84009.1 - 0.03 13.7 0.1 0.15 11.5 0.1 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain RuvB_N PF05496.12 KZN84009.1 - 0.068 12.9 0.0 1.3 8.7 0.0 2.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_27 PF13514.6 KZN84009.1 - 0.13 11.8 0.0 0.35 10.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KZN84009.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 KZN84009.1 - 0.16 12.3 0.7 0.93 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_15 PF13175.6 KZN84009.1 - 0.2 11.3 0.1 0.38 10.4 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain HAD PF12710.7 KZN84010.1 - 7.7e-33 114.5 0.0 1.1e-32 114.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KZN84010.1 - 0.00025 20.6 0.0 0.48 9.8 0.0 2.2 2 0 0 2 2 2 2 Putative Phosphatase Hydrolase PF00702.26 KZN84010.1 - 0.0068 16.7 0.0 0.038 14.3 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Phosphorylase PF00343.20 KZN84011.1 - 0 1054.5 0.0 0 1054.3 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase G-alpha PF00503.20 KZN84012.1 - 9.4e-113 377.0 0.2 1.1e-112 376.8 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KZN84012.1 - 5.2e-15 55.3 1.0 3.5e-10 39.6 0.3 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KZN84012.1 - 0.00014 21.3 0.1 0.4 10.0 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KZN84012.1 - 0.0049 17.1 0.3 0.95 9.7 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KZN84012.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 KZN84012.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain Pkinase PF00069.25 KZN84013.1 - 3.8e-67 226.5 0.0 4.9e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN84013.1 - 8.8e-32 110.4 0.0 1.2e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KZN84013.1 - 1.1e-05 24.6 0.1 1.5e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KZN84013.1 - 0.00015 21.2 0.1 0.00053 19.4 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KZN84013.1 - 0.00049 19.5 0.0 0.046 13.0 0.0 2.3 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 KZN84013.1 - 0.001 19.0 0.0 0.0024 17.9 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KZN84013.1 - 0.013 15.1 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KZN84013.1 - 0.046 13.3 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Avl9 PF09794.9 KZN84014.1 - 1.7e-137 458.2 0.0 2.3e-137 457.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 KZN84014.1 - 1.1e-06 28.5 0.1 0.0078 16.2 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 KZN84014.1 - 0.00039 20.1 3.2 0.052 13.1 0.2 3.5 2 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2347) Cullin PF00888.22 KZN84015.1 - 2.6e-191 637.4 11.1 3.6e-191 636.9 11.1 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KZN84015.1 - 9e-27 92.9 5.3 1.4e-26 92.3 3.5 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain Kinase-PPPase PF03618.14 KZN84015.1 - 2.3 7.9 6.7 3.8 7.2 0.4 2.4 2 0 0 2 2 2 0 Kinase/pyrophosphorylase APH PF01636.23 KZN84016.1 - 1.3e-25 90.7 0.2 1.7e-25 90.3 0.2 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN84016.1 - 0.00024 20.8 0.0 0.00038 20.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase PheRS_DBD2 PF18554.1 KZN84016.1 - 0.12 12.4 0.5 0.41 10.7 0.1 2.0 2 0 0 2 2 2 0 PheRS DNA binding domain 2 Cupin_2 PF07883.11 KZN84017.1 - 4.9e-07 29.4 0.5 1.4e-06 27.9 0.1 1.8 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 KZN84017.1 - 4.1e-06 26.5 0.0 6.1e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.14 KZN84017.1 - 0.0011 19.1 0.1 0.0013 18.9 0.1 1.3 1 0 0 1 1 1 1 ARD/ARD' family Cupin_6 PF12852.7 KZN84017.1 - 0.013 15.3 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 Cupin Mit_KHE1 PF10173.9 KZN84019.1 - 5.1e-62 209.4 0.5 9.6e-62 208.5 0.5 1.5 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related End3 PF12761.7 KZN84020.1 - 2.3e-69 233.6 0.5 3.3e-69 233.1 0.5 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 KZN84020.1 - 2.7e-51 171.9 0.3 5.4e-48 161.2 0.2 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KZN84020.1 - 8.9e-08 31.2 0.3 2.6e-07 29.7 0.3 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KZN84020.1 - 8.2e-07 29.4 0.1 4.9e-06 26.9 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KZN84020.1 - 0.00017 21.3 0.1 0.00064 19.5 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KZN84020.1 - 0.0022 17.4 0.2 0.0081 15.6 0.2 2.0 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KZN84020.1 - 0.0035 17.1 0.0 0.0068 16.2 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair TPR_MLP1_2 PF07926.12 KZN84020.1 - 0.38 10.8 5.1 0.97 9.5 0.4 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein SlyX PF04102.12 KZN84020.1 - 0.43 11.2 2.6 18 6.0 0.1 2.8 2 1 0 2 2 2 0 SlyX DUF4407 PF14362.6 KZN84020.1 - 0.82 9.0 2.8 1.2 8.4 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4201 PF13870.6 KZN84020.1 - 1.8 8.3 8.1 0.65 9.7 3.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Spc7 PF08317.11 KZN84020.1 - 3.6 6.4 8.4 0.44 9.4 2.8 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein SNF2_N PF00176.23 KZN84021.1 - 1.9e-63 214.3 0.0 3.9e-63 213.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KZN84021.1 - 4.6e-19 68.8 0.2 3.7e-17 62.7 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KZN84021.1 - 2e-07 31.2 0.0 5.4e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KZN84021.1 - 0.0053 16.5 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KZN84021.1 - 0.019 14.2 1.2 0.15 11.2 0.0 2.4 3 0 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 Type_III_YscX PF09474.10 KZN84021.1 - 0.023 15.0 0.0 0.071 13.4 0.0 1.8 1 0 0 1 1 1 0 Type III secretion system YscX (type_III_YscX) DSPc PF00782.20 KZN84023.1 - 4.6e-12 45.9 0.1 8.3e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KZN84023.1 - 0.0073 16.6 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain APH PF01636.23 KZN84025.1 - 7.2e-15 55.6 0.0 2e-14 54.1 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN84025.1 - 0.00018 21.2 0.0 0.00051 19.7 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.25 KZN84025.1 - 0.017 14.5 0.0 2.3 7.5 0.0 2.4 2 1 0 2 2 2 0 Protein kinase domain DUF1679 PF07914.11 KZN84025.1 - 0.052 12.4 0.0 0.092 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EamA PF00892.20 KZN84027.1 - 3.2e-05 24.1 1.6 3.2e-05 24.1 1.6 3.8 4 0 0 4 4 4 3 EamA-like transporter family CSG2 PF16965.5 KZN84027.1 - 0.00026 20.1 10.0 0.0024 16.9 7.7 3.0 2 1 0 2 2 2 1 Ceramide synthase regulator Nuc_sug_transp PF04142.15 KZN84027.1 - 0.034 13.3 0.2 0.034 13.3 0.2 2.1 2 0 0 2 2 2 0 Nucleotide-sugar transporter PsbW PF07123.12 KZN84027.1 - 0.1 12.6 1.0 0.23 11.5 0.0 2.1 3 0 0 3 3 3 0 Photosystem II reaction centre W protein (PsbW) DUF973 PF06157.11 KZN84027.1 - 0.59 9.1 5.6 0.16 11.0 2.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF973) TMEM174 PF15029.6 KZN84027.1 - 0.74 9.5 2.7 0.48 10.1 0.3 1.9 1 1 1 2 2 2 0 Transmembrane protein 174 Aldo_ket_red PF00248.21 KZN84028.1 - 6.2e-52 176.6 0.0 7.4e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Tubulin PF00091.25 KZN84030.1 - 6.6e-69 232.1 0.0 1.1e-68 231.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KZN84030.1 - 2.8e-43 147.1 0.3 5.2e-43 146.2 0.0 1.5 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KZN84030.1 - 3.3e-08 33.8 0.0 7e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KZN84030.1 - 0.077 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain zf-AN1 PF01428.16 KZN84031.1 - 8.5e-13 48.2 5.7 8.5e-13 48.2 5.7 1.6 1 1 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 KZN84031.1 - 0.018 15.4 4.2 0.018 15.4 4.2 1.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain DUF1754 PF08555.10 KZN84032.1 - 7.7e-14 52.3 19.3 1.2e-13 51.6 19.3 1.3 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) CDC27 PF09507.10 KZN84032.1 - 0.011 15.1 13.9 0.012 15.0 13.9 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDT1 PF08839.11 KZN84032.1 - 0.091 13.1 2.0 0.11 12.8 2.0 1.1 1 0 0 1 1 1 0 DNA replication factor CDT1 like CAML PF14963.6 KZN84032.1 - 0.65 10.1 7.9 0.74 9.9 7.9 1.0 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Dsh_C PF12316.8 KZN84032.1 - 1.2 9.5 6.3 1.6 9.1 6.3 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF4551 PF15087.6 KZN84032.1 - 3.3 6.5 7.2 3.6 6.3 7.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF908 PF06012.12 KZN84032.1 - 4.4 6.6 5.9 5 6.4 5.9 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) MCM3AP_GANP PF16769.5 KZN84032.1 - 4.6 5.4 9.5 5.5 5.1 9.5 1.0 1 0 0 1 1 1 0 MCM3AP domain of GANP CDC45 PF02724.14 KZN84032.1 - 4.6 5.4 16.7 5.4 5.2 16.7 1.0 1 0 0 1 1 1 0 CDC45-like protein SRP-alpha_N PF04086.13 KZN84032.1 - 5.3 6.9 15.6 6.3 6.6 15.6 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Vfa1 PF08432.10 KZN84032.1 - 6.3 7.1 13.4 7.9 6.8 13.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2201_N PF13203.6 KZN84032.1 - 6.9 6.2 9.7 7.9 6.0 9.7 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain RR_TM4-6 PF06459.12 KZN84032.1 - 8.7 6.1 14.2 10 5.8 14.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Red1 PF07964.11 KZN84032.1 - 9.4 4.3 12.0 10 4.2 12.0 1.0 1 0 0 1 1 1 0 Rec10 / Red1 DUF4457 PF14652.6 KZN84033.1 - 0.0051 16.1 0.0 0.0074 15.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4457) AidB_N PF18158.1 KZN84034.1 - 4.3e-16 59.2 0.0 8.1e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 KZN84034.1 - 1.6e-12 47.9 0.0 3.5e-12 46.8 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KZN84034.1 - 3.5e-10 39.9 0.0 8.3e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain CBM_20 PF00686.19 KZN84035.1 - 4.2e-34 116.3 0.1 1e-33 115.1 0.1 1.7 1 0 0 1 1 1 1 Starch binding domain LPMO_10 PF03067.15 KZN84035.1 - 4.9e-09 37.1 1.3 1.1e-08 36.0 1.3 1.6 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 KZN84035.1 - 0.028 14.4 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 AMPK1_CBM PF16561.5 KZN84035.1 - 0.046 13.9 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase PTPA PF03095.15 KZN84036.1 - 4.1e-108 361.4 0.0 4.8e-108 361.2 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF202 PF02656.15 KZN84037.1 - 3.6e-22 78.6 0.4 3.6e-22 78.6 0.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Macoilin PF09726.9 KZN84037.1 - 0.19 10.2 2.2 0.24 9.9 2.2 1.2 1 0 0 1 1 1 0 Macoilin family RSRP PF17069.5 KZN84037.1 - 2.7 7.5 15.4 4.1 6.9 15.4 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Actin PF00022.19 KZN84038.1 - 1.8e-111 372.7 0.0 1.2e-110 369.9 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KZN84038.1 - 0.0071 15.2 0.0 0.038 12.8 0.0 1.9 1 1 0 1 1 1 1 MreB/Mbl protein NAD_binding_2 PF03446.15 KZN84039.1 - 1.1e-21 77.6 0.1 1.9e-21 76.9 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KZN84039.1 - 3.4e-13 49.9 0.0 6.7e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase IMPDH PF00478.25 KZN84039.1 - 0.021 13.9 0.7 0.72 8.8 0.2 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Shikimate_DH PF01488.20 KZN84039.1 - 0.027 14.5 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF973 PF06157.11 KZN84039.1 - 0.058 12.4 0.0 0.084 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Zemlya PF17646.1 KZN84039.1 - 0.12 12.7 0.3 0.27 11.6 0.1 1.6 2 0 0 2 2 2 0 Closterovirus 1a polyprotein central region DUF3425 PF11905.8 KZN84040.1 - 2.5e-22 79.2 1.6 4.3e-22 78.4 1.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KZN84040.1 - 0.021 14.9 5.8 0.1 12.7 5.8 2.1 1 1 0 1 1 1 0 bZIP transcription factor YabA PF06156.13 KZN84040.1 - 0.22 12.2 0.1 0.45 11.2 0.1 1.4 1 0 0 1 1 1 0 Initiation control protein YabA bZIP_2 PF07716.15 KZN84040.1 - 1.1 9.4 7.2 1.8 8.7 3.9 2.3 1 1 1 2 2 2 0 Basic region leucine zipper GTP_cyclohydro2 PF00925.20 KZN84041.1 - 1.5e-58 197.0 0.0 2.1e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF1325 PF07039.11 KZN84042.1 - 8.1e-35 119.8 0.0 1.5e-34 118.9 0.0 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain LBR_tudor PF09465.10 KZN84042.1 - 0.087 12.6 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Tudor_3 PF18115.1 KZN84042.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain PMI_typeI PF01238.21 KZN84043.1 - 8.5e-148 492.5 0.0 9.9e-148 492.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 KZN84043.1 - 0.0013 18.4 0.3 0.012 15.3 0.2 2.1 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 KZN84043.1 - 0.011 15.7 0.0 3.4 7.6 0.0 2.7 2 0 0 2 2 2 0 AraC-like ligand binding domain NAD_binding_1 PF00175.21 KZN84044.1 - 1.2e-15 58.1 0.0 2.4e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 KZN84044.1 - 5e-08 33.5 0.0 1.3e-07 32.1 0.0 1.7 2 0 0 2 2 2 1 Globin FAD_binding_6 PF00970.24 KZN84044.1 - 1.6e-06 28.4 0.0 2.9e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KZN84044.1 - 2.6e-05 24.4 0.0 0.00047 20.3 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain B PF02216.16 KZN84044.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 B domain TPR_2 PF07719.17 KZN84045.1 - 3.7e-11 42.2 8.7 0.00042 20.2 0.4 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KZN84045.1 - 3e-10 39.5 2.5 0.0013 18.4 0.4 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KZN84045.1 - 9.3e-08 32.3 7.6 0.0008 19.6 0.1 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KZN84045.1 - 1.1e-05 26.0 0.2 0.22 12.2 0.0 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KZN84045.1 - 1.5e-05 24.8 2.1 0.18 12.1 0.1 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KZN84045.1 - 9.8e-05 22.1 0.7 0.097 12.7 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KZN84045.1 - 0.00081 19.2 0.0 0.015 15.1 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KZN84045.1 - 0.0014 19.1 0.0 22 6.0 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KZN84045.1 - 0.0023 18.1 6.0 5.2 7.4 0.1 3.9 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 KZN84045.1 - 0.0034 16.8 0.0 0.13 11.6 0.0 2.5 3 0 0 3 3 3 1 MalT-like TPR region MIT PF04212.18 KZN84045.1 - 0.0051 16.8 1.4 9 6.5 0.1 4.4 4 1 1 5 5 5 1 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 KZN84045.1 - 0.0084 16.8 0.2 19 6.4 0.0 4.5 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KZN84045.1 - 0.012 16.2 0.3 3.5 8.2 0.0 3.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KZN84045.1 - 0.026 14.2 0.1 17 5.2 0.0 3.4 4 0 0 4 4 4 0 TPR repeat Xylo_C PF12529.8 KZN84046.1 - 0.12 12.0 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Xylosyltransferase C terminal adh_short PF00106.25 KZN84048.1 - 1.5e-06 27.8 0.2 1.5e-05 24.6 0.2 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN84048.1 - 0.12 12.3 0.2 0.16 11.8 0.2 1.4 1 1 0 1 1 1 0 KR domain Abhydrolase_3 PF07859.13 KZN84049.1 - 2.2e-23 83.2 0.0 3.2e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KZN84049.1 - 9.6e-21 74.1 0.0 1.3e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KZN84049.1 - 0.0055 16.2 0.0 0.032 13.7 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KZN84049.1 - 0.0086 16.7 1.4 0.013 16.2 1.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 KZN84049.1 - 0.029 13.9 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 KZN84049.1 - 0.029 14.2 0.0 0.15 11.9 0.0 2.1 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Coatomer_E PF04733.14 KZN84050.1 - 2e-59 201.4 4.5 2.3e-59 201.2 4.5 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 KZN84050.1 - 4.7e-10 39.8 16.7 0.0086 16.6 1.2 4.4 2 1 2 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KZN84050.1 - 3.2e-07 30.5 2.4 0.0016 18.6 0.8 3.6 2 1 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KZN84050.1 - 4.1e-07 30.3 13.4 0.01 16.6 0.1 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KZN84050.1 - 1.4e-06 28.9 15.9 0.01 16.4 1.2 3.7 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 KZN84050.1 - 1.2e-05 25.6 5.7 0.0073 16.9 0.4 4.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KZN84050.1 - 0.00041 20.2 13.0 0.038 14.1 0.0 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 KZN84050.1 - 0.00044 20.6 17.4 0.61 10.9 0.1 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 KZN84050.1 - 0.012 15.7 6.3 0.41 10.8 0.1 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KZN84050.1 - 0.015 15.1 4.2 1.3 8.9 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat PYRIN PF02758.16 KZN84050.1 - 0.04 14.1 0.6 4.4 7.5 0.1 2.4 1 1 1 2 2 2 0 PAAD/DAPIN/Pyrin domain TPR_12 PF13424.6 KZN84050.1 - 0.053 13.8 14.0 4.9 7.5 0.1 4.3 3 2 1 4 4 4 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KZN84050.1 - 0.14 12.1 4.2 0.87 9.5 0.4 2.6 1 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal TPR_20 PF14561.6 KZN84050.1 - 1.2 9.6 11.6 0.93 9.9 3.3 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat RVT_1 PF00078.27 KZN84053.1 - 0.0066 16.0 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5082 PF16888.5 KZN84053.1 - 0.0087 16.3 3.4 0.074 13.3 0.2 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF5082) Phage_int_SAM_1 PF02899.17 KZN84053.1 - 0.083 13.2 0.3 0.36 11.2 0.3 2.1 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain MRG PF05712.13 KZN84053.1 - 0.11 11.8 0.2 0.29 10.4 0.2 1.7 1 0 0 1 1 1 0 MRG GreA_GreB_N PF03449.15 KZN84053.1 - 3.3 7.9 4.9 1.1e+02 3.1 0.1 3.4 3 0 0 3 3 3 0 Transcription elongation factor, N-terminal Pox_A_type_inc PF04508.12 KZN84053.1 - 5.4 7.0 4.9 16 5.5 0.4 3.0 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat PI-PLC-X PF00388.19 KZN84054.1 - 2.2e-60 202.4 0.0 4.4e-60 201.5 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KZN84054.1 - 9.1e-44 148.5 0.4 5.3e-43 146.0 0.2 2.4 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_8 PF13833.6 KZN84054.1 - 0.001 18.8 0.1 0.0052 16.6 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_like PF09279.11 KZN84054.1 - 0.0016 18.8 0.2 0.0039 17.6 0.2 1.7 1 1 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like GDPD PF03009.17 KZN84054.1 - 0.02 14.6 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family EF-hand_6 PF13405.6 KZN84054.1 - 0.03 14.2 1.0 0.81 9.8 0.2 2.9 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 KZN84054.1 - 0.097 13.1 0.2 1.2 9.6 0.0 2.6 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 KZN84054.1 - 0.099 12.2 0.8 0.46 10.1 0.1 2.6 3 0 0 3 3 3 0 EF hand p25-alpha PF05517.12 KZN84054.1 - 0.11 12.6 1.4 6.2 7.0 0.5 2.5 1 1 1 2 2 2 0 p25-alpha EF-hand_10 PF14788.6 KZN84054.1 - 0.14 12.0 0.1 9.5 6.2 0.1 2.5 2 0 0 2 2 2 0 EF hand Transp_cyt_pur PF02133.15 KZN84055.1 - 1.2e-150 502.1 42.7 1.4e-150 501.9 42.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF543 PF04418.12 KZN84057.1 - 4.6e-28 97.0 0.1 5.2e-28 96.8 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Urb2 PF10441.9 KZN84058.1 - 1.1e-63 215.0 2.7 1.7e-62 211.0 0.1 2.7 2 0 0 2 2 2 2 Urb2/Npa2 family Elicitin PF00964.17 KZN84058.1 - 0.11 12.6 0.8 0.5 10.5 0.8 2.1 1 0 0 1 1 1 0 Elicitin Metallothio_2 PF01439.18 KZN84059.1 - 0.96 10.4 31.9 0.22 12.4 4.7 4.4 5 0 0 5 5 5 0 Metallothionein GST_N_4 PF17172.4 KZN84060.1 - 2.3e-24 86.0 0.1 3.8e-24 85.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KZN84060.1 - 2e-19 69.1 0.0 4e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KZN84060.1 - 1.1e-13 51.6 0.1 1.8e-13 50.9 0.1 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein SAM35 PF10806.8 KZN84060.1 - 5.3e-07 29.9 0.1 1.5e-06 28.5 0.1 1.7 1 1 1 2 2 2 1 SAM35, subunit of SAM coomplex GST_C_2 PF13410.6 KZN84060.1 - 0.0022 18.0 0.3 0.0041 17.1 0.3 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Methyltransf_25 PF13649.6 KZN84061.1 - 1.6e-07 32.0 0.1 3.6e-07 30.8 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN84061.1 - 2.1e-06 27.6 0.0 4e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN84061.1 - 2.7e-06 27.9 0.1 1.8e-05 25.3 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN84061.1 - 8.1e-06 25.7 0.0 1.3e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN84061.1 - 1.4e-05 25.7 0.0 3e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_33 PF10017.9 KZN84061.1 - 0.00079 18.7 0.0 0.0015 17.7 0.0 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_32 PF13679.6 KZN84061.1 - 0.00084 19.4 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KZN84061.1 - 0.0025 17.2 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.18 KZN84061.1 - 0.037 13.5 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain MTS PF05175.14 KZN84061.1 - 0.085 12.4 0.1 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_7 PF03492.15 KZN84061.1 - 0.21 10.8 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase CDC14 PF08045.11 KZN84062.1 - 2.3e-123 410.8 0.0 2.6e-123 410.7 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component polyprenyl_synt PF00348.17 KZN84063.1 - 1.2e-65 221.1 0.0 1.5e-65 220.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF1771 PF08590.10 KZN84064.1 - 1.2e-25 89.6 5.8 1.2e-25 89.6 5.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 KZN84064.1 - 2.9e-11 43.6 0.3 7.7e-11 42.2 0.3 1.8 1 0 0 1 1 1 1 Smr domain DUF4407 PF14362.6 KZN84064.1 - 0.63 9.3 6.2 0.26 10.6 3.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) G-alpha PF00503.20 KZN84065.1 - 4.3e-124 414.3 2.0 5e-124 414.1 2.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KZN84065.1 - 2.5e-15 56.4 1.7 2.4e-10 40.1 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 KZN84065.1 - 7.4e-05 22.5 0.0 0.00033 20.4 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 KZN84065.1 - 0.0018 17.7 3.4 0.044 13.1 0.1 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KZN84065.1 - 0.0082 16.4 0.9 2.4 8.4 0.0 3.2 2 1 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KZN84065.1 - 0.02 14.6 0.0 0.048 13.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 KZN84065.1 - 0.084 12.4 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MCM PF00493.23 KZN84065.1 - 0.13 11.4 0.1 0.31 10.1 0.1 1.5 1 1 0 1 1 1 0 MCM P-loop domain MMR_HSR1 PF01926.23 KZN84065.1 - 0.14 12.3 0.1 8.9 6.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KZN84065.1 - 0.15 11.4 0.0 0.34 10.2 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Use1 PF09753.9 KZN84066.1 - 1e-08 35.2 5.9 1.7e-08 34.5 5.9 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF4407 PF14362.6 KZN84066.1 - 1.6 8.0 13.6 1.1 8.5 6.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF572 PF04502.13 KZN84066.1 - 2.5 7.6 16.8 3.3 7.3 16.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) BatA PF07584.11 KZN84067.1 - 0.083 13.3 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Rossmann-like PF10727.9 KZN84067.1 - 0.13 12.1 0.0 0.36 10.7 0.0 1.6 1 1 1 2 2 2 0 Rossmann-like domain AMP-binding PF00501.28 KZN84068.1 - 1.4e-91 307.3 0.0 1.7e-91 306.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KZN84068.1 - 1.8e-13 51.2 0.3 4.5e-13 50.0 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Nup188_C PF18378.1 KZN84069.1 - 1.2e-141 471.9 2.1 1.8e-141 471.3 2.1 1.3 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 KZN84069.1 - 3.6e-79 266.8 0.0 1.5e-78 264.7 0.0 1.9 1 1 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 IGPS PF00218.21 KZN84070.1 - 6.7e-97 323.6 0.0 1.5e-96 322.5 0.0 1.6 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 KZN84070.1 - 4.3e-59 199.6 0.0 2e-57 194.1 0.0 2.3 1 1 1 2 2 2 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 KZN84070.1 - 4.1e-47 160.4 0.0 6.9e-47 159.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KZN84070.1 - 4.1e-05 23.4 0.3 0.00012 21.9 0.3 1.7 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 KZN84070.1 - 0.00067 19.5 0.2 0.019 14.7 0.0 2.9 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 KZN84070.1 - 0.012 15.1 0.1 0.052 13.0 0.0 2.0 2 0 0 2 2 2 0 Histidine biosynthesis protein NanE PF04131.14 KZN84070.1 - 0.012 14.8 0.6 0.086 12.0 0.0 2.6 4 0 0 4 4 4 0 Putative N-acetylmannosamine-6-phosphate epimerase IMPDH PF00478.25 KZN84070.1 - 0.035 13.1 0.0 9.7 5.1 0.0 2.8 2 1 0 3 3 3 0 IMP dehydrogenase / GMP reductase domain PTCB-BRCT PF12738.7 KZN84071.1 - 5.3e-06 26.3 0.1 1.7e-05 24.6 0.1 1.9 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KZN84071.1 - 7.7e-06 26.2 0.0 2.4e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KZN84071.1 - 8.1e-05 23.0 0.0 0.00017 22.0 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain WGR PF05406.15 KZN84071.1 - 0.003 17.6 0.1 0.0069 16.4 0.1 1.6 1 0 0 1 1 1 1 WGR domain Peptidase_S74 PF13884.6 KZN84071.1 - 0.12 12.7 0.1 0.24 11.7 0.1 1.5 1 0 0 1 1 1 0 Chaperone of endosialidase Brix PF04427.18 KZN84072.1 - 5.7e-31 108.1 0.0 7.2e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Brix domain UPF1_Zn_bind PF09416.10 KZN84073.1 - 6.1e-72 240.6 2.3 8.3e-72 240.1 1.1 1.9 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 KZN84073.1 - 3.9e-60 202.9 0.0 7.1e-60 202.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KZN84073.1 - 7.9e-54 183.2 2.5 1.8e-30 106.6 0.2 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KZN84073.1 - 1.4e-32 111.8 0.0 2.6e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KZN84073.1 - 1.7e-13 50.7 0.2 1.6e-12 47.5 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KZN84073.1 - 6e-11 42.9 0.1 2.1e-10 41.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KZN84073.1 - 5e-06 26.6 0.0 9.5e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KZN84073.1 - 2e-05 24.4 0.1 0.31 10.7 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KZN84073.1 - 0.00051 19.4 0.1 0.011 14.9 0.0 2.6 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 KZN84073.1 - 0.0006 19.7 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Helicase PIF1 PF05970.14 KZN84073.1 - 0.0029 16.8 0.1 0.56 9.3 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase UvrD-helicase PF00580.21 KZN84073.1 - 0.0035 16.9 0.0 0.041 13.4 0.1 2.5 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain DEAD PF00270.29 KZN84073.1 - 0.012 15.4 0.1 0.021 14.6 0.1 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase ATPase PF06745.13 KZN84073.1 - 0.054 12.8 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_10 PF12846.7 KZN84073.1 - 0.069 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.6 KZN84073.1 - 0.13 12.5 0.0 0.37 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KZN84073.1 - 0.26 11.7 0.5 0.73 10.3 0.5 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4396 PF14342.6 KZN84074.1 - 1.2e-46 158.6 4.3 1.5e-46 158.3 4.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) zf-C2H2_aberr PF17017.5 KZN84075.1 - 1.2e-07 32.0 0.6 2.5e-07 31.0 0.6 1.4 1 0 0 1 1 1 1 Aberrant zinc-finger zf-C2H2 PF00096.26 KZN84075.1 - 0.00017 21.9 19.4 0.35 11.4 3.5 3.8 3 1 0 3 3 3 3 Zinc finger, C2H2 type Cnn_1N PF07989.11 KZN84075.1 - 0.0031 17.6 0.2 0.027 14.6 0.1 2.2 2 0 0 2 2 2 1 Centrosomin N-terminal motif 1 Lebercilin PF15619.6 KZN84075.1 - 0.016 14.9 0.4 0.033 13.9 0.4 1.5 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Trimer_CC PF08954.11 KZN84075.1 - 0.064 12.8 4.2 0.15 11.6 4.2 1.5 1 0 0 1 1 1 0 Trimerisation motif Transpos_assoc PF13963.6 KZN84075.1 - 0.13 12.6 0.4 0.13 12.6 0.4 2.2 1 1 0 2 2 2 0 Transposase-associated domain zf-C2H2_4 PF13894.6 KZN84075.1 - 0.35 11.8 11.2 22 6.2 0.4 3.8 3 1 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KZN84075.1 - 7.1 7.2 15.1 5.5 7.6 0.2 3.6 3 0 0 3 3 3 0 Zinc-finger double domain Methyltransf_34 PF11312.8 KZN84077.1 - 1.5e-101 339.7 0.0 2e-101 339.3 0.0 1.1 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase DUF3395 PF11875.8 KZN84077.1 - 0.5 10.3 2.8 1.1 9.2 2.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3395) Band_7 PF01145.25 KZN84078.1 - 1.3e-24 87.2 8.6 3e-24 86.0 8.6 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 KZN84078.1 - 0.0013 17.9 3.5 0.0017 17.5 3.5 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial PknG_rubred PF16919.5 KZN84078.1 - 0.066 13.4 0.2 0.11 12.6 0.2 1.3 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain UcrQ PF02939.16 KZN84079.1 - 1.1e-31 108.6 0.1 1.3e-31 108.4 0.1 1.1 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 KZN84079.1 - 0.016 15.5 0.0 0.024 15.1 0.0 1.2 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 Spermine_synth PF01564.17 KZN84080.1 - 7.1e-73 244.0 0.0 9.9e-73 243.6 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KZN84080.1 - 1.5e-23 82.4 0.1 2.5e-23 81.7 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 KZN84080.1 - 2.3e-05 25.0 0.0 6e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN84080.1 - 0.00021 22.0 0.2 0.0021 18.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KZN84080.1 - 0.049 13.2 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 KZN84080.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.18 KZN84081.1 - 3.4e-15 55.8 0.2 6.4e-15 54.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN84081.1 - 3e-11 43.2 7.3 5.8e-11 42.3 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0731 PF14982.6 KZN84081.1 - 0.059 13.6 1.5 0.16 12.2 1.5 1.7 1 0 0 1 1 1 0 UPF0731 family 3HCDH_N PF02737.18 KZN84084.1 - 3.4e-24 85.7 0.0 5.3e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KZN84084.1 - 6.1e-11 42.8 0.1 2.1e-10 41.1 0.0 1.9 1 1 1 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KZN84084.1 - 0.041 14.0 0.0 0.084 13.0 0.0 1.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Transketolase_N PF00456.21 KZN84085.1 - 1.8e-78 263.9 0.2 2.4e-78 263.4 0.2 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KZN84085.1 - 2.3e-45 154.5 0.0 4.1e-45 153.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KZN84085.1 - 3.8e-11 43.0 0.0 9.6e-11 41.6 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 KZN84085.1 - 0.046 12.7 0.0 0.1 11.5 0.0 1.5 2 0 0 2 2 2 0 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KZN84085.1 - 0.074 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase FAD_binding_3 PF01494.19 KZN84086.1 - 1.4e-80 271.2 0.0 9.8e-57 192.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Phe_hydrox_dim PF07976.12 KZN84086.1 - 4.7e-36 124.3 0.0 8.4e-36 123.5 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 KZN84086.1 - 7e-05 21.7 0.0 0.00011 21.1 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KZN84086.1 - 0.00011 21.5 0.0 0.00018 20.8 0.0 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KZN84086.1 - 0.00019 21.6 0.1 0.00057 20.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KZN84086.1 - 0.00026 20.3 0.0 0.0023 17.2 0.0 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KZN84086.1 - 0.0034 16.5 0.0 0.0057 15.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KZN84086.1 - 0.0042 16.7 0.2 0.016 14.8 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KZN84086.1 - 0.0059 16.0 0.0 0.0087 15.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KZN84086.1 - 0.011 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 KZN84086.1 - 0.014 15.9 0.0 0.032 14.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KZN84086.1 - 0.062 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KZN84086.1 - 0.13 11.6 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sugar_tr PF00083.24 KZN84087.1 - 9.2e-137 456.6 22.8 1.1e-136 456.4 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN84087.1 - 3.2e-32 111.8 50.9 2.3e-25 89.3 25.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KZN84087.1 - 3.8e-06 25.7 24.1 4.4e-05 22.2 5.7 2.8 2 2 1 3 3 3 2 MFS/sugar transport protein Pox_A14 PF05767.12 KZN84087.1 - 1.2 9.3 4.6 8.3 6.6 0.0 3.6 3 1 0 3 3 3 0 Poxvirus virion envelope protein A14 DUF3533 PF12051.8 KZN84088.1 - 3.1e-87 293.0 14.3 3.7e-87 292.7 14.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Nse5 PF08691.10 KZN84088.1 - 0.16 10.6 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 Fungal_trans PF04082.18 KZN84089.1 - 5.2e-35 120.8 0.0 1e-34 119.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN84089.1 - 1e-08 35.2 14.7 1.7e-08 34.4 14.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.21 KZN84089.1 - 0.06 13.4 0.2 0.18 11.9 0.2 1.8 1 0 0 1 1 1 0 bZIP transcription factor DUF5365 PF17326.2 KZN84089.1 - 0.13 12.7 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5365) DUF4635 PF15466.6 KZN84089.1 - 0.18 11.3 0.3 0.49 9.9 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) SET PF00856.28 KZN84090.1 - 0.00034 21.0 0.0 0.00061 20.2 0.0 1.5 1 0 0 1 1 1 1 SET domain PhaP_Bmeg PF09602.10 KZN84090.1 - 0.09 12.7 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) MMR_HSR1_C PF08438.10 KZN84092.1 - 2.2e-36 124.8 0.0 3.8e-36 124.1 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 KZN84092.1 - 7e-08 32.5 0.0 1.7e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AMP-binding PF00501.28 KZN84094.1 - 1.1e-64 218.6 0.0 1.7e-64 218.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KZN84094.1 - 4.5e-33 114.5 0.0 5.9e-23 81.3 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein AMP-binding_C PF13193.6 KZN84094.1 - 3.6e-11 43.9 0.0 1.3e-10 42.1 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 KZN84094.1 - 2.5e-09 37.4 0.2 5.7e-09 36.2 0.2 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KZN84094.1 - 5e-07 29.4 0.0 0.0034 16.9 0.0 2.6 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KZN84094.1 - 0.0002 20.5 0.0 0.069 12.1 0.0 2.9 2 1 1 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KZN84094.1 - 0.00037 20.9 0.0 0.0012 19.3 0.0 1.9 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 KZN84094.1 - 0.085 12.8 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 KR domain Aminotran_1_2 PF00155.21 KZN84095.1 - 2.9e-33 115.5 0.0 3.7e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 KZN84095.1 - 0.001 17.9 0.0 0.17 10.6 0.0 2.2 2 0 0 2 2 2 2 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.20 KZN84095.1 - 0.042 12.4 0.0 0.083 11.4 0.0 1.5 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme DUF3834 PF12916.7 KZN84095.1 - 0.055 12.7 0.0 10 5.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3834) Ribosomal_L7Ae PF01248.26 KZN84098.1 - 8.7e-19 67.1 1.6 8.7e-19 67.1 1.6 2.5 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Topoisom_I_N PF02919.15 KZN84098.1 - 6.3 6.2 8.6 13 5.2 8.6 1.4 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment MAD PF05557.13 KZN84099.1 - 8.8e-59 199.5 73.2 4.6e-50 170.7 74.5 2.0 2 0 0 2 2 2 2 Mitotic checkpoint protein Flp_N PF03930.14 KZN84099.1 - 0.044 13.8 0.8 0.21 11.6 0.5 2.4 1 1 0 1 1 1 0 Recombinase Flp protein N-terminus DUF5320 PF17253.2 KZN84099.1 - 0.19 12.8 0.1 0.19 12.8 0.1 7.8 6 4 2 8 8 8 0 Family of unknown function (DUF5320) GPHR_N PF12537.8 KZN84099.1 - 0.67 10.1 5.6 3 8.0 0.6 3.8 3 0 0 3 3 3 0 The Golgi pH Regulator (GPHR) Family N-terminal muHD PF10291.9 KZN84100.1 - 7.9e-84 281.2 0.0 1.1e-83 280.7 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 KZN84100.1 - 1e-07 32.1 0.1 5.3e-07 29.8 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain GARP PF16731.5 KZN84100.1 - 0.018 14.7 5.1 0.049 13.3 5.1 1.8 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma COG2 PF06148.11 KZN84100.1 - 0.023 14.8 1.5 0.11 12.6 0.5 2.6 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1202 PF06717.11 KZN84100.1 - 0.1 12.0 0.3 0.2 11.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) Pkinase PF00069.25 KZN84101.1 - 1.2e-46 159.2 0.0 1.6e-46 158.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN84101.1 - 9.9e-17 61.1 0.0 1.5e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KZN84101.1 - 3e-07 30.6 0.7 0.0023 17.9 0.5 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KZN84101.1 - 0.00015 20.7 0.0 0.0003 19.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KZN84101.1 - 0.00087 18.7 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KZN84101.1 - 0.003 17.0 0.0 0.0083 15.5 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family KIX_2 PF16987.5 KZN84101.1 - 0.0034 17.4 0.2 0.0055 16.7 0.2 1.3 1 0 0 1 1 1 1 KIX domain YrbL-PhoP_reg PF10707.9 KZN84101.1 - 0.15 11.6 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 KZN84101.1 - 0.17 11.5 0.0 0.35 10.5 0.0 1.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SH3_9 PF14604.6 KZN84102.1 - 4.3e-08 32.9 0.0 9.6e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KZN84102.1 - 9.2e-06 25.2 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KZN84102.1 - 0.00048 19.8 0.0 0.00099 18.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain RIFIN PF02009.16 KZN84102.1 - 0.0026 17.7 0.5 0.0056 16.6 0.5 1.4 1 0 0 1 1 1 1 Rifin DUF347 PF03988.12 KZN84102.1 - 0.027 14.7 2.5 0.073 13.3 2.5 1.8 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Syndecan PF01034.20 KZN84102.1 - 0.038 13.9 0.1 0.086 12.8 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain Macoilin PF09726.9 KZN84102.1 - 0.69 8.4 7.4 1.1 7.7 7.4 1.2 1 0 0 1 1 1 0 Macoilin family CPSF100_C PF13299.6 KZN84102.1 - 1.5 9.0 5.4 3 8.0 5.4 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Plasmodium_Vir PF05795.11 KZN84102.1 - 1.9 7.9 4.6 3.1 7.1 4.6 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Presenilin PF01080.17 KZN84102.1 - 2.2 7.0 4.3 3.5 6.3 4.3 1.3 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 KZN84102.1 - 2.4 7.9 12.7 3.2 7.5 12.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 LapA_dom PF06305.11 KZN84102.1 - 5.2 7.0 4.4 0.99 9.3 0.4 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Tim54 PF11711.8 KZN84102.1 - 9.8 4.8 9.1 15 4.3 9.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Ank_2 PF12796.7 KZN84104.1 - 1.2e-22 80.3 0.0 2.8e-13 50.2 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN84104.1 - 1.4e-15 57.5 0.1 9.1e-08 32.5 0.0 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KZN84104.1 - 2.8e-15 56.0 0.0 3.6e-05 24.0 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KZN84104.1 - 9.2e-13 48.2 1.1 7e-08 32.6 0.0 3.8 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN84104.1 - 1.9e-12 46.2 0.2 0.0031 17.9 0.0 4.6 4 1 0 4 4 4 4 Ankyrin repeat YmzC PF14157.6 KZN84104.1 - 0.16 12.1 0.0 6.6 6.9 0.0 2.3 2 0 0 2 2 2 0 YmzC-like protein LtuB PF17455.2 KZN84104.1 - 0.21 12.2 0.4 4.5 7.9 0.0 2.3 1 1 1 2 2 2 0 Late transcription unit B Sugar_tr PF00083.24 KZN84105.1 - 7.3e-109 364.6 15.3 9.1e-109 364.3 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN84105.1 - 1.4e-17 63.7 27.4 1.5e-14 53.7 3.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KZN84105.1 - 1.1e-06 27.3 2.5 1.1e-06 27.3 2.5 1.7 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family PRCC PF10253.9 KZN84107.1 - 0.79 10.5 11.0 1.1 10.0 11.0 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting MFS_1 PF07690.16 KZN84108.1 - 3.6e-38 131.4 28.9 3.6e-38 131.4 28.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN84108.1 - 4.9e-13 48.7 5.5 4.9e-13 48.7 5.5 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter DUF1453 PF07301.11 KZN84108.1 - 1.2 9.1 5.6 0.47 10.5 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1453) OPT PF03169.15 KZN84109.1 - 3.1e-175 584.3 11.2 3.6e-175 584.2 11.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein RXT2_N PF08595.11 KZN84109.1 - 2.3 8.2 4.4 0.95 9.5 0.1 2.3 3 0 0 3 3 3 0 RXT2-like, N-terminal ERG4_ERG24 PF01222.17 KZN84110.1 - 3.8e-135 451.0 21.4 4.7e-135 450.7 21.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Acetyltransf_1 PF00583.25 KZN84111.1 - 0.00021 21.5 0.1 0.00047 20.4 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 KZN84111.1 - 0.0047 17.0 0.0 0.019 15.1 0.0 1.9 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.7 KZN84111.1 - 0.0097 16.3 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KZN84111.1 - 0.046 13.7 0.0 0.12 12.3 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KZN84111.1 - 0.16 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein TPP_enzyme_N PF02776.18 KZN84112.1 - 1.8e-21 76.5 0.2 4.3e-21 75.3 0.2 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KZN84112.1 - 1.1e-11 44.6 0.0 5.1e-11 42.4 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain ArsD PF06953.11 KZN84112.1 - 0.061 13.7 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Arsenical resistance operon trans-acting repressor ArsD 4HBT_2 PF13279.6 KZN84113.1 - 4.1e-08 33.7 0.0 6.5e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily JmjC PF02373.22 KZN84114.1 - 2.1e-38 131.2 1.9 3.4e-38 130.6 0.6 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 KZN84114.1 - 2.6e-17 62.9 3.8 4.6e-17 62.2 3.8 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KZN84114.1 - 5.4e-17 61.8 3.9 1.2e-16 60.7 3.9 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.17 KZN84114.1 - 3.5e-15 55.7 0.3 8.9e-15 54.4 0.3 1.8 1 0 0 1 1 1 1 jmjN domain AA_permease_2 PF13520.6 KZN84115.1 - 1.1e-60 205.6 52.6 1.4e-60 205.3 52.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN84115.1 - 9.6e-33 113.5 48.1 1.3e-32 113.1 48.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3493 PF11998.8 KZN84115.1 - 0.21 11.7 2.0 0.67 10.2 0.0 2.9 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 ACBP PF00887.19 KZN84116.1 - 3.2e-21 75.3 0.1 1.3e-20 73.4 0.0 2.1 2 1 0 2 2 2 1 Acyl CoA binding protein APAF1_C PF17908.1 KZN84116.1 - 0.1 12.6 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 APAF-1 helical domain Zip PF02535.22 KZN84116.1 - 7.3 5.7 5.1 9.9 5.3 5.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Glyco_hydro_71 PF03659.14 KZN84117.1 - 7.2e-136 452.9 2.2 9.7e-136 452.5 2.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 CHCH PF06747.13 KZN84118.1 - 8.3e-07 29.0 6.6 8.3e-07 29.0 6.6 2.6 3 0 0 3 3 3 2 CHCH domain CX9C PF16860.5 KZN84118.1 - 0.0018 18.2 9.5 0.003 17.6 3.5 2.3 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 KZN84118.1 - 0.12 12.7 10.9 1.7 9.0 3.2 3.0 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 KZN84118.1 - 3.7 7.6 14.5 3.2 7.9 4.7 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.17 KZN84118.1 - 4.8 7.5 11.4 6.4 7.1 0.8 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Nup54 PF13874.6 KZN84119.1 - 5e-42 143.3 1.5 2.6e-41 141.0 0.0 2.3 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 KZN84119.1 - 7.6e-13 47.8 2.3 1.4e-12 46.9 2.3 1.5 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain Nucleoporin_FG PF13634.6 KZN84119.1 - 4.7e-09 37.0 67.2 3.9e-06 27.6 36.9 3.3 1 1 1 2 2 2 2 Nucleoporin FG repeat region Fib_alpha PF08702.10 KZN84119.1 - 2.5e-05 24.5 2.1 5e-05 23.5 2.1 1.5 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family DUF745 PF05335.13 KZN84119.1 - 0.013 15.3 4.7 0.013 15.3 4.7 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF745) DUF3867 PF12983.7 KZN84119.1 - 0.028 14.5 3.3 0.035 14.1 2.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3867) Adhesin_P1_N PF18652.1 KZN84119.1 - 0.059 13.4 3.4 0.2 11.7 3.4 1.9 1 1 0 1 1 1 0 Adhesin P1 N-terminal domain V-SNARE_C PF12352.8 KZN84119.1 - 0.07 13.4 1.9 6.7 7.1 0.1 2.6 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus DUF948 PF06103.11 KZN84119.1 - 0.071 13.4 0.2 2.3 8.5 0.1 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) EzrA PF06160.12 KZN84119.1 - 0.087 11.0 6.9 0.075 11.2 4.2 1.8 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Spc24 PF08286.11 KZN84119.1 - 0.18 12.0 4.3 0.8 10.0 0.8 2.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF5082 PF16888.5 KZN84119.1 - 0.3 11.4 6.9 0.16 12.3 3.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) GAS PF13851.6 KZN84119.1 - 0.62 9.4 9.4 0.6 9.4 7.1 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4164 PF13747.6 KZN84119.1 - 0.86 9.9 5.1 1.2 9.4 3.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Spc7 PF08317.11 KZN84119.1 - 0.93 8.3 10.0 1.1 8.1 9.0 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein Spectrin PF00435.21 KZN84119.1 - 0.93 10.0 6.5 4 8.0 5.7 2.4 1 1 1 2 2 2 0 Spectrin repeat DUF1664 PF07889.12 KZN84119.1 - 1.5 8.8 4.0 4.1 7.5 2.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Tup_N PF08581.10 KZN84119.1 - 2.1 8.7 6.5 0.64 10.4 1.7 2.5 3 0 0 3 3 3 0 Tup N-terminal ABC_tran_CTD PF16326.5 KZN84119.1 - 5 7.4 6.8 8.5 6.7 2.6 2.6 1 1 1 2 2 2 0 ABC transporter C-terminal domain Snapin_Pallidin PF14712.6 KZN84119.1 - 6.2 7.3 8.7 23 5.5 2.2 3.1 1 1 3 4 4 4 0 Snapin/Pallidin Prefoldin PF02996.17 KZN84119.1 - 9.6 6.2 7.8 5.8 6.9 1.2 2.8 1 1 0 2 2 2 0 Prefoldin subunit Tom5 PF10642.9 KZN84120.1 - 5.8e-21 74.3 0.3 6.3e-21 74.1 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Med26 PF08711.11 KZN84121.1 - 1.7e-11 44.0 0.3 3.2e-11 43.1 0.3 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain HIG_1_N PF04588.13 KZN84122.1 - 2.5e-07 30.8 1.3 2.5e-07 30.8 1.3 1.7 2 0 0 2 2 2 1 Hypoxia induced protein conserved region DUF4741 PF15897.5 KZN84122.1 - 0.11 12.3 3.7 0.19 11.5 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4741) DASH_Ask1 PF08655.10 KZN84123.1 - 1.1e-29 102.1 0.4 2.1e-29 101.2 0.3 1.6 2 0 0 2 2 2 1 DASH complex subunit Ask1 Pkinase PF00069.25 KZN84125.1 - 1.2e-51 175.6 0.0 1.6e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN84125.1 - 5.5e-22 78.3 0.0 7.5e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KZN84125.1 - 0.00047 19.2 0.0 0.00059 18.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KZN84125.1 - 0.0016 17.8 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KZN84125.1 - 0.01 15.4 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KZN84125.1 - 0.011 15.1 0.1 0.019 14.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KZN84125.1 - 0.029 14.3 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4167 PF13763.6 KZN84125.1 - 0.031 14.4 0.0 0.061 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4167) FTA2 PF13095.6 KZN84125.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF1944 PF09175.10 KZN84125.1 - 0.17 11.7 0.1 1.4 8.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1944) Thiolase_N PF00108.23 KZN84128.1 - 4.8e-68 229.3 0.1 7.1e-68 228.8 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KZN84128.1 - 4.2e-41 139.4 1.6 5.4e-41 139.1 0.3 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KZN84128.1 - 0.0032 17.1 2.3 0.0065 16.1 1.6 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain WLM PF08325.10 KZN84129.1 - 1.2e-51 175.6 0.1 3.4e-51 174.0 0.0 1.7 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.17 KZN84129.1 - 0.004 17.2 0.1 0.01 15.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function DUF45 SprT-like PF10263.9 KZN84129.1 - 0.0057 16.5 0.1 0.02 14.7 0.1 1.6 1 1 0 1 1 1 1 SprT-like family Zn_clus PF00172.18 KZN84130.1 - 3.9e-10 39.7 10.7 7e-10 38.9 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KZN84131.1 - 4.9e-117 391.5 20.9 5.6e-117 391.4 20.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN84131.1 - 1.8e-27 96.2 26.9 3.1e-20 72.4 3.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Cation_ATPase_C PF00689.21 KZN84132.1 - 3.5e-43 147.4 9.7 3.5e-43 147.4 9.7 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KZN84132.1 - 3.9e-37 127.5 0.4 3.9e-37 127.5 0.4 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KZN84132.1 - 1.9e-19 70.8 0.1 5e-19 69.4 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KZN84132.1 - 1.7e-17 63.3 0.0 3.1e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KZN84132.1 - 1.7e-08 34.0 0.1 9.5e-08 31.6 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KZN84132.1 - 0.00064 19.5 0.2 0.0024 17.7 0.3 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase IBR PF01485.21 KZN84133.1 - 3e-12 46.6 44.5 6.9e-06 26.2 14.3 4.5 4 0 0 4 4 4 4 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KZN84133.1 - 0.0013 18.6 3.4 0.0013 18.6 3.4 4.5 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KZN84133.1 - 0.011 15.6 3.8 0.011 15.6 3.8 5.0 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) ERG2_Sigma1R PF04622.12 KZN84133.1 - 0.2 10.9 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 ERG2 and Sigma1 receptor like protein HSP70 PF00012.20 KZN84134.1 - 3.3e-161 537.5 2.3 3.3e-161 537.5 2.3 1.9 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KZN84134.1 - 5.4e-11 41.9 0.0 5.4e-10 38.6 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KZN84134.1 - 0.0027 18.1 0.5 2.4 8.6 0.0 3.0 2 1 0 2 2 2 2 Cell division protein FtsA DUF2746 PF10874.8 KZN84134.1 - 0.13 12.7 0.0 0.57 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) Chitin_synth_2 PF03142.15 KZN84135.1 - 5.3e-26 91.3 2.0 4.8e-24 84.9 1.3 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KZN84135.1 - 2.2e-14 53.8 4.1 2.2e-14 53.8 4.1 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KZN84135.1 - 2.5e-09 37.4 0.0 5.9e-09 36.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 La PF05383.17 KZN84136.1 - 1.5e-21 76.2 0.0 2.5e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KZN84136.1 - 1.1e-08 34.8 0.1 2.6e-08 33.6 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tmp39 PF10271.9 KZN84136.1 - 0.34 9.9 0.0 0.47 9.4 0.0 1.1 1 0 0 1 1 1 0 Putative transmembrane protein Dabb PF07876.12 KZN84137.1 - 5.3e-18 65.4 0.0 5.9e-18 65.3 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain AAA_12 PF13087.6 KZN84138.1 - 6.3e-38 130.4 0.0 1.3e-37 129.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KZN84138.1 - 1.4e-28 100.4 0.0 2.7e-28 99.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KZN84138.1 - 5.3e-09 36.6 0.0 2e-08 34.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KZN84138.1 - 1.6e-08 34.5 0.0 0.0031 17.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KZN84138.1 - 0.00025 20.8 0.1 0.32 10.7 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 KZN84138.1 - 0.00048 19.7 0.0 0.084 12.3 0.0 2.8 3 0 0 3 3 3 1 PhoH-like protein AAA_18 PF13238.6 KZN84138.1 - 0.00062 20.3 0.0 0.0021 18.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KZN84138.1 - 0.0015 18.1 0.0 0.0032 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KZN84138.1 - 0.0057 16.5 0.0 0.025 14.4 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA PF00004.29 KZN84138.1 - 0.016 15.7 0.0 0.046 14.2 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KZN84138.1 - 0.023 13.9 0.1 0.23 10.7 0.0 2.6 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 KZN84138.1 - 0.029 14.8 0.0 0.066 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KZN84138.1 - 0.074 13.1 0.0 0.4 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sulfatase PF00884.23 KZN84139.1 - 3.4e-21 75.9 0.6 6.7e-21 75.0 0.6 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KZN84139.1 - 0.00028 20.6 0.0 0.00049 19.8 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KZN84139.1 - 0.09 11.4 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF4059 PF13268.6 KZN84139.1 - 0.094 13.1 2.0 0.64 10.5 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4059) APH PF01636.23 KZN84140.1 - 1e-12 48.5 0.0 5.3e-12 46.2 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN84140.1 - 0.017 14.7 0.7 0.078 12.5 0.1 2.2 3 0 0 3 3 3 0 Choline/ethanolamine kinase SUI1 PF01253.22 KZN84141.1 - 7.7e-22 77.6 0.9 1.8e-21 76.4 0.4 2.0 2 0 0 2 2 2 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 KZN84141.1 - 3.9e-09 37.1 2.1 2.3e-08 34.6 0.2 2.9 2 1 0 2 2 2 1 Pre-PUA-like domain Kin17_mid PF10357.9 KZN84141.1 - 0.04 13.8 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein LHH PF14411.6 KZN84143.1 - 0.12 12.5 0.1 0.35 11.1 0.0 1.8 2 0 0 2 2 2 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH Glyco_hydro_61 PF03443.14 KZN84144.1 - 1.4e-67 227.6 1.1 5.5e-67 225.7 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 TIG PF01833.24 KZN84145.1 - 2.8e-10 40.1 0.4 8.9e-10 38.5 0.2 2.0 2 0 0 2 2 2 1 IPT/TIG domain Ank_5 PF13857.6 KZN84145.1 - 6.9e-09 35.8 4.1 2.3e-05 24.6 1.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KZN84145.1 - 1e-06 28.9 2.8 0.018 15.4 0.8 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KZN84145.1 - 2.8e-06 27.8 0.0 6.1e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN84145.1 - 5e-05 23.8 0.6 0.00028 21.4 0.3 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN84145.1 - 0.0005 20.3 0.4 2.2 9.1 0.2 2.8 2 0 0 2 2 2 2 Ankyrin repeat Aminotran_3 PF00202.21 KZN84146.1 - 5.8e-52 176.7 0.0 6.8e-51 173.2 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-III MBOAT_2 PF13813.6 KZN84147.1 - 6e-25 87.3 0.0 1.8e-24 85.8 0.0 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family TRAPPC10 PF12584.8 KZN84148.1 - 2.2e-46 157.4 0.0 4.4e-46 156.4 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.8 KZN84148.1 - 0.02 14.5 0.5 0.039 13.5 0.5 1.4 1 0 0 1 1 1 0 Foie gras liver health family 1 UBN_AB PF14075.6 KZN84148.1 - 0.063 13.0 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Ubinuclein conserved middle domain FA_desaturase PF00487.24 KZN84149.1 - 3.5e-23 82.7 17.9 8e-23 81.6 17.9 1.6 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KZN84149.1 - 2e-05 24.8 0.0 4.7e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Rad51 PF08423.11 KZN84150.1 - 1.9e-43 148.6 0.0 6e-40 137.1 0.0 2.1 2 0 0 2 2 2 2 Rad51 AAA_25 PF13481.6 KZN84150.1 - 3.8e-12 46.2 0.0 6.6e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KZN84150.1 - 2.6e-07 30.2 0.3 1.4e-06 27.8 0.3 2.0 1 1 0 1 1 1 1 KaiC RecA PF00154.21 KZN84150.1 - 7.3e-07 28.9 0.0 4.4e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_24 PF13479.6 KZN84150.1 - 0.00099 18.9 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 KZN84150.1 - 0.002 17.5 0.3 0.025 13.9 0.3 2.1 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain NACHT PF05729.12 KZN84150.1 - 0.002 18.1 0.0 0.0039 17.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KZN84150.1 - 0.065 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 KZN84150.1 - 0.13 11.7 0.1 0.23 10.9 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_16 PF13191.6 KZN84150.1 - 0.14 12.5 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Phage_1_1 PF08200.11 KZN84151.1 - 0.038 14.4 0.7 0.7 10.4 0.1 2.2 2 0 0 2 2 2 0 Bacteriophage 1.1 Protein Velvet PF11754.8 KZN84152.1 - 1e-52 179.6 1.8 8.8e-31 107.7 0.0 3.0 2 1 1 3 3 3 2 Velvet factor Med9 PF07544.13 KZN84153.1 - 0.064 13.3 0.8 0.19 11.9 0.8 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 MFS_1 PF07690.16 KZN84154.1 - 5.5e-18 65.0 49.8 7.9e-12 44.8 23.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyclase PF04199.13 KZN84155.1 - 5.8e-12 46.0 0.0 9.8e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Putative cyclase Luteo_Vpg PF01659.16 KZN84155.1 - 0.42 11.0 2.1 0.8 10.1 2.1 1.4 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein LSM14 PF12701.7 KZN84156.1 - 1.4e-27 95.5 0.0 2.4e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 KZN84156.1 - 4.6e-20 72.4 1.9 1e-19 71.3 1.9 1.6 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.6 KZN84156.1 - 4.2e-06 26.8 0.0 7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.22 KZN84156.1 - 0.26 11.0 0.0 0.4 10.4 0.0 1.3 1 0 0 1 1 1 0 LSM domain WD40 PF00400.32 KZN84157.1 - 5e-21 74.6 6.2 0.00027 21.7 0.1 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN84157.1 - 1.7e-05 25.1 0.1 0.48 10.7 0.0 3.9 3 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Reg_prop PF07494.11 KZN84157.1 - 0.0062 16.6 0.0 0.62 10.5 0.0 2.9 2 0 0 2 2 2 1 Two component regulator propeller BRK PF07533.16 KZN84157.1 - 0.0084 15.7 0.0 39 4.0 0.0 3.8 3 0 0 3 3 3 0 BRK domain Nup160 PF11715.8 KZN84157.1 - 0.027 13.1 0.2 0.34 9.5 0.2 2.5 3 0 0 3 3 3 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KZN84157.1 - 0.039 14.4 1.3 11 6.7 0.0 4.2 4 1 1 5 5 5 0 PQQ-like domain Sigma70_r1_2 PF00140.20 KZN84157.1 - 0.047 13.7 1.0 0.14 12.2 1.0 1.9 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 Thioredox_DsbH PF03190.15 KZN84158.1 - 2.2e-71 239.1 0.1 3.7e-71 238.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 KZN84158.1 - 6.4e-07 29.5 0.0 1.3e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_9 PF00759.19 KZN84158.1 - 0.0075 15.7 0.1 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 C5-epim_C PF06662.13 KZN84158.1 - 0.054 13.0 0.6 8 5.9 0.0 2.8 3 0 0 3 3 3 0 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_47 PF01532.20 KZN84158.1 - 0.19 10.6 0.0 0.32 9.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 47 CAP PF00188.26 KZN84159.1 - 5.3e-17 62.8 1.6 5.3e-17 62.8 1.6 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family DUF5435 PF17503.2 KZN84159.1 - 1.6 8.4 6.2 0.17 11.6 1.8 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5435) Carn_acyltransf PF00755.20 KZN84160.1 - 1.9e-208 693.9 0.0 4.3e-208 692.7 0.0 1.5 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase Ligase_CoA PF00549.19 KZN84160.1 - 9.6e-35 119.7 0.3 2.9e-16 59.6 0.2 2.5 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.19 KZN84160.1 - 8.1e-18 64.9 0.1 2e-17 63.7 0.1 1.7 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.6 KZN84160.1 - 9.2e-10 38.5 0.0 6.2e-09 35.8 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KZN84160.1 - 0.0046 17.5 0.1 0.014 15.9 0.1 1.9 1 0 0 1 1 1 1 CoA binding domain RTA1 PF04479.13 KZN84161.1 - 1.8e-62 210.6 4.1 2.3e-62 210.3 4.1 1.1 1 0 0 1 1 1 1 RTA1 like protein DAG1 PF05454.11 KZN84161.1 - 0.22 10.8 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) RicinB_lectin_2 PF14200.6 KZN84162.1 - 4.9e-05 24.0 0.0 0.019 15.7 0.0 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Inhibitor_I66 PF16850.5 KZN84162.1 - 0.018 14.9 0.0 0.39 10.6 0.0 2.1 1 1 1 2 2 2 0 Peptidase inhibitor I66 Jak1_Phl PF17887.1 KZN84163.1 - 0.04 13.9 2.1 0.063 13.2 2.1 1.3 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain PRCC PF10253.9 KZN84163.1 - 1.6 9.5 11.9 2.1 9.1 11.9 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Pannexin_like PF12534.8 KZN84163.1 - 6.6 5.7 5.7 4.9 6.1 3.5 1.7 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 Rad60-SLD PF11976.8 KZN84164.1 - 3.1e-20 71.8 0.2 3.6e-20 71.6 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KZN84164.1 - 1e-10 41.2 0.1 1.2e-10 41.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Nup84_Nup100 PF04121.13 KZN84165.1 - 2.9e-175 584.4 0.0 4.3e-175 583.9 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 LpqV PF17301.2 KZN84165.1 - 0.031 14.5 0.0 0.084 13.1 0.0 1.7 1 0 0 1 1 1 0 Putative lipoprotein LpqV HypD PF01924.16 KZN84165.1 - 0.19 10.8 0.1 0.32 10.0 0.1 1.3 1 0 0 1 1 1 0 Hydrogenase formation hypA family CDC45 PF02724.14 KZN84165.1 - 5.8 5.1 13.3 10 4.3 13.3 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF2203 PF09969.9 KZN84165.1 - 9.2 7.0 6.6 1.1 10.0 0.3 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Cation_ATPase_C PF00689.21 KZN84166.1 - 1.2e-45 155.5 7.5 1.2e-45 155.5 7.5 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KZN84166.1 - 2e-39 135.0 0.4 2e-39 135.0 0.4 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KZN84166.1 - 3.7e-21 75.0 0.0 7.1e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KZN84166.1 - 2.3e-19 70.5 0.1 1.1e-18 68.3 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KZN84166.1 - 6.6e-09 35.3 0.2 2.5e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KZN84166.1 - 5.4e-05 23.1 1.8 0.00029 20.7 1.7 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 KZN84166.1 - 0.17 10.7 3.6 0.4 9.5 3.6 1.6 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG APH PF01636.23 KZN84167.1 - 2e-11 44.3 0.0 3.2e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN84167.1 - 0.0023 17.5 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase PepSY_2 PF13670.6 KZN84168.1 - 0.097 12.7 0.2 1.7 8.7 0.0 2.7 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain MANEC PF07502.14 KZN84169.1 - 0.00025 21.2 2.8 0.35 11.2 0.7 2.5 2 0 0 2 2 2 2 MANEC domain PAN_4 PF14295.6 KZN84169.1 - 0.012 15.5 17.3 0.13 12.2 0.9 3.0 3 0 0 3 3 3 0 PAN domain D-ser_dehydrat PF14031.6 KZN84170.1 - 1.4e-22 80.1 0.2 3.5e-22 78.9 0.2 1.7 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KZN84170.1 - 3e-12 46.7 0.0 4.3e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain adh_short PF00106.25 KZN84171.1 - 1.1e-44 152.2 0.2 1.5e-44 151.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN84171.1 - 4.8e-30 104.8 0.5 6.3e-30 104.5 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KZN84171.1 - 1.2e-06 28.2 0.2 2.6e-06 27.1 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KZN84171.1 - 0.00018 21.0 0.0 0.00025 20.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 KZN84171.1 - 0.00032 19.9 0.0 0.00043 19.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KZN84171.1 - 0.002 18.0 0.2 0.0029 17.5 0.2 1.2 1 0 0 1 1 1 1 KR domain Transp_cyt_pur PF02133.15 KZN84174.1 - 1.4e-17 63.7 41.6 2.5e-17 62.8 41.6 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2236 PF09995.9 KZN84175.1 - 9.9e-09 35.7 0.3 1.5e-08 35.2 0.3 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Tubulin PF00091.25 KZN84176.1 - 6.1e-68 228.9 0.0 1.4e-67 227.7 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KZN84176.1 - 9.8e-43 145.3 0.0 1.7e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KZN84176.1 - 2.3e-05 24.7 0.0 6.3e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KZN84176.1 - 0.0017 17.6 0.1 0.026 13.7 0.0 2.1 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 KZN84176.1 - 0.0033 17.1 0.0 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.22 KZN84177.1 - 1.6e-13 50.3 0.0 2.7e-05 23.9 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ammonium_transp PF00909.21 KZN84178.1 - 2.6e-123 411.7 31.0 3e-123 411.5 31.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Phage_holin_2_1 PF04971.12 KZN84178.1 - 6.7 6.8 11.9 0.27 11.3 0.9 3.7 4 0 0 4 4 4 0 Bacteriophage P21 holin S Pkinase PF00069.25 KZN84180.1 - 1.3e-66 224.6 0.0 2.1e-66 224.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN84180.1 - 2.7e-36 125.2 0.0 7.8e-26 90.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KZN84180.1 - 0.00028 20.3 0.4 0.011 15.0 0.4 2.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KZN84180.1 - 0.0026 17.7 0.0 0.0067 16.4 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KZN84180.1 - 0.0044 15.8 0.0 0.0085 14.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 KZN84180.1 - 0.0096 15.0 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 FtsX_ECD PF18075.1 KZN84180.1 - 0.053 14.2 0.0 0.22 12.2 0.0 2.1 2 0 0 2 2 2 0 FtsX extracellular domain FERM_f0 PF16511.5 KZN84180.1 - 0.081 13.2 0.1 0.27 11.6 0.0 1.9 2 0 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM YrbL-PhoP_reg PF10707.9 KZN84180.1 - 0.14 11.7 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pirin PF02678.16 KZN84181.1 - 5.2e-24 84.3 0.7 1.7e-23 82.6 0.7 1.8 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.11 KZN84181.1 - 5.2e-07 29.3 1.3 3.4e-05 23.5 0.1 3.5 3 2 0 3 3 3 1 Cupin domain Vac_ImportDeg PF09783.9 KZN84182.1 - 3.5e-69 231.7 1.1 4.2e-69 231.5 1.1 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mago_nashi PF02792.14 KZN84183.1 - 2.1e-73 245.1 0.3 2.4e-73 244.9 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein PDZ_4 PF17816.1 KZN84183.1 - 0.11 12.9 0.1 3.6 8.0 0.1 2.2 1 1 0 2 2 2 0 PDZ domain Adaptin_N PF01602.20 KZN84184.1 - 2.8e-91 306.7 10.3 4.5e-91 306.0 10.3 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 KZN84184.1 - 3.3e-58 195.6 0.5 7.6e-58 194.4 0.5 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 KZN84184.1 - 4.3e-56 188.4 0.0 1.4e-55 186.7 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 KZN84184.1 - 3.7e-13 49.8 4.5 2.1e-10 40.9 0.0 3.3 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KZN84184.1 - 2.3e-09 37.5 11.1 8.9e-06 26.0 0.0 5.2 3 1 3 6 6 6 4 HEAT repeats Coatomer_g_Cpla PF16381.5 KZN84184.1 - 0.00017 21.7 0.0 0.0011 19.1 0.0 2.4 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 KZN84184.1 - 0.00021 21.3 1.2 0.65 10.4 0.1 4.8 5 0 0 5 5 4 1 HEAT repeat HEAT_EZ PF13513.6 KZN84184.1 - 0.0014 19.1 0.9 0.13 12.8 0.0 4.5 3 1 2 5 5 5 2 HEAT-like repeat AP4E_app_platf PF14807.6 KZN84184.1 - 0.0087 16.4 0.1 0.032 14.6 0.1 2.0 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform RTP1_C1 PF10363.9 KZN84184.1 - 0.009 16.2 2.8 4.6 7.5 0.3 3.7 2 1 1 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 DUF5578 PF17741.1 KZN84184.1 - 0.3 10.5 5.7 3.4 7.0 0.0 3.6 3 1 1 4 4 4 0 Family of unknown function (DUF5578) Arm PF00514.23 KZN84184.1 - 0.33 11.0 6.1 1 9.5 0.0 4.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DAGK_cat PF00781.24 KZN84185.1 - 4.2e-24 84.6 0.0 9.2e-24 83.5 0.0 1.6 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain Nop52 PF05997.12 KZN84186.1 - 4.5e-52 177.0 0.5 7.5e-51 173.0 0.5 2.1 1 1 0 1 1 1 1 Nucleolar protein,Nop52 NOT2_3_5 PF04153.18 KZN84186.1 - 0.041 14.0 0.1 0.08 13.0 0.1 1.4 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family RNA_pol_Rpc4 PF05132.14 KZN84186.1 - 0.046 14.1 0.0 0.08 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 PPL5 PF18168.1 KZN84186.1 - 0.12 11.7 0.8 0.18 11.1 0.8 1.2 1 0 0 1 1 1 0 Prim-pol family 5 RXT2_N PF08595.11 KZN84186.1 - 1.9 8.5 6.3 0.21 11.6 0.6 2.2 2 1 1 3 3 3 0 RXT2-like, N-terminal Dynactin_p62 PF05502.13 KZN84186.1 - 2.1 7.0 4.0 3.2 6.4 4.0 1.1 1 0 0 1 1 1 0 Dynactin p62 family HATPase_c PF02518.26 KZN84187.1 - 1.5e-23 83.4 0.1 3e-23 82.4 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KZN84187.1 - 3.1e-20 72.4 0.8 5.5e-20 71.6 0.8 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KZN84187.1 - 4.3e-12 45.9 0.0 2.2e-11 43.6 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 KZN84187.1 - 0.019 15.2 0.0 0.11 12.8 0.0 2.3 3 0 0 3 3 3 0 GAF domain UBD PF16455.5 KZN84188.1 - 7.7e-42 141.8 0.0 1.3e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-binding domain Rad60-SLD PF11976.8 KZN84188.1 - 0.095 12.5 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF1604 PF07713.13 KZN84189.1 - 1.2e-40 137.2 2.1 1.2e-40 137.2 2.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KZN84189.1 - 6.2e-07 29.2 3.1 1.7e-06 27.8 2.2 2.2 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KZN84189.1 - 0.021 14.9 0.6 0.021 14.9 0.6 3.6 5 1 0 5 5 5 0 G-patch domain Glyco_transf_90 PF05686.12 KZN84190.1 - 1.1e-14 54.2 4.6 1.2e-05 24.4 1.5 4.1 3 1 0 3 3 3 3 Glycosyl transferase family 90 EABR PF12180.8 KZN84190.1 - 0.024 14.3 0.2 0.045 13.4 0.2 1.4 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 APH PF01636.23 KZN84191.1 - 0.0011 19.0 0.0 0.0046 16.9 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 KZN84191.1 - 0.0058 15.9 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Fructosamine kinase SHOCT PF09851.9 KZN84191.1 - 2.5 7.9 5.5 0.42 10.4 0.4 2.2 2 0 0 2 2 2 0 Short C-terminal domain Pkinase PF00069.25 KZN84192.1 - 8.6e-26 90.9 0.0 4.3e-25 88.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN84192.1 - 0.013 14.8 0.0 0.36 10.1 0.0 2.3 2 1 0 2 2 2 0 Protein tyrosine kinase Glyco_hydro_16 PF00722.21 KZN84193.1 - 3.8e-41 140.5 4.2 3.8e-41 140.5 4.2 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 MFS_1 PF07690.16 KZN84194.1 - 8e-36 123.7 11.3 8e-36 123.7 11.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN84194.1 - 3.5e-09 36.0 5.1 3.5e-09 36.0 5.1 3.1 2 1 0 2 2 2 1 Sugar (and other) transporter Amino_oxidase PF01593.24 KZN84195.1 - 1.1e-57 196.4 0.0 5.9e-56 190.7 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KZN84195.1 - 6.5e-15 55.1 0.3 1.1e-14 54.3 0.3 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KZN84195.1 - 3.5e-08 33.0 0.3 9.8e-08 31.6 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KZN84195.1 - 4.3e-08 33.6 0.3 8.2e-07 29.5 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KZN84195.1 - 7.8e-07 28.1 0.6 1.5e-06 27.2 0.6 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KZN84195.1 - 8.4e-06 25.4 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KZN84195.1 - 2.4e-05 23.8 0.8 4.3e-05 22.9 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KZN84195.1 - 3.4e-05 23.2 0.2 6.1e-05 22.4 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KZN84195.1 - 6.1e-05 22.4 0.2 0.00013 21.3 0.2 1.5 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KZN84195.1 - 7.2e-05 22.5 4.2 0.00012 21.8 4.2 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KZN84195.1 - 0.0001 21.6 1.4 0.00017 20.8 1.4 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KZN84195.1 - 0.0011 18.2 2.6 0.0023 17.1 1.5 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A K_oxygenase PF13434.6 KZN84195.1 - 0.0015 17.7 0.4 0.83 8.7 0.1 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KZN84195.1 - 0.0045 16.3 0.1 0.008 15.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase YjeF_N PF03853.15 KZN84195.1 - 0.0095 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 YjeF-related protein N-terminus 3HCDH_N PF02737.18 KZN84195.1 - 0.024 14.5 0.2 0.041 13.8 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glu_dehyd_C PF16912.5 KZN84195.1 - 0.027 14.0 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 KZN84195.1 - 0.028 14.5 0.3 0.066 13.3 0.3 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.19 KZN84195.1 - 0.03 12.7 0.0 0.041 12.3 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like MCRA PF06100.11 KZN84195.1 - 0.079 11.7 0.0 0.73 8.6 0.0 2.0 2 0 0 2 2 2 0 MCRA family NAD_binding_9 PF13454.6 KZN84195.1 - 0.08 12.9 0.2 0.23 11.4 0.2 2.0 1 1 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KZN84195.1 - 0.14 11.1 0.3 0.21 10.6 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein UPF0146 PF03686.13 KZN84195.1 - 0.22 11.4 0.2 0.42 10.5 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) NAD_binding_7 PF13241.6 KZN84195.1 - 0.74 10.3 3.7 2.3 8.7 1.5 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding AA_permease PF00324.21 KZN84196.1 - 4.9e-103 345.3 50.7 6.1e-103 345.0 50.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KZN84196.1 - 3.6e-27 95.3 51.4 5e-27 94.8 51.4 1.1 1 0 0 1 1 1 1 Amino acid permease GMC_oxred_C PF05199.13 KZN84197.1 - 3.3e-30 105.5 0.1 5.3e-30 104.8 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KZN84197.1 - 7.4e-30 104.3 0.0 2.4e-26 92.8 0.0 2.9 1 1 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.6 KZN84197.1 - 0.0014 18.8 0.5 0.0048 17.1 0.5 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KZN84197.1 - 0.0094 15.1 0.2 0.014 14.5 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KZN84197.1 - 0.027 13.7 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KZN84197.1 - 0.027 13.5 0.0 0.038 13.0 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein BatD PF13584.6 KZN84197.1 - 0.15 10.8 0.0 0.62 8.8 0.0 1.8 2 0 0 2 2 2 0 Oxygen tolerance ApbA PF02558.16 KZN84197.1 - 0.24 11.0 0.6 0.48 10.1 0.6 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF3431 PF11913.8 KZN84199.1 - 1.6e-70 237.3 0.0 2e-70 236.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DHHA1 PF02272.19 KZN84199.1 - 0.17 12.3 0.0 0.39 11.1 0.0 1.4 1 1 0 1 1 1 0 DHHA1 domain NAD_binding_10 PF13460.6 KZN84200.1 - 6.2e-14 52.3 0.0 9.4e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KZN84200.1 - 4.5e-10 39.5 0.1 6.7e-10 38.9 0.1 1.4 1 1 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KZN84200.1 - 1.4e-06 28.6 0.0 2.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KZN84200.1 - 0.00018 21.1 0.1 0.00031 20.3 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KZN84200.1 - 0.0018 18.2 0.1 0.0028 17.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 KZN84200.1 - 0.0037 17.7 0.0 0.0066 16.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KZN84200.1 - 0.043 14.0 0.0 0.1 12.7 0.1 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus HicB PF05534.12 KZN84200.1 - 0.061 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 HicB family F420_oxidored PF03807.17 KZN84200.1 - 0.07 13.7 0.1 0.13 12.8 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 KZN84200.1 - 0.16 12.8 0.0 0.32 11.8 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.18 KZN84200.1 - 0.17 12.2 0.1 0.3 11.3 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain EI24 PF07264.11 KZN84201.1 - 4.4e-11 43.3 0.4 7.7e-11 42.6 0.4 1.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) FSH1 PF03959.13 KZN84202.1 - 1.5e-40 139.2 0.0 1.9e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF2048 PF09752.9 KZN84202.1 - 0.12 11.4 0.0 0.31 10.1 0.0 1.6 2 0 0 2 2 2 0 Abhydrolase domain containing 18 Acetyltransf_10 PF13673.7 KZN84203.1 - 1.8e-09 37.6 0.0 2.3e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KZN84203.1 - 6.6e-09 36.0 0.0 9.8e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KZN84203.1 - 6.3e-07 29.7 0.0 9.4e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KZN84203.1 - 2.6e-06 27.7 0.0 3.3e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NAD_binding_10 PF13460.6 KZN84204.1 - 1.2e-07 31.9 0.1 1.8e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KZN84204.1 - 5.9e-07 29.3 0.0 1.8e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KZN84204.1 - 4.4e-06 26.3 0.0 1.3e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family HIM1 PF08732.10 KZN84204.1 - 0.00043 19.8 0.0 0.00057 19.4 0.0 1.2 1 0 0 1 1 1 1 HIM1 Semialdhyde_dh PF01118.24 KZN84204.1 - 0.031 14.7 0.0 0.064 13.7 0.0 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KZN84204.1 - 0.057 13.5 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CAP18_C PF12153.8 KZN84204.1 - 0.27 11.1 0.1 0.27 11.1 0.1 1.7 2 0 0 2 2 2 0 LPS binding domain of CAP18 (C terminal) Glyco_transf_90 PF05686.12 KZN84205.1 - 3.3e-14 52.6 0.8 9.7e-10 37.9 0.0 3.1 3 0 0 3 3 3 3 Glycosyl transferase family 90 CRAL_TRIO PF00650.20 KZN84206.1 - 1.2e-25 90.1 0.0 2.5e-25 89.0 0.0 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KZN84206.1 - 2.3e-05 24.5 0.0 0.00023 21.3 0.0 2.4 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CDC45 PF02724.14 KZN84207.1 - 0.37 9.0 5.8 0.33 9.2 4.6 1.4 2 0 0 2 2 2 0 CDC45-like protein Goodbye PF17109.5 KZN84208.1 - 1.1e-37 129.2 0.0 5.2e-37 127.0 0.0 2.3 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain TPR_7 PF13176.6 KZN84208.1 - 2.5e-06 27.1 3.1 2 8.6 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KZN84208.1 - 3.2e-06 27.3 10.8 0.0015 18.8 1.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KZN84208.1 - 0.00031 21.3 11.0 0.24 12.3 0.0 6.0 5 1 1 6 6 5 1 Tetratricopeptide repeat NACHT PF05729.12 KZN84208.1 - 0.0021 18.0 0.0 0.011 15.6 0.0 2.3 1 1 0 1 1 1 1 NACHT domain TPR_19 PF14559.6 KZN84208.1 - 0.0024 18.3 0.1 0.0024 18.3 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 KZN84208.1 - 0.036 14.4 1.2 15 6.0 0.1 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat C1_2 PF03107.16 KZN84208.1 - 0.048 14.0 1.9 0.11 12.9 1.9 1.6 1 0 0 1 1 1 0 C1 domain PerB PF06590.11 KZN84208.1 - 0.068 13.7 0.2 0.18 12.3 0.2 1.7 1 0 0 1 1 1 0 PerB protein TPR_2 PF07719.17 KZN84208.1 - 0.088 13.0 16.5 1.5 9.1 0.1 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat ABC_tran PF00005.27 KZN84208.1 - 0.14 12.6 0.0 0.69 10.4 0.0 2.3 1 0 0 1 1 1 0 ABC transporter TPR_6 PF13174.6 KZN84208.1 - 0.16 12.6 13.4 5.3 7.9 0.0 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KZN84208.1 - 0.2 11.5 10.8 1.6 8.7 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KZN84208.1 - 2.3 8.9 7.7 14 6.5 0.0 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF1505 PF07403.11 KZN84209.1 - 0.022 14.9 0.6 0.025 14.7 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1505) Response_reg PF00072.24 KZN84210.1 - 1.2e-19 70.5 0.4 8e-19 67.9 0.5 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 KZN84210.1 - 2.7e-19 69.7 0.3 7.9e-19 68.2 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KZN84210.1 - 2.1e-10 40.5 0.0 5.5e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Acyl_transf_3 PF01757.22 KZN84211.1 - 2.8e-18 66.1 28.9 7.5e-18 64.7 28.9 1.6 1 1 0 1 1 1 1 Acyltransferase family RabGAP-TBC PF00566.18 KZN84212.1 - 1.1e-37 129.8 0.0 1e-36 126.6 0.0 2.2 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Peptidase_M64 PF09471.10 KZN84212.1 - 0.11 12.0 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 IgA Peptidase M64 Choline_transpo PF04515.12 KZN84213.1 - 1.4e-80 270.9 26.5 1.4e-80 270.9 26.5 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter Pex14_N PF04695.13 KZN84213.1 - 0.041 14.5 9.4 0.092 13.4 9.4 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Defensin_big PF14862.6 KZN84213.1 - 0.054 13.8 0.0 20 5.6 0.0 3.2 2 0 0 2 2 2 0 Big defensin DUF4229 PF14012.6 KZN84213.1 - 0.12 12.4 0.2 0.12 12.4 0.2 4.9 7 0 0 7 7 7 0 Protein of unknown function (DUF4229) DUF4956 PF16316.5 KZN84213.1 - 4.7 6.9 11.4 11 5.7 11.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4956) IL4 PF00727.18 KZN84214.1 - 0.069 13.4 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 Interleukin 4 CFEM PF05730.11 KZN84214.1 - 3 8.0 10.4 2.2 8.4 5.9 2.2 2 0 0 2 2 2 0 CFEM domain ABM PF03992.16 KZN84216.1 - 0.00051 20.1 0.1 0.00067 19.7 0.1 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase SelP_N PF04592.14 KZN84216.1 - 0.0096 15.3 0.3 0.011 15.2 0.3 1.1 1 0 0 1 1 1 1 Selenoprotein P, N terminal region DUF188 PF02639.14 KZN84216.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized BCR, YaiI/YqxD family COG1671 BCS1_N PF08740.11 KZN84217.1 - 2e-48 164.8 0.3 2.9e-48 164.3 0.3 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KZN84217.1 - 4.7e-18 65.9 0.0 8.9e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KZN84217.1 - 8.2e-05 23.1 0.1 0.0004 20.8 0.0 2.2 2 1 1 3 3 2 1 AAA ATPase domain DUF815 PF05673.13 KZN84217.1 - 0.00048 19.4 0.0 0.00078 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 KZN84217.1 - 0.0016 18.2 0.0 0.063 13.0 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_7 PF12775.7 KZN84217.1 - 0.0054 16.3 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 KZN84217.1 - 0.0055 17.3 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KZN84217.1 - 0.0082 16.5 0.0 0.027 14.8 0.0 2.0 2 0 0 2 2 1 1 RNA helicase AAA_25 PF13481.6 KZN84217.1 - 0.0082 15.7 0.0 0.17 11.5 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KZN84217.1 - 0.0086 16.1 0.0 0.026 14.5 0.0 1.9 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 KZN84217.1 - 0.021 14.5 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KZN84217.1 - 0.025 15.1 0.0 0.058 13.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_21 PF13304.6 KZN84217.1 - 0.028 14.2 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KZN84217.1 - 0.033 14.5 0.0 0.11 12.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 KZN84217.1 - 0.057 13.6 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2735 PF10931.8 KZN84217.1 - 0.076 13.7 0.1 0.19 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2735) ATPase PF06745.13 KZN84217.1 - 0.077 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 KaiC MMR_HSR1 PF01926.23 KZN84217.1 - 0.083 13.0 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase PPV_E1_C PF00519.17 KZN84217.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_11 PF13086.6 KZN84217.1 - 0.13 12.1 0.0 0.33 10.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KZN84217.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 KZN84217.1 - 0.17 11.8 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Lactamase_B_2 PF12706.7 KZN84218.1 - 3.4e-28 98.5 0.0 3.1e-27 95.4 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KZN84218.1 - 1e-10 41.8 0.0 2.7e-10 40.4 0.0 1.7 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KZN84218.1 - 0.00089 19.3 0.7 0.16 11.9 0.5 3.0 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily Cpn60_TCP1 PF00118.24 KZN84219.1 - 3.2e-174 580.2 0.4 3.6e-174 580.0 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family BRK PF07533.16 KZN84219.1 - 0.086 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 BRK domain DUF1168 PF06658.12 KZN84220.1 - 1.7e-39 134.8 7.2 2.6e-39 134.1 7.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Lyase_catalyt PF09093.11 KZN84220.1 - 0.032 13.4 0.0 0.045 12.9 0.0 1.1 1 0 0 1 1 1 0 Lyase, catalytic PPL5 PF18168.1 KZN84220.1 - 0.084 12.2 2.5 0.11 11.8 2.5 1.1 1 0 0 1 1 1 0 Prim-pol family 5 RR_TM4-6 PF06459.12 KZN84220.1 - 0.28 11.0 4.8 0.29 10.9 4.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_S49_N PF08496.10 KZN84220.1 - 0.29 11.2 4.6 0.41 10.7 4.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Presenilin PF01080.17 KZN84220.1 - 1.7 7.3 4.5 1.6 7.5 4.5 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 KZN84220.1 - 3.8 5.7 9.2 4.9 5.3 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Med19 PF10278.9 KZN84220.1 - 6 6.8 12.9 9.1 6.2 12.9 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 NARP1 PF12569.8 KZN84220.1 - 6.6 5.5 10.2 8.5 5.2 10.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 zf-PARP PF00645.18 KZN84221.1 - 2.7e-24 85.8 0.4 9.9e-24 84.0 0.4 2.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region AT_hook PF02178.19 KZN84221.1 - 0.05 13.5 16.1 0.039 13.8 3.4 3.7 2 0 0 2 2 2 0 AT hook motif FAM70 PF14967.6 KZN84222.1 - 0.42 10.0 3.2 0.69 9.3 3.2 1.2 1 0 0 1 1 1 0 FAM70 protein CENP-B_dimeris PF09026.10 KZN84222.1 - 6.1 7.3 8.0 12 6.3 8.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SPX PF03105.19 KZN84222.1 - 7.7 6.3 7.7 11 5.8 7.7 1.1 1 0 0 1 1 1 0 SPX domain BTB PF00651.31 KZN84223.1 - 1.7e-07 31.4 0.0 1.6e-06 28.3 0.0 2.4 3 0 0 3 3 3 1 BTB/POZ domain Transketolase_C PF02780.20 KZN84223.1 - 0.059 13.2 0.0 0.089 12.7 0.0 1.2 1 0 0 1 1 1 0 Transketolase, C-terminal domain Skp1_POZ PF03931.15 KZN84223.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain Lipase_3 PF01764.25 KZN84224.1 - 5.4e-16 58.7 0.0 7.8e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Phage_sheath_1N PF17481.2 KZN84224.1 - 0.0075 16.7 0.0 0.012 16.1 0.0 1.4 1 0 0 1 1 1 1 Phage tail sheath protein beta-sandwich domain MU117 PF15474.6 KZN84225.1 - 5.9e-20 71.9 4.8 1.9e-19 70.3 4.8 1.9 1 0 0 1 1 1 1 Meiotically up-regulated gene family F-box-like PF12937.7 KZN84227.1 - 0.0024 17.7 0.0 0.0056 16.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like La_HTH_kDCL PF18177.1 KZN84227.1 - 0.021 15.1 0.5 0.059 13.7 0.0 2.0 2 0 0 2 2 2 0 La HTH in kinetoplastid DICER domain Abhydrolase_6 PF12697.7 KZN84229.1 - 1.5e-14 55.1 0.4 2.3e-14 54.5 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KZN84229.1 - 5.1e-10 39.0 0.1 1.3e-09 37.7 0.2 1.6 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KZN84229.1 - 2.8e-06 27.2 0.2 4.3e-06 26.6 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KZN84229.1 - 2.9e-05 24.0 0.0 4.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KZN84229.1 - 0.0039 17.0 0.1 0.11 12.3 0.0 2.5 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KZN84229.1 - 0.0078 15.7 0.1 0.037 13.5 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 KZN84229.1 - 0.008 14.9 0.1 0.021 13.5 0.1 1.6 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Cwf_Cwc_15 PF04889.12 KZN84230.1 - 0.093 12.5 10.5 0.16 11.7 10.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2752 PF10825.8 KZN84230.1 - 0.29 11.2 2.9 0.48 10.5 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) Red1 PF07964.11 KZN84230.1 - 1.1 7.4 8.4 1.4 7.0 8.4 1.1 1 0 0 1 1 1 0 Rec10 / Red1 SURF2 PF05477.11 KZN84230.1 - 2.3 7.8 8.1 4.1 7.0 8.1 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) F-box-like PF12937.7 KZN84231.1 - 7.3e-06 25.8 0.3 0.00018 21.3 0.3 2.4 2 0 0 2 2 2 1 F-box-like CRF1 PF10380.9 KZN84232.1 - 0.055 13.8 0.1 0.055 13.8 0.1 3.2 4 0 0 4 4 4 0 Transcription factor CRF1 CFEM PF05730.11 KZN84234.1 - 0.00022 21.2 6.1 0.00022 21.2 6.1 4.4 5 0 0 5 5 5 1 CFEM domain Tme5_EGF_like PF09064.10 KZN84234.1 - 0.26 11.2 2.5 1.3 9.0 2.5 2.3 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like Epimerase PF01370.21 KZN84235.1 - 1.4e-40 139.3 0.1 1.7e-40 139.0 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KZN84235.1 - 6.5e-17 61.9 0.1 8.8e-17 61.5 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KZN84235.1 - 2.2e-14 53.2 0.0 2.9e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KZN84235.1 - 9.8e-13 47.8 0.1 2.5e-12 46.5 0.1 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KZN84235.1 - 0.0071 15.5 0.1 0.048 12.8 0.1 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KZN84235.1 - 0.0092 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KZN84235.1 - 0.037 13.2 0.1 0.29 10.3 0.0 2.1 2 1 0 2 2 2 0 Male sterility protein Pkinase PF00069.25 KZN84236.1 - 6.5e-09 35.5 0.0 1.2e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN84236.1 - 5.7e-07 29.1 0.0 9e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_72 PF03198.14 KZN84237.1 - 1.2e-99 333.5 0.1 2.5e-99 332.5 0.2 1.4 2 0 0 2 2 2 1 Glucanosyltransferase EF-hand_13 PF17958.1 KZN84238.1 - 0.16 11.8 0.0 0.44 10.4 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain Sds3 PF08598.11 KZN84240.1 - 8.5e-42 143.6 1.7 1.6e-40 139.5 1.7 2.1 1 1 0 1 1 1 1 Sds3-like CcdA PF07362.12 KZN84240.1 - 0.68 10.4 4.8 1.2 9.6 0.2 2.7 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA Hemerythrin PF01814.23 KZN84241.1 - 3.9e-11 43.7 2.0 1.2e-08 35.7 0.2 1.6 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain PP_M1 PF03012.14 KZN84244.1 - 1.6 8.2 5.9 0.39 10.2 0.3 2.0 1 1 1 2 2 2 0 Phosphoprotein Ferritin PF00210.24 KZN84247.1 - 9.6e-11 41.8 0.0 1.3e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Ferritin-like domain Pox_C4_C10 PF03336.13 KZN84247.1 - 0.19 10.8 0.0 0.26 10.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus C4/C10 protein Hva1_TUDOR PF11160.8 KZN84248.1 - 3.8e-13 49.4 0.1 6.4e-13 48.7 0.1 1.4 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain Thioredoxin_2 PF13098.6 KZN84248.1 - 0.1 13.1 0.0 0.1 13.0 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain Ras PF00071.22 KZN84249.1 - 1e-41 142.2 0.0 1.9e-41 141.4 0.0 1.4 1 0 0 1 1 1 1 Ras family Beta-lactamase PF00144.24 KZN84249.1 - 8.6e-40 137.0 0.0 1.2e-39 136.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Roc PF08477.13 KZN84249.1 - 7.1e-16 58.5 0.0 6.1e-14 52.3 0.0 2.9 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase DUF3471 PF11954.8 KZN84249.1 - 2.2e-10 40.9 0.0 4.9e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) MMR_HSR1 PF01926.23 KZN84249.1 - 0.065 13.3 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase sCache_3_2 PF17203.4 KZN84249.1 - 0.097 12.8 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Single cache domain 3 Glyco_trans_4_2 PF13477.6 KZN84249.1 - 0.19 11.8 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like TPMT PF05724.11 KZN84250.1 - 3.4e-31 108.6 0.0 4.6e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.6 KZN84250.1 - 6.5e-08 32.5 0.1 5.9e-07 29.4 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN84250.1 - 7.9e-08 32.3 0.0 1.2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN84250.1 - 1.2e-06 29.2 0.1 1e-05 26.2 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN84250.1 - 1.2e-06 29.0 0.0 2.9e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN84250.1 - 2.7e-05 24.8 0.0 4.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N2227 PF07942.12 KZN84250.1 - 0.0045 16.2 0.1 0.013 14.7 0.0 1.6 1 1 1 2 2 2 1 N2227-like protein Methyltransf_32 PF13679.6 KZN84250.1 - 0.029 14.4 0.0 0.041 13.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 KZN84250.1 - 0.039 13.5 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain TehB PF03848.14 KZN84250.1 - 0.043 13.2 0.0 0.082 12.3 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB ABC_membrane PF00664.23 KZN84251.1 - 9.5e-78 261.6 37.0 6.9e-43 147.3 16.6 3.0 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KZN84251.1 - 2.9e-67 225.4 0.0 1.9e-34 119.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KZN84251.1 - 1.7e-11 44.0 10.7 0.00063 19.3 1.1 4.7 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KZN84251.1 - 1.6e-08 34.9 1.3 0.005 17.1 0.1 4.0 3 2 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KZN84251.1 - 2.8e-08 34.3 3.3 0.00019 21.8 0.1 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KZN84251.1 - 1.7e-07 30.9 1.1 0.0074 16.0 0.5 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KZN84251.1 - 3.7e-07 30.2 0.0 0.029 14.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 KZN84251.1 - 1.1e-06 27.8 0.1 0.00033 19.6 0.1 2.6 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_15 PF13175.6 KZN84251.1 - 2.8e-05 24.0 0.0 0.025 14.3 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KZN84251.1 - 0.00017 22.0 1.0 9 6.7 0.0 4.0 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KZN84251.1 - 0.00023 20.9 1.9 1 9.1 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA_21 PF13304.6 KZN84251.1 - 0.00024 21.0 0.1 0.79 9.5 0.0 3.3 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KZN84251.1 - 0.00084 18.9 0.1 0.19 11.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_23 PF13476.6 KZN84251.1 - 0.0011 19.6 2.5 0.25 11.8 0.2 2.5 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 KZN84251.1 - 0.0013 18.0 0.1 1.4 8.0 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_25 PF13481.6 KZN84251.1 - 0.0028 17.3 0.0 2.2 7.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain DUF3465 PF11948.8 KZN84251.1 - 0.0028 17.5 0.2 0.2 11.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3465) AAA_5 PF07728.14 KZN84251.1 - 0.0033 17.4 0.0 2.5 8.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KZN84251.1 - 0.0048 17.5 1.2 1.6 9.3 0.0 3.2 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KZN84251.1 - 0.0069 16.6 1.6 1.3 9.3 0.4 3.9 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KZN84251.1 - 0.0078 16.4 2.2 3.2 7.9 0.0 3.4 3 1 1 4 4 2 1 AAA domain Zeta_toxin PF06414.12 KZN84251.1 - 0.0088 15.3 0.0 4.5 6.5 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.6 KZN84251.1 - 0.013 15.8 0.0 0.82 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KZN84251.1 - 0.014 15.3 0.0 0.15 11.9 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain PRK PF00485.18 KZN84251.1 - 0.019 14.7 0.1 6.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 KZN84251.1 - 0.043 14.2 0.0 3.2 8.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.23 KZN84251.1 - 0.051 13.7 0.1 3.7 7.7 0.0 2.9 3 0 0 3 3 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 KZN84251.1 - 0.076 13.1 0.7 1.1 9.3 0.1 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain APS_kinase PF01583.20 KZN84251.1 - 0.08 12.8 0.1 17 5.3 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase NB-ARC PF00931.22 KZN84251.1 - 0.08 12.1 0.1 3 6.9 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain SRP54 PF00448.22 KZN84251.1 - 0.085 12.5 0.0 14 5.3 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MoaE PF02391.17 KZN84251.1 - 0.11 12.8 0.7 8 6.8 0.1 2.6 2 0 0 2 2 2 0 MoaE protein ATP-synt_ab PF00006.25 KZN84251.1 - 0.13 11.9 0.0 4.1 7.0 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AMP-binding PF00501.28 KZN84252.1 - 1.5e-280 929.8 0.0 3.7e-74 249.8 0.0 4.3 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 KZN84252.1 - 3.9e-222 737.9 0.0 8.8e-48 163.1 0.0 6.9 6 2 0 6 6 6 6 Condensation domain PP-binding PF00550.25 KZN84252.1 - 1.1e-48 163.4 0.9 1.6e-10 41.2 0.0 5.7 5 0 0 5 5 5 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KZN84252.1 - 2.8e-08 34.6 0.1 2.9 8.9 0.0 5.2 4 0 0 4 4 4 3 AMP-binding enzyme C-terminal domain DUF547 PF04784.14 KZN84252.1 - 0.011 15.8 0.0 12 6.0 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function, DUF547 AAA_16 PF13191.6 KZN84253.1 - 7.7e-09 36.2 0.0 7.7e-09 36.2 0.0 3.1 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KZN84253.1 - 6.2e-06 26.5 0.7 6.6e-05 23.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 KZN84253.1 - 0.00023 21.1 0.0 0.00073 19.5 0.0 2.0 1 0 0 1 1 1 1 NACHT domain Vps39_1 PF10366.9 KZN84253.1 - 0.0064 16.8 0.9 0.42 10.9 0.2 3.6 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 TPR_12 PF13424.6 KZN84253.1 - 0.0069 16.7 13.4 0.44 10.9 0.0 6.2 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KZN84253.1 - 0.0079 16.2 1.0 51 4.2 0.0 5.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KZN84253.1 - 0.017 15.9 3.5 25 6.0 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat ABC_tran PF00005.27 KZN84253.1 - 0.025 15.1 0.5 0.3 11.6 0.0 2.9 2 0 0 2 2 2 0 ABC transporter Amidohydro_1 PF01979.20 KZN84254.1 - 1.9e-34 119.5 0.1 2.7e-34 119.0 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KZN84254.1 - 2.2e-14 53.8 3.0 7.2e-08 32.3 0.2 2.3 2 0 0 2 2 2 2 Amidohydrolase family Cyt-b5 PF00173.28 KZN84255.1 - 4e-17 62.1 0.0 7e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 KZN84255.1 - 1.6e-15 57.6 18.4 1.6e-15 57.6 18.4 2.2 2 1 0 2 2 2 1 Fatty acid desaturase p450 PF00067.22 KZN84256.1 - 9.3e-59 199.4 0.0 1.9e-58 198.3 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Mito_carr PF00153.27 KZN84257.1 - 2.4e-60 200.4 3.1 1.7e-19 69.6 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KZN84257.1 - 0.0016 17.7 0.0 0.45 9.6 0.0 2.6 2 0 0 2 2 2 2 Gammaproteobacterial serine protease Aldose_epim PF01263.20 KZN84258.1 - 5.3e-50 170.4 0.4 6.9e-50 170.0 0.4 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Cupin_2 PF07883.11 KZN84258.1 - 0.023 14.4 0.1 0.08 12.7 0.0 1.8 2 0 0 2 2 2 0 Cupin domain ACOX PF01756.19 KZN84259.1 - 4.7e-41 140.3 0.1 3.5e-40 137.5 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KZN84259.1 - 7.2e-26 91.2 1.9 1.6e-25 90.1 1.9 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KZN84259.1 - 5.8e-08 32.8 0.0 1.3e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KZN84259.1 - 0.072 13.3 0.2 0.31 11.2 0.2 2.0 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain AMP-binding PF00501.28 KZN84260.1 - 2.5e-52 177.9 0.0 3.2e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KZN84260.1 - 1e-12 48.8 0.1 2.5e-12 47.6 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ECH_1 PF00378.20 KZN84261.1 - 7.5e-24 84.4 0.0 8.6e-24 84.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KZN84261.1 - 2.2e-12 47.2 0.0 2.6e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Fungal_trans PF04082.18 KZN84262.1 - 1.9e-16 59.9 0.1 3.9e-16 58.9 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN84262.1 - 3.3e-05 23.9 11.4 7.9e-05 22.7 11.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain XPG_I PF00867.18 KZN84263.1 - 4.8e-24 84.5 0.1 2.4e-23 82.3 0.0 2.2 3 0 0 3 3 3 1 XPG I-region GEN1_C PF18380.1 KZN84263.1 - 4.1e-19 69.4 0.0 4.1e-19 69.4 0.0 2.6 2 1 1 3 3 3 1 Holliday junction resolvase Gen1 C-terminal domain XPG_N PF00752.17 KZN84263.1 - 1.6e-06 28.5 0.0 4e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain DUF92 PF01940.16 KZN84264.1 - 1.2 8.5 4.6 14 5.0 2.7 2.2 1 1 1 2 2 2 0 Integral membrane protein DUF92 DEAD PF00270.29 KZN84265.1 - 6.2e-38 130.3 0.0 1.7e-37 128.9 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KZN84265.1 - 7.2e-23 81.1 0.0 2.6e-22 79.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KZN84265.1 - 9.2e-23 80.3 0.0 1.7e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KZN84265.1 - 0.00097 19.2 0.0 0.013 15.5 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KZN84265.1 - 0.036 14.3 0.1 0.46 10.8 0.1 2.6 1 1 0 1 1 1 0 AAA domain ERCC3_RAD25_C PF16203.5 KZN84265.1 - 0.084 12.1 0.0 0.084 12.1 0.0 2.1 2 1 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase Ribosomal_L20 PF00453.18 KZN84265.1 - 3.8 7.7 10.5 8.1 6.6 10.5 1.5 1 0 0 1 1 1 0 Ribosomal protein L20 Ribosomal_S15 PF00312.22 KZN84267.1 - 3.8e-26 91.1 0.1 1.6e-25 89.1 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S15 Ribosomal_S2 PF00318.20 KZN84268.1 - 3.1e-25 88.7 0.1 4e-15 55.6 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KZN84268.1 - 1.3e-08 36.1 13.9 2.9e-08 34.9 13.9 1.6 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Ras PF00071.22 KZN84269.1 - 9e-18 64.4 0.0 1.7e-17 63.5 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KZN84269.1 - 0.0002 21.5 0.0 0.00056 20.1 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KZN84269.1 - 0.0028 16.9 0.0 0.0037 16.5 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KZN84269.1 - 0.0029 17.1 0.0 0.031 13.7 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family NACHT PF05729.12 KZN84269.1 - 0.004 17.1 0.0 0.007 16.3 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KZN84269.1 - 0.0051 17.2 0.2 0.01 16.3 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KZN84269.1 - 0.0054 17.0 0.0 0.012 15.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KZN84269.1 - 0.023 15.2 0.0 0.031 14.8 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KZN84269.1 - 0.044 13.5 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KZN84269.1 - 0.06 13.3 0.0 0.28 11.1 0.1 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 KZN84269.1 - 0.094 12.4 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KZN84269.1 - 0.097 12.2 0.2 1.3 8.6 0.1 2.1 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 KZN84269.1 - 0.11 11.5 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain RNA_helicase PF00910.22 KZN84269.1 - 0.14 12.6 0.0 0.38 11.2 0.0 1.8 1 1 0 1 1 1 0 RNA helicase Rad17 PF03215.15 KZN84269.1 - 0.14 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_5 PF07728.14 KZN84269.1 - 0.17 11.9 0.1 0.3 11.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TniB PF05621.11 KZN84269.1 - 0.17 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein DAP3 PF10236.9 KZN84269.1 - 0.2 10.8 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 PseudoU_synth_1 PF01416.20 KZN84270.1 - 2.3e-34 118.1 0.0 4.6e-33 113.9 0.0 2.5 2 0 0 2 2 2 1 tRNA pseudouridine synthase PIG-H PF10181.9 KZN84271.1 - 1.7e-25 88.6 0.2 2.9e-25 87.9 0.2 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component ubiquitin PF00240.23 KZN84272.1 - 0.0024 17.6 0.0 0.0038 17.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 KZN84272.1 - 0.0029 18.3 0.0 0.0046 17.6 0.0 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD DUF4661 PF15576.6 KZN84272.1 - 0.4 10.6 3.2 0.4 10.6 2.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4661) Pribosyl_synth PF14572.6 KZN84273.1 - 2.4e-39 135.2 2.7 2.7e-34 118.8 0.7 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KZN84273.1 - 2.8e-33 114.3 0.0 7.6e-33 112.9 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KZN84273.1 - 3e-14 52.9 0.4 5.7e-14 51.9 0.4 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KZN84273.1 - 0.0097 15.4 0.3 0.016 14.7 0.3 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF4813 PF16072.5 KZN84273.1 - 0.21 11.2 3.9 0.32 10.6 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Fe_bilin_red PF05996.12 KZN84276.1 - 0.019 14.6 0.0 0.026 14.2 0.0 1.1 1 0 0 1 1 1 0 Ferredoxin-dependent bilin reductase MFS_1 PF07690.16 KZN84277.1 - 2.5e-30 105.6 51.2 8.1e-19 67.8 23.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN84277.1 - 7.6e-08 31.6 27.4 0.0001 21.4 11.8 2.4 1 1 0 2 2 2 2 Sugar (and other) transporter Pterin_4a PF01329.19 KZN84278.1 - 2.3e-06 27.7 0.1 0.002 18.2 0.1 2.3 1 1 1 2 2 2 2 Pterin 4 alpha carbinolamine dehydratase HAD_2 PF13419.6 KZN84279.1 - 6.5e-23 81.7 0.0 8e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KZN84279.1 - 8.8e-12 45.8 0.6 7.8e-10 39.4 0.6 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KZN84279.1 - 2.5e-10 41.1 0.0 3.6e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KZN84279.1 - 1.3e-08 34.7 0.0 3e-08 33.6 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KZN84279.1 - 1.5e-05 25.0 0.0 0.0012 18.9 0.0 2.3 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 KZN84279.1 - 0.22 11.4 0.1 6.8 6.5 0.0 2.2 2 0 0 2 2 2 0 Acid Phosphatase vATP-synt_AC39 PF01992.16 KZN84280.1 - 5.1e-104 348.4 0.0 5.7e-104 348.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Nop PF01798.18 KZN84281.1 - 7.7e-83 277.5 0.0 1.7e-82 276.4 0.0 1.6 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KZN84281.1 - 6.9e-23 80.8 2.7 6.9e-23 80.8 2.7 2.9 2 0 0 2 2 2 1 NOP5NT (NUC127) domain DUF3653 PF12375.8 KZN84281.1 - 0.17 12.1 0.1 67 3.7 0.0 3.2 3 0 0 3 3 3 0 Phage protein RNA_pol_Rpb4 PF03874.16 KZN84282.1 - 2.6e-06 27.8 0.1 0.087 13.2 0.0 2.4 2 1 0 2 2 2 2 RNA polymerase Rpb4 DUF899 PF05988.12 KZN84283.1 - 1.8e-70 236.8 0.0 2.1e-70 236.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) HZS_alpha PF18582.1 KZN84283.1 - 0.00043 20.7 0.0 0.00096 19.6 0.0 1.5 1 0 0 1 1 1 1 Hydrazine synthase alpha subunit middle domain Redoxin PF08534.10 KZN84283.1 - 0.09 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Redoxin p450 PF00067.22 KZN84284.1 - 7.1e-51 173.4 0.0 8.8e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 COG5 PF10392.9 KZN84286.1 - 0.026 14.7 0.2 0.075 13.2 0.0 1.9 2 0 0 2 2 2 0 Golgi transport complex subunit 5 2CSK_N PF08521.10 KZN84286.1 - 0.051 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal TerB_C PF15615.6 KZN84286.1 - 0.2 11.9 5.5 0.71 10.2 0.1 2.8 4 0 0 4 4 4 0 TerB-C domain SKG6 PF08693.10 KZN84288.1 - 1.6e-06 27.4 0.3 3.2e-06 26.4 0.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 KZN84288.1 - 0.00063 19.9 1.9 0.0013 18.8 1.9 1.6 1 0 0 1 1 1 1 Podoplanin Abhydrolase_1 PF00561.20 KZN84289.1 - 5.1e-18 65.7 0.0 2.5e-14 53.6 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KZN84289.1 - 1.1e-09 38.0 0.0 7.6e-09 35.2 0.0 2.0 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KZN84289.1 - 1.8e-09 38.6 0.2 6.3e-09 36.8 0.1 2.0 1 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KZN84289.1 - 3.1e-06 27.3 0.0 7.5e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Ser_hydrolase PF06821.13 KZN84289.1 - 0.028 14.3 0.1 0.36 10.7 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase Ndr PF03096.14 KZN84289.1 - 0.055 12.2 0.0 0.099 11.3 0.0 1.3 1 0 0 1 1 1 0 Ndr family Muskelin_N PF06588.11 KZN84289.1 - 0.066 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Muskelin N-terminus PS_Dcarbxylase PF02666.15 KZN84290.1 - 5.4e-55 186.1 0.0 6.7e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Band_7 PF01145.25 KZN84292.1 - 7.4e-28 97.7 2.1 1.1e-27 97.1 2.1 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KZN84292.1 - 0.089 12.5 0.3 0.14 11.9 0.3 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family Cellulase PF00150.18 KZN84293.1 - 1.1e-11 44.8 0.0 1.8e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Abhydrolase_3 PF07859.13 KZN84294.1 - 5.2e-13 49.3 0.0 1e-08 35.3 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KZN84294.1 - 1.3e-08 34.6 0.0 5.7e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 KZN84294.1 - 6.5e-07 28.6 0.0 9.5e-07 28.0 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.7 KZN84294.1 - 7.1e-05 21.8 0.0 0.00014 20.9 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme AXE1 PF05448.12 KZN84294.1 - 0.0009 18.0 0.0 0.069 11.8 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 KZN84294.1 - 0.00091 18.9 0.0 0.0074 15.9 0.0 2.2 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 KZN84294.1 - 0.01 15.5 0.0 2.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Putative esterase Abhydrolase_2 PF02230.16 KZN84294.1 - 0.1 12.4 0.0 13 5.5 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Cupin_2 PF07883.11 KZN84295.1 - 1.8e-10 40.4 0.1 2.2e-08 33.7 0.1 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KZN84295.1 - 0.0042 16.8 0.0 0.18 11.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF861) AraC_binding PF02311.19 KZN84295.1 - 0.1 12.5 0.1 0.53 10.2 0.0 2.1 2 0 0 2 2 2 0 AraC-like ligand binding domain Cupin_1 PF00190.22 KZN84295.1 - 0.14 11.8 0.0 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 Cupin FAD_binding_3 PF01494.19 KZN84296.1 - 2.5e-25 89.5 0.0 3.9e-25 88.8 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KZN84296.1 - 9.5e-11 41.9 2.5 0.00013 21.7 0.0 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KZN84296.1 - 9.5e-08 31.6 0.0 4e-05 23.0 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KZN84296.1 - 8e-07 29.5 0.4 0.00016 22.2 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KZN84296.1 - 7.8e-06 25.2 3.2 1.2e-05 24.6 3.2 1.2 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 KZN84296.1 - 8.6e-06 24.9 0.7 4e-05 22.7 0.2 1.9 1 1 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.14 KZN84296.1 - 4e-05 22.5 0.9 0.00012 20.9 1.2 1.5 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 KZN84296.1 - 4.2e-05 23.7 2.0 7.7e-05 22.8 1.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KZN84296.1 - 0.0004 19.6 1.2 0.00065 18.9 1.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 KZN84296.1 - 0.00079 18.7 0.2 0.0012 18.1 0.2 1.2 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KZN84296.1 - 0.0009 18.4 0.5 0.0081 15.2 0.5 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 KZN84296.1 - 0.0018 17.7 2.6 0.0025 17.2 2.6 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.10 KZN84296.1 - 0.0087 15.1 0.0 0.038 13.0 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase Amino_oxidase PF01593.24 KZN84296.1 - 0.015 14.6 0.1 5.1 6.3 0.4 2.8 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 KZN84296.1 - 0.022 14.1 2.1 0.039 13.2 2.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KZN84296.1 - 0.025 14.5 0.6 0.039 13.8 0.6 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KZN84296.1 - 0.068 12.4 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KZN84296.1 - 0.1 12.2 0.2 0.17 11.4 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Zn_clus PF00172.18 KZN84297.1 - 2.9e-09 36.9 9.1 5.7e-09 36.0 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN84297.1 - 0.03 13.3 0.2 0.057 12.5 0.2 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Bac_luciferase PF00296.20 KZN84298.1 - 3.4e-59 200.8 0.8 4.8e-59 200.3 0.8 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase HNH_repeat PF18780.1 KZN84298.1 - 0.064 13.1 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Homing endonuclease repeat Methyltrn_RNA_3 PF02598.17 KZN84298.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methyltransferase FMO-like PF00743.19 KZN84299.1 - 1.9e-15 56.3 0.3 2.1e-12 46.2 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KZN84299.1 - 2.4e-08 33.6 0.0 3.5e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN84299.1 - 2e-06 28.0 0.0 5.3e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KZN84299.1 - 2.8e-05 23.5 0.6 0.00015 21.2 0.6 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KZN84299.1 - 0.0001 21.6 0.1 0.00041 19.6 0.1 1.9 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DnaB_2 PF07261.11 KZN84299.1 - 0.11 12.3 0.5 17 5.2 0.1 2.4 2 0 0 2 2 2 0 Replication initiation and membrane attachment AlaDh_PNT_C PF01262.21 KZN84299.1 - 0.2 11.0 0.0 0.55 9.5 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KZN84299.1 - 0.23 10.5 0.1 12 4.8 0.1 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A adh_short PF00106.25 KZN84300.1 - 3.5e-27 95.2 0.0 1.7e-24 86.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KZN84300.1 - 2.3e-19 69.9 0.0 9.4e-18 64.6 0.0 2.1 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN84300.1 - 4.7e-09 36.4 0.0 1.1e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KZN84300.1 - 3.5e-05 23.4 0.0 4.9e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KZN84300.1 - 0.032 14.1 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KZN84300.1 - 0.041 14.6 0.0 0.14 12.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Catalase PF00199.19 KZN84301.1 - 2.8e-145 484.3 0.0 3.8e-145 483.8 0.0 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KZN84301.1 - 1.8e-13 50.5 0.0 3.3e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive Acetyltransf_1 PF00583.25 KZN84302.1 - 3.2e-10 40.3 0.0 4.3e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KZN84302.1 - 4.3e-07 29.9 0.0 6e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KZN84302.1 - 6.1e-07 29.8 0.0 1.1e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KZN84302.1 - 0.0018 18.2 0.0 0.0029 17.5 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KZN84302.1 - 0.16 12.1 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase adh_short PF00106.25 KZN84303.1 - 2.6e-14 53.2 0.0 4.9e-14 52.3 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN84303.1 - 1.4e-12 47.7 0.0 1.8e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN84303.1 - 0.00012 22.1 0.1 0.00088 19.2 0.1 1.9 1 1 0 1 1 1 1 KR domain F-box-like PF12937.7 KZN84304.1 - 3.9e-05 23.5 1.3 9.2e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KZN84304.1 - 5.9e-05 22.8 0.3 0.0058 16.5 0.0 2.8 3 0 0 3 3 3 1 F-box domain Rhomboid_SP PF12595.8 KZN84304.1 - 0.0016 17.9 0.2 0.0029 17.0 0.2 1.3 1 0 0 1 1 1 1 Rhomboid serine protease Sulfate_transp PF00916.20 KZN84305.1 - 9e-71 238.6 17.4 1.2e-70 238.2 17.4 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KZN84305.1 - 2.7e-15 56.0 0.0 4.5e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KZN84305.1 - 2.6e-05 24.5 0.0 0.00015 22.1 0.0 2.3 2 0 0 2 2 2 1 STAS domain MFS_MOT1 PF16983.5 KZN84305.1 - 0.15 12.5 15.6 0.039 14.4 5.0 2.8 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily EIF_2_alpha PF07541.12 KZN84306.1 - 9.3e-38 128.9 0.0 1.8e-37 128.0 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KZN84306.1 - 1.7e-07 31.4 0.2 4.9e-07 30.0 0.2 1.9 1 1 0 1 1 1 1 S1 RNA binding domain PKD_channel PF08016.12 KZN84307.1 - 9.4e-07 27.8 22.8 1.3e-05 24.1 21.3 2.5 1 1 0 1 1 1 1 Polycystin cation channel E1-E2_ATPase PF00122.20 KZN84308.1 - 3.8e-19 68.9 0.0 2.4e-18 66.3 0.0 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KZN84308.1 - 3.2e-14 53.7 2.1 3.9e-08 33.8 1.3 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KZN84308.1 - 0.0011 19.0 0.0 0.034 14.2 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KZN84308.1 - 0.0059 16.4 0.1 0.033 13.9 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KZN84308.1 - 0.086 12.4 0.1 0.27 10.7 0.0 1.8 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Mt_ATP-synt_B PF05405.14 KZN84308.1 - 0.52 9.9 4.4 9.8 5.8 0.1 2.6 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) AA_permease_2 PF13520.6 KZN84309.1 - 9.6e-49 166.3 52.4 1.4e-48 165.8 52.4 1.3 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN84309.1 - 7.9e-17 61.0 43.8 3.9e-15 55.4 43.8 2.1 1 1 0 1 1 1 1 Amino acid permease DUF5480 PF17576.2 KZN84309.1 - 2.7 8.0 10.4 1.2 9.2 0.5 3.5 3 1 0 3 3 3 0 Family of unknown function (DUF5480) CinA PF02464.17 KZN84310.1 - 1e-42 145.3 0.2 1.2e-42 145.1 0.2 1.1 1 0 0 1 1 1 1 Competence-damaged protein Aldo_ket_red PF00248.21 KZN84311.1 - 1.3e-12 47.6 0.0 1.9e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Kdo PF06293.14 KZN84312.1 - 1.5e-09 37.5 0.0 4.4e-09 36.0 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KZN84312.1 - 2e-08 34.5 0.1 0.00053 20.0 0.1 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KZN84312.1 - 1.1e-07 31.6 0.0 1.5e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KZN84312.1 - 0.0053 16.4 0.0 0.69 9.5 0.0 2.4 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 KZN84312.1 - 0.0078 15.0 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KZN84312.1 - 0.013 14.8 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase AP_endonuc_2 PF01261.24 KZN84312.1 - 0.03 13.8 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Zn_clus PF00172.18 KZN84313.1 - 3.4e-09 36.7 7.8 8.7e-09 35.4 7.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CoiA PF06054.11 KZN84313.1 - 0.034 13.3 1.5 0.034 13.3 0.0 1.6 2 0 0 2 2 2 0 Competence protein CoiA-like family CALCOCO1 PF07888.11 KZN84313.1 - 0.26 10.1 0.1 4.9 5.9 0.0 2.1 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like RNA_pol_Rpb1_1 PF04997.12 KZN84314.1 - 4e-85 285.9 0.1 6.7e-85 285.2 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KZN84314.1 - 2.6e-78 263.1 0.2 3.8e-78 262.6 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KZN84314.1 - 2.3e-72 242.6 0.1 6.7e-72 241.1 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KZN84314.1 - 2.4e-34 118.5 0.0 6.5e-33 113.9 0.0 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KZN84314.1 - 1.6e-27 95.6 0.1 4.2e-27 94.2 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Rpr2 PF04032.16 KZN84314.1 - 1.2 9.5 4.5 1 9.7 1.9 2.3 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain GTP_EFTU PF00009.27 KZN84315.1 - 8.2e-50 169.0 0.0 1.2e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KZN84315.1 - 4.1e-43 145.9 3.4 7e-43 145.1 3.4 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KZN84315.1 - 1.9e-18 66.3 0.0 4.3e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 KZN84315.1 - 2.8e-05 24.2 0.0 6.4e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KZN84315.1 - 0.00029 20.5 0.0 0.0006 19.4 0.0 1.5 1 0 0 1 1 1 1 Ras family EFG_II PF14492.6 KZN84315.1 - 0.00049 20.1 0.0 0.0013 18.7 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KZN84315.1 - 0.0008 19.8 0.1 0.002 18.5 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.10 KZN84315.1 - 0.0041 16.6 0.0 0.0085 15.5 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RF3_C PF16658.5 KZN84315.1 - 0.0086 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Snurportin1 PF11538.8 KZN84315.1 - 0.22 11.7 2.3 0.58 10.4 2.3 1.6 1 0 0 1 1 1 0 Snurportin1 HORMA PF02301.18 KZN84316.1 - 4.3e-34 118.0 0.1 5e-34 117.8 0.1 1.0 1 0 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 KZN84316.1 - 0.023 14.5 0.1 0.049 13.5 0.0 1.6 2 0 0 2 2 2 0 Bacterial HORMA domain 2 DUF218 PF02698.17 KZN84317.1 - 1.9e-05 24.7 0.0 2.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain Serglycin PF04360.12 KZN84318.1 - 0.059 13.3 0.0 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 Serglycin DUF3040 PF11239.8 KZN84318.1 - 5.9 7.2 6.1 19 5.6 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) zf-CCCH_4 PF18044.1 KZN84321.1 - 1.1e-07 31.5 3.1 2.3e-07 30.4 3.1 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KZN84321.1 - 2e-07 30.8 6.2 4.1e-07 29.8 6.2 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KZN84321.1 - 7e-05 22.6 1.1 0.00012 21.8 1.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KZN84321.1 - 0.0051 17.5 0.1 0.0051 17.5 0.1 2.1 2 0 0 2 2 2 1 Torus domain zf-CCCH_2 PF14608.6 KZN84321.1 - 0.0067 16.9 2.9 0.012 16.0 2.9 1.5 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KZN84321.1 - 0.014 15.6 0.2 0.028 14.6 0.2 1.5 1 0 0 1 1 1 0 Zinc-finger containing family 14-3-3 PF00244.20 KZN84321.1 - 0.1 12.1 0.3 0.19 11.2 0.3 1.3 1 0 0 1 1 1 0 14-3-3 protein Sec1 PF00995.23 KZN84322.1 - 1.6e-127 427.2 0.0 1.9e-127 427.0 0.0 1.1 1 0 0 1 1 1 1 Sec1 family FYVE PF01363.21 KZN84324.1 - 2e-23 82.3 25.4 3.1e-17 62.5 5.2 3.0 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 KZN84324.1 - 1e-17 63.6 2.4 1.4e-17 63.2 0.7 2.1 2 0 0 2 2 2 1 Rabenosyn Rab binding domain zf-Di19 PF05605.12 KZN84324.1 - 0.0014 18.9 7.6 0.12 12.7 0.1 2.8 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.16 KZN84324.1 - 0.0019 18.3 6.2 0.0019 18.3 6.2 3.8 3 1 1 4 4 4 1 AN1-like Zinc finger YqaH PF17448.2 KZN84324.1 - 0.014 15.7 0.2 0.037 14.3 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized YqaH-like TMF_TATA_bd PF12325.8 KZN84324.1 - 0.015 15.5 3.7 0.015 15.5 0.7 2.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding IBR PF01485.21 KZN84324.1 - 0.024 14.8 3.9 0.024 14.8 3.9 3.3 4 0 0 4 4 4 0 IBR domain, a half RING-finger domain zf-WRNIP1_ubi PF18279.1 KZN84324.1 - 0.23 12.2 4.7 2.9 8.8 0.3 2.9 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain UBZ_FAAP20 PF15750.5 KZN84324.1 - 0.46 10.5 4.6 8 6.5 0.4 2.9 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger GLTP PF08718.11 KZN84326.1 - 1.7e-46 158.2 0.0 2.2e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) MIP-T3 PF10243.9 KZN84326.1 - 0.02 14.9 0.1 0.036 14.1 0.1 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CH-like domain CwsA PF10814.8 KZN84326.1 - 0.071 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA Cir_N PF10197.9 KZN84326.1 - 0.099 12.9 0.6 0.16 12.2 0.0 1.6 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR PH_4 PF15404.6 KZN84327.1 - 2.6e-54 183.8 0.2 2.1e-53 180.9 0.2 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain Spo7_2_N PF15407.6 KZN84327.1 - 3.7e-25 87.3 0.8 9.4e-25 86.0 0.8 1.8 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.29 KZN84327.1 - 5.5e-09 36.5 0.1 0.0054 17.2 0.0 5.1 4 1 0 4 4 4 2 PH domain DUF1654 PF07867.11 KZN84327.1 - 0.096 12.4 0.2 0.31 10.8 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) Peptidase_S24 PF00717.23 KZN84328.1 - 1.1e-07 31.7 0.1 8.7e-07 28.8 0.1 2.1 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KZN84328.1 - 0.028 14.2 0.0 7.1 6.4 0.0 2.5 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 Macro PF01661.21 KZN84329.1 - 7e-41 139.0 0.0 9.6e-41 138.5 0.0 1.2 1 0 0 1 1 1 1 Macro domain GATA PF00320.27 KZN84330.1 - 3.1e-15 55.5 5.3 5.8e-15 54.6 5.3 1.5 1 0 0 1 1 1 1 GATA zinc finger zinc_ribbon_9 PF14369.6 KZN84330.1 - 0.39 11.0 1.6 0.86 9.9 1.6 1.5 1 0 0 1 1 1 0 zinc-ribbon COesterase PF00135.28 KZN84331.1 - 3.7e-99 332.9 0.1 4.8e-99 332.5 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KZN84331.1 - 1.8e-05 24.7 0.3 0.0052 16.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KZN84331.1 - 0.0073 15.8 0.2 0.013 15.0 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family GCS PF03074.16 KZN84333.1 - 1.6e-176 587.1 0.0 1.9e-176 586.8 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase DUF1560 PF07597.11 KZN84333.1 - 0.11 12.5 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1560) Cytochrom_B561 PF03188.16 KZN84333.1 - 0.23 11.6 0.0 6.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 NDUF_B7 PF05676.13 KZN84334.1 - 1e-29 102.1 6.9 1.2e-29 101.8 6.9 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 KZN84334.1 - 0.011 15.7 3.0 0.016 15.2 3.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ank_2 PF12796.7 KZN84335.1 - 5.8e-10 39.6 0.5 0.00093 19.7 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN84335.1 - 6.9e-09 36.1 0.3 0.0002 21.9 0.1 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KZN84335.1 - 3.3e-08 33.6 0.7 7e-05 23.0 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN84335.1 - 1.3e-07 31.3 0.6 0.0022 18.3 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 KZN84335.1 - 3e-07 30.6 2.1 1.1e-05 25.6 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeat KilA-N PF04383.13 KZN84335.1 - 2.3e-05 24.2 0.1 0.0002 21.1 0.0 2.5 2 0 0 2 2 2 1 KilA-N domain RskA PF10099.9 KZN84335.1 - 0.0026 18.1 3.8 0.0026 18.1 3.8 2.2 3 0 0 3 3 3 1 Anti-sigma-K factor rskA HALZ PF02183.18 KZN84335.1 - 0.041 14.1 4.3 4.6 7.5 0.1 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper TrmB PF01978.19 KZN84335.1 - 0.13 12.1 0.1 9.6 6.2 0.1 3.1 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB ThrE PF06738.12 KZN84337.1 - 3e-75 252.7 16.8 3e-68 229.8 5.0 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KZN84337.1 - 3.7e-10 40.0 9.8 3.7e-10 40.0 9.8 3.0 3 1 0 3 3 3 1 Threonine/Serine exporter, ThrE NMN_transporter PF04973.12 KZN84337.1 - 1.5 8.8 5.9 46 3.9 5.9 2.4 1 1 0 1 1 1 0 Nicotinamide mononucleotide transporter MIS13 PF08202.11 KZN84338.1 - 5.8e-44 150.6 1.1 1.2e-43 149.6 1.1 1.6 1 0 0 1 1 1 1 Mis12-Mtw1 protein family AT_hook PF02178.19 KZN84338.1 - 0.014 15.2 14.0 0.78 9.8 2.9 3.5 2 0 0 2 2 2 0 AT hook motif PS_Dcarbxylase PF02666.15 KZN84339.1 - 2.5e-53 180.6 0.0 3.8e-53 180.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 KZN84339.1 - 6e-37 126.1 0.0 4.1e-17 62.4 0.0 2.4 2 0 0 2 2 2 2 C2 domain EF-hand_1 PF00036.32 KZN84339.1 - 0.032 13.8 0.1 0.14 11.7 0.1 2.2 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 KZN84339.1 - 0.13 12.7 0.4 0.73 10.3 0.4 2.3 1 0 0 1 1 1 0 EF-hand domain pair Sugar_tr PF00083.24 KZN84340.1 - 1.5e-89 301.0 13.7 1.9e-89 300.6 13.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN84340.1 - 3.3e-36 125.0 60.4 4.1e-32 111.5 34.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KZN84340.1 - 3.7e-06 26.5 4.4 3.7e-06 26.5 4.4 2.5 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KZN84340.1 - 0.2 9.9 6.9 0.041 12.2 2.1 2.5 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 KZN84340.1 - 4.3 5.6 15.3 0.014 13.9 1.8 2.0 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Pkinase PF00069.25 KZN84341.1 - 5.4e-64 216.1 0.0 6.6e-64 215.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN84341.1 - 6.6e-30 104.2 0.0 9.9e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KZN84341.1 - 0.0033 16.4 0.0 0.0042 16.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KZN84341.1 - 0.18 11.7 0.0 1.1 9.1 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-UBR PF02207.20 KZN84342.1 - 2.6e-13 49.9 8.4 2.6e-13 49.9 8.4 3.5 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) RR_TM4-6 PF06459.12 KZN84342.1 - 7.8 6.2 8.5 15 5.3 8.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MCM PF00493.23 KZN84343.1 - 5.3e-100 333.1 0.0 8e-100 332.5 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KZN84343.1 - 1e-37 128.8 0.2 1.9e-37 127.9 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 KZN84343.1 - 2.2e-30 106.0 38.3 2.2e-30 106.0 38.3 2.1 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 KZN84343.1 - 1.3e-23 83.2 0.7 1.3e-23 83.2 0.7 2.0 2 0 0 2 2 1 1 MCM AAA-lid domain MCM_N PF14551.6 KZN84343.1 - 2.1e-13 50.7 0.1 8.8e-13 48.8 0.1 2.1 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KZN84343.1 - 7.2e-08 32.1 0.0 7.1e-06 25.6 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KZN84343.1 - 0.00011 22.3 0.0 0.00024 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KZN84343.1 - 0.0044 16.7 0.2 0.032 13.9 0.2 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 KZN84343.1 - 0.014 15.3 0.1 0.15 11.9 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zn_ribbon_2 PF12674.7 KZN84343.1 - 0.027 15.1 0.2 0.084 13.5 0.2 1.8 1 0 0 1 1 1 0 Putative zinc ribbon domain AAA_16 PF13191.6 KZN84343.1 - 5.1 7.5 7.5 1.3 9.4 0.8 3.4 3 1 0 3 3 3 0 AAA ATPase domain Pal1 PF08316.11 KZN84344.1 - 3.6e-46 157.3 1.7 4.3e-45 153.8 1.7 2.6 1 1 0 1 1 1 1 Pal1 cell morphology protein DUF2250 PF10007.9 KZN84346.1 - 0.0071 16.4 1.3 0.016 15.3 1.3 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) Corona_M PF01635.18 KZN84346.1 - 0.14 11.4 0.1 0.2 11.0 0.1 1.2 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein Med31 PF05669.12 KZN84347.1 - 2.4e-31 107.6 0.0 2.9e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 SOH1 Palm_thioest PF02089.15 KZN84349.1 - 1.3e-83 280.6 0.0 1.6e-83 280.3 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 KZN84349.1 - 0.044 13.1 0.0 0.093 12.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) HTH_18 PF12833.7 KZN84349.1 - 0.14 12.4 0.0 32 4.9 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain GluR_Homer-bdg PF10606.9 KZN84350.1 - 0.049 13.8 3.6 0.093 12.9 0.7 2.6 2 1 0 2 2 2 0 Homer-binding domain of metabotropic glutamate receptor zf-C2H2 PF00096.26 KZN84351.1 - 0.042 14.3 0.5 4 8.1 0.0 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type KTI12 PF08433.10 KZN84352.1 - 2.4e-66 224.0 0.0 4e-66 223.3 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KZN84352.1 - 0.0027 17.9 0.3 0.0065 16.6 0.3 1.6 1 0 0 1 1 1 1 AAA domain Methyltransf_16 PF10294.9 KZN84353.1 - 6.5e-15 55.3 0.0 1.1e-14 54.5 0.0 1.3 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KZN84353.1 - 0.0029 17.5 0.0 0.0046 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Sugar_tr PF00083.24 KZN84355.1 - 1.2e-87 294.7 21.1 1.5e-87 294.4 21.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN84355.1 - 2.6e-14 52.9 47.9 3.3e-13 49.3 22.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nup84_Nup100 PF04121.13 KZN84355.1 - 0.33 9.0 0.6 0.5 8.4 0.1 1.4 2 0 0 2 2 2 0 Nuclear pore protein 84 / 107 Peptidase_C14 PF00656.22 KZN84357.1 - 5.1e-61 206.8 0.0 6.7e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.18 KZN84357.1 - 0.23 11.0 0.6 7.1 6.1 0.1 2.3 1 1 1 2 2 2 0 Peptidase C13 family F-box_4 PF15966.5 KZN84358.1 - 0.00039 20.3 0.0 0.0007 19.5 0.0 1.4 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 KZN84358.1 - 0.0074 16.2 0.0 0.023 14.6 0.0 1.9 1 0 0 1 1 1 1 F-box-like DUF3712 PF12505.8 KZN84359.1 - 1.9e-29 102.5 0.3 4.1e-29 101.4 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) DUF2236 PF09995.9 KZN84360.1 - 3.5e-39 135.3 2.4 4.6e-39 135.0 2.4 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) MDMPI_C PF07398.11 KZN84360.1 - 0.072 14.0 0.2 0.23 12.3 0.0 2.0 2 0 0 2 2 2 0 MDMPI C-terminal domain IDO PF01231.18 KZN84362.1 - 1.3e-162 541.5 0.0 1.7e-162 541.1 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase CsbD PF05532.12 KZN84362.1 - 1.5e-14 53.6 23.1 5.4e-10 39.0 6.0 3.0 3 0 0 3 3 3 2 CsbD-like COesterase PF00135.28 KZN84363.1 - 2.2e-16 59.8 0.2 1.3e-10 40.8 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Esterase_phd PF10503.9 KZN84363.1 - 0.00057 19.4 0.1 0.00062 19.3 0.1 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 KZN84363.1 - 0.042 13.6 0.0 0.052 13.4 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KZN84363.1 - 0.051 14.2 0.2 0.053 14.1 0.2 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 KZN84363.1 - 0.14 12.0 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) Aminotran_5 PF00266.19 KZN84364.1 - 2.5e-91 306.4 0.0 3e-91 306.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KZN84364.1 - 0.0013 18.1 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KZN84364.1 - 0.0033 16.8 0.0 0.017 14.5 0.0 2.0 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family BAR PF03114.18 KZN84365.1 - 2.3e-64 217.3 9.5 3e-64 216.9 9.5 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KZN84365.1 - 1e-13 50.7 0.1 2e-13 49.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KZN84365.1 - 2.9e-11 43.0 0.1 4.8e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KZN84365.1 - 5.3e-08 32.4 0.1 1.5e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain TMPIT PF07851.13 KZN84365.1 - 0.036 13.3 7.0 0.18 11.0 0.1 2.2 1 1 1 2 2 2 0 TMPIT-like protein CT_C_D PF02682.16 KZN84365.1 - 0.077 12.7 0.4 0.14 11.9 0.4 1.4 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D Zn_dep_PLPC PF00882.18 KZN84365.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Zinc dependent phospholipase C YlqD PF11068.8 KZN84365.1 - 0.24 11.8 5.5 0.29 11.5 0.0 2.8 3 0 0 3 3 3 0 YlqD protein BAR_3 PF16746.5 KZN84365.1 - 0.56 9.9 10.7 2.9 7.6 10.7 2.2 1 1 0 1 1 1 0 BAR domain of APPL family BRE1 PF08647.11 KZN84365.1 - 3.7 7.7 12.8 2 8.5 0.3 2.7 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase STE2 PF02116.15 KZN84366.1 - 2.1e-106 355.4 23.2 2.5e-106 355.1 23.2 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DUF2929 PF11151.8 KZN84366.1 - 0.041 14.2 1.5 0.041 14.2 1.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) CcmD PF04995.14 KZN84366.1 - 0.68 10.1 12.5 1 9.5 0.1 3.6 3 1 0 3 3 3 0 Heme exporter protein D (CcmD) UEV PF05743.13 KZN84367.1 - 2e-38 131.0 0.1 3.6e-38 130.1 0.1 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 KZN84367.1 - 3.9e-20 71.5 0.0 1.1e-19 70.2 0.0 1.8 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.26 KZN84367.1 - 0.1 12.3 0.0 0.1 12.3 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-conjugating enzyme DUF3450 PF11932.8 KZN84367.1 - 0.19 11.0 2.2 0.32 10.3 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Alpha_GJ PF03229.13 KZN84367.1 - 3 8.4 12.5 0.87 10.1 7.7 2.5 1 1 1 2 2 2 0 Alphavirus glycoprotein J Opy2 PF09463.10 KZN84368.1 - 2.9e-08 33.9 23.2 5.4e-08 33.0 23.2 1.5 1 0 0 1 1 1 1 Opy2 protein SKG6 PF08693.10 KZN84368.1 - 0.0053 16.1 1.8 0.012 15.0 1.8 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain BT1 PF03092.16 KZN84368.1 - 0.023 13.0 0.0 0.024 12.9 0.0 1.1 1 0 0 1 1 1 0 BT1 family Syndecan PF01034.20 KZN84368.1 - 0.056 13.4 0.0 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain PIRT PF15099.6 KZN84368.1 - 0.27 10.8 1.6 0.49 10.0 0.0 2.2 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family Hamartin PF04388.12 KZN84368.1 - 1.4 7.5 6.7 2 7.0 6.7 1.2 1 0 0 1 1 1 0 Hamartin protein Chitin_synth_1 PF01644.17 KZN84369.1 - 3e-69 232.2 0.0 4.3e-69 231.7 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KZN84369.1 - 2e-28 98.1 0.0 3.9e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KZN84369.1 - 3.6e-24 85.3 0.0 6.2e-20 71.3 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KZN84369.1 - 9.9e-11 41.9 1.0 4.8e-10 39.7 0.0 2.6 3 0 0 3 3 3 1 Glycosyl transferase family group 2 UQ_con PF00179.26 KZN84370.1 - 3.6e-38 130.4 0.0 5.2e-38 129.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KZN84370.1 - 0.097 12.5 0.0 0.4 10.6 0.0 1.9 2 0 0 2 2 2 0 UEV domain Prok-E2_B PF14461.6 KZN84370.1 - 0.16 11.7 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B COX6C PF02937.15 KZN84371.1 - 0.0074 16.4 0.0 0.0085 16.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIc TAF8_C PF10406.9 KZN84372.1 - 3.3e-20 72.4 0.0 7.7e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 KZN84372.1 - 1e-08 35.1 0.0 1.7e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated PAP2 PF01569.21 KZN84372.1 - 0.18 11.6 0.2 0.29 10.9 0.2 1.3 1 0 0 1 1 1 0 PAP2 superfamily Mitochondr_Som1 PF11093.8 KZN84373.1 - 1.5e-23 82.5 0.0 1.9e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Rad51 PF08423.11 KZN84374.1 - 3.1e-07 29.9 0.0 7.3e-05 22.2 0.0 2.3 2 1 0 2 2 2 2 Rad51 PALP PF00291.25 KZN84375.1 - 5.4e-71 239.4 0.2 8.3e-71 238.8 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KZN84375.1 - 0.042 13.2 0.1 0.065 12.5 0.1 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family IlvN PF07991.12 KZN84376.1 - 3.7e-45 153.5 0.0 5.5e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KZN84376.1 - 1.2e-39 135.9 0.0 1.9e-39 135.2 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 KZN84376.1 - 0.03 14.5 0.0 0.053 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Isochorismatase PF00857.20 KZN84377.1 - 1.3e-25 90.5 0.0 3.2e-25 89.3 0.0 1.7 1 1 0 1 1 1 1 Isochorismatase family 2OG-FeII_Oxy_2 PF13532.6 KZN84377.1 - 2.4e-25 89.9 0.0 4.1e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GST_C_2 PF13410.6 KZN84377.1 - 2e-05 24.5 0.0 5.9e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KZN84377.1 - 0.077 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KZN84377.1 - 0.15 12.5 0.0 0.45 11.0 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Glutaredoxin2_C PF04399.13 KZN84377.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Lipase_GDSL_2 PF13472.6 KZN84378.1 - 8.3e-12 45.9 0.2 1e-11 45.6 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KZN84378.1 - 7.2e-08 32.6 0.0 8.8e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ECH_1 PF00378.20 KZN84379.1 - 1.6e-40 139.0 0.0 4.3e-40 137.6 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KZN84379.1 - 1.8e-32 113.2 0.0 3.8e-31 108.8 0.0 1.8 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase HSP20 PF00011.21 KZN84380.1 - 1.8e-18 66.5 0.1 1.3e-17 63.8 0.1 2.0 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KZN84380.1 - 2.8e-06 26.8 0.0 1e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Tfb5 PF06331.12 KZN84381.1 - 8.4e-22 76.9 1.6 1e-21 76.6 1.6 1.2 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DIOX_N PF14226.6 KZN84382.1 - 4.1e-27 95.3 0.0 4.2e-25 88.8 0.0 2.2 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KZN84382.1 - 4e-13 49.7 0.0 6.3e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_12 PF13424.6 KZN84385.1 - 1.8e-30 105.0 13.2 5.1e-12 45.9 0.2 6.0 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 KZN84385.1 - 2.8e-14 52.4 22.5 0.023 14.5 0.1 7.9 8 1 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 KZN84385.1 - 1.7e-06 27.8 3.5 0.5 10.7 0.1 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat PGAP1 PF07819.13 KZN84385.1 - 6.1e-06 26.1 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 KZN84385.1 - 0.00054 19.5 0.1 0.0017 17.9 0.1 1.9 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KZN84385.1 - 0.0013 19.4 0.1 0.0041 17.8 0.0 1.9 2 0 0 2 2 1 1 Alpha/beta hydrolase family ANAPC3 PF12895.7 KZN84385.1 - 0.0021 18.2 2.3 0.28 11.5 0.5 3.1 3 0 0 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KZN84385.1 - 0.0043 17.0 5.1 2 8.6 0.2 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KZN84385.1 - 0.0051 16.2 13.7 0.0077 15.7 9.3 2.8 1 1 2 3 3 3 2 MalT-like TPR region TPR_2 PF07719.17 KZN84385.1 - 0.015 15.4 7.6 0.12 12.6 0.5 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KZN84385.1 - 0.022 15.2 9.0 8.8 6.9 0.3 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KZN84385.1 - 0.024 15.3 7.5 1.6 9.5 0.1 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat Hydrolase_4 PF12146.8 KZN84385.1 - 0.041 13.1 0.0 0.094 12.0 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 TPR_1 PF00515.28 KZN84385.1 - 0.05 13.4 8.2 0.46 10.4 0.4 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat Cutinase PF01083.22 KZN84385.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Cutinase Palm_thioest PF02089.15 KZN84385.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase FANCAA PF15146.6 KZN84385.1 - 0.24 10.5 1.7 5.2 6.0 0.3 2.3 2 0 0 2 2 2 0 Fanconi anemia-associated TPR_14 PF13428.6 KZN84385.1 - 0.36 11.8 8.8 3.9 8.6 0.2 5.2 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KZN84385.1 - 1 10.1 6.0 1.5 9.5 0.4 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat SLAC1 PF03595.17 KZN84386.1 - 1.1e-82 277.9 45.7 1.2e-82 277.8 45.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Glyco_hydro_43 PF04616.14 KZN84387.1 - 1.3e-36 126.4 3.8 1.6e-36 126.1 3.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Fungal_trans PF04082.18 KZN84388.1 - 4.3e-14 52.2 0.0 8.7e-14 51.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN84388.1 - 3.2e-05 24.0 8.9 5.5e-05 23.2 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SlyX PF04102.12 KZN84388.1 - 0.36 11.5 3.4 0.2 12.3 0.5 2.1 2 0 0 2 2 2 0 SlyX Cu_amine_oxid PF01179.20 KZN84389.1 - 2.1e-164 547.4 0.1 2.5e-164 547.1 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KZN84389.1 - 0.00016 22.1 0.0 0.00031 21.1 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KZN84389.1 - 0.0048 17.1 0.1 0.0098 16.1 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain AA_permease_2 PF13520.6 KZN84390.1 - 2.6e-64 217.7 49.1 3e-64 217.4 49.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN84390.1 - 7.1e-24 84.2 40.7 9.4e-24 83.8 40.7 1.1 1 0 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.24 KZN84392.1 - 6.2e-108 361.6 26.1 7.5e-108 361.3 26.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN84392.1 - 2.7e-20 72.6 35.8 1.8e-15 56.7 11.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Hydrophobin PF01185.18 KZN84393.1 - 0.0052 17.4 7.6 0.0085 16.7 7.6 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Granulin PF00396.18 KZN84393.1 - 0.051 13.9 2.9 0.051 13.9 2.9 2.4 3 0 0 3 3 3 0 Granulin GMC_oxred_N PF00732.19 KZN84394.1 - 7.1e-62 209.5 0.2 9.2e-62 209.1 0.2 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KZN84394.1 - 4.9e-34 117.9 0.0 8e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KZN84394.1 - 1.2e-05 25.4 0.3 3.7e-05 23.9 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KZN84394.1 - 9.5e-05 21.6 0.3 0.0052 15.9 0.4 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KZN84394.1 - 0.00012 21.3 0.1 0.00018 20.7 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KZN84394.1 - 0.00078 19.1 1.5 0.0016 18.1 0.6 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KZN84394.1 - 0.00092 18.5 0.4 0.0073 15.6 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KZN84394.1 - 0.0017 17.6 0.2 0.0062 15.8 0.1 1.8 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KZN84394.1 - 0.0042 15.8 0.1 0.0074 15.0 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KZN84394.1 - 0.011 16.3 1.5 0.026 15.1 0.5 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KZN84394.1 - 0.013 14.7 0.0 1.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KZN84394.1 - 0.1 12.9 0.1 0.22 11.8 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Rieske PF00355.26 KZN84395.1 - 7.3e-10 38.7 0.0 1.2e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KZN84395.1 - 3.5e-05 23.7 0.0 5.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain RNase_T PF00929.24 KZN84396.1 - 1.7e-07 31.9 0.0 1.7e-06 28.7 0.0 2.1 1 1 0 1 1 1 1 Exonuclease Glutaredoxin PF00462.24 KZN84397.1 - 4.9e-19 68.3 0.0 1.2e-17 63.8 0.0 2.4 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 KZN84397.1 - 1.1e-11 44.6 0.0 2.2e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KZN84397.1 - 0.00049 20.4 0.0 0.013 15.8 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like TauD PF02668.16 KZN84398.1 - 1.1e-48 166.4 0.5 1.8e-48 165.7 0.5 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KZN84398.1 - 3.2e-07 30.9 0.2 1e-06 29.3 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 KZN84398.1 - 0.00031 20.0 0.1 0.00098 18.3 0.1 1.8 1 1 0 1 1 1 1 CsiD Mito_carr PF00153.27 KZN84399.1 - 7.9e-63 208.4 1.8 1.6e-20 72.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 KZN84399.1 - 0.017 15.3 0.0 7.6 6.8 0.0 2.4 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Tubulin PF00091.25 KZN84400.1 - 5.5e-64 216.0 0.0 7.5e-64 215.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KZN84400.1 - 2.7e-45 153.6 0.0 4.1e-45 153.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KZN84400.1 - 0.019 14.7 0.0 0.057 13.1 0.0 1.7 1 1 0 1 1 1 0 Tubulin domain MS_channel PF00924.18 KZN84401.1 - 9.5e-26 90.6 2.5 2e-25 89.6 2.5 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 KZN84401.1 - 0.0003 20.1 0.0 0.00064 19.1 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 KZN84401.1 - 0.0014 18.0 0.3 0.0034 16.8 0.3 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KZN84401.1 - 0.0025 17.6 0.0 0.0069 16.2 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KZN84401.1 - 0.021 15.2 0.2 0.055 13.9 0.2 1.6 1 0 0 1 1 1 0 EF-hand domain pair Pkinase PF00069.25 KZN84402.1 - 1.2e-57 195.3 0.0 4.8e-39 134.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KZN84402.1 - 2.9e-26 92.3 0.0 2.8e-19 69.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 KZN84402.1 - 1.3e-12 47.9 0.0 2.4e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 KZN84402.1 - 1.1e-07 31.5 0.4 0.00013 21.4 0.0 2.7 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 KZN84402.1 - 1.6e-06 28.2 0.0 0.0042 17.0 0.2 2.9 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KZN84402.1 - 0.0059 16.0 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KZN84402.1 - 0.0087 15.0 0.0 0.02 13.9 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Tsc35 PF15079.6 KZN84402.1 - 0.043 13.4 0.0 0.086 12.4 0.0 1.4 1 0 0 1 1 1 0 Testis-specific protein 35 PAS_9 PF13426.7 KZN84402.1 - 0.082 13.2 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 PAS domain Seadorna_VP7 PF07387.11 KZN84402.1 - 0.11 11.6 0.1 0.2 10.6 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 KZN84402.1 - 0.13 11.8 0.0 21 4.6 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Fungal_trans PF04082.18 KZN84403.1 - 4.1e-23 81.8 0.1 6.5e-23 81.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN84403.1 - 2e-09 37.4 10.9 2e-09 37.4 10.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LCE6A PF15858.5 KZN84404.1 - 0.04 14.6 0.4 0.063 14.0 0.4 1.3 1 0 0 1 1 1 0 Late cornified envelope protein 6A family adh_short PF00106.25 KZN84406.1 - 5.3e-42 143.5 0.0 6.9e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN84406.1 - 3.1e-27 95.7 0.0 4e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN84406.1 - 1.8e-05 24.7 0.0 3.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KZN84406.1 - 0.0022 17.5 0.1 0.016 14.7 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KZN84406.1 - 0.0039 17.4 0.0 0.0057 16.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KZN84406.1 - 0.013 15.4 0.0 0.022 14.6 0.0 1.5 1 1 0 1 1 1 0 NAD(P)H-binding ABC2_membrane PF01061.24 KZN84407.1 - 8.1e-65 218.2 49.1 1.8e-35 122.3 20.4 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KZN84407.1 - 2.8e-40 138.0 0.0 1e-19 71.4 0.0 2.3 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KZN84407.1 - 3.4e-21 74.9 13.4 1.5e-18 66.4 0.2 3.3 4 0 0 4 4 3 2 CDR ABC transporter AAA_25 PF13481.6 KZN84407.1 - 3.7e-07 29.9 0.0 0.025 14.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KZN84407.1 - 3e-05 24.5 0.1 0.051 14.0 0.1 2.5 2 1 0 2 2 2 2 AAA ATPase domain ABC2_membrane_3 PF12698.7 KZN84407.1 - 3.9e-05 22.9 29.8 0.00042 19.5 11.5 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KZN84407.1 - 4.9e-05 23.3 0.3 0.0098 15.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KZN84407.1 - 7.8e-05 23.0 0.0 0.23 11.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KZN84407.1 - 0.00015 21.7 0.1 0.00089 19.2 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 KZN84407.1 - 0.00039 20.2 0.0 0.099 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KZN84407.1 - 0.00059 19.3 0.0 0.65 9.4 0.0 2.9 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 KZN84407.1 - 0.0013 18.7 0.5 1.1 9.2 0.1 2.5 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.6 KZN84407.1 - 0.0048 17.4 0.0 0.12 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KZN84407.1 - 0.0053 16.8 0.3 1.8 8.7 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KZN84407.1 - 0.0059 16.8 0.7 2 8.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KZN84407.1 - 0.0069 16.1 0.2 0.68 9.7 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.19 KZN84407.1 - 0.012 15.3 1.7 1.1 8.9 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 KZN84407.1 - 0.019 14.2 0.0 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Septin P5-ATPase PF12409.8 KZN84407.1 - 0.024 14.7 1.3 0.05 13.7 0.6 1.9 2 0 0 2 2 1 0 P5-type ATPase cation transporter T2SSE PF00437.20 KZN84407.1 - 0.028 13.5 0.0 3 6.8 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein PduV-EutP PF10662.9 KZN84407.1 - 0.037 13.8 1.9 2.9 7.6 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 KZN84407.1 - 0.044 13.8 0.8 1.6 8.7 0.3 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KZN84407.1 - 0.073 12.8 0.1 5.3 6.7 0.0 2.9 4 0 0 4 4 3 0 AAA domain Pox_A32 PF04665.12 KZN84407.1 - 0.11 11.9 0.7 2.7 7.4 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_15 PF13175.6 KZN84407.1 - 0.13 12.0 0.0 2.8 7.6 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain AAA PF00004.29 KZN84407.1 - 0.13 12.7 0.5 9.7 6.6 0.1 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KZN84407.1 - 0.16 12.4 0.6 1.3 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KZN84407.1 - 0.44 10.3 1.1 21 4.8 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 KZN84407.1 - 0.53 10.6 1.5 9.3 6.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KZN84407.1 - 1.4 8.5 3.9 3.4 7.3 0.8 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Oxidored_FMN PF00724.20 KZN84408.1 - 1.2e-75 254.9 0.0 1.6e-75 254.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Sugar_tr PF00083.24 KZN84409.1 - 2.6e-108 362.8 22.7 2.9e-108 362.6 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN84409.1 - 9.4e-24 84.0 26.4 5e-21 75.0 16.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3188 PF11384.8 KZN84409.1 - 0.047 13.4 3.5 26 4.6 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3188) Phe_tRNA-synt_N PF02912.18 KZN84409.1 - 0.074 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain Peptidase_M48 PF01435.18 KZN84409.1 - 0.12 12.2 0.2 0.28 10.9 0.2 1.6 1 0 0 1 1 1 0 Peptidase family M48 DUF996 PF06195.13 KZN84409.1 - 8.7 6.6 12.8 0.27 11.5 0.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF996) Hexapep PF00132.24 KZN84410.1 - 3.5e-14 51.9 11.1 2.1e-11 43.0 1.2 4.1 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KZN84410.1 - 5.6e-14 51.6 9.8 1.7e-10 40.5 0.8 2.8 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 KZN84410.1 - 7.6e-12 45.3 0.0 1.4e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase MFS_1 PF07690.16 KZN84411.1 - 3.3e-39 134.8 46.7 7.7e-39 133.6 28.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MWFE PF15879.5 KZN84411.1 - 0.01 16.0 0.2 0.13 12.4 0.1 2.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit AOX PF01786.17 KZN84411.1 - 0.093 12.3 1.3 3.4 7.2 0.0 2.5 3 0 0 3 3 3 0 Alternative oxidase MFS_1 PF07690.16 KZN84412.1 - 8.1e-31 107.2 37.5 2.4e-27 95.8 38.4 3.3 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4514 PF14986.6 KZN84412.1 - 0.13 12.2 0.1 0.41 10.7 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) MFS_1 PF07690.16 KZN84413.1 - 7.9e-06 25.0 1.5 9.2e-06 24.8 1.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KZN84414.1 - 1.3e-22 80.2 22.9 1.3e-22 80.2 22.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Pro_racemase PF05544.11 KZN84415.1 - 1.7e-61 208.1 0.0 2.2e-61 207.7 0.0 1.2 1 0 0 1 1 1 1 Proline racemase Peptidase_M24 PF00557.24 KZN84416.1 - 2e-42 145.2 0.0 2.7e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KZN84416.1 - 4.3e-22 78.1 6.2 7.8e-22 77.3 6.2 1.4 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KZN84416.1 - 0.00086 19.4 5.6 0.0019 18.3 5.6 1.6 1 0 0 1 1 1 1 MYND finger 3Beta_HSD PF01073.19 KZN84417.1 - 3.6e-44 150.9 0.0 7.4e-40 136.7 0.0 2.0 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KZN84417.1 - 9.7e-19 67.8 0.3 4.9e-16 58.9 0.0 2.5 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KZN84417.1 - 1.7e-13 50.7 0.1 6.9e-11 42.1 0.0 2.9 3 1 0 3 3 3 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KZN84417.1 - 2.3e-10 40.1 0.0 5.6e-08 32.3 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KZN84417.1 - 1.4e-05 24.4 0.0 3.8e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KZN84417.1 - 0.08 12.1 0.0 0.39 9.8 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Fmp27_WPPW PF10359.9 KZN84418.1 - 0.059 12.2 0.0 0.074 11.9 0.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain UQ_con PF00179.26 KZN84419.1 - 2.8e-06 27.1 0.1 7e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Kdo PF06293.14 KZN84420.1 - 0.001 18.5 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KZN84420.1 - 0.0011 19.0 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KZN84420.1 - 0.0013 18.2 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RhoGAP PF00620.27 KZN84421.1 - 4.1e-35 120.9 0.3 7.5e-35 120.0 0.3 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KZN84421.1 - 5e-25 87.5 43.0 5.3e-11 42.6 6.0 4.8 5 0 0 5 5 5 4 LIM domain DUF1272 PF06906.11 KZN84421.1 - 0.0061 16.6 0.1 0.0061 16.6 0.1 4.0 3 1 1 4 4 4 1 Protein of unknown function (DUF1272) T2SSE PF00437.20 KZN84421.1 - 0.03 13.4 0.1 0.048 12.7 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Desulfoferrod_N PF06397.12 KZN84421.1 - 0.47 10.1 2.4 0.46 10.1 0.3 2.1 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain zinc_ribbon_12 PF11331.8 KZN84421.1 - 1.2 9.0 9.5 0.29 11.0 0.1 3.5 3 0 0 3 3 3 0 Probable zinc-ribbon domain MFS_1 PF07690.16 KZN84422.1 - 7.1e-27 94.2 46.0 6.1e-25 87.9 36.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KZN84422.1 - 4.2e-05 22.2 3.3 4.2e-05 22.2 3.3 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) NAD_binding_4 PF07993.12 KZN84423.1 - 5.8e-35 120.7 0.3 2.2e-32 112.2 0.3 3.0 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KZN84423.1 - 1.3e-05 24.8 0.0 2.3e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KZN84424.1 - 0.0002 21.3 0.0 0.00027 20.9 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AA_permease_2 PF13520.6 KZN84425.1 - 5.3e-47 160.6 44.1 1.1e-24 87.1 13.8 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 KZN84425.1 - 1.7e-11 43.4 37.0 5.6e-06 25.2 15.2 2.5 1 1 1 2 2 2 2 Amino acid permease Fungal_trans_2 PF11951.8 KZN84426.1 - 5.6e-37 127.5 2.5 7.2e-37 127.1 2.5 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nbl1_Borealin_N PF10444.9 KZN84427.1 - 2.1e-18 65.7 3.6 2.1e-18 65.7 3.6 1.8 2 0 0 2 2 2 1 Nbl1 / Borealin N terminal VWA_2 PF13519.6 KZN84428.1 - 1.5e-20 73.8 0.3 5.2e-20 72.1 0.1 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 KZN84428.1 - 1.6e-05 24.8 0.1 2.3e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.28 KZN84428.1 - 0.00012 22.4 0.6 0.00018 21.8 0.6 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.20 KZN84428.1 - 0.047 13.6 0.1 0.18 11.8 0.1 2.1 1 0 0 1 1 1 0 Ubiquitin interaction motif PDH PF02153.17 KZN84428.1 - 0.055 12.5 0.1 0.083 11.9 0.1 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase Sybindin PF04099.12 KZN84429.1 - 1.2e-46 158.2 0.0 2.5e-46 157.1 0.0 1.5 1 1 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KZN84429.1 - 3.2e-07 30.5 0.0 5.1e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region ABC2_membrane PF01061.24 KZN84430.1 - 3.5e-79 265.1 64.6 1.5e-44 151.9 26.4 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KZN84430.1 - 6e-36 124.0 0.0 1.9e-16 60.8 0.0 3.4 4 0 0 4 4 4 2 ABC transporter PDR_CDR PF06422.12 KZN84430.1 - 6.3e-30 102.9 13.3 3.9e-29 100.4 0.0 4.0 4 0 0 4 4 4 2 CDR ABC transporter ABC_trans_N PF14510.6 KZN84430.1 - 6.3e-19 68.4 0.1 1.4e-18 67.3 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 KZN84430.1 - 0.00053 19.9 0.1 0.024 14.6 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KZN84430.1 - 0.0013 18.4 0.6 0.0053 16.4 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KZN84430.1 - 0.0014 19.2 0.1 0.014 15.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KZN84430.1 - 0.0028 17.5 0.0 4.8 6.9 0.0 3.1 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KZN84430.1 - 0.0037 17.6 0.1 0.38 11.1 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 KZN84430.1 - 0.005 16.6 0.1 0.091 12.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KZN84430.1 - 0.01 16.0 0.1 0.78 9.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KZN84430.1 - 0.016 14.6 0.0 1.7 8.0 0.0 2.9 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KZN84430.1 - 0.023 14.4 1.2 1.2 9.0 0.2 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.12 KZN84430.1 - 0.039 13.9 1.2 18 5.2 0.0 3.3 3 0 0 3 3 3 0 NACHT domain AAA_30 PF13604.6 KZN84430.1 - 0.099 12.3 0.2 11 5.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KZN84430.1 - 0.1 12.9 0.1 8.8 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KZN84430.1 - 0.19 11.8 0.1 34 4.6 0.1 3.0 3 0 0 3 3 3 0 50S ribosome-binding GTPase cobW PF02492.19 KZN84430.1 - 0.36 10.4 0.8 2.2 7.8 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2678 PF10856.8 KZN84430.1 - 1.5 8.8 5.6 0.7 9.8 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2678) ABC2_membrane_3 PF12698.7 KZN84430.1 - 1.6 7.8 46.9 0.04 13.0 20.5 2.7 2 1 0 2 2 2 0 ABC-2 family transporter protein Arylsulfotran_2 PF14269.6 KZN84431.1 - 8.6e-75 251.9 0.4 1.3e-74 251.3 0.4 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KZN84431.1 - 6.6e-15 54.9 0.0 3.3e-13 49.3 0.0 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Ectoine_synth PF06339.12 KZN84431.1 - 0.22 11.7 1.0 19 5.4 0.1 2.3 2 0 0 2 2 2 0 Ectoine synthase MFS_1 PF07690.16 KZN84432.1 - 2.3e-42 145.2 43.6 2.3e-42 145.2 43.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN84432.1 - 7.5e-12 44.8 17.3 7.5e-12 44.8 17.3 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter Alpha-L-AF_C PF06964.12 KZN84433.1 - 1e-23 84.3 0.1 2.3e-23 83.1 0.1 1.6 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Gmad2 PF10648.9 KZN84433.1 - 0.034 14.4 0.1 0.17 12.2 0.1 2.3 2 0 0 2 2 2 0 Immunoglobulin-like domain of bacterial spore germination PA_decarbox PF05870.11 KZN84434.1 - 3.2e-09 36.6 0.0 3.8e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) Bac_rhamnosid6H PF17389.2 KZN84435.1 - 7.7e-17 61.6 1.3 6.9e-16 58.4 1.3 2.0 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KZN84435.1 - 6.3e-08 32.3 0.0 4.3e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Trehalase PF01204.18 KZN84435.1 - 1.5e-05 24.0 0.9 2.2e-05 23.5 0.9 1.1 1 0 0 1 1 1 1 Trehalase Glyco_hydro_36 PF17167.4 KZN84435.1 - 0.011 14.5 0.8 0.018 13.7 0.8 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain Bac_rhamnosid PF05592.11 KZN84435.1 - 0.15 12.0 0.0 0.83 9.7 0.0 2.1 1 1 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain TPR_12 PF13424.6 KZN84436.1 - 3.4e-30 104.1 0.0 6.4e-10 39.2 0.0 4.6 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 KZN84436.1 - 8.5e-30 101.8 0.0 5.9e-07 29.1 0.0 7.0 6 0 0 6 6 6 5 Tetratricopeptide repeat Patatin PF01734.22 KZN84436.1 - 3.3e-18 66.6 0.1 1.1e-17 64.9 0.0 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase NB-ARC PF00931.22 KZN84436.1 - 1.3e-13 50.8 0.1 2.6e-13 49.8 0.1 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_2 PF07719.17 KZN84436.1 - 1.3e-11 43.6 0.1 0.23 11.7 0.0 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KZN84436.1 - 5.4e-11 42.5 0.1 3.6e-07 29.9 0.0 2.6 1 1 1 2 2 2 2 MalT-like TPR region TPR_8 PF13181.6 KZN84436.1 - 1.1e-08 34.6 0.5 1.3 9.4 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KZN84436.1 - 6.1e-08 32.2 2.3 0.43 10.7 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KZN84436.1 - 2.9e-07 30.0 0.2 0.36 10.7 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KZN84436.1 - 6.1e-07 29.8 0.0 0.22 12.1 0.0 4.3 3 1 1 4 4 3 2 Tetratricopeptide repeat NACHT PF05729.12 KZN84436.1 - 3.6e-06 27.0 0.0 8.1e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Coatomer_E PF04733.14 KZN84436.1 - 8.3e-05 22.1 0.7 0.023 14.1 0.0 3.1 3 1 0 3 3 3 1 Coatomer epsilon subunit AAA_22 PF13401.6 KZN84436.1 - 0.00031 21.0 0.1 0.002 18.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain TPR_14 PF13428.6 KZN84436.1 - 0.00066 20.3 0.3 10 7.2 0.1 5.4 4 2 2 6 6 5 0 Tetratricopeptide repeat IstB_IS21 PF01695.17 KZN84436.1 - 0.0012 18.6 0.0 0.0039 16.9 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF3856 PF12968.7 KZN84436.1 - 0.018 15.1 0.0 0.84 9.7 0.0 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) Mltc_N PF11873.8 KZN84436.1 - 0.051 13.3 0.0 6.5 6.5 0.0 3.0 3 0 0 3 3 3 0 Membrane-bound lytic murein transglycosylase C, N-terminal domain TPR_16 PF13432.6 KZN84436.1 - 0.065 13.9 0.0 11 6.8 0.0 3.8 4 1 1 5 5 3 0 Tetratricopeptide repeat Pex14_N PF04695.13 KZN84437.1 - 1.8 9.2 10.0 2.6 8.7 10.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SH3BGR PF04908.15 KZN84439.1 - 0.00042 20.4 0.0 0.0017 18.5 0.0 2.1 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Carboxyl_trans PF01039.22 KZN84439.1 - 0.041 12.5 0.1 0.066 11.8 0.1 1.4 1 0 0 1 1 1 0 Carboxyl transferase domain Ribul_P_3_epim PF00834.19 KZN84440.1 - 2.7e-60 203.2 0.0 4e-59 199.3 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.24 KZN84440.1 - 0.12 12.0 0.1 0.21 11.1 0.0 1.5 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Methyltransf_11 PF08241.12 KZN84441.1 - 4.4e-08 33.7 0.0 9.2e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN84441.1 - 0.0011 19.6 0.0 0.0029 18.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN84441.1 - 0.053 13.4 0.0 0.14 11.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain LSM PF01423.22 KZN84442.1 - 3.9e-17 61.7 0.6 5e-17 61.4 0.6 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KZN84442.1 - 0.013 15.6 0.0 0.017 15.2 0.0 1.3 1 1 0 1 1 1 0 Ataxin 2 SM domain Hfq PF17209.3 KZN84442.1 - 0.019 14.6 0.1 0.029 14.0 0.1 1.3 1 0 0 1 1 1 0 Hfq protein LRR_9 PF14580.6 KZN84442.1 - 0.04 13.4 0.1 0.048 13.2 0.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeat NTP_transf_2 PF01909.23 KZN84442.1 - 0.1 12.9 0.0 0.2 11.9 0.0 1.5 1 1 0 1 1 1 0 Nucleotidyltransferase domain DRMBL PF07522.14 KZN84443.1 - 6.8e-34 116.4 0.0 1.3e-33 115.5 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KZN84443.1 - 0.00033 20.2 0.0 0.00072 19.1 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TIP49 PF06068.13 KZN84443.1 - 0.28 10.4 0.2 0.44 9.7 0.2 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Abhydrolase_6 PF12697.7 KZN84444.1 - 2.4e-10 41.4 0.0 4.5e-10 40.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KZN84444.1 - 2.2e-07 30.8 0.1 3.5e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KZN84444.1 - 8.3e-06 25.2 0.1 1.4e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 p450 PF00067.22 KZN84445.1 - 8e-102 341.4 0.0 9.7e-102 341.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 OPT PF03169.15 KZN84446.1 - 1.6e-181 605.1 58.3 1.9e-181 604.9 58.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Zn_clus PF00172.18 KZN84447.1 - 7.6e-07 29.1 7.5 7.6e-07 29.1 7.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gag_p10 PF02337.17 KZN84447.1 - 0.1 12.5 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 Retroviral GAG p10 protein SMP PF04927.12 KZN84448.1 - 7.3e-14 52.0 15.6 0.00018 21.9 1.9 3.2 2 1 1 3 3 3 3 Seed maturation protein GFA PF04828.14 KZN84449.1 - 4.9e-25 87.7 0.0 7.4e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NMD3 PF04981.13 KZN84449.1 - 0.11 11.9 0.5 0.42 10.0 0.3 1.8 2 0 0 2 2 2 0 NMD3 family DZR PF12773.7 KZN84449.1 - 0.14 12.2 4.0 0.85 9.7 0.3 2.5 2 1 0 2 2 2 0 Double zinc ribbon Citrate_synt PF00285.21 KZN84450.1 - 9.4e-70 235.5 0.0 1.1e-69 235.2 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain MFS_1 PF07690.16 KZN84451.1 - 7.8e-44 150.0 28.6 1.3e-43 149.3 28.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily PBP PF01161.20 KZN84451.1 - 2.1e-12 47.5 0.1 3.5e-12 46.8 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Sugar_tr PF00083.24 KZN84451.1 - 5.9e-07 28.7 8.4 5.9e-07 28.7 8.4 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KZN84451.1 - 6.2e-05 21.6 3.9 6.2e-05 21.6 3.9 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KZN84451.1 - 0.0032 15.9 5.2 0.0032 15.9 5.2 1.6 2 0 0 2 2 2 1 Transmembrane secretion effector DUF4079 PF13301.6 KZN84451.1 - 0.041 14.0 0.0 0.38 10.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) Zn_clus PF00172.18 KZN84452.1 - 2.7e-08 33.8 5.6 6.2e-08 32.6 5.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PBP PF01161.20 KZN84453.1 - 6.4e-21 75.0 0.0 7.5e-21 74.8 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Epimerase PF01370.21 KZN84454.1 - 2e-07 30.7 0.4 1.9e-06 27.5 0.4 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KZN84454.1 - 8.6e-07 29.0 0.1 1.2e-06 28.6 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KZN84454.1 - 1.7e-06 27.8 0.1 6.5e-06 25.9 0.2 1.8 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 KZN84454.1 - 0.00028 20.0 0.2 0.0033 16.5 0.1 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 KZN84454.1 - 0.044 14.0 0.3 0.087 13.1 0.3 1.6 1 0 0 1 1 1 0 TrkA-N domain ATG22 PF11700.8 KZN84455.1 - 9.3e-188 624.7 8.2 1.1e-187 624.5 8.2 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like TMEM252 PF15664.5 KZN84455.1 - 0.039 13.7 0.1 0.071 12.8 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 252 family MFS_1 PF07690.16 KZN84455.1 - 0.085 11.8 55.4 0.026 13.5 20.7 3.5 2 1 1 3 3 3 0 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN84459.1 - 3.9e-78 263.3 28.4 4.6e-78 263.1 28.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN84459.1 - 9.5e-20 70.8 38.4 1.1e-17 64.0 29.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HrpB1_HrpK PF09613.10 KZN84459.1 - 0.17 11.6 0.6 1 9.0 0.2 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) F-box-like PF12937.7 KZN84460.1 - 0.025 14.4 0.4 0.075 12.9 0.1 2.0 2 0 0 2 2 2 0 F-box-like Dioxygenase_C PF00775.21 KZN84462.1 - 1.6e-09 37.5 0.1 2.5e-09 36.8 0.1 1.2 1 0 0 1 1 1 1 Dioxygenase MFS_1 PF07690.16 KZN84463.1 - 1e-25 90.4 32.5 1e-25 90.4 32.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN84463.1 - 2.1e-09 36.8 8.1 2.1e-09 36.8 8.1 2.1 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KZN84463.1 - 9.4e-06 24.3 1.9 1.6e-05 23.5 1.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) adh_short_C2 PF13561.6 KZN84464.1 - 2.8e-63 213.6 0.1 3.2e-63 213.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN84464.1 - 1.1e-42 145.8 0.1 1.3e-42 145.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN84464.1 - 1.1e-16 61.3 0.1 1.5e-16 60.8 0.1 1.1 1 0 0 1 1 1 1 KR domain SRF-TF PF00319.18 KZN84464.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) GH131_N PF18271.1 KZN84465.1 - 4.5e-64 216.6 1.1 5e-64 216.4 1.1 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Sugar_tr PF00083.24 KZN84466.1 - 1e-97 327.9 27.2 1.2e-97 327.7 27.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN84466.1 - 3.4e-23 82.1 27.5 3.4e-23 82.1 27.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KZN84466.1 - 1.9e-05 23.3 1.5 1.9e-05 23.3 1.5 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KZN84467.1 - 3.3e-45 154.6 36.2 4.2e-45 154.2 36.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN84467.1 - 9.2e-18 64.3 15.5 2.8e-17 62.7 15.4 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 KZN84467.1 - 0.29 9.4 16.8 0.0041 15.5 6.1 2.6 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Pam17 PF08566.10 KZN84467.1 - 0.44 10.4 2.2 0.61 9.9 0.1 2.0 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 Aa_trans PF01490.18 KZN84468.1 - 7.6e-40 136.9 35.1 9.1e-40 136.6 35.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 KZN84469.1 - 1.2e-48 166.0 45.0 1.6e-48 165.7 45.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN84469.1 - 5.1e-23 81.4 37.9 6.8e-23 81.0 37.9 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1275 PF06912.11 KZN84471.1 - 4e-43 147.6 17.8 4.6e-43 147.4 17.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Tmemb_185A PF10269.9 KZN84471.1 - 0.012 15.3 0.7 0.018 14.7 0.7 1.3 1 0 0 1 1 1 0 Transmembrane Fragile-X-F protein Cupin_1 PF00190.22 KZN84472.1 - 8.3e-40 135.8 0.0 1.1e-18 67.3 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KZN84472.1 - 4.9e-25 87.0 0.8 2.4e-11 43.2 0.1 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KZN84472.1 - 3.6e-09 36.2 0.0 5.4e-05 22.8 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KZN84472.1 - 1.6e-06 28.1 0.2 0.00068 19.5 0.1 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Glyco_hydro_31 PF01055.26 KZN84476.1 - 6.6e-42 144.2 8.8 9.2e-42 143.7 8.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KZN84476.1 - 0.03 14.7 0.1 0.13 12.6 0.0 2.2 2 0 0 2 2 2 0 Galactose mutarotase-like AA_permease_2 PF13520.6 KZN84477.1 - 4.3e-77 259.7 38.6 5.3e-77 259.4 38.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN84477.1 - 1.6e-19 69.9 34.9 2.1e-19 69.5 34.9 1.1 1 0 0 1 1 1 1 Amino acid permease Ni_hydr_CYTB PF01292.20 KZN84477.1 - 6.1 6.4 17.4 0.1 12.2 2.5 3.9 2 2 2 4 4 4 0 Prokaryotic cytochrome b561 Glyco_hydro_92 PF07971.12 KZN84478.1 - 3e-136 455.0 8.0 4.1e-136 454.6 8.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KZN84478.1 - 6e-62 209.7 2.5 1.2e-61 208.6 2.5 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain UPRTase PF14681.6 KZN84479.1 - 5.7e-41 140.2 0.1 1.1e-40 139.3 0.1 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.6 KZN84479.1 - 1.5e-17 64.3 0.0 3.3e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain HAD PF12710.7 KZN84479.1 - 6.8e-17 62.5 0.1 1.3e-16 61.5 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pribosyltran PF00156.27 KZN84479.1 - 0.00062 19.3 0.5 0.004 16.7 0.5 2.2 1 1 0 1 1 1 1 Phosphoribosyl transferase domain AAA_18 PF13238.6 KZN84479.1 - 0.0065 17.0 0.0 0.014 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain PRTase_2 PF15609.6 KZN84479.1 - 0.0073 15.8 0.2 0.02 14.4 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase AAA_16 PF13191.6 KZN84479.1 - 0.0083 16.5 0.0 0.16 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain KAP_NTPase PF07693.14 KZN84479.1 - 0.019 14.2 0.0 0.041 13.1 0.0 1.6 2 0 0 2 2 2 0 KAP family P-loop domain AAA_22 PF13401.6 KZN84479.1 - 0.029 14.6 0.0 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain Peptidase_U4 PF03419.13 KZN84479.1 - 0.046 13.0 0.0 0.076 12.3 0.0 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Hydrolase_3 PF08282.12 KZN84479.1 - 0.05 13.3 0.1 0.37 10.5 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Zeta_toxin PF06414.12 KZN84479.1 - 0.072 12.4 0.0 0.3 10.3 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin Peptidase_M50B PF13398.6 KZN84481.1 - 5.6e-60 202.4 22.2 6.7e-60 202.1 22.2 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.22 KZN84481.1 - 0.008 15.5 0.4 0.016 14.5 0.4 1.5 1 0 0 1 1 1 1 Peptidase family M50 Peptidase_M41 PF01434.18 KZN84481.1 - 0.21 11.4 0.1 0.35 10.7 0.1 1.3 1 0 0 1 1 1 0 Peptidase family M41 Patched PF02460.18 KZN84481.1 - 3.3 5.6 7.0 5 5.1 7.0 1.2 1 0 0 1 1 1 0 Patched family DUF2703 PF10865.8 KZN84482.1 - 0.0092 16.2 0.5 0.72 10.0 0.2 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF2703) SlyX PF04102.12 KZN84482.1 - 0.15 12.7 3.0 0.43 11.2 0.0 3.1 3 0 0 3 3 3 0 SlyX Beta_elim_lyase PF01212.21 KZN84483.1 - 2.6e-68 230.5 0.0 3e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 KZN84483.1 - 0.00047 19.0 0.0 0.00091 18.1 0.0 1.3 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.20 KZN84483.1 - 0.0051 15.4 0.0 0.0081 14.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pkinase PF00069.25 KZN84484.1 - 1e-68 231.6 0.0 2.2e-68 230.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN84484.1 - 1.7e-33 116.0 0.0 2.6e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KZN84484.1 - 1.2e-10 41.5 0.4 3.6e-10 40.0 0.4 1.8 2 0 0 2 2 2 1 FHA domain APH PF01636.23 KZN84484.1 - 1.3e-05 25.2 0.8 0.019 14.9 0.1 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Yop-YscD_cpl PF16697.5 KZN84484.1 - 0.00016 21.9 0.1 0.00036 20.8 0.1 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 KZN84484.1 - 0.00017 21.0 0.3 0.00034 20.0 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KZN84484.1 - 0.002 17.5 0.0 0.006 15.9 0.0 1.7 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KZN84484.1 - 0.032 13.8 0.1 0.059 13.0 0.1 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KZN84484.1 - 0.049 12.4 0.0 0.089 11.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KZN84484.1 - 0.089 12.4 0.3 0.15 11.7 0.3 1.3 1 0 0 1 1 1 0 RIO1 family CaMBD PF02888.16 KZN84484.1 - 0.15 12.3 0.3 0.34 11.1 0.3 1.5 1 0 0 1 1 1 0 Calmodulin binding domain Glyco_transf_34 PF05637.12 KZN84485.1 - 4e-62 210.1 0.5 5.3e-62 209.6 0.5 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family NDUFB10 PF10249.9 KZN84486.1 - 0.007 16.9 0.0 0.0077 16.7 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 ANAPC9 PF12856.7 KZN84486.1 - 0.19 11.9 0.0 13 6.0 0.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 9 BRO1 PF03097.18 KZN84487.1 - 1.2e-08 34.2 0.0 1.8e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain Glyco_hydro_16 PF00722.21 KZN84489.1 - 2.4e-23 82.5 0.9 3e-14 52.9 0.3 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.21 KZN84490.1 - 1.8e-37 128.5 4.2 2.9e-37 127.9 4.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF347 PF03988.12 KZN84490.1 - 0.041 14.1 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Bromo_TP PF07524.13 KZN84491.1 - 1.7e-06 27.9 0.0 3.1e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated AstB PF04996.12 KZN84491.1 - 0.011 14.4 0.0 0.015 14.0 0.0 1.1 1 0 0 1 1 1 0 Succinylarginine dihydrolase TFIID-31kDa PF02291.15 KZN84491.1 - 0.027 14.5 0.0 0.045 13.8 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TAFII55_N PF04658.13 KZN84492.1 - 1.3e-49 168.0 0.0 1.3e-49 168.0 0.0 2.3 3 0 0 3 3 3 1 TAFII55 protein conserved region DUF4407 PF14362.6 KZN84492.1 - 0.87 8.9 6.4 1.4 8.2 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RPA43_OB PF17875.1 KZN84492.1 - 9.5 6.9 12.8 5.4 7.6 1.4 2.6 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I Epimerase PF01370.21 KZN84494.1 - 2.2e-12 46.9 0.0 3.5e-12 46.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KZN84494.1 - 2.9e-11 42.9 0.0 4e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KZN84494.1 - 4.4e-09 36.5 0.0 6.8e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KZN84494.1 - 5.4e-09 35.6 0.0 3.2e-05 23.2 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KZN84494.1 - 3.2e-07 30.1 0.0 5.2e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KZN84494.1 - 0.00011 21.8 0.0 0.00053 19.6 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 KZN84494.1 - 0.00075 18.7 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KZN84494.1 - 0.026 13.6 0.0 0.098 11.7 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain DapB_N PF01113.20 KZN84494.1 - 0.2 11.8 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.26 KZN84495.1 - 3.2e-23 82.1 0.1 6.6e-23 81.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KZN84495.1 - 1e-21 76.8 0.8 2.2e-21 75.8 0.4 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KZN84495.1 - 5.1e-05 24.3 0.0 0.00011 23.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MinC_N PF05209.13 KZN84495.1 - 0.0045 16.9 0.0 0.015 15.2 0.0 1.8 2 0 0 2 2 2 1 Septum formation inhibitor MinC, N-terminal domain EthD PF07110.11 KZN84496.1 - 8.5e-12 46.1 0.4 1.3e-11 45.5 0.4 1.3 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KZN84496.1 - 0.1 13.1 0.2 0.16 12.4 0.2 1.3 1 1 0 1 1 1 0 Methylmuconolactone methyl-isomerase ECH_1 PF00378.20 KZN84497.1 - 1.4e-21 77.0 0.0 1.5e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KZN84497.1 - 1.1e-05 25.1 0.0 1.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KZN84497.1 - 0.025 14.6 0.0 6.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 DUF3880 PF12996.7 KZN84498.1 - 0.043 13.9 0.0 0.066 13.3 0.0 1.3 1 0 0 1 1 1 0 DUF based on E. rectale Gene description (DUF3880) DUF4291 PF14124.6 KZN84500.1 - 1.7e-74 249.6 0.0 1.9e-74 249.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Ofd1_CTDD PF10637.9 KZN84502.1 - 4.1e-98 327.8 0.1 8.2e-94 313.7 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KZN84502.1 - 7.6e-26 90.6 0.0 1.8e-25 89.5 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KZN84502.1 - 4.8e-14 53.0 0.0 9.5e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CitMHS PF03600.16 KZN84503.1 - 0.39 9.9 2.5 0.51 9.5 2.5 1.1 1 0 0 1 1 1 0 Citrate transporter HLH PF00010.26 KZN84504.1 - 1.4e-14 53.8 0.2 4.5e-14 52.1 0.2 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Flagellin_N PF00669.20 KZN84504.1 - 0.36 10.9 4.0 0.92 9.6 0.2 2.3 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region DUF4587 PF15248.6 KZN84504.1 - 1.6 9.6 11.1 2.9 8.7 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4587) Phosphodiest PF01663.22 KZN84507.1 - 1.8e-91 307.5 0.2 2.2e-91 307.1 0.2 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KZN84507.1 - 0.00022 20.8 0.1 0.23 10.8 0.0 2.2 2 0 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.18 KZN84507.1 - 0.017 14.5 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily AP_endonuc_2 PF01261.24 KZN84507.1 - 0.057 12.9 0.0 0.95 8.9 0.0 2.2 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel WD40 PF00400.32 KZN84508.1 - 6.6e-56 185.0 21.3 7.1e-11 42.5 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat Pkinase PF00069.25 KZN84508.1 - 2.7e-34 118.7 0.0 3.6e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain ANAPC4_WD40 PF12894.7 KZN84508.1 - 3.4e-22 78.6 0.2 0.00024 21.3 0.0 6.2 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Pkinase_Tyr PF07714.17 KZN84508.1 - 4.4e-19 68.8 0.0 6.5e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ge1_WD40 PF16529.5 KZN84508.1 - 2.4e-13 49.8 0.6 0.031 13.2 0.1 5.6 1 1 4 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 KZN84508.1 - 3e-13 49.2 1.0 1 9.1 0.0 6.8 7 0 0 7 7 7 4 Proteasome subunit A N-terminal signature PD40 PF07676.12 KZN84508.1 - 1.5e-10 40.7 1.0 2.6 8.1 0.0 7.3 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KZN84508.1 - 5e-09 36.3 0.1 0.015 15.2 0.0 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KZN84508.1 - 1.7e-07 30.1 0.0 0.059 11.9 0.0 3.5 1 1 0 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.8 KZN84508.1 - 1.1e-05 24.3 3.2 0.094 11.3 0.1 4.6 2 2 3 5 5 5 2 Nucleoporin Nup120/160 DUF1513 PF07433.11 KZN84508.1 - 1.4e-05 24.3 2.1 0.075 12.1 0.1 3.6 2 2 1 4 4 4 2 Protein of unknown function (DUF1513) TruB_C PF09142.11 KZN84508.1 - 1.9e-05 24.3 0.1 44 3.9 0.0 5.9 6 0 0 6 6 6 0 tRNA Pseudouridine synthase II, C terminal WD40_like PF17005.5 KZN84508.1 - 0.003 17.0 0.0 12 5.2 0.0 3.1 3 0 0 3 3 3 0 WD40-like domain DUF5122 PF17164.4 KZN84508.1 - 0.0042 17.3 1.6 1.4e+02 2.9 0.0 5.9 7 0 0 7 7 6 0 Domain of unknown function (DUF5122) beta-propeller SoxG PF04268.12 KZN84508.1 - 0.0058 16.8 0.2 0.89 9.7 0.0 3.0 1 1 1 2 2 2 1 Sarcosine oxidase, gamma subunit family IKI3 PF04762.12 KZN84508.1 - 0.0059 14.7 0.0 2.7 5.8 0.0 3.0 2 1 0 2 2 2 2 IKI3 family Kdo PF06293.14 KZN84508.1 - 0.009 15.4 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CN_hydrolase PF00795.22 KZN84508.1 - 0.049 13.0 0.2 10 5.3 0.0 3.9 3 2 1 4 4 4 0 Carbon-nitrogen hydrolase Ntox33 PF15533.6 KZN84508.1 - 0.21 12.1 0.1 28 5.3 0.0 3.0 3 0 0 3 3 3 0 Bacterial toxin 33 DUF5570 PF17731.1 KZN84508.1 - 0.7 10.0 5.9 41 4.3 0.0 4.4 1 1 4 5 5 5 0 Family of unknown function (DUF5570) BCS1_N PF08740.11 KZN84510.1 - 1.4e-47 162.1 1.5 2.3e-47 161.4 1.5 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KZN84510.1 - 2.5e-18 66.8 0.0 4.2e-08 33.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KZN84510.1 - 0.0052 17.2 0.2 0.013 15.9 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KZN84510.1 - 0.03 13.9 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KZN84510.1 - 0.035 13.5 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.6 KZN84510.1 - 0.036 14.6 0.2 0.12 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KZN84510.1 - 0.12 12.4 0.0 0.56 10.2 0.0 2.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 KZN84510.1 - 0.17 11.7 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KZN84510.1 - 0.21 11.9 0.4 0.97 9.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain Glyco_hydro_43 PF04616.14 KZN84511.1 - 1.2e-33 116.7 0.0 1.6e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KZN84511.1 - 0.23 11.0 1.7 0.34 10.4 0.2 2.0 2 1 0 2 2 2 0 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_31 PF01055.26 KZN84512.1 - 4.7e-92 309.5 10.6 6.1e-92 309.1 10.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF3533 PF12051.8 KZN84513.1 - 2.3e-98 329.6 10.7 2.8e-98 329.3 10.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Pkinase PF00069.25 KZN84514.1 - 8.5e-08 31.9 0.0 2.4e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN84514.1 - 0.047 13.0 0.0 0.12 11.6 0.0 1.7 1 1 1 2 2 2 0 Protein tyrosine kinase Pkinase PF00069.25 KZN84515.1 - 4.2e-12 46.0 0.0 2.1e-11 43.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN84515.1 - 2.3e-05 23.8 0.0 0.00068 19.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KZN84515.1 - 0.0019 17.6 0.0 0.0032 16.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Nuc_rec_co-act PF08815.10 KZN84515.1 - 0.19 11.6 0.1 4.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Nuclear receptor coactivator RibD_C PF01872.17 KZN84517.1 - 4.9e-32 111.4 0.0 5.7e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Ank_2 PF12796.7 KZN84518.1 - 2e-38 130.9 1.0 2.7e-11 43.9 0.0 4.6 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KZN84518.1 - 4e-20 69.8 2.8 0.04 14.5 0.0 8.3 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.6 KZN84518.1 - 6.4e-19 68.1 0.6 4.7e-07 30.2 0.0 5.8 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 KZN84518.1 - 7.5e-17 60.9 7.1 0.064 13.7 0.1 7.2 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 KZN84518.1 - 3.7e-13 49.4 4.3 0.06 13.7 0.0 7.3 3 3 3 7 7 7 4 Ankyrin repeats (many copies) F-box-like PF12937.7 KZN84518.1 - 7.3e-05 22.6 2.0 0.00012 21.9 2.0 1.4 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KZN84518.1 - 0.14 12.0 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 F-box Hamartin PF04388.12 KZN84519.1 - 7.2 5.1 16.0 9 4.8 16.0 1.0 1 0 0 1 1 1 0 Hamartin protein Dyp_perox PF04261.12 KZN84520.1 - 2.1e-09 36.8 0.0 2.4e-07 30.1 0.0 2.9 3 0 0 3 3 3 2 Dyp-type peroxidase family Glyco_hydro_11 PF00457.17 KZN84523.1 - 5.4e-78 260.7 19.5 6.2e-78 260.5 19.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Sulfate_transp PF00916.20 KZN84524.1 - 1.6e-105 353.0 21.6 2.5e-105 352.3 21.6 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KZN84524.1 - 5.8e-08 32.4 0.0 1.2e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KZN84524.1 - 8e-05 23.0 3.9 8e-05 23.0 3.9 3.5 2 2 1 3 3 3 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 KZN84524.1 - 0.014 15.7 0.0 0.032 14.6 0.0 1.5 1 0 0 1 1 1 0 STAS domain SNN_transmemb PF09049.10 KZN84524.1 - 0.032 14.2 0.7 0.032 14.2 0.7 3.6 3 0 0 3 3 3 0 Stannin transmembrane Epiglycanin_C PF14654.6 KZN84524.1 - 0.79 9.8 2.8 1.1 9.4 0.8 2.2 1 1 1 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Glyco_transf_90 PF05686.12 KZN84525.1 - 2.3e-31 109.1 0.0 3.2e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 KZN84525.1 - 0.0034 17.7 0.0 0.0063 16.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Kinesin PF00225.23 KZN84526.1 - 8.1e-111 370.1 0.0 1.2e-110 369.6 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 KZN84526.1 - 1.1e-44 152.8 0.2 3.1e-44 151.3 0.2 1.9 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 KZN84526.1 - 4.6e-38 131.2 7.3 5.6e-31 108.1 0.0 3.2 4 0 0 4 4 3 2 Kinesin-associated Microtub_bd PF16796.5 KZN84526.1 - 3.2e-24 85.6 0.0 9.5e-24 84.0 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 KZN84526.1 - 1.2e-07 32.0 0.1 4.6e-07 30.2 0.1 2.1 1 0 0 1 1 1 1 Kinesin protein 1B PH PF00169.29 KZN84526.1 - 1.1e-05 25.9 0.0 3.3e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 PH domain FHA PF00498.26 KZN84526.1 - 1.5e-05 25.3 0.0 0.0001 22.6 0.0 2.6 2 0 0 2 2 2 1 FHA domain UPF0242 PF06785.11 KZN84526.1 - 0.035 14.2 9.9 1.5 8.9 0.2 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Apolipoprotein PF01442.18 KZN84526.1 - 0.095 12.6 6.4 0.48 10.3 4.0 2.8 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Ribosomal_S30AE PF02482.19 KZN84526.1 - 1.3 9.8 3.2 4.4 8.2 1.7 2.7 2 1 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein PEP-utilisers_N PF05524.13 KZN84526.1 - 3.6 7.8 4.8 5 7.3 1.3 2.5 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Seryl_tRNA_N PF02403.22 KZN84526.1 - 5 7.4 8.7 0.62 10.3 2.9 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.9 KZN84527.1 - 0.0051 16.0 0.4 0.0073 15.4 0.4 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 IFT20 PF14931.6 KZN84527.1 - 0.019 15.1 1.8 0.022 14.9 0.7 1.7 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 BLOC1_2 PF10046.9 KZN84527.1 - 0.022 15.1 5.6 2.1 8.7 0.1 3.8 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 KZN84527.1 - 0.03 14.8 0.3 11 6.6 0.9 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 KZN84527.1 - 0.045 13.8 1.4 4 7.5 0.0 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 KZN84527.1 - 0.049 12.5 0.1 0.07 12.0 0.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Cep57_MT_bd PF06657.13 KZN84527.1 - 0.059 13.8 0.7 15 6.1 0.1 3.3 2 1 2 4 4 4 0 Centrosome microtubule-binding domain of Cep57 ADIP PF11559.8 KZN84527.1 - 0.075 13.1 1.1 6.3 6.9 0.0 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2730 PF10805.8 KZN84527.1 - 0.079 13.1 0.2 0.45 10.6 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) LPP PF04728.13 KZN84527.1 - 0.083 13.3 1.3 16 6.0 0.2 3.3 2 1 1 3 3 3 0 Lipoprotein leucine-zipper PspB PF06667.12 KZN84527.1 - 0.12 12.4 2.0 16 5.6 0.0 3.1 2 1 1 3 3 3 0 Phage shock protein B DUF2062 PF09835.9 KZN84527.1 - 0.13 12.1 0.1 0.21 11.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) XhlA PF10779.9 KZN84527.1 - 0.32 11.2 5.1 1.7 8.9 0.6 3.0 3 0 0 3 3 3 0 Haemolysin XhlA DHR10 PF18595.1 KZN84527.1 - 0.91 9.6 4.0 2.7 8.1 0.9 2.6 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain DUF948 PF06103.11 KZN84527.1 - 2.3 8.5 6.0 1.7 9.0 0.1 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) CBFB_NFYA PF02045.15 KZN84528.1 - 1.5e-28 99.2 4.6 3.1e-28 98.2 4.6 1.6 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B TFIIA PF03153.13 KZN84528.1 - 0.016 15.3 25.8 0.02 14.9 25.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hus1 PF04005.12 KZN84528.1 - 0.027 13.6 0.1 0.066 12.3 0.1 1.4 1 1 0 1 1 1 0 Hus1-like protein DUF3546 PF12066.8 KZN84530.1 - 9.4e-31 106.3 2.6 9.4e-31 106.3 2.6 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 KZN84530.1 - 1.3e-13 51.8 0.4 4.7e-13 50.0 0.3 2.1 1 1 0 1 1 1 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 KZN84530.1 - 2.3e-12 46.5 0.1 5.7e-12 45.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Cnd1_N PF12922.7 KZN84530.1 - 3.2 7.6 4.4 30 4.4 0.2 2.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term bZIP_1 PF00170.21 KZN84532.1 - 0.00046 20.2 11.2 0.0014 18.6 11.2 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KZN84532.1 - 0.015 15.4 5.6 0.015 15.4 5.6 2.1 2 0 0 2 2 2 0 Basic region leucine zipper AAA_13 PF13166.6 KZN84532.1 - 0.07 11.8 0.6 0.1 11.2 0.6 1.2 1 0 0 1 1 1 0 AAA domain TEX13 PF15186.6 KZN84532.1 - 0.22 11.2 5.7 0.33 10.6 5.7 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family eIF-3_zeta PF05091.12 KZN84533.1 - 1.3e-205 684.3 0.0 1.6e-205 684.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ank_2 PF12796.7 KZN84534.1 - 1.7e-21 76.6 0.7 1.5e-16 60.8 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN84534.1 - 3.5e-20 72.1 1.4 1.1e-10 41.8 0.3 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN84534.1 - 3.2e-18 63.9 0.4 1.8e-05 24.8 0.0 3.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KZN84534.1 - 6.1e-18 64.6 3.7 3.2e-13 49.6 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KZN84534.1 - 4.3e-14 52.2 4.0 0.00051 20.4 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat CMD PF02627.20 KZN84535.1 - 2.1e-18 66.1 0.1 3.5e-18 65.4 0.1 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family NAD_binding_9 PF13454.6 KZN84536.1 - 5.9e-45 153.0 0.0 1.2e-44 152.1 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding HMG_CoA_synt_C PF08540.10 KZN84537.1 - 1.2e-98 330.2 0.7 1.4e-98 329.9 0.7 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KZN84537.1 - 2.5e-83 278.2 0.0 3.6e-83 277.7 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Hydrophobin PF01185.18 KZN84538.1 - 4.2e-06 27.3 1.5 6.2e-06 26.8 1.5 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Clathrin_bdg PF15045.6 KZN84538.1 - 0.17 11.9 0.0 0.57 10.2 0.0 1.8 2 0 0 2 2 2 0 Clathrin-binding box of Aftiphilin, vesicle trafficking Pkinase PF00069.25 KZN84539.1 - 1.4e-10 41.0 0.1 6.2e-08 32.3 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KZN84539.1 - 2.4e-07 30.3 0.2 0.00015 21.2 0.0 2.8 2 1 1 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 KZN84539.1 - 0.12 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KZN84539.1 - 0.14 10.9 0.1 0.21 10.3 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 KZN84539.1 - 0.2 11.2 0.1 0.48 10.0 0.1 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 HD_3 PF13023.6 KZN84540.1 - 1.5e-10 41.2 0.7 2.7e-10 40.4 0.7 1.4 1 0 0 1 1 1 1 HD domain ADK PF00406.22 KZN84540.1 - 9.2e-07 29.1 0.0 1.4e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KZN84540.1 - 8.7e-05 23.0 0.0 0.00015 22.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KZN84540.1 - 0.0047 17.5 0.0 0.0093 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Pkinase PF00069.25 KZN84541.1 - 4e-13 49.3 0.0 6.3e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN84541.1 - 1.8e-06 27.4 0.0 3.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KZN84541.1 - 4e-06 26.9 0.0 5.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KZN84541.1 - 4.8e-05 22.8 0.0 8.8e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KZN84541.1 - 0.00017 21.3 0.0 0.00028 20.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KZN84541.1 - 0.0027 17.3 0.0 0.0046 16.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 KZN84541.1 - 0.036 12.8 0.3 0.051 12.3 0.3 1.1 1 0 0 1 1 1 0 Fungal protein kinase WaaY PF06176.11 KZN84541.1 - 0.088 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Kinase-like PF14531.6 KZN84541.1 - 0.2 10.9 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Zn_clus PF00172.18 KZN84542.1 - 2.6e-13 49.9 34.1 8e-07 29.1 13.4 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN84542.1 - 2.6e-06 26.7 1.7 2.6e-06 26.7 1.7 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Sulfatase PF00884.23 KZN84543.1 - 2.9e-66 224.0 0.2 3.9e-66 223.5 0.2 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 KZN84543.1 - 1e-18 67.5 6.6 9.6e-18 64.3 7.1 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 KZN84543.1 - 2.7e-06 27.2 4.4 2.7e-06 27.2 4.4 2.1 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KZN84543.1 - 0.046 12.3 0.0 0.088 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Sugar_tr PF00083.24 KZN84544.1 - 9.4e-74 248.9 21.1 1.1e-73 248.7 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN84544.1 - 1.4e-12 47.3 37.7 1.4e-12 47.3 37.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KZN84544.1 - 6.5e-05 21.7 3.3 6.5e-05 21.7 3.3 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein Cupin_1 PF00190.22 KZN84545.1 - 2.7e-40 137.4 0.0 7.6e-19 67.8 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KZN84545.1 - 5.6e-23 80.4 0.4 4e-12 45.7 0.2 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KZN84545.1 - 3.4e-08 33.1 0.0 0.01 15.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KZN84545.1 - 3.4e-07 30.2 0.0 0.00058 19.8 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.18 KZN84545.1 - 0.00082 19.3 0.0 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Cupin_6 PF12852.7 KZN84545.1 - 0.016 14.9 0.0 0.83 9.4 0.0 2.3 2 0 0 2 2 2 0 Cupin Cupin_4 PF08007.12 KZN84545.1 - 0.042 13.3 0.0 0.42 10.0 0.0 2.0 2 0 0 2 2 2 0 Cupin superfamily protein ARD PF03079.14 KZN84545.1 - 0.088 13.0 0.1 0.44 10.7 0.0 1.9 2 0 0 2 2 2 0 ARD/ARD' family MFS_1 PF07690.16 KZN84546.1 - 7.1e-23 81.1 24.2 2.5e-19 69.4 17.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily M20_dimer PF07687.14 KZN84547.1 - 1.6e-09 37.6 0.0 3.6e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KZN84547.1 - 7.9e-08 32.2 0.1 1.5e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Fungal_trans_2 PF11951.8 KZN84548.1 - 4.4e-13 48.8 1.9 1.4e-11 43.8 1.9 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain AAA PF00004.29 KZN84549.1 - 8.2e-43 146.0 0.7 8.4e-14 52.1 0.0 5.2 6 0 0 6 6 4 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 KZN84549.1 - 1.5e-40 139.0 0.0 2.8e-39 134.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KZN84549.1 - 8.8e-28 97.8 28.7 2.7e-25 89.6 0.0 6.6 7 0 0 7 7 6 2 AAA domain AAA_19 PF13245.6 KZN84549.1 - 3e-17 63.3 2.7 4.4e-08 33.6 0.0 5.9 5 1 0 5 5 5 2 AAA domain AAA_30 PF13604.6 KZN84549.1 - 2.8e-16 59.8 0.1 8.4e-06 25.6 0.0 5.7 5 0 0 5 5 5 3 AAA domain AAA_lid_6 PF17866.1 KZN84549.1 - 1.1e-14 54.4 3.3 6e-06 26.4 0.8 3.7 3 0 0 3 3 3 2 AAA lid domain AAA_5 PF07728.14 KZN84549.1 - 9.8e-14 51.5 0.4 0.07 13.1 0.1 4.9 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KZN84549.1 - 6e-10 39.1 0.0 0.0049 16.6 0.0 4.7 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_22 PF13401.6 KZN84549.1 - 1.6e-09 38.2 6.8 0.25 11.6 0.0 6.5 4 3 0 4 4 4 3 AAA domain Mg_chelatase PF01078.21 KZN84549.1 - 7.4e-09 35.3 0.7 0.33 10.3 0.0 4.9 5 0 0 5 5 4 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KZN84549.1 - 1.7e-08 35.0 7.7 0.24 11.8 0.0 6.2 6 0 0 6 6 4 3 AAA ATPase domain RNA_helicase PF00910.22 KZN84549.1 - 5e-08 33.3 0.1 0.56 10.6 0.0 4.8 4 0 0 4 4 4 1 RNA helicase ResIII PF04851.15 KZN84549.1 - 1.8e-07 31.3 0.2 0.00013 22.0 0.0 4.7 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit RuvB_N PF05496.12 KZN84549.1 - 7.3e-07 29.1 0.2 3.3 7.4 0.0 4.7 4 1 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KZN84549.1 - 2.7e-06 28.0 6.5 1.8 9.1 0.0 6.4 6 0 0 6 6 5 1 AAA domain AAA_7 PF12775.7 KZN84549.1 - 6.7e-06 25.7 0.2 14 5.2 0.0 4.8 4 0 0 4 4 4 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 KZN84549.1 - 1.1e-05 25.3 4.9 0.34 10.6 0.0 6.0 7 0 0 7 7 7 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KZN84549.1 - 5.3e-05 22.6 6.5 0.00086 18.6 0.0 5.2 6 1 1 7 7 6 1 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 KZN84549.1 - 6.2e-05 22.8 0.1 9 6.0 0.0 5.1 5 0 0 5 5 5 0 Sigma-54 interaction domain AAA_28 PF13521.6 KZN84549.1 - 0.00021 21.5 3.2 2.7 8.2 0.1 5.1 4 0 0 4 4 4 1 AAA domain AAA_24 PF13479.6 KZN84549.1 - 0.00025 20.9 3.9 7.5 6.2 0.0 4.5 4 0 0 4 4 4 0 AAA domain PhoH PF02562.16 KZN84549.1 - 0.00037 20.0 0.2 1.5 8.2 0.0 4.4 4 0 0 4 4 4 1 PhoH-like protein ABC_tran PF00005.27 KZN84549.1 - 0.00078 20.0 2.6 13 6.3 0.0 5.1 5 0 0 5 5 4 0 ABC transporter Adeno_IVa2 PF02456.15 KZN84549.1 - 0.0012 17.7 0.0 0.034 13.0 0.0 2.3 2 0 0 2 2 2 1 Adenovirus IVa2 protein Torsin PF06309.11 KZN84549.1 - 0.0016 18.5 0.1 22 5.2 0.0 4.3 4 0 0 4 4 4 0 Torsin AAA_33 PF13671.6 KZN84549.1 - 0.031 14.4 17.6 1.7 8.8 0.1 5.6 6 0 0 6 6 5 0 AAA domain SKI PF01202.22 KZN84549.1 - 0.041 14.0 2.0 31 4.6 0.0 4.5 4 0 0 4 4 4 0 Shikimate kinase NACHT PF05729.12 KZN84549.1 - 0.062 13.2 2.3 18 5.2 0.0 4.2 4 0 0 4 4 4 0 NACHT domain Helicase_RecD PF05127.14 KZN84549.1 - 0.076 12.9 0.0 0.73 9.7 0.0 2.8 2 0 0 2 2 2 0 Helicase AAA_29 PF13555.6 KZN84549.1 - 0.077 12.7 0.7 39 4.1 0.0 3.8 4 0 0 4 4 4 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KZN84549.1 - 0.13 11.8 5.0 2.2 7.8 0.0 3.6 4 0 0 4 4 4 0 AAA domain SRP54 PF00448.22 KZN84549.1 - 0.58 9.8 2.2 19 4.8 0.0 3.7 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 KZN84549.1 - 0.75 9.7 3.8 12 5.8 0.0 4.2 5 0 0 5 5 4 0 NTPase Vanabin-2 PF11437.8 KZN84549.1 - 2.4 8.4 15.8 6.4 7.0 15.8 1.7 1 0 0 1 1 1 0 Vanadium-binding protein 2 RsgA_GTPase PF03193.16 KZN84549.1 - 3.1 7.7 5.3 8.2 6.3 0.1 3.7 4 0 0 4 4 3 0 RsgA GTPase WD40 PF00400.32 KZN84551.1 - 6.4e-54 178.7 16.7 5.1e-09 36.6 0.2 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN84551.1 - 7.1e-15 55.1 0.5 0.00026 21.2 0.0 4.4 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KZN84551.1 - 0.0022 16.7 1.4 1.3 7.6 0.0 3.0 1 1 2 4 4 4 2 Nucleoporin Nup120/160 LisH PF08513.11 KZN84551.1 - 0.01 15.8 0.1 0.019 14.9 0.1 1.5 1 0 0 1 1 1 0 LisH Nucleoporin_N PF08801.11 KZN84551.1 - 0.031 13.0 0.4 1.7 7.3 0.0 3.3 1 1 2 3 3 3 0 Nup133 N terminal like Ribonuclease_3 PF00636.26 KZN84553.1 - 5.8e-08 33.3 0.0 1.2e-07 32.2 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KZN84553.1 - 9e-06 25.9 0.0 1.2e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like Rhabdo_M1 PF03342.13 KZN84553.1 - 0.023 14.1 0.0 0.026 13.9 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) TFR_dimer PF04253.15 KZN84553.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain Abhydro_lipase PF04083.16 KZN84555.1 - 9.5e-21 73.1 0.0 1.9e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KZN84555.1 - 9.5e-06 25.4 0.1 2.1e-05 24.3 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KZN84555.1 - 0.013 14.8 0.0 0.044 13.0 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KZN84555.1 - 0.12 11.3 0.0 0.25 10.2 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase enzyme MFS_1 PF07690.16 KZN84556.1 - 7.2e-40 137.0 53.9 2.9e-38 131.7 50.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1418 PF07214.12 KZN84556.1 - 0.1 12.4 0.0 0.1 12.4 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1418) Arylsulfotran_2 PF14269.6 KZN84557.1 - 5e-120 400.4 0.2 6.4e-120 400.0 0.2 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Glyco_hydro_43 PF04616.14 KZN84558.1 - 2.6e-33 115.6 3.1 3.8e-33 115.0 3.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_3 PF00933.21 KZN84559.1 - 1.8e-58 198.4 0.0 2.2e-58 198.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Cation_efflux PF01545.21 KZN84560.1 - 2.2e-52 177.7 0.2 4.5e-52 176.7 0.2 1.5 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KZN84560.1 - 0.019 15.1 0.2 0.036 14.2 0.2 1.4 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter Zip PF02535.22 KZN84560.1 - 0.031 13.5 5.2 0.78 8.9 3.7 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter Metallophos PF00149.28 KZN84561.1 - 7.5e-09 36.4 0.0 4.2e-08 33.9 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Sugar_tr PF00083.24 KZN84562.1 - 6.7e-127 424.1 25.6 7.6e-127 423.9 25.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN84562.1 - 4.4e-23 81.8 32.5 1.6e-16 60.2 8.4 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.6 KZN84562.1 - 0.037 14.5 0.1 0.072 13.6 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Ilm1 PF10311.9 KZN84562.1 - 0.042 13.5 0.7 0.086 12.5 0.7 1.5 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 MadM PF03818.13 KZN84562.1 - 8.3 6.4 10.3 5.6 6.9 0.5 3.8 3 0 0 3 3 3 0 Malonate/sodium symporter MadM subunit HET PF06985.11 KZN84563.1 - 5.5e-10 39.8 0.4 2.7e-06 27.8 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Lipase_GDSL_2 PF13472.6 KZN84564.1 - 8.1e-17 62.2 0.0 1.1e-16 61.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KZN84564.1 - 2.8e-12 47.1 0.0 3.1e-12 46.9 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KZN84564.1 - 1.1e-06 28.8 0.1 2.5e-06 27.7 0.0 1.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Nbl1_Borealin_N PF10444.9 KZN84564.1 - 0.0093 15.6 0.4 0.23 11.1 0.1 2.2 2 0 0 2 2 2 1 Nbl1 / Borealin N terminal PhyH PF05721.13 KZN84565.1 - 1.5e-15 58.1 0.0 1.8e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Med21 PF11221.8 KZN84565.1 - 0.032 14.5 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Fungal_trans_2 PF11951.8 KZN84566.1 - 7.7e-12 44.7 4.7 3.9e-11 42.4 1.5 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain Sugar_tr PF00083.24 KZN84567.1 - 2.2e-115 386.1 21.8 3.3e-115 385.5 21.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN84567.1 - 1e-28 100.3 40.3 7.7e-25 87.6 23.4 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KZN84567.1 - 0.0025 16.3 3.2 0.0025 16.3 3.2 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) UPF0016 PF01169.19 KZN84567.1 - 0.4 11.0 6.8 6.3 7.2 0.1 3.5 3 0 0 3 3 3 0 Uncharacterized protein family UPF0016 Glyco_transf_28 PF03033.20 KZN84569.1 - 3.9e-19 69.1 0.0 4.1e-14 52.8 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain ATG_C PF09333.11 KZN84569.1 - 1.2e-06 28.8 0.0 4.8e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 KZN84569.1 - 5.8e-05 23.1 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 KZN84569.1 - 8.4e-05 21.5 0.0 0.00014 20.9 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase HDOD PF08668.12 KZN84571.1 - 0.14 11.6 0.1 0.2 11.1 0.1 1.2 1 0 0 1 1 1 0 HDOD domain Cucumopine_C PF18631.1 KZN84572.1 - 2.9e-54 182.9 0.1 4.1e-54 182.3 0.1 1.2 1 0 0 1 1 1 1 Cucumopine synthase C-terminal helical bundle domain DUF202 PF02656.15 KZN84573.1 - 6e-15 55.4 3.2 6e-15 55.4 3.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) GFA PF04828.14 KZN84574.1 - 2.7e-18 66.1 1.8 4.6e-18 65.4 1.8 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Methyltransf_25 PF13649.6 KZN84575.1 - 8.4e-17 61.7 0.0 3.4e-16 59.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN84575.1 - 2.7e-14 53.6 0.0 5.6e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN84575.1 - 6.9e-13 49.2 0.0 1.4e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN84575.1 - 2.3e-11 43.8 0.0 3.7e-11 43.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN84575.1 - 4e-11 42.9 0.0 5.5e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KZN84575.1 - 6.7e-07 29.0 0.0 1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KZN84575.1 - 7e-06 25.5 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 KZN84575.1 - 0.00011 21.8 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.20 KZN84575.1 - 0.00012 21.3 0.0 0.00016 20.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.11 KZN84575.1 - 0.0015 17.6 0.0 0.0036 16.3 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.19 KZN84575.1 - 0.0019 18.0 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KZN84575.1 - 0.0034 16.8 0.0 0.0062 16.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.12 KZN84575.1 - 0.0052 15.9 0.0 0.009 15.1 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase CMAS PF02353.20 KZN84575.1 - 0.041 13.2 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Pox_MCEL PF03291.16 KZN84575.1 - 0.052 12.7 0.0 0.078 12.1 0.0 1.3 1 1 0 1 1 1 0 mRNA capping enzyme Methyltransf_32 PF13679.6 KZN84575.1 - 0.06 13.3 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 KZN84575.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_5 PF01795.19 KZN84575.1 - 0.15 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family DHHC PF01529.20 KZN84576.1 - 1.1e-32 113.0 5.7 1.1e-32 113.0 5.7 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4636 PF15468.6 KZN84576.1 - 1.5 8.5 5.8 0.17 11.6 1.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4636) adh_short_C2 PF13561.6 KZN84577.1 - 2.8e-50 171.1 0.0 3.6e-50 170.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN84577.1 - 4.4e-43 147.0 0.0 5.2e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN84577.1 - 2e-07 31.1 0.0 2.8e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KZN84577.1 - 0.0013 18.2 0.0 0.0025 17.2 0.0 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_7 PF13241.6 KZN84577.1 - 0.026 14.9 0.4 0.14 12.6 0.7 2.0 2 1 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 KZN84577.1 - 0.031 13.6 0.1 0.086 12.1 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_3 PF03447.16 KZN84578.1 - 0.045 14.4 0.0 0.25 12.0 0.0 2.1 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain DNA_mis_repair PF01119.19 KZN84579.1 - 3.9e-09 36.2 0.0 9.5e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 KZN84579.1 - 4.3e-09 36.9 0.3 4.3e-08 33.6 0.1 2.6 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KZN84579.1 - 2.3e-08 33.9 0.0 5e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1295 PF06966.12 KZN84580.1 - 1.1e-34 120.0 0.0 1.6e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 KZN84580.1 - 2.1e-05 24.6 0.0 4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 KZN84580.1 - 0.0017 18.7 0.1 0.0043 17.4 0.1 1.7 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 KZN84580.1 - 0.0034 17.8 0.0 0.0085 16.5 0.0 1.7 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family BPD_transp_1 PF00528.22 KZN84580.1 - 0.0041 16.9 0.1 0.012 15.3 0.0 1.6 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component ERG4_ERG24 PF01222.17 KZN84580.1 - 0.041 12.6 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family 2-Hacid_dh_C PF02826.19 KZN84582.1 - 3.5e-37 127.5 0.1 1.1e-24 86.8 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KZN84582.1 - 0.0072 16.0 0.0 0.014 15.0 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3HCDH_N PF02737.18 KZN84582.1 - 0.032 14.1 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DinI PF06183.13 KZN84582.1 - 0.1 13.0 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 DinI-like family MetJ PF01340.20 KZN84582.1 - 0.12 12.3 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Met Apo-repressor, MetJ Acetyltransf_1 PF00583.25 KZN84583.1 - 1.2e-11 44.9 0.0 1.5e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KZN84583.1 - 5.6e-10 39.2 0.0 9.6e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KZN84583.1 - 8.6e-10 38.9 0.0 1.1e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KZN84583.1 - 0.00027 21.0 0.1 0.0085 16.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KZN84583.1 - 0.00085 19.4 0.0 0.0018 18.4 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KZN84583.1 - 0.005 16.8 0.0 0.055 13.4 0.0 2.2 2 1 0 2 2 2 1 FR47-like protein CFEM PF05730.11 KZN84585.1 - 8.3e-06 25.8 8.5 1.6e-05 24.9 8.5 1.4 1 0 0 1 1 1 1 CFEM domain Glyco_hydro_64 PF16483.5 KZN84586.1 - 4.2e-116 388.2 0.1 5e-116 388.0 0.1 1.1 1 0 0 1 1 1 1 Beta-1,3-glucanase Glyco_transf_28 PF03033.20 KZN84587.1 - 2.3e-20 73.1 0.0 6.3e-20 71.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KZN84587.1 - 0.0025 16.7 0.0 0.005 15.7 0.0 1.5 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase VPS13_C PF16909.5 KZN84587.1 - 0.019 14.8 0.2 0.099 12.4 0.3 2.2 2 0 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal zf-Tim10_DDP PF02953.15 KZN84587.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Tim10/DDP family zinc finger DUF2985 PF11204.8 KZN84588.1 - 4.4e-38 129.3 1.7 4.4e-38 129.3 1.7 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF2985) DUF3042 PF11240.8 KZN84588.1 - 0.051 13.6 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Phage_holin_3_6 PF07332.11 KZN84588.1 - 0.18 11.9 3.6 0.26 11.4 0.9 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III MFS_1 PF07690.16 KZN84589.1 - 1.5e-45 155.7 48.2 1.4e-44 152.5 49.5 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KZN84589.1 - 2.8e-22 78.9 27.6 6.1e-22 77.8 27.6 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KZN84589.1 - 4.6e-13 48.9 11.9 4.6e-13 48.9 11.9 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KZN84589.1 - 0.3 9.3 15.7 0.16 10.2 3.3 3.1 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family ADH_N PF08240.12 KZN84590.1 - 7.5e-30 103.0 4.0 7.6e-30 103.0 0.6 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN84590.1 - 5e-16 58.9 0.1 1.4e-15 57.4 0.1 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KZN84590.1 - 7.7e-07 28.8 0.2 0.00089 18.8 0.0 2.4 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KZN84590.1 - 4.4e-05 22.9 0.1 7.8e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KZN84590.1 - 0.00049 21.2 0.0 0.0011 20.0 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 KZN84590.1 - 0.0064 16.1 0.1 0.01 15.4 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 KZN84590.1 - 0.013 15.4 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain gpW PF02831.15 KZN84590.1 - 0.033 14.1 0.0 2.1 8.3 0.0 2.5 2 0 0 2 2 2 0 gpW Pyr_redox_2 PF07992.14 KZN84590.1 - 0.043 13.0 0.3 0.079 12.2 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KZN84590.1 - 0.062 13.7 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding HI0933_like PF03486.14 KZN84590.1 - 0.079 11.7 0.4 0.14 10.8 0.4 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KZN84590.1 - 0.1 13.1 0.8 0.25 11.9 0.8 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 KZN84591.1 - 3.7e-68 229.8 0.0 5.4e-68 229.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN84591.1 - 3.6e-42 144.4 0.0 5.6e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 KZN84591.1 - 3.5e-08 33.5 0.2 0.0045 17.1 0.0 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 KZN84591.1 - 1.2e-06 28.1 0.0 1.9e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KZN84591.1 - 0.054 12.4 0.0 0.083 11.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KZN84591.1 - 0.38 9.5 0.0 0.38 9.5 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase MFMR_assoc PF16596.5 KZN84591.1 - 3.4 8.1 9.9 15 6.1 0.6 2.5 2 0 0 2 2 2 0 Disordered region downstream of MFMR AA_permease PF00324.21 KZN84593.1 - 1.2e-109 367.0 37.6 1.5e-109 366.8 37.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KZN84593.1 - 5.1e-28 98.1 43.0 1.1e-27 97.0 42.9 1.5 1 1 0 1 1 1 1 Amino acid permease CHAD PF05235.14 KZN84595.1 - 0.063 13.2 0.0 0.082 12.9 0.0 1.2 1 0 0 1 1 1 0 CHAD domain OPA3 PF07047.12 KZN84596.1 - 1.3e-47 160.6 3.2 2.1e-47 160.0 3.2 1.3 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) BatD PF13584.6 KZN84596.1 - 0.0093 14.8 0.6 0.0093 14.8 0.6 1.5 2 0 0 2 2 2 1 Oxygen tolerance Troponin PF00992.20 KZN84596.1 - 0.033 14.5 0.4 0.033 14.5 0.4 1.8 1 1 1 2 2 2 0 Troponin Mucin PF01456.17 KZN84596.1 - 0.93 9.5 10.2 14 5.6 0.0 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Myosin_head PF00063.21 KZN84598.1 - 9.6e-244 810.6 0.6 1.1e-243 810.4 0.6 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KZN84598.1 - 1.1e-53 181.7 0.0 2.1e-53 180.8 0.0 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 KZN84598.1 - 1.7e-12 46.7 0.2 4.3e-12 45.4 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KZN84598.1 - 2.7e-08 33.5 0.0 7.1e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KZN84598.1 - 5.2e-08 32.5 0.0 1.5e-07 31.0 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.27 KZN84598.1 - 0.018 14.8 9.7 0.61 10.0 1.0 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_16 PF13191.6 KZN84598.1 - 0.032 14.6 0.0 0.16 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Hpr_kinase_C PF07475.12 KZN84598.1 - 0.047 13.2 1.2 9.1 5.8 0.0 2.9 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.6 KZN84598.1 - 0.057 13.7 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KZN84598.1 - 0.11 12.4 0.1 0.29 11.0 0.1 1.7 1 0 0 1 1 1 0 NACHT domain SH3_3 PF08239.11 KZN84598.1 - 0.12 12.7 0.4 0.3 11.4 0.4 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain p450 PF00067.22 KZN84600.1 - 9.6e-70 235.6 0.0 1.1e-69 235.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3759 PF12585.8 KZN84601.1 - 0.007 16.4 1.1 0.007 16.4 1.1 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3759) Chitin_synth_2 PF03142.15 KZN84602.1 - 1.8e-290 964.1 0.3 2.2e-290 963.8 0.3 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KZN84602.1 - 9.9e-12 45.2 4.5 3.3e-11 43.5 4.5 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KZN84602.1 - 1.4e-08 34.9 0.0 1.3e-07 31.8 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KZN84602.1 - 0.00075 19.3 0.0 0.066 13.0 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KZN84602.1 - 0.0074 15.8 0.1 0.021 14.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 21 Sel1 PF08238.12 KZN84603.1 - 1.7e-40 136.6 15.2 4.2e-07 30.4 0.0 7.4 7 0 0 7 7 7 7 Sel1 repeat Arrestin_N PF00339.29 KZN84604.1 - 2.6e-08 34.0 0.1 1.7e-07 31.4 0.0 2.3 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KZN84604.1 - 1.1e-06 29.2 0.1 0.00011 22.7 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Fungal_trans PF04082.18 KZN84605.1 - 9.6e-11 41.2 1.4 1.7e-10 40.4 0.1 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain COesterase PF00135.28 KZN84606.1 - 2.3e-54 185.2 0.0 3.2e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KZN84606.1 - 1e-07 32.0 1.3 0.0093 15.8 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold MFS_1 PF07690.16 KZN84607.1 - 1.4e-37 129.4 37.3 1.4e-37 129.4 37.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1218 PF06749.12 KZN84607.1 - 0.024 15.2 0.0 0.024 15.2 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1218) HpcH_HpaI PF03328.14 KZN84608.1 - 1.8e-29 102.5 0.0 2.5e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family 2-Hacid_dh_C PF02826.19 KZN84609.1 - 5.1e-48 162.8 0.0 6.8e-48 162.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KZN84609.1 - 3.8e-23 81.6 0.0 4.5e-23 81.4 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 KZN84609.1 - 0.0019 18.3 0.0 0.0034 17.5 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 KZN84609.1 - 0.0092 16.2 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KZN84609.1 - 0.06 12.9 0.0 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Fungal_trans PF04082.18 KZN84610.1 - 0.069 12.2 0.1 5.5 5.9 0.0 2.7 1 1 1 2 2 2 0 Fungal specific transcription factor domain MAGI_u5 PF16666.5 KZN84610.1 - 3 8.0 7.8 2.6 8.2 0.8 2.5 2 0 0 2 2 2 0 Unstructured region on MAGI PARP PF00644.20 KZN84612.1 - 2.1e-58 197.2 0.0 5.9e-58 195.7 0.0 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KZN84612.1 - 1.5e-41 141.7 0.0 3e-41 140.7 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KZN84612.1 - 2e-19 69.4 0.4 4.2e-19 68.4 0.4 1.6 1 0 0 1 1 1 1 WGR domain BRCT PF00533.26 KZN84612.1 - 9.9e-09 35.5 0.1 2.1e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KZN84612.1 - 4.5e-07 29.7 0.1 1.9e-06 27.7 0.1 2.1 2 0 0 2 2 2 1 twin BRCT domain BRCT_2 PF16589.5 KZN84612.1 - 2.3e-05 24.7 0.1 5.7e-05 23.4 0.1 1.7 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain NACHT_N PF17100.5 KZN84613.1 - 4.5e-63 213.1 0.0 9.4e-63 212.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase WD40 PF00400.32 KZN84613.1 - 1.7e-35 120.4 23.7 1.2e-07 32.3 0.0 11.3 12 0 0 12 12 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN84613.1 - 6.1e-24 84.1 0.2 0.0039 17.4 0.0 9.9 2 2 6 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KZN84613.1 - 5.3e-14 52.5 0.0 1.2e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.12 KZN84613.1 - 2.3e-09 37.0 9.9 0.43 10.6 0.1 9.3 10 0 0 10 10 10 3 WD40-like Beta Propeller Repeat AAA_16 PF13191.6 KZN84613.1 - 8.2e-06 26.3 0.0 9.6e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Proteasome_A_N PF10584.9 KZN84613.1 - 2.3e-05 24.0 0.3 7.4 6.4 0.0 5.8 5 0 0 5 5 5 1 Proteasome subunit A N-terminal signature DUF1513 PF07433.11 KZN84613.1 - 0.0035 16.5 0.1 1.1 8.2 0.0 3.8 3 1 0 4 4 4 1 Protein of unknown function (DUF1513) AAA PF00004.29 KZN84613.1 - 0.0042 17.5 0.0 0.014 15.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KZN84613.1 - 0.074 13.4 0.0 0.57 10.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Ge1_WD40 PF16529.5 KZN84613.1 - 0.43 9.5 11.3 28 3.5 0.3 6.7 3 1 5 8 8 8 0 WD40 region of Ge1, enhancer of mRNA-decapping protein APH PF01636.23 KZN84614.1 - 4.9e-11 43.0 0.1 5.2e-11 42.9 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN84614.1 - 0.0008 19.1 0.0 0.00098 18.8 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KZN84614.1 - 0.0046 16.4 0.0 0.0046 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Alpha-mann_mid PF09261.11 KZN84616.1 - 0.12 12.5 0.2 0.28 11.4 0.0 1.6 2 0 0 2 2 2 0 Alpha mannosidase middle domain PfkB PF00294.24 KZN84617.1 - 5.7e-39 134.2 0.9 7e-39 133.9 0.9 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Zn_clus PF00172.18 KZN84618.1 - 0.0074 16.4 0.6 0.014 15.6 0.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_C14 PF00656.22 KZN84619.1 - 5.5e-06 26.5 0.1 2.1e-05 24.6 0.1 1.8 1 1 0 1 1 1 1 Caspase domain DUF218 PF02698.17 KZN84619.1 - 0.13 12.3 0.2 0.94 9.5 0.0 2.1 2 0 0 2 2 2 0 DUF218 domain Raptor_N PF14538.6 KZN84619.1 - 0.7 9.8 3.2 1.8 8.5 0.1 2.6 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain DUF3716 PF12511.8 KZN84620.1 - 2.5e-14 53.0 1.6 3.7e-14 52.5 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF4404 PF14357.6 KZN84620.1 - 0.21 12.3 1.6 0.33 11.6 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) DUF3716 PF12511.8 KZN84621.1 - 2.7e-14 52.9 2.7 4.2e-14 52.3 2.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) HNH_2 PF13391.6 KZN84623.1 - 0.00095 19.3 0.1 0.0015 18.6 0.1 1.4 1 0 0 1 1 1 1 HNH endonuclease Sugar_tr PF00083.24 KZN84625.1 - 1.6e-108 363.5 28.4 5.2e-108 361.8 28.4 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN84625.1 - 2.6e-21 76.0 60.2 3.3e-14 52.6 24.9 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily OATP PF03137.20 KZN84625.1 - 4.7 5.4 13.7 0.07 11.4 5.4 2.1 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans_2 PF11951.8 KZN84626.1 - 7.2e-10 38.2 0.1 1.9e-09 36.8 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Auto_anti-p27 PF06677.12 KZN84627.1 - 2 8.6 4.6 0.62 10.3 1.2 1.9 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) NmrA PF05368.13 KZN84628.1 - 1.6e-11 44.2 0.0 1.1e-08 34.9 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 KZN84628.1 - 1e-06 28.7 0.0 3.2e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KZN84629.1 - 2.9e-34 118.4 0.0 3.9e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KZN84629.1 - 6.8e-05 22.4 0.0 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ketoacyl-synt PF00109.26 KZN84630.1 - 3.1e-64 217.0 0.0 6.4e-64 215.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KZN84630.1 - 4.7e-59 200.0 0.0 7.9e-59 199.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KZN84630.1 - 7.8e-59 199.7 0.0 1.4e-58 199.0 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KZN84630.1 - 7e-58 195.5 0.1 1.3e-57 194.6 0.1 1.5 1 0 0 1 1 1 1 KR domain KAsynt_C_assoc PF16197.5 KZN84630.1 - 9.5e-29 100.1 1.0 1.5e-27 96.2 0.0 2.9 3 0 0 3 3 2 1 Ketoacyl-synthetase C-terminal extension Ketoacyl-synt_C PF02801.22 KZN84630.1 - 1.2e-27 96.2 0.6 2.5e-27 95.2 0.6 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KZN84630.1 - 6.7e-18 65.3 0.0 1.8e-17 63.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KZN84630.1 - 2.4e-16 61.0 0.0 4.8e-15 56.8 0.0 3.0 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 KZN84630.1 - 1.9e-12 47.3 0.0 4.8e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN84630.1 - 7.7e-11 42.6 0.0 2.3e-10 41.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN84630.1 - 3.7e-09 37.1 0.0 1e-08 35.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KZN84630.1 - 3.9e-09 36.3 0.0 8.6e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_31 PF13847.6 KZN84630.1 - 1.7e-08 34.4 0.0 3.3e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KZN84630.1 - 8.3e-08 32.3 1.3 6.5e-07 29.4 0.0 2.8 3 0 0 3 3 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 KZN84630.1 - 1.2e-05 25.6 0.0 0.00012 22.4 0.0 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site ADH_N PF08240.12 KZN84630.1 - 3.2e-05 23.8 0.2 0.00012 21.9 0.2 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short_C2 PF13561.6 KZN84630.1 - 5.9e-05 22.7 0.0 0.00013 21.6 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 KZN84630.1 - 0.00019 20.9 0.1 0.00043 19.7 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 KZN84630.1 - 0.00022 20.6 0.0 0.00042 19.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KZN84630.1 - 0.0025 17.6 0.0 0.0067 16.2 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_24 PF13578.6 KZN84630.1 - 0.013 16.6 0.0 0.082 13.9 0.0 2.6 3 0 0 3 3 1 0 Methyltransferase domain ACP_syn_III PF08545.10 KZN84630.1 - 0.038 13.8 0.3 0.095 12.6 0.3 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Acetyltransf_2 PF00797.17 KZN84632.1 - 8.1e-27 94.5 0.1 1.1e-26 94.1 0.1 1.1 1 0 0 1 1 1 1 N-acetyltransferase GDPD PF03009.17 KZN84633.1 - 2.4e-13 50.4 0.0 4.3e-13 49.6 0.0 1.5 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family ATPgrasp_N PF18130.1 KZN84633.1 - 0.054 14.1 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp N-terminal domain RsmJ PF04378.13 KZN84633.1 - 0.13 11.5 0.0 0.38 9.9 0.0 1.7 2 0 0 2 2 2 0 Ribosomal RNA large subunit methyltransferase D, RlmJ CDC24_OB2 PF17245.2 KZN84634.1 - 0.13 12.9 0.0 0.16 12.5 0.0 1.3 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 2 Zip PF02535.22 KZN84635.1 - 1.3e-56 192.3 0.6 1.9e-56 191.7 0.6 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter UNC-50 PF05216.13 KZN84635.1 - 0.53 9.8 5.0 0.2 11.2 2.3 1.6 2 0 0 2 2 2 0 UNC-50 family bZIP_1 PF00170.21 KZN84636.1 - 4.8e-06 26.6 27.7 1.2e-05 25.3 14.1 3.3 1 1 2 3 3 3 2 bZIP transcription factor bZIP_2 PF07716.15 KZN84636.1 - 0.024 14.7 27.5 0.027 14.5 13.0 3.3 2 1 1 3 3 3 0 Basic region leucine zipper Exonuc_VII_L PF02601.15 KZN84636.1 - 0.07 12.7 5.3 0.12 12.0 5.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 KZN84636.1 - 0.097 11.5 12.4 0.15 10.9 12.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein bZIP_Maf PF03131.17 KZN84636.1 - 0.51 10.9 18.4 0.15 12.6 9.3 2.9 1 1 1 2 2 2 0 bZIP Maf transcription factor LSR PF05624.14 KZN84636.1 - 2.2 8.4 5.9 0.68 10.0 1.1 2.2 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) APG6_N PF17675.1 KZN84636.1 - 2.5 8.6 19.4 5.2 7.6 19.4 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region zf-CCCH PF00642.24 KZN84637.1 - 5.8e-16 58.0 30.1 2.7e-05 24.0 1.1 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KZN84637.1 - 1.3e-10 41.0 29.2 0.0063 16.5 0.8 6.1 5 1 0 5 5 5 4 Zinc finger domain zf-CCCH_3 PF15663.5 KZN84637.1 - 1.6e-05 25.1 16.5 0.002 18.4 2.1 3.7 1 1 2 3 3 3 3 Zinc-finger containing family zf-CCCH_4 PF18044.1 KZN84637.1 - 0.0079 16.0 23.8 0.033 14.0 0.0 5.3 5 1 0 5 5 5 2 CCCH-type zinc finger Torus PF16131.5 KZN84637.1 - 0.044 14.5 28.1 0.89 10.3 0.6 4.9 2 1 3 5 5 5 0 Torus domain zf-C3H1 PF10650.9 KZN84637.1 - 0.055 13.2 0.3 0.055 13.2 0.3 4.4 5 0 0 5 5 5 0 Putative zinc-finger domain Ebp2 PF05890.12 KZN84637.1 - 0.19 11.3 4.8 0.38 10.3 4.8 1.4 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 TFIIF_beta_N PF17683.1 KZN84638.1 - 5.2e-31 108.1 0.1 9.9e-31 107.2 0.1 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 KZN84638.1 - 6.1e-28 96.7 0.3 1e-27 96.0 0.3 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Tau95 PF09734.9 KZN84638.1 - 0.005 17.6 0.4 0.0094 16.8 0.4 1.6 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain PCI PF01399.27 KZN84640.1 - 1.3e-12 48.2 0.0 3.3e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.9 KZN84640.1 - 7.1e-06 25.8 0.7 1.2e-05 25.1 0.7 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_19 PF14559.6 KZN84640.1 - 0.0078 16.7 1.4 4.5 7.9 0.4 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat Herpes_UL14 PF03580.14 KZN84640.1 - 0.0091 16.2 2.6 2.1 8.6 0.1 2.5 1 1 1 2 2 2 2 Herpesvirus UL14-like protein PspA_IM30 PF04012.12 KZN84640.1 - 0.012 15.2 1.6 0.026 14.1 1.6 1.5 1 0 0 1 1 1 0 PspA/IM30 family TPR_16 PF13432.6 KZN84640.1 - 0.09 13.4 2.6 4 8.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KZN84640.1 - 1.2 10.1 5.9 37 5.5 0.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Aldedh PF00171.22 KZN84642.1 - 1.8e-129 432.2 0.9 2.4e-76 257.1 0.9 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family HopA1 PF17914.1 KZN84642.1 - 0.033 13.9 0.0 8 6.2 0.0 2.5 2 0 0 2 2 2 0 HopA1 effector protein family FAD_binding_2 PF00890.24 KZN84643.1 - 3.3e-85 286.7 0.8 4.2e-85 286.3 0.8 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 KZN84643.1 - 4.7e-20 71.5 0.1 3.2e-19 68.8 0.0 2.4 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 KZN84643.1 - 2.2e-14 53.8 0.7 5.3e-14 52.6 0.6 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KZN84643.1 - 7.4e-09 35.2 0.6 2.3e-07 30.3 0.4 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN84643.1 - 3.8e-08 33.4 0.6 2.5e-07 30.8 0.3 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KZN84643.1 - 1.4e-07 31.2 1.2 4.4e-07 29.6 1.2 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KZN84643.1 - 1.6e-07 30.4 0.9 0.0034 16.1 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.6 KZN84643.1 - 5.4e-06 25.9 0.0 0.055 12.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KZN84643.1 - 1.2e-05 24.6 0.5 0.0041 16.4 0.1 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 KZN84643.1 - 1.5e-05 24.4 0.1 2.4e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KZN84643.1 - 0.00075 18.9 0.2 1.2 8.4 0.1 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase GIDA PF01134.22 KZN84643.1 - 0.0011 18.1 3.2 0.12 11.4 0.8 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox PF00070.27 KZN84643.1 - 0.01 16.4 1.0 8 7.1 0.2 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KZN84643.1 - 0.076 12.3 0.5 0.18 11.1 0.5 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Ribosomal_60s PF00428.19 KZN84643.1 - 0.19 12.3 3.0 0.44 11.2 3.0 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Histone_HNS PF00816.21 KZN84644.1 - 0.0011 19.7 0.1 0.0027 18.5 0.1 1.7 1 0 0 1 1 1 1 H-NS histone family Podoplanin PF05808.11 KZN84644.1 - 0.078 13.1 0.3 0.078 13.1 0.3 2.1 2 1 0 2 2 2 0 Podoplanin WD40 PF00400.32 KZN84645.1 - 2e-13 50.6 4.7 0.094 13.6 0.3 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN84645.1 - 0.01 16.1 0.2 3.2 8.1 0.0 3.9 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Sin3a_C PF16879.5 KZN84646.1 - 8e-76 255.5 5.5 8e-76 255.5 5.5 3.3 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein PAH PF02671.21 KZN84646.1 - 1.6e-41 140.2 3.0 1.3e-17 63.7 0.0 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KZN84646.1 - 5.5e-39 132.2 0.0 1.8e-38 130.6 0.0 1.9 1 0 0 1 1 1 1 Sin3 family co-repressor Bap31_Bap29_C PF18035.1 KZN84646.1 - 0.11 12.5 1.0 0.62 10.1 1.0 2.3 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF682 PF05081.12 KZN84646.1 - 0.14 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF682) AcetylCoA_hydro PF02550.15 KZN84647.1 - 2.2e-49 168.1 0.0 3.4e-49 167.5 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 KZN84647.1 - 1.2e-39 135.7 0.0 2e-39 135.0 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Glyco_hydro_17 PF00332.18 KZN84649.1 - 0.0043 16.7 0.4 0.011 15.3 0.4 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 LapA_dom PF06305.11 KZN84650.1 - 0.0071 16.1 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain DUF4834 PF16118.5 KZN84650.1 - 0.013 16.5 0.0 0.018 16.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) tRNA_anti-like PF12869.7 KZN84650.1 - 0.016 14.9 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 tRNA_anti-like FAM176 PF14851.6 KZN84650.1 - 0.064 12.9 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 FAM176 family FHIPEP PF00771.20 KZN84650.1 - 0.082 11.4 0.0 0.088 11.3 0.0 1.0 1 0 0 1 1 1 0 FHIPEP family PAP_PilO PF06864.12 KZN84650.1 - 0.12 11.2 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) FixS PF03597.15 KZN84650.1 - 1.8 8.4 10.3 0.51 10.1 7.1 1.7 1 1 1 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type MFS_1 PF07690.16 KZN84652.1 - 1.6e-30 106.2 35.5 1.6e-30 106.2 35.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 KZN84653.1 - 9.6e-23 80.7 45.0 2.9e-15 56.0 23.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KZN84653.1 - 0.0028 16.2 6.9 0.003 16.0 6.7 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UCR_Fe-S_N PF10399.9 KZN84653.1 - 0.29 10.5 5.4 15 5.1 0.0 3.1 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Sugar_tr PF00083.24 KZN84654.1 - 4.9e-75 253.1 22.7 5.9e-75 252.9 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN84654.1 - 7.9e-19 67.8 44.4 3.7e-10 39.3 18.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KZN84654.1 - 0.0026 16.3 17.0 0.0096 14.4 2.2 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Transgly_assoc PF04226.13 KZN84654.1 - 0.064 13.5 5.1 0.86 9.9 0.0 4.4 4 0 0 4 4 4 0 Transglycosylase associated protein DUF4131 PF13567.6 KZN84654.1 - 6.4 6.4 11.8 4 7.1 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Sel1 PF08238.12 KZN84655.1 - 1.1e-17 64.1 4.3 7.7e-06 26.4 0.4 4.3 5 0 0 5 5 5 3 Sel1 repeat TPR_6 PF13174.6 KZN84655.1 - 0.0038 17.8 2.3 0.51 11.1 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Mt_ATP-synt_B PF05405.14 KZN84656.1 - 2.2e-51 173.7 9.2 3e-51 173.3 9.2 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF2526 PF10735.9 KZN84656.1 - 0.028 14.6 2.8 0.12 12.6 1.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2526) V_ATPase_I PF01496.19 KZN84656.1 - 0.84 7.5 7.5 1.1 7.1 7.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CBF PF03914.17 KZN84657.1 - 1.1e-36 126.5 1.7 2.4e-36 125.3 0.4 2.2 2 0 0 2 2 2 1 CBF/Mak21 family MIF4G PF02854.19 KZN84657.1 - 0.023 14.4 0.1 4.6 6.8 0.0 2.7 2 0 0 2 2 2 0 MIF4G domain DPPIV_rep PF18811.1 KZN84657.1 - 0.085 12.8 0.1 0.22 11.5 0.1 1.8 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) low complexity region GPI-anchored PF10342.9 KZN84658.1 - 5.5e-17 62.3 0.3 5.5e-17 62.3 0.3 2.8 1 1 2 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SOG2 PF10428.9 KZN84658.1 - 6.3 5.9 16.4 7.3 5.7 16.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SHE3 PF17078.5 KZN84659.1 - 3.9e-07 30.0 33.2 4.3e-06 26.6 23.6 2.3 1 1 1 2 2 2 2 SWI5-dependent HO expression protein 3 ADIP PF11559.8 KZN84659.1 - 0.0016 18.5 15.5 0.0016 18.5 15.5 3.2 1 1 2 3 3 3 1 Afadin- and alpha -actinin-Binding ZapB PF06005.12 KZN84659.1 - 0.0051 17.2 7.0 0.0051 17.2 7.0 4.0 2 2 1 3 3 3 1 Cell division protein ZapB DUF4061 PF13270.6 KZN84659.1 - 0.0096 16.2 0.9 0.0096 16.2 0.9 3.4 1 1 2 3 3 3 1 Domain of unknown function (DUF4061) Vac_Fusion PF02346.16 KZN84659.1 - 0.3 10.8 5.6 0.77 9.4 0.0 3.7 3 1 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 DUF3037 PF11236.8 KZN84659.1 - 0.77 10.2 7.4 0.97 9.9 0.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) DXP_reductoisom PF02670.16 KZN84659.1 - 5.2 7.8 7.4 8.8 7.1 0.3 2.6 2 1 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase MMS19_C PF12460.8 KZN84663.1 - 7e-126 420.8 23.1 2.5e-124 415.6 12.5 4.1 2 1 0 4 4 4 2 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 KZN84663.1 - 2.5e-95 319.0 2.1 1.7e-92 309.7 0.0 3.7 3 1 0 3 3 3 2 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.6 KZN84663.1 - 2.3e-06 27.9 8.5 1.3 9.5 0.2 6.7 7 0 0 7 7 7 2 HEAT repeats RTP1_C1 PF10363.9 KZN84663.1 - 8.2e-06 26.0 10.0 0.017 15.3 0.0 5.0 6 0 0 6 6 6 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 KZN84663.1 - 0.0098 16.4 13.0 5.6 7.6 0.7 5.9 6 0 0 6 6 6 1 HEAT-like repeat HEAT PF02985.22 KZN84663.1 - 0.014 15.6 13.5 52 4.5 0.3 7.7 8 0 0 8 8 8 0 HEAT repeat WAPL PF07814.13 KZN84663.1 - 0.11 11.3 4.9 0.13 11.0 2.7 2.4 1 1 1 2 2 2 0 Wings apart-like protein regulation of heterochromatin Arm PF00514.23 KZN84663.1 - 0.16 12.1 7.7 1.4 9.0 0.0 4.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Proteasom_PSMB PF10508.9 KZN84663.1 - 0.3 9.6 3.8 0.4 9.1 0.2 2.9 4 0 0 4 4 4 0 Proteasome non-ATPase 26S subunit Fasciclin PF02469.22 KZN84664.1 - 2.5e-08 34.2 0.0 4.4e-08 33.4 0.0 1.4 1 1 0 1 1 1 1 Fasciclin domain EMC3_TMCO1 PF01956.16 KZN84665.1 - 3.8e-45 153.7 0.8 4.9e-45 153.3 0.8 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like SPC25 PF06703.11 KZN84666.1 - 1.1e-49 168.4 0.0 1.2e-49 168.2 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) THF_DHG_CYH PF00763.23 KZN84668.1 - 1.7e-25 89.5 0.1 2.5e-25 89.0 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KZN84668.1 - 1e-11 44.4 0.0 8.6e-10 38.2 0.0 2.8 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ATP-synt_ab PF00006.25 KZN84669.1 - 1.8e-72 243.5 0.0 2.5e-72 243.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KZN84669.1 - 6.3e-48 162.3 0.6 1.1e-47 161.5 0.6 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KZN84669.1 - 3.8e-15 56.2 2.9 9e-15 54.9 2.9 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RbcS PF12338.8 KZN84669.1 - 5.9 7.2 8.5 2.4 8.4 0.2 2.7 2 0 0 2 2 2 0 Ribulose-1,5-bisphosphate carboxylase small subunit DUF962 PF06127.11 KZN84670.1 - 2.1e-17 63.0 2.6 3e-17 62.5 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) SHS2_Rpb7-N PF03876.17 KZN84671.1 - 3.1e-14 53.1 0.0 6e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KZN84671.1 - 2.9e-10 40.3 0.0 4.6e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain Piwi PF02171.17 KZN84673.1 - 8.4e-73 245.2 0.0 1.3e-72 244.6 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KZN84673.1 - 2.8e-18 66.9 0.0 4.9e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 KZN84673.1 - 7.7e-13 48.6 0.0 1.2e-11 44.7 0.0 2.8 2 0 0 2 2 2 1 Argonaute linker 2 domain PAZ PF02170.22 KZN84673.1 - 1.4e-10 41.1 0.0 3.3e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 KZN84673.1 - 4.1e-10 39.2 0.3 1.3e-09 37.6 0.2 2.0 2 0 0 2 2 2 1 Argonaute linker 1 domain ArgoMid PF16487.5 KZN84673.1 - 1e-05 25.7 0.0 2.1e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute Cation_ATPase_C PF00689.21 KZN84674.1 - 5.3e-49 166.4 11.0 5.3e-49 166.4 11.0 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KZN84674.1 - 1.3e-38 132.3 0.1 1.3e-38 132.3 0.1 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KZN84674.1 - 2e-21 75.9 0.0 3.6e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KZN84674.1 - 3.8e-15 56.7 0.0 7e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KZN84674.1 - 7.1e-12 44.8 0.4 2.8e-10 39.8 0.0 2.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KZN84674.1 - 0.00057 19.7 0.0 0.046 13.5 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ferlin_C PF16165.5 KZN84674.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 Ferlin C-terminus LptF_LptG PF03739.14 KZN84674.1 - 0.69 8.7 9.1 0.13 11.1 4.8 1.9 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG DUF3325 PF11804.8 KZN84674.1 - 2.8 8.1 0.0 2.8 8.1 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3325) Chitin_bind_1 PF00187.19 KZN84675.1 - 6.4e-06 26.6 7.6 6.4e-06 26.6 7.6 3.2 2 1 0 2 2 2 1 Chitin recognition protein LysM PF01476.20 KZN84675.1 - 6.6e-05 22.9 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 LysM domain Dicty_REP PF05086.12 KZN84675.1 - 2.1 6.2 6.9 2.8 5.8 6.9 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein HSP20 PF00011.21 KZN84676.1 - 1.9e-18 66.5 0.0 2.7e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KZN84676.1 - 0.00012 21.6 0.0 0.00063 19.2 0.0 2.0 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Inv-AAD PF18785.1 KZN84677.1 - 1.1e-55 187.0 0.1 1.3e-55 186.8 0.1 1.0 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KZN84677.1 - 1.7e-15 56.7 0.1 2.3e-15 56.3 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 KZN84677.1 - 0.00031 20.7 0.0 0.00035 20.5 0.0 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain MafB19-deam PF14437.6 KZN84677.1 - 0.033 13.9 0.1 0.054 13.2 0.1 1.4 1 1 0 1 1 1 0 MafB19-like deaminase NAD1 PF18778.1 KZN84677.1 - 0.13 12.4 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 Retrotran_gag_2 PF14223.6 KZN84678.1 - 1.5e-05 24.7 0.0 2.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 KZN84678.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type CagZ PF09053.10 KZN84678.1 - 0.069 12.8 1.2 0.68 9.5 0.6 2.2 1 1 1 2 2 2 0 CagZ NAD_binding_8 PF13450.6 KZN84680.1 - 9.5e-10 38.6 0.0 1.9e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KZN84680.1 - 1.5e-09 37.7 0.0 2.7e-06 26.9 0.0 3.1 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 KZN84680.1 - 2.3e-06 27.1 0.0 3.5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KZN84680.1 - 1.1e-05 24.7 0.3 3.3e-05 23.2 0.3 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KZN84680.1 - 7.3e-05 22.1 0.0 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KZN84680.1 - 0.00012 21.4 0.0 0.0019 17.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KZN84680.1 - 0.00014 20.7 0.1 0.00022 20.1 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KZN84680.1 - 0.00023 20.5 0.0 0.00041 19.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KZN84680.1 - 0.0033 17.1 0.0 0.0066 16.1 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KZN84680.1 - 0.0035 16.8 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KZN84680.1 - 0.015 14.4 0.1 0.022 13.9 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FA_desaturase PF00487.24 KZN84681.1 - 1.2e-21 77.7 24.6 5e-21 75.7 24.6 2.0 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KZN84681.1 - 0.0028 17.8 0.0 0.0047 17.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) MFS_1 PF07690.16 KZN84682.1 - 1.3e-37 129.6 49.2 1.3e-37 129.6 49.2 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KZN84682.1 - 2.3e-19 69.3 29.8 3.9e-19 68.5 29.8 1.2 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KZN84682.1 - 4.5e-16 58.7 10.1 4.5e-16 58.7 10.1 3.2 3 0 0 3 3 3 1 Sugar (and other) transporter DUF4231 PF14015.6 KZN84682.1 - 0.3 11.6 1.4 1.3 9.5 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Abhydrolase_3 PF07859.13 KZN84683.1 - 2.9e-37 128.6 0.0 4.2e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KZN84683.1 - 0.00022 20.2 0.1 0.0021 17.0 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.21 KZN84683.1 - 0.0021 17.6 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KZN84683.1 - 0.0042 16.9 0.0 0.0064 16.3 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 KZN84683.1 - 0.013 15.1 0.0 0.027 14.0 0.0 1.5 2 0 0 2 2 2 0 Dienelactone hydrolase family AXE1 PF05448.12 KZN84683.1 - 0.014 14.1 0.0 0.02 13.6 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF4064 PF13273.6 KZN84684.1 - 0.19 12.1 8.1 6.8 7.0 0.5 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) zf-LITAF-like PF10601.9 KZN84684.1 - 1 9.6 4.5 2.2 8.6 0.0 3.2 4 0 0 4 4 4 0 LITAF-like zinc ribbon domain DUF1980 PF09323.10 KZN84685.1 - 0.037 13.9 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) PMP1_2 PF08114.11 KZN84685.1 - 0.17 11.6 0.1 0.17 11.6 0.1 2.5 2 0 0 2 2 2 0 ATPase proteolipid family COesterase PF00135.28 KZN84686.1 - 5e-64 217.0 0.0 7.3e-64 216.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KZN84686.1 - 0.00027 20.9 1.6 0.00037 20.4 0.1 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 KZN84686.1 - 0.0062 16.1 0.4 0.16 11.4 0.1 2.2 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 KZN84686.1 - 0.012 16.2 1.4 0.022 15.4 0.1 1.9 1 1 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KZN84686.1 - 0.023 14.2 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KZN84686.1 - 0.025 14.2 0.4 0.093 12.4 0.4 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KZN84686.1 - 0.078 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 GATase PF00117.28 KZN84687.1 - 6.5e-08 32.6 0.0 9.2e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OPT PF03169.15 KZN84688.1 - 5.2e-123 411.8 39.6 6e-123 411.6 39.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4231 PF14015.6 KZN84688.1 - 0.076 13.5 0.2 0.076 13.5 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DUF2207 PF09972.9 KZN84688.1 - 2.4 6.8 4.7 0.5 9.1 0.3 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3425 PF11905.8 KZN84689.1 - 1e-20 73.9 0.2 2e-20 73.0 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KZN84689.1 - 0.27 11.4 4.9 0.44 10.7 4.9 1.3 1 0 0 1 1 1 0 bZIP transcription factor adh_short PF00106.25 KZN84690.1 - 1.6e-31 109.3 0.0 2.2e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN84690.1 - 1.7e-20 73.6 0.0 2.3e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN84690.1 - 0.00012 22.1 0.9 0.0013 18.6 0.3 2.4 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 KZN84690.1 - 0.023 14.2 0.2 0.075 12.5 0.1 1.8 1 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KZN84690.1 - 0.045 12.8 0.1 0.073 12.1 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Abhydrolase_6 PF12697.7 KZN84691.1 - 1.5e-05 25.7 0.0 2.5e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KZN84691.1 - 8.3e-05 22.2 0.0 0.00053 19.6 0.0 2.2 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KZN84691.1 - 0.00031 20.4 0.1 0.00044 19.9 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF1100 PF06500.11 KZN84691.1 - 0.00043 19.2 0.0 0.00058 18.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) AXE1 PF05448.12 KZN84691.1 - 0.0014 17.4 0.1 0.042 12.5 0.1 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 KZN84691.1 - 0.021 14.1 0.0 0.092 12.0 0.0 2.0 1 1 0 1 1 1 0 Serine aminopeptidase, S33 FTCD_C PF04961.12 KZN84691.1 - 0.023 14.5 0.1 0.037 13.8 0.1 1.2 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase HET PF06985.11 KZN84692.1 - 3.5e-05 24.2 0.1 0.0024 18.2 0.0 2.5 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) Ig_C19orf38 PF17737.1 KZN84692.1 - 0.051 13.9 0.0 0.097 13.0 0.0 1.4 1 0 0 1 1 1 0 Ig domain in C19orf38 (HIDE1) Glyco_hydro_3_C PF01915.22 KZN84693.1 - 1.3e-48 165.7 0.0 2e-48 165.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KZN84693.1 - 7.4e-33 114.3 0.0 1.4e-32 113.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KZN84693.1 - 4.2e-23 81.2 0.0 8.5e-23 80.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Isochorismatase PF00857.20 KZN84694.1 - 1.7e-40 139.0 0.2 2e-40 138.8 0.2 1.0 1 0 0 1 1 1 1 Isochorismatase family Catalase PF00199.19 KZN84695.1 - 6.9e-114 380.9 3.3 2.7e-59 201.2 0.2 3.1 1 1 1 2 2 2 2 Catalase Catalase-rel PF06628.12 KZN84695.1 - 8.9e-07 29.0 0.0 3.5e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 Catalase-related immune-responsive GMC_oxred_C PF05199.13 KZN84696.1 - 0.0015 19.1 0.0 0.0017 18.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KZN84697.1 - 4.1e-17 62.3 0.0 1.4e-12 47.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KZN84697.1 - 1.6e-09 37.5 0.2 2.2e-05 23.9 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KZN84697.1 - 4e-07 29.1 0.0 8.3e-05 21.5 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 KZN84697.1 - 3.9e-05 23.4 0.3 0.0041 16.8 0.1 2.4 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KZN84697.1 - 9.7e-05 22.5 0.1 0.00022 21.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KZN84697.1 - 0.00014 21.1 0.2 0.0005 19.3 0.0 2.0 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.22 KZN84697.1 - 0.00017 20.8 0.1 0.0016 17.6 0.0 2.1 1 1 1 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 KZN84697.1 - 0.0014 17.9 0.0 0.0024 17.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KZN84697.1 - 0.0015 18.5 0.1 1.3 8.9 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KZN84697.1 - 0.0037 16.6 0.1 0.0061 15.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KZN84697.1 - 0.0037 16.4 0.0 0.027 13.6 0.0 2.2 2 1 1 3 3 3 1 Lycopene cyclase protein FAD_oxidored PF12831.7 KZN84697.1 - 0.0043 16.4 0.4 0.013 14.9 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KZN84697.1 - 0.019 15.5 0.0 0.05 14.2 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KZN84697.1 - 0.022 14.1 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 KZN84697.1 - 0.035 13.2 0.0 3 6.9 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 KZN84697.1 - 0.038 12.8 0.0 0.065 12.1 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase APH PF01636.23 KZN84699.1 - 1.9e-12 47.6 0.0 4.9e-12 46.3 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 KZN84699.1 - 0.00069 19.0 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KZN84699.1 - 0.0024 17.5 0.0 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 KZN84699.1 - 0.036 12.9 0.0 0.056 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) APH PF01636.23 KZN84700.1 - 1.9e-12 47.6 0.0 6.7e-12 45.8 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KZN84700.1 - 0.001 18.0 0.0 1.1 8.0 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) GXWXG PF14231.6 KZN84702.1 - 1.7e-05 24.8 0.0 84 3.3 0.0 5.7 6 0 0 6 6 6 5 GXWXG protein G-alpha PF00503.20 KZN84705.1 - 4.4e-53 180.7 4.6 9.3e-41 140.1 1.7 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Arf PF00025.21 KZN84705.1 - 5.9e-11 42.1 0.1 1.3e-10 41.0 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KZN84705.1 - 6.2e-06 25.7 0.2 7.7e-06 25.4 0.2 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 KZN84705.1 - 0.0038 16.9 0.1 0.0087 15.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 KZN84705.1 - 0.0068 15.8 0.1 0.014 14.8 0.0 1.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Roc PF08477.13 KZN84705.1 - 0.0075 16.5 0.5 0.034 14.4 0.5 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_21 PF13304.6 KZN84705.1 - 0.016 15.1 0.1 0.026 14.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NB-ARC PF00931.22 KZN84705.1 - 0.018 14.2 0.5 0.032 13.4 0.5 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 KZN84705.1 - 0.022 14.9 0.0 0.071 13.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KZN84705.1 - 0.025 15.1 0.5 0.042 14.4 0.5 1.5 1 1 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 KZN84705.1 - 0.029 14.5 0.0 0.069 13.2 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KZN84705.1 - 0.034 13.5 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DAP3 PF10236.9 KZN84705.1 - 0.038 13.2 0.4 0.068 12.3 0.4 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF815 PF05673.13 KZN84705.1 - 0.05 12.8 0.0 0.09 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TniB PF05621.11 KZN84705.1 - 0.051 13.0 0.2 0.16 11.4 0.2 1.9 1 1 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 KZN84705.1 - 0.053 13.3 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KZN84705.1 - 0.054 13.0 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KZN84705.1 - 0.059 13.3 1.6 2.4 8.0 0.6 2.8 1 1 1 3 3 3 0 RsgA GTPase AAA_25 PF13481.6 KZN84705.1 - 0.068 12.7 0.0 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KZN84705.1 - 0.094 12.0 0.1 0.19 10.9 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin ATP_bind_1 PF03029.17 KZN84705.1 - 0.16 11.7 0.6 8.6 6.1 0.1 2.4 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KZN84705.1 - 0.24 11.8 0.6 0.46 10.9 0.6 1.7 1 1 0 1 1 1 0 AAA ATPase domain NYN PF01936.18 KZN84706.1 - 8.9e-32 110.6 0.0 1.3e-31 110.1 0.0 1.2 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.7 KZN84706.1 - 2.1e-14 53.1 0.0 5.9e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 OST-HTH/LOTUS domain Fe-S_assembly PF04384.13 KZN84706.1 - 0.012 16.2 0.0 0.024 15.2 0.0 1.4 1 0 0 1 1 1 0 Iron-sulphur cluster assembly MgtE PF01769.16 KZN84707.1 - 0.0031 17.9 2.0 1.1 9.6 0.1 2.3 2 0 0 2 2 2 2 Divalent cation transporter Frag1 PF10277.9 KZN84707.1 - 0.0042 16.6 1.4 0.047 13.2 1.4 2.1 1 1 0 1 1 1 1 Frag1/DRAM/Sfk1 family SLC35F PF06027.12 KZN84707.1 - 0.021 14.4 0.1 0.039 13.4 0.1 1.4 1 0 0 1 1 1 0 Solute carrier family 35 NrsF PF06532.11 KZN84707.1 - 0.29 10.8 6.2 0.08 12.7 2.1 2.0 2 0 0 2 2 2 0 Negative regulator of sigma F Acyl_transf_3 PF01757.22 KZN84707.1 - 0.83 8.6 5.0 0.59 9.1 1.0 2.0 2 0 0 2 2 2 0 Acyltransferase family BIR PF00653.21 KZN84708.1 - 3.3e-05 24.5 0.1 6e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain TPR_10 PF13374.6 KZN84709.1 - 5.6e-83 270.9 12.2 3.3e-13 49.1 0.0 8.0 7 1 1 8 8 8 8 Tetratricopeptide repeat TPR_12 PF13424.6 KZN84709.1 - 1.6e-75 249.4 24.2 3.2e-16 59.4 0.2 6.1 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 KZN84709.1 - 3.1e-29 98.8 11.3 0.00099 19.0 0.1 8.2 7 1 1 8 8 8 7 Tetratricopeptide repeat TPR_4 PF07721.14 KZN84709.1 - 5.3e-23 79.2 0.9 0.03 14.9 0.0 6.8 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 KZN84709.1 - 2.7e-20 71.3 7.8 0.087 12.7 0.0 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 KZN84709.1 - 9.5e-20 69.1 6.7 0.23 11.7 0.0 8.0 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.6 KZN84709.1 - 1.2e-19 69.2 10.2 0.056 13.8 0.0 8.1 7 1 1 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.6 KZN84709.1 - 8.9e-17 61.4 8.3 0.1 13.1 0.0 7.2 3 1 5 8 8 8 5 Tetratricopeptide repeat TPR_MalT PF17874.1 KZN84709.1 - 5.7e-14 52.2 11.6 2.2e-11 43.7 5.1 3.0 1 1 2 3 3 3 3 MalT-like TPR region TPR_16 PF13432.6 KZN84709.1 - 1.4e-13 51.2 2.0 1.1 9.9 0.0 7.0 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KZN84709.1 - 1e-12 47.2 6.3 0.22 11.8 0.1 7.7 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 KZN84709.1 - 5.1e-08 33.1 9.0 15 6.7 0.1 7.5 7 1 1 8 8 7 0 Tetratricopeptide repeat PPR PF01535.20 KZN84709.1 - 4.5e-07 29.7 0.3 21 5.7 0.0 7.0 6 1 1 7 7 7 0 PPR repeat TPR_20 PF14561.6 KZN84709.1 - 1.1e-06 28.8 7.7 8.7 6.8 0.0 6.5 1 1 5 7 7 7 0 Tetratricopeptide repeat SLT_2 PF13406.6 KZN84709.1 - 2.8e-05 23.5 2.2 0.23 10.7 0.1 3.7 1 1 3 4 4 4 2 Transglycosylase SLT domain TPR_3 PF07720.12 KZN84709.1 - 7e-05 22.7 0.0 17 5.5 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3157 PF11355.8 KZN84709.1 - 0.00014 21.6 2.8 0.46 10.1 0.1 3.7 3 1 1 4 4 4 1 Protein of unknown function (DUF3157) Imm49 PF15575.6 KZN84709.1 - 0.00021 21.1 3.7 0.34 10.6 1.4 2.7 1 1 2 3 3 3 2 Immunity protein 49 TPR_5 PF12688.7 KZN84709.1 - 0.00026 21.2 3.7 6.6 7.0 0.2 4.5 2 1 2 5 5 5 0 Tetratrico peptide repeat ANAPC3 PF12895.7 KZN84709.1 - 0.0014 18.8 2.8 13 6.1 0.1 5.4 2 1 4 6 6 5 0 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.6 KZN84709.1 - 0.0029 17.1 0.7 0.037 13.4 0.4 2.2 1 1 1 2 2 2 1 Soluble NSF attachment protein, SNAP DUF1897 PF09005.10 KZN84709.1 - 0.0032 16.9 7.2 2.5 7.7 0.3 4.7 5 0 0 5 5 5 2 Domain of unknown function (DUF1897) PPR_1 PF12854.7 KZN84709.1 - 0.01 15.5 2.1 53 3.6 0.0 5.0 5 0 0 5 5 5 0 PPR repeat TPR_11 PF13414.6 KZN84709.1 - 0.011 15.3 9.6 7.8 6.3 0.0 6.5 7 0 0 7 7 7 0 TPR repeat RPN6_N PF18055.1 KZN84709.1 - 0.012 16.0 3.5 5.2 7.4 0.1 3.7 3 1 0 4 4 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain DUF3662 PF12401.8 KZN84709.1 - 0.015 15.7 1.7 20 5.6 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2662) Spore_YpjB PF09577.10 KZN84709.1 - 0.019 14.8 2.5 4.4 7.0 0.1 3.8 3 2 1 4 4 4 0 Sporulation protein YpjB (SpoYpjB) PPR_2 PF13041.6 KZN84709.1 - 0.022 14.9 0.3 58 4.0 0.0 4.9 6 0 0 6 6 6 0 PPR repeat family PNPase PF03726.14 KZN84709.1 - 0.05 14.1 0.6 22 5.6 0.0 4.0 3 2 2 5 5 4 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain TPR_6 PF13174.6 KZN84709.1 - 0.055 14.1 12.2 82 4.2 0.0 7.7 8 1 0 8 8 7 0 Tetratricopeptide repeat 4HBT PF03061.22 KZN84709.1 - 0.08 13.3 0.0 14 6.1 0.0 3.6 4 1 0 4 4 4 0 Thioesterase superfamily YqaH PF17448.2 KZN84709.1 - 0.16 12.3 0.0 4 7.8 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized YqaH-like COesterase PF00135.28 KZN84710.1 - 1.7e-78 264.8 0.1 2.4e-78 264.3 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KZN84710.1 - 8.7e-07 29.0 0.5 4.3e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KZN84710.1 - 0.045 12.6 0.0 0.21 10.4 0.0 1.9 2 0 0 2 2 2 0 Steryl acetyl hydrolase PLAC8 PF04749.17 KZN84711.1 - 1.2e-23 84.0 8.0 1.5e-23 83.7 8.0 1.1 1 0 0 1 1 1 1 PLAC8 family WD40 PF00400.32 KZN84712.1 - 9.8e-121 390.2 32.4 2.3e-11 44.1 0.0 12.9 12 1 0 12 12 12 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN84712.1 - 1.2e-47 160.1 0.3 0.00026 21.2 0.0 12.8 3 1 11 14 14 12 10 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KZN84712.1 - 1.5e-17 63.5 0.9 0.48 9.3 0.0 9.6 1 1 8 10 10 10 5 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KZN84712.1 - 5.9e-12 45.2 2.5 10 6.2 0.0 9.2 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat IKI3 PF04762.12 KZN84712.1 - 3.1e-10 38.8 0.8 0.00044 18.4 0.1 3.9 1 1 1 4 4 4 2 IKI3 family NACHT PF05729.12 KZN84712.1 - 4.6e-10 39.7 0.6 1.4e-09 38.0 0.0 2.2 2 0 0 2 2 1 1 NACHT domain WD40_like PF17005.5 KZN84712.1 - 2.6e-09 36.9 0.0 0.98 8.7 0.0 6.6 1 1 6 8 8 8 3 WD40-like domain DUF642 PF04862.12 KZN84712.1 - 3.1e-09 36.8 0.7 1.5 8.6 0.0 5.9 2 1 3 6 6 6 2 Protein of unknown function (DUF642) eIF2A PF08662.11 KZN84712.1 - 6.7e-08 32.6 0.0 0.048 13.5 0.0 4.2 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.9 KZN84712.1 - 1.1e-07 31.4 12.1 3.5 7.4 0.0 8.5 9 0 0 9 9 8 2 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.16 KZN84712.1 - 2.1e-07 29.8 0.4 0.00067 18.3 0.0 4.5 1 1 3 5 5 5 1 Cytochrome D1 heme domain Frtz PF11768.8 KZN84712.1 - 1.3e-06 27.1 0.0 3.2 5.9 0.0 5.2 2 1 4 6 6 6 2 WD repeat-containing and planar cell polarity effector protein Fritz AAA_16 PF13191.6 KZN84712.1 - 1.5e-06 28.7 0.1 1.5e-06 28.7 0.1 2.5 3 0 0 3 3 2 1 AAA ATPase domain Helo_like_N PF17111.5 KZN84712.1 - 0.00039 19.9 0.1 0.0011 18.4 0.1 1.8 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Nbas_N PF15492.6 KZN84712.1 - 0.00047 19.6 9.9 16 4.7 0.0 6.9 2 2 4 7 7 7 0 Neuroblastoma-amplified sequence, N terminal APAF1_C PF17908.1 KZN84712.1 - 0.0086 16.1 0.7 0.027 14.5 0.7 1.8 1 0 0 1 1 1 1 APAF-1 helical domain TruB_C PF09142.11 KZN84712.1 - 0.0095 15.7 1.3 1.8e+02 2.0 0.0 6.1 7 0 0 7 7 7 0 tRNA Pseudouridine synthase II, C terminal DUF4784 PF16023.5 KZN84712.1 - 0.013 14.5 0.1 42 2.9 0.0 5.3 4 2 5 9 9 9 0 Domain of unknown function (DUF4784) PALB2_WD40 PF16756.5 KZN84712.1 - 0.013 14.4 4.6 3.4 6.5 0.0 5.0 3 2 3 7 7 7 0 Partner and localizer of BRCA2 WD40 domain AAA PF00004.29 KZN84712.1 - 0.025 15.0 0.4 0.24 11.8 0.0 2.7 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FragX_IP PF05994.11 KZN84712.1 - 0.042 11.9 0.3 0.069 11.2 0.3 1.2 1 0 0 1 1 1 0 Cytoplasmic Fragile-X interacting family AAA_22 PF13401.6 KZN84712.1 - 0.05 13.9 0.2 0.27 11.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KZN84712.1 - 0.067 13.3 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KZN84712.1 - 0.068 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain KAP_NTPase PF07693.14 KZN84712.1 - 0.1 11.8 2.5 1.1 8.4 1.2 2.5 2 1 0 2 2 2 0 KAP family P-loop domain ATPase_2 PF01637.18 KZN84712.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea APS_kinase PF01583.20 KZN84712.1 - 0.12 12.3 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase Peptidase_S9_N PF02897.15 KZN84712.1 - 0.16 10.7 0.4 1.2e+02 1.3 0.0 4.8 4 2 3 7 7 7 0 Prolyl oligopeptidase, N-terminal beta-propeller domain PIF1 PF05970.14 KZN84712.1 - 0.17 11.1 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Mito_carr PF00153.27 KZN84714.1 - 3.7e-65 215.9 1.5 1.3e-22 79.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_42 PF02449.15 KZN84714.1 - 0.23 10.8 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase CPBP PF02517.16 KZN84715.1 - 6e-15 55.4 7.0 6e-15 55.4 7.0 2.5 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Synaptobrevin PF00957.21 KZN84716.1 - 0.036 13.9 2.1 0.065 13.0 2.1 1.3 1 0 0 1 1 1 0 Synaptobrevin MBOAT PF03062.19 KZN84717.1 - 6e-54 183.7 10.7 1.7e-53 182.2 10.7 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF3961 PF13106.6 KZN84717.1 - 0.053 13.2 1.2 0.14 11.8 1.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) Ycf4 PF02392.16 KZN84717.1 - 0.16 11.5 2.2 0.18 11.4 0.2 1.9 2 0 0 2 2 2 0 Ycf4 Sec1 PF00995.23 KZN84718.1 - 3.1e-133 446.0 0.0 3.7e-133 445.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Glyco_tran_WecB PF03808.13 KZN84718.1 - 0.058 13.3 0.0 0.82 9.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family adh_short PF00106.25 KZN84719.1 - 8.3e-33 113.5 0.0 1.1e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN84719.1 - 2.8e-21 76.2 0.0 3.5e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN84719.1 - 6.1e-11 42.6 0.0 9.2e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KZN84719.1 - 1.5e-06 27.8 0.1 3.6e-06 26.6 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KZN84719.1 - 0.00074 18.7 0.0 0.00097 18.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KZN84719.1 - 0.0013 17.9 0.0 0.0017 17.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DapB_N PF01113.20 KZN84719.1 - 0.01 16.0 0.0 0.025 14.7 0.0 1.6 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.6 KZN84719.1 - 0.014 15.3 0.0 0.03 14.2 0.0 1.5 2 0 0 2 2 2 0 NAD(P)H-binding NmrA PF05368.13 KZN84719.1 - 0.015 14.9 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.19 KZN84719.1 - 0.036 13.1 0.0 0.053 12.5 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KZN84719.1 - 0.13 11.4 0.0 14 4.8 0.0 2.3 2 0 0 2 2 2 0 Male sterility protein HNH_2 PF13391.6 KZN84720.1 - 0.00014 21.9 0.0 0.00052 20.1 0.0 2.0 2 0 0 2 2 2 1 HNH endonuclease Microcephalin PF12258.8 KZN84720.1 - 0.012 14.9 0.5 0.017 14.4 0.5 1.2 1 0 0 1 1 1 0 Microcephalin protein ALIX_LYPXL_bnd PF13949.6 KZN84720.1 - 0.062 12.6 3.9 0.097 11.9 3.9 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV CENP-F_leu_zip PF10473.9 KZN84720.1 - 0.14 12.2 1.9 0.24 11.4 1.9 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4844 PF16133.5 KZN84720.1 - 0.15 12.6 1.5 1.4 9.5 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4844) Wyosine_form PF08608.12 KZN84721.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Wyosine base formation FMO-like PF00743.19 KZN84722.1 - 4.4e-24 84.8 0.1 1.2e-16 60.2 0.0 3.0 3 1 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KZN84722.1 - 9e-23 81.0 0.0 9.4e-21 74.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KZN84722.1 - 1.2e-15 57.5 0.1 2e-12 47.0 0.0 2.9 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KZN84722.1 - 9.5e-09 35.7 0.6 0.0045 17.5 0.1 3.8 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KZN84722.1 - 1.7e-08 34.1 0.1 0.0018 17.6 0.1 3.2 3 0 0 3 3 3 2 FAD binding domain K_oxygenase PF13434.6 KZN84722.1 - 1.7e-07 30.7 0.2 9e-06 25.1 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KZN84722.1 - 9.2e-07 29.0 0.0 0.0038 17.4 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 KZN84722.1 - 3.7e-05 23.2 0.0 0.05 13.0 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 KZN84722.1 - 5.9e-05 22.6 0.0 0.28 10.5 0.0 3.3 4 0 0 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.17 KZN84722.1 - 0.0004 19.7 0.0 0.71 9.1 0.0 2.2 2 0 0 2 2 2 2 Thi4 family DAO PF01266.24 KZN84722.1 - 0.00044 19.9 0.9 0.54 9.8 0.2 3.5 2 2 0 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.22 KZN84722.1 - 0.0015 17.7 0.3 0.2 10.7 0.0 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.14 KZN84722.1 - 0.0041 15.9 0.1 0.57 8.8 0.1 2.9 3 0 0 3 3 3 1 HI0933-like protein Lycopene_cycl PF05834.12 KZN84722.1 - 0.0053 15.8 0.0 0.041 12.9 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KZN84722.1 - 0.0059 16.6 0.8 20 5.2 0.2 3.4 2 1 1 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KZN84722.1 - 0.17 10.9 0.2 2.3 7.2 0.1 2.5 2 1 0 2 2 2 0 FAD binding domain GFO_IDH_MocA PF01408.22 KZN84723.1 - 4.9e-18 66.1 0.0 1.8e-17 64.2 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KZN84723.1 - 5.6e-07 29.6 0.0 9.9e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KZN84723.1 - 0.0036 17.9 0.0 0.007 17.0 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 KZN84723.1 - 0.072 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Sugar_tr PF00083.24 KZN84724.1 - 8.2e-113 377.6 22.2 9.8e-113 377.4 22.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN84724.1 - 7.1e-24 84.4 65.6 3.4e-18 65.7 38.1 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KZN84724.1 - 2.7e-07 29.4 14.1 4.4e-05 22.1 5.9 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) UNC-93 PF05978.16 KZN84724.1 - 0.0053 16.5 3.0 0.0053 16.5 3.0 3.2 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 tRNA-synt_1 PF00133.22 KZN84725.1 - 1.9e-53 181.7 0.0 2e-34 118.9 0.2 6.0 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 KZN84725.1 - 6.2e-39 133.4 0.0 9.4e-39 132.8 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 KZN84725.1 - 3.5e-27 95.2 0.0 4.5e-20 71.8 0.0 4.3 3 1 1 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KZN84725.1 - 1.8e-10 40.9 0.0 4.2e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.19 KZN84725.1 - 0.012 14.6 0.0 0.023 13.6 0.0 1.4 2 0 0 2 2 2 0 tRNA synthetases class I (R) Suc_Fer-like PF06999.12 KZN84726.1 - 4.1e-59 199.7 0.0 4.9e-59 199.5 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Sema PF01403.19 KZN84726.1 - 0.12 11.1 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Sema domain 2-Hacid_dh_C PF02826.19 KZN84727.1 - 3.1e-51 173.3 0.0 5.6e-51 172.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KZN84727.1 - 3.5e-16 59.1 0.0 4.4e-16 58.8 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KZN84727.1 - 0.00058 20.1 0.0 0.0016 18.6 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase FH2 PF02181.23 KZN84729.1 - 1.3e-89 300.9 1.8 1.3e-89 300.9 1.8 1.8 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 KZN84729.1 - 1.8e-68 229.8 1.0 5e-68 228.4 0.0 2.3 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KZN84729.1 - 9.1e-52 175.5 1.4 5.3e-51 173.0 0.1 2.7 2 1 1 3 3 3 1 Diaphanous FH3 Domain TrmE_N PF10396.9 KZN84730.1 - 6.6e-37 126.3 0.0 1.4e-36 125.3 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 KZN84730.1 - 1.6e-29 103.5 0.0 5e-29 102.0 0.0 1.8 1 1 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 KZN84730.1 - 2.5e-17 63.0 0.0 4.1e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KZN84730.1 - 5.6e-05 22.7 0.1 0.00026 20.5 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KZN84730.1 - 0.00018 21.6 0.0 0.00029 21.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GTP_EFTU PF00009.27 KZN84730.1 - 0.00023 20.8 0.0 0.017 14.7 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 KZN84730.1 - 0.0019 18.0 0.1 0.0053 16.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KZN84730.1 - 0.087 12.7 0.2 0.41 10.5 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase Roc PF08477.13 KZN84730.1 - 0.13 12.5 0.1 0.4 10.9 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase HscB_4_cys PF18256.1 KZN84731.1 - 0.036 13.9 0.6 0.036 13.9 0.6 2.4 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif zf-C2H2_2 PF12756.7 KZN84731.1 - 0.063 13.6 0.3 0.15 12.4 0.3 1.6 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KZN84731.1 - 0.18 12.8 3.6 2.8 9.0 1.0 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_7 PF15269.6 KZN84731.1 - 2.4 8.3 6.7 12 6.1 1.4 2.3 2 0 0 2 2 2 0 Zinc-finger Aminotran_5 PF00266.19 KZN84732.1 - 4e-29 101.7 0.0 1.4e-18 67.0 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V DUF4328 PF14219.6 KZN84732.1 - 0.0043 16.6 0.0 0.016 14.8 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4328) NAD_binding_1 PF00175.21 KZN84733.1 - 1.7e-08 35.1 0.0 0.0048 17.5 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KZN84733.1 - 0.00013 22.3 0.0 0.0004 20.7 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KZN84733.1 - 0.0057 16.8 0.0 0.021 15.0 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain AA_permease_2 PF13520.6 KZN84734.1 - 3.7e-61 207.2 37.3 5.8e-61 206.6 37.3 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN84734.1 - 1.6e-26 93.0 24.1 1.6e-26 93.0 24.1 2.2 2 0 0 2 2 2 1 Amino acid permease NADHdeh_related PF10125.9 KZN84734.1 - 0.69 9.3 11.4 0.023 14.1 4.6 1.9 2 0 0 2 2 2 0 NADH dehydrogenase I, subunit N related protein Glyco_hydro_32N PF00251.20 KZN84735.1 - 2.3e-45 155.5 0.0 3.1e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KZN84735.1 - 5.8e-26 91.4 0.0 9e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.20 KZN84735.1 - 0.007 16.2 1.7 0.13 12.3 0.0 3.1 2 0 0 2 2 2 1 BNR/Asp-box repeat BNR_2 PF13088.6 KZN84735.1 - 0.027 13.8 0.4 0.2 10.9 0.1 2.2 2 1 0 2 2 2 0 BNR repeat-like domain DUF4975 PF16346.5 KZN84735.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4975) Sugar_tr PF00083.24 KZN84736.1 - 1.9e-84 284.2 11.2 2.3e-84 283.9 11.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN84736.1 - 7.7e-24 84.3 31.5 3.4e-21 75.6 12.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 KZN84737.1 - 2.1e-09 37.3 9.5 2.1e-09 37.3 9.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN84737.1 - 1e-07 31.3 1.5 1e-07 31.3 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Amidase PF01425.21 KZN84738.1 - 7.5e-105 351.5 0.0 1e-104 351.1 0.0 1.2 1 0 0 1 1 1 1 Amidase Rep_fac_C PF08542.11 KZN84739.1 - 5.3e-23 81.2 0.0 3e-22 78.8 0.0 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 KZN84739.1 - 2e-11 44.5 0.0 3.3e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KZN84739.1 - 5e-07 29.6 0.0 0.00021 21.1 0.0 3.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 KZN84739.1 - 2.8e-06 27.4 0.0 1.3e-05 25.2 0.0 2.1 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 KZN84739.1 - 2.2e-05 24.9 0.1 0.00019 21.9 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KZN84739.1 - 0.0001 22.1 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KZN84739.1 - 0.00052 20.3 0.2 0.059 13.6 0.2 2.5 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KZN84739.1 - 0.00063 19.6 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DNA_pol3_delta PF06144.13 KZN84739.1 - 0.0019 18.0 0.0 0.003 17.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_3 PF07726.11 KZN84739.1 - 0.0029 17.5 0.0 0.0056 16.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 KZN84739.1 - 0.0055 15.7 0.0 0.01 14.9 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB KTI12 PF08433.10 KZN84739.1 - 0.01 15.3 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Rad17 PF03215.15 KZN84739.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Mg_chelatase PF01078.21 KZN84739.1 - 0.019 14.3 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 KZN84739.1 - 0.024 14.4 0.1 0.04 13.7 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 KZN84739.1 - 0.03 14.7 0.0 0.086 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA C-terminal domain NTPase_1 PF03266.15 KZN84739.1 - 0.03 14.2 0.0 0.071 13.0 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_19 PF13245.6 KZN84739.1 - 0.039 14.3 0.0 0.07 13.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 KZN84739.1 - 0.12 12.2 0.3 2.4 7.9 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_5 PF07728.14 KZN84739.1 - 0.15 12.1 0.2 0.37 10.8 0.1 1.8 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) RGS12_usC PF16612.5 KZN84739.1 - 0.21 12.0 0.0 0.37 11.2 0.0 1.3 1 0 0 1 1 1 0 C-terminal unstructured region of RGS12 Imm49 PF15575.6 KZN84740.1 - 0.0047 16.7 0.0 0.0076 16.0 0.0 1.2 1 0 0 1 1 1 1 Immunity protein 49 DUF410 PF04190.13 KZN84741.1 - 5.1e-88 295.2 0.0 6.1e-88 294.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) RAI1 PF08652.11 KZN84742.1 - 1.5e-28 98.7 0.0 3.3e-28 97.7 0.0 1.6 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease IPPT PF01715.17 KZN84743.1 - 3.2e-60 203.8 0.5 4.9e-60 203.2 0.5 1.2 1 0 0 1 1 1 1 IPP transferase zf-met PF12874.7 KZN84743.1 - 4.2e-06 27.0 2.7 7.3e-06 26.2 2.7 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KZN84743.1 - 8.4e-06 25.9 5.2 1.5e-05 25.2 5.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_33 PF13671.6 KZN84743.1 - 0.00045 20.4 0.2 0.024 14.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain IPT PF01745.16 KZN84743.1 - 0.0017 17.8 0.1 0.0054 16.1 0.0 1.9 2 0 0 2 2 2 1 Isopentenyl transferase AAA_18 PF13238.6 KZN84743.1 - 0.0035 17.9 0.3 0.18 12.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain Cytidylate_kin PF02224.18 KZN84743.1 - 0.02 14.6 0.1 0.052 13.3 0.0 1.8 2 0 0 2 2 2 0 Cytidylate kinase zf-C2H2_2 PF12756.7 KZN84743.1 - 0.026 14.8 2.4 0.065 13.6 2.4 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) AAA_16 PF13191.6 KZN84743.1 - 0.046 14.1 0.0 0.21 12.0 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 KZN84743.1 - 0.05 13.2 0.4 0.29 10.7 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 KZN84743.1 - 0.062 13.5 0.4 0.41 10.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain zf-C2H2_4 PF13894.6 KZN84743.1 - 0.094 13.6 0.5 0.19 12.6 0.5 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger AAA_22 PF13401.6 KZN84743.1 - 0.095 13.0 0.0 0.45 10.8 0.0 2.1 1 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KZN84744.1 - 2.7e-17 63.6 0.1 2.3e-16 60.6 0.1 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KZN84744.1 - 9.3e-11 42.1 3.2 6.3e-05 22.9 0.7 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KZN84744.1 - 0.00075 19.2 0.2 0.0013 18.4 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain PduV-EutP PF10662.9 KZN84744.1 - 0.00089 19.0 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SMC_N PF02463.19 KZN84744.1 - 0.0011 18.4 0.1 0.51 9.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF3584 PF12128.8 KZN84744.1 - 0.0024 15.5 0.1 0.0032 15.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_23 PF13476.6 KZN84744.1 - 0.0083 16.7 0.1 0.013 16.0 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 KZN84744.1 - 0.014 15.1 0.1 0.021 14.6 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 KZN84744.1 - 0.018 14.6 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KZN84744.1 - 0.021 15.1 0.3 0.057 13.7 0.2 1.8 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KZN84744.1 - 0.021 14.7 0.1 0.036 14.0 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KZN84744.1 - 0.023 15.1 0.7 0.047 14.1 0.7 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_13 PF13166.6 KZN84744.1 - 0.096 11.3 0.1 0.13 10.9 0.1 1.1 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KZN84744.1 - 0.1 12.8 0.1 0.33 11.2 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 KZN84744.1 - 0.13 11.8 0.1 0.22 11.1 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Arf PF00025.21 KZN84744.1 - 0.14 11.6 0.0 0.35 10.3 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_22 PF13401.6 KZN84744.1 - 0.15 12.4 0.8 0.39 11.0 0.8 1.9 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KZN84744.1 - 0.18 11.5 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KZN84744.1 - 0.2 12.1 0.2 1 9.8 0.2 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KZN84744.1 - 0.23 11.4 0.6 1.2 9.1 0.2 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) WD40 PF00400.32 KZN84745.1 - 1.7e-32 110.9 24.9 0.00032 21.4 0.1 11.7 12 0 0 12 12 12 8 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KZN84745.1 - 7.8e-08 31.6 1.0 0.23 10.4 0.1 4.4 3 1 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KZN84745.1 - 1.9e-05 24.9 9.9 3.7 7.9 0.0 7.9 6 2 3 9 9 9 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KZN84745.1 - 0.00011 22.2 0.2 2.2 8.4 0.0 5.4 6 0 0 6 6 6 1 Ciliary BBSome complex subunit 2, middle region DUF4596 PF15363.6 KZN84745.1 - 0.092 13.0 0.7 0.39 11.0 0.7 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) DUF4165 PF13752.6 KZN84745.1 - 0.17 11.9 1.4 0.59 10.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4165) Urm1 PF09138.11 KZN84746.1 - 2e-35 121.0 0.1 2.3e-35 120.9 0.1 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 KZN84746.1 - 0.00087 19.9 0.0 0.0011 19.6 0.0 1.2 1 0 0 1 1 1 1 ThiS family 6PF2K PF01591.18 KZN84747.1 - 5.4e-63 212.3 0.1 8e-63 211.7 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KZN84747.1 - 1.5e-19 70.5 0.7 6.5e-19 68.4 0.7 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KZN84747.1 - 0.021 15.0 0.0 0.052 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 KZN84747.1 - 0.077 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 APS_kinase PF01583.20 KZN84747.1 - 0.13 12.1 0.0 4.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase Porin_3 PF01459.22 KZN84748.1 - 2.4e-81 273.2 0.1 2.7e-81 273.0 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.10 KZN84748.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term Pkinase PF00069.25 KZN84749.1 - 1.8e-66 224.2 0.0 2.1e-66 224.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN84749.1 - 6.5e-25 87.9 0.0 7.9e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KZN84749.1 - 7.6e-06 25.4 0.0 3.4e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KZN84749.1 - 0.0012 18.9 0.2 0.02 14.8 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KZN84749.1 - 0.18 11.1 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MIF4G_like PF09088.11 KZN84750.1 - 1.3e-89 299.0 0.2 2e-89 298.4 0.2 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 KZN84750.1 - 1.3e-75 254.3 0.0 2.3e-75 253.5 0.0 1.4 1 0 0 1 1 1 1 MIF4G like DUF2326 PF10088.9 KZN84750.1 - 0.023 14.4 0.3 0.25 11.1 0.1 2.6 3 0 0 3 3 3 0 Uncharacterised protein conserved in bacteria (DUF2326) AAA_30 PF13604.6 KZN84750.1 - 0.14 11.8 0.0 1.2 8.8 0.0 2.4 1 1 1 2 2 2 0 AAA domain zf-C2H2 PF00096.26 KZN84751.1 - 5.8e-19 67.4 21.5 0.00017 21.8 0.7 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KZN84751.1 - 3.7e-13 49.2 23.7 1.9e-08 34.3 2.3 4.8 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KZN84751.1 - 5.5e-11 42.3 19.2 0.011 16.5 0.9 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KZN84751.1 - 2e-05 24.8 5.9 0.00065 19.9 3.2 3.2 1 1 2 3 3 3 1 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 KZN84751.1 - 0.00013 22.2 4.3 0.065 13.4 0.1 3.3 2 1 1 3 3 3 2 Aberrant zinc-finger zf-met PF12874.7 KZN84751.1 - 0.00096 19.5 8.5 0.066 13.6 0.4 4.6 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-DNA_Pol PF08996.10 KZN84751.1 - 0.12 12.2 5.3 1.3 8.8 1.4 2.4 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger zf-C2H2_6 PF13912.6 KZN84751.1 - 2 8.5 16.8 5.2 7.2 0.6 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger WD40 PF00400.32 KZN84752.1 - 4.9e-63 207.6 10.5 2.5e-09 37.6 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN84752.1 - 5.3e-21 74.7 0.0 0.00064 20.0 0.0 6.5 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 KZN84752.1 - 1.6e-18 66.8 10.0 2.7e-18 66.0 10.0 1.4 1 0 0 1 1 1 1 Tup N-terminal WD40_like PF17005.5 KZN84752.1 - 7.2e-07 28.8 0.0 0.34 10.2 0.0 4.3 4 1 2 6 6 6 2 WD40-like domain Ge1_WD40 PF16529.5 KZN84752.1 - 9e-07 28.1 0.1 0.21 10.5 0.0 4.9 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KZN84752.1 - 4.3e-05 22.2 0.3 0.00044 18.9 0.2 2.4 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.8 KZN84752.1 - 6.3e-05 21.8 0.1 0.3 9.7 0.0 3.2 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 KZN84752.1 - 0.041 13.2 0.0 6.1 6.1 0.0 2.9 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KZN84752.1 - 0.067 13.1 0.0 12 6.0 0.0 3.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat UPF0242 PF06785.11 KZN84752.1 - 0.69 10.0 6.7 1.1 9.4 6.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TPX2 PF06886.11 KZN84752.1 - 0.79 10.0 6.0 1.6 9.0 6.0 1.5 1 1 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) FA_hydroxylase PF04116.13 KZN84753.1 - 4.4e-24 85.3 15.3 4.4e-24 85.3 15.3 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MTS PF05175.14 KZN84754.1 - 2.1e-09 37.2 0.0 1e-05 25.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.6 KZN84754.1 - 2.4e-06 27.4 0.0 4.1e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN84754.1 - 7.6e-06 26.6 0.0 1.5e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KZN84754.1 - 0.00051 19.5 0.0 0.00071 19.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KZN84754.1 - 0.0011 18.3 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family AviRa PF11599.8 KZN84754.1 - 0.0011 18.4 0.0 0.0037 16.8 0.0 1.9 1 1 0 1 1 1 1 RRNA methyltransferase AviRa Methyltransf_23 PF13489.6 KZN84754.1 - 0.0068 16.3 0.0 0.013 15.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN84754.1 - 0.022 15.5 0.0 0.046 14.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_10 PF05971.12 KZN84754.1 - 0.032 13.6 0.0 0.094 12.0 0.0 1.6 2 0 0 2 2 2 0 RNA methyltransferase Methyltransf_11 PF08241.12 KZN84754.1 - 0.082 13.6 0.0 0.15 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 KZN84754.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Asp PF00026.23 KZN84755.1 - 3.1e-70 237.1 8.5 3.8e-70 236.8 8.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KZN84755.1 - 2.5e-13 50.6 5.1 8.5e-12 45.7 5.1 2.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KZN84755.1 - 9.7e-07 29.3 0.2 0.29 11.8 0.0 3.7 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 KZN84755.1 - 0.003 18.1 0.0 9.1 6.9 0.0 3.9 3 2 0 3 3 3 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KZN84755.1 - 0.021 14.6 0.1 0.35 10.6 0.0 2.6 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal tRNA-synt_1b PF00579.25 KZN84756.1 - 1.6e-75 254.2 0.0 2e-75 253.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Ribosomal_S10 PF00338.22 KZN84757.1 - 5.6e-28 97.0 0.0 1.2e-27 96.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DAHP_synth_1 PF00793.20 KZN84757.1 - 0.15 10.9 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 DAHP synthetase I family Nucleo_P87 PF07267.11 KZN84757.1 - 0.29 9.9 3.8 0.39 9.5 3.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PNP_UDP_1 PF01048.20 KZN84758.1 - 1.3e-49 168.6 0.1 1.9e-49 168.0 0.1 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Fcf2 PF08698.11 KZN84759.1 - 1.4e-36 124.7 2.3 1.7e-36 124.5 0.7 1.9 1 1 1 2 2 2 1 Fcf2 pre-rRNA processing CBFD_NFYB_HMF PF00808.23 KZN84760.1 - 7e-19 67.9 0.6 1.2e-18 67.2 0.6 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KZN84760.1 - 7.4e-16 58.7 0.1 1.2e-15 58.0 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KZN84760.1 - 0.053 13.8 0.0 0.088 13.1 0.0 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Sec15 PF04091.12 KZN84761.1 - 2.6e-107 358.9 1.2 5.3e-107 357.9 1.2 1.6 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.14 KZN84761.1 - 0.00023 21.1 0.6 0.00023 21.1 0.6 2.7 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain COG2 PF06148.11 KZN84761.1 - 0.0012 18.9 1.4 0.0012 18.9 1.4 2.9 3 1 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec5 PF15469.6 KZN84761.1 - 0.0023 17.8 4.6 0.039 13.8 1.9 3.1 3 0 0 3 3 3 1 Exocyst complex component Sec5 COG5 PF10392.9 KZN84761.1 - 0.004 17.3 4.2 0.013 15.7 2.4 2.7 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Mre11_DNA_bind PF04152.14 KZN84761.1 - 0.021 15.1 0.9 0.12 12.6 0.0 2.6 2 0 0 2 2 2 0 Mre11 DNA-binding presumed domain DUF3510 PF12022.8 KZN84761.1 - 0.033 14.6 3.2 4.5 7.7 0.0 3.6 2 2 1 4 4 4 0 Domain of unknown function (DUF3510) Vps51 PF08700.11 KZN84761.1 - 0.047 13.8 1.5 0.26 11.4 0.2 2.8 2 0 0 2 2 2 0 Vps51/Vps67 ApoLp-III PF07464.11 KZN84761.1 - 0.18 11.9 5.9 2.9 8.0 0.3 3.3 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Vps54_N PF10475.9 KZN84761.1 - 0.24 10.6 8.0 0.066 12.5 2.4 2.2 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex RRM_2 PF04059.12 KZN84762.1 - 3.3e-33 113.8 0.1 1e-32 112.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif 2 RRM_1 PF00076.22 KZN84762.1 - 1.6e-06 27.9 0.0 0.02 14.7 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HeH PF12949.7 KZN84762.1 - 0.086 12.6 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 HeH/LEM domain Smg4_UPF3 PF03467.15 KZN84762.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Smg-4/UPF3 family Baculo_E25 PF05274.11 KZN84763.1 - 0.069 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein E25 Phosphodiest PF01663.22 KZN84764.1 - 5.1e-13 49.4 3.0 6.3e-08 32.6 0.4 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KZN84764.1 - 3.9e-06 26.5 0.0 5.1e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Sulfatase DUF2423 PF10338.9 KZN84765.1 - 5e-20 71.4 3.2 5e-20 71.4 3.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2423) PINIT PF14324.6 KZN84766.1 - 1.1e-39 136.1 0.6 2.1e-39 135.2 0.6 1.5 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KZN84766.1 - 2.2e-22 78.5 6.8 3.7e-22 77.8 6.8 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KZN84766.1 - 1.7e-07 31.0 2.8 4.7e-07 29.5 2.8 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 KZN84766.1 - 0.00024 20.7 0.1 0.00058 19.6 0.1 1.6 1 0 0 1 1 1 1 SAP domain Prok-RING_4 PF14447.6 KZN84766.1 - 0.087 12.7 3.7 0.18 11.7 3.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FYVE_2 PF02318.16 KZN84766.1 - 0.15 12.3 1.2 0.25 11.6 1.2 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger TRAPP PF04051.16 KZN84767.1 - 3.1e-46 156.7 0.0 3.7e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PorB PF11565.8 KZN84767.1 - 0.078 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Alpha helical Porin B Ldh_1_N PF00056.23 KZN84768.1 - 3.5e-45 153.6 0.1 5.1e-45 153.0 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KZN84768.1 - 3.5e-44 150.7 0.0 4.8e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 KZN84768.1 - 4.1e-05 22.7 0.0 6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KZN84768.1 - 0.065 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H-binding Ribosomal_L28e PF01778.17 KZN84769.1 - 2.3e-34 118.6 1.1 2.9e-34 118.2 1.1 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF2015 PF09435.10 KZN84770.1 - 6.5e-45 151.6 0.0 7.9e-45 151.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) RRM_1 PF00076.22 KZN84771.1 - 6.7e-34 115.5 0.0 1.1e-15 57.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KZN84771.1 - 3.5e-05 23.4 0.1 0.18 11.4 0.1 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KZN84771.1 - 0.0088 16.1 0.0 0.037 14.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif OB_RNB PF08206.11 KZN84771.1 - 0.0098 15.6 0.1 0.32 10.7 0.1 2.4 2 0 0 2 2 2 1 Ribonuclease B OB domain RRM_occluded PF16842.5 KZN84771.1 - 0.025 14.4 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Cas_Cas2CT1978 PF09707.10 KZN84771.1 - 0.038 14.1 0.0 10 6.3 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) CMV_1a_C PF12503.8 KZN84771.1 - 0.052 13.5 0.1 14 5.8 0.0 2.7 3 0 0 3 3 3 0 Cucumber mosaic virus 1a protein C terminal Limkain-b1 PF11608.8 KZN84771.1 - 0.055 13.5 0.1 0.97 9.6 0.0 2.1 2 0 0 2 2 2 0 Limkain b1 Tom7 PF08038.12 KZN84772.1 - 5.3e-22 77.2 0.3 6.1e-22 77.0 0.3 1.1 1 0 0 1 1 1 1 TOM7 family Mito_carr PF00153.27 KZN84773.1 - 1.6e-39 133.7 0.8 4e-20 71.5 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein SWIRM PF04433.17 KZN84774.1 - 4.7e-12 46.1 0.0 1.1e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain CDC50 PF03381.15 KZN84775.1 - 1.1e-95 320.4 0.0 1.3e-95 320.1 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family YycH PF07435.11 KZN84775.1 - 0.055 12.4 0.0 0.08 11.9 0.0 1.1 1 0 0 1 1 1 0 YycH protein DUF3185 PF11381.8 KZN84775.1 - 2.3 8.3 5.4 0.78 9.8 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Peptidase_M43 PF05572.13 KZN84776.1 - 1.5e-12 47.7 0.3 4.8e-12 46.0 0.3 1.9 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KZN84776.1 - 3.7e-05 24.0 5.1 9.5e-05 22.6 5.1 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KZN84776.1 - 0.012 16.1 0.1 0.029 14.9 0.1 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KZN84776.1 - 0.02 14.8 1.3 0.031 14.2 1.3 1.4 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Benyvirus_P25 PF05744.11 KZN84776.1 - 0.044 13.1 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Benyvirus P25/P26 protein SPT16 PF08644.11 KZN84777.1 - 1.2e-56 191.1 0.0 3e-56 189.8 0.0 1.8 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 KZN84777.1 - 1.1e-55 187.9 0.1 3.9e-55 186.1 0.1 2.1 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 KZN84777.1 - 7.5e-28 97.6 0.0 1.3e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KZN84777.1 - 2.7e-14 53.3 0.2 7.2e-14 52.0 0.0 1.8 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Arc_PepC PF06819.11 KZN84777.1 - 0.036 14.2 0.6 2.9 8.1 0.0 3.4 4 0 0 4 4 4 0 Archaeal Peptidase A24 C-terminal Domain Na_trans_assoc PF06512.13 KZN84777.1 - 0.5 10.6 7.5 2.3 8.5 6.0 2.7 1 1 0 1 1 1 0 Sodium ion transport-associated Mito_carr PF00153.27 KZN84778.1 - 6e-18 64.6 2.6 5.3e-13 48.7 0.1 3.1 3 1 0 3 3 3 2 Mitochondrial carrier protein Sugar_tr PF00083.24 KZN84779.1 - 8.4e-102 341.3 12.2 1.2e-101 340.8 12.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN84779.1 - 1.9e-28 99.4 30.2 2.8e-26 92.3 24.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KZN84779.1 - 4.2e-06 25.6 20.9 1.5e-05 23.8 7.5 2.6 3 0 0 3 3 3 2 MFS/sugar transport protein INSIG PF07281.12 KZN84779.1 - 0.15 11.7 1.7 0.38 10.4 1.7 1.6 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) TB2_DP1_HVA22 PF03134.19 KZN84779.1 - 0.53 10.3 4.1 0.26 11.2 0.9 2.2 2 0 0 2 2 2 0 TB2/DP1, HVA22 family PMT PF02366.18 KZN84780.1 - 8e-88 294.1 13.5 8e-88 294.1 13.5 1.8 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KZN84780.1 - 1.8e-63 213.7 13.0 1.8e-63 213.7 13.0 2.5 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KZN84780.1 - 2.8e-37 128.4 0.5 4.3e-37 127.8 0.5 1.2 1 0 0 1 1 1 1 MIR domain Ras PF00071.22 KZN84781.1 - 1.3e-47 161.4 0.0 4.8e-37 127.1 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KZN84781.1 - 2.4e-28 98.8 0.0 1.7e-17 63.7 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KZN84781.1 - 6.3e-11 42.0 0.0 2.2e-10 40.3 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KZN84781.1 - 2.7e-08 33.6 0.0 6.5e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KZN84781.1 - 0.00033 20.7 0.0 0.0025 17.9 0.0 2.3 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KZN84781.1 - 0.00095 18.6 0.0 0.003 16.9 0.0 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KZN84781.1 - 0.0049 16.8 0.0 0.93 9.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 KZN84781.1 - 0.014 15.1 0.1 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KZN84781.1 - 0.018 15.3 0.2 0.15 12.3 0.2 2.2 1 1 0 1 1 1 0 AAA domain Flu_M1_C PF08289.11 KZN84781.1 - 0.066 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain Choline_transpo PF04515.12 KZN84782.1 - 7.2e-22 78.0 22.6 7.2e-22 78.0 22.6 2.4 2 0 0 2 2 2 2 Plasma-membrane choline transporter Aldo_ket_red PF00248.21 KZN84784.1 - 4.2e-42 144.3 0.3 1.1e-40 139.6 0.3 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family UPF0061 PF02696.14 KZN84785.1 - 1.9e-122 409.4 0.0 2.4e-122 409.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family F-box PF00646.33 KZN84786.1 - 2.1e-06 27.5 0.2 2.1e-06 27.5 0.2 1.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KZN84786.1 - 3.6e-05 23.6 0.1 7.1e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like SAE2 PF08573.10 KZN84787.1 - 4.8e-36 124.3 0.0 4.8e-36 124.3 0.0 3.0 3 1 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus GAS PF13851.6 KZN84787.1 - 0.0094 15.3 4.8 0.02 14.2 4.8 1.5 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF3287 PF11690.8 KZN84787.1 - 0.0096 15.6 1.3 0.033 13.9 1.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3287) DUF2353 PF09789.9 KZN84787.1 - 0.12 11.7 5.3 0.35 10.2 5.3 1.8 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) HlyD_2 PF12700.7 KZN84787.1 - 0.24 10.1 0.3 0.45 9.2 0.1 1.5 2 0 0 2 2 2 0 HlyD family secretion protein bZIP_1 PF00170.21 KZN84787.1 - 1.5 8.9 13.2 14 5.8 0.9 3.9 4 0 0 4 4 4 0 bZIP transcription factor Histone_HNS PF00816.21 KZN84787.1 - 2 9.3 8.7 1.3 9.9 0.9 3.7 3 1 0 3 3 3 0 H-NS histone family Pex16 PF08610.10 KZN84788.1 - 9.6e-139 462.0 0.1 1.1e-138 461.9 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) RNase_HII PF01351.18 KZN84789.1 - 1.4e-47 162.2 0.0 1.9e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII CENP-C_C PF11699.8 KZN84790.1 - 5.3e-37 125.9 0.6 9.6e-37 125.1 0.6 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.6 KZN84790.1 - 2.1e-34 119.2 4.8 2.1e-34 119.2 4.8 3.7 3 1 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 KZN84790.1 - 4.7e-07 29.4 0.0 1.1e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KZN84790.1 - 0.036 13.7 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 Cupin GAGA_bind PF06217.12 KZN84790.1 - 7.5 6.7 13.8 1.4 9.2 0.5 2.8 3 0 0 3 3 3 0 GAGA binding protein-like family CAP_GLY PF01302.25 KZN84791.1 - 1.7e-25 88.8 0.0 2.5e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 KZN84791.1 - 5.2e-14 52.5 0.0 8.6e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 KZN84791.1 - 0.0002 21.0 0.0 0.001 18.8 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family Methyltransf_11 PF08241.12 KZN84792.1 - 6.7e-15 55.5 0.0 1.1e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN84792.1 - 1.2e-11 45.1 0.1 2.4e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN84792.1 - 4.4e-08 33.1 0.0 1.7e-07 31.3 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN84792.1 - 3.3e-06 27.7 0.1 6.2e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN84792.1 - 1.1e-05 25.2 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KZN84792.1 - 0.0089 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.11 KZN84792.1 - 0.024 13.6 0.0 0.08 11.9 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_8 PF05148.15 KZN84792.1 - 0.14 12.0 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Myb_DNA-binding PF00249.31 KZN84793.1 - 3.7e-14 52.6 1.9 9.5e-11 41.7 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KZN84793.1 - 9.8e-06 25.7 3.3 0.011 15.9 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain AGOG PF09171.10 KZN84793.1 - 0.13 11.6 0.1 0.18 11.1 0.1 1.1 1 0 0 1 1 1 0 N-glycosylase/DNA lyase UCH PF00443.29 KZN84794.1 - 5e-19 68.8 0.0 8.6e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KZN84794.1 - 1.5e-08 34.6 0.0 1.5e-06 28.0 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Spore_III_AF PF09581.10 KZN84794.1 - 1.5 8.8 6.6 0.59 10.1 4.0 1.6 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) GRA6 PF05084.13 KZN84794.1 - 2 8.4 11.4 3.7 7.4 11.4 1.4 1 0 0 1 1 1 0 Granule antigen protein (GRA6) MitMem_reg PF13012.6 KZN84795.1 - 2.1e-37 127.9 0.4 3.5e-37 127.3 0.4 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KZN84795.1 - 6.6e-32 110.0 0.0 1.4e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease NARP1 PF12569.8 KZN84795.1 - 0.12 11.3 4.9 0.2 10.5 4.9 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 tRNA_bind_2 PF13725.6 KZN84795.1 - 0.29 10.8 5.0 0.44 10.2 5.0 1.3 1 0 0 1 1 1 0 Possible tRNA binding domain ADK PF00406.22 KZN84796.1 - 1.7e-59 200.3 0.1 2.2e-59 199.9 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KZN84796.1 - 1.7e-23 83.5 0.4 2.6e-23 83.0 0.1 1.4 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 KZN84796.1 - 7.1e-17 61.1 0.0 1.8e-16 59.8 0.0 1.7 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KZN84796.1 - 4.9e-07 30.3 0.0 8.9e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KZN84796.1 - 1.2e-05 25.5 0.0 2.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran_CTD PF16326.5 KZN84796.1 - 0.051 13.8 0.2 0.21 11.8 0.1 2.0 2 0 0 2 2 2 0 ABC transporter C-terminal domain TSC22 PF01166.18 KZN84796.1 - 0.08 13.3 0.2 0.19 12.1 0.2 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family Thymidylate_kin PF02223.17 KZN84796.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase GFO_IDH_MocA PF01408.22 KZN84797.1 - 2e-16 60.9 0.1 2.7e-16 60.4 0.1 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KZN84797.1 - 0.017 15.7 0.1 0.026 15.2 0.1 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain CFIA_Pcf11 PF11526.8 KZN84798.1 - 6.3e-09 36.2 0.4 1.8e-08 34.8 0.4 1.8 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.13 KZN84798.1 - 7.3e-06 26.7 0.0 1.9e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. VHS PF00790.19 KZN84798.1 - 0.13 12.2 0.0 0.36 10.7 0.0 1.7 2 0 0 2 2 2 0 VHS domain zf-ISL3 PF14690.6 KZN84798.1 - 0.19 12.4 1.4 0.27 11.9 0.3 1.8 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf_UBZ PF18439.1 KZN84798.1 - 0.35 10.5 4.6 1.2 8.8 0.6 2.8 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_4 PF13894.6 KZN84798.1 - 0.76 10.8 2.9 37 5.5 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KZN84798.1 - 1.6 8.8 4.9 18 5.3 0.2 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type HOOK PF05622.12 KZN84799.1 - 2.7e-29 101.9 62.4 4.9e-28 97.7 30.2 2.6 2 1 0 2 2 2 2 HOOK protein TPR_MLP1_2 PF07926.12 KZN84799.1 - 0.00034 20.7 88.0 0.013 15.5 6.0 7.1 6 2 1 7 7 7 4 TPR/MLP1/MLP2-like protein KASH_CCD PF14662.6 KZN84799.1 - 0.0045 16.8 82.9 0.098 12.5 21.0 5.7 3 2 2 5 5 5 3 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 KZN84799.1 - 0.0073 15.2 79.4 0.089 11.7 2.2 5.0 4 1 2 6 6 6 4 Spc7 kinetochore protein Spc42p PF11544.8 KZN84799.1 - 0.012 15.6 5.5 0.012 15.6 5.5 6.6 4 1 2 6 6 5 0 Spindle pole body component Spc42p ATG16 PF08614.11 KZN84799.1 - 0.016 15.4 82.9 0.066 13.4 13.9 5.9 4 2 1 5 5 5 0 Autophagy protein 16 (ATG16) DUF1411 PF07199.11 KZN84799.1 - 0.034 13.8 2.2 0.13 11.9 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1411) TACC_C PF05010.14 KZN84799.1 - 0.035 13.9 0.7 0.035 13.9 0.7 5.0 4 1 1 5 5 4 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal HALZ PF02183.18 KZN84799.1 - 0.1 12.9 0.1 0.1 12.9 0.1 8.1 7 2 2 9 9 9 0 Homeobox associated leucine zipper HMMR_N PF15905.5 KZN84799.1 - 0.31 10.5 74.6 0.087 12.3 39.9 3.7 2 2 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal DUF4407 PF14362.6 KZN84799.1 - 1.3 8.3 58.5 0.86 8.9 17.3 4.3 1 1 2 3 3 2 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 KZN84799.1 - 1.6 8.9 55.1 0.12 12.6 7.5 5.5 3 2 2 5 5 5 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 KZN84799.1 - 5.4 7.1 79.8 0.048 13.8 7.4 5.8 4 1 1 5 5 4 0 Uncharacterised protein family (UPF0242) N-terminus Lebercilin PF15619.6 KZN84799.1 - 5.4 6.6 80.8 0.04 13.6 9.2 5.8 4 1 1 5 5 5 0 Ciliary protein causing Leber congenital amaurosis disease Csm1_N PF18504.1 KZN84799.1 - 8.6 6.8 61.8 2 8.8 4.6 8.1 7 1 0 8 8 8 0 Csm1 N-terminal domain Mito_carr PF00153.27 KZN84800.1 - 4.8e-29 100.1 1.7 1.2e-15 57.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Atg8 PF02991.16 KZN84801.1 - 2.7e-51 172.1 0.2 3.2e-51 171.8 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KZN84801.1 - 3e-06 27.5 0.0 3.6e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Coprogen_oxidas PF01218.18 KZN84802.1 - 1.5e-134 447.4 0.0 3e-134 446.4 0.0 1.5 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase Mito_carr PF00153.27 KZN84803.1 - 5.6e-28 96.7 2.2 1.3e-12 47.4 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Citrate_synt PF00285.21 KZN84804.1 - 1.7e-100 336.6 0.0 2.2e-100 336.3 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain CTD_bind PF04818.13 KZN84805.1 - 3.1e-08 34.3 0.0 6.4e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 KZN84805.1 - 1.1e-05 25.1 0.0 2.2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cys_Met_Meta_PP PF01053.20 KZN84806.1 - 4e-149 496.3 0.0 4.5e-149 496.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KZN84806.1 - 2e-10 40.6 0.3 3.2e-10 39.9 0.3 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KZN84806.1 - 4.7e-09 35.7 0.2 7.1e-09 35.1 0.2 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KZN84806.1 - 4e-08 32.8 0.1 6.2e-08 32.2 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KZN84806.1 - 0.00015 21.1 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 KZN84806.1 - 0.00049 18.7 0.0 0.00066 18.3 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase Asparaginase_C PF17763.1 KZN84806.1 - 0.0059 16.8 0.1 0.018 15.3 0.0 1.8 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain GDC-P PF02347.16 KZN84806.1 - 0.15 10.8 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein Sugar_tr PF00083.24 KZN84807.1 - 5.5e-80 269.4 20.5 6.5e-80 269.2 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN84807.1 - 1.1e-19 70.6 41.0 6.6e-13 48.3 17.2 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 KZN84807.1 - 0.029 13.2 9.8 0.0096 14.8 3.9 2.4 2 1 0 2 2 2 0 MFS_1 like family Phage_holin_7_1 PF16081.5 KZN84807.1 - 0.053 13.7 0.7 0.11 12.7 0.7 1.5 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Fungal_trans PF04082.18 KZN84808.1 - 1.5e-07 30.7 0.2 2.6e-07 29.9 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain HLH PF00010.26 KZN84809.1 - 1.4e-11 44.2 2.5 2.4e-11 43.4 2.5 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF1082 PF06449.11 KZN84809.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1082) Septin PF00735.18 KZN84810.1 - 8.3e-13 48.2 0.0 4.7e-12 45.8 0.0 1.9 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KZN84810.1 - 0.00021 21.3 0.0 0.00054 20.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 KZN84810.1 - 0.0024 17.7 0.0 0.004 16.9 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 KZN84810.1 - 0.0036 16.6 0.0 0.0082 15.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.29 KZN84810.1 - 0.0064 16.9 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KZN84810.1 - 0.0073 16.6 0.1 0.015 15.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KZN84810.1 - 0.01 16.2 0.0 0.034 14.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 KZN84810.1 - 0.012 15.8 0.0 0.03 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KZN84810.1 - 0.021 14.2 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KZN84810.1 - 0.037 13.6 0.1 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 KZN84810.1 - 0.046 13.3 0.0 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KZN84810.1 - 0.047 13.6 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 NACHT domain Roc PF08477.13 KZN84810.1 - 0.05 13.8 0.2 0.45 10.7 0.0 2.4 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 KZN84810.1 - 0.062 13.8 0.0 0.16 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 KZN84810.1 - 0.073 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) GAPES3 PF17154.4 KZN84810.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain ABC_tran PF00005.27 KZN84810.1 - 0.12 12.9 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter NTPase_1 PF03266.15 KZN84810.1 - 0.16 11.9 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 KZN84810.1 - 0.16 11.6 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KZN84810.1 - 0.16 12.2 0.1 1.5 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KZN84810.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 KZN84810.1 - 0.18 11.5 0.1 0.52 10.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain Peptidase_M16 PF00675.20 KZN84811.1 - 1.7e-19 70.3 0.0 3.9e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KZN84811.1 - 2.2e-14 53.9 0.0 4.8e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain M16C_assoc PF08367.11 KZN84811.1 - 0.0024 17.0 0.0 0.0046 16.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16C associated DUF530 PF04409.12 KZN84811.1 - 0.068 11.5 0.2 0.11 10.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF530) UBA_2 PF08587.11 KZN84811.1 - 0.2 11.8 0.3 1.1 9.5 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) Bac_DNA_binding PF00216.21 KZN84811.1 - 0.84 9.9 4.1 16 5.8 0.1 2.7 3 0 0 3 3 3 0 Bacterial DNA-binding protein RNA_pol_Rpc82 PF05645.13 KZN84812.1 - 6.6e-27 94.9 0.0 1.2e-22 80.9 0.0 2.4 2 1 0 2 2 2 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 KZN84812.1 - 6.8e-17 61.3 1.5 2.2e-09 37.3 0.1 3.8 3 0 0 3 3 3 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 KZN84812.1 - 0.00077 19.3 0.3 0.0082 16.0 0.0 2.5 2 1 1 3 3 3 1 TFIIE alpha subunit MARVEL PF01284.23 KZN84813.1 - 2.9e-21 76.0 15.8 3.7e-21 75.7 15.8 1.0 1 0 0 1 1 1 1 Membrane-associating domain AA_permease PF00324.21 KZN84814.1 - 1.8e-135 452.2 48.0 2.2e-135 451.9 48.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KZN84814.1 - 5.9e-32 111.0 52.9 7.2e-32 110.8 52.9 1.1 1 0 0 1 1 1 1 Amino acid permease AMP-binding PF00501.28 KZN84815.1 - 5.4e-85 285.5 0.0 6.5e-85 285.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Tugs PF17840.1 KZN84815.1 - 0.046 13.9 0.1 0.1 12.8 0.1 1.6 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain GST_N_3 PF13417.6 KZN84816.1 - 1.3e-11 44.8 0.1 3.4e-11 43.4 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KZN84816.1 - 2.6e-10 40.4 0.0 4.5e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KZN84816.1 - 7.5e-08 32.3 0.0 1.5e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KZN84816.1 - 0.018 15.4 0.0 0.037 14.4 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Fructosamin_kin PF03881.14 KZN84817.1 - 3e-29 102.1 0.0 3.9e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KZN84817.1 - 0.032 14.1 0.0 0.065 13.1 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family NACHT PF05729.12 KZN84818.1 - 1.6e-06 28.1 0.1 3.8e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 NACHT domain PGAP1 PF07819.13 KZN84818.1 - 5.4e-06 26.3 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 KZN84818.1 - 7.5e-05 22.3 0.2 0.00064 19.3 0.0 2.5 3 0 0 3 3 3 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KZN84818.1 - 0.00036 21.2 0.0 0.0008 20.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_16 PF13191.6 KZN84818.1 - 0.0085 16.5 0.0 0.029 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KZN84818.1 - 0.0092 15.2 0.0 0.02 14.1 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain Hydrolase_4 PF12146.8 KZN84818.1 - 0.01 15.1 0.0 0.028 13.7 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF2075 PF09848.9 KZN84818.1 - 0.017 14.4 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 KZN84818.1 - 0.02 14.8 0.0 0.056 13.4 0.0 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KZN84818.1 - 0.04 14.2 0.2 0.55 10.5 0.0 2.8 2 1 0 2 2 2 0 AAA domain LCAT PF02450.15 KZN84818.1 - 0.052 12.7 0.0 0.091 11.9 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase RNA_helicase PF00910.22 KZN84818.1 - 0.061 13.7 0.0 0.2 12.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 KZN84818.1 - 0.081 13.3 0.0 3.4 8.1 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UPF0565 PF10561.9 KZN84818.1 - 0.12 11.5 0.0 0.32 10.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 AAA_14 PF13173.6 KZN84818.1 - 0.17 11.9 0.0 1.8 8.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain AA_permease_2 PF13520.6 KZN84819.1 - 1.5e-47 162.5 39.3 1.7e-47 162.2 39.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN84819.1 - 1.3e-16 60.2 36.6 1.7e-16 59.9 36.6 1.1 1 0 0 1 1 1 1 Amino acid permease ketoacyl-synt PF00109.26 KZN84820.1 - 1.4e-75 254.2 0.0 3.8e-75 252.7 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KZN84820.1 - 5.5e-52 176.3 0.1 1e-51 175.4 0.1 1.5 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KZN84820.1 - 3.2e-44 151.7 0.0 5.7e-44 150.9 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KZN84820.1 - 9.8e-44 149.8 0.0 1.6e-43 149.1 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KZN84820.1 - 5.3e-30 103.8 0.0 1.6e-29 102.3 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KZN84820.1 - 5.3e-18 65.6 0.0 2.5e-17 63.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN84820.1 - 6.4e-15 55.4 0.0 1.8e-14 53.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KZN84820.1 - 1.4e-13 51.3 0.0 3.5e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KZN84820.1 - 5.7e-11 43.0 0.0 4.9e-10 40.0 0.0 2.7 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN84820.1 - 4.7e-10 40.0 0.0 1.3e-09 38.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN84820.1 - 5.6e-10 39.2 0.0 1.6e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KZN84820.1 - 2.3e-09 37.0 0.0 6.7e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Ubie_methyltran PF01209.18 KZN84820.1 - 5.3e-08 32.5 0.0 1.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 KZN84820.1 - 7.9e-07 28.9 0.1 2.1e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 KZN84820.1 - 4.2e-06 26.3 0.0 8.9e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 KZN84820.1 - 0.0016 18.8 0.2 0.0043 17.4 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site RrnaAD PF00398.20 KZN84820.1 - 0.0078 15.3 0.0 0.021 13.9 0.0 1.7 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase DUF5593 PF18007.1 KZN84820.1 - 0.09 13.5 0.1 8 7.2 0.0 3.0 3 0 0 3 3 2 0 Domain of unknown function (DUF5593) GKAP PF03359.13 KZN84820.1 - 0.1 12.2 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein DREV PF05219.12 KZN84820.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase 4_1_CTD PF05902.13 KZN84821.1 - 0.063 13.3 0.0 0.11 12.5 0.0 1.5 1 1 0 1 1 1 0 4.1 protein C-terminal domain (CTD) MFS_1 PF07690.16 KZN84822.1 - 1.6e-19 70.1 21.0 1.6e-19 70.1 21.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3267 PF11667.8 KZN84822.1 - 0.38 11.1 0.0 0.38 11.1 0.0 2.5 2 0 0 2 2 2 0 Putative zincin peptidase E1_dh PF00676.20 KZN84824.1 - 3.6e-109 364.3 0.6 4.3e-109 364.1 0.6 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KZN84824.1 - 0.066 12.4 0.1 0.12 11.5 0.1 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase HSP90 PF00183.18 KZN84826.1 - 1.9e-220 733.2 29.1 2.4e-220 732.8 29.1 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KZN84826.1 - 8.7e-15 55.2 0.1 1.7e-14 54.3 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KZN84826.1 - 5.5e-09 36.0 0.1 5.5e-09 36.0 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NTF2 PF02136.20 KZN84827.1 - 7.3e-27 94.3 0.2 1.2e-26 93.7 0.2 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KZN84827.1 - 8.7e-08 31.9 0.0 1.9e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_11 PF13414.6 KZN84829.1 - 0.009 15.7 4.2 0.33 10.7 0.0 4.1 5 0 0 5 5 5 2 TPR repeat TPR_17 PF13431.6 KZN84829.1 - 0.031 14.7 1.6 5.9 7.5 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Nnf1 PF03980.14 KZN84830.1 - 4.6e-33 113.9 6.5 7.3e-33 113.2 6.5 1.3 1 0 0 1 1 1 1 Nnf1 Dicty_CAR PF05462.11 KZN84830.1 - 3.8e-09 36.1 10.8 6.4e-09 35.4 10.8 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3 PF11710.8 KZN84830.1 - 3.9e-07 30.1 11.3 6e-07 29.4 11.3 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KZN84830.1 - 0.00018 20.9 0.0 0.00023 20.6 0.0 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) BAG6 PF12057.8 KZN84830.1 - 0.007 16.0 0.3 0.014 15.1 0.3 1.4 1 0 0 1 1 1 1 BCL2-associated athanogene 6 TMEMspv1-c74-12 PF11044.8 KZN84830.1 - 0.16 12.0 0.3 0.33 10.9 0.3 1.5 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein CAP_N PF01213.19 KZN84830.1 - 5.7 6.3 6.1 1.2 8.6 2.4 1.6 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Pkinase PF00069.25 KZN84831.1 - 1.8e-75 253.7 0.0 2.1e-75 253.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN84831.1 - 3.7e-36 124.7 0.0 4.9e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KZN84831.1 - 0.00012 21.2 0.0 0.0014 17.7 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KZN84831.1 - 0.0035 16.7 1.2 0.056 12.8 0.0 2.7 2 1 0 3 3 3 1 Kinase-like Kdo PF06293.14 KZN84831.1 - 0.0083 15.5 0.2 0.02 14.3 0.2 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KZN84831.1 - 0.038 13.1 0.0 0.15 11.1 0.0 1.8 2 0 0 2 2 2 0 Seadornavirus VP7 APH PF01636.23 KZN84831.1 - 0.04 13.8 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family SIR2 PF02146.17 KZN84832.1 - 1e-30 107.0 0.0 1.5e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Cation_efflux PF01545.21 KZN84833.1 - 1.2e-61 208.0 3.1 1.5e-61 207.6 3.1 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KZN84833.1 - 0.00017 21.6 0.6 0.00037 20.5 0.6 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter PAP2 PF01569.21 KZN84833.1 - 0.55 10.0 5.7 0.38 10.5 2.4 2.2 2 0 0 2 2 2 0 PAP2 superfamily SelP_N PF04592.14 KZN84833.1 - 0.78 9.1 7.2 1.7 8.0 7.2 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FGGY_C PF02782.16 KZN84834.1 - 2.4e-31 109.0 0.0 3.9e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KZN84834.1 - 6.6e-22 78.3 0.0 3.6e-13 49.7 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Xpo1 PF08389.12 KZN84835.1 - 2e-40 138.3 0.8 2.8e-39 134.6 0.0 3.4 4 0 0 4 4 4 1 Exportin 1-like protein HEAT PF02985.22 KZN84835.1 - 0.02 15.1 0.8 20 5.8 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat GFA PF04828.14 KZN84837.1 - 9.5e-25 86.8 0.3 1.4e-24 86.2 0.3 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Esterase PF00756.20 KZN84838.1 - 4.2e-55 187.1 0.0 5.3e-55 186.8 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 KZN84838.1 - 2.4e-06 27.2 0.0 0.00016 21.2 0.0 2.1 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KZN84838.1 - 4.7e-05 22.9 0.1 9.3e-05 22.0 0.1 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KZN84838.1 - 0.00035 19.9 0.0 0.00081 18.7 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 AXE1 PF05448.12 KZN84838.1 - 0.0038 16.0 0.0 0.0053 15.5 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.7 KZN84838.1 - 0.0091 14.9 0.0 0.026 13.4 0.0 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme Lipase_3 PF01764.25 KZN84838.1 - 0.021 14.7 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.7 KZN84838.1 - 0.07 13.7 0.3 0.11 13.1 0.3 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase PF07224.11 KZN84838.1 - 0.17 10.9 0.0 0.55 9.2 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase Abhydrolase_2 PF02230.16 KZN84838.1 - 0.18 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_C50 PF03568.17 KZN84839.1 - 1.3e-157 524.9 0.0 1.7e-156 521.3 0.0 2.6 2 0 0 2 2 2 1 Peptidase family C50 TPR_2 PF07719.17 KZN84839.1 - 7.1e-06 25.7 4.3 1.2 9.5 0.1 5.3 4 0 0 4 4 4 2 Tetratricopeptide repeat CHAT PF12770.7 KZN84839.1 - 3.4e-05 23.4 0.8 0.006 16.0 0.0 3.4 2 1 1 3 3 3 1 CHAT domain TPR_12 PF13424.6 KZN84839.1 - 0.0079 16.5 20.3 1.5 9.2 0.2 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KZN84839.1 - 0.045 13.6 1.4 38 4.3 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KZN84839.1 - 0.11 12.4 0.2 21 5.1 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KZN84839.1 - 0.28 11.5 1.9 16 6.0 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KZN84839.1 - 0.32 11.9 14.0 2.8 9.0 0.0 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat AAA_23 PF13476.6 KZN84839.1 - 1.7 9.1 5.3 4.9 7.6 1.2 2.8 2 0 0 2 2 2 0 AAA domain TPR_16 PF13432.6 KZN84839.1 - 2.4 8.9 10.6 48 4.7 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF5321 PF17254.2 KZN84840.1 - 3.4e-57 192.3 4.2 4.1e-57 192.1 4.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5321) Moulting_cycle PF04870.16 KZN84840.1 - 0.051 12.9 5.7 0.073 12.3 5.7 1.2 1 0 0 1 1 1 0 Moulting cycle Mito_carr PF00153.27 KZN84841.1 - 3.3e-73 241.7 0.0 1.4e-25 89.0 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KZN84841.1 - 7.1e-13 48.8 2.6 4.9e-07 30.1 0.7 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KZN84841.1 - 1.5e-12 46.4 4.7 1.9e-06 27.3 0.2 4.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 KZN84841.1 - 2.9e-11 42.1 3.0 5.9e-06 25.4 0.2 4.7 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 KZN84841.1 - 1.5e-07 31.2 0.1 1.5 8.7 0.0 4.7 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 KZN84841.1 - 1.2e-05 24.5 4.5 9.3e-05 21.8 0.3 3.2 3 0 0 3 3 3 1 EF hand GNAT_like PF18407.1 KZN84841.1 - 0.16 12.3 0.0 0.42 11.0 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyltransferase like domain Peptidase_M22 PF00814.25 KZN84843.1 - 6.5e-44 150.7 0.0 4.3e-43 148.0 0.0 2.1 1 1 0 1 1 1 1 Glycoprotease family FGGY_C PF02782.16 KZN84843.1 - 0.019 14.7 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain EPL1 PF10513.9 KZN84844.1 - 3.4e-31 108.7 0.0 1.3e-30 106.9 0.0 2.0 1 1 0 1 1 1 1 Enhancer of polycomb-like zf-HC5HC2H_2 PF13832.6 KZN84844.1 - 1.3e-30 105.8 5.0 1.3e-30 105.8 5.0 2.2 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KZN84844.1 - 4.2e-26 91.0 1.7 4.2e-26 91.0 1.7 2.9 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KZN84844.1 - 3.4e-15 55.3 7.9 5.6e-14 51.4 1.9 2.6 2 0 0 2 2 2 2 PHD-finger PHD PF00628.29 KZN84844.1 - 4.1e-10 39.4 19.8 9e-09 35.1 9.3 2.6 2 0 0 2 2 2 2 PHD-finger Bromodomain PF00439.25 KZN84844.1 - 0.093 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Bromodomain zf-RING-like PF08746.11 KZN84844.1 - 3.5 8.0 19.8 0.032 14.6 4.6 2.5 2 0 0 2 2 2 0 RING-like domain zf-PHD-like PF15446.6 KZN84844.1 - 4.3 6.9 11.8 0.032 13.8 2.4 2.1 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.6 KZN84844.1 - 8.9 6.3 15.9 0.76 9.8 7.3 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 RRM_1 PF00076.22 KZN84845.1 - 1.8e-20 72.5 0.0 2.6e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KZN84845.1 - 0.00038 20.0 0.0 0.00056 19.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dpy-30 PF05186.13 KZN84846.1 - 3.6e-15 55.4 0.0 4.8e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif VRR_NUC PF08774.11 KZN84847.1 - 2.4e-24 85.5 0.0 7.6e-24 83.9 0.0 1.9 1 0 0 1 1 1 1 VRR-NUC domain FANC_SAP PF18081.1 KZN84847.1 - 1.2 9.4 5.6 1.1 9.4 3.3 2.2 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain Ribosomal_S13_N PF08069.12 KZN84848.1 - 3.8e-28 97.3 0.1 6.1e-28 96.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KZN84848.1 - 6e-15 55.2 0.1 8.1e-15 54.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 KZN84848.1 - 0.02 14.8 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain OGG_N PF07934.12 KZN84849.1 - 1.5e-36 125.1 0.3 3e-36 124.2 0.3 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KZN84849.1 - 3.4e-15 56.4 0.0 3.3e-14 53.2 0.0 2.2 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein RRM_1 PF00076.22 KZN84850.1 - 1.2e-28 98.8 0.2 1.9e-12 46.8 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KZN84850.1 - 3.4e-05 23.6 0.0 0.08 12.8 0.0 3.0 3 0 0 3 3 3 2 Occluded RNA-recognition motif BRAP2 PF07576.12 KZN84850.1 - 0.013 15.7 0.0 10 6.4 0.0 3.2 3 0 0 3 3 3 0 BRCA1-associated protein 2 CARD PF00619.21 KZN84850.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Caspase recruitment domain Septin PF00735.18 KZN84851.1 - 1.8e-120 401.5 0.1 3e-120 400.7 0.1 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KZN84851.1 - 1.4e-07 31.6 0.6 2.6e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KZN84851.1 - 8.7e-07 28.7 0.7 0.0002 20.9 0.0 2.7 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KZN84851.1 - 7.7e-06 25.9 1.3 0.00036 20.5 0.3 2.8 2 1 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 KZN84851.1 - 0.00018 20.9 0.8 0.00047 19.5 0.0 2.0 2 0 0 2 2 2 1 AIG1 family ABC_tran PF00005.27 KZN84851.1 - 0.00028 21.4 2.0 0.027 15.0 0.0 2.8 2 1 0 3 3 3 1 ABC transporter Roc PF08477.13 KZN84851.1 - 0.00074 19.7 0.0 0.0016 18.6 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KZN84851.1 - 0.0018 17.9 0.1 0.019 14.5 0.0 2.5 2 0 0 2 2 2 1 Ras family AAA_16 PF13191.6 KZN84851.1 - 0.0019 18.6 0.1 0.0057 17.1 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KZN84851.1 - 0.0033 17.7 0.7 0.013 15.8 0.1 2.3 2 2 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 KZN84851.1 - 0.0058 16.4 0.6 1.4 8.6 0.1 3.2 1 1 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 KZN84851.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KZN84851.1 - 0.032 13.9 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KZN84851.1 - 0.058 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_7 PF12775.7 KZN84851.1 - 0.089 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 KZN84851.1 - 0.091 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KZN84851.1 - 0.17 12.3 0.2 0.67 10.4 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Exonuc_VII_L PF02601.15 KZN84851.1 - 0.52 9.8 4.2 0.95 9.0 4.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit IIGP PF05049.13 KZN84851.1 - 0.57 9.2 4.1 0.28 10.2 0.2 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.23 KZN84851.1 - 0.69 10.0 7.5 0.76 9.8 0.1 3.3 3 2 0 4 4 4 0 Dynamin family TSNAXIP1_N PF15739.5 KZN84851.1 - 1.1 9.7 11.2 5.8 7.3 0.0 2.9 2 1 1 3 3 3 0 Translin-associated factor X-interacting N-terminus DUF3987 PF13148.6 KZN84851.1 - 6.9 5.6 8.5 1.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) POB3_N PF17292.2 KZN84852.1 - 1.5e-30 105.4 0.2 4.5e-29 100.7 0.0 2.8 3 0 0 3 3 3 1 POB3-like N-terminal PH domain SSrecog PF03531.14 KZN84852.1 - 4.2e-29 100.3 1.9 2e-28 98.1 0.0 3.1 5 0 0 5 5 5 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 KZN84852.1 - 4e-27 94.5 0.1 6.4e-26 90.6 0.0 2.7 3 0 0 3 3 3 1 Histone chaperone Rttp106-like PH_TFIIH PF08567.11 KZN84852.1 - 0.026 14.8 0.0 0.85 10.0 0.0 3.1 4 0 0 4 4 4 0 TFIIH p62 subunit, N-terminal domain Putative_PNPOx PF01243.20 KZN84853.1 - 0.00039 20.6 0.0 0.00075 19.6 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Rax2 PF12768.7 KZN84854.1 - 1.9e-68 230.1 6.2 2.5e-67 226.5 0.0 3.9 4 1 1 5 5 5 2 Cortical protein marker for cell polarity NolX PF05819.11 KZN84854.1 - 0.069 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 NolX protein Zn_clus PF00172.18 KZN84855.1 - 1.7e-07 31.2 12.4 3.2e-07 30.4 12.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KZN84855.1 - 5.7e-06 25.4 0.8 8.7e-05 21.5 0.8 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain SH3_3 PF08239.11 KZN84857.1 - 0.00027 21.1 0.1 0.00048 20.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_4 PF06347.13 KZN84857.1 - 0.098 12.5 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain UPF0121 PF03661.13 KZN84858.1 - 1.4e-31 109.8 9.5 1.8e-31 109.4 9.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Mito_carr PF00153.27 KZN84859.1 - 8.1e-62 205.2 1.1 1.3e-19 69.9 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Rho_N PF07498.12 KZN84860.1 - 0.024 14.6 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain SWIRM-assoc_2 PF16496.5 KZN84860.1 - 0.093 11.6 2.7 0.13 11.1 2.7 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal TPK_catalytic PF04263.16 KZN84861.1 - 3.9e-32 110.8 0.0 9.8e-32 109.5 0.0 1.7 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KZN84861.1 - 6.5e-20 70.6 0.0 1.1e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain CHCH PF06747.13 KZN84862.1 - 1.1e-07 31.7 4.4 2e-07 31.0 4.4 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 KZN84862.1 - 0.054 13.9 1.4 0.1 13.0 1.4 1.5 1 0 0 1 1 1 0 GCK domain Death PF00531.22 KZN84862.1 - 0.093 12.9 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Death domain PfkB PF00294.24 KZN84863.1 - 2.4e-15 56.7 0.0 3.1e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Methyltransf_2 PF00891.18 KZN84864.1 - 6.4e-21 74.6 0.0 9.5e-21 74.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 KZN84864.1 - 0.019 14.9 0.0 0.049 13.7 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain Dimerisation2 PF16864.5 KZN84864.1 - 0.022 14.7 0.0 0.064 13.2 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain Rrf2 PF02082.20 KZN84864.1 - 0.13 12.6 0.0 0.62 10.4 0.0 2.0 3 0 0 3 3 3 0 Transcriptional regulator ADH_N PF08240.12 KZN84866.1 - 4e-10 39.5 0.2 1.3e-09 37.9 0.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN84866.1 - 1.1e-08 35.1 0.2 2.3e-08 34.1 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ribosomal_L1 PF00687.21 KZN84867.1 - 8.7e-61 205.2 4.9 1.4e-60 204.5 4.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Cas6_N PF17952.1 KZN84867.1 - 0.059 13.6 0.1 0.17 12.2 0.1 1.8 1 0 0 1 1 1 0 Cas6 N-terminal domain ETF PF01012.21 KZN84868.1 - 2.7e-44 151.2 2.9 3.1e-44 151.0 1.9 1.6 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KZN84868.1 - 1.5e-32 111.4 0.1 3.2e-32 110.4 0.1 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain AAA PF00004.29 KZN84869.1 - 1.8e-11 44.6 0.0 5.2e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KZN84869.1 - 2e-06 28.1 0.0 4.5e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KZN84869.1 - 4.6e-05 23.4 0.0 0.00011 22.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KZN84869.1 - 9.2e-05 22.2 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KZN84869.1 - 0.00045 20.2 0.1 0.0018 18.2 0.0 2.1 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_33 PF13671.6 KZN84869.1 - 0.0011 19.1 0.0 0.0028 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KZN84869.1 - 0.0012 19.2 0.1 0.0095 16.3 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 KZN84869.1 - 0.022 14.8 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KZN84869.1 - 0.047 13.6 0.0 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 KZN84869.1 - 0.09 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SASRP1 PF15160.6 KZN84870.1 - 1.5 8.4 6.9 1.5 8.5 6.9 1.0 1 0 0 1 1 1 0 Spermatogenesis-associated serine-rich protein 1 Dysbindin PF04440.16 KZN84870.1 - 2 8.6 6.6 2.3 8.4 6.6 1.1 1 0 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) GST_C PF00043.25 KZN84871.1 - 1e-15 57.7 0.0 1.8e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KZN84871.1 - 4.8e-14 52.5 0.0 7.7e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KZN84871.1 - 6.2e-13 48.9 0.0 2.8e-12 46.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KZN84871.1 - 5.5e-11 42.6 0.0 1e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KZN84871.1 - 1e-09 38.5 0.0 1.7e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KZN84871.1 - 4.9e-06 26.5 0.0 2.9e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KZN84871.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SUN PF03856.13 KZN84872.1 - 3e-91 305.2 4.7 4.4e-91 304.7 4.7 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) SOG2 PF10428.9 KZN84872.1 - 0.0047 16.2 2.4 0.0053 16.0 2.4 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein MIF4G PF02854.19 KZN84875.1 - 4.2e-60 203.0 0.0 1.8e-34 119.3 0.0 3.4 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 KZN84875.1 - 5.5e-41 140.5 10.5 5.5e-41 140.5 10.5 2.9 4 0 0 4 4 4 1 Up-frameshift suppressor 2 TRI12 PF06609.13 KZN84876.1 - 1.4e-38 132.7 26.3 1.8e-38 132.3 26.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KZN84876.1 - 3.6e-07 29.4 48.1 3.6e-07 29.4 48.1 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3087 PF11286.8 KZN84876.1 - 0.15 11.6 4.1 5.7 6.4 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) adh_short PF00106.25 KZN84877.1 - 1.4e-41 142.1 0.0 1.8e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN84877.1 - 7.9e-31 107.4 0.0 1.1e-30 107.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN84877.1 - 3.2e-05 23.9 0.0 7.6e-05 22.7 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KZN84877.1 - 0.039 13.4 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KZN84878.1 - 9e-33 113.4 0.0 1.3e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN84878.1 - 1.4e-27 96.8 0.0 5.1e-27 94.9 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN84880.1 - 6.5e-26 91.0 0.0 4.3e-25 88.3 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN84880.1 - 2.1e-19 70.0 0.0 6.2e-19 68.5 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN84880.1 - 6.1e-06 26.3 0.1 1.4e-05 25.0 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KZN84880.1 - 0.0045 16.5 0.0 0.0089 15.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KZN84880.1 - 0.019 14.9 0.1 0.034 14.0 0.1 1.4 2 0 0 2 2 2 0 NAD(P)H-binding FAD_binding_4 PF01565.23 KZN84882.1 - 1.3e-19 70.3 2.1 2.1e-19 69.7 2.1 1.3 1 0 0 1 1 1 1 FAD binding domain adh_short PF00106.25 KZN84883.1 - 5.8e-35 120.5 0.1 8.6e-35 120.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN84883.1 - 2.2e-26 92.9 0.1 3.1e-26 92.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KZN84883.1 - 0.0025 17.7 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KZN84883.1 - 0.004 16.6 0.0 0.0076 15.7 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family AlaDh_PNT_C PF01262.21 KZN84883.1 - 0.0057 16.0 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KZN84883.1 - 0.028 13.8 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain KR PF08659.10 KZN84883.1 - 0.036 14.0 0.0 0.097 12.6 0.0 1.7 1 1 0 1 1 1 0 KR domain p450 PF00067.22 KZN84884.1 - 8.5e-38 130.3 0.1 1.1e-37 129.8 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KZN84885.1 - 5e-48 164.0 0.0 6.7e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3237 PF11578.8 KZN84886.1 - 6.8e-30 103.9 0.0 8.1e-30 103.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Transferase PF02458.15 KZN84887.1 - 1.9e-18 66.4 0.0 5.5e-12 45.1 0.0 2.9 3 0 0 3 3 3 3 Transferase family p450 PF00067.22 KZN84888.1 - 9.4e-70 235.6 0.0 1.1e-69 235.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF5446 PF17522.2 KZN84889.1 - 0.059 13.5 0.1 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5446) p450 PF00067.22 KZN84890.1 - 3.2e-69 233.9 0.0 3.7e-69 233.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NACHT_N PF17100.5 KZN84891.1 - 4.5e-54 183.6 0.1 7.7e-54 182.9 0.1 1.3 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase WD40 PF00400.32 KZN84891.1 - 1.3e-50 168.3 42.7 8e-11 42.3 1.1 12.0 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN84891.1 - 1.4e-24 86.2 1.3 0.00056 20.1 0.0 8.1 2 2 7 9 9 9 6 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KZN84891.1 - 3.3e-14 53.1 0.0 1e-13 51.5 0.0 1.8 2 0 0 2 2 2 1 NACHT domain Ge1_WD40 PF16529.5 KZN84891.1 - 1e-08 34.5 1.9 0.016 14.2 0.0 5.4 3 2 3 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KZN84891.1 - 2.2e-06 27.2 0.0 0.073 12.4 0.0 2.9 3 0 0 3 3 3 2 WD40-like domain Cytochrom_D1 PF02239.16 KZN84891.1 - 5e-05 22.0 0.0 0.00028 19.5 0.0 2.1 3 0 0 3 3 3 1 Cytochrome D1 heme domain Nup160 PF11715.8 KZN84891.1 - 0.00018 20.3 0.1 0.079 11.6 0.0 3.8 2 1 1 3 3 3 1 Nucleoporin Nup120/160 CDtoxinA PF03498.14 KZN84891.1 - 0.0002 21.0 0.0 4.3 6.9 0.0 4.3 2 2 2 4 4 4 1 Cytolethal distending toxin A/C domain AAA_16 PF13191.6 KZN84891.1 - 0.004 17.6 0.0 0.017 15.5 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain PD40 PF07676.12 KZN84891.1 - 0.037 14.0 0.4 7.5 6.6 0.1 3.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat KAP_NTPase PF07693.14 KZN84891.1 - 0.058 12.6 0.0 0.44 9.7 0.1 2.0 1 1 0 2 2 2 0 KAP family P-loop domain ATPase_2 PF01637.18 KZN84891.1 - 0.23 11.3 1.0 2.4 8.0 0.0 2.5 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea Alpha-amylase PF00128.24 KZN84892.1 - 1.1e-28 100.8 0.0 2.4e-28 99.7 0.0 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KZN84892.1 - 0.0024 18.1 0.0 0.0066 16.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Alpha-amylase PF00128.24 KZN84893.1 - 4e-23 82.5 0.0 5.1e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Tad PF13400.6 KZN84894.1 - 0.31 11.4 7.4 1.4 9.3 2.3 3.1 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like MFS_1 PF07690.16 KZN84894.1 - 0.55 9.1 17.7 2.3 7.1 11.9 2.6 1 1 1 2 2 2 0 Major Facilitator Superfamily Wzy_C_2 PF11846.8 KZN84894.1 - 3.2 7.6 7.3 1.1 9.1 0.4 2.4 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal DUF3176 PF11374.8 KZN84895.1 - 4.6e-35 120.1 2.4 9.3e-35 119.1 2.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) HlyIII PF03006.20 KZN84897.1 - 8.3e-48 163.0 14.4 1e-47 162.7 14.4 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF4231 PF14015.6 KZN84897.1 - 0.46 11.0 4.3 4.9 7.7 0.7 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) S1-P1_nuclease PF02265.16 KZN84898.1 - 8e-68 229.0 0.1 9.4e-68 228.8 0.1 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease AA_permease_2 PF13520.6 KZN84899.1 - 1.6e-64 218.3 45.4 1.9e-64 218.1 45.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN84899.1 - 3.6e-15 55.5 34.1 4.8e-15 55.1 34.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3632 PF12311.8 KZN84901.1 - 2.9e-36 125.5 2.8 3.9e-36 125.1 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Uso1_p115_head PF04869.14 KZN84901.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, head region F-box-like PF12937.7 KZN84903.1 - 0.00031 20.6 0.1 0.0006 19.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KZN84903.1 - 0.061 13.2 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 F-box Ank_4 PF13637.6 KZN84904.1 - 9.7e-38 128.1 6.7 1.1e-08 35.4 0.0 6.4 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 KZN84904.1 - 2.1e-37 127.5 0.4 1.1e-13 51.5 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KZN84904.1 - 1.5e-35 120.7 1.0 3.6e-11 43.1 0.1 7.9 4 3 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN84904.1 - 9.4e-28 93.2 3.4 0.00042 20.5 0.0 8.5 8 1 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 KZN84904.1 - 9.1e-26 89.1 3.8 0.00029 21.1 0.1 8.2 8 0 0 8 8 8 6 Ankyrin repeat DUF2183 PF09949.9 KZN84905.1 - 5.5e-18 65.1 0.0 1.1e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Gly_transf_sug PF04488.15 KZN84906.1 - 8.3e-11 42.4 0.1 1.6e-10 41.5 0.1 1.5 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KZN84906.1 - 0.035 13.4 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Rotavirus_VP1 PF12289.8 KZN84906.1 - 0.15 11.0 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 Rotavirus VP1 C-terminal domain 5-FTHF_cyc-lig PF01812.20 KZN84907.1 - 0.18 11.6 0.0 0.38 10.6 0.0 1.6 2 0 0 2 2 2 0 5-formyltetrahydrofolate cyclo-ligase family DUF5463 PF17551.2 KZN84907.1 - 0.3 11.0 1.5 0.54 10.2 1.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5463) SWIRM PF04433.17 KZN84909.1 - 7.6e-32 109.5 0.1 2e-31 108.2 0.1 1.8 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KZN84909.1 - 4.5e-31 106.6 12.5 9.3e-31 105.6 12.5 1.6 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KZN84909.1 - 1.4e-08 34.8 0.1 3e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KZN84909.1 - 4.5e-06 26.8 0.1 9.9e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Mei5 PF10376.9 KZN84909.1 - 0.053 13.4 3.4 0.095 12.5 3.4 1.3 1 0 0 1 1 1 0 Double-strand recombination repair protein AAA_9 PF12781.7 KZN84909.1 - 0.26 10.4 2.4 0.47 9.5 2.4 1.3 1 0 0 1 1 1 0 ATP-binding dynein motor region DUF883 PF05957.13 KZN84909.1 - 1.1 9.9 9.8 0.85 10.3 3.9 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) ZZ PF00569.17 KZN84909.1 - 1.4 8.7 5.8 13 5.7 5.8 2.1 1 1 0 1 1 1 0 Zinc finger, ZZ type SPESP1 PF15754.5 KZN84910.1 - 6.2 5.9 12.8 10 5.2 12.8 1.3 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 ResIII PF04851.15 KZN84911.1 - 9.7e-24 84.3 0.0 5.2e-23 81.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KZN84911.1 - 3.8e-13 49.8 0.0 5.1e-12 46.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KZN84911.1 - 1.7e-09 37.7 0.0 3.7e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KZN84911.1 - 2.3e-06 27.4 0.0 4.2e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 KZN84911.1 - 0.00043 19.6 0.0 0.00069 19.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 KZN84912.1 - 5.9e-46 156.4 0.1 2.1e-23 83.4 0.1 3.7 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 KZN84912.1 - 2.6e-30 104.3 3.2 7.4e-30 102.8 3.2 1.9 1 0 0 1 1 1 1 Four helical bundle domain AAA_21 PF13304.6 KZN84912.1 - 6.2e-15 55.8 0.1 0.0023 17.8 0.0 4.4 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KZN84912.1 - 4.7e-13 49.1 0.1 0.00011 21.7 0.0 4.0 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KZN84912.1 - 1.3e-09 38.9 0.0 0.0016 19.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KZN84912.1 - 5.1e-08 32.5 0.2 0.0095 15.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 KZN84912.1 - 7.6e-08 32.8 0.0 0.012 15.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KZN84912.1 - 4.1e-06 26.9 0.1 0.0045 17.1 0.0 3.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KZN84912.1 - 7.5e-06 25.8 0.0 0.16 11.7 0.0 2.8 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KZN84912.1 - 1.2e-05 25.6 0.0 0.025 14.8 0.0 3.2 3 0 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 KZN84912.1 - 1.2e-05 25.2 0.0 0.012 15.6 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KZN84912.1 - 1.2e-05 25.8 0.0 0.13 12.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KZN84912.1 - 1.7e-05 25.2 1.0 0.32 11.4 0.0 3.8 4 1 0 4 4 4 2 AAA ATPase domain RNA_helicase PF00910.22 KZN84912.1 - 9.4e-05 22.8 0.0 0.47 10.9 0.0 2.8 2 0 0 2 2 2 2 RNA helicase DUF87 PF01935.17 KZN84912.1 - 0.00012 22.3 0.4 0.064 13.3 0.2 3.0 3 0 0 3 3 2 1 Helicase HerA, central domain NACHT PF05729.12 KZN84912.1 - 0.00017 21.5 0.0 0.12 12.3 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.6 KZN84912.1 - 0.00022 21.2 0.0 0.35 10.9 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 KZN84912.1 - 0.00029 21.3 0.0 0.21 12.0 0.0 4.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KZN84912.1 - 0.00032 20.5 0.0 1.1 8.8 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 KZN84912.1 - 0.00044 20.3 0.0 0.0018 18.3 0.0 2.1 2 0 0 2 2 2 1 Dynamin family G-alpha PF00503.20 KZN84912.1 - 0.00055 19.2 0.0 0.83 8.7 0.0 2.6 2 0 0 2 2 2 2 G-protein alpha subunit NB-ARC PF00931.22 KZN84912.1 - 0.0012 18.1 0.1 0.026 13.7 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.6 KZN84912.1 - 0.0015 18.7 0.0 3.1 8.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_13 PF13166.6 KZN84912.1 - 0.0015 17.2 0.0 0.37 9.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain cobW PF02492.19 KZN84912.1 - 0.0018 17.9 0.5 0.71 9.4 0.0 3.5 4 0 0 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 KZN84912.1 - 0.0019 18.0 0.0 1.5 8.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 KZN84912.1 - 0.0019 17.8 0.1 0.44 10.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 KZN84912.1 - 0.002 17.2 0.2 0.91 8.4 0.1 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KZN84912.1 - 0.002 17.9 0.0 1.1 8.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.6 KZN84912.1 - 0.0068 16.6 0.0 2.1 8.6 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 KZN84912.1 - 0.0071 15.9 0.0 4.4 6.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KZN84912.1 - 0.0099 16.1 0.0 5.5 7.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KZN84912.1 - 0.02 14.7 0.0 6.5 6.5 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MukB PF04310.12 KZN84912.1 - 0.027 14.3 0.0 6.1 6.6 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal ATP-synt_ab PF00006.25 KZN84912.1 - 0.031 13.9 0.0 3 7.4 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Septin PF00735.18 KZN84912.1 - 0.034 13.4 0.2 3.2 7.0 0.0 2.8 3 0 0 3 3 3 0 Septin AAA_7 PF12775.7 KZN84912.1 - 0.044 13.3 0.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KZN84912.1 - 0.05 13.5 0.2 0.73 9.7 0.0 2.7 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea TsaE PF02367.17 KZN84912.1 - 0.05 13.6 0.1 8.1 6.5 0.0 2.8 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Arf PF00025.21 KZN84912.1 - 0.074 12.5 0.1 7 6.1 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family PRK PF00485.18 KZN84912.1 - 0.11 12.3 0.0 4.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family FtsK_SpoIIIE PF01580.18 KZN84912.1 - 0.11 11.8 1.1 0.52 9.6 0.1 2.5 3 0 0 3 3 3 0 FtsK/SpoIIIE family CLP1_P PF16575.5 KZN84912.1 - 0.15 11.9 0.9 3.8 7.3 0.0 3.0 3 0 0 3 3 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Tmemb_14 PF03647.13 KZN84913.1 - 2.4e-23 82.7 4.1 2.7e-23 82.5 4.1 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C PGAP1 PF07819.13 KZN84914.1 - 8.9e-90 300.4 0.0 1.6e-89 299.6 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KZN84914.1 - 1.7e-07 32.1 0.4 4e-07 30.9 0.4 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KZN84914.1 - 5.4e-05 23.0 0.5 0.00019 21.2 0.5 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 KZN84914.1 - 0.00083 19.3 0.0 0.0018 18.1 0.0 1.6 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Esterase PF00756.20 KZN84914.1 - 0.0014 18.3 0.0 0.016 14.9 0.0 2.1 2 0 0 2 2 2 1 Putative esterase DUF676 PF05057.14 KZN84914.1 - 0.0041 16.7 0.0 0.0077 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KZN84914.1 - 0.0041 16.4 0.0 0.0096 15.2 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 LCAT PF02450.15 KZN84914.1 - 0.012 14.9 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_3 PF07859.13 KZN84914.1 - 0.069 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.8 KZN84914.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Sugar_tr PF00083.24 KZN84915.1 - 4.6e-38 131.2 14.6 5.5e-37 127.7 14.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN84915.1 - 3.9e-34 118.1 31.6 9.2e-32 110.3 19.8 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_9_N PF15420.6 KZN84915.1 - 0.17 11.8 5.2 0.082 12.9 0.7 2.4 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus OATP PF03137.20 KZN84915.1 - 1.2 7.4 4.4 30 2.7 4.4 2.2 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Rick_17kDa_Anti PF05433.15 KZN84916.1 - 4.3e-05 23.3 15.5 7.6e-05 22.5 15.5 1.4 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 KZN84916.1 - 0.014 15.4 10.3 0.028 14.4 10.3 1.5 1 0 0 1 1 1 0 Glycine zipper Dehydrin PF00257.19 KZN84916.1 - 0.015 15.9 10.2 0.016 15.8 10.2 1.4 1 1 0 1 1 1 0 Dehydrin SNARE_assoc PF09335.11 KZN84916.1 - 0.099 13.1 0.0 0.14 12.7 0.0 1.1 1 0 0 1 1 1 0 SNARE associated Golgi protein DUF3824 PF12868.7 KZN84916.1 - 0.1 13.2 0.7 0.1 13.2 0.7 3.1 2 1 0 2 2 2 0 Domain of unknwon function (DUF3824) Gly-zipper_YMGG PF13441.6 KZN84916.1 - 0.16 11.8 11.2 0.29 10.9 11.2 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper DUF533 PF04391.12 KZN84916.1 - 0.19 11.3 1.8 0.36 10.4 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Bacteriocin_IIc PF10439.9 KZN84916.1 - 0.8 9.9 10.0 1.6 8.9 10.0 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF755 PF05501.11 KZN84916.1 - 2.3 8.5 18.9 3.2 8.1 18.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) AP3D1 PF06375.11 KZN84916.1 - 7 6.9 12.6 9.3 6.5 12.6 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Complex1_LYR PF05347.15 KZN84917.1 - 0.0014 18.6 0.1 0.0041 17.1 0.1 1.9 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Ank_4 PF13637.6 KZN84918.1 - 1.1e-10 41.8 0.2 1.5e-07 31.8 0.0 3.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KZN84918.1 - 8.5e-05 23.1 0.0 0.064 13.8 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KZN84918.1 - 0.0018 18.6 2.0 0.96 10.2 0.1 3.9 3 1 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KZN84918.1 - 0.0022 18.2 0.4 0.13 12.6 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) KilA-N PF04383.13 KZN84918.1 - 0.0036 17.1 0.4 0.025 14.4 0.4 2.2 1 1 0 1 1 1 1 KilA-N domain Cellulase PF00150.18 KZN84919.1 - 1.1e-30 107.1 2.2 2.6e-30 105.8 0.8 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) TPR_2 PF07719.17 KZN84920.1 - 0.00017 21.4 9.1 0.02 15.0 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KZN84920.1 - 0.029 14.2 5.4 0.29 11.0 0.0 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Pro_dh-DNA_bdg PF14850.6 KZN84920.1 - 0.052 14.1 0.0 0.18 12.4 0.0 2.0 1 0 0 1 1 1 0 DNA-binding domain of Proline dehydrogenase TPR_7 PF13176.6 KZN84920.1 - 0.063 13.3 0.5 2.6 8.3 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KZN84920.1 - 0.077 13.4 0.0 7.6 7.2 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Methyltransf_10 PF05971.12 KZN84921.1 - 2.2e-59 201.3 0.0 2.8e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 KZN84921.1 - 3.4e-06 26.7 0.0 8e-06 25.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 KZN84921.1 - 0.0028 17.1 0.0 0.0043 16.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 KZN84921.1 - 0.033 13.7 0.0 0.058 13.0 0.0 1.5 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_16 PF10294.9 KZN84921.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase DUF2357 PF09823.9 KZN84921.1 - 0.088 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) MFS_1 PF07690.16 KZN84922.1 - 1.1e-43 149.5 36.3 1.4e-39 136.0 21.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN84922.1 - 1.6e-07 30.6 16.4 1.6e-07 30.6 16.4 3.2 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 KZN84922.1 - 4.9e-06 25.6 2.2 4.9e-06 25.6 2.2 2.4 2 0 0 2 2 2 1 MFS_1 like family OATP PF03137.20 KZN84922.1 - 0.15 10.3 14.7 0.22 9.8 1.2 2.7 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Dabb PF07876.12 KZN84922.1 - 0.17 12.5 0.0 0.33 11.6 0.0 1.4 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain DUF4362 PF14275.6 KZN84923.1 - 0.22 11.8 0.0 0.36 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4362) Ribonuc_L-PSP PF01042.21 KZN84925.1 - 4.2e-20 71.9 0.0 5.1e-20 71.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF4602 PF15375.6 KZN84926.1 - 2e-12 47.6 18.5 6.3e-12 46.0 18.5 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) DUF4055 PF13264.6 KZN84926.1 - 0.16 12.1 1.7 2.7 8.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) His_biosynth PF00977.21 KZN84927.1 - 3.4e-32 111.8 0.0 4.5e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein MARVEL PF01284.23 KZN84928.1 - 0.0066 16.5 0.6 0.0081 16.2 0.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain Yip1 PF04893.17 KZN84928.1 - 0.012 15.3 1.0 0.012 15.3 0.5 1.3 1 1 0 1 1 1 0 Yip1 domain DUF4064 PF13273.6 KZN84928.1 - 0.031 14.6 0.7 0.039 14.2 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) TMEMspv1-c74-12 PF11044.8 KZN84928.1 - 0.28 11.2 1.1 13 5.9 0.0 2.2 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein CoA_binding PF02629.19 KZN84929.1 - 1.4e-26 93.0 2.2 5.6e-26 91.1 0.6 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KZN84929.1 - 8.5e-22 77.6 0.1 1.4e-21 77.0 0.1 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KZN84929.1 - 1.4e-07 31.4 0.0 2.9e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KZN84929.1 - 0.0027 18.2 0.0 0.0062 17.0 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain Isochorismatase PF00857.20 KZN84931.1 - 3.9e-18 66.2 0.0 7.5e-18 65.3 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family MC1 PF05854.11 KZN84932.1 - 0.13 12.6 0.6 0.34 11.2 0.6 1.7 1 0 0 1 1 1 0 Non-histone chromosomal protein MC1 SDA1 PF05285.12 KZN84932.1 - 0.21 11.0 17.8 0.29 10.5 17.8 1.1 1 0 0 1 1 1 0 SDA1 ADH_zinc_N PF00107.26 KZN84934.1 - 7.8e-29 100.3 0.4 1.6e-28 99.3 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KZN84934.1 - 1.6e-21 77.7 0.1 3.1e-21 76.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KZN84934.1 - 7.5e-10 38.7 0.0 3.5e-09 36.5 0.0 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KZN84934.1 - 0.00072 19.1 0.1 0.001 18.6 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KZN84934.1 - 0.0013 18.1 0.4 0.0019 17.5 0.4 1.4 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.21 KZN84934.1 - 0.022 14.5 0.1 0.035 13.8 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 KZN84934.1 - 0.075 12.4 0.0 0.31 10.4 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KZN84934.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain FA_desaturase PF00487.24 KZN84935.1 - 1.2e-12 48.2 23.7 1.2e-12 48.2 23.7 1.7 1 1 1 2 2 2 1 Fatty acid desaturase RseC_MucC PF04246.12 KZN84935.1 - 0.17 11.8 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Arylsulfotran_2 PF14269.6 KZN84936.1 - 5.1e-47 160.7 0.0 8.4e-47 160.0 0.0 1.4 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KZN84936.1 - 5.6e-20 71.6 0.0 1.6e-19 70.1 0.0 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PepSY PF03413.19 KZN84936.1 - 0.083 13.5 0.7 43 4.8 0.0 3.7 3 1 1 4 4 4 0 Peptidase propeptide and YPEB domain PQQ_2 PF13360.6 KZN84936.1 - 0.11 12.1 0.0 3.7 7.1 0.0 2.7 3 0 0 3 3 3 0 PQQ-like domain DUF1513 PF07433.11 KZN84936.1 - 0.12 11.4 0.0 1.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) DUF455 PF04305.14 KZN84938.1 - 1.2e-99 332.9 0.0 1.4e-99 332.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.26 KZN84938.1 - 5.1e-06 26.4 0.0 9.4e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KZN84938.1 - 8.5e-05 22.4 0.0 0.00024 21.0 0.0 1.8 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Amidohydro_3 PF07969.11 KZN84942.1 - 4.4e-67 227.6 1.1 5e-67 227.4 1.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KZN84942.1 - 1.4e-12 47.6 0.2 4.2e-07 29.6 0.0 3.0 2 1 0 2 2 2 2 Amidohydrolase family Phage_sheath_1 PF04984.14 KZN84942.1 - 0.05 13.5 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 Phage tail sheath protein subtilisin-like domain APC1_C PF18122.1 KZN84942.1 - 0.18 11.8 0.0 0.44 10.5 0.0 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain MFS_1 PF07690.16 KZN84944.1 - 1.8e-31 109.4 30.4 1.8e-31 109.4 30.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3007 PF11460.8 KZN84944.1 - 2.8 8.2 6.3 0.42 10.9 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) STE PF02200.16 KZN84945.1 - 5.2e-55 184.6 0.0 8e-55 184.0 0.0 1.3 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 KZN84945.1 - 2.6e-12 46.5 10.4 1.9e-06 28.0 0.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KZN84945.1 - 9.5e-09 35.3 4.0 9.5e-09 35.3 4.0 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KZN84945.1 - 1.4e-08 34.8 8.4 0.00093 19.8 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KZN84945.1 - 0.00033 20.6 4.3 0.0015 18.5 0.1 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KZN84945.1 - 0.0041 17.4 0.1 0.93 9.9 0.0 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding mit_SMPDase PF14724.6 KZN84945.1 - 0.037 12.0 1.3 0.056 11.4 1.3 1.1 1 0 0 1 1 1 0 Mitochondrial-associated sphingomyelin phosphodiesterase zf-TRAF PF02176.18 KZN84945.1 - 0.04 14.6 2.4 0.093 13.4 2.4 1.6 1 0 0 1 1 1 0 TRAF-type zinc finger NOA36 PF06524.12 KZN84945.1 - 0.088 12.1 0.3 0.14 11.5 0.3 1.2 1 0 0 1 1 1 0 NOA36 protein zf-Di19 PF05605.12 KZN84945.1 - 0.11 12.8 2.7 0.28 11.5 2.7 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 KZN84945.1 - 0.16 11.9 5.4 2 8.4 0.3 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 KZN84945.1 - 2.1 8.2 9.9 9.3 6.1 0.2 3.3 3 0 0 3 3 3 0 C2H2-type zinc-finger domain MFS_2 PF13347.6 KZN84946.1 - 1e-09 37.5 9.6 1e-09 37.5 9.6 1.7 2 0 0 2 2 2 1 MFS/sugar transport protein PUCC PF03209.15 KZN84946.1 - 7.2e-05 22.0 3.0 0.00012 21.2 3.0 1.3 1 0 0 1 1 1 1 PUCC protein Na_H_Exchanger PF00999.21 KZN84947.1 - 2.8e-69 233.8 40.6 3.5e-69 233.4 40.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4396 PF14342.6 KZN84947.1 - 5.1 7.4 13.5 0.83 10.0 2.1 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4396) AA_permease_2 PF13520.6 KZN84948.1 - 3.1e-57 194.3 28.4 3.9e-57 194.0 28.4 1.1 1 0 0 1 1 1 1 Amino acid permease ADH_N PF08240.12 KZN84949.1 - 3.2e-28 97.8 0.7 5.6e-28 97.0 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN84949.1 - 6.6e-24 84.3 0.5 1.1e-23 83.6 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KZN84949.1 - 4.1e-05 24.7 0.1 6.4e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KZN84949.1 - 0.0019 17.6 0.2 0.0032 16.8 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KZN84949.1 - 0.037 13.3 0.9 0.055 12.8 0.9 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 KZN84949.1 - 2.5 7.5 8.0 0.056 12.9 1.2 1.8 2 1 0 2 2 2 0 short chain dehydrogenase WD40 PF00400.32 KZN84952.1 - 1.5e-29 101.6 17.7 2.9e-06 27.9 0.0 11.4 11 0 0 11 11 11 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN84952.1 - 1.6e-18 66.7 0.4 0.0062 16.8 0.0 8.7 3 2 5 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain HNH_2 PF13391.6 KZN84952.1 - 4.7e-13 49.1 0.3 1.1e-12 47.9 0.3 1.6 1 0 0 1 1 1 1 HNH endonuclease WD40_like PF17005.5 KZN84952.1 - 0.04 13.2 0.0 1.3 8.2 0.0 2.3 1 1 1 2 2 2 0 WD40-like domain PALB2_WD40 PF16756.5 KZN84952.1 - 0.057 12.3 0.0 3.5 6.5 0.0 2.8 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain PD40 PF07676.12 KZN84952.1 - 0.19 11.7 9.7 19 5.3 0.2 6.0 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat SNF2_N PF00176.23 KZN84953.1 - 6.8e-65 219.1 0.7 1.3e-64 218.1 0.7 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 KZN84953.1 - 3.2e-49 166.7 22.3 3.2e-49 166.7 22.3 4.4 4 0 0 4 4 4 1 DNA-binding domain Helicase_C PF00271.31 KZN84953.1 - 4.4e-19 68.8 0.0 1.2e-18 67.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KZN84953.1 - 7.9e-07 29.2 2.3 9e-07 29.0 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KZN84953.1 - 0.0019 18.0 0.0 0.0056 16.5 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KZN84953.1 - 0.03 13.5 0.9 0.19 10.9 0.0 2.7 3 1 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 DnaJ PF00226.31 KZN84954.1 - 8.6e-20 70.6 0.2 8.6e-20 70.6 0.2 2.2 2 0 0 2 2 2 1 DnaJ domain DUF4200 PF13863.6 KZN84954.1 - 0.52 10.7 14.1 0.1 13.0 9.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) RR_TM4-6 PF06459.12 KZN84954.1 - 2.8 7.7 10.1 0.17 11.7 4.8 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Inv-AAD PF18785.1 KZN84955.1 - 9e-46 154.9 0.0 1.2e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KZN84955.1 - 2.1e-10 40.4 0.0 7.8e-10 38.5 0.0 1.9 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 KZN84955.1 - 0.00036 20.5 0.0 0.00067 19.6 0.0 1.4 1 1 0 1 1 1 1 APOBEC-like N-terminal domain Stn1 PF10451.9 KZN84956.1 - 7.6e-12 44.7 0.1 2e-05 23.7 0.0 2.1 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 KZN84956.1 - 3.9e-05 23.6 0.0 0.04 13.9 0.0 2.3 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain PhyH PF05721.13 KZN84956.1 - 0.19 12.0 1.1 0.37 11.0 1.1 1.5 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) Mitofilin PF09731.9 KZN84956.1 - 1.5 7.6 8.4 2 7.2 8.4 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF3391 PF11871.8 KZN84956.1 - 7.6 7.1 8.3 6.5 7.3 4.8 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) Stc1 PF12898.7 KZN84958.1 - 5.9e-15 55.6 16.0 8.4e-15 55.1 16.0 1.2 1 0 0 1 1 1 1 Stc1 domain Pkinase PF00069.25 KZN84959.1 - 2e-57 194.6 0.0 3.2e-57 193.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN84959.1 - 1e-30 106.9 0.0 5.7e-29 101.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KZN84959.1 - 0.0017 17.3 0.0 0.0029 16.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KZN84959.1 - 0.097 11.6 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RNase_PH PF01138.21 KZN84960.1 - 2.5e-11 44.2 0.0 6.3e-11 42.9 0.0 1.7 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KZN84960.1 - 0.019 15.0 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Fmp27 PF10344.9 KZN84961.1 - 0.0093 14.1 0.0 0.012 13.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Pneumo_att_G PF05539.11 KZN84961.1 - 2.1 7.8 4.2 3.1 7.3 4.2 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Cytochrom_C PF00034.21 KZN84962.1 - 6e-14 53.0 0.1 9.4e-14 52.3 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KZN84962.1 - 4.2e-08 33.4 2.7 2.5e-07 30.9 2.7 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KZN84962.1 - 0.001 18.8 0.0 0.0021 17.7 0.0 1.6 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrome-c551 PF10643.9 KZN84962.1 - 0.017 14.7 0.1 0.02 14.5 0.1 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 ParB_C PF18064.1 KZN84963.1 - 0.059 13.5 0.0 0.24 11.6 0.0 2.1 1 0 0 1 1 1 0 Centromere-binding protein ParB C-terminal Baculo_PEP_C PF04513.12 KZN84963.1 - 0.27 11.3 2.3 0.63 10.1 0.2 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATE_C PF04377.15 KZN84964.1 - 4.2e-48 163.4 2.1 6.7e-48 162.7 2.1 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KZN84964.1 - 1.2e-21 76.8 3.3 2.7e-21 75.7 3.3 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 KZN84964.1 - 0.0024 18.0 0.4 0.0042 17.2 0.4 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NUDIX PF00293.28 KZN84965.1 - 1.1e-17 64.4 0.5 1.3e-17 64.1 0.5 1.1 1 0 0 1 1 1 1 NUDIX domain RNA_pol_A_bac PF01000.26 KZN84966.1 - 5.3e-30 104.1 0.0 8.2e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KZN84966.1 - 7.7e-14 50.9 0.0 1.1e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Calcipressin PF04847.12 KZN84967.1 - 1.7e-30 106.2 0.3 2.2e-30 105.8 0.3 1.1 1 0 0 1 1 1 1 Calcipressin Phage_cap_P2 PF05125.12 KZN84967.1 - 0.07 12.1 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 Phage major capsid protein, P2 family DUF4345 PF14248.6 KZN84968.1 - 0.013 15.4 0.5 0.019 14.9 0.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4345) AA_permease_2 PF13520.6 KZN84969.1 - 2.2e-75 254.1 36.4 2.9e-75 253.7 36.4 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN84969.1 - 2.2e-11 43.1 31.6 3.5e-11 42.4 31.6 1.2 1 0 0 1 1 1 1 Amino acid permease GrpE PF01025.19 KZN84971.1 - 6.1e-39 133.3 6.4 9.5e-39 132.7 6.4 1.3 1 0 0 1 1 1 1 GrpE DUF5454 PF17535.2 KZN84971.1 - 0.04 13.3 1.8 0.054 12.9 1.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5454) Rsd_AlgQ PF04353.13 KZN84971.1 - 0.16 12.0 1.7 0.68 9.9 0.5 2.0 1 1 1 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ tRNA-synt_2d PF01409.20 KZN84972.1 - 8.7e-48 162.9 0.1 4.1e-25 88.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KZN84972.1 - 2.3e-28 98.5 0.0 8.3e-28 96.7 0.0 2.0 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain Mito_carr PF00153.27 KZN84973.1 - 0.0019 18.0 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial carrier protein Mito_carr PF00153.27 KZN84974.1 - 7.7e-47 157.2 1.2 1.2e-17 63.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein COX6B PF02297.17 KZN84975.1 - 2.6e-18 66.0 7.5 3e-18 65.8 7.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.14 KZN84975.1 - 0.014 15.3 0.5 0.019 14.9 0.5 1.2 1 0 0 1 1 1 0 APOBEC-like C-terminal domain ketoacyl-synt PF00109.26 KZN84975.1 - 0.18 11.4 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain RRM_1 PF00076.22 KZN84976.1 - 1.1e-17 63.6 0.0 1.8e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KZN84976.1 - 0.0049 17.0 0.0 0.0076 16.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif Limkain-b1 PF11608.8 KZN84976.1 - 0.028 14.5 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 SRA1 PF07304.11 KZN84977.1 - 1.5e-14 54.0 0.0 1.5e-14 54.0 0.0 3.7 4 0 0 4 4 4 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.32 KZN84977.1 - 2e-09 37.9 5.3 0.87 10.6 0.1 6.6 6 0 0 6 6 6 3 WD domain, G-beta repeat Sec16_C PF12931.7 KZN84977.1 - 0.00087 19.0 0.1 0.0096 15.6 0.1 2.3 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 ANAPC4_WD40 PF12894.7 KZN84977.1 - 0.0012 19.0 0.8 0.019 15.3 0.1 3.2 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Prp18 PF02840.15 KZN84977.1 - 0.061 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Prp18 domain Pex14_N PF04695.13 KZN84978.1 - 4.5e-44 150.9 3.9 4.5e-44 150.9 3.9 2.7 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region PAPA-1 PF04795.12 KZN84979.1 - 1e-32 112.8 6.5 1e-32 112.8 6.5 3.7 4 1 0 4 4 4 1 PAPA-1-like conserved region Mus7 PF09462.10 KZN84981.1 - 6.4e-206 685.9 0.0 9e-206 685.4 0.0 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family Glyco_hydro_71 PF03659.14 KZN84982.1 - 5e-112 374.4 6.6 9.1e-67 225.5 0.1 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 71 AAA PF00004.29 KZN84983.1 - 9.5e-40 136.1 0.0 2.6e-37 128.2 0.0 3.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KZN84983.1 - 7.3e-09 35.3 0.1 1.9e-08 34.0 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KZN84983.1 - 3.6e-05 24.2 0.2 0.0019 18.6 0.1 3.2 1 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KZN84983.1 - 0.00013 21.8 0.0 0.00027 20.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KZN84983.1 - 0.00023 20.5 0.1 0.00069 18.9 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_22 PF13401.6 KZN84983.1 - 0.00042 20.6 0.9 0.021 15.1 0.1 3.1 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.6 KZN84983.1 - 0.00099 19.3 0.0 0.0054 16.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KZN84983.1 - 0.0013 18.7 0.0 0.004 17.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 KZN84983.1 - 0.0071 16.8 0.1 0.13 12.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KZN84983.1 - 0.0086 15.8 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.6 KZN84983.1 - 0.015 15.6 0.1 0.048 13.9 0.1 1.9 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KZN84983.1 - 0.02 14.3 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KZN84983.1 - 0.032 14.6 0.0 0.09 13.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KZN84983.1 - 0.057 13.5 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KZN84983.1 - 0.072 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KZN84983.1 - 0.074 13.6 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KZN84983.1 - 0.16 11.9 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE LIM_bind PF01803.16 KZN84984.1 - 5.5e-68 229.1 0.1 5.5e-68 229.1 0.1 4.5 2 1 2 4 4 4 1 LIM-domain binding protein cobW PF02492.19 KZN84985.1 - 9.8e-33 113.2 0.0 1.2e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KZN84985.1 - 1.8e-05 23.8 1.7 0.00022 20.3 1.7 2.0 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KZN84985.1 - 0.0068 16.5 0.0 0.017 15.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KZN84985.1 - 0.01 16.2 0.0 0.014 15.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KZN84985.1 - 0.019 15.5 0.0 0.029 14.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KZN84985.1 - 0.022 14.8 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KZN84985.1 - 0.026 13.7 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 KZN84985.1 - 0.036 13.8 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein PRK PF00485.18 KZN84985.1 - 0.06 13.1 0.1 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_21 PF13304.6 KZN84985.1 - 0.065 13.0 0.0 0.12 12.2 0.0 1.3 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KZN84985.1 - 0.15 12.5 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KZN84985.1 - 0.17 12.4 0.0 0.24 11.9 0.0 1.2 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 KZN84985.1 - 0.19 10.9 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin BING4CT PF08149.11 KZN84986.1 - 2.1e-38 130.0 0.0 5.4e-35 119.1 0.0 2.7 2 0 0 2 2 2 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 KZN84986.1 - 4.2e-09 36.6 0.1 0.4 11.0 0.0 5.8 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KZN84986.1 - 0.00028 21.6 0.7 0.31 12.0 0.0 4.3 3 2 1 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KZN84986.1 - 0.011 14.8 0.0 0.026 13.6 0.0 1.5 1 0 0 1 1 1 0 Coatomer WD associated region HNF_C PF09354.10 KZN84986.1 - 0.049 14.7 0.0 0.12 13.5 0.0 1.6 1 0 0 1 1 1 0 HNF3 C-terminal domain TTRAP PF14203.6 KZN84986.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein HPS3_N PF14761.6 KZN84986.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 RIBIOP_C PF04950.12 KZN84987.1 - 1.2e-106 356.5 0.0 1.9e-106 355.8 0.0 1.3 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KZN84987.1 - 5.2e-21 74.5 0.0 1.3e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain SNAP PF14938.6 KZN84988.1 - 9e-117 389.5 11.5 1e-116 389.3 11.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KZN84988.1 - 0.00026 21.2 15.2 0.054 13.8 0.5 4.4 2 1 3 5 5 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 KZN84988.1 - 0.0046 17.5 12.3 0.64 10.8 0.8 5.7 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KZN84988.1 - 0.0056 16.4 20.5 0.2 11.5 0.4 6.8 6 1 1 7 7 7 2 Tetratricopeptide repeat PhoU PF01895.19 KZN84988.1 - 0.0086 16.5 2.3 2.1 8.9 0.4 3.0 1 1 1 2 2 2 1 PhoU domain DUF2811 PF10929.8 KZN84988.1 - 0.0087 16.3 0.3 0.028 14.7 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2811) TPR_8 PF13181.6 KZN84988.1 - 0.014 15.5 15.8 0.029 14.5 0.4 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KZN84988.1 - 0.024 14.6 11.1 0.47 10.6 0.4 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat Hep_59 PF07052.11 KZN84988.1 - 0.051 14.3 0.9 0.13 13.0 0.9 1.7 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 NSF PF02071.20 KZN84988.1 - 0.063 14.0 17.5 5.8 8.2 0.2 7.3 7 1 1 8 8 7 0 Aromatic-di-Alanine (AdAR) repeat MIT PF04212.18 KZN84988.1 - 0.095 12.8 12.5 8.7 6.5 0.1 4.4 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain DFF40 PF09230.10 KZN84988.1 - 0.13 11.8 1.0 1.3 8.6 0.1 2.1 2 0 0 2 2 2 0 DNA fragmentation factor 40 kDa TPR_14 PF13428.6 KZN84988.1 - 0.69 10.9 11.6 4.5 8.4 1.8 4.7 2 1 4 6 6 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KZN84988.1 - 1.2 9.4 25.5 1 9.6 0.7 7.5 4 3 5 9 9 9 0 Tetratricopeptide repeat TPR_10 PF13374.6 KZN84988.1 - 3.7 7.5 0.0 3.7 7.5 0.0 4.0 5 1 0 5 5 5 0 Tetratricopeptide repeat Glu-tRNAGln PF02686.15 KZN84989.1 - 2.3e-11 43.8 0.2 1.1e-10 41.6 0.2 1.9 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit DUF726 PF05277.12 KZN84990.1 - 3.5e-123 410.9 1.5 4.5e-123 410.6 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 KZN84990.1 - 0.00023 21.3 0.0 0.00054 20.1 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Cutinase PF01083.22 KZN84990.1 - 0.089 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Cutinase EURL PF06937.11 KZN84990.1 - 0.79 9.1 3.9 0.29 10.5 1.1 1.6 2 0 0 2 2 2 0 EURL protein APH PF01636.23 KZN84992.1 - 3.7e-12 46.7 0.0 9.3e-12 45.4 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN84992.1 - 6.1e-05 22.7 0.0 0.0001 22.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase ADH_zinc_N_2 PF13602.6 KZN84993.1 - 5.7e-28 98.6 0.1 1e-27 97.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KZN84993.1 - 4.9e-15 55.7 0.1 9.1e-15 54.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KZN84993.1 - 0.00018 21.3 0.3 0.004 17.0 0.0 2.4 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Fe_hyd_lg_C PF02906.14 KZN84993.1 - 0.093 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Peptidase_M20 PF01546.28 KZN84994.1 - 6.9e-24 84.7 0.1 1e-23 84.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KZN84994.1 - 8.1e-11 41.8 0.0 1.8e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Alkyl_sulf_dimr PF14863.6 KZN84995.1 - 9.5e-58 194.6 0.0 1.6e-57 193.9 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Alkyl_sulf_C PF14864.6 KZN84995.1 - 9e-29 100.3 0.0 1.6e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B PF00753.27 KZN84995.1 - 5.9e-28 98.2 0.0 1.3e-27 97.2 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KZN84995.1 - 0.00017 21.2 0.0 0.00041 19.9 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain NatB_MDM20 PF09797.9 KZN84995.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit Fungal_trans PF04082.18 KZN84996.1 - 7.3e-18 64.5 1.3 1e-17 64.0 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN84996.1 - 0.24 11.5 5.4 0.52 10.5 5.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 KZN84996.1 - 0.24 11.9 4.8 0.57 10.7 4.8 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region UPF0506 PF11703.8 KZN84996.1 - 0.35 11.3 3.8 0.2 12.1 1.4 1.8 2 0 0 2 2 2 0 UPF0506 Alkyl_sulf_dimr PF14863.6 KZN84997.1 - 7.8e-58 194.9 0.0 1.3e-57 194.1 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.27 KZN84997.1 - 1.4e-34 119.8 1.1 2.4e-34 119.1 1.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Alkyl_sulf_C PF14864.6 KZN84997.1 - 2e-34 118.6 0.1 3.6e-34 117.8 0.1 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B_2 PF12706.7 KZN84997.1 - 8.6e-07 28.7 0.0 1.8e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TPR_19 PF14559.6 KZN84997.1 - 0.0012 19.3 0.3 0.0027 18.2 0.3 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 KZN84997.1 - 0.0027 18.3 1.1 0.0027 18.3 1.1 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KZN84997.1 - 0.015 15.0 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 TPR repeat Arylsulfotran_2 PF14269.6 KZN84998.1 - 3.2e-59 200.7 3.0 2.4e-58 197.9 3.8 1.8 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KZN84998.1 - 1.9e-16 60.0 2.4 8.7e-16 57.8 2.4 1.8 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ PF01011.21 KZN84998.1 - 0.0046 16.8 1.4 4.3 7.4 0.0 3.1 2 0 0 2 2 2 2 PQQ enzyme repeat DIOX_N PF14226.6 KZN85002.1 - 9.5e-14 52.2 0.0 2.3e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KZN85002.1 - 2.3e-06 28.0 0.1 1e-05 25.9 0.1 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 KZN85003.1 - 1e-30 106.9 34.7 5.7e-30 104.4 31.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LapA_dom PF06305.11 KZN85003.1 - 0.0049 16.7 0.3 0.021 14.7 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain Babuvirus_MP PF07234.11 KZN85003.1 - 0.09 12.9 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 Movement and RNA silencing protein Phage_holin_2_4 PF16082.5 KZN85003.1 - 0.12 12.1 0.6 0.5 10.1 0.1 2.3 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Hexapep PF00132.24 KZN85004.1 - 5.3e-07 29.1 6.7 0.007 16.0 2.7 3.2 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KZN85004.1 - 0.00024 21.5 0.0 0.00042 20.7 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 KZN85004.1 - 0.00058 18.9 0.6 0.003 16.6 0.6 2.0 1 1 0 1 1 1 1 L-fucokinase Glyco_hydro_114 PF03537.13 KZN85005.1 - 6.5e-82 274.3 6.4 1.2e-80 270.2 2.0 2.3 2 1 0 2 2 2 2 Glycoside-hydrolase family GH114 Metallophos PF00149.28 KZN85006.1 - 1.8e-10 41.7 0.0 2.6e-10 41.2 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KZN85006.1 - 7e-06 26.3 0.2 3e-05 24.3 0.1 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain FBPase_2 PF06874.11 KZN85006.1 - 0.21 9.8 0.2 0.31 9.3 0.2 1.3 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase C1_2 PF03107.16 KZN85007.1 - 0.022 15.1 0.3 0.051 13.9 0.3 1.6 1 0 0 1 1 1 0 C1 domain Glyco_hydro_31 PF01055.26 KZN85008.1 - 3.4e-141 471.4 1.4 4.8e-141 470.9 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KZN85008.1 - 6.7e-33 113.3 0.0 1.3e-32 112.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KZN85008.1 - 2.7e-05 24.4 0.5 0.00013 22.2 0.1 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like Glyco_hydro_75 PF07335.11 KZN85009.1 - 1.3e-43 149.1 0.4 2e-43 148.5 0.4 1.3 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 EB PF01683.18 KZN85009.1 - 3.3 8.1 11.6 0.85 10.0 7.7 1.9 2 0 0 2 2 2 0 EB module Ribosomal_L33 PF00471.20 KZN85010.1 - 2.8e-05 24.5 0.0 3.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 Myosin_tail_1 PF01576.19 KZN85011.1 - 0.0011 17.0 28.1 0.0011 17.0 28.1 2.8 2 1 0 2 2 2 1 Myosin tail Pkinase PF00069.25 KZN85013.1 - 5.4e-63 212.8 0.0 7.1e-63 212.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN85013.1 - 3.4e-33 115.0 0.0 4.6e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KZN85013.1 - 7.8e-07 28.7 0.0 1.2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KZN85013.1 - 0.00089 19.2 1.9 0.0016 18.4 0.2 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KZN85013.1 - 0.0035 16.7 0.1 0.0063 15.9 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KZN85013.1 - 0.012 14.4 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KZN85013.1 - 0.03 13.3 0.0 0.044 12.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KZN85014.1 - 6.1e-16 59.1 0.4 1.7e-15 57.6 0.4 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KZN85014.1 - 0.0034 16.8 0.0 0.36 10.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain RIO1 PF01163.22 KZN85014.1 - 0.021 14.4 0.0 1.5 8.4 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Choline_kinase PF01633.20 KZN85014.1 - 0.12 11.9 0.1 0.21 11.1 0.0 1.4 2 0 0 2 2 2 0 Choline/ethanolamine kinase Clr5 PF14420.6 KZN85016.1 - 2e-05 24.7 0.0 0.00022 21.4 0.0 2.4 2 0 0 2 2 2 1 Clr5 domain Sugar_tr PF00083.24 KZN85017.1 - 3.5e-79 266.8 26.7 4.2e-79 266.5 26.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN85017.1 - 1.4e-19 70.3 30.1 1.4e-19 70.3 30.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KZN85017.1 - 0.0017 17.3 5.5 0.0017 17.3 5.5 2.3 2 0 0 2 2 2 2 MFS_1 like family Phage_holin_2_4 PF16082.5 KZN85017.1 - 0.014 15.1 0.6 0.039 13.7 0.6 1.8 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Cellulase PF00150.18 KZN85018.1 - 7.5e-21 74.8 0.6 1e-20 74.4 0.6 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KZN85018.1 - 4.9e-05 22.6 0.1 8.6e-05 21.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KZN85018.1 - 0.0086 15.4 0.1 0.019 14.3 0.0 1.6 2 0 0 2 2 2 1 Beta-galactosidase TrkH PF02386.16 KZN85019.1 - 1.6e-125 419.4 4.2 1.9e-121 406.0 0.4 2.1 2 0 0 2 2 2 2 Cation transport protein Epimerase PF01370.21 KZN85020.1 - 1.2e-11 44.5 0.0 1.9e-11 43.9 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KZN85020.1 - 3.1e-07 30.5 0.0 4.9e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KZN85020.1 - 0.024 13.8 0.0 0.047 12.8 0.0 1.5 1 1 1 2 2 2 0 Male sterility protein KR PF08659.10 KZN85020.1 - 0.054 13.4 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 KR domain GDP_Man_Dehyd PF16363.5 KZN85020.1 - 0.079 12.3 0.5 0.12 11.8 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KZN85020.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain Cellulase PF00150.18 KZN85021.1 - 1.1e-13 51.3 2.1 1.1e-13 51.3 2.1 1.4 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Radical_SAM PF04055.21 KZN85021.1 - 0.052 13.9 0.0 0.32 11.4 0.0 2.1 2 0 0 2 2 2 0 Radical SAM superfamily EphA2_TM PF14575.6 KZN85021.1 - 5.2 8.0 0.0 5.2 8.0 0.0 3.4 4 1 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain HATPase_c PF02518.26 KZN85022.1 - 3.7e-18 66.1 0.0 9.9e-18 64.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KZN85022.1 - 1.2e-12 47.7 0.6 3.5e-12 46.2 0.6 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 KZN85022.1 - 3.5e-11 43.3 0.0 9e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PHY PF00360.20 KZN85022.1 - 5.4e-07 29.1 0.0 2e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 Phytochrome region GAF PF01590.26 KZN85022.1 - 0.0059 17.2 0.0 0.018 15.6 0.0 1.9 1 0 0 1 1 1 1 GAF domain HATPase_c_2 PF13581.6 KZN85022.1 - 0.01 15.8 0.1 0.023 14.7 0.1 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain PAS_2 PF08446.11 KZN85022.1 - 0.038 14.7 0.0 0.1 13.3 0.0 1.7 1 0 0 1 1 1 0 PAS fold GAF_2 PF13185.6 KZN85022.1 - 0.047 14.0 0.0 0.76 10.1 0.0 2.4 2 0 0 2 2 2 0 GAF domain HATPase_c_3 PF13589.6 KZN85022.1 - 0.079 12.8 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SNF2_N PF00176.23 KZN85023.1 - 2.9e-67 226.8 0.1 6.6e-66 222.4 0.1 2.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KZN85023.1 - 6.7e-16 58.6 0.0 2.9e-15 56.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KZN85023.1 - 3.8e-07 30.3 0.2 3.8e-07 30.3 0.2 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit BUD22 PF09073.10 KZN85023.1 - 3.3e-05 23.4 42.1 0.0005 19.5 18.6 2.4 2 0 0 2 2 2 2 BUD22 SDA1 PF05285.12 KZN85023.1 - 0.59 9.5 39.7 0.52 9.7 21.4 2.4 2 0 0 2 2 2 0 SDA1 DUF1387 PF07139.11 KZN85023.1 - 0.82 9.3 25.8 0.23 11.1 14.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) Nop14 PF04147.12 KZN85023.1 - 4.1 5.5 40.7 0.012 13.8 17.5 2.2 2 0 0 2 2 2 0 Nop14-like family TPP_enzyme_N PF02776.18 KZN85024.1 - 2.4e-41 141.2 0.2 2.8e-40 137.7 0.1 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KZN85024.1 - 1.4e-22 80.1 0.3 1.3e-21 77.0 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KZN85024.1 - 8e-08 32.1 0.0 2.3e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Peptidase_S78_2 PF14550.6 KZN85024.1 - 0.006 16.7 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative phage serine protease XkdF XFP_N PF09364.10 KZN85024.1 - 0.22 10.3 0.8 0.34 9.6 0.8 1.2 1 0 0 1 1 1 0 XFP N-terminal domain SIR2 PF02146.17 KZN85025.1 - 1.2e-39 136.0 0.0 6.1e-39 133.8 0.0 1.8 1 1 0 1 1 1 1 Sir2 family APG12 PF04110.13 KZN85027.1 - 3.8e-29 100.9 0.0 8.8e-29 99.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 KZN85027.1 - 0.0055 16.9 0.0 0.0073 16.5 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Pantoate_transf PF02548.15 KZN85028.1 - 1.5e-108 362.1 1.2 1.9e-108 361.8 1.2 1.1 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KZN85028.1 - 7.7e-07 28.8 0.4 1.3e-06 28.1 0.1 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF4861 PF16153.5 KZN85028.1 - 0.00029 19.9 0.0 0.00041 19.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4861) Dfp1_Him1_M PF08630.10 KZN85029.1 - 2.3e-40 137.7 0.0 6.7e-40 136.2 0.0 1.9 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 KZN85029.1 - 7.1e-21 74.1 0.1 1.4e-20 73.1 0.1 1.5 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.7 KZN85029.1 - 0.075 13.0 0.0 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 twin BRCT domain Peptidase_M24 PF00557.24 KZN85030.1 - 1.7e-50 171.6 0.0 2.5e-50 171.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KZN85030.1 - 1.9e-36 124.5 0.0 3.3e-36 123.7 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain RuBisCO_large PF00016.20 KZN85030.1 - 0.021 14.0 0.0 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Pyridox_ox_2 PF12900.7 KZN85031.1 - 2.4e-35 121.6 0.0 3.3e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ank_2 PF12796.7 KZN85032.1 - 5.9e-36 122.9 2.8 2.6e-12 47.2 0.0 9.0 7 2 1 8 8 8 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN85032.1 - 4.5e-31 106.8 2.3 8.4e-06 26.2 0.0 10.5 10 0 0 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KZN85032.1 - 4.3e-25 87.5 6.7 0.0024 18.2 0.0 10.0 10 0 0 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.30 KZN85032.1 - 9.6e-20 70.1 17.6 0.0002 21.6 0.0 10.8 11 0 0 11 11 11 6 Ankyrin repeat Ank_3 PF13606.6 KZN85032.1 - 4.1e-19 66.7 12.7 0.05 14.2 0.0 12.6 13 0 0 13 13 13 3 Ankyrin repeat Fanconi_A_N PF15865.5 KZN85033.1 - 0.026 13.9 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 Fanconi anaemia group A protein N terminus LAMTOR PF15454.6 KZN85034.1 - 3.6e-19 69.1 0.1 6.2e-19 68.4 0.1 1.3 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF2733 PF10813.8 KZN85034.1 - 0.35 10.7 0.9 1.3 8.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) DUF2011 PF09428.10 KZN85035.1 - 3.6e-33 113.7 1.1 1.4e-31 108.6 0.0 2.3 2 0 0 2 2 2 2 Fungal protein of unknown function (DUF2011) FAM196 PF15265.6 KZN85036.1 - 1.6 8.2 8.5 2 7.8 8.5 1.1 1 0 0 1 1 1 0 FAM196 family HemY_N PF07219.13 KZN85036.1 - 5.2 7.3 8.9 1.6 9.0 1.0 2.5 2 0 0 2 2 2 0 HemY protein N-terminus Tht1 PF04163.12 KZN85037.1 - 7.3e-05 21.7 8.3 0.0002 20.3 8.3 1.8 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein Baculo_PEP_C PF04513.12 KZN85037.1 - 0.012 15.6 5.2 0.012 15.6 5.2 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1759 PF03564.15 KZN85037.1 - 0.073 13.0 2.2 0.29 11.0 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) DUF4305 PF14146.6 KZN85037.1 - 0.079 13.2 0.3 0.2 11.9 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4305) Trns_repr_metal PF02583.17 KZN85037.1 - 1.5 9.3 6.0 0.62 10.5 1.0 2.9 2 1 1 3 3 3 0 Metal-sensitive transcriptional repressor RNA_polI_A14 PF08203.11 KZN85037.1 - 2.7 8.8 7.8 1.2 10.0 3.4 2.6 2 1 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 DUF3584 PF12128.8 KZN85037.1 - 7.1 4.0 24.6 10 3.5 23.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 KZN85037.1 - 7.5 6.6 9.9 14 5.8 1.3 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 KZN85037.1 - 8.5 6.2 19.0 1.3 8.9 6.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF724) Ribosomal_L6 PF00347.23 KZN85039.1 - 1.8e-21 76.6 0.0 2e-09 38.0 0.0 2.7 2 1 0 2 2 2 2 Ribosomal protein L6 Inositol_P PF00459.25 KZN85040.1 - 2.3e-51 174.9 0.2 3.7e-51 174.2 0.2 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family VHS PF00790.19 KZN85041.1 - 1.6e-25 89.6 0.0 4.3e-25 88.2 0.0 1.7 1 0 0 1 1 1 1 VHS domain ENTH PF01417.20 KZN85041.1 - 0.00028 20.9 0.0 0.00076 19.5 0.0 1.7 1 0 0 1 1 1 1 ENTH domain GAT PF03127.14 KZN85041.1 - 0.0019 18.5 0.1 0.0045 17.3 0.1 1.8 1 1 0 1 1 1 1 GAT domain Dexa_ind PF15198.6 KZN85041.1 - 0.01 15.9 0.1 0.35 11.0 0.1 2.3 2 0 0 2 2 2 0 Dexamethasone-induced DUF4598 PF15370.6 KZN85041.1 - 0.15 12.6 2.9 0.1 13.1 0.4 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4598) ABM PF03992.16 KZN85042.1 - 0.1 12.7 0.3 2.4 8.4 0.1 2.7 2 1 0 2 2 2 0 Antibiotic biosynthesis monooxygenase Flavoprotein PF02441.19 KZN85043.1 - 3.8e-12 46.2 0.0 7e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Flavoprotein Abhydrolase_6 PF12697.7 KZN85043.1 - 0.00019 22.2 0.3 0.00019 22.2 0.3 2.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KZN85043.1 - 0.00063 19.1 0.0 0.083 12.1 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KZN85043.1 - 0.0024 17.5 0.1 1.2 8.7 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Lipase_3 PF01764.25 KZN85043.1 - 0.0034 17.2 0.0 0.0066 16.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) RNA_POL_M_15KD PF02150.16 KZN85044.1 - 0.0012 18.7 0.2 0.0026 17.6 0.2 1.6 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 KZN85044.1 - 0.016 15.2 0.1 0.027 14.5 0.1 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain MFS_1 PF07690.16 KZN85045.1 - 1.8e-42 145.5 48.3 1.8e-42 145.5 48.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN85045.1 - 2.3e-15 56.4 14.9 2.3e-15 56.4 14.9 3.2 3 0 0 3 3 3 1 Sugar (and other) transporter DUF3632 PF12311.8 KZN85047.1 - 9.3e-27 94.6 0.0 1.3e-26 94.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Bradykinin PF06753.12 KZN85047.1 - 0.13 11.9 0.2 0.3 10.8 0.2 1.5 1 0 0 1 1 1 0 Bradykinin Antifungal_prot PF11402.8 KZN85048.1 - 4.1e-23 81.3 11.5 5.2e-23 81.0 11.5 1.1 1 0 0 1 1 1 1 Antifungal protein Tannase PF07519.11 KZN85049.1 - 9.2e-119 397.4 0.8 1.4e-118 396.8 0.8 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KZN85049.1 - 0.011 15.0 0.0 0.076 12.3 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 MFS_1 PF07690.16 KZN85051.1 - 1.5e-06 27.4 37.8 1.5e-06 27.4 37.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily GWT1 PF06423.12 KZN85051.1 - 1.2 9.2 3.9 1.9 8.6 3.5 1.5 1 1 0 1 1 1 0 GWT1 FolB PF02152.18 KZN85052.1 - 7.6e-26 90.9 0.0 3.7e-19 69.3 0.0 2.5 2 0 0 2 2 2 2 Dihydroneopterin aldolase PTR2 PF00854.21 KZN85054.1 - 6.8e-75 252.4 5.9 1.5e-74 251.2 5.9 1.5 1 1 0 1 1 1 1 POT family DUF1435 PF07256.12 KZN85054.1 - 0.05 13.7 1.1 0.1 12.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) CPBP PF02517.16 KZN85054.1 - 5.7 7.4 7.3 1.4 9.3 2.2 2.5 2 0 0 2 2 2 0 CPBP intramembrane metalloprotease Abhydrolase_3 PF07859.13 KZN85055.1 - 2.3e-37 128.9 0.0 3.1e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KZN85055.1 - 4.2e-05 22.6 0.3 0.00012 21.1 0.3 1.6 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KZN85055.1 - 0.0081 15.7 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 KZN85055.1 - 0.023 14.2 0.1 0.035 13.6 0.1 1.1 1 0 0 1 1 1 0 Esterase PHB depolymerase Fungal_trans PF04082.18 KZN85056.1 - 5.5e-13 48.5 0.1 9e-13 47.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gpi16 PF04113.14 KZN85057.1 - 2.6e-245 815.2 0.0 3.2e-245 814.9 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component LUC7 PF03194.15 KZN85058.1 - 5.5e-74 249.0 2.9 6.5e-74 248.8 2.9 1.0 1 0 0 1 1 1 1 LUC7 N_terminus MCPsignal PF00015.21 KZN85058.1 - 0.013 15.3 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TelA PF05816.11 KZN85058.1 - 0.02 14.0 0.3 0.031 13.4 0.3 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) Syntaxin_2 PF14523.6 KZN85058.1 - 0.034 14.5 2.0 0.073 13.5 2.0 1.5 1 0 0 1 1 1 0 Syntaxin-like protein DegS PF05384.11 KZN85058.1 - 0.044 13.3 1.8 0.65 9.5 0.2 2.3 1 1 1 2 2 2 0 Sensor protein DegS DASH_Duo1 PF08651.10 KZN85058.1 - 0.11 12.3 0.1 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 DASH complex subunit Duo1 Glutaredoxin2_C PF04399.13 KZN85058.1 - 0.12 12.2 0.1 0.57 10.0 0.0 2.0 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain Prefoldin PF02996.17 KZN85058.1 - 0.29 11.0 1.3 2 8.4 0.2 2.3 2 0 0 2 2 2 0 Prefoldin subunit Occludin_ELL PF07303.13 KZN85058.1 - 0.85 10.4 2.9 4.3 8.1 0.1 2.9 2 1 0 2 2 2 0 Occludin homology domain XhlA PF10779.9 KZN85058.1 - 1.2 9.4 4.3 1.3 9.3 0.6 2.2 2 0 0 2 2 2 0 Haemolysin XhlA SPOC PF07744.13 KZN85059.1 - 3.7e-25 88.6 0.0 6.1e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 KZN85059.1 - 1.4e-23 83.5 1.0 1.4e-23 83.5 1.0 2.1 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 KZN85059.1 - 2e-10 40.4 12.9 3.5e-10 39.6 12.9 1.4 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.6 KZN85059.1 - 0.026 14.9 0.5 0.026 14.9 0.5 2.4 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx PHD_2 PF13831.6 KZN85059.1 - 0.066 12.8 5.6 0.11 12.0 5.6 1.4 1 0 0 1 1 1 0 PHD-finger MPLKIP PF15502.6 KZN85059.1 - 0.33 11.2 1.9 1.4 9.2 1.9 2.2 1 0 0 1 1 1 0 M-phase-specific PLK1-interacting protein CEBP_ZZ PF16366.5 KZN85059.1 - 0.49 10.7 4.5 0.95 9.7 4.5 1.4 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Arabinose_trans PF04602.12 KZN85060.1 - 0.029 13.2 0.6 0.038 12.8 0.6 1.1 1 0 0 1 1 1 0 Mycobacterial cell wall arabinan synthesis protein SlyX PF04102.12 KZN85060.1 - 5.5 7.7 8.9 2.1 9.0 4.9 2.3 1 1 1 2 2 2 0 SlyX FF PF01846.19 KZN85061.1 - 1e-12 48.0 7.6 9.6e-11 41.7 0.2 3.3 3 0 0 3 3 3 2 FF domain WW PF00397.26 KZN85061.1 - 0.0022 18.0 1.1 0.0022 18.0 1.1 3.1 3 0 0 3 3 3 1 WW domain VGLL4 PF15245.6 KZN85061.1 - 0.034 14.2 1.7 0.079 13.0 0.5 2.1 2 0 0 2 2 2 0 Transcription cofactor vestigial-like protein 4 Proteasome PF00227.26 KZN85062.1 - 1.4e-61 207.3 0.2 1.7e-61 207.1 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KZN85062.1 - 4.8e-13 48.5 0.7 8.9e-13 47.7 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 KZN85062.1 - 0.018 15.2 0.5 0.049 13.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Nitrate_red_gam PF02665.14 KZN85062.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit SHE3 PF17078.5 KZN85063.1 - 0.0016 18.2 2.7 0.002 17.9 2.7 1.1 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 MYO10_CC PF16735.5 KZN85063.1 - 0.0069 16.5 1.8 0.0069 16.5 1.8 2.3 1 1 2 3 3 3 1 Unconventional myosin-X coiled coil domain Ribosomal_L26 PF16906.5 KZN85063.1 - 0.058 13.9 0.1 0.079 13.4 0.1 1.3 1 0 0 1 1 1 0 Ribosomal proteins L26 eukaryotic, L24P archaeal NAD_binding_10 PF13460.6 KZN85065.1 - 2.5e-07 30.8 0.0 3.6e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KZN85065.1 - 2.6e-07 30.3 0.0 8e-07 28.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HIM1 PF08732.10 KZN85065.1 - 9.2e-07 28.5 0.0 1.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 HIM1 NmrA PF05368.13 KZN85065.1 - 0.0012 18.4 0.0 0.0023 17.5 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KZN85065.1 - 0.0014 19.0 0.1 0.0095 16.4 0.1 2.0 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DUF1471 PF07338.13 KZN85065.1 - 0.0049 16.8 0.3 0.0099 15.8 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1471) NAD_binding_4 PF07993.12 KZN85065.1 - 0.024 13.8 0.2 1.5 8.0 0.1 2.2 1 1 0 2 2 2 0 Male sterility protein Ank PF00023.30 KZN85066.1 - 3.7e-21 74.6 1.5 0.0016 18.8 0.0 6.7 6 1 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.7 KZN85066.1 - 9.1e-18 64.6 0.0 3.6e-07 30.7 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN85066.1 - 1.5e-13 50.9 2.0 0.0033 18.0 0.1 6.2 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN85066.1 - 1.4e-12 46.6 2.3 0.015 15.8 0.1 7.4 7 1 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 KZN85066.1 - 5.7e-06 26.5 2.2 0.011 16.1 0.0 4.7 6 0 0 6 6 6 1 Ankyrin repeats (many copies) F-box-like PF12937.7 KZN85066.1 - 0.0056 16.6 0.4 0.011 15.6 0.4 1.5 1 0 0 1 1 1 1 F-box-like Acyl-CoA_dh_1 PF00441.24 KZN85067.1 - 6.4e-33 114.1 0.5 1.1e-32 113.3 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KZN85067.1 - 9.7e-24 83.4 0.1 1.6e-23 82.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KZN85067.1 - 1.6e-16 60.9 0.1 7.8e-16 58.7 0.0 2.3 2 2 1 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KZN85067.1 - 2.2e-05 24.8 0.3 3.5e-05 24.1 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RicinB_lectin_2 PF14200.6 KZN85069.1 - 7.6e-11 42.6 2.4 1.3e-06 29.0 0.6 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like FB_lectin PF07367.11 KZN85070.1 - 1.8e-40 138.1 0.4 2.1e-40 137.9 0.4 1.0 1 0 0 1 1 1 1 Fungal fruit body lectin zf-C2H2 PF00096.26 KZN85071.1 - 0.0012 19.2 38.6 2.6 8.7 1.2 8.0 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KZN85071.1 - 0.82 10.7 30.2 4.5 8.4 0.3 7.8 6 1 1 7 7 7 0 C2H2-type zinc finger zf-FCS PF06467.14 KZN85071.1 - 1.4 8.9 9.3 0.3 11.0 0.2 4.0 4 0 0 4 4 4 0 MYM-type Zinc finger with FCS sequence motif FAD_binding_1 PF00667.20 KZN85072.1 - 1.2e-61 208.1 0.0 2.1e-61 207.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain POR PF01558.18 KZN85072.1 - 1.7e-10 41.3 0.3 4e-10 40.0 0.3 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase NAD_binding_1 PF00175.21 KZN85072.1 - 2.6e-09 37.7 0.0 7.9e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 KZN85072.1 - 5.1e-06 26.7 0.1 1.3e-05 25.4 0.1 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 KZN85072.1 - 0.0012 18.7 0.6 0.0046 16.8 0.1 2.3 2 0 0 2 2 2 1 Transketolase, C-terminal domain FtsJ PF01728.19 KZN85073.1 - 3.1e-63 213.1 0.0 4e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase DEAD PF00270.29 KZN85074.1 - 1.2e-44 152.1 0.1 2.3e-44 151.3 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KZN85074.1 - 1.7e-27 95.9 0.1 2.3e-26 92.3 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KZN85074.1 - 0.014 15.7 0.3 0.049 13.9 0.3 2.0 1 1 0 1 1 1 0 AAA domain Presenilin PF01080.17 KZN85074.1 - 1.1 7.9 6.6 2 7.1 6.6 1.4 1 0 0 1 1 1 0 Presenilin DUF4228 PF14009.6 KZN85074.1 - 1.7 9.0 6.7 3 8.2 1.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) Tim54 PF11711.8 KZN85074.1 - 3.5 6.3 10.1 3 6.5 7.5 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 MecA PF05389.12 KZN85074.1 - 7.8 6.1 10.5 5.5 6.5 7.0 2.3 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) RR_TM4-6 PF06459.12 KZN85074.1 - 9 6.0 15.3 1.3 8.8 9.7 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF1688 PF07958.11 KZN85075.1 - 1.8e-166 554.0 0.0 2.1e-166 553.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) DUF4326 PF14216.6 KZN85076.1 - 0.037 14.7 2.7 7.7 7.3 0.1 4.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4326) DNA_pol_phi PF04931.13 KZN85076.1 - 8.2 4.4 5.0 9.9 4.1 5.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi 4HBT PF03061.22 KZN85077.1 - 1.9e-08 34.5 0.1 4.6e-08 33.3 0.0 1.7 2 0 0 2 2 2 1 Thioesterase superfamily HECT PF00632.25 KZN85079.1 - 1.8e-75 254.3 0.0 3.1e-75 253.5 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HEAT PF02985.22 KZN85079.1 - 0.00081 19.5 1.6 0.21 11.9 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 KZN85079.1 - 0.0021 18.5 0.1 0.16 12.5 0.0 3.1 2 0 0 2 2 2 1 HEAT-like repeat Adaptin_N PF01602.20 KZN85079.1 - 0.21 10.1 2.7 0.18 10.4 0.1 2.2 2 1 0 2 2 2 0 Adaptin N terminal region Arm PF00514.23 KZN85079.1 - 0.47 10.6 10.4 18 5.6 0.1 5.8 5 1 1 6 6 6 0 Armadillo/beta-catenin-like repeat CTP_transf_like PF01467.26 KZN85080.1 - 1.1e-26 93.7 0.0 1.5e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like SIS PF01380.22 KZN85081.1 - 3.4e-14 52.8 0.0 4.8e-13 49.1 0.0 2.2 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.6 KZN85081.1 - 1.5e-06 28.3 0.0 0.0004 20.4 0.0 2.3 1 1 1 2 2 2 2 SIS domain Ubie_methyltran PF01209.18 KZN85082.1 - 4.1e-81 271.7 0.0 5.6e-81 271.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KZN85082.1 - 2.1e-16 60.4 0.0 4.3e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN85082.1 - 1e-14 54.9 0.0 2.2e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN85082.1 - 3.1e-11 43.9 0.0 5.8e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN85082.1 - 4.2e-11 42.9 0.0 6.1e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN85082.1 - 6.3e-06 26.1 0.0 9.9e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KZN85082.1 - 0.0071 16.2 0.0 0.053 13.4 0.0 2.2 2 1 0 2 2 2 1 Hypothetical methyltransferase AA_permease PF00324.21 KZN85083.1 - 3.4e-106 355.7 42.9 3.9e-106 355.5 42.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KZN85083.1 - 7.6e-35 120.6 47.3 8.8e-35 120.3 47.3 1.0 1 0 0 1 1 1 1 Amino acid permease Fungal_trans PF04082.18 KZN85084.1 - 3e-13 49.4 0.0 4.3e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN85084.1 - 5.5e-05 23.2 8.9 9.7e-05 22.4 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KZN85085.1 - 6.7e-89 298.8 12.2 8.2e-89 298.5 12.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN85085.1 - 2.3e-30 105.8 42.2 3.7e-24 85.3 22.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KZN85085.1 - 0.0038 15.7 0.5 0.0038 15.7 0.5 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KZN85085.1 - 0.18 10.0 5.7 0.033 12.5 1.0 2.1 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF3792 PF12670.7 KZN85085.1 - 5.7 7.1 27.8 0.22 11.7 7.7 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3792) AnmK PF03702.14 KZN85086.1 - 1.4e-76 258.0 0.0 1.7e-76 257.8 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase NAGidase PF07555.13 KZN85087.1 - 4.9e-101 337.9 2.4 7.6e-101 337.3 1.0 1.9 1 1 1 2 2 2 1 beta-N-acetylglucosaminidase Glyco_hydro_20b PF02838.15 KZN85087.1 - 5.1e-22 79.0 0.1 1.1e-21 77.9 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_67N PF03648.14 KZN85087.1 - 0.0074 16.6 0.1 0.017 15.4 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Ig_mannosidase PF17753.1 KZN85088.1 - 1.8e-17 62.9 0.0 2.9e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Ig-fold domain Ig_GlcNase PF18368.1 KZN85088.1 - 0.023 14.9 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 Exo-beta-D-glucosaminidase Ig-fold domain Amino_oxidase PF01593.24 KZN85089.1 - 3.8e-62 211.1 0.8 1.5e-61 209.1 0.8 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KZN85089.1 - 1.9e-09 37.6 0.1 5.1e-09 36.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KZN85089.1 - 0.0002 20.7 0.3 0.027 13.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KZN85089.1 - 0.0011 18.4 0.3 0.21 10.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KZN85089.1 - 0.0026 17.2 0.3 0.012 15.0 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KZN85089.1 - 0.0029 16.9 0.1 0.022 14.0 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KZN85089.1 - 0.011 16.3 0.5 0.21 12.2 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KZN85089.1 - 0.015 14.6 0.4 0.035 13.4 0.4 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KZN85089.1 - 0.016 14.3 0.3 0.041 13.0 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KZN85089.1 - 0.019 14.1 0.0 0.071 12.2 0.2 1.8 2 1 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 KZN85089.1 - 0.026 13.2 0.3 0.31 9.7 0.2 2.4 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 KZN85089.1 - 0.083 12.1 0.2 0.25 10.6 0.1 1.8 2 0 0 2 2 2 0 Thi4 family DAO PF01266.24 KZN85089.1 - 0.12 12.0 1.6 0.3 10.6 1.6 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase ThiF PF00899.21 KZN85089.1 - 0.15 11.4 0.1 0.25 10.7 0.1 1.2 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.20 KZN85089.1 - 0.16 12.1 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Fungal_trans_2 PF11951.8 KZN85090.1 - 0.0016 17.4 3.6 0.0042 16.0 3.6 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Y_phosphatase3 PF13350.6 KZN85091.1 - 9.5e-56 189.4 0.0 1.1e-55 189.2 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KZN85091.1 - 8.8e-06 25.4 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KZN85091.1 - 0.0049 16.5 0.0 0.0081 15.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KZN85091.1 - 0.0066 16.6 0.0 0.0098 16.0 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Myotub-related PF06602.14 KZN85091.1 - 0.0069 15.4 0.0 0.0097 14.9 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain NUDIX PF00293.28 KZN85092.1 - 8.7e-10 38.7 0.0 1e-09 38.5 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KZN85092.1 - 0.0064 16.5 0.0 0.024 14.6 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain E1_dh PF00676.20 KZN85093.1 - 7.6e-90 300.9 0.0 9.2e-90 300.6 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KZN85093.1 - 1.5e-05 24.8 0.1 0.00034 20.4 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Ish1 PF10281.9 KZN85093.1 - 0.0067 16.7 0.2 0.013 15.8 0.2 1.5 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein XFP_N PF09364.10 KZN85093.1 - 0.038 12.8 0.0 0.069 11.9 0.0 1.4 1 0 0 1 1 1 0 XFP N-terminal domain DXP_synthase_N PF13292.6 KZN85093.1 - 0.12 11.6 0.0 0.4 9.8 0.0 1.7 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Spherulin4 PF12138.8 KZN85094.1 - 1.1e-48 166.0 1.5 1.2e-48 165.8 1.5 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 zf-RING_4 PF14570.6 KZN85095.1 - 1.8e-19 69.2 13.5 3.6e-19 68.3 13.5 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KZN85095.1 - 3.2e-06 26.9 6.8 5.6e-06 26.1 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KZN85095.1 - 0.00017 21.3 0.0 0.00037 20.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 KZN85095.1 - 0.00083 19.6 10.6 0.0016 18.7 10.6 1.5 1 0 0 1 1 1 1 Ring finger domain Baculo_IE-1 PF05290.11 KZN85095.1 - 0.0072 16.3 4.8 0.013 15.4 4.8 1.3 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 KZN85095.1 - 0.07 13.0 8.5 0.5 10.3 8.7 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KZN85095.1 - 0.11 12.4 12.2 0.22 11.4 12.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KZN85095.1 - 0.8 9.7 11.7 1.5 8.9 11.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KZN85095.1 - 1.1 9.4 10.1 2.3 8.3 10.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger DZR PF12773.7 KZN85095.1 - 6.1 7.0 10.6 80 3.4 10.6 2.4 1 1 0 1 1 1 0 Double zinc ribbon Rtf2 PF04641.12 KZN85095.1 - 7 5.9 16.3 0.032 13.6 2.4 2.7 2 0 0 2 2 2 0 Rtf2 RING-finger Complex1_30kDa PF00329.19 KZN85096.1 - 2.6e-45 154.0 0.0 3.7e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF3817 PF12823.7 KZN85096.1 - 0.19 12.6 0.0 0.33 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3817) BUD22 PF09073.10 KZN85097.1 - 1.5e-102 344.2 19.2 1.7e-102 344.0 19.2 1.0 1 0 0 1 1 1 1 BUD22 DUF4690 PF15756.5 KZN85097.1 - 1.2 9.8 3.4 3.3 8.4 3.4 1.7 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Fungal_trans PF04082.18 KZN85098.1 - 6.3e-25 87.7 0.1 1.1e-24 86.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN85098.1 - 2.1e-05 24.5 10.8 4.9e-05 23.4 10.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Shikimate_DH PF01488.20 KZN85099.1 - 2.6e-05 24.3 0.0 0.0012 18.9 0.0 2.4 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pro_dh PF01619.18 KZN85100.1 - 5.4e-65 219.8 0.1 6.8e-65 219.5 0.1 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Aldedh PF00171.22 KZN85101.1 - 6.6e-108 361.2 0.0 7.9e-108 360.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AP_endonuc_2 PF01261.24 KZN85102.1 - 1.7e-39 135.5 0.0 2.2e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel 6PGD PF00393.19 KZN85103.1 - 8.8e-82 274.7 0.0 1.1e-81 274.4 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KZN85103.1 - 3.4e-36 124.8 0.5 7.4e-36 123.7 0.1 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KZN85103.1 - 2.8e-05 24.1 0.1 4.6e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KZN85103.1 - 0.0005 19.5 0.1 0.00092 18.6 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KZN85103.1 - 0.0052 17.3 0.0 0.012 16.2 0.0 1.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 KZN85103.1 - 0.029 14.3 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 KZN85103.1 - 0.03 13.9 0.1 0.09 12.3 0.1 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PNP_UDP_1 PF01048.20 KZN85104.1 - 6.3e-41 140.2 0.2 7.7e-41 139.9 0.2 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DUF747 PF05346.11 KZN85105.1 - 4.8e-118 394.3 2.5 6.2e-118 393.9 2.5 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family KCH PF16944.5 KZN85106.1 - 5.9e-101 337.5 4.4 7.1e-101 337.2 4.4 1.1 1 0 0 1 1 1 1 Fungal potassium channel adh_short PF00106.25 KZN85107.1 - 2.6e-08 33.6 0.0 1.5e-07 31.1 0.0 2.1 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KZN85107.1 - 0.0014 18.6 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KZN85107.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase p450 PF00067.22 KZN85110.1 - 1.1e-76 258.5 0.0 1.5e-76 258.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 KZN85111.1 - 1.4e-06 28.3 5.8 2.5e-06 27.5 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N_2 PF13409.6 KZN85112.1 - 3.8e-12 46.3 0.1 9.7e-12 45.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KZN85112.1 - 2.7e-11 43.7 0.0 4.9e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KZN85112.1 - 3.9e-10 39.9 0.0 6.1e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KZN85112.1 - 2.1e-06 27.9 0.2 4.9e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KZN85112.1 - 3.1e-06 27.3 0.0 6.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KZN85112.1 - 0.036 14.1 0.0 0.064 13.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FAA_hydrolase PF01557.18 KZN85113.1 - 6.5e-55 186.2 0.0 8.6e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KZN85113.1 - 4.2e-31 107.3 0.1 6.7e-31 106.6 0.1 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal HgmA PF04209.13 KZN85114.1 - 1.5e-210 699.3 0.2 1.7e-210 699.1 0.2 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase TPR_17 PF13431.6 KZN85115.1 - 0.073 13.5 0.1 3.9 8.1 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyoxalase PF00903.25 KZN85116.1 - 4.2e-20 72.2 0.5 3.5e-15 56.3 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KZN85116.1 - 7.2e-13 48.8 0.1 2.9e-05 24.3 0.0 2.6 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 KZN85116.1 - 1.4e-06 28.6 0.1 3.6e-05 24.0 0.1 2.3 1 1 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 KZN85116.1 - 2.3e-06 27.9 0.3 0.13 12.4 0.2 3.4 3 1 0 3 3 3 2 Glyoxalase-like domain DUF4844 PF16133.5 KZN85116.1 - 0.1 13.1 0.1 0.41 11.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4844) zf-CHY PF05495.12 KZN85117.1 - 1.1e-11 45.1 10.4 1.1e-11 45.1 10.4 3.6 2 1 0 2 2 2 1 CHY zinc finger zf-CCCH PF00642.24 KZN85117.1 - 0.0029 17.5 2.7 0.0029 17.5 2.7 2.5 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zinc_ribbon_15 PF17032.5 KZN85117.1 - 0.0067 17.2 0.1 0.0067 17.2 0.1 3.4 3 0 0 3 3 3 1 zinc-ribbon family zf_CCCH_4 PF18345.1 KZN85117.1 - 0.0079 16.2 3.3 0.0079 16.2 3.3 2.8 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_2 PF14608.6 KZN85117.1 - 0.24 11.9 3.0 0.67 10.5 3.0 1.8 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 KZN85117.1 - 2.4 8.1 7.0 0.54 10.1 2.9 2.2 2 0 0 2 2 2 0 CCCH-type zinc finger DUF3295 PF11702.8 KZN85118.1 - 2e-192 641.0 24.7 2.3e-192 640.8 24.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 KZN85118.1 - 2.3e-12 46.5 1.9 6.2e-12 45.1 1.9 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Cpn60_TCP1 PF00118.24 KZN85120.1 - 5.5e-156 520.0 3.3 6.2e-156 519.8 3.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Chromo_shadow PF01393.19 KZN85121.1 - 4e-18 65.3 2.7 4.9e-15 55.4 0.1 2.3 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 KZN85121.1 - 4.3e-10 39.4 1.6 4.3e-10 39.4 1.6 1.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain MAJIN PF15077.6 KZN85121.1 - 1.4 8.7 6.1 0.2 11.4 2.1 1.6 2 0 0 2 2 2 0 Membrane-anchored junction protein CDC27 PF09507.10 KZN85121.1 - 1.6 8.1 17.3 0.24 10.8 2.9 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 RR_TM4-6 PF06459.12 KZN85121.1 - 4.3 7.1 14.4 3.3 7.5 1.8 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 FAM176 PF14851.6 KZN85121.1 - 6.4 6.4 11.6 0.32 10.7 4.3 2.1 2 0 0 2 2 2 0 FAM176 family RPA43_OB PF17875.1 KZN85121.1 - 8.9 7.0 9.3 2.4 8.8 2.8 2.2 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Rap1_C PF11626.8 KZN85122.1 - 6e-22 77.5 0.0 1.6e-21 76.2 0.0 1.7 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 KZN85122.1 - 7.6e-17 61.3 0.3 1.8e-16 60.1 0.0 1.8 2 0 0 2 2 2 1 Rap1 Myb domain BRCT_2 PF16589.5 KZN85122.1 - 1.7e-10 41.1 0.0 2.7e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DHHC PF01529.20 KZN85123.1 - 2.5e-30 105.3 6.8 2.5e-30 105.3 6.8 2.0 3 0 0 3 3 3 1 DHHC palmitoyltransferase Atx10homo_assoc PF09759.9 KZN85124.1 - 2.4e-31 107.7 0.3 7.1e-31 106.2 0.1 1.9 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Mt_ATP-synt_B PF05405.14 KZN85125.1 - 0.18 11.4 0.0 0.22 11.2 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) zf-RING_2 PF13639.6 KZN85126.1 - 1.3e-08 35.1 2.6 1.9e-08 34.5 2.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KZN85126.1 - 3.8e-06 27.1 3.3 2.9e-05 24.3 3.4 2.0 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KZN85126.1 - 0.00053 20.0 6.4 0.00086 19.3 6.4 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KZN85126.1 - 0.00091 19.2 0.6 0.0014 18.6 0.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KZN85126.1 - 0.0057 16.5 4.1 0.02 14.7 3.8 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 KZN85126.1 - 0.0064 16.7 0.3 0.015 15.6 0.3 1.6 1 0 0 1 1 1 1 zinc-ribbon zf-C3HC4 PF00097.25 KZN85126.1 - 0.025 14.4 0.9 0.044 13.7 0.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KZN85126.1 - 0.029 14.1 1.2 0.048 13.4 1.2 1.4 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 KZN85126.1 - 0.41 10.5 2.3 2.8 7.9 2.3 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Putative_PNPOx PF01243.20 KZN85127.1 - 5.9e-10 39.2 0.0 6.4e-05 23.1 0.0 2.8 2 1 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.24 KZN85127.1 - 0.00042 20.6 0.0 0.0015 18.8 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NTP_transferase PF00483.23 KZN85129.1 - 3.8e-31 108.6 0.0 5.3e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KZN85129.1 - 4.7e-09 36.8 0.0 7.2e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 KZN85129.1 - 4.8e-09 35.6 3.8 1.5e-06 27.7 0.1 3.4 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) IspD PF01128.19 KZN85129.1 - 0.0032 17.2 0.0 0.0058 16.4 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase APH PF01636.23 KZN85130.1 - 0.0092 15.9 0.4 0.022 14.7 0.1 1.9 3 0 0 3 3 3 1 Phosphotransferase enzyme family Dynamin_N PF00350.23 KZN85133.1 - 2.4e-24 86.3 0.0 1e-23 84.2 0.0 2.1 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KZN85133.1 - 4.5e-21 75.3 0.5 8.9e-17 61.2 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region GED PF02212.18 KZN85133.1 - 0.00048 20.2 0.0 0.0014 18.7 0.0 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KZN85133.1 - 0.00075 19.6 0.0 0.011 15.9 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arc_C PF18162.1 KZN85133.1 - 0.01 15.6 0.3 0.031 14.1 0.1 1.9 2 0 0 2 2 2 0 Arc C-lobe Roc PF08477.13 KZN85133.1 - 0.012 15.8 0.1 0.23 11.7 0.0 3.0 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase CDH1_2_SANT_HL1 PF18375.1 KZN85133.1 - 0.071 13.8 0.4 9 7.1 0.2 3.2 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 IIGP PF05049.13 KZN85133.1 - 0.075 12.1 0.0 11 4.9 0.0 2.5 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.6 KZN85133.1 - 0.14 12.5 0.9 0.88 9.9 0.0 2.7 4 1 0 4 4 4 0 AAA ATPase domain AAA_15 PF13175.6 KZN85133.1 - 0.24 11.1 0.9 1.9 8.1 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain tRNA-synt_2 PF00152.20 KZN85134.1 - 8.7e-77 258.3 0.9 1.2e-76 257.8 0.9 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KZN85134.1 - 2.6e-13 49.8 0.0 6.7e-13 48.4 0.1 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KZN85134.1 - 1e-05 25.2 0.1 0.014 14.9 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF3512 PF12024.8 KZN85134.1 - 0.053 13.0 0.4 0.1 12.1 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) Peptidase_S49_N PF08496.10 KZN85134.1 - 6.7 6.8 6.2 14 5.7 6.2 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal zf-C3HC4_2 PF13923.6 KZN85135.1 - 0.25 11.2 5.3 0.26 11.2 3.4 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 KZN85135.1 - 0.28 11.4 4.5 0.5 10.6 4.5 1.3 1 0 0 1 1 1 0 B-box zinc finger zf-C3HC4_3 PF13920.6 KZN85135.1 - 0.77 9.7 8.0 0.43 10.5 6.0 1.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) COX15-CtaA PF02628.15 KZN85136.1 - 1.7e-115 385.6 5.2 2e-115 385.3 5.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein zf-C3HC PF07967.13 KZN85137.1 - 1.7e-39 134.9 0.1 4.9e-36 123.7 0.0 2.4 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 KZN85137.1 - 7.6e-34 115.8 1.6 3.4e-31 107.2 0.0 3.3 3 0 0 3 3 3 2 Rsm1-like Pox_MCEL PF03291.16 KZN85138.1 - 1.5e-66 224.8 0.0 1.6e-42 145.9 0.0 3.3 2 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 KZN85138.1 - 1.2e-08 35.6 0.0 0.0058 17.3 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KZN85138.1 - 1.5e-07 32.0 0.0 9.5e-07 29.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN85138.1 - 2.3e-06 28.2 0.0 0.015 16.0 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KZN85138.1 - 8.5e-05 22.4 0.0 0.0026 17.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN85138.1 - 9e-05 22.4 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KZN85138.1 - 0.013 14.7 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family zf-Nse PF11789.8 KZN85139.1 - 7.4e-23 80.1 1.2 1.4e-22 79.2 1.2 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KZN85139.1 - 0.00051 20.0 0.2 0.0038 17.2 0.0 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-MIZ PF02891.20 KZN85139.1 - 0.011 15.5 2.8 0.067 12.9 2.8 2.0 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C3HC4_2 PF13923.6 KZN85139.1 - 0.017 14.9 0.6 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 KZN85139.1 - 0.15 12.3 0.2 0.45 10.7 0.2 1.8 1 1 0 1 1 1 0 U-box domain zf-RING_2 PF13639.6 KZN85139.1 - 0.23 11.8 0.9 0.52 10.7 0.9 1.6 1 1 0 1 1 1 0 Ring finger domain MFS_1 PF07690.16 KZN85140.1 - 5.8e-11 41.9 29.0 1.1e-10 41.0 28.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KZN85140.1 - 4.9e-09 36.1 6.2 4.9e-09 36.1 6.2 3.0 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 Mito_carr PF00153.27 KZN85141.1 - 1.4e-54 182.0 3.4 6.7e-18 64.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PEPCK_ATP PF01293.20 KZN85143.1 - 4.4e-214 711.4 0.0 5.3e-214 711.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 KZN85143.1 - 0.16 12.1 0.1 0.32 11.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain DZR PF12773.7 KZN85147.1 - 0.0066 16.5 4.8 0.0069 16.4 4.8 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf_C2H2_10 PF18414.1 KZN85147.1 - 0.29 10.7 0.4 0.29 10.7 0.4 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger zinc_ribbon_2 PF13240.6 KZN85147.1 - 0.32 10.8 0.7 0.32 10.8 0.7 2.4 1 1 1 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KZN85147.1 - 0.48 9.9 11.6 0.096 12.1 7.6 1.9 1 1 0 1 1 1 0 zinc-ribbon domain zf-tcix PF14952.6 KZN85147.1 - 0.88 9.2 12.8 0.17 11.6 5.1 2.1 1 1 1 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding zf-RRN7 PF11781.8 KZN85147.1 - 1.1 9.0 8.1 1.7 8.4 1.3 2.3 1 1 1 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Zn-ribbon_8 PF09723.10 KZN85147.1 - 8.1 6.7 10.3 0.92 9.7 1.2 2.2 1 1 1 2 2 2 0 Zinc ribbon domain PEX11 PF05648.14 KZN85148.1 - 1.6e-76 256.7 0.1 1.8e-76 256.5 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) COX14 PF14880.6 KZN85148.1 - 0.042 13.7 0.3 0.34 10.8 0.0 2.6 2 0 0 2 2 2 0 Cytochrome oxidase c assembly TBPIP PF07106.13 KZN85148.1 - 0.051 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain Arch_fla_DE PF04659.13 KZN85148.1 - 0.11 12.4 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Archaeal flagella protein Sugar_tr PF00083.24 KZN85149.1 - 2.2e-28 99.3 31.7 7.8e-19 67.9 11.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KZN85149.1 - 5.5e-16 58.4 41.4 1.8e-11 43.6 19.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PDR_CDR PF06422.12 KZN85149.1 - 7.9 6.5 6.1 8.8 6.3 0.1 3.2 3 0 0 3 3 3 0 CDR ABC transporter RPN7 PF10602.9 KZN85150.1 - 3e-53 180.1 0.2 4.7e-53 179.5 0.2 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KZN85150.1 - 5.4e-15 55.8 0.0 1.2e-14 54.7 0.0 1.6 1 0 0 1 1 1 1 PCI domain Aminotran_1_2 PF00155.21 KZN85151.1 - 3.3e-39 135.1 0.0 5.6e-39 134.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Exo_endo_phos PF03372.23 KZN85152.1 - 1.7e-06 27.8 0.0 3.4e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Abhydrolase_6 PF12697.7 KZN85153.1 - 6.2e-14 53.1 7.2 1.1e-13 52.3 7.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KZN85153.1 - 4.3e-13 49.5 0.5 6.4e-13 48.9 0.5 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KZN85153.1 - 8.6e-07 28.5 0.1 1.3e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KZN85153.1 - 0.00021 21.5 0.0 0.00031 20.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 KZN85153.1 - 0.076 12.7 0.0 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Copper-fist PF00649.18 KZN85154.1 - 3.6e-21 74.4 3.7 3.6e-21 74.4 3.7 2.2 2 1 1 3 3 3 1 Copper fist DNA binding domain Zn_clus PF00172.18 KZN85155.1 - 2.9e-10 40.1 8.2 4.6e-10 39.4 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IL34 PF15036.6 KZN85155.1 - 0.14 12.2 0.0 3.1 7.8 0.0 2.2 2 0 0 2 2 2 0 Interleukin 34 zf_ZIC PF18366.1 KZN85157.1 - 0.0011 19.0 0.0 0.0027 17.8 0.0 1.7 1 0 0 1 1 1 1 Zic proteins zinc finger domain RFX_DNA_binding PF02257.15 KZN85157.1 - 0.011 16.4 0.0 0.02 15.5 0.0 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain SspK PF08176.12 KZN85157.1 - 0.018 15.3 0.0 0.071 13.4 0.0 2.1 2 0 0 2 2 2 0 Small acid-soluble spore protein K family RPE65 PF03055.15 KZN85158.1 - 5e-112 375.4 0.0 5.7e-112 375.3 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Fungal_trans PF04082.18 KZN85159.1 - 5.7e-16 58.3 0.1 9e-16 57.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN85159.1 - 6.4e-08 32.6 6.6 6.4e-08 32.6 6.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PrgI PF12666.7 KZN85161.1 - 5.8 7.7 9.3 0.92 10.3 0.2 3.1 3 0 0 3 3 3 0 PrgI family protein ArfGap PF01412.18 KZN85162.1 - 8e-40 135.6 0.2 1.2e-39 135.0 0.2 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SelR PF01641.18 KZN85163.1 - 1.3e-49 167.3 0.1 1.7e-49 166.9 0.1 1.1 1 0 0 1 1 1 1 SelR domain Auxin_repressed PF05564.12 KZN85163.1 - 0.0036 18.0 0.3 0.0055 17.4 0.3 1.3 1 0 0 1 1 1 1 Dormancy/auxin associated protein zinc_ribbon_10 PF10058.9 KZN85163.1 - 0.056 13.2 0.3 0.46 10.2 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DZR PF12773.7 KZN85163.1 - 0.068 13.2 0.3 10 6.2 0.0 2.4 2 0 0 2 2 2 0 Double zinc ribbon MCM_OB PF17207.3 KZN85163.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 MCM OB domain CUE PF02845.16 KZN85164.1 - 0.016 14.9 0.7 0.031 14.0 0.1 1.8 2 0 0 2 2 2 0 CUE domain Smr PF01713.21 KZN85164.1 - 0.04 14.3 0.2 0.1 13.0 0.2 1.7 1 0 0 1 1 1 0 Smr domain Zds_C PF08632.10 KZN85165.1 - 7.8e-28 96.0 1.3 1.5e-27 95.1 1.3 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Ysc84 PF04366.12 KZN85166.1 - 1.4e-39 134.8 0.7 2.8e-39 133.8 0.7 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 KZN85166.1 - 9.1e-13 47.6 0.2 3.2e-12 45.8 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KZN85166.1 - 3.1e-11 42.8 0.1 8e-11 41.5 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KZN85166.1 - 1e-09 38.1 0.0 2.2e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain EF_assoc_2 PF08356.12 KZN85167.1 - 5.8e-35 119.2 0.0 1.1e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 KZN85167.1 - 4.7e-31 106.2 0.1 8e-31 105.5 0.1 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 KZN85167.1 - 1.9e-24 86.1 0.0 1.9e-14 53.6 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KZN85167.1 - 1.3e-11 44.8 0.0 6.9e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KZN85167.1 - 4.5e-10 39.6 0.0 0.00013 22.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.32 KZN85167.1 - 9.8e-08 31.0 1.0 0.0024 17.3 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KZN85167.1 - 1e-06 28.2 0.7 0.0036 17.1 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KZN85167.1 - 1.4e-05 25.5 0.1 0.0067 16.9 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair AAA_29 PF13555.6 KZN85167.1 - 2.2e-05 24.1 0.2 0.017 14.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KZN85167.1 - 0.00011 22.7 1.6 0.13 12.6 0.1 2.9 3 1 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 KZN85167.1 - 0.00022 21.5 0.5 1.6 9.0 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KZN85167.1 - 0.00032 21.3 0.1 1.5 9.4 0.2 2.8 2 1 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 KZN85167.1 - 0.00037 20.6 0.5 0.65 10.0 0.2 2.8 2 1 0 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 KZN85167.1 - 0.00039 20.0 0.1 3 7.3 0.0 3.2 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain AAA_28 PF13521.6 KZN85167.1 - 0.00069 19.9 0.1 0.35 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KZN85167.1 - 0.0013 18.7 0.2 1.9 8.3 0.1 3.4 3 0 0 3 3 3 1 RsgA GTPase EF-hand_8 PF13833.6 KZN85167.1 - 0.0014 18.4 0.4 0.49 10.3 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair Viral_helicase1 PF01443.18 KZN85167.1 - 0.0019 18.0 0.2 0.044 13.5 0.0 2.6 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase EF-hand_5 PF13202.6 KZN85167.1 - 0.0021 17.5 2.1 0.13 11.8 0.2 2.7 2 0 0 2 2 2 1 EF hand RNA_helicase PF00910.22 KZN85167.1 - 0.0053 17.1 0.0 1 9.8 0.0 2.5 2 0 0 2 2 2 1 RNA helicase ABC_tran PF00005.27 KZN85167.1 - 0.0068 16.9 0.0 5.7 7.4 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_25 PF13481.6 KZN85167.1 - 0.0078 15.8 0.2 3.3 7.2 0.0 2.8 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 KZN85167.1 - 0.009 15.9 0.5 4.4 7.2 0.0 2.7 2 1 0 2 2 2 1 NACHT domain FtsK_SpoIIIE PF01580.18 KZN85167.1 - 0.0094 15.3 0.1 0.85 8.9 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_24 PF13479.6 KZN85167.1 - 0.021 14.5 0.1 0.3 10.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KZN85167.1 - 0.023 14.6 0.0 2.5 8.0 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 KZN85167.1 - 0.025 14.7 0.1 7 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KZN85167.1 - 0.03 13.8 0.1 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 KZN85167.1 - 0.041 13.9 0.6 29 4.6 0.0 3.2 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) Septin PF00735.18 KZN85167.1 - 0.054 12.8 0.0 0.82 8.9 0.0 2.2 2 0 0 2 2 2 0 Septin DUF815 PF05673.13 KZN85167.1 - 0.055 12.6 0.2 2.1 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) EF-hand_10 PF14788.6 KZN85167.1 - 0.086 12.7 0.8 0.65 9.9 0.1 2.3 2 0 0 2 2 2 0 EF hand SMC_N PF02463.19 KZN85167.1 - 0.093 12.1 0.3 2.6 7.4 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain IIGP PF05049.13 KZN85167.1 - 0.1 11.7 0.4 1.7 7.6 0.1 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA PF00004.29 KZN85167.1 - 0.11 13.0 0.5 16 5.9 0.0 3.2 3 1 1 4 4 3 0 ATPase family associated with various cellular activities (AAA) SPARC_Ca_bdg PF10591.9 KZN85167.1 - 0.11 12.8 0.5 3.6 7.9 0.1 2.9 2 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3201 PF11447.8 KZN85167.1 - 0.12 12.0 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3201) MCM PF00493.23 KZN85167.1 - 0.12 11.5 0.0 3.4 6.7 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain cobW PF02492.19 KZN85167.1 - 0.32 10.6 1.7 8.3 6.0 0.1 3.5 4 1 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 KZN85167.1 - 0.34 10.7 1.8 47 3.7 0.0 3.4 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein ANAPC4_WD40 PF12894.7 KZN85168.1 - 3.9e-11 43.1 0.0 0.003 17.8 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KZN85168.1 - 7.6e-09 36.1 14.3 0.00056 20.7 0.3 5.5 5 1 0 5 5 5 3 WD domain, G-beta repeat IKI3 PF04762.12 KZN85168.1 - 7e-05 21.0 0.0 0.0014 16.7 0.0 2.0 1 1 1 2 2 2 2 IKI3 family eIF2A PF08662.11 KZN85168.1 - 0.013 15.4 0.1 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KZN85168.1 - 0.014 13.9 0.0 0.037 12.5 0.0 1.6 2 0 0 2 2 2 0 Cytochrome D1 heme domain Utp8 PF10395.9 KZN85168.1 - 0.2 10.1 0.0 0.27 9.7 0.0 1.2 1 0 0 1 1 1 0 Utp8 family Pkinase PF00069.25 KZN85169.1 - 1.5e-23 83.5 0.0 2.2e-22 79.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN85169.1 - 1.8e-11 43.9 0.0 7.3e-07 28.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase GPI-anchored PF10342.9 KZN85170.1 - 1.9e-18 67.0 0.8 1.9e-18 67.0 0.8 4.6 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family AAA_22 PF13401.6 KZN85171.1 - 0.00051 20.3 0.1 0.3 11.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KZN85171.1 - 0.007 16.8 0.1 0.032 14.7 0.1 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 KZN85171.1 - 0.016 14.6 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 KZN85171.1 - 0.073 12.3 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 KZN85171.1 - 0.11 12.8 0.1 3.4 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Adeno_IVa2 PF02456.15 KZN85171.1 - 0.14 11.0 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Ank_4 PF13637.6 KZN85172.1 - 2.1e-15 56.8 0.1 8e-07 29.5 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KZN85172.1 - 6.1e-14 52.4 0.2 7.3e-07 29.7 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KZN85172.1 - 5e-12 45.8 0.3 0.00095 19.4 0.0 5.8 4 1 2 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN85172.1 - 2.7e-10 39.6 0.3 0.05 14.2 0.0 6.0 7 0 0 7 7 7 2 Ankyrin repeat Ank PF00023.30 KZN85172.1 - 0.0002 21.7 3.0 2.8 8.5 0.1 4.9 4 1 0 4 4 4 2 Ankyrin repeat F-box-like PF12937.7 KZN85172.1 - 0.043 13.7 0.2 0.09 12.7 0.2 1.5 1 0 0 1 1 1 0 F-box-like Ribonuc_L-PSP PF01042.21 KZN85173.1 - 1e-09 38.4 0.2 8e-08 32.3 0.1 2.3 2 1 0 2 2 2 1 Endoribonuclease L-PSP Zn_clus PF00172.18 KZN85174.1 - 2.7e-08 33.8 14.7 5.4e-08 32.8 14.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.13 KZN85175.1 - 3.8e-37 127.9 6.7 5.6e-37 127.4 6.7 1.2 1 0 0 1 1 1 1 RTA1 like protein DAO PF01266.24 KZN85176.1 - 2.5e-41 142.4 0.0 2.9e-41 142.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KZN85176.1 - 8.4e-06 25.9 0.0 2.1e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KZN85176.1 - 8.7e-05 21.9 0.0 0.043 13.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KZN85176.1 - 0.00014 21.1 0.0 0.039 13.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.6 KZN85176.1 - 0.0014 18.7 0.3 0.94 9.4 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding GIDA PF01134.22 KZN85176.1 - 0.0019 17.4 0.4 0.049 12.7 0.1 2.3 2 1 0 2 2 2 1 Glucose inhibited division protein A Glu_dehyd_C PF16912.5 KZN85176.1 - 0.0071 15.9 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus FAD_binding_3 PF01494.19 KZN85176.1 - 0.0089 15.3 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KZN85176.1 - 0.015 14.6 0.0 0.049 12.9 0.0 1.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KZN85176.1 - 0.015 15.8 0.0 0.037 14.6 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KZN85176.1 - 0.049 13.9 0.0 0.094 13.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 KZN85176.1 - 0.052 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Zn_clus PF00172.18 KZN85177.1 - 1.8e-09 37.6 8.9 3.4e-09 36.7 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Synaptobrevin PF00957.21 KZN85178.1 - 0.16 11.8 1.0 0.34 10.7 0.2 1.7 1 1 1 2 2 2 0 Synaptobrevin Arrestin_C PF02752.22 KZN85179.1 - 7.2e-20 71.8 0.1 1.3e-19 70.9 0.1 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KZN85179.1 - 2.6e-10 40.5 0.0 4.1e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KZN85179.1 - 0.0071 16.1 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like TolA_bind_tri PF16331.5 KZN85180.1 - 0.53 10.4 7.0 0.32 11.1 4.5 2.0 2 0 0 2 2 2 0 TolA binding protein trimerisation Nup54 PF13874.6 KZN85180.1 - 1.5 8.9 8.3 8.3 6.5 2.8 3.0 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 Glyoxalase PF00903.25 KZN85182.1 - 6.7e-42 142.7 0.1 8.8e-20 71.2 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KZN85182.1 - 3.5e-14 53.0 0.0 3e-05 24.2 0.0 3.9 1 1 1 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KZN85182.1 - 6.6e-07 29.6 0.0 0.027 14.6 0.0 3.3 2 1 1 3 3 3 2 Glyoxalase-like domain Glyoxalase_6 PF18029.1 KZN85182.1 - 8.2e-06 26.6 0.0 0.18 12.6 0.0 2.9 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KZN85182.1 - 0.00099 19.0 0.3 5.9 6.9 0.0 3.8 4 1 0 4 4 4 2 Glyoxalase-like domain DUF1338 PF07063.13 KZN85182.1 - 0.071 12.3 0.0 18 4.4 0.0 3.2 3 1 0 4 4 4 0 Domain of unknown function (DUF1338) CppA_N PF14506.6 KZN85182.1 - 0.11 12.6 0.3 0.6 10.2 0.0 2.1 2 0 0 2 2 2 0 CppA N-terminal Fungal_trans PF04082.18 KZN85183.1 - 1.2e-17 63.9 0.0 1.9e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN85183.1 - 9.4e-10 38.5 13.2 1.6e-09 37.8 13.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.13 KZN85184.1 - 1.8e-06 28.0 0.0 0.0001 22.2 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KZN85184.1 - 0.00077 19.2 0.0 0.0014 18.3 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KZN85184.1 - 0.059 12.2 0.0 0.085 11.7 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase Esterase PF00756.20 KZN85184.1 - 0.082 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 KZN85184.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.28 KZN85184.1 - 0.19 10.6 0.0 0.37 9.6 0.0 1.4 1 0 0 1 1 1 0 Carboxylesterase family Peptidase_C2 PF00648.21 KZN85185.1 - 6.7e-63 212.5 0.4 4.7e-41 140.7 0.1 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease Pkinase PF00069.25 KZN85186.1 - 9.5e-70 235.0 0.0 1.3e-69 234.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN85186.1 - 1.4e-30 106.4 0.0 1.8e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KZN85186.1 - 0.00019 20.5 0.0 0.012 14.6 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain Kinase-like PF14531.6 KZN85186.1 - 0.00022 20.6 0.0 0.00043 19.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KZN85186.1 - 0.0037 17.2 0.0 0.0092 15.9 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KZN85186.1 - 0.0086 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 KZN85186.1 - 0.12 11.8 0.0 0.26 10.6 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family 2OG-FeII_Oxy_2 PF13532.6 KZN85187.1 - 2.5e-27 96.3 0.0 6e-27 95.1 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidase PF01425.21 KZN85188.1 - 3.9e-102 342.5 0.0 6e-102 341.9 0.0 1.3 1 1 0 1 1 1 1 Amidase zf-C2H2_4 PF13894.6 KZN85189.1 - 0.17 12.8 0.4 0.46 11.5 0.4 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger ABC2_membrane PF01061.24 KZN85190.1 - 2e-82 275.7 53.3 4.4e-48 163.5 22.2 2.8 4 0 0 4 4 2 2 ABC-2 type transporter ABC_tran PF00005.27 KZN85190.1 - 9.2e-37 126.6 0.0 1.7e-17 64.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KZN85190.1 - 5.3e-34 116.0 1.0 2.6e-26 91.4 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KZN85190.1 - 1e-11 45.3 0.2 4e-11 43.4 0.2 2.1 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KZN85190.1 - 9.7e-11 41.4 35.4 1.2e-06 27.9 17.2 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 KZN85190.1 - 5.1e-07 30.2 0.1 3.2e-05 24.4 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KZN85190.1 - 6.6e-07 29.4 0.2 0.025 14.4 0.0 2.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KZN85190.1 - 2.4e-06 28.1 0.0 0.0049 17.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KZN85190.1 - 2.6e-05 23.9 0.1 0.0072 16.0 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KZN85190.1 - 6.6e-05 22.9 0.4 0.00027 20.9 0.1 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KZN85190.1 - 6.7e-05 22.6 0.0 0.0035 17.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KZN85190.1 - 0.00014 22.2 0.4 0.088 13.1 0.2 3.2 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KZN85190.1 - 0.0011 18.7 0.1 0.058 13.1 0.1 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KZN85190.1 - 0.0028 17.6 0.1 0.034 14.1 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.6 KZN85190.1 - 0.0047 17.2 0.2 0.0047 17.2 0.2 2.2 3 0 0 3 3 1 1 AAA domain AAA_33 PF13671.6 KZN85190.1 - 0.0068 16.6 0.0 0.22 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KZN85190.1 - 0.011 16.2 0.2 0.089 13.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KZN85190.1 - 0.012 16.1 0.1 0.049 14.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KZN85190.1 - 0.014 14.7 0.9 2 7.7 0.1 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_ATPase PF09818.9 KZN85190.1 - 0.016 14.1 0.2 1.7 7.4 0.1 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class MMR_HSR1 PF01926.23 KZN85190.1 - 0.017 15.2 1.1 0.61 10.2 0.3 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.19 KZN85190.1 - 0.018 14.5 0.1 6.2 6.2 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain GET2 PF08690.10 KZN85190.1 - 0.049 13.3 4.2 1.5 8.4 1.7 2.5 2 0 0 2 2 2 0 GET complex subunit GET2 cobW PF02492.19 KZN85190.1 - 0.05 13.2 0.2 0.25 10.9 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 KZN85190.1 - 0.052 13.9 0.1 3.8 7.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase dNK PF01712.19 KZN85190.1 - 0.066 13.1 0.0 0.41 10.5 0.0 2.0 2 0 0 2 2 2 0 Deoxynucleoside kinase T2SSE PF00437.20 KZN85190.1 - 0.089 11.8 0.2 0.28 10.2 0.1 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA PF00004.29 KZN85190.1 - 0.098 13.1 0.0 1.2 9.6 0.0 2.7 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) DJ-1_PfpI PF01965.24 KZN85193.1 - 1.3e-12 47.8 0.0 5.9e-12 45.7 0.0 2.1 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KZN85193.1 - 4e-12 46.2 0.0 5.4e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like Glyco_transf_4 PF13439.6 KZN85193.1 - 0.08 12.9 0.0 0.29 11.1 0.0 1.8 1 1 0 1 1 1 0 Glycosyltransferase Family 4 GMC_oxred_N PF00732.19 KZN85194.1 - 3.4e-75 253.2 0.0 4.8e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KZN85194.1 - 2.5e-34 118.8 0.1 1.7e-33 116.1 0.1 2.1 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KZN85194.1 - 9.2e-06 25.0 0.0 0.0041 16.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KZN85194.1 - 0.001 18.2 0.1 0.0016 17.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KZN85194.1 - 0.0091 15.6 1.1 0.094 12.3 0.8 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KZN85194.1 - 0.026 13.8 0.2 0.21 10.8 0.1 2.0 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.14 KZN85194.1 - 0.11 11.7 0.0 0.33 10.1 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AAA_22 PF13401.6 KZN85195.1 - 0.0004 20.7 0.0 0.0012 19.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KZN85195.1 - 0.001 19.0 0.0 0.0023 17.9 0.0 1.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea ATPase PF06745.13 KZN85195.1 - 0.0011 18.4 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_16 PF13191.6 KZN85195.1 - 0.0017 18.8 0.0 0.0037 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KZN85195.1 - 0.0019 18.2 0.0 0.0055 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.18 KZN85195.1 - 0.03 14.2 1.0 0.11 12.3 0.0 2.3 3 0 0 3 3 3 0 Bacterial dnaA protein KAP_NTPase PF07693.14 KZN85195.1 - 0.032 13.5 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_7 PF12775.7 KZN85195.1 - 0.04 13.4 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 KZN85195.1 - 0.08 13.2 0.1 0.42 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KZN85195.1 - 0.09 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KZN85195.1 - 0.091 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AMP-binding PF00501.28 KZN85197.1 - 5.7e-60 203.1 0.0 8.3e-60 202.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.24 KZN85197.1 - 2.8e-12 45.8 8.9 2.5e-05 23.8 0.1 7.1 7 0 0 7 7 7 3 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.25 KZN85197.1 - 1.5e-11 44.5 0.0 3.7e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep_2 PF14602.6 KZN85197.1 - 2.2e-05 24.1 13.9 1.6 8.6 0.4 6.3 7 0 0 7 7 7 3 Hexapeptide repeat of succinyl-transferase DUF1993 PF09351.10 KZN85199.1 - 6.9e-55 185.6 0.4 7.7e-55 185.4 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DUF3196 PF11428.8 KZN85199.1 - 0.056 13.0 0.5 0.073 12.6 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3196) DUF3867 PF12983.7 KZN85199.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3867) DraK_HK_N PF18092.1 KZN85199.1 - 0.13 12.7 0.1 0.29 11.6 0.0 1.6 2 0 0 2 2 2 0 DraK Histidine Kinase N-terminal domain IF-2B PF01008.17 KZN85199.1 - 0.17 11.0 1.0 0.24 10.6 1.0 1.2 1 0 0 1 1 1 0 Initiation factor 2 subunit family Pec_lyase_C PF00544.19 KZN85201.1 - 6.3e-16 58.6 10.5 1.3e-14 54.3 10.5 2.1 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KZN85201.1 - 0.0017 18.2 14.8 0.0033 17.3 11.3 2.5 1 1 1 2 2 2 2 Right handed beta helix region DUF222 PF02720.17 KZN85202.1 - 0.079 12.4 0.4 0.11 12.0 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF222) DUF3716 PF12511.8 KZN85203.1 - 7.2e-08 32.4 2.8 1.2e-07 31.6 2.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Fungal_trans_2 PF11951.8 KZN85205.1 - 1e-09 37.7 0.2 2.4e-08 33.2 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN85205.1 - 1.7e-06 28.1 15.4 3.1e-06 27.2 15.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box PF00646.33 KZN85207.1 - 0.014 15.3 0.0 0.036 14.0 0.0 1.7 1 0 0 1 1 1 0 F-box domain Ank_2 PF12796.7 KZN85208.1 - 1.3e-113 371.7 28.6 1.7e-12 47.7 0.0 14.2 7 3 7 15 15 15 15 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN85208.1 - 6.7e-90 294.4 30.3 2.1e-10 40.9 0.3 18.3 10 6 6 18 18 18 15 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN85208.1 - 3.2e-73 232.9 42.9 0.00027 21.1 0.0 26.4 29 0 0 29 29 28 15 Ankyrin repeat Ank_5 PF13857.6 KZN85208.1 - 1.4e-69 229.2 37.6 2.5e-08 34.0 0.0 19.5 13 5 8 21 21 20 15 Ankyrin repeats (many copies) Ank PF00023.30 KZN85208.1 - 4.5e-56 185.0 69.3 2e-05 24.8 0.1 23.9 24 0 0 24 24 24 14 Ankyrin repeat NACHT PF05729.12 KZN85208.1 - 4.8e-08 33.1 0.1 4.2e-07 30.0 0.0 2.6 3 0 0 3 3 3 1 NACHT domain AAA_16 PF13191.6 KZN85208.1 - 1.1e-05 25.9 0.8 0.0009 19.7 0.0 3.7 4 0 0 4 4 4 1 AAA ATPase domain NACHT_N PF17100.5 KZN85208.1 - 1.3e-05 25.2 0.4 7.4e-05 22.7 0.4 2.0 1 1 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase AAA_33 PF13671.6 KZN85208.1 - 0.072 13.2 0.0 0.44 10.7 0.0 2.5 1 0 0 1 1 1 0 AAA domain VWA_3_C PF18571.1 KZN85208.1 - 0.086 12.7 6.7 1.6 8.7 0.2 4.6 5 0 0 5 5 5 0 von Willebrand factor type A C-terminal domain Lipoprotein_20 PF13942.6 KZN85208.1 - 0.33 10.8 2.3 0.41 10.5 0.1 2.1 2 0 0 2 2 2 0 YfhG lipoprotein Pkinase PF00069.25 KZN85210.1 - 6.2e-19 68.4 0.0 7.7e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN85210.1 - 5.8e-06 25.8 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase WGG PF10273.9 KZN85211.1 - 8.2e-30 103.3 0.7 1.5e-29 102.4 0.7 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 zf-ZPR1 PF03367.13 KZN85211.1 - 0.14 12.1 0.3 0.2 11.5 0.3 1.3 1 0 0 1 1 1 0 ZPR1 zinc-finger domain Ribosomal_60s PF00428.19 KZN85211.1 - 6.4 7.4 9.1 0.45 11.1 4.1 1.7 2 1 0 2 2 2 0 60s Acidic ribosomal protein GTP_EFTU PF00009.27 KZN85212.1 - 8.4e-38 129.9 0.0 1.3e-37 129.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KZN85212.1 - 5.2e-28 97.6 0.0 1e-27 96.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KZN85212.1 - 2.2e-05 24.8 0.0 5.8e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KZN85212.1 - 0.0083 16.2 0.0 0.027 14.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF5035 PF16438.5 KZN85212.1 - 0.087 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5035) Hamartin PF04388.12 KZN85212.1 - 0.15 10.7 2.7 0.2 10.3 2.7 1.1 1 0 0 1 1 1 0 Hamartin protein Ran-binding PF05508.11 KZN85213.1 - 2.1e-108 362.0 0.2 2.6e-108 361.7 0.2 1.1 1 0 0 1 1 1 1 RanGTP-binding protein BSD PF03909.17 KZN85214.1 - 3e-20 71.9 0.6 6.2e-20 71.0 0.6 1.6 1 0 0 1 1 1 1 BSD domain GFO_IDH_MocA PF01408.22 KZN85215.1 - 1.5e-19 71.0 0.0 2.6e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 KZN85215.1 - 2.7e-05 24.6 0.0 4.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Rad4 PF03835.15 KZN85216.1 - 4.5e-36 123.7 0.1 1.2e-35 122.4 0.1 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KZN85216.1 - 3.9e-29 100.9 0.0 8.4e-29 99.8 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KZN85216.1 - 9.4e-21 73.4 0.1 1.9e-20 72.4 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KZN85216.1 - 6.5e-18 65.5 0.1 6.5e-18 65.5 0.1 3.9 4 1 0 4 4 4 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KZN85216.1 - 0.019 15.4 0.0 0.075 13.5 0.0 2.1 1 1 0 1 1 1 0 Transglutaminase-like superfamily Cep57_MT_bd PF06657.13 KZN85216.1 - 0.11 13.0 0.1 0.46 11.0 0.1 2.1 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Methyltransf_23 PF13489.6 KZN85217.1 - 7.3e-22 77.9 0.0 1.1e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN85217.1 - 5.2e-09 36.7 0.0 1.6e-08 35.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN85217.1 - 1.7e-06 28.7 0.0 7.2e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN85217.1 - 2.8e-06 27.2 0.0 3.1e-05 23.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN85217.1 - 4.8e-06 27.1 0.0 9.9e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KZN85217.1 - 0.001 18.5 0.0 0.0051 16.2 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KZN85217.1 - 0.0018 17.7 0.0 0.0073 15.7 0.0 1.8 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KZN85217.1 - 0.0062 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 KZN85217.1 - 0.007 15.8 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_16 PF10294.9 KZN85217.1 - 0.015 15.0 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase PCMT PF01135.19 KZN85217.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Proteasome PF00227.26 KZN85219.1 - 6.9e-45 152.9 0.1 9.1e-45 152.5 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KZN85219.1 - 2e-12 46.3 0.2 2e-12 46.3 0.2 1.9 2 0 0 2 2 2 1 Proteasome beta subunits C terminal ANAPC4_WD40 PF12894.7 KZN85220.1 - 0.14 12.5 0.0 0.4 11.0 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain KH_1 PF00013.29 KZN85223.1 - 1.2e-44 150.0 2.9 2.2e-17 62.6 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KZN85223.1 - 1.5e-12 47.1 2.2 0.0045 16.8 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KZN85223.1 - 1.6e-06 27.9 0.2 0.67 9.9 0.1 3.3 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 KZN85223.1 - 9.4e-05 22.3 0.0 0.019 14.9 0.0 2.5 2 0 0 2 2 2 2 KH-like RNA-binding domain KH_5 PF13184.6 KZN85223.1 - 9.5e-05 22.4 7.0 0.31 11.1 0.2 3.3 3 0 0 3 3 3 2 NusA-like KH domain AceK PF06315.11 KZN85224.1 - 0.017 13.6 5.3 0.026 13.0 5.3 1.2 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) CENP-K PF11802.8 KZN85224.1 - 0.94 9.0 16.4 1.6 8.2 0.0 3.1 2 1 1 3 3 3 0 Centromere-associated protein K Draxin PF15550.6 KZN85224.1 - 5.6 6.7 10.7 0.6 9.9 5.4 1.9 2 0 0 2 2 2 0 Draxin ArAE_2_N PF10337.9 KZN85224.1 - 9.4 5.1 7.5 0.54 9.2 1.5 1.8 2 0 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal Fzo_mitofusin PF04799.13 KZN85224.1 - 9.6 5.7 9.8 0.79 9.2 0.3 2.8 2 1 1 3 3 3 0 fzo-like conserved region DEAD PF00270.29 KZN85225.1 - 2.1e-21 76.5 0.0 1.5e-20 73.7 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KZN85225.1 - 4e-18 65.8 0.0 7e-15 55.3 0.0 3.4 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KZN85225.1 - 3e-16 59.9 7.6 9.1e-16 58.3 7.6 1.9 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 KZN85225.1 - 9.5e-16 57.6 0.0 2e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 RQC domain HRDC PF00570.23 KZN85225.1 - 1.6e-07 31.2 0.0 6.4e-07 29.3 0.0 2.1 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.15 KZN85225.1 - 3.5e-05 23.9 0.0 0.0001 22.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4110 PF13422.6 KZN85226.1 - 3.2e-32 110.5 1.5 3.2e-32 110.5 1.5 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.6 KZN85226.1 - 7.8e-26 89.8 14.6 6e-07 29.4 0.0 6.3 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KZN85226.1 - 8.5e-25 86.5 13.7 1.2e-08 35.0 0.1 6.5 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KZN85226.1 - 2.5e-15 56.0 5.1 8.2e-06 25.7 0.1 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 KZN85226.1 - 1e-13 51.0 7.2 0.0013 18.9 0.3 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 KZN85226.1 - 1.7e-13 49.9 0.0 1.4e-05 24.6 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 KZN85226.1 - 9.5e-12 44.4 9.8 0.00036 20.4 0.0 6.0 6 1 0 6 6 6 4 Kelch motif Bd3614-deam PF14439.6 KZN85226.1 - 5.8 7.0 6.1 18 5.4 3.4 2.3 2 0 0 2 2 2 0 Bd3614-like deaminase Pyridoxal_deC PF00282.19 KZN85227.1 - 2.7e-26 92.2 0.0 4e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KZN85227.1 - 0.0086 15.4 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KZN85227.1 - 0.014 14.6 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II SepSecS PF05889.13 KZN85227.1 - 0.025 13.3 0.0 0.07 11.8 0.0 1.6 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Aminotran_5 PF00266.19 KZN85227.1 - 0.029 13.3 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V MFS_1 PF07690.16 KZN85228.1 - 1.1e-31 110.1 41.5 1.1e-31 110.1 41.5 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KZN85228.1 - 1.3e-16 60.2 21.3 1.6e-16 59.8 21.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KZN85228.1 - 3.6e-12 45.9 9.8 3.6e-12 45.9 9.8 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 KZN85228.1 - 0.00029 19.4 3.0 0.00029 19.4 3.0 2.9 3 0 0 3 3 3 1 Transmembrane secretion effector Abhydrolase_1 PF00561.20 KZN85229.1 - 2.6e-14 53.5 0.0 7.1e-14 52.1 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KZN85229.1 - 7.9e-08 31.9 0.0 1.9e-07 30.6 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KZN85229.1 - 0.0028 18.3 0.0 0.0053 17.4 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KZN85229.1 - 0.0066 15.9 0.0 0.037 13.5 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KZN85229.1 - 0.017 14.7 0.0 0.036 13.7 0.0 1.7 1 1 0 1 1 1 0 Putative esterase RNA_pol_inhib PF16857.5 KZN85229.1 - 0.047 13.5 1.9 4.8 7.1 0.5 2.6 2 0 0 2 2 2 0 RNA polymerase inhibitor Mon1 PF03164.14 KZN85230.1 - 9.4e-155 515.6 0.0 1.1e-154 515.4 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Dopey_N PF04118.14 KZN85231.1 - 1.7e-115 385.4 0.0 3.6e-115 384.3 0.0 1.6 1 0 0 1 1 1 1 Dopey, N-terminal Hpt PF01627.23 KZN85231.1 - 0.025 14.9 0.1 2.6 8.4 0.0 3.6 3 0 0 3 3 3 0 Hpt domain MazG PF03819.17 KZN85231.1 - 0.2 11.9 2.0 1 9.6 0.0 2.8 3 0 0 3 3 3 0 MazG nucleotide pyrophosphohydrolase domain MnhB PF04039.13 KZN85232.1 - 0.033 14.5 0.6 0.053 13.8 0.6 1.4 1 1 0 1 1 1 0 Domain related to MnhB subunit of Na+/H+ antiporter DUF4741 PF15897.5 KZN85233.1 - 0.019 14.8 0.3 0.059 13.2 0.1 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4741) MBOAT PF03062.19 KZN85234.1 - 3.4e-38 131.9 20.4 2.5e-32 112.6 4.3 2.5 3 0 0 3 3 3 2 MBOAT, membrane-bound O-acyltransferase family AOX PF01786.17 KZN85235.1 - 5.3e-100 333.4 0.0 6.7e-100 333.1 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase KAR9 PF08580.10 KZN85236.1 - 1.6e-228 760.7 1.1 1.6e-228 760.7 1.1 2.5 1 1 1 2 2 2 1 Yeast cortical protein KAR9 FAA_hydro_N_2 PF18288.1 KZN85236.1 - 0.077 13.4 0.2 0.33 11.4 0.2 2.1 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 DNA_photolyase PF00875.18 KZN85236.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 DNA photolyase NPV_P10 PF05531.12 KZN85236.1 - 0.35 11.4 5.7 0.34 11.4 0.5 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Prominin PF05478.11 KZN85236.1 - 2.9 5.7 4.3 12 3.6 0.8 2.2 2 0 0 2 2 2 0 Prominin Acetyltransf_1 PF00583.25 KZN85237.1 - 4.5e-06 26.9 0.0 5.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KZN85237.1 - 9e-06 26.4 0.0 1.6e-05 25.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KZN85237.1 - 0.00038 20.8 0.0 0.00071 20.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KZN85237.1 - 0.018 15.0 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.7 KZN85237.1 - 0.039 14.1 0.0 0.058 13.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KZN85237.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Complex1_LYR_2 PF13233.6 KZN85238.1 - 5.4e-21 75.1 0.2 7.3e-21 74.7 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KZN85238.1 - 2.2e-10 40.4 0.0 3.2e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) MTS PF05175.14 KZN85239.1 - 0.0017 18.0 0.0 0.0039 16.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain LSM PF01423.22 KZN85240.1 - 6e-13 48.3 0.0 2.1e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 LSM domain zf-C2H2 PF00096.26 KZN85241.1 - 6.6e-05 23.1 0.9 0.27 11.8 0.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KZN85241.1 - 0.00083 20.0 0.4 1.1 10.3 0.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger GAGA PF09237.11 KZN85241.1 - 0.33 10.8 1.7 0.92 9.4 0.0 2.4 2 0 0 2 2 2 0 GAGA factor AD PF09793.9 KZN85242.1 - 9.8e-27 92.9 0.0 1.6e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain 2-Hacid_dh_C PF02826.19 KZN85243.1 - 6.5e-55 185.2 0.0 1.1e-54 184.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KZN85243.1 - 3.1e-36 124.0 0.1 5.2e-36 123.3 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.6 KZN85243.1 - 0.0019 18.7 0.0 0.005 17.3 0.0 1.7 1 0 0 1 1 1 1 XdhC Rossmann domain AlaDh_PNT_C PF01262.21 KZN85243.1 - 0.011 15.1 1.1 0.032 13.5 1.1 1.8 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 KZN85243.1 - 0.018 15.1 0.0 0.048 13.7 0.0 1.7 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 KZN85243.1 - 0.038 13.6 0.0 0.089 12.4 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 KZN85243.1 - 0.074 13.2 0.2 0.31 11.2 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.25 KZN85243.1 - 0.11 12.3 0.2 1.4 8.7 0.0 2.9 3 0 0 3 3 3 0 ACT domain Fungal_trans_2 PF11951.8 KZN85244.1 - 1.6e-07 30.5 0.5 3.8e-07 29.3 0.5 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN85244.1 - 1.1e-06 28.6 7.9 2.2e-06 27.7 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fe-ADH PF00465.19 KZN85245.1 - 9.1e-104 347.1 0.1 1.2e-103 346.8 0.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KZN85245.1 - 1.5e-14 54.3 0.0 6.4e-11 42.4 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 KZN85245.1 - 0.05 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein Bys1 PF04681.12 KZN85246.1 - 3.3e-08 33.6 0.0 4.3e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Arylsulfotran_2 PF14269.6 KZN85247.1 - 1.9e-114 382.1 9.0 2.4e-114 381.7 9.0 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Cytochrome-c551 PF10643.9 KZN85248.1 - 0.16 11.6 4.2 1.5 8.4 5.4 1.8 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 ADH_zinc_N PF00107.26 KZN85249.1 - 2.3e-24 85.8 0.3 3.5e-24 85.2 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KZN85249.1 - 3.9e-22 78.2 0.5 7.3e-22 77.3 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KZN85249.1 - 2.6e-08 35.0 0.0 5e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TPALS PF18178.1 KZN85249.1 - 0.14 11.6 0.3 0.23 10.8 0.3 1.3 1 0 0 1 1 1 0 TIR- and PNP-associating SLOG family Haem_degrading PF03928.14 KZN85251.1 - 1e-36 125.5 0.4 1.4e-36 125.2 0.4 1.2 1 0 0 1 1 1 1 Haem-degrading Pneumo_NS1 PF03438.13 KZN85251.1 - 0.1 12.8 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Pneumovirus NS1 protein MH2 PF03166.14 KZN85252.1 - 0.1 12.8 0.0 1.1 9.4 0.0 2.0 2 0 0 2 2 2 0 MH2 domain HSP70 PF00012.20 KZN85253.1 - 9.7e-258 856.3 13.9 1.1e-257 856.1 13.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KZN85253.1 - 1.5e-16 60.2 1.4 2.8e-15 55.9 0.4 2.2 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 KZN85253.1 - 0.0022 17.0 0.1 0.016 14.2 0.1 2.1 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 KZN85253.1 - 0.11 11.7 3.5 0.66 9.2 0.2 2.9 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase DUF4845 PF16137.5 KZN85253.1 - 0.4 11.6 2.7 7.2 7.5 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4845) FtsA PF14450.6 KZN85253.1 - 0.45 11.0 6.9 14 6.2 0.3 3.7 3 2 0 3 3 3 0 Cell division protein FtsA FIVAR PF07554.13 KZN85253.1 - 1.4 9.8 6.8 23 5.8 0.8 3.9 3 1 0 3 3 3 0 FIVAR domain GTP_EFTU PF00009.27 KZN85254.1 - 3.6e-49 167.0 0.0 5.9e-49 166.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 KZN85254.1 - 4.6e-19 68.5 5.3 8.7e-19 67.6 5.3 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D2 PF03144.25 KZN85254.1 - 9.4e-09 35.5 0.0 2.2e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KZN85254.1 - 1e-08 35.4 0.0 7.5e-08 32.7 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KZN85254.1 - 1e-07 32.0 0.0 2.6e-06 27.5 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KZN85254.1 - 0.00047 19.6 0.1 0.037 13.5 0.1 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KZN85254.1 - 0.00053 19.4 0.1 0.001 18.5 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KZN85254.1 - 0.0043 16.5 0.0 2.1 7.8 0.0 2.3 1 1 1 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KZN85254.1 - 0.0048 17.1 0.1 1.7 8.9 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KZN85254.1 - 0.0058 16.2 0.1 0.13 11.8 0.0 2.2 2 0 0 2 2 2 1 Ras family FeoB_N PF02421.18 KZN85254.1 - 0.022 14.3 0.4 0.75 9.3 0.2 2.9 2 1 0 2 2 2 0 Ferrous iron transport protein B BDHCT_assoc PF16204.5 KZN85254.1 - 0.026 14.2 0.5 0.067 12.9 0.5 1.6 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein Dynamin_N PF00350.23 KZN85254.1 - 0.047 13.8 0.0 6.8 6.7 0.0 3.3 2 1 1 3 3 3 0 Dynamin family Septin PF00735.18 KZN85254.1 - 0.064 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Septin Met_asp_mut_E PF06368.11 KZN85254.1 - 0.075 11.5 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) Acyltransf_C PF16076.5 KZN85254.1 - 0.14 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Acyltransferase C-terminus UCH_1 PF13423.6 KZN85255.1 - 5e-94 315.5 0.2 6.5e-94 315.1 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 KZN85255.1 - 3.8e-15 56.8 0.0 9.4e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 KZN85255.1 - 4e-05 23.2 0.0 0.00017 21.2 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Fungal_trans PF04082.18 KZN85256.1 - 2.1e-12 46.7 2.0 3e-11 42.9 2.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF2157 PF09925.9 KZN85256.1 - 0.37 10.6 1.6 0.36 10.6 0.2 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) GATase PF00117.28 KZN85257.1 - 0.0081 16.0 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Pkinase PF00069.25 KZN85258.1 - 3.8e-10 39.6 0.0 5.8e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN85258.1 - 1.3e-07 31.2 0.0 1.9e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KZN85258.1 - 0.099 12.0 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KZN85258.1 - 0.13 12.1 0.5 0.4 10.5 0.6 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family CCB1 PF12046.8 KZN85260.1 - 0.0099 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 Cofactor assembly of complex C subunit B F-box PF00646.33 KZN85260.1 - 0.33 10.9 1.5 0.56 10.2 0.3 2.0 2 0 0 2 2 2 0 F-box domain VHS PF00790.19 KZN85261.1 - 1.8e-35 121.8 1.0 3.2e-35 121.0 1.0 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 KZN85261.1 - 2.5e-16 59.0 0.0 5.7e-16 57.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KZN85261.1 - 1.6e-14 53.4 0.1 3.2e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KZN85261.1 - 7.6e-14 51.1 0.0 1.5e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 KZN85261.1 - 1.5e-09 38.0 1.7 1.5e-09 38.0 1.7 1.9 2 0 0 2 2 2 1 GAT domain Hrs_helical PF12210.8 KZN85261.1 - 0.057 14.0 0.2 0.18 12.3 0.2 1.8 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate UIM PF02809.20 KZN85261.1 - 0.1 12.6 3.3 0.27 11.2 3.3 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif Pkinase PF00069.25 KZN85262.1 - 5.9e-71 238.9 0.0 8.9e-71 238.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN85262.1 - 2e-44 151.8 0.0 3.4e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KZN85262.1 - 7.4e-22 77.5 0.7 1.7e-21 76.4 0.1 2.0 2 0 0 2 2 2 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 KZN85262.1 - 3.8e-07 29.2 0.4 1.3e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KZN85262.1 - 1.3e-06 27.9 0.0 2.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KZN85262.1 - 0.046 12.7 0.4 0.2 10.6 0.4 2.0 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KZN85262.1 - 0.053 13.4 3.4 0.41 10.5 0.1 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 KZN85262.1 - 0.067 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DSHCT PF08148.12 KZN85262.1 - 0.19 11.4 0.0 0.44 10.2 0.0 1.5 1 0 0 1 1 1 0 DSHCT (NUC185) domain S6OS1 PF15676.5 KZN85262.1 - 0.34 9.3 4.5 0.67 8.4 4.5 1.4 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family Glyco_hydro_43 PF04616.14 KZN85264.1 - 1.6e-32 113.0 6.0 2e-32 112.7 6.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 SprB PF13573.6 KZN85264.1 - 0.21 11.4 1.9 2.4 8.0 0.2 2.5 2 0 0 2 2 2 0 SprB repeat KH_1 PF00013.29 KZN85265.1 - 5.7e-93 304.8 21.7 1.2e-12 47.5 0.1 13.7 13 1 0 13 13 13 9 KH domain SLS PF14611.6 KZN85265.1 - 1.1e-13 51.6 3.3 0.77 9.5 0.0 8.8 5 2 2 8 8 8 5 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 KZN85265.1 - 2.2e-10 40.2 28.7 0.0025 17.6 0.2 7.4 7 1 1 8 8 8 5 KH domain KH_4 PF13083.6 KZN85265.1 - 0.0044 16.9 5.8 11 5.9 0.1 5.2 5 0 0 5 5 5 1 KH domain BMC PF00936.19 KZN85265.1 - 0.0068 16.4 0.1 17 5.5 0.1 4.3 4 0 0 4 4 4 1 BMC domain RL10P_insert PF17777.1 KZN85265.1 - 0.037 14.0 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Insertion domain in 60S ribosomal protein L10P KH_5 PF13184.6 KZN85265.1 - 0.056 13.5 9.6 41 4.4 0.0 6.0 6 0 0 6 6 6 0 NusA-like KH domain Acylphosphatase PF00708.18 KZN85265.1 - 0.1 13.0 1.5 3.6 8.1 0.2 3.5 3 0 0 3 3 3 0 Acylphosphatase BCAS2 PF05700.11 KZN85265.1 - 1.1 9.0 0.0 1.1 9.0 0.0 3.4 4 0 0 4 4 4 0 Breast carcinoma amplified sequence 2 (BCAS2) Cyt-b5 PF00173.28 KZN85266.1 - 1e-24 86.4 0.0 1.4e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain YqzH PF14164.6 KZN85266.1 - 0.019 15.0 0.3 0.037 14.1 0.3 1.4 1 0 0 1 1 1 0 YqzH-like protein DUF4366 PF14283.6 KZN85266.1 - 0.07 13.2 0.0 0.088 12.9 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) UCH PF00443.29 KZN85267.1 - 9.2e-52 176.1 0.0 1.3e-51 175.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KZN85267.1 - 9.6e-17 61.5 0.2 1.4e-13 51.2 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.11 KZN85267.1 - 5.1e-06 26.6 0.1 2e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 USP8 dimerisation domain Rhodanese PF00581.20 KZN85267.1 - 1.4e-05 25.5 0.0 3.4e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain VHS PF00790.19 KZN85268.1 - 2.4e-39 134.4 1.0 2e-38 131.4 0.0 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 KZN85268.1 - 5.3e-16 58.5 2.3 8.4e-16 57.9 2.3 1.3 1 0 0 1 1 1 1 FYVE zinc finger GAT PF03127.14 KZN85268.1 - 2.1e-05 24.8 0.1 6.5e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 KZN85268.1 - 3.4e-05 23.4 19.6 0.012 15.5 2.9 3.5 3 0 0 3 3 3 2 Ubiquitin interaction motif FYVE_2 PF02318.16 KZN85268.1 - 0.062 13.5 0.3 0.12 12.6 0.3 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Npa1 PF11707.8 KZN85268.1 - 0.086 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal DZR PF12773.7 KZN85268.1 - 0.22 11.6 2.4 0.47 10.5 2.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 KZN85268.1 - 0.41 10.6 2.2 0.89 9.5 2.2 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain KAAG1 PF15354.6 KZN85269.1 - 1.9 9.1 16.8 1.1 9.9 2.3 3.8 3 0 0 3 3 3 0 Kidney-associated antigen 1 PBP1_TM PF14812.6 KZN85269.1 - 2.3 8.6 8.0 2.2 8.7 3.4 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal p450 PF00067.22 KZN85270.1 - 2.3e-72 244.3 0.0 2.6e-72 244.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ion_trans_2 PF07885.16 KZN85270.1 - 0.051 13.5 0.9 0.12 12.3 0.9 1.7 1 0 0 1 1 1 0 Ion channel RCC1 PF00415.18 KZN85271.1 - 1.6e-23 83.1 0.4 1.1e-05 25.9 0.0 6.3 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KZN85271.1 - 1.1e-11 44.9 0.1 2.6e-10 40.5 0.2 2.4 2 0 0 2 2 2 1 BTB/POZ domain RCC1_2 PF13540.6 KZN85271.1 - 1.8e-11 43.5 5.8 3.2e-08 33.1 0.1 3.2 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 KZN85271.1 - 2e-10 41.0 0.2 2.8e-05 24.6 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN85271.1 - 1.9e-06 27.8 0.4 0.022 15.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KZN85271.1 - 0.00056 20.5 0.1 0.0014 19.2 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KZN85271.1 - 0.00096 19.4 0.0 0.4 11.1 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Dynamin_N PF00350.23 KZN85272.1 - 4.2e-30 105.0 0.0 9e-30 103.9 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KZN85272.1 - 3.2e-29 102.0 0.9 3.6e-21 75.6 0.3 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 KZN85272.1 - 0.00076 19.5 0.0 0.43 10.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase DNA_primase_lrg PF04104.14 KZN85272.1 - 0.45 9.9 2.8 1.7 8.0 0.0 2.9 4 0 0 4 4 4 0 Eukaryotic and archaeal DNA primase, large subunit LIP PF03583.14 KZN85274.1 - 6e-62 209.5 0.1 9.1e-62 209.0 0.1 1.2 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 KZN85274.1 - 5.4e-07 29.3 0.1 0.00053 19.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KZN85274.1 - 0.0056 16.5 0.0 0.016 15.0 0.0 1.8 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 KZN85274.1 - 0.0081 15.7 0.4 0.025 14.2 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KZN85274.1 - 0.014 14.7 0.1 0.05 12.9 0.0 1.9 3 0 0 3 3 3 0 Serine aminopeptidase, S33 ATG13 PF10033.9 KZN85275.1 - 2.7e-75 253.2 0.0 4.3e-75 252.5 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 6PGD PF00393.19 KZN85276.1 - 2.3e-128 427.6 0.0 2.7e-128 427.4 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KZN85276.1 - 2.6e-50 170.7 0.0 3.7e-50 170.2 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KZN85276.1 - 0.069 13.4 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PGK PF00162.19 KZN85276.1 - 0.19 10.6 0.0 0.3 10.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoglycerate kinase RRM_1 PF00076.22 KZN85277.1 - 1.9e-15 56.4 0.0 3.1e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 KZN85277.1 - 3.1 7.7 9.2 3.7 7.4 9.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med13_C PF06333.12 KZN85278.1 - 9.4e-87 291.3 3.1 9.4e-87 291.3 3.1 2.4 3 0 0 3 3 3 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 KZN85278.1 - 1.3e-67 228.4 0.3 2.4e-67 227.6 0.3 1.5 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 KZN85278.1 - 5.5e-32 111.5 2.6 1e-29 104.1 0.4 3.2 2 1 0 2 2 2 1 MID domain of medPIWI Rsm1 PF08600.10 KZN85278.1 - 0.074 13.2 0.0 0.24 11.6 0.0 1.8 1 0 0 1 1 1 0 Rsm1-like NUC153 PF08159.12 KZN85279.1 - 1.7e-12 46.9 0.8 3.3e-12 46.0 0.1 1.9 2 0 0 2 2 2 1 NUC153 domain WD40 PF00400.32 KZN85279.1 - 0.01 16.7 0.0 1.3e+02 3.7 0.0 4.7 5 0 0 5 5 5 0 WD domain, G-beta repeat APH PF01636.23 KZN85280.1 - 2.4e-06 27.6 0.0 5.7e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family YebG PF07130.12 KZN85280.1 - 0.16 11.9 0.5 0.34 10.8 0.5 1.5 1 0 0 1 1 1 0 YebG protein ParBc_2 PF08857.11 KZN85283.1 - 0.0019 18.3 0.2 0.9 9.6 0.0 2.2 2 0 0 2 2 2 2 Putative ParB-like nuclease DUF3990 PF13151.6 KZN85283.1 - 0.025 14.3 0.0 2.8 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3990) MgtE_N PF03448.17 KZN85283.1 - 0.025 15.2 3.8 4.1 8.1 0.3 2.3 2 0 0 2 2 2 0 MgtE intracellular N domain His_Phos_1 PF00300.22 KZN85286.1 - 5.6e-17 62.1 0.1 1.4e-15 57.5 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) HECT PF00632.25 KZN85287.1 - 4.1e-71 240.0 0.0 8e-71 239.0 0.0 1.5 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 KZN85287.1 - 1.8e-20 72.9 0.9 4.2e-20 71.7 0.9 1.7 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zf-C2H2_2 PF12756.7 KZN85288.1 - 2.3e-37 127.4 19.7 2.7e-31 107.9 5.1 3.3 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KZN85288.1 - 1.8e-06 28.1 6.5 1.8e-06 28.1 6.5 4.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KZN85288.1 - 7e-06 26.3 9.9 2.9e-05 24.3 5.3 3.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KZN85288.1 - 0.032 14.7 24.4 0.053 14.0 2.9 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type ASCH PF04266.14 KZN85288.1 - 0.037 14.6 0.0 0.1 13.2 0.0 1.7 1 0 0 1 1 1 0 ASCH domain zf-C2H2_4 PF13894.6 KZN85288.1 - 0.047 14.5 15.2 1.7 9.7 0.8 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger ALGX PF16822.5 KZN85288.1 - 0.071 12.8 1.7 0.15 11.8 1.7 1.5 1 0 0 1 1 1 0 SGNH hydrolase-like domain, acetyltransferase AlgX Ribosomal_L35p PF01632.19 KZN85288.1 - 0.62 10.6 3.8 3.4 8.2 0.2 3.1 3 0 0 3 3 3 0 Ribosomal protein L35 zf-C2H2_6 PF13912.6 KZN85288.1 - 3 7.9 12.9 2.9 8.0 0.1 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger DUF21 PF01595.20 KZN85289.1 - 5.1e-31 107.7 0.0 8.2e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KZN85289.1 - 0.0014 19.1 2.8 0.037 14.5 0.0 3.4 4 0 0 4 4 4 1 CBS domain TPR_MLP1_2 PF07926.12 KZN85290.1 - 6.2e-06 26.3 20.5 6.2e-06 26.3 20.5 5.0 4 1 1 5 5 5 2 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 KZN85290.1 - 0.0002 21.7 26.5 0.0002 21.7 26.5 3.9 2 1 2 4 4 4 1 Autophagy protein 16 (ATG16) APG6_N PF17675.1 KZN85290.1 - 0.00025 21.6 13.2 0.00025 21.6 13.2 5.5 2 2 3 5 5 5 1 Apg6 coiled-coil region DUF3450 PF11932.8 KZN85290.1 - 0.0011 18.4 9.6 0.0011 18.4 9.6 4.1 2 1 1 3 3 2 2 Protein of unknown function (DUF3450) ERM PF00769.19 KZN85290.1 - 0.0013 18.6 19.2 0.0013 18.6 19.2 3.5 1 1 1 3 3 2 1 Ezrin/radixin/moesin family THOC7 PF05615.13 KZN85290.1 - 0.0045 17.3 5.9 0.0045 17.3 5.9 5.5 2 1 1 5 5 4 1 Tho complex subunit 7 ADIP PF11559.8 KZN85290.1 - 0.0097 16.0 9.9 0.0097 16.0 9.9 5.9 2 1 4 6 6 6 2 Afadin- and alpha -actinin-Binding DUF3584 PF12128.8 KZN85290.1 - 0.6 7.6 55.8 0.12 9.8 10.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) FlxA PF14282.6 KZN85290.1 - 2.7 8.0 33.0 0.77 9.8 2.3 4.5 3 1 1 4 4 4 0 FlxA-like protein DUF5082 PF16888.5 KZN85290.1 - 2.9 8.2 27.6 1.8 8.8 3.9 4.7 3 2 1 4 4 4 0 Domain of unknown function (DUF5082) DUF948 PF06103.11 KZN85290.1 - 3.2 8.1 19.5 4.5 7.6 1.2 4.8 3 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 KZN85290.1 - 4.2 7.4 25.6 0.025 14.6 4.8 4.7 2 2 2 5 5 5 0 Protein of unknown function (DUF1664) GIT_CC PF16559.5 KZN85290.1 - 8.5 6.3 17.2 17 5.4 1.0 5.5 4 1 2 6 6 6 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1732 PF08340.11 KZN85290.1 - 8.8 6.4 16.6 1.5 8.8 2.1 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF1732) MR_MLE_C PF13378.6 KZN85291.1 - 1.6e-26 93.3 0.0 2.4e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KZN85291.1 - 1.4e-16 60.7 0.0 3.1e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain HMGL-like PF00682.19 KZN85291.1 - 0.12 11.9 0.2 0.29 10.6 0.2 1.5 1 0 0 1 1 1 0 HMGL-like Gly_transf_sug PF04488.15 KZN85292.1 - 1.4e-12 48.0 0.0 2.8e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KZN85292.1 - 0.00047 19.6 0.0 0.00078 18.9 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein AhpC-TSA PF00578.21 KZN85293.1 - 2.4e-30 105.0 0.0 3.4e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KZN85293.1 - 1.5e-13 50.7 0.0 1.9e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KZN85293.1 - 1.1e-12 47.5 0.4 1.8e-12 46.9 0.4 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.6 KZN85293.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Glyco_hydro_3_C PF01915.22 KZN85294.1 - 1e-45 156.2 0.0 3.1e-45 154.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KZN85294.1 - 2.8e-44 151.8 0.0 4.3e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KZN85294.1 - 4.1e-21 74.9 0.3 7e-21 74.1 0.3 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain MFS_1 PF07690.16 KZN85295.1 - 1.3e-43 149.3 82.6 3.8e-41 141.2 58.8 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN85295.1 - 1.2e-15 57.4 15.9 1.2e-15 57.4 15.9 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KZN85295.1 - 2e-12 46.4 30.8 3.2e-12 45.7 30.8 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.18 KZN85296.1 - 6.9e-12 44.9 0.3 1.7e-11 43.7 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN85296.1 - 1.2e-09 38.2 10.9 1.2e-09 38.2 10.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2383 PF09537.10 KZN85296.1 - 0.16 12.4 0.3 1.3 9.4 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Gp58 PF07902.11 KZN85296.1 - 0.33 9.2 1.1 0.5 8.6 1.1 1.1 1 0 0 1 1 1 0 gp58-like protein Methyltransf_25 PF13649.6 KZN85297.1 - 3.6e-10 40.4 0.0 7.8e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN85297.1 - 1e-08 35.8 0.0 2e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN85297.1 - 3.8e-08 33.4 0.0 5.1e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN85297.1 - 9.2e-08 32.0 0.0 1.3e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN85297.1 - 1.9e-05 25.2 0.0 4.4e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_PK PF05891.12 KZN85297.1 - 0.048 13.2 0.0 0.074 12.6 0.0 1.5 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Peptidase_M20 PF01546.28 KZN85298.1 - 6.7e-24 84.7 0.0 8.2e-22 77.9 0.0 2.5 2 0 0 2 2 2 2 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KZN85298.1 - 2.5e-06 27.3 0.0 4.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain WD40 PF00400.32 KZN85298.1 - 5.7e-05 23.8 16.8 0.17 12.8 0.2 6.2 6 1 0 6 6 6 2 WD domain, G-beta repeat Peptidase_M28 PF04389.17 KZN85298.1 - 0.00022 21.0 0.0 0.00057 19.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 PT PF04886.12 KZN85299.1 - 0.00036 20.0 7.3 0.00036 20.0 7.3 3.3 4 0 0 4 4 4 1 PT repeat TraQ PF09679.10 KZN85299.1 - 0.15 12.0 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) Arginosuc_synth PF00764.19 KZN85300.1 - 6.9e-159 529.3 0.0 8e-159 529.1 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KZN85300.1 - 0.0067 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KZN85300.1 - 0.016 14.0 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Transket_pyr PF02779.24 KZN85301.1 - 1.1e-43 149.0 0.0 1.8e-43 148.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KZN85301.1 - 1.7e-31 108.6 0.0 4.5e-31 107.3 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KZN85301.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II IBR PF01485.21 KZN85302.1 - 1.1e-06 28.8 7.4 1.1e-06 28.8 7.4 3.3 2 1 1 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 KZN85302.1 - 0.0054 16.7 5.3 0.0054 16.7 5.3 3.6 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KZN85302.1 - 0.011 15.6 1.7 0.011 15.6 1.7 3.0 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF2719 PF10891.8 KZN85302.1 - 0.016 15.1 0.7 0.033 14.1 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2719) zf-RING_2 PF13639.6 KZN85302.1 - 0.047 14.0 5.7 0.047 14.0 5.7 3.2 2 1 0 2 2 2 0 Ring finger domain NmrA PF05368.13 KZN85303.1 - 1.3e-23 83.8 0.0 1.8e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KZN85303.1 - 4e-20 72.5 0.0 5.2e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KZN85303.1 - 1.2e-06 28.1 0.1 2.6e-06 27.1 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KZN85303.1 - 3.4e-05 24.1 0.2 9e-05 22.7 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 KZN85303.1 - 0.0046 16.0 0.0 0.008 15.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 KZN85303.1 - 0.017 15.3 0.5 0.086 13.0 0.1 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 KZN85303.1 - 0.018 14.2 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Shikimate_DH PF01488.20 KZN85303.1 - 0.043 13.9 0.0 0.084 12.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.17 KZN85303.1 - 0.065 12.3 0.1 0.1 11.7 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 KZN85303.1 - 0.11 11.9 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase IBR PF01485.21 KZN85304.1 - 1.6e-06 28.3 24.6 4.1e-05 23.7 7.8 3.7 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain zf-RING_6 PF14835.6 KZN85304.1 - 0.0084 16.0 1.5 0.0084 16.0 1.5 3.3 3 0 0 3 3 3 1 zf-RING of BARD1-type protein SpoVT_C PF15714.5 KZN85304.1 - 0.16 12.0 2.0 2.5 8.2 0.1 3.1 4 0 0 4 4 4 0 Stage V sporulation protein T C-terminal, transcription factor DUF572 PF04502.13 KZN85305.1 - 6.6e-61 206.8 3.0 7.2e-61 206.6 3.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Filament PF00038.21 KZN85306.1 - 5.3e-06 26.2 156.0 0.0025 17.5 18.1 8.0 2 1 4 8 8 8 5 Intermediate filament protein GAS PF13851.6 KZN85306.1 - 0.0018 17.7 9.1 0.0018 17.7 9.1 8.2 1 1 5 7 7 7 3 Growth-arrest specific micro-tubule binding Pox_A_type_inc PF04508.12 KZN85306.1 - 0.27 11.2 0.0 0.27 11.2 0.0 6.5 8 0 0 8 8 8 0 Viral A-type inclusion protein repeat Spc7 PF08317.11 KZN85306.1 - 4.7 6.0 179.0 0.016 14.1 23.3 9.3 2 1 8 10 10 10 0 Spc7 kinetochore protein LAP1C PF05609.12 KZN85307.1 - 7.3 5.6 10.9 11 5.0 10.9 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PTPA PF03095.15 KZN85308.1 - 1e-116 389.6 0.0 1.2e-116 389.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Zip PF02535.22 KZN85309.1 - 1.2e-53 182.5 5.1 3.3e-53 181.1 5.1 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter HC2 PF07382.11 KZN85310.1 - 1.2 9.2 83.5 23 5.0 83.7 1.9 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 TFIIA PF03153.13 KZN85310.1 - 6.4 6.7 21.0 8 6.3 21.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IMS PF00817.20 KZN85311.1 - 4.7e-42 143.5 0.0 9.1e-42 142.6 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 KZN85311.1 - 2.9e-22 78.8 0.2 5.5e-22 78.0 0.2 1.5 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 KZN85311.1 - 1.5e-14 54.7 0.0 3.7e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain UBM PF14377.6 KZN85311.1 - 3.3e-14 51.8 16.5 2.1e-07 30.2 5.3 4.2 3 0 0 3 3 3 3 Ubiquitin binding region BRCT_2 PF16589.5 KZN85311.1 - 7.7e-10 39.1 0.0 1.6e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KZN85311.1 - 4.3e-05 23.8 0.0 0.00014 22.2 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.8 KZN85311.1 - 0.005 17.1 0.0 0.014 15.7 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif mCpol PF18182.1 KZN85311.1 - 0.0092 16.3 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 1 minimal CRISPR polymerase domain PTCB-BRCT PF12738.7 KZN85311.1 - 0.025 14.5 0.0 0.063 13.2 0.0 1.8 1 0 0 1 1 1 0 twin BRCT domain HHH_5 PF14520.6 KZN85311.1 - 0.058 14.0 0.0 0.18 12.4 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain AT_hook PF02178.19 KZN85311.1 - 0.065 13.1 3.6 0.26 11.3 3.6 2.2 1 0 0 1 1 1 0 AT hook motif Cdd1 PF11731.8 KZN85311.1 - 0.11 12.8 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Pathogenicity locus DUF1805 PF08827.11 KZN85311.1 - 0.12 12.7 0.0 0.4 11.1 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) FKBP_C PF00254.28 KZN85312.1 - 3.3e-32 110.7 0.0 1.3e-31 108.7 0.0 2.0 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 KZN85312.1 - 1.6e-29 102.5 5.5 1.6e-29 102.5 5.5 2.9 2 2 0 2 2 2 1 Nucleoplasmin-like domain Utp14 PF04615.13 KZN85312.1 - 2.8 6.4 48.3 1.4 7.4 26.0 2.1 2 0 0 2 2 2 0 Utp14 protein zf-RING_2 PF13639.6 KZN85313.1 - 6.7e-12 45.6 9.1 1e-11 44.9 9.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KZN85313.1 - 1.4e-10 40.7 3.3 2.5e-10 39.9 3.3 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KZN85313.1 - 3.2e-09 36.5 9.2 4.9e-09 35.9 9.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KZN85313.1 - 1.2e-07 31.9 7.7 2.4e-07 30.9 7.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KZN85313.1 - 7.2e-07 29.0 4.2 1.1e-06 28.4 4.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KZN85313.1 - 1.2e-05 25.0 8.1 2e-05 24.4 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KZN85313.1 - 0.00013 21.8 5.8 0.0002 21.2 5.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KZN85313.1 - 0.00015 21.7 4.3 0.00032 20.7 4.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KZN85313.1 - 0.00078 19.2 6.0 0.0014 18.4 6.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KZN85313.1 - 0.0011 19.0 2.9 0.0021 18.1 2.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KZN85313.1 - 0.12 12.0 8.3 0.2 11.3 8.3 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KZN85313.1 - 0.17 11.7 3.5 0.3 10.9 3.5 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 KZN85313.1 - 0.2 11.8 0.4 0.42 10.8 0.4 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING-like PF08746.11 KZN85313.1 - 0.7 10.2 7.4 1.1 9.7 7.4 1.3 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 KZN85313.1 - 0.7 9.8 6.0 1.2 9.0 6.0 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 KZN85313.1 - 0.85 9.8 6.0 1.8 8.8 6.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 KZN85313.1 - 4.8 7.4 7.9 12 6.2 7.9 1.6 1 1 0 1 1 1 0 RING-variant domain Peptidase_M3 PF01432.20 KZN85315.1 - 2.6e-118 396.2 0.0 3.9e-118 395.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 KZN85315.1 - 0.046 14.0 0.0 0.084 13.2 0.0 1.3 1 0 0 1 1 1 0 Effector protein ApoO PF09769.9 KZN85316.1 - 4.9e-39 133.3 1.2 1.3e-38 131.9 0.2 2.0 3 0 0 3 3 3 1 Apolipoprotein O GRASP55_65 PF04495.14 KZN85317.1 - 7.7e-41 139.6 0.0 9.8e-40 136.1 0.0 2.0 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 KZN85317.1 - 0.0023 17.7 0.0 0.72 9.8 0.0 2.8 2 0 0 2 2 2 2 PDZ domain Methyltransf_15 PF09445.10 KZN85318.1 - 7.9e-51 171.9 0.0 9.9e-51 171.6 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 KZN85318.1 - 7.1e-10 39.0 0.0 8.7e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 KZN85318.1 - 3e-07 30.3 0.0 4.1e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 KZN85318.1 - 4.2e-06 26.6 0.0 6.7e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 KZN85318.1 - 0.00051 19.9 0.0 0.00065 19.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KZN85318.1 - 0.0015 18.5 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 KZN85318.1 - 0.0026 17.1 0.0 0.0035 16.7 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_25 PF13649.6 KZN85318.1 - 0.0058 17.3 0.0 0.01 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KZN85318.1 - 0.013 14.7 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_11 PF08241.12 KZN85318.1 - 0.026 15.1 0.0 0.054 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_5 PF01795.19 KZN85318.1 - 0.038 13.5 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family DUF3591 PF12157.8 KZN85319.1 - 1.9e-175 583.8 0.4 2.7e-175 583.3 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 KZN85319.1 - 0.0053 16.8 0.7 0.0088 16.1 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 KZN85319.1 - 0.0067 16.2 1.2 0.016 15.0 1.2 1.6 1 0 0 1 1 1 1 Zinc knuckle Pkinase PF00069.25 KZN85320.1 - 8.1e-48 163.1 0.1 8.8e-26 90.8 0.0 3.2 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KZN85320.1 - 1.4e-20 73.7 0.0 4.8e-12 45.7 0.0 2.7 2 1 1 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KZN85320.1 - 0.00045 20.2 0.6 0.0016 18.4 0.3 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Orbi_NS1 PF01718.16 KZN85320.1 - 0.043 12.3 0.0 0.068 11.6 0.0 1.2 1 0 0 1 1 1 0 Orbivirus non-structural protein NS1, or hydrophobic tubular protein Haspin_kinase PF12330.8 KZN85320.1 - 0.059 12.3 0.1 0.095 11.6 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KZN85320.1 - 0.19 10.6 0.0 0.38 9.7 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase AAA PF00004.29 KZN85321.1 - 5.1e-17 62.5 0.0 9.8e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KZN85321.1 - 0.001 19.4 0.1 0.0044 17.4 0.0 2.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KZN85321.1 - 0.0017 18.7 0.6 0.021 15.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 KZN85321.1 - 0.046 13.4 0.1 0.083 12.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KZN85321.1 - 0.08 12.9 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KZN85321.1 - 0.12 12.7 0.1 0.25 11.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.18 KZN85322.1 - 6.5e-36 123.7 0.0 1.1e-35 123.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN85323.1 - 3.2e-05 24.0 10.3 4.7e-05 23.4 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MSC PF09402.10 KZN85324.1 - 1.2e-107 360.3 0.0 1.5e-107 360.0 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 KZN85324.1 - 2e-16 59.4 0.0 3.7e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 HeH/LEM domain PP2C PF00481.21 KZN85325.1 - 1.6e-51 175.4 0.0 2.5e-51 174.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 KZN85325.1 - 9.2e-33 111.8 62.7 2.8e-06 27.0 0.7 11.1 5 3 7 13 13 13 11 Leucine rich repeat LRR_4 PF12799.7 KZN85325.1 - 7.9e-32 108.8 63.0 0.0001 22.6 1.0 12.6 8 2 4 13 13 13 11 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 KZN85325.1 - 7.7e-26 90.8 0.0 1.6e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_9 PF14580.6 KZN85325.1 - 6.7e-06 25.7 12.0 0.027 14.0 0.1 4.3 2 1 1 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 KZN85325.1 - 2e-05 24.5 58.3 9.9 7.2 0.7 15.4 15 2 0 15 15 15 3 Leucine Rich Repeat LRR_5 PF13306.6 KZN85325.1 - 7.1e-05 22.8 8.1 0.71 9.8 0.2 4.6 3 2 1 4 4 4 3 BspA type Leucine rich repeat region (6 copies) Ad_cyc_g-alpha PF08509.11 KZN85325.1 - 0.00061 19.4 0.1 0.0027 17.4 0.1 2.1 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain Glyco_hydro_16 PF00722.21 KZN85326.1 - 1.9e-45 154.5 4.7 1.9e-45 154.5 4.7 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 RRN3 PF05327.11 KZN85327.1 - 0.11 11.0 4.6 0.17 10.4 4.6 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 KZN85327.1 - 0.6 9.5 10.3 0.76 9.1 10.3 1.1 1 0 0 1 1 1 0 SDA1 TFIIA PF03153.13 KZN85327.1 - 0.74 9.7 14.3 0.96 9.4 14.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DNA_pol_phi PF04931.13 KZN85327.1 - 4 5.4 17.0 5.1 5.1 17.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi ABC_membrane PF00664.23 KZN85328.1 - 4.3e-99 331.6 35.7 7.1e-51 173.5 9.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KZN85328.1 - 4.2e-72 241.1 0.0 1.2e-34 119.8 0.0 2.9 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 KZN85328.1 - 1.3e-12 47.6 0.0 0.00083 18.9 0.0 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KZN85328.1 - 1.2e-06 28.5 0.0 0.015 15.0 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KZN85328.1 - 3.5e-06 26.7 0.5 0.037 13.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KZN85328.1 - 4.2e-06 27.2 3.0 0.081 13.3 0.4 3.6 2 2 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KZN85328.1 - 4.4e-06 26.7 0.0 0.16 11.9 0.0 3.3 3 0 0 3 3 3 2 RsgA GTPase ABC_ATPase PF09818.9 KZN85328.1 - 5.6e-06 25.4 1.5 0.084 11.7 0.1 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_21 PF13304.6 KZN85328.1 - 1.6e-05 24.9 1.7 0.069 12.9 0.1 3.9 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KZN85328.1 - 3.2e-05 24.2 1.8 0.54 10.5 0.1 3.8 2 2 0 2 2 2 2 AAA domain AAA PF00004.29 KZN85328.1 - 0.00029 21.2 1.1 4.3 7.8 0.2 4.7 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) PRK PF00485.18 KZN85328.1 - 0.00033 20.5 0.0 0.14 11.9 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KZN85328.1 - 0.00057 20.4 0.0 1 9.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 KZN85328.1 - 0.00064 19.4 0.8 1.4 8.5 0.0 3.1 3 0 0 3 3 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.14 KZN85328.1 - 0.00083 19.4 0.2 3.4 7.7 0.0 3.5 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 KZN85328.1 - 0.0009 18.6 0.0 0.25 10.6 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.6 KZN85328.1 - 0.0011 19.5 0.3 0.44 11.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KZN85328.1 - 0.0011 19.2 0.4 1.8 8.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KZN85328.1 - 0.0017 18.1 0.1 0.34 10.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KZN85328.1 - 0.0023 18.0 0.6 0.75 9.8 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain SbcCD_C PF13558.6 KZN85328.1 - 0.003 17.7 4.5 0.67 10.2 0.5 4.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.6 KZN85328.1 - 0.0038 17.2 0.0 9.2 6.3 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KZN85328.1 - 0.004 16.9 3.4 0.96 9.1 0.2 3.6 3 1 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 KZN85328.1 - 0.0056 16.8 0.1 5.3 7.2 0.0 3.5 3 0 0 3 3 3 0 50S ribosome-binding GTPase Mg_chelatase PF01078.21 KZN85328.1 - 0.0078 15.6 0.0 0.7 9.2 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KZN85328.1 - 0.014 15.7 0.0 8.8 6.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 KZN85328.1 - 0.016 14.4 0.4 3.9 6.6 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.6 KZN85328.1 - 0.016 15.3 0.0 5.6 7.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KZN85328.1 - 0.026 14.4 0.1 1.4 8.8 0.0 2.6 3 0 0 3 3 2 0 Rad17 P-loop domain AAA_25 PF13481.6 KZN85328.1 - 0.029 13.9 6.2 0.2 11.2 0.1 3.5 4 0 0 4 4 3 0 AAA domain Dala_Dala_lig_N PF01820.21 KZN85328.1 - 0.039 14.4 0.0 10 6.6 0.0 2.8 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus APS_kinase PF01583.20 KZN85328.1 - 0.043 13.7 0.6 13 5.6 0.0 2.7 3 0 0 3 3 2 0 Adenylylsulphate kinase G-alpha PF00503.20 KZN85328.1 - 0.063 12.4 0.0 4.1 6.5 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit AAA_7 PF12775.7 KZN85328.1 - 0.079 12.5 0.1 3 7.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase PF06745.13 KZN85328.1 - 0.22 10.8 1.5 0.57 9.5 0.1 2.1 2 0 0 2 2 2 0 KaiC Cys_Met_Meta_PP PF01053.20 KZN85329.1 - 3.4e-92 308.9 0.0 3.9e-92 308.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KZN85329.1 - 4.3e-07 29.2 0.0 6.5e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KZN85329.1 - 0.00014 21.2 0.0 0.00024 20.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 KZN85329.1 - 0.086 11.3 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase bZIP_1 PF00170.21 KZN85330.1 - 1.5e-05 25.0 1.2 3.1e-05 24.0 1.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor Aminotran_5 PF00266.19 KZN85331.1 - 3.9e-19 68.9 0.0 1.1e-18 67.4 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KZN85331.1 - 0.00062 19.0 0.0 0.0012 18.1 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KZN85331.1 - 0.022 14.1 0.1 0.72 9.1 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Fis1_TPR_C PF14853.6 KZN85332.1 - 2.9e-25 88.1 0.5 4.6e-25 87.5 0.5 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KZN85332.1 - 2.5e-16 59.0 0.1 4.1e-16 58.3 0.1 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 KZN85332.1 - 0.012 15.7 1.4 0.012 15.7 1.4 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Spc24 PF08286.11 KZN85333.1 - 3.2e-36 123.8 1.6 4.5e-35 120.1 0.1 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 CLZ PF16526.5 KZN85333.1 - 0.059 13.7 7.3 1.4 9.3 1.2 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4559 PF15112.6 KZN85333.1 - 0.089 12.5 0.8 0.11 12.1 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Prefoldin_2 PF01920.20 KZN85333.1 - 0.096 12.6 2.7 7.9 6.5 1.9 2.2 2 0 0 2 2 2 0 Prefoldin subunit DUF4795 PF16043.5 KZN85333.1 - 0.11 12.0 4.4 0.53 9.9 4.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) APG6_N PF17675.1 KZN85333.1 - 0.16 12.5 10.5 0.23 12.0 10.5 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 KZN85333.1 - 1.1 9.3 11.1 0.52 10.4 2.6 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2034 PF10356.9 KZN85334.1 - 3.6e-42 143.9 0.0 4.1e-26 91.6 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 KZN85334.1 - 1.9e-07 31.1 0.0 3.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease Med21 PF11221.8 KZN85335.1 - 1.4e-59 200.5 6.1 1.7e-57 193.7 6.1 2.0 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.13 KZN85335.1 - 0.0093 16.0 0.8 0.048 13.7 0.8 2.2 1 1 1 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 APG6_N PF17675.1 KZN85335.1 - 0.014 15.9 0.4 0.045 14.3 0.6 1.6 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4455 PF14643.6 KZN85335.1 - 0.026 13.2 0.2 0.037 12.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) DUF4515 PF14988.6 KZN85335.1 - 0.062 13.1 0.7 0.1 12.5 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) SNF2_N PF00176.23 KZN85336.1 - 6.5e-64 215.9 0.1 9.6e-64 215.3 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KZN85336.1 - 3.3e-11 43.5 0.0 1.2e-10 41.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KZN85336.1 - 2.8e-06 27.2 0.0 8.1e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KZN85336.1 - 3.5e-06 27.1 0.0 7.7e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 KZN85336.1 - 0.01 15.7 1.5 0.018 15.0 1.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KZN85336.1 - 0.71 9.8 2.7 1.8 8.5 2.6 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KZN85336.1 - 0.86 9.5 2.4 1.7 8.5 2.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PI3_PI4_kinase PF00454.27 KZN85337.1 - 1.3e-43 149.6 0.0 1.9e-43 149.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase GATA PF00320.27 KZN85338.1 - 1.5e-15 56.5 2.6 2.5e-15 55.8 2.6 1.4 1 0 0 1 1 1 1 GATA zinc finger Pox_A_type_inc PF04508.12 KZN85338.1 - 2.1e-05 24.2 2.9 0.011 15.6 0.8 3.4 3 0 0 3 3 3 2 Viral A-type inclusion protein repeat CENP-F_N PF10481.9 KZN85338.1 - 0.0046 16.6 2.0 0.034 13.8 0.1 2.1 1 1 0 2 2 2 1 Cenp-F N-terminal domain TF_Zn_Ribbon PF08271.12 KZN85338.1 - 0.011 15.2 0.6 0.023 14.2 0.6 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding DivIVA PF05103.13 KZN85338.1 - 0.071 13.2 1.3 0.71 10.0 1.3 2.0 1 1 0 1 1 1 0 DivIVA protein CLZ PF16526.5 KZN85338.1 - 0.15 12.4 4.9 3.4 8.1 1.5 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ArfGap PF01412.18 KZN85338.1 - 0.17 12.0 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf CENP-F_leu_zip PF10473.9 KZN85338.1 - 0.17 11.9 4.7 6.9 6.7 1.6 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_2 PF07716.15 KZN85338.1 - 0.88 9.7 8.5 4.5 7.4 0.1 2.5 2 0 0 2 2 2 0 Basic region leucine zipper Nodulin-like PF06813.13 KZN85339.1 - 1.8e-24 86.6 0.7 3.7e-24 85.6 0.7 1.5 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.16 KZN85339.1 - 2.9e-15 56.1 28.8 2.9e-15 56.1 28.8 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Serinc PF03348.15 KZN85340.1 - 4.5e-159 530.0 14.9 5.1e-159 529.8 14.9 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF21 PF01595.20 KZN85340.1 - 9.1 5.9 18.1 0.056 13.1 2.5 3.8 2 1 2 4 4 4 0 Cyclin M transmembrane N-terminal domain MutL_C PF08676.11 KZN85341.1 - 5.5e-24 84.6 0.0 1.4e-23 83.3 0.0 1.7 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KZN85341.1 - 3.9e-18 65.2 0.0 3.5e-17 62.2 0.0 2.6 3 0 0 3 3 3 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KZN85341.1 - 2e-11 43.9 0.0 9.1e-11 41.7 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KZN85341.1 - 2.3e-06 28.1 0.0 1e-05 26.0 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GCN5L1 PF06320.13 KZN85342.1 - 7.8e-20 71.1 1.7 1.3e-19 70.4 1.7 1.3 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) APH PF01636.23 KZN85342.1 - 0.11 12.4 5.1 0.94 9.3 5.2 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family Mannosyl_trans3 PF11051.8 KZN85343.1 - 4.3e-56 190.3 0.0 2e-55 188.1 0.0 2.0 1 1 0 1 1 1 1 Mannosyltransferase putative Sugar_tr PF00083.24 KZN85345.1 - 1.1e-94 317.9 17.5 1.2e-94 317.8 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN85345.1 - 5.7e-28 97.9 44.0 9.5e-25 87.2 16.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KZN85345.1 - 0.0047 15.4 1.0 0.0047 15.4 1.0 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) VIT1 PF01988.19 KZN85345.1 - 0.34 10.7 3.8 1.3 8.8 0.2 3.0 3 0 0 3 3 3 0 VIT family VIR_N PF15912.5 KZN85347.1 - 0.42 10.2 6.5 0.47 10.0 6.5 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal PRIMA1 PF16101.5 KZN85347.1 - 0.99 9.5 8.0 1.8 8.6 8.0 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 KZN85347.1 - 2 8.5 11.0 0.56 10.2 8.3 1.5 1 1 0 1 1 1 0 Mitochondrial fission regulator NeA_P2 PF12312.8 KZN85347.1 - 5.6 6.3 9.5 2.8 7.3 8.1 1.3 1 1 0 1 1 1 0 Nepovirus subgroup A polyprotein Chitin_synth_2 PF03142.15 KZN85348.1 - 2.1e-241 802.1 1.3 3e-241 801.6 1.3 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KZN85348.1 - 3.3e-73 247.1 0.0 3e-72 243.9 0.0 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 KZN85348.1 - 4.2e-15 55.6 0.1 1.8e-11 44.0 0.0 2.8 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 KZN85348.1 - 5.9e-15 54.9 0.1 7.5e-14 51.4 0.4 2.5 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.6 KZN85348.1 - 1.2e-09 38.4 0.0 3.3e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KZN85348.1 - 1.7e-09 37.9 6.8 5.3e-09 36.3 6.8 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 RsgA_GTPase PF03193.16 KZN85348.1 - 0.051 13.5 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KZN85348.1 - 0.055 13.8 0.1 0.19 12.1 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain Glycos_transf_2 PF00535.26 KZN85348.1 - 0.075 12.8 0.0 2.6 7.8 0.0 2.6 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KZN85348.1 - 0.17 11.3 0.1 0.58 9.6 0.1 1.9 1 1 0 1 1 1 0 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 KZN85349.1 - 6.9e-230 764.1 0.0 9.5e-230 763.7 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase DEK_C PF08766.11 KZN85349.1 - 2.1e-16 59.5 0.5 5.9e-16 58.1 0.5 1.8 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 KZN85349.1 - 1.8e-12 47.6 3.3 1.8e-12 47.6 3.3 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KZN85349.1 - 1.2e-11 45.0 0.0 2.5e-10 40.7 0.1 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.28 KZN85349.1 - 4.4e-11 42.8 0.9 2.2e-06 27.7 0.1 3.0 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Myosin_head PF00063.21 KZN85349.1 - 4.5e-09 35.1 0.0 3e-08 32.4 0.0 1.9 1 1 0 2 2 2 1 Myosin head (motor domain) Glyco_transf_21 PF13506.6 KZN85349.1 - 0.0012 18.4 0.0 0.0076 15.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KZN85349.1 - 0.0086 15.9 0.0 0.26 11.1 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Jiv90 PF14901.6 KZN85349.1 - 0.02 15.1 3.5 4.7 7.4 0.5 2.7 2 1 0 2 2 2 0 Cleavage inducing molecular chaperone Glyco_hydro_2_N PF02837.18 KZN85350.1 - 5.8e-14 52.3 0.0 1.5e-13 51.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 KZN85350.1 - 1.4e-12 47.4 0.1 4e-11 42.6 0.1 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 KZN85350.1 - 1.1e-06 29.3 0.0 2.4e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2 KH_1 PF00013.29 KZN85351.1 - 1.8e-32 111.0 3.7 1.2e-08 34.6 0.0 6.5 6 0 0 6 6 6 5 KH domain HNH_2 PF13391.6 KZN85352.1 - 4e-07 30.1 0.1 1e-06 28.8 0.1 1.7 2 0 0 2 2 2 1 HNH endonuclease Hydrolase PF00702.26 KZN85354.1 - 1.5e-07 31.9 0.0 1.9e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KZN85354.1 - 1.6e-06 28.3 0.0 2.3e-06 27.8 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KZN85354.1 - 0.051 13.6 0.0 0.086 12.9 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Dynactin PF12455.8 KZN85355.1 - 4.7e-89 298.4 12.5 4.7e-89 298.4 12.5 4.9 4 1 0 5 5 5 1 Dynein associated protein CAP_GLY PF01302.25 KZN85355.1 - 1.3e-23 82.8 0.1 2.3e-23 82.0 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF2353 PF09789.9 KZN85355.1 - 0.00043 19.7 26.9 0.00043 19.7 26.9 3.9 3 1 1 4 4 4 2 Uncharacterized coiled-coil protein (DUF2353) Rootletin PF15035.6 KZN85355.1 - 0.0048 17.0 4.8 0.0048 17.0 4.8 5.4 2 2 2 4 4 4 1 Ciliary rootlet component, centrosome cohesion GAS PF13851.6 KZN85355.1 - 0.0054 16.1 11.5 0.0054 16.1 11.5 6.2 3 1 3 6 6 6 1 Growth-arrest specific micro-tubule binding DUF3138 PF11336.8 KZN85355.1 - 9.1 4.8 9.7 2.8 6.5 3.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Solute_trans_a PF03619.16 KZN85357.1 - 6.8e-94 314.3 5.1 8.7e-94 313.9 5.1 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Aminotran_1_2 PF00155.21 KZN85359.1 - 1.3e-17 64.0 0.0 1.7e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KZN85359.1 - 0.00032 19.6 0.0 0.00066 18.6 0.0 1.4 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase TPP_enzyme_N PF02776.18 KZN85360.1 - 1.3e-39 135.6 0.0 5.8e-39 133.5 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KZN85360.1 - 8.8e-21 74.3 0.0 1.9e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KZN85360.1 - 4.7e-16 58.8 0.1 2.6e-15 56.3 0.0 2.4 4 0 0 4 4 4 1 Thiamine pyrophosphate enzyme, central domain DUF2235 PF09994.9 KZN85361.1 - 1.2e-77 261.1 0.0 1.7e-77 260.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) APH PF01636.23 KZN85362.1 - 5.5e-06 26.5 0.2 1e-05 25.6 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN85362.1 - 0.004 16.8 0.0 0.0061 16.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase PLDc_2 PF13091.6 KZN85363.1 - 8.3e-19 67.8 0.1 2e-11 43.9 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KZN85363.1 - 0.0016 18.5 0.1 0.11 12.7 0.0 2.8 2 0 0 2 2 2 1 Phospholipase D Active site motif Regulator_TrmB PF11495.8 KZN85363.1 - 0.039 13.1 0.0 0.13 11.5 0.0 1.8 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB Fer4_19 PF06902.11 KZN85363.1 - 0.13 12.4 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 Divergent 4Fe-4S mono-cluster MmgE_PrpD PF03972.14 KZN85364.1 - 7.9e-110 367.4 0.0 9e-110 367.2 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family BCDHK_Adom3 PF10436.9 KZN85365.1 - 8.6e-46 155.7 0.0 1.1e-45 155.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KZN85365.1 - 1.6e-12 47.9 0.0 3.8e-12 46.7 0.0 1.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KZN85365.1 - 0.18 11.8 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Inhibitor_I9 PF05922.16 KZN85366.1 - 0.0042 17.7 0.0 0.0044 17.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF1989 PF09347.10 KZN85367.1 - 4e-61 205.5 0.0 5.2e-61 205.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) DSPc PF00782.20 KZN85368.1 - 3.6e-21 75.4 0.0 4e-16 59.0 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KZN85368.1 - 0.0045 16.6 0.1 0.0089 15.6 0.0 1.6 1 1 0 1 1 1 1 Protein-tyrosine phosphatase RIBIOP_C PF04950.12 KZN85369.1 - 1.6e-94 316.7 0.0 1.6e-94 316.7 0.0 1.9 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KZN85369.1 - 1.1e-28 99.1 0.0 4.1e-28 97.3 0.0 2.1 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 KZN85369.1 - 3.3e-05 24.2 0.4 9.6e-05 22.7 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 KZN85369.1 - 9.8e-05 22.8 0.0 0.0003 21.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KZN85369.1 - 0.00035 21.1 0.6 0.0013 19.3 0.0 2.2 2 0 0 2 2 1 1 ABC transporter AAA_33 PF13671.6 KZN85369.1 - 0.00036 20.7 1.6 0.00047 20.3 0.0 2.1 2 0 0 2 2 1 1 AAA domain GTP_EFTU PF00009.27 KZN85369.1 - 0.00064 19.3 0.0 0.12 11.9 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KZN85369.1 - 0.00079 19.5 0.0 0.0022 18.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 KZN85369.1 - 0.0017 18.3 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 KZN85369.1 - 0.002 18.5 0.0 0.0039 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KZN85369.1 - 0.0032 17.9 0.0 0.0075 16.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KZN85369.1 - 0.0094 15.2 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain cobW PF02492.19 KZN85369.1 - 0.013 15.1 0.1 0.025 14.2 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KZN85369.1 - 0.017 14.9 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KZN85369.1 - 0.021 15.1 0.1 0.07 13.4 0.1 2.0 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KZN85369.1 - 0.023 15.1 0.0 0.056 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 KZN85369.1 - 0.023 14.4 0.1 0.071 12.8 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KZN85369.1 - 0.032 14.2 0.0 0.092 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KZN85369.1 - 0.043 14.4 0.0 0.043 14.4 0.0 3.2 3 1 0 3 3 3 0 AAA domain MobB PF03205.14 KZN85369.1 - 0.043 13.7 0.1 0.16 11.9 0.1 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 KZN85369.1 - 0.044 13.7 0.3 0.087 12.7 0.3 1.5 1 0 0 1 1 1 0 NTPase ATPase_2 PF01637.18 KZN85369.1 - 0.052 13.4 1.4 0.071 13.0 0.0 1.8 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KZN85369.1 - 0.053 13.5 0.1 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Roc PF08477.13 KZN85369.1 - 0.055 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 KZN85369.1 - 0.06 12.9 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region KAP_NTPase PF07693.14 KZN85369.1 - 0.064 12.5 0.6 0.09 12.0 0.0 1.5 2 0 0 2 2 1 0 KAP family P-loop domain RsgA_GTPase PF03193.16 KZN85369.1 - 0.072 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 KZN85369.1 - 0.083 12.5 0.0 0.25 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KZN85369.1 - 0.087 12.6 0.1 0.82 9.4 0.1 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 KZN85369.1 - 0.087 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TsaE PF02367.17 KZN85369.1 - 0.092 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 KZN85369.1 - 0.14 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_11 PF13086.6 KZN85369.1 - 0.24 11.2 0.0 0.24 11.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_21 PF13304.6 KZN85369.1 - 4.8 6.9 9.5 4.2 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF573 PF04504.14 KZN85370.1 - 0.067 13.8 0.0 0.09 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF573 MFS_1 PF07690.16 KZN85372.1 - 4.2e-43 147.6 26.2 4.2e-43 147.6 26.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KZN85372.1 - 2.9e-09 35.9 1.0 2.9e-09 35.9 1.0 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KZN85372.1 - 3.7e-06 26.1 19.5 1.3e-05 24.3 19.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3784 PF12650.7 KZN85372.1 - 0.21 11.8 0.2 0.21 11.8 0.2 4.7 4 3 2 6 6 6 0 Domain of unknown function (DUF3784) DUF1772 PF08592.11 KZN85372.1 - 3.2 8.1 20.4 0.72 10.2 0.5 4.4 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) Fungal_trans PF04082.18 KZN85373.1 - 5.2e-18 65.0 0.0 8.2e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KZN85373.1 - 4.5e-08 33.2 10.5 1.6e-07 31.5 2.2 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KZN85373.1 - 2.3e-07 30.9 10.0 0.0046 17.3 0.3 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KZN85373.1 - 9.3e-05 23.0 9.6 0.098 13.5 0.3 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zinc_ribbon_9 PF14369.6 KZN85373.1 - 0.25 11.7 2.3 0.72 10.2 2.3 1.8 1 0 0 1 1 1 0 zinc-ribbon zf-C2HE PF16278.5 KZN85373.1 - 0.4 11.2 4.7 5.9 7.4 1.5 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2H2_ZHX PF18387.1 KZN85373.1 - 0.6 9.8 4.1 2.6 7.8 0.1 2.5 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_11 PF16622.5 KZN85373.1 - 6.2 6.7 7.1 33 4.3 0.1 3.1 2 0 0 2 2 2 0 zinc-finger C2H2-type Methyltransf_24 PF13578.6 KZN85374.1 - 4.5e-14 53.3 0.0 7.3e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KZN85374.1 - 1.3e-05 24.5 0.0 2.8e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase DUF1442 PF07279.11 KZN85374.1 - 0.0001 21.7 0.0 0.00014 21.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1442) CmcI PF04989.12 KZN85374.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.6 1 1 0 1 1 1 0 Cephalosporin hydroxylase Glyoxalase PF00903.25 KZN85375.1 - 1.6e-13 51.0 0.0 2.2e-12 47.3 0.0 2.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KZN85375.1 - 2.6e-06 27.6 0.0 6.4e-05 23.2 0.0 2.5 2 1 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KZN85375.1 - 0.0027 18.5 0.0 0.027 15.3 0.0 2.4 2 1 0 2 2 2 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KZN85375.1 - 0.15 12.0 0.0 40 4.2 0.0 2.9 3 0 0 3 3 3 0 Glyoxalase-like domain TxDE PF18711.1 KZN85375.1 - 0.18 11.9 0.0 0.43 10.8 0.0 1.7 1 0 0 1 1 1 0 Toxoflavin-degrading enzyme PWI PF01480.17 KZN85376.1 - 1e-11 45.0 0.2 3.3e-11 43.3 0.0 1.9 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.22 KZN85376.1 - 1e-06 28.5 0.3 4.7e-05 23.1 0.1 2.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KZN85376.1 - 3.2e-06 27.0 0.0 0.00013 21.9 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KZN85376.1 - 0.0032 17.3 0.0 0.0086 15.9 0.0 1.7 1 0 0 1 1 1 1 Occluded RNA-recognition motif zf-CCCH PF00642.24 KZN85376.1 - 0.0096 15.8 2.0 0.018 15.0 2.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) GRP PF07172.11 KZN85376.1 - 0.027 15.1 9.9 0.027 15.1 9.9 4.0 4 0 0 4 4 4 0 Glycine rich protein family RRM_3 PF08777.11 KZN85376.1 - 1.3 9.1 5.8 0.96 9.5 0.8 2.6 1 1 1 2 2 2 0 RNA binding motif DUF4407 PF14362.6 KZN85376.1 - 1.6 8.0 13.0 2.6 7.3 13.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Borrelia_P83 PF05262.11 KZN85376.1 - 1.9 6.9 12.4 2.8 6.4 12.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein GTP_EFTU PF00009.27 KZN85377.1 - 1.4e-65 220.5 0.0 2e-65 220.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KZN85377.1 - 2e-34 118.0 0.0 6.2e-34 116.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KZN85377.1 - 3.1e-22 78.4 0.0 1.4e-21 76.4 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 KZN85377.1 - 2.1e-12 46.9 0.0 6e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KZN85377.1 - 1e-10 41.8 0.5 3.3e-10 40.2 0.1 2.1 2 1 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KZN85377.1 - 0.00034 20.7 0.0 0.00074 19.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MFS_1 PF07690.16 KZN85378.1 - 3.5e-33 115.0 60.9 7.3e-29 100.8 39.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN85378.1 - 0.0043 16.0 29.9 0.075 11.9 12.7 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter Aminotran_4 PF01063.19 KZN85379.1 - 5.2e-29 101.7 0.0 8.4e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Amino-transferase class IV HTH_Tnp_Tc5 PF03221.16 KZN85380.1 - 0.013 15.5 0.0 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain Pkinase PF00069.25 KZN85382.1 - 1.1e-57 195.4 0.0 1.5e-57 195.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN85382.1 - 4.7e-43 147.3 0.0 6.8e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KZN85382.1 - 5.5e-05 22.6 0.0 8.2e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KZN85382.1 - 0.00066 18.6 0.2 0.0022 16.8 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KZN85382.1 - 0.0025 17.2 0.1 0.0066 15.8 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KZN85382.1 - 0.0042 17.0 0.0 0.062 13.2 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 KZN85382.1 - 0.035 13.7 0.0 0.099 12.3 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KZN85382.1 - 0.036 13.7 0.1 0.11 12.0 0.1 1.8 1 1 0 1 1 1 0 RIO1 family Pkinase PF00069.25 KZN85385.1 - 6.5e-70 235.5 0.0 9.1e-70 235.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN85385.1 - 2.2e-36 125.5 0.0 3.2e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KZN85385.1 - 1.3e-05 24.7 0.0 1.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KZN85385.1 - 0.00045 19.1 0.0 0.00092 18.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KZN85385.1 - 0.0018 17.6 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KZN85385.1 - 0.015 14.9 0.1 0.047 13.2 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL UQ_con PF00179.26 KZN85386.1 - 3.3e-25 88.4 0.1 3.6e-25 88.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KZN85386.1 - 6.5e-06 25.9 0.0 1.2e-05 25.1 0.0 1.5 1 1 1 2 2 2 1 Prokaryotic E2 family B RWD PF05773.22 KZN85386.1 - 0.00041 20.6 0.1 0.0024 18.2 0.0 1.9 1 1 1 2 2 2 1 RWD domain Aminotran_1_2 PF00155.21 KZN85387.1 - 1.3e-24 87.1 0.0 1.5e-24 86.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KZN85387.1 - 0.17 10.7 0.0 0.34 9.7 0.0 1.4 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Surface_Ag_2 PF01617.17 KZN85387.1 - 0.2 11.0 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Surface antigen DUF3455 PF11937.8 KZN85388.1 - 1.1e-44 152.7 0.0 1.5e-44 152.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) SF3b1 PF08920.10 KZN85389.1 - 1.5e-23 83.5 0.6 3.9e-23 82.2 0.6 1.7 1 0 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 KZN85389.1 - 2.8e-13 50.1 9.0 0.53 10.7 0.0 8.1 6 1 3 9 9 9 6 HEAT repeats HEAT_EZ PF13513.6 KZN85389.1 - 2.2e-12 47.2 1.1 0.071 13.6 0.0 7.1 7 0 0 7 7 7 3 HEAT-like repeat HEAT PF02985.22 KZN85389.1 - 2.2e-08 33.6 12.2 0.12 12.7 0.3 8.6 9 0 0 9 9 8 2 HEAT repeat Cnd1 PF12717.7 KZN85389.1 - 2.4e-08 34.2 2.2 0.32 11.0 0.0 6.5 5 2 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KZN85389.1 - 1.9e-05 25.2 0.2 2.4 8.8 0.0 4.9 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region NUC173 PF08161.12 KZN85389.1 - 0.0045 16.7 0.1 0.91 9.1 0.0 4.2 5 0 0 5 5 5 1 NUC173 domain DUF3385 PF11865.8 KZN85389.1 - 0.0078 16.1 5.4 0.83 9.5 0.1 5.1 5 2 0 5 5 5 1 Domain of unknown function (DUF3385) CLASP_N PF12348.8 KZN85389.1 - 0.046 13.3 0.3 1.3 8.6 0.0 2.9 3 0 0 3 3 3 0 CLASP N terminal MMS19_C PF12460.8 KZN85389.1 - 0.11 11.5 0.1 3.9 6.5 0.0 3.3 4 0 0 4 4 4 0 RNAPII transcription regulator C-terminal CTD PF12815.7 KZN85389.1 - 1.2 9.7 5.6 1.3 9.6 3.4 2.2 2 0 0 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 zf-H2C2_2 PF13465.6 KZN85390.1 - 3.7e-10 39.8 14.6 3.7e-05 24.0 0.4 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KZN85390.1 - 1e-09 38.3 11.6 2.2e-05 24.7 4.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KZN85390.1 - 1.1e-06 29.0 10.9 0.0013 19.4 3.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KZN85390.1 - 5.7e-06 26.5 1.3 1.8e-05 25.0 1.3 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KZN85390.1 - 0.00012 22.0 2.4 0.00012 22.0 2.4 2.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KZN85390.1 - 0.00069 19.8 5.1 0.00073 19.8 1.8 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KZN85390.1 - 0.069 13.5 1.1 0.069 13.5 1.1 1.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Actin_micro PF17003.5 KZN85390.1 - 0.22 10.7 0.2 0.3 10.2 0.2 1.1 1 0 0 1 1 1 0 Putative actin-like family zf-C2H2_11 PF16622.5 KZN85390.1 - 0.24 11.2 6.4 4.9 7.0 0.5 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KZN85390.1 - 0.38 10.7 6.6 2.8 7.9 0.4 2.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Spem1 PF15670.5 KZN85391.1 - 0.5 9.9 1.9 0.97 9.0 1.9 1.4 1 0 0 1 1 1 0 Spermatid maturation protein 1 DUF1481 PF07356.12 KZN85391.1 - 0.77 9.5 4.8 4.7 6.9 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1481) ARS2 PF04959.13 KZN85391.1 - 7.7 6.8 15.4 3.2 8.1 4.0 2.6 2 0 0 2 2 2 0 Arsenite-resistance protein 2 Sec1 PF00995.23 KZN85392.1 - 5e-115 385.9 0.0 5.6e-115 385.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Transposase_22 PF02994.14 KZN85392.1 - 0.07 13.3 0.1 0.34 11.1 0.0 2.2 2 0 0 2 2 2 0 L1 transposable element RBD-like domain Telomere_reg-2 PF10193.9 KZN85393.1 - 7.1e-28 97.2 0.0 3.7e-27 94.9 0.0 2.3 2 0 0 2 2 2 1 Telomere length regulation protein HEAT_2 PF13646.6 KZN85393.1 - 3.7 8.0 6.6 21 5.6 0.0 4.6 6 0 0 6 6 6 0 HEAT repeats ThiF PF00899.21 KZN85394.1 - 1.6e-63 214.3 0.0 2.2e-63 213.9 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KZN85394.1 - 4.7e-29 100.4 0.0 8e-29 99.6 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain Cu-oxidase_2 PF07731.14 KZN85394.1 - 0.046 13.5 0.1 0.078 12.7 0.1 1.3 1 0 0 1 1 1 0 Multicopper oxidase Ecm33 PF12454.8 KZN85394.1 - 0.075 13.2 0.3 0.16 12.2 0.3 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein UBA_e1_thiolCys PF10585.9 KZN85394.1 - 0.12 12.2 4.9 0.71 9.7 0.2 2.2 1 1 1 2 2 2 0 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 KZN85394.1 - 0.14 12.9 0.0 0.33 11.7 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin fold domain Shikimate_DH PF01488.20 KZN85394.1 - 0.16 12.0 0.2 2.5 8.1 0.0 2.4 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase RNA_pol_A_bac PF01000.26 KZN85395.1 - 5.7e-28 97.5 0.0 1.1e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KZN85395.1 - 1.4e-19 69.3 0.0 1.9e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_49kDa PF00346.19 KZN85396.1 - 1.6e-123 411.2 0.0 2.2e-123 410.7 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KZN85396.1 - 0.0078 15.2 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Nickel-dependent hydrogenase Mito_carr PF00153.27 KZN85397.1 - 1.6e-43 146.6 0.1 1e-14 54.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3654 PF12376.8 KZN85398.1 - 0.029 14.6 0.0 0.055 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3654) F-box-like PF12937.7 KZN85398.1 - 0.049 13.5 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.7 KZN85399.1 - 0.0081 16.0 0.1 0.02 14.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like SAP PF02037.27 KZN85400.1 - 1.9e-10 40.2 0.4 6.2e-10 38.6 0.0 2.1 2 0 0 2 2 2 1 SAP domain Tho1_MOS11_C PF18592.1 KZN85400.1 - 9.1e-08 31.8 0.4 9.1e-08 31.8 0.4 1.9 2 0 0 2 2 2 1 Tho1/MOS11 C-terminal domain Usp PF00582.26 KZN85400.1 - 1 9.8 5.3 0.36 11.3 0.3 2.2 2 0 0 2 2 2 0 Universal stress protein family Methyltransf_11 PF08241.12 KZN85401.1 - 0.00046 20.8 0.0 0.001 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ATP-synt_DE PF00401.20 KZN85401.1 - 0.0048 17.1 0.4 0.019 15.2 0.5 2.0 2 0 0 2 2 2 1 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Methyltransf_25 PF13649.6 KZN85401.1 - 0.12 13.1 0.0 0.32 11.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.22 KZN85402.1 - 7.9e-74 249.1 0.0 9.4e-74 248.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Annexin PF00191.20 KZN85403.1 - 3.7e-60 199.9 0.5 8.4e-19 67.4 0.0 4.2 4 0 0 4 4 4 4 Annexin RAP1 PF07218.11 KZN85404.1 - 0.17 10.2 0.0 0.18 10.0 0.0 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MFS_1 PF07690.16 KZN85406.1 - 1.4e-13 50.5 43.6 3.3e-12 46.0 41.5 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily HCO3_cotransp PF00955.21 KZN85407.1 - 1.2e-68 232.2 14.5 2.1e-38 132.4 5.4 2.0 1 1 1 2 2 2 2 HCO3- transporter family DUF1955 PF09205.10 KZN85407.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) SET PF00856.28 KZN85408.1 - 7.8e-10 39.4 0.1 1.5e-08 35.2 0.0 2.5 2 1 1 3 3 3 1 SET domain zf-C3HC4 PF00097.25 KZN85409.1 - 2.7e-08 33.5 5.3 2.7e-08 33.5 5.3 4.7 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KZN85409.1 - 7.2e-08 32.3 5.3 7.2e-08 32.3 5.3 3.5 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 KZN85409.1 - 1.9e-06 28.1 6.7 1.9e-06 28.1 6.7 4.5 4 0 0 4 4 4 2 Ring finger domain zf-RING_6 PF14835.6 KZN85409.1 - 3.4e-06 26.8 3.0 3.4e-06 26.8 3.0 2.9 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.6 KZN85409.1 - 3.6e-06 26.7 6.6 3.6e-06 26.7 6.6 4.2 4 3 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KZN85409.1 - 1.6e-05 24.7 5.3 1.6e-05 24.7 5.3 5.5 5 0 0 5 5 5 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KZN85409.1 - 3.7e-05 23.8 6.7 3.7e-05 23.8 6.7 4.0 5 1 0 5 5 5 1 zinc finger of C3HC4-type, RING SH3_9 PF14604.6 KZN85409.1 - 0.00014 21.6 0.1 0.00014 21.6 0.1 2.6 3 0 0 3 3 3 1 Variant SH3 domain SH3_2 PF07653.17 KZN85409.1 - 0.0035 17.0 0.1 0.012 15.3 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KZN85409.1 - 0.0046 16.5 0.1 0.011 15.4 0.1 1.6 1 0 0 1 1 1 1 SH3 domain CBM_21 PF03370.13 KZN85410.1 - 1.5e-36 125.0 0.6 2.4e-36 124.3 0.6 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KZN85410.1 - 3.3e-10 40.4 2.4 7.1e-10 39.3 2.4 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) CENP-T_C PF15511.6 KZN85411.1 - 4.4e-09 36.4 0.1 5.3e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KZN85411.1 - 1.3e-05 25.6 0.2 1.5e-05 25.4 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KZN85411.1 - 4.2e-05 23.6 0.2 6e-05 23.1 0.2 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KZN85411.1 - 6.3e-05 23.2 0.1 0.00011 22.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KZN85411.1 - 0.00016 21.9 0.1 0.00022 21.5 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KZN85411.1 - 0.0037 17.3 0.0 0.0044 17.1 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KZN85411.1 - 0.0063 16.5 0.0 0.0075 16.3 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated UPF0137 PF03677.13 KZN85411.1 - 0.028 14.2 0.2 0.034 14.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) TFIID_20kDa PF03847.13 KZN85411.1 - 0.066 13.7 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A HIGH_NTase1_ass PF16581.5 KZN85411.1 - 0.075 13.0 0.0 0.084 12.9 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region PAD_porph PF04371.15 KZN85412.1 - 8.9e-92 307.8 0.0 1e-91 307.6 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Fungal_trans_2 PF11951.8 KZN85413.1 - 8.3e-06 24.8 0.0 1.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN85413.1 - 2 8.6 5.5 3.6 7.8 5.5 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SR-25 PF10500.9 KZN85413.1 - 2.7 7.6 10.8 4.3 6.9 10.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Acetyltransf_3 PF13302.7 KZN85414.1 - 1.3e-14 55.0 0.0 1.7e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KZN85414.1 - 2.1e-10 40.9 0.1 3.5e-10 40.1 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KZN85414.1 - 0.00055 20.3 0.0 0.00085 19.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KZN85414.1 - 0.0012 18.5 0.0 0.011 15.4 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KZN85414.1 - 0.017 15.2 0.0 0.032 14.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KZN85414.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Mito_carr PF00153.27 KZN85415.1 - 1e-45 153.6 1.0 7.7e-15 54.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF346 PF03984.13 KZN85415.1 - 0.016 14.9 1.0 0.016 14.9 1.0 1.8 2 0 0 2 2 2 0 Repeat of unknown function (DUF346) DUF883 PF05957.13 KZN85415.1 - 0.074 13.7 0.9 0.41 11.3 0.4 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Arm-DNA-bind_3 PF13356.6 KZN85415.1 - 0.12 12.8 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 Arm DNA-binding domain EBP PF05241.12 KZN85416.1 - 1.1e-67 226.9 5.4 1.3e-67 226.7 5.4 1.1 1 0 0 1 1 1 1 Emopamil binding protein SesA PF17107.5 KZN85417.1 - 0.00012 22.3 0.0 0.00026 21.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF3292 PF11696.8 KZN85418.1 - 3.8e-234 778.9 0.0 4.3e-234 778.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) ABM PF03992.16 KZN85419.1 - 0.00019 21.5 0.5 0.00048 20.2 0.0 1.9 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase DUF3239 PF11580.8 KZN85419.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3239) adh_short PF00106.25 KZN85421.1 - 5e-08 32.6 0.0 7e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN85421.1 - 5.3e-06 26.1 0.0 7.3e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Deltaretro_Tax PF05599.11 KZN85421.1 - 0.089 13.3 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Deltaretrovirus Tax protein L31 PF09784.9 KZN85424.1 - 7.3e-46 154.8 1.3 8.1e-46 154.6 1.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Acyltransferase PF01553.21 KZN85425.1 - 9.3e-07 28.5 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DEAD PF00270.29 KZN85427.1 - 7.6e-43 146.3 0.9 1.2e-42 145.6 0.9 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KZN85427.1 - 1.5e-32 112.2 1.3 1e-29 103.1 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 KZN85427.1 - 3e-08 33.9 0.0 7.2e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDC45 PF02724.14 KZN85427.1 - 0.0045 15.4 0.2 0.0063 14.9 0.2 1.2 1 0 0 1 1 1 1 CDC45-like protein RPN2_C PF18004.1 KZN85427.1 - 0.24 11.3 9.1 0.66 9.9 9.1 1.7 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CCDC106 PF15794.5 KZN85427.1 - 1.2 8.8 10.1 0.069 12.9 4.3 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 ABC_tran PF00005.27 KZN85431.1 - 1.2e-27 97.1 0.1 1.9e-27 96.4 0.1 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KZN85431.1 - 6.3e-27 94.4 29.6 1.1e-26 93.6 29.6 1.4 1 0 0 1 1 1 1 ABC-2 type transporter AAA_16 PF13191.6 KZN85431.1 - 1.3e-06 28.9 0.1 2e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KZN85431.1 - 2.6e-06 27.4 0.0 7e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KZN85431.1 - 5.9e-05 22.7 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KZN85431.1 - 0.0001 22.5 0.0 0.00019 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KZN85431.1 - 0.0003 20.7 0.1 0.37 10.6 0.0 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 KZN85431.1 - 0.00051 20.3 0.0 0.001 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 KZN85431.1 - 0.00051 20.0 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain RNA_helicase PF00910.22 KZN85431.1 - 0.00063 20.1 0.0 0.041 14.3 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA PF00004.29 KZN85431.1 - 0.002 18.6 0.1 0.011 16.2 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KZN85431.1 - 0.0021 17.8 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KZN85431.1 - 0.0036 17.9 0.0 0.0082 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KZN85431.1 - 0.0038 17.5 0.1 0.011 16.1 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_30 PF13604.6 KZN85431.1 - 0.0047 16.7 0.0 0.0083 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KZN85431.1 - 0.01 15.8 0.1 0.021 14.7 0.1 1.5 1 0 0 1 1 1 0 NACHT domain CbiA PF01656.23 KZN85431.1 - 0.013 15.6 0.1 0.025 14.6 0.1 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 KZN85431.1 - 0.015 15.4 0.0 0.037 14.1 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_13 PF13166.6 KZN85431.1 - 0.022 13.5 0.0 0.055 12.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KZN85431.1 - 0.022 14.8 0.0 0.074 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 KZN85431.1 - 0.026 14.5 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TsaE PF02367.17 KZN85431.1 - 0.034 14.2 0.0 0.076 13.0 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KZN85431.1 - 0.058 13.0 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 KZN85431.1 - 0.069 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.6 KZN85431.1 - 0.071 13.2 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KZN85431.1 - 0.082 11.9 0.2 0.14 11.1 0.2 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 KZN85431.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 KZN85431.1 - 0.11 12.3 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain FAM86 PF14904.6 KZN85431.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function AAA_35 PF14516.6 KZN85431.1 - 0.14 11.0 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain NB-ARC PF00931.22 KZN85431.1 - 0.15 11.3 0.0 0.35 10.0 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain SRP54 PF00448.22 KZN85431.1 - 0.15 11.7 0.1 0.28 10.8 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 KZN85431.1 - 0.18 12.3 0.0 0.42 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KZN85431.1 - 0.19 11.4 0.0 0.43 10.3 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation tRNA-synt_1d PF00750.19 KZN85432.1 - 3.8e-99 331.9 7.5 3.8e-98 328.6 7.5 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KZN85432.1 - 1e-27 96.6 0.3 2.9e-27 95.2 0.3 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KZN85432.1 - 1.4e-09 38.4 0.8 6.6e-09 36.2 0.0 2.3 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain DUF2203 PF09969.9 KZN85432.1 - 0.35 11.6 2.2 1.7e+02 2.9 0.0 3.3 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) FAD_binding_6 PF00970.24 KZN85433.1 - 4.4e-33 113.6 0.0 6.8e-33 113.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KZN85433.1 - 7.1e-28 97.4 0.0 1.1e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KZN85433.1 - 6.8e-07 29.5 0.0 9.1e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KZN85433.1 - 0.0066 16.6 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DUF3605 PF12239.8 KZN85434.1 - 1.2e-60 204.3 0.0 1.4e-60 204.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Dimerisation2 PF16864.5 KZN85436.1 - 0.0067 16.4 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain Rrf2 PF02082.20 KZN85436.1 - 0.052 13.9 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator Dimerisation PF08100.11 KZN85436.1 - 0.13 12.3 0.2 0.56 10.3 0.1 2.1 2 0 0 2 2 2 0 Dimerisation domain Methyltransf_2 PF00891.18 KZN85437.1 - 4.7e-24 84.9 0.0 7.5e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain SMC_N PF02463.19 KZN85438.1 - 2.5e-73 246.1 0.0 4.1e-73 245.5 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KZN85438.1 - 1.9e-31 108.8 0.0 9.3e-31 106.6 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KZN85438.1 - 6.7e-19 69.2 3.2 6.7e-19 69.2 3.2 6.9 2 2 2 4 4 3 1 AAA domain AAA_21 PF13304.6 KZN85438.1 - 3.9e-16 59.7 11.5 1.6e-10 41.3 0.0 3.5 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KZN85438.1 - 1.1e-13 51.7 45.7 2.4e-08 34.1 17.0 4.6 2 2 1 3 3 3 2 AAA ATPase domain APG6_N PF17675.1 KZN85438.1 - 0.0019 18.7 112.5 0.0039 17.7 11.2 8.4 2 2 4 8 8 8 3 Apg6 coiled-coil region XH PF03469.14 KZN85438.1 - 0.004 17.1 4.6 0.019 14.8 0.6 3.6 2 0 0 2 2 2 1 XH domain AAA_29 PF13555.6 KZN85438.1 - 0.0052 16.5 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Laminin_II PF06009.12 KZN85438.1 - 0.0094 16.0 5.0 0.0094 16.0 5.0 8.4 5 2 6 11 11 11 2 Laminin Domain II FtsK_SpoIIIE PF01580.18 KZN85438.1 - 0.01 15.2 1.5 0.14 11.5 0.0 2.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family FliD_N PF02465.18 KZN85438.1 - 0.013 16.2 2.4 0.013 16.2 2.4 7.6 5 3 2 7 7 6 0 Flagellar hook-associated protein 2 N-terminus DUF87 PF01935.17 KZN85438.1 - 2.9 7.9 0.0 2.9 7.9 0.0 6.2 3 2 4 7 7 6 0 Helicase HerA, central domain Spc7 PF08317.11 KZN85438.1 - 3.3 6.5 101.1 0.02 13.8 18.7 6.7 2 2 5 7 7 7 0 Spc7 kinetochore protein RIO1 PF01163.22 KZN85439.1 - 4.7e-72 241.5 0.1 4.7e-72 241.5 0.1 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KZN85439.1 - 0.0017 18.4 0.0 0.71 9.7 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KZN85439.1 - 0.019 14.3 0.2 0.22 10.9 0.2 2.2 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APG17 PF04108.12 KZN85440.1 - 5.5e-132 440.6 0.6 6.5e-132 440.4 0.6 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 HD_2 PF12917.7 KZN85440.1 - 0.023 14.5 0.2 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 HD containing hydrolase-like enzyme HR1 PF02185.16 KZN85440.1 - 0.027 14.6 1.5 0.2 11.8 0.2 2.6 2 0 0 2 2 2 0 Hr1 repeat AA_synth PF06684.11 KZN85440.1 - 0.13 11.7 0.1 0.27 10.7 0.1 1.4 1 0 0 1 1 1 0 Amino acid synthesis DUF4358 PF14270.6 KZN85440.1 - 0.17 12.2 0.2 0.45 10.8 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) Apt1 PF10351.9 KZN85440.1 - 0.21 10.4 3.8 0.2 10.5 0.1 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Goodbye PF17109.5 KZN85440.1 - 0.24 11.8 0.8 34 4.9 0.1 2.6 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain HAUS-augmin3 PF14932.6 KZN85440.1 - 3.1 7.3 7.6 6.3 6.3 0.2 3.2 2 2 1 3 3 3 0 HAUS augmin-like complex subunit 3 WD40 PF00400.32 KZN85441.1 - 7.4e-42 140.5 14.3 1.9e-06 28.5 0.0 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 KZN85441.1 - 2.1e-13 49.9 0.8 4.6e-13 48.9 0.8 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 KZN85441.1 - 7.1e-11 41.5 5.6 0.049 12.3 0.1 5.3 3 1 2 5 5 5 5 Nucleoporin Nup120/160 F-box PF00646.33 KZN85441.1 - 1.6e-10 40.6 1.1 3.4e-10 39.5 0.1 2.1 2 0 0 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 KZN85441.1 - 0.00033 20.9 0.2 0.93 9.8 0.0 3.9 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 KZN85441.1 - 0.0013 18.6 0.1 0.014 15.2 0.0 2.6 2 0 0 2 2 2 1 F-box THEG4 PF15834.5 KZN85443.1 - 3.2 7.7 8.1 8 6.4 4.7 2.4 2 0 0 2 2 2 0 Testis highly expressed protein 4 UCH PF00443.29 KZN85444.1 - 2.6e-59 200.8 0.0 4e-59 200.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KZN85444.1 - 2.1e-12 47.3 1.3 9.4e-05 22.1 0.1 3.8 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KZN85444.1 - 1.9e-08 34.8 0.0 1.4e-07 32.0 0.0 2.5 3 0 0 3 3 3 1 DUSP domain PX PF00787.24 KZN85446.1 - 1.6e-17 63.5 0.0 6.4e-17 61.6 0.0 2.0 3 0 0 3 3 3 1 PX domain Vps5 PF09325.10 KZN85446.1 - 1.8e-06 27.7 9.8 0.0029 17.2 2.1 2.2 2 0 0 2 2 2 2 Vps5 C terminal like Peptidase_C10 PF01640.17 KZN85446.1 - 0.02 15.2 0.0 0.069 13.5 0.0 1.7 2 0 0 2 2 2 0 Peptidase C10 family Glyco_hydro_43 PF04616.14 KZN85447.1 - 7.1e-41 140.4 0.9 1e-40 139.9 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Pkinase PF00069.25 KZN85448.1 - 6.9e-05 22.3 0.0 0.0004 19.8 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain PA26 PF04636.13 KZN85449.1 - 2.9 6.7 5.8 5.9 5.7 5.8 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF2428 PF10350.9 KZN85450.1 - 1e-63 215.2 0.0 2.1e-63 214.1 0.0 1.6 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 KZN85450.1 - 4.5e-07 29.6 9.5 2 8.9 0.2 6.5 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.6 KZN85450.1 - 0.0022 18.3 2.6 12 6.3 0.0 4.8 4 1 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 KZN85450.1 - 0.011 16.2 5.2 17 6.0 0.1 5.6 5 0 0 5 5 5 0 HEAT-like repeat Arm PF00514.23 KZN85450.1 - 0.027 14.5 0.1 1.1 9.5 0.1 3.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Condensin2nSMC PF12422.8 KZN85450.1 - 0.071 13.3 0.1 1 9.5 0.0 2.7 3 0 0 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit Tim17 PF02466.19 KZN85452.1 - 1e-26 93.5 3.7 1.3e-26 93.1 3.7 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Fungal_trans_2 PF11951.8 KZN85453.1 - 1.9e-35 122.4 4.8 3e-35 121.8 4.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.25 KZN85454.1 - 1.2e-43 149.4 0.0 3.4e-42 144.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN85454.1 - 8.4e-26 90.8 0.0 1.4e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KZN85454.1 - 0.00082 18.2 0.0 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KZN85454.1 - 0.0013 18.1 0.0 0.0037 16.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Lipase_3 PF01764.25 KZN85455.1 - 1.8e-19 70.0 0.0 3.3e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) FAD_binding_4 PF01565.23 KZN85456.1 - 4.4e-27 94.5 1.3 7.1e-27 93.8 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KZN85456.1 - 1.1e-13 51.1 0.0 2.6e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.16 KZN85458.1 - 1.2e-14 54.0 22.3 1.2e-14 54.0 22.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KZN85458.1 - 0.0019 16.5 0.0 0.0019 16.5 0.0 1.5 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF202 PF02656.15 KZN85458.1 - 0.14 12.6 0.0 0.14 12.6 0.0 4.4 3 2 0 3 3 3 0 Domain of unknown function (DUF202) RAI16-like PF10257.9 KZN85459.1 - 7.8e-86 288.2 0.0 1.1e-85 287.6 0.0 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Retinal PF15449.6 KZN85459.1 - 3.8 5.2 14.4 5.6 4.6 14.4 1.1 1 0 0 1 1 1 0 Retinal protein CBFD_NFYB_HMF PF00808.23 KZN85460.1 - 5.6e-16 58.6 2.1 9.3e-16 57.9 2.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KZN85460.1 - 1.3e-05 25.5 0.8 2.7e-05 24.6 0.8 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 zf-C3HC4_3 PF13920.6 KZN85461.1 - 0.00051 19.8 12.1 0.0009 19.1 12.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 KZN85461.1 - 0.13 12.4 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 U-box domain DUF1899 PF08953.11 KZN85462.1 - 2.2e-33 113.9 0.0 4.8e-33 112.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KZN85462.1 - 4.4e-21 74.5 0.1 9.9e-21 73.4 0.1 1.6 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KZN85462.1 - 1.2e-17 63.9 4.4 0.00033 21.4 0.2 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN85462.1 - 2.3e-06 27.8 0.0 0.032 14.5 0.0 3.3 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KZN85462.1 - 0.00061 18.6 0.2 0.24 10.0 0.2 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DivIC PF04977.15 KZN85462.1 - 0.037 13.8 0.8 0.077 12.8 0.8 1.4 1 0 0 1 1 1 0 Septum formation initiator SlyX PF04102.12 KZN85462.1 - 0.069 13.8 2.4 0.12 13.0 1.3 1.9 2 0 0 2 2 2 0 SlyX SPX PF03105.19 KZN85462.1 - 1.4 8.8 5.6 1.9 8.3 5.6 1.1 1 0 0 1 1 1 0 SPX domain Kinesin PF00225.23 KZN85463.1 - 3.1e-105 351.8 0.8 3.1e-105 351.8 0.8 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KZN85463.1 - 5.4e-60 201.7 0.1 1.7e-59 200.0 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding AAA_16 PF13191.6 KZN85463.1 - 0.012 16.0 0.0 0.012 16.0 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain ATPase_2 PF01637.18 KZN85463.1 - 0.019 14.9 2.7 0.98 9.3 0.0 2.6 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 KZN85463.1 - 0.034 14.0 0.4 0.093 12.6 0.0 1.9 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_22 PF13401.6 KZN85463.1 - 0.052 13.8 2.4 0.47 10.7 0.0 3.0 2 1 1 3 3 3 0 AAA domain IF-2B PF01008.17 KZN85464.1 - 8.2e-19 67.9 0.0 1.6e-18 67.0 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.28 KZN85464.1 - 1.5e-14 54.2 0.1 2.9e-14 53.2 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain CAAX_1 PF15895.5 KZN85464.1 - 0.00053 20.0 0.1 0.00084 19.3 0.1 1.2 1 0 0 1 1 1 1 CAAX box cerebral protein 1 DUF3631 PF12307.8 KZN85464.1 - 0.0072 16.6 0.2 0.017 15.4 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3631) GFA PF04828.14 KZN85465.1 - 3.1e-19 69.1 0.2 4.3e-19 68.7 0.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme RecR PF02132.15 KZN85465.1 - 9.5 5.9 12.1 0.72 9.5 1.8 2.9 3 0 0 3 3 3 0 RecR protein PRK PF00485.18 KZN85466.1 - 9.1e-08 32.1 0.0 1.8e-06 27.8 0.0 2.1 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KZN85466.1 - 2.1e-06 28.3 0.0 3.7e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KZN85466.1 - 0.00012 22.5 0.0 0.00025 21.5 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KZN85466.1 - 0.00016 21.8 0.0 0.0011 19.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KZN85466.1 - 0.00041 20.0 0.0 0.00067 19.3 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA PF00004.29 KZN85466.1 - 0.00065 20.1 0.0 0.001 19.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KZN85466.1 - 0.001 18.4 0.0 0.003 16.8 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 KZN85466.1 - 0.0012 19.1 0.0 0.0026 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KZN85466.1 - 0.0012 19.3 0.0 0.011 16.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 KZN85466.1 - 0.003 17.2 0.0 0.2 11.3 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase KTI12 PF08433.10 KZN85466.1 - 0.0049 16.4 0.0 0.007 15.9 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 MeaB PF03308.16 KZN85466.1 - 0.0062 15.6 0.0 0.009 15.0 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KZN85466.1 - 0.0085 15.8 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KZN85466.1 - 0.012 14.7 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 KZN85466.1 - 0.022 14.7 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 KZN85466.1 - 0.023 15.0 0.0 0.036 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KZN85466.1 - 0.037 13.2 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 KZN85466.1 - 0.054 12.7 0.0 0.066 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.20 KZN85466.1 - 0.054 13.4 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase NTPase_1 PF03266.15 KZN85466.1 - 0.062 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 NTPase ResIII PF04851.15 KZN85466.1 - 0.072 13.1 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MobB PF03205.14 KZN85466.1 - 0.1 12.5 0.0 0.34 10.8 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_11 PF13086.6 KZN85466.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain POTRA_1 PF08478.10 KZN85466.1 - 0.14 12.5 0.0 11 6.4 0.0 2.7 3 0 0 3 3 2 0 POTRA domain, FtsQ-type AAA_24 PF13479.6 KZN85466.1 - 0.2 11.4 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KZN85466.1 - 0.22 11.3 0.1 0.72 9.6 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Hemerythrin PF01814.23 KZN85467.1 - 3.1e-11 44.0 1.9 3.1e-11 44.0 1.9 1.9 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain RTA1 PF04479.13 KZN85468.1 - 1.3e-76 256.8 11.9 1.8e-76 256.4 11.9 1.1 1 0 0 1 1 1 1 RTA1 like protein LHC PF00556.20 KZN85468.1 - 0.85 9.9 4.5 19 5.6 0.9 2.8 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit Na_Ca_ex PF01699.24 KZN85469.1 - 1.7e-43 148.2 38.5 2e-23 83.0 16.6 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Fungal_trans PF04082.18 KZN85470.1 - 4.4e-20 71.8 0.0 6.7e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN85470.1 - 6.3e-05 23.0 7.6 0.00011 22.2 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytochrom_B_C PF00032.17 KZN85471.1 - 0.016 15.5 3.3 0.035 14.4 0.1 2.5 1 1 1 2 2 2 0 Cytochrome b(C-terminal)/b6/petD SUR7 PF06687.12 KZN85471.1 - 0.017 14.8 0.9 0.017 14.8 0.9 2.3 2 1 0 2 2 2 0 SUR7/PalI family DUF2614 PF11023.8 KZN85471.1 - 0.037 14.1 1.9 0.037 14.1 1.9 2.0 2 0 0 2 2 2 0 Zinc-ribbon containing domain LptF_LptG PF03739.14 KZN85471.1 - 0.13 11.1 14.4 0.027 13.3 5.2 2.3 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG Acyl_transf_3 PF01757.22 KZN85471.1 - 1.1 8.2 16.8 9.4 5.2 16.8 2.0 1 1 0 1 1 1 0 Acyltransferase family TM_helix PF05552.12 KZN85471.1 - 1.4 8.9 7.8 0.14 12.1 1.6 2.7 2 0 0 2 2 2 0 Conserved TM helix PHD PF00628.29 KZN85472.1 - 7.9e-05 22.5 5.5 0.00015 21.6 5.5 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KZN85472.1 - 0.00047 19.7 1.8 0.00086 18.8 1.8 1.5 1 0 0 1 1 1 1 PHD-finger AA_permease PF00324.21 KZN85474.1 - 2.5e-133 445.2 45.6 3e-133 444.9 45.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KZN85474.1 - 1e-33 116.8 52.5 1.2e-33 116.6 52.5 1.0 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 KZN85475.1 - 7.7e-22 77.7 32.2 7.7e-22 77.7 32.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN85475.1 - 1.8e-06 27.1 9.8 1.8e-06 27.1 9.8 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN85476.1 - 4.9e-40 137.5 36.8 4.9e-40 137.5 36.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN85476.1 - 8.6e-14 51.2 36.8 7.9e-13 48.1 12.7 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter OATP PF03137.20 KZN85476.1 - 0.046 12.0 7.3 0.0056 15.0 2.5 1.9 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.18 KZN85477.1 - 1e-16 60.8 2.1 1.8e-16 60.0 2.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KZN85478.1 - 5.6e-07 28.8 0.4 2.7e-06 26.6 0.2 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN85479.1 - 2.9e-08 33.7 13.6 4.5e-08 33.1 13.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IML1 PF12257.8 KZN85480.1 - 1e-112 375.9 0.0 1.5e-112 375.4 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 KZN85480.1 - 9.9e-28 96.0 0.7 1.9e-27 95.1 0.7 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Methyltransf_31 PF13847.6 KZN85481.1 - 2.8e-11 43.4 0.0 3.7e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN85481.1 - 7.7e-11 42.6 0.0 1.4e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN85481.1 - 1e-10 42.1 0.0 2.5e-10 40.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN85481.1 - 1.6e-08 34.6 0.0 2.4e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN85481.1 - 3.6e-08 34.1 0.0 5.3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KZN85481.1 - 0.0057 16.0 0.1 0.011 15.0 0.1 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KZN85481.1 - 0.0064 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase adh_short_C2 PF13561.6 KZN85481.1 - 0.0079 15.8 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MTS PF05175.14 KZN85481.1 - 0.027 14.0 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain adh_short PF00106.25 KZN85481.1 - 0.031 13.7 0.0 0.045 13.2 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Methyltransf_18 PF12847.7 KZN85481.1 - 0.038 13.9 0.0 0.06 13.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_31 PF01055.26 KZN85482.1 - 1.8e-113 380.0 1.5 2.3e-113 379.7 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KZN85482.1 - 7.3e-19 67.9 0.0 4.7e-18 65.3 0.1 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like FNIP_N PF14636.6 KZN85483.1 - 2.3e-28 100.1 0.0 2.3e-28 100.1 0.0 4.0 2 1 0 2 2 2 1 Folliculin-interacting protein N-terminus NUC153 PF08159.12 KZN85484.1 - 1.4e-14 53.6 8.5 1.1e-12 47.6 0.8 3.9 3 0 0 3 3 3 3 NUC153 domain PRK PF00485.18 KZN85485.1 - 9.4e-58 195.2 0.0 1.4e-57 194.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 KZN85485.1 - 7.4e-41 139.9 0.0 1.3e-40 139.0 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 KZN85485.1 - 7.2e-07 29.8 0.1 1.5e-05 25.5 0.0 2.5 3 0 0 3 3 3 1 AAA domain CPT PF07931.12 KZN85485.1 - 6.8e-05 22.8 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Cytidylate_kin PF02224.18 KZN85485.1 - 0.0013 18.5 0.1 0.073 12.8 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase AAA_33 PF13671.6 KZN85485.1 - 0.0034 17.5 0.0 0.0068 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KZN85485.1 - 0.0042 17.5 0.0 4.4 7.7 0.0 3.0 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.17 KZN85485.1 - 0.035 14.2 0.0 0.072 13.2 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain Pribosyltran PF00156.27 KZN85485.1 - 0.037 13.6 0.0 0.083 12.4 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosyl transferase domain APS_kinase PF01583.20 KZN85485.1 - 0.043 13.7 0.5 0.7 9.8 0.0 2.7 3 0 0 3 3 3 0 Adenylylsulphate kinase Zeta_toxin PF06414.12 KZN85485.1 - 0.048 12.9 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 KZN85485.1 - 0.1 12.9 0.0 0.32 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 KZN85485.1 - 0.16 12.5 0.3 0.55 10.8 0.1 1.9 2 0 0 2 2 2 0 ABC transporter NB-ARC PF00931.22 KZN85485.1 - 0.17 11.0 0.1 0.51 9.5 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain CLTH PF10607.9 KZN85486.1 - 2.8e-32 111.6 0.0 3.7e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KZN85486.1 - 1.5e-09 37.5 0.0 2.8e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 LisH Pyr_redox_2 PF07992.14 KZN85488.1 - 9.5e-46 156.3 0.0 1.3e-45 155.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KZN85488.1 - 6.8e-14 52.2 0.0 1.4e-11 44.8 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.6 KZN85488.1 - 1.1e-05 25.7 0.0 2.6e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KZN85488.1 - 2e-05 23.8 0.1 6e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KZN85488.1 - 0.00016 21.3 0.1 0.00052 19.7 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KZN85488.1 - 0.0006 19.2 0.1 0.0055 16.1 0.0 2.3 2 0 0 2 2 2 1 EF hand VEGFR-2_TMD PF17988.1 KZN85488.1 - 7.7 6.0 6.2 33 4.0 0.0 2.6 2 0 0 2 2 2 0 VEGFR-2 Transmembrane domain Nipped-B_C PF12830.7 KZN85489.1 - 5.6e-47 160.1 2.2 3.4e-45 154.3 0.8 2.9 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KZN85489.1 - 8.5e-13 48.3 0.3 3.6e-12 46.4 0.3 2.2 1 0 0 1 1 1 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 KZN85489.1 - 8.3e-05 22.7 2.0 0.0055 16.8 0.0 3.7 2 2 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 KZN85489.1 - 0.00021 20.6 2.5 0.2 10.8 0.0 4.5 5 0 0 5 5 5 2 Nuclear condensing complex subunits, C-term domain Sec7_N PF12783.7 KZN85489.1 - 0.00044 20.2 0.4 0.084 12.8 0.0 4.2 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal MA3 PF02847.17 KZN85489.1 - 0.0053 16.7 0.1 3.9 7.5 0.0 3.6 3 0 0 3 3 3 1 MA3 domain HEAT PF02985.22 KZN85489.1 - 0.0088 16.2 2.3 2 8.9 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat CLAMP PF14769.6 KZN85489.1 - 0.1 13.0 0.1 0.36 11.3 0.1 1.9 1 0 0 1 1 1 0 Flagellar C1a complex subunit C1a-32 TFIIS_C PF01096.18 KZN85490.1 - 2.3e-12 46.6 3.3 2.3e-12 46.6 3.3 3.3 4 0 0 4 4 4 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KZN85490.1 - 1.4e-05 24.9 0.5 1.4e-05 24.9 0.5 2.5 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit DZR PF12773.7 KZN85490.1 - 0.001 19.0 3.7 0.086 12.9 0.5 2.4 2 1 0 2 2 2 2 Double zinc ribbon Zn_ribbon_recom PF13408.6 KZN85490.1 - 0.0014 19.1 3.1 0.16 12.5 0.0 2.3 2 0 0 2 2 2 2 Recombinase zinc beta ribbon domain zf-ribbon_3 PF13248.6 KZN85490.1 - 0.0075 15.6 3.1 12 5.4 0.0 3.5 3 0 0 3 3 3 1 zinc-ribbon domain zf-IS66 PF13005.7 KZN85490.1 - 0.021 15.2 3.1 27 5.3 0.1 3.4 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 C1_1 PF00130.22 KZN85490.1 - 0.037 13.9 3.0 0.088 12.7 0.2 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) A2L_zn_ribbon PF08792.10 KZN85490.1 - 0.082 12.6 4.1 14 5.6 0.0 3.4 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-trcl PF13451.6 KZN85490.1 - 0.12 12.3 4.9 1.8 8.5 0.1 3.2 3 0 0 3 3 3 0 Probable zinc-ribbon domain zinc_ribbon_2 PF13240.6 KZN85490.1 - 0.17 11.6 10.4 2.1 8.1 0.1 3.5 4 0 0 4 4 4 0 zinc-ribbon domain Nudix_N_2 PF14803.6 KZN85490.1 - 0.23 11.4 9.3 7 6.7 0.1 3.5 3 1 0 3 3 3 0 Nudix N-terminal YhfH PF14149.6 KZN85490.1 - 0.59 10.2 5.2 18 5.4 0.1 3.2 3 0 0 3 3 3 0 YhfH-like protein zf-RING_7 PF02591.15 KZN85490.1 - 0.87 9.8 5.6 20 5.5 0.1 3.6 2 1 1 3 3 3 0 C4-type zinc ribbon domain HEAT_2 PF13646.6 KZN85491.1 - 2.1e-27 95.3 0.6 8.1e-12 45.4 0.0 3.8 2 2 3 5 5 5 3 HEAT repeats HEAT_PBS PF03130.16 KZN85491.1 - 2.4e-16 58.7 0.1 0.015 15.9 0.1 6.5 8 0 0 8 8 8 4 PBS lyase HEAT-like repeat HEAT PF02985.22 KZN85491.1 - 6.1e-10 38.5 1.2 1.2 9.6 0.0 5.6 7 0 0 7 7 7 3 HEAT repeat Cnd1 PF12717.7 KZN85491.1 - 0.00063 19.8 0.0 0.15 12.1 0.0 2.8 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 RuvA_C PF07499.13 KZN85491.1 - 0.032 14.7 2.4 6.5 7.3 0.2 3.2 3 0 0 3 3 3 0 RuvA, C-terminal domain Cohesin_HEAT PF12765.7 KZN85491.1 - 0.037 14.3 0.0 0.73 10.2 0.0 2.5 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.6 KZN85491.1 - 0.073 13.6 9.9 18 6.0 0.0 5.3 5 2 2 7 7 7 0 HEAT-like repeat ETC_C1_NDUFA4 PF04800.12 KZN85492.1 - 4.6e-37 126.2 1.5 6.4e-37 125.7 1.5 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF2188 PF09954.9 KZN85492.1 - 0.056 13.6 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) F1F0-ATPsyn_F PF10791.9 KZN85493.1 - 8.4e-36 122.3 0.6 2.2e-32 111.4 0.1 2.0 1 1 1 2 2 2 2 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 KZN85493.1 - 0.018 15.4 0.0 0.03 14.7 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f MOZ_SAS PF01853.18 KZN85495.1 - 1.4e-79 266.0 0.0 1.9e-79 265.5 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.8 KZN85495.1 - 2.6e-23 81.6 0.0 5.6e-23 80.6 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-MYST PF17772.1 KZN85495.1 - 2.7e-21 74.9 0.1 6e-21 73.8 0.1 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 KZN85495.1 - 0.0045 17.4 0.0 0.009 16.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KZN85495.1 - 0.039 14.2 0.0 0.096 12.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family mRNA_cap_enzyme PF01331.19 KZN85496.1 - 4e-54 183.4 0.1 5.7e-54 182.9 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KZN85496.1 - 4.2e-34 117.4 0.0 7.1e-34 116.7 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 KZN85496.1 - 5.3e-08 32.7 0.1 5e-06 26.3 0.0 2.4 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 KZN85496.1 - 0.0006 20.2 0.1 0.023 15.0 0.0 2.2 2 0 0 2 2 2 1 RNA ligase SCA7 PF08313.12 KZN85497.1 - 7.8e-31 105.8 2.6 3.4e-30 103.7 2.6 2.2 1 0 0 1 1 1 1 SCA7, zinc-binding domain CDC45 PF02724.14 KZN85497.1 - 0.74 8.0 12.6 1.1 7.4 12.6 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 KZN85497.1 - 9.5 5.1 5.8 19 4.1 5.8 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) ketoacyl-synt PF00109.26 KZN85498.1 - 9.3e-45 153.2 3.7 1.2e-44 152.8 0.5 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KZN85498.1 - 9.9e-34 115.9 3.6 3.9e-33 114.0 2.9 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KZN85498.1 - 1.8e-05 24.2 3.0 0.00014 21.4 0.4 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KZN85498.1 - 0.0014 18.2 3.2 0.026 14.2 0.5 2.8 3 0 0 3 3 3 1 Thiolase, C-terminal domain Arginase PF00491.21 KZN85499.1 - 3.3e-93 312.2 0.0 4.3e-93 311.9 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KZN85499.1 - 0.00058 20.1 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 UPF0489 domain Ras PF00071.22 KZN85500.1 - 2.5e-52 176.8 0.0 2.9e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KZN85500.1 - 7.1e-19 68.2 0.0 9.5e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KZN85500.1 - 7.3e-06 25.5 0.0 1e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MFS_1 PF07690.16 KZN85501.1 - 1.4e-19 70.3 43.3 8.8e-19 67.6 41.6 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KZN85501.1 - 9.6e-08 30.9 14.4 1.3e-07 30.5 14.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1349 PF07081.11 KZN85502.1 - 2.8e-27 95.6 0.0 3.5e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) CAP59_mtransfer PF11735.8 KZN85503.1 - 2.2e-76 256.7 0.0 2.8e-76 256.4 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 p450 PF00067.22 KZN85504.1 - 5.6e-58 196.8 0.0 1.2e-57 195.7 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Iwr1 PF08574.10 KZN85507.1 - 4.2e-22 78.9 9.1 4.2e-22 78.9 9.1 2.7 3 1 0 3 3 3 1 Transcription factor Iwr1 RRM_1 PF00076.22 KZN85508.1 - 9.3e-38 127.9 0.0 1.6e-11 43.9 0.1 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KZN85508.1 - 1.2e-13 50.7 0.0 0.0011 18.7 0.0 4.3 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM PF10378.9 KZN85508.1 - 2.2e-08 33.7 0.7 2.2e-08 33.7 0.7 2.6 2 0 0 2 2 2 1 Putative RRM domain RRM_3 PF08777.11 KZN85508.1 - 9e-05 22.5 0.1 0.38 10.8 0.0 3.1 3 0 0 3 3 3 2 RNA binding motif DUF4523 PF15023.6 KZN85508.1 - 0.00026 20.9 0.0 0.48 10.2 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_Rrp7 PF17799.1 KZN85508.1 - 0.0014 18.4 0.0 1.4 8.7 0.0 4.0 2 1 2 4 4 4 1 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 KZN85508.1 - 0.0027 17.8 0.0 4 7.6 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif tRNA-synt_2 PF00152.20 KZN85509.1 - 1.7e-87 293.5 0.0 2.6e-87 292.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KZN85509.1 - 9.3e-08 31.9 0.0 1.7e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain MM_CoA_mutase PF01642.22 KZN85510.1 - 0.019 13.5 0.1 0.021 13.4 0.1 1.0 1 0 0 1 1 1 0 Methylmalonyl-CoA mutase BAR_3 PF16746.5 KZN85510.1 - 0.091 12.4 0.1 0.12 12.0 0.1 1.1 1 0 0 1 1 1 0 BAR domain of APPL family Rib_recp_KP_reg PF05104.12 KZN85511.1 - 0.049 14.7 2.2 0.078 14.0 2.2 1.3 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Ecl1 PF12855.7 KZN85512.1 - 5.3e-49 167.7 17.9 5.3e-49 167.7 17.9 2.3 2 0 0 2 2 2 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 KZN85512.1 - 0.037 14.1 1.8 0.085 13.0 1.8 1.5 1 0 0 1 1 1 0 MYND finger zf-FLZ PF04570.14 KZN85512.1 - 0.16 11.4 4.4 0.54 9.8 4.4 1.8 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 YL1 PF05764.13 KZN85513.1 - 7.3e-58 196.6 26.3 7.3e-58 196.6 26.3 2.5 2 1 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 KZN85513.1 - 1.5e-11 43.8 0.4 1.5e-11 43.8 0.4 1.9 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain PUF PF00806.19 KZN85514.1 - 6.3e-29 98.0 0.0 6.2e-05 22.5 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 KZN85514.1 - 3.8e-10 39.4 0.0 8.2e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.16 KZN85515.1 - 3.3e-40 138.1 50.1 1.3e-39 136.2 48.0 2.2 2 1 0 2 2 2 2 Major Facilitator Superfamily Peptidase_C12 PF01088.21 KZN85516.1 - 3.1e-53 180.7 0.0 3.6e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DcpS PF05652.12 KZN85518.1 - 2.1e-34 118.5 0.1 3.3e-34 117.8 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 KZN85518.1 - 1.4e-28 99.7 0.0 2.5e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding RNase_H2_suC PF08615.11 KZN85519.1 - 1.1e-30 106.6 0.0 1.4e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) RNase_T PF00929.24 KZN85520.1 - 5.4e-20 72.6 0.0 2e-19 70.7 0.0 1.9 1 1 0 1 1 1 1 Exonuclease ATPgrasp_YheCD PF14398.6 KZN85520.1 - 0.038 13.2 0.9 0.067 12.4 0.9 1.3 1 0 0 1 1 1 0 YheC/D like ATP-grasp Nop53 PF07767.11 KZN85521.1 - 8.6e-106 354.7 31.6 1.1e-105 354.3 31.6 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Myb_Cef PF11831.8 KZN85522.1 - 9.3e-58 195.6 3.7 9.3e-58 195.6 3.7 3.4 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KZN85522.1 - 1.7e-22 79.3 4.0 6.5e-11 42.2 0.6 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KZN85522.1 - 1.3e-20 73.4 3.2 1.2e-13 51.1 0.7 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 KZN85522.1 - 0.024 14.7 0.3 0.27 11.4 0.0 2.7 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Ribophorin_I PF04597.14 KZN85523.1 - 2e-149 498.5 0.3 2.3e-149 498.4 0.3 1.0 1 0 0 1 1 1 1 Ribophorin I Indigoidine_A PF04227.12 KZN85524.1 - 2.4e-116 388.2 0.2 3.4e-116 387.7 0.2 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 KZN85524.1 - 1.7e-15 57.1 0.2 4.4e-10 39.3 0.0 2.5 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Arrestin_N PF00339.29 KZN85525.1 - 1.6e-06 28.2 0.0 2.9e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain SnoaL PF07366.12 KZN85526.1 - 0.0018 18.0 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase RGS-like PF09128.11 KZN85526.1 - 0.58 9.8 1.5 1.2 8.8 1.5 1.4 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Flavokinase PF01687.17 KZN85527.1 - 2e-32 111.8 0.0 2.7e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Zn_clus PF00172.18 KZN85528.1 - 0.0083 16.2 9.2 0.017 15.2 9.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 KZN85528.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 PAS fold MFS_1 PF07690.16 KZN85529.1 - 7.5e-39 133.6 30.5 9.2e-39 133.4 30.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN85529.1 - 1.9e-09 36.9 9.0 2.2e-09 36.7 7.3 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KZN85529.1 - 5.9e-06 25.0 2.5 5.9e-06 25.0 2.5 2.1 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KZN85529.1 - 0.0029 16.1 1.4 0.0043 15.5 1.4 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector Bap31 PF05529.12 KZN85529.1 - 0.009 15.9 0.0 0.033 14.0 0.0 2.0 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Rad21_Rec8_N PF04825.13 KZN85530.1 - 1.9e-37 127.8 0.1 3.5e-37 126.9 0.1 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KZN85530.1 - 8e-08 31.4 0.4 2.1e-07 30.1 0.4 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein E1-E2_ATPase PF00122.20 KZN85531.1 - 2.4e-47 160.8 0.3 7.6e-47 159.2 0.3 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KZN85531.1 - 2.5e-43 147.9 0.2 2.5e-43 147.9 0.2 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KZN85531.1 - 4.8e-21 76.0 0.3 3.2e-20 73.3 0.3 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KZN85531.1 - 7.6e-19 67.2 0.0 1.5e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KZN85531.1 - 1.3e-14 54.0 0.0 2.7e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KZN85531.1 - 6.7e-05 22.7 2.3 0.00029 20.7 1.1 2.2 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 KZN85532.1 - 2.4e-18 66.4 0.0 1.2e-17 64.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN85532.1 - 1.5e-13 50.7 0.0 5.1e-13 48.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KZN85532.1 - 0.00024 20.5 0.1 0.00038 19.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KZN85532.1 - 0.17 11.4 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Glyco_hydro_79C PF16862.5 KZN85533.1 - 3e-14 53.8 0.0 6.3e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Ammonium_transp PF00909.21 KZN85534.1 - 4.3e-115 384.6 29.1 4.9e-115 384.4 29.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family COG4 PF08318.12 KZN85535.1 - 3.7e-125 417.5 0.0 5.5e-125 416.9 0.0 1.3 1 0 0 1 1 1 1 COG4 transport protein DUF4893 PF16233.5 KZN85535.1 - 0.044 13.4 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4893) SIR2 PF02146.17 KZN85536.1 - 7.6e-58 195.3 0.0 1.1e-57 194.8 0.0 1.3 1 0 0 1 1 1 1 Sir2 family Pup PF05639.11 KZN85536.1 - 0.032 15.1 0.8 0.075 13.9 0.8 1.6 1 0 0 1 1 1 0 Pup-like protein Hexokinase_2 PF03727.16 KZN85537.1 - 1.6e-81 273.3 0.0 2.3e-81 272.7 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KZN85537.1 - 2.6e-73 246.2 0.0 3.5e-73 245.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase FGGY_N PF00370.21 KZN85537.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain PLCC PF14466.6 KZN85537.1 - 0.15 12.2 0.0 4.1 7.5 0.0 2.6 2 1 1 3 3 3 0 PLAT/LH2 and C2-like Ca2+-binding lipoprotein PHO4 PF01384.20 KZN85540.1 - 1.7e-110 369.2 14.2 2e-110 369.0 14.2 1.0 1 0 0 1 1 1 1 Phosphate transporter family DUF2070 PF09843.9 KZN85540.1 - 8.3 4.6 11.7 13 4.0 11.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF1929 PF09118.11 KZN85541.1 - 2.3e-16 59.9 0.0 5e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 KZN85541.1 - 1.5e-14 53.7 4.9 2.9e-06 27.2 0.0 4.5 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.25 KZN85541.1 - 3.9e-10 39.2 1.6 1.1e-05 24.9 0.1 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 KZN85541.1 - 2.9e-08 33.4 4.3 0.045 13.7 0.2 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 KZN85541.1 - 4.7e-06 26.7 5.2 1.3 9.4 0.2 5.0 5 0 0 5 5 5 3 Kelch motif Glyoxal_oxid_N PF07250.11 KZN85541.1 - 0.00024 20.4 0.2 0.13 11.4 0.1 2.7 3 0 0 3 3 3 2 Glyoxal oxidase N-terminus DUF5122 PF17164.4 KZN85541.1 - 1 9.7 5.0 15 6.0 0.1 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller Cu-oxidase_3 PF07732.15 KZN85542.1 - 1.4e-39 134.8 0.4 4.9e-39 133.0 0.3 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KZN85542.1 - 6e-27 94.1 1.8 5.8e-23 81.1 0.0 3.4 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KZN85542.1 - 6.9e-19 68.5 0.0 5.4e-17 62.4 0.0 2.4 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KZN85543.1 - 2.5e-37 127.7 0.6 2.5e-37 127.7 0.6 3.6 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 KZN85543.1 - 4.2e-37 127.7 0.9 1.5e-34 119.4 0.2 2.7 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KZN85543.1 - 8.9e-37 125.7 4.3 8.9e-37 125.7 4.3 2.2 2 0 0 2 2 2 1 Multicopper oxidase JHD PF17811.1 KZN85546.1 - 8.7e-11 42.3 0.4 2.3e-10 40.9 0.4 1.7 1 0 0 1 1 1 1 Jumonji helical domain JmjC PF02373.22 KZN85546.1 - 7.2e-09 36.1 0.1 8.2e-08 32.7 0.1 2.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 KZN85546.1 - 9.5e-09 35.0 6.0 9.5e-09 35.0 6.0 2.7 3 0 0 3 3 3 1 PHD-finger Cupin_8 PF13621.6 KZN85546.1 - 1.4e-08 34.7 0.0 3.3e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Cupin-like domain PHD_2 PF13831.6 KZN85546.1 - 0.00032 20.2 4.5 0.00034 20.1 2.5 2.3 2 0 0 2 2 2 1 PHD-finger Dickkopf_N PF04706.12 KZN85546.1 - 0.74 10.4 8.6 11 6.6 0.5 2.8 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region zf-HC5HC2H PF13771.6 KZN85546.1 - 1.7 8.9 5.8 0.62 10.4 1.4 2.5 2 0 0 2 2 2 0 PHD-like zinc-binding domain Zn_clus PF00172.18 KZN85546.1 - 3 8.0 30.5 0.32 11.2 6.3 3.5 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.22 KZN85547.1 - 1.7e-19 69.4 0.3 2.7e-19 68.7 0.3 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KZN85547.1 - 8.4e-07 28.6 0.0 1e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KZN85547.1 - 0.00083 19.2 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_8 PF11835.8 KZN85547.1 - 0.032 14.4 0.0 0.039 14.2 0.0 1.2 1 0 0 1 1 1 0 RRM-like domain STIMATE PF12400.8 KZN85548.1 - 5.9e-40 136.7 4.6 5.9e-40 136.7 4.6 1.7 2 0 0 2 2 2 1 STIMATE family WD40 PF00400.32 KZN85549.1 - 2.6e-05 24.9 1.4 0.43 11.5 0.0 5.2 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN85549.1 - 6e-05 23.3 0.1 14 6.0 0.0 4.7 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Vps62 PF06101.11 KZN85550.1 - 2.3e-11 42.7 1.0 2.3e-11 42.7 1.0 2.4 3 0 0 3 3 3 1 Vacuolar protein sorting-associated protein 62 TFIIIC_sub6 PF10419.9 KZN85551.1 - 3.1e-22 78.2 0.0 5.9e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain ELFV_dehydrog PF00208.21 KZN85553.1 - 6.9e-65 219.2 0.0 1e-64 218.6 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KZN85553.1 - 2e-16 58.8 0.0 1.4e-11 42.7 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 KZN85553.1 - 0.03 14.2 0.0 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Sporozoite_P67 PF05642.11 KZN85554.1 - 0.006 14.7 7.5 0.0084 14.3 7.5 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Corona_nucleoca PF00937.18 KZN85554.1 - 0.11 11.5 1.5 0.16 11.0 1.5 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein LOR PF04525.12 KZN85554.1 - 0.16 11.6 0.0 1.2 8.7 0.0 2.0 2 0 0 2 2 2 0 LURP-one-related DUF515 PF04415.12 KZN85554.1 - 1.7 6.9 3.4 2.3 6.5 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) ThrE PF06738.12 KZN85555.1 - 3.3e-71 239.5 14.9 1.8e-63 214.1 4.2 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KZN85555.1 - 4.2e-12 46.3 8.9 4.2e-12 46.3 8.9 2.5 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE DUF2934 PF11154.8 KZN85555.1 - 0.22 11.3 0.4 0.43 10.3 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2934) Tom5 PF10642.9 KZN85555.1 - 2.4 8.2 3.8 2.2 8.4 0.0 2.7 3 0 0 3 3 3 0 Mitochondrial import receptor subunit or translocase MFS_1 PF07690.16 KZN85558.1 - 1.7e-30 106.2 52.9 1.7e-30 106.1 49.4 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.25 KZN85559.1 - 9.5e-29 100.3 0.0 1.4e-23 83.4 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KZN85559.1 - 5.3e-22 78.5 0.0 2.4e-15 56.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KZN85559.1 - 4.2e-05 23.1 0.0 6.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KZN85559.1 - 0.0017 18.3 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 KR domain CD20 PF04103.15 KZN85560.1 - 0.00018 21.6 0.6 0.00026 21.1 0.6 1.2 1 0 0 1 1 1 1 CD20-like family DZR PF12773.7 KZN85560.1 - 0.00081 19.4 2.4 0.0018 18.3 2.4 1.6 1 0 0 1 1 1 1 Double zinc ribbon Nudix_N_2 PF14803.6 KZN85560.1 - 0.0087 16.0 6.8 0.25 11.3 0.5 2.5 2 0 0 2 2 2 2 Nudix N-terminal EphA2_TM PF14575.6 KZN85560.1 - 0.043 14.7 0.1 0.29 12.0 0.1 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain zinc_ribbon_2 PF13240.6 KZN85560.1 - 0.058 13.1 5.7 2.5 7.9 0.6 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Syndecan PF01034.20 KZN85560.1 - 1.2 9.1 7.3 0.087 12.8 1.4 2.1 2 0 0 2 2 2 0 Syndecan domain DUF1459 PF07312.11 KZN85560.1 - 1.6 9.0 12.5 5.1 7.4 3.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1459) zf-RRN7 PF11781.8 KZN85560.1 - 2 8.2 7.5 11 5.8 0.7 2.4 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-NADH-PPase PF09297.11 KZN85560.1 - 3.3 7.5 9.1 2 8.1 2.2 2.4 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DUF1772 PF08592.11 KZN85561.1 - 1.5e-07 31.8 1.7 1.5e-07 31.8 1.7 1.4 1 1 1 2 2 2 1 Domain of unknown function (DUF1772) Retrotran_gag_2 PF14223.6 KZN85563.1 - 4.2e-05 23.2 0.0 0.00011 21.9 0.0 1.7 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type eIF3g PF12353.8 KZN85563.1 - 0.025 15.0 1.8 0.055 13.9 1.8 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G DUF3627 PF12299.8 KZN85563.1 - 0.082 13.0 0.0 0.082 13.0 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3627) Fmp27_SW PF10305.9 KZN85563.1 - 0.18 12.5 1.4 1.3 9.8 0.0 2.8 3 0 0 3 3 3 0 RNA pol II promoter Fmp27 protein domain ketoacyl-synt PF00109.26 KZN85564.1 - 2e-86 289.7 0.4 5.4e-86 288.3 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KZN85564.1 - 1.1e-61 207.9 0.0 2.5e-61 206.7 0.0 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KZN85564.1 - 2.6e-61 207.9 0.0 4.6e-61 207.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KZN85564.1 - 6.2e-43 145.6 1.9 7.4e-43 145.3 0.5 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KZN85564.1 - 2.3e-13 50.1 0.1 4.7e-13 49.0 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 KZN85564.1 - 2.6e-13 50.1 0.0 8.6e-13 48.4 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KZN85564.1 - 4.9e-13 49.5 0.0 1.1e-12 48.4 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KZN85564.1 - 2.1e-06 27.3 1.1 1.3e-05 24.8 0.3 2.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain adh_short PF00106.25 KZN85564.1 - 1.2e-05 24.8 0.0 6.5e-05 22.5 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase Cupin_2 PF07883.11 KZN85565.1 - 0.00066 19.3 0.1 0.0015 18.2 0.1 1.5 1 0 0 1 1 1 1 Cupin domain p450 PF00067.22 KZN85566.1 - 3.3e-79 266.8 0.0 4.2e-79 266.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DDR PF08841.10 KZN85566.1 - 0.26 10.2 0.0 0.39 9.6 0.0 1.1 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Fungal_trans PF04082.18 KZN85567.1 - 4e-20 72.0 1.7 6.7e-20 71.2 1.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN85567.1 - 2.7e-07 30.6 10.6 7.2e-07 29.2 10.6 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.12 KZN85567.1 - 0.049 13.5 0.6 0.049 13.5 0.6 2.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Gon7 PF08738.10 KZN85567.1 - 0.086 12.9 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Gon7 family Tup_N PF08581.10 KZN85567.1 - 0.14 12.5 0.0 0.46 10.8 0.0 1.8 1 0 0 1 1 1 0 Tup N-terminal Amidohydro_2 PF04909.14 KZN85568.1 - 4.9e-30 105.3 0.6 5.8e-30 105.1 0.6 1.0 1 0 0 1 1 1 1 Amidohydrolase p450 PF00067.22 KZN85569.1 - 2.4e-76 257.3 0.0 3e-76 257.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PPR_2 PF13041.6 KZN85570.1 - 3.8e-08 33.4 0.1 5.7 7.2 0.0 7.2 8 0 0 8 8 8 3 PPR repeat family PPR PF01535.20 KZN85570.1 - 5.5e-05 23.1 3.7 0.39 11.1 0.2 6.5 7 0 0 7 7 7 1 PPR repeat PPR_long PF17177.4 KZN85570.1 - 0.00024 20.6 1.4 0.087 12.2 0.3 3.6 3 1 1 4 4 4 1 Pentacotripeptide-repeat region of PRORP Death_2 PF14786.6 KZN85570.1 - 0.067 13.1 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 Tube Death domain Mycoplasma_p37 PF06646.11 KZN85570.1 - 0.14 11.3 0.1 0.26 10.5 0.1 1.4 1 0 0 1 1 1 0 High affinity transport system protein p37 Ribosomal_S18 PF01084.20 KZN85571.1 - 1.5e-14 53.9 0.0 3.6e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 WD40 PF00400.32 KZN85572.1 - 2.4e-12 47.1 13.5 0.0011 19.7 1.5 5.9 5 1 1 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN85572.1 - 4.6e-07 30.1 2.5 0.0001 22.5 0.0 3.7 2 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 KZN85572.1 - 0.072 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FUSC_2 PF13515.6 KZN85573.1 - 6.7e-30 103.8 10.0 6.7e-30 103.8 10.0 3.0 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 KZN85573.1 - 6.9e-06 26.1 0.5 1.4e-05 25.0 0.5 1.5 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ALMT PF11744.8 KZN85573.1 - 0.0018 17.2 20.4 0.044 12.6 0.0 4.0 4 1 0 4 4 4 2 Aluminium activated malate transporter Phage_holin_3_1 PF05106.12 KZN85573.1 - 0.039 14.4 0.7 0.17 12.4 0.7 2.1 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) SLATT_fungal PF18142.1 KZN85573.1 - 0.35 10.9 2.6 0.65 10.0 0.4 2.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain Phage_holin_Dp1 PF16938.5 KZN85573.1 - 1.2 9.4 7.6 3.8 7.8 0.1 3.8 3 0 0 3 3 3 0 Putative phage holin Dp-1 VIT1 PF01988.19 KZN85573.1 - 2.3 8.0 8.1 3.5 7.4 4.9 2.7 2 0 0 2 2 2 0 VIT family SAGA-Tad1 PF12767.7 KZN85574.1 - 4.8e-54 183.6 0.0 6.3e-54 183.2 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit PRP1_N PF06424.12 KZN85575.1 - 1.9e-52 177.6 7.9 4.8e-52 176.3 7.9 1.8 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_19 PF14559.6 KZN85575.1 - 3.6e-31 107.5 12.9 1.1e-07 32.2 0.3 9.7 6 3 2 9 9 9 7 Tetratricopeptide repeat TPR_14 PF13428.6 KZN85575.1 - 8.5e-29 97.8 37.9 1.6e-05 25.3 0.2 14.1 5 4 10 15 15 13 10 Tetratricopeptide repeat TPR_16 PF13432.6 KZN85575.1 - 5.9e-15 55.6 23.7 0.00085 19.9 0.0 8.1 6 2 1 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 KZN85575.1 - 5.8e-13 47.9 12.3 0.45 10.7 0.0 9.1 10 0 0 10 10 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 KZN85575.1 - 3.9e-12 45.6 1.6 0.45 10.2 0.0 7.6 7 1 1 8 8 8 3 TPR repeat TPR_8 PF13181.6 KZN85575.1 - 2.2e-08 33.7 0.3 1.1 9.6 0.0 7.2 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 KZN85575.1 - 3.9e-08 33.1 5.3 4.8 7.8 0.0 9.2 11 1 1 12 12 9 1 Tetratricopeptide repeat TPR_1 PF00515.28 KZN85575.1 - 1.3e-07 31.2 0.6 0.67 9.9 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_21 PF09976.9 KZN85575.1 - 6.8e-05 22.7 17.6 0.023 14.4 2.9 4.7 4 1 0 4 4 4 2 Tetratricopeptide repeat-like domain TPR_15 PF13429.6 KZN85575.1 - 0.00026 20.3 28.7 0.00079 18.7 7.3 5.4 3 2 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KZN85575.1 - 0.00039 20.6 0.5 0.41 10.9 0.1 4.2 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KZN85575.1 - 0.003 17.8 6.4 9.6 6.6 0.0 7.1 7 1 1 8 8 7 0 Tetratricopeptide repeat TPR_4 PF07721.14 KZN85575.1 - 0.0071 16.9 12.0 6.9 7.6 0.1 6.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 KZN85575.1 - 0.013 15.7 11.8 1 9.5 0.1 6.0 5 1 0 5 5 5 0 Tetratricopeptide repeat Suf PF05843.14 KZN85575.1 - 0.013 15.5 4.3 4.5 7.2 0.0 3.8 4 0 0 4 4 4 0 Suppressor of forked protein (Suf) TPR_6 PF13174.6 KZN85575.1 - 0.017 15.7 13.6 74 4.3 0.0 8.8 10 0 0 10 10 8 0 Tetratricopeptide repeat PTPRCAP PF15713.5 KZN85575.1 - 0.063 13.6 7.9 0.21 11.9 7.9 1.9 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated ZNRF_3_ecto PF18212.1 KZN85575.1 - 0.079 13.0 0.2 30 4.7 0.0 3.8 4 0 0 4 4 4 0 ZNRF-3 Ectodomain TPR_7 PF13176.6 KZN85575.1 - 0.1 12.7 1.8 36 4.7 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat AdenylateSensor PF16579.5 KZN85575.1 - 0.18 12.3 0.9 30 5.1 0.0 3.7 3 1 1 4 4 3 0 Adenylate sensor of SNF1-like protein kinase RrnaAD PF00398.20 KZN85576.1 - 1.4e-64 217.8 0.0 4.4e-64 216.1 0.0 1.7 1 1 1 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KZN85576.1 - 6.4e-08 33.2 0.0 1.5e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN85576.1 - 2.3e-05 25.0 0.0 5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KZN85576.1 - 2.4e-05 24.2 0.0 4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KZN85576.1 - 0.00029 20.7 0.0 0.00052 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN85576.1 - 0.00035 20.4 0.0 0.00059 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN85576.1 - 0.00053 20.7 0.0 0.0012 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KZN85576.1 - 0.0016 17.8 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KZN85576.1 - 0.0053 16.3 0.0 0.0099 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KZN85576.1 - 0.0061 15.9 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_28 PF02636.17 KZN85576.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.17 KZN85576.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_18 PF12847.7 KZN85576.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RRM_1 PF00076.22 KZN85578.1 - 1.9e-33 114.1 0.1 2e-15 56.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KZN85578.1 - 2.3e-11 43.6 0.1 5.3e-05 23.2 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KZN85578.1 - 0.0019 18.1 0.0 0.76 9.8 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KZN85578.1 - 0.05 13.7 4.7 1.1 9.3 0.0 2.9 3 0 0 3 3 3 0 RNA binding motif TRP PF06011.12 KZN85579.1 - 7e-138 459.9 11.2 9.9e-138 459.4 11.2 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KZN85579.1 - 5.1e-40 137.1 0.2 8.5e-40 136.3 0.2 1.4 1 0 0 1 1 1 1 ML-like domain TMEM154 PF15102.6 KZN85579.1 - 0.00011 22.1 0.9 1.9 8.4 0.1 3.5 3 0 0 3 3 3 2 TMEM154 protein family Shisa PF13908.6 KZN85579.1 - 0.00021 21.6 0.4 0.49 10.6 0.3 2.7 2 0 0 2 2 2 2 Wnt and FGF inhibitory regulator DUF3169 PF11368.8 KZN85579.1 - 0.0025 17.4 5.7 0.016 14.7 2.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3169) DUF2663 PF10864.8 KZN85579.1 - 0.025 15.0 1.7 0.025 15.0 1.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2663) Collectrin PF16959.5 KZN85579.1 - 0.054 13.3 0.1 0.23 11.2 0.1 2.2 1 0 0 1 1 1 0 Renal amino acid transporter ETRAMP PF09716.10 KZN85579.1 - 0.063 13.4 0.0 0.063 13.4 0.0 3.2 4 0 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) Pox_A28 PF04584.14 KZN85579.1 - 0.11 12.7 0.8 0.52 10.5 0.8 2.2 1 0 0 1 1 1 0 Poxvirus A28 family HTH_32 PF13565.6 KZN85580.1 - 1.9e-07 31.6 2.8 0.0024 18.5 0.0 2.4 1 1 1 2 2 2 2 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KZN85580.1 - 0.0086 16.3 0.0 0.021 15.0 0.0 1.6 1 0 0 1 1 1 1 Transposase DLEU7 PF15760.5 KZN85580.1 - 0.14 11.7 0.5 0.41 10.1 0.1 1.8 2 0 0 2 2 2 0 Leukemia-associated protein 7 WD40 PF00400.32 KZN85581.1 - 4e-49 163.5 17.9 2.3e-11 44.0 0.4 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN85581.1 - 3.9e-18 65.5 0.1 1.2e-05 25.5 0.0 5.8 3 1 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KZN85581.1 - 1.6e-07 31.4 0.0 0.0012 18.7 0.0 3.2 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KZN85581.1 - 1e-06 27.7 1.0 0.92 8.1 0.0 4.6 2 2 3 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KZN85581.1 - 2.4e-05 23.5 0.1 3.4 6.6 0.0 4.6 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KZN85581.1 - 0.0048 16.3 0.0 0.31 10.3 0.0 2.7 2 1 1 3 3 3 1 WD40-like domain IKI3 PF04762.12 KZN85581.1 - 0.0055 14.8 0.0 0.0074 14.4 0.0 1.1 1 0 0 1 1 1 1 IKI3 family Nbas_N PF15492.6 KZN85581.1 - 0.058 12.7 0.3 12 5.1 0.1 3.1 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PALB2_WD40 PF16756.5 KZN85581.1 - 0.13 11.1 0.3 0.71 8.7 0.0 2.4 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain CAP_N PF01213.19 KZN85581.1 - 0.32 10.4 2.2 0.6 9.5 2.2 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 KZN85581.1 - 0.43 10.6 3.6 0.96 9.5 3.6 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Exo_endo_phos PF03372.23 KZN85582.1 - 6.7e-15 55.2 0.0 1.5e-14 54.1 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Luciferase_cat PF10285.9 KZN85582.1 - 0.084 12.2 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Luciferase catalytic domain Thi4 PF01946.17 KZN85583.1 - 3.7e-110 366.7 0.0 4.6e-110 366.4 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KZN85583.1 - 6.1e-08 32.6 0.4 1.9e-07 31.0 0.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KZN85583.1 - 2.1e-05 24.6 0.7 6.2e-05 23.2 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KZN85583.1 - 4.7e-05 22.6 0.2 8e-05 21.9 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KZN85583.1 - 0.0005 20.1 0.2 0.002 18.1 0.1 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KZN85583.1 - 0.00072 18.9 0.0 0.00099 18.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KZN85583.1 - 0.001 18.2 1.8 0.0085 15.2 0.9 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 KZN85583.1 - 0.0061 15.9 0.1 0.01 15.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KZN85583.1 - 0.03 13.7 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KZN85583.1 - 0.052 12.8 0.0 0.083 12.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KZN85583.1 - 0.11 11.1 0.1 0.39 9.4 0.5 1.6 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.14 KZN85583.1 - 0.15 10.9 0.2 0.21 10.4 0.2 1.1 1 0 0 1 1 1 0 Tryptophan halogenase MFS_1 PF07690.16 KZN85584.1 - 5.2e-31 107.9 28.6 5.2e-31 107.9 28.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KZN85584.1 - 0.0071 15.2 0.9 0.0071 15.2 0.9 2.3 3 1 0 3 3 3 1 MFS_1 like family SWI-SNF_Ssr4 PF08549.10 KZN85585.1 - 2.5e-229 763.6 24.1 3.6e-214 713.5 5.5 2.9 1 1 2 3 3 3 3 Fungal domain of unknown function (DUF1750) Pil1 PF13805.6 KZN85586.1 - 1.3e-98 329.7 6.1 1.6e-98 329.4 6.1 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 BAR_3 PF16746.5 KZN85586.1 - 0.063 13.0 2.5 0.1 12.3 0.9 2.1 2 1 0 2 2 2 0 BAR domain of APPL family Spectrin PF00435.21 KZN85586.1 - 0.11 13.0 2.5 0.62 10.6 1.0 2.5 2 1 0 2 2 2 0 Spectrin repeat KIP1 PF07765.12 KZN85586.1 - 0.41 10.8 1.8 1.7 8.8 0.1 2.7 2 1 1 3 3 3 0 KIP1-like protein CCDC-167 PF15188.6 KZN85586.1 - 0.89 9.9 4.7 1.4 9.4 0.6 2.9 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 APG6_N PF17675.1 KZN85586.1 - 2.3 8.8 7.2 24 5.4 4.6 2.5 2 1 0 2 2 2 0 Apg6 coiled-coil region DivIC PF04977.15 KZN85586.1 - 2.6 7.9 8.0 0.65 9.8 0.2 2.8 2 1 0 2 2 2 0 Septum formation initiator Proteasome PF00227.26 KZN85587.1 - 3.7e-42 144.0 0.6 3e-40 137.8 0.6 2.1 1 1 0 1 1 1 1 Proteasome subunit Zn_clus PF00172.18 KZN85588.1 - 4.3e-07 30.0 9.3 7.2e-07 29.2 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN85588.1 - 1.3e-05 24.4 2.5 3.4e-05 23.0 0.4 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Alpha-amylase PF00128.24 KZN85589.1 - 6.2e-118 394.2 3.3 2.4e-115 385.7 0.5 2.0 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KZN85589.1 - 2.3e-07 30.8 0.0 6.8e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain MAM33 PF02330.16 KZN85589.1 - 0.0021 18.0 1.4 0.0039 17.1 1.1 1.5 2 0 0 2 2 2 1 Mitochondrial glycoprotein Cyc-maltodext_C PF10438.9 KZN85589.1 - 0.024 14.7 0.2 0.058 13.5 0.2 1.6 1 0 0 1 1 1 0 Cyclo-malto-dextrinase C-terminal domain Staygreen PF12638.7 KZN85589.1 - 0.091 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Staygreen protein Sugar_tr PF00083.24 KZN85590.1 - 8.6e-90 301.8 25.9 1e-89 301.5 25.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN85590.1 - 5.2e-22 78.3 23.5 5.2e-22 78.3 23.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KZN85590.1 - 0.089 11.6 11.7 0.0058 15.5 4.1 2.1 2 0 0 2 2 2 0 MFS_1 like family RNA_pol_Rpb2_6 PF00562.28 KZN85591.1 - 1.4e-115 386.5 0.4 1.9e-115 386.0 0.4 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KZN85591.1 - 3.9e-36 124.5 0.0 6.1e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 KZN85591.1 - 3.3e-27 94.5 0.0 7.8e-27 93.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 KZN85591.1 - 3.4e-26 91.0 0.1 7.8e-26 89.9 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 KZN85591.1 - 1.5e-24 86.7 0.0 2.9e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KZN85591.1 - 4.2e-15 55.9 0.0 3e-14 53.2 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 Arf PF00025.21 KZN85592.1 - 1.7e-43 148.1 0.0 2e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KZN85592.1 - 5.4e-19 68.4 0.0 6.2e-19 68.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KZN85592.1 - 3.3e-15 56.4 0.0 4.7e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KZN85592.1 - 3e-08 33.7 0.0 4.7e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KZN85592.1 - 5.2e-07 29.3 0.0 6.3e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KZN85592.1 - 1.7e-05 24.4 0.0 1.8e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KZN85592.1 - 0.00017 20.9 0.1 0.00096 18.4 0.0 2.3 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1_Xtn PF16897.5 KZN85592.1 - 0.0035 17.3 0.0 0.0056 16.7 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 KZN85592.1 - 0.0084 16.2 0.1 0.056 13.5 0.1 2.0 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.18 KZN85592.1 - 0.023 14.2 0.2 0.091 12.3 0.0 1.9 2 1 0 2 2 2 0 Ferrous iron transport protein B DUF1979 PF09322.10 KZN85592.1 - 0.061 13.2 0.5 3.2 7.7 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1979) RsgA_GTPase PF03193.16 KZN85592.1 - 0.093 12.6 0.1 11 5.9 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Actin PF00022.19 KZN85593.1 - 1.1e-147 491.9 0.0 1.3e-147 491.7 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KZN85593.1 - 0.036 12.9 0.0 1.4 7.7 0.0 2.7 3 0 0 3 3 3 0 MreB/Mbl protein Hep_59 PF07052.11 KZN85594.1 - 1.1e-18 67.9 4.3 1.5e-18 67.5 0.0 2.8 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Sugar_tr PF00083.24 KZN85595.1 - 4.1e-98 329.2 22.2 4.8e-98 329.0 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN85595.1 - 1.1e-29 103.5 41.4 3.5e-25 88.7 21.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily SfLAP PF11139.8 KZN85595.1 - 0.038 13.4 4.6 2.7 7.4 0.2 3.1 2 2 0 2 2 2 0 Sap, sulfolipid-1-addressing protein TRI12 PF06609.13 KZN85595.1 - 0.062 11.7 8.4 0.016 13.7 1.8 2.3 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Herpes_LMP1 PF05297.11 KZN85596.1 - 7.3 5.7 7.4 11 5.1 7.4 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) GMC_oxred_N PF00732.19 KZN85597.1 - 2.5e-30 105.9 0.0 9.5e-19 67.9 0.0 3.2 2 1 1 3 3 3 3 GMC oxidoreductase GMC_oxred_C PF05199.13 KZN85597.1 - 6.9e-29 101.2 0.0 1.2e-28 100.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KZN85597.1 - 0.00032 20.9 0.0 0.00083 19.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KZN85597.1 - 0.00044 19.6 0.0 0.0013 18.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KZN85597.1 - 0.0024 17.0 0.9 0.011 14.9 1.4 1.7 2 0 0 2 2 2 1 FAD binding domain HHH PF00633.23 KZN85597.1 - 0.013 15.4 0.2 5.1 7.2 0.0 3.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif Pyr_redox_3 PF13738.6 KZN85597.1 - 0.03 13.6 0.0 4.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KZN85597.1 - 0.12 11.9 1.8 1.2 8.6 2.1 2.2 2 1 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KZN85597.1 - 0.14 11.2 0.4 0.22 10.5 0.4 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein CFEM PF05730.11 KZN85598.1 - 6e-14 51.9 12.9 1e-13 51.1 12.9 1.4 1 0 0 1 1 1 1 CFEM domain Abhydrolase_9_N PF15420.6 KZN85598.1 - 1.7 8.6 8.5 1.2 9.1 1.3 2.4 2 1 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Peroxidase_2 PF01328.17 KZN85599.1 - 7.3e-49 166.8 0.0 9.8e-49 166.4 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Beta-lactamase PF00144.24 KZN85600.1 - 3.2e-30 105.5 0.0 5.4e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase Acyl-CoA_dh_M PF02770.19 KZN85602.1 - 0.001 19.2 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DIOX_N PF14226.6 KZN85603.1 - 3.8e-18 66.4 0.0 9.3e-18 65.1 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KZN85603.1 - 2.6e-13 50.3 0.0 4.5e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_7 PF13176.6 KZN85604.1 - 4.4e-07 29.5 5.6 0.02 14.9 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KZN85604.1 - 1.2e-06 28.7 7.7 0.12 12.6 1.2 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KZN85604.1 - 2.2e-06 27.2 0.3 2.2e-06 27.2 0.3 5.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 KZN85604.1 - 1e-05 25.1 9.7 0.004 16.8 0.2 4.6 6 0 0 6 6 6 2 TPR repeat TPR_2 PF07719.17 KZN85604.1 - 3.9e-05 23.4 25.5 5.1e-05 23.1 0.2 6.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 KZN85604.1 - 8.1e-05 22.5 5.0 0.29 11.5 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KZN85604.1 - 0.0012 19.5 8.8 4.3 8.4 0.0 6.1 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KZN85604.1 - 0.024 15.1 12.2 0.058 13.9 0.3 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KZN85604.1 - 0.065 12.6 1.1 0.54 9.6 0.4 2.3 2 0 0 2 2 2 0 MalT-like TPR region TPR_16 PF13432.6 KZN85604.1 - 0.35 11.6 12.5 12 6.6 0.0 5.6 7 1 0 7 7 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 KZN85604.1 - 1.1 9.2 9.4 12 5.9 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KZN85604.1 - 1.6 9.0 13.0 10 6.4 2.3 4.5 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Rhodanese PF00581.20 KZN85606.1 - 2.6e-30 105.1 0.0 4.3e-07 30.4 0.0 4.4 4 0 0 4 4 4 4 Rhodanese-like domain DUF2263 PF10021.9 KZN85607.1 - 7.2e-22 78.3 0.0 1.8e-21 77.1 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) SKG6 PF08693.10 KZN85608.1 - 0.00042 19.7 0.0 0.00079 18.8 0.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.12 KZN85608.1 - 0.0054 16.6 0.0 0.0083 16.0 0.0 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Glyco_hydro_15 PF00723.21 KZN85609.1 - 2.6e-18 66.0 0.0 3.2e-18 65.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 His_Phos_2 PF00328.22 KZN85610.1 - 1.2e-39 136.8 0.0 1.4e-39 136.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) adh_short PF00106.25 KZN85611.1 - 9.8e-09 34.9 0.0 1.5e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN85611.1 - 0.002 18.0 0.0 0.0031 17.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KZN85611.1 - 0.041 13.4 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase OrsD PF12013.8 KZN85612.1 - 6.3e-22 78.2 0.8 1.1e-21 77.4 0.8 1.4 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D Fungal_trans_2 PF11951.8 KZN85612.1 - 4.4e-12 45.5 0.0 1.1e-11 44.1 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain FAD_binding_4 PF01565.23 KZN85613.1 - 2.4e-23 82.4 0.7 4.1e-23 81.7 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KZN85613.1 - 2.5e-05 24.3 0.0 7.4e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_5 PF00941.21 KZN85613.1 - 0.19 11.4 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase MFS_1 PF07690.16 KZN85615.1 - 1.1e-28 100.2 23.2 1.1e-28 100.2 23.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KZN85615.1 - 0.0024 16.4 0.7 0.0048 15.4 0.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Polyketide_cyc2 PF10604.9 KZN85616.1 - 6.8e-10 39.4 0.0 9e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Zn_clus PF00172.18 KZN85617.1 - 2.2e-07 30.9 10.4 3.4e-07 30.3 10.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KZN85618.1 - 4.3e-49 167.5 0.0 5.9e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PIG-X PF08320.12 KZN85618.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 PIG-X / PBN1 Response_reg PF00072.24 KZN85619.1 - 7.1e-23 80.9 0.3 1.5e-22 79.8 0.3 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KZN85619.1 - 5.7e-22 78.3 0.1 1.1e-21 77.4 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KZN85619.1 - 7.1e-10 38.8 0.0 2e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 KZN85619.1 - 6.7e-05 23.1 0.1 0.00022 21.4 0.0 2.0 1 1 1 2 2 2 1 PAS fold PAS_3 PF08447.12 KZN85619.1 - 0.0016 18.7 0.0 0.0034 17.6 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_7 PF12860.7 KZN85619.1 - 0.0031 17.7 0.1 1.2 9.3 0.0 3.2 2 1 1 3 3 3 1 PAS fold HATPase_c_5 PF14501.6 KZN85619.1 - 0.44 10.5 2.7 2.5 8.1 0.1 3.0 2 1 0 2 2 2 0 GHKL domain MFS_1 PF07690.16 KZN85620.1 - 3.6e-46 157.7 53.5 8.1e-46 156.6 51.0 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily FAD_binding_3 PF01494.19 KZN85621.1 - 1.2e-21 77.3 1.9 1.4e-19 70.5 1.9 2.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KZN85621.1 - 4.7e-06 26.0 0.0 0.0025 17.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KZN85621.1 - 1.6e-05 24.3 0.1 3.8e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KZN85621.1 - 2.3e-05 23.7 0.0 4.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KZN85621.1 - 6.7e-05 23.0 0.0 0.00023 21.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KZN85621.1 - 0.00058 19.0 0.0 0.0018 17.4 0.0 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 KZN85621.1 - 0.0016 17.2 0.1 0.0056 15.4 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KZN85621.1 - 0.0025 17.5 0.3 0.0043 16.7 0.3 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KZN85621.1 - 0.021 15.4 0.0 2.6 8.6 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KZN85621.1 - 0.027 13.7 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 KZN85621.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain IlvN PF07991.12 KZN85621.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain PALP PF00291.25 KZN85621.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Glyco_transf_25 PF01755.17 KZN85622.1 - 0.00043 20.2 0.0 0.17 11.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Sugar_tr PF00083.24 KZN85623.1 - 2.9e-87 293.4 22.6 3.6e-87 293.1 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN85623.1 - 8e-23 80.9 33.2 8e-23 80.9 33.2 2.3 1 1 2 3 3 3 1 Major Facilitator Superfamily TRI12 PF06609.13 KZN85623.1 - 1.6e-05 23.6 1.6 1.6e-05 23.6 1.6 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) SCP2_2 PF13530.6 KZN85623.1 - 0.18 12.2 0.0 0.49 10.8 0.0 1.7 1 0 0 1 1 1 0 Sterol carrier protein domain DUF2530 PF10745.9 KZN85623.1 - 2.7 8.3 12.1 0.05 13.9 3.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) OATP PF03137.20 KZN85623.1 - 5.4 5.2 11.8 3.3 5.9 1.3 3.0 2 1 2 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.22 KZN85625.1 - 2.9e-72 243.9 0.0 3.5e-72 243.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyoxalase PF00903.25 KZN85627.1 - 1.1e-05 25.6 3.9 2.2e-05 24.6 1.9 2.3 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAA_hydrolase PF01557.18 KZN85628.1 - 4.1e-61 206.4 0.0 6.3e-61 205.8 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family p450 PF00067.22 KZN85629.1 - 1.8e-53 181.9 0.0 2.2e-53 181.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 KZN85630.1 - 7.7e-95 318.1 0.0 9.4e-95 317.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KZN85630.1 - 1.1e-05 24.9 0.0 2.6e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KZN85630.1 - 0.00012 21.8 1.6 0.21 11.2 1.1 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KZN85630.1 - 0.0091 16.2 0.1 0.022 15.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KZN85630.1 - 0.013 14.8 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 KZN85630.1 - 0.034 13.5 0.2 0.057 12.8 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KZN85630.1 - 0.036 13.1 0.1 0.25 10.4 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 KZN85630.1 - 0.042 12.9 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KZN85630.1 - 0.053 12.8 0.0 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KZN85630.1 - 0.19 12.3 0.0 5 7.8 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KZN85630.1 - 0.19 10.4 0.1 0.35 9.5 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Epimerase PF01370.21 KZN85631.1 - 0.00035 20.1 0.0 0.0017 17.8 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KZN85631.1 - 0.00085 19.6 0.0 0.0015 18.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 KZN85631.1 - 0.0095 15.1 0.0 0.31 10.2 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 KZN85631.1 - 0.02 14.8 0.0 0.035 14.0 0.0 1.5 1 1 0 1 1 1 0 NAD(P)H-binding DUF1456 PF07308.13 KZN85631.1 - 0.048 14.0 0.0 0.088 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) KR PF08659.10 KZN85631.1 - 0.065 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 KR domain Fungal_trans PF04082.18 KZN85632.1 - 1.1e-15 57.4 0.0 2.3e-15 56.4 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KZN85632.1 - 1.9e-07 31.2 12.5 0.00022 21.5 0.5 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type Zn_clus PF00172.18 KZN85632.1 - 2.2e-07 30.9 7.4 5.1e-07 29.7 7.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 KZN85632.1 - 2.1e-05 25.0 13.3 0.0031 18.2 0.9 3.5 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KZN85632.1 - 2.9e-05 23.7 6.2 0.038 13.7 0.8 2.8 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 KZN85632.1 - 9.4e-05 22.7 8.4 0.00097 19.5 0.1 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-Di19 PF05605.12 KZN85632.1 - 0.00011 22.4 1.5 0.00027 21.1 1.5 1.7 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KZN85632.1 - 0.00041 20.6 0.7 0.14 12.5 0.2 2.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KZN85632.1 - 0.0081 16.4 0.3 0.58 10.5 0.2 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KZN85632.1 - 0.024 14.6 2.9 4.9 7.3 0.7 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Zn-C2H2_12 PF18112.1 KZN85632.1 - 0.094 13.2 0.3 0.55 10.8 0.1 2.3 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-BED PF02892.15 KZN85632.1 - 0.74 9.9 4.0 8.6 6.5 4.0 2.5 1 1 0 1 1 1 0 BED zinc finger ADH_zinc_N PF00107.26 KZN85633.1 - 3.1e-23 82.2 0.1 5.5e-23 81.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KZN85633.1 - 6.2e-19 69.4 0.0 1.2e-18 68.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KZN85633.1 - 0.00017 21.4 0.3 0.028 14.3 0.0 2.9 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain DapB_N PF01113.20 KZN85633.1 - 0.13 12.4 0.1 1.4 9.0 0.1 2.1 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus PE_PPE_C PF12484.8 KZN85633.1 - 0.13 13.2 2.8 0.33 11.9 2.8 1.7 1 0 0 1 1 1 0 Polymorphic PE/PPE proteins C terminal Cupin_2 PF07883.11 KZN85634.1 - 0.00024 20.7 0.0 0.0004 20.0 0.0 1.4 1 0 0 1 1 1 1 Cupin domain 4HBT_3 PF13622.6 KZN85635.1 - 2.9e-59 201.3 0.7 3.6e-59 201.0 0.7 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KZN85635.1 - 7.5e-21 74.3 0.0 1.3e-15 57.4 0.0 3.1 2 1 0 2 2 2 2 Acyl-CoA thioesterase Aa_trans PF01490.18 KZN85636.1 - 3.7e-47 160.9 33.3 4.2e-47 160.8 33.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Vma12 PF11712.8 KZN85636.1 - 9.3 6.3 7.2 0.59 10.2 0.9 2.2 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase SH3_6 PF12913.7 KZN85637.1 - 0.13 11.8 0.0 3.3 7.3 0.0 2.4 2 0 0 2 2 2 0 SH3 domain (SH3b1 type) Glyco_hydro_cc PF11790.8 KZN85638.1 - 2.1e-68 230.5 1.0 2.4e-68 230.3 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Frataxin_Cyay PF01491.16 KZN85639.1 - 6.7e-35 119.4 0.0 9.9e-35 118.9 0.0 1.3 1 0 0 1 1 1 1 Frataxin-like domain zf-CSL PF05207.13 KZN85640.1 - 7e-23 80.1 0.3 9.2e-23 79.7 0.3 1.2 1 0 0 1 1 1 1 CSL zinc finger HAUS4 PF14735.6 KZN85641.1 - 3.9e-05 23.5 3.0 3.9e-05 23.5 3.0 1.9 2 1 0 2 2 2 1 HAUS augmin-like complex subunit 4 DUF1843 PF08898.10 KZN85641.1 - 0.045 14.2 3.2 0.15 12.6 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Ku_C PF03730.14 KZN85641.1 - 2.2 9.0 5.5 1.1 10.0 1.2 2.8 3 1 0 3 3 3 0 Ku70/Ku80 C-terminal arm FXR_C1 PF16096.5 KZN85641.1 - 3.6 7.8 6.8 8 6.7 4.5 2.3 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 Bromodomain PF00439.25 KZN85642.1 - 2.6e-38 130.0 0.7 6.6e-20 71.0 0.1 2.6 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KZN85642.1 - 7e-21 74.2 1.3 1.5e-20 73.1 1.3 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF3573 PF12097.8 KZN85642.1 - 2.5 6.8 4.9 4.1 6.1 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Utp12 PF04003.12 KZN85643.1 - 2.6e-24 85.6 0.0 4.2e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KZN85643.1 - 0.059 13.7 0.0 37 4.7 0.0 3.9 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain ANAPC4_WD40 PF12894.7 KZN85645.1 - 9.1e-07 29.1 0.0 0.082 13.2 0.0 4.0 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KZN85645.1 - 9.8e-07 29.4 0.3 0.0066 17.3 0.0 5.5 5 0 0 5 5 5 1 WD domain, G-beta repeat PPTA PF01239.22 KZN85646.1 - 2e-30 103.6 7.5 6.5e-08 32.0 0.0 4.5 4 0 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat RabGAP-TBC PF00566.18 KZN85647.1 - 4e-51 173.7 0.0 4e-51 173.7 0.0 2.6 3 1 0 3 3 3 1 Rab-GTPase-TBC domain Z1 PF10593.9 KZN85647.1 - 1.5 8.3 6.5 3.1 7.2 6.5 1.5 1 0 0 1 1 1 0 Z1 domain YabA PF06156.13 KZN85647.1 - 5.9 7.6 17.6 2.2 9.0 3.4 3.7 1 1 2 3 3 3 0 Initiation control protein YabA Dabb PF07876.12 KZN85648.1 - 2.9e-13 50.3 0.0 3.1e-13 50.1 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Nepo_coat_N PF03689.15 KZN85648.1 - 0.033 14.1 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Nepovirus coat protein, N-terminal domain Glyoxalase PF00903.25 KZN85649.1 - 1.7e-16 60.6 0.1 2.3e-13 50.4 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KZN85649.1 - 1.3e-11 44.8 0.0 4.3e-05 23.8 0.0 2.8 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KZN85649.1 - 2.6e-06 27.7 0.0 0.12 12.5 0.0 3.2 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 KZN85649.1 - 1.5e-05 25.2 0.0 0.016 15.4 0.0 3.0 3 0 0 3 3 3 2 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal DUF1338 PF07063.13 KZN85649.1 - 0.025 13.8 0.1 0.26 10.4 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1338) Ctf8 PF09696.10 KZN85650.1 - 2.6e-44 151.0 0.1 3.5e-43 147.4 0.1 2.0 1 1 0 1 1 1 1 Ctf8 NHR2 PF08788.11 KZN85650.1 - 0.0016 18.2 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 NHR2 domain like Cnl2_NKP2 PF09447.10 KZN85651.1 - 8.5e-26 89.9 0.6 8.5e-26 89.9 0.6 1.9 2 0 0 2 2 2 1 Cnl2/NKP2 family protein DUF948 PF06103.11 KZN85651.1 - 0.017 15.4 0.4 0.042 14.1 0.1 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CdvA PF18822.1 KZN85651.1 - 0.045 13.6 3.2 0.37 10.6 1.1 2.3 2 0 0 2 2 2 0 CdvA-like coiled-coil domain DUF4407 PF14362.6 KZN85651.1 - 0.1 11.9 1.0 0.13 11.6 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ABC_tran_CTD PF16326.5 KZN85651.1 - 0.13 12.6 4.0 2.3 8.5 1.8 2.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain GlutR_dimer PF00745.20 KZN85651.1 - 0.19 12.2 4.4 0.1 13.1 1.4 2.1 2 1 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF2203 PF09969.9 KZN85651.1 - 0.19 12.5 1.3 0.98 10.1 0.3 2.1 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Phage_Mu_Gam PF07352.12 KZN85651.1 - 0.44 10.4 3.6 13 5.6 1.0 2.2 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein XhlA PF10779.9 KZN85651.1 - 5.5 7.3 6.0 2 8.7 0.2 2.4 2 1 0 2 2 2 0 Haemolysin XhlA MRG PF05712.13 KZN85652.1 - 9e-56 188.3 0.1 1.4e-55 187.7 0.1 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KZN85652.1 - 1.5e-08 34.4 2.2 3.1e-08 33.4 2.2 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 KZN85652.1 - 0.1 12.6 1.5 0.29 11.1 1.5 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF1741 PF08427.10 KZN85653.1 - 1.5e-92 309.5 0.0 2.4e-92 308.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) MBOAT_2 PF13813.6 KZN85653.1 - 0.11 12.8 0.1 0.32 11.3 0.1 1.8 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family Fe-S_biosyn PF01521.20 KZN85654.1 - 8.3e-19 67.8 0.0 1.1e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF2407_C PF13373.6 KZN85655.1 - 5.3e-43 146.6 0.3 8.1e-43 146.0 0.3 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 KZN85655.1 - 5.5e-36 123.3 0.1 1.6e-35 121.8 0.0 1.8 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KZN85655.1 - 0.0015 18.2 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 KZN85655.1 - 0.17 12.0 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like V-SNARE PF05008.15 KZN85656.1 - 4e-21 75.2 5.1 4e-21 75.2 5.1 2.4 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KZN85656.1 - 1.8e-15 57.0 4.4 1.8e-15 57.0 4.4 2.9 3 1 0 3 3 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KZN85656.1 - 0.00053 19.8 0.5 0.00053 19.8 0.5 2.5 2 1 1 3 3 3 1 Sec20 Fusion_gly PF00523.18 KZN85656.1 - 0.00094 17.5 3.4 0.0011 17.3 0.2 2.2 2 0 0 2 2 2 1 Fusion glycoprotein F0 Thump_like PF18096.1 KZN85656.1 - 0.0038 17.1 0.0 0.0071 16.3 0.0 1.4 1 0 0 1 1 1 1 THUMP domain-like LMBR1 PF04791.16 KZN85656.1 - 0.0048 15.9 2.7 0.0056 15.7 2.7 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein SNARE PF05739.19 KZN85656.1 - 0.016 15.2 0.9 0.016 15.2 0.9 2.1 2 0 0 2 2 2 0 SNARE domain BORCS8 PF10167.9 KZN85656.1 - 0.034 14.1 2.0 0.7 9.9 0.0 2.4 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 YqjK PF13997.6 KZN85656.1 - 0.11 12.7 8.7 1.1 9.6 0.0 3.3 3 0 0 3 3 3 0 YqjK-like protein CHDCT2 PF08074.11 KZN85656.1 - 0.16 12.1 3.6 0.77 9.9 0.2 2.2 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain TMP_2 PF06791.13 KZN85656.1 - 0.43 10.2 4.5 1 9.0 0.4 2.2 2 0 0 2 2 2 0 Prophage tail length tape measure protein MscS_porin PF12795.7 KZN85656.1 - 1.6 8.2 25.9 0.67 9.5 11.7 2.1 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain EMC3_TMCO1 PF01956.16 KZN85656.1 - 2.1 8.0 5.7 1.5 8.5 1.0 2.4 1 1 1 2 2 2 0 Integral membrane protein EMC3/TMCO1-like zf-C4H2 PF10146.9 KZN85656.1 - 2.7 8.3 10.7 38 4.5 10.7 2.2 1 1 0 1 1 1 0 Zinc finger-containing protein Prominin PF05478.11 KZN85656.1 - 2.9 5.7 10.4 2.2 6.1 4.4 2.0 1 1 1 2 2 2 0 Prominin Synaptobrevin PF00957.21 KZN85656.1 - 4 7.3 10.2 0.49 10.2 3.0 2.9 3 1 1 4 4 4 0 Synaptobrevin Exonuc_VII_L PF02601.15 KZN85656.1 - 4.1 6.9 16.3 35 3.8 16.3 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit End3 PF12761.7 KZN85656.1 - 5.2 7.2 14.8 0.41 10.8 8.1 2.0 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 DUF4083 PF13314.6 KZN85656.1 - 8.9 6.4 8.1 21 5.1 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) TIP49 PF06068.13 KZN85657.1 - 1.7e-167 557.0 0.0 2e-167 556.8 0.0 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KZN85657.1 - 7.9e-19 67.6 0.0 2.4e-18 66.0 0.0 1.9 2 0 0 2 2 1 1 TIP49 AAA-lid domain AAA PF00004.29 KZN85657.1 - 3.6e-11 43.6 0.1 3.8e-07 30.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KZN85657.1 - 2e-10 40.7 0.1 7.3e-07 29.1 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KZN85657.1 - 7.3e-06 26.3 0.1 0.043 14.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KZN85657.1 - 0.00012 22.5 0.1 0.0016 18.9 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KZN85657.1 - 0.00014 22.3 0.7 0.086 13.2 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KZN85657.1 - 0.00079 19.4 0.1 0.19 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KZN85657.1 - 0.00091 19.5 0.1 0.0019 18.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KZN85657.1 - 0.0014 18.4 0.1 1.4 8.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.12 KZN85657.1 - 0.0061 15.9 0.3 0.015 14.6 0.3 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.6 KZN85657.1 - 0.0075 15.9 0.1 0.016 14.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KZN85657.1 - 0.016 14.6 0.1 0.76 9.1 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DnaB_C PF03796.15 KZN85657.1 - 0.04 13.2 0.1 0.1 11.9 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_14 PF13173.6 KZN85657.1 - 0.042 13.9 0.0 0.66 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KZN85657.1 - 0.048 13.0 0.7 0.15 11.4 0.1 1.9 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.6 KZN85657.1 - 0.057 14.0 0.0 0.28 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KZN85657.1 - 0.057 13.2 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 KZN85657.1 - 0.071 12.3 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KZN85657.1 - 0.1 12.1 0.1 0.43 10.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 KZN85657.1 - 0.11 12.2 0.2 1.7 8.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain TetR_C_30 PF17939.1 KZN85657.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Ribosomal_L28 PF00830.19 KZN85658.1 - 3.9e-17 62.2 1.1 6.8e-17 61.4 1.1 1.3 1 0 0 1 1 1 1 Ribosomal L28 family UPF0147 PF03685.13 KZN85659.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) CN_hydrolase PF00795.22 KZN85660.1 - 4e-34 118.1 0.0 6.2e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Glyco_transf_34 PF05637.12 KZN85661.1 - 3.1e-59 200.6 0.0 3.9e-59 200.3 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Steroid_dh PF02544.16 KZN85662.1 - 6.7e-33 113.8 1.7 9e-33 113.4 1.7 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KZN85662.1 - 2.9e-06 27.0 1.6 4.1e-06 26.5 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KZN85662.1 - 0.001 19.4 1.2 0.0018 18.6 0.5 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase An_peroxidase PF03098.15 KZN85663.1 - 4.3e-39 134.5 0.0 2e-28 99.3 0.0 3.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KZN85663.1 - 3.9e-08 32.5 0.0 2.5e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Cytochrome P450 DUF913 PF06025.12 KZN85664.1 - 1.8e-129 431.9 0.0 1.8e-129 431.9 0.0 5.6 5 1 0 5 5 5 2 Domain of Unknown Function (DUF913) DUF908 PF06012.12 KZN85664.1 - 1.2e-113 380.2 3.7 1.2e-113 380.2 3.7 2.6 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) HECT PF00632.25 KZN85664.1 - 3.3e-95 319.1 0.0 5.5e-95 318.4 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 KZN85664.1 - 5.9e-29 98.6 22.9 2.2e-10 39.6 2.4 4.1 3 0 0 3 3 3 3 Ubiquitin binding region DUF2151 PF10221.9 KZN85664.1 - 0.66 8.5 5.3 1.4 7.5 5.3 1.4 1 0 0 1 1 1 0 Cell cycle and development regulator Pribosyltran_N PF13793.6 KZN85665.1 - 9.8e-46 154.5 0.5 1.1e-44 151.0 0.1 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KZN85665.1 - 2e-39 135.6 1.7 1.2e-32 113.5 0.6 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KZN85665.1 - 1.5e-16 60.3 1.3 2e-15 56.7 0.7 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KZN85665.1 - 0.00011 21.7 0.2 0.00021 20.8 0.2 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Chlorosome_CsmC PF11098.8 KZN85665.1 - 0.12 12.3 1.5 0.22 11.5 1.5 1.3 1 0 0 1 1 1 0 Chlorosome envelope protein C Ribosomal_S6e PF01092.19 KZN85666.1 - 1e-51 174.1 1.0 4e-50 169.0 0.0 2.6 2 1 0 2 2 2 1 Ribosomal protein S6e DUF3891 PF13030.6 KZN85667.1 - 0.033 14.0 0.1 0.042 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3891) HMG_box PF00505.19 KZN85668.1 - 1.7e-23 82.8 0.7 3e-23 82.0 0.7 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KZN85668.1 - 1.2e-09 38.6 0.3 2.5e-09 37.6 0.3 1.5 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 KZN85668.1 - 0.009 15.3 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box SNF2_N PF00176.23 KZN85669.1 - 5.8e-42 143.7 0.0 8e-35 120.2 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KZN85669.1 - 2.4e-08 34.3 0.0 4.6e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PRK PF00485.18 KZN85670.1 - 6.1e-06 26.1 0.0 8.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KZN85670.1 - 9.6e-06 26.2 0.0 4.8e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KZN85670.1 - 0.0024 18.4 0.0 0.004 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KZN85670.1 - 0.011 16.3 0.0 0.038 14.5 0.0 1.8 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 KZN85670.1 - 0.014 15.8 0.1 0.033 14.6 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 KZN85670.1 - 0.024 14.9 0.0 0.06 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 KZN85670.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.10 KZN85670.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 T2SSE PF00437.20 KZN85670.1 - 0.22 10.5 0.0 0.34 9.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Velvet PF11754.8 KZN85672.1 - 4e-43 148.2 7.0 2.2e-32 113.0 0.4 3.6 2 1 1 3 3 3 2 Velvet factor MOZ_SAS PF01853.18 KZN85673.1 - 2.9e-74 248.6 0.0 7.2e-74 247.3 0.0 1.6 2 0 0 2 2 2 1 MOZ/SAS family zf-MYST PF17772.1 KZN85673.1 - 8.9e-22 76.5 2.3 1.7e-21 75.5 2.3 1.4 1 0 0 1 1 1 1 MYST family zinc finger domain PHD_4 PF16866.5 KZN85673.1 - 2.9e-08 33.7 4.0 8.1e-08 32.2 4.0 1.8 1 0 0 1 1 1 1 PHD-finger OrfB_Zn_ribbon PF07282.11 KZN85673.1 - 0.6 10.1 5.4 14 5.7 3.6 3.0 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Prok-RING_1 PF14446.6 KZN85673.1 - 0.68 9.9 3.3 1.7 8.7 3.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.29 KZN85673.1 - 3.6 7.6 8.9 1.1 9.2 4.9 2.1 2 0 0 2 2 2 0 PHD-finger MWFE PF15879.5 KZN85674.1 - 2.6e-28 98.0 0.4 3.2e-28 97.7 0.4 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit Acetyltransf_2 PF00797.17 KZN85675.1 - 1.3e-34 120.1 0.0 1.7e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase RraA-like PF03737.15 KZN85676.1 - 8.5e-29 100.6 0.1 1.1e-28 100.2 0.1 1.2 1 0 0 1 1 1 1 Aldolase/RraA Thiolase_N PF00108.23 KZN85677.1 - 1.2e-72 244.4 4.2 1.2e-72 244.4 4.2 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KZN85677.1 - 5.7e-44 148.7 0.2 1.4e-43 147.5 0.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KZN85677.1 - 0.0022 17.6 3.4 0.0087 15.7 0.7 2.8 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KZN85677.1 - 0.03 14.2 0.5 10 6.1 0.1 2.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 KZN85677.1 - 0.083 13.1 0.0 0.26 11.5 0.0 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF218 PF02698.17 KZN85678.1 - 8.5e-09 35.5 0.0 1.3e-08 34.9 0.0 1.3 1 1 0 1 1 1 1 DUF218 domain Drf_GBD PF06371.13 KZN85680.1 - 4.3e-16 59.0 1.0 4.3e-16 59.0 1.0 2.8 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain Xpo1 PF08389.12 KZN85680.1 - 0.031 14.3 0.0 0.73 9.9 0.0 2.3 2 0 0 2 2 2 0 Exportin 1-like protein Nramp PF01566.18 KZN85681.1 - 1.3e-94 317.2 18.7 1.3e-94 317.2 18.7 1.9 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein Snf7 PF03357.21 KZN85682.1 - 2.6e-43 147.6 15.3 3.2e-43 147.3 15.3 1.0 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.12 KZN85682.1 - 0.00092 19.6 7.6 0.052 14.0 1.1 2.7 3 0 0 3 3 3 2 Nucleopolyhedrovirus P10 protein DUF4201 PF13870.6 KZN85682.1 - 0.0017 18.2 10.6 0.0024 17.6 7.5 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4201) DUF3584 PF12128.8 KZN85682.1 - 0.0028 15.3 5.3 0.0035 14.9 5.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) CLZ PF16526.5 KZN85682.1 - 0.0028 18.0 5.0 0.52 10.7 0.0 3.6 2 1 1 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Zwint PF15556.6 KZN85682.1 - 0.0043 16.6 6.9 0.0057 16.2 6.9 1.3 1 0 0 1 1 1 1 ZW10 interactor AF0941-like PF14591.6 KZN85682.1 - 0.022 15.3 3.8 0.033 14.8 3.8 1.3 1 0 0 1 1 1 0 AF0941-like DUF848 PF05852.11 KZN85682.1 - 0.051 13.7 7.4 0.024 14.7 4.7 1.8 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Prefoldin_2 PF01920.20 KZN85682.1 - 0.099 12.6 12.1 0.22 11.5 0.0 3.7 2 1 2 4 4 4 0 Prefoldin subunit DUF3523 PF12037.8 KZN85682.1 - 0.17 11.2 10.0 0.22 10.9 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) FlaC_arch PF05377.11 KZN85682.1 - 0.23 11.9 8.7 6.5 7.2 0.0 3.5 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) XhlA PF10779.9 KZN85682.1 - 0.38 11.0 6.6 4.1 7.7 0.0 3.4 2 1 1 3 3 3 0 Haemolysin XhlA DUF948 PF06103.11 KZN85682.1 - 0.94 9.8 3.2 1.1 9.5 0.9 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Glyco_hydro_26 PF02156.15 KZN85683.1 - 8.7e-71 238.9 1.8 1.1e-70 238.6 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 SAPS PF04499.15 KZN85684.1 - 7.6e-201 668.1 0.1 3.5e-199 662.7 0.0 2.6 3 0 0 3 3 3 1 SIT4 phosphatase-associated protein Mucin PF01456.17 KZN85684.1 - 6.2 6.8 7.6 17 5.4 7.6 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein SET PF00856.28 KZN85685.1 - 0.00015 22.2 0.0 0.00038 20.9 0.0 1.7 2 0 0 2 2 2 1 SET domain Complex1_51K PF01512.17 KZN85686.1 - 4e-46 156.6 0.0 6.4e-46 156.0 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KZN85686.1 - 4.5e-29 100.3 0.3 8.5e-29 99.5 0.3 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KZN85686.1 - 1.2e-08 34.7 0.0 3.7e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 SLBB domain DUF3568 PF12092.8 KZN85686.1 - 0.17 12.0 0.4 0.34 11.0 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) MFS_1 PF07690.16 KZN85687.1 - 7.2e-50 169.9 27.0 1.5e-48 165.6 19.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KZN85687.1 - 0.0045 15.5 4.0 0.0074 14.8 4.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KZN85687.1 - 1.3 7.2 9.0 0.29 9.4 2.7 2.5 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Nup96 PF12110.8 KZN85688.1 - 3.7e-82 275.7 2.6 5.9e-82 275.1 1.4 1.8 2 0 0 2 2 2 1 Nuclear protein 96 Nucleoporin2 PF04096.14 KZN85688.1 - 1.7e-50 171.0 0.0 2.7e-50 170.4 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KZN85688.1 - 9.5e-10 39.2 127.0 2.2e-06 28.4 36.8 10.6 4 3 5 9 9 9 3 Nucleoporin FG repeat region adh_short PF00106.25 KZN85689.1 - 9.2e-15 54.6 0.1 1.3e-14 54.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN85689.1 - 8.4e-10 38.6 0.2 1.3e-09 38.0 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN85689.1 - 8e-06 25.9 0.1 1.3e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KZN85689.1 - 0.027 15.1 0.1 0.068 13.8 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent HEM4 PF02602.15 KZN85689.1 - 0.028 13.8 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD 3HCDH_N PF02737.18 KZN85689.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AMP-binding PF00501.28 KZN85690.1 - 3.7e-89 299.3 0.1 4.7e-89 298.9 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KZN85690.1 - 1.7e-26 93.0 2.8 2.4e-26 92.5 0.4 2.4 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KZN85690.1 - 8.8e-17 60.8 0.5 2.2e-16 59.5 0.5 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus APH PF01636.23 KZN85691.1 - 2.3e-11 44.1 0.0 1.7e-10 41.2 0.0 2.3 1 1 0 2 2 2 1 Phosphotransferase enzyme family Peptidase_M20 PF01546.28 KZN85692.1 - 7.1e-35 120.6 0.0 1.1e-34 119.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 KZN85692.1 - 2.3e-05 24.2 0.0 0.00014 21.6 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M28 M20_dimer PF07687.14 KZN85692.1 - 0.00072 19.4 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain PALP PF00291.25 KZN85693.1 - 8.2e-62 209.3 0.6 8.2e-62 209.3 0.6 2.0 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.28 KZN85693.1 - 1.2e-27 97.0 0.2 2.7e-27 95.8 0.2 1.7 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KZN85693.1 - 9.1e-19 67.4 0.0 2.6e-18 65.9 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KZN85693.1 - 0.00055 19.7 0.1 0.0011 18.6 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M28 LpxI_N PF17930.1 KZN85693.1 - 0.04 13.8 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 LpxI N-terminal domain GET2 PF08690.10 KZN85694.1 - 6.5e-15 55.6 8.0 5e-14 52.7 8.0 1.9 1 1 0 1 1 1 1 GET complex subunit GET2 PepSY_TM PF03929.16 KZN85694.1 - 0.024 14.3 3.0 0.033 13.9 0.1 2.2 2 0 0 2 2 2 0 PepSY-associated TM region TctB PF07331.11 KZN85694.1 - 0.05 13.9 1.8 0.085 13.1 1.8 1.4 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family TetR_C_33 PF13305.6 KZN85694.1 - 0.67 10.7 3.9 2.3 9.0 0.2 2.7 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Homeobox_KN PF05920.11 KZN85695.1 - 1.7e-16 59.9 1.6 1.7e-16 59.9 1.6 1.9 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 KZN85695.1 - 2.8e-07 30.3 3.3 6e-07 29.2 3.3 1.6 1 0 0 1 1 1 1 Homeodomain zf-C2H2 PF00096.26 KZN85695.1 - 0.0062 16.9 30.4 0.027 14.9 3.5 5.3 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KZN85695.1 - 0.0064 17.2 3.8 0.0064 17.2 3.8 5.8 6 0 0 6 6 6 2 C2H2-type zinc finger zf-met PF12874.7 KZN85695.1 - 0.16 12.4 12.5 1.2 9.7 0.0 5.1 5 0 0 5 5 5 0 Zinc-finger of C2H2 type FANCL_C PF11793.8 KZN85695.1 - 0.39 10.9 3.3 1.4 9.1 2.3 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain Zn_clus PF00172.18 KZN85695.1 - 1.6 8.9 12.4 0.068 13.3 5.7 2.1 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Aa_trans PF01490.18 KZN85696.1 - 1.7e-40 139.0 29.4 2.1e-40 138.7 29.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.6 KZN85696.1 - 0.23 11.3 4.7 4.1 7.3 0.1 3.2 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase SID-1_RNA_chan PF13965.6 KZN85696.1 - 0.51 8.7 9.9 0.81 8.0 9.9 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 NAD_binding_10 PF13460.6 KZN85697.1 - 3.6e-16 59.6 0.0 4.5e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KZN85697.1 - 0.12 11.9 0.2 0.25 10.8 0.1 1.6 1 1 1 2 2 2 0 short chain dehydrogenase Fungal_trans PF04082.18 KZN85698.1 - 9.6e-14 51.0 0.0 1.6e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN85698.1 - 4.6e-09 36.2 12.4 7.9e-09 35.5 12.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Octopine_DH PF02317.17 KZN85699.1 - 2e-44 151.3 0.0 3.2e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain NAD_Gly3P_dh_N PF01210.23 KZN85699.1 - 3.7e-07 30.3 0.0 7.9e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_8 PF13450.6 KZN85699.1 - 0.00033 20.8 0.1 0.00068 19.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KZN85699.1 - 0.0025 17.1 0.0 0.0038 16.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KZN85699.1 - 0.0037 16.4 0.1 0.0069 15.5 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A ApbA PF02558.16 KZN85699.1 - 0.0056 16.3 0.0 0.013 15.1 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 KZN85699.1 - 0.013 16.0 0.0 0.04 14.5 0.0 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_3 PF01494.19 KZN85699.1 - 0.021 14.1 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 KZN85699.1 - 0.023 13.8 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KZN85699.1 - 0.03 13.0 0.0 0.043 12.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KZN85699.1 - 0.05 14.2 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KZN85699.1 - 0.077 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KZN85699.1 - 0.17 11.1 0.2 0.33 10.2 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 KZN85700.1 - 6.3e-57 193.1 11.5 6.3e-57 193.1 11.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN85700.1 - 1.1e-13 50.9 10.0 1.1e-13 50.9 10.0 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_5 PF05631.14 KZN85700.1 - 6e-07 28.7 5.2 2e-05 23.7 1.7 2.2 2 0 0 2 2 2 2 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 KZN85700.1 - 3.8e-05 22.7 4.7 0.062 12.1 6.9 2.8 2 1 0 2 2 2 2 MFS_1 like family TRI12 PF06609.13 KZN85700.1 - 0.00012 20.7 4.2 0.0002 19.9 4.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) NUDIX PF00293.28 KZN85701.1 - 9.8e-10 38.6 0.1 3e-09 37.0 0.1 1.7 1 1 0 1 1 1 1 NUDIX domain TrkH PF02386.16 KZN85704.1 - 2.8e-15 55.8 0.2 6.9e-12 44.6 0.0 2.1 2 0 0 2 2 2 2 Cation transport protein DUF3333 PF11812.8 KZN85704.1 - 0.12 12.5 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) DUF2207 PF09972.9 KZN85704.1 - 0.14 10.9 1.0 0.67 8.7 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) LapA_dom PF06305.11 KZN85704.1 - 0.82 9.5 5.3 14 5.6 2.3 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain TrkH PF02386.16 KZN85705.1 - 4.7e-09 35.2 0.1 5e-09 35.1 0.1 1.0 1 0 0 1 1 1 1 Cation transport protein Alk_phosphatase PF00245.20 KZN85706.1 - 1.8e-69 234.7 0.3 3.6e-69 233.7 0.3 1.5 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 KZN85706.1 - 1e-07 31.6 4.1 2.1e-06 27.3 4.0 2.3 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KZN85706.1 - 1.8e-05 24.5 0.5 3.2e-05 23.7 0.5 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KZN85706.1 - 0.00042 19.0 0.2 0.00069 18.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 KZN85706.1 - 0.008 15.6 0.5 0.015 14.7 0.5 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily FabA PF07977.13 KZN85707.1 - 0.065 12.9 0.1 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 FabA-like domain Zn_clus PF00172.18 KZN85708.1 - 0.0001 22.3 8.7 0.00017 21.7 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YihI PF04220.12 KZN85708.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Der GTPase activator (YihI) zf-ribbon_3 PF13248.6 KZN85708.1 - 3.7 7.1 6.6 36 4.0 6.6 2.2 1 1 0 1 1 1 0 zinc-ribbon domain Fungal_trans PF04082.18 KZN85709.1 - 1.7e-17 63.3 0.9 3.8e-17 62.2 0.9 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN85709.1 - 1.2e-07 31.7 12.5 1.2e-07 31.7 12.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TTRAP PF14203.6 KZN85709.1 - 0.063 13.3 0.0 0.24 11.4 0.0 2.0 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein C2 PF00168.30 KZN85710.1 - 8.7e-30 103.1 0.0 9.1e-17 61.2 0.0 2.5 2 0 0 2 2 2 2 C2 domain BSP_II PF05432.11 KZN85710.1 - 7.7 6.1 14.2 0.085 12.5 1.2 2.5 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) IMS PF00817.20 KZN85712.1 - 8.3e-38 129.7 0.0 1.6e-37 128.8 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KZN85712.1 - 4.2e-18 66.1 0.1 1.1e-17 64.8 0.1 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KZN85712.1 - 1e-05 25.5 0.0 0.00024 21.3 0.0 2.6 2 0 0 2 2 2 1 IMS family HHH motif HHH_5 PF14520.6 KZN85712.1 - 0.0013 19.3 0.0 0.0038 17.8 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_8 PF14716.6 KZN85712.1 - 0.037 14.4 0.0 0.4 11.1 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain Reprolysin_5 PF13688.6 KZN85713.1 - 7.9e-60 202.4 9.0 7.9e-60 202.4 9.0 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KZN85713.1 - 9.9e-49 165.7 4.2 2.4e-48 164.5 4.2 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KZN85713.1 - 2.4e-41 141.8 4.6 2.4e-41 141.8 4.6 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 KZN85713.1 - 3.3e-17 63.1 34.9 3.3e-17 63.1 34.9 4.5 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 KZN85713.1 - 4.2e-08 33.7 0.5 2.4e-07 31.3 0.0 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 KZN85713.1 - 0.00022 21.5 0.0 0.00044 20.5 0.0 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide Mid2 PF04478.12 KZN85713.1 - 0.0016 18.3 0.4 0.0047 16.8 0.2 1.9 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor ADAM_CR_2 PF17771.1 KZN85713.1 - 0.013 16.1 11.3 0.013 16.1 11.3 5.1 1 1 1 3 3 3 0 ADAM cysteine-rich domain LapA_dom PF06305.11 KZN85713.1 - 0.075 12.9 0.6 0.29 11.0 0.1 2.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain EF-hand_1 PF00036.32 KZN85714.1 - 3.9e-14 51.1 2.1 1.7e-05 24.0 0.1 3.6 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 KZN85714.1 - 1e-13 51.5 2.1 6.8e-08 32.9 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KZN85714.1 - 1.8e-12 46.1 4.3 1.7e-05 24.3 0.2 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 KZN85714.1 - 1.1e-10 41.2 2.1 5.8e-08 32.5 0.1 2.7 2 1 1 3 3 3 2 EF-hand domain pair DUF3572 PF12096.8 KZN85714.1 - 0.026 14.7 0.1 1.1 9.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3572) EF-hand_4 PF12763.7 KZN85714.1 - 0.053 13.5 0.0 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 KZN85714.1 - 1.9 8.1 6.9 6.9 6.4 0.1 3.1 3 0 0 3 3 3 0 EF hand Zn_clus PF00172.18 KZN85715.1 - 1.5 9.0 8.3 2.9 8.1 8.3 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MgsA_C PF12002.8 KZN85716.1 - 2.5e-56 190.2 0.0 4.4e-56 189.4 0.0 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KZN85716.1 - 6.8e-23 80.8 2.1 1.2e-22 80.1 0.9 2.0 2 0 0 2 2 2 1 AAA C-terminal domain AAA PF00004.29 KZN85716.1 - 1.6e-13 51.2 0.0 3.8e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KZN85716.1 - 1.4e-09 37.9 0.0 2.8e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KZN85716.1 - 1.8e-05 24.3 0.1 0.16 11.4 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KZN85716.1 - 6.2e-05 23.0 0.0 0.0011 18.9 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KZN85716.1 - 6.5e-05 22.7 0.0 0.0036 17.0 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 KZN85716.1 - 0.00014 22.2 0.4 0.05 14.0 0.1 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_3 PF07726.11 KZN85716.1 - 0.00096 19.0 0.0 0.0025 17.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KZN85716.1 - 0.001 19.4 0.1 0.0039 17.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KZN85716.1 - 0.0049 16.1 0.0 0.008 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 KZN85716.1 - 0.007 16.4 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KZN85716.1 - 0.0085 16.1 0.1 2.2 8.3 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KZN85716.1 - 0.017 14.9 0.1 0.037 13.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 KZN85716.1 - 0.02 14.1 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Sigma54_activ_2 PF14532.6 KZN85716.1 - 0.023 14.8 0.0 0.049 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain PIF1 PF05970.14 KZN85716.1 - 0.056 12.6 0.1 0.087 12.0 0.1 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_29 PF13555.6 KZN85716.1 - 0.063 13.0 0.0 3.8 7.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain TsaE PF02367.17 KZN85716.1 - 0.076 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KZN85716.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KZN85716.1 - 0.15 12.4 0.2 0.38 11.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KZN85716.1 - 0.15 12.6 0.0 0.33 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 KZN85716.1 - 0.16 12.1 0.1 0.31 11.2 0.1 1.4 1 0 0 1 1 1 0 Shikimate kinase NB-ARC PF00931.22 KZN85716.1 - 0.19 10.9 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_13 PF13166.6 KZN85716.1 - 0.31 9.6 0.1 0.61 8.7 0.0 1.4 2 0 0 2 2 2 0 AAA domain Aminotran_1_2 PF00155.21 KZN85717.1 - 2.5e-58 198.0 0.0 3.6e-56 190.9 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II zf-MYND PF01753.18 KZN85718.1 - 0.97 9.6 6.1 3.1 8.0 6.1 1.9 1 0 0 1 1 1 0 MYND finger SR-25 PF10500.9 KZN85718.1 - 3.2 7.3 46.3 0.024 14.2 11.3 3.4 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Dynamin_M PF01031.20 KZN85719.1 - 0.0052 16.0 0.0 2.9 7.0 0.0 2.5 3 0 0 3 3 3 2 Dynamin central region Baculo_PEP_C PF04513.12 KZN85719.1 - 0.039 14.0 4.4 0.71 9.9 0.7 2.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 KZN85719.1 - 2.4 8.3 5.3 3 7.9 1.4 2.7 3 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) ETRAMP PF09716.10 KZN85719.1 - 6.2 7.0 5.8 42 4.3 0.2 3.9 4 0 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) DUF2706 PF10913.8 KZN85719.1 - 8.1 6.4 6.2 15 5.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2706) Ald_Xan_dh_C2 PF02738.18 KZN85720.1 - 3.7e-199 662.8 1.5 5.3e-199 662.2 1.5 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KZN85720.1 - 4.3e-49 166.5 0.0 1e-48 165.3 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 KZN85720.1 - 8.3e-33 113.0 0.0 1.9e-32 111.9 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 KZN85720.1 - 1.1e-31 109.0 2.0 1.7e-31 108.4 0.1 2.4 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 KZN85720.1 - 3e-29 100.9 0.0 6.3e-29 99.8 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 KZN85720.1 - 4.7e-07 29.7 2.4 5e-07 29.6 0.2 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_4 PF07993.12 KZN85722.1 - 2e-73 246.8 0.0 2.9e-73 246.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KZN85722.1 - 1.1e-66 225.2 0.0 1.9e-66 224.4 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KZN85722.1 - 2.6e-11 43.4 0.0 7.4e-11 42.0 0.0 1.8 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Condensation PF00668.20 KZN85722.1 - 1.6e-09 37.0 0.0 1.4e-08 33.9 0.0 2.0 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KZN85722.1 - 1.1e-06 28.9 0.0 2.8e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KZN85722.1 - 1.4e-05 24.3 0.0 3.4e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 KZN85722.1 - 4.3e-05 24.4 0.0 0.00053 20.9 0.0 2.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain RmlD_sub_bind PF04321.17 KZN85722.1 - 0.0022 17.2 0.0 0.062 12.4 0.0 2.4 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KZN85722.1 - 0.0054 16.6 0.1 0.059 13.3 0.1 2.5 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KZN85722.1 - 0.0095 15.1 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KZN85722.1 - 0.035 13.5 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Pro_CA PF00484.19 KZN85723.1 - 6.4e-44 150.0 0.0 8.8e-44 149.5 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase AAA PF00004.29 KZN85724.1 - 1.9e-18 67.2 0.0 5e-18 65.8 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KZN85724.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NB-ARC PF00931.22 KZN85724.1 - 0.024 13.9 0.0 0.33 10.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_16 PF13191.6 KZN85724.1 - 0.025 15.0 0.4 0.17 12.2 0.4 2.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KZN85724.1 - 0.029 14.4 0.0 0.075 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KZN85724.1 - 0.043 14.1 0.4 0.63 10.3 0.4 2.4 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KZN85724.1 - 0.051 14.0 0.2 0.2 12.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 KZN85724.1 - 0.16 12.0 0.2 0.79 9.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) Ank_2 PF12796.7 KZN85725.1 - 1.2e-38 131.5 3.6 1e-14 54.9 0.1 3.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 KZN85725.1 - 2.9e-34 116.0 4.5 3.5e-10 39.8 0.0 7.2 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 KZN85725.1 - 6.5e-33 112.7 4.7 5.7e-09 36.3 0.0 5.1 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN85725.1 - 9.5e-30 99.3 0.6 4.6e-07 29.6 0.0 7.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KZN85725.1 - 1.6e-20 72.9 3.3 1.5e-06 28.3 0.0 5.3 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Helo_like_N PF17111.5 KZN85726.1 - 0.037 13.4 0.5 0.068 12.5 0.5 1.5 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Baculo_PEP_C PF04513.12 KZN85726.1 - 0.062 13.3 0.2 0.077 13.0 0.2 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sulfatase PF00884.23 KZN85727.1 - 8.7e-15 54.9 0.1 1.3e-14 54.3 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KZN85727.1 - 4.8e-06 26.4 0.1 6.2e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.12 KZN85727.1 - 0.0092 15.1 0.4 0.018 14.1 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) DUF229 PF02995.17 KZN85727.1 - 0.012 14.3 0.1 0.022 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Arylsulfotran_2 PF14269.6 KZN85728.1 - 2.6e-43 148.5 1.3 3.9e-43 147.9 1.3 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KZN85728.1 - 3.6e-12 45.9 2.7 1.7e-10 40.4 2.7 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Fungal_trans PF04082.18 KZN85729.1 - 3.9e-17 62.2 2.2 3.9e-17 62.2 2.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN85729.1 - 0.00016 21.7 10.0 0.00027 21.0 10.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MukF_M PF17192.4 KZN85730.1 - 0.015 15.1 0.0 0.031 14.0 0.0 1.5 1 1 1 2 2 2 0 MukF middle domain Oxidored_FMN PF00724.20 KZN85732.1 - 3.4e-71 240.3 0.0 4.7e-71 239.8 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1848 PF08902.11 KZN85732.1 - 0.087 12.5 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Fungal_trans_2 PF11951.8 KZN85733.1 - 1.2e-05 24.4 0.2 1.8e-05 23.7 0.2 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN85733.1 - 0.00087 19.4 4.6 0.0018 18.3 4.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1422 PF07226.11 KZN85733.1 - 0.0081 16.2 0.1 0.014 15.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1422) FMO-like PF00743.19 KZN85735.1 - 2.5e-13 49.3 0.1 4.6e-10 38.5 0.1 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KZN85735.1 - 4.4e-13 49.1 0.0 3.2e-09 36.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN85735.1 - 9.7e-11 41.7 0.0 3.4e-10 40.0 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KZN85735.1 - 4.2e-08 32.8 0.1 0.0001 21.7 0.1 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KZN85735.1 - 2e-05 23.9 0.1 0.039 13.1 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KZN85735.1 - 0.00031 20.7 0.5 0.0072 16.3 0.0 3.2 4 1 0 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KZN85735.1 - 0.00056 19.1 0.0 0.00096 18.3 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 KZN85735.1 - 0.0013 19.2 0.0 1.5 9.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KZN85735.1 - 0.042 13.1 0.4 0.44 9.8 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KZN85735.1 - 0.068 12.7 0.0 0.19 11.2 0.0 1.8 1 0 0 1 1 1 0 FAD dependent oxidoreductase Aldo_ket_red PF00248.21 KZN85736.1 - 1.1e-69 234.9 0.0 1.2e-69 234.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Mannosyl_trans2 PF04188.13 KZN85738.1 - 3.1e-54 185.0 12.9 1.8e-52 179.2 12.9 2.0 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) BLM10_mid PF16507.5 KZN85739.1 - 6e-206 685.2 0.0 1.1e-205 684.3 0.0 1.5 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KZN85739.1 - 1.9e-29 101.4 0.0 1.2e-28 98.9 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 KZN85739.1 - 2.2e-20 72.7 0.0 6e-20 71.3 0.0 1.8 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal CLASP_N PF12348.8 KZN85739.1 - 5.2e-05 22.9 0.0 0.14 11.7 0.0 2.8 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 KZN85739.1 - 0.016 15.4 0.0 2.1 8.8 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat Pkinase PF00069.25 KZN85740.1 - 4.5e-28 98.3 0.0 1.5e-26 93.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN85740.1 - 3.4e-06 26.6 0.0 0.049 12.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KZN85740.1 - 0.0083 16.1 0.1 0.032 14.2 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF3405 PF11885.8 KZN85741.1 - 4.4e-172 573.3 1.1 7e-172 572.6 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) SHR-BD PF06650.12 KZN85742.1 - 1.8e-97 325.9 0.0 3e-96 321.9 0.0 2.8 2 1 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 KZN85742.1 - 1.3e-93 312.8 10.5 5.7e-88 294.3 0.3 5.4 4 1 1 5 5 5 3 Repeating coiled region of VPS13 VPS13 PF16908.5 KZN85742.1 - 1.4e-77 260.7 0.0 9e-76 254.8 0.0 3.6 4 0 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KZN85742.1 - 3.4e-74 248.5 4.1 7e-69 231.1 0.4 2.9 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 KZN85742.1 - 1.6e-39 134.6 0.0 5.3e-39 132.9 0.0 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 KZN85742.1 - 5.9e-07 29.7 0.0 2.5e-06 27.7 0.0 2.1 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain DUF3429 PF11911.8 KZN85743.1 - 4.6e-43 146.9 12.6 6.6e-43 146.5 12.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) FGGY_C PF02782.16 KZN85744.1 - 4.7e-72 241.9 1.7 7.6e-72 241.2 1.7 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KZN85744.1 - 1.6e-62 211.3 0.0 2.1e-62 210.9 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KZN85744.1 - 0.007 15.9 0.4 1 8.8 0.0 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Peptidase_M41 PF01434.18 KZN85745.1 - 3.8e-57 193.2 0.6 7.3e-57 192.3 0.6 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KZN85745.1 - 8.6e-43 145.9 0.0 3e-42 144.2 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KZN85745.1 - 2.1e-09 37.0 0.0 6.9e-09 35.4 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KZN85745.1 - 1.5e-05 25.0 0.0 4.7e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KZN85745.1 - 2.9e-05 24.5 0.7 0.00041 20.8 0.7 3.0 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 KZN85745.1 - 0.00014 21.2 1.5 0.00016 21.0 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_22 PF13401.6 KZN85745.1 - 0.00033 20.9 0.1 0.033 14.5 0.1 2.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KZN85745.1 - 0.00088 19.0 0.0 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KZN85745.1 - 0.0042 17.2 0.0 0.014 15.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KZN85745.1 - 0.0049 16.5 1.1 0.88 9.1 0.3 2.6 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KZN85745.1 - 0.014 15.2 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 KZN85745.1 - 0.021 15.4 0.2 0.16 12.5 0.0 2.7 4 0 0 4 4 3 0 AAA domain AAA_2 PF07724.14 KZN85745.1 - 0.022 14.9 0.0 0.096 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 KZN85745.1 - 0.024 14.0 0.1 0.049 13.0 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KZN85745.1 - 0.073 12.4 0.6 1.4 8.2 0.0 2.6 3 0 0 3 3 3 0 KaiC AAA_28 PF13521.6 KZN85745.1 - 0.11 12.8 0.4 0.25 11.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 KZN85745.1 - 0.13 11.8 0.1 0.46 10.0 0.1 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 KZN85745.1 - 0.16 11.9 0.3 1.9 8.4 0.1 2.4 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 KZN85745.1 - 0.26 10.6 3.2 0.73 9.1 0.4 2.7 2 1 1 3 3 3 0 Zeta toxin NTP_transferase PF00483.23 KZN85747.1 - 1.7e-53 181.7 0.0 3.3e-53 180.8 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 KZN85747.1 - 1.5e-14 53.0 11.5 4.1e-11 42.2 4.3 4.1 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KZN85747.1 - 7e-10 39.5 0.0 1.1e-09 38.9 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KZN85747.1 - 3.9e-06 26.5 2.9 3.9e-06 26.5 2.9 3.1 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KZN85747.1 - 0.0061 14.8 0.4 0.0089 14.2 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) IspD PF01128.19 KZN85747.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase adh_short PF00106.25 KZN85748.1 - 3.8e-11 42.8 0.0 6.8e-06 25.7 0.0 2.9 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KZN85748.1 - 0.012 15.2 0.0 2.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN85748.1 - 0.022 14.7 0.0 0.062 13.2 0.0 1.7 2 0 0 2 2 2 0 KR domain Metal_resist PF13801.6 KZN85748.1 - 0.14 12.3 0.3 0.14 12.3 0.3 1.9 2 0 0 2 2 2 0 Heavy-metal resistance NYD-SP28 PF14772.6 KZN85748.1 - 5.2 7.2 9.5 2 8.5 6.8 1.7 2 0 0 2 2 2 0 Sperm tail Suc_Fer-like PF06999.12 KZN85749.1 - 1.1e-69 234.3 0.0 1.5e-69 233.8 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like zf-C2H2 PF00096.26 KZN85750.1 - 1.6e-17 62.9 40.1 3.5e-05 24.0 5.0 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KZN85750.1 - 6.5e-15 54.8 29.1 3.1e-05 24.2 0.7 4.7 4 1 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KZN85750.1 - 6.4e-06 26.6 36.0 0.089 13.7 3.8 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KZN85750.1 - 0.11 12.8 13.4 0.73 10.2 1.3 3.3 1 1 1 2 2 2 0 C2H2-type zinc ribbon TFIIA PF03153.13 KZN85750.1 - 0.83 9.6 20.4 0.97 9.4 20.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Aminotran_1_2 PF00155.21 KZN85751.1 - 9.8e-34 117.1 0.0 1.3e-33 116.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II PH_10 PF15411.6 KZN85752.1 - 1.2e-40 138.5 0.0 2.9e-40 137.3 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 KZN85752.1 - 8.5e-34 115.7 0.0 1.7e-33 114.7 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.20 KZN85752.1 - 3.3e-26 92.7 3.0 5.8e-26 91.8 3.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 KZN85752.1 - 1.9e-08 34.1 0.1 4.6e-08 32.9 0.1 1.6 1 0 0 1 1 1 1 PB1 domain WD40 PF00400.32 KZN85753.1 - 1.5e-28 98.5 16.8 3.6e-05 24.4 0.0 7.6 7 0 0 7 7 7 5 WD domain, G-beta repeat F-box-like PF12937.7 KZN85753.1 - 2.1e-10 40.3 1.4 5.1e-10 39.1 1.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN85753.1 - 1.5e-07 31.1 0.3 3e-07 30.2 0.3 1.5 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KZN85753.1 - 1.9e-05 24.9 0.7 0.012 15.9 0.1 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KZN85753.1 - 0.00012 20.9 1.9 1.3 7.6 0.2 3.4 3 0 0 3 3 3 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KZN85753.1 - 0.013 14.8 0.0 0.57 9.5 0.0 2.7 3 0 0 3 3 3 0 WD40-like domain GST_C_2 PF13410.6 KZN85754.1 - 5.5e-08 32.7 1.2 1.3e-07 31.5 1.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KZN85754.1 - 1.1e-07 32.0 0.1 3.2e-07 30.6 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KZN85754.1 - 2.1e-06 28.0 0.0 4.4e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KZN85754.1 - 0.0032 17.6 0.1 0.0092 16.2 0.1 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KZN85754.1 - 0.028 14.8 0.0 0.051 13.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 KZN85754.1 - 0.035 14.4 0.0 0.053 13.8 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Pectate_lyase PF03211.13 KZN85755.1 - 1.7e-77 259.6 6.5 2.1e-77 259.3 6.5 1.1 1 0 0 1 1 1 1 Pectate lyase Uds1 PF15456.6 KZN85756.1 - 8.3e-45 152.1 0.3 8.3e-45 152.1 0.3 8.0 4 2 2 6 6 6 1 Up-regulated During Septation DUF1192 PF06698.11 KZN85756.1 - 0.46 10.6 0.0 0.46 10.6 0.0 7.7 9 1 0 9 9 9 0 Protein of unknown function (DUF1192) DUF4407 PF14362.6 KZN85756.1 - 0.99 8.7 88.3 3 7.1 16.1 6.0 2 1 3 5 5 5 0 Domain of unknown function (DUF4407) HsbA PF12296.8 KZN85756.1 - 2.2 8.7 18.6 15 6.1 0.4 5.4 2 1 2 5 5 5 0 Hydrophobic surface binding protein A MFS_1 PF07690.16 KZN85757.1 - 3.7e-26 91.9 49.2 5.4e-25 88.1 30.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KZN85757.1 - 0.0068 15.3 1.4 0.0068 15.3 1.4 2.5 1 1 2 3 3 3 1 MFS_1 like family UCR_hinge PF02320.16 KZN85758.1 - 1.7e-27 95.4 9.5 1.7e-27 95.4 9.5 1.8 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein PRCC PF10253.9 KZN85758.1 - 0.43 11.3 20.5 0.53 11.0 20.5 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF4045 PF13254.6 KZN85758.1 - 0.51 9.9 23.3 0.63 9.6 23.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF1631 PF07793.11 KZN85758.1 - 0.7 8.2 11.9 0.82 8.0 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Presenilin PF01080.17 KZN85758.1 - 0.8 8.4 16.5 0.89 8.2 16.5 1.1 1 0 0 1 1 1 0 Presenilin CAML PF14963.6 KZN85758.1 - 0.97 9.5 6.3 1.2 9.3 6.3 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand CDC27 PF09507.10 KZN85758.1 - 3.7 6.8 26.7 4.3 6.6 26.7 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Mitofilin PF09731.9 KZN85758.1 - 4.1 6.1 23.5 4.8 5.9 23.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SAPS PF04499.15 KZN85758.1 - 4.6 5.9 13.7 4.8 5.9 13.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 KZN85758.1 - 6.5 6.0 24.9 7.6 5.8 24.9 1.1 1 0 0 1 1 1 0 BUD22 LAP1C PF05609.12 KZN85758.1 - 6.8 5.7 17.3 7.9 5.4 17.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Apt1 PF10351.9 KZN85758.1 - 7.5 5.3 8.2 8.1 5.2 8.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PA26 PF04636.13 KZN85758.1 - 9.2 5.1 11.9 11 4.8 11.9 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) XRN_M PF17846.1 KZN85758.1 - 9.4 5.1 9.0 11 4.9 9.0 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Vps36_ESCRT-II PF11605.8 KZN85759.1 - 0.0014 18.7 0.0 0.18 12.0 0.0 2.2 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 Acyltransferase PF01553.21 KZN85760.1 - 5.1e-09 35.9 0.0 1.1e-07 31.5 0.0 2.4 1 1 0 1 1 1 1 Acyltransferase Prenyltransf PF01255.19 KZN85761.1 - 2.2e-80 269.4 0.0 3.8e-80 268.6 0.0 1.4 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Sacchrp_dh_C PF16653.5 KZN85762.1 - 1.4e-73 248.3 0.0 2.3e-71 241.0 0.0 2.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KZN85762.1 - 8.4e-27 94.0 0.7 1.4e-26 93.3 0.7 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KZN85762.1 - 6.9e-09 35.9 0.4 1.4e-08 34.8 0.4 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KZN85762.1 - 8.8e-07 29.0 0.4 4.7e-06 26.6 0.2 2.0 2 0 0 2 2 2 1 NAD(P)H-binding IlvN PF07991.12 KZN85762.1 - 0.00047 19.8 0.3 0.0078 15.8 0.1 2.4 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NmrA PF05368.13 KZN85762.1 - 0.00049 19.7 0.5 0.00076 19.1 0.5 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KZN85762.1 - 0.00057 19.0 0.1 0.00093 18.3 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 KZN85762.1 - 0.0038 17.8 0.2 0.0085 16.7 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 KZN85762.1 - 0.018 14.4 0.7 0.027 13.7 0.7 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KZN85762.1 - 0.034 14.6 0.3 0.079 13.4 0.3 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Aha1_N PF09229.11 KZN85763.1 - 9.5e-40 136.0 2.3 2.1e-39 134.9 1.0 2.0 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KZN85763.1 - 1.1e-19 70.8 0.5 2.4e-19 69.8 0.5 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein MFS_1 PF07690.16 KZN85765.1 - 2.5e-40 138.5 43.7 8.7e-33 113.7 22.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KZN85765.1 - 1.6e-06 27.2 1.7 1.6e-06 27.2 1.7 2.7 1 1 0 2 2 2 1 MFS_1 like family FBPase PF00316.20 KZN85766.1 - 6.3e-67 224.7 0.0 1.1e-66 223.9 0.0 1.4 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain V_ATPase_I PF01496.19 KZN85767.1 - 0 1077.8 0.0 0 1077.6 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CheZ PF04344.13 KZN85767.1 - 0.018 15.0 1.7 0.13 12.1 0.1 2.4 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ DUF1515 PF07439.11 KZN85767.1 - 0.033 14.2 0.1 0.091 12.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DASH_Dam1 PF08653.10 KZN85767.1 - 0.11 12.3 0.8 9.2 6.2 0.0 3.7 4 0 0 4 4 4 0 DASH complex subunit Dam1 DUF1664 PF07889.12 KZN85767.1 - 0.37 10.8 1.3 14 5.7 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Filament PF00038.21 KZN85767.1 - 0.84 9.2 4.2 22 4.5 1.6 2.4 2 1 0 2 2 2 0 Intermediate filament protein Tektin PF03148.14 KZN85767.1 - 3.6 6.3 7.1 6.3 5.4 0.5 2.8 2 1 1 3 3 3 0 Tektin family PH_6 PF15406.6 KZN85770.1 - 3.5e-37 127.1 4.1 3.5e-37 127.1 4.1 4.4 2 1 2 4 4 4 1 Pleckstrin homology domain PH PF00169.29 KZN85770.1 - 1e-07 32.4 0.0 5.5e-07 30.0 0.0 2.3 1 1 0 1 1 1 1 PH domain PH_4 PF15404.6 KZN85770.1 - 0.26 11.1 0.0 0.26 11.1 0.0 3.9 2 1 0 2 2 2 0 Pleckstrin homology domain bZIP_2 PF07716.15 KZN85771.1 - 0.00026 21.0 9.8 0.0005 20.1 9.8 1.5 1 0 0 1 1 1 1 Basic region leucine zipper PKcGMP_CC PF16808.5 KZN85771.1 - 0.00047 19.9 4.0 0.00088 19.1 4.0 1.3 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase bZIP_1 PF00170.21 KZN85771.1 - 0.024 14.7 7.4 0.048 13.8 7.4 1.4 1 0 0 1 1 1 0 bZIP transcription factor XLF PF09302.11 KZN85771.1 - 0.04 14.1 0.8 0.069 13.3 0.8 1.3 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component DUF641 PF04859.12 KZN85771.1 - 0.056 13.8 1.7 0.097 13.0 1.7 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) SlyX PF04102.12 KZN85771.1 - 0.085 13.5 2.3 0.2 12.3 2.3 1.6 1 0 0 1 1 1 0 SlyX LPD23 PF18838.1 KZN85771.1 - 0.21 11.4 0.9 0.4 10.5 0.9 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 23 Asn_synthase PF00733.21 KZN85772.1 - 1.2e-13 51.5 0.4 8.2e-06 25.7 0.0 3.1 2 1 1 3 3 3 2 Asparagine synthase GATase_7 PF13537.6 KZN85772.1 - 3.2e-06 27.1 0.0 1.6e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KZN85772.1 - 0.0002 20.9 0.0 0.00034 20.1 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_6 PF13522.6 KZN85772.1 - 0.007 16.6 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain VPS9 PF02204.18 KZN85773.1 - 3.4e-30 104.3 0.0 6.7e-30 103.4 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KZN85773.1 - 1.1e-14 54.4 0.7 2.8e-14 53.2 0.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 KZN85773.1 - 1.3e-09 37.6 0.3 1.5e-08 34.1 0.0 2.3 2 0 0 2 2 2 1 CUE domain Abhydrolase_6 PF12697.7 KZN85774.1 - 1e-11 45.9 1.0 1.7e-11 45.1 0.4 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KZN85774.1 - 3.8e-07 29.6 0.0 6e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KZN85774.1 - 6.9e-05 22.6 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 KZN85774.1 - 0.0088 15.8 0.0 0.053 13.2 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein Ceramidase PF05875.12 KZN85775.1 - 9.6e-104 346.5 12.9 1.1e-103 346.2 12.9 1.0 1 0 0 1 1 1 1 Ceramidase Peptidase_U4 PF03419.13 KZN85775.1 - 0.018 14.3 7.0 0.52 9.5 0.5 2.1 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Mito_carr PF00153.27 KZN85776.1 - 2.9e-53 177.8 2.5 1.2e-18 66.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF5333 PF17267.2 KZN85777.1 - 0.0041 17.3 7.8 0.011 15.9 7.0 2.3 1 1 0 1 1 1 1 Family of unknown function (DUF5333) Prefoldin_2 PF01920.20 KZN85778.1 - 3.1e-18 65.7 7.0 3.8e-18 65.4 7.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit T6PP_N PF18572.1 KZN85778.1 - 0.32 10.9 5.5 1 9.2 5.5 1.8 1 1 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain SlyX PF04102.12 KZN85778.1 - 6.6 7.4 8.3 8.7 7.0 3.6 2.2 2 0 0 2 2 2 0 SlyX HMG_box PF00505.19 KZN85779.1 - 2e-13 50.5 0.3 3.9e-13 49.6 0.3 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KZN85779.1 - 0.00025 21.6 1.2 0.00025 21.6 1.2 1.9 2 0 0 2 2 2 1 HMG-box domain MATalpha_HMGbox PF04769.12 KZN85779.1 - 0.063 12.6 0.1 0.097 12.0 0.1 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box PHD PF00628.29 KZN85780.1 - 1.7e-08 34.2 9.7 1.7e-08 34.2 9.7 1.9 2 0 0 2 2 2 1 PHD-finger DUF1524 PF07510.11 KZN85780.1 - 0.0036 17.2 2.9 0.016 15.0 0.4 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1524) PHD_2 PF13831.6 KZN85780.1 - 0.0047 16.4 5.9 0.0047 16.4 5.9 1.9 2 0 0 2 2 2 1 PHD-finger C1_2 PF03107.16 KZN85780.1 - 5.1 7.5 6.6 0.91 9.9 1.9 2.1 2 0 0 2 2 2 0 C1 domain Rcd1 PF04078.13 KZN85781.1 - 3.9e-126 419.7 2.3 4.6e-126 419.4 2.3 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like TFIIA PF03153.13 KZN85781.1 - 2.8 7.9 15.0 3.4 7.6 15.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ARS2 PF04959.13 KZN85781.1 - 8.5 6.7 10.0 13 6.1 10.0 1.2 1 0 0 1 1 1 0 Arsenite-resistance protein 2 Insulin_TMD PF17870.1 KZN85782.1 - 0.36 10.9 1.4 0.9 9.7 1.4 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF4690 PF15756.5 KZN85782.1 - 7.8 7.2 10.1 0.18 12.4 2.3 2.4 4 0 0 4 4 4 0 Small Novel Rich in Cartilage Gram_pos_anchor PF00746.21 KZN85782.1 - 8.2 6.5 13.5 2.7 8.0 0.2 3.4 3 0 0 3 3 3 0 LPXTG cell wall anchor motif POR_N PF01855.19 KZN85783.1 - 0.33 10.6 4.8 0.65 9.7 4.8 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg HAD_2 PF13419.6 KZN85785.1 - 9.2e-09 35.6 0.0 1.9e-08 34.6 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KZN85785.1 - 0.0018 18.3 0.0 0.0049 16.9 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KZN85785.1 - 0.015 15.6 0.0 0.028 14.7 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DIOX_N PF14226.6 KZN85786.1 - 6.2e-30 104.4 0.0 9.4e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KZN85786.1 - 1.8e-15 57.2 0.0 3e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sld5 PF05916.11 KZN85787.1 - 1.2e-12 48.2 0.0 1.9e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein FliT PF05400.13 KZN85787.1 - 0.015 16.1 0.1 0.22 12.4 0.0 2.7 3 0 0 3 3 3 0 Flagellar protein FliT Sulfate_transp PF00916.20 KZN85788.1 - 7.7e-63 212.5 25.5 1.1e-62 212.0 25.5 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 KZN85788.1 - 2e-15 56.6 0.0 3.6e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 KZN85788.1 - 3.5e-12 46.0 0.1 6.5e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 STAS domain RTT107_BRCT_5 PF16770.5 KZN85790.1 - 8.4e-35 118.7 0.0 4.9e-31 106.6 0.0 4.2 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 KZN85790.1 - 4.3e-33 113.1 3.5 3.9e-20 71.6 0.4 6.0 6 1 0 6 6 6 4 twin BRCT domain BRCT PF00533.26 KZN85790.1 - 9.2e-29 99.7 0.0 7.3e-09 35.9 0.0 6.7 6 2 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KZN85790.1 - 2.6e-25 88.6 0.0 3.5e-05 24.1 0.0 6.3 6 0 0 6 6 6 5 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KZN85790.1 - 8.7e-10 38.8 0.0 0.0028 17.9 0.0 4.2 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 KZN85790.1 - 0.00031 20.7 0.0 1.4 9.0 0.0 4.2 5 0 0 5 5 5 1 BRCA1 C Terminus (BRCT) domain Nucleo_P87 PF07267.11 KZN85790.1 - 0.3 9.9 7.4 0.49 9.2 7.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SOG2 PF10428.9 KZN85790.1 - 0.31 10.2 4.6 0.47 9.6 4.6 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein ESCRT-II PF05871.12 KZN85791.1 - 8.6e-52 175.1 0.0 1.1e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Methyltransf_4 PF02390.17 KZN85792.1 - 1.5e-45 154.8 0.4 2.3e-32 111.8 0.3 3.0 2 1 0 2 2 2 2 Putative methyltransferase Methyltransf_25 PF13649.6 KZN85792.1 - 0.00082 20.0 0.0 0.0057 17.3 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN85792.1 - 0.0011 19.7 0.0 0.0035 18.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KZN85792.1 - 0.0031 17.1 0.0 0.071 12.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KZN85792.1 - 0.011 15.7 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KZN85792.1 - 0.026 14.3 0.0 0.052 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KZN85792.1 - 0.041 14.5 0.0 2.9 8.6 0.0 3.1 3 0 0 3 3 3 0 Methyltransferase domain DUF913 PF06025.12 KZN85792.1 - 0.11 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FmrO PF07091.11 KZN85792.1 - 0.17 11.4 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) LIM PF00412.22 KZN85793.1 - 4.2e-26 90.9 25.6 2.6e-10 40.4 3.6 3.7 3 1 0 3 3 3 3 LIM domain Zn_ribbon_recom PF13408.6 KZN85793.1 - 0.079 13.5 1.3 0.23 12.0 0.1 2.4 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain MFS_1 PF07690.16 KZN85794.1 - 1.7e-23 83.1 45.1 5.6e-23 81.4 45.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KZN85794.1 - 2.1e-05 23.3 10.3 2.1e-05 23.3 10.3 2.2 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.7 KZN85794.1 - 0.095 11.5 25.9 0.33 9.8 0.1 2.9 2 1 1 3 3 3 0 MFS_1 like family RNB PF00773.19 KZN85795.1 - 5.6e-100 334.8 0.1 1.2e-99 333.8 0.0 1.5 2 0 0 2 2 2 1 RNB domain Rrp44_S1 PF17215.3 KZN85795.1 - 1.2e-29 102.1 0.8 1.2e-29 102.1 0.8 1.9 2 0 0 2 2 2 1 S1 domain Rrp44_CSD1 PF17216.3 KZN85795.1 - 1.4e-29 102.8 0.0 4.2e-29 101.2 0.0 1.9 1 1 0 1 1 1 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 KZN85795.1 - 2.7e-20 72.2 0.0 6.8e-20 70.9 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 KZN85795.1 - 3.5e-08 33.8 0.1 2.3e-07 31.2 0.0 2.3 2 0 0 2 2 2 1 PIN domain CSD2 PF17876.1 KZN85795.1 - 6.7e-08 32.6 0.1 2.7e-05 24.2 0.0 3.0 3 0 0 3 3 3 2 Cold shock domain CN_hydrolase PF00795.22 KZN85796.1 - 3.3e-55 187.2 0.0 3.7e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ESSS PF10183.9 KZN85797.1 - 3.1e-18 65.9 0.0 3.6e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Dna2 PF08696.11 KZN85798.1 - 8.4e-67 224.9 0.1 1.4e-66 224.2 0.1 1.4 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 KZN85798.1 - 3.2e-51 173.8 0.0 4.8e-51 173.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KZN85798.1 - 1.9e-32 113.1 0.4 7e-16 58.8 0.0 2.9 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 KZN85798.1 - 3.9e-15 56.1 0.0 7.8e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KZN85798.1 - 3.5e-12 46.9 0.1 7.9e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.7 KZN85798.1 - 7.2e-08 32.7 0.9 1.2e-07 31.9 0.2 1.7 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.18 KZN85798.1 - 4.1e-05 23.4 0.7 0.46 10.2 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KZN85798.1 - 0.00017 21.2 0.1 0.00033 20.3 0.1 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 KZN85798.1 - 0.00021 21.2 0.0 0.00044 20.1 0.0 1.5 1 0 0 1 1 1 1 Helicase SRP54 PF00448.22 KZN85798.1 - 0.0016 18.1 0.6 0.0029 17.3 0.1 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 KZN85798.1 - 0.0027 18.1 0.0 0.0072 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Csa1 PF06023.12 KZN85798.1 - 0.0029 17.0 0.1 0.0084 15.5 0.1 1.6 1 1 0 1 1 1 1 CRISPR-associated exonuclease Csa1 PIF1 PF05970.14 KZN85798.1 - 0.006 15.8 0.2 0.031 13.4 0.2 2.0 1 1 0 1 1 1 1 PIF1-like helicase CbiA PF01656.23 KZN85798.1 - 0.01 15.9 0.1 0.028 14.5 0.1 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.7 KZN85798.1 - 0.039 13.5 0.1 0.087 12.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KZN85798.1 - 0.04 14.1 0.6 1 9.5 0.1 2.6 1 1 1 2 2 2 0 AAA domain DUF2075 PF09848.9 KZN85798.1 - 0.041 13.1 0.1 0.2 10.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KZN85798.1 - 0.052 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 KZN85798.1 - 0.054 13.1 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 KZN85798.1 - 0.065 13.3 0.2 0.18 11.9 0.2 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain MeaB PF03308.16 KZN85798.1 - 0.076 12.0 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 KZN85798.1 - 0.083 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 KZN85798.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KZN85798.1 - 0.15 12.7 0.0 0.54 10.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KZN85798.1 - 0.16 12.4 0.0 0.41 11.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KZN85798.1 - 0.22 11.8 0.5 1.6 9.0 0.1 2.6 2 1 0 2 2 2 0 AAA domain ADP_ribosyl_GH PF03747.14 KZN85799.1 - 0.029 14.1 0.1 0.051 13.3 0.1 1.5 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase Ribonuc_P_40 PF08584.11 KZN85800.1 - 4.8e-64 216.4 0.0 3.8e-61 206.9 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease P 40kDa (Rpp40) subunit WD40 PF00400.32 KZN85801.1 - 1.7e-23 82.4 10.3 9.4e-07 29.4 0.0 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN85801.1 - 6e-16 58.5 0.0 0.0072 16.6 0.0 6.2 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KZN85801.1 - 2.9e-08 32.7 0.0 3.4e-05 22.5 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.11 KZN85801.1 - 0.00024 21.1 0.0 0.45 10.4 0.0 3.2 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 KZN85801.1 - 0.024 13.6 0.3 0.043 12.7 0.0 1.5 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 KZN85801.1 - 0.025 13.2 0.2 0.4 9.3 0.1 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 VID27 PF08553.10 KZN85801.1 - 0.16 11.0 0.1 0.9 8.5 0.0 1.9 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain PD40 PF07676.12 KZN85801.1 - 0.35 10.9 5.8 17 5.5 0.1 4.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Fungal_trans PF04082.18 KZN85802.1 - 1.3e-18 67.0 0.0 2.5e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN85802.1 - 1.5e-09 37.8 9.8 2.8e-09 36.9 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L2_C PF03947.18 KZN85803.1 - 5.2e-50 168.9 0.6 5.2e-50 168.9 0.6 2.6 2 2 1 3 3 3 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KZN85803.1 - 3.8e-24 84.4 0.2 7.4e-24 83.5 0.2 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.23 KZN85804.1 - 1.1e-45 154.4 0.1 7.8e-45 151.7 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KZN85804.1 - 8.4e-36 122.7 0.1 1.4e-35 121.9 0.1 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain APH PF01636.23 KZN85805.1 - 2e-15 57.4 0.0 2.5e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN85805.1 - 0.0006 19.5 0.0 0.00093 18.8 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase DUF1462 PF07315.11 KZN85805.1 - 0.064 13.5 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) HIT PF01230.23 KZN85806.1 - 1e-16 61.4 0.3 3.3e-16 59.8 0.2 1.7 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 KZN85806.1 - 0.00012 22.5 0.0 0.00021 21.8 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KZN85806.1 - 0.0035 17.2 0.0 0.015 15.2 0.0 1.9 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 UPF0020 PF01170.18 KZN85807.1 - 2.7e-07 30.5 0.1 0.00011 22.0 0.1 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 KZN85807.1 - 0.085 12.6 0.0 0.47 10.1 0.0 2.0 2 0 0 2 2 2 0 DNA methylase N6_Mtase PF02384.16 KZN85807.1 - 0.19 11.0 0.0 0.44 9.8 0.0 1.6 1 1 0 1 1 1 0 N-6 DNA Methylase SIR2 PF02146.17 KZN85808.1 - 1.5e-59 200.8 0.0 2.2e-59 200.4 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KZN85808.1 - 0.00063 19.5 0.0 0.13 12.0 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 KZN85808.1 - 0.00097 18.9 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPR_2 PF07719.17 KZN85809.1 - 5.3e-09 35.5 0.8 0.01 15.9 0.0 5.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KZN85809.1 - 5.9e-09 35.4 0.0 0.0018 18.3 0.0 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KZN85809.1 - 7.5e-08 32.6 8.1 2.6e-07 30.8 0.3 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KZN85809.1 - 3.6e-07 30.7 5.8 0.0033 18.0 0.7 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KZN85809.1 - 7.2e-07 28.9 7.0 2.2e-06 27.3 0.2 2.5 2 1 0 2 2 2 1 MalT-like TPR region TPR_11 PF13414.6 KZN85809.1 - 2e-06 27.3 0.3 0.041 13.6 0.0 3.3 4 0 0 4 4 4 2 TPR repeat TPR_19 PF14559.6 KZN85809.1 - 2.3e-06 28.0 12.4 0.0031 18.0 2.8 4.0 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 KZN85809.1 - 2.7e-05 24.6 13.0 0.0098 16.6 1.1 5.6 5 2 2 7 7 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KZN85809.1 - 0.00014 21.5 0.3 0.064 13.1 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KZN85809.1 - 0.0039 17.1 3.7 2.9 8.1 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KZN85809.1 - 0.0049 17.2 0.1 1.6e+02 3.0 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KZN85809.1 - 0.0051 17.0 0.1 6.2 7.1 0.0 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 KZN85809.1 - 0.012 16.2 0.4 0.012 16.2 0.4 4.0 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 KZN85809.1 - 0.03 14.5 9.5 1.7 8.9 0.8 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KZN85809.1 - 0.035 14.0 3.1 0.99 9.4 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 KZN85809.1 - 0.2 11.4 2.5 0.41 10.3 0.1 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 KZN85809.1 - 0.35 11.6 9.6 49 4.9 0.5 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat RWD PF05773.22 KZN85810.1 - 2.9e-23 82.3 0.4 2.9e-23 82.3 0.4 1.6 2 0 0 2 2 2 1 RWD domain DFRP_C PF16543.5 KZN85810.1 - 0.0086 16.5 17.7 0.04 14.4 17.0 2.4 1 1 1 2 2 2 1 DRG Family Regulatory Proteins, Tma46 AP3D1 PF06375.11 KZN85810.1 - 0.037 14.3 6.9 0.06 13.6 6.9 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 PIEZO PF15917.5 KZN85810.1 - 0.1 12.1 5.4 0.13 11.7 5.4 1.1 1 0 0 1 1 1 0 Piezo Vfa1 PF08432.10 KZN85810.1 - 0.27 11.6 8.5 0.39 11.0 8.5 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 HA2 PF04408.23 KZN85810.1 - 5.7 7.3 8.8 2.6e+02 1.9 8.8 2.2 1 1 0 1 1 1 0 Helicase associated domain (HA2) Complex1_LYR PF05347.15 KZN85811.1 - 1.5e-12 47.4 0.1 6.4e-12 45.3 0.0 2.1 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KZN85811.1 - 0.011 16.4 0.1 0.024 15.3 0.1 1.7 1 1 0 1 1 1 0 Complex1_LYR-like UQ_con PF00179.26 KZN85812.1 - 3e-17 62.6 0.0 3.6e-17 62.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KZN85812.1 - 0.049 13.9 0.0 0.05 13.9 0.0 1.2 1 0 0 1 1 1 0 RWD domain Sec7_N PF12783.7 KZN85813.1 - 4.9e-43 146.8 5.8 2.2e-40 138.2 0.0 4.3 4 1 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KZN85813.1 - 9.8e-42 142.6 3.4 2.6e-41 141.2 3.4 1.8 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 KZN85813.1 - 4.5e-22 78.0 3.4 9.4e-22 77.0 2.1 1.9 2 0 0 2 2 2 1 C-terminal region of Mon2 protein DUF1981 PF09324.10 KZN85813.1 - 0.008 16.0 0.1 0.91 9.4 0.0 4.5 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) YhdB PF14148.6 KZN85813.1 - 0.47 10.6 3.6 4.2 7.5 0.7 2.5 2 0 0 2 2 2 0 YhdB-like protein Vps26 PF03643.15 KZN85814.1 - 5.3e-129 429.1 0.2 6.5e-129 428.8 0.2 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KZN85814.1 - 0.00022 21.3 0.1 0.6 10.2 0.0 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KZN85814.1 - 0.0072 16.8 0.1 0.1 13.0 0.0 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain SKI PF01202.22 KZN85815.1 - 2.5e-11 44.0 0.0 5.9e-11 42.7 0.0 1.6 1 1 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 KZN85815.1 - 4.1e-08 33.8 0.0 2.3e-07 31.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KZN85815.1 - 8.8e-08 32.4 0.0 1.4e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain dNK PF01712.19 KZN85815.1 - 8.2e-06 25.8 0.1 0.034 14.0 0.2 2.1 2 0 0 2 2 2 2 Deoxynucleoside kinase Rad17 PF03215.15 KZN85815.1 - 0.00079 19.4 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_17 PF13207.6 KZN85815.1 - 0.0011 19.4 0.1 0.024 15.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KZN85815.1 - 0.006 16.3 0.0 0.018 14.7 0.0 1.7 2 0 0 2 2 2 1 Cytidylate kinase AAA_22 PF13401.6 KZN85815.1 - 0.018 15.3 0.2 0.047 14.0 0.2 1.9 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.22 KZN85815.1 - 0.026 14.9 0.0 0.072 13.5 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 KZN85815.1 - 0.026 14.9 0.0 0.04 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KZN85815.1 - 0.056 14.0 0.2 0.091 13.3 0.2 1.7 1 1 0 1 1 1 0 ABC transporter Thymidylate_kin PF02223.17 KZN85815.1 - 0.072 12.8 0.1 0.71 9.5 0.1 2.1 2 0 0 2 2 2 0 Thymidylate kinase CoaE PF01121.20 KZN85815.1 - 0.082 12.6 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase RsgA_GTPase PF03193.16 KZN85815.1 - 0.083 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase T2SSE PF00437.20 KZN85815.1 - 0.084 11.9 0.1 0.15 11.1 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 KZN85815.1 - 0.097 13.1 0.0 0.25 11.8 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KZN85815.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain 2-oxoacid_dh PF00198.23 KZN85816.1 - 9.4e-79 264.1 0.2 1.4e-78 263.6 0.2 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KZN85816.1 - 8.4e-14 51.2 0.0 2.1e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KZN85816.1 - 1.8e-11 44.2 1.1 4.5e-11 42.9 0.1 2.2 2 0 0 2 2 2 1 e3 binding domain COesterase PF00135.28 KZN85817.1 - 3.8e-79 266.9 4.4 1.1e-78 265.3 4.4 1.6 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KZN85817.1 - 7.4e-05 22.3 0.2 0.00017 21.1 0.2 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KZN85817.1 - 0.0014 18.5 0.0 0.0033 17.3 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold YugN PF08868.10 KZN85817.1 - 0.15 12.0 0.7 1.1 9.1 0.1 2.2 2 0 0 2 2 2 0 YugN-like family PI-PLC-X PF00388.19 KZN85818.1 - 4.5e-09 36.0 0.0 2.2e-08 33.8 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain Ribosomal_L10 PF00466.20 KZN85819.1 - 0.033 14.3 0.0 0.27 11.4 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L10 Glycos_transf_3 PF00591.21 KZN85820.1 - 3.4e-58 197.2 0.0 6.9e-56 189.7 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KZN85820.1 - 4.8e-09 35.9 0.3 1.2e-08 34.7 0.3 1.7 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain DNA_RNApol_7kD PF03604.13 KZN85821.1 - 4.4e-17 61.5 5.7 5.6e-17 61.1 5.7 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.19 KZN85821.1 - 0.00093 19.2 0.1 0.001 19.1 0.1 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2197 PF09963.9 KZN85821.1 - 0.0014 18.8 0.8 0.14 12.4 0.0 2.2 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2197) zf_UBZ PF18439.1 KZN85821.1 - 0.0014 18.1 0.8 1.1 8.9 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger DZR PF12773.7 KZN85821.1 - 0.013 15.5 0.3 0.018 15.0 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon zinc-ribbon_6 PF10005.9 KZN85821.1 - 0.03 15.0 0.2 0.041 14.6 0.2 1.2 1 0 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KZN85821.1 - 0.45 10.7 3.4 3 8.0 3.4 2.0 1 1 2 3 3 3 0 Zinc ribbon domain Fe_hyd_lg_C PF02906.14 KZN85822.1 - 3.2e-49 167.8 0.0 6.4e-49 166.8 0.0 1.5 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain DUF2263 PF10021.9 KZN85823.1 - 1.7e-21 77.2 0.0 1.2e-20 74.4 0.0 2.2 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 KZN85823.1 - 0.0053 16.8 0.0 0.15 12.1 0.0 2.3 2 0 0 2 2 2 1 Macro domain Herpes_IE68 PF02479.16 KZN85823.1 - 0.074 12.7 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus immediate early protein NRDE-2 PF08424.10 KZN85823.1 - 0.098 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Fapy_DNA_glyco PF01149.24 KZN85825.1 - 1.9e-35 122.0 0.0 3.3e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 KZN85825.1 - 1.2e-21 76.5 0.0 2.1e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 KZN85825.1 - 0.0034 16.2 0.0 0.0073 15.1 0.0 1.5 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DTHCT PF08070.11 KZN85825.1 - 0.68 10.7 8.0 1.6 9.5 8.0 1.6 1 0 0 1 1 1 0 DTHCT (NUC029) region Cid2 PF09774.9 KZN85826.1 - 1e-55 188.5 0.9 1.2e-55 188.3 0.9 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 NARP1 PF12569.8 KZN85827.1 - 2.4e-219 729.5 17.1 8.2e-217 721.2 11.5 2.2 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 KZN85827.1 - 1.9e-16 58.8 24.5 0.00043 20.2 0.2 10.3 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 KZN85827.1 - 2.8e-16 59.7 19.3 0.0065 17.0 0.9 7.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 KZN85827.1 - 6.1e-15 54.6 18.2 0.026 15.3 0.2 11.1 7 3 4 11 11 11 3 Tetratricopeptide repeat TPR_16 PF13432.6 KZN85827.1 - 1.7e-13 51.0 12.6 0.0045 17.6 0.7 7.5 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 KZN85827.1 - 6.9e-10 38.3 19.9 0.00011 21.8 0.2 8.3 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 KZN85827.1 - 2e-07 30.7 20.8 0.001 19.1 0.1 8.1 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 KZN85827.1 - 5.3e-07 29.2 11.6 0.00024 20.7 0.1 5.3 6 0 0 6 6 6 2 TPR repeat TPR_9 PF13371.6 KZN85827.1 - 9.7e-07 28.9 7.1 0.005 17.0 2.1 4.4 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KZN85827.1 - 1.4e-06 28.4 17.3 0.31 11.4 0.3 6.9 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KZN85827.1 - 5.2e-06 26.5 10.1 3.9 8.1 0.1 6.7 6 0 0 6 6 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KZN85827.1 - 2.3e-05 24.5 17.5 0.0078 16.4 0.7 5.8 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KZN85827.1 - 0.0019 17.5 1.3 0.0019 17.5 1.3 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF3087 PF11286.8 KZN85827.1 - 0.0059 16.1 2.2 0.17 11.4 0.3 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3087) Fis1_TPR_C PF14853.6 KZN85827.1 - 0.03 14.4 6.9 11 6.2 0.0 5.0 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 KZN85827.1 - 0.061 13.3 0.1 0.58 10.2 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4543 PF15076.6 KZN85827.1 - 0.16 12.1 0.6 2.2 8.5 0.0 3.4 4 0 0 4 4 2 0 Domain of unknown function (DUF4543) TPR_6 PF13174.6 KZN85827.1 - 0.18 12.5 18.7 9.6 7.1 0.2 7.0 8 0 0 8 8 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KZN85827.1 - 0.78 10.5 13.8 0.17 12.6 0.7 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat BTAD PF03704.17 KZN85827.1 - 0.89 10.0 7.3 0.26 11.7 1.2 3.0 1 1 1 2 2 2 0 Bacterial transcriptional activator domain MIT PF04212.18 KZN85827.1 - 6.3 7.0 13.3 3 8.0 0.2 5.3 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 KZN85827.1 - 7.4 6.9 10.5 46 4.4 0.1 5.8 5 1 1 6 6 5 0 Tetratricopeptide repeat Tim54 PF11711.8 KZN85828.1 - 1.2e-151 504.8 0.1 1.4e-151 504.6 0.1 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Tyrosinase PF00264.20 KZN85829.1 - 5.1e-25 89.1 1.8 7.8e-25 88.5 1.8 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF2573 PF10835.8 KZN85829.1 - 0.012 16.0 0.0 0.15 12.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2573) HD PF01966.22 KZN85830.1 - 0.00023 21.4 0.1 0.00062 20.0 0.0 1.7 1 1 1 2 2 2 1 HD domain Glyco_hydro_20 PF00728.22 KZN85831.1 - 1.9e-32 113.0 0.0 1.4e-21 77.3 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain GGACT PF06094.12 KZN85831.1 - 1.1e-06 29.2 0.0 1.8e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Pkinase PF00069.25 KZN85832.1 - 1.9e-55 188.1 0.0 2.7e-54 184.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN85832.1 - 7.8e-25 87.6 0.4 2.2e-19 69.7 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KZN85832.1 - 4.3e-06 25.9 0.0 6.5e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KZN85832.1 - 0.00032 20.1 0.0 0.00065 19.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KZN85832.1 - 0.0005 19.5 0.2 0.0012 18.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KZN85832.1 - 0.00059 19.8 3.3 0.012 15.6 0.1 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KZN85832.1 - 0.0078 15.3 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 NFACT-C PF11923.8 KZN85832.1 - 0.018 15.0 0.1 0.041 13.8 0.1 1.6 1 0 0 1 1 1 0 NFACT protein C-terminal domain Pkinase_fungal PF17667.1 KZN85832.1 - 0.069 11.9 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase TFIIA PF03153.13 KZN85832.1 - 0.35 10.8 10.9 0.58 10.1 10.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SF3A2 PF16835.5 KZN85833.1 - 6.6e-36 122.6 0.1 1e-35 122.0 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KZN85833.1 - 8.7e-06 26.0 0.5 2e-05 24.8 0.5 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.11 KZN85833.1 - 0.044 13.3 1.5 0.11 12.1 1.5 1.7 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like CAP_GLY PF01302.25 KZN85834.1 - 4.7e-19 68.2 0.5 7.9e-19 67.4 0.5 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 KZN85834.1 - 4.5e-14 52.3 9.8 0.002 18.5 0.2 5.2 3 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KZN85834.1 - 4.8e-09 35.8 12.1 0.02 14.6 0.3 5.1 2 2 1 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 KZN85834.1 - 3.7e-06 26.6 8.4 0.15 12.1 0.1 6.3 7 0 0 7 7 7 2 Leucine Rich repeat LRR_9 PF14580.6 KZN85834.1 - 1.9e-05 24.2 0.8 0.074 12.5 0.1 3.9 1 1 3 4 4 4 1 Leucine-rich repeat LRR_1 PF00560.33 KZN85834.1 - 0.0021 18.4 4.9 11 7.0 0.1 5.7 6 0 0 6 6 6 1 Leucine Rich Repeat Hamartin PF04388.12 KZN85834.1 - 0.09 11.4 1.3 0.12 11.0 1.3 1.1 1 0 0 1 1 1 0 Hamartin protein Zn_clus PF00172.18 KZN85836.1 - 7.6e-08 32.4 8.8 7.6e-08 32.4 8.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-U1 PF06220.12 KZN85837.1 - 1.2e-05 24.9 0.1 2.1e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 U1 zinc finger CCDC84 PF14968.6 KZN85837.1 - 0.0036 17.0 0.5 0.0092 15.6 0.2 1.4 1 1 0 1 1 1 1 Coiled coil protein 84 WxL PF13731.6 KZN85837.1 - 0.13 12.3 6.8 0.25 11.4 6.8 1.4 1 0 0 1 1 1 0 WxL domain surface cell wall-binding 2-Hacid_dh_C PF02826.19 KZN85838.1 - 1.5e-58 197.1 0.0 2.1e-58 196.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KZN85838.1 - 5.9e-15 55.1 0.0 8.4e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KZN85838.1 - 0.00014 22.0 0.3 0.00027 21.2 0.3 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KZN85838.1 - 0.012 15.2 0.1 0.025 14.1 0.1 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 KZN85838.1 - 0.062 13.9 0.0 0.12 13.0 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 KZN85838.1 - 0.11 12.3 0.2 0.52 10.2 0.0 2.1 3 0 0 3 3 3 0 Rossmann-like domain CwfJ_C_2 PF04676.14 KZN85839.1 - 2.4e-29 102.1 0.1 8.8e-29 100.3 0.1 2.1 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 KZN85839.1 - 5.8e-29 100.4 0.0 4.6e-28 97.5 0.0 2.1 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 ATP_bind_1 PF03029.17 KZN85840.1 - 1.8e-72 244.0 0.0 2.6e-72 243.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KZN85840.1 - 1.4e-05 24.7 0.0 0.0017 18.0 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 KZN85840.1 - 0.00023 20.2 0.0 0.12 11.3 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KZN85840.1 - 0.00034 20.7 0.0 0.0021 18.1 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 KZN85840.1 - 0.0015 18.3 0.0 0.0036 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain PRK PF00485.18 KZN85840.1 - 0.0024 17.6 0.0 0.019 14.7 0.0 2.2 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.22 KZN85840.1 - 0.0029 17.3 0.0 0.023 14.4 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_7 PF12775.7 KZN85840.1 - 0.0031 17.1 0.0 0.0054 16.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 KZN85840.1 - 0.0031 17.9 0.0 0.0092 16.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KZN85840.1 - 0.0037 17.6 0.0 0.013 15.7 0.0 2.1 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 KZN85840.1 - 0.0042 17.0 0.0 0.0097 15.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KZN85840.1 - 0.005 16.0 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain FeoB_N PF02421.18 KZN85840.1 - 0.0055 16.3 0.0 0.28 10.7 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B G-alpha PF00503.20 KZN85840.1 - 0.0079 15.4 0.0 0.2 10.8 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit AAA_33 PF13671.6 KZN85840.1 - 0.0084 16.3 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 KZN85840.1 - 0.0097 15.5 0.0 0.96 9.0 0.0 2.3 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Methyltransf_32 PF13679.6 KZN85840.1 - 0.011 15.7 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AAA_30 PF13604.6 KZN85840.1 - 0.015 15.1 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KZN85840.1 - 0.018 15.3 0.0 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase CLP1_P PF16575.5 KZN85840.1 - 0.02 14.7 0.0 0.19 11.5 0.0 2.2 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Arf PF00025.21 KZN85840.1 - 0.028 13.9 0.0 9.2 5.7 0.0 3.1 3 0 0 3 3 3 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KZN85840.1 - 0.039 13.9 0.0 11 5.9 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase DUF87 PF01935.17 KZN85840.1 - 0.073 13.2 0.1 0.22 11.6 0.0 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain KAP_NTPase PF07693.14 KZN85840.1 - 0.1 11.8 0.6 0.34 10.1 0.6 1.9 1 1 0 1 1 1 0 KAP family P-loop domain GST_N_3 PF13417.6 KZN85842.1 - 6.1e-21 74.6 0.0 1.2e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KZN85842.1 - 2.3e-18 66.2 0.0 4.7e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KZN85842.1 - 2.2e-08 34.3 0.0 4.6e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KZN85842.1 - 7.8e-08 32.2 0.0 2.1e-07 30.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KZN85842.1 - 8.7e-05 23.1 0.0 0.00019 22.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KZN85842.1 - 0.001 19.2 0.0 0.003 17.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KZN85842.1 - 0.0017 18.5 0.0 0.0053 16.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KZN85842.1 - 0.027 14.7 0.2 0.094 12.9 0.0 2.1 2 0 0 2 2 2 0 Glutaredoxin SUZ PF12752.7 KZN85843.1 - 1.2e-05 25.9 2.5 1.2e-05 25.9 2.5 4.5 2 1 1 3 3 3 1 SUZ domain eIF3_subunit PF08597.10 KZN85843.1 - 0.082 12.8 9.6 0.89 9.4 3.9 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Aldo_ket_red PF00248.21 KZN85846.1 - 2e-51 175.0 0.0 5.6e-51 173.5 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family Hydrolase_6 PF13344.6 KZN85847.1 - 2.2e-21 75.9 0.0 3.6e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KZN85847.1 - 8.3e-20 70.6 0.0 2e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KZN85847.1 - 0.0017 18.7 0.0 0.42 10.9 0.0 2.8 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Apt1 PF10351.9 KZN85847.1 - 0.0053 15.7 0.4 0.028 13.3 0.0 1.9 2 0 0 2 2 2 1 Golgi-body localisation protein domain PGP_phosphatase PF09419.10 KZN85847.1 - 0.015 14.9 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase 5-nucleotidase PF06189.12 KZN85847.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 5'-nucleotidase HAD_2 PF13419.6 KZN85847.1 - 0.14 12.2 0.0 0.91 9.6 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase LRR_4 PF12799.7 KZN85848.1 - 0.00069 20.0 5.9 1.8 9.1 0.0 5.2 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KZN85848.1 - 0.0038 17.1 0.0 0.0099 15.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 KZN85848.1 - 0.2 11.4 4.6 13 5.7 0.8 4.3 3 2 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.6 KZN85848.1 - 0.55 10.4 9.9 0.79 9.9 0.2 4.6 5 0 0 5 5 5 0 Leucine Rich repeat BSD PF03909.17 KZN85850.1 - 9.6e-28 96.0 7.5 2.5e-14 53.0 0.9 3.0 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 KZN85850.1 - 3.2e-24 85.1 0.0 7.4e-24 83.9 0.0 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain PIN_8 PF18476.1 KZN85850.1 - 0.25 11.2 3.8 0.11 12.4 0.6 2.0 2 0 0 2 2 2 0 PIN like domain CysG_dimeriser PF10414.9 KZN85850.1 - 1.6 8.5 6.9 4.4 7.1 0.4 4.1 3 1 1 4 4 4 0 Sirohaem synthase dimerisation region DUF883 PF05957.13 KZN85850.1 - 5.4 7.7 8.0 6.5 7.4 1.9 3.6 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) DUF1751 PF08551.10 KZN85851.1 - 0.034 14.7 0.1 0.063 13.8 0.1 1.5 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) CCD PF07860.11 KZN85851.1 - 0.043 13.9 0.1 0.084 12.9 0.1 1.4 1 0 0 1 1 1 0 WisP family C-Terminal Region ING PF12998.7 KZN85852.1 - 2.1e-12 47.5 0.0 5e-12 46.3 0.0 1.7 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KZN85852.1 - 1.6e-06 27.9 7.7 2.7e-06 27.2 7.7 1.4 1 0 0 1 1 1 1 PHD-finger DUF4378 PF14309.6 KZN85852.1 - 0.02 15.3 0.1 0.036 14.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) zf-HC5HC2H PF13771.6 KZN85852.1 - 0.073 13.3 1.0 0.16 12.2 1.0 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 KZN85852.1 - 0.31 10.6 2.8 0.58 9.8 2.8 1.4 1 0 0 1 1 1 0 PHD-finger Prp19 PF08606.11 KZN85852.1 - 3.3 7.8 6.3 8.2 6.5 2.0 2.4 2 0 0 2 2 2 0 Prp19/Pso4-like Transket_pyr PF02779.24 KZN85853.1 - 1.3e-65 220.4 0.0 2.3e-65 219.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KZN85853.1 - 7.4e-59 199.1 0.0 1.1e-58 198.5 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KZN85853.1 - 9.5e-56 187.7 0.0 1.6e-55 187.0 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KZN85853.1 - 2.8e-18 65.2 0.7 2.8e-18 65.2 0.7 1.9 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus Rhabdo_ncap PF00945.18 KZN85854.1 - 0.014 14.3 0.2 0.014 14.3 0.2 1.8 2 0 0 2 2 2 0 Rhabdovirus nucleocapsid protein APH PF01636.23 KZN85856.1 - 3.6e-08 33.6 0.0 6.4e-07 29.5 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family zf-AN1 PF01428.16 KZN85856.1 - 0.00053 20.1 10.5 0.00098 19.2 10.5 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Haspin_kinase PF12330.8 KZN85856.1 - 0.14 11.1 0.8 2.9 6.7 0.1 2.1 1 1 1 2 2 2 0 Haspin like kinase domain DJ-1_PfpI PF01965.24 KZN85857.1 - 8.6e-15 54.9 0.0 1.1e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 KZN85857.1 - 0.02 14.7 0.0 0.039 13.7 0.0 1.5 1 1 0 1 1 1 0 Glutamine amidotransferase class-I Sld5 PF05916.11 KZN85858.1 - 4.9e-20 72.0 0.0 6.2e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein Cnn_1N PF07989.11 KZN85859.1 - 6.1e-07 29.5 8.4 1.9e-06 27.9 8.4 1.9 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 MAD PF05557.13 KZN85859.1 - 0.0016 16.9 13.8 0.0023 16.4 13.8 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein IFT46_B_C PF12317.8 KZN85859.1 - 0.22 11.3 3.6 1.2 8.8 1.4 2.5 2 0 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal PKcGMP_CC PF16808.5 KZN85859.1 - 0.56 10.1 2.8 1.9 8.4 2.8 1.9 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase YabA PF06156.13 KZN85859.1 - 4.2 8.0 7.8 0.87 10.3 3.6 2.0 2 0 0 2 2 2 0 Initiation control protein YabA DUF2502 PF10697.9 KZN85860.1 - 0.013 15.8 1.0 0.025 14.9 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2502) F-box-like PF12937.7 KZN85861.1 - 0.065 13.1 0.9 2.4 8.1 0.0 2.8 2 0 0 2 2 2 0 F-box-like DUF3039 PF11238.8 KZN85861.1 - 0.09 12.5 0.1 5.7 6.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) Sod_Fe_C PF02777.18 KZN85862.1 - 3.4e-36 123.5 1.4 3.5e-36 123.5 0.2 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KZN85862.1 - 3.2e-29 101.2 2.0 5.4e-29 100.5 2.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain GCFC PF07842.12 KZN85863.1 - 1.5e-83 280.6 4.9 1.5e-83 280.6 4.9 1.5 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 KZN85863.1 - 1.2e-17 63.6 0.8 2.5e-17 62.5 0.8 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KZN85863.1 - 4.4e-08 33.1 0.7 4.4e-08 33.1 0.7 2.0 2 0 0 2 2 2 1 G-patch domain DHC_N1 PF08385.12 KZN85863.1 - 0.016 13.8 1.3 0.026 13.2 0.5 1.6 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 1 DUF5344 PF17279.2 KZN85863.1 - 0.018 15.6 0.6 0.036 14.6 0.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5344) IHABP4_N PF16174.5 KZN85863.1 - 0.59 10.7 11.8 1.4 9.5 11.8 1.6 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF4778 PF16008.5 KZN85863.1 - 0.82 9.7 6.4 1.4 9.0 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) VIT1 PF01988.19 KZN85864.1 - 4.4e-63 213.0 7.8 5.2e-63 212.8 7.8 1.1 1 0 0 1 1 1 1 VIT family DUF4202 PF13875.6 KZN85865.1 - 6.9e-80 267.3 1.1 7.8e-80 267.2 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) PilM_2 PF11104.8 KZN85865.1 - 0.036 13.1 0.0 0.046 12.7 0.0 1.1 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; PAM2 PF07145.15 KZN85865.1 - 0.14 11.9 0.1 0.26 11.1 0.1 1.4 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Sugar_tr PF00083.24 KZN85866.1 - 3e-81 273.6 21.5 3.7e-81 273.3 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN85866.1 - 2.1e-23 82.8 23.1 2.1e-23 82.8 23.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Caps_synth PF05704.12 KZN85866.1 - 0.1 11.9 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Gate PF07670.14 KZN85866.1 - 0.41 10.9 6.7 0.26 11.6 3.3 2.5 2 0 0 2 2 2 0 Nucleoside recognition Cation_efflux PF01545.21 KZN85867.1 - 2.1e-26 92.9 8.7 2.6e-26 92.6 8.7 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KZN85867.1 - 6.4e-11 42.2 0.2 1.1e-10 41.5 0.2 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF423 PF04241.15 KZN85867.1 - 0.23 11.7 5.4 7.7 6.8 0.2 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF423) DUF805 PF05656.14 KZN85867.1 - 9.6 6.7 7.8 47 4.5 7.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF805) p450 PF00067.22 KZN85868.1 - 9.2e-53 179.6 0.0 1.2e-52 179.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Rox3 PF08633.10 KZN85869.1 - 2.2e-66 224.1 0.4 2.2e-66 224.1 0.4 2.0 2 1 0 2 2 2 1 Rox3 mediator complex subunit Fungal_trans PF04082.18 KZN85870.1 - 6.1e-14 51.7 0.0 9.3e-14 51.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN85870.1 - 1.6e-09 37.7 11.4 2.7e-09 37.0 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ELMO_CED12 PF04727.13 KZN85870.1 - 0.027 14.6 0.0 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 ELMO/CED-12 family Fungal_trans PF04082.18 KZN85871.1 - 8.2e-19 67.7 0.1 1.2e-18 67.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN85871.1 - 4.6e-08 33.0 8.2 4.6e-08 33.0 8.2 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3094 PF11293.8 KZN85871.1 - 0.16 11.7 0.4 4 7.2 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) PhnA PF03831.14 KZN85872.1 - 0.79 9.6 3.8 0.48 10.3 1.5 1.8 2 0 0 2 2 2 0 PhnA domain MFS_1 PF07690.16 KZN85874.1 - 5.6e-39 134.1 27.6 8.9e-39 133.4 27.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN85874.1 - 4e-10 39.2 7.9 4e-10 39.2 7.9 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KZN85874.1 - 2.2e-07 29.7 3.0 2.2e-07 29.7 3.0 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) AtpR PF12966.7 KZN85874.1 - 0.99 9.9 7.3 0.14 12.6 1.9 2.4 2 0 0 2 2 2 0 N-ATPase, AtpR subunit CrgA PF06781.12 KZN85875.1 - 0.19 11.8 0.1 0.31 11.1 0.1 1.4 1 0 0 1 1 1 0 Cell division protein CrgA dCMP_cyt_deam_1 PF00383.23 KZN85877.1 - 3.5e-12 46.1 0.1 4.8e-12 45.6 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KZN85877.1 - 8.4e-10 38.5 0.0 1e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 KZN85877.1 - 0.00062 19.9 0.0 0.0014 18.7 0.1 1.5 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 KZN85877.1 - 0.032 14.3 2.1 0.11 12.6 0.4 2.1 1 1 1 2 2 2 0 Bd3614-like deaminase APOBEC3 PF18771.1 KZN85877.1 - 0.18 11.9 0.3 0.3 11.2 0.2 1.5 2 0 0 2 2 2 0 APOBEC3 DUF4449 PF14613.6 KZN85878.1 - 4.7e-60 202.4 0.1 4.7e-60 202.4 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) AIRC PF00731.20 KZN85879.1 - 1.8e-58 196.3 1.8 4.3e-58 195.1 1.8 1.6 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 KZN85879.1 - 2.4e-51 173.7 0.0 5.2e-51 172.6 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain PurK_C PF17769.1 KZN85879.1 - 3.8e-18 64.9 0.2 1e-17 63.5 0.2 1.8 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 KZN85879.1 - 1.1e-06 28.3 0.0 2.8e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 KZN85879.1 - 1.1e-05 25.0 0.0 7.8e-05 22.3 0.0 2.2 2 1 0 2 2 2 1 D-ala D-ala ligase C-terminus AlaDh_PNT_C PF01262.21 KZN85879.1 - 0.00084 18.7 0.0 0.0019 17.5 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ATP-grasp_5 PF13549.6 KZN85879.1 - 0.0035 16.8 0.0 0.0072 15.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Peptidase_M15_3 PF08291.11 KZN85879.1 - 0.0035 17.4 0.2 0.68 10.0 0.0 3.6 3 1 1 4 4 4 1 Peptidase M15 PrpR_N PF06506.11 KZN85879.1 - 0.0056 16.3 0.4 0.031 13.8 0.1 2.4 3 0 0 3 3 3 1 Propionate catabolism activator PPP4R2 PF09184.11 KZN85880.1 - 2.3e-08 34.0 1.3 2.3e-08 34.0 1.3 2.1 1 1 0 1 1 1 1 PPP4R2 HSF_DNA-bind PF00447.17 KZN85881.1 - 1.7e-31 108.7 1.9 3.8e-31 107.6 1.9 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 KZN85881.1 - 2.1e-22 79.4 0.0 5e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HMMR_C PF15908.5 KZN85881.1 - 0.03 14.6 0.4 0.063 13.6 0.4 1.5 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal FTO_CTD PF12934.7 KZN85881.1 - 0.054 13.3 0.6 0.14 12.0 0.2 1.8 2 0 0 2 2 2 0 FTO C-terminal domain DivIC PF04977.15 KZN85881.1 - 0.13 12.0 2.2 0.26 11.1 2.2 1.4 1 0 0 1 1 1 0 Septum formation initiator SlyX PF04102.12 KZN85881.1 - 0.14 12.8 9.7 0.071 13.7 6.6 2.2 2 0 0 2 2 2 0 SlyX Redoxin PF08534.10 KZN85882.1 - 1.1e-26 93.3 0.0 1.4e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KZN85882.1 - 2.4e-07 30.7 0.0 3.2e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family BolA PF01722.18 KZN85883.1 - 1.7e-19 69.9 0.0 8.1e-19 67.7 0.0 2.1 2 1 0 2 2 2 1 BolA-like protein NIF3 PF01784.18 KZN85884.1 - 2.6e-57 194.3 0.0 3.3e-57 193.9 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) ENTH PF01417.20 KZN85885.1 - 2e-47 160.3 0.1 4.3e-47 159.2 0.0 1.6 2 0 0 2 2 2 1 ENTH domain DUF1720 PF08226.11 KZN85885.1 - 0.00028 21.3 30.1 0.00028 21.3 30.1 5.8 1 1 3 4 4 4 1 Domain of unknown function (DUF1720) UIM PF02809.20 KZN85885.1 - 0.00085 19.1 6.8 0.0034 17.2 1.4 2.7 2 0 0 2 2 2 1 Ubiquitin interaction motif ANTH PF07651.16 KZN85885.1 - 0.0024 16.9 0.0 0.0039 16.2 0.0 1.3 1 0 0 1 1 1 1 ANTH domain DUF4264 PF14084.6 KZN85885.1 - 0.074 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) ADP_ribosyl_GH PF03747.14 KZN85886.1 - 9.3e-56 189.7 0.1 1.2e-55 189.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Chorismate_bind PF00425.18 KZN85887.1 - 6.8e-92 307.7 0.0 9.3e-92 307.2 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KZN85887.1 - 2.7e-29 102.2 0.0 4.8e-26 91.7 0.0 2.9 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region FragX_IP PF05994.11 KZN85887.1 - 0.26 9.3 0.0 0.37 8.8 0.0 1.1 1 0 0 1 1 1 0 Cytoplasmic Fragile-X interacting family ANAPC4_WD40 PF12894.7 KZN85888.1 - 4.6e-06 26.8 0.2 0.9 9.9 0.0 5.1 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KZN85888.1 - 2.1e-05 24.3 0.0 4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 KZN85888.1 - 0.0019 18.1 0.0 0.0054 16.6 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KZN85888.1 - 0.0086 16.0 1.3 6.1 6.9 0.0 4.1 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KZN85888.1 - 0.017 14.1 0.1 1.5 7.7 0.1 2.6 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 KZN85888.1 - 0.047 14.6 15.1 0.25 12.3 0.1 6.4 7 0 0 7 7 7 0 WD domain, G-beta repeat DUF1751 PF08551.10 KZN85889.1 - 6.1e-29 100.5 2.7 6.1e-29 100.5 2.7 1.7 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KZN85889.1 - 9e-05 22.5 6.5 0.00017 21.6 6.5 1.4 1 0 0 1 1 1 1 Rhomboid family DUF4149 PF13664.6 KZN85889.1 - 1.2 9.5 6.4 2.8 8.3 0.7 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) Ost5 PF05251.12 KZN85890.1 - 4.7e-17 62.0 10.2 5.4e-17 61.8 10.2 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 DUF2721 PF11026.8 KZN85890.1 - 1.4 8.8 6.0 1.6 8.6 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Bromodomain PF00439.25 KZN85891.1 - 1.1e-22 79.8 0.6 2.3e-22 78.9 0.6 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KZN85891.1 - 4.3e-08 33.4 0.0 7.6e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KZN85891.1 - 1.4e-06 28.2 0.1 3.2e-06 27.1 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KZN85891.1 - 0.00022 21.6 0.1 0.00039 20.8 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RGS PF00615.19 KZN85892.1 - 1.8e-11 44.3 0.0 2.4e-08 34.2 0.0 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain NMN_transporter PF04973.12 KZN85892.1 - 0.0092 16.0 4.4 0.016 15.2 4.4 1.4 1 0 0 1 1 1 1 Nicotinamide mononucleotide transporter PCI PF01399.27 KZN85893.1 - 0.0014 19.1 0.0 0.0025 18.3 0.0 1.4 1 0 0 1 1 1 1 PCI domain DUF1192 PF06698.11 KZN85893.1 - 0.25 11.4 3.9 0.49 10.5 3.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) DUF3584 PF12128.8 KZN85893.1 - 0.26 8.8 0.4 0.35 8.3 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HMA PF00403.26 KZN85894.1 - 3.6e-49 165.1 0.0 7.1e-12 45.6 0.0 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 KZN85894.1 - 3.7e-48 163.4 0.6 1.5e-47 161.5 0.6 2.1 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KZN85894.1 - 4.7e-36 125.1 0.3 9.2e-36 124.1 0.3 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KZN85894.1 - 3.7e-05 23.6 0.9 0.00023 21.0 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PASTA PF03793.19 KZN85894.1 - 0.1 12.5 0.1 0.44 10.4 0.1 2.1 1 0 0 1 1 1 0 PASTA domain EccE PF11203.8 KZN85894.1 - 1.9 8.8 6.8 3.7 7.9 0.3 4.1 5 0 0 5 5 5 0 Putative type VII ESX secretion system translocon, EccE W2 PF02020.18 KZN85895.1 - 4.7e-18 65.1 6.6 4.7e-18 65.1 6.6 2.8 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 KZN85895.1 - 1.8e-09 37.0 18.5 3.3e-06 26.6 1.4 4.6 2 1 3 5 5 5 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 KZN85895.1 - 2.4e-07 30.6 0.0 4.2e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KZN85895.1 - 0.00053 20.4 0.0 0.001 19.4 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KZN85895.1 - 0.0012 18.6 15.4 0.082 12.7 0.1 4.3 1 1 3 4 4 4 3 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KZN85895.1 - 0.0021 16.3 0.4 0.0056 14.9 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) DUF4483 PF14825.6 KZN85896.1 - 0.034 13.9 0.3 0.038 13.8 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) IBR PF01485.21 KZN85897.1 - 1.6e-21 76.2 46.0 4.1e-12 46.1 5.9 4.4 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KZN85897.1 - 3.2e-05 24.2 4.2 3.2e-05 24.2 4.2 3.7 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 KZN85897.1 - 0.00022 21.0 4.3 0.00022 21.0 4.3 4.4 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KZN85897.1 - 0.002 17.9 5.6 0.002 17.9 5.6 4.3 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KZN85897.1 - 0.0096 15.9 7.4 0.0096 15.9 7.4 4.0 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KZN85897.1 - 0.01 15.9 4.4 0.01 15.9 4.4 3.8 3 1 0 3 3 3 0 RING-type zinc-finger UN_NPL4 PF11543.8 KZN85897.1 - 0.011 16.2 0.0 0.022 15.3 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Mito_carr PF00153.27 KZN85898.1 - 1.7e-63 210.6 7.0 1.5e-22 79.3 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein AAA PF00004.29 KZN85899.1 - 3.7e-38 130.9 0.0 7.2e-38 130.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KZN85899.1 - 4.8e-08 32.9 0.0 2.2e-06 27.5 0.0 3.1 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 KZN85899.1 - 9.5e-07 28.5 0.5 2.8e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 AAA+ lid domain AAA_22 PF13401.6 KZN85899.1 - 1.1e-05 25.7 1.9 0.00024 21.4 0.1 3.2 2 1 2 4 4 4 1 AAA domain AAA_2 PF07724.14 KZN85899.1 - 5e-05 23.5 0.0 9.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KZN85899.1 - 7.4e-05 22.6 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KZN85899.1 - 0.00048 20.1 0.1 0.0027 17.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KZN85899.1 - 0.00083 18.6 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 KZN85899.1 - 0.0016 18.9 4.5 0.0018 18.7 1.1 2.9 2 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 KZN85899.1 - 0.0033 16.9 0.1 0.007 15.8 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KZN85899.1 - 0.0047 16.7 0.0 0.0085 15.8 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 KZN85899.1 - 0.0077 15.4 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 KZN85899.1 - 0.019 15.1 0.1 0.039 14.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KZN85899.1 - 0.027 14.5 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KZN85899.1 - 0.039 13.5 0.0 0.16 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KZN85899.1 - 0.05 13.3 0.0 0.099 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KZN85899.1 - 0.06 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 KZN85899.1 - 0.065 12.9 0.0 0.26 11.0 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 KZN85899.1 - 0.081 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 KZN85899.1 - 0.11 11.9 0.0 3.6 6.9 0.0 2.4 1 1 1 2 2 2 0 Bacterial TniB protein AAA_18 PF13238.6 KZN85899.1 - 0.11 13.1 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KZN85899.1 - 0.11 13.0 0.0 0.64 10.5 0.0 2.3 2 1 0 2 2 2 0 ABC transporter Guanylate_kin PF00625.21 KZN85899.1 - 0.17 11.6 0.0 0.41 10.3 0.0 1.6 1 0 0 1 1 1 0 Guanylate kinase PhoH PF02562.16 KZN85899.1 - 0.19 11.2 0.0 0.37 10.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein COG6 PF06419.11 KZN85900.1 - 9.2e-216 717.9 0.2 1e-215 717.7 0.2 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG2 PF06148.11 KZN85900.1 - 0.004 17.3 1.2 0.021 14.9 1.2 2.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Transcrip_act PF04949.13 KZN85900.1 - 0.018 14.9 0.9 0.061 13.2 0.9 1.9 1 0 0 1 1 1 0 Transcriptional activator GARP PF16731.5 KZN85900.1 - 0.042 13.5 2.3 0.063 13.0 1.2 1.9 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma Laminin_II PF06009.12 KZN85900.1 - 0.11 12.5 1.4 0.29 11.1 1.4 1.7 1 0 0 1 1 1 0 Laminin Domain II GTP-bdg_M PF16360.5 KZN85901.1 - 0.045 14.4 1.5 3.8 8.2 0.3 2.7 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region Pox_A_type_inc PF04508.12 KZN85901.1 - 0.53 10.2 3.2 45 4.1 0.0 3.6 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF4407 PF14362.6 KZN85901.1 - 2.2 7.5 10.4 0.11 11.8 1.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) SHE3 PF17078.5 KZN85901.1 - 2.7 7.6 7.1 0.42 10.3 0.1 2.6 2 1 0 3 3 3 0 SWI5-dependent HO expression protein 3 NYN PF01936.18 KZN85902.1 - 0.00073 20.0 0.0 0.0087 16.6 0.0 2.6 1 1 0 1 1 1 1 NYN domain HSP9_HSP12 PF04119.12 KZN85903.1 - 8.4e-25 86.9 8.9 8.4e-25 86.9 8.9 1.5 2 0 0 2 2 2 1 Heat shock protein 9/12 Mog1 PF04603.12 KZN85904.1 - 8.1e-28 97.5 0.0 2e-27 96.2 0.0 1.7 1 1 0 1 1 1 1 Ran-interacting Mog1 protein SET PF00856.28 KZN85905.1 - 8.6e-10 39.2 0.0 1.2e-09 38.7 0.0 1.5 1 1 0 1 1 1 1 SET domain adh_short PF00106.25 KZN85906.1 - 2.1e-37 128.5 0.0 2.7e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN85906.1 - 8.3e-22 77.9 0.0 1e-21 77.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN85906.1 - 1.1e-07 32.0 0.0 2e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KZN85906.1 - 7.3e-06 26.3 0.1 1.3e-05 25.5 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KZN85906.1 - 0.00068 19.7 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KZN85906.1 - 0.0011 19.6 0.1 0.0022 18.6 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 KZN85906.1 - 0.038 13.9 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.21 KZN85906.1 - 0.063 12.7 0.2 0.23 10.9 0.2 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KZN85906.1 - 0.074 12.2 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SprT-like PF10263.9 KZN85907.1 - 2.4e-26 91.8 0.2 4.2e-26 91.0 0.2 1.4 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 KZN85907.1 - 0.016 15.1 2.7 0.041 13.8 2.7 1.8 1 0 0 1 1 1 0 SprT-like zinc ribbon domain Pkinase PF00069.25 KZN85908.1 - 8.8e-11 41.7 0.1 1.2e-10 41.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN85908.1 - 2.3e-07 30.4 0.1 3.2e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KZN85908.1 - 3.8e-06 27.0 0.2 5.4e-06 26.5 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KZN85908.1 - 8.9e-06 25.2 0.2 1.4e-05 24.5 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KZN85908.1 - 0.0017 17.9 1.0 0.0031 17.1 0.9 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase WaaY PF06176.11 KZN85908.1 - 0.025 14.2 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_fungal PF17667.1 KZN85908.1 - 0.082 11.7 0.2 0.12 11.2 0.2 1.1 1 0 0 1 1 1 0 Fungal protein kinase EcKinase PF02958.20 KZN85908.1 - 0.13 11.5 0.1 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Glucan_synthase PF02364.15 KZN85909.1 - 0 1381.5 0.0 0 1380.5 0.0 1.5 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KZN85909.1 - 1.1e-43 148.6 0.5 3.1e-43 147.2 0.5 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Aminotran_1_2 PF00155.21 KZN85910.1 - 4.9e-40 137.8 0.0 5.7e-40 137.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KZN85910.1 - 0.0069 15.0 0.0 0.015 13.9 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Glyco_hydro_17 PF00332.18 KZN85911.1 - 2.5e-05 24.1 0.0 0.00027 20.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 FemAB PF02388.16 KZN85912.1 - 0.18 10.7 4.0 0.2 10.5 0.1 2.4 2 1 1 3 3 3 0 FemAB family WD40 PF00400.32 KZN85913.1 - 3.5e-08 34.0 0.2 2.8 9.0 0.1 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat RasGAP PF00616.19 KZN85914.1 - 4.6e-30 104.9 0.0 1.1e-20 74.3 0.0 2.8 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KZN85914.1 - 1.4e-06 28.5 0.0 1e-05 25.7 0.0 2.3 1 1 0 1 1 1 1 C2 domain APG9 PF04109.16 KZN85915.1 - 6.1e-210 698.2 11.5 7.2e-210 698.0 11.5 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 Glyco_hydro_47 PF01532.20 KZN85916.1 - 1.1e-186 621.3 0.0 1.3e-186 621.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF2013 PF09431.10 KZN85917.1 - 1.2e-51 174.5 3.7 1.4e-51 174.3 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) COQ9 PF08511.11 KZN85918.1 - 1.3e-22 79.3 0.1 2.2e-22 78.6 0.1 1.3 1 0 0 1 1 1 1 COQ9 RRM_1 PF00076.22 KZN85919.1 - 8.9e-50 166.4 0.0 2.9e-17 62.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KZN85919.1 - 2.2e-05 24.0 0.0 0.01 15.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KZN85919.1 - 0.00087 19.3 0.2 11 6.2 0.0 4.4 3 2 0 3 3 3 1 Limkain b1 PknH_C PF14032.6 KZN85919.1 - 0.0019 18.1 0.9 9.6 6.0 0.1 3.2 3 0 0 3 3 3 2 PknH-like extracellular domain RRM_3 PF08777.11 KZN85919.1 - 0.0062 16.6 0.0 15 5.7 0.0 3.5 3 1 0 3 3 3 2 RNA binding motif ATP-grasp_2 PF08442.10 KZN85919.1 - 0.14 11.7 0.0 0.65 9.5 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain PH PF00169.29 KZN85920.1 - 2.9e-06 27.7 0.1 3.9e-05 24.1 0.1 2.3 2 0 0 2 2 2 1 PH domain DUF3921 PF13060.6 KZN85920.1 - 0.03 14.3 0.0 0.079 13.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) Tim17 PF02466.19 KZN85921.1 - 1.7e-07 31.6 7.0 3.3e-07 30.6 6.4 1.8 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Na_H_antiport_3 PF07399.11 KZN85921.1 - 0.094 11.6 1.2 0.13 11.1 1.2 1.1 1 0 0 1 1 1 0 Putative Na+/H+ antiporter RPT PF13446.6 KZN85922.1 - 6.9e-47 157.2 0.2 6.3e-16 58.0 0.0 4.7 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH PF00443.29 KZN85922.1 - 5.4e-46 157.2 0.0 1.2e-45 156.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KZN85922.1 - 0.00026 20.7 0.1 0.0019 17.8 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase TolB_like PF15869.5 KZN85922.1 - 0.0072 15.6 0.4 0.15 11.2 0.0 2.3 2 0 0 2 2 2 1 TolB-like 6-blade propeller-like CoA_trans PF01144.23 KZN85923.1 - 1.1e-100 335.5 1.0 4.2e-60 202.8 0.3 2.0 2 0 0 2 2 2 2 Coenzyme A transferase DUF2981 PF11200.8 KZN85924.1 - 0.18 11.6 0.3 0.18 11.5 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DUF2370 PF10176.9 KZN85925.1 - 1.9e-92 309.0 0.2 9.2e-92 306.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) DUF2561 PF10812.8 KZN85925.1 - 0.073 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) DUF3632 PF12311.8 KZN85926.1 - 7e-25 88.5 8.6 9.3e-25 88.1 8.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) eIF3m_C_helix PF18005.1 KZN85926.1 - 0.084 12.6 0.3 0.084 12.6 0.3 1.9 2 0 0 2 2 2 0 eIF3 subunit M, C-terminal helix Cu-oxidase_3 PF07732.15 KZN85928.1 - 6.4e-09 35.9 0.0 5.6e-08 32.8 0.1 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KZN85928.1 - 5.5e-07 29.4 0.2 0.0005 19.8 0.2 3.2 2 1 0 2 2 2 1 Multicopper oxidase DUF4797 PF16051.5 KZN85928.1 - 0.074 13.0 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4797) Pkinase PF00069.25 KZN85930.1 - 7.3e-68 228.8 0.0 1.2e-67 228.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN85930.1 - 2.6e-31 108.8 0.0 4.1e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KZN85930.1 - 0.013 14.5 0.0 0.024 13.6 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KZN85930.1 - 0.046 13.1 0.0 0.092 12.1 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KZN85930.1 - 0.051 13.5 0.4 0.17 11.8 0.0 2.0 3 0 0 3 3 3 0 Phosphotransferase enzyme family Pkinase PF00069.25 KZN85931.1 - 9.8e-16 57.9 0.0 3.3e-08 33.2 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KZN85931.1 - 2.1e-08 33.8 0.0 0.0022 17.4 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KZN85931.1 - 0.0088 16.0 0.2 0.065 13.1 0.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KZN85931.1 - 0.021 14.2 0.1 2.7 7.2 0.0 2.8 3 0 0 3 3 3 0 Kinase-like DUF5051 PF16473.5 KZN85932.1 - 0.21 11.5 1.3 3.1 7.8 1.3 2.2 1 1 0 1 1 1 0 3' exoribonuclease, RNase T-like tRNA-synt_2b PF00587.25 KZN85933.1 - 4.6e-28 98.4 0.0 2e-26 93.1 0.0 2.3 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KZN85933.1 - 3.1e-16 59.3 0.2 6.9e-16 58.2 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 KZN85933.1 - 5e-14 52.1 0.0 9.3e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 KZN85933.1 - 3.2e-06 27.1 0.0 8.2e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 TGS domain Gar1 PF04410.14 KZN85934.1 - 3.2e-39 134.2 0.0 3.8e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region CDP-OH_P_transf PF01066.21 KZN85935.1 - 2.2e-10 41.1 1.0 6.6e-10 39.6 0.1 2.1 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Cation_efflux PF01545.21 KZN85935.1 - 0.014 15.2 1.6 1 9.1 0.1 2.1 2 0 0 2 2 2 0 Cation efflux family WSC PF01822.19 KZN85936.1 - 5.6e-12 45.7 9.6 5.6e-12 45.7 9.6 2.3 2 1 0 2 2 2 1 WSC domain SKG6 PF08693.10 KZN85936.1 - 5.1e-09 35.4 1.9 1.7e-08 33.7 1.9 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4366 PF14283.6 KZN85936.1 - 0.00064 19.8 1.2 0.0012 19.0 1.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Podoplanin PF05808.11 KZN85936.1 - 0.0076 16.4 5.8 0.012 15.8 5.8 1.2 1 0 0 1 1 1 1 Podoplanin DUF2165 PF09933.9 KZN85936.1 - 0.013 15.5 0.5 0.022 14.8 0.5 1.3 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) Sporozoite_P67 PF05642.11 KZN85936.1 - 0.014 13.5 7.9 0.017 13.2 7.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4448 PF14610.6 KZN85936.1 - 0.015 15.1 0.0 0.02 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) CbtA PF09490.10 KZN85936.1 - 0.27 11.0 4.5 0.051 13.4 1.0 1.5 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) DUF2681 PF10883.8 KZN85936.1 - 0.51 10.8 1.1 0.7 10.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DLIC PF05783.11 KZN85936.1 - 0.92 8.3 4.2 1.3 7.8 4.2 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) SprA-related PF12118.8 KZN85936.1 - 1.5 7.9 11.4 2.4 7.2 11.4 1.2 1 0 0 1 1 1 0 SprA-related family NiFe-hyd_HybE PF11939.8 KZN85937.1 - 0.035 14.0 0.0 0.042 13.7 0.0 1.1 1 0 0 1 1 1 0 [NiFe]-hydrogenase assembly, chaperone, HybE zf-C2H2 PF00096.26 KZN85938.1 - 2.8e-05 24.3 14.3 0.00061 20.1 1.7 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KZN85938.1 - 0.015 16.1 8.7 0.89 10.6 1.0 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KZN85938.1 - 6.3 7.4 15.4 1.5 9.3 3.8 3.5 3 0 0 3 3 3 0 Zinc-finger double domain G_glu_transpept PF01019.21 KZN85939.1 - 2.4e-139 465.4 0.0 3e-139 465.1 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase zf-piccolo PF05715.13 KZN85940.1 - 0.16 12.1 8.5 1.5 9.1 2.9 2.7 2 0 0 2 2 2 0 Piccolo Zn-finger FYVE_2 PF02318.16 KZN85940.1 - 0.91 9.8 8.1 0.84 9.9 2.2 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger MFS_1 PF07690.16 KZN85942.1 - 4.5e-49 167.3 49.8 1.2e-47 162.5 30.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN85942.1 - 4.7e-10 38.9 12.2 4.7e-10 38.9 12.2 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_4 PF06779.14 KZN85942.1 - 1.4e-05 24.6 11.1 3.6e-05 23.2 3.5 2.8 3 0 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KZN85942.1 - 0.71 8.1 15.8 0.62 8.3 0.4 3.3 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family TPMT PF05724.11 KZN85943.1 - 1.6e-25 90.1 0.0 4.2e-25 88.7 0.0 1.7 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 KZN85943.1 - 5e-05 23.9 0.0 8.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN85943.1 - 0.00032 21.4 0.0 0.00052 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN85943.1 - 0.0007 19.5 0.0 0.0009 19.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN85943.1 - 0.0013 18.5 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain N2227 PF07942.12 KZN85943.1 - 0.24 10.6 0.0 0.35 10.0 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein OTU PF02338.19 KZN85944.1 - 5.1e-20 72.2 0.3 7.8e-19 68.4 0.3 2.3 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KZN85944.1 - 1.9e-06 27.5 0.0 0.00016 21.2 0.0 2.5 2 0 0 2 2 2 1 Peptidase C65 Otubain Cep57_MT_bd PF06657.13 KZN85944.1 - 0.25 11.8 5.8 0.65 10.5 5.8 1.8 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 SICA_alpha PF12887.7 KZN85944.1 - 0.26 11.1 4.0 0.51 10.2 4.0 1.5 1 0 0 1 1 1 0 SICA extracellular alpha domain DUF3275 PF11679.8 KZN85944.1 - 0.95 9.4 6.2 1.7 8.6 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Ndc1_Nup PF09531.10 KZN85944.1 - 7.6 5.1 7.8 8.5 4.9 7.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup adh_short_C2 PF13561.6 KZN85945.1 - 2e-45 155.2 0.0 2.3e-45 155.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN85945.1 - 5.5e-43 146.7 0.0 7.4e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN85945.1 - 1.3e-06 28.5 0.0 2.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Trehalase PF01204.18 KZN85946.1 - 8.8e-192 638.5 0.0 1.1e-191 638.2 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 KZN85946.1 - 8.2e-17 60.6 1.1 1.4e-16 59.9 1.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain ICL PF00463.21 KZN85947.1 - 2.4e-300 996.5 3.0 2.8e-300 996.3 3.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KZN85947.1 - 7.5e-12 45.2 0.1 1.6e-11 44.1 0.1 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF3197 PF11432.8 KZN85947.1 - 0.026 14.4 0.3 5.4 6.9 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3197) NTF2 PF02136.20 KZN85948.1 - 1.7e-12 47.9 0.0 2.3e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 KZN85948.1 - 0.0012 19.2 0.0 0.0015 18.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 KZN85948.1 - 0.069 13.8 0.0 0.086 13.5 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain Choline_kinase PF01633.20 KZN85949.1 - 0.00081 19.0 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KZN85949.1 - 0.016 15.2 2.2 0.052 13.5 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family HSDR_N_2 PF13588.6 KZN85949.1 - 0.052 13.5 0.0 3.3 7.8 0.0 2.6 1 1 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Aldedh PF00171.22 KZN85950.1 - 2.6e-78 263.6 0.0 3.3e-78 263.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Adap_comp_sub PF00928.21 KZN85951.1 - 9.8e-62 208.7 0.0 3.9e-61 206.7 0.0 1.8 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KZN85951.1 - 0.00012 22.0 0.1 0.0002 21.3 0.1 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain YL1 PF05764.13 KZN85951.1 - 0.039 14.1 3.7 0.054 13.6 3.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Rubella_Capsid PF05750.11 KZN85951.1 - 0.058 13.0 8.1 0.1 12.2 8.1 1.3 1 0 0 1 1 1 0 Rubella capsid protein SWIRM-assoc_2 PF16496.5 KZN85951.1 - 0.71 8.7 6.3 1 8.2 6.3 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal DUF4536 PF15055.6 KZN85952.1 - 2.3e-06 27.8 4.8 1.2e-05 25.4 4.9 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4536) DUF4588 PF15251.6 KZN85953.1 - 2.1e-05 24.4 3.4 3.6e-05 23.7 0.2 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4588) SNF2_N PF00176.23 KZN85954.1 - 4e-78 262.6 0.1 6.6e-78 261.9 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KZN85954.1 - 5e-41 139.3 1.0 2e-40 137.4 1.0 2.1 1 0 0 1 1 1 1 SLIDE HAND PF09110.11 KZN85954.1 - 1.9e-38 131.6 2.3 1.9e-38 131.6 2.3 3.2 3 0 0 3 3 3 1 HAND Helicase_C PF00271.31 KZN85954.1 - 8.2e-18 64.8 0.0 9.8e-17 61.3 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KZN85954.1 - 5.8e-12 45.9 0.4 2.6e-11 43.8 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KZN85954.1 - 2.8e-05 24.0 0.0 7.6e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KZN85954.1 - 3.2e-05 23.7 0.1 0.00012 21.8 0.0 2.0 2 0 0 2 2 2 1 SWI2/SNF2 ATPase HDA2-3 PF11496.8 KZN85954.1 - 4e-05 22.9 0.0 0.00018 20.8 0.0 2.1 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD_2 PF06733.15 KZN85954.1 - 0.006 16.2 0.1 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 DEAD_2 AAA_14 PF13173.6 KZN85954.1 - 0.041 13.9 0.1 0.17 11.9 0.1 2.1 1 0 0 1 1 1 0 AAA domain DUF1086 PF06461.11 KZN85954.1 - 0.042 13.7 0.1 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1086) AAA_22 PF13401.6 KZN85954.1 - 0.097 12.9 0.1 0.48 10.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain Asp PF00026.23 KZN85955.1 - 1.4e-69 235.0 2.1 1.6e-69 234.7 2.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KZN85955.1 - 9.2e-15 55.3 0.8 4.7e-08 33.5 0.0 3.0 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KZN85955.1 - 0.0018 18.8 1.9 0.59 10.8 0.5 3.1 2 1 0 2 2 2 2 Aspartyl protease ADH_zinc_N PF00107.26 KZN85956.1 - 9.8e-22 77.3 0.7 1.9e-21 76.4 0.7 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KZN85956.1 - 4.9e-19 68.2 0.9 6.6e-19 67.8 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KZN85956.1 - 1.1e-06 28.3 2.7 1.6e-06 27.8 1.9 1.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KZN85956.1 - 0.00012 23.1 0.0 0.00026 22.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KZN85956.1 - 0.0021 17.4 0.4 0.0041 16.4 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 KZN85956.1 - 0.0059 16.2 0.1 0.01 15.4 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain UDPG_MGDP_dh_N PF03721.14 KZN85956.1 - 0.054 13.1 0.1 0.095 12.3 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KZN85956.1 - 0.084 12.2 0.4 0.17 11.2 0.1 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_18 PF12847.7 KZN85956.1 - 0.15 12.0 0.1 0.33 10.9 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase domain SpoU_methylase PF00588.19 KZN85957.1 - 8.1e-24 84.4 0.1 1.8e-22 80.1 0.1 2.4 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KZN85957.1 - 1.6e-06 28.3 0.0 3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding zf-PHD-like PF15446.6 KZN85958.1 - 2.6e-51 173.6 9.9 6.2e-51 172.4 9.9 1.7 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 KZN85958.1 - 2.7e-49 167.8 0.0 4.8e-49 166.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-CCCH_6 PF18585.1 KZN85958.1 - 2.1e-23 82.0 0.1 6.3e-23 80.4 0.1 1.9 1 0 0 1 1 1 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Helicase_C PF00271.31 KZN85958.1 - 2.9e-19 69.4 0.2 1.1e-18 67.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KZN85958.1 - 4.4e-13 49.1 2.6 1.5e-12 47.3 2.6 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.24 KZN85958.1 - 3.6e-06 26.8 0.8 0.14 12.1 0.1 3.2 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.29 KZN85958.1 - 1e-05 25.3 18.1 0.00079 19.3 5.7 3.7 3 1 1 4 4 4 2 PHD-finger ResIII PF04851.15 KZN85958.1 - 8.6e-05 22.6 0.0 0.00024 21.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-CCCH_7 PF18586.1 KZN85958.1 - 0.068 13.5 1.1 0.39 11.1 0.4 2.7 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 PHD_2 PF13831.6 KZN85958.1 - 0.42 10.2 12.7 0.36 10.4 6.5 3.3 2 1 1 3 3 3 0 PHD-finger Torus PF16131.5 KZN85960.1 - 0.011 16.4 0.2 0.026 15.2 0.2 1.6 1 0 0 1 1 1 0 Torus domain MRP-S28 PF10213.9 KZN85961.1 - 5e-45 153.0 0.1 8.4e-45 152.3 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DnaB_bind PF10410.9 KZN85961.1 - 0.06 13.5 0.1 0.48 10.6 0.1 2.3 1 1 1 2 2 2 0 DnaB-helicase binding domain of primase Glyco_tran_28_C PF04101.16 KZN85962.1 - 1.5e-20 73.8 0.1 3.3e-20 72.7 0.1 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Actin PF00022.19 KZN85963.1 - 4.8e-127 424.0 0.0 3e-126 421.3 0.0 1.8 1 1 0 1 1 1 1 Actin DUF3602 PF12223.8 KZN85964.1 - 2.4e-23 82.5 3.8 1.4e-20 73.6 0.3 2.4 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) zf-U1 PF06220.12 KZN85967.1 - 5e-16 58.2 2.1 7e-16 57.7 2.1 1.2 1 0 0 1 1 1 1 U1 zinc finger TRP PF06011.12 KZN85968.1 - 3.4e-167 556.5 19.3 4.7e-167 556.0 19.3 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KZN85968.1 - 6.1e-38 130.3 0.0 9.5e-38 129.7 0.0 1.3 1 0 0 1 1 1 1 ML-like domain Ac76 PF05814.11 KZN85968.1 - 0.11 12.5 5.2 6.5 6.8 0.1 3.3 2 1 0 3 3 3 0 Orf76 (Ac76) DEAD PF00270.29 KZN85969.1 - 5.4e-47 159.8 0.0 9.4e-47 159.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KZN85969.1 - 1.4e-23 83.3 0.0 8.3e-23 80.9 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KZN85969.1 - 1.4e-17 63.6 0.1 2.6e-17 62.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ERCC3_RAD25_C PF16203.5 KZN85969.1 - 0.00011 21.5 0.0 0.00021 20.6 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KZN85969.1 - 0.00012 22.1 0.0 0.00024 21.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit FYDLN_acid PF09538.10 KZN85969.1 - 2.2 9.0 10.0 4 8.2 10.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) GAGE PF05831.11 KZN85969.1 - 3.7 8.1 9.9 8.4 7.0 9.9 1.6 1 0 0 1 1 1 0 GAGE protein SWIRM-assoc_2 PF16496.5 KZN85969.1 - 5.1 5.9 9.4 8 5.2 9.4 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal T-box_assoc PF16176.5 KZN85969.1 - 5.5 7.0 6.9 9.1 6.3 6.9 1.2 1 0 0 1 1 1 0 T-box transcription factor-associated Flavin_Reduct PF01613.18 KZN85971.1 - 2.8e-17 63.2 0.0 3.8e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain UbiD PF01977.16 KZN85972.1 - 6.5e-120 400.7 0.0 1.1e-119 400.0 0.0 1.3 2 0 0 2 2 2 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase F-box PF00646.33 KZN85973.1 - 0.0019 18.0 0.3 0.0087 15.9 0.3 2.2 1 0 0 1 1 1 1 F-box domain Fungal_trans PF04082.18 KZN85975.1 - 9.9e-13 47.7 0.4 9.9e-13 47.7 0.4 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain Cep3 PF16846.5 KZN85975.1 - 0.0015 17.1 0.0 0.0022 16.5 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit B Y_phosphatase3 PF13350.6 KZN85975.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Peptidase_M24_C PF16188.5 KZN85975.1 - 0.17 11.9 0.7 55 3.9 0.1 3.2 3 0 0 3 3 3 0 C-terminal region of peptidase_M24 Flavoprotein PF02441.19 KZN85976.1 - 1.3e-24 86.7 0.0 1.6e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein Hydrolase PF00702.26 KZN85978.1 - 1.2e-16 61.6 0.0 1.9e-13 51.2 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KZN85978.1 - 6.3e-13 49.2 0.0 2.7e-12 47.1 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KZN85978.1 - 2.5e-05 24.2 0.0 5.8e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 KZN85978.1 - 0.007 16.8 0.2 0.089 13.2 0.2 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KZN85978.1 - 0.018 14.7 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase zf-CCHC PF00098.23 KZN85979.1 - 0.13 12.4 0.4 0.13 12.4 0.4 5.3 6 0 0 6 6 6 0 Zinc knuckle zf-CCCH_7 PF18586.1 KZN85979.1 - 1.5 9.2 5.3 26 5.2 2.8 2.7 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 UPF0560 PF10577.9 KZN85979.1 - 5.3 5.4 12.6 7.4 4.9 12.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 ORMDL PF04061.14 KZN85980.1 - 2.5e-58 195.7 3.1 2.9e-58 195.5 3.1 1.0 1 0 0 1 1 1 1 ORMDL family PI3K_C2 PF00792.24 KZN85980.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 PBP1_TM PF14812.6 KZN85981.1 - 2.6 8.5 8.5 0.44 11.0 3.1 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CH PF00307.31 KZN85982.1 - 2.8e-16 59.6 0.0 4.7e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF4677 PF15726.5 KZN85982.1 - 0.21 11.8 1.9 1 9.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4677) NDUFA12 PF05071.16 KZN85983.1 - 8.7e-12 45.7 12.4 6.8e-11 42.9 12.4 2.2 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Piwi PF02171.17 KZN85984.1 - 1.1e-66 225.1 0.0 1.7e-66 224.5 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 KZN85984.1 - 5.6e-15 54.8 0.3 1.5e-14 53.4 0.3 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 KZN85984.1 - 7.6e-13 49.3 0.0 1.5e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 KZN85984.1 - 1.3e-11 44.5 0.0 3.4e-11 43.1 0.0 1.7 1 1 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 KZN85984.1 - 4.3e-10 39.8 0.1 9.6e-10 38.6 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 KZN85984.1 - 9.4e-05 22.6 0.1 0.00019 21.6 0.1 1.5 1 0 0 1 1 1 1 Mid domain of argonaute Astro_capsid_p PF12226.8 KZN85986.1 - 0.2 10.8 5.4 0.38 9.9 5.4 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein EMP24_GP25L PF01105.24 KZN85988.1 - 2.1e-40 138.6 0.0 2.3e-40 138.5 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 KZN85988.1 - 0.12 10.6 0.4 0.15 10.2 0.4 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Sdh5 PF03937.16 KZN85989.1 - 1.6e-22 79.2 0.1 8.4e-22 76.9 0.1 2.0 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase WD40 PF00400.32 KZN85990.1 - 1.6e-44 149.0 24.0 3e-09 37.4 0.3 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN85990.1 - 1.9e-09 37.7 0.4 0.049 13.9 0.0 4.6 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KZN85990.1 - 1.1e-05 24.3 5.5 0.093 11.4 0.1 4.6 2 1 3 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KZN85990.1 - 0.0044 16.0 0.1 12 4.8 0.0 3.9 2 2 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KZN85990.1 - 0.005 15.4 0.0 1.3 7.5 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.12 KZN85990.1 - 0.016 15.1 0.5 20 5.3 0.0 4.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KZN85990.1 - 0.046 13.0 0.0 1.1 8.5 0.0 2.3 2 1 0 2 2 2 0 WD40-like domain TPR_12 PF13424.6 KZN85991.1 - 0.00027 21.1 10.9 0.0033 17.7 0.7 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KZN85991.1 - 0.003 17.3 11.0 0.016 15.0 0.3 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KZN85991.1 - 0.0092 15.8 1.3 0.0092 15.8 1.3 4.1 6 0 0 6 6 6 1 Tetratricopeptide repeat MIT PF04212.18 KZN85991.1 - 0.048 13.7 2.2 0.49 10.5 0.4 3.0 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 KZN85991.1 - 0.099 12.9 0.5 0.099 12.9 0.5 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KZN85991.1 - 5.7 7.3 25.9 1.6 9.0 0.2 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat SRAP PF02586.14 KZN85992.1 - 6.2e-79 264.6 0.0 8.7e-79 264.1 0.0 1.2 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Selenoprotein_S PF06936.11 KZN85992.1 - 1.8 8.3 7.1 0.16 11.8 2.5 1.5 2 0 0 2 2 2 0 Selenoprotein S (SelS) Med1 PF10744.9 KZN85994.1 - 3.3e-126 421.7 0.0 4.1e-126 421.4 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Dynein_heavy PF03028.15 KZN85994.1 - 0.087 12.9 0.2 0.16 12.1 0.2 1.3 1 0 0 1 1 1 0 Dynein heavy chain region D6 P-loop domain Gln-synt_C PF00120.24 KZN85995.1 - 5.7e-15 55.2 0.0 4.9e-12 45.5 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KZN85995.1 - 2.2e-12 46.5 0.0 4.1e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain MFS_1 PF07690.16 KZN85996.1 - 5.8e-32 111.0 30.2 5.8e-32 111.0 30.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Imm57 PF15596.6 KZN85996.1 - 0.00013 22.3 0.0 0.00024 21.4 0.0 1.4 1 0 0 1 1 1 1 Immunity protein 57 FPN1 PF06963.12 KZN85996.1 - 0.02 13.5 2.9 0.053 12.1 2.9 1.6 1 0 0 1 1 1 0 Ferroportin1 (FPN1) UNC-93 PF05978.16 KZN85996.1 - 0.28 10.9 6.2 0.36 10.5 4.8 1.8 1 1 1 2 2 2 0 Ion channel regulatory protein UNC-93 Disulph_isomer PF06491.11 KZN85998.1 - 0.18 11.9 0.8 0.37 10.9 0.8 1.4 1 0 0 1 1 1 0 Disulphide isomerase Sugar_tr PF00083.24 KZN85999.1 - 1e-109 367.4 23.0 1.3e-109 367.1 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN85999.1 - 2.7e-19 69.3 30.0 7.1e-15 54.8 5.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF3464 PF11947.8 KZN85999.1 - 0.58 9.9 1.8 1.3 8.7 1.8 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 zf-CCHC PF00098.23 KZN86000.1 - 1e-61 202.4 115.2 7.5e-07 28.9 1.8 13.4 13 0 0 13 13 13 13 Zinc knuckle zf-CCHC_3 PF13917.6 KZN86000.1 - 5.7e-12 45.4 87.1 0.0062 16.5 0.1 12.9 3 2 9 12 12 12 10 Zinc knuckle zf-CCHC_4 PF14392.6 KZN86000.1 - 2.3e-09 36.9 80.6 0.028 14.2 0.3 13.0 13 0 0 13 13 13 8 Zinc knuckle zf-CCHC_2 PF13696.6 KZN86000.1 - 0.0012 18.6 7.9 0.0077 16.0 0.9 12.5 13 0 0 13 13 13 9 Zinc knuckle zf-CCHC_6 PF15288.6 KZN86000.1 - 0.016 15.0 0.8 0.016 15.0 0.8 11.4 9 2 2 11 11 11 0 Zinc knuckle DUF846 PF05832.12 KZN86001.1 - 4.6e-47 159.6 9.4 5.7e-47 159.2 9.4 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) HpcH_HpaI PF03328.14 KZN86002.1 - 1.6e-39 135.3 0.1 1.5e-38 132.2 0.0 2.0 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KZN86002.1 - 1.1e-10 41.3 0.0 2.1e-05 23.8 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF1771 PF08590.10 KZN86003.1 - 3.2e-15 56.3 10.6 8.6e-15 54.9 10.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 KZN86003.1 - 6.4e-10 39.3 0.1 3.3e-09 37.0 0.1 2.3 2 0 0 2 2 2 1 Smr domain zf_CCCH_4 PF18345.1 KZN86003.1 - 9.4e-08 31.9 9.4 2.1e-05 24.4 1.2 2.9 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 KZN86003.1 - 2e-06 27.6 1.7 0.0045 16.9 0.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KZN86003.1 - 0.00016 21.8 2.3 0.22 11.8 0.0 2.4 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 KZN86003.1 - 0.00025 20.8 12.4 0.0046 16.7 1.5 3.1 2 1 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KZN86003.1 - 0.00033 21.0 6.1 0.18 12.3 1.0 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger CUE PF02845.16 KZN86003.1 - 0.15 11.8 1.6 0.44 10.3 0.1 2.4 2 0 0 2 2 2 0 CUE domain Torus PF16131.5 KZN86003.1 - 0.71 10.6 3.2 2.7 8.7 0.8 2.5 1 1 1 2 2 2 0 Torus domain SNARE_assoc PF09335.11 KZN86004.1 - 1.7e-11 44.7 5.4 1.7e-11 44.7 5.4 2.2 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF2070 PF09843.9 KZN86004.1 - 5 5.3 5.4 6.6 4.9 5.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Amino_oxidase PF01593.24 KZN86005.1 - 4.9e-84 283.2 0.0 2.5e-72 244.6 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SWIRM PF04433.17 KZN86005.1 - 3.3e-13 49.8 0.0 9.1e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.6 KZN86005.1 - 2.9e-07 30.6 0.1 6.4e-07 29.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.19 KZN86005.1 - 8.5e-05 22.9 0.9 0.00019 21.8 0.9 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box DAO PF01266.24 KZN86005.1 - 0.00059 19.5 0.4 0.0016 18.1 0.4 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KZN86005.1 - 0.012 14.9 0.2 0.11 11.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HMG_box_2 PF09011.10 KZN86005.1 - 0.033 14.8 1.2 0.071 13.7 1.2 1.6 1 0 0 1 1 1 0 HMG-box domain Pyr_redox_2 PF07992.14 KZN86006.1 - 8.3e-47 159.8 0.1 9.7e-47 159.6 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KZN86006.1 - 2.3e-18 66.5 0.1 3.9e-17 62.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KZN86006.1 - 1.4e-14 54.4 0.1 1.6e-12 47.8 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KZN86006.1 - 0.00013 22.4 0.1 0.015 15.7 0.0 3.0 2 2 1 3 3 3 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 KZN86006.1 - 0.00017 21.8 0.7 0.067 13.4 0.1 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KZN86006.1 - 0.00086 18.6 1.2 0.002 17.4 0.1 2.0 2 1 1 3 3 3 1 Thi4 family K_oxygenase PF13434.6 KZN86006.1 - 0.0056 15.9 0.1 0.35 10.0 0.0 3.0 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KZN86006.1 - 0.022 14.4 1.9 1.1 8.7 0.0 3.4 3 1 1 4 4 4 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KZN86006.1 - 0.027 13.7 1.0 9.3 5.4 0.0 2.8 2 1 1 3 3 3 0 FAD binding domain FAD_oxidored PF12831.7 KZN86006.1 - 0.052 12.9 0.2 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 KZN86006.1 - 0.086 11.9 5.7 5.3 6.0 0.1 3.8 3 2 2 5 5 5 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KZN86006.1 - 0.35 9.9 4.9 0.91 8.5 0.3 3.4 3 1 2 5 5 5 0 FAD binding domain PhoD PF09423.10 KZN86007.1 - 2.4e-06 26.8 0.0 5.9e-05 22.2 0.0 2.5 1 1 0 1 1 1 1 PhoD-like phosphatase Peptidase_S8 PF00082.22 KZN86008.1 - 2.7e-38 131.9 0.5 4.3e-38 131.3 0.5 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KZN86008.1 - 1e-26 92.8 0.1 2.1e-26 91.8 0.1 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 KZN86008.1 - 0.17 12.6 0.0 0.39 11.5 0.0 1.6 1 0 0 1 1 1 0 Peptidase S8 pro-domain PX PF00787.24 KZN86009.1 - 4.8e-19 68.4 0.2 9.1e-19 67.5 0.2 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KZN86009.1 - 2.7e-15 56.6 5.9 1.9e-07 30.9 0.6 2.1 2 0 0 2 2 2 2 Vps5 C terminal like Sec34 PF04136.15 KZN86009.1 - 0.005 16.7 0.1 0.014 15.3 0.0 1.7 2 1 0 2 2 2 1 Sec34-like family FlaC_arch PF05377.11 KZN86009.1 - 0.088 13.2 1.0 16 6.0 0.0 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) BAR PF03114.18 KZN86009.1 - 0.25 11.0 5.9 0.95 9.1 2.3 2.4 2 1 0 2 2 2 0 BAR domain Syntaxin-6_N PF09177.11 KZN86009.1 - 0.26 11.8 3.4 7.9 7.1 0.1 3.2 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 KZN86009.1 - 0.48 10.5 2.2 11 6.1 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Occludin_ELL PF07303.13 KZN86009.1 - 0.74 10.6 4.6 1.7 9.4 0.0 3.0 3 0 0 3 3 3 0 Occludin homology domain Prefoldin_2 PF01920.20 KZN86009.1 - 1.2 9.1 3.9 3.8 7.5 0.2 2.4 2 0 0 2 2 2 0 Prefoldin subunit FAD_binding_3 PF01494.19 KZN86010.1 - 4e-21 75.7 0.0 1.3e-17 64.1 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain SE PF08491.10 KZN86010.1 - 6e-06 25.5 0.0 1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.12 KZN86010.1 - 0.0092 15.1 0.1 0.032 13.3 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KZN86010.1 - 0.012 14.8 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KZN86010.1 - 0.02 14.9 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KZN86010.1 - 0.091 11.6 0.1 1.1 8.0 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 KZN86010.1 - 0.11 11.2 0.1 0.15 10.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein K_oxygenase PF13434.6 KZN86010.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KZN86010.1 - 0.2 10.9 0.0 0.37 10.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family tRNA-synt_His PF13393.6 KZN86011.1 - 8.4e-35 120.5 0.0 9.1e-29 100.7 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KZN86011.1 - 5.9e-10 39.2 0.0 1.1e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KZN86011.1 - 3.6e-05 23.8 0.0 0.0001 22.3 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon2 PF12745.7 KZN86011.1 - 0.04 13.4 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs UCH PF00443.29 KZN86012.1 - 1.3e-56 192.0 0.1 2.6e-56 191.0 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KZN86012.1 - 5.2e-29 101.9 0.1 1.9e-28 100.0 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KZN86012.1 - 0.0026 17.3 4.5 0.052 13.0 2.6 2.8 3 0 0 3 3 3 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Yos1 PF08571.10 KZN86013.1 - 2.5e-36 123.8 0.7 2.8e-36 123.6 0.7 1.0 1 0 0 1 1 1 1 Yos1-like Glyco_transf_22 PF03901.17 KZN86014.1 - 5.5e-43 147.7 13.4 6.8e-43 147.5 13.4 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Dynamitin PF04912.14 KZN86015.1 - 1.3e-74 251.9 8.7 2.4e-73 247.7 8.7 2.0 1 1 0 1 1 1 1 Dynamitin Jnk-SapK_ap_N PF09744.9 KZN86015.1 - 2.8e-05 24.4 8.1 0.0034 17.6 0.3 2.9 3 0 0 3 3 3 2 JNK_SAPK-associated protein-1 TPR_MLP1_2 PF07926.12 KZN86015.1 - 0.012 15.6 2.1 0.012 15.6 2.1 3.4 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 KZN86015.1 - 0.014 15.4 0.1 0.17 12.0 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) SlyX PF04102.12 KZN86015.1 - 0.017 15.7 4.8 0.99 10.1 0.2 4.2 5 0 0 5 5 4 0 SlyX DHR10 PF18595.1 KZN86015.1 - 0.019 15.1 0.4 0.019 15.1 0.4 3.2 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain DUF2408 PF10303.9 KZN86015.1 - 0.025 15.1 0.4 2.6 8.6 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) Spectrin PF00435.21 KZN86015.1 - 0.036 14.5 4.2 1.2 9.7 0.5 3.3 3 0 0 3 3 3 0 Spectrin repeat Spc24 PF08286.11 KZN86015.1 - 0.042 14.1 4.2 0.58 10.4 0.3 3.0 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Fmp27_WPPW PF10359.9 KZN86015.1 - 0.051 12.4 0.7 3.3 6.5 0.2 2.3 2 1 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Spc7 PF08317.11 KZN86015.1 - 0.062 12.2 4.6 0.14 11.0 0.4 2.5 2 1 0 2 2 2 0 Spc7 kinetochore protein CCDC32 PF14989.6 KZN86015.1 - 0.07 13.1 0.9 0.86 9.6 0.2 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing 32 Laminin_II PF06009.12 KZN86015.1 - 0.094 12.7 0.3 0.094 12.7 0.3 2.9 2 1 2 4 4 4 0 Laminin Domain II PhaP_Bmeg PF09602.10 KZN86015.1 - 0.14 12.1 0.3 2.6 8.0 0.1 2.4 2 1 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) FapA PF03961.13 KZN86015.1 - 0.17 10.5 0.0 0.8 8.2 0.0 1.8 2 0 0 2 2 2 0 Flagellar Assembly Protein A MbeD_MobD PF04899.12 KZN86015.1 - 0.33 11.1 3.7 1.8 8.7 0.5 3.2 3 0 0 3 3 3 0 MbeD/MobD like DUF4618 PF15397.6 KZN86015.1 - 0.35 10.3 2.1 9.5 5.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Prefoldin_2 PF01920.20 KZN86015.1 - 0.38 10.7 6.4 0.57 10.2 0.8 2.7 3 0 0 3 3 3 0 Prefoldin subunit DUF4200 PF13863.6 KZN86015.1 - 0.38 11.1 0.1 0.38 11.1 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Golgin_A5 PF09787.9 KZN86015.1 - 0.8 9.1 5.1 1.5 8.2 0.7 2.4 2 1 0 2 2 2 0 Golgin subfamily A member 5 MscS_porin PF12795.7 KZN86015.1 - 1.1 8.7 7.4 3.1 7.3 0.2 3.4 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain DUF2203 PF09969.9 KZN86015.1 - 1.6 9.5 6.4 2.1 9.1 0.2 3.2 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Rho_Binding PF08912.11 KZN86015.1 - 1.7 9.5 4.9 1.9 9.3 0.3 2.8 3 0 0 3 3 3 0 Rho Binding Prefoldin PF02996.17 KZN86015.1 - 1.9 8.4 6.9 0.61 10.0 0.5 2.9 3 1 0 3 3 2 0 Prefoldin subunit ZapB PF06005.12 KZN86015.1 - 3.7 8.1 5.9 34 5.0 1.1 3.4 3 0 0 3 3 3 0 Cell division protein ZapB DivIC PF04977.15 KZN86015.1 - 4 7.3 9.2 4 7.3 0.1 3.6 3 2 0 3 3 3 0 Septum formation initiator Tmemb_cc2 PF10267.9 KZN86015.1 - 5.2 6.1 7.5 1.3e+02 1.5 7.4 2.3 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Aldedh PF00171.22 KZN86017.1 - 2.2e-136 455.0 0.5 2.7e-136 454.8 0.5 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Calreticulin PF00262.18 KZN86018.1 - 1.9e-169 563.3 15.7 2.5e-169 562.9 15.7 1.1 1 0 0 1 1 1 1 Calreticulin family DUF1911 PF08929.10 KZN86018.1 - 0.12 13.2 0.0 0.27 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1911) Cnn_1N PF07989.11 KZN86018.1 - 0.17 12.1 0.1 0.36 11.0 0.1 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Aldolase_II PF00596.21 KZN86019.1 - 2.6e-42 144.9 0.0 3.1e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Vps5 PF09325.10 KZN86020.1 - 2.2e-88 295.8 4.8 2.2e-88 295.8 4.8 1.4 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 KZN86020.1 - 5.5e-24 84.3 0.2 1.2e-23 83.2 0.0 1.7 2 0 0 2 2 2 1 PX domain BAR_3 PF16746.5 KZN86020.1 - 0.0023 17.7 6.6 0.1 12.3 1.9 2.2 1 1 1 2 2 2 2 BAR domain of APPL family BAR_3_WASP_bdg PF10456.9 KZN86020.1 - 0.02 14.3 0.8 0.41 10.1 0.7 2.1 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein DUF3450 PF11932.8 KZN86020.1 - 0.34 10.2 8.0 0.073 12.4 4.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) IER PF05760.12 KZN86021.1 - 0.0045 17.3 0.5 0.0061 16.9 0.5 1.4 1 1 0 1 1 1 1 Immediate early response protein (IER) DUF3275 PF11679.8 KZN86021.1 - 0.12 12.4 2.9 0.12 12.4 2.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) Flavin_Reduct PF01613.18 KZN86022.1 - 4.8e-28 98.1 0.0 7.4e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Flavin reductase like domain DUF4505 PF14956.6 KZN86022.1 - 0.029 14.1 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4505) Nas2_N PF18265.1 KZN86023.1 - 0.11 12.4 3.9 0.11 12.4 0.7 2.4 2 0 0 2 2 2 0 Nas2 N_terminal domain NUDIX PF00293.28 KZN86024.1 - 1.9e-14 53.8 0.0 2.9e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain 4HBT_2 PF13279.6 KZN86025.1 - 9.7e-10 39.0 0.0 1.6e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4080 PF13311.6 KZN86025.1 - 0.073 13.3 0.1 0.1 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4080) Complex1_LYR_2 PF13233.6 KZN86026.1 - 1.4e-06 28.9 0.2 1.6e-06 28.7 0.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KZN86026.1 - 4.6e-06 26.6 0.7 6e-06 26.2 0.7 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Methyltransf_25 PF13649.6 KZN86027.1 - 3e-08 34.2 0.0 5.5e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN86027.1 - 3e-06 27.8 0.0 5.3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN86027.1 - 0.0015 18.4 0.0 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KZN86027.1 - 0.0026 17.1 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Exo_endo_phos PF03372.23 KZN86028.1 - 6.3e-17 61.9 0.0 3.6e-16 59.4 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 KZN86028.1 - 2e-10 40.8 8.5 4.4e-06 26.9 1.3 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KZN86028.1 - 6.1e-10 38.7 5.8 2.5e-08 33.6 6.4 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 KZN86028.1 - 0.13 12.9 6.0 9.6 7.2 0.1 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat APH PF01636.23 KZN86029.1 - 1e-11 45.2 0.2 2.8e-11 43.8 0.2 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN86029.1 - 0.012 15.3 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase YfiO PF13525.6 KZN86029.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein Mito_carr PF00153.27 KZN86030.1 - 4.5e-30 103.4 1.9 1.2e-14 53.9 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KZN86030.1 - 0.061 12.5 0.1 0.12 11.5 0.1 1.6 1 0 0 1 1 1 0 Gammaproteobacterial serine protease FMN_red PF03358.15 KZN86032.1 - 6.7e-25 87.6 0.0 1e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KZN86032.1 - 0.04 13.6 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin-like fold PGA2 PF07543.12 KZN86032.1 - 0.13 12.3 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 Hydrolase_4 PF12146.8 KZN86033.1 - 1.4e-45 155.5 0.0 1.7e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KZN86033.1 - 9.8e-10 39.4 0.3 2e-09 38.4 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KZN86033.1 - 1.8e-07 31.1 0.5 3.6e-07 30.1 0.2 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 KZN86033.1 - 0.0027 17.3 0.0 0.054 13.0 0.0 2.5 2 1 1 3 3 3 1 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 KZN86033.1 - 0.0089 15.0 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S10 PF00450.22 KZN86033.1 - 0.11 11.8 0.0 0.54 9.6 0.0 1.8 2 0 0 2 2 2 0 Serine carboxypeptidase Peptidase_S9 PF00326.21 KZN86033.1 - 0.12 11.9 0.0 8.4 5.8 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family GCD14 PF08704.10 KZN86034.1 - 6.7e-09 35.8 0.0 0.00066 19.4 0.0 2.3 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit GCD14_N PF14801.6 KZN86034.1 - 2.2e-05 24.2 0.1 4.6e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_25 PF13649.6 KZN86034.1 - 0.018 15.8 0.0 11 6.7 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Metallophos PF00149.28 KZN86035.1 - 6.8e-16 59.4 0.3 9.5e-16 58.9 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KZN86035.1 - 8.7e-07 29.3 0.1 1.6e-05 25.2 0.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Epimerase_2 PF02350.19 KZN86035.1 - 0.09 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase NAD_binding_1 PF00175.21 KZN86036.1 - 9.6e-07 29.4 0.0 0.04 14.6 0.0 3.0 3 0 0 3 3 3 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KZN86036.1 - 7.5e-06 26.1 0.0 0.00011 22.4 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain SopE_GEF PF07487.13 KZN86036.1 - 0.13 12.4 0.1 0.23 11.6 0.1 1.3 1 0 0 1 1 1 0 SopE GEF domain GATA PF00320.27 KZN86039.1 - 1e-15 57.0 5.6 2e-15 56.1 5.6 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 KZN86039.1 - 3.6e-10 40.0 0.0 6.7e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 KZN86039.1 - 3.6e-08 33.4 0.5 2e-07 31.0 0.0 2.3 3 0 0 3 3 3 1 PAS fold PAS_4 PF08448.10 KZN86039.1 - 6e-08 32.9 0.0 1.6e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KZN86039.1 - 6.6e-06 26.3 0.0 1.7e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 KZN86039.1 - 0.0032 17.5 0.0 0.0068 16.4 0.0 1.5 1 0 0 1 1 1 1 PAS domain Nudix_N_2 PF14803.6 KZN86039.1 - 3.1 7.8 5.4 2.1 8.4 1.8 2.4 1 1 1 2 2 2 0 Nudix N-terminal AAA_23 PF13476.6 KZN86040.1 - 8.9e-37 127.5 2.4 8.9e-37 127.5 2.4 8.1 3 2 1 4 4 4 1 AAA domain SMC_N PF02463.19 KZN86040.1 - 2.2e-16 60.0 5.5 2.4e-09 37.0 3.4 3.6 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KZN86040.1 - 6.9e-10 39.2 1.8 6.9e-10 39.2 1.8 6.0 1 1 1 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 KZN86040.1 - 8.1e-08 32.4 15.6 0.0021 17.9 0.0 4.6 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KZN86040.1 - 1.3e-06 28.5 0.0 5.6e-06 26.5 0.0 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KZN86040.1 - 0.00071 19.3 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain KNOX2 PF03791.13 KZN86040.1 - 0.0067 15.9 0.1 0.29 10.7 0.1 3.2 2 0 0 2 2 2 1 KNOX2 domain AAA_16 PF13191.6 KZN86040.1 - 0.061 13.7 0.0 0.061 13.7 0.0 6.0 4 3 1 5 5 5 0 AAA ATPase domain L51_S25_CI-B8 PF05047.16 KZN86041.1 - 5.6e-20 71.0 0.0 1.1e-19 70.1 0.0 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DNA_pol3_theta PF06440.11 KZN86041.1 - 0.066 12.9 0.2 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase III, theta subunit tRNA-synt_1 PF00133.22 KZN86042.1 - 1.2e-37 129.5 0.0 1.1e-26 93.3 0.0 2.9 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KZN86042.1 - 1.9e-17 63.1 0.1 1.7e-10 40.3 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KZN86042.1 - 5e-16 59.0 0.0 1.7e-15 57.3 0.0 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KZN86042.1 - 3.7e-07 29.8 0.0 7.6e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 KZN86042.1 - 0.0077 15.2 0.0 0.25 10.2 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (K) Aminotran_1_2 PF00155.21 KZN86043.1 - 8.8e-39 133.7 0.0 1.1e-38 133.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KZN86043.1 - 0.00024 20.5 0.0 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_3 PF00202.21 KZN86043.1 - 0.049 12.3 0.0 0.14 10.8 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class-III MMR_HSR1 PF01926.23 KZN86044.1 - 9.6e-06 25.7 0.0 0.03 14.4 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase ATPase-cat_bd PF12156.8 KZN86044.1 - 0.0042 17.8 0.2 0.0084 16.8 0.2 1.5 1 0 0 1 1 1 1 Putative metal-binding domain of cation transport ATPase RsgA_GTPase PF03193.16 KZN86044.1 - 0.0048 16.8 0.0 0.012 15.5 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KZN86044.1 - 0.071 13.2 0.1 0.92 9.6 0.0 2.6 3 0 0 3 3 3 0 Dynamin family Spore_IV_A PF09547.10 KZN86044.1 - 0.21 10.5 0.0 0.3 10.0 0.0 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) Sde2_N_Ubi PF13019.6 KZN86045.1 - 1.4e-67 226.7 1.0 2.3e-67 225.9 1.0 1.4 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain S10_plectin PF03501.15 KZN86046.1 - 6e-42 141.6 0.1 7.3e-42 141.4 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Rio2_N PF09202.11 KZN86046.1 - 0.037 14.3 0.3 0.065 13.5 0.1 1.5 1 1 1 2 2 2 0 Rio2, N-terminal TrmB PF01978.19 KZN86046.1 - 0.17 11.8 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Peptidase_M20 PF01546.28 KZN86047.1 - 8.1e-29 100.8 0.2 1.1e-28 100.4 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KZN86047.1 - 1.9e-06 27.7 0.0 3.6e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KZN86047.1 - 0.0048 16.6 0.1 0.45 10.2 0.0 2.3 2 0 0 2 2 2 2 Peptidase family M28 MAS20 PF02064.15 KZN86049.1 - 0.066 13.3 0.8 0.13 12.3 0.8 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor ATG2_CAD PF13329.6 KZN86050.1 - 3.2e-45 153.6 0.0 1.5e-44 151.4 0.0 2.3 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 KZN86050.1 - 4.8e-29 100.6 0.0 1.2e-28 99.3 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain A_deaminase PF00962.22 KZN86051.1 - 1.3e-21 77.3 0.0 2e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase PIP5K PF01504.18 KZN86052.1 - 4e-40 137.8 0.0 1.1e-37 129.8 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase MFS_1 PF07690.16 KZN86053.1 - 2.2e-16 59.7 45.9 2.2e-16 59.7 45.9 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KZN86053.1 - 1.2e-07 30.6 17.3 4.3e-07 28.8 17.3 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SesA PF17107.5 KZN86054.1 - 1.9e-05 24.8 0.9 4.3e-05 23.7 0.9 1.6 1 1 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases oligo_HPY PF08352.12 KZN86054.1 - 0.077 13.5 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 Oligopeptide/dipeptide transporter, C-terminal region Retrotran_gag_2 PF14223.6 KZN86055.1 - 0.019 14.7 0.2 0.063 12.9 0.0 1.9 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Nucleos_tra2_C PF07662.13 KZN86056.1 - 5e-72 242.1 0.1 5e-72 242.1 0.1 3.1 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KZN86056.1 - 7.4e-23 80.9 6.2 7.4e-23 80.9 6.2 2.9 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus UQ_con PF00179.26 KZN86057.1 - 1.2e-46 157.9 0.0 1.6e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KZN86057.1 - 0.00044 20.5 0.0 0.00053 20.2 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KZN86057.1 - 0.00047 19.9 0.0 0.00071 19.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KZN86057.1 - 0.00095 19.0 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 UEV domain Pkinase PF00069.25 KZN86058.1 - 8.5e-60 202.3 0.0 1.1e-59 202.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN86058.1 - 2e-24 86.3 0.0 2.7e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KZN86058.1 - 2.1e-08 33.9 0.0 2.9e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KZN86058.1 - 0.0016 18.4 0.1 1.1 9.1 0.0 2.4 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KZN86058.1 - 0.082 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.7 KZN86059.1 - 3.9e-05 23.4 0.0 8.2e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN86059.1 - 0.00073 19.3 0.1 0.0014 18.5 0.1 1.5 1 0 0 1 1 1 1 F-box domain DHBP_synthase PF00926.19 KZN86060.1 - 7.2e-81 270.3 0.0 8.4e-81 270.1 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase TFA2_Winged_2 PF18121.1 KZN86061.1 - 1.4e-23 82.4 0.3 3.3e-23 81.1 0.3 1.7 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 KZN86061.1 - 4e-21 75.1 0.1 1.9e-20 72.9 0.0 2.2 2 1 0 2 2 2 1 TFIIE beta subunit core domain RNase_E_G PF10150.9 KZN86061.1 - 0.15 11.5 0.1 0.22 10.9 0.1 1.2 1 0 0 1 1 1 0 Ribonuclease E/G family DUF3446 PF11928.8 KZN86061.1 - 0.2 12.0 4.6 0.36 11.2 4.6 1.4 1 0 0 1 1 1 0 Early growth response N-terminal domain TPR_MLP1_2 PF07926.12 KZN86062.1 - 3.3e-37 127.4 27.8 3.3e-37 127.4 27.8 17.4 7 5 9 16 16 16 5 TPR/MLP1/MLP2-like protein KASH_CCD PF14662.6 KZN86062.1 - 0.00013 21.8 19.6 0.00013 21.8 19.6 13.3 6 4 5 12 12 12 2 Coiled-coil region of CCDC155 or KASH APG6_N PF17675.1 KZN86062.1 - 0.0017 18.9 15.0 0.0017 18.9 15.0 18.5 5 3 11 18 18 18 3 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 KZN86062.1 - 0.0029 17.6 19.6 0.0029 17.6 19.6 15.9 5 3 10 18 18 18 7 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0242 PF06785.11 KZN86062.1 - 0.0044 17.2 7.6 0.0044 17.2 7.6 14.7 7 4 6 14 14 14 1 Uncharacterised protein family (UPF0242) N-terminus ParE_toxin PF05016.15 KZN86062.1 - 0.086 13.5 0.1 0.086 13.5 0.1 5.4 5 0 0 5 5 5 0 ParE toxin of type II toxin-antitoxin system, parDE Scm3 PF10384.9 KZN86062.1 - 0.12 12.1 1.9 0.49 10.2 0.2 3.2 2 0 0 2 2 2 0 Centromere protein Scm3 AhpC-TSA PF00578.21 KZN86062.1 - 0.28 11.1 1.3 0.82 9.6 0.1 2.4 2 0 0 2 2 2 0 AhpC/TSA family Hexapep PF00132.24 KZN86063.1 - 4e-06 26.3 6.5 0.017 14.8 0.2 4.2 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Acid_PPase PF12689.7 KZN86064.1 - 7.9e-70 234.1 0.0 9.2e-70 233.9 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase AA_permease PF00324.21 KZN86066.1 - 9e-106 354.3 32.0 1.1e-105 354.0 32.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KZN86066.1 - 3.9e-25 88.5 36.2 5e-25 88.2 36.2 1.2 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.22 KZN86067.1 - 3.1e-52 177.9 0.0 4.7e-39 134.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 adh_short_C2 PF13561.6 KZN86068.1 - 4.4e-36 124.6 0.0 4.2e-35 121.4 0.0 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN86068.1 - 6.5e-35 120.4 0.0 1.1e-34 119.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN86068.1 - 3.8e-10 39.9 0.6 7.2e-09 35.8 0.1 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KZN86068.1 - 0.074 12.5 0.0 7.1 6.0 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Ribosomal_S6e PF01092.19 KZN86068.1 - 0.16 11.9 0.0 1.6 8.7 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S6e Amidase PF01425.21 KZN86069.1 - 3.9e-74 250.2 1.2 9e-74 249.0 1.2 1.5 1 1 0 1 1 1 1 Amidase Abhydrolase_1 PF00561.20 KZN86070.1 - 8.3e-17 61.7 0.3 1.7e-16 60.7 0.3 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KZN86070.1 - 1.4e-07 32.4 0.0 1.9e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KZN86070.1 - 0.00067 19.0 0.0 0.0039 16.5 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 KZN86070.1 - 0.0059 16.3 0.1 0.0065 16.1 0.1 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 KZN86070.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase MFS_1 PF07690.16 KZN86071.1 - 9.1e-31 107.1 69.7 3.9e-30 105.0 51.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribonuc_L-PSP PF01042.21 KZN86072.1 - 2.7e-17 62.9 0.0 3.6e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP NOGCT PF08155.11 KZN86072.1 - 0.093 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 NOGCT (NUC087) domain Fungal_trans PF04082.18 KZN86073.1 - 4.9e-27 94.6 0.2 8.2e-27 93.9 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain LRR_6 PF13516.6 KZN86074.1 - 0.0055 16.7 0.9 1.5 9.0 0.0 3.8 4 0 0 4 4 4 1 Leucine Rich repeat REV PF00424.18 KZN86074.1 - 0.059 13.4 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Sec63 PF02889.16 KZN86075.1 - 5e-36 124.2 0.2 7.4e-36 123.6 0.2 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KZN86075.1 - 5.6e-26 91.4 0.1 1e-25 90.5 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KZN86075.1 - 1.4e-13 51.2 0.0 2.9e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KZN86075.1 - 2e-07 31.3 0.0 9.5e-07 29.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KZN86075.1 - 0.00023 21.5 0.0 0.00069 19.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KZN86075.1 - 0.00063 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KZN86075.1 - 0.0017 18.7 0.0 0.0042 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 KZN86075.1 - 0.005 17.4 0.0 0.014 16.0 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain UvrD-helicase PF00580.21 KZN86075.1 - 0.03 13.9 0.0 0.03 13.9 0.0 2.3 2 1 0 2 2 1 0 UvrD/REP helicase N-terminal domain T2SSE PF00437.20 KZN86075.1 - 0.037 13.1 0.0 0.093 11.8 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Helicase_RecD PF05127.14 KZN86075.1 - 0.13 12.1 0.0 0.35 10.7 0.0 1.8 1 0 0 1 1 1 0 Helicase Nuc_sug_transp PF04142.15 KZN86076.1 - 5.5e-84 282.0 0.7 6.9e-84 281.7 0.7 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 KZN86076.1 - 0.00019 20.7 2.2 0.0017 17.6 0.3 2.1 2 0 0 2 2 2 1 UAA transporter family EamA PF00892.20 KZN86076.1 - 0.011 15.9 9.5 0.011 15.9 9.5 2.8 2 2 0 2 2 2 0 EamA-like transporter family TPT PF03151.16 KZN86076.1 - 0.014 14.8 6.5 0.16 11.2 0.5 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family EmrE PF13536.6 KZN86076.1 - 0.039 13.5 0.1 0.039 13.5 0.1 2.8 3 0 0 3 3 3 0 Putative multidrug resistance efflux transporter TMEM234 PF10639.9 KZN86076.1 - 0.12 12.5 3.8 0.047 13.7 1.0 1.9 2 0 0 2 2 2 0 Putative transmembrane family 234 HORMA PF02301.18 KZN86078.1 - 1.7e-41 142.1 0.0 2.9e-41 141.4 0.0 1.4 1 0 0 1 1 1 1 HORMA domain PHD PF00628.29 KZN86078.1 - 0.0026 17.6 8.5 0.0053 16.6 8.5 1.5 1 0 0 1 1 1 1 PHD-finger WD40 PF00400.32 KZN86079.1 - 2.1e-42 142.3 16.3 1e-05 26.2 0.6 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 KZN86079.1 - 1.4e-08 34.5 0.2 2.6e-08 33.6 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN86079.1 - 1.3e-07 31.3 0.1 3.4e-07 30.0 0.1 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KZN86079.1 - 5.1e-06 26.7 2.0 2.3 8.6 0.0 4.9 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 KZN86079.1 - 0.01 15.7 0.3 0.027 14.4 0.1 1.8 2 0 0 2 2 2 0 F-box Nup160 PF11715.8 KZN86079.1 - 0.035 12.8 7.8 5.6 5.5 0.1 5.0 4 1 2 6 6 6 0 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KZN86079.1 - 1.9 7.3 4.1 14 4.5 0.0 3.7 3 2 2 5 5 5 0 Partner and localizer of BRCA2 WD40 domain MMR_HSR1 PF01926.23 KZN86080.1 - 8.1e-19 67.8 0.0 1.2e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KZN86080.1 - 1.6e-06 28.3 0.0 0.00024 21.2 0.0 2.2 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.18 KZN86080.1 - 0.00011 21.8 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KZN86080.1 - 0.00013 21.9 0.1 0.005 16.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 KZN86080.1 - 0.00024 20.5 0.0 0.00035 20.0 0.0 1.1 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 KZN86080.1 - 0.00084 18.9 0.0 0.0059 16.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KZN86080.1 - 0.0013 18.1 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KZN86080.1 - 0.037 14.6 0.1 0.064 13.8 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KZN86080.1 - 0.048 13.4 0.0 0.099 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 KZN86080.1 - 0.091 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Clat_adaptor_s PF01217.20 KZN86081.1 - 4e-43 146.8 0.0 8.3e-43 145.7 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_L7Ae PF01248.26 KZN86082.1 - 2.6e-23 81.6 0.6 4.1e-23 80.9 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KZN86082.1 - 0.00041 20.4 0.0 0.00063 19.8 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 HEAT_2 PF13646.6 KZN86083.1 - 2e-06 28.1 1.7 0.49 10.8 0.0 4.6 3 1 1 4 4 4 2 HEAT repeats CLASP_N PF12348.8 KZN86083.1 - 2.4e-06 27.3 0.0 7.2e-05 22.5 0.0 2.6 2 0 0 2 2 2 1 CLASP N terminal HEAT PF02985.22 KZN86083.1 - 3e-06 27.0 1.1 5.6 7.5 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 KZN86083.1 - 4.5e-05 23.5 0.1 0.0098 15.9 0.1 2.7 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 TAN PF11640.8 KZN86083.1 - 0.013 15.6 1.1 0.043 13.9 0.1 2.4 2 1 0 2 2 2 0 Telomere-length maintenance and DNA damage repair ADIP PF11559.8 KZN86083.1 - 0.099 12.7 12.5 0.28 11.3 12.5 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Syntaxin PF00804.25 KZN86083.1 - 0.12 12.1 7.6 0.28 10.8 7.6 1.6 1 0 0 1 1 1 0 Syntaxin DUF1722 PF08349.11 KZN86083.1 - 0.14 12.4 0.3 7.4 6.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1722) Golgin_A5 PF09787.9 KZN86083.1 - 0.15 11.5 10.8 0.31 10.4 10.8 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF812 PF05667.11 KZN86083.1 - 0.37 9.6 10.6 0.67 8.8 2.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF812) FliD_N PF02465.18 KZN86083.1 - 0.37 11.5 3.2 1.6 9.5 3.2 2.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus UPF0242 PF06785.11 KZN86083.1 - 0.84 9.7 6.6 2.3 8.3 6.6 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus COG5 PF10392.9 KZN86083.1 - 0.98 9.6 7.8 0.35 11.0 4.7 1.8 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Spc7 PF08317.11 KZN86083.1 - 1.1 8.1 11.6 2.4 6.9 11.6 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF724 PF05266.14 KZN86083.1 - 1.2 8.9 9.8 4.2 7.1 9.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF724) HIP1_clath_bdg PF16515.5 KZN86083.1 - 4.8 7.9 16.3 3.8 8.2 3.8 3.0 3 0 0 3 3 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 APG6_N PF17675.1 KZN86083.1 - 5 7.7 18.6 0.56 10.7 13.0 2.3 2 1 1 3 3 2 0 Apg6 coiled-coil region DUF3450 PF11932.8 KZN86083.1 - 6.4 6.0 13.1 52 3.0 13.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4407 PF14362.6 KZN86083.1 - 7.1 5.9 12.3 0.8 9.0 7.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HAUS-augmin3 PF14932.6 KZN86083.1 - 9.5 5.7 10.5 64 3.0 9.3 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 WD40 PF00400.32 KZN86084.1 - 6.7e-52 172.3 21.1 6.4e-09 36.3 0.9 8.8 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN86084.1 - 1.1e-12 48.1 0.0 0.015 15.6 0.0 4.8 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KZN86084.1 - 1.6e-08 33.7 0.6 0.011 14.4 0.0 4.1 5 1 1 6 6 6 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KZN86084.1 - 0.0092 14.8 0.1 2.1 7.0 0.0 3.6 2 1 1 3 3 3 1 Nup133 N terminal like Ribosomal_S17 PF00366.20 KZN86085.1 - 7.2e-15 54.8 0.5 1.8e-14 53.6 0.5 1.7 1 0 0 1 1 1 1 Ribosomal protein S17 Ferlin_C PF16165.5 KZN86085.1 - 0.41 10.6 2.1 0.6 10.0 2.1 1.2 1 0 0 1 1 1 0 Ferlin C-terminus Glyco_transf_20 PF00982.21 KZN86086.1 - 1.2e-201 670.5 0.0 1.4e-201 670.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 KZN86086.1 - 0.013 15.2 0.1 0.032 13.9 0.1 1.6 1 0 0 1 1 1 0 Starch synthase catalytic domain BLACT_WH PF17778.1 KZN86087.1 - 2.3e-19 69.1 0.0 4.4e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 KZN86087.1 - 1.5e-09 38.2 6.5 9.7e-05 22.4 0.4 2.3 1 1 1 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KZN86087.1 - 0.00015 21.4 1.0 0.00035 20.1 1.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Aconitase PF00330.20 KZN86088.1 - 2.2e-149 498.4 0.0 2.8e-149 498.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KZN86088.1 - 1.9e-43 147.9 0.0 4.1e-43 146.8 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.8 KZN86089.1 - 1e-09 38.4 5.4 1.7e-09 37.7 5.4 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KZN86089.1 - 0.00027 21.2 2.5 0.00046 20.5 2.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 KZN86089.1 - 0.00063 19.5 1.0 0.0011 18.6 1.0 1.4 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_4 PF13894.6 KZN86089.1 - 0.0015 19.2 0.9 0.0035 18.0 0.9 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KZN86089.1 - 0.0077 16.2 1.9 0.012 15.6 1.9 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KZN86089.1 - 0.016 15.5 0.3 0.025 14.9 0.3 1.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KZN86089.1 - 0.053 14.0 1.0 0.12 12.9 1.0 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-DBF PF07535.12 KZN86089.1 - 0.061 13.4 1.9 1.2 9.3 1.0 2.2 2 0 0 2 2 2 0 DBF zinc finger Mito_carr PF00153.27 KZN86090.1 - 1.1e-48 163.1 0.6 2.6e-20 72.2 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 KZN86092.1 - 2.5e-13 50.0 0.0 3.6e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN86092.1 - 4.1e-09 36.1 0.0 8.3e-09 35.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KZN86092.1 - 3.2e-06 27.3 0.3 7.5e-06 26.0 0.3 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KZN86092.1 - 3.5e-05 23.5 0.0 5.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KZN86092.1 - 0.00026 20.4 0.1 0.00036 20.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KZN86092.1 - 0.0032 17.1 0.1 0.0069 16.0 0.1 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 KZN86092.1 - 0.098 11.4 0.1 0.13 11.0 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase Rad54_N PF08658.10 KZN86094.1 - 1.9e-55 187.8 1.0 1.2e-54 185.2 1.1 2.1 2 0 0 2 2 2 1 Rad54 N terminal SNF2_N PF00176.23 KZN86094.1 - 9.9e-55 185.6 0.0 1.5e-54 185.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KZN86094.1 - 1.3e-14 54.5 0.0 3.1e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KZN86094.1 - 6.6e-07 29.5 0.0 1.4e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KZN86094.1 - 0.0011 18.2 0.0 0.0058 15.8 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Vac14_Fig4_bd PF11916.8 KZN86095.1 - 2.5e-80 268.3 8.0 2.5e-80 268.3 8.0 2.1 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KZN86095.1 - 1.9e-42 143.8 0.0 4.4e-40 136.2 0.0 3.9 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KZN86095.1 - 2.5e-09 37.4 2.0 0.026 15.0 0.0 5.6 4 1 1 5 5 5 2 HEAT-like repeat HEAT PF02985.22 KZN86095.1 - 3.2e-07 30.0 1.8 0.0011 19.1 0.0 4.8 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 KZN86095.1 - 3.3e-05 24.2 2.3 1 9.8 0.0 5.0 5 1 0 5 5 5 1 HEAT repeats Cnd1 PF12717.7 KZN86095.1 - 0.0001 22.4 2.0 0.076 13.1 0.4 3.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 KZN86095.1 - 0.0053 16.8 0.1 16 5.7 0.0 5.2 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat DUF3385 PF11865.8 KZN86095.1 - 0.018 14.9 0.2 6.9 6.6 0.0 4.1 3 1 0 3 3 3 0 Domain of unknown function (DUF3385) DUF4630 PF15443.6 KZN86095.1 - 0.14 12.3 4.7 0.17 12.0 2.6 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4630) TauD PF02668.16 KZN86098.1 - 1.9e-16 60.7 0.2 2.6e-16 60.2 0.2 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KZN86098.1 - 1.3e-06 27.8 0.0 2.8e-06 26.7 0.0 1.5 2 0 0 2 2 2 1 CsiD Glyco_hydro_15 PF00723.21 KZN86100.1 - 9.9e-105 350.9 0.1 1.1e-104 350.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Dehydrin PF00257.19 KZN86101.1 - 0.0023 18.5 6.1 0.003 18.1 6.1 1.2 1 0 0 1 1 1 1 Dehydrin Ank_2 PF12796.7 KZN86102.1 - 2.1e-77 255.7 7.3 1e-12 48.5 0.0 12.6 8 4 4 12 12 12 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN86102.1 - 5e-58 192.8 15.7 1.2e-06 28.9 0.0 13.2 10 3 4 14 14 14 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN86102.1 - 8.7e-45 145.5 20.1 0.00051 20.3 0.1 20.2 22 0 0 22 22 21 9 Ankyrin repeat Ank PF00023.30 KZN86102.1 - 1.9e-39 132.4 33.4 1.5e-05 25.2 0.3 17.9 20 0 0 20 20 20 8 Ankyrin repeat Ank_5 PF13857.6 KZN86102.1 - 9e-37 124.7 20.7 0.0015 18.8 0.0 13.9 11 3 4 16 16 15 10 Ankyrin repeats (many copies) NACHT PF05729.12 KZN86102.1 - 6.5e-05 22.9 0.0 0.00021 21.2 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KZN86102.1 - 0.0002 21.8 0.0 0.0012 19.3 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Helo_like_N PF17111.5 KZN86102.1 - 0.00051 19.5 0.2 0.0012 18.3 0.2 1.6 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins NB-ARC PF00931.22 KZN86102.1 - 0.0082 15.4 0.0 0.018 14.2 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KZN86102.1 - 0.029 14.6 0.0 0.25 11.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KZN86102.1 - 0.04 14.3 0.0 0.38 11.2 0.0 2.6 3 0 0 3 3 3 0 RNA helicase Ribonuclease_3 PF00636.26 KZN86103.1 - 7.1e-08 33.0 0.0 2.9e-07 31.1 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KZN86103.1 - 6.9e-07 29.5 0.0 9.8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Pkinase PF00069.25 KZN86104.1 - 6e-17 61.9 0.0 2e-07 30.7 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KZN86104.1 - 3.9e-06 26.3 0.2 0.0001 21.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KZN86104.1 - 0.035 13.4 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_pol_B_thumb PF14791.6 KZN86104.1 - 0.044 14.0 0.1 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase beta thumb ABC_membrane PF00664.23 KZN86105.1 - 2.7e-39 135.5 10.6 3.8e-39 135.0 10.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KZN86105.1 - 8e-34 117.1 0.0 1.5e-33 116.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KZN86105.1 - 6.9e-06 25.6 0.1 0.0073 15.8 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KZN86105.1 - 0.00051 20.5 0.1 0.0013 19.1 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KZN86105.1 - 0.00073 19.8 0.0 0.0043 17.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KZN86105.1 - 0.0012 18.7 0.1 0.0071 16.2 0.0 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KZN86105.1 - 0.01 16.4 0.0 0.029 14.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KZN86105.1 - 0.01 15.6 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 KZN86105.1 - 0.011 15.8 0.0 0.29 11.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KZN86105.1 - 0.013 15.2 0.1 0.026 14.2 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain ATP-synt_ab PF00006.25 KZN86105.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.15 KZN86105.1 - 0.02 14.8 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 KZN86105.1 - 0.042 13.8 0.0 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 KZN86105.1 - 0.067 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 KZN86105.1 - 0.07 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KZN86105.1 - 0.072 13.5 0.0 0.38 11.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KZN86105.1 - 0.076 12.7 1.0 16 5.2 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein GPAT_N PF14829.6 KZN86105.1 - 0.087 12.8 0.0 4.1 7.5 0.0 3.2 4 0 0 4 4 3 0 Glycerol-3-phosphate acyltransferase N-terminal AAA_28 PF13521.6 KZN86105.1 - 0.096 12.9 0.0 0.36 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KZN86105.1 - 0.41 10.9 2.2 4.9 7.5 0.6 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AIM24 PF01987.17 KZN86106.1 - 3.1e-46 157.7 0.0 3.9e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DivIC PF04977.15 KZN86106.1 - 0.036 13.8 0.3 0.069 12.9 0.3 1.5 1 0 0 1 1 1 0 Septum formation initiator SLS PF14611.6 KZN86106.1 - 0.1 12.4 0.2 0.1 12.4 0.2 1.6 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator MFS_1 PF07690.16 KZN86107.1 - 6.4e-33 114.1 65.8 2.2e-25 89.4 39.6 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN86107.1 - 2.3e-07 30.1 33.3 0.00026 20.0 11.7 3.3 2 1 1 3 3 3 3 Sugar (and other) transporter Amidase PF01425.21 KZN86108.1 - 3.8e-68 230.5 0.0 3.9e-67 227.2 0.0 2.0 1 1 0 1 1 1 1 Amidase RAMA PF18755.1 KZN86108.1 - 0.009 16.4 1.1 0.018 15.4 1.1 1.4 1 0 0 1 1 1 1 Restriction Enzyme Adenine Methylase Associated Glyco_hydro_88 PF07470.13 KZN86109.1 - 7.2e-60 202.9 7.6 8.7e-60 202.6 7.6 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Pkinase PF00069.25 KZN86110.1 - 1.3e-15 57.5 0.0 2.2e-14 53.5 0.0 2.4 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN86110.1 - 4.3e-07 29.5 0.0 3.3e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KZN86110.1 - 0.0045 16.4 0.0 0.0069 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KZN86111.1 - 5e-13 49.5 0.0 8e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-AN1 PF01428.16 KZN86111.1 - 0.005 17.0 9.3 0.0093 16.1 9.3 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger DUF2180 PF09947.9 KZN86111.1 - 0.012 15.6 2.1 0.02 14.8 2.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) HCBP_related PF06594.11 KZN86111.1 - 0.11 12.5 0.2 21 5.2 0.1 2.4 2 0 0 2 2 2 0 Haemolysin-type calcium binding protein related domain Transp_Tc5_C PF04236.15 KZN86111.1 - 2.3 8.6 6.9 4.4 7.7 6.9 1.4 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain adh_short PF00106.25 KZN86112.1 - 8.5e-19 67.8 0.0 5.2e-18 65.2 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN86112.1 - 3e-13 49.9 0.0 4.7e-12 46.0 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN86112.1 - 0.0016 18.4 0.0 0.0024 17.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Kinesin PF00225.23 KZN86113.1 - 7.1e-81 271.7 5.4 2.1e-80 270.1 1.4 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KZN86113.1 - 2.6e-21 76.1 0.0 7.2e-21 74.7 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding HHH PF00633.23 KZN86113.1 - 0.00042 20.0 0.3 1.9 8.5 0.0 3.1 3 0 0 3 3 3 2 Helix-hairpin-helix motif HHH_5 PF14520.6 KZN86113.1 - 0.0015 19.1 0.0 2.8 8.6 0.0 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix domain Phage_cap_E PF03864.15 KZN86113.1 - 0.073 12.2 0.4 0.14 11.3 0.4 1.4 1 0 0 1 1 1 0 Phage major capsid protein E HHH_3 PF12836.7 KZN86113.1 - 0.094 13.0 0.1 18 5.7 0.0 3.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif MerR-DNA-bind PF09278.11 KZN86113.1 - 4.7 7.8 9.5 3 8.5 4.7 3.1 3 1 0 3 3 3 0 MerR, DNA binding DDHD PF02862.17 KZN86113.1 - 5.3 7.1 7.4 0.48 10.5 0.4 2.6 3 0 0 3 3 3 0 DDHD domain Sec23_trunk PF04811.15 KZN86114.1 - 4.2e-73 245.9 0.0 7.8e-73 245.0 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KZN86114.1 - 7.8e-24 83.5 0.4 4.7e-23 81.0 0.0 2.5 3 0 0 3 3 3 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KZN86114.1 - 8e-17 61.8 0.0 1.9e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KZN86114.1 - 1.4e-16 60.2 4.7 2.5e-16 59.4 4.7 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KZN86114.1 - 2e-10 40.4 0.0 3.9e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KZN86114.1 - 0.018 14.4 0.1 0.038 13.4 0.1 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Pkinase PF00069.25 KZN86115.1 - 1.7e-68 230.9 0.0 2e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN86115.1 - 3e-32 111.9 0.0 4e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KZN86115.1 - 0.00016 21.1 0.2 0.00025 20.5 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KZN86115.1 - 0.004 16.1 0.1 0.0063 15.5 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KZN86115.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KZN86115.1 - 0.031 14.2 0.3 0.094 12.6 0.3 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KZN86115.1 - 0.084 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 HEM4 PF02602.15 KZN86116.1 - 1.9e-40 138.6 0.0 2.3e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Aa_trans PF01490.18 KZN86117.1 - 5.5e-51 173.5 31.4 6.3e-51 173.4 31.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Fungal_trans_2 PF11951.8 KZN86118.1 - 1.1e-38 133.0 2.0 1.2e-38 132.9 2.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidohydro_3 PF07969.11 KZN86119.1 - 6.8e-70 236.8 0.0 7.8e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KZN86119.1 - 1.9e-15 57.0 0.0 2.4e-11 43.6 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family NmrA PF05368.13 KZN86120.1 - 2.3e-16 60.1 0.0 3e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KZN86120.1 - 2.9e-15 56.4 0.1 1.1e-14 54.5 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KZN86120.1 - 2.8e-14 53.4 0.0 4e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KZN86120.1 - 6.1e-11 41.8 0.1 1.1e-10 40.9 0.1 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KZN86120.1 - 2.8e-08 33.6 0.3 2.8e-07 30.2 0.1 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KZN86120.1 - 3.2e-08 33.0 0.0 5.7e-07 28.9 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KZN86120.1 - 5.7e-06 25.7 0.4 0.0057 15.9 0.0 2.7 1 1 2 3 3 3 2 Male sterility protein adh_short PF00106.25 KZN86120.1 - 5.2e-05 22.8 0.0 9.4e-05 22.0 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN86120.1 - 0.0024 17.5 0.0 0.0037 16.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SWI2_SNF2 PF18766.1 KZN86120.1 - 0.016 14.9 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase KR PF08659.10 KZN86120.1 - 0.045 13.7 0.0 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 KR domain DUF4838 PF16126.5 KZN86120.1 - 0.046 13.1 0.0 5.9 6.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4838) DDE_Tnp_1_3 PF13612.6 KZN86120.1 - 0.097 12.7 0.0 0.29 11.1 0.0 1.7 2 0 0 2 2 2 0 Transposase DDE domain HIT PF01230.23 KZN86121.1 - 6.2e-17 62.1 0.0 1e-16 61.5 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KZN86121.1 - 5.7e-09 36.5 0.0 6.9e-09 36.2 0.0 1.3 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KZN86121.1 - 0.016 15.1 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 CRAL_TRIO PF00650.20 KZN86122.1 - 1.6e-42 145.0 0.0 2.8e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KZN86122.1 - 1.5e-14 53.9 1.7 4.1e-14 52.5 0.4 2.4 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KZN86122.1 - 3.3e-06 27.3 0.0 5.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Skp1 PF01466.19 KZN86122.1 - 0.18 12.0 1.3 3.6 7.8 0.1 2.8 3 0 0 3 3 3 0 Skp1 family, dimerisation domain DASH_Dam1 PF08653.10 KZN86123.1 - 2.3e-29 101.0 2.3 3e-29 100.6 2.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 UCH PF00443.29 KZN86124.1 - 4.8e-46 157.3 0.8 6.2e-46 157.0 0.8 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KZN86124.1 - 8.9e-16 58.4 4.1 6.9e-15 55.4 4.1 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KZN86124.1 - 0.0034 17.7 1.4 0.0034 17.7 1.4 3.3 3 1 1 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_C98 PF15499.6 KZN86124.1 - 2.8 7.3 10.3 0.47 9.9 0.1 3.4 4 1 0 4 4 4 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Ribosomal_S14 PF00253.21 KZN86125.1 - 6.3e-15 54.7 5.1 6.8e-15 54.6 5.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Ytp1 PF10355.9 KZN86126.1 - 9.6e-117 389.1 8.7 1.6e-116 388.4 8.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KZN86126.1 - 2.9e-31 107.3 12.9 1.7e-29 101.7 5.3 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF2427) DLH PF01738.18 KZN86127.1 - 1.4e-31 109.7 0.0 1.6e-31 109.5 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KZN86127.1 - 0.035 13.7 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Rhomboid PF01694.22 KZN86128.1 - 1.4e-16 60.8 9.3 1.4e-16 60.8 9.3 1.5 2 0 0 2 2 2 1 Rhomboid family Gaa1 PF04114.14 KZN86129.1 - 7.4e-188 625.6 4.5 9.3e-188 625.3 4.5 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component LysM PF01476.20 KZN86130.1 - 0.011 15.7 0.3 0.021 14.8 0.1 1.6 2 0 0 2 2 2 0 LysM domain Chitin_bind_1 PF00187.19 KZN86130.1 - 0.2 12.2 13.9 0.17 12.4 9.6 3.1 2 1 0 2 2 2 0 Chitin recognition protein NPR3 PF03666.13 KZN86130.1 - 1.2 7.9 3.3 15 4.2 0.0 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 PCI PF01399.27 KZN86131.1 - 3.3e-10 40.4 0.0 6.4e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 KZN86131.1 - 0.00011 21.7 0.7 0.00023 20.7 0.7 1.5 1 0 0 1 1 1 1 Rpn9 C-terminal helix DUF3990 PF13151.6 KZN86131.1 - 0.07 12.8 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3990) Dimerisation2 PF16864.5 KZN86131.1 - 0.14 12.1 1.3 0.47 10.5 0.0 2.5 3 0 0 3 3 3 0 Dimerisation domain RicinB_lectin_2 PF14200.6 KZN86132.1 - 7.8e-20 71.4 3.5 3.2e-11 43.8 0.2 2.5 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KZN86132.1 - 3.5e-05 24.0 0.0 4.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Ribosomal_L31e PF01198.19 KZN86133.1 - 3.4e-40 136.2 0.9 4.6e-40 135.7 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e MS_channel PF00924.18 KZN86133.1 - 0.0066 16.0 0.0 0.0083 15.7 0.0 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel TrbC_Ftype PF09673.10 KZN86133.1 - 0.12 12.4 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein CN_hydrolase PF00795.22 KZN86134.1 - 4.7e-57 193.3 0.0 5.3e-57 193.1 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase APH PF01636.23 KZN86135.1 - 1.6e-10 41.3 0.0 1.9e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1664 PF07889.12 KZN86136.1 - 0.047 13.7 0.0 0.063 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF5137 PF17220.3 KZN86136.1 - 0.085 13.7 0.1 0.15 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF5137) COG2 PF06148.11 KZN86136.1 - 0.089 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 CDC50 PF03381.15 KZN86139.1 - 2e-67 227.7 1.1 2.6e-67 227.3 1.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family MGC-24 PF05283.11 KZN86141.1 - 3.9 7.9 20.2 9.4 6.7 4.5 2.1 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FAM117 PF15388.6 KZN86141.1 - 8.3 5.7 12.5 11 5.3 12.5 1.1 1 0 0 1 1 1 0 Protein Family FAM117 Ran_BP1 PF00638.18 KZN86142.1 - 1.2e-10 41.7 0.0 2.3e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.11 KZN86142.1 - 5.6e-06 26.9 1.7 5.6e-06 26.9 1.7 7.9 8 2 0 8 8 8 1 NUP50 (Nucleoporin 50 kDa) Pectate_lyase_3 PF12708.7 KZN86143.1 - 6.1e-96 320.4 24.1 1.6e-83 279.8 9.9 3.2 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KZN86143.1 - 3.8e-08 32.9 2.9 0.0025 17.5 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Cyclase PF04199.13 KZN86144.1 - 8e-16 58.5 0.0 1.1e-15 58.1 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase adh_short_C2 PF13561.6 KZN86145.1 - 3.2e-60 203.6 0.3 3.6e-60 203.4 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN86145.1 - 4.5e-41 140.5 0.3 5.4e-41 140.2 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN86145.1 - 2.2e-12 47.3 0.1 3.6e-12 46.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Mrr_cat PF04471.12 KZN86145.1 - 0.011 15.7 0.1 0.025 14.6 0.1 1.7 1 1 0 1 1 1 0 Restriction endonuclease Chorion_S16 PF05836.12 KZN86145.1 - 0.094 13.0 1.0 0.24 11.6 0.4 1.9 1 1 1 2 2 2 0 Chorion protein S16 YjeF_N PF03853.15 KZN86145.1 - 0.1 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus adh_short_C2 PF13561.6 KZN86146.1 - 3e-53 180.8 0.0 3.7e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN86146.1 - 3.1e-41 141.0 0.0 4.3e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN86146.1 - 1.1e-13 51.5 0.0 1.5e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KZN86146.1 - 0.00091 18.7 0.0 0.28 10.5 0.0 2.0 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KZN86146.1 - 0.0036 16.8 0.0 0.025 14.0 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glu_dehyd_C PF16912.5 KZN86146.1 - 0.015 14.7 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus 3Beta_HSD PF01073.19 KZN86146.1 - 0.055 12.5 0.0 0.082 11.9 0.0 1.3 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ThiF PF00899.21 KZN86146.1 - 0.086 12.2 0.5 4.2 6.6 0.1 2.6 2 1 0 2 2 2 0 ThiF family Shikimate_DH PF01488.20 KZN86146.1 - 0.1 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_transf_5 PF08323.11 KZN86146.1 - 0.17 11.5 0.0 0.39 10.4 0.0 1.5 2 0 0 2 2 2 0 Starch synthase catalytic domain ABC_tran PF00005.27 KZN86148.1 - 2.5e-43 147.9 0.0 2e-25 89.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KZN86148.1 - 8.4e-34 117.5 20.7 2.8e-21 76.4 8.8 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KZN86148.1 - 1.7e-12 47.3 4.6 1.5e-05 24.5 0.2 4.2 2 2 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KZN86148.1 - 2.9e-08 33.9 0.3 0.13 12.0 0.0 4.3 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KZN86148.1 - 5.5e-06 26.7 0.6 0.18 12.1 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KZN86148.1 - 7.5e-06 25.6 2.0 0.014 15.1 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KZN86148.1 - 2.3e-05 24.9 0.7 0.096 13.1 0.1 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 KZN86148.1 - 0.0002 21.9 2.2 0.07 13.6 0.3 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KZN86148.1 - 0.00046 19.8 0.6 0.04 13.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KZN86148.1 - 0.00058 19.8 1.3 1.3 8.9 0.0 3.1 3 0 0 3 3 3 2 NACHT domain RsgA_GTPase PF03193.16 KZN86148.1 - 0.00099 19.1 0.3 1.4 8.8 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase T2SSE PF00437.20 KZN86148.1 - 0.002 17.2 1.9 1 8.4 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.23 KZN86148.1 - 0.0043 17.1 0.4 1.3 9.1 0.0 3.1 3 0 0 3 3 2 1 50S ribosome-binding GTPase cobW PF02492.19 KZN86148.1 - 0.0051 16.4 1.2 0.13 11.8 0.1 2.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 KZN86148.1 - 0.0068 16.5 1.8 0.021 14.9 0.2 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_30 PF13604.6 KZN86148.1 - 0.0078 16.0 0.0 3.9 7.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KZN86148.1 - 0.018 14.8 0.0 6.3 6.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 KZN86148.1 - 0.021 15.0 0.6 4.9 7.3 0.1 3.0 2 1 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 KZN86148.1 - 0.032 13.7 1.0 6.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein ATP_bind_1 PF03029.17 KZN86148.1 - 0.034 13.9 0.1 16 5.2 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 KZN86148.1 - 0.042 13.9 0.0 0.66 10.0 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FtsK_SpoIIIE PF01580.18 KZN86148.1 - 0.049 13.0 2.8 0.92 8.8 0.4 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 KZN86148.1 - 0.078 12.3 0.2 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 KZN86148.1 - 0.088 12.3 0.2 17 4.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 KZN86148.1 - 0.09 12.7 0.7 7.6 6.4 0.1 2.5 2 0 0 2 2 2 0 NTPase TrwB_AAD_bind PF10412.9 KZN86148.1 - 0.14 11.1 1.4 2.6 6.9 0.2 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.6 KZN86148.1 - 0.16 12.5 0.0 29 5.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 KZN86148.1 - 0.16 10.7 0.2 1.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Predicted ATPase of the ABC class m04gp34like PF12216.8 KZN86148.1 - 0.17 11.4 0.0 0.42 10.2 0.0 1.6 1 0 0 1 1 1 0 Immune evasion protein DUF2075 PF09848.9 KZN86148.1 - 0.21 10.8 1.0 4.2 6.5 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 KZN86148.1 - 0.3 10.4 1.1 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 KaiC IstB_IS21 PF01695.17 KZN86148.1 - 0.58 9.9 2.5 30 4.3 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein Dynamin_N PF00350.23 KZN86148.1 - 1.3 9.1 6.4 4 7.5 0.1 2.8 3 0 0 3 3 2 0 Dynamin family SCP2 PF02036.17 KZN86149.1 - 4.6e-26 91.3 0.7 7.2e-26 90.6 0.7 1.3 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KZN86149.1 - 1.2e-06 28.8 0.1 1.6e-06 28.4 0.1 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 KZN86149.1 - 0.01 16.2 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 0 Sterol carrier protein domain YebF PF13995.6 KZN86149.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 YebF-like protein F-box PF00646.33 KZN86150.1 - 0.023 14.6 0.5 0.075 12.9 0.5 1.8 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KZN86150.1 - 0.031 14.1 0.1 0.096 12.6 0.1 1.8 1 0 0 1 1 1 0 F-box-like SNF2_N PF00176.23 KZN86151.1 - 1.4e-65 221.3 0.2 2.3e-65 220.6 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KZN86151.1 - 2.8e-16 59.9 0.0 6.2e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 KZN86151.1 - 2e-07 30.7 2.9 4.7e-07 29.6 2.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KZN86151.1 - 1e-06 28.5 4.5 2.5e-06 27.2 4.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KZN86151.1 - 3.2e-06 27.2 0.0 9e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.6 KZN86151.1 - 7.5e-05 22.7 2.1 0.00016 21.6 2.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KZN86151.1 - 0.00025 20.8 5.3 0.00049 19.9 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KZN86151.1 - 0.00033 20.7 1.7 0.00074 19.6 1.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KZN86151.1 - 0.00052 20.3 4.8 0.0013 19.0 4.8 1.7 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KZN86151.1 - 0.056 13.3 6.5 0.46 10.4 7.2 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KZN86151.1 - 0.14 12.0 5.9 0.57 10.0 5.2 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 KZN86151.1 - 0.3 11.1 6.0 1.3 9.0 6.4 1.9 1 1 0 1 1 1 0 zinc-RING finger domain Ras PF00071.22 KZN86152.1 - 4.2e-49 166.2 0.0 5.1e-49 166.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KZN86152.1 - 3e-29 101.7 0.1 7.6e-29 100.4 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KZN86152.1 - 1.3e-10 41.0 0.0 1.7e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 KZN86152.1 - 0.00062 20.1 0.1 0.005 17.2 0.1 2.1 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 KZN86152.1 - 0.00067 19.7 0.0 0.0015 18.6 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KZN86152.1 - 0.0015 17.9 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 KZN86152.1 - 0.015 15.0 0.1 0.021 14.6 0.1 1.4 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 KZN86152.1 - 0.015 14.4 1.9 1.4 8.0 0.1 2.8 2 1 1 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.12 KZN86152.1 - 0.017 14.6 0.1 0.031 13.8 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 KZN86152.1 - 0.029 13.9 0.1 0.046 13.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KZN86152.1 - 0.075 13.4 0.1 0.13 12.6 0.0 1.5 2 0 0 2 2 1 0 AAA ATPase domain ArgoMid PF16487.5 KZN86152.1 - 0.083 13.2 0.1 0.2 11.9 0.0 1.7 2 0 0 2 2 2 0 Mid domain of argonaute RsgA_GTPase PF03193.16 KZN86152.1 - 0.09 12.7 0.1 8.9 6.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 KZN86152.1 - 0.098 12.7 0.1 0.23 11.5 0.2 1.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRPRB PF09439.10 KZN86152.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.18 KZN86152.1 - 0.12 11.6 0.4 0.21 10.8 0.0 1.6 2 0 0 2 2 2 0 Septin AAA_33 PF13671.6 KZN86152.1 - 0.22 11.7 0.2 0.22 11.7 0.2 1.6 2 0 0 2 2 2 0 AAA domain Nas2_N PF18265.1 KZN86153.1 - 2.7e-29 100.9 0.1 3.9e-29 100.4 0.1 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 KZN86153.1 - 6.7e-12 45.1 0.1 1.1e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KZN86153.1 - 3.1e-09 37.0 0.0 6.3e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KZN86153.1 - 4.2e-06 27.0 0.0 7.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KZN86153.1 - 8.2e-06 26.2 0.0 1.4e-05 25.4 0.0 1.5 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain RhoGEF PF00621.20 KZN86154.1 - 3.3e-22 79.6 0.0 6.5e-22 78.6 0.0 1.5 1 1 0 1 1 1 1 RhoGEF domain PH_10 PF15411.6 KZN86154.1 - 0.13 12.6 0.3 1.4 9.2 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain SBDS PF01172.18 KZN86155.1 - 4e-24 84.5 0.0 5.1e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein UDG PF03167.19 KZN86156.1 - 4.2e-19 69.1 0.0 7.5e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily 7TMR-DISM_7TM PF07695.11 KZN86157.1 - 0.22 11.4 3.7 0.28 11.1 3.7 1.2 1 0 0 1 1 1 0 7TM diverse intracellular signalling NAD_binding_6 PF08030.12 KZN86158.1 - 4.3e-21 75.7 0.0 7.6e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KZN86158.1 - 3.4e-20 72.4 9.5 3.4e-20 72.4 9.5 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KZN86158.1 - 4.4e-20 71.8 0.0 9.4e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.24 KZN86158.1 - 0.0096 16.3 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Phage_holin_4_1 PF05105.12 KZN86159.1 - 0.22 11.7 5.9 0.089 12.9 2.6 2.0 1 1 1 2 2 2 0 Bacteriophage holin family 4HB_MCP_1 PF12729.7 KZN86159.1 - 0.23 11.0 0.3 0.36 10.4 0.3 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Methyltransf_2 PF00891.18 KZN86160.1 - 3.8e-19 68.8 0.0 5.4e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 KZN86160.1 - 0.00023 21.1 0.1 0.00057 19.9 0.1 1.7 1 0 0 1 1 1 1 Dimerisation domain NinB PF05772.12 KZN86160.1 - 0.17 11.7 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 NinB protein Bac_luciferase PF00296.20 KZN86161.1 - 3e-60 204.3 0.3 3.8e-60 204.0 0.3 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase NRDE-2 PF08424.10 KZN86162.1 - 1.9e-83 280.2 0.1 1.1e-82 277.8 0.0 2.0 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference BP28CT PF08146.12 KZN86163.1 - 1.2e-42 145.4 1.5 1.1e-41 142.3 0.9 2.5 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 KZN86163.1 - 8.1e-27 93.9 0.7 1.5e-25 89.8 0.4 3.5 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 KZN86163.1 - 5.2e-09 36.4 0.7 0.22 11.9 0.0 6.8 7 0 0 7 7 7 3 HEAT repeats HEAT PF02985.22 KZN86163.1 - 4.5e-05 23.4 0.9 1.7 9.1 0.0 6.3 6 0 0 6 6 6 1 HEAT repeat CARD PF00619.21 KZN86163.1 - 0.009 16.0 2.2 0.023 14.7 0.1 2.8 3 0 0 3 3 3 1 Caspase recruitment domain HEAT_EZ PF13513.6 KZN86163.1 - 0.042 14.4 14.2 4.3 7.9 0.1 7.8 7 2 2 9 9 9 0 HEAT-like repeat DUF5525 PF17663.1 KZN86163.1 - 0.13 10.4 0.0 0.19 9.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5525) SSF PF00474.17 KZN86164.1 - 8e-23 81.0 30.5 8e-23 81.0 30.5 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family Glyco_hydro_18 PF00704.28 KZN86165.1 - 4.2e-84 282.9 4.1 4.9e-84 282.7 4.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 AP_endonuc_2 PF01261.24 KZN86165.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel EthD PF07110.11 KZN86166.1 - 7.5e-20 71.9 1.7 8.9e-20 71.7 1.7 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KZN86166.1 - 0.00025 21.5 0.0 0.00053 20.4 0.0 1.5 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase Arrestin_N PF00339.29 KZN86167.1 - 9.4e-06 25.7 0.0 4.4e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 KZN86167.1 - 9.7e-05 21.9 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 Bul1 C terminus Bul1_N PF04425.12 KZN86167.1 - 0.0004 19.3 1.9 0.0027 16.6 0.4 2.5 1 1 1 2 2 2 1 Bul1 N terminus MMS1_N PF10433.9 KZN86168.1 - 1.2e-153 512.3 0.0 1.7e-153 511.8 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KZN86168.1 - 3.7e-100 335.4 0.0 3.9e-99 332.0 0.0 2.3 2 0 0 2 2 2 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 KZN86168.1 - 0.029 14.7 0.0 0.68 10.3 0.0 3.1 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain ubiquitin PF00240.23 KZN86169.1 - 1.7e-19 69.3 0.0 2.5e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KZN86169.1 - 2.1e-07 30.7 0.2 2.1e-07 30.7 0.2 2.1 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.8 KZN86169.1 - 3e-07 30.2 0.0 5.1e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KZN86169.1 - 6.2e-05 23.5 0.1 0.00013 22.5 0.1 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KZN86169.1 - 7.7e-05 22.8 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 KZN86169.1 - 0.0023 18.6 0.0 0.0051 17.5 0.0 1.6 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD GerD PF17898.1 KZN86169.1 - 0.069 13.1 4.2 0.18 11.8 4.1 1.8 1 1 0 1 1 1 0 Spore germination GerD central core domain Ubiquitin_2 PF14560.6 KZN86169.1 - 0.18 12.3 0.1 0.5 10.8 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain HOIP-UBA PF16678.5 KZN86169.1 - 0.23 11.5 0.0 0.48 10.4 0.0 1.5 1 0 0 1 1 1 0 HOIP UBA domain pair DUF2477 PF10631.9 KZN86169.1 - 1.3 9.6 8.6 0.085 13.5 0.6 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2477) STI1 PF17830.1 KZN86169.1 - 1.6 8.7 21.7 1.2 9.1 2.7 3.5 2 1 1 3 3 3 0 STI1 domain XPC-binding PF09280.11 KZN86169.1 - 6.6 6.5 13.4 20 5.0 5.6 3.6 2 1 1 3 3 3 0 XPC-binding domain EMP70 PF02990.16 KZN86170.1 - 4.7e-200 665.7 0.1 6.3e-200 665.3 0.1 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Sulfatase PF00884.23 KZN86171.1 - 2.7e-59 201.1 0.2 3.9e-59 200.6 0.2 1.2 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 KZN86171.1 - 2.1e-22 78.6 0.6 4.4e-22 77.6 0.6 1.6 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 KZN86171.1 - 4.2e-08 33.2 0.1 2.9e-06 27.1 0.1 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 KZN86171.1 - 0.0019 18.9 0.3 0.024 15.4 0.3 2.3 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.17 KZN86171.1 - 0.0026 16.5 0.0 0.0033 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4976 PF16347.5 KZN86171.1 - 0.005 17.1 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) DUF1501 PF07394.12 KZN86171.1 - 0.0064 15.6 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) Metalloenzyme PF01676.18 KZN86171.1 - 0.065 12.6 0.0 0.22 10.9 0.0 1.8 2 0 0 2 2 2 0 Metalloenzyme superfamily CN_hydrolase PF00795.22 KZN86172.1 - 7.1e-31 107.5 0.0 4.3e-30 104.9 0.0 2.1 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase LRRC37 PF15779.5 KZN86172.1 - 0.009 16.3 2.7 0.02 15.2 2.7 1.5 1 0 0 1 1 1 1 Leucine-rich repeat-containing protein 37 family Lactamase_B_2 PF12706.7 KZN86174.1 - 2.2e-11 43.6 1.6 1.4e-07 31.3 0.0 2.8 2 1 1 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KZN86174.1 - 2.2e-10 40.7 0.1 5e-10 39.5 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Pyridoxal_deC PF00282.19 KZN86175.1 - 6.2e-79 265.4 0.0 1e-78 264.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain AMP-binding PF00501.28 KZN86176.1 - 6.6e-39 133.7 0.0 9e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KZN86176.1 - 3.9e-07 29.9 0.6 3.9e-07 29.9 0.6 1.8 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus PALP PF00291.25 KZN86179.1 - 6.1e-41 140.7 2.0 9e-41 140.2 2.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SBDS_C PF09377.10 KZN86180.1 - 1.4e-42 144.4 0.0 2.2e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 KZN86180.1 - 2.4e-31 107.6 0.0 4.6e-31 106.7 0.0 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Peptidase_S10 PF00450.22 KZN86181.1 - 9.1e-127 423.9 0.4 1.1e-126 423.7 0.4 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 KZN86181.1 - 9.5e-14 52.0 0.0 2.2e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Ribosomal_S13 PF00416.22 KZN86182.1 - 1.4e-56 190.4 3.0 1.7e-56 190.1 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF1822 PF08852.11 KZN86182.1 - 0.0062 15.6 0.0 0.008 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1822) FbpA PF05833.11 KZN86182.1 - 0.016 14.0 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 KZN86182.1 - 0.034 14.4 0.1 0.11 12.8 0.1 1.8 1 1 0 1 1 1 0 Helix-hairpin-helix motif DUF2746 PF10874.8 KZN86182.1 - 0.081 13.4 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) peroxidase PF00141.23 KZN86184.1 - 7.3e-44 150.2 0.0 1.1e-43 149.6 0.0 1.3 1 0 0 1 1 1 1 Peroxidase DUF4003 PF13170.6 KZN86184.1 - 0.072 12.4 0.0 0.16 11.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4003) Lebercilin PF15619.6 KZN86185.1 - 0.015 14.9 5.6 0.027 14.1 5.6 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 KZN86185.1 - 0.021 13.7 2.0 0.03 13.2 2.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TEX13 PF15186.6 KZN86185.1 - 0.13 12.0 5.0 0.21 11.3 5.0 1.3 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family SKA2 PF16740.5 KZN86185.1 - 0.17 11.6 3.3 0.32 10.8 1.0 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 TMF_TATA_bd PF12325.8 KZN86185.1 - 1.1 9.5 9.3 1.2 9.4 1.2 2.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.8 KZN86185.1 - 1.6 8.8 8.5 1 9.4 4.9 2.2 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Iso_dh PF00180.20 KZN86186.1 - 1.9e-107 359.4 0.0 2.2e-107 359.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase TPR_2 PF07719.17 KZN86187.1 - 2.2e-07 30.4 1.7 0.032 14.3 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KZN86187.1 - 0.00012 21.7 3.8 1.8 8.6 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KZN86187.1 - 0.014 15.6 1.1 0.027 14.7 1.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Pox_T4_N PF04491.12 KZN86187.1 - 0.038 13.9 0.0 0.099 12.5 0.0 1.6 1 0 0 1 1 1 0 Poxvirus T4 protein, N terminus TPR_8 PF13181.6 KZN86187.1 - 0.32 11.3 1.5 12 6.4 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_10 PF00331.20 KZN86188.1 - 2e-70 237.5 0.1 2.3e-70 237.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 KZN86188.1 - 1.1e-11 44.5 12.0 1.1e-11 44.5 12.0 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain Ribonuclease PF00545.20 KZN86188.1 - 0.0082 16.9 0.0 0.021 15.5 0.0 1.7 1 0 0 1 1 1 1 ribonuclease DUF2841 PF11001.8 KZN86189.1 - 8.2e-43 145.4 0.6 8.2e-43 145.4 0.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) SSXT PF05030.12 KZN86190.1 - 1.4e-07 31.0 0.0 0.023 14.3 0.0 2.4 2 0 0 2 2 2 2 SSXT protein (N-terminal region) DUF108 PF01958.18 KZN86190.1 - 0.15 12.4 2.2 0.33 11.4 2.2 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF108 TFIIA PF03153.13 KZN86190.1 - 5.6 6.9 22.3 6.8 6.6 22.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PDZ_1 PF12812.7 KZN86191.1 - 5.3e-52 173.7 0.0 4.5e-34 116.3 0.0 2.7 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 KZN86191.1 - 1.9e-23 84.0 1.3 4.3e-21 76.4 0.1 2.6 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 KZN86191.1 - 3.9e-16 58.6 0.4 6.7e-08 32.3 0.2 4.5 4 0 0 4 4 4 3 PDZ domain PDZ_2 PF13180.6 KZN86191.1 - 9.2e-10 38.7 0.1 0.00038 20.7 0.0 4.4 4 0 0 4 4 4 2 PDZ domain PDZ PF00595.24 KZN86191.1 - 1.7e-05 25.1 0.0 0.02 15.3 0.0 3.6 3 0 0 3 3 3 1 PDZ domain Tricorn_PDZ PF14685.6 KZN86191.1 - 0.014 15.4 0.5 1.8 8.6 0.1 3.3 3 0 0 3 3 3 0 Tricorn protease PDZ domain 4HPAD_g_N PF18671.1 KZN86191.1 - 0.023 14.4 0.6 0.12 12.1 0.0 2.5 2 0 0 2 2 2 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Peptidase_S46 PF10459.9 KZN86191.1 - 0.24 10.0 0.0 0.43 9.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase S46 INCENP_ARK-bind PF03941.15 KZN86192.1 - 4.8e-16 58.4 2.1 1.9e-15 56.5 2.1 2.2 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region ERM PF00769.19 KZN86192.1 - 0.0038 17.1 29.0 0.0038 17.1 29.0 4.2 4 0 0 4 4 4 2 Ezrin/radixin/moesin family PP-binding PF00550.25 KZN86193.1 - 1.9e-07 31.3 0.1 4.3e-07 30.2 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Reticulon PF02453.17 KZN86194.1 - 2.1e-26 92.7 4.4 2.8e-26 92.3 4.4 1.2 1 0 0 1 1 1 1 Reticulon DUF3150 PF11348.8 KZN86194.1 - 0.064 12.5 0.1 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3150) BRX_N PF13713.6 KZN86194.1 - 0.1 12.4 0.0 0.33 10.8 0.0 1.8 2 0 0 2 2 2 0 Transcription factor BRX N-terminal domain DNA_topoisoIV PF00521.20 KZN86196.1 - 1.8e-135 452.1 0.0 3.1e-135 451.4 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KZN86196.1 - 7.4e-52 175.0 4.2 5.6e-51 172.1 2.4 2.7 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KZN86196.1 - 2.5e-24 85.7 0.2 6e-24 84.5 0.2 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KZN86196.1 - 5.3e-16 59.1 0.1 1.7e-15 57.5 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KZN86196.1 - 1.7e-06 28.2 0.0 6.3e-06 26.3 0.0 2.0 1 0 0 1 1 1 1 Toprim domain RabGAP-TBC PF00566.18 KZN86197.1 - 6.4e-49 166.5 0.1 3.9e-48 163.9 0.0 2.4 2 1 1 3 3 3 1 Rab-GTPase-TBC domain DUF1512 PF07431.12 KZN86197.1 - 0.23 10.4 1.6 0.45 9.4 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) YabA PF06156.13 KZN86197.1 - 0.26 12.0 0.1 0.26 12.0 0.1 3.3 4 0 0 4 4 4 0 Initiation control protein YabA IFP_35_N PF07334.13 KZN86197.1 - 2.8 8.1 7.6 0.2 11.8 0.3 2.7 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Phage_GP20 PF06810.11 KZN86197.1 - 3.8 7.3 9.1 1.5 8.7 0.0 3.0 3 0 0 3 3 3 0 Phage minor structural protein GP20 Occludin_ELL PF07303.13 KZN86197.1 - 7.2 7.4 12.9 13 6.6 1.1 4.2 4 1 0 4 4 4 0 Occludin homology domain DUF3405 PF11885.8 KZN86198.1 - 3e-159 530.9 2.6 3.5e-159 530.7 2.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) adh_short_C2 PF13561.6 KZN86200.1 - 2.4e-56 190.9 6.2 2.8e-56 190.7 6.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN86200.1 - 1.2e-45 155.4 6.4 1.5e-45 155.0 6.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN86200.1 - 3e-11 43.5 5.7 4.7e-11 42.9 5.7 1.2 1 0 0 1 1 1 1 KR domain YAcAr PF10686.9 KZN86200.1 - 0.0015 18.4 1.0 0.0081 16.1 0.9 2.2 1 1 1 2 2 2 1 YspA, cpYpsA-related SLOG family Mur_ligase PF01225.25 KZN86200.1 - 0.024 15.0 1.2 0.072 13.4 0.9 1.9 2 0 0 2 2 2 0 Mur ligase family, catalytic domain ACT PF01842.25 KZN86200.1 - 0.19 11.5 0.6 0.4 10.5 0.2 1.7 2 0 0 2 2 2 0 ACT domain Glyco_hydro_92 PF07971.12 KZN86201.1 - 2.5e-150 501.4 0.3 3e-150 501.2 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KZN86201.1 - 3.1e-51 174.6 0.0 5.8e-51 173.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Zn_clus PF00172.18 KZN86202.1 - 2.5e-08 33.9 12.1 3.9e-08 33.3 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KZN86202.1 - 0.018 13.8 0.1 0.063 12.1 0.1 1.9 1 1 0 1 1 1 0 Fungal specific transcription factor domain MFS_1 PF07690.16 KZN86203.1 - 2.3e-24 86.0 35.8 2.3e-24 86.0 35.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RNA_POL_M_15KD PF02150.16 KZN86204.1 - 0.0014 18.5 5.7 0.024 14.5 1.3 2.5 2 0 0 2 2 2 2 RNA polymerases M/15 Kd subunit DZR PF12773.7 KZN86204.1 - 0.092 12.8 1.4 0.21 11.6 1.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon Med4 PF10018.9 KZN86205.1 - 1.5e-50 171.6 0.2 2.5e-50 170.9 0.2 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 HsbA PF12296.8 KZN86205.1 - 0.017 15.5 0.9 0.059 13.8 0.9 1.9 1 1 0 1 1 1 0 Hydrophobic surface binding protein A Baculo_PEP_C PF04513.12 KZN86205.1 - 0.075 13.1 0.4 0.15 12.1 0.4 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus LPP PF04728.13 KZN86205.1 - 0.097 13.1 0.3 2.2 8.7 0.0 2.8 2 0 0 2 2 2 0 Lipoprotein leucine-zipper YL1 PF05764.13 KZN86205.1 - 0.19 11.9 2.7 0.15 12.1 0.4 1.9 2 0 0 2 2 2 0 YL1 nuclear protein SnoaL PF07366.12 KZN86206.1 - 6.9e-05 22.7 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KZN86206.1 - 0.00029 21.4 0.1 0.00057 20.5 0.1 1.5 1 0 0 1 1 1 1 SnoaL-like domain COesterase PF00135.28 KZN86207.1 - 5.3e-73 246.6 0.0 7.2e-73 246.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KZN86207.1 - 1.1e-07 31.9 0.2 7.4e-07 29.2 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KZN86207.1 - 0.014 14.3 0.0 0.31 9.9 0.0 2.0 2 0 0 2 2 2 0 Steryl acetyl hydrolase Beta-lactamase PF00144.24 KZN86209.1 - 5.8e-49 167.1 0.3 7.8e-49 166.7 0.3 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KZN86209.1 - 2.9e-18 66.2 0.0 5.7e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) CFEM PF05730.11 KZN86210.1 - 2.4e-11 43.6 11.0 3.9e-11 42.9 11.0 1.4 1 0 0 1 1 1 1 CFEM domain Mito_carr PF00153.27 KZN86211.1 - 3e-59 197.0 5.1 1.7e-19 69.5 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.13 KZN86211.1 - 5.2 7.2 5.7 0.73 10.0 0.2 2.3 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif UQ_con PF00179.26 KZN86213.1 - 6.7e-44 148.9 0.0 7.6e-44 148.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KZN86213.1 - 0.085 13.1 1.0 0.11 12.7 1.0 1.4 1 1 0 1 1 1 0 RWD domain RTA1 PF04479.13 KZN86214.1 - 8.5e-72 241.1 6.0 1.1e-71 240.7 6.0 1.1 1 0 0 1 1 1 1 RTA1 like protein DctQ PF04290.12 KZN86214.1 - 0.013 15.5 0.8 0.013 15.5 0.8 2.6 2 1 1 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component PhrC_PhrF PF11131.8 KZN86214.1 - 0.1 12.2 0.4 0.1 12.2 0.4 2.3 3 0 0 3 3 3 0 Rap-phr extracellular signalling Zn_clus PF00172.18 KZN86215.1 - 6.6e-10 39.0 10.0 1.1e-09 38.2 10.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KZN86215.1 - 0.0012 17.7 0.4 0.0017 17.3 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC_membrane PF00664.23 KZN86216.1 - 4.5e-92 308.6 26.4 1.3e-47 162.7 15.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KZN86216.1 - 2.4e-69 232.1 0.0 1.4e-34 119.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KZN86216.1 - 9.3e-18 64.5 1.0 3.3e-05 23.4 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KZN86216.1 - 3.4e-12 45.9 1.6 0.0019 17.1 0.1 4.4 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 KZN86216.1 - 4e-10 40.4 0.9 0.00021 21.7 0.1 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KZN86216.1 - 1.2e-09 38.4 0.0 0.015 15.1 0.0 4.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KZN86216.1 - 4e-09 36.1 0.5 0.00033 20.3 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KZN86216.1 - 7.9e-09 36.3 0.1 0.00056 20.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KZN86216.1 - 4.3e-08 33.5 0.0 0.023 15.0 0.0 3.4 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KZN86216.1 - 1.8e-07 31.2 0.0 0.016 15.1 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 KZN86216.1 - 4e-07 30.1 0.0 0.0026 17.5 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KZN86216.1 - 9e-06 26.1 0.0 0.043 14.2 0.0 4.5 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KZN86216.1 - 1.6e-05 25.5 0.0 0.16 12.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 KZN86216.1 - 1.7e-05 24.8 0.0 0.032 14.2 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_5 PF07728.14 KZN86216.1 - 2.3e-05 24.4 0.2 0.64 10.0 0.0 3.8 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KZN86216.1 - 9.2e-05 22.2 0.3 0.73 9.5 0.0 3.3 3 1 0 3 3 3 2 AAA domain AAA_33 PF13671.6 KZN86216.1 - 0.00014 22.1 0.0 0.35 11.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 KZN86216.1 - 0.00025 20.6 0.0 0.27 10.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 KZN86216.1 - 0.00038 20.1 0.1 0.34 10.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 KZN86216.1 - 0.00052 19.3 0.0 3.6 6.7 0.0 3.2 3 0 0 3 3 3 1 NB-ARC domain AAA_28 PF13521.6 KZN86216.1 - 0.00087 19.6 0.1 1.1 9.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KZN86216.1 - 0.0019 18.0 0.1 2.3 7.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KZN86216.1 - 0.002 17.5 0.1 1.9 7.7 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin DUF87 PF01935.17 KZN86216.1 - 0.0039 17.3 0.1 1.7 8.7 0.0 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain G-alpha PF00503.20 KZN86216.1 - 0.005 16.0 0.0 2.7 7.1 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit KAP_NTPase PF07693.14 KZN86216.1 - 0.0071 15.6 0.0 0.21 10.8 0.0 2.3 2 0 0 2 2 2 1 KAP family P-loop domain RNA_helicase PF00910.22 KZN86216.1 - 0.01 16.2 0.0 3.5 8.1 0.0 2.5 2 0 0 2 2 2 0 RNA helicase PRK PF00485.18 KZN86216.1 - 0.011 15.5 0.0 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Cytidylate_kin PF02224.18 KZN86216.1 - 0.012 15.3 0.0 4.2 7.0 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase MMR_HSR1 PF01926.23 KZN86216.1 - 0.017 15.2 0.0 7.8 6.6 0.0 3.0 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_14 PF13173.6 KZN86216.1 - 0.018 15.1 0.0 4.4 7.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 KZN86216.1 - 0.037 13.7 0.0 13 5.3 0.0 2.8 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain APS_kinase PF01583.20 KZN86216.1 - 0.044 13.7 0.0 12 5.7 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase IstB_IS21 PF01695.17 KZN86216.1 - 0.045 13.5 1.9 4.8 6.9 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein SbcCD_C PF13558.6 KZN86216.1 - 0.045 14.0 1.8 10 6.4 0.2 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Mg_chelatase PF01078.21 KZN86216.1 - 0.051 13.0 0.0 6.1 6.2 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TniB PF05621.11 KZN86216.1 - 0.07 12.5 0.0 23 4.3 0.0 3.2 4 0 0 4 4 4 0 Bacterial TniB protein AAA_17 PF13207.6 KZN86216.1 - 0.084 13.3 0.0 13 6.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KZN86216.1 - 0.11 12.4 0.2 17 5.3 0.0 3.0 3 0 0 3 3 2 0 NACHT domain ATP_bind_1 PF03029.17 KZN86216.1 - 0.13 12.0 0.0 7.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ADH_N PF08240.12 KZN86217.1 - 0.0023 17.8 0.6 0.0038 17.1 0.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_4 PF07993.12 KZN86218.1 - 2.5e-38 131.7 0.0 3.1e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KZN86218.1 - 0.00064 18.9 0.0 0.0009 18.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KZN86218.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Cation_efflux PF01545.21 KZN86219.1 - 4.5e-46 157.1 12.7 4.5e-46 157.1 12.7 2.4 2 0 0 2 2 2 2 Cation efflux family SPX PF03105.19 KZN86219.1 - 3.4 7.5 15.4 0.89 9.4 3.3 2.5 3 0 0 3 3 3 0 SPX domain Glyco_trans_1_4 PF13692.6 KZN86220.1 - 1.5e-08 35.2 0.0 5.3e-07 30.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KZN86220.1 - 7.2e-05 22.8 0.1 0.00016 21.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KZN86220.1 - 0.22 11.9 0.0 0.42 11.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 TFIIIC_delta PF12657.7 KZN86221.1 - 5.1e-35 121.1 0.7 9.7e-35 120.2 0.7 1.5 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 KZN86221.1 - 2.3e-33 114.1 1.1 4.9e-33 113.1 1.1 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex Thiolase_N PF00108.23 KZN86222.1 - 1.1e-89 300.3 0.4 1.1e-89 300.3 0.4 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KZN86222.1 - 4.1e-38 129.8 1.3 4.1e-38 129.8 1.3 1.9 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KZN86222.1 - 8.1e-06 25.6 1.8 1.3e-05 24.9 0.3 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KZN86222.1 - 3.1 7.7 6.3 5.3 7.0 0.2 3.2 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III UQ_con PF00179.26 KZN86223.1 - 1e-51 174.3 0.0 1.1e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KZN86223.1 - 0.0019 17.9 0.0 0.0022 17.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KZN86223.1 - 0.087 13.1 0.0 0.18 12.1 0.0 1.5 1 1 0 1 1 1 0 RWD domain Kinesin PF00225.23 KZN86224.1 - 4.8e-111 370.9 0.1 1.1e-110 369.7 0.1 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KZN86224.1 - 2.4e-25 89.2 0.0 7.8e-25 87.6 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding STPPase_N PF16891.5 KZN86224.1 - 0.071 13.6 1.7 17 5.9 0.2 3.1 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain ERG2_Sigma1R PF04622.12 KZN86224.1 - 0.11 11.8 0.0 0.3 10.4 0.0 1.7 1 0 0 1 1 1 0 ERG2 and Sigma1 receptor like protein HAP1_N PF04849.13 KZN86224.1 - 1.2 8.3 49.2 0.19 10.9 8.5 4.0 3 2 0 3 3 3 0 HAP1 N-terminal conserved region XkdW PF09636.10 KZN86224.1 - 1.4 9.1 6.0 11 6.2 0.3 3.1 2 0 0 2 2 2 0 XkdW protein Filament PF00038.21 KZN86224.1 - 7.5 6.0 57.2 11 5.5 14.9 4.3 2 1 1 3 3 3 0 Intermediate filament protein EF-hand_1 PF00036.32 KZN86225.1 - 4e-26 88.6 11.2 3.6e-08 32.4 0.1 4.7 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 KZN86225.1 - 2.2e-25 86.4 5.5 3.5e-06 26.5 0.1 5.2 4 1 1 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 KZN86225.1 - 2.6e-24 85.4 7.8 9.2e-16 58.1 0.9 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KZN86225.1 - 2.4e-17 61.6 10.9 0.00016 21.0 0.1 4.7 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 KZN86225.1 - 6.8e-16 57.9 11.1 4.8e-06 26.3 1.1 4.1 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 KZN86225.1 - 6e-09 35.8 5.7 0.0032 17.4 0.2 3.5 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KZN86225.1 - 0.00016 21.9 0.8 0.022 15.1 0.1 3.2 2 1 1 3 3 3 2 EF-hand domain EF-hand_10 PF14788.6 KZN86225.1 - 0.0018 18.1 1.0 0.48 10.3 0.1 3.5 3 1 0 3 3 3 1 EF hand DUF1679 PF07914.11 KZN86225.1 - 0.016 14.1 0.3 1.3 7.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) SPARC_Ca_bdg PF10591.9 KZN86225.1 - 0.024 14.9 2.0 2.1 8.7 0.3 3.2 2 2 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EMP70 PF02990.16 KZN86226.1 - 2.1e-204 680.0 0.1 2.7e-204 679.6 0.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Sas10_Utp3 PF04000.15 KZN86227.1 - 4.7e-17 62.4 0.2 4.7e-17 62.4 0.2 1.9 2 0 0 2 2 2 1 Sas10/Utp3/C1D family TT_ORF2 PF02957.15 KZN86227.1 - 0.42 11.5 6.1 0.51 11.3 0.7 2.6 2 0 0 2 2 2 0 TT viral ORF2 HEXIM PF15313.6 KZN86227.1 - 0.5 10.6 5.6 11 6.2 3.0 2.7 2 0 0 2 2 2 0 Hexamethylene bis-acetamide-inducible protein FMO-like PF00743.19 KZN86229.1 - 6.6e-12 44.6 0.0 1.3e-06 27.1 0.2 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KZN86229.1 - 6.6e-06 25.6 1.0 0.06 12.6 0.3 3.3 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KZN86229.1 - 2.3e-05 23.8 0.0 0.015 14.5 0.3 2.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN86229.1 - 3.4e-05 24.0 0.5 0.00017 21.8 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KZN86229.1 - 0.00022 21.3 0.2 0.073 13.1 0.0 2.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding 3HCDH_N PF02737.18 KZN86229.1 - 0.0016 18.4 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KZN86229.1 - 0.0047 16.2 0.1 0.016 14.5 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KZN86229.1 - 0.0052 16.4 0.4 0.023 14.3 0.2 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KZN86229.1 - 0.006 17.1 0.6 1.2 9.8 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KZN86229.1 - 0.045 12.5 0.3 0.47 9.1 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 KZN86229.1 - 0.063 12.3 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KZN86229.1 - 0.16 11.0 0.3 0.25 10.4 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain K_oxygenase PF13434.6 KZN86229.1 - 0.21 10.7 0.6 32 3.5 0.0 3.4 4 0 0 4 4 4 0 L-lysine 6-monooxygenase (NADPH-requiring) TPR_16 PF13432.6 KZN86230.1 - 0.11 13.2 0.8 0.24 12.1 0.8 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat FAD_binding_4 PF01565.23 KZN86231.1 - 3.5e-13 49.5 0.0 5.5e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain 5_nucleotid_C PF02872.18 KZN86232.1 - 5.8e-36 124.1 0.0 1.1e-35 123.2 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KZN86232.1 - 3.1e-05 24.6 0.5 6e-05 23.6 0.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PD40 PF07676.12 KZN86232.1 - 2.6 8.1 6.8 0.72 9.9 0.1 3.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat FMN_dh PF01070.18 KZN86234.1 - 2.5e-109 365.5 0.0 2.8e-109 365.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KZN86234.1 - 2.5e-05 23.6 0.0 3.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KZN86234.1 - 0.0029 17.0 0.1 0.005 16.3 0.1 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KZN86234.1 - 0.0047 16.0 0.2 0.011 14.8 0.2 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KZN86234.1 - 0.17 11.3 0.0 8 5.8 0.0 2.3 2 0 0 2 2 2 0 Histidine biosynthesis protein Hydantoinase_B PF02538.14 KZN86235.1 - 2.8e-216 718.9 0.2 3.5e-216 718.6 0.2 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KZN86235.1 - 1.9e-102 342.4 0.1 9.3e-101 336.9 0.0 2.2 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KZN86235.1 - 1.1e-58 197.9 0.0 2.1e-55 187.2 0.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Fungal_trans PF04082.18 KZN86236.1 - 2.1e-20 72.9 0.1 3.8e-20 72.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cyclase PF04199.13 KZN86237.1 - 1.2e-14 54.7 0.0 3.3e-14 53.3 0.0 1.5 1 1 1 2 2 2 1 Putative cyclase ADH_N_2 PF16884.5 KZN86237.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Chitin_synth_1 PF01644.17 KZN86238.1 - 1.4e-67 226.7 0.0 2.1e-67 226.2 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KZN86238.1 - 9e-28 96.0 0.1 2.6e-27 94.6 0.1 1.8 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KZN86238.1 - 4.9e-22 78.2 0.1 2.3e-19 69.4 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KZN86238.1 - 8.8e-10 38.8 0.1 8.8e-10 38.8 0.1 2.8 3 1 0 3 3 3 1 Glycosyl transferase family group 2 adh_short PF00106.25 KZN86239.1 - 3.5e-28 98.4 0.0 4.7e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN86239.1 - 1.3e-21 77.3 0.0 1.8e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN86239.1 - 0.00026 21.0 0.1 0.00091 19.2 0.1 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KZN86239.1 - 0.025 14.0 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KZN86239.1 - 0.16 11.1 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KZN86239.1 - 0.17 11.2 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase MFS_1 PF07690.16 KZN86240.1 - 5.4e-37 127.5 43.4 5.4e-37 127.5 43.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DHDPS PF00701.22 KZN86241.1 - 5.4e-39 133.6 0.0 7.1e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family TPR_10 PF13374.6 KZN86241.1 - 0.011 15.6 1.0 0.49 10.3 1.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1682 PF07946.14 KZN86241.1 - 0.088 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Aminotran_1_2 PF00155.21 KZN86242.1 - 1.4e-65 221.9 0.0 1.6e-65 221.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aa_trans PF01490.18 KZN86243.1 - 1.2e-47 162.5 39.7 1.4e-47 162.3 39.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3483 PF11982.8 KZN86243.1 - 3.5 7.2 8.8 1.6 8.3 0.2 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF3483) Aminotran_4 PF01063.19 KZN86245.1 - 2.9e-43 148.3 0.0 3.4e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV BNR_2 PF13088.6 KZN86247.1 - 1.8e-21 76.7 0.7 3.9e-20 72.3 0.7 2.2 1 1 0 1 1 1 1 BNR repeat-like domain BNR_3 PF13859.6 KZN86247.1 - 2.1e-10 40.4 0.0 3.1e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 KZN86247.1 - 2.1e-08 32.9 24.7 0.098 12.7 1.3 6.5 6 0 0 6 6 6 5 BNR/Asp-box repeat DUF4185 PF13810.6 KZN86247.1 - 1.3e-05 24.7 2.7 0.12 11.6 0.0 3.8 1 1 2 4 4 4 2 Domain of unknown function (DUF4185) Sortilin-Vps10 PF15902.5 KZN86247.1 - 0.0016 17.3 8.5 0.0046 15.8 0.2 3.7 2 2 2 4 4 4 2 Sortilin, neurotensin receptor 3, CHB_HEX_C PF03174.13 KZN86247.1 - 0.011 15.6 3.3 3.5 7.7 0.0 4.5 4 1 1 5 5 5 0 Chitobiase/beta-hexosaminidase C-terminal domain DUF5546 PF17700.1 KZN86247.1 - 0.084 13.2 1.4 0.23 11.8 0.0 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5546) DHDPS PF00701.22 KZN86248.1 - 8.1e-41 139.6 0.0 1e-40 139.3 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family NTPase_P4 PF11602.8 KZN86248.1 - 0.13 11.4 0.1 0.2 10.8 0.1 1.2 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 Fungal_trans_2 PF11951.8 KZN86249.1 - 2e-12 46.6 0.0 3.1e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN86249.1 - 2.9e-07 30.5 10.7 4.9e-07 29.8 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 KZN86250.1 - 1.3e-63 214.9 0.0 1.6e-63 214.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NAPRTase_N PF17767.1 KZN86250.1 - 0.038 14.4 1.7 5.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain MFS_1 PF07690.16 KZN86251.1 - 8.8e-33 113.7 28.4 5.8e-32 111.0 27.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PgaD PF13994.6 KZN86251.1 - 0.097 12.7 3.3 0.79 9.8 0.2 2.9 3 1 0 3 3 3 0 PgaD-like protein Transferase PF02458.15 KZN86253.1 - 6.6e-08 31.6 0.0 7.6e-08 31.4 0.0 1.0 1 0 0 1 1 1 1 Transferase family DUF3084 PF11283.8 KZN86254.1 - 0.049 13.6 0.5 0.049 13.6 0.5 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3084) DAO PF01266.24 KZN86255.1 - 7.6e-32 111.3 0.1 1.1e-31 110.7 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KZN86255.1 - 4.7e-07 29.9 0.1 0.015 15.3 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 KZN86255.1 - 1.6e-05 24.2 0.2 0.00011 21.4 0.0 2.2 2 1 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KZN86255.1 - 6.4e-05 22.3 0.1 0.0025 17.1 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KZN86255.1 - 0.00019 20.6 0.3 0.085 11.9 0.1 2.5 2 1 1 3 3 3 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 KZN86255.1 - 0.00084 19.5 0.0 0.0031 17.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KZN86255.1 - 0.0064 15.8 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 KZN86255.1 - 0.01 16.1 0.0 3.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 KZN86255.1 - 0.12 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Het-C PF07217.11 KZN86255.1 - 0.15 10.6 0.0 0.22 10.0 0.0 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C TrkA_N PF02254.18 KZN86255.1 - 0.18 12.1 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain MCRA PF06100.11 KZN86256.1 - 4.1e-109 365.6 0.0 7.2e-80 269.2 0.0 2.0 1 1 1 2 2 2 2 MCRA family DAO PF01266.24 KZN86256.1 - 0.18 11.3 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Aa_trans PF01490.18 KZN86257.1 - 8.2e-78 261.9 24.7 9.6e-78 261.7 24.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Colicin PF01024.19 KZN86257.1 - 0.21 11.4 0.6 0.42 10.5 0.6 1.5 1 0 0 1 1 1 0 Colicin pore forming domain Zn_clus PF00172.18 KZN86258.1 - 1.3e-06 28.4 9.0 2e-06 27.8 9.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN86258.1 - 0.0017 17.4 0.5 0.006 15.6 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain DEC-1_N PF04625.13 KZN86258.1 - 3 6.8 9.9 4.6 6.1 9.9 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Presenilin PF01080.17 KZN86259.1 - 3.6 6.2 5.0 3.7 6.2 5.0 1.1 1 0 0 1 1 1 0 Presenilin zf-C2H2_jaz PF12171.8 KZN86260.1 - 9.4e-38 127.8 14.2 9.7e-05 22.6 0.1 6.8 7 0 0 7 7 6 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KZN86260.1 - 1.9e-35 120.2 8.9 0.0001 22.6 0.2 6.4 6 0 0 6 6 6 6 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KZN86260.1 - 6.9e-24 83.3 2.5 0.042 13.9 0.0 6.5 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KZN86260.1 - 4e-21 73.9 15.8 0.036 14.9 0.1 7.2 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2 PF00096.26 KZN86260.1 - 5.5e-16 58.0 19.4 0.16 12.5 0.1 7.0 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KZN86260.1 - 7.9e-14 51.8 9.2 2.5 8.5 0.0 7.0 2 1 5 7 7 7 6 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KZN86260.1 - 5.8e-11 42.0 12.6 3.4 7.5 0.0 6.6 7 0 0 7 7 6 6 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 KZN86260.1 - 1.3e-07 32.3 8.2 0.87 10.3 0.1 5.3 1 1 4 5 5 5 4 Zinc finger C2H2-type, 3 repeats zf-C2HC_2 PF13913.6 KZN86260.1 - 1.8e-07 30.9 17.4 3.8 7.5 0.0 6.3 6 0 0 6 6 6 1 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 KZN86260.1 - 4.1e-06 27.0 9.0 42 4.8 0.0 7.2 6 0 0 6 6 6 0 Zinc-finger double domain HNH_5 PF14279.6 KZN86260.1 - 9e-05 22.3 12.4 33 4.4 0.0 6.6 6 1 0 6 6 6 0 HNH endonuclease DUF4334 PF14232.6 KZN86260.1 - 0.00043 20.2 0.0 1.3e+02 2.6 0.0 5.0 5 0 0 5 5 5 0 Domain of unknown function (DUF4334) META PF03724.16 KZN86260.1 - 0.0007 19.5 0.0 94 3.0 0.0 5.0 1 1 4 5 5 5 0 META domain LpxD PF04613.14 KZN86260.1 - 0.00078 19.2 0.0 33 4.3 0.0 4.9 1 1 4 5 5 5 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD C1_4 PF07975.12 KZN86260.1 - 0.0013 18.9 16.2 1.4 9.2 0.4 5.5 2 1 4 6 6 6 1 TFIIH C1-like domain ADK_lid PF05191.14 KZN86260.1 - 0.0014 18.6 7.1 98 3.1 0.0 6.1 6 0 0 6 6 6 0 Adenylate kinase, active site lid Spt46 PF17734.1 KZN86260.1 - 0.0046 16.8 2.6 26 4.5 0.0 4.1 1 1 4 5 5 5 0 Spermatogenesis-associated protein 46 Endonuclease_7 PF02945.15 KZN86260.1 - 0.011 15.7 8.7 36 4.4 0.1 5.8 2 1 3 5 5 5 0 Recombination endonuclease VII zf-C2H2_8 PF15909.5 KZN86260.1 - 0.014 15.7 3.6 24 5.3 0.1 3.6 2 1 2 4 4 3 0 C2H2-type zinc ribbon zf-H2C2 PF09337.10 KZN86260.1 - 0.029 14.6 5.3 1.6e+02 2.6 0.0 5.4 5 0 0 5 5 5 0 H2C2 zinc finger RdDM_RDM1 PF09187.10 KZN86260.1 - 0.03 14.4 0.0 55 3.9 0.0 3.2 1 1 2 3 3 3 0 RNA-directed DNA methylation 1 zf_UBZ PF18439.1 KZN86260.1 - 0.087 12.4 22.3 35 4.1 0.1 6.8 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger zf-AN1 PF01428.16 KZN86260.1 - 0.28 11.4 18.0 93 3.3 0.0 6.8 7 0 0 7 7 7 0 AN1-like Zinc finger zf_C2H2_ZHX PF18387.1 KZN86260.1 - 4.4 7.0 12.4 1.1e+02 2.6 0.2 6.0 6 1 1 7 7 7 0 Zinc-fingers and homeoboxes C2H2 finger domain Zip PF02535.22 KZN86261.1 - 9.1e-58 196.1 2.2 1.2e-57 195.6 2.2 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter UNC-50 PF05216.13 KZN86261.1 - 0.49 9.9 3.8 0.55 9.7 1.7 1.9 2 0 0 2 2 2 0 UNC-50 family DUF350 PF03994.14 KZN86261.1 - 5.9 7.1 8.9 6.7 6.9 0.3 3.3 3 0 0 3 3 3 0 Domain of Unknown Function (DUF350) Sugar_tr PF00083.24 KZN86262.1 - 2.2e-78 264.2 22.6 2.4e-78 264.0 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN86262.1 - 3.3e-19 69.0 51.4 9.7e-15 54.3 28.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_43 PF04616.14 KZN86263.1 - 5.3e-37 127.7 3.9 7.1e-37 127.3 3.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Sugar_tr PF00083.24 KZN86264.1 - 9.9e-98 327.9 25.7 1.2e-97 327.7 25.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN86264.1 - 3.7e-25 88.6 27.9 3.7e-25 88.6 27.9 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KZN86264.1 - 1e-05 24.2 2.7 1e-05 24.2 2.7 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ABC_membrane_3 PF13748.6 KZN86264.1 - 6.1 6.0 6.8 2 7.6 0.9 2.4 2 0 0 2 2 2 0 ABC transporter transmembrane region 2OG-FeII_Oxy_3 PF13640.6 KZN86265.1 - 1.5e-09 38.6 0.0 2.6e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily IQ PF00612.27 KZN86266.1 - 0.00061 19.4 1.7 0.0021 17.7 1.7 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif GFA PF04828.14 KZN86267.1 - 5.6e-11 42.6 0.1 5.6e-11 42.6 0.1 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Thiolase_N PF00108.23 KZN86268.1 - 6e-17 61.8 0.0 8.8e-15 54.8 0.0 2.3 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KZN86268.1 - 8.4e-11 41.6 1.4 1.3e-09 37.7 0.0 2.9 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KZN86268.1 - 1.5e-06 27.9 0.0 9.2e-05 22.2 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 KZN86268.1 - 4.9e-05 23.0 0.4 0.00014 21.5 0.4 1.7 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 KZN86268.1 - 0.0021 16.8 0.2 0.0052 15.5 0.0 1.6 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) Acyl-CoA_dh_1 PF00441.24 KZN86269.1 - 1.6e-34 119.3 2.5 2.5e-34 118.6 2.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KZN86269.1 - 2.9e-25 89.1 0.0 6.6e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KZN86269.1 - 4.2e-20 71.7 0.0 7e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KZN86269.1 - 1.2e-12 48.2 0.1 2.9e-12 47.0 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Glucosaminidase PF01832.20 KZN86269.1 - 0.014 15.8 0.0 0.035 14.6 0.0 1.7 1 0 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase DUF2183 PF09949.9 KZN86269.1 - 0.064 13.6 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) CoA_transf_3 PF02515.17 KZN86270.1 - 4.2e-105 351.9 0.0 8e-104 347.7 0.0 2.0 1 1 0 1 1 1 1 CoA-transferase family III Lipase_GDSL_2 PF13472.6 KZN86271.1 - 9.2e-13 49.0 1.2 1.2e-12 48.7 1.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KZN86271.1 - 1.7e-06 28.2 0.1 2.3e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Amidase PF01425.21 KZN86272.1 - 1.8e-12 47.0 0.0 7.2e-06 25.2 0.0 2.4 1 1 1 2 2 2 2 Amidase Fungal_trans_2 PF11951.8 KZN86272.1 - 0.0011 17.9 0.6 0.0027 16.6 0.1 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain Recep_L_domain PF01030.24 KZN86273.1 - 5.8e-05 23.2 0.1 0.031 14.4 0.1 3.0 1 1 1 2 2 2 1 Receptor L domain Ecm33 PF12454.8 KZN86273.1 - 0.00018 21.6 0.8 0.00018 21.6 0.8 2.9 3 0 0 3 3 3 1 GPI-anchored cell wall organization protein VSP PF03302.13 KZN86273.1 - 0.0011 17.9 0.6 0.0011 17.9 0.6 1.6 2 0 0 2 2 2 1 Giardia variant-specific surface protein Adeno_E3_CR2 PF02439.15 KZN86273.1 - 0.0023 17.6 0.1 0.0056 16.4 0.1 1.7 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 KZN86273.1 - 0.012 16.5 0.0 0.031 15.2 0.0 1.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain FeoB_associated PF12669.7 KZN86273.1 - 0.026 14.9 2.8 0.032 14.6 0.2 2.3 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein DUF2434 PF10361.9 KZN86273.1 - 0.084 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) Stevor PF17410.2 KZN86273.1 - 0.11 12.0 0.2 0.2 11.2 0.0 1.5 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame DUF4381 PF14316.6 KZN86273.1 - 0.14 12.3 0.1 0.28 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) RIFIN PF02009.16 KZN86273.1 - 0.19 11.6 0.1 0.35 10.7 0.1 1.3 1 0 0 1 1 1 0 Rifin DUF347 PF03988.12 KZN86273.1 - 0.19 11.9 0.2 0.19 11.9 0.2 1.8 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) CcmD PF04995.14 KZN86273.1 - 6.3 7.0 10.7 0.49 10.5 4.3 2.1 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Aldo_ket_red PF00248.21 KZN86274.1 - 3.7e-28 98.6 0.1 2e-27 96.2 0.1 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family Pro-kuma_activ PF09286.11 KZN86275.1 - 5.4e-46 156.4 0.1 1.1e-45 155.4 0.1 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KZN86275.1 - 0.00038 19.8 0.4 0.00066 19.0 0.4 1.3 1 0 0 1 1 1 1 Subtilase family Response_reg PF00072.24 KZN86276.1 - 1.3e-25 89.8 1.0 2.4e-25 88.9 0.4 1.8 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 KZN86276.1 - 1.7e-25 89.7 0.0 3.7e-25 88.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KZN86276.1 - 1.4e-16 60.2 0.1 3.5e-16 59.0 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 KZN86276.1 - 5.9e-14 52.0 0.0 5.2e-10 39.3 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KZN86276.1 - 2.6e-13 50.1 0.0 1.5e-11 44.5 0.0 2.7 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 KZN86276.1 - 3.3e-11 43.4 0.1 7.2e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 KZN86276.1 - 0.0051 17.1 0.1 0.015 15.6 0.1 1.9 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 KZN86276.1 - 0.0071 16.4 0.0 0.23 11.5 0.0 2.6 2 0 0 2 2 2 1 PAS domain DAO PF01266.24 KZN86277.1 - 1.8e-27 96.9 0.2 2.3e-27 96.5 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.16 KZN86277.1 - 0.018 14.7 0.7 0.043 13.4 0.7 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 KZN86277.1 - 0.033 13.4 0.0 0.13 11.5 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 KZN86277.1 - 0.12 11.7 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 ThiF family DUF604 PF04646.12 KZN86277.1 - 0.15 11.5 0.1 0.24 10.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF604 OPT PF03169.15 KZN86278.1 - 1.3e-169 565.8 58.0 1.5e-169 565.6 58.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3937 PF13073.6 KZN86278.1 - 0.038 14.1 4.2 2.4 8.4 1.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3937) Amidohydro_1 PF01979.20 KZN86279.1 - 3.7e-60 204.1 0.0 4.5e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KZN86279.1 - 1.7e-11 44.3 0.2 4.4e-08 33.0 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 KZN86279.1 - 0.00076 18.9 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Dpy-30 PF05186.13 KZN86279.1 - 0.043 13.5 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Dpy-30 motif Fungal_trans PF04082.18 KZN86280.1 - 1.2e-19 70.4 0.0 2.4e-19 69.4 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN86280.1 - 1.1e-09 38.2 9.5 1.7e-09 37.7 9.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_25 PF01183.20 KZN86281.1 - 4e-41 141.1 0.1 4.7e-41 140.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 p450 PF00067.22 KZN86282.1 - 3.1e-36 125.1 0.0 3.9e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 BOFC_N PF08977.10 KZN86282.1 - 0.11 12.5 0.5 0.25 11.4 0.5 1.5 1 0 0 1 1 1 0 Bypass of Forespore C, N terminal Acetyltransf_10 PF13673.7 KZN86283.1 - 9.6e-06 25.6 0.0 1.8e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KZN86283.1 - 5.8e-05 23.4 0.0 9.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KZN86283.1 - 0.0041 17.4 0.0 0.0058 16.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KZN86283.1 - 0.0097 16.0 0.0 0.031 14.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain 2-Hacid_dh_C PF02826.19 KZN86284.1 - 1.8e-45 154.5 0.0 2.7e-45 153.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KZN86284.1 - 1.1e-06 28.4 0.0 1.4e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KZN86284.1 - 0.0068 16.6 0.1 0.012 15.8 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase SET PF00856.28 KZN86285.1 - 0.0051 17.2 0.0 0.0065 16.9 0.0 1.3 1 0 0 1 1 1 1 SET domain PEX11 PF05648.14 KZN86287.1 - 7.9e-38 130.1 0.1 8.9e-38 130.0 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Rab5ip PF07019.12 KZN86287.1 - 0.046 14.3 3.0 0.27 11.8 2.1 2.4 1 1 2 3 3 3 0 Rab5-interacting protein (Rab5ip) DUF1211 PF06736.11 KZN86287.1 - 0.14 12.6 2.0 0.15 12.5 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1211) F-actin_cap_A PF01267.17 KZN86288.1 - 3.5e-92 308.6 0.0 4e-92 308.4 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Fungal_trans_2 PF11951.8 KZN86290.1 - 6e-76 255.7 2.0 8.6e-76 255.2 2.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Polysacc_deac_1 PF01522.21 KZN86290.1 - 3.4e-17 62.5 0.0 6.8e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KZN86290.1 - 4.8e-08 32.9 0.0 1.4e-07 31.4 0.0 1.8 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) tRNA-synt_2c PF01411.19 KZN86291.1 - 9.5e-10 37.6 0.0 1.2e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KZN86291.1 - 1.2e-06 28.5 0.3 2.4e-06 27.5 0.3 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain PAP2 PF01569.21 KZN86292.1 - 2.4e-28 98.6 1.0 2.4e-28 98.6 1.0 1.9 2 0 0 2 2 2 1 PAP2 superfamily DUF2933 PF11666.8 KZN86292.1 - 0.049 13.7 0.4 0.049 13.7 0.4 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2933) PAP2_3 PF14378.6 KZN86292.1 - 1.9 8.2 12.2 1.2 8.7 8.5 2.5 1 1 1 2 2 2 0 PAP2 superfamily RseC_MucC PF04246.12 KZN86292.1 - 4.6 7.2 7.4 8.6 6.3 0.5 3.0 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Med7 PF05983.11 KZN86293.1 - 4e-62 209.7 3.9 5.4e-62 209.3 3.9 1.2 1 0 0 1 1 1 1 MED7 protein EcoEI_R_C PF08463.10 KZN86293.1 - 0.039 14.1 0.6 0.12 12.4 0.0 2.0 3 0 0 3 3 3 0 EcoEI R protein C-terminal GHMP_kinases_C PF08544.13 KZN86293.1 - 0.14 12.6 0.1 0.35 11.3 0.1 1.7 1 0 0 1 1 1 0 GHMP kinases C terminal Fungal_trans PF04082.18 KZN86294.1 - 4.5e-12 45.6 0.3 9.9e-12 44.4 0.3 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 KZN86294.1 - 0.011 14.6 2.1 0.046 12.5 2.1 1.8 1 1 0 1 1 1 0 Fungal specific transcription factor domain HEAT_EZ PF13513.6 KZN86295.1 - 2.9e-18 66.0 5.9 7.9e-07 29.5 0.0 8.6 8 1 1 9 9 9 3 HEAT-like repeat HEAT PF02985.22 KZN86295.1 - 2e-16 58.6 0.5 0.00029 20.8 0.1 8.5 9 0 0 9 9 8 3 HEAT repeat HEAT_2 PF13646.6 KZN86295.1 - 3.7e-16 59.3 0.9 0.00014 22.2 0.0 7.6 6 2 3 9 9 9 4 HEAT repeats IBN_N PF03810.19 KZN86295.1 - 2.6e-10 40.1 0.9 2.4e-08 33.8 0.1 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cnd1 PF12717.7 KZN86295.1 - 2.6e-10 40.6 3.1 0.0041 17.2 0.1 4.6 4 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KZN86295.1 - 4.2e-10 40.1 0.1 0.29 11.8 0.0 6.3 5 1 1 6 6 6 3 Vacuolar 14 Fab1-binding region IFRD PF05004.13 KZN86295.1 - 8.8e-09 34.9 2.8 0.00059 19.0 0.2 3.9 3 1 1 4 4 4 3 Interferon-related developmental regulator (IFRD) MMS19_C PF12460.8 KZN86295.1 - 1.9e-08 33.9 1.6 0.002 17.3 0.0 3.5 3 1 0 3 3 3 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 KZN86295.1 - 9.8e-07 28.6 0.0 0.0036 16.9 0.0 3.7 4 0 0 4 4 4 2 CLASP N terminal RTP1_C1 PF10363.9 KZN86295.1 - 0.00052 20.2 1.1 6.8 6.9 0.0 4.9 4 1 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 KZN86295.1 - 0.0008 19.4 3.3 0.97 9.6 0.0 5.8 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 KZN86295.1 - 0.0023 17.7 0.0 0.77 9.5 0.0 3.0 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis NUC173 PF08161.12 KZN86295.1 - 0.068 12.8 0.1 29 4.3 0.0 4.9 5 1 2 7 7 7 0 NUC173 domain NPC1_N PF16414.5 KZN86296.1 - 2.7e-83 279.3 6.6 3.8e-83 278.8 6.6 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 KZN86296.1 - 7.7e-78 262.4 4.5 5.7e-49 167.0 0.0 2.1 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 KZN86296.1 - 3e-50 170.0 7.4 3e-50 170.0 7.4 3.1 3 1 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 KZN86296.1 - 0.00019 20.5 13.7 0.00019 20.5 13.7 3.5 3 2 0 3 3 3 1 MMPL family Folate_rec PF03024.14 KZN86296.1 - 0.0099 15.8 3.6 0.019 14.8 3.6 1.4 1 0 0 1 1 1 1 Folate receptor family REV1_C PF16727.5 KZN86296.1 - 0.17 12.3 0.2 0.38 11.2 0.2 1.5 1 0 0 1 1 1 0 DNA repair protein REV1 C-terminal domain Tudor_3 PF18115.1 KZN86297.1 - 3.7e-07 29.9 0.0 6.9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 KZN86297.1 - 0.0035 17.4 0.0 0.006 16.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) LBR_tudor PF09465.10 KZN86297.1 - 0.16 11.8 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain PAP1 PF08601.10 KZN86298.1 - 4.4e-127 424.8 37.4 4.5e-126 421.5 21.6 3.8 2 1 1 3 3 3 2 Transcription factor PAP1 bZIP_1 PF00170.21 KZN86298.1 - 6e-07 29.5 9.8 1.3e-06 28.4 9.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor ERM PF00769.19 KZN86298.1 - 0.00023 21.0 1.2 0.00023 21.0 1.2 1.8 2 0 0 2 2 2 1 Ezrin/radixin/moesin family SHE3 PF17078.5 KZN86298.1 - 0.0033 17.2 2.3 0.006 16.3 2.3 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 MbeD_MobD PF04899.12 KZN86298.1 - 0.017 15.2 2.1 0.035 14.2 2.1 1.5 1 0 0 1 1 1 0 MbeD/MobD like bZIP_Maf PF03131.17 KZN86298.1 - 0.24 11.9 10.0 0.49 10.9 10.0 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF2514 PF10721.9 KZN86298.1 - 0.41 10.7 4.2 0.85 9.6 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Apt1 PF10351.9 KZN86298.1 - 0.45 9.3 10.3 0.047 12.6 1.6 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain ABC_tran_Xtn PF12848.7 KZN86298.1 - 4.4 7.4 7.3 9.9 6.3 7.3 1.6 1 0 0 1 1 1 0 ABC transporter SVIP PF15811.5 KZN86298.1 - 5.4 7.5 9.9 13 6.4 9.9 1.6 1 0 0 1 1 1 0 Small VCP/p97-interacting protein DUF2433 PF10360.9 KZN86299.1 - 7.1e-47 158.6 0.0 1.2e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.7 KZN86299.1 - 0.00072 19.8 0.0 0.0026 18.0 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KZN86299.1 - 0.00093 19.7 0.0 0.0025 18.3 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4965 PF16335.5 KZN86300.1 - 1.5e-67 226.6 0.1 2.5e-67 225.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 KZN86300.1 - 2.7e-62 210.5 0.0 5.3e-62 209.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 KZN86300.1 - 5.8e-48 163.5 0.1 2.2e-47 161.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KZN86300.1 - 2.8e-10 39.6 0.1 5.6e-10 38.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Glyco_hydr_116N PF12215.8 KZN86300.1 - 0.024 14.1 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term GFO_IDH_MocA PF01408.22 KZN86301.1 - 4.2e-22 79.2 0.1 6.7e-22 78.6 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KZN86301.1 - 4.1e-06 26.8 0.0 8e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DapB_N PF01113.20 KZN86301.1 - 0.022 14.9 0.0 0.3 11.2 0.0 2.3 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus TRAUB PF08164.12 KZN86302.1 - 2.9e-30 104.6 0.9 1.2e-29 102.7 0.0 2.6 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KZN86302.1 - 1.5e-25 90.5 1.2 1.5e-25 90.5 1.2 2.6 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor ParA PF10609.9 KZN86303.1 - 4.2e-84 281.8 0.1 1.3e-83 280.2 0.1 1.7 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KZN86303.1 - 4.7e-13 49.3 0.0 6e-12 45.7 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KZN86303.1 - 2.5e-09 37.3 1.7 2.2e-08 34.2 1.7 2.0 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 KZN86303.1 - 2.4e-05 23.8 0.1 3.8e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 KZN86303.1 - 0.001 18.3 0.9 0.0044 16.3 0.3 2.1 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_25 PF13481.6 KZN86303.1 - 0.0019 17.8 0.0 0.0041 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 KZN86303.1 - 0.066 12.6 0.0 0.56 9.6 0.0 2.0 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Abhydrolase_3 PF07859.13 KZN86304.1 - 2.2e-40 138.8 0.0 1.9e-32 112.8 0.0 3.4 4 0 0 4 4 4 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KZN86304.1 - 1.1e-13 50.8 0.0 1.8e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Beta_helix_2 PF18835.1 KZN86305.1 - 0.073 12.8 0.5 0.15 11.8 0.5 1.5 1 0 0 1 1 1 0 Beta helix repeat of Inulin fructotransferase Croc_4 PF17691.1 KZN86305.1 - 0.094 12.8 0.2 0.38 10.8 0.0 2.0 2 0 0 2 2 2 0 Contingent replication of cDNA 4 adh_short PF00106.25 KZN86306.1 - 8.2e-27 93.9 0.0 1.1e-26 93.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN86306.1 - 3.4e-20 72.6 0.0 4.5e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN86306.1 - 1.3e-06 28.5 0.0 1.9e-06 27.9 0.0 1.3 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KZN86306.1 - 5.9e-05 23.0 0.3 9.7e-05 22.3 0.3 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KZN86306.1 - 0.00068 19.2 0.0 0.012 15.0 0.1 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family SoPB_HTH PF18090.1 KZN86306.1 - 0.073 13.2 0.1 0.43 10.7 0.0 2.2 2 0 0 2 2 2 0 Centromere-binding protein HTH domain DUF1776 PF08643.10 KZN86306.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Amidase PF01425.21 KZN86307.1 - 3e-30 105.6 0.5 5.3e-30 104.8 0.5 1.3 1 0 0 1 1 1 1 Amidase DAO PF01266.24 KZN86308.1 - 1.3e-25 90.7 0.0 2.3e-25 89.9 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KZN86308.1 - 6.6e-08 32.1 0.0 0.00058 19.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KZN86308.1 - 5e-06 27.0 0.0 1.2e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN86308.1 - 7.4e-06 26.1 0.1 2e-05 24.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 KZN86308.1 - 0.0045 16.9 0.0 0.0069 16.3 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KZN86308.1 - 0.0078 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.6 KZN86308.1 - 0.0097 15.9 0.1 1.4 8.9 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_2 PF03446.15 KZN86308.1 - 0.011 15.9 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.22 KZN86308.1 - 0.022 13.8 0.0 0.75 8.8 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.18 KZN86308.1 - 0.067 13.5 0.2 0.2 11.9 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain HI0933_like PF03486.14 KZN86308.1 - 0.068 11.9 0.1 0.71 8.5 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 KZN86308.1 - 0.074 12.1 0.0 0.2 10.7 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 KZN86308.1 - 0.17 11.1 0.0 7.8 5.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KZN86308.1 - 0.19 11.4 0.0 0.49 10.0 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Cerato-platanin PF07249.12 KZN86309.1 - 4.2e-49 165.6 1.0 4.9e-49 165.4 1.0 1.1 1 0 0 1 1 1 1 Cerato-platanin Glyco_hydro_49 PF03718.13 KZN86309.1 - 0.067 13.2 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 49 Barwin PF00967.17 KZN86309.1 - 0.076 12.9 0.2 0.1 12.5 0.2 1.4 1 1 0 1 1 1 0 Barwin family Pyr_redox_2 PF07992.14 KZN86310.1 - 1.6e-09 37.5 0.0 3.6e-09 36.3 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN86310.1 - 0.00033 20.8 0.0 0.0009 19.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KZN86310.1 - 0.016 15.2 0.0 0.064 13.2 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KZN86310.1 - 0.036 12.8 0.0 0.056 12.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_7 PF13241.6 KZN86310.1 - 0.059 13.8 0.0 4.1 7.9 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KZN86310.1 - 0.083 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KZN86310.1 - 0.19 10.9 0.1 23 4.1 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase YwiC PF14256.6 KZN86311.1 - 0.69 10.2 4.1 0.23 11.7 0.9 1.7 1 1 1 2 2 2 0 YwiC-like protein Sec62 PF03839.16 KZN86313.1 - 7.1e-78 261.0 1.3 7.1e-78 261.0 1.3 2.0 2 0 0 2 2 2 1 Translocation protein Sec62 PROL5-SMR PF15621.6 KZN86313.1 - 3.1 8.4 6.8 0.57 10.7 1.3 2.3 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family CCDC53 PF10152.9 KZN86313.1 - 4.3 7.7 0.0 4.3 7.7 0.0 3.0 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex Pterin_4a PF01329.19 KZN86314.1 - 1.4e-22 79.7 0.2 1.6e-22 79.4 0.2 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase bZIP_2 PF07716.15 KZN86315.1 - 4.5e-06 26.6 5.8 6.5e-06 26.1 5.8 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KZN86315.1 - 6.3e-06 26.2 6.9 8.8e-06 25.7 6.9 1.2 1 0 0 1 1 1 1 bZIP transcription factor UPF0564 PF10595.9 KZN86315.1 - 0.01 14.9 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 bZIP_Maf PF03131.17 KZN86315.1 - 0.013 16.0 4.3 0.019 15.5 4.3 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor WD40_alt PF14077.6 KZN86315.1 - 0.018 14.9 0.3 1.2 9.0 0.0 2.3 1 1 1 2 2 2 0 Alternative WD40 repeat motif CASP_C PF08172.12 KZN86315.1 - 0.022 14.1 0.6 0.029 13.7 0.6 1.1 1 0 0 1 1 1 0 CASP C terminal DivIC PF04977.15 KZN86315.1 - 0.17 11.6 1.4 0.36 10.6 1.4 1.5 1 0 0 1 1 1 0 Septum formation initiator N-SET PF11764.8 KZN86315.1 - 0.21 11.7 3.6 0.31 11.1 3.6 1.1 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N Zn_clus PF00172.18 KZN86316.1 - 2.9e-07 30.5 8.4 2.9e-07 30.5 8.4 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KZN86316.1 - 0.045 14.2 1.3 0.19 12.3 1.0 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KZN86316.1 - 0.31 12.0 1.4 1.4 9.9 1.4 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger Opy2 PF09463.10 KZN86316.1 - 0.33 11.3 5.7 1 9.7 5.7 1.8 1 0 0 1 1 1 0 Opy2 protein MFS_1 PF07690.16 KZN86317.1 - 1.4e-23 83.4 29.6 4.6e-23 81.7 27.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2046 PF09755.9 KZN86318.1 - 0.017 14.4 2.3 0.023 14.0 0.9 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DMSP_lyase PF16867.5 KZN86318.1 - 0.047 13.3 1.4 0.091 12.4 1.1 1.6 1 1 0 1 1 1 0 Dimethlysulfonioproprionate lyase Atg14 PF10186.9 KZN86318.1 - 0.23 10.5 3.1 0.12 11.4 0.6 1.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 MerR-DNA-bind PF09278.11 KZN86318.1 - 1.6 9.3 7.1 1.7 9.2 0.1 2.3 2 0 0 2 2 2 0 MerR, DNA binding TFIIA PF03153.13 KZN86318.1 - 4 7.3 10.0 4.8 7.1 10.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2968 PF11180.8 KZN86318.1 - 8.6 6.0 14.6 4.2 7.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Carn_acyltransf PF00755.20 KZN86320.1 - 7.6e-205 682.0 0.0 8.7e-205 681.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Rxt3 PF08642.10 KZN86321.1 - 1.3e-42 145.6 0.0 3.9e-42 144.0 0.0 1.9 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 KZN86321.1 - 0.0036 17.4 0.0 0.0092 16.1 0.0 1.6 1 0 0 1 1 1 1 LCCL domain MIP PF00230.20 KZN86322.1 - 6.3e-23 81.7 4.5 1.1e-20 74.3 4.5 2.1 1 1 0 1 1 1 1 Major intrinsic protein AAA_11 PF13086.6 KZN86323.1 - 1e-16 61.5 0.0 1.2e-16 61.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 KZN86323.1 - 5.3e-08 32.7 0.0 1.1e-07 31.7 0.0 1.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KZN86323.1 - 0.039 13.7 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase APH PF01636.23 KZN86325.1 - 6.6e-09 36.0 0.0 2e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family DAO PF01266.24 KZN86326.1 - 4.9e-46 157.9 1.3 5.7e-46 157.7 1.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KZN86326.1 - 0.0049 16.1 0.0 0.0092 15.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KZN86326.1 - 0.0051 16.8 2.1 0.3 11.1 0.2 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KZN86326.1 - 0.16 11.0 5.7 4.4 6.3 5.7 2.2 1 1 0 1 1 1 0 FAD binding domain GvpK PF05121.12 KZN86327.1 - 0.057 13.5 0.6 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 Gas vesicle protein K Hydrolase PF00702.26 KZN86328.1 - 7.9e-07 29.6 0.0 2.8e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KZN86328.1 - 0.0038 17.3 0.0 0.0054 16.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 KZN86328.1 - 0.019 15.4 2.6 0.02 15.3 0.8 1.9 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KZN86328.1 - 0.13 12.4 0.0 10 6.3 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase AA_permease PF00324.21 KZN86329.1 - 1.9e-98 330.2 38.2 2.3e-98 329.9 38.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KZN86329.1 - 1.1e-24 87.0 40.2 1.4e-24 86.8 40.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF543 PF04418.12 KZN86329.1 - 4.4 7.4 6.3 31 4.7 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF543) Fungal_trans PF04082.18 KZN86330.1 - 4.4e-19 68.5 0.1 7.1e-19 67.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN86330.1 - 4.1e-07 30.0 8.5 1e-06 28.7 8.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_16 PF13191.6 KZN86331.1 - 0.0021 18.5 0.3 0.012 16.0 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KZN86331.1 - 0.03 14.5 0.0 0.047 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KZN86331.1 - 0.17 11.3 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Wzy_C PF04932.15 KZN86332.1 - 0.099 12.3 1.9 0.12 12.0 1.9 1.4 1 0 0 1 1 1 0 O-Antigen ligase DUF1772 PF08592.11 KZN86332.1 - 0.45 10.8 5.7 0.53 10.6 5.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) MFS_1 PF07690.16 KZN86333.1 - 9.6e-37 126.7 59.5 1.3e-26 93.4 30.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily CLN3 PF02487.17 KZN86334.1 - 4.1e-157 523.3 3.1 4.1e-157 523.3 3.1 1.4 2 0 0 2 2 2 1 CLN3 protein Abhydrolase_3 PF07859.13 KZN86334.1 - 2.3e-33 115.9 0.0 7.9e-23 81.4 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold MFS_1 PF07690.16 KZN86334.1 - 2.8 6.8 31.4 0.017 14.0 3.9 3.0 1 1 1 2 2 2 0 Major Facilitator Superfamily Aminotran_3 PF00202.21 KZN86335.1 - 7.1e-113 377.3 0.0 9e-113 377.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KZN86335.1 - 0.00022 20.5 0.0 0.00041 19.6 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II DUF1674 PF07896.12 KZN86336.1 - 4e-19 68.8 2.5 9.8e-19 67.6 2.5 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) APH PF01636.23 KZN86337.1 - 7.1e-21 75.2 0.0 1.2e-20 74.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Hva1_TUDOR PF11160.8 KZN86338.1 - 1.2e-17 63.8 0.3 1.3e-17 63.6 0.3 1.0 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain Hexokinase_2 PF03727.16 KZN86339.1 - 5.7e-73 245.3 0.0 7.4e-73 244.9 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KZN86339.1 - 1.2e-56 191.7 0.0 5.2e-36 124.4 0.0 2.2 1 1 1 2 2 2 2 Hexokinase Neugrin PF06413.11 KZN86340.1 - 6e-12 46.1 0.3 6e-12 46.1 0.3 1.8 2 1 0 2 2 2 1 Neugrin MRP-L20 PF12824.7 KZN86340.1 - 2.5e-05 24.5 9.3 6.5e-05 23.2 8.7 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_11 PF08279.12 KZN86340.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 HTH domain Acyl-CoA_dh_N PF02771.16 KZN86340.1 - 2.3 8.9 4.1 2 9.1 0.2 2.2 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain Rgp1 PF08737.10 KZN86341.1 - 1.1e-137 459.7 0.0 1.7e-137 459.0 0.0 1.3 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.29 KZN86341.1 - 4e-05 23.7 0.0 0.00011 22.3 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KZN86341.1 - 0.024 15.1 0.0 0.14 12.6 0.0 2.3 3 0 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain Mob1_phocein PF03637.17 KZN86342.1 - 6.7e-73 244.3 0.1 8.8e-73 243.9 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family OSCP PF00213.18 KZN86343.1 - 3e-43 147.9 3.1 3.5e-43 147.7 3.1 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit ACT_6 PF13740.6 KZN86343.1 - 0.1 12.6 0.1 1.8 8.6 0.0 2.7 2 1 1 3 3 3 0 ACT domain DUF148 PF02520.17 KZN86343.1 - 0.1 12.7 0.1 0.23 11.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF148 Glyco_hydro_63 PF03200.16 KZN86344.1 - 2.3e-05 23.3 1.1 2.3e-05 23.3 1.1 4.1 4 1 0 4 4 4 1 Glycosyl hydrolase family 63 C-terminal domain OrfB_IS605 PF01385.19 KZN86345.1 - 0.013 15.7 0.4 0.019 15.2 0.4 1.2 1 0 0 1 1 1 0 Probable transposase DUF4407 PF14362.6 KZN86345.1 - 0.045 13.1 7.1 0.048 13.0 7.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2730 PF10805.8 KZN86345.1 - 0.1 12.7 1.0 1.4 9.1 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) FAM76 PF16046.5 KZN86345.1 - 0.11 11.8 5.3 0.095 12.0 4.7 1.3 1 1 0 1 1 1 0 FAM76 protein Pox_A_type_inc PF04508.12 KZN86345.1 - 0.54 10.2 6.4 1.2 9.1 6.4 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat SlyX PF04102.12 KZN86345.1 - 0.62 10.7 8.2 0.94 10.1 8.2 1.5 1 1 0 1 1 1 0 SlyX Bromodomain PF00439.25 KZN86346.1 - 4.3e-08 33.1 0.0 3.7e-07 30.1 0.0 2.2 1 1 0 1 1 1 1 Bromodomain Diphthamide_syn PF01866.17 KZN86347.1 - 7.6e-118 393.4 0.0 1e-117 392.9 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein HMGL-like PF00682.19 KZN86348.1 - 3.6e-45 154.6 1.3 5.9e-45 153.9 1.3 1.4 1 1 0 1 1 1 1 HMGL-like PE PF00934.20 KZN86348.1 - 0.23 11.8 0.2 0.23 11.8 0.2 2.4 2 0 0 2 2 2 0 PE family WD40 PF00400.32 KZN86349.1 - 8.1e-17 61.3 9.9 0.0093 16.8 0.0 9.3 10 0 0 10 10 10 5 WD domain, G-beta repeat DUF742 PF05331.11 KZN86349.1 - 0.013 15.3 0.0 0.14 12.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF742) SPO22 PF08631.10 KZN86350.1 - 5e-37 127.9 0.0 1.3e-35 123.3 0.0 3.0 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.6 KZN86350.1 - 0.026 14.8 0.5 13 6.2 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KZN86350.1 - 0.04 14.4 3.8 0.094 13.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat CENP-Q PF13094.6 KZN86352.1 - 5.1e-50 170.0 4.3 7e-50 169.5 4.3 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit HAP1_N PF04849.13 KZN86352.1 - 0.011 15.0 2.9 0.015 14.5 2.9 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF5622 PF18533.1 KZN86352.1 - 0.087 13.0 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5622) DUF1843 PF08898.10 KZN86352.1 - 1 9.9 5.4 1.7 9.2 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) HLH PF00010.26 KZN86353.1 - 1.9e-06 27.7 0.0 3.8e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ORC6 PF05460.13 KZN86353.1 - 4.4 6.5 8.8 2.7 7.2 6.9 1.5 1 1 1 2 2 2 0 Origin recognition complex subunit 6 (ORC6) TMEM135_C_rich PF15982.5 KZN86354.1 - 2.2e-05 25.1 1.9 0.00021 21.9 1.1 2.6 2 1 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 Cation_ATPase_C PF00689.21 KZN86354.1 - 0.049 13.3 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus TetR_C_15 PF17918.1 KZN86354.1 - 0.12 13.2 1.3 0.28 12.0 0.1 2.2 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain CtaG_Cox11 PF04442.14 KZN86355.1 - 2.8e-60 202.7 0.0 3.7e-60 202.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DNA_pol3_delta2 PF13177.6 KZN86356.1 - 2.1e-10 40.6 0.0 4.8e-10 39.5 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KZN86356.1 - 2e-06 28.2 0.1 4.7e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KZN86356.1 - 2.7e-05 24.5 0.4 0.00013 22.3 0.2 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KZN86356.1 - 0.00077 19.9 1.1 0.0077 16.6 0.5 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 KZN86356.1 - 0.0036 17.0 0.3 0.009 15.8 0.3 1.6 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 KZN86356.1 - 0.0083 16.1 0.0 0.027 14.4 0.0 1.8 2 0 0 2 2 2 1 Rad17 P-loop domain Rep_fac_C PF08542.11 KZN86356.1 - 0.032 14.6 0.1 0.13 12.7 0.0 2.0 2 0 0 2 2 2 0 Replication factor C C-terminal domain ABC_tran PF00005.27 KZN86356.1 - 0.072 13.6 0.0 0.19 12.3 0.0 1.6 1 1 0 1 1 1 0 ABC transporter T4SS-DNA_transf PF02534.14 KZN86356.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Ribosomal_L16 PF00252.18 KZN86358.1 - 9.4e-32 109.8 0.1 1.2e-31 109.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RFC1 PF08519.12 KZN86359.1 - 4.5e-58 195.9 0.1 1.6e-57 194.1 0.1 2.0 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KZN86359.1 - 8.8e-14 51.6 0.0 2.9e-13 50.0 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KZN86359.1 - 6.2e-10 39.6 0.1 1.7e-09 38.2 0.1 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KZN86359.1 - 5.5e-06 26.4 0.0 1.6e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KZN86359.1 - 1.9e-05 25.0 0.0 5.1e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KZN86359.1 - 0.0008 19.2 0.3 0.0036 17.0 0.2 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KZN86359.1 - 0.0024 18.3 0.1 0.016 15.6 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KZN86359.1 - 0.0045 17.2 1.6 0.0064 16.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KZN86359.1 - 0.0057 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DTHCT PF08070.11 KZN86359.1 - 0.0082 16.9 10.0 0.0082 16.9 10.0 6.7 3 2 3 6 6 2 1 DTHCT (NUC029) region AAA_18 PF13238.6 KZN86359.1 - 0.01 16.4 0.1 0.056 14.0 0.1 2.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KZN86359.1 - 0.012 15.6 0.0 0.036 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KZN86359.1 - 0.043 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 KZN86359.1 - 0.071 13.0 0.9 0.51 10.2 0.1 2.3 1 1 1 2 2 2 0 NTPase NACHT PF05729.12 KZN86359.1 - 0.087 12.7 0.1 0.33 10.9 0.1 2.0 1 1 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 KZN86359.1 - 1.1 9.5 4.0 0.28 11.4 0.1 2.0 2 0 0 2 2 1 0 AAA domain CRIM PF16978.5 KZN86360.1 - 1.3e-40 138.8 0.0 2.4e-40 138.0 0.0 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 KZN86360.1 - 2.4e-25 88.9 0.1 4.4e-25 88.1 0.1 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology SWIRM-assoc_2 PF16496.5 KZN86360.1 - 3.4 6.4 12.6 8.9 5.1 12.6 1.8 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Lectin_leg-like PF03388.13 KZN86362.1 - 3.6e-65 219.5 0.0 4.7e-65 219.2 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family PBP1_TM PF14812.6 KZN86362.1 - 0.028 14.8 0.0 0.051 13.9 0.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PAP_PilO PF06864.12 KZN86362.1 - 0.11 11.2 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Pilin accessory protein (PilO) zf-Tim10_DDP PF02953.15 KZN86363.1 - 2.5e-21 75.1 1.0 3.2e-21 74.7 1.0 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Pkinase PF00069.25 KZN86364.1 - 5.1e-71 239.1 0.0 6.4e-71 238.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN86364.1 - 4.6e-37 127.7 0.0 6.3e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KZN86364.1 - 1.8e-06 27.5 0.0 3.7e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like dbPDZ_assoc PF16610.5 KZN86364.1 - 0.01 16.0 3.0 0.018 15.3 3.0 1.3 1 0 0 1 1 1 0 Unstructured region between two PDZ domains on Dlg5 APH PF01636.23 KZN86364.1 - 0.014 15.3 0.1 0.037 13.9 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family FDF PF09532.10 KZN86364.1 - 0.029 15.2 1.0 0.058 14.3 1.0 1.4 1 0 0 1 1 1 0 FDF domain PRCC PF10253.9 KZN86365.1 - 4.7e-37 128.9 7.1 4.7e-37 128.9 7.1 3.2 2 2 1 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting AAA_5 PF07728.14 KZN86366.1 - 2.5e-128 422.7 0.1 7.6e-22 77.8 0.0 9.7 8 1 1 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KZN86366.1 - 4.1e-49 165.2 7.2 7.6e-18 64.7 0.0 5.6 5 0 0 5 5 4 4 Midasin AAA lid domain AAA_7 PF12775.7 KZN86366.1 - 3.8e-30 104.7 1.1 1.8e-05 24.4 0.0 7.3 7 0 0 7 7 7 6 P-loop containing dynein motor region AAA_3 PF07726.11 KZN86366.1 - 1.3e-29 102.7 0.0 8.7e-11 41.8 0.0 7.3 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 KZN86366.1 - 2.4e-29 101.5 0.1 1.4e-27 95.9 0.0 3.0 2 0 0 2 2 2 1 Midasin AAA lid domain AAA PF00004.29 KZN86366.1 - 3.2e-28 98.8 0.0 0.00028 21.3 0.0 6.9 6 0 0 6 6 6 6 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KZN86366.1 - 4.1e-26 92.4 9.4 5.6e-05 23.6 0.1 8.5 6 1 0 6 6 6 5 AAA ATPase domain Dynein_heavy PF03028.15 KZN86366.1 - 7.3e-23 80.9 0.0 8.2e-06 25.9 0.0 7.6 8 0 0 8 8 7 4 Dynein heavy chain region D6 P-loop domain AAA_33 PF13671.6 KZN86366.1 - 1.2e-19 70.9 0.0 0.00079 19.6 0.0 6.9 6 0 0 6 6 6 3 AAA domain AAA_30 PF13604.6 KZN86366.1 - 5e-19 68.8 0.0 0.0047 16.7 0.0 7.4 6 2 0 6 6 6 4 AAA domain AAA_22 PF13401.6 KZN86366.1 - 4e-18 66.0 0.4 0.063 13.6 0.0 7.9 7 0 0 7 7 6 4 AAA domain AAA_18 PF13238.6 KZN86366.1 - 2.9e-17 63.4 0.3 0.033 14.7 0.0 7.3 6 0 0 6 6 6 3 AAA domain AAA_14 PF13173.6 KZN86366.1 - 1.2e-16 60.9 0.0 0.012 15.6 0.0 7.2 7 0 0 7 7 6 3 AAA domain ABC_tran PF00005.27 KZN86366.1 - 8.7e-16 58.7 0.7 0.0039 17.7 0.0 7.0 6 0 0 6 6 6 3 ABC transporter TsaE PF02367.17 KZN86366.1 - 2e-15 56.9 4.5 0.16 12.0 0.0 6.7 6 0 0 6 6 6 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_6 PF12774.7 KZN86366.1 - 3e-15 56.0 0.0 0.074 12.0 0.0 8.1 8 0 0 8 8 8 3 Hydrolytic ATP binding site of dynein motor region Zeta_toxin PF06414.12 KZN86366.1 - 7e-14 51.6 1.6 0.78 9.0 0.0 7.8 7 0 0 7 7 7 3 Zeta toxin Sigma54_activat PF00158.26 KZN86366.1 - 7.1e-14 51.9 0.0 0.011 15.5 0.0 5.8 6 0 0 6 6 6 3 Sigma-54 interaction domain RNA_helicase PF00910.22 KZN86366.1 - 8.9e-13 48.6 0.9 0.91 9.9 0.0 6.7 6 0 0 6 6 6 3 RNA helicase Mg_chelatase PF01078.21 KZN86366.1 - 9.6e-13 48.0 0.4 1.9 7.8 0.0 8.7 9 0 0 9 9 9 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KZN86366.1 - 1.9e-11 44.2 11.1 0.076 12.9 0.1 6.5 7 0 0 7 7 5 4 NACHT domain SRP54 PF00448.22 KZN86366.1 - 2.1e-11 43.8 3.5 0.072 12.7 0.0 6.2 7 0 0 7 7 6 2 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 KZN86366.1 - 2.7e-11 43.6 2.1 0.081 12.8 0.1 6.3 6 0 0 6 6 6 2 RsgA GTPase RuvB_N PF05496.12 KZN86366.1 - 2.8e-11 43.4 6.5 0.34 10.7 0.0 7.2 7 0 0 7 7 7 3 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 KZN86366.1 - 3.6e-10 40.4 3.1 0.52 10.7 0.0 6.7 7 0 0 7 7 5 1 AAA domain AAA_28 PF13521.6 KZN86366.1 - 3.9e-10 40.2 4.5 0.24 11.6 0.0 6.9 6 0 0 6 6 6 2 AAA domain MMR_HSR1 PF01926.23 KZN86366.1 - 2.3e-09 37.3 1.8 0.039 14.0 0.0 6.6 6 0 0 6 6 6 1 50S ribosome-binding GTPase Sigma54_activ_2 PF14532.6 KZN86366.1 - 2.5e-09 37.4 0.4 0.09 12.9 0.1 5.4 5 0 0 5 5 5 2 Sigma-54 interaction domain ATPase_2 PF01637.18 KZN86366.1 - 6.3e-09 36.1 0.1 1.5 8.7 0.0 6.1 6 0 0 6 6 6 1 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 KZN86366.1 - 7.8e-09 35.4 3.6 0.12 12.1 0.0 5.9 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 KZN86366.1 - 8.8e-09 35.5 0.3 0.27 11.1 0.0 5.6 5 0 0 5 5 5 1 Rad17 P-loop domain DUF815 PF05673.13 KZN86366.1 - 3.4e-08 33.0 1.5 0.58 9.3 0.0 5.6 6 0 0 6 6 6 3 Protein of unknown function (DUF815) AAA_25 PF13481.6 KZN86366.1 - 3.5e-08 33.3 5.5 2.1 7.9 0.0 6.3 7 0 0 7 7 5 2 AAA domain Roc PF08477.13 KZN86366.1 - 7.7e-08 32.6 1.6 11 6.3 0.0 6.4 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 KZN86366.1 - 1e-07 31.9 0.1 1.1 8.9 0.0 5.6 5 0 0 5 5 5 1 IstB-like ATP binding protein AAA_29 PF13555.6 KZN86366.1 - 1.4e-07 31.2 2.7 1.6 8.6 0.0 6.3 6 0 0 6 6 6 1 P-loop containing region of AAA domain T2SSE PF00437.20 KZN86366.1 - 1.7e-07 30.6 2.2 0.23 10.5 0.0 5.6 6 0 0 6 6 5 1 Type II/IV secretion system protein TniB PF05621.11 KZN86366.1 - 3.7e-07 29.7 0.1 1.9 7.9 0.0 5.8 6 0 0 6 6 5 1 Bacterial TniB protein MCM PF00493.23 KZN86366.1 - 4.5e-07 29.2 0.0 1.2 8.2 0.0 5.0 5 0 0 5 5 5 1 MCM P-loop domain AAA_24 PF13479.6 KZN86366.1 - 7.3e-07 29.1 0.1 2.7 7.7 0.0 5.9 6 0 0 6 6 6 1 AAA domain Viral_helicase1 PF01443.18 KZN86366.1 - 1.7e-06 27.9 0.1 0.32 10.7 0.0 5.1 5 0 0 5 5 5 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 KZN86366.1 - 3.4e-06 27.1 5.6 2.5 8.0 0.1 5.5 5 0 0 5 5 5 1 NTPase ATP_bind_1 PF03029.17 KZN86366.1 - 4.1e-06 26.7 2.6 3.1 7.5 0.0 5.9 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein AAA_9 PF12781.7 KZN86366.1 - 1.3e-05 24.4 0.0 0.064 12.4 0.0 4.6 5 0 0 5 5 5 1 ATP-binding dynein motor region SRPRB PF09439.10 KZN86366.1 - 1.5e-05 24.5 3.7 2.4 7.6 0.0 6.0 6 0 0 6 6 6 1 Signal recognition particle receptor beta subunit Bac_DnaA PF00308.18 KZN86366.1 - 1.7e-05 24.8 0.1 1.5 8.6 0.0 4.0 4 0 0 4 4 3 1 Bacterial dnaA protein ResIII PF04851.15 KZN86366.1 - 5.9e-05 23.1 0.2 2 8.4 0.0 4.7 5 0 0 5 5 4 1 Type III restriction enzyme, res subunit cobW PF02492.19 KZN86366.1 - 0.0001 22.0 6.9 3.3 7.3 0.1 6.1 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain PhoH PF02562.16 KZN86366.1 - 0.00019 20.9 0.4 1.7 8.1 0.0 4.3 4 0 0 4 4 4 1 PhoH-like protein CbiA PF01656.23 KZN86366.1 - 0.0002 21.4 0.0 0.69 10.0 0.0 4.1 4 0 0 4 4 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain TIP49 PF06068.13 KZN86366.1 - 0.00037 19.8 3.1 0.88 8.7 0.0 4.7 5 0 0 5 5 5 1 TIP49 P-loop domain NB-ARC PF00931.22 KZN86366.1 - 0.00052 19.3 1.6 7.8 5.6 0.0 5.1 5 0 0 5 5 4 0 NB-ARC domain DAP3 PF10236.9 KZN86366.1 - 0.0018 17.5 1.9 0.5 9.5 0.0 4.1 4 0 0 4 4 4 1 Mitochondrial ribosomal death-associated protein 3 FeoB_N PF02421.18 KZN86366.1 - 0.0029 17.1 5.1 0.65 9.5 0.0 5.1 6 0 0 6 6 5 1 Ferrous iron transport protein B DnaB_C PF03796.15 KZN86366.1 - 0.0034 16.8 4.5 2.3 7.5 0.0 4.6 4 0 0 4 4 4 1 DnaB-like helicase C terminal domain CPT PF07931.12 KZN86366.1 - 0.0049 16.7 0.2 4 7.3 0.0 4.8 4 1 0 4 4 3 0 Chloramphenicol phosphotransferase-like protein ATPase PF06745.13 KZN86366.1 - 0.0062 15.9 0.5 29 3.9 0.0 4.5 5 0 0 5 5 4 0 KaiC MobB PF03205.14 KZN86366.1 - 0.0095 15.8 7.4 44 4.0 0.0 5.8 6 0 0 6 6 6 0 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.10 KZN86366.1 - 0.012 15.0 0.1 3.5 7.0 0.0 3.8 3 0 0 3 3 3 0 Chromatin associated protein KTI12 MeaB PF03308.16 KZN86366.1 - 0.032 13.2 1.4 4.7 6.1 0.2 3.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SUD-M PF11633.8 KZN86366.1 - 0.042 13.6 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Single-stranded poly(A) binding domain dNK PF01712.19 KZN86366.1 - 0.047 13.5 1.8 15 5.3 0.0 4.1 4 0 0 4 4 3 0 Deoxynucleoside kinase DEAD PF00270.29 KZN86366.1 - 0.066 13.0 0.3 19 5.0 0.0 3.7 4 0 0 4 4 3 0 DEAD/DEAH box helicase Septin PF00735.18 KZN86366.1 - 0.087 12.1 1.7 7.1 5.8 0.0 4.0 6 0 0 6 6 5 0 Septin TrwB_AAD_bind PF10412.9 KZN86366.1 - 0.35 9.7 2.5 14 4.5 0.1 3.7 4 0 0 4 4 4 0 Type IV secretion-system coupling protein DNA-binding domain Voltage_CLC PF00654.20 KZN86367.1 - 2.3e-89 300.1 22.4 2.3e-89 300.1 22.4 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KZN86367.1 - 0.00011 22.6 0.0 0.16 12.5 0.0 2.5 2 0 0 2 2 2 2 CBS domain CTK3 PF12243.8 KZN86368.1 - 1.3e-51 173.7 0.4 2.6e-51 172.8 0.2 1.5 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 KZN86368.1 - 4.3e-17 62.0 10.7 4.3e-17 62.0 10.7 1.9 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus DUF3873 PF12989.7 KZN86368.1 - 0.053 13.9 0.0 0.18 12.2 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) U3_snoRNA_assoc PF08297.11 KZN86369.1 - 4.3e-16 59.4 1.3 4.3e-16 59.4 1.3 3.8 3 1 0 3 3 3 1 U3 snoRNA associated DUF4355 PF14265.6 KZN86369.1 - 0.015 15.5 10.7 0.015 15.5 10.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Cwf_Cwc_15 PF04889.12 KZN86369.1 - 0.15 11.7 28.1 0.054 13.2 25.6 1.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF155 PF02582.14 KZN86370.1 - 2.7e-52 177.4 0.1 4.6e-52 176.7 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.6 KZN86370.1 - 0.054 14.0 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Mito_carr PF00153.27 KZN86372.1 - 2.8e-46 155.4 4.8 1.1e-15 57.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3716 PF12511.8 KZN86373.1 - 6.4e-12 45.3 10.1 9.7e-12 44.8 10.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Zn_clus PF00172.18 KZN86374.1 - 3.3e-08 33.5 7.2 6.3e-08 32.6 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KZN86374.1 - 4.1e-05 22.6 0.2 8.6e-05 21.5 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain WD40 PF00400.32 KZN86375.1 - 6e-38 128.2 24.5 2.5e-07 31.3 0.1 8.1 9 0 0 9 9 9 6 WD domain, G-beta repeat F-box-like PF12937.7 KZN86375.1 - 6.8e-11 41.9 0.4 1.4e-10 40.9 0.4 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KZN86375.1 - 1.5e-08 34.8 0.8 0.35 11.2 0.0 6.2 1 1 5 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KZN86375.1 - 4.4e-07 28.9 7.1 0.034 12.8 0.1 5.4 2 1 4 6 6 6 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KZN86375.1 - 8.2e-05 22.1 0.0 0.014 14.7 0.0 2.7 1 1 2 3 3 3 2 WD40-like domain F-box PF00646.33 KZN86375.1 - 0.00016 21.5 0.4 0.00042 20.1 0.4 1.8 1 0 0 1 1 1 1 F-box domain PALB2_WD40 PF16756.5 KZN86375.1 - 0.00066 18.7 3.4 0.7 8.8 0.0 3.9 2 1 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain F-box_5 PF18511.1 KZN86375.1 - 0.039 13.5 0.0 0.093 12.3 0.0 1.6 1 0 0 1 1 1 0 F-box PQQ_2 PF13360.6 KZN86375.1 - 0.055 13.0 4.4 0.24 11.0 1.4 3.0 1 1 1 2 2 2 0 PQQ-like domain zf_C2H2_ZHX PF18387.1 KZN86375.1 - 0.21 11.3 1.2 1.9 8.2 0.1 2.9 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Zip PF02535.22 KZN86376.1 - 8.2e-36 123.9 13.7 4.6e-25 88.5 5.9 2.9 1 1 1 2 2 2 2 ZIP Zinc transporter RTA1 PF04479.13 KZN86377.1 - 4.6e-54 183.2 3.7 4.6e-54 183.2 3.7 1.7 1 1 1 2 2 2 1 RTA1 like protein SUR7 PF06687.12 KZN86377.1 - 0.7 9.5 11.8 29 4.2 10.0 2.7 1 1 0 2 2 2 0 SUR7/PalI family Alginate_lyase PF05426.12 KZN86378.1 - 1.2e-15 57.8 1.3 2.9e-15 56.6 1.3 1.7 1 0 0 1 1 1 1 Alginate lyase Zn_clus PF00172.18 KZN86378.1 - 0.0031 17.6 1.5 0.0053 16.8 1.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hat1_N PF10394.9 KZN86379.1 - 5.4e-52 176.3 0.0 9.9e-52 175.4 0.0 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.7 KZN86379.1 - 0.19 11.7 0.0 0.59 10.1 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain LSM PF01423.22 KZN86380.1 - 6e-19 67.5 0.0 8.6e-19 67.0 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KZN86380.1 - 0.0032 17.6 0.0 0.0041 17.2 0.0 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain PPR_3 PF13812.6 KZN86381.1 - 1e-12 48.0 0.4 5.5e-05 23.2 0.0 5.9 4 2 3 7 7 7 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 KZN86381.1 - 3.5e-10 39.9 0.6 0.001 19.2 0.0 6.2 6 3 2 8 8 8 3 PPR repeat family PPR_long PF17177.4 KZN86381.1 - 2.3e-07 30.4 0.2 0.011 15.1 0.1 3.0 1 1 3 4 4 4 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KZN86381.1 - 3.8e-06 26.8 6.4 5.6 7.4 0.1 7.2 8 0 0 8 8 8 2 PPR repeat DUF1415 PF07209.12 KZN86381.1 - 0.06 13.1 0.0 0.19 11.5 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1415) DUF4355 PF14265.6 KZN86381.1 - 2.5 8.3 7.6 6.2 7.1 7.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DUF4837 PF16125.5 KZN86382.1 - 0.15 11.1 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4837) DSPc PF00782.20 KZN86383.1 - 5.7e-10 39.1 0.0 1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KZN86383.1 - 2.9e-06 27.0 0.0 4.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KZN86383.1 - 0.024 14.6 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KZN86383.1 - 0.082 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate PLA2_B PF01735.18 KZN86384.1 - 6.7e-27 94.0 0.0 2.7e-26 92.1 0.0 1.8 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Exo70 PF03081.15 KZN86385.1 - 5.5e-83 279.1 0.0 1.8e-82 277.4 0.0 1.7 2 0 0 2 2 2 1 Exo70 exocyst complex subunit NPV_P10 PF05531.12 KZN86385.1 - 0.096 13.2 2.8 5.6 7.5 0.0 4.1 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Lyase_1 PF00206.20 KZN86386.1 - 9.9e-22 77.7 0.0 2.3e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KZN86386.1 - 3e-16 59.7 0.4 1.1e-15 57.9 0.0 2.2 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus BCDHK_Adom3 PF10436.9 KZN86388.1 - 2.1e-74 248.8 0.0 2.8e-74 248.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KZN86388.1 - 8.4e-13 48.8 0.0 1.8e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KZN86388.1 - 0.063 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Crust_neurohorm PF01147.17 KZN86388.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family SKN1 PF03935.15 KZN86390.1 - 1.7e-220 732.7 0.1 1.9e-220 732.5 0.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) NuiA PF07924.11 KZN86391.1 - 0.0017 18.7 0.0 0.031 14.7 0.0 2.1 1 1 0 1 1 1 1 Nuclease A inhibitor-like protein Ribosomal_L3 PF00297.22 KZN86392.1 - 1.5e-184 613.2 11.8 1.7e-184 613.0 11.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 TPR_1 PF00515.28 KZN86393.1 - 2.3e-51 169.6 27.2 5.6e-08 32.3 0.1 10.9 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 KZN86393.1 - 2.1e-46 152.3 17.0 5.8e-06 26.0 0.0 10.7 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 KZN86393.1 - 1.6e-38 127.6 20.4 2.1e-06 27.5 0.0 10.8 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.6 KZN86393.1 - 8.6e-26 88.4 17.9 2.7e-05 24.2 0.1 9.7 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 KZN86393.1 - 8.7e-26 89.3 24.1 4.2e-05 23.1 1.5 9.8 6 3 3 9 9 9 7 TPR repeat TPR_12 PF13424.6 KZN86393.1 - 4.3e-24 84.6 15.8 5.2e-05 23.4 0.1 7.9 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 KZN86393.1 - 1.1e-23 83.5 17.0 0.00039 20.9 0.0 7.8 5 3 3 8 8 7 6 Tetratricopeptide repeat TPR_14 PF13428.6 KZN86393.1 - 1.5e-22 78.3 13.9 0.00035 21.1 0.0 9.1 6 3 4 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.6 KZN86393.1 - 1.5e-21 76.7 14.2 5.2e-05 23.8 0.1 8.1 5 2 3 8 8 8 5 Tetratricopeptide repeat TPR_6 PF13174.6 KZN86393.1 - 1e-18 66.6 15.0 0.0095 16.5 0.0 9.9 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 KZN86393.1 - 1.8e-18 65.1 12.2 0.031 14.3 0.0 9.6 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 KZN86393.1 - 2.7e-17 62.7 7.7 0.028 14.5 0.6 7.2 3 2 5 8 8 8 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KZN86393.1 - 3.6e-11 43.1 10.9 1.3e-07 31.7 1.4 4.0 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KZN86393.1 - 1.8e-08 33.9 8.0 0.00038 19.8 2.6 4.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_21 PF09976.9 KZN86393.1 - 4.9e-06 26.4 4.8 0.039 13.7 0.0 4.5 3 2 1 5 5 5 1 Tetratricopeptide repeat-like domain BTAD PF03704.17 KZN86393.1 - 6.7e-06 26.6 5.6 0.015 15.7 0.1 3.8 3 0 0 3 3 3 1 Bacterial transcriptional activator domain TPR_10 PF13374.6 KZN86393.1 - 0.0011 18.7 9.3 29 4.7 0.2 7.2 8 1 0 8 8 7 0 Tetratricopeptide repeat DUF2225 PF09986.9 KZN86393.1 - 0.0029 17.3 5.2 1.2 8.8 0.0 3.2 3 1 0 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_MalT PF17874.1 KZN86393.1 - 0.013 14.9 8.7 0.036 13.5 0.0 3.4 2 2 2 4 4 4 0 MalT-like TPR region TPR_20 PF14561.6 KZN86393.1 - 0.047 14.0 1.1 9.5 6.6 0.1 3.9 2 1 2 4 4 4 0 Tetratricopeptide repeat Syntaxin-6_N PF09177.11 KZN86393.1 - 0.17 12.5 0.5 1.5 9.4 0.2 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal RPN6_N PF18055.1 KZN86393.1 - 0.2 12.0 1.5 0.9 9.9 0.3 2.5 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain ChAPs PF09295.10 KZN86393.1 - 0.28 10.1 2.4 6.8 5.6 0.2 2.7 2 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) GFO_IDH_MocA PF01408.22 KZN86395.1 - 1.3e-17 64.7 0.0 2.3e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KZN86395.1 - 3.4e-17 62.5 0.1 7.8e-17 61.4 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain MFS_1 PF07690.16 KZN86396.1 - 4.3e-35 121.3 28.3 4.3e-35 121.3 28.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily RNase_T PF00929.24 KZN86397.1 - 9.7e-07 29.5 0.0 1.6e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Exonuclease zf-C2H2_4 PF13894.6 KZN86397.1 - 0.00023 21.7 0.4 0.49 11.4 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KZN86397.1 - 0.00036 20.7 0.2 0.94 9.8 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding DNA_pol_A_exo1 PF01612.20 KZN86397.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 3'-5' exonuclease zf-met PF12874.7 KZN86397.1 - 0.027 14.9 0.7 11 6.5 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KZN86397.1 - 0.037 14.3 0.1 0.15 12.4 0.0 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KZN86397.1 - 0.28 11.7 1.0 9 7.0 0.1 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type p450 PF00067.22 KZN86398.1 - 1.3e-66 225.3 0.0 1.5e-66 225.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TRI5 PF06330.11 KZN86400.1 - 1.3e-35 122.9 0.5 1.5e-35 122.7 0.5 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) YxiJ PF14176.6 KZN86400.1 - 0.0043 17.5 0.1 0.0082 16.6 0.1 1.5 1 0 0 1 1 1 1 YxiJ-like protein Chromo PF00385.24 KZN86401.1 - 7.6e-07 29.0 0.0 1.6e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Fructosamin_kin PF03881.14 KZN86402.1 - 2.4e-39 135.3 0.0 3.2e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KZN86402.1 - 1.1e-05 25.5 0.0 1.7e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Glyco_hydro_16 PF00722.21 KZN86403.1 - 6.1e-08 32.3 0.2 1.2e-07 31.4 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Ala_racemase_N PF01168.20 KZN86404.1 - 4.3e-28 98.5 0.1 5.2e-28 98.2 0.1 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 KZN86404.1 - 2e-20 73.2 0.0 5e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 Putative serine dehydratase domain SDH_alpha PF03313.15 KZN86404.1 - 0.025 14.3 0.3 0.65 9.6 0.1 2.2 2 0 0 2 2 2 0 Serine dehydratase alpha chain GTP_CH_N PF12471.8 KZN86404.1 - 0.093 12.5 0.0 0.81 9.4 0.0 2.2 3 0 0 3 3 3 0 GTP cyclohydrolase N terminal 2OG-FeII_Oxy_2 PF13532.6 KZN86405.1 - 1.6e-15 57.8 0.0 2e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KZN86405.1 - 0.0018 18.8 0.0 0.0041 17.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_12 PF13424.6 KZN86406.1 - 5.8e-24 84.2 8.5 1.2e-07 31.9 0.0 5.4 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 KZN86406.1 - 3.2e-16 58.6 2.7 0.0046 16.8 0.0 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat NB-ARC PF00931.22 KZN86406.1 - 1.6e-15 57.0 0.0 3.4e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_MalT PF17874.1 KZN86406.1 - 1.5e-08 34.4 0.4 4.6e-05 22.9 0.5 2.5 1 1 1 2 2 2 2 MalT-like TPR region TPR_2 PF07719.17 KZN86406.1 - 1.7e-08 33.9 12.9 1.3 9.3 0.0 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KZN86406.1 - 2.5e-08 33.5 5.7 2.1 8.8 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KZN86406.1 - 2.4e-06 27.1 2.7 0.86 9.5 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat AAA_16 PF13191.6 KZN86406.1 - 2.8e-06 27.8 0.2 2.7e-05 24.6 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain TPR_7 PF13176.6 KZN86406.1 - 1.5e-05 24.6 2.8 2.4 8.4 0.0 5.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KZN86406.1 - 0.0026 18.4 5.3 3.4 8.7 0.0 5.5 5 1 1 6 6 6 1 Tetratricopeptide repeat AAA_22 PF13401.6 KZN86406.1 - 0.011 16.0 0.0 0.15 12.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain TPR_16 PF13432.6 KZN86406.1 - 0.015 16.0 4.0 52 4.6 0.0 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 KZN86406.1 - 0.03 14.9 0.1 7.3 7.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KZN86406.1 - 0.031 14.8 3.6 0.62 10.6 0.0 4.0 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KZN86406.1 - 0.13 12.9 1.1 19 6.2 0.0 4.6 6 0 0 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KZN86406.1 - 0.9 9.8 3.4 3.9 7.8 0.0 3.3 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3295 PF11702.8 KZN86407.1 - 0.72 9.1 11.3 0.91 8.8 11.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) FAM53 PF15242.6 KZN86407.1 - 2.5 7.9 13.2 3.2 7.5 13.2 1.1 1 0 0 1 1 1 0 Family of FAM53 Podoplanin PF05808.11 KZN86408.1 - 0.00014 22.0 0.2 0.00022 21.4 0.2 1.3 1 0 0 1 1 1 1 Podoplanin VSP PF03302.13 KZN86408.1 - 0.0049 15.8 0.5 0.0063 15.4 0.5 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF2207 PF09972.9 KZN86408.1 - 0.01 14.6 0.0 0.022 13.5 0.0 1.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Mid2 PF04478.12 KZN86408.1 - 0.066 13.0 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Amnionless PF14828.6 KZN86408.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Amnionless RdRP_5 PF07925.11 KZN86408.1 - 1.3 6.4 4.0 1.7 6.0 4.0 1.0 1 0 0 1 1 1 0 Reovirus RNA-dependent RNA polymerase lambda 3 Glyco_transf_28 PF03033.20 KZN86409.1 - 3.9e-22 78.8 0.0 8.1e-22 77.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain ATG_C PF09333.11 KZN86409.1 - 0.00057 20.2 0.0 0.0024 18.2 0.0 2.0 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain UDPGT PF00201.18 KZN86409.1 - 0.092 11.5 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase VPS13_C PF16909.5 KZN86409.1 - 0.2 11.4 0.1 0.41 10.4 0.1 1.5 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal Transferase PF02458.15 KZN86410.1 - 2e-32 112.4 0.0 2.8e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Transferase family Condensation PF00668.20 KZN86410.1 - 0.00035 19.4 0.0 0.00053 18.8 0.0 1.2 1 0 0 1 1 1 1 Condensation domain p450 PF00067.22 KZN86411.1 - 4.6e-69 233.3 0.0 6.2e-69 232.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KZN86412.1 - 1.9e-17 63.3 48.2 5.5e-11 42.0 34.5 3.3 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KZN86412.1 - 1.5e-14 53.3 12.8 2.2e-14 52.8 12.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) NAD_binding_10 PF13460.6 KZN86414.1 - 2.6e-12 47.0 0.6 5.1e-12 46.1 0.6 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KZN86414.1 - 2.7e-10 40.1 0.1 4.4e-09 36.2 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KZN86414.1 - 2.9e-08 33.6 0.4 4.4e-08 33.0 0.4 1.3 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KZN86414.1 - 2.4e-07 31.2 0.1 4.6e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KZN86414.1 - 0.00012 21.4 0.0 0.00029 20.1 0.1 1.7 1 1 1 2 2 2 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 KZN86414.1 - 0.00046 20.4 0.1 0.00071 19.8 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 KZN86414.1 - 0.0011 18.2 0.2 0.0075 15.4 0.3 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KZN86414.1 - 0.0011 18.1 0.3 0.002 17.3 0.3 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KZN86414.1 - 0.0035 16.4 0.1 0.0074 15.3 0.1 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DXP_reductoisom PF02670.16 KZN86414.1 - 0.0044 17.7 0.1 0.0078 16.9 0.1 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.20 KZN86414.1 - 0.023 14.8 0.0 0.075 13.2 0.1 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus GDP_Man_Dehyd PF16363.5 KZN86414.1 - 0.036 13.5 0.0 2.9 7.2 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase GFO_IDH_MocA PF01408.22 KZN86414.1 - 0.073 13.9 0.2 0.17 12.7 0.1 1.6 2 0 0 2 2 1 0 Oxidoreductase family, NAD-binding Rossmann fold NUC173 PF08161.12 KZN86415.1 - 1.4e-80 269.8 0.0 1.8e-77 259.6 0.0 3.1 3 0 0 3 3 3 2 NUC173 domain CdiI_2 PF18593.1 KZN86415.1 - 0.011 16.3 0.0 4.8 7.9 0.0 3.3 3 0 0 3 3 3 0 CdiI immunity protein DUF3384 PF11864.8 KZN86415.1 - 0.013 14.4 1.4 33 3.2 0.0 4.4 4 1 1 5 5 5 0 Domain of unknown function (DUF3384) HEAT PF02985.22 KZN86415.1 - 0.072 13.4 1.9 16 6.1 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat DUF5071 PF16804.5 KZN86415.1 - 0.08 13.2 0.0 25 5.2 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5071) HrpB1_HrpK PF09613.10 KZN86415.1 - 0.12 12.1 0.1 3 7.5 0.0 3.1 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TFCD_C PF12612.8 KZN86415.1 - 0.14 12.0 0.7 12 5.7 0.0 3.7 4 0 0 4 4 4 0 Tubulin folding cofactor D C terminal DUF3385 PF11865.8 KZN86415.1 - 0.14 12.0 0.0 18 5.2 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) Striatin PF08232.12 KZN86415.1 - 0.21 12.2 2.3 14 6.2 1.0 2.6 2 0 0 2 2 2 0 Striatin family LSM PF01423.22 KZN86416.1 - 2.9e-14 52.5 0.0 4.7e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 LSM domain DNA_pol3_chi PF04364.13 KZN86416.1 - 0.068 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC zf-C2H2 PF00096.26 KZN86417.1 - 5.8e-08 32.8 17.1 0.00077 19.8 4.5 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KZN86417.1 - 5.8e-07 29.7 22.6 5.8e-05 23.3 3.3 4.5 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KZN86417.1 - 0.0021 18.7 15.8 0.054 14.4 3.0 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KZN86417.1 - 0.038 14.3 1.4 0.12 12.7 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KZN86417.1 - 0.048 14.3 2.1 0.15 12.7 0.2 2.7 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KZN86417.1 - 0.14 12.2 0.8 9.1 6.4 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger SAP30_Sin3_bdg PF13867.6 KZN86418.1 - 3.5e-09 36.8 0.0 7.1e-08 32.7 0.0 2.4 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Dysbindin PF04440.16 KZN86418.1 - 0.093 12.9 0.3 0.093 12.9 0.3 2.1 3 0 0 3 3 3 0 Dysbindin (Dystrobrevin binding protein 1) BRO1 PF03097.18 KZN86419.1 - 8.7e-122 406.7 2.7 2.1e-121 405.4 2.7 1.7 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KZN86419.1 - 4.6e-69 233.0 15.9 4.6e-69 233.0 15.9 2.1 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV GST_C_3 PF14497.6 KZN86419.1 - 0.064 13.5 0.2 0.26 11.5 0.2 2.1 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HSBP1 PF06825.12 KZN86419.1 - 0.15 12.0 0.8 21 5.1 0.3 2.6 2 0 0 2 2 2 0 Heat shock factor binding protein 1 BLOC1_2 PF10046.9 KZN86419.1 - 0.92 9.8 9.9 6.9 7.1 0.1 5.1 3 1 3 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DnaJ_C PF01556.18 KZN86420.1 - 2e-35 122.0 0.0 2.8e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KZN86420.1 - 1.5e-22 79.5 3.4 2.5e-22 78.7 3.4 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KZN86420.1 - 4.2e-09 36.6 18.6 1e-08 35.4 18.6 1.7 1 0 0 1 1 1 1 DnaJ central domain GRP PF07172.11 KZN86420.1 - 1.1 10.0 15.4 5.1 7.9 15.4 2.2 1 0 0 1 1 1 0 Glycine rich protein family Anti-TRAP PF15777.5 KZN86420.1 - 2.1 8.4 16.3 0.28 11.2 2.4 2.9 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KZN86420.1 - 5.6 7.0 7.1 13 5.8 6.0 2.0 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lon_C PF05362.13 KZN86421.1 - 3.5e-64 216.1 0.0 6.6e-64 215.2 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KZN86421.1 - 4.4e-32 111.6 0.0 9.2e-32 110.6 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KZN86421.1 - 9.1e-22 77.9 0.0 1.9e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KZN86421.1 - 2.3e-07 30.9 0.0 4.4e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 KZN86421.1 - 2.6e-06 27.3 0.1 9.7e-06 25.4 0.0 2.0 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 KZN86421.1 - 5.9e-06 26.5 0.0 1.5e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 KZN86421.1 - 7e-06 25.2 0.2 1.6e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain AAA_22 PF13401.6 KZN86421.1 - 1e-05 25.8 0.1 0.00012 22.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KZN86421.1 - 8.2e-05 23.0 0.1 0.00073 19.9 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KZN86421.1 - 0.00017 21.4 0.0 0.00056 19.7 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KZN86421.1 - 0.0034 17.9 0.7 0.027 15.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 KZN86421.1 - 0.0059 16.6 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KZN86421.1 - 0.021 14.6 0.0 0.057 13.2 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein DNTTIP1_dimer PF18192.1 KZN86421.1 - 0.022 15.1 0.7 3 8.3 0.1 3.0 2 1 0 2 2 2 0 DNTTIP1 dimerisation domain AAA_30 PF13604.6 KZN86421.1 - 0.024 14.4 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KZN86421.1 - 0.05 12.8 0.0 0.56 9.4 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 KZN86421.1 - 0.06 13.3 0.2 0.56 10.1 0.0 2.4 1 1 1 2 2 2 0 NTPase RNA_helicase PF00910.22 KZN86421.1 - 0.064 13.6 0.0 0.21 12.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase DUF4276 PF14103.6 KZN86421.1 - 0.072 13.3 0.3 0.18 12.0 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4276) RsgA_GTPase PF03193.16 KZN86421.1 - 0.088 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 KZN86421.1 - 0.16 11.5 0.5 0.33 10.4 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 KZN86421.1 - 0.17 12.4 1.7 0.41 11.2 0.1 2.2 2 0 0 2 2 2 0 ABC transporter F-box-like_2 PF13013.6 KZN86421.1 - 0.19 11.7 0.0 0.48 10.4 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain Pkinase_Tyr PF07714.17 KZN86422.1 - 3.9e-09 36.2 0.0 3.2e-08 33.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KZN86422.1 - 7.6e-09 35.3 0.0 8.8e-08 31.8 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain NumbF PF06311.12 KZN86422.1 - 9.1 6.9 9.3 11 6.7 1.1 3.9 3 0 0 3 3 3 0 NUMB domain cobW PF02492.19 KZN86423.1 - 3e-29 101.9 0.1 3.9e-29 101.5 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KZN86423.1 - 0.00023 21.0 0.0 0.00045 20.1 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 KZN86423.1 - 0.094 12.6 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase Mob1_phocein PF03637.17 KZN86424.1 - 2.7e-21 76.3 0.2 4.8e-21 75.5 0.2 1.3 1 0 0 1 1 1 1 Mob1/phocein family Bap31_Bap29_C PF18035.1 KZN86424.1 - 0.021 14.8 12.6 0.32 11.0 0.2 3.5 1 1 1 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Nup88 PF10168.9 KZN86424.1 - 0.025 12.4 2.6 0.037 11.9 2.6 1.1 1 0 0 1 1 1 0 Nuclear pore component ORF11CD3 PF10549.9 KZN86424.1 - 0.046 13.8 2.4 4 7.6 0.2 2.5 2 0 0 2 2 2 0 ORF11CD3 domain HJURP_C PF12347.8 KZN86424.1 - 0.081 13.0 7.4 0.11 12.5 1.5 3.2 1 1 1 2 2 2 0 Holliday junction regulator protein family C-terminal repeat MPS2 PF17060.5 KZN86424.1 - 0.23 10.7 2.6 0.41 9.9 2.6 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 60KD_IMP PF02096.20 KZN86424.1 - 0.28 11.1 2.5 0.5 10.3 2.5 1.4 1 0 0 1 1 1 0 60Kd inner membrane protein ATP-synt_D PF01813.17 KZN86424.1 - 0.46 10.3 5.1 0.15 11.9 1.9 1.8 2 1 0 2 2 2 0 ATP synthase subunit D HALZ PF02183.18 KZN86424.1 - 0.65 10.3 7.3 2.2 8.5 0.6 3.1 2 1 1 3 3 3 0 Homeobox associated leucine zipper DUF4407 PF14362.6 KZN86424.1 - 2 7.7 5.0 0.35 10.2 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HIT PF01230.23 KZN86425.1 - 7.3e-25 87.6 0.4 1.7e-24 86.4 0.1 1.6 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 KZN86425.1 - 2.8e-05 24.6 0.0 4.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GalP_UDP_tr_C PF02744.17 KZN86425.1 - 0.067 12.9 0.0 0.093 12.4 0.0 1.2 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain HD_3 PF13023.6 KZN86426.1 - 9.7e-49 165.5 0.2 1.2e-48 165.2 0.2 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KZN86426.1 - 5.1e-13 49.2 0.2 6.5e-13 48.8 0.2 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 KZN86426.1 - 0.041 14.1 0.5 0.099 12.9 0.5 1.7 1 1 0 1 1 1 0 HD domain HAUS6_N PF14661.6 KZN86427.1 - 3.3e-41 141.3 0.1 5e-41 140.8 0.1 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus Ank_2 PF12796.7 KZN86428.1 - 7.2e-42 141.9 2.4 1e-12 48.5 0.1 5.5 2 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN86428.1 - 8.3e-32 109.2 1.2 8.2e-09 35.8 0.2 8.4 3 2 7 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN86428.1 - 3.2e-25 85.4 0.8 0.015 15.7 0.0 10.7 11 0 0 11 11 11 4 Ankyrin repeat Ank_5 PF13857.6 KZN86428.1 - 4e-24 84.4 7.4 0.00094 19.4 0.1 9.4 2 2 8 10 10 10 7 Ankyrin repeats (many copies) Ank PF00023.30 KZN86428.1 - 1.8e-13 50.3 10.3 1.2 9.7 0.0 10.7 11 0 0 11 11 11 2 Ankyrin repeat NACHT PF05729.12 KZN86428.1 - 1.3e-07 31.6 0.6 3.5e-07 30.3 0.5 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KZN86428.1 - 3.5e-05 24.3 0.1 0.00011 22.6 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KZN86428.1 - 0.0035 17.6 0.0 0.025 14.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 KZN86428.1 - 0.0057 17.1 0.0 0.97 9.9 0.0 2.9 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KZN86428.1 - 0.0097 16.4 0.0 0.036 14.6 0.0 2.0 2 0 0 2 2 1 1 ABC transporter AAA_18 PF13238.6 KZN86428.1 - 0.01 16.4 0.3 0.14 12.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KZN86428.1 - 0.056 13.8 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 KZN86428.1 - 0.077 13.2 0.0 0.28 11.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain ADK PF00406.22 KZN86428.1 - 0.37 10.9 2.6 13 5.9 0.0 3.3 3 0 0 3 3 3 0 Adenylate kinase NACHT_sigma PF17106.5 KZN86428.1 - 1.5 9.1 13.1 3.8 7.7 13.1 1.7 1 0 0 1 1 1 0 Sigma domain on NACHT-NTPases HicA_toxin PF07927.12 KZN86428.1 - 2 8.5 3.9 44 4.2 0.0 4.6 5 0 0 5 5 5 0 HicA toxin of bacterial toxin-antitoxin, YajC PF02699.15 KZN86428.1 - 4.4 7.3 7.7 13 5.8 0.1 4.7 2 2 4 6 6 6 0 Preprotein translocase subunit DUF676 PF05057.14 KZN86429.1 - 5.7e-05 22.7 0.0 0.00013 21.5 0.0 1.6 2 0 0 2 2 2 1 Putative serine esterase (DUF676) NACHT_sigma PF17106.5 KZN86429.1 - 0.0015 18.7 7.7 0.0041 17.2 7.7 1.8 1 0 0 1 1 1 1 Sigma domain on NACHT-NTPases Spt4 PF06093.13 KZN86429.1 - 0.017 15.2 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger Abhydrolase_8 PF06259.12 KZN86429.1 - 0.023 14.3 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase PGAP1 PF07819.13 KZN86429.1 - 0.025 14.3 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 KZN86429.1 - 0.085 13.5 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_9 PF10081.9 KZN86429.1 - 0.098 11.7 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family NACHT_sigma PF17106.5 KZN86430.1 - 5.6e-07 29.6 16.9 9.5e-07 28.9 16.9 1.4 1 0 0 1 1 1 1 Sigma domain on NACHT-NTPases SesA PF17107.5 KZN86430.1 - 0.001 19.2 0.0 0.0018 18.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Neur_chan_memb PF02932.16 KZN86432.1 - 0.12 12.4 0.1 0.21 11.6 0.0 1.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF4175 PF13779.6 KZN86432.1 - 7.8 4.3 14.1 13 3.5 14.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CoA_binding_2 PF13380.6 KZN86433.1 - 9.1e-28 97.1 0.0 1.1e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain Rad4 PF03835.15 KZN86434.1 - 1.1e-35 122.5 0.0 2.8e-35 121.2 0.0 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KZN86434.1 - 1e-28 99.5 0.1 2.2e-28 98.5 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KZN86434.1 - 2.3e-14 52.9 0.0 5.1e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KZN86434.1 - 8.3e-13 49.1 0.4 8.3e-13 49.1 0.4 3.7 4 0 0 4 4 4 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KZN86434.1 - 0.00094 19.6 0.0 0.0026 18.2 0.0 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily Colicin_Pyocin PF01320.18 KZN86434.1 - 0.053 13.6 0.1 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein Dioxygenase_C PF00775.21 KZN86435.1 - 5.1e-06 26.1 0.8 1.3e-05 24.8 0.1 2.0 2 1 0 2 2 2 1 Dioxygenase Sugar_tr PF00083.24 KZN86436.1 - 1.3e-132 442.9 27.1 1.5e-132 442.7 27.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN86436.1 - 5.5e-29 101.2 50.1 1.3e-24 86.9 30.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KZN86436.1 - 0.0055 15.2 9.9 0.0098 14.4 4.1 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF1689 PF07954.11 KZN86436.1 - 0.12 12.8 0.1 6 7.3 0.0 3.0 2 2 1 3 3 3 0 Protein of unknown function (DUF1689) Cytochrom_B_C PF00032.17 KZN86436.1 - 1 9.7 5.9 2.9 8.2 2.9 2.6 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD Ank_2 PF12796.7 KZN86437.1 - 3e-42 143.1 0.2 1.5e-11 44.7 0.3 5.1 1 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KZN86437.1 - 5.8e-33 109.2 5.0 0.0012 19.2 0.0 10.4 10 2 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.6 KZN86437.1 - 5e-31 106.7 6.2 1.9e-06 28.3 0.0 7.1 4 2 3 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 KZN86437.1 - 3.3e-30 103.2 8.3 0.00027 21.3 0.1 9.4 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 KZN86437.1 - 1.2e-22 79.6 5.5 0.00025 21.3 0.2 8.5 5 2 4 9 9 9 7 Ankyrin repeats (many copies) LPMO_10 PF03067.15 KZN86440.1 - 9.9e-13 49.2 2.4 1.9e-12 48.2 2.4 1.5 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading AA_permease_2 PF13520.6 KZN86441.1 - 4.2e-48 164.2 49.7 5.4e-48 163.9 49.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN86441.1 - 3.1e-09 36.0 47.9 8e-09 34.6 47.9 1.6 1 1 0 1 1 1 1 Amino acid permease TraH PF06122.11 KZN86441.1 - 0.23 10.7 0.4 0.36 10.1 0.4 1.2 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein adh_short_C2 PF13561.6 KZN86443.1 - 8.5e-60 202.2 0.1 9.8e-60 202.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN86443.1 - 6e-40 136.8 0.1 7.2e-40 136.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN86443.1 - 1.5e-08 34.8 0.4 2.3e-08 34.2 0.4 1.3 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KZN86443.1 - 0.0024 17.8 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KZN86443.1 - 0.0069 17.1 0.0 0.012 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain THF_DHG_CYH_C PF02882.19 KZN86443.1 - 0.011 15.1 0.2 0.032 13.6 0.1 1.8 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.15 KZN86443.1 - 0.037 13.2 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RecC_C PF17946.1 KZN86443.1 - 0.051 13.3 0.0 0.077 12.8 0.0 1.2 1 0 0 1 1 1 0 RecC C-terminal domain Epimerase PF01370.21 KZN86443.1 - 0.065 12.7 0.0 0.09 12.2 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Gln-synt_C PF00120.24 KZN86444.1 - 1.2e-81 274.5 0.0 1.4e-81 274.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Malate_synthase PF01274.22 KZN86445.1 - 1.5e-230 766.0 0.0 1.7e-230 765.8 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Glyco_hydro_3_C PF01915.22 KZN86447.1 - 4.9e-44 150.7 0.0 7.6e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KZN86447.1 - 3.6e-34 118.6 0.0 5.5e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KZN86447.1 - 1e-22 80.0 0.2 2.1e-22 79.0 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain ABC_tran PF00005.27 KZN86448.1 - 3.6e-47 160.3 0.0 2.1e-25 89.8 0.0 4.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KZN86448.1 - 1.2e-15 58.2 3.3 1.1e-05 25.4 0.0 4.2 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KZN86448.1 - 3.1e-11 43.1 0.9 0.0026 17.2 0.0 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KZN86448.1 - 2.8e-07 31.2 0.1 0.014 15.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KZN86448.1 - 2.3e-06 27.7 0.0 0.049 13.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Chromo PF00385.24 KZN86448.1 - 3.6e-06 26.8 0.0 7e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.6 KZN86448.1 - 6.4e-06 25.8 1.5 0.063 13.0 0.5 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KZN86448.1 - 4.5e-05 23.4 0.1 0.41 10.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 KZN86448.1 - 0.0003 21.0 1.6 0.28 11.2 0.4 3.3 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_28 PF13521.6 KZN86448.1 - 0.00035 20.9 0.0 0.19 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KZN86448.1 - 0.00041 20.2 0.3 0.52 9.9 0.4 2.4 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 KZN86448.1 - 0.0012 18.8 0.1 0.25 11.2 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KZN86448.1 - 0.0019 18.5 0.1 0.4 11.0 0.0 3.2 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KZN86448.1 - 0.0026 17.9 0.0 1.3 9.3 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MeaB PF03308.16 KZN86448.1 - 0.0028 16.7 0.1 0.97 8.4 0.1 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 KZN86448.1 - 0.0054 16.8 0.0 0.52 10.3 0.0 3.0 3 0 0 3 3 3 1 Dynamin family RNA_helicase PF00910.22 KZN86448.1 - 0.0074 16.7 0.1 1.8 9.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 KZN86448.1 - 0.0081 16.3 0.1 3.2 7.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 KZN86448.1 - 0.012 15.3 0.3 1.3 8.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain DNA_ligase_OB_2 PF14743.6 KZN86448.1 - 0.014 15.4 0.3 0.037 14.0 0.3 1.7 1 0 0 1 1 1 0 DNA ligase OB-like domain AAA_30 PF13604.6 KZN86448.1 - 0.015 15.1 0.2 7.2 6.3 0.1 2.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KZN86448.1 - 0.02 15.3 0.0 0.89 10.0 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CLASP_N PF12348.8 KZN86448.1 - 0.022 14.3 0.0 0.93 9.0 0.2 2.4 2 0 0 2 2 2 0 CLASP N terminal AAA_18 PF13238.6 KZN86448.1 - 0.024 15.2 0.0 7.2 7.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KZN86448.1 - 0.028 13.6 0.1 3.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 KZN86448.1 - 0.033 13.9 0.0 7.4 6.3 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation HEAT PF02985.22 KZN86448.1 - 0.037 14.3 0.5 17 6.0 0.1 4.3 4 0 0 4 4 4 0 HEAT repeat AAA_14 PF13173.6 KZN86448.1 - 0.05 13.6 0.0 1.6 8.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 KZN86448.1 - 0.075 11.7 0.0 3.2 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KZN86448.1 - 0.087 12.1 0.1 11 5.2 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.22 KZN86448.1 - 0.093 11.9 1.2 0.3 10.3 0.0 2.3 3 0 0 3 3 3 0 NB-ARC domain Septin PF00735.18 KZN86448.1 - 0.11 11.7 0.0 15 4.7 0.0 2.2 2 0 0 2 2 2 0 Septin TsaE PF02367.17 KZN86448.1 - 0.12 12.4 0.3 21 5.1 0.0 2.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 KZN86448.1 - 0.17 12.1 0.0 32 4.8 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MukB PF04310.12 KZN86448.1 - 0.2 11.4 0.4 24 4.7 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal ALF PF03752.13 KZN86448.1 - 0.22 11.5 6.9 2.4 8.2 0.2 3.6 3 0 0 3 3 3 0 Short repeats of unknown function CLP1_P PF16575.5 KZN86448.1 - 0.23 11.2 2.4 17 5.1 0.0 3.2 4 0 0 4 4 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop HEAT_EZ PF13513.6 KZN86448.1 - 0.27 11.8 0.7 3.8 8.1 0.1 3.1 3 0 0 3 3 2 0 HEAT-like repeat AAA_27 PF13514.6 KZN86448.1 - 0.59 9.7 2.6 11 5.5 0.0 2.6 3 0 0 3 3 2 0 AAA domain Citrate_synt PF00285.21 KZN86449.1 - 1.3e-96 323.9 0.0 1.5e-96 323.6 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain AMP-binding PF00501.28 KZN86450.1 - 1.9e-72 244.2 0.0 2.4e-72 243.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KZN86450.1 - 1.6e-06 29.0 0.0 8.3e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain BATS PF06968.13 KZN86451.1 - 1.6e-22 79.4 0.2 7.2e-22 77.3 0.0 2.1 2 1 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KZN86451.1 - 1.1e-16 61.6 0.0 2.2e-15 57.4 0.1 2.2 2 0 0 2 2 2 1 Radical SAM superfamily FAD_binding_4 PF01565.23 KZN86453.1 - 4.7e-23 81.5 1.4 1.8e-22 79.6 1.4 2.1 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KZN86453.1 - 6.2e-12 45.4 0.4 1.6e-11 44.1 0.4 1.7 1 0 0 1 1 1 1 Berberine and berberine like Aa_trans PF01490.18 KZN86454.1 - 5.8e-38 130.7 31.1 7.7e-38 130.3 31.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Neurensin PF14927.6 KZN86454.1 - 0.4 10.4 3.6 0.28 10.9 1.1 2.1 2 0 0 2 2 2 0 Neurensin Aminotran_3 PF00202.21 KZN86455.1 - 7.5e-37 126.9 0.0 5.5e-15 54.9 0.0 3.1 3 0 0 3 3 3 3 Aminotransferase class-III AAA_26 PF13500.6 KZN86455.1 - 1.1e-22 80.9 0.0 2.8e-22 79.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain Aminotran_1_2 PF00155.21 KZN86456.1 - 5.6e-35 121.2 0.0 6.8e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 KZN86456.1 - 0.0006 18.7 0.0 0.00094 18.0 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.19 KZN86456.1 - 0.011 14.7 0.0 0.73 8.7 0.0 2.2 2 0 0 2 2 2 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KZN86456.1 - 0.098 11.2 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme E1-E2_ATPase PF00122.20 KZN86457.1 - 6.6e-38 130.0 16.9 9e-31 106.8 0.1 3.9 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KZN86457.1 - 3.7e-26 91.9 8.0 3.7e-26 91.9 8.0 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 KZN86457.1 - 8.2e-19 67.1 0.0 1.7e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KZN86457.1 - 1.8e-18 67.6 0.1 3.7e-17 63.3 0.1 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KZN86457.1 - 5.1e-15 55.3 0.0 1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) DctM PF06808.12 KZN86457.1 - 3.9e-05 22.6 6.6 0.00057 18.8 0.3 2.9 3 0 0 3 3 3 2 Tripartite ATP-independent periplasmic transporter, DctM component Hydrolase_3 PF08282.12 KZN86457.1 - 0.00096 19.0 0.2 0.011 15.5 0.3 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 KZN86457.1 - 0.069 13.0 0.4 0.15 11.9 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) zf-rbx1 PF12678.7 KZN86458.1 - 1.2e-09 38.3 9.0 5e-09 36.3 3.8 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KZN86458.1 - 2.6e-08 34.0 10.3 1.6e-06 28.3 4.0 2.6 2 0 0 2 2 2 2 Ring finger domain zf-ANAPC11 PF12861.7 KZN86458.1 - 2.8e-07 30.5 1.5 2.8e-07 30.5 1.5 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KZN86458.1 - 1.6e-06 27.9 6.8 1.1e-05 25.2 1.2 2.8 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KZN86458.1 - 9e-06 25.3 3.7 0.0018 17.9 0.1 3.3 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4 PF00097.25 KZN86458.1 - 1.7e-05 24.6 2.6 1.7e-05 24.6 2.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KZN86458.1 - 0.00013 21.9 8.1 0.00016 21.6 2.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KZN86458.1 - 0.00046 20.0 10.4 0.00055 19.8 1.9 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KZN86458.1 - 0.00062 19.7 9.6 0.015 15.3 6.3 3.2 1 1 1 2 2 2 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KZN86458.1 - 0.00076 19.1 2.8 0.00076 19.1 2.8 1.9 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 KZN86458.1 - 0.0016 18.3 1.8 0.0016 18.3 1.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 KZN86458.1 - 0.02 14.8 5.8 0.04 13.8 3.1 2.4 2 1 0 2 2 2 0 PHD-finger RINGv PF12906.7 KZN86458.1 - 0.024 14.8 0.5 0.024 14.8 0.5 2.5 2 1 1 3 3 3 0 RING-variant domain zf-C2H2_4 PF13894.6 KZN86458.1 - 0.092 13.6 1.5 2.5 9.2 0.2 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger Phage_holin_2_4 PF16082.5 KZN86458.1 - 0.16 11.7 0.1 0.31 10.8 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like FANCL_C PF11793.8 KZN86458.1 - 0.34 11.1 11.7 3.8 7.7 6.7 3.1 2 1 0 2 2 2 0 FANCL C-terminal domain GAGA PF09237.11 KZN86458.1 - 0.39 10.6 3.0 15 5.5 0.1 2.4 2 0 0 2 2 2 0 GAGA factor zf-C3HC4_4 PF15227.6 KZN86458.1 - 1.1 9.5 10.6 1 9.5 1.2 2.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KZN86458.1 - 1.2 9.0 9.7 0.087 12.6 2.6 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn-C2H2_12 PF18112.1 KZN86458.1 - 4.3 7.9 10.7 0.88 10.1 0.8 3.1 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain dCMP_cyt_deam_1 PF00383.23 KZN86459.1 - 3.1e-05 23.8 0.0 4.2e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF4567 PF15131.6 KZN86459.1 - 0.031 14.3 0.2 0.048 13.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4567) MOFRL PF05161.13 KZN86459.1 - 0.1 12.8 0.2 0.24 11.6 0.1 1.5 1 1 0 1 1 1 0 MOFRL family Pectinesterase PF01095.19 KZN86460.1 - 1.2e-53 181.8 4.9 1.6e-53 181.4 4.9 1.0 1 0 0 1 1 1 1 Pectinesterase Pectate_lyase_3 PF12708.7 KZN86460.1 - 0.00075 19.4 6.0 0.0011 18.8 6.0 1.2 1 0 0 1 1 1 1 Pectate lyase superfamily protein DUF4402 PF14352.6 KZN86460.1 - 0.01 16.4 2.8 0.028 15.1 2.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4402) Glyco_hydro_28 PF00295.17 KZN86461.1 - 1e-57 195.7 13.0 1.4e-57 195.3 13.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KZN86461.1 - 0.011 15.6 8.6 0.033 14.0 8.6 1.9 1 1 0 1 1 1 0 Right handed beta helix region MmgE_PrpD PF03972.14 KZN86462.1 - 7.6e-147 489.4 0.0 8.8e-147 489.2 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DUF1266 PF06889.11 KZN86462.1 - 0.032 14.3 0.0 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) DNA_methylase PF00145.17 KZN86463.1 - 2.8e-40 138.7 0.0 2.8e-27 95.9 0.0 2.1 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase GATase_6 PF13522.6 KZN86464.1 - 2.1e-13 50.6 0.0 6.7e-13 49.0 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KZN86464.1 - 1.1e-10 41.4 0.0 2.4e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KZN86464.1 - 2.2e-07 30.5 0.0 7.7e-07 28.8 0.0 1.9 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 KZN86464.1 - 4.4e-05 22.5 0.0 0.0001 21.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PRTase_2 PF15609.6 KZN86464.1 - 0.055 13.0 0.0 0.16 11.4 0.0 1.7 1 1 0 1 1 1 0 Phosphoribosyl transferase DNA_photolyase PF00875.18 KZN86464.1 - 0.14 12.1 0.0 0.47 10.4 0.0 1.8 2 0 0 2 2 2 0 DNA photolyase HhH-GPD PF00730.25 KZN86465.1 - 7.4e-07 29.6 0.0 1.4e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KZN86465.1 - 0.022 14.6 0.0 0.075 12.9 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.6 KZN86465.1 - 0.027 15.1 0.0 0.39 11.4 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain DUF2400 PF09674.10 KZN86465.1 - 0.18 11.7 0.0 7.3 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) Aldedh PF00171.22 KZN86466.1 - 8.8e-121 403.6 0.0 1.1e-120 403.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Herpes_UL14 PF03580.14 KZN86467.1 - 0.058 13.6 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus UL14-like protein ADH_N PF08240.12 KZN86468.1 - 0.0019 18.1 2.0 0.0021 17.9 2.0 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF5379 PF17350.2 KZN86468.1 - 0.025 14.9 0.8 0.026 14.8 0.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5379) Clostridium_P47 PF06597.11 KZN86468.1 - 0.089 11.5 3.5 0.098 11.4 3.5 1.0 1 0 0 1 1 1 0 Clostridium P-47 protein Protocadherin PF08374.11 KZN86468.1 - 0.1 12.6 1.2 0.094 12.7 1.2 1.1 1 0 0 1 1 1 0 Protocadherin Adeno_E3_CR2 PF02439.15 KZN86468.1 - 5.1 6.9 12.4 0.19 11.5 5.6 2.1 2 1 1 3 3 3 0 Adenovirus E3 region protein CR2 Mt_ATP-synt_D PF05873.12 KZN86470.1 - 1.3e-23 83.6 1.6 1.6e-23 83.3 1.6 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) CheZ PF04344.13 KZN86470.1 - 0.022 14.7 1.5 0.036 14.0 1.4 1.4 1 1 0 1 1 1 0 Chemotaxis phosphatase, CheZ T2SSM_b PF10741.9 KZN86470.1 - 0.055 13.3 0.2 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b ATPase PF06745.13 KZN86470.1 - 0.096 12.0 0.3 0.14 11.5 0.3 1.2 1 0 0 1 1 1 0 KaiC DUF2408 PF10303.9 KZN86470.1 - 0.097 13.2 1.7 0.15 12.6 1.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Spectrin PF00435.21 KZN86470.1 - 0.13 12.8 4.6 0.92 10.0 1.3 2.2 1 1 0 2 2 2 0 Spectrin repeat FlaC_arch PF05377.11 KZN86470.1 - 0.32 11.4 1.9 3.6 8.1 0.5 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF948 PF06103.11 KZN86470.1 - 0.48 10.7 2.8 3.8 7.8 0.2 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DHR10 PF18595.1 KZN86470.1 - 0.84 9.7 6.2 0.16 12.0 2.0 2.0 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain NAC PF01849.18 KZN86471.1 - 4.8e-22 77.7 0.0 8.8e-21 73.6 0.0 2.2 2 0 0 2 2 2 1 NAC domain CENP-B_dimeris PF09026.10 KZN86471.1 - 0.064 13.6 4.9 26 5.3 5.9 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RR_TM4-6 PF06459.12 KZN86471.1 - 0.39 10.5 6.1 7 6.4 3.4 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 NESP55 PF06390.12 KZN86471.1 - 0.49 10.0 10.3 0.056 13.0 5.0 1.9 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) Ribosomal_L14e PF01929.17 KZN86472.1 - 1.5e-27 95.9 0.3 2.3e-27 95.3 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 KZN86472.1 - 1.4e-07 31.2 0.2 2.7e-07 30.3 0.2 1.5 1 0 0 1 1 1 1 KOW motif YIF1 PF03878.15 KZN86473.1 - 6.4e-99 330.3 4.0 7.4e-99 330.1 4.0 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 KZN86473.1 - 2.8e-05 23.9 5.0 2.8e-05 23.9 5.0 1.5 2 0 0 2 2 2 1 Yip1 domain SRP-alpha_N PF04086.13 KZN86474.1 - 9.7e-77 258.7 0.0 1.3e-76 258.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 KZN86474.1 - 1.9e-50 171.2 0.0 3.3e-50 170.5 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KZN86474.1 - 3e-09 37.0 0.0 8.3e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 KZN86474.1 - 2.2e-07 30.1 0.0 3.8e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KZN86474.1 - 0.00044 20.0 0.0 0.00081 19.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KZN86474.1 - 0.0042 16.8 0.1 0.016 14.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KZN86474.1 - 0.012 16.0 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain CbiA PF01656.23 KZN86474.1 - 0.018 15.1 0.0 0.095 12.8 0.0 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 KZN86474.1 - 0.051 13.7 0.1 0.49 10.5 0.1 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_31 PF13614.6 KZN86474.1 - 0.058 13.3 0.1 0.44 10.4 0.0 2.0 1 1 1 2 2 2 0 AAA domain Fer4_NifH PF00142.18 KZN86474.1 - 0.081 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ABC_tran PF00005.27 KZN86474.1 - 0.1 13.1 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter MHCassoc_trimer PF08831.10 KZN86475.1 - 0.21 11.6 0.7 0.5 10.4 0.7 1.5 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain p450 PF00067.22 KZN86476.1 - 1.2e-44 152.9 0.4 1.9e-32 112.6 0.1 2.1 2 0 0 2 2 2 2 Cytochrome P450 ERG4_ERG24 PF01222.17 KZN86477.1 - 9.8e-147 489.2 17.8 1.2e-146 488.8 17.8 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family p450 PF00067.22 KZN86477.1 - 1.4e-17 63.7 0.0 4.7e-17 61.9 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 MFS_1 PF07690.16 KZN86478.1 - 4.9e-36 124.4 22.5 7.5e-27 94.2 0.4 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN86478.1 - 3.7e-09 36.0 14.1 5.2e-09 35.5 2.1 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 KZN86478.1 - 1.3e-05 24.2 0.4 1.3e-05 24.2 0.4 2.7 2 1 0 2 2 2 1 MFS_1 like family MFS_4 PF06779.14 KZN86478.1 - 0.00069 19.0 3.0 0.00069 19.0 3.0 2.4 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 KZN86478.1 - 0.017 13.5 0.7 0.03 12.8 0.7 1.3 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Polysacc_lyase PF14099.6 KZN86480.1 - 4e-20 72.6 1.7 4.1e-20 72.5 1.7 1.0 1 0 0 1 1 1 1 Polysaccharide lyase DUF1080 PF06439.11 KZN86480.1 - 0.007 16.5 0.1 0.0074 16.4 0.1 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) Ank_2 PF12796.7 KZN86481.1 - 0.00023 21.7 0.0 0.0027 18.2 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KZN86481.1 - 0.0014 19.0 0.1 10 7.1 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Rieske PF00355.26 KZN86482.1 - 8.2e-17 60.9 0.0 1.4e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.19 KZN86483.1 - 4.3e-23 82.4 1.0 6.7e-11 42.6 0.0 2.1 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) RabGAP-TBC PF00566.18 KZN86484.1 - 1.6e-40 139.1 0.8 3.2e-40 138.1 0.8 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 KZN86484.1 - 4.8e-07 29.4 0.0 0.023 14.2 0.0 3.2 2 1 0 2 2 2 2 Rab-binding domain (RBD) GAS2 PF02187.17 KZN86485.1 - 3.6e-06 27.0 0.1 7.8e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Hexokinase_2 PF03727.16 KZN86486.1 - 3.5e-73 246.0 0.0 4.6e-73 245.6 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KZN86486.1 - 5.1e-64 215.9 0.0 7e-64 215.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hus1 PF04005.12 KZN86487.1 - 5.4e-94 314.6 0.0 6.5e-94 314.3 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Sec16_C PF12931.7 KZN86488.1 - 7.2e-107 357.5 0.0 1e-106 357.0 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16_N PF12935.7 KZN86488.1 - 1e-78 264.8 21.5 1e-78 264.8 21.5 4.8 3 2 1 4 4 4 2 Vesicle coat trafficking protein Sec16 N-terminus Sec16 PF12932.7 KZN86488.1 - 1.5e-34 119.1 0.0 4.1e-34 117.7 0.0 1.8 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region PhoLip_ATPase_C PF16212.5 KZN86489.1 - 7.7e-48 163.4 7.9 7.7e-48 163.4 7.9 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KZN86489.1 - 2e-16 59.4 2.2 4.1e-16 58.4 2.2 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KZN86489.1 - 8.7e-14 52.3 1.3 7.3e-11 42.7 1.3 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KZN86489.1 - 1.6e-07 31.3 0.0 4.1e-06 26.8 0.0 2.7 3 0 0 3 3 3 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KZN86489.1 - 2.1e-06 27.4 1.9 0.0029 17.2 0.0 3.2 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase_3 PF08282.12 KZN86489.1 - 0.004 16.9 0.0 0.0088 15.8 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase YiaAB PF05360.14 KZN86489.1 - 0.07 13.4 0.1 3.1 8.1 0.6 2.9 1 1 1 2 2 2 0 yiaA/B two helix domain HIGH_NTase1_ass PF16581.5 KZN86489.1 - 0.091 12.7 0.1 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 Cytidyltransferase-related C-terminal region Ribosomal_L28e PF01778.17 KZN86490.1 - 3.9e-38 130.7 1.3 7.2e-38 129.9 1.3 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 KZN86490.1 - 2.4e-30 105.1 10.5 2.4e-30 105.1 10.5 2.4 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 KZN86490.1 - 6.4e-06 25.8 15.0 7.9e-06 25.5 15.0 1.1 1 0 0 1 1 1 1 BUD22 CDC45 PF02724.14 KZN86490.1 - 3.2 5.9 18.2 1.1 7.5 14.1 1.9 2 0 0 2 2 2 0 CDC45-like protein TFIIF_alpha PF05793.12 KZN86490.1 - 3.6 6.1 24.4 5.9 5.4 24.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 KZN86490.1 - 3.7 5.6 22.4 4.7 5.3 22.4 1.2 1 0 0 1 1 1 0 Nop14-like family SGT1 PF07093.11 KZN86490.1 - 6.1 5.2 10.4 9 4.6 10.4 1.2 1 0 0 1 1 1 0 SGT1 protein SAPS PF04499.15 KZN86490.1 - 7 5.3 8.2 9.1 4.9 8.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mso1_Sec1_bdg PF14475.6 KZN86491.1 - 4.1e-13 48.7 0.0 7.2e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Sugar_tr PF00083.24 KZN86492.1 - 6.2e-86 289.0 18.1 7.5e-86 288.8 18.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN86492.1 - 9.1e-29 100.5 24.4 9.1e-29 100.5 24.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KZN86492.1 - 4.2e-08 32.1 5.6 1.5e-07 30.3 1.0 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF1129 PF06570.11 KZN86492.1 - 0.79 9.2 4.3 0.36 10.3 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF4131 PF13567.6 KZN86492.1 - 5.2 6.7 7.3 3 7.4 0.6 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUF3638 PF12340.8 KZN86493.1 - 8.3e-96 319.7 0.2 2.1e-95 318.4 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KZN86493.1 - 3.5e-17 61.5 0.3 8e-17 60.3 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) OTT_1508_deam PF14441.6 KZN86494.1 - 1.2e-20 73.3 2.9 2.6e-20 72.2 2.9 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase Fig1 PF12351.8 KZN86496.1 - 8.8e-30 104.0 0.1 1.1e-29 103.7 0.1 1.0 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 Arv1 PF04161.13 KZN86496.1 - 0.069 13.3 0.0 0.076 13.2 0.0 1.1 1 0 0 1 1 1 0 Arv1-like family SPT_ssu-like PF11779.8 KZN86496.1 - 0.21 11.2 1.8 0.79 9.4 1.6 2.1 2 0 0 2 2 2 0 Small subunit of serine palmitoyltransferase-like AATase PF07247.12 KZN86497.1 - 8.3e-13 47.7 0.0 1.9e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol acetyltransferase CorA PF01544.18 KZN86497.1 - 8e-07 28.7 0.6 8e-07 28.7 0.6 3.0 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein WES_acyltransf PF03007.16 KZN86497.1 - 0.00053 19.8 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain RNA_polI_A34 PF08208.11 KZN86497.1 - 0.091 12.8 0.5 0.17 12.0 0.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Oxidored_FMN PF00724.20 KZN86498.1 - 1.6e-94 317.0 0.0 1.8e-94 316.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Fungal_trans_2 PF11951.8 KZN86499.1 - 1.8e-05 23.7 0.1 3.4e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain EBP PF05241.12 KZN86500.1 - 0.027 13.9 0.2 0.044 13.3 0.2 1.2 1 0 0 1 1 1 0 Emopamil binding protein Glyoxalase PF00903.25 KZN86501.1 - 3.1e-09 37.1 3.1 9.2e-08 32.3 1.3 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily UreD PF01774.17 KZN86502.1 - 5.1e-70 235.7 0.0 6e-70 235.5 0.0 1.0 1 0 0 1 1 1 1 UreD urease accessory protein Amidohydro_1 PF01979.20 KZN86503.1 - 4e-67 227.0 0.4 8e-67 226.0 0.4 1.5 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 KZN86503.1 - 2.2e-52 176.5 1.2 4.6e-52 175.4 1.2 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 KZN86503.1 - 1.7e-38 130.6 0.0 3.4e-38 129.6 0.0 1.5 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 KZN86503.1 - 4.1e-14 52.7 0.1 9.5e-14 51.5 0.1 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 KZN86503.1 - 5.6e-10 39.3 0.0 7.8e-06 25.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family DUF3402 PF11882.8 KZN86504.1 - 3.3e-194 646.3 0.0 4.8e-194 645.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 KZN86504.1 - 3.3e-86 289.0 0.0 5.1e-86 288.4 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein TbpB_C PF17483.2 KZN86504.1 - 0.058 13.8 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 C-lobe handle domain of Tf-binding protein B PAP2 PF01569.21 KZN86505.1 - 1.4e-14 54.0 4.7 1.4e-14 54.0 4.7 2.1 1 1 3 4 4 4 1 PAP2 superfamily DUF212 PF02681.14 KZN86505.1 - 0.00018 21.6 0.2 0.0095 16.1 0.1 2.3 1 1 1 2 2 2 1 Divergent PAP2 family DUF4131 PF13567.6 KZN86505.1 - 1.3 8.7 7.7 0.18 11.5 2.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) IBR PF01485.21 KZN86506.1 - 4e-18 65.4 44.4 2.3e-14 53.4 7.6 4.3 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 KZN86506.1 - 4.1e-17 62.5 0.0 6.6e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 RWD domain zf-RING_5 PF14634.6 KZN86506.1 - 0.0019 18.1 10.5 0.0019 18.1 10.5 3.8 3 1 1 4 4 4 1 zinc-RING finger domain zf-RING_11 PF17123.5 KZN86506.1 - 0.0028 17.4 5.4 0.0028 17.4 5.4 2.9 4 0 0 4 4 4 1 RING-like zinc finger zf-RING_2 PF13639.6 KZN86506.1 - 0.0059 16.9 10.2 0.0059 16.9 10.2 4.6 5 1 1 6 6 6 2 Ring finger domain Lipase_GDSL_2 PF13472.6 KZN86507.1 - 4.9e-15 56.4 0.2 6.5e-15 56.0 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KZN86507.1 - 4.7e-07 30.0 0.1 7.8e-06 26.0 0.1 2.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase tRNA-synt_2c PF01411.19 KZN86507.1 - 0.16 10.5 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (A) Cofilin_ADF PF00241.20 KZN86508.1 - 2.6e-29 101.5 0.1 2.8e-29 101.4 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein F-box-like PF12937.7 KZN86509.1 - 0.0022 17.8 0.0 0.0062 16.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like CRT10 PF08728.10 KZN86510.1 - 1.3e-19 69.9 0.0 1e-11 43.8 0.0 2.1 2 0 0 2 2 2 2 CRT10 MMtag PF10159.9 KZN86511.1 - 9.6e-35 118.7 3.4 1.6e-34 118.0 3.4 1.3 1 0 0 1 1 1 1 Multiple myeloma tumor-associated Phage_Nu1 PF07471.12 KZN86511.1 - 0.23 11.2 2.8 0.61 9.8 2.5 1.9 2 0 0 2 2 2 0 Phage DNA packaging protein Nu1 Glyco_hydro_63 PF03200.16 KZN86512.1 - 1.3e-174 581.6 3.0 1.7e-173 577.9 3.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KZN86512.1 - 1.1e-88 297.1 0.0 3e-88 295.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 KZN86512.1 - 0.0013 17.7 2.5 0.0037 16.2 2.1 1.8 1 1 0 1 1 1 1 Trehalase DAO PF01266.24 KZN86513.1 - 4.4e-69 233.7 0.5 5e-69 233.5 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KZN86513.1 - 3.2e-06 27.3 0.2 6.9e-06 26.2 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KZN86513.1 - 5.6e-06 25.8 0.2 0.016 14.4 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KZN86513.1 - 0.00013 21.0 0.3 0.0029 16.5 0.2 2.0 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.27 KZN86513.1 - 0.0015 19.0 0.2 0.0068 16.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KZN86513.1 - 0.0022 17.3 0.2 0.004 16.4 0.2 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KZN86513.1 - 0.0035 17.3 0.6 0.059 13.3 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KZN86513.1 - 0.006 15.7 0.7 0.82 8.7 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain MCRA PF06100.11 KZN86513.1 - 0.012 14.4 0.1 0.021 13.6 0.1 1.3 1 0 0 1 1 1 0 MCRA family Mqo PF06039.15 KZN86513.1 - 0.021 13.4 0.0 0.19 10.2 0.0 1.9 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Sacchrp_dh_NADP PF03435.18 KZN86513.1 - 0.056 13.7 0.2 0.78 10.0 0.1 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Prenylcys_lyase PF07156.14 KZN86513.1 - 0.13 11.4 0.1 0.18 10.9 0.1 1.1 1 0 0 1 1 1 0 Prenylcysteine lyase SNRNP27 PF08648.12 KZN86514.1 - 2e-26 91.8 2.5 4.2e-26 90.8 2.5 1.6 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins AMP-binding PF00501.28 KZN86515.1 - 7e-75 252.2 0.0 1.1e-74 251.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KZN86515.1 - 1e-32 113.3 0.0 1.9e-32 112.5 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KZN86515.1 - 6.5e-05 22.5 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 KZN86515.1 - 0.00015 22.7 0.0 0.00048 21.0 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 KZN86515.1 - 0.12 12.8 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site Zn_clus PF00172.18 KZN86516.1 - 3.8e-07 30.1 12.2 7.9e-07 29.1 12.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alpha-amylase PF00128.24 KZN86517.1 - 1.1e-109 367.1 0.4 3.3e-109 365.5 0.1 1.7 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KZN86517.1 - 0.00022 21.3 0.0 0.00056 20.0 0.0 1.7 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Glyco_hydro_42C PF08533.10 KZN86517.1 - 0.12 12.2 0.0 0.36 10.6 0.0 1.8 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain Sugar_tr PF00083.24 KZN86518.1 - 2e-85 287.3 19.0 2.3e-85 287.1 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN86518.1 - 2.9e-16 59.4 28.0 9e-16 57.7 22.9 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily YtpI PF14007.6 KZN86518.1 - 0.34 11.1 3.7 0.35 11.0 0.3 2.4 2 0 0 2 2 2 0 YtpI-like protein Elong_Iki1 PF10483.9 KZN86519.1 - 5.3e-101 338.1 0.0 6.1e-101 337.8 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 Longin PF13774.6 KZN86520.1 - 5.2e-26 90.5 0.6 8.1e-26 89.9 0.6 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KZN86520.1 - 2.8e-14 52.6 0.0 5.7e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Synaptobrevin SLM4 PF16818.5 KZN86520.1 - 0.065 13.2 0.4 0.48 10.4 0.0 2.1 1 1 1 2 2 2 0 Protein SLM4 EMP24_GP25L PF01105.24 KZN86520.1 - 0.073 13.0 0.3 0.16 11.9 0.1 1.6 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD ASXH PF13919.6 KZN86521.1 - 1.9e-37 128.4 1.2 4.1e-37 127.3 1.2 1.6 1 0 0 1 1 1 1 Asx homology domain adh_short PF00106.25 KZN86522.1 - 6.5e-24 84.5 0.0 1.4e-23 83.4 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN86522.1 - 1.6e-15 57.3 0.0 2.8e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN86522.1 - 0.00062 19.7 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 KR domain CLPTM1 PF05602.12 KZN86523.1 - 1.8e-160 534.7 0.0 2.1e-160 534.4 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) CENP-I PF07778.11 KZN86524.1 - 1.1e-39 136.6 0.3 4.4e-39 134.6 0.3 1.7 1 1 0 1 1 1 1 Mis6 Transcrip_reg PF01709.20 KZN86525.1 - 3.4e-70 236.2 0.4 3.9e-70 236.0 0.4 1.0 1 0 0 1 1 1 1 Transcriptional regulator NapD PF03927.13 KZN86525.1 - 0.1 12.6 0.9 5.4 7.2 0.0 3.0 2 1 1 3 3 3 0 NapD protein HEAT_2 PF13646.6 KZN86526.1 - 3.5e-10 40.2 1.2 0.0064 16.9 0.0 5.7 4 1 1 5 5 5 4 HEAT repeats HEAT PF02985.22 KZN86526.1 - 1.4e-08 34.2 9.5 0.096 13.0 0.0 8.4 9 0 0 9 9 9 3 HEAT repeat AAA_6 PF12774.7 KZN86526.1 - 0.062 12.3 0.4 0.12 11.3 0.4 1.4 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region HEAT_EZ PF13513.6 KZN86526.1 - 0.089 13.3 14.9 2.8 8.5 0.0 7.2 8 0 0 8 8 8 0 HEAT-like repeat Nuc_recep-AF1 PF11825.8 KZN86526.1 - 0.097 12.7 0.1 0.34 11.0 0.1 1.9 1 0 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 Transp_cyt_pur PF02133.15 KZN86528.1 - 8.9e-26 90.6 38.7 1.5e-25 89.9 38.7 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin LapA_dom PF06305.11 KZN86528.1 - 0.97 9.3 2.8 2.8 7.8 0.2 3.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Arylsulfotran_2 PF14269.6 KZN86529.1 - 8.1e-14 51.7 0.0 1.5e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KZN86529.1 - 1.7e-13 50.2 1.0 6.8e-08 31.8 0.1 3.8 2 2 2 4 4 4 3 Arylsulfotransferase (ASST) PQQ_2 PF13360.6 KZN86529.1 - 7.9e-05 22.4 0.1 0.00096 18.8 0.1 2.2 2 0 0 2 2 2 1 PQQ-like domain PQQ PF01011.21 KZN86529.1 - 0.061 13.3 0.2 10 6.3 0.0 3.7 3 0 0 3 3 3 0 PQQ enzyme repeat DUF1640 PF07798.11 KZN86530.1 - 1.9e-40 138.8 6.9 2.7e-40 138.2 6.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) LCIB_C_CA PF18599.1 KZN86530.1 - 0.23 10.7 1.1 0.39 10.0 1.1 1.2 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases HIP1_clath_bdg PF16515.5 KZN86530.1 - 0.41 11.3 7.7 0.25 12.0 4.1 2.4 1 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 UvrD-helicase PF00580.21 KZN86531.1 - 1.8e-12 47.5 0.0 1.9e-08 34.2 0.0 2.8 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KZN86531.1 - 3.5e-07 29.9 0.0 0.00016 21.2 0.0 3.8 2 2 2 4 4 4 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KZN86531.1 - 2.5e-06 27.9 0.0 1.6e-05 25.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 KZN86531.1 - 6.2e-06 25.9 0.1 0.013 15.3 0.2 2.6 1 1 1 2 2 2 2 UvrD-like helicase C-terminal domain SNAP PF14938.6 KZN86531.1 - 2.2e-05 24.0 3.2 8.6e-05 22.1 3.2 2.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP Clathrin PF00637.20 KZN86531.1 - 0.025 14.4 1.0 0.34 10.8 0.1 3.2 2 2 0 2 2 2 0 Region in Clathrin and VPS AAA_30 PF13604.6 KZN86531.1 - 0.03 14.0 0.5 4.9 6.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_12 PF13087.6 KZN86531.1 - 0.045 13.4 0.0 0.65 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KZN86531.1 - 0.047 14.0 0.2 1.3 9.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain TPR_8 PF13181.6 KZN86531.1 - 0.063 13.5 3.7 7.6 7.0 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KZN86531.1 - 1.1 9.5 16.0 6.8 7.1 0.2 5.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KZN86531.1 - 3.9 7.5 9.4 4.1 7.4 0.1 4.8 4 1 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 KZN86531.1 - 5.6 7.2 5.9 39 4.6 2.4 3.5 2 1 0 2 2 2 0 Tetratricopeptide repeat Vps51 PF08700.11 KZN86532.1 - 2e-14 53.4 0.0 3e-13 49.6 0.0 2.7 2 0 0 2 2 2 1 Vps51/Vps67 YbaB_DNA_bd PF02575.16 KZN86532.1 - 0.023 14.9 0.0 0.11 12.7 0.0 2.2 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family SesA PF17107.5 KZN86532.1 - 0.13 12.5 1.1 1.1 9.4 0.2 3.1 2 1 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases NPV_P10 PF05531.12 KZN86532.1 - 3.8 8.0 7.5 9.2 6.8 0.1 4.5 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Apolipoprotein PF01442.18 KZN86532.1 - 5.8 6.7 7.5 12 5.7 0.1 4.3 4 1 0 4 4 4 0 Apolipoprotein A1/A4/E domain D123 PF07065.14 KZN86533.1 - 2.2e-110 368.6 0.7 3e-110 368.2 0.7 1.2 1 0 0 1 1 1 1 D123 ECH_1 PF00378.20 KZN86534.1 - 4e-26 91.8 0.0 5.6e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KZN86534.1 - 1.3e-18 67.6 0.0 1.4e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pet100 PF09803.9 KZN86535.1 - 8.7e-19 67.8 0.1 1.1e-18 67.5 0.1 1.2 1 0 0 1 1 1 1 Pet100 TMEM247 PF15444.6 KZN86535.1 - 0.044 13.8 1.2 0.051 13.6 1.2 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 SPT_ssu-like PF11779.8 KZN86536.1 - 1.1e-23 82.5 3.4 1.9e-23 81.8 3.4 1.4 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like RF-1 PF00472.20 KZN86537.1 - 4.8e-26 91.0 1.2 7.8e-26 90.3 1.2 1.2 1 0 0 1 1 1 1 RF-1 domain RE_NgoFVII PF09565.10 KZN86537.1 - 0.039 13.2 0.6 0.048 13.0 0.6 1.2 1 0 0 1 1 1 0 NgoFVII restriction endonuclease PseudoU_synth_2 PF00849.22 KZN86537.1 - 0.077 13.1 1.3 9.2 6.3 0.2 2.1 1 1 1 2 2 2 0 RNA pseudouridylate synthase Paf1 PF03985.13 KZN86537.1 - 0.68 8.9 5.3 0.85 8.6 5.3 1.1 1 0 0 1 1 1 0 Paf1 CAS_CSE1 PF03378.15 KZN86538.1 - 6.4e-197 654.4 0.9 1.3e-196 653.4 0.9 1.6 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 KZN86538.1 - 4.6e-159 529.2 0.9 6.8e-159 528.6 0.9 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 KZN86538.1 - 1.5e-14 53.7 0.1 6.5e-14 51.6 0.1 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KZN86538.1 - 0.01 15.9 1.2 0.77 9.8 0.0 3.4 4 0 0 4 4 4 0 Exportin 1-like protein DUF1529 PF07485.11 KZN86538.1 - 0.026 14.4 0.0 0.084 12.8 0.0 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1259) CTP_synth_N PF06418.14 KZN86539.1 - 2.3e-121 404.1 0.0 3.1e-121 403.7 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KZN86539.1 - 1.2e-54 185.0 0.0 2.1e-54 184.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KZN86539.1 - 1.3e-06 28.4 0.2 8.5e-06 25.7 0.2 2.2 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 KZN86539.1 - 0.078 13.0 0.0 0.13 12.4 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF3384 PF11864.8 KZN86540.1 - 2.1e-112 376.5 4.4 2.1e-112 376.5 4.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 KZN86540.1 - 1.3e-46 158.5 0.0 2.1e-46 157.8 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 KZN86540.1 - 2.1e-40 138.9 0.0 1.3e-34 119.9 0.0 3.4 3 0 0 3 3 3 3 Tuberin CRISPR_Cse2 PF09485.10 KZN86540.1 - 0.86 10.1 4.5 3.6 8.1 0.4 3.6 3 0 0 3 3 3 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Fungal_trans PF04082.18 KZN86541.1 - 0.0013 17.8 0.2 0.0022 17.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN86541.1 - 0.36 11.0 6.2 0.051 13.7 1.7 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_16 PF00722.21 KZN86542.1 - 4.4e-45 153.3 5.2 4.4e-45 153.3 5.2 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 CIA30 PF08547.12 KZN86542.1 - 0.013 15.5 0.6 0.023 14.7 0.6 1.4 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) Phosphodiest PF01663.22 KZN86543.1 - 3.3e-15 56.5 0.3 5.3e-15 55.9 0.3 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KZN86543.1 - 7.5e-06 25.5 0.3 1.6e-05 24.4 0.3 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KZN86543.1 - 8.4e-06 25.4 0.1 1.5e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Sulfatase PglZ PF08665.12 KZN86543.1 - 0.25 11.4 1.6 16 5.6 0.1 2.2 2 0 0 2 2 2 0 PglZ domain Gly-zipper_YMGG PF13441.6 KZN86543.1 - 0.4 10.5 11.4 1 9.1 11.4 1.6 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 KZN86543.1 - 6.5 6.8 12.9 16 5.6 12.9 1.7 1 0 0 1 1 1 0 Glycine zipper DUF5326 PF17260.2 KZN86544.1 - 0.0053 16.9 0.5 0.0084 16.2 0.5 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5326) SP_C-Propep PF08999.10 KZN86544.1 - 0.035 13.9 0.9 0.16 11.8 0.1 2.1 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide DUF4083 PF13314.6 KZN86544.1 - 0.048 13.6 0.6 0.08 12.9 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) DUF3377 PF11857.8 KZN86544.1 - 0.079 12.9 0.3 0.29 11.1 0.0 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) PUF PF00806.19 KZN86545.1 - 1.2e-60 197.9 11.9 8.4e-10 37.8 0.3 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 KZN86545.1 - 0.016 15.6 2.6 24 5.3 0.8 4.2 1 1 4 5 5 5 0 CPL (NUC119) domain PLN_propep PF16485.5 KZN86545.1 - 0.14 11.9 0.4 0.55 10.0 0.1 2.3 2 0 0 2 2 2 0 Protealysin propeptide DUF234 PF03008.14 KZN86545.1 - 0.19 12.2 2.1 0.52 10.8 0.1 2.6 4 0 0 4 4 4 0 Archaea bacterial proteins of unknown function LOB PF03195.14 KZN86545.1 - 0.55 10.8 2.8 5.8 7.6 0.2 3.8 3 2 2 5 5 5 0 Lateral organ boundaries (LOB) domain ParD PF09386.10 KZN86545.1 - 2.9 8.4 4.7 72 3.9 0.0 4.4 4 2 2 6 6 6 0 Antitoxin ParD cwf21 PF08312.12 KZN86546.1 - 1.7e-16 60.1 23.0 1.7e-16 60.1 23.0 2.3 2 1 0 2 2 2 1 cwf21 domain DUF1690 PF07956.11 KZN86546.1 - 2.5 8.5 11.4 0.33 11.4 7.5 1.5 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Atg14 PF10186.9 KZN86546.1 - 3.7 6.6 5.7 4.7 6.2 5.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HA2 PF04408.23 KZN86547.1 - 1e-27 96.5 0.0 1e-27 96.5 0.0 3.0 4 0 0 4 4 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KZN86547.1 - 3.9e-12 46.5 0.1 1.7e-11 44.4 0.0 2.1 2 0 0 2 2 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KZN86547.1 - 2.7e-08 33.8 0.0 7e-07 29.2 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 KZN86547.1 - 4.2e-08 33.4 0.0 1e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_23 PF13476.6 KZN86547.1 - 0.00076 20.0 14.1 0.034 14.6 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KZN86547.1 - 0.0018 18.6 0.6 0.012 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KZN86547.1 - 0.0024 17.9 0.0 2.8 7.9 0.0 3.1 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KZN86547.1 - 0.0045 17.3 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KZN86547.1 - 0.0053 15.8 0.2 0.1 11.7 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 KZN86547.1 - 0.0057 16.4 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KZN86547.1 - 0.0088 15.3 1.2 0.012 14.9 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KZN86547.1 - 0.11 11.9 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein ATPase_2 PF01637.18 KZN86547.1 - 0.95 9.3 3.7 3.2 7.6 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Gastrin PF00918.17 KZN86547.1 - 6.6 7.7 8.1 6.9 7.7 0.1 2.9 2 0 0 2 2 2 0 Gastrin/cholecystokinin family PAC3 PF10178.9 KZN86548.1 - 5.2e-07 29.7 0.0 8.5e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 POC3_POC4 PF10448.9 KZN86548.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 20S proteasome chaperone assembly proteins 3 and 4 Tyr-DNA_phospho PF06087.12 KZN86550.1 - 2.9e-81 273.6 0.0 6.5e-81 272.4 0.0 1.5 2 0 0 2 2 2 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 KZN86550.1 - 0.00012 21.9 0.0 0.022 14.7 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain UIM PF02809.20 KZN86550.1 - 0.0016 18.2 10.2 0.0032 17.3 0.8 3.0 3 0 0 3 3 3 2 Ubiquitin interaction motif ABC2_membrane PF01061.24 KZN86551.1 - 8.8e-81 270.3 54.7 2.3e-42 144.8 20.6 3.0 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 KZN86551.1 - 5.6e-39 133.8 0.1 1.3e-20 74.4 0.0 3.0 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 KZN86551.1 - 5.3e-30 103.2 4.5 3.9e-26 90.8 0.0 3.2 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KZN86551.1 - 9.8e-17 61.4 1.0 9.8e-17 61.4 1.0 2.3 2 0 0 2 2 1 1 ABC-transporter N-terminal AAA_18 PF13238.6 KZN86551.1 - 5.3e-07 30.2 0.0 7.7e-05 23.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KZN86551.1 - 2e-05 25.0 0.0 0.0089 16.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KZN86551.1 - 2.5e-05 24.5 0.0 0.002 18.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KZN86551.1 - 2.8e-05 24.1 0.2 0.001 19.0 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 KZN86551.1 - 2.8e-05 24.1 0.0 0.015 15.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KZN86551.1 - 0.00022 21.3 0.4 0.11 12.6 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KZN86551.1 - 0.00025 20.7 0.1 0.5 10.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 KZN86551.1 - 0.00071 18.8 15.4 0.00071 18.8 15.4 2.9 2 1 0 2 2 1 1 ABC-2 family transporter protein AAA_22 PF13401.6 KZN86551.1 - 0.0013 19.0 0.4 0.067 13.5 0.0 3.2 3 1 1 4 4 3 1 AAA domain AAA_25 PF13481.6 KZN86551.1 - 0.0013 18.3 0.2 0.41 10.2 0.2 2.7 3 0 0 3 3 2 1 AAA domain cobW PF02492.19 KZN86551.1 - 0.0014 18.2 0.8 0.0051 16.4 0.1 2.2 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 KZN86551.1 - 0.003 17.0 0.0 0.055 12.9 0.0 2.7 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 KZN86551.1 - 0.0035 17.6 0.0 0.0035 17.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 KZN86551.1 - 0.0043 16.8 0.0 0.24 11.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 KZN86551.1 - 0.0082 16.1 0.8 0.3 11.0 0.4 2.5 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 KZN86551.1 - 0.046 14.1 0.1 9.8 6.6 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KZN86551.1 - 0.05 13.6 0.6 0.52 10.3 0.3 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KZN86551.1 - 0.11 12.2 3.1 3.5 7.3 0.5 2.9 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KZN86551.1 - 0.12 11.7 0.1 6.7 6.0 0.1 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Septin PF00735.18 KZN86551.1 - 0.15 11.3 0.3 0.5 9.6 0.1 1.9 2 0 0 2 2 2 0 Septin NB-ARC PF00931.22 KZN86551.1 - 0.17 11.1 0.3 4.3 6.4 0.2 2.4 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.12 KZN86551.1 - 0.26 10.6 1.5 1.1 8.5 0.4 2.4 2 0 0 2 2 2 0 Zeta toxin Dehydrin PF00257.19 KZN86551.1 - 4.9 7.7 10.4 17 5.9 10.4 2.0 1 0 0 1 1 1 0 Dehydrin AAA_17 PF13207.6 KZN86551.1 - 6.3 7.2 7.2 0.9 10.0 0.3 2.7 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.6 KZN86551.1 - 8.4 6.8 7.7 9.4 6.7 0.1 3.4 3 1 0 3 3 3 0 AAA domain CDP-OH_P_transf PF01066.21 KZN86552.1 - 1.2e-14 54.9 0.8 1.2e-14 54.9 0.8 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Gti1_Pac2 PF09729.9 KZN86554.1 - 6e-63 212.2 0.0 2.1e-62 210.4 0.0 1.8 2 0 0 2 2 2 1 Gti1/Pac2 family GIDA PF01134.22 KZN86555.1 - 3.1e-154 513.8 0.0 3.8e-154 513.5 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KZN86555.1 - 6.9e-67 225.7 0.0 9.2e-67 225.3 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 KZN86555.1 - 3.8e-06 26.5 1.6 6.5e-06 25.8 1.6 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KZN86555.1 - 1.1e-05 24.8 1.0 1.9e-05 24.0 0.6 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KZN86555.1 - 0.0014 17.8 2.3 0.0014 17.8 2.3 1.9 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 KZN86555.1 - 0.0015 17.9 0.3 0.0038 16.6 0.2 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KZN86555.1 - 0.025 13.3 0.4 0.26 9.9 0.3 2.2 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.14 KZN86555.1 - 0.17 10.7 0.4 7.2 5.3 0.3 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.12 KZN86555.1 - 0.18 10.8 0.0 0.32 10.0 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 KZN86555.1 - 0.38 10.3 2.3 14 5.1 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase ARD PF03079.14 KZN86556.1 - 2.5e-43 148.0 0.0 3.2e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KZN86556.1 - 5.4e-09 35.6 0.0 9.6e-09 34.8 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KZN86556.1 - 0.00013 21.8 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KZN86556.1 - 0.064 12.9 0.0 0.098 12.3 0.0 1.3 1 0 0 1 1 1 0 Cupin MMM1 PF10296.9 KZN86557.1 - 4.1e-130 433.7 0.0 7.1e-130 432.9 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 MFS_1 PF07690.16 KZN86557.1 - 3.5e-29 101.8 17.8 1.6e-26 93.1 22.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MscS_TM PF12794.7 KZN86557.1 - 0.9 8.3 7.4 0.37 9.6 1.4 2.4 3 0 0 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 p450 PF00067.22 KZN86558.1 - 1e-61 209.1 0.0 1.3e-61 208.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KZN86559.1 - 8.6e-22 77.4 1.3 1.1e-21 77.1 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN86559.1 - 3.4e-06 27.1 12.2 5.8e-06 26.3 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydantoinase_B PF02538.14 KZN86560.1 - 8.2e-220 730.6 0.8 1.1e-219 730.2 0.8 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KZN86560.1 - 3.3e-102 341.7 0.0 1.8e-100 336.0 0.0 2.2 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KZN86560.1 - 2.3e-56 190.3 0.2 2.9e-54 183.5 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Pyr_redox_2 PF07992.14 KZN86561.1 - 1.5e-22 80.2 0.0 2.1e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KZN86561.1 - 1.4e-17 64.0 0.0 2.1e-13 50.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KZN86561.1 - 4e-05 23.7 0.0 0.31 11.0 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KZN86561.1 - 0.0002 20.6 0.0 0.00049 19.3 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KZN86561.1 - 0.00031 19.6 0.0 0.005 15.6 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KZN86561.1 - 0.00082 18.7 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KZN86561.1 - 0.0029 17.0 0.1 0.0057 16.1 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KZN86561.1 - 0.0057 16.3 0.6 0.22 11.1 0.3 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 KZN86561.1 - 0.012 14.7 2.5 0.083 12.0 0.3 2.8 2 1 1 3 3 3 0 Glucose inhibited division protein A Thi4 PF01946.17 KZN86561.1 - 0.016 14.4 0.1 0.061 12.5 0.0 1.9 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.6 KZN86561.1 - 0.029 14.6 0.0 0.059 13.6 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KZN86561.1 - 0.11 11.5 0.1 1.2 8.1 0.2 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 KZN86561.1 - 0.15 12.7 0.1 31 5.2 0.0 3.0 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase HET PF06985.11 KZN86562.1 - 6.5e-28 97.9 2.7 1.2e-25 90.5 2.7 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SARAF PF06682.12 KZN86563.1 - 3.2e-99 332.7 1.0 5.6e-99 331.9 1.0 1.4 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis RCR PF12273.8 KZN86563.1 - 1.5e-05 25.6 0.6 3.1e-05 24.6 0.2 1.8 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red Myb_DNA-bind_7 PF15963.5 KZN86564.1 - 5.8e-29 99.8 0.2 5.8e-29 99.8 0.2 2.1 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KZN86564.1 - 7.8e-08 32.4 0.0 1.6e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain BRE1 PF08647.11 KZN86565.1 - 9.6e-27 92.9 8.9 9.6e-27 92.9 8.9 8.2 7 3 2 9 9 7 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 KZN86565.1 - 2.3e-09 37.0 6.8 4e-09 36.2 6.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KZN86565.1 - 4.4e-09 36.0 8.3 7.9e-09 35.2 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KZN86565.1 - 6.9e-08 32.2 10.2 1.3e-07 31.4 10.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KZN86565.1 - 1.3e-07 31.6 5.9 2.5e-07 30.6 5.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KZN86565.1 - 2.1e-07 31.1 7.5 3.6e-07 30.4 7.5 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KZN86565.1 - 3.4e-07 30.0 7.6 5.7e-07 29.3 7.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KZN86565.1 - 4.8e-06 26.4 10.1 8.1e-06 25.7 10.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain DUF1272 PF06906.11 KZN86565.1 - 0.0019 18.2 5.3 0.0042 17.1 5.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) zf-rbx1 PF12678.7 KZN86565.1 - 0.0031 17.8 5.0 0.012 15.9 4.5 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KZN86565.1 - 0.0066 16.6 6.4 0.012 15.7 6.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING KxDL PF10241.9 KZN86565.1 - 0.018 15.3 3.0 0.018 15.3 3.0 6.4 5 3 3 8 8 8 0 Uncharacterized conserved protein zf-RING_10 PF16685.5 KZN86565.1 - 0.034 14.3 5.8 0.092 12.9 5.8 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KZN86565.1 - 0.04 13.7 6.9 0.31 10.9 7.6 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 KZN86565.1 - 0.19 11.4 3.5 0.35 10.5 3.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DZR PF12773.7 KZN86565.1 - 0.36 10.9 6.9 0.75 9.9 6.9 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-Nse PF11789.8 KZN86565.1 - 0.42 10.5 4.0 1.2 9.0 4.0 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-H2C2_2 PF13465.6 KZN86565.1 - 0.93 10.0 2.9 6.3 7.4 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger double domain FYVE PF01363.21 KZN86565.1 - 1.1 9.5 11.3 1 9.6 6.2 2.5 1 1 1 2 2 2 0 FYVE zinc finger zf-C2H2_jaz PF12171.8 KZN86565.1 - 1.4 9.3 6.8 20 5.6 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KZN86565.1 - 1.7 8.7 6.4 2.2 8.2 2.0 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Sas6_CC PF18594.1 KZN86565.1 - 4.2 7.2 7.4 25 4.8 0.2 3.2 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain APG6_N PF17675.1 KZN86565.1 - 5.5 7.5 80.9 0.98 9.9 12.0 7.1 2 1 5 7 7 7 0 Apg6 coiled-coil region zf-ribbon_3 PF13248.6 KZN86565.1 - 7.8 6.1 6.3 2.5 7.6 2.9 2.0 2 1 0 2 2 2 0 zinc-ribbon domain UreF PF01730.16 KZN86566.1 - 4.4e-22 79.1 0.4 7.6e-22 78.3 0.4 1.3 1 0 0 1 1 1 1 UreF Med9 PF07544.13 KZN86566.1 - 0.18 11.9 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Sugarporin_N PF11471.8 KZN86566.1 - 3.1 7.8 5.7 1.8 8.5 2.2 2.4 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension ABC1 PF03109.16 KZN86567.1 - 1.4e-33 115.6 0.0 3.5e-33 114.3 0.0 1.8 1 0 0 1 1 1 1 ABC1 family ERG4_ERG24 PF01222.17 KZN86568.1 - 1.3e-139 465.7 3.5 1.5e-139 465.5 3.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KZN86568.1 - 0.00024 20.7 0.1 0.00024 20.7 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) OTT_1508_deam PF14441.6 KZN86569.1 - 3.7e-17 62.1 0.5 1e-16 60.7 0.5 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase Peptidase_S64 PF08192.11 KZN86570.1 - 0.00046 18.8 0.2 0.044 12.3 0.1 2.1 2 0 0 2 2 2 2 Peptidase family S64 Peptidase_S32 PF05579.13 KZN86570.1 - 0.014 14.6 0.1 0.022 14.0 0.1 1.2 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 BRX_N PF13713.6 KZN86570.1 - 0.32 10.8 1.4 0.62 9.9 1.4 1.4 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain DUF3716 PF12511.8 KZN86571.1 - 0.00042 20.3 2.4 0.001 19.1 2.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Tho2 PF11262.8 KZN86573.1 - 0.017 14.3 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Sipho_Gp157 PF05565.11 KZN86573.1 - 0.022 14.8 0.4 0.035 14.1 0.4 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 Myosin_tail_1 PF01576.19 KZN86573.1 - 0.034 12.0 1.5 0.047 11.5 1.5 1.0 1 0 0 1 1 1 0 Myosin tail KLRAQ PF10205.9 KZN86573.1 - 0.081 13.2 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein HALZ PF02183.18 KZN86573.1 - 0.085 13.1 2.2 0.25 11.6 0.7 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper Tmemb_cc2 PF10267.9 KZN86573.1 - 0.095 11.8 0.4 0.15 11.1 0.4 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Fez1 PF06818.15 KZN86573.1 - 0.11 12.9 0.7 0.19 12.2 0.7 1.2 1 0 0 1 1 1 0 Fez1 DUF1664 PF07889.12 KZN86573.1 - 0.16 12.0 0.3 0.91 9.6 0.2 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Occludin_ELL PF07303.13 KZN86573.1 - 0.34 11.7 1.1 0.59 10.9 1.1 1.3 1 0 0 1 1 1 0 Occludin homology domain TMCO5 PF14992.6 KZN86573.1 - 0.61 9.6 3.6 0.98 8.9 3.6 1.2 1 0 0 1 1 1 0 TMCO5 family Mannosyl_trans3 PF11051.8 KZN86574.1 - 1.7e-64 217.8 0.0 7.5e-39 133.7 0.0 2.1 1 1 1 2 2 2 2 Mannosyltransferase putative Sacchrp_dh_NADP PF03435.18 KZN86575.1 - 0.066 13.5 0.7 0.1 12.8 0.0 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Ribosomal_60s PF00428.19 KZN86575.1 - 0.44 11.2 0.1 0.44 11.2 0.1 3.6 2 2 0 2 2 2 0 60s Acidic ribosomal protein Pes-10 PF07149.11 KZN86575.1 - 0.5 9.4 7.8 2.2 7.3 0.0 2.5 2 0 0 2 2 2 0 Pes-10 DNA_pol_phi PF04931.13 KZN86575.1 - 5.5 5.0 10.3 9 4.3 10.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 KZN86575.1 - 9.5 5.3 8.7 2.9 7.0 5.2 1.8 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Fungal_trans_2 PF11951.8 KZN86576.1 - 2.3e-48 164.9 0.7 2.8e-48 164.7 0.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_1_2 PF00155.21 KZN86577.1 - 2.8e-41 141.9 0.0 4e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KZN86577.1 - 3.7e-07 29.7 0.0 5.6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KZN86577.1 - 9.6e-06 24.8 0.0 2.1e-05 23.7 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KZN86577.1 - 0.00021 19.9 0.0 0.00031 19.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KZN86577.1 - 0.019 14.3 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family AMPK1_CBM PF16561.5 KZN86579.1 - 5e-28 97.2 0.0 8e-28 96.5 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 KZN86579.1 - 2.4e-25 88.6 1.0 1e-24 86.6 1.0 2.1 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM_48 PF02922.18 KZN86579.1 - 0.092 13.1 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Peptidase_M22 PF00814.25 KZN86580.1 - 5.7e-86 288.6 0.0 7e-86 288.3 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 KZN86580.1 - 0.016 14.9 0.0 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus SET PF00856.28 KZN86581.1 - 1.7e-21 77.4 0.0 4.7e-21 75.9 0.0 1.8 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 KZN86581.1 - 6.9e-10 39.7 3.3 7.2e-10 39.6 0.5 2.1 1 1 1 2 2 2 1 Rubisco LSMT substrate-binding EPL1 PF10513.9 KZN86582.1 - 1.8e-23 83.7 0.4 1.8e-23 83.7 0.4 3.1 2 1 0 2 2 2 1 Enhancer of polycomb-like EF-hand_1 PF00036.32 KZN86583.1 - 5e-26 88.3 13.0 1.9e-07 30.2 1.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KZN86583.1 - 1.1e-20 73.8 12.1 1.2e-12 48.0 1.8 2.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KZN86583.1 - 6.1e-20 69.4 7.1 5.9e-05 22.7 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KZN86583.1 - 1.8e-17 61.9 10.8 8.7e-06 25.0 0.8 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KZN86583.1 - 2.4e-12 46.5 9.4 0.00017 21.4 0.4 4.0 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KZN86583.1 - 3.1e-07 30.7 0.0 0.0021 18.3 0.1 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KZN86583.1 - 0.00034 20.5 7.8 0.27 11.2 0.7 3.8 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KZN86583.1 - 0.099 13.0 0.2 1.5 9.2 0.1 2.6 3 0 0 3 3 3 0 EF-hand domain PMBR PF09373.10 KZN86583.1 - 0.16 12.2 0.0 3 8.2 0.0 2.4 2 0 0 2 2 2 0 Pseudomurein-binding repeat Ribosomal_S9 PF00380.19 KZN86585.1 - 1.1e-38 132.4 0.5 1.8e-38 131.8 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 PDEase_I_N PF08499.12 KZN86585.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal EF1G PF00647.19 KZN86586.1 - 2.8e-41 139.9 0.3 5.2e-41 139.0 0.3 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 KZN86586.1 - 3e-14 53.0 0.1 6.2e-14 52.0 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KZN86586.1 - 2.5e-13 50.1 0.1 1.8e-12 47.4 0.0 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KZN86586.1 - 3.5e-09 36.6 0.1 3.5e-09 36.6 0.1 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KZN86586.1 - 3.5e-05 24.1 0.0 7.8e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KZN86586.1 - 0.00044 20.4 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KZN86586.1 - 0.034 14.5 0.0 0.12 12.7 0.0 2.0 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Ribosomal_60s PF00428.19 KZN86586.1 - 4.6 7.9 15.1 5 7.8 11.7 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein NIF PF03031.18 KZN86588.1 - 1.8e-25 89.5 0.1 2.8e-24 85.7 0.1 2.2 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase RR_TM4-6 PF06459.12 KZN86588.1 - 1.3 8.8 7.0 2.2 8.0 7.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RRP36 PF06102.12 KZN86589.1 - 1.1e-46 158.8 24.0 1.1e-46 158.8 24.0 2.1 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 ALMT PF11744.8 KZN86589.1 - 1.2 7.9 17.5 0.43 9.4 7.8 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter RNA_pol_L_2 PF13656.6 KZN86591.1 - 1.2e-32 111.4 0.0 1.6e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KZN86591.1 - 2.5e-14 52.5 0.0 3.6e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_LYR_2 PF13233.6 KZN86592.1 - 1.9e-06 28.5 0.1 2.6e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KZN86592.1 - 2.5e-05 24.3 0.0 4.4e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) IKKbetaNEMObind PF12179.8 KZN86592.1 - 0.078 13.0 0.0 0.78 9.8 0.0 2.2 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain Abhydrolase_1 PF00561.20 KZN86594.1 - 1.6e-10 41.1 0.0 5.4e-10 39.4 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KZN86594.1 - 7.9e-08 31.9 0.0 3.8e-07 29.6 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KZN86594.1 - 0.001 19.7 0.0 0.0036 18.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cohesin_load PF10345.9 KZN86595.1 - 6.2e-176 586.4 2.0 7.2e-176 586.1 2.0 1.0 1 0 0 1 1 1 1 Cohesin loading factor TPR_12 PF13424.6 KZN86595.1 - 0.3 11.4 0.1 0.3 11.4 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 KZN86595.1 - 2 9.3 4.1 56 4.8 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Histone PF00125.24 KZN86596.1 - 1.7e-41 141.6 0.9 2.8e-41 140.9 0.9 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KZN86596.1 - 4.6e-05 23.5 0.3 0.0001 22.4 0.0 1.7 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KZN86596.1 - 0.00084 19.7 0.1 0.0015 18.8 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KZN86596.1 - 0.026 14.8 0.5 0.026 14.8 0.5 1.9 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KZN86596.1 - 0.08 13.0 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DER1 PF04511.15 KZN86597.1 - 3.5e-49 167.4 5.9 4e-49 167.2 5.9 1.0 1 0 0 1 1 1 1 Der1-like family DUF4395 PF14340.6 KZN86597.1 - 3.3 8.0 8.1 1.8 8.9 4.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4395) Gly_transf_sug PF04488.15 KZN86598.1 - 1.5e-19 70.5 0.0 2.6e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Ufm1 PF03671.14 KZN86599.1 - 0.072 13.2 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin fold modifier 1 protein IGPD PF00475.18 KZN86600.1 - 4.9e-56 189.0 0.6 7.1e-56 188.5 0.6 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Arena_RNA_pol PF06317.11 KZN86600.1 - 0.37 7.9 0.0 0.48 7.5 0.0 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase Pet127 PF08634.10 KZN86602.1 - 5.9e-118 393.3 0.7 9e-118 392.6 0.7 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 TSP9 PF11493.8 KZN86602.1 - 0.022 15.4 0.4 4.1 8.1 0.1 2.8 2 0 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 GARS_A PF01071.19 KZN86603.1 - 2.9e-81 271.9 0.0 4.5e-81 271.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 KZN86603.1 - 4.7e-34 117.8 0.0 9.6e-34 116.8 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 KZN86603.1 - 9.1e-34 116.1 0.0 3e-33 114.5 0.0 2.0 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 KZN86603.1 - 2e-26 92.1 0.2 5.1e-26 90.8 0.2 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KZN86603.1 - 7.9e-15 55.3 1.5 3.2e-14 53.3 1.5 2.1 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_3 PF02655.14 KZN86603.1 - 0.00019 21.5 0.1 0.00062 19.8 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.22 KZN86603.1 - 0.00042 19.9 0.0 0.00071 19.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KZN86603.1 - 0.00053 19.5 0.9 0.00074 19.1 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_2 PF08442.10 KZN86603.1 - 0.00062 19.4 0.0 0.0027 17.3 0.0 2.0 3 0 0 3 3 3 1 ATP-grasp domain ATP-grasp_4 PF13535.6 KZN86603.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.6 KZN86603.1 - 0.046 13.0 0.0 0.24 10.6 0.0 2.0 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Actin PF00022.19 KZN86604.1 - 2.3e-149 497.4 0.0 9.1e-149 495.5 0.0 1.7 1 1 0 1 1 1 1 Actin Fes1 PF08609.10 KZN86605.1 - 1.5e-31 109.1 2.1 3.5e-31 107.9 0.4 2.1 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_EZ PF13513.6 KZN86605.1 - 5.8e-08 33.1 0.3 1.1e-05 25.8 0.1 2.7 2 1 1 3 3 3 2 HEAT-like repeat Arm PF00514.23 KZN86605.1 - 1.8e-07 31.0 0.1 0.0015 18.5 0.0 2.4 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KZN86605.1 - 5.6e-07 29.9 0.3 1.9e-06 28.2 0.3 1.9 1 1 0 1 1 1 1 HEAT repeats HEAT PF02985.22 KZN86605.1 - 2.5e-05 24.2 0.0 0.0092 16.2 0.0 2.6 2 0 0 2 2 2 1 HEAT repeat V-ATPase_H_C PF11698.8 KZN86605.1 - 0.0013 18.9 0.2 0.084 13.0 0.0 1.9 1 1 1 2 2 2 2 V-ATPase subunit H SIL1 PF16782.5 KZN86605.1 - 0.0047 16.2 0.2 0.54 9.4 0.1 2.1 1 1 1 2 2 2 2 Nucleotide exchange factor SIL1 Atx10homo_assoc PF09759.9 KZN86605.1 - 0.016 15.2 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain Adaptin_N PF01602.20 KZN86605.1 - 0.027 13.0 0.0 0.039 12.5 0.0 1.2 1 0 0 1 1 1 0 Adaptin N terminal region V-ATPase_H_N PF03224.14 KZN86605.1 - 0.099 11.9 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 V-ATPase subunit H CTNNBL PF08216.11 KZN86605.1 - 0.16 12.2 0.4 1.9 8.7 0.2 2.2 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear UPF0220 PF05255.11 KZN86606.1 - 3.6e-71 238.1 2.6 4.2e-71 237.9 2.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF998 PF06197.13 KZN86606.1 - 1.2e-05 25.0 5.1 1.4e-05 24.8 5.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF998) ATP1G1_PLM_MAT8 PF02038.16 KZN86606.1 - 0.0072 15.7 0.7 0.015 14.7 0.1 1.8 2 0 0 2 2 2 1 ATP1G1/PLM/MAT8 family Sld7_C PF18596.1 KZN86607.1 - 1.8e-16 60.1 0.0 3.2e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Sld7 C-terminal domain Vps55 PF04133.14 KZN86608.1 - 1.4e-45 154.0 6.5 1.6e-45 153.9 6.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF4231 PF14015.6 KZN86608.1 - 0.22 12.0 1.1 4.4 7.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF4349 PF14257.6 KZN86608.1 - 0.25 10.7 0.0 0.25 10.7 0.0 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4349) Proteasome PF00227.26 KZN86609.1 - 2.8e-49 167.2 0.1 3.5e-49 166.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KZN86609.1 - 1.3e-12 47.2 0.4 2e-12 46.6 0.4 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Lysine_decarbox PF03641.14 KZN86610.1 - 7.3e-28 97.3 0.0 1.3e-27 96.5 0.0 1.4 1 1 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KZN86610.1 - 0.0093 15.6 2.6 0.013 15.1 0.4 2.0 2 0 0 2 2 2 1 SLOG cluster4 family DAGK_cat PF00781.24 KZN86610.1 - 0.12 12.0 1.8 7.6 6.2 0.1 2.8 2 1 0 3 3 3 0 Diacylglycerol kinase catalytic domain Med6 PF04934.14 KZN86611.1 - 1e-38 132.1 0.1 1.4e-38 131.7 0.1 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component Chorismate_bind PF00425.18 KZN86612.1 - 1.4e-65 221.4 0.0 7.7e-63 212.5 0.0 3.0 2 1 0 2 2 2 1 chorismate binding enzyme GATase PF00117.28 KZN86612.1 - 2.3e-30 105.8 0.0 3.8e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KZN86612.1 - 1.4e-09 38.3 0.0 4.2e-09 36.7 0.0 1.9 1 1 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KZN86612.1 - 0.00027 20.8 0.1 0.00072 19.4 0.1 1.7 1 1 0 1 1 1 1 Peptidase C26 DUF3684 PF12449.8 KZN86613.1 - 0 1425.3 0.0 0 1425.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 KZN86613.1 - 0.00015 21.6 0.0 0.00046 20.0 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WLM PF08325.10 KZN86613.1 - 2.7 8.0 6.1 0.47 10.5 0.4 2.2 2 0 0 2 2 2 0 WLM domain TRAPPC9-Trs120 PF08626.11 KZN86614.1 - 0 1505.0 0.0 0 1504.8 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.6 KZN86614.1 - 0.09 13.1 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Aldedh PF00171.22 KZN86615.1 - 1e-130 436.4 0.0 1.2e-130 436.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3430 PF11912.8 KZN86617.1 - 0.0026 17.8 0.2 0.0031 17.6 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Sugar_tr PF00083.24 KZN86619.1 - 1.4e-92 310.9 21.5 1.7e-92 310.6 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN86619.1 - 1.3e-24 86.8 25.7 1.3e-24 86.8 25.7 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KZN86619.1 - 7.4e-07 28.0 4.4 7.4e-07 28.0 4.4 1.9 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) DUF3021 PF11457.8 KZN86619.1 - 0.0066 16.8 3.1 0.0066 16.8 3.1 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF3021) AAL_decarboxy PF03306.13 KZN86620.1 - 9.3e-72 240.9 0.3 1.1e-71 240.7 0.3 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase TPP_enzyme_N PF02776.18 KZN86621.1 - 9.4e-51 171.8 0.1 2.1e-50 170.7 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KZN86621.1 - 2.9e-40 137.6 0.0 1.7e-38 131.8 0.0 2.7 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KZN86621.1 - 1.3e-33 115.6 0.0 2.5e-33 114.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Glyco_hydro_32N PF00251.20 KZN86622.1 - 1.5e-43 149.5 0.4 8.2e-43 147.1 0.4 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KZN86622.1 - 6e-31 107.6 0.0 9.6e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 KZN86622.1 - 0.0053 16.8 0.0 0.01 15.9 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4975) BNR PF02012.20 KZN86622.1 - 0.0083 16.0 0.2 0.061 13.3 0.2 2.6 1 0 0 1 1 1 1 BNR/Asp-box repeat Nuc_deoxyri_tr2 PF15891.5 KZN86623.1 - 4.7e-37 126.6 0.0 6.1e-37 126.2 0.0 1.2 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like Ribosomal_L7Ae PF01248.26 KZN86624.1 - 4.2e-26 90.5 0.0 5.1e-26 90.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KZN86624.1 - 0.00024 21.2 0.0 0.00025 21.1 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 KZN86624.1 - 0.0052 16.6 0.0 0.008 16.0 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain Tim17 PF02466.19 KZN86625.1 - 4.1e-31 107.6 7.0 5.1e-31 107.3 7.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HATPase_c_4 PF13749.6 KZN86625.1 - 0.06 13.5 0.0 0.1 12.8 0.0 1.3 1 1 0 1 1 1 0 Putative ATP-dependent DNA helicase recG C-terminal zf-CCHC PF00098.23 KZN86626.1 - 0.0017 18.3 1.4 0.004 17.2 0.2 2.0 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.17 KZN86626.1 - 0.023 15.0 0.1 0.24 11.7 0.0 2.4 2 1 1 3 3 3 0 Retrotransposon gag protein zf-CCHC_2 PF13696.6 KZN86626.1 - 0.78 9.6 3.0 2.5 8.0 0.2 2.3 2 0 0 2 2 2 0 Zinc knuckle Peptidase_S7 PF00949.21 KZN86628.1 - 0.0026 17.6 0.2 0.027 14.3 0.2 2.4 2 1 0 2 2 2 1 Peptidase S7, Flavivirus NS3 serine protease Trypsin PF00089.26 KZN86628.1 - 0.038 13.8 0.0 0.2 11.5 0.1 1.9 2 0 0 2 2 2 0 Trypsin RraA-like PF03737.15 KZN86629.1 - 5.2e-14 52.6 1.8 6.7e-14 52.3 1.8 1.1 1 0 0 1 1 1 1 Aldolase/RraA SelP_N PF04592.14 KZN86629.1 - 0.14 11.6 0.1 0.24 10.8 0.1 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ank_4 PF13637.6 KZN86631.1 - 6.4e-19 68.1 1.1 0.00014 22.3 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KZN86631.1 - 7.1e-18 65.0 4.4 1e-08 35.6 0.0 5.4 4 3 2 6 6 6 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KZN86631.1 - 1.7e-14 53.7 3.3 4e-07 30.2 0.0 5.6 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 KZN86631.1 - 2.7e-12 46.5 1.6 0.0083 16.5 0.0 6.0 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 KZN86631.1 - 4.1e-10 39.0 9.6 0.013 16.0 0.0 7.5 8 1 1 9 9 9 2 Ankyrin repeat DUF3447 PF11929.8 KZN86631.1 - 0.031 14.2 0.1 0.78 9.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) Ank_2 PF12796.7 KZN86632.1 - 7.2e-27 93.8 0.2 1.1e-09 38.8 0.0 2.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KZN86632.1 - 6.9e-19 67.4 0.1 0.00079 19.8 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KZN86632.1 - 2.7e-16 58.0 0.1 0.00044 20.5 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 KZN86632.1 - 2.3e-13 50.0 1.9 9e-06 25.9 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KZN86632.1 - 1.2e-12 48.0 0.6 0.00088 19.8 0.0 4.6 2 1 3 5 5 5 3 Ankyrin repeats (many copies) CorA PF01544.18 KZN86633.1 - 5.5e-07 29.2 0.0 8.4e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 KZN86633.1 - 0.016 14.0 0.2 0.022 13.5 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) p450 PF00067.22 KZN86634.1 - 1.1e-72 245.3 0.0 1.4e-72 245.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Bin3 PF06859.12 KZN86635.1 - 3.5e-32 111.3 0.0 4.9e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_23 PF13489.6 KZN86635.1 - 5.1e-12 45.9 0.0 6.8e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN86635.1 - 2.5e-11 43.6 0.0 3.2e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN86635.1 - 3.5e-09 37.2 0.0 6.4e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN86635.1 - 1.9e-08 34.8 0.0 3.6e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN86635.1 - 1.2e-07 32.4 0.0 2e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KZN86635.1 - 0.0001 21.9 0.0 0.00041 19.9 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 KZN86635.1 - 0.0016 17.9 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 KZN86635.1 - 0.019 14.9 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KZN86635.1 - 0.079 12.6 0.0 2.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Glyco_hydro_16 PF00722.21 KZN86636.1 - 3.9e-10 39.5 0.0 1.7e-09 37.4 0.0 1.8 1 1 0 2 2 2 1 Glycosyl hydrolases family 16 p450 PF00067.22 KZN86637.1 - 6.6e-67 226.2 0.0 8.8e-67 225.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF5486 PF17588.2 KZN86637.1 - 0.048 13.6 0.0 0.48 10.3 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5486) Pkinase_fungal PF17667.1 KZN86637.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Fungal_trans PF04082.18 KZN86638.1 - 1.9e-08 33.6 0.0 4.5e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN86638.1 - 1.4e-06 28.3 12.7 2.4e-06 27.6 12.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.12 KZN86638.1 - 0.072 13.0 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 NinF PF05810.12 KZN86638.1 - 0.43 10.5 2.0 0.95 9.4 2.0 1.5 1 0 0 1 1 1 0 NinF protein RRM_1 PF00076.22 KZN86639.1 - 1.2e-34 117.9 0.0 1.4e-19 69.7 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KZN86639.1 - 0.013 15.6 0.0 2.3 8.4 0.0 2.7 2 2 0 2 2 2 0 RNA recognition motif RRM_8 PF11835.8 KZN86639.1 - 0.04 14.1 0.0 0.08 13.2 0.0 1.5 1 0 0 1 1 1 0 RRM-like domain SET_assoc PF11767.8 KZN86639.1 - 0.11 12.2 0.0 0.4 10.4 0.0 1.9 1 1 0 1 1 1 0 Histone lysine methyltransferase SET associated DUF3445 PF11927.8 KZN86640.1 - 3.9e-76 255.6 0.2 4.7e-76 255.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Amidohydro_1 PF01979.20 KZN86641.1 - 9.8e-31 107.3 0.0 1.5e-30 106.7 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KZN86641.1 - 2.1e-11 44.0 0.0 7.7e-07 28.9 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family ubiquitin PF00240.23 KZN86641.1 - 0.21 11.4 0.0 0.43 10.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family AA_permease_2 PF13520.6 KZN86642.1 - 6e-39 134.1 48.3 7.6e-39 133.7 48.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN86642.1 - 6.5e-25 87.7 46.2 8.7e-25 87.2 46.2 1.0 1 0 0 1 1 1 1 Amino acid permease Phenol_monoox PF04663.12 KZN86642.1 - 0.083 13.0 4.1 38 4.5 0.0 4.0 4 0 0 4 4 4 0 Phenol hydroxylase conserved region Ribonuc_L-PSP PF01042.21 KZN86643.1 - 8.7e-19 67.7 0.0 1e-18 67.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Aldedh PF00171.22 KZN86644.1 - 2.1e-175 583.7 0.1 2.4e-175 583.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TPR_2 PF07719.17 KZN86645.1 - 8.1e-22 75.5 3.4 1.7e-07 30.8 0.1 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 KZN86645.1 - 1.2e-21 75.5 2.8 2.8e-08 33.2 0.1 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 KZN86645.1 - 6.4e-18 64.2 2.8 5.2e-09 35.7 0.1 5.0 4 1 1 5 5 5 3 TPR repeat TPR_16 PF13432.6 KZN86645.1 - 1.8e-17 63.7 3.1 1.2e-05 25.8 0.0 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KZN86645.1 - 5.3e-16 57.9 1.3 8e-05 23.1 0.0 5.7 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KZN86645.1 - 9.5e-15 54.9 2.9 0.00047 20.6 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KZN86645.1 - 2.5e-13 49.4 1.6 0.0076 16.6 0.1 4.9 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 KZN86645.1 - 3.7e-13 48.5 0.7 2.7e-06 27.1 0.0 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KZN86645.1 - 1.4e-10 40.4 2.6 0.0068 16.4 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.6 KZN86645.1 - 1.7e-10 41.1 0.3 0.007 16.7 0.0 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KZN86645.1 - 8.6e-10 38.8 3.9 2.2e-06 27.9 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KZN86645.1 - 1.4e-09 37.9 2.8 0.0015 18.7 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KZN86645.1 - 3.9e-06 27.2 1.2 1.2 9.9 0.0 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KZN86645.1 - 2.1e-05 24.6 3.2 0.00044 20.4 0.5 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KZN86645.1 - 0.00012 21.4 0.5 0.26 10.5 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.12 KZN86645.1 - 0.00044 20.2 0.1 0.15 12.1 0.0 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat MIT PF04212.18 KZN86645.1 - 0.00083 19.4 0.4 4.8 7.3 0.1 4.1 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 KZN86645.1 - 0.0064 16.3 4.3 0.063 13.2 0.9 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF1641 PF07849.11 KZN86645.1 - 0.075 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) TOM20_plant PF06552.12 KZN86645.1 - 0.13 12.0 0.1 4.1 7.1 0.0 2.9 3 1 1 4 4 3 0 Plant specific mitochondrial import receptor subunit TOM20 DUF4192 PF13830.6 KZN86645.1 - 0.64 10.0 6.8 4 7.4 6.8 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4192) Amidase PF01425.21 KZN86646.1 - 1.2e-83 281.6 0.0 8.3e-83 278.8 0.0 1.9 1 1 0 1 1 1 1 Amidase Sterol_MT_C PF08498.10 KZN86646.1 - 0.0072 16.6 0.0 0.041 14.2 0.0 2.2 2 0 0 2 2 2 1 Sterol methyltransferase C-terminal LIP PF03583.14 KZN86647.1 - 4.7e-10 39.3 0.5 1.2e-05 24.8 0.0 2.1 2 0 0 2 2 2 2 Secretory lipase Abhydrolase_6 PF12697.7 KZN86647.1 - 5.7e-06 27.1 4.4 8.8e-06 26.5 4.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KZN86647.1 - 6.3e-06 25.6 0.8 4.4e-05 22.9 0.8 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KZN86647.1 - 0.022 14.3 0.5 0.35 10.3 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KZN86647.1 - 0.041 13.5 0.7 0.084 12.5 0.3 1.8 2 1 0 2 2 2 0 alpha/beta hydrolase fold Zn_clus PF00172.18 KZN86648.1 - 5.4e-07 29.6 10.2 1.4e-06 28.3 10.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA_bind_3 PF17176.4 KZN86648.1 - 0.0083 16.4 0.4 0.047 14.0 0.1 2.4 2 0 0 2 2 2 1 tRNA-binding domain Herpes_UL92 PF03048.14 KZN86648.1 - 0.15 11.8 1.6 0.27 11.0 1.6 1.4 1 0 0 1 1 1 0 UL92 family Abhydrolase_2 PF02230.16 KZN86649.1 - 0.00055 19.8 0.0 0.0008 19.3 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.20 KZN86649.1 - 0.0008 19.1 0.1 0.0019 17.9 0.1 1.5 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 KZN86649.1 - 0.0037 16.8 0.1 0.0073 15.8 0.1 1.5 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KZN86649.1 - 0.11 12.0 0.1 0.35 10.3 0.1 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Glyco_hydro_61 PF03443.14 KZN86650.1 - 2e-49 168.3 0.1 2.9e-49 167.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.16 KZN86651.1 - 3e-43 148.1 31.1 3e-43 148.1 31.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN86651.1 - 4.5e-10 39.0 8.6 4.5e-10 39.0 8.6 2.8 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KZN86651.1 - 1.1e-06 27.4 3.4 1.1e-06 27.4 3.4 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF5536 PF17688.1 KZN86651.1 - 0.0044 16.9 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5536) Lactamase_B_2 PF12706.7 KZN86652.1 - 8.1e-14 51.6 0.0 1.9e-13 50.4 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KZN86652.1 - 2.3e-09 37.3 0.0 3.2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KZN86652.1 - 0.054 13.5 0.1 7.5 6.5 0.0 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily TPR_2 PF07719.17 KZN86653.1 - 1.3e-09 37.4 9.6 0.013 15.6 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KZN86653.1 - 7.8e-07 28.7 1.7 0.44 10.5 0.0 5.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KZN86653.1 - 1.1e-05 25.3 2.7 5 7.6 0.1 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KZN86653.1 - 1.8e-05 24.4 1.9 0.11 12.6 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 KZN86653.1 - 2.9e-05 24.5 5.9 14 6.9 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 KZN86653.1 - 6e-05 23.6 15.5 4.6 8.0 0.0 7.0 6 2 2 8 8 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 KZN86653.1 - 0.00013 22.2 8.7 0.81 10.0 0.3 5.6 4 2 1 5 5 4 3 Tetratricopeptide repeat TPR_4 PF07721.14 KZN86653.1 - 0.00041 20.7 6.0 0.12 13.1 0.1 4.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KZN86653.1 - 0.0016 18.3 4.2 0.33 10.9 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KZN86653.1 - 0.0032 18.0 3.6 0.94 10.0 0.0 5.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KZN86653.1 - 0.031 13.9 0.7 45 3.8 0.0 5.0 6 0 0 6 6 6 0 TPR repeat TPR_MalT PF17874.1 KZN86653.1 - 0.033 13.6 0.2 0.16 11.4 0.0 2.2 3 0 0 3 3 3 0 MalT-like TPR region TPR_9 PF13371.6 KZN86653.1 - 0.06 13.5 0.2 1.2 9.3 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Sel1 PF08238.12 KZN86653.1 - 0.24 12.1 5.2 22 5.9 0.0 4.3 4 0 0 4 4 4 0 Sel1 repeat Lactamase_B_2 PF12706.7 KZN86654.1 - 2.2e-12 46.9 0.1 4e-12 46.1 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KZN86654.1 - 1.7e-11 44.3 0.0 2.4e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain FA_hydroxylase PF04116.13 KZN86655.1 - 0.00041 20.7 17.5 0.0024 18.2 15.4 2.4 1 1 1 2 2 2 2 Fatty acid hydroxylase superfamily DUF3669 PF12417.8 KZN86656.1 - 1.2e-15 57.5 0.0 4.9e-15 55.5 0.0 2.1 2 0 0 2 2 2 1 Zinc finger protein Methyltransf_28 PF02636.17 KZN86659.1 - 1.8e-39 136.0 0.0 2.5e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pathogen_betaC1 PF09593.10 KZN86659.1 - 0.14 12.1 0.4 11 6.0 0.0 2.4 2 0 0 2 2 2 0 Beta-satellite pathogenicity beta C1 protein PRMT5 PF05185.16 KZN86659.1 - 0.18 11.6 0.0 0.42 10.4 0.0 1.5 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase PRT_C PF08372.10 KZN86659.1 - 0.67 9.7 3.8 0.27 11.0 0.7 1.9 3 0 0 3 3 3 0 Plant phosphoribosyltransferase C-terminal PALP PF00291.25 KZN86660.1 - 4.9e-60 203.4 0.4 6.2e-60 203.1 0.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Scm3 PF10384.9 KZN86661.1 - 2.4e-21 75.2 0.0 5.2e-21 74.1 0.0 1.6 1 0 0 1 1 1 1 Centromere protein Scm3 APG6 PF04111.12 KZN86662.1 - 3.7e-73 245.3 0.0 5.4e-73 244.8 0.0 1.2 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 KZN86662.1 - 6.5e-39 133.5 7.5 1.3e-38 132.5 7.5 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region KASH_CCD PF14662.6 KZN86662.1 - 0.021 14.7 5.0 0.036 13.9 5.0 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH HIP1_clath_bdg PF16515.5 KZN86662.1 - 0.17 12.5 4.1 0.24 12.0 0.9 2.4 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Snapin_Pallidin PF14712.6 KZN86662.1 - 0.32 11.5 2.9 0.38 11.2 0.5 2.1 2 0 0 2 2 2 0 Snapin/Pallidin DUF5595 PF18077.1 KZN86662.1 - 0.74 9.9 2.6 3.1 7.9 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) Jnk-SapK_ap_N PF09744.9 KZN86662.1 - 8.2 6.6 10.0 19 5.5 10.0 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Clr5 PF14420.6 KZN86663.1 - 9.5e-16 57.8 3.9 2.1e-15 56.6 3.9 1.6 1 0 0 1 1 1 1 Clr5 domain Pex14_N PF04695.13 KZN86663.1 - 0.018 15.7 3.7 0.018 15.7 3.7 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peroxin-13_N PF04088.13 KZN86664.1 - 1.8e-52 177.4 0.1 2.6e-52 176.9 0.1 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 KZN86664.1 - 7.6e-10 38.3 0.0 1.6e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KZN86664.1 - 1.2e-08 34.4 0.0 2.1e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KZN86664.1 - 5.3e-06 26.2 0.1 8.6e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain OAD_gamma PF04277.13 KZN86664.1 - 0.12 13.0 0.0 0.87 10.2 0.0 2.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain hSH3 PF14603.6 KZN86664.1 - 0.16 12.4 0.0 0.29 11.6 0.0 1.3 1 0 0 1 1 1 0 Helically-extended SH3 domain ERO1 PF04137.15 KZN86665.1 - 1.8e-133 445.1 0.0 2.3e-133 444.8 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) p450 PF00067.22 KZN86667.1 - 1.3e-37 129.6 0.0 1.6e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RtcR PF06956.11 KZN86667.1 - 0.01 15.3 0.0 0.099 12.1 0.0 2.3 3 0 0 3 3 3 0 Regulator of RNA terminal phosphate cyclase DUF2015 PF09435.10 KZN86667.1 - 0.054 13.4 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2015) polyprenyl_synt PF00348.17 KZN86668.1 - 2.1e-43 148.2 0.0 3.5e-43 147.5 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase Abhydrolase_6 PF12697.7 KZN86669.1 - 5.8e-22 79.4 5.5 6.7e-22 79.2 5.5 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KZN86669.1 - 0.0038 16.9 0.3 0.0069 16.1 0.3 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold AMP-binding PF00501.28 KZN86670.1 - 1.2e-91 307.4 0.0 1.4e-91 307.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KZN86670.1 - 5e-13 49.8 0.0 1.1e-12 48.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sugar_tr PF00083.24 KZN86671.1 - 5.5e-128 427.6 18.7 6.4e-128 427.4 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN86671.1 - 4e-23 81.9 25.1 4e-23 81.9 25.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GDP_Man_Dehyd PF16363.5 KZN86671.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase MFS_1 PF07690.16 KZN86672.1 - 7.3e-31 107.4 37.4 1.2e-30 106.6 37.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1240 PF06836.12 KZN86672.1 - 10 6.8 9.4 2 9.0 0.2 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1240) Fungal_trans_2 PF11951.8 KZN86673.1 - 8.4e-06 24.8 6.4 7e-05 21.8 0.5 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain EPTP PF03736.17 KZN86673.1 - 0.018 15.0 0.0 0.047 13.7 0.0 1.6 1 0 0 1 1 1 0 EPTP domain COesterase PF00135.28 KZN86674.1 - 1.3e-72 245.3 0.0 1.8e-72 244.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KZN86674.1 - 3.6e-08 33.5 0.0 0.0018 18.1 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold AMP-binding PF00501.28 KZN86677.1 - 4.1e-29 101.4 0.1 7.8e-29 100.5 0.1 1.3 2 0 0 2 2 2 1 AMP-binding enzyme CcmD PF04995.14 KZN86678.1 - 0.12 12.5 1.1 0.38 10.9 1.1 1.9 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Fungal_trans PF04082.18 KZN86679.1 - 3.2e-13 49.3 0.2 7.5e-13 48.1 0.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain DAO PF01266.24 KZN86680.1 - 9.2e-46 157.0 0.1 1e-45 156.9 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KZN86680.1 - 0.013 15.4 0.4 0.021 14.7 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KZN86680.1 - 0.032 13.5 0.0 0.032 13.5 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KZN86680.1 - 0.046 13.0 0.0 0.063 12.5 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase GIDA PF01134.22 KZN86680.1 - 0.059 12.4 0.2 0.11 11.6 0.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 KZN86680.1 - 0.083 11.6 2.3 3.8 6.1 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 KZN86680.1 - 0.16 11.3 2.0 0.25 10.6 2.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KZN86680.1 - 0.19 11.1 0.0 0.34 10.3 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pkinase PF00069.25 KZN86683.1 - 9e-31 107.2 0.0 3.3e-15 56.2 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KZN86683.1 - 1.7e-09 37.4 0.0 7.9e-05 22.1 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 KZN86683.1 - 0.23 10.8 0.0 0.39 10.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.16 KZN86684.1 - 6.8e-39 133.8 29.2 6.8e-39 133.8 29.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN86684.1 - 3.3e-12 46.0 8.1 3.3e-12 46.0 8.1 2.1 2 2 0 2 2 2 1 Sugar (and other) transporter DUF2140 PF09911.9 KZN86684.1 - 0.085 12.4 0.2 0.18 11.4 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Methyltransf_23 PF13489.6 KZN86687.1 - 5.8e-16 58.8 0.1 7.5e-16 58.4 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN86687.1 - 9.1e-13 48.3 0.0 1.3e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN86687.1 - 5.7e-12 46.2 0.2 1.2e-11 45.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN86687.1 - 7.9e-12 45.7 0.0 1.6e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN86687.1 - 8.3e-11 42.5 0.0 1.7e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KZN86687.1 - 1.8e-06 27.4 0.0 2.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.12 KZN86687.1 - 0.0036 16.4 0.0 0.0051 15.9 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_15 PF09445.10 KZN86687.1 - 0.0066 16.0 0.0 0.0099 15.5 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase tRNA_U5-meth_tr PF05958.11 KZN86687.1 - 0.0097 14.9 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TPMT PF05724.11 KZN86687.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Beta-lactamase PF00144.24 KZN86688.1 - 1.7e-51 175.4 0.0 2.6e-51 174.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KZN86688.1 - 5.5e-16 58.9 0.0 9.6e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) PAF-AH_p_II PF03403.13 KZN86688.1 - 2.4e-07 29.6 0.0 0.0018 16.9 0.0 2.5 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KZN86688.1 - 0.0034 16.4 0.0 0.0064 15.4 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 KZN86688.1 - 0.076 13.6 0.3 0.23 12.1 0.3 1.9 1 0 0 1 1 1 0 Alpha/beta hydrolase family DNA_pol3_beta PF00712.19 KZN86688.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain ABC_tran PF00005.27 KZN86689.1 - 1.8e-21 77.1 0.0 2.6e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter DUF87 PF01935.17 KZN86689.1 - 0.085 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain DUF3895 PF13034.6 KZN86691.1 - 0.17 11.9 0.1 0.39 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3895) MitoNEET_N PF10660.9 KZN86691.1 - 0.19 11.8 0.3 0.54 10.3 0.0 1.9 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus NTP_transf_5 PF14907.6 KZN86692.1 - 0.083 12.5 0.1 0.15 11.7 0.1 1.6 1 1 0 1 1 1 0 Uncharacterised nucleotidyltransferase AbiEii PF08843.11 KZN86692.1 - 0.084 12.8 0.1 0.17 11.8 0.1 1.5 1 1 0 1 1 1 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system Terpene_synth_C PF03936.16 KZN86693.1 - 8.4e-05 22.0 0.0 0.00012 21.6 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain F-box-like PF12937.7 KZN86694.1 - 0.00023 21.0 0.0 0.0005 19.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like TRAF6_Z2 PF18048.1 KZN86694.1 - 0.062 13.4 0.9 0.11 12.6 0.9 1.4 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 F-box PF00646.33 KZN86694.1 - 0.093 12.6 0.3 0.25 11.3 0.1 1.8 2 0 0 2 2 2 0 F-box domain 3HCDH_N PF02737.18 KZN86694.1 - 0.19 11.6 0.0 0.28 11.0 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3659 PF12396.8 KZN86695.1 - 1.7e-165 537.1 92.4 2.3e-20 72.2 0.4 9.6 9 0 0 9 9 9 9 Protein of unknown function (DUF3659) Apolipoprotein PF01442.18 KZN86695.1 - 0.00033 20.6 15.2 0.00033 20.6 15.2 3.1 3 1 0 3 3 3 1 Apolipoprotein A1/A4/E domain RPW8 PF05659.11 KZN86695.1 - 0.33 10.7 1.7 0.44 10.2 0.4 1.8 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 CDP-OH_P_transf PF01066.21 KZN86696.1 - 1.8e-14 54.2 0.2 1.8e-14 54.2 0.2 3.3 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Peptidase_M1_N PF17900.1 KZN86697.1 - 0.0068 16.6 0.0 4.6 7.4 0.0 2.3 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 KZN86697.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M1 domain LSM PF01423.22 KZN86698.1 - 4.8e-21 74.2 0.1 5.4e-21 74.1 0.1 1.0 1 0 0 1 1 1 1 LSM domain HIP1_clath_bdg PF16515.5 KZN86699.1 - 0.14 12.8 6.3 0.2 12.3 0.3 3.2 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Mitoc_mL59 PF18126.1 KZN86699.1 - 0.16 12.2 3.2 0.12 12.7 0.4 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein mL59 2-Hacid_dh_C PF02826.19 KZN86701.1 - 3.7e-40 137.2 0.5 5.1e-40 136.7 0.5 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KZN86701.1 - 2.8e-09 36.7 0.0 3.6e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 KZN86701.1 - 0.065 13.8 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Gp_dh_N PF00044.24 KZN86701.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ATP_transf PF09830.9 KZN86704.1 - 6.5e-24 83.9 0.0 1.5e-23 82.7 0.0 1.7 1 0 0 1 1 1 1 ATP adenylyltransferase zf-C2H2 PF00096.26 KZN86705.1 - 0.0022 18.4 22.7 0.52 10.9 1.1 5.6 5 0 0 5 5 5 4 Zinc finger, C2H2 type PBP1_TM PF14812.6 KZN86705.1 - 1.4 9.3 3.9 14 6.1 3.2 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FOXP-CC PF16159.5 KZN86705.1 - 2.6 8.8 5.0 24 5.6 0.7 3.3 3 0 0 3 3 3 0 FOXP coiled-coil domain BssC_TutF PF08201.11 KZN86705.1 - 2.7 8.1 5.9 0.31 11.1 0.4 2.4 2 0 0 2 2 2 0 BssC/TutF protein zf-C2H2_4 PF13894.6 KZN86705.1 - 5 8.2 24.3 0.77 10.8 0.7 5.6 5 1 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KZN86705.1 - 6.5 7.2 7.3 22 5.5 0.6 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Glyco_hydro_20 PF00728.22 KZN86706.1 - 3.9e-100 335.7 2.7 4.8e-100 335.4 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KZN86706.1 - 1.1e-22 81.1 0.0 2e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KZN86706.1 - 0.0028 18.4 0.0 0.0057 17.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DHDPS PF00701.22 KZN86707.1 - 1.4e-50 171.7 0.0 1.6e-50 171.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family SAS4 PF15460.6 KZN86708.1 - 1.4e-30 105.3 7.0 3.2e-30 104.1 7.0 1.6 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 PEHE PF15275.6 KZN86708.1 - 0.041 14.5 0.8 0.041 14.5 0.8 3.8 4 1 0 4 4 4 0 PEHE domain DUF669 PF05037.13 KZN86711.1 - 0.04 14.0 0.0 0.06 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF669) APH PF01636.23 KZN86712.1 - 0.002 18.1 0.0 1.6 8.6 0.0 2.1 2 0 0 2 2 2 2 Phosphotransferase enzyme family DUF3807 PF12720.7 KZN86713.1 - 2.2e-37 129.1 8.4 6.5e-37 127.6 8.4 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3807) ANAPC_CDC26 PF10471.9 KZN86713.1 - 5.3 8.0 11.5 4e+02 1.9 11.5 2.7 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 HVSL PF09749.9 KZN86714.1 - 8.6e-84 280.7 0.0 1e-83 280.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein Pkinase PF00069.25 KZN86715.1 - 8.2e-66 222.1 0.0 1.1e-65 221.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN86715.1 - 4.3e-30 104.8 0.0 5.7e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KZN86715.1 - 0.00011 21.6 0.0 0.0003 20.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KZN86715.1 - 0.0011 17.9 0.3 0.14 11.1 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 KZN86715.1 - 0.0026 17.7 0.5 0.0083 16.1 0.1 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KZN86715.1 - 0.049 12.7 0.0 0.08 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 KZN86715.1 - 0.19 11.1 0.1 1.4 8.2 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pal1 PF08316.11 KZN86716.1 - 1.7e-09 38.6 0.2 1.7e-09 38.6 0.2 1.7 2 0 0 2 2 2 1 Pal1 cell morphology protein Peptidase_S10 PF00450.22 KZN86717.1 - 2.8e-76 257.6 0.1 4.3e-76 257.0 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase DUF3425 PF11905.8 KZN86718.1 - 2.8e-12 46.7 6.2 9.4e-12 45.0 6.2 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) Ferritin_2 PF13668.6 KZN86719.1 - 3e-10 40.4 0.0 4.3e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain CUTL PF16557.5 KZN86719.1 - 0.11 12.6 0.1 0.32 11.2 0.1 1.8 1 0 0 1 1 1 0 CUT1-like DNA-binding domain of SATB Glyco_hydro_3_C PF01915.22 KZN86720.1 - 2.2e-55 187.8 0.2 4.2e-55 186.9 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KZN86720.1 - 4.2e-45 154.5 0.0 6.9e-45 153.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KZN86720.1 - 3.4e-29 100.8 0.2 7.6e-29 99.6 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF3372 PF11852.8 KZN86720.1 - 0.12 11.8 0.9 0.46 10.0 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3372) AAA_lid_9 PF17871.1 KZN86721.1 - 0.083 12.8 0.0 0.097 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA lid domain NmrA PF05368.13 KZN86722.1 - 2.8e-05 23.8 0.0 0.00015 21.4 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KZN86722.1 - 0.0042 17.0 0.0 0.013 15.4 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding RRM_1 PF00076.22 KZN86723.1 - 3.6e-24 84.4 0.0 4.2e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KZN86723.1 - 0.005 16.9 0.0 0.0082 16.2 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 KZN86723.1 - 0.031 14.3 0.0 0.036 14.1 0.0 1.1 1 0 0 1 1 1 0 RNA binding motif Gelsolin PF00626.22 KZN86724.1 - 1e-37 127.9 0.7 5.4e-13 48.7 0.1 3.2 3 0 0 3 3 3 3 Gelsolin repeat Romo1 PF10247.9 KZN86725.1 - 0.021 15.2 0.7 0.71 10.3 0.0 2.3 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Sulfotransfer_4 PF17784.1 KZN86726.1 - 1.5e-52 178.6 0.0 1.7e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KZN86726.1 - 3.5e-05 24.3 0.2 0.00065 20.2 0.2 2.0 1 1 0 1 1 1 1 Sulfotransferase family Lipase_GDSL_2 PF13472.6 KZN86727.1 - 3.2e-15 57.0 0.1 4.9e-15 56.4 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KZN86727.1 - 2.1e-09 37.7 0.0 3.2e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KZN86727.1 - 0.023 14.8 0.2 0.063 13.4 0.0 1.8 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family ATP-grasp_2 PF08442.10 KZN86728.1 - 4.4e-41 140.7 0.0 6.4e-41 140.2 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 KZN86728.1 - 1.3e-18 67.3 0.3 4.5e-18 65.5 0.4 1.8 2 0 0 2 2 2 1 CoA-ligase Methyltransf_23 PF13489.6 KZN86729.1 - 1.9e-13 50.6 0.0 3.1e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN86729.1 - 3.6e-09 37.2 0.0 1.1e-08 35.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN86729.1 - 6e-05 23.6 0.0 0.00021 21.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN86729.1 - 0.0004 20.2 0.0 0.0019 18.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN86729.1 - 0.00065 20.4 0.0 0.01 16.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KZN86729.1 - 0.0066 15.9 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 KZN86729.1 - 0.036 13.5 0.1 2.2 7.6 0.0 2.1 1 1 1 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KZN86729.1 - 0.06 12.7 0.0 0.85 8.9 0.0 2.1 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 KZN86729.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CheR PF01739.18 KZN86729.1 - 0.12 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain HlyIII PF03006.20 KZN86730.1 - 7.6e-36 123.9 13.9 8.9e-36 123.7 13.9 1.0 1 0 0 1 1 1 1 Haemolysin-III related SnAC PF14619.6 KZN86730.1 - 0.18 12.4 0.0 0.28 11.8 0.0 1.2 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex PAS_9 PF13426.7 KZN86731.1 - 1.4e-16 60.6 0.0 1e-14 54.6 0.0 2.9 3 0 0 3 3 3 1 PAS domain PAS_4 PF08448.10 KZN86731.1 - 0.00075 19.7 0.0 2.2 8.6 0.0 2.9 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 KZN86731.1 - 0.0013 18.8 0.0 0.013 15.5 0.0 2.3 2 0 0 2 2 2 1 PAS fold AA_permease_2 PF13520.6 KZN86732.1 - 1.5e-56 192.1 53.8 1.8e-56 191.8 53.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN86732.1 - 7.6e-22 77.5 42.0 1e-21 77.1 42.0 1.0 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_4 PF13420.7 KZN86733.1 - 1.5e-05 25.1 0.0 0.0065 16.6 0.0 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KZN86733.1 - 0.055 13.7 0.0 0.076 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF2156 PF09924.9 KZN86735.1 - 7e-32 110.6 0.0 1.1e-31 110.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) PX PF00787.24 KZN86736.1 - 9e-19 67.5 0.0 1.4e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 PX domain adh_short PF00106.25 KZN86738.1 - 2.7e-29 102.0 0.8 1.3e-20 73.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KZN86738.1 - 3e-25 89.2 0.3 5.5e-23 81.7 0.3 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN86738.1 - 8.7e-06 25.8 0.0 1.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KZN86738.1 - 0.0025 17.3 0.0 0.0055 16.1 0.0 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) RPN7 PF10602.9 KZN86739.1 - 2.3e-50 170.7 0.1 3.8e-50 170.0 0.1 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KZN86739.1 - 1.6e-11 44.6 0.0 1.3e-10 41.7 0.0 2.3 2 0 0 2 2 2 1 PCI domain TPR_16 PF13432.6 KZN86739.1 - 0.22 12.2 3.6 33 5.2 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_23 PF13489.6 KZN86741.1 - 1.9e-20 73.3 0.0 3.3e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN86741.1 - 2e-10 41.2 0.0 4.8e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN86741.1 - 3e-08 34.3 0.0 4.4e-07 30.6 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN86741.1 - 5.2e-08 33.4 0.0 1.1e-07 32.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN86741.1 - 0.00061 19.6 0.0 0.013 15.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KZN86741.1 - 0.045 13.3 0.0 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_16 PF10294.9 KZN86741.1 - 0.084 12.6 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 KZN86741.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.12 KZN86741.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) p450 PF00067.22 KZN86742.1 - 8.6e-69 232.5 0.0 1e-68 232.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 KZN86743.1 - 9.6e-24 83.7 1.2 1.6e-23 83.0 1.2 1.4 1 0 0 1 1 1 1 FAD binding domain RAP1 PF07218.11 KZN86744.1 - 8.2 4.6 10.0 10 4.3 10.0 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Hamartin PF04388.12 KZN86744.1 - 9.1 4.8 16.5 10 4.6 16.5 1.0 1 0 0 1 1 1 0 Hamartin protein MFS_1 PF07690.16 KZN86745.1 - 3.1e-22 79.0 33.3 1.1e-12 47.5 2.2 3.0 3 0 0 3 3 3 3 Major Facilitator Superfamily ATG22 PF11700.8 KZN86745.1 - 2.4e-06 26.5 1.0 0.00061 18.5 0.3 2.4 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_2 PF13347.6 KZN86745.1 - 5.8e-05 21.8 23.6 0.00029 19.5 4.8 3.5 4 0 0 4 4 4 3 MFS/sugar transport protein MFS_1_like PF12832.7 KZN86745.1 - 0.00043 19.2 5.3 0.095 11.5 0.4 3.3 3 1 0 4 4 4 2 MFS_1 like family DUF1772 PF08592.11 KZN86745.1 - 0.0013 19.0 7.9 0.22 11.9 0.0 4.3 2 1 1 4 4 4 2 Domain of unknown function (DUF1772) Nucleoside_tran PF01733.18 KZN86745.1 - 0.0055 16.1 0.2 0.023 14.1 0.0 2.1 2 0 0 2 2 2 1 Nucleoside transporter DUF485 PF04341.12 KZN86745.1 - 0.019 14.9 0.2 0.019 14.9 0.2 3.2 4 0 0 4 4 4 0 Protein of unknown function, DUF485 Wzy_C PF04932.15 KZN86745.1 - 0.3 10.7 5.8 11 5.6 0.0 3.9 3 1 0 3 3 3 0 O-Antigen ligase zf-RING_2 PF13639.6 KZN86746.1 - 3e-08 33.9 3.2 3e-08 33.9 3.2 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KZN86746.1 - 6.2e-08 32.8 6.7 5.9e-07 29.7 6.7 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KZN86746.1 - 6.1e-07 29.2 0.5 1.6e-06 27.8 0.5 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KZN86746.1 - 2e-05 24.3 3.2 5.9e-05 22.8 3.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KZN86746.1 - 3.9e-05 23.4 5.5 0.00011 21.9 1.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KZN86746.1 - 6.1e-05 22.6 1.0 0.00013 21.5 1.0 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KZN86746.1 - 0.00017 21.5 2.9 0.00049 20.0 0.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KZN86746.1 - 0.00023 21.1 3.2 0.0011 18.9 3.2 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KZN86746.1 - 0.0026 17.8 1.7 0.045 13.8 0.9 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KZN86746.1 - 0.004 17.0 1.8 0.004 17.0 1.8 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KZN86746.1 - 0.034 14.3 1.1 0.071 13.3 1.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING CopD PF05425.13 KZN86746.1 - 0.22 11.9 3.8 0.16 12.4 1.6 1.9 1 1 0 1 1 1 0 Copper resistance protein D zf-RING-like PF08746.11 KZN86746.1 - 0.31 11.4 2.3 0.63 10.4 2.3 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_11 PF17123.5 KZN86746.1 - 0.61 9.9 3.9 0.51 10.1 0.3 2.3 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_4 PF14570.6 KZN86746.1 - 3.6 7.5 4.5 1.4 8.8 1.6 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF3431 PF11913.8 KZN86747.1 - 1.2e-89 299.7 0.0 1.6e-89 299.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Tim17 PF02466.19 KZN86749.1 - 2e-14 53.9 0.9 3.2e-14 53.2 0.5 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Brix PF04427.18 KZN86750.1 - 7.7e-33 114.2 0.0 1.2e-32 113.6 0.0 1.3 1 0 0 1 1 1 1 Brix domain NUP50 PF08911.11 KZN86750.1 - 0.31 11.7 3.2 1.5 9.6 3.2 2.2 1 1 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) Peptidase_M14 PF00246.24 KZN86751.1 - 1.4e-14 54.6 0.1 9.3e-14 51.9 0.0 2.2 2 1 0 2 2 2 1 Zinc carboxypeptidase AstE_AspA PF04952.14 KZN86751.1 - 0.0086 15.2 0.5 0.099 11.7 0.0 2.4 2 1 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family Whirly PF08536.11 KZN86752.1 - 0.2 11.5 0.0 0.82 9.5 0.0 1.9 2 0 0 2 2 2 0 Whirly transcription factor MFS_1 PF07690.16 KZN86753.1 - 2.3e-35 122.2 18.7 3.1e-34 118.5 17.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KZN86753.1 - 0.00016 21.1 2.9 0.00016 21.1 2.9 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB ABC_membrane PF00664.23 KZN86755.1 - 7.2e-75 252.2 38.7 5.5e-39 134.5 16.0 3.1 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KZN86755.1 - 6.1e-66 221.1 0.0 5.4e-33 114.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KZN86755.1 - 1.2e-12 47.8 4.4 4.1e-05 23.1 0.4 4.6 4 1 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KZN86755.1 - 4.3e-09 36.8 0.2 0.012 15.9 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KZN86755.1 - 5.9e-09 36.5 0.2 0.00016 22.1 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KZN86755.1 - 6.4e-09 35.4 0.3 0.00046 19.9 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KZN86755.1 - 2.7e-08 33.9 0.0 0.0099 15.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KZN86755.1 - 6.8e-06 26.7 0.0 0.042 14.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 KZN86755.1 - 2.2e-05 23.5 0.1 0.038 12.8 0.1 3.2 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 KZN86755.1 - 2.2e-05 24.3 0.0 0.24 11.1 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KZN86755.1 - 5.2e-05 23.7 0.6 4.8 7.6 0.0 4.3 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KZN86755.1 - 9.4e-05 22.2 0.2 0.57 9.9 0.0 3.5 4 0 0 4 4 4 2 AAA domain AAA_21 PF13304.6 KZN86755.1 - 0.00014 21.8 0.1 1 9.1 0.0 3.1 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 KZN86755.1 - 0.00016 21.7 0.1 0.43 10.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KZN86755.1 - 0.00026 20.6 0.1 0.74 9.3 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_7 PF12775.7 KZN86755.1 - 0.00027 20.5 0.0 0.8 9.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 KZN86755.1 - 0.00028 21.1 0.1 0.6 10.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KZN86755.1 - 0.0012 18.6 0.0 0.78 9.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KZN86755.1 - 0.0015 17.8 0.0 1 8.5 0.0 2.9 3 0 0 3 3 3 1 NB-ARC domain Rad17 PF03215.15 KZN86755.1 - 0.0015 18.5 0.0 0.42 10.5 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain RNA_helicase PF00910.22 KZN86755.1 - 0.0041 17.5 0.0 1.6 9.2 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.6 KZN86755.1 - 0.0041 17.4 0.1 0.51 10.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KZN86755.1 - 0.0061 17.1 0.0 2.2 8.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 KZN86755.1 - 0.0065 15.7 0.0 0.62 9.2 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit Zeta_toxin PF06414.12 KZN86755.1 - 0.0069 15.7 0.0 3.5 6.9 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin IstB_IS21 PF01695.17 KZN86755.1 - 0.0094 15.7 0.1 11 5.7 0.0 3.5 4 0 0 4 4 4 0 IstB-like ATP binding protein MMR_HSR1 PF01926.23 KZN86755.1 - 0.012 15.7 0.1 3.5 7.7 0.0 3.0 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_17 PF13207.6 KZN86755.1 - 0.03 14.8 0.0 7.7 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KZN86755.1 - 0.031 14.2 0.0 12 5.8 0.0 2.7 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.17 KZN86755.1 - 0.032 14.0 0.2 4.9 6.8 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SbcCD_C PF13558.6 KZN86755.1 - 0.043 14.1 0.9 17 5.7 0.2 3.7 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_PrkA PF08298.11 KZN86755.1 - 0.055 12.4 0.0 3.2 6.6 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain SRP54 PF00448.22 KZN86755.1 - 0.074 12.7 0.0 6.3 6.4 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain APS_kinase PF01583.20 KZN86755.1 - 0.087 12.7 0.1 12 5.7 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase Cytidylate_kin PF02224.18 KZN86755.1 - 0.088 12.5 0.0 5.6 6.6 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase Ploopntkinase3 PF18751.1 KZN86755.1 - 0.094 12.6 0.2 8.2 6.3 0.0 2.8 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 TniB PF05621.11 KZN86755.1 - 0.098 12.1 0.1 4.5 6.6 0.0 3.1 4 0 0 4 4 4 0 Bacterial TniB protein DUF87 PF01935.17 KZN86755.1 - 0.11 12.5 0.0 12 5.9 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Roc PF08477.13 KZN86755.1 - 0.13 12.5 0.0 14 6.0 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MoaE PF02391.17 KZN86755.1 - 0.18 12.1 0.2 18 5.6 0.0 2.7 2 0 0 2 2 2 0 MoaE protein PRK PF00485.18 KZN86755.1 - 0.18 11.5 0.1 20 4.8 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family adh_short_C2 PF13561.6 KZN86756.1 - 1.8e-51 175.0 0.1 2.2e-51 174.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN86756.1 - 1.8e-45 154.8 0.6 2.5e-45 154.4 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN86756.1 - 2.1e-05 24.5 0.1 3.1e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 KR domain F_bP_aldolase PF01116.20 KZN86757.1 - 2.7e-79 266.5 0.1 3.1e-79 266.4 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II PTE PF02126.18 KZN86757.1 - 0.0042 16.6 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotriesterase family Amidohydro_1 PF01979.20 KZN86757.1 - 0.0099 15.2 0.4 2.8 7.2 0.3 2.4 1 1 0 2 2 2 2 Amidohydrolase family CobS PF02654.15 KZN86757.1 - 0.021 15.0 0.6 0.03 14.5 0.0 1.5 2 0 0 2 2 2 0 Cobalamin-5-phosphate synthase Fungal_trans_2 PF11951.8 KZN86758.1 - 1.9e-19 69.8 4.3 1.6e-16 60.1 2.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN86758.1 - 2.1e-08 34.2 9.6 3.7e-08 33.4 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN86758.1 - 0.00019 20.6 5.3 0.00032 19.8 4.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain APH PF01636.23 KZN86760.1 - 9.8e-09 35.5 0.0 5.4e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN86760.1 - 5.7e-05 22.8 0.0 9.1e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase NAD_binding_4 PF07993.12 KZN86761.1 - 1.7e-42 145.4 0.0 5e-42 143.8 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.28 KZN86761.1 - 1e-20 73.8 0.0 3.6e-16 58.8 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.21 KZN86761.1 - 1.4e-12 47.7 0.0 3.1e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KZN86761.1 - 9.5e-08 32.3 0.0 1.1e-06 28.9 0.0 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KZN86761.1 - 0.00019 20.5 0.0 0.0005 19.2 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KZN86761.1 - 0.013 14.6 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.10 KZN86761.1 - 0.019 14.8 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 KR domain p450 PF00067.22 KZN86762.1 - 9.1e-63 212.6 0.0 1.1e-62 212.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C62 PF12380.8 KZN86762.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Gill-associated viral 3C-like peptidase APH PF01636.23 KZN86763.1 - 3.2e-21 76.4 0.0 4.2e-21 76.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family PIP49_C PF12260.8 KZN86763.1 - 0.016 14.9 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Kdo PF06293.14 KZN86763.1 - 0.031 13.6 0.0 0.045 13.1 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fructosamin_kin PF03881.14 KZN86763.1 - 0.082 12.1 0.0 0.094 11.9 0.0 1.1 1 0 0 1 1 1 0 Fructosamine kinase Abhydrolase_6 PF12697.7 KZN86764.1 - 6e-11 43.4 1.6 1.7e-10 41.9 1.6 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KZN86764.1 - 0.027 13.7 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MFS_1 PF07690.16 KZN86765.1 - 6.7e-31 107.5 30.7 1.8e-21 76.5 18.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN86765.1 - 4.7e-17 62.0 20.6 5.8e-17 61.7 18.5 2.3 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KZN86765.1 - 0.00013 20.9 7.3 0.00034 19.6 5.3 2.1 2 0 0 2 2 2 1 MFS_1 like family Abhydrolase_3 PF07859.13 KZN86766.1 - 3.9e-41 141.2 0.0 4.9e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KZN86766.1 - 8.4e-06 24.9 0.0 2.2e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 KZN86766.1 - 0.00017 21.3 0.0 0.00076 19.1 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KZN86766.1 - 0.00043 19.8 0.0 0.0027 17.2 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 KZN86766.1 - 0.00046 20.2 0.0 0.00098 19.1 0.0 1.5 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 KZN86766.1 - 0.00056 19.6 0.0 0.029 14.0 0.0 2.3 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 KZN86766.1 - 0.0019 17.9 0.0 0.047 13.3 0.0 2.1 2 0 0 2 2 2 1 Putative esterase Abhydrolase_6 PF12697.7 KZN86766.1 - 0.0073 16.9 2.0 0.013 16.2 1.9 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 KZN86766.1 - 0.012 14.7 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_2 PF02230.16 KZN86766.1 - 0.015 15.2 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase AXE1 PF05448.12 KZN86766.1 - 0.015 14.0 0.0 0.098 11.3 0.0 1.9 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.7 KZN86766.1 - 0.015 14.2 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Say1_Mug180 PF10340.9 KZN86766.1 - 0.085 11.7 0.0 1.5 7.6 0.0 2.0 1 1 1 2 2 2 0 Steryl acetyl hydrolase Esterase_phd PF10503.9 KZN86766.1 - 0.14 11.6 0.0 0.33 10.4 0.0 1.5 2 0 0 2 2 2 0 Esterase PHB depolymerase MFS_1 PF07690.16 KZN86767.1 - 6.2e-30 104.3 19.3 6.2e-30 104.3 19.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN86767.1 - 3e-06 26.4 9.5 3e-06 26.4 9.5 3.0 2 1 0 3 3 3 2 Sugar (and other) transporter LamB_YcsF PF03746.16 KZN86768.1 - 7.6e-82 274.6 0.0 9.4e-82 274.3 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family CT_A_B PF02626.15 KZN86770.1 - 2.8e-73 246.8 0.0 4.2e-73 246.2 0.0 1.3 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 KZN86770.1 - 4.5e-55 186.4 0.0 7.7e-55 185.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KZN86770.1 - 3e-40 137.2 0.2 5.9e-40 136.2 0.2 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain CT_C_D PF02682.16 KZN86770.1 - 1.1e-33 116.7 0.0 2.4e-33 115.6 0.0 1.6 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_C PF02785.19 KZN86770.1 - 1.3e-32 112.1 0.0 2.4e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KZN86770.1 - 1.2e-08 34.6 1.6 2.5e-07 30.4 1.7 2.7 1 1 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KZN86770.1 - 1.5e-05 24.7 0.0 3.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 KZN86770.1 - 0.00019 21.2 0.4 0.066 13.1 0.1 2.8 3 0 0 3 3 3 2 Biotin-lipoyl like ATP-grasp_5 PF13549.6 KZN86770.1 - 0.054 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Glyco_hydro_31 PF01055.26 KZN86771.1 - 4.1e-149 497.5 2.7 5.3e-149 497.2 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KZN86771.1 - 7.1e-31 106.8 0.0 1.2e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KZN86771.1 - 0.022 15.1 0.3 0.081 13.3 0.3 2.0 1 0 0 1 1 1 0 Galactose mutarotase-like Rotavirus_VP7 PF05868.11 KZN86771.1 - 0.17 11.3 0.2 0.51 9.7 0.0 1.8 2 1 0 2 2 2 0 Rotavirus major outer capsid protein VP7 Aldose_epim PF01263.20 KZN86772.1 - 2.7e-48 164.8 0.4 3.9e-48 164.3 0.4 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase Arm-DNA-bind_2 PF12167.8 KZN86772.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Arm DNA-binding domain GMC_oxred_N PF00732.19 KZN86773.1 - 1.6e-75 254.3 0.0 2.1e-75 253.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KZN86773.1 - 2.8e-23 83.0 0.0 4.9e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 KZN86773.1 - 0.00031 20.0 0.0 0.0006 19.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KZN86773.1 - 0.00034 20.3 0.1 0.0014 18.3 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KZN86773.1 - 0.00034 20.8 0.1 0.00082 19.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KZN86773.1 - 0.00053 19.2 0.0 0.0011 18.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KZN86773.1 - 0.045 12.8 0.0 0.071 12.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KZN86773.1 - 0.073 12.3 0.1 0.28 10.4 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lactonase PF10282.9 KZN86774.1 - 3.8e-73 246.7 0.0 4.8e-73 246.4 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller NHL PF01436.21 KZN86774.1 - 0.014 15.4 0.5 0.67 10.1 0.2 2.6 2 0 0 2 2 2 0 NHL repeat Fungal_trans_2 PF11951.8 KZN86776.1 - 2.2e-12 46.5 0.1 3.1e-12 46.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN86776.1 - 1.5e-05 25.0 6.3 3.2e-05 23.9 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_MalT PF17874.1 KZN86776.1 - 0.00072 19.0 0.4 0.0014 18.0 0.4 1.5 1 0 0 1 1 1 1 MalT-like TPR region Pkinase PF00069.25 KZN86777.1 - 1.1e-16 61.1 0.0 2.1e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 KZN86777.1 - 4.4e-16 59.2 0.1 2.6e-05 24.7 0.2 3.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.17 KZN86777.1 - 9.3e-12 44.8 0.0 2.9e-11 43.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Ank_3 PF13606.6 KZN86777.1 - 3.1e-09 36.3 0.3 0.033 14.7 0.0 6.1 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.6 KZN86777.1 - 2.7e-08 34.2 0.1 0.00027 21.4 0.1 4.4 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 KZN86777.1 - 5.1e-07 29.8 0.5 0.0056 17.1 0.0 4.7 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 KZN86777.1 - 2.7e-05 24.4 0.9 1.3 9.5 0.0 5.1 2 1 4 6 6 6 2 Ankyrin repeats (many copies) Sugar_tr PF00083.24 KZN86778.1 - 3.2e-51 174.6 13.3 3.3e-50 171.3 13.3 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN86778.1 - 7.8e-06 25.1 19.4 7.8e-06 25.1 19.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily CorA PF01544.18 KZN86780.1 - 1.3e-09 37.8 1.0 1.9e-09 37.3 1.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein UPF0093 PF03653.13 KZN86780.1 - 0.0018 18.5 0.1 0.0022 18.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0093) Virul_fac_BrkB PF03631.15 KZN86780.1 - 0.011 15.4 0.2 0.012 15.3 0.2 1.1 1 0 0 1 1 1 0 Virulence factor BrkB EMP70 PF02990.16 KZN86780.1 - 0.014 14.1 0.0 0.017 13.8 0.0 1.0 1 0 0 1 1 1 0 Endomembrane protein 70 Cytochrom_B_N_2 PF13631.6 KZN86780.1 - 0.023 14.7 0.0 0.028 14.4 0.0 1.1 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Insulin_TMD PF17870.1 KZN86780.1 - 0.22 11.6 0.6 0.22 11.6 0.6 1.6 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment tRNA-synt_1 PF00133.22 KZN86781.1 - 5.1e-224 745.0 0.0 5.8e-223 741.5 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KZN86781.1 - 3.6e-31 108.2 1.4 1.2e-30 106.5 1.4 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KZN86781.1 - 1.4e-14 53.7 0.0 3.8e-07 29.2 0.0 4.4 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KZN86781.1 - 5.3e-07 29.3 4.3 9.9e-05 21.9 0.0 2.7 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 KZN86781.1 - 0.0016 18.7 7.1 0.0016 18.7 7.1 2.7 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 KZN86781.1 - 0.063 12.6 0.0 0.6 9.4 0.0 2.4 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain PepSY PF03413.19 KZN86781.1 - 0.16 12.6 4.6 0.37 11.4 0.0 2.8 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Pkinase PF00069.25 KZN86782.1 - 4.4e-64 216.4 0.0 5.1e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN86782.1 - 7e-18 64.8 0.0 9.7e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KZN86782.1 - 3.4e-07 30.4 0.5 0.00011 22.2 0.1 2.7 2 1 0 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KZN86782.1 - 0.0031 16.3 0.0 0.0057 15.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KZN86782.1 - 0.0082 15.5 0.1 0.014 14.8 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KZN86782.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 KZN86782.1 - 0.025 14.1 0.6 0.047 13.3 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Aconitase_B_N PF11791.8 KZN86782.1 - 0.071 13.2 0.0 0.53 10.3 0.0 2.1 2 1 0 2 2 2 0 Aconitate B N-terminal domain RNase_P_p30 PF01876.16 KZN86783.1 - 1e-66 224.5 0.0 1.3e-66 224.1 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 Ureidogly_lyase PF04115.12 KZN86784.1 - 2e-64 216.8 0.0 2.3e-64 216.6 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase MutS_V PF00488.21 KZN86785.1 - 2.4e-72 242.9 0.1 4.5e-72 242.0 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KZN86785.1 - 9e-44 150.0 5.2 2.5e-43 148.5 5.2 1.8 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KZN86785.1 - 2.3e-20 72.9 0.0 6.1e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KZN86785.1 - 9.5e-07 29.2 0.0 2.9e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 MutS domain II CCDC92 PF14916.6 KZN86785.1 - 0.015 15.0 0.0 0.043 13.6 0.0 1.7 1 0 0 1 1 1 0 Coiled-coil domain of unknown function AAA_29 PF13555.6 KZN86785.1 - 0.052 13.3 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KZN86785.1 - 0.089 13.3 0.5 0.31 11.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain Sec63 PF02889.16 KZN86786.1 - 1.8e-166 551.7 0.1 6.4e-93 310.6 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KZN86786.1 - 6.6e-51 172.6 0.0 5.1e-28 98.0 0.0 3.6 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 KZN86786.1 - 3.3e-29 101.3 0.0 1.2e-28 99.5 0.0 2.0 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 KZN86786.1 - 5.7e-24 85.0 0.0 1.2e-11 44.9 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KZN86786.1 - 7.6e-12 45.6 0.0 5.3e-07 30.0 0.0 3.7 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KZN86786.1 - 1.9e-06 28.2 0.2 0.04 14.2 0.1 3.4 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 KZN86786.1 - 0.00054 19.1 0.0 1 8.4 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein PhoH PF02562.16 KZN86786.1 - 0.0019 17.7 0.0 0.13 11.7 0.0 2.7 2 0 0 2 2 2 1 PhoH-like protein UvrD-helicase PF00580.21 KZN86786.1 - 0.074 12.6 0.0 1.4 8.3 0.0 2.7 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 KZN86786.1 - 0.15 12.4 0.1 11 6.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain Peptidase_S9 PF00326.21 KZN86787.1 - 3e-49 167.4 0.1 5.9e-49 166.4 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KZN86787.1 - 0.00048 19.9 0.2 0.00094 18.9 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 KZN86787.1 - 0.0062 15.3 0.1 0.1 11.3 0.1 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) PD40 PF07676.12 KZN86787.1 - 0.19 11.7 2.0 6.7 6.8 0.0 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Esterase PF00756.20 KZN86787.1 - 0.24 11.0 2.0 0.4 10.3 0.4 2.1 2 1 0 2 2 2 0 Putative esterase Glyco_hydro_43 PF04616.14 KZN86788.1 - 3.3e-27 95.6 1.8 1.6e-16 60.4 0.6 2.3 2 1 0 2 2 2 2 Glycosyl hydrolases family 43 MFS_1 PF07690.16 KZN86789.1 - 7.6e-24 84.3 36.0 1.4e-21 76.8 29.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.25 KZN86790.1 - 5.9e-10 38.9 0.0 3e-07 30.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KZN86790.1 - 5.7e-05 22.8 0.0 0.00035 20.2 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN86790.1 - 0.0058 16.6 0.0 0.0097 15.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Pkinase PF00069.25 KZN86791.1 - 2.4e-36 125.4 0.0 1.3e-20 73.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KZN86791.1 - 8e-13 48.3 0.0 9.3e-06 25.1 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KZN86791.1 - 0.0015 17.9 0.0 0.41 9.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KZN86791.1 - 0.05 13.5 0.0 0.11 12.3 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family CAP_GLY PF01302.25 KZN86792.1 - 2.9e-15 56.0 0.5 5.3e-15 55.2 0.5 1.4 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 KZN86792.1 - 4.8e-11 42.2 10.6 4.6e-05 23.2 0.9 2.7 2 0 0 2 2 2 2 CLIP1 zinc knuckle TPR_MLP1_2 PF07926.12 KZN86792.1 - 0.0017 18.4 8.5 0.0017 18.4 8.5 3.3 3 0 0 3 3 3 1 TPR/MLP1/MLP2-like protein FAM76 PF16046.5 KZN86792.1 - 0.0069 15.8 3.2 0.0069 15.8 3.2 2.8 1 1 0 2 2 2 1 FAM76 protein SlyX PF04102.12 KZN86792.1 - 0.01 16.5 24.4 0.93 10.2 7.0 4.1 3 0 0 3 3 3 0 SlyX APG6_N PF17675.1 KZN86792.1 - 0.014 15.9 31.6 0.18 12.3 1.8 3.4 3 0 0 3 3 3 0 Apg6 coiled-coil region EzrA PF06160.12 KZN86792.1 - 0.057 11.6 22.4 0.25 9.5 9.3 3.1 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA AAA_13 PF13166.6 KZN86792.1 - 0.083 11.5 21.6 0.0094 14.7 10.7 2.5 1 1 0 2 2 2 0 AAA domain DUF1664 PF07889.12 KZN86792.1 - 0.087 12.9 15.4 0.24 11.5 3.1 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 KZN86792.1 - 0.099 12.7 28.5 4.6 7.3 4.1 5.0 5 0 0 5 5 5 0 TATA element modulatory factor 1 DNA binding Fez1 PF06818.15 KZN86792.1 - 0.1 13.0 37.2 0.25 11.8 14.0 3.4 1 1 1 3 3 3 0 Fez1 BLOC1_2 PF10046.9 KZN86792.1 - 0.22 11.9 18.2 1.2 9.4 4.9 3.8 3 1 0 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FliJ PF02050.16 KZN86792.1 - 0.22 11.7 25.2 1.4 9.2 0.4 4.1 2 1 1 4 4 4 0 Flagellar FliJ protein Golgin_A5 PF09787.9 KZN86792.1 - 0.25 10.8 33.3 0.26 10.7 1.0 3.2 2 1 1 3 3 3 0 Golgin subfamily A member 5 NPV_P10 PF05531.12 KZN86792.1 - 0.41 11.1 10.9 5.8 7.4 1.4 3.7 4 0 0 4 4 3 0 Nucleopolyhedrovirus P10 protein Tropomyosin PF00261.20 KZN86792.1 - 0.43 9.9 33.8 1.1 8.6 0.8 3.0 2 1 1 3 3 3 0 Tropomyosin Spc7 PF08317.11 KZN86792.1 - 0.44 9.4 34.2 0.33 9.8 5.1 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein YPEB PF14620.6 KZN86792.1 - 0.57 9.5 11.1 3.6 6.8 5.0 2.6 2 1 0 2 2 2 0 YpeB sporulation Pox_A_type_inc PF04508.12 KZN86792.1 - 1 9.4 13.3 3.9 7.5 2.5 4.1 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat C1_2 PF03107.16 KZN86792.1 - 2.1 8.7 4.2 20 5.6 0.3 2.3 2 0 0 2 2 2 0 C1 domain DUF812 PF05667.11 KZN86792.1 - 2.2 7.1 28.1 0.066 12.1 13.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF3552 PF12072.8 KZN86792.1 - 2.5 7.5 38.7 0.61 9.5 3.5 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF3552) BST2 PF16716.5 KZN86792.1 - 2.8 8.6 22.3 10 6.8 1.9 3.8 3 1 1 4 4 4 0 Bone marrow stromal antigen 2 zf_PR_Knuckle PF18445.1 KZN86792.1 - 4.6 7.1 4.8 10 6.0 0.5 2.5 2 0 0 2 2 2 0 PR zinc knuckle motif FliD_N PF02465.18 KZN86792.1 - 4.6 8.0 7.0 13 6.6 0.3 3.3 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Prominin PF05478.11 KZN86792.1 - 5.7 4.8 5.6 8.7 4.2 5.6 1.4 1 0 0 1 1 1 0 Prominin 3-HAO PF06052.12 KZN86793.1 - 1.1e-55 187.4 0.0 1.3e-55 187.2 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KZN86793.1 - 0.00042 20.0 0.0 0.00086 19.0 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KZN86793.1 - 0.0025 17.4 0.1 0.0037 16.9 0.1 1.2 1 0 0 1 1 1 1 Cupin DZR PF12773.7 KZN86793.1 - 0.0082 16.1 1.1 0.018 15.1 1.1 1.6 1 0 0 1 1 1 1 Double zinc ribbon AraC_binding PF02311.19 KZN86793.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain RTC_insert PF05189.13 KZN86794.1 - 2.6e-27 95.3 0.0 4.3e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 KZN86794.1 - 2.6e-26 92.2 0.1 3.1e-26 91.9 0.1 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase SLAC1 PF03595.17 KZN86795.1 - 1.3e-82 277.7 38.0 1.5e-82 277.5 38.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel HSCB_C PF07743.13 KZN86797.1 - 1.8e-20 73.2 0.7 8e-20 71.1 0.1 2.0 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 KZN86797.1 - 8.5e-06 25.8 0.0 1.8e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.32 KZN86798.1 - 4.8e-30 103.2 21.7 1.1e-06 29.2 3.0 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat PRP4 PF08799.11 KZN86798.1 - 1.6e-14 53.1 5.4 1.6e-14 53.1 5.4 2.0 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 KZN86798.1 - 6.7e-09 35.9 0.1 1.6 9.1 0.0 5.0 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KZN86798.1 - 0.023 14.0 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 WD40-like domain eIF2A PF08662.11 KZN86798.1 - 0.11 12.4 0.0 8.3 6.2 0.0 2.8 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A SpoIIE PF07228.12 KZN86799.1 - 4.2e-10 39.8 0.1 1.9e-09 37.7 0.1 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KZN86799.1 - 1.1e-06 28.4 0.1 2.3e-06 27.4 0.1 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KZN86799.1 - 1.7e-05 24.6 0.1 0.18 11.4 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PWWP PF00855.17 KZN86800.1 - 3.8e-17 62.5 0.0 3.8e-17 62.5 0.0 3.1 3 1 0 3 3 3 1 PWWP domain PAP2_3 PF14378.6 KZN86801.1 - 4.2e-29 101.6 16.2 2.6e-13 50.1 0.1 3.4 3 0 0 3 3 3 3 PAP2 superfamily PAP2 PF01569.21 KZN86801.1 - 0.00045 20.0 3.1 0.00095 18.9 0.5 2.4 2 1 0 2 2 2 1 PAP2 superfamily MFS_1 PF07690.16 KZN86801.1 - 0.012 14.5 4.1 0.055 12.4 4.4 1.9 1 1 1 2 2 2 0 Major Facilitator Superfamily PrgI PF12666.7 KZN86801.1 - 0.44 11.3 3.4 0.62 10.8 0.8 2.3 2 0 0 2 2 2 0 PrgI family protein PAP2_C PF14360.6 KZN86801.1 - 2.4 8.8 7.7 0.21 12.1 0.4 2.8 3 0 0 3 3 3 0 PAP2 superfamily C-terminal ComA PF02679.15 KZN86802.1 - 2.4e-88 295.7 0.0 2.8e-88 295.5 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) Fungal_trans PF04082.18 KZN86803.1 - 5.9e-12 45.2 0.0 9.7e-12 44.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Optomotor-blind PF11078.8 KZN86803.1 - 1.1 9.9 4.9 0.68 10.5 1.8 2.3 2 0 0 2 2 2 0 Optomotor-blind protein N-terminal region SH3_1 PF00018.28 KZN86805.1 - 1.1e-33 114.5 5.9 4.8e-13 48.5 0.1 4.1 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.12 KZN86805.1 - 3.9e-32 109.9 0.2 6.7e-32 109.1 0.2 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.6 KZN86805.1 - 1.6e-31 107.9 8.0 1e-12 47.7 0.5 4.0 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 KZN86805.1 - 1e-18 66.7 0.2 2.9e-07 30.1 0.0 4.1 4 0 0 4 4 4 3 Variant SH3 domain SAM_4 PF18017.1 KZN86805.1 - 3.3e-05 23.8 0.0 7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_10 PF17902.1 KZN86805.1 - 5.5e-05 23.2 0.1 0.77 9.9 0.0 3.5 3 0 0 3 3 3 2 SH3 domain SH3_3 PF08239.11 KZN86805.1 - 0.005 17.1 5.7 0.14 12.5 0.7 3.2 3 0 0 3 3 3 1 Bacterial SH3 domain DUF1720 PF08226.11 KZN86805.1 - 0.076 13.4 174.0 1.8 9.0 13.6 7.0 1 1 3 4 4 4 0 Domain of unknown function (DUF1720) PRKCSH PF07915.13 KZN86806.1 - 6.5e-19 68.7 0.3 6.5e-19 68.7 0.3 2.9 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 KZN86806.1 - 0.0003 20.5 0.5 0.0029 17.3 0.5 2.1 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein Pirin PF02678.16 KZN86807.1 - 1.1e-30 105.7 0.1 2e-30 104.9 0.1 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 KZN86807.1 - 1.2e-24 86.6 0.0 6.2e-24 84.4 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 KZN86807.1 - 8.7e-07 28.6 0.5 0.00014 21.5 0.9 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KZN86807.1 - 0.018 14.7 0.1 0.34 10.6 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF861) LRR_4 PF12799.7 KZN86808.1 - 1.3e-05 25.5 4.5 16 6.1 0.0 6.0 3 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KZN86808.1 - 0.0042 17.0 14.2 0.0057 16.6 0.0 6.4 9 0 0 9 9 9 1 Leucine Rich repeat Pinin_SDK_N PF04697.13 KZN86808.1 - 2.4 8.8 7.0 2.1 9.0 4.0 2.0 2 0 0 2 2 2 0 pinin/SDK conserved region SNF2_N PF00176.23 KZN86809.1 - 1.2e-50 172.2 0.5 9.2e-50 169.3 0.4 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KZN86809.1 - 1.7e-16 60.5 0.0 6e-16 58.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KZN86809.1 - 1.5e-06 28.3 0.0 5.2e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KZN86809.1 - 1.8e-05 24.5 12.1 1.8e-05 24.5 12.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 KZN86809.1 - 0.0026 17.6 0.0 0.0056 16.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_3 PF13920.6 KZN86809.1 - 0.0052 16.6 11.0 0.0052 16.6 11.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.6 KZN86809.1 - 0.0061 15.5 0.0 0.015 14.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Zn_Tnp_IS91 PF14319.6 KZN86809.1 - 0.12 12.4 18.0 0.048 13.7 5.5 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain C2 PF00168.30 KZN86810.1 - 9.6e-11 41.9 0.0 1.9e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain ArfGap PF01412.18 KZN86811.1 - 7.2e-34 116.4 0.1 7.2e-34 116.4 0.1 3.0 4 0 0 4 4 4 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 KZN86811.1 - 1.5e-21 77.3 14.6 2.5e-21 76.5 14.6 1.3 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KZN86811.1 - 3.5e-12 46.8 0.3 1.2e-11 45.1 0.3 2.0 1 0 0 1 1 1 1 PH domain PMEI PF04043.15 KZN86811.1 - 0.033 14.5 0.4 0.1 12.9 0.4 1.8 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor YTH PF04146.15 KZN86812.1 - 3.2e-61 206.1 0.0 5e-61 205.5 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 KZN86812.1 - 5.6e-08 32.5 0.0 1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KZN86812.1 - 0.014 15.2 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Sugar_tr PF00083.24 KZN86814.1 - 4.9e-139 464.1 25.8 5.9e-139 463.8 25.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN86814.1 - 8.9e-26 90.6 48.8 9.7e-21 74.1 25.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KZN86814.1 - 3.8e-09 35.6 18.8 4.3e-05 22.3 1.5 2.7 2 1 1 3 3 3 2 MFS/sugar transport protein PI3_PI4_kinase PF00454.27 KZN86815.1 - 2.8e-39 135.4 0.0 4.2e-28 98.8 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KZN86815.1 - 3.6e-24 85.2 0.0 7.8e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 KZN86815.1 - 0.06 12.7 0.1 0.2 11.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) Pkinase PF00069.25 KZN86816.1 - 6.1e-76 255.3 0.0 7.9e-76 254.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN86816.1 - 2.4e-36 125.4 0.0 3.4e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KZN86816.1 - 8.5e-14 51.7 0.0 1.8e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KZN86816.1 - 9.9e-11 41.5 0.0 1.4e-08 34.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KZN86816.1 - 5e-07 28.8 0.1 3.5e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 KZN86816.1 - 8.3e-05 22.8 0.0 0.00018 21.7 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain APH PF01636.23 KZN86816.1 - 0.00044 20.2 0.2 0.0014 18.6 0.2 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KZN86816.1 - 0.003 17.2 0.0 0.59 9.7 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KZN86816.1 - 0.03 13.7 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KZN86816.1 - 0.13 11.8 0.1 0.69 9.4 0.0 2.0 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL p450 PF00067.22 KZN86817.1 - 1.4e-75 254.9 0.0 1.8e-75 254.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 IGR PF09597.10 KZN86818.1 - 3.7e-23 81.4 0.4 6.3e-23 80.6 0.4 1.4 1 0 0 1 1 1 1 IGR protein motif Pkinase PF00069.25 KZN86819.1 - 2e-62 210.9 0.0 2.4e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN86819.1 - 2.1e-32 112.5 0.0 2.8e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KZN86819.1 - 0.015 14.7 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KZN86819.1 - 0.043 13.7 0.0 0.24 11.3 0.0 1.9 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kinesin PF00225.23 KZN86820.1 - 2.1e-96 322.8 0.0 4.1e-96 321.8 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KZN86820.1 - 1e-23 83.9 0.0 2.6e-23 82.6 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Lebercilin PF15619.6 KZN86820.1 - 0.0043 16.7 0.1 0.0043 16.7 0.1 2.5 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease PKcGMP_CC PF16808.5 KZN86820.1 - 0.013 15.4 2.9 0.12 12.3 0.4 3.2 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Med9 PF07544.13 KZN86820.1 - 0.3 11.2 0.0 0.3 11.2 0.0 2.4 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 FAM76 PF16046.5 KZN86820.1 - 6.5 6.0 8.2 8.8 5.6 0.0 3.1 1 1 2 3 3 3 0 FAM76 protein DAGAT PF03982.13 KZN86821.1 - 3e-90 302.2 0.0 3.6e-90 301.9 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DUF4020 PF13212.6 KZN86821.1 - 0.063 13.1 0.1 0.093 12.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4020) Rer1 PF03248.13 KZN86821.1 - 2.1 8.1 6.0 1.4 8.7 4.0 1.7 1 1 1 2 2 2 0 Rer1 family G-patch PF01585.23 KZN86822.1 - 4.1e-06 26.6 0.2 6.4e-05 22.8 0.2 2.5 1 1 0 1 1 1 1 G-patch domain Macoilin PF09726.9 KZN86822.1 - 0.29 9.7 23.2 0.34 9.4 23.2 1.1 1 0 0 1 1 1 0 Macoilin family TFIIF_alpha PF05793.12 KZN86822.1 - 0.55 8.7 40.4 0.71 8.4 40.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SRP-alpha_N PF04086.13 KZN86822.1 - 0.78 9.6 29.6 1.1 9.1 29.6 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Raftlin PF15250.6 KZN86822.1 - 1.9 7.1 15.7 2.6 6.7 15.7 1.2 1 0 0 1 1 1 0 Raftlin Asp-B-Hydro_N PF05279.11 KZN86822.1 - 3.5 7.6 19.7 4.9 7.2 19.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region GREB1 PF15782.5 KZN86822.1 - 3.8 4.5 19.4 4.8 4.2 19.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF3807 PF12720.7 KZN86822.1 - 6 7.1 29.7 14 5.9 29.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) CDC45 PF02724.14 KZN86822.1 - 6.4 4.9 29.8 8.8 4.5 29.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KZN86822.1 - 6.5 5.4 24.8 9.1 4.9 24.8 1.2 1 0 0 1 1 1 0 Presenilin Smg8_Smg9 PF10220.9 KZN86822.1 - 9 4.5 18.5 11 4.1 18.5 1.1 1 0 0 1 1 1 0 Smg8_Smg9 Syja_N PF02383.18 KZN86823.1 - 5.1e-72 242.9 0.0 6.8e-72 242.5 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 KZN86823.1 - 1.4e-10 41.1 0.2 2.6e-10 40.2 0.2 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RAMP4 PF06624.12 KZN86824.1 - 2.3e-23 82.0 0.0 2.6e-23 81.8 0.0 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Adaptin_N PF01602.20 KZN86825.1 - 8.7e-86 288.5 0.0 2.4e-80 270.6 0.2 2.0 2 0 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 KZN86825.1 - 5e-09 36.4 0.0 3.2e-06 27.3 0.0 2.4 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KZN86825.1 - 6.2e-05 22.9 3.5 0.1 12.9 0.1 4.9 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 KZN86825.1 - 0.00017 21.9 3.6 1.3 9.5 0.0 3.6 3 0 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 KZN86825.1 - 0.2 12.2 4.4 35 5.0 0.2 4.2 3 1 1 4 4 4 0 HEAT-like repeat TPR_14 PF13428.6 KZN86826.1 - 7.9e-08 32.5 0.3 0.081 13.8 0.2 4.7 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KZN86826.1 - 1.2e-06 28.1 0.0 0.24 11.1 0.0 3.9 4 0 0 4 4 4 2 TPR repeat TPR_19 PF14559.6 KZN86826.1 - 4.6e-06 27.0 2.9 0.0015 19.0 0.1 3.9 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KZN86826.1 - 7.9e-06 25.9 0.1 0.071 13.5 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KZN86826.1 - 1.1e-05 25.1 0.0 0.00026 20.7 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KZN86826.1 - 1.5e-05 24.7 0.2 0.0038 17.2 0.1 4.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KZN86826.1 - 0.00022 21.2 0.1 0.0015 18.6 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KZN86826.1 - 0.0019 18.3 0.1 0.0077 16.4 0.1 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 KZN86826.1 - 0.053 13.8 5.0 3.7 7.9 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KZN86826.1 - 0.86 9.8 5.6 2.9 8.1 0.1 4.4 7 0 0 7 7 7 0 Tetratricopeptide repeat Hid1 PF12722.7 KZN86827.1 - 2 6.4 4.2 3 5.9 4.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Asp-B-Hydro_N PF05279.11 KZN86827.1 - 2.2 8.3 14.3 3.6 7.6 14.3 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2052 PF09747.9 KZN86827.1 - 5 7.2 13.0 11 6.1 13.0 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Yae1_N PF09811.9 KZN86828.1 - 1.8e-09 37.1 51.6 2.1 8.1 0.2 10.0 4 2 1 5 5 5 1 Essential protein Yae1, N terminal MspA PF09203.11 KZN86828.1 - 0.00017 21.5 5.5 3.7 7.4 5.5 3.2 1 1 0 1 1 1 1 MspA Keratin_2_head PF16208.5 KZN86828.1 - 0.89 9.7 35.6 1.8e+04 -18.4 35.6 4.2 1 1 0 1 1 1 0 Keratin type II head Retrotrans_gag PF03732.17 KZN86829.1 - 1.3e-10 41.4 0.2 1.6e-09 37.9 0.0 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein Gag_p24 PF00607.20 KZN86829.1 - 0.072 12.9 0.0 0.15 11.9 0.0 1.6 2 0 0 2 2 2 0 gag gene protein p24 (core nucleocapsid protein) NOA36 PF06524.12 KZN86830.1 - 0.084 12.2 1.4 0.14 11.4 1.4 1.4 1 0 0 1 1 1 0 NOA36 protein GP67 PF17634.2 KZN86830.1 - 0.18 12.2 0.0 0.18 12.2 0.0 3.0 2 1 1 3 3 3 0 Gene product 67 YccV-like PF08755.11 KZN86831.1 - 6.1e-29 100.4 0.4 1.2e-28 99.4 0.1 1.7 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 KZN86831.1 - 2.1e-11 43.6 0.0 4.3e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 KZN86831.1 - 1e-05 25.3 1.0 2.5e-05 24.1 1.0 1.7 1 0 0 1 1 1 1 F-box-like Elongin_A PF06881.11 KZN86831.1 - 0.0081 16.7 0.0 0.016 15.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DnaJ PF00226.31 KZN86832.1 - 2.2e-24 85.3 0.3 6e-24 83.9 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 KZN86832.1 - 7e-10 38.9 11.7 2e-09 37.5 7.2 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KZN86832.1 - 8.2e-07 29.2 5.3 8.2e-07 29.2 5.3 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KZN86832.1 - 6.7e-06 26.4 5.5 0.014 15.8 2.7 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KZN86832.1 - 3.1e-05 24.2 8.8 0.023 15.2 0.3 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KZN86832.1 - 8.7e-05 23.0 5.7 0.24 12.3 0.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger DUF4303 PF14136.6 KZN86832.1 - 0.007 16.1 0.7 0.018 14.8 0.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4303) zf-MYST PF17772.1 KZN86832.1 - 0.013 15.1 0.1 0.15 11.7 0.0 2.3 2 0 0 2 2 2 0 MYST family zinc finger domain DUF2256 PF10013.9 KZN86832.1 - 0.046 13.9 0.2 11 6.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HE PF16278.5 KZN86832.1 - 0.061 13.8 3.7 22 5.6 0.0 4.2 3 1 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger MIEAP PF16026.5 KZN86832.1 - 0.088 13.0 3.7 0.34 11.1 3.7 2.0 1 1 0 1 1 1 0 Mitochondria-eating protein LIM PF00412.22 KZN86832.1 - 0.16 12.2 3.9 6.5 7.1 0.1 2.5 2 0 0 2 2 2 0 LIM domain Cytochrome_C7 PF14522.6 KZN86832.1 - 0.33 11.0 3.6 1.1 9.3 0.9 2.5 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c Elf1 PF05129.13 KZN86832.1 - 0.37 10.9 4.3 0.68 10.0 0.9 2.4 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like R3H PF01424.22 KZN86833.1 - 2.2e-14 53.2 0.1 4.4e-14 52.2 0.1 1.5 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 KZN86833.1 - 5.3e-10 39.0 0.3 1e-09 38.1 0.3 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KZN86833.1 - 0.00024 21.1 0.3 0.00068 19.7 0.3 1.8 1 0 0 1 1 1 1 G-patch domain Peptidase_C54 PF03416.19 KZN86834.1 - 5.9e-53 180.1 0.0 2.2e-44 151.9 0.0 2.1 1 1 1 2 2 2 2 Peptidase family C54 Histone PF00125.24 KZN86835.1 - 3.6e-21 75.9 0.3 4.4e-21 75.6 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KZN86835.1 - 0.00029 21.1 1.1 0.0004 20.6 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KZN86835.1 - 0.0005 20.5 0.0 0.00083 19.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KZN86835.1 - 0.036 13.7 0.1 0.082 12.5 0.1 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain Histone_H2A_C PF16211.5 KZN86836.1 - 4.5e-21 74.3 2.6 8e-21 73.5 2.6 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KZN86836.1 - 6.6e-17 62.1 0.0 8.9e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KZN86836.1 - 9.5e-06 25.8 0.0 1.3e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Complex1_LYR PF05347.15 KZN86837.1 - 3.6e-10 39.7 0.5 4.9e-10 39.3 0.5 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) 2-oxoacid_dh PF00198.23 KZN86838.1 - 2e-79 266.4 0.0 2.6e-79 265.9 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KZN86838.1 - 1.1e-17 63.7 1.3 2.1e-17 62.7 1.3 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 KZN86838.1 - 0.0051 17.5 0.1 1 10.1 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 KZN86838.1 - 0.0054 16.5 0.1 0.093 12.6 0.1 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like Ribosomal_60s PF00428.19 KZN86838.1 - 0.017 15.7 2.0 0.017 15.7 2.0 2.9 1 1 1 2 2 2 0 60s Acidic ribosomal protein RnfC_N PF13375.6 KZN86838.1 - 0.04 13.9 0.2 0.5 10.4 0.0 2.4 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 KZN86838.1 - 0.041 13.8 0.3 0.085 12.8 0.3 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein DUF2052 PF09747.9 KZN86838.1 - 3.5 7.7 7.2 5.3 7.1 7.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) PCMT PF01135.19 KZN86840.1 - 3.4e-63 213.2 0.0 4.6e-63 212.8 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KZN86840.1 - 1.8e-08 34.3 0.0 2.9e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN86840.1 - 4.6e-07 30.4 0.0 8.8e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KZN86840.1 - 4.1e-06 26.9 0.0 6.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN86840.1 - 0.00036 21.1 0.0 0.00062 20.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN86840.1 - 0.00046 20.1 0.0 0.00063 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KZN86840.1 - 0.0017 18.0 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 KZN86840.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 KZN86840.1 - 0.04 14.7 0.0 0.069 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.10 KZN86840.1 - 0.045 13.4 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Ubie_methyltran PF01209.18 KZN86840.1 - 0.061 12.6 0.0 0.086 12.2 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KZN86840.1 - 0.062 12.7 0.0 0.088 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 KZN86840.1 - 0.064 13.2 0.0 0.099 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 KZN86840.1 - 0.12 12.4 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.20 KZN86840.1 - 0.17 11.1 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RrnaAD PF00398.20 KZN86840.1 - 0.19 10.7 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DnaJ PF00226.31 KZN86841.1 - 2.2e-22 78.9 3.2 2e-21 75.8 1.0 2.7 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 KZN86841.1 - 5.8e-18 63.5 0.6 0.11 12.7 0.0 8.1 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 KZN86841.1 - 8.8e-18 63.3 0.0 0.00054 19.7 0.0 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 KZN86841.1 - 4.2e-11 42.2 1.8 0.48 10.8 0.0 7.2 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KZN86841.1 - 1.6e-10 41.4 13.1 3.2e-05 24.4 1.7 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 KZN86841.1 - 3e-10 40.1 10.4 0.0005 20.2 0.2 5.2 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 KZN86841.1 - 3e-10 40.0 13.6 0.066 14.1 0.0 7.9 4 3 4 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 KZN86841.1 - 1.3e-07 31.8 5.0 41 5.1 0.0 8.1 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 KZN86841.1 - 1.9e-05 24.7 0.7 0.24 11.8 0.0 5.7 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KZN86841.1 - 0.00017 21.2 0.0 1.5 8.6 0.0 4.0 3 1 1 4 4 4 2 TPR repeat HrpB1_HrpK PF09613.10 KZN86841.1 - 0.0003 20.4 4.1 0.32 10.6 0.9 3.0 2 1 1 3 3 3 2 Bacterial type III secretion protein (HrpB1_HrpK) PknG_TPR PF16918.5 KZN86841.1 - 0.00036 19.4 0.4 0.013 14.3 0.0 2.7 3 0 0 3 3 3 1 Protein kinase G tetratricopeptide repeat TPR_7 PF13176.6 KZN86841.1 - 0.00074 19.4 5.1 32 4.9 0.0 6.4 5 2 1 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KZN86841.1 - 0.0043 17.2 10.6 1.1 9.5 0.3 5.2 3 2 2 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 YfiO PF13525.6 KZN86841.1 - 0.012 15.4 1.6 0.17 11.6 0.3 2.9 2 1 0 2 2 2 0 Outer membrane lipoprotein RPT PF13446.6 KZN86841.1 - 0.014 15.3 0.0 0.45 10.5 0.0 3.1 2 1 0 2 2 2 0 A repeated domain in UCH-protein TPR_16 PF13432.6 KZN86841.1 - 0.088 13.5 19.4 5.6 7.7 0.0 6.8 7 2 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 KZN86841.1 - 0.2 11.6 3.5 1.7e+02 2.3 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat PCRF PF03462.18 KZN86842.1 - 9.1e-48 162.7 0.0 5.5e-47 160.1 0.0 2.1 3 0 0 3 3 3 1 PCRF domain RF-1 PF00472.20 KZN86842.1 - 2.2e-33 114.6 1.1 4.7e-33 113.6 1.1 1.5 1 0 0 1 1 1 1 RF-1 domain Wtap PF17098.5 KZN86842.1 - 0.041 13.8 0.2 0.39 10.6 0.1 2.4 2 1 1 3 3 3 0 WTAP/Mum2p family Phage_tail_T PF06223.12 KZN86842.1 - 0.099 13.2 0.1 0.44 11.1 0.0 2.0 2 0 0 2 2 2 0 Minor tail protein T MIR PF02815.19 KZN86842.1 - 0.14 12.0 0.1 0.23 11.3 0.1 1.3 1 0 0 1 1 1 0 MIR domain Mito_carr PF00153.27 KZN86843.1 - 4.5e-50 167.5 5.3 8.6e-21 73.7 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein DEAD PF00270.29 KZN86844.1 - 1.1e-42 145.8 0.0 1.6e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KZN86844.1 - 6e-28 97.4 0.7 8.1e-27 93.8 0.5 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KZN86844.1 - 0.0076 16.3 0.0 0.018 15.1 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SMC_N PF02463.19 KZN86845.1 - 1.3e-19 70.5 13.7 7.3e-19 68.1 13.7 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KZN86845.1 - 9.6e-12 45.8 30.4 9.6e-12 45.8 30.4 5.3 2 2 1 3 3 3 1 AAA domain AAA_15 PF13175.6 KZN86845.1 - 1.3e-11 44.9 3.4 1.3e-11 44.9 3.4 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KZN86845.1 - 9.5e-10 38.8 1.9 1.3e-06 28.5 0.3 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KZN86845.1 - 0.00014 21.5 0.0 0.00034 20.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain TPR_MLP1_2 PF07926.12 KZN86845.1 - 0.0011 19.0 19.0 0.0011 19.0 19.0 6.5 4 2 1 5 5 5 1 TPR/MLP1/MLP2-like protein SbcCD_C PF13558.6 KZN86845.1 - 0.017 15.4 0.2 0.12 12.7 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 KZN86845.1 - 0.11 13.1 0.2 0.11 13.1 0.2 5.4 3 2 0 3 3 3 0 ABC transporter DTHCT PF08070.11 KZN86845.1 - 2 9.2 14.2 0.11 13.3 2.3 3.3 2 0 0 2 2 2 0 DTHCT (NUC029) region PAP_assoc PF03828.19 KZN86846.1 - 0.00088 19.4 0.0 0.0072 16.5 0.0 2.4 1 1 0 1 1 1 1 Cid1 family poly A polymerase Glyco_transf_20 PF00982.21 KZN86847.1 - 2e-150 501.6 0.0 3.8e-150 500.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KZN86847.1 - 4.3e-83 278.0 0.0 7.5e-83 277.2 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase MFS_1 PF07690.16 KZN86848.1 - 6.4e-17 61.5 56.9 1.9e-15 56.7 45.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PP28 PF10252.9 KZN86849.1 - 1.2e-28 99.4 19.2 1.2e-28 99.4 19.2 3.2 3 0 0 3 3 3 1 Casein kinase substrate phosphoprotein PP28 YL1 PF05764.13 KZN86849.1 - 0.095 12.8 35.4 0.13 12.4 35.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein UNC-50 PF05216.13 KZN86850.1 - 7.9e-84 280.6 7.1 9.5e-84 280.4 7.1 1.0 1 0 0 1 1 1 1 UNC-50 family Sec7 PF01369.20 KZN86851.1 - 5e-27 94.8 0.0 1.4e-26 93.3 0.0 1.7 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KZN86851.1 - 7.7e-20 71.5 0.1 2.2e-18 66.8 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain Tektin PF03148.14 KZN86851.1 - 0.081 11.7 0.3 0.13 11.0 0.3 1.2 1 0 0 1 1 1 0 Tektin family Cnn_1N PF07989.11 KZN86852.1 - 7.1e-23 80.6 10.4 7.1e-23 80.6 10.4 12.3 9 1 4 13 13 13 2 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 KZN86852.1 - 3.4e-22 78.5 29.0 8.8e-18 64.4 16.8 12.1 11 2 1 13 13 13 2 Micro-tubular organiser Mto1 C-term Mto2-binding region Orthopox_A36R PF05950.11 KZN86852.1 - 0.00075 19.7 0.5 0.0024 18.0 0.5 1.9 1 0 0 1 1 1 1 Orthopoxvirus A36R protein QRPTase_C PF01729.19 KZN86853.1 - 5.7e-48 162.9 0.3 2.3e-46 157.7 0.3 2.0 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KZN86853.1 - 1.3e-22 79.6 0.0 3.3e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Ribul_P_3_epim PF00834.19 KZN86853.1 - 0.11 11.8 0.0 0.49 9.7 0.0 2.0 1 1 2 3 3 3 0 Ribulose-phosphate 3 epimerase family Aldose_epim PF01263.20 KZN86854.1 - 1e-60 205.6 0.0 1.1e-60 205.4 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Zn_clus PF00172.18 KZN86855.1 - 9.8e-09 35.2 13.2 1.6e-08 34.5 13.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ras PF00071.22 KZN86856.1 - 2.4e-28 98.7 0.0 6.1e-27 94.2 0.0 2.1 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KZN86856.1 - 0.00023 21.4 0.0 0.00071 19.8 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KZN86856.1 - 0.09 12.3 0.0 0.27 10.7 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Arf PF00025.21 KZN86856.1 - 0.18 11.3 0.0 0.39 10.2 0.0 1.5 2 0 0 2 2 2 0 ADP-ribosylation factor family PAS_9 PF13426.7 KZN86857.1 - 3.8e-26 91.4 0.0 3.7e-19 68.9 0.0 3.4 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.12 KZN86857.1 - 7.6e-19 67.8 0.0 1.6e-11 44.4 0.0 3.9 4 0 0 4 4 4 3 PAS fold GATA PF00320.27 KZN86857.1 - 1.8e-14 53.0 7.0 4.6e-14 51.7 7.0 1.8 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 KZN86857.1 - 6.7e-12 45.4 0.0 0.00074 19.5 0.0 3.7 3 1 0 3 3 3 2 PAS fold PAS_4 PF08448.10 KZN86857.1 - 9.6e-08 32.3 0.0 0.0083 16.4 0.0 3.9 4 0 0 4 4 4 2 PAS fold PAS_11 PF14598.6 KZN86857.1 - 0.00057 20.0 0.0 0.086 13.0 0.0 3.3 3 0 0 3 3 3 1 PAS domain PAS_8 PF13188.7 KZN86857.1 - 0.0044 17.0 0.0 0.14 12.2 0.0 2.4 2 0 0 2 2 2 1 PAS domain LETM1 PF07766.13 KZN86858.1 - 3.1e-09 36.6 0.0 1.8e-06 27.5 0.0 2.3 1 1 0 1 1 1 1 LETM1-like protein Nrap_D4 PF17405.2 KZN86859.1 - 1.1e-62 211.2 0.1 2.4e-62 210.1 0.1 1.6 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 KZN86859.1 - 4e-57 192.5 0.9 8.3e-57 191.5 0.9 1.6 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 KZN86859.1 - 1.9e-48 164.1 0.0 3.1e-46 156.9 0.0 2.5 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap_D3 PF17404.2 KZN86859.1 - 4.1e-45 153.7 0.1 9.4e-45 152.6 0.1 1.6 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap PF03813.14 KZN86859.1 - 1.3e-38 132.5 1.7 1.3e-38 132.5 0.0 1.9 2 0 0 2 2 2 1 Nrap protein domain 1 Nrap_D6 PF17407.2 KZN86859.1 - 4.6e-29 101.4 0.0 1.1e-28 100.2 0.0 1.7 1 0 0 1 1 1 1 Nrap protein domain 6 Cys_Met_Meta_PP PF01053.20 KZN86860.1 - 1.4e-27 96.2 0.0 2.9e-18 65.6 0.0 2.1 1 1 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KZN86860.1 - 0.00039 19.7 0.0 0.00063 19.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II SoPB_HTH PF18090.1 KZN86860.1 - 0.041 14.0 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 Centromere-binding protein HTH domain MRP-L20 PF12824.7 KZN86862.1 - 2.5e-62 209.9 4.1 2.8e-62 209.7 4.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 KZN86862.1 - 0.0033 17.5 0.0 0.006 16.6 0.0 1.4 1 0 0 1 1 1 1 Neugrin HTH_32 PF13565.6 KZN86862.1 - 0.0046 17.5 0.7 0.25 12.0 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain CtsR PF05848.11 KZN86862.1 - 0.098 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 CtsR N-terminal HTH domain Peptidase_M20 PF01546.28 KZN86863.1 - 3.8e-31 108.4 0.0 4.8e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KZN86863.1 - 5.3e-13 48.8 0.0 8.2e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KZN86863.1 - 0.055 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M28 PLDc PF00614.22 KZN86864.1 - 1.6e-14 53.4 0.1 1.3e-06 28.3 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KZN86864.1 - 2.2e-13 50.3 0.0 1.4e-06 28.2 0.0 2.9 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 KZN86864.1 - 8.4e-07 29.0 0.2 5.8e-06 26.3 0.0 2.6 2 1 0 2 2 2 1 PX domain DUF313 PF03754.13 KZN86864.1 - 0.15 12.3 0.1 0.55 10.5 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF313) Abhydrolase_6 PF12697.7 KZN86865.1 - 0.016 15.9 0.0 0.02 15.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KZN86865.1 - 0.071 12.7 0.0 0.65 9.6 0.0 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KZN86865.1 - 0.081 12.2 0.0 0.6 9.3 0.0 2.2 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Ribosomal_L27A PF00828.19 KZN86866.1 - 2.5e-22 79.9 0.0 3.4e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Helicase_C_2 PF13307.6 KZN86867.1 - 2.8e-56 190.4 0.0 6.7e-56 189.1 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 KZN86867.1 - 1.1e-49 168.4 0.0 2.3e-49 167.4 0.0 1.6 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 KZN86867.1 - 0.0085 15.8 0.0 0.023 14.4 0.0 1.7 2 0 0 2 2 2 1 Helical and beta-bridge domain ResIII PF04851.15 KZN86867.1 - 0.0097 15.9 0.1 2.5 8.1 0.0 2.8 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit Methyltrn_RNA_4 PF09936.9 KZN86867.1 - 0.32 10.8 2.1 3.9 7.3 0.0 2.9 3 0 0 3 3 3 0 SAM-dependent RNA methyltransferase Sel1 PF08238.12 KZN86868.1 - 6.9e-18 64.7 15.3 4.7e-07 30.3 0.0 6.7 7 0 0 7 7 7 4 Sel1 repeat TPR_1 PF00515.28 KZN86868.1 - 0.00021 21.0 0.1 0.0012 18.5 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KZN86868.1 - 0.033 15.0 1.7 0.14 13.0 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KZN86868.1 - 0.1 12.8 0.0 0.1 12.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TBPIP PF07106.13 KZN86869.1 - 0.0032 17.4 0.3 0.007 16.3 0.1 1.7 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain PspA_IM30 PF04012.12 KZN86869.1 - 0.014 15.0 4.6 0.071 12.7 2.7 2.1 1 1 1 2 2 2 0 PspA/IM30 family CCDC-167 PF15188.6 KZN86869.1 - 0.025 14.9 8.9 0.88 9.9 0.4 2.5 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF4407 PF14362.6 KZN86869.1 - 0.028 13.8 0.7 0.037 13.4 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4140 PF13600.6 KZN86869.1 - 0.029 14.8 6.0 0.24 11.9 1.0 2.9 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Uds1 PF15456.6 KZN86869.1 - 0.064 13.4 9.2 0.037 14.2 7.0 1.7 1 1 1 2 2 2 0 Up-regulated During Septation DUF3106 PF11304.8 KZN86869.1 - 0.07 13.6 3.4 0.093 13.2 2.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) Phosphodiest PF01663.22 KZN86869.1 - 0.097 12.2 0.2 0.17 11.4 0.1 1.4 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Penicillinase_R PF03965.16 KZN86869.1 - 0.11 12.9 0.7 0.45 10.9 0.1 2.1 1 1 1 2 2 2 0 Penicillinase repressor DUF1192 PF06698.11 KZN86869.1 - 0.17 12.0 8.2 3.3 7.8 2.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Leu_zip PF15294.6 KZN86869.1 - 0.41 10.1 5.3 0.48 9.9 3.1 1.8 1 1 1 2 2 2 0 Leucine zipper ABC_tran_CTD PF16326.5 KZN86869.1 - 0.6 10.4 12.2 1 9.7 2.6 2.8 1 1 1 2 2 2 0 ABC transporter C-terminal domain APG6_N PF17675.1 KZN86869.1 - 0.92 10.0 11.9 4.6 7.8 11.9 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region Siah-Interact_N PF09032.11 KZN86869.1 - 1.8 8.9 7.1 3.6 8.0 0.5 2.8 1 1 2 3 3 3 0 Siah interacting protein, N terminal ZapB PF06005.12 KZN86869.1 - 7.4 7.1 10.9 12 6.4 3.9 2.5 1 1 1 2 2 2 0 Cell division protein ZapB zf-CCCH PF00642.24 KZN86870.1 - 3.3e-12 46.0 10.4 2.4e-06 27.3 1.9 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KZN86870.1 - 2.5e-10 39.9 9.0 1.5e-06 27.9 2.0 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 KZN86870.1 - 3.2e-09 37.4 5.0 0.0003 21.4 0.4 2.5 1 1 1 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KZN86870.1 - 3.2e-09 36.5 16.1 4.2e-05 23.5 1.8 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 KZN86870.1 - 0.00052 20.2 0.2 0.00091 19.4 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KZN86870.1 - 0.0029 18.0 13.9 0.18 12.3 3.2 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Bromodomain PF00439.25 KZN86871.1 - 4.7e-13 49.0 0.1 7e-13 48.5 0.1 1.2 1 0 0 1 1 1 1 Bromodomain OTU PF02338.19 KZN86872.1 - 1.9e-07 31.7 0.0 3e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease UN_NPL4 PF11543.8 KZN86872.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Peptidase_C65 PF10275.9 KZN86872.1 - 0.14 11.5 0.0 1.8 8.0 0.0 2.2 1 1 1 2 2 2 0 Peptidase C65 Otubain Pkinase PF00069.25 KZN86873.1 - 2.7e-42 145.0 0.0 1.8e-38 132.4 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KZN86873.1 - 1.2e-08 34.5 0.0 0.0012 18.2 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KZN86873.1 - 0.0018 18.3 0.1 1.1 9.1 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KZN86873.1 - 0.007 15.2 0.0 0.0091 14.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KZN86873.1 - 0.083 12.2 0.0 11 5.2 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 KZN86873.1 - 0.11 11.8 0.2 2.3 7.5 0.0 2.5 2 1 1 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cnd1_N PF12922.7 KZN86874.1 - 1e-59 201.2 0.0 2.3e-59 200.0 0.0 1.7 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 KZN86874.1 - 1.1e-48 165.3 2.2 3.4e-43 147.5 0.4 3.2 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KZN86874.1 - 1.7e-11 44.3 1.1 5e-06 26.8 0.0 4.0 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.22 KZN86874.1 - 1.4e-08 34.3 10.8 0.059 13.7 0.0 6.6 5 1 2 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 KZN86874.1 - 1.4e-05 25.5 12.5 0.19 12.3 0.1 6.4 7 0 0 7 7 7 2 HEAT-like repeat Adaptin_N PF01602.20 KZN86874.1 - 1.8e-05 23.5 11.9 0.0027 16.4 0.5 4.2 4 2 0 4 4 4 2 Adaptin N terminal region RTP1_C1 PF10363.9 KZN86874.1 - 3.9e-05 23.8 0.2 0.055 13.7 0.0 3.6 3 1 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 KZN86874.1 - 8e-05 22.0 2.2 0.00039 19.7 0.7 2.7 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain FlbD PF06289.11 KZN86874.1 - 0.058 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Flagellar and Swarming motility proteins Oxysterol_BP PF01237.18 KZN86875.1 - 2.6e-55 187.8 0.0 3.6e-46 157.7 0.0 2.1 1 1 1 2 2 2 2 Oxysterol-binding protein Peptidase_C12 PF01088.21 KZN86876.1 - 7.1e-62 208.9 0.0 1.1e-61 208.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KZN86876.1 - 0.00057 19.7 0.3 0.0016 18.3 0.3 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases P4Ha_N PF08336.11 KZN86876.1 - 0.066 13.2 0.4 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region I-set PF07679.16 KZN86877.1 - 1.5e-06 28.2 1.0 0.026 14.6 0.0 5.0 6 0 0 6 6 6 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KZN86877.1 - 0.0039 17.8 0.0 1.5 9.5 0.0 4.3 4 0 0 4 4 4 1 Immunoglobulin domain Arylesterase PF01731.20 KZN86878.1 - 0.00034 20.8 0.0 0.0036 17.4 0.0 2.6 2 1 0 2 2 2 1 Arylesterase N_BRCA1_IG PF16158.5 KZN86879.1 - 3.1e-32 111.3 0.0 8.1e-32 110.0 0.0 1.8 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 KZN86879.1 - 9.3e-24 83.0 54.4 1.7e-08 34.1 4.5 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type C1_2 PF03107.16 KZN86879.1 - 1.4 9.3 53.9 0.11 12.8 9.9 4.5 4 0 0 4 4 4 0 C1 domain Btz PF09405.10 KZN86880.1 - 2.5e-30 105.4 4.0 2.5e-30 105.4 4.0 2.0 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding RRM_1 PF00076.22 KZN86881.1 - 9.4e-26 89.4 0.5 2.3e-14 53.0 0.1 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KZN86881.1 - 1.5e-05 25.0 0.0 0.024 14.8 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif SPT6_acidic PF14632.6 KZN86881.1 - 0.017 15.7 2.1 0.017 15.7 2.1 3.6 3 1 0 3 3 3 0 Acidic N-terminal SPT6 Nup35_RRM_2 PF14605.6 KZN86881.1 - 0.14 12.2 0.1 4.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF1676 PF07898.13 KZN86881.1 - 0.23 11.5 3.5 0.6 10.1 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) RPA43_OB PF17875.1 KZN86881.1 - 3.8 8.1 14.0 2.9 8.5 1.5 3.2 3 1 1 4 4 4 0 RPA43 OB domain in RNA Pol I Ino80_Iec3 PF14612.6 KZN86882.1 - 2.5e-81 273.9 3.4 4e-81 273.2 3.4 1.3 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling ECR1_N PF14382.6 KZN86883.1 - 2.4e-16 59.2 0.8 4.6e-16 58.3 0.8 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KZN86883.1 - 0.0035 17.7 0.4 0.0068 16.7 0.4 1.5 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 KZN86883.1 - 0.056 14.1 1.6 1.7 9.3 0.1 2.9 3 0 0 3 3 3 0 Exosome component EXOSC1/CSL4 IFRD PF05004.13 KZN86884.1 - 8.7e-90 300.9 0.9 1.2e-89 300.5 0.9 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Cnd3 PF12719.7 KZN86884.1 - 0.013 14.7 2.4 0.026 13.7 0.0 2.3 1 1 2 3 3 3 0 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KZN86884.1 - 0.016 15.6 0.1 2.4 8.6 0.0 2.9 2 0 0 2 2 2 0 HEAT repeats HEAT PF02985.22 KZN86884.1 - 0.02 15.1 0.5 11 6.6 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat Oxysterol_BP PF01237.18 KZN86885.1 - 4.7e-120 400.8 0.2 3.5e-119 398.0 0.0 2.4 3 1 0 3 3 3 1 Oxysterol-binding protein PH_8 PF15409.6 KZN86885.1 - 1.9e-38 130.6 0.1 3.8e-38 129.7 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KZN86885.1 - 3.2e-08 34.0 0.5 2.9e-07 31.0 0.0 2.7 3 0 0 3 3 3 1 PH domain PH_11 PF15413.6 KZN86885.1 - 0.0014 19.0 2.5 0.15 12.5 0.1 2.8 2 1 1 3 3 3 2 Pleckstrin homology domain SH2_2 PF14633.6 KZN86886.1 - 1.3e-86 289.4 0.0 3.2e-86 288.2 0.0 1.7 1 0 0 1 1 1 1 SH2 domain HTH_44 PF14641.6 KZN86886.1 - 6.1e-36 123.3 1.2 1.7e-35 121.9 1.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 KZN86886.1 - 3.9e-31 107.5 0.0 7.5e-31 106.6 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 KZN86886.1 - 1.7e-27 96.1 0.0 4.7e-27 94.6 0.0 1.8 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 KZN86886.1 - 1.2e-16 61.0 17.4 1.2e-16 61.0 17.4 5.9 4 3 2 6 6 4 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 KZN86886.1 - 4.7e-08 33.8 2.7 1.5e-06 29.0 2.7 3.5 1 1 0 1 1 1 1 HHH domain SH2 PF00017.24 KZN86886.1 - 0.0001 22.3 0.0 0.00028 20.9 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.7 KZN86886.1 - 0.00027 21.1 0.0 0.00075 19.7 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif Tex_N PF09371.10 KZN86886.1 - 0.0057 16.3 7.5 0.056 13.1 0.0 4.1 4 0 0 4 4 4 1 Tex-like protein N-terminal domain ATP-synt_B PF00430.18 KZN86886.1 - 0.012 15.7 0.4 1.6 8.9 0.2 2.9 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) B12-binding PF02310.19 KZN86886.1 - 0.14 12.2 0.0 0.5 10.4 0.0 1.9 2 0 0 2 2 2 0 B12 binding domain Pkinase PF00069.25 KZN86887.1 - 6e-65 219.2 0.0 7.6e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN86887.1 - 4.5e-36 124.5 0.0 6.1e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KZN86887.1 - 5.9e-06 25.3 0.0 1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KZN86887.1 - 8.8e-05 21.9 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KZN86887.1 - 0.028 13.5 0.0 0.042 12.9 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 KZN86887.1 - 0.056 12.4 0.0 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KZN86887.1 - 0.073 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KZN86887.1 - 0.14 12.0 0.0 0.47 10.3 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Abhydrolase_9_N PF15420.6 KZN86888.1 - 0.011 15.8 0.9 0.025 14.6 0.9 1.6 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus HUN PF08729.10 KZN86889.1 - 1.5e-07 31.3 0.1 4e-07 29.9 0.1 1.8 1 0 0 1 1 1 1 HPC2 and ubinuclein domain RPAP1_C PF08620.10 KZN86890.1 - 1.9e-24 85.6 0.0 3.2e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KZN86890.1 - 1.3e-18 66.5 9.6 5.7e-18 64.4 9.3 2.1 2 0 0 2 2 2 1 RPAP1-like, N-terminal Cgr1 PF03879.14 KZN86890.1 - 0.091 13.1 0.8 0.15 12.5 0.8 1.2 1 0 0 1 1 1 0 Cgr1 family ANAPC1 PF12859.7 KZN86892.1 - 1.2e-31 109.9 0.7 4.5e-31 108.1 0.7 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 KZN86892.1 - 0.013 15.9 11.5 0.81 10.2 0.0 4.4 5 0 0 5 5 5 0 Proteasome/cyclosome repeat eIF2A PF08662.11 KZN86893.1 - 2.6e-81 272.1 0.0 2.1e-80 269.2 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KZN86893.1 - 0.00092 20.0 0.3 0.18 12.7 0.1 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat TolA_bind_tri PF16331.5 KZN86895.1 - 0.093 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation Acetyltransf_13 PF13880.6 KZN86896.1 - 4.7e-29 100.2 0.0 1e-28 99.1 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 KZN86896.1 - 1.4e-14 53.6 0.3 2.4e-14 52.8 0.3 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO EMG1 PF03587.14 KZN86897.1 - 4.6e-80 267.9 0.1 5.4e-80 267.6 0.1 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Glyoxalase PF00903.25 KZN86898.1 - 0.0097 16.1 0.0 0.025 14.7 0.0 1.7 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Gly-zipper_Omp PF13488.6 KZN86898.1 - 0.054 13.5 5.1 0.11 12.5 5.1 1.4 1 0 0 1 1 1 0 Glycine zipper Rick_17kDa_Anti PF05433.15 KZN86898.1 - 0.22 11.4 6.4 0.53 10.2 6.4 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.6 KZN86898.1 - 0.32 10.8 6.2 0.81 9.5 6.2 1.6 1 0 0 1 1 1 0 Glycine-zipper domain UQ_con PF00179.26 KZN86899.1 - 1.8e-52 176.7 0.0 2e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KZN86899.1 - 0.0047 16.6 0.0 0.0059 16.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KZN86899.1 - 0.036 14.3 0.0 0.045 14.0 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 KZN86899.1 - 0.045 13.6 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain Acyl-CoA_dh_N PF02771.16 KZN86900.1 - 1.2e-28 100.0 0.1 2.6e-28 98.9 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KZN86900.1 - 2.5e-25 89.4 1.4 4.8e-25 88.5 1.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KZN86900.1 - 1.2e-16 60.7 0.0 2.2e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KZN86900.1 - 1.4e-07 31.8 1.5 1.4e-07 31.8 1.5 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Fungal_trans PF04082.18 KZN86901.1 - 0.00082 18.5 0.1 0.0018 17.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN86901.1 - 0.089 12.9 0.8 0.15 12.2 0.8 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RNase_J_C PF17770.1 KZN86901.1 - 0.2 12.7 0.0 3 9.0 0.0 2.8 3 0 0 3 3 3 0 Ribonuclease J C-terminal domain XPG_I PF00867.18 KZN86902.1 - 1.9e-30 105.0 1.3 4.3e-30 103.9 0.0 2.2 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 KZN86902.1 - 2.2e-27 95.5 0.3 9.9e-27 93.4 0.0 2.3 2 1 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KZN86902.1 - 9e-05 23.0 0.2 0.00063 20.3 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 KZN86902.1 - 0.14 12.3 0.0 0.4 10.8 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif SET PF00856.28 KZN86902.1 - 1.1 9.7 2.9 1.6 9.1 2.5 1.8 1 1 0 1 1 1 0 SET domain Linker_histone PF00538.19 KZN86903.1 - 4.7e-31 107.0 0.5 4.7e-31 107.0 0.5 1.9 2 0 0 2 2 2 1 linker histone H1 and H5 family PIP5K PF01504.18 KZN86904.1 - 1.3e-101 339.4 0.0 1.3e-101 339.4 0.0 1.9 3 0 0 3 3 3 1 Phosphatidylinositol-4-phosphate 5-Kinase TFIID_20kDa PF03847.13 KZN86905.1 - 6.4e-21 74.6 0.0 1.1e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.24 KZN86905.1 - 0.0042 17.5 0.0 0.0042 17.5 0.0 3.2 4 0 0 4 4 4 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KZN86905.1 - 0.059 13.7 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF4407 PF14362.6 KZN86905.1 - 4.8 6.5 18.3 2.5 7.4 11.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Kelch_5 PF13854.6 KZN86906.1 - 0.0022 18.0 2.9 0.057 13.4 0.1 3.5 3 0 0 3 3 3 1 Kelch motif MGC-24 PF05283.11 KZN86906.1 - 0.077 13.4 0.2 0.077 13.4 0.2 1.7 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF5305 PF17231.2 KZN86906.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Syndecan PF01034.20 KZN86906.1 - 0.19 11.7 0.0 0.39 10.7 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain DASH_Spc34 PF08657.10 KZN86907.1 - 3e-42 145.2 0.3 1.2e-21 77.7 0.0 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 DASH_Spc19 PF08287.11 KZN86907.1 - 0.0033 17.3 0.1 0.0067 16.3 0.1 1.5 1 0 0 1 1 1 1 Spc19 DUF3381 PF11861.8 KZN86907.1 - 0.031 14.1 0.2 0.17 11.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Rpn3_C PF08375.11 KZN86908.1 - 6.1e-27 93.8 1.2 1.9e-26 92.2 1.2 1.9 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 KZN86908.1 - 1.2e-19 70.7 0.3 7.6e-19 68.2 0.0 2.3 2 0 0 2 2 2 1 PCI domain ABATE PF07336.11 KZN86908.1 - 0.03 15.0 2.1 0.82 10.3 0.1 2.4 2 0 0 2 2 2 0 Putative stress-induced transcription regulator Sigma70_r1_2 PF00140.20 KZN86908.1 - 1.3 9.1 5.2 1 9.5 2.4 2.2 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 polyprenyl_synt PF00348.17 KZN86909.1 - 4.7e-72 242.1 0.0 9.6e-72 241.1 0.0 1.5 1 1 0 1 1 1 1 Polyprenyl synthetase MMM1 PF10296.9 KZN86910.1 - 0.00013 21.1 0.0 0.00024 20.3 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 PH_11 PF15413.6 KZN86910.1 - 0.094 13.1 0.0 0.32 11.4 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain EURL PF06937.11 KZN86910.1 - 0.16 11.3 0.2 0.32 10.4 0.2 1.4 1 0 0 1 1 1 0 EURL protein ANTH PF07651.16 KZN86911.1 - 3.5e-79 265.7 0.0 3.5e-79 265.7 0.0 2.8 2 1 1 3 3 3 1 ANTH domain I_LWEQ PF01608.17 KZN86911.1 - 1.9e-55 187.3 4.9 1.9e-55 187.3 4.9 6.4 4 2 3 7 7 7 2 I/LWEQ domain MATalpha_HMGbox PF04769.12 KZN86912.1 - 3e-27 95.3 0.0 4e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box PARP PF00644.20 KZN86914.1 - 3.4e-11 43.1 0.1 6.6e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 KZN86914.1 - 1.1e-07 31.5 0.0 3.5e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme DUF1263 PF06882.12 KZN86915.1 - 0.065 13.3 0.3 0.18 11.9 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1263) Complex1_LYR PF05347.15 KZN86916.1 - 2.5e-16 59.5 5.0 2.5e-16 59.5 5.0 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KZN86916.1 - 3.4e-05 24.5 1.3 3.9e-05 24.3 1.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like VitD-bind_III PF09164.10 KZN86916.1 - 0.062 13.3 0.1 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 Vitamin D binding protein, domain III DASH_Spc19 PF08287.11 KZN86917.1 - 0.1 12.5 2.6 0.36 10.7 0.0 2.8 3 0 0 3 3 3 0 Spc19 EVI2A PF05399.11 KZN86918.1 - 0.013 15.2 7.0 0.1 12.1 0.0 3.1 3 0 0 3 3 3 0 Ectropic viral integration site 2A protein (EVI2A) EGF PF00008.27 KZN86918.1 - 0.24 11.8 6.8 0.42 10.9 6.8 1.4 1 0 0 1 1 1 0 EGF-like domain Baculo_11_kDa PF06143.11 KZN86918.1 - 0.69 9.5 1.7 1.4 8.6 1.7 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family ATP-sulfurylase PF01747.17 KZN86919.1 - 5.5e-86 287.4 0.0 8e-86 286.9 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 KZN86919.1 - 2.2e-60 203.1 0.0 3.5e-60 202.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 KZN86919.1 - 6.9e-53 178.6 0.0 1.2e-52 177.8 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain AAA_18 PF13238.6 KZN86919.1 - 0.042 14.4 0.0 0.1 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain SET PF00856.28 KZN86920.1 - 9.3e-12 45.7 0.1 9.3e-12 45.7 0.1 3.6 3 1 0 3 3 3 1 SET domain AWS PF17907.1 KZN86920.1 - 1.7e-08 34.3 9.3 1.7e-08 34.3 9.3 2.7 3 0 0 3 3 3 1 AWS domain BAF1_ABF1 PF04684.13 KZN86920.1 - 0.0042 16.2 2.7 0.0042 16.2 2.7 2.3 2 1 0 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor DHHC PF01529.20 KZN86921.1 - 3.6e-34 117.8 7.4 3.6e-34 117.8 7.4 1.8 2 1 0 2 2 2 1 DHHC palmitoyltransferase B12D PF06522.11 KZN86922.1 - 0.072 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit RHH_5 PF07878.11 KZN86922.1 - 0.12 12.2 0.1 0.46 10.4 0.0 1.8 2 0 0 2 2 2 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 PMT PF02366.18 KZN86923.1 - 5.1e-83 278.4 16.9 5.1e-83 278.4 16.9 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KZN86923.1 - 1.2e-66 224.1 10.2 1.2e-66 224.1 10.2 2.5 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KZN86923.1 - 3.6e-44 150.9 0.0 6.9e-44 149.9 0.0 1.4 1 0 0 1 1 1 1 MIR domain PRP21_like_P PF12230.8 KZN86924.1 - 1.4e-55 188.6 13.5 8.3e-55 186.0 13.5 1.9 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 KZN86924.1 - 3.3e-34 116.6 5.7 9.8e-17 60.7 0.5 2.6 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 KZN86924.1 - 0.0052 16.4 2.7 0.016 14.8 0.2 2.5 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 KZN86924.1 - 0.12 12.6 0.1 0.24 11.7 0.1 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Sec2p PF06428.11 KZN86925.1 - 1.1e-28 99.0 15.0 1.1e-28 99.0 15.0 1.9 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p SPATA1_C PF15743.5 KZN86925.1 - 0.0036 17.4 6.0 0.0036 17.4 6.0 2.2 1 1 1 2 2 2 1 Spermatogenesis-associated C-terminus PGDYG PF14083.6 KZN86925.1 - 0.19 12.0 0.0 0.61 10.3 0.0 1.8 2 0 0 2 2 2 0 PGDYG protein Macoilin PF09726.9 KZN86925.1 - 0.56 8.7 16.1 1 7.8 16.1 1.3 1 0 0 1 1 1 0 Macoilin family GCN5L1 PF06320.13 KZN86925.1 - 2 8.6 11.9 0.76 9.9 7.9 2.1 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Fib_alpha PF08702.10 KZN86925.1 - 3.5 7.8 16.2 6.4 7.0 4.7 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Mer2 PF09074.10 KZN86925.1 - 4.7 7.0 14.5 23 4.7 14.5 2.0 1 1 0 1 1 1 0 Mer2 Coq4 PF05019.13 KZN86926.1 - 1.9e-96 321.7 0.0 2.2e-96 321.4 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 DUF5345 PF17280.2 KZN86926.1 - 2.2 8.3 4.4 3.5 7.7 4.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5345) SET PF00856.28 KZN86927.1 - 8.6e-20 71.8 0.0 1.8e-19 70.8 0.0 1.5 1 0 0 1 1 1 1 SET domain DASH_Duo1 PF08651.10 KZN86927.1 - 0.27 11.1 1.2 0.84 9.5 0.2 2.1 2 0 0 2 2 2 0 DASH complex subunit Duo1 ApbA_C PF08546.11 KZN86928.1 - 3.9e-33 114.3 0.0 5.9e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KZN86928.1 - 1.3e-21 76.8 0.0 3.7e-21 75.3 0.0 1.8 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Sas10_Utp3 PF04000.15 KZN86929.1 - 2.3e-17 63.4 1.0 2.3e-17 63.4 1.0 2.5 2 1 0 2 2 2 1 Sas10/Utp3/C1D family Neur_chan_memb PF02932.16 KZN86929.1 - 3.3 7.7 6.7 4.4 7.3 6.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.7 KZN86929.1 - 8.8 4.3 17.0 11 3.9 17.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2076 PF09849.9 KZN86930.1 - 1.4e-09 38.4 16.5 1.8e-09 38.1 16.5 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 KZN86930.1 - 0.00019 21.4 1.4 0.00033 20.7 1.4 1.5 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 KZN86930.1 - 0.026 14.6 0.5 0.046 13.7 0.5 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, TFIIA PF03153.13 KZN86930.1 - 2.5 8.0 9.9 2.9 7.8 9.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 KZN86930.1 - 4 8.1 14.6 4.1 8.0 11.2 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region UBX PF00789.20 KZN86931.1 - 2.7e-10 40.3 0.0 5.9e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 UBX domain Ndc1_Nup PF09531.10 KZN86931.1 - 5.7 5.5 9.0 7 5.2 9.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SURF1 PF02104.15 KZN86932.1 - 7.7e-47 159.8 0.0 1.1e-46 159.3 0.0 1.1 1 0 0 1 1 1 1 SURF1 family CENP-T_C PF15511.6 KZN86933.1 - 1.3e-45 154.0 0.1 2e-45 153.3 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KZN86933.1 - 1.3e-07 31.9 0.1 2.2e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 KZN86933.1 - 0.026 14.9 0.1 0.077 13.4 0.0 1.8 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 CMS1 PF14617.6 KZN86934.1 - 6.7e-78 261.5 4.4 8.8e-78 261.1 4.4 1.2 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 KZN86934.1 - 0.00013 21.8 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase RNA12 PF10443.9 KZN86934.1 - 0.13 10.9 4.1 0.19 10.4 4.1 1.1 1 0 0 1 1 1 0 RNA12 protein DUF1180 PF06679.12 KZN86934.1 - 0.19 12.1 1.4 0.34 11.3 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Presenilin PF01080.17 KZN86934.1 - 9.9 4.8 5.5 12 4.5 5.5 1.1 1 0 0 1 1 1 0 Presenilin RRM_1 PF00076.22 KZN86935.1 - 2.4e-12 46.5 0.0 5.7e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.22 KZN86936.1 - 4.3e-55 185.7 0.0 4.9e-55 185.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KZN86936.1 - 4.4e-21 75.3 0.0 6.5e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KZN86936.1 - 1.5e-07 31.1 0.0 1.9e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family ABM PF03992.16 KZN86937.1 - 4.8e-13 49.0 0.0 6.2e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase YqeY PF09424.10 KZN86937.1 - 0.064 13.3 0.9 0.2 11.8 0.2 1.8 2 0 0 2 2 2 0 Yqey-like protein Zn_clus PF00172.18 KZN86938.1 - 2.9e-07 30.5 9.8 2.9e-07 30.5 9.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN86938.1 - 6.9e-06 25.3 0.0 1.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain RhoGAP PF00620.27 KZN86939.1 - 7.6e-49 165.4 0.0 3e-48 163.5 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 KZN86939.1 - 7.3e-12 45.4 2.0 1.7e-11 44.2 0.2 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain FUSC PF04632.12 KZN86939.1 - 4 5.9 5.8 5.7 5.4 5.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family V-ATPase_G_2 PF16999.5 KZN86939.1 - 5.5 7.5 14.2 6.5 7.2 4.0 3.0 2 1 1 3 3 3 0 Vacuolar (H+)-ATPase G subunit MBA1 PF07961.11 KZN86940.1 - 2.7e-07 29.9 0.0 4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 MBA1-like protein EOS1 PF12326.8 KZN86941.1 - 3.4e-12 46.6 9.5 3.4e-12 46.6 9.5 2.2 1 1 1 2 2 2 2 N-glycosylation protein SUI1 PF01253.22 KZN86942.1 - 1.4e-27 96.0 3.8 2e-27 95.5 3.8 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 GlcNAc-1_reg PF18440.1 KZN86942.1 - 0.19 12.0 0.3 0.5 10.6 0.3 1.6 2 0 0 2 2 2 0 Putative GlcNAc-1 phosphotransferase regulatory domain Med12 PF09497.10 KZN86943.1 - 6.6e-27 93.6 0.5 1.9e-26 92.2 0.5 1.9 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 ACDC PF14733.6 KZN86943.1 - 0.36 11.2 1.2 13 6.2 0.2 2.7 1 1 1 2 2 2 0 AP2-coincident C-terminal PhaP_Bmeg PF09602.10 KZN86943.1 - 0.49 10.3 1.7 1.2 9.0 0.1 2.2 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) RRM_1 PF00076.22 KZN86944.1 - 3.7e-11 42.7 0.1 7.5e-07 28.9 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CIA30 PF08547.12 KZN86945.1 - 3e-41 141.1 0.1 3.9e-26 92.0 0.1 2.2 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) SAICAR_synt PF01259.18 KZN86946.1 - 4.6e-100 334.4 0.0 5.3e-100 334.2 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase ANAPC5 PF12862.7 KZN86947.1 - 2.6e-31 107.5 5.9 2.6e-31 107.5 5.9 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_19 PF14559.6 KZN86947.1 - 0.014 15.9 0.6 3.3 8.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KZN86947.1 - 0.15 12.3 9.9 7.3 7.0 0.4 5.5 5 2 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KZN86947.1 - 0.54 10.2 2.2 38 4.3 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Zn_clus PF00172.18 KZN86948.1 - 5.8e-09 35.9 11.0 1e-08 35.1 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ring_hydroxyl_A PF00848.19 KZN86949.1 - 3.8e-27 95.7 6.7 3.8e-14 53.2 0.5 2.2 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) CorC_HlyC PF03471.17 KZN86949.1 - 0.015 15.3 0.0 0.16 12.0 0.0 2.4 2 0 0 2 2 2 0 Transporter associated domain DIPSY PF11763.8 KZN86949.1 - 0.093 12.9 0.7 0.44 10.7 0.0 2.3 2 1 1 3 3 3 0 Cell-wall adhesin ligand-binding C-terminal Glyco_tranf_2_3 PF13641.6 KZN86950.1 - 1.9e-22 80.3 0.0 3.6e-22 79.4 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KZN86950.1 - 1.9e-19 70.4 0.8 1.9e-19 70.4 0.8 3.0 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KZN86950.1 - 1e-14 54.7 0.0 1.6e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.14 KZN86950.1 - 1.1e-13 50.7 3.7 4.4e-09 35.4 0.2 2.9 2 1 1 3 3 3 2 Cellulose synthase Glyco_transf_21 PF13506.6 KZN86950.1 - 8.6e-13 48.1 0.0 1.4e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 KZN86950.1 - 0.021 13.5 0.2 0.11 11.1 0.1 2.0 2 0 0 2 2 2 0 Chitin synthase Glyco_hydro_12 PF01670.16 KZN86951.1 - 3.5e-17 63.1 3.1 5.9e-17 62.4 3.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 MFS_1 PF07690.16 KZN86952.1 - 6.6e-20 71.3 33.9 6.6e-20 71.3 33.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KZN86952.1 - 2e-07 30.8 6.3 2e-07 30.8 6.3 2.9 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 DUF2406 PF10295.9 KZN86953.1 - 1.2e-25 89.9 0.1 4.5e-25 88.1 0.1 2.0 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) DUF3602 PF12223.8 KZN86954.1 - 7.2e-21 74.6 5.7 1.6e-14 54.3 0.5 3.5 3 1 1 4 4 4 2 Protein of unknown function (DUF3602) Mito_carr PF00153.27 KZN86955.1 - 1.8e-44 149.6 6.6 1.2e-16 60.4 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CBS PF00571.28 KZN86956.1 - 6.8e-07 29.6 0.0 0.13 12.7 0.0 3.2 2 1 0 2 2 2 2 CBS domain VMA21 PF09446.10 KZN86957.1 - 3.5e-15 55.9 8.4 5.3e-15 55.3 8.4 1.3 1 0 0 1 1 1 1 VMA21-like domain ABC_membrane PF00664.23 KZN86957.1 - 0.014 15.1 0.0 0.017 14.8 0.0 1.0 1 0 0 1 1 1 0 ABC transporter transmembrane region DUF2705 PF10920.8 KZN86957.1 - 0.026 13.8 0.2 0.031 13.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2705) DUF4074 PF13293.6 KZN86957.1 - 0.13 12.5 0.1 0.21 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4074) SNF2_N PF00176.23 KZN86958.1 - 1.4e-55 188.4 0.7 2.2e-55 187.8 0.7 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KZN86958.1 - 1.2e-19 70.6 1.2 4.5e-18 65.6 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KZN86958.1 - 1.5e-09 38.1 0.0 3.3e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KZN86958.1 - 3.8e-05 23.0 0.2 0.00017 20.9 0.1 1.9 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 KZN86958.1 - 8.3e-05 22.4 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HIGH_NTase1_ass PF16581.5 KZN86958.1 - 0.0023 18.0 0.2 0.0085 16.1 0.0 2.0 2 0 0 2 2 2 1 Cytidyltransferase-related C-terminal region HHH_3 PF12836.7 KZN86958.1 - 0.068 13.4 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Dus PF01207.17 KZN86959.1 - 7.8e-43 146.7 0.0 1.9e-42 145.5 0.0 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Pyrophosphatase PF00719.19 KZN86960.1 - 1.6e-57 193.8 0.2 2.1e-57 193.4 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase MRP_L53 PF10780.9 KZN86961.1 - 4.4e-18 65.2 0.1 5.9e-18 64.8 0.1 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Sec20 PF03908.13 KZN86962.1 - 4.5e-15 55.3 1.8 4.5e-15 55.3 1.8 2.1 2 0 0 2 2 2 1 Sec20 Laminin_II PF06009.12 KZN86962.1 - 0.35 10.9 11.0 1.7 8.7 3.0 3.9 3 2 1 4 4 4 0 Laminin Domain II Rep_fac_C PF08542.11 KZN86963.1 - 1.4e-19 70.3 0.0 2.6e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 KZN86963.1 - 5.1e-15 56.1 0.0 1.6e-14 54.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KZN86963.1 - 2.9e-12 46.7 0.0 1.5e-07 31.4 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 KZN86963.1 - 4.7e-09 36.4 0.0 1.2e-08 35.1 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 KZN86963.1 - 9.7e-06 25.4 0.0 6.5e-05 22.7 0.0 2.3 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KZN86963.1 - 2.2e-05 24.9 0.1 0.00069 20.0 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_assoc_2 PF16193.5 KZN86963.1 - 5.2e-05 23.5 0.1 0.00016 22.0 0.1 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 KZN86963.1 - 6.9e-05 23.1 0.0 0.00062 20.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KZN86963.1 - 9.5e-05 22.3 0.1 0.00024 21.0 0.0 1.6 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KZN86963.1 - 0.00025 20.5 0.0 0.014 14.8 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KZN86963.1 - 0.0024 17.6 0.0 0.0071 16.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KZN86963.1 - 0.0048 16.9 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KZN86963.1 - 0.0054 16.0 0.0 0.012 14.9 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 KZN86963.1 - 0.007 16.4 0.0 0.048 13.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KZN86963.1 - 0.0099 16.2 0.0 0.058 13.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KZN86963.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DNA_pol3_delta PF06144.13 KZN86963.1 - 0.014 15.2 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DUF815 PF05673.13 KZN86963.1 - 0.019 14.1 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF4863 PF16155.5 KZN86963.1 - 0.051 13.4 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4863) ResIII PF04851.15 KZN86963.1 - 0.068 13.2 0.0 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 KZN86963.1 - 0.075 13.6 0.0 0.23 12.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KZN86963.1 - 0.076 12.7 0.0 0.27 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KZN86963.1 - 0.11 13.0 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KZN86963.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zn_clus PF00172.18 KZN86965.1 - 2.1e-06 27.7 10.6 4.7e-06 26.6 10.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1275 PF06912.11 KZN86966.1 - 1.4e-40 139.3 11.1 1.8e-40 139.0 11.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) AzlC PF03591.14 KZN86966.1 - 2.1 8.8 10.4 1.4 9.4 3.7 2.4 2 1 0 2 2 2 0 AzlC protein Glycophorin_A PF01102.18 KZN86969.1 - 0.0081 16.4 0.1 0.013 15.7 0.1 1.3 1 0 0 1 1 1 1 Glycophorin A HCMV_UL124 PF17609.2 KZN86969.1 - 0.024 14.8 2.6 0.043 14.0 2.6 1.4 1 0 0 1 1 1 0 Family of unknown function SKG6 PF08693.10 KZN86969.1 - 0.027 13.9 2.3 0.045 13.2 2.3 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Mid2 PF04478.12 KZN86969.1 - 0.1 12.4 0.9 0.17 11.7 0.6 1.5 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor DUF4718 PF15842.5 KZN86969.1 - 0.2 11.4 0.0 0.2 11.4 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4718) DUF515 PF04415.12 KZN86969.1 - 0.93 7.8 3.8 1.4 7.2 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF3270 PF11674.8 KZN86971.1 - 0.092 12.9 0.2 0.092 12.9 0.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3270) Hydrolase_6 PF13344.6 KZN86972.1 - 4.2e-30 103.8 0.0 9.3e-30 102.7 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KZN86972.1 - 2.6e-14 53.0 0.0 2.2e-13 50.1 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KZN86972.1 - 8.5e-12 45.8 0.0 1e-09 39.0 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KZN86972.1 - 1.3e-05 25.4 0.1 0.25 11.4 0.0 2.5 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PNK3P PF08645.11 KZN86972.1 - 0.076 12.7 0.0 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Polynucleotide kinase 3 phosphatase Acid_phosphat_B PF03767.14 KZN86972.1 - 0.17 11.4 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) LAGLIDADG_3 PF14528.6 KZN86972.1 - 0.54 10.6 2.6 0.31 11.4 0.3 1.8 2 0 0 2 2 2 0 LAGLIDADG-like domain HTH_42 PF06224.12 KZN86973.1 - 0.0034 17.0 0.0 0.0043 16.6 0.0 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain NUDIX PF00293.28 KZN86976.1 - 2.7e-07 30.7 0.0 1.1e-06 28.7 0.0 2.0 1 1 1 2 2 2 1 NUDIX domain LETM1 PF07766.13 KZN86977.1 - 2.6e-101 338.5 0.1 5e-101 337.5 0.1 1.5 1 0 0 1 1 1 1 LETM1-like protein DUF2838 PF10998.8 KZN86978.1 - 1.9e-42 144.0 11.0 1.9e-42 144.0 11.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Atg14 PF10186.9 KZN86978.1 - 0.013 14.6 3.7 0.022 13.9 3.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2841 PF11001.8 KZN86979.1 - 9.2e-48 161.4 0.1 1.4e-47 160.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Glyco_hydro_62 PF03664.13 KZN86980.1 - 1.3e-160 533.0 16.9 1.6e-160 532.8 16.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Glyco_hydro_10 PF00331.20 KZN86981.1 - 7.3e-103 344.0 0.0 8.6e-103 343.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Lipase_3 PF01764.25 KZN86982.1 - 6.5e-36 123.3 0.0 9.4e-36 122.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.20 KZN86982.1 - 0.0013 18.4 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DUF2974 PF11187.8 KZN86982.1 - 0.0022 17.6 0.4 0.038 13.5 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Thioesterase PF00975.20 KZN86982.1 - 0.0026 17.9 0.1 0.0035 17.5 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 KZN86982.1 - 0.0068 15.7 0.1 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KZN86982.1 - 0.022 15.3 0.0 0.034 14.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 KZN86982.1 - 0.053 13.2 0.0 0.099 12.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase SPATA3 PF15662.5 KZN86983.1 - 9.7 6.8 10.5 16 6.1 10.5 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family SMC_N PF02463.19 KZN86984.1 - 4e-60 203.0 0.0 1e-58 198.4 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KZN86984.1 - 3.4e-30 104.8 0.1 1.4e-29 102.8 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KZN86984.1 - 1.5e-08 34.8 18.8 2.8e-05 24.1 0.0 4.6 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KZN86984.1 - 4.5e-08 32.7 0.0 1.1e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KZN86984.1 - 2.7e-07 30.6 10.6 2.7e-07 30.6 10.6 4.3 3 1 1 4 4 3 1 AAA ATPase domain AAA_23 PF13476.6 KZN86984.1 - 1.6e-05 25.5 35.2 1.6e-05 25.5 35.2 6.6 3 2 1 5 5 3 1 AAA domain SbcCD_C PF13558.6 KZN86984.1 - 0.0037 17.5 0.0 0.025 14.8 0.0 2.5 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF5082 PF16888.5 KZN86984.1 - 0.0053 17.0 11.9 0.0053 17.0 11.9 7.6 5 2 3 8 8 7 1 Domain of unknown function (DUF5082) DUF4200 PF13863.6 KZN86984.1 - 0.006 17.0 7.4 0.006 17.0 7.4 8.5 4 2 4 8 8 6 1 Domain of unknown function (DUF4200) SlyX PF04102.12 KZN86984.1 - 0.16 12.6 46.7 0.15 12.7 0.5 8.4 5 3 2 7 7 7 0 SlyX Spc7 PF08317.11 KZN86984.1 - 0.68 8.8 113.8 0.1 11.5 23.8 7.2 3 2 4 7 7 7 0 Spc7 kinetochore protein ABC_tran PF00005.27 KZN86984.1 - 0.99 9.9 0.0 0.99 9.9 0.0 6.5 4 2 1 5 5 4 0 ABC transporter CcmD PF04995.14 KZN86985.1 - 0.13 12.4 0.1 0.42 10.7 0.1 1.9 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) E3_binding PF02817.17 KZN86986.1 - 2.6e-10 40.4 0.2 2.6e-10 40.4 0.2 2.4 3 0 0 3 3 3 1 e3 binding domain WD40 PF00400.32 KZN86987.1 - 4.1e-25 87.6 12.4 3.4e-05 24.5 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN86987.1 - 6.1e-14 52.1 5.5 0.00034 20.8 0.2 4.5 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KZN86987.1 - 7.9e-09 35.7 0.1 0.0045 16.9 0.0 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KZN86987.1 - 0.038 12.9 0.0 0.11 11.4 0.0 1.8 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_M18 PF02127.15 KZN86988.1 - 4e-170 566.3 0.0 4.5e-170 566.1 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) DUF1746 PF08508.10 KZN86989.1 - 1.8e-37 128.2 2.5 2.5e-37 127.7 2.5 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) G6B PF15096.6 KZN86989.1 - 0.1 12.3 0.0 0.63 9.8 0.0 1.9 1 1 1 2 2 2 0 G6B family CLP_protease PF00574.23 KZN86990.1 - 3.7e-75 251.8 0.0 4.8e-75 251.4 0.0 1.1 1 0 0 1 1 1 1 Clp protease Peptidase_S49 PF01343.18 KZN86990.1 - 0.084 12.8 0.1 0.17 11.8 0.1 1.5 1 1 0 1 1 1 0 Peptidase family S49 DHDPS PF00701.22 KZN86990.1 - 0.097 11.4 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family Tugs PF17840.1 KZN86990.1 - 0.17 12.1 1.2 0.36 11.1 1.2 1.5 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain adh_short PF00106.25 KZN86994.1 - 1.1e-25 90.2 0.3 8.4e-20 71.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KZN86994.1 - 2.9e-11 43.4 0.1 8.1e-10 38.7 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN86994.1 - 5.3e-10 39.5 0.1 1.7e-09 37.9 0.1 1.7 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 KZN86994.1 - 5.4e-05 22.5 0.1 9.2e-05 21.7 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KZN86994.1 - 0.0088 15.5 0.1 0.018 14.5 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.13 KZN86994.1 - 0.025 14.5 0.1 4.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family ADH_zinc_N_2 PF13602.6 KZN86995.1 - 4.1e-12 47.3 0.0 9.3e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KZN86995.1 - 8.4e-10 38.7 0.0 1.7e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KZN86995.1 - 3.3e-09 36.6 0.0 6.5e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TRM PF02005.16 KZN86995.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase SLT PF01464.20 KZN86996.1 - 0.0076 15.9 0.5 0.025 14.3 0.5 1.9 1 1 0 1 1 1 1 Transglycosylase SLT domain LysM PF01476.20 KZN86996.1 - 0.023 14.7 0.0 0.099 12.7 0.0 2.0 2 0 0 2 2 2 0 LysM domain SOG2 PF10428.9 KZN86996.1 - 0.04 13.1 11.8 0.049 12.8 11.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Pex14_N PF04695.13 KZN86996.1 - 7.5 7.2 12.7 16 6.1 12.7 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AA_permease_2 PF13520.6 KZN86997.1 - 9.2e-67 225.7 42.6 1.2e-66 225.3 42.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN86997.1 - 5.2e-24 84.7 36.6 6.9e-24 84.3 36.6 1.0 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.21 KZN86997.1 - 0.1 12.5 0.0 0.1 12.5 0.0 3.6 3 0 0 3 3 3 0 LPXTG cell wall anchor motif STIMATE PF12400.8 KZN86997.1 - 3.9 8.0 11.2 2.1 8.9 7.1 2.5 2 0 0 2 2 2 0 STIMATE family ABA_GPCR PF12430.8 KZN86998.1 - 0.83 9.4 9.1 0.08 12.7 4.2 1.8 2 0 0 2 2 2 0 Abscisic acid G-protein coupled receptor Transferase PF02458.15 KZN86999.1 - 3.8e-20 72.0 0.0 1.7e-18 66.5 0.0 2.0 2 0 0 2 2 2 2 Transferase family MGDG_synth PF06925.11 KZN86999.1 - 0.046 13.8 0.0 0.086 13.0 0.0 1.3 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_hydro_38N PF01074.22 KZN87000.1 - 8.6e-89 297.7 2.0 8.6e-89 297.7 2.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KZN87000.1 - 4.7e-60 203.3 0.1 3.7e-59 200.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KZN87000.1 - 5e-27 93.9 0.0 9.9e-27 92.9 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KZN87000.1 - 2e-09 37.4 0.0 4.3e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 KZN87000.1 - 0.08 12.1 0.0 0.19 10.9 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 NuA4 PF09340.10 KZN87001.1 - 8.9e-28 96.0 0.3 8.9e-28 96.0 0.3 1.7 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Ctr PF04145.15 KZN87002.1 - 4.5e-30 105.2 1.2 5.5e-30 104.9 1.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Cupin_8 PF13621.6 KZN87003.1 - 2e-14 53.9 0.0 1.2e-12 48.1 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KZN87003.1 - 3.5e-10 40.3 0.0 3e-09 37.3 0.0 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 KZN87003.1 - 2.5e-07 30.5 0.0 5.4e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN87003.1 - 0.013 15.3 0.0 0.031 14.1 0.0 1.7 1 0 0 1 1 1 0 F-box domain DEAD PF00270.29 KZN87004.1 - 2.7e-44 151.0 0.8 5e-44 150.1 0.8 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KZN87004.1 - 1.6e-31 108.9 0.1 1.2e-30 106.1 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KZN87004.1 - 3.2e-05 24.0 0.0 5.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KZN87004.1 - 0.00021 21.1 0.1 0.0004 20.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KZN87004.1 - 0.00083 19.7 0.6 0.0048 17.2 0.4 2.1 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KZN87004.1 - 0.005 17.1 0.5 0.028 14.7 0.5 2.2 1 1 0 1 1 1 1 AAA domain IL17R_D_N PF16742.5 KZN87004.1 - 0.045 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D CMS1 PF14617.6 KZN87004.1 - 0.068 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit FAA_hydrolase PF01557.18 KZN87005.1 - 1.2e-53 182.0 0.0 1.4e-53 181.8 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family YlqD PF11068.8 KZN87005.1 - 0.087 13.2 0.1 0.12 12.8 0.1 1.4 1 1 0 1 1 1 0 YlqD protein UDPGT PF00201.18 KZN87007.1 - 2.1e-06 26.9 0.0 2.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UnbV_ASPIC PF07593.12 KZN87007.1 - 0.018 15.0 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 ASPIC and UnbV p450 PF00067.22 KZN87008.1 - 1e-58 199.2 0.0 1.3e-58 198.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DAO PF01266.24 KZN87009.1 - 7.7e-27 94.8 0.1 8.9e-27 94.6 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KZN87009.1 - 0.00017 22.1 0.7 0.00086 19.8 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KZN87009.1 - 0.0018 17.6 0.0 0.0054 16.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KZN87009.1 - 0.0021 17.4 0.6 0.0032 16.8 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KZN87009.1 - 0.0025 18.0 0.0 0.0061 16.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 KZN87009.1 - 0.0025 17.5 0.2 0.0025 17.5 0.2 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 KZN87009.1 - 0.0036 16.4 0.0 0.0057 15.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 KZN87009.1 - 0.024 14.5 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KZN87009.1 - 0.06 13.8 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding HI0933_like PF03486.14 KZN87009.1 - 0.066 11.9 0.2 0.094 11.4 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 KZN87009.1 - 0.081 12.5 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.6 KZN87009.1 - 0.1 11.8 0.0 0.26 10.5 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.12 KZN87009.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Glu_dehyd_C PF16912.5 KZN87009.1 - 0.19 11.2 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus AA_permease PF00324.21 KZN87010.1 - 2.3e-72 244.2 37.2 2.8e-72 243.8 37.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KZN87010.1 - 4.6e-19 68.6 43.1 6.1e-19 68.2 43.1 1.2 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.8 KZN87011.1 - 7.3e-33 113.9 2.4 6.8e-29 100.8 0.7 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain Vps35 PF03635.17 KZN87011.1 - 0.038 12.5 0.1 0.063 11.8 0.1 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 MBOAT_2 PF13813.6 KZN87012.1 - 1.7e-24 85.9 2.0 4.9e-24 84.4 2.0 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MFS_1 PF07690.16 KZN87013.1 - 2.3e-43 148.5 44.9 2.3e-43 148.5 44.9 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KZN87013.1 - 4.8e-18 64.9 14.9 4.8e-18 64.9 14.9 2.4 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KZN87013.1 - 5.9e-11 41.9 13.4 5.9e-11 41.9 13.4 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter CbtB PF09489.10 KZN87013.1 - 7.3 6.8 7.5 8.9 6.5 0.1 3.8 4 0 0 4 4 4 0 Probable cobalt transporter subunit (CbtB) MFS_1 PF07690.16 KZN87014.1 - 4.1e-20 72.0 38.8 1.1e-19 70.5 27.6 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN87014.1 - 1.9e-14 53.4 17.1 5.2e-14 52.0 17.1 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter Tmemb_170 PF10190.9 KZN87014.1 - 0.011 16.1 1.7 0.011 16.1 1.7 3.6 3 1 1 4 4 4 0 Putative transmembrane protein 170 PhyH PF05721.13 KZN87015.1 - 5.6e-07 30.0 0.1 1.3e-06 28.8 0.1 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KZN87015.1 - 5.4e-05 22.1 0.2 0.19 10.4 0.0 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_3 PF13640.6 KZN87015.1 - 0.14 13.0 0.0 0.39 11.6 0.0 1.7 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Peptidase_S15 PF02129.18 KZN87016.1 - 1.7e-41 142.6 0.9 1.4e-39 136.4 0.1 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KZN87016.1 - 7.9e-32 111.0 0.0 1.1e-31 110.6 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 KZN87016.1 - 0.016 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 AXE1 PF05448.12 KZN87016.1 - 0.11 11.2 0.1 8.5 4.9 0.1 2.3 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) Fungal_trans PF04082.18 KZN87017.1 - 6e-15 55.0 0.1 1.7e-14 53.5 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN87017.1 - 6e-09 35.9 14.0 1.1e-08 35.1 14.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhyH PF05721.13 KZN87018.1 - 1.2e-06 28.9 0.2 3e-06 27.6 0.2 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KZN87018.1 - 3.4e-05 22.8 0.0 0.18 10.6 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_3 PF13640.6 KZN87018.1 - 0.094 13.6 0.0 0.21 12.5 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 KZN87019.1 - 1.1e-06 27.9 0.2 1.6e-06 27.3 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PWI PF01480.17 KZN87021.1 - 1.3e-29 102.3 0.1 2e-29 101.7 0.1 1.3 1 0 0 1 1 1 1 PWI domain Pkinase PF00069.25 KZN87022.1 - 1.3e-46 159.1 0.0 1.9e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN87022.1 - 8.8e-17 61.2 0.0 1.3e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KZN87022.1 - 0.0027 17.3 0.2 0.0053 16.4 0.2 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KZN87022.1 - 0.015 15.2 0.1 0.42 10.5 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KZN87022.1 - 0.024 13.9 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KZN87022.1 - 0.046 13.1 0.1 0.076 12.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KZN87022.1 - 0.056 12.2 2.2 0.059 12.1 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase Pns11_12 PF17464.2 KZN87022.1 - 0.097 12.4 2.9 0.32 10.7 2.9 1.8 1 0 0 1 1 1 0 Non-structural protein 11 and 12 DUF5094 PF17015.5 KZN87022.1 - 0.15 12.1 0.2 0.88 9.7 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5094) PsaA_PsaB PF00223.19 KZN87022.1 - 0.32 9.1 0.0 0.46 8.6 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein Ribosomal_S8e PF01201.22 KZN87023.1 - 2.4e-41 141.1 1.0 2.6e-41 141.0 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Ribosomal_L21p PF00829.21 KZN87024.1 - 6.6e-09 35.9 0.0 9.6e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Fungal_trans PF04082.18 KZN87025.1 - 3.6e-19 68.8 0.2 6.6e-19 68.0 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN87025.1 - 0.0015 18.6 6.7 0.0034 17.5 6.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_Rpb4 PF03874.16 KZN87026.1 - 6e-26 91.2 2.1 7.9e-26 90.8 2.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Cut8 PF08559.10 KZN87026.1 - 0.0025 17.5 0.6 0.003 17.2 0.6 1.2 1 1 0 1 1 1 1 Cut8, nuclear proteasome tether protein Met_10 PF02475.16 KZN87027.1 - 7.6e-66 221.6 0.0 1.1e-65 221.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein zf-GRF PF06839.12 KZN87028.1 - 9.5e-08 32.0 5.0 1.8e-07 31.1 5.0 1.5 1 0 0 1 1 1 1 GRF zinc finger Ank_2 PF12796.7 KZN87029.1 - 6.4e-54 180.5 0.0 1.2e-15 57.8 0.0 5.9 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.30 KZN87029.1 - 3.5e-44 147.4 1.0 0.00013 22.2 0.0 10.3 8 1 1 9 9 9 8 Ankyrin repeat Ank_4 PF13637.6 KZN87029.1 - 3.3e-42 142.3 0.0 1.3e-09 38.4 0.0 7.2 5 2 2 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KZN87029.1 - 4.1e-36 122.6 4.7 7.9e-10 38.8 0.1 8.8 2 2 7 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN87029.1 - 4.3e-35 115.8 0.1 0.0034 17.7 0.0 10.2 10 0 0 10 10 10 8 Ankyrin repeat DUF3818 PF12825.7 KZN87030.1 - 4e-97 325.3 4.0 6.5e-97 324.6 4.0 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) Vps5 PF09325.10 KZN87030.1 - 0.0034 17.0 0.4 0.0071 15.9 0.4 1.4 1 0 0 1 1 1 1 Vps5 C terminal like DUF4050 PF13259.6 KZN87030.1 - 0.13 12.6 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) DUF2373 PF10180.9 KZN87030.1 - 0.2 11.5 1.6 0.46 10.4 1.6 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) PXB PF12828.7 KZN87031.1 - 1.5e-37 128.5 0.2 2.5e-37 127.8 0.2 1.4 1 0 0 1 1 1 1 PX-associated DUF3818 PF12825.7 KZN87031.1 - 7.4e-16 58.1 0.0 1.4e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PX PF00787.24 KZN87031.1 - 1.7e-14 53.8 2.3 3.5e-14 52.8 0.1 2.6 3 1 0 3 3 3 1 PX domain zf-C2H2 PF00096.26 KZN87032.1 - 0.00014 22.1 2.5 0.00014 22.1 2.5 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KZN87032.1 - 0.85 10.2 19.7 3.8 8.1 3.2 3.7 3 0 0 3 3 3 0 Zinc-finger double domain NAD_Gly3P_dh_N PF01210.23 KZN87034.1 - 1.2e-47 161.8 0.0 2.1e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KZN87034.1 - 5.1e-36 124.1 0.0 7.9e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus GerE PF00196.19 KZN87034.1 - 0.12 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family F420_oxidored PF03807.17 KZN87034.1 - 0.13 12.9 0.0 17 6.1 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Catalase PF00199.19 KZN87035.1 - 4.9e-176 585.5 0.5 6.6e-176 585.1 0.5 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KZN87035.1 - 1.3e-17 63.8 0.1 2.7e-17 62.7 0.1 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 KZN87035.1 - 1.3e-07 31.3 0.1 2.9e-07 30.2 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 KZN87035.1 - 0.0044 16.8 0.0 0.0072 16.1 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Fungal_trans_2 PF11951.8 KZN87036.1 - 6.9e-29 100.8 2.0 8.5e-29 100.5 2.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain HD PF01966.22 KZN87037.1 - 0.00013 22.1 0.0 0.00024 21.3 0.0 1.6 1 1 0 1 1 1 1 HD domain adh_short PF00106.25 KZN87038.1 - 5.2e-45 153.3 0.3 7.4e-45 152.8 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN87038.1 - 2.2e-43 148.5 0.1 3.7e-43 147.8 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN87038.1 - 2.1e-10 40.8 1.8 1.7e-09 37.9 1.8 2.0 1 1 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 KZN87038.1 - 0.00069 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KZN87038.1 - 0.00097 18.7 0.2 0.0047 16.4 0.0 2.0 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus DUF1776 PF08643.10 KZN87038.1 - 0.0064 15.9 1.7 0.014 14.8 1.7 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Shikimate_DH PF01488.20 KZN87038.1 - 0.0065 16.5 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 KZN87038.1 - 0.012 15.0 0.4 0.054 12.9 0.1 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KZN87038.1 - 0.013 15.0 0.1 0.025 14.1 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family E7R PF17467.2 KZN87038.1 - 0.17 12.0 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 Viral Protein E7 adh_short_C2 PF13561.6 KZN87039.1 - 2.6e-44 151.5 0.3 3.4e-44 151.2 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN87039.1 - 1.4e-38 132.3 0.2 1.8e-38 131.9 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN87039.1 - 4.6e-10 39.7 1.3 8.6e-10 38.8 1.3 1.4 1 1 0 1 1 1 1 KR domain HATPase_c PF02518.26 KZN87039.1 - 0.034 14.7 0.0 0.073 13.6 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA PF00004.29 KZN87041.1 - 1e-47 161.9 0.0 5.4e-43 146.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KZN87041.1 - 1.4e-06 28.0 7.5 9.5e-05 22.1 0.1 3.2 3 0 0 3 3 2 2 AAA+ lid domain AAA_16 PF13191.6 KZN87041.1 - 8.2e-05 23.1 0.0 0.022 15.2 0.0 3.3 2 0 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KZN87041.1 - 0.00016 21.4 0.0 0.00043 20.1 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 KZN87041.1 - 0.00057 19.1 0.0 0.00097 18.3 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_22 PF13401.6 KZN87041.1 - 0.002 18.4 0.0 0.046 14.0 0.0 3.2 3 1 1 4 4 4 1 AAA domain AAA_2 PF07724.14 KZN87041.1 - 0.0038 17.3 0.0 0.0098 16.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 KZN87041.1 - 0.0043 17.4 0.0 0.015 15.7 0.0 2.0 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 KZN87041.1 - 0.007 15.6 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_25 PF13481.6 KZN87041.1 - 0.0075 15.9 0.2 0.041 13.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KZN87041.1 - 0.0097 15.7 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 KZN87041.1 - 0.015 14.8 0.0 0.041 13.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KZN87041.1 - 0.027 13.9 0.1 0.055 12.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KZN87041.1 - 0.036 14.6 0.1 0.11 13.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain ATPase PF06745.13 KZN87041.1 - 0.039 13.3 0.0 0.083 12.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.14 KZN87041.1 - 0.041 13.9 0.0 0.13 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KZN87041.1 - 0.064 13.4 0.1 0.45 10.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 KZN87041.1 - 0.064 13.3 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KZN87041.1 - 0.095 12.9 0.0 0.31 11.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain PhoH PF02562.16 KZN87041.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Vps4_C PF09336.10 KZN87041.1 - 0.17 11.9 0.1 1.5 8.9 0.0 2.4 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain CEP1-DNA_bind PF09287.10 KZN87042.1 - 0.11 12.1 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 CEP-1, DNA binding KGG PF10685.9 KZN87043.1 - 4.5e-24 84.0 20.5 1.3e-09 38.0 0.7 3.1 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif CHZ PF09649.10 KZN87044.1 - 0.013 15.0 0.3 0.032 13.7 0.3 1.6 1 0 0 1 1 1 0 Histone chaperone domain CHZ Na_trans_assoc PF06512.13 KZN87044.1 - 0.1 12.9 2.8 0.1 12.9 2.8 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Glyco_transf_20 PF00982.21 KZN87045.1 - 1.3e-145 485.7 0.0 1.9e-145 485.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KZN87045.1 - 1.8e-36 125.4 0.0 2.8e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase CAS_CSE1 PF03378.15 KZN87045.1 - 0.1 11.1 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus MADF_DNA_bdg PF10545.9 KZN87045.1 - 2.4 8.5 5.2 6.2 7.2 2.9 2.6 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like AA_permease_2 PF13520.6 KZN87046.1 - 6.8e-56 189.9 52.4 8.5e-56 189.6 52.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN87046.1 - 2.1e-14 53.0 43.1 3.1e-14 52.4 43.1 1.1 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.21 KZN87046.1 - 0.062 13.3 0.1 0.57 10.2 0.0 2.8 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Questin_oxidase PF14027.6 KZN87047.1 - 5.4e-74 249.8 0.0 6.4e-74 249.5 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like Imm51 PF15595.6 KZN87047.1 - 0.11 12.5 0.1 9.4 6.2 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 51 HECT_2 PF09814.9 KZN87048.1 - 2.1e-111 372.4 0.1 2.4e-111 372.2 0.1 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding TauD PF02668.16 KZN87049.1 - 3.5e-58 197.5 0.7 4.3e-58 197.2 0.7 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 KZN87050.1 - 5.3e-25 88.1 19.6 8.5e-25 87.4 19.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4500 PF14937.6 KZN87050.1 - 0.0045 17.0 0.3 0.012 15.7 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4500) DUF3446 PF11928.8 KZN87050.1 - 0.027 14.8 1.2 0.19 12.0 1.3 2.1 2 0 0 2 2 2 0 Early growth response N-terminal domain PI-PLC-X PF00388.19 KZN87052.1 - 2.5e-52 176.3 2.1 1.4e-51 173.9 2.1 2.2 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KZN87052.1 - 6.1e-39 132.9 2.2 6.4e-39 132.9 0.1 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain eIF3_subunit PF08597.10 KZN87052.1 - 0.0057 16.6 2.4 0.012 15.5 2.4 1.4 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit AF-4 PF05110.13 KZN87052.1 - 0.013 13.6 5.5 0.019 13.1 5.5 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein GST_N_3 PF13417.6 KZN87053.1 - 1.8e-08 34.6 0.1 5.2e-08 33.2 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KZN87053.1 - 4.9e-05 23.5 0.0 9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KZN87053.1 - 0.0023 17.9 0.0 0.0036 17.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KZN87053.1 - 0.17 12.1 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ribosomal_L37 PF08561.10 KZN87054.1 - 1.7e-41 141.5 0.6 2.2e-41 141.1 0.6 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 GDP_Man_Dehyd PF16363.5 KZN87055.1 - 4.6e-37 128.2 0.0 2.1e-36 126.0 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KZN87055.1 - 3.6e-36 124.9 0.0 3.2e-35 121.7 0.0 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KZN87055.1 - 1.9e-08 33.8 0.0 1.5e-06 27.6 0.0 2.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KZN87055.1 - 5e-07 29.2 0.0 8.5e-06 25.1 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KZN87055.1 - 3.4e-06 26.3 0.0 2.2e-05 23.6 0.0 2.3 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KZN87055.1 - 0.0021 17.2 0.0 0.011 14.9 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain Pyr_redox_2 PF07992.14 KZN87055.1 - 0.0024 17.2 0.0 0.0038 16.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase KR PF08659.10 KZN87055.1 - 0.003 17.5 0.0 0.0059 16.5 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KZN87055.1 - 0.004 16.6 0.0 0.016 14.7 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Spherulin4 PF12138.8 KZN87056.1 - 1.5e-75 254.0 0.2 1.7e-75 253.7 0.2 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Ferrochelatase PF00762.19 KZN87056.1 - 0.051 12.6 0.0 0.072 12.2 0.0 1.1 1 0 0 1 1 1 0 Ferrochelatase Glyco_hydro_114 PF03537.13 KZN87057.1 - 4e-83 278.3 2.9 4.9e-83 278.0 2.9 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Glyco_trans_1_4 PF13692.6 KZN87059.1 - 2.5e-11 44.1 0.0 6.6e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KZN87059.1 - 3e-11 43.2 0.0 6.4e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.8 KZN87059.1 - 0.0079 16.0 0.1 0.023 14.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3492) DPPIV_N PF00930.21 KZN87060.1 - 7.9e-114 380.1 0.2 1.3e-113 379.4 0.0 1.4 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KZN87060.1 - 2.8e-53 180.6 1.5 4.9e-53 179.8 1.5 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KZN87060.1 - 4e-05 23.4 2.0 0.00012 21.8 1.3 2.0 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 KZN87060.1 - 0.0032 17.2 0.2 0.0066 16.1 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 KZN87060.1 - 0.0035 15.9 0.0 1.7 7.0 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II AXE1 PF05448.12 KZN87060.1 - 0.0082 14.8 0.0 0.024 13.3 0.0 1.7 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Esterase PF00756.20 KZN87060.1 - 0.011 15.5 0.1 0.033 13.8 0.1 1.6 1 1 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 KZN87060.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cpn60_TCP1 PF00118.24 KZN87061.1 - 4.5e-148 493.9 11.6 5e-148 493.8 11.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA PF00004.29 KZN87062.1 - 1.5e-40 138.7 0.0 2.6e-40 137.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KZN87062.1 - 8.6e-06 25.5 0.1 2e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KZN87062.1 - 9e-05 22.8 0.0 0.0059 16.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KZN87062.1 - 0.00013 22.0 0.1 0.00062 19.8 0.0 2.1 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KZN87062.1 - 0.00037 20.9 0.1 0.0075 16.7 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 KZN87062.1 - 0.00041 20.5 0.0 0.0013 18.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KZN87062.1 - 0.0018 17.5 0.0 0.0031 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KZN87062.1 - 0.0094 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KZN87062.1 - 0.027 14.0 0.0 0.088 12.3 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 KZN87062.1 - 0.03 14.6 0.0 0.063 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KZN87062.1 - 0.051 13.7 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KZN87062.1 - 0.063 13.7 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 KZN87062.1 - 0.088 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KZN87062.1 - 0.095 12.4 0.1 0.59 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KZN87062.1 - 0.1 12.3 0.1 0.24 11.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KZN87062.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain FAD_binding_2 PF00890.24 KZN87063.1 - 6.1e-125 417.6 3.8 7.6e-125 417.3 3.8 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KZN87063.1 - 1.4e-44 151.2 0.7 2.1e-44 150.6 0.7 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 KZN87063.1 - 4.5e-07 29.4 1.5 0.00097 18.4 0.6 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KZN87063.1 - 3.4e-05 23.1 0.7 0.019 14.1 1.2 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 KZN87063.1 - 4.5e-05 22.8 0.2 0.038 13.2 0.0 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 KZN87063.1 - 0.0012 18.2 0.1 0.0025 17.1 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KZN87063.1 - 0.033 13.8 1.7 0.1 12.1 1.7 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase PAPS_reduct PF01507.19 KZN87063.1 - 0.16 12.0 0.1 0.29 11.2 0.1 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family HI0933_like PF03486.14 KZN87063.1 - 0.28 9.8 1.5 1.1 7.8 0.5 2.4 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox_3 PF13738.6 KZN87063.1 - 1.9 7.6 3.2 5.5 6.2 0.7 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Adeno_E3_CR2 PF02439.15 KZN87064.1 - 8.1e-05 22.3 6.6 0.00016 21.4 6.6 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Mid2 PF04478.12 KZN87064.1 - 0.0021 17.9 0.2 0.0021 17.9 0.2 2.6 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor EphA2_TM PF14575.6 KZN87064.1 - 0.004 18.0 0.0 0.0091 16.9 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Beta-APP PF03494.13 KZN87064.1 - 0.0048 16.7 4.2 0.0092 15.8 4.2 1.4 1 0 0 1 1 1 1 Beta-amyloid peptide (beta-APP) Herpes_gE PF02480.16 KZN87064.1 - 0.019 13.7 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SKG6 PF08693.10 KZN87064.1 - 0.11 11.9 1.5 0.25 10.8 1.5 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.20 KZN87064.1 - 0.17 11.8 0.3 0.29 11.1 0.3 1.3 1 0 0 1 1 1 0 Syndecan domain DUF2207 PF09972.9 KZN87064.1 - 0.26 10.0 0.0 0.37 9.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM154 PF15102.6 KZN87064.1 - 0.47 10.3 0.0 0.47 10.3 0.0 2.4 1 1 1 2 2 2 0 TMEM154 protein family Lyase_1 PF00206.20 KZN87065.1 - 5.7e-84 282.2 0.0 9.9e-84 281.4 0.0 1.4 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KZN87065.1 - 1.4e-23 83.4 0.1 5.1e-23 81.6 0.1 2.0 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal FR47 PF08445.10 KZN87066.1 - 6.3e-07 29.3 0.0 0.0025 17.7 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_3 PF13302.7 KZN87066.1 - 0.047 14.4 0.0 0.095 13.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KZN87066.1 - 0.16 12.2 0.0 0.43 10.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Fungal_trans PF04082.18 KZN87069.1 - 2.5e-11 43.1 0.4 5.1e-11 42.1 0.4 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KZN87069.1 - 2.1e-05 24.7 7.6 4e-05 23.8 1.7 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KZN87069.1 - 5.9e-05 23.3 18.7 0.0005 20.4 4.0 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type Zn_clus PF00172.18 KZN87069.1 - 6.2e-05 23.0 10.7 6.2e-05 23.0 10.7 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 KZN87069.1 - 0.022 15.6 3.1 0.022 15.6 3.1 4.6 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KZN87069.1 - 0.077 13.3 4.6 4.6 7.7 1.4 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KZN87069.1 - 0.37 11.3 4.5 1.1 9.7 0.7 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type p450 PF00067.22 KZN87071.1 - 8.7e-72 242.3 0.0 1.1e-71 242.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Copper-fist PF00649.18 KZN87072.1 - 0.26 10.8 2.2 0.22 11.0 0.5 1.8 2 0 0 2 2 2 0 Copper fist DNA binding domain SH3_9 PF14604.6 KZN87073.1 - 1.7e-24 85.4 0.4 4.3e-12 45.7 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 KZN87073.1 - 1.6e-22 79.5 0.0 4.3e-22 78.2 0.0 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KZN87073.1 - 5.3e-19 67.6 1.1 7e-10 38.4 0.0 2.7 3 0 0 3 3 3 2 SH3 domain C1_1 PF00130.22 KZN87073.1 - 4.5e-15 55.3 5.6 4.5e-15 55.3 5.6 1.6 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_10 PF17902.1 KZN87073.1 - 0.00061 19.8 0.0 0.97 9.5 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KZN87073.1 - 0.00075 19.1 0.0 0.27 11.0 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain Cortex-I_coil PF09304.10 KZN87073.1 - 0.0053 17.0 3.2 3.2 8.0 0.0 3.4 3 1 0 3 3 3 2 Cortexillin I, coiled coil C1_2 PF03107.16 KZN87073.1 - 0.0057 16.9 4.2 0.011 16.1 4.2 1.4 1 0 0 1 1 1 1 C1 domain SH3_3 PF08239.11 KZN87073.1 - 0.074 13.4 0.1 1 9.7 0.0 2.4 2 0 0 2 2 2 0 Bacterial SH3 domain FYVE PF01363.21 KZN87073.1 - 0.18 12.0 3.4 0.42 10.8 3.4 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-RING_9 PF13901.6 KZN87073.1 - 5 7.0 7.7 7.9 6.4 5.0 2.2 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon DEAD PF00270.29 KZN87074.1 - 8e-33 113.7 0.0 1.7e-32 112.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KZN87074.1 - 7.5e-24 84.2 0.0 1.9e-23 82.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain IMPa_N_2 PF18650.1 KZN87074.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain Fungal_trans PF04082.18 KZN87075.1 - 7.5e-09 35.0 0.7 2.4e-08 33.4 0.1 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN87075.1 - 1.5e-06 28.2 7.2 3e-06 27.3 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GTP_CH_N PF12471.8 KZN87076.1 - 7.3e-88 293.4 0.0 1e-87 292.9 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 KZN87076.1 - 1.4e-17 63.7 0.0 2.1e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II GntR PF00392.21 KZN87076.1 - 0.18 11.5 0.0 6.3 6.5 0.0 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, gntR family DUF2014 PF09427.10 KZN87077.1 - 2.6e-98 328.6 0.1 3.7e-98 328.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 KZN87077.1 - 4e-18 65.1 0.5 9.4e-18 63.9 0.5 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain NAD_binding_6 PF08030.12 KZN87078.1 - 3.4e-19 69.5 0.0 1.8e-18 67.2 0.0 2.2 2 1 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KZN87078.1 - 7.8e-18 64.8 10.4 7.8e-18 64.8 10.4 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KZN87078.1 - 9.4e-11 41.8 0.0 8.7e-08 32.2 0.0 2.8 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 KZN87078.1 - 0.022 15.4 0.1 1.1 10.0 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF3632 PF12311.8 KZN87079.1 - 1.5e-28 100.4 0.4 2.8e-28 99.5 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) FSH1 PF03959.13 KZN87080.1 - 1.4e-30 106.6 0.0 2.5e-30 105.7 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) ADH_zinc_N PF00107.26 KZN87081.1 - 5e-12 45.9 0.0 1.3e-11 44.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KZN87081.1 - 5.9e-06 26.1 0.1 0.00016 21.6 0.0 2.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KZN87081.1 - 0.00059 20.9 0.0 0.002 19.2 0.0 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase E1-E2_ATPase PF00122.20 KZN87082.1 - 1.1e-42 145.6 7.3 8.3e-32 110.2 0.0 3.4 2 1 1 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KZN87082.1 - 1.5e-27 96.5 2.7 1.5e-27 96.5 2.7 2.4 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KZN87082.1 - 1.1e-17 65.0 0.0 5.3e-17 62.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KZN87082.1 - 7.2e-14 51.2 0.0 2.2e-13 49.7 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KZN87082.1 - 1.6e-12 47.3 0.0 3.2e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KZN87082.1 - 6.3e-07 29.4 2.4 1e-05 25.5 1.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 KZN87082.1 - 0.0043 17.0 1.4 0.014 15.3 1.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) NAD_kinase PF01513.21 KZN87084.1 - 5e-79 265.5 0.0 6.7e-79 265.1 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase NmrA PF05368.13 KZN87086.1 - 1.7e-22 80.2 0.0 2.9e-15 56.5 0.0 2.0 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 KZN87086.1 - 3.2e-08 33.7 0.1 7.2e-08 32.5 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding GAF_2 PF13185.6 KZN87087.1 - 1.5e-12 48.0 0.0 2.4e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KZN87087.1 - 7.4e-09 36.3 0.0 1e-08 35.9 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 KZN87087.1 - 0.00032 21.1 0.0 0.00058 20.2 0.0 1.4 1 0 0 1 1 1 1 GAF domain adh_short PF00106.25 KZN87088.1 - 3.6e-53 179.9 0.4 4.5e-53 179.6 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN87088.1 - 1.1e-51 175.7 0.9 1.3e-51 175.4 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN87088.1 - 1.2e-10 41.6 0.1 1.6e-10 41.2 0.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KZN87088.1 - 4.2e-05 23.5 0.0 7.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 KZN87088.1 - 0.00015 21.3 0.1 0.00036 20.1 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KZN87088.1 - 0.00018 20.8 0.1 0.00026 20.2 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 KZN87088.1 - 0.00037 21.1 0.0 0.00081 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.19 KZN87088.1 - 0.00041 19.4 0.1 0.00057 19.0 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 KZN87088.1 - 0.00081 19.9 0.0 0.0015 19.0 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KZN87088.1 - 0.0033 17.7 0.1 0.0065 16.7 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 KZN87088.1 - 0.0056 15.8 0.0 0.0081 15.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KZN87088.1 - 0.0084 15.5 0.1 0.012 15.0 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 KZN87088.1 - 0.0088 16.3 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.6 KZN87088.1 - 0.016 15.6 0.0 0.029 14.8 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding DFP PF04127.15 KZN87088.1 - 0.043 13.6 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein ApbA PF02558.16 KZN87088.1 - 0.045 13.4 0.0 0.097 12.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA THF_DHG_CYH_C PF02882.19 KZN87088.1 - 0.059 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Methyltransf_12 PF08242.12 KZN87088.1 - 0.062 14.1 0.0 0.11 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_10 PF13460.6 KZN87088.1 - 0.063 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding AdoHcyase_NAD PF00670.21 KZN87088.1 - 0.091 12.8 3.2 0.39 10.8 3.0 2.0 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_3 PF03447.16 KZN87088.1 - 0.11 13.2 0.1 0.22 12.2 0.1 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Sod_Cu PF00080.20 KZN87089.1 - 8e-39 133.0 2.0 8.8e-39 132.9 2.0 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Cas_CXXC_CXXC PF09706.10 KZN87090.1 - 0.082 13.2 0.4 0.22 11.8 0.0 1.9 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) adh_short PF00106.25 KZN87091.1 - 1.2e-25 90.1 0.0 1.7e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN87091.1 - 6.1e-25 88.1 0.0 8.8e-25 87.6 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN87091.1 - 6.8e-08 32.6 0.0 9.8e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KZN87091.1 - 4.9e-05 22.9 0.0 7.2e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GFA PF04828.14 KZN87092.1 - 1.1e-13 51.3 1.6 2.4e-13 50.2 1.6 1.6 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme SelR PF01641.18 KZN87092.1 - 0.1 12.7 0.1 0.25 11.4 0.1 1.5 1 1 0 1 1 1 0 SelR domain NOB1_Zn_bind PF08772.11 KZN87092.1 - 0.12 12.5 5.0 0.81 9.9 5.0 2.1 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like DUF2861 PF11060.8 KZN87093.1 - 0.15 11.6 0.1 0.26 10.8 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2861) Metallophos PF00149.28 KZN87094.1 - 8.9e-10 39.4 5.7 1.9e-09 38.4 5.7 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MARVEL PF01284.23 KZN87095.1 - 5.7e-30 104.2 8.5 6.7e-30 104.0 8.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain Clat_adaptor_s PF01217.20 KZN87096.1 - 3.9e-53 179.2 1.6 4.6e-53 179.0 1.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Fungal_trans_2 PF11951.8 KZN87096.1 - 0.034 13.0 0.0 0.044 12.6 0.0 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain Maf1 PF09174.10 KZN87097.1 - 2.3e-60 203.7 0.0 3e-60 203.4 0.0 1.1 1 0 0 1 1 1 1 Maf1 regulator Filament PF00038.21 KZN87098.1 - 4.8e-07 29.7 19.2 4.8e-07 29.7 19.2 4.2 3 2 2 5 5 5 2 Intermediate filament protein ATG16 PF08614.11 KZN87098.1 - 0.0029 17.9 19.0 0.0029 17.9 19.0 5.7 2 2 3 5 5 5 2 Autophagy protein 16 (ATG16) DUF5082 PF16888.5 KZN87098.1 - 0.0086 16.4 4.0 0.0086 16.4 4.0 6.5 3 2 3 6 6 6 2 Domain of unknown function (DUF5082) APG17 PF04108.12 KZN87098.1 - 2 7.4 32.3 1.5 7.9 17.5 2.6 1 1 1 2 2 2 0 Autophagy protein Apg17 COPIIcoated_ERV PF07970.12 KZN87099.1 - 3.9e-36 125.0 0.0 6.6e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KZN87099.1 - 8.8e-25 86.9 0.0 1.6e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pkinase PF00069.25 KZN87100.1 - 9.7e-55 185.8 0.0 1.3e-54 185.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN87100.1 - 1.5e-19 70.3 0.0 3.1e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KZN87100.1 - 0.16 11.9 0.0 0.55 10.1 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family KH_8 PF17903.1 KZN87100.1 - 0.22 11.7 0.0 0.47 10.6 0.0 1.5 1 0 0 1 1 1 0 Krr1 KH1 domain Pex24p PF06398.11 KZN87101.1 - 3.2e-90 302.8 0.0 4.4e-90 302.3 0.0 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF639 PF04842.12 KZN87101.1 - 0.062 12.7 0.6 0.11 11.8 0.6 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) Nop16 PF09420.10 KZN87102.1 - 1.1e-65 221.6 10.4 1.2e-65 221.4 10.4 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Zip PF02535.22 KZN87103.1 - 1.1e-59 202.4 6.1 2e-59 201.5 6.1 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter Phage_holin_Dp1 PF16938.5 KZN87103.1 - 0.18 12.1 1.2 0.42 10.9 0.5 2.0 2 0 0 2 2 2 0 Putative phage holin Dp-1 Anp1 PF03452.14 KZN87104.1 - 2.2e-106 355.1 0.0 2.6e-106 354.9 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 KZN87104.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Mito_carr PF00153.27 KZN87105.1 - 1.5e-44 149.8 1.7 4.4e-18 65.0 0.2 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein CCDC14 PF15254.6 KZN87106.1 - 1.1 7.8 4.3 1.6 7.3 4.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 tRNA-synt_1b PF00579.25 KZN87107.1 - 3.8e-17 62.5 0.1 1.6e-16 60.5 0.1 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Aminotran_4 PF01063.19 KZN87108.1 - 2.7e-37 128.8 0.0 3.3e-37 128.5 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV Cys_box PF17869.1 KZN87108.1 - 0.17 12.0 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Anosmin cysteine rich domain TPR_1 PF00515.28 KZN87109.1 - 3.8e-37 124.6 20.4 0.0013 18.5 0.1 11.3 10 1 1 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.17 KZN87109.1 - 3.1e-34 114.3 22.7 7.1e-05 22.6 0.1 11.1 10 1 1 11 11 11 7 Tetratricopeptide repeat TPR_16 PF13432.6 KZN87109.1 - 3e-22 79.0 13.1 1e-05 26.1 0.0 6.9 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 KZN87109.1 - 9.6e-19 66.8 20.1 0.00011 21.8 0.0 8.7 6 1 2 8 8 8 6 TPR repeat TPR_8 PF13181.6 KZN87109.1 - 1.3e-18 65.6 15.9 0.0098 16.0 0.1 9.6 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 KZN87109.1 - 9.7e-16 56.9 5.2 0.28 11.6 0.0 8.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 KZN87109.1 - 3.7e-15 55.8 6.2 3e-05 24.1 0.1 5.1 3 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KZN87109.1 - 5.7e-12 45.8 31.2 0.00071 19.8 2.2 8.7 4 3 5 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 KZN87109.1 - 1.1e-10 41.4 10.5 0.023 15.5 0.0 7.2 5 2 2 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KZN87109.1 - 3.1e-10 40.4 21.3 5.7e-05 23.6 0.8 6.9 6 2 3 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 KZN87109.1 - 3.1e-10 39.3 14.6 0.025 14.6 0.1 8.4 7 1 1 8 8 8 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 KZN87109.1 - 2.9e-06 26.6 5.1 0.12 11.8 0.0 6.0 5 0 0 5 5 5 1 SHNi-TPR TPR_MalT PF17874.1 KZN87109.1 - 9.2e-06 25.2 3.0 1.9e-05 24.2 1.8 2.1 1 1 0 1 1 1 1 MalT-like TPR region ANAPC3 PF12895.7 KZN87109.1 - 0.00015 21.9 16.5 0.13 12.5 0.0 5.1 4 1 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 MAS20 PF02064.15 KZN87109.1 - 0.0038 17.3 13.4 0.052 13.6 0.7 4.6 4 2 1 5 5 5 1 MAS20 protein import receptor TPR_6 PF13174.6 KZN87109.1 - 0.0057 17.2 20.7 6.6 7.6 0.0 8.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 KZN87109.1 - 0.012 15.5 25.5 0.23 11.4 0.4 8.1 11 0 0 11 11 8 0 Tetratricopeptide repeat HemY_N PF07219.13 KZN87109.1 - 0.018 15.2 8.1 5.5 7.2 0.0 4.4 3 1 1 4 4 4 0 HemY protein N-terminus Sel1 PF08238.12 KZN87109.1 - 0.032 14.9 3.4 0.89 10.3 0.2 4.1 3 0 0 3 3 3 0 Sel1 repeat ANAPC5 PF12862.7 KZN87109.1 - 0.22 11.6 9.4 15 5.8 0.1 4.2 3 2 1 4 4 3 0 Anaphase-promoting complex subunit 5 SPO22 PF08631.10 KZN87109.1 - 0.63 9.5 6.6 2.1 7.8 0.0 3.8 3 1 1 4 4 4 0 Meiosis protein SPO22/ZIP4 like MIT PF04212.18 KZN87109.1 - 1.8 8.7 17.9 9.7 6.3 0.1 6.6 7 1 0 7 7 6 0 MIT (microtubule interacting and transport) domain OAD_gamma PF04277.13 KZN87109.1 - 5.5 7.7 6.9 1.5 9.5 2.7 2.4 2 1 0 2 2 1 0 Oxaloacetate decarboxylase, gamma chain FHA PF00498.26 KZN87110.1 - 7.9e-12 45.4 0.0 1.5e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-C2H2 PF00096.26 KZN87112.1 - 0.046 14.2 8.6 0.76 10.4 0.3 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KZN87112.1 - 0.093 13.6 9.3 0.47 11.4 3.1 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 KZN87112.1 - 0.14 12.6 0.6 0.14 12.6 0.6 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type TFIIA PF03153.13 KZN87112.1 - 0.91 9.5 2.7 1 9.3 2.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Zip PF02535.22 KZN87114.1 - 1.6e-54 185.4 12.7 5.6e-54 183.6 12.7 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter PALP PF00291.25 KZN87115.1 - 1.4e-27 96.9 0.0 3.5e-27 95.6 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3500 PF12006.8 KZN87116.1 - 2e-111 372.3 0.0 2.4e-111 372.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) L_HMGIC_fpl PF10242.9 KZN87117.1 - 9.7e-06 25.9 4.5 1.7e-05 25.1 4.5 1.4 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein ABC2_membrane PF01061.24 KZN87117.1 - 0.0066 15.9 2.8 0.035 13.5 0.7 2.0 2 0 0 2 2 2 1 ABC-2 type transporter DUF2232 PF09991.9 KZN87117.1 - 0.72 9.0 10.5 1.2 8.3 0.5 2.7 2 1 1 3 3 3 0 Predicted membrane protein (DUF2232) RRM_1 PF00076.22 KZN87118.1 - 4.9e-54 180.0 0.1 7.9e-19 67.3 0.0 4.8 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KZN87118.1 - 4.8e-32 109.6 0.0 2.1e-27 94.8 0.0 4.3 4 1 0 4 4 4 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KZN87118.1 - 4e-09 36.3 0.0 0.26 11.3 0.0 4.3 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.11 KZN87118.1 - 0.0037 16.7 1.5 0.01 15.3 1.5 1.8 1 0 0 1 1 1 1 Lsm interaction motif BRAP2 PF07576.12 KZN87118.1 - 0.0098 16.1 0.1 0.027 14.7 0.1 1.7 1 0 0 1 1 1 1 BRCA1-associated protein 2 DUF4651 PF15513.6 KZN87118.1 - 0.059 13.2 0.1 18 5.2 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) RRM_Rrp7 PF17799.1 KZN87118.1 - 0.061 13.1 0.0 1.8 8.4 0.1 3.0 3 1 1 4 4 4 0 Rrp7 RRM-like N-terminal domain Nup35_RRM PF05172.13 KZN87118.1 - 0.071 13.1 0.0 1.1 9.3 0.0 2.8 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KZN87118.1 - 0.14 12.3 0.2 15 5.8 0.0 3.6 4 0 0 4 4 4 0 RNA recognition motif TPR_14 PF13428.6 KZN87118.1 - 0.21 12.5 3.5 3.9 8.5 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF702 PF05142.12 KZN87118.1 - 1.6 9.2 3.7 5.1 7.6 3.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Ribosomal_L22 PF00237.19 KZN87119.1 - 1.3e-29 102.4 0.1 2.8e-29 101.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_L25p PF01386.19 KZN87119.1 - 0.46 11.0 3.0 1.1 9.8 2.2 2.1 1 1 1 2 2 2 0 Ribosomal L25p family His_Phos_1 PF00300.22 KZN87120.1 - 5.6e-14 52.3 2.3 3.1e-13 49.9 1.0 2.4 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) Pkinase PF00069.25 KZN87122.1 - 3.9e-73 246.1 0.0 4.8e-73 245.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN87122.1 - 6.5e-36 123.9 0.0 8.1e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.11 KZN87122.1 - 8.1e-14 51.5 0.0 1.9e-13 50.3 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 KZN87122.1 - 6.6e-06 25.7 0.0 8.2e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KZN87122.1 - 0.00014 21.6 0.1 0.0003 20.4 0.1 1.5 2 0 0 2 2 2 1 RIO1 family Haspin_kinase PF12330.8 KZN87122.1 - 0.004 16.1 0.2 0.0062 15.5 0.2 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KZN87122.1 - 0.013 14.9 0.3 0.026 13.9 0.3 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KZN87122.1 - 0.016 15.1 0.2 0.071 13.0 0.1 1.9 1 1 0 2 2 2 0 Phosphotransferase enzyme family YukC PF10140.9 KZN87122.1 - 0.045 12.6 0.1 0.063 12.1 0.1 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Pox_ser-thr_kin PF05445.11 KZN87122.1 - 0.076 12.0 0.3 0.11 11.4 0.3 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase AdenylateSensor PF16579.5 KZN87123.1 - 2.5e-19 69.9 0.1 2.1e-12 47.5 0.0 2.4 2 0 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase AAA_16 PF13191.6 KZN87124.1 - 2.9e-08 34.3 1.5 1.5e-07 32.0 0.1 2.6 2 2 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KZN87124.1 - 3.1e-07 30.5 0.7 7.6e-07 29.2 0.1 2.0 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KZN87124.1 - 1.4e-05 25.4 0.8 0.0017 18.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain VRP1 PF03538.14 KZN87124.1 - 0.0065 15.9 0.4 0.01 15.3 0.1 1.6 2 0 0 2 2 2 1 Salmonella virulence plasmid 28.1kDa A protein Zeta_toxin PF06414.12 KZN87124.1 - 0.034 13.4 0.0 0.075 12.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin SMC_N PF02463.19 KZN87124.1 - 0.068 12.6 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Vps54_N PF10475.9 KZN87124.1 - 0.12 11.7 1.6 0.15 11.3 0.2 1.9 3 0 0 3 3 3 0 Vacuolar-sorting protein 54, of GARP complex AAA_29 PF13555.6 KZN87124.1 - 0.16 11.7 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 KZN87124.1 - 0.17 12.4 1.7 0.95 10.0 0.3 2.6 2 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 KZN87124.1 - 0.28 10.4 2.2 4.2 6.5 0.0 2.8 1 1 2 3 3 3 0 KAP family P-loop domain Aldo_ket_red PF00248.21 KZN87125.1 - 1.2e-44 152.7 0.0 1.3e-44 152.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2263 PF10021.9 KZN87125.1 - 0.15 12.4 0.0 0.25 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2263) C2 PF00168.30 KZN87128.1 - 1.7e-15 57.2 0.0 3.2e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain UTP15_C PF09384.10 KZN87129.1 - 2.5e-52 176.4 2.1 2.5e-52 176.4 2.1 1.8 2 0 0 2 2 2 1 UTP15 C terminal WD40 PF00400.32 KZN87129.1 - 8.3e-18 64.4 0.4 0.00037 21.2 0.2 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN87129.1 - 1e-06 28.9 0.3 0.063 13.6 0.0 3.9 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PhyH PF05721.13 KZN87130.1 - 7.1e-45 153.9 0.0 8.5e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MFS_MOT1 PF16983.5 KZN87132.1 - 8.6e-63 209.7 34.3 5.5e-34 116.9 8.2 3.2 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily Sulfate_transp PF00916.20 KZN87132.1 - 0.078 11.7 25.9 2.4e+02 0.2 25.9 2.6 1 1 0 1 1 1 0 Sulfate permease family DUF3087 PF11286.8 KZN87133.1 - 0.19 11.2 0.2 0.33 10.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) Pmp3 PF01679.17 KZN87133.1 - 0.85 9.9 6.1 0.94 9.7 1.1 2.6 2 0 0 2 2 2 0 Proteolipid membrane potential modulator Sec62 PF03839.16 KZN87133.1 - 3.5 7.1 5.4 6.9 6.1 5.4 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 ABC2_membrane PF01061.24 KZN87134.1 - 5.6e-82 274.2 59.1 3.5e-46 157.3 21.5 3.2 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KZN87134.1 - 1.1e-36 126.4 0.0 9.1e-18 65.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KZN87134.1 - 7e-33 112.4 3.5 5.9e-30 103.0 0.1 4.0 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KZN87134.1 - 1.3e-14 54.5 0.2 4.3e-14 52.9 0.2 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 KZN87134.1 - 7.3e-08 32.2 0.0 1.6e-05 24.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KZN87134.1 - 5.5e-07 29.0 48.5 4.3e-06 26.1 19.0 3.2 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_33 PF13671.6 KZN87134.1 - 6.8e-06 26.3 0.1 0.014 15.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KZN87134.1 - 2.6e-05 24.2 0.1 0.0081 16.1 0.0 2.6 3 0 0 3 3 2 1 RsgA GTPase AAA_16 PF13191.6 KZN87134.1 - 3.1e-05 24.4 0.1 0.0062 16.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KZN87134.1 - 0.0007 19.3 1.8 0.05 13.3 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KZN87134.1 - 0.0012 19.4 0.0 0.0088 16.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KZN87134.1 - 0.0034 17.7 0.3 1.6 9.0 0.1 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KZN87134.1 - 0.0067 16.0 1.1 0.038 13.6 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KZN87134.1 - 0.017 15.2 0.0 5.3 7.2 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 KZN87134.1 - 0.044 13.5 1.9 2.6 7.7 0.5 2.9 2 2 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KZN87134.1 - 0.093 12.4 0.0 19 4.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KZN87134.1 - 0.14 12.1 0.1 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 NACHT PF05729.12 KZN87134.1 - 0.28 11.1 2.6 2.7 7.9 0.1 2.7 3 0 0 3 3 2 0 NACHT domain TMEM234 PF10639.9 KZN87136.1 - 4.2e-33 113.8 0.1 2e-25 89.1 0.1 2.1 2 0 0 2 2 2 2 Putative transmembrane family 234 EamA PF00892.20 KZN87136.1 - 0.018 15.2 6.8 0.95 9.6 3.7 2.2 2 0 0 2 2 2 0 EamA-like transporter family Chitin_synth_1 PF01644.17 KZN87137.1 - 4.7e-75 251.0 0.0 7.2e-75 250.4 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KZN87137.1 - 5.9e-28 96.6 0.0 1.2e-27 95.6 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KZN87137.1 - 6.5e-22 77.8 6.1 1e-18 67.3 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KZN87137.1 - 8.1e-07 29.1 3.5 8.1e-07 29.1 3.5 2.7 3 1 0 3 3 3 1 Glycosyl transferase family group 2 FxsA PF04186.13 KZN87137.1 - 0.043 13.9 0.2 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 FxsA cytoplasmic membrane protein TMEM192 PF14802.6 KZN87137.1 - 0.73 8.9 4.3 1.7 7.7 0.0 2.5 2 1 1 3 3 3 0 TMEM192 family LMWPc PF01451.21 KZN87138.1 - 1.7e-33 116.0 0.0 1.8e-26 93.2 0.0 2.1 2 0 0 2 2 2 2 Low molecular weight phosphotyrosine protein phosphatase Spidroin_N PF16763.5 KZN87138.1 - 0.1 12.6 0.1 0.2 11.7 0.0 1.4 2 0 0 2 2 2 0 Major ampullate spidroin 1, spider silk protein 1, N-term COQ7 PF03232.13 KZN87139.1 - 3.9e-67 225.3 0.9 4.6e-67 225.1 0.9 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 KZN87139.1 - 2.7e-07 31.0 2.3 1.7e-06 28.5 0.1 2.1 1 1 1 2 2 2 1 Rubrerythrin UPF0184 PF03670.13 KZN87139.1 - 0.11 12.8 0.6 0.19 12.2 0.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) SPT2 PF08243.11 KZN87139.1 - 0.53 10.8 4.7 0.83 10.2 4.7 1.2 1 0 0 1 1 1 0 SPT2 chromatin protein Plus-3 PF03126.18 KZN87140.1 - 3.3e-31 108.0 0.0 7.7e-30 103.6 0.0 2.6 2 0 0 2 2 2 1 Plus-3 domain MRC1 PF09444.10 KZN87141.1 - 2.6e-39 135.1 22.5 2.6e-39 135.1 22.5 6.7 6 1 1 7 7 7 1 MRC1-like domain KR PF08659.10 KZN87141.1 - 0.001 19.0 1.8 0.0025 17.7 0.7 2.2 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.18 KZN87142.1 - 6.4e-22 78.3 0.0 1.1e-21 77.6 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KZN87142.1 - 6.2e-21 74.8 0.0 1.4e-20 73.7 0.0 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Hydrolase_like PF13242.6 KZN87143.1 - 1.7e-06 28.0 0.1 6.5e-06 26.1 0.0 2.0 3 0 0 3 3 3 1 HAD-hyrolase-like HAD_2 PF13419.6 KZN87143.1 - 0.13 12.4 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase GMC_oxred_N PF00732.19 KZN87144.1 - 1.3e-26 93.7 0.0 2.4e-26 92.8 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KZN87144.1 - 1.9e-19 70.6 0.4 4e-19 69.6 0.4 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KZN87144.1 - 1.3e-07 31.5 3.5 2e-06 27.6 3.5 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KZN87144.1 - 3.5e-07 29.6 1.3 0.0089 15.2 0.5 2.4 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 KZN87144.1 - 1.2e-06 27.5 0.3 3.3e-05 22.8 0.1 2.3 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KZN87144.1 - 1.8e-05 24.2 0.8 0.023 14.0 0.8 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KZN87144.1 - 3.2e-05 23.5 0.1 0.00044 19.7 0.2 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KZN87144.1 - 4.1e-05 23.0 0.1 0.0015 17.9 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KZN87144.1 - 0.00019 21.9 0.2 0.038 14.5 0.1 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN87144.1 - 0.00038 20.6 0.0 0.0017 18.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KZN87144.1 - 0.0015 17.8 0.0 0.0027 17.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KZN87144.1 - 0.0048 16.2 0.1 0.0097 15.2 0.1 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KZN87144.1 - 0.012 14.7 0.0 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KZN87144.1 - 0.018 14.1 0.1 0.033 13.3 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein ILEI PF15711.5 KZN87145.1 - 0.081 13.4 0.4 1.4 9.4 0.1 2.8 3 0 0 3 3 3 0 Interleukin-like EMT inducer G-7-MTase PF12803.7 KZN87146.1 - 0.0029 16.8 0.0 0.0069 15.6 0.0 1.5 2 0 0 2 2 2 1 mRNA (guanine-7-)methyltransferase (G-7-MTase) DUF3638 PF12340.8 KZN87150.1 - 5.9e-87 290.7 0.1 1.2e-86 289.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KZN87150.1 - 1.5e-16 59.5 0.1 4.7e-16 57.9 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) FAD_binding_3 PF01494.19 KZN87151.1 - 1.9e-18 66.8 0.0 6e-10 38.9 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KZN87151.1 - 1.7e-06 28.2 0.4 4e-06 27.0 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KZN87151.1 - 0.00049 19.8 0.4 0.0037 16.9 0.2 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KZN87151.1 - 0.0085 15.4 0.2 0.02 14.1 0.2 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KZN87151.1 - 0.018 14.1 1.6 0.033 13.3 0.6 1.9 3 0 0 3 3 3 0 FAD binding domain Trp_halogenase PF04820.14 KZN87151.1 - 0.13 11.0 0.4 0.21 10.4 0.4 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Acetyltransf_2 PF00797.17 KZN87152.1 - 3e-43 148.4 0.0 5.2e-43 147.6 0.0 1.4 1 1 0 1 1 1 1 N-acetyltransferase MIF4G PF02854.19 KZN87154.1 - 4.2e-20 72.3 0.0 8.4e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 KZN87154.1 - 2.7e-19 69.2 0.0 8.9e-19 67.5 0.0 2.0 2 0 0 2 2 2 1 MA3 domain SRP14 PF02290.15 KZN87155.1 - 2.3e-27 95.2 0.0 3.3e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Vps36_ESCRT-II PF11605.8 KZN87155.1 - 0.074 13.2 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 Inp1 PF12634.7 KZN87156.1 - 6.5e-40 136.3 0.0 1.5e-39 135.1 0.0 1.7 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 EI24 PF07264.11 KZN87157.1 - 2.3e-12 47.5 5.3 4.3e-05 23.8 0.0 2.2 1 1 0 2 2 2 2 Etoposide-induced protein 2.4 (EI24) DUF1700 PF08006.11 KZN87157.1 - 5.6 6.5 8.7 19 4.7 3.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) FmdA_AmdA PF03069.15 KZN87158.1 - 3.6e-178 592.1 0.0 4.1e-178 591.9 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Tyr_Deacylase PF02580.16 KZN87159.1 - 8.5e-52 175.5 0.0 1.1e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Not3 PF04065.15 KZN87160.1 - 5.4e-87 291.0 18.0 7.7e-87 290.5 18.0 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KZN87160.1 - 4.4e-44 149.8 11.5 8.9e-44 148.7 11.5 1.6 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 KZN87160.1 - 0.029 14.7 2.1 0.029 14.7 2.1 2.3 3 0 0 3 3 3 0 Syntaxin-like protein Snapin_Pallidin PF14712.6 KZN87160.1 - 0.055 13.9 0.7 0.055 13.9 0.7 2.6 2 1 1 3 3 3 0 Snapin/Pallidin Cep57_MT_bd PF06657.13 KZN87160.1 - 0.065 13.7 9.4 0.26 11.8 0.7 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF2373 PF10180.9 KZN87160.1 - 0.069 13.0 5.4 0.03 14.2 2.4 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2373) FlaC_arch PF05377.11 KZN87160.1 - 0.13 12.6 3.0 2.6 8.5 0.0 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF1192 PF06698.11 KZN87160.1 - 0.14 12.2 2.9 0.43 10.7 1.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) LZ_Tnp_IS66 PF13007.7 KZN87160.1 - 0.15 12.8 7.0 2.4 9.0 0.2 3.7 3 0 0 3 3 3 0 Transposase C of IS166 homeodomain zf-C2H2 PF00096.26 KZN87161.1 - 0.00014 22.1 18.0 0.00016 21.9 1.3 3.6 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KZN87161.1 - 0.0028 18.4 1.2 0.0028 18.4 1.2 3.6 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2HE PF16278.5 KZN87161.1 - 0.004 17.6 0.1 0.048 14.1 0.0 2.2 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger GFA PF04828.14 KZN87161.1 - 0.066 13.6 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zf-C2H2_11 PF16622.5 KZN87161.1 - 0.088 12.6 0.9 0.088 12.6 0.9 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type DNA_binding_1 PF01035.20 KZN87162.1 - 3.3e-27 94.4 0.0 5e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Pex14_N PF04695.13 KZN87162.1 - 0.36 11.5 5.3 0.48 11.1 5.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sugar_tr PF00083.24 KZN87163.1 - 1.3e-85 287.9 22.9 1.6e-85 287.7 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN87163.1 - 8.9e-20 70.9 50.0 1.9e-14 53.4 21.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_16 PF00722.21 KZN87164.1 - 4.1e-06 26.4 0.1 6.7e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MFS_1 PF07690.16 KZN87165.1 - 2.8e-43 148.2 22.9 4.4e-43 147.5 22.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN87165.1 - 1.2e-07 31.0 10.3 1.2e-07 31.0 10.3 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KZN87165.1 - 0.00016 20.3 4.9 0.00024 19.7 4.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) nsp9 PF08710.10 KZN87165.1 - 0.034 14.5 0.0 0.061 13.7 0.0 1.3 1 0 0 1 1 1 0 nsp9 replicase Pyr_redox_2 PF07992.14 KZN87166.1 - 5.1e-69 232.7 8.1 5.1e-69 232.7 8.1 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KZN87166.1 - 4.9e-41 139.4 1.0 1.2e-40 138.2 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KZN87166.1 - 9.9e-21 74.1 8.4 7.5e-19 68.1 0.8 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KZN87166.1 - 8.5e-11 41.8 8.2 2.5e-10 40.3 0.7 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KZN87166.1 - 5e-10 39.5 4.9 2.5e-05 24.4 0.4 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KZN87166.1 - 1.7e-08 34.0 15.9 2.5e-07 30.1 5.6 3.5 2 2 1 3 3 3 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KZN87166.1 - 9.5e-08 31.6 7.0 6.2e-06 25.7 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KZN87166.1 - 3.8e-07 29.6 2.5 3.8e-07 29.6 2.5 3.0 2 1 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 KZN87166.1 - 5.5e-07 29.1 5.7 0.00084 18.7 1.1 3.1 3 1 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 KZN87166.1 - 3.7e-06 26.3 0.4 0.014 14.5 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KZN87166.1 - 0.00018 21.2 14.3 0.043 13.4 0.4 4.1 3 1 1 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KZN87166.1 - 0.00031 19.6 1.7 0.00031 19.6 1.7 3.8 4 0 0 4 4 4 1 HI0933-like protein Lycopene_cycl PF05834.12 KZN87166.1 - 0.00055 19.1 0.6 0.028 13.5 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KZN87166.1 - 0.004 16.4 1.8 0.004 16.4 1.8 2.5 1 1 1 2 2 2 1 Thi4 family FMO-like PF00743.19 KZN87166.1 - 0.11 10.9 0.9 0.57 8.5 0.1 2.3 2 1 1 3 3 3 0 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.19 KZN87166.1 - 0.12 11.6 10.1 0.54 9.4 0.8 3.0 3 1 0 3 3 3 0 FAD binding domain NAD_binding_7 PF13241.6 KZN87166.1 - 0.13 12.7 3.4 0.32 11.4 0.3 3.0 3 1 0 3 3 3 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 KZN87166.1 - 6.4 5.5 7.5 1.2 7.9 0.7 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Asparaginase PF00710.20 KZN87167.1 - 3.5e-48 163.7 1.7 6.2e-48 162.9 1.7 1.4 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KZN87167.1 - 4.9e-20 71.9 0.0 1e-19 70.8 0.0 1.6 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain HEAT_2 PF13646.6 KZN87168.1 - 4.8e-21 74.9 8.5 1.5e-05 25.3 0.0 5.8 4 1 1 5 5 5 4 HEAT repeats NACHT PF05729.12 KZN87168.1 - 3.9e-15 56.2 0.1 1.7e-14 54.1 0.0 2.2 2 0 0 2 2 2 1 NACHT domain HEAT PF02985.22 KZN87168.1 - 4.2e-15 54.5 9.9 0.55 10.6 0.0 8.8 9 0 0 9 9 9 5 HEAT repeat HEAT_EZ PF13513.6 KZN87168.1 - 9.4e-10 38.8 3.4 0.036 14.6 0.1 6.2 5 3 1 6 6 6 3 HEAT-like repeat NLRC4_HD2 PF17776.1 KZN87168.1 - 1.3e-07 32.2 3.8 0.00044 20.8 0.4 3.3 1 1 1 2 2 2 2 NLRC4 helical domain HD2 Cohesin_HEAT PF12765.7 KZN87168.1 - 4e-07 30.2 6.6 3.9e-05 23.9 0.1 3.6 3 1 1 4 4 3 2 HEAT repeat associated with sister chromatid cohesion NB-ARC PF00931.22 KZN87168.1 - 6.5e-07 28.8 0.0 2.9e-05 23.4 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain Adaptin_N PF01602.20 KZN87168.1 - 1.4e-06 27.2 8.9 0.034 12.7 0.2 4.6 4 1 1 5 5 5 3 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 KZN87168.1 - 3.6e-05 24.3 1.4 1 10.0 0.1 5.2 4 1 0 4 4 4 1 Vacuolar 14 Fab1-binding region AAA_22 PF13401.6 KZN87168.1 - 0.00033 20.9 0.0 0.0014 18.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain TolA PF06519.11 KZN87168.1 - 0.0013 18.9 0.0 0.23 11.7 0.0 2.8 2 0 0 2 2 2 1 TolA C-terminal Cnd1 PF12717.7 KZN87168.1 - 0.0041 17.2 14.5 0.48 10.5 0.4 5.3 4 2 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 AAA PF00004.29 KZN87168.1 - 0.0049 17.3 0.0 0.017 15.5 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) V-ATPase_H_C PF11698.8 KZN87168.1 - 0.026 14.6 3.1 4.2 7.5 0.1 4.7 4 0 0 4 4 4 0 V-ATPase subunit H NTPase_1 PF03266.15 KZN87168.1 - 0.037 14.0 0.1 0.13 12.1 0.1 2.0 1 0 0 1 1 1 0 NTPase AAA_16 PF13191.6 KZN87168.1 - 0.099 13.0 1.1 0.38 11.1 0.3 2.4 2 1 0 2 2 1 0 AAA ATPase domain AAA_18 PF13238.6 KZN87168.1 - 0.15 12.6 0.1 0.5 10.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain FAST_2 PF08368.12 KZN87168.1 - 0.21 12.4 0.6 16 6.4 0.1 3.6 3 0 0 3 3 2 0 FAST kinase-like protein, subdomain 2 GTP_cyclohydroI PF01227.22 KZN87173.1 - 2.8e-70 235.4 0.2 3.5e-70 235.1 0.2 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KZN87173.1 - 0.0019 18.3 0.0 0.0034 17.5 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein HATPase_c_2 PF13581.6 KZN87173.1 - 0.16 12.0 0.1 0.31 11.0 0.1 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain P-mevalo_kinase PF04275.14 KZN87174.1 - 8.9e-22 77.2 0.0 1.4e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Phosphomevalonate kinase Pribosyltran PF00156.27 KZN87174.1 - 1.9e-21 76.3 0.0 3.2e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FAD_binding_4 PF01565.23 KZN87174.1 - 9.8e-14 51.3 1.7 2.4e-13 50.0 1.7 1.7 1 0 0 1 1 1 1 FAD binding domain UPRTase PF14681.6 KZN87174.1 - 0.0059 16.1 0.1 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase BBE PF08031.12 KZN87174.1 - 0.017 15.2 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like PRTase_2 PF15609.6 KZN87174.1 - 0.019 14.5 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase Aegerolysin PF06355.13 KZN87175.1 - 2.7e-30 105.2 1.7 3.2e-30 104.9 1.7 1.1 1 0 0 1 1 1 1 Aegerolysin SET PF00856.28 KZN87177.1 - 2.5e-15 57.3 0.0 8.3e-14 52.3 0.0 2.8 2 1 0 2 2 2 1 SET domain TPR_1 PF00515.28 KZN87177.1 - 2.5e-10 39.7 0.1 2e-06 27.4 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KZN87177.1 - 9.4e-08 31.6 0.3 0.0018 18.3 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KZN87177.1 - 1e-06 29.0 0.2 0.091 13.6 0.0 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KZN87177.1 - 2e-06 27.6 0.4 0.0022 18.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KZN87177.1 - 5.4e-05 22.9 0.0 0.12 12.4 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KZN87177.1 - 0.00016 22.2 1.9 0.0014 19.3 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KZN87177.1 - 0.00045 19.9 0.0 0.0019 17.8 0.0 2.1 2 0 0 2 2 2 1 TPR repeat ANAPC3 PF12895.7 KZN87177.1 - 0.0017 18.6 2.1 0.0028 17.9 0.5 2.3 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KZN87177.1 - 0.0044 17.6 1.0 1.4 9.7 0.2 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat YfiO PF13525.6 KZN87177.1 - 0.0049 16.6 0.3 0.032 13.9 0.0 2.0 1 1 1 2 2 2 1 Outer membrane lipoprotein TPR_12 PF13424.6 KZN87177.1 - 0.014 15.7 2.0 1.2 9.5 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KZN87177.1 - 0.034 14.7 3.9 2.4 8.7 1.7 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KZN87177.1 - 0.13 12.3 0.2 0.36 10.9 0.2 1.8 1 0 0 1 1 1 0 Putative TPR-like repeat MFS_1 PF07690.16 KZN87179.1 - 1.4e-30 106.4 39.5 1.8e-30 106.1 39.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN87179.1 - 2.4e-09 36.6 13.9 5.4e-09 35.4 13.9 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KZN87179.1 - 1.5e-06 27.0 1.5 2e-06 26.5 1.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KZN87179.1 - 0.0031 15.9 8.5 0.0053 15.1 8.5 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family SKG6 PF08693.10 KZN87181.1 - 0.00042 19.7 1.7 0.00085 18.7 1.7 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM51 PF15345.6 KZN87181.1 - 0.0047 16.8 0.0 0.0064 16.4 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 DUF5305 PF17231.2 KZN87181.1 - 0.085 12.3 0.1 0.11 11.9 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) EphA2_TM PF14575.6 KZN87181.1 - 0.15 12.9 0.0 0.3 12.0 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Med21 PF11221.8 KZN87181.1 - 0.5 10.6 6.5 0.87 9.8 6.5 1.4 1 1 0 1 1 1 0 Subunit 21 of Mediator complex Gram_pos_anchor PF00746.21 KZN87181.1 - 0.84 9.6 4.3 4.3 7.4 4.3 2.1 1 1 0 1 1 1 0 LPXTG cell wall anchor motif MGC-24 PF05283.11 KZN87181.1 - 1.3 9.5 11.6 0.35 11.3 8.4 1.9 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Sad1_UNC PF07738.13 KZN87182.1 - 0.052 13.6 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal Pkinase PF00069.25 KZN87184.1 - 1.8e-10 40.7 0.0 2.6e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KZN87184.1 - 2.2e-07 31.0 0.1 2.9e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KZN87184.1 - 2.4e-06 27.0 0.1 3.3e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KZN87184.1 - 0.00014 21.2 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KZN87184.1 - 0.00036 20.2 0.0 0.00061 19.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KZN87184.1 - 0.0076 15.1 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 KZN87184.1 - 0.03 13.9 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase PGM_PMM_II PF02879.16 KZN87185.1 - 5.5e-24 84.8 0.0 1.5e-23 83.4 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_I PF02878.16 KZN87185.1 - 3.4e-23 81.9 0.1 7.3e-23 80.8 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KZN87185.1 - 3.1e-17 62.8 0.1 6.5e-17 61.8 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 KZN87185.1 - 2.5e-07 30.8 0.1 9.7e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain FA_desaturase PF00487.24 KZN87186.1 - 4.2e-26 92.3 25.7 5.9e-26 91.8 25.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KZN87186.1 - 1.7e-11 44.1 0.0 3.5e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Unstab_antitox PF09720.10 KZN87186.1 - 0.012 15.6 0.9 0.27 11.3 0.0 2.7 3 0 0 3 3 3 0 Putative addiction module component CUE PF02845.16 KZN87187.1 - 1.8e-06 27.5 0.1 3.5e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 CUE domain Ribosomal_S10 PF00338.22 KZN87188.1 - 1.1e-25 89.7 0.3 1.3e-25 89.5 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e zf-CCCH_4 PF18044.1 KZN87189.1 - 2.2e-08 33.7 3.2 4.1e-08 32.9 3.2 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 KZN87189.1 - 4.5e-07 29.6 2.9 9.8e-07 28.5 2.9 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KZN87189.1 - 1.3e-06 28.2 7.2 3e-06 27.1 7.2 1.6 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 KZN87189.1 - 0.058 14.1 0.7 0.1 13.3 0.7 1.4 1 0 0 1 1 1 0 Torus domain zf-CCCH_2 PF14608.6 KZN87189.1 - 0.11 13.0 4.7 0.23 12.0 4.7 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Nucleoporin_FG PF13634.6 KZN87189.1 - 2.3 9.1 83.9 2.9 8.8 21.4 5.6 2 2 1 3 3 3 0 Nucleoporin FG repeat region ELYS PF13934.6 KZN87190.1 - 1.3e-68 231.3 1.3 1.5e-68 231.0 1.3 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly Thioredoxin_8 PF13905.6 KZN87190.1 - 0.099 13.0 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like SMC_N PF02463.19 KZN87191.1 - 1.8e-77 259.7 1.7 4.8e-77 258.3 1.7 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KZN87191.1 - 2.9e-24 85.6 0.0 2.5e-23 82.6 0.0 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KZN87191.1 - 5.3e-13 49.5 2.3 4.8e-05 23.3 0.0 4.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF3584 PF12128.8 KZN87191.1 - 0.00015 19.5 47.0 0.00015 19.5 47.0 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3584) AAA_29 PF13555.6 KZN87191.1 - 0.00056 19.6 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Cob_adeno_trans PF01923.18 KZN87191.1 - 0.00083 19.5 1.9 0.00083 19.5 1.9 6.1 3 2 1 5 5 5 1 Cobalamin adenosyltransferase DUF5082 PF16888.5 KZN87191.1 - 0.0022 18.3 0.3 0.0022 18.3 0.3 8.4 3 2 5 8 8 8 2 Domain of unknown function (DUF5082) ATG16 PF08614.11 KZN87191.1 - 0.0025 18.1 12.0 0.0025 18.1 12.0 7.7 3 2 5 8 8 8 2 Autophagy protein 16 (ATG16) SbcCD_C PF13558.6 KZN87191.1 - 0.025 14.8 0.0 0.71 10.1 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 KZN87191.1 - 1.5 9.3 0.0 1.5 9.3 0.0 5.5 4 2 0 5 5 5 0 ABC transporter Glyco_hydro_16 PF00722.21 KZN87193.1 - 3.9e-43 147.0 5.0 6.5e-43 146.3 5.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 p450 PF00067.22 KZN87194.1 - 4e-82 276.4 0.0 5.2e-82 276.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KZN87194.1 - 8.1e-26 91.0 0.0 1.2e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KZN87194.1 - 2.5e-24 86.1 0.1 1.4e-23 83.7 0.1 2.2 3 0 0 3 3 3 1 Flavodoxin NAD_binding_1 PF00175.21 KZN87194.1 - 1.3e-08 35.4 0.0 2.9e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KZN87194.1 - 0.0012 19.1 0.0 0.0022 18.2 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain DUF550 PF04447.12 KZN87194.1 - 0.17 12.0 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF550) FMO-like PF00743.19 KZN87195.1 - 2.5e-28 98.8 0.0 1.4e-13 50.2 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KZN87195.1 - 4.2e-13 49.2 0.0 4.3e-05 22.9 0.0 3.1 2 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KZN87195.1 - 6.4e-12 45.3 2.5 1e-08 34.8 0.1 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KZN87195.1 - 2.2e-06 27.7 2.6 0.0018 18.3 0.0 3.6 3 1 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KZN87195.1 - 1.5e-05 25.1 0.0 4.6e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KZN87195.1 - 8.5e-05 21.9 0.4 0.013 14.7 0.0 2.7 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KZN87195.1 - 0.0093 15.6 1.9 2.3 7.7 0.3 2.5 2 1 1 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 KZN87195.1 - 0.1 11.8 0.1 0.23 10.7 0.1 1.6 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KZN87195.1 - 0.27 9.9 0.2 0.71 8.5 0.3 1.6 2 0 0 2 2 2 0 HI0933-like protein adh_short_C2 PF13561.6 KZN87196.1 - 1.6e-55 188.2 1.7 1.9e-55 188.0 1.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN87196.1 - 2.5e-39 134.8 2.2 3.3e-39 134.4 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN87196.1 - 2.1e-10 40.8 2.1 3.2e-10 40.2 2.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KZN87196.1 - 0.029 14.2 0.1 0.052 13.4 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KZN87196.1 - 0.038 13.4 0.1 0.055 12.8 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HHH_5 PF14520.6 KZN87196.1 - 0.048 14.3 0.1 0.16 12.6 0.1 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix domain Glyco_hydro_43 PF04616.14 KZN87197.1 - 1.9e-37 129.1 0.6 2.4e-37 128.8 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Fungal_trans PF04082.18 KZN87198.1 - 2.3e-10 39.9 2.1 5.5e-10 38.7 1.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN87198.1 - 1.5e-09 37.8 7.5 3.1e-09 36.8 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Suc_Fer-like PF06999.12 KZN87199.1 - 4.8e-69 232.1 0.0 5.7e-69 231.9 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Flavi_NS4A PF01350.17 KZN87199.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A PhyH PF05721.13 KZN87200.1 - 1.1e-12 48.7 0.0 7.3e-12 46.0 0.0 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AA_permease PF00324.21 KZN87201.1 - 6.8e-50 170.0 12.2 9.2e-50 169.6 12.2 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.11 KZN87201.1 - 0.0087 16.4 0.8 0.0087 16.4 0.8 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF1772) DUF3751 PF12571.8 KZN87201.1 - 0.096 12.8 0.2 0.15 12.1 0.2 1.2 1 0 0 1 1 1 0 Phage tail-collar fibre protein DUF805 PF05656.14 KZN87201.1 - 2.6 8.5 5.9 11 6.5 5.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Drc1-Sld2 PF11719.8 KZN87202.1 - 2.2e-118 396.7 32.7 4.7e-118 395.6 32.7 1.5 1 1 0 1 1 1 1 DNA replication and checkpoint protein zf-RING_2 PF13639.6 KZN87204.1 - 1.6e-07 31.5 11.0 2.7e-07 30.8 11.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KZN87204.1 - 7.7e-06 25.7 6.5 1.2e-05 25.1 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KZN87204.1 - 1.1e-05 25.2 10.3 1.7e-05 24.6 10.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KZN87204.1 - 2.1e-05 24.3 11.6 3.4e-05 23.6 11.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KZN87204.1 - 0.00042 20.5 10.1 0.0013 19.0 10.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KZN87204.1 - 0.3 11.1 8.2 0.69 10.0 8.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 KZN87204.1 - 0.44 10.6 3.4 0.64 10.1 2.5 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KZN87204.1 - 3.1 7.6 7.0 6.5 6.6 7.0 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-Nse PF11789.8 KZN87204.1 - 4.5 7.2 7.9 3.5 7.5 6.4 1.6 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit HAD_SAK_1 PF10307.9 KZN87205.1 - 1.6e-77 259.9 0.0 2.2e-77 259.5 0.0 1.2 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins API5 PF05918.11 KZN87205.1 - 7 5.3 9.0 12 4.6 9.0 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Fig1 PF12351.8 KZN87207.1 - 3.8e-59 199.8 5.1 3.8e-59 199.8 5.1 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 KZN87207.1 - 3.1e-06 27.0 8.8 3.1e-06 27.0 8.8 1.8 1 1 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.13 KZN87207.1 - 0.00043 19.5 5.1 0.00043 19.5 5.1 1.7 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) DUF2207 PF09972.9 KZN87207.1 - 0.08 11.7 12.3 0.22 10.3 0.1 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) XPG_I PF00867.18 KZN87208.1 - 6.1e-24 84.2 0.1 1.1e-23 83.3 0.1 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KZN87208.1 - 2.6e-23 82.4 0.0 1.8e-22 79.7 0.0 2.2 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.7 KZN87208.1 - 8.4e-05 22.2 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing TBX PF12598.8 KZN87208.1 - 8.5 7.3 9.5 0.29 12.0 1.6 2.6 2 1 0 2 2 2 0 T-box transcription factor Tma16 PF11176.8 KZN87209.1 - 5.6e-51 172.3 3.0 6.8e-51 172.0 3.0 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 DUF4777 PF16007.5 KZN87209.1 - 0.048 13.9 0.2 0.49 10.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) CDC73_N PF16050.5 KZN87209.1 - 0.13 11.6 4.3 0.15 11.4 4.3 1.2 1 0 0 1 1 1 0 Paf1 complex subunit CDC73 N-terminal MAM33 PF02330.16 KZN87210.1 - 8.2e-68 228.5 7.8 9.7e-68 228.3 7.8 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein T3SS_needle_E PF08988.10 KZN87210.1 - 0.016 15.3 0.8 0.046 13.9 0.2 2.0 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle DNA_primase_S PF01896.19 KZN87211.1 - 7.1e-58 195.5 0.0 9.9e-58 195.1 0.0 1.2 1 0 0 1 1 1 1 DNA primase small subunit Profilin PF00235.19 KZN87213.1 - 2.9e-22 79.3 0.1 3.4e-22 79.1 0.1 1.0 1 0 0 1 1 1 1 Profilin Sugar_tr PF00083.24 KZN87214.1 - 1.5e-77 261.4 22.3 1.8e-77 261.1 22.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN87214.1 - 6.6e-18 64.8 52.0 2.2e-14 53.2 25.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2456 PF10445.9 KZN87214.1 - 7.6 6.7 12.1 1.5 9.0 0.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2456) Thr_synth_N PF14821.6 KZN87215.1 - 1.3e-29 102.2 0.0 7.8e-29 99.7 0.0 2.2 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 KZN87215.1 - 3.6e-12 46.3 0.0 2.1e-11 43.8 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_N PF08240.12 KZN87216.1 - 9.7e-24 83.4 6.4 1.7e-23 82.6 6.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN87216.1 - 6e-17 61.9 0.0 9.9e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KZN87216.1 - 3.8e-09 37.7 0.0 5.8e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KZN87216.1 - 0.0086 15.4 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KZN87216.1 - 0.084 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Adaptin_N PF01602.20 KZN87217.1 - 7.9e-138 460.3 1.9 1e-137 459.9 1.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KZN87217.1 - 1.4e-64 217.1 0.4 6.6e-60 201.8 0.4 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KZN87217.1 - 1.5e-16 60.6 4.8 3.8e-06 27.2 0.0 6.2 3 2 2 6 6 6 4 HEAT repeats HEAT PF02985.22 KZN87217.1 - 2.8e-12 45.8 3.5 0.022 15.0 0.0 6.9 7 0 0 7 7 6 2 HEAT repeat CLASP_N PF12348.8 KZN87217.1 - 7.7e-05 22.4 0.4 0.65 9.5 0.0 4.1 3 1 1 4 4 4 2 CLASP N terminal HEAT_EZ PF13513.6 KZN87217.1 - 0.00068 20.1 5.7 0.6 10.7 0.0 6.4 7 1 1 8 8 8 1 HEAT-like repeat RTP1_C1 PF10363.9 KZN87217.1 - 0.0035 17.5 0.6 1.2 9.3 0.0 4.1 3 2 1 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 KZN87217.1 - 0.0038 17.2 1.5 40 4.4 0.0 5.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat UNC45-central PF11701.8 KZN87217.1 - 0.042 13.8 0.2 0.19 11.7 0.0 2.2 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central CAAP1 PF15335.6 KZN87217.1 - 0.55 10.8 2.5 0.82 10.3 0.1 2.5 3 0 0 3 3 2 0 Caspase activity and apoptosis inhibitor 1 DUF5578 PF17741.1 KZN87217.1 - 1.1 8.6 8.0 31 3.8 0.1 4.1 2 1 1 4 4 4 0 Family of unknown function (DUF5578) Ribosomal_60s PF00428.19 KZN87217.1 - 3.5 8.3 10.0 24 5.6 6.7 3.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF5310 PF17237.2 KZN87218.1 - 1.8e-20 72.5 1.0 2.7e-20 72.0 1.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5310) Vps55 PF04133.14 KZN87218.1 - 0.13 12.3 0.1 0.18 11.8 0.1 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting 55 L27_2 PF09045.10 KZN87218.1 - 0.2 11.6 0.2 5.1 7.1 0.2 2.3 1 1 0 1 1 1 0 L27_2 DEK_C PF08766.11 KZN87219.1 - 0.00028 20.8 0.0 0.00072 19.4 0.0 1.7 1 0 0 1 1 1 1 DEK C terminal domain DUF4733 PF15878.5 KZN87219.1 - 0.14 12.6 5.5 0.071 13.6 1.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4733) Evr1_Alr PF04777.13 KZN87220.1 - 1.4e-27 96.1 3.7 1.4e-27 96.1 3.7 1.6 2 0 0 2 2 2 1 Erv1 / Alr family Bd3614-deam PF14439.6 KZN87220.1 - 0.09 12.8 0.0 4.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Bd3614-like deaminase Coatomer_WDAD PF04053.14 KZN87221.1 - 1.8e-148 495.3 0.0 6e-148 493.6 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.11 KZN87221.1 - 3.2e-108 362.1 0.0 4.6e-108 361.6 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KZN87221.1 - 1.3e-38 130.3 12.4 3.7e-08 33.9 0.1 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN87221.1 - 1.5e-07 31.6 0.5 1.2 9.5 0.0 6.2 3 3 5 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KZN87221.1 - 0.016 13.9 8.2 1.5 7.4 0.2 4.0 3 1 1 4 4 4 0 Nucleoporin Nup120/160 TBCC PF07986.12 KZN87223.1 - 4.4e-33 113.5 0.5 6.6e-33 113.0 0.5 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 KZN87223.1 - 1.3e-06 28.8 0.1 2.2e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain RTX PF02382.15 KZN87223.1 - 0.085 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in RTX protein Pro-kuma_activ PF09286.11 KZN87224.1 - 7.8e-35 120.2 0.1 2e-34 118.9 0.0 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KZN87224.1 - 0.0016 17.8 0.2 0.0028 17.0 0.2 1.4 1 0 0 1 1 1 1 Subtilase family DUF5390 PF17365.2 KZN87224.1 - 0.082 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5390) CSN8_PSD8_EIF3K PF10075.9 KZN87225.1 - 1.2e-18 67.4 0.0 1.9e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family MFS_1 PF07690.16 KZN87227.1 - 7.2e-37 127.1 30.9 7.8e-33 113.8 23.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KZN87227.1 - 2.3e-06 27.1 13.1 0.0004 19.8 7.0 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KZN87227.1 - 0.0012 17.3 7.2 0.0043 15.4 3.0 2.8 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 KZN87227.1 - 0.0017 17.3 16.0 0.65 8.8 0.0 3.6 3 1 0 3 3 3 2 MFS_1 like family PNTB PF02233.16 KZN87227.1 - 0.079 11.9 2.2 0.15 11.0 2.2 1.3 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit EHN PF06441.12 KZN87228.1 - 8.9e-35 119.3 0.1 1.6e-34 118.5 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KZN87228.1 - 8.7e-10 38.7 0.0 1.5e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KZN87228.1 - 0.0038 17.9 4.0 0.027 15.1 0.4 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Tugs PF17840.1 KZN87228.1 - 0.18 12.0 0.0 0.97 9.7 0.0 2.1 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain DUF1917 PF08939.10 KZN87229.1 - 3.8e-88 295.8 0.0 4.4e-88 295.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) Vps51 PF08700.11 KZN87230.1 - 1.9e-27 95.2 0.0 4.2e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 KZN87230.1 - 0.01 14.5 0.2 0.013 14.2 0.2 1.1 1 0 0 1 1 1 0 Dor1-like family COG5 PF10392.9 KZN87230.1 - 0.023 14.8 0.0 0.049 13.8 0.0 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 RMI1_N PF08585.12 KZN87231.1 - 7.9e-64 215.4 0.0 9e-64 215.2 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein TPR_2 PF07719.17 KZN87232.1 - 7.2e-26 88.2 37.0 0.00014 21.7 0.1 15.3 15 0 0 15 15 14 6 Tetratricopeptide repeat TPR_1 PF00515.28 KZN87232.1 - 2.8e-25 87.1 23.8 0.0001 21.9 0.0 11.9 12 0 0 12 12 11 7 Tetratricopeptide repeat TPR_14 PF13428.6 KZN87232.1 - 3.6e-25 86.5 36.4 2.9e-06 27.6 0.3 15.5 11 5 6 17 17 14 3 Tetratricopeptide repeat TPR_8 PF13181.6 KZN87232.1 - 6.6e-25 85.2 22.4 9.3e-05 22.3 0.0 13.2 13 0 0 13 13 11 5 Tetratricopeptide repeat TPR_17 PF13431.6 KZN87232.1 - 7.3e-24 82.4 12.0 0.14 12.6 0.0 13.6 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_16 PF13432.6 KZN87232.1 - 7e-23 81.0 38.5 0.0001 22.9 0.5 11.2 11 1 1 12 12 11 6 Tetratricopeptide repeat TPR_19 PF14559.6 KZN87232.1 - 4.3e-21 75.2 22.4 4.5e-05 23.9 0.6 10.5 9 2 2 11 11 11 5 Tetratricopeptide repeat TPR_11 PF13414.6 KZN87232.1 - 5.5e-16 58.0 13.2 0.00059 19.5 0.1 9.5 9 1 1 10 10 10 4 TPR repeat TPR_7 PF13176.6 KZN87232.1 - 6.8e-12 44.5 14.5 0.0051 16.7 0.1 9.0 10 1 1 11 11 10 2 Tetratricopeptide repeat TPR_6 PF13174.6 KZN87232.1 - 1.5e-11 44.1 26.6 3.8e-05 24.0 0.2 11.9 14 1 0 14 14 11 2 Tetratricopeptide repeat TPR_12 PF13424.6 KZN87232.1 - 2.5e-11 43.7 38.7 8.7e-07 29.2 1.5 10.8 10 3 2 12 12 11 3 Tetratricopeptide repeat TPR_9 PF13371.6 KZN87232.1 - 1.7e-07 31.3 10.5 0.51 10.5 0.4 7.4 6 2 1 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KZN87232.1 - 6.8e-06 26.2 14.2 0.039 14.2 1.6 6.2 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_22 PF18833.1 KZN87232.1 - 7.1e-06 26.1 0.0 2.2e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KZN87232.1 - 0.011 15.1 8.7 0.15 11.4 1.1 3.7 3 0 0 3 3 3 0 MalT-like TPR region TPR_10 PF13374.6 KZN87232.1 - 0.016 15.0 19.1 0.53 10.2 0.7 7.4 9 0 0 9 9 7 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KZN87232.1 - 0.067 12.8 0.4 15 5.3 0.0 3.0 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) COX17 PF05051.13 KZN87232.1 - 0.14 12.5 0.1 0.37 11.2 0.1 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Glyco_hydro_5_C PF18564.1 KZN87233.1 - 4.4e-22 78.4 0.0 1e-21 77.2 0.0 1.7 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KZN87233.1 - 2.8e-08 33.5 5.5 4.5e-07 29.6 3.3 2.7 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 KZN87233.1 - 0.0096 15.3 1.7 0.75 9.1 0.1 2.2 2 0 0 2 2 2 2 Beta-galactosidase Glyco_hydro_35 PF01301.19 KZN87233.1 - 0.072 12.7 0.4 0.13 11.9 0.4 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 EKLF_TAD1 PF16832.5 KZN87233.1 - 0.079 12.8 0.8 0.24 11.3 0.8 1.8 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 1 Xpo1 PF08389.12 KZN87234.1 - 5.6e-12 45.9 1.0 1.8e-05 24.8 0.0 3.9 3 0 0 3 3 3 2 Exportin 1-like protein IBN_N PF03810.19 KZN87234.1 - 0.075 13.0 0.5 0.77 9.7 0.1 3.1 2 1 1 3 3 3 0 Importin-beta N-terminal domain GRIM-19 PF06212.12 KZN87235.1 - 1e-23 83.8 0.5 3.4e-23 82.0 0.5 1.7 1 1 0 1 1 1 1 GRIM-19 protein tRNA_m1G_MT PF01746.21 KZN87236.1 - 1.1e-25 90.5 0.0 1.6e-24 86.7 0.0 2.4 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase VID27 PF08553.10 KZN87237.1 - 6.1e-195 647.2 0.1 8.5e-195 646.7 0.1 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 KZN87237.1 - 4.5e-75 251.2 0.1 4.5e-75 251.2 0.1 2.8 3 1 0 3 3 3 1 VID27 N-terminal region VID27_PH PF17747.1 KZN87237.1 - 4.7e-48 162.0 2.3 1.8e-47 160.1 1.5 2.2 2 0 0 2 2 2 1 VID27 PH-like domain UPF0149 PF03695.13 KZN87237.1 - 0.067 13.5 3.1 0.17 12.2 2.2 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0149) SOUL PF04832.12 KZN87238.1 - 0.14 12.4 0.0 0.37 11.0 0.0 1.7 2 0 0 2 2 2 0 SOUL heme-binding protein Acetyltransf_10 PF13673.7 KZN87239.1 - 2.6e-07 30.6 0.0 3.7e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KZN87239.1 - 5.9e-05 23.3 0.0 0.00011 22.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KZN87239.1 - 8.1e-05 23.0 0.0 0.00011 22.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fungal_trans PF04082.18 KZN87240.1 - 5.6e-08 32.1 0.0 9.6e-08 31.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN87240.1 - 2.1e-07 30.9 9.4 4.5e-07 29.9 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_MLP1_2 PF07926.12 KZN87241.1 - 0.0061 16.6 1.7 0.0092 16.0 1.7 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Prefoldin_2 PF01920.20 KZN87241.1 - 0.021 14.8 1.4 0.031 14.2 1.4 1.2 1 0 0 1 1 1 0 Prefoldin subunit KASH_CCD PF14662.6 KZN87241.1 - 0.051 13.4 0.4 0.075 12.8 0.4 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH KELK PF15796.5 KZN87241.1 - 0.065 13.7 0.8 0.11 13.0 0.8 1.2 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ZapB PF06005.12 KZN87241.1 - 0.092 13.2 1.5 0.16 12.4 1.5 1.3 1 0 0 1 1 1 0 Cell division protein ZapB APG6_N PF17675.1 KZN87241.1 - 0.15 12.6 0.4 0.24 11.9 0.4 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Dynamin_M PF01031.20 KZN87242.1 - 5.4e-19 68.5 0.0 2e-18 66.6 0.0 1.8 1 1 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KZN87242.1 - 1.8e-11 44.4 0.0 5.5e-11 42.8 0.0 1.9 1 0 0 1 1 1 1 Dynamin family TLD PF07534.16 KZN87243.1 - 8.6e-25 87.6 0.0 1.3e-14 54.6 0.0 2.2 2 0 0 2 2 2 2 TLD JAB PF01398.21 KZN87244.1 - 5.2e-14 52.2 0.0 1.3e-13 50.9 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 KZN87244.1 - 3.4e-10 40.1 1.7 5.7e-10 39.4 1.7 1.3 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 KZN87244.1 - 0.00016 21.4 0.0 0.00045 20.0 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain RrnaAD PF00398.20 KZN87245.1 - 8.4e-06 25.0 0.0 1.7e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Pkinase PF00069.25 KZN87246.1 - 1.4e-12 47.6 0.0 2.9e-12 46.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN87246.1 - 7.1e-05 22.2 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2512 PF10710.9 KZN87246.1 - 0.035 13.8 0.0 2.3 7.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2512) APH PF01636.23 KZN87246.1 - 0.046 13.6 0.0 0.094 12.6 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Peptidase_C13 PF01650.18 KZN87247.1 - 0.006 16.1 0.0 0.0063 16.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase C13 family RT_RNaseH PF17917.1 KZN87248.1 - 5.6e-06 26.6 0.0 7.2e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KZN87248.1 - 0.00045 20.2 0.0 0.00066 19.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Polyketide_cyc2 PF10604.9 KZN87249.1 - 0.00054 20.2 7.8 0.00077 19.8 2.2 2.7 1 1 1 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KZN87249.1 - 0.073 13.3 2.7 0.43 10.8 2.7 2.0 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport DEC-1_N PF04625.13 KZN87249.1 - 0.14 11.1 4.9 0.17 10.9 4.9 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region MSA-2c PF12238.8 KZN87249.1 - 8.6 6.3 8.5 12 5.8 8.5 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Fungal_trans_2 PF11951.8 KZN87251.1 - 3.5e-10 39.2 0.3 4.1e-09 35.7 0.3 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN87251.1 - 0.00022 21.3 7.1 0.00022 21.3 7.1 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.21 KZN87252.1 - 1.7e-97 327.3 0.0 6.9e-97 325.2 0.0 1.7 1 1 0 1 1 1 1 Amidase Iso_dh PF00180.20 KZN87254.1 - 4.8e-70 236.4 0.0 5.7e-70 236.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase FTHFS PF01268.19 KZN87255.1 - 3e-252 837.8 0.1 4.3e-252 837.3 0.1 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KZN87255.1 - 9.8e-67 223.3 0.9 2.4e-66 222.0 0.9 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KZN87255.1 - 8.3e-37 126.0 0.5 1.7e-36 125.0 0.5 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 KZN87255.1 - 0.01 14.8 0.2 0.021 13.8 0.2 1.4 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family GTP_EFTU PF00009.27 KZN87255.1 - 0.035 13.6 0.3 0.081 12.5 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain WD40 PF00400.32 KZN87256.1 - 2.9e-27 94.4 2.5 6.5e-09 36.3 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN87256.1 - 4.2e-12 46.2 0.1 0.0016 18.7 0.2 5.7 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KZN87256.1 - 2.3e-06 27.4 0.2 1e-05 25.2 0.2 2.0 1 1 0 1 1 1 1 PQQ-like domain Gmad1 PF10647.9 KZN87256.1 - 0.00062 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain WD40_like PF17005.5 KZN87256.1 - 0.0014 18.0 0.0 0.01 15.2 0.0 2.4 2 1 0 2 2 2 1 WD40-like domain Nup160 PF11715.8 KZN87256.1 - 0.0021 16.8 0.1 0.003 16.3 0.1 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 MBF1 PF08523.10 KZN87257.1 - 2.5e-23 82.3 0.8 4.6e-23 81.4 0.8 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KZN87257.1 - 1.2e-08 34.8 0.1 2.1e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KZN87257.1 - 0.00041 20.6 0.0 0.001 19.4 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain SH3_1 PF00018.28 KZN87258.1 - 1e-14 53.9 0.0 1.5e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KZN87258.1 - 1.2e-13 50.6 0.1 3.1e-13 49.4 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KZN87258.1 - 3.6e-08 33.0 0.0 5.8e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Ank_2 PF12796.7 KZN87259.1 - 3e-30 104.7 3.3 5e-13 49.5 0.1 4.0 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN87259.1 - 5.3e-25 87.5 1.3 1.6e-07 31.7 0.0 5.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KZN87259.1 - 3.9e-21 74.8 3.1 2.5e-06 27.6 0.0 5.2 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KZN87259.1 - 9.6e-18 63.8 6.8 5e-05 23.5 0.0 7.0 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.6 KZN87259.1 - 8.8e-16 56.4 6.4 0.028 14.9 0.0 7.8 8 0 0 8 8 8 4 Ankyrin repeat AIM24 PF01987.17 KZN87260.1 - 1.9e-53 181.3 0.0 2.4e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 eIF-5_eIF-2B PF01873.17 KZN87261.1 - 7.2e-40 135.5 0.3 1.2e-39 134.8 0.3 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 KZN87261.1 - 0.2 11.2 1.3 0.42 10.2 1.3 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Arc_trans_TRASH PF08394.10 KZN87261.1 - 2 8.8 7.6 1.3 9.4 0.4 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain RRM_1 PF00076.22 KZN87264.1 - 1.2e-18 66.6 0.0 1.8e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ChaC PF04752.12 KZN87265.1 - 2.2e-40 138.6 0.2 2.8e-39 135.0 0.2 2.0 1 1 0 1 1 1 1 ChaC-like protein DUF3433 PF11915.8 KZN87266.1 - 3.3e-39 133.2 8.2 4.1e-22 78.4 0.4 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) adh_short PF00106.25 KZN87267.1 - 1.1e-17 64.2 0.0 3.4e-16 59.3 0.0 2.5 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN87267.1 - 7e-11 42.1 0.0 2.3e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN87267.1 - 1.2e-06 28.6 0.0 2.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Ank_2 PF12796.7 KZN87268.1 - 4.5e-56 187.4 6.1 4.8e-11 43.1 0.0 6.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN87268.1 - 1.5e-42 143.4 2.0 4.4e-07 30.3 0.0 9.4 4 3 6 10 10 9 9 Ankyrin repeats (many copies) Ank PF00023.30 KZN87268.1 - 1.1e-31 107.9 5.1 0.032 14.7 0.0 10.9 10 0 0 10 10 10 8 Ankyrin repeat Ank_3 PF13606.6 KZN87268.1 - 8.6e-25 84.1 1.2 0.4 11.4 0.0 11.5 11 0 0 11 11 11 5 Ankyrin repeat Ank_5 PF13857.6 KZN87268.1 - 6.4e-22 77.3 10.9 4.8e-05 23.6 0.1 6.5 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Helo_like_N PF17111.5 KZN87268.1 - 1.1e-10 41.2 0.1 2.8e-10 39.9 0.1 1.8 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins NACHT PF05729.12 KZN87268.1 - 6.3e-07 29.5 0.0 1.6e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KZN87268.1 - 0.027 14.7 0.2 0.17 12.2 0.0 2.4 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 KZN87268.1 - 0.096 11.8 0.2 0.69 9.1 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain eIF-5a PF01287.20 KZN87268.1 - 0.17 12.0 1.5 54 4.0 0.0 4.7 4 1 1 5 5 5 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Apolipoprotein PF01442.18 KZN87268.1 - 2.1 8.2 5.8 0.9 9.4 0.9 2.7 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain EF-hand_1 PF00036.32 KZN87269.1 - 3.7e-21 73.0 0.2 7.8e-08 31.3 0.1 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KZN87269.1 - 2.7e-19 67.4 0.5 0.0001 21.9 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 KZN87269.1 - 1.9e-18 66.7 0.0 1.1e-08 35.4 0.0 3.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 KZN87269.1 - 1.6e-17 63.1 0.1 2.1e-08 33.9 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KZN87269.1 - 8.5e-15 53.5 0.8 0.00027 20.3 0.0 3.6 4 0 0 4 4 4 3 EF hand F-box-like PF12937.7 KZN87270.1 - 0.00078 19.3 6.7 0.01 15.7 6.0 2.9 2 1 0 2 2 2 1 F-box-like Cytokin_check_N PF10407.9 KZN87270.1 - 0.0074 16.2 0.0 0.0074 16.2 0.0 1.9 2 0 0 2 2 2 1 Cdc14 phosphatase binding protein N-terminus MFS_1 PF07690.16 KZN87272.1 - 4.9e-50 170.4 59.7 2.9e-48 164.6 59.7 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KZN87272.1 - 2.1e-22 79.3 18.7 3.3e-22 78.6 18.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KZN87272.1 - 1.9e-12 46.8 14.7 1.9e-12 46.8 14.7 3.0 1 1 1 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.6 KZN87272.1 - 0.00012 20.8 4.2 0.00012 20.8 4.2 3.7 4 0 0 4 4 4 2 MFS/sugar transport protein OATP PF03137.20 KZN87272.1 - 0.0029 16.0 2.4 0.0029 16.0 2.4 3.8 3 1 1 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family zf-C2H2 PF00096.26 KZN87274.1 - 0.00038 20.8 12.3 0.0094 16.4 0.6 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KZN87274.1 - 0.00073 20.2 4.6 0.25 12.3 0.4 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 KZN87274.1 - 0.012 15.9 1.7 0.012 15.9 1.7 2.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zap1_zf2 PF18217.1 KZN87274.1 - 0.055 13.5 1.6 0.055 13.5 1.6 2.0 2 0 0 2 2 2 0 Zap1 zinc finger 2 FOXP-CC PF16159.5 KZN87274.1 - 0.13 12.9 1.1 0.31 11.7 0.1 2.0 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 KZN87274.1 - 0.26 11.8 3.0 0.29 11.7 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 KZN87274.1 - 0.27 11.3 0.3 0.27 11.3 0.3 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-AN1 PF01428.16 KZN87274.1 - 0.6 10.3 4.0 0.28 11.4 0.5 2.1 2 0 0 2 2 2 0 AN1-like Zinc finger MoCF_biosynth PF00994.24 KZN87275.1 - 5.6e-21 74.7 0.0 8e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_N PF03453.17 KZN87275.1 - 1.7e-13 50.6 0.0 2.5e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) B12-binding PF02310.19 KZN87275.1 - 0.009 16.0 0.0 0.018 15.1 0.0 1.5 2 0 0 2 2 2 1 B12 binding domain NTP_transf_3 PF12804.7 KZN87276.1 - 6.4e-19 68.9 0.1 1e-18 68.2 0.1 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain Molybdopterin PF00384.22 KZN87277.1 - 1e-65 222.4 0.0 1.5e-65 221.9 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 KZN87277.1 - 2e-29 101.9 0.0 5.4e-29 100.5 0.0 1.8 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 KZN87277.1 - 5.4e-13 48.7 0.8 2.4e-12 46.6 0.5 2.3 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Fe4S4 domain ArAE_1_C PF11728.8 KZN87277.1 - 0.24 11.4 0.0 0.54 10.2 0.0 1.5 1 0 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain zf-C2H2 PF00096.26 KZN87278.1 - 1.3e-06 28.6 8.2 0.0025 18.2 1.5 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KZN87278.1 - 0.0067 16.2 13.4 0.029 14.1 1.9 3.0 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KZN87278.1 - 0.017 15.9 8.7 1.1 10.3 1.8 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 KZN87278.1 - 0.028 14.7 2.2 0.06 13.7 0.3 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 KZN87278.1 - 0.063 13.7 0.9 0.063 13.7 0.9 2.4 3 0 0 3 3 3 0 Zinc-finger double domain G6PD_C PF02781.16 KZN87279.1 - 3.8e-116 387.3 0.0 6.4e-116 386.6 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KZN87279.1 - 7.6e-62 209.1 0.1 1.3e-61 208.3 0.1 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF3226 PF11536.8 KZN87279.1 - 0.073 12.7 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) MFS_2 PF13347.6 KZN87280.1 - 1.8e-10 40.0 10.8 1.8e-10 40.0 10.8 2.2 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.7 KZN87280.1 - 0.00013 20.9 0.0 0.00033 19.6 0.0 1.8 1 1 0 1 1 1 1 MFS_1 like family DUF2976 PF11190.8 KZN87280.1 - 0.087 12.6 0.4 9.1 6.2 0.1 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF2976) DJ-1_PfpI PF01965.24 KZN87282.1 - 2.2e-10 40.6 0.0 4.7e-10 39.5 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KZN87282.1 - 3.3e-05 23.7 0.0 0.00014 21.6 0.0 1.9 1 1 0 1 1 1 1 ThiJ/PfpI family-like Bacteriocin_IIc PF10439.9 KZN87282.1 - 0.055 13.6 2.9 0.13 12.3 2.9 1.6 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF1708 PF08101.11 KZN87283.1 - 1.1e-173 578.3 0.0 1.7e-173 577.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) RhoGAP PF00620.27 KZN87283.1 - 0.014 15.2 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 RhoGAP domain SRF-TF PF00319.18 KZN87284.1 - 1.2e-23 82.3 0.2 1.8e-23 81.7 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) GFA PF04828.14 KZN87285.1 - 1.1e-24 86.6 0.1 1.4e-24 86.3 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme SIMPL PF04402.14 KZN87286.1 - 2.2e-21 77.2 0.0 2.5e-21 77.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Aminotran_1_2 PF00155.21 KZN87287.1 - 2.4e-41 142.1 0.0 2.8e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 KZN87287.1 - 0.062 12.0 0.0 0.091 11.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III Ank_2 PF12796.7 KZN87288.1 - 2.1e-44 150.0 7.0 4.7e-13 49.5 0.1 5.6 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KZN87288.1 - 7.8e-33 108.8 4.4 8.1e-05 22.7 0.0 10.4 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 KZN87288.1 - 2.9e-31 107.1 7.1 9.3e-06 25.8 0.2 8.9 3 2 6 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 KZN87288.1 - 3.7e-31 106.2 9.3 0.00013 22.2 0.0 10.7 11 0 0 11 11 11 7 Ankyrin repeat Ank_4 PF13637.6 KZN87288.1 - 3.6e-28 97.6 1.8 4.4e-07 30.3 0.2 7.6 3 2 4 7 7 7 6 Ankyrin repeats (many copies) NACHT_N PF17100.5 KZN87288.1 - 5.8e-24 85.2 2.5 9.9e-24 84.4 1.6 1.9 2 0 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 KZN87288.1 - 0.0045 16.9 0.0 0.015 15.2 0.0 1.9 1 0 0 1 1 1 1 NACHT domain Viral_helicase1 PF01443.18 KZN87288.1 - 0.032 13.9 0.1 3.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Retinal PF15449.6 KZN87288.1 - 3 5.5 8.2 4.1 5.1 8.2 1.1 1 0 0 1 1 1 0 Retinal protein PAPS_reduct PF01507.19 KZN87289.1 - 1.5e-42 145.6 0.2 3.3e-42 144.5 0.0 1.6 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family HAD PF12710.7 KZN87290.1 - 2.8e-22 80.0 0.0 4e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KZN87290.1 - 1.1e-17 65.0 0.4 1.6e-17 64.5 0.4 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KZN87290.1 - 3.4e-10 40.1 0.1 1.1e-08 35.2 0.0 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KZN87290.1 - 8.5e-07 29.2 0.0 1e-05 25.7 0.0 2.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KZN87290.1 - 0.001 18.5 0.0 0.025 14.0 0.0 2.1 2 0 0 2 2 2 1 Putative Phosphatase DUF705 PF05152.12 KZN87290.1 - 0.15 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) LIAS_N PF16881.5 KZN87291.1 - 2.9e-26 92.0 0.0 5.7e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KZN87291.1 - 1.1e-14 55.2 0.0 1.8e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily WD40 PF00400.32 KZN87293.1 - 7.4e-09 36.1 8.7 0.00015 22.5 0.2 5.0 5 1 0 5 5 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN87293.1 - 0.00013 22.2 0.0 18 5.7 0.0 4.3 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KZN87293.1 - 0.00043 19.9 1.0 0.0016 18.1 0.3 2.3 2 1 0 2 2 2 1 PQQ-like domain PQQ_3 PF13570.6 KZN87293.1 - 0.091 13.3 4.2 6.6 7.4 0.1 3.9 3 1 0 3 3 3 0 PQQ-like domain FAM76 PF16046.5 KZN87293.1 - 0.1 12.0 3.7 0.14 11.5 3.7 1.2 1 0 0 1 1 1 0 FAM76 protein WD40_alt PF14077.6 KZN87293.1 - 0.16 11.9 0.3 0.43 10.5 0.3 1.7 1 0 0 1 1 1 0 Alternative WD40 repeat motif TMF_TATA_bd PF12325.8 KZN87293.1 - 0.21 11.8 8.3 0.49 10.6 8.2 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding SKA1 PF07160.12 KZN87293.1 - 0.45 10.3 6.3 0.73 9.6 6.3 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF4140 PF13600.6 KZN87293.1 - 2.2 8.8 10.6 58 4.2 10.3 2.7 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) APG6_N PF17675.1 KZN87293.1 - 7.3 7.1 12.8 11 6.5 12.8 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Cep57_CLD_2 PF14197.6 KZN87293.1 - 7.3 6.8 11.4 13 5.9 11.4 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 SelK_SelG PF10961.8 KZN87294.1 - 2.1e-07 31.4 18.5 1.3e-06 28.9 18.5 2.0 1 1 0 1 1 1 1 Selenoprotein SelK_SelG GRP PF07172.11 KZN87294.1 - 0.00027 21.6 1.5 0.00033 21.3 1.5 1.1 1 0 0 1 1 1 1 Glycine rich protein family TP_methylase PF00590.20 KZN87295.1 - 4.7e-48 163.9 0.0 8e-48 163.2 0.0 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 KZN87295.1 - 4.8e-15 55.9 0.0 9.7e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KZN87295.1 - 2.5e-11 43.0 0.0 2.4e-07 30.3 0.0 2.6 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KZN87295.1 - 5.4e-08 32.1 0.1 1.6e-07 30.6 0.1 1.9 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central DUF498 PF04430.14 KZN87295.1 - 0.036 14.1 0.0 0.77 9.8 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) preATP-grasp_3 PF18301.1 KZN87295.1 - 0.13 12.6 0.0 0.45 10.8 0.0 1.9 1 0 0 1 1 1 0 pre ATP-grasp 3 domain PCI PF01399.27 KZN87296.1 - 3.8e-22 78.8 0.0 1.2e-21 77.1 0.0 2.0 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 KZN87296.1 - 1.1e-15 57.4 2.0 2.9e-15 56.1 2.0 1.8 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain ERp29 PF07749.12 KZN87296.1 - 7.6 7.5 8.3 2.3 9.2 0.1 3.4 3 0 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain FSH1 PF03959.13 KZN87297.1 - 1.5e-72 243.7 0.0 1.9e-72 243.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KZN87297.1 - 1.4e-06 29.0 1.5 3.4e-06 27.8 1.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KZN87297.1 - 0.0053 16.6 0.1 4.5 7.0 0.1 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase DLH PF01738.18 KZN87297.1 - 0.036 13.6 0.1 1.8 8.0 0.0 2.2 1 1 1 2 2 2 0 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KZN87297.1 - 0.088 12.1 0.3 0.33 10.2 0.0 2.0 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 KZN87297.1 - 0.12 12.5 0.0 0.29 11.2 0.1 1.6 2 0 0 2 2 2 0 Thioesterase domain Ribosomal_S27e PF01667.17 KZN87299.1 - 9.9e-29 98.8 6.7 1.3e-28 98.5 6.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-C2HC5 PF06221.13 KZN87299.1 - 0.29 11.2 6.3 2 8.4 4.2 2.3 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type CDP-OH_P_transf PF01066.21 KZN87300.1 - 4.4e-11 43.4 0.0 4.4e-11 43.4 0.0 3.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Peptidase_U4 PF03419.13 KZN87300.1 - 0.019 14.3 4.4 0.035 13.4 4.4 1.4 1 0 0 1 1 1 0 Sporulation factor SpoIIGA NIPSNAP PF07978.13 KZN87301.1 - 1.1e-40 137.9 5.7 1.5e-28 99.0 0.1 2.8 3 0 0 3 3 3 2 NIPSNAP Putative_PNPOx PF01243.20 KZN87302.1 - 2.3e-12 46.9 0.0 6.1e-12 45.6 0.0 1.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 KZN87302.1 - 0.015 15.3 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase BPL_LplA_LipB PF03099.19 KZN87303.1 - 2.7e-06 27.3 0.0 5.1e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Ras PF00071.22 KZN87304.1 - 7.1e-19 68.0 0.0 8.2e-19 67.8 0.0 1.0 1 0 0 1 1 1 1 Ras family PCI PF01399.27 KZN87305.1 - 1.4e-19 70.6 0.1 3.5e-19 69.3 0.1 1.7 1 0 0 1 1 1 1 PCI domain Peptidase_C65 PF10275.9 KZN87306.1 - 3.7e-57 193.6 0.0 4.6e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain DJ-1_PfpI PF01965.24 KZN87307.1 - 4.9e-15 55.7 0.0 6.1e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 KZN87307.1 - 0.25 11.1 0.0 0.34 10.7 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Sugar_tr PF00083.24 KZN87308.1 - 1.6e-120 403.0 15.2 2.5e-120 402.4 15.2 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN87308.1 - 2.2e-23 82.7 60.4 6.2e-18 64.8 31.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KZN87308.1 - 0.00016 20.3 1.8 0.00016 20.3 1.8 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.18 KZN87309.1 - 1.5e-27 96.3 0.0 2.7e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN87309.1 - 3.6e-10 39.8 10.8 6.1e-10 39.1 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 KZN87309.1 - 2.3e-05 24.5 0.1 4.6e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Gal4-like dimerisation domain ELP6 PF09807.9 KZN87310.1 - 2.4e-16 59.9 0.0 6e-07 29.1 0.0 2.1 2 0 0 2 2 2 2 Elongation complex protein 6 ATPase PF06745.13 KZN87310.1 - 0.025 14.0 0.0 0.058 12.7 0.0 1.6 1 0 0 1 1 1 0 KaiC Elong_Iki1 PF10483.9 KZN87310.1 - 0.087 12.3 0.0 0.75 9.2 0.0 1.9 2 0 0 2 2 2 0 Elongator subunit Iki1 Slu7 PF11708.8 KZN87311.1 - 1.7e-80 270.6 13.0 1.7e-80 270.6 13.0 2.3 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 KZN87311.1 - 0.035 13.8 0.6 0.073 12.8 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle DNA_pol_B PF00136.21 KZN87312.1 - 1.2e-103 347.3 0.0 1.6e-103 346.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KZN87312.1 - 3.8e-23 82.2 0.0 3.1e-13 49.6 0.0 2.6 2 1 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KZN87312.1 - 3.6e-18 65.8 2.2 3.6e-18 65.8 2.2 2.2 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta Glyco_transf_4 PF13439.6 KZN87312.1 - 0.048 13.7 0.8 1.6 8.7 0.1 2.9 2 1 0 2 2 2 0 Glycosyltransferase Family 4 DNA_pol_B_2 PF03175.13 KZN87312.1 - 0.13 11.1 0.1 0.22 10.4 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral RdRP PF05183.12 KZN87313.1 - 9.4e-184 612.3 0.0 2.6e-183 610.9 0.0 1.7 2 0 0 2 2 2 1 RNA dependent RNA polymerase RRM_1 PF00076.22 KZN87313.1 - 0.00035 20.4 0.0 0.0012 18.6 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD-oxidase_C PF02913.19 KZN87315.1 - 6e-63 212.8 0.0 7.8e-63 212.4 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KZN87315.1 - 4.9e-36 123.5 0.0 1e-35 122.5 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain SepSecS PF05889.13 KZN87315.1 - 0.1 11.2 0.0 0.19 10.4 0.0 1.3 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Semialdhyde_dhC PF02774.18 KZN87316.1 - 8.7e-35 120.5 0.0 1.4e-34 119.8 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KZN87316.1 - 5e-30 104.4 0.0 1.3e-29 103.1 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KZN87316.1 - 0.03 14.6 0.0 0.19 12.0 0.0 2.2 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Ribosomal_S4e PF00900.20 KZN87317.1 - 2.1e-38 130.1 0.2 4.1e-38 129.1 0.2 1.5 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 KZN87317.1 - 1.2e-24 85.7 0.0 2e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KZN87317.1 - 8.5e-17 61.0 5.8 1.6e-16 60.1 5.8 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 KZN87317.1 - 3e-07 30.1 0.0 5.5e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KZN87317.1 - 0.0029 17.5 1.9 0.0029 17.5 1.9 2.9 3 0 0 3 3 3 1 KOW motif RasGEF PF00617.19 KZN87318.1 - 5.8e-07 29.9 0.0 1.8e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 RasGEF domain Cdc6_C PF09079.11 KZN87318.1 - 0.085 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Myb_DNA-bind_6 PF13921.6 KZN87320.1 - 4e-16 59.0 0.0 5.8e-08 32.9 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KZN87320.1 - 3.2e-15 56.0 0.4 3.2e-08 33.6 0.1 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 KZN87320.1 - 0.00098 19.1 0.0 0.7 9.9 0.0 2.4 2 0 0 2 2 2 2 SLIDE PX PF00787.24 KZN87321.1 - 1.2e-27 96.1 0.2 1.5e-27 95.8 0.2 1.1 1 0 0 1 1 1 1 PX domain GFA PF04828.14 KZN87322.1 - 1.1e-11 44.8 5.5 7.5e-09 35.8 0.0 2.5 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 KZN87322.1 - 3.6 7.8 6.6 16 5.7 0.3 2.4 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like WD40 PF00400.32 KZN87323.1 - 6.3e-18 64.8 18.1 0.00066 20.4 0.2 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 KZN87323.1 - 6.6e-05 21.6 2.3 0.32 9.5 0.0 4.1 3 1 2 5 5 5 3 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 KZN87323.1 - 0.052 13.8 0.0 1.9 8.8 0.0 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PPARgamma_N PF12577.8 KZN87323.1 - 0.073 13.7 3.6 15 6.3 1.1 3.1 2 1 0 2 2 2 0 PPAR gamma N-terminal region PQQ_3 PF13570.6 KZN87323.1 - 0.093 13.3 1.8 5.3 7.7 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain SecE PF00584.20 KZN87324.1 - 4.7e-15 55.2 0.0 5.5e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex RRM_1 PF00076.22 KZN87325.1 - 2.9e-05 23.8 0.0 5.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AXE1 PF05448.12 KZN87327.1 - 0.00016 20.4 0.0 0.25 10.0 0.0 2.8 2 1 0 3 3 3 2 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 KZN87327.1 - 0.00046 19.5 0.0 0.37 10.0 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KZN87327.1 - 0.033 14.8 0.0 0.22 12.1 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family Mito_carr PF00153.27 KZN87330.1 - 2.8e-73 241.9 2.7 8.9e-25 86.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KZN87330.1 - 0.068 12.3 1.2 1.2 8.2 0.0 3.0 3 1 0 3 3 3 0 Gammaproteobacterial serine protease Ribosomal_L21e PF01157.18 KZN87331.1 - 1.5e-46 156.4 4.7 1.5e-46 156.4 4.7 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e CEP1-DNA_bind PF09287.10 KZN87331.1 - 0.063 12.9 0.2 0.073 12.7 0.2 1.2 1 0 0 1 1 1 0 CEP-1, DNA binding S4 PF01479.25 KZN87332.1 - 2e-12 46.6 0.5 2e-12 46.6 0.5 2.3 3 0 0 3 3 3 1 S4 domain Baculo_PEP_C PF04513.12 KZN87333.1 - 0.047 13.7 1.2 0.49 10.4 0.5 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 KZN87333.1 - 0.22 11.8 1.3 0.39 11.0 0.5 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 KZN87333.1 - 0.35 11.2 3.8 0.64 10.4 2.3 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Usp PF00582.26 KZN87333.1 - 0.53 10.8 4.8 8.7 6.9 0.1 2.6 2 1 0 2 2 2 0 Universal stress protein family ABC_tran_CTD PF16326.5 KZN87333.1 - 0.56 10.5 17.4 0.12 12.6 3.2 4.4 1 1 4 5 5 5 0 ABC transporter C-terminal domain Prefoldin PF02996.17 KZN87333.1 - 0.69 9.8 8.0 0.28 11.1 1.1 3.1 2 2 1 3 3 3 0 Prefoldin subunit YabA PF06156.13 KZN87333.1 - 1.3 9.7 8.7 4.2 8.1 0.3 3.1 2 1 0 2 2 2 0 Initiation control protein YabA T3SSipB PF16535.5 KZN87333.1 - 1.3 9.4 10.4 5.2 7.5 10.5 1.9 1 1 0 1 1 1 0 Type III cell invasion protein SipB GAS PF13851.6 KZN87333.1 - 1.5 8.2 10.4 5.2 6.4 1.2 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 KZN87333.1 - 1.6 9.2 14.6 11 6.5 14.6 2.0 1 1 0 1 1 1 0 Fez1 OmpH PF03938.14 KZN87333.1 - 2.5 8.5 15.0 1 9.7 1.3 2.6 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) DUF1664 PF07889.12 KZN87333.1 - 4 7.5 5.3 1.3 9.1 2.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FmiP_Thoc5 PF09766.9 KZN87333.1 - 4.2 6.6 10.1 9.6 5.4 10.2 1.5 1 1 0 1 1 1 0 Fms-interacting protein/Thoc5 Jnk-SapK_ap_N PF09744.9 KZN87333.1 - 4.9 7.4 13.4 0.56 10.4 2.6 2.4 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Prefoldin_2 PF01920.20 KZN87333.1 - 5.8 6.9 10.7 1.2 9.1 1.7 3.4 2 2 1 3 3 3 0 Prefoldin subunit HIP1_clath_bdg PF16515.5 KZN87333.1 - 7.5 7.2 17.2 0.19 12.3 4.4 2.8 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TMPIT PF07851.13 KZN87333.1 - 7.8 5.6 5.8 2.1 7.5 1.1 2.2 3 0 0 3 3 3 0 TMPIT-like protein Uso1_p115_C PF04871.13 KZN87333.1 - 8.4 6.8 17.3 11 6.5 2.8 2.6 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region PRKG1_interact PF15898.5 KZN87333.1 - 8.4 7.4 15.0 8.2 7.4 1.9 3.0 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain DOPA_dioxygen PF08883.11 KZN87335.1 - 9.5e-42 141.5 0.0 1.2e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Vps62 PF06101.11 KZN87336.1 - 1.4e-07 30.3 0.5 0.00022 19.7 0.1 2.3 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 62 Septin PF00735.18 KZN87337.1 - 6.8e-35 120.7 0.0 6.9e-14 51.8 0.0 3.1 3 0 0 3 3 3 3 Septin MMR_HSR1 PF01926.23 KZN87337.1 - 0.00015 21.8 0.0 0.00042 20.4 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KZN87337.1 - 0.009 15.4 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Dynamin_N PF00350.23 KZN87337.1 - 0.039 14.0 0.4 0.18 11.9 0.0 2.3 2 1 0 2 2 2 0 Dynamin family G-alpha PF00503.20 KZN87337.1 - 0.054 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit AAA_16 PF13191.6 KZN87337.1 - 0.068 13.5 0.0 0.19 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 KZN87337.1 - 0.12 12.8 0.8 0.33 11.4 0.8 1.9 1 1 0 1 1 1 0 AAA domain Annexin PF00191.20 KZN87338.1 - 9.7e-16 57.6 3.5 3e-06 27.2 0.0 4.4 4 0 0 4 4 4 4 Annexin DUF4910 PF16254.5 KZN87339.1 - 0.052 12.4 0.0 0.088 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4910) DUF5127 PF17168.4 KZN87340.1 - 5.6e-85 284.7 7.6 8.2e-85 284.2 7.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KZN87340.1 - 2.4e-79 265.0 0.5 2.4e-79 265.0 0.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KZN87340.1 - 5.6e-67 225.3 0.2 5.6e-67 225.3 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KZN87340.1 - 1.9e-06 27.3 1.5 8.9e-06 25.2 1.5 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4964) Peptidase_M20 PF01546.28 KZN87341.1 - 6.3e-29 101.2 0.0 1.9e-28 99.6 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KZN87341.1 - 8.1e-11 41.8 0.0 2.5e-10 40.2 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KZN87341.1 - 0.048 13.3 0.0 0.097 12.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 WSC PF01822.19 KZN87342.1 - 1.1e-15 57.6 11.1 2e-15 56.7 11.1 1.5 1 0 0 1 1 1 1 WSC domain GRDP-like PF07173.12 KZN87343.1 - 4e-16 60.0 0.0 3.2e-13 50.5 0.0 2.7 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like MARVEL PF01284.23 KZN87344.1 - 0.00029 20.9 12.5 0.00038 20.5 12.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF2070 PF09843.9 KZN87344.1 - 0.13 10.6 8.8 0.14 10.4 8.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4191 PF13829.6 KZN87344.1 - 0.76 9.1 4.6 0.14 11.5 0.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) TMEM208_SND2 PF05620.11 KZN87344.1 - 8.6 6.1 10.7 0.38 10.5 3.0 2.0 1 1 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 AMP-binding PF00501.28 KZN87345.1 - 6.2e-69 232.6 0.0 8.1e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KZN87345.1 - 2.2e-55 187.6 0.0 3.9e-55 186.8 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KZN87345.1 - 6.6e-10 38.9 0.0 2e-09 37.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KZN87345.1 - 1.5e-09 38.1 0.0 2.9e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KZN87345.1 - 4.1e-06 26.0 0.0 1.2e-05 24.4 0.0 1.8 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 KZN87345.1 - 1e-05 26.4 0.0 2.9e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.15 KZN87345.1 - 0.0056 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein WD40 PF00400.32 KZN87346.1 - 4e-41 138.2 23.8 9e-06 26.3 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN87346.1 - 2.9e-06 27.5 2.2 0.85 10.0 0.1 5.0 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KZN87346.1 - 4e-06 26.8 0.0 5.9 7.0 0.0 4.9 2 1 2 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 KZN87346.1 - 6.9e-05 21.7 8.4 0.14 10.8 0.3 4.3 2 2 2 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KZN87346.1 - 0.00012 21.0 1.9 0.78 8.4 0.0 4.3 2 2 1 4 4 4 2 Nup133 N terminal like WD40_like PF17005.5 KZN87346.1 - 0.0024 17.2 0.0 1.2 8.4 0.0 2.4 2 0 0 2 2 2 2 WD40-like domain PQQ_2 PF13360.6 KZN87346.1 - 0.041 13.5 0.9 4.2 6.9 0.1 2.7 1 1 1 3 3 3 0 PQQ-like domain PALB2_WD40 PF16756.5 KZN87346.1 - 0.058 12.3 2.1 14 4.5 0.1 3.9 2 2 2 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Myb_DNA-binding PF00249.31 KZN87348.1 - 2.4e-06 27.6 0.0 4.7e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KZN87348.1 - 0.001 19.2 0.0 0.0031 17.7 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KZN87348.1 - 0.094 12.6 0.1 3.2 7.7 0.0 2.5 2 0 0 2 2 2 0 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 KZN87348.1 - 0.17 12.3 4.3 0.6 10.5 1.9 2.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain UPF0016 PF01169.19 KZN87349.1 - 3.1e-41 139.6 25.6 4.9e-21 74.8 10.3 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Presenilin PF01080.17 KZN87349.1 - 0.081 11.7 0.4 0.15 10.8 0.4 1.4 1 0 0 1 1 1 0 Presenilin DUF3357 PF11837.8 KZN87349.1 - 0.095 13.2 1.6 12 6.5 0.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) MFS_1 PF07690.16 KZN87350.1 - 8.8e-36 123.5 25.6 8.8e-36 123.5 25.6 2.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN87350.1 - 4e-15 55.6 3.3 4e-15 55.6 3.3 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KZN87350.1 - 0.0051 15.3 4.7 0.0083 14.6 4.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FAA_hydrolase PF01557.18 KZN87351.1 - 3.3e-49 167.5 0.0 4.7e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Cupin_2 PF07883.11 KZN87352.1 - 8.6e-27 92.7 0.7 3.6e-16 58.6 0.1 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 KZN87352.1 - 7.4e-06 25.9 3.6 0.0047 16.8 0.5 2.5 1 1 1 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.12 KZN87352.1 - 0.00035 20.2 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) CENP-C_C PF11699.8 KZN87352.1 - 0.003 17.7 0.0 0.046 13.9 0.0 2.1 2 0 0 2 2 2 1 Mif2/CENP-C like ARD PF03079.14 KZN87352.1 - 0.0086 16.3 0.1 0.19 11.9 0.0 2.2 2 0 0 2 2 2 1 ARD/ARD' family Fungal_trans PF04082.18 KZN87353.1 - 2.4e-25 89.1 0.0 5.3e-25 87.9 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN87353.1 - 1.2e-09 38.1 6.3 2.6e-09 37.1 6.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DASH_Duo1 PF08651.10 KZN87353.1 - 0.12 12.1 0.1 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 DASH complex subunit Duo1 ADH_zinc_N PF00107.26 KZN87354.1 - 6.6e-23 81.1 0.1 1.1e-22 80.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KZN87354.1 - 1.7e-21 76.1 2.6 3.3e-21 75.2 2.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KZN87354.1 - 7.5e-10 40.0 0.0 1.3e-09 39.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Aldedh PF00171.22 KZN87355.1 - 6.3e-128 427.2 0.0 7e-128 427.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SnoaL_2 PF12680.7 KZN87356.1 - 1e-08 35.7 0.1 1.3e-08 35.4 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain adh_short_C2 PF13561.6 KZN87357.1 - 4.2e-49 167.2 0.0 5.3e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN87357.1 - 1.8e-36 125.5 0.0 2.2e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN87357.1 - 3.3e-08 33.6 0.0 8.5e-08 32.3 0.0 1.7 1 1 0 1 1 1 1 KR domain HATPase_c PF02518.26 KZN87357.1 - 0.012 16.2 0.0 0.023 15.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 3Beta_HSD PF01073.19 KZN87357.1 - 0.037 13.0 0.1 0.059 12.4 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.16 KZN87358.1 - 8.3e-24 84.2 25.1 8.3e-24 84.2 25.1 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN87358.1 - 0.0019 17.1 29.9 0.2 10.5 30.1 2.9 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 KZN87358.1 - 0.0023 16.3 9.6 0.21 9.8 3.3 2.6 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Phage_holin_7_1 PF16081.5 KZN87358.1 - 0.043 14.0 9.0 0.13 12.5 0.6 2.9 2 1 1 3 3 3 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family HATPase_c PF02518.26 KZN87359.1 - 5e-21 75.3 0.0 8.6e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KZN87359.1 - 7.8e-20 71.1 1.0 1.2e-19 70.5 0.1 1.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KZN87359.1 - 2.4e-13 49.9 0.0 7.7e-13 48.3 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Amidohydro_2 PF04909.14 KZN87360.1 - 2.4e-11 43.9 0.0 5e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Aldedh PF00171.22 KZN87361.1 - 2e-152 507.9 0.2 2.3e-152 507.8 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ADH_zinc_N PF00107.26 KZN87362.1 - 5.4e-25 87.9 0.2 8.7e-25 87.2 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KZN87362.1 - 2.4e-15 57.8 0.1 5.8e-15 56.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KZN87362.1 - 1.3e-09 37.8 0.6 6.8e-09 35.6 0.0 2.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain PALP PF00291.25 KZN87362.1 - 0.013 15.0 0.6 0.022 14.2 0.6 1.4 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DUF1338 PF07063.13 KZN87363.1 - 2e-108 362.4 0.0 2.3e-108 362.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) DUF3890 PF13029.6 KZN87363.1 - 0.13 12.8 0.1 2.7 8.5 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3890) Zn_clus PF00172.18 KZN87364.1 - 2.8e-10 40.2 9.7 2.8e-10 40.2 9.7 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN87364.1 - 7.4e-09 35.0 0.1 1.3e-08 34.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 KZN87364.1 - 0.0089 14.9 2.1 0.03 13.1 0.0 2.4 3 0 0 3 3 3 1 Fungal specific transcription factor domain Rep_fac-A_C PF08646.10 KZN87364.1 - 1.2 8.8 5.2 2.2 8.0 5.2 1.4 1 0 0 1 1 1 0 Replication factor-A C terminal domain Amidohydro_2 PF04909.14 KZN87365.1 - 4.1e-52 177.8 0.0 4.9e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Aldedh PF00171.22 KZN87366.1 - 1e-141 472.6 0.0 1.2e-141 472.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ribonuc_L-PSP PF01042.21 KZN87367.1 - 1.3e-18 67.2 0.1 2.5e-18 66.2 0.1 1.5 1 1 0 1 1 1 1 Endoribonuclease L-PSP Sulfatase PF00884.23 KZN87368.1 - 3.5e-78 263.1 0.0 4.5e-78 262.8 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 KZN87368.1 - 0.003 16.3 0.0 0.0044 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4976 PF16347.5 KZN87368.1 - 0.022 15.0 0.0 0.084 13.1 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 KZN87368.1 - 0.065 12.8 0.5 0.18 11.4 0.5 1.9 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 KZN87368.1 - 0.1 13.4 0.9 3.6 8.3 0.5 2.6 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase AA_permease PF00324.21 KZN87369.1 - 2.5e-85 286.9 30.9 2.8e-85 286.7 30.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KZN87369.1 - 3.6e-25 88.7 32.1 4.3e-25 88.4 32.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN87370.1 - 3.1e-21 75.5 11.4 3.6e-21 75.3 11.4 1.0 1 0 0 1 1 1 1 Amino acid permease LapA_dom PF06305.11 KZN87370.1 - 9 6.2 7.1 7.6 6.4 0.1 2.5 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain 7TMR-DISM_7TM PF07695.11 KZN87371.1 - 0.0069 16.3 13.9 0.015 15.2 6.8 2.2 2 0 0 2 2 2 2 7TM diverse intracellular signalling FAD_binding_4 PF01565.23 KZN87372.1 - 1e-18 67.4 3.6 1.9e-18 66.5 3.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KZN87372.1 - 1.6e-10 40.9 0.2 4.4e-10 39.5 0.1 1.9 2 0 0 2 2 2 1 Berberine and berberine like NAD_binding_4 PF07993.12 KZN87373.1 - 3.3e-38 131.3 0.0 5e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KZN87373.1 - 6.4e-28 97.5 0.0 1.7e-27 96.1 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 KZN87373.1 - 2e-15 56.9 0.0 3.8e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KZN87373.1 - 3.2e-07 30.1 0.0 1.6e-06 27.7 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase PP-binding PF00550.25 KZN87373.1 - 0.00021 21.6 0.1 0.00046 20.5 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KZN87373.1 - 0.00036 19.6 0.0 0.00086 18.4 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KZN87373.1 - 0.014 14.5 0.0 0.2 10.7 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_10 PF13460.6 KZN87373.1 - 0.053 13.4 0.0 0.12 12.3 0.0 1.7 1 1 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 KZN87373.1 - 0.061 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 NmrA-like family Glyco_hydro_18 PF00704.28 KZN87374.1 - 3.8e-80 270.0 0.2 4.6e-80 269.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KZN87374.1 - 7.3e-08 32.8 18.9 1.5e-07 31.8 18.9 1.6 1 0 0 1 1 1 1 Chitin recognition protein GPI2 PF06432.11 KZN87375.1 - 5e-133 442.8 3.3 5.8e-133 442.6 3.3 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Yip1 PF04893.17 KZN87375.1 - 0.0097 15.6 3.5 0.0097 15.6 3.5 2.8 3 0 0 3 3 3 1 Yip1 domain FA_desaturase PF00487.24 KZN87375.1 - 0.27 11.0 4.7 2.6 7.8 3.4 2.2 2 0 0 2 2 2 0 Fatty acid desaturase Fumble PF03630.14 KZN87377.1 - 9.3e-143 475.3 0.1 1.2e-142 475.0 0.1 1.1 1 0 0 1 1 1 1 Fumble DEAD PF00270.29 KZN87378.1 - 2.3e-45 154.5 0.0 4.8e-45 153.5 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KZN87378.1 - 1.1e-26 93.4 0.0 1.9e-24 86.2 0.0 2.5 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 KZN87378.1 - 0.0043 17.1 0.0 0.0086 16.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDC45 PF02724.14 KZN87378.1 - 7.5 4.7 9.2 11 4.2 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Polysacc_deac_1 PF01522.21 KZN87379.1 - 1.5e-17 63.6 0.0 3.4e-17 62.5 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide deacetylase Fringe PF02434.16 KZN87380.1 - 4.2e-09 36.2 0.0 7.1e-08 32.2 0.0 2.3 1 1 0 1 1 1 1 Fringe-like Glyco_transf_34 PF05637.12 KZN87380.1 - 0.065 12.9 0.8 0.23 11.1 0.3 1.9 2 0 0 2 2 2 0 galactosyl transferase GMA12/MNN10 family PAN_4 PF14295.6 KZN87380.1 - 0.28 11.1 1.5 0.56 10.2 1.5 1.5 1 0 0 1 1 1 0 PAN domain DFP PF04127.15 KZN87381.1 - 2.9e-14 53.3 0.0 1.1e-05 25.3 0.0 3.1 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein Abhydrolase_3 PF07859.13 KZN87383.1 - 1.8e-40 139.1 0.0 2.1e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KZN87383.1 - 1.2e-06 28.1 0.0 1.1e-05 25.1 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KZN87383.1 - 0.00028 20.5 0.0 0.024 14.2 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.12 KZN87383.1 - 0.0015 17.3 0.0 0.016 13.9 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 KZN87383.1 - 0.0019 18.8 0.5 0.0026 18.4 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 KZN87383.1 - 0.0024 17.5 0.0 0.0039 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Chlorophyllase2 PF12740.7 KZN87383.1 - 0.0027 16.7 0.0 0.017 14.0 0.0 1.9 2 0 0 2 2 2 1 Chlorophyllase enzyme Esterase PF00756.20 KZN87383.1 - 0.015 15.0 0.0 0.7 9.5 0.0 2.1 2 0 0 2 2 2 0 Putative esterase Abhydrolase_2 PF02230.16 KZN87383.1 - 0.037 13.8 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase BAAT_C PF08840.11 KZN87383.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal CENP-O PF09496.10 KZN87385.1 - 7.4e-69 232.0 0.0 1e-68 231.5 0.0 1.2 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component Acatn PF13000.7 KZN87386.1 - 1.4e-163 545.3 16.6 5.7e-81 272.7 8.8 3.2 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Yae1_N PF09811.9 KZN87389.1 - 2.7e-11 43.0 0.9 5.6e-11 42.0 0.2 1.8 1 1 1 2 2 2 1 Essential protein Yae1, N terminal RNase_T PF00929.24 KZN87392.1 - 1.1e-05 26.0 0.0 2.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Exonuclease zf-C2H2_4 PF13894.6 KZN87392.1 - 1.6e-05 25.3 1.0 0.12 13.3 0.1 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KZN87392.1 - 9.3e-05 22.7 1.3 0.2 12.2 0.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type DUF5051 PF16473.5 KZN87392.1 - 0.00045 20.2 0.0 0.00095 19.2 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like zf-TFIIB PF13453.6 KZN87392.1 - 0.06 12.7 0.4 0.14 11.5 0.4 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger Pribosyl_synth PF14572.6 KZN87392.1 - 0.07 13.2 0.4 0.22 11.5 0.0 2.0 2 0 0 2 2 2 0 Phosphoribosyl synthetase-associated domain zf-Di19 PF05605.12 KZN87392.1 - 0.091 13.1 2.9 0.36 11.2 2.3 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KZN87392.1 - 0.13 12.6 0.2 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Peptidase_M20 PF01546.28 KZN87393.1 - 7.1e-06 25.9 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KZN87393.1 - 9.2e-05 22.3 0.0 0.00085 19.2 0.0 2.3 2 1 0 2 2 2 1 Peptidase dimerisation domain Fungal_trans_2 PF11951.8 KZN87394.1 - 1.2e-15 57.3 2.4 1.7e-08 33.7 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain CMD PF02627.20 KZN87395.1 - 2e-08 34.2 0.0 5e-07 29.7 0.0 2.3 2 1 0 2 2 2 2 Carboxymuconolactone decarboxylase family Lactonase PF10282.9 KZN87396.1 - 3.9e-18 65.8 0.0 6.1e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Abhydrolase_6 PF12697.7 KZN87397.1 - 6.4e-11 43.3 0.9 6.4e-11 43.3 0.9 2.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KZN87397.1 - 2.8e-10 40.3 0.0 1.3e-09 38.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KZN87397.1 - 9.3e-08 31.6 0.0 5.7e-07 29.0 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KZN87397.1 - 0.00022 20.1 0.0 0.00034 19.4 0.0 1.2 1 0 0 1 1 1 1 Ndr family Esterase PF00756.20 KZN87397.1 - 0.0044 16.7 0.0 0.0078 15.9 0.0 1.4 1 0 0 1 1 1 1 Putative esterase EthD PF07110.11 KZN87397.1 - 0.052 14.7 0.3 22 6.3 0.0 3.1 2 1 0 2 2 2 0 EthD domain Abhydrolase_4 PF08386.10 KZN87397.1 - 0.14 12.3 0.0 0.59 10.3 0.0 2.1 2 0 0 2 2 2 0 TAP-like protein Metallophos PF00149.28 KZN87398.1 - 3.1e-35 122.5 0.0 2.9e-34 119.3 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KZN87398.1 - 0.083 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain FAD_binding_3 PF01494.19 KZN87399.1 - 3.7e-80 269.8 0.0 4.6e-80 269.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KZN87399.1 - 4.1e-44 150.5 0.0 8e-44 149.6 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.24 KZN87399.1 - 0.00028 20.1 0.2 0.0006 19.0 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KZN87399.1 - 0.00046 19.5 0.1 0.00076 18.8 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KZN87399.1 - 0.00049 19.4 0.1 0.0011 18.3 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN87399.1 - 0.0005 20.3 0.1 0.0016 18.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KZN87399.1 - 0.0082 15.5 0.3 0.019 14.3 0.4 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KZN87399.1 - 0.011 15.3 0.5 0.031 13.9 0.2 1.7 1 1 0 2 2 2 0 FAD dependent oxidoreductase SE PF08491.10 KZN87399.1 - 0.033 13.2 0.0 0.23 10.4 0.0 2.0 1 1 0 1 1 1 0 Squalene epoxidase Amino_oxidase PF01593.24 KZN87399.1 - 0.047 13.0 0.1 6.9 5.8 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 KZN87399.1 - 0.082 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 KZN87399.1 - 0.14 10.8 0.1 0.21 10.3 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KZN87399.1 - 0.17 12.5 0.0 0.58 10.8 0.0 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_7 PF00840.20 KZN87400.1 - 1.5e-213 709.3 12.3 1.5e-213 709.3 12.3 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 KZN87400.1 - 1.9e-11 43.7 13.5 1.9e-11 43.7 13.5 4.2 4 1 0 4 4 4 1 Fungal cellulose binding domain Sporozoite_P67 PF05642.11 KZN87400.1 - 0.7 7.9 7.8 1.1 7.2 7.8 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Formyl_trans_N PF00551.19 KZN87401.1 - 6e-40 136.9 0.2 7.8e-40 136.5 0.2 1.1 1 0 0 1 1 1 1 Formyl transferase ACT_6 PF13740.6 KZN87401.1 - 2.3e-07 30.7 0.2 1.6e-06 28.0 0.0 2.5 2 2 1 3 3 3 1 ACT domain ACT PF01842.25 KZN87401.1 - 4.2e-07 29.6 0.1 3.1e-06 26.9 0.0 2.4 2 0 0 2 2 2 1 ACT domain NUDIX PF00293.28 KZN87402.1 - 4.7e-07 29.9 0.0 6.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Cellulase PF00150.18 KZN87403.1 - 3.2e-58 197.4 0.6 4.4e-58 196.9 0.6 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KZN87403.1 - 5.3e-11 42.3 10.1 5.3e-11 42.3 10.1 2.6 3 0 0 3 3 3 1 Fungal cellulose binding domain Aconitase PF00330.20 KZN87404.1 - 6.1e-45 154.1 0.7 8.6e-32 110.7 0.1 3.2 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KZN87404.1 - 0.0033 17.7 0.0 0.0081 16.5 0.0 1.7 1 0 0 1 1 1 1 Aconitase C-terminal domain Retrotran_gag_2 PF14223.6 KZN87405.1 - 0.00081 19.1 0.1 0.0014 18.3 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4834 PF16118.5 KZN87405.1 - 7.3 7.6 5.8 1.1 10.3 1.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Transp_cyt_pur PF02133.15 KZN87406.1 - 1.1e-129 433.0 48.2 3.4e-127 424.9 48.2 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin CutC PF03932.14 KZN87407.1 - 3.5e-43 147.5 0.0 5.5e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 CutC family DUF1485 PF07364.12 KZN87408.1 - 7.2e-107 356.9 0.1 9.2e-107 356.6 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M81 MlrC_C PF07171.12 KZN87408.1 - 7.1e-54 182.7 0.1 1.1e-53 182.0 0.1 1.3 1 0 0 1 1 1 1 MlrC C-terminus Ribonuc_L-PSP PF01042.21 KZN87409.1 - 1.2e-10 41.5 0.0 1.6e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP polyprenyl_synt PF00348.17 KZN87410.1 - 5.7e-62 209.1 0.1 6.7e-62 208.9 0.1 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase FAD_binding_3 PF01494.19 KZN87411.1 - 3.9e-26 92.1 0.0 1e-25 90.8 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KZN87411.1 - 0.00023 21.4 0.2 0.00072 19.7 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KZN87411.1 - 0.00055 19.3 2.9 0.17 11.1 0.7 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KZN87411.1 - 0.00099 18.8 0.8 0.0029 17.2 0.7 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KZN87411.1 - 0.0042 16.4 0.1 1.6 7.9 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SE PF08491.10 KZN87411.1 - 0.0054 15.8 0.0 1.4 7.9 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox_2 PF07992.14 KZN87411.1 - 0.0059 15.9 0.2 0.043 13.0 0.0 1.8 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KZN87411.1 - 0.014 14.6 0.7 0.025 13.7 0.7 1.4 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 KZN87411.1 - 0.15 10.8 1.7 10 4.8 0.2 2.5 2 1 0 3 3 3 0 Tryptophan halogenase Lycopene_cycl PF05834.12 KZN87411.1 - 0.16 11.0 0.4 0.89 8.5 0.4 1.9 1 1 0 1 1 1 0 Lycopene cyclase protein polyprenyl_synt PF00348.17 KZN87412.1 - 1e-21 77.2 0.0 1.4e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase Glyco_hydro_43 PF04616.14 KZN87413.1 - 3.2e-57 194.1 2.5 1.1e-56 192.2 2.5 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KZN87413.1 - 1.2e-36 126.3 0.0 1.8e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF3425 PF11905.8 KZN87413.1 - 1.2e-22 80.2 2.2 3.5e-22 78.7 2.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KZN87413.1 - 2.9 8.1 9.6 4.7 7.4 9.6 1.3 1 0 0 1 1 1 0 bZIP transcription factor MFS_1 PF07690.16 KZN87414.1 - 8.9e-20 70.9 51.3 4.2e-14 52.2 33.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ACOX PF01756.19 KZN87415.1 - 2.6e-47 160.7 0.0 1.2e-46 158.5 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KZN87415.1 - 1.4e-28 100.0 1.4 3.1e-28 98.8 1.4 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KZN87415.1 - 1.1e-12 48.0 0.0 4.9e-12 45.9 0.0 2.1 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KZN87415.1 - 4.6e-05 23.7 0.5 0.065 13.4 0.0 2.5 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Sugar_tr PF00083.24 KZN87416.1 - 1.7e-98 330.4 26.5 2.1e-98 330.2 26.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN87416.1 - 6.9e-24 84.4 37.3 8.4e-18 64.4 19.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KZN87416.1 - 8e-05 21.3 0.5 8e-05 21.3 0.5 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KZN87417.1 - 1.2e-112 377.1 26.8 1.4e-112 376.9 26.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN87417.1 - 2.2e-19 69.6 31.9 1.3e-15 57.2 8.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KZN87418.1 - 2.2e-44 151.9 42.6 6e-44 150.4 39.7 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.18 KZN87419.1 - 1.7e-07 31.3 11.7 3.2e-07 30.4 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sulfatase PF00884.23 KZN87423.1 - 9.4e-21 74.5 0.6 2.3e-20 73.2 0.6 1.7 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KZN87423.1 - 0.00047 19.9 0.0 0.00078 19.1 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Ndc1_Nup PF09531.10 KZN87423.1 - 3 6.4 6.9 4.6 5.8 6.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RFX_DNA_binding PF02257.15 KZN87424.1 - 1.9e-27 95.7 0.1 4e-27 94.6 0.1 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain PLDc_2 PF13091.6 KZN87425.1 - 1.4e-14 54.1 0.0 0.0013 18.7 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.22 KZN87425.1 - 8e-11 41.7 4.7 3.2e-06 27.1 0.4 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Pribosyltran_N PF13793.6 KZN87426.1 - 2.7e-36 124.0 0.1 3e-35 120.7 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KZN87426.1 - 2.8e-33 115.5 0.1 2.4e-28 99.4 0.1 2.5 2 1 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KZN87426.1 - 1.7e-07 30.9 0.1 8e-05 22.2 0.1 2.4 2 0 0 2 2 2 2 Phosphoribosyl transferase domain Chitin_synth_1 PF01644.17 KZN87426.1 - 0.07 13.1 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Chitin synthase NAD_binding_7 PF13241.6 KZN87427.1 - 3.7e-33 114.1 0.1 6e-33 113.4 0.1 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KZN87427.1 - 2.3e-32 110.4 0.1 3.7e-32 109.8 0.1 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KZN87427.1 - 8.1e-14 50.8 0.0 8.1e-14 50.8 0.0 1.7 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 KZN87427.1 - 0.0047 16.2 0.0 0.0073 15.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KZN87427.1 - 0.011 15.9 0.4 0.026 14.8 0.4 1.6 1 1 0 1 1 1 0 TrkA-N domain ThiF PF00899.21 KZN87427.1 - 0.031 13.6 2.0 0.078 12.3 0.2 2.0 1 1 1 2 2 2 0 ThiF family Shikimate_DH PF01488.20 KZN87427.1 - 0.043 13.9 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 KZN87427.1 - 0.074 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain LSDAT_prok PF18171.1 KZN87427.1 - 0.099 11.9 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote Sec7 PF01369.20 KZN87428.1 - 2.8e-69 232.5 0.5 1e-68 230.6 0.5 2.1 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KZN87428.1 - 5.7e-41 140.1 2.5 5.7e-41 140.1 2.5 3.1 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KZN87428.1 - 5.7e-34 115.8 7.2 1.2e-32 111.6 0.0 5.7 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) DCB PF16213.5 KZN87428.1 - 5.7e-17 62.0 5.0 8.5e-16 58.1 0.4 3.3 3 0 0 3 3 3 2 Dimerisation and cyclophilin-binding domain of Mon2 LTXXQ PF07813.12 KZN87428.1 - 0.27 12.0 3.3 2.6 8.8 0.2 3.7 3 0 0 3 3 3 0 LTXXQ motif family protein 2-oxoacid_dh PF00198.23 KZN87429.1 - 5e-75 251.9 0.2 6.6e-75 251.5 0.2 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KZN87429.1 - 2.7e-17 62.4 0.6 8e-17 60.8 0.6 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KZN87429.1 - 1e-11 44.9 1.2 3.1e-11 43.4 0.7 2.1 2 0 0 2 2 2 1 e3 binding domain DUF3614 PF12267.8 KZN87429.1 - 0.27 11.7 0.1 0.27 11.7 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3614) DUF5353 PF17304.2 KZN87430.1 - 1.4e-32 111.2 2.2 1.8e-32 110.9 2.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5353) AWPM-19 PF05512.11 KZN87430.1 - 0.13 12.4 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 AWPM-19-like family V-SNARE_C PF12352.8 KZN87431.1 - 5.2e-14 52.3 0.3 7.8e-14 51.7 0.3 1.3 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KZN87431.1 - 0.00058 19.7 0.0 0.0009 19.1 0.0 1.3 1 0 0 1 1 1 1 Sec20 Sigma70_r4 PF04545.16 KZN87431.1 - 0.064 12.8 0.3 0.14 11.7 0.3 1.6 1 1 0 1 1 1 0 Sigma-70, region 4 Pox_EPC_I2-L1 PF12575.8 KZN87431.1 - 0.07 13.4 0.1 1 9.7 0.0 2.1 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 Ldh_1_C PF02866.18 KZN87432.1 - 2e-46 158.0 0.0 3.7e-46 157.1 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KZN87432.1 - 3.5e-42 143.8 0.0 6e-42 143.1 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KZN87432.1 - 0.0004 19.5 0.0 0.00056 19.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 KZN87432.1 - 0.043 13.1 0.0 0.76 9.1 0.0 2.7 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.24 KZN87432.1 - 0.075 13.5 0.2 0.64 10.5 0.0 2.5 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain AAA PF00004.29 KZN87433.1 - 3.9e-16 59.7 0.0 1.4e-15 57.9 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KZN87433.1 - 0.00056 20.2 0.6 0.0076 16.5 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KZN87433.1 - 0.00083 19.4 0.0 0.0023 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KZN87433.1 - 0.0027 17.5 1.0 0.022 14.5 0.2 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KZN87433.1 - 0.0077 16.6 0.1 0.0077 16.6 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 KZN87433.1 - 0.0099 16.2 0.3 0.033 14.5 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KZN87433.1 - 0.023 14.5 0.0 0.023 14.5 0.0 3.5 2 1 0 2 2 2 0 AAA domain HbrB PF08539.11 KZN87435.1 - 1e-46 159.0 0.0 2.1e-46 158.0 0.0 1.6 1 0 0 1 1 1 1 HbrB-like Flocculin PF00624.18 KZN87435.1 - 0.78 10.0 3.9 3 8.2 3.9 2.0 1 0 0 1 1 1 0 Flocculin repeat Gon7 PF08738.10 KZN87436.1 - 6.3e-12 45.5 4.0 1.2e-11 44.6 1.1 1.9 1 1 1 2 2 2 2 Gon7 family Vps39_1 PF10366.9 KZN87437.1 - 1e-30 106.2 0.1 4.4e-28 97.7 0.0 3.2 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KZN87437.1 - 3.5e-29 101.5 0.0 7.4e-29 100.4 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 KZN87437.1 - 2e-17 63.7 0.0 4.1e-17 62.7 0.0 1.4 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 KZN87437.1 - 4.2e-10 39.7 5.3 1.2e-08 34.9 3.5 2.6 2 0 0 2 2 2 1 Region in Clathrin and VPS TPR_1 PF00515.28 KZN87437.1 - 0.0023 17.7 1.7 16 5.5 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1471 PF07338.13 KZN87437.1 - 0.02 14.8 0.0 0.069 13.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1471) TPR_7 PF13176.6 KZN87437.1 - 0.078 13.0 1.7 52 4.2 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4358 PF14270.6 KZN87437.1 - 0.12 12.7 0.1 22 5.4 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) PPR PF01535.20 KZN87437.1 - 0.2 12.0 0.2 41 4.7 0.0 4.4 5 0 0 5 5 5 0 PPR repeat ANAPC3 PF12895.7 KZN87437.1 - 0.58 10.4 3.5 12 6.2 0.0 3.3 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KZN87437.1 - 0.61 10.4 3.0 26 5.2 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Herpes_capsid PF06112.11 KZN87437.1 - 0.84 9.7 3.9 2.2 8.3 3.9 1.6 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein TPR_12 PF13424.6 KZN87437.1 - 0.98 9.8 7.2 28 5.1 0.1 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat 6PF2K PF01591.18 KZN87438.1 - 1e-77 260.4 0.0 1.5e-77 259.9 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KZN87438.1 - 4.3e-40 137.5 0.0 7.2e-40 136.8 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) KTI12 PF08433.10 KZN87438.1 - 0.00016 21.2 0.0 0.00025 20.6 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KZN87438.1 - 0.00041 20.5 0.0 0.0013 18.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain RRM_1 PF00076.22 KZN87439.1 - 7.8e-17 60.9 0.0 8.4e-13 48.0 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KZN87439.1 - 0.11 12.6 0.0 0.4 10.8 0.0 2.0 2 0 0 2 2 2 0 Limkain b1 RRM_5 PF13893.6 KZN87439.1 - 0.18 11.4 0.0 0.68 9.5 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sugar_tr PF00083.24 KZN87440.1 - 1.6e-85 287.7 27.9 1.8e-85 287.5 27.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN87440.1 - 9.4e-17 61.0 25.7 9.4e-17 61.0 25.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 KZN87441.1 - 3.5e-23 82.1 0.0 5.7e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Amidohydro_2 PF04909.14 KZN87443.1 - 4.2e-37 128.5 2.1 5.5e-37 128.1 1.1 1.6 1 1 1 2 2 2 1 Amidohydrolase Acid_PPase PF12689.7 KZN87443.1 - 0.11 12.4 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Acid Phosphatase RINGv PF12906.7 KZN87445.1 - 7.9e-08 32.3 7.4 8.3e-08 32.2 3.3 2.3 2 0 0 2 2 2 1 RING-variant domain zf-BED PF02892.15 KZN87445.1 - 0.08 13.0 0.3 0.08 13.0 0.3 1.9 2 0 0 2 2 2 0 BED zinc finger zf-RING_2 PF13639.6 KZN87445.1 - 0.96 9.8 6.7 4.7 7.6 3.7 2.2 2 0 0 2 2 2 0 Ring finger domain PHD PF00628.29 KZN87445.1 - 6.7 6.7 8.6 1.9 8.4 5.3 1.7 2 0 0 2 2 2 0 PHD-finger PHD_4 PF16866.5 KZN87445.1 - 7.5 6.7 7.4 38 4.5 7.5 2.1 1 1 0 1 1 1 0 PHD-finger Proteasome PF00227.26 KZN87446.1 - 7e-57 192.0 0.0 7.2e-32 110.4 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KZN87446.1 - 8.8e-11 41.3 0.1 3.1e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_S13 PF02113.15 KZN87446.1 - 0.058 12.1 0.1 0.81 8.3 0.0 2.0 2 0 0 2 2 2 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family Rad51 PF08423.11 KZN87448.1 - 3e-14 52.9 0.0 1.2e-13 51.0 0.0 1.9 1 1 0 1 1 1 1 Rad51 RecA PF00154.21 KZN87448.1 - 3.3e-07 30.1 0.0 6e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KZN87448.1 - 1e-05 25.0 0.0 2.3e-05 23.9 0.0 1.5 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.6 KZN87448.1 - 0.00036 20.2 0.0 0.0013 18.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KZN87448.1 - 0.0025 17.6 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.16 KZN87448.1 - 0.0071 15.8 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_24 PF13479.6 KZN87448.1 - 0.022 14.5 0.0 0.059 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KZN87448.1 - 0.024 15.1 0.0 0.047 14.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KZN87448.1 - 0.024 15.0 0.0 0.053 13.9 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain DnaB_C PF03796.15 KZN87448.1 - 0.038 13.3 0.0 0.089 12.1 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain ABC_tran PF00005.27 KZN87448.1 - 0.058 13.9 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 KZN87448.1 - 0.18 12.0 0.0 0.36 11.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KZN87448.1 - 0.19 12.0 0.0 0.69 10.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain MOSC PF03473.17 KZN87449.1 - 7.8e-24 84.2 0.0 1.1e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KZN87449.1 - 3e-07 30.4 0.0 5.1e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain Xan_ur_permease PF00860.20 KZN87451.1 - 9.3e-63 212.2 29.6 2.4e-62 210.9 29.6 1.6 1 1 0 1 1 1 1 Permease family FA_desaturase PF00487.24 KZN87452.1 - 2.1e-20 73.6 13.0 2.1e-20 73.6 13.0 1.4 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 KZN87452.1 - 1.4e-16 60.4 0.2 4.1e-16 58.9 0.1 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DUF2225 PF09986.9 KZN87452.1 - 0.014 15.2 0.0 0.035 13.8 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF1189 PF06691.11 KZN87452.1 - 0.092 12.3 0.3 0.19 11.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) Peptidase_M3 PF01432.20 KZN87453.1 - 6.7e-162 539.9 0.0 9e-162 539.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 SUV3_C PF12513.8 KZN87453.1 - 0.019 14.9 0.1 0.056 13.4 0.1 1.8 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal EF-hand_7 PF13499.6 KZN87455.1 - 1e-11 45.1 0.5 4.9e-08 33.3 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KZN87455.1 - 1.1e-09 38.4 0.0 0.00057 20.2 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 KZN87455.1 - 3.1e-08 32.9 1.9 0.014 15.3 0.1 3.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 KZN87455.1 - 3.7e-07 29.2 1.2 0.025 14.1 0.0 3.8 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 KZN87455.1 - 2.3e-06 27.3 0.1 0.00011 21.9 0.1 2.9 3 0 0 3 3 3 1 EF-hand domain pair DUF3216 PF11505.8 KZN87455.1 - 0.15 12.3 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) Fungal_trans PF04082.18 KZN87456.1 - 4.3e-67 226.0 0.3 5.8e-67 225.5 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KZN87456.1 - 0.00039 20.7 15.5 0.0014 19.0 0.8 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KZN87456.1 - 0.018 15.5 6.5 0.027 14.9 1.6 2.8 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KZN87456.1 - 0.022 15.6 10.1 0.086 13.7 0.8 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Xpo1 PF08389.12 KZN87457.1 - 1.5e-26 93.2 0.1 4.7e-25 88.4 0.0 3.2 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 KZN87457.1 - 1.3e-05 25.0 0.0 7.7e-05 22.5 0.0 2.4 3 0 0 3 3 3 1 Importin-beta N-terminal domain LSM PF01423.22 KZN87458.1 - 5.1e-14 51.7 0.0 5.8e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KZN87458.1 - 0.0019 17.8 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 Hfq protein 5-FTHF_cyc-lig PF01812.20 KZN87459.1 - 9.2e-36 123.4 0.0 1.1e-35 123.2 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family ATP-grasp_6 PF18419.1 KZN87459.1 - 0.079 12.6 0.4 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp-like domain Rot1 PF10681.9 KZN87460.1 - 2.9e-92 307.9 0.0 3.3e-92 307.7 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal YqeY PF09424.10 KZN87461.1 - 5.7e-20 71.9 2.6 6.5e-20 71.7 2.6 1.0 1 0 0 1 1 1 1 Yqey-like protein Nucleoporin_N PF08801.11 KZN87462.1 - 2.8e-89 299.9 0.4 4.4e-89 299.2 0.4 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KZN87462.1 - 8.2e-48 163.5 1.2 6.9e-45 153.9 0.2 2.1 2 0 0 2 2 2 2 Non-repetitive/WGA-negative nucleoporin C-terminal Imm35 PF15567.6 KZN87462.1 - 0.072 13.3 0.0 0.55 10.4 0.0 2.3 2 0 0 2 2 2 0 Immunity protein 35 Forkhead_N PF08430.12 KZN87462.1 - 0.37 11.4 5.6 0.088 13.4 1.1 2.2 2 0 0 2 2 2 0 Forkhead N-terminal region TauD PF02668.16 KZN87463.1 - 1.2e-46 159.7 0.1 1.5e-46 159.4 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family UPF0302 PF08864.10 KZN87463.1 - 0.027 14.5 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 UPF0302 domain DUF2781 PF10914.8 KZN87464.1 - 2.2e-41 141.7 11.9 2.6e-41 141.5 11.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Asp_protease PF09668.10 KZN87465.1 - 8.7e-61 203.2 0.1 1.3e-60 202.6 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KZN87465.1 - 8.5e-22 77.5 0.0 1.8e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KZN87465.1 - 1.6e-10 41.5 0.0 4e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.23 KZN87465.1 - 2.3e-09 36.9 0.0 3.7e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KZN87465.1 - 9.4e-06 25.4 0.2 2.4e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.8 KZN87465.1 - 0.0012 18.6 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RVP_2 PF08284.11 KZN87465.1 - 0.0012 18.6 0.0 0.0025 17.6 0.0 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 KZN87465.1 - 0.0034 17.7 0.0 0.039 14.2 0.0 2.5 2 0 0 2 2 2 1 Retroviral aspartyl protease UBA_4 PF14555.6 KZN87465.1 - 0.017 14.9 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain NAD_binding_7 PF13241.6 KZN87465.1 - 0.17 12.3 0.1 0.67 10.4 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding CDC45 PF02724.14 KZN87466.1 - 2 6.6 6.3 3.5 5.8 6.3 1.3 1 0 0 1 1 1 0 CDC45-like protein ThiF PF00899.21 KZN87467.1 - 1.1e-27 96.9 0.0 1.5e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 ThiF family Ytp1 PF10355.9 KZN87468.1 - 1.6e-70 237.5 19.8 1.6e-70 237.5 19.8 2.3 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KZN87468.1 - 1.9e-32 111.2 1.3 1.9e-32 111.2 1.3 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DUF3180 PF11377.8 KZN87468.1 - 5.2 7.2 13.1 15 5.7 5.5 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3180) Cytochrom_B561 PF03188.16 KZN87468.1 - 6.2 7.0 28.1 0.023 14.8 11.7 4.1 4 1 0 4 4 4 0 Eukaryotic cytochrome b561 ABC_membrane PF00664.23 KZN87469.1 - 1.4e-95 320.1 35.4 7.3e-49 166.9 13.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KZN87469.1 - 6.5e-68 227.5 0.0 5.8e-33 114.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KZN87469.1 - 1.6e-14 53.9 0.0 1.6e-05 24.5 0.8 4.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KZN87469.1 - 4.2e-08 33.7 2.7 0.0097 16.3 0.1 3.7 2 2 1 3 3 3 2 AAA ATPase domain ABC_ATPase PF09818.9 KZN87469.1 - 1.9e-07 30.2 0.6 0.012 14.5 0.0 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA PF00004.29 KZN87469.1 - 2.3e-07 31.3 0.1 4.6 7.7 0.0 4.7 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KZN87469.1 - 9.1e-07 28.5 1.1 0.0061 16.3 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KZN87469.1 - 6.5e-06 26.5 3.0 0.037 14.3 0.1 3.9 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KZN87469.1 - 2.6e-05 24.2 0.0 0.46 10.4 0.0 2.9 3 0 0 3 3 2 2 RsgA GTPase AAA_21 PF13304.6 KZN87469.1 - 3.4e-05 23.8 0.1 0.13 12.0 0.0 3.5 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KZN87469.1 - 4e-05 23.4 3.2 0.53 10.0 0.0 4.3 5 0 0 5 5 5 2 AAA domain Rad17 PF03215.15 KZN87469.1 - 0.0003 20.8 0.1 0.029 14.3 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_25 PF13481.6 KZN87469.1 - 0.00063 19.4 0.6 0.46 10.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 KZN87469.1 - 0.0016 18.5 0.6 4 7.4 0.0 3.2 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KZN87469.1 - 0.0016 19.0 0.0 2.1 8.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KZN87469.1 - 0.0025 18.0 0.0 2.8 8.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KZN87469.1 - 0.0032 17.2 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 KZN87469.1 - 0.0033 17.6 3.1 3.4 8.0 0.3 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KZN87469.1 - 0.0049 17.4 0.1 3.7 8.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KZN87469.1 - 0.0075 15.8 0.1 1.5 8.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region SRP54 PF00448.22 KZN87469.1 - 0.012 15.2 0.2 1.6 8.3 0.0 2.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KZN87469.1 - 0.014 15.1 0.1 2.4 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KZN87469.1 - 0.015 15.7 0.0 4 7.9 0.0 3.3 3 0 0 3 3 2 0 RNA helicase Tho1_MOS11_C PF18592.1 KZN87469.1 - 0.041 13.7 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 Tho1/MOS11 C-terminal domain PRK PF00485.18 KZN87469.1 - 0.043 13.6 0.1 2.7 7.7 0.0 2.7 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family Cytidylate_kin PF02224.18 KZN87469.1 - 0.046 13.4 0.0 3.6 7.3 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase AAA_28 PF13521.6 KZN87469.1 - 0.046 13.9 0.9 1.3 9.2 0.1 2.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KZN87469.1 - 0.081 12.2 0.0 11 5.2 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin DUF2207 PF09972.9 KZN87469.1 - 0.13 11.0 0.0 0.13 11.0 0.0 3.8 4 1 0 4 4 3 0 Predicted membrane protein (DUF2207) G-alpha PF00503.20 KZN87469.1 - 0.14 11.3 0.0 8.9 5.4 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit AAA_17 PF13207.6 KZN87469.1 - 0.2 12.1 1.9 23 5.4 0.2 3.4 4 0 0 4 4 2 0 AAA domain APH PF01636.23 KZN87470.1 - 3.5e-08 33.7 0.0 3.8e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN87470.1 - 5e-05 23.0 0.0 5.7e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase HERV-K_env_2 PF13804.6 KZN87470.1 - 0.026 14.3 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 Retro-transcribing viruses envelope glycoprotein Pkinase PF00069.25 KZN87470.1 - 0.036 13.4 0.0 0.047 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain RIO1 PF01163.22 KZN87470.1 - 0.085 12.5 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Ribosomal_L39 PF00832.20 KZN87471.1 - 2.5e-21 75.0 12.5 2.9e-21 74.8 12.5 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Skp1 PF01466.19 KZN87472.1 - 2.7e-28 97.8 0.5 4.5e-28 97.1 0.5 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KZN87472.1 - 3.1e-24 84.9 0.2 7.8e-24 83.6 0.1 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Glyco_transf_22 PF03901.17 KZN87473.1 - 2.3e-47 162.2 20.3 2.8e-47 161.9 20.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family XPC-binding PF09280.11 KZN87474.1 - 8.9e-23 79.8 11.8 1.6e-22 79.0 11.8 1.4 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 KZN87474.1 - 5.3e-22 77.3 2.4 7.1e-13 48.2 0.1 2.4 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 KZN87474.1 - 3.2e-20 71.6 1.1 3.2e-20 71.6 1.1 1.8 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 KZN87474.1 - 3.7e-07 29.9 2.7 7.4e-07 28.9 2.7 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KZN87474.1 - 0.00017 21.9 0.2 0.00029 21.1 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KZN87474.1 - 0.00054 20.0 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KZN87474.1 - 0.0035 17.9 0.1 0.0078 16.8 0.0 1.6 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain UBA_3 PF09288.10 KZN87474.1 - 0.057 13.2 0.0 5.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Arteri_Gl PF00951.18 KZN87475.1 - 0.47 10.2 3.0 0.71 9.7 3.0 1.2 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein DUF3792 PF12670.7 KZN87475.1 - 2.3 8.4 10.7 12 6.1 10.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3792) DUF5320 PF17253.2 KZN87476.1 - 0.39 11.8 13.8 14 6.8 0.1 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5320) eIF-6 PF01912.18 KZN87477.1 - 7.2e-80 267.0 0.8 9.5e-80 266.6 0.8 1.2 1 0 0 1 1 1 1 eIF-6 family SRI PF08236.11 KZN87478.1 - 3.3e-18 65.6 9.1 8.8e-18 64.3 9.1 1.8 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 KZN87478.1 - 7.7e-17 62.2 1.3 2.4e-16 60.6 0.2 2.5 2 1 0 2 2 2 1 SET domain AWS PF17907.1 KZN87478.1 - 6.6e-11 42.1 9.2 6.6e-11 42.1 9.2 2.1 2 0 0 2 2 2 1 AWS domain WW PF00397.26 KZN87478.1 - 0.00024 21.1 1.8 0.00065 19.7 1.8 1.8 1 0 0 1 1 1 1 WW domain Med26 PF08711.11 KZN87478.1 - 0.0038 17.2 0.7 0.01 15.8 0.1 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain AT_hook PF02178.19 KZN87479.1 - 0.0038 16.9 1.3 0.021 14.6 1.3 2.4 1 0 0 1 1 1 1 AT hook motif Myb_DNA-binding PF00249.31 KZN87479.1 - 0.033 14.4 0.1 0.18 12.0 0.1 2.0 1 1 0 1 1 1 0 Myb-like DNA-binding domain Pkinase PF00069.25 KZN87480.1 - 9.8e-53 179.2 0.0 7.3e-47 159.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KZN87480.1 - 8.3e-34 117.0 0.0 4.7e-32 111.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KZN87480.1 - 6.8e-08 32.2 0.0 1.7e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KZN87480.1 - 0.0028 17.6 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KZN87480.1 - 0.0034 16.2 0.2 0.022 13.5 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Sybindin PF04099.12 KZN87481.1 - 4.5e-24 85.0 0.0 5.4e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KZN87481.1 - 0.05 13.7 0.1 0.072 13.2 0.1 1.2 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region Pkinase PF00069.25 KZN87482.1 - 1.7e-47 162.0 0.0 3.1e-47 161.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN87482.1 - 2.1e-26 92.8 0.0 3.2e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KZN87482.1 - 0.0049 16.2 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KZN87482.1 - 0.01 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KZN87482.1 - 0.029 14.3 2.4 1.3 8.9 0.0 3.7 3 1 1 4 4 4 0 Phosphotransferase enzyme family Hamartin PF04388.12 KZN87482.1 - 1.8 7.1 8.2 2.4 6.7 8.2 1.2 1 0 0 1 1 1 0 Hamartin protein BAR PF03114.18 KZN87483.1 - 3.5e-64 216.7 5.1 4.2e-64 216.4 5.1 1.1 1 0 0 1 1 1 1 BAR domain DUF3340 PF11818.8 KZN87483.1 - 0.0052 16.9 0.8 0.0052 16.9 0.8 1.8 2 0 0 2 2 2 1 C-terminal domain of tail specific protease (DUF3340) CP12 PF02672.15 KZN87483.1 - 0.014 16.2 0.1 0.075 13.8 0.0 2.3 2 1 0 2 2 2 0 CP12 domain Pept_tRNA_hydro PF01195.19 KZN87484.1 - 2.5e-17 63.4 0.0 2e-14 53.9 0.0 2.7 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase Ploopntkinase3 PF18751.1 KZN87484.1 - 0.049 13.5 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Brix PF04427.18 KZN87486.1 - 2.2e-24 86.6 0.0 3.9e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Brix domain BUD22 PF09073.10 KZN87486.1 - 0.042 13.2 19.0 0.057 12.8 19.0 1.1 1 0 0 1 1 1 0 BUD22 Hid1 PF12722.7 KZN87486.1 - 0.84 7.7 6.1 0.98 7.5 6.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein HGTP_anticodon PF03129.20 KZN87487.1 - 1.2e-21 76.7 0.0 1.2e-21 76.7 0.0 2.6 3 1 0 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KZN87487.1 - 4.7e-08 33.2 0.0 2.7e-07 30.7 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) RPN2_C PF18004.1 KZN87487.1 - 0.34 10.8 5.0 0.86 9.5 5.0 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Pkinase PF00069.25 KZN87489.1 - 2.1e-66 224.0 0.7 2.1e-66 224.0 0.7 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN87489.1 - 9.9e-51 172.5 0.1 1.7e-50 171.8 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KZN87489.1 - 8.8e-25 86.8 0.4 8.5e-24 83.7 0.0 2.5 2 0 0 2 2 2 1 P21-Rho-binding domain PH_11 PF15413.6 KZN87489.1 - 9.2e-12 45.3 0.1 2.4e-11 44.0 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.6 KZN87489.1 - 5.5e-06 25.9 0.0 9.3e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KZN87489.1 - 8.7e-05 21.5 0.0 8.7e-05 21.5 0.0 2.0 3 0 0 3 3 3 1 Fungal protein kinase PH PF00169.29 KZN87489.1 - 0.00018 22.0 0.1 0.00042 20.8 0.1 1.6 1 0 0 1 1 1 1 PH domain Haspin_kinase PF12330.8 KZN87489.1 - 0.0017 17.3 0.1 0.0031 16.5 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KZN87489.1 - 0.015 15.2 0.3 0.046 13.6 0.3 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KZN87489.1 - 0.042 12.9 0.0 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 NAD_kinase PF01513.21 KZN87490.1 - 7.6e-49 166.5 0.0 1.1e-48 165.9 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KZN87490.1 - 0.014 15.1 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Acyltransferase PF01553.21 KZN87491.1 - 1e-26 93.2 0.0 1.5e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KZN87491.1 - 4.6e-14 52.3 0.1 8.7e-14 51.4 0.1 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus TPR_2 PF07719.17 KZN87492.1 - 5.8e-25 85.4 29.8 0.00031 20.6 0.4 11.7 12 0 0 12 12 11 7 Tetratricopeptide repeat TPR_1 PF00515.28 KZN87492.1 - 1.4e-21 75.3 17.3 0.0014 18.4 0.0 10.5 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_19 PF14559.6 KZN87492.1 - 9.3e-17 61.3 29.8 2.1e-05 24.9 0.1 8.7 10 1 1 11 11 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 KZN87492.1 - 5.2e-11 42.4 31.3 0.1 13.5 0.1 11.5 11 1 1 12 12 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 KZN87492.1 - 6.1e-11 41.6 15.8 0.29 11.5 0.0 9.8 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 KZN87492.1 - 3.1e-08 33.1 9.4 0.73 9.6 0.2 7.5 7 1 1 8 8 8 3 TPR repeat TPR_6 PF13174.6 KZN87492.1 - 1.9e-07 31.3 27.0 0.034 14.8 0.0 12.4 14 0 0 14 14 13 2 Tetratricopeptide repeat TPR_7 PF13176.6 KZN87492.1 - 2.9e-07 30.0 21.1 0.0074 16.2 0.0 8.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 KZN87492.1 - 2.7e-06 27.9 29.5 0.063 13.9 0.5 8.6 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 KZN87492.1 - 2.3e-05 24.5 11.6 1.1 9.8 0.0 9.4 11 0 0 11 11 9 1 Tetratricopeptide repeat TPR_12 PF13424.6 KZN87492.1 - 5.3e-05 23.4 30.5 0.028 14.7 0.2 8.5 8 3 3 11 11 9 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KZN87492.1 - 0.025 14.8 11.0 13 6.1 0.0 6.6 7 1 0 7 7 6 0 Anaphase-promoting complex, cyclosome, subunit 3 GGDEF_2 PF17853.1 KZN87492.1 - 0.045 14.0 0.0 0.3 11.3 0.0 2.5 2 0 0 2 2 2 0 GGDEF-like domain TPR_10 PF13374.6 KZN87492.1 - 0.3 11.0 29.6 2.8 7.9 0.1 8.7 9 0 0 9 9 8 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KZN87492.1 - 0.5 10.5 3.6 12 6.0 0.1 3.8 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF2330 PF10092.9 KZN87493.1 - 0.099 11.7 0.1 0.1 11.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) Transglut_core3 PF13471.6 KZN87495.1 - 0.12 12.2 0.7 2.9 7.8 0.0 2.2 2 0 0 2 2 2 0 Transglutaminase-like superfamily Es2 PF09751.9 KZN87496.1 - 6.3e-136 454.6 10.8 7.3e-136 454.3 10.8 1.0 1 0 0 1 1 1 1 Nuclear protein Es2 APOC4 PF15119.6 KZN87496.1 - 0.062 13.6 0.1 7.5 6.9 0.0 2.5 2 0 0 2 2 2 0 Apolipoprotein C4 Mid1 PF12929.7 KZN87497.1 - 7.9e-160 532.7 5.6 1.1e-159 532.3 5.6 1.2 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 KZN87497.1 - 0.0026 18.4 8.4 0.1 13.2 4.5 2.9 2 1 0 2 2 2 2 Fz domain CorA PF01544.18 KZN87498.1 - 1.4e-43 149.3 0.0 1.9e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein GHMP_kinases_N PF00288.26 KZN87499.1 - 1.8e-10 40.9 0.0 3.6e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KZN87499.1 - 1e-05 25.8 0.0 2.1e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal SPC12 PF06645.13 KZN87500.1 - 2.8e-29 101.0 0.2 3.3e-29 100.8 0.2 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) ZYG-11_interact PF05884.12 KZN87500.1 - 0.034 13.6 0.1 0.036 13.5 0.1 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 zf-rbx1 PF12678.7 KZN87501.1 - 3.7e-25 88.0 12.8 5.3e-25 87.5 12.8 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KZN87501.1 - 1.9e-17 63.1 10.3 2.5e-17 62.7 10.3 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KZN87501.1 - 2.8e-06 27.6 14.8 9.9e-05 22.6 14.8 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KZN87501.1 - 9.9e-05 22.1 3.7 9.9e-05 22.1 3.7 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KZN87501.1 - 0.0014 18.4 11.9 0.026 14.4 11.9 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KZN87501.1 - 0.2 11.8 9.2 0.87 9.8 9.3 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 KZN87501.1 - 0.26 11.2 10.6 0.63 9.9 4.4 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KZN87501.1 - 0.43 10.6 7.8 1.6 8.8 7.8 2.0 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KZN87501.1 - 0.6 9.8 14.7 0.11 12.1 4.6 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KZN87501.1 - 1 9.2 17.1 95 2.9 17.1 2.5 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 KZN87501.1 - 8.5 6.4 11.4 48 4.0 11.4 2.3 1 1 0 1 1 1 0 zinc-RING finger domain PNRC PF15365.6 KZN87502.1 - 9.3e-09 34.9 7.7 9.3e-09 34.9 7.7 5.6 6 0 0 6 6 6 1 Proline-rich nuclear receptor coactivator motif SMI1_KNR4 PF09346.10 KZN87504.1 - 3.6e-32 111.6 0.0 9.4e-32 110.2 0.0 1.8 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_5 PF14567.6 KZN87504.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall MRP-S32 PF10210.9 KZN87504.1 - 0.19 12.3 1.2 1.3 9.7 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S32 Thioredoxin PF00085.20 KZN87505.1 - 0.00029 20.8 0.0 0.00048 20.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin EamA PF00892.20 KZN87506.1 - 1.8e-05 24.9 6.9 1.8e-05 24.9 6.9 2.2 2 0 0 2 2 2 1 EamA-like transporter family DUF1077 PF06417.12 KZN87506.1 - 0.38 10.8 5.0 2.7 8.0 0.2 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF1077) zf-C2H2_jaz PF12171.8 KZN87507.1 - 2.3e-10 40.5 4.1 0.029 14.7 0.1 3.4 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KZN87507.1 - 4.4e-09 36.4 6.4 0.014 15.7 0.3 3.6 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KZN87507.1 - 3.2e-08 33.8 7.2 0.25 12.3 0.1 3.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KZN87507.1 - 3.7e-06 27.1 8.8 0.11 13.0 0.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KZN87507.1 - 0.00012 21.9 9.6 0.17 11.9 1.5 3.4 2 1 1 3 3 3 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KZN87507.1 - 0.12 12.8 9.4 0.18 12.2 6.2 3.0 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) ADK_lid PF05191.14 KZN87507.1 - 0.62 10.1 6.3 11 6.2 3.4 2.7 2 1 0 2 2 2 0 Adenylate kinase, active site lid FYVE PF01363.21 KZN87507.1 - 0.9 9.7 6.1 0.098 12.8 1.6 1.8 2 0 0 2 2 2 0 FYVE zinc finger zf-C2H2_11 PF16622.5 KZN87507.1 - 3.6 7.4 9.5 14 5.6 0.1 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type DUF2431 PF10354.9 KZN87508.1 - 1.4e-62 210.9 0.0 1.9e-62 210.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Ribosomal_L19e PF01280.20 KZN87508.1 - 0.011 15.8 0.6 0.039 14.0 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L19e CLTH PF10607.9 KZN87509.1 - 1.4e-36 125.6 1.0 2.6e-36 124.7 1.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain YhdB PF14148.6 KZN87509.1 - 0.0085 16.2 0.4 0.056 13.6 0.1 2.3 2 0 0 2 2 2 1 YhdB-like protein LisH PF08513.11 KZN87509.1 - 0.085 12.9 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 LisH UL73_N PF12522.8 KZN87509.1 - 0.44 10.4 8.5 1 9.2 8.5 1.6 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal DKCLD PF08068.12 KZN87510.1 - 1.6e-32 111.3 0.1 4.5e-31 106.7 0.2 2.5 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 KZN87510.1 - 4.3e-23 81.2 0.3 8.3e-23 80.3 0.3 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 KZN87510.1 - 4.8e-22 78.9 1.5 3e-19 69.9 0.2 3.8 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 KZN87510.1 - 2.2e-21 75.6 1.3 4.5e-21 74.6 1.3 1.5 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KZN87510.1 - 0.0014 18.8 0.0 0.0035 17.6 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain RNA_polI_A34 PF08208.11 KZN87510.1 - 0.96 9.5 23.2 1.5 8.9 23.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF3987 PF13148.6 KZN87510.1 - 1.2 8.0 6.8 1.6 7.7 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) TFIIF_alpha PF05793.12 KZN87510.1 - 7.2 5.1 25.4 10 4.6 25.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Vfa1 PF08432.10 KZN87510.1 - 9.2 6.6 17.7 18 5.6 17.7 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DER1 PF04511.15 KZN87511.1 - 1.4e-26 93.6 6.6 1.7e-26 93.4 6.6 1.0 1 0 0 1 1 1 1 Der1-like family MaoC_dehydratas PF01575.19 KZN87512.1 - 0.0052 16.3 0.0 0.0089 15.6 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain PDT PF00800.18 KZN87513.1 - 8.6e-62 208.2 0.0 1.2e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 KZN87513.1 - 0.00029 20.5 0.0 0.00068 19.4 0.0 1.6 1 0 0 1 1 1 1 ACT domain eRF1_2 PF03464.15 KZN87514.1 - 5.8e-45 152.9 0.0 1e-44 152.1 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KZN87514.1 - 2e-37 128.1 0.6 4.3e-37 127.0 0.6 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KZN87514.1 - 3.8e-22 78.7 0.0 7.8e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 KZN87514.1 - 1.1e-07 32.1 0.0 2.2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 KZN87514.1 - 1.4e-07 31.9 0.0 2.7e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor Ribosomal_L7Ae PF01248.26 KZN87514.1 - 0.1 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Aa_trans PF01490.18 KZN87515.1 - 1.2e-67 228.5 26.6 1.4e-67 228.2 26.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MerC PF03203.14 KZN87515.1 - 0.017 15.6 1.2 0.017 15.6 1.2 3.6 3 1 0 3 3 3 0 MerC mercury resistance protein Bmt2 PF11968.8 KZN87516.1 - 9.6e-93 310.1 0.0 1.2e-92 309.8 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 KZN87516.1 - 0.089 12.6 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L23eN PF03939.13 KZN87517.1 - 2.3e-23 82.1 7.4 4.3e-23 81.3 7.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 KZN87517.1 - 2.6e-15 56.5 1.4 5.1e-15 55.6 1.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 zf-Tim10_DDP PF02953.15 KZN87518.1 - 1.1e-21 76.2 2.5 1.5e-21 75.8 2.5 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger G10 PF01125.17 KZN87519.1 - 5.6e-68 227.3 4.8 6.3e-68 227.1 4.8 1.0 1 0 0 1 1 1 1 G10 protein Forkhead PF00250.18 KZN87520.1 - 2e-35 120.9 0.1 3.4e-35 120.1 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain AA_kinase PF00696.28 KZN87521.1 - 3.2e-40 138.2 0.0 5.6e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 KZN87521.1 - 5.9e-11 42.0 1.3 1.3e-08 34.5 0.1 2.4 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 KZN87521.1 - 4.9e-09 35.8 1.9 2.4e-06 27.2 0.1 3.3 3 0 0 3 3 3 2 ACT domain Peptidase_C78 PF07910.13 KZN87523.1 - 1.4e-69 233.8 0.0 1.9e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 zf_UBZ PF18439.1 KZN87523.1 - 0.00019 21.0 0.2 0.00044 19.8 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 KZN87523.1 - 0.034 14.5 3.6 5.6 7.3 0.1 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding AAA_18 PF13238.6 KZN87524.1 - 2.3e-26 92.9 0.4 5.1e-26 91.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KZN87524.1 - 1.8e-08 34.9 0.0 4.3e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KZN87524.1 - 0.00019 21.9 0.0 0.00033 21.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KZN87524.1 - 0.00081 19.8 0.1 0.0028 18.1 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain ADK PF00406.22 KZN87524.1 - 0.0029 17.7 0.1 0.022 14.8 0.1 2.1 1 1 0 2 2 2 1 Adenylate kinase RNA_helicase PF00910.22 KZN87524.1 - 0.0031 17.9 0.0 0.006 16.9 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 KZN87524.1 - 0.0033 17.7 0.0 0.0063 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KZN87524.1 - 0.0063 16.7 0.0 0.018 15.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KZN87524.1 - 0.0064 16.4 0.2 0.016 15.2 0.1 1.7 2 0 0 2 2 2 1 NTPase AAA_22 PF13401.6 KZN87524.1 - 0.01 16.1 0.0 0.021 15.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KZN87524.1 - 0.017 15.2 0.0 0.037 14.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 KZN87524.1 - 0.02 14.3 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Hydin_ADK PF17213.3 KZN87524.1 - 0.032 14.5 0.0 0.057 13.7 0.0 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF2075 PF09848.9 KZN87524.1 - 0.033 13.4 0.1 0.1 11.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.11 KZN87524.1 - 0.042 13.7 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.6 KZN87524.1 - 0.046 13.9 0.0 0.11 12.6 0.0 1.8 1 1 0 1 1 1 0 Cytidylate kinase-like family dNK PF01712.19 KZN87524.1 - 0.098 12.5 0.1 11 5.8 0.1 2.3 1 1 0 2 2 2 0 Deoxynucleoside kinase NACHT PF05729.12 KZN87524.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 KZN87524.1 - 0.18 11.8 0.0 0.43 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KZN87524.1 - 0.18 11.5 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 KZN87524.1 - 0.2 12.0 0.2 0.23 11.8 0.2 1.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KZN87524.1 - 0.21 11.1 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 KZN87524.1 - 0.43 10.3 1.8 2.1 8.0 0.3 2.3 2 1 1 3 3 3 0 AAA domain Ham1p_like PF01725.16 KZN87525.1 - 2e-61 207.2 0.0 2.3e-61 207.0 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Myosin_head PF00063.21 KZN87526.1 - 2.3e-265 882.0 0.7 3.2e-265 881.6 0.7 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 KZN87526.1 - 4.1e-26 91.3 2.1 4.1e-26 91.3 2.1 2.7 2 1 1 3 3 3 1 DIL domain IQ PF00612.27 KZN87526.1 - 2.3e-12 45.5 28.6 0.0003 20.3 0.5 6.7 6 0 0 6 6 6 4 IQ calmodulin-binding motif Myosin_N PF02736.19 KZN87526.1 - 1.3e-05 24.9 0.7 3.3e-05 23.6 0.7 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain GAS PF13851.6 KZN87526.1 - 8.9e-05 21.9 29.5 0.0083 15.5 14.8 2.7 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding AAA_22 PF13401.6 KZN87526.1 - 0.0016 18.7 0.0 0.0085 16.4 0.0 2.3 2 0 0 2 2 1 1 AAA domain RsgA_GTPase PF03193.16 KZN87526.1 - 0.0029 17.5 0.0 0.0094 15.9 0.0 1.9 1 0 0 1 1 1 1 RsgA GTPase TMP_2 PF06791.13 KZN87526.1 - 0.012 15.2 1.7 0.025 14.2 1.7 1.4 1 0 0 1 1 1 0 Prophage tail length tape measure protein AAA_16 PF13191.6 KZN87526.1 - 0.018 15.4 3.3 0.022 15.1 0.0 2.7 2 1 0 2 2 1 0 AAA ATPase domain Pox_A_type_inc PF04508.12 KZN87526.1 - 0.03 14.2 0.3 0.03 14.2 0.3 2.7 2 0 0 2 2 1 0 Viral A-type inclusion protein repeat T2SSE PF00437.20 KZN87526.1 - 0.031 13.3 0.0 0.08 12.0 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Tropomyosin_1 PF12718.7 KZN87526.1 - 0.28 11.4 28.7 2.8 8.1 18.0 2.8 1 1 1 2 2 2 0 Tropomyosin like FliJ PF02050.16 KZN87526.1 - 0.28 11.4 23.8 0.024 14.8 15.6 3.2 1 1 1 2 2 2 0 Flagellar FliJ protein Sec34 PF04136.15 KZN87526.1 - 0.3 10.9 6.6 1.1 9.1 6.6 2.1 1 0 0 1 1 1 0 Sec34-like family Herpes_BLRF2 PF05812.12 KZN87526.1 - 1.2 9.3 12.4 0.073 13.2 5.2 2.7 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein ABC_tran PF00005.27 KZN87526.1 - 1.3 9.5 3.6 1.6 9.2 0.0 2.7 2 1 0 2 2 2 0 ABC transporter Phage_GP20 PF06810.11 KZN87526.1 - 2.7 7.8 18.1 1.3 8.8 2.4 2.9 1 1 0 2 2 2 0 Phage minor structural protein GP20 FUSC PF04632.12 KZN87526.1 - 7.4 5.0 8.7 14 4.0 8.7 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family KASH_CCD PF14662.6 KZN87526.1 - 7.6 6.3 27.4 2 8.2 9.0 2.9 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH APG6_N PF17675.1 KZN87526.1 - 9.3 6.8 38.2 0.41 11.2 23.7 3.7 2 1 1 3 3 3 0 Apg6 coiled-coil region NAP PF00956.18 KZN87527.1 - 6.2e-99 330.6 9.4 6.2e-99 330.6 9.4 1.7 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) TFIIA PF03153.13 KZN87527.1 - 0.0052 16.8 14.9 0.01 15.9 14.9 1.5 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Afaf PF15339.6 KZN87527.1 - 0.48 10.1 3.9 0.19 11.4 0.9 1.8 2 0 0 2 2 2 0 Acrosome formation-associated factor P5-ATPase PF12409.8 KZN87528.1 - 1.9e-39 134.6 0.0 7.9e-39 132.6 0.0 2.1 2 0 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 KZN87528.1 - 8.2e-33 113.4 0.0 1.7e-32 112.4 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KZN87528.1 - 1.6e-14 54.7 0.1 9.5e-06 26.0 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KZN87528.1 - 0.0014 18.3 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KZN87528.1 - 0.0026 17.8 0.0 0.0058 16.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KZN87528.1 - 0.078 12.7 0.0 10 5.7 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase NADH_B2 PF14813.6 KZN87529.1 - 0.011 15.5 0.1 0.012 15.3 0.1 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Pkinase PF00069.25 KZN87530.1 - 5.4e-66 222.7 0.0 6.5e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN87530.1 - 4e-31 108.3 0.0 5.6e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KZN87530.1 - 0.013 14.5 0.0 0.028 13.4 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 KZN87530.1 - 0.037 13.6 0.1 6.5 6.3 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 2-Hacid_dh_C PF02826.19 KZN87531.1 - 9.1e-53 178.3 0.0 1.4e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KZN87531.1 - 2.6e-38 130.7 0.0 3.7e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KZN87531.1 - 0.0001 22.5 1.2 0.00019 21.7 0.2 2.0 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KZN87531.1 - 0.0022 17.6 0.2 0.1 12.2 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 KZN87531.1 - 0.0049 17.0 0.1 0.012 15.6 0.1 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.25 KZN87531.1 - 0.0053 16.5 0.1 0.013 15.2 0.0 1.8 2 0 0 2 2 2 1 ACT domain XdhC_C PF13478.6 KZN87531.1 - 0.096 13.2 0.0 0.4 11.2 0.0 2.1 2 0 0 2 2 2 0 XdhC Rossmann domain 3HCDH_N PF02737.18 KZN87531.1 - 0.19 11.6 0.7 2.3 8.1 0.5 2.5 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Retrotran_gag_3 PF14244.6 KZN87532.1 - 0.0017 18.1 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_2 PF14223.6 KZN87532.1 - 0.088 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Alanine_zipper PF11839.8 KZN87533.1 - 0.025 15.0 0.5 0.025 15.0 0.5 2.5 4 0 0 4 4 4 0 Alanine-zipper, major outer membrane lipoprotein Fez1 PF06818.15 KZN87533.1 - 0.26 11.7 7.2 0.37 11.2 7.2 1.2 1 0 0 1 1 1 0 Fez1 tRNA-synt_2b PF00587.25 KZN87534.1 - 2.4e-37 128.7 0.0 4.7e-37 127.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KZN87534.1 - 3.9e-11 43.1 5.8 3.9e-11 43.1 5.8 2.9 2 1 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Ras PF00071.22 KZN87535.1 - 1.3e-45 154.9 0.1 1.5e-45 154.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KZN87535.1 - 1.4e-16 60.8 0.0 1.9e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KZN87535.1 - 2.3e-08 33.7 0.0 2.6e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KZN87535.1 - 2.5e-05 24.3 0.0 3.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KZN87535.1 - 3.2e-05 23.6 0.6 0.00066 19.3 0.2 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KZN87535.1 - 0.00033 20.1 0.0 0.00044 19.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KZN87535.1 - 0.0015 18.5 0.2 0.28 11.1 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 KZN87535.1 - 0.0062 16.8 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KZN87535.1 - 0.024 14.7 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KZN87535.1 - 0.034 13.7 0.0 0.2 11.2 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B TniB PF05621.11 KZN87535.1 - 0.18 11.2 0.0 0.4 10.1 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein WAPL PF07814.13 KZN87536.1 - 3e-75 253.3 0.3 4e-75 252.9 0.3 1.2 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin UPRTase PF14681.6 KZN87537.1 - 7.3e-78 260.7 0.0 8.4e-78 260.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KZN87537.1 - 0.0029 17.1 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.13 KZN87537.1 - 0.17 11.8 0.2 0.27 11.2 0.2 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Elf1 PF05129.13 KZN87538.1 - 2.6e-29 101.1 0.2 3.3e-29 100.8 0.2 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-Sec23_Sec24 PF04810.15 KZN87538.1 - 0.035 14.1 0.4 1.1 9.4 0.1 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger EST1_DNA_bind PF10373.9 KZN87538.1 - 0.079 12.4 0.0 0.093 12.2 0.0 1.1 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain Ribosomal_S3Ae PF01015.18 KZN87539.1 - 6.3e-88 293.6 3.6 7.8e-88 293.3 3.6 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 KZN87539.1 - 0.016 15.8 0.1 0.16 12.5 0.0 2.2 2 0 0 2 2 2 0 Translation initiation factor SUI1 NEMO PF11577.8 KZN87539.1 - 0.12 12.4 0.3 0.86 9.7 0.0 2.2 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO HABP4_PAI-RBP1 PF04774.15 KZN87540.1 - 0.057 14.3 4.1 0.11 13.4 4.1 1.7 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family Nucleoporin_C PF03177.14 KZN87541.1 - 1.9e-170 568.6 0.0 2.2e-170 568.3 0.0 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 KZN87541.1 - 5.8e-79 265.9 0.0 7.9e-79 265.4 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Acyl_transf_1 PF00698.21 KZN87542.1 - 8.6e-21 74.7 0.0 3.1e-13 49.9 0.0 2.1 2 0 0 2 2 2 2 Acyl transferase domain Phage_portal_2 PF05136.13 KZN87542.1 - 0.061 12.5 0.0 0.093 11.9 0.0 1.2 1 0 0 1 1 1 0 Phage portal protein, lambda family Sedlin_N PF04628.13 KZN87543.1 - 9.7e-13 48.4 0.0 1.3e-12 47.9 0.0 1.3 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Oxidored_q6 PF01058.22 KZN87544.1 - 1.2e-22 80.1 0.0 2e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit AA_permease PF00324.21 KZN87545.1 - 4.2e-101 338.9 31.1 5.2e-101 338.6 31.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KZN87545.1 - 4e-36 124.8 32.8 4.8e-36 124.5 32.8 1.1 1 0 0 1 1 1 1 Amino acid permease RskA PF10099.9 KZN87546.1 - 0.019 15.3 0.8 0.025 14.9 0.8 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF1761 PF08570.10 KZN87547.1 - 2.8e-27 95.4 3.6 3.2e-27 95.3 3.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) Kinocilin PF15033.6 KZN87547.1 - 3.1 7.5 7.5 5.4 6.7 0.2 2.3 1 1 0 2 2 2 0 Kinocilin protein Methyltransf_16 PF10294.9 KZN87548.1 - 1.5e-47 161.6 0.0 1.9e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KZN87548.1 - 0.011 15.6 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KZN87548.1 - 0.043 13.4 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Mpp10 PF04006.12 KZN87549.1 - 9.7e-107 357.9 47.2 1.2e-105 354.3 47.2 2.1 1 1 0 1 1 1 1 Mpp10 protein DUF2756 PF10956.8 KZN87549.1 - 9.9 6.7 8.8 4.4 7.9 3.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2756) adh_short_C2 PF13561.6 KZN87550.1 - 2.7e-59 200.6 0.0 3.3e-59 200.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN87550.1 - 2.1e-47 161.1 0.0 2.6e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN87550.1 - 2.3e-12 47.2 0.0 3.1e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 KZN87550.1 - 0.0005 19.5 0.0 0.023 14.0 0.1 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1776 PF08643.10 KZN87550.1 - 0.005 16.3 0.0 0.0075 15.7 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) PALP PF00291.25 KZN87550.1 - 0.071 12.5 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme AhpC-TSA PF00578.21 KZN87551.1 - 5e-22 78.1 0.0 7.4e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KZN87551.1 - 4e-13 49.3 0.0 5.5e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KZN87551.1 - 0.015 15.4 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme PRELI PF04707.14 KZN87552.1 - 1.7e-42 144.9 0.2 2e-42 144.7 0.2 1.0 1 0 0 1 1 1 1 PRELI-like family BRCA-2_OB3 PF09104.10 KZN87552.1 - 0.055 13.1 0.0 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 CTP_transf_like PF01467.26 KZN87554.1 - 3.9e-23 82.2 0.0 4.6e-20 72.3 0.0 2.8 3 0 0 3 3 3 2 Cytidylyltransferase-like Glutaredoxin PF00462.24 KZN87555.1 - 1.2e-14 54.3 0.0 2.1e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Flavoprotein PF02441.19 KZN87556.1 - 3.1e-32 111.5 0.0 5e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Flavoprotein UbiA PF01040.18 KZN87557.1 - 2.6e-44 151.4 17.1 3.4e-44 151.1 17.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family JmjC PF02373.22 KZN87558.1 - 7.9e-08 32.7 0.2 2.9e-06 27.7 0.2 2.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 KZN87558.1 - 6.1e-06 26.4 12.8 6.1e-06 26.4 12.8 2.9 3 0 0 3 3 3 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 KZN87558.1 - 0.084 12.6 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Coa1 PF08695.10 KZN87560.1 - 3.4e-44 149.4 0.0 4.2e-44 149.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Ribosomal_L3 PF00297.22 KZN87561.1 - 1.1e-17 64.1 6.2 1.2e-15 57.4 2.3 2.2 1 1 1 2 2 2 2 Ribosomal protein L3 DUF1279 PF06916.13 KZN87562.1 - 4.2e-26 91.3 0.0 6e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Zeta_toxin PF06414.12 KZN87562.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Ank_2 PF12796.7 KZN87563.1 - 1.4e-26 92.9 1.5 7e-10 39.4 0.0 5.2 4 2 2 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN87563.1 - 3.7e-21 75.2 5.3 2.2e-08 34.5 0.2 6.5 3 2 4 7 7 7 6 Ankyrin repeats (many copies) SPX PF03105.19 KZN87563.1 - 3.2e-20 73.4 12.3 5.4e-08 33.2 0.4 3.2 1 1 2 3 3 3 3 SPX domain GDPD PF03009.17 KZN87563.1 - 1.8e-16 60.6 0.1 1.9e-15 57.3 0.0 2.1 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_5 PF13857.6 KZN87563.1 - 2.3e-15 56.4 2.9 0.014 15.7 0.3 5.2 2 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN87563.1 - 3.2e-15 54.7 8.5 0.0048 17.3 0.1 7.7 10 0 0 10 10 10 3 Ankyrin repeat Ank PF00023.30 KZN87563.1 - 2.2e-06 27.9 10.2 0.014 15.8 0.3 5.8 6 1 0 6 6 6 2 Ankyrin repeat SKG6 PF08693.10 KZN87564.1 - 2.5e-11 42.8 2.8 2.5e-11 42.8 2.8 3.0 3 0 0 3 3 3 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 KZN87564.1 - 0.00049 19.9 0.2 0.00096 19.0 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) RIFIN PF02009.16 KZN87564.1 - 0.0015 18.5 5.9 0.0044 17.0 5.9 1.7 1 1 0 1 1 1 1 Rifin TFIIA PF03153.13 KZN87564.1 - 0.0034 17.4 2.7 0.0042 17.1 2.7 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Stevor PF17410.2 KZN87564.1 - 0.0057 16.2 0.6 0.0057 16.2 0.6 1.6 2 0 0 2 2 2 1 Subtelomeric Variable Open Reading frame EphA2_TM PF14575.6 KZN87564.1 - 0.15 12.9 0.0 0.48 11.3 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Phage_holin_2_4 PF16082.5 KZN87564.1 - 0.36 10.6 4.8 0.086 12.6 0.4 2.2 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Utp14 PF04615.13 KZN87564.1 - 1.5 7.3 12.3 2.1 6.8 12.3 1.2 1 0 0 1 1 1 0 Utp14 protein Ndc1_Nup PF09531.10 KZN87564.1 - 5.6 5.5 17.3 8.2 5.0 17.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_S64 PF08192.11 KZN87564.1 - 7 5.0 18.4 9 4.6 18.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 OCRE PF17780.1 KZN87565.1 - 0.023 14.7 0.4 0.06 13.4 0.4 1.6 1 0 0 1 1 1 0 OCRE domain ABC_tran PF00005.27 KZN87567.1 - 3.7e-48 163.5 0.6 7.6e-23 81.5 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KZN87567.1 - 5.5e-20 71.2 6.5 5.5e-20 71.2 6.5 3.5 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 KZN87567.1 - 9e-15 55.3 1.7 0.0024 17.8 0.0 4.6 5 0 0 5 5 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KZN87567.1 - 3.6e-09 36.4 1.9 0.17 11.3 0.0 4.6 5 0 0 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KZN87567.1 - 2.8e-07 30.9 0.0 0.00067 19.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KZN87567.1 - 3.2e-07 31.1 13.8 0.017 15.6 0.0 5.0 5 0 0 5 5 5 2 AAA domain AAA_16 PF13191.6 KZN87567.1 - 9.8e-07 29.3 0.7 0.033 14.6 0.2 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 KZN87567.1 - 5.8e-06 26.9 0.3 0.12 12.9 0.1 3.1 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 KZN87567.1 - 9.9e-06 25.6 0.5 0.13 12.4 0.1 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KZN87567.1 - 1.4e-05 24.7 0.2 0.18 11.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KZN87567.1 - 1.5e-05 25.0 0.0 0.082 12.8 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 KZN87567.1 - 2.3e-05 24.2 0.9 0.5 10.1 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KZN87567.1 - 4.7e-05 23.2 0.1 0.0072 16.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 KZN87567.1 - 5.6e-05 23.4 4.5 0.023 15.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 KZN87567.1 - 0.00017 21.8 0.2 0.53 10.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 KZN87567.1 - 0.00041 20.4 1.7 0.69 10.0 0.0 3.9 4 0 0 4 4 4 1 Dynamin family AAA PF00004.29 KZN87567.1 - 0.0013 19.1 0.0 0.58 10.6 0.1 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KZN87567.1 - 0.0014 18.5 16.7 0.19 11.4 0.0 4.7 4 1 0 4 4 4 2 AAA ATPase domain NACHT PF05729.12 KZN87567.1 - 0.0015 18.5 0.1 0.91 9.4 0.0 3.0 4 0 0 4 4 2 1 NACHT domain RNA_helicase PF00910.22 KZN87567.1 - 0.0023 18.3 0.0 1.2 9.6 0.0 2.7 2 0 0 2 2 2 1 RNA helicase ATP-synt_ab PF00006.25 KZN87567.1 - 0.0028 17.4 0.0 0.27 10.8 0.0 2.5 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.12 KZN87567.1 - 0.0045 16.3 0.5 1.5 8.0 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin AAA_14 PF13173.6 KZN87567.1 - 0.0062 16.6 0.0 4.4 7.3 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 KZN87567.1 - 0.0083 15.7 0.3 3 7.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain MeaB PF03308.16 KZN87567.1 - 0.0085 15.1 2.6 2 7.3 0.0 2.7 3 0 0 3 3 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Rad17 PF03215.15 KZN87567.1 - 0.0097 15.8 0.3 0.98 9.3 0.0 3.1 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_5 PF07728.14 KZN87567.1 - 0.015 15.3 0.0 5.4 7.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KZN87567.1 - 0.016 14.7 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 KZN87567.1 - 0.017 15.0 0.1 1.6 8.7 0.1 2.8 2 0 0 2 2 2 0 NTPase Roc PF08477.13 KZN87567.1 - 0.028 14.6 0.0 12 6.1 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 KZN87567.1 - 0.028 14.0 0.5 0.96 9.0 0.0 2.8 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain AAA_17 PF13207.6 KZN87567.1 - 0.039 14.4 0.7 13 6.2 0.0 3.5 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 KZN87567.1 - 0.045 12.9 0.0 6.8 5.8 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain TsaE PF02367.17 KZN87567.1 - 0.065 13.2 0.0 9.4 6.3 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KZN87567.1 - 0.067 12.8 3.2 1 8.9 0.2 3.0 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 KZN87567.1 - 0.084 12.8 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B dNK PF01712.19 KZN87567.1 - 0.084 12.7 0.1 0.96 9.3 0.1 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase PduV-EutP PF10662.9 KZN87567.1 - 0.15 11.8 0.0 22 4.8 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 KZN87567.1 - 0.22 10.9 0.9 1.6 8.1 0.1 2.6 3 0 0 3 3 2 0 ADP-ribosylation factor family PRK PF00485.18 KZN87567.1 - 0.66 9.7 0.0 0.66 9.7 0.0 2.4 4 0 0 4 4 2 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.17 KZN87567.1 - 2.2 8.3 0.0 2.2 8.3 0.0 4.0 6 0 0 6 6 5 0 Helicase HerA, central domain Sugar_tr PF00083.24 KZN87568.1 - 2.3e-104 349.8 19.1 6.1e-104 348.4 19.1 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN87568.1 - 5.2e-31 107.8 60.2 6e-30 104.4 31.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KZN87568.1 - 7.5e-06 24.6 4.9 7.5e-06 24.6 4.9 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) LacY_symp PF01306.19 KZN87568.1 - 0.0005 19.0 8.1 0.0031 16.4 1.5 2.5 2 0 0 2 2 2 2 LacY proton/sugar symporter MFS_3 PF05977.13 KZN87568.1 - 0.0028 16.1 1.6 0.0028 16.1 1.6 2.6 3 0 0 3 3 3 2 Transmembrane secretion effector MFS_1_like PF12832.7 KZN87568.1 - 0.0034 16.3 0.1 0.0034 16.3 0.1 3.5 1 1 2 3 3 3 2 MFS_1 like family WD40 PF00400.32 KZN87569.1 - 6.7e-24 83.7 21.5 1.9e-05 25.3 0.2 7.0 6 2 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN87569.1 - 1.7e-10 41.1 8.4 0.00067 19.9 0.2 4.6 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 KZN87569.1 - 0.00019 21.4 8.3 0.02 14.8 0.2 2.5 1 1 0 2 2 2 2 Transcription factor IIIC subunit delta N-term DUF3131 PF11329.8 KZN87570.1 - 0.071 12.2 1.6 0.13 11.3 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3131) DUF3060 PF11259.8 KZN87571.1 - 0.038 13.7 0.2 6.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3060) Pec_lyase_C PF00544.19 KZN87572.1 - 1.4e-13 51.0 6.1 1.5e-12 47.5 6.1 2.1 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KZN87572.1 - 0.0058 16.5 14.8 0.45 10.4 4.4 2.4 1 1 1 2 2 2 2 Right handed beta helix region Myb_DNA-bind_6 PF13921.6 KZN87576.1 - 0.00017 21.8 0.1 0.00033 20.9 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KZN87576.1 - 0.00087 19.4 0.1 0.0015 18.7 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Zn_clus PF00172.18 KZN87577.1 - 2.3e-06 27.6 9.4 4.4e-06 26.7 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_5 PF13857.6 KZN87579.1 - 0.013 15.8 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (many copies) NleF_casp_inhib PF16809.5 KZN87579.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 NleF caspase inhibitor Pkinase_Tyr PF07714.17 KZN87580.1 - 0.0012 18.2 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KZN87580.1 - 0.03 13.7 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Catalase-rel PF06628.12 KZN87582.1 - 8.4e-06 25.9 0.0 4.4e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Catalase-related immune-responsive F-box-like PF12937.7 KZN87582.1 - 3.6e-05 23.6 0.1 9.1e-05 22.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN87582.1 - 0.0069 16.2 2.9 0.016 15.0 1.0 2.4 2 0 0 2 2 2 1 F-box domain Pectate_lyase_3 PF12708.7 KZN87584.1 - 5.1e-100 333.7 9.4 1.3e-84 283.4 4.6 2.8 2 0 0 2 2 2 2 Pectate lyase superfamily protein LysM PF01476.20 KZN87584.1 - 1.8e-11 43.9 0.1 0.00067 19.7 0.0 3.8 3 0 0 3 3 3 3 LysM domain End_N_terminal PF12218.8 KZN87584.1 - 4.8e-07 29.4 2.4 0.013 15.2 0.1 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Glyco_hydro_18 PF00704.28 KZN87585.1 - 7.3e-65 219.7 0.3 1.1e-64 219.2 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KZN87585.1 - 3.7e-09 36.9 9.4 3.7e-09 36.9 9.4 5.6 7 0 0 7 7 7 2 Chitin recognition protein HEPN_Swt1 PF18731.1 KZN87585.1 - 0.12 12.7 0.2 0.28 11.5 0.2 1.6 1 0 0 1 1 1 0 Swt1-like HEPN MatE PF01554.18 KZN87587.1 - 0.00018 21.2 14.5 0.00029 20.5 0.6 3.7 4 0 0 4 4 4 3 MatE Polysacc_synt_C PF14667.6 KZN87587.1 - 0.0098 16.0 0.9 0.0098 16.0 0.9 3.0 2 1 1 3 3 3 1 Polysaccharide biosynthesis C-terminal domain TPR_16 PF13432.6 KZN87588.1 - 0.00016 22.3 4.7 0.00016 22.3 4.7 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KZN87588.1 - 0.00063 19.5 2.1 0.08 12.8 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KZN87588.1 - 0.01 15.9 7.3 0.43 10.8 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KZN87588.1 - 0.014 15.9 2.3 1.7 9.2 0.4 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat Egh16-like PF11327.8 KZN87591.1 - 3.4e-41 141.7 3.5 5.1e-41 141.1 3.5 1.3 1 1 0 1 1 1 1 Egh16-like virulence factor Scytalone_dh PF02982.14 KZN87592.1 - 1.4e-17 63.9 0.1 1.8e-17 63.6 0.1 1.1 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 KZN87592.1 - 5.9e-11 42.6 0.3 7.4e-11 42.3 0.3 1.1 1 0 0 1 1 1 1 SnoaL-like domain YfkB PF08756.10 KZN87592.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.5 1 1 0 1 1 1 0 YfkB-like domain CitX PF03802.14 KZN87595.1 - 0.028 14.2 0.1 0.032 14.0 0.1 1.1 1 0 0 1 1 1 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase PSDC PF12588.8 KZN87596.1 - 5.8 6.9 6.4 2.6e+02 1.6 6.4 2.5 1 1 0 1 1 1 0 Phophatidylserine decarboxylase BNIP3 PF06553.12 KZN87597.1 - 0.091 12.4 4.0 0.13 12.0 4.0 1.3 1 0 0 1 1 1 0 BNIP3 Methyltrans_Mon PF14314.6 KZN87597.1 - 0.11 10.5 0.2 0.14 10.2 0.2 1.0 1 0 0 1 1 1 0 Virus-capping methyltransferase Get5_C PF18514.1 KZN87598.1 - 0.091 12.5 0.1 0.35 10.6 0.0 2.0 2 0 0 2 2 2 0 Get5 C-terminal domain RIC3 PF15361.6 KZN87598.1 - 1.5 9.2 3.3 2.4 8.5 3.3 1.3 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF3723 PF12520.8 KZN87601.1 - 5.9e-69 233.1 0.0 4.5e-62 210.4 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF3723) Metaviral_G PF09595.10 KZN87601.1 - 0.043 13.9 0.1 0.071 13.2 0.1 1.2 1 0 0 1 1 1 0 Metaviral_G glycoprotein SlyX PF04102.12 KZN87604.1 - 0.051 14.2 0.7 0.1 13.3 0.0 1.7 2 0 0 2 2 2 0 SlyX SRF-TF PF00319.18 KZN87605.1 - 0.00088 18.7 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Prok-JAB PF14464.6 KZN87605.1 - 0.0019 18.0 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain BAR_2 PF10455.9 KZN87606.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking EF-hand_14 PF17959.1 KZN87607.1 - 0.15 12.4 0.1 1.4 9.3 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain Patatin PF01734.22 KZN87608.1 - 9.8e-21 74.9 1.3 1.8e-20 74.0 0.3 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase zf-C3HC4_3 PF13920.6 KZN87608.1 - 2.5e-05 24.1 6.1 6.8e-05 22.6 6.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KZN87608.1 - 0.0011 18.8 5.8 0.0039 17.0 5.8 2.0 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KZN87608.1 - 0.0013 18.5 5.2 0.0055 16.6 5.3 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KZN87608.1 - 0.0084 16.1 7.2 0.027 14.4 7.2 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KZN87608.1 - 0.15 12.4 8.7 0.53 10.7 8.7 2.1 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 KZN87608.1 - 0.98 9.3 8.0 1.1 9.2 4.1 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KZN87608.1 - 4.6 7.4 11.1 1.8 8.6 4.9 2.9 2 0 0 2 2 2 0 RING-type zinc-finger Phage_holin_3_3 PF16083.5 KZN87609.1 - 0.14 12.3 2.9 0.95 9.6 3.3 2.1 1 1 1 2 2 2 0 LydA holin phage, holin superfamily III Glyco_hydro_61 PF03443.14 KZN87610.1 - 0.0043 17.0 0.0 0.0068 16.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4625 PF15418.6 KZN87610.1 - 0.012 15.9 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) FlgN PF05130.12 KZN87612.1 - 0.028 14.9 3.5 0.037 14.5 3.5 1.1 1 0 0 1 1 1 0 FlgN protein MAP7 PF05672.11 KZN87612.1 - 0.03 14.0 1.8 0.04 13.6 1.8 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Nup192 PF11894.8 KZN87612.1 - 0.11 9.6 0.7 0.13 9.4 0.7 1.0 1 0 0 1 1 1 0 Nuclear pore complex scaffold, nucleoporins 186/192/205 Phage_lysis PF03245.13 KZN87613.1 - 0.017 15.2 0.4 0.019 15.1 0.4 1.0 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Helo_like_N PF17111.5 KZN87615.1 - 6.2e-78 261.0 6.9 2.2e-76 255.9 6.0 2.1 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins TMF_DNA_bd PF12329.8 KZN87615.1 - 0.0011 19.0 2.8 0.0011 18.9 0.4 2.2 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding SesA PF17107.5 KZN87615.1 - 0.0023 18.1 0.5 0.0085 16.3 0.1 2.1 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Spc7 PF08317.11 KZN87615.1 - 0.0034 16.3 7.3 0.12 11.3 0.2 3.0 2 1 1 3 3 3 2 Spc7 kinetochore protein Rx_N PF18052.1 KZN87615.1 - 0.0082 16.4 0.3 0.048 13.9 0.2 2.5 2 0 0 2 2 2 1 Rx N-terminal domain NPV_P10 PF05531.12 KZN87615.1 - 0.036 14.5 0.6 0.12 12.8 0.6 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein APG6_N PF17675.1 KZN87615.1 - 0.057 13.9 0.6 0.057 13.9 0.6 3.3 3 1 0 3 3 3 0 Apg6 coiled-coil region DASH_Duo1 PF08651.10 KZN87615.1 - 0.095 12.5 1.3 0.68 9.7 0.1 2.9 3 0 0 3 3 3 0 DASH complex subunit Duo1 ATG16 PF08614.11 KZN87615.1 - 0.16 12.1 5.4 0.26 11.5 0.1 2.8 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.12 KZN87615.1 - 0.18 11.9 4.4 1.2 9.2 0.2 3.1 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 KZN87615.1 - 0.26 11.3 3.8 4.9 7.2 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) GAS PF13851.6 KZN87615.1 - 0.58 9.5 4.1 0.81 9.0 0.2 2.9 4 0 0 4 4 4 0 Growth-arrest specific micro-tubule binding Med9 PF07544.13 KZN87615.1 - 0.59 10.3 6.6 3.2 7.9 0.4 3.2 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 UCR_Fe-S_N PF10399.9 KZN87615.1 - 1.2 8.6 3.3 7.3 6.0 0.1 2.6 3 0 0 3 3 3 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Spectrin PF00435.21 KZN87615.1 - 2.6 8.6 5.7 3.3 8.3 0.9 3.2 2 1 2 4 4 4 0 Spectrin repeat TPR_MLP1_2 PF07926.12 KZN87615.1 - 3.9 7.5 10.7 4.1 7.5 0.6 3.5 4 0 0 4 4 4 0 TPR/MLP1/MLP2-like protein JIP_LZII PF16471.5 KZN87615.1 - 5.9 7.1 12.5 1.9 8.7 0.5 3.7 4 0 0 4 4 4 0 JNK-interacting protein leucine zipper II Fib_alpha PF08702.10 KZN87615.1 - 6.2 7.0 8.0 1.4 9.0 0.4 2.8 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family HIP1_clath_bdg PF16515.5 KZN87615.1 - 9.4 6.9 10.1 11 6.7 0.8 3.2 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Retrotran_gag_2 PF14223.6 KZN87616.1 - 1.8e-12 47.1 0.0 2.5e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-C2H2_10 PF16588.5 KZN87616.1 - 0.0046 16.6 2.3 0.0081 15.9 2.3 1.4 1 0 0 1 1 1 1 C2H2 zinc-finger zf-CCHC PF00098.23 KZN87616.1 - 0.12 12.5 2.3 0.28 11.3 2.3 1.6 1 0 0 1 1 1 0 Zinc knuckle RNase_H PF00075.24 KZN87618.1 - 0.036 14.2 0.8 0.15 12.2 0.0 2.4 3 0 0 3 3 3 0 RNase H SANT_DAMP1_like PF16282.5 KZN87619.1 - 0.021 15.0 0.4 0.031 14.5 0.4 1.2 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 PNMA PF14893.6 KZN87620.1 - 0.0064 15.9 1.1 0.0082 15.6 1.1 1.1 1 0 0 1 1 1 1 PNMA SEEEED PF14797.6 KZN87620.1 - 0.078 13.1 15.1 0.12 12.5 15.1 1.3 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex Tmemb_9 PF05434.11 KZN87620.1 - 0.44 10.4 2.1 0.67 9.8 0.1 2.0 1 1 1 2 2 2 0 TMEM9 Ank_2 PF12796.7 KZN87621.1 - 2.5e-59 197.8 13.6 1.3e-15 57.7 0.0 6.9 2 1 7 9 9 9 8 Ankyrin repeats (3 copies) Ank PF00023.30 KZN87621.1 - 5.6e-45 149.9 13.9 1.7e-06 28.2 0.0 13.1 12 1 0 12 12 12 7 Ankyrin repeat Ank_4 PF13637.6 KZN87621.1 - 4.1e-44 148.4 6.7 7.5e-07 29.6 0.0 9.4 2 2 7 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN87621.1 - 8e-38 124.1 3.1 0.00049 20.3 0.0 13.0 13 1 0 13 13 13 8 Ankyrin repeat Ank_5 PF13857.6 KZN87621.1 - 1.6e-25 88.8 6.7 6.2e-05 23.2 0.0 8.1 5 2 6 11 11 11 8 Ankyrin repeats (many copies) F-box-like PF12937.7 KZN87621.1 - 2.4e-05 24.1 1.0 3.8e-05 23.5 0.1 1.8 2 0 0 2 2 2 1 F-box-like BAT PF15915.5 KZN87621.1 - 0.23 11.3 0.6 2.2 8.1 0.1 2.6 2 1 1 3 3 3 0 GAF and HTH_10 associated domain RlmM_FDX PF18125.1 KZN87623.1 - 0.026 15.0 0.0 0.034 14.6 0.0 1.2 1 0 0 1 1 1 0 RlmM ferredoxin-like domain ZapB PF06005.12 KZN87624.1 - 0.44 11.0 3.4 1 9.9 3.4 1.6 1 1 0 1 1 1 0 Cell division protein ZapB AAA PF00004.29 KZN87627.1 - 3.8e-18 66.2 0.0 7.7e-17 62.0 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KZN87627.1 - 2.6e-06 27.9 1.6 0.00027 21.3 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.6 KZN87627.1 - 0.02 15.3 0.1 0.17 12.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 KZN87627.1 - 0.035 14.4 2.7 6 7.1 0.0 3.4 2 1 1 3 3 3 0 AAA domain AAA_5 PF07728.14 KZN87627.1 - 0.039 13.9 0.0 0.26 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KZN87627.1 - 0.11 12.2 0.0 9 6.0 0.0 2.6 3 0 0 3 3 3 0 AAA domain PdaC PF13739.6 KZN87627.1 - 1.5 9.9 3.5 7.6 7.6 1.5 2.5 2 0 0 2 2 2 0 Deacetylase PdaC HSDR_N_2 PF13588.6 KZN87628.1 - 0.0049 16.9 0.1 0.14 12.2 0.0 2.6 3 0 0 3 3 3 1 Type I restriction enzyme R protein N terminus (HSDR_N) Radial_spoke_3 PF06098.11 KZN87628.1 - 0.0084 15.4 13.9 0.012 15.0 12.1 2.2 2 0 0 2 2 2 1 Radial spoke protein 3 DDRGK PF09756.9 KZN87628.1 - 0.013 15.1 16.5 0.03 13.9 16.5 1.5 1 0 0 1 1 1 0 DDRGK domain MIF4G_like_2 PF09090.11 KZN87628.1 - 0.37 10.2 5.9 0.62 9.5 5.9 1.3 1 0 0 1 1 1 0 MIF4G like NARP1 PF12569.8 KZN87628.1 - 1.7 7.5 11.1 2.9 6.7 11.1 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 ORC6 PF05460.13 KZN87629.1 - 0.072 12.4 8.8 0.097 11.9 8.8 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Helitron_like_N PF14214.6 KZN87630.1 - 6.7e-32 111.3 0.0 1.2e-31 110.5 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 KZN87630.1 - 5e-08 32.5 0.8 3.3e-06 26.5 0.8 2.2 1 1 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.6 KZN87630.1 - 2e-05 25.0 0.0 4.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KZN87630.1 - 0.00036 20.3 0.1 0.0012 18.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain Rhodanese_C PF12368.8 KZN87630.1 - 2.5 8.6 10.4 7.7 7.0 1.4 3.1 2 0 0 2 2 2 0 Rhodanase C-terminal Stb3 PF10330.9 KZN87631.1 - 8.5e-33 112.3 0.0 1.4e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein Grg1 PF11034.8 KZN87633.1 - 7.8e-32 109.3 16.2 9e-32 109.1 16.2 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 Grg1 PF11034.8 KZN87634.1 - 4.8e-16 58.7 15.3 9e-15 54.7 14.2 2.0 1 1 0 1 1 1 1 Glucose-repressible protein Grg1 GerPC PF10737.9 KZN87635.1 - 0.28 11.2 13.5 0.47 10.5 13.5 1.3 1 1 0 1 1 1 0 Spore germination protein GerPC DUF1943 PF09172.11 KZN87635.1 - 0.45 9.7 15.6 19 4.4 15.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1943) TryThrA_C PF12319.8 KZN87635.1 - 2.5 7.5 13.6 0.91 9.0 3.5 2.0 1 1 1 2 2 2 0 Tryptophan-Threonine-rich plasmodium antigen C terminal MatP PF06303.12 KZN87635.1 - 6.6 7.4 11.5 38 4.9 4.8 3.0 1 1 1 2 2 2 0 MatP N-terminal domain Secretin_N_2 PF07655.13 KZN87635.1 - 7.7 7.1 12.3 2 9.0 6.2 2.1 1 1 1 2 2 2 0 Secretin N-terminal domain MARVEL PF01284.23 KZN87636.1 - 6e-13 49.0 7.9 7.7e-13 48.7 7.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF2615 PF11027.8 KZN87636.1 - 0.0062 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) DUF202 PF02656.15 KZN87636.1 - 0.042 14.3 1.8 4.2 7.9 1.8 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Ndc1_Nup PF09531.10 KZN87636.1 - 0.26 9.9 4.3 0.48 9.0 4.1 1.6 1 1 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hydrolase_like PF13242.6 KZN87637.1 - 0.00054 20.0 0.0 0.00083 19.4 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 KZN87637.1 - 0.04 14.0 0.0 0.052 13.6 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase bZIP_1 PF00170.21 KZN87638.1 - 2e-06 27.8 9.5 6.1e-06 26.2 9.5 1.9 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KZN87638.1 - 0.00027 20.9 11.5 0.0016 18.5 11.2 2.3 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KZN87638.1 - 0.0047 17.4 7.3 0.0047 17.4 7.3 2.0 2 0 0 2 2 2 1 bZIP Maf transcription factor CDC45 PF02724.14 KZN87638.1 - 0.068 11.5 4.4 0.083 11.2 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein VIR_N PF15912.5 KZN87638.1 - 0.4 10.2 4.5 0.58 9.7 4.5 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal RhoGEF PF00621.20 KZN87639.1 - 0.011 15.9 0.0 0.017 15.4 0.0 1.3 1 0 0 1 1 1 0 RhoGEF domain RhoGEF PF00621.20 KZN87640.1 - 1.1e-13 51.8 0.0 1.6e-12 48.0 0.0 2.1 2 0 0 2 2 2 1 RhoGEF domain DUF3383 PF11863.8 KZN87641.1 - 0.037 13.0 0.2 0.047 12.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3383) zf-BED PF02892.15 KZN87643.1 - 0.089 12.8 1.7 0.18 11.9 1.7 1.6 1 1 0 1 1 1 0 BED zinc finger MFS_1 PF07690.16 KZN87644.1 - 4e-38 131.2 42.3 4e-38 131.2 42.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN87644.1 - 1.5e-09 37.2 16.2 1.5e-09 37.2 16.2 2.3 2 1 1 3 3 3 1 Sugar (and other) transporter Spc7_N PF15402.6 KZN87644.1 - 0.081 11.2 0.1 0.11 10.7 0.1 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 RINGv PF12906.7 KZN87645.1 - 0.11 12.7 3.4 0.16 12.1 3.4 1.3 1 0 0 1 1 1 0 RING-variant domain zf-RING_2 PF13639.6 KZN87645.1 - 0.32 11.4 3.5 0.48 10.8 3.5 1.3 1 0 0 1 1 1 0 Ring finger domain Ank_2 PF12796.7 KZN87646.1 - 2.4e-52 175.5 6.8 6.6e-13 49.1 0.1 5.5 3 3 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KZN87646.1 - 1.3e-41 135.8 7.4 0.00057 20.1 0.1 11.2 11 0 0 11 11 11 11 Ankyrin repeat Ank_5 PF13857.6 KZN87646.1 - 1.8e-39 133.3 12.2 2.1e-08 34.3 0.0 9.4 3 3 6 9 9 9 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 KZN87646.1 - 3.1e-39 132.8 11.5 1.6e-08 34.9 0.1 7.2 4 3 4 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 KZN87646.1 - 2e-32 110.2 12.7 8.5e-06 26.0 0.0 10.1 10 0 0 10 10 10 7 Ankyrin repeat F-box-like PF12937.7 KZN87646.1 - 8.9e-06 25.5 0.3 1.9e-05 24.5 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN87646.1 - 0.0029 17.5 0.2 0.0029 17.5 0.2 2.1 2 0 0 2 2 2 1 F-box domain gag_pre-integrs PF13976.6 KZN87647.1 - 0.0075 16.1 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain Ank_5 PF13857.6 KZN87648.1 - 3.7e-54 180.1 4.0 2.8e-11 43.4 0.0 7.1 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 KZN87648.1 - 5.2e-54 180.8 5.0 1.2e-15 57.9 0.2 4.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN87648.1 - 1.4e-45 153.1 0.7 4.5e-08 33.5 0.0 6.0 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN87648.1 - 7.5e-43 139.6 0.0 4.2e-05 23.6 0.0 9.5 9 0 0 9 9 9 8 Ankyrin repeat Ank PF00023.30 KZN87648.1 - 9.8e-38 127.0 5.9 8.8e-05 22.8 0.0 9.4 10 0 0 10 10 10 8 Ankyrin repeat DUF3151 PF11349.8 KZN87648.1 - 0.0049 17.0 1.6 37 4.4 0.0 4.5 2 1 3 5 5 5 0 Protein of unknown function (DUF3151) DUF3881 PF12997.7 KZN87648.1 - 0.0053 16.0 0.8 2.1 7.5 0.0 3.5 2 1 2 4 4 4 1 Domain of unknown function, E. rectale Gene description (DUF3881) DUF4650 PF15509.6 KZN87648.1 - 0.0087 15.4 1.6 1.8 7.8 0.1 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4650) LLGL PF08366.13 KZN87648.1 - 0.02 15.2 0.1 52 4.2 0.0 3.3 3 0 0 3 3 3 0 LLGL2 DUF1934 PF09148.10 KZN87648.1 - 0.12 12.4 0.3 14 5.7 0.0 3.1 1 1 0 3 3 3 0 Domain of unknown function (DUF1934) DUF4727 PF15856.5 KZN87648.1 - 0.22 11.1 0.4 30 4.1 0.0 3.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4727) Cytochrom_C552 PF02335.15 KZN87648.1 - 0.23 10.4 0.0 41 2.9 0.0 2.8 1 1 2 3 3 3 0 Cytochrome c552 HNH_repeat PF18780.1 KZN87648.1 - 0.81 9.6 5.2 32 4.5 0.0 4.1 5 0 0 5 5 5 0 Homing endonuclease repeat Pyr_redox_3 PF13738.6 KZN87650.1 - 2.5e-23 82.8 0.1 1e-22 80.8 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KZN87650.1 - 1.5e-15 57.2 0.2 2.3e-13 50.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KZN87650.1 - 2.1e-13 50.2 0.1 2.2e-10 40.2 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KZN87650.1 - 9.7e-12 44.1 0.2 2.3e-10 39.5 0.1 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Shikimate_DH PF01488.20 KZN87650.1 - 2.3e-07 30.9 0.0 0.00016 21.8 0.0 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KZN87650.1 - 2.5e-07 31.1 1.1 0.017 15.6 0.2 4.1 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KZN87650.1 - 2.2e-05 23.9 0.1 0.14 11.5 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 KZN87650.1 - 5.4e-05 23.3 0.3 0.0032 17.7 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KZN87650.1 - 0.00025 21.0 0.9 2.1 8.3 0.1 4.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KZN87650.1 - 0.00029 20.2 2.6 0.0063 15.8 0.3 2.6 2 1 1 3 3 3 1 FAD binding domain F420_oxidored PF03807.17 KZN87650.1 - 0.00061 20.3 0.0 0.48 11.1 0.0 3.4 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent XdhC_C PF13478.6 KZN87650.1 - 0.0008 19.9 0.0 0.0041 17.6 0.0 2.1 2 0 0 2 2 2 1 XdhC Rossmann domain NAD_binding_7 PF13241.6 KZN87650.1 - 0.00094 19.6 0.0 0.18 12.2 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 KZN87650.1 - 0.0021 17.2 0.2 0.013 14.6 0.1 2.2 2 1 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 KZN87650.1 - 0.0035 16.7 0.0 1.4 8.1 0.1 3.0 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase DAO PF01266.24 KZN87650.1 - 0.0037 16.9 2.7 0.38 10.3 0.1 3.5 2 1 0 4 4 4 1 FAD dependent oxidoreductase IlvN PF07991.12 KZN87650.1 - 0.0039 16.8 0.1 1.8 8.1 0.0 2.3 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 KZN87650.1 - 0.0054 16.6 0.1 0.14 12.0 0.1 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 KZN87650.1 - 0.009 15.1 0.3 0.088 11.8 0.0 2.8 3 1 0 3 3 3 1 Lycopene cyclase protein GIDA PF01134.22 KZN87650.1 - 0.0092 15.1 0.5 3.7 6.5 0.2 2.4 2 1 0 2 2 2 2 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KZN87650.1 - 0.017 14.4 0.0 0.65 9.3 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KZN87650.1 - 0.018 15.3 0.1 0.83 9.9 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain ThiF PF00899.21 KZN87650.1 - 0.018 14.4 1.0 0.37 10.1 0.0 2.3 2 0 0 2 2 2 0 ThiF family HI0933_like PF03486.14 KZN87650.1 - 0.13 10.9 0.1 0.41 9.3 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Zn_clus PF00172.18 KZN87652.1 - 2.8e-07 30.6 7.4 5.6e-07 29.6 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KZN87652.1 - 3e-07 29.6 1.4 4.6e-07 29.0 0.4 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Caps_synth PF05704.12 KZN87653.1 - 2e-08 34.0 0.0 6.7e-08 32.3 0.0 1.9 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 KZN87653.1 - 3.1e-05 24.5 0.0 9e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif 4HBT_3 PF13622.6 KZN87654.1 - 4.4e-24 86.1 0.0 5.4e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KZN87654.1 - 0.093 13.1 0.0 3.3 8.1 0.0 2.3 2 1 0 2 2 2 0 Thioesterase superfamily AAA PF00004.29 KZN87655.1 - 6.7e-17 62.2 0.0 1.5e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KZN87655.1 - 4.6e-05 23.9 0.1 0.00085 19.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.6 KZN87655.1 - 0.0013 19.1 0.0 0.079 13.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 KZN87655.1 - 0.0059 16.6 0.0 0.12 12.4 0.0 2.6 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KZN87655.1 - 0.029 14.6 2.0 7.7 6.8 0.0 3.2 2 1 1 3 3 3 0 AAA domain AAA_24 PF13479.6 KZN87655.1 - 0.091 12.5 0.0 7.1 6.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain Radial_spoke_3 PF06098.11 KZN87656.1 - 0.001 18.4 11.0 0.0033 16.8 9.3 2.2 2 0 0 2 2 2 1 Radial spoke protein 3 HSDR_N_2 PF13588.6 KZN87656.1 - 0.0037 17.2 0.1 0.038 14.0 0.0 2.3 2 0 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) Casc1_N PF15927.5 KZN87656.1 - 7.4 6.2 20.0 13 5.4 20.0 1.4 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Dimer_Tnp_hAT PF05699.14 KZN87658.1 - 1.6e-10 40.6 0.0 2.5e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region CAF1A PF12253.8 KZN87658.1 - 0.54 10.5 7.4 0.92 9.7 7.4 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A FUSC PF04632.12 KZN87662.1 - 0.044 12.3 3.6 0.053 12.1 3.6 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3723 PF12520.8 KZN87665.1 - 8.2e-12 44.6 0.4 2.5e-11 43.0 0.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3723) DUF3723 PF12520.8 KZN87666.1 - 1.3e-35 123.0 0.1 1.7e-28 99.6 0.0 2.5 3 1 0 3 3 3 2 Protein of unknown function (DUF3723) Metaviral_G PF09595.10 KZN87666.1 - 0.027 14.6 0.1 0.047 13.8 0.1 1.2 1 0 0 1 1 1 0 Metaviral_G glycoprotein SRF-TF PF00319.18 KZN87670.1 - 0.00087 18.7 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Prok-JAB PF14464.6 KZN87670.1 - 0.0013 18.4 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Patatin PF01734.22 KZN87673.1 - 6.4e-21 75.5 0.9 1.6e-20 74.2 0.3 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase zf-C3HC4_3 PF13920.6 KZN87673.1 - 3.6e-05 23.5 6.2 0.0001 22.1 6.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KZN87673.1 - 0.0017 18.2 7.0 0.0073 16.2 7.0 2.1 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KZN87673.1 - 0.009 15.9 8.4 0.029 14.2 8.4 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KZN87673.1 - 0.01 15.8 7.4 0.031 14.2 7.4 1.9 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 KZN87673.1 - 0.17 12.3 9.2 0.59 10.5 9.2 2.1 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 KZN87673.1 - 0.59 10.0 7.2 0.75 9.7 3.7 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KZN87673.1 - 4.4 7.4 11.1 1.8 8.6 4.9 2.9 2 0 0 2 2 2 0 RING-type zinc-finger Phage_holin_3_3 PF16083.5 KZN87674.1 - 0.65 10.2 5.0 1.7 8.8 3.5 2.4 2 1 1 3 3 3 0 LydA holin phage, holin superfamily III Pkinase PF00069.25 KZN87675.1 - 1.2e-05 24.8 0.0 1.5e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN87675.1 - 0.024 13.9 0.0 0.029 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase PHINT_rpt PF14882.6 KZN87678.1 - 0.14 12.5 0.0 0.36 11.1 0.0 1.7 2 0 0 2 2 2 0 Phage-integrase repeat unit Ank_2 PF12796.7 KZN87680.1 - 4.5e-44 148.9 4.8 4e-11 43.4 0.0 6.0 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KZN87680.1 - 2.7e-36 119.5 10.2 0.00028 21.1 0.0 11.4 11 0 0 11 11 11 9 Ankyrin repeat Ank_4 PF13637.6 KZN87680.1 - 3.4e-35 120.0 12.4 2.9e-06 27.7 0.0 7.7 3 3 6 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KZN87680.1 - 5.7e-35 118.9 11.0 1.7e-08 34.6 0.1 9.2 4 3 5 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 KZN87680.1 - 5.1e-27 93.1 19.5 9.7e-06 25.8 0.0 9.7 10 0 0 10 10 10 7 Ankyrin repeat F-box-like PF12937.7 KZN87680.1 - 0.00024 20.9 0.2 0.00045 20.1 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN87680.1 - 0.032 14.1 0.1 0.069 13.0 0.1 1.6 1 0 0 1 1 1 0 F-box domain DUF3330 PF11809.8 KZN87681.1 - 0.0028 17.7 0.1 0.0091 16.0 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3330) zf-RING_2 PF13639.6 KZN87681.1 - 0.0067 16.7 8.8 0.015 15.7 8.8 1.6 1 0 0 1 1 1 1 Ring finger domain Zn_ribbon_17 PF17120.5 KZN87681.1 - 0.38 10.4 7.4 0.93 9.2 7.4 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Ank_2 PF12796.7 KZN87682.1 - 1.1e-10 41.9 0.0 1.9e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN87682.1 - 7.4e-08 32.8 0.0 0.00095 19.7 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN87682.1 - 2.1e-07 30.7 0.0 0.0013 19.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KZN87682.1 - 4e-07 30.2 0.0 0.00064 20.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KZN87682.1 - 1.5e-06 28.3 0.0 9.7e-06 25.8 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Phage_holin_3_5 PF16085.5 KZN87686.1 - 0.083 13.0 0.4 0.11 12.6 0.4 1.2 1 0 0 1 1 1 0 Bacteriophage holin Hol, superfamily III Apolipoprotein PF01442.18 KZN87687.1 - 0.035 14.0 0.4 0.071 13.0 0.4 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Kdo PF06293.14 KZN87688.1 - 8.7e-05 22.0 0.1 0.00013 21.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KZN87688.1 - 0.0024 17.5 0.0 0.0039 16.8 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KZN87688.1 - 0.023 14.6 0.2 0.097 12.6 0.2 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KZN87688.1 - 0.028 13.8 0.0 0.039 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain WaaY PF06176.11 KZN87688.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) DUF3330 PF11809.8 KZN87689.1 - 0.003 17.6 0.1 0.0072 16.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3330) zf-RING_2 PF13639.6 KZN87689.1 - 0.0083 16.4 9.0 0.015 15.7 9.0 1.4 1 0 0 1 1 1 1 Ring finger domain RINGv PF12906.7 KZN87689.1 - 0.11 12.6 9.6 0.22 11.7 9.6 1.5 1 0 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 KZN87689.1 - 0.53 9.9 7.9 1.1 9.0 7.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF2745 PF10922.8 KZN87690.1 - 0.093 13.0 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2745) CitX PF03802.14 KZN87692.1 - 0.019 14.8 0.1 0.021 14.6 0.1 1.1 1 0 0 1 1 1 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase DUF1943 PF09172.11 KZN87693.1 - 0.0002 20.7 12.5 0.0093 15.2 4.7 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF1943) GerPC PF10737.9 KZN87693.1 - 0.0041 17.2 9.0 0.0074 16.4 9.0 1.5 1 1 0 1 1 1 1 Spore germination protein GerPC TryThrA_C PF12319.8 KZN87693.1 - 0.074 12.5 9.6 0.53 9.7 9.6 1.9 1 1 0 1 1 1 0 Tryptophan-Threonine-rich plasmodium antigen C terminal PIN_5 PF08745.11 KZN87693.1 - 0.11 11.9 4.4 0.38 10.1 4.4 1.7 1 1 0 1 1 1 0 PINc domain ribonuclease MatP PF06303.12 KZN87693.1 - 0.16 12.5 8.6 3e+02 2.0 8.6 3.2 1 1 0 1 1 1 0 MatP N-terminal domain IAT_beta PF11924.8 KZN87693.1 - 0.33 10.3 4.8 20 4.5 4.8 2.3 1 1 0 1 1 1 0 Inverse autotransporter, beta-domain Methyltrans_Mon PF14314.6 KZN87694.1 - 0.039 12.0 0.4 0.05 11.6 0.4 1.1 1 0 0 1 1 1 0 Virus-capping methyltransferase DUF4407 PF14362.6 KZN87694.1 - 0.82 9.0 4.4 0.97 8.7 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) KAR9 PF08580.10 KZN87695.1 - 0.046 12.3 0.1 0.046 12.3 0.1 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Get5_C PF18514.1 KZN87695.1 - 0.091 12.5 0.1 0.35 10.6 0.0 2.0 2 0 0 2 2 2 0 Get5 C-terminal domain DUF1129 PF06570.11 KZN87698.1 - 0.3 10.5 3.1 0.49 9.9 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF3723 PF12520.8 KZN87699.1 - 7.6e-69 232.7 0.0 4.7e-62 210.3 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF3723) DUF1180 PF06679.12 KZN87700.1 - 5.9 7.3 7.6 8.5 6.8 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Patatin PF01734.22 KZN87704.1 - 4.5e-22 79.2 0.4 1.2e-21 77.8 0.4 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase Prok-RING_4 PF14447.6 KZN87704.1 - 0.099 12.5 10.7 0.42 10.5 10.7 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KZN87704.1 - 0.11 12.4 11.5 0.33 10.9 11.5 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KZN87704.1 - 0.12 12.3 10.7 0.37 10.8 10.7 1.9 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 KZN87704.1 - 1.3 9.5 12.2 4.4 7.7 12.2 2.1 1 0 0 1 1 1 0 Ring finger domain rve PF00665.26 KZN87705.1 - 1e-18 67.7 0.0 2e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 KZN87705.1 - 1.5e-12 47.4 0.0 2.6e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KZN87705.1 - 4.5e-09 35.8 1.6 5.4e-09 35.5 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 KZN87705.1 - 7.5e-07 28.9 0.0 1.9e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 KZN87705.1 - 0.00011 22.0 0.0 0.00023 20.9 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-C2H2_10 PF16588.5 KZN87705.1 - 0.015 15.0 2.3 0.031 14.0 2.3 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger rve_3 PF13683.6 KZN87705.1 - 0.037 13.8 0.1 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 Integrase core domain zf-CCHC PF00098.23 KZN87705.1 - 0.36 11.0 2.3 1.1 9.5 2.3 1.8 1 0 0 1 1 1 0 Zinc knuckle Pyr_redox_2 PF07992.14 KZN87707.1 - 9.4e-46 156.4 0.0 1.3e-45 155.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KZN87707.1 - 6.7e-14 52.2 0.0 1.4e-11 44.8 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.6 KZN87707.1 - 1.2e-05 25.7 0.0 2.6e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KZN87707.1 - 2e-05 23.8 0.1 6e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KZN87707.1 - 0.00017 21.2 0.1 0.00052 19.7 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KZN87707.1 - 0.00059 19.2 0.1 0.0055 16.2 0.0 2.3 2 0 0 2 2 2 1 EF hand VEGFR-2_TMD PF17988.1 KZN87707.1 - 7.8 6.0 6.2 33 4.0 0.0 2.5 2 0 0 2 2 2 0 VEGFR-2 Transmembrane domain CLTH PF10607.9 KZN87708.1 - 1.2e-22 80.4 0.1 1.6e-22 80.0 0.1 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-C2H2 PF00096.26 KZN87709.1 - 0.0002 21.7 9.3 0.051 14.0 0.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KZN87709.1 - 0.00049 20.4 0.2 0.00049 20.4 0.2 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KZN87709.1 - 0.0024 18.6 5.4 2 9.4 0.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf_Hakai PF18408.1 KZN87709.1 - 0.36 10.6 2.8 0.98 9.2 0.4 2.4 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain Ank_2 PF12796.7 KZN87710.1 - 9e-43 144.8 0.0 7.8e-13 48.8 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN87710.1 - 7.8e-42 141.1 0.0 2.6e-08 34.2 0.0 5.3 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN87710.1 - 1.8e-40 132.3 0.0 8.1e-05 22.7 0.0 7.1 7 0 0 7 7 7 7 Ankyrin repeat Ank PF00023.30 KZN87710.1 - 3.8e-38 128.3 0.0 2.6e-06 27.6 0.0 7.1 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.6 KZN87710.1 - 2.6e-24 85.0 0.0 1.4e-06 28.5 0.0 4.8 2 2 4 6 6 6 6 Ankyrin repeats (many copies) VWA_3_C PF18571.1 KZN87710.1 - 0.3 11.0 6.3 30 4.6 0.0 4.6 5 0 0 5 5 5 0 von Willebrand factor type A C-terminal domain Imm_superinfect PF14373.6 KZN87710.1 - 2.3 8.2 5.2 58 3.7 0.1 4.2 5 0 0 5 5 5 0 Superinfection immunity protein FixS PF03597.15 KZN87710.1 - 4.7 7.0 4.6 33 4.3 0.1 3.0 3 0 0 3 3 3 0 Cytochrome oxidase maturation protein cbb3-type APG6_N PF17675.1 KZN87711.1 - 7.1e-05 23.4 2.6 7.1e-05 23.4 2.6 2.0 2 0 0 2 2 2 1 Apg6 coiled-coil region HALZ PF02183.18 KZN87711.1 - 0.0075 16.5 2.9 0.023 14.9 0.7 2.4 2 0 0 2 2 2 1 Homeobox associated leucine zipper CortBP2 PF09727.9 KZN87711.1 - 0.022 14.6 4.3 0.038 13.9 4.3 1.3 1 0 0 1 1 1 0 Cortactin-binding protein-2 ZapB PF06005.12 KZN87711.1 - 0.039 14.4 4.4 0.039 14.4 4.4 2.7 2 2 0 2 2 2 0 Cell division protein ZapB FapA PF03961.13 KZN87711.1 - 0.09 11.4 1.9 0.12 10.9 1.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A WD40_alt PF14077.6 KZN87711.1 - 0.2 11.6 0.7 23 5.0 0.0 2.4 2 0 0 2 2 2 0 Alternative WD40 repeat motif YabA PF06156.13 KZN87711.1 - 0.23 12.1 5.0 0.65 10.7 1.3 2.5 2 2 0 2 2 2 0 Initiation control protein YabA DivIC PF04977.15 KZN87711.1 - 0.41 10.4 4.6 0.52 10.1 3.0 2.1 1 1 0 1 1 1 0 Septum formation initiator GCN5L1 PF06320.13 KZN87711.1 - 0.51 10.5 7.1 2.2 8.5 0.3 2.4 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) TMF_TATA_bd PF12325.8 KZN87711.1 - 0.97 9.7 7.1 1.5 9.1 4.0 2.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding HIP1_clath_bdg PF16515.5 KZN87711.1 - 3.6 8.3 11.0 0.36 11.5 3.6 2.6 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 IFT20 PF14931.6 KZN87711.1 - 4.3 7.5 8.8 24 5.1 4.9 3.0 1 1 2 3 3 3 0 Intraflagellar transport complex B, subunit 20 Thioredoxin_4 PF13462.6 KZN87712.1 - 0.00018 21.7 0.0 0.00034 20.8 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin Phage_TAC_6 PF09550.10 KZN87712.1 - 0.013 15.9 0.1 0.026 14.9 0.1 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC NDUF_C2 PF06374.11 KZN87713.1 - 0.0039 17.3 5.9 4.9 7.3 0.4 3.6 1 1 3 4 4 4 4 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Pro-rich PF15240.6 KZN87713.1 - 0.66 10.2 20.1 1.7 8.9 5.3 2.0 1 1 1 2 2 2 0 Proline-rich MARVEL PF01284.23 KZN87714.1 - 2.8e-07 30.6 3.7 3.8e-07 30.2 3.7 1.2 1 0 0 1 1 1 1 Membrane-associating domain E1-E2_ATPase PF00122.20 KZN87715.1 - 1.6e-36 125.5 10.9 3.9e-35 121.0 2.6 4.0 3 1 0 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.26 KZN87715.1 - 9.5e-18 65.2 0.2 2.6e-17 63.8 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KZN87715.1 - 1.8e-09 37.1 0.0 4e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KZN87715.1 - 0.0033 17.2 1.4 0.04 13.7 0.1 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase TRAP_beta PF05753.14 KZN87715.1 - 0.015 14.7 0.0 0.048 13.0 0.0 1.8 2 0 0 2 2 2 0 Translocon-associated protein beta (TRAPB) Cation_ATPase PF13246.6 KZN87715.1 - 0.024 14.7 0.0 0.057 13.5 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) GSK-3_bind PF05350.12 KZN87715.1 - 0.12 11.7 0.1 0.22 10.8 0.1 1.3 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding GNVR PF13807.6 KZN87715.1 - 0.27 11.2 1.8 0.61 10.0 0.0 2.6 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase Ank_2 PF12796.7 KZN87719.1 - 6.5e-11 42.7 0.0 1.1e-10 42.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN87719.1 - 7.4e-08 32.8 0.0 0.00095 19.7 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN87719.1 - 2.1e-07 30.7 0.0 0.0013 19.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KZN87719.1 - 4e-07 30.2 0.0 0.00064 20.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KZN87719.1 - 1.3e-06 28.6 0.0 9.7e-06 25.8 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Kdo PF06293.14 KZN87720.1 - 8e-06 25.3 0.0 1.7e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KZN87720.1 - 0.00037 19.9 0.0 0.00078 18.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KZN87720.1 - 0.0052 16.7 0.1 0.0052 16.7 0.1 3.6 3 1 1 4 4 4 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN87720.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Casc1_N PF15927.5 KZN87720.1 - 0.87 9.2 17.6 1.5 8.4 17.6 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus SRF-TF PF00319.18 KZN87721.1 - 0.0012 18.3 0.1 0.0017 17.8 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Zn_clus PF00172.18 KZN87724.1 - 5.7e-08 32.8 16.2 8.6e-08 32.2 2.7 3.8 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-XS PF03470.14 KZN87725.1 - 1.5e-05 25.2 0.1 1.2e+02 3.0 0.0 6.1 6 0 0 6 6 6 0 XS zinc finger domain AcetylCoA_hyd_C PF13336.6 KZN87725.1 - 0.093 12.7 0.2 80 3.1 0.0 3.8 1 1 4 5 5 5 0 Acetyl-CoA hydrolase/transferase C-terminal domain Retrotran_gag_2 PF14223.6 KZN87727.1 - 1.6e-09 37.5 0.0 3e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KZN87727.1 - 2.8e-09 36.4 1.6 3.2e-09 36.2 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 KZN87727.1 - 5.8e-07 29.2 0.0 1.1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 KZN87727.1 - 0.0017 18.2 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain Ank_2 PF12796.7 KZN87728.1 - 1.9e-39 134.1 0.2 1.8e-18 66.9 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KZN87728.1 - 2.1e-34 117.1 3.0 5.2e-10 39.4 0.0 4.7 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KZN87728.1 - 7.6e-34 114.7 0.1 8.8e-06 25.9 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 KZN87728.1 - 1.9e-33 110.7 0.1 1.2e-05 25.3 0.0 6.9 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 KZN87728.1 - 3.1e-33 113.7 2.9 4.3e-08 33.5 0.1 5.6 2 1 4 6 6 6 5 Ankyrin repeats (many copies) F-box PF00646.33 KZN87728.1 - 0.00023 21.0 0.5 0.00051 19.9 0.5 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KZN87728.1 - 0.0044 16.9 0.2 0.0098 15.8 0.2 1.6 1 0 0 1 1 1 1 F-box-like Pribosyltran PF00156.27 KZN87729.1 - 1.8e-20 73.1 0.0 2.2e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KZN87729.1 - 0.00014 21.4 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 KZN87729.1 - 0.0081 15.7 0.0 0.0083 15.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase zf-C2H2 PF00096.26 KZN87730.1 - 0.00049 20.4 8.8 0.028 14.9 0.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KZN87730.1 - 0.0005 20.4 0.2 0.0005 20.4 0.2 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KZN87730.1 - 0.0012 19.5 4.9 1.2 10.2 0.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger Ank_2 PF12796.7 KZN87731.1 - 3.8e-62 206.8 9.9 7.3e-16 58.5 0.0 6.9 2 1 7 9 9 9 8 Ankyrin repeats (3 copies) Ank PF00023.30 KZN87731.1 - 3.4e-45 150.6 12.8 1.7e-06 28.2 0.0 13.1 12 1 1 13 13 13 7 Ankyrin repeat Ank_4 PF13637.6 KZN87731.1 - 2.6e-44 149.0 5.4 6.3e-07 29.8 0.0 9.4 2 2 9 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN87731.1 - 9.6e-39 127.0 1.7 0.00049 20.3 0.0 12.9 13 0 0 13 13 13 8 Ankyrin repeat Ank_5 PF13857.6 KZN87731.1 - 6.9e-27 93.2 6.2 6.6e-05 23.1 0.0 8.2 6 3 4 10 10 10 7 Ankyrin repeats (many copies) F-box-like PF12937.7 KZN87731.1 - 2.4e-05 24.1 1.1 3.7e-05 23.5 0.1 1.8 2 0 0 2 2 2 1 F-box-like BAT PF15915.5 KZN87731.1 - 0.085 12.7 0.9 0.72 9.7 0.1 2.7 2 1 1 3 3 3 0 GAF and HTH_10 associated domain zf-H2C2_2 PF13465.6 KZN87732.1 - 0.0011 19.4 0.3 0.0011 19.4 0.3 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KZN87732.1 - 0.0022 18.7 5.2 1.5 9.8 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KZN87732.1 - 0.0039 17.6 10.1 0.13 12.8 1.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf_Hakai PF18408.1 KZN87732.1 - 0.66 9.7 3.4 0.81 9.4 0.5 2.3 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain APH PF01636.23 KZN87733.1 - 1.2e-05 25.4 0.2 2.3e-05 24.4 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN87733.1 - 0.0019 17.8 0.0 0.003 17.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Ank_2 PF12796.7 KZN87738.1 - 4.7e-49 164.9 3.7 3.6e-10 40.3 0.0 5.9 2 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN87738.1 - 3.8e-37 126.2 12.8 9.7e-07 29.2 0.1 7.6 4 3 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN87738.1 - 1.2e-36 120.5 11.9 0.00054 20.2 0.1 11.3 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.6 KZN87738.1 - 1.7e-35 120.6 19.7 4.7e-09 36.3 0.1 10.8 4 4 7 11 11 11 9 Ankyrin repeats (many copies) Ank PF00023.30 KZN87738.1 - 1e-29 101.6 22.0 1.3e-05 25.4 0.1 10.9 12 0 0 12 12 12 8 Ankyrin repeat F-box-like PF12937.7 KZN87738.1 - 0.0012 18.7 0.1 0.0023 17.8 0.1 1.4 1 0 0 1 1 1 1 F-box-like Retrotran_gag_2 PF14223.6 KZN87740.1 - 2.1e-17 63.1 0.3 3.1e-17 62.5 0.3 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.17 KZN87740.1 - 0.00066 19.9 0.0 0.0015 18.8 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein Retrotran_gag_3 PF14244.6 KZN87740.1 - 0.0017 18.1 0.0 0.0054 16.5 0.0 1.9 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Ras PF00071.22 KZN87741.1 - 1.6e-38 131.9 0.0 3.9e-38 130.6 0.0 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KZN87741.1 - 5.2e-12 46.1 0.0 6.5e-11 42.5 0.0 2.3 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KZN87741.1 - 0.00075 19.6 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ank_4 PF13637.6 KZN87743.1 - 3.2e-08 34.0 0.0 2.6e-05 24.7 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KZN87743.1 - 3.9e-08 33.8 0.0 4.7e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KZN87743.1 - 1.4e-06 28.5 0.0 0.0004 20.7 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KZN87743.1 - 2.2e-06 27.8 0.0 4.6e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN87743.1 - 3.7e-06 26.8 0.0 0.0098 16.3 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Dimer_Tnp_hAT PF05699.14 KZN87744.1 - 8.2e-13 48.0 0.0 2.2e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KZN87744.1 - 0.0082 16.5 1.8 0.0098 16.2 0.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4413) SURF2 PF05477.11 KZN87744.1 - 2.9 7.5 6.6 1.4 8.5 4.0 1.8 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) Virul_fac_BrkB PF03631.15 KZN87745.1 - 0.088 12.4 2.0 0.13 11.8 2.0 1.2 1 0 0 1 1 1 0 Virulence factor BrkB RbsD_FucU PF05025.13 KZN87747.1 - 0.11 12.9 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 RbsD / FucU transport protein family Dimer_Tnp_hAT PF05699.14 KZN87748.1 - 3.4e-11 42.8 0.1 1.4e-10 40.8 0.0 2.2 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 KZN87748.1 - 0.0023 17.9 2.7 0.0059 16.6 2.7 1.7 1 0 0 1 1 1 1 BED zinc finger Kdo PF06293.14 KZN87749.1 - 8.5e-06 25.3 0.0 1.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KZN87749.1 - 0.00036 20.0 0.0 0.00078 18.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KZN87749.1 - 0.0052 16.7 0.1 0.0052 16.7 0.1 3.6 3 1 1 4 4 4 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN87749.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase ORC_WH_C PF18137.1 KZN87749.1 - 1.2 9.2 5.5 11 6.0 6.7 2.0 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal Casc1_N PF15927.5 KZN87749.1 - 1.7 8.3 18.9 3.3 7.4 18.9 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Ank_2 PF12796.7 KZN87750.1 - 1.7e-22 79.8 1.0 4.8e-11 43.1 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN87750.1 - 1.3e-14 54.3 0.4 1.4e-07 32.0 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN87750.1 - 1e-12 47.0 0.3 0.0004 20.6 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 KZN87750.1 - 7.3e-11 42.0 0.3 2.1e-05 24.7 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KZN87750.1 - 1.1e-10 41.6 1.6 2.5e-07 30.8 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) DUF3330 PF11809.8 KZN87752.1 - 0.0019 18.2 0.1 0.0061 16.6 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3330) zf-RING_2 PF13639.6 KZN87752.1 - 0.0037 17.6 8.9 0.0073 16.6 8.9 1.5 1 0 0 1 1 1 1 Ring finger domain RINGv PF12906.7 KZN87752.1 - 0.11 12.7 9.6 0.21 11.7 9.6 1.5 1 0 0 1 1 1 0 RING-variant domain Tudor_3 PF18115.1 KZN87752.1 - 0.13 12.1 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain Zn_ribbon_17 PF17120.5 KZN87752.1 - 0.42 10.3 7.9 1 9.0 7.9 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Ank_2 PF12796.7 KZN87753.1 - 7.9e-53 177.0 6.0 2.8e-11 43.8 0.0 6.2 3 2 2 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KZN87753.1 - 1.1e-41 136.0 13.6 0.00016 21.9 0.1 13.2 13 0 0 13 13 13 11 Ankyrin repeat Ank_4 PF13637.6 KZN87753.1 - 7.4e-41 138.0 17.3 2.8e-08 34.1 0.0 9.2 3 3 7 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 KZN87753.1 - 2.2e-39 133.0 18.9 2.4e-07 30.9 0.1 10.6 4 4 7 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 KZN87753.1 - 1.3e-29 101.3 26.4 1.4e-05 25.3 0.0 11.4 12 0 0 12 12 12 7 Ankyrin repeat F-box-like PF12937.7 KZN87753.1 - 7.7e-05 22.5 0.2 0.00014 21.6 0.2 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN87753.1 - 0.00023 20.9 0.2 0.00053 19.8 0.2 1.7 1 0 0 1 1 1 1 F-box domain SlyX PF04102.12 KZN87755.1 - 0.031 14.9 0.5 0.98 10.1 0.0 2.5 2 0 0 2 2 2 0 SlyX Na_H_Exchanger PF00999.21 KZN87756.1 - 1e-39 136.5 25.6 2.3e-39 135.3 25.6 1.5 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family CP2 PF04516.15 KZN87758.1 - 7.9e-16 58.1 0.0 1.2e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor adh_short_C2 PF13561.6 KZN87760.1 - 7.3e-47 159.9 0.5 9.4e-47 159.5 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN87760.1 - 2.4e-41 141.3 0.6 3.3e-41 140.9 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN87760.1 - 6.7e-11 42.4 0.6 9.5e-11 41.9 0.6 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KZN87760.1 - 4.9e-05 22.9 0.2 0.00013 21.6 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HATPase_c PF02518.26 KZN87760.1 - 0.0035 17.8 0.0 0.01 16.3 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GDP_Man_Dehyd PF16363.5 KZN87760.1 - 0.0039 16.6 0.0 0.0057 16.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_2 PF03446.15 KZN87760.1 - 0.02 15.1 0.0 0.82 9.8 0.0 2.5 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Dimer_Tnp_hAT PF05699.14 KZN87761.1 - 1.6e-08 34.2 0.0 6e-08 32.4 0.0 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region NEMO PF11577.8 KZN87763.1 - 0.93 9.6 5.7 2.5 8.2 5.7 1.6 1 1 0 1 1 1 0 NF-kappa-B essential modulator NEMO RINGv PF12906.7 KZN87765.1 - 0.031 14.4 4.2 0.055 13.6 4.2 1.4 1 0 0 1 1 1 0 RING-variant domain zf-RING_2 PF13639.6 KZN87765.1 - 0.12 12.7 3.9 0.22 11.9 3.9 1.4 1 0 0 1 1 1 0 Ring finger domain Zn_ribbon_17 PF17120.5 KZN87765.1 - 0.24 11.0 3.7 0.49 10.0 3.7 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KZN87765.1 - 0.56 10.4 3.0 0.97 9.7 3.0 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain Dimer_Tnp_hAT PF05699.14 KZN87766.1 - 2.5e-11 43.2 0.0 1.1e-10 41.1 0.0 2.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KZN87766.1 - 1.9e-06 28.2 0.2 1.1e-05 25.7 0.1 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4413) YkyA PF10368.9 KZN87766.1 - 1.1 9.0 6.1 0.078 12.7 1.0 1.6 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein zf-RanBP PF00641.18 KZN87769.1 - 0.013 14.8 0.2 0.017 14.4 0.2 1.2 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Ank_2 PF12796.7 KZN87774.1 - 7.7e-51 170.6 0.7 3.2e-13 50.1 0.0 5.5 4 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN87774.1 - 9.4e-45 150.4 11.0 1.3e-08 35.2 0.2 8.6 4 3 5 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN87774.1 - 2.6e-38 125.7 9.5 0.00034 20.8 0.0 12.7 13 0 0 13 13 13 8 Ankyrin repeat Ank_5 PF13857.6 KZN87774.1 - 1.2e-33 114.7 13.9 9.3e-10 38.6 0.0 9.8 4 2 7 11 11 11 7 Ankyrin repeats (many copies) Ank PF00023.30 KZN87774.1 - 6.6e-26 89.6 22.1 2.1e-05 24.7 0.1 10.5 11 1 0 11 11 11 6 Ankyrin repeat F-box PF00646.33 KZN87774.1 - 0.033 14.1 0.1 0.066 13.1 0.1 1.5 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KZN87774.1 - 0.035 14.0 0.1 0.062 13.2 0.1 1.4 1 0 0 1 1 1 0 F-box-like AnkUBD PF18418.1 KZN87774.1 - 0.16 12.2 0.1 1.2 9.3 0.0 2.5 3 0 0 3 3 3 0 Ankyrin ubiquitin-binding domain DUF4569 PF15133.6 KZN87775.1 - 0.04 13.6 0.9 0.052 13.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) DUF2745 PF10922.8 KZN87775.1 - 0.12 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2745) SLATT_5 PF18160.1 KZN87777.1 - 6.2 6.1 7.6 0.14 11.5 0.8 1.7 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 Ank_2 PF12796.7 KZN87778.1 - 6e-25 87.7 0.1 3.1e-12 46.9 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN87778.1 - 5.7e-15 55.5 0.0 6e-08 33.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN87778.1 - 2.3e-13 49.0 0.0 1.3e-05 25.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KZN87778.1 - 3.8e-13 49.4 1.7 7.1e-08 32.6 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KZN87778.1 - 3.3e-11 43.1 0.0 4.8e-06 26.8 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Dimer_Tnp_hAT PF05699.14 KZN87780.1 - 4.2e-11 42.5 0.0 1.2e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 KZN87780.1 - 0.0024 17.9 2.7 0.0058 16.6 2.7 1.7 1 0 0 1 1 1 1 BED zinc finger DUF4692 PF15763.5 KZN87781.1 - 0.041 14.4 1.1 0.05 14.1 1.1 1.1 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) RbsD_FucU PF05025.13 KZN87781.1 - 0.067 13.6 0.0 0.088 13.2 0.0 1.1 1 0 0 1 1 1 0 RbsD / FucU transport protein family Virul_fac_BrkB PF03631.15 KZN87783.1 - 0.049 13.2 0.7 0.074 12.7 0.7 1.2 1 0 0 1 1 1 0 Virulence factor BrkB zf-C2H2 PF00096.26 KZN87785.1 - 2e-07 31.1 12.7 0.00054 20.3 2.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KZN87785.1 - 6.1e-05 23.3 3.3 6.1e-05 23.3 3.3 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KZN87785.1 - 0.01 16.6 10.0 0.26 12.2 1.2 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 KZN87785.1 - 0.31 11.5 9.9 4.7 7.7 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type RasGEF PF00617.19 KZN87787.1 - 3.1e-05 24.3 0.0 0.00015 22.1 0.0 2.1 2 1 0 2 2 2 1 RasGEF domain WIYLD PF10440.9 KZN87792.1 - 0.096 12.5 0.0 1.9 8.3 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain Pkinase PF00069.25 KZN87795.1 - 6.4e-09 35.6 0.0 1.6e-08 34.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN87795.1 - 0.042 13.1 0.0 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase Retrotran_gag_2 PF14223.6 KZN87798.1 - 6.5e-14 51.8 0.0 1.1e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KZN87798.1 - 1.4e-08 34.2 1.3 1.8e-08 33.8 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 KZN87798.1 - 1.3e-06 28.1 0.0 2.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 KZN87798.1 - 0.013 15.3 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 GAG-pre-integrase domain rve_3 PF13683.6 KZN87798.1 - 0.044 13.6 0.0 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain NEMO PF11577.8 KZN87799.1 - 0.8 9.8 5.1 2.3 8.3 5.1 1.7 1 1 0 1 1 1 0 NF-kappa-B essential modulator NEMO FAD_binding_8 PF08022.12 KZN87801.1 - 0.079 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 FAD-binding domain zf-C2H2 PF00096.26 KZN87803.1 - 2.9e-06 27.4 11.9 0.00052 20.3 1.9 2.9 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KZN87803.1 - 1e-05 25.7 3.3 1e-05 25.7 3.3 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KZN87803.1 - 0.054 14.4 10.1 0.2 12.6 0.9 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger RasGEF PF00617.19 KZN87804.1 - 5.8e-05 23.4 0.0 0.00039 20.7 0.0 2.3 2 1 0 2 2 2 1 RasGEF domain DUF3330 PF11809.8 KZN87806.1 - 0.0032 17.5 0.1 0.0073 16.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3330) zf-RING_2 PF13639.6 KZN87806.1 - 0.0085 16.4 8.4 0.015 15.6 8.4 1.5 1 0 0 1 1 1 1 Ring finger domain RINGv PF12906.7 KZN87806.1 - 0.1 12.7 9.0 0.19 11.8 9.0 1.5 1 0 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 KZN87806.1 - 0.39 10.4 7.3 0.85 9.3 7.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type CitX PF03802.14 KZN87809.1 - 0.026 14.3 0.1 0.031 14.0 0.1 1.1 1 0 0 1 1 1 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase DUF1943 PF09172.11 KZN87810.1 - 0.00019 20.8 14.3 0.021 14.1 4.1 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF1943) GerPC PF10737.9 KZN87810.1 - 0.013 15.6 12.4 0.022 14.9 12.4 1.4 1 1 0 1 1 1 0 Spore germination protein GerPC TryThrA_C PF12319.8 KZN87810.1 - 0.037 13.5 11.9 0.67 9.4 3.6 2.0 1 1 1 2 2 2 0 Tryptophan-Threonine-rich plasmodium antigen C terminal IAT_beta PF11924.8 KZN87810.1 - 0.087 12.2 6.2 25 4.2 6.2 2.4 1 1 0 1 1 1 0 Inverse autotransporter, beta-domain MatP PF06303.12 KZN87810.1 - 1.3 9.6 12.0 3.6e+03 -1.4 12.0 3.3 1 1 0 1 1 1 0 MatP N-terminal domain SANT_DAMP1_like PF16282.5 KZN87811.1 - 0.027 14.6 0.4 0.046 13.9 0.4 1.3 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 CobT PF06213.12 KZN87812.1 - 0.37 10.1 6.3 0.4 10.0 6.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sua5_yciO_yrdC PF01300.18 KZN87813.1 - 2.3e-12 46.8 0.0 3.2e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination Kdo PF06293.14 KZN87814.1 - 8e-05 22.1 0.1 0.00012 21.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KZN87814.1 - 0.0024 17.5 0.0 0.0038 16.8 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KZN87814.1 - 0.02 14.8 0.2 0.052 13.4 0.2 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 KZN87814.1 - 0.03 13.7 0.0 0.043 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain WaaY PF06176.11 KZN87814.1 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Kdo PF06293.14 KZN87817.1 - 7.5e-06 25.4 0.0 1.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KZN87817.1 - 0.00058 19.3 0.0 0.0014 18.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KZN87817.1 - 0.0044 17.0 0.1 0.0044 17.0 0.1 3.6 2 2 2 4 4 4 1 Phosphotransferase enzyme family DUF2828 PF11443.8 KZN87817.1 - 0.031 12.4 1.4 0.045 11.8 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Choline_kinase PF01633.20 KZN87817.1 - 0.068 12.7 0.3 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase CDC45 PF02724.14 KZN87817.1 - 0.088 11.1 5.2 0.15 10.3 5.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Ank_4 PF13637.6 KZN87819.1 - 2.9e-58 193.5 11.5 8.7e-10 38.9 0.1 8.3 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 KZN87819.1 - 2.6e-56 188.2 10.9 1.6e-15 57.5 1.2 5.4 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KZN87819.1 - 2.1e-47 158.5 18.1 1.6e-09 37.8 0.6 9.3 2 2 8 10 10 10 10 Ankyrin repeats (many copies) Ank PF00023.30 KZN87819.1 - 2.1e-44 148.1 17.7 0.00022 21.5 0.0 10.6 11 0 0 11 11 11 10 Ankyrin repeat Ank_3 PF13606.6 KZN87819.1 - 1.4e-42 138.7 9.9 0.00027 21.1 0.0 11.0 11 0 0 11 11 11 8 Ankyrin repeat TolA PF06519.11 KZN87819.1 - 0.084 13.1 0.2 3 8.1 0.0 3.2 4 0 0 4 4 4 0 TolA C-terminal APH PF01636.23 KZN87823.1 - 0.00082 19.4 3.2 0.0011 19.0 0.9 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KZN87823.1 - 0.0081 15.5 0.1 0.016 14.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KZN87823.1 - 0.12 11.9 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 KZN87823.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain Fungal_trans PF04082.18 KZN87824.1 - 8.3e-27 93.9 1.1 1.1e-26 93.4 1.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN87824.1 - 1.3e-06 28.4 8.7 2.7e-06 27.4 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0561 PF10573.9 KZN87824.1 - 0.21 11.7 1.4 0.47 10.6 1.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 Cyt-b5 PF00173.28 KZN87825.1 - 1.9e-14 53.6 0.0 2.5e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain p450 PF00067.22 KZN87826.1 - 1.9e-70 237.9 0.0 2.2e-70 237.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_1 PF00175.21 KZN87827.1 - 6.1e-34 116.9 0.0 1.1e-33 116.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KZN87827.1 - 3.5e-27 94.6 0.0 1.5e-26 92.6 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 KZN87827.1 - 5.4e-20 71.3 0.4 1.1e-19 70.3 0.4 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KZN87827.1 - 1.8e-06 28.2 0.0 0.00036 20.7 0.0 2.5 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KZN87827.1 - 0.084 13.1 0.0 0.49 10.6 0.0 2.0 1 1 1 2 2 2 0 Siderophore-interacting FAD-binding domain 3HCDH_N PF02737.18 KZN87828.1 - 9.1e-32 110.4 0.0 1.4e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KZN87828.1 - 1.6e-09 38.2 0.0 4e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KZN87828.1 - 0.00018 21.7 0.0 0.00031 20.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 KZN87828.1 - 0.00025 21.1 0.0 0.00047 20.2 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF5050 PF16472.5 KZN87828.1 - 0.0026 17.1 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF5050) 2-Hacid_dh_C PF02826.19 KZN87828.1 - 0.029 13.8 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KZN87828.1 - 0.064 13.8 0.0 0.18 12.4 0.0 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KZN87829.1 - 8.6e-41 139.8 0.0 1.3e-40 139.2 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KZN87829.1 - 5.5e-10 39.7 0.0 9.1e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.19 KZN87829.1 - 0.00054 19.4 0.0 0.00098 18.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 KZN87829.1 - 0.068 12.7 0.1 0.066 12.8 0.1 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 KZN87829.1 - 0.091 12.3 0.1 0.17 11.5 0.1 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 KZN87829.1 - 0.16 12.1 0.0 0.29 11.3 0.0 1.5 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KZN87829.1 - 0.17 12.5 0.0 0.53 10.9 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ADH_N PF08240.12 KZN87830.1 - 1.6e-17 63.4 0.0 4.1e-17 62.0 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN87830.1 - 1.6e-08 34.6 0.7 7.3e-08 32.5 0.7 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KZN87830.1 - 0.0013 18.3 0.0 0.0038 16.8 0.1 1.7 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus HI0933_like PF03486.14 KZN87830.1 - 0.033 12.9 0.1 0.048 12.4 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.21 KZN87830.1 - 0.034 13.4 0.5 0.055 12.8 0.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KZN87830.1 - 0.17 11.7 0.3 0.25 11.2 0.3 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 KZN87831.1 - 6.7e-31 107.5 34.7 2.5e-30 105.6 30.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short_C2 PF13561.6 KZN87832.1 - 4e-56 190.2 0.0 5.2e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN87832.1 - 9.9e-45 152.4 0.0 1.2e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN87832.1 - 2.6e-12 47.0 0.0 3.7e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KZN87832.1 - 0.038 13.3 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) 6PGD PF00393.19 KZN87833.1 - 2.3e-81 273.3 0.0 2.9e-81 273.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KZN87833.1 - 7.3e-36 123.7 0.0 1.4e-35 122.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 KZN87833.1 - 3.8e-06 27.0 0.0 6.9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 KZN87833.1 - 4.7e-06 26.6 0.1 8.6e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KZN87833.1 - 0.00028 20.5 0.0 0.00065 19.3 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KZN87833.1 - 0.00032 20.1 0.0 0.00059 19.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KZN87833.1 - 0.0032 18.0 0.0 0.01 16.4 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 KZN87833.1 - 0.012 16.2 0.0 0.033 14.8 0.0 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 KZN87833.1 - 0.014 14.7 0.0 0.032 13.5 0.0 1.6 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KZN87833.1 - 0.02 14.1 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KZN87833.1 - 0.035 14.4 0.0 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.6 KZN87833.1 - 0.083 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KZN87833.1 - 0.19 11.8 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PMI_typeI PF01238.21 KZN87834.1 - 5.6e-14 52.1 0.1 2.5e-12 46.7 0.0 2.0 1 1 1 2 2 2 2 Phosphomannose isomerase type I Epimerase PF01370.21 KZN87838.1 - 4.9e-23 81.8 0.0 7.8e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KZN87838.1 - 1.5e-17 64.0 0.2 8.5e-12 45.1 0.0 3.0 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KZN87838.1 - 9.2e-11 41.4 0.4 3e-07 29.9 0.0 3.0 2 1 1 3 3 3 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KZN87838.1 - 4.3e-08 32.6 0.0 6.3e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KZN87838.1 - 1.6e-06 27.5 0.2 8.8e-06 25.1 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein KR PF08659.10 KZN87838.1 - 0.24 11.3 0.6 14 5.5 0.0 2.6 3 0 0 3 3 3 0 KR domain Helo_like_N PF17111.5 KZN87839.1 - 8.5e-60 201.7 2.0 1.6e-59 200.8 2.0 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins DUF16 PF01519.16 KZN87839.1 - 0.01 16.3 1.8 0.67 10.5 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function DUF16 Syntaxin-6_N PF09177.11 KZN87839.1 - 0.016 15.7 3.8 0.69 10.5 0.6 3.7 1 1 1 3 3 3 0 Syntaxin 6, N-terminal SesA PF17107.5 KZN87839.1 - 0.018 15.2 1.2 0.24 11.6 0.1 2.3 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases NPV_P10 PF05531.12 KZN87839.1 - 0.14 12.7 0.8 5.4 7.6 0.1 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1993 PF09351.10 KZN87839.1 - 0.14 12.3 1.6 0.36 11.0 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) FUSC PF04632.12 KZN87839.1 - 2.2 6.7 18.2 0.029 12.9 0.5 2.9 1 1 1 3 3 3 0 Fusaric acid resistance protein family Muted PF14942.6 KZN87839.1 - 4.9 7.5 8.5 2.1 8.7 0.7 2.9 2 1 1 3 3 3 0 Organelle biogenesis, Muted-like protein SANT_DAMP1_like PF16282.5 KZN87841.1 - 0.022 15.0 0.2 0.037 14.2 0.2 1.3 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 bZIP_1 PF00170.21 KZN87843.1 - 8.7e-07 28.9 7.6 1.4e-06 28.3 7.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KZN87843.1 - 1e-06 28.7 7.1 1.9e-06 27.9 7.1 1.4 1 0 0 1 1 1 1 Basic region leucine zipper PEPCK_ATP PF01293.20 KZN87843.1 - 0.14 10.8 0.0 0.18 10.5 0.0 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase MscS_TM PF12794.7 KZN87843.1 - 3.2 6.5 3.6 4.3 6.1 3.6 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF4625 PF15418.6 KZN87845.1 - 0.0033 17.7 0.0 0.0052 17.0 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4625) Glyco_hydro_61 PF03443.14 KZN87845.1 - 0.024 14.6 0.0 0.035 14.0 0.0 1.5 1 1 0 1 1 1 0 Glycosyl hydrolase family 61 MAPKK1_Int PF08923.10 KZN87847.1 - 0.0079 16.0 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting YabA PF06156.13 KZN87848.1 - 0.0017 18.9 0.8 0.0029 18.2 0.8 1.4 1 0 0 1 1 1 1 Initiation control protein YabA DUF1664 PF07889.12 KZN87848.1 - 0.003 17.6 1.8 0.0045 17.0 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) RILP PF11461.8 KZN87848.1 - 0.011 16.0 0.3 0.022 15.0 0.3 1.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein CENP-H PF05837.12 KZN87848.1 - 0.013 15.9 4.4 0.024 15.1 4.4 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) THOC7 PF05615.13 KZN87848.1 - 0.014 15.7 2.4 0.018 15.3 2.4 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 Lipoprotein_2 PF00921.17 KZN87848.1 - 0.021 14.4 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Borrelia lipoprotein Atg14 PF10186.9 KZN87848.1 - 0.022 13.9 2.7 0.026 13.6 2.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ZapB PF06005.12 KZN87848.1 - 0.022 15.2 2.3 0.038 14.4 2.3 1.4 1 0 0 1 1 1 0 Cell division protein ZapB TSC22 PF01166.18 KZN87848.1 - 0.023 15.0 0.7 0.046 14.0 0.7 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family RasGAP_C PF03836.15 KZN87848.1 - 0.039 14.1 0.7 0.058 13.5 0.7 1.3 1 0 0 1 1 1 0 RasGAP C-terminus TMCO5 PF14992.6 KZN87848.1 - 0.05 13.2 1.0 0.066 12.8 1.0 1.2 1 0 0 1 1 1 0 TMCO5 family FlxA PF14282.6 KZN87848.1 - 0.058 13.4 4.7 0.097 12.7 4.7 1.4 1 0 0 1 1 1 0 FlxA-like protein LRRFIP PF09738.9 KZN87848.1 - 0.067 12.7 4.4 0.062 12.8 3.2 1.4 1 1 0 1 1 1 0 LRRFIP family DivIC PF04977.15 KZN87848.1 - 0.28 11.0 5.1 0.64 9.8 5.1 1.6 1 1 0 1 1 1 0 Septum formation initiator NRBF2 PF08961.10 KZN87848.1 - 0.28 10.8 5.5 0.26 10.8 4.3 1.5 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator FUSC PF04632.12 KZN87848.1 - 0.46 9.0 5.7 0.59 8.6 5.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family SlyX PF04102.12 KZN87848.1 - 0.54 10.9 6.3 6.9 7.4 6.3 2.3 1 1 0 1 1 1 0 SlyX DSL PF01414.19 KZN87849.1 - 0.14 12.5 1.2 0.2 11.9 1.2 1.2 1 0 0 1 1 1 0 Delta serrate ligand Glyco_transf_20 PF00982.21 KZN87850.1 - 4.9e-154 513.5 0.0 5.7e-154 513.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 KZN87850.1 - 0.00024 20.7 0.0 0.0033 17.0 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KZN87850.1 - 0.008 16.6 0.1 0.037 14.5 0.1 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Retrotran_gag_2 PF14223.6 KZN87852.1 - 1.8e-12 47.1 0.0 2.9e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KZN87852.1 - 1.1e-09 37.7 0.1 2.3e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 KZN87852.1 - 3.9e-07 29.8 0.0 7.6e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4645 PF15488.6 KZN87855.1 - 0.17 11.3 0.1 0.23 10.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4645) GerPC PF10737.9 KZN87857.1 - 0.0086 16.2 2.7 0.022 14.9 2.5 1.6 1 1 1 2 2 2 2 Spore germination protein GerPC DUF1943 PF09172.11 KZN87857.1 - 0.023 14.0 7.5 0.038 13.2 7.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) TryThrA_C PF12319.8 KZN87857.1 - 0.097 12.1 0.8 0.21 11.1 0.8 1.6 1 0 0 1 1 1 0 Tryptophan-Threonine-rich plasmodium antigen C terminal Zn_clus PF00172.18 KZN87858.1 - 1.2e-07 31.7 10.9 2.5e-07 30.7 10.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PRIMA1 PF16101.5 KZN87858.1 - 3.8 7.6 10.8 0.44 10.6 3.1 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 KZN87858.1 - 6.5 6.8 5.7 2.3 8.2 0.3 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator Pkinase PF00069.25 KZN87860.1 - 3.4e-55 187.2 0.1 4.1e-55 187.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN87860.1 - 2.8e-28 98.9 0.0 3.4e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KZN87860.1 - 9.8e-05 21.8 0.0 0.0002 20.8 0.0 1.5 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KZN87860.1 - 0.098 11.6 0.3 0.12 11.2 0.3 1.3 1 1 0 1 1 1 0 Haspin like kinase domain DUF4413 PF14372.6 KZN87861.1 - 0.00053 20.3 0.0 0.00099 19.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) Dimer_Tnp_hAT PF05699.14 KZN87861.1 - 0.00088 19.0 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region MFS_1 PF07690.16 KZN87864.1 - 1.8e-25 89.7 6.5 2.2e-25 89.3 6.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN87864.1 - 7.2e-12 44.9 7.9 1.6e-11 43.8 8.0 1.5 1 1 1 2 2 2 1 Sugar (and other) transporter BT1 PF03092.16 KZN87864.1 - 0.046 12.0 4.2 0.013 13.8 1.2 1.4 1 1 0 1 1 1 0 BT1 family DUF2841 PF11001.8 KZN87866.1 - 2e-47 160.3 0.4 2.9e-47 159.8 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) MgtE PF01769.16 KZN87867.1 - 0.018 15.4 0.6 0.018 15.4 0.6 3.1 1 1 2 3 3 3 0 Divalent cation transporter DUF5096 PF17019.5 KZN87867.1 - 0.095 12.5 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5096) RhoGEF PF00621.20 KZN87869.1 - 3.9e-31 108.7 0.2 2.7e-30 106.0 0.0 2.3 3 0 0 3 3 3 1 RhoGEF domain ACP_PD PF04336.12 KZN87869.1 - 0.22 12.0 3.3 36 4.8 0.1 3.6 1 1 2 3 3 3 0 Acyl carrier protein phosphodiesterase ATP-synt_D PF01813.17 KZN87869.1 - 0.25 11.1 3.3 0.23 11.2 1.0 2.1 2 0 0 2 2 2 0 ATP synthase subunit D Cyclin_N PF00134.23 KZN87870.1 - 2.3e-10 40.3 0.5 4.3e-10 39.4 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.11 KZN87870.1 - 5.9e-09 36.5 0.0 9.9e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin IFP_35_N PF07334.13 KZN87870.1 - 1 9.5 5.7 2.4 8.3 5.7 1.6 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Catalase PF00199.19 KZN87871.1 - 1.7e-61 208.5 4.2 6.1e-34 117.8 0.1 3.1 1 1 2 3 3 3 3 Catalase Catalase-rel PF06628.12 KZN87871.1 - 4e-11 43.0 0.2 7e-11 42.2 0.2 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive PP2C PF00481.21 KZN87872.1 - 1.2e-27 97.1 0.6 1.6e-27 96.8 0.6 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KZN87872.1 - 5.8e-05 23.1 0.2 0.014 15.3 0.1 2.1 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KZN87872.1 - 0.00013 21.6 0.3 0.18 11.5 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C Caleosin PF05042.13 KZN87874.1 - 8.2e-75 250.4 0.4 1e-74 250.1 0.4 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_1 PF00036.32 KZN87874.1 - 2.6e-05 23.5 5.3 0.00014 21.1 0.1 3.4 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.6 KZN87874.1 - 0.00011 21.8 8.1 0.00023 20.8 0.3 3.5 4 0 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.6 KZN87874.1 - 0.0033 17.3 0.1 0.077 12.9 0.1 2.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.6 KZN87874.1 - 0.0052 17.2 1.1 0.055 13.9 0.6 2.6 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KZN87874.1 - 0.014 14.8 0.4 0.014 14.8 0.4 3.6 4 0 0 4 4 4 0 EF hand Hyr1 PF15789.5 KZN87875.1 - 0.7 9.5 2.8 2.2 7.9 0.5 2.5 2 0 0 2 2 2 0 Hyphally regulated cell wall GPI-anchored protein 1 DUF1959 PF09218.10 KZN87878.1 - 0.12 12.5 0.5 0.22 11.6 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1959) Pkinase_Tyr PF07714.17 KZN87879.1 - 0.01 15.2 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3330 PF11809.8 KZN87880.1 - 0.0028 17.7 0.1 0.0069 16.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3330) zf-RING_2 PF13639.6 KZN87880.1 - 0.0063 16.8 9.5 0.011 16.1 9.5 1.4 1 0 0 1 1 1 1 Ring finger domain RINGv PF12906.7 KZN87880.1 - 0.1 12.7 10.0 0.19 11.9 10.0 1.5 1 0 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 KZN87880.1 - 0.62 9.7 7.5 1.3 8.7 7.5 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KZN87880.1 - 1.6 9.0 6.2 2.9 8.1 6.2 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-rbx1 PF12678.7 KZN87880.1 - 2.8 8.3 7.4 7.1 7.0 7.3 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain Ank_2 PF12796.7 KZN87881.1 - 6.2e-48 161.3 5.2 6.6e-11 42.7 0.0 6.1 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KZN87881.1 - 9.1e-39 127.0 12.4 0.00029 21.1 0.0 11.2 11 0 0 11 11 11 10 Ankyrin repeat Ank_5 PF13857.6 KZN87881.1 - 5.5e-38 128.5 15.2 1.3e-08 35.0 0.0 9.1 3 3 6 9 9 9 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 KZN87881.1 - 3.9e-35 119.8 14.3 1.7e-06 28.4 0.1 7.8 3 3 6 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 KZN87881.1 - 3.6e-30 103.1 19.7 1e-05 25.8 0.0 10.0 11 0 0 11 11 11 8 Ankyrin repeat DAP_epimerase PF01678.19 KZN87884.1 - 0.022 14.9 0.0 0.032 14.4 0.0 1.2 1 0 0 1 1 1 0 Diaminopimelate epimerase Peptidase_C27 PF05407.12 KZN87885.1 - 0.0016 18.6 0.6 1.5 8.9 0.0 3.9 1 1 2 4 4 4 2 Rubella virus endopeptidase CLASP_N PF12348.8 KZN87885.1 - 3.5 7.1 13.9 63 3.0 0.1 6.8 1 1 6 8 8 8 0 CLASP N terminal Methyltrans_Mon PF14314.6 KZN87886.1 - 0.037 12.1 0.5 0.046 11.8 0.5 1.0 1 0 0 1 1 1 0 Virus-capping methyltransferase Get5_C PF18514.1 KZN87887.1 - 0.093 12.5 0.1 0.35 10.6 0.0 2.0 2 0 0 2 2 2 0 Get5 C-terminal domain CENP-F_leu_zip PF10473.9 KZN87888.1 - 0.00053 20.0 1.4 0.00096 19.2 1.4 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KZN87888.1 - 0.00054 19.0 2.7 0.00076 18.5 2.7 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Seryl_tRNA_N PF02403.22 KZN87888.1 - 0.0022 18.2 2.1 0.004 17.4 2.1 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain IFT57 PF10498.9 KZN87888.1 - 0.0025 16.8 0.2 0.0031 16.5 0.2 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 HAP1_N PF04849.13 KZN87888.1 - 0.0026 17.0 0.3 0.0035 16.6 0.3 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region YabA PF06156.13 KZN87888.1 - 0.0034 18.0 0.5 0.0063 17.1 0.5 1.4 1 0 0 1 1 1 1 Initiation control protein YabA ADIP PF11559.8 KZN87888.1 - 0.0034 17.5 1.7 0.0062 16.6 1.7 1.4 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Prominin PF05478.11 KZN87888.1 - 0.0065 14.5 0.9 0.0079 14.2 0.9 1.0 1 0 0 1 1 1 1 Prominin CEP63 PF17045.5 KZN87888.1 - 0.0078 16.1 0.7 0.011 15.6 0.7 1.2 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa TPR_MLP1_2 PF07926.12 KZN87888.1 - 0.011 15.8 2.9 0.064 13.3 0.2 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 KZN87888.1 - 0.012 15.9 0.7 0.023 14.9 0.7 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding GAS PF13851.6 KZN87888.1 - 0.014 14.7 0.5 0.029 13.7 0.5 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 KZN87888.1 - 0.018 14.1 1.3 0.024 13.8 1.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 K-box PF01486.17 KZN87888.1 - 0.019 15.1 2.2 0.037 14.2 2.2 1.5 1 0 0 1 1 1 0 K-box region Filament PF00038.21 KZN87888.1 - 0.019 14.6 0.8 0.03 13.9 0.8 1.3 1 0 0 1 1 1 0 Intermediate filament protein HIP1_clath_bdg PF16515.5 KZN87888.1 - 0.019 15.5 0.1 0.041 14.5 0.1 1.5 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4201 PF13870.6 KZN87888.1 - 0.02 14.6 1.7 0.032 13.9 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Fez1 PF06818.15 KZN87888.1 - 0.023 15.2 0.4 0.034 14.6 0.4 1.3 1 0 0 1 1 1 0 Fez1 TMPIT PF07851.13 KZN87888.1 - 0.026 13.8 0.6 0.035 13.4 0.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein EzrA PF06160.12 KZN87888.1 - 0.026 12.7 0.9 0.033 12.4 0.9 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA HALZ PF02183.18 KZN87888.1 - 0.029 14.6 1.8 0.17 12.1 0.2 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper SOGA PF11365.8 KZN87888.1 - 0.031 15.4 1.7 0.5 11.5 0.2 2.3 1 1 1 2 2 2 0 Protein SOGA Rogdi_lz PF10259.9 KZN87888.1 - 0.035 13.6 0.3 0.043 13.3 0.3 1.2 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein DUF1640 PF07798.11 KZN87888.1 - 0.038 14.0 3.4 0.3 11.1 3.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) HAUS6_N PF14661.6 KZN87888.1 - 0.039 13.5 0.1 0.039 13.5 0.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus PEP-utilisers_N PF05524.13 KZN87888.1 - 0.043 14.0 0.3 0.067 13.4 0.3 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal TolA_bind_tri PF16331.5 KZN87888.1 - 0.046 13.8 0.4 4 7.6 0.0 2.3 1 1 1 2 2 2 0 TolA binding protein trimerisation APG6_N PF17675.1 KZN87888.1 - 0.052 14.1 0.4 0.052 14.1 0.4 1.4 2 0 0 2 2 1 0 Apg6 coiled-coil region RPW8 PF05659.11 KZN87888.1 - 0.058 13.1 0.3 0.085 12.6 0.3 1.3 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 THOC7 PF05615.13 KZN87888.1 - 0.099 12.9 3.4 0.27 11.5 3.1 1.7 1 1 0 1 1 1 0 Tho complex subunit 7 Uso1_p115_C PF04871.13 KZN87888.1 - 0.099 13.0 1.6 0.15 12.4 1.6 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2968 PF11180.8 KZN87888.1 - 0.13 11.9 0.8 0.19 11.3 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) FlaC_arch PF05377.11 KZN87888.1 - 0.14 12.5 0.9 11 6.5 0.1 2.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) YscO PF07321.12 KZN87888.1 - 0.28 11.1 7.7 0.96 9.4 0.3 2.6 2 1 1 3 3 3 0 Type III secretion protein YscO ZapB PF06005.12 KZN87888.1 - 1.5 9.4 7.0 0.36 11.3 1.3 2.5 2 1 1 3 3 3 0 Cell division protein ZapB LAB_N PF07578.11 KZN87890.1 - 0.061 13.4 0.2 0.24 11.5 0.1 2.0 2 0 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain DUF3723 PF12520.8 KZN87891.1 - 1.7e-68 231.5 0.1 1e-61 209.2 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF3723) BAR_2 PF10455.9 KZN87895.1 - 0.035 13.3 0.1 0.048 12.8 0.1 1.2 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Dimer_Tnp_hAT PF05699.14 KZN87897.1 - 5e-13 48.6 0.1 1.7e-12 46.9 0.0 1.9 3 0 0 3 3 3 1 hAT family C-terminal dimerisation region Patatin PF01734.22 KZN87898.1 - 1.1e-21 77.9 0.4 2.8e-21 76.6 0.4 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase zf-C3HC4_3 PF13920.6 KZN87898.1 - 2.8e-05 23.9 5.9 7.7e-05 22.5 5.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KZN87898.1 - 0.0017 18.2 6.1 0.0067 16.3 6.1 2.0 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KZN87898.1 - 0.0019 18.0 5.2 0.0071 16.2 5.3 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KZN87898.1 - 0.0039 17.1 6.8 0.011 15.7 6.8 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KZN87898.1 - 0.14 12.5 8.5 0.53 10.6 8.5 2.1 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 KZN87898.1 - 2.5 8.0 9.0 1.5 8.7 4.6 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KZN87898.1 - 4 7.6 10.7 1.7 8.7 4.6 3.0 2 0 0 2 2 2 0 RING-type zinc-finger BaxI_1 PF12811.7 KZN87899.1 - 0.019 14.6 0.2 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 Bax inhibitor 1 like Phage_holin_3_3 PF16083.5 KZN87899.1 - 1.1 9.4 6.6 0.6 10.3 3.4 2.1 2 1 1 3 3 3 0 LydA holin phage, holin superfamily III Glyco_hydro_61 PF03443.14 KZN87901.1 - 0.0056 16.6 0.0 0.0087 16.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4625 PF15418.6 KZN87901.1 - 0.012 15.9 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) MAP7 PF05672.11 KZN87903.1 - 0.055 13.2 11.3 0.084 12.6 11.3 1.3 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DUF4407 PF14362.6 KZN87903.1 - 0.21 10.9 5.0 0.27 10.6 5.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FUSC PF04632.12 KZN87903.1 - 0.81 8.2 2.8 0.99 7.9 2.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 KZN87903.1 - 2.1 8.4 7.2 3.6 7.6 7.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Aa_trans PF01490.18 KZN87904.1 - 1e-74 251.7 27.4 1.2e-74 251.5 27.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Dimer_Tnp_hAT PF05699.14 KZN87905.1 - 2.5e-13 49.6 0.0 1.4e-12 47.2 0.0 2.4 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KZN87905.1 - 1.4e-06 28.6 0.3 8.9e-06 26.0 0.1 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4413) YkyA PF10368.9 KZN87905.1 - 0.073 12.7 3.0 0.04 13.6 0.8 1.6 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF3330 PF11809.8 KZN87906.1 - 0.0033 17.5 0.1 0.0076 16.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3330) zf-RING_2 PF13639.6 KZN87906.1 - 0.0063 16.8 7.7 0.012 15.9 7.7 1.5 1 0 0 1 1 1 1 Ring finger domain RINGv PF12906.7 KZN87906.1 - 0.095 12.8 8.3 0.19 11.9 8.3 1.5 1 0 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 KZN87906.1 - 0.66 9.6 7.7 1.5 8.5 7.7 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Pkinase_Tyr PF07714.17 KZN87907.1 - 0.011 15.0 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 KZN87907.1 - 0.086 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain DUF3435 PF11917.8 KZN87909.1 - 2.6e-161 537.2 0.6 4.9e-161 536.3 0.2 1.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3435) zf-C2H2_4 PF13894.6 KZN87909.1 - 0.0059 17.3 3.9 0.022 15.6 0.4 3.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KZN87909.1 - 0.5 10.9 2.8 0.94 10.1 0.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF4407 PF14362.6 KZN87909.1 - 6.1 6.1 6.3 11 5.2 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) XFP_N PF09364.10 KZN87911.1 - 2.3e-173 576.1 0.0 3e-173 575.7 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 KZN87911.1 - 7.3e-84 280.2 0.0 1.2e-83 279.5 0.0 1.4 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 KZN87911.1 - 6.5e-82 273.5 0.0 1e-81 272.8 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Methyltransf_25 PF13649.6 KZN87912.1 - 4.5e-19 69.0 0.0 1e-18 67.8 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN87912.1 - 2.3e-17 63.4 0.0 5.4e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN87912.1 - 7.5e-15 55.1 0.0 1e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN87912.1 - 7.7e-13 49.0 0.0 1.6e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN87912.1 - 2.9e-11 43.4 0.0 3.7e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KZN87912.1 - 2.6e-08 33.5 0.0 3.5e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KZN87912.1 - 1.3e-05 24.9 0.0 2.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.18 KZN87912.1 - 1.4e-05 24.7 0.1 0.14 11.6 0.0 2.6 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain CMAS PF02353.20 KZN87912.1 - 0.00019 20.8 0.0 0.00033 20.0 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 KZN87912.1 - 0.00046 19.6 0.0 0.00052 19.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain NodS PF05401.11 KZN87912.1 - 0.00094 18.9 0.0 0.0012 18.5 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_16 PF10294.9 KZN87912.1 - 0.0084 15.9 0.0 0.02 14.7 0.0 1.5 1 1 0 1 1 1 1 Lysine methyltransferase N2227 PF07942.12 KZN87912.1 - 0.015 14.5 0.0 0.26 10.5 0.0 2.2 1 1 1 2 2 2 0 N2227-like protein Nse4_C PF08743.10 KZN87913.1 - 5.9e-34 116.2 0.0 1.7e-33 114.7 0.0 1.9 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KZN87913.1 - 2.5e-16 59.5 0.7 1.1e-15 57.5 0.7 2.1 1 1 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE PI3Ka PF00613.20 KZN87914.1 - 2e-57 193.6 0.4 3.3e-57 192.9 0.4 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KZN87914.1 - 1.3e-43 149.6 0.0 1.1e-30 107.3 0.0 2.6 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KZN87914.1 - 1.6e-28 99.4 0.0 2.6e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Gpr1_Fun34_YaaH PF01184.19 KZN87915.1 - 1.8e-71 240.0 16.9 2.2e-71 239.7 16.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Glyco_hydro_32N PF00251.20 KZN87917.1 - 1.9e-53 182.0 0.1 4.1e-35 121.8 0.3 3.1 1 1 2 3 3 3 3 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KZN87917.1 - 4.2e-33 114.6 0.6 7.3e-33 113.8 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal NACHT_sigma PF17106.5 KZN87917.1 - 0.12 12.6 2.5 0.33 11.1 0.6 2.6 2 0 0 2 2 2 0 Sigma domain on NACHT-NTPases Zn_clus PF00172.18 KZN87918.1 - 2.1e-09 37.3 10.7 5.4e-09 36.0 10.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KZN87918.1 - 0.01 14.7 0.2 0.021 13.7 0.2 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain RTA1 PF04479.13 KZN87919.1 - 7.9e-73 244.5 12.0 7.9e-73 244.5 12.0 1.5 2 0 0 2 2 2 1 RTA1 like protein DUF202 PF02656.15 KZN87919.1 - 6.5 7.3 11.8 2.5 8.6 0.4 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF202) MMR_HSR1 PF01926.23 KZN87922.1 - 1.3e-14 54.2 0.0 3e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KZN87922.1 - 4.8e-08 33.1 0.2 1.1e-07 31.9 0.2 1.5 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KZN87922.1 - 2.8e-06 26.9 0.1 4.3e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 KZN87922.1 - 5.6e-05 22.6 0.0 8.9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Septin PF00735.18 KZN87922.1 - 0.00084 18.7 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Septin AAA_18 PF13238.6 KZN87922.1 - 0.014 15.9 0.1 0.03 14.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KZN87922.1 - 0.016 15.6 0.0 0.028 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.27 KZN87922.1 - 0.017 14.7 0.0 0.053 13.1 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KZN87922.1 - 0.032 13.7 0.0 0.065 12.7 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Arf PF00025.21 KZN87922.1 - 0.039 13.4 0.0 0.49 9.8 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family TniB PF05621.11 KZN87922.1 - 0.048 13.1 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Dynamin_N PF00350.23 KZN87922.1 - 0.052 13.6 0.2 0.65 10.0 0.0 2.2 1 1 0 2 2 2 0 Dynamin family Roc PF08477.13 KZN87922.1 - 0.063 13.5 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Isy1 PF06246.12 KZN87923.1 - 9.3e-85 284.2 0.9 1.1e-84 284.1 0.9 1.0 1 0 0 1 1 1 1 Isy1-like splicing family DUF1566 PF07603.11 KZN87923.1 - 0.089 13.2 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1566) Myosin_head PF00063.21 KZN87924.1 - 4.2e-264 877.9 0.0 9.6e-264 876.7 0.0 1.7 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 KZN87924.1 - 1.5e-18 66.1 274.7 7.1e-11 40.7 192.0 5.6 1 1 1 2 2 2 2 Myosin tail Myosin_N PF02736.19 KZN87924.1 - 3.7e-09 36.3 0.0 7.6e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain DUF4525 PF15027.6 KZN87924.1 - 0.12 12.1 2.1 0.18 11.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) AAA_22 PF13401.6 KZN87924.1 - 0.15 12.3 0.0 0.15 12.3 0.0 4.7 4 0 0 4 4 4 0 AAA domain zf-C3H1 PF10650.9 KZN87925.1 - 1.6e-13 50.0 0.5 2.6e-13 49.4 0.5 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain DHHC PF01529.20 KZN87926.1 - 7.2e-26 90.9 8.1 7.2e-26 90.9 8.1 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase TMEM208_SND2 PF05620.11 KZN87926.1 - 0.95 9.2 0.0 0.95 9.2 0.0 2.1 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 Glyco_hydro_17 PF00332.18 KZN87929.1 - 6.1e-09 35.9 6.0 1e-05 25.3 0.9 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Rick_17kDa_Anti PF05433.15 KZN87929.1 - 0.0008 19.2 12.4 0.016 15.0 2.4 2.8 2 0 0 2 2 2 2 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 KZN87929.1 - 0.015 15.2 2.4 0.015 15.2 2.4 2.9 3 0 0 3 3 3 0 Glycine zipper ISPD_C PF18706.1 KZN87929.1 - 0.21 11.3 0.1 0.3 10.7 0.1 1.2 1 0 0 1 1 1 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain DUF456 PF04306.13 KZN87929.1 - 1.4 9.2 6.6 0.098 12.9 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF456) DUF1269 PF06897.12 KZN87929.1 - 2 8.8 4.7 1 9.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) SRR1 PF07985.12 KZN87930.1 - 1.8e-18 66.3 0.1 5e-18 64.9 0.1 1.8 2 0 0 2 2 2 1 SRR1 RRP7 PF12923.7 KZN87930.1 - 0.0018 18.4 0.3 0.0042 17.2 0.1 1.7 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Ins134_P3_kin PF05770.11 KZN87932.1 - 0.17 11.4 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Abhydrolase_1 PF00561.20 KZN87934.1 - 6.1e-16 58.8 0.3 7.9e-16 58.5 0.3 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KZN87934.1 - 1.6e-11 43.9 0.0 2.6e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KZN87934.1 - 7.4e-11 43.1 14.6 1e-09 39.3 14.6 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KZN87934.1 - 0.0014 18.4 0.2 0.0054 16.4 0.2 1.8 1 1 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 KZN87934.1 - 0.018 13.9 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Esterase_phd PF10503.9 KZN87934.1 - 0.15 11.5 2.4 0.3 10.5 2.0 1.8 1 1 0 1 1 1 0 Esterase PHB depolymerase Peptidase_M28 PF04389.17 KZN87935.1 - 9.6e-40 136.4 0.2 1.6e-39 135.7 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KZN87935.1 - 3.4e-10 39.8 1.8 1.1e-09 38.2 1.8 1.9 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KZN87935.1 - 0.00032 20.5 0.0 0.00071 19.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KZN87935.1 - 0.018 14.1 0.0 0.11 11.5 0.0 2.2 3 0 0 3 3 3 0 M42 glutamyl aminopeptidase MFS_1 PF07690.16 KZN87936.1 - 2.4e-11 43.2 7.9 2.4e-11 43.2 7.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF21 PF01595.20 KZN87936.1 - 0.037 13.8 0.4 0.072 12.8 0.0 1.8 2 1 0 2 2 2 0 Cyclin M transmembrane N-terminal domain Peptidase_M20 PF01546.28 KZN87937.1 - 1.6e-09 37.7 0.0 2.6e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KZN87937.1 - 6.4e-06 26.1 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Amidase PF01425.21 KZN87938.1 - 8.6e-93 311.7 0.1 7e-92 308.7 0.1 1.9 1 1 0 1 1 1 1 Amidase Fungal_trans_2 PF11951.8 KZN87939.1 - 2.4e-18 66.1 1.0 7.7e-18 64.5 1.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN87939.1 - 1.7e-08 34.5 9.2 3.2e-08 33.5 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KZN87940.1 - 6.1e-24 84.8 0.0 3.1e-23 82.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN87940.1 - 0.00029 20.2 0.0 0.0015 17.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Transferase PF02458.15 KZN87941.1 - 4e-08 32.3 0.0 6.1e-06 25.2 0.0 2.4 2 1 0 2 2 2 2 Transferase family HsbA PF12296.8 KZN87942.1 - 1.9e-10 41.2 0.0 4.7e-10 39.9 0.0 1.6 2 0 0 2 2 2 1 Hydrophobic surface binding protein A PS-DH PF14765.6 KZN87943.1 - 1.4e-65 221.5 0.0 2.6e-65 220.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 KZN87943.1 - 1.7e-65 221.1 0.0 4.2e-65 219.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KZN87943.1 - 1.5e-64 218.5 0.0 2.3e-64 217.9 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 KZN87943.1 - 4.5e-53 180.0 0.0 7.3e-53 179.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein KR PF08659.10 KZN87943.1 - 2.8e-36 125.1 0.0 7.8e-35 120.4 0.0 2.6 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 KZN87943.1 - 4.9e-31 107.2 0.4 1.1e-30 106.1 0.4 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KZN87943.1 - 8.6e-28 97.0 0.0 1.6e-27 96.1 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 KZN87943.1 - 1.5e-21 77.0 0.0 6.6e-21 74.9 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KZN87943.1 - 4.6e-16 60.1 0.0 4.3e-15 56.9 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KZN87943.1 - 1.2e-13 51.2 0.0 4.1e-13 49.4 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 KZN87943.1 - 3.8e-12 46.3 0.0 9.4e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN87943.1 - 1.9e-11 44.5 0.0 8.4e-11 42.4 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN87943.1 - 9.4e-11 41.8 0.0 2.9e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KZN87943.1 - 1.3e-09 37.9 0.0 3.1e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.12 KZN87943.1 - 1.6e-09 38.3 0.0 7.5e-09 36.1 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.19 KZN87943.1 - 1.4e-06 27.6 0.0 1.3e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family ADH_N PF08240.12 KZN87943.1 - 1.9e-05 24.5 0.3 6.7e-05 22.7 0.3 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 KZN87943.1 - 0.0024 17.3 0.3 0.0068 15.8 0.3 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF938 PF06080.12 KZN87943.1 - 0.0049 16.7 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Ubie_methyltran PF01209.18 KZN87943.1 - 0.0088 15.4 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ACP_syn_III PF08545.10 KZN87943.1 - 0.0095 15.8 0.3 0.037 13.9 0.3 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_16 PF10294.9 KZN87943.1 - 0.042 13.6 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase PCMT PF01135.19 KZN87943.1 - 0.072 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PP-binding PF00550.25 KZN87943.1 - 0.086 13.2 0.0 0.31 11.4 0.0 1.9 1 0 0 1 1 1 0 Phosphopantetheine attachment site Methyltransf_28 PF02636.17 KZN87943.1 - 0.16 11.6 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase eIF-5a PF01287.20 KZN87944.1 - 0.00091 19.3 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold MAPEG PF01124.18 KZN87945.1 - 4.9e-08 32.9 2.1 7.2e-08 32.4 2.1 1.2 1 0 0 1 1 1 1 MAPEG family PHD PF00628.29 KZN87946.1 - 4.9e-09 35.9 1.8 1.1e-08 34.8 1.8 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KZN87946.1 - 0.019 14.5 1.8 0.03 13.9 1.8 1.3 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 KZN87946.1 - 2.3 8.1 4.5 2.1 8.3 0.4 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Lectin_legB PF00139.19 KZN87947.1 - 0.036 13.6 0.1 0.056 13.0 0.1 1.2 1 0 0 1 1 1 0 Legume lectin domain MARVEL PF01284.23 KZN87948.1 - 8.2e-09 35.6 1.6 8.2e-09 35.6 1.6 2.0 2 0 0 2 2 2 1 Membrane-associating domain VIT1 PF01988.19 KZN87948.1 - 0.0056 16.6 0.1 0.0057 16.6 0.1 1.2 1 0 0 1 1 1 1 VIT family DUF1752 PF08550.10 KZN87949.1 - 0.002 17.9 0.3 0.0041 16.9 0.3 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DIOX_N PF14226.6 KZN87950.1 - 1.2e-08 35.7 0.0 1.9e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KZN87950.1 - 0.056 13.9 0.0 0.077 13.5 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily adh_short_C2 PF13561.6 KZN87951.1 - 5.9e-54 183.1 0.1 8e-54 182.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN87951.1 - 2.3e-37 128.4 0.2 3.2e-37 127.9 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN87951.1 - 7.7e-12 45.5 0.1 1.1e-11 44.9 0.1 1.1 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KZN87951.1 - 0.0045 16.4 0.0 2 7.7 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase CPSase_L_D2 PF02786.17 KZN87952.1 - 1.8e-73 246.5 0.0 3.6e-73 245.6 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KZN87952.1 - 1.3e-37 128.2 0.0 3.3e-37 126.9 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KZN87952.1 - 1e-35 122.6 0.0 2.1e-35 121.6 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KZN87952.1 - 1.5e-17 63.2 0.3 5.2e-17 61.4 0.3 2.1 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KZN87952.1 - 3.2e-09 36.6 0.0 7.6e-09 35.4 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 KZN87952.1 - 1e-05 25.2 0.1 0.028 14.2 0.1 3.0 2 1 1 3 3 3 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 KZN87952.1 - 6.2e-05 23.1 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KZN87952.1 - 0.0027 17.5 0.0 0.0054 16.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD_3 PF13437.6 KZN87952.1 - 0.0079 16.9 0.1 3.1 8.5 0.0 2.8 2 0 0 2 2 2 1 HlyD family secretion protein ATPgrasp_ST PF14397.6 KZN87952.1 - 0.014 14.6 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp GCV_H PF01597.19 KZN87952.1 - 0.059 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Glycine cleavage H-protein ATXN-1_C PF12547.8 KZN87953.1 - 0.047 14.0 0.5 6.5 7.2 0.2 2.7 2 1 1 3 3 3 0 Capicua transcriptional repressor modulator Peroxidase_ext PF11895.8 KZN87953.1 - 0.18 11.8 0.2 10 6.1 0.0 2.5 1 1 1 2 2 2 0 Fungal peroxidase extension region Acyl-CoA_dh_1 PF00441.24 KZN87955.1 - 4e-40 137.5 1.3 6.2e-40 136.8 1.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KZN87955.1 - 3.2e-33 114.7 0.1 6.4e-33 113.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KZN87955.1 - 1.5e-27 95.6 0.1 3.3e-27 94.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KZN87955.1 - 3.1e-15 56.6 0.2 4.9e-15 56.0 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KZN87955.1 - 0.00043 20.0 0.0 0.0012 18.6 0.0 1.7 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Carboxyl_trans PF01039.22 KZN87956.1 - 7.7e-137 456.9 0.1 9.3e-137 456.6 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Kdo PF06293.14 KZN87957.1 - 0.00019 20.9 0.1 0.00028 20.3 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KZN87957.1 - 0.0026 17.7 0.4 0.0073 16.2 0.4 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KZN87957.1 - 0.0031 17.2 0.0 0.0052 16.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 KZN87957.1 - 0.036 13.4 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain ATG101 PF07855.12 KZN87958.1 - 6.9e-53 178.8 0.0 7.9e-53 178.6 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 Peroxin-3 PF04882.12 KZN87959.1 - 4.9e-173 576.4 0.1 7.7e-173 575.8 0.1 1.3 1 0 0 1 1 1 1 Peroxin-3 CAF1A PF12253.8 KZN87961.1 - 1.8e-20 72.8 7.6 1.8e-20 72.8 7.6 4.2 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A Mem_trans PF03547.18 KZN87961.1 - 2.8 6.2 3.2 4.2 5.7 3.2 1.2 1 0 0 1 1 1 0 Membrane transport protein Raftlin PF15250.6 KZN87961.1 - 6 5.5 20.8 9.7 4.8 20.8 1.4 1 0 0 1 1 1 0 Raftlin IPP-2 PF04979.14 KZN87963.1 - 1.3e-19 71.3 17.4 1.3e-19 71.3 17.4 2.7 2 1 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) DUF3410 PF11890.8 KZN87963.1 - 0.024 14.4 0.5 5.4 6.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3410) MFS_1 PF07690.16 KZN87964.1 - 1e-32 113.4 28.9 6.1e-28 97.8 25.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KZN87964.1 - 0.00097 18.1 1.2 0.00097 18.1 1.2 3.2 2 2 1 3 3 3 2 MFS_1 like family MFS_3 PF05977.13 KZN87964.1 - 0.00099 17.6 4.9 0.00099 17.6 4.9 2.6 3 0 0 3 3 3 1 Transmembrane secretion effector LacY_symp PF01306.19 KZN87964.1 - 0.0014 17.5 16.5 0.23 10.2 4.5 3.3 3 0 0 3 3 3 3 LacY proton/sugar symporter Aldo_ket_red PF00248.21 KZN87965.1 - 1.1e-49 169.2 0.0 1.9e-49 168.4 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family CRAL_TRIO PF00650.20 KZN87966.1 - 7.5e-15 55.0 0.0 1.1e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KZN87966.1 - 7.3e-07 29.3 0.0 1.6e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Prok_Ub PF14454.6 KZN87966.1 - 0.039 13.6 0.0 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 Prokaryotic Ubiquitin CRAL_TRIO_2 PF13716.6 KZN87966.1 - 0.094 12.9 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain TAF6_C PF07571.13 KZN87967.1 - 7.5e-31 106.3 0.0 1.8e-30 105.1 0.0 1.7 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 KZN87967.1 - 5.3e-24 84.2 0.0 2e-23 82.3 0.1 1.9 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 KZN87967.1 - 5.6e-06 26.7 0.4 2.3e-05 24.7 0.3 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KZN87967.1 - 0.0054 16.8 0.1 0.013 15.6 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 KZN87967.1 - 0.049 13.9 0.9 0.11 12.7 0.1 2.0 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SAM_decarbox PF01536.16 KZN87968.1 - 3.7e-131 437.4 0.0 4.4e-131 437.1 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase TAFII28 PF04719.14 KZN87969.1 - 6.3e-25 87.1 2.0 1.5e-23 82.7 0.2 2.2 2 0 0 2 2 2 2 hTAFII28-like protein conserved region Baseplate_J PF04865.14 KZN87969.1 - 0.019 14.1 0.7 0.03 13.5 0.7 1.2 1 0 0 1 1 1 0 Baseplate J-like protein Acyl_transf_3 PF01757.22 KZN87970.1 - 2e-18 66.6 26.8 1e-17 64.2 26.8 2.1 1 1 0 1 1 1 1 Acyltransferase family 60KD_IMP PF02096.20 KZN87971.1 - 1.9e-23 83.2 0.5 3.5e-23 82.3 0.5 1.5 1 0 0 1 1 1 1 60Kd inner membrane protein FAM176 PF14851.6 KZN87971.1 - 0.31 10.7 4.4 36 4.0 0.0 3.0 3 0 0 3 3 3 0 FAM176 family TOM13 PF08219.11 KZN87972.1 - 2.6e-37 126.6 0.1 3.4e-37 126.3 0.1 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 MFS_1 PF07690.16 KZN87973.1 - 9.6e-41 139.9 29.1 9.6e-41 139.9 29.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KZN87973.1 - 1.5e-07 30.3 2.1 2.7e-07 29.4 2.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KZN87973.1 - 2.9e-05 23.1 27.0 0.00034 19.6 27.0 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 KZN87973.1 - 0.0017 17.7 3.3 0.0017 17.7 3.3 2.5 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB DUF3611 PF12263.8 KZN87973.1 - 0.11 12.3 2.2 0.2 11.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) TMCO5 PF14992.6 KZN87973.1 - 0.55 9.8 1.4 1.5 8.4 0.2 2.0 2 0 0 2 2 2 0 TMCO5 family FAD_binding_3 PF01494.19 KZN87974.1 - 4.5e-24 85.3 0.0 1.8e-23 83.3 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KZN87974.1 - 2.2e-07 30.8 0.7 3.9e-06 26.7 0.2 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KZN87974.1 - 3.7e-06 26.2 3.1 0.04 13.0 0.8 3.1 3 0 0 3 3 3 3 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KZN87974.1 - 6.2e-05 22.4 2.9 0.017 14.4 0.7 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN87974.1 - 0.00013 22.1 0.3 0.00031 20.9 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KZN87974.1 - 0.00025 20.2 0.5 0.00043 19.5 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KZN87974.1 - 0.00029 20.2 2.5 0.0014 17.9 0.2 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KZN87974.1 - 0.0063 15.9 0.2 1.7 7.9 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 KZN87974.1 - 0.013 14.4 0.0 0.038 12.8 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 KZN87974.1 - 0.022 14.0 0.3 0.038 13.2 0.3 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KZN87974.1 - 0.078 11.7 1.9 0.26 9.9 0.3 2.0 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 KZN87974.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 KZN87974.1 - 0.19 10.8 2.3 0.71 8.9 2.3 1.9 1 1 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KZN87974.1 - 0.61 10.1 2.1 21 5.0 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KZN87974.1 - 0.82 10.3 6.5 0.27 11.8 0.9 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase bZIP_1 PF00170.21 KZN87975.1 - 0.00047 20.2 1.3 0.00076 19.5 1.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor TBCC_N PF16752.5 KZN87975.1 - 0.081 13.4 0.6 0.17 12.4 0.6 1.4 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain Tropomyosin_1 PF12718.7 KZN87975.1 - 0.11 12.6 0.3 0.17 12.0 0.3 1.2 1 0 0 1 1 1 0 Tropomyosin like PLDc_2 PF13091.6 KZN87976.1 - 2.8e-16 59.6 0.1 7.7e-06 25.8 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.22 KZN87976.1 - 1.9e-13 49.9 1.8 2e-05 24.6 0.3 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Glyco_transf_20 PF00982.21 KZN87977.1 - 1.8e-157 524.8 0.0 2.1e-157 524.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 KZN87977.1 - 0.00083 18.9 0.0 0.037 13.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KZN87977.1 - 0.002 18.6 0.0 0.005 17.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KZN87977.1 - 0.034 14.5 0.1 0.12 12.8 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferases group 1 Hemerythrin PF01814.23 KZN87978.1 - 9.2e-13 49.0 0.0 1.3e-12 48.5 0.0 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Alpha_kinase PF02816.18 KZN87978.1 - 0.05 13.7 0.2 0.064 13.4 0.2 1.3 1 0 0 1 1 1 0 Alpha-kinase family ADH_N PF08240.12 KZN87979.1 - 1.8e-28 98.6 0.6 4.2e-28 97.4 0.4 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN87979.1 - 4.3e-22 78.5 0.0 8.1e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KZN87979.1 - 0.009 17.1 0.0 0.016 16.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.6 KZN87979.1 - 0.013 16.0 0.1 0.024 15.1 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KZN87979.1 - 0.017 14.4 0.1 0.023 14.0 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 KZN87979.1 - 0.02 15.2 0.1 0.064 13.5 0.1 1.9 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.6 KZN87979.1 - 0.031 13.5 0.5 0.045 13.0 0.5 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KZN87979.1 - 0.047 13.7 0.0 0.079 13.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Kinetochor_Ybp2 PF08568.10 KZN87980.1 - 1.2e-150 503.0 0.1 1.5e-150 502.7 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Rhomboid PF01694.22 KZN87981.1 - 2.2e-31 108.9 7.3 2.2e-31 108.9 7.3 1.8 3 0 0 3 3 3 1 Rhomboid family TauE PF01925.19 KZN87981.1 - 2.9 7.5 13.9 5.4 6.6 6.9 2.4 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE GRP PF07172.11 KZN87982.1 - 0.0071 17.0 5.7 0.0075 16.9 5.7 1.2 1 0 0 1 1 1 1 Glycine rich protein family DHHC PF01529.20 KZN87983.1 - 9.8e-38 129.3 7.6 2e-37 128.3 7.6 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase Yip1 PF04893.17 KZN87983.1 - 7.1 6.3 13.9 0.078 12.7 3.2 2.2 2 0 0 2 2 2 0 Yip1 domain UQ_con PF00179.26 KZN87984.1 - 8.4e-19 67.6 0.0 1.2e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KZN87984.1 - 0.064 13.5 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain BRE PF06113.12 KZN87984.1 - 0.14 11.0 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) CBP_BcsO PF17037.5 KZN87984.1 - 1 9.4 9.5 2.5 8.2 9.5 1.6 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO B-block_TFIIIC PF04182.12 KZN87985.1 - 8.5e-20 70.7 0.0 1.9e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC Fmp27 PF10344.9 KZN87987.1 - 1.1e-247 824.5 0.0 1.1e-247 824.5 0.0 2.4 3 0 0 3 3 3 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 KZN87987.1 - 1.2e-191 637.7 0.0 1.2e-191 637.7 0.0 4.2 4 0 0 4 4 4 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 KZN87987.1 - 3.2e-175 583.6 2.3 3.2e-175 583.6 2.3 2.1 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 KZN87987.1 - 3.5e-56 189.6 0.0 1.1e-55 188.0 0.0 1.9 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KZN87987.1 - 4.1e-54 182.7 0.1 9.1e-54 181.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 KZN87987.1 - 7.9e-30 103.6 0.1 1.1e-28 99.9 0.0 3.2 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain TraT PF05818.12 KZN87988.1 - 0.08 12.6 0.4 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein RRM_1 PF00076.22 KZN87989.1 - 4.3e-16 58.5 0.0 4.3e-16 58.5 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec2p PF06428.11 KZN87990.1 - 9.3e-10 38.4 10.8 9.3e-10 38.4 10.8 2.1 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p bZIP_1 PF00170.21 KZN87990.1 - 0.0054 16.8 13.0 0.032 14.3 0.1 3.4 2 1 1 3 3 3 2 bZIP transcription factor Jnk-SapK_ap_N PF09744.9 KZN87990.1 - 0.028 14.6 18.6 1.5 9.1 15.5 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Exonuc_VII_L PF02601.15 KZN87990.1 - 0.039 13.5 10.1 0.2 11.2 7.1 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit Spc7 PF08317.11 KZN87990.1 - 0.066 12.1 13.2 2.6 6.8 9.6 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein FAM76 PF16046.5 KZN87990.1 - 0.072 12.4 3.8 0.13 11.6 3.9 1.4 1 1 0 1 1 1 0 FAM76 protein LegC3_N PF18654.1 KZN87990.1 - 0.1 11.8 10.7 0.04 13.2 5.9 2.0 2 0 0 2 2 2 0 LegC3 N-terminal coiled-coil domain DUF2746 PF10874.8 KZN87990.1 - 0.2 12.1 0.1 0.42 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) YlqD PF11068.8 KZN87990.1 - 0.47 10.8 12.2 0.89 9.9 9.3 2.1 2 0 0 2 2 2 0 YlqD protein Cluap1 PF10234.9 KZN87990.1 - 1.3 8.3 14.0 1.1 8.6 11.7 1.8 2 0 0 2 2 2 0 Clusterin-associated protein-1 YabA PF06156.13 KZN87990.1 - 2 9.1 6.4 22 5.7 0.0 2.4 2 0 0 2 2 2 0 Initiation control protein YabA SlyX PF04102.12 KZN87990.1 - 2.6 8.7 15.4 9.5 6.9 0.0 4.0 2 1 2 4 4 4 0 SlyX COG2 PF06148.11 KZN87990.1 - 3.5 7.7 10.0 6.8 6.8 0.0 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HR1 PF02185.16 KZN87990.1 - 4.6 7.4 18.2 0.24 11.6 4.8 3.4 2 2 0 2 2 2 0 Hr1 repeat Ribosomal_L32e PF01655.18 KZN87991.1 - 4.4e-49 165.4 1.0 8.1e-49 164.5 1.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L32 GFO_IDH_MocA PF01408.22 KZN87991.1 - 2.7e-18 66.9 0.0 5.8e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KZN87991.1 - 0.0021 18.1 0.0 0.0051 16.8 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Fringe PF02434.16 KZN87992.1 - 9.2e-06 25.3 3.9 6.3e-05 22.5 0.1 3.1 3 1 0 3 3 3 1 Fringe-like PAN_4 PF14295.6 KZN87992.1 - 0.098 12.6 2.7 0.13 12.2 1.1 2.0 2 0 0 2 2 2 0 PAN domain PseudoU_synth_2 PF00849.22 KZN87993.1 - 4.8e-25 88.5 0.0 7.6e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 KZN87993.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 S4 domain GATA PF00320.27 KZN87995.1 - 0.096 12.3 12.3 0.32 10.6 0.1 3.7 4 0 0 4 4 4 0 GATA zinc finger DUF3795 PF12675.7 KZN87995.1 - 6.8 7.2 13.6 3.8 8.0 4.4 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF3795) ESM4 PF15952.5 KZN87996.1 - 0.00097 19.6 6.5 0.0012 19.3 6.5 1.3 1 0 0 1 1 1 1 Enhancer of split M4 family DUF5563 PF17718.1 KZN87996.1 - 3.9 7.0 8.5 6.1 6.4 8.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5563) Neur_chan_memb PF02932.16 KZN87996.1 - 7.1 6.6 6.0 7.9 6.5 6.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Aegerolysin PF06355.13 KZN87997.1 - 9.3e-26 90.5 0.2 1.1e-25 90.2 0.2 1.0 1 0 0 1 1 1 1 Aegerolysin FA_hydroxylase PF04116.13 KZN87998.1 - 0.0018 18.6 0.1 0.0035 17.7 0.1 1.5 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily 3Beta_HSD PF01073.19 KZN87998.1 - 0.038 13.0 0.0 0.048 12.7 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KZN87998.1 - 0.22 11.0 0.0 0.28 10.6 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Hexapep PF00132.24 KZN87999.1 - 2.2e-08 33.5 12.3 0.00049 19.7 0.8 3.5 1 1 4 5 5 5 5 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 KZN87999.1 - 7.3e-05 21.9 4.1 0.0003 19.9 4.1 1.9 1 1 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 KZN87999.1 - 0.014 13.5 0.6 0.02 13.0 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) 4HBT PF03061.22 KZN88000.1 - 6.5e-14 52.0 0.0 1.2e-13 51.2 0.0 1.4 1 1 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 KZN88000.1 - 6.4e-05 23.4 0.0 0.0001 22.8 0.0 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 KZN88000.1 - 0.00039 19.8 0.2 0.00059 19.2 0.2 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase RT_RNaseH_2 PF17919.1 KZN88001.1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase MFS_1 PF07690.16 KZN88003.1 - 8.7e-27 94.0 66.1 1.4e-21 76.8 42.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_zinc_N PF00107.26 KZN88004.1 - 1.2e-07 31.7 0.0 3.4e-07 30.3 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KZN88004.1 - 0.0032 18.5 0.0 0.0069 17.4 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KZN88004.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain AMP-binding PF00501.28 KZN88005.1 - 1.3e-159 531.3 0.0 7.5e-92 308.1 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KZN88005.1 - 9e-54 182.9 0.0 2.7e-28 98.9 0.0 2.3 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 KZN88005.1 - 5.1e-20 71.6 0.6 1.9e-09 37.7 0.0 3.2 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KZN88005.1 - 4.5e-16 59.6 0.1 4.3e-11 43.6 0.1 2.9 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Aa_trans PF01490.18 KZN88006.1 - 9.9e-30 103.6 25.0 1.4e-29 103.1 25.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sugar_tr PF00083.24 KZN88007.1 - 9.3e-120 400.5 27.8 1.1e-119 400.3 27.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN88007.1 - 7e-23 81.1 64.4 1e-20 74.0 29.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DnaJ_C PF01556.18 KZN88008.1 - 2.1e-36 125.2 0.2 3.4e-36 124.6 0.2 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KZN88008.1 - 1.8e-16 60.0 4.4 6.7e-16 58.2 4.4 2.0 1 1 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KZN88008.1 - 1.7e-13 50.7 20.7 2.9e-13 49.9 20.7 1.4 1 0 0 1 1 1 1 DnaJ central domain RseC_MucC PF04246.12 KZN88008.1 - 0.12 12.3 0.3 0.12 12.3 0.3 2.2 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF1356 PF07092.12 KZN88008.1 - 2.4 7.4 6.2 8.9 5.5 2.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) HypA PF01155.19 KZN88008.1 - 3 7.9 12.4 6 6.9 2.3 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_10 PF16685.5 KZN88008.1 - 6.8 6.9 10.9 2.5 8.3 0.7 2.2 1 1 0 2 2 2 0 zinc RING finger of MSL2 tRNA-synt_1c PF00749.21 KZN88009.1 - 2.7e-92 309.0 0.0 3.4e-92 308.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain MAP65_ASE1 PF03999.12 KZN88010.1 - 3e-75 254.1 0.1 4.4e-75 253.6 0.1 1.3 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) FAP206 PF12018.8 KZN88010.1 - 0.16 11.4 1.0 0.36 10.3 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF885 PF05960.11 KZN88010.1 - 0.21 11.2 3.0 0.13 11.9 0.5 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) LTXXQ PF07813.12 KZN88010.1 - 0.51 11.1 7.4 1.2 9.9 0.2 3.6 3 0 0 3 3 3 0 LTXXQ motif family protein DUF3080 PF11279.8 KZN88010.1 - 0.82 8.8 3.7 1.2 8.3 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3080) PEP-utilisers_N PF05524.13 KZN88010.1 - 1 9.6 3.6 9.1 6.5 0.2 3.0 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Occludin_ELL PF07303.13 KZN88010.1 - 2.2 9.0 4.3 3.4 8.5 0.0 3.2 2 2 0 2 2 2 0 Occludin homology domain Osmo_CC PF08946.10 KZN88010.1 - 9 6.6 6.7 18 5.7 0.3 3.7 3 0 0 3 3 3 0 Osmosensory transporter coiled coil JAB PF01398.21 KZN88011.1 - 1.6e-30 105.5 0.2 2.9e-30 104.6 0.2 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 KZN88011.1 - 6.8e-19 68.6 0.0 1.7e-18 67.3 0.0 1.7 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 KZN88011.1 - 8.9e-05 22.3 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain RasGEF PF00617.19 KZN88012.1 - 7.9e-59 198.8 0.0 1.4e-58 198.0 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KZN88012.1 - 7.8e-31 106.4 0.6 1.6e-30 105.5 0.6 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KZN88012.1 - 1.4e-14 53.4 0.2 1.4e-14 53.4 0.2 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KZN88012.1 - 5.7e-13 48.5 0.1 1.5e-12 47.2 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KZN88012.1 - 4.4e-11 42.3 0.1 1.7e-10 40.4 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain WW PF00397.26 KZN88012.1 - 0.007 16.4 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 WW domain Fungal_trans PF04082.18 KZN88013.1 - 6e-19 68.1 1.4 9.2e-19 67.5 1.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KZN88013.1 - 8.8e-07 29.1 14.9 7.4e-05 23.0 5.5 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KZN88013.1 - 0.00092 19.5 14.3 0.038 14.5 5.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KZN88013.1 - 0.002 18.8 12.6 0.26 12.3 4.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KZN88013.1 - 0.04 14.6 0.5 0.73 10.5 0.2 2.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 KZN88013.1 - 0.94 9.8 6.1 1.3 9.4 3.7 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KZN88013.1 - 1.6 8.9 3.7 5.6 7.2 3.7 2.0 1 0 0 1 1 1 0 Zinc ribbon domain UPRTase PF14681.6 KZN88014.1 - 5.6e-76 254.6 0.0 6.5e-76 254.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KZN88014.1 - 2.1e-06 27.3 0.1 5e-06 26.1 0.1 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain CRCB PF02537.15 KZN88015.1 - 6.1e-38 129.0 13.9 3.7e-22 78.5 6.9 2.5 2 1 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) THEG4 PF15834.5 KZN88016.1 - 0.54 10.2 1.5 0.95 9.4 1.5 1.6 1 1 0 1 1 1 0 Testis highly expressed protein 4 DUF3268 PF11672.8 KZN88018.1 - 6e-06 26.6 11.5 0.38 11.1 0.2 4.3 4 0 0 4 4 4 3 zinc-finger-containing domain mono-CXXC PF15626.6 KZN88018.1 - 0.0041 17.5 0.5 0.0041 17.5 0.5 3.0 4 0 0 4 4 4 1 single CXXC unit Terminase_GpA PF05876.12 KZN88018.1 - 7.3 5.0 19.5 0.46 9.0 0.2 3.7 2 2 1 4 4 4 0 Phage terminase large subunit (GpA) DZR PF12773.7 KZN88018.1 - 7.5 6.7 38.9 4.5 7.4 2.6 6.6 1 1 3 4 4 4 0 Double zinc ribbon RNA_pol_Rpc4 PF05132.14 KZN88019.1 - 1.4e-33 116.5 0.1 1.4e-33 116.5 0.1 4.0 2 2 2 4 4 4 1 RNA polymerase III RPC4 Zn_clus PF00172.18 KZN88020.1 - 0.0027 17.8 12.5 0.005 16.9 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.10 KZN88020.1 - 0.12 11.9 0.1 0.33 10.5 0.1 1.8 1 0 0 1 1 1 0 Histone chaperone domain CHZ Cyclin_N PF00134.23 KZN88022.1 - 2.8e-42 143.5 0.1 6.6e-42 142.2 0.1 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KZN88022.1 - 3.8e-33 114.1 0.0 7.7e-33 113.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain HA2 PF04408.23 KZN88023.1 - 2.3e-18 66.5 0.2 5.1e-17 62.1 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KZN88023.1 - 9e-16 58.0 0.0 1.8e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RWD PF05773.22 KZN88023.1 - 3.4e-14 53.1 0.0 8.1e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 RWD domain Helicase_C PF00271.31 KZN88023.1 - 3.2e-13 50.0 0.0 7e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KZN88023.1 - 8e-10 38.8 0.0 1.5e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 KZN88023.1 - 0.0055 15.8 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein dsRBD2 PF17842.1 KZN88023.1 - 0.0056 16.9 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding domain 2 AAA_22 PF13401.6 KZN88023.1 - 0.01 16.1 2.8 0.29 11.4 2.8 2.5 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KZN88023.1 - 0.014 14.9 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_29 PF13555.6 KZN88023.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 KZN88023.1 - 0.037 13.4 0.1 0.073 12.4 0.1 1.4 1 0 0 1 1 1 0 KaiC DND1_DSRM PF14709.7 KZN88023.1 - 0.097 12.9 0.1 0.097 12.9 0.1 2.0 2 0 0 2 2 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 ResIII PF04851.15 KZN88023.1 - 0.12 12.4 0.0 0.36 10.8 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_23 PF13476.6 KZN88023.1 - 0.17 12.4 0.1 0.17 12.4 0.1 1.7 2 0 0 2 2 1 0 AAA domain zf-C2HE PF16278.5 KZN88024.1 - 6.6e-20 71.3 0.0 1.6e-19 70.1 0.0 1.7 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 KZN88024.1 - 3.9e-17 62.8 4.6 4.1e-16 59.5 4.6 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KZN88024.1 - 4.8e-17 62.5 0.1 1.1e-16 61.4 0.1 1.6 1 1 0 1 1 1 1 HIT domain TRAP_alpha PF03896.16 KZN88025.1 - 1.8e-15 56.9 0.0 3.1e-15 56.1 0.0 1.3 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit zf-CCCH_2 PF14608.6 KZN88026.1 - 0.08 13.4 0.2 0.08 13.4 0.2 3.2 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger POT1PC PF16686.5 KZN88027.1 - 2e-37 128.4 0.2 8.5e-36 123.2 0.0 2.4 2 0 0 2 2 2 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 KZN88027.1 - 5.2e-20 71.8 0.0 1e-19 70.8 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.25 KZN88027.1 - 0.0031 17.5 0.0 0.14 12.1 0.0 2.5 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Arm PF00514.23 KZN88028.1 - 1e-91 298.5 13.5 4.1e-14 52.0 0.0 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KZN88028.1 - 5.2e-27 94.1 4.9 1.3e-26 92.9 4.9 1.7 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 KZN88028.1 - 8.7e-24 82.8 3.7 1.9e-23 81.8 3.7 1.6 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 KZN88028.1 - 6.6e-20 71.2 6.7 1.3e-08 35.2 0.0 6.3 5 2 2 7 7 7 3 HEAT-like repeat HEAT_2 PF13646.6 KZN88028.1 - 7.2e-18 64.8 0.1 6.8e-08 32.8 0.0 5.0 1 1 3 5 5 5 3 HEAT repeats HEAT PF02985.22 KZN88028.1 - 3.8e-16 57.8 0.7 3.5e-06 26.8 0.0 7.0 7 0 0 7 7 7 3 HEAT repeat Arm_2 PF04826.13 KZN88028.1 - 1.7e-08 34.2 0.0 0.0022 17.5 0.0 3.9 2 1 2 4 4 4 2 Armadillo-like V-ATPase_H_C PF11698.8 KZN88028.1 - 7.9e-05 22.8 0.0 1.5 9.0 0.0 4.6 4 1 0 4 4 4 1 V-ATPase subunit H HEAT_PBS PF03130.16 KZN88028.1 - 0.027 15.1 1.2 1.5 9.8 0.0 4.1 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Gcn1_N PF12074.8 KZN88028.1 - 0.058 12.7 0.0 8.7 5.5 0.0 2.3 2 0 0 2 2 2 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal RICTOR_V PF14668.6 KZN88028.1 - 0.11 12.7 3.8 1.5 9.1 0.0 4.3 4 2 1 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 STAG PF08514.11 KZN88029.1 - 1.7e-40 137.4 6.1 2.8e-39 133.5 2.9 2.9 2 0 0 2 2 2 2 STAG domain MIF4G PF02854.19 KZN88029.1 - 0.012 15.3 0.1 0.074 12.7 0.0 2.3 3 0 0 3 3 3 0 MIF4G domain Cob_adeno_trans PF01923.18 KZN88029.1 - 1.2 9.3 7.2 6.4 6.9 0.1 3.6 3 1 0 3 3 3 0 Cobalamin adenosyltransferase UreD PF01774.17 KZN88030.1 - 3.6e-77 259.1 0.0 5e-77 258.6 0.0 1.2 1 0 0 1 1 1 1 UreD urease accessory protein S1 PF00575.23 KZN88032.1 - 9.7e-69 227.7 23.8 8e-16 58.2 0.9 12.2 12 0 0 12 12 12 9 S1 RNA binding domain Suf PF05843.14 KZN88032.1 - 5.8e-08 33.1 14.4 0.0033 17.4 0.0 5.3 3 1 2 5 5 5 3 Suppressor of forked protein (Suf) TPR_19 PF14559.6 KZN88032.1 - 1.6e-06 28.5 0.0 0.016 15.7 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KZN88032.1 - 2.2e-05 24.9 6.4 0.65 11.0 0.6 6.0 3 1 4 7 7 7 1 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 KZN88032.1 - 0.00015 21.7 0.0 20 5.2 0.0 5.7 5 0 0 5 5 5 0 RNase II-type exonuclease C-terminal S1 domain Mad3_BUB1_I PF08311.12 KZN88032.1 - 0.0017 18.4 0.2 0.0031 17.5 0.2 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 TPR_15 PF13429.6 KZN88032.1 - 0.0047 16.2 1.9 0.71 9.0 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat PPR PF01535.20 KZN88032.1 - 0.019 15.2 0.2 12 6.4 0.0 3.6 3 0 0 3 3 3 0 PPR repeat S1_2 PF13509.6 KZN88032.1 - 0.038 14.0 0.4 18 5.5 0.0 4.2 4 0 0 4 4 4 0 S1 domain PPR_2 PF13041.6 KZN88032.1 - 0.067 13.4 0.0 36 4.7 0.0 3.4 3 0 0 3 3 3 0 PPR repeat family WD40 PF00400.32 KZN88033.1 - 8.1e-17 61.3 3.3 0.00013 22.7 0.1 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN88033.1 - 7.5e-08 32.6 0.0 0.028 14.7 0.0 4.9 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Met_asp_mut_E PF06368.11 KZN88033.1 - 0.23 9.9 0.0 0.36 9.3 0.0 1.1 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) ORC6 PF05460.13 KZN88033.1 - 4.3 6.5 10.1 7.3 5.8 10.1 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Cpn60_TCP1 PF00118.24 KZN88035.1 - 4.8e-150 500.4 18.0 5.5e-150 500.2 18.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ProRS-C_1 PF09180.11 KZN88036.1 - 1.5e-22 79.6 1.8 3.6e-22 78.4 1.8 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 KZN88036.1 - 1.1e-18 67.8 0.0 1.8e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KZN88036.1 - 5.4e-10 39.3 0.0 2.5e-09 37.2 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain MecA_N PF05223.11 KZN88036.1 - 0.87 9.9 4.7 61 3.9 2.1 3.4 3 0 0 3 3 3 0 NTF2-like N-terminal transpeptidase domain RNase_PH PF01138.21 KZN88038.1 - 1.3e-30 106.6 0.1 2.6e-30 105.6 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 PEMT PF04191.13 KZN88039.1 - 9.3e-58 193.2 14.5 3e-37 127.2 0.6 3.0 3 0 0 3 3 3 2 Phospholipid methyltransferase SKICH PF17751.1 KZN88039.1 - 0.0035 17.9 0.1 0.058 13.9 0.1 2.3 1 1 0 1 1 1 1 SKICH domain HECW_N PF16562.5 KZN88039.1 - 0.0093 15.8 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 Kinesin PF00225.23 KZN88040.1 - 4.1e-58 196.9 0.6 1.4e-32 112.9 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 KZN88040.1 - 1.8e-11 44.2 0.0 3.7e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding ParA PF10609.9 KZN88041.1 - 5.4e-97 324.1 0.0 6.4e-97 323.8 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KZN88041.1 - 2.4e-08 34.1 0.0 1e-07 32.1 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KZN88041.1 - 3.6e-06 26.4 0.5 0.00018 20.8 0.0 2.6 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_31 PF13614.6 KZN88041.1 - 1.1e-05 25.4 0.0 0.00011 22.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_26 PF13500.6 KZN88041.1 - 0.0025 17.7 0.1 0.67 9.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 KZN88041.1 - 0.015 14.6 0.0 0.036 13.3 0.0 1.6 1 1 0 1 1 1 0 ATPase MipZ RsgA_GTPase PF03193.16 KZN88041.1 - 0.017 15.0 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Fer4_NifH PF00142.18 KZN88041.1 - 0.029 13.8 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_30 PF13604.6 KZN88041.1 - 0.034 13.8 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 KZN88041.1 - 0.037 13.8 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_25 PF13481.6 KZN88041.1 - 0.045 13.3 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KZN88041.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 KZN88041.1 - 0.19 12.1 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 KZN88041.1 - 0.19 11.7 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 KZN88041.1 - 0.22 10.7 0.0 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Jacalin PF01419.17 KZN88042.1 - 0.0019 18.1 0.2 0.0034 17.3 0.2 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain Helo_like_N PF17111.5 KZN88044.1 - 4.7e-05 22.9 5.1 7.3e-05 22.2 5.1 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 KZN88044.1 - 0.0064 16.7 1.6 0.0064 16.7 1.6 1.8 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NusB PF01029.18 KZN88044.1 - 0.32 11.2 2.7 1.1 9.5 0.3 2.3 2 0 0 2 2 2 0 NusB family SNARE PF05739.19 KZN88046.1 - 3.2e-08 33.5 0.9 6.4e-08 32.5 0.9 1.5 1 0 0 1 1 1 1 SNARE domain DUF4407 PF14362.6 KZN88046.1 - 0.0073 15.7 3.7 0.053 12.9 3.7 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) Use1 PF09753.9 KZN88046.1 - 0.033 13.9 0.6 0.1 12.3 0.6 1.9 1 1 0 1 1 1 0 Membrane fusion protein Use1 Snapin_Pallidin PF14712.6 KZN88046.1 - 0.037 14.5 2.9 0.84 10.1 0.1 2.8 2 1 0 2 2 2 0 Snapin/Pallidin ABC_tran_CTD PF16326.5 KZN88046.1 - 0.047 13.9 0.3 0.047 13.9 0.3 2.4 3 0 0 3 3 3 0 ABC transporter C-terminal domain HrpB7 PF09486.10 KZN88046.1 - 0.081 13.3 0.6 0.081 13.3 0.6 2.7 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) Synaptobrevin PF00957.21 KZN88046.1 - 0.15 11.8 0.9 0.4 10.5 0.9 1.8 1 0 0 1 1 1 0 Synaptobrevin XhlA PF10779.9 KZN88046.1 - 0.53 10.5 9.2 3.6 7.9 7.2 3.0 2 1 0 2 2 2 0 Haemolysin XhlA zf-TRAF PF02176.18 KZN88047.1 - 4.6e-13 49.6 16.5 5.1e-09 36.7 3.0 4.0 1 1 3 4 4 4 4 TRAF-type zinc finger zf-TRAF_2 PF15965.5 KZN88047.1 - 1e-07 32.3 11.2 1e-07 32.3 11.2 3.1 1 1 1 3 3 3 1 TRAF-like zinc-finger zf-RING_UBOX PF13445.6 KZN88047.1 - 2.2e-07 30.8 10.5 9.1e-07 28.8 10.5 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KZN88047.1 - 5e-07 29.5 10.5 5e-07 29.5 10.5 3.3 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KZN88047.1 - 3.1e-06 27.2 13.3 3.1e-06 27.2 13.3 2.7 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KZN88047.1 - 9e-06 25.9 11.6 9e-06 25.9 11.6 3.6 3 1 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 KZN88047.1 - 6e-05 22.9 9.9 6e-05 22.9 9.9 3.3 2 1 1 3 3 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KZN88047.1 - 0.00022 21.0 9.1 0.00022 21.0 9.1 3.6 2 1 2 4 4 3 1 Zinc finger, C3HC4 type (RING finger) TraP PF07296.11 KZN88047.1 - 0.037 13.2 0.6 0.076 12.2 0.6 1.4 1 0 0 1 1 1 0 TraP protein CCDC158 PF15921.5 KZN88047.1 - 0.047 11.5 0.2 0.4 8.5 0.0 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 158 zf-C3HC4_2 PF13923.6 KZN88047.1 - 6.1 6.8 28.2 0.028 14.3 11.8 4.1 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 KZN88047.1 - 8.9 6.2 18.0 2.6 8.0 3.1 2.7 1 1 1 2 2 2 0 Seven in absentia protein family Fungal_trans PF04082.18 KZN88048.1 - 1e-13 51.0 0.2 1.7e-13 50.2 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN88048.1 - 4.4e-11 42.7 5.9 9.2e-11 41.7 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PBP_N PF17093.5 KZN88050.1 - 0.23 11.7 4.3 21 5.3 4.6 2.2 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus Het-C PF07217.11 KZN88051.1 - 3.4e-277 920.5 0.0 5e-277 920.0 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C PhyH PF05721.13 KZN88052.1 - 4.1e-10 40.3 0.3 1e-09 39.0 0.3 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Zn_clus PF00172.18 KZN88053.1 - 2.7e-09 37.0 7.5 4.1e-09 36.4 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SlyX PF04102.12 KZN88053.1 - 0.31 11.7 2.8 0.59 10.8 2.8 1.4 1 0 0 1 1 1 0 SlyX Methyltransf_23 PF13489.6 KZN88054.1 - 8.4e-21 74.5 0.0 1.3e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN88054.1 - 1.7e-11 44.7 0.0 5.9e-11 42.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN88054.1 - 2.9e-08 33.7 0.0 5.5e-07 29.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN88054.1 - 3.1e-08 34.1 0.0 7.8e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN88054.1 - 4.7e-08 33.7 0.0 2e-07 31.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KZN88054.1 - 0.0012 18.3 0.0 0.0036 16.8 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 KZN88054.1 - 0.0026 17.9 0.0 0.0061 16.7 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.14 KZN88054.1 - 0.012 15.2 0.0 0.19 11.3 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain UPF0146 PF03686.13 KZN88054.1 - 0.019 14.8 0.0 4.2 7.3 0.0 2.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0146) Ubie_methyltran PF01209.18 KZN88054.1 - 0.022 14.1 0.0 0.36 10.1 0.0 2.2 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KZN88054.1 - 0.037 13.3 0.0 0.089 12.1 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 KZN88054.1 - 0.084 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase IBN_N PF03810.19 KZN88055.1 - 2.4e-08 33.8 0.2 3.6e-07 30.0 0.1 3.1 2 1 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KZN88055.1 - 0.0003 20.9 1.1 0.037 14.1 0.0 4.1 4 1 0 4 4 4 1 Exportin 1-like protein Proteasom_PSMB PF10508.9 KZN88055.1 - 0.00063 18.4 0.0 0.17 10.3 0.0 2.5 2 0 0 2 2 2 2 Proteasome non-ATPase 26S subunit CAS_CSE1 PF03378.15 KZN88055.1 - 0.00096 17.8 0.0 0.0023 16.5 0.0 1.6 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus RIX1 PF08167.12 KZN88055.1 - 0.0033 17.2 0.0 0.027 14.2 0.0 2.6 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis GNAT_like PF18407.1 KZN88055.1 - 0.039 14.3 1.1 1.3 9.4 0.0 3.3 3 0 0 3 3 3 0 GCN5-related N-acetyltransferase like domain RICTOR_N PF14664.6 KZN88055.1 - 0.35 9.8 2.9 0.44 9.5 1.1 2.0 2 1 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term HORMA PF02301.18 KZN88056.1 - 4e-11 42.9 0.0 5.1e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 HORMA domain Acetyltransf_7 PF13508.7 KZN88057.1 - 5.6e-06 26.7 0.0 1.1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KZN88057.1 - 0.00029 21.1 0.0 0.00081 19.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KZN88057.1 - 0.00036 20.6 0.1 0.0015 18.6 0.0 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KZN88057.1 - 0.00051 20.0 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KZN88057.1 - 0.013 15.0 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase FR47 PF08445.10 KZN88057.1 - 0.02 14.9 0.0 0.05 13.6 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein Dcc1 PF09724.9 KZN88058.1 - 2.4e-23 83.0 0.0 3e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Anp1 PF03452.14 KZN88059.1 - 4.7e-112 373.7 0.0 6.6e-112 373.2 0.0 1.2 1 0 0 1 1 1 1 Anp1 Rad54_N PF08658.10 KZN88059.1 - 0.076 13.2 0.9 0.15 12.2 0.9 1.4 1 0 0 1 1 1 0 Rad54 N terminal KR PF08659.10 KZN88060.1 - 1.9e-09 37.7 0.0 2.9e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KZN88060.1 - 2.4e-08 33.7 0.0 3.3e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KZN88060.1 - 0.016 14.6 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 KZN88060.1 - 0.048 13.2 0.0 0.067 12.7 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 KZN88060.1 - 0.058 12.8 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ADH_N PF08240.12 KZN88061.1 - 2.4e-26 91.7 0.1 4.4e-26 90.9 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN88061.1 - 5.1e-24 84.7 0.9 7.4e-24 84.2 0.9 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KZN88061.1 - 1.2e-05 25.1 0.3 4.5e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.6 KZN88061.1 - 0.0011 20.0 0.1 0.0018 19.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase bZIP_1 PF00170.21 KZN88062.1 - 2.4e-05 24.3 7.5 3.6e-05 23.8 7.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KZN88062.1 - 0.00016 22.1 4.8 0.00025 21.5 4.8 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 KZN88062.1 - 0.00025 21.1 8.7 0.00037 20.5 8.7 1.2 1 0 0 1 1 1 1 Basic region leucine zipper DUF3432 PF11914.8 KZN88062.1 - 0.022 15.0 7.0 0.022 15.0 7.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3432) Ank_2 PF12796.7 KZN88063.1 - 6.2e-28 97.2 0.6 5.5e-11 42.9 0.0 4.1 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN88063.1 - 1.1e-21 76.9 0.1 6.1e-05 23.5 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KZN88063.1 - 7.4e-18 64.1 0.5 0.00094 19.5 0.0 6.6 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 KZN88063.1 - 1.2e-15 56.0 0.2 0.26 11.9 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 KZN88063.1 - 6.1e-15 55.1 3.3 0.025 14.9 0.1 6.4 4 2 1 6 6 6 5 Ankyrin repeats (many copies) F-box-like PF12937.7 KZN88063.1 - 3.1e-06 27.0 1.5 5.2e-05 23.1 0.2 2.9 2 1 1 3 3 3 1 F-box-like F-box PF00646.33 KZN88063.1 - 0.0037 17.1 0.1 0.011 15.6 0.1 1.9 1 0 0 1 1 1 1 F-box domain Ank_2 PF12796.7 KZN88064.1 - 5.7e-23 81.3 0.0 1.9e-07 31.6 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN88064.1 - 1.5e-21 76.5 0.1 5.8e-07 29.9 0.0 4.3 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KZN88064.1 - 4.3e-15 55.4 1.5 0.00067 20.0 0.1 5.8 6 1 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 KZN88064.1 - 1.4e-13 49.7 0.6 0.003 17.9 0.0 6.2 6 1 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 KZN88064.1 - 2.5e-12 46.8 0.9 0.0048 17.2 0.2 5.3 2 1 4 6 6 6 5 Ankyrin repeats (many copies) tRNA_bind PF01588.20 KZN88065.1 - 7.1e-22 77.3 0.0 5.8e-21 74.4 0.0 2.2 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 KZN88065.1 - 0.00016 21.7 0.0 0.00029 20.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KZN88065.1 - 0.021 15.0 0.0 0.021 15.0 0.0 2.2 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KZN88065.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ferlin_C PF16165.5 KZN88065.1 - 2.2 8.2 4.9 3.6 7.5 4.9 1.3 1 0 0 1 1 1 0 Ferlin C-terminus Asp PF00026.23 KZN88066.1 - 1.3e-59 202.2 0.1 2e-59 201.6 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KZN88066.1 - 1.3e-08 35.3 0.7 0.0003 21.1 0.1 3.0 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KZN88066.1 - 7.9e-06 26.4 0.1 0.14 12.8 0.1 2.9 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KZN88066.1 - 2.1e-05 25.0 0.0 0.18 12.4 0.0 2.8 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KZN88066.1 - 0.027 14.2 0.0 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal DUF4452 PF14618.6 KZN88067.1 - 2.1e-72 242.5 9.0 2.9e-72 242.0 9.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) Cyclin_N PF00134.23 KZN88068.1 - 1.6e-10 40.8 0.0 8.4e-10 38.5 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KZN88068.1 - 0.097 13.1 0.7 0.37 11.2 0.2 2.2 2 1 0 2 2 2 0 Cyclin C-terminal domain Mito_carr PF00153.27 KZN88069.1 - 5.2e-68 225.0 4.2 5.3e-22 77.5 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 KZN88069.1 - 1.2e-21 74.5 3.3 7.6e-06 25.1 0.1 4.5 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 KZN88069.1 - 1.1e-20 73.8 3.8 5.4e-12 46.0 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KZN88069.1 - 4.7e-18 63.5 6.7 8.5e-05 22.2 0.1 4.6 3 1 1 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KZN88069.1 - 2.2e-17 61.7 4.9 0.0001 21.6 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KZN88069.1 - 1.2e-11 44.2 1.6 6.4e-05 22.7 0.1 3.3 2 2 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KZN88069.1 - 1.5e-07 31.7 0.0 0.0012 19.2 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region GST_N_2 PF13409.6 KZN88070.1 - 4e-24 84.7 0.0 9.5e-24 83.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KZN88070.1 - 4.2e-18 65.1 0.1 1.1e-17 63.8 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KZN88070.1 - 1e-07 32.1 0.0 1.8e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KZN88070.1 - 1.1e-05 25.7 0.3 0.00073 19.9 0.1 2.7 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KZN88070.1 - 0.0001 22.4 0.0 0.0002 21.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KZN88070.1 - 0.0013 19.3 0.0 0.0021 18.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KZN88070.1 - 0.0024 17.6 0.0 0.0058 16.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain QIL1 PF15884.5 KZN88070.1 - 0.089 13.4 0.0 0.4 11.3 0.0 2.0 2 0 0 2 2 2 0 MICOS complex subunit MIC13, QIL1 ThiF PF00899.21 KZN88071.1 - 3.9e-110 367.0 0.0 3.2e-73 246.1 0.0 2.3 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KZN88071.1 - 4e-97 325.1 0.3 2e-96 322.8 0.2 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 KZN88071.1 - 3.4e-31 107.8 0.1 6.8e-31 106.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 KZN88071.1 - 3.3e-30 104.1 0.2 6.8e-30 103.1 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 KZN88071.1 - 8.5e-26 89.9 0.6 2.5e-25 88.4 0.6 1.9 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle GCP_N_terminal PF17681.1 KZN88072.1 - 1.3e-34 120.3 0.0 2.1e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KZN88072.1 - 6.1e-19 68.6 0.0 1.7e-18 67.1 0.0 1.7 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal Sema PF01403.19 KZN88072.1 - 0.22 10.3 0.0 0.33 9.7 0.0 1.2 1 0 0 1 1 1 0 Sema domain adh_short_C2 PF13561.6 KZN88073.1 - 7.3e-54 182.8 0.1 9.5e-54 182.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN88073.1 - 1.5e-45 155.1 0.1 2e-45 154.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN88073.1 - 1.6e-14 54.2 0.2 2.4e-14 53.6 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KZN88073.1 - 0.00045 19.8 0.1 0.00093 18.7 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family HATPase_c PF02518.26 KZN88073.1 - 0.0072 16.8 0.0 0.013 16.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NAD_binding_2 PF03446.15 KZN88073.1 - 0.045 13.9 0.0 0.2 11.8 0.0 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Glu_dehyd_C PF16912.5 KZN88073.1 - 0.14 11.6 0.0 0.41 10.1 0.0 1.8 1 1 0 1 1 1 0 Glucose dehydrogenase C-terminus DEAD PF00270.29 KZN88074.1 - 1.3e-17 64.2 0.0 2.6e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KZN88074.1 - 5.9e-12 45.9 0.0 2.5e-11 43.9 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KZN88074.1 - 4.8e-06 26.9 0.0 1.8e-05 25.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.16 KZN88074.1 - 0.091 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein CVNH PF08881.10 KZN88075.1 - 1.1e-10 42.1 0.5 1.3e-10 41.9 0.5 1.0 1 0 0 1 1 1 1 CVNH domain FAD_binding_4 PF01565.23 KZN88077.1 - 8.5e-20 70.9 0.0 1.7e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KZN88077.1 - 2.9e-09 36.9 0.3 6.9e-09 35.7 0.3 1.6 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.16 KZN88078.1 - 3.4e-35 121.6 25.9 3.4e-35 121.6 25.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily TssN PF17555.2 KZN88078.1 - 1 8.7 8.2 0.033 13.6 0.5 2.0 2 0 0 2 2 2 0 Type VI secretion system, TssN C5-epim_C PF06662.13 KZN88079.1 - 0.0044 16.5 0.5 0.05 13.1 0.1 2.1 2 0 0 2 2 2 1 D-glucuronyl C5-epimerase C-terminus WbqC PF08889.11 KZN88079.1 - 0.071 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 WbqC-like protein family GILT PF03227.16 KZN88080.1 - 3.4e-12 46.5 1.1 3.4e-12 46.5 1.1 2.5 2 1 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Hexokinase_1 PF00349.21 KZN88081.1 - 1.6e-60 204.4 0.0 2.2e-60 204.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 KZN88081.1 - 9.3e-49 166.0 0.0 5.4e-47 160.2 0.0 2.8 2 1 0 2 2 2 1 Hexokinase Occludin_ELL PF07303.13 KZN88082.1 - 0.025 15.3 1.1 0.035 14.8 1.1 1.2 1 0 0 1 1 1 0 Occludin homology domain TFIIA_gamma_C PF02751.14 KZN88083.1 - 8.2e-26 89.9 2.7 1.5e-25 89.1 2.7 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 KZN88083.1 - 3.1e-23 81.5 0.1 4.2e-23 81.1 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Dabb PF07876.12 KZN88086.1 - 2e-22 79.6 0.0 2.2e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain TPR_12 PF13424.6 KZN88087.1 - 1.1e-13 51.3 9.2 3.4e-06 27.3 0.1 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KZN88087.1 - 4.2e-05 24.0 3.9 2.4 8.7 0.4 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KZN88087.1 - 0.0018 17.7 5.1 0.0044 16.5 3.7 2.1 1 1 1 2 2 2 1 MalT-like TPR region TPR_14 PF13428.6 KZN88087.1 - 0.0022 18.7 10.1 12 7.0 0.1 5.9 4 2 2 6 6 6 1 Tetratricopeptide repeat SNAP PF14938.6 KZN88087.1 - 0.021 14.3 0.1 0.035 13.5 0.1 1.3 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_16 PF13432.6 KZN88087.1 - 0.026 15.2 5.8 1.6 9.4 0.4 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KZN88087.1 - 0.027 14.6 7.5 3.4 8.0 0.0 5.2 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 KZN88087.1 - 0.08 13.2 2.3 24 5.5 0.1 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KZN88087.1 - 0.17 11.8 13.4 1.7 8.6 0.2 4.8 5 1 1 6 6 6 0 Tetratricopeptide repeat LigT_PEase PF02834.16 KZN88088.1 - 0.0014 18.8 0.0 0.012 15.7 0.0 2.2 2 0 0 2 2 2 1 LigT like Phosphoesterase Aldedh PF00171.22 KZN88089.1 - 2e-130 435.4 0.1 2.2e-130 435.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KZN88089.1 - 6.8e-05 22.1 0.0 0.00015 21.0 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) ATP-synt_D PF01813.17 KZN88089.1 - 0.0068 16.3 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase subunit D YfdX PF10938.8 KZN88089.1 - 0.34 10.8 2.4 0.32 10.9 0.2 2.0 2 0 0 2 2 2 0 YfdX protein DnaB_bind PF10410.9 KZN88089.1 - 0.42 10.8 1.8 1.4 9.1 0.1 2.5 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase Methyltransf_33 PF10017.9 KZN88090.1 - 1.4e-82 277.3 0.0 2.1e-82 276.8 0.0 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 KZN88090.1 - 1.1e-19 71.0 1.3 2.1e-19 70.1 1.3 1.4 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KZN88090.1 - 8.3e-07 29.6 1.3 2.4e-06 28.1 1.3 1.9 1 0 0 1 1 1 1 DinB superfamily MscS_porin PF12795.7 KZN88091.1 - 0.013 15.1 0.4 0.019 14.5 0.4 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain TMF_DNA_bd PF12329.8 KZN88091.1 - 0.14 12.1 1.7 0.23 11.5 1.7 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding PKcGMP_CC PF16808.5 KZN88091.1 - 0.6 10.0 3.3 0.45 10.4 0.6 2.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4807 PF16065.5 KZN88092.1 - 0.036 13.7 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4807) Astro_capsid_p PF12226.8 KZN88092.1 - 0.18 11.0 4.3 0.29 10.3 4.3 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein PHO4 PF01384.20 KZN88093.1 - 7.5e-103 344.1 18.4 8.8e-103 343.9 18.4 1.0 1 0 0 1 1 1 1 Phosphate transporter family UPF0444 PF15475.6 KZN88093.1 - 0.5 10.7 8.7 0.78 10.1 0.7 3.0 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 PgpA PF04608.13 KZN88093.1 - 3.7 7.6 8.0 0.63 10.1 0.8 2.9 3 0 0 3 3 3 0 Phosphatidylglycerophosphatase A 7TMR-DISM_7TM PF07695.11 KZN88093.1 - 5.9 6.7 14.8 5.6 6.8 0.2 3.8 3 2 0 3 3 3 0 7TM diverse intracellular signalling Cation_ATPase_C PF00689.21 KZN88094.1 - 2.6e-45 154.4 7.9 2.6e-45 154.4 7.9 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KZN88094.1 - 1.3e-36 125.8 0.1 1.3e-36 125.8 0.1 3.0 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase PF13246.6 KZN88094.1 - 3.8e-19 68.6 0.0 7.4e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KZN88094.1 - 4.3e-17 63.1 1.2 2.3e-16 60.7 1.2 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KZN88094.1 - 6.6e-06 25.7 0.3 7.4e-05 22.4 0.0 2.8 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus LptF_LptG PF03739.14 KZN88094.1 - 0.0025 16.7 2.9 0.0025 16.7 2.9 1.9 2 0 0 2 2 2 1 Lipopolysaccharide export system permease LptF/LptG Hydrolase_3 PF08282.12 KZN88094.1 - 0.04 13.7 0.1 0.073 12.8 0.1 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DevR PF01905.16 KZN88094.1 - 0.058 12.4 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 DUF1774 PF08611.10 KZN88094.1 - 0.65 10.4 9.5 3.9 7.9 1.8 3.6 3 0 0 3 3 3 0 Fungal protein of unknown function (DUF1774) PrgI PF12666.7 KZN88094.1 - 1.7 9.4 5.1 19 6.1 0.1 3.6 3 0 0 3 3 3 0 PrgI family protein TPR_10 PF13374.6 KZN88095.1 - 1.1e-85 279.4 2.4 1.8e-12 46.7 0.0 8.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.6 KZN88095.1 - 6.2e-68 225.1 18.8 1.8e-14 53.8 0.0 7.0 2 2 4 7 7 7 7 Tetratricopeptide repeat TPR_MalT PF17874.1 KZN88095.1 - 4.3e-18 65.8 8.4 4.3e-11 42.8 1.1 2.4 1 1 1 2 2 2 2 MalT-like TPR region TPR_7 PF13176.6 KZN88095.1 - 1.9e-17 61.9 11.7 0.013 15.5 0.0 7.8 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_4 PF07721.14 KZN88095.1 - 8.6e-15 53.8 8.5 0.0025 18.3 0.0 6.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KZN88095.1 - 2.9e-14 52.0 6.4 0.034 14.3 0.0 7.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 KZN88095.1 - 3.3e-14 52.0 1.4 0.16 11.9 0.0 7.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 KZN88095.1 - 1.5e-12 46.6 6.1 0.4 11.0 0.1 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 KZN88095.1 - 3.8e-09 36.3 9.0 3.8 8.1 0.0 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 KZN88095.1 - 4.7e-09 36.8 8.0 0.31 11.7 0.6 6.1 5 2 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KZN88095.1 - 1.2e-07 32.1 6.4 10 6.7 0.0 6.5 4 3 2 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 KZN88095.1 - 5.9e-07 29.8 12.3 0.7 10.9 0.2 6.5 7 1 0 7 7 5 2 Tetratricopeptide repeat DUF4919 PF16266.5 KZN88095.1 - 3.3e-05 23.9 0.2 0.089 12.7 0.0 4.2 2 2 4 6 6 6 1 Domain of unknown function (DUF4919) TPR_6 PF13174.6 KZN88095.1 - 0.0078 16.8 17.8 2.8 8.8 0.0 6.7 8 1 0 8 8 7 2 Tetratricopeptide repeat PPR PF01535.20 KZN88095.1 - 0.012 15.9 0.1 4.6 7.7 0.0 4.2 4 0 0 4 4 4 0 PPR repeat DUF1897 PF09005.10 KZN88095.1 - 0.045 13.2 2.6 34 4.0 0.1 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF1897) Tautomerase PF01361.21 KZN88095.1 - 0.14 12.2 0.1 14 5.7 0.0 2.8 2 0 0 2 2 2 0 Tautomerase enzyme Wzy_C_2 PF11846.8 KZN88095.1 - 0.3 11.0 2.1 6.1 6.7 0.0 3.4 3 1 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal Na_Ca_ex PF01699.24 KZN88096.1 - 9.4e-17 61.4 28.2 2.7e-10 40.4 14.8 2.0 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Na_Ca_ex PF01699.24 KZN88097.1 - 1.1e-19 70.9 26.3 1.7e-11 44.3 8.4 2.4 2 1 0 2 2 2 2 Sodium/calcium exchanger protein Fig1 PF12351.8 KZN88097.1 - 5.8 6.8 10.9 0.35 10.7 1.2 2.9 3 0 0 3 3 3 0 Ca2+ regulator and membrane fusion protein Fig1 Na_Ca_ex PF01699.24 KZN88098.1 - 9.6e-38 129.5 34.9 8.4e-20 71.3 12.2 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein MscL PF01741.18 KZN88098.1 - 0.38 11.1 4.2 1.2 9.4 0.2 3.0 2 1 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL Rab5ip PF07019.12 KZN88098.1 - 7.4 7.2 9.4 0.66 10.6 2.2 2.8 3 0 0 3 3 3 0 Rab5-interacting protein (Rab5ip) TMEM154 PF15102.6 KZN88099.1 - 1.9e-05 24.6 1.5 2e-05 24.5 1.5 1.1 1 0 0 1 1 1 1 TMEM154 protein family SP_C-Propep PF08999.10 KZN88099.1 - 9.5e-05 22.1 0.1 0.00012 21.8 0.1 1.2 1 0 0 1 1 1 1 Surfactant protein C, N terminal propeptide ASFV_J13L PF05568.11 KZN88099.1 - 0.00012 21.9 0.1 0.00013 21.7 0.1 1.1 1 0 0 1 1 1 1 African swine fever virus J13L protein EphA2_TM PF14575.6 KZN88099.1 - 0.0053 17.6 0.0 0.0056 17.5 0.0 1.1 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain RCR PF12273.8 KZN88099.1 - 0.0087 16.7 0.3 0.01 16.4 0.3 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF3377 PF11857.8 KZN88099.1 - 0.026 14.4 1.3 0.035 14.0 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) FeoB_associated PF12669.7 KZN88099.1 - 0.032 14.6 2.0 0.045 14.1 2.0 1.1 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein YajC PF02699.15 KZN88099.1 - 0.046 13.6 0.2 0.058 13.3 0.2 1.1 1 0 0 1 1 1 0 Preprotein translocase subunit Baculo_11_kDa PF06143.11 KZN88099.1 - 0.05 13.2 1.1 0.066 12.8 1.1 1.1 1 0 0 1 1 1 0 Baculovirus 11 kDa family ECSCR PF15820.5 KZN88099.1 - 0.063 13.1 0.7 0.075 12.9 0.7 1.1 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator SIT PF15330.6 KZN88099.1 - 0.098 13.1 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF2207 PF09972.9 KZN88099.1 - 0.19 10.5 0.4 0.21 10.3 0.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) OSTbeta PF15048.6 KZN88099.1 - 0.19 11.8 0.2 0.26 11.5 0.2 1.1 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Stevor PF17410.2 KZN88099.1 - 0.42 10.1 4.2 0.52 9.8 4.2 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame ODV-E18 PF10717.9 KZN88099.1 - 1.3 9.0 3.8 1.7 8.5 3.8 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 RIFIN PF02009.16 KZN88099.1 - 2.1 8.2 8.3 2.5 7.9 8.3 1.0 1 0 0 1 1 1 0 Rifin DUF92 PF01940.16 KZN88101.1 - 9.2e-83 277.3 11.4 1.1e-82 277.0 11.4 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Fungal_trans PF04082.18 KZN88102.1 - 4.2e-39 134.2 0.0 7e-39 133.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN88102.1 - 2.6e-09 37.1 9.0 4.3e-09 36.3 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KZN88102.1 - 0.03 13.1 0.0 0.061 12.1 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain RNA_pol PF00940.19 KZN88104.1 - 5.2e-183 608.6 0.0 7e-183 608.2 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KZN88104.1 - 2.1e-91 306.8 0.2 3.9e-91 305.9 0.2 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Sin_N PF04801.13 KZN88105.1 - 1.2e-27 97.2 0.2 3.9e-27 95.5 0.2 1.6 1 1 0 1 1 1 1 Sin-like protein conserved region MFS_1 PF07690.16 KZN88108.1 - 9.1e-38 130.1 20.0 9.1e-38 130.1 20.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KZN88108.1 - 0.00099 18.1 1.2 0.00099 18.1 1.2 2.1 2 1 1 3 3 3 1 MFS_1 like family GHMP_kinases_N PF00288.26 KZN88108.1 - 0.035 14.3 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 GHMP kinases N terminal domain SpoVAB PF13782.6 KZN88108.1 - 7.4 6.9 10.6 0.2 11.9 0.8 2.7 3 0 0 3 3 3 0 Stage V sporulation protein AB PTP_tm PF18861.1 KZN88109.1 - 0.0065 16.5 0.0 0.0086 16.1 0.0 1.2 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J Abhydrolase_3 PF07859.13 KZN88110.1 - 2.4e-28 99.4 0.0 3.1e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KZN88110.1 - 7.8e-14 51.3 0.0 2.7e-13 49.5 0.0 1.7 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KZN88110.1 - 0.0057 16.2 0.0 0.034 13.6 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.28 KZN88110.1 - 0.17 10.7 0.1 0.33 9.8 0.0 1.4 2 0 0 2 2 2 0 Carboxylesterase family NIR_SIR PF01077.22 KZN88111.1 - 1.1e-51 174.5 0.0 5.6e-45 152.7 0.0 2.7 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KZN88111.1 - 1.9e-27 94.9 0.0 5.8e-13 48.5 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 KZN88111.1 - 2.9e-26 92.4 0.0 5.9e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 KZN88111.1 - 1.5e-07 31.4 0.0 3.2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Kei1 PF08552.11 KZN88112.1 - 6.8e-69 231.6 2.5 8.2e-69 231.3 2.5 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 MmgE_PrpD PF03972.14 KZN88113.1 - 4.2e-131 437.5 5.8 4.7e-131 437.3 5.8 1.0 1 0 0 1 1 1 1 MmgE/PrpD family AAA_29 PF13555.6 KZN88113.1 - 0.087 12.6 0.9 0.52 10.1 0.2 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF1174 PF06671.11 KZN88113.1 - 0.094 12.4 0.4 0.25 11.1 0.4 1.7 1 0 0 1 1 1 0 Repeat of unknown function (DUF1174) Ras PF00071.22 KZN88114.1 - 2.7e-59 199.4 0.2 3.4e-59 199.1 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KZN88114.1 - 4.5e-37 126.9 0.5 7.8e-37 126.2 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KZN88114.1 - 1.3e-17 63.8 0.1 1.6e-17 63.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KZN88114.1 - 1.4e-06 28.3 0.2 0.00097 19.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KZN88114.1 - 4.4e-06 26.4 0.1 2.9e-05 23.7 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KZN88114.1 - 5.9e-06 25.8 0.0 8.7e-06 25.3 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KZN88114.1 - 1.4e-05 25.1 0.0 2.4e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KZN88114.1 - 4.1e-05 23.1 0.2 5.3e-05 22.7 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TIR_2 PF13676.6 KZN88114.1 - 0.085 13.5 0.0 0.15 12.7 0.0 1.4 1 0 0 1 1 1 0 TIR domain AAA_7 PF12775.7 KZN88114.1 - 0.088 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP-synt_C PF00137.21 KZN88115.1 - 3.1e-25 88.3 27.5 3.8e-14 52.8 11.1 2.4 2 0 0 2 2 2 2 ATP synthase subunit C Oxidored_q2 PF00420.24 KZN88115.1 - 3.5 7.3 8.7 1.3 8.7 3.1 2.9 2 1 1 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L MoCF_biosynth PF00994.24 KZN88116.1 - 6.8e-46 155.5 0.0 7.2e-23 80.8 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 KZN88116.1 - 8.9e-40 136.0 2.0 1.7e-39 135.1 2.0 1.5 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 KZN88116.1 - 4e-14 52.5 0.2 1.2e-13 51.0 0.2 1.9 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) NicO PF03824.16 KZN88116.1 - 1.6 8.0 5.4 2.5 7.4 5.4 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein SelP_N PF04592.14 KZN88116.1 - 2.4 7.5 15.8 3.7 6.9 15.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DDHD PF02862.17 KZN88117.1 - 1.1e-25 91.2 0.1 9.6e-15 55.3 0.0 2.9 2 1 0 3 3 3 2 DDHD domain DUF5613 PF18467.1 KZN88118.1 - 0.037 14.4 0.1 0.1 13.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5613) DUF3909 PF13077.6 KZN88118.1 - 0.14 12.3 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3909) FAD_binding_3 PF01494.19 KZN88119.1 - 3.8e-72 243.4 0.0 4.8e-72 243.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KZN88119.1 - 3.2e-38 131.4 0.0 6.5e-38 130.4 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 KZN88119.1 - 0.018 14.3 0.0 0.06 12.6 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KZN88119.1 - 0.018 14.6 0.0 0.17 11.4 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KZN88119.1 - 0.048 13.9 0.0 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KZN88119.1 - 0.05 14.2 0.0 0.15 12.6 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KZN88119.1 - 0.081 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.12 KZN88119.1 - 0.14 11.1 0.0 0.41 9.6 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein DUF866 PF05907.13 KZN88120.1 - 2.6e-63 212.6 0.3 3e-63 212.4 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Paired_CXXCH_1 PF09699.10 KZN88120.1 - 0.13 12.0 0.2 0.13 12.0 0.2 1.7 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrom_c3_2 PF14537.6 KZN88120.1 - 0.49 10.9 4.1 0.97 9.9 3.0 1.9 1 1 1 2 2 2 0 Cytochrome c3 HalOD2 PF18547.1 KZN88120.1 - 1.8 8.5 5.3 14 5.7 5.4 2.1 1 1 0 1 1 1 0 Halobacterial output domain 2 DUF4379 PF14311.6 KZN88120.1 - 9.2 6.7 9.3 0.23 11.9 0.7 2.7 3 1 1 4 4 4 0 Probable Zinc-ribbon domain LSM PF01423.22 KZN88121.1 - 7.5e-19 67.2 0.0 8.7e-19 67.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain CoxIIa PF08113.11 KZN88121.1 - 0.049 13.4 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family DUF4576 PF15144.6 KZN88122.1 - 0.14 12.0 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) RTA1 PF04479.13 KZN88123.1 - 8.2e-67 224.8 10.0 8.2e-67 224.8 10.0 1.4 2 0 0 2 2 2 1 RTA1 like protein Cation_ATPase_C PF00689.21 KZN88123.1 - 0.47 10.1 15.9 0.35 10.5 3.6 2.6 2 1 0 3 3 3 0 Cation transporting ATPase, C-terminus OapA_N PF08525.11 KZN88123.1 - 1.8 8.6 0.0 1.8 8.6 0.0 3.0 3 0 0 3 3 3 0 Opacity-associated protein A N-terminal motif DASH_Dad1 PF08649.10 KZN88124.1 - 4.6e-26 90.8 4.6 5.9e-26 90.4 4.6 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 KZN88124.1 - 0.022 14.7 0.1 0.032 14.2 0.1 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad4 V_ATPase_I PF01496.19 KZN88124.1 - 0.17 9.8 0.1 0.19 9.6 0.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ras PF00071.22 KZN88125.1 - 1.4e-48 164.5 0.0 1.8e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KZN88125.1 - 5.3e-21 75.0 0.0 8.3e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KZN88125.1 - 3.2e-05 23.4 0.0 0.00019 20.9 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 KZN88125.1 - 0.036 13.6 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 KZN88125.1 - 0.048 13.1 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PAP2 PF01569.21 KZN88126.1 - 9e-17 61.1 3.2 9e-17 61.1 3.2 2.1 3 0 0 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.6 KZN88126.1 - 0.0011 18.7 6.1 0.0011 18.7 6.1 1.8 2 0 0 2 2 2 1 PAP2 superfamily Peptidase_C48 PF02902.19 KZN88127.1 - 8.2e-25 87.9 0.0 1.6e-24 87.0 0.0 1.4 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain zf-HIT PF04438.16 KZN88128.1 - 1.8e-10 40.5 9.6 1.8e-10 40.5 9.6 1.6 2 0 0 2 2 2 1 HIT zinc finger Btz PF09405.10 KZN88128.1 - 0.035 14.4 0.0 0.079 13.2 0.0 1.5 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding zf-MYND PF01753.18 KZN88128.1 - 0.53 10.4 7.8 1.1 9.5 7.8 1.5 1 0 0 1 1 1 0 MYND finger adh_short PF00106.25 KZN88129.1 - 2.6e-25 89.1 0.0 3.2e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN88129.1 - 2.2e-22 79.8 0.0 2.8e-22 79.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN88129.1 - 1.8e-06 28.0 0.0 2.5e-06 27.5 0.0 1.3 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KZN88129.1 - 0.00054 19.4 0.0 0.00064 19.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) MlaE PF02405.16 KZN88129.1 - 0.13 11.9 0.1 0.28 10.8 0.1 1.5 1 0 0 1 1 1 0 Permease MlaE DAO PF01266.24 KZN88131.1 - 3.2e-29 102.6 0.1 3.7e-29 102.4 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Malic_M PF03949.15 KZN88131.1 - 0.039 13.2 0.1 1.1 8.5 0.1 2.1 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Glu_dehyd_C PF16912.5 KZN88131.1 - 0.1 12.0 0.0 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus DUF267 PF03268.14 KZN88131.1 - 0.19 10.6 0.0 0.27 10.1 0.0 1.1 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF267 DFRP_C PF16543.5 KZN88132.1 - 9.5e-23 80.5 6.9 9.5e-23 80.5 6.9 3.8 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 KZN88132.1 - 2.3e-05 24.1 2.9 2.3e-05 24.1 2.9 2.8 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KZN88132.1 - 0.00021 21.0 10.4 0.0029 17.3 2.9 3.3 3 0 0 3 3 3 1 CCCH-type zinc finger Torus PF16131.5 KZN88132.1 - 0.00037 21.2 5.4 0.00037 21.2 5.4 3.9 2 2 2 4 4 4 2 Torus domain zf_CCCH_4 PF18345.1 KZN88132.1 - 0.0054 16.7 7.4 0.0054 16.7 7.4 3.3 4 0 0 4 4 4 1 Zinc finger domain zf-CCCH_3 PF15663.5 KZN88132.1 - 0.12 12.6 6.4 0.44 10.8 0.2 2.9 3 0 0 3 3 3 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 KZN88132.1 - 0.33 11.5 14.8 0.45 11.1 4.7 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger CS PF04969.16 KZN88133.1 - 3e-07 31.3 0.0 4.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 CS domain Snf7 PF03357.21 KZN88134.1 - 2.9e-21 75.8 11.7 2.9e-21 75.8 11.7 1.7 1 1 1 2 2 2 1 Snf7 PSD4 PF07631.11 KZN88134.1 - 0.024 15.2 1.7 0.068 13.7 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1592) Gon7 PF08738.10 KZN88134.1 - 0.043 13.9 7.4 0.086 12.9 4.4 2.3 2 1 0 2 2 2 0 Gon7 family BMFP PF04380.13 KZN88134.1 - 0.12 12.9 10.3 0.71 10.4 1.5 3.9 2 1 1 3 3 3 0 Membrane fusogenic activity Fib_alpha PF08702.10 KZN88134.1 - 1.5 9.0 11.1 1.1 9.4 5.2 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Tnp_P_element_C PF12596.8 KZN88134.1 - 3 8.4 5.7 21 5.7 0.1 2.7 2 1 1 3 3 3 0 87kDa Transposase TPR_MLP1_2 PF07926.12 KZN88134.1 - 5.2 7.2 19.1 0.033 14.3 5.7 3.2 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 KZN88134.1 - 6.7 7.1 13.8 2.3e+02 2.1 13.8 2.1 1 1 0 1 1 1 0 Fez1 RRM_1 PF00076.22 KZN88135.1 - 6.1e-15 54.8 0.0 1.1e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KZN88135.1 - 2.1e-05 25.0 1.8 2.1e-05 25.0 1.8 2.8 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 KZN88135.1 - 6.7e-05 22.7 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_7 PF16367.5 KZN88135.1 - 0.026 14.6 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif NAM-associated PF14303.6 KZN88135.1 - 2.6 8.8 6.6 0.29 11.8 1.7 1.8 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain EF-hand_8 PF13833.6 KZN88136.1 - 0.0089 15.9 0.0 0.28 11.0 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 KZN88136.1 - 0.017 15.0 0.1 0.97 9.5 0.0 3.3 4 0 0 4 4 4 0 EF-hand domain EF-hand_9 PF14658.6 KZN88136.1 - 0.08 13.3 0.0 13 6.2 0.0 2.6 2 1 0 2 2 2 0 EF-hand domain RuvA_C PF07499.13 KZN88136.1 - 0.11 13.0 0.0 0.34 11.4 0.0 1.9 1 1 0 1 1 1 0 RuvA, C-terminal domain PUL PF08324.11 KZN88137.1 - 1.1e-65 221.6 0.5 1.6e-65 221.1 0.5 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 KZN88137.1 - 9.2e-34 116.4 0.0 1.7e-33 115.6 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 KZN88137.1 - 5.4e-15 55.2 0.0 1.1e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KZN88137.1 - 0.00011 22.5 0.4 0.0034 17.8 0.4 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 KZN88137.1 - 0.00023 21.1 0.0 0.00037 20.4 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 KZN88137.1 - 0.0046 17.0 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.21 KZN88137.1 - 0.0051 16.7 0.0 0.0091 15.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KZN88137.1 - 0.049 13.4 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Redoxin Glutaredoxin PF00462.24 KZN88137.1 - 0.18 12.1 0.0 0.47 10.7 0.0 1.8 1 0 0 1 1 1 0 Glutaredoxin 2-Hacid_dh_C PF02826.19 KZN88138.1 - 4e-37 127.3 0.0 6e-37 126.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KZN88138.1 - 9.9e-21 73.8 0.0 1.4e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.12 KZN88138.1 - 0.0062 16.1 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 KZN88138.1 - 0.015 15.4 3.1 0.018 15.1 0.7 2.3 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 KZN88138.1 - 0.21 11.5 1.5 4.5 7.1 0.1 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2020 PF09449.10 KZN88139.1 - 0.098 12.5 0.4 0.6 9.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2020) F-box-like PF12937.7 KZN88140.1 - 0.03 14.2 0.1 0.081 12.8 0.1 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KZN88140.1 - 0.041 13.8 0.4 0.11 12.4 0.4 1.7 1 0 0 1 1 1 0 F-box domain Alb1 PF09135.11 KZN88141.1 - 4.4e-32 111.1 14.1 6.2e-32 110.6 14.1 1.2 1 0 0 1 1 1 1 Alb1 Vps16_N PF04841.13 KZN88142.1 - 4.8e-98 328.6 0.0 6.4e-98 328.2 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 KZN88142.1 - 6.3e-89 298.2 0.0 1.2e-88 297.3 0.0 1.4 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 KZN88142.1 - 0.0016 18.7 0.0 0.19 12.0 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain CREPT PF16566.5 KZN88142.1 - 0.018 15.2 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour AAA_lid_2 PF17863.1 KZN88143.1 - 6.3e-08 32.4 0.0 1.7e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 AAA lid domain Bestrophin PF01062.21 KZN88144.1 - 2.7e-57 194.4 0.0 3.4e-57 194.1 0.0 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel FHA PF00498.26 KZN88146.1 - 9.9e-14 51.5 0.0 1.8e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 KZN88146.1 - 2.4e-10 39.9 4.2 4.7e-10 39.0 4.2 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KZN88146.1 - 2.7e-07 30.8 8.3 6e-07 29.7 8.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KZN88146.1 - 0.00041 20.2 6.0 0.00079 19.3 6.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Yop-YscD_cpl PF16697.5 KZN88146.1 - 0.00056 20.2 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4_2 PF13923.6 KZN88146.1 - 0.0083 16.0 8.8 0.017 15.0 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KZN88146.1 - 0.021 14.7 7.4 0.053 13.4 7.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KZN88146.1 - 0.043 14.1 8.3 0.14 12.5 8.3 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KZN88146.1 - 0.044 13.8 2.8 0.097 12.7 2.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 KZN88146.1 - 0.049 14.0 4.8 0.12 12.7 4.8 1.7 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 KZN88146.1 - 0.14 12.1 5.6 0.3 11.0 5.6 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 KZN88146.1 - 0.67 10.2 6.9 1.5 9.0 6.4 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KZN88146.1 - 1.8 8.2 7.9 4.3 7.0 7.9 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Arm PF00514.23 KZN88147.1 - 1.7e-74 243.8 28.3 2.9e-13 49.3 0.1 11.4 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KZN88147.1 - 3.5e-18 65.7 11.5 3.6e-05 24.2 0.1 8.3 8 2 1 9 9 9 5 HEAT-like repeat HEAT_2 PF13646.6 KZN88147.1 - 3.8e-17 62.5 8.1 0.0026 18.1 0.0 6.8 3 3 2 6 6 6 4 HEAT repeats HEAT PF02985.22 KZN88147.1 - 4.4e-16 57.6 13.7 0.31 11.4 0.0 9.0 10 0 0 10 10 8 5 HEAT repeat Arm_2 PF04826.13 KZN88147.1 - 2.5e-12 46.8 4.2 1.6e-07 31.1 1.0 2.5 1 1 1 2 2 2 2 Armadillo-like Adaptin_N PF01602.20 KZN88147.1 - 2.2e-11 43.0 5.4 1.1e-06 27.6 0.4 2.7 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.12 KZN88147.1 - 5.4e-10 38.1 0.4 9.3e-10 37.3 0.4 1.3 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 KZN88147.1 - 1.1e-09 38.0 0.4 6.8e-05 22.3 0.7 3.1 2 1 1 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.7 KZN88147.1 - 1.1e-05 25.5 6.3 0.04 14.0 0.1 5.0 2 1 3 6 6 6 2 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 KZN88147.1 - 4.6e-05 23.4 5.5 1.6 8.7 0.0 4.1 1 1 3 4 4 4 3 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 KZN88147.1 - 0.00029 20.9 1.6 16 5.7 0.0 5.0 2 1 6 8 8 7 0 V-ATPase subunit H IFRD PF05004.13 KZN88147.1 - 0.0039 16.4 6.3 1.5 7.9 0.3 4.4 3 2 1 4 4 4 2 Interferon-related developmental regulator (IFRD) Atx10homo_assoc PF09759.9 KZN88147.1 - 0.0067 16.4 6.7 1.4 9.0 0.4 4.8 3 2 2 5 5 5 1 Spinocerebellar ataxia type 10 protein domain HEAT_PBS PF03130.16 KZN88147.1 - 0.021 15.5 5.4 27 5.8 0.3 6.1 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat UNC45-central PF11701.8 KZN88147.1 - 0.022 14.7 1.5 1.7 8.6 0.3 3.3 2 1 1 3 3 3 0 Myosin-binding striated muscle assembly central Vac14_Fab1_bd PF12755.7 KZN88147.1 - 0.035 14.7 0.0 2.3 8.9 0.0 3.5 2 1 2 4 4 3 0 Vacuolar 14 Fab1-binding region EXOSC1 PF10447.9 KZN88148.1 - 1.3e-28 99.8 4.1 1.9e-28 99.3 4.1 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 KZN88148.1 - 4.8e-11 42.3 0.3 9e-11 41.4 0.3 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region DUF5567 PF17722.1 KZN88148.1 - 0.056 13.3 0.2 0.056 13.3 0.2 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5567) GTP_EFTU PF00009.27 KZN88149.1 - 3.3e-58 196.4 0.0 5.4e-58 195.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KZN88149.1 - 2.4e-15 56.3 0.0 5.9e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KZN88149.1 - 3.7e-09 36.8 0.0 3.9e-08 33.6 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KZN88149.1 - 5.1e-07 29.7 0.0 1.4e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 KZN88149.1 - 0.0031 17.3 0.0 0.011 15.5 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 KZN88149.1 - 0.079 13.0 0.0 0.22 11.6 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF4604 PF15377.6 KZN88150.1 - 4.3e-19 69.6 17.7 4.9e-19 69.4 17.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) WD40 PF00400.32 KZN88151.1 - 7.7e-14 51.9 5.7 0.00016 22.4 0.0 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN88151.1 - 2.7e-13 50.0 0.0 6.4e-06 26.4 0.0 4.5 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KZN88151.1 - 7.8e-08 32.0 0.0 2.9e-05 23.5 0.0 2.5 2 1 0 3 3 3 2 WD40-like domain Coatomer_WDAD PF04053.14 KZN88151.1 - 1.7e-07 30.7 0.1 0.0097 15.0 0.0 2.2 1 1 1 2 2 2 2 Coatomer WD associated region eIF2A PF08662.11 KZN88151.1 - 1.7e-05 24.8 0.0 0.048 13.5 0.0 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KZN88151.1 - 0.015 13.7 0.0 0.4 8.9 0.0 2.0 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KZN88151.1 - 0.028 13.4 0.2 0.11 11.5 0.1 1.9 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KZN88151.1 - 0.097 11.2 0.6 1.2 7.6 0.2 2.3 1 1 2 3 3 3 0 Cytochrome D1 heme domain Glyoxal_oxid_N PF07250.11 KZN88151.1 - 0.13 11.4 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus Bactofilin PF04519.13 KZN88151.1 - 0.13 12.5 3.0 0.35 11.2 3.0 1.8 1 0 0 1 1 1 0 Polymer-forming cytoskeletal PQQ_3 PF13570.6 KZN88151.1 - 2.4 8.7 7.1 2.3 8.8 0.3 3.5 3 0 0 3 3 3 0 PQQ-like domain zf-RING_UBOX PF13445.6 KZN88152.1 - 0.00027 20.9 2.6 0.00052 20.0 2.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KZN88152.1 - 0.00057 20.2 1.7 0.0011 19.3 1.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KZN88152.1 - 0.004 17.0 2.3 0.013 15.3 2.3 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KZN88152.1 - 0.0077 16.3 2.2 0.013 15.6 2.2 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-RING_5 PF14634.6 KZN88152.1 - 0.01 15.8 5.3 0.017 15.0 5.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KZN88152.1 - 0.043 13.7 5.7 0.11 12.4 5.7 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KZN88152.1 - 0.066 13.1 3.4 0.18 11.7 3.4 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KZN88152.1 - 0.066 13.1 6.0 0.52 10.2 5.7 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 IBR PF01485.21 KZN88152.1 - 1.1 9.6 6.5 4 7.7 1.2 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain L51_S25_CI-B8 PF05047.16 KZN88153.1 - 1.7e-15 56.7 0.1 2.4e-15 56.2 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain U1snRNP70_N PF12220.8 KZN88154.1 - 7.5e-26 90.6 4.1 1.5e-25 89.7 4.1 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 KZN88154.1 - 4.2e-16 58.5 0.1 7.5e-16 57.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KZN88154.1 - 0.00043 20.3 0.0 0.00087 19.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif RL10P_insert PF17777.1 KZN88155.1 - 2e-20 72.6 0.0 3.8e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KZN88155.1 - 9.9e-19 67.3 0.0 2.2e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 MDM10 PF12519.8 KZN88156.1 - 6.9e-150 500.0 1.5 2.9e-128 428.7 2.7 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 TIM PF00121.18 KZN88157.1 - 7.2e-91 303.9 0.9 8.1e-91 303.7 0.9 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 KZN88157.1 - 0.028 13.9 0.1 0.041 13.3 0.1 1.3 1 0 0 1 1 1 0 CutC family Pkinase PF00069.25 KZN88158.1 - 1.5e-09 37.6 0.1 7.8e-05 22.2 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KZN88158.1 - 8.3e-06 25.3 0.2 0.0001 21.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 KZN88158.1 - 0.0018 17.9 0.1 0.0037 16.9 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Snf7 PF03357.21 KZN88159.1 - 2.4e-27 95.6 28.5 1e-13 51.2 13.8 2.8 2 1 1 3 3 3 2 Snf7 RepB_primase PF16793.5 KZN88159.1 - 0.036 14.2 0.6 0.085 13.0 0.0 1.8 2 0 0 2 2 2 0 RepB DNA-primase from phage plasmid YlqD PF11068.8 KZN88159.1 - 0.76 10.1 15.4 3.3 8.1 6.8 2.2 2 0 0 2 2 2 0 YlqD protein OmpH PF03938.14 KZN88159.1 - 5.1 7.4 13.2 1.6 9.0 5.0 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Dynamin_N PF00350.23 KZN88160.1 - 2.9e-17 63.2 0.1 6.9e-17 62.0 0.1 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KZN88160.1 - 5.1e-10 39.4 0.0 3.2e-09 36.9 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KZN88160.1 - 9.3e-07 28.6 0.3 3.9e-05 23.3 0.2 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IIGP PF05049.13 KZN88160.1 - 0.046 12.8 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Sigma54_activat PF00158.26 KZN88160.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain cobW PF02492.19 KZN88160.1 - 0.068 12.8 0.1 2.5 7.7 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 KZN88160.1 - 0.069 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KZN88160.1 - 0.077 13.6 0.0 0.31 11.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain DUF883 PF05957.13 KZN88160.1 - 0.099 13.2 1.7 73 4.1 0.3 4.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) AAA_29 PF13555.6 KZN88160.1 - 0.15 11.8 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Baculo_PEP_C PF04513.12 KZN88160.1 - 0.16 12.0 0.7 1.8 8.6 0.1 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PTCB-BRCT PF12738.7 KZN88161.1 - 5.1e-50 167.3 1.0 7.9e-24 83.4 0.1 4.4 5 0 0 5 5 5 3 twin BRCT domain BRCT PF00533.26 KZN88161.1 - 8.4e-31 106.2 0.4 4e-15 56.0 0.1 4.6 4 1 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KZN88161.1 - 8.8e-17 61.3 0.0 7.1e-06 26.3 0.0 4.4 4 0 0 4 4 4 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KZN88161.1 - 2e-07 31.2 5.0 0.0016 18.7 0.1 4.3 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 KZN88161.1 - 0.0015 18.6 0.0 1.9 8.6 0.0 3.5 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain PIF1 PF05970.14 KZN88162.1 - 9.8e-66 222.4 0.1 8.1e-51 173.3 0.0 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KZN88162.1 - 2.8e-23 82.7 0.0 4.5e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KZN88162.1 - 2e-11 44.4 0.0 3.4e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KZN88162.1 - 1.6e-06 28.5 0.0 4.3e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KZN88162.1 - 4.5e-05 23.8 0.3 0.035 14.5 0.0 2.8 2 1 0 2 2 2 1 RNA helicase Herpes_Helicase PF02689.14 KZN88162.1 - 6.4e-05 21.1 0.0 0.001 17.1 0.0 2.5 3 0 0 3 3 3 1 Helicase AAA_7 PF12775.7 KZN88162.1 - 0.00017 21.2 0.0 0.00033 20.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region UvrD_C_2 PF13538.6 KZN88162.1 - 0.0018 18.1 0.1 0.0058 16.4 0.1 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 KZN88162.1 - 0.0029 18.0 0.0 0.0086 16.5 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KZN88162.1 - 0.004 17.6 0.0 0.0086 16.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KZN88162.1 - 0.009 15.3 0.1 0.023 13.9 0.1 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 KZN88162.1 - 0.015 15.8 0.1 0.41 11.2 0.1 3.0 2 1 0 2 2 2 0 ABC transporter PhoH PF02562.16 KZN88162.1 - 0.021 14.3 0.2 0.079 12.4 0.1 1.9 1 1 1 2 2 2 0 PhoH-like protein SH3_13 PF18335.1 KZN88162.1 - 0.023 14.5 0.1 0.068 13.0 0.1 1.8 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain NB-ARC PF00931.22 KZN88162.1 - 0.026 13.7 0.1 0.046 12.9 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 KZN88162.1 - 0.036 14.0 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 KZN88162.1 - 0.045 13.7 0.1 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 KZN88162.1 - 0.049 13.4 0.0 4.1 7.1 0.0 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TrwB_AAD_bind PF10412.9 KZN88162.1 - 0.055 12.4 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF5605 PF18310.1 KZN88162.1 - 0.062 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5605) ResIII PF04851.15 KZN88162.1 - 0.07 13.1 1.2 0.23 11.4 0.9 2.0 1 1 2 3 3 3 0 Type III restriction enzyme, res subunit AAA_5 PF07728.14 KZN88162.1 - 0.17 11.9 0.5 2.1 8.4 0.5 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Helicase_RecD PF05127.14 KZN88162.1 - 0.17 11.7 0.3 0.81 9.5 0.3 2.0 1 1 0 1 1 1 0 Helicase AAA_11 PF13086.6 KZN88162.1 - 0.2 11.4 0.0 0.2 11.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain UvrD-helicase PF00580.21 KZN88162.1 - 0.31 10.5 4.1 0.13 11.7 0.2 2.1 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain YjeF_N PF03853.15 KZN88163.1 - 2.2e-43 148.1 0.2 3.3e-43 147.5 0.2 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 KZN88163.1 - 2.2e-07 31.7 0.3 2.2e-07 31.7 0.3 2.1 2 0 0 2 2 2 1 FDF domain NTP_transferase PF00483.23 KZN88163.1 - 0.18 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase F-box-like PF12937.7 KZN88166.1 - 3.2e-05 23.7 0.2 6.9e-05 22.7 0.2 1.6 1 0 0 1 1 1 1 F-box-like PalH PF08733.10 KZN88167.1 - 2.5e-109 365.3 0.1 3.3e-109 364.9 0.1 1.1 1 0 0 1 1 1 1 PalH/RIM21 Asp PF00026.23 KZN88168.1 - 2.2e-73 247.4 7.7 3e-73 247.0 7.7 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KZN88168.1 - 7.4e-08 32.8 2.1 7.2e-05 23.1 1.5 3.1 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KZN88168.1 - 0.00033 21.2 0.8 0.048 14.3 0.2 2.9 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 KZN88168.1 - 0.019 14.7 0.0 0.047 13.5 0.0 1.7 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Zn_clus PF00172.18 KZN88169.1 - 5.4e-07 29.6 14.8 8.3e-07 29.0 14.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PriC PF07445.12 KZN88169.1 - 0.06 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Primosomal replication protein priC Atg14 PF10186.9 KZN88170.1 - 3e-16 59.4 16.3 9.3e-15 54.5 0.1 2.3 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 KZN88170.1 - 3.7e-09 36.0 0.3 0.027 13.3 0.0 3.3 3 0 0 3 3 3 3 Vacuolar protein sorting 38 APG6 PF04111.12 KZN88170.1 - 0.016 15.2 0.0 0.048 13.6 0.0 1.7 2 0 0 2 2 2 0 Apg6 BARA domain Mhr1 PF12829.7 KZN88171.1 - 3.3e-28 97.6 0.3 6.8e-28 96.6 0.3 1.6 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination DUF1843 PF08898.10 KZN88171.1 - 1.6 9.3 6.7 0.68 10.5 3.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) PP2C PF00481.21 KZN88172.1 - 5.1e-62 209.8 1.9 3.5e-50 171.0 0.1 3.3 2 1 1 3 3 3 2 Protein phosphatase 2C Trp_syntA PF00290.20 KZN88173.1 - 6.7e-94 313.5 0.0 9.9e-94 313.0 0.0 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 KZN88173.1 - 2.6e-48 164.9 0.3 4.4e-48 164.2 0.3 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PPO1_KFDV PF12143.8 KZN88174.1 - 0.043 13.9 0.2 0.056 13.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF_B2219) Kdo PF06293.14 KZN88175.1 - 9.2e-05 21.9 0.1 0.00021 20.7 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KZN88175.1 - 0.0033 17.4 4.5 0.007 16.3 0.1 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF3886 PF13025.6 KZN88175.1 - 0.014 15.5 12.8 0.014 15.5 12.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) Pkinase PF00069.25 KZN88175.1 - 0.074 12.4 0.0 0.2 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein kinase domain RIO1 PF01163.22 KZN88175.1 - 0.15 11.6 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Helo_like_N PF17111.5 KZN88176.1 - 7.4e-21 74.5 2.4 2.2e-19 69.7 2.4 2.4 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins F-box-like PF12937.7 KZN88176.1 - 0.00017 21.4 0.1 0.00045 20.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN88176.1 - 0.00028 20.7 0.1 0.006 16.4 0.0 2.4 2 0 0 2 2 2 1 F-box domain Sigma70_r4_2 PF08281.12 KZN88180.1 - 3.2e-05 23.5 0.0 3.8 7.3 0.0 3.9 4 0 0 4 4 4 3 Sigma-70, region 4 MarR_2 PF12802.7 KZN88180.1 - 0.00019 21.2 1.4 15 5.5 0.0 4.1 1 1 3 4 4 4 3 MarR family HTH_5 PF01022.20 KZN88180.1 - 0.0039 17.0 0.3 53 3.8 0.0 4.2 5 0 0 5 5 5 0 Bacterial regulatory protein, arsR family HTH_AsnC-type PF13404.6 KZN88180.1 - 0.0093 15.8 0.0 57 3.7 0.0 3.6 4 0 0 4 4 4 0 AsnC-type helix-turn-helix domain Fe_dep_repress PF01325.19 KZN88180.1 - 0.011 15.9 0.5 56 4.0 0.0 3.8 4 0 0 4 4 4 0 Iron dependent repressor, N-terminal DNA binding domain HTH_Tnp_ISL3 PF13542.6 KZN88180.1 - 0.056 12.9 0.1 72 2.9 0.0 4.1 5 0 0 5 5 5 0 Helix-turn-helix domain of transposase family ISL3 HTH_IclR PF09339.10 KZN88180.1 - 0.075 12.8 0.2 51 3.8 0.0 3.5 4 0 0 4 4 4 0 IclR helix-turn-helix domain HTH_22 PF13309.6 KZN88180.1 - 0.17 12.0 0.0 93 3.2 0.0 3.5 4 0 0 4 4 4 0 HTH domain DUF3328 PF11807.8 KZN88181.1 - 2.1e-35 122.5 0.0 2.6e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Ank_4 PF13637.6 KZN88182.1 - 6.6e-85 278.5 15.1 3.6e-07 30.6 0.0 21.0 14 4 6 20 20 20 17 Ankyrin repeats (many copies) Ank_2 PF12796.7 KZN88182.1 - 2.6e-84 277.9 9.9 2.3e-14 53.8 0.2 13.9 6 5 6 14 14 14 12 Ankyrin repeats (3 copies) Ank PF00023.30 KZN88182.1 - 6e-59 194.1 35.9 5.3e-06 26.7 0.3 22.1 23 0 0 23 23 23 11 Ankyrin repeat Ank_3 PF13606.6 KZN88182.1 - 8.6e-59 188.6 18.2 1.1e-05 25.4 0.0 21.1 21 1 1 22 22 22 11 Ankyrin repeat Ank_5 PF13857.6 KZN88182.1 - 1.7e-57 190.7 16.2 1.4e-05 25.2 0.0 16.8 16 2 1 17 17 17 10 Ankyrin repeats (many copies) NACHT PF05729.12 KZN88182.1 - 1.9e-08 34.4 0.0 5.8e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KZN88182.1 - 8.1e-06 26.3 0.1 4.5e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain ResIII PF04851.15 KZN88182.1 - 0.013 15.6 0.0 0.038 14.0 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KZN88182.1 - 0.06 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KZN88182.1 - 0.077 13.3 0.0 4.3 7.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain adh_short PF00106.25 KZN88183.1 - 1.9e-10 40.5 0.0 8e-05 22.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KZN88183.1 - 6e-10 39.1 0.0 0.00012 21.8 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KZN88183.1 - 0.066 12.7 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ketoacyl-synt PF00109.26 KZN88184.1 - 1.1e-67 228.2 0.0 3.1e-67 226.8 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KZN88184.1 - 4.3e-58 196.2 0.1 1e-57 195.0 0.1 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KZN88184.1 - 7.7e-56 189.5 0.1 1.4e-55 188.7 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KZN88184.1 - 3.4e-51 174.7 0.1 6e-51 173.8 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KZN88184.1 - 1.1e-37 128.7 0.2 3e-37 127.2 0.2 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KZN88184.1 - 5e-21 75.3 0.0 1.6e-20 73.6 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 KZN88184.1 - 1.7e-16 61.5 0.0 3.1e-14 54.1 0.0 3.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 KZN88184.1 - 4.7e-16 59.3 0.0 1.2e-15 58.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN88184.1 - 1.1e-12 48.1 0.0 2.7e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KZN88184.1 - 2.1e-12 47.2 0.1 2e-11 44.0 0.0 2.7 3 0 0 3 3 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 KZN88184.1 - 2.3e-12 46.8 0.1 6.8e-12 45.3 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_25 PF13649.6 KZN88184.1 - 1.4e-11 44.9 0.0 5.7e-11 43.0 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN88184.1 - 3e-08 34.2 0.1 2.2e-07 31.4 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain adh_short_C2 PF13561.6 KZN88184.1 - 7.6e-08 32.2 0.2 2.1e-07 30.8 0.0 1.8 2 0 0 2 2 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_31 PF13847.6 KZN88184.1 - 8.5e-08 32.1 0.0 2.6e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KZN88184.1 - 1.9e-05 24.2 0.0 3.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.25 KZN88184.1 - 4.2e-05 23.8 0.1 0.00012 22.3 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 KZN88184.1 - 0.0022 17.9 0.3 0.0062 16.4 0.3 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_16 PF10294.9 KZN88184.1 - 0.0051 16.6 0.0 0.014 15.2 0.0 1.6 1 1 0 1 1 1 1 Lysine methyltransferase Thiolase_N PF00108.23 KZN88184.1 - 0.0061 16.0 0.2 0.013 14.8 0.2 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_24 PF13578.6 KZN88184.1 - 0.15 13.1 0.1 4.4 8.4 0.0 3.1 2 0 0 2 2 2 0 Methyltransferase domain Zn_clus PF00172.18 KZN88185.1 - 3.6e-09 36.6 10.7 6.6e-09 35.8 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.10 KZN88185.1 - 0.016 15.5 7.7 0.048 14.0 7.7 1.8 1 0 0 1 1 1 0 Opy2 protein adh_short PF00106.25 KZN88186.1 - 1.3e-20 73.7 0.0 1e-16 61.0 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KZN88186.1 - 6.3e-12 45.5 0.0 6.3e-11 42.3 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN88186.1 - 0.00017 21.6 0.0 0.0003 20.7 0.0 1.4 1 0 0 1 1 1 1 KR domain GMC_oxred_N PF00732.19 KZN88187.1 - 4.5e-54 183.8 0.0 5.9e-54 183.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KZN88187.1 - 3.1e-31 108.8 0.0 5.7e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KZN88187.1 - 3.1e-06 27.0 0.1 0.054 13.1 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KZN88187.1 - 0.00076 18.7 0.1 0.61 9.1 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KZN88187.1 - 0.0096 16.1 0.2 0.026 14.8 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KZN88187.1 - 0.044 12.8 0.1 0.065 12.3 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KZN88187.1 - 0.048 12.9 0.2 0.17 11.1 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PS-DH PF14765.6 KZN88189.1 - 3.7e-76 256.2 0.0 5.8e-76 255.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 KZN88189.1 - 1.5e-70 237.6 0.0 3.1e-70 236.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KZN88189.1 - 5.4e-59 199.1 0.0 1.2e-58 197.9 0.0 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KZN88189.1 - 1.8e-54 185.4 0.0 3.3e-54 184.6 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KZN88189.1 - 2.6e-29 101.6 0.1 6.7e-29 100.3 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KZN88189.1 - 3.4e-21 75.8 0.0 7.9e-21 74.6 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KZN88189.1 - 3.9e-09 36.2 0.0 1.9e-08 34.0 0.0 2.2 3 0 0 3 3 3 1 short chain dehydrogenase ADH_N PF08240.12 KZN88189.1 - 5.7e-05 23.0 0.0 0.00016 21.5 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 KZN88189.1 - 8.1e-05 22.1 0.4 0.00021 20.8 0.4 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_zinc_N PF00107.26 KZN88189.1 - 0.0018 18.2 0.1 0.0053 16.7 0.1 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.25 KZN88189.1 - 0.0019 18.5 0.0 0.0051 17.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ACP_syn_III PF08545.10 KZN88189.1 - 0.0099 15.7 0.3 0.031 14.1 0.3 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Pyr_redox_3 PF13738.6 KZN88191.1 - 1.3e-17 64.0 0.0 1.7e-14 53.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KZN88191.1 - 3.1e-11 42.4 0.0 1.4e-07 30.3 0.0 2.4 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KZN88191.1 - 6.9e-09 35.3 0.1 2.3e-07 30.3 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KZN88191.1 - 2.8e-08 33.9 0.3 0.058 13.4 0.0 3.9 3 1 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KZN88191.1 - 1.1e-07 31.4 0.0 0.00024 20.4 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN88191.1 - 1.6e-06 28.2 0.0 4.6e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KZN88191.1 - 3.5e-06 26.8 0.1 1.9 8.0 0.0 3.4 3 1 0 3 3 3 3 FAD dependent oxidoreductase HI0933_like PF03486.14 KZN88191.1 - 0.0032 16.2 0.0 1.2 7.7 0.0 2.9 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.17 KZN88191.1 - 0.023 13.9 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Transferase PF02458.15 KZN88192.1 - 2.4e-09 36.3 0.0 8.5e-08 31.3 0.0 2.3 3 0 0 3 3 3 2 Transferase family adh_short_C2 PF13561.6 KZN88193.1 - 8.6e-51 172.7 2.0 1.8e-50 171.7 2.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN88193.1 - 2.3e-38 131.6 0.5 5.8e-38 130.3 0.5 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN88193.1 - 4.1e-06 26.8 0.7 8.5e-06 25.8 0.7 1.5 1 1 0 1 1 1 1 KR domain HHH_5 PF14520.6 KZN88193.1 - 0.057 14.0 0.3 0.12 13.0 0.3 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain FAD_binding_3 PF01494.19 KZN88194.1 - 1.5e-21 77.1 0.0 4e-21 75.7 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KZN88194.1 - 2.5e-07 30.1 0.0 4.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KZN88194.1 - 3.2e-06 26.6 0.0 3.3e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KZN88194.1 - 4.7e-06 26.1 0.2 0.0089 15.3 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN88194.1 - 1.3e-05 25.3 1.6 4.9e-05 23.5 0.3 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KZN88194.1 - 0.0002 20.6 0.5 0.00031 19.9 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KZN88194.1 - 0.00044 19.9 1.0 0.0067 16.1 0.8 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KZN88194.1 - 0.0014 18.0 0.3 0.14 11.5 0.0 2.7 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KZN88194.1 - 0.01 16.4 0.4 0.57 10.8 0.3 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KZN88194.1 - 0.023 14.0 0.0 0.047 12.9 0.0 1.5 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KZN88194.1 - 0.053 12.2 0.1 0.14 10.8 0.2 1.6 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 KZN88194.1 - 0.069 13.1 0.1 2.7 8.0 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF3237 PF11578.8 KZN88195.1 - 1.7e-13 50.6 0.0 2.1e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Pro_isomerase PF00160.21 KZN88196.1 - 6.7e-40 136.9 0.0 1.3e-39 136.0 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 KZN88196.1 - 0.00034 20.7 0.1 0.0023 18.1 0.0 2.3 1 1 0 2 2 2 1 U-box domain zf-NOSIP PF15906.5 KZN88196.1 - 0.00067 19.7 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 KZN88196.1 - 0.0014 18.1 0.1 0.013 14.9 0.1 2.4 1 1 0 1 1 1 1 Rtf2 RING-finger DUF1479 PF07350.12 KZN88197.1 - 5.2e-08 32.1 0.6 0.0019 17.0 0.0 3.9 3 1 0 3 3 3 2 Protein of unknown function (DUF1479) PhyH PF05721.13 KZN88197.1 - 4.3e-07 30.4 0.1 8.1e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans PF04082.18 KZN88197.1 - 0.02 13.9 4.0 0.17 10.9 4.0 2.2 1 1 0 1 1 1 0 Fungal specific transcription factor domain DUF3145 PF11343.8 KZN88198.1 - 0.053 13.1 0.1 0.11 12.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3145) SRR1 PF07985.12 KZN88198.1 - 0.12 12.5 0.1 0.36 10.9 0.1 1.8 1 0 0 1 1 1 0 SRR1 Methyltransf_PK PF05891.12 KZN88199.1 - 9.4e-72 241.1 0.0 1.1e-71 240.8 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KZN88199.1 - 0.00012 22.7 0.1 0.00029 21.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN88199.1 - 0.0027 17.6 0.0 0.0047 16.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN88199.1 - 0.0057 17.3 0.1 0.011 16.3 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain CitG PF01874.16 KZN88199.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase TPT PF03151.16 KZN88200.1 - 2.3e-25 89.6 23.8 2.7e-25 89.3 23.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KZN88200.1 - 6.3e-05 22.3 21.5 0.0013 18.0 21.5 2.3 1 1 0 1 1 1 1 UAA transporter family MFS_1 PF07690.16 KZN88201.1 - 4.5e-15 55.4 15.2 4.5e-15 55.4 15.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Ecm29 PF13001.7 KZN88201.1 - 0.11 11.1 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Proteasome stabiliser UPF0052 PF01933.18 KZN88202.1 - 3.4e-61 207.0 0.0 4.2e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 zf-C3HC4_3 PF13920.6 KZN88203.1 - 1.4e-09 37.7 11.3 3.5e-09 36.4 11.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KZN88203.1 - 1.7e-09 37.4 9.0 3.6e-09 36.4 9.0 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KZN88203.1 - 3.2e-07 30.3 5.4 3.2e-07 30.3 5.4 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KZN88203.1 - 1.5e-06 28.0 10.7 3e-06 27.1 10.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KZN88203.1 - 1.5e-06 27.9 13.0 3.4e-06 26.8 8.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KZN88203.1 - 4.7e-06 26.8 12.8 9.8e-06 25.8 12.8 1.6 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KZN88203.1 - 6.7e-05 23.0 9.5 0.00036 20.6 9.6 2.1 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KZN88203.1 - 0.00029 20.6 13.0 0.0065 16.3 13.2 2.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KZN88203.1 - 0.006 16.4 5.4 0.073 13.0 2.8 2.3 2 0 0 2 2 2 1 zf-RING of BARD1-type protein FANCL_C PF11793.8 KZN88203.1 - 0.019 15.1 8.0 0.053 13.7 8.0 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.8 KZN88203.1 - 0.023 14.5 5.5 0.062 13.1 5.5 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rad50_zn_hook PF04423.14 KZN88203.1 - 0.024 14.5 0.8 0.26 11.2 0.1 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-UDP PF14569.6 KZN88203.1 - 0.028 14.5 4.0 0.045 13.9 4.0 1.3 1 0 0 1 1 1 0 Zinc-binding RING-finger DNA_ligase_ZBD PF03119.16 KZN88203.1 - 0.14 12.2 4.2 0.21 11.6 0.4 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-RING_4 PF14570.6 KZN88203.1 - 0.23 11.3 8.8 0.91 9.4 8.8 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.11 KZN88203.1 - 0.24 11.4 5.6 0.5 10.3 5.6 1.5 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) DUF1644 PF07800.12 KZN88203.1 - 2 8.4 8.1 5.3 7.1 1.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1644) Auto_anti-p27 PF06677.12 KZN88203.1 - 2.3 8.5 9.7 1.6 9.0 0.3 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-rbx1 PF12678.7 KZN88203.1 - 6.6 7.1 12.9 24 5.3 12.9 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain DZR PF12773.7 KZN88203.1 - 10 6.3 11.2 3.2e+02 1.4 11.1 2.4 1 1 0 1 1 1 0 Double zinc ribbon DNApol_Exo PF18136.1 KZN88204.1 - 2.1e-105 351.9 0.0 3.4e-105 351.2 0.0 1.3 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KZN88204.1 - 5e-55 187.1 0.0 8e-55 186.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DUF1841 PF08897.11 KZN88204.1 - 0.091 12.8 0.1 0.23 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1841) DUF1454 PF07305.12 KZN88204.1 - 0.18 11.2 0.0 0.39 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) CorA PF01544.18 KZN88205.1 - 2e-23 83.2 8.6 1.7e-17 63.7 0.6 3.3 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein SQS_PSY PF00494.19 KZN88206.1 - 1.5e-54 185.2 0.0 1.9e-54 184.9 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase SNF2_N PF00176.23 KZN88207.1 - 6e-70 235.7 0.0 8.1e-70 235.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KZN88207.1 - 6e-23 80.6 0.0 1.3e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KZN88207.1 - 1.7e-12 47.7 0.0 4.3e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 KZN88207.1 - 0.00013 21.7 8.7 0.00023 21.0 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KZN88207.1 - 0.00058 19.6 7.1 0.0013 18.5 7.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KZN88207.1 - 0.0036 17.3 0.0 0.012 15.6 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 KZN88207.1 - 0.0042 17.4 10.9 0.011 16.0 10.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KZN88207.1 - 0.0049 16.9 9.9 0.011 15.7 9.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KZN88207.1 - 0.0081 16.0 11.4 0.017 15.0 11.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KZN88207.1 - 0.016 15.1 10.6 0.031 14.2 10.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KZN88207.1 - 1.7 8.9 10.7 3.4 7.9 10.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING GTP_EFTU PF00009.27 KZN88209.1 - 2.2e-18 66.5 0.0 5.7e-18 65.2 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KZN88209.1 - 1.2e-06 28.8 1.8 4.5e-06 26.9 1.8 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KZN88209.1 - 3.9e-05 23.9 0.0 9.3e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain PduV-EutP PF10662.9 KZN88209.1 - 0.011 15.4 0.4 1.3 8.7 0.1 3.1 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 KZN88209.1 - 0.043 13.9 0.1 0.11 12.6 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 KZN88209.1 - 0.34 10.9 1.1 0.98 9.5 0.6 2.0 2 0 0 2 2 2 0 Dynamin family LSM PF01423.22 KZN88210.1 - 4.1e-19 68.0 0.2 5.2e-19 67.7 0.2 1.2 1 0 0 1 1 1 1 LSM domain ATP13 PF12921.7 KZN88211.1 - 7.1e-25 87.1 0.0 1.9e-24 85.7 0.0 1.8 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_3 PF13812.6 KZN88211.1 - 1.4e-05 25.0 0.0 0.044 13.8 0.0 2.7 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 KZN88211.1 - 0.014 15.6 0.0 13 6.1 0.0 3.6 3 0 0 3 3 3 0 PPR repeat family PIG-L PF02585.17 KZN88212.1 - 6.4e-31 107.7 0.1 1.2e-30 106.8 0.1 1.5 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase LDB19 PF13002.7 KZN88213.1 - 3.1e-58 196.7 0.0 4.8e-58 196.1 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 KZN88213.1 - 4.9e-08 33.1 0.0 1.5e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain D-ser_dehydrat PF14031.6 KZN88214.1 - 5e-26 91.2 0.6 1.3e-25 89.8 0.2 2.0 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KZN88214.1 - 2.8e-13 50.0 0.0 4.4e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain CcmD PF04995.14 KZN88215.1 - 0.27 11.4 3.3 0.43 10.7 3.3 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) FtsJ PF01728.19 KZN88216.1 - 1.1e-08 35.3 0.0 1.9e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 KZN88216.1 - 0.15 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AAA PF00004.29 KZN88217.1 - 1.6e-11 44.8 0.0 8.4e-11 42.4 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KZN88217.1 - 1.2e-09 38.8 0.1 1.8e-08 35.0 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KZN88217.1 - 1.8e-08 34.8 0.0 4e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Cdc6_C PF09079.11 KZN88217.1 - 1e-07 31.8 0.0 3.7e-07 30.0 0.0 1.9 1 1 0 1 1 1 1 CDC6, C terminal winged helix domain KTI12 PF08433.10 KZN88217.1 - 3.8e-05 23.3 0.3 0.17 11.3 0.2 2.3 2 0 0 2 2 2 2 Chromatin associated protein KTI12 AAA_lid_10 PF17872.1 KZN88217.1 - 5.8e-05 23.2 0.1 0.00019 21.5 0.0 1.9 2 0 0 2 2 2 1 AAA lid domain AAA_7 PF12775.7 KZN88217.1 - 0.0014 18.2 0.0 0.0033 17.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region Rad17 PF03215.15 KZN88217.1 - 0.0031 17.5 0.0 0.012 15.6 0.0 2.0 1 1 0 1 1 1 1 Rad17 P-loop domain NTPase_1 PF03266.15 KZN88217.1 - 0.0034 17.3 0.0 0.0064 16.4 0.0 1.5 1 0 0 1 1 1 1 NTPase PIF1 PF05970.14 KZN88217.1 - 0.009 15.2 0.0 0.022 13.9 0.0 1.6 2 0 0 2 2 2 1 PIF1-like helicase TIP49 PF06068.13 KZN88217.1 - 0.013 14.7 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase_2 PF01637.18 KZN88217.1 - 0.016 15.1 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KZN88217.1 - 0.027 14.8 0.0 0.059 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TniB PF05621.11 KZN88217.1 - 0.051 13.0 0.0 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein DUF815 PF05673.13 KZN88217.1 - 0.068 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.12 KZN88217.1 - 0.096 12.6 0.1 0.25 11.2 0.1 1.7 1 1 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KZN88217.1 - 0.17 12.4 0.6 1.1 9.8 0.0 2.5 3 0 0 3 3 3 0 ABC transporter Thioredoxin_7 PF13899.6 KZN88218.1 - 2.2e-17 63.0 0.0 4.5e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 KZN88218.1 - 2e-13 49.9 0.0 4e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KZN88218.1 - 1.3e-08 34.9 0.0 7.9e-08 32.4 0.0 2.1 2 0 0 2 2 2 1 UBX domain Thioredoxin_2 PF13098.6 KZN88218.1 - 0.017 15.5 0.0 0.036 14.5 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredox_DsbH PF03190.15 KZN88218.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Pkinase PF00069.25 KZN88219.1 - 1.2e-68 231.3 0.0 1.7e-68 230.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN88219.1 - 2.5e-49 167.9 0.0 5.5e-49 166.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KZN88219.1 - 1.4e-05 24.6 0.0 0.00036 20.0 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KZN88219.1 - 0.00012 21.0 0.0 0.00022 20.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Fungal_trans PF04082.18 KZN88220.1 - 2.1e-24 86.0 0.3 3.2e-24 85.4 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN88220.1 - 6.1e-07 29.5 10.5 1e-06 28.7 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MR_MLE_C PF13378.6 KZN88221.1 - 4.8e-41 140.7 0.0 6.1e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KZN88221.1 - 2.6e-10 40.5 0.0 4.4e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain adh_short_C2 PF13561.6 KZN88222.1 - 3.1e-31 108.8 0.0 3.3e-31 108.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN88222.1 - 1.3e-14 54.1 0.0 1.5e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Amidohydro_2 PF04909.14 KZN88223.1 - 1.5e-16 61.0 1.1 2.8e-16 60.2 0.2 1.7 2 0 0 2 2 2 1 Amidohydrolase RhoGAP PF00620.27 KZN88224.1 - 7.2e-15 55.1 0.3 1.9e-14 53.7 0.1 1.8 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.21 KZN88224.1 - 5.4e-10 39.2 0.0 1.1e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 KZN88224.1 - 3.4e-07 30.4 0.0 1e-06 28.9 0.0 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Phage_TAC_8 PF10666.9 KZN88224.1 - 0.031 14.6 0.7 0.2 11.9 0.2 2.4 2 0 0 2 2 2 0 Phage tail assembly chaperone protein Gp14 ()A118 DUF4823 PF16105.5 KZN88224.1 - 0.073 12.9 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4823) AA_permease PF00324.21 KZN88225.1 - 4.7e-149 497.0 38.3 5.4e-149 496.8 38.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KZN88225.1 - 8.2e-39 133.6 37.0 1e-38 133.3 37.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 KZN88225.1 - 0.029 13.2 0.6 0.059 12.2 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) LSM PF01423.22 KZN88226.1 - 4e-20 71.3 0.1 4.4e-20 71.1 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KZN88226.1 - 0.11 12.7 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain DNA_pol_A_exo1 PF01612.20 KZN88227.1 - 1.5e-17 63.8 0.0 2.5e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease Pex2_Pex12 PF04757.14 KZN88228.1 - 2.2e-46 158.3 5.5 3e-46 157.8 5.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 KZN88228.1 - 3.9e-12 45.8 9.5 6.4e-12 45.1 9.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KZN88228.1 - 5.7e-10 38.9 7.4 8.8e-10 38.3 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KZN88228.1 - 7.6e-10 38.5 6.6 1.2e-09 37.9 6.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KZN88228.1 - 8.6e-10 38.8 10.3 1.3e-09 38.2 10.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KZN88228.1 - 3.6e-08 33.3 3.3 3.6e-08 33.3 3.3 1.7 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KZN88228.1 - 5.6e-07 29.3 6.6 9.3e-07 28.6 6.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KZN88228.1 - 1.3e-06 28.2 6.7 2.1e-06 27.6 6.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KZN88228.1 - 1.5e-05 25.1 8.6 2.7e-05 24.2 8.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KZN88228.1 - 4e-05 23.8 8.7 8.5e-05 22.8 8.7 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KZN88228.1 - 0.0015 18.6 6.3 0.0026 17.8 6.3 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 KZN88228.1 - 0.041 13.8 2.5 0.074 12.9 2.5 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 KZN88228.1 - 0.053 13.6 3.4 0.091 12.8 2.9 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.15 KZN88228.1 - 0.08 13.1 0.0 0.38 11.0 0.0 2.0 2 0 0 2 2 2 0 U-box domain zf-RING_4 PF14570.6 KZN88228.1 - 0.15 11.9 7.4 0.32 10.8 7.4 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.21 KZN88228.1 - 4.3 7.6 7.6 11 6.4 7.6 1.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain EXS PF03124.14 KZN88229.1 - 2.1e-99 333.0 16.3 2.4e-99 332.8 16.3 1.0 1 0 0 1 1 1 1 EXS family CMAS PF02353.20 KZN88230.1 - 9.2e-62 208.8 0.0 1.2e-61 208.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KZN88230.1 - 7.1e-10 39.5 0.0 1.4e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN88230.1 - 2e-09 37.5 0.0 3.3e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN88230.1 - 5.2e-09 36.6 0.0 1e-08 35.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN88230.1 - 5.6e-05 23.8 0.0 0.00011 22.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KZN88230.1 - 0.0061 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.14 KZN88230.1 - 0.0085 15.6 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KZN88230.1 - 0.029 14.5 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase MetW PF07021.12 KZN88230.1 - 0.038 13.6 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PCMT PF01135.19 KZN88230.1 - 0.066 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Tropomyosin_1 PF12718.7 KZN88232.1 - 7.5e-49 165.6 36.2 8.8e-49 165.3 36.2 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 KZN88232.1 - 3.7e-09 36.3 35.9 0.00017 21.1 14.4 2.8 1 1 1 2 2 2 2 Tropomyosin Uso1_p115_C PF04871.13 KZN88232.1 - 0.0013 19.1 38.0 0.012 15.9 15.1 2.0 1 1 1 2 2 2 2 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-F_leu_zip PF10473.9 KZN88232.1 - 0.0024 17.9 5.6 0.0024 17.9 5.6 2.9 1 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KASH_CCD PF14662.6 KZN88232.1 - 0.0082 16.0 33.1 0.0095 15.8 22.5 2.2 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH CASP_C PF08172.12 KZN88232.1 - 0.011 15.1 18.7 0.23 10.8 0.9 2.1 2 0 0 2 2 2 0 CASP C terminal KLRAQ PF10205.9 KZN88232.1 - 0.013 15.7 23.8 0.026 14.7 9.7 2.8 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein GAS PF13851.6 KZN88232.1 - 0.029 13.7 32.5 0.42 9.9 22.9 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 KZN88232.1 - 0.03 14.5 34.4 0.44 10.7 13.7 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KZN88232.1 - 0.053 12.4 34.4 0.24 10.2 12.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Laminin_II PF06009.12 KZN88232.1 - 0.094 12.7 20.7 0.24 11.4 8.3 2.1 1 1 1 2 2 2 0 Laminin Domain II ADIP PF11559.8 KZN88232.1 - 0.1 12.7 32.8 4.6 7.3 14.3 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.6 KZN88232.1 - 0.14 12.6 34.0 0.32 11.4 16.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF3450 PF11932.8 KZN88232.1 - 0.22 10.8 29.5 0.08 12.2 5.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) bZIP_1 PF00170.21 KZN88232.1 - 0.26 11.4 30.8 1.6 8.9 0.3 4.4 2 1 2 4 4 4 0 bZIP transcription factor DUF4407 PF14362.6 KZN88232.1 - 0.27 10.5 22.9 0.43 9.9 22.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 KZN88232.1 - 0.39 11.1 29.0 3.5 8.0 17.5 2.0 1 1 1 2 2 2 0 Fez1 UPF0242 PF06785.11 KZN88232.1 - 0.44 10.6 34.2 1.8 8.7 14.6 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DHR10 PF18595.1 KZN88232.1 - 0.45 10.6 37.0 2 8.5 13.5 2.7 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain MPS2 PF17060.5 KZN88232.1 - 0.48 9.6 18.2 0.86 8.8 18.2 1.4 1 1 0 1 1 1 0 Monopolar spindle protein 2 DUF724 PF05266.14 KZN88232.1 - 0.56 10.0 27.3 0.46 10.3 9.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Fmp27_WPPW PF10359.9 KZN88232.1 - 0.78 8.5 27.2 0.14 11.0 11.6 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain APG6_N PF17675.1 KZN88232.1 - 0.91 10.0 41.1 2.6 8.6 26.9 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF1664 PF07889.12 KZN88232.1 - 0.97 9.5 16.5 3.4 7.7 5.7 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Jnk-SapK_ap_N PF09744.9 KZN88232.1 - 1.2 9.4 33.9 1.2 9.4 23.1 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 TANGO2 PF05742.12 KZN88232.1 - 1.2 9.1 6.9 1.4 8.9 6.3 1.4 1 1 0 1 1 1 0 Transport and Golgi organisation 2 BRE1 PF08647.11 KZN88232.1 - 1.3 9.2 32.5 8 6.6 9.1 3.1 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase ZapB PF06005.12 KZN88232.1 - 1.4 9.4 39.6 0.75 10.3 1.8 3.8 1 1 1 2 2 1 0 Cell division protein ZapB SlyX PF04102.12 KZN88232.1 - 1.4 9.6 26.1 1.9 9.2 2.2 3.9 1 1 3 4 4 4 0 SlyX TMF_TATA_bd PF12325.8 KZN88232.1 - 1.4 9.1 28.9 3.9 7.7 18.3 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Lebercilin PF15619.6 KZN88232.1 - 1.5 8.5 35.0 1.5 8.5 16.0 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease MAD PF05557.13 KZN88232.1 - 2 6.7 32.1 1 7.6 20.7 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein bZIP_2 PF07716.15 KZN88232.1 - 2.3 8.4 36.1 1.5 9.0 2.6 5.1 2 2 3 5 5 5 0 Basic region leucine zipper NABP PF07990.12 KZN88232.1 - 2.3 7.6 7.8 2.5 7.6 7.8 1.2 1 0 0 1 1 1 0 Nucleic acid binding protein NABP DUF812 PF05667.11 KZN88232.1 - 2.4 6.9 31.2 3.3 6.5 31.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FlaC_arch PF05377.11 KZN88232.1 - 2.6 8.5 20.6 2.4 8.6 0.6 4.3 1 1 2 4 4 4 0 Flagella accessory protein C (FlaC) Atg14 PF10186.9 KZN88232.1 - 3.3 6.7 26.0 1.4 7.9 10.9 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cep57_CLD_2 PF14197.6 KZN88232.1 - 3.3 7.9 35.0 2.7 8.2 3.1 4.2 1 1 3 4 4 4 0 Centrosome localisation domain of PPC89 Nup54 PF13874.6 KZN88232.1 - 3.6 7.7 27.2 0.79 9.8 8.5 3.1 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 TPR_MLP1_2 PF07926.12 KZN88232.1 - 4.3 7.4 39.0 1.7 8.7 13.2 2.9 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF16 PF01519.16 KZN88232.1 - 6 7.4 23.1 6.5 7.3 5.2 2.7 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF5320 PF17253.2 KZN88232.1 - 6.6 7.9 22.4 3.9 8.6 4.8 3.3 3 1 0 3 3 3 0 Family of unknown function (DUF5320) DUF2203 PF09969.9 KZN88232.1 - 7.2 7.3 21.5 1.8e+04 -5.2 21.5 2.3 1 1 0 1 1 0 0 Uncharacterized conserved protein (DUF2203) YabA PF06156.13 KZN88232.1 - 7.9 7.2 26.2 23 5.7 0.4 2.9 1 1 1 2 2 1 0 Initiation control protein YabA VGPC1_C PF16799.5 KZN88232.1 - 9.2 6.3 14.3 0.45 10.5 3.2 3.2 2 1 1 3 3 3 0 C-terminal membrane-localisation domain of ion-channel, VCN1 Nop25 PF09805.9 KZN88233.1 - 1.6e-38 132.2 19.4 1.6e-38 132.2 19.4 2.8 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) ATP-synt_S1 PF05827.12 KZN88234.1 - 6.7e-05 22.7 0.1 0.00012 22.0 0.1 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) OAD_gamma PF04277.13 KZN88234.1 - 0.024 15.2 0.4 0.042 14.5 0.4 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Cu_amine_oxid PF01179.20 KZN88235.1 - 3.2e-163 543.4 1.9 3.9e-163 543.2 1.9 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KZN88235.1 - 0.0031 17.7 0.0 0.0061 16.8 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 KZN88235.1 - 0.0086 16.5 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Fungal_trans_2 PF11951.8 KZN88236.1 - 2.9e-51 174.5 0.4 7e-51 173.2 0.4 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KZN88237.1 - 1.3e-35 123.0 34.0 1.4e-35 122.9 33.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KZN88237.1 - 0.0022 17.4 7.3 0.0022 17.4 7.3 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Pex24p PF06398.11 KZN88238.1 - 5.4e-100 334.9 0.2 7.7e-100 334.4 0.2 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Pam16 PF03656.13 KZN88239.1 - 1e-31 109.6 0.3 1.2e-31 109.3 0.3 1.0 1 0 0 1 1 1 1 Pam16 Closter_coat PF01785.17 KZN88239.1 - 0.01 15.1 0.0 0.023 14.0 0.0 1.5 2 0 0 2 2 2 0 Closterovirus coat protein Aldo_ket_red PF00248.21 KZN88240.1 - 6.5e-65 219.2 0.0 8.5e-65 218.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family NTP_transf_2 PF01909.23 KZN88241.1 - 1.6e-10 41.1 0.0 4.1e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 KZN88241.1 - 1.1e-09 38.3 0.9 4.9e-09 36.3 0.5 2.3 2 0 0 2 2 2 1 Cid1 family poly A polymerase Polbeta PF18765.1 KZN88241.1 - 0.041 14.0 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Bravo_FIGEY PF13882.6 KZN88241.1 - 0.51 11.7 0.0 0.51 11.7 0.0 2.4 3 0 0 3 3 3 0 Bravo-like intracellular region PRKCSH-like PF12999.7 KZN88243.1 - 2.6e-43 147.8 15.9 8.9e-27 94.0 1.4 3.4 4 0 0 4 4 4 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KZN88243.1 - 3.7e-33 114.4 8.0 1.2e-32 112.7 3.7 2.8 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KZN88243.1 - 3.2e-07 31.3 1.6 1e-06 29.6 1.6 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 KZN88243.1 - 0.00043 20.2 2.0 0.0011 18.9 2.0 1.6 1 0 0 1 1 1 1 Autophagy-related protein 27 MRP-S25 PF13741.6 KZN88243.1 - 0.0012 18.5 0.6 0.0024 17.5 0.6 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 PRCC PF10253.9 KZN88243.1 - 0.016 16.0 1.0 0.038 14.8 0.1 2.0 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting GTP-bdg_M PF16360.5 KZN88243.1 - 0.11 13.0 4.4 0.3 11.7 3.1 2.4 2 1 1 3 3 3 0 GTP-binding GTPase Middle Region Gb3_synth PF04572.12 KZN88243.1 - 0.14 12.4 0.1 11 6.3 0.1 2.5 2 0 0 2 2 2 0 Alpha 1,4-glycosyltransferase conserved region DUF4407 PF14362.6 KZN88243.1 - 0.28 10.5 16.9 0.95 8.8 13.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 KZN88243.1 - 0.46 10.7 0.1 0.46 10.7 0.1 3.3 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Lectin_N PF03954.14 KZN88243.1 - 2.2 8.0 4.2 1.6 8.5 0.1 2.5 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Ldl_recept_a PF00057.18 KZN88243.1 - 7.5 6.9 14.7 0.65 10.3 1.9 3.1 3 0 0 3 3 3 0 Low-density lipoprotein receptor domain class A Rtf2 PF04641.12 KZN88244.1 - 2.8e-65 220.3 1.1 3.9e-65 219.8 1.1 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 KZN88244.1 - 1.3e-09 37.8 0.4 0.0015 18.3 0.0 3.0 2 1 1 3 3 3 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KZN88244.1 - 0.00025 21.0 1.2 0.0036 17.3 0.3 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KZN88244.1 - 0.0019 18.1 0.1 0.0046 16.9 0.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KZN88244.1 - 0.051 13.4 1.1 1.3 9.0 0.2 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-NOSIP PF15906.5 KZN88244.1 - 0.065 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_3 PF13920.6 KZN88244.1 - 0.072 13.0 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KZN88244.1 - 0.14 12.5 0.7 0.27 11.6 0.1 1.9 2 0 0 2 2 2 0 Ring finger domain Plasmodium_Vir PF05795.11 KZN88244.1 - 0.77 9.1 3.8 1.2 8.5 3.8 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Ribosomal_L50 PF10501.9 KZN88245.1 - 1.2e-18 67.2 0.1 2e-18 66.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal subunit 39S ArsA_ATPase PF02374.15 KZN88245.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase Thiolase_N PF00108.23 KZN88246.1 - 1.1e-73 247.8 0.2 1.5e-73 247.4 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KZN88246.1 - 5e-44 148.9 0.8 1.4e-43 147.5 0.8 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KZN88246.1 - 0.01 15.5 0.3 0.057 13.0 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Polysacc_deac_2 PF04748.13 KZN88246.1 - 0.043 13.0 0.0 0.077 12.2 0.0 1.4 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase RNase_H PF00075.24 KZN88247.1 - 4.5e-12 46.4 0.0 8.6e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KZN88247.1 - 0.13 12.1 0.0 18 5.2 0.0 2.6 2 0 0 2 2 2 0 Reverse transcriptase-like DAHP_synth_1 PF00793.20 KZN88249.1 - 5.7e-99 330.4 0.0 7.1e-99 330.1 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family COX14 PF14880.6 KZN88250.1 - 1.4e-18 66.4 0.4 1.4e-18 66.4 0.4 1.9 3 0 0 3 3 3 1 Cytochrome oxidase c assembly ECM11 PF15463.6 KZN88250.1 - 0.015 15.9 2.0 0.021 15.4 0.0 2.1 2 1 0 2 2 2 0 Extracellular mutant protein 11 DUF2458 PF10454.9 KZN88251.1 - 1.5e-64 216.8 0.2 1.9e-64 216.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) Fungal_trans PF04082.18 KZN88252.1 - 6.8e-13 48.3 0.2 1.2e-12 47.4 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain CDO_I PF05995.12 KZN88253.1 - 1.9e-39 134.7 0.0 2.4e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 KZN88253.1 - 0.0053 16.2 0.0 0.0071 15.8 0.0 1.3 1 1 0 1 1 1 1 PCO_ADO TFIID_30kDa PF03540.13 KZN88253.1 - 0.085 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit NAD_binding_1 PF00175.21 KZN88254.1 - 4.3e-27 94.9 0.0 6.8e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KZN88254.1 - 8.9e-16 58.1 0.0 1.5e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KZN88254.1 - 1.1e-06 28.8 0.0 0.0015 18.7 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain APH PF01636.23 KZN88255.1 - 5e-15 56.1 0.0 2.5e-14 53.8 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Arylsulfotran_2 PF14269.6 KZN88256.1 - 1.6e-42 145.9 0.9 2.5e-42 145.3 0.9 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KZN88256.1 - 9.6e-12 44.5 0.3 2.2e-10 40.0 0.3 2.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Hexokinase_2 PF03727.16 KZN88259.1 - 5.4e-58 196.2 0.0 7.5e-58 195.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KZN88259.1 - 8.1e-46 156.4 0.0 1.2e-45 155.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase ketoacyl-synt PF00109.26 KZN88260.1 - 2.3e-69 233.8 0.0 5.6e-69 232.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KZN88260.1 - 4.3e-63 212.5 0.0 1.3e-62 210.9 0.0 1.9 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KZN88260.1 - 2.1e-56 191.8 0.1 3.7e-56 191.0 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KZN88260.1 - 1.2e-47 162.6 0.0 2e-47 161.9 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KZN88260.1 - 5.3e-38 129.7 0.3 2.6e-37 127.4 0.1 2.4 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 KZN88260.1 - 4.4e-17 62.2 0.1 2.6e-16 59.7 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 KZN88260.1 - 6.9e-17 62.8 0.0 2e-16 61.3 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 KZN88260.1 - 3e-16 59.9 0.0 8.6e-16 58.4 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 KZN88260.1 - 1.2e-14 54.4 0.0 9e-14 51.6 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 KZN88260.1 - 3.5e-12 46.4 0.0 9.9e-12 44.9 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 KZN88260.1 - 1.1e-06 28.5 0.1 2.4e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 KZN88260.1 - 3.3e-06 27.4 0.9 8.1e-06 26.1 0.9 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KZN88260.1 - 0.0038 16.6 0.0 0.0096 15.3 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain SAT PF16073.5 KZN88260.1 - 0.0049 16.6 0.7 0.021 14.5 0.7 1.9 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ACP_syn_III PF08545.10 KZN88260.1 - 0.015 15.1 0.0 0.044 13.6 0.0 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III YjeF_N PF03853.15 KZN88260.1 - 0.065 13.1 0.1 18 5.2 0.0 2.9 2 0 0 2 2 2 0 YjeF-related protein N-terminus FSH1 PF03959.13 KZN88261.1 - 1.5e-18 67.2 0.0 4.8e-18 65.6 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Insulin_TMD PF17870.1 KZN88262.1 - 0.075 13.1 0.6 0.13 12.3 0.6 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment ADK PF00406.22 KZN88263.1 - 1.2e-42 145.6 0.0 1.5e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KZN88263.1 - 8.9e-33 113.6 0.0 1.2e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KZN88263.1 - 6.3e-08 33.2 0.0 9e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KZN88263.1 - 2.8e-07 30.8 0.0 6.8e-06 26.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KZN88263.1 - 3.1e-06 27.0 0.0 0.071 12.8 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase Ploopntkinase3 PF18751.1 KZN88263.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 PCI PF01399.27 KZN88264.1 - 4.2e-11 43.3 0.0 8.7e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 PCI domain eIF3m_C_helix PF18005.1 KZN88264.1 - 7.1e-11 41.6 3.5 1.9e-10 40.2 3.5 1.8 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix Adeno_PV PF03910.13 KZN88265.1 - 2.8 6.5 6.7 3.6 6.2 6.7 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV 4HBT PF03061.22 KZN88266.1 - 2.8e-07 30.8 0.1 4.7e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KZN88267.1 - 1.6e-53 182.5 0.3 1.8e-53 182.3 0.3 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily RTA1 PF04479.13 KZN88268.1 - 2.7e-54 183.9 13.4 2.7e-54 183.9 13.4 1.5 1 1 1 2 2 2 1 RTA1 like protein DUF4491 PF14898.6 KZN88268.1 - 5.5 7.5 12.9 4.1 7.9 0.5 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4491) Glyco_transf_20 PF00982.21 KZN88269.1 - 1.2e-159 532.1 0.0 1.8e-159 531.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KZN88269.1 - 1.9e-36 125.4 0.1 3e-36 124.7 0.1 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Stk19 PF10494.9 KZN88270.1 - 5.4e-90 301.4 0.0 6.8e-90 301.0 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 PTR PF12789.7 KZN88270.1 - 0.12 12.5 0.0 0.55 10.3 0.0 2.0 1 1 1 2 2 2 0 Phage tail repeat like DUF3074 PF11274.8 KZN88271.1 - 5.5e-36 124.3 0.0 7e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) zf-H2C2_2 PF13465.6 KZN88274.1 - 1.4e-11 44.3 15.9 3.8e-06 27.1 1.3 4.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KZN88274.1 - 3.4e-10 39.8 20.2 0.00088 19.6 4.7 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KZN88274.1 - 5.1e-06 26.3 15.0 0.0056 16.7 0.0 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KZN88274.1 - 0.0015 19.2 31.4 0.021 15.6 3.7 4.5 4 0 0 4 4 3 3 C2H2-type zinc finger zf-Di19 PF05605.12 KZN88274.1 - 0.0042 17.3 8.8 0.011 16.0 5.3 2.6 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 KZN88274.1 - 0.0092 16.1 7.2 0.014 15.5 1.9 2.5 2 0 0 2 2 2 1 Zinc ribbon domain Rad50_zn_hook PF04423.14 KZN88274.1 - 0.01 15.7 2.0 0.23 11.3 0.3 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C2H2_9 PF16293.5 KZN88274.1 - 0.016 15.1 1.7 3 7.8 0.2 3.4 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2HC_2 PF13913.6 KZN88274.1 - 0.041 13.8 0.9 0.041 13.8 0.9 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2HE PF16278.5 KZN88274.1 - 0.077 13.5 14.0 0.17 12.3 1.3 3.1 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger DZR PF12773.7 KZN88274.1 - 0.11 12.5 6.9 1.4 9.0 6.8 2.2 1 1 1 2 2 2 0 Double zinc ribbon HypA PF01155.19 KZN88274.1 - 0.15 12.1 2.5 0.4 10.7 2.5 1.6 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_9 PF14369.6 KZN88274.1 - 0.44 10.8 3.9 28 5.1 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon zf-CHCC PF10276.9 KZN88274.1 - 0.5 10.5 5.7 5.5 7.1 0.2 2.9 3 0 0 3 3 3 0 Zinc-finger domain zinc-ribbons_6 PF07191.12 KZN88274.1 - 1.4 8.9 5.0 5.5 7.1 5.0 1.9 1 1 0 1 1 1 0 zinc-ribbons zf-C2H2_jaz PF12171.8 KZN88274.1 - 1.5 9.2 12.7 0.4 11.0 1.2 3.8 5 0 0 5 5 4 0 Zinc-finger double-stranded RNA-binding zf-FPG_IleRS PF06827.14 KZN88274.1 - 1.9 8.5 6.4 2.1 8.3 0.6 2.7 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-ISL3 PF14690.6 KZN88274.1 - 2.4 8.9 8.8 11 6.8 0.3 3.2 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_ribbon_SprT PF17283.2 KZN88274.1 - 2.6 8.1 11.4 9.1 6.3 0.5 2.5 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-C2H2_3rep PF18868.1 KZN88274.1 - 9.1 7.0 8.8 10 6.8 2.8 3.4 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats FixQ PF05545.11 KZN88275.1 - 0.028 14.4 6.6 0.95 9.5 0.3 3.1 2 1 1 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ DUF1218 PF06749.12 KZN88275.1 - 0.029 14.9 0.6 0.029 14.9 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) MARVEL PF01284.23 KZN88275.1 - 0.28 11.2 14.8 0.054 13.5 8.2 2.2 1 1 0 2 2 2 0 Membrane-associating domain Cnd2 PF05786.14 KZN88276.1 - 0 1044.1 4.2 0 1043.9 4.2 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 KZN88276.1 - 0.0083 16.3 0.9 0.033 14.4 0.0 2.3 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Na_Ca_ex PF01699.24 KZN88277.1 - 1.8e-53 180.6 38.0 1.1e-28 100.1 16.7 3.0 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Fungal_trans PF04082.18 KZN88278.1 - 4.6e-13 48.8 0.1 1.1e-12 47.6 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN88278.1 - 3.7e-07 30.2 11.9 6.4e-07 29.4 9.1 2.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 KZN88279.1 - 1.6e-23 83.5 0.1 2.5e-22 79.6 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KZN88279.1 - 1.8e-05 24.9 0.1 4.3e-05 23.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KZN88279.1 - 0.00016 21.4 1.0 0.00038 20.1 0.7 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KZN88279.1 - 0.0025 18.3 0.1 0.007 16.9 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KZN88279.1 - 0.011 15.0 0.1 0.024 13.9 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KZN88279.1 - 0.022 14.8 0.3 0.093 12.7 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding SE PF08491.10 KZN88279.1 - 0.034 13.2 0.0 0.86 8.6 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Amino_oxidase PF01593.24 KZN88279.1 - 0.055 12.7 0.2 7.1 5.8 0.0 2.5 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 KZN88279.1 - 0.074 11.9 0.6 0.86 8.4 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase DUF4388 PF14332.6 KZN88279.1 - 0.1 12.9 0.0 1.1 9.6 0.0 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4388) Lycopene_cycl PF05834.12 KZN88279.1 - 0.12 11.4 1.1 10 5.0 0.1 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein ketoacyl-synt PF00109.26 KZN88280.1 - 2.2e-69 233.8 0.0 4.9e-69 232.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KZN88280.1 - 5.2e-33 113.6 0.0 9.8e-33 112.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain HTH_51 PF18558.1 KZN88280.1 - 3.2e-29 100.6 0.0 7.1e-29 99.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain NAD_binding_4 PF07993.12 KZN88280.1 - 4e-24 85.2 0.0 6.8e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.21 KZN88280.1 - 7e-24 84.9 0.0 1.2e-23 84.1 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Methyltransf_12 PF08242.12 KZN88280.1 - 1.4e-15 57.8 0.0 4.4e-15 56.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain SAT PF16073.5 KZN88280.1 - 2.7e-13 50.2 6.5 1.9e-10 40.9 0.2 3.5 3 1 1 4 4 4 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_23 PF13489.6 KZN88280.1 - 4.1e-12 46.3 0.0 1.2e-11 44.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN88280.1 - 2.7e-09 37.6 0.0 1.2e-08 35.5 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KZN88280.1 - 4.7e-09 36.5 1.4 1e-08 35.4 0.3 2.3 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.12 KZN88280.1 - 2.3e-08 34.5 0.0 8.3e-08 32.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN88280.1 - 4.7e-08 33.0 0.0 1.3e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KZN88280.1 - 5.4e-05 22.8 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KAsynt_C_assoc PF16197.5 KZN88280.1 - 0.00041 20.8 0.0 0.0013 19.2 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension NodS PF05401.11 KZN88280.1 - 0.0007 19.3 0.0 0.0033 17.1 0.0 2.1 2 0 0 2 2 2 1 Nodulation protein S (NodS) Thiolase_N PF00108.23 KZN88280.1 - 0.037 13.4 0.1 0.074 12.4 0.1 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain Methyltransf_33 PF10017.9 KZN88280.1 - 0.059 12.5 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent KR PF08659.10 KZN88280.1 - 0.14 12.0 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 KR domain ketoacyl-synt PF00109.26 KZN88281.1 - 5.9e-71 239.0 0.2 1.4e-70 237.8 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KZN88281.1 - 1.1e-57 195.5 0.0 1.9e-57 194.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KZN88281.1 - 2e-57 194.0 0.2 7.2e-57 192.2 0.1 2.1 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 KZN88281.1 - 6.7e-40 137.5 1.6 2.8e-39 135.5 1.5 2.0 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KZN88281.1 - 1.1e-39 135.0 0.6 6.8e-39 132.5 0.2 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KZN88281.1 - 2.9e-15 56.7 0.1 8.3e-15 55.2 0.1 1.8 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 KZN88281.1 - 2.7e-14 54.4 0.0 1.5e-13 51.9 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KZN88281.1 - 8.7e-14 51.6 1.2 7.6e-13 48.6 0.0 2.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase adh_short PF00106.25 KZN88281.1 - 2e-11 43.7 0.0 5.7e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_12 PF08242.12 KZN88281.1 - 7.1e-10 39.5 0.0 1.7e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN88281.1 - 8.2e-08 32.2 0.0 1.7e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 KZN88281.1 - 2.5e-07 30.3 0.3 6e-07 29.1 0.3 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_25 PF13649.6 KZN88281.1 - 1e-06 29.3 0.0 3.6e-06 27.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN88281.1 - 6.4e-06 26.0 0.0 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KZN88281.1 - 0.00089 19.6 0.4 0.0022 18.3 0.4 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.12 KZN88281.1 - 0.0014 19.2 0.0 0.0048 17.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain YjeF_N PF03853.15 KZN88281.1 - 0.0058 16.5 0.8 0.55 10.1 0.0 3.2 3 0 0 3 3 3 1 YjeF-related protein N-terminus PALP PF00291.25 KZN88281.1 - 0.0067 15.9 2.2 0.01 15.3 0.3 2.3 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Fungal_trans PF04082.18 KZN88282.1 - 7.6e-15 54.6 0.3 1.6e-14 53.6 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3629 PF12302.8 KZN88282.1 - 0.043 13.2 0.2 0.13 11.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3629) TFR_dimer PF04253.15 KZN88282.1 - 0.14 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain MFS_1 PF07690.16 KZN88283.1 - 2.7e-31 108.8 31.9 2.7e-31 108.8 31.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2798 PF11391.8 KZN88283.1 - 0.027 14.5 1.3 0.027 14.5 1.3 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2798) TMEM40 PF15817.5 KZN88283.1 - 0.83 9.4 6.4 0.1 12.4 1.6 1.9 2 0 0 2 2 2 0 Transmembrane protein 40 family FAD_binding_4 PF01565.23 KZN88284.1 - 4.3e-25 88.1 1.3 8.2e-25 87.2 1.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KZN88284.1 - 2.8e-12 46.5 0.0 1.1e-11 44.6 0.0 2.1 1 0 0 1 1 1 1 Berberine and berberine like ALO PF04030.14 KZN88284.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase EF-hand_4 PF12763.7 KZN88285.1 - 8.4e-27 93.2 0.0 2e-14 53.4 0.0 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.20 KZN88285.1 - 1e-09 37.9 1.6 2.1e-09 36.9 1.6 1.6 1 0 0 1 1 1 1 WH2 motif DUF1720 PF08226.11 KZN88285.1 - 1.3e-08 35.1 85.5 2.8e-06 27.6 43.2 7.7 6 1 1 7 7 7 4 Domain of unknown function (DUF1720) EF-hand_7 PF13499.6 KZN88285.1 - 9.8e-05 22.7 2.0 0.038 14.4 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KZN88285.1 - 0.0029 17.0 0.0 1.5 8.5 0.0 2.7 2 0 0 2 2 2 2 EF hand RNA_pol_L_2 PF13656.6 KZN88286.1 - 1.1e-24 86.0 0.0 1.6e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KZN88286.1 - 4.1e-09 35.7 0.0 7.4e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain PBP1_TM PF14812.6 KZN88287.1 - 4.1 7.8 14.6 13 6.2 7.5 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleo_P87 PF07267.11 KZN88287.1 - 4.5 6.0 13.1 0.51 9.1 5.9 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 DUF1764 PF08576.10 KZN88287.1 - 6.2 7.8 10.4 0.72 10.8 3.7 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) PMT PF02366.18 KZN88288.1 - 5.7e-86 288.1 17.1 9.4e-86 287.4 17.1 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KZN88288.1 - 4.4e-67 225.6 1.4 4.4e-67 225.6 1.4 2.9 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KZN88288.1 - 2.8e-21 76.2 0.2 4.6e-21 75.5 0.2 1.3 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 KZN88288.1 - 0.0042 17.3 5.2 0.0042 17.3 5.2 4.0 4 1 1 5 5 5 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Erf4 PF10256.9 KZN88289.1 - 0.12 12.5 0.0 0.64 10.1 0.0 2.1 2 1 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family RNA_pol_3_Rpc31 PF11705.8 KZN88290.1 - 0.0039 17.5 1.7 0.0081 16.4 1.7 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 MFS_1 PF07690.16 KZN88291.1 - 3.5e-30 105.1 33.3 3.5e-30 105.1 33.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KZN88291.1 - 0.6 9.9 7.2 0.63 9.8 0.0 2.4 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4668 PF15701.5 KZN88292.1 - 3.1 7.6 5.9 7.4 6.4 0.0 3.4 2 2 2 4 4 4 0 Domain of unknown function (DUF4668) TMEM119 PF15724.5 KZN88292.1 - 5.1 7.1 5.5 0.52 10.3 0.6 1.7 2 0 0 2 2 2 0 TMEM119 family WD40 PF00400.32 KZN88293.1 - 0.00073 20.3 9.5 0.54 11.2 0.0 5.2 6 1 0 6 6 6 3 WD domain, G-beta repeat ATP-synt_E PF05680.12 KZN88294.1 - 3.9e-25 88.0 0.6 4.3e-25 87.9 0.6 1.0 1 0 0 1 1 1 1 ATP synthase E chain FCH PF00611.23 KZN88294.1 - 0.003 17.8 1.7 0.006 16.8 1.7 1.4 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Adhesin_P1_N PF18652.1 KZN88294.1 - 0.019 15.0 3.8 0.028 14.4 3.8 1.5 1 1 0 1 1 1 0 Adhesin P1 N-terminal domain Chordopox_A13L PF05961.11 KZN88294.1 - 0.11 12.8 2.4 0.46 10.8 1.5 2.0 1 1 1 2 2 2 0 Chordopoxvirus A13L protein CSN8_PSD8_EIF3K PF10075.9 KZN88295.1 - 1.9e-30 105.8 0.1 2.6e-30 105.3 0.1 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family STT3 PF02516.14 KZN88296.1 - 3.6e-145 484.6 35.2 3.3e-140 468.2 33.4 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Coiled-coil_56 PF09813.9 KZN88297.1 - 1.9e-05 24.7 0.0 2e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.8 KZN88298.1 - 2.2e-70 236.8 0.2 8.5e-70 234.9 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) p450 PF00067.22 KZN88299.1 - 2.3e-69 234.3 0.0 2.8e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_1 PF00175.21 KZN88300.1 - 1.6e-32 112.4 0.0 2.7e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KZN88300.1 - 5.6e-28 97.2 0.0 1.2e-27 96.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 KZN88300.1 - 4.4e-21 74.8 0.1 4.4e-21 74.8 0.1 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KZN88300.1 - 3.4e-05 24.0 0.0 0.00063 19.9 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KZN88300.1 - 0.035 14.3 0.0 3.2 8.0 0.0 2.4 1 1 1 2 2 2 0 Siderophore-interacting FAD-binding domain Rick_17kDa_Anti PF05433.15 KZN88300.1 - 0.053 13.4 2.2 0.13 12.1 2.2 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain 3HCDH_N PF02737.18 KZN88301.1 - 1.2e-32 113.3 0.0 1.6e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KZN88301.1 - 9.7e-09 35.7 0.0 1.9e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.23 KZN88301.1 - 7e-05 22.9 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 KZN88301.1 - 0.00047 20.3 0.0 0.0063 16.7 0.0 2.3 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF5050 PF16472.5 KZN88301.1 - 0.053 12.8 0.0 5.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5050) SWIRM-assoc_1 PF16495.5 KZN88301.1 - 0.07 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 SWIRM-associated region 1 Ldl_recept_b PF00058.17 KZN88301.1 - 0.1 13.1 3.9 5.5 7.6 0.1 4.9 5 1 0 5 5 5 0 Low-density lipoprotein receptor repeat class B 2-Hacid_dh_C PF02826.19 KZN88301.1 - 0.18 11.1 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fungal_trans PF04082.18 KZN88302.1 - 1.9e-12 46.8 0.9 4e-12 45.7 0.9 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN88302.1 - 4.2e-08 33.2 10.0 1e-07 31.9 10.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KZN88303.1 - 9.9e-44 149.7 38.1 9.9e-44 149.7 38.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN88303.1 - 2.4e-12 46.5 2.0 2.4e-12 46.5 2.0 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 KZN88303.1 - 0.001 18.5 4.1 0.001 18.5 4.1 2.6 1 1 1 2 2 2 2 Uncharacterised MFS-type transporter YbfB Fungal_trans PF04082.18 KZN88304.1 - 5.5e-24 84.6 1.1 8.5e-24 84.0 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sds3 PF08598.11 KZN88305.1 - 2.4e-19 70.2 1.1 2.4e-19 70.2 1.1 1.8 2 0 0 2 2 2 1 Sds3-like SUIM_assoc PF16619.5 KZN88305.1 - 0.0024 17.9 11.4 0.007 16.4 11.4 1.8 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 RRM_1 PF00076.22 KZN88306.1 - 8.6e-05 22.3 0.0 0.086 12.7 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pyr_redox_2 PF07992.14 KZN88308.1 - 2.1e-07 30.5 0.0 4.1e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KZN88308.1 - 1e-06 28.8 0.0 1.5e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KZN88308.1 - 0.0052 16.1 0.0 2.8 7.1 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KZN88308.1 - 0.0081 15.3 0.0 0.11 11.7 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GPI-anchored PF10342.9 KZN88310.1 - 8.8e-22 77.7 0.9 8.8e-22 77.7 0.9 2.9 2 1 0 2 2 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 KZN88310.1 - 0.00026 20.8 2.2 0.00052 19.9 2.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) Big_3_4 PF13754.6 KZN88310.1 - 0.015 15.0 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function SOG2 PF10428.9 KZN88310.1 - 0.13 11.5 24.1 0.15 11.3 24.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein GREB1 PF15782.5 KZN88310.1 - 0.56 7.3 15.1 0.62 7.1 15.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SAPS PF04499.15 KZN88310.1 - 0.82 8.4 4.9 0.91 8.2 4.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF572 PF04502.13 KZN88310.1 - 1.2 8.7 11.0 1.5 8.4 11.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) RIFIN PF02009.16 KZN88310.1 - 1.3 8.8 6.8 1.6 8.6 6.8 1.2 1 0 0 1 1 1 0 Rifin Macoilin PF09726.9 KZN88310.1 - 1.5 7.3 17.8 2.3 6.7 17.8 1.3 1 0 0 1 1 1 0 Macoilin family PPP4R2 PF09184.11 KZN88310.1 - 2.3 7.7 13.5 2.9 7.4 13.5 1.1 1 0 0 1 1 1 0 PPP4R2 DUF1387 PF07139.11 KZN88310.1 - 3.4 7.3 13.5 4.2 7.0 13.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) SDA1 PF05285.12 KZN88310.1 - 5.3 6.4 10.1 6.8 6.0 10.1 1.1 1 0 0 1 1 1 0 SDA1 Utp14 PF04615.13 KZN88310.1 - 5.4 5.5 12.0 6.5 5.2 12.0 1.0 1 0 0 1 1 1 0 Utp14 protein NUFIP1 PF10453.9 KZN88311.1 - 2.1e-15 56.3 1.3 2.1e-15 56.3 1.3 3.6 3 1 1 4 4 4 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.24 KZN88311.1 - 1.1e-08 34.8 4.8 1.9e-08 34.0 4.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KZN88311.1 - 5.9e-06 26.2 7.0 9.6e-06 25.5 7.0 1.4 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 KZN88311.1 - 0.00022 21.9 0.1 0.00022 21.9 0.1 2.7 2 0 0 2 2 2 1 Torus domain zf-CCCH_4 PF18044.1 KZN88311.1 - 0.00024 20.8 3.6 0.00039 20.1 3.6 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger AF-4 PF05110.13 KZN88311.1 - 0.0027 15.9 10.5 0.0027 15.9 10.5 2.7 2 1 1 3 3 3 1 AF-4 proto-oncoprotein Exonuc_VII_L PF02601.15 KZN88311.1 - 0.043 13.4 9.4 0.066 12.8 9.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-CCCH_2 PF14608.6 KZN88311.1 - 0.16 12.5 4.4 0.31 11.6 4.4 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger LMBR1 PF04791.16 KZN88311.1 - 3.9 6.3 8.4 6 5.7 8.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein RNA_pol_Rbc25 PF08292.12 KZN88312.1 - 4.7e-36 123.9 1.7 1.6e-35 122.2 1.7 1.8 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KZN88312.1 - 5.3e-14 52.3 0.0 7.9e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KZN88312.1 - 0.12 12.7 0.0 0.26 11.7 0.0 1.5 2 0 0 2 2 2 0 S1 RNA binding domain Cys_Met_Meta_PP PF01053.20 KZN88313.1 - 1.9e-140 467.7 0.1 2.2e-140 467.6 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KZN88313.1 - 2.9e-09 36.6 0.1 4.1e-09 36.1 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KZN88313.1 - 1.8e-07 30.8 0.1 3.4e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KZN88313.1 - 1.8e-06 27.2 0.8 3e-06 26.4 0.3 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KZN88313.1 - 0.00027 20.3 0.1 0.00045 19.6 0.1 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Methyltransf_16 PF10294.9 KZN88314.1 - 0.0043 16.8 0.0 3.1 7.5 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase Filament PF00038.21 KZN88316.1 - 0.032 13.8 68.6 0.0094 15.6 57.3 2.7 1 1 1 2 2 2 0 Intermediate filament protein DUF3584 PF12128.8 KZN88316.1 - 0.16 9.4 71.3 0.49 7.8 10.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.12 KZN88316.1 - 8.1 6.5 84.8 3.4 7.7 29.4 4.1 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Cellulase PF00150.18 KZN88317.1 - 1.8e-15 57.2 2.3 2.4e-15 56.7 2.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KZN88317.1 - 0.00031 20.0 0.3 0.00063 19.0 0.3 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KZN88317.1 - 0.00042 19.8 1.2 0.037 13.4 0.1 2.5 3 0 0 3 3 3 2 Beta-galactosidase AP_endonuc_2 PF01261.24 KZN88317.1 - 0.031 13.7 0.0 0.31 10.4 0.0 2.1 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel DUF5603 PF18231.1 KZN88317.1 - 0.052 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5603) Glyco_hydro_10 PF00331.20 KZN88317.1 - 0.054 12.7 0.1 0.3 10.2 0.0 2.2 3 0 0 3 3 3 0 Glycosyl hydrolase family 10 Acyltransferase PF01553.21 KZN88319.1 - 3.1e-16 59.2 0.0 5.9e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Pantoate_ligase PF02569.15 KZN88320.1 - 4.3e-90 301.5 0.0 5.1e-90 301.3 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase ATP-sulfurylase PF01747.17 KZN88320.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 ATP-sulfurylase DEAD PF00270.29 KZN88321.1 - 5e-44 150.1 0.1 7.3e-44 149.6 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 KZN88321.1 - 6.2e-19 68.0 0.0 1.2e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 KZN88321.1 - 6.9e-19 68.2 0.0 2.3e-18 66.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KZN88321.1 - 3.4e-06 27.2 0.3 1.6e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit FAM176 PF14851.6 KZN88321.1 - 0.002 17.8 1.7 0.039 13.6 0.4 2.9 2 0 0 2 2 2 1 FAM176 family ERCC3_RAD25_C PF16203.5 KZN88321.1 - 0.031 13.5 1.0 0.083 12.1 0.0 2.0 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase RXT2_N PF08595.11 KZN88321.1 - 0.19 11.7 5.1 0.24 11.4 1.7 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 KZN88321.1 - 6.1 7.3 16.1 0.56 10.6 6.3 2.9 3 0 0 3 3 3 0 Centromere protein B dimerisation domain WD40 PF00400.32 KZN88322.1 - 3.9e-13 49.7 6.8 0.015 16.1 0.1 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN88322.1 - 0.0026 18.0 0.1 6.7 7.1 0.0 4.2 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ank_5 PF13857.6 KZN88323.1 - 1e-15 57.5 1.7 2.8e-09 37.1 0.4 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KZN88323.1 - 1.8e-13 50.9 0.0 3.5e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KZN88323.1 - 4.7e-10 39.5 0.1 2e-05 24.8 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KZN88323.1 - 1e-08 34.7 0.0 0.0055 17.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KZN88323.1 - 2e-07 31.4 0.1 1.2e-06 28.9 0.1 2.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) HMMR_N PF15905.5 KZN88323.1 - 0.091 12.2 3.8 0.19 11.2 3.8 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal PKcGMP_CC PF16808.5 KZN88323.1 - 7.8 6.4 10.9 0.3 11.0 2.5 2.8 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Fungal_trans_2 PF11951.8 KZN88324.1 - 9.4e-14 51.0 0.0 2.1e-10 40.0 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN88324.1 - 4.6e-05 23.5 10.9 8.3e-05 22.6 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KZN88325.1 - 3.6e-44 151.2 80.0 3.2e-39 134.8 51.0 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN88325.1 - 2.4e-09 36.6 18.4 2.4e-09 36.6 18.4 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KZN88325.1 - 1.6e-05 23.5 21.5 2.7e-05 22.8 21.5 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KZN88325.1 - 3.7e-05 22.5 5.3 3.7e-05 22.5 5.3 3.4 2 1 1 3 3 3 2 MFS/sugar transport protein GATase PF00117.28 KZN88326.1 - 1.3e-13 51.2 0.0 1.8e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 KZN88326.1 - 0.0046 16.6 0.0 0.0073 15.9 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 KZN88326.1 - 0.036 13.8 0.1 1.2 8.9 0.1 2.8 1 1 0 1 1 1 0 Peptidase C26 OTU PF02338.19 KZN88327.1 - 1.2e-09 38.8 0.1 2.3e-09 37.8 0.1 1.5 1 1 0 1 1 1 1 OTU-like cysteine protease CUE PF02845.16 KZN88327.1 - 0.0015 18.2 0.1 0.0036 17.0 0.0 1.7 2 0 0 2 2 2 1 CUE domain Peptidase_C65 PF10275.9 KZN88327.1 - 0.02 14.3 0.0 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Peptidase C65 Otubain DMA PF03474.14 KZN88327.1 - 0.025 14.2 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 DMRTA motif UBA_4 PF14555.6 KZN88327.1 - 0.07 13.0 0.0 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 UBA-like domain DUF1296 PF06972.11 KZN88327.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) MRI PF15325.6 KZN88327.1 - 4.6 8.4 7.1 3.3 8.9 1.0 2.7 1 1 1 2 2 2 0 Modulator of retrovirus infection DAO PF01266.24 KZN88328.1 - 9.6e-26 91.2 0.1 1.2e-25 90.9 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase MFS_1 PF07690.16 KZN88330.1 - 5.1e-39 134.2 37.8 4.5e-34 117.9 28.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KZN88330.1 - 9.5e-06 24.4 23.6 6.4e-05 21.7 4.6 3.3 2 2 1 3 3 3 2 MFS/sugar transport protein MFS_4 PF06779.14 KZN88330.1 - 0.0062 15.9 7.6 0.0062 15.9 7.6 3.6 2 2 2 4 4 4 4 Uncharacterised MFS-type transporter YbfB COPI_assoc PF08507.10 KZN88331.1 - 5.7e-32 110.5 5.7 6.1e-32 110.4 5.7 1.0 1 0 0 1 1 1 1 COPI associated protein Cytochrom_B558a PF05038.13 KZN88331.1 - 0.089 12.3 1.7 0.15 11.6 1.7 1.3 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Cg6151-P PF10233.9 KZN88331.1 - 0.48 10.8 6.9 1.2 9.4 6.6 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein CG6151-P DUF2892 PF11127.8 KZN88331.1 - 5.3 7.1 15.1 2.2 8.4 4.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2892) GATA PF00320.27 KZN88332.1 - 4.3e-28 96.6 17.5 2.3e-14 52.7 6.1 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KZN88332.1 - 1.2e-05 24.7 2.7 0.0062 16.0 0.1 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 KZN88332.1 - 5.3e-05 23.1 3.2 0.078 12.9 0.5 2.5 2 0 0 2 2 2 2 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.10 KZN88332.1 - 0.00011 22.2 2.5 0.1 12.7 0.2 2.9 2 0 0 2 2 2 2 Zinc ribbon domain Auto_anti-p27 PF06677.12 KZN88332.1 - 0.0015 18.6 6.4 0.024 14.8 0.5 2.5 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 KZN88332.1 - 0.012 15.5 4.1 1.8 8.5 0.3 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 ArfGap PF01412.18 KZN88332.1 - 0.065 13.3 3.9 0.51 10.4 0.1 2.4 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf DZR PF12773.7 KZN88332.1 - 0.081 13.0 12.8 1.1 9.3 0.5 3.0 2 1 0 2 2 2 0 Double zinc ribbon Ribosomal_S27e PF01667.17 KZN88332.1 - 0.096 12.4 1.4 3.3 7.5 0.2 2.5 2 0 0 2 2 2 0 Ribosomal protein S27 CCDC-167 PF15188.6 KZN88332.1 - 0.19 12.1 1.1 0.34 11.3 1.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Nudix_N_2 PF14803.6 KZN88332.1 - 9 6.3 11.7 10 6.1 2.7 3.5 2 1 1 3 3 3 0 Nudix N-terminal PGA_cap PF09587.10 KZN88333.1 - 4.3e-60 203.3 0.0 5.7e-60 202.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap ABC2_membrane PF01061.24 KZN88334.1 - 2.2e-83 278.8 38.0 3.7e-46 157.2 15.9 2.6 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KZN88334.1 - 1.9e-40 138.6 0.0 1e-18 68.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KZN88334.1 - 8.6e-27 92.9 0.2 2e-23 82.1 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 KZN88334.1 - 2.3e-13 50.0 26.9 2.9e-08 33.2 8.6 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 KZN88334.1 - 1.4e-11 44.8 1.1 5.9e-11 42.8 0.1 2.6 3 0 0 3 3 2 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 KZN88334.1 - 3.4e-05 23.8 0.8 0.0052 16.7 0.2 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KZN88334.1 - 9e-05 22.9 0.2 0.074 13.4 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KZN88334.1 - 0.00013 21.9 0.0 0.17 11.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KZN88334.1 - 0.00046 19.9 0.4 0.082 12.7 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 KZN88334.1 - 0.00091 19.4 0.0 1.2 9.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KZN88334.1 - 0.00094 19.7 0.0 2.4 8.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KZN88334.1 - 0.0011 18.5 0.1 0.041 13.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KZN88334.1 - 0.0013 19.0 2.2 1.1 9.5 0.3 3.7 2 2 1 3 3 3 1 AAA domain cobW PF02492.19 KZN88334.1 - 0.0028 17.3 0.9 1.7 8.2 0.4 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KZN88334.1 - 0.0044 17.3 0.4 0.91 9.8 0.3 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KZN88334.1 - 0.031 14.3 0.2 7.9 6.6 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.19 KZN88334.1 - 0.061 12.7 0.0 0.43 10.0 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain NACHT PF05729.12 KZN88334.1 - 0.087 12.7 0.4 3.8 7.4 0.2 2.4 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 KZN88334.1 - 0.11 12.2 0.2 5.5 6.6 0.3 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KZN88334.1 - 0.12 11.6 0.3 4.4 6.5 0.2 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.6 KZN88334.1 - 0.13 12.6 0.2 13 6.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.9 KZN88334.1 - 0.21 11.3 0.5 8.9 6.1 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation bZIP_1 PF00170.21 KZN88335.1 - 1.5e-05 25.0 1.4 4.2e-05 23.5 1.4 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KZN88335.1 - 0.02 15.0 1.6 0.038 14.1 1.6 1.4 1 0 0 1 1 1 0 Basic region leucine zipper CinA PF02464.17 KZN88335.1 - 0.065 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Competence-damaged protein Tropomyosin_1 PF12718.7 KZN88335.1 - 0.073 13.2 0.5 0.13 12.4 0.5 1.4 1 0 0 1 1 1 0 Tropomyosin like Glutaredoxin2_C PF04399.13 KZN88335.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain adh_short PF00106.25 KZN88336.1 - 1.9e-37 128.6 0.0 3.2e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN88336.1 - 1.1e-26 93.9 0.0 1.5e-26 93.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KZN88336.1 - 3e-06 26.8 0.0 6.8e-06 25.7 0.0 1.5 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) KR PF08659.10 KZN88336.1 - 0.00034 20.6 0.0 0.00059 19.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KZN88336.1 - 0.0093 15.5 0.0 0.018 14.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KZN88336.1 - 0.089 12.8 0.0 0.21 11.5 0.0 1.6 2 0 0 2 2 2 0 Zinc-binding dehydrogenase ApbA PF02558.16 KZN88336.1 - 0.091 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KZN88336.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Tautomerase_3 PF14832.6 KZN88337.1 - 8.3e-57 191.2 0.1 9.3e-57 191.1 0.1 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme MFS_1 PF07690.16 KZN88339.1 - 1.8e-25 89.7 51.8 1.8e-25 89.7 51.8 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily MtrF PF09472.10 KZN88339.1 - 0.44 10.0 2.8 1.4 8.3 0.0 2.9 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Nitroreductase PF00881.24 KZN88340.1 - 5.6e-12 46.0 0.0 7e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family p450 PF00067.22 KZN88343.1 - 1.2e-46 159.4 0.0 1.5e-46 159.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 KZN88344.1 - 1.8e-20 73.1 5.3 2.7e-20 72.5 2.9 2.4 3 0 0 3 3 3 1 FAD binding domain MFS_3 PF05977.13 KZN88344.1 - 0.091 11.1 0.0 0.14 10.5 0.0 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector MFS_1 PF07690.16 KZN88346.1 - 1.3e-34 119.8 34.2 4.2e-34 118.0 35.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2243 PF10002.9 KZN88346.1 - 0.0086 16.2 2.0 0.039 14.1 2.0 2.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2243) Holin_BhlA PF10960.8 KZN88346.1 - 0.11 12.5 0.0 0.35 10.9 0.0 1.8 1 0 0 1 1 1 0 BhlA holin family ESSS PF10183.9 KZN88346.1 - 0.15 12.3 0.3 0.68 10.2 0.2 2.2 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) FAD_binding_3 PF01494.19 KZN88348.1 - 8.4e-16 58.1 0.2 3.1e-14 53.0 0.2 2.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KZN88348.1 - 1.1e-06 28.8 0.1 2.9e-06 27.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KZN88348.1 - 3.4e-05 23.2 0.0 0.17 11.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KZN88348.1 - 0.00024 21.6 0.0 0.057 14.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KZN88348.1 - 0.00041 20.0 0.1 0.00093 18.9 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KZN88348.1 - 0.066 12.5 0.0 9.8 5.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KZN88348.1 - 0.081 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Zn_clus PF00172.18 KZN88349.1 - 1.9e-09 37.5 15.4 3.7e-09 36.5 15.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep3 PF16846.5 KZN88349.1 - 0.054 12.0 0.7 0.083 11.4 0.7 1.2 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B ArsA_ATPase PF02374.15 KZN88349.1 - 0.054 12.7 0.0 0.09 11.9 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase MFS_1 PF07690.16 KZN88350.1 - 8.5e-36 123.6 31.6 5.1e-35 121.0 33.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KZN88350.1 - 2.7e-05 23.7 6.1 2.7e-05 23.7 6.1 2.4 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB YcxB PF14317.6 KZN88350.1 - 0.02 14.6 0.0 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 YcxB-like protein DUF373 PF04123.13 KZN88350.1 - 0.66 9.4 0.0 0.66 9.4 0.0 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF373) BatA PF07584.11 KZN88350.1 - 1.3 9.4 3.9 15 6.0 0.0 3.6 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal OPT PF03169.15 KZN88351.1 - 7e-169 563.4 43.4 9.1e-169 563.0 43.4 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein YtpI PF14007.6 KZN88351.1 - 0.13 12.5 0.1 0.13 12.5 0.1 2.4 3 0 0 3 3 3 0 YtpI-like protein adh_short PF00106.25 KZN88354.1 - 1.3e-53 181.4 0.2 1.7e-53 181.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN88354.1 - 2.9e-35 121.9 0.2 3.9e-35 121.5 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN88354.1 - 6.1e-12 45.8 0.0 9.1e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KZN88354.1 - 0.0043 16.2 0.5 0.0094 15.1 0.5 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KZN88354.1 - 0.023 14.9 0.1 0.04 14.2 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain RsgA_GTPase PF03193.16 KZN88354.1 - 0.31 10.9 1.4 0.82 9.6 0.5 1.9 1 1 1 2 2 2 0 RsgA GTPase MIT PF04212.18 KZN88356.1 - 0.00029 20.9 0.4 0.00049 20.1 0.4 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 KZN88356.1 - 0.047 13.4 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 TPR repeat TPR_7 PF13176.6 KZN88356.1 - 0.088 12.9 0.1 0.31 11.2 0.1 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat Ras PF00071.22 KZN88357.1 - 5.8e-59 198.3 0.3 6.8e-59 198.1 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KZN88357.1 - 9.2e-20 71.1 0.0 1.4e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KZN88357.1 - 1.8e-08 34.0 0.0 2.1e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KZN88357.1 - 1.1e-06 28.3 0.1 9.1e-06 25.3 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KZN88357.1 - 9.3e-05 22.4 1.2 0.21 11.5 0.1 2.4 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KZN88357.1 - 0.00059 19.9 0.0 0.00089 19.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KZN88357.1 - 0.0011 18.5 0.0 0.0018 17.8 0.0 1.3 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 KZN88357.1 - 0.0013 18.7 0.0 0.0025 17.8 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain CbiA PF01656.23 KZN88357.1 - 0.15 12.1 0.7 0.91 9.6 0.7 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 KZN88357.1 - 0.16 11.4 0.1 0.9 8.9 0.0 1.9 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase IstB_IS21 PF01695.17 KZN88357.1 - 0.16 11.6 0.9 2.5 7.8 0.1 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein ATP_bind_1 PF03029.17 KZN88357.1 - 0.19 11.5 2.3 1.6 8.5 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Ser_hydrolase PF06821.13 KZN88357.1 - 0.22 11.3 0.0 0.3 10.9 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase MoCF_biosynth PF00994.24 KZN88358.1 - 6.5e-36 123.1 0.0 1.1e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain Cofilin_ADF PF00241.20 KZN88359.1 - 2.1e-22 79.2 0.0 2.6e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DZR PF12773.7 KZN88360.1 - 0.053 13.5 27.3 0.32 11.1 10.3 3.6 2 2 1 3 3 3 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 KZN88360.1 - 0.068 13.9 18.7 0.5 11.1 0.5 3.7 2 1 1 3 3 3 0 zinc-ribbon family HypA PF01155.19 KZN88360.1 - 7.7 6.6 25.6 4.4 7.3 4.5 3.3 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 2OG-FeII_Oxy PF03171.20 KZN88361.1 - 6.7e-13 49.0 0.0 1.6e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KZN88361.1 - 1.5e-11 45.1 0.0 2.5e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal UPF0086 PF01868.16 KZN88362.1 - 1.4e-31 108.2 0.2 2.2e-31 107.6 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 tRNA_int_endo PF01974.17 KZN88363.1 - 2.6e-14 53.1 0.0 5.2e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain MTES_1575 PF18741.1 KZN88363.1 - 0.094 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 REase_MTES_1575 Totivirus_coat PF05518.11 KZN88363.1 - 0.67 7.9 4.3 0.83 7.6 4.3 1.0 1 0 0 1 1 1 0 Totivirus coat protein PAXNEB PF05625.11 KZN88365.1 - 1.9e-118 395.9 0.0 2.1e-118 395.7 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein RNA_pol_Rpb8 PF03870.15 KZN88366.1 - 1.1e-47 161.7 0.0 1.3e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 KZN88366.1 - 0.00012 22.2 0.0 0.014 15.4 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G DUF4743 PF15916.5 KZN88367.1 - 1.7e-13 50.6 0.0 2.4e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 KZN88367.1 - 1.6e-09 37.9 0.0 2.8e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Pox_E2-like PF04497.12 KZN88367.1 - 0.25 9.8 0.0 0.34 9.3 0.0 1.1 1 0 0 1 1 1 0 Poxviridae protein DUF775 PF05603.12 KZN88368.1 - 2.5e-63 213.2 0.0 2.8e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) MHYT PF03707.16 KZN88369.1 - 4.4e-23 81.2 16.8 1.7e-09 37.7 0.7 3.7 3 0 0 3 3 3 3 Bacterial signalling protein N terminal repeat Virul_fac_BrkB PF03631.15 KZN88369.1 - 0.63 9.6 7.7 0.26 10.9 3.0 2.1 1 1 0 2 2 2 0 Virulence factor BrkB ABC2_membrane_5 PF13346.6 KZN88369.1 - 5.1 6.6 7.3 0.52 9.8 2.6 1.7 1 1 1 2 2 2 0 ABC-2 family transporter protein Thioredoxin PF00085.20 KZN88370.1 - 3.7e-29 100.7 0.1 4e-29 100.6 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KZN88370.1 - 7e-07 29.7 0.0 9.8e-06 26.0 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KZN88370.1 - 2.4e-06 27.8 0.0 3.1e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 KZN88370.1 - 9.9e-06 25.5 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 KZN88370.1 - 2.1e-05 24.3 0.0 2.6e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 KZN88370.1 - 7.4e-05 22.9 0.0 9.7e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KZN88370.1 - 0.0037 17.0 0.1 0.0052 16.5 0.1 1.4 1 1 0 1 1 1 1 Redoxin Glutaredoxin PF00462.24 KZN88370.1 - 0.0053 17.0 0.0 0.0085 16.3 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin OST3_OST6 PF04756.13 KZN88370.1 - 0.02 14.3 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DSBA PF01323.20 KZN88370.1 - 0.059 13.1 0.0 1.2 8.8 0.0 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain PCYCGC PF13798.6 KZN88370.1 - 0.072 12.9 0.0 0.087 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif CW_7 PF08230.11 KZN88370.1 - 0.13 12.1 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 CW_7 repeat IF-2B PF01008.17 KZN88373.1 - 2.9e-49 167.8 0.0 3.5e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Nuf2 PF03800.14 KZN88374.1 - 6.1e-44 149.5 0.2 1.7e-43 148.1 0.2 1.8 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 KZN88374.1 - 4.9e-34 116.9 19.5 4.9e-34 116.9 19.5 3.8 3 1 0 3 3 3 1 Designed helical repeat protein 10 domain Bacillus_HBL PF05791.11 KZN88374.1 - 0.011 15.6 4.8 0.011 15.6 4.8 3.2 1 1 3 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) IFT46_B_C PF12317.8 KZN88374.1 - 3.1 7.5 10.0 1 9.1 5.8 2.3 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Adaptin_N PF01602.20 KZN88376.1 - 9.3e-98 328.0 0.0 2e-97 326.9 0.0 1.5 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KZN88376.1 - 2e-15 57.2 0.1 1.5e-13 51.1 0.0 3.4 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KZN88376.1 - 2e-09 37.7 0.0 0.00078 19.8 0.0 4.4 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.22 KZN88376.1 - 9.2e-08 31.7 1.2 0.086 13.1 0.0 5.3 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 KZN88376.1 - 0.00012 22.5 1.1 3.9 8.1 0.0 5.1 5 0 0 5 5 5 1 HEAT-like repeat TFIIA PF03153.13 KZN88376.1 - 0.00022 21.4 8.0 0.00044 20.4 8.0 1.5 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Cohesin_HEAT PF12765.7 KZN88376.1 - 0.0006 20.1 0.3 0.018 15.3 0.0 3.1 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion MID_MedPIWI PF18296.1 KZN88376.1 - 0.082 12.7 2.8 4.1 7.1 0.8 2.8 3 0 0 3 3 3 0 MID domain of medPIWI Sec16 PF12932.7 KZN88376.1 - 0.81 10.3 5.2 2.2 8.9 1.6 2.6 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region DUF913 PF06025.12 KZN88376.1 - 5.5 5.9 12.3 26 3.6 0.1 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) Astro_capsid_p PF12226.8 KZN88376.1 - 6.5 5.8 29.3 0.058 12.5 14.8 2.8 3 0 0 3 3 3 0 Turkey astrovirus capsid protein Amidohydro_1 PF01979.20 KZN88377.1 - 2.3e-44 152.1 0.2 2.9e-44 151.8 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KZN88377.1 - 8.8e-22 78.2 0.4 4.9e-15 56.0 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family Metallophos PF00149.28 KZN88378.1 - 9.1e-36 124.3 0.2 1.2e-35 123.9 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KZN88378.1 - 0.078 13.4 0.3 0.22 12.0 0.3 1.8 1 1 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 KZN88378.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Rho_GDI PF02115.17 KZN88379.1 - 8.9e-64 214.8 0.9 9.8e-64 214.7 0.9 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor KilA-N PF04383.13 KZN88380.1 - 0.00092 19.0 3.7 0.055 13.3 0.0 3.4 2 1 1 3 3 3 2 KilA-N domain CENP-H PF05837.12 KZN88380.1 - 3.4 8.1 18.6 0.93 9.9 4.8 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) FmiP_Thoc5 PF09766.9 KZN88380.1 - 3.4 6.9 21.1 2.1 7.5 8.0 2.2 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 GNAT_acetyltr_2 PF13718.6 KZN88380.1 - 4 6.8 8.5 6.6 6.1 0.3 2.2 2 0 0 2 2 2 0 GNAT acetyltransferase 2 DUF1682 PF07946.14 KZN88380.1 - 8.1 5.5 25.9 0.28 10.3 9.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) CLP1_N PF16573.5 KZN88381.1 - 2.8e-33 114.0 0.1 5.5e-33 113.1 0.1 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor CLP1_P PF16575.5 KZN88381.1 - 3e-30 105.4 0.0 1.6e-29 103.1 0.0 2.1 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 KZN88381.1 - 6.4e-24 84.6 0.0 2.1e-23 82.9 0.0 1.9 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.17 KZN88381.1 - 0.00027 20.8 0.0 0.0022 17.8 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KZN88381.1 - 0.0024 17.9 0.1 0.015 15.4 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_35 PF14516.6 KZN88381.1 - 0.016 14.1 0.0 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain AAA_24 PF13479.6 KZN88381.1 - 0.026 14.2 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KZN88381.1 - 0.029 14.0 0.0 8.4 6.0 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA PF00004.29 KZN88381.1 - 0.086 13.3 0.1 0.15 12.5 0.1 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 KZN88381.1 - 0.11 12.0 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B SRPRB PF09439.10 KZN88381.1 - 0.23 10.9 0.0 0.57 9.6 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gly_transf_sug PF04488.15 KZN88382.1 - 1.1e-14 54.8 0.0 2.1e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Acyl_transf_3 PF01757.22 KZN88383.1 - 1e-41 143.2 33.7 1.2e-41 142.9 33.7 1.1 1 0 0 1 1 1 1 Acyltransferase family CFEM PF05730.11 KZN88385.1 - 1.2e-14 54.2 9.5 1.7e-14 53.7 9.5 1.2 1 0 0 1 1 1 1 CFEM domain MGC-24 PF05283.11 KZN88385.1 - 0.0072 16.8 6.3 0.011 16.2 6.3 1.4 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin ADH_zinc_N PF00107.26 KZN88387.1 - 8.6e-27 93.7 0.0 1.3e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KZN88387.1 - 3.5e-21 76.7 0.0 5.4e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KZN88387.1 - 1.2e-09 38.1 0.0 1.7e-08 34.3 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain TIR_2 PF13676.6 KZN88387.1 - 0.15 12.7 0.0 0.27 11.8 0.0 1.4 1 0 0 1 1 1 0 TIR domain Arb1 PF09692.10 KZN88388.1 - 8.6e-116 387.4 0.9 3.8e-115 385.3 0.0 2.0 2 0 0 2 2 2 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 DUF4542 PF15075.6 KZN88388.1 - 0.071 13.5 0.7 0.19 12.1 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4542) IPK PF03770.16 KZN88389.1 - 8.8e-61 205.2 0.0 1.3e-60 204.7 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase CcdA PF07362.12 KZN88389.1 - 0.15 12.5 0.5 0.66 10.4 0.3 2.1 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA Ribosomal_S19 PF00203.21 KZN88390.1 - 9.9e-25 86.2 0.0 1.2e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 TFIID_30kDa PF03540.13 KZN88391.1 - 4.3e-22 77.8 0.1 6.5e-22 77.2 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.6 KZN88391.1 - 0.098 13.2 1.6 0.3 11.7 1.6 1.9 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 TRF PF08558.10 KZN88392.1 - 8.8e-89 297.2 0.4 1.3e-88 296.6 0.4 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 KZN88392.1 - 0.00066 19.8 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain His_Phos_2 PF00328.22 KZN88393.1 - 1.2e-07 31.5 0.0 4.7e-07 29.5 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.25 KZN88395.1 - 1.6e-74 250.6 0.0 2.2e-74 250.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN88395.1 - 2.7e-30 105.5 0.0 1.5e-21 76.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KZN88395.1 - 1.2e-08 34.7 0.0 0.028 13.7 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 KZN88395.1 - 0.0019 17.0 0.0 0.0036 16.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KZN88395.1 - 0.019 14.9 0.0 1.1 9.1 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KZN88395.1 - 0.08 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KZN88395.1 - 0.12 11.2 0.0 0.25 10.3 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain FA_desaturase PF00487.24 KZN88396.1 - 6.3e-27 95.0 29.0 9.7e-27 94.4 29.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KZN88396.1 - 8.1e-11 41.9 0.0 1.6e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DASH_Dad3 PF08656.10 KZN88397.1 - 6.6e-13 48.5 0.2 8.7e-13 48.2 0.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 Ribosomal_S5_C PF03719.15 KZN88398.1 - 4.8e-22 77.2 0.0 1e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KZN88398.1 - 6e-16 58.2 0.0 6e-16 58.2 0.0 2.2 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain tRNA_U5-meth_tr PF05958.11 KZN88399.1 - 1.6e-12 47.1 0.0 1.6e-05 24.1 0.0 2.5 3 0 0 3 3 3 2 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.20 KZN88399.1 - 7.9e-06 25.8 0.6 2.4e-05 24.2 0.1 2.0 2 0 0 2 2 2 1 TRAM domain Methyltransf_31 PF13847.6 KZN88399.1 - 0.0019 18.0 0.0 0.0081 16.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN88399.1 - 0.004 17.8 0.0 0.011 16.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KZN88399.1 - 0.056 12.8 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 KZN88399.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Actin PF00022.19 KZN88400.1 - 1.6e-88 297.1 0.0 4e-54 183.8 0.0 2.1 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 KZN88400.1 - 0.036 12.9 0.0 1 8.1 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Asparaginase_2 PF01112.18 KZN88401.1 - 4.8e-50 170.3 4.2 2.6e-29 102.2 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Tfb4 PF03850.14 KZN88402.1 - 8.5e-121 402.7 0.0 1e-120 402.4 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 UNC45-central PF11701.8 KZN88403.1 - 1.2e-43 148.7 1.9 5.9e-43 146.5 0.6 2.8 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central TPR_15 PF13429.6 KZN88403.1 - 0.058 12.6 0.2 0.11 11.7 0.2 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Arm PF00514.23 KZN88403.1 - 0.32 11.1 19.9 7.6 6.7 0.0 7.1 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat GDPD PF03009.17 KZN88404.1 - 1.2e-71 241.6 0.0 2.4e-71 240.5 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 KZN88404.1 - 7.3e-29 100.2 0.0 7.8e-09 36.0 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN88404.1 - 4.3e-24 84.6 3.3 1.2e-07 32.1 0.1 5.0 4 1 1 5 5 5 4 Ankyrin repeats (many copies) SPX PF03105.19 KZN88404.1 - 4.5e-23 82.8 10.5 6.3e-10 39.5 0.1 4.0 3 1 1 4 4 4 3 SPX domain Ank_3 PF13606.6 KZN88404.1 - 4.3e-19 66.6 0.1 0.0017 18.7 0.0 6.9 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 KZN88404.1 - 1.8e-16 59.8 0.8 0.049 14.1 0.0 5.9 5 1 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KZN88404.1 - 3.5e-15 55.9 0.1 8e-05 22.8 0.0 4.6 3 1 3 6 6 6 4 Ankyrin repeats (many copies) CHAD PF05235.14 KZN88404.1 - 0.53 10.2 4.5 0.27 11.2 1.1 2.0 2 0 0 2 2 2 0 CHAD domain F-box-like PF12937.7 KZN88405.1 - 1e-05 25.3 1.7 1e-05 25.3 1.7 2.2 2 0 0 2 2 2 1 F-box-like Polysacc_deac_1 PF01522.21 KZN88406.1 - 5.5e-17 61.8 0.0 8.5e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KZN88406.1 - 0.00023 20.9 0.0 0.00036 20.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 KZN88406.1 - 0.027 12.8 0.0 0.038 12.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) BRK PF07533.16 KZN88406.1 - 0.13 11.9 0.2 0.87 9.3 0.0 2.5 3 0 0 3 3 3 0 BRK domain Pyr_redox_2 PF07992.14 KZN88407.1 - 7.3e-39 133.7 0.0 9.3e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KZN88407.1 - 1.8e-15 57.2 0.1 2.1e-11 44.2 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KZN88407.1 - 6.6e-06 26.2 1.6 5.5 7.0 0.2 4.2 3 1 1 4 4 4 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KZN88407.1 - 2.3e-05 23.6 2.8 0.0045 16.1 0.0 3.4 4 0 0 4 4 4 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KZN88407.1 - 0.00028 20.2 1.1 0.0027 17.0 0.8 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KZN88407.1 - 0.00068 19.3 0.9 1.2 8.7 0.0 3.7 4 0 0 4 4 4 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KZN88407.1 - 0.0042 16.3 0.5 1.1 8.3 0.2 2.8 1 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KZN88407.1 - 0.0071 15.6 0.7 1.7 7.8 0.0 2.5 2 0 0 2 2 2 2 Thi4 family TrkA_N PF02254.18 KZN88407.1 - 0.065 13.5 0.4 14 6.0 0.1 3.6 3 1 0 3 3 3 0 TrkA-N domain Trp_halogenase PF04820.14 KZN88407.1 - 0.075 11.9 0.5 3.3 6.4 0.0 2.8 3 0 0 3 3 3 0 Tryptophan halogenase HNH_2 PF13391.6 KZN88408.1 - 2.4e-16 59.6 0.3 4e-16 58.9 0.3 1.4 1 0 0 1 1 1 1 HNH endonuclease Ank_2 PF12796.7 KZN88409.1 - 9.3e-69 228.0 15.4 6.8e-16 58.6 0.6 7.4 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN88409.1 - 2.1e-61 203.5 18.0 7.3e-11 42.4 0.0 9.3 6 3 4 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN88409.1 - 9.1e-52 167.0 13.3 0.0011 19.3 0.1 13.9 14 0 0 14 14 14 13 Ankyrin repeat Ank PF00023.30 KZN88409.1 - 5.2e-48 159.5 22.4 2.4e-05 24.5 0.1 13.6 13 0 0 13 13 13 10 Ankyrin repeat Ank_5 PF13857.6 KZN88409.1 - 1.1e-38 130.8 18.8 0.00012 22.3 0.3 11.3 3 2 9 12 12 12 11 Ankyrin repeats (many copies) Helo_like_N PF17111.5 KZN88409.1 - 0.0063 15.9 1.3 0.012 15.0 1.3 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Cu-oxidase_3 PF07732.15 KZN88410.1 - 2.8e-37 127.4 0.0 4.1e-36 123.6 0.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KZN88410.1 - 6.8e-30 103.6 0.7 1.3e-23 83.3 0.0 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KZN88410.1 - 1.4e-15 57.8 0.0 2.3e-14 53.8 0.0 2.7 2 1 0 2 2 2 1 Multicopper oxidase HeLo PF14479.6 KZN88411.1 - 6.1e-41 140.5 1.8 7.6e-41 140.2 1.8 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation GIDA_assoc PF13932.6 KZN88411.1 - 0.0095 16.1 1.6 0.023 14.9 1.4 1.7 1 1 0 1 1 1 1 GidA associated domain Fungal_trans_2 PF11951.8 KZN88412.1 - 9.3e-41 139.9 9.5 4.9e-22 78.3 3.7 2.0 1 1 1 2 2 2 2 Fungal specific transcription factor domain Arginase PF00491.21 KZN88413.1 - 1.1e-89 300.7 0.0 1.2e-89 300.5 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KZN88413.1 - 0.14 12.3 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 UPF0489 domain p450 PF00067.22 KZN88414.1 - 9e-57 192.8 0.0 3.6e-56 190.9 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 HRI1 PF16815.5 KZN88415.1 - 1.7e-24 86.8 0.0 3.6e-24 85.8 0.0 1.5 1 1 0 1 1 1 1 Protein HRI1 TauD PF02668.16 KZN88416.1 - 2.3e-47 162.0 0.4 2.9e-47 161.7 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family zf-C2H2 PF00096.26 KZN88417.1 - 5.4e-06 26.6 9.3 0.012 16.0 0.7 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type CXCL17 PF15211.6 KZN88417.1 - 0.047 14.4 4.5 0.088 13.6 4.5 1.4 1 0 0 1 1 1 0 VEGF co-regulated chemokine 1 zf-C2H2_4 PF13894.6 KZN88417.1 - 0.1 13.5 7.0 1.9 9.5 0.4 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger CHORD PF04968.12 KZN88417.1 - 1.2 9.9 5.9 23 5.8 4.1 2.7 2 1 1 3 3 3 0 CHORD zf-H2C2_2 PF13465.6 KZN88417.1 - 1.5 9.4 12.1 1.9 9.1 6.9 2.8 2 0 0 2 2 2 0 Zinc-finger double domain AA_permease_2 PF13520.6 KZN88418.1 - 3.8e-50 171.0 54.1 5e-50 170.6 54.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN88418.1 - 5.6e-22 78.0 45.4 9.1e-22 77.3 45.4 1.3 1 1 0 1 1 1 1 Amino acid permease Peptidase_S10 PF00450.22 KZN88421.1 - 2.6e-93 313.7 1.3 3.1e-93 313.4 1.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Lipase_3 PF01764.25 KZN88422.1 - 2.6e-35 121.3 0.0 4e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 KZN88422.1 - 3e-22 78.4 0.1 7.1e-22 77.2 0.1 1.7 1 0 0 1 1 1 1 Lipase 3 N-terminal region Hydrolase_4 PF12146.8 KZN88422.1 - 1.5e-06 27.7 0.0 2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KZN88422.1 - 5.2e-05 24.0 0.2 6.2e-05 23.7 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 KZN88422.1 - 0.00012 21.8 0.1 0.0002 21.0 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase Thioesterase PF00975.20 KZN88422.1 - 0.0006 20.0 0.0 0.00091 19.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Cutinase PF01083.22 KZN88422.1 - 0.0017 18.3 0.0 0.0043 17.0 0.0 1.6 1 0 0 1 1 1 1 Cutinase Ser_hydrolase PF06821.13 KZN88422.1 - 0.041 13.7 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Esterase PF00756.20 KZN88422.1 - 0.045 13.4 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF676 PF05057.14 KZN88422.1 - 0.1 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2974 PF11187.8 KZN88422.1 - 0.15 11.6 0.3 0.84 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) PRMT5_TIM PF17285.2 KZN88423.1 - 1.6e-72 243.8 0.0 2.1e-72 243.4 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 KZN88423.1 - 3.9e-64 215.6 0.0 8.3e-64 214.6 0.0 1.6 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 KZN88423.1 - 3.8e-57 193.0 0.2 6.2e-57 192.3 0.2 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain OB_NTP_bind PF07717.16 KZN88424.1 - 1.5e-24 86.1 0.1 1.1e-23 83.4 0.0 2.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KZN88424.1 - 1.5e-19 70.3 0.4 3.5e-19 69.1 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KZN88424.1 - 7.3e-10 39.2 0.0 2e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KZN88424.1 - 5.7e-07 29.5 0.2 1e-06 28.6 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KZN88424.1 - 0.0008 19.7 0.0 0.0027 18.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KZN88424.1 - 0.00094 18.9 0.3 0.0031 17.2 0.3 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 KZN88424.1 - 0.023 14.4 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KZN88424.1 - 0.03 14.8 0.0 0.059 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KZN88424.1 - 0.045 12.8 0.0 0.091 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 KZN88424.1 - 0.047 13.2 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KZN88424.1 - 0.12 12.9 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Flavi_DEAD PF07652.14 KZN88424.1 - 0.15 12.0 0.3 0.39 10.7 0.1 1.8 2 0 0 2 2 2 0 Flavivirus DEAD domain SAP18 PF06487.12 KZN88425.1 - 0.062 13.5 0.2 0.2 11.8 0.1 2.0 2 0 0 2 2 2 0 Sin3 associated polypeptide p18 (SAP18) DUF5082 PF16888.5 KZN88425.1 - 3.5 7.9 9.6 1.3 9.3 2.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) EF-hand_6 PF13405.6 KZN88426.1 - 2e-09 36.6 0.2 0.0019 18.0 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KZN88426.1 - 1.9e-05 25.0 0.7 0.0029 18.0 0.1 2.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KZN88426.1 - 0.0012 18.3 0.0 0.0044 16.5 0.0 1.9 2 0 0 2 2 2 1 EF hand Skp1 PF01466.19 KZN88426.1 - 0.032 14.4 1.1 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 Skp1 family, dimerisation domain ANAPC4_WD40 PF12894.7 KZN88427.1 - 5.3e-05 23.5 0.0 0.11 12.8 0.0 4.0 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain CNH PF00780.22 KZN88427.1 - 0.00095 18.9 0.1 0.029 14.0 0.1 2.4 2 0 0 2 2 2 1 CNH domain Coatomer_WDAD PF04053.14 KZN88427.1 - 0.0037 16.4 0.0 0.017 14.2 0.0 2.0 1 1 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 KZN88427.1 - 0.036 14.9 0.2 7.4 7.6 0.0 3.8 4 1 1 5 5 5 0 WD domain, G-beta repeat Hira PF07569.11 KZN88427.1 - 0.04 13.6 0.1 0.55 9.9 0.0 2.6 3 0 0 3 3 3 0 TUP1-like enhancer of split GST_N_2 PF13409.6 KZN88428.1 - 1.1e-20 73.7 0.0 1.9e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KZN88428.1 - 3.3e-15 55.8 0.0 8.4e-15 54.6 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KZN88428.1 - 4e-05 23.8 0.0 0.00011 22.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KZN88428.1 - 5.9e-05 23.4 0.0 0.001 19.4 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KZN88428.1 - 0.00054 20.1 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DSPc PF00782.20 KZN88429.1 - 1e-29 103.0 0.0 4e-22 78.5 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KZN88429.1 - 0.00013 21.7 0.0 0.0034 17.0 0.0 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KZN88429.1 - 0.077 13.1 0.0 0.42 10.7 0.1 2.1 2 0 0 2 2 2 0 Inositol hexakisphosphate Mlh1_C PF16413.5 KZN88430.1 - 1.5e-98 329.5 0.0 2.4e-98 328.8 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KZN88430.1 - 4.1e-33 113.6 0.2 6.8e-33 112.9 0.2 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KZN88430.1 - 1e-13 51.3 0.0 2.3e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KZN88430.1 - 1.1e-07 32.3 0.0 2.9e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RPN1_RPN2_N PF17781.1 KZN88432.1 - 8.6e-117 389.9 1.2 1.1e-116 389.6 0.6 1.5 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KZN88432.1 - 6.5e-30 102.9 0.0 1.2e-29 102.1 0.0 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KZN88432.1 - 5.7e-18 64.4 15.8 2.8e-05 24.3 0.2 7.6 7 0 0 7 7 7 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KZN88432.1 - 6.7e-05 23.2 0.5 1.4 9.3 0.0 4.3 3 2 0 3 3 3 2 HEAT repeats RIO1 PF01163.22 KZN88433.1 - 1.2e-40 139.1 0.7 1.5e-28 99.6 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.11 KZN88433.1 - 1.5e-30 105.2 0.0 5.9e-30 103.3 0.0 1.9 2 0 0 2 2 2 1 Rio2, N-terminal Kdo PF06293.14 KZN88433.1 - 5.6e-07 29.1 0.0 3e-05 23.5 0.0 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KZN88433.1 - 4.9e-06 26.6 0.0 0.026 14.4 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Astro_capsid_p PF12226.8 KZN88433.1 - 1.4 8.0 5.5 2.1 7.4 5.5 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CDC45 PF02724.14 KZN88433.1 - 3 6.0 11.3 4.4 5.5 11.3 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KZN88433.1 - 3.1 7.0 11.8 4.9 6.4 11.8 1.2 1 0 0 1 1 1 0 NOA36 protein Kdo PF06293.14 KZN88435.1 - 0.0016 17.8 0.0 0.0048 16.3 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KZN88435.1 - 0.0019 18.1 4.2 0.012 15.6 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Ribosomal_L23 PF00276.20 KZN88436.1 - 2.2e-10 40.7 0.0 4e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 Lon_C PF05362.13 KZN88437.1 - 7.3e-70 234.7 0.2 2.3e-69 233.0 0.1 1.9 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KZN88437.1 - 1.3e-30 106.8 0.0 2.4e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KZN88437.1 - 4.7e-23 82.1 0.0 2.6e-22 79.6 0.0 2.4 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 KZN88437.1 - 1.4e-08 34.6 0.1 1.3e-07 31.5 0.0 2.3 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 KZN88437.1 - 1.6e-07 31.4 0.0 5e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KZN88437.1 - 3e-06 27.7 0.8 1.2e-05 25.7 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 KZN88437.1 - 3.1e-05 23.8 0.0 8.8e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KZN88437.1 - 8.3e-05 21.9 0.0 0.00016 21.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KZN88437.1 - 0.00017 21.9 0.2 0.0041 17.4 0.0 3.2 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KZN88437.1 - 0.00047 19.9 0.1 0.0014 18.4 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KZN88437.1 - 0.00059 20.0 0.0 0.0022 18.1 0.0 2.1 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KZN88437.1 - 0.0011 18.7 0.0 0.0029 17.4 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 KZN88437.1 - 0.0018 18.5 0.0 0.0043 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KZN88437.1 - 0.017 14.6 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 KZN88437.1 - 0.02 14.9 0.0 0.05 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KZN88437.1 - 0.03 14.7 0.0 0.28 11.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_11 PF13086.6 KZN88437.1 - 0.031 14.1 0.6 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KZN88437.1 - 0.031 14.8 0.0 0.081 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KZN88437.1 - 0.035 13.6 0.0 0.085 12.3 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein ATPase_2 PF01637.18 KZN88437.1 - 0.042 13.8 0.1 1.7 8.5 0.0 2.9 2 1 1 3 3 2 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KZN88437.1 - 0.052 13.1 0.1 0.16 11.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 KZN88437.1 - 0.053 12.9 0.1 0.13 11.6 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KZN88437.1 - 0.057 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_PrkA PF08298.11 KZN88437.1 - 0.074 12.0 0.0 0.48 9.3 0.0 2.0 2 0 0 2 2 2 0 PrkA AAA domain AAA_30 PF13604.6 KZN88437.1 - 0.094 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KZN88437.1 - 0.099 12.0 0.0 0.29 10.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial TniB protein TsaE PF02367.17 KZN88437.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 KZN88437.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_19 PF13245.6 KZN88437.1 - 0.13 12.6 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KZN88437.1 - 0.55 10.7 0.0 0.55 10.7 0.0 2.9 2 1 0 2 2 1 0 AAA domain CCDC-167 PF15188.6 KZN88437.1 - 0.6 10.5 4.1 0.74 10.2 1.0 2.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Porphobil_deam PF01379.20 KZN88438.1 - 7.2e-73 244.4 0.0 1.2e-72 243.7 0.0 1.3 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KZN88438.1 - 7.4e-17 61.5 0.6 1.8e-16 60.3 0.3 1.8 2 0 0 2 2 2 1 Porphobilinogen deaminase, C-terminal domain Fibrinogen_aC PF12160.8 KZN88438.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Fibrinogen alpha C domain TAP42 PF04177.12 KZN88439.1 - 2.5e-102 342.3 2.2 2.9e-102 342.1 2.2 1.0 1 0 0 1 1 1 1 TAP42-like family MucBP PF06458.12 KZN88439.1 - 0.18 12.8 0.1 0.42 11.6 0.1 1.7 1 0 0 1 1 1 0 MucBP domain Ribonuclease_3 PF00636.26 KZN88440.1 - 1e-43 148.3 0.0 1.7e-20 73.6 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KZN88440.1 - 2.2e-27 95.7 0.0 3.5e-14 53.1 0.0 3.7 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.14 KZN88440.1 - 3.9e-20 71.8 0.1 2e-19 69.6 0.1 2.2 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.31 KZN88440.1 - 7.4e-17 61.7 0.0 2.1e-16 60.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KZN88440.1 - 1.4e-13 51.2 0.0 4.1e-13 49.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KZN88440.1 - 3.6e-10 39.9 0.0 7.8e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.26 KZN88440.1 - 0.015 16.0 0.3 5.4 7.8 0.0 2.7 2 0 0 2 2 2 0 Double-stranded RNA binding motif AAA_22 PF13401.6 KZN88440.1 - 0.11 12.8 0.1 0.48 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KZN88440.1 - 0.16 11.2 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DHC_N1 PF08385.12 KZN88441.1 - 2.6e-124 416.0 5.2 2.6e-124 416.0 5.2 5.9 7 0 0 7 7 7 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 KZN88441.1 - 2.2e-123 411.4 0.0 1.7e-122 408.5 0.0 2.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KZN88441.1 - 1.3e-113 380.1 6.7 1.3e-113 380.1 6.7 4.1 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 KZN88441.1 - 5.7e-75 251.2 1.0 5.7e-75 251.2 1.0 3.7 3 1 1 4 4 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 KZN88441.1 - 1.8e-65 220.8 0.0 4.9e-65 219.4 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.7 KZN88441.1 - 2.5e-42 145.1 8.2 5.2e-42 144.1 8.2 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 KZN88441.1 - 7e-42 143.0 0.0 1.6e-36 125.5 0.0 4.7 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_5 PF07728.14 KZN88441.1 - 8.9e-32 110.0 0.3 6.6e-10 39.1 0.0 6.6 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_lid_11 PF18198.1 KZN88441.1 - 3.5e-30 105.0 0.0 7.8e-30 103.8 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KZN88441.1 - 4.5e-30 104.2 0.1 8.9e-25 87.1 0.0 4.7 5 0 0 5 5 4 2 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 KZN88441.1 - 8.3e-18 64.7 0.0 4.3e-17 62.4 0.0 2.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 KZN88441.1 - 1e-14 55.1 0.0 0.0001 22.8 0.0 4.8 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KZN88441.1 - 8.8e-14 52.0 2.8 0.0081 16.4 0.0 6.4 6 0 0 6 6 5 2 AAA domain AAA_18 PF13238.6 KZN88441.1 - 7e-10 39.6 0.2 0.047 14.2 0.0 5.3 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.6 KZN88441.1 - 1.6e-08 34.8 1.1 0.47 10.6 0.1 5.0 4 0 0 4 4 4 3 AAA domain AAA_16 PF13191.6 KZN88441.1 - 3.2e-08 34.2 2.4 1.2 9.5 0.0 7.3 7 0 0 7 7 6 1 AAA ATPase domain ABC_tran PF00005.27 KZN88441.1 - 6.1e-06 26.8 0.5 1.1 9.7 0.1 5.2 4 0 0 4 4 3 2 ABC transporter T2SSE PF00437.20 KZN88441.1 - 9.5e-06 24.9 0.0 0.012 14.7 0.0 3.4 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_lid_1 PF17857.1 KZN88441.1 - 1.7e-05 25.0 0.1 0.00048 20.3 0.0 3.2 3 0 0 3 3 2 1 AAA+ lid domain AAA_29 PF13555.6 KZN88441.1 - 0.00018 21.2 0.0 2.3 8.0 0.0 3.8 3 0 0 3 3 3 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 KZN88441.1 - 0.00022 20.7 0.9 0.59 9.5 0.0 3.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KZN88441.1 - 0.00046 20.5 0.3 0.21 11.9 0.0 4.2 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KZN88441.1 - 0.00055 19.7 0.4 23 4.7 0.0 4.7 4 0 0 4 4 4 0 AAA domain DUF3867 PF12983.7 KZN88441.1 - 0.002 18.2 0.3 0.002 18.2 0.3 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3867) AAA_25 PF13481.6 KZN88441.1 - 0.002 17.7 0.0 0.46 10.0 0.0 3.6 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 KZN88441.1 - 0.0037 17.0 1.1 0.54 10.0 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_24 PF13479.6 KZN88441.1 - 0.0054 16.5 1.3 22 4.7 0.0 4.7 5 0 0 5 5 4 0 AAA domain Rad17 PF03215.15 KZN88441.1 - 0.0061 16.5 1.5 5.7 6.8 0.0 4.4 5 0 0 5 5 3 0 Rad17 P-loop domain Zeta_toxin PF06414.12 KZN88441.1 - 0.007 15.7 0.7 5.8 6.1 0.2 3.9 4 0 0 4 4 4 0 Zeta toxin FtsK_SpoIIIE PF01580.18 KZN88441.1 - 0.0088 15.4 0.0 2.1 7.7 0.0 3.5 3 0 0 3 3 3 1 FtsK/SpoIIIE family RNA_helicase PF00910.22 KZN88441.1 - 0.013 15.9 0.2 32 5.0 0.0 4.6 4 0 0 4 4 4 0 RNA helicase G-gamma PF00631.22 KZN88441.1 - 0.13 12.3 0.1 1.9 8.6 0.0 3.0 2 0 0 2 2 2 0 GGL domain MbeB_N PF04837.12 KZN88441.1 - 0.14 12.5 2.2 1.8 9.0 0.1 3.4 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Vps23_core PF09454.10 KZN88441.1 - 0.15 12.1 0.3 9.3 6.3 0.4 2.9 2 0 0 2 2 2 0 Vps23 core domain COG2 PF06148.11 KZN88441.1 - 0.23 11.5 0.0 0.23 11.5 0.0 5.8 5 0 0 5 5 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Jnk-SapK_ap_N PF09744.9 KZN88441.1 - 2 8.6 20.8 0.18 12.0 0.5 4.1 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 Phage_GP20 PF06810.11 KZN88441.1 - 2.3 8.0 23.8 0.7 9.7 0.4 4.1 4 0 0 4 4 3 0 Phage minor structural protein GP20 BRE1 PF08647.11 KZN88441.1 - 2.8 8.1 18.9 0.0069 16.4 1.2 4.7 3 0 0 3 3 2 0 BRE1 E3 ubiquitin ligase Atg14 PF10186.9 KZN88441.1 - 3.1 6.8 12.7 1.2 8.1 5.1 2.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 WXG100 PF06013.12 KZN88441.1 - 3.1 8.1 5.7 11 6.3 1.1 4.5 3 0 0 3 3 3 0 Proteins of 100 residues with WXG zf-C4H2 PF10146.9 KZN88441.1 - 7.3 6.8 7.1 4.7 7.4 0.0 3.2 2 0 0 2 2 1 0 Zinc finger-containing protein ERM PF00769.19 KZN88441.1 - 7.8 6.2 30.6 2 8.1 2.5 3.5 3 0 0 3 3 2 0 Ezrin/radixin/moesin family RPW8 PF05659.11 KZN88441.1 - 8.5 6.1 7.3 1.4e+02 2.2 0.0 4.1 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Svf1_C PF17187.4 KZN88442.1 - 1.3e-61 207.2 0.2 3e-61 206.0 0.0 1.7 2 0 0 2 2 2 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 KZN88442.1 - 3.1e-59 199.7 0.1 4.4e-59 199.2 0.1 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Ribosomal_L11 PF00298.19 KZN88443.1 - 2.6e-26 91.9 0.0 3.8e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KZN88443.1 - 2.8e-26 91.1 0.1 4.5e-26 90.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Pkinase PF00069.25 KZN88444.1 - 4e-45 154.2 0.0 1e-41 143.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KZN88444.1 - 5.9e-19 68.4 0.0 1e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KZN88444.1 - 0.034 14.1 0.4 0.07 13.0 0.4 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KZN88444.1 - 0.054 12.4 0.0 0.14 11.1 0.0 1.6 1 0 0 1 1 1 0 Haspin like kinase domain Mito_carr PF00153.27 KZN88445.1 - 1.4e-40 137.1 5.3 2.1e-15 56.4 0.1 3.7 3 2 0 3 3 3 3 Mitochondrial carrier protein Cupin_5 PF06172.11 KZN88446.1 - 3.2e-51 173.2 0.0 3.9e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) CaMKII_AD PF08332.10 KZN88446.1 - 0.022 14.9 0.0 0.038 14.1 0.0 1.2 1 0 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II association domain DUF3337 PF11816.8 KZN88447.1 - 7.2e-55 185.5 0.0 1.3e-54 184.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 KZN88447.1 - 6.2e-18 64.8 14.8 5.9e-05 23.8 0.2 7.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN88447.1 - 0.0025 18.1 0.2 0.3 11.4 0.1 3.5 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KZN88447.1 - 0.0033 16.5 0.0 0.13 11.2 0.0 2.2 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KZN88447.1 - 0.12 11.0 0.4 1.1 7.9 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 TPR_2 PF07719.17 KZN88448.1 - 4.4e-14 51.4 4.7 0.0059 16.6 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KZN88448.1 - 3.8e-08 32.8 0.9 0.21 11.5 0.0 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KZN88448.1 - 2.2e-06 28.1 9.7 0.0042 17.6 0.2 5.3 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 KZN88448.1 - 7.1e-05 23.1 12.0 1.3 9.9 0.1 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KZN88448.1 - 7.7e-05 22.3 1.7 0.072 12.8 0.0 4.7 4 0 0 4 4 4 1 TPR repeat TPR_12 PF13424.6 KZN88448.1 - 0.00013 22.2 11.8 0.007 16.6 1.4 4.9 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KZN88448.1 - 0.0028 18.3 21.2 2.4 9.2 0.0 8.3 9 1 1 10 10 9 2 Tetratricopeptide repeat Ofd1_CTDD PF10637.9 KZN88448.1 - 0.0031 16.9 0.2 0.038 13.3 0.0 2.0 2 0 0 2 2 2 1 Oxoglutarate and iron-dependent oxygenase degradation C-term TPR_7 PF13176.6 KZN88448.1 - 0.0035 17.3 5.9 9.3 6.5 0.2 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 KZN88448.1 - 0.011 16.4 20.0 0.62 10.8 0.8 6.9 7 1 0 7 7 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 KZN88448.1 - 0.14 12.6 0.4 1.2e+02 3.4 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KZN88448.1 - 0.27 11.1 7.8 1.6 8.7 0.1 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KZN88448.1 - 1.8 9.0 8.9 15 6.1 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat ATP_bind_3 PF01171.20 KZN88450.1 - 1.6e-37 129.1 0.0 8.8e-37 126.6 0.0 2.1 1 1 0 1 1 1 1 PP-loop family RhoGEF PF00621.20 KZN88451.1 - 5.8e-21 75.6 0.0 2.7e-20 73.4 0.0 2.0 2 0 0 2 2 2 1 RhoGEF domain DUF3507 PF12015.8 KZN88451.1 - 2.7e-06 27.2 0.0 5.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) Nod1 PF17114.5 KZN88451.1 - 0.00035 20.7 0.0 0.0011 19.1 0.0 1.9 2 0 0 2 2 2 1 Gef2-related medial cortical node protein Nod1 FAM184 PF15665.5 KZN88451.1 - 0.0058 16.4 1.1 0.019 14.7 1.1 1.8 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B Sec7 PF01369.20 KZN88452.1 - 1.3e-60 204.3 0.0 2e-60 203.6 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KZN88452.1 - 1.2e-18 67.5 2.2 4.8e-18 65.6 0.0 3.1 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal TAN PF11640.8 KZN88452.1 - 0.15 12.2 0.8 59 3.8 0.0 4.3 4 0 0 4 4 4 0 Telomere-length maintenance and DNA damage repair DUF4351 PF14261.6 KZN88452.1 - 0.28 11.3 1.1 1.1 9.3 1.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) TPR_14 PF13428.6 KZN88453.1 - 7e-15 54.5 17.0 0.45 11.5 0.0 11.7 9 3 5 14 14 13 4 Tetratricopeptide repeat Suf PF05843.14 KZN88453.1 - 3e-09 37.3 15.8 0.033 14.2 0.1 6.6 4 1 1 6 6 6 4 Suppressor of forked protein (Suf) TPR_19 PF14559.6 KZN88453.1 - 3.8e-09 36.9 1.1 0.81 10.2 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KZN88453.1 - 4e-08 33.3 14.1 0.12 12.4 0.1 7.2 6 2 1 7 7 7 2 Mad3/BUB1 homology region 1 TPR_8 PF13181.6 KZN88453.1 - 4.9e-08 32.6 7.2 0.039 14.2 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 KZN88453.1 - 9.8e-08 31.5 4.1 0.0002 20.7 2.1 4.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KZN88453.1 - 2.1e-06 27.9 5.2 1.3 9.4 0.0 6.8 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KZN88453.1 - 2.3e-06 27.2 15.9 0.97 9.7 0.0 7.9 9 0 0 9 9 9 2 Tetratricopeptide repeat SNAP PF14938.6 KZN88453.1 - 5.1e-05 22.8 2.9 0.076 12.4 0.1 4.2 5 1 0 5 5 5 2 Soluble NSF attachment protein, SNAP TPR_17 PF13431.6 KZN88453.1 - 0.0016 18.7 6.9 0.067 13.6 0.0 6.0 7 0 0 7 7 5 1 Tetratricopeptide repeat MIT PF04212.18 KZN88453.1 - 0.0043 17.1 0.3 0.71 10.0 0.1 4.4 6 0 0 6 6 5 1 MIT (microtubule interacting and transport) domain NRDE-2 PF08424.10 KZN88453.1 - 0.0083 15.3 10.8 0.076 12.1 0.3 4.9 2 2 2 4 4 4 2 NRDE-2, necessary for RNA interference RPN7 PF10602.9 KZN88453.1 - 0.02 14.6 0.0 0.41 10.3 0.0 2.9 3 1 0 3 3 3 0 26S proteasome subunit RPN7 HAT PF02184.16 KZN88453.1 - 0.083 12.9 4.4 3.2 7.8 0.0 5.4 7 0 0 7 7 6 0 HAT (Half-A-TPR) repeat TPR_6 PF13174.6 KZN88453.1 - 0.67 10.7 11.7 2.5 8.9 0.0 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat Esterase_phd PF10503.9 KZN88454.1 - 4.4e-05 23.1 0.2 7.8e-05 22.3 0.2 1.6 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KZN88454.1 - 0.023 14.2 0.4 0.057 12.9 0.4 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family MatE PF01554.18 KZN88455.1 - 2.3e-38 131.4 25.1 4.1e-29 101.3 9.3 2.9 2 0 0 2 2 2 2 MatE TFCD_C PF12612.8 KZN88455.1 - 6.5e-34 117.4 0.2 2.1e-33 115.8 0.1 2.0 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 KZN88455.1 - 8.9e-05 22.4 5.5 1.1 9.7 0.0 7.3 7 0 0 7 7 7 1 HEAT repeat IFRD PF05004.13 KZN88455.1 - 0.00096 18.3 1.5 0.0028 16.8 0.1 2.4 3 0 0 3 3 3 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.6 KZN88455.1 - 0.0043 17.4 0.2 6.2 7.3 0.0 4.7 5 0 0 5 5 5 1 HEAT repeats Pkinase PF00069.25 KZN88457.1 - 8.5e-58 195.8 0.0 1.4e-57 195.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN88457.1 - 2.7e-34 118.6 0.0 4.6e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 KZN88457.1 - 1.6e-28 98.6 16.5 1e-15 57.6 4.2 2.8 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 KZN88457.1 - 4.1e-20 71.4 30.3 3e-12 46.2 9.5 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KZN88457.1 - 1.9e-14 54.1 0.8 1.9e-13 50.9 1.5 2.4 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 KZN88457.1 - 8.1e-06 26.1 0.0 1.6e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 KZN88457.1 - 0.16 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 KZN88457.1 - 0.21 10.5 0.5 0.67 8.8 0.1 1.7 1 1 0 2 2 2 0 Haspin like kinase domain TFIIA PF03153.13 KZN88457.1 - 2.5 8.0 16.8 5.5 6.9 16.8 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Uds1 PF15456.6 KZN88457.1 - 3.1 8.0 5.3 1.1 9.4 0.6 2.4 2 0 0 2 2 2 0 Up-regulated During Septation zf-RING_9 PF13901.6 KZN88457.1 - 8.2 6.3 23.4 3.1 7.7 8.6 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon eIF-1a PF01176.19 KZN88458.1 - 4.4e-16 58.5 0.4 6.4e-16 57.9 0.4 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ALG3 PF05208.13 KZN88459.1 - 1.5e-140 468.7 18.0 1.7e-140 468.5 18.0 1.0 1 0 0 1 1 1 1 ALG3 protein COA2 PF17051.5 KZN88460.1 - 0.013 15.6 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase assembly factor 2 NSP2-B_epitope PF14757.6 KZN88460.1 - 0.02 14.6 0.2 0.027 14.2 0.2 1.1 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein Metallophos PF00149.28 KZN88461.1 - 1.4e-30 107.3 0.0 4.2e-22 79.6 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KZN88461.1 - 0.19 12.2 0.1 0.49 10.9 0.1 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Fungal_trans PF04082.18 KZN88462.1 - 1.2e-42 145.8 0.3 2.3e-42 144.9 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN88462.1 - 4.6e-08 33.1 8.2 9.2e-08 32.1 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.29 KZN88462.1 - 0.0026 17.6 5.7 0.0032 17.3 4.5 1.8 2 0 0 2 2 2 1 PHD-finger DUF3473 PF11959.8 KZN88462.1 - 0.039 14.0 0.0 0.088 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3473) DNA_ligase_A_M PF01068.21 KZN88464.1 - 5.9e-47 160.0 0.2 3.6e-46 157.4 0.0 2.5 4 0 0 4 4 4 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KZN88464.1 - 4.6e-46 157.3 0.0 4.4e-45 154.1 0.0 2.5 3 0 0 3 3 3 1 DNA ligase N terminus BRCT_2 PF16589.5 KZN88464.1 - 6.6e-19 68.1 0.1 2e-13 50.5 0.0 2.8 2 1 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 KZN88464.1 - 9.6e-18 64.6 0.7 3.3e-17 62.9 0.0 2.4 2 0 0 2 2 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KZN88464.1 - 1.8e-17 64.1 0.0 5.2e-17 62.6 0.0 1.9 1 0 0 1 1 1 1 RNA ligase BRCT PF00533.26 KZN88464.1 - 1.3e-06 28.7 0.1 0.00047 20.5 0.0 3.0 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.8 KZN88464.1 - 2.7e-06 27.4 0.1 5.7e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 DNA ligase IV LIG3_BRCT PF16759.5 KZN88464.1 - 6.9e-06 26.3 0.4 0.016 15.5 0.1 2.5 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 KZN88464.1 - 0.00013 21.8 0.0 0.02 14.8 0.1 2.5 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain EccE PF11203.8 KZN88464.1 - 0.047 14.0 0.7 0.21 11.9 0.1 2.4 3 0 0 3 3 3 0 Putative type VII ESX secretion system translocon, EccE mRNA_cap_enzyme PF01331.19 KZN88464.1 - 0.075 12.9 0.1 0.53 10.1 0.0 2.6 1 1 1 2 2 2 0 mRNA capping enzyme, catalytic domain Transketolase_C PF02780.20 KZN88464.1 - 0.17 11.8 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 Transketolase, C-terminal domain Fungal_trans PF04082.18 KZN88465.1 - 5e-22 78.2 2.0 1e-21 77.2 2.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KZN88465.1 - 1.5e-06 28.3 16.5 0.00077 19.8 3.0 3.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KZN88465.1 - 1.9e-06 28.2 15.5 0.0087 16.8 2.4 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KZN88465.1 - 2.8e-06 27.5 5.2 2.8e-06 27.5 5.2 3.2 3 0 0 3 3 3 1 Zinc-finger double domain Zn_clus PF00172.18 KZN88465.1 - 2.1e-05 24.6 7.9 2.1e-05 24.6 7.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2HE PF16278.5 KZN88465.1 - 0.0036 17.7 5.5 0.033 14.6 0.4 2.7 1 1 1 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 KZN88465.1 - 0.012 16.0 2.4 0.026 14.9 0.4 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KZN88465.1 - 0.014 15.7 5.3 2 8.8 0.5 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 KZN88465.1 - 0.18 12.5 2.8 2.4 8.9 2.4 2.6 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf_C2H2_ZHX PF18387.1 KZN88465.1 - 3.4 7.4 6.5 1.4 8.6 1.2 2.5 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain EF-hand_4 PF12763.7 KZN88466.1 - 0.00074 19.4 0.1 0.0014 18.6 0.1 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Zn_clus PF00172.18 KZN88467.1 - 6.4e-07 29.4 6.3 1.7e-06 28.0 6.3 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN88467.1 - 8.9e-06 24.9 0.1 2e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Spb1_C PF07780.12 KZN88469.1 - 1.5e-81 273.0 37.4 1.5e-81 273.0 37.4 3.9 2 1 1 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 KZN88469.1 - 3.2e-56 190.2 0.0 5.6e-56 189.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KZN88469.1 - 3.5e-50 170.0 8.8 3.5e-50 170.0 8.8 5.1 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 KZN88469.1 - 0.026 14.4 0.0 0.083 12.7 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 KZN88470.1 - 9.4e-78 260.4 0.0 1.3e-77 260.0 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Med9 PF07544.13 KZN88470.1 - 0.069 13.2 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 ATG16 PF08614.11 KZN88471.1 - 2e-58 198.0 18.2 2.2e-58 197.8 18.2 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Lebercilin PF15619.6 KZN88471.1 - 0.00068 19.4 15.6 0.001 18.8 15.6 1.3 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Golgin_A5 PF09787.9 KZN88471.1 - 0.00097 18.7 5.8 0.00098 18.7 5.8 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 HAUS-augmin3 PF14932.6 KZN88471.1 - 0.0043 16.7 6.2 0.0043 16.7 6.2 1.6 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 3 DUF4201 PF13870.6 KZN88471.1 - 0.0086 15.8 11.5 0.0086 15.8 11.5 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) UPF0242 PF06785.11 KZN88471.1 - 0.03 14.5 13.8 0.065 13.3 3.6 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus SOGA PF11365.8 KZN88471.1 - 0.055 14.6 11.3 0.089 13.9 10.6 1.7 1 1 0 1 1 1 0 Protein SOGA Spc7 PF08317.11 KZN88471.1 - 0.084 11.7 12.2 0.52 9.1 2.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 KZN88471.1 - 0.089 12.8 3.6 4.8 7.2 3.6 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) MscS_porin PF12795.7 KZN88471.1 - 0.19 11.3 24.2 0.38 10.3 17.2 2.9 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF3450 PF11932.8 KZN88471.1 - 0.28 10.5 13.2 0.045 13.1 8.8 1.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Nup54 PF13874.6 KZN88471.1 - 0.29 11.2 11.9 0.18 11.9 4.0 2.3 2 1 1 3 3 2 0 Nucleoporin complex subunit 54 APG6_N PF17675.1 KZN88471.1 - 0.3 11.6 16.5 0.54 10.8 16.3 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region FAM76 PF16046.5 KZN88471.1 - 0.41 10.0 4.5 0.48 9.7 4.5 1.2 1 0 0 1 1 1 0 FAM76 protein GAS PF13851.6 KZN88471.1 - 0.49 9.7 13.8 0.85 8.9 12.4 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 KZN88471.1 - 0.51 9.7 14.2 0.95 8.7 14.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2203 PF09969.9 KZN88471.1 - 0.56 10.9 6.0 0.12 13.1 1.9 2.0 2 1 1 3 3 2 0 Uncharacterized conserved protein (DUF2203) Nbl1_Borealin_N PF10444.9 KZN88471.1 - 0.6 9.8 5.4 1.9 8.2 0.6 2.7 2 1 0 2 2 2 0 Nbl1 / Borealin N terminal Cep57_MT_bd PF06657.13 KZN88471.1 - 0.83 10.1 10.0 7.4 7.1 1.4 3.4 1 1 3 4 4 4 0 Centrosome microtubule-binding domain of Cep57 Fez1 PF06818.15 KZN88471.1 - 0.85 10.0 14.1 1.9 8.9 5.8 2.3 1 1 1 2 2 2 0 Fez1 Exonuc_VII_L PF02601.15 KZN88471.1 - 1.3 8.5 9.4 1.5 8.3 9.1 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit FlaC_arch PF05377.11 KZN88471.1 - 1.3 9.4 4.7 34 4.9 0.2 2.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Cnn_1N PF07989.11 KZN88471.1 - 2.1 8.5 12.5 0.79 9.9 4.3 3.0 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 YabA PF06156.13 KZN88471.1 - 2.5 8.8 12.3 2.6 8.7 3.1 2.4 2 1 1 3 3 2 0 Initiation control protein YabA BRE1 PF08647.11 KZN88471.1 - 2.8 8.1 14.0 1.1 9.3 10.5 2.1 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DHR10 PF18595.1 KZN88471.1 - 2.8 8.0 21.8 2.9 8.0 9.6 2.5 2 1 1 3 3 2 0 Designed helical repeat protein 10 domain Prefoldin_2 PF01920.20 KZN88471.1 - 2.9 7.9 11.1 1.7 8.6 0.8 2.5 2 1 1 3 3 2 0 Prefoldin subunit ERM PF00769.19 KZN88471.1 - 7.3 6.3 21.7 1.1 9.0 9.6 2.5 1 1 2 3 3 3 0 Ezrin/radixin/moesin family ABC_tran_CTD PF16326.5 KZN88471.1 - 7.5 6.9 14.7 0.65 10.3 4.0 3.7 3 1 1 4 4 4 0 ABC transporter C-terminal domain Ras PF00071.22 KZN88472.1 - 1e-56 191.0 0.1 1.2e-56 190.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KZN88472.1 - 2.2e-32 111.8 0.0 3.1e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KZN88472.1 - 1.1e-12 47.8 0.0 1.3e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KZN88472.1 - 5.7e-07 29.6 0.0 9.7e-07 28.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KZN88472.1 - 7e-06 25.7 0.0 0.00017 21.2 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KZN88472.1 - 1.4e-05 24.6 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KZN88472.1 - 0.00019 21.4 0.3 0.0067 16.3 0.2 2.4 1 1 1 3 3 3 1 RsgA GTPase ATP_bind_1 PF03029.17 KZN88472.1 - 0.0015 18.3 0.3 0.037 13.8 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 KZN88472.1 - 0.0019 17.9 0.1 0.17 11.6 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KZN88472.1 - 0.0021 17.7 0.0 0.011 15.3 0.0 1.9 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 KZN88472.1 - 0.0055 16.0 0.1 0.086 12.1 0.0 2.2 2 0 0 2 2 2 1 Septin AAA_16 PF13191.6 KZN88472.1 - 0.0087 16.4 0.0 0.015 15.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KZN88472.1 - 0.014 15.4 0.0 0.033 14.2 0.0 1.7 2 1 1 3 3 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KZN88472.1 - 0.015 15.5 0.0 0.03 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KZN88472.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KZN88472.1 - 0.028 13.8 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 KZN88472.1 - 0.039 13.5 0.1 0.065 12.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 KZN88472.1 - 0.064 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 KZN88472.1 - 0.1 12.5 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 KZN88472.1 - 0.1 11.7 0.3 0.18 11.0 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 KZN88472.1 - 0.13 12.1 0.9 0.19 11.6 0.1 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TniB PF05621.11 KZN88472.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein EamA PF00892.20 KZN88473.1 - 2e-09 37.8 38.5 8e-07 29.3 4.6 3.1 3 0 0 3 3 3 3 EamA-like transporter family DUF3955 PF13127.6 KZN88473.1 - 4e-07 29.7 2.9 4.2e-07 29.7 0.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3955) UAA PF08449.11 KZN88473.1 - 1.5e-05 24.3 9.6 2.4e-05 23.7 9.6 1.2 1 0 0 1 1 1 1 UAA transporter family SLC35F PF06027.12 KZN88473.1 - 6.3e-05 22.6 0.9 6.3e-05 22.6 0.9 2.2 2 1 1 3 3 3 1 Solute carrier family 35 PH PF00169.29 KZN88474.1 - 7.1e-28 97.2 0.0 1.3e-12 48.1 0.0 2.2 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 KZN88474.1 - 7.3e-10 39.2 0.2 6.7e-05 23.2 0.0 4.0 2 2 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 KZN88474.1 - 2.5e-08 34.3 0.7 0.0054 17.1 0.1 3.4 2 2 0 2 2 2 2 Pleckstrin homology domain Glyco_transf_15 PF01793.16 KZN88475.1 - 8.4e-95 317.7 11.1 3.4e-94 315.7 11.1 1.8 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Cyt-b5 PF00173.28 KZN88476.1 - 1.5e-12 47.5 0.0 2.6e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MFS_1 PF07690.16 KZN88478.1 - 2.1e-26 92.7 48.4 2.1e-26 92.7 48.4 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Otopetrin PF03189.13 KZN88478.1 - 0.026 13.3 2.7 0.047 12.5 2.7 1.4 1 0 0 1 1 1 0 Otopetrin Phage_holin_5_1 PF06946.11 KZN88478.1 - 0.59 10.5 6.3 0.63 10.5 0.7 3.5 3 1 0 3 3 3 0 Bacteriophage A118-like holin, Hol118 Peptidase_S76 PF13611.6 KZN88479.1 - 0.034 14.5 0.1 0.13 12.6 0.0 2.0 2 0 0 2 2 2 0 Serine peptidase of plant viral polyprotein, P1 Ran_BP1 PF00638.18 KZN88480.1 - 1.9e-48 163.7 2.6 1.9e-48 163.7 2.6 1.7 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.23 KZN88480.1 - 2.2e-05 24.3 0.5 0.00012 22.0 0.5 1.9 1 1 0 1 1 1 1 WH1 domain VID27_PH PF17747.1 KZN88480.1 - 0.001 19.3 0.1 0.0015 18.8 0.1 1.2 1 0 0 1 1 1 1 VID27 PH-like domain CDC27 PF09507.10 KZN88480.1 - 0.054 12.9 23.4 0.076 12.4 23.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 YEATS PF03366.16 KZN88481.1 - 2.7e-19 68.9 0.2 5.1e-19 68.0 0.2 1.5 1 0 0 1 1 1 1 YEATS family BET PF17035.5 KZN88481.1 - 8.4e-06 25.9 0.1 1.6e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Phosducin PF02114.16 KZN88482.1 - 1.1e-15 57.3 0.0 2.9e-14 52.7 0.0 2.1 1 1 0 1 1 1 1 Phosducin SPX PF03105.19 KZN88482.1 - 0.12 12.3 6.8 0.16 11.9 6.8 1.1 1 0 0 1 1 1 0 SPX domain Clathrin_lg_ch PF01086.17 KZN88482.1 - 0.13 12.3 3.9 0.2 11.6 3.9 1.3 1 1 0 1 1 1 0 Clathrin light chain TIMELESS_C PF05029.13 KZN88482.1 - 0.59 9.2 5.1 4.1 6.4 1.6 2.2 2 0 0 2 2 2 0 Timeless protein C terminal region WD40 PF00400.32 KZN88483.1 - 1.8e-39 133.0 20.1 9.4e-06 26.3 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN88483.1 - 7.7e-16 58.2 0.0 0.00042 20.6 0.1 5.2 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KZN88483.1 - 7e-05 22.8 0.0 0.11 12.3 0.0 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KZN88483.1 - 0.00073 19.0 0.0 0.044 13.1 0.0 3.0 2 1 1 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 KZN88483.1 - 0.031 13.2 0.2 15 4.5 0.0 3.6 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-MYND PF01753.18 KZN88484.1 - 1.8e-07 31.1 20.7 3.8e-07 30.1 20.7 1.6 1 0 0 1 1 1 1 MYND finger zf-TAZ PF02135.16 KZN88484.1 - 7.7 7.1 13.3 14 6.2 13.3 1.4 1 0 0 1 1 1 0 TAZ zinc finger DIOX_N PF14226.6 KZN88485.1 - 6.3e-20 72.1 0.0 8.9e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KZN88485.1 - 1.1e-12 48.3 0.0 2.8e-12 47.0 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MKT1_C PF12246.8 KZN88486.1 - 1.4e-77 260.2 0.0 2.8e-77 259.2 0.0 1.5 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 KZN88486.1 - 2.5e-29 101.5 0.0 8.1e-29 99.8 0.0 1.9 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 KZN88486.1 - 0.00017 22.0 0.0 0.00032 21.1 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KZN88486.1 - 0.0002 21.6 0.0 0.00044 20.5 0.0 1.5 1 0 0 1 1 1 1 XPG I-region DUF3665 PF12427.8 KZN88486.1 - 0.096 12.4 0.1 0.28 10.9 0.1 1.8 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase Thioredoxin PF00085.20 KZN88487.1 - 1.5e-57 192.0 0.0 7.3e-28 96.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 KZN88487.1 - 3.2e-22 79.2 1.5 7e-22 78.1 1.5 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 KZN88487.1 - 3.3e-18 66.1 0.1 6.5e-08 33.0 0.0 2.8 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KZN88487.1 - 7.1e-15 55.1 0.0 1.1e-06 28.2 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KZN88487.1 - 2.3e-10 40.5 0.0 2.2e-05 24.5 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KZN88487.1 - 3.9e-08 33.5 0.0 0.0072 16.6 0.0 3.3 2 1 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 KZN88487.1 - 9.2e-08 32.1 0.0 0.015 15.2 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family TraF PF13728.6 KZN88487.1 - 6.7e-06 26.1 0.0 0.01 15.7 0.0 2.3 2 0 0 2 2 2 2 F plasmid transfer operon protein Redoxin PF08534.10 KZN88487.1 - 4e-05 23.4 0.1 0.26 11.0 0.1 2.5 2 0 0 2 2 2 2 Redoxin Glutaredoxin PF00462.24 KZN88487.1 - 0.00017 21.8 0.6 1.1 9.6 0.0 3.1 3 1 0 3 3 3 2 Glutaredoxin Thioredoxin_6 PF13848.6 KZN88487.1 - 0.00029 20.8 0.4 0.17 11.8 0.0 3.3 3 1 1 4 4 4 1 Thioredoxin-like domain HyaE PF07449.11 KZN88487.1 - 0.0011 18.9 0.0 0.8 9.7 0.0 2.6 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 KZN88487.1 - 0.0077 16.0 0.0 0.46 10.3 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin DUF836 PF05768.14 KZN88487.1 - 0.14 12.6 0.0 2.5 8.6 0.0 2.7 3 0 0 3 3 3 0 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.6 KZN88487.1 - 0.98 9.6 3.7 29 4.8 0.0 3.6 3 2 2 5 5 5 0 Thioredoxin HSBP1 PF06825.12 KZN88488.1 - 1.6e-18 66.3 0.2 2.6e-18 65.6 0.2 1.3 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.9 KZN88488.1 - 0.0017 18.2 1.2 0.0083 16.0 1.2 1.9 1 1 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin Baculo_PEP_C PF04513.12 KZN88488.1 - 0.014 15.5 0.2 0.017 15.2 0.2 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 KZN88488.1 - 0.02 14.7 0.0 0.025 14.4 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain NPV_P10 PF05531.12 KZN88488.1 - 0.022 15.2 0.3 0.034 14.6 0.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein CLZ PF16526.5 KZN88488.1 - 0.04 14.3 0.1 0.058 13.8 0.1 1.3 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Vinculin PF01044.19 KZN88488.1 - 0.043 12.1 0.0 0.049 11.9 0.0 1.0 1 0 0 1 1 1 0 Vinculin family DUF4164 PF13747.6 KZN88488.1 - 0.051 13.9 0.2 0.078 13.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Snapin_Pallidin PF14712.6 KZN88488.1 - 0.067 13.6 0.1 0.091 13.2 0.1 1.1 1 0 0 1 1 1 0 Snapin/Pallidin ABC_tran_CTD PF16326.5 KZN88488.1 - 0.12 12.7 1.3 1.2 9.4 0.5 2.0 1 1 1 2 2 2 0 ABC transporter C-terminal domain Ebp2 PF05890.12 KZN88489.1 - 9e-95 317.3 17.3 9e-95 317.3 17.3 2.0 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 TruB_N PF01509.18 KZN88490.1 - 1.9e-45 154.9 0.1 8.7e-45 152.7 0.0 2.0 2 1 1 3 3 3 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KZN88490.1 - 1.8e-06 28.0 0.0 3.8e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain Baculo_PP31 PF05311.11 KZN88490.1 - 0.036 13.5 0.0 0.1 12.1 0.0 1.7 2 1 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) DNMT1-RFD PF12047.8 KZN88491.1 - 5.3e-05 23.3 0.0 0.00019 21.5 0.0 1.9 2 0 0 2 2 2 1 Cytosine specific DNA methyltransferase replication foci domain Ycf1 PF05758.12 KZN88491.1 - 0.23 9.3 0.4 0.32 8.8 0.4 1.1 1 0 0 1 1 1 0 Ycf1 TerB_C PF15615.6 KZN88492.1 - 0.74 10.1 5.2 13 6.1 0.0 3.7 3 0 0 3 3 3 0 TerB-C domain OHCU_decarbox PF09349.10 KZN88493.1 - 1.3e-50 171.9 0.0 1.5e-50 171.7 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase DUF3135 PF11333.8 KZN88493.1 - 0.7 10.2 5.2 14 6.0 0.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3135) WD40 PF00400.32 KZN88494.1 - 2.6e-26 91.4 5.6 3.5e-06 27.6 0.1 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN88494.1 - 3e-08 33.8 0.0 0.74 10.1 0.0 5.2 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KZN88494.1 - 0.074 12.0 0.1 4.2 6.2 0.0 2.8 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KZN88494.1 - 0.1 11.9 0.1 9.5 5.5 0.0 3.5 4 0 0 4 4 4 0 Neuroblastoma-amplified sequence, N terminal SRP9-21 PF05486.12 KZN88495.1 - 8.4e-32 109.4 0.8 1.1e-31 109.1 0.8 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Ribonuc_red_sm PF00268.21 KZN88496.1 - 1.8e-122 408.2 0.9 2.1e-122 407.9 0.9 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain RE_XcyI PF09571.10 KZN88496.1 - 0.003 16.9 0.1 0.56 9.4 0.0 2.1 2 0 0 2 2 2 2 XcyI restriction endonuclease Mito_carr PF00153.27 KZN88497.1 - 1.7e-54 181.7 3.3 6.5e-19 67.6 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MotA_ExbB PF01618.16 KZN88497.1 - 0.09 12.5 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family WD40 PF00400.32 KZN88498.1 - 1.7e-13 50.8 2.7 0.0002 22.1 0.0 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN88498.1 - 7.6e-07 29.4 0.0 0.06 13.6 0.0 4.2 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KZN88498.1 - 0.019 13.3 0.0 0.03 12.6 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 KZN88498.1 - 0.077 13.0 0.1 53 3.9 0.0 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat TruB_C PF09142.11 KZN88498.1 - 0.11 12.4 0.1 0.37 10.6 0.1 1.9 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal DUF1308 PF07000.11 KZN88499.1 - 7.4e-11 42.3 0.0 6.1e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) ASD2 PF08687.11 KZN88499.1 - 0.02 14.5 1.9 0.035 13.7 1.9 1.3 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 DUF5614 PF18474.1 KZN88499.1 - 0.03 13.6 0.0 1.4 8.2 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5614) Pex14_N PF04695.13 KZN88499.1 - 0.84 10.3 5.5 1.9 9.1 5.5 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Syntaxin-18_N PF10496.9 KZN88499.1 - 3.8 7.8 6.7 0.82 10.0 0.7 2.8 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus NAD_binding_10 PF13460.6 KZN88500.1 - 9.2e-18 64.8 0.0 1.5e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KZN88500.1 - 9.8e-15 54.7 0.0 1.4e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Shikimate_DH PF01488.20 KZN88500.1 - 0.0092 16.0 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 KZN88500.1 - 0.044 13.2 0.0 0.35 10.3 0.0 2.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Zn_clus PF00172.18 KZN88501.1 - 1.6e-07 31.3 13.3 2.7e-07 30.6 13.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN88501.1 - 2.2e-06 26.9 0.2 3e-06 26.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Lung_7-TM_R PF06814.13 KZN88502.1 - 7.7e-68 228.9 16.2 9.2e-68 228.6 16.2 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor CTU2 PF10288.9 KZN88503.1 - 1.8e-10 41.1 2.2 6.9e-08 32.7 0.0 3.0 2 1 1 3 3 3 2 Cytoplasmic tRNA 2-thiolation protein 2 FYVE PF01363.21 KZN88503.1 - 0.087 13.0 2.1 0.73 10.0 0.1 2.3 2 0 0 2 2 2 0 FYVE zinc finger DUF4112 PF13430.6 KZN88504.1 - 1.7e-34 118.2 0.4 2.2e-34 117.8 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DCP2 PF05026.13 KZN88505.1 - 8.3e-31 106.2 1.9 1.6e-30 105.3 1.9 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 KZN88505.1 - 7.8e-19 68.0 0.1 1.4e-18 67.2 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain GCV_T PF01571.21 KZN88506.1 - 0.00057 19.3 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DnaJ PF00226.31 KZN88507.1 - 1.1e-19 70.3 2.0 2e-19 69.5 0.9 2.0 2 0 0 2 2 2 1 DnaJ domain Presenilin PF01080.17 KZN88507.1 - 7.3 5.2 5.3 13 4.5 5.3 1.4 1 0 0 1 1 1 0 Presenilin Mei4 PF13971.6 KZN88508.1 - 0.0055 16.3 3.8 0.015 14.8 3.2 2.1 1 1 0 1 1 1 1 Meiosis-specific protein Mei4 GAT PF03127.14 KZN88508.1 - 7.8 6.9 7.3 14 6.0 0.1 3.9 3 1 1 4 4 4 0 GAT domain Amidohydro_2 PF04909.14 KZN88509.1 - 9.8e-27 94.5 0.0 2e-26 93.5 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 KZN88509.1 - 0.012 15.0 0.0 0.026 13.9 0.0 1.6 2 0 0 2 2 2 0 TatD related DNase EthD PF07110.11 KZN88510.1 - 0.025 15.7 0.0 0.035 15.3 0.0 1.2 1 0 0 1 1 1 0 EthD domain DIOX_N PF14226.6 KZN88512.1 - 1.4e-25 90.3 0.0 3e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KZN88512.1 - 2.2e-17 63.4 0.0 4e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.25 KZN88513.1 - 3.7e-35 121.2 0.2 1e-34 119.7 0.2 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN88513.1 - 1.1e-31 110.3 0.1 2.5e-30 105.7 0.1 2.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN88513.1 - 6e-08 32.8 0.9 1.2e-07 31.8 0.1 1.8 3 0 0 3 3 3 1 KR domain Polysacc_synt_2 PF02719.15 KZN88513.1 - 0.00048 19.3 0.2 0.00087 18.5 0.2 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KZN88513.1 - 0.01 14.9 0.3 0.022 13.7 0.1 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 KZN88513.1 - 0.03 14.6 0.2 0.054 13.7 0.2 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF1776 PF08643.10 KZN88513.1 - 0.039 13.3 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) GFO_IDH_MocA PF01408.22 KZN88514.1 - 2.7e-18 66.9 0.1 4.8e-18 66.1 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KZN88514.1 - 0.00019 21.4 0.0 0.00042 20.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Fungal_trans_2 PF11951.8 KZN88515.1 - 0.0021 16.9 0.3 0.0042 16.0 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain KRAB PF01352.27 KZN88515.1 - 0.64 9.7 2.9 0.74 9.5 1.2 2.0 2 0 0 2 2 2 0 KRAB box Ferritin_2 PF13668.6 KZN88518.1 - 1.2e-16 61.2 0.1 1.8e-16 60.6 0.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain DUF3658 PF12395.8 KZN88518.1 - 0.028 14.3 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function Rubrerythrin PF02915.17 KZN88518.1 - 0.052 14.0 0.0 0.15 12.4 0.0 1.7 1 1 0 1 1 1 0 Rubrerythrin AMP-binding PF00501.28 KZN88520.1 - 2.2e-69 234.1 0.0 3.1e-69 233.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KZN88520.1 - 4e-15 56.6 0.0 9.5e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SdpI PF13630.6 KZN88521.1 - 0.053 13.6 0.4 0.053 13.6 0.4 2.8 2 1 1 3 3 3 0 SdpI/YhfL protein family GpcrRhopsn4 PF10192.9 KZN88521.1 - 2.6 7.4 8.7 0.18 11.2 3.5 1.6 2 0 0 2 2 2 0 Rhodopsin-like GPCR transmembrane domain CcmF_C PF16327.5 KZN88521.1 - 4.7 6.4 13.1 0.14 11.4 5.9 1.8 1 1 1 2 2 2 0 Cytochrome c-type biogenesis protein CcmF C-terminal Syndecan PF01034.20 KZN88521.1 - 7.2 6.6 6.6 1.2 9.1 0.3 2.5 2 0 0 2 2 2 0 Syndecan domain Response_reg PF00072.24 KZN88522.1 - 2.1e-23 82.6 0.4 4.9e-23 81.4 0.4 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KZN88522.1 - 1.4e-16 61.0 0.0 4.1e-16 59.5 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KZN88522.1 - 1.4e-09 37.8 1.2 2.7e-09 36.9 0.2 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 KZN88522.1 - 0.013 15.8 0.0 0.034 14.4 0.0 1.8 1 0 0 1 1 1 0 GAF domain GAF_3 PF13492.6 KZN88522.1 - 0.098 13.0 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 GAF domain DUF1002 PF06207.11 KZN88522.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) CoA_transf_3 PF02515.17 KZN88523.1 - 8e-42 143.7 0.4 1.3e-40 139.7 0.1 2.1 2 0 0 2 2 2 2 CoA-transferase family III ABC_tran PF00005.27 KZN88524.1 - 1.4e-25 90.4 0.0 1.1e-13 51.9 0.0 3.7 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KZN88524.1 - 1.6e-09 38.1 2.9 5.9e-05 23.0 0.0 2.8 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KZN88524.1 - 5.7e-06 26.5 0.0 0.023 14.9 0.1 2.4 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KZN88524.1 - 0.0055 16.4 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KZN88524.1 - 0.0067 17.0 0.2 0.015 15.8 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KZN88524.1 - 0.0071 16.6 0.1 0.56 10.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 KZN88524.1 - 0.0099 15.6 0.1 17 5.1 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein SMC_N PF02463.19 KZN88524.1 - 0.016 14.6 0.0 0.69 9.3 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain NB-ARC PF00931.22 KZN88524.1 - 0.052 12.7 0.1 0.29 10.3 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_16 PF13191.6 KZN88524.1 - 0.11 12.8 0.0 0.3 11.5 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KZN88524.1 - 0.13 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 KZN88524.1 - 0.15 11.7 0.0 0.5 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Ploopntkinase1 PF18748.1 KZN88524.1 - 0.21 11.1 0.0 0.43 10.1 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 MscL PF01741.18 KZN88525.1 - 1.9e-17 63.7 0.1 2.7e-17 63.2 0.1 1.3 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL zf-ribbon_3 PF13248.6 KZN88525.1 - 0.00057 19.2 1.8 0.001 18.4 1.8 1.4 1 0 0 1 1 1 1 zinc-ribbon domain UPF0547 PF10571.9 KZN88525.1 - 0.0017 18.4 1.8 0.0035 17.4 1.8 1.4 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 zf-Di19 PF05605.12 KZN88525.1 - 0.028 14.7 0.5 0.052 13.9 0.5 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Rootletin PF15035.6 KZN88528.1 - 0.064 13.3 0.0 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion PLAC8 PF04749.17 KZN88529.1 - 4.4e-19 69.3 9.8 8.5e-19 68.4 9.8 1.5 1 0 0 1 1 1 1 PLAC8 family IPK PF03770.16 KZN88531.1 - 9.6e-58 195.3 0.0 1.6e-57 194.6 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.10 KZN88531.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 MFS_1 PF07690.16 KZN88532.1 - 1.2e-21 77.0 11.9 1.2e-21 77.0 11.9 1.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.13 KZN88532.1 - 6.6e-07 29.1 4.0 1.6e-06 27.8 2.7 2.0 2 0 0 2 2 2 1 Nodulin-like DUF1418 PF07214.12 KZN88532.1 - 2.6 7.9 4.4 7.8 6.4 0.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1418) ERCC4 PF02732.15 KZN88533.1 - 3.2e-34 118.4 0.0 6.5e-34 117.4 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain Glycos_transf_1 PF00534.20 KZN88533.1 - 6.3e-31 107.2 0.0 2.3e-29 102.1 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KZN88533.1 - 2.2e-16 60.3 0.2 9.7e-16 58.2 0.2 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KZN88533.1 - 4.6e-12 46.5 0.0 1.2e-11 45.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KZN88533.1 - 5e-07 30.3 2.3 5e-07 30.3 2.3 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KZN88533.1 - 0.0062 16.9 0.0 0.022 15.1 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 BIRC6 PF12356.8 KZN88534.1 - 0.13 11.6 0.1 0.32 10.4 0.1 1.5 1 1 0 1 1 1 0 Baculoviral IAP repeat-containing protein 6 DUF4133 PF13571.6 KZN88534.1 - 0.13 12.6 1.0 1.5 9.2 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) Kinesin PF00225.23 KZN88535.1 - 1e-91 307.3 0.2 1e-91 307.3 0.2 3.2 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KZN88535.1 - 1.4e-21 77.0 0.0 7.3e-17 61.7 0.0 3.0 1 1 1 2 2 2 2 Microtubule binding DUF641 PF04859.12 KZN88535.1 - 0.0045 17.3 3.9 0.0045 17.3 3.9 11.0 4 2 7 11 11 11 1 Plant protein of unknown function (DUF641) Cu-oxidase_2 PF07731.14 KZN88536.1 - 1.1e-47 161.2 5.0 1.3e-41 141.5 0.2 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KZN88536.1 - 7.5e-41 138.9 6.7 4.2e-39 133.2 1.4 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KZN88536.1 - 3.4e-35 121.5 1.2 3e-32 111.9 0.4 3.3 3 0 0 3 3 3 1 Multicopper oxidase Cupredoxin_1 PF13473.6 KZN88536.1 - 0.13 12.4 0.0 32 4.7 0.0 3.2 4 0 0 4 4 4 0 Cupredoxin-like domain FTR1 PF03239.14 KZN88537.1 - 2e-85 286.6 4.8 2.4e-85 286.4 4.8 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family LptF_LptG PF03739.14 KZN88537.1 - 0.8 8.5 6.1 0.098 11.5 1.5 1.8 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG NAD_binding_6 PF08030.12 KZN88538.1 - 5.2e-24 85.1 0.0 6.8e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KZN88538.1 - 7.1e-10 39.0 0.0 2.2e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KZN88538.1 - 8.2e-05 22.7 4.3 8.2e-05 22.7 4.3 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component APOBEC4_like PF18774.1 KZN88538.1 - 0.034 14.1 0.1 3.7 7.5 0.0 2.3 2 0 0 2 2 2 0 APOBEC4-like -AID/APOBEC-deaminase Pkr1 PF08636.10 KZN88538.1 - 1.3 9.2 6.3 18 5.6 2.9 2.5 2 0 0 2 2 2 0 ER protein Pkr1 CRAL_TRIO PF00650.20 KZN88539.1 - 2.4e-39 134.6 0.0 3.3e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KZN88539.1 - 1.2e-16 60.6 0.1 2.3e-16 59.7 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain HrpB_C PF08482.10 KZN88539.1 - 0.02 15.3 0.0 0.076 13.4 0.0 2.0 2 0 0 2 2 2 0 ATP-dependent helicase C-terminal CRAL_TRIO_2 PF13716.6 KZN88539.1 - 0.022 14.9 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Acetyltransf_16 PF05301.11 KZN88539.1 - 0.051 13.3 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 Pol_alpha_B_N PF08418.10 KZN88540.1 - 1.7e-80 270.6 0.1 2.2e-80 270.2 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 KZN88540.1 - 8e-36 123.4 0.0 1.2e-35 122.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Apc13p PF05839.11 KZN88541.1 - 3.5e-19 68.8 0.1 2e-14 53.5 0.0 2.2 2 0 0 2 2 2 2 Apc13p protein APH PF01636.23 KZN88542.1 - 9.8e-10 38.7 0.6 1.7e-09 38.0 0.5 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN88542.1 - 0.0016 18.1 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KZN88542.1 - 0.018 14.4 0.0 0.48 9.8 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain EcKinase PF02958.20 KZN88542.1 - 0.11 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Kdo PF06293.14 KZN88542.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IF-2B PF01008.17 KZN88543.1 - 1.2e-74 251.1 0.0 1.5e-74 250.7 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Kinesin PF00225.23 KZN88544.1 - 1e-112 376.4 0.0 1.5e-112 375.8 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KZN88544.1 - 5.4e-27 94.6 0.0 1.6e-26 93.0 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding Spc7 PF08317.11 KZN88544.1 - 0.0024 16.8 9.4 0.0042 16.0 9.4 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein RE_HindIII PF09518.10 KZN88544.1 - 0.1 11.8 5.5 0.17 11.1 5.5 1.2 1 0 0 1 1 1 0 HindIII restriction endonuclease DUF87 PF01935.17 KZN88544.1 - 0.37 10.8 4.7 0.81 9.7 0.0 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain HlyD_2 PF12700.7 KZN88544.1 - 0.82 8.3 4.7 0.71 8.5 3.5 1.4 2 0 0 2 2 2 0 HlyD family secretion protein DUF5094 PF17015.5 KZN88544.1 - 3.7 7.6 7.6 10 6.2 7.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) Peptidase_M32 PF02074.15 KZN88544.1 - 7 5.3 11.8 2.7 6.7 7.8 1.9 2 0 0 2 2 2 0 Carboxypeptidase Taq (M32) metallopeptidase Extensin_2 PF04554.13 KZN88545.1 - 0.012 15.6 2.1 0.029 14.5 2.1 1.6 1 0 0 1 1 1 0 Extensin-like region DUF1275 PF06912.11 KZN88546.1 - 6.7e-47 159.9 14.3 7.7e-47 159.7 14.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF1422 PF07226.11 KZN88546.1 - 0.016 15.3 2.0 0.22 11.5 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) Macro_2 PF14519.6 KZN88548.1 - 0.012 14.9 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Macro-like domain NKAP PF15692.5 KZN88548.1 - 0.12 13.2 0.7 0.93 10.3 0.0 2.2 2 0 0 2 2 2 0 NF-kappa-B-activating protein DUF5076 PF16826.5 KZN88548.1 - 0.12 12.3 0.0 0.36 10.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5076) Ion_trans_2 PF07885.16 KZN88549.1 - 4.1e-29 100.4 19.3 6.7e-17 61.2 5.9 3.2 3 1 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KZN88549.1 - 0.008 15.4 0.2 0.008 15.4 0.2 3.4 3 0 0 3 3 3 3 Ion transport protein Fungal_trans_2 PF11951.8 KZN88551.1 - 6.4e-51 173.3 0.2 1.2e-50 172.5 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN88551.1 - 2.4e-05 24.4 5.9 4.9e-05 23.4 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mannosyl_trans3 PF11051.8 KZN88552.1 - 6.6e-57 193.0 0.0 2.2e-35 122.3 0.0 2.1 1 1 1 2 2 2 2 Mannosyltransferase putative CMD PF02627.20 KZN88554.1 - 0.084 12.9 0.0 1.7 8.8 0.0 2.3 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family BCIP PF13862.6 KZN88555.1 - 1.6e-74 250.2 0.1 2.1e-74 249.8 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein WD40 PF00400.32 KZN88557.1 - 2.6e-28 97.7 12.6 8.8e-06 26.4 1.3 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 KZN88557.1 - 2.3e-08 33.1 0.7 0.076 11.6 0.1 4.8 3 1 2 5 5 5 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KZN88557.1 - 1.5e-05 25.2 0.1 0.19 12.0 0.0 4.2 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF5046 PF16465.5 KZN88557.1 - 0.087 12.3 0.2 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5046) Sad1_UNC PF07738.13 KZN88558.1 - 3.8e-11 43.1 0.0 6.3e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal SRR1 PF07985.12 KZN88559.1 - 5.6e-12 45.5 0.0 9.4e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 SRR1 SRR1 PF07985.12 KZN88560.1 - 7.7e-09 35.5 0.0 1.5e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 SRR1 CBS PF00571.28 KZN88562.1 - 1.9e-24 85.8 5.1 3.8e-09 36.9 0.1 4.3 4 0 0 4 4 4 4 CBS domain HTH_9 PF08221.11 KZN88562.1 - 0.075 13.1 0.9 4.8 7.4 0.0 3.6 4 0 0 4 4 4 0 RNA polymerase III subunit RPC82 helix-turn-helix domain RhoGAP PF00620.27 KZN88563.1 - 0.0076 16.1 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Sugar_tr PF00083.24 KZN88564.1 - 8.3e-110 367.7 12.2 9.4e-110 367.6 12.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN88564.1 - 6.3e-23 81.3 20.5 6.3e-23 81.3 20.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sulfatase PF00884.23 KZN88565.1 - 6.4e-71 239.3 0.0 8.1e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 KZN88565.1 - 0.068 13.4 0.0 0.16 12.3 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4976) DUF4994 PF16385.5 KZN88565.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function APH PF01636.23 KZN88566.1 - 1.3e-05 25.3 0.9 5.9e-05 23.1 0.9 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 KZN88566.1 - 0.089 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase Fungal_trans_2 PF11951.8 KZN88567.1 - 3e-13 49.4 0.2 1.1e-12 47.5 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN88567.1 - 1e-09 38.3 6.8 2.1e-09 37.4 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FPN1 PF06963.12 KZN88568.1 - 3.9e-147 490.3 26.3 4.6e-147 490.1 26.3 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Anophelin PF10731.9 KZN88568.1 - 0.084 12.7 0.2 0.22 11.4 0.2 1.6 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito ECH_2 PF16113.5 KZN88569.1 - 7.6e-129 430.0 0.0 9.9e-129 429.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KZN88569.1 - 3.1e-24 85.6 0.0 8.2e-24 84.3 0.0 1.6 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Ribosomal_L4 PF00573.22 KZN88570.1 - 3e-45 154.3 0.0 4.3e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family CENP-T_C PF15511.6 KZN88570.1 - 0.16 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold PBP PF01161.20 KZN88571.1 - 1.2e-09 38.6 0.0 1.9e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Peptidase_S26 PF10502.9 KZN88572.1 - 1.6e-06 27.9 0.0 0.00081 19.2 0.0 2.3 1 1 0 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 KZN88572.1 - 0.00017 21.4 0.1 0.00036 20.4 0.1 1.5 1 0 0 1 1 1 1 Peptidase S24-like DUF1264 PF06884.11 KZN88573.1 - 4e-78 260.9 0.0 4.7e-78 260.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) TMEM240 PF15207.6 KZN88573.1 - 0.14 11.8 0.2 0.23 11.2 0.2 1.2 1 0 0 1 1 1 0 TMEM240 family Acetyltransf_3 PF13302.7 KZN88575.1 - 1.9e-05 25.4 0.0 2.6e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KZN88575.1 - 0.0025 18.0 0.0 0.0073 16.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KZN88575.1 - 0.003 17.8 0.0 0.0042 17.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family adh_short PF00106.25 KZN88577.1 - 3.1e-11 43.1 0.0 1.7e-05 24.4 0.0 2.7 2 1 0 2 2 2 2 short chain dehydrogenase AP_endonuc_2 PF01261.24 KZN88578.1 - 0.00094 18.7 0.0 0.0051 16.3 0.0 2.1 1 1 1 2 2 2 1 Xylose isomerase-like TIM barrel ADH_N PF08240.12 KZN88579.1 - 4.7e-25 87.6 0.1 1.2e-24 86.2 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN88579.1 - 3.6e-08 33.4 0.1 7.4e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KZN88579.1 - 5.2e-06 26.3 0.2 1.3e-05 25.0 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 KZN88579.1 - 8.2e-05 22.2 0.0 0.0011 18.6 0.0 2.1 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KZN88579.1 - 0.002 17.4 0.3 0.0035 16.7 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KZN88579.1 - 0.003 16.3 0.2 0.0079 14.9 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KZN88579.1 - 0.014 14.5 0.5 0.033 13.3 0.2 1.5 1 1 1 2 2 2 0 FAD binding domain TrkA_N PF02254.18 KZN88579.1 - 0.018 15.3 0.0 0.038 14.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.14 KZN88579.1 - 0.03 13.5 0.1 0.097 11.9 0.1 1.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_25 PF13649.6 KZN88579.1 - 0.034 14.9 0.0 0.1 13.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain DAO PF01266.24 KZN88579.1 - 0.038 13.6 0.1 0.071 12.7 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 KZN88579.1 - 0.097 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF5357 PF17310.2 KZN88580.1 - 0.029 13.0 0.4 0.053 12.1 0.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5357) Pkinase PF00069.25 KZN88581.1 - 5.8e-25 88.1 0.0 1e-24 87.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN88581.1 - 1.8e-07 30.8 0.0 3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KZN88581.1 - 0.074 13.0 0.4 0.16 11.9 0.4 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family UPF0688 PF15772.5 KZN88582.1 - 0.12 12.7 2.6 0.2 11.9 2.6 1.3 1 0 0 1 1 1 0 UPF0688 family Las1 PF04031.13 KZN88583.1 - 5.6e-46 156.4 0.1 9.4e-46 155.7 0.1 1.4 1 0 0 1 1 1 1 Las1-like HAGH_C PF16123.5 KZN88583.1 - 1.1e-19 70.7 0.2 2.1e-19 69.8 0.2 1.5 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KZN88583.1 - 4.6e-19 69.2 0.3 3.5e-18 66.3 0.3 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KZN88583.1 - 0.0037 16.8 0.5 0.021 14.4 0.5 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.20 KZN88583.1 - 0.07 12.6 0.3 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family NAD_kinase PF01513.21 KZN88584.1 - 3.7e-72 243.0 0.0 5.7e-72 242.4 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase L_biotic_typeA PF04604.13 KZN88584.1 - 0.074 12.9 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Type-A lantibiotic TRAPP PF04051.16 KZN88585.1 - 5.5e-40 136.4 0.0 7.1e-40 136.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component MFAP1 PF06991.11 KZN88586.1 - 8.7e-68 228.4 30.2 8.7e-68 228.4 30.2 3.4 3 1 1 4 4 4 1 Microfibril-associated/Pre-mRNA processing Rep_fac-A_3 PF08661.11 KZN88587.1 - 1.1e-25 89.9 0.0 1.3e-25 89.7 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Ten1 PF12658.7 KZN88587.1 - 0.002 18.1 0.1 0.019 14.9 0.1 2.0 1 1 0 1 1 1 1 Telomere capping, CST complex subunit GATA PF00320.27 KZN88588.1 - 0.0016 18.0 3.5 0.031 13.9 1.0 2.7 2 0 0 2 2 2 2 GATA zinc finger LSM PF01423.22 KZN88589.1 - 3.4e-19 68.3 0.1 4.6e-19 67.9 0.1 1.2 1 0 0 1 1 1 1 LSM domain Dak1 PF02733.17 KZN88590.1 - 4e-102 341.3 0.1 5.6e-102 340.8 0.1 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KZN88590.1 - 2.6e-45 154.4 0.2 4.3e-45 153.7 0.2 1.4 1 0 0 1 1 1 1 DAK2 domain Cullin PF00888.22 KZN88591.1 - 4e-183 610.4 0.1 4.9e-183 610.1 0.1 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KZN88591.1 - 3e-24 84.8 0.4 9.9e-24 83.2 0.4 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain HbrB PF08539.11 KZN88591.1 - 0.052 13.5 0.0 0.27 11.2 0.0 2.3 1 1 1 2 2 2 0 HbrB-like Peptidase_C48 PF02902.19 KZN88592.1 - 5e-15 55.9 0.3 3.8e-14 53.1 0.3 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Zn_clus PF00172.18 KZN88593.1 - 1.5e-05 25.0 3.1 6e-05 23.1 3.1 2.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MVP_shoulder PF11978.8 KZN88593.1 - 0.046 13.7 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Shoulder domain zf-C3H1 PF10650.9 KZN88593.1 - 0.075 12.8 0.1 0.21 11.3 0.1 1.8 1 0 0 1 1 1 0 Putative zinc-finger domain RhoGEF PF00621.20 KZN88595.1 - 9.5e-36 123.7 0.0 1.8e-35 122.8 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain Telomerase_RBD PF12009.8 KZN88596.1 - 5e-49 165.8 0.8 1.2e-48 164.6 0.8 1.7 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 KZN88596.1 - 1.9e-13 50.5 0.0 4.9e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RabGAP-TBC PF00566.18 KZN88597.1 - 1e-28 100.5 0.1 2.5e-28 99.2 0.0 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain SBE2 PF17076.5 KZN88597.1 - 1e-06 27.4 0.6 1.6e-06 26.7 0.6 1.3 1 0 0 1 1 1 1 SBE2, cell-wall formation NINJA_B PF16136.5 KZN88597.1 - 2.3 8.6 9.9 0.47 10.8 5.4 2.2 2 0 0 2 2 2 0 Putative nuclear localisation signal Cation_ATPase_C PF00689.21 KZN88598.1 - 2.6e-42 144.6 4.0 2.6e-42 144.6 4.0 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KZN88598.1 - 6.8e-38 130.0 2.2 6.8e-38 130.0 2.2 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KZN88598.1 - 2.3e-22 80.4 0.0 1.5e-10 41.8 0.0 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KZN88598.1 - 1.2e-20 73.3 0.0 2.3e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KZN88598.1 - 3.1e-10 39.6 0.0 8.1e-10 38.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KZN88598.1 - 0.00011 22.1 0.2 0.00039 20.3 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Colicin_V PF02674.16 KZN88598.1 - 0.012 15.5 2.6 0.012 15.5 2.6 2.9 3 0 0 3 3 3 0 Colicin V production protein HAD PF12710.7 KZN88598.1 - 0.018 15.4 0.0 0.82 10.0 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase FtsK_4TM PF13491.6 KZN88598.1 - 0.33 10.6 10.0 0.7 9.6 1.6 3.4 3 0 0 3 3 3 0 4TM region of DNA translocase FtsK/SpoIIIE DUF2157 PF09925.9 KZN88598.1 - 0.5 10.2 4.3 11 5.7 0.6 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) Virul_fac_BrkB PF03631.15 KZN88598.1 - 9.9 5.7 17.6 0.011 15.4 1.8 3.3 3 1 0 3 3 3 0 Virulence factor BrkB Pkinase PF00069.25 KZN88599.1 - 8.5e-25 87.6 0.0 4.9e-18 65.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KZN88599.1 - 9.3e-15 54.6 0.0 1.9e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase adh_short_C2 PF13561.6 KZN88600.1 - 5.1e-40 137.5 0.3 1.4e-39 136.0 0.3 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN88600.1 - 8e-40 136.4 0.9 1.6e-39 135.4 0.9 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN88600.1 - 1.7e-09 37.8 0.7 3.2e-09 37.0 0.3 1.6 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KZN88600.1 - 0.00092 18.7 0.4 0.0033 16.9 0.1 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 KZN88600.1 - 0.0027 17.1 0.1 0.0045 16.4 0.1 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Glu_dehyd_C PF16912.5 KZN88600.1 - 0.0039 16.7 0.2 0.0096 15.4 0.0 1.7 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 KZN88600.1 - 0.075 13.1 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ADH_zinc_N PF00107.26 KZN88600.1 - 0.085 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Epimerase PF01370.21 KZN88600.1 - 0.14 11.6 0.6 0.73 9.2 0.3 2.1 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family ADH_N_2 PF16884.5 KZN88601.1 - 9.1e-25 86.7 0.0 2.1e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KZN88601.1 - 1.3e-18 67.2 0.1 2.6e-18 66.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KZN88601.1 - 2.5e-08 35.0 0.0 4.9e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3806 PF12713.7 KZN88601.1 - 0.066 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3806) Abhydrolase_6 PF12697.7 KZN88603.1 - 0.01 16.4 1.2 0.01 16.4 1.2 2.3 2 2 0 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KZN88603.1 - 0.02 14.2 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LCAT PF02450.15 KZN88603.1 - 0.025 13.8 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF676 PF05057.14 KZN88603.1 - 0.079 12.5 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ribosomal_S28e PF01200.18 KZN88604.1 - 8.4e-32 109.0 1.7 9.3e-32 108.8 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e MutS_V PF00488.21 KZN88605.1 - 2.1e-74 249.7 0.1 4.4e-74 248.6 0.1 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KZN88605.1 - 2.9e-35 122.2 0.6 7.2e-35 121.0 0.6 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KZN88605.1 - 3e-29 101.6 0.0 8.5e-29 100.1 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KZN88605.1 - 3.4e-08 33.8 0.0 1.2e-07 32.1 0.0 2.0 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 KZN88605.1 - 0.00087 19.6 0.0 0.0033 17.7 0.0 2.0 1 0 0 1 1 1 1 MutS family domain IV Prenyltrans PF00432.21 KZN88606.1 - 2.2e-53 177.6 7.4 2.1e-11 43.4 0.1 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KZN88606.1 - 0.00012 21.3 0.1 0.01 15.0 0.1 2.8 1 1 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KZN88606.1 - 0.00061 19.0 0.0 0.17 11.0 0.0 3.3 3 1 1 4 4 4 2 Squalene-hopene cyclase N-terminal domain RhoGAP PF00620.27 KZN88607.1 - 1.2e-27 96.6 0.0 1.9e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain RRS1 PF04939.12 KZN88608.1 - 7.8e-58 194.9 3.3 9.8e-58 194.6 3.3 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) DAP3 PF10236.9 KZN88609.1 - 1.7e-99 332.9 0.0 2.1e-99 332.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 T2SSE PF00437.20 KZN88609.1 - 0.0069 15.5 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein Aldo_ket_red PF00248.21 KZN88610.1 - 3.1e-65 220.3 0.0 3.5e-65 220.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Claudin_3 PF06653.11 KZN88610.1 - 0.021 14.8 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like CAMP_factor PF07373.11 KZN88610.1 - 0.09 12.4 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 CAMP factor (Cfa) Arylsulfotran_2 PF14269.6 KZN88611.1 - 3.1e-44 151.6 0.1 4.4e-44 151.0 0.1 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KZN88611.1 - 1.6e-12 47.1 1.6 5.7e-11 41.9 1.6 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DUF3405 PF11885.8 KZN88612.1 - 1.2e-163 545.4 8.7 4.2e-161 537.1 8.7 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) KRBA1 PF15287.6 KZN88612.1 - 0.042 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 KRBA1 family repeat SET PF00856.28 KZN88613.1 - 2.8e-09 37.6 0.0 8.4e-08 32.8 0.0 2.4 1 1 0 1 1 1 1 SET domain SAP PF02037.27 KZN88613.1 - 1.7e-06 27.6 0.0 3.4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 SAP domain TPR_16 PF13432.6 KZN88613.1 - 0.0008 20.0 0.0 0.0018 18.9 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 KZN88613.1 - 0.0052 17.1 0.1 0.014 15.7 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KZN88613.1 - 0.012 15.4 0.2 0.97 9.4 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KZN88613.1 - 0.022 14.4 0.1 0.051 13.3 0.1 1.6 1 0 0 1 1 1 0 TPR repeat TPR_2 PF07719.17 KZN88613.1 - 0.064 13.4 0.3 1.5 9.2 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat RecC_C PF17946.1 KZN88615.1 - 0.042 13.6 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 RecC C-terminal domain TRAP_alpha PF03896.16 KZN88615.1 - 0.061 12.5 0.9 0.095 11.9 0.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pox_Ag35 PF03286.14 KZN88615.1 - 0.32 10.8 3.7 0.71 9.6 3.7 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.12 KZN88615.1 - 0.94 7.6 8.3 1.3 7.1 8.3 1.1 1 0 0 1 1 1 0 Nop14-like family Astro_capsid_p PF12226.8 KZN88615.1 - 8 5.5 7.3 13 4.8 7.3 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein NRN1 PF15056.6 KZN88616.1 - 0.43 10.7 3.7 0.18 11.9 0.6 2.0 2 0 0 2 2 2 0 Neuritin protein family DUF4219 PF13961.6 KZN88616.1 - 0.45 10.2 4.8 0.28 10.9 2.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) ADH_N PF08240.12 KZN88617.1 - 8.2e-26 90.0 0.7 1.3e-25 89.3 0.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN88617.1 - 3.4e-21 75.6 0.2 5.1e-21 75.0 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KZN88617.1 - 0.0062 17.6 0.1 0.011 16.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KZN88617.1 - 0.025 14.5 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase PI3_PI4_kinase PF00454.27 KZN88619.1 - 1.2e-52 179.2 0.2 8.1e-52 176.5 0.0 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 KZN88619.1 - 4e-47 160.1 2.0 1.6e-46 158.1 2.0 2.2 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 KZN88619.1 - 2.4e-09 36.9 0.1 5.6e-09 35.7 0.1 1.7 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 KZN88619.1 - 1.9e-05 24.0 2.7 4.5e-05 22.8 2.7 1.6 1 0 0 1 1 1 1 FAT domain Nup192 PF11894.8 KZN88620.1 - 0 1448.2 6.2 0 1448.0 6.2 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 DCB PF16213.5 KZN88620.1 - 0.06 13.0 2.9 0.78 9.4 1.3 3.1 2 1 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 SLX9 PF15341.6 KZN88621.1 - 0.024 15.0 2.0 11 6.4 0.1 3.2 1 1 1 2 2 2 0 Ribosome biogenesis protein SLX9 Cyclin PF08613.11 KZN88623.1 - 9.1e-37 126.9 10.8 3.4e-24 86.0 0.6 3.2 3 1 0 3 3 3 2 Cyclin Proteasome PF00227.26 KZN88624.1 - 2.9e-43 147.6 0.0 3.2e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Hydrolase_4 PF12146.8 KZN88625.1 - 8.6e-16 57.9 0.0 2.3e-10 40.2 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KZN88625.1 - 1.9e-10 40.9 0.0 2.2e-06 27.5 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KZN88625.1 - 5.6e-06 27.1 0.1 8.1e-05 23.3 0.0 2.2 2 1 1 3 3 3 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KZN88625.1 - 1.9e-05 24.3 0.0 0.00012 21.7 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF818 PF05677.12 KZN88625.1 - 0.0002 20.5 0.0 0.00027 20.0 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) AXE1 PF05448.12 KZN88625.1 - 0.00022 20.0 0.0 0.27 9.9 0.0 2.5 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 KZN88625.1 - 0.00045 20.2 0.0 0.064 13.2 0.0 2.4 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 KZN88625.1 - 0.00055 19.7 0.0 0.0025 17.5 0.0 2.1 2 1 0 2 2 2 1 Serine hydrolase (FSH1) DLH PF01738.18 KZN88625.1 - 0.0087 15.6 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Thioesterase PF00975.20 KZN88625.1 - 0.026 14.6 0.0 0.041 14.0 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 KZN88625.1 - 0.046 13.4 0.1 1.1 8.9 0.0 2.3 1 1 0 1 1 1 0 PGAP1-like protein Esterase PF00756.20 KZN88625.1 - 0.099 12.3 0.0 1.5 8.4 0.0 2.1 2 0 0 2 2 2 0 Putative esterase ATP11 PF06644.11 KZN88626.1 - 5.5e-98 328.1 0.0 6.4e-98 327.9 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Cupin_7 PF12973.7 KZN88627.1 - 1.8e-07 31.0 0.0 2.2e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 ChrR Cupin-like domain R3H PF01424.22 KZN88628.1 - 9.9e-11 41.5 0.2 3.3e-10 39.8 0.0 1.9 2 0 0 2 2 2 1 R3H domain zf-NF-X1 PF01422.17 KZN88628.1 - 4.1e-05 23.5 13.1 4.1e-05 23.5 13.1 14.0 14 0 0 14 14 14 6 NF-X1 type zinc finger zf-LYAR PF08790.11 KZN88629.1 - 1.5e-14 53.5 4.1 1.5e-14 53.5 4.1 1.9 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger Eapp_C PF10238.9 KZN88629.1 - 0.057 13.5 0.1 0.057 13.5 0.1 2.9 3 0 0 3 3 3 0 E2F-associated phosphoprotein Evr1_Alr PF04777.13 KZN88630.1 - 4e-19 68.9 1.0 3e-11 43.7 0.0 2.2 2 0 0 2 2 2 2 Erv1 / Alr family Glyco_hydro_92 PF07971.12 KZN88631.1 - 1.1e-149 499.3 0.2 1.3e-149 499.1 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KZN88631.1 - 1.3e-64 218.4 0.7 1.9e-64 217.8 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain CEP63 PF17045.5 KZN88632.1 - 0.00017 21.6 0.5 0.00019 21.4 0.5 1.1 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa GPW_gp25 PF04965.14 KZN88632.1 - 0.051 13.3 0.1 0.057 13.2 0.1 1.2 1 0 0 1 1 1 0 Gene 25-like lysozyme UPF0242 PF06785.11 KZN88632.1 - 0.061 13.4 0.2 0.082 13.0 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Aldo_ket_red PF00248.21 KZN88634.1 - 8.3e-63 212.3 0.0 1e-62 212.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PIN_6 PF17146.4 KZN88634.1 - 0.17 12.4 0.1 2 9.0 0.0 2.4 2 1 0 2 2 2 0 PIN domain of ribonuclease MFS_1 PF07690.16 KZN88635.1 - 1.4e-18 66.9 56.4 4.6e-14 52.1 32.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KZN88635.1 - 0.00085 17.9 7.7 0.0016 17.0 7.7 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) WTF PF03303.13 KZN88635.1 - 0.6 9.8 3.5 1.5 8.5 3.5 1.6 1 0 0 1 1 1 0 WTF protein MFS_1 PF07690.16 KZN88636.1 - 3.1e-50 171.1 36.0 3.1e-50 171.1 36.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN88636.1 - 1.1e-12 47.6 3.1 1.1e-12 47.6 3.1 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 KZN88636.1 - 3.2e-06 26.7 6.7 3.2e-06 26.7 6.7 2.5 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB MBOAT_2 PF13813.6 KZN88638.1 - 1.8e-19 69.8 1.9 7.3e-19 67.8 1.9 2.1 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family RBM39linker PF15519.6 KZN88639.1 - 0.12 13.4 0.1 0.31 12.2 0.0 1.7 1 1 1 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein UL42 PF17638.2 KZN88640.1 - 0.097 12.6 1.2 0.19 11.7 0.1 1.9 2 0 0 2 2 2 0 HCMV UL42 Fungal_trans_2 PF11951.8 KZN88641.1 - 3.7e-06 26.0 2.9 5.1e-05 22.3 1.9 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN88641.1 - 0.0012 18.9 4.1 0.0019 18.2 4.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain G_glu_transpept PF01019.21 KZN88642.1 - 7.9e-166 552.8 0.1 9.1e-166 552.6 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Git3 PF11710.8 KZN88644.1 - 1.8e-32 112.8 15.1 1.8e-32 112.8 15.1 1.7 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KZN88644.1 - 3.5e-14 52.6 0.0 1.1e-13 51.0 0.0 1.9 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 KZN88644.1 - 4.8e-05 22.8 10.7 4.8e-05 22.8 10.7 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 KZN88644.1 - 0.00059 19.1 17.8 0.00086 18.5 17.4 1.4 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor OapA_N PF08525.11 KZN88644.1 - 0.018 15.0 2.3 0.025 14.5 0.0 2.5 2 0 0 2 2 2 0 Opacity-associated protein A N-terminal motif Fungal_lectin PF07938.12 KZN88645.1 - 2.3e-158 526.3 4.4 2.6e-158 526.1 4.4 1.0 1 0 0 1 1 1 1 Fungal fucose-specific lectin Alkyl_sulf_dimr PF14863.6 KZN88645.1 - 0.057 13.9 0.1 0.58 10.6 0.0 2.2 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation Alpha-mann_mid PF09261.11 KZN88645.1 - 0.15 12.2 0.0 0.74 10.0 0.0 2.1 2 0 0 2 2 2 0 Alpha mannosidase middle domain Aldo_ket_red PF00248.21 KZN88646.1 - 1.9e-69 234.1 0.0 2.1e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Methyltransf_15 PF09445.10 KZN88646.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Fungal_trans_2 PF11951.8 KZN88647.1 - 2.4e-20 72.7 7.3 6.9e-10 38.3 1.5 2.1 1 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN88647.1 - 0.00027 21.0 11.6 0.00049 20.2 11.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.6 KZN88648.1 - 7.8e-45 153.5 42.9 1.7e-42 145.7 42.9 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN88648.1 - 1.3e-16 60.3 37.8 5.6e-15 54.9 37.8 2.0 1 1 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.21 KZN88648.1 - 0.0087 16.0 1.3 0.04 13.9 0.0 2.8 2 0 0 2 2 2 1 LPXTG cell wall anchor motif Amino_oxidase PF01593.24 KZN88649.1 - 1.9e-54 185.7 0.1 2.2e-54 185.4 0.1 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KZN88649.1 - 2.3e-14 53.4 0.1 4.3e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KZN88649.1 - 5.7e-10 39.3 0.0 1.7e-08 34.4 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KZN88649.1 - 4e-08 32.8 0.2 6.8e-08 32.0 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KZN88649.1 - 7.5e-07 28.8 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KZN88649.1 - 2.6e-06 26.8 0.3 4.1e-06 26.1 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KZN88649.1 - 2.6e-05 23.6 0.0 6.8e-05 22.2 0.0 1.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KZN88649.1 - 6.6e-05 21.8 0.0 0.00015 20.7 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KZN88649.1 - 8.6e-05 21.9 0.3 0.00013 21.3 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KZN88649.1 - 0.00011 21.5 0.0 0.00014 21.1 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KZN88649.1 - 0.00013 22.5 0.1 0.00033 21.2 0.0 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KZN88649.1 - 0.00074 18.7 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KZN88649.1 - 0.00078 19.5 0.1 0.32 11.0 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KZN88649.1 - 0.01 15.1 0.0 0.57 9.4 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.18 KZN88650.1 - 3.8e-25 88.4 0.2 8.3e-25 87.3 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN88650.1 - 7.8e-09 35.5 10.1 2e-08 34.2 10.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.27 KZN88651.1 - 3.6e-53 177.5 1.1 2.2e-18 66.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Acyl-CoA_dh_1 PF00441.24 KZN88652.1 - 4.2e-29 101.7 0.5 6e-29 101.2 0.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KZN88652.1 - 5.4e-22 77.8 0.1 9.2e-22 77.1 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KZN88652.1 - 2.2e-20 73.4 0.0 3.8e-19 69.4 0.0 2.8 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 KZN88652.1 - 0.021 14.5 0.6 0.065 12.9 0.3 1.9 2 1 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal FA_desaturase_2 PF03405.14 KZN88652.1 - 0.13 11.1 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Fatty acid desaturase DAGAT PF03982.13 KZN88652.1 - 0.18 10.7 0.1 0.28 10.0 0.1 1.2 1 0 0 1 1 1 0 Diacylglycerol acyltransferase CPSase_L_D2 PF02786.17 KZN88653.1 - 2.4e-69 233.1 0.1 4.2e-69 232.3 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KZN88653.1 - 5.5e-41 139.6 0.6 1.6e-40 138.1 0.1 2.0 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KZN88653.1 - 4.7e-31 107.1 0.0 9.6e-31 106.1 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp PF02222.22 KZN88653.1 - 2e-10 40.5 0.4 1.9e-09 37.4 0.1 2.5 1 1 1 2 2 2 1 ATP-grasp domain Biotin_lipoyl PF00364.22 KZN88653.1 - 3.6e-10 39.5 1.1 8.6e-10 38.3 1.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KZN88653.1 - 8.2e-10 38.6 0.0 2e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KZN88653.1 - 7.3e-06 26.1 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KZN88653.1 - 0.00015 21.4 0.0 0.0004 20.0 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 KZN88653.1 - 0.0074 15.9 0.1 0.017 14.7 0.1 1.7 1 0 0 1 1 1 1 ATP-grasp domain GCV_H PF01597.19 KZN88653.1 - 0.03 14.2 0.1 0.38 10.6 0.2 2.4 2 0 0 2 2 2 0 Glycine cleavage H-protein DUF3182 PF11379.8 KZN88653.1 - 0.092 11.7 0.1 0.25 10.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3182) ATPgrasp_ST PF14397.6 KZN88653.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp CytochromB561_N PF09786.9 KZN88653.1 - 0.16 10.9 2.1 0.28 10.1 2.1 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Carboxyl_trans PF01039.22 KZN88654.1 - 7.8e-115 384.3 0.0 9e-115 384.1 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain AMP-binding PF00501.28 KZN88655.1 - 3.5e-91 305.9 0.0 4.2e-91 305.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KZN88655.1 - 1.2e-12 48.6 0.0 4.9e-12 46.7 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ribosomal_L7Ae PF01248.26 KZN88655.1 - 0.056 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family HMGL-like PF00682.19 KZN88656.1 - 1.5e-45 155.8 0.0 2e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 HMGL-like ECH_1 PF00378.20 KZN88656.1 - 3.8e-37 127.9 0.0 5.5e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KZN88656.1 - 1.3e-21 77.5 0.0 1.9e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase FAD_binding_4 PF01565.23 KZN88657.1 - 4.4e-24 84.8 2.2 8.7e-24 83.8 2.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KZN88658.1 - 1.2e-09 38.1 0.1 1.6e-09 37.7 0.1 1.2 1 0 0 1 1 1 1 Berberine and berberine like Glyco_hydro_76 PF03663.14 KZN88659.1 - 3.8e-45 155.0 8.9 4.9e-45 154.6 8.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KZN88659.1 - 0.00012 21.3 0.2 0.012 14.7 0.0 2.4 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 BetaGal_dom2 PF10435.9 KZN88660.1 - 2.8e-38 131.5 0.0 4.4e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KZN88660.1 - 1.3e-14 53.5 0.2 2.8e-14 52.5 0.2 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 GST_N PF02798.20 KZN88661.1 - 2.2e-08 34.3 0.0 3.7e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KZN88661.1 - 1.3e-05 25.5 0.0 2.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KZN88661.1 - 8.2e-05 22.8 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KZN88661.1 - 0.00025 21.2 0.0 0.00043 20.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KZN88661.1 - 0.0013 18.8 0.0 0.0021 18.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KZN88661.1 - 0.03 14.4 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Lactamase_B PF00753.27 KZN88662.1 - 9.1e-15 55.2 0.1 1.5e-14 54.4 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily zf-CCCH_4 PF18044.1 KZN88663.1 - 0.00045 20.0 3.6 0.00045 20.0 3.6 4.0 5 0 0 5 5 5 1 CCCH-type zinc finger Torus PF16131.5 KZN88663.1 - 0.00085 20.0 1.0 0.00085 20.0 1.0 2.0 2 0 0 2 2 2 1 Torus domain zf-CCCH PF00642.24 KZN88663.1 - 0.0034 17.2 1.6 0.0034 17.2 1.6 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Dynactin_p22 PF07426.11 KZN88663.1 - 0.067 13.0 0.8 0.19 11.6 0.7 1.7 2 0 0 2 2 2 0 Dynactin subunit p22 ZapB PF06005.12 KZN88663.1 - 0.2 12.1 1.2 0.34 11.4 0.3 1.8 2 1 0 2 2 2 0 Cell division protein ZapB GrpB PF04229.14 KZN88663.1 - 0.21 11.8 0.3 0.42 10.8 0.3 1.4 1 0 0 1 1 1 0 GrpB protein KELK PF15796.5 KZN88663.1 - 0.25 11.8 2.9 0.46 11.0 2.9 1.4 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase SKA2 PF16740.5 KZN88663.1 - 0.26 11.1 2.9 0.22 11.3 0.4 2.1 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 zf_CCCH_4 PF18345.1 KZN88663.1 - 5.3 7.2 14.6 0.22 11.6 6.5 3.0 3 0 0 3 3 3 0 Zinc finger domain APH PF01636.23 KZN88664.1 - 3.6e-17 63.1 0.3 7.7e-17 62.0 0.3 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN88664.1 - 0.0005 19.7 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase NDUF_B5 PF09781.9 KZN88664.1 - 0.048 13.2 0.1 0.084 12.5 0.1 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit RIO1 PF01163.22 KZN88664.1 - 0.1 12.1 0.1 4.5 6.8 0.0 2.8 3 0 0 3 3 3 0 RIO1 family DUF4959 PF16323.5 KZN88664.1 - 0.13 12.6 0.0 0.83 10.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4959) RET_CLD1 PF17756.1 KZN88664.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 RET Cadherin like domain 1 F-box-like PF12937.7 KZN88665.1 - 5.5e-10 39.0 0.1 1.8e-09 37.3 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN88665.1 - 3e-05 23.8 0.0 0.00012 21.8 0.0 2.0 1 0 0 1 1 1 1 F-box domain Beta-lactamase PF00144.24 KZN88667.1 - 1.6e-57 195.2 0.0 2e-57 194.9 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Xan_ur_permease PF00860.20 KZN88668.1 - 1.3e-22 80.1 34.2 1.9e-21 76.2 31.8 2.5 2 1 0 2 2 2 1 Permease family MFS_1 PF07690.16 KZN88669.1 - 2.1e-35 122.3 45.2 2.1e-35 122.3 45.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN88669.1 - 7e-10 38.4 14.0 7e-10 38.4 14.0 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter DUF4690 PF15756.5 KZN88671.1 - 6.6e-06 26.7 5.7 6.6e-06 26.7 5.7 1.9 3 0 0 3 3 1 1 Small Novel Rich in Cartilage Podoplanin PF05808.11 KZN88671.1 - 1.6e-05 25.1 3.5 3.2e-05 24.1 3.5 1.4 1 0 0 1 1 1 1 Podoplanin Glycophorin_A PF01102.18 KZN88671.1 - 0.00012 22.3 1.2 0.00022 21.5 1.2 1.5 1 0 0 1 1 1 1 Glycophorin A TMEM154 PF15102.6 KZN88671.1 - 0.00041 20.3 1.1 0.00067 19.6 1.1 1.4 1 0 0 1 1 1 1 TMEM154 protein family RIFIN PF02009.16 KZN88671.1 - 0.007 16.3 0.0 0.0078 16.1 0.0 1.1 1 0 0 1 1 1 1 Rifin SKG6 PF08693.10 KZN88671.1 - 0.0071 15.7 3.8 0.018 14.5 3.8 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 KZN88671.1 - 0.03 14.1 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF4064 PF13273.6 KZN88671.1 - 0.033 14.5 2.2 0.061 13.6 2.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Amnionless PF14828.6 KZN88671.1 - 0.034 13.0 0.2 0.049 12.5 0.2 1.2 1 0 0 1 1 1 0 Amnionless AJAP1_PANP_C PF15298.6 KZN88671.1 - 0.069 13.3 4.1 0.12 12.6 4.1 1.4 1 0 0 1 1 1 0 AJAP1/PANP C-terminus DUF5305 PF17231.2 KZN88671.1 - 0.092 12.1 0.4 0.14 11.5 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) EphA2_TM PF14575.6 KZN88671.1 - 0.098 13.6 0.0 0.21 12.5 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4366 PF14283.6 KZN88671.1 - 0.11 12.5 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Stevor PF17410.2 KZN88671.1 - 0.16 11.5 0.1 0.23 11.0 0.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame TrbL PF04610.14 KZN88671.1 - 0.28 10.9 3.8 0.39 10.4 3.8 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Mid2 PF04478.12 KZN88671.1 - 0.42 10.4 7.6 0.87 9.4 4.9 2.3 1 1 1 2 2 2 0 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 KZN88671.1 - 0.58 10.0 5.6 1.3 8.9 5.6 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.20 KZN88671.1 - 1.6 8.7 6.0 0.42 10.6 2.3 1.8 2 0 0 2 2 2 0 Syndecan domain Shisa PF13908.6 KZN88671.1 - 1.8 8.8 8.7 8.1 6.6 0.4 2.2 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Gram_pos_anchor PF00746.21 KZN88671.1 - 2.1 8.4 5.0 2.5 8.1 2.9 2.1 1 1 1 2 2 2 0 LPXTG cell wall anchor motif MGC-24 PF05283.11 KZN88671.1 - 4.8 7.6 11.8 4.4 7.7 9.9 1.9 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Sugar_tr PF00083.24 KZN88674.1 - 5.5e-127 424.4 23.3 6.3e-127 424.2 23.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN88674.1 - 9.5e-25 87.3 36.8 2.9e-21 75.8 14.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4381 PF14316.6 KZN88674.1 - 0.095 12.9 0.0 0.51 10.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) ThiF PF00899.21 KZN88675.1 - 7.6e-60 202.3 0.0 1e-59 201.9 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KZN88675.1 - 9.4e-08 32.5 0.1 3.5e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 KZN88675.1 - 0.014 15.4 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KZN88675.1 - 0.054 13.9 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF4407 PF14362.6 KZN88675.1 - 0.26 10.6 1.8 0.38 10.1 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DPBB_1 PF03330.18 KZN88676.1 - 0.00011 22.4 0.1 0.00023 21.3 0.1 1.6 1 1 0 1 1 1 1 Lytic transglycolase Ntox17 PF15524.6 KZN88676.1 - 0.055 13.8 0.0 0.089 13.1 0.0 1.3 1 0 0 1 1 1 0 Novel toxin 17 adh_short_C2 PF13561.6 KZN88678.1 - 5.1e-56 189.8 0.0 6.5e-56 189.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN88678.1 - 6.1e-45 153.1 0.0 7.7e-45 152.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN88678.1 - 5e-13 49.3 0.0 7.1e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Abhydrolase_3 PF07859.13 KZN88679.1 - 1.3e-32 113.4 0.0 1.6e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KZN88679.1 - 4.9e-09 36.0 0.0 7.1e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KZN88679.1 - 1.3e-05 24.9 0.0 0.0062 16.1 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family BAAT_C PF08840.11 KZN88679.1 - 0.037 14.0 0.0 0.086 12.7 0.0 1.5 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal COesterase PF00135.28 KZN88679.1 - 0.1 11.5 0.0 0.39 9.5 0.0 1.8 1 1 0 1 1 1 0 Carboxylesterase family ArAE_2_N PF10337.9 KZN88680.1 - 4.7e-71 240.2 19.7 1.6e-55 189.0 0.1 4.4 2 2 1 3 3 3 3 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 KZN88680.1 - 2.1e-16 60.2 17.2 2.1e-16 60.2 17.2 3.4 3 1 1 4 4 4 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 KZN88680.1 - 2.5e-14 53.7 0.0 8.3e-14 52.0 0.0 1.9 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 SnoaL_2 PF12680.7 KZN88681.1 - 0.0037 17.9 0.0 0.0047 17.6 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 KZN88681.1 - 0.11 12.8 0.3 0.17 12.2 0.3 1.4 1 1 0 1 1 1 0 SnoaL-like domain p450 PF00067.22 KZN88682.1 - 3.8e-63 213.9 0.0 5.1e-63 213.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KZN88683.1 - 9.5e-35 120.1 39.5 6e-34 117.5 30.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN88683.1 - 0.24 10.2 44.5 6.3 5.5 44.6 3.1 1 1 0 1 1 1 0 Sugar (and other) transporter MFS_1 PF07690.16 KZN88684.1 - 4.3e-25 88.4 51.5 4.3e-25 88.4 51.5 3.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KZN88684.1 - 1.5e-08 33.6 15.5 2.8e-08 32.7 15.5 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KZN88684.1 - 1.7e-08 33.8 14.8 1.7e-08 33.8 14.8 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter DUF2593 PF10767.9 KZN88684.1 - 0.15 12.2 6.0 0.076 13.1 2.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2593) Sugar_tr PF00083.24 KZN88686.1 - 1.9e-83 280.9 17.3 2.2e-83 280.7 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN88686.1 - 1.9e-33 115.9 39.4 1.5e-31 109.7 19.1 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KZN88686.1 - 4e-05 22.4 0.2 4e-05 22.4 0.2 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein OATP PF03137.20 KZN88686.1 - 0.0032 15.8 0.2 0.0032 15.8 0.2 2.7 2 2 2 4 4 4 1 Organic Anion Transporter Polypeptide (OATP) family DUF3624 PF12292.8 KZN88686.1 - 4.7 7.7 8.5 4 7.9 1.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3624) Pec_lyase_C PF00544.19 KZN88688.1 - 3.6e-17 62.7 13.1 6.8e-16 58.5 13.1 2.2 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KZN88688.1 - 6.4e-08 32.6 28.5 2.1e-05 24.4 14.9 2.3 1 1 1 2 2 2 2 Right handed beta helix region Amidase PF01425.21 KZN88689.1 - 2.1e-71 241.2 0.4 2.8e-67 227.6 0.0 2.1 2 0 0 2 2 2 2 Amidase NmrA PF05368.13 KZN88692.1 - 5e-10 39.3 0.0 8.4e-10 38.6 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KZN88692.1 - 4.7e-06 26.6 0.0 1.1e-05 25.5 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KZN88692.1 - 6.5e-05 22.9 0.0 0.0018 18.3 0.0 2.2 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.12 KZN88692.1 - 0.095 11.9 1.2 4.8 6.3 0.0 2.1 1 1 0 2 2 2 0 Male sterility protein Epimerase PF01370.21 KZN88692.1 - 0.13 11.7 0.0 0.41 10.1 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Fer2_3 PF13085.6 KZN88693.1 - 4.3e-32 110.4 0.0 6.9e-32 109.7 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KZN88693.1 - 2.7e-09 37.4 5.2 2.7e-09 37.4 5.2 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KZN88693.1 - 2.4e-07 30.8 3.1 2.4e-07 30.8 3.1 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KZN88693.1 - 2.7e-07 30.9 7.1 2.7e-07 30.9 7.1 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KZN88693.1 - 0.014 16.0 6.4 0.014 16.0 6.4 2.4 2 2 0 2 2 2 0 4Fe-4S dicluster domain Fer2 PF00111.27 KZN88693.1 - 0.017 15.1 0.7 0.017 15.1 0.7 2.2 3 0 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 KZN88693.1 - 1.6 8.9 12.9 4.5 7.5 9.8 2.8 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 KZN88693.1 - 5.4 7.2 7.9 1.4 9.1 0.1 2.6 3 0 0 3 3 3 0 4Fe-4S dicluster domain p450 PF00067.22 KZN88694.1 - 3.8e-58 197.4 0.0 4.9e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F_bP_aldolase PF01116.20 KZN88696.1 - 4.6e-83 278.9 0.0 5.1e-83 278.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II NAD_binding_11 PF14833.6 KZN88697.1 - 2.5e-38 131.0 3.7 1e-28 100.0 0.0 2.4 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 KZN88697.1 - 9.4e-37 126.6 0.2 2.4e-36 125.3 0.2 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KZN88697.1 - 9.1e-05 23.0 0.3 0.00052 20.5 0.0 2.4 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KZN88697.1 - 0.00058 19.8 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KZN88697.1 - 0.01 15.2 0.1 0.026 13.9 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh PF00984.19 KZN88697.1 - 0.066 13.4 0.0 6.2 7.1 0.0 2.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain RGS PF00615.19 KZN88698.1 - 0.00015 22.0 0.0 0.00045 20.5 0.0 1.8 1 1 0 1 1 1 1 Regulator of G protein signaling domain zf-LITAF-like PF10601.9 KZN88701.1 - 2.1e-21 76.0 10.9 2.9e-21 75.5 10.9 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Ank_2 PF12796.7 KZN88702.1 - 3.2e-34 117.4 0.2 1.8e-10 41.2 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KZN88702.1 - 1.6e-27 92.5 0.0 0.0041 17.5 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 KZN88702.1 - 8.6e-27 93.2 0.2 2.2e-08 34.5 0.0 5.3 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 KZN88702.1 - 1.3e-24 85.5 0.5 0.00088 19.6 0.0 6.9 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 KZN88702.1 - 1.1e-21 76.5 2.0 5.8e-06 26.5 0.4 5.8 1 1 6 7 7 7 6 Ankyrin repeats (many copies) EccE PF11203.8 KZN88702.1 - 0.38 11.1 3.6 6.6 7.1 0.6 2.7 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE Pkinase PF00069.25 KZN88704.1 - 2.7e-14 53.2 0.0 3.4e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Alpha-amylase_C PF02806.18 KZN88705.1 - 5.2e-24 84.5 0.0 1.2e-23 83.3 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 KZN88705.1 - 2.2e-19 69.6 0.1 6.3e-19 68.1 0.1 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KZN88705.1 - 6.9e-15 55.4 0.2 4.9e-11 42.8 0.1 2.6 2 1 1 3 3 3 2 Alpha amylase, catalytic domain ATP-synt_ab PF00006.25 KZN88706.1 - 3.4e-62 209.9 0.0 6.7e-62 208.9 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KZN88706.1 - 4.1e-23 81.7 2.0 2.2e-22 79.3 1.2 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 KZN88706.1 - 0.006 16.0 0.2 0.01 15.2 0.2 1.4 1 0 0 1 1 1 1 KaiC AAA PF00004.29 KZN88706.1 - 0.012 16.0 0.1 1.1 9.7 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KZN88706.1 - 0.019 14.2 0.3 0.1 11.8 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 KZN88706.1 - 0.043 14.1 0.7 0.44 10.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain T3SS_ATPase_C PF18269.1 KZN88706.1 - 0.044 13.7 1.0 0.17 11.7 1.0 1.9 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain RsgA_GTPase PF03193.16 KZN88706.1 - 0.045 13.6 0.3 0.1 12.5 0.1 1.6 2 0 0 2 2 2 0 RsgA GTPase ATPase_2 PF01637.18 KZN88706.1 - 0.049 13.6 0.0 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KZN88706.1 - 0.052 13.5 0.2 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 KZN88706.1 - 0.11 12.9 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF4618 PF15397.6 KZN88706.1 - 0.18 11.2 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) COX4 PF02936.14 KZN88707.1 - 8.7e-46 155.4 0.6 1.1e-45 155.0 0.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3106 PF11304.8 KZN88707.1 - 0.044 14.3 1.2 0.044 14.3 1.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) DUF1104 PF06518.11 KZN88707.1 - 0.13 12.6 0.1 0.27 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) GST_N PF02798.20 KZN88708.1 - 2.1e-15 56.8 0.0 4.1e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KZN88708.1 - 8.9e-15 54.9 0.0 1.9e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KZN88708.1 - 4.4e-14 52.5 0.0 8.3e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KZN88708.1 - 6.6e-05 23.4 0.0 0.00012 22.6 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KZN88708.1 - 0.00015 21.9 0.0 0.00027 21.1 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Luciferase_cat PF10285.9 KZN88708.1 - 0.017 14.5 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Luciferase catalytic domain SH3_9 PF14604.6 KZN88709.1 - 1.5e-05 24.7 0.1 3.4e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF4690 PF15756.5 KZN88709.1 - 0.00094 19.7 0.8 0.0045 17.6 0.0 2.2 2 0 0 2 2 2 1 Small Novel Rich in Cartilage SH3_1 PF00018.28 KZN88709.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 SH3 domain CYYR1 PF10873.8 KZN88709.1 - 0.13 12.8 4.3 0.62 10.5 4.3 2.2 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Podoplanin PF05808.11 KZN88709.1 - 0.16 12.1 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Podoplanin Pmp3 PF01679.17 KZN88710.1 - 2e-18 66.3 10.3 2.6e-18 65.9 10.3 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator GST_N_4 PF17172.4 KZN88711.1 - 1.8e-21 76.7 0.0 2.9e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KZN88711.1 - 3.9e-08 33.0 0.0 6.5e-07 29.0 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KZN88711.1 - 5.7e-06 26.3 0.0 1.4e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KZN88711.1 - 8.7e-06 26.1 0.0 2e-05 24.9 0.0 1.5 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_N_3 PF13417.6 KZN88711.1 - 0.0079 16.6 0.0 0.023 15.1 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain She9_MDM33 PF05546.11 KZN88712.1 - 6.4e-88 293.7 10.6 1e-87 293.1 10.6 1.3 1 0 0 1 1 1 1 She9 / Mdm33 family MSA-2c PF12238.8 KZN88712.1 - 0.031 14.3 2.1 0.081 12.9 2.1 1.7 1 0 0 1 1 1 0 Merozoite surface antigen 2c PsbH PF00737.20 KZN88712.1 - 0.045 13.5 1.1 0.09 12.5 1.1 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein Rieske PF00355.26 KZN88713.1 - 4.1e-11 42.7 0.0 7.5e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 KZN88713.1 - 1.2e-10 41.7 0.4 3e-10 40.4 0.4 1.7 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region CBFD_NFYB_HMF PF00808.23 KZN88714.1 - 4.3e-15 55.8 2.2 5e-15 55.5 0.5 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KZN88714.1 - 0.00065 20.1 0.2 0.00065 20.1 0.2 1.8 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Pol_alpha_B_N PF08418.10 KZN88714.1 - 0.019 15.0 1.0 0.022 14.8 1.0 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Voltage_CLC PF00654.20 KZN88715.1 - 6.4e-88 295.4 30.5 6.4e-88 295.4 30.5 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KZN88715.1 - 1.4e-12 47.8 0.0 2.4e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 CBS domain Sugar_tr PF00083.24 KZN88716.1 - 3.4e-70 237.2 20.1 4e-70 236.9 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN88716.1 - 9.4e-23 80.7 30.8 7.7e-16 58.0 11.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KZN88716.1 - 0.001 17.6 2.9 0.001 17.6 2.9 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_43 PF04616.14 KZN88717.1 - 1.8e-71 240.8 1.2 2.4e-71 240.4 1.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KZN88717.1 - 1.7e-11 44.3 0.0 4.7e-11 42.8 0.0 1.7 2 1 0 2 2 2 1 Beta xylosidase C-terminal Concanavalin A-like domain F-box-like PF12937.7 KZN88718.1 - 0.0029 17.4 0.1 0.012 15.5 0.1 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN88718.1 - 0.041 13.8 1.1 0.23 11.4 0.0 2.8 4 0 0 4 4 4 0 F-box domain F-box_4 PF15966.5 KZN88718.1 - 0.067 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 F-box FAD_binding_3 PF01494.19 KZN88720.1 - 3.1e-19 69.4 0.0 4.3e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KZN88720.1 - 3.8e-07 30.2 0.2 9.1e-07 29.0 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KZN88720.1 - 1.4e-06 27.7 1.3 2.3e-06 26.9 0.8 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KZN88720.1 - 1.8e-06 27.4 0.4 0.00024 20.4 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KZN88720.1 - 5.3e-05 22.8 0.6 0.0001 21.8 0.6 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KZN88720.1 - 0.00016 21.4 4.6 0.017 14.7 3.1 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KZN88720.1 - 0.00019 21.9 1.3 0.0014 19.1 1.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KZN88720.1 - 0.00023 20.0 0.6 0.00086 18.1 0.7 1.7 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KZN88720.1 - 0.00033 19.9 0.4 0.00066 18.9 0.3 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KZN88720.1 - 0.00087 18.6 1.0 0.0014 18.0 1.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KZN88720.1 - 0.0035 16.4 0.3 0.64 9.0 0.5 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KZN88720.1 - 0.055 12.8 0.4 0.12 11.7 0.1 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KZN88720.1 - 0.095 11.9 0.6 0.2 10.8 0.3 1.7 2 0 0 2 2 2 0 Thi4 family FMO-like PF00743.19 KZN88720.1 - 0.36 9.2 0.5 0.56 8.6 0.5 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like EamA PF00892.20 KZN88721.1 - 3.3e-06 27.3 13.1 7.1e-05 23.0 13.1 2.0 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 KZN88721.1 - 0.026 14.6 0.7 0.031 14.3 0.7 1.2 1 0 0 1 1 1 0 Putative transmembrane family 234 PNP_phzG_C PF10590.9 KZN88722.1 - 9.3e-20 70.4 4.1 9.3e-20 70.4 4.1 2.5 3 0 0 3 3 3 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 KZN88722.1 - 2.9e-07 30.6 0.2 0.0015 18.7 0.0 3.0 3 0 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase PPR_2 PF13041.6 KZN88723.1 - 2.1e-42 143.1 5.4 2.3e-09 37.3 0.0 12.6 11 3 3 14 14 14 6 PPR repeat family PPR_3 PF13812.6 KZN88723.1 - 3e-29 100.9 2.0 0.0028 17.7 0.0 11.2 7 5 6 13 13 13 7 Pentatricopeptide repeat domain PPR PF01535.20 KZN88723.1 - 3.3e-25 86.5 19.8 0.0011 19.0 0.0 13.5 15 2 0 15 15 14 6 PPR repeat PPR_long PF17177.4 KZN88723.1 - 2.3e-19 69.6 14.8 1.9e-09 37.2 0.1 7.2 5 1 0 6 6 6 4 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KZN88723.1 - 1.4e-18 66.3 3.1 1.7e-05 24.4 0.1 10.0 12 0 0 12 12 12 3 PPR repeat RPM2 PF08579.11 KZN88723.1 - 4.3e-07 30.4 0.0 0.00019 21.9 0.0 4.2 4 1 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_19 PF14559.6 KZN88723.1 - 0.0031 18.0 12.9 0.77 10.3 0.0 6.0 5 1 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KZN88723.1 - 0.055 14.3 16.2 20 6.4 0.0 10.2 11 2 1 12 12 10 0 Tetratricopeptide repeat ATP13 PF12921.7 KZN88723.1 - 0.11 12.3 0.0 33 4.4 0.0 3.4 4 0 0 4 4 4 0 Mitochondrial ATPase expression CHAD PF05235.14 KZN88723.1 - 1.6 8.7 9.0 1.2 9.1 0.0 3.4 5 0 0 5 5 5 0 CHAD domain TPR_7 PF13176.6 KZN88723.1 - 6.5 7.0 8.7 6.8 7.0 0.1 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat Methyltransf_11 PF08241.12 KZN88724.1 - 1.4e-22 80.2 0.0 2.9e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN88724.1 - 1.6e-21 76.8 0.0 5.3e-21 75.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN88724.1 - 1.2e-18 67.4 0.0 2e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN88724.1 - 1.6e-14 54.1 0.0 2.5e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN88724.1 - 2e-12 47.7 0.0 4.2e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KZN88724.1 - 2.4e-12 46.7 0.0 3.3e-11 43.0 0.0 2.0 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KZN88724.1 - 5.5e-11 42.3 0.0 7.6e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 KZN88724.1 - 2e-06 27.5 0.0 3.6e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 KZN88724.1 - 3.5e-06 26.7 0.0 5.6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KZN88724.1 - 0.0016 18.4 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KZN88724.1 - 0.0024 17.4 0.0 0.0045 16.5 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 KZN88724.1 - 0.0024 17.3 0.0 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KZN88724.1 - 0.007 15.7 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_9 PF08003.11 KZN88724.1 - 0.0078 15.2 0.1 0.081 11.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) TehB PF03848.14 KZN88724.1 - 0.0086 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.19 KZN88724.1 - 0.01 15.6 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_29 PF03141.16 KZN88724.1 - 0.02 13.5 0.0 0.027 13.0 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.15 KZN88724.1 - 0.021 14.7 0.0 0.21 11.4 0.0 2.1 1 1 0 1 1 1 0 Hypothetical methyltransferase AlaDh_PNT_C PF01262.21 KZN88724.1 - 0.037 13.3 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain RrnaAD PF00398.20 KZN88724.1 - 0.063 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DOT1 PF08123.13 KZN88724.1 - 0.087 12.3 0.0 0.2 11.1 0.0 1.6 2 0 0 2 2 1 0 Histone methylation protein DOT1 GHMP_kinases_N PF00288.26 KZN88725.1 - 2.5e-14 53.2 2.6 6.5e-14 51.9 2.6 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KZN88725.1 - 1.8e-09 37.8 0.1 1.9e-08 34.6 0.0 2.6 2 2 0 2 2 2 1 GHMP kinases C terminal DUF4763 PF15960.5 KZN88725.1 - 0.0029 16.9 0.3 0.0044 16.4 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) Rad60-SLD_2 PF13881.6 KZN88726.1 - 9.6e-12 45.0 0.0 1.8e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KZN88726.1 - 0.004 17.7 0.0 0.011 16.3 0.0 1.7 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KZN88726.1 - 0.027 14.2 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family Ndc1_Nup PF09531.10 KZN88726.1 - 2.4 6.8 4.8 2.7 6.6 4.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UMP1 PF05348.11 KZN88727.1 - 1.9e-36 124.9 0.0 2.6e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Ribosom_S12_S23 PF00164.25 KZN88728.1 - 1.7e-28 98.5 0.5 2.4e-28 98.0 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 LIME1 PF15332.6 KZN88728.1 - 0.092 12.3 0.0 0.098 12.2 0.0 1.1 1 0 0 1 1 1 0 Lck-interacting transmembrane adapter 1 Glyco_transf_15 PF01793.16 KZN88729.1 - 3.3e-127 424.2 10.0 4.1e-127 423.9 10.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PAT1 PF09770.9 KZN88730.1 - 0 1181.2 1.6 0 1179.9 1.6 1.6 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 GDP_Man_Dehyd PF16363.5 KZN88731.1 - 7.6e-48 163.6 0.0 2.3e-47 162.0 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KZN88731.1 - 9.8e-47 159.4 0.0 1.6e-46 158.8 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KZN88731.1 - 6.6e-16 58.1 0.0 1.1e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KZN88731.1 - 1.2e-11 44.3 0.0 6.5e-10 38.6 0.0 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KZN88731.1 - 9.6e-11 41.3 0.0 1.5e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KZN88731.1 - 1.8e-09 37.3 0.0 4.5e-09 36.1 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KZN88731.1 - 3.3e-06 27.1 0.0 6.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KZN88731.1 - 1.4e-05 25.0 0.0 2.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short_C2 PF13561.6 KZN88731.1 - 0.00031 20.4 0.0 0.00054 19.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.12 KZN88731.1 - 0.0007 18.8 0.0 0.0054 15.9 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KZN88731.1 - 0.071 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.25 KZN88732.1 - 6.7e-16 58.3 0.0 9.7e-13 48.0 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KZN88732.1 - 4.9e-06 26.6 0.0 9.7e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KZN88732.1 - 1.3e-05 24.8 0.0 2.6e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 KZN88732.1 - 1.5e-05 24.7 0.0 6e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 KZN88732.1 - 0.069 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Glyco_trans_4_4 PF13579.6 KZN88732.1 - 0.08 13.4 0.4 0.23 11.9 0.1 1.9 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain E1-N PF14463.6 KZN88732.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 E1 N-terminal domain RmlD_sub_bind PF04321.17 KZN88732.1 - 0.16 11.0 1.3 0.24 10.4 0.0 1.9 3 0 0 3 3 3 0 RmlD substrate binding domain G-patch PF01585.23 KZN88733.1 - 2.4e-05 24.2 0.0 4.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 G-patch domain Mito_fiss_reg PF05308.11 KZN88733.1 - 2.4 8.2 9.3 14 5.7 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator Sec1 PF00995.23 KZN88734.1 - 1.1e-114 384.8 0.0 1.4e-114 384.5 0.0 1.1 1 0 0 1 1 1 1 Sec1 family SUV3_C PF12513.8 KZN88735.1 - 1.6e-17 63.1 0.2 3.5e-17 62.1 0.2 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 KZN88735.1 - 1.2e-10 41.7 0.0 2.3e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 KZN88735.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Suv3 C-terminal domain 1 HA2 PF04408.23 KZN88736.1 - 2.2e-24 85.8 1.1 6.7e-24 84.3 0.1 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KZN88736.1 - 2e-20 72.9 0.0 4e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KZN88736.1 - 1.5e-13 51.0 0.0 3.7e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 KZN88736.1 - 4e-11 43.1 0.7 8.1e-11 42.1 0.7 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 KZN88736.1 - 0.00017 21.4 0.2 0.00052 19.8 0.2 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 KZN88736.1 - 0.00053 19.1 0.0 0.0011 18.1 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 KZN88736.1 - 0.0012 19.2 0.0 0.003 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KZN88736.1 - 0.0029 17.3 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KZN88736.1 - 0.028 14.8 0.1 0.057 13.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KZN88736.1 - 0.06 12.7 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.6 KZN88736.1 - 0.19 11.5 0.0 0.56 10.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KZN88736.1 - 0.21 12.1 0.4 1.9 9.0 0.2 2.5 1 1 1 2 2 2 0 ABC transporter Npa1 PF11707.8 KZN88737.1 - 7.1e-96 321.5 0.0 2.4e-95 319.8 0.0 2.0 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KZN88737.1 - 1.3e-56 191.3 0.0 5.2e-56 189.4 0.0 2.1 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 MMS22L_C PF14911.6 KZN88737.1 - 0.022 13.9 1.2 0.057 12.5 0.3 2.1 2 0 0 2 2 2 0 S-phase genomic integrity recombination mediator, C-terminal MFS_1 PF07690.16 KZN88738.1 - 3e-32 111.9 32.1 4e-32 111.5 32.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MASE2 PF05230.11 KZN88738.1 - 0.56 10.3 6.4 2 8.5 0.3 2.9 3 0 0 3 3 3 0 MASE2 domain F-box-like PF12937.7 KZN88739.1 - 0.00011 22.0 0.0 0.00028 20.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN88739.1 - 0.0002 21.1 0.2 0.0015 18.4 0.2 2.4 1 1 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KZN88739.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 F-box ADH_N PF08240.12 KZN88740.1 - 2.6e-28 98.0 2.9 4.9e-28 97.2 2.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN88740.1 - 7.9e-18 64.7 0.0 1.7e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KZN88740.1 - 6.3e-08 33.8 0.0 1.2e-07 32.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KZN88740.1 - 6.7e-07 29.0 0.2 3.1e-06 26.8 0.1 1.9 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 KZN88740.1 - 0.063 13.2 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated 2-Hacid_dh_C PF02826.19 KZN88740.1 - 0.069 12.5 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KZN88740.1 - 0.078 12.3 1.6 0.21 10.9 0.3 2.1 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Aa_trans PF01490.18 KZN88741.1 - 9.6e-56 189.2 38.8 1.1e-55 189.1 38.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MFS_1 PF07690.16 KZN88743.1 - 4.4e-08 32.4 39.8 2e-07 30.3 19.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GPI-anchored PF10342.9 KZN88745.1 - 1.4e-13 51.4 3.1 1.4e-13 51.4 3.1 3.1 3 1 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GREB1 PF15782.5 KZN88745.1 - 2.6 5.0 18.6 2.8 4.9 18.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RMP PF14996.6 KZN88745.1 - 5.6 7.2 5.9 4.3 7.6 4.2 1.7 1 1 0 1 1 1 0 Retinal Maintenance Alpha-amylase PF00128.24 KZN88746.1 - 1.2e-47 163.2 0.0 2.3e-47 162.2 0.0 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KZN88746.1 - 1.2e-21 76.8 0.4 2.1e-21 76.0 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Alpha-amylase PF00128.24 KZN88747.1 - 4.1e-20 72.6 0.0 1e-18 68.0 0.0 2.4 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 KZN88747.1 - 4.6e-15 56.0 0.1 7.7e-15 55.3 0.1 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KZN88747.1 - 9e-06 25.3 0.0 1.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KZN88747.1 - 0.05 13.6 0.2 0.14 12.2 0.1 1.7 2 0 0 2 2 2 0 Glycosyltransferase Family 4 PhageMin_Tail PF10145.9 KZN88748.1 - 0.0049 16.8 1.4 0.01 15.7 1.4 1.5 1 1 0 1 1 1 1 Phage-related minor tail protein DUF2433 PF10360.9 KZN88748.1 - 0.074 13.1 0.5 0.17 12.0 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2433) DUF1772 PF08592.11 KZN88749.1 - 3.4e-23 82.5 1.0 5.1e-23 81.9 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Pro_CA PF00484.19 KZN88750.1 - 9.5e-51 172.2 0.0 1.3e-50 171.7 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase DUF3824 PF12868.7 KZN88752.1 - 1.2e-07 32.6 5.5 1.2e-07 32.6 5.5 4.8 2 2 2 4 4 4 2 Domain of unknwon function (DUF3824) Helo_like_N PF17111.5 KZN88752.1 - 0.025 13.9 5.2 0.049 13.0 5.2 1.5 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins E1-E2_ATPase PF00122.20 KZN88753.1 - 1.2e-44 152.0 2.9 2.9e-44 150.7 2.9 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KZN88753.1 - 2.5e-24 86.8 0.0 4.1e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KZN88753.1 - 8.7e-08 32.5 0.7 6.4e-07 29.7 0.2 2.6 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KZN88753.1 - 9.7e-05 22.2 0.4 0.0033 17.2 0.2 2.4 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase YjeF_N PF03853.15 KZN88753.1 - 0.0046 16.9 0.4 3.3 7.6 0.1 2.9 3 0 0 3 3 3 2 YjeF-related protein N-terminus Saw1 PF11561.8 KZN88755.1 - 0.89 9.0 5.8 1.4 8.4 5.8 1.3 1 0 0 1 1 1 0 Single strand annealing-weakened 1 Pox_Ag35 PF03286.14 KZN88755.1 - 3.6 7.3 11.5 0.38 10.5 7.1 1.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein SNF2_N PF00176.23 KZN88756.1 - 2.2e-48 164.8 0.0 3.7e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KZN88756.1 - 0.001 19.4 0.0 0.0021 18.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 KZN88756.1 - 0.0017 18.2 1.9 0.0017 18.2 1.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KZN88756.1 - 0.0017 18.2 1.3 0.0046 16.8 1.3 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 SWI2_SNF2 PF18766.1 KZN88756.1 - 0.0059 16.3 0.0 0.022 14.4 0.0 2.0 1 0 0 1 1 1 1 SWI2/SNF2 ATPase zf-C3HC4 PF00097.25 KZN88756.1 - 0.014 15.3 3.0 0.038 13.9 3.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KZN88756.1 - 0.033 14.0 1.6 0.088 12.7 1.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KZN88756.1 - 0.038 14.0 3.7 0.11 12.5 3.7 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KZN88756.1 - 0.061 13.3 0.7 0.19 11.8 0.7 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 KZN88756.1 - 0.36 11.2 4.4 1 9.8 4.4 1.8 1 0 0 1 1 1 0 Ring finger domain SNF2_N PF00176.23 KZN88757.1 - 6.8e-44 150.0 1.1 3.8e-43 147.5 0.1 2.1 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KZN88757.1 - 1.6e-14 54.2 0.0 6.6e-14 52.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 KZN88757.1 - 1.9e-07 30.9 8.5 3.7e-07 30.0 8.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.15 KZN88757.1 - 9.4e-07 29.0 0.0 2.2e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 KZN88757.1 - 0.0021 17.9 6.2 0.0048 16.7 6.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KZN88757.1 - 0.017 14.9 5.4 0.063 13.1 5.4 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KZN88757.1 - 0.03 14.2 3.1 0.085 12.7 3.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KZN88757.1 - 0.037 14.4 7.8 0.083 13.2 7.8 1.7 1 0 0 1 1 1 0 Ring finger domain AAA_34 PF13872.6 KZN88757.1 - 0.039 12.9 0.0 0.066 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 zf-RING_UBOX PF13445.6 KZN88757.1 - 0.046 13.7 4.0 0.12 12.4 4.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 KZN88757.1 - 0.62 10.0 7.9 1.5 8.7 7.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KZN88757.1 - 0.84 9.8 6.8 2 8.6 6.8 1.7 1 0 0 1 1 1 0 FYVE zinc finger Zn_ribbon_17 PF17120.5 KZN88757.1 - 2.6 7.7 7.0 8.4 6.1 7.0 2.0 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type DZR PF12773.7 KZN88757.1 - 6.4 6.9 8.3 71 3.5 0.6 2.6 1 1 1 2 2 2 0 Double zinc ribbon FNIP PF05725.12 KZN88758.1 - 0.18 12.0 1.7 14 6.0 1.0 2.6 2 0 0 2 2 2 0 FNIP Repeat RSN1_7TM PF02714.15 KZN88759.1 - 6.9e-91 304.4 19.8 6.9e-91 304.4 19.8 2.9 4 0 0 4 4 4 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KZN88759.1 - 7.3e-44 149.3 5.6 7.3e-44 149.3 5.6 2.6 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KZN88759.1 - 1.2e-35 123.3 0.3 1.8e-35 122.7 0.3 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KZN88759.1 - 8e-33 112.5 0.3 4.4e-32 110.1 0.2 2.1 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter DUF3377 PF11857.8 KZN88759.1 - 0.1 12.5 8.6 0.31 11.0 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) CCSMST1 PF15013.6 KZN88759.1 - 0.22 11.7 0.0 0.22 11.7 0.0 2.5 3 0 0 3 3 3 0 CCSMST1 family IFRD_C PF04836.12 KZN88759.1 - 0.25 12.0 0.8 0.53 10.9 0.8 1.5 1 0 0 1 1 1 0 Interferon-related protein conserved region DUF4349 PF14257.6 KZN88759.1 - 6.9 6.1 6.1 1.2 8.5 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4349) MCM PF00493.23 KZN88762.1 - 5.4e-98 326.5 0.0 8.7e-98 325.9 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KZN88762.1 - 2e-39 134.3 0.2 4.5e-39 133.2 0.2 1.6 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 KZN88762.1 - 8.8e-33 112.8 0.3 3e-32 111.1 0.3 2.0 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 KZN88762.1 - 3.2e-24 85.2 0.2 1.1e-23 83.5 0.2 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KZN88762.1 - 9.3e-17 61.5 1.3 2.7e-16 60.1 0.1 2.4 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.21 KZN88762.1 - 4.2e-05 23.0 0.0 0.00019 20.9 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KZN88762.1 - 0.0045 17.0 0.0 0.01 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KZN88762.1 - 0.0047 16.8 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KZN88762.1 - 0.0094 15.7 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain CCDC53 PF10152.9 KZN88763.1 - 0.024 15.1 8.4 0.037 14.5 1.6 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex LXG PF04740.12 KZN88764.1 - 0.011 15.5 0.2 0.016 14.9 0.2 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily FAM184 PF15665.5 KZN88764.1 - 0.019 14.8 0.3 0.03 14.1 0.3 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B FAM220 PF15487.6 KZN88764.1 - 0.04 13.6 2.7 0.059 13.0 2.7 1.3 1 0 0 1 1 1 0 FAM220 family DUF1664 PF07889.12 KZN88764.1 - 0.052 13.6 0.4 0.11 12.6 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) KNTase_C PF07827.11 KZN88764.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 KNTase C-terminal domain DHR10 PF18595.1 KZN88764.1 - 0.22 11.6 2.1 8.1 6.5 0.2 2.5 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Pyridox_oxase_2 PF12766.7 KZN88765.1 - 1.4e-28 99.4 0.0 2.8e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF4508 PF14969.6 KZN88766.1 - 0.16 12.2 1.4 0.25 11.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4508) DUF3716 PF12511.8 KZN88767.1 - 3.2e-12 46.3 5.1 4.6e-12 45.8 5.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) AMP-binding PF00501.28 KZN88768.1 - 0 1292.8 0.6 2.4e-76 257.0 0.0 7.8 6 1 0 6 6 6 6 AMP-binding enzyme Condensation PF00668.20 KZN88768.1 - 0 1030.3 0.0 5.1e-55 187.0 0.0 9.6 9 1 0 9 9 9 7 Condensation domain PP-binding PF00550.25 KZN88768.1 - 4.8e-77 254.3 6.1 3.5e-11 43.3 0.0 7.9 7 0 0 7 7 7 7 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KZN88768.1 - 1.8e-13 51.3 0.0 0.2 12.6 0.0 6.1 5 0 0 5 5 5 4 AMP-binding enzyme C-terminal domain Transferase PF02458.15 KZN88768.1 - 0.0095 14.6 0.0 15 4.1 0.0 3.7 4 0 0 4 4 4 2 Transferase family AATase PF07247.12 KZN88768.1 - 0.034 12.7 0.0 2.7 6.4 0.0 3.0 3 0 0 3 3 3 0 Alcohol acetyltransferase DUF5122 PF17164.4 KZN88768.1 - 0.53 10.6 1.7 21 5.5 0.2 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller NAT PF04768.13 KZN88769.1 - 2.8e-12 46.6 0.0 6.6e-12 45.4 0.0 1.6 1 1 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 KZN88769.1 - 8.2e-08 32.1 0.0 9.7e-07 28.6 0.0 2.3 2 1 0 2 2 2 1 Amino acid kinase family Tom7 PF08038.12 KZN88769.1 - 0.0046 16.6 0.0 0.022 14.4 0.0 2.0 2 0 0 2 2 2 1 TOM7 family Ank_4 PF13637.6 KZN88770.1 - 1e-17 64.2 1.2 1.3e-11 44.8 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KZN88770.1 - 2.3e-14 53.7 0.5 3.3e-14 53.2 0.5 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KZN88770.1 - 5.2e-14 52.1 1.7 5.1e-06 26.7 0.4 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KZN88770.1 - 4.1e-12 46.0 2.0 8.6e-05 22.8 0.4 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KZN88770.1 - 2.4e-09 36.6 0.5 0.0025 18.1 0.1 2.7 3 0 0 3 3 3 2 Ankyrin repeat Aminotran_4 PF01063.19 KZN88771.1 - 1.8e-24 86.9 0.0 2.2e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV p450 PF00067.22 KZN88772.1 - 4.7e-72 243.2 0.0 6.4e-72 242.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fas_alpha_ACP PF18325.1 KZN88773.1 - 6.8e-56 189.1 0.0 1.5e-55 188.0 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 KZN88773.1 - 5.2e-38 130.7 0.0 1.8e-37 128.9 0.0 1.9 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 KZN88773.1 - 8e-20 71.5 0.1 1.6e-19 70.5 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KZN88773.1 - 6.8e-14 51.9 0.0 2.9e-13 49.9 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KZN88773.1 - 0.0034 16.8 0.1 0.0073 15.7 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain RcpB PF16971.5 KZN88773.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Rough colony protein B, tight adherence - tad - subunit ABC_tran PF00005.27 KZN88774.1 - 1.2e-46 158.6 0.0 2.4e-26 92.9 0.0 2.7 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KZN88774.1 - 2.4e-31 109.4 33.6 4.4e-28 98.7 13.7 3.0 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KZN88774.1 - 3.8e-09 36.3 0.5 7.8e-06 25.5 0.2 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KZN88774.1 - 3.1e-08 33.8 0.4 0.36 10.6 0.0 4.4 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KZN88774.1 - 7.1e-06 26.0 0.2 0.078 12.9 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KZN88774.1 - 2.4e-05 24.0 0.2 0.17 11.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KZN88774.1 - 3.3e-05 24.2 0.5 0.04 14.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 KZN88774.1 - 3.4e-05 23.9 0.3 0.11 12.6 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KZN88774.1 - 0.00013 22.4 0.1 0.73 10.2 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.6 KZN88774.1 - 0.00019 21.6 0.8 0.15 12.3 0.2 3.2 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KZN88774.1 - 0.0004 20.6 0.0 0.11 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KZN88774.1 - 0.0041 17.3 0.5 0.57 10.2 0.3 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_23 PF13476.6 KZN88774.1 - 0.0051 17.3 0.1 2.4 8.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KZN88774.1 - 0.006 16.3 0.1 2.5 7.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KZN88774.1 - 0.0066 16.2 0.0 2.5 7.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 KZN88774.1 - 0.011 16.1 0.0 7.4 7.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.15 KZN88774.1 - 0.021 14.8 0.1 0.24 11.3 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_18 PF13238.6 KZN88774.1 - 0.026 15.1 0.0 6.1 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KZN88774.1 - 0.031 14.1 0.0 6.6 6.4 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATP-synt_ab PF00006.25 KZN88774.1 - 0.04 13.6 0.3 8.4 6.0 0.0 2.7 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 KZN88774.1 - 0.043 14.3 0.1 2.5 8.5 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KZN88774.1 - 0.044 13.3 0.1 11 5.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 KZN88774.1 - 0.049 13.7 0.4 8.3 6.4 0.0 2.5 2 0 0 2 2 2 0 Dynamin family Septin PF00735.18 KZN88774.1 - 0.05 12.9 0.2 5.1 6.3 0.1 2.3 2 0 0 2 2 2 0 Septin Viral_helicase1 PF01443.18 KZN88774.1 - 0.05 13.3 0.0 12 5.5 0.0 3.1 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 KZN88774.1 - 0.051 12.7 0.0 11 5.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.14 KZN88774.1 - 0.072 13.1 0.2 11 6.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 KZN88774.1 - 0.076 12.9 0.6 2 8.3 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.6 KZN88774.1 - 0.11 12.1 0.0 4.7 6.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 KZN88774.1 - 0.16 11.9 0.4 22 4.9 0.0 2.9 3 0 0 3 3 3 0 NACHT domain DUF1729 PF08354.10 KZN88775.1 - 4.7e-150 499.4 0.0 6.4e-150 498.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 KZN88775.1 - 1.3e-63 215.5 0.0 4.3e-63 213.7 0.0 1.9 3 0 0 3 3 3 1 Acyl transferase domain FAS_meander PF17951.1 KZN88775.1 - 2e-41 141.2 0.0 5.3e-41 139.8 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 KZN88775.1 - 6.8e-36 124.2 0.0 1.6e-35 123.0 0.0 1.7 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 KZN88775.1 - 4.5e-26 90.8 0.0 8.7e-26 89.9 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain FAS_N PF17828.1 KZN88775.1 - 1e-13 51.4 0.0 2.8e-13 50.0 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydrat_N PF13452.6 KZN88775.1 - 7.2e-13 48.8 0.1 3e-11 43.6 0.0 2.7 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase RTA1 PF04479.13 KZN88776.1 - 3e-47 160.9 8.9 3e-47 160.9 8.9 1.4 1 1 0 1 1 1 1 RTA1 like protein Ank_2 PF12796.7 KZN88777.1 - 3.3e-29 101.3 0.1 2.7e-18 66.3 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KZN88777.1 - 1.5e-26 91.6 0.6 6.8e-06 26.3 0.5 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KZN88777.1 - 1.9e-25 88.9 1.2 2.6e-11 43.8 0.1 3.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KZN88777.1 - 3.1e-22 78.3 0.7 1.3e-06 28.5 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN88777.1 - 5.1e-21 72.5 0.2 0.00059 20.1 0.1 4.3 4 0 0 4 4 4 4 Ankyrin repeat bZIP_1 PF00170.21 KZN88777.1 - 0.037 14.1 2.0 0.061 13.4 2.0 1.2 1 0 0 1 1 1 0 bZIP transcription factor Asp PF00026.23 KZN88778.1 - 2.5e-41 142.2 0.5 3.2e-41 141.8 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KZN88778.1 - 9.6e-06 26.2 0.6 0.004 17.8 0.4 3.5 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KZN88778.1 - 0.00037 21.0 0.9 0.11 13.1 0.3 3.3 3 1 0 3 3 3 2 gag-polyprotein putative aspartyl protease GMC_oxred_N PF00732.19 KZN88779.1 - 8.1e-64 215.8 0.0 9.8e-64 215.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KZN88779.1 - 1.1e-33 116.7 0.0 2e-33 115.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KZN88779.1 - 1.1e-05 24.7 0.1 0.01 15.0 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KZN88779.1 - 6e-05 22.4 0.3 0.0019 17.5 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN88779.1 - 0.00017 21.7 0.1 0.00089 19.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KZN88779.1 - 0.00021 21.0 0.2 0.0031 17.1 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KZN88779.1 - 0.00036 19.9 0.2 0.8 8.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KZN88779.1 - 0.0013 17.9 0.0 0.0026 16.9 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 KZN88779.1 - 0.0028 16.4 0.2 0.04 12.6 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 KZN88779.1 - 0.011 15.7 2.7 0.13 12.2 0.1 2.8 2 1 1 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.17 KZN88779.1 - 0.024 13.9 0.1 0.043 13.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 KZN88779.1 - 0.026 15.1 0.4 0.15 12.7 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Arr-ms PF12120.8 KZN88779.1 - 0.084 13.1 0.0 0.33 11.2 0.0 2.0 1 0 0 1 1 1 0 Rifampin ADP-ribosyl transferase TrkA_N PF02254.18 KZN88779.1 - 0.1 12.9 0.1 0.24 11.6 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.14 KZN88779.1 - 0.1 11.4 0.3 0.17 10.7 0.3 1.3 1 0 0 1 1 1 0 Tryptophan halogenase MFS_1 PF07690.16 KZN88780.1 - 5.6e-36 124.2 31.7 5.6e-36 124.2 31.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Amidohydro_1 PF01979.20 KZN88781.1 - 1.3e-43 149.7 0.1 1.5e-43 149.5 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KZN88781.1 - 1.5e-20 74.1 0.2 2.5e-14 53.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family DHO_dh PF01180.21 KZN88781.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Fungal_trans PF04082.18 KZN88782.1 - 1.5e-20 73.3 0.2 3e-19 69.1 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain OmdA PF13376.6 KZN88783.1 - 0.088 12.8 0.0 0.33 11.0 0.0 2.0 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated HET PF06985.11 KZN88785.1 - 1e-08 35.7 1.8 1.8e-06 28.3 0.0 3.1 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) DUF953 PF06110.11 KZN88787.1 - 5e-12 45.5 0.0 5.7e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 KZN88787.1 - 0.00048 19.9 0.0 0.00068 19.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin FAD_binding_4 PF01565.23 KZN88788.1 - 4.2e-20 71.9 0.3 7.1e-20 71.2 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KZN88788.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like PQQ_3 PF13570.6 KZN88790.1 - 0.028 14.9 0.1 0.18 12.3 0.0 2.5 2 0 0 2 2 2 0 PQQ-like domain LRR_9 PF14580.6 KZN88791.1 - 9.1e-60 201.1 0.0 1.4e-59 200.5 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 KZN88791.1 - 4.4e-07 29.6 2.3 1.8e-06 27.6 2.3 2.1 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KZN88791.1 - 6e-05 23.3 7.2 0.0019 18.6 1.4 3.4 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) Gp-FAR-1 PF05823.12 KZN88791.1 - 0.005 17.2 0.1 0.0079 16.6 0.1 1.2 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF4349 PF14257.6 KZN88791.1 - 0.049 13.1 1.5 0.1 12.0 1.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) GDA1_CD39 PF01150.17 KZN88792.1 - 1.1e-104 350.5 0.0 1.5e-104 350.0 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ammonium_transp PF00909.21 KZN88793.1 - 1.1e-111 373.4 25.9 1.3e-111 373.2 25.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family AAA PF00004.29 KZN88796.1 - 2.2e-48 164.0 0.0 9.6e-42 142.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KZN88796.1 - 2.7e-10 39.9 0.2 1.2e-09 37.8 0.0 2.2 3 0 0 3 3 1 1 AAA+ lid domain IstB_IS21 PF01695.17 KZN88796.1 - 1.4e-07 31.4 0.0 1.2e-05 25.1 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 KZN88796.1 - 2.8e-06 27.6 0.0 1e-05 25.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KZN88796.1 - 4.4e-06 27.2 2.3 8.4e-05 23.0 0.0 3.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KZN88796.1 - 5.8e-05 23.1 0.0 0.0018 18.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Bromodomain PF00439.25 KZN88796.1 - 0.0011 19.0 0.0 0.0031 17.5 0.0 1.7 1 0 0 1 1 1 1 Bromodomain RNA_helicase PF00910.22 KZN88796.1 - 0.0025 18.2 0.0 0.0078 16.6 0.0 1.9 1 0 0 1 1 1 1 RNA helicase Sigma54_activ_2 PF14532.6 KZN88796.1 - 0.0026 17.9 0.0 0.7 10.0 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_30 PF13604.6 KZN88796.1 - 0.0032 17.2 0.0 0.0089 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KZN88796.1 - 0.0036 17.6 0.1 0.069 13.4 0.1 2.9 2 1 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 KZN88796.1 - 0.015 14.7 0.1 0.17 11.3 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KZN88796.1 - 0.017 14.9 0.0 0.075 12.8 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 KZN88796.1 - 0.018 14.6 0.0 0.053 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KZN88796.1 - 0.019 15.0 0.0 0.067 13.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KZN88796.1 - 0.02 14.1 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_33 PF13671.6 KZN88796.1 - 0.023 14.9 0.0 0.11 12.7 0.0 2.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KZN88796.1 - 0.03 14.9 0.0 0.12 12.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KZN88796.1 - 0.045 13.5 0.0 1.1 8.9 0.0 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.11 KZN88796.1 - 0.06 13.2 0.0 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 KZN88796.1 - 0.063 12.4 0.0 0.24 10.4 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 KZN88796.1 - 0.077 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KZN88796.1 - 0.099 13.2 0.0 0.44 11.0 0.0 2.2 1 0 0 1 1 1 0 ABC transporter ResIII PF04851.15 KZN88796.1 - 0.11 12.4 0.0 0.47 10.4 0.0 2.0 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 KZN88796.1 - 0.25 11.1 0.0 0.25 11.1 0.0 3.6 3 0 0 3 3 2 0 AAA domain Sec66 PF09802.9 KZN88797.1 - 1.9e-82 275.2 0.9 2.3e-82 275.0 0.9 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 PPR_2 PF13041.6 KZN88798.1 - 0.00026 21.1 0.8 19 5.6 0.0 5.2 6 0 0 6 6 6 2 PPR repeat family HTH_AsnC-type PF13404.6 KZN88798.1 - 0.097 12.5 1.0 0.56 10.1 0.4 2.5 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain TPR_14 PF13428.6 KZN88798.1 - 0.81 10.7 0.0 0.81 10.7 0.0 3.9 4 1 1 5 5 5 0 Tetratricopeptide repeat ORC3_N PF07034.11 KZN88799.1 - 2.3e-38 132.2 0.0 1.1e-36 126.6 0.0 2.2 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 KZN88799.1 - 2.2e-23 82.9 2.4 3e-15 56.5 0.0 2.7 2 1 1 3 3 3 2 Origin recognition complex winged helix C-terminal Nop14 PF04147.12 KZN88801.1 - 4e-292 971.6 37.0 4.7e-292 971.4 37.0 1.0 1 0 0 1 1 1 1 Nop14-like family COesterase PF00135.28 KZN88802.1 - 1.5e-89 301.3 0.0 1.8e-89 301.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KZN88802.1 - 1.2e-08 35.1 0.2 7.5e-08 32.5 0.2 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KZN88802.1 - 0.00067 19.2 0.1 0.001 18.6 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF4187 PF13821.6 KZN88803.1 - 1e-20 73.2 2.9 2.5e-20 72.0 2.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KZN88803.1 - 1.1e-07 31.6 0.0 3.7e-07 29.9 0.0 1.9 1 1 0 1 1 1 1 G-patch domain DUF4407 PF14362.6 KZN88803.1 - 7.4 5.8 13.7 0.25 10.7 5.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DbpA PF03880.15 KZN88806.1 - 0.018 15.0 0.1 0.056 13.4 0.1 1.8 2 0 0 2 2 2 0 DbpA RNA binding domain Peptidase_S49_N PF08496.10 KZN88807.1 - 0.96 9.5 8.5 1.9 8.5 5.3 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal MFS_1 PF07690.16 KZN88808.1 - 2.9e-33 115.2 15.6 2.9e-33 115.2 15.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN88808.1 - 4.5e-10 39.0 3.4 4.5e-10 39.0 3.4 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter LacY_symp PF01306.19 KZN88808.1 - 1.6e-05 23.9 10.3 0.00068 18.5 4.2 2.3 2 0 0 2 2 2 2 LacY proton/sugar symporter TRI12 PF06609.13 KZN88808.1 - 0.00025 19.6 0.5 0.00044 18.8 0.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KZN88808.1 - 0.0003 19.8 0.9 0.0003 19.8 0.9 2.4 2 0 0 2 2 2 1 MFS_1 like family MFS_5 PF05631.14 KZN88808.1 - 0.0067 15.4 0.1 0.013 14.4 0.1 1.4 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_3 PF05977.13 KZN88808.1 - 0.036 12.5 9.3 0.046 12.1 2.2 2.6 2 1 1 3 3 3 0 Transmembrane secretion effector Fungal_TACC PF12709.7 KZN88809.1 - 2.4e-12 47.1 16.7 8.1e-10 39.0 3.0 4.1 4 0 0 4 4 4 2 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4407 PF14362.6 KZN88809.1 - 0.14 11.5 33.4 0.029 13.7 8.3 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) FlxA PF14282.6 KZN88809.1 - 0.27 11.2 9.2 0.85 9.6 1.9 3.0 2 1 0 2 2 2 0 FlxA-like protein Filament PF00038.21 KZN88809.1 - 4.1 6.9 37.3 34 3.9 37.3 2.4 1 1 0 1 1 1 0 Intermediate filament protein DUF4776 PF16003.5 KZN88809.1 - 4.9 6.0 13.4 8.7 5.2 13.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Fez1 PF06818.15 KZN88809.1 - 8.7 6.7 40.8 5.4 7.4 18.5 2.7 1 1 1 2 2 2 0 Fez1 DUF4094 PF13334.6 KZN88809.1 - 10 6.7 11.3 1.3 9.5 1.7 3.5 2 2 2 4 4 4 0 Domain of unknown function (DUF4094) Fungal_trans PF04082.18 KZN88810.1 - 3.8e-30 104.8 1.3 6.1e-30 104.2 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN88810.1 - 0.00086 19.4 17.6 0.0017 18.4 17.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN88811.1 - 1.6e-10 40.5 0.0 2.8e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain UDG PF03167.19 KZN88812.1 - 5.6e-25 88.1 0.1 1.1e-24 87.2 0.1 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily BDHCT_assoc PF16204.5 KZN88812.1 - 0.75 9.4 7.1 0.3 10.8 1.9 2.2 2 0 0 2 2 2 0 BDHCT-box associated domain on Bloom syndrome protein Thioredoxin PF00085.20 KZN88813.1 - 2.9e-63 210.3 3.2 8.8e-32 109.2 0.1 4.2 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 KZN88813.1 - 1.1e-46 159.1 5.1 2.3e-35 122.1 0.4 3.5 3 1 1 4 4 4 3 Thioredoxin-like domain Calsequestrin PF01216.17 KZN88813.1 - 7.4e-13 48.3 1.4 1.3e-12 47.5 0.7 1.7 2 0 0 2 2 2 1 Calsequestrin AhpC-TSA PF00578.21 KZN88813.1 - 1.1e-08 35.0 1.9 0.00011 22.1 0.0 3.4 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.10 KZN88813.1 - 2.4e-08 33.8 3.0 0.041 13.6 0.1 3.4 3 0 0 3 3 3 3 Redoxin Thioredoxin_2 PF13098.6 KZN88813.1 - 5.5e-08 33.2 2.4 0.011 16.2 0.2 3.5 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KZN88813.1 - 6.1e-08 32.7 0.1 0.012 15.8 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KZN88813.1 - 4.1e-07 30.2 0.1 0.041 14.2 0.0 3.9 3 1 1 4 4 4 2 Thioredoxin-like OST3_OST6 PF04756.13 KZN88813.1 - 9.5e-05 21.9 0.1 0.57 9.5 0.0 3.3 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_4 PF13462.6 KZN88813.1 - 9.6 6.3 7.4 23 5.1 0.0 3.5 5 0 0 5 5 5 0 Thioredoxin ATG22 PF11700.8 KZN88814.1 - 1.2e-215 716.7 7.4 1.3e-215 716.5 7.4 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KZN88814.1 - 1.9e-08 33.6 19.9 1.9e-08 33.6 19.9 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily Med14 PF08638.11 KZN88815.1 - 1.4e-65 220.3 0.0 2.2e-65 219.7 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 DNA_pol_E_B PF04042.16 KZN88816.1 - 9.9e-50 168.8 0.0 1.3e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B SHNi-TPR PF10516.9 KZN88817.1 - 4.9e-14 51.5 0.2 1.6e-13 49.9 0.2 1.9 1 0 0 1 1 1 1 SHNi-TPR TPR_12 PF13424.6 KZN88817.1 - 0.00023 21.4 4.3 0.19 12.1 1.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KZN88817.1 - 0.0014 18.2 1.0 6.3 6.6 0.2 4.0 4 0 0 4 4 4 1 TPR repeat Snapin_Pallidin PF14712.6 KZN88817.1 - 0.92 10.0 6.6 4.2 7.9 2.0 3.1 3 0 0 3 3 3 0 Snapin/Pallidin TPR_2 PF07719.17 KZN88817.1 - 0.98 9.7 4.9 35 4.8 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat CCDC-167 PF15188.6 KZN88817.1 - 2.2 8.7 11.0 0.069 13.5 3.8 2.2 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Yippee-Mis18 PF03226.14 KZN88818.1 - 3.6e-24 85.0 0.1 5.7e-24 84.3 0.1 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF678 PF05077.12 KZN88818.1 - 0.012 15.8 0.1 2.7 8.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF678) RIG-I_C-RD PF11648.8 KZN88818.1 - 0.019 15.2 0.7 0.39 11.0 0.0 2.2 2 0 0 2 2 2 0 C-terminal domain of RIG-I Transp_Tc5_C PF04236.15 KZN88818.1 - 0.067 13.6 0.5 2.9 8.3 0.0 2.7 3 0 0 3 3 3 0 Tc5 transposase C-terminal domain DWNN PF08783.11 KZN88819.1 - 4.7e-33 113.3 0.1 4.7e-33 113.3 0.1 2.2 3 0 0 3 3 3 1 DWNN domain zf-CCHC_2 PF13696.6 KZN88819.1 - 3.6e-08 33.1 5.0 6.4e-08 32.3 5.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KZN88819.1 - 0.002 18.1 0.7 0.0041 17.1 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 KZN88819.1 - 0.0024 17.7 8.2 0.005 16.7 8.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KZN88819.1 - 0.14 12.0 2.8 0.33 10.8 2.8 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.6 KZN88819.1 - 0.31 11.4 6.6 0.69 10.3 6.6 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 KZN88819.1 - 0.4 10.5 6.0 0.97 9.3 6.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 KZN88819.1 - 3.6 7.5 8.2 7.8 6.5 8.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KZN88819.1 - 4 7.7 9.3 11 6.3 9.3 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KZN88819.1 - 8 6.5 11.6 0.48 10.4 5.4 2.1 2 0 0 2 2 2 0 zinc-RING finger domain His_biosynth PF00977.21 KZN88820.1 - 6.3e-45 153.4 0.3 1.5e-44 152.2 0.3 1.7 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 KZN88820.1 - 1.7e-23 83.4 0.0 2.7e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 KZN88820.1 - 7e-11 42.3 0.0 6.2e-09 36.0 0.0 2.2 2 0 0 2 2 2 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KZN88820.1 - 3e-09 36.8 0.0 6e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 KZN88820.1 - 0.0023 17.7 0.0 0.0078 16.0 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 KZN88820.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family dCMP_cyt_deam_1 PF00383.23 KZN88821.1 - 4.9e-28 97.0 0.9 7.9e-28 96.3 0.9 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KZN88821.1 - 9.3e-12 44.9 0.1 1.6e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 KZN88821.1 - 0.0023 18.5 0.0 0.01 16.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain CoaE PF01121.20 KZN88821.1 - 0.0081 15.8 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Dephospho-CoA kinase ATG7_N PF16420.5 KZN88822.1 - 1.6e-112 376.1 0.0 2e-112 375.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KZN88822.1 - 1.9e-44 151.9 0.0 3.6e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 KZN88822.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FtsJ PF01728.19 KZN88823.1 - 2.4e-52 177.6 0.0 3.1e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 KZN88823.1 - 0.00052 19.9 0.0 0.00093 19.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN88823.1 - 0.015 15.1 0.0 0.26 11.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 KZN88823.1 - 0.018 15.7 0.0 0.24 12.1 0.0 2.6 3 0 0 3 3 3 0 Methyltransferase domain Filament PF00038.21 KZN88824.1 - 0.015 14.9 34.3 0.071 12.7 34.3 2.5 1 1 0 1 1 1 0 Intermediate filament protein Golgin_A5 PF09787.9 KZN88824.1 - 0.4 10.1 33.5 4.1 6.8 17.3 2.6 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF4600 PF15372.6 KZN88824.1 - 0.56 10.7 19.2 1.2 9.5 13.2 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) Leu_zip PF15294.6 KZN88824.1 - 0.57 9.6 28.9 0.27 10.7 8.5 2.6 1 1 1 2 2 2 0 Leucine zipper Cep57_CLD_2 PF14197.6 KZN88824.1 - 0.67 10.1 33.0 6.3 7.0 8.5 5.2 3 2 0 3 3 3 0 Centrosome localisation domain of PPC89 GAS PF13851.6 KZN88824.1 - 5.2 6.4 33.5 0.017 14.5 12.5 3.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 KZN88824.1 - 7.2 6.7 39.2 3.9 7.5 21.9 3.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein OST3_OST6 PF04756.13 KZN88825.1 - 8.7e-105 350.3 0.0 1e-104 350.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HXXEE PF13787.6 KZN88825.1 - 0.068 14.0 2.5 0.11 13.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif Rft-1 PF04506.13 KZN88826.1 - 4e-140 468.0 15.2 4.8e-140 467.7 15.2 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.17 KZN88826.1 - 3.1e-07 30.1 13.6 3.1e-07 30.1 13.6 2.6 2 2 1 3 3 3 1 Polysaccharide biosynthesis protein DEAD PF00270.29 KZN88827.1 - 4.8e-49 166.5 0.0 9.2e-49 165.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KZN88827.1 - 2.4e-32 111.6 0.1 3.6e-29 101.3 0.0 2.5 2 1 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KZN88827.1 - 4.5e-09 36.5 0.0 8.9e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KZN88827.1 - 0.00093 18.1 0.0 0.51 9.1 0.0 2.3 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ERCC3_RAD25_C PF16203.5 KZN88827.1 - 0.0021 17.3 0.1 0.0049 16.1 0.0 1.6 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 KZN88827.1 - 0.0095 15.3 0.6 0.18 11.1 0.0 2.5 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Rep_fac-A_C PF08646.10 KZN88828.1 - 2.8e-55 186.1 4.9 1.7e-53 180.3 0.4 2.3 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KZN88828.1 - 6.9e-38 128.5 0.3 3.7e-37 126.2 0.2 2.1 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 KZN88828.1 - 8.7e-23 80.3 0.5 1.8e-22 79.3 0.1 1.8 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KZN88828.1 - 2.8e-13 49.7 0.0 1.3e-08 34.7 0.0 3.7 3 1 0 3 3 3 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 KZN88828.1 - 0.00063 19.5 0.0 0.016 14.9 0.0 2.8 2 1 0 2 2 2 1 Cell division control protein 24, OB domain 3 UCH PF00443.29 KZN88829.1 - 5.2e-41 140.8 0.0 7.2e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 KZN88829.1 - 7.9e-25 86.4 1.4 3.6e-23 81.1 0.1 2.7 2 0 0 2 2 2 1 Variant UBP zinc finger zf-UBP PF02148.19 KZN88829.1 - 3.1e-21 75.5 21.3 1.6e-18 66.8 2.5 3.4 4 0 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 KZN88829.1 - 4.7e-19 67.9 1.1 1.3e-10 40.9 0.0 2.8 3 0 0 3 3 3 2 UBA/TS-N domain UCH_1 PF13423.6 KZN88829.1 - 7.7e-18 65.1 0.9 3.3e-16 59.8 0.8 3.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 KZN88829.1 - 0.056 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Prim_Zn_Ribbon PF08273.12 KZN88829.1 - 0.44 10.9 0.1 0.44 10.9 0.1 4.9 5 0 0 5 5 5 0 Zinc-binding domain of primase-helicase zf-RING_UBOX PF13445.6 KZN88829.1 - 2 8.5 9.0 7 6.8 0.0 3.6 3 0 0 3 3 3 0 RING-type zinc-finger RNA_pol_N PF01194.17 KZN88830.1 - 1.5e-30 105.2 1.4 1.8e-30 105.0 1.4 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit WD40 PF00400.32 KZN88831.1 - 0.029 15.2 0.3 0.029 15.2 0.3 6.0 7 0 0 7 7 7 0 WD domain, G-beta repeat Kelch_6 PF13964.6 KZN88831.1 - 0.06 13.7 1.1 0.81 10.1 0.1 3.4 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.15 KZN88831.1 - 0.074 13.1 0.9 0.9 9.6 0.3 3.1 2 0 0 2 2 2 0 Kelch motif Clr5 PF14420.6 KZN88832.1 - 4.9e-17 61.9 0.6 4.9e-17 61.9 0.6 2.2 2 0 0 2 2 2 1 Clr5 domain YozE_SAM_like PF06855.12 KZN88832.1 - 0.028 14.6 0.3 11 6.2 0.0 2.7 2 0 0 2 2 2 0 YozE SAM-like fold DUF2407_C PF13373.6 KZN88832.1 - 0.096 12.9 0.1 0.26 11.5 0.1 1.7 1 0 0 1 1 1 0 DUF2407 C-terminal domain Het-C PF07217.11 KZN88834.1 - 1.2e-246 819.7 0.0 1.5e-246 819.3 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Laminin_I PF06008.14 KZN88834.1 - 0.12 12.1 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Laminin Domain I FAD-oxidase_C PF02913.19 KZN88835.1 - 2e-59 201.2 0.1 5.1e-59 199.9 0.1 1.6 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KZN88835.1 - 4.1e-36 123.8 0.0 8.9e-36 122.7 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain ADH_N PF08240.12 KZN88836.1 - 7.2e-35 119.2 0.2 1.5e-34 118.1 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN88836.1 - 6.4e-22 77.9 0.3 1.1e-21 77.2 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KZN88836.1 - 7.9e-08 32.0 0.4 1.5e-07 31.2 0.4 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 KZN88836.1 - 0.00031 20.4 0.0 0.00051 19.7 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 KZN88836.1 - 0.00059 19.2 0.9 0.00096 18.5 0.9 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KZN88836.1 - 0.0013 19.8 0.0 0.0026 18.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FtsJ PF01728.19 KZN88836.1 - 0.007 16.5 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase 2-Hacid_dh_C PF02826.19 KZN88836.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KZN88836.1 - 0.013 16.2 0.1 0.028 15.1 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox_2 PF07992.14 KZN88836.1 - 0.015 14.5 0.5 0.03 13.6 0.5 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PrmA PF06325.13 KZN88836.1 - 0.12 11.8 0.3 0.17 11.3 0.3 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ras PF00071.22 KZN88837.1 - 1.2e-39 135.6 0.0 1.8e-39 134.9 0.0 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KZN88837.1 - 6.1e-27 94.2 0.0 1e-26 93.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KZN88837.1 - 1.1e-10 41.2 0.0 1.3e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KZN88837.1 - 0.0021 17.5 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KZN88837.1 - 0.0044 17.1 0.0 0.007 16.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KZN88837.1 - 0.024 14.5 0.0 0.35 10.8 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase SRPRB PF09439.10 KZN88837.1 - 0.044 13.2 0.0 0.07 12.6 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 KZN88837.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KZN88837.1 - 0.1 13.0 0.2 0.42 11.0 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KZN88837.1 - 0.12 12.8 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter FAM199X PF15814.5 KZN88838.1 - 0.75 8.8 4.7 1.2 8.1 4.7 1.2 1 0 0 1 1 1 0 Protein family FAM199X zf-Mss51 PF13824.6 KZN88840.1 - 5.2e-29 100.1 7.2 1.2e-28 99.0 7.2 1.7 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KZN88840.1 - 0.029 14.4 0.3 0.029 14.4 0.3 1.8 2 0 0 2 2 2 0 MYND finger DUF3011 PF11218.8 KZN88840.1 - 0.032 14.2 0.1 0.056 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3011) zf-HIT PF04438.16 KZN88840.1 - 0.41 10.6 2.3 2 8.4 0.4 2.4 2 0 0 2 2 2 0 HIT zinc finger Oxysterol_BP PF01237.18 KZN88841.1 - 6e-135 449.9 0.4 6.4e-134 446.5 0.0 2.1 2 0 0 2 2 2 1 Oxysterol-binding protein ATP12 PF07542.11 KZN88841.1 - 1.6e-43 147.9 0.4 3.9e-43 146.6 0.4 1.7 1 0 0 1 1 1 1 ATP12 chaperone protein Ank_5 PF13857.6 KZN88841.1 - 1.4e-13 50.8 0.2 3e-08 33.8 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KZN88841.1 - 1.7e-12 47.7 0.0 3.6e-08 33.9 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KZN88841.1 - 4.5e-11 42.7 0.0 0.015 15.7 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat PH PF00169.29 KZN88841.1 - 9.2e-11 42.2 0.4 2.1e-10 41.0 0.4 1.7 1 0 0 1 1 1 1 PH domain Ank_3 PF13606.6 KZN88841.1 - 2.5e-09 36.6 0.0 0.0071 16.8 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KZN88841.1 - 3.3e-08 33.9 0.1 2.6e-05 24.7 0.0 4.1 2 1 2 4 4 4 1 Ankyrin repeats (many copies) PH_8 PF15409.6 KZN88841.1 - 1.5e-06 28.4 0.9 3.6e-06 27.2 0.9 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KZN88841.1 - 3.8e-05 24.1 2.1 3.8e-05 24.1 2.1 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain Raptor_N PF14538.6 KZN88842.1 - 0.00078 19.4 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain Peptidase_C14 PF00656.22 KZN88842.1 - 0.0036 17.3 0.0 0.0073 16.3 0.0 1.5 1 1 0 1 1 1 1 Caspase domain MA-Mit PF09245.10 KZN88842.1 - 0.013 15.0 0.1 0.022 14.3 0.1 1.3 1 0 0 1 1 1 0 Mycoplasma arthritidis-derived mitogen Glyco_tranf_2_3 PF13641.6 KZN88843.1 - 1.5e-30 106.8 0.1 1.9e-30 106.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KZN88843.1 - 1.4e-06 28.2 0.0 2.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KZN88843.1 - 2.9e-06 26.9 0.1 0.0015 18.1 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 21 PagL PF09411.10 KZN88844.1 - 0.062 13.4 0.1 0.13 12.4 0.1 1.6 1 1 0 1 1 1 0 Lipid A 3-O-deacylase (PagL) DUF3824 PF12868.7 KZN88844.1 - 0.29 11.8 7.8 0.42 11.3 7.8 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) ADH_zinc_N PF00107.26 KZN88846.1 - 4.8e-28 97.7 1.9 8.5e-28 96.9 1.9 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KZN88846.1 - 3.6e-09 37.8 0.0 6.7e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KZN88846.1 - 5.6e-07 29.4 0.0 4.2e-06 26.6 0.0 2.5 3 1 1 4 4 4 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KZN88846.1 - 0.0068 16.7 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 KZN88846.1 - 0.0086 15.4 1.5 0.017 14.5 1.5 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Clr5 PF14420.6 KZN88847.1 - 4.7e-12 45.9 1.6 8.1e-12 45.2 1.6 1.4 1 0 0 1 1 1 1 Clr5 domain SNF2_N PF00176.23 KZN88848.1 - 7.6e-64 215.6 0.2 1.3e-63 214.8 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KZN88848.1 - 4.3e-19 68.9 0.0 1.4e-18 67.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KZN88848.1 - 1.7e-10 41.2 0.0 3.3e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HSA PF07529.13 KZN88848.1 - 2.3e-07 31.0 8.1 2.3e-07 31.0 8.1 2.4 2 0 0 2 2 2 1 HSA DEAD PF00270.29 KZN88848.1 - 0.00021 21.1 0.0 0.00052 19.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 KZN88848.1 - 0.024 14.3 0.1 0.077 12.6 0.0 1.9 2 0 0 2 2 2 0 DEAD_2 NDUF_B8 PF05821.11 KZN88849.1 - 4.3e-08 33.2 1.4 7.4e-08 32.4 1.4 1.5 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Membr_traf_MHD PF10540.9 KZN88850.1 - 7.1e-21 74.9 0.9 1.5e-10 41.4 0.7 3.5 2 1 1 3 3 3 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KZN88850.1 - 6.4e-15 55.3 0.0 1.4e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain Pribosyltran PF00156.27 KZN88852.1 - 4.5e-17 62.0 0.0 6.1e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Thi4 PF01946.17 KZN88852.1 - 0.15 11.3 0.2 0.21 10.8 0.2 1.2 1 0 0 1 1 1 0 Thi4 family AIG2_2 PF13772.6 KZN88853.1 - 0.0028 18.0 0.0 0.013 15.9 0.0 2.0 2 0 0 2 2 2 1 AIG2-like family GGACT PF06094.12 KZN88853.1 - 0.034 14.7 0.0 0.068 13.8 0.0 1.5 1 1 0 1 1 1 0 Gamma-glutamyl cyclotransferase, AIG2-like F-box-like PF12937.7 KZN88854.1 - 0.00093 19.0 1.3 0.18 11.7 0.0 3.2 3 0 0 3 3 3 2 F-box-like F-box PF00646.33 KZN88854.1 - 0.05 13.5 0.0 2 8.4 0.0 2.4 2 0 0 2 2 2 0 F-box domain AP_endonuc_2 PF01261.24 KZN88855.1 - 1.3e-27 96.6 0.0 1.9e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Glyco_hydro_47 PF01532.20 KZN88856.1 - 7.9e-117 390.9 0.0 1e-116 390.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 WD40 PF00400.32 KZN88858.1 - 3e-40 135.4 5.7 2.2e-06 28.3 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN88858.1 - 1.7e-11 44.2 0.1 0.028 14.7 0.0 5.3 2 2 5 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KZN88858.1 - 0.01 14.6 0.4 0.84 8.3 0.1 2.5 1 1 1 2 2 2 0 Nup133 N terminal like WD40_like PF17005.5 KZN88858.1 - 0.024 14.0 0.0 2.8 7.2 0.1 3.0 2 1 1 3 3 3 0 WD40-like domain TRAPP PF04051.16 KZN88859.1 - 1.3e-35 122.2 0.0 2.3e-35 121.5 0.0 1.4 2 0 0 2 2 2 1 Transport protein particle (TRAPP) component PNGaseA PF12222.8 KZN88859.1 - 0.011 14.7 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF4250 PF14056.6 KZN88859.1 - 0.091 12.7 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) LisH PF08513.11 KZN88860.1 - 4.5e-05 23.3 0.3 4.5e-05 23.3 0.3 1.8 2 0 0 2 2 2 1 LisH Attacin_N PF03768.15 KZN88861.1 - 0.14 12.3 7.6 18 5.5 0.2 4.0 1 1 2 3 3 3 0 Attacin, N-terminal region RRM_1 PF00076.22 KZN88863.1 - 6.7e-46 154.0 0.0 7.6e-17 60.9 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KZN88863.1 - 7.7e-06 25.8 0.1 0.0015 18.4 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KZN88863.1 - 0.0001 22.1 0.0 0.057 13.3 0.0 2.9 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KZN88863.1 - 0.00013 21.9 0.0 0.0012 18.8 0.0 2.3 3 0 0 3 3 3 1 RNA binding motif RRM_7 PF16367.5 KZN88863.1 - 0.00063 19.8 0.1 0.051 13.7 0.0 2.8 3 1 0 3 3 3 1 RNA recognition motif RRM_5 PF13893.6 KZN88863.1 - 0.0094 15.5 0.0 0.068 12.8 0.0 2.3 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KZN88863.1 - 0.11 12.8 0.1 13 5.9 0.0 3.4 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter UPF0154 PF03672.13 KZN88863.1 - 0.21 11.6 1.6 0.43 10.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) TFB6 PF17110.5 KZN88864.1 - 4.4e-34 117.7 0.0 7.1e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH RRM_Rrp7 PF17799.1 KZN88865.1 - 1.3e-29 103.1 0.0 2.1e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRP7 PF12923.7 KZN88865.1 - 3.6e-26 91.6 9.9 3.6e-26 91.6 9.9 2.0 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_1 PF00076.22 KZN88865.1 - 0.077 12.8 0.0 6.6 6.6 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dak1_2 PF13684.6 KZN88865.1 - 0.18 10.9 1.0 0.76 8.8 0.0 2.1 2 1 0 2 2 2 0 Dihydroxyacetone kinase family Rad51 PF08423.11 KZN88866.1 - 3.8e-111 370.4 0.0 4.8e-111 370.1 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KZN88866.1 - 7.6e-11 42.0 0.0 9.9e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 KZN88866.1 - 3e-08 34.2 1.7 6.6e-08 33.0 0.6 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 KZN88866.1 - 1.9e-07 30.7 0.0 4.7e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 KZN88866.1 - 7.5e-05 22.4 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 KZN88866.1 - 0.077 12.3 0.0 1.2 8.4 0.0 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain zf-CCHC PF00098.23 KZN88867.1 - 1.9e-36 122.5 41.8 1.9e-07 30.8 3.4 5.7 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_3 PF13917.6 KZN88867.1 - 1.2e-07 31.6 22.2 0.028 14.4 0.1 5.1 4 1 1 5 5 5 4 Zinc knuckle zf-CCHC_4 PF14392.6 KZN88867.1 - 3.1e-05 23.6 30.3 0.036 13.8 0.4 5.8 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_5 PF14787.6 KZN88867.1 - 0.0001 21.9 28.7 0.017 14.8 0.8 5.1 3 1 2 5 5 5 4 GAG-polyprotein viral zinc-finger UDPGP PF01704.18 KZN88868.1 - 3.2e-59 200.6 0.0 3.9e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Pro_isomerase PF00160.21 KZN88869.1 - 2.7e-37 128.5 0.0 4e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KZN88869.1 - 1e-14 54.1 0.0 2e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.18 KZN88870.1 - 1e-08 35.2 6.5 1.8e-08 34.3 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S24e PF01282.19 KZN88871.1 - 1.8e-35 120.7 0.1 3.3e-35 119.9 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S24e RRXRR PF14239.6 KZN88871.1 - 0.0073 16.2 1.3 0.01 15.7 1.2 1.4 1 1 0 1 1 1 1 RRXRR protein Methyltransf_16 PF10294.9 KZN88872.1 - 3.8e-16 59.3 0.0 2.2e-15 56.8 0.0 1.9 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KZN88872.1 - 0.013 16.2 0.1 0.031 15.0 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KZN88872.1 - 0.016 14.7 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 KZN88872.1 - 0.025 14.0 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KZN88872.1 - 0.033 14.0 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KZN88872.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain HAP1_N PF04849.13 KZN88873.1 - 0.0018 17.6 4.2 0.0018 17.6 4.2 3.2 2 1 1 3 3 3 2 HAP1 N-terminal conserved region Fib_alpha PF08702.10 KZN88873.1 - 0.0027 17.9 5.1 0.0027 17.9 5.1 3.3 1 1 2 3 3 3 1 Fibrinogen alpha/beta chain family DivIVA PF05103.13 KZN88873.1 - 0.05 13.7 29.6 3.2 7.8 13.7 3.9 2 1 2 4 4 4 0 DivIVA protein IKKbetaNEMObind PF12179.8 KZN88873.1 - 0.079 13.0 0.4 1.2 9.2 0.1 2.9 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain DUF948 PF06103.11 KZN88873.1 - 0.4 11.0 10.3 4 7.8 1.2 3.6 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Fez1 PF06818.15 KZN88873.1 - 0.62 10.5 33.5 0.084 13.3 23.3 2.8 2 1 1 3 3 3 0 Fez1 Mod_r PF07200.13 KZN88873.1 - 0.94 9.6 30.0 0.26 11.4 16.5 3.4 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DivIC PF04977.15 KZN88873.1 - 1.7 8.4 26.4 0.27 11.0 5.3 3.7 3 1 1 4 4 4 0 Septum formation initiator EzrA PF06160.12 KZN88873.1 - 2.5 6.2 21.5 0.32 9.1 17.0 1.8 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA YabA PF06156.13 KZN88873.1 - 7.5 7.3 23.7 11 6.8 5.5 3.8 1 1 2 4 4 4 0 Initiation control protein YabA CLTH PF10607.9 KZN88874.1 - 2.2e-31 108.7 0.0 4.1e-31 107.9 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 KZN88874.1 - 1.2e-25 90.0 0.2 1.8e-25 89.4 0.2 1.3 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 KZN88874.1 - 0.001 18.9 0.2 0.0037 17.2 0.0 2.1 2 0 0 2 2 2 1 LisH INO80_Ies4 PF08193.11 KZN88875.1 - 1.1e-66 225.4 18.0 1.3e-66 225.1 18.0 1.1 1 0 0 1 1 1 1 INO80 complex subunit Ies4 Metaviral_G PF09595.10 KZN88875.1 - 0.18 11.9 13.6 0.091 12.8 6.7 2.2 2 0 0 2 2 2 0 Metaviral_G glycoprotein DnaJ PF00226.31 KZN88876.1 - 7.5e-16 58.0 0.1 1.3e-15 57.3 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain RPA43_OB PF17875.1 KZN88877.1 - 1.1e-39 135.9 0.0 1.1e-39 135.9 0.0 2.8 3 0 0 3 3 3 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 KZN88877.1 - 5.1e-07 30.0 0.0 1.3e-06 28.6 0.0 1.8 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DDHD PF02862.17 KZN88877.1 - 0.2 11.8 6.0 2.5 8.2 4.9 2.2 2 0 0 2 2 2 0 DDHD domain AP3D1 PF06375.11 KZN88877.1 - 1.2 9.4 28.0 0.43 10.8 18.8 2.5 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 DUF4770 PF15994.5 KZN88877.1 - 6.5 7.0 14.7 7.8 6.7 9.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) SR-25 PF10500.9 KZN88877.1 - 7.3 6.1 33.8 5.2 6.6 21.1 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RPN2_C PF18004.1 KZN88877.1 - 9.8 6.1 27.7 0.98 9.3 18.8 2.3 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Pyr_redox_2 PF07992.14 KZN88878.1 - 1.5e-46 159.0 0.0 2.2e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KZN88878.1 - 1.7e-17 63.2 0.0 4.6e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 KZN88878.1 - 1.6e-12 47.8 2.4 2.2e-11 44.2 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DUF1188 PF06690.11 KZN88878.1 - 0.00052 19.6 0.1 0.0018 17.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1188) Reductase_C PF14759.6 KZN88878.1 - 0.00064 20.2 0.0 0.003 18.1 0.0 2.1 2 0 0 2 2 2 1 Reductase C-terminal NAD_binding_9 PF13454.6 KZN88878.1 - 0.0024 17.9 0.3 3.9 7.5 0.0 3.1 3 0 0 3 3 3 2 FAD-NAD(P)-binding TrkA_N PF02254.18 KZN88878.1 - 0.052 13.8 0.4 2.4 8.4 0.0 2.8 2 1 1 3 3 3 0 TrkA-N domain Arrestin_N PF00339.29 KZN88880.1 - 1.8e-12 47.5 0.1 3.6e-10 40.1 0.1 3.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain UL42 PF17638.2 KZN88880.1 - 1.8 8.6 8.8 0.067 13.2 1.5 2.4 2 0 0 2 2 2 0 HCMV UL42 PET117 PF15786.5 KZN88882.1 - 9.4e-23 80.3 0.8 1.1e-22 80.0 0.8 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial Cep57_CLD PF14073.6 KZN88882.1 - 0.0053 16.8 0.3 0.0066 16.5 0.3 1.1 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 DASH_Duo1 PF08651.10 KZN88883.1 - 0.024 14.4 1.3 0.14 11.9 0.0 2.5 2 1 0 3 3 3 0 DASH complex subunit Duo1 DUF1664 PF07889.12 KZN88883.1 - 0.035 14.1 0.1 0.048 13.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) HR1 PF02185.16 KZN88883.1 - 0.064 13.4 0.6 0.12 12.5 0.6 1.4 1 0 0 1 1 1 0 Hr1 repeat Aldo_ket_red PF00248.21 KZN88884.1 - 1.6e-64 218.0 0.0 2.3e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family SBD_N PF07005.11 KZN88884.1 - 1.2e-61 208.4 0.2 6.1e-61 206.1 0.0 1.9 2 0 0 2 2 2 1 Sugar-binding N-terminal domain NBD_C PF17042.5 KZN88884.1 - 6.7e-37 127.6 0.0 1.5e-36 126.5 0.0 1.6 1 0 0 1 1 1 1 Nucleotide-binding C-terminal domain FMN_dh PF01070.18 KZN88885.1 - 5.1e-112 374.3 0.0 6.1e-112 374.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KZN88885.1 - 2.8e-19 69.0 0.0 5.7e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KZN88885.1 - 2.9e-06 26.7 0.3 1.6e-05 24.2 0.0 1.9 1 1 1 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.25 KZN88885.1 - 8.9e-05 21.6 0.7 0.00024 20.2 0.7 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KZN88885.1 - 0.00088 18.6 0.6 0.055 12.8 0.1 2.5 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KZN88885.1 - 0.025 14.1 0.0 0.12 11.8 0.0 2.0 1 1 1 2 2 2 0 Histidine biosynthesis protein NMO PF03060.15 KZN88885.1 - 0.034 13.5 0.9 0.053 12.9 0.4 1.4 1 1 0 1 1 1 0 Nitronate monooxygenase IGPS PF00218.21 KZN88885.1 - 0.21 10.7 0.0 1.8 7.6 0.0 2.1 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Epimerase PF01370.21 KZN88886.1 - 2.1e-16 60.1 0.0 2.7e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KZN88886.1 - 4.3e-11 42.8 0.0 7e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KZN88886.1 - 5.7e-09 35.4 0.0 9.3e-09 34.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KZN88886.1 - 1.8e-06 27.3 0.0 9.2e-06 25.0 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 KZN88886.1 - 5.2e-06 26.5 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KZN88886.1 - 1.3e-05 24.5 0.0 0.082 12.1 0.0 2.5 2 1 0 2 2 2 2 Male sterility protein adh_short PF00106.25 KZN88886.1 - 0.00021 20.8 0.0 0.00045 19.7 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Ldh_1_N PF00056.23 KZN88886.1 - 0.0031 17.6 0.0 0.0054 16.8 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KZN88886.1 - 0.057 12.5 0.0 0.25 10.4 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DapB_N PF01113.20 KZN88886.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Zn_clus PF00172.18 KZN88887.1 - 5.3e-09 36.1 7.0 8.9e-09 35.3 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHDPS PF00701.22 KZN88888.1 - 5.7e-43 146.7 0.0 7.3e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family BNR_2 PF13088.6 KZN88889.1 - 4.1e-77 259.2 0.2 4.8e-77 259.0 0.2 1.0 1 0 0 1 1 1 1 BNR repeat-like domain BNR_4 PF15892.5 KZN88889.1 - 0.00013 21.4 0.0 0.17 11.2 0.0 3.1 2 1 1 3 3 3 2 BNR repeat-containing family member Sortilin-Vps10 PF15902.5 KZN88889.1 - 0.0019 17.1 0.5 2.5 6.8 0.1 3.1 2 2 0 2 2 2 2 Sortilin, neurotensin receptor 3, PSII_BNR PF14870.6 KZN88889.1 - 0.0028 16.9 0.4 0.074 12.3 0.1 2.5 3 0 0 3 3 3 1 Photosynthesis system II assembly factor YCF48 BNR PF02012.20 KZN88889.1 - 0.032 14.2 26.9 0.86 9.9 0.2 5.8 6 0 0 6 6 6 0 BNR/Asp-box repeat Sugar_tr PF00083.24 KZN88890.1 - 3.1e-104 349.4 12.5 3.8e-104 349.1 12.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN88890.1 - 2.2e-25 89.3 18.0 2.2e-25 89.3 18.0 1.9 1 1 2 3 3 3 1 Major Facilitator Superfamily Aldo_ket_red PF00248.21 KZN88891.1 - 9.3e-47 159.6 0.0 3e-45 154.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family IDO PF01231.18 KZN88892.1 - 8.7e-33 113.7 0.0 1.3e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase TPR_2 PF07719.17 KZN88893.1 - 3.7e-11 42.2 6.8 0.0087 16.1 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KZN88893.1 - 8.9e-08 32.5 1.1 0.0072 16.8 0.3 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat F-box PF00646.33 KZN88893.1 - 7.7e-07 28.8 0.1 2.6e-06 27.2 0.1 2.0 1 0 0 1 1 1 1 F-box domain TPR_1 PF00515.28 KZN88893.1 - 4.3e-06 26.3 6.9 0.7 9.8 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 KZN88893.1 - 7.4e-06 26.4 2.7 0.3 12.0 0.0 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KZN88893.1 - 1.3e-05 25.3 3.7 0.12 12.7 0.2 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KZN88893.1 - 5e-05 23.0 0.3 0.19 11.9 0.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat LRR_4 PF12799.7 KZN88893.1 - 0.00015 22.0 11.6 0.9 10.1 0.0 7.0 7 2 1 8 8 8 1 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KZN88893.1 - 0.0011 18.8 0.1 0.0026 17.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like TPR_9 PF13371.6 KZN88893.1 - 0.0011 19.0 1.7 0.12 12.6 0.4 2.6 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KZN88893.1 - 0.0018 18.9 4.0 0.18 12.5 1.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KZN88893.1 - 0.0068 16.7 2.2 1.3 9.6 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat LRR_8 PF13855.6 KZN88893.1 - 0.011 15.5 0.5 1.3 8.9 0.0 4.3 5 0 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.6 KZN88893.1 - 0.015 15.3 1.2 65 4.0 0.0 5.3 5 0 0 5 5 5 0 Leucine Rich repeat TPR_11 PF13414.6 KZN88893.1 - 0.047 13.4 2.7 0.19 11.4 0.2 2.7 2 1 1 3 3 3 0 TPR repeat TPR_8 PF13181.6 KZN88893.1 - 0.062 13.5 3.7 2.7 8.4 0.1 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 KZN88893.1 - 0.32 10.7 1.7 0.86 9.3 1.7 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 KZN88893.1 - 0.42 10.6 4.7 20 5.2 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_1 PF00560.33 KZN88893.1 - 0.56 11.0 6.4 70 4.6 0.0 5.6 5 1 0 5 5 4 0 Leucine Rich Repeat TPR_6 PF13174.6 KZN88893.1 - 5.8 7.8 7.8 6.9 7.5 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ADIP PF11559.8 KZN88894.1 - 9e-43 146.0 9.5 9e-43 146.0 9.5 2.7 4 0 0 4 4 4 1 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 KZN88894.1 - 0.002 17.6 9.4 0.002 17.6 9.4 2.6 2 0 0 2 2 2 1 Golgin subfamily A member 5 DUF724 PF05266.14 KZN88894.1 - 0.003 17.4 8.5 0.003 17.4 8.5 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF724) TTRAP PF14203.6 KZN88894.1 - 0.025 14.6 0.3 0.15 12.1 0.3 2.3 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein RepA_C PF04796.12 KZN88894.1 - 0.039 14.0 0.6 0.085 12.9 0.6 1.5 1 0 0 1 1 1 0 Plasmid encoded RepA protein TMPIT PF07851.13 KZN88894.1 - 0.86 8.8 6.3 2.1 7.5 6.3 1.7 1 0 0 1 1 1 0 TMPIT-like protein FlaC_arch PF05377.11 KZN88894.1 - 1.2 9.6 4.8 4.6 7.7 0.7 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF465 PF04325.13 KZN88894.1 - 4.8 7.3 7.6 6.6 6.9 0.2 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF465) PKcGMP_CC PF16808.5 KZN88894.1 - 7 6.6 9.3 12 5.8 0.2 3.7 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ADH_N PF08240.12 KZN88895.1 - 2.5e-22 78.8 0.8 4.1e-22 78.1 0.8 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN88895.1 - 5e-17 62.1 0.2 9.7e-17 61.2 0.1 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KZN88895.1 - 2.1e-06 28.8 0.0 3.3e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KZN88895.1 - 0.029 13.7 1.1 0.052 12.9 1.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RTA1 PF04479.13 KZN88896.1 - 1.5e-63 214.1 11.7 1.5e-63 214.1 11.7 1.8 2 0 0 2 2 2 1 RTA1 like protein Zn_clus PF00172.18 KZN88897.1 - 1e-07 31.9 10.9 1.7e-07 31.3 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KZN88897.1 - 1.3e-07 30.8 0.0 1.6e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain 7TMR-DISMED2 PF07696.11 KZN88898.1 - 0.057 13.5 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 7TMR-DISM extracellular 2 Nucleopor_Nup85 PF07575.13 KZN88899.1 - 2.2e-27 95.9 0.0 2.5e-20 72.6 0.0 2.7 2 1 0 2 2 2 2 Nup85 Nucleoporin Pkinase PF00069.25 KZN88902.1 - 2.7e-17 63.0 0.0 3.8e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN88902.1 - 2.5e-15 56.5 0.0 3.5e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Metallophos_3 PF14582.6 KZN88902.1 - 0.0078 15.6 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily DUF4624 PF15417.6 KZN88902.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4624) Fungal_trans PF04082.18 KZN88904.1 - 1.4e-10 40.7 0.0 2.6e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN88904.1 - 8.4e-09 35.4 7.9 1.3e-08 34.8 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phage_tail_2 PF06199.11 KZN88904.1 - 0.21 11.7 0.0 0.37 10.9 0.0 1.3 1 0 0 1 1 1 0 Phage tail tube protein MFS_1 PF07690.16 KZN88905.1 - 1.7e-37 129.2 35.7 1.8e-32 112.6 23.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 KZN88906.1 - 9.7e-06 24.8 0.0 1.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN88906.1 - 1.6e-05 24.9 10.1 3e-05 24.0 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aa_trans PF01490.18 KZN88907.1 - 2.1e-36 125.5 34.5 2.6e-36 125.2 34.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KZN88907.1 - 0.0015 17.6 13.0 0.0015 17.6 13.0 2.3 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family DUF1979 PF09322.10 KZN88907.1 - 0.073 13.0 0.1 1.4 8.9 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1979) DUF2649 PF10854.8 KZN88907.1 - 0.49 10.7 6.4 1.8 9.0 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2649) Glyco_hydro_76 PF03663.14 KZN88908.1 - 5.6e-112 374.9 16.7 6.6e-112 374.7 16.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KZN88908.1 - 0.0046 16.1 0.9 0.0046 16.1 0.9 2.9 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 MFS_1 PF07690.16 KZN88910.1 - 1.3e-40 139.5 54.9 4.2e-40 137.7 52.9 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily S_4TM PF18159.1 KZN88910.1 - 2.1 7.5 6.9 0.26 10.6 1.7 2.1 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain Zn_clus PF00172.18 KZN88911.1 - 0.00062 19.8 8.7 0.0015 18.6 8.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN88911.1 - 0.01 14.9 0.1 0.019 14.0 0.1 1.5 1 1 0 1 1 1 0 Fungal specific transcription factor domain Dickkopf_N PF04706.12 KZN88911.1 - 6.2 7.4 11.5 3.6 8.2 1.3 2.4 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region ketoacyl-synt PF00109.26 KZN88912.1 - 5.7e-74 248.9 0.1 1e-73 248.0 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KZN88912.1 - 2.2e-64 216.7 0.2 1.2e-62 211.0 0.0 3.1 4 0 0 4 4 4 1 KR domain Acyl_transf_1 PF00698.21 KZN88912.1 - 3e-48 165.0 0.2 5.5e-48 164.1 0.2 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KZN88912.1 - 6e-48 163.6 0.0 9.5e-48 162.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KZN88912.1 - 6.4e-37 126.2 0.2 2.5e-36 124.2 0.2 2.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 KZN88912.1 - 1.1e-18 68.6 0.0 4.3e-18 66.6 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 KZN88912.1 - 2.6e-17 63.3 0.0 9.1e-17 61.5 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 KZN88912.1 - 2.4e-16 59.9 0.0 1.2e-15 57.6 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 KZN88912.1 - 3.7e-14 52.7 0.0 1.6e-13 50.6 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Thiolase_N PF00108.23 KZN88912.1 - 6.8e-07 28.9 0.2 1.6e-06 27.7 0.2 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 KZN88912.1 - 1e-06 29.0 0.0 3.1e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ThiF PF00899.21 KZN88912.1 - 0.0075 15.6 0.3 0.019 14.3 0.2 1.7 2 0 0 2 2 2 1 ThiF family ketoacyl-synt PF00109.26 KZN88913.1 - 1.5e-64 218.0 0.0 2.6e-64 217.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KZN88913.1 - 3e-56 190.8 0.4 1.4e-55 188.6 0.0 2.1 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 KZN88913.1 - 5.1e-38 131.4 0.0 7.7e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KZN88913.1 - 7.6e-38 129.2 0.1 3.9e-37 126.9 0.1 2.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 KZN88913.1 - 2.8e-14 53.8 0.0 6.4e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 KZN88913.1 - 1.7e-09 37.9 0.5 5.6e-09 36.2 0.5 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site PS-DH PF14765.6 KZN88913.1 - 2.3e-09 36.9 0.0 8.8e-09 35.0 0.0 1.9 1 1 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KZN88913.1 - 4.5e-06 27.1 0.0 1.5e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KZN88913.1 - 0.065 12.6 0.0 0.4 10.0 0.0 2.2 3 0 0 3 3 3 0 Thiolase, N-terminal domain HET PF06985.11 KZN88914.1 - 4.7e-09 36.7 0.2 8.6e-09 35.9 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RhgB_N PF09284.10 KZN88915.1 - 4.6e-88 295.0 3.4 6.9e-88 294.4 3.4 1.2 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 KZN88915.1 - 1.3e-33 116.2 0.0 3.3e-33 114.9 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KZN88915.1 - 5.3e-16 58.2 1.3 5.3e-16 58.2 1.3 3.2 2 1 0 2 2 2 1 Polysaccharide lyase family 4, domain II CARDB PF07705.11 KZN88915.1 - 0.032 14.5 8.4 0.92 9.8 0.4 3.4 4 0 0 4 4 4 0 CARDB DUF2141 PF09912.9 KZN88915.1 - 0.092 12.7 0.1 3.3 7.7 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2141) DUF2012 PF09430.10 KZN88915.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) DGF-1_4 PF11024.8 KZN88915.1 - 0.82 10.5 7.7 0.3 11.9 2.7 2.6 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 Toxin_37 PF11415.8 KZN88917.1 - 0.42 10.5 7.8 6 6.8 0.0 2.6 2 0 0 2 2 2 0 Antifungal peptide termicin NAPRTase PF04095.16 KZN88918.1 - 7e-53 179.7 0.3 9.3e-52 176.0 0.3 2.0 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KZN88918.1 - 2.5e-33 115.1 0.1 4.4e-33 114.3 0.1 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Pkinase PF00069.25 KZN88919.1 - 8.2e-19 68.0 0.0 1.1e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN88919.1 - 1.1e-17 64.2 0.0 1.5e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KZN88919.1 - 0.0028 17.6 2.5 0.0051 16.8 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KZN88919.1 - 0.0065 15.8 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PIP49_C PF12260.8 KZN88919.1 - 0.095 12.3 0.0 0.27 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 CobT PF06213.12 KZN88919.1 - 3.3 7.0 17.8 4.7 6.5 17.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT GATase PF00117.28 KZN88920.1 - 0.00022 21.1 0.0 0.00026 20.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Multi_ubiq PF14452.6 KZN88920.1 - 0.0062 16.8 0.0 3 8.2 0.0 2.2 2 0 0 2 2 2 2 Multiubiquitin FAD_binding_4 PF01565.23 KZN88921.1 - 1.2e-18 67.1 2.6 2e-18 66.5 2.0 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KZN88921.1 - 6.2e-07 29.4 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.25 KZN88922.1 - 9.3e-18 64.4 0.1 7.5e-12 45.1 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KZN88922.1 - 1.9e-07 30.9 0.0 0.00066 19.3 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KZN88922.1 - 1.9e-05 24.7 0.1 3.1e-05 24.0 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KZN88922.1 - 0.0084 16.0 0.1 0.017 15.1 0.1 1.5 1 0 0 1 1 1 1 KR domain Asn_synthase PF00733.21 KZN88924.1 - 6.9e-68 229.9 0.0 9.2e-68 229.5 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 KZN88924.1 - 5.9e-35 119.9 0.0 1.2e-34 118.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KZN88924.1 - 1.1e-28 100.1 0.0 2.2e-28 99.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KZN88924.1 - 0.00039 20.0 0.0 0.00072 19.1 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein tRNA_Me_trans PF03054.16 KZN88924.1 - 0.075 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase AMP-binding PF00501.28 KZN88925.1 - 6.1e-138 460.0 0.0 1.1e-75 254.8 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KZN88925.1 - 7.3e-81 272.1 0.0 1.2e-40 139.6 0.0 3.6 4 0 0 4 4 4 3 Condensation domain PP-binding PF00550.25 KZN88925.1 - 9.1e-21 74.0 0.1 2.6e-10 40.5 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KZN88925.1 - 4.6e-07 30.7 0.0 0.0045 17.9 0.0 2.9 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 KZN88926.1 - 3.5e-22 78.7 0.6 6.6e-22 77.8 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Swi3 PF07962.12 KZN88926.1 - 0.12 12.3 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Replication Fork Protection Component Swi3 Tom6 PF17112.5 KZN88927.1 - 0.0017 17.8 0.2 0.0023 17.4 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom6, fungal CTNNBL PF08216.11 KZN88928.1 - 2.4e-39 133.7 1.7 5e-39 132.7 0.4 2.3 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Mo25 PF08569.11 KZN88928.1 - 0.0019 17.7 1.6 0.0053 16.2 1.4 1.8 1 1 0 1 1 1 1 Mo25-like Arm PF00514.23 KZN88928.1 - 0.11 12.6 0.0 36 4.6 0.0 3.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF913 PF06025.12 KZN88928.1 - 0.12 11.4 0.4 2.4 7.0 0.0 2.6 2 1 1 3 3 3 0 Domain of Unknown Function (DUF913) DUF5406 PF17400.2 KZN88928.1 - 3.1 8.2 8.9 0.83 10.1 1.6 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5406) RNA_pol_Rpb2_6 PF00562.28 KZN88929.1 - 9.3e-123 410.1 0.0 1.3e-122 409.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KZN88929.1 - 2.1e-60 203.7 0.0 4.1e-60 202.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KZN88929.1 - 1.6e-46 158.3 0.0 2.8e-46 157.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KZN88929.1 - 2.7e-33 114.2 0.0 6e-33 113.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 KZN88929.1 - 2.9e-25 88.2 0.3 7.2e-25 87.0 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 KZN88929.1 - 3.9e-24 84.7 1.0 1.2e-23 83.2 1.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 KZN88929.1 - 1.1e-21 77.2 0.1 3.4e-21 75.6 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 MRNIP PF15749.5 KZN88929.1 - 0.2 12.4 0.0 0.45 11.3 0.0 1.6 1 0 0 1 1 1 0 MRN-interacting protein AMPK1_CBM PF16561.5 KZN88930.1 - 6.8e-05 23.0 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Methyltransf_23 PF13489.6 KZN88931.1 - 9.1e-05 22.4 0.0 0.00013 21.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN88931.1 - 0.012 16.3 0.0 0.024 15.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KZN88931.1 - 0.13 13.0 0.0 0.26 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_S64 PF08192.11 KZN88933.1 - 1.2e-05 24.0 0.0 1.3e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S64 Trypsin_2 PF13365.6 KZN88933.1 - 0.00012 23.0 0.0 0.00016 22.6 0.0 1.1 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KZN88933.1 - 0.046 13.5 0.0 0.059 13.2 0.0 1.1 1 0 0 1 1 1 0 Trypsin ING PF12998.7 KZN88935.1 - 1.6e-23 83.2 3.5 2.6e-23 82.5 3.5 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KZN88935.1 - 3.3e-05 23.7 9.6 5.9e-05 22.9 9.6 1.4 1 0 0 1 1 1 1 PHD-finger Cwf_Cwc_15 PF04889.12 KZN88935.1 - 0.0021 17.8 7.7 0.005 16.6 7.7 1.6 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein zf-HC5HC2H PF13771.6 KZN88935.1 - 0.039 14.2 0.1 0.095 13.0 0.1 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 KZN88935.1 - 0.44 10.2 4.7 0.92 9.1 4.7 1.6 1 0 0 1 1 1 0 PHD-finger RNA_pol_Rpc34 PF05158.12 KZN88936.1 - 1.8e-114 382.6 0.0 2.1e-114 382.4 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_46 PF15977.5 KZN88936.1 - 0.041 13.9 0.1 0.096 12.7 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding MarR PF01047.22 KZN88936.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 MarR family PadR PF03551.14 KZN88936.1 - 0.12 12.4 0.1 0.58 10.2 0.1 2.1 1 1 1 2 2 2 0 Transcriptional regulator PadR-like family TPR_1 PF00515.28 KZN88937.1 - 3.6e-45 150.0 21.5 1.7e-06 27.6 0.1 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 KZN88937.1 - 2.2e-37 126.7 12.9 3.3e-20 71.8 0.2 3.1 3 0 0 3 3 3 2 STI1 domain TPR_2 PF07719.17 KZN88937.1 - 1.2e-35 118.8 20.9 9.4e-05 22.2 0.4 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_11 PF13414.6 KZN88937.1 - 1.7e-19 69.2 20.9 0.00018 21.1 0.1 8.8 5 3 4 9 9 9 5 TPR repeat TPR_12 PF13424.6 KZN88937.1 - 5.1e-18 65.1 18.9 3.2e-07 30.5 0.1 6.5 4 3 2 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 KZN88937.1 - 6.1e-17 60.4 24.8 9e-06 25.5 0.3 8.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 KZN88937.1 - 3.3e-16 59.6 11.8 0.0018 18.9 0.0 6.4 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 KZN88937.1 - 4.4e-14 52.7 15.3 0.035 14.6 0.1 7.5 5 2 2 7 7 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 KZN88937.1 - 3.2e-13 49.3 10.4 0.31 12.0 0.6 9.1 5 3 5 10 10 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 KZN88937.1 - 8e-13 48.3 5.1 0.00097 19.2 0.0 5.3 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KZN88937.1 - 8.3e-11 41.5 5.3 0.065 13.6 0.1 7.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KZN88937.1 - 8.4e-09 34.9 12.0 0.0028 17.6 0.0 7.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 KZN88937.1 - 2.1e-06 27.4 12.6 0.04 13.8 0.1 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KZN88937.1 - 3.2e-06 27.1 2.6 0.099 12.7 0.1 5.4 6 0 0 6 6 6 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 KZN88937.1 - 1e-05 25.8 18.3 0.23 12.2 0.1 8.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_20 PF14561.6 KZN88937.1 - 0.00024 21.3 19.9 0.0017 18.6 0.1 5.5 4 2 1 6 6 6 2 Tetratricopeptide repeat RPN7 PF10602.9 KZN88937.1 - 0.0038 16.9 14.4 0.41 10.3 0.2 5.5 3 3 2 5 5 5 2 26S proteasome subunit RPN7 TPR_3 PF07720.12 KZN88937.1 - 0.015 15.3 12.6 1.5 8.9 0.1 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KZN88937.1 - 0.19 12.1 7.9 1.6 9.2 0.0 3.9 2 2 2 4 4 4 0 Alkyl sulfatase dimerisation MIT PF04212.18 KZN88937.1 - 0.26 11.4 21.9 3.4 7.8 0.1 6.0 6 1 0 6 6 5 0 MIT (microtubule interacting and transport) domain C2 PF00168.30 KZN88938.1 - 4.1e-77 255.1 0.1 2.4e-20 72.8 0.0 5.7 6 0 0 6 6 6 5 C2 domain SMP_LBD PF17047.5 KZN88938.1 - 4.4e-05 23.0 0.0 0.0001 21.9 0.0 1.7 1 1 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain Fungal_trans PF04082.18 KZN88940.1 - 2.9e-11 42.9 0.0 4.8e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN88940.1 - 1.7e-06 28.0 9.7 3.3e-06 27.1 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN88941.1 - 2.7e-21 75.8 2.1 5.3e-21 74.8 2.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN88941.1 - 6.5e-09 35.8 10.8 1.8e-08 34.4 10.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rif1_N PF12231.8 KZN88941.1 - 0.17 10.9 0.0 0.31 10.0 0.0 1.3 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal AP_endonuc_2 PF01261.24 KZN88942.1 - 8e-27 94.0 0.2 7e-26 91.0 0.0 2.0 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel MFS_1 PF07690.16 KZN88943.1 - 6.7e-35 120.6 24.7 8.9e-27 93.9 17.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KZN88943.1 - 0.0014 17.3 14.2 0.0086 14.7 4.5 2.9 3 0 0 3 3 3 2 MFS/sugar transport protein OATP PF03137.20 KZN88943.1 - 0.0062 14.9 7.1 0.23 9.7 1.8 3.0 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Trp_oprn_chp PF09534.10 KZN88943.1 - 0.37 10.6 4.9 1.3 8.7 0.7 2.4 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) AMP-binding PF00501.28 KZN88944.1 - 3.9e-60 203.6 0.0 7.3e-60 202.7 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 KZN88944.1 - 0.0011 19.9 0.0 0.0029 18.5 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AT_hook PF02178.19 KZN88945.1 - 0.00013 21.4 32.9 0.015 15.1 2.9 4.4 4 0 0 4 4 4 3 AT hook motif ABC_membrane PF00664.23 KZN88947.1 - 0.0051 16.5 0.4 0.0057 16.3 0.4 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region FAD_binding_3 PF01494.19 KZN88948.1 - 2.2e-76 257.4 0.0 2.8e-76 257.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KZN88948.1 - 1e-24 87.4 0.0 1.8e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 KZN88948.1 - 1.9e-08 33.9 0.1 0.0018 17.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KZN88948.1 - 1.3e-06 28.3 0.1 0.0016 18.1 0.0 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KZN88948.1 - 5e-05 23.8 0.0 0.0029 18.1 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KZN88948.1 - 0.00041 19.2 0.2 0.00081 18.2 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 KZN88948.1 - 0.00075 19.7 0.0 0.0017 18.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KZN88948.1 - 0.0031 16.9 0.0 0.0054 16.0 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KZN88948.1 - 0.0048 16.0 0.1 0.0076 15.3 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 KZN88948.1 - 0.0058 16.0 0.0 0.58 9.5 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KZN88948.1 - 0.015 14.6 0.0 0.031 13.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KZN88948.1 - 0.018 13.9 0.2 0.18 10.6 0.1 2.0 1 1 1 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 KZN88948.1 - 0.026 13.8 0.1 0.055 12.7 0.1 1.5 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 KZN88948.1 - 0.04 13.3 0.1 0.083 12.2 0.1 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KZN88948.1 - 0.067 12.3 0.1 0.14 11.2 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain PlyB_C PF18684.1 KZN88948.1 - 0.07 12.8 0.0 0.9 9.2 0.0 2.3 2 0 0 2 2 2 0 Pleurotolysin B C-terminal domain 3HCDH_N PF02737.18 KZN88948.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KZN88948.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding XdhC_C PF13478.6 KZN88948.1 - 0.15 12.6 0.0 1.3 9.5 0.0 2.2 2 0 0 2 2 2 0 XdhC Rossmann domain FAD_binding_3 PF01494.19 KZN88949.1 - 1e-10 41.4 0.0 9.8e-10 38.2 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KZN88949.1 - 1.7e-07 31.2 2.8 0.012 15.2 3.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KZN88949.1 - 8.3e-07 28.5 0.7 0.00051 19.4 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KZN88949.1 - 1.8e-06 27.1 1.7 0.0051 15.7 0.1 2.1 1 1 1 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.14 KZN88949.1 - 8.6e-05 21.4 1.6 0.00045 19.1 1.6 1.9 1 1 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KZN88949.1 - 0.0002 20.6 4.8 0.0002 20.6 4.8 1.6 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KZN88949.1 - 0.0012 17.9 2.3 0.0068 15.5 2.3 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein 3HCDH_N PF02737.18 KZN88949.1 - 0.0015 18.4 0.6 0.0027 17.6 0.6 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 KZN88949.1 - 0.0019 18.4 2.6 0.0052 17.0 1.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KZN88949.1 - 0.0025 18.3 0.4 0.081 13.5 0.5 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KZN88949.1 - 0.0092 15.4 2.3 0.017 14.5 2.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KZN88949.1 - 0.013 14.8 0.2 0.029 13.7 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KZN88949.1 - 0.025 13.8 1.0 0.055 12.7 0.6 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KZN88949.1 - 0.03 13.4 3.5 0.048 12.7 3.5 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 KZN88949.1 - 0.044 13.0 0.2 0.075 12.3 0.2 1.3 1 0 0 1 1 1 0 Thi4 family Lactamase_B PF00753.27 KZN88950.1 - 0.0024 17.9 0.0 0.0058 16.7 0.0 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KZN88950.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Chlorosome_CsmC PF11098.8 KZN88951.1 - 0.00048 20.1 3.4 0.00062 19.8 3.4 1.1 1 0 0 1 1 1 1 Chlorosome envelope protein C MFS_1 PF07690.16 KZN88952.1 - 6.7e-26 91.0 48.3 3.8e-24 85.3 29.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN88952.1 - 4.5e-17 62.0 17.5 7.4e-17 61.3 17.3 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1962 PF09227.10 KZN88953.1 - 1.2e-39 134.4 19.0 1.5e-39 134.2 19.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1962) MFS_1 PF07690.16 KZN88954.1 - 1.1e-43 149.5 35.7 1.1e-43 149.5 35.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN88954.1 - 1.2e-11 44.1 7.8 1.2e-11 44.1 7.8 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KZN88954.1 - 6.8e-07 28.1 1.6 6.8e-07 28.1 1.6 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KZN88954.1 - 0.0014 17.1 0.4 0.0014 17.1 0.4 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector DUF5087 PF17006.5 KZN88954.1 - 0.76 9.3 2.4 1.2 8.6 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5087) Zn_clus PF00172.18 KZN88955.1 - 0.011 15.8 10.2 0.02 15.0 10.2 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L7Ae PF01248.26 KZN88956.1 - 4.2e-26 90.5 0.0 5.1e-26 90.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KZN88956.1 - 0.00013 22.1 0.0 0.00013 22.0 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 KZN88956.1 - 0.005 16.7 0.0 0.0076 16.1 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain MFS_1 PF07690.16 KZN88957.1 - 5.1e-30 104.6 28.3 5.1e-30 104.6 28.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NAD_binding_6 PF08030.12 KZN88958.1 - 5.3e-19 68.9 0.0 9.6e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KZN88958.1 - 5e-17 62.2 9.6 1.2e-16 60.9 9.6 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KZN88958.1 - 1.6e-05 24.9 0.1 6.2e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 KZN88958.1 - 0.17 12.5 0.0 5.4 7.7 0.0 2.8 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain PSDC PF12588.8 KZN88959.1 - 4.1e-59 198.6 0.0 5.9e-59 198.0 0.0 1.2 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 KZN88959.1 - 2.5e-38 131.7 0.0 4.8e-38 130.7 0.0 1.4 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.6 KZN88959.1 - 0.013 15.3 0.6 5.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Biotin-lipoyl like COesterase PF00135.28 KZN88960.1 - 8.4e-92 308.7 0.0 1.4e-91 308.0 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KZN88960.1 - 2.4e-09 37.4 0.1 1e-08 35.3 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KZN88960.1 - 2.7e-05 23.8 0.2 4.8e-05 22.9 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Lectin_C PF00059.21 KZN88960.1 - 0.06 14.1 0.2 0.12 13.1 0.2 1.6 1 0 0 1 1 1 0 Lectin C-type domain APH PF01636.23 KZN88962.1 - 5.6e-17 62.5 0.0 3e-16 60.1 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN88962.1 - 1.5e-05 24.7 0.1 3.5e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.22 KZN88962.1 - 0.021 14.4 0.0 0.1 12.2 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 KZN88962.1 - 0.078 12.3 0.0 0.34 10.2 0.0 1.9 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KZN88962.1 - 0.14 11.5 0.0 0.45 9.8 0.0 1.7 2 0 0 2 2 2 0 Protein kinase domain MFS_1 PF07690.16 KZN88963.1 - 7.1e-22 77.8 22.0 7.1e-22 77.8 22.0 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily LAGLIDADG_3 PF14528.6 KZN88964.1 - 0.17 12.2 0.2 0.92 9.9 0.0 2.2 2 0 0 2 2 2 0 LAGLIDADG-like domain Arrestin_N PF00339.29 KZN88965.1 - 7e-05 22.9 0.0 0.00012 22.1 0.0 1.4 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Mid2 PF04478.12 KZN88966.1 - 0.043 13.7 0.0 0.048 13.5 0.0 1.1 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF3040 PF11239.8 KZN88966.1 - 0.07 13.4 0.2 0.13 12.5 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) DUF2207 PF09972.9 KZN88966.1 - 0.093 11.5 0.0 0.093 11.5 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Amidase PF01425.21 KZN88967.1 - 4.6e-89 299.4 0.0 5.8e-89 299.1 0.0 1.1 1 0 0 1 1 1 1 Amidase Fungal_trans_2 PF11951.8 KZN88968.1 - 7.7e-06 25.0 0.5 5.5e-05 22.2 0.1 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KZN88969.1 - 6.9e-06 25.2 27.9 0.00012 21.1 27.9 2.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KZN88970.1 - 3.2e-08 32.8 0.6 5.5e-08 32.0 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN88970.1 - 2.1e-05 24.5 9.4 4e-05 23.7 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.23 KZN88971.1 - 1.7e-09 38.0 0.2 8.5e-09 35.7 0.0 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 KZN88971.1 - 1.8e-07 30.8 0.0 3.6e-07 29.8 0.0 1.4 1 1 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KZN88971.1 - 0.037 13.6 0.0 0.49 9.9 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase FAD_binding_1 PF00667.20 KZN88972.1 - 1.4e-48 165.4 0.0 2e-48 164.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KZN88972.1 - 4e-30 104.9 0.1 9.3e-30 103.7 0.1 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KZN88972.1 - 2.9e-21 76.2 0.0 8.6e-21 74.6 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KZN88972.1 - 0.12 12.5 0.0 1.5 8.9 0.0 2.5 2 0 0 2 2 2 0 Ferric reductase NAD binding domain NmrA PF05368.13 KZN88974.1 - 4.9e-14 52.5 0.1 6.3e-14 52.1 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KZN88974.1 - 7.3e-11 42.3 0.0 1.4e-10 41.4 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding adh_short_C2 PF13561.6 KZN88974.1 - 2.3e-06 27.4 0.1 6.8e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN88974.1 - 1.3e-05 24.7 0.1 0.0001 21.8 0.0 2.3 3 0 0 3 3 3 1 short chain dehydrogenase Epimerase PF01370.21 KZN88974.1 - 1.8e-05 24.3 0.0 9.4e-05 22.0 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KZN88974.1 - 0.0028 17.6 0.1 0.01 15.8 0.0 1.8 2 1 0 3 3 3 1 KR domain ELFV_dehydrog PF00208.21 KZN88974.1 - 0.029 14.1 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase RmlD_sub_bind PF04321.17 KZN88974.1 - 0.073 12.2 0.0 0.12 11.4 0.0 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain TrkA_N PF02254.18 KZN88974.1 - 0.1 12.9 0.0 0.25 11.6 0.0 1.6 1 1 0 1 1 1 0 TrkA-N domain GDP_Man_Dehyd PF16363.5 KZN88974.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 KZN88974.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 KZN88974.1 - 0.12 11.7 0.1 0.21 10.9 0.1 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_hydro_3_C PF01915.22 KZN88975.1 - 3.5e-43 147.9 0.0 8.6e-43 146.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KZN88975.1 - 2.4e-38 132.3 0.0 4.9e-38 131.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KZN88975.1 - 9e-21 73.8 0.1 1.7e-20 72.9 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain FAD_binding_4 PF01565.23 KZN88977.1 - 2.5e-20 72.6 0.1 4.7e-20 71.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FYVE PF01363.21 KZN88978.1 - 5.2e-21 74.6 9.6 2.6e-20 72.3 0.4 3.4 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 KZN88978.1 - 4.1e-08 33.4 26.4 8.5e-08 32.4 6.1 3.5 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.6 KZN88978.1 - 6.9e-05 22.6 6.3 6.9e-05 22.6 6.3 3.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KZN88978.1 - 0.00022 20.9 6.3 0.00022 20.9 6.3 2.7 3 0 0 3 3 3 1 RING-like zinc finger zf-rbx1 PF12678.7 KZN88978.1 - 0.00025 21.3 4.5 0.00025 21.3 4.5 3.4 3 1 0 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KZN88978.1 - 0.021 14.7 6.0 0.021 14.7 6.0 3.6 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KZN88978.1 - 2.6 8.2 11.4 0.18 11.9 1.4 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_clus PF00172.18 KZN88979.1 - 2.2e-05 24.5 12.2 3.7e-05 23.8 12.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN88979.1 - 0.0034 16.4 0.0 0.0062 15.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 KZN88980.1 - 1.2e-56 192.4 0.0 1.7e-56 191.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TRP PF06011.12 KZN88981.1 - 3.9e-40 137.9 22.7 1.1e-32 113.4 19.3 2.1 1 1 1 2 2 2 2 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KZN88981.1 - 8.5e-13 48.9 0.0 1.3e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 ML-like domain YdaS_antitoxin PF15943.5 KZN88982.1 - 0.19 11.6 0.0 3.8 7.4 0.0 2.5 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Cys_Met_Meta_PP PF01053.20 KZN88983.1 - 5.9e-62 209.4 0.0 1.3e-61 208.3 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KZN88983.1 - 0.012 14.6 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Aminotran_1_2 PF00155.21 KZN88983.1 - 0.026 13.7 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II ThiS PF02597.20 KZN88984.1 - 4.7e-11 43.2 0.0 5.2e-11 43.0 0.0 1.0 1 0 0 1 1 1 1 ThiS family NfeD PF01957.18 KZN88984.1 - 0.14 12.6 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding MARVEL PF01284.23 KZN88985.1 - 0.13 12.3 13.8 0.22 11.5 13.8 1.4 1 1 0 1 1 1 0 Membrane-associating domain FAD_binding_4 PF01565.23 KZN88986.1 - 1.1e-21 77.0 1.5 1.8e-21 76.4 1.5 1.3 1 0 0 1 1 1 1 FAD binding domain MFS_1 PF07690.16 KZN88987.1 - 2.1e-38 132.1 50.3 2.1e-38 132.1 50.3 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2987 PF11205.8 KZN88988.1 - 0.01 15.7 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2987) RNB PF00773.19 KZN88989.1 - 2e-51 175.3 0.0 3.4e-39 135.1 0.0 2.2 1 1 1 2 2 2 2 RNB domain HTH_37 PF13744.6 KZN88989.1 - 0.064 13.2 0.3 13 5.9 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain MARVEL PF01284.23 KZN88990.1 - 1.4e-09 38.1 13.5 1.8e-09 37.7 13.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain Frag1 PF10277.9 KZN88991.1 - 6.4e-44 150.1 15.1 7.3e-44 149.9 15.1 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF973 PF06157.11 KZN88991.1 - 0.2 10.7 3.8 0.063 12.3 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF973) Na_Ca_ex PF01699.24 KZN88991.1 - 2.1 8.3 14.2 1.3 9.0 7.2 2.7 1 1 1 2 2 2 0 Sodium/calcium exchanger protein YpzI PF14140.6 KZN88992.1 - 0.37 10.6 18.5 3.6 7.4 0.1 5.3 5 0 0 5 5 5 0 YpzI-like protein AMP-binding PF00501.28 KZN88993.1 - 8e-66 222.4 0.0 1.1e-65 221.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KZN88993.1 - 8.8e-13 49.0 0.1 4e-12 47.0 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain BolA PF01722.18 KZN88994.1 - 9.3e-30 102.7 2.6 1.2e-29 102.4 2.6 1.2 1 0 0 1 1 1 1 BolA-like protein Syntaxin PF00804.25 KZN88995.1 - 5.6e-12 45.8 9.9 9.5e-12 45.0 9.9 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KZN88995.1 - 1.4e-11 44.2 0.1 1.4e-11 44.2 0.1 2.8 3 0 0 3 3 3 1 SNARE domain Phage_prot_Gp6 PF05133.14 KZN88995.1 - 0.0042 16.3 0.9 0.11 11.5 0.0 2.1 1 1 1 2 2 2 1 Phage portal protein, SPP1 Gp6-like Syntaxin_2 PF14523.6 KZN88995.1 - 0.011 16.1 3.9 0.011 16.1 3.9 3.1 2 2 1 3 3 3 0 Syntaxin-like protein T7SS_ESX_EspC PF10824.8 KZN88995.1 - 0.011 16.1 3.0 3.8 8.1 0.3 3.7 2 1 2 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm COG5 PF10392.9 KZN88995.1 - 0.014 15.5 8.8 0.026 14.7 0.7 3.0 3 0 0 3 3 3 0 Golgi transport complex subunit 5 VitD-bind_III PF09164.10 KZN88995.1 - 0.017 15.1 0.1 0.056 13.4 0.1 1.8 1 0 0 1 1 1 0 Vitamin D binding protein, domain III Spore_III_AB PF09548.10 KZN88995.1 - 0.019 15.1 0.5 0.11 12.6 0.1 2.2 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) CD225 PF04505.12 KZN88995.1 - 0.035 14.3 0.5 0.066 13.4 0.5 1.4 1 0 0 1 1 1 0 Interferon-induced transmembrane protein DUF2207 PF09972.9 KZN88995.1 - 0.054 12.3 3.1 0.14 10.9 0.0 2.0 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) IZUMO PF15005.6 KZN88995.1 - 0.23 12.0 3.6 0.73 10.4 0.3 2.1 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated HisKA_3 PF07730.13 KZN88995.1 - 0.26 11.8 4.9 1.3 9.6 0.1 3.4 2 2 2 4 4 4 0 Histidine kinase BshC PF10079.9 KZN88995.1 - 0.29 9.8 8.7 0.031 13.0 2.6 1.9 1 1 1 2 2 2 0 Bacillithiol biosynthesis BshC MCPsignal PF00015.21 KZN88995.1 - 0.37 10.6 6.2 0.29 10.9 2.1 2.5 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Fib_alpha PF08702.10 KZN88995.1 - 1.3 9.2 11.0 2.3 8.4 0.9 2.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.19 KZN88995.1 - 1.5 6.7 6.3 3.3 5.5 5.7 1.8 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF948 PF06103.11 KZN88995.1 - 1.6 9.1 5.1 2.9 8.2 0.3 3.3 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) YscO PF07321.12 KZN88995.1 - 2 8.4 15.4 0.45 10.5 11.0 2.0 2 0 0 2 2 2 0 Type III secretion protein YscO LMBR1 PF04791.16 KZN88995.1 - 2.3 7.0 7.8 4.2 6.1 7.8 1.5 1 1 0 1 1 1 0 LMBR1-like membrane protein NPV_P10 PF05531.12 KZN88995.1 - 3.5 8.2 5.8 2.3 8.8 0.1 3.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 KZN88995.1 - 4.4 7.3 9.5 24 5.0 0.5 3.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.11 KZN88995.1 - 6.5 7.4 10.6 3.7 8.2 0.6 3.3 1 1 2 3 3 3 0 Syntaxin 6, N-terminal PTR2 PF00854.21 KZN88996.1 - 5.5e-91 305.3 10.5 9.2e-91 304.6 10.5 1.3 1 0 0 1 1 1 1 POT family IF4E PF01652.18 KZN88997.1 - 6.4e-53 178.8 0.4 8.1e-53 178.5 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mpv17_PMP22 PF04117.12 KZN88998.1 - 2.3e-22 79.0 2.3 2.3e-22 79.0 2.3 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family Ribosomal_S5 PF00333.20 KZN88999.1 - 2.9e-25 88.0 1.1 8e-25 86.6 0.5 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KZN88999.1 - 3.7e-23 80.8 0.0 6.5e-23 80.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 KZN88999.1 - 0.47 11.0 11.7 1 9.9 11.7 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Glyco_hydro_31 PF01055.26 KZN89000.1 - 5.8e-145 483.8 3.4 8.2e-145 483.3 3.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KZN89000.1 - 6.9e-37 126.2 0.0 1.4e-36 125.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KZN89000.1 - 4.1e-13 49.4 1.1 4.1e-13 49.4 1.1 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like HC2 PF07382.11 KZN89001.1 - 0.29 11.2 10.3 0.76 9.8 4.3 2.1 1 1 1 2 2 2 0 Histone H1-like nucleoprotein HC2 Bac_rhodopsin PF01036.18 KZN89002.1 - 1.8e-31 109.5 12.8 2.3e-31 109.1 12.8 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein UPF0093 PF03653.13 KZN89002.1 - 0.07 13.4 2.6 0.17 12.1 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0093) Anoctamin PF04547.12 KZN89002.1 - 0.43 9.3 3.4 0.19 10.6 0.4 1.6 1 1 1 2 2 2 0 Calcium-activated chloride channel DUF485 PF04341.12 KZN89002.1 - 1.4 8.9 11.4 0.13 12.2 1.3 3.4 2 2 1 3 3 3 0 Protein of unknown function, DUF485 tRNA-synt_1 PF00133.22 KZN89003.1 - 8.4e-159 529.6 0.0 1.1e-158 529.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KZN89003.1 - 4.4e-21 75.1 0.1 6.5e-13 48.2 0.0 3.7 3 1 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KZN89003.1 - 1.4e-19 70.6 0.4 2.3e-19 69.8 0.4 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.14 KZN89003.1 - 0.00066 19.5 3.4 0.0013 18.6 3.4 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.6 KZN89003.1 - 0.0028 17.2 0.0 0.0054 16.3 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KZN89003.1 - 0.092 12.1 0.0 5.5 6.2 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain ABC_membrane PF00664.23 KZN89004.1 - 1.8e-79 267.3 35.5 1.7e-43 149.3 12.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KZN89004.1 - 2.7e-66 222.3 0.0 3.7e-33 114.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KZN89004.1 - 3.6e-12 46.2 3.1 0.0011 18.4 0.0 4.1 2 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KZN89004.1 - 1.1e-07 31.5 0.7 0.004 16.9 0.3 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KZN89004.1 - 4.4e-07 30.2 0.6 0.016 15.5 0.0 3.8 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KZN89004.1 - 9.8e-07 28.8 0.0 0.026 14.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 KZN89004.1 - 3.8e-06 26.0 2.3 0.058 12.2 0.0 3.1 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_25 PF13481.6 KZN89004.1 - 3.9e-06 26.6 0.2 0.092 12.3 0.1 3.3 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 KZN89004.1 - 4.4e-06 26.6 0.0 0.046 13.4 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_7 PF12775.7 KZN89004.1 - 7.5e-05 22.3 0.0 0.15 11.5 0.0 2.9 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_16 PF13191.6 KZN89004.1 - 8.6e-05 23.0 3.9 0.25 11.7 0.3 3.6 2 2 1 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 KZN89004.1 - 0.00014 21.8 0.2 4.4 7.0 0.1 4.3 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KZN89004.1 - 0.00017 21.7 1.2 1.3 9.3 0.1 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 KZN89004.1 - 0.00079 19.2 1.5 1.3 8.7 0.0 3.4 2 2 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KZN89004.1 - 0.0039 17.7 0.0 2.7 8.4 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KZN89004.1 - 0.0041 17.3 0.0 3.6 7.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KZN89004.1 - 0.0055 16.0 0.0 4.2 6.6 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_28 PF13521.6 KZN89004.1 - 0.0057 16.9 0.3 0.75 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 KZN89004.1 - 0.0071 15.5 0.0 3 6.9 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA PF00004.29 KZN89004.1 - 0.015 15.7 0.5 46 4.4 0.0 4.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KZN89004.1 - 0.017 15.2 0.0 3.3 7.8 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase DEAD PF00270.29 KZN89004.1 - 0.023 14.5 0.1 1.7 8.4 0.0 3.1 4 0 0 4 4 3 0 DEAD/DEAH box helicase AAA_5 PF07728.14 KZN89004.1 - 0.03 14.3 0.2 13 5.8 0.0 3.4 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KZN89004.1 - 0.045 14.3 0.0 16 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KZN89004.1 - 0.063 12.5 0.3 2.6 7.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain APS_kinase PF01583.20 KZN89004.1 - 0.07 13.0 0.1 2.7 7.9 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.22 KZN89004.1 - 0.085 13.2 0.0 5.3 7.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.17 KZN89004.1 - 0.1 12.7 0.2 2.7 8.0 0.1 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain UPF0183 PF03676.14 KZN89005.1 - 1.5e-52 179.3 0.0 1.1e-34 120.4 0.0 2.9 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0183) Kinesin PF00225.23 KZN89006.1 - 2e-110 368.9 0.5 2e-110 368.9 0.5 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KZN89006.1 - 3.5e-24 85.4 0.0 1.6e-23 83.3 0.0 2.2 1 0 0 1 1 1 1 Microtubule binding Microtub_bind PF13931.6 KZN89006.1 - 2e-08 34.7 2.2 2e-08 34.7 2.2 4.4 4 1 1 5 5 5 1 Kinesin-associated microtubule-binding Baculo_PEP_C PF04513.12 KZN89006.1 - 0.00017 21.6 15.0 0.035 14.2 0.0 5.2 2 1 3 7 7 7 2 Baculovirus polyhedron envelope protein, PEP, C terminus RNase_H2-Ydr279 PF09468.10 KZN89006.1 - 0.064 13.4 2.7 0.2 11.8 1.7 2.4 1 1 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain PTPlike_phytase PF14566.6 KZN89006.1 - 0.57 10.3 8.0 0.55 10.3 4.6 2.9 2 0 0 2 2 2 0 Inositol hexakisphosphate DAP_B PF07930.12 KZN89006.1 - 1 9.3 4.7 16 5.4 0.7 2.7 2 0 0 2 2 2 0 D-aminopeptidase, domain B DUF4854 PF16146.5 KZN89006.1 - 1.1 9.6 6.4 2.2 8.7 0.3 3.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4854) TBCA PF02970.16 KZN89006.1 - 2 8.8 25.0 0.043 14.1 4.5 4.6 4 1 1 5 5 5 0 Tubulin binding cofactor A TMPIT PF07851.13 KZN89006.1 - 2 7.6 25.5 4.2 6.5 0.2 4.5 4 0 0 4 4 4 0 TMPIT-like protein BLOC1_2 PF10046.9 KZN89006.1 - 2.3 8.5 18.6 1.6 9.0 1.4 5.3 3 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Gp-FAR-1 PF05823.12 KZN89006.1 - 8.9 6.7 9.8 1.4 9.3 2.2 3.4 3 0 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) zf-ANAPC11 PF12861.7 KZN89008.1 - 1.1e-46 156.8 10.1 1.2e-46 156.6 10.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KZN89008.1 - 1e-20 73.8 10.6 1.3e-20 73.4 10.6 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KZN89008.1 - 2.7e-07 30.8 15.6 7.6e-06 26.2 15.6 2.5 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KZN89008.1 - 0.00029 20.6 4.4 0.00029 20.6 4.4 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KZN89008.1 - 0.0072 16.5 14.6 0.12 12.5 14.6 2.9 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 KZN89008.1 - 0.01 15.6 12.2 0.37 10.7 12.3 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KZN89008.1 - 0.011 15.5 11.6 0.62 9.9 8.5 2.7 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 KZN89008.1 - 0.028 14.4 4.3 0.028 14.4 4.3 2.4 2 1 0 2 2 2 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KZN89008.1 - 0.077 12.6 12.5 0.32 10.7 11.7 2.1 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 KZN89008.1 - 0.097 12.6 15.0 0.71 9.8 15.0 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 KZN89008.1 - 0.17 11.8 0.4 4.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_5 PF14634.6 KZN89008.1 - 0.2 11.6 15.6 1.8 8.6 15.8 2.5 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_11 PF17123.5 KZN89008.1 - 0.36 10.6 10.4 3.6 7.4 10.4 2.5 1 1 0 1 1 1 0 RING-like zinc finger PHD PF00628.29 KZN89008.1 - 0.65 9.9 12.8 2.8 7.9 12.8 2.0 1 1 0 1 1 1 0 PHD-finger zf-HIT PF04438.16 KZN89008.1 - 2.7 8.0 7.6 0.31 11.0 1.2 2.3 3 0 0 3 3 2 0 HIT zinc finger Opy2 PF09463.10 KZN89008.1 - 3.3 8.1 10.8 1.9 8.8 6.0 2.5 2 1 1 3 3 3 0 Opy2 protein RINGv PF12906.7 KZN89008.1 - 3.8 7.7 13.9 3.4 7.9 11.4 2.2 1 1 1 2 2 2 0 RING-variant domain zf-RING-like PF08746.11 KZN89008.1 - 5.5 7.4 12.0 38 4.7 12.0 2.3 1 1 0 1 1 1 0 RING-like domain zf-HC5HC2H PF13771.6 KZN89008.1 - 8.3 6.7 12.2 43 4.4 12.1 2.2 1 1 1 2 2 2 0 PHD-like zinc-binding domain Rhodanese PF00581.20 KZN89009.1 - 3.8e-16 59.5 0.0 1.7e-09 38.2 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain PIN_4 PF13638.6 KZN89010.1 - 2.1e-05 24.8 0.1 0.0029 17.9 0.1 2.4 2 0 0 2 2 2 2 PIN domain RPEL PF02755.15 KZN89011.1 - 1.6e-26 91.1 16.6 6.4e-09 35.2 0.9 3.7 4 0 0 4 4 4 3 RPEL repeat Rotamase_3 PF13616.6 KZN89011.1 - 0.0058 17.2 0.5 0.11 13.1 0.1 2.0 1 1 1 2 2 2 2 PPIC-type PPIASE domain Hanta_nucleocap PF00846.18 KZN89011.1 - 0.11 10.9 0.7 0.17 10.3 0.3 1.4 1 1 1 2 2 2 0 Hantavirus nucleocapsid protein Translin PF01997.16 KZN89012.1 - 1.4e-70 237.4 0.0 1.7e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 Translin family REV PF00424.18 KZN89012.1 - 0.17 11.9 0.7 0.47 10.5 0.8 1.7 1 1 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Mannosidase_ig PF17786.1 KZN89013.1 - 4e-19 69.0 0.3 2.9e-18 66.3 0.0 2.3 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KZN89013.1 - 4.2e-16 59.6 0.1 1.1e-15 58.2 0.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 KZN89013.1 - 0.00018 21.5 0.0 0.00054 19.9 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Ig_mannosidase PF17753.1 KZN89013.1 - 0.023 14.4 0.0 0.12 12.2 0.0 2.3 2 0 0 2 2 2 0 Ig-fold domain Fungal_trans PF04082.18 KZN89014.1 - 3.2e-17 62.4 0.1 6.9e-17 61.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN89014.1 - 3.4e-06 27.1 14.6 6.4e-06 26.2 14.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3712 PF12505.8 KZN89015.1 - 2.1e-24 86.2 0.9 2.9e-24 85.7 0.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Calycin_like PF13944.6 KZN89015.1 - 0.06 13.7 0.3 0.11 12.8 0.3 1.5 1 0 0 1 1 1 0 Calycin-like beta-barrel domain Mannosyl_trans PF05007.13 KZN89017.1 - 4.3e-76 256.2 14.1 5.6e-76 255.8 14.1 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KZN89017.1 - 2.1e-09 36.9 19.3 2.1e-08 33.7 19.3 2.0 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 KZN89017.1 - 2.3e-06 27.5 30.0 2.3e-06 27.5 30.0 2.5 1 1 0 1 1 1 1 Glycosyltransferase family 87 NIBRIN_BRCT_II PF16508.5 KZN89018.1 - 1.3e-37 128.8 0.0 3.5e-37 127.3 0.0 1.8 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 KZN89018.1 - 1.4e-09 38.2 0.1 3e-09 37.1 0.1 1.5 1 0 0 1 1 1 1 FHA domain RTT107_BRCT_5 PF16770.5 KZN89018.1 - 0.014 15.2 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain DUF4138 PF13595.6 KZN89018.1 - 0.08 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4138) Yop-YscD_cpl PF16697.5 KZN89018.1 - 0.08 13.3 0.1 0.28 11.5 0.1 2.0 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain IMS PF00817.20 KZN89019.1 - 6.7e-44 149.5 0.5 1.4e-43 148.4 0.5 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KZN89019.1 - 5.3e-17 62.6 0.3 8.9e-16 58.7 0.2 2.5 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KZN89019.1 - 3.3e-06 27.1 0.0 1e-05 25.6 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif BAF PF02961.14 KZN89019.1 - 0.0087 16.5 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 Barrier to autointegration factor DUF2236 PF09995.9 KZN89021.1 - 6.7e-08 33.0 0.1 9.4e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) MARVEL PF01284.23 KZN89022.1 - 8.6e-08 32.3 22.5 1.4e-07 31.7 22.5 1.3 1 0 0 1 1 1 1 Membrane-associating domain DnaJ-X PF14308.6 KZN89023.1 - 8.4e-72 241.0 5.4 8.4e-72 241.0 5.4 2.8 3 1 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.31 KZN89023.1 - 2.6e-25 88.3 0.2 8.1e-25 86.7 0.2 1.9 1 0 0 1 1 1 1 DnaJ domain OrfB_IS605 PF01385.19 KZN89023.1 - 0.11 12.8 1.8 0.34 11.1 1.8 1.8 1 0 0 1 1 1 0 Probable transposase SQS_PSY PF00494.19 KZN89024.1 - 6.8e-36 124.1 0.0 9.5e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Synaptobrevin PF00957.21 KZN89024.1 - 0.043 13.6 0.1 6.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Synaptobrevin DUF5383 PF17355.2 KZN89024.1 - 0.063 13.7 1.4 0.18 12.2 0.1 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5383) Peroxin-22 PF12827.7 KZN89024.1 - 0.069 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family MSP1a PF11670.8 KZN89024.1 - 0.088 12.1 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) Hemerythrin PF01814.23 KZN89025.1 - 2.6e-12 47.5 3.3 3.4e-12 47.1 3.3 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain TPR_9 PF13371.6 KZN89025.1 - 0.071 13.3 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Acetyltransf_7 PF13508.7 KZN89026.1 - 1.9e-09 37.8 0.0 2.4e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KZN89026.1 - 4.5e-09 36.6 0.0 5e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KZN89026.1 - 1.8e-08 34.4 0.0 2.6e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KZN89026.1 - 4.9e-05 23.2 0.0 0.00022 21.1 0.1 1.9 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.7 KZN89026.1 - 0.0056 17.4 0.0 0.0072 17.0 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KZN89026.1 - 0.0094 16.1 0.0 0.017 15.3 0.0 1.5 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Glyco_hydro_114 PF03537.13 KZN89026.1 - 0.17 11.2 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 FAD_binding_3 PF01494.19 KZN89027.1 - 2.1e-13 50.2 0.0 1.3e-12 47.7 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KZN89027.1 - 0.016 14.3 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein TauD PF02668.16 KZN89028.1 - 3.3e-52 177.9 0.5 3.9e-52 177.7 0.5 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AA_permease PF00324.21 KZN89029.1 - 2.3e-111 372.8 41.2 2.8e-111 372.5 41.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KZN89029.1 - 3.6e-27 95.3 43.6 4.4e-27 95.0 43.6 1.0 1 0 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.24 KZN89030.1 - 6.9e-144 480.1 28.2 7.9e-144 479.9 28.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN89030.1 - 3e-21 75.7 37.7 7.3e-15 54.7 13.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cellulase PF00150.18 KZN89031.1 - 4.7e-17 62.3 0.8 6.6e-17 61.8 0.8 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KZN89031.1 - 4.4e-10 39.3 15.8 1.5e-09 37.7 15.8 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.17 KZN89031.1 - 0.00058 19.1 0.0 0.0011 18.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4038 PF13204.6 KZN89031.1 - 0.0014 18.3 0.2 0.0026 17.5 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Glyco_hydro_42 PF02449.15 KZN89031.1 - 0.0073 15.7 0.1 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 Beta-galactosidase DUF2255 PF10012.9 KZN89031.1 - 0.27 11.4 1.7 0.36 11.0 0.7 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2255) Transp_inhibit PF18791.1 KZN89031.1 - 2.6 7.6 3.8 1.4 8.5 0.7 2.2 3 0 0 3 3 3 0 Transport inhibitor response 1 protein domain AA_permease_2 PF13520.6 KZN89032.1 - 1e-48 166.3 55.7 1.3e-48 165.9 55.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN89032.1 - 5.7e-25 87.9 46.9 7.7e-25 87.4 46.9 1.0 1 0 0 1 1 1 1 Amino acid permease GAPT PF11770.8 KZN89032.1 - 0.054 13.4 0.7 0.13 12.2 0.7 1.6 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Acetyltransf_10 PF13673.7 KZN89034.1 - 1.6e-08 34.6 0.0 2.4e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KZN89034.1 - 1.9e-07 31.3 0.0 3.3e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KZN89034.1 - 5e-06 26.9 0.0 8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KZN89034.1 - 0.00054 20.0 0.0 0.0091 16.1 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KZN89034.1 - 0.0011 19.0 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KZN89034.1 - 0.0052 16.7 0.0 0.009 16.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein MFS_1 PF07690.16 KZN89035.1 - 5.1e-22 78.3 49.7 1.8e-21 76.5 49.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KZN89035.1 - 0.00031 19.2 1.8 0.00031 19.2 1.8 2.1 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family UNC-93 PF05978.16 KZN89035.1 - 0.043 13.5 5.9 0.032 13.9 3.4 2.0 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 PSI_PSAK PF01241.18 KZN89035.1 - 0.18 11.8 4.0 0.22 11.6 0.1 3.2 3 0 0 3 3 3 0 Photosystem I psaG / psaK p450 PF00067.22 KZN89036.1 - 5.2e-58 196.9 0.0 6.9e-58 196.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 His_Phos_2 PF00328.22 KZN89037.1 - 9e-19 68.1 0.0 1.3e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Peptidase_S8 PF00082.22 KZN89038.1 - 2e-30 106.1 20.5 3.4e-30 105.3 20.5 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KZN89038.1 - 1.3e-14 54.7 0.0 2.1e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF2252 PF10009.9 KZN89039.1 - 9.1e-116 387.1 1.9 1.1e-115 386.9 1.9 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2252) APH PF01636.23 KZN89039.1 - 0.011 15.6 0.4 0.044 13.7 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf_Hakai PF18408.1 KZN89039.1 - 0.047 13.4 0.8 0.093 12.5 0.8 1.4 1 0 0 1 1 1 0 C2H2 Hakai zinc finger domain Reprolysin_4 PF13583.6 KZN89040.1 - 1.7e-30 106.2 4.4 2.9e-30 105.4 4.4 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KZN89040.1 - 6e-29 101.6 6.2 9.6e-29 100.9 6.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KZN89040.1 - 2.7e-16 60.1 0.8 4.7e-16 59.2 0.8 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 KZN89040.1 - 0.002 18.1 0.2 0.007 16.3 0.2 1.8 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.6 KZN89040.1 - 0.0033 17.9 0.1 0.0074 16.8 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like MFS_1 PF07690.16 KZN89041.1 - 1.4e-27 96.6 27.0 1.4e-27 96.6 27.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily BT1 PF03092.16 KZN89041.1 - 2.4 6.3 8.2 28 2.8 6.0 2.6 2 1 0 2 2 2 0 BT1 family DUF1524 PF07510.11 KZN89042.1 - 1e-09 38.4 0.0 1.2e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.6 KZN89042.1 - 0.25 11.3 0.5 0.78 9.7 0.5 1.8 1 1 0 1 1 1 0 HNH endonuclease Oxidored_FMN PF00724.20 KZN89043.1 - 5.8e-60 203.4 0.0 2.2e-59 201.4 0.0 1.7 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 KZN89043.1 - 0.084 12.3 0.0 0.74 9.2 0.0 2.3 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel Amidohydro_3 PF07969.11 KZN89044.1 - 6.9e-72 243.4 0.2 7.8e-72 243.2 0.2 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KZN89044.1 - 4.2e-12 46.1 0.1 5.6e-07 29.2 0.0 3.1 2 1 0 2 2 2 2 Amidohydrolase family DUF1445 PF07286.12 KZN89045.1 - 4.4e-61 205.0 0.0 5.7e-61 204.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) MFS_1 PF07690.16 KZN89046.1 - 2e-40 138.8 23.4 2.6e-40 138.5 23.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1449 PF07290.11 KZN89046.1 - 2.6 7.6 5.6 0.49 10.0 0.9 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1449) Fungal_trans PF04082.18 KZN89047.1 - 3.8e-09 36.0 0.0 9.3e-09 34.7 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN89047.1 - 3.6e-07 30.2 12.4 6.7e-07 29.3 12.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KZN89048.1 - 1.1e-64 218.9 0.0 1.3e-64 218.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Myb_DNA-binding PF00249.31 KZN89049.1 - 2.3e-09 37.3 0.0 1.6e-06 28.2 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KZN89049.1 - 0.022 14.7 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 Myb DNA-binding like DS PF01916.17 KZN89050.1 - 5e-127 423.1 0.0 5.7e-127 422.9 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Carbam_trans_N PF02543.15 KZN89050.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus MORN PF02493.20 KZN89051.1 - 4.4e-14 51.4 24.1 3.6e-05 23.4 0.7 4.6 4 0 0 4 4 4 4 MORN repeat zf-C3HC4_3 PF13920.6 KZN89051.1 - 2.5e-10 40.1 11.1 3.8e-10 39.5 11.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UCH PF00443.29 KZN89051.1 - 5.6e-09 35.9 0.0 1.2e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Prok-RING_4 PF14447.6 KZN89051.1 - 0.00095 19.0 10.7 0.0018 18.1 10.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 TSKS PF15358.6 KZN89051.1 - 0.66 8.3 2.2 0.88 7.9 1.0 1.7 2 0 0 2 2 2 0 Testis-specific serine kinase substrate zf-RING_5 PF14634.6 KZN89051.1 - 3.7 7.6 11.5 6.7 6.8 11.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Methyltr_RsmB-F PF01189.17 KZN89052.1 - 9.1e-72 240.9 0.0 1.5e-71 240.2 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KZN89052.1 - 7.7e-08 32.7 0.0 2.9e-07 30.9 0.0 2.0 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 KZN89052.1 - 0.016 15.3 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 KZN89052.1 - 0.035 13.8 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Blt1 PF12754.7 KZN89053.1 - 4.8e-70 234.7 0.2 6.1e-70 234.4 0.2 1.1 1 0 0 1 1 1 1 Blt1 N-terminal domain Blt1_C PF17183.4 KZN89053.1 - 6e-27 93.0 0.2 1.2e-26 92.1 0.2 1.5 1 0 0 1 1 1 1 Get5 carboxyl domain Striatin PF08232.12 KZN89054.1 - 1.4e-42 145.9 7.8 1.4e-42 145.9 7.8 2.1 2 0 0 2 2 2 1 Striatin family WD40 PF00400.32 KZN89054.1 - 3.4e-25 87.8 17.2 0.00016 22.4 0.3 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN89054.1 - 0.0011 19.2 0.4 7.6 6.9 0.0 4.4 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KZN89054.1 - 0.054 13.4 0.0 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A ADH_N_2 PF16884.5 KZN89054.1 - 0.12 12.3 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Ge1_WD40 PF16529.5 KZN89054.1 - 0.24 10.3 0.0 0.64 8.9 0.0 1.7 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CENP-Q PF13094.6 KZN89054.1 - 6.2 7.0 14.8 0.24 11.6 8.2 1.9 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit XPA_C PF05181.12 KZN89055.1 - 8.6e-26 89.7 2.2 1.7e-25 88.7 2.2 1.5 1 0 0 1 1 1 1 XPA protein C-terminus YhfH PF14149.6 KZN89055.1 - 0.031 14.3 5.8 0.38 10.8 0.5 2.6 2 0 0 2 2 2 0 YhfH-like protein XPA_N PF01286.18 KZN89055.1 - 1.3 9.1 13.9 0.38 10.8 8.1 2.3 2 0 0 2 2 2 0 XPA protein N-terminal ArfGap PF01412.18 KZN89055.1 - 8.1 6.6 11.4 0.15 12.2 2.7 2.5 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf PIG-P PF08510.12 KZN89056.1 - 1.9e-53 179.5 2.2 3.2e-53 178.8 2.2 1.4 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 KZN89056.1 - 0.17 12.2 9.1 0.29 11.5 9.1 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) 4HBT PF03061.22 KZN89057.1 - 9.4e-13 48.3 0.6 1.6e-12 47.6 0.6 1.3 1 0 0 1 1 1 1 Thioesterase superfamily BATS PF06968.13 KZN89057.1 - 0.01 16.0 0.0 0.022 14.9 0.0 1.4 1 1 0 1 1 1 0 Biotin and Thiamin Synthesis associated domain YdjM PF04307.14 KZN89057.1 - 0.012 14.9 0.3 0.017 14.4 0.3 1.2 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase DUF4442 PF14539.6 KZN89057.1 - 0.023 14.8 0.0 0.028 14.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) adh_short PF00106.25 KZN89058.1 - 1.9e-23 82.9 0.1 2.1e-23 82.8 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN89058.1 - 9.6e-23 81.0 0.1 1.1e-22 80.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RSN1_7TM PF02714.15 KZN89059.1 - 1e-84 284.1 20.5 1e-84 284.1 20.5 2.7 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KZN89059.1 - 1e-42 145.6 1.2 1e-42 145.6 1.2 2.6 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KZN89059.1 - 2.3e-34 119.2 1.3 4.2e-34 118.3 1.3 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KZN89059.1 - 5.1e-29 100.3 0.9 1.4e-28 98.9 0.9 1.7 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter kleA_kleC PF17383.2 KZN89059.1 - 0.016 15.6 2.1 0.021 15.1 0.1 2.2 3 0 0 3 3 3 0 Uncharacterized KorC regulated protein A RRM_1 PF00076.22 KZN89059.1 - 0.049 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4164 PF13747.6 KZN89059.1 - 1.3 9.3 4.9 15 6.0 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Cellulase PF00150.18 KZN89060.1 - 1.4e-40 139.5 1.2 5e-40 137.7 0.5 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.14 KZN89060.1 - 2.3e-24 85.3 4.4 7.2e-21 74.1 1.4 3.6 2 1 0 2 2 2 2 Carbohydrate binding domain X2 MINDY_DUB PF04424.13 KZN89061.1 - 5.6e-20 71.5 0.0 9.9e-20 70.7 0.0 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase Gcd10p PF04189.13 KZN89062.1 - 3.6e-118 394.1 0.0 4.4e-118 393.8 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family Shugoshin_N PF07558.11 KZN89062.1 - 0.025 14.4 0.3 0.062 13.2 0.3 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region AnmK PF03702.14 KZN89062.1 - 0.061 12.4 0.0 7.1 5.6 0.0 2.1 1 1 1 2 2 2 0 Anhydro-N-acetylmuramic acid kinase P21-Arc PF04062.14 KZN89063.1 - 4.2e-70 235.3 0.0 4e-69 232.1 0.0 1.9 1 1 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Rep_fac_C PF08542.11 KZN89064.1 - 2.3e-17 63.1 0.0 9.4e-17 61.2 0.0 2.0 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 KZN89064.1 - 2e-16 60.6 0.0 4.2e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KZN89064.1 - 2.7e-12 46.8 0.2 9.2e-12 45.0 0.0 2.0 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KZN89064.1 - 2.2e-08 34.2 0.0 4.5e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 KZN89064.1 - 6e-07 29.7 0.0 2.3e-06 27.8 0.0 2.1 2 1 0 2 2 1 1 AAA C-terminal domain AAA_16 PF13191.6 KZN89064.1 - 2.3e-06 28.1 0.0 5.5e-05 23.6 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 KZN89064.1 - 3.7e-06 26.8 0.1 8.6e-06 25.6 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 KZN89064.1 - 4.1e-06 27.1 0.1 7.2e-05 23.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KZN89064.1 - 4.6e-06 26.6 0.1 6.5e-05 22.8 0.0 2.2 1 1 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.13 KZN89064.1 - 2.2e-05 24.3 0.0 3.8e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_5 PF07728.14 KZN89064.1 - 2.6e-05 24.2 0.4 0.00011 22.2 0.1 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KZN89064.1 - 6.7e-05 22.2 0.0 0.00012 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 KZN89064.1 - 8.8e-05 22.3 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KZN89064.1 - 0.00013 21.7 0.0 0.00032 20.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 KZN89064.1 - 0.0002 21.7 0.1 0.00074 19.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KZN89064.1 - 0.00022 21.1 0.1 0.0019 18.0 0.1 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KZN89064.1 - 0.00058 19.9 0.0 0.0015 18.6 0.0 1.6 1 1 1 2 2 2 1 AAA domain PhoH PF02562.16 KZN89064.1 - 0.0006 19.3 0.4 0.72 9.3 0.0 2.5 1 1 1 2 2 2 2 PhoH-like protein DEAD PF00270.29 KZN89064.1 - 0.0069 16.2 0.0 0.087 12.6 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase TniB PF05621.11 KZN89064.1 - 0.01 15.3 0.1 0.075 12.4 0.1 2.2 1 1 0 1 1 1 0 Bacterial TniB protein AAA_28 PF13521.6 KZN89064.1 - 0.013 15.8 0.1 0.028 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KZN89064.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 KZN89064.1 - 0.014 15.4 0.0 0.18 11.8 0.0 2.1 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 KZN89064.1 - 0.018 15.6 0.0 0.03 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KZN89064.1 - 0.022 14.3 0.0 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 KZN89064.1 - 0.031 13.5 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 KZN89064.1 - 0.045 13.1 0.2 0.25 10.7 0.1 2.3 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KZN89064.1 - 0.046 13.3 0.0 0.12 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KZN89064.1 - 0.053 13.9 0.0 0.14 12.6 0.0 1.8 1 1 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 KZN89064.1 - 0.076 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 KZN89064.1 - 0.097 13.2 0.0 0.19 12.2 0.0 1.6 1 1 0 1 1 1 0 ABC transporter TIP49 PF06068.13 KZN89064.1 - 0.16 11.1 0.0 0.45 9.7 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain His_Phos_2 PF00328.22 KZN89065.1 - 1.1e-10 41.5 0.0 9.8e-10 38.3 0.0 1.9 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 2) Clr5 PF14420.6 KZN89066.1 - 3.2e-09 36.9 0.4 2.3e-08 34.1 0.0 2.1 2 0 0 2 2 2 1 Clr5 domain HTH_Tnp_Tc3_2 PF01498.18 KZN89066.1 - 9e-06 25.9 2.0 0.0025 18.0 0.4 2.2 2 0 0 2 2 2 2 Transposase HTH_12 PF08461.10 KZN89066.1 - 0.0011 18.9 2.3 0.32 11.0 0.2 2.4 1 1 2 3 3 3 2 Ribonuclease R winged-helix domain HTH_32 PF13565.6 KZN89066.1 - 0.0021 18.6 0.8 0.38 11.4 0.1 2.2 1 1 1 2 2 2 2 Homeodomain-like domain Terminase_5 PF06056.12 KZN89066.1 - 0.025 14.5 0.2 0.074 13.0 0.2 1.8 1 1 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) SPK PF04435.18 KZN89066.1 - 0.03 14.7 0.1 0.04 14.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF545) DUF4498 PF14926.6 KZN89066.1 - 0.037 13.3 0.0 0.078 12.3 0.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4498) Sigma54_DBD PF04552.13 KZN89066.1 - 0.04 13.6 0.2 0.14 11.8 0.2 1.7 1 1 0 1 1 1 0 Sigma-54, DNA binding domain DDE_Tnp_ISAZ013 PF07592.11 KZN89066.1 - 0.1 11.5 2.0 2.1 7.2 0.2 2.0 1 1 1 2 2 2 0 Rhodopirellula transposase DDE domain Pro_isomerase PF00160.21 KZN89067.1 - 1.9e-38 132.2 0.0 3.7e-38 131.3 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.6 KZN89067.1 - 0.019 15.4 0.1 0.019 15.4 0.1 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4604) HSF_DNA-bind PF00447.17 KZN89068.1 - 1.3e-28 99.4 0.2 2.8e-28 98.4 0.2 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding TMF_DNA_bd PF12329.8 KZN89068.1 - 0.064 13.3 1.5 0.69 9.9 0.2 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Ets PF00178.22 KZN89068.1 - 0.065 13.7 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Ets-domain Aldo_ket_red PF00248.21 KZN89069.1 - 1.1e-15 57.6 0.0 1.1e-14 54.4 0.0 2.0 1 1 0 2 2 2 1 Aldo/keto reductase family SDA1 PF05285.12 KZN89070.1 - 0.09 12.2 7.4 0.1 12.0 7.4 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KZN89070.1 - 0.19 9.9 8.6 0.21 9.8 8.6 1.0 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 KZN89070.1 - 0.21 11.3 16.3 0.33 10.6 16.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 KZN89070.1 - 0.32 10.3 8.6 0.38 10.0 8.6 1.1 1 0 0 1 1 1 0 BUD22 GCIP PF13324.6 KZN89070.1 - 0.39 10.3 3.8 0.49 10.0 3.8 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DNA_pol_phi PF04931.13 KZN89070.1 - 0.46 8.5 13.2 0.55 8.3 13.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 KZN89070.1 - 0.51 8.6 7.2 0.58 8.4 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.9 KZN89070.1 - 1.1 7.7 2.9 1.3 7.5 2.9 1.0 1 0 0 1 1 1 0 Macoilin family RXT2_N PF08595.11 KZN89070.1 - 1.4 8.9 9.1 2.8 8.0 9.1 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal RRN3 PF05327.11 KZN89070.1 - 1.5 7.2 7.0 1.7 7.1 7.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FAM176 PF14851.6 KZN89070.1 - 3.3 7.4 10.2 5.3 6.7 9.8 1.6 1 1 0 1 1 1 0 FAM176 family DUF3431 PF11913.8 KZN89071.1 - 1.6e-85 286.3 2.4 2.2e-85 285.8 2.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) R3H PF01424.22 KZN89072.1 - 9.6e-11 41.5 0.1 1.7e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 KZN89072.1 - 5.1e-06 26.2 0.1 9.7e-06 25.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUZ-C PF12901.7 KZN89072.1 - 0.01 15.8 5.5 0.039 14.0 5.5 2.1 1 0 0 1 1 1 0 SUZ-C motif Histone PF00125.24 KZN89073.1 - 1.1e-16 61.4 0.0 1.4e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KZN89073.1 - 1e-11 44.3 0.0 2e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KZN89073.1 - 3.5e-05 24.0 0.0 4.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pho88 PF10032.9 KZN89074.1 - 5.3e-81 270.2 0.2 6.1e-81 270.0 0.2 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Gp_dh_C PF02800.20 KZN89075.1 - 4.9e-71 237.4 0.1 6.7e-71 237.0 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KZN89075.1 - 1.3e-18 67.2 0.0 4.8e-18 65.4 0.0 2.0 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Arb2 PF09757.9 KZN89076.1 - 5.8e-95 317.3 0.2 7.6e-95 316.9 0.2 1.1 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 KZN89076.1 - 9.2e-76 255.2 0.0 1.5e-75 254.6 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Bys1 PF04681.12 KZN89077.1 - 2.7e-15 56.6 1.4 3.3e-15 56.4 1.4 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Thermopsin PF05317.11 KZN89077.1 - 0.055 12.9 0.0 0.062 12.8 0.0 1.1 1 0 0 1 1 1 0 Thermopsin Peptidase_M16_M PF16187.5 KZN89078.1 - 5.7e-98 327.6 1.3 1e-97 326.8 1.3 1.5 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 KZN89078.1 - 2e-34 119.2 0.4 1.8e-21 77.0 0.0 4.5 5 0 0 5 5 5 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KZN89078.1 - 5.4e-32 110.8 6.2 6.9e-31 107.2 2.5 3.8 2 2 1 3 3 3 1 Insulinase (Peptidase family M16) Phage_int_SAM_1 PF02899.17 KZN89078.1 - 0.0032 17.7 1.8 1.1 9.7 0.2 3.8 3 0 0 3 3 3 1 Phage integrase, N-terminal SAM-like domain DUF3208 PF11482.8 KZN89078.1 - 0.022 15.0 0.3 0.11 12.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3208) Bac_thur_toxin PF01338.18 KZN89078.1 - 0.04 13.4 0.1 4.3 6.7 0.0 3.0 3 0 0 3 3 3 0 Bacillus thuringiensis toxin NUDIX_2 PF13869.6 KZN89079.1 - 3.1e-81 271.5 0.0 3.7e-81 271.2 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Lipase_3 PF01764.25 KZN89080.1 - 2.5e-36 124.6 0.0 3.8e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 KZN89080.1 - 5.5e-07 29.5 0.1 1.2e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 Lipase 3 N-terminal region Hydrolase_4 PF12146.8 KZN89080.1 - 8.1e-06 25.3 0.0 1.6e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 KZN89080.1 - 8.8e-05 22.2 0.1 0.00038 20.1 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase Thioesterase PF00975.20 KZN89080.1 - 0.00093 19.4 0.0 0.0014 18.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KZN89080.1 - 0.0031 18.1 0.2 0.0059 17.2 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 KZN89080.1 - 0.042 13.4 0.0 0.08 12.5 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) DUF3431 PF11913.8 KZN89081.1 - 2.1e-89 298.9 0.2 5.4e-89 297.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3431) CoaE PF01121.20 KZN89082.1 - 9.6e-42 142.7 0.0 1.4e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 KZN89082.1 - 0.0059 17.2 0.2 0.47 11.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain 2TM PF13239.6 KZN89082.1 - 0.087 13.1 0.3 0.17 12.2 0.3 1.5 1 0 0 1 1 1 0 2TM domain zf-Di19 PF05605.12 KZN89084.1 - 0.0041 17.4 6.7 0.1 12.9 1.4 2.7 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding MMADHC PF10229.9 KZN89084.1 - 0.085 12.6 1.9 0.14 11.9 1.9 1.2 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type D protein Phage_Gp23 PF10669.9 KZN89084.1 - 0.3 11.4 9.2 0.82 10.0 9.2 1.7 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) zf-C2H2_4 PF13894.6 KZN89084.1 - 1.9 9.5 10.1 9.1 7.4 0.1 4.1 3 0 0 3 3 3 0 C2H2-type zinc finger MPP6 PF10175.9 KZN89085.1 - 5.4e-07 30.2 17.2 7.6e-05 23.2 17.2 2.7 1 1 0 1 1 1 1 M-phase phosphoprotein 6 Myc_N PF01056.18 KZN89085.1 - 0.055 13.4 10.8 0.069 13.0 10.8 1.1 1 0 0 1 1 1 0 Myc amino-terminal region DUF3602 PF12223.8 KZN89085.1 - 5.9 7.6 8.5 0.64 10.7 2.3 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF3602) zf-CHCC PF10276.9 KZN89086.1 - 1e-17 63.8 0.5 1.8e-17 63.1 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger domain UPF0047 PF01894.17 KZN89087.1 - 1.8e-37 128.0 0.0 2.1e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 TRI5 PF06330.11 KZN89088.1 - 1.3e-31 109.8 0.6 1.8e-31 109.3 0.6 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) GerD PF17898.1 KZN89088.1 - 0.013 15.5 0.0 0.066 13.2 0.0 1.9 2 0 0 2 2 2 0 Spore germination GerD central core domain Lactamase_B PF00753.27 KZN89089.1 - 5.1e-18 65.8 2.2 6.7e-18 65.4 2.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KZN89089.1 - 2.2e-05 24.1 0.2 4.6e-05 23.0 0.2 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Glyco_hydro_32N PF00251.20 KZN89090.1 - 7.8e-92 308.1 2.4 9.8e-92 307.8 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KZN89090.1 - 8.6e-30 103.8 0.9 1.5e-29 103.0 0.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Sortilin-Vps10 PF15902.5 KZN89090.1 - 0.0039 16.0 0.3 0.013 14.3 0.0 1.9 2 0 0 2 2 2 1 Sortilin, neurotensin receptor 3, CHB_HEX_C PF03174.13 KZN89090.1 - 0.016 15.2 0.1 0.049 13.6 0.1 1.8 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain BNR PF02012.20 KZN89090.1 - 0.093 12.8 0.3 0.86 9.9 0.1 2.9 2 0 0 2 2 2 0 BNR/Asp-box repeat Fungal_trans PF04082.18 KZN89091.1 - 4e-07 29.3 0.0 7e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NPP1 PF05630.11 KZN89092.1 - 0.00019 21.6 2.2 0.0013 18.9 0.2 2.0 1 1 1 2 2 2 1 Necrosis inducing protein (NPP1) GFA PF04828.14 KZN89093.1 - 1.8e-09 37.8 2.3 2.9e-09 37.1 2.3 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme F-box-like PF12937.7 KZN89094.1 - 7.3e-05 22.6 0.1 0.00021 21.1 0.1 1.8 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KZN89094.1 - 0.057 13.9 1.9 4 8.0 0.1 3.8 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) DUF3431 PF11913.8 KZN89095.1 - 8.3e-82 274.1 0.1 9.9e-82 273.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) WXG100 PF06013.12 KZN89096.1 - 4.4e-09 36.4 7.9 5.4e-09 36.2 7.9 1.1 1 0 0 1 1 1 1 Proteins of 100 residues with WXG T7SS_ESX_EspC PF10824.8 KZN89096.1 - 4e-06 27.2 3.3 6.3e-06 26.6 3.3 1.3 1 0 0 1 1 1 1 Excreted virulence factor EspC, type VII ESX diderm MCPsignal PF00015.21 KZN89096.1 - 0.0012 18.7 0.3 0.0018 18.1 0.3 1.2 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain RmuC PF02646.16 KZN89096.1 - 0.0069 15.6 0.7 0.071 12.2 0.2 1.9 1 1 1 2 2 2 1 RmuC family Baculo_PEP_C PF04513.12 KZN89096.1 - 0.011 15.8 0.3 0.013 15.5 0.3 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 KZN89096.1 - 0.022 15.0 0.8 0.13 12.6 0.2 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF5344 PF17279.2 KZN89096.1 - 0.06 13.9 1.9 0.27 11.9 2.0 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5344) DUF4164 PF13747.6 KZN89096.1 - 0.089 13.1 0.4 0.12 12.7 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) NPV_P10 PF05531.12 KZN89096.1 - 0.1 13.1 1.7 0.87 10.1 1.4 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF4618 PF15397.6 KZN89096.1 - 0.14 11.5 0.2 0.31 10.4 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) AI-2E_transport PF01594.16 KZN89096.1 - 0.27 10.3 0.1 0.31 10.1 0.1 1.1 1 0 0 1 1 1 0 AI-2E family transporter ApoLp-III PF07464.11 KZN89096.1 - 0.35 11.0 4.6 1.6 8.8 4.4 1.8 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) EspB_PE PF18625.1 KZN89096.1 - 0.8 10.2 6.8 3.8 8.0 6.7 1.9 1 1 0 1 1 1 0 ESX-1 secreted protein B PE domain Melibiase_2 PF16499.5 KZN89098.1 - 5.7e-55 186.5 7.3 2.6e-37 128.6 0.7 2.3 2 0 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 KZN89098.1 - 1.3e-12 47.5 0.5 1.3e-12 47.5 0.5 2.7 3 0 0 3 3 3 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KZN89098.1 - 6.4e-08 31.9 0.0 1.3e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Melibiase PQQ_3 PF13570.6 KZN89099.1 - 9.9 6.8 7.8 1.1 9.9 0.9 3.0 3 0 0 3 3 3 0 PQQ-like domain zf-CHY PF05495.12 KZN89100.1 - 1.8e-11 44.4 22.2 3.3e-11 43.5 22.2 1.4 1 0 0 1 1 1 1 CHY zinc finger C1_4 PF07975.12 KZN89100.1 - 0.77 10.0 16.0 5 7.4 0.4 2.8 1 1 2 3 3 3 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.10 KZN89100.1 - 3.1 8.0 16.9 2.5 8.3 8.7 2.4 1 1 1 2 2 2 0 Zinc ribbon domain Proteasome PF00227.26 KZN89101.1 - 1.2e-54 184.7 0.1 1.6e-54 184.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KZN89101.1 - 7.6e-08 31.9 1.1 2.5e-07 30.2 0.0 2.4 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.12 KZN89101.1 - 0.025 14.5 0.1 0.054 13.4 0.1 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) DUF4707 PF15806.5 KZN89101.1 - 0.11 11.4 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4707) zf-RanBP PF00641.18 KZN89102.1 - 1.2e-20 72.4 9.1 7.8e-11 41.1 1.5 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 KZN89102.1 - 5.6e-08 32.5 0.0 1.9e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 KZN89102.1 - 2.2e-06 28.3 0.0 3.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Exonuclease zf-ribbon_3 PF13248.6 KZN89102.1 - 0.21 11.0 2.4 2.5 7.6 0.3 2.7 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 KZN89102.1 - 0.57 10.3 5.0 2.9 8.0 0.4 2.4 2 0 0 2 2 2 0 Double zinc ribbon Cnd3 PF12719.7 KZN89103.1 - 3.7e-89 298.8 0.1 2.6e-88 296.0 0.0 2.3 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KZN89103.1 - 5.1e-06 26.8 8.1 5.9e-05 23.4 0.6 3.5 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 KZN89103.1 - 9.1e-05 22.4 11.1 0.081 13.2 0.0 5.7 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 KZN89103.1 - 0.0024 18.0 1.1 0.15 12.0 0.1 3.2 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KZN89103.1 - 0.025 15.1 3.3 2.5 8.7 0.1 4.5 4 1 1 5 5 5 0 HEAT-like repeat DUF4521 PF15021.6 KZN89103.1 - 0.075 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) LID PF17916.1 KZN89103.1 - 1.1 9.0 5.5 0.8 9.4 0.2 3.1 3 0 0 3 3 3 0 LIM interaction domain (LID) PALP PF00291.25 KZN89104.1 - 3.4e-68 230.2 0.2 4e-68 230.0 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Tim17 PF02466.19 KZN89105.1 - 2.9e-40 137.1 6.9 4.1e-40 136.6 6.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4048 PF13257.6 KZN89106.1 - 4.4e-85 285.6 23.5 4.4e-85 285.6 23.5 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF4048) Bap31_Bap29_C PF18035.1 KZN89106.1 - 0.038 14.0 0.3 0.079 13.0 0.3 1.5 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain TMEM61 PF15105.6 KZN89106.1 - 0.14 12.0 1.7 3.4 7.5 0.6 2.5 2 0 0 2 2 2 0 TMEM61 protein family E3_UbLigase_EDD PF11547.8 KZN89106.1 - 0.16 11.7 0.0 0.46 10.2 0.0 1.8 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD ADIP PF11559.8 KZN89106.1 - 4 7.5 7.0 0.17 12.0 1.0 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Pkinase PF00069.25 KZN89107.1 - 3.1e-06 26.7 0.0 4.1e-05 23.1 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain APH PF01636.23 KZN89108.1 - 3.2e-13 50.2 0.0 6.8e-13 49.1 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN89108.1 - 2.6e-05 23.9 0.1 0.00012 21.8 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.25 KZN89109.1 - 6e-70 235.6 0.0 7.8e-70 235.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN89109.1 - 4.7e-47 160.4 0.0 6.8e-47 159.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KZN89109.1 - 6e-05 22.0 0.0 0.00011 21.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KZN89109.1 - 0.00018 21.0 0.0 0.0018 17.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like ABC1 PF03109.16 KZN89109.1 - 0.13 12.4 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 ABC1 family FAD-oxidase_C PF02913.19 KZN89110.1 - 2.9e-60 204.0 0.0 5.4e-60 203.1 0.0 1.5 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KZN89110.1 - 3.8e-36 123.9 0.3 7.1e-36 123.0 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain RmlD_sub_bind PF04321.17 KZN89111.1 - 1.4e-57 195.0 0.0 1.7e-57 194.7 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KZN89111.1 - 1.3e-24 87.0 0.0 2.7e-24 86.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KZN89111.1 - 2e-11 43.6 0.1 2.7e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 KZN89111.1 - 5.2e-11 42.1 0.1 9.3e-10 38.0 0.1 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KZN89111.1 - 2.4e-10 40.0 0.1 4.2e-08 32.7 0.0 2.9 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KZN89111.1 - 1.2e-09 38.0 0.1 1.1e-08 34.8 0.1 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KZN89111.1 - 0.15 12.0 0.0 22 4.9 0.1 2.6 3 0 0 3 3 3 0 KR domain PH PF00169.29 KZN89112.1 - 6.1e-06 26.7 1.4 1.4e-05 25.5 1.4 1.5 1 0 0 1 1 1 1 PH domain RA PF00788.23 KZN89112.1 - 0.00031 21.3 0.0 0.0013 19.3 0.0 2.0 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain TUG-UBL1 PF11470.8 KZN89112.1 - 0.0071 16.5 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 TUG ubiquitin-like domain CNPase PF05881.12 KZN89114.1 - 0.043 13.4 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) TrkH PF02386.16 KZN89115.1 - 7.6e-149 496.4 5.5 7.6e-149 496.4 5.5 2.0 2 0 0 2 2 2 2 Cation transport protein DUF1289 PF06945.13 KZN89116.1 - 0.025 14.4 0.2 0.07 12.9 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) ADH_N PF08240.12 KZN89117.1 - 0.0014 18.5 0.0 0.0045 16.9 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN89117.1 - 0.043 13.8 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KZN89117.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase CN_hydrolase PF00795.22 KZN89118.1 - 6.2e-22 78.2 0.0 9.6e-22 77.6 0.0 1.3 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Poxvirus_B22R_C PF13168.6 KZN89119.1 - 0.054 13.0 0.0 5 6.6 0.0 2.8 3 0 0 3 3 3 0 Poxvirus B22R protein C-terminal Dynamin_M PF01031.20 KZN89120.1 - 1e-101 339.9 0.2 1e-101 339.9 0.2 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KZN89120.1 - 1.7e-56 190.9 0.1 3.6e-56 189.8 0.1 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KZN89120.1 - 1.2e-30 105.5 4.3 1.2e-30 105.5 4.3 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KZN89120.1 - 1.8e-05 24.8 0.4 0.00016 21.7 0.4 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SdiA-regulated PF06977.11 KZN89120.1 - 0.041 13.1 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 SdiA-regulated Thioredoxin_14 PF18402.1 KZN89120.1 - 0.088 12.7 0.3 0.89 9.5 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like domain AAA_15 PF13175.6 KZN89120.1 - 0.092 12.4 2.6 4.6 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain ATP-synt_ab PF00006.25 KZN89121.1 - 2.4e-110 367.2 0.0 3.6e-110 366.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KZN89121.1 - 5e-46 155.5 0.0 9.2e-46 154.6 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KZN89121.1 - 8.2e-16 58.3 0.8 1.7e-15 57.3 0.8 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 KZN89121.1 - 0.051 12.8 0.0 1.7 7.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain LPD23 PF18838.1 KZN89121.1 - 0.16 11.7 0.1 0.33 10.7 0.1 1.5 1 0 0 1 1 1 0 Large polyvalent protein associated domain 23 DUF2236 PF09995.9 KZN89123.1 - 1e-29 104.4 0.0 1.5e-29 103.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) HTH_8 PF02954.19 KZN89123.1 - 0.058 13.2 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_20 PF12840.7 KZN89123.1 - 0.099 12.7 0.2 2.4 8.3 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HHH_5 PF14520.6 KZN89123.1 - 0.12 13.0 0.1 22 5.7 0.0 3.0 3 0 0 3 3 3 0 Helix-hairpin-helix domain HpcH_HpaI PF03328.14 KZN89124.1 - 2.2e-35 121.8 0.0 2.7e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Mem_trans PF03547.18 KZN89125.1 - 1.5e-14 53.2 8.0 6.8e-12 44.5 0.1 2.1 2 0 0 2 2 2 2 Membrane transport protein ketoacyl-synt PF00109.26 KZN89126.1 - 1.2e-66 224.9 0.1 1.9e-66 224.2 0.1 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KZN89126.1 - 8.1e-63 212.4 0.0 1.2e-62 211.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KZN89126.1 - 1.5e-58 197.6 0.0 3.6e-58 196.5 0.0 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KZN89126.1 - 3.2e-56 191.2 0.0 5.3e-56 190.5 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KZN89126.1 - 9.1e-32 109.5 0.1 2e-31 108.5 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KZN89126.1 - 8.6e-24 84.2 0.1 3e-23 82.4 0.0 2.0 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 KZN89126.1 - 9e-22 77.7 0.0 4e-21 75.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N PF00107.26 KZN89126.1 - 3.2e-17 62.7 0.0 2.3e-16 60.0 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KZN89126.1 - 1.7e-14 55.0 0.0 7.6e-13 49.7 0.0 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 KZN89126.1 - 2.3e-12 47.1 0.0 6.2e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN89126.1 - 2.6e-12 47.3 0.0 9e-12 45.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KZN89126.1 - 7.1e-11 41.9 0.0 4e-08 32.9 0.0 3.2 2 1 1 3 3 3 1 short chain dehydrogenase Methyltransf_11 PF08241.12 KZN89126.1 - 1.3e-10 41.8 0.0 3.5e-10 40.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN89126.1 - 4.1e-10 39.7 0.0 8.9e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KZN89126.1 - 7.5e-07 28.9 0.0 7e-06 25.8 0.0 2.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 KZN89126.1 - 6.7e-06 26.4 0.0 1.8e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 KZN89126.1 - 1.7e-05 24.7 0.0 4.6e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 KZN89126.1 - 7.7e-05 22.2 2.5 0.00014 21.3 0.3 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain SAT PF16073.5 KZN89126.1 - 0.00044 20.1 0.1 0.92 9.2 0.0 2.7 2 0 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Ubie_methyltran PF01209.18 KZN89126.1 - 0.0028 17.1 0.0 0.0094 15.3 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 KZN89126.1 - 0.0096 15.5 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) ACP_syn_III PF08545.10 KZN89126.1 - 0.034 14.0 1.0 0.085 12.7 1.0 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_16 PF10294.9 KZN89126.1 - 0.17 11.6 0.0 0.57 9.9 0.0 1.8 1 0 0 1 1 1 0 Lysine methyltransferase WD40 PF00400.32 KZN89127.1 - 1.2e-18 67.1 13.8 0.0018 19.0 0.3 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN89127.1 - 4.7e-10 39.6 6.3 0.068 13.5 0.1 5.6 1 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KZN89127.1 - 0.0012 17.9 2.3 0.91 8.4 0.1 3.3 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein CLTH PF10607.9 KZN89127.1 - 0.0017 18.2 0.3 0.0035 17.3 0.3 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Nup160 PF11715.8 KZN89127.1 - 0.0033 16.2 0.1 0.008 14.9 0.1 1.6 2 0 0 2 2 2 1 Nucleoporin Nup120/160 WD40_3 PF15911.5 KZN89127.1 - 0.013 15.4 0.1 0.58 10.2 0.0 2.4 2 0 0 2 2 2 0 WD domain, G-beta repeat DEAD PF00270.29 KZN89128.1 - 2.8e-41 141.2 0.2 4.9e-41 140.4 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KZN89128.1 - 1.6e-33 115.3 0.1 6.6e-33 113.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KZN89128.1 - 0.0011 18.7 0.1 0.0017 18.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KZN89128.1 - 0.0046 17.0 0.0 0.009 16.0 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KZN89128.1 - 0.0088 16.4 0.1 0.074 13.4 0.1 2.2 2 0 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.14 KZN89128.1 - 0.056 13.4 0.5 0.2 11.6 0.0 2.1 2 0 0 2 2 2 0 Flavivirus DEAD domain TniB PF05621.11 KZN89128.1 - 0.089 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Helicase_RecD PF05127.14 KZN89128.1 - 0.091 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 KZN89128.1 - 0.18 12.1 0.6 0.73 10.1 0.6 1.9 1 1 0 1 1 1 0 AAA domain DUF3449 PF11931.8 KZN89129.1 - 3.3e-73 245.4 0.4 7.1e-73 244.3 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KZN89129.1 - 9.7e-26 90.1 1.6 2.2e-25 88.9 0.1 2.2 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 KZN89129.1 - 4.7e-16 58.3 1.0 1.3e-15 57.0 1.0 1.8 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.8 KZN89129.1 - 1.4e-08 34.8 2.6 5.4e-07 29.7 0.4 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KZN89129.1 - 1.2e-07 31.9 2.0 2.8e-06 27.5 0.5 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP9_N PF16958.5 KZN89129.1 - 1.7e-05 24.9 13.8 0.00054 20.0 3.2 3.0 2 1 1 3 3 3 2 Pre-mRNA-splicing factor PRP9 N-terminus zf-C2H2_2 PF12756.7 KZN89129.1 - 0.0015 18.8 0.5 0.019 15.3 0.0 2.5 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) CmlA_N PF18456.1 KZN89129.1 - 0.019 14.3 0.1 0.044 13.1 0.1 1.5 1 0 0 1 1 1 0 Diiron non-heme beta-hydroxylase N-terminal domain zf-C4H2 PF10146.9 KZN89129.1 - 0.058 13.7 1.4 0.077 13.3 0.0 1.9 2 0 0 2 2 2 0 Zinc finger-containing protein zf-C2H2_4 PF13894.6 KZN89129.1 - 0.23 12.4 1.2 42 5.4 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger DNA_ligase_A_M PF01068.21 KZN89130.1 - 4.9e-23 81.8 0.0 1.4e-22 80.4 0.0 1.7 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KZN89130.1 - 3.8e-16 59.9 0.0 6.6e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 DNA ligase N terminus Myf5 PF12232.8 KZN89130.1 - 0.064 14.0 1.4 0.24 12.2 1.4 2.0 1 0 0 1 1 1 0 Myogenic determination factor 5 GEN1_C PF18380.1 KZN89130.1 - 0.11 13.3 1.1 13 6.7 0.1 2.6 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain ANAPC8 PF04049.13 KZN89131.1 - 8.4e-53 178.2 0.0 2.3e-52 176.7 0.0 1.8 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.6 KZN89131.1 - 3.5e-22 76.7 15.9 8e-05 22.6 0.0 9.7 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 KZN89131.1 - 4.7e-22 76.8 7.6 0.00042 20.0 0.0 8.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 KZN89131.1 - 4e-18 64.0 18.5 0.063 13.4 2.8 9.7 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 KZN89131.1 - 1e-13 50.9 18.9 0.0084 16.9 0.0 8.9 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 KZN89131.1 - 1.1e-11 44.2 1.6 2e-06 27.4 0.1 4.5 2 2 2 4 4 4 3 TPR repeat TPR_12 PF13424.6 KZN89131.1 - 7.1e-11 42.2 5.9 0.34 11.2 0.1 6.3 5 2 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KZN89131.1 - 1.3e-10 41.7 12.8 7e-05 23.4 0.0 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KZN89131.1 - 1.3e-10 41.3 16.1 0.082 13.1 0.2 6.4 7 0 0 7 7 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KZN89131.1 - 2.1e-09 37.1 3.6 1.8 9.1 0.0 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 KZN89131.1 - 3e-09 36.9 10.1 0.00013 22.1 0.2 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KZN89131.1 - 1.3e-08 34.3 6.4 0.31 11.2 0.2 6.4 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KZN89131.1 - 2.9e-08 34.1 15.0 0.12 12.9 0.1 8.0 9 1 1 10 10 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 KZN89131.1 - 3.2e-05 24.3 19.7 1.9 9.3 0.4 8.7 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 KZN89131.1 - 0.0027 17.0 3.5 0.0027 17.0 3.5 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat ChAPs PF09295.10 KZN89131.1 - 0.0064 15.5 0.1 5.9 5.8 0.0 3.0 2 1 1 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) HrpB1_HrpK PF09613.10 KZN89131.1 - 0.0092 15.6 0.1 0.044 13.4 0.0 2.1 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_10 PF13374.6 KZN89131.1 - 0.19 11.6 14.2 3.3 7.7 0.5 6.5 6 1 1 7 7 7 0 Tetratricopeptide repeat PPR PF01535.20 KZN89131.1 - 0.4 11.0 1.4 46 4.6 0.0 4.2 5 0 0 5 5 4 0 PPR repeat polyprenyl_synt PF00348.17 KZN89132.1 - 2.2e-88 295.6 0.0 2.8e-88 295.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase RNase_H2-Ydr279 PF09468.10 KZN89132.1 - 0.0058 16.8 0.3 0.028 14.6 0.1 2.0 2 1 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain GatB_Yqey PF02637.18 KZN89132.1 - 0.11 12.3 1.7 0.32 10.9 1.7 1.8 1 0 0 1 1 1 0 GatB domain PHO4 PF01384.20 KZN89133.1 - 1.2e-108 363.2 11.6 1.4e-108 363.0 11.6 1.0 1 0 0 1 1 1 1 Phosphate transporter family Glycophorin_A PF01102.18 KZN89133.1 - 0.0015 18.7 0.4 0.0062 16.8 0.1 2.1 2 0 0 2 2 2 1 Glycophorin A Tim17 PF02466.19 KZN89133.1 - 0.01 16.2 0.8 0.085 13.2 0.8 2.8 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Deltameth_res PF16020.5 KZN89133.1 - 0.46 10.4 2.1 3.6 7.5 0.9 2.9 2 0 0 2 2 2 0 Deltamethrin resistance ParA PF10609.9 KZN89134.1 - 1.5e-84 283.3 0.1 3.3e-83 278.9 0.1 2.0 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KZN89134.1 - 5.9e-10 39.3 0.0 3.7e-09 36.7 0.0 2.0 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 KZN89134.1 - 1.1e-06 28.2 0.0 4.8e-06 26.1 0.0 1.8 1 1 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 KZN89134.1 - 1.3e-05 25.2 0.3 0.00025 21.0 0.3 2.1 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 KZN89134.1 - 0.00022 20.5 0.8 0.00037 19.8 0.8 1.3 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_25 PF13481.6 KZN89134.1 - 0.00074 19.1 0.2 0.0014 18.3 0.2 1.4 1 0 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 KZN89134.1 - 0.0025 17.4 0.6 0.012 15.2 0.6 2.0 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_26 PF13500.6 KZN89134.1 - 0.0031 17.4 1.0 2.3 8.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 KZN89134.1 - 0.0058 15.7 0.5 0.0087 15.1 0.5 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 KZN89134.1 - 0.071 13.0 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase Fer4_NifH PF00142.18 KZN89134.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RsgA_GTPase PF03193.16 KZN89134.1 - 0.8 9.6 2.0 1.5 8.7 2.0 1.4 1 0 0 1 1 1 0 RsgA GTPase SEP PF08059.13 KZN89135.1 - 3.5e-25 88.4 0.1 6.4e-25 87.5 0.1 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 KZN89135.1 - 2.4e-13 50.1 0.0 4e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 KZN89135.1 - 2.4e-12 46.5 3.0 4e-12 45.8 3.0 1.4 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 KZN89135.1 - 0.00072 19.1 0.2 0.0012 18.5 0.2 1.3 1 0 0 1 1 1 1 TAP C-terminal domain DASH_Ask1 PF08655.10 KZN89137.1 - 0.028 14.3 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Ask1 Asp_protease_2 PF13650.6 KZN89137.1 - 0.15 12.7 0.0 0.58 10.8 0.0 2.0 2 0 0 2 2 2 0 Aspartyl protease Fungal_trans PF04082.18 KZN89138.1 - 4.3e-10 39.1 0.6 6.9e-10 38.4 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN89138.1 - 4.1e-06 26.8 12.0 7.3e-06 26.0 12.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DJ-1_PfpI PF01965.24 KZN89139.1 - 1e-09 38.4 0.0 7e-09 35.7 0.0 2.1 1 1 1 2 2 2 1 DJ-1/PfpI family ThiJ_like PF17124.5 KZN89139.1 - 0.014 15.0 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 ThiJ/PfpI family-like DIT1_PvcA PF05141.12 KZN89140.1 - 1.1e-91 307.2 0.0 1.6e-91 306.6 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.16 KZN89140.1 - 1.1e-21 77.8 0.0 4.1e-21 76.0 0.0 1.8 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family bZIP_1 PF00170.21 KZN89141.1 - 0.0068 16.5 8.2 0.0098 16.0 8.2 1.2 1 0 0 1 1 1 1 bZIP transcription factor DUF4149 PF13664.6 KZN89142.1 - 3.1e-21 75.6 0.8 3.1e-21 75.6 0.8 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) p450 PF00067.22 KZN89143.1 - 2.8e-47 161.5 0.0 3.6e-47 161.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF572 PF04502.13 KZN89144.1 - 9.1e-61 206.3 19.3 1.1e-60 206.1 19.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) HypA PF01155.19 KZN89144.1 - 0.043 13.8 1.2 1.3 9.1 0.0 2.7 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Fib_alpha PF08702.10 KZN89144.1 - 0.065 13.4 3.8 0.078 13.2 2.9 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Zn-ribbon_8 PF09723.10 KZN89144.1 - 1.9 8.7 6.4 87 3.4 0.1 3.4 2 1 1 3 3 3 0 Zinc ribbon domain MDM10 PF12519.8 KZN89144.1 - 3 6.6 4.8 4.3 6.1 4.8 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 TPR_1 PF00515.28 KZN89145.1 - 8.5e-29 98.2 0.5 0.00044 19.9 0.3 10.0 9 0 0 9 9 9 7 Tetratricopeptide repeat ANAPC3 PF12895.7 KZN89145.1 - 2.5e-28 98.1 10.9 4.8e-22 78.0 0.6 5.7 6 0 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KZN89145.1 - 4.9e-28 94.9 11.0 0.0062 16.6 0.0 10.6 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_19 PF14559.6 KZN89145.1 - 3.9e-21 75.3 8.4 0.00045 20.7 0.0 7.9 6 3 3 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 KZN89145.1 - 2.6e-17 62.8 19.4 3.3e-07 30.5 0.1 9.2 7 3 2 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 KZN89145.1 - 7.3e-15 53.9 0.2 0.53 10.6 0.1 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 KZN89145.1 - 6.7e-14 51.4 15.1 2.4 9.2 0.3 10.3 8 3 3 11 11 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 KZN89145.1 - 7e-12 45.8 22.4 0.51 11.0 1.3 9.0 8 1 2 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.6 KZN89145.1 - 2.5e-10 39.9 1.8 0.38 10.5 0.1 8.5 9 0 0 9 9 9 2 TPR repeat TPR_7 PF13176.6 KZN89145.1 - 4.1e-10 39.0 17.2 0.043 13.9 0.0 9.8 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_6 PF13174.6 KZN89145.1 - 4.4e-09 36.4 9.1 1.4 9.7 0.2 8.0 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 KZN89145.1 - 1.3e-06 28.1 23.5 0.00061 19.6 0.1 8.5 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_17 PF13431.6 KZN89145.1 - 2.5e-05 24.4 1.4 5 7.7 0.0 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_21 PF09976.9 KZN89145.1 - 0.0051 16.5 1.6 6.8 6.4 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 KZN89145.1 - 0.0059 17.1 17.2 18 6.4 0.1 8.0 8 0 0 8 8 6 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KZN89145.1 - 0.009 16.0 0.1 0.2 11.7 0.0 2.7 2 0 0 2 2 2 1 Putative TPR-like repeat TPR_3 PF07720.12 KZN89145.1 - 0.56 10.3 5.9 2 8.5 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 KZN89145.1 - 2.5 8.3 13.5 17 5.7 0.1 6.1 5 2 1 6 6 6 0 Tetratricopeptide repeat Glyco_transf_90 PF05686.12 KZN89146.1 - 2.3e-29 102.5 0.2 3.1e-29 102.1 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 FAT PF02259.23 KZN89147.1 - 5.2e-73 246.2 9.8 1.5e-72 244.7 8.9 2.2 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KZN89147.1 - 1e-34 120.5 0.2 2.4e-34 119.3 0.2 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KZN89147.1 - 1.7e-05 24.5 0.1 5e-05 23.0 0.1 1.9 1 0 0 1 1 1 1 FATC domain FANCI_S2 PF14676.6 KZN89147.1 - 0.7 10.2 2.6 5.4 7.3 0.0 3.9 5 0 0 5 5 5 0 FANCI solenoid 2 Ndc1_Nup PF09531.10 KZN89147.1 - 1.4 7.5 9.4 4.6 5.8 9.4 1.9 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MFS_1 PF07690.16 KZN89150.1 - 4e-43 147.7 43.1 4e-43 147.7 43.1 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KZN89150.1 - 4.9e-11 41.8 21.6 6.9e-11 41.3 21.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KZN89150.1 - 7.5e-11 41.5 19.2 1.2e-07 31.0 7.8 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter Trp_DMAT PF11991.8 KZN89151.1 - 5.7e-95 318.8 0.0 6.6e-95 318.6 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Methyltransf_25 PF13649.6 KZN89152.1 - 2.2e-13 50.7 0.0 4.5e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN89152.1 - 2.6e-12 47.2 0.0 5.4e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KZN89152.1 - 4.7e-09 35.9 0.0 1.4e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KZN89152.1 - 1.6e-08 34.6 0.0 2.6e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN89152.1 - 8.5e-08 32.9 0.0 1.4e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN89152.1 - 1.4e-07 31.4 0.0 2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF5442 PF17514.2 KZN89152.1 - 0.099 12.8 0.0 1.9 8.8 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5442) MTS PF05175.14 KZN89152.1 - 0.16 11.6 0.0 0.38 10.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain p450 PF00067.22 KZN89153.1 - 2.3e-39 135.5 0.3 3.1e-39 135.0 0.3 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 KZN89154.1 - 1.9e-14 53.7 8.1 3.7e-13 49.4 8.1 2.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KZN89154.1 - 5.9e-07 29.4 8.0 3.5e-05 23.5 0.1 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KZN89154.1 - 7e-05 22.1 4.8 0.00099 18.3 1.9 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KZN89154.1 - 0.002 17.4 0.4 0.3 10.3 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KZN89154.1 - 0.0043 15.8 1.8 0.12 11.0 0.6 2.8 3 0 0 3 3 3 1 HI0933-like protein Lycopene_cycl PF05834.12 KZN89154.1 - 0.011 14.8 3.1 0.094 11.7 3.1 2.2 1 1 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KZN89154.1 - 0.096 12.0 0.4 0.2 10.9 0.4 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain p450 PF00067.22 KZN89155.1 - 4.8e-42 144.3 0.0 6.5e-42 143.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 KZN89156.1 - 1.8e-144 481.5 0.0 1e-71 241.7 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KZN89156.1 - 1.8e-79 267.5 0.0 1.7e-44 152.3 0.0 3.8 2 2 0 2 2 2 2 Condensation domain PP-binding PF00550.25 KZN89156.1 - 9.9e-22 77.1 0.0 3.6e-10 40.1 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KZN89156.1 - 1.7e-10 41.7 0.0 5.8e-05 24.0 0.0 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain B56 PF01603.20 KZN89157.1 - 2.3e-192 639.5 4.4 2.8e-192 639.3 4.4 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 KZN89157.1 - 0.0056 16.6 0.8 0.91 9.4 0.0 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF3016 PF11454.8 KZN89158.1 - 0.077 12.8 0.0 0.099 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) Tau95 PF09734.9 KZN89160.1 - 1.1e-40 139.6 0.2 1.1e-40 139.6 0.2 1.6 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KZN89160.1 - 1.7e-34 118.8 0.0 2.6e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 Tau95 Triple barrel domain Pro-MCH PF05824.12 KZN89161.1 - 0.27 11.2 0.8 0.7 9.9 0.1 2.0 2 0 0 2 2 2 0 Pro-melanin-concentrating hormone (Pro-MCH) PfkB PF00294.24 KZN89162.1 - 1e-32 113.7 0.0 1.8e-32 112.8 0.0 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase p6 PF17548.2 KZN89162.1 - 0.026 14.5 0.0 0.091 12.7 0.0 1.8 2 0 0 2 2 2 0 Histone-like Protein p6 RNase_H PF00075.24 KZN89163.1 - 0.0017 18.5 0.0 0.0037 17.4 0.0 1.8 1 1 0 1 1 1 1 RNase H CVNH PF08881.10 KZN89167.1 - 6.1e-28 97.5 0.2 7e-28 97.3 0.2 1.0 1 0 0 1 1 1 1 CVNH domain FWWh PF14922.6 KZN89168.1 - 0.031 14.2 0.0 0.053 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function MCM PF00493.23 KZN89169.1 - 6.4e-104 345.9 0.0 1.2e-103 345.1 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KZN89169.1 - 4.6e-36 123.4 0.4 9.4e-36 122.4 0.4 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KZN89169.1 - 1.9e-29 101.9 1.9 4.8e-29 100.6 1.9 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KZN89169.1 - 4.6e-15 56.1 0.2 1.3e-14 54.7 0.2 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KZN89169.1 - 3.7e-06 26.5 0.0 0.00086 18.7 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KZN89169.1 - 4.1e-05 23.6 0.0 8.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KZN89169.1 - 0.0003 20.7 0.0 0.001 18.9 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KZN89169.1 - 0.067 12.9 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 KZN89169.1 - 0.078 13.4 0.1 0.3 11.5 0.0 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Imm35 PF15567.6 KZN89169.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 35 TTC5_OB PF16669.5 KZN89169.1 - 0.12 12.0 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat protein 5 OB fold domain Mg_chelatase_C PF13335.6 KZN89169.1 - 0.19 12.4 0.8 0.55 10.9 0.3 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal Vps54 PF07928.12 KZN89170.1 - 8e-51 172.0 0.8 4.1e-50 169.7 0.1 2.5 2 0 0 2 2 2 1 Vps54-like protein Vps54_N PF10475.9 KZN89170.1 - 1.1e-06 28.1 0.2 3.4e-06 26.6 0.2 1.7 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KZN89170.1 - 0.00011 22.1 0.2 0.00028 20.7 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Na_trans_cytopl PF11933.8 KZN89170.1 - 0.0036 17.1 1.0 0.015 15.1 1.0 2.0 1 0 0 1 1 1 1 Cytoplasmic domain of voltage-gated Na+ ion channel Laminin_II PF06009.12 KZN89170.1 - 3.7 7.6 6.0 6.4 6.8 0.4 3.0 2 1 0 2 2 2 0 Laminin Domain II Glycogen_syn PF05693.13 KZN89173.1 - 0 1148.8 0.0 0 1148.6 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_4 PF13439.6 KZN89173.1 - 3e-05 24.1 0.5 8.3e-05 22.6 0.5 1.8 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KZN89173.1 - 3.1e-05 24.4 0.0 0.014 15.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KZN89173.1 - 0.00012 22.5 0.1 0.0003 21.3 0.1 1.8 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.20 KZN89173.1 - 0.00012 21.6 0.0 0.0027 17.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KZN89173.1 - 0.00016 21.4 0.3 0.00033 20.4 0.0 1.7 2 0 0 2 2 2 1 Starch synthase catalytic domain NMT1 PF09084.11 KZN89174.1 - 1.1e-77 260.8 0.0 1.4e-77 260.5 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 KZN89174.1 - 0.0049 16.6 0.4 0.21 11.2 0.0 3.0 3 1 1 4 4 4 1 NMT1-like family COG2 PF06148.11 KZN89176.1 - 9.1e-37 126.1 1.6 1.5e-36 125.4 1.6 1.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 KZN89176.1 - 1.5e-05 25.0 0.3 6.6e-05 22.9 0.2 2.2 1 1 1 2 2 2 1 Vps51/Vps67 COG5 PF10392.9 KZN89176.1 - 9.9e-05 22.5 0.5 0.00077 19.6 0.2 2.1 2 0 0 2 2 2 1 Golgi transport complex subunit 5 DUF4335 PF14233.6 KZN89176.1 - 0.00083 19.3 2.5 0.0081 16.1 2.5 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4335) Vps54_N PF10475.9 KZN89176.1 - 0.043 13.1 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Bul1_C PF04426.12 KZN89176.1 - 0.049 13.0 0.1 0.16 11.4 0.0 1.7 1 1 1 2 2 2 0 Bul1 C terminus Bcr-Abl_Oligo PF09036.10 KZN89176.1 - 0.2 11.7 1.1 0.71 9.9 0.0 2.4 3 0 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain TolA_bind_tri PF16331.5 KZN89176.1 - 0.35 11.0 8.2 0.5 10.5 0.2 3.6 4 0 0 4 4 4 0 TolA binding protein trimerisation Ribosomal_L1 PF00687.21 KZN89177.1 - 1e-28 100.5 0.0 1.2e-28 100.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family tRNA-synt_1c PF00749.21 KZN89178.1 - 1.4e-103 346.1 0.0 2e-103 345.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KZN89178.1 - 3.1e-37 128.1 0.2 5.4e-37 127.3 0.2 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C PF00043.25 KZN89178.1 - 0.026 14.7 0.0 0.065 13.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 KZN89178.1 - 0.039 13.3 0.2 0.11 11.8 0.1 1.6 1 1 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain GST_C_2 PF13410.6 KZN89178.1 - 0.14 12.2 0.1 0.4 10.7 0.1 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GluRS_N PF18466.1 KZN89178.1 - 0.21 12.0 0.0 0.21 12.0 0.0 2.5 3 0 0 3 3 3 0 Glutamate--tRNA ligase N-terminal domain E1-E2_ATPase PF00122.20 KZN89179.1 - 2e-35 122.0 5.3 9.7e-23 80.6 0.5 3.6 3 0 0 3 3 3 3 E1-E2 ATPase Hydrolase PF00702.26 KZN89179.1 - 4.1e-18 66.5 0.0 1.3e-17 64.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KZN89179.1 - 3.1e-09 36.4 0.0 6.2e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KZN89179.1 - 0.005 16.6 0.1 0.022 14.5 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Glyco_hydro_18 PF00704.28 KZN89180.1 - 2.9e-22 79.8 1.0 1.3e-21 77.7 0.9 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 SOG2 PF10428.9 KZN89180.1 - 0.037 13.2 19.6 0.046 12.9 19.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4551 PF15087.6 KZN89180.1 - 0.18 10.6 8.3 0.24 10.2 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Sec3_C PF09763.9 KZN89180.1 - 0.78 8.1 2.1 1.1 7.6 2.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Utp14 PF04615.13 KZN89180.1 - 2.1 6.8 11.5 3.2 6.2 11.5 1.2 1 0 0 1 1 1 0 Utp14 protein Macoilin PF09726.9 KZN89180.1 - 2.1 6.8 10.7 3.2 6.2 10.7 1.3 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 KZN89180.1 - 2.2 7.0 12.1 3.8 6.3 12.1 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 KZN89180.1 - 2.9 6.5 6.9 4.6 5.9 6.9 1.3 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 KZN89180.1 - 4.2 5.4 6.8 4.8 5.2 6.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ORC6 PF05460.13 KZN89180.1 - 4.2 6.6 17.5 5.8 6.1 17.5 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SPX PF03105.19 KZN89180.1 - 6.6 6.5 17.8 11 5.8 17.8 1.3 1 0 0 1 1 1 0 SPX domain MCRA PF06100.11 KZN89181.1 - 1.2e-171 571.9 0.0 1.3e-171 571.7 0.0 1.0 1 0 0 1 1 1 1 MCRA family DAO PF01266.24 KZN89181.1 - 7.1e-05 22.5 0.0 0.00021 21.0 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KZN89181.1 - 0.0046 17.2 0.1 0.011 16.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KZN89181.1 - 0.0055 15.8 0.5 0.058 12.5 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KZN89181.1 - 0.15 11.3 0.2 1.8 7.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NMT1 PF09084.11 KZN89182.1 - 0.00077 19.5 0.0 0.0031 17.5 0.0 1.9 1 1 1 2 2 2 1 NMT1/THI5 like NMT1_3 PF16868.5 KZN89182.1 - 0.0044 16.5 0.0 0.0068 15.9 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 KZN89182.1 - 0.026 14.1 0.0 0.045 13.3 0.0 1.5 1 1 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 KZN89182.1 - 0.061 12.7 0.0 1.2 8.5 0.0 2.3 3 0 0 3 3 3 0 Bacterial extracellular solute-binding proteins, family 3 Gag_p6 PF08705.11 KZN89182.1 - 0.44 10.8 3.2 0.84 9.9 3.2 1.5 1 0 0 1 1 1 0 Gag protein p6 PQ-loop PF04193.14 KZN89183.1 - 1.1e-20 73.2 3.5 4.8e-13 48.7 0.2 2.5 2 0 0 2 2 2 2 PQ loop repeat LMBR1 PF04791.16 KZN89183.1 - 0.00036 19.6 0.0 0.0012 17.8 0.0 1.6 1 1 1 2 2 2 1 LMBR1-like membrane protein ER_lumen_recept PF00810.18 KZN89183.1 - 0.097 13.5 4.6 0.24 12.2 2.7 2.2 1 1 1 2 2 2 0 ER lumen protein retaining receptor Phage_holin_5_2 PF16079.5 KZN89183.1 - 0.12 12.7 4.8 0.14 12.5 0.0 2.6 3 0 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V SurA_N_2 PF13623.6 KZN89184.1 - 0.17 11.8 0.5 0.43 10.5 0.5 1.7 1 0 0 1 1 1 0 SurA N-terminal domain Rootletin PF15035.6 KZN89184.1 - 5.6 6.9 15.7 31 4.5 15.7 2.1 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CENP-H PF05837.12 KZN89184.1 - 7.8 7.0 14.5 0.73 10.3 0.3 2.6 3 0 0 3 3 3 0 Centromere protein H (CENP-H) MFS_1 PF07690.16 KZN89185.1 - 1.2e-38 133.0 32.3 1.2e-38 133.0 32.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily SpoVAB PF13782.6 KZN89185.1 - 0.0019 18.5 2.4 0.0019 18.5 2.4 2.3 2 0 0 2 2 2 1 Stage V sporulation protein AB zf-H2C2_2 PF13465.6 KZN89185.1 - 9.3 6.9 7.7 42 4.8 2.3 2.5 2 0 0 2 2 2 0 Zinc-finger double domain Glyco_hydro_31 PF01055.26 KZN89186.1 - 2.9e-137 458.5 8.3 4.1e-137 458.0 8.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KZN89186.1 - 1.2e-25 89.6 0.5 7.4e-24 83.9 0.1 2.9 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KZN89186.1 - 4.8e-07 29.9 0.7 1.5e-06 28.4 0.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) NDK PF00334.19 KZN89187.1 - 3.6e-54 182.4 0.0 4.2e-54 182.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase FLILHELTA PF10306.9 KZN89188.1 - 1.6e-30 105.3 0.0 2.8e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 KZN89188.1 - 0.0012 19.4 0.0 0.0014 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Nop10p PF04135.12 KZN89188.1 - 0.17 12.0 2.2 0.32 11.0 2.2 1.4 1 0 0 1 1 1 0 Nucleolar RNA-binding protein, Nop10p family MTHFR PF02219.17 KZN89189.1 - 8.6e-96 320.6 0.0 1.2e-95 320.2 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase TGT PF01702.18 KZN89190.1 - 3.7e-66 223.7 0.0 4.7e-66 223.3 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Thymidylate_kin PF02223.17 KZN89191.1 - 3.1e-49 167.2 0.0 3.5e-49 167.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.10 KZN89191.1 - 0.0007 19.1 0.1 0.0031 17.0 0.0 1.9 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 KZN89191.1 - 0.056 13.8 0.0 0.076 13.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KZN89191.1 - 0.13 12.8 0.0 0.41 11.2 0.0 1.8 1 1 1 2 2 2 0 AAA domain GIY-YIG PF01541.24 KZN89192.1 - 4.6e-13 49.3 0.0 2.3e-12 47.0 0.0 2.2 3 0 0 3 3 3 1 GIY-YIG catalytic domain FANCL_C PF11793.8 KZN89192.1 - 5.9e-05 23.2 3.1 9.6e-05 22.5 3.1 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H PF13771.6 KZN89192.1 - 0.0073 16.5 0.9 0.015 15.5 0.9 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain Prok-RING_1 PF14446.6 KZN89192.1 - 0.01 15.8 2.4 0.01 15.8 2.4 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FYDLN_acid PF09538.10 KZN89192.1 - 0.13 12.9 0.3 0.13 12.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-RING_2 PF13639.6 KZN89192.1 - 2.1 8.7 8.8 0.81 10.1 6.0 1.8 2 0 0 2 2 2 0 Ring finger domain PLU-1 PF08429.11 KZN89193.1 - 1.7e-110 369.4 16.2 1.7e-106 356.2 14.7 2.3 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 KZN89193.1 - 4.1e-43 146.4 0.1 1.2e-42 145.0 0.1 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 KZN89193.1 - 2.2e-21 76.3 0.0 5.8e-21 75.0 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 KZN89193.1 - 1.8e-17 63.0 2.1 5.1e-17 61.5 2.1 1.9 1 0 0 1 1 1 1 jmjN domain PHD PF00628.29 KZN89193.1 - 3.5e-17 62.0 30.8 3.2e-09 36.5 8.2 3.6 3 0 0 3 3 3 2 PHD-finger zf-C5HC2 PF02928.16 KZN89193.1 - 1.9e-13 50.6 10.0 6.4e-13 48.9 10.0 2.0 1 0 0 1 1 1 1 C5HC2 zinc finger PHD_2 PF13831.6 KZN89193.1 - 0.0027 17.2 2.9 0.0027 17.2 2.9 2.8 3 0 0 3 3 3 1 PHD-finger zf-PHD-like PF15446.6 KZN89193.1 - 0.0081 15.8 1.8 0.0081 15.8 1.8 2.9 3 0 0 3 3 3 2 PHD/FYVE-zinc-finger like domain PALP PF00291.25 KZN89194.1 - 2.8e-35 122.2 0.0 3.4e-35 121.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DHHA2 PF02833.14 KZN89195.1 - 1.3e-30 106.5 0.1 6.3e-30 104.2 0.0 2.1 3 0 0 3 3 3 1 DHHA2 domain DHH PF01368.20 KZN89195.1 - 3.6e-07 30.4 0.0 6.7e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 DHH family Transglut_core PF01841.19 KZN89196.1 - 2.1e-08 34.6 0.0 4.5e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.17 KZN89196.1 - 7.9e-08 31.9 0.1 2.1e-07 30.5 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KZN89196.1 - 8.1e-06 25.3 0.5 1.9e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KZN89196.1 - 0.0045 16.8 0.3 0.02 14.7 0.2 2.1 2 0 0 2 2 2 1 Variant SH3 domain SAT PF16073.5 KZN89197.1 - 9.9e-87 290.6 0.2 6.2e-85 284.8 0.0 2.8 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ketoacyl-synt PF00109.26 KZN89197.1 - 1.3e-79 267.4 0.0 2.3e-79 266.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KZN89197.1 - 2.9e-43 148.6 0.1 8.3e-43 147.1 0.0 1.7 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KZN89197.1 - 1.4e-33 115.4 0.1 3.2e-33 114.2 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KZN89197.1 - 3.5e-23 81.7 5.4 3.5e-11 43.3 1.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.20 KZN89197.1 - 2.4e-21 76.9 0.0 1.5e-20 74.3 0.0 2.5 2 1 0 2 2 2 1 Thioesterase domain PS-DH PF14765.6 KZN89197.1 - 7.3e-13 48.4 0.0 1.2e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KZN89197.1 - 2.1e-05 24.9 0.2 8.7e-05 22.9 0.2 2.1 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KZN89197.1 - 0.00016 21.1 0.0 0.00039 19.9 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.7 KZN89197.1 - 0.00026 21.6 1.0 0.001 19.7 0.2 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family HDA2-3 PF11496.8 KZN89198.1 - 4.6e-49 167.2 0.0 6.7e-48 163.3 0.0 2.3 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 UBA2_C PF16195.5 KZN89198.1 - 0.042 14.5 0.2 0.042 14.5 0.2 3.9 5 0 0 5 5 5 0 SUMO-activating enzyme subunit 2 C-terminus Chromo PF00385.24 KZN89198.1 - 0.14 12.1 1.3 0.35 10.8 1.3 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain TMEM192 PF14802.6 KZN89198.1 - 0.23 10.5 2.4 0.53 9.3 2.4 1.6 1 0 0 1 1 1 0 TMEM192 family IFT57 PF10498.9 KZN89198.1 - 0.35 9.8 16.3 0.046 12.7 10.7 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 GAS PF13851.6 KZN89198.1 - 0.72 9.2 30.7 2.8 7.3 16.7 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 KZN89198.1 - 1.5 8.8 43.0 5.4 7.0 3.9 4.2 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RasGAP_C PF03836.15 KZN89198.1 - 3.9 7.6 13.1 1.3 9.2 2.5 2.8 2 0 0 2 2 2 0 RasGAP C-terminus FMO-like PF00743.19 KZN89199.1 - 2e-43 148.6 0.0 1.3e-25 89.8 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KZN89199.1 - 9.2e-15 54.7 0.0 5e-12 45.7 0.0 2.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KZN89199.1 - 3.6e-12 46.1 0.2 3.5e-09 36.3 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KZN89199.1 - 5.1e-12 45.6 0.0 1.4e-11 44.2 0.0 1.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KZN89199.1 - 1.7e-11 44.3 0.0 1.1e-10 41.7 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KZN89199.1 - 1.9e-06 28.0 0.2 1.7e-05 24.9 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KZN89199.1 - 5.1e-06 25.9 0.1 0.00055 19.3 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KZN89199.1 - 3.8e-05 23.4 0.0 0.55 9.8 0.0 3.3 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KZN89199.1 - 0.0021 18.6 0.2 4.7 7.8 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KZN89199.1 - 0.0034 16.1 0.1 0.37 9.4 0.0 2.7 3 0 0 3 3 3 1 HI0933-like protein GyrB_insert PF18053.1 KZN89199.1 - 0.13 12.1 0.3 1.9 8.3 0.0 2.1 2 0 0 2 2 2 0 DNA gyrase B subunit insert domain Semialdhyde_dh PF01118.24 KZN89199.1 - 0.16 12.4 0.0 1.9 8.9 0.0 2.5 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain POT1 PF02765.17 KZN89200.1 - 1e-15 57.9 0.0 1.7e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 FancD2 PF14631.6 KZN89200.1 - 9.1 3.5 5.5 14 2.9 5.5 1.2 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease NUDIX-like PF09296.11 KZN89201.1 - 8.3e-21 74.6 0.0 2.5e-20 73.0 0.0 1.8 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain NUDIX PF00293.28 KZN89201.1 - 6.3e-18 65.1 0.1 1.3e-17 64.1 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 KZN89201.1 - 1.1e-05 24.9 1.7 2.5e-05 23.8 1.7 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DpnI PF06044.12 KZN89201.1 - 0.12 12.0 0.1 2.2 7.9 0.0 2.5 3 0 0 3 3 3 0 Dam-replacing family CN_hydrolase PF00795.22 KZN89202.1 - 6.1e-44 150.3 0.0 8.1e-44 149.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KZN89202.1 - 6.8e-18 64.7 0.0 1.2e-07 31.1 0.0 3.0 2 2 0 2 2 2 2 NAD synthase Questin_oxidase PF14027.6 KZN89204.1 - 2.1e-100 336.6 0.0 2.8e-100 336.2 0.0 1.2 1 0 0 1 1 1 1 Questin oxidase-like ERCC3_RAD25_C PF16203.5 KZN89205.1 - 3.4e-124 412.9 1.9 6.1e-124 412.1 1.9 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KZN89205.1 - 5.5e-36 123.5 0.0 1.5e-35 122.1 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KZN89205.1 - 5.1e-16 59.1 0.0 9.6e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KZN89205.1 - 1.8e-13 50.8 0.1 4.2e-13 49.6 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KZN89205.1 - 1.1e-09 37.5 0.0 1.4e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 KZN89205.1 - 0.00066 19.5 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 KZN89205.1 - 0.0014 17.6 0.0 0.0024 16.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DUF4748 PF15932.5 KZN89206.1 - 9.3e-20 70.1 0.7 1.7e-19 69.3 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) PIEZO PF15917.5 KZN89206.1 - 0.0064 16.0 0.2 0.0076 15.8 0.2 1.0 1 0 0 1 1 1 1 Piezo T2SSM PF04612.12 KZN89206.1 - 0.044 13.8 0.1 0.063 13.3 0.1 1.3 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein M CTD_bind PF04818.13 KZN89208.1 - 1.4e-09 38.6 0.0 2.8e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF515 PF04415.12 KZN89208.1 - 6.9 4.9 5.4 10 4.3 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SR-25 PF10500.9 KZN89208.1 - 8.7 5.9 24.6 12 5.4 24.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCDC24 PF15669.5 KZN89210.1 - 0.09 12.6 3.1 0.11 12.3 3.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family EMP24_GP25L PF01105.24 KZN89211.1 - 1.7e-47 161.7 4.1 1.9e-47 161.5 4.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD GHD PF17834.1 KZN89211.1 - 0.24 11.5 0.3 0.24 11.5 0.3 1.9 2 0 0 2 2 2 0 Beta-sandwich domain in beta galactosidase USP7_ICP0_bdg PF12436.8 KZN89212.1 - 3e-85 285.4 1.6 7.5e-85 284.1 0.7 2.1 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KZN89212.1 - 1.1e-72 244.0 3.2 5.8e-70 235.2 0.0 3.2 3 1 0 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 KZN89212.1 - 2.6e-49 168.0 0.7 2.6e-49 168.0 0.7 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KZN89212.1 - 5.6e-21 75.5 0.0 1.3e-20 74.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KZN89212.1 - 1.9e-06 28.0 0.0 6.1e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 MATH domain Rad60-SLD PF11976.8 KZN89212.1 - 0.0024 17.7 2.5 1.3 8.9 0.1 4.6 4 1 0 4 4 4 1 Ubiquitin-2 like Rad60 SUMO-like PreAtp-grasp PF18604.1 KZN89212.1 - 0.11 12.2 0.1 1.2 8.8 0.0 2.8 4 0 0 4 4 4 0 Pre ATP-grasp domain BCDHK_Adom3 PF10436.9 KZN89213.1 - 1.8e-43 148.2 0.1 1.1e-42 145.7 0.0 2.1 3 0 0 3 3 3 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KZN89213.1 - 3.9e-06 27.4 0.0 1.5e-05 25.4 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KZN89213.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pmp3 PF01679.17 KZN89214.1 - 1.8e-21 76.0 9.4 2.3e-21 75.7 9.4 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF3165 PF11364.8 KZN89214.1 - 0.094 13.1 0.8 0.13 12.6 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3165) NapE PF06796.11 KZN89214.1 - 1.5 8.4 4.3 1.9 8.1 4.3 1.2 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE SPC22 PF04573.12 KZN89215.1 - 3.6e-39 134.0 0.3 3.3e-28 98.3 0.2 2.2 2 0 0 2 2 2 2 Signal peptidase subunit GGACT PF06094.12 KZN89216.1 - 2.7e-17 63.5 0.0 7.6e-17 62.0 0.0 1.6 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Peptidase_C48 PF02902.19 KZN89217.1 - 9.3e-33 113.9 0.0 7.7e-32 110.9 0.0 2.4 2 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Med21 PF11221.8 KZN89217.1 - 9.9 6.4 10.6 5.2 7.3 0.1 3.9 3 0 0 3 3 3 0 Subunit 21 of Mediator complex IF4E PF01652.18 KZN89218.1 - 8.2e-55 184.9 0.0 1.3e-54 184.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Pkinase PF00069.25 KZN89219.1 - 4.8e-69 232.7 0.0 6.2e-69 232.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN89219.1 - 2e-34 119.0 0.0 3.6e-34 118.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KZN89219.1 - 0.0043 16.4 0.0 0.0073 15.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KZN89219.1 - 0.036 12.8 0.0 0.091 11.5 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KZN89219.1 - 0.091 12.1 0.2 0.2 11.0 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family OB_MalK PF17912.1 KZN89220.1 - 0.11 13.4 0.1 0.43 11.5 0.1 2.0 2 0 0 2 2 2 0 MalK OB fold domain GTP_cyclohydroI PF01227.22 KZN89221.1 - 7.6e-73 243.7 0.5 1e-72 243.3 0.5 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KZN89221.1 - 0.012 15.7 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 QueF-like protein CAF1C_H4-bd PF12265.8 KZN89222.1 - 4.6e-29 100.5 0.7 2.4e-28 98.2 0.8 2.2 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KZN89222.1 - 4.1e-26 90.7 13.0 3.4e-06 27.7 0.2 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN89222.1 - 7.9e-06 26.1 0.6 0.2 12.0 0.0 4.4 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KZN89222.1 - 0.0044 15.7 0.6 2 6.9 0.3 3.6 2 1 0 3 3 3 2 Nucleoporin Nup120/160 DUF3751 PF12571.8 KZN89222.1 - 0.021 14.9 0.0 2 8.5 0.0 2.3 2 0 0 2 2 2 0 Phage tail-collar fibre protein XRN_M PF17846.1 KZN89223.1 - 1.9e-101 340.2 5.6 3e-101 339.6 5.6 1.2 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 KZN89223.1 - 1.2e-96 322.8 0.0 2.5e-96 321.8 0.0 1.6 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 KZN89223.1 - 1.8e-73 246.4 0.0 4.6e-73 245.1 0.0 1.7 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 KZN89223.1 - 2.3e-32 111.0 0.0 6.8e-32 109.5 0.0 1.9 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 KZN89223.1 - 9.7e-24 83.3 0.3 2.1e-23 82.2 0.3 1.6 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 KZN89223.1 - 7.5e-08 32.4 0.1 2.4e-07 30.7 0.1 1.9 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 DUF1345 PF07077.11 KZN89223.1 - 0.16 11.6 0.1 0.3 10.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) p450 PF00067.22 KZN89224.1 - 1.7e-30 106.2 0.3 4.8e-30 104.7 0.3 1.6 1 1 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 KZN89225.1 - 2.4e-41 138.9 21.4 1.9e-09 38.0 0.5 12.4 13 0 0 13 13 13 7 WD domain, G-beta repeat Utp12 PF04003.12 KZN89225.1 - 3.4e-28 98.1 0.0 5.5e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KZN89225.1 - 3.6e-26 91.3 0.0 0.00044 20.5 0.0 10.8 6 2 6 13 13 13 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KZN89225.1 - 1.7e-09 37.1 1.0 0.077 11.9 0.0 4.8 3 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KZN89225.1 - 4.7e-08 33.1 3.0 0.022 14.6 0.1 6.5 6 2 1 7 7 7 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KZN89225.1 - 1.7e-05 23.7 5.5 2.6 6.6 0.0 5.3 1 1 2 5 5 5 4 Nucleoporin Nup120/160 WD40_like PF17005.5 KZN89225.1 - 0.00059 19.2 0.0 0.19 11.0 0.0 3.7 4 1 1 5 5 5 2 WD40-like domain Nbas_N PF15492.6 KZN89225.1 - 0.0036 16.7 0.4 3.9 6.7 0.0 3.6 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PQQ_3 PF13570.6 KZN89225.1 - 0.0068 16.9 4.0 5 7.7 0.1 5.8 7 0 0 7 7 6 1 PQQ-like domain PD40 PF07676.12 KZN89225.1 - 0.02 14.8 0.2 12 5.9 0.0 4.5 6 0 0 6 6 5 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 KZN89225.1 - 0.026 13.6 0.0 2.6 7.0 0.0 3.2 3 1 1 4 4 4 0 Coatomer WD associated region DUF1513 PF07433.11 KZN89225.1 - 0.038 13.1 0.7 2.7 7.0 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) RAB3GAP2_N PF14655.6 KZN89225.1 - 0.093 12.0 0.1 2.8 7.1 0.0 3.1 3 1 0 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Septin PF00735.18 KZN89226.1 - 2.7e-110 368.1 0.6 4.1e-110 367.5 0.6 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KZN89226.1 - 9.5e-07 28.9 0.0 2e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KZN89226.1 - 9.5e-06 25.3 2.8 0.00018 21.1 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KZN89226.1 - 2.9e-05 24.0 0.4 0.00043 20.2 0.0 2.6 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 KZN89226.1 - 0.0022 18.3 0.5 0.007 16.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain FOXP-CC PF16159.5 KZN89226.1 - 0.0073 16.9 1.0 0.028 15.0 1.0 2.0 1 0 0 1 1 1 1 FOXP coiled-coil domain Roc PF08477.13 KZN89226.1 - 0.023 14.9 0.1 0.052 13.8 0.1 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KZN89226.1 - 0.095 12.3 0.8 0.3 10.7 0.5 2.0 2 1 0 2 2 2 0 Ras family Pox_A32 PF04665.12 KZN89226.1 - 0.1 12.1 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein ABC_tran PF00005.27 KZN89226.1 - 0.13 12.7 0.1 0.59 10.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter ATP_bind_1 PF03029.17 KZN89226.1 - 0.15 11.8 1.0 12 5.6 0.1 2.8 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 KZN89226.1 - 2.1 8.4 6.2 5.3 7.1 0.1 3.0 2 1 1 3 3 3 0 Dynamin family Myc-LZ PF02344.15 KZN89226.1 - 2.4 8.3 4.8 4.3 7.5 0.4 2.6 2 0 0 2 2 2 0 Myc leucine zipper domain Casc1_N PF15927.5 KZN89226.1 - 5.9 6.5 14.0 0.21 11.2 7.5 1.8 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus WD40 PF00400.32 KZN89227.1 - 6e-23 80.7 13.3 8.3e-06 26.4 0.6 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN89227.1 - 2.3e-10 40.6 0.6 0.05 13.9 0.0 5.1 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain VID27 PF08553.10 KZN89227.1 - 0.00024 20.3 0.0 0.00036 19.7 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain eIF2A PF08662.11 KZN89227.1 - 0.0032 17.4 0.2 0.019 14.9 0.0 2.3 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PQQ PF01011.21 KZN89227.1 - 0.019 14.9 0.2 0.31 11.1 0.0 2.7 2 0 0 2 2 2 0 PQQ enzyme repeat BBS2_Mid PF14783.6 KZN89227.1 - 0.052 13.6 0.0 0.92 9.6 0.0 2.8 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region FLgD_tudor PF13861.6 KZN89227.1 - 0.17 12.1 3.0 11 6.3 0.1 3.5 3 0 0 3 3 3 0 FlgD Tudor-like domain GPS PF01825.21 KZN89227.1 - 9.8 6.8 6.1 4.7 7.8 1.2 2.5 2 0 0 2 2 2 0 GPCR proteolysis site, GPS, motif ACT_7 PF13840.6 KZN89228.1 - 6.7e-26 89.9 0.1 3.2e-17 62.0 0.0 3.5 3 0 0 3 3 3 3 ACT domain Cu-oxidase_3 PF07732.15 KZN89229.1 - 1.3e-39 134.9 0.5 1.3e-39 134.9 0.5 3.3 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KZN89229.1 - 3.6e-39 133.6 14.5 1.8e-37 128.1 5.0 3.4 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KZN89229.1 - 1.4e-35 122.7 1.3 3.3e-34 118.3 0.1 3.0 3 0 0 3 3 3 1 Multicopper oxidase SH3-WW_linker PF16618.5 KZN89230.1 - 0.098 13.1 10.4 0.24 11.8 10.4 1.6 1 0 0 1 1 1 0 Linker region between SH3 and WW domains on ARHGAP12 Nop14 PF04147.12 KZN89230.1 - 0.11 10.7 3.3 0.11 10.7 3.3 1.1 1 0 0 1 1 1 0 Nop14-like family SRP9-21 PF05486.12 KZN89230.1 - 0.29 11.5 1.1 0.58 10.6 0.0 2.2 2 2 0 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) TRP PF06011.12 KZN89232.1 - 1.6e-05 23.8 19.4 0.064 12.0 7.1 2.9 1 1 1 2 2 2 2 Transient receptor potential (TRP) ion channel DUF5480 PF17576.2 KZN89232.1 - 1.3 9.1 5.8 22 5.1 0.2 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5480) SIT PF15330.6 KZN89232.1 - 1.5 9.3 0.0 1.5 9.3 0.0 3.7 4 0 0 4 4 4 0 SHP2-interacting transmembrane adaptor protein, SIT Scytalone_dh PF02982.14 KZN89233.1 - 1.6e-77 258.7 3.1 2e-77 258.4 3.1 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 KZN89233.1 - 3.9e-08 33.5 1.8 4.7e-08 33.2 1.8 1.1 1 0 0 1 1 1 1 SnoaL-like domain adh_short_C2 PF13561.6 KZN89234.1 - 2.2e-56 191.1 0.2 3.8e-56 190.3 0.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN89234.1 - 6.3e-49 166.1 1.0 8.2e-49 165.7 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN89234.1 - 3.1e-17 63.1 1.0 4e-17 62.7 1.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KZN89234.1 - 0.0038 16.7 0.4 0.0058 16.1 0.4 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KZN89234.1 - 0.0039 16.5 0.1 0.12 11.6 0.1 2.2 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 KZN89234.1 - 0.018 14.5 0.1 0.028 13.8 0.1 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF2855 PF11017.8 KZN89234.1 - 0.14 11.8 0.9 11 5.7 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2855) NmrA PF05368.13 KZN89234.1 - 0.18 11.4 1.7 0.54 9.8 1.7 1.8 3 0 0 3 3 3 0 NmrA-like family DUF1100 PF06500.11 KZN89235.1 - 2.3e-10 39.8 0.0 3e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S15 PF02129.18 KZN89235.1 - 2.5e-06 27.3 0.0 3.5e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 KZN89235.1 - 0.0002 20.9 0.0 0.00049 19.6 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 KZN89235.1 - 0.0022 18.0 0.0 0.0034 17.3 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 KZN89235.1 - 0.012 16.2 1.3 0.016 15.8 0.8 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.20 KZN89235.1 - 0.037 13.7 0.0 0.24 11.0 0.0 2.0 1 1 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.8 KZN89235.1 - 0.085 12.1 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MIT PF04212.18 KZN89235.1 - 0.097 12.8 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain SKIP_SNW PF02731.15 KZN89236.1 - 4.4e-72 241.0 3.6 4.4e-72 241.0 3.6 2.4 2 0 0 2 2 2 1 SKIP/SNW domain Nucleo_P87 PF07267.11 KZN89236.1 - 3.1 6.6 8.1 5.7 5.7 8.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF3395 PF11875.8 KZN89237.1 - 1.6e-44 151.5 0.0 3.7e-44 150.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 KZN89237.1 - 5.9e-18 64.8 0.2 1.4e-17 63.5 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain NAAA-beta PF15508.6 KZN89238.1 - 3.8e-16 59.1 0.2 6.8e-16 58.3 0.2 1.4 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Zwint PF15556.6 KZN89238.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 ZW10 interactor Fungal_trans PF04082.18 KZN89239.1 - 3e-14 52.7 1.1 5.6e-14 51.8 1.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN89239.1 - 2e-05 24.6 9.8 3.5e-05 23.8 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L4 PF00573.22 KZN89240.1 - 9.9e-39 133.0 0.3 1.4e-38 132.5 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KZN89240.1 - 7e-30 102.9 0.8 7e-30 102.9 0.8 1.8 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Diphtheria_T PF02764.14 KZN89240.1 - 0.055 13.5 0.1 0.096 12.7 0.1 1.3 1 0 0 1 1 1 0 Diphtheria toxin, T domain Glyco_hydro_61 PF03443.14 KZN89241.1 - 0.001 19.1 0.1 0.0036 17.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 DEC-1_N PF04625.13 KZN89241.1 - 1.1 8.1 3.7 1.8 7.5 3.7 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region UPF0029 PF01205.19 KZN89242.1 - 2.5e-35 121.0 0.1 3.9e-35 120.4 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KZN89242.1 - 1.4e-06 28.5 0.0 2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 RWD domain DUF2340 PF10209.9 KZN89243.1 - 0.07 13.6 0.0 0.079 13.4 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) LCCL PF03815.19 KZN89244.1 - 3.2e-23 81.6 0.1 5e-23 81.0 0.1 1.3 1 0 0 1 1 1 1 LCCL domain Fungal_trans PF04082.18 KZN89245.1 - 7.8e-07 28.4 1.2 8.9e-06 24.9 0.3 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN89245.1 - 9.5e-05 22.4 4.4 0.00017 21.7 4.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Vps51 PF08700.11 KZN89245.1 - 0.06 13.4 0.2 3.1 7.9 0.0 2.7 2 0 0 2 2 2 0 Vps51/Vps67 tRNA_bind_3 PF17176.4 KZN89245.1 - 0.088 13.1 0.1 1.2 9.5 0.0 2.5 2 0 0 2 2 2 0 tRNA-binding domain BLOC1_2 PF10046.9 KZN89245.1 - 0.23 11.8 1.0 0.74 10.2 0.2 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Asparaginase PF00710.20 KZN89246.1 - 9e-59 198.2 0.0 1.3e-58 197.7 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KZN89246.1 - 8.6e-28 96.9 0.1 2.5e-27 95.4 0.1 1.8 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 KZN89246.1 - 3.7e-09 37.0 0.0 4.2e-08 33.7 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN89246.1 - 9.2e-09 35.7 0.5 0.00025 21.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KZN89246.1 - 8.5e-07 29.2 1.1 0.00058 20.2 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KZN89246.1 - 8.9e-07 28.8 0.5 0.0026 18.1 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KZN89246.1 - 1.6e-05 25.1 0.1 4e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) MTTB PF06253.11 KZN89246.1 - 0.058 11.4 0.3 0.086 10.8 0.3 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) NmrA PF05368.13 KZN89247.1 - 1e-69 234.7 0.0 1.2e-69 234.4 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAP PF00956.18 KZN89248.1 - 5e-32 111.2 8.7 1.8e-28 99.5 3.7 2.2 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Syntaxin-6_N PF09177.11 KZN89249.1 - 3.7e-25 88.3 1.1 1.3e-24 86.6 0.2 2.1 2 0 0 2 2 2 1 Syntaxin 6, N-terminal DUF4795 PF16043.5 KZN89249.1 - 4.3e-05 23.2 3.3 0.00027 20.6 3.8 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) SNARE PF05739.19 KZN89249.1 - 0.0012 18.8 4.8 0.0017 18.3 0.6 2.4 2 0 0 2 2 2 1 SNARE domain Prominin PF05478.11 KZN89249.1 - 0.0014 16.8 0.2 0.0019 16.3 0.2 1.2 1 0 0 1 1 1 1 Prominin ApoLp-III PF07464.11 KZN89249.1 - 0.068 13.3 2.7 0.51 10.4 0.9 2.6 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) LXG PF04740.12 KZN89249.1 - 0.089 12.5 3.4 0.37 10.5 0.4 2.2 2 0 0 2 2 2 0 LXG domain of WXG superfamily Baculo_PEP_C PF04513.12 KZN89249.1 - 0.14 12.2 1.5 3.9 7.5 0.7 2.9 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus STAT_alpha PF01017.20 KZN89249.1 - 0.18 11.7 3.9 0.74 9.7 3.9 2.0 1 1 0 1 1 1 0 STAT protein, all-alpha domain DUF2072 PF09845.9 KZN89249.1 - 0.24 11.6 1.6 0.38 11.0 0.3 1.8 1 1 1 2 2 2 0 Zn-ribbon containing protein DUF1664 PF07889.12 KZN89249.1 - 0.87 9.6 6.1 8.5 6.4 0.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 KZN89249.1 - 1.3 9.6 7.7 18 5.8 0.1 3.5 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein ATG16 PF08614.11 KZN89249.1 - 2.1 8.6 11.5 4.6 7.4 4.3 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Pkinase PF00069.25 KZN89250.1 - 1e-62 211.9 0.0 1.5e-62 211.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN89250.1 - 7.1e-39 133.6 0.0 1.1e-38 133.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KZN89250.1 - 3.1e-06 26.7 0.0 1.2e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KZN89250.1 - 0.00084 18.8 0.1 0.0015 17.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KZN89251.1 - 2.9e-14 53.6 0.0 3.3e-13 50.1 0.0 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KZN89251.1 - 0.024 13.5 0.0 0.76 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EcKinase PF02958.20 KZN89251.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Rad60-SLD PF11976.8 KZN89251.1 - 0.12 12.2 0.1 0.28 11.0 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Methyltransf_32 PF13679.6 KZN89252.1 - 1.5e-23 83.6 0.4 7.3e-23 81.3 0.4 1.9 1 1 0 1 1 1 1 Methyltransferase domain RNA_pol_L_2 PF13656.6 KZN89252.1 - 0.023 14.5 0.1 0.057 13.2 0.1 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Cupin_2 PF07883.11 KZN89254.1 - 7.4e-08 32.0 0.2 0.00071 19.2 0.0 2.5 2 1 0 2 2 2 2 Cupin domain Cupin_1 PF00190.22 KZN89254.1 - 6e-06 25.9 0.0 9.4e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Cupin MIX PF18529.1 KZN89254.1 - 0.05 13.3 0.0 0.078 12.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial membrane-anchored proteins PH_11 PF15413.6 KZN89254.1 - 0.093 13.2 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain Abhydrolase_2 PF02230.16 KZN89258.1 - 1.3e-14 54.5 0.0 1.7e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KZN89258.1 - 0.00085 20.0 0.4 0.0011 19.6 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3759 PF12585.8 KZN89259.1 - 5e-39 132.2 11.3 5.8e-39 132.0 11.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) SPX PF03105.19 KZN89260.1 - 6.6e-88 296.2 6.3 8.3e-88 295.9 6.3 1.1 1 0 0 1 1 1 1 SPX domain EXS PF03124.14 KZN89260.1 - 1.2e-09 38.0 0.5 1.8e-09 37.4 0.5 1.3 1 0 0 1 1 1 1 EXS family Aa_trans PF01490.18 KZN89261.1 - 9.3e-40 136.6 39.1 1.1e-39 136.3 39.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Bax1-I PF01027.20 KZN89262.1 - 6.5e-51 173.1 29.3 7.4e-51 172.9 29.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Spore_YhaL PF14147.6 KZN89262.1 - 0.2 11.3 1.2 0.52 10.0 0.3 2.2 2 0 0 2 2 2 0 Sporulation protein YhaL DUF1011 PF06237.12 KZN89262.1 - 1.3 9.4 10.5 10 6.5 1.1 3.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1011) Aa_trans PF01490.18 KZN89263.1 - 3.4e-91 306.0 13.8 5e-91 305.4 13.8 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KZN89263.1 - 9.4e-06 24.9 15.4 9.4e-06 24.9 15.4 1.7 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family adh_short PF00106.25 KZN89264.1 - 7e-36 123.5 0.0 9.3e-36 123.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN89264.1 - 2.2e-29 102.7 0.0 3.4e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN89264.1 - 0.00017 21.5 0.0 0.014 15.3 0.0 2.2 2 0 0 2 2 2 1 KR domain DcuA_DcuB PF03605.14 KZN89264.1 - 0.036 13.0 0.1 0.047 12.6 0.1 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter DNA_ligase_A_C PF04679.15 KZN89264.1 - 0.081 13.5 0.0 0.47 11.1 0.0 2.1 2 0 0 2 2 2 0 ATP dependent DNA ligase C terminal region DUF1479 PF07350.12 KZN89265.1 - 1.4e-167 557.7 0.0 1.6e-167 557.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) EMC1_C PF07774.13 KZN89267.1 - 2.1e-77 259.6 0.0 1e-76 257.3 0.0 2.0 2 0 0 2 2 2 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KZN89267.1 - 5e-27 95.0 16.5 1.9e-25 89.8 4.9 2.8 2 1 1 3 3 3 2 PQQ-like domain PQQ PF01011.21 KZN89267.1 - 1.7e-07 30.8 0.1 0.25 11.3 0.0 4.9 4 0 0 4 4 4 2 PQQ enzyme repeat PQQ_3 PF13570.6 KZN89267.1 - 1.3 9.7 0.0 1.3 9.7 0.0 5.3 6 0 0 6 6 6 0 PQQ-like domain FA_hydroxylase PF04116.13 KZN89268.1 - 3.3e-22 79.3 11.9 3.3e-22 79.3 11.9 2.7 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily CRAL_TRIO PF00650.20 KZN89269.1 - 1.8e-24 86.3 0.0 2.4e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KZN89269.1 - 3.1e-10 40.1 0.5 1.1e-09 38.3 0.5 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain SNase PF00565.17 KZN89270.1 - 2.7e-73 243.3 0.0 1.5e-23 83.3 0.0 5.5 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 KZN89270.1 - 2.5e-22 79.2 0.0 1e-21 77.2 0.0 2.1 2 0 0 2 2 2 1 Tudor domain SMN PF06003.12 KZN89270.1 - 0.00022 20.6 0.0 0.00041 19.7 0.0 1.3 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Agenet PF05641.12 KZN89270.1 - 0.025 15.0 0.0 0.15 12.6 0.0 2.3 2 0 0 2 2 2 0 Agenet domain Sod_Cu PF00080.20 KZN89271.1 - 4.9e-45 153.2 4.2 6.6e-45 152.8 4.2 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) TAL_FSA PF00923.19 KZN89272.1 - 1.1e-90 303.9 0.2 1.3e-90 303.6 0.2 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Beach PF02138.18 KZN89273.1 - 4.4e-118 393.7 0.0 7.7e-118 392.8 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 KZN89273.1 - 6.2e-13 48.7 0.1 1.4e-12 47.6 0.1 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 KZN89273.1 - 6e-09 36.2 0.0 1.7e-08 34.8 0.0 1.7 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 KZN89273.1 - 2.7e-07 31.2 3.0 0.0011 19.7 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat Peptidase_S8 PF00082.22 KZN89274.1 - 4.1e-39 134.6 11.2 6.4e-39 134.0 11.2 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KZN89274.1 - 4.6e-21 75.3 0.1 8.6e-21 74.4 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Cu-oxidase PF00394.22 KZN89275.1 - 3.2e-30 105.3 0.0 1e-29 103.7 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KZN89275.1 - 5e-27 94.3 0.2 1.2e-25 89.8 0.0 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KZN89275.1 - 5.6e-25 87.7 8.0 3.3e-21 75.5 4.0 3.5 2 2 0 2 2 2 2 Multicopper oxidase UQ_con PF00179.26 KZN89276.1 - 2.5e-38 130.9 0.0 3.1e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KZN89276.1 - 0.089 12.5 0.0 0.3 10.8 0.0 1.8 1 1 0 1 1 1 0 Prokaryotic E2 family B TPR_12 PF13424.6 KZN89280.1 - 1.3e-10 41.4 5.2 8.4e-06 26.0 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat AAA_16 PF13191.6 KZN89280.1 - 7.1e-10 39.5 1.4 9.9e-09 35.8 0.0 3.6 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 KZN89280.1 - 2.8e-05 24.1 0.3 0.00024 21.1 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KZN89280.1 - 3.2e-05 24.2 0.2 0.00028 21.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain TPR_10 PF13374.6 KZN89280.1 - 0.0003 20.6 0.9 0.021 14.7 0.0 4.6 6 0 0 6 6 6 1 Tetratricopeptide repeat ATPase_2 PF01637.18 KZN89280.1 - 0.0093 15.9 0.3 0.08 12.8 0.0 2.8 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea TsaE PF02367.17 KZN89280.1 - 0.049 13.6 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rossmann-like PF10727.9 KZN89280.1 - 0.21 11.4 0.6 25 4.8 0.1 3.0 3 0 0 3 3 3 0 Rossmann-like domain ABC_tran PF00005.27 KZN89280.1 - 0.78 10.3 3.9 1.4 9.4 0.0 3.4 3 0 0 3 3 3 0 ABC transporter ABC_tran PF00005.27 KZN89282.1 - 7.1e-55 185.3 0.1 1.2e-31 110.0 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KZN89282.1 - 1.2e-50 172.8 21.7 6.9e-33 114.5 3.5 3.4 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KZN89282.1 - 1.3e-07 31.3 5.0 0.015 14.8 0.3 3.9 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KZN89282.1 - 3.1e-07 31.1 0.6 0.00033 21.2 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KZN89282.1 - 3.7e-07 30.3 0.2 0.0054 16.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KZN89282.1 - 5.9e-05 23.1 0.8 0.074 13.1 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KZN89282.1 - 6.3e-05 23.3 1.9 3.7 7.8 0.0 3.5 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KZN89282.1 - 7.3e-05 22.7 1.3 0.079 12.9 0.1 2.8 3 0 0 3 3 2 2 RsgA GTPase DUF87 PF01935.17 KZN89282.1 - 7.4e-05 22.9 1.5 0.045 13.9 0.2 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_16 PF13191.6 KZN89282.1 - 0.00073 20.0 1.2 1.7 9.0 0.0 3.2 3 1 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 KZN89282.1 - 0.001 18.7 2.4 0.64 9.8 0.1 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain T2SSE PF00437.20 KZN89282.1 - 0.0019 17.3 0.1 0.038 13.1 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 KZN89282.1 - 0.002 17.9 0.0 1.1 8.9 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.6 KZN89282.1 - 0.0027 17.3 0.3 0.93 9.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 KZN89282.1 - 0.0044 16.6 0.2 2.3 7.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 KZN89282.1 - 0.011 15.0 0.9 4.3 6.6 0.1 2.8 3 0 0 3 3 3 0 Zeta toxin AAA_30 PF13604.6 KZN89282.1 - 0.024 14.4 0.7 3.9 7.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 KZN89282.1 - 0.033 14.6 0.7 3.7 8.0 0.1 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KZN89282.1 - 0.062 12.9 4.2 0.51 9.9 0.3 3.0 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 KZN89282.1 - 0.081 12.6 2.7 0.24 11.1 0.1 2.6 3 0 0 3 3 3 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 KZN89282.1 - 0.12 11.2 2.7 2.8 6.7 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Adeno_IVa2 PF02456.15 KZN89282.1 - 0.14 10.9 0.0 0.36 9.6 0.0 1.6 2 0 0 2 2 2 0 Adenovirus IVa2 protein PhoH PF02562.16 KZN89282.1 - 0.19 11.1 0.9 13 5.2 0.0 2.8 3 0 0 3 3 3 0 PhoH-like protein TIP49 PF06068.13 KZN89282.1 - 0.2 10.8 1.0 9.9 5.2 0.2 2.2 2 0 0 2 2 2 0 TIP49 P-loop domain NACHT PF05729.12 KZN89282.1 - 0.25 11.2 2.6 2.9 7.8 0.2 2.7 2 0 0 2 2 2 0 NACHT domain Roc PF08477.13 KZN89282.1 - 0.25 11.5 3.6 13 6.0 0.1 2.8 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KZN89282.1 - 0.26 11.3 3.0 4.2 7.4 0.1 2.8 3 0 0 3 3 2 0 Dynamin family AAA_24 PF13479.6 KZN89282.1 - 0.26 11.0 0.8 12 5.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KZN89282.1 - 0.3 11.6 1.9 17 5.9 0.2 3.0 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KZN89282.1 - 0.64 9.3 3.4 2.3 7.5 0.1 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family S_4TM PF18159.1 KZN89282.1 - 6.9 5.9 14.4 4.7 6.4 0.0 4.7 5 0 0 5 5 5 0 SMODS-associating 4TM effector domain Polysacc_deac_1 PF01522.21 KZN89284.1 - 2.1e-18 66.4 0.0 4.1e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KZN89284.1 - 6.8e-06 25.9 0.0 1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Amidase PF01425.21 KZN89285.1 - 2.6e-90 303.5 0.1 3.3e-90 303.2 0.1 1.1 1 0 0 1 1 1 1 Amidase Fungal_trans PF04082.18 KZN89286.1 - 3.3e-19 68.9 0.1 6.4e-19 68.0 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KZN89286.1 - 1.4e-06 28.4 15.0 0.00034 20.9 4.0 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KZN89286.1 - 0.0027 18.4 13.4 0.0056 17.4 2.4 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KZN89286.1 - 0.0039 17.6 1.4 0.0039 17.6 1.4 3.2 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KZN89286.1 - 0.16 12.3 0.2 0.34 11.3 0.2 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-UBR PF02207.20 KZN89286.1 - 0.17 12.1 0.6 0.32 11.2 0.6 1.3 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) AAA_12 PF13087.6 KZN89287.1 - 5.5e-42 143.7 0.0 9.5e-42 142.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KZN89287.1 - 3.8e-24 85.9 0.0 5e-23 82.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KZN89287.1 - 1.1e-09 38.3 0.0 9.7e-08 32.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KZN89287.1 - 7.5e-09 36.1 0.0 2e-07 31.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KZN89287.1 - 8.2e-05 22.7 0.0 0.00018 21.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KZN89287.1 - 0.0012 18.6 0.0 0.085 12.6 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 KZN89287.1 - 0.0049 16.4 0.0 0.0092 15.5 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein DEAD PF00270.29 KZN89287.1 - 0.0056 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 KZN89287.1 - 0.028 13.7 0.1 0.9 8.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 KZN89287.1 - 0.16 11.4 0.0 0.34 10.4 0.0 1.6 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain WD40 PF00400.32 KZN89288.1 - 2.1e-17 63.1 1.0 0.19 12.7 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN89288.1 - 0.0027 18.0 0.0 18 5.7 0.0 4.0 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 KZN89288.1 - 0.041 12.8 0.0 0.14 11.1 0.0 1.8 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain PRP38 PF03371.15 KZN89290.1 - 3.9e-64 215.7 0.0 4.9e-64 215.4 0.0 1.0 1 0 0 1 1 1 1 PRP38 family DUF3445 PF11927.8 KZN89291.1 - 2.4e-78 262.8 0.0 3.1e-78 262.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Bac_rhamnosid_N PF08531.10 KZN89291.1 - 0.016 15.0 0.2 0.027 14.3 0.2 1.2 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain Zn_clus PF00172.18 KZN89292.1 - 0.00023 21.2 1.8 0.0004 20.4 1.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KZN89292.1 - 0.0056 15.6 0.2 0.031 13.1 0.2 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain RTA1 PF04479.13 KZN89293.1 - 2e-61 207.2 8.8 2e-61 207.2 8.8 1.8 2 0 0 2 2 2 1 RTA1 like protein Oxidored_molyb PF00174.19 KZN89294.1 - 8.9e-57 191.4 0.0 1.8e-56 190.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KZN89294.1 - 1.1e-36 125.9 0.1 2.9e-36 124.5 0.1 1.7 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.21 KZN89294.1 - 1.1e-24 87.1 0.0 1.1e-24 87.1 0.0 3.1 5 0 0 5 5 5 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KZN89294.1 - 1.1e-22 80.3 0.0 2.1e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 KZN89294.1 - 4.9e-18 65.1 0.0 1.2e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KZN89294.1 - 0.0022 18.2 1.0 0.018 15.2 0.0 2.7 2 1 1 3 3 3 1 Ferric reductase NAD binding domain ANAPC_CDC26 PF10471.9 KZN89294.1 - 2.3 9.1 8.9 10 7.1 8.9 2.2 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Sugar_tr PF00083.24 KZN89295.1 - 1.8e-21 76.5 8.8 3e-19 69.2 8.8 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN89295.1 - 0.2 10.6 17.6 4.6 6.1 17.6 2.0 1 1 0 1 1 1 0 Major Facilitator Superfamily FMO-like PF00743.19 KZN89297.1 - 1.5e-11 43.4 1.1 1.4e-10 40.2 0.2 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KZN89297.1 - 6.7e-07 28.8 0.0 9e-06 25.1 0.0 2.5 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KZN89297.1 - 2.3e-06 27.0 0.0 0.00061 19.0 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KZN89297.1 - 5.1e-06 26.6 0.0 1.5e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KZN89297.1 - 2.2e-05 23.9 0.0 0.00018 20.9 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KZN89297.1 - 0.00073 19.2 0.0 4.5 6.7 0.0 3.3 1 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KZN89297.1 - 0.014 15.4 0.0 0.099 12.6 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 KZN89297.1 - 0.053 12.8 0.0 4.7 6.4 0.0 2.5 3 0 0 3 3 3 0 Thi4 family Glu_dehyd_C PF16912.5 KZN89297.1 - 0.16 11.5 0.0 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus WSC PF01822.19 KZN89299.1 - 8.2e-10 38.7 8.9 8.2e-10 38.7 8.9 2.3 2 1 0 2 2 2 1 WSC domain Podoplanin PF05808.11 KZN89299.1 - 0.0008 19.5 17.7 0.0013 18.8 17.7 1.3 1 0 0 1 1 1 1 Podoplanin RIFIN PF02009.16 KZN89299.1 - 0.0091 15.9 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 Rifin GT87 PF09594.10 KZN89299.1 - 0.016 15.0 2.6 0.18 11.5 0.2 2.1 2 0 0 2 2 2 0 Glycosyltransferase family 87 DUF2207 PF09972.9 KZN89299.1 - 0.043 12.6 0.0 0.059 12.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Herpes_TAF50 PF03326.13 KZN89299.1 - 0.052 12.2 14.5 0.065 11.9 14.5 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Phage_holin_2_4 PF16082.5 KZN89299.1 - 0.069 12.9 0.9 0.21 11.4 0.9 1.8 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Stevor PF17410.2 KZN89299.1 - 0.11 12.1 1.1 0.16 11.5 1.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Apt1 PF10351.9 KZN89299.1 - 0.13 11.1 2.0 0.15 10.9 2.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Adeno_E3_CR2 PF02439.15 KZN89299.1 - 0.18 11.6 1.5 0.38 10.5 1.5 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 HNH_2 PF13391.6 KZN89300.1 - 9.7e-09 35.2 0.1 1.3e-07 31.6 0.0 2.6 2 0 0 2 2 2 1 HNH endonuclease IMS PF00817.20 KZN89301.1 - 1.7e-36 125.5 0.0 1.1e-34 119.6 0.0 2.3 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KZN89301.1 - 1.1e-14 55.1 0.0 2.9e-14 53.8 0.0 1.7 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 KZN89301.1 - 1.7e-12 46.7 1.8 3.6e-12 45.6 1.8 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger DDOST_48kD PF03345.14 KZN89304.1 - 2.4e-157 524.0 0.0 3e-157 523.7 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta NAPRTase_C PF17956.1 KZN89304.1 - 0.028 14.8 0.0 0.076 13.4 0.0 1.8 1 1 0 1 1 1 0 Nicotinate phosphoribosyltransferase C-terminal domain DUF1116 PF06545.11 KZN89304.1 - 0.05 13.1 0.0 0.084 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) Abhydrolase_6 PF12697.7 KZN89305.1 - 8.4e-17 62.5 0.5 1e-16 62.2 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 KZN89305.1 - 0.012 15.3 0.1 0.02 14.5 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF900 PF05990.12 KZN89305.1 - 0.014 14.9 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 KZN89305.1 - 0.014 15.1 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.20 KZN89305.1 - 0.078 12.6 0.0 0.22 11.1 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Pet191_N PF10203.9 KZN89306.1 - 1.9e-29 101.7 4.9 2.5e-29 101.4 4.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 KZN89306.1 - 0.039 14.0 4.6 2.4 8.3 0.7 2.3 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 KZN89306.1 - 0.043 13.8 3.2 1 9.5 0.3 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like PAN_3 PF08277.12 KZN89306.1 - 0.095 12.5 0.7 0.26 11.1 0.3 1.8 2 0 0 2 2 2 0 PAN-like domain Abhydrolase_1 PF00561.20 KZN89307.1 - 2e-23 83.4 0.0 4.9e-23 82.1 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KZN89307.1 - 5.1e-23 80.4 0.0 1.2e-22 79.3 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KZN89307.1 - 4.4e-05 22.9 0.0 0.0082 15.4 0.0 2.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 KZN89307.1 - 0.002 17.8 0.0 0.7 9.5 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Tannase PF07519.11 KZN89309.1 - 2.3e-149 498.3 5.3 2.7e-149 498.1 5.3 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase SNF2_N PF00176.23 KZN89310.1 - 8.4e-75 251.7 0.9 2.3e-74 250.2 0.9 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.25 KZN89310.1 - 3.2e-25 88.0 0.4 1.2e-24 86.2 0.4 2.0 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 KZN89310.1 - 2.7e-21 76.0 2.2 7.2e-20 71.4 0.0 3.8 3 1 1 4 4 4 1 Helicase conserved C-terminal domain HSA PF07529.13 KZN89310.1 - 3.9e-19 68.7 14.5 3.9e-19 68.7 14.5 3.5 4 0 0 4 4 4 1 HSA SnAC PF14619.6 KZN89310.1 - 4.6e-15 56.0 1.6 4.6e-15 56.0 1.6 4.0 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 KZN89310.1 - 2.3e-13 49.7 1.7 2.3e-13 49.7 1.7 2.2 2 0 0 2 2 2 1 QLQ ResIII PF04851.15 KZN89310.1 - 2.9e-10 40.4 0.1 2.9e-10 40.4 0.1 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit BAR PF03114.18 KZN89311.1 - 3e-49 167.8 5.5 3.9e-49 167.5 5.5 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 KZN89311.1 - 2.4e-06 26.9 2.6 3.2e-06 26.5 2.6 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking APG6_N PF17675.1 KZN89311.1 - 0.011 16.3 4.1 0.011 16.3 4.1 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region Ada_Zn_binding PF02805.16 KZN89312.1 - 2.2e-29 101.3 5.4 3.5e-29 100.6 5.4 1.3 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 KZN89312.1 - 3.8e-10 39.6 0.0 7.5e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 KZN89312.1 - 6.1e-05 23.2 0.0 0.00011 22.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Ribosomal_L2_C PF03947.18 KZN89313.1 - 6.9e-43 145.9 5.4 1.2e-42 145.1 5.4 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KZN89313.1 - 2e-12 46.9 0.1 5.9e-12 45.4 0.1 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain WHIM1 PF15612.6 KZN89314.1 - 6.1e-08 32.0 0.0 1.3e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WSD PF15613.6 KZN89314.1 - 0.35 11.4 3.3 7.1 7.2 2.4 3.0 2 1 0 2 2 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DUF1770 PF08589.10 KZN89315.1 - 9.8e-32 109.9 2.0 1.2e-31 109.6 1.3 1.5 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1770) PfkB PF00294.24 KZN89316.1 - 5.1e-68 229.6 0.1 5.7e-68 229.4 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KZN89316.1 - 0.01 15.2 0.0 0.036 13.4 0.0 1.8 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase EST1_DNA_bind PF10373.9 KZN89317.1 - 3.6e-71 239.9 0.4 8.7e-70 235.4 0.0 2.2 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain EST1 PF10374.9 KZN89317.1 - 1.3e-24 87.3 0.6 5e-22 79.0 0.3 2.6 2 0 0 2 2 2 2 Telomerase activating protein Est1 zf-C2H2 PF00096.26 KZN89318.1 - 0.027 14.9 6.0 0.12 12.9 0.8 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KZN89318.1 - 0.044 13.8 0.3 0.13 12.3 0.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KZN89318.1 - 0.18 12.7 3.4 0.84 10.6 0.5 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Fungal_trans PF04082.18 KZN89319.1 - 3.2e-16 59.2 0.8 9e-16 57.7 0.8 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.25 KZN89320.1 - 1.3e-69 234.6 0.0 2.6e-69 233.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN89320.1 - 7.2e-48 163.1 0.0 3.4e-47 160.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 KZN89320.1 - 7.9e-26 90.3 0.0 1.5e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 KZN89320.1 - 1.7e-16 60.4 0.0 3.8e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KZN89320.1 - 1.3e-13 50.8 0.1 6.6e-13 48.6 0.1 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 KZN89320.1 - 7.3e-07 28.8 0.0 0.0019 17.6 0.0 2.3 1 1 1 2 2 2 2 Kinase-like RA PF00788.23 KZN89320.1 - 0.00048 20.7 0.0 0.00089 19.8 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Pkinase_fungal PF17667.1 KZN89320.1 - 0.0025 16.7 0.0 0.0053 15.6 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase tRNA_lig_CPD PF08302.11 KZN89320.1 - 0.069 12.6 0.3 0.11 11.9 0.3 1.2 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain Kdo PF06293.14 KZN89320.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L5_C PF00673.21 KZN89321.1 - 8.2e-29 99.6 0.0 1.3e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KZN89321.1 - 0.00023 21.5 0.0 0.00043 20.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 UCH_1 PF13423.6 KZN89322.1 - 4.1e-16 59.5 0.0 2.2e-13 50.5 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 KZN89322.1 - 5.3e-16 58.9 0.0 1.5e-15 57.4 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pep3_Vps18 PF05131.14 KZN89323.1 - 2e-43 147.8 0.0 1.3e-42 145.1 0.0 2.2 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KZN89323.1 - 2.6e-07 30.6 4.1 0.00014 21.7 0.0 3.5 4 0 0 4 4 4 2 Region in Clathrin and VPS Zn_ribbon_17 PF17120.5 KZN89323.1 - 0.0003 20.4 0.2 0.00062 19.3 0.2 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KZN89323.1 - 0.00079 19.3 0.2 0.0018 18.2 0.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KZN89323.1 - 0.00097 18.8 4.8 0.0031 17.2 4.8 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KZN89323.1 - 0.0025 17.6 0.5 0.0025 17.6 0.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF2175 PF09943.9 KZN89323.1 - 0.0054 17.0 0.3 0.027 14.7 0.1 2.2 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_2 PF13639.6 KZN89323.1 - 0.0093 16.3 1.0 0.024 14.9 1.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KZN89323.1 - 0.032 14.2 0.4 0.079 13.0 0.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 KZN89323.1 - 0.08 12.8 0.1 0.23 11.4 0.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KZN89323.1 - 0.12 12.7 0.4 0.49 10.7 0.6 1.9 2 0 0 2 2 1 0 RING-H2 zinc finger domain Vps39_2 PF10367.9 KZN89323.1 - 0.17 12.4 0.0 0.45 11.0 0.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-C3H2C3 PF17122.5 KZN89323.1 - 1.2 9.2 4.4 0.31 11.1 0.9 1.9 2 0 0 2 2 2 0 Zinc-finger Fungal_trans PF04082.18 KZN89324.1 - 9.6e-09 34.6 1.0 1.5e-08 34.0 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.25 KZN89326.1 - 3e-54 184.1 0.0 4.3e-54 183.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN89326.1 - 8.4e-35 120.3 0.0 1.2e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KZN89326.1 - 1.2e-11 44.4 0.0 2.5e-07 30.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KZN89326.1 - 0.007 15.7 0.1 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Sad1_UNC PF07738.13 KZN89327.1 - 3.8e-30 104.6 0.1 7e-30 103.7 0.1 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal CEP63 PF17045.5 KZN89327.1 - 0.091 12.6 5.3 0.17 11.7 5.3 1.4 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa Spo12 PF05032.12 KZN89328.1 - 8.6e-17 60.7 0.8 1.7e-16 59.8 0.8 1.5 1 0 0 1 1 1 1 Spo12 family Acyl-CoA_dh_1 PF00441.24 KZN89329.1 - 1.7e-30 106.2 1.6 2.8e-30 105.5 1.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KZN89329.1 - 1.5e-20 73.2 0.0 3.1e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KZN89329.1 - 6.3e-14 52.6 0.0 1.2e-13 51.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KZN89329.1 - 1.6e-13 51.1 2.7 2.9e-13 50.2 2.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MMR_HSR1 PF01926.23 KZN89330.1 - 8e-17 61.4 0.2 3.6e-14 52.8 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KZN89330.1 - 2.7e-07 30.2 0.1 1.3e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KZN89330.1 - 1.4e-05 25.0 0.1 0.011 15.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KZN89330.1 - 0.0033 17.5 4.3 0.25 11.4 0.2 3.1 3 1 1 4 4 4 2 Dynamin family AIG1 PF04548.16 KZN89330.1 - 0.005 16.2 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Glyco_transf_25 PF01755.17 KZN89330.1 - 0.045 13.6 1.4 0.14 12.1 1.4 1.7 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) cobW PF02492.19 KZN89330.1 - 0.057 13.0 0.4 0.26 10.8 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain LTV PF04180.14 KZN89331.1 - 7.7e-119 397.8 4.1 8.7e-119 397.7 4.1 1.0 1 0 0 1 1 1 1 Low temperature viability protein HAD_2 PF13419.6 KZN89332.1 - 1.1e-19 71.2 0.0 1.5e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KZN89332.1 - 4.8e-09 36.8 0.1 7.6e-09 36.2 0.1 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KZN89332.1 - 1.8e-07 31.8 0.3 2.4e-07 31.3 0.3 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KZN89332.1 - 0.00077 19.5 0.1 0.0017 18.3 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like PLDc_2 PF13091.6 KZN89333.1 - 3.2e-16 59.4 0.0 4.4e-08 33.1 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KZN89333.1 - 4.4e-09 36.1 0.5 0.0036 17.4 0.4 3.3 2 1 0 2 2 2 2 Phospholipase D Active site motif TPR_14 PF13428.6 KZN89334.1 - 1.7e-08 34.5 27.3 1.1 10.2 1.2 8.7 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 KZN89334.1 - 0.00029 21.1 12.1 5.2 7.4 0.0 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KZN89334.1 - 0.0013 18.8 8.3 24 5.5 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 KZN89334.1 - 0.002 17.9 6.8 2.3 8.2 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KZN89334.1 - 0.0054 16.8 15.9 5.9 7.3 0.0 7.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 KZN89334.1 - 0.0065 16.8 3.0 4.9 7.8 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KZN89334.1 - 0.016 15.8 21.3 0.29 11.8 0.0 6.0 5 1 1 6 6 6 0 Tetratricopeptide repeat PUL PF08324.11 KZN89334.1 - 0.018 14.3 0.1 0.85 8.8 0.0 2.9 3 0 0 3 3 3 0 PUL domain TPR_19 PF14559.6 KZN89334.1 - 0.044 14.3 17.7 0.54 10.8 0.1 6.8 7 1 1 8 8 8 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KZN89334.1 - 0.044 14.0 0.0 0.21 11.9 0.0 2.2 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 RIX1 PF08167.12 KZN89335.1 - 9e-62 208.2 4.7 8.8e-61 204.9 3.4 2.6 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis MBOAT_2 PF13813.6 KZN89336.1 - 3.9e-22 78.3 2.8 3.9e-22 78.3 2.8 2.5 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family adh_short_C2 PF13561.6 KZN89337.1 - 1.2e-46 159.2 0.6 1.4e-46 159.0 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN89337.1 - 4.4e-45 153.5 0.6 5.6e-45 153.2 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN89337.1 - 1.5e-10 41.3 0.7 2.2e-10 40.8 0.7 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KZN89337.1 - 1.3e-05 25.2 0.3 4.1e-05 23.5 0.1 1.9 1 1 1 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KZN89337.1 - 5.8e-05 22.7 0.3 8.3e-05 22.1 0.3 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KZN89337.1 - 0.0001 21.9 0.3 0.00026 20.6 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KZN89337.1 - 0.00017 20.8 0.1 0.00025 20.3 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KZN89337.1 - 0.001 19.3 0.1 0.0016 18.7 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ACT_7 PF13840.6 KZN89337.1 - 0.0041 16.9 0.4 0.051 13.4 0.0 2.7 3 0 0 3 3 3 1 ACT domain DUF1776 PF08643.10 KZN89337.1 - 0.02 14.3 0.0 0.15 11.4 0.0 1.9 1 1 1 2 2 2 0 Fungal family of unknown function (DUF1776) TIP49_C PF17856.1 KZN89337.1 - 0.022 14.9 0.1 0.23 11.6 0.1 2.2 2 0 0 2 2 2 0 TIP49 AAA-lid domain 2OG-FeII_Oxy PF03171.20 KZN89338.1 - 5.4e-13 49.3 0.0 1.1e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KZN89338.1 - 3.4e-10 40.7 0.0 8.1e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Ribonuc_L-PSP PF01042.21 KZN89339.1 - 3.1e-22 78.9 0.0 3.8e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF5130 PF17174.4 KZN89339.1 - 0.019 15.2 0.0 0.023 14.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5130) HpcH_HpaI PF03328.14 KZN89340.1 - 1.6e-32 112.5 0.2 2e-32 112.1 0.2 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.18 KZN89340.1 - 0.0019 17.4 0.1 0.05 12.7 0.1 2.5 1 1 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain MFS_1 PF07690.16 KZN89341.1 - 2.7e-39 135.1 17.7 2.7e-39 135.1 17.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 KZN89342.1 - 1.4e-17 63.6 1.8 1.5e-17 63.5 0.9 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KZN89342.1 - 0.00018 21.8 14.1 0.032 14.7 2.8 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KZN89342.1 - 0.0057 17.4 17.3 0.022 15.6 1.9 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KZN89342.1 - 0.13 12.4 0.8 0.4 10.8 0.8 1.9 1 0 0 1 1 1 0 Zinc ribbon domain zf-met PF12874.7 KZN89342.1 - 0.49 10.9 6.3 8 7.0 0.7 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type GAGA PF09237.11 KZN89342.1 - 1 9.2 6.0 2.6 7.9 0.6 2.6 1 1 1 2 2 2 0 GAGA factor zf-BED PF02892.15 KZN89342.1 - 4.1 7.5 5.7 5.7 7.0 1.5 2.8 1 1 1 2 2 2 0 BED zinc finger SNF2_N PF00176.23 KZN89343.1 - 1.4e-65 221.4 0.0 2.1e-65 220.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KZN89343.1 - 2.3e-15 56.9 0.0 5.4e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIRAN PF08797.11 KZN89343.1 - 4.1e-14 52.3 0.0 9.3e-14 51.1 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain zf-C3HC4_2 PF13923.6 KZN89343.1 - 1.5e-10 40.8 10.0 3.3e-10 39.6 10.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KZN89343.1 - 5.4e-10 39.0 9.1 5.4e-10 39.0 9.1 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KZN89343.1 - 7.9e-09 35.3 10.2 7.9e-09 35.3 10.2 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KZN89343.1 - 1.1e-08 35.2 9.6 1.1e-08 35.2 9.6 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KZN89343.1 - 4.1e-07 29.9 6.1 9.5e-07 28.7 6.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KZN89343.1 - 4.5e-07 29.7 8.7 1.1e-06 28.5 8.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KZN89343.1 - 1.4e-06 28.3 9.1 2.8e-06 27.4 9.1 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KZN89343.1 - 1.7e-05 25.0 6.0 4.6e-05 23.6 6.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KZN89343.1 - 2.1e-05 24.3 8.1 2.1e-05 24.3 8.1 1.7 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KZN89343.1 - 0.0031 17.3 5.4 0.007 16.2 5.4 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 KZN89343.1 - 0.043 14.0 5.8 0.12 12.5 5.8 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KZN89343.1 - 0.05 13.4 7.8 0.11 12.2 7.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain U-box PF04564.15 KZN89343.1 - 0.17 12.1 0.4 0.85 9.8 0.0 2.3 3 0 0 3 3 2 0 U-box domain zf-RING_11 PF17123.5 KZN89343.1 - 0.74 9.6 3.8 2.6 7.9 3.8 2.0 1 0 0 1 1 1 0 RING-like zinc finger DUF1272 PF06906.11 KZN89343.1 - 0.88 9.7 5.2 1.8 8.7 5.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Peptidase_S49_N PF08496.10 KZN89343.1 - 9.5 6.3 6.9 23 5.0 6.9 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Fungal_trans_2 PF11951.8 KZN89345.1 - 2.6e-09 36.4 1.8 6.7e-09 35.0 1.3 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN89345.1 - 0.00091 19.3 6.2 0.002 18.2 6.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transferase PF02458.15 KZN89346.1 - 5.7e-07 28.5 0.0 1.1e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 Transferase family DUF3656 PF12392.8 KZN89346.1 - 0.055 14.1 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Collagenase SNF2_N PF00176.23 KZN89347.1 - 6.1e-44 150.2 0.0 9.6e-44 149.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KZN89347.1 - 8.9e-20 71.1 0.0 1.8e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KZN89347.1 - 6.9e-08 32.0 0.0 1.2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KZN89347.1 - 7.4e-05 22.8 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KZN89347.1 - 0.0019 17.9 0.0 0.14 11.8 0.0 2.2 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DEAD PF00270.29 KZN89347.1 - 0.027 14.3 0.0 0.1 12.3 0.0 1.9 1 1 0 1 1 1 0 DEAD/DEAH box helicase GSH_synth_ATP PF03917.17 KZN89348.1 - 1.4e-131 438.7 0.0 1.6e-131 438.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KZN89348.1 - 6.6e-29 100.4 0.0 1.1e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase FMN_dh PF01070.18 KZN89349.1 - 2.2e-104 349.3 0.0 2.5e-104 349.0 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KZN89349.1 - 8.2e-07 28.3 0.1 0.0002 20.5 0.0 2.6 3 0 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KZN89349.1 - 1.9e-06 27.3 0.1 3.2e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KZN89349.1 - 0.0065 15.9 0.1 0.01 15.3 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 KZN89349.1 - 0.018 14.5 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein Bestrophin PF01062.21 KZN89350.1 - 2.1e-37 129.1 0.0 4.3e-37 128.1 0.0 1.4 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel T6SS_VasE PF05936.12 KZN89350.1 - 0.046 12.4 0.0 0.066 11.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE Sugar_tr PF00083.24 KZN89352.1 - 3.1e-93 313.1 17.9 3.8e-93 312.8 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN89352.1 - 1.3e-12 47.3 43.7 2.7e-09 36.4 30.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Aminotran_3 PF00202.21 KZN89354.1 - 3.5e-125 417.8 0.0 4.1e-125 417.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Spt4 PF06093.13 KZN89355.1 - 2.8e-32 110.7 0.3 3.3e-32 110.4 0.3 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger TackOD1 PF18551.1 KZN89355.1 - 0.069 12.8 1.4 0.093 12.4 1.4 1.2 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 PPP5 PF08321.12 KZN89356.1 - 6.7e-32 109.6 0.7 1.2e-31 108.9 0.1 1.7 2 0 0 2 2 2 1 PPP5 TPR repeat region Metallophos PF00149.28 KZN89356.1 - 2.7e-31 109.7 0.0 3.9e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 KZN89356.1 - 2.6e-09 36.5 1.9 0.00013 21.7 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KZN89356.1 - 4.4e-09 35.8 2.0 0.058 13.5 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KZN89356.1 - 1.1e-06 28.2 2.2 0.012 15.3 0.3 3.6 2 1 2 4 4 4 2 TPR repeat TPR_19 PF14559.6 KZN89356.1 - 0.00016 22.1 0.3 1.1 9.8 0.0 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KZN89356.1 - 0.00055 20.0 0.0 0.28 11.4 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KZN89356.1 - 0.00073 20.1 4.3 1.2 9.8 0.1 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KZN89356.1 - 0.0014 18.9 0.3 1.9 9.0 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KZN89356.1 - 0.0039 17.3 0.4 1.5 9.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KZN89356.1 - 0.09 12.9 0.2 0.21 11.7 0.2 1.6 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 KZN89356.1 - 0.63 10.2 2.6 9.2 6.4 0.2 2.8 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 KZN89356.1 - 1.3 10.0 3.5 46 5.2 0.3 3.9 4 1 1 5 5 4 0 Tetratricopeptide repeat DUF89 PF01937.19 KZN89357.1 - 7.4e-121 403.4 0.0 8.3e-121 403.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Cytochrom_C550 PF14495.6 KZN89357.1 - 0.082 12.6 0.0 0.34 10.6 0.0 1.9 2 0 0 2 2 2 0 Cytochrome c-550 domain Cut12 PF11500.8 KZN89358.1 - 3.7e-50 169.6 7.8 3.7e-50 169.6 7.8 4.8 4 1 1 5 5 5 1 Spindle pole body formation-associated protein Lebercilin PF15619.6 KZN89358.1 - 1.3 8.7 48.3 0.99 9.0 26.6 3.0 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Peptidase_S46 PF10459.9 KZN89358.1 - 3 6.4 25.2 4.5 5.8 25.2 1.2 1 0 0 1 1 1 0 Peptidase S46 DUF2730 PF10805.8 KZN89358.1 - 5.9 7.0 19.9 0.58 10.3 1.6 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) DUF4267 PF14087.6 KZN89359.1 - 8.2e-30 103.2 2.9 9.9e-30 102.9 2.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) HGTP_anticodon2 PF12745.7 KZN89360.1 - 4.9e-83 278.7 3.1 4.9e-83 278.7 3.1 2.0 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 KZN89360.1 - 8.3e-69 231.9 0.0 3.2e-36 125.1 0.0 4.1 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KZN89360.1 - 4.2e-36 124.5 0.0 1.7e-18 66.9 0.0 3.9 4 0 0 4 4 4 3 Protein tyrosine kinase RWD PF05773.22 KZN89360.1 - 3e-16 59.7 0.0 1.1e-15 57.9 0.0 2.1 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.6 KZN89360.1 - 5.5e-13 48.9 1.1 1.7e-11 44.0 0.0 2.3 2 0 0 2 2 2 1 Histidyl-tRNA synthetase APH PF01636.23 KZN89360.1 - 0.00077 19.5 8.6 0.0013 18.8 0.1 3.3 3 0 0 3 3 3 1 Phosphotransferase enzyme family HGTP_anticodon PF03129.20 KZN89360.1 - 0.0029 17.7 0.1 0.0073 16.4 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain FTA2 PF13095.6 KZN89360.1 - 0.0043 16.7 0.0 0.061 12.9 0.0 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 DUF1682 PF07946.14 KZN89360.1 - 0.016 14.4 3.6 0.028 13.7 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Kinase-like PF14531.6 KZN89360.1 - 0.082 12.2 0.0 4.6 6.5 0.0 2.5 2 0 0 2 2 2 0 Kinase-like Torus PF16131.5 KZN89362.1 - 1.3e-16 61.3 0.1 1.9e-15 57.5 0.0 2.2 1 1 1 2 2 2 2 Torus domain RRM_1 PF00076.22 KZN89362.1 - 0.00062 19.5 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KZN89362.1 - 0.016 15.2 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif MMR_HSR1_Xtn PF16897.5 KZN89363.1 - 1.7e-34 118.1 2.2 7.7e-34 115.9 0.2 2.2 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KZN89363.1 - 1.4e-20 73.5 0.0 2.7e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 KZN89363.1 - 1.4e-18 66.7 0.1 3e-18 65.6 0.1 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KZN89363.1 - 2.2e-12 46.8 0.0 3.6e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KZN89363.1 - 7.1e-05 22.9 0.2 0.044 13.8 0.0 2.3 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 KZN89363.1 - 0.027 13.4 0.2 0.1 11.5 0.1 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 KZN89363.1 - 0.044 13.1 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 AIG1 family MCM PF00493.23 KZN89363.1 - 0.044 12.9 0.0 0.1 11.7 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain GATase PF00117.28 KZN89364.1 - 4.3e-46 157.1 0.0 6.1e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 KZN89364.1 - 9.5e-46 154.8 0.0 1.9e-45 153.8 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 KZN89364.1 - 2.5e-05 24.2 0.2 0.00075 19.3 0.1 2.4 1 1 0 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.24 KZN89364.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family SnoaL PF07366.12 KZN89365.1 - 0.03 14.1 0.2 0.052 13.3 0.2 1.6 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase Zn_clus PF00172.18 KZN89366.1 - 1.3e-08 34.8 12.4 2.4e-08 33.9 12.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN89366.1 - 3.4e-05 23.0 0.0 7e-05 22.0 0.0 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain DnaJ_C PF01556.18 KZN89367.1 - 2.8e-34 118.3 0.2 3.6e-34 118.0 0.2 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KZN89367.1 - 6.5e-27 93.4 5.8 1e-26 92.8 5.8 1.3 1 0 0 1 1 1 1 DnaJ domain PIG-X PF08320.12 KZN89368.1 - 9.9e-69 231.5 0.0 1.7e-68 230.7 0.0 1.4 1 0 0 1 1 1 1 PIG-X / PBN1 Abhydrolase_3 PF07859.13 KZN89369.1 - 5e-40 137.6 0.0 6.2e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KZN89369.1 - 0.0024 17.2 0.0 0.054 12.8 0.0 2.2 1 1 0 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 KZN89369.1 - 0.0047 16.5 0.0 0.0082 15.7 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Say1_Mug180 PF10340.9 KZN89369.1 - 0.062 12.1 0.0 0.088 11.6 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase Peptidase_S10 PF00450.22 KZN89370.1 - 2.9e-51 175.2 0.1 8.2e-51 173.7 0.1 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase CathepsinC_exc PF08773.11 KZN89370.1 - 0.076 13.3 0.6 10 6.4 0.0 3.2 3 0 0 3 3 3 0 Cathepsin C exclusion domain PARP PF00644.20 KZN89371.1 - 4.5e-35 121.0 0.0 1.1e-34 119.8 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain BRCT PF00533.26 KZN89371.1 - 4.4e-05 23.8 0.1 0.00013 22.3 0.1 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KZN89371.1 - 0.0013 18.6 0.1 0.004 17.1 0.1 1.8 2 0 0 2 2 2 1 twin BRCT domain PARP_reg PF02877.14 KZN89371.1 - 0.038 14.1 1.7 0.05 13.7 0.4 1.8 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain PBP PF01161.20 KZN89372.1 - 1.5e-14 54.4 0.1 1.9e-14 54.1 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein p450 PF00067.22 KZN89373.1 - 1.4e-18 66.9 0.0 1.7e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BTB PF00651.31 KZN89374.1 - 2.6e-06 27.6 0.0 1.9e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Ysc84 PF04366.12 KZN89375.1 - 4.2e-47 159.1 0.0 6.8e-47 158.4 0.0 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator ETF PF01012.21 KZN89376.1 - 9e-44 149.5 0.2 1.1e-43 149.3 0.2 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Ribosomal_L20 PF00453.18 KZN89376.1 - 0.035 14.2 0.0 0.062 13.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L20 FAD_binding_1 PF00667.20 KZN89377.1 - 3.8e-32 111.7 0.0 6e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KZN89377.1 - 4.2e-30 104.8 0.0 6.4e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KZN89377.1 - 9.8e-15 55.1 0.0 3.2e-14 53.5 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KZN89377.1 - 0.0073 16.6 0.0 0.031 14.5 0.0 2.1 2 1 1 3 3 3 1 Flavodoxin domain Flavodoxin_3 PF12641.7 KZN89377.1 - 0.024 14.3 0.0 0.063 13.0 0.0 1.6 2 0 0 2 2 2 0 Flavodoxin domain RNA_pol_3_Rpc31 PF11705.8 KZN89378.1 - 4.4e-61 207.0 12.6 5.6e-61 206.7 12.6 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.13 KZN89378.1 - 0.027 14.5 0.9 0.03 14.3 0.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MitMem_reg PF13012.6 KZN89380.1 - 3.4e-12 46.8 6.8 8.9e-12 45.4 6.8 1.7 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KZN89380.1 - 3.2e-08 33.6 0.0 8.3e-08 32.2 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Herpes_UL35 PF04496.12 KZN89380.1 - 0.13 12.6 0.2 0.42 10.9 0.0 1.9 2 0 0 2 2 2 0 Herpesvirus UL35 family Solute_trans_a PF03619.16 KZN89381.1 - 1.5e-89 300.1 21.4 1.8e-89 299.8 21.4 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF1129 PF06570.11 KZN89381.1 - 6.8 6.1 11.0 1.3 8.4 4.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) SAP PF02037.27 KZN89382.1 - 1.9e-09 37.1 0.2 3.3e-09 36.3 0.2 1.4 1 0 0 1 1 1 1 SAP domain RSB_motif PF16294.5 KZN89382.1 - 2.3e-07 31.0 0.2 2.3e-07 31.0 0.2 4.9 3 2 0 4 4 4 1 RNSP1-SAP18 binding (RSB) motif Glyco_hydro_67M PF07488.12 KZN89383.1 - 1e-147 491.4 0.2 1.6e-147 490.8 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 KZN89383.1 - 7.6e-91 303.6 4.0 1.1e-90 303.1 4.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 KZN89383.1 - 5.4e-34 117.1 0.0 1e-33 116.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.15 KZN89383.1 - 0.0026 18.5 0.0 0.0077 17.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DUF4838 PF16126.5 KZN89383.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4838) Ribosomal_L7Ae PF01248.26 KZN89384.1 - 4e-25 87.4 0.0 4.5e-25 87.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Abhydrolase_1 PF00561.20 KZN89385.1 - 4.3e-46 157.6 0.0 1.7e-45 155.7 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KZN89385.1 - 0.001 19.7 4.0 0.0024 18.5 4.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Glyco_hydro_3_C PF01915.22 KZN89387.1 - 8.6e-60 202.2 0.0 1.4e-59 201.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KZN89387.1 - 9.2e-51 173.1 0.0 1.5e-50 172.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KZN89387.1 - 1.1e-22 79.9 2.3 2.8e-22 78.6 1.6 2.1 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 KZN89387.1 - 4.3e-16 59.0 0.1 8.5e-16 58.1 0.1 1.5 1 0 0 1 1 1 1 PA14 domain THOC2_N PF16134.5 KZN89388.1 - 7.6e-248 824.3 0.0 1.2e-247 823.6 0.0 1.3 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 KZN89388.1 - 8.5e-105 350.3 0.1 1.3e-104 349.6 0.1 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 KZN89388.1 - 3.1e-30 104.1 0.2 1.3e-29 102.0 0.0 2.2 2 0 0 2 2 2 1 Transcription- and export-related complex subunit Ant_C PF05586.11 KZN89388.1 - 0.087 13.4 0.2 6.4 7.5 0.1 2.7 2 0 0 2 2 2 0 Anthrax receptor C-terminus region DUF5486 PF17588.2 KZN89388.1 - 2.5 8.1 4.4 22 5.0 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5486) Epimerase PF01370.21 KZN89389.1 - 3.2e-09 36.6 0.1 0.00025 20.6 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KZN89389.1 - 6.4e-06 25.9 0.1 9.6e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KZN89389.1 - 6.8e-06 26.1 0.0 1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KZN89389.1 - 5.3e-05 23.6 0.0 0.00012 22.5 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain TMV_coat PF00721.21 KZN89389.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Virus coat protein (TMV like) GFA PF04828.14 KZN89390.1 - 8.8e-17 61.2 0.3 1.3e-16 60.7 0.3 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DPBB_1 PF03330.18 KZN89390.1 - 0.11 12.8 0.3 0.31 11.3 0.1 1.9 1 1 1 2 2 2 0 Lytic transglycolase zf-TFIIB PF13453.6 KZN89390.1 - 0.16 11.4 0.1 0.16 11.4 0.1 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger Nudix_N_2 PF14803.6 KZN89390.1 - 0.48 10.4 0.1 0.48 10.4 0.1 3.7 4 0 0 4 4 4 0 Nudix N-terminal DiS_P_DiS PF06750.13 KZN89390.1 - 1.2 9.3 4.9 8.8 6.5 4.9 2.0 1 1 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain Vps5 PF09325.10 KZN89391.1 - 1.8e-14 53.9 0.5 2.8e-14 53.3 0.5 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KZN89391.1 - 6.2e-10 39.1 0.0 1.2e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 PX domain KAsynt_C_assoc PF16197.5 KZN89391.1 - 0.14 12.7 0.4 0.3 11.6 0.4 1.5 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension GTP_EFTU PF00009.27 KZN89392.1 - 3.7e-54 183.2 0.0 5.7e-54 182.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KZN89392.1 - 9.3e-26 89.7 0.0 1.9e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KZN89392.1 - 3.1e-16 59.2 0.1 2.1e-09 37.3 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KZN89392.1 - 4.9e-06 26.8 0.0 1.2e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KZN89392.1 - 0.0025 17.6 0.0 0.0052 16.6 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_IV PF03764.18 KZN89392.1 - 0.071 12.9 0.4 0.45 10.3 0.0 2.4 3 0 0 3 3 3 0 Elongation factor G, domain IV DUF2383 PF09537.10 KZN89392.1 - 0.1 12.9 0.1 0.3 11.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) ArfGap PF01412.18 KZN89393.1 - 3.4e-30 104.5 0.1 7.1e-30 103.5 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RRM_1 PF00076.22 KZN89394.1 - 3.6e-32 110.0 0.3 4.6e-15 55.2 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KZN89394.1 - 1.3e-05 25.2 0.0 0.017 15.2 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 KZN89394.1 - 0.0011 18.5 0.0 1.9 8.1 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KZN89394.1 - 0.003 17.8 1.8 0.81 9.9 0.3 3.1 2 2 1 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter RRM_occluded PF16842.5 KZN89394.1 - 0.015 15.1 0.1 5.8 6.8 0.0 3.1 3 0 0 3 3 3 0 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 KZN89394.1 - 0.094 12.5 0.0 0.8 9.5 0.0 2.2 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain FXMRP1_C_core PF12235.8 KZN89394.1 - 0.17 12.5 10.8 0.43 11.2 10.8 1.6 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal DNA_ligase_IV PF11411.8 KZN89394.1 - 0.26 11.4 0.8 23 5.2 0.1 2.4 2 0 0 2 2 2 0 DNA ligase IV DUF2985 PF11204.8 KZN89395.1 - 1.3e-22 79.7 2.8 2.8e-22 78.6 2.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) NAD_binding_10 PF13460.6 KZN89396.1 - 7.5e-06 26.0 0.0 0.00048 20.1 0.0 3.0 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KZN89396.1 - 0.0025 17.4 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Hydrophobin PF01185.18 KZN89397.1 - 1.7e-09 38.1 7.2 2.3e-09 37.8 7.2 1.2 1 0 0 1 1 1 1 Fungal hydrophobin SMI1_KNR4 PF09346.10 KZN89398.1 - 0.0043 17.4 0.0 0.011 16.2 0.0 1.7 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) PAD_porph PF04371.15 KZN89399.1 - 5.3e-91 305.2 0.0 6e-91 305.1 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase DUF150 PF02576.17 KZN89399.1 - 0.1 13.0 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 RimP N-terminal domain CysA_C_terminal PF17850.1 KZN89399.1 - 0.13 12.8 0.2 0.56 10.8 0.0 2.2 2 0 0 2 2 2 0 CysA C-terminal regulatory domain Orn_Arg_deC_N PF02784.16 KZN89400.1 - 1.3e-63 214.7 0.0 1.7e-63 214.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KZN89400.1 - 1.3e-15 57.4 0.0 1.4e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Opi1 PF08618.10 KZN89401.1 - 4.9e-48 164.4 12.3 1.1e-34 120.5 3.1 3.2 1 1 2 3 3 3 3 Transcription factor Opi1 DUF4726 PF15855.5 KZN89401.1 - 0.039 14.2 0.0 0.15 12.3 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4726) PRIMA1 PF16101.5 KZN89401.1 - 1.5 8.8 4.9 1.2 9.2 0.9 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 MCPVI PF02993.14 KZN89401.1 - 9.1 6.0 13.0 0.048 13.5 1.8 2.7 2 1 1 3 3 3 0 Minor capsid protein VI RdRP PF05183.12 KZN89402.1 - 1.9e-127 426.4 0.0 2.8e-127 425.9 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Sugar_tr PF00083.24 KZN89403.1 - 2.1e-08 33.5 0.2 2.4e-08 33.3 0.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter PRELI PF04707.14 KZN89406.1 - 1.2e-24 86.9 0.0 5.9e-21 74.9 0.0 2.2 2 0 0 2 2 2 2 PRELI-like family NmrA PF05368.13 KZN89407.1 - 6.1e-27 94.7 0.0 7.8e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KZN89407.1 - 2e-15 57.1 0.0 2.8e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KZN89407.1 - 1.9e-06 28.1 0.1 3.2e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KZN89407.1 - 0.0026 18.2 0.0 0.0044 17.5 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 KZN89407.1 - 0.0043 17.0 0.0 0.0069 16.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KZN89407.1 - 0.0059 16.1 0.0 0.03 13.8 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ribosomal_S13 PF00416.22 KZN89407.1 - 0.17 12.3 0.0 0.27 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S13/S18 Prenyltrans PF00432.21 KZN89408.1 - 0.044 13.5 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat Thg1C PF14413.6 KZN89408.1 - 0.14 12.3 0.7 0.24 11.6 0.7 1.5 1 1 0 1 1 1 0 Thg1 C terminal domain adh_short_C2 PF13561.6 KZN89410.1 - 2.6e-54 184.3 5.3 5.4e-54 183.2 5.3 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN89410.1 - 1.8e-35 122.2 5.6 9.7e-35 119.8 5.6 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN89410.1 - 8e-08 32.4 4.9 1.9e-06 27.9 4.9 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KZN89410.1 - 0.00057 19.4 0.4 0.048 13.1 0.1 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KZN89410.1 - 0.0071 15.7 0.8 0.02 14.3 0.6 1.8 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KZN89410.1 - 0.031 14.8 1.2 0.064 13.8 1.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent YjeF_N PF03853.15 KZN89410.1 - 0.051 13.5 0.3 0.11 12.4 0.3 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus THF_DHG_CYH_C PF02882.19 KZN89410.1 - 0.072 12.4 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 KZN89410.1 - 0.11 12.3 1.2 0.19 11.6 1.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain STALD PF18185.1 KZN89410.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Sir2- and TIR-associating SLOG family MCR_alpha PF02249.17 KZN89410.1 - 0.19 12.2 2.2 0.32 11.4 1.2 1.8 1 1 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain Voldacs PF03517.13 KZN89412.1 - 2.8e-24 85.8 2.9 2.8e-24 85.8 2.9 2.7 3 1 0 3 3 3 1 Regulator of volume decrease after cellular swelling Nse5 PF08691.10 KZN89413.1 - 0.15 10.7 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 Fungal_trans_2 PF11951.8 KZN89414.1 - 8.5e-34 117.0 0.1 1.4e-33 116.2 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN89414.1 - 4.2e-08 33.2 9.4 7.4e-08 32.4 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fmp27_GFWDK PF10347.9 KZN89414.1 - 0.038 14.1 0.0 0.089 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Axin_b-cat_bind PF08833.10 KZN89414.1 - 0.35 11.0 5.1 6 7.1 1.8 2.7 2 0 0 2 2 2 0 Axin beta-catenin binding domain CM_2 PF01817.21 KZN89415.1 - 4.9e-12 46.0 0.0 6e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Chorismate mutase type II Osmo_CC PF08946.10 KZN89415.1 - 0.032 14.5 0.2 0.05 13.8 0.2 1.3 1 0 0 1 1 1 0 Osmosensory transporter coiled coil FlaC_arch PF05377.11 KZN89415.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) adh_short_C2 PF13561.6 KZN89416.1 - 7e-63 212.3 0.0 9.1e-63 211.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN89416.1 - 4.1e-51 173.2 0.1 5.2e-51 172.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN89416.1 - 2.6e-05 24.2 0.0 6.1e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KZN89416.1 - 0.013 14.9 0.1 0.037 13.5 0.0 1.7 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Dyp_perox PF04261.12 KZN89418.1 - 8.6e-10 38.1 0.1 1.4e-06 27.5 0.0 2.9 3 0 0 3 3 3 2 Dyp-type peroxidase family DUF1929 PF09118.11 KZN89419.1 - 1.7e-22 79.5 0.0 4.2e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 KZN89419.1 - 1.6e-16 59.9 3.1 0.00094 19.4 0.1 4.6 3 1 1 4 4 4 3 Kelch motif F5_F8_type_C PF00754.25 KZN89419.1 - 1.1e-15 57.9 0.1 3.3e-15 56.3 0.1 1.9 1 0 0 1 1 1 1 F5/8 type C domain Kelch_1 PF01344.25 KZN89419.1 - 3.3e-14 52.2 0.5 2.2e-05 23.9 0.1 4.5 4 0 0 4 4 4 3 Kelch motif Glyoxal_oxid_N PF07250.11 KZN89419.1 - 3.5e-09 36.2 0.2 2e-07 30.4 0.2 2.4 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus Kelch_4 PF13418.6 KZN89419.1 - 3.8e-09 36.4 8.0 0.0035 17.3 0.0 5.8 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 KZN89419.1 - 1.2e-07 31.5 0.4 0.72 9.9 0.0 5.3 5 0 0 5 5 5 3 Kelch motif ANAPC10 PF03256.16 KZN89419.1 - 0.0017 18.0 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) XRCC1_N PF01834.16 KZN89419.1 - 0.023 14.7 0.1 0.042 13.8 0.1 1.3 1 0 0 1 1 1 0 XRCC1 N terminal domain Aldo_ket_red PF00248.21 KZN89421.1 - 5.5e-71 239.1 0.0 6.5e-71 238.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Phage_ABA_S PF18066.1 KZN89421.1 - 0.036 14.7 0.1 0.74 10.5 0.0 2.4 2 0 0 2 2 2 0 Phage ABA sandwich domain DUF1996 PF09362.10 KZN89423.1 - 2.2e-82 276.5 0.2 2.2e-82 276.5 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) zf-C3Hc3H PF13891.6 KZN89423.1 - 0.05 14.0 0.9 0.11 12.8 0.9 1.6 1 0 0 1 1 1 0 Potential DNA-binding domain INO80_Ies4 PF08193.11 KZN89423.1 - 0.47 10.4 7.1 0.75 9.7 7.1 1.3 1 0 0 1 1 1 0 INO80 complex subunit Ies4 Metallophos PF00149.28 KZN89425.1 - 2e-37 129.7 0.0 3.7e-37 128.8 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PHD20L1_u1 PF16660.5 KZN89425.1 - 0.063 14.0 0.5 0.56 11.0 0.0 2.5 2 0 0 2 2 2 0 PHD finger protein 20-like protein 1 Beta-lactamase PF00144.24 KZN89426.1 - 6.4e-40 137.4 0.0 1.2e-39 136.5 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase DUF1993 PF09351.10 KZN89427.1 - 1.9e-48 164.6 0.0 2.2e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) PipA PF07108.11 KZN89427.1 - 0.053 13.0 0.0 0.071 12.6 0.0 1.2 1 0 0 1 1 1 0 PipA protein HSP33 PF01430.19 KZN89427.1 - 0.15 11.5 0.3 3.9 6.8 0.0 2.0 1 1 1 2 2 2 0 Hsp33 protein Exog_C PF18026.1 KZN89427.1 - 0.17 11.9 0.1 0.33 11.0 0.1 1.5 1 0 0 1 1 1 0 Endo/exonuclease (EXOG) C-terminal domain CBM-like PF14683.6 KZN89428.1 - 0.017 15.0 0.8 0.039 13.8 0.8 1.7 1 1 0 1 1 1 0 Polysaccharide lyase family 4, domain III BCS1_N PF08740.11 KZN89429.1 - 8.4e-32 110.7 0.2 1.3e-31 110.1 0.2 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KZN89429.1 - 4.7e-20 72.4 0.0 1.4e-19 70.8 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KZN89429.1 - 0.01 16.3 0.1 0.023 15.1 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KZN89429.1 - 0.015 15.3 0.0 0.04 13.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KZN89429.1 - 0.021 14.6 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 KZN89429.1 - 0.054 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 KaiC Polyoma_lg_T_C PF06431.11 KZN89429.1 - 0.063 12.1 0.0 0.093 11.6 0.0 1.1 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus AAA_25 PF13481.6 KZN89429.1 - 0.087 12.4 0.0 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KZN89429.1 - 0.094 12.1 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KZN89429.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 KZN89429.1 - 0.12 12.6 0.1 0.36 11.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KZN89429.1 - 0.13 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_29 PF13555.6 KZN89429.1 - 0.17 11.7 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KZN89429.1 - 0.17 12.0 0.1 1 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KZN89429.1 - 0.18 10.9 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 MFS_1 PF07690.16 KZN89430.1 - 2.3e-34 118.9 22.3 3.2e-34 118.4 22.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily YgaB PF14182.6 KZN89431.1 - 0.17 12.3 1.4 0.37 11.2 1.4 1.5 1 0 0 1 1 1 0 YgaB-like protein PDDEXK_1 PF12705.7 KZN89432.1 - 0.019 14.9 0.0 0.049 13.5 0.0 1.7 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily DUF3716 PF12511.8 KZN89433.1 - 3.4e-14 52.6 6.7 4.7e-14 52.2 6.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) AA_permease_2 PF13520.6 KZN89434.1 - 2.6e-44 151.7 52.1 3.3e-44 151.4 52.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN89434.1 - 2.8e-16 59.2 41.7 4e-16 58.7 41.7 1.1 1 0 0 1 1 1 1 Amino acid permease PNTB PF02233.16 KZN89435.1 - 1.2e-171 571.6 22.8 1.2e-171 571.6 22.8 2.0 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 KZN89435.1 - 5.3e-74 248.1 0.1 5.3e-74 248.1 0.1 2.3 2 0 0 2 2 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KZN89435.1 - 4.6e-44 150.0 0.0 1.2e-43 148.7 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 KZN89435.1 - 3.8e-30 104.2 3.6 3.8e-30 104.2 3.6 4.6 2 1 1 4 4 3 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 KZN89435.1 - 5.1e-05 22.7 0.1 0.13 11.6 0.0 3.0 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.22 KZN89435.1 - 0.0012 18.6 0.2 0.0069 16.1 0.2 2.3 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain ADH_zinc_N PF00107.26 KZN89435.1 - 0.033 14.1 0.1 0.17 11.9 0.1 2.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 KZN89435.1 - 0.053 12.7 0.1 0.053 12.7 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KZN89435.1 - 0.11 11.5 0.5 0.19 10.8 0.5 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KZN89435.1 - 0.39 11.0 2.6 0.41 10.9 0.2 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain PRIMA1 PF16101.5 KZN89435.1 - 0.72 9.9 3.0 2.5 8.1 3.0 1.9 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 ELO PF01151.18 KZN89437.1 - 1.8e-61 207.8 24.3 2.1e-61 207.6 24.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF1240 PF06836.12 KZN89437.1 - 6.9 7.3 15.8 2.5 8.7 4.7 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF1240) COX5A PF02284.16 KZN89438.1 - 3.3e-37 126.6 0.2 3.3e-37 126.6 0.2 1.4 2 0 0 2 2 2 1 Cytochrome c oxidase subunit Va Glyco_transf_15 PF01793.16 KZN89439.1 - 8.3e-113 376.9 6.5 9.6e-113 376.7 6.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_25 PF01755.17 KZN89439.1 - 0.0045 16.9 0.5 0.0063 16.4 0.5 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) GCP_N_terminal PF17681.1 KZN89440.1 - 2.7e-34 119.2 3.3 3.4e-34 118.9 1.3 2.1 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KZN89440.1 - 1.7e-25 90.2 4.9 3.7e-25 89.1 4.9 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 KZN89440.1 - 9.3e-12 44.1 0.0 2.7e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 gamma-Tubulin ring complex non-core subunit mod21 tRNA-synt_1b PF00579.25 KZN89441.1 - 1.9e-53 181.7 0.0 2.4e-53 181.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Epimerase PF01370.21 KZN89441.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GATase_5 PF13507.6 KZN89442.1 - 1.3e-98 329.2 0.0 2e-98 328.6 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KZN89442.1 - 3.5e-39 134.5 0.5 2.4e-24 86.2 0.4 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 KZN89442.1 - 4.3e-33 113.7 0.0 8.2e-33 112.8 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 KZN89442.1 - 4.3e-22 78.4 0.0 1e-21 77.2 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 KZN89442.1 - 0.042 14.5 0.1 0.22 12.2 0.0 2.3 2 0 0 2 2 2 0 AIR synthase related protein, N-terminal domain LEA_3 PF03242.13 KZN89442.1 - 0.097 13.4 0.1 0.32 11.7 0.1 1.9 1 0 0 1 1 1 0 Late embryogenesis abundant protein Fungal_trans PF04082.18 KZN89443.1 - 5.8e-31 107.5 0.3 1.2e-30 106.5 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN89443.1 - 1.7e-09 37.7 11.3 3e-09 36.9 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CdvA PF18822.1 KZN89443.1 - 0.018 14.9 0.0 3.5 7.5 0.0 2.3 2 0 0 2 2 2 0 CdvA-like coiled-coil domain CCSMST1 PF15013.6 KZN89443.1 - 0.12 12.5 0.2 0.71 10.1 0.0 2.3 3 0 0 3 3 3 0 CCSMST1 family DHDPS PF00701.22 KZN89444.1 - 7.5e-38 129.9 0.0 8.9e-38 129.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PA PF02225.22 KZN89444.1 - 0.084 12.9 0.0 0.25 11.4 0.1 1.8 2 0 0 2 2 2 0 PA domain Ank_2 PF12796.7 KZN89445.1 - 2.5e-48 162.6 5.0 2.5e-11 44.0 0.0 6.6 4 2 0 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN89445.1 - 1.6e-36 124.2 0.8 2.2e-07 31.3 0.1 8.8 4 2 8 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN89445.1 - 1.8e-34 113.9 7.9 0.015 15.7 0.1 13.0 12 0 0 12 12 12 7 Ankyrin repeat Ank PF00023.30 KZN89445.1 - 5e-22 77.3 18.9 0.083 13.4 0.0 13.0 13 0 0 13 13 13 6 Ankyrin repeat Ank_5 PF13857.6 KZN89445.1 - 2.4e-15 56.4 9.5 0.096 13.0 0.0 9.8 4 3 7 11 11 11 3 Ankyrin repeats (many copies) NACHT PF05729.12 KZN89445.1 - 3.1e-11 43.5 0.1 8e-11 42.1 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KZN89445.1 - 1.2e-05 25.6 0.1 8.2e-05 22.9 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KZN89445.1 - 0.00015 22.2 0.3 0.00065 20.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain NACHT_N PF17100.5 KZN89445.1 - 0.036 13.9 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase KAP_NTPase PF07693.14 KZN89445.1 - 0.04 13.1 0.2 0.42 9.8 0.1 2.4 2 1 1 3 3 3 0 KAP family P-loop domain PIF1 PF05970.14 KZN89445.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Cyanate_lyase PF02560.14 KZN89446.1 - 1.4e-32 111.4 0.1 2.4e-32 110.6 0.0 1.4 2 0 0 2 2 2 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 KZN89446.1 - 0.0023 18.2 0.0 0.0036 17.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Homeodomain PF00046.29 KZN89446.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Homeodomain zf-C2H2 PF00096.26 KZN89447.1 - 7e-07 29.4 12.8 0.13 12.7 0.0 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KZN89447.1 - 8.4e-06 26.2 17.7 0.11 13.4 0.1 5.5 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KZN89447.1 - 0.013 15.5 8.5 0.8 9.8 0.0 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger DUF948 PF06103.11 KZN89447.1 - 0.041 14.1 5.1 5.3 7.4 1.0 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4187 PF13821.6 KZN89447.1 - 0.06 13.1 2.0 4.4 7.2 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) Laminin_I PF06008.14 KZN89447.1 - 0.075 12.7 0.1 0.25 11.0 0.1 1.8 1 1 1 2 2 2 0 Laminin Domain I Laminin_II PF06009.12 KZN89447.1 - 0.27 11.2 5.0 1 9.4 0.8 2.3 1 1 1 2 2 2 0 Laminin Domain II zf-C2H2_8 PF15909.5 KZN89447.1 - 1.8 8.9 11.0 2.8 8.3 2.4 2.9 2 1 1 3 3 3 0 C2H2-type zinc ribbon DUF1387 PF07139.11 KZN89447.1 - 1.9 8.1 6.9 2.9 7.5 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) zf-C2H2_2 PF12756.7 KZN89447.1 - 4.4 7.7 22.1 1.2 9.5 0.5 3.8 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) DNA_pol_B PF00136.21 KZN89451.1 - 2.9e-149 497.7 2.3 4.1e-149 497.2 2.3 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KZN89451.1 - 1.1e-79 268.0 0.0 2.2e-79 267.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KZN89451.1 - 3.1e-18 66.0 7.3 6.5e-18 65.0 7.3 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 KZN89451.1 - 0.0032 16.4 0.5 0.021 13.7 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 KZN89451.1 - 0.011 15.8 0.6 0.083 12.9 0.6 2.4 1 1 0 1 1 1 0 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 KZN89451.1 - 0.064 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB ETC_C1_NDUFA5 PF04716.14 KZN89451.1 - 0.088 12.6 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 ETC complex I subunit conserved region DUF2508 PF10704.9 KZN89451.1 - 1.9 8.7 5.2 2.6 8.3 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2508) Pkinase PF00069.25 KZN89452.1 - 9.4e-34 117.0 0.0 6.2e-19 68.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KZN89452.1 - 2.1e-16 60.0 0.0 7e-07 28.8 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Kdo PF06293.14 KZN89452.1 - 0.042 13.2 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KZN89452.1 - 0.064 12.0 0.9 0.2 10.4 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase FTA2 PF13095.6 KZN89452.1 - 0.15 11.7 0.0 15 5.1 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KZN89452.1 - 0.15 12.0 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Acyl-CoA_dh_1 PF00441.24 KZN89453.1 - 4.2e-29 101.7 0.4 6.1e-29 101.2 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KZN89453.1 - 1.4e-26 93.3 0.0 3.9e-26 91.9 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KZN89453.1 - 9.4e-25 86.7 0.1 1.6e-24 85.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KZN89453.1 - 0.00057 20.2 0.2 0.00097 19.4 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Glyco_hydro_125 PF06824.11 KZN89454.1 - 1.4e-179 597.4 0.1 1.6e-179 597.2 0.1 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) CDC27 PF09507.10 KZN89455.1 - 3e-104 349.8 24.2 3.4e-104 349.6 24.2 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 PBP1_TM PF14812.6 KZN89455.1 - 4.2 7.8 16.0 20 5.7 10.8 3.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-C3HC4_2 PF13923.6 KZN89456.1 - 3.6e-11 42.7 16.1 1.6e-10 40.7 12.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KZN89456.1 - 2.4e-08 33.7 16.6 1.5e-07 31.1 12.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KZN89456.1 - 5.5e-08 32.5 13.4 1.5e-07 31.1 9.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KZN89456.1 - 7.5e-08 32.3 15.2 9e-07 28.8 11.5 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KZN89456.1 - 5.1e-07 29.5 17.1 1.7e-06 27.9 12.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KZN89456.1 - 2.5e-06 27.7 15.8 3.5e-05 24.0 13.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.6 KZN89456.1 - 3.5e-06 26.8 5.4 3.5e-06 26.8 5.4 1.7 2 0 0 2 2 2 1 zf-RING of BARD1-type protein SAP PF02037.27 KZN89456.1 - 2.2e-05 24.1 0.0 5.7e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 SAP domain zf-C3HC4_4 PF15227.6 KZN89456.1 - 5.1e-05 23.3 12.8 5.1e-05 23.3 12.8 2.7 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KZN89456.1 - 0.00037 20.3 13.7 0.05 13.5 11.5 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 Mob_synth_C PF06463.13 KZN89456.1 - 0.00044 20.2 2.2 0.0011 18.9 2.2 1.7 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C zf-rbx1 PF12678.7 KZN89456.1 - 0.0011 19.2 7.4 0.0011 19.2 7.4 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KZN89456.1 - 0.002 18.2 6.3 0.0044 17.1 6.3 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 U-box PF04564.15 KZN89456.1 - 0.0066 16.6 0.0 0.029 14.5 0.0 2.1 2 0 0 2 2 2 1 U-box domain Ebola_NP PF05505.12 KZN89456.1 - 0.011 14.1 0.2 0.015 13.7 0.2 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein zf-RING_4 PF14570.6 KZN89456.1 - 0.02 14.7 12.6 0.1 12.4 9.8 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KZN89456.1 - 0.028 14.5 2.9 0.078 13.0 2.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Snf7 PF03357.21 KZN89457.1 - 1.1e-15 57.6 10.3 1.1e-15 57.6 10.3 1.7 1 1 1 2 2 2 1 Snf7 TssO PF17561.2 KZN89457.1 - 0.048 13.8 0.9 0.13 12.3 0.4 1.9 2 0 0 2 2 2 0 Type VI secretion system, TssO NPV_P10 PF05531.12 KZN89457.1 - 0.093 13.2 2.5 16 6.0 2.5 3.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein HSBP1 PF06825.12 KZN89457.1 - 0.2 11.5 2.1 9.5 6.2 0.0 3.5 3 0 0 3 3 3 0 Heat shock factor binding protein 1 BLOC1_2 PF10046.9 KZN89457.1 - 0.35 11.2 8.7 5 7.5 0.6 3.7 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 KZN89457.1 - 0.63 10.1 8.2 4 7.5 5.5 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FAM76 PF16046.5 KZN89457.1 - 3.7 6.8 8.1 0.33 10.3 1.7 2.1 2 0 0 2 2 2 0 FAM76 protein DUF5082 PF16888.5 KZN89457.1 - 9.6 6.5 14.6 0.98 9.7 2.6 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) TRAPPC-Trs85 PF12739.7 KZN89458.1 - 5.8e-112 374.6 0.0 8.8e-112 374.0 0.0 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit PolyA_pol PF01743.20 KZN89459.1 - 1.2e-21 77.4 1.6 9.4e-21 74.5 1.6 2.2 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KZN89459.1 - 7.6e-07 28.8 0.1 2e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 KZN89459.1 - 0.00042 20.3 0.1 0.0036 17.3 0.0 2.2 2 0 0 2 2 2 1 tRNA nucleotidyltransferase domain 2 putative Tti2 PF10521.9 KZN89460.1 - 1e-95 320.5 1.5 1.4e-95 320.1 1.5 1.2 1 0 0 1 1 1 1 Tti2 family SPATA9 PF15824.5 KZN89460.1 - 0.11 11.8 0.1 0.2 10.9 0.1 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 9 Syja_N PF02383.18 KZN89461.1 - 2.3e-81 273.6 0.0 3.9e-81 272.8 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain Ank_2 PF12796.7 KZN89462.1 - 5.2e-49 164.7 0.1 5.6e-15 55.7 0.0 5.6 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN89462.1 - 4.1e-34 116.5 0.1 4.8e-08 33.4 0.0 6.7 4 3 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN89462.1 - 5.5e-32 106.2 0.0 0.0002 21.5 0.0 10.1 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 KZN89462.1 - 4.7e-31 106.4 0.1 0.00025 21.3 0.0 8.4 1 1 8 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 KZN89462.1 - 1.2e-26 92.0 1.9 0.0056 17.1 0.0 9.7 9 0 0 9 9 9 7 Ankyrin repeat NACHT_N PF17100.5 KZN89462.1 - 1.9e-21 76.9 0.0 3.6e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 KZN89462.1 - 1e-06 28.8 0.5 5.4e-06 26.4 0.1 2.3 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KZN89462.1 - 0.00011 22.7 0.0 0.00029 21.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KZN89462.1 - 0.012 15.7 0.0 0.038 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KZN89462.1 - 0.047 13.4 0.0 0.68 9.6 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KZN89462.1 - 0.048 13.9 0.0 0.49 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain HNH_2 PF13391.6 KZN89463.1 - 1.1e-08 35.1 0.0 2.3e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Pex2_Pex12 PF04757.14 KZN89464.1 - 1.2e-55 188.5 1.6 1.6e-55 188.2 1.6 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 KZN89464.1 - 3.5e-05 23.9 2.3 6.4e-05 23.0 2.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KZN89464.1 - 0.0007 19.4 3.6 0.00091 19.0 2.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KZN89464.1 - 0.0045 16.8 1.9 0.0078 16.0 1.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KZN89464.1 - 0.0065 16.8 2.4 0.013 15.8 2.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KZN89464.1 - 0.021 14.7 1.6 0.037 13.9 1.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KZN89464.1 - 0.12 12.5 5.5 0.043 13.8 2.6 1.8 2 0 0 2 2 2 0 RING-type zinc-finger DUF4456 PF14644.6 KZN89464.1 - 0.19 11.4 0.6 0.3 10.7 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) RsfS PF02410.15 KZN89465.1 - 3e-12 46.8 0.0 6.5e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation PT-VENN PF04829.13 KZN89465.1 - 0.087 12.9 0.4 0.24 11.5 0.4 1.7 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif NMD3 PF04981.13 KZN89466.1 - 5.8e-77 258.4 6.7 5.8e-77 258.4 6.7 1.6 2 0 0 2 2 2 1 NMD3 family WRNPLPNID PF15017.6 KZN89466.1 - 0.26 12.2 0.0 0.26 12.2 0.0 3.2 2 1 0 2 2 2 0 Putative WW-binding domain and destruction box Mating_C PF12737.7 KZN89467.1 - 0.061 12.6 0.1 0.062 12.5 0.1 1.0 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 DUF2735 PF10931.8 KZN89468.1 - 2.9 8.6 4.7 1.9 9.2 0.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2735) DNA_pol_phi PF04931.13 KZN89468.1 - 9.9 4.1 13.1 16 3.5 13.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi Mito_carr PF00153.27 KZN89469.1 - 2.7e-62 206.7 1.5 3.2e-22 78.2 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KZN89469.1 - 0.062 12.4 0.0 7.2 5.7 0.0 2.4 2 0 0 2 2 2 0 Gammaproteobacterial serine protease WAC_Acf1_DNA_bd PF10537.9 KZN89470.1 - 1.7e-39 134.4 0.2 1.7e-39 134.4 0.2 2.8 3 0 0 3 3 3 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 KZN89470.1 - 9.6e-23 80.5 4.7 1.1e-22 80.3 0.6 3.1 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KZN89470.1 - 2.9e-17 62.7 2.2 6.3e-17 61.6 2.2 1.6 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 KZN89470.1 - 4.1e-06 26.2 0.1 9.8e-06 25.0 0.1 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Alg6_Alg8 PF03155.15 KZN89471.1 - 3.6e-174 580.3 30.2 4.7e-174 579.9 30.2 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Lectin_leg-like PF03388.13 KZN89472.1 - 2.5e-28 99.0 0.0 3.7e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Nup54 PF13874.6 KZN89472.1 - 0.061 13.4 2.7 0.092 12.9 2.7 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Peptidase_M32 PF02074.15 KZN89472.1 - 0.066 12.0 0.4 0.091 11.5 0.4 1.1 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase Bac_luciferase PF00296.20 KZN89472.1 - 0.16 11.3 0.0 12 5.2 0.0 2.1 1 1 1 2 2 2 0 Luciferase-like monooxygenase ABC_tran_CTD PF16326.5 KZN89472.1 - 0.21 11.8 3.2 1.1 9.6 0.1 2.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF4140 PF13600.6 KZN89472.1 - 0.24 11.9 1.3 0.43 11.1 1.3 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF5385 PF17359.2 KZN89472.1 - 3.6 7.1 5.7 0.42 10.1 0.9 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5385) PHD PF00628.29 KZN89473.1 - 3.5e-17 62.0 24.5 2.4e-10 40.2 10.5 2.5 2 0 0 2 2 2 2 PHD-finger zf-RanBP PF00641.18 KZN89473.1 - 0.031 13.6 0.2 0.031 13.6 0.2 2.5 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others C1_1 PF00130.22 KZN89473.1 - 0.23 11.4 15.6 0.24 11.3 3.6 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 KZN89473.1 - 0.53 9.9 15.6 0.2 11.2 0.3 3.4 3 0 0 3 3 3 0 PHD-finger zf-PHD-like PF15446.6 KZN89473.1 - 7.9 6.1 13.5 4.4 6.9 3.2 2.9 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Peptidase_M24 PF00557.24 KZN89474.1 - 3.8e-07 30.0 0.0 5.4e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 NusA_N PF08529.11 KZN89474.1 - 0.38 11.1 3.4 7.3 7.0 1.0 2.6 2 0 0 2 2 2 0 NusA N-terminal domain Exo_endo_phos PF03372.23 KZN89475.1 - 7.8e-09 35.4 0.1 2.8e-08 33.6 0.1 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SNF5 PF04855.12 KZN89476.1 - 1.6e-63 214.7 0.7 1.6e-62 211.4 0.7 2.1 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 HEAT_2 PF13646.6 KZN89477.1 - 3.1e-07 30.7 3.9 0.0021 18.4 0.0 4.5 5 0 0 5 5 5 2 HEAT repeats Cnd1 PF12717.7 KZN89477.1 - 0.0002 21.5 2.4 1.1 9.2 0.0 4.5 5 1 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KZN89477.1 - 0.00024 21.1 8.3 0.076 13.3 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 KZN89477.1 - 0.0037 17.7 3.1 0.2 12.2 0.1 4.5 4 0 0 4 4 4 1 HEAT-like repeat Nipped-B_C PF12830.7 KZN89477.1 - 0.041 13.8 0.1 0.83 9.6 0.0 2.8 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus XPC-binding PF09280.11 KZN89477.1 - 0.35 10.6 3.2 3.9 7.3 0.6 2.8 2 0 0 2 2 2 0 XPC-binding domain Adaptin_N PF01602.20 KZN89477.1 - 0.36 9.3 3.2 1 7.8 0.1 3.0 4 1 0 4 4 4 0 Adaptin N terminal region RIX1 PF08167.12 KZN89477.1 - 0.67 9.7 3.8 3.3 7.4 0.0 3.8 5 0 0 5 5 5 0 rRNA processing/ribosome biogenesis MFS_1 PF07690.16 KZN89478.1 - 2.9e-39 135.0 42.4 2.9e-39 135.0 42.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3464 PF11947.8 KZN89478.1 - 0.023 14.4 6.5 0.64 9.8 0.0 3.6 4 0 0 4 4 4 0 Photosynthesis affected mutant 68 OATP PF03137.20 KZN89478.1 - 0.099 10.9 5.5 0.85 7.8 6.3 2.1 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family AAA PF00004.29 KZN89479.1 - 2.5e-97 322.4 0.0 3.6e-47 160.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KZN89479.1 - 3.3e-22 78.0 6.2 2.1e-12 46.6 1.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 KZN89479.1 - 3.3e-19 68.8 0.9 9.6e-19 67.4 0.4 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KZN89479.1 - 1.2e-14 54.4 0.0 6.5e-06 26.0 0.0 3.8 4 1 0 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KZN89479.1 - 2.5e-14 53.7 0.0 1e-07 32.2 0.0 3.0 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KZN89479.1 - 1.1e-12 48.3 0.0 1.7e-05 25.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KZN89479.1 - 1.6e-12 48.1 0.0 0.00021 21.7 0.0 4.8 3 2 1 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 KZN89479.1 - 2.3e-11 43.9 0.6 2e-05 24.6 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.17 KZN89479.1 - 1.9e-09 37.1 0.0 4.1e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 KZN89479.1 - 2.9e-09 37.3 0.4 0.032 14.5 0.0 4.3 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.13 KZN89479.1 - 3.2e-09 36.5 0.1 0.0016 17.7 0.0 2.7 2 1 0 2 2 2 2 TIP49 P-loop domain Mg_chelatase PF01078.21 KZN89479.1 - 1.4e-07 31.1 0.6 0.011 15.2 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Vps4_C PF09336.10 KZN89479.1 - 5e-07 29.6 0.1 1.6e-05 24.8 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_14 PF13173.6 KZN89479.1 - 5.4e-07 29.7 0.0 0.016 15.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.17 KZN89479.1 - 5.4e-07 29.5 0.0 0.019 14.7 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 KZN89479.1 - 6e-07 29.8 0.0 0.029 14.7 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 KZN89479.1 - 7.4e-07 29.8 0.0 0.029 14.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KZN89479.1 - 1.1e-06 28.4 3.5 0.35 10.4 0.1 4.6 3 2 1 5 5 5 2 AAA domain ATPase PF06745.13 KZN89479.1 - 1.9e-06 27.4 0.4 0.51 9.6 0.0 3.4 3 0 0 3 3 3 2 KaiC AAA_7 PF12775.7 KZN89479.1 - 5.5e-06 26.0 0.1 0.042 13.3 0.0 3.2 2 2 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 KZN89479.1 - 9.1e-06 25.5 0.0 0.13 11.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 KZN89479.1 - 1.5e-05 24.2 0.1 0.052 12.6 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.13 KZN89479.1 - 2e-05 23.9 0.0 0.015 14.5 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 KZN89479.1 - 2.4e-05 24.7 0.0 0.18 12.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 KZN89479.1 - 3.6e-05 23.5 0.1 0.43 10.3 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain Bac_DnaA PF00308.18 KZN89479.1 - 4.7e-05 23.3 0.0 0.27 11.1 0.0 3.2 4 0 0 4 4 3 2 Bacterial dnaA protein ABC_tran PF00005.27 KZN89479.1 - 0.00015 22.3 0.0 0.56 10.7 0.0 3.5 2 1 0 2 2 2 1 ABC transporter TsaE PF02367.17 KZN89479.1 - 0.00015 21.7 0.0 0.33 10.9 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 KZN89479.1 - 0.00016 22.1 0.0 0.6 10.5 0.0 3.2 3 0 0 3 3 2 1 AAA domain ResIII PF04851.15 KZN89479.1 - 0.00023 21.2 0.0 0.078 13.0 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KZN89479.1 - 0.00027 20.5 0.4 0.7 9.3 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein NACHT PF05729.12 KZN89479.1 - 0.00032 20.7 0.1 0.18 11.7 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_11 PF13086.6 KZN89479.1 - 0.00034 20.5 0.1 1.1 9.0 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_3 PF07726.11 KZN89479.1 - 0.00037 20.3 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KZN89479.1 - 0.00049 19.9 0.2 0.56 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KZN89479.1 - 0.00061 19.8 0.0 2.3 8.1 0.0 3.6 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea DUF2075 PF09848.9 KZN89479.1 - 0.0018 17.6 0.0 1.4 8.1 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 KZN89479.1 - 0.0039 17.0 0.0 0.35 10.6 0.0 2.6 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KZN89479.1 - 0.0055 17.1 0.8 5.7 7.3 0.0 3.4 3 1 0 4 4 2 0 AAA domain NTPase_1 PF03266.15 KZN89479.1 - 0.0072 16.3 0.7 2.5 8.0 0.0 4.1 4 0 0 4 4 3 1 NTPase NB-ARC PF00931.22 KZN89479.1 - 0.0086 15.3 0.0 1.7 7.7 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain Zeta_toxin PF06414.12 KZN89479.1 - 0.01 15.1 0.0 6.1 6.1 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin KAP_NTPase PF07693.14 KZN89479.1 - 0.011 15.1 0.2 0.93 8.7 0.0 3.0 2 2 0 3 3 3 0 KAP family P-loop domain IPT PF01745.16 KZN89479.1 - 0.017 14.5 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Sigma54_activ_2 PF14532.6 KZN89479.1 - 0.027 14.6 0.0 3.8 7.6 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Zot PF05707.12 KZN89479.1 - 0.039 13.6 0.0 2 8.0 0.0 3.1 3 1 0 3 3 2 0 Zonular occludens toxin (Zot) UFD1 PF03152.14 KZN89479.1 - 0.044 13.3 0.0 0.41 10.1 0.0 2.1 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 Cytidylate_kin PF02224.18 KZN89479.1 - 0.053 13.2 0.0 10 5.8 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase AFG1_ATPase PF03969.16 KZN89479.1 - 0.065 12.1 0.0 8.7 5.1 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase AAA_6 PF12774.7 KZN89479.1 - 0.068 12.1 0.2 9.1 5.1 0.0 2.5 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region PEX11 PF05648.14 KZN89480.1 - 5.4e-13 48.9 0.0 8.9e-11 41.7 0.0 2.1 1 1 1 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Mpv17_PMP22 PF04117.12 KZN89482.1 - 1.3e-12 47.8 1.1 1.7e-11 44.2 0.9 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family Cullin_binding PF03556.15 KZN89483.1 - 4.3e-32 111.1 1.7 7.9e-32 110.2 1.7 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 KZN89483.1 - 6.7e-09 35.4 0.0 1.4e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UPF0113_N PF17833.1 KZN89484.1 - 1.1e-25 90.0 0.0 1.5e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 KZN89484.1 - 4.8e-22 78.0 0.0 7.1e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain PUA PF01472.20 KZN89484.1 - 1.7e-06 27.9 0.0 2.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 PUA domain NOC3p PF07540.11 KZN89485.1 - 2.6e-31 107.9 0.3 1.2e-30 105.8 0.3 2.2 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 KZN89485.1 - 5.5e-26 91.6 2.4 1.5e-25 90.2 0.2 2.5 2 0 0 2 2 2 1 CBF/Mak21 family SLX9 PF15341.6 KZN89485.1 - 0.054 13.9 7.2 0.062 13.7 3.7 2.6 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 GAS PF13851.6 KZN89486.1 - 0.0005 19.5 4.1 0.0005 19.5 4.1 1.9 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding DUF3584 PF12128.8 KZN89486.1 - 0.00079 17.1 5.6 0.0011 16.6 5.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) WEMBL PF05701.11 KZN89486.1 - 0.0011 17.7 6.0 0.0018 17.1 6.0 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Spc7 PF08317.11 KZN89486.1 - 0.0013 17.7 7.9 0.0013 17.7 7.9 1.5 1 1 0 1 1 1 1 Spc7 kinetochore protein DUF4763 PF15960.5 KZN89486.1 - 0.0075 15.6 1.1 0.0075 15.6 1.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4763) IFT57 PF10498.9 KZN89486.1 - 0.013 14.5 3.7 0.027 13.5 3.7 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Fib_alpha PF08702.10 KZN89486.1 - 0.016 15.4 6.3 0.042 14.1 2.5 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family HAP1_N PF04849.13 KZN89486.1 - 0.017 14.4 5.7 0.036 13.3 5.6 1.5 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Cep57_MT_bd PF06657.13 KZN89486.1 - 0.023 15.1 2.0 1.1 9.7 0.3 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF1664 PF07889.12 KZN89486.1 - 0.028 14.4 8.5 0.11 12.5 4.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 KZN89486.1 - 0.028 14.4 8.3 0.082 12.9 8.3 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.11 KZN89486.1 - 0.032 14.5 1.5 0.087 13.1 0.5 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Prominin PF05478.11 KZN89486.1 - 0.042 11.8 1.1 0.058 11.4 1.1 1.1 1 0 0 1 1 1 0 Prominin CREPT PF16566.5 KZN89486.1 - 0.044 13.9 3.7 0.1 12.8 3.7 1.6 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour DUF677 PF05055.12 KZN89486.1 - 0.047 12.6 1.9 0.054 12.4 0.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF677) Filament PF00038.21 KZN89486.1 - 0.048 13.2 10.0 0.084 12.4 10.0 1.4 1 0 0 1 1 1 0 Intermediate filament protein DUF5082 PF16888.5 KZN89486.1 - 0.049 13.9 5.6 0.88 9.9 4.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Sec2p PF06428.11 KZN89486.1 - 0.049 13.6 5.2 6.2 6.9 3.0 2.5 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Laminin_II PF06009.12 KZN89486.1 - 0.051 13.6 4.5 0.061 13.3 0.8 2.4 1 1 2 3 3 3 0 Laminin Domain II NPV_P10 PF05531.12 KZN89486.1 - 0.052 14.0 4.6 0.19 12.2 0.3 3.0 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein MspA PF09203.11 KZN89486.1 - 0.056 13.3 1.1 0.12 12.3 1.1 1.5 1 0 0 1 1 1 0 MspA AAA_23 PF13476.6 KZN89486.1 - 0.063 13.8 2.3 0.12 12.9 2.3 1.5 1 0 0 1 1 1 0 AAA domain Tektin PF03148.14 KZN89486.1 - 0.066 11.9 9.1 0.12 11.1 8.0 1.9 1 1 0 1 1 1 0 Tektin family MIP-T3_C PF17749.1 KZN89486.1 - 0.067 13.2 6.6 0.055 13.4 1.8 2.5 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region THOC7 PF05615.13 KZN89486.1 - 0.069 13.4 10.2 0.07 13.4 6.5 2.2 2 0 0 2 2 2 0 Tho complex subunit 7 YgaB PF14182.6 KZN89486.1 - 0.079 13.4 1.2 2.6 8.5 2.6 2.6 2 0 0 2 2 2 0 YgaB-like protein Seryl_tRNA_N PF02403.22 KZN89486.1 - 0.086 13.1 10.0 0.028 14.7 6.6 2.0 2 1 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain V-SNARE PF05008.15 KZN89486.1 - 0.091 13.1 2.9 0.37 11.2 2.9 2.0 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus V_ATPase_I PF01496.19 KZN89486.1 - 0.095 10.6 6.5 0.15 10.0 6.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FapA PF03961.13 KZN89486.1 - 0.12 10.9 2.7 0.18 10.4 2.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Sec8_exocyst PF04048.14 KZN89486.1 - 0.14 12.0 0.6 0.28 11.1 0.6 1.4 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain TPR_MLP1_2 PF07926.12 KZN89486.1 - 0.15 12.1 11.4 2.4 8.2 8.3 3.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.12 KZN89486.1 - 0.19 11.8 0.5 0.81 9.7 0.5 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus bZIP_1 PF00170.21 KZN89486.1 - 0.19 11.8 2.8 1.3 9.2 1.5 2.5 2 0 0 2 2 2 0 bZIP transcription factor AAA_13 PF13166.6 KZN89486.1 - 0.22 10.1 7.7 0.16 10.6 6.1 1.4 1 1 0 1 1 1 0 AAA domain DUF4618 PF15397.6 KZN89486.1 - 0.25 10.7 10.0 0.14 11.5 5.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) PEARLI-4 PF05278.12 KZN89486.1 - 0.31 10.6 5.3 0.53 9.8 5.3 1.3 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) YvrJ PF12841.7 KZN89486.1 - 0.44 10.1 1.0 21 4.7 0.1 2.3 2 0 0 2 2 2 0 YvrJ protein family DUF641 PF04859.12 KZN89486.1 - 0.5 10.7 6.9 0.31 11.4 3.7 2.3 2 1 0 2 2 1 0 Plant protein of unknown function (DUF641) SKA2 PF16740.5 KZN89486.1 - 0.6 9.9 7.2 0.23 11.3 3.1 2.3 2 1 1 3 3 2 0 Spindle and kinetochore-associated protein 2 DUF2203 PF09969.9 KZN89486.1 - 0.64 10.8 4.8 0.85 10.4 3.4 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF2353 PF09789.9 KZN89486.1 - 0.64 9.3 13.1 0.73 9.1 5.3 2.3 1 1 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) GreA_GreB_N PF03449.15 KZN89486.1 - 0.72 10.0 6.4 0.42 10.8 1.6 2.8 2 1 1 3 3 2 0 Transcription elongation factor, N-terminal Wtap PF17098.5 KZN89486.1 - 0.78 9.7 5.7 0.45 10.4 3.3 1.9 2 0 0 2 2 1 0 WTAP/Mum2p family Atg14 PF10186.9 KZN89486.1 - 0.8 8.7 8.1 0.056 12.5 2.8 1.8 2 0 0 2 2 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 USP8_interact PF08941.10 KZN89486.1 - 0.82 9.5 4.6 9.5 6.0 0.4 2.3 1 1 1 2 2 2 0 USP8 interacting TMF_DNA_bd PF12329.8 KZN89486.1 - 0.85 9.7 9.3 7.8 6.6 3.1 3.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF2730 PF10805.8 KZN89486.1 - 0.95 9.6 4.7 0.56 10.3 1.6 2.2 2 1 0 2 2 1 0 Protein of unknown function (DUF2730) TMPIT PF07851.13 KZN89486.1 - 1.1 8.5 5.7 1.1 8.4 2.6 1.9 1 1 1 2 2 2 0 TMPIT-like protein Fzo_mitofusin PF04799.13 KZN89486.1 - 1.3 8.6 4.0 20 4.7 0.1 2.4 1 1 1 2 2 2 0 fzo-like conserved region COMP PF11598.8 KZN89486.1 - 1.4 9.5 2.9 0.86 10.1 0.5 1.9 2 0 0 2 2 1 0 Cartilage oligomeric matrix protein FlaC_arch PF05377.11 KZN89486.1 - 1.4 9.3 6.3 0.59 10.6 0.7 3.1 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) BST2 PF16716.5 KZN89486.1 - 1.5 9.4 9.5 0.054 14.1 2.1 2.3 3 0 0 3 3 1 0 Bone marrow stromal antigen 2 DivIC PF04977.15 KZN89486.1 - 1.7 8.5 9.3 0.073 12.8 1.5 2.7 3 1 0 3 3 2 0 Septum formation initiator ARGLU PF15346.6 KZN89486.1 - 1.8 8.4 12.5 5.2 6.9 12.5 1.7 1 1 0 1 1 1 0 Arginine and glutamate-rich 1 Syntaxin_2 PF14523.6 KZN89486.1 - 2 8.9 5.4 3.1 8.2 2.8 2.6 1 1 1 2 2 2 0 Syntaxin-like protein ZapB PF06005.12 KZN89486.1 - 2 8.9 11.9 1.7 9.1 4.6 3.1 3 0 0 3 3 2 0 Cell division protein ZapB Mod_r PF07200.13 KZN89486.1 - 2 8.5 7.5 2.9 8.0 6.2 1.8 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Tup_N PF08581.10 KZN89486.1 - 2.3 8.6 12.9 3.8 7.9 0.1 3.3 3 0 0 3 3 3 0 Tup N-terminal UPF0242 PF06785.11 KZN89486.1 - 2.8 8.0 13.3 0.64 10.1 8.7 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 KZN89486.1 - 2.9 8.6 7.8 6 7.6 3.6 2.7 1 1 2 3 3 2 0 Initiation control protein YabA BLOC1_2 PF10046.9 KZN89486.1 - 3.3 8.1 9.0 0.64 10.3 2.7 2.5 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF724 PF05266.14 KZN89486.1 - 6 6.6 8.4 17 5.2 8.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Cnn_1N PF07989.11 KZN89486.1 - 7.9 6.7 9.7 1.2 9.3 5.2 2.1 2 1 0 2 2 1 0 Centrosomin N-terminal motif 1 DUF4407 PF14362.6 KZN89486.1 - 8.8 5.6 9.0 0.17 11.2 2.2 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4407) Sulfate_transp PF00916.20 KZN89488.1 - 1.8e-112 375.9 18.2 2.5e-112 375.4 18.2 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KZN89488.1 - 6.1e-09 35.5 0.0 1.7e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 STAS domain SNN_transmemb PF09049.10 KZN89488.1 - 0.003 17.4 2.0 0.003 17.4 2.0 3.9 5 0 0 5 5 5 1 Stannin transmembrane MFS_MOT1 PF16983.5 KZN89488.1 - 6 7.3 22.0 0.022 15.2 3.4 3.4 3 1 0 3 3 3 0 Molybdate transporter of MFS superfamily ATP-synt_C PF00137.21 KZN89489.1 - 6.8e-09 35.9 13.6 1.3e-08 35.1 13.6 1.5 1 0 0 1 1 1 1 ATP synthase subunit C FIN1 PF17300.2 KZN89489.1 - 0.018 14.5 0.1 0.021 14.3 0.1 1.1 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 DUF1349 PF07081.11 KZN89490.1 - 1.9e-23 83.1 0.0 2.3e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) TNFR_16_TM PF18422.1 KZN89491.1 - 0.61 10.1 4.1 0.76 9.8 0.5 3.0 3 0 0 3 3 3 0 Tumor necrosis factor receptor member 16 trans-membrane domain Cript PF10235.9 KZN89492.1 - 1.9e-25 89.2 8.2 1.9e-25 89.2 8.2 1.7 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.7 KZN89492.1 - 0.0046 16.9 14.8 0.035 14.1 8.7 2.6 1 1 1 2 2 2 2 Double zinc ribbon zinc_ribbon_15 PF17032.5 KZN89492.1 - 0.0073 17.0 10.8 0.0097 16.6 7.2 2.5 2 1 0 2 2 2 1 zinc-ribbon family CEBP_ZZ PF16366.5 KZN89492.1 - 0.041 14.1 4.1 0.041 14.1 4.1 1.9 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain NinF PF05810.12 KZN89492.1 - 0.48 10.3 5.7 6.4 6.7 0.0 2.9 2 1 1 3 3 3 0 NinF protein zinc_ribbon_2 PF13240.6 KZN89492.1 - 1.3 8.9 14.2 7.5 6.4 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Prim_Zn_Ribbon PF08273.12 KZN89492.1 - 5.6 7.3 11.7 37 4.7 0.0 4.0 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase DUF2039 PF10217.9 KZN89492.1 - 6.4 7.2 18.5 2.5 8.5 12.1 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) MRP-L46 PF11788.8 KZN89493.1 - 3e-38 131.2 1.3 5.7e-38 130.3 1.3 1.5 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 KZN89493.1 - 0.0014 18.7 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain CAF1 PF04857.20 KZN89494.1 - 1.4e-77 261.0 0.0 1.7e-77 260.7 0.0 1.0 1 0 0 1 1 1 1 CAF1 family ribonuclease Macoilin PF09726.9 KZN89495.1 - 0.012 14.2 0.9 0.016 13.8 0.9 1.1 1 0 0 1 1 1 0 Macoilin family ATP1G1_PLM_MAT8 PF02038.16 KZN89495.1 - 0.19 11.2 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family SBF_like PF13593.6 KZN89496.1 - 1.4e-92 310.3 16.4 1.6e-92 310.1 16.4 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Mito_carr PF00153.27 KZN89497.1 - 1.2e-65 217.4 3.3 1.7e-22 79.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cofilin_ADF PF00241.20 KZN89498.1 - 8.3e-25 86.9 0.0 1.6e-13 50.5 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Pinin_SDK_memA PF04696.13 KZN89499.1 - 9.7e-32 109.8 11.0 9.7e-32 109.8 11.0 2.8 3 0 0 3 3 3 1 pinin/SDK/memA/ protein conserved region RSB_motif PF16294.5 KZN89499.1 - 0.0068 16.7 9.1 0.0068 16.7 9.1 3.9 3 2 1 4 4 4 1 RNSP1-SAP18 binding (RSB) motif PHF5 PF03660.14 KZN89500.1 - 8.2e-53 177.0 9.7 9.1e-53 176.9 9.7 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 KZN89500.1 - 0.13 10.2 5.2 0.13 10.1 5.2 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 KZN89500.1 - 2 8.5 15.5 5.7 7.0 2.0 3.0 1 1 1 2 2 2 0 Double zinc ribbon Abhydrolase_1 PF00561.20 KZN89501.1 - 3.9e-16 59.5 0.3 7.4e-08 32.3 0.1 3.0 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KZN89501.1 - 1.8e-11 45.1 0.3 3.8e-11 44.0 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KZN89501.1 - 6.1e-09 35.5 0.0 4e-05 23.0 0.0 3.0 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KZN89501.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Sacchrp_dh_NADP PF03435.18 KZN89502.1 - 1.3e-17 64.3 0.0 2e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Ribosomal_L37ae PF01780.19 KZN89503.1 - 7.4e-41 138.1 10.2 8.3e-41 138.0 10.2 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 KZN89503.1 - 0.00041 20.4 1.9 0.00058 19.9 1.9 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF1451 PF07295.11 KZN89503.1 - 0.0048 16.9 0.8 0.0067 16.5 0.8 1.2 1 0 0 1 1 1 1 Zinc-ribbon containing domain A2L_zn_ribbon PF08792.10 KZN89503.1 - 0.011 15.4 2.1 0.7 9.7 0.0 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 KZN89503.1 - 0.014 15.4 1.9 0.024 14.6 1.9 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-BED PF02892.15 KZN89503.1 - 0.078 13.0 3.8 0.8 9.8 0.4 2.2 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 KZN89503.1 - 0.12 12.8 4.1 2 9.0 0.6 2.3 1 1 1 2 2 2 0 Zinc-finger double domain C1_2 PF03107.16 KZN89503.1 - 0.26 11.6 1.9 2.4 8.5 2.0 2.0 1 1 1 2 2 2 0 C1 domain zf-C2H2 PF00096.26 KZN89503.1 - 0.96 10.0 3.9 16 6.2 0.5 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type PHD PF00628.29 KZN89504.1 - 5e-10 39.1 13.1 7.3e-10 38.6 4.7 2.6 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 KZN89504.1 - 1.2e-08 35.1 4.2 1.2e-08 35.1 4.2 3.2 2 1 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KZN89504.1 - 1.1e-06 28.8 0.6 1.1e-06 28.8 0.6 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KZN89504.1 - 1.3e-06 28.2 0.9 1.3e-06 28.2 0.9 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KZN89504.1 - 4.3e-06 26.5 0.6 4.3e-06 26.5 0.6 2.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KZN89504.1 - 4.8e-06 26.4 0.5 4.8e-06 26.4 0.5 2.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KZN89504.1 - 2.3e-05 24.1 1.8 2.3e-05 24.1 1.8 2.5 4 0 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KZN89504.1 - 7e-05 22.6 0.9 7e-05 22.6 0.9 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.6 KZN89504.1 - 0.00035 20.1 1.8 0.00035 20.1 1.8 1.9 2 0 0 2 2 2 1 PHD-finger zf-ANAPC11 PF12861.7 KZN89504.1 - 0.00069 19.6 0.2 0.0019 18.2 0.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KZN89504.1 - 0.0014 18.6 0.9 0.0014 18.6 0.9 3.3 3 1 1 4 4 2 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KZN89504.1 - 0.0053 16.3 0.6 0.0053 16.3 0.6 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Rtf2 PF04641.12 KZN89504.1 - 0.022 14.1 0.0 0.022 14.1 0.0 2.8 4 0 0 4 4 4 0 Rtf2 RING-finger UvrA_inter PF17760.1 KZN89504.1 - 0.032 14.3 0.9 0.058 13.5 0.9 1.3 1 0 0 1 1 1 0 UvrA interaction domain zf-C2HC_2 PF13913.6 KZN89504.1 - 0.049 13.6 2.2 0.36 10.8 0.2 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-RING_11 PF17123.5 KZN89504.1 - 0.079 12.7 0.0 0.079 12.7 0.0 3.3 4 0 0 4 4 4 0 RING-like zinc finger Prok-RING_1 PF14446.6 KZN89504.1 - 0.7 9.9 9.1 0.26 11.2 1.3 3.0 4 0 0 4 4 3 0 Prokaryotic RING finger family 1 DZR PF12773.7 KZN89504.1 - 1.5 8.9 6.9 37 4.4 2.5 3.0 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.6 KZN89504.1 - 2.5 8.0 5.0 0.62 9.9 0.3 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-PHD-like PF15446.6 KZN89504.1 - 6.3 6.4 6.4 0.69 9.5 0.4 2.5 2 1 1 3 3 3 0 PHD/FYVE-zinc-finger like domain FMO-like PF00743.19 KZN89505.1 - 1e-17 63.8 0.0 4.2e-17 61.8 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KZN89505.1 - 1.6e-14 53.9 0.0 1.5e-13 50.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KZN89505.1 - 7.2e-12 45.1 0.1 4.6e-09 35.9 0.1 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KZN89505.1 - 1.7e-10 40.7 0.0 1.7e-08 34.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN89505.1 - 4.7e-09 36.3 0.0 3.9e-07 30.2 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KZN89505.1 - 3.2e-05 23.7 2.4 0.12 12.0 0.8 2.5 1 1 1 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 KZN89505.1 - 0.0006 19.1 0.0 0.073 12.3 0.0 2.6 3 0 0 3 3 3 1 Thi4 family Pyr_redox PF00070.27 KZN89505.1 - 0.0013 19.3 0.3 2 9.0 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KZN89505.1 - 0.0021 17.2 0.0 0.0042 16.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KZN89505.1 - 0.011 15.8 0.2 35 4.4 0.7 3.8 3 1 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KZN89505.1 - 0.023 13.4 0.5 0.23 10.1 0.2 2.3 2 0 0 2 2 2 0 HI0933-like protein Shikimate_DH PF01488.20 KZN89505.1 - 0.024 14.7 0.0 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 KZN89505.1 - 0.045 13.1 0.1 0.11 11.9 0.1 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KZN89505.1 - 0.17 11.3 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KZN89505.1 - 0.19 12.2 0.0 0.98 9.9 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding Fungal_trans PF04082.18 KZN89506.1 - 8.3e-16 57.8 0.7 1.4e-15 57.1 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1924 PF09086.11 KZN89506.1 - 0.053 13.9 1.2 0.13 12.6 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1924) ADH_zinc_N PF00107.26 KZN89507.1 - 1.4e-17 63.9 0.1 2.3e-17 63.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KZN89507.1 - 2.6e-10 40.1 0.1 1.4e-07 31.4 0.1 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KZN89507.1 - 2.2e-07 32.0 0.0 3.9e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KZN89507.1 - 0.043 13.1 0.5 0.057 12.7 0.5 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CpcD PF01383.21 KZN89507.1 - 0.05 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 CpcD/allophycocyanin linker domain NAD_binding_2 PF03446.15 KZN89507.1 - 0.1 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short_C2 PF13561.6 KZN89508.1 - 1.3e-57 195.1 0.3 1.5e-57 194.9 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN89508.1 - 2.3e-47 161.0 1.0 3e-47 160.6 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Abhydrolase_3 PF07859.13 KZN89509.1 - 3.1e-43 148.1 0.0 4.2e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KZN89509.1 - 1.7e-09 37.1 1.6 9.3e-09 34.7 1.6 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KZN89509.1 - 7.9e-06 26.6 1.1 1.4e-05 25.8 1.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KZN89509.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family EnY2 PF10163.9 KZN89510.1 - 1.9e-05 24.9 0.0 3.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Transcription factor e(y)2 SAM_2 PF07647.17 KZN89511.1 - 1.8e-14 53.6 0.0 3.6e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 KZN89511.1 - 2.2e-13 50.6 0.0 4.3e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.30 KZN89511.1 - 3.1e-13 50.0 0.0 5.4e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_4 PF18017.1 KZN89511.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Fungal_trans PF04082.18 KZN89512.1 - 3.6e-22 78.7 0.1 7.8e-22 77.6 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain ADH_N PF08240.12 KZN89513.1 - 7.5e-31 106.2 0.6 1.3e-30 105.5 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN89513.1 - 4e-22 78.6 0.3 6.2e-22 78.0 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KZN89513.1 - 6.2e-10 38.9 0.0 1.1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KZN89513.1 - 6.2e-05 24.1 0.0 0.00015 22.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KZN89513.1 - 0.0015 17.9 0.5 0.0028 17.0 0.5 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KZN89513.1 - 0.0057 15.9 0.0 0.0092 15.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KZN89513.1 - 0.032 13.8 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KZN89513.1 - 0.033 13.5 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sugar_tr PF00083.24 KZN89514.1 - 3.5e-95 319.5 25.8 4.1e-95 319.3 25.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN89514.1 - 5.7e-37 127.5 44.3 1.4e-31 109.7 23.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SPT_ssu-like PF11779.8 KZN89514.1 - 0.01 15.5 2.2 0.034 13.8 2.2 1.9 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like TRI12 PF06609.13 KZN89514.1 - 0.034 12.6 8.3 0.4 9.0 3.2 2.3 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Polysacc_deac_1 PF01522.21 KZN89516.1 - 3.7e-31 107.6 0.0 6.7e-31 106.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 KZN89516.1 - 3.9e-05 24.0 51.0 5e-05 23.7 14.8 3.0 3 1 1 4 4 4 2 Chitin recognition protein Glyco_hydro_57 PF03065.15 KZN89516.1 - 0.21 10.8 0.0 0.37 10.0 0.0 1.4 1 1 0 1 1 1 0 Glycosyl hydrolase family 57 HEAT_2 PF13646.6 KZN89517.1 - 0.0017 18.7 0.8 0.025 15.0 0.3 3.0 3 1 0 3 3 3 1 HEAT repeats Adaptin_N PF01602.20 KZN89517.1 - 0.003 16.2 0.3 0.3 9.6 0.1 2.7 2 1 1 3 3 3 1 Adaptin N terminal region Cnd3 PF12719.7 KZN89517.1 - 0.0038 16.5 0.1 0.0082 15.4 0.0 1.6 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 KZN89517.1 - 0.0058 16.8 0.4 1.5 9.3 0.0 3.6 4 0 0 4 4 4 1 HEAT repeat RTP1_C1 PF10363.9 KZN89517.1 - 0.0083 16.3 0.1 0.02 15.0 0.1 1.6 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 KZN89517.1 - 0.0085 16.7 0.0 0.025 15.2 0.0 1.8 1 0 0 1 1 1 1 Vacuolar 14 Fab1-binding region UME PF08064.13 KZN89517.1 - 0.01 15.8 0.5 4.2 7.3 0.0 2.9 2 1 1 3 3 3 0 UME (NUC010) domain DRIM PF07539.12 KZN89517.1 - 0.053 11.8 2.1 1.7 6.9 0.2 2.1 1 1 1 2 2 2 0 Down-regulated in metastasis DUF4072 PF13284.6 KZN89517.1 - 0.077 13.4 0.0 0.22 12.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4072) PRRSV_Env PF02340.15 KZN89517.1 - 0.098 12.0 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 PRRSV putative envelope protein Mitofilin PF09731.9 KZN89518.1 - 0.23 10.2 25.6 0.3 9.9 25.6 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein VIR_N PF15912.5 KZN89518.1 - 5.7 6.5 24.3 6.7 6.2 24.3 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Presenilin PF01080.17 KZN89518.1 - 8.3 5.1 24.0 12 4.6 24.0 1.3 1 0 0 1 1 1 0 Presenilin PEP_mutase PF13714.6 KZN89519.1 - 2e-50 171.5 0.7 2.6e-50 171.1 0.7 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KZN89519.1 - 8.7e-12 44.3 0.1 1.3e-11 43.7 0.1 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.15 KZN89519.1 - 0.00014 21.4 0.1 0.097 12.0 0.0 2.1 2 0 0 2 2 2 2 Ketopantoate hydroxymethyltransferase MFS_1 PF07690.16 KZN89520.1 - 7.8e-30 104.0 22.0 7.8e-30 104.0 22.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN89520.1 - 4.4e-13 48.9 15.9 9.6e-13 47.8 15.9 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 KZN89520.1 - 0.002 17.0 0.6 0.002 17.0 0.6 2.3 2 1 0 2 2 2 2 MFS_1 like family TRAM_LAG1_CLN8 PF03798.16 KZN89522.1 - 3.1e-38 131.5 19.7 3.1e-38 131.5 19.7 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KZN89522.1 - 3.8e-24 84.1 0.6 1e-23 82.8 0.1 2.1 2 0 0 2 2 2 1 TRAM1-like protein Sugar_tr PF00083.24 KZN89523.1 - 3.9e-111 372.1 21.4 4.8e-111 371.8 21.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN89523.1 - 6.1e-27 94.5 32.3 3.6e-26 91.9 22.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KZN89523.1 - 3.6e-05 22.4 0.5 8.4e-05 21.2 0.5 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 KZN89523.1 - 7.7e-05 21.8 0.3 0.00016 20.7 0.3 1.5 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM DUF4758 PF15950.5 KZN89523.1 - 0.045 14.1 0.0 0.077 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative sperm flagellar membrane protein DUF2530 PF10745.9 KZN89523.1 - 0.52 10.6 6.7 0.48 10.7 0.9 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Sulfatase PF00884.23 KZN89524.1 - 8.5e-25 87.8 0.6 1.6e-24 86.9 0.6 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KZN89524.1 - 1.1e-05 25.3 0.2 1.8e-05 24.6 0.2 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase ECF_trnsprt PF12822.7 KZN89524.1 - 0.034 14.3 1.3 0.33 11.0 2.8 1.8 1 1 1 2 2 2 0 ECF transporter, substrate-specific component DUF229 PF02995.17 KZN89524.1 - 0.13 10.8 0.1 0.19 10.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Transglut_core PF01841.19 KZN89526.1 - 6.2e-13 49.2 0.0 1.1e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 KZN89526.1 - 0.059 12.9 0.0 0.35 10.4 0.0 2.1 1 1 0 1 1 1 0 Transglutaminase-like domain Ras PF00071.22 KZN89527.1 - 5e-31 107.5 0.2 6.7e-31 107.1 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KZN89527.1 - 1.6e-23 83.2 0.1 2.8e-23 82.4 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KZN89527.1 - 1.4e-06 27.9 0.1 2.1e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KZN89527.1 - 0.00028 20.3 0.2 0.00039 19.8 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 KZN89527.1 - 0.011 14.6 0.2 2.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) G-alpha PF00503.20 KZN89527.1 - 0.033 13.4 1.1 0.64 9.1 0.1 2.3 1 1 1 2 2 2 0 G-protein alpha subunit CAF1C_H4-bd PF12265.8 KZN89528.1 - 4.9e-17 62.0 0.1 5.2e-16 58.7 0.0 2.6 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KZN89528.1 - 1.7e-15 57.1 8.8 1.3e-06 29.0 0.1 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN89528.1 - 8.7e-09 35.6 2.0 0.00058 20.1 0.2 3.4 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Fungal_trans PF04082.18 KZN89529.1 - 5.6e-25 87.9 2.6 9.3e-25 87.2 2.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KZN89529.1 - 1.4e-09 37.8 12.6 0.00025 21.3 4.0 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KZN89529.1 - 9e-07 29.1 5.8 9e-07 29.1 5.8 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KZN89529.1 - 0.007 17.1 18.8 0.057 14.3 3.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KZN89529.1 - 0.12 12.4 3.8 0.34 11.0 3.8 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KZN89529.1 - 0.22 11.9 2.0 0.82 10.0 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KZN89529.1 - 2.4 8.3 4.5 13 6.0 4.9 2.1 2 0 0 2 2 2 0 Zinc ribbon domain Clathrin PF00637.20 KZN89531.1 - 6.4e-25 87.7 1.2 5.1e-22 78.3 1.1 2.5 2 0 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.8 KZN89531.1 - 4.7e-18 65.1 0.7 1.1e-17 64.0 0.7 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 KZN89531.1 - 8.6e-08 32.1 7.7 1.6e-07 31.2 7.7 1.5 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 KZN89531.1 - 1.6e-06 27.9 7.1 3.2e-06 26.9 7.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_14 PF13428.6 KZN89531.1 - 3.5e-06 27.4 0.1 0.02 15.6 0.0 3.6 2 0 0 2 2 2 2 Tetratricopeptide repeat zf-RING_5 PF14634.6 KZN89531.1 - 0.00025 21.0 5.5 0.0005 20.0 5.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain TPR_11 PF13414.6 KZN89531.1 - 0.001 18.7 1.0 0.0021 17.7 0.1 2.1 2 0 0 2 2 1 1 TPR repeat zf-RING_2 PF13639.6 KZN89531.1 - 0.0014 19.0 6.4 0.0026 18.1 6.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KZN89531.1 - 0.0074 16.6 4.7 0.014 15.6 4.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain DUF4810 PF16068.5 KZN89531.1 - 0.0075 16.8 0.5 3 8.4 0.0 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4810) TPR_16 PF13432.6 KZN89531.1 - 0.013 16.2 0.2 0.11 13.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C3HC4 PF00097.25 KZN89531.1 - 0.028 14.3 5.3 0.053 13.4 5.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Katanin_con80 PF13925.6 KZN89531.1 - 0.031 14.3 0.0 1.9 8.5 0.0 2.7 2 0 0 2 2 2 0 con80 domain of Katanin Vps39_2 PF10367.9 KZN89531.1 - 0.081 13.4 3.5 0.059 13.8 0.8 2.2 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-RING_UBOX PF13445.6 KZN89531.1 - 0.085 12.9 4.8 0.18 11.9 4.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 KZN89531.1 - 0.3 11.2 1.9 0.68 10.0 1.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_12 PF13424.6 KZN89531.1 - 0.6 10.4 2.5 0.71 10.2 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KZN89531.1 - 0.71 10.1 3.3 1.7 8.9 0.1 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KZN89531.1 - 0.97 9.7 6.0 0.23 11.7 0.3 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat Nha1_C PF08619.10 KZN89532.1 - 3.9e-101 339.6 48.1 3.9e-101 339.6 48.1 1.9 1 1 1 2 2 2 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 KZN89532.1 - 9.5e-77 258.3 16.0 1.1e-76 258.1 16.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Serglycin PF04360.12 KZN89532.1 - 0.0051 16.8 8.3 0.013 15.5 8.3 1.6 1 0 0 1 1 1 1 Serglycin DUF21 PF01595.20 KZN89532.1 - 0.018 14.8 1.7 0.077 12.7 1.7 2.1 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain PX PF00787.24 KZN89533.1 - 7.1e-17 61.4 0.2 1.5e-16 60.4 0.2 1.5 1 0 0 1 1 1 1 PX domain Tmemb_cc2 PF10267.9 KZN89533.1 - 0.0095 15.1 0.5 0.015 14.5 0.5 1.3 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Prefoldin_3 PF13758.6 KZN89533.1 - 0.028 14.5 3.6 0.029 14.4 0.5 2.4 2 0 0 2 2 2 0 Prefoldin subunit Nucleoporin_FG PF13634.6 KZN89533.1 - 0.96 10.3 9.4 6.9 7.6 5.0 2.5 2 0 0 2 2 2 0 Nucleoporin FG repeat region Aldedh PF00171.22 KZN89534.1 - 1.1e-103 347.3 0.0 1.3e-103 347.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pro_dh PF01619.18 KZN89535.1 - 5.2e-61 206.8 0.0 6e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Proline dehydrogenase ATG2_CAD PF13329.6 KZN89536.1 - 0.036 13.8 0.3 0.075 12.8 0.3 1.5 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif DUF3530 PF12048.8 KZN89536.1 - 0.069 12.6 0.4 0.1 12.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Flavin_Reduct PF01613.18 KZN89538.1 - 8.1e-16 58.4 0.0 1.4e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Flavin reductase like domain Putative_PNPOx PF01243.20 KZN89538.1 - 0.019 15.2 0.0 0.041 14.1 0.0 1.5 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Stevor PF17410.2 KZN89539.1 - 0.015 14.9 0.0 0.019 14.5 0.0 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame TMEM154 PF15102.6 KZN89539.1 - 0.083 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 KZN89539.1 - 0.085 13.7 0.0 0.16 12.8 0.0 1.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain AAA PF00004.29 KZN89540.1 - 1.7e-07 31.7 0.1 8.8e-07 29.4 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KZN89540.1 - 6.9e-05 23.3 0.0 0.0002 21.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 KZN89540.1 - 0.00027 20.9 0.2 0.064 13.2 0.0 3.2 2 1 1 3 3 3 1 Rad17 P-loop domain AAA_22 PF13401.6 KZN89540.1 - 0.00062 20.1 0.0 0.0019 18.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KZN89540.1 - 0.004 17.7 0.0 0.01 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KZN89540.1 - 0.0051 15.9 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Cytidylate_kin PF02224.18 KZN89540.1 - 0.029 14.1 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase TIP49 PF06068.13 KZN89540.1 - 0.044 13.0 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_30 PF13604.6 KZN89540.1 - 0.073 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KZN89540.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KZN89540.1 - 0.18 11.3 0.0 0.37 10.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 KZN89540.1 - 0.2 10.9 0.0 0.2 10.9 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AT_hook PF02178.19 KZN89540.1 - 0.4 10.7 5.0 1.8 8.7 5.0 2.2 1 0 0 1 1 1 0 AT hook motif Utp8 PF10395.9 KZN89541.1 - 8.9e-10 37.7 0.8 5.2e-09 35.2 0.8 2.0 1 1 0 1 1 1 1 Utp8 family LRR_4 PF12799.7 KZN89542.1 - 1.7e-27 95.0 35.1 7.6e-05 23.0 0.2 9.2 6 3 4 10 10 10 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KZN89542.1 - 4.1e-22 77.7 34.1 7.8e-06 25.6 1.2 7.7 4 1 4 9 9 9 6 Leucine rich repeat LRR_9 PF14580.6 KZN89542.1 - 1.3e-08 34.6 14.4 0.019 14.4 1.5 4.5 1 1 4 5 5 5 5 Leucine-rich repeat LRR_6 PF13516.6 KZN89542.1 - 1.4e-07 31.0 27.2 0.57 10.4 0.0 9.3 11 0 0 11 11 11 5 Leucine Rich repeat LRR_1 PF00560.33 KZN89542.1 - 7.3e-05 22.8 27.3 4.4 8.2 0.0 10.0 11 1 0 11 11 11 3 Leucine Rich Repeat Cupin_1 PF00190.22 KZN89543.1 - 0.00015 21.4 0.0 0.00021 20.9 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KZN89543.1 - 0.0014 18.3 0.0 0.026 14.2 0.0 2.5 3 0 0 3 3 3 1 Cupin domain Cupin_4 PF08007.12 KZN89543.1 - 0.01 15.4 0.0 0.015 14.8 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein D5_N PF08706.11 KZN89543.1 - 0.13 12.5 0.1 0.18 12.0 0.1 1.3 1 0 0 1 1 1 0 D5 N terminal like Cupin_3 PF05899.12 KZN89543.1 - 0.17 11.6 0.0 0.5 10.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF861) MFS_1 PF07690.16 KZN89544.1 - 3.6e-29 101.8 32.9 2.3e-24 86.0 10.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PepSY_TM_like_2 PF16357.5 KZN89544.1 - 0.045 13.7 0.1 0.045 13.7 0.1 1.8 2 0 0 2 2 2 0 Putative PepSY_TM-like Phage_holin_5_1 PF06946.11 KZN89544.1 - 0.059 13.7 2.6 0.42 11.0 0.2 2.7 2 0 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 TraL PF07178.11 KZN89544.1 - 3.2 8.3 10.9 8 7.0 0.4 4.0 3 0 0 3 3 3 0 TraL protein DAO PF01266.24 KZN89545.1 - 6.2e-44 151.0 0.2 7.9e-44 150.7 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KZN89545.1 - 0.002 18.3 0.4 0.0051 17.0 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pkinase PF00069.25 KZN89547.1 - 5.2e-16 58.8 0.0 4.8e-14 52.3 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KZN89547.1 - 2.2e-08 33.7 0.0 8.8e-06 25.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Sulfatase PF00884.23 KZN89548.1 - 3.4e-18 66.1 0.3 3.4e-18 66.1 0.3 1.5 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 KZN89548.1 - 3.8e-06 26.7 0.1 6.6e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KZN89548.1 - 0.00033 19.4 0.0 0.00048 18.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF1501 PF07394.12 KZN89548.1 - 0.11 11.6 0.0 0.22 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Metalloenzyme PF01676.18 KZN89548.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily Mg_chelatase PF01078.21 KZN89548.1 - 0.22 10.9 0.1 0.75 9.1 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Methyltransf_23 PF13489.6 KZN89549.1 - 0.00039 20.3 0.0 0.00056 19.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TIP120 PF08623.10 KZN89550.1 - 3.7e-63 212.3 0.3 2.6e-62 209.5 0.0 2.5 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 KZN89550.1 - 7.9e-06 26.2 6.9 1 9.8 0.0 6.4 4 2 2 6 6 6 3 HEAT repeats HEAT PF02985.22 KZN89550.1 - 1e-05 25.3 15.6 0.87 10.0 0.0 8.8 11 0 0 11 11 11 2 HEAT repeat HEAT_EZ PF13513.6 KZN89550.1 - 0.0023 18.4 12.2 4.8 7.8 0.0 7.9 7 1 1 8 8 8 1 HEAT-like repeat IFRD PF05004.13 KZN89550.1 - 0.0042 16.2 0.4 0.95 8.5 0.0 3.3 3 0 0 3 3 3 1 Interferon-related developmental regulator (IFRD) UNC45-central PF11701.8 KZN89550.1 - 0.035 14.0 1.5 38 4.2 0.1 4.2 4 0 0 4 4 4 0 Myosin-binding striated muscle assembly central Arm PF00514.23 KZN89550.1 - 0.072 13.2 1.4 5.9 7.1 0.0 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat TAF6_C PF07571.13 KZN89550.1 - 0.087 13.2 0.1 2.2 8.6 0.0 3.0 1 1 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain Spectrin_like PF18373.1 KZN89550.1 - 0.16 12.0 0.1 0.47 10.6 0.1 1.8 1 0 0 1 1 1 0 Spectrin like domain HEAT_PBS PF03130.16 KZN89550.1 - 0.92 10.4 5.1 2.4 9.1 0.5 4.2 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat DBR1 PF05011.13 KZN89551.1 - 2.9e-39 134.7 0.0 6.5e-39 133.5 0.0 1.6 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain RTP1_C1 PF10363.9 KZN89552.1 - 8.1e-29 100.1 0.1 7.4e-28 97.0 0.1 2.7 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 KZN89552.1 - 7.6e-08 31.9 0.0 2.1e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 HEAT_EZ PF13513.6 KZN89552.1 - 0.4 11.2 6.3 8 7.1 0.0 4.5 4 0 0 4 4 4 0 HEAT-like repeat MscS_TM PF12794.7 KZN89552.1 - 1.6 7.5 3.1 3 6.6 3.1 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 zf-ZPR1 PF03367.13 KZN89553.1 - 2.4e-101 336.3 0.0 2.6e-52 176.9 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 KZN89553.1 - 0.011 15.8 1.0 0.87 9.6 0.1 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FeS PF04060.13 KZN89553.1 - 0.07 12.8 0.8 0.19 11.4 0.8 1.8 1 0 0 1 1 1 0 Putative Fe-S cluster APH PF01636.23 KZN89553.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cytochrome_C7 PF14522.6 KZN89553.1 - 0.55 10.3 5.7 0.18 11.8 0.6 2.6 2 2 0 2 2 2 0 Cytochrome c7 and related cytochrome c Acyl_transf_3 PF01757.22 KZN89554.1 - 4.4e-23 81.9 21.2 3e-22 79.2 21.2 2.2 1 1 0 1 1 1 1 Acyltransferase family ABC_membrane PF00664.23 KZN89555.1 - 2.2e-35 122.6 12.2 4.3e-35 121.7 12.2 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KZN89555.1 - 8.2e-33 113.8 0.0 1.6e-32 112.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KZN89555.1 - 1.5e-07 31.1 0.0 1.1e-06 28.3 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KZN89555.1 - 0.0092 15.7 0.1 0.025 14.3 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 KZN89555.1 - 0.011 15.9 0.3 0.31 11.3 0.3 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 KZN89555.1 - 0.017 15.5 0.1 0.045 14.1 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KZN89555.1 - 0.077 12.9 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 KZN89555.1 - 0.14 12.1 0.1 1.3 9.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KZN89555.1 - 0.16 12.2 0.2 1.9 8.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KZN89555.1 - 0.17 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain OppC_N PF12911.7 KZN89555.1 - 0.17 11.9 3.8 2.7 8.0 0.1 3.7 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C APH PF01636.23 KZN89556.1 - 4.1e-17 62.9 0.2 7.4e-10 39.2 0.0 3.0 2 1 0 2 2 2 2 Phosphotransferase enzyme family Glycos_transf_1 PF00534.20 KZN89556.1 - 1.4e-10 41.0 0.0 2.7e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KZN89556.1 - 1.2e-09 38.7 0.0 2.8e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Choline_kinase PF01633.20 KZN89556.1 - 0.00012 21.7 0.0 0.036 13.6 0.0 2.3 2 0 0 2 2 2 2 Choline/ethanolamine kinase WaaY PF06176.11 KZN89556.1 - 0.001 18.7 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pro_isomerase PF00160.21 KZN89557.1 - 2.7e-37 128.5 0.0 6.9e-37 127.2 0.0 1.5 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-CDGSH PF09360.10 KZN89557.1 - 0.085 13.1 0.2 0.25 11.6 0.1 1.8 2 0 0 2 2 2 0 Iron-binding zinc finger CDGSH type ORC6 PF05460.13 KZN89558.1 - 2.9e-92 309.7 0.0 3.4e-92 309.5 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Spc7_N PF15402.6 KZN89558.1 - 4.1 5.5 11.1 5.7 5.1 11.1 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Q_salvage PF10343.9 KZN89559.1 - 1.1e-135 451.7 0.0 1.4e-135 451.4 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DUF1563 PF07599.11 KZN89559.1 - 0.087 12.9 0.2 0.16 12.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) ThiF PF00899.21 KZN89560.1 - 4.4e-72 242.4 0.0 5.9e-72 241.9 0.0 1.1 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 KZN89560.1 - 1.3e-17 64.1 0.3 4.5e-17 62.4 0.3 2.0 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 KZN89560.1 - 3.2e-08 33.8 1.0 5.8e-06 26.4 0.5 2.5 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.20 KZN89560.1 - 0.002 18.2 0.0 0.009 16.1 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KZN89560.1 - 0.0021 18.5 0.1 0.0082 16.6 0.0 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding UPF0561 PF10573.9 KZN89560.1 - 0.098 12.8 0.3 0.24 11.6 0.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 Topoisom_bac PF01131.20 KZN89560.1 - 0.14 11.1 0.4 0.24 10.4 0.4 1.3 1 0 0 1 1 1 0 DNA topoisomerase Sec20 PF03908.13 KZN89560.1 - 0.18 11.8 0.7 2.7 8.0 0.1 2.6 2 0 0 2 2 2 0 Sec20 adh_short PF00106.25 KZN89561.1 - 3.1e-35 121.4 2.2 3.4e-24 85.4 0.1 2.4 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KZN89561.1 - 4.3e-35 121.4 0.4 1.2e-29 103.6 0.0 2.4 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN89561.1 - 3.1e-10 40.2 1.6 4.6e-09 36.4 0.4 2.6 2 1 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 KZN89561.1 - 7e-06 25.4 0.1 0.0006 19.0 0.1 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KZN89561.1 - 8.3e-06 25.4 0.0 8.4e-05 22.1 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KZN89561.1 - 0.00076 19.6 0.1 0.02 15.0 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KZN89561.1 - 0.0016 19.0 0.1 0.0035 17.9 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 KZN89561.1 - 0.0096 15.8 1.1 1.2 9.0 0.1 2.2 1 1 1 2 2 2 2 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KZN89561.1 - 0.07 13.4 0.3 0.44 10.8 0.3 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Skp1_POZ PF03931.15 KZN89562.1 - 1.1e-05 25.5 0.0 1.5e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain zf-C3HC4_3 PF13920.6 KZN89563.1 - 9.2e-09 35.0 11.9 1.5e-08 34.3 11.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KZN89563.1 - 0.12 12.2 12.5 0.23 11.3 12.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Malic_M PF03949.15 KZN89564.1 - 9.1e-91 303.7 0.0 1.2e-90 303.3 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KZN89564.1 - 2.5e-65 219.7 0.4 3.9e-65 219.1 0.0 1.5 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain Na_Ca_ex PF01699.24 KZN89565.1 - 7.2e-10 39.0 32.2 1.2e-06 28.6 11.1 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein PspB PF06667.12 KZN89565.1 - 0.65 10.1 3.4 2.3 8.3 3.4 1.9 1 0 0 1 1 1 0 Phage shock protein B NACHT PF05729.12 KZN89566.1 - 2.9e-07 30.5 0.0 1.4e-06 28.3 0.0 2.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KZN89566.1 - 2e-06 28.3 1.9 1e-05 26.0 0.0 3.1 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KZN89566.1 - 0.00027 21.2 0.1 0.0018 18.5 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KZN89566.1 - 0.0031 18.1 0.0 0.018 15.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KZN89566.1 - 0.02 14.2 0.2 0.12 11.6 0.0 2.4 3 0 0 3 3 3 0 Zeta toxin AAA_30 PF13604.6 KZN89566.1 - 0.03 14.1 0.1 0.085 12.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KZN89566.1 - 0.068 13.7 0.0 0.32 11.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter ATP_bind_1 PF03029.17 KZN89566.1 - 0.074 12.8 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 KZN89566.1 - 0.088 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KZN89566.1 - 0.096 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 KZN89566.1 - 0.11 12.9 0.0 0.33 11.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Ploopntkinase1 PF18748.1 KZN89566.1 - 0.15 11.6 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 CFEM PF05730.11 KZN89568.1 - 3.6e-15 55.8 10.6 6.5e-15 55.0 10.6 1.4 1 0 0 1 1 1 1 CFEM domain DNA_pol_delta_4 PF04081.13 KZN89569.1 - 2.3e-34 118.6 1.2 3.4e-34 118.0 1.2 1.3 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 LolA_like PF17131.4 KZN89569.1 - 0.049 13.4 0.1 0.07 12.9 0.1 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein-sorting protein Arrestin_C PF02752.22 KZN89570.1 - 1.2e-13 51.7 0.3 5.4e-13 49.6 0.0 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain MFS_1 PF07690.16 KZN89571.1 - 3.4e-42 144.6 18.0 3.4e-42 144.6 18.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN89571.1 - 3.2e-13 49.4 4.1 3.2e-13 49.4 4.1 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KZN89571.1 - 0.0019 16.6 2.3 0.0019 16.6 2.3 2.0 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 KZN89571.1 - 0.0067 14.9 2.4 0.0094 14.4 2.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FPN1 PF06963.12 KZN89571.1 - 0.021 13.4 0.5 0.043 12.4 0.0 1.8 2 0 0 2 2 2 0 Ferroportin1 (FPN1) MFS_3 PF05977.13 KZN89571.1 - 0.14 10.5 3.5 0.035 12.5 0.7 1.5 2 0 0 2 2 2 0 Transmembrane secretion effector MFS_1_like PF12832.7 KZN89571.1 - 0.5 9.2 10.3 3.2 6.5 3.3 3.0 3 1 0 3 3 3 0 MFS_1 like family Gly_kinase PF02595.15 KZN89572.1 - 1.6e-126 422.2 3.0 1.8e-126 422.1 3.0 1.0 1 0 0 1 1 1 1 Glycerate kinase family Melibiase PF02065.18 KZN89574.1 - 5.8e-150 499.0 0.0 7.4e-150 498.7 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 KZN89574.1 - 9.7e-82 274.3 0.0 1.4e-81 273.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 KZN89574.1 - 4.3e-23 81.6 0.0 1e-22 80.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain GHL10 PF02638.15 KZN89574.1 - 3.2e-07 29.7 0.0 5.1e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 tRNA_int_end_N2 PF12928.7 KZN89576.1 - 8.5e-29 99.5 0.0 1.7e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 KZN89576.1 - 0.0078 15.9 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain ThiF PF00899.21 KZN89577.1 - 2.6e-14 53.2 0.0 1.8e-13 50.5 0.0 2.3 1 1 0 1 1 1 1 ThiF family Rib_5-P_isom_A PF06026.14 KZN89578.1 - 7.5e-44 149.4 0.0 1.2e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 KZN89578.1 - 0.019 14.9 0.0 5.7 6.9 0.0 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain DND1_DSRM PF14709.7 KZN89578.1 - 0.18 12.1 0.0 2.6 8.4 0.0 2.2 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 WD40 PF00400.32 KZN89579.1 - 6e-15 55.4 1.9 0.019 15.8 0.2 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat SGL PF08450.12 KZN89579.1 - 0.05 13.2 0.0 0.25 10.9 0.0 2.0 1 1 1 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region ANAPC4_WD40 PF12894.7 KZN89579.1 - 0.16 12.3 0.1 15 6.0 0.0 3.4 3 2 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4979 PF16351.5 KZN89579.1 - 0.16 12.2 0.0 2.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4979) ATP_bind_1 PF03029.17 KZN89580.1 - 1.9e-78 263.6 0.0 2.5e-78 263.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 KZN89580.1 - 0.0009 18.3 0.1 0.0034 16.4 0.0 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_31 PF13614.6 KZN89580.1 - 0.0017 18.3 0.0 2.3 8.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KZN89580.1 - 0.0044 17.1 0.0 0.039 14.0 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KZN89580.1 - 0.023 14.9 0.0 0.05 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KZN89580.1 - 0.045 14.3 0.3 0.24 11.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain CLP1_P PF16575.5 KZN89580.1 - 0.054 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_10 PF12846.7 KZN89580.1 - 0.062 12.2 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.6 KZN89580.1 - 0.066 13.5 0.0 0.15 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 KZN89580.1 - 0.074 12.5 0.6 0.31 10.4 0.2 2.2 2 1 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RNA_helicase PF00910.22 KZN89580.1 - 0.15 12.4 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 KZN89580.1 - 0.16 12.4 2.1 0.28 11.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain RNase_P_Rpp14 PF01900.19 KZN89581.1 - 2.8e-36 123.9 0.0 4.2e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 Rpp14/Pop5 family Citrate_synt PF00285.21 KZN89582.1 - 3.3e-21 75.8 0.0 1.9e-18 66.7 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 KZN89582.1 - 2.4e-19 69.8 0.0 1.1e-18 67.7 0.0 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KZN89582.1 - 1.2e-14 54.5 0.1 2.1e-14 53.6 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KZN89582.1 - 2.5e-06 27.3 0.0 6e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CEP1-DNA_bind PF09287.10 KZN89582.1 - 0.23 11.1 0.0 0.5 10.0 0.0 1.5 1 0 0 1 1 1 0 CEP-1, DNA binding Citrate_bind PF16114.5 KZN89583.1 - 3.2e-87 290.6 0.0 4.3e-87 290.2 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 KZN89583.1 - 1e-08 35.0 0.0 1.5e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Reovirus_M2 PF05993.12 KZN89583.1 - 0.033 12.3 0.1 0.051 11.7 0.1 1.2 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) MBOAT_2 PF13813.6 KZN89584.1 - 1.1e-22 80.0 1.0 1.1e-22 80.0 1.0 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family PhyH PF05721.13 KZN89585.1 - 0.13 12.5 0.2 0.62 10.3 0.2 2.0 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) Allexi_40kDa PF05549.11 KZN89586.1 - 0.0021 17.6 3.3 0.003 17.1 3.3 1.2 1 0 0 1 1 1 1 Allexivirus 40kDa protein Lebercilin PF15619.6 KZN89586.1 - 0.0026 17.4 9.1 0.0038 16.9 9.1 1.2 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease OmpH PF03938.14 KZN89586.1 - 0.0037 17.6 11.5 0.005 17.2 11.5 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.15 KZN89586.1 - 0.0084 15.7 1.5 0.0098 15.5 1.5 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit Fmp27_WPPW PF10359.9 KZN89586.1 - 0.011 14.6 5.4 0.014 14.3 5.4 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CCDC158 PF15921.5 KZN89586.1 - 0.015 13.2 2.2 0.019 12.8 2.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 DUF4472 PF14739.6 KZN89586.1 - 0.015 16.0 7.5 0.022 15.5 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) DUF5082 PF16888.5 KZN89586.1 - 0.016 15.5 7.0 0.016 15.5 7.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF4349 PF14257.6 KZN89586.1 - 0.12 11.8 2.9 0.21 11.0 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Spc24 PF08286.11 KZN89586.1 - 0.14 12.4 7.2 0.21 11.8 7.2 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Phage_Mu_Gam PF07352.12 KZN89586.1 - 0.14 12.0 3.9 0.22 11.4 3.9 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein SbcD_C PF12320.8 KZN89586.1 - 0.17 12.2 2.7 0.3 11.4 0.8 2.0 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Fib_alpha PF08702.10 KZN89586.1 - 0.23 11.7 8.5 0.33 11.1 8.5 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Mod_r PF07200.13 KZN89586.1 - 0.38 10.8 13.5 1.5 8.9 13.5 1.8 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein V-ATPase_G_2 PF16999.5 KZN89586.1 - 0.51 10.8 3.3 0.88 10.0 3.3 1.3 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF3573 PF12097.8 KZN89586.1 - 0.71 8.6 4.1 0.85 8.4 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) FapA PF03961.13 KZN89586.1 - 1.2 7.6 8.0 1.5 7.3 8.0 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Nup88 PF10168.9 KZN89586.1 - 1.5 6.6 8.9 1.9 6.2 8.9 1.0 1 0 0 1 1 1 0 Nuclear pore component TMPIT PF07851.13 KZN89586.1 - 2.2 7.5 7.0 2.9 7.0 7.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein Ly49 PF08391.10 KZN89586.1 - 9.3 6.6 8.6 14 6.1 8.6 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region XAP5 PF04921.14 KZN89587.1 - 3.7e-87 292.3 0.0 5.4e-87 291.8 0.0 1.2 1 0 0 1 1 1 1 XAP5, circadian clock regulator DUF4604 PF15377.6 KZN89587.1 - 0.004 17.6 3.6 0.004 17.6 3.6 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4604) Pol_alpha_B_N PF08418.10 KZN89587.1 - 0.11 12.5 4.6 0.18 11.8 4.6 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Fip1 PF05182.13 KZN89588.1 - 6.4e-20 70.4 1.3 1.2e-19 69.6 1.3 1.4 1 0 0 1 1 1 1 Fip1 motif Cpn10 PF00166.21 KZN89589.1 - 7.1e-29 99.7 0.0 8e-29 99.6 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit TauD PF02668.16 KZN89591.1 - 1.3e-51 176.0 0.2 1.6e-51 175.7 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Nucleoporin_FG PF13634.6 KZN89592.1 - 1.1e-09 39.0 62.9 1e-07 32.7 39.6 3.4 1 1 2 3 3 3 3 Nucleoporin FG repeat region DUF1664 PF07889.12 KZN89592.1 - 0.0047 16.9 0.6 0.18 11.9 0.1 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1664) WD40 PF00400.32 KZN89593.1 - 0.00047 20.9 8.1 8.1 7.5 0.1 6.3 6 0 0 6 6 6 1 WD domain, G-beta repeat Lactonase PF10282.9 KZN89593.1 - 0.0097 15.2 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller ANAPC4_WD40 PF12894.7 KZN89593.1 - 0.012 15.9 0.0 2.7 8.4 0.0 3.5 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain HAD_2 PF13419.6 KZN89594.1 - 7.3e-14 52.2 0.0 1.1e-13 51.7 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KZN89594.1 - 1.5e-07 31.9 0.0 2.1e-06 28.2 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KZN89594.1 - 0.0073 16.3 0.0 0.025 14.7 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like NIR_SIR PF01077.22 KZN89594.1 - 0.03 13.8 0.0 0.032 13.7 0.0 1.3 1 1 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain TPR_1 PF00515.28 KZN89595.1 - 7.1e-07 28.8 1.3 0.0065 16.2 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KZN89595.1 - 4.1e-06 27.0 0.3 1e-05 25.7 0.3 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 KZN89595.1 - 6.2e-06 25.9 0.2 0.063 13.4 0.1 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KZN89595.1 - 0.00054 19.8 0.6 1.5 9.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KZN89595.1 - 0.0022 18.6 0.8 0.14 12.8 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KZN89595.1 - 0.01 15.5 2.3 0.017 14.8 0.2 2.4 2 1 0 2 2 2 0 TPR repeat Mis14 PF08641.12 KZN89595.1 - 0.12 12.7 7.5 0.14 12.5 2.3 2.5 3 0 0 3 3 3 0 Kinetochore protein Mis14 like DUF2201_N PF13203.6 KZN89595.1 - 0.49 10.0 4.6 0.5 9.9 2.9 1.7 1 1 1 2 2 2 0 Putative metallopeptidase domain TPR_14 PF13428.6 KZN89595.1 - 1.1 10.3 3.3 2.4 9.2 0.0 3.2 4 1 1 5 5 5 0 Tetratricopeptide repeat dUTPase PF00692.19 KZN89598.1 - 7.4e-10 38.6 0.0 1.1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 dUTPase AMP-binding PF00501.28 KZN89599.1 - 1.4e-89 300.7 0.0 1.7e-89 300.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KZN89599.1 - 7.1e-12 46.1 0.0 1.9e-11 44.8 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 KZN89600.1 - 6.7e-52 176.6 33.8 2.5e-46 158.2 19.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KZN89600.1 - 1.1e-07 30.5 4.2 0.0079 14.5 2.1 3.4 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 KZN89600.1 - 1.6e-06 26.8 17.3 1.8e-06 26.7 9.0 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector MFS_1_like PF12832.7 KZN89600.1 - 0.00032 19.7 12.5 0.015 14.2 7.4 2.8 2 1 0 2 2 2 2 MFS_1 like family PTR2 PF00854.21 KZN89600.1 - 0.28 10.0 9.5 0.36 9.6 0.6 2.5 2 0 0 2 2 2 0 POT family HKR_ArcB_TM PF18415.1 KZN89600.1 - 3.1 8.7 6.9 2.3 9.1 0.5 3.5 3 0 0 3 3 3 0 Histidine kinase receptor ArcB trans-membrane domain 3Beta_HSD PF01073.19 KZN89601.1 - 3.5e-11 42.6 0.0 5.6e-11 42.0 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KZN89601.1 - 1.6e-10 40.9 0.0 4.3e-10 39.5 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KZN89601.1 - 1.8e-07 31.2 0.1 4.2e-07 30.0 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KZN89601.1 - 2.7e-07 30.0 0.0 0.0019 17.4 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 KZN89601.1 - 2.1e-05 24.2 0.1 6.4e-05 22.6 0.1 1.8 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KZN89601.1 - 5e-05 22.9 0.1 0.00023 20.6 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KZN89601.1 - 0.00015 21.3 0.1 0.00072 19.1 0.0 2.1 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.10 KZN89601.1 - 0.0019 18.1 0.1 0.029 14.3 0.1 2.3 1 1 0 1 1 1 1 KR domain FeS_assembly_P PF01883.19 KZN89601.1 - 0.051 13.7 0.1 9.3 6.5 0.0 3.4 3 1 1 4 4 4 0 Iron-sulfur cluster assembly protein Response_reg PF00072.24 KZN89601.1 - 0.12 12.6 0.0 8.9 6.5 0.0 3.3 4 0 0 4 4 4 0 Response regulator receiver domain DUF3112 PF11309.8 KZN89602.1 - 3.6e-13 49.5 4.7 4.7e-09 36.0 0.3 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3112) DUF4281 PF14108.6 KZN89602.1 - 0.13 12.6 4.9 0.52 10.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4281) Abhydrolase_9_N PF15420.6 KZN89602.1 - 0.74 9.8 6.5 0.43 10.5 3.4 2.0 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus DUF4271 PF14093.6 KZN89602.1 - 2.2 8.2 16.1 0.1 12.5 9.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) Metallophos PF00149.28 KZN89603.1 - 5.1e-38 131.6 0.4 8.4e-38 130.9 0.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KZN89603.1 - 0.025 15.0 0.0 0.048 14.1 0.0 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain PI31_Prot_N PF11566.8 KZN89604.1 - 2.8e-50 170.3 0.0 3.4e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 KZN89604.1 - 3.6e-18 66.5 17.4 3.6e-18 66.5 17.4 3.5 3 1 0 3 3 3 1 PI31 proteasome regulator Acyl-CoA_dh_1 PF00441.24 KZN89605.1 - 3e-29 102.2 2.4 6.1e-29 101.2 2.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 KZN89605.1 - 5.4e-21 74.5 0.1 1.2e-20 73.4 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 KZN89605.1 - 2.4e-19 69.3 0.2 4.9e-19 68.3 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KZN89605.1 - 9.4e-08 32.7 0.5 2.3e-07 31.5 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KZN89605.1 - 0.0024 18.1 0.0 0.0057 16.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF2153 PF09921.9 KZN89605.1 - 0.044 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) UvdE PF03851.14 KZN89606.1 - 3.2e-112 374.3 0.0 4.2e-112 373.9 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE Methyltransf_23 PF13489.6 KZN89607.1 - 0.02 14.7 0.0 0.051 13.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KZN89607.1 - 0.021 15.6 0.0 0.07 13.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain ADH_N PF08240.12 KZN89607.1 - 0.029 14.2 0.1 0.05 13.5 0.1 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.16 KZN89608.1 - 2.9e-31 108.7 81.6 2.1e-26 92.7 45.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KZN89608.1 - 0.00024 20.5 33.4 0.00033 20.1 33.4 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Hexokinase_1 PF00349.21 KZN89609.1 - 3.6e-48 164.1 0.0 5.1e-48 163.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 KZN89609.1 - 3.6e-43 147.7 0.0 5.7e-43 147.1 0.0 1.3 1 0 0 1 1 1 1 Hexokinase TatD_DNase PF01026.21 KZN89610.1 - 2.9e-42 144.8 0.0 3.4e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase BKACE PF05853.12 KZN89610.1 - 0.035 13.4 0.0 0.044 13.1 0.0 1.3 1 1 0 1 1 1 0 beta-keto acid cleavage enzyme RNA_pol_Rpc4 PF05132.14 KZN89611.1 - 0.031 14.7 11.2 0.28 11.6 6.5 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 Utp14 PF04615.13 KZN89611.1 - 0.11 11.0 11.5 0.16 10.6 11.5 1.1 1 0 0 1 1 1 0 Utp14 protein Apt1 PF10351.9 KZN89611.1 - 1.4 7.7 16.9 1.1 8.1 13.4 1.9 2 0 0 2 2 2 0 Golgi-body localisation protein domain RR_TM4-6 PF06459.12 KZN89611.1 - 1.5 8.6 11.7 5.5 6.7 7.3 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SOG2 PF10428.9 KZN89611.1 - 2.1 7.5 26.1 3.3 6.8 26.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF3408 PF11888.8 KZN89611.1 - 4 7.6 12.5 2.7 8.1 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) CCSAP PF15748.5 KZN89611.1 - 4.7 7.3 21.4 1.6 8.9 13.7 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated GREB1 PF15782.5 KZN89611.1 - 7.7 3.5 13.7 9.4 3.2 13.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hid1 PF12722.7 KZN89611.1 - 8.5 4.4 13.5 4.7 5.2 9.6 1.9 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein APH PF01636.23 KZN89613.1 - 3.1e-15 56.8 0.0 4.8e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KZN89613.1 - 0.038 13.3 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Fructosamin_kin PF03881.14 KZN89613.1 - 0.092 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase MARVEL PF01284.23 KZN89615.1 - 0.23 11.5 15.1 1.6 8.8 15.6 1.9 1 1 1 2 2 2 0 Membrane-associating domain CENP-S PF15630.6 KZN89616.1 - 3.7e-35 120.1 0.0 4.8e-35 119.8 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KZN89616.1 - 4.5e-09 36.4 0.0 5.3e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 KZN89616.1 - 3.5e-05 23.7 0.0 5.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated PGA2 PF07543.12 KZN89617.1 - 2.7e-45 153.7 2.7 3.7e-45 153.3 2.7 1.2 1 0 0 1 1 1 1 Protein trafficking PGA2 RNA_pol_Rpb2_5 PF04567.17 KZN89617.1 - 0.36 11.4 3.8 0.36 11.4 0.7 2.4 3 0 0 3 3 3 0 RNA polymerase Rpb2, domain 5 MMS1_N PF10433.9 KZN89618.1 - 3.5e-135 451.4 0.0 4.9e-135 450.9 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KZN89618.1 - 1.9e-75 254.2 0.2 1.3e-72 244.8 0.0 3.4 4 0 0 4 4 4 2 CPSF A subunit region ANAPC4_WD40 PF12894.7 KZN89618.1 - 4.8e-05 23.6 0.0 0.014 15.7 0.1 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain FAD_binding_1 PF00667.20 KZN89619.1 - 1.8e-62 210.8 0.0 2.9e-62 210.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KZN89619.1 - 1.8e-35 122.3 2.0 4e-35 121.1 2.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KZN89619.1 - 7.2e-20 71.7 0.0 1.3e-18 67.7 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KZN89619.1 - 0.083 13.1 0.1 0.45 10.7 0.0 2.2 2 0 0 2 2 2 0 Flavodoxin domain MOR2-PAG1_N PF14222.6 KZN89620.1 - 1.2e-209 697.8 0.0 2e-209 697.1 0.0 1.3 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KZN89620.1 - 8.1e-90 301.1 0.0 2.8e-89 299.3 0.0 2.0 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KZN89620.1 - 4.7e-33 114.0 12.8 2.5e-12 45.4 0.2 4.0 2 1 1 3 3 3 3 Cell morphogenesis central region HEAT PF02985.22 KZN89620.1 - 0.56 10.6 1.8 16 6.1 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat NAD_binding_2 PF03446.15 KZN89621.1 - 4.1e-31 108.3 0.1 6.6e-31 107.6 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KZN89621.1 - 1.7e-29 102.5 0.0 3.1e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 KZN89621.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KZN89621.1 - 0.026 15.1 0.0 0.054 14.1 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TGS PF02824.21 KZN89621.1 - 0.029 14.4 0.0 0.091 12.8 0.0 1.8 1 0 0 1 1 1 0 TGS domain TrkA_N PF02254.18 KZN89621.1 - 0.032 14.5 0.2 0.84 9.9 0.0 2.3 1 1 1 2 2 2 0 TrkA-N domain RRM_1 PF00076.22 KZN89622.1 - 2.8e-21 75.1 0.0 1.6e-09 37.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAPS_reduct PF01507.19 KZN89623.1 - 1.6e-24 86.9 0.0 6.2e-23 81.7 0.0 2.2 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DnaJ PF00226.31 KZN89624.1 - 5.9e-14 51.9 0.7 5.9e-14 51.9 0.7 2.2 3 0 0 3 3 3 1 DnaJ domain HSP20 PF00011.21 KZN89624.1 - 0.016 15.3 1.0 4.6 7.5 1.0 2.7 2 1 0 2 2 2 0 Hsp20/alpha crystallin family FKBP26_C PF18046.1 KZN89624.1 - 0.031 14.4 0.1 0.094 12.8 0.0 1.8 2 0 0 2 2 2 0 FKBP26_C-terminal LMBR1 PF04791.16 KZN89624.1 - 1.8 7.4 4.8 2 7.2 4.8 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DEAD PF00270.29 KZN89625.1 - 8.2e-47 159.2 0.0 1.4e-46 158.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KZN89625.1 - 1.7e-23 83.1 0.0 8.3e-23 80.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KZN89625.1 - 5.1e-20 71.5 0.0 1.3e-19 70.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KZN89625.1 - 7e-08 32.7 0.5 1.7e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AA_permease PF00324.21 KZN89626.1 - 4e-127 424.7 37.2 4.6e-127 424.5 37.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KZN89626.1 - 3.7e-44 151.2 42.1 4.5e-44 150.9 42.1 1.1 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.7 KZN89626.1 - 9.2 7.1 17.0 0.15 12.8 0.7 4.4 4 0 0 4 4 4 0 PrgI family protein DUF2576 PF10845.8 KZN89627.1 - 0.044 13.4 3.8 0.56 9.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2576) Dicty_CAR PF05462.11 KZN89630.1 - 6.6e-11 41.9 10.9 6.6e-11 41.9 10.9 1.6 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 KZN89630.1 - 4.9e-08 32.6 0.2 6.4e-08 32.2 0.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 KZN89630.1 - 1.6e-06 28.0 12.6 3.1e-06 27.1 12.6 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Frizzled PF01534.17 KZN89630.1 - 0.12 11.3 15.7 2 7.4 15.7 2.3 1 1 0 1 1 1 0 Frizzled/Smoothened family membrane region Zn_clus PF00172.18 KZN89631.1 - 1.2e-06 28.5 5.0 2.5e-06 27.5 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.19 KZN89632.1 - 4.1e-53 180.7 0.0 6.5e-33 114.4 0.0 2.1 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 KZN89632.1 - 2.4e-34 118.9 0.0 4.1e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KZN89632.1 - 3.4e-05 24.0 0.0 0.00019 21.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KZN89632.1 - 0.00073 18.7 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KZN89632.1 - 0.025 13.8 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KZN89632.1 - 0.028 14.0 0.3 0.065 12.8 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KZN89632.1 - 0.043 12.5 0.1 0.069 11.8 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 KZN89632.1 - 0.046 12.8 1.4 0.11 11.5 0.4 1.9 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.16 KZN89632.1 - 0.053 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 KZN89632.1 - 0.054 12.7 0.1 0.41 9.8 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KZN89633.1 - 1.2e-26 94.1 0.0 1.8e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KZN89633.1 - 4.7e-14 52.4 0.6 2.1e-13 50.3 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KZN89633.1 - 6.9e-09 35.7 1.1 2.7e-08 33.8 1.1 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KZN89633.1 - 4.9e-08 32.6 0.0 3.3e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KZN89633.1 - 2.4e-07 30.5 0.1 3.4e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KZN89633.1 - 1.2e-06 28.0 0.1 1.9e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KZN89633.1 - 1.5e-06 27.6 0.4 2.4e-06 26.9 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KZN89633.1 - 1.1e-05 24.4 0.2 2.6e-05 23.1 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KZN89633.1 - 2.1e-05 23.8 0.0 3.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KZN89633.1 - 2.6e-05 23.5 0.2 0.00015 21.0 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 KZN89633.1 - 5e-05 22.7 0.3 0.00015 21.1 0.1 1.8 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.27 KZN89633.1 - 0.00018 22.0 0.5 0.0029 18.1 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KZN89633.1 - 0.0012 18.2 0.0 0.026 13.8 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KZN89633.1 - 0.011 15.1 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Prenylcys_lyase PF07156.14 KZN89633.1 - 0.017 14.3 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Prenylcysteine lyase 3HCDH_N PF02737.18 KZN89633.1 - 0.021 14.7 0.2 0.039 13.8 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KZN89633.1 - 0.093 12.7 0.5 0.31 11.0 0.1 2.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KZN89633.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Isy1 PF06246.12 KZN89633.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Isy1-like splicing family Amino_oxidase PF01593.24 KZN89634.1 - 6.7e-08 32.2 0.1 6.9e-08 32.2 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FMO-like PF00743.19 KZN89635.1 - 2.5e-14 52.6 0.1 1.1e-11 43.9 0.1 2.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KZN89635.1 - 3.2e-13 49.6 0.0 1.6e-12 47.3 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KZN89635.1 - 4e-09 36.1 0.0 9.8e-05 21.6 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KZN89635.1 - 1.8e-08 34.4 0.0 2.8e-07 30.7 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KZN89635.1 - 4.3e-08 32.7 0.0 4e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KZN89635.1 - 6e-08 32.2 0.0 2.5e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Mqo PF06039.15 KZN89635.1 - 1.9e-07 30.0 0.0 0.0043 15.7 0.0 2.6 2 1 1 3 3 3 2 Malate:quinone oxidoreductase (Mqo) DAO PF01266.24 KZN89635.1 - 1.8e-06 27.8 0.0 0.00016 21.4 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KZN89635.1 - 0.00026 20.2 0.0 0.0068 15.5 0.0 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.27 KZN89635.1 - 0.0009 19.8 0.0 2.1 9.0 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KZN89635.1 - 0.011 15.8 0.3 0.81 9.7 0.0 3.3 4 0 0 4 4 4 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KZN89635.1 - 0.034 13.2 0.0 0.08 12.0 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.20 KZN89635.1 - 0.093 12.8 0.0 1.9 8.5 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KZN89636.1 - 2e-14 53.9 0.1 3.8e-14 53.1 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Sacchrp_dh_C PF16653.5 KZN89636.1 - 0.059 13.5 0.0 2.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase C-terminal domain MGC-24 PF05283.11 KZN89637.1 - 0.019 15.4 2.4 0.025 15.0 2.4 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Rsbr_N PF08678.10 KZN89638.1 - 0.099 12.7 0.0 0.66 10.1 0.0 2.1 2 0 0 2 2 2 0 Rsbr N terminal Cutinase PF01083.22 KZN89641.1 - 1.2e-47 162.2 0.6 1.4e-47 162.0 0.6 1.0 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 KZN89641.1 - 0.00038 20.4 0.0 0.00058 19.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.11 KZN89641.1 - 0.0059 16.2 0.0 0.0083 15.7 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain DUF2974 PF11187.8 KZN89641.1 - 0.18 11.3 0.1 0.23 11.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) FA_hydroxylase PF04116.13 KZN89642.1 - 2.2e-25 89.5 18.5 2.2e-25 89.5 18.5 2.0 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily DUF2236 PF09995.9 KZN89642.1 - 0.0049 17.1 0.0 0.0078 16.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) FAM198 PF15051.6 KZN89642.1 - 0.069 12.0 0.0 0.14 11.0 0.0 1.5 1 0 0 1 1 1 0 FAM198 protein Glyoxalase PF00903.25 KZN89643.1 - 1e-05 25.8 0.0 0.00012 22.3 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Sacchrp_dh_NADP PF03435.18 KZN89644.1 - 6.8e-12 45.8 0.1 1.5e-11 44.6 0.1 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Sacchrp_dh_C PF16653.5 KZN89644.1 - 0.027 14.6 0.0 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase C-terminal domain adh_short PF00106.25 KZN89644.1 - 0.11 11.9 0.1 0.83 9.1 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase DAO PF01266.24 KZN89645.1 - 7.4e-29 101.4 0.0 8.7e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KZN89645.1 - 1.3e-05 25.4 0.1 3e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KZN89645.1 - 0.0037 16.5 0.0 0.0062 15.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KZN89645.1 - 0.015 14.5 0.0 0.041 13.1 0.0 1.6 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 KZN89645.1 - 0.018 15.1 0.1 0.15 12.1 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KZN89645.1 - 0.021 15.4 0.0 0.07 13.7 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AAT PF03417.16 KZN89646.1 - 5.9e-47 160.2 0.0 7.2e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DIOX_N PF14226.6 KZN89647.1 - 2.2e-16 60.7 0.1 3.3e-16 60.1 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KZN89647.1 - 1.4e-15 57.6 0.2 4.2e-15 56.1 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Condensation PF00668.20 KZN89648.1 - 2.3e-274 910.0 2.8 1.3e-98 330.7 1.0 4.6 5 0 0 5 5 5 4 Condensation domain AMP-binding PF00501.28 KZN89648.1 - 5e-245 812.7 0.0 9.6e-86 288.0 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme PP-binding PF00550.25 KZN89648.1 - 1.9e-43 146.7 0.1 6.1e-14 52.1 0.1 4.0 3 0 0 3 3 3 3 Phosphopantetheine attachment site Thioesterase PF00975.20 KZN89648.1 - 7.4e-29 101.5 0.0 1.8e-28 100.3 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain AMP-binding_C PF13193.6 KZN89648.1 - 1e-25 90.5 0.0 9e-08 33.0 0.0 3.9 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain LpxD PF04613.14 KZN89648.1 - 0.02 14.6 0.4 2.7 7.8 0.1 3.0 3 0 0 3 3 3 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Abhydrolase_6 PF12697.7 KZN89648.1 - 0.036 14.7 0.0 0.15 12.6 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family RHH_5 PF07878.11 KZN89648.1 - 0.071 13.0 0.0 0.23 11.3 0.0 1.9 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 GH3 PF03321.13 KZN89648.1 - 0.076 11.9 0.7 1.8 7.3 0.0 3.2 4 0 0 4 4 4 0 GH3 auxin-responsive promoter AATase PF07247.12 KZN89648.1 - 0.12 10.9 0.1 0.72 8.3 0.1 2.2 2 0 0 2 2 2 0 Alcohol acetyltransferase Peptidase_S41 PF03572.18 KZN89649.1 - 3.7e-09 36.3 0.0 8.3e-09 35.2 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 Methyltransf_32 PF13679.6 KZN89650.1 - 2.3e-21 76.4 0.0 5.4e-21 75.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain DUF1180 PF06679.12 KZN89652.1 - 1 9.8 5.1 1.2 9.5 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Glyco_transf_54 PF04666.13 KZN89655.1 - 1.3e-10 40.7 0.0 1.4e-08 34.0 0.0 2.8 2 1 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DMT_YdcZ PF04657.13 KZN89655.1 - 0.12 12.7 0.2 0.23 11.8 0.2 1.4 1 0 0 1 1 1 0 Putative inner membrane exporter, YdcZ DUF3716 PF12511.8 KZN89656.1 - 0.0014 18.6 0.6 0.0022 18.0 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) PSD2 PF07624.11 KZN89656.1 - 0.059 13.2 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) FAD_binding_4 PF01565.23 KZN89657.1 - 1.1e-22 80.2 2.6 3.2e-22 78.8 2.3 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KZN89657.1 - 6.9e-09 35.7 0.7 1.5e-08 34.6 0.7 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KZN89657.1 - 0.18 11.1 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding MFS_1 PF07690.16 KZN89658.1 - 0.00049 19.1 32.3 0.002 17.1 31.9 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4131 PF13567.6 KZN89658.1 - 9.6 5.8 12.2 1.2 8.7 3.7 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) EBP PF05241.12 KZN89659.1 - 9.5e-46 155.5 12.1 1.5e-44 151.6 10.4 2.0 1 1 1 2 2 2 2 Emopamil binding protein MFS_1 PF07690.16 KZN89660.1 - 2.4e-32 112.2 34.8 3e-32 111.9 34.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KZN89660.1 - 2.5e-07 30.3 6.3 2.5e-07 30.3 6.3 2.5 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB COesterase PF00135.28 KZN89661.1 - 2.4e-100 336.8 0.0 2.7e-100 336.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KZN89661.1 - 5.9e-08 32.8 0.9 4.7e-07 29.9 0.9 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Flavi_NS2A PF01005.19 KZN89661.1 - 0.099 12.8 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2A Ank_2 PF12796.7 KZN89662.1 - 4e-43 145.9 13.5 3.1e-13 50.1 0.9 7.0 5 2 2 7 7 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN89662.1 - 1.2e-35 121.4 1.8 1.3e-10 41.5 0.0 9.9 6 3 3 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN89662.1 - 4e-28 94.4 6.4 0.0029 18.0 0.0 13.1 13 0 0 13 13 12 3 Ankyrin repeat Ank_5 PF13857.6 KZN89662.1 - 5.5e-21 74.4 6.8 0.00099 19.4 0.1 9.0 5 2 5 10 10 10 5 Ankyrin repeats (many copies) Ank PF00023.30 KZN89662.1 - 1e-18 66.9 18.3 0.0018 18.6 0.1 11.8 10 2 2 12 12 12 4 Ankyrin repeat NACHT PF05729.12 KZN89662.1 - 3.3e-11 43.4 0.0 9.6e-11 41.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KZN89662.1 - 2.3e-07 31.1 0.1 1.1e-06 29.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KZN89662.1 - 2.5e-07 31.2 0.0 1.3e-06 28.9 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT_N PF17100.5 KZN89662.1 - 0.00011 22.2 0.2 0.0003 20.7 0.2 1.8 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase AAA_19 PF13245.6 KZN89662.1 - 0.0023 18.3 0.0 0.021 15.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 KZN89662.1 - 0.0046 16.2 1.2 2.6 7.2 0.6 2.9 2 1 0 3 3 3 2 KAP family P-loop domain AAA PF00004.29 KZN89662.1 - 0.0061 17.0 0.2 0.04 14.3 0.2 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KZN89662.1 - 0.018 15.4 0.1 0.094 13.1 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 KZN89662.1 - 0.041 13.6 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Bac_A_amyl_C PF18612.1 KZN89662.1 - 0.066 13.0 0.2 11 5.9 0.0 3.7 4 0 0 4 4 4 0 Bacterial Alpha amylase C-terminal domain PIF1 PF05970.14 KZN89662.1 - 0.067 12.4 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase DUF2075 PF09848.9 KZN89662.1 - 0.07 12.4 0.0 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 KZN89662.1 - 0.16 12.0 0.0 6.5 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) HTH_32 PF13565.6 KZN89663.1 - 5.8e-10 39.7 2.4 2.3e-07 31.3 0.3 2.1 1 1 1 2 2 2 2 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KZN89663.1 - 0.00016 21.8 0.7 0.00067 19.9 0.1 2.0 2 0 0 2 2 2 1 Transposase HTH_24 PF13412.6 KZN89663.1 - 0.0055 16.2 0.0 0.068 12.7 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_29 PF13551.6 KZN89663.1 - 0.051 13.6 0.3 0.17 12.0 0.1 1.9 2 0 0 2 2 2 0 Winged helix-turn helix HTH_38 PF13936.6 KZN89663.1 - 0.088 12.6 0.5 0.87 9.4 0.3 2.7 3 1 0 3 3 3 0 Helix-turn-helix domain APH PF01636.23 KZN89664.1 - 7.8e-12 45.6 0.0 1.5e-11 44.7 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Sugar_tr PF00083.24 KZN89665.1 - 8.2e-113 377.6 20.8 9.4e-113 377.4 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN89665.1 - 4.7e-23 81.7 39.5 1.7e-15 56.8 14.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily E1-E2_ATPase PF00122.20 KZN89667.1 - 2.8e-36 124.7 14.8 1.8e-30 105.8 0.2 3.1 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KZN89667.1 - 1.2e-27 96.8 5.8 1.2e-27 96.8 5.8 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KZN89667.1 - 1.1e-20 74.9 0.0 3.8e-19 69.8 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KZN89667.1 - 3.1e-17 62.4 0.0 6.2e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KZN89667.1 - 9.1e-17 60.5 0.0 2.4e-16 59.2 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KZN89667.1 - 0.00032 20.5 1.0 0.0017 18.1 1.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RTA1 PF04479.13 KZN89669.1 - 7e-56 189.1 8.1 7e-56 189.1 8.1 1.4 2 0 0 2 2 2 1 RTA1 like protein Lung_7-TM_R PF06814.13 KZN89669.1 - 0.0042 16.4 4.8 0.0042 16.4 4.8 1.9 2 0 0 2 2 2 1 Lung seven transmembrane receptor DUF4131 PF13567.6 KZN89669.1 - 2.7 7.6 6.7 0.26 10.9 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) ADH_zinc_N PF00107.26 KZN89670.1 - 8e-24 84.1 1.2 1.4e-23 83.3 1.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KZN89670.1 - 7.5e-15 56.2 0.1 1.4e-14 55.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KZN89670.1 - 2e-11 43.7 0.0 1.5e-09 37.7 0.0 2.5 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Fungal_trans PF04082.18 KZN89671.1 - 5.4e-13 48.6 0.3 1.3e-12 47.4 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KZN89671.1 - 0.0064 16.9 1.8 0.022 15.2 1.8 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type Sec10 PF07393.11 KZN89671.1 - 0.059 11.8 0.2 0.082 11.3 0.2 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 zf-C2H2_11 PF16622.5 KZN89671.1 - 1.2 9.0 4.5 4 7.3 4.5 1.9 1 0 0 1 1 1 0 zinc-finger C2H2-type Fungal_trans_2 PF11951.8 KZN89672.1 - 5.2e-11 42.0 0.4 4.5e-10 38.9 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN89672.1 - 1.5e-05 25.1 2.6 2.6e-05 24.3 2.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyoxalase PF00903.25 KZN89674.1 - 1e-05 25.8 0.0 0.00012 22.3 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Sacchrp_dh_NADP PF03435.18 KZN89675.1 - 6.8e-12 45.8 0.1 1.5e-11 44.6 0.1 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Sacchrp_dh_C PF16653.5 KZN89675.1 - 0.027 14.6 0.0 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase C-terminal domain adh_short PF00106.25 KZN89675.1 - 0.11 11.9 0.1 0.83 9.1 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase DAO PF01266.24 KZN89676.1 - 7.4e-29 101.4 0.0 8.7e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KZN89676.1 - 1.3e-05 25.4 0.1 3e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KZN89676.1 - 0.0037 16.5 0.0 0.0062 15.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KZN89676.1 - 0.015 14.5 0.0 0.041 13.1 0.0 1.6 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 KZN89676.1 - 0.018 15.1 0.1 0.15 12.1 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KZN89676.1 - 0.021 15.4 0.0 0.07 13.7 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AAT PF03417.16 KZN89677.1 - 5.9e-47 160.2 0.0 7.2e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DIOX_N PF14226.6 KZN89678.1 - 2.2e-16 60.7 0.1 3.3e-16 60.1 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KZN89678.1 - 1.4e-15 57.6 0.2 4.2e-15 56.1 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Condensation PF00668.20 KZN89679.1 - 2.3e-274 910.0 2.8 1.3e-98 330.7 1.0 4.6 5 0 0 5 5 5 4 Condensation domain AMP-binding PF00501.28 KZN89679.1 - 5e-245 812.7 0.0 9.6e-86 288.0 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme PP-binding PF00550.25 KZN89679.1 - 1.9e-43 146.7 0.1 6.1e-14 52.1 0.1 4.0 3 0 0 3 3 3 3 Phosphopantetheine attachment site Thioesterase PF00975.20 KZN89679.1 - 7.4e-29 101.5 0.0 1.8e-28 100.3 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain AMP-binding_C PF13193.6 KZN89679.1 - 1e-25 90.5 0.0 9e-08 33.0 0.0 3.9 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain LpxD PF04613.14 KZN89679.1 - 0.02 14.6 0.4 2.7 7.8 0.1 3.0 3 0 0 3 3 3 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Abhydrolase_6 PF12697.7 KZN89679.1 - 0.036 14.7 0.0 0.15 12.6 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family RHH_5 PF07878.11 KZN89679.1 - 0.071 13.0 0.0 0.23 11.3 0.0 1.9 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 GH3 PF03321.13 KZN89679.1 - 0.076 11.9 0.7 1.8 7.3 0.0 3.2 4 0 0 4 4 4 0 GH3 auxin-responsive promoter AATase PF07247.12 KZN89679.1 - 0.12 10.9 0.1 0.72 8.3 0.1 2.2 2 0 0 2 2 2 0 Alcohol acetyltransferase Peptidase_S41 PF03572.18 KZN89680.1 - 3.7e-09 36.3 0.0 8.3e-09 35.2 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 Methyltransf_32 PF13679.6 KZN89681.1 - 2.3e-21 76.4 0.0 5.4e-21 75.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain DUF1180 PF06679.12 KZN89683.1 - 1 9.8 5.1 1.2 9.5 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Glyco_transf_54 PF04666.13 KZN89686.1 - 1.3e-10 40.7 0.0 1.4e-08 34.0 0.0 2.8 2 1 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DMT_YdcZ PF04657.13 KZN89686.1 - 0.12 12.7 0.2 0.23 11.8 0.2 1.4 1 0 0 1 1 1 0 Putative inner membrane exporter, YdcZ DUF3716 PF12511.8 KZN89687.1 - 0.0014 18.6 0.6 0.0022 18.0 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) PSD2 PF07624.11 KZN89687.1 - 0.059 13.2 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) FAD_binding_4 PF01565.23 KZN89688.1 - 1.1e-22 80.2 2.6 3.2e-22 78.8 2.3 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KZN89688.1 - 6.9e-09 35.7 0.7 1.5e-08 34.6 0.7 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KZN89688.1 - 0.18 11.1 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding MFS_1 PF07690.16 KZN89689.1 - 0.00049 19.1 32.3 0.002 17.1 31.9 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4131 PF13567.6 KZN89689.1 - 9.6 5.8 12.2 1.2 8.7 3.7 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) EBP PF05241.12 KZN89690.1 - 9.5e-46 155.5 12.1 1.5e-44 151.6 10.4 2.0 1 1 1 2 2 2 2 Emopamil binding protein MFS_1 PF07690.16 KZN89691.1 - 2.4e-32 112.2 34.8 3e-32 111.9 34.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KZN89691.1 - 2.5e-07 30.3 6.3 2.5e-07 30.3 6.3 2.5 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB COesterase PF00135.28 KZN89692.1 - 2.4e-100 336.8 0.0 2.7e-100 336.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KZN89692.1 - 5.9e-08 32.8 0.9 4.7e-07 29.9 0.9 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Flavi_NS2A PF01005.19 KZN89692.1 - 0.099 12.8 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2A Ank_2 PF12796.7 KZN89693.1 - 4e-43 145.9 13.5 3.1e-13 50.1 0.9 7.0 5 2 2 7 7 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN89693.1 - 1.2e-35 121.4 1.8 1.3e-10 41.5 0.0 9.9 6 3 3 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN89693.1 - 4e-28 94.4 6.4 0.0029 18.0 0.0 13.1 13 0 0 13 13 12 3 Ankyrin repeat Ank_5 PF13857.6 KZN89693.1 - 5.5e-21 74.4 6.8 0.00099 19.4 0.1 9.0 5 2 5 10 10 10 5 Ankyrin repeats (many copies) Ank PF00023.30 KZN89693.1 - 1e-18 66.9 18.3 0.0018 18.6 0.1 11.8 10 2 2 12 12 12 4 Ankyrin repeat NACHT PF05729.12 KZN89693.1 - 3.3e-11 43.4 0.0 9.6e-11 41.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KZN89693.1 - 2.3e-07 31.1 0.1 1.1e-06 29.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KZN89693.1 - 2.5e-07 31.2 0.0 1.3e-06 28.9 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT_N PF17100.5 KZN89693.1 - 0.00011 22.2 0.2 0.0003 20.7 0.2 1.8 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase AAA_19 PF13245.6 KZN89693.1 - 0.0023 18.3 0.0 0.021 15.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 KZN89693.1 - 0.0046 16.2 1.2 2.6 7.2 0.6 2.9 2 1 0 3 3 3 2 KAP family P-loop domain AAA PF00004.29 KZN89693.1 - 0.0061 17.0 0.2 0.04 14.3 0.2 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KZN89693.1 - 0.018 15.4 0.1 0.094 13.1 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 KZN89693.1 - 0.041 13.6 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Bac_A_amyl_C PF18612.1 KZN89693.1 - 0.066 13.0 0.2 11 5.9 0.0 3.7 4 0 0 4 4 4 0 Bacterial Alpha amylase C-terminal domain PIF1 PF05970.14 KZN89693.1 - 0.067 12.4 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase DUF2075 PF09848.9 KZN89693.1 - 0.07 12.4 0.0 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 KZN89693.1 - 0.16 12.0 0.0 6.5 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) HTH_32 PF13565.6 KZN89694.1 - 5.8e-10 39.7 2.4 2.3e-07 31.3 0.3 2.1 1 1 1 2 2 2 2 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KZN89694.1 - 0.00016 21.8 0.7 0.00067 19.9 0.1 2.0 2 0 0 2 2 2 1 Transposase HTH_24 PF13412.6 KZN89694.1 - 0.0055 16.2 0.0 0.068 12.7 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_29 PF13551.6 KZN89694.1 - 0.051 13.6 0.3 0.17 12.0 0.1 1.9 2 0 0 2 2 2 0 Winged helix-turn helix HTH_38 PF13936.6 KZN89694.1 - 0.088 12.6 0.5 0.87 9.4 0.3 2.7 3 1 0 3 3 3 0 Helix-turn-helix domain APH PF01636.23 KZN89695.1 - 7.8e-12 45.6 0.0 1.5e-11 44.7 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Sugar_tr PF00083.24 KZN89696.1 - 8.2e-113 377.6 20.8 9.4e-113 377.4 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN89696.1 - 4.7e-23 81.7 39.5 1.7e-15 56.8 14.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily E1-E2_ATPase PF00122.20 KZN89698.1 - 2.8e-36 124.7 14.8 1.8e-30 105.8 0.2 3.1 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KZN89698.1 - 1.2e-27 96.8 5.8 1.2e-27 96.8 5.8 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KZN89698.1 - 1.1e-20 74.9 0.0 3.8e-19 69.8 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KZN89698.1 - 3.1e-17 62.4 0.0 6.2e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KZN89698.1 - 9.1e-17 60.5 0.0 2.4e-16 59.2 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KZN89698.1 - 0.00032 20.5 1.0 0.0017 18.1 1.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RTA1 PF04479.13 KZN89700.1 - 7e-56 189.1 8.1 7e-56 189.1 8.1 1.4 2 0 0 2 2 2 1 RTA1 like protein Lung_7-TM_R PF06814.13 KZN89700.1 - 0.0042 16.4 4.8 0.0042 16.4 4.8 1.9 2 0 0 2 2 2 1 Lung seven transmembrane receptor DUF4131 PF13567.6 KZN89700.1 - 2.7 7.6 6.7 0.26 10.9 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) ADH_zinc_N PF00107.26 KZN89701.1 - 8e-24 84.1 1.2 1.4e-23 83.3 1.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KZN89701.1 - 7.5e-15 56.2 0.1 1.4e-14 55.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KZN89701.1 - 2e-11 43.7 0.0 1.5e-09 37.7 0.0 2.5 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Fungal_trans PF04082.18 KZN89702.1 - 5.4e-13 48.6 0.3 1.3e-12 47.4 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KZN89702.1 - 0.0064 16.9 1.8 0.022 15.2 1.8 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type Sec10 PF07393.11 KZN89702.1 - 0.059 11.8 0.2 0.082 11.3 0.2 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 zf-C2H2_11 PF16622.5 KZN89702.1 - 1.2 9.0 4.5 4 7.3 4.5 1.9 1 0 0 1 1 1 0 zinc-finger C2H2-type Fungal_trans_2 PF11951.8 KZN89703.1 - 5.2e-11 42.0 0.4 4.5e-10 38.9 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN89703.1 - 1.5e-05 25.1 2.6 2.6e-05 24.3 2.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.29 KZN89705.1 - 8.9e-47 159.1 0.1 1.9e-46 158.1 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KZN89705.1 - 1.4e-23 83.4 0.0 4.1e-23 81.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KZN89705.1 - 6.7e-22 77.5 1.9 2.1e-21 75.9 1.9 2.0 1 0 0 1 1 1 1 DBP10CT (NUC160) domain RPA_C PF08784.11 KZN89706.1 - 1.2e-20 74.1 0.0 3e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KZN89706.1 - 0.00029 20.8 0.3 0.00082 19.3 0.3 1.8 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 KZN89706.1 - 0.077 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 MatE PF01554.18 KZN89707.1 - 1.5e-57 193.8 26.8 2.6e-34 118.2 9.2 2.5 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KZN89707.1 - 1.5e-05 25.1 9.3 1.5e-05 25.1 9.3 4.0 2 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain DUF202 PF02656.15 KZN89708.1 - 8.7e-17 61.3 3.4 1.1e-16 61.0 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) NUDIX PF00293.28 KZN89709.1 - 1.6e-26 92.9 0.0 2.3e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain FMO-like PF00743.19 KZN89710.1 - 3.3e-34 118.2 0.0 1.2e-19 70.1 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KZN89710.1 - 2.1e-14 53.5 1.1 3.1e-11 43.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KZN89710.1 - 1.1e-11 44.5 0.0 2.7e-11 43.3 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KZN89710.1 - 1.8e-07 31.3 0.5 8.6e-06 25.8 0.3 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KZN89710.1 - 1.2e-06 28.0 1.2 0.00052 19.2 0.0 3.1 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KZN89710.1 - 1.2e-06 28.4 3.9 0.0003 20.5 3.4 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KZN89710.1 - 2e-06 27.9 0.8 4.9e-06 26.7 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KZN89710.1 - 5.1e-05 23.8 1.6 0.011 16.3 0.7 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KZN89710.1 - 0.0007 19.3 0.1 0.14 11.8 0.0 2.9 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 KZN89710.1 - 0.0016 17.8 1.9 0.0029 16.9 1.9 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KZN89710.1 - 0.0068 15.7 0.1 0.025 13.9 0.1 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KZN89710.1 - 0.012 15.0 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 KZN89710.1 - 0.02 14.1 2.0 0.021 14.0 0.9 1.5 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.20 KZN89710.1 - 0.027 14.5 1.7 0.06 13.4 0.6 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 KZN89710.1 - 0.03 13.0 3.5 0.054 12.2 3.5 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 KZN89710.1 - 0.036 13.1 0.0 0.096 11.8 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain NAD_binding_2 PF03446.15 KZN89710.1 - 0.055 13.6 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KZN89710.1 - 0.12 12.3 2.4 0.2 11.5 2.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KZN89710.1 - 0.21 10.8 3.5 1.9 7.7 3.7 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KZN89710.1 - 2.8 6.9 3.8 5.1 6.1 3.8 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A zf-C2H2 PF00096.26 KZN89711.1 - 7.5e-11 41.9 24.0 0.00014 22.1 5.0 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KZN89711.1 - 8.8e-09 35.5 19.9 0.00069 20.3 2.6 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KZN89711.1 - 4.9e-08 33.0 16.2 0.00011 22.4 1.1 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-met PF12874.7 KZN89711.1 - 5.4e-06 26.6 15.6 0.029 14.8 1.4 3.7 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KZN89711.1 - 3.7e-05 23.9 11.8 0.0048 17.1 1.6 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KZN89711.1 - 0.00042 20.6 5.2 0.00042 20.6 5.2 2.2 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KZN89711.1 - 0.013 15.5 12.6 0.61 10.2 2.4 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Prok-RING_1 PF14446.6 KZN89711.1 - 0.2 11.6 6.2 20 5.2 0.1 3.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 tRNA-synt_1g PF09334.11 KZN89711.1 - 0.3 9.8 0.8 0.41 9.3 0.8 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (M) zf-BED PF02892.15 KZN89711.1 - 0.72 9.9 15.2 0.084 12.9 3.9 3.1 2 1 1 3 3 3 0 BED zinc finger zinc-ribbons_6 PF07191.12 KZN89711.1 - 2.5 8.1 7.3 31 4.6 0.6 2.5 1 1 1 2 2 2 0 zinc-ribbons Zn-ribbon_8 PF09723.10 KZN89711.1 - 3.2 7.9 11.1 3.9 7.7 0.1 3.2 2 1 1 3 3 3 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 KZN89711.1 - 3.6 7.6 16.9 2.8 8.0 0.6 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 KZN89711.1 - 5.3 7.4 15.8 8 6.9 2.6 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 KZN89711.1 - 6 6.6 9.1 25 4.5 0.1 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-RING_2 PF13639.6 KZN89711.1 - 9.8 6.6 9.7 62 4.1 0.2 3.2 2 1 1 3 3 3 0 Ring finger domain Pkinase PF00069.25 KZN89712.1 - 1.1e-23 84.0 0.0 1.6e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 KZN89712.1 - 5.5e-10 38.6 4.8 0.25 11.7 0.0 6.8 6 0 0 6 6 6 3 HEAT repeat WD40 PF00400.32 KZN89712.1 - 4.3e-06 27.3 0.1 4.3e-06 27.3 0.1 5.2 6 0 0 6 6 6 2 WD domain, G-beta repeat HEAT_2 PF13646.6 KZN89712.1 - 2.9e-05 24.4 0.3 11 6.5 0.3 4.4 2 2 1 4 4 4 2 HEAT repeats Pkinase_Tyr PF07714.17 KZN89712.1 - 3.7e-05 23.1 0.0 7.4e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.6 KZN89712.1 - 0.00011 22.6 0.4 0.022 15.3 0.2 3.8 3 0 0 3 3 3 1 HEAT-like repeat Tti2 PF10521.9 KZN89712.1 - 0.013 15.0 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 Tti2 family Cnd1 PF12717.7 KZN89712.1 - 0.052 13.6 1.1 0.54 10.3 0.0 2.5 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Ge1_WD40 PF16529.5 KZN89712.1 - 0.2 10.6 0.1 0.64 8.9 0.0 1.8 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DENN PF02141.21 KZN89713.1 - 7e-40 137.0 0.1 1.3e-39 136.1 0.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KZN89713.1 - 1.4e-05 25.8 0.1 8.4e-05 23.2 0.0 2.4 2 0 0 2 2 2 1 uDENN domain PqqD PF05402.12 KZN89713.1 - 0.048 14.0 0.4 1.3 9.4 0.0 3.0 3 0 0 3 3 3 0 Coenzyme PQQ synthesis protein D (PqqD) Cnn_1N PF07989.11 KZN89713.1 - 0.36 11.0 11.3 0.18 12.0 2.7 3.3 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Elongin_A PF06881.11 KZN89713.1 - 0.58 10.7 11.9 0.023 15.2 4.6 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A CENP-F_leu_zip PF10473.9 KZN89713.1 - 5.9 6.9 23.5 0.04 13.9 6.3 2.9 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BRE1 PF08647.11 KZN89713.1 - 7 6.8 19.3 3.7 7.7 6.5 3.7 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase adh_short_C2 PF13561.6 KZN89714.1 - 2.1e-54 184.6 1.6 2.6e-54 184.3 1.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN89714.1 - 2.3e-44 151.2 0.8 2.9e-44 150.9 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN89714.1 - 2.3e-08 34.2 0.4 6.7e-08 32.6 0.4 1.7 1 1 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 KZN89714.1 - 0.14 12.9 0.0 0.32 11.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RabGAP-TBC PF00566.18 KZN89715.1 - 2.4e-42 145.0 0.0 3e-40 138.2 0.0 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Nsp1_C PF05064.13 KZN89717.1 - 0.028 14.2 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 Nsp1-like C-terminal region Zn_clus PF00172.18 KZN89718.1 - 4.9e-10 39.4 8.9 7.6e-10 38.8 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN89718.1 - 2.9e-09 36.3 0.0 4.6e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1451 PF07295.11 KZN89718.1 - 0.74 9.8 2.6 1.8 8.6 2.6 1.6 1 0 0 1 1 1 0 Zinc-ribbon containing domain Ost4 PF10215.9 KZN89719.1 - 1.8e-19 69.3 1.2 2.2e-19 68.9 1.2 1.2 1 0 0 1 1 1 1 Oligosaccaryltransferase FOXP-CC PF16159.5 KZN89720.1 - 0.026 15.1 3.1 6.3 7.5 0.2 3.0 1 1 1 2 2 2 0 FOXP coiled-coil domain Ribosomal_L26 PF16906.5 KZN89721.1 - 1.9e-35 121.2 1.4 2.3e-35 120.9 1.4 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KZN89721.1 - 2.6e-05 24.0 0.3 5.7e-05 22.9 0.3 1.6 1 0 0 1 1 1 1 KOW motif Synaptobrevin PF00957.21 KZN89722.1 - 1.1e-31 108.4 0.0 1.5e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KZN89722.1 - 3e-27 94.5 0.1 5.4e-27 93.7 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Toxin_36 PF10550.9 KZN89723.1 - 7.4 8.2 6.2 28 6.4 2.6 3.0 2 0 0 2 2 2 0 Conantokin-G mollusc-toxin TPR_10 PF13374.6 KZN89724.1 - 1.3e-51 171.1 0.1 3.6e-11 42.6 0.0 8.5 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.6 KZN89724.1 - 4.6e-41 139.0 2.8 7.1e-12 45.5 0.1 7.1 3 3 3 7 7 7 7 Tetratricopeptide repeat TPR_MalT PF17874.1 KZN89724.1 - 6.5e-10 38.9 3.3 2e-07 30.7 0.9 3.0 1 1 0 2 2 2 2 MalT-like TPR region TPR_7 PF13176.6 KZN89724.1 - 1.6e-09 37.1 10.7 0.66 10.1 0.0 7.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 KZN89724.1 - 6.4e-09 35.3 3.4 19 5.7 0.0 7.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 KZN89724.1 - 1.3e-07 31.2 4.8 1.1 9.7 0.1 6.1 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KZN89724.1 - 4.3e-05 24.0 2.7 0.61 10.6 0.1 4.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KZN89724.1 - 0.00013 21.6 0.9 44 4.1 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 KZN89724.1 - 0.00022 21.8 3.4 12 6.6 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KZN89724.1 - 0.00025 21.6 2.5 1.4 9.9 0.0 5.3 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 KZN89724.1 - 0.0041 17.6 0.1 5.3 8.0 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat zf-Di19 PF05605.12 KZN89724.1 - 0.0042 17.3 6.2 4.7 7.6 0.5 3.6 2 1 1 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KZN89724.1 - 0.0079 16.6 1.6 0.074 13.5 0.1 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KZN89724.1 - 0.013 16.0 8.7 0.85 10.2 0.1 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KZN89724.1 - 0.054 14.4 12.6 3.6 8.7 0.1 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KZN89724.1 - 0.056 13.8 2.9 1.9 8.8 0.9 3.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) PPR PF01535.20 KZN89724.1 - 0.061 13.6 0.4 8.3 6.9 0.0 4.3 5 0 0 5 5 5 0 PPR repeat zf-Sec23_Sec24 PF04810.15 KZN89724.1 - 0.075 13.1 5.8 0.22 11.6 0.5 3.1 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger UL42 PF17638.2 KZN89724.1 - 0.11 12.5 1.0 0.31 11.0 1.0 1.7 1 0 0 1 1 1 0 HCMV UL42 Vps36-NZF-N PF16988.5 KZN89724.1 - 0.15 11.5 0.5 0.49 9.8 0.0 2.1 2 0 0 2 2 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain TPR_6 PF13174.6 KZN89724.1 - 0.25 12.1 5.5 15 6.5 0.2 5.2 7 0 0 7 7 4 0 Tetratricopeptide repeat OrsD PF12013.8 KZN89724.1 - 0.85 10.1 3.2 2.1 8.8 0.4 3.0 3 1 0 3 3 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D GTP_CH_N PF12471.8 KZN89726.1 - 0.18 11.5 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 GTP cyclohydrolase N terminal CPSase_L_D2 PF02786.17 KZN89728.1 - 4.8e-114 379.1 0.2 9.2e-84 280.2 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.28 KZN89728.1 - 3.7e-47 160.6 0.0 2.5e-46 157.8 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 KZN89728.1 - 1.1e-46 157.8 0.0 2.6e-46 156.6 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 KZN89728.1 - 7.7e-46 155.8 0.0 1.6e-45 154.7 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 KZN89728.1 - 9.1e-38 129.3 0.0 2e-37 128.2 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 KZN89728.1 - 1e-29 103.7 0.0 2.3e-29 102.5 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 KZN89728.1 - 1.4e-19 70.1 0.0 7.6e-19 67.7 0.0 2.4 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.13 KZN89728.1 - 3.7e-17 62.6 0.9 4.3e-08 32.9 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KZN89728.1 - 4.1e-15 55.8 0.1 9.1e-08 31.9 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KZN89728.1 - 1.6e-09 37.6 0.0 0.00016 21.4 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 KZN89728.1 - 7.9e-06 25.8 0.1 0.0005 19.9 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.14 KZN89728.1 - 6.4e-05 23.1 0.6 0.38 10.8 0.1 3.2 3 0 0 3 3 3 2 ATP-grasp domain DJ-1_PfpI PF01965.24 KZN89728.1 - 0.0015 18.3 0.6 0.65 9.8 0.0 4.5 5 0 0 5 5 5 1 DJ-1/PfpI family RimK PF08443.11 KZN89728.1 - 0.002 17.7 0.0 2 8.0 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain MFS_1 PF07690.16 KZN89729.1 - 4.1e-37 127.9 22.6 4.1e-37 127.9 22.6 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily AMP-binding PF00501.28 KZN89730.1 - 5.7e-80 269.0 0.0 6.7e-80 268.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KZN89730.1 - 5.8e-11 43.2 0.7 1.7e-10 41.7 0.5 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.6 KZN89731.1 - 2.6e-07 30.7 0.0 3.2e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KZN89731.1 - 0.00013 21.5 0.0 0.00016 21.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KZN89731.1 - 0.0023 17.1 0.0 0.012 14.8 0.0 2.0 2 1 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 KZN89731.1 - 0.043 12.9 0.0 0.1 11.7 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Exo84_C PF16528.5 KZN89732.1 - 1.3e-66 224.3 1.8 1.4e-66 224.2 0.0 1.8 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 KZN89732.1 - 1.5e-18 66.6 1.4 3.3e-18 65.6 1.4 1.6 1 0 0 1 1 1 1 Vps51/Vps67 DUF2594 PF10769.9 KZN89732.1 - 0.12 12.5 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2594) SKA2 PF16740.5 KZN89732.1 - 0.77 9.6 3.8 0.49 10.2 1.0 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Apolipoprotein PF01442.18 KZN89732.1 - 0.86 9.4 6.1 6 6.7 0.2 2.3 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain HIP1_clath_bdg PF16515.5 KZN89732.1 - 2.1 9.0 6.5 0.69 10.5 2.7 2.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 MAS20 PF02064.15 KZN89733.1 - 1e-42 145.3 0.3 1.2e-42 145.1 0.3 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor Glyco_hydro_72 PF03198.14 KZN89734.1 - 1.5e-126 422.0 2.3 1.9e-126 421.6 2.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KZN89734.1 - 0.00029 20.4 0.1 0.018 14.5 0.1 2.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AF-4 PF05110.13 KZN89734.1 - 7.8 4.4 9.0 11 4.0 9.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein AMP-binding PF00501.28 KZN89735.1 - 8.2e-89 298.1 0.0 1e-88 297.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KZN89735.1 - 1.6e-16 61.0 2.6 3.9e-16 59.8 2.6 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain F-box-like PF12937.7 KZN89736.1 - 3.1e-09 36.6 0.1 7.9e-09 35.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN89736.1 - 1.3e-07 31.3 0.3 3.3e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KZN89736.1 - 0.026 14.4 0.0 0.064 13.1 0.0 1.6 1 0 0 1 1 1 0 F-box Hira PF07569.11 KZN89736.1 - 0.037 13.8 0.0 0.086 12.5 0.0 1.6 1 0 0 1 1 1 0 TUP1-like enhancer of split UIM PF02809.20 KZN89736.1 - 5.7 7.1 12.1 2.6 8.2 0.3 3.5 3 0 0 3 3 3 0 Ubiquitin interaction motif Tyrosinase PF00264.20 KZN89738.1 - 5.9e-50 170.6 2.4 1e-49 169.8 2.4 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KZN89738.1 - 1.2e-19 71.2 0.0 2.3e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Tyosinase C-terminal domain Gal-bind_lectin PF00337.22 KZN89738.1 - 4.1e-08 32.9 0.0 1.1e-07 31.5 0.0 1.7 2 0 0 2 2 2 1 Galactoside-binding lectin Mre11_DNA_bind PF04152.14 KZN89739.1 - 1.2e-56 191.6 1.3 1.2e-56 191.6 1.3 2.1 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KZN89739.1 - 5.8e-14 53.1 1.8 7.4e-14 52.7 1.0 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KZN89739.1 - 0.0014 18.9 0.0 0.0096 16.1 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain AtuA PF07287.11 KZN89740.1 - 2.9e-125 417.7 0.0 3.4e-125 417.4 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Metallophos PF00149.28 KZN89742.1 - 5.4e-12 46.6 0.0 7.8e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KZN89742.1 - 1.4e-11 44.9 0.0 7.7e-07 29.5 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain 2-Hacid_dh_C PF02826.19 KZN89743.1 - 8.3e-54 181.6 0.0 1.1e-53 181.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KZN89743.1 - 2e-22 79.3 0.0 2.3e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KZN89743.1 - 5.2e-05 23.5 0.0 0.00015 22.0 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Hydrolase_4 PF12146.8 KZN89744.1 - 1.5e-05 24.4 0.0 0.0027 17.0 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KZN89744.1 - 0.00067 19.2 0.1 0.15 11.5 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family LIP PF03583.14 KZN89744.1 - 0.0027 17.1 0.3 0.41 9.9 0.3 2.2 2 0 0 2 2 2 2 Secretory lipase Abhydrolase_6 PF12697.7 KZN89744.1 - 0.0059 17.2 0.1 0.009 16.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KZN89744.1 - 0.0094 15.6 0.0 0.073 12.6 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Chlorophyllase2 PF12740.7 KZN89744.1 - 0.024 13.6 0.0 0.057 12.3 0.0 1.6 1 1 0 1 1 1 0 Chlorophyllase enzyme DUF4274 PF14096.6 KZN89745.1 - 0.031 14.2 0.0 0.08 12.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4274) ATP_synt_H PF05493.13 KZN89745.1 - 2 8.9 15.9 0.044 14.2 3.7 2.5 2 0 0 2 2 2 0 ATP synthase subunit H Methyltransf_31 PF13847.6 KZN89746.1 - 5.9e-18 65.1 0.0 8.8e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN89746.1 - 9.3e-17 61.5 0.1 1.6e-16 60.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN89746.1 - 3.2e-16 59.8 0.1 5.7e-16 59.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN89746.1 - 3.9e-15 56.1 0.0 5.6e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KZN89746.1 - 6.3e-13 48.6 0.0 7.8e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KZN89746.1 - 1.5e-09 38.5 0.0 3.2e-09 37.4 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KZN89746.1 - 2.8e-08 33.4 0.0 7.7e-08 32.0 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KZN89746.1 - 1.2e-07 31.5 0.0 2.4e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KZN89746.1 - 2.5e-06 27.3 0.0 3.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.11 KZN89746.1 - 3e-06 26.4 0.0 4.3e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 KZN89746.1 - 5.1e-05 23.2 0.0 8.2e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 KZN89746.1 - 0.00013 21.7 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.10 KZN89746.1 - 0.00019 21.1 0.0 0.00026 20.6 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.19 KZN89746.1 - 0.00022 21.0 0.1 0.00046 20.0 0.1 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TPMT PF05724.11 KZN89746.1 - 0.00096 18.9 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.6 KZN89746.1 - 0.0042 17.1 0.0 0.006 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KZN89746.1 - 0.012 15.5 0.0 0.2 11.5 0.0 2.1 1 1 0 1 1 1 0 Hypothetical methyltransferase PrmA PF06325.13 KZN89746.1 - 0.016 14.6 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KZN89746.1 - 0.02 14.4 0.0 0.075 12.5 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase NodS PF05401.11 KZN89746.1 - 0.05 13.2 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Ribosomal_L7Ae PF01248.26 KZN89748.1 - 7.6e-25 86.5 0.0 9.5e-25 86.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KZN89748.1 - 2e-05 24.7 0.0 2.4e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 KZN89748.1 - 4.2e-05 23.3 0.0 5.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain Dus PF01207.17 KZN89749.1 - 1.3e-58 198.5 0.0 1.9e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 KZN89749.1 - 0.0053 16.0 0.0 0.0083 15.4 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase ANAPC4_WD40 PF12894.7 KZN89750.1 - 8.2e-05 22.8 0.3 2.5 8.5 0.1 4.5 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KZN89750.1 - 0.0019 18.1 0.7 0.2 11.6 0.2 3.3 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat WD40 PF00400.32 KZN89750.1 - 0.25 12.3 10.7 7.4 7.6 0.2 5.5 5 1 1 6 6 6 0 WD domain, G-beta repeat ERG4_ERG24 PF01222.17 KZN89752.1 - 9.9e-77 258.5 7.6 1.2e-76 258.2 7.6 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 KZN89752.1 - 0.00028 21.2 0.0 0.0012 19.2 0.0 2.1 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.12 KZN89752.1 - 0.00063 19.3 2.8 0.00063 19.3 2.8 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF1295) DUF5592 PF17332.2 KZN89752.1 - 0.068 13.7 0.4 0.76 10.4 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5592) p450 PF00067.22 KZN89753.1 - 1.6e-22 79.9 0.0 6.2e-21 74.7 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 MBOAT_2 PF13813.6 KZN89754.1 - 4e-25 87.9 0.3 9.3e-25 86.7 0.3 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family p450 PF00067.22 KZN89755.1 - 2.4e-31 109.0 0.0 3.5e-30 105.2 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KZN89756.1 - 3.9e-37 128.1 0.0 5.1e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ERG4_ERG24 PF01222.17 KZN89757.1 - 8.7e-142 472.9 11.9 9.7e-142 472.7 11.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KZN89757.1 - 0.00015 21.3 0.2 0.00015 21.3 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) ORC6 PF05460.13 KZN89758.1 - 0.82 8.9 3.9 0.83 8.9 3.9 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Hamartin PF04388.12 KZN89758.1 - 2.1 6.9 4.5 2.1 6.9 4.5 1.0 1 0 0 1 1 1 0 Hamartin protein p450 PF00067.22 KZN89759.1 - 1e-74 252.0 0.0 1.3e-74 251.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4297 PF14130.6 KZN89759.1 - 0.18 11.9 0.4 0.29 11.2 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4297) Aldedh PF00171.22 KZN89760.1 - 6.9e-46 156.7 1.9 1.4e-36 126.1 0.2 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family MFS_1 PF07690.16 KZN89761.1 - 1.2e-31 109.9 29.0 1.6e-31 109.5 29.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KZN89761.1 - 1.7e-06 26.8 6.2 1.7e-06 26.8 6.2 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.25 KZN89762.1 - 1.9e-36 125.3 0.0 2.6e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN89762.1 - 6.1e-29 101.2 0.0 8e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN89762.1 - 0.0007 19.5 0.2 0.011 15.6 0.2 2.2 1 1 0 1 1 1 1 KR domain Ldh_1_N PF00056.23 KZN89762.1 - 0.14 12.3 0.1 2.6 8.1 0.1 2.2 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Epimerase PF01370.21 KZN89762.1 - 0.16 11.4 0.1 0.31 10.4 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DFP PF04127.15 KZN89762.1 - 0.2 11.4 0.0 0.3 10.9 0.0 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein CMD PF02627.20 KZN89763.1 - 1.2e-19 70.2 0.0 1.8e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family DUF3967 PF13152.6 KZN89763.1 - 0.042 13.6 0.8 0.088 12.6 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3967) DUF2827 PF10933.8 KZN89763.1 - 0.24 10.0 0.0 0.31 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2827) NAD_binding_2 PF03446.15 KZN89764.1 - 5.9e-39 133.8 0.0 8.1e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KZN89764.1 - 5.5e-23 81.5 0.0 8.2e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.15 KZN89764.1 - 0.0026 16.8 0.0 0.0037 16.3 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.17 KZN89764.1 - 0.0059 17.2 0.0 0.012 16.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Lactamase_B PF00753.27 KZN89765.1 - 1.3e-06 28.6 0.6 2.5e-06 27.6 0.6 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KZN89765.1 - 0.022 14.3 0.6 0.059 12.9 0.1 1.8 2 0 0 2 2 2 0 Beta-lactamase superfamily domain MaoC_dehydratas PF01575.19 KZN89765.1 - 0.029 13.9 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain Abhydrolase_1 PF00561.20 KZN89766.1 - 4.7e-23 82.1 0.0 3.9e-22 79.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KZN89766.1 - 3.5e-11 44.1 2.4 4.3e-11 43.8 2.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KZN89766.1 - 2.4e-07 30.3 0.0 1.5e-06 27.7 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KZN89766.1 - 1.4e-06 28.3 0.0 4.7e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein Ndr PF03096.14 KZN89766.1 - 0.011 14.4 0.0 0.09 11.5 0.0 1.9 2 0 0 2 2 2 0 Ndr family COesterase PF00135.28 KZN89767.1 - 4.2e-58 197.5 0.0 1.9e-57 195.3 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KZN89767.1 - 3.3e-08 33.6 0.1 2.8e-07 30.6 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KZN89767.1 - 0.00044 20.9 0.1 0.0007 20.3 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KZN89767.1 - 0.0012 18.6 0.1 0.0038 16.9 0.1 1.7 1 1 0 1 1 1 1 Putative esterase HTH_24 PF13412.6 KZN89767.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Say1_Mug180 PF10340.9 KZN89767.1 - 0.13 11.0 0.1 0.74 8.6 0.0 1.9 2 0 0 2 2 2 0 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 KZN89767.1 - 0.17 11.7 0.6 0.31 10.8 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase adh_short PF00106.25 KZN89768.1 - 1.7e-29 102.7 0.0 2.2e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN89768.1 - 2.9e-24 85.9 0.0 4.1e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN89768.1 - 1.4e-05 25.1 0.2 0.00056 19.9 0.1 2.1 2 0 0 2 2 2 1 KR domain YAcAr PF10686.9 KZN89768.1 - 0.026 14.5 0.1 0.049 13.6 0.1 1.4 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family 2-Hacid_dh_C PF02826.19 KZN89768.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KZN89769.1 - 1.1e-48 166.3 0.0 1.5e-48 165.8 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KZN89769.1 - 4.4e-08 32.7 0.1 1.3e-06 27.8 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KZN89769.1 - 1.1e-06 27.6 0.0 3.8e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KZN89769.1 - 2.1e-06 27.6 0.2 0.0043 16.7 0.1 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KZN89769.1 - 6.2e-06 26.7 0.0 0.062 13.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN89769.1 - 8.6e-06 25.9 0.3 2.5e-05 24.4 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KZN89769.1 - 3.1e-05 23.4 1.1 0.0013 18.1 0.0 2.7 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KZN89769.1 - 0.00071 18.8 0.7 0.0027 16.9 0.5 1.8 1 1 1 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KZN89769.1 - 0.00099 18.3 0.1 0.0022 17.1 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KZN89769.1 - 0.0012 18.2 0.2 0.019 14.2 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 KZN89769.1 - 0.012 14.2 0.0 0.018 13.6 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.6 KZN89769.1 - 0.016 15.2 0.1 2.4 8.1 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 KZN89769.1 - 0.022 14.3 0.0 0.092 12.3 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.17 KZN89769.1 - 0.041 13.1 0.1 0.066 12.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KZN89769.1 - 0.062 12.4 0.0 0.09 11.8 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KZN89769.1 - 0.085 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KZN89769.1 - 0.12 12.1 0.1 0.23 11.1 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA p450 PF00067.22 KZN89770.1 - 1.1e-56 192.5 0.0 1.6e-56 192.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2 PF00096.26 KZN89771.1 - 2.7e-06 27.5 14.6 0.00022 21.5 1.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KZN89771.1 - 2e-05 24.8 17.5 0.003 17.9 4.9 3.9 4 0 0 4 4 4 2 Zinc-finger double domain Fungal_trans PF04082.18 KZN89771.1 - 4.7e-05 22.6 1.2 7.7e-05 21.8 1.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.6 KZN89771.1 - 0.0002 21.9 12.4 0.0058 17.4 0.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KZN89771.1 - 0.1 13.3 0.9 0.4 11.3 0.4 2.1 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf_C2H2_ZHX PF18387.1 KZN89771.1 - 0.28 10.9 3.2 2.9 7.6 2.0 2.5 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-LYAR PF08790.11 KZN89771.1 - 0.54 10.2 2.9 0.53 10.2 1.3 1.8 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 KZN89771.1 - 0.9 9.6 5.1 17 5.6 0.8 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger COesterase PF00135.28 KZN89773.1 - 1.8e-54 185.5 0.0 2.8e-52 178.2 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KZN89773.1 - 0.00039 20.3 0.0 0.00086 19.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold HgmA PF04209.13 KZN89774.1 - 5e-165 549.3 0.1 5.8e-165 549.1 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Zn_clus PF00172.18 KZN89775.1 - 7.8e-06 25.9 8.6 7.8e-06 25.9 8.6 2.4 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KZN89775.1 - 5.2e-05 23.5 13.4 0.0021 18.4 8.0 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KZN89775.1 - 0.0023 18.3 10.0 0.2 12.2 3.6 3.1 2 0 0 2 2 2 2 Zinc-finger double domain Fungal_trans PF04082.18 KZN89775.1 - 0.0055 15.8 0.4 0.0088 15.1 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.6 KZN89775.1 - 0.026 15.3 17.4 0.25 12.3 6.6 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-MYST PF17772.1 KZN89775.1 - 0.28 10.8 1.8 0.51 10.0 0.9 1.9 1 1 0 1 1 1 0 MYST family zinc finger domain AMP-binding PF00501.28 KZN89776.1 - 3.2e-67 227.0 0.0 4.5e-67 226.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KZN89776.1 - 2.5e-08 34.1 0.1 5.6e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KZN89776.1 - 0.058 14.4 1.1 0.26 12.3 0.2 2.4 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain ATPgrasp_N PF18130.1 KZN89777.1 - 2.2e-14 53.8 0.0 4.2e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 KZN89777.1 - 0.00024 20.8 0.0 0.0025 17.4 0.0 2.4 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KZN89777.1 - 0.0025 17.4 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus DNA_pol3_beta_2 PF02767.16 KZN89777.1 - 0.076 13.2 0.0 0.32 11.2 0.0 1.9 2 0 0 2 2 2 0 DNA polymerase III beta subunit, central domain HTH_19 PF12844.7 KZN89777.1 - 0.11 12.5 0.0 0.44 10.6 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain ATP-grasp PF02222.22 KZN89777.1 - 0.18 11.3 0.0 0.55 9.8 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain Porphobil_deam PF01379.20 KZN89778.1 - 4e-42 144.1 0.0 6.1e-39 133.7 0.0 2.1 1 1 1 2 2 2 2 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KZN89778.1 - 1e-14 54.6 0.0 3.3e-14 53.0 0.1 1.9 2 0 0 2 2 2 1 Porphobilinogen deaminase, C-terminal domain p450 PF00067.22 KZN89779.1 - 6.2e-37 127.4 0.0 8.6e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 KZN89779.1 - 2.7e-06 27.4 4.6 6.7e-06 26.1 4.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mur_ligase_C PF02875.21 KZN89780.1 - 0.029 14.6 0.0 0.046 14.0 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.12 KZN89781.1 - 0.082 12.9 0.0 0.082 12.9 0.0 1.1 1 0 0 1 1 1 0 Mur ligase middle domain NB-ARC PF00931.22 KZN89782.1 - 8e-10 38.3 0.0 1.4e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain DUF676 PF05057.14 KZN89782.1 - 8.9e-08 31.9 0.0 2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KZN89782.1 - 1.4e-05 24.9 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 KZN89782.1 - 0.014 15.2 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 KZN89782.1 - 0.015 15.9 0.0 0.029 14.9 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KZN89782.1 - 0.022 14.1 0.0 0.054 12.7 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Cutinase PF01083.22 KZN89782.1 - 0.051 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Cutinase Ser_hydrolase PF06821.13 KZN89782.1 - 0.082 12.8 0.0 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase DUF3089 PF11288.8 KZN89782.1 - 0.094 12.2 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) RicinB_lectin_2 PF14200.6 KZN89783.1 - 0.011 16.4 0.1 0.33 11.7 0.1 2.2 1 1 2 3 3 3 0 Ricin-type beta-trefoil lectin domain-like Glyco_transf_90 PF05686.12 KZN89784.1 - 3.6e-19 69.0 0.4 1.7e-14 53.5 0.0 3.2 3 0 0 3 3 3 3 Glycosyl transferase family 90 Taeniidae_ag PF05596.11 KZN89784.1 - 0.011 15.7 0.0 0.029 14.4 0.0 1.7 1 0 0 1 1 1 0 Taeniidae antigen NAD_binding_4 PF07993.12 KZN89785.1 - 2.1e-34 118.9 0.0 3.2e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KZN89785.1 - 6.9e-28 97.4 0.0 1.2e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KZN89785.1 - 3.3e-10 39.8 0.0 7.2e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AAA_33 PF13671.6 KZN89785.1 - 1e-08 35.4 0.0 2.5e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain PP-binding PF00550.25 KZN89785.1 - 9e-07 29.2 0.1 3.8e-06 27.1 0.0 2.2 2 0 0 2 2 1 1 Phosphopantetheine attachment site AAA_18 PF13238.6 KZN89785.1 - 9.5e-05 23.0 0.0 0.0018 18.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain APS_kinase PF01583.20 KZN89785.1 - 0.00017 21.5 0.0 0.00042 20.2 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase SKI PF01202.22 KZN89785.1 - 0.00021 21.5 0.0 0.00044 20.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase Rad17 PF03215.15 KZN89785.1 - 0.00047 20.1 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 KZN89785.1 - 0.0024 18.3 0.0 0.006 17.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 KZN89785.1 - 0.0028 17.4 0.0 0.0066 16.2 0.0 1.5 1 0 0 1 1 1 1 Cytidylate kinase AAA_17 PF13207.6 KZN89785.1 - 0.0059 17.0 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KZN89785.1 - 0.0088 16.3 0.0 0.07 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain KR PF08659.10 KZN89785.1 - 0.01 15.8 0.0 0.032 14.2 0.0 1.8 1 0 0 1 1 1 0 KR domain AAA_5 PF07728.14 KZN89785.1 - 0.013 15.5 0.0 0.05 13.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KZN89785.1 - 0.014 15.6 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain CoaE PF01121.20 KZN89785.1 - 0.04 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Dephospho-CoA kinase ABC_tran PF00005.27 KZN89785.1 - 0.046 14.2 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_PrkA PF08298.11 KZN89785.1 - 0.064 12.2 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain dNK PF01712.19 KZN89785.1 - 0.1 12.5 0.0 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 Deoxynucleoside kinase TPP_enzyme_M PF00205.22 KZN89785.1 - 0.1 12.4 0.0 2.4 7.9 0.0 2.6 3 0 0 3 3 2 0 Thiamine pyrophosphate enzyme, central domain GDP_Man_Dehyd PF16363.5 KZN89785.1 - 0.13 11.7 0.0 8.1 5.7 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase EccE PF11203.8 KZN89785.1 - 0.15 12.4 2.2 15 6.0 0.2 3.9 4 0 0 4 4 4 0 Putative type VII ESX secretion system translocon, EccE RNA_helicase PF00910.22 KZN89785.1 - 0.15 12.5 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Aldo_ket_red PF00248.21 KZN89786.1 - 3.2e-44 151.3 0.0 2.5e-43 148.4 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.18 KZN89787.1 - 1.8e-26 92.8 0.0 3e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN89787.1 - 1.8e-05 24.7 8.1 1.8e-05 24.7 8.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KZN89788.1 - 7.6e-41 140.2 27.1 1.8e-40 139.0 26.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Fe-S_assembly PF04384.13 KZN89788.1 - 0.071 13.7 0.1 0.14 12.8 0.1 1.4 1 0 0 1 1 1 0 Iron-sulphur cluster assembly Aa_trans PF01490.18 KZN89789.1 - 3.8e-35 121.4 28.9 4.5e-35 121.2 28.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KZN89789.1 - 0.00022 20.4 13.2 0.00022 20.4 13.2 1.9 2 1 1 3 3 3 1 Tryptophan/tyrosine permease family MYO10_CC PF16735.5 KZN89790.1 - 0.2 11.8 0.4 0.2 11.8 0.4 2.2 3 0 0 3 3 3 0 Unconventional myosin-X coiled coil domain Glyco_hydro_31 PF01055.26 KZN89791.1 - 9.2e-87 292.0 0.3 1.9e-86 291.0 0.5 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KZN89791.1 - 7.3e-13 48.6 0.0 2.3e-12 47.0 0.0 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 KZN89791.1 - 0.0036 17.5 0.0 0.01 16.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) MFS_1 PF07690.16 KZN89792.1 - 5.2e-32 111.1 24.1 4.6e-31 108.0 23.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PalH PF08733.10 KZN89794.1 - 0.0059 15.7 8.5 0.01 14.9 8.5 1.4 1 0 0 1 1 1 1 PalH/RIM21 DUF2721 PF11026.8 KZN89794.1 - 0.4 10.6 15.5 0.1 12.5 0.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) AA_permease_2 PF13520.6 KZN89795.1 - 4.5e-55 187.2 42.1 8.2e-55 186.3 42.1 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN89795.1 - 1.1e-22 80.4 40.6 2.4e-22 79.2 40.6 1.5 1 1 0 1 1 1 1 Amino acid permease p450 PF00067.22 KZN89796.1 - 6.7e-41 140.5 0.0 1.7e-40 139.2 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 KZN89797.1 - 6.3e-10 39.0 12.7 1.3e-09 38.0 12.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.22 KZN89798.1 - 7.7e-184 611.5 0.7 8.7e-184 611.3 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ADH_N PF08240.12 KZN89799.1 - 4.9e-29 100.4 0.6 9.2e-29 99.5 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN89799.1 - 7.2e-22 77.8 0.1 1.2e-21 77.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KZN89799.1 - 0.0008 20.5 0.0 0.0012 19.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KZN89799.1 - 0.0035 16.7 0.1 0.0063 15.9 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KZN89799.1 - 0.02 14.2 0.4 0.033 13.5 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 KZN89799.1 - 0.05 13.1 0.3 0.082 12.3 0.3 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Gpr1_Fun34_YaaH PF01184.19 KZN89801.1 - 3e-29 102.1 22.8 3.6e-29 101.9 22.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family FixS PF03597.15 KZN89801.1 - 0.056 13.2 1.5 0.056 13.2 1.5 3.4 4 0 0 4 4 4 0 Cytochrome oxidase maturation protein cbb3-type TraG_N PF07916.11 KZN89802.1 - 5.6 5.7 6.4 6.5 5.5 6.4 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region TFIIA PF03153.13 KZN89802.1 - 8.2 6.3 25.9 11 5.9 25.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ank_2 PF12796.7 KZN89803.1 - 1e-11 45.2 0.8 0.0014 19.2 0.1 4.7 3 1 2 5 5 5 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN89803.1 - 4.2e-09 36.7 7.3 0.55 10.9 0.1 5.6 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN89803.1 - 2.1e-07 30.7 2.4 0.25 12.0 0.0 6.4 6 1 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 KZN89803.1 - 9.8e-06 25.8 5.8 0.25 11.7 0.1 5.2 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Orthopox_F14 PF06076.12 KZN89803.1 - 0.0048 17.1 0.6 0.1 12.9 0.8 2.9 3 0 0 3 3 3 1 Orthopoxvirus F14 protein Helo_like_N PF17111.5 KZN89803.1 - 0.044 13.1 0.0 0.13 11.6 0.0 1.8 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins GST_N_2 PF13409.6 KZN89804.1 - 1.7e-10 41.0 0.0 2.8e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KZN89804.1 - 2.3e-10 40.7 0.0 4.7e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KZN89804.1 - 3.2e-05 23.9 0.0 0.00021 21.2 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KZN89804.1 - 0.00039 20.6 0.0 0.00092 19.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KZN89804.1 - 0.0029 17.7 0.0 0.0064 16.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Abhydrolase_2 PF02230.16 KZN89805.1 - 2.1e-23 83.3 0.0 8.6e-15 55.1 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KZN89805.1 - 0.0049 16.4 0.0 0.0099 15.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family AF-4 PF05110.13 KZN89805.1 - 4.9 5.1 7.5 6.5 4.7 7.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein APH PF01636.23 KZN89806.1 - 7.4e-12 45.7 0.0 3e-11 43.7 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 KZN89806.1 - 0.14 11.4 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Fructosamine kinase Choline_kinase PF01633.20 KZN89806.1 - 0.14 11.7 0.0 0.37 10.3 0.0 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF2002 PF09400.10 KZN89807.1 - 0.02 14.9 0.1 0.041 13.9 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2002) APH PF01636.23 KZN89809.1 - 2e-09 37.7 0.0 3.8e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ribosomal_S25 PF03297.15 KZN89810.1 - 4.9e-38 129.4 3.1 5.3e-38 129.3 3.1 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_DeoR PF08220.12 KZN89810.1 - 0.033 13.9 0.1 0.044 13.5 0.1 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain MarR_2 PF12802.7 KZN89810.1 - 0.039 13.9 0.1 0.048 13.5 0.1 1.2 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.20 KZN89810.1 - 0.075 13.4 0.1 0.11 12.9 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator HTH_24 PF13412.6 KZN89810.1 - 0.091 12.3 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Cyt-b5 PF00173.28 KZN89811.1 - 1.7e-11 44.1 0.0 2.2e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3989 PF13150.6 KZN89811.1 - 0.07 12.9 0.3 0.15 11.8 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) NQR2_RnfD_RnfE PF03116.15 KZN89811.1 - 0.077 12.4 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 NQR2, RnfD, RnfE family Gtr1_RagA PF04670.12 KZN89812.1 - 1.1e-55 188.5 0.2 2.2e-55 187.5 0.1 1.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 KZN89812.1 - 0.051 13.4 0.1 0.086 12.6 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein cobW PF02492.19 KZN89813.1 - 1.1e-48 165.2 4.8 5.6e-37 127.0 0.7 2.3 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KZN89813.1 - 5.1e-21 74.4 0.0 2.5e-16 59.4 0.0 2.8 3 0 0 3 3 3 2 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.14 KZN89813.1 - 0.0045 16.9 0.0 0.0085 16.0 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.6 KZN89813.1 - 0.01 16.2 0.2 0.03 14.7 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 KZN89813.1 - 0.013 15.5 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 KZN89813.1 - 0.04 13.7 0.1 0.085 12.6 0.1 1.5 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 KZN89813.1 - 0.058 12.5 0.4 0.14 11.2 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_33 PF13671.6 KZN89813.1 - 0.061 13.5 0.0 0.2 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KZN89813.1 - 0.091 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 KZN89813.1 - 0.096 13.0 0.1 0.32 11.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KZN89813.1 - 0.12 12.2 0.1 0.34 10.7 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SelP_N PF04592.14 KZN89813.1 - 0.95 8.8 9.1 12 5.2 6.7 2.4 2 0 0 2 2 2 0 Selenoprotein P, N terminal region adh_short PF00106.25 KZN89814.1 - 1.4e-28 99.7 0.1 4.1e-28 98.2 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN89814.1 - 5.9e-14 52.2 0.0 7.3e-13 48.6 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN89814.1 - 2.9e-05 24.1 0.1 0.00011 22.2 0.1 1.8 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KZN89814.1 - 0.077 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) His_Phos_2 PF00328.22 KZN89815.1 - 2.7e-08 33.6 0.0 8.6e-07 28.6 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Lactamase_B_4 PF13691.6 KZN89816.1 - 4.1e-25 87.2 0.1 9e-25 86.1 0.1 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 KZN89816.1 - 1.9e-13 50.4 0.1 5.2e-11 42.4 0.1 2.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain ACOX PF01756.19 KZN89816.1 - 3.3 7.3 5.0 4.6 6.8 3.4 2.0 2 0 0 2 2 2 0 Acyl-CoA oxidase G0-G1_switch_2 PF15103.6 KZN89816.1 - 5.7 7.4 5.9 8.5 6.9 0.1 2.8 2 0 0 2 2 2 0 G0/G1 switch protein 2 DUF2052 PF09747.9 KZN89816.1 - 9.5 6.3 9.6 14 5.7 4.2 2.6 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) bZIP_1 PF00170.21 KZN89817.1 - 1.1e-06 28.6 11.3 2.6e-06 27.4 11.3 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KZN89817.1 - 0.017 15.2 10.7 0.017 15.2 10.7 2.4 3 1 0 3 3 3 0 Basic region leucine zipper ABC_tran PF00005.27 KZN89818.1 - 5.3e-44 150.1 8.0 4.6e-23 82.2 0.2 3.8 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 KZN89818.1 - 2.5e-16 60.4 7.9 0.00075 19.4 0.5 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KZN89818.1 - 2e-09 37.2 5.4 0.022 14.2 0.0 4.4 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 KZN89818.1 - 1.7e-08 34.4 4.2 1.7e-08 34.4 4.2 2.7 3 0 0 3 3 2 1 ABC transporter MMR_HSR1 PF01926.23 KZN89818.1 - 8.1e-07 29.1 0.3 0.098 12.7 0.2 3.4 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KZN89818.1 - 1.8e-06 27.6 1.6 0.0061 16.3 0.0 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_13 PF13166.6 KZN89818.1 - 1.5e-05 23.9 1.4 0.071 11.7 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 KZN89818.1 - 0.00016 22.0 4.8 0.0056 16.9 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 KZN89818.1 - 0.00018 21.3 7.4 0.031 14.0 0.1 4.0 3 2 0 3 3 3 2 AAA domain AAA_18 PF13238.6 KZN89818.1 - 0.00043 20.8 0.2 2.1 8.9 0.1 2.9 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KZN89818.1 - 0.00045 20.2 0.3 1.7 8.6 0.0 2.9 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.6 KZN89818.1 - 0.00049 20.3 2.0 0.44 10.7 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 KZN89818.1 - 0.00053 20.4 0.9 0.76 10.2 0.0 3.8 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KZN89818.1 - 0.00063 20.0 3.6 0.42 10.9 0.0 3.9 3 2 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KZN89818.1 - 0.0021 18.5 6.3 0.54 10.6 0.2 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.6 KZN89818.1 - 0.0099 15.9 0.3 5.8 7.0 0.0 3.6 4 0 0 4 4 3 0 AAA domain MobB PF03205.14 KZN89818.1 - 0.011 15.7 1.4 0.69 9.8 0.2 3.0 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B MeaB PF03308.16 KZN89818.1 - 0.013 14.5 0.6 4.4 6.2 0.1 2.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 KZN89818.1 - 0.017 15.1 0.5 0.62 10.1 0.0 3.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 KZN89818.1 - 0.018 15.0 5.7 0.87 9.5 0.1 3.2 4 0 0 4 4 2 0 RsgA GTPase AAA_27 PF13514.6 KZN89818.1 - 0.02 14.5 4.0 0.058 13.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KZN89818.1 - 0.02 15.3 0.8 1.5 9.3 0.0 3.0 3 0 0 3 3 2 0 RNA helicase AAA_15 PF13175.6 KZN89818.1 - 0.022 14.5 3.7 0.71 9.5 0.0 3.0 3 1 0 3 3 2 0 AAA ATPase domain AAA_25 PF13481.6 KZN89818.1 - 0.04 13.5 0.2 7 6.2 0.1 3.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KZN89818.1 - 0.044 13.5 0.7 5.7 6.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 KZN89818.1 - 0.075 13.1 8.9 2 8.5 0.2 3.5 4 0 0 4 4 3 0 Helicase HerA, central domain Roc PF08477.13 KZN89818.1 - 0.086 13.1 0.1 15 5.9 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 KZN89818.1 - 0.093 12.2 0.1 3.3 7.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 KZN89818.1 - 0.098 12.6 1.8 16 5.4 0.0 3.8 4 0 0 4 4 3 0 NTPase FtsK_SpoIIIE PF01580.18 KZN89818.1 - 0.099 12.0 2.6 6.1 6.1 0.1 3.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family TsaE PF02367.17 KZN89818.1 - 0.099 12.6 0.1 8.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 KZN89818.1 - 0.11 13.0 0.0 0.11 13.0 0.0 4.4 3 1 0 3 3 3 0 AAA domain TbpB_B_D PF01298.18 KZN89818.1 - 0.12 12.8 0.1 0.26 11.7 0.1 1.5 1 0 0 1 1 1 0 C-lobe and N-lobe beta barrels of Tf-binding protein B TORC_M PF12885.7 KZN89818.1 - 0.13 12.2 0.2 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 Transducer of regulated CREB activity middle domain PduV-EutP PF10662.9 KZN89818.1 - 0.17 11.6 0.4 20 4.9 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.6 KZN89818.1 - 0.39 11.1 4.8 12 6.4 0.0 3.8 4 0 0 4 4 2 0 AAA domain cobW PF02492.19 KZN89818.1 - 0.56 9.8 5.8 2.7 7.5 0.7 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain MoaC PF01967.21 KZN89819.1 - 4.3e-48 162.9 0.6 6.6e-48 162.3 0.6 1.3 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 KZN89819.1 - 5.7e-37 126.5 0.0 2.9e-36 124.2 0.0 2.1 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KZN89819.1 - 8.2e-27 94.6 0.0 1.6e-26 93.6 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KZN89819.1 - 6.1e-05 23.3 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain TrkH PF02386.16 KZN89820.1 - 9.2e-88 294.9 4.8 3e-83 280.0 0.3 2.0 2 0 0 2 2 2 2 Cation transport protein Noc2 PF03715.13 KZN89821.1 - 4.4e-127 423.4 0.1 4.4e-127 423.4 0.1 2.0 3 0 0 3 3 3 1 Noc2p family Nop14 PF04147.12 KZN89821.1 - 0.0021 16.4 0.0 0.0021 16.4 0.0 3.2 3 0 0 3 3 3 1 Nop14-like family BUD22 PF09073.10 KZN89821.1 - 1.2 8.4 54.0 1.3 8.3 33.9 2.1 2 0 0 2 2 2 0 BUD22 VPS28 PF03997.12 KZN89822.1 - 8.5e-73 244.1 0.0 9.9e-73 243.8 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein Methyltransf_16 PF10294.9 KZN89823.1 - 2.5e-20 72.9 0.0 5.8e-20 71.7 0.0 1.6 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KZN89823.1 - 0.0019 18.0 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN89823.1 - 0.0055 17.4 0.0 0.012 16.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN89823.1 - 0.085 12.6 0.0 0.25 11.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Dyp_perox PF04261.12 KZN89824.1 - 0.0011 18.0 0.0 0.032 13.2 0.0 3.0 2 1 0 2 2 2 1 Dyp-type peroxidase family DUF1929 PF09118.11 KZN89826.1 - 4.8e-21 74.9 0.0 1.2e-20 73.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) F5_F8_type_C PF00754.25 KZN89826.1 - 1.5e-11 44.5 0.0 4e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 F5/8 type C domain Kelch_4 PF13418.6 KZN89826.1 - 2.9e-09 36.8 8.3 0.00023 21.1 0.0 4.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 KZN89826.1 - 5.6e-07 29.3 4.9 0.0072 16.3 0.2 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 KZN89826.1 - 1.4e-06 28.3 6.2 0.0074 16.6 0.2 4.6 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.25 KZN89826.1 - 9.5e-06 25.1 7.6 2.9e-05 23.6 0.2 3.6 4 0 0 4 4 4 1 Kelch motif Glyoxal_oxid_N PF07250.11 KZN89826.1 - 1.6e-05 24.3 0.1 0.034 13.4 0.1 2.7 3 0 0 3 3 3 2 Glyoxal oxidase N-terminus Kelch_5 PF13854.6 KZN89826.1 - 0.01 15.8 1.7 2.3 8.3 0.0 3.7 3 0 0 3 3 3 0 Kelch motif CAP_N PF01213.19 KZN89827.1 - 0.027 14.0 1.0 0.04 13.4 1.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DEAD PF00270.29 KZN89828.1 - 2.5e-27 95.7 0.0 9.5e-27 93.9 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KZN89828.1 - 3.9e-23 81.9 0.0 1.2e-22 80.3 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KZN89828.1 - 0.00011 22.2 0.2 0.00036 20.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.14 KZN89828.1 - 0.024 13.5 0.0 0.055 12.3 0.0 1.5 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Pannexin_like PF12534.8 KZN89828.1 - 9.9 5.1 5.5 18 4.3 5.5 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 ATP-synt_G PF04718.15 KZN89829.1 - 2.6e-33 114.8 0.0 4.8e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit ADH_N PF08240.12 KZN89830.1 - 1.2e-26 92.7 2.8 1.2e-26 92.7 2.8 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN89830.1 - 3.7e-13 49.6 0.0 6.1e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KZN89830.1 - 7.1e-05 22.4 0.2 0.37 10.2 0.1 3.2 3 0 0 3 3 3 2 Glucose dehydrogenase C-terminus S1-like PF14444.6 KZN89830.1 - 0.18 11.7 0.2 3.2 7.8 0.0 2.4 2 0 0 2 2 2 0 S1-like Glyco_hydro_31 PF01055.26 KZN89831.1 - 2.7e-162 540.9 1.0 3.4e-162 540.6 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KZN89831.1 - 4.2e-33 114.0 0.0 7.7e-33 113.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KZN89831.1 - 4.4e-16 59.0 0.7 3.1e-15 56.2 0.5 2.6 3 0 0 3 3 3 1 Galactose mutarotase-like Glyco_hydro_16 PF00722.21 KZN89832.1 - 1.6e-43 148.2 2.7 1.6e-43 148.2 2.7 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 CIA30 PF08547.12 KZN89832.1 - 0.01 15.9 0.3 0.018 15.1 0.3 1.4 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) YjcZ PF13990.6 KZN89833.1 - 0.0015 18.0 0.0 0.0028 17.1 0.0 1.5 1 1 0 1 1 1 1 YjcZ-like protein DUF885 PF05960.11 KZN89833.1 - 0.0017 18.1 0.3 0.0033 17.1 0.3 1.4 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Med3 PF11593.8 KZN89833.1 - 0.011 14.9 0.0 0.011 14.9 0.0 2.0 2 1 0 2 2 2 0 Mediator complex subunit 3 fungal DUF4407 PF14362.6 KZN89833.1 - 0.029 13.7 0.4 0.06 12.7 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 KZN89833.1 - 0.052 13.6 1.0 6.6 6.8 0.2 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.8 KZN89833.1 - 0.054 11.0 0.1 3 5.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) tRNA-synt_2b PF00587.25 KZN89834.1 - 3.9e-33 114.9 0.0 6.2e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KZN89834.1 - 3.2e-07 30.4 0.0 8.1e-07 29.1 0.0 1.7 1 1 0 1 1 1 1 Anticodon binding domain HMGL-like PF00682.19 KZN89835.1 - 2.1e-80 270.1 0.0 3e-80 269.6 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KZN89835.1 - 5.5e-23 81.3 0.0 1.2e-22 80.3 0.0 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain DUF3900 PF13039.6 KZN89835.1 - 0.11 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3900) Sulfatase PF00884.23 KZN89836.1 - 2.6e-64 217.6 0.9 3.5e-64 217.1 0.9 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KZN89836.1 - 0.11 12.1 2.6 0.25 10.9 2.6 1.6 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase AMP-binding PF00501.28 KZN89837.1 - 1.5e-67 228.1 0.7 6.5e-37 127.1 0.0 4.5 2 2 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.11 KZN89837.1 - 1.8e-09 38.4 0.0 5.2e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.12 KZN89837.1 - 0.02 14.9 0.3 0.044 13.8 0.3 1.5 1 0 0 1 1 1 0 Gas vesicle protein G Ribosomal_S7 PF00177.21 KZN89838.1 - 2.5e-36 124.6 1.1 3.2e-36 124.2 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SDA1 PF05285.12 KZN89839.1 - 7.1e-91 305.2 53.1 2.8e-89 300.0 44.8 3.1 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 KZN89839.1 - 1.4e-21 76.6 0.6 3.8e-21 75.2 0.3 2.0 2 0 0 2 2 2 1 NUC130/3NT domain RNR_inhib PF08591.10 KZN89840.1 - 4.2e-19 69.8 0.1 8.7e-19 68.8 0.1 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor Neogenin_C PF06583.12 KZN89840.1 - 0.0056 16.6 2.8 0.0072 16.2 2.8 1.1 1 0 0 1 1 1 1 Neogenin C-terminus PARM PF17061.5 KZN89843.1 - 0.0092 16.2 8.0 0.012 15.8 8.0 1.2 1 0 0 1 1 1 1 PARM HicB PF05534.12 KZN89843.1 - 0.063 13.1 0.9 0.12 12.2 0.9 1.4 1 0 0 1 1 1 0 HicB family REV PF00424.18 KZN89843.1 - 0.27 11.3 2.5 0.45 10.6 2.5 1.4 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Gly_transf_sug PF04488.15 KZN89844.1 - 7.5e-12 45.7 0.4 2.1e-11 44.3 0.4 1.8 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KZN89844.1 - 0.17 11.2 0.2 0.33 10.2 0.0 1.5 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain DUF2293 PF10056.9 KZN89846.1 - 3.1e-29 101.0 0.1 2.3e-28 98.2 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) RE_BstXI PF09552.10 KZN89846.1 - 0.0077 15.5 0.1 2.9 7.0 0.0 2.1 2 0 0 2 2 2 2 BstXI restriction endonuclease PHD PF00628.29 KZN89847.1 - 6.1e-08 32.4 6.8 9.7e-08 31.8 6.8 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KZN89847.1 - 0.47 10.0 5.4 0.78 9.4 5.4 1.3 1 0 0 1 1 1 0 PHD-finger PHD_3 PF13922.6 KZN89847.1 - 0.73 10.3 3.5 2.3 8.7 3.5 1.9 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Mtc PF03820.17 KZN89848.1 - 1.2e-119 399.0 0.3 1.4e-119 398.8 0.3 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Amidase PF01425.21 KZN89849.1 - 1.3e-83 281.5 0.6 2.8e-83 280.4 0.6 1.5 1 1 0 1 1 1 1 Amidase Syntaxin-6_N PF09177.11 KZN89849.1 - 0.024 15.2 0.1 0.055 14.0 0.1 1.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Pkinase PF00069.25 KZN89850.1 - 4.6e-49 167.2 0.0 1.2e-48 165.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN89850.1 - 7.9e-18 64.7 0.0 2.2e-17 63.2 0.0 1.7 2 1 0 2 2 2 1 Protein tyrosine kinase Viral_NABP PF05515.11 KZN89850.1 - 0.047 13.5 0.3 0.21 11.4 0.2 2.0 2 0 0 2 2 2 0 Viral nucleic acid binding TAF4 PF05236.14 KZN89851.1 - 2.9e-30 106.0 1.5 5.8e-23 82.0 2.6 2.2 2 0 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.8 KZN89852.1 - 2.6e-83 278.9 0.1 3.7e-83 278.4 0.1 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KZN89852.1 - 1.2e-28 99.6 0.0 2.9e-28 98.3 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 KZN89852.1 - 1.3e-18 67.7 0.1 2.5e-18 66.8 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 KZN89852.1 - 5.1e-16 58.7 0.0 8.2e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 KZN89852.1 - 1.5e-11 44.1 0.0 3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KZN89852.1 - 0.0018 17.8 0.1 0.004 16.7 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KZN89852.1 - 0.008 16.1 0.0 0.019 14.9 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Aminotran_3 PF00202.21 KZN89853.1 - 1.7e-92 310.2 0.0 2.2e-92 309.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III EGF_alliinase PF04863.13 KZN89853.1 - 0.05 14.0 0.0 0.16 12.4 0.0 1.9 1 0 0 1 1 1 0 Alliinase EGF-like domain SRP19 PF01922.17 KZN89854.1 - 1.7e-35 121.8 0.0 2.7e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein FA_hydroxylase PF04116.13 KZN89858.1 - 1.1e-23 84.0 13.3 1.1e-23 84.0 13.3 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF3606 PF12244.8 KZN89858.1 - 0.012 15.5 0.1 0.027 14.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) TCTP PF00838.17 KZN89859.1 - 8.1e-50 169.4 0.2 9.1e-50 169.2 0.2 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Frigida PF07899.11 KZN89859.1 - 0.072 12.3 0.1 0.11 11.8 0.1 1.1 1 0 0 1 1 1 0 Frigida-like protein Ribosomal_S20p PF01649.18 KZN89859.1 - 0.086 13.5 1.0 0.16 12.6 1.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S20 Fungal_trans PF04082.18 KZN89860.1 - 8.8e-14 51.2 0.1 1.6e-13 50.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN89860.1 - 3.6e-11 43.0 11.4 6.2e-11 42.2 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.7 KZN89861.1 - 1.2e-52 176.4 3.5 4e-14 53.0 0.1 6.0 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN89861.1 - 9.3e-41 137.7 11.1 4.5e-08 33.5 0.0 8.3 2 1 7 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 KZN89861.1 - 5.3e-36 121.5 6.5 9.8e-05 22.6 0.0 10.4 11 0 0 11 11 10 8 Ankyrin repeat Ank_3 PF13606.6 KZN89861.1 - 3.8e-33 109.8 0.4 0.00063 20.0 0.0 10.4 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 KZN89861.1 - 1.2e-27 95.6 8.9 1.5e-05 25.2 0.1 8.7 1 1 8 9 9 9 9 Ankyrin repeats (many copies) NACHT PF05729.12 KZN89861.1 - 3.4e-06 27.1 0.0 8.4e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 NACHT domain TBCC_N PF16752.5 KZN89861.1 - 0.0017 18.8 4.8 0.28 11.6 0.3 3.4 3 0 0 3 3 3 2 Tubulin-specific chaperone C N-terminal domain AAA_22 PF13401.6 KZN89861.1 - 0.0072 16.6 0.0 0.022 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain CHAD PF05235.14 KZN89861.1 - 0.028 14.4 0.8 0.31 11.0 0.8 2.6 1 1 0 1 1 1 0 CHAD domain SesA PF17107.5 KZN89861.1 - 0.054 13.7 0.1 2 8.6 0.0 3.3 2 1 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases GAT PF03127.14 KZN89861.1 - 2.5 8.5 5.3 42 4.5 1.3 3.4 3 0 0 3 3 3 0 GAT domain Methyltransf_23 PF13489.6 KZN89862.1 - 1.3e-12 47.8 0.0 2.3e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN89862.1 - 3.3e-09 37.3 0.0 1.1e-08 35.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN89862.1 - 5.5e-05 23.8 0.0 0.00088 20.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN89862.1 - 0.0007 20.2 0.0 0.002 18.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN89862.1 - 0.0011 18.7 0.0 0.0061 16.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KZN89862.1 - 0.0016 18.0 0.0 0.004 16.6 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 KZN89862.1 - 0.056 12.7 0.0 0.3 10.3 0.0 2.0 1 1 0 1 1 1 0 O-methyltransferase domain MTS PF05175.14 KZN89862.1 - 0.076 12.6 0.0 0.21 11.2 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Ubie_methyltran PF01209.18 KZN89862.1 - 0.2 10.9 0.0 3.9 6.7 0.0 2.4 2 1 1 3 3 3 0 ubiE/COQ5 methyltransferase family Glyco_hydro_3_C PF01915.22 KZN89863.1 - 9.1e-47 159.7 0.0 1.5e-46 158.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KZN89863.1 - 5.1e-34 118.1 0.0 1.4e-33 116.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KZN89863.1 - 2.6e-09 37.0 0.0 9.4e-09 35.3 0.0 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain DDR PF08841.10 KZN89863.1 - 0.15 11.0 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DEAD PF00270.29 KZN89864.1 - 2.5e-34 118.5 0.0 8.5e-16 58.2 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KZN89864.1 - 6.7e-20 71.5 0.1 1.6e-19 70.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KZN89864.1 - 3.1e-07 30.5 0.0 1.4e-06 28.5 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PIGA PF08288.12 KZN89865.1 - 5.7e-46 155.0 2.2 1.3e-45 153.9 1.0 2.1 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 KZN89865.1 - 2.1e-28 99.5 0.2 3.2e-28 98.8 0.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KZN89865.1 - 6.1e-27 94.2 0.0 9.5e-27 93.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KZN89865.1 - 4.3e-24 85.5 0.0 8.8e-24 84.5 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KZN89865.1 - 1.4e-12 48.3 0.0 2.5e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 KZN89865.1 - 0.00015 21.8 0.1 0.00033 20.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 KZN89865.1 - 0.00091 19.6 0.0 0.024 15.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KZN89865.1 - 0.046 13.4 0.0 0.089 12.5 0.0 1.6 1 1 0 1 1 1 0 Starch synthase catalytic domain Arf PF00025.21 KZN89866.1 - 1.3e-39 135.4 0.0 4.6e-26 91.3 0.0 2.3 2 1 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 KZN89866.1 - 2.3e-14 53.3 0.0 6e-08 32.2 0.0 2.1 2 0 0 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KZN89866.1 - 3.6e-10 40.1 0.0 1.3e-09 38.4 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KZN89866.1 - 2e-06 27.9 0.0 5e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KZN89866.1 - 2.2e-06 27.2 0.0 3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 KZN89866.1 - 4.3e-06 26.4 0.0 0.0027 17.3 0.0 2.7 2 1 0 2 2 2 2 Ras family SRPRB PF09439.10 KZN89866.1 - 1.4e-05 24.6 0.0 0.00012 21.6 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KZN89866.1 - 0.0004 20.0 0.0 0.015 14.9 0.0 2.4 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KZN89866.1 - 0.092 12.3 0.0 0.18 11.3 0.0 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.27 KZN89866.1 - 0.15 12.6 0.0 0.26 11.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter HD PF01966.22 KZN89868.1 - 3.1e-06 27.4 0.0 4.9e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 HD domain Prp18 PF02840.15 KZN89869.1 - 7e-55 185.0 0.1 7e-55 185.0 0.1 2.0 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 KZN89869.1 - 7.9e-09 34.9 0.8 7.9e-09 34.9 0.8 2.9 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like V_ATPase_I PF01496.19 KZN89869.1 - 0.62 7.9 3.9 1 7.2 3.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TFIIA PF03153.13 KZN89869.1 - 0.88 9.5 9.0 1.5 8.7 9.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SAP18 PF06487.12 KZN89870.1 - 1.9e-46 157.7 0.0 2.3e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) GST_N PF02798.20 KZN89871.1 - 1.1e-12 48.1 0.1 3.2e-12 46.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KZN89871.1 - 1.7e-09 37.8 0.0 4.1e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KZN89871.1 - 3.3e-09 37.0 0.1 9.4e-09 35.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KZN89871.1 - 9.5e-07 28.8 0.0 3.1e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KZN89871.1 - 5.8e-06 26.4 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KZN89871.1 - 0.00022 21.4 0.0 0.0004 20.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KZN89871.1 - 0.01 16.4 0.0 0.025 15.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain 2-Hacid_dh_C PF02826.19 KZN89872.1 - 4.5e-52 176.0 0.0 6.4e-52 175.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KZN89872.1 - 1.8e-29 102.1 0.0 2e-29 101.9 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.21 KZN89872.1 - 0.004 16.5 0.1 0.22 10.8 0.1 2.2 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 KZN89872.1 - 0.076 13.2 0.0 0.18 12.0 0.0 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ferrochelatase PF00762.19 KZN89872.1 - 0.08 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Ferrochelatase FYVE PF01363.21 KZN89873.1 - 5.5e-15 55.3 7.6 8.8e-15 54.6 7.6 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 KZN89873.1 - 0.022 14.9 9.9 0.043 14.0 9.9 1.4 1 0 0 1 1 1 0 AN1-like Zinc finger Acetyltransf_1 PF00583.25 KZN89874.1 - 7.4e-08 32.6 0.0 1.3e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.6 KZN89874.1 - 3.5e-06 27.7 0.0 6.9e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KZN89874.1 - 2.4e-05 24.3 0.0 0.1 12.5 0.0 2.6 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KZN89874.1 - 7e-05 23.2 0.0 0.00016 22.0 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KZN89874.1 - 0.00088 19.4 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KZN89874.1 - 0.16 11.9 0.0 0.56 10.2 0.0 1.9 2 0 0 2 2 2 0 FR47-like protein Methyltr_RsmB-F PF01189.17 KZN89875.1 - 6e-16 58.7 0.0 5.7e-10 39.2 0.0 2.6 3 0 0 3 3 3 2 16S rRNA methyltransferase RsmB/F Ribosomal_60s PF00428.19 KZN89875.1 - 0.017 15.7 3.4 0.017 15.7 3.4 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein CENP-B_dimeris PF09026.10 KZN89875.1 - 6.3 7.2 9.5 15 6.0 9.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BTB_2 PF02214.22 KZN89876.1 - 5.5e-08 33.0 1.1 0.0018 18.6 0.2 2.3 2 0 0 2 2 2 2 BTB/POZ domain GMC_oxred_N PF00732.19 KZN89877.1 - 3.4e-48 164.5 0.8 4.7e-48 164.1 0.8 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KZN89877.1 - 1.1e-31 110.3 0.3 1.5e-30 106.7 0.0 2.4 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KZN89877.1 - 5e-06 25.8 0.3 9.4e-06 25.0 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 KZN89877.1 - 1.8e-05 24.2 0.0 3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KZN89877.1 - 2e-05 24.7 0.1 0.0002 21.5 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KZN89877.1 - 2e-05 24.0 0.2 4.7e-05 22.8 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KZN89877.1 - 8.7e-05 22.3 0.2 0.0027 17.4 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KZN89877.1 - 0.00013 21.3 0.0 0.002 17.4 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 KZN89877.1 - 0.0086 15.5 0.4 0.014 14.8 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KZN89877.1 - 0.015 14.0 0.0 0.03 13.0 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 KZN89877.1 - 0.048 12.7 0.1 0.38 9.8 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 KZN89877.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase ThiF PF00899.21 KZN89877.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 ThiF family GST_N PF02798.20 KZN89878.1 - 1.6e-14 54.0 0.0 2.6e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KZN89878.1 - 9.2e-12 45.0 0.0 1.5e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KZN89878.1 - 8.6e-10 38.9 0.0 1.5e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KZN89878.1 - 5.6e-09 35.9 0.0 1.1e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KZN89878.1 - 6.7e-08 32.6 0.0 1.5e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KZN89878.1 - 1e-05 25.8 0.0 1.6e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KZN89878.1 - 0.031 15.0 0.0 0.055 14.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 KZN89878.1 - 0.091 13.1 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Pyr_redox_2 PF07992.14 KZN89879.1 - 2.6e-27 95.8 0.0 7.8e-27 94.3 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KZN89879.1 - 3.9e-16 59.4 0.1 2.6e-13 50.3 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KZN89879.1 - 5.7e-05 22.4 0.3 0.00014 21.1 0.0 1.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KZN89879.1 - 0.0021 17.7 1.5 0.39 10.2 0.2 3.2 4 0 0 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KZN89879.1 - 0.017 14.4 0.0 0.28 10.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KZN89879.1 - 0.099 11.7 0.2 0.22 10.5 0.2 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein NaeI PF09126.10 KZN89879.1 - 0.16 11.2 0.1 0.22 10.7 0.1 1.2 1 0 0 1 1 1 0 Restriction endonuclease NaeI AMP-binding PF00501.28 KZN89880.1 - 4.2e-106 355.1 0.0 5.4e-106 354.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KZN89880.1 - 5.9e-12 46.4 0.0 1.3e-11 45.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain OPT PF03169.15 KZN89881.1 - 9.8e-156 519.9 43.9 1.1e-155 519.8 43.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CcmD PF04995.14 KZN89881.1 - 0.013 15.6 0.3 0.013 15.6 0.3 3.2 4 0 0 4 4 4 0 Heme exporter protein D (CcmD) Ppx-GppA PF02541.16 KZN89882.1 - 2.8e-42 145.1 0.0 8e-42 143.6 0.0 1.6 1 1 0 1 1 1 1 Ppx/GppA phosphatase family DUF3578 PF12102.8 KZN89882.1 - 0.066 12.8 0.0 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3578) Ferrochelatase PF00762.19 KZN89882.1 - 0.16 11.0 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Ferrochelatase Ferric_reduct PF01794.19 KZN89883.1 - 2.4e-24 85.8 15.7 4.6e-24 84.9 15.7 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KZN89883.1 - 1.4e-11 44.5 0.0 0.00025 21.1 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.12 KZN89883.1 - 9.7e-11 42.0 0.0 2.7e-05 24.3 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KZN89883.1 - 0.023 15.3 0.0 0.07 13.8 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Hydrophobin PF01185.18 KZN89884.1 - 3.6e-08 33.9 11.1 4.6e-08 33.6 11.1 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Fungal_trans PF04082.18 KZN89885.1 - 1.7e-24 86.3 0.1 2.3e-24 85.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN89886.1 - 7.3e-10 38.8 6.9 1.4e-09 37.9 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN89886.1 - 1.3e-06 27.7 0.2 2.6e-06 26.7 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KZN89888.1 - 7.8e-16 57.9 14.7 7.8e-16 57.9 14.7 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF4131 PF13567.6 KZN89888.1 - 0.75 9.4 15.7 0.57 9.8 1.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) CRAL_TRIO PF00650.20 KZN89890.1 - 2.3e-44 150.9 0.0 3.9e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KZN89890.1 - 4e-11 42.9 0.0 1.2e-10 41.4 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KZN89890.1 - 1.9e-05 24.8 0.0 3.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF5371 PF17341.2 KZN89890.1 - 0.2 11.9 1.6 0.27 11.5 0.3 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5371) ADP_ribosyl_GH PF03747.14 KZN89891.1 - 6.6e-59 200.0 1.4 7.7e-59 199.8 1.4 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Acetyltransf_1 PF00583.25 KZN89892.1 - 2.8e-13 50.1 0.0 3.7e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KZN89892.1 - 6.7e-10 39.0 0.0 9.3e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KZN89892.1 - 2.4e-08 34.3 0.0 3.7e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KZN89892.1 - 5.6e-05 23.3 0.0 7.6e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KZN89892.1 - 0.00013 21.9 0.0 0.00028 20.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KZN89892.1 - 0.0031 17.6 0.0 0.0054 16.8 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Arginase PF00491.21 KZN89893.1 - 3.8e-58 197.2 0.0 6.2e-58 196.5 0.0 1.3 1 1 0 1 1 1 1 Arginase family MFS_1 PF07690.16 KZN89894.1 - 7.8e-36 123.7 24.8 1.1e-35 123.2 24.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN89894.1 - 1.3e-07 30.9 19.1 3.4e-07 29.5 17.8 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 KZN89894.1 - 4.6e-05 22.9 5.1 4.6e-05 22.9 5.1 1.7 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Peptidase_M24 PF00557.24 KZN89896.1 - 1.3e-40 139.4 0.0 1.8e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Fungal_trans PF04082.18 KZN89897.1 - 4.4e-20 71.8 0.6 7.5e-20 71.1 0.3 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain TauD PF02668.16 KZN89898.1 - 9.2e-29 101.1 0.0 1.6e-28 100.3 0.0 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-Fe_Oxy_2 PF10014.9 KZN89898.1 - 0.073 12.9 0.1 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 2OG-Fe dioxygenase LssY_C PF14067.6 KZN89898.1 - 0.16 11.5 0.0 11 5.6 0.0 2.3 2 0 0 2 2 2 0 LssY C-terminus Form_Nir_trans PF01226.17 KZN89899.1 - 2.3e-69 233.4 20.6 2.6e-69 233.2 20.6 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter DUF2107 PF09880.9 KZN89899.1 - 0.00073 19.6 0.7 0.3 11.2 0.0 2.4 2 0 0 2 2 2 2 Predicted membrane protein (DUF2107) MFS_1 PF07690.16 KZN89900.1 - 3.7e-34 118.2 29.4 4.3e-34 118.0 27.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN89900.1 - 0.00052 19.0 19.3 0.0039 16.1 19.4 2.3 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 KZN89900.1 - 0.00058 19.3 1.2 0.00058 19.3 1.2 2.6 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB ketoacyl-synt PF00109.26 KZN89901.1 - 3.7e-75 252.8 0.0 8.4e-75 251.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 KZN89901.1 - 3.7e-74 249.8 0.1 6.6e-74 249.0 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KZN89901.1 - 2.8e-61 207.6 0.0 4.2e-61 207.0 0.0 1.2 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.6 KZN89901.1 - 9.5e-54 182.6 0.0 1.8e-53 181.7 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KZN89901.1 - 4.7e-53 179.8 0.1 1.5e-51 174.9 0.0 2.6 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 KZN89901.1 - 1.7e-43 149.4 0.1 3.4e-43 148.4 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 KZN89901.1 - 2.5e-33 115.3 0.0 1e-32 113.4 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.22 KZN89901.1 - 3.5e-30 104.4 0.0 7.2e-30 103.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KZN89901.1 - 3e-17 62.7 0.6 4.7e-09 36.5 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Epimerase PF01370.21 KZN89901.1 - 5.3e-15 55.5 0.0 1.2e-13 51.1 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KZN89901.1 - 7.3e-14 51.7 0.1 1.5e-12 47.4 0.0 2.8 3 0 0 3 3 3 1 short chain dehydrogenase Methyltransf_12 PF08242.12 KZN89901.1 - 3.3e-13 50.2 0.0 8.1e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN89901.1 - 9.5e-13 48.2 0.0 2.3e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KZN89901.1 - 3.9e-12 46.6 0.0 1.2e-11 45.1 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KZN89901.1 - 5.5e-12 46.2 0.0 2.1e-11 44.4 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN89901.1 - 5.8e-10 39.7 0.0 1.7e-09 38.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN89901.1 - 1.3e-09 38.2 0.0 2.9e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.19 KZN89901.1 - 2.6e-07 30.0 0.0 8.7e-07 28.2 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.23 KZN89901.1 - 1.7e-05 24.4 0.0 3.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain GDP_Man_Dehyd PF16363.5 KZN89901.1 - 0.00032 20.2 0.0 0.0089 15.5 0.0 2.3 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NodS PF05401.11 KZN89901.1 - 0.00033 20.3 0.0 0.00064 19.4 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) NAD_binding_10 PF13460.6 KZN89901.1 - 0.00037 20.4 0.0 0.001 19.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)H-binding AMP-binding_C PF13193.6 KZN89901.1 - 0.00053 20.9 0.0 0.0013 19.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ubie_methyltran PF01209.18 KZN89901.1 - 0.0013 18.1 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KZN89901.1 - 0.0073 16.1 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Semialdhyde_dh PF01118.24 KZN89901.1 - 0.081 13.4 0.0 0.23 11.9 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GCD14 PF08704.10 KZN89901.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit ADH_zinc_N PF00107.26 KZN89902.1 - 1.9e-08 34.3 0.0 3.3e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KZN89902.1 - 0.00031 21.8 0.0 0.0014 19.6 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Zn_clus PF00172.18 KZN89904.1 - 0.0001 22.4 7.7 0.0002 21.4 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KZN89905.1 - 8.9e-56 189.5 0.1 1.2e-55 189.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1910 PF08928.10 KZN89905.1 - 0.033 14.2 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) Acyl-CoA_dh_1 PF00441.24 KZN89906.1 - 5.8e-34 117.5 1.5 9.2e-34 116.8 1.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KZN89906.1 - 8.9e-19 67.5 0.1 1.5e-18 66.8 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KZN89906.1 - 7.2e-13 49.0 0.2 1.3e-12 48.2 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KZN89906.1 - 0.00065 19.5 0.0 0.00098 18.9 0.0 1.3 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_dh_N PF02771.16 KZN89906.1 - 0.028 15.1 0.0 0.075 13.7 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain PH_BEACH PF14844.6 KZN89906.1 - 0.046 13.8 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH AA_permease PF00324.21 KZN89907.1 - 1.6e-128 429.3 48.6 2e-128 429.0 48.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KZN89907.1 - 6.3e-30 104.4 52.9 7.8e-30 104.0 52.9 1.0 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 KZN89908.1 - 2.3e-22 79.4 71.7 3.7e-18 65.6 45.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Phosphoesterase PF04185.14 KZN89909.1 - 7.2e-79 265.6 1.1 8.8e-79 265.3 1.1 1.1 1 0 0 1 1 1 1 Phosphoesterase family Sulfatase PF00884.23 KZN89909.1 - 0.001 18.6 0.2 3.1 7.1 0.0 3.1 3 0 0 3 3 3 3 Sulfatase Transketolase_N PF00456.21 KZN89910.1 - 4.3e-128 427.0 0.0 5.9e-128 426.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KZN89910.1 - 7.6e-42 143.0 0.0 1.3e-41 142.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KZN89910.1 - 1.2e-06 28.4 0.0 2.8e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KZN89910.1 - 5.7e-06 25.7 0.0 2.1e-05 23.9 0.0 1.8 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 KZN89910.1 - 1.2e-05 24.4 0.0 3.5e-05 22.9 0.1 1.7 2 0 0 2 2 2 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KZN89910.1 - 2.7e-05 24.0 0.4 0.0003 20.6 0.7 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain ADH_N PF08240.12 KZN89911.1 - 4e-30 103.9 0.9 8.3e-30 102.9 0.9 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN89911.1 - 1.4e-14 54.2 0.0 2.1e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KZN89911.1 - 2.4e-05 23.9 0.7 0.00047 19.7 0.7 2.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KZN89911.1 - 0.011 15.1 0.8 0.052 12.8 0.1 2.2 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KZN89911.1 - 0.031 13.5 0.7 0.67 9.1 0.3 2.3 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans_2 PF11951.8 KZN89913.1 - 4.6e-15 55.3 3.9 1.5e-14 53.6 3.9 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KZN89913.1 - 0.012 14.6 0.6 0.017 14.2 0.1 1.4 2 0 0 2 2 2 0 Fungal specific transcription factor domain MIT PF04212.18 KZN89913.1 - 0.6 10.2 0.0 0.6 10.2 0.0 2.7 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain Zn_clus PF00172.18 KZN89914.1 - 1.2e-08 34.9 9.1 2.2e-08 34.1 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMO-like PF00743.19 KZN89915.1 - 5.7e-06 25.0 0.0 0.0062 15.0 0.0 2.9 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KZN89915.1 - 6.7e-05 22.2 0.2 0.0054 15.9 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KZN89915.1 - 0.00051 19.4 0.2 0.057 12.6 0.1 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KZN89915.1 - 0.0008 18.7 0.0 0.017 14.4 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KZN89915.1 - 0.0028 17.6 0.3 0.53 10.3 0.0 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KZN89915.1 - 0.0094 16.2 0.2 3.6 7.9 0.4 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KZN89915.1 - 0.12 11.1 0.0 1.6 7.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyridoxal_deC PF00282.19 KZN89916.1 - 9e-99 330.7 0.0 1.2e-98 330.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Epimerase PF01370.21 KZN89916.1 - 2.9e-15 56.4 0.0 5.5e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KZN89916.1 - 1.3e-12 47.3 0.0 7.5e-12 44.8 0.0 2.1 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KZN89916.1 - 7.8e-10 38.9 0.1 2.5e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KZN89916.1 - 1e-09 38.0 0.0 3.4e-08 33.0 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KZN89916.1 - 3.5e-07 29.9 0.0 6.9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KZN89916.1 - 1.2e-05 25.0 0.0 3e-05 23.7 0.1 1.6 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 KZN89916.1 - 0.00095 18.7 0.0 0.0019 17.7 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KZN89916.1 - 0.0011 18.2 0.1 0.003 16.8 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Beta_elim_lyase PF01212.21 KZN89916.1 - 0.004 16.5 0.0 0.0063 15.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase KR PF08659.10 KZN89916.1 - 0.037 13.9 0.5 0.25 11.2 0.5 2.0 1 1 0 1 1 1 0 KR domain Cupin_2 PF07883.11 KZN89917.1 - 3.8e-08 32.9 0.0 6.3e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KZN89917.1 - 0.052 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) SIR2 PF02146.17 KZN89918.1 - 3.3e-50 170.5 0.0 5.3e-50 169.8 0.0 1.3 1 0 0 1 1 1 1 Sir2 family Zn_clus PF00172.18 KZN89919.1 - 4e-08 33.2 10.0 7.4e-08 32.4 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KZN89920.1 - 1.9e-29 102.7 48.7 6e-24 84.6 27.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BRI3BP PF14965.6 KZN89920.1 - 0.14 11.6 2.2 0.4 10.2 2.2 1.8 1 0 0 1 1 1 0 Negative regulator of p53/TP53 Glyco_hydro_32C PF08244.12 KZN89922.1 - 4.3e-22 78.8 0.7 7.1e-22 78.1 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.20 KZN89922.1 - 2.1e-14 53.8 0.0 4.3e-14 52.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain YL1_C PF08265.11 KZN89922.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain p450 PF00067.22 KZN89924.1 - 3e-61 207.6 0.0 4.2e-61 207.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S28 PF05577.12 KZN89925.1 - 6.6e-59 199.8 2.0 1.9e-58 198.3 0.9 2.0 2 0 0 2 2 2 1 Serine carboxypeptidase S28 adh_short_C2 PF13561.6 KZN89926.1 - 2.4e-54 184.4 0.6 4.7e-43 147.4 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN89926.1 - 1.3e-48 165.0 0.7 4.3e-48 163.4 0.7 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN89926.1 - 3.8e-05 23.7 0.5 0.0028 17.6 0.4 2.2 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 KZN89926.1 - 0.035 13.4 0.1 0.082 12.2 0.1 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Peptidase_S10 PF00450.22 KZN89927.1 - 5.4e-90 302.8 0.0 6.8e-90 302.5 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase NAD_binding_10 PF13460.6 KZN89928.1 - 5.7e-07 29.6 0.0 7.5e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KZN89928.1 - 0.0017 17.6 0.0 0.0027 16.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 KZN89928.1 - 0.0064 16.8 0.0 0.0097 16.2 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KZN89928.1 - 0.013 16.0 0.0 0.026 15.0 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KZN89928.1 - 0.032 13.7 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.10 KZN89928.1 - 0.052 13.5 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 KZN89928.1 - 0.23 10.5 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RhgB_N PF09284.10 KZN89929.1 - 5e-109 363.7 4.6 5e-109 363.7 4.6 1.6 2 0 0 2 2 2 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 KZN89929.1 - 6.1e-44 149.8 0.0 2e-43 148.1 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KZN89929.1 - 1.7e-23 82.1 6.8 1.7e-23 82.1 6.8 2.6 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KZN89929.1 - 0.00026 21.2 0.8 0.00026 21.2 0.8 4.6 7 0 0 7 7 7 1 Carboxypeptidase regulatory-like domain Amidohydro_1 PF01979.20 KZN89930.1 - 1.6e-59 201.9 0.0 2.7e-59 201.2 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KZN89930.1 - 5e-06 26.3 0.3 0.00097 18.7 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 KZN89930.1 - 0.15 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Adenosine/AMP deaminase GDC-P PF02347.16 KZN89931.1 - 3.2e-172 573.2 0.0 1.6e-161 538.0 0.0 2.3 2 1 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 KZN89931.1 - 0.00024 20.5 0.2 0.00048 19.5 0.2 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KZN89931.1 - 0.082 12.2 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family MFS_1 PF07690.16 KZN89932.1 - 1.2e-35 123.1 30.6 1.2e-35 123.1 30.6 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF962 PF06127.11 KZN89932.1 - 0.47 10.6 3.4 2.5 8.2 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF962) MFS_1 PF07690.16 KZN89933.1 - 6e-16 58.3 14.2 8.7e-16 57.8 13.2 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN89933.1 - 8.3e-10 38.1 0.4 8.3e-10 38.1 0.4 2.5 1 1 1 2 2 2 2 Sugar (and other) transporter TMEM208_SND2 PF05620.11 KZN89933.1 - 0.37 10.5 4.0 0.38 10.5 0.0 3.0 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 MFS_1 PF07690.16 KZN89934.1 - 1.4e-40 139.3 53.0 1.4e-40 139.3 53.0 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN89934.1 - 1.1e-09 37.7 11.8 1.1e-09 37.7 11.8 3.4 2 1 1 3 3 3 2 Sugar (and other) transporter SnoaL_2 PF12680.7 KZN89935.1 - 0.0029 18.2 0.0 0.016 15.8 0.0 2.1 2 0 0 2 2 2 1 SnoaL-like domain DLH PF01738.18 KZN89935.1 - 0.016 14.8 0.0 0.043 13.4 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family SnoaL PF07366.12 KZN89935.1 - 0.04 13.7 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase RIO1 PF01163.22 KZN89936.1 - 0.00076 19.1 0.0 0.0018 17.9 0.0 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KZN89936.1 - 0.0016 18.4 0.1 0.0016 18.4 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family HSDR_N_2 PF13588.6 KZN89936.1 - 0.041 13.9 0.0 0.16 12.0 0.0 2.0 1 1 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Casc1_N PF15927.5 KZN89936.1 - 0.5 10.0 14.8 1.4 8.6 14.8 1.7 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Hydrolase_6 PF13344.6 KZN89937.1 - 1.8e-20 72.9 0.0 3e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KZN89937.1 - 2.7e-13 49.7 0.0 1.2e-12 47.7 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KZN89937.1 - 0.16 12.3 0.0 13 6.0 0.0 2.9 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Sugar_tr PF00083.24 KZN89939.1 - 2.3e-94 316.8 21.6 2.9e-94 316.5 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN89939.1 - 1.3e-27 96.7 30.1 9.1e-26 90.6 15.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Hydantoinase_B PF02538.14 KZN89940.1 - 5.5e-126 421.0 0.0 7.9e-126 420.5 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KZN89940.1 - 8.1e-92 307.6 3.9 2.2e-91 306.1 1.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KZN89940.1 - 7.5e-49 165.8 0.1 3.7e-46 157.1 0.0 2.7 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 KZN89940.1 - 0.00021 20.1 0.9 0.27 9.8 0.1 2.5 2 0 0 2 2 2 2 MutL protein FtsA PF14450.6 KZN89940.1 - 0.0012 19.2 0.5 2.6 8.5 0.1 2.8 2 0 0 2 2 2 2 Cell division protein FtsA Ppx-GppA PF02541.16 KZN89940.1 - 0.098 12.1 0.1 0.26 10.7 0.0 1.7 2 0 0 2 2 2 0 Ppx/GppA phosphatase family HEPN_Swt1 PF18731.1 KZN89940.1 - 0.17 12.3 0.3 0.41 11.0 0.3 1.6 1 0 0 1 1 1 0 Swt1-like HEPN DDR PF08841.10 KZN89940.1 - 0.25 10.3 1.7 2.8 6.9 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain MFS_1 PF07690.16 KZN89942.1 - 1.3e-27 96.7 34.3 9.6e-15 54.3 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KZN89942.1 - 0.00082 18.3 20.8 0.04 12.8 10.3 2.1 1 1 1 2 2 2 2 MFS_1 like family ATG22 PF11700.8 KZN89942.1 - 0.0075 15.0 0.6 0.0075 15.0 0.6 3.1 3 1 1 4 4 4 1 Vacuole effluxer Atg22 like p450 PF00067.22 KZN89943.1 - 9.2e-75 252.1 0.0 1.1e-74 251.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_1 PF00175.21 KZN89944.1 - 3.4e-34 117.8 0.0 6.6e-34 116.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KZN89944.1 - 3.3e-28 98.0 0.0 1.2e-27 96.2 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 KZN89944.1 - 2.7e-21 75.5 0.0 4.6e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KZN89944.1 - 5e-06 26.7 0.0 0.00064 19.9 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain MDMPI_N PF11716.8 KZN89944.1 - 0.0076 16.9 0.1 0.021 15.5 0.1 1.7 1 0 0 1 1 1 1 Mycothiol maleylpyruvate isomerase N-terminal domain FAD_binding_9 PF08021.11 KZN89944.1 - 0.031 14.5 0.0 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain GreA_GreB PF01272.19 KZN89944.1 - 0.085 12.8 0.1 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 Transcription elongation factor, GreA/GreB, C-term Mid2 PF04478.12 KZN89945.1 - 0.005 16.7 0.0 0.0081 16.0 0.0 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DALR_2 PF09190.11 KZN89946.1 - 0.16 12.5 0.0 18 5.9 0.0 2.4 2 0 0 2 2 2 0 DALR domain MFS_1 PF07690.16 KZN89947.1 - 1.3e-32 113.2 26.7 1.3e-32 113.2 26.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KZN89947.1 - 0.00024 20.8 3.2 0.00072 19.3 3.2 1.7 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 GDPD_2 PF13653.6 KZN89948.1 - 0.012 16.1 0.3 0.049 14.1 0.7 2.0 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family GDPD PF03009.17 KZN89948.1 - 0.078 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family CoA_trans PF01144.23 KZN89949.1 - 4.1e-100 333.6 1.3 1.3e-61 207.8 0.1 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KZN89949.1 - 0.0037 17.2 1.2 0.0047 16.9 0.1 1.6 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase C-terminal domain Fungal_trans PF04082.18 KZN89950.1 - 0.0036 16.4 0.1 0.008 15.2 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF2207 PF09972.9 KZN89951.1 - 0.00085 18.2 0.7 0.00085 18.2 0.7 1.8 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) Snf7 PF03357.21 KZN89952.1 - 0.014 15.0 8.4 0.018 14.6 8.4 1.1 1 0 0 1 1 1 0 Snf7 bZIP_2 PF07716.15 KZN89953.1 - 1.6e-11 44.1 15.4 1.6e-11 44.1 15.4 2.4 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 KZN89953.1 - 3.5e-07 30.2 16.5 6.3e-07 29.4 16.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KZN89953.1 - 0.0011 19.4 13.7 0.0011 19.4 13.7 1.8 2 0 0 2 2 2 1 bZIP Maf transcription factor FPP PF05911.11 KZN89953.1 - 0.0019 16.5 5.2 0.0027 16.0 5.2 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil APG6_N PF17675.1 KZN89953.1 - 0.23 12.0 11.8 0.39 11.2 11.8 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region CENP-H PF05837.12 KZN89953.1 - 0.73 10.3 9.6 1.8 9.0 9.6 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Bystin PF05291.11 KZN89954.1 - 6.5e-130 432.7 0.0 8.3e-130 432.3 0.0 1.1 1 0 0 1 1 1 1 Bystin Amidase PF01425.21 KZN89956.1 - 7.4e-120 401.0 0.6 8.9e-120 400.7 0.6 1.0 1 0 0 1 1 1 1 Amidase ADH_zinc_N PF00107.26 KZN89957.1 - 5.6e-14 52.2 0.0 9.5e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF4265 PF14085.6 KZN89957.1 - 0.034 14.1 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) ADH_N PF08240.12 KZN89957.1 - 0.077 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Metallophos PF00149.28 KZN89958.1 - 2.5e-10 41.2 2.7 1.2e-09 39.0 1.2 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 KZN89958.1 - 0.094 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain Transket_pyr PF02779.24 KZN89959.1 - 1.2e-46 158.6 0.0 1.9e-46 158.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KZN89959.1 - 3.3e-36 123.9 0.2 2.8e-35 120.9 0.1 2.3 2 0 0 2 2 2 1 Transketolase, C-terminal domain zf-C2H2 PF00096.26 KZN89960.1 - 0.0027 18.0 1.2 0.0055 17.1 1.2 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.7 KZN89960.1 - 0.0049 17.2 0.3 0.0082 16.5 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KZN89960.1 - 0.014 15.7 1.9 0.022 15.1 1.9 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KZN89960.1 - 0.062 13.6 0.2 0.093 13.1 0.2 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.11 KZN89960.1 - 0.064 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger zf-C2H2_4 PF13894.6 KZN89960.1 - 0.075 13.9 0.5 0.16 12.9 0.5 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger DUF1691 PF07950.11 KZN89961.1 - 5.5e-42 142.8 6.8 6.2e-34 117.0 3.4 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) TRM PF02005.16 KZN89962.1 - 1.3e-114 383.3 0.0 2e-99 333.3 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 KZN89962.1 - 0.00032 20.5 0.0 0.00052 19.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein DUF2067 PF09840.9 KZN89962.1 - 0.00079 19.0 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2067) Methyltransf_25 PF13649.6 KZN89962.1 - 0.011 16.4 0.0 0.027 15.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Trypan_PARP PF05887.11 KZN89962.1 - 0.018 15.0 13.6 0.036 14.1 6.7 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Methyltransf_31 PF13847.6 KZN89962.1 - 0.091 12.6 1.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.13 KZN89962.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KZN89962.1 - 0.16 11.5 0.0 0.4 10.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain DUF4091 PF13320.6 KZN89962.1 - 0.17 12.0 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4091) CCDC53 PF10152.9 KZN89962.1 - 7.2 7.0 8.9 2.5 8.5 2.9 2.6 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex DUF1729 PF08354.10 KZN89963.1 - 3.7e-161 535.9 0.0 6e-161 535.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 KZN89963.1 - 4.8e-91 305.6 0.0 2.2e-89 300.1 0.0 3.2 4 0 0 4 4 4 1 Acyl transferase domain FAS_meander PF17951.1 KZN89963.1 - 1.6e-51 174.0 0.0 6.5e-51 172.0 0.0 2.1 2 0 0 2 2 2 1 Fatty acid synthase meander beta sheet domain FAS_N PF17828.1 KZN89963.1 - 7.2e-43 145.7 0.0 1.9e-42 144.3 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydratas PF01575.19 KZN89963.1 - 1.5e-38 131.1 0.0 3.6e-38 129.9 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain SAT PF16073.5 KZN89963.1 - 4.2e-38 131.4 0.1 1.4e-37 129.7 0.0 2.0 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydrat_N PF13452.6 KZN89963.1 - 1.9e-21 76.6 0.0 7.1e-21 74.7 0.0 2.0 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.15 KZN89963.1 - 0.11 11.9 0.4 0.77 9.1 0.4 2.2 1 1 0 1 1 1 0 Nitronate monooxygenase FAS_I_H PF18314.1 KZN89964.1 - 1.4e-78 263.2 0.0 1.4e-78 263.2 0.0 2.0 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 KZN89964.1 - 1.2e-76 256.6 0.0 2.5e-76 255.5 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 KZN89964.1 - 7.5e-22 78.1 0.0 1.8e-21 76.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 KZN89964.1 - 4.3e-17 62.3 0.0 1e-16 61.1 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 KZN89964.1 - 5.6e-12 45.7 0.6 1.9e-11 44.0 0.0 2.2 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 KZN89964.1 - 0.0014 18.6 0.0 0.0058 16.6 0.0 2.0 1 0 0 1 1 1 1 KR domain TFIIF_alpha PF05793.12 KZN89965.1 - 8.4e-08 31.2 56.0 2.3e-07 29.8 6.1 3.1 1 1 1 3 3 3 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) OPT PF03169.15 KZN89966.1 - 1.3e-199 664.9 37.5 1.5e-199 664.7 37.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF383 PF04063.14 KZN89967.1 - 2.4e-70 236.1 0.3 1e-69 234.1 0.1 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 KZN89967.1 - 3.7e-23 81.1 4.1 7.7e-23 80.1 0.8 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF384) MlaA PF04333.13 KZN89967.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 MlaA lipoprotein Inositol_P PF00459.25 KZN89968.1 - 1.9e-65 221.1 0.0 2.3e-65 220.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF676 PF05057.14 KZN89969.1 - 9.1e-42 143.0 0.1 2.1e-27 96.1 0.0 3.2 3 0 0 3 3 3 3 Putative serine esterase (DUF676) Lipase_3 PF01764.25 KZN89969.1 - 0.0037 17.1 0.0 0.0095 15.8 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) DUF915 PF06028.11 KZN89969.1 - 0.036 13.4 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DAGK_cat PF00781.24 KZN89970.1 - 8.8e-14 51.2 0.0 1.3e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain His_Phos_2 PF00328.22 KZN89971.1 - 2e-110 369.8 0.0 2.7e-110 369.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KZN89971.1 - 3.2e-37 126.6 0.0 6.6e-37 125.6 0.0 1.6 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KZN89971.1 - 5.6e-05 22.8 0.0 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.12 KZN89972.1 - 2e-80 269.6 0.0 3.1e-80 269.0 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 KZN89972.1 - 3.8e-14 52.8 0.0 0.02 15.2 0.0 6.5 2 2 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KZN89972.1 - 1.1e-07 32.4 38.4 5.2e-05 23.9 0.4 9.8 11 1 0 11 11 11 4 WD domain, G-beta repeat Nup160 PF11715.8 KZN89972.1 - 0.0021 16.8 0.0 1.4 7.5 0.0 3.1 3 0 0 3 3 3 2 Nucleoporin Nup120/160 XPG_I_2 PF12813.7 KZN89973.1 - 1.1e-85 287.1 0.0 1.5e-85 286.7 0.0 1.1 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.18 KZN89973.1 - 0.027 14.8 0.1 0.062 13.7 0.1 1.5 1 0 0 1 1 1 0 XPG I-region Fcf1 PF04900.12 KZN89974.1 - 3.4e-36 123.6 0.2 6.1e-36 122.8 0.2 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 KZN89974.1 - 5.8e-11 42.7 0.4 8.4e-11 42.2 0.0 1.5 2 0 0 2 2 2 1 PIN like domain IF-2B PF01008.17 KZN89975.1 - 5.7e-73 245.6 4.1 6.6e-73 245.4 4.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family LSM PF01423.22 KZN89976.1 - 4.9e-20 71.0 0.1 5.4e-20 70.8 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KZN89976.1 - 0.00085 19.4 0.0 0.00095 19.3 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KZN89976.1 - 0.0052 16.9 0.1 0.0056 16.8 0.1 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain Rad60-SLD PF11976.8 KZN89977.1 - 3e-21 75.0 0.1 4.7e-18 64.8 0.2 2.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KZN89977.1 - 0.00016 21.3 0.0 0.0065 16.2 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin family CK1gamma_C PF12605.8 KZN89977.1 - 0.053 14.7 5.9 0.13 13.4 5.9 1.7 1 0 0 1 1 1 0 Casein kinase 1 gamma C terminal Trm112p PF03966.16 KZN89978.1 - 4.2e-15 56.1 0.0 5.1e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein CBX7_C PF17218.3 KZN89978.1 - 0.09 12.5 1.8 0.19 11.5 1.8 1.6 1 0 0 1 1 1 0 CBX family C-terminal motif Zn_ribbon_recom PF13408.6 KZN89978.1 - 0.1 13.1 0.6 0.19 12.3 0.6 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain N-SET PF11764.8 KZN89979.1 - 2.4e-56 190.5 1.2 2.4e-56 190.5 1.2 2.3 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 KZN89979.1 - 2.8e-26 90.9 0.8 8.2e-26 89.4 0.8 1.9 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.28 KZN89979.1 - 1.1e-19 71.5 0.2 1.1e-19 71.5 0.2 3.6 2 1 0 2 2 2 1 SET domain RRM_1 PF00076.22 KZN89979.1 - 0.0004 20.2 0.0 0.00082 19.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.18 KZN89981.1 - 2.4e-10 40.4 10.2 4.3e-10 39.5 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN89981.1 - 1.2e-09 37.6 0.1 2e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AA_permease_2 PF13520.6 KZN89982.1 - 6.4e-42 143.9 47.1 6.4e-42 143.9 47.1 3.1 2 1 1 3 3 3 1 Amino acid permease MFS_1 PF07690.16 KZN89982.1 - 6.8e-30 104.2 48.4 6.8e-30 104.2 48.4 5.5 3 2 1 4 4 4 1 Major Facilitator Superfamily AA_permease PF00324.21 KZN89982.1 - 4.5e-19 68.4 38.6 4.5e-19 68.4 38.6 2.5 2 0 0 2 2 2 1 Amino acid permease Pyr_redox_3 PF13738.6 KZN89982.1 - 1.3e-08 34.5 0.0 2.5e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.24 KZN89982.1 - 1.6e-05 23.9 14.3 1.6e-05 23.9 14.3 4.8 4 2 1 5 5 5 2 Sugar (and other) transporter Pyr_redox_2 PF07992.14 KZN89982.1 - 7.8e-05 22.0 0.0 0.0016 17.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KZN89982.1 - 0.00042 19.6 0.0 0.00088 18.5 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KZN89983.1 - 4.6e-19 69.2 0.0 5.3e-19 69.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF1188 PF06690.11 KZN89983.1 - 0.05 13.1 0.0 0.48 9.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) Cupin_3 PF05899.12 KZN89984.1 - 1.4e-10 40.7 0.4 2.2e-10 40.1 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 KZN89984.1 - 1.2e-05 24.9 0.1 2.3e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 KZN89984.1 - 0.0013 18.5 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Cupin EutQ PF06249.12 KZN89984.1 - 0.0069 16.2 0.1 0.0083 15.9 0.1 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ AraC_binding_2 PF14525.6 KZN89984.1 - 0.014 15.1 0.0 0.02 14.6 0.0 1.1 1 0 0 1 1 1 0 AraC-binding-like domain HutD PF05962.11 KZN89984.1 - 0.021 14.8 0.0 0.026 14.5 0.0 1.1 1 0 0 1 1 1 0 HutD AraC_binding PF02311.19 KZN89984.1 - 0.039 13.9 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Fungal_trans_2 PF11951.8 KZN89985.1 - 3e-20 72.4 12.4 5.5e-20 71.5 12.4 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN89985.1 - 3.2e-08 33.6 7.5 6.1e-08 32.7 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.19 KZN89986.1 - 3.4e-51 174.4 0.0 4.5e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KZN89986.1 - 3.8e-33 115.0 0.0 6.3e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KZN89986.1 - 0.00011 21.4 0.2 0.00018 20.7 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KZN89986.1 - 0.0031 17.2 0.6 0.0085 15.7 0.6 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KZN89986.1 - 0.0069 15.5 0.5 2.3 7.2 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KZN89986.1 - 0.013 14.7 0.2 0.037 13.2 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KZN89986.1 - 0.084 12.1 0.1 0.47 9.7 0.0 2.0 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.6 KZN89986.1 - 0.14 12.5 0.2 0.37 11.0 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Fungal_trans_2 PF11951.8 KZN89987.1 - 2.6e-38 131.9 0.6 3e-38 131.6 0.6 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN89987.1 - 2.4e-08 34.0 10.0 2.4e-08 34.0 10.0 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMO-like PF00743.19 KZN89988.1 - 3.4e-13 48.9 0.0 7.4e-13 47.8 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KZN89988.1 - 1.2e-09 37.8 0.0 7.6e-08 31.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN89988.1 - 2.9e-07 30.6 0.0 7e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KZN89988.1 - 2.6e-06 26.9 0.0 6.5e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KZN89988.1 - 5e-06 26.0 0.0 2.5e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KZN89988.1 - 0.001 18.4 0.6 1.2 8.3 0.0 2.3 1 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 KZN89988.1 - 0.0026 17.4 0.0 2.7 7.5 0.0 3.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KZN89988.1 - 0.0074 15.4 0.1 0.012 14.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Integrin_b_cyt PF08725.11 KZN89988.1 - 0.0076 15.9 0.3 0.018 14.7 0.3 1.6 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain GIDA PF01134.22 KZN89988.1 - 0.0095 15.1 0.9 1.6 7.7 0.1 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KZN89988.1 - 0.015 15.3 0.2 3.1 7.8 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 KZN89988.1 - 0.12 11.7 0.0 0.3 10.4 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 KZN89988.1 - 0.14 11.3 0.1 0.32 10.2 0.1 1.6 1 0 0 1 1 1 0 Thi4 family Cupin_3 PF05899.12 KZN89989.1 - 4.5e-07 29.5 0.3 6.9e-07 28.9 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 KZN89989.1 - 0.00081 19.1 0.1 0.0013 18.4 0.1 1.3 1 0 0 1 1 1 1 Cupin domain p450 PF00067.22 KZN89990.1 - 3.6e-43 148.0 0.0 4.4e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Aldedh PF00171.22 KZN89991.1 - 3.2e-181 602.9 0.3 3.6e-181 602.7 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DAO PF01266.24 KZN89992.1 - 3.2e-44 152.0 0.2 3.7e-44 151.8 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KZN89992.1 - 0.02 14.9 0.1 0.81 9.7 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KZN89992.1 - 0.034 13.4 0.0 0.47 9.7 0.0 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN89992.1 - 0.051 13.8 0.2 0.13 12.5 0.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KZN89992.1 - 0.087 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Aldedh PF00171.22 KZN89993.1 - 2.2e-158 527.6 0.4 2.5e-158 527.4 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NmrA PF05368.13 KZN89994.1 - 4.1e-27 95.3 0.0 5.4e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KZN89994.1 - 2.8e-07 30.6 0.0 4.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KZN89994.1 - 0.00028 21.3 0.0 0.00063 20.2 0.0 1.7 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KZN89994.1 - 0.0004 19.9 0.0 0.00082 18.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KZN89994.1 - 0.0014 18.9 0.1 0.0043 17.3 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KZN89994.1 - 0.015 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 KR domain TrkA_N PF02254.18 KZN89994.1 - 0.016 15.5 0.0 0.069 13.4 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain DapB_N PF01113.20 KZN89994.1 - 0.073 13.2 0.0 0.16 12.1 0.0 1.6 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Aldedh PF00171.22 KZN89995.1 - 6.5e-179 595.3 1.3 7.4e-179 595.1 1.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4717 PF15838.5 KZN89995.1 - 0.021 14.8 0.2 0.051 13.6 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4717) Oxidored_FMN PF00724.20 KZN89996.1 - 4.8e-37 128.0 0.0 8.1e-37 127.3 0.0 1.3 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family SIS PF01380.22 KZN89998.1 - 1.2e-57 193.4 0.0 1.2e-30 106.0 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KZN89998.1 - 1.9e-17 63.7 0.0 3.7e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KZN89998.1 - 5.6e-11 42.4 0.0 1.3e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KZN89998.1 - 6.2e-05 22.0 0.0 0.0001 21.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 KZN89998.1 - 0.13 11.0 0.0 0.46 9.1 0.0 1.7 2 0 0 2 2 2 0 Glutamine amidotransferases class-II DMRL_synthase PF00885.19 KZN89999.1 - 2.2e-57 192.8 0.1 2.8e-57 192.5 0.1 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DUF2108 PF09881.9 KZN89999.1 - 0.09 12.8 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2108) Proteasome PF00227.26 KZN90000.1 - 1e-46 158.9 0.9 1.4e-32 112.8 0.0 2.5 3 0 0 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.9 KZN90000.1 - 5.4e-12 45.2 1.0 6.3e-12 44.9 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5633 PF18656.1 KZN90000.1 - 0.84 9.6 6.7 0.34 10.8 2.3 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5633) Iso_dh PF00180.20 KZN90003.1 - 1.6e-84 284.0 0.0 2e-84 283.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase WBS_methylT PF12589.8 KZN90004.1 - 1.6e-14 54.4 0.6 3e-14 53.5 0.6 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_25 PF13649.6 KZN90004.1 - 2.3e-11 44.2 0.0 6.9e-11 42.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN90004.1 - 4.4e-11 43.3 0.0 8.1e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN90004.1 - 7e-06 26.7 0.0 2.2e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN90004.1 - 3.9e-05 23.5 0.0 5.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KZN90004.1 - 0.00033 20.5 0.0 0.00056 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 KZN90004.1 - 0.0023 17.3 0.0 0.0063 15.9 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KZN90004.1 - 0.012 15.5 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 KZN90004.1 - 0.062 12.6 0.0 0.97 8.7 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_33 PF10017.9 KZN90004.1 - 0.089 11.9 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Erv26 PF04148.13 KZN90005.1 - 4e-93 310.9 0.0 4.5e-93 310.8 0.0 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF1970 PF09301.10 KZN90005.1 - 0.083 13.2 0.0 0.2 11.9 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1970) RhoGAP PF00620.27 KZN90006.1 - 2.2e-41 141.2 0.1 4.5e-41 140.2 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KZN90006.1 - 4.6e-15 56.0 0.0 1e-14 54.9 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KZN90006.1 - 9.8e-06 25.9 0.0 2.6e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KZN90006.1 - 0.0045 17.3 0.0 0.054 13.8 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain MDM31_MDM32 PF08118.11 KZN90007.1 - 1.9e-249 828.7 0.0 4.3e-249 827.6 0.0 1.6 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins KH_8 PF17903.1 KZN90008.1 - 0.00012 22.1 0.0 0.00025 21.0 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KZN90008.1 - 0.023 14.5 1.0 0.048 13.5 1.0 1.5 1 0 0 1 1 1 0 KH domain Proteasome PF00227.26 KZN90009.1 - 8.5e-33 113.4 0.4 3.5e-31 108.2 0.2 2.1 2 0 0 2 2 2 2 Proteasome subunit HCNGP PF07818.13 KZN90010.1 - 2.2e-30 105.1 0.6 3.4e-30 104.6 0.6 1.3 1 0 0 1 1 1 1 HCNGP-like protein Late_protein_L2 PF00513.18 KZN90010.1 - 0.0095 15.0 0.5 0.012 14.7 0.5 1.1 1 0 0 1 1 1 1 Late Protein L2 Proteasome PF00227.26 KZN90012.1 - 1.7e-28 99.4 0.0 2e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit FAA_hydrolase PF01557.18 KZN90013.1 - 1.6e-65 220.9 0.0 1.9e-65 220.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GspH PF12019.8 KZN90013.1 - 0.042 14.3 0.2 0.071 13.5 0.2 1.4 1 0 0 1 1 1 0 Type II transport protein GspH DUF2437 PF10370.9 KZN90013.1 - 0.088 13.7 0.1 0.61 11.0 0.1 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2437) HSP20 PF00011.21 KZN90014.1 - 5.3e-18 65.1 0.1 1.8e-12 47.3 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KZN90014.1 - 0.00049 19.6 0.0 0.0067 16.0 0.0 2.1 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Autophagy_act_C PF03987.15 KZN90016.1 - 7.3e-15 55.3 0.3 1.5e-14 54.3 0.3 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain RRM_1 PF00076.22 KZN90017.1 - 2.5e-08 33.6 0.1 5.1e-08 32.6 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KZN90017.1 - 2.7e-05 23.8 0.0 3.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.12 KZN90017.1 - 0.014 15.2 0.1 0.014 15.2 0.1 1.7 2 1 0 2 2 2 0 Calcipressin Limkain-b1 PF11608.8 KZN90017.1 - 0.099 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 WD40 PF00400.32 KZN90018.1 - 1.2e-17 63.9 11.2 0.00022 21.9 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN90018.1 - 8.9e-07 29.1 0.0 0.024 14.9 0.0 4.6 5 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2388 PF09498.10 KZN90018.1 - 0.21 11.6 1.9 0.39 10.7 0.2 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2388) Lipase_3 PF01764.25 KZN90019.1 - 1.5e-28 99.5 0.0 2.1e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KZN90019.1 - 0.0019 18.9 3.4 0.0029 18.2 3.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KZN90019.1 - 0.0062 15.8 0.0 0.0093 15.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 CYTL1 PF15153.6 KZN90019.1 - 0.011 15.7 0.1 0.018 15.0 0.1 1.3 1 0 0 1 1 1 0 Cytokine-like protein 1 Thioesterase PF00975.20 KZN90019.1 - 0.066 13.3 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 KZN90019.1 - 0.077 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.20 KZN90019.1 - 0.087 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.8 KZN90019.1 - 0.23 11.0 0.0 1.3 8.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) WW PF00397.26 KZN90020.1 - 1.4e-11 44.3 0.4 3.6e-11 42.9 0.4 1.8 1 0 0 1 1 1 1 WW domain PhoD PF09423.10 KZN90020.1 - 0.042 12.9 0.1 0.075 12.0 0.1 1.4 1 0 0 1 1 1 0 PhoD-like phosphatase APH PF01636.23 KZN90021.1 - 6.5e-12 45.9 0.0 2e-11 44.3 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fungal_trans_2 PF11951.8 KZN90022.1 - 2e-16 59.8 5.2 2.8e-16 59.3 5.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ecm29 PF13001.7 KZN90023.1 - 6.5e-162 539.7 0.0 4.5e-160 533.6 0.0 2.7 2 1 0 2 2 2 1 Proteasome stabiliser HEAT_EZ PF13513.6 KZN90023.1 - 7.4e-07 29.5 7.5 0.56 10.8 0.0 8.0 8 1 1 9 9 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KZN90023.1 - 3.7e-05 24.2 0.6 0.049 14.2 0.0 5.1 4 2 2 6 6 6 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KZN90023.1 - 0.002 18.2 7.1 5.7 7.5 0.1 7.1 7 0 0 7 7 7 1 HEAT repeat IFRD PF05004.13 KZN90023.1 - 0.039 13.1 2.0 1.4 7.9 0.1 3.7 4 1 0 4 4 4 0 Interferon-related developmental regulator (IFRD) SNF2_N PF00176.23 KZN90024.1 - 5.6e-56 189.8 0.0 1.2e-55 188.7 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.6 KZN90024.1 - 5.9e-08 32.4 9.4 5.9e-08 32.4 9.4 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KZN90024.1 - 7.1e-08 32.2 8.5 1.9e-07 30.9 8.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KZN90024.1 - 7.2e-08 32.2 8.1 1.7e-07 31.0 8.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KZN90024.1 - 1.5e-06 28.4 10.1 3.6e-06 27.2 10.1 1.7 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KZN90024.1 - 2.7e-06 27.1 7.3 5.9e-06 26.1 7.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KZN90024.1 - 0.00033 20.9 8.1 0.0009 19.5 8.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KZN90024.1 - 0.00075 19.5 6.3 0.0023 17.9 6.3 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Helicase_C PF00271.31 KZN90024.1 - 0.0014 18.9 0.0 0.0033 17.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 KZN90024.1 - 0.002 18.0 8.5 0.002 18.0 8.5 1.8 2 0 0 2 2 1 1 zinc-RING finger domain TPR_2 PF07719.17 KZN90024.1 - 0.025 14.7 0.5 0.091 12.9 0.5 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-C3HC4_4 PF15227.6 KZN90024.1 - 0.054 13.7 8.1 0.12 12.6 8.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 KZN90024.1 - 0.06 13.3 0.3 0.16 11.9 0.3 1.7 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) TPR_12 PF13424.6 KZN90024.1 - 0.072 13.4 0.5 0.25 11.6 0.5 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-RING_4 PF14570.6 KZN90024.1 - 0.33 10.8 6.1 1.4 8.8 5.7 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 KZN90024.1 - 0.79 9.4 8.2 1.8 8.3 8.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-P11 PF03854.14 KZN90024.1 - 3.6 7.3 7.8 7.4 6.3 7.8 1.5 1 0 0 1 1 1 0 P-11 zinc finger PNGaseA PF12222.8 KZN90025.1 - 9.2e-167 555.3 1.7 1.4e-164 548.1 1.7 2.1 1 1 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF1640 PF07798.11 KZN90026.1 - 3.9e-56 189.9 8.1 4.9e-56 189.5 8.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) PMM PF03332.13 KZN90027.1 - 7.4e-101 336.5 0.3 8.5e-101 336.3 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KZN90027.1 - 0.00075 19.3 0.0 0.0021 17.8 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KZN90027.1 - 0.011 15.3 0.0 2.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase DnaJ PF00226.31 KZN90029.1 - 2.3e-09 37.2 0.9 6.8e-09 35.7 0.8 1.9 1 1 0 1 1 1 1 DnaJ domain PRA1 PF03208.19 KZN90030.1 - 1.8e-37 128.2 1.4 2.1e-37 127.9 1.4 1.0 1 0 0 1 1 1 1 PRA1 family protein Frag1 PF10277.9 KZN90032.1 - 9.1e-44 149.6 11.2 1e-43 149.4 11.2 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF973 PF06157.11 KZN90032.1 - 0.013 14.5 3.7 0.017 14.2 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) CPP1-like PF11833.8 KZN90032.1 - 0.11 12.2 0.6 0.26 10.9 0.5 1.7 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Y_phosphatase3 PF13350.6 KZN90033.1 - 1.6e-41 142.8 0.1 5.8e-41 141.0 0.1 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KZN90033.1 - 4.9e-07 29.5 0.0 1.1e-06 28.3 0.0 1.5 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KZN90033.1 - 0.0085 15.7 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KZN90033.1 - 0.073 12.9 0.0 0.24 11.2 0.0 1.8 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.14 KZN90033.1 - 0.17 10.8 0.0 0.34 9.8 0.0 1.4 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Glyco_hydro_35 PF01301.19 KZN90034.1 - 1.7e-80 271.0 4.4 2.4e-80 270.5 4.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KZN90034.1 - 3.3e-60 201.7 0.5 1.8e-32 112.3 0.0 3.0 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KZN90034.1 - 5e-55 186.1 4.1 1.1e-54 184.9 4.1 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KZN90034.1 - 2.1e-22 78.5 0.2 5.8e-22 77.0 0.2 1.8 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 KZN90034.1 - 3.8e-08 33.1 1.9 0.0019 17.7 0.0 3.3 2 1 1 3 3 3 2 Cellulase (glycosyl hydrolase family 5) Ank_4 PF13637.6 KZN90035.1 - 4.2e-39 132.4 4.9 9.3e-08 32.5 0.0 8.5 3 3 6 9 9 9 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 KZN90035.1 - 6e-38 129.3 1.0 8.1e-12 45.6 0.2 4.5 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 KZN90035.1 - 4e-33 112.4 13.6 1.9e-05 24.9 0.2 8.9 9 0 0 9 9 9 6 Ankyrin repeat Ank_3 PF13606.6 KZN90035.1 - 7.9e-30 99.6 5.5 0.00082 19.6 0.0 9.3 9 1 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 KZN90035.1 - 4.7e-28 96.9 7.0 3e-10 40.1 0.7 6.2 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Eisosome1 PF12757.7 KZN90036.1 - 1.4e-35 122.3 12.7 1.4e-35 122.3 12.7 3.1 2 1 0 2 2 2 1 Eisosome protein 1 Glyco_hydro_18 PF00704.28 KZN90037.1 - 2e-72 244.6 4.5 2.9e-72 244.0 4.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KZN90037.1 - 1.5e-13 50.9 45.3 8.5e-13 48.5 18.3 6.9 6 1 1 7 7 7 2 Chitin recognition protein PHC2_SAM_assoc PF16616.5 KZN90037.1 - 5.1 7.9 12.1 31 5.4 11.1 2.3 1 1 1 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 MGC-24 PF05283.11 KZN90038.1 - 0.11 13.0 6.1 0.16 12.4 6.1 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FSA_C PF10479.9 KZN90038.1 - 10 4.1 10.6 13 3.8 10.6 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus LysM PF01476.20 KZN90039.1 - 6.5e-08 32.5 0.0 0.017 15.2 0.0 3.3 3 0 0 3 3 3 3 LysM domain Peptidase_M91 PF14891.6 KZN90040.1 - 0.0044 17.4 0.0 0.008 16.5 0.0 1.5 1 0 0 1 1 1 1 Effector protein DUF4718 PF15842.5 KZN90040.1 - 0.061 13.1 0.1 0.092 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Aspzincin_M35 PF14521.6 KZN90040.1 - 0.081 13.5 2.2 0.25 11.9 0.5 2.7 2 1 0 2 2 2 0 Lysine-specific metallo-endopeptidase Ank_2 PF12796.7 KZN90041.1 - 8.7e-27 93.5 0.6 1.6e-12 47.8 0.1 4.7 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN90041.1 - 3.9e-24 84.7 4.5 3e-09 37.2 0.2 7.7 5 2 3 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN90041.1 - 2.9e-23 79.4 6.3 0.0038 17.6 0.0 9.1 8 1 1 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 KZN90041.1 - 3.2e-16 59.2 2.8 1.2e-08 35.0 0.1 6.3 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 KZN90041.1 - 1e-15 57.3 7.8 0.021 15.2 0.0 7.7 8 0 0 8 8 8 4 Ankyrin repeat F-box PF00646.33 KZN90041.1 - 0.011 15.6 1.0 0.021 14.7 1.0 1.5 1 0 0 1 1 1 0 F-box domain DUF2384 PF09722.10 KZN90041.1 - 0.036 14.1 0.0 0.49 10.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2384) WD40 PF00400.32 KZN90042.1 - 4.7e-16 58.9 1.7 9.8e-09 35.7 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN90042.1 - 0.00051 20.3 0.0 0.34 11.2 0.0 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain NACHT_N PF17100.5 KZN90042.1 - 0.024 14.5 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase MFS_1 PF07690.16 KZN90043.1 - 1.5e-31 109.6 19.5 1.5e-31 109.6 19.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN90043.1 - 4.5e-11 42.3 10.5 4.5e-11 42.3 10.5 2.9 4 0 0 4 4 4 1 Sugar (and other) transporter Gly-zipper_Omp PF13488.6 KZN90043.1 - 0.36 10.8 0.1 0.36 10.8 0.1 2.3 2 1 0 2 2 2 0 Glycine zipper CBFD_NFYB_HMF PF00808.23 KZN90044.1 - 4.9e-29 100.4 0.6 6.6e-29 100.0 0.6 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KZN90044.1 - 4.5e-06 27.0 0.0 6.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 KZN90044.1 - 0.00026 21.0 0.0 0.0004 20.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 KZN90044.1 - 0.00041 20.3 0.1 0.00064 19.7 0.1 1.2 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 KZN90044.1 - 0.0091 16.1 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CFEM PF05730.11 KZN90045.1 - 4.1e-11 42.8 13.0 8.7e-11 41.8 13.0 1.6 1 0 0 1 1 1 1 CFEM domain Mucin PF01456.17 KZN90045.1 - 0.86 9.6 25.0 1.3 9.1 25.0 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein BPS1 PF05633.11 KZN90045.1 - 1.7 7.6 5.0 1.8 7.5 5.0 1.1 1 0 0 1 1 1 0 Protein BYPASS1-related Ilm1 PF10311.9 KZN90046.1 - 1.8e-51 174.1 1.5 2.1e-51 173.8 1.5 1.1 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 SP24 PF16504.5 KZN90046.1 - 0.038 14.0 0.3 0.038 14.0 0.3 1.9 2 0 0 2 2 2 0 Putative virion membrane protein of plant and insect virus ScsC_N PF18312.1 KZN90046.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain Prenyltrans PF00432.21 KZN90047.1 - 4.8e-34 115.8 11.5 4.9e-07 29.4 0.2 6.5 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KZN90047.1 - 0.0096 15.0 0.0 0.086 11.9 0.0 2.3 2 1 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain Pkinase PF00069.25 KZN90048.1 - 1.1e-66 225.0 0.0 1.6e-66 224.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN90048.1 - 1.2e-42 146.0 0.0 1.8e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KZN90048.1 - 9.3e-08 31.7 0.0 3.6e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KZN90048.1 - 2.4e-06 26.8 0.0 2.4e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KZN90048.1 - 0.0048 16.3 0.3 0.022 14.1 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family PRKG1_interact PF15898.5 KZN90048.1 - 0.017 16.0 4.6 0.077 13.9 4.6 2.1 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain APH PF01636.23 KZN90048.1 - 0.12 12.2 4.3 0.96 9.3 0.1 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 KZN90048.1 - 3 7.4 5.1 1.6 8.3 0.0 2.5 3 0 0 3 3 3 0 RIO1 family MFS_1 PF07690.16 KZN90049.1 - 1.5e-14 53.7 41.0 2e-14 53.3 35.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN90049.1 - 4e-06 25.9 1.9 4e-06 25.9 1.9 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter HlyIII PF03006.20 KZN90049.1 - 0.023 14.4 0.2 0.023 14.4 0.2 3.0 2 2 0 2 2 2 0 Haemolysin-III related DUF4293 PF14126.6 KZN90049.1 - 0.051 13.8 0.4 0.051 13.8 0.4 2.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4293) E1-E2_ATPase PF00122.20 KZN90050.1 - 2.5e-50 170.5 6.9 2.9e-50 170.3 0.9 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KZN90050.1 - 2.1e-46 157.9 5.8 2.1e-46 157.9 5.8 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KZN90050.1 - 1.8e-22 80.7 1.2 1.3e-21 77.9 1.2 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KZN90050.1 - 8.9e-19 67.0 0.2 2.7e-18 65.4 0.1 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KZN90050.1 - 6.4e-18 64.6 0.0 1.2e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KZN90050.1 - 2.2e-07 30.9 1.6 1.6e-05 24.8 1.3 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KZN90050.1 - 8.7e-06 26.3 0.0 3.9e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase baeRF_family2 PF18844.1 KZN90050.1 - 0.06 13.4 0.2 15 5.6 0.1 3.3 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 2 eIF3_subunit PF08597.10 KZN90052.1 - 2.7e-71 240.3 28.4 3e-71 240.1 28.4 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Dsh_C PF12316.8 KZN90052.1 - 4.3 7.7 7.7 0.75 10.2 2.2 2.0 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal DUF4746 PF15928.5 KZN90052.1 - 5.1 6.4 20.5 3.2 7.1 16.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Enolase_C PF00113.22 KZN90053.1 - 8.6e-152 504.5 0.0 1.1e-151 504.1 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KZN90053.1 - 1.2e-57 193.7 0.3 2.5e-57 192.7 0.2 1.6 2 0 0 2 2 2 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KZN90053.1 - 3.6e-05 23.4 0.0 6.7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KZN90053.1 - 0.02 14.1 0.3 0.83 8.8 0.1 2.7 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus AAA PF00004.29 KZN90054.1 - 1.3e-42 145.3 0.0 2.2e-42 144.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KZN90054.1 - 1.1e-10 41.1 0.1 2.2e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KZN90054.1 - 1.6e-10 40.7 0.1 1.1e-09 38.1 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 KZN90054.1 - 1.3e-07 32.2 0.0 5.9e-05 23.5 0.1 2.7 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KZN90054.1 - 2.1e-06 27.8 0.0 4.6e-05 23.4 0.0 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KZN90054.1 - 5e-06 26.7 0.1 1.9e-05 24.8 0.0 2.0 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KZN90054.1 - 1.1e-05 25.3 0.0 2.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KZN90054.1 - 0.00032 19.9 0.0 0.00074 18.8 0.0 1.6 2 0 0 2 2 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KZN90054.1 - 0.00056 20.2 0.1 0.019 15.3 0.0 2.4 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 KZN90054.1 - 0.0014 17.9 0.2 0.0051 16.1 0.0 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_18 PF13238.6 KZN90054.1 - 0.0023 18.5 0.0 0.0072 16.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KZN90054.1 - 0.0023 17.4 0.0 0.0048 16.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 KZN90054.1 - 0.006 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KZN90054.1 - 0.006 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 KZN90054.1 - 0.0069 16.1 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 KZN90054.1 - 0.0071 16.1 0.0 0.024 14.4 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain TsaE PF02367.17 KZN90054.1 - 0.0071 16.3 0.0 0.021 14.8 0.0 1.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 KZN90054.1 - 0.012 15.5 0.0 0.031 14.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KZN90054.1 - 0.018 15.1 0.0 0.043 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KZN90054.1 - 0.022 14.9 0.0 0.057 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KZN90054.1 - 0.025 14.3 0.0 0.079 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KZN90054.1 - 0.029 13.7 0.0 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_30 PF13604.6 KZN90054.1 - 0.031 14.0 0.0 0.085 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Prot_ATP_OB_N PF17758.1 KZN90054.1 - 0.04 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain AAA_25 PF13481.6 KZN90054.1 - 0.054 13.1 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain GAS PF13851.6 KZN90054.1 - 0.068 12.5 1.1 0.15 11.4 1.1 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding PhoH PF02562.16 KZN90054.1 - 0.074 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein CEP209_CC5 PF16574.5 KZN90054.1 - 0.079 13.1 1.4 0.26 11.5 1.4 1.8 1 1 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 NACHT PF05729.12 KZN90054.1 - 0.08 12.9 0.1 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 KZN90054.1 - 0.097 12.9 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KZN90054.1 - 0.13 11.4 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 KZN90054.1 - 0.13 12.0 0.1 0.34 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain Glyco_hydro_47 PF01532.20 KZN90055.1 - 2.7e-162 540.8 0.0 3.1e-162 540.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Peptidase_M20 PF01546.28 KZN90056.1 - 9e-16 58.2 0.2 2.7e-14 53.4 0.2 2.2 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KZN90056.1 - 3e-15 56.1 0.0 5.7e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KZN90056.1 - 0.043 13.5 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 Peptidase_M42 PF05343.14 KZN90056.1 - 0.087 11.8 0.0 2 7.3 0.0 2.6 3 0 0 3 3 3 0 M42 glutamyl aminopeptidase NAD_binding_4 PF07993.12 KZN90057.1 - 1.9e-43 148.5 0.0 3.1e-43 147.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KZN90057.1 - 1.6e-29 102.7 0.0 2.9e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KZN90057.1 - 1.8e-11 44.0 0.0 3.4e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KZN90057.1 - 1.3e-06 28.7 0.0 3.6e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KZN90057.1 - 0.00035 19.7 0.0 0.0046 16.0 0.0 2.5 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KZN90057.1 - 0.058 12.5 0.0 5.3 6.1 0.0 2.5 2 0 0 2 2 2 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KZN90057.1 - 0.096 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase KR PF08659.10 KZN90057.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 KZN90057.1 - 0.22 10.6 0.0 1.5 7.9 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Glyco_hydro_42 PF02449.15 KZN90058.1 - 6.6e-111 371.2 1.6 9.1e-111 370.8 1.6 1.1 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_42M PF08532.10 KZN90058.1 - 1.1e-22 80.6 0.0 1.7e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain Glyco_hydro_14 PF01373.17 KZN90058.1 - 0.00027 20.0 0.1 0.00044 19.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 Glyco_hydro_42C PF08533.10 KZN90058.1 - 0.00038 20.1 0.0 0.00076 19.2 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase C-terminal domain Cellulase PF00150.18 KZN90058.1 - 0.0014 18.2 0.1 0.0023 17.4 0.1 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4434 PF14488.6 KZN90058.1 - 0.002 18.2 0.7 0.034 14.2 0.7 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4434) Glyco_hydro_35 PF01301.19 KZN90058.1 - 0.0062 16.2 0.1 0.088 12.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 PNK3P PF08645.11 KZN90060.1 - 4.5e-53 179.3 0.0 7.3e-53 178.6 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 KZN90060.1 - 1.1e-28 100.2 0.0 1.6e-25 89.9 0.0 3.1 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.10 KZN90060.1 - 0.00024 20.6 1.0 0.19 11.2 0.0 2.4 2 1 1 3 3 3 2 Chromatin associated protein KTI12 RsgA_GTPase PF03193.16 KZN90060.1 - 0.19 11.7 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 KZN90060.1 - 0.2 10.9 0.0 1.7 7.9 0.0 2.0 1 1 0 2 2 2 0 Zeta toxin Med18 PF09637.10 KZN90061.1 - 8.8e-62 209.2 0.0 1e-61 209.0 0.0 1.0 1 0 0 1 1 1 1 Med18 protein S36_mt PF10937.8 KZN90062.1 - 9.9e-40 136.7 0.2 1.2e-39 136.5 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial DUF647 PF04884.14 KZN90063.1 - 3e-80 269.3 3.7 5.1e-80 268.6 3.7 1.3 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis RGS PF00615.19 KZN90064.1 - 4.8e-13 49.4 0.0 9.1e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Pkinase PF00069.25 KZN90065.1 - 7.5e-28 97.6 0.0 9.2e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN90065.1 - 1.6e-14 53.9 0.0 2e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KZN90065.1 - 4.4e-07 29.0 0.0 6.5e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Rtt106 PF08512.12 KZN90066.1 - 1.4e-30 105.6 0.1 1.2e-29 102.5 0.0 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PH_18 PF18469.1 KZN90066.1 - 3.5e-05 23.8 0.0 8.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain NPR3 PF03666.13 KZN90066.1 - 6.7 5.4 6.3 10 4.8 6.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 KOW PF00467.29 KZN90067.1 - 0.011 15.6 0.9 0.021 14.7 0.9 1.5 1 0 0 1 1 1 0 KOW motif FAO_M PF16350.5 KZN90067.1 - 0.022 15.1 1.0 0.094 13.1 0.8 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase central domain Ras PF00071.22 KZN90068.1 - 3.7e-56 189.2 0.0 4.5e-56 188.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KZN90068.1 - 5.5e-22 78.2 0.0 8.6e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KZN90068.1 - 3.7e-07 29.8 0.0 6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KZN90068.1 - 0.00062 19.2 0.0 0.00086 18.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KZN90068.1 - 0.0015 18.1 0.0 0.0038 16.8 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KZN90068.1 - 0.058 12.7 0.0 0.077 12.3 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region NB-ARC PF00931.22 KZN90068.1 - 0.069 12.3 0.0 0.69 9.0 0.0 2.0 1 1 1 2 2 2 0 NB-ARC domain DUF1712 PF08217.11 KZN90069.1 - 1.1e-14 53.9 0.0 4.4e-12 45.3 0.0 2.3 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1712) Formyl_trans_N PF00551.19 KZN90070.1 - 2.5e-19 69.7 0.1 3.5e-19 69.3 0.1 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 KZN90070.1 - 0.0086 16.3 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain adh_short_C2 PF13561.6 KZN90071.1 - 2e-41 142.1 0.1 2.5e-41 141.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN90071.1 - 2.1e-37 128.5 0.0 2.9e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN90071.1 - 8.6e-11 42.1 0.1 4.4e-10 39.8 0.1 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KZN90071.1 - 0.0026 17.3 0.0 0.0077 15.7 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family YAcAr PF10686.9 KZN90071.1 - 0.12 12.4 0.1 20 5.2 0.1 2.6 1 1 1 2 2 2 0 YspA, cpYpsA-related SLOG family Alg14 PF08660.11 KZN90072.1 - 1.7e-55 187.6 0.0 2.7e-55 187.0 0.0 1.3 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Ima1_N PF09779.9 KZN90073.1 - 6.3e-33 114.5 4.1 6.3e-33 114.5 4.1 2.4 2 0 0 2 2 2 1 Ima1 N-terminal domain KduI PF04962.12 KZN90073.1 - 0.086 12.1 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 KduI/IolB family Zn_Tnp_IS1595 PF12760.7 KZN90073.1 - 0.17 11.9 7.0 0.022 14.8 2.5 1.9 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF2264 PF10022.9 KZN90074.1 - 4.3e-142 473.4 0.1 5.2e-142 473.1 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) BPL_LplA_LipB PF03099.19 KZN90075.1 - 1.5e-07 31.4 0.0 4.6e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Chorismate_synt PF01264.21 KZN90076.1 - 2.5e-139 463.5 0.0 2.9e-139 463.3 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase KGG PF10685.9 KZN90077.1 - 7.7e-19 67.3 20.8 5.8e-09 35.9 0.7 3.2 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif Hemerythrin PF01814.23 KZN90078.1 - 1.8e-12 48.0 0.3 2.8e-12 47.4 0.3 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Zn_clus PF00172.18 KZN90080.1 - 2.2e-06 27.7 9.4 4.4e-06 26.7 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BIR PF00653.21 KZN90082.1 - 0.018 15.7 0.1 0.037 14.7 0.1 1.5 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain DUF3330 PF11809.8 KZN90086.1 - 0.0028 17.7 0.0 0.0084 16.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3330) zf-RING_2 PF13639.6 KZN90086.1 - 0.0079 16.5 8.4 0.018 15.4 8.4 1.6 1 0 0 1 1 1 1 Ring finger domain RINGv PF12906.7 KZN90086.1 - 0.11 12.7 9.0 0.22 11.7 9.0 1.6 1 0 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 KZN90086.1 - 0.36 10.5 7.3 0.97 9.1 7.3 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Ank_2 PF12796.7 KZN90087.1 - 1.5e-21 76.8 1.2 6.1e-11 42.7 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KZN90087.1 - 3.3e-18 63.9 1.9 0.0009 19.5 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KZN90087.1 - 1.5e-17 63.4 1.9 3.8e-05 23.9 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KZN90087.1 - 2.9e-17 62.2 5.4 2.2e-06 27.8 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KZN90087.1 - 1.8e-13 50.7 5.3 8.6e-06 26.2 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) F-box-like PF12937.7 KZN90087.1 - 5.2e-06 26.3 0.2 8.7e-06 25.5 0.2 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN90087.1 - 2.4e-05 24.1 0.2 4.2e-05 23.3 0.2 1.4 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KZN90087.1 - 0.11 12.4 0.1 0.22 11.4 0.1 1.5 1 1 0 1 1 1 0 F-box DUF4347 PF14252.6 KZN90088.1 - 0.11 12.4 0.1 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4347) Hydrolase PF00702.26 KZN90091.1 - 9.5e-17 62.0 0.0 1.5e-16 61.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KZN90091.1 - 6.2e-07 29.4 0.1 0.0086 15.8 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KZN90091.1 - 0.0024 18.3 0.0 0.0031 18.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase CmcI PF04989.12 KZN90091.1 - 0.1 12.3 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase ACP_syn_III_C PF08541.10 KZN90091.1 - 0.1 12.8 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF3292 PF11696.8 KZN90092.1 - 2e-255 849.2 0.0 2e-212 707.2 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3292) DUF4229 PF14012.6 KZN90092.1 - 3.8 7.7 6.1 2.7 8.1 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) FUSC PF04632.12 KZN90094.1 - 0.83 8.1 3.2 0.93 7.9 3.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family MAP7 PF05672.11 KZN90094.1 - 1.9 8.2 12.4 2.4 7.8 12.4 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family FAA_hydro_N_2 PF18288.1 KZN90094.1 - 2.2 8.8 4.7 2.7 8.5 0.2 2.3 1 1 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 Flagellar_rod PF05149.12 KZN90094.1 - 2.2 7.7 10.2 2.9 7.3 10.2 1.1 1 0 0 1 1 1 0 Paraflagellar rod protein POTRA_TamA_1 PF17243.2 KZN90094.1 - 3.6 7.7 5.4 1.1 9.5 1.8 1.9 1 1 1 2 2 2 0 POTRA domain TamA domain 1 Glyco_hydro_61 PF03443.14 KZN90096.1 - 0.029 14.3 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 DUF4625 PF15418.6 KZN90096.1 - 0.052 13.8 0.0 0.08 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) Patatin PF01734.22 KZN90098.1 - 1.9e-20 73.9 1.1 3.5e-20 73.1 0.3 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase zf-C3HC4_3 PF13920.6 KZN90098.1 - 2.7e-05 23.9 6.1 6.8e-05 22.6 6.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KZN90098.1 - 0.0011 18.7 5.8 0.0039 17.0 5.8 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KZN90098.1 - 0.0014 18.5 5.2 0.0055 16.6 5.3 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KZN90098.1 - 0.0087 16.0 7.2 0.027 14.4 7.2 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KZN90098.1 - 0.15 12.4 8.7 0.53 10.7 8.7 2.1 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 KZN90098.1 - 1.1 9.2 8.0 1.1 9.2 4.1 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KZN90098.1 - 4.6 7.4 11.1 1.8 8.6 4.9 2.9 2 0 0 2 2 2 0 RING-type zinc-finger DUF2841 PF11001.8 KZN90101.1 - 4.3e-45 152.8 0.5 6.3e-45 152.2 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Nucleo_P87 PF07267.11 KZN90102.1 - 0.85 8.4 3.0 1.1 8.0 3.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FUSC PF04632.12 KZN90103.1 - 0.18 10.3 5.4 0.2 10.1 5.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family OmpH PF03938.14 KZN90103.1 - 0.22 11.8 10.8 0.32 11.3 10.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4795 PF16043.5 KZN90103.1 - 0.56 9.8 9.9 4.4 6.9 5.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) FapA PF03961.13 KZN90103.1 - 0.6 8.7 2.5 0.7 8.4 2.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A YabA PF06156.13 KZN90104.1 - 0.007 17.0 0.2 0.012 16.2 0.2 1.4 1 0 0 1 1 1 1 Initiation control protein YabA Spc7 PF08317.11 KZN90104.1 - 0.017 14.1 0.3 0.02 13.8 0.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein IFT57 PF10498.9 KZN90104.1 - 0.021 13.8 0.1 0.023 13.7 0.1 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CASP_C PF08172.12 KZN90104.1 - 0.085 12.2 2.2 0.32 10.3 0.7 2.1 1 1 0 2 2 2 0 CASP C terminal Uso1_p115_C PF04871.13 KZN90104.1 - 0.097 13.0 0.4 0.14 12.5 0.4 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region HALZ PF02183.18 KZN90104.1 - 0.12 12.6 1.1 0.55 10.5 0.3 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper zf-H2C2_2 PF13465.6 KZN90106.1 - 7.3e-18 64.1 20.5 5.9e-06 26.5 0.1 4.9 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.26 KZN90106.1 - 2.3e-15 56.1 37.4 0.00014 22.1 7.8 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KZN90106.1 - 7.9e-05 23.2 34.1 0.14 13.0 0.8 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KZN90106.1 - 0.023 15.0 4.9 5.2 7.5 0.0 3.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Epimerase PF01370.21 KZN90107.1 - 0.0036 16.8 0.0 0.0036 16.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KZN90107.1 - 0.0067 16.0 0.0 0.0076 15.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KZN90107.1 - 0.015 14.7 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KZN90107.1 - 0.016 15.1 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding adh_short PF00106.25 KZN90107.1 - 0.088 12.2 0.0 0.099 12.1 0.0 1.0 1 0 0 1 1 1 0 short chain dehydrogenase bZIP_1 PF00170.21 KZN90108.1 - 2.5e-07 30.7 12.1 8.5e-07 29.0 12.1 1.9 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KZN90108.1 - 0.00018 22.0 8.7 0.00018 22.0 8.7 2.2 2 0 0 2 2 2 1 bZIP Maf transcription factor dsrm PF00035.26 KZN90108.1 - 0.0022 18.7 0.6 0.0039 17.9 0.6 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif bZIP_2 PF07716.15 KZN90108.1 - 0.36 11.0 22.5 0.045 13.8 16.0 2.6 2 1 0 2 2 2 0 Basic region leucine zipper DUF4407 PF14362.6 KZN90108.1 - 7.1 5.9 8.6 7.9 5.7 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RRM_1 PF00076.22 KZN90109.1 - 4e-07 29.7 0.0 6.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KZN90109.1 - 0.08 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cadherin_tail PF15974.5 KZN90110.1 - 0.097 13.0 0.1 0.1 12.9 0.1 1.1 1 0 0 1 1 1 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region CP2 PF04516.15 KZN90111.1 - 1.1e-73 247.4 0.0 1.7e-73 246.7 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor DUF3394 PF11874.8 KZN90111.1 - 0.083 12.6 0.0 0.9 9.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3394) DUF3723 PF12520.8 KZN90112.1 - 2e-60 205.0 0.0 3.2e-60 204.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) Ferritin PF00210.24 KZN90113.1 - 1.3e-12 47.8 0.0 1.8e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Ferritin-like domain Phospholamban PF04272.14 KZN90114.1 - 0.0082 15.6 0.1 0.02 14.4 0.1 1.6 1 0 0 1 1 1 1 Phospholamban DNA_pol_alpha_N PF12254.8 KZN90114.1 - 0.095 12.8 0.2 0.2 11.8 0.2 1.5 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal bZIP_1 PF00170.21 KZN90115.1 - 3.9e-08 33.3 8.3 6.3e-08 32.6 8.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KZN90115.1 - 1.5e-05 24.9 8.8 2.6e-05 24.2 8.8 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KZN90115.1 - 0.16 12.5 7.4 0.12 12.9 5.7 1.7 1 1 0 1 1 1 0 bZIP Maf transcription factor bZIP_1 PF00170.21 KZN90116.1 - 7.6e-06 25.9 7.7 1.7e-05 24.8 7.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KZN90116.1 - 3.2e-05 23.9 5.7 6.2e-05 23.0 5.7 1.4 1 0 0 1 1 1 1 Basic region leucine zipper Phage_TAC_6 PF09550.10 KZN90117.1 - 0.011 16.2 0.1 0.024 15.0 0.1 1.5 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC Thioredoxin_4 PF13462.6 KZN90117.1 - 0.028 14.6 0.0 0.036 14.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DUF4686 PF15742.5 KZN90120.1 - 0.0035 16.5 11.7 0.0044 16.2 11.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) FUSC PF04632.12 KZN90120.1 - 1.3 7.5 4.6 1.5 7.2 4.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family MAP7 PF05672.11 KZN90120.1 - 2.5 7.8 13.8 3.9 7.1 13.8 1.3 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Glyco_hydro_61 PF03443.14 KZN90122.1 - 0.0034 17.3 0.0 0.0051 16.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4625 PF15418.6 KZN90122.1 - 0.0043 17.3 0.0 0.0088 16.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4625) Phage_holin_3_3 PF16083.5 KZN90123.1 - 0.19 11.9 2.9 0.39 10.9 1.7 2.1 2 1 0 2 2 2 0 LydA holin phage, holin superfamily III Patatin PF01734.22 KZN90124.1 - 3.7e-21 76.2 0.7 2.4e-20 73.6 0.3 2.5 3 0 0 3 3 3 1 Patatin-like phospholipase zf-C3HC4_3 PF13920.6 KZN90124.1 - 3.7e-05 23.5 6.2 0.0001 22.1 6.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KZN90124.1 - 0.0017 18.2 7.0 0.0073 16.1 7.0 2.1 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KZN90124.1 - 0.008 16.0 8.4 0.029 14.2 8.4 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KZN90124.1 - 0.0098 15.8 7.4 0.031 14.2 7.4 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KZN90124.1 - 0.16 12.3 9.2 0.59 10.5 9.2 2.1 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 KZN90124.1 - 0.55 10.1 7.2 0.76 9.7 3.7 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) EF-hand_14 PF17959.1 KZN90125.1 - 0.089 13.2 0.1 1.3 9.5 0.1 2.2 2 0 0 2 2 2 0 EF-hand domain BAR_2 PF10455.9 KZN90126.1 - 0.03 13.5 0.1 0.045 12.9 0.1 1.2 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF3723 PF12520.8 KZN90129.1 - 6.9e-49 166.9 0.5 3.1e-28 98.7 0.1 3.7 2 1 1 3 3 3 3 Protein of unknown function (DUF3723) Metaviral_G PF09595.10 KZN90129.1 - 0.038 14.1 0.1 0.065 13.3 0.1 1.2 1 0 0 1 1 1 0 Metaviral_G glycoprotein DUF1129 PF06570.11 KZN90130.1 - 0.1 12.0 2.2 0.16 11.4 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Spc7 PF08317.11 KZN90132.1 - 0.0021 17.0 2.8 0.0031 16.4 2.8 1.4 1 1 0 1 1 1 1 Spc7 kinetochore protein YabA PF06156.13 KZN90132.1 - 0.0034 18.0 0.3 0.0069 17.0 0.3 1.5 1 0 0 1 1 1 1 Initiation control protein YabA Rootletin PF15035.6 KZN90132.1 - 0.0041 17.2 0.2 0.0061 16.6 0.2 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.9 KZN90132.1 - 0.0075 16.3 1.1 0.013 15.5 1.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cnn_1N PF07989.11 KZN90132.1 - 0.0094 16.1 1.3 0.02 15.0 1.3 1.6 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 Fez1 PF06818.15 KZN90132.1 - 0.0097 16.4 0.2 0.016 15.7 0.2 1.3 1 0 0 1 1 1 1 Fez1 ADIP PF11559.8 KZN90132.1 - 0.012 15.7 0.9 0.022 14.8 0.9 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding KASH_CCD PF14662.6 KZN90132.1 - 0.013 15.3 0.8 0.021 14.6 0.8 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 KZN90132.1 - 0.015 14.6 0.4 0.026 13.9 0.4 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CASP_C PF08172.12 KZN90132.1 - 0.018 14.4 0.1 0.024 14.0 0.1 1.3 1 0 0 1 1 1 0 CASP C terminal DUF4200 PF13863.6 KZN90132.1 - 0.022 15.2 0.6 0.047 14.1 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Uso1_p115_C PF04871.13 KZN90132.1 - 0.026 14.9 0.9 0.043 14.2 0.9 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region PEPcase PF00311.17 KZN90132.1 - 0.028 12.5 0.1 0.031 12.4 0.1 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase HIP1_clath_bdg PF16515.5 KZN90132.1 - 0.029 15.0 0.2 0.063 13.9 0.2 1.5 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 HALZ PF02183.18 KZN90132.1 - 0.034 14.4 0.9 0.14 12.4 0.3 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper DNA_repr_REX1B PF14966.6 KZN90132.1 - 0.048 14.3 0.5 0.19 12.4 0.0 2.2 3 0 0 3 3 2 0 DNA repair REX1-B TMPIT PF07851.13 KZN90132.1 - 0.087 12.1 0.3 0.13 11.5 0.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein TPR_MLP1_2 PF07926.12 KZN90132.1 - 0.096 12.8 3.1 0.29 11.2 0.5 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1640 PF07798.11 KZN90132.1 - 0.1 12.7 3.0 8.4 6.4 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) DUF1664 PF07889.12 KZN90132.1 - 0.15 12.1 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Prominin PF05478.11 KZN90132.1 - 0.18 9.7 0.3 0.23 9.4 0.3 1.1 1 0 0 1 1 1 0 Prominin Mto2_bdg PF12808.7 KZN90132.1 - 0.56 10.5 0.1 0.56 10.5 0.1 3.0 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region BRE1 PF08647.11 KZN90132.1 - 1.4 9.0 5.1 0.22 11.6 0.4 1.8 2 1 0 2 2 1 0 BRE1 E3 ubiquitin ligase DUF4795 PF16043.5 KZN90133.1 - 0.22 11.1 9.3 3.6 7.1 9.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) OmpH PF03938.14 KZN90133.1 - 0.38 11.1 6.7 0.53 10.6 6.7 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FUSC PF04632.12 KZN90133.1 - 0.95 7.9 6.7 1.2 7.6 6.7 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family APH PF01636.23 KZN90135.1 - 1e-09 38.7 0.0 4.6e-09 36.5 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KZN90135.1 - 0.2 10.9 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase PP1c_bdg PF10488.9 KZN90137.1 - 0.0086 15.6 0.6 0.0086 15.6 0.6 1.6 2 0 0 2 2 2 1 Phosphatase-1 catalytic subunit binding region Ank_2 PF12796.7 KZN90139.1 - 1.8e-22 79.7 0.9 5.1e-11 43.0 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN90139.1 - 1.6e-14 54.0 0.2 1.4e-07 32.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN90139.1 - 9.5e-13 47.1 0.3 0.0004 20.6 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 KZN90139.1 - 7.2e-11 42.0 0.3 2.1e-05 24.7 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KZN90139.1 - 1.1e-10 41.5 1.6 2.5e-07 30.8 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KZN90140.1 - 2.8e-15 56.5 0.1 5.4e-06 26.8 0.0 4.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KZN90140.1 - 2.4e-11 44.1 0.0 0.00014 22.4 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KZN90140.1 - 8.1e-10 38.8 0.0 0.0019 18.5 0.0 3.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN90140.1 - 4.2e-09 35.9 0.0 0.11 13.2 0.0 4.5 3 1 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KZN90140.1 - 6e-09 36.0 0.0 0.33 11.5 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Zn_clus PF00172.18 KZN90141.1 - 5.4e-09 36.0 12.3 1.1e-08 35.1 12.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dimer_Tnp_hAT PF05699.14 KZN90142.1 - 2.9e-08 33.4 0.0 7.8e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KZN90142.1 - 0.00038 20.8 0.7 0.0099 16.2 0.0 3.0 2 2 1 3 3 3 1 Domain of unknown function (DUF4413) DUF4763 PF15960.5 KZN90143.1 - 0.024 13.9 0.4 0.04 13.2 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) GLE1 PF07817.13 KZN90143.1 - 0.19 10.9 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 GLE1-like protein Methyltransf_23 PF13489.6 KZN90144.1 - 3.2e-07 30.3 0.0 5.7e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN90144.1 - 0.00015 21.6 0.0 0.00022 21.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN90144.1 - 0.00084 20.0 0.0 0.0016 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN90144.1 - 0.00099 19.7 0.0 0.0017 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ras PF00071.22 KZN90145.1 - 7.9e-38 129.6 0.0 2e-37 128.3 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KZN90145.1 - 6e-13 49.1 0.0 7.1e-12 45.6 0.0 2.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KZN90145.1 - 0.0013 18.8 0.0 0.0021 18.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase zf-C2H2_10 PF16588.5 KZN90146.1 - 0.0033 17.1 1.5 0.0053 16.4 1.5 1.3 1 0 0 1 1 1 1 C2H2 zinc-finger zf-CCHC PF00098.23 KZN90146.1 - 0.075 13.1 2.3 0.16 12.1 2.3 1.5 1 0 0 1 1 1 0 Zinc knuckle V_ATPase_I PF01496.19 KZN90146.1 - 0.19 9.6 0.2 0.25 9.2 0.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family JSRP PF15312.6 KZN90147.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein DUF4219 PF13961.6 KZN90148.1 - 9.8e-10 37.9 0.1 1.6e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 KZN90148.1 - 2e-07 30.7 0.0 3.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Flavi_NS5 PF00972.20 KZN90150.1 - 0.13 10.3 0.1 0.15 10.1 0.1 1.0 1 0 0 1 1 1 0 Flavivirus RNA-directed RNA polymerase Zn_clus PF00172.18 KZN90151.1 - 6.3e-08 32.6 10.3 1.4e-07 31.5 10.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2841 PF11001.8 KZN90152.1 - 1.7e-42 144.4 0.8 1.7e-42 144.4 0.8 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) Cyclin PF08613.11 KZN90153.1 - 1.4e-10 41.8 0.0 2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KZN90153.1 - 1.9e-09 37.3 0.0 3.5e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Hydrolase PF00702.26 KZN90154.1 - 1.7e-11 44.8 0.0 2.2e-10 41.2 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KZN90154.1 - 1.7e-08 34.4 0.3 1.7e-08 34.4 0.3 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KZN90154.1 - 4.7e-08 33.0 0.0 9.7e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KZN90154.1 - 9.9e-06 25.2 1.6 1.7e-05 24.4 1.6 1.3 1 0 0 1 1 1 1 E1-E2 ATPase DUF4381 PF14316.6 KZN90154.1 - 0.082 13.1 0.3 0.22 11.8 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) Hydrolase_3 PF08282.12 KZN90154.1 - 0.089 12.5 0.5 0.18 11.5 0.5 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HSF_DNA-bind PF00447.17 KZN90159.1 - 1.4e-11 44.9 0.0 2.8e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding CnrY PF17524.2 KZN90159.1 - 0.17 12.1 0.4 0.44 10.8 0.4 1.6 1 0 0 1 1 1 0 Anti-sigma factor CnrY Syntaxin-6_N PF09177.11 KZN90159.1 - 3.4 8.3 6.5 15 6.2 1.5 2.6 3 0 0 3 3 3 0 Syntaxin 6, N-terminal zf-H2C2_2 PF13465.6 KZN90160.1 - 0.0019 18.6 0.1 0.0019 18.6 0.1 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KZN90160.1 - 0.016 16.0 4.5 0.95 10.5 2.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KZN90160.1 - 0.02 15.3 7.3 0.95 10.1 2.6 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type RNA_pol_I_TF PF04090.12 KZN90160.1 - 0.055 13.0 0.0 0.074 12.5 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific initiation factor Methyltransf_23 PF13489.6 KZN90161.1 - 1.2e-14 54.4 0.0 2.1e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN90161.1 - 2e-07 31.6 0.0 7.7e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN90161.1 - 0.0018 18.9 0.0 0.0055 17.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN90161.1 - 0.0018 18.1 0.0 0.0074 16.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN90161.1 - 0.0082 16.9 0.0 0.17 12.7 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 KZN90161.1 - 0.014 14.9 0.2 0.063 12.8 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.14 KZN90161.1 - 0.039 13.5 0.0 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_2 PF00891.18 KZN90161.1 - 0.048 12.9 0.0 0.5 9.6 0.0 2.0 2 0 0 2 2 2 0 O-methyltransferase domain PrmA PF06325.13 KZN90161.1 - 0.11 11.9 0.0 4.1 6.7 0.0 2.3 1 1 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KZN90161.1 - 0.12 11.7 0.0 7.1 5.9 0.0 2.5 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Retrotran_gag_2 PF14223.6 KZN90163.1 - 1.1e-13 51.0 0.0 1.9e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KZN90163.1 - 1.4e-09 37.4 0.1 3.1e-09 36.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 KZN90163.1 - 1.1e-06 28.4 0.0 2.3e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type SF1-HH PF16275.5 KZN90163.1 - 0.071 13.5 0.2 0.14 12.5 0.2 1.4 1 0 0 1 1 1 0 Splicing factor 1 helix-hairpin domain zf-C2H2_10 PF16588.5 KZN90163.1 - 0.18 11.6 0.3 0.35 10.6 0.3 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger Molybdopterin PF00384.22 KZN90164.1 - 3.9e-64 217.2 0.0 5.6e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 KZN90164.1 - 1.7e-28 98.9 0.0 3.8e-28 97.7 0.0 1.6 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 KZN90164.1 - 1.6e-12 47.2 1.0 4.2e-12 45.9 0.5 2.0 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Fe4S4 domain DUF3431 PF11913.8 KZN90165.1 - 1e-24 87.5 0.0 1.4e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Caleosin PF05042.13 KZN90167.1 - 1.1e-74 250.0 0.3 1.4e-74 249.7 0.3 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_1 PF00036.32 KZN90167.1 - 2.6e-05 23.5 5.3 0.00014 21.1 0.1 3.4 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.6 KZN90167.1 - 0.00011 21.8 8.1 0.00023 20.8 0.3 3.5 4 0 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.6 KZN90167.1 - 0.0033 17.2 0.1 0.077 12.9 0.1 2.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.6 KZN90167.1 - 0.0055 17.1 1.1 0.055 13.9 0.6 2.6 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KZN90167.1 - 0.014 14.8 0.4 0.014 14.8 0.4 3.6 4 0 0 4 4 4 0 EF hand Hyr1 PF15789.5 KZN90168.1 - 0.7 9.5 2.8 2.2 7.9 0.5 2.5 2 0 0 2 2 2 0 Hyphally regulated cell wall GPI-anchored protein 1 NmrA PF05368.13 KZN90169.1 - 7.1e-26 91.2 0.0 1.2e-25 90.4 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KZN90169.1 - 2.3e-15 57.0 0.0 3.3e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KZN90169.1 - 9.7e-05 22.8 0.1 0.00016 22.1 0.1 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KZN90169.1 - 0.0014 17.7 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KZN90169.1 - 0.0016 17.7 0.0 0.0023 17.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 KZN90169.1 - 0.0019 18.5 0.0 0.0033 17.7 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KZN90169.1 - 0.032 13.7 0.0 0.055 12.9 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KZN90169.1 - 0.034 14.3 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.16 KZN90169.1 - 0.071 13.8 0.1 0.5 11.1 0.0 2.2 2 1 1 3 3 3 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase F420_oxidored PF03807.17 KZN90169.1 - 0.089 13.4 0.1 0.17 12.5 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ank_2 PF12796.7 KZN90170.1 - 6.6e-36 122.8 5.2 4.6e-14 52.8 0.0 3.6 2 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN90170.1 - 1.6e-29 101.9 6.0 4.1e-09 36.8 0.1 5.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN90170.1 - 3.4e-24 82.3 6.0 0.00065 20.0 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KZN90170.1 - 2.1e-22 78.9 9.3 3.1e-08 33.7 0.0 6.6 2 2 5 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 KZN90170.1 - 3.1e-16 59.0 13.6 0.001 19.4 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat ACT PF01842.25 KZN90170.1 - 0.12 12.2 0.1 27 4.7 0.0 3.4 3 0 0 3 3 3 0 ACT domain HeLo PF14479.6 KZN90171.1 - 2.6e-36 125.4 0.2 3.8e-36 124.9 0.2 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.17 KZN90171.1 - 0.0012 18.2 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Transferase PF02458.15 KZN90173.1 - 5.4e-16 58.3 0.0 7.2e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 Transferase family OrsD PF12013.8 KZN90174.1 - 1.5e-08 35.0 0.2 2.5e-08 34.4 0.2 1.4 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D Helo_like_N PF17111.5 KZN90176.1 - 2.5e-23 82.5 0.1 4e-23 81.9 0.1 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins APH PF01636.23 KZN90176.1 - 6.3e-11 42.7 0.1 7.1e-10 39.2 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN90176.1 - 4.9e-10 39.3 0.0 1e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Flagellin_N PF00669.20 KZN90176.1 - 0.031 14.4 0.9 0.045 13.9 0.1 1.6 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region Pkinase PF00069.25 KZN90176.1 - 0.084 12.2 0.0 9.7 5.5 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain Glyco_hydro_31 PF01055.26 KZN90177.1 - 7.7e-113 378.0 2.7 9.5e-113 377.7 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 KZN90177.1 - 2.9e-05 24.3 0.0 5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Gal_mutarotas_2 PF13802.6 KZN90177.1 - 0.0011 19.3 2.9 0.0099 16.2 0.1 2.9 3 1 0 3 3 3 1 Galactose mutarotase-like UPF0449 PF15136.6 KZN90177.1 - 0.14 12.7 0.0 1.7 9.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 APH PF01636.23 KZN90178.1 - 5e-14 52.8 0.0 7.4e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN90178.1 - 0.0031 17.1 0.0 0.0053 16.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 KZN90178.1 - 0.15 10.9 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) NCBP3 PF10309.9 KZN90179.1 - 1.7e-20 72.6 0.0 2.6e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 LisH PF08513.11 KZN90180.1 - 0.00036 20.4 0.0 0.00074 19.4 0.0 1.5 1 0 0 1 1 1 1 LisH ANAPC4_WD40 PF12894.7 KZN90180.1 - 0.031 14.6 0.0 0.17 12.2 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L29e PF01779.17 KZN90181.1 - 3.6e-21 75.2 9.7 6.2e-21 74.4 9.7 1.4 1 0 0 1 1 1 1 Ribosomal L29e protein family ATP-synt_DE_N PF02823.16 KZN90182.1 - 2.8e-17 62.4 0.0 4.1e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Cytochrom_B561 PF03188.16 KZN90184.1 - 0.00033 20.8 7.4 0.00072 19.7 7.2 1.7 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF21 PF01595.20 KZN90184.1 - 0.13 12.0 0.3 0.29 10.8 0.3 1.5 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain PQ-loop PF04193.14 KZN90185.1 - 1.6e-33 114.3 13.4 5.9e-18 64.4 1.7 2.5 2 0 0 2 2 2 2 PQ loop repeat FOXP-CC PF16159.5 KZN90186.1 - 0.00034 21.2 0.8 0.039 14.6 0.0 2.7 2 0 0 2 2 2 1 FOXP coiled-coil domain zf-C2H2 PF00096.26 KZN90186.1 - 0.052 14.0 6.4 0.11 13.1 0.1 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KZN90186.1 - 0.11 13.4 7.9 0.95 10.5 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger CxC6 PF18721.1 KZN90186.1 - 2.6 8.4 5.6 1.6 9.0 3.4 1.7 1 1 1 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases Abhydrolase_6 PF12697.7 KZN90187.1 - 0.00093 19.9 0.0 0.0013 19.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 KZN90187.1 - 0.0012 18.5 0.0 0.0036 16.9 0.0 1.8 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KZN90187.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.4 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.20 KZN90187.1 - 0.012 15.2 0.1 0.019 14.6 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold zf-C2H2 PF00096.26 KZN90188.1 - 3.9e-08 33.3 13.4 0.0051 17.2 2.0 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KZN90188.1 - 0.00019 21.7 10.9 0.67 10.5 0.2 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KZN90188.1 - 0.047 14.5 13.9 0.11 13.4 1.8 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-Di19 PF05605.12 KZN90188.1 - 0.9 9.9 8.6 0.28 11.5 1.1 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding APH PF01636.23 KZN90189.1 - 3.1e-40 138.6 0.0 5.5e-40 137.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KZN90189.1 - 0.00019 20.8 0.0 0.00049 19.5 0.0 1.7 1 1 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 KZN90189.1 - 0.0016 18.1 0.0 0.24 11.0 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Kdo PF06293.14 KZN90189.1 - 0.0022 17.4 0.0 0.011 15.1 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KZN90189.1 - 0.0053 16.4 0.0 0.008 15.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 KZN90189.1 - 0.029 13.6 0.0 0.46 9.6 0.0 2.2 1 1 0 1 1 1 0 Fructosamine kinase dUTPase PF00692.19 KZN90190.1 - 2.6e-44 150.0 0.0 3.2e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 dUTPase DCD PF06559.11 KZN90190.1 - 0.072 11.9 0.0 0.095 11.5 0.0 1.1 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) Phos_pyr_kin PF08543.12 KZN90191.1 - 7.6e-13 48.4 0.0 2.7e-12 46.6 0.0 1.7 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KZN90191.1 - 5.5e-06 25.9 0.6 5.9e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 pfkB family carbohydrate kinase StbA PF06406.11 KZN90191.1 - 0.048 12.9 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 StbA protein Afi1 PF07792.12 KZN90193.1 - 2.4e-44 151.0 0.4 4.7e-44 150.1 0.4 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 KZN90193.1 - 1.5e-38 131.3 0.0 2.4e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 KZN90193.1 - 8.5e-10 37.9 0.0 0.0029 16.4 0.0 4.0 3 1 1 4 4 4 3 Transport protein Avl9 DUF2347 PF09804.9 KZN90193.1 - 0.038 13.6 0.0 0.13 11.8 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) HEAT PF02985.22 KZN90193.1 - 0.14 12.4 0.0 0.85 10.1 0.0 2.3 1 0 0 1 1 1 0 HEAT repeat EF-hand_6 PF13405.6 KZN90194.1 - 1.5e-12 46.4 3.8 6.4e-06 25.7 0.3 3.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 KZN90194.1 - 8.1e-11 40.7 3.4 1.4e-05 24.3 0.3 2.7 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KZN90194.1 - 3.9e-08 33.6 2.4 1.8e-07 31.5 1.1 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KZN90194.1 - 8.7e-06 25.0 6.4 0.018 14.5 1.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KZN90194.1 - 1.8e-05 24.5 0.7 0.027 14.3 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KZN90194.1 - 0.0042 17.4 0.1 0.12 12.8 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain RabGAP-TBC PF00566.18 KZN90195.1 - 8.2e-28 97.5 0.0 2.1e-23 83.1 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain MAP65_ASE1 PF03999.12 KZN90195.1 - 0.7 8.5 3.4 0.97 8.0 3.4 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) p450 PF00067.22 KZN90196.1 - 0.00026 19.9 1.2 0.00047 19.0 0.4 1.8 2 1 0 2 2 2 1 Cytochrome P450 RRM_1 PF00076.22 KZN90197.1 - 6.9e-13 48.2 0.0 4e-08 33.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KZN90197.1 - 0.015 14.9 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glucosamine_iso PF01182.20 KZN90198.1 - 9e-67 225.2 0.0 1e-66 225.0 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Thionin PF00321.17 KZN90199.1 - 0.00049 20.5 2.0 0.0006 20.2 2.0 1.1 1 0 0 1 1 1 1 Plant thionin Hom_end PF05204.14 KZN90199.1 - 0.0086 16.2 0.1 0.0093 16.1 0.1 1.0 1 0 0 1 1 1 1 Homing endonuclease Conotoxin PF02950.17 KZN90200.1 - 1.9 9.6 14.3 0.35 11.9 7.9 2.0 1 1 1 2 2 2 0 Conotoxin WD40 PF00400.32 KZN90201.1 - 1.5e-10 41.4 14.6 0.0016 19.2 0.1 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN90201.1 - 0.0024 18.1 0.2 2.1 8.7 0.0 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KZN90201.1 - 0.01 15.2 0.0 1.3 8.3 0.0 3.0 2 1 1 3 3 3 0 WD40-like domain WD40 PF00400.32 KZN90202.1 - 4.5e-22 77.9 12.0 4.3e-06 27.4 0.2 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN90202.1 - 0.0011 19.2 0.0 0.07 13.4 0.0 3.2 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Lebercilin PF15619.6 KZN90202.1 - 0.0076 15.9 1.0 0.018 14.7 1.0 1.6 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease SET PF00856.28 KZN90203.1 - 3.4e-09 37.3 0.0 1.7e-08 35.0 0.0 2.2 2 1 0 2 2 2 1 SET domain TPR_9 PF13371.6 KZN90203.1 - 0.069 13.3 0.3 0.21 11.7 0.3 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-MYND PF01753.18 KZN90203.1 - 0.076 13.1 3.5 0.19 11.9 3.5 1.7 1 0 0 1 1 1 0 MYND finger MA3 PF02847.17 KZN90204.1 - 2.5e-29 101.5 0.2 7.4e-29 100.0 0.1 1.9 2 0 0 2 2 2 1 MA3 domain RPN2_C PF18004.1 KZN90204.1 - 7.8 6.4 8.4 5.8 6.8 1.8 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain DPM2 PF07297.12 KZN90205.1 - 2.2e-31 108.0 1.7 2.6e-31 107.8 1.7 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 KZN90205.1 - 0.00017 21.5 0.8 0.00022 21.1 0.8 1.1 1 0 0 1 1 1 1 PIG-P DUF1772 PF08592.11 KZN90205.1 - 0.046 14.0 0.5 0.05 13.9 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Phage_holin_3_6 PF07332.11 KZN90205.1 - 0.057 13.5 1.2 0.067 13.2 1.2 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III LapA_dom PF06305.11 KZN90205.1 - 0.11 12.3 0.1 0.11 12.3 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain ResIII PF04851.15 KZN90207.1 - 2.6e-21 76.4 0.0 5.1e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KZN90207.1 - 1.8e-20 73.3 0.1 7.4e-20 71.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KZN90207.1 - 1.5e-16 60.7 0.0 4.7e-16 59.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KZN90207.1 - 0.018 14.7 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase AAA_22 PF13401.6 KZN90207.1 - 0.024 14.9 0.0 0.064 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain SPX PF03105.19 KZN90208.1 - 0.17 11.8 6.1 0.17 11.7 6.1 1.0 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 KZN90208.1 - 0.96 8.6 10.3 1 8.5 10.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Plasmodium_Vir PF05795.11 KZN90208.1 - 0.97 8.8 7.8 1.2 8.5 7.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Presenilin PF01080.17 KZN90208.1 - 4.3 6.0 5.0 4.9 5.8 5.0 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 KZN90208.1 - 7.8 4.9 9.2 7.6 5.0 9.2 1.1 1 0 0 1 1 1 0 Macoilin family HD PF01966.22 KZN90209.1 - 6.6e-05 23.1 0.4 0.00021 21.5 0.2 1.9 2 1 0 2 2 2 1 HD domain F_actin_cap_B PF01115.17 KZN90210.1 - 3.5e-106 354.2 0.0 4.1e-106 354.0 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit F-actin_cap_A PF01267.17 KZN90210.1 - 0.091 12.2 0.0 0.3 10.5 0.0 1.8 1 1 0 1 1 1 0 F-actin capping protein alpha subunit Med11 PF10280.9 KZN90211.1 - 2e-38 131.9 0.1 2.6e-38 131.6 0.1 1.2 1 0 0 1 1 1 1 Mediator complex protein DUF1385 PF07136.11 KZN90211.1 - 0.077 12.3 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) WD40 PF00400.32 KZN90212.1 - 2.6e-41 138.8 28.2 4.5e-08 33.6 0.6 6.8 6 1 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KZN90212.1 - 1.8e-39 134.9 0.2 2.7e-39 134.4 0.2 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KZN90212.1 - 2.7e-10 40.4 0.6 0.1 12.9 0.0 5.2 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KZN90212.1 - 4.3e-06 25.7 5.0 0.0021 16.8 0.1 3.3 3 0 0 3 3 3 2 Nucleoporin Nup120/160 LisH PF08513.11 KZN90212.1 - 0.00094 19.1 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 LisH Nbas_N PF15492.6 KZN90212.1 - 0.0072 15.7 0.5 1.1 8.5 0.2 3.0 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.11 KZN90212.1 - 0.022 14.6 0.2 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF4550 PF15084.6 KZN90212.1 - 0.023 15.1 0.1 0.16 12.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4550) DUF4106 PF13388.6 KZN90212.1 - 0.029 13.6 9.2 0.073 12.3 9.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) RAB3GAP2_N PF14655.6 KZN90212.1 - 0.17 11.1 0.1 4.1 6.6 0.0 2.8 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Abhydrolase_6 PF12697.7 KZN90213.1 - 6.9e-23 82.4 0.5 1e-22 81.8 0.1 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KZN90213.1 - 1.7e-06 27.9 0.0 3.7e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KZN90213.1 - 0.017 14.4 0.0 0.045 13.0 0.0 1.7 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KZN90213.1 - 0.08 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 KZN90213.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.7 KZN90213.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme RNase_T PF00929.24 KZN90214.1 - 0.011 16.2 0.1 2.7 8.5 0.0 2.5 2 1 0 3 3 3 0 Exonuclease Cwf_Cwc_15 PF04889.12 KZN90215.1 - 0.004 16.9 0.0 0.011 15.5 0.0 1.6 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein DUF3970 PF13113.6 KZN90215.1 - 0.017 15.3 0.2 0.043 14.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3970) Aldedh PF00171.22 KZN90216.1 - 1.1e-144 482.4 0.0 1.4e-144 482.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KZN90216.1 - 2.9e-05 23.3 0.0 4.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 KZN90216.1 - 0.00072 19.1 0.0 0.025 14.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) DUF2417 PF10329.9 KZN90217.1 - 2.3e-83 279.2 0.0 3.1e-83 278.8 0.0 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) DUF2070 PF09843.9 KZN90217.1 - 0.19 10.0 9.0 0.27 9.5 9.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) NPL4 PF05021.15 KZN90218.1 - 3.6e-134 446.9 0.0 4.5e-134 446.6 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 KZN90218.1 - 1.8e-68 229.2 0.1 2.9e-68 228.6 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 KZN90218.1 - 3.9e-05 24.1 0.1 0.00092 19.7 0.0 2.9 2 1 0 2 2 2 1 Nuclear pore localisation protein NPL4 FMN_red PF03358.15 KZN90219.1 - 1.1e-07 31.7 0.0 1.5e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KZN90219.1 - 6.8e-07 29.2 0.0 8.6e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KZN90219.1 - 0.00059 20.1 0.2 0.0078 16.4 0.2 2.3 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 KZN90219.1 - 0.011 16.0 0.0 0.03 14.5 0.0 1.7 1 1 0 1 1 1 0 Flavodoxin domain zf-CCCH PF00642.24 KZN90220.1 - 5.9e-20 70.7 29.8 2.9e-06 27.0 1.0 5.2 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KZN90220.1 - 1.3e-14 53.7 32.0 0.00013 21.9 2.5 5.2 5 0 0 5 5 5 4 Zinc finger domain Torus PF16131.5 KZN90220.1 - 1.1e-12 48.6 25.9 9.5e-06 26.3 0.8 5.3 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 KZN90220.1 - 2.3e-05 24.0 0.8 2.3e-05 24.0 0.8 4.7 5 0 0 5 5 5 1 CCCH-type zinc finger zf-C3H1 PF10650.9 KZN90220.1 - 0.0069 16.1 6.0 0.65 9.8 0.1 3.8 4 0 0 4 4 4 2 Putative zinc-finger domain zf-CCCH_3 PF15663.5 KZN90220.1 - 0.8 9.9 14.8 2.5 8.3 2.5 4.0 2 1 2 4 4 4 0 Zinc-finger containing family Nab2p_Zf1 PF18260.1 KZN90220.1 - 6.1 6.9 16.5 2.1 8.3 4.6 3.3 3 0 0 3 3 3 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 Epimerase PF01370.21 KZN90221.1 - 1.7e-16 60.4 0.1 3.2e-16 59.5 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KZN90221.1 - 7.8e-12 44.8 0.0 2.2e-11 43.3 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KZN90221.1 - 2.5e-09 37.3 0.0 6.1e-09 36.0 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KZN90221.1 - 1.8e-08 34.2 0.2 3.9e-07 29.8 0.0 2.6 2 1 0 3 3 3 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KZN90221.1 - 2.2e-07 30.7 0.0 0.00026 20.6 0.1 2.2 2 0 0 2 2 2 2 NmrA-like family NAD_binding_4 PF07993.12 KZN90221.1 - 4e-05 22.9 0.0 0.03 13.5 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.25 KZN90221.1 - 8.2e-05 22.1 0.4 0.00068 19.1 0.0 2.3 3 0 0 3 3 3 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KZN90221.1 - 0.00015 21.0 0.0 0.00025 20.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Tautomerase_3 PF14832.6 KZN90222.1 - 1.1e-51 174.7 0.0 1.2e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.21 KZN90222.1 - 0.043 13.7 0.0 0.3 11.1 0.0 2.1 2 0 0 2 2 2 0 Tautomerase enzyme Goodbye PF17109.5 KZN90223.1 - 2.2e-37 128.2 0.0 7.1e-37 126.5 0.0 1.9 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain NACHT PF05729.12 KZN90223.1 - 1.3e-07 31.6 0.0 3.9e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KZN90223.1 - 1.9e-05 25.1 0.0 0.00013 22.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain TPR_12 PF13424.6 KZN90223.1 - 0.0003 21.0 1.2 0.0018 18.5 1.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KZN90223.1 - 0.0016 18.4 0.7 2.4 8.5 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat AAA_22 PF13401.6 KZN90223.1 - 0.0042 17.4 0.0 0.014 15.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KZN90223.1 - 0.037 14.4 0.0 0.088 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 KZN90223.1 - 0.14 12.1 0.0 4.9 7.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) TPR_16 PF13432.6 KZN90223.1 - 1.7 9.4 4.3 6.9 7.4 0.6 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_18 PF00704.28 KZN90224.1 - 5.2e-74 249.8 0.0 5.9e-74 249.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3142 PF11340.8 KZN90224.1 - 0.0058 16.5 0.0 0.008 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) Acyl-CoA_dh_1 PF00441.24 KZN90225.1 - 1.5e-16 60.9 0.1 5.1e-16 59.2 0.1 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AidB_N PF18158.1 KZN90225.1 - 3.2e-13 49.9 0.0 4.7e-11 42.9 0.0 2.4 1 1 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_M PF02770.19 KZN90225.1 - 1.2e-10 41.5 0.0 3.9e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KZN90225.1 - 0.12 12.6 1.0 0.27 11.5 0.1 2.1 2 1 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Zn_clus PF00172.18 KZN90227.1 - 2.8e-09 36.9 13.1 5.3e-09 36.0 13.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN90227.1 - 3.9e-08 32.7 0.0 6.5e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ECH_1 PF00378.20 KZN90228.1 - 2.8e-38 131.7 0.0 4.2e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KZN90228.1 - 2e-18 67.0 0.0 4e-18 66.0 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KZN90228.1 - 0.11 12.4 0.0 1 9.3 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 PIG-F PF06699.11 KZN90229.1 - 5.9e-67 225.3 3.2 7e-67 225.1 3.2 1.0 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F UPF0767 PF15990.5 KZN90229.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 UPF0767 family Rick_17kDa_Anti PF05433.15 KZN90229.1 - 0.31 11.0 4.0 5.2 7.0 0.0 2.6 2 0 0 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 KZN90229.1 - 0.57 10.2 4.8 19 5.4 0.1 2.4 2 0 0 2 2 2 0 Glycine zipper Gly-zipper_YMGG PF13441.6 KZN90229.1 - 1.1 9.0 5.3 0.44 10.3 1.4 2.2 2 1 0 2 2 2 0 YMGG-like Gly-zipper RhoGAP PF00620.27 KZN90230.1 - 5e-37 127.1 0.0 8.5e-37 126.3 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain zf-Tim10_DDP PF02953.15 KZN90231.1 - 6.2e-18 64.2 8.0 8.9e-18 63.7 8.0 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 KZN90231.1 - 0.0019 17.9 5.3 0.11 12.2 0.7 2.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) PALP PF00291.25 KZN90232.1 - 3.8e-41 141.4 0.1 4.8e-41 141.1 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NAD_binding_5 PF07994.12 KZN90233.1 - 2.9e-144 480.4 0.0 3.5e-144 480.1 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KZN90233.1 - 1.4e-45 154.0 0.7 3.2e-45 152.8 0.7 1.7 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Sugar_tr PF00083.24 KZN90234.1 - 2.2e-84 283.9 24.5 2.4e-84 283.8 24.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN90234.1 - 4.2e-20 72.0 35.1 4.2e-20 72.0 35.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KZN90235.1 - 2.8e-10 39.6 0.1 5.1e-10 38.7 0.0 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain LIM PF00412.22 KZN90236.1 - 6.1e-16 58.4 23.4 1.3e-10 41.4 4.1 3.0 3 0 0 3 3 3 2 LIM domain Terminase_GpA PF05876.12 KZN90236.1 - 0.0052 15.4 0.8 0.008 14.8 0.8 1.2 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) Cytochrome_C7 PF14522.6 KZN90236.1 - 8.4 6.5 16.1 5.5 7.1 6.5 2.5 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c GDPD PF03009.17 KZN90237.1 - 2.5e-31 109.4 0.0 5.6e-31 108.2 0.0 1.5 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family ADH_zinc_N PF00107.26 KZN90239.1 - 5e-27 94.4 0.1 7.3e-27 93.9 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KZN90239.1 - 9.1e-22 78.5 0.0 1.6e-21 77.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KZN90239.1 - 3.6e-10 39.7 0.3 9.8e-10 38.3 0.3 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Cupin_2 PF07883.11 KZN90240.1 - 3e-07 30.0 0.0 6.6e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KZN90240.1 - 0.019 14.6 0.0 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) UBA_5 PF16577.5 KZN90240.1 - 0.12 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 UBA domain Sulfotransfer_4 PF17784.1 KZN90241.1 - 4.6e-50 170.4 0.0 5.5e-50 170.2 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_1 PF00685.27 KZN90241.1 - 0.13 11.7 0.0 0.31 10.5 0.0 1.8 1 1 0 1 1 1 0 Sulfotransferase domain MFS_1 PF07690.16 KZN90242.1 - 1.2e-33 116.5 27.0 1.2e-33 116.5 27.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Oleosin PF01277.17 KZN90242.1 - 2.4 8.0 5.6 5.9 6.7 0.0 3.5 3 0 0 3 3 3 0 Oleosin Lipase_GDSL_2 PF13472.6 KZN90243.1 - 2.4e-19 70.4 0.3 3.7e-19 69.8 0.3 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KZN90243.1 - 8.2e-10 39.0 0.0 1.4e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase NUP PF06516.11 KZN90244.1 - 3e-135 450.4 0.2 3.5e-135 450.2 0.2 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Ank_2 PF12796.7 KZN90245.1 - 5.5e-113 369.8 30.6 1.6e-12 47.8 0.1 14.8 5 4 5 14 14 14 14 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN90245.1 - 4.1e-95 311.0 27.2 2.1e-07 31.3 0.0 23.7 10 6 16 26 26 26 21 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN90245.1 - 1.2e-76 243.5 41.9 0.012 16.1 0.0 31.0 31 0 0 31 31 31 23 Ankyrin repeat Ank_5 PF13857.6 KZN90245.1 - 7.8e-60 198.2 44.8 4.8e-05 23.6 0.0 20.6 10 5 13 23 23 23 17 Ankyrin repeats (many copies) Ank PF00023.30 KZN90245.1 - 1.4e-53 177.1 70.8 0.0022 18.4 0.0 31.0 33 0 0 33 33 33 16 Ankyrin repeat Goodbye PF17109.5 KZN90245.1 - 8.8e-06 26.2 0.0 4.6e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain NACHT PF05729.12 KZN90245.1 - 3.5e-05 23.8 0.1 0.00011 22.2 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KZN90245.1 - 4.9e-05 23.6 0.0 0.00016 22.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain NAPRTase_N PF17767.1 KZN90245.1 - 0.044 14.2 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain DUF4440 PF14534.6 KZN90246.1 - 5.8e-10 39.5 0.0 6.6e-10 39.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 KZN90246.1 - 0.067 13.8 0.0 0.083 13.5 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain MFS_1 PF07690.16 KZN90247.1 - 1.6e-38 132.5 34.3 1.5e-33 116.2 26.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KZN90247.1 - 0.0019 16.6 5.9 0.0027 16.0 0.3 2.9 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF2955 PF11168.8 KZN90247.1 - 0.0027 17.6 4.0 0.0027 17.6 4.0 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF2955) LacY_symp PF01306.19 KZN90247.1 - 4.9 5.8 15.4 3.7 6.2 0.1 3.0 3 1 0 3 3 3 0 LacY proton/sugar symporter FAD_binding_3 PF01494.19 KZN90248.1 - 1e-13 51.3 0.1 9.5e-13 48.1 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KZN90248.1 - 1.2e-06 28.4 1.3 3.5e-05 23.6 0.1 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KZN90248.1 - 1.1e-05 25.6 0.1 2.5e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KZN90248.1 - 3e-05 23.4 1.0 0.0017 17.6 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KZN90248.1 - 0.0021 18.1 0.4 0.027 14.5 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KZN90248.1 - 0.0091 15.3 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 KZN90248.1 - 0.018 13.9 2.5 0.27 10.0 0.1 2.5 3 0 0 3 3 3 0 Tryptophan halogenase FAD_binding_2 PF00890.24 KZN90248.1 - 0.25 10.4 3.4 0.69 8.9 3.5 1.7 2 1 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 KZN90248.1 - 0.64 9.2 1.6 1.6 7.9 0.7 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pec_lyase_C PF00544.19 KZN90249.1 - 6.9e-43 146.7 11.0 1e-42 146.1 11.0 1.2 1 0 0 1 1 1 1 Pectate lyase DIOX_N PF14226.6 KZN90250.1 - 4.4e-27 95.2 0.0 8.1e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KZN90250.1 - 1.3e-17 64.2 0.0 2.6e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAD_binding_4 PF01565.23 KZN90251.1 - 5.8e-31 107.1 7.7 9.2e-31 106.4 7.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KZN90251.1 - 1.2e-12 47.7 0.2 2.3e-12 46.8 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like ALO PF04030.14 KZN90251.1 - 0.039 13.8 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase Aldedh PF00171.22 KZN90252.1 - 9.3e-138 459.6 0.4 1e-137 459.4 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KZN90252.1 - 0.0017 17.5 0.0 0.0023 17.1 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1275 PF06912.11 KZN90253.1 - 3.2e-47 161.0 11.2 3.7e-47 160.7 11.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Pcc1 PF09341.10 KZN90254.1 - 1.4e-32 111.6 0.4 1.8e-32 111.3 0.4 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 PEP_mutase PF13714.6 KZN90255.1 - 3e-41 141.4 0.0 3.6e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KZN90255.1 - 8.1e-22 77.4 0.0 1.1e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 Isocitrate lyase family MIEAP PF16026.5 KZN90256.1 - 0.0043 17.3 0.2 0.0092 16.2 0.2 1.5 1 0 0 1 1 1 1 Mitochondria-eating protein Apt1 PF10351.9 KZN90256.1 - 0.0067 15.3 1.8 0.011 14.7 1.8 1.2 1 0 0 1 1 1 1 Golgi-body localisation protein domain GIT_CC PF16559.5 KZN90256.1 - 0.01 15.7 0.2 0.15 11.9 0.0 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor CCDC92 PF14916.6 KZN90256.1 - 0.065 13.0 0.7 0.28 11.0 0.7 2.1 1 1 0 1 1 1 0 Coiled-coil domain of unknown function GAS PF13851.6 KZN90256.1 - 0.086 12.2 4.5 0.2 11.0 4.5 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 KZN90256.1 - 0.12 12.6 7.2 0.34 11.1 5.4 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 OrfB_IS605 PF01385.19 KZN90256.1 - 0.72 10.1 3.4 2 8.7 0.8 2.5 2 1 1 3 3 3 0 Probable transposase HSP70 PF00012.20 KZN90257.1 - 0.00021 19.7 0.1 0.0021 16.3 0.0 2.3 2 1 0 2 2 2 2 Hsp70 protein Glyco_hydro_20 PF00728.22 KZN90258.1 - 1.7e-23 83.6 0.5 7e-17 61.9 0.0 2.6 1 1 1 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 KZN90258.1 - 6.7e-09 36.6 0.0 1.9e-08 35.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Fungal_trans PF04082.18 KZN90259.1 - 6.5e-16 58.1 0.3 1.5e-15 57.0 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN90259.1 - 9.1e-06 25.7 9.6 1.8e-05 24.8 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2655 PF10848.8 KZN90259.1 - 0.039 14.3 0.0 0.082 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2655) AMP-binding PF00501.28 KZN90261.1 - 8.6e-84 281.6 0.0 1.1e-83 281.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KZN90261.1 - 7.5e-13 49.3 0.0 2.6e-12 47.5 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF1275 PF06912.11 KZN90262.1 - 1e-42 146.3 11.6 1.3e-42 145.9 11.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF4603 PF15376.6 KZN90262.1 - 0.11 9.9 0.1 0.14 9.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) ECF_trnsprt PF12822.7 KZN90262.1 - 0.17 12.0 11.4 0.058 13.5 3.3 2.2 1 1 0 2 2 2 0 ECF transporter, substrate-specific component PHO4 PF01384.20 KZN90262.1 - 0.35 9.8 7.1 0.89 8.5 6.9 1.6 1 1 0 1 1 1 0 Phosphate transporter family FA_desaturase PF00487.24 KZN90263.1 - 1.1e-29 104.0 26.0 2.4e-29 102.9 26.0 1.5 1 1 0 1 1 1 1 Fatty acid desaturase PTR2 PF00854.21 KZN90264.1 - 1.3e-51 175.7 6.4 1.9e-51 175.2 6.4 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 KZN90264.1 - 5e-10 38.8 23.3 2.6e-09 36.5 23.9 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_3_6 PF07332.11 KZN90264.1 - 0.059 13.4 13.3 0.48 10.5 0.1 3.9 4 0 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III Acetyltransf_3 PF13302.7 KZN90265.1 - 2.2e-15 57.5 0.0 4.7e-15 56.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KZN90265.1 - 1.9e-08 34.5 0.0 3.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KZN90265.1 - 0.0012 18.5 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KZN90265.1 - 0.0078 16.2 0.0 0.023 14.6 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.7 KZN90265.1 - 0.041 14.0 0.0 0.07 13.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1581 PF07619.11 KZN90265.1 - 0.072 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1581) FMO-like PF00743.19 KZN90266.1 - 8.1e-28 97.1 0.0 6.4e-10 38.1 0.0 3.1 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KZN90266.1 - 1e-13 51.3 0.1 1.6e-08 34.2 0.1 3.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KZN90266.1 - 2.1e-09 37.0 0.0 1.1e-08 34.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KZN90266.1 - 5.2e-08 33.0 0.0 0.0012 18.9 0.0 3.1 3 0 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 KZN90266.1 - 9.3e-07 28.3 0.1 0.0026 17.0 0.0 3.2 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KZN90266.1 - 1.7e-06 28.1 0.0 5.4e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KZN90266.1 - 4.7e-05 23.1 0.1 0.5 9.9 0.0 2.9 2 1 1 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 KZN90266.1 - 0.0014 17.9 0.1 0.017 14.4 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KZN90266.1 - 0.0024 18.4 0.4 1.8 9.2 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KZN90266.1 - 0.14 11.5 0.0 0.33 10.3 0.0 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase His_Phos_1 PF00300.22 KZN90267.1 - 0.0029 17.3 0.0 0.0045 16.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Sugar_tr PF00083.24 KZN90268.1 - 1e-110 370.7 17.5 1.4e-110 370.3 17.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN90268.1 - 1.9e-21 76.4 24.3 1.9e-21 76.4 24.3 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM151 PF14857.6 KZN90268.1 - 0.045 12.7 0.0 0.07 12.0 0.0 1.2 1 0 0 1 1 1 0 TMEM151 family F-box-like PF12937.7 KZN90270.1 - 0.00011 22.0 0.1 0.00026 20.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like Redoxin PF08534.10 KZN90271.1 - 1.7e-36 125.2 0.0 1.9e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KZN90271.1 - 3.6e-12 46.3 0.0 4.6e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family AP_endonuc_2 PF01261.24 KZN90272.1 - 8.5e-12 45.0 0.0 1.3e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Zn_clus PF00172.18 KZN90273.1 - 0.32 11.2 3.2 0.53 10.5 3.2 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_2 PF00890.24 KZN90274.1 - 1.9e-37 129.4 1.3 4.8e-36 124.7 1.3 2.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KZN90274.1 - 1.2e-10 41.5 0.1 1.9e-09 37.6 0.1 2.4 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KZN90274.1 - 9.4e-10 38.4 0.1 1.4e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KZN90274.1 - 2.4e-08 34.1 0.1 8.7e-08 32.3 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KZN90274.1 - 2.3e-06 27.1 0.5 2.1e-05 23.9 0.7 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KZN90274.1 - 4.8e-06 26.0 0.0 1.1e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KZN90274.1 - 9.1e-06 24.6 0.9 2.3e-05 23.3 0.9 1.9 1 1 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KZN90274.1 - 0.0031 16.8 0.8 0.0053 16.1 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KZN90274.1 - 0.004 17.7 1.0 0.0087 16.6 0.4 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KZN90274.1 - 0.0046 16.3 0.5 0.0086 15.4 0.5 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KZN90274.1 - 0.0056 16.0 1.8 0.022 14.0 0.4 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KZN90274.1 - 0.0073 15.4 2.9 0.0073 15.4 2.9 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_7 PF13241.6 KZN90274.1 - 0.13 12.7 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding ADH_N PF08240.12 KZN90275.1 - 1.5e-21 76.3 1.5 2.6e-21 75.5 1.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN90275.1 - 6.6e-16 58.5 0.0 1.1e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KZN90275.1 - 8.5e-05 22.0 0.2 0.00014 21.3 0.2 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KZN90275.1 - 0.00013 21.4 0.2 0.0002 20.7 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 KZN90275.1 - 0.029 13.7 0.2 0.043 13.2 0.2 1.2 1 0 0 1 1 1 0 ThiF family 3HCDH_N PF02737.18 KZN90275.1 - 0.03 14.2 0.1 0.046 13.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KZN90275.1 - 0.048 13.8 0.1 0.084 13.0 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.25 KZN90275.1 - 0.15 11.5 0.6 17 4.8 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase DUF1075 PF06388.11 KZN90276.1 - 0.062 13.3 0.4 0.18 11.8 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1075) SPC25 PF06703.11 KZN90276.1 - 0.3 10.9 0.9 1.4 8.6 0.1 2.1 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Pyr_redox_3 PF13738.6 KZN90277.1 - 3.3e-13 49.6 0.0 6.6e-13 48.6 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KZN90277.1 - 4.9e-12 45.1 0.0 3.5e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KZN90277.1 - 1.4e-11 44.2 0.0 3.5e-11 42.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KZN90277.1 - 5.8e-07 29.0 0.0 1.9e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KZN90277.1 - 8.5e-07 29.1 0.1 2.6e-06 27.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KZN90277.1 - 6.6e-05 22.3 0.2 0.00018 20.9 0.1 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 KZN90277.1 - 0.0016 18.4 1.0 0.024 14.7 0.2 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KZN90277.1 - 0.0054 15.8 0.0 0.0087 15.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 KZN90277.1 - 0.0066 15.2 0.1 0.57 8.8 0.1 2.5 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.7 KZN90277.1 - 0.1 11.9 0.0 0.74 9.1 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KZN90277.1 - 0.13 11.4 0.1 0.23 10.5 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain DUF4769 PF15992.5 KZN90277.1 - 0.24 11.2 0.0 0.37 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4769) zf-C2H2 PF00096.26 KZN90279.1 - 8.7e-12 44.8 11.0 7e-06 26.2 0.7 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KZN90279.1 - 2.4e-09 37.2 9.2 0.00021 21.9 0.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KZN90279.1 - 3e-08 33.7 9.4 4.9e-06 26.7 2.2 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 KZN90279.1 - 4.8e-05 23.0 7.8 0.0069 16.1 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KZN90279.1 - 0.0021 18.3 7.1 0.0067 16.7 0.1 2.6 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KZN90279.1 - 0.0022 18.0 5.5 0.37 10.9 0.5 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HE PF16278.5 KZN90279.1 - 0.068 13.6 7.7 1.8 9.1 1.4 2.2 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 KZN90279.1 - 0.3 11.5 0.2 0.3 11.5 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KZN90279.1 - 0.43 10.4 3.6 5.3 6.9 0.3 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-CHY PF05495.12 KZN90279.1 - 0.89 10.1 3.5 3.1 8.4 3.7 1.7 1 1 0 1 1 1 0 CHY zinc finger zf-AN1 PF01428.16 KZN90279.1 - 4.7 7.5 8.2 18 5.6 1.8 2.3 1 1 1 2 2 2 0 AN1-like Zinc finger DLH PF01738.18 KZN90280.1 - 1.4e-15 57.5 0.0 1.8e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Zn_clus PF00172.18 KZN90282.1 - 3.6e-08 33.4 6.3 5.3e-08 32.9 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MGC-24 PF05283.11 KZN90282.1 - 0.25 11.8 1.6 0.59 10.6 1.6 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GATA PF00320.27 KZN90283.1 - 1.7e-16 59.5 2.3 3.2e-16 58.6 2.3 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 KZN90283.1 - 7.9e-13 48.0 2.4 1.6e-12 47.0 2.4 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) AreA_N PF07573.11 KZN90283.1 - 3.6e-10 40.3 5.5 3.6e-10 40.3 5.5 4.6 3 2 1 4 4 4 1 Nitrogen regulatory protein AreA N terminus HSP9_HSP12 PF04119.12 KZN90284.1 - 0.011 16.1 0.6 0.37 11.2 0.3 2.6 2 1 0 2 2 2 0 Heat shock protein 9/12 Ipi1_N PF12333.8 KZN90285.1 - 3.7e-28 98.1 0.7 2e-27 95.8 0.0 2.3 2 1 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation HEAT_EZ PF13513.6 KZN90285.1 - 0.14 12.7 1.2 19 5.9 0.3 2.5 1 1 1 2 2 2 0 HEAT-like repeat HEAT PF02985.22 KZN90285.1 - 1.2 9.6 2.9 23 5.6 0.1 3.3 4 0 0 4 4 4 0 HEAT repeat bZIP_2 PF07716.15 KZN90286.1 - 0.39 10.8 2.5 0.33 11.1 0.2 2.0 2 0 0 2 2 2 0 Basic region leucine zipper Robl_LC7 PF03259.17 KZN90287.1 - 1.2e-07 31.3 0.2 0.013 15.3 0.0 3.1 3 0 0 3 3 3 3 Roadblock/LC7 domain DUF4988 PF16378.5 KZN90287.1 - 0.083 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function Aminotran_5 PF00266.19 KZN90288.1 - 6.6e-55 186.6 0.0 9.2e-55 186.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KZN90288.1 - 0.00026 19.6 0.0 0.00042 19.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KZN90288.1 - 0.00072 18.8 0.1 0.0011 18.2 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cyclin PF08613.11 KZN90289.1 - 1.4e-05 25.5 0.0 1.4e-05 25.5 0.0 2.5 3 0 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 KZN90289.1 - 0.011 15.5 0.1 0.023 14.5 0.1 1.6 1 1 0 1 1 1 0 Cyclin, N-terminal domain DUF3399 PF11879.8 KZN90289.1 - 0.86 10.0 0.0 0.86 10.0 0.0 5.0 6 0 0 6 6 6 0 Domain of unknown function (DUF3399) Transp_cyt_pur PF02133.15 KZN90290.1 - 2.1e-87 293.7 40.8 2.5e-87 293.5 40.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pyrid_oxidase_2 PF13883.6 KZN90291.1 - 2.3e-32 112.3 0.0 3.3e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase SEN1_N PF12726.7 KZN90292.1 - 1.5e-205 684.7 1.9 2.2e-205 684.2 1.9 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 KZN90292.1 - 1.8e-75 254.1 1.8 1.8e-75 254.1 1.8 2.4 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KZN90292.1 - 3.9e-61 206.1 0.0 7.3e-61 205.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KZN90292.1 - 6.6e-10 39.0 0.3 9e-06 25.5 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KZN90292.1 - 1e-08 35.7 0.0 3.1e-08 34.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KZN90292.1 - 2.4e-07 30.7 0.2 0.026 14.3 0.1 3.5 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KZN90292.1 - 3e-06 27.0 0.2 0.00032 20.3 0.2 2.5 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain T2SSE PF00437.20 KZN90292.1 - 0.0043 16.2 0.0 0.01 14.9 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.9 KZN90292.1 - 0.0069 15.7 0.3 0.29 10.3 0.0 2.7 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 KZN90292.1 - 0.03 14.8 0.0 0.08 13.4 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 KZN90292.1 - 0.07 13.1 0.8 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KZN90292.1 - 0.079 13.3 0.0 0.25 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 KZN90292.1 - 0.082 12.6 0.0 0.31 10.7 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain DEAD PF00270.29 KZN90292.1 - 0.084 12.6 0.3 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF4164 PF13747.6 KZN90292.1 - 0.11 12.8 3.8 0.52 10.6 3.8 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) TPR_MLP1_2 PF07926.12 KZN90292.1 - 0.48 10.5 5.7 0.046 13.8 0.4 2.1 2 0 0 2 2 1 0 TPR/MLP1/MLP2-like protein zf-CCHC_3 PF13917.6 KZN90292.1 - 1.2 9.1 17.5 0.19 11.7 0.3 3.8 1 1 2 3 3 3 0 Zinc knuckle PhoLip_ATPase_C PF16212.5 KZN90293.1 - 4.1e-80 269.1 25.4 4.1e-80 269.1 25.4 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KZN90293.1 - 2.6e-19 68.6 1.2 7.6e-19 67.2 1.2 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KZN90293.1 - 5.4e-12 45.6 0.0 2.3e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KZN90293.1 - 2e-09 38.1 4.6 1.5e-05 25.4 1.2 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KZN90293.1 - 0.0023 17.5 0.3 0.027 14.0 0.0 2.6 2 2 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KZN90293.1 - 0.042 13.6 0.4 0.11 12.2 0.4 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase vATP-synt_E PF01991.18 KZN90295.1 - 3.8e-62 209.2 9.2 4.4e-62 209.0 9.2 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Med3 PF11593.8 KZN90295.1 - 0.085 12.0 0.9 0.098 11.8 0.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4288 PF14119.6 KZN90295.1 - 0.75 10.2 7.9 14 6.1 0.6 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4288) DUF4473 PF14747.6 KZN90295.1 - 2.2 8.9 8.6 8.3 7.0 2.5 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4473) Mg_trans_NIPA PF05653.14 KZN90296.1 - 1.1e-14 54.3 7.8 4.7e-10 39.1 1.8 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KZN90296.1 - 1e-05 25.7 0.7 1e-05 25.7 0.7 2.8 3 0 0 3 3 3 1 EamA-like transporter family PUNUT PF16913.5 KZN90296.1 - 2e-05 24.0 0.1 2e-05 24.0 0.1 2.0 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport SRF-TF PF00319.18 KZN90297.1 - 3.2e-21 74.5 0.1 4.7e-21 74.0 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF604 PF04646.12 KZN90298.1 - 1e-07 31.6 0.0 1.6e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 KZN90298.1 - 0.0003 20.3 0.0 0.00064 19.2 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Ser_hydrolase PF06821.13 KZN90298.1 - 0.07 13.0 0.2 0.15 11.9 0.2 1.5 1 0 0 1 1 1 0 Serine hydrolase DUF4106 PF13388.6 KZN90298.1 - 1.2 8.3 3.0 0.91 8.7 1.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4106) Lactamase_B_2 PF12706.7 KZN90299.1 - 6.8e-11 42.1 0.1 1e-10 41.5 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KZN90299.1 - 1.9e-08 34.4 0.0 2.6e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Isochorismatase PF00857.20 KZN90300.1 - 8.4e-40 136.8 0.1 9.5e-40 136.6 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family SPATA9 PF15824.5 KZN90300.1 - 0.17 11.2 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 9 SLAC1 PF03595.17 KZN90301.1 - 1.4e-94 317.0 54.9 1.6e-94 316.9 54.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel TPR_2 PF07719.17 KZN90302.1 - 1.8e-09 37.0 16.3 0.062 13.4 0.0 7.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 KZN90302.1 - 0.00096 18.8 2.1 4.4 7.1 0.0 5.1 5 0 0 5 5 5 1 TPR repeat TPR_4 PF07721.14 KZN90302.1 - 0.0038 17.7 10.2 3.6 8.5 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KZN90302.1 - 0.0042 17.7 22.5 0.24 12.1 0.1 6.6 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KZN90302.1 - 0.0053 17.0 5.2 1.3 9.6 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KZN90302.1 - 0.0058 16.4 10.4 7.4 6.6 0.0 6.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KZN90302.1 - 0.0075 16.4 11.3 9.4 6.7 0.2 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 KZN90302.1 - 0.48 10.7 11.9 1.8 8.9 0.7 5.0 4 2 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KZN90302.1 - 2.6 8.9 7.7 39 5.2 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KZN90302.1 - 3.5 7.6 5.0 44 4.1 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Fungal_trans PF04082.18 KZN90303.1 - 4.3e-08 32.5 0.4 1e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Sulfatase PF00884.23 KZN90304.1 - 4.3e-60 203.7 3.0 5.6e-60 203.3 3.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KZN90304.1 - 9e-05 22.2 3.4 0.0007 19.3 3.4 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KZN90304.1 - 0.043 14.1 0.1 0.095 13.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) DUF229 PF02995.17 KZN90304.1 - 0.14 10.7 1.0 0.26 9.8 0.1 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF229) DUF3285 PF11688.8 KZN90304.1 - 0.18 11.7 0.1 0.33 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3285) Glyco_hydro_3_C PF01915.22 KZN90305.1 - 4.4e-54 183.6 0.0 6e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KZN90305.1 - 3.8e-46 157.9 0.0 5.8e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KZN90305.1 - 8.2e-17 61.1 0.1 2.1e-16 59.8 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KZN90305.1 - 1.6e-11 44.2 0.0 2.7e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Sugar_tr PF00083.24 KZN90306.1 - 4.8e-86 289.4 23.8 5.6e-86 289.2 23.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN90306.1 - 8.9e-16 57.7 54.3 8e-15 54.6 26.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KZN90307.1 - 4.3e-26 91.7 45.7 4.3e-26 91.7 45.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_1 PF00561.20 KZN90308.1 - 2.9e-21 76.3 0.0 4.2e-18 65.9 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KZN90308.1 - 3e-15 57.4 0.0 3.9e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KZN90308.1 - 1.5e-14 53.9 0.1 2.4e-13 49.9 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KZN90308.1 - 0.00087 19.2 0.0 0.0019 18.1 0.0 1.6 2 0 0 2 2 2 1 Serine hydrolase Ndr PF03096.14 KZN90308.1 - 0.0029 16.3 0.0 0.051 12.3 0.0 2.0 2 0 0 2 2 2 1 Ndr family Abhydrolase_5 PF12695.7 KZN90308.1 - 0.018 14.8 0.0 0.064 13.0 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Transferase PF02458.15 KZN90309.1 - 0.16 10.6 0.0 2 7.0 0.0 2.0 2 0 0 2 2 2 0 Transferase family SQHop_cyclase_N PF13249.6 KZN90310.1 - 1.7e-115 385.1 0.4 2.2e-105 352.0 0.0 4.6 3 2 2 5 5 5 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KZN90310.1 - 2.4e-115 385.1 2.2 9.6e-109 363.3 0.8 3.1 3 0 0 3 3 3 3 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 KZN90310.1 - 3.9e-30 103.3 18.2 4.2e-09 36.0 0.1 7.6 8 0 0 8 8 8 5 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 KZN90310.1 - 1.2e-05 24.5 0.0 1.1 8.2 0.0 4.8 4 1 0 5 5 5 2 A-macroglobulin TED domain Pec_lyase PF09492.10 KZN90310.1 - 0.008 15.5 0.5 45 3.2 0.0 4.6 6 0 0 6 6 6 0 Pectic acid lyase p450 PF00067.22 KZN90311.1 - 6.5e-40 137.2 0.0 1.5e-39 136.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 SNN_linker PF09050.10 KZN90312.1 - 0.059 13.2 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Stannin unstructured linker MFS_1 PF07690.16 KZN90313.1 - 2e-33 115.8 27.2 3.3e-33 115.1 26.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily LapA_dom PF06305.11 KZN90313.1 - 1.2 9.0 0.0 1.2 9.0 0.0 4.3 5 1 1 6 6 6 0 Lipopolysaccharide assembly protein A domain Phage_holin_2_1 PF04971.12 KZN90313.1 - 1.6 8.8 10.0 0.53 10.3 0.1 3.3 2 1 1 3 3 3 0 Bacteriophage P21 holin S WD40 PF00400.32 KZN90314.1 - 4.1e-61 201.5 17.7 1.5e-11 44.6 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN90314.1 - 8.3e-28 96.5 0.2 4.6e-05 23.6 0.0 6.0 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KZN90314.1 - 1.5e-11 43.8 0.4 0.02 13.8 0.0 5.6 1 1 5 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KZN90314.1 - 3.1e-07 30.2 0.8 0.35 10.9 0.0 5.1 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 KZN90314.1 - 0.00025 20.7 0.8 16 5.3 0.0 4.5 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Gmad1 PF10647.9 KZN90314.1 - 0.00028 20.7 0.4 0.043 13.6 0.1 2.6 1 1 1 2 2 2 2 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 KZN90314.1 - 0.00046 19.0 8.4 1.1 7.9 0.0 4.4 2 1 2 5 5 5 3 Nucleoporin Nup120/160 Ret2_MD PF18528.1 KZN90314.1 - 0.0025 18.1 0.0 2.9 8.3 0.0 4.0 2 1 2 4 4 4 1 RNA editing 3' terminal uridylyl transferase 2 middle domain TruB_C PF09142.11 KZN90314.1 - 0.0066 16.2 0.0 9 6.2 0.0 4.1 5 0 0 5 5 5 1 tRNA Pseudouridine synthase II, C terminal DUF5570 PF17731.1 KZN90314.1 - 0.0079 16.3 5.6 0.38 10.9 0.2 4.1 2 1 3 5 5 5 1 Family of unknown function (DUF5570) Nucleoporin_N PF08801.11 KZN90314.1 - 0.019 13.7 0.4 0.78 8.4 0.1 2.9 1 1 1 3 3 3 0 Nup133 N terminal like DUF5046 PF16465.5 KZN90314.1 - 0.049 13.1 0.1 15 4.9 0.0 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF5046) MBD PF01429.19 KZN90314.1 - 0.073 12.8 0.0 6.5 6.5 0.0 3.4 2 1 1 3 3 3 0 Methyl-CpG binding domain FMN_dh PF01070.18 KZN90315.1 - 1.3e-120 402.6 0.0 1.4e-120 402.5 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 KZN90315.1 - 2.4e-05 23.8 0.0 0.033 13.5 0.2 2.9 2 1 0 3 3 3 2 Thiazole biosynthesis protein ThiG NMO PF03060.15 KZN90315.1 - 3.3e-05 23.5 0.3 5e-05 22.8 0.3 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KZN90315.1 - 0.00091 18.3 0.1 0.002 17.2 0.1 1.6 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KZN90315.1 - 0.001 18.3 0.1 0.0016 17.7 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KZN90315.1 - 0.026 14.0 0.1 0.55 9.6 0.1 2.6 1 1 1 2 2 2 0 Histidine biosynthesis protein DHO_dh PF01180.21 KZN90315.1 - 0.21 10.7 0.2 1.2 8.3 0.2 2.0 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Lipase_3 PF01764.25 KZN90316.1 - 1.2e-15 57.6 0.0 1.3e-11 44.6 0.0 2.4 2 0 0 2 2 2 2 Lipase (class 3) Abhydrolase_6 PF12697.7 KZN90316.1 - 0.0067 17.0 1.4 0.0067 17.0 1.4 1.9 1 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KZN90316.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 zf-C2H2 PF00096.26 KZN90317.1 - 0.00015 22.0 15.6 0.0037 17.6 3.2 3.2 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KZN90317.1 - 0.00068 19.9 1.6 0.00068 19.9 1.6 3.6 3 0 0 3 3 3 1 Zinc-finger double domain Zn-ribbon_8 PF09723.10 KZN90317.1 - 0.52 10.5 2.4 12 6.1 0.4 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_4 PF13894.6 KZN90317.1 - 6.7 7.8 24.9 0.48 11.4 2.7 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.15 KZN90317.1 - 8.7 6.5 13.0 2 8.5 4.3 2.6 1 1 1 2 2 2 0 BED zinc finger SMC_N PF02463.19 KZN90318.1 - 2.1e-22 79.6 0.0 5.5e-22 78.3 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KZN90318.1 - 6e-18 66.1 0.0 6e-18 66.1 0.0 4.5 2 2 1 4 4 4 1 AAA domain AAA_15 PF13175.6 KZN90318.1 - 5.2e-05 23.1 0.1 5.2e-05 23.1 0.1 3.7 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KZN90318.1 - 0.00036 20.2 0.0 0.00069 19.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KZN90318.1 - 0.0024 17.7 8.4 0.034 14.0 0.1 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 KZN90318.1 - 0.11 13.1 0.0 0.11 13.1 0.0 4.6 3 2 0 3 3 3 0 ABC transporter tRNA-synt_2b PF00587.25 KZN90318.1 - 2 8.3 6.8 0.17 11.9 1.2 2.1 3 1 0 3 3 3 0 tRNA synthetase class II core domain (G, H, P, S and T) BTB PF00651.31 KZN90319.1 - 3.4e-25 88.4 0.0 1.3e-12 47.9 0.4 2.6 2 0 0 2 2 2 2 BTB/POZ domain Ank_5 PF13857.6 KZN90319.1 - 1.8e-07 31.3 0.2 8.1e-07 29.2 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KZN90319.1 - 7.1e-07 29.7 0.0 1.8e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KZN90319.1 - 7.3e-07 29.7 0.0 1.6e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KZN90319.1 - 9.6e-06 25.8 0.0 0.0012 19.2 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KZN90319.1 - 0.0053 17.2 0.0 0.083 13.5 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat DUF3342 PF11822.8 KZN90319.1 - 0.011 16.0 0.1 0.023 14.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) Pkinase PF00069.25 KZN90320.1 - 2.7e-53 181.0 4.6 1.9e-34 119.2 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KZN90320.1 - 3.9e-36 124.7 0.0 9.6e-26 90.6 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KZN90320.1 - 0.014 14.7 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KZN90320.1 - 0.042 13.8 0.4 0.84 9.5 0.0 2.5 2 1 0 2 2 2 0 Phosphotransferase enzyme family DUF3896 PF13035.6 KZN90320.1 - 1.1 9.4 6.6 0.5 10.6 0.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3896) Wbp11 PF09429.10 KZN90321.1 - 1.7e-20 73.2 13.2 1.7e-20 73.2 13.2 2.4 2 1 0 2 2 2 1 WW domain binding protein 11 DUF1664 PF07889.12 KZN90322.1 - 0.0012 18.8 0.9 0.0033 17.5 0.9 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.13 KZN90322.1 - 0.0041 16.7 0.3 0.0066 16.0 0.3 1.3 1 0 0 1 1 1 1 fzo-like conserved region Fib_alpha PF08702.10 KZN90322.1 - 0.01 16.0 1.6 0.026 14.7 1.6 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family PhaP_Bmeg PF09602.10 KZN90322.1 - 0.013 15.5 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Cobalamin_bind PF01122.19 KZN90322.1 - 0.037 12.9 0.0 0.051 12.5 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic cobalamin-binding protein Baculo_PEP_C PF04513.12 KZN90322.1 - 0.039 14.0 0.3 0.5 10.4 0.3 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HSCB_C PF07743.13 KZN90322.1 - 0.053 14.0 0.8 1.6 9.2 0.1 2.3 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain DUF4407 PF14362.6 KZN90322.1 - 0.067 12.5 1.5 0.074 12.4 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Rpr2 PF04032.16 KZN90323.1 - 1.5e-26 92.5 1.1 2.7e-26 91.7 1.1 1.4 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain HicB_lk_antitox PF15919.5 KZN90323.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system Nudix_N_2 PF14803.6 KZN90323.1 - 0.14 12.1 0.8 1.9 8.5 0.1 2.6 2 0 0 2 2 2 0 Nudix N-terminal DEAD PF00270.29 KZN90324.1 - 2.9e-36 124.9 0.2 6.6e-36 123.7 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KZN90324.1 - 9.1e-28 96.8 0.1 8.8e-25 87.2 0.1 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KZN90324.1 - 7.7e-09 35.8 0.0 1.9e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4844 PF16133.5 KZN90324.1 - 0.17 12.4 1.4 0.31 11.6 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4844) ApbA PF02558.16 KZN90325.1 - 5e-26 91.2 0.0 7.7e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KZN90325.1 - 3.5e-19 69.2 0.0 6.4e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DASH_Hsk3 PF08227.11 KZN90326.1 - 1.1e-21 76.9 2.4 1.5e-21 76.4 2.4 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like BBS2_C PF14782.6 KZN90326.1 - 0.11 11.2 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Cupin_1 PF00190.22 KZN90326.1 - 0.16 11.5 2.4 0.28 10.8 2.4 1.4 1 0 0 1 1 1 0 Cupin His_Phos_1 PF00300.22 KZN90327.1 - 1.4e-36 126.1 0.5 1.8e-20 73.4 0.1 2.2 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AdoMet_MTase PF07757.13 KZN90328.1 - 1.1e-26 93.4 0.0 2.2e-26 92.4 0.0 1.5 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase CorA PF01544.18 KZN90329.1 - 1.4e-07 31.1 0.0 2.6e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DDE_Tnp_ISL3 PF01610.17 KZN90329.1 - 0.029 14.1 0.1 0.048 13.4 0.1 1.3 1 0 0 1 1 1 0 Transposase ApoL PF05461.11 KZN90329.1 - 0.041 13.2 0.5 0.041 13.2 0.5 1.6 2 0 0 2 2 2 0 Apolipoprotein L WH1 PF00568.23 KZN90331.1 - 1.6e-28 98.8 0.0 2.5e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 KZN90331.1 - 0.0068 16.2 5.1 0.03 14.2 5.1 2.1 1 1 0 1 1 1 1 WH2 motif ERCC4 PF02732.15 KZN90334.1 - 4.2e-18 66.0 0.0 2.4e-17 63.6 0.0 2.3 2 0 0 2 2 2 1 ERCC4 domain HHH_5 PF14520.6 KZN90334.1 - 0.024 15.2 0.0 0.061 13.9 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain Peptidase_S41 PF03572.18 KZN90335.1 - 5.3e-09 35.8 0.0 1.3e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Peptidase family S41 DUF397 PF04149.12 KZN90335.1 - 0.054 13.6 0.0 0.87 9.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF397) eIF-1a PF01176.19 KZN90336.1 - 4.2e-22 77.7 0.0 5.9e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DUF3124 PF11322.8 KZN90336.1 - 0.071 13.3 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3124) fn3_2 PF16893.5 KZN90337.1 - 2.7e-38 130.0 0.0 5e-38 129.1 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 KZN90337.1 - 5.9e-25 87.0 0.4 1.1e-24 86.2 0.4 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 KZN90337.1 - 9.8e-13 47.8 0.0 1.7e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KZN90337.1 - 4.2e-08 33.4 0.0 7.7e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.8 KZN90337.1 - 2.4e-05 24.5 0.0 5.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3 PF00041.21 KZN90337.1 - 0.00099 19.4 0.0 0.0036 17.6 0.0 2.0 1 1 0 1 1 1 1 Fibronectin type III domain BRCT_2 PF16589.5 KZN90337.1 - 0.0079 16.6 0.0 0.018 15.5 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Mitofilin PF09731.9 KZN90337.1 - 4.2 6.1 7.7 5.9 5.6 7.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Aminotran_1_2 PF00155.21 KZN90338.1 - 5e-75 252.9 0.0 5.7e-75 252.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Abhydrolase_3 PF07859.13 KZN90339.1 - 1.3e-56 191.9 0.0 1.6e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KZN90339.1 - 0.00029 20.4 0.0 0.012 15.1 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family MIase PF02426.16 KZN90339.1 - 0.022 14.9 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 Muconolactone delta-isomerase Lyase_1 PF00206.20 KZN90340.1 - 3.4e-111 371.6 0.0 5.5e-111 370.9 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KZN90340.1 - 8.2e-21 74.2 0.1 2.3e-20 72.7 0.1 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus Acetyltransf_1 PF00583.25 KZN90341.1 - 2.2e-10 40.8 0.1 2.9e-10 40.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KZN90341.1 - 5.1e-08 32.9 0.0 7.3e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KZN90341.1 - 9.3e-07 29.2 0.3 1.3e-06 28.7 0.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribosomal_L24e PF01246.20 KZN90342.1 - 1.1e-27 96.0 0.2 1.1e-27 96.0 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e UQ_con PF00179.26 KZN90343.1 - 4.4e-47 159.2 0.0 5e-47 159.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KZN90343.1 - 0.0003 20.5 0.0 0.00037 20.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KZN90343.1 - 0.015 15.2 0.0 0.03 14.2 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 KZN90343.1 - 0.15 12.4 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain WD40 PF00400.32 KZN90344.1 - 2.6e-08 34.4 15.6 0.0049 17.7 0.1 5.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 KZN90344.1 - 5.1e-06 26.0 16.4 5.1e-06 26.0 16.4 2.5 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_14 PF17978.1 KZN90344.1 - 0.69 10.4 4.4 1.4 9.4 4.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Redoxin PF08534.10 KZN90345.1 - 1.8e-35 121.8 0.0 2e-35 121.7 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KZN90345.1 - 4.7e-13 49.1 0.0 6.1e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family PS-DH PF14765.6 KZN90346.1 - 6.7e-65 219.3 0.0 1.4e-64 218.2 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 KZN90346.1 - 7.6e-58 196.0 0.0 2e-57 194.7 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KZN90346.1 - 3.7e-52 176.8 0.7 1.1e-51 175.3 0.7 1.9 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KZN90346.1 - 1.3e-45 156.3 0.0 2.4e-45 155.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Beta-lactamase PF00144.24 KZN90346.1 - 3.6e-42 144.8 0.0 7e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase Ketoacyl-synt_C PF02801.22 KZN90346.1 - 4e-32 110.7 0.0 1.2e-31 109.1 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 KZN90346.1 - 1.6e-20 74.5 0.0 3.4e-18 67.0 0.0 3.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 KZN90346.1 - 5.3e-18 65.6 0.0 1.6e-17 64.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KZN90346.1 - 2.2e-15 56.6 2.7 6.3e-15 55.1 1.5 2.2 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.26 KZN90346.1 - 1.1e-14 54.6 0.0 2.6e-13 50.1 0.0 3.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 KZN90346.1 - 1.4e-12 47.7 0.0 3.5e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KZN90346.1 - 4.6e-12 46.4 0.0 1.2e-11 45.1 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KZN90346.1 - 1.7e-11 44.7 0.0 2e-09 38.0 0.0 3.6 3 0 0 3 3 2 1 Methyltransferase domain adh_short_C2 PF13561.6 KZN90346.1 - 6.9e-11 42.1 0.8 1.8e-10 40.8 0.8 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 KZN90346.1 - 4.5e-09 36.5 0.0 1.3e-08 35.0 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.6 KZN90346.1 - 1.7e-08 34.4 0.0 4.7e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN90346.1 - 1.7e-08 35.0 0.0 9.4e-08 32.6 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.12 KZN90346.1 - 0.00021 21.1 0.1 0.00049 20.0 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.18 KZN90346.1 - 0.00046 19.6 0.0 0.00098 18.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 KZN90346.1 - 0.013 14.9 0.0 0.035 13.5 0.0 1.6 1 0 0 1 1 1 0 Thiolase, N-terminal domain Peptidase_S11 PF00768.20 KZN90346.1 - 0.053 13.0 0.1 0.093 12.1 0.1 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase DUF938 PF06080.12 KZN90346.1 - 0.056 13.2 0.0 0.36 10.5 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF938) DUF3419 PF11899.8 KZN90347.1 - 1.9e-155 517.8 0.0 2.5e-155 517.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 KZN90347.1 - 5.8e-12 45.8 0.0 6.2e-11 42.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN90347.1 - 2.4e-07 31.4 0.0 9.8e-07 29.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN90347.1 - 2.5e-07 31.3 0.0 3.2e-05 24.5 0.0 3.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN90347.1 - 1.6e-06 28.0 0.0 4.4e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN90347.1 - 4.3e-06 27.3 0.0 0.0012 19.4 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 KZN90347.1 - 2.2e-05 23.9 0.0 0.081 12.2 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KZN90347.1 - 0.0038 17.0 0.0 0.0091 15.8 0.0 1.6 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_28 PF02636.17 KZN90347.1 - 0.033 13.8 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MFS_1 PF07690.16 KZN90348.1 - 2.5e-44 151.7 57.4 1.6e-43 149.0 53.9 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN90348.1 - 3.9e-16 58.9 11.7 3.9e-16 58.9 11.7 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KZN90348.1 - 2.6e-15 55.9 19.8 4.3e-15 55.2 19.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KZN90348.1 - 0.15 10.3 14.5 0.13 10.5 10.4 2.6 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family P5CR_dimer PF14748.6 KZN90349.1 - 7.4e-30 103.2 3.4 8e-30 103.2 1.7 1.9 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KZN90349.1 - 2.7e-12 47.1 0.1 9.3e-12 45.4 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.24 KZN90350.1 - 2e-08 34.2 0.4 1.6e-05 24.7 0.1 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KZN90350.1 - 6.6e-05 23.1 0.1 0.00052 20.2 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KZN90350.1 - 0.0067 17.0 0.0 0.015 15.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KZN90350.1 - 0.013 14.8 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KZN90350.1 - 0.049 12.7 0.0 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KZN90350.1 - 0.065 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KZN90350.1 - 0.067 13.5 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.6 KZN90350.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KZN90350.1 - 0.13 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KZN90350.1 - 0.19 10.9 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain DUF1348 PF07080.11 KZN90352.1 - 2e-56 189.4 3.8 2.2e-56 189.3 3.5 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1348) DUF4440 PF14534.6 KZN90352.1 - 8.1e-06 26.2 0.4 1.1e-05 25.7 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 KZN90352.1 - 2.5e-05 24.9 1.0 4e-05 24.2 0.9 1.4 1 1 0 1 1 1 1 SnoaL-like domain Pkinase PF00069.25 KZN90353.1 - 6.9e-66 222.3 0.0 8.8e-65 218.7 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Fungal_KA1 PF16797.5 KZN90353.1 - 1.6e-38 131.0 0.6 3e-38 130.1 0.6 1.5 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 KZN90353.1 - 3.4e-35 121.6 0.0 1.7e-33 116.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KZN90353.1 - 7.7e-05 21.8 0.0 0.00016 20.8 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KZN90353.1 - 0.0002 21.4 0.1 0.008 16.1 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KZN90353.1 - 0.00075 18.9 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KZN90353.1 - 0.0028 17.0 0.0 0.0056 16.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 KZN90353.1 - 0.011 15.4 0.0 0.026 14.1 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Zn_clus PF00172.18 KZN90354.1 - 1.1e-08 35.1 6.9 1.5e-08 34.6 6.9 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2461 PF09365.10 KZN90355.1 - 1.6e-72 243.8 0.1 2.5e-39 135.4 0.0 2.1 2 0 0 2 2 2 2 Conserved hypothetical protein (DUF2461) ARPC4 PF05856.12 KZN90357.1 - 1.4e-75 252.5 4.0 1.6e-75 252.3 4.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) UCH PF00443.29 KZN90358.1 - 5.7e-53 180.0 0.1 7.5e-53 179.6 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KZN90358.1 - 1.7e-11 43.7 0.0 4.5e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family UCH_1 PF13423.6 KZN90358.1 - 1.7e-10 41.1 12.7 1.3e-09 38.1 12.7 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF4652 PF15525.6 KZN90358.1 - 0.2 11.4 6.8 0.42 10.4 6.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) 4HBT PF03061.22 KZN90359.1 - 4.6e-07 30.1 0.1 7.7e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily TRI12 PF06609.13 KZN90360.1 - 3.2e-38 131.5 27.8 3.9e-38 131.2 27.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KZN90360.1 - 8.9e-18 64.3 58.9 7.9e-17 61.2 54.2 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN90360.1 - 3.5e-11 42.6 9.7 3.5e-11 42.6 9.7 3.2 3 1 0 3 3 3 2 Sugar (and other) transporter POP1 PF06978.11 KZN90361.1 - 3.8e-73 245.8 20.6 7.4e-73 244.9 20.6 1.5 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KZN90361.1 - 2.7e-29 101.3 1.9 3.5e-29 101.0 0.3 2.1 2 0 0 2 2 2 1 POPLD (NUC188) domain DUF1690 PF07956.11 KZN90362.1 - 8.5e-39 133.2 5.0 8.3e-19 68.4 1.4 2.0 2 0 0 2 2 2 2 Protein of Unknown function (DUF1690) Apolipoprotein PF01442.18 KZN90362.1 - 0.17 11.7 8.4 0.55 10.1 3.3 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain MRFAP1 PF15155.6 KZN90362.1 - 0.24 11.9 6.9 0.3 11.6 1.3 2.7 2 1 0 2 2 2 0 MORF4 family-associated protein1 Matrilin_ccoil PF10393.9 KZN90362.1 - 0.34 10.8 4.6 4.2 7.3 2.2 2.6 2 1 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Hexokinase_2 PF03727.16 KZN90363.1 - 4.6e-80 268.5 0.0 6e-80 268.1 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KZN90363.1 - 2e-69 233.5 0.0 3.1e-69 232.9 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Aldo_ket_red PF00248.21 KZN90364.1 - 2.3e-69 233.8 0.0 2.9e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 KZN90365.1 - 2.1e-42 145.3 52.1 2.1e-42 145.3 52.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily EbsA PF17255.2 KZN90365.1 - 0.09 13.1 1.6 2.7 8.3 0.0 2.7 2 0 0 2 2 2 0 EbsA-like protein Trypan_PARP PF05887.11 KZN90365.1 - 2.1 8.3 7.5 0.26 11.3 2.7 2.0 2 1 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Mpv17_PMP22 PF04117.12 KZN90366.1 - 3.5e-13 49.6 0.3 8e-13 48.4 0.3 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family p450 PF00067.22 KZN90367.1 - 2.8e-65 220.9 0.0 3.7e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sdh_cyt PF01127.22 KZN90367.1 - 0.017 15.2 1.7 0.036 14.1 1.7 1.5 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit zf-C2HC5 PF06221.13 KZN90368.1 - 1e-21 76.7 4.7 1.6e-21 76.1 4.7 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Sgf11 PF08209.11 KZN90369.1 - 1.6e-06 27.6 0.6 1.6e-06 27.6 0.6 1.9 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.6 KZN90369.1 - 0.063 13.2 0.9 0.12 12.3 0.9 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Actin_micro PF17003.5 KZN90369.1 - 0.14 11.3 0.1 0.25 10.5 0.1 1.4 2 0 0 2 2 2 0 Putative actin-like family zf-C2H2_4 PF13894.6 KZN90369.1 - 1 10.4 3.7 1 10.4 0.5 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger RRN3 PF05327.11 KZN90370.1 - 0.014 13.9 1.6 0.017 13.7 1.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Acetyltransf_1 PF00583.25 KZN90370.1 - 0.064 13.5 0.0 0.26 11.5 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Ribosomal_60s PF00428.19 KZN90370.1 - 0.64 10.6 4.6 0.44 11.2 1.7 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein NAD_binding_6 PF08030.12 KZN90371.1 - 1.7e-21 77.0 0.0 4.3e-21 75.7 0.0 1.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KZN90371.1 - 6.5e-19 68.3 13.5 8.7e-18 64.6 10.9 2.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KZN90371.1 - 2.7e-14 53.2 0.0 8.1e-14 51.6 0.0 1.8 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KZN90371.1 - 0.0013 19.3 0.0 0.37 11.5 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain RNase_PH PF01138.21 KZN90372.1 - 1.2e-14 55.0 0.1 5.5e-14 52.8 0.1 2.0 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF4988 PF16378.5 KZN90372.1 - 0.11 12.1 1.1 0.21 11.2 0.4 1.6 2 0 0 2 2 2 0 Domain of unknown function Peptidase_A22B PF04258.13 KZN90373.1 - 3.4e-60 204.0 1.1 1.5e-59 201.9 1.1 1.9 1 1 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 KZN90373.1 - 1.3e-05 24.8 2.1 1.3e-05 24.8 2.1 2.0 2 1 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease DUF3216 PF11505.8 KZN90373.1 - 0.19 12.0 0.5 0.4 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3216) Pro_isomerase PF00160.21 KZN90374.1 - 1.3e-52 178.2 0.0 1.5e-52 178.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GDI PF00996.18 KZN90376.1 - 5.8e-26 91.0 0.0 1.3e-13 50.3 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KZN90376.1 - 0.027 14.7 0.0 0.072 13.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KZN90376.1 - 0.22 10.8 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Promethin PF16015.5 KZN90377.1 - 1.9e-11 43.8 12.4 4e-11 42.8 12.4 1.5 1 0 0 1 1 1 1 Promethin Aldedh PF00171.22 KZN90378.1 - 4.6e-76 256.2 0.0 5.7e-76 255.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Adeno_E3B PF03376.14 KZN90378.1 - 0.056 13.7 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E3B protein zf-DBF PF07535.12 KZN90378.1 - 0.13 12.4 1.1 3.6 7.8 0.0 2.7 2 0 0 2 2 2 0 DBF zinc finger Fungal_trans_2 PF11951.8 KZN90379.1 - 1.7e-70 237.8 4.6 2e-70 237.5 4.6 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2520 PF10728.9 KZN90379.1 - 0.14 11.9 0.3 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2520) DAO PF01266.24 KZN90380.1 - 8.6e-45 153.8 0.1 1e-44 153.6 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KZN90380.1 - 6e-06 25.7 0.0 0.021 14.1 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KZN90380.1 - 4.3e-05 23.6 0.0 0.07 13.1 0.0 2.7 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 KZN90380.1 - 0.00021 20.5 0.0 0.013 14.6 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A GMC_oxred_N PF00732.19 KZN90380.1 - 0.00026 20.5 0.0 0.034 13.5 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.6 KZN90380.1 - 0.00032 20.9 0.0 0.00075 19.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KZN90380.1 - 0.00052 19.2 0.1 0.0028 16.8 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.20 KZN90380.1 - 0.0058 16.7 0.0 0.029 14.4 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 KZN90380.1 - 0.019 14.2 0.0 3.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KZN90380.1 - 0.021 13.7 0.1 0.29 9.9 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase MFS_1 PF07690.16 KZN90381.1 - 2.5e-33 115.5 30.0 3.8e-33 114.9 30.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KZN90381.1 - 1.3e-06 28.0 5.6 1.3e-06 28.0 5.6 2.2 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB ESSS PF10183.9 KZN90381.1 - 0.34 11.2 1.1 7 6.9 0.0 3.3 4 0 0 4 4 4 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Hydantoinase_B PF02538.14 KZN90382.1 - 5.5e-199 661.9 0.3 7.7e-199 661.4 0.3 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KZN90382.1 - 1.8e-102 342.5 0.6 4.4e-102 341.3 0.1 1.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KZN90382.1 - 1.4e-60 204.0 2.2 4.8e-59 199.0 0.1 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.9 KZN90382.1 - 0.025 14.2 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature His_Phos_2 PF00328.22 KZN90383.1 - 1.4e-40 139.8 0.0 1.8e-40 139.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Nup35_RRM PF05172.13 KZN90384.1 - 0.00071 19.5 0.0 0.0018 18.2 0.0 1.6 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF1233 PF06806.12 KZN90384.1 - 0.15 11.7 0.1 0.3 10.7 0.1 1.5 1 0 0 1 1 1 0 Putative excisionase (DUF1233) NAC PF01849.18 KZN90385.1 - 4.9e-10 39.2 0.0 8.1e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 NAC domain MAGI_u1 PF16663.5 KZN90385.1 - 0.0079 16.3 0.1 0.012 15.7 0.1 1.2 1 0 0 1 1 1 1 Unstructured region on MAGI Med17 PF10156.9 KZN90385.1 - 0.023 13.4 0.1 0.023 13.4 0.1 1.0 1 0 0 1 1 1 0 Subunit 17 of Mediator complex T3SSipB PF16535.5 KZN90385.1 - 0.035 14.6 0.0 0.039 14.4 0.0 1.1 1 0 0 1 1 1 0 Type III cell invasion protein SipB Epimerase PF01370.21 KZN90386.1 - 2.1e-23 83.1 0.0 6.5e-23 81.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KZN90386.1 - 3.1e-12 46.5 0.0 8.3e-12 45.2 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KZN90386.1 - 4e-10 39.2 0.0 7.3e-10 38.3 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KZN90386.1 - 4e-08 33.4 0.0 1.1e-07 32.0 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KZN90386.1 - 2.6e-07 30.1 0.0 4.5e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 KZN90386.1 - 1.5e-05 24.3 0.0 2.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KZN90386.1 - 9.5e-05 21.7 0.0 0.00086 18.5 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KZN90386.1 - 0.17 11.4 0.1 1 8.9 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family adh_short PF00106.25 KZN90387.1 - 6.3e-24 84.5 0.0 6.9e-18 64.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KZN90387.1 - 9e-11 41.8 0.0 2.2e-09 37.2 0.0 2.1 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN90387.1 - 2.7e-08 33.9 0.0 4.8e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KZN90387.1 - 0.0011 18.2 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KZN90387.1 - 0.047 13.1 0.0 0.079 12.4 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family FSH1 PF03959.13 KZN90388.1 - 3.1e-34 118.5 0.0 4.1e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KZN90388.1 - 0.00022 21.9 0.0 0.00038 21.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KZN90388.1 - 0.09 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Synaptobrevin PF00957.21 KZN90389.1 - 2e-32 110.8 0.7 2.3e-32 110.6 0.7 1.0 1 0 0 1 1 1 1 Synaptobrevin Prominin PF05478.11 KZN90389.1 - 0.042 11.8 0.1 0.056 11.4 0.1 1.1 1 0 0 1 1 1 0 Prominin NAT PF04768.13 KZN90390.1 - 3e-56 189.7 0.3 6.8e-56 188.6 0.1 1.7 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 KZN90390.1 - 4.4e-31 107.8 0.0 1.7e-30 106.0 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 KZN90390.1 - 3.2e-29 102.2 0.0 6.2e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.20 KZN90390.1 - 0.052 13.7 0.0 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Rad21_Rec8_N PF04825.13 KZN90391.1 - 1.4e-30 105.7 0.0 3.1e-30 104.6 0.0 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KZN90391.1 - 0.0015 17.7 0.0 0.0048 16.2 0.0 1.8 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DUF3237 PF11578.8 KZN90392.1 - 3.7e-34 117.7 0.0 5.5e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.15 KZN90392.1 - 0.00014 21.8 3.9 0.081 13.0 0.3 2.4 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_2 PF12756.7 KZN90392.1 - 0.031 14.6 4.1 2.9 8.3 0.2 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn_Tnp_IS91 PF14319.6 KZN90392.1 - 0.63 10.1 11.5 0.8 9.8 2.2 2.3 2 0 0 2 2 2 0 Transposase zinc-binding domain PyrI_C PF02748.15 KZN90392.1 - 1 9.3 6.0 7.4 6.6 0.5 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Fungal_trans PF04082.18 KZN90393.1 - 0.0031 16.6 0.2 0.19 10.7 0.0 2.3 2 1 0 2 2 2 2 Fungal specific transcription factor domain Chitin_synth_1 PF01644.17 KZN90394.1 - 3.7e-69 231.9 0.0 5.4e-69 231.3 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 KZN90394.1 - 2.1e-27 96.0 0.3 3.1e-21 75.6 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 KZN90394.1 - 4.2e-27 93.9 0.1 1.3e-26 92.3 0.1 1.8 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 KZN90394.1 - 1e-09 38.6 0.0 1e-09 38.6 0.0 2.7 3 1 0 3 3 3 1 Glycosyl transferase family group 2 ICL PF00463.21 KZN90396.1 - 6.8e-188 625.4 0.0 7.8e-188 625.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KZN90396.1 - 1.1e-09 38.2 0.0 1.7e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Fungal_trans_2 PF11951.8 KZN90398.1 - 2.7e-56 191.0 0.3 3.7e-56 190.6 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain GST_N_3 PF13417.6 KZN90399.1 - 1.1e-09 38.5 0.0 2.1e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KZN90399.1 - 3.3e-08 33.7 0.0 8.9e-08 32.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KZN90399.1 - 5.6e-08 33.0 0.0 1e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KZN90399.1 - 1.7e-07 31.1 0.0 4.2e-07 29.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KZN90399.1 - 4.2e-07 30.1 0.0 6.2e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KZN90399.1 - 1.1e-06 28.7 0.0 1.6e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TPP_enzyme_N PF02776.18 KZN90400.1 - 2.2e-53 180.4 0.1 9e-53 178.4 0.0 2.1 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KZN90400.1 - 7.3e-45 152.5 0.1 2.2e-43 147.7 0.1 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KZN90400.1 - 7.4e-44 148.8 0.0 1.5e-43 147.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.16 KZN90400.1 - 0.0045 16.8 0.0 0.008 16.0 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Molybdopterin PF00384.22 KZN90400.1 - 0.15 11.0 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin oxidoreductase Aminotran_1_2 PF00155.21 KZN90401.1 - 1.7e-70 238.0 0.0 2.1e-70 237.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II EutQ PF06249.12 KZN90402.1 - 9.7e-12 44.9 0.0 1.2e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 KZN90402.1 - 8.3e-10 38.2 0.1 1.1e-09 37.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 KZN90402.1 - 2e-05 24.2 0.1 3e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Pirin PF02678.16 KZN90402.1 - 0.02 14.9 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Pirin Cupin_1 PF00190.22 KZN90402.1 - 0.039 13.6 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 Cupin Cupin_6 PF12852.7 KZN90402.1 - 0.12 12.1 0.0 0.49 10.1 0.0 1.7 1 1 0 2 2 2 0 Cupin Pkinase PF00069.25 KZN90403.1 - 6.6e-59 199.4 0.0 6.4e-58 196.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN90403.1 - 4.9e-28 98.1 0.4 2.5e-19 69.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KZN90403.1 - 0.00029 21.5 0.6 0.001 19.7 0.6 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 KZN90403.1 - 0.003 17.5 3.7 0.66 9.9 0.0 3.5 3 1 1 4 4 4 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KZN90403.1 - 0.0031 16.9 0.7 0.027 13.8 0.0 2.5 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 KZN90403.1 - 0.025 13.5 0.0 0.043 12.7 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KZN90403.1 - 0.089 12.1 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1687 PF07955.11 KZN90404.1 - 1.2e-26 93.7 0.0 1.4e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) OSCP PF00213.18 KZN90404.1 - 0.072 13.2 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit FAD_binding_8 PF08022.12 KZN90405.1 - 2.1e-20 72.8 0.0 4.1e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KZN90405.1 - 4.1e-20 72.2 15.1 7.9e-20 71.2 15.1 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KZN90405.1 - 2.4e-16 60.2 0.0 4.5e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ctr PF04145.15 KZN90406.1 - 6.6e-32 111.2 0.1 8.4e-32 110.8 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family AATase PF07247.12 KZN90408.1 - 1.6e-21 76.4 0.0 1.5e-20 73.3 0.0 2.0 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 KZN90408.1 - 0.026 13.2 0.1 0.073 11.7 0.1 1.6 1 1 0 1 1 1 0 Condensation domain WES_acyltransf PF03007.16 KZN90408.1 - 0.039 13.7 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Abhydrolase_2 PF02230.16 KZN90409.1 - 1.2e-47 162.5 0.0 1.5e-47 162.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KZN90409.1 - 2.2e-08 33.8 0.0 2.9e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KZN90409.1 - 2.2e-05 23.9 0.1 0.00087 18.6 0.0 2.2 1 1 1 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 KZN90409.1 - 0.0009 18.9 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family LIP PF03583.14 KZN90409.1 - 0.0041 16.5 0.0 0.11 11.8 0.0 2.1 2 0 0 2 2 2 1 Secretory lipase Abhydrolase_3 PF07859.13 KZN90409.1 - 0.0057 16.5 0.0 0.034 14.0 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 KZN90409.1 - 0.0068 16.3 0.3 0.25 11.3 0.0 2.1 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 KZN90409.1 - 0.0091 15.7 0.0 0.014 15.1 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.7 KZN90409.1 - 0.014 15.2 0.0 0.024 14.4 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 KZN90409.1 - 0.019 14.5 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF2920 PF11144.8 KZN90409.1 - 0.039 13.1 0.0 2.8 7.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) Abhydrolase_4 PF08386.10 KZN90409.1 - 0.056 13.6 0.0 0.082 13.0 0.0 1.2 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_6 PF12697.7 KZN90409.1 - 0.061 13.9 0.0 0.89 10.1 0.0 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 KZN90409.1 - 0.063 13.1 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.20 KZN90409.1 - 0.084 12.5 0.2 3.7 7.1 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold CBP4 PF07960.11 KZN90410.1 - 8.2e-29 100.1 2.7 1.1e-28 99.7 2.7 1.1 1 0 0 1 1 1 1 CBP4 Rgp1 PF08737.10 KZN90410.1 - 0.05 12.8 0.7 0.055 12.6 0.7 1.0 1 0 0 1 1 1 0 Rgp1 Trp_oprn_chp PF09534.10 KZN90410.1 - 0.069 12.9 0.7 0.091 12.5 0.2 1.5 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Mntp PF02659.15 KZN90410.1 - 0.21 11.3 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative manganese efflux pump Sel1 PF08238.12 KZN90411.1 - 2.3e-45 152.0 24.6 2.4e-07 31.2 0.1 7.5 7 0 0 7 7 7 7 Sel1 repeat TPR_20 PF14561.6 KZN90411.1 - 0.14 12.5 2.2 0.2 12.0 0.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat LigB PF02900.18 KZN90412.1 - 8.5e-35 120.1 0.0 1.1e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase L51_S25_CI-B8 PF05047.16 KZN90413.1 - 5.1e-13 48.7 0.0 6.4e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MPC PF03650.13 KZN90414.1 - 2.4e-49 166.1 0.7 3.2e-49 165.6 0.7 1.2 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers DUF2863 PF11062.8 KZN90414.1 - 0.014 13.8 2.0 0.4 9.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2863) Glyco_hydro_28 PF00295.17 KZN90415.1 - 3.9e-50 170.8 7.3 6.6e-50 170.0 7.3 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Transferase PF02458.15 KZN90416.1 - 3.5e-12 45.7 0.0 1.6e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 Transferase family FAD_binding_3 PF01494.19 KZN90418.1 - 2e-22 79.9 0.0 3.2e-11 43.1 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KZN90418.1 - 1.1e-05 24.8 0.0 0.0083 15.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN90418.1 - 0.00016 21.8 0.0 0.00047 20.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KZN90418.1 - 0.00019 21.1 0.0 0.0055 16.3 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KZN90418.1 - 0.00019 20.6 0.0 0.00039 19.6 0.0 1.4 1 1 0 1 1 1 1 Lycopene cyclase protein Amino_oxidase PF01593.24 KZN90418.1 - 0.0013 18.1 0.2 0.17 11.2 0.1 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KZN90418.1 - 0.0034 16.7 0.1 0.037 13.3 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KZN90418.1 - 0.0075 15.3 0.0 0.084 11.9 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.27 KZN90418.1 - 0.013 16.1 0.5 0.12 13.0 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KZN90418.1 - 0.014 14.6 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 KZN90418.1 - 0.029 13.5 0.1 0.044 12.8 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 KZN90418.1 - 0.082 11.7 0.1 9.2 5.0 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.18 KZN90418.1 - 0.1 12.9 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain UbiA PF01040.18 KZN90419.1 - 2.7e-31 108.8 14.8 4e-31 108.2 14.8 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family MerC PF03203.14 KZN90419.1 - 0.0014 19.1 2.8 0.0014 19.1 2.8 2.5 2 1 0 2 2 2 1 MerC mercury resistance protein adh_short_C2 PF13561.6 KZN90420.1 - 9.5e-49 166.1 1.7 1.2e-48 165.7 1.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN90420.1 - 2.8e-48 164.0 0.9 3.5e-48 163.7 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN90420.1 - 9.4e-07 28.9 2.9 8.3e-06 25.8 2.9 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KZN90420.1 - 0.0021 17.6 0.0 0.0033 16.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sarcoglycan_2 PF05510.13 KZN90420.1 - 0.0031 16.4 0.0 0.0039 16.0 0.0 1.1 1 0 0 1 1 1 1 Sarcoglycan alpha/epsilon Eno-Rase_NADH_b PF12242.8 KZN90420.1 - 0.11 12.3 0.5 0.3 10.9 0.5 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.21 KZN90421.1 - 6.9e-12 45.3 0.0 1.5e-11 44.2 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KZN90421.1 - 5.5e-09 35.4 0.0 7.3e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KZN90421.1 - 8e-07 29.1 0.1 1.2e-06 28.6 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KZN90421.1 - 1.3e-06 28.1 0.1 1.7e-06 27.7 0.1 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KZN90421.1 - 0.00015 21.4 0.2 0.00021 20.9 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KZN90421.1 - 0.00039 19.7 0.4 0.084 12.0 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein KR PF08659.10 KZN90421.1 - 0.0047 16.9 0.8 0.13 12.2 0.1 2.2 2 0 0 2 2 2 1 KR domain ketoacyl-synt PF00109.26 KZN90422.1 - 2.7e-73 246.7 0.3 5.9e-73 245.6 0.3 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KZN90422.1 - 2.5e-36 124.3 0.0 6.4e-36 123.0 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KZN90422.1 - 6.4e-24 84.7 0.0 1.1e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase HTH_51 PF18558.1 KZN90422.1 - 9e-21 73.6 0.0 2.4e-20 72.2 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain Acyl_transf_1 PF00698.21 KZN90422.1 - 5.8e-18 65.5 0.1 2.4e-16 60.1 0.0 2.4 2 0 0 2 2 2 1 Acyl transferase domain Methyltransf_12 PF08242.12 KZN90422.1 - 1.7e-17 64.0 0.0 5.4e-17 62.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KZN90422.1 - 1.2e-14 54.4 0.5 3e-14 53.1 0.5 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_3 PF07859.13 KZN90422.1 - 2.1e-14 53.9 0.1 2.6e-11 43.8 0.0 2.7 3 0 0 3 3 2 2 alpha/beta hydrolase fold SAT PF16073.5 KZN90422.1 - 3.2e-12 46.7 0.9 2.3e-09 37.4 0.1 3.2 2 1 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_25 PF13649.6 KZN90422.1 - 1.1e-11 45.3 0.0 4.4e-11 43.3 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN90422.1 - 7.6e-11 42.5 0.0 2.1e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN90422.1 - 1.4e-09 38.0 0.0 5.4e-09 36.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Peptidase_S9 PF00326.21 KZN90422.1 - 3.1e-08 33.4 0.0 1.7e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Methyltransf_31 PF13847.6 KZN90422.1 - 5.5e-07 29.5 0.0 1.5e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KZN90422.1 - 1.7e-06 28.4 0.0 5.3e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension DLH PF01738.18 KZN90422.1 - 6.3e-06 25.9 0.0 0.00065 19.3 0.0 3.2 3 0 0 3 3 3 1 Dienelactone hydrolase family Thiolase_N PF00108.23 KZN90422.1 - 2.2e-05 24.0 1.7 2.6e-05 23.7 0.3 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.7 KZN90422.1 - 0.00013 22.7 2.5 0.00014 22.6 0.8 2.0 2 0 0 2 2 1 1 Alpha/beta hydrolase family Ubie_methyltran PF01209.18 KZN90422.1 - 0.00028 20.3 0.0 0.00064 19.1 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KZN90422.1 - 0.00098 18.9 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase LIP PF03583.14 KZN90422.1 - 0.0044 16.4 0.0 0.018 14.4 0.0 1.9 2 0 0 2 2 2 1 Secretory lipase Abhydrolase_2 PF02230.16 KZN90422.1 - 0.014 15.2 0.0 0.092 12.5 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KZN90422.1 - 0.014 14.7 0.1 0.087 12.1 0.0 2.3 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 KZN90422.1 - 0.034 14.3 0.0 0.096 12.8 0.0 1.7 1 0 0 1 1 1 0 Thioesterase domain ABC2_membrane PF01061.24 KZN90423.1 - 7.5e-73 244.4 55.4 1.5e-39 135.6 20.3 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KZN90423.1 - 7e-39 133.5 0.0 1e-17 64.9 0.0 3.1 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 KZN90423.1 - 5.3e-29 100.0 2.2 6.2e-25 86.9 0.0 3.2 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 KZN90423.1 - 2.2e-06 27.0 11.5 2.2e-06 27.0 11.5 3.5 2 2 1 3 3 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KZN90423.1 - 1.1e-05 25.5 0.0 0.00069 19.6 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KZN90423.1 - 6.9e-05 23.0 0.1 0.029 14.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KZN90423.1 - 0.00028 20.5 0.1 0.0034 17.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KZN90423.1 - 0.00065 20.1 0.1 0.051 14.0 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 KZN90423.1 - 0.0012 18.9 0.0 1.2 9.3 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 KZN90423.1 - 0.003 18.1 0.0 0.032 14.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KZN90423.1 - 0.008 16.6 0.1 0.045 14.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KZN90423.1 - 0.0084 16.0 0.2 2.5 8.0 0.0 3.3 3 0 0 3 3 3 1 NACHT domain RNA_helicase PF00910.22 KZN90423.1 - 0.0096 16.3 0.0 1.9 8.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_29 PF13555.6 KZN90423.1 - 0.01 15.6 0.8 0.82 9.5 0.1 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain cobW PF02492.19 KZN90423.1 - 0.015 14.9 0.5 0.05 13.2 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KZN90423.1 - 0.016 14.9 0.1 0.37 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_trans_N PF14510.6 KZN90423.1 - 0.021 15.5 0.0 0.047 14.3 0.0 1.6 1 0 0 1 1 1 0 ABC-transporter N-terminal Ploopntkinase3 PF18751.1 KZN90423.1 - 0.065 13.1 0.1 6.7 6.6 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 SMC_N PF02463.19 KZN90423.1 - 0.14 11.6 0.0 0.83 9.0 0.0 2.2 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA PF00004.29 KZN90423.1 - 0.18 12.2 0.0 6.2 7.2 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KZN90423.1 - 0.22 11.8 1.3 0.97 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain p450 PF00067.22 KZN90424.1 - 1.8e-41 142.4 0.0 2.3e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Arg_decarb_HB PF17810.1 KZN90424.1 - 0.036 14.3 2.3 0.23 11.7 0.1 2.8 4 0 0 4 4 4 0 Arginine decarboxylase helical bundle domain Phage_holin_6_1 PF09682.10 KZN90424.1 - 0.083 13.3 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Pyr_redox_2 PF07992.14 KZN90425.1 - 6.3e-20 71.6 0.0 9.6e-13 48.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KZN90425.1 - 0.0026 16.9 0.0 1.7 7.6 0.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A K_oxygenase PF13434.6 KZN90425.1 - 0.0026 16.9 0.0 0.012 14.8 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KZN90425.1 - 0.011 15.0 0.1 3.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KZN90425.1 - 0.014 14.2 0.0 0.036 12.8 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 KZN90425.1 - 0.039 13.0 0.3 0.55 9.2 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 KZN90425.1 - 0.044 13.8 0.7 4.6 7.2 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding Fungal_trans PF04082.18 KZN90426.1 - 4.8e-10 38.9 0.4 8.3e-10 38.1 0.4 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN90426.1 - 1.9e-07 31.1 9.1 1.9e-07 31.1 9.1 2.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 KZN90426.1 - 2.1e-05 24.7 14.5 0.00027 21.2 3.0 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KZN90426.1 - 3.3e-05 24.1 13.7 0.0021 18.4 5.4 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2HE PF16278.5 KZN90426.1 - 0.16 12.4 2.5 0.19 12.2 0.6 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_4 PF13894.6 KZN90426.1 - 0.62 11.1 24.2 0.064 14.1 4.0 3.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.7 KZN90426.1 - 3.2 8.2 6.3 0.93 10.0 0.2 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FMO-like PF00743.19 KZN90427.1 - 8.4e-14 50.9 0.8 1.1e-12 47.1 0.2 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KZN90427.1 - 5.5e-13 49.0 0.0 1.3e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KZN90427.1 - 9.5e-12 44.7 0.0 1.6e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KZN90427.1 - 3.1e-09 36.4 0.3 1.4e-05 24.4 0.1 3.4 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KZN90427.1 - 2.5e-08 33.6 0.3 1.1e-06 28.1 0.2 3.1 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KZN90427.1 - 1.4e-05 24.5 0.0 0.0017 17.6 0.0 2.3 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 KZN90427.1 - 1.5e-05 25.1 0.1 0.0013 18.8 0.0 3.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 KZN90427.1 - 0.00028 20.6 0.3 0.0082 15.8 0.1 2.7 2 1 1 3 3 3 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KZN90427.1 - 0.038 14.0 0.0 62 3.6 0.0 3.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KZN90427.1 - 0.057 12.5 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KZN90427.1 - 0.077 11.7 0.0 0.18 10.5 0.0 1.6 1 0 0 1 1 1 0 HI0933-like protein zf-met PF12874.7 KZN90428.1 - 2.2e-22 78.7 33.6 1.2e-05 25.6 1.8 8.0 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KZN90428.1 - 9e-19 67.3 33.8 2.4e-07 30.8 2.0 7.9 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KZN90428.1 - 6.2e-18 63.9 29.6 0.02 15.7 0.1 8.5 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2 PF00096.26 KZN90428.1 - 1.1e-17 63.4 37.4 0.0017 18.7 0.6 8.4 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KZN90428.1 - 2.4e-14 53.5 35.7 0.037 14.4 0.1 7.9 2 2 6 8 8 8 6 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KZN90428.1 - 7.5e-10 38.6 31.5 0.00094 19.1 0.1 8.0 8 0 0 8 8 8 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KZN90428.1 - 1.8e-05 25.0 33.8 0.37 11.3 0.0 8.5 8 0 0 8 8 8 3 Zinc-finger double domain zf-C2H2_11 PF16622.5 KZN90428.1 - 0.001 18.8 0.1 0.071 12.9 0.0 5.1 6 0 0 6 6 6 2 zinc-finger C2H2-type zinc_ribbon_9 PF14369.6 KZN90428.1 - 0.019 15.2 0.2 0.019 15.2 0.2 4.4 5 0 0 5 5 4 0 zinc-ribbon zf-C2H2_8 PF15909.5 KZN90428.1 - 0.042 14.1 20.1 1.2 9.5 1.4 4.4 2 1 2 4 4 4 0 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 KZN90428.1 - 0.067 13.1 28.1 0.48 10.4 0.2 6.6 7 0 0 7 7 7 0 zinc-finger of a C2HC-type Penicillinase_R PF03965.16 KZN90428.1 - 0.081 13.3 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Penicillinase repressor zf_ZIC PF18366.1 KZN90428.1 - 2 8.6 12.6 9.1 6.5 0.1 5.4 6 0 0 6 6 6 0 Zic proteins zinc finger domain CFEM PF05730.11 KZN90429.1 - 0.098 12.8 6.9 0.21 11.7 6.9 1.5 1 0 0 1 1 1 0 CFEM domain VSP PF03302.13 KZN90430.1 - 4.2e-05 22.6 3.4 7.2e-05 21.8 3.4 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein Cu_bind_like PF02298.17 KZN90430.1 - 0.066 13.2 0.2 0.24 11.4 0.2 2.0 1 1 0 1 1 1 0 Plastocyanin-like domain EphA2_TM PF14575.6 KZN90430.1 - 0.13 13.2 0.0 0.23 12.4 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3990 PF13151.6 KZN90431.1 - 0.00048 19.8 0.0 0.00082 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3990) Pkinase PF00069.25 KZN90433.1 - 3.9e-26 92.0 0.0 2.2e-25 89.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN90433.1 - 5.6e-10 38.9 0.0 5.2e-09 35.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase ILVD_EDD PF00920.21 KZN90434.1 - 2.5e-209 696.2 0.5 2.8e-209 696.0 0.5 1.0 1 0 0 1 1 1 1 Dehydratase family 5_nucleotid_C PF02872.18 KZN90434.1 - 0.0037 17.5 0.0 0.016 15.5 0.0 2.1 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 KZN90435.1 - 1.6e-31 109.5 0.4 3.7e-31 108.4 0.4 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KZN90435.1 - 1.9e-18 67.2 0.1 4.5e-18 66.0 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KZN90435.1 - 3.2e-18 65.7 0.0 6.1e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KZN90435.1 - 4.6e-14 52.8 1.6 1.6e-13 51.1 0.2 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Spc7_C2 PF15577.6 KZN90435.1 - 0.19 11.8 0.0 0.56 10.3 0.0 1.7 1 0 0 1 1 1 0 Spc7_C2 SSB PF00436.25 KZN90437.1 - 0.051 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Single-strand binding protein family GFRP PF06399.13 KZN90437.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.6 2 0 0 2 2 2 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) FAD_binding_4 PF01565.23 KZN90438.1 - 6.8e-24 84.2 3.4 1.2e-23 83.4 3.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KZN90438.1 - 1.4e-10 41.1 1.8 2.8e-10 40.1 1.8 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KZN90438.1 - 0.029 13.8 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Aldo_ket_red PF00248.21 KZN90439.1 - 1.6e-40 139.1 0.0 2e-40 138.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Abhydrolase_6 PF12697.7 KZN90440.1 - 2.3e-22 80.7 1.6 2.8e-22 80.4 1.6 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KZN90440.1 - 5.4e-05 22.6 0.0 0.1 11.9 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KZN90440.1 - 0.0013 18.7 0.5 0.0015 18.4 0.5 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KZN90440.1 - 0.19 11.8 0.4 0.52 10.4 0.1 1.8 3 0 0 3 3 3 0 Thioesterase domain PGAP1 PF07819.13 KZN90440.1 - 0.2 11.3 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Methyltransf_25 PF13649.6 KZN90442.1 - 7.2e-07 29.8 0.0 2.7e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN90442.1 - 4.8e-06 26.4 0.0 7.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN90442.1 - 8.9e-05 23.2 0.0 0.00024 21.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN90442.1 - 0.00091 19.1 0.0 0.0016 18.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN90442.1 - 0.0048 17.5 0.0 0.0093 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain p450 PF00067.22 KZN90443.1 - 1.1e-48 166.1 0.0 1.4e-48 165.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 KZN90444.1 - 1.5e-15 57.2 0.2 5.5e-13 48.8 0.6 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KZN90444.1 - 1.5e-07 31.3 0.3 5e-06 26.2 0.2 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN90444.1 - 6.1e-07 29.5 0.8 8.9e-07 29.0 0.8 1.2 1 0 0 1 1 1 1 KR domain AMP-binding PF00501.28 KZN90445.1 - 2.6e-65 220.7 0.0 3.4e-65 220.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KZN90445.1 - 0.04 14.9 0.0 0.086 13.8 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 KZN90447.1 - 4.9e-19 68.4 0.1 2.8e-18 65.9 0.1 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN90447.1 - 1e-08 35.1 10.7 1.9e-08 34.3 10.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APC_rep PF18797.1 KZN90447.1 - 0.03 15.2 0.6 0.17 12.9 0.0 2.3 2 0 0 2 2 2 0 Adenomatous polyposis coli (APC) repeat FAD_binding_7 PF03441.14 KZN90448.1 - 2.8e-81 271.9 1.1 2.8e-81 271.9 1.1 1.6 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KZN90448.1 - 2.4e-42 144.7 0.1 4.1e-42 144.0 0.1 1.4 1 0 0 1 1 1 1 DNA photolyase Na_H_Exchanger PF00999.21 KZN90450.1 - 2.7e-53 181.1 43.6 3.9e-53 180.6 43.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3446 PF11928.8 KZN90450.1 - 0.022 15.1 1.8 3.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain Aminotran_4 PF01063.19 KZN90451.1 - 5.1e-22 78.8 0.0 6.3e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV BNR_2 PF13088.6 KZN90451.1 - 0.019 14.3 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 BNR repeat-like domain ADH_N PF08240.12 KZN90452.1 - 8.9e-27 93.1 2.0 1.5e-26 92.4 2.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN90452.1 - 2.4e-12 47.0 0.0 2.2e-07 30.9 0.0 2.6 2 0 0 2 2 2 2 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KZN90452.1 - 0.0012 18.3 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N_assoc PF13823.6 KZN90452.1 - 0.056 13.4 0.7 0.12 12.3 0.7 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.21 KZN90452.1 - 0.062 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pkinase PF00069.25 KZN90453.1 - 2.4e-40 138.6 0.0 8.2e-40 136.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 KZN90453.1 - 4.4e-40 136.8 0.0 1.2e-39 135.4 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 KZN90453.1 - 5.4e-20 71.8 0.0 1.5e-19 70.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Cytokin_check_N PF10407.9 KZN90453.1 - 0.00028 20.8 0.0 0.00076 19.4 0.0 1.7 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus PQQ PF01011.21 KZN90453.1 - 0.0021 17.9 0.0 1.1 9.3 0.0 2.9 2 0 0 2 2 2 1 PQQ enzyme repeat PQQ_2 PF13360.6 KZN90453.1 - 0.0042 16.7 0.4 0.19 11.3 0.1 2.4 1 1 1 3 3 3 2 PQQ-like domain Kdo PF06293.14 KZN90453.1 - 0.017 14.4 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KZN90453.1 - 0.053 13.0 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF5305 PF17231.2 KZN90453.1 - 6 6.2 5.6 0.91 8.9 0.1 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5305) Glyco_hydro_76 PF03663.14 KZN90454.1 - 4.4e-141 470.7 19.6 5.1e-141 470.4 19.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Cloacin_immun PF03513.14 KZN90454.1 - 0.01 16.2 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 Cloacin immunity protein Cpn60_TCP1 PF00118.24 KZN90455.1 - 1.6e-143 478.9 12.8 1.9e-143 478.7 12.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 KZN90455.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat CO_deh_flav_C PF03450.17 KZN90455.1 - 0.14 12.3 2.0 0.77 10.0 0.2 2.7 2 0 0 2 2 2 0 CO dehydrogenase flavoprotein C-terminal domain Pro_isomerase PF00160.21 KZN90456.1 - 1.1e-49 168.7 0.1 2.2e-49 167.8 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KZN90456.1 - 3.2e-13 49.9 0.2 0.0016 19.2 0.0 5.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KZN90456.1 - 0.028 13.4 0.1 0.8 8.6 0.0 2.6 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KZN90456.1 - 0.086 13.1 0.0 23 5.4 0.0 3.2 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain TMEM154 PF15102.6 KZN90457.1 - 0.00084 19.3 0.1 0.0025 17.7 0.0 1.8 2 0 0 2 2 2 1 TMEM154 protein family DUF4381 PF14316.6 KZN90457.1 - 0.0051 17.1 0.5 0.011 16.0 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) Synaptobrevin PF00957.21 KZN90457.1 - 0.034 14.0 0.2 0.063 13.1 0.2 1.4 1 0 0 1 1 1 0 Synaptobrevin BatD PF13584.6 KZN90457.1 - 0.036 12.9 0.1 0.05 12.4 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF2207 PF09972.9 KZN90457.1 - 0.049 12.4 0.0 0.06 12.1 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3619 PF12279.8 KZN90457.1 - 0.056 13.8 0.1 0.11 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) TMCO5 PF14992.6 KZN90457.1 - 0.21 11.1 0.0 0.26 10.8 0.0 1.1 1 0 0 1 1 1 0 TMCO5 family Kei1 PF08552.11 KZN90457.1 - 0.25 11.2 2.9 0.44 10.4 2.9 1.4 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 LapA_dom PF06305.11 KZN90457.1 - 5 7.0 5.6 0.79 9.6 0.2 2.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain MFS_1 PF07690.16 KZN90459.1 - 7.3e-25 87.6 32.2 4e-23 81.9 32.2 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4499 PF14934.6 KZN90459.1 - 0.26 11.6 3.1 0.61 10.4 2.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4499) Far-17a_AIG1 PF04750.14 KZN90460.1 - 9.3e-66 221.0 9.6 1.1e-65 220.8 9.6 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Gaa1 PF04114.14 KZN90460.1 - 0.009 15.1 2.7 0.0099 14.9 2.7 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Fungal_trans_2 PF11951.8 KZN90461.1 - 1.8e-52 178.4 0.1 4.5e-52 177.1 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN90461.1 - 1.4e-09 38.0 7.9 2.5e-09 37.1 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ECH_1 PF00378.20 KZN90462.1 - 4.3e-44 150.7 0.0 5.7e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KZN90462.1 - 3.1e-22 79.5 0.2 3.1e-21 76.2 0.3 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pam17 PF08566.10 KZN90463.1 - 3.8e-66 222.0 0.0 4.9e-66 221.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Adeno_PV PF03910.13 KZN90463.1 - 0.043 12.5 3.5 0.081 11.6 3.5 1.4 1 0 0 1 1 1 0 Adenovirus minor core protein PV Defensin_2 PF01097.18 KZN90464.1 - 9.7e-06 25.4 8.2 1.5e-05 24.8 8.2 1.4 1 1 0 1 1 1 1 Arthropod defensin SLR1-BP PF07333.12 KZN90464.1 - 0.036 14.5 4.6 0.05 14.0 4.6 1.2 1 0 0 1 1 1 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) DUF3602 PF12223.8 KZN90465.1 - 1.5e-16 60.7 4.9 2.8e-14 53.5 0.4 2.9 2 2 1 3 3 3 2 Protein of unknown function (DUF3602) ATG16 PF08614.11 KZN90465.1 - 0.0032 17.7 2.4 0.0038 17.5 2.4 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Fungal_trans_2 PF11951.8 KZN90466.1 - 7.5e-08 31.6 0.0 1.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Velvet PF11754.8 KZN90467.1 - 4.5e-94 315.1 0.0 5.7e-94 314.7 0.0 1.1 1 0 0 1 1 1 1 Velvet factor DUF2076 PF09849.9 KZN90467.1 - 0.98 9.4 6.2 1.5 8.8 6.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) WD40 PF00400.32 KZN90469.1 - 5e-59 194.9 26.7 8.6e-11 42.2 0.1 9.1 9 0 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN90469.1 - 3.3e-17 62.5 6.5 0.00045 20.5 0.1 6.0 2 2 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KZN90469.1 - 2.4e-08 34.1 0.5 0.01 15.8 0.0 3.5 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KZN90469.1 - 5.6e-07 28.8 0.9 0.081 11.9 0.0 4.8 3 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KZN90469.1 - 1.8e-05 23.6 6.1 0.49 9.0 0.1 5.3 4 2 1 5 5 5 2 Nucleoporin Nup120/160 NLE PF08154.12 KZN90469.1 - 3.4e-05 24.3 0.0 7.2e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain WD40_like PF17005.5 KZN90469.1 - 0.0072 15.7 0.0 17 4.6 0.0 3.8 5 0 0 5 5 5 1 WD40-like domain FAD_binding_9 PF08021.11 KZN90469.1 - 0.014 15.6 0.0 0.11 12.7 0.0 2.3 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain DUF4550 PF15084.6 KZN90469.1 - 0.026 14.9 0.1 0.29 11.6 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4550) 120_Rick_ant PF12574.8 KZN90469.1 - 0.063 12.5 0.4 0.45 9.7 0.0 2.2 2 0 0 2 2 2 0 120 KDa Rickettsia surface antigen MutS_III PF05192.18 KZN90470.1 - 1.4e-26 93.9 1.6 2.2e-26 93.3 1.6 1.3 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 KZN90470.1 - 1.1e-08 35.5 0.1 3.1e-08 34.0 0.1 1.8 1 1 0 1 1 1 1 MutS domain II MutS_V PF00488.21 KZN90471.1 - 9.9e-63 211.6 0.1 1.5e-62 211.0 0.1 1.2 1 0 0 1 1 1 1 MutS domain V MutS_IV PF05190.18 KZN90471.1 - 9.5e-06 25.9 0.0 2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV MutS_III PF05192.18 KZN90471.1 - 2.6e-05 24.6 0.2 9e-05 22.8 0.0 1.9 2 1 0 2 2 2 1 MutS domain III AAA_30 PF13604.6 KZN90471.1 - 0.00088 19.0 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF4392 PF14336.6 KZN90471.1 - 0.1 12.0 0.0 0.25 10.8 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4392) zf-C3HC4_3 PF13920.6 KZN90472.1 - 2.7e-07 30.4 8.9 2.7e-07 30.4 8.9 3.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KZN90472.1 - 0.0048 16.7 10.3 0.0048 16.7 10.3 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Tudor-knot PF11717.8 KZN90472.1 - 2.9 7.9 4.5 0.62 10.0 0.5 1.9 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain SWIB PF02201.18 KZN90473.1 - 3.2e-29 100.6 0.2 7e-29 99.5 0.2 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 KZN90473.1 - 3e-14 52.7 0.9 5.8e-14 51.8 0.9 1.5 1 0 0 1 1 1 1 DEK C terminal domain POM121 PF15229.6 KZN90473.1 - 4.3 6.9 18.1 0.78 9.4 10.4 2.6 1 1 2 3 3 3 0 POM121 family Ndc1_Nup PF09531.10 KZN90473.1 - 4.3 5.9 5.3 4.9 5.7 5.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup eIF2A PF08662.11 KZN90474.1 - 4.6e-37 127.8 6.0 7e-34 117.4 4.3 4.0 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 KZN90474.1 - 3.7e-06 26.7 0.0 7.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 KZN90474.1 - 0.014 16.2 1.0 5.8 8.0 0.1 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat CAP PF00188.26 KZN90475.1 - 2e-20 73.9 5.6 7.9e-20 72.0 5.6 1.8 1 1 0 1 1 1 1 Cysteine-rich secretory protein family PgaPase_1 PF06162.12 KZN90475.1 - 0.16 11.7 0.0 0.89 9.3 0.0 1.9 2 0 0 2 2 2 0 Putative pyroglutamyl peptidase PgaPase_1 Sec10 PF07393.11 KZN90476.1 - 2.2e-183 611.5 1.1 2.5e-183 611.3 1.1 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 KZN90476.1 - 1.9e-05 24.5 0.0 4.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN90476.1 - 0.002 18.0 0.0 0.0043 16.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain Cytochrom_C1 PF02167.15 KZN90477.1 - 5.8e-91 304.1 0.0 7.4e-91 303.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KZN90477.1 - 0.0055 17.0 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KZN90477.1 - 0.19 12.9 1.2 0.86 10.8 0.2 2.6 3 1 0 3 3 3 0 Cytochrome c AIG2_2 PF13772.6 KZN90478.1 - 0.0053 17.1 0.0 0.028 14.8 0.0 2.1 2 0 0 2 2 2 1 AIG2-like family DAHP_synth_1 PF00793.20 KZN90480.1 - 2.5e-101 338.2 0.0 3.1e-101 337.9 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family F-box-like PF12937.7 KZN90481.1 - 1.7e-06 27.8 2.1 4e-06 26.6 1.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KZN90481.1 - 7.5e-05 22.5 0.1 0.00036 20.3 0.1 2.2 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KZN90481.1 - 0.06 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 F-box RSN1_7TM PF02714.15 KZN90483.1 - 3.7e-80 269.2 19.7 3.7e-80 269.2 19.7 1.5 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KZN90483.1 - 1.4e-41 142.6 0.0 1.9e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KZN90483.1 - 1.2e-40 138.8 0.2 4.4e-40 137.0 0.2 2.0 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF3545 PF12065.8 KZN90483.1 - 0.09 12.8 1.3 0.72 9.9 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3545) Anoctamin PF04547.12 KZN90483.1 - 2.1 7.1 11.5 0.01 14.7 1.1 2.2 3 0 0 3 3 3 0 Calcium-activated chloride channel AbiEii PF08843.11 KZN90484.1 - 0.00053 20.0 0.1 0.0046 16.9 0.1 2.0 1 1 0 1 1 1 1 Nucleotidyl transferase AbiEii toxin, Type IV TA system DMP12 PF16779.5 KZN90485.1 - 0.11 12.5 0.1 6.2 6.8 0.1 2.2 2 0 0 2 2 2 0 DNA-mimic protein hDGE_amylase PF14701.6 KZN90486.1 - 4.4e-182 606.1 0.0 5.6e-182 605.7 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KZN90486.1 - 5.2e-117 391.0 0.0 8.2e-117 390.4 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KZN90486.1 - 1.9e-83 280.0 0.0 2.9e-83 279.4 0.0 1.3 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KZN90486.1 - 6e-29 100.0 0.0 1.3e-28 98.9 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 KZN90486.1 - 0.0097 15.5 0.0 0.025 14.2 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, catalytic domain NAD_Gly3P_dh_N PF01210.23 KZN90487.1 - 1.9e-47 161.2 0.1 4.1e-47 160.0 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KZN90487.1 - 8.3e-41 139.6 0.2 1.3e-40 139.0 0.2 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus SLX9 PF15341.6 KZN90488.1 - 5e-32 111.1 11.5 6e-32 110.8 11.5 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Neugrin PF06413.11 KZN90488.1 - 0.0056 16.7 1.7 0.0078 16.3 1.7 1.2 1 0 0 1 1 1 1 Neugrin AAA_2 PF07724.14 KZN90489.1 - 2.1e-36 125.6 0.0 2.2e-35 122.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KZN90489.1 - 2.2e-14 54.0 0.0 4.8e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KZN90489.1 - 1.4e-07 31.4 0.0 3.5e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KZN90489.1 - 6.3e-06 26.2 0.0 1.4e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KZN90489.1 - 0.00022 20.7 0.2 0.013 14.9 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KZN90489.1 - 0.00035 20.3 0.0 0.095 12.4 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 KZN90489.1 - 0.00049 20.4 0.5 0.012 15.8 0.5 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KZN90489.1 - 0.0013 18.5 0.1 0.031 14.0 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KZN90489.1 - 0.0038 17.0 0.1 0.0082 15.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KZN90489.1 - 0.0056 16.4 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 KZN90489.1 - 0.0058 17.0 3.3 0.023 15.1 0.1 2.9 2 1 2 4 4 4 1 AAA ATPase domain AAA_18 PF13238.6 KZN90489.1 - 0.0087 16.6 0.0 0.022 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KZN90489.1 - 0.045 13.9 0.5 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KZN90489.1 - 0.047 14.1 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.6 KZN90489.1 - 0.065 13.4 0.0 0.28 11.3 0.0 2.0 2 1 0 2 2 2 0 Sigma-54 interaction domain TsaE PF02367.17 KZN90489.1 - 0.069 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KZN90489.1 - 0.071 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region MCM PF00493.23 KZN90489.1 - 0.073 12.2 0.1 0.15 11.1 0.1 1.4 1 0 0 1 1 1 0 MCM P-loop domain NACHT PF05729.12 KZN90489.1 - 0.082 12.8 0.2 1.2 9.1 0.2 2.3 1 1 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 KZN90489.1 - 0.11 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Chromo PF00385.24 KZN90490.1 - 1e-06 28.5 0.8 2.4e-06 27.3 0.8 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ras PF00071.22 KZN90491.1 - 2.5e-54 183.2 0.3 3.2e-54 182.9 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KZN90491.1 - 1.2e-26 93.3 0.1 1.8e-26 92.7 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KZN90491.1 - 8e-10 38.4 0.1 1e-09 38.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KZN90491.1 - 0.00098 18.7 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AEP1 PF17049.5 KZN90491.1 - 0.1 11.6 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 ATPase expression protein 1 Brix PF04427.18 KZN90492.1 - 1.4e-29 103.6 0.0 1.8e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Brix domain PfkB PF00294.24 KZN90493.1 - 8.3e-17 61.4 0.0 5.1e-16 58.8 0.0 2.0 1 1 0 1 1 1 1 pfkB family carbohydrate kinase TFIIA PF03153.13 KZN90494.1 - 0.045 13.7 71.1 0.085 12.8 71.0 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SAPS PF04499.15 KZN90494.1 - 0.046 12.5 16.1 0.057 12.2 16.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SID-1_RNA_chan PF13965.6 KZN90494.1 - 0.18 10.2 10.3 0.22 9.9 10.3 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Endostatin PF06482.11 KZN90494.1 - 0.62 9.5 26.1 1.1 8.7 26.1 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF3292 PF11696.8 KZN90494.1 - 2.1 6.6 22.7 3.1 6.1 22.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) eIF-3_zeta PF05091.12 KZN90494.1 - 2.1 7.2 38.1 0.097 11.6 32.8 1.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Gti1_Pac2 PF09729.9 KZN90494.1 - 2.4 8.2 23.2 1.5 8.9 21.3 1.7 2 0 0 2 2 2 0 Gti1/Pac2 family GREB1 PF15782.5 KZN90494.1 - 3.3 4.7 28.4 4.7 4.2 28.4 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AUX_IAA PF02309.16 KZN90494.1 - 3.8 7.3 17.5 7.2 6.4 17.5 1.5 1 0 0 1 1 1 0 AUX/IAA family Presenilin PF01080.17 KZN90494.1 - 5 5.8 40.3 8 5.1 40.3 1.3 1 0 0 1 1 1 0 Presenilin DUF1387 PF07139.11 KZN90494.1 - 7.5 6.2 33.1 0.84 9.3 28.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) Abp2 PF09441.10 KZN90497.1 - 1.3e-86 289.0 0.0 2.1e-86 288.3 0.0 1.3 1 0 0 1 1 1 1 ARS binding protein 2 TENA_THI-4 PF03070.16 KZN90497.1 - 0.071 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 TENA/THI-4/PQQC family Med9 PF07544.13 KZN90497.1 - 0.081 13.0 1.6 0.12 12.5 0.3 1.9 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Surfac_D-trimer PF09006.11 KZN90497.1 - 0.23 11.4 1.6 0.47 10.4 1.6 1.5 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation F-box-like PF12937.7 KZN90498.1 - 0.00052 19.9 1.7 0.0012 18.7 1.7 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KZN90498.1 - 0.056 13.9 0.4 0.056 13.9 0.4 4.0 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) WW PF00397.26 KZN90499.1 - 8e-05 22.6 6.9 9e-05 22.5 4.3 2.4 2 0 0 2 2 2 1 WW domain DUF5327 PF17261.2 KZN90500.1 - 0.014 16.1 2.0 0.021 15.6 2.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5327) SLC12 PF03522.15 KZN90500.1 - 0.079 12.0 0.2 0.088 11.8 0.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 ORC6 PF05460.13 KZN90502.1 - 0.031 13.6 0.7 0.03 13.6 0.7 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) zf-C2H2 PF00096.26 KZN90504.1 - 1.6e-07 31.4 12.4 0.00013 22.2 0.4 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type Fungal_trans PF04082.18 KZN90504.1 - 2.3e-06 26.9 0.6 4.5e-06 25.9 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KZN90504.1 - 4.1e-05 23.8 16.1 0.00012 22.4 5.8 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KZN90504.1 - 0.0011 19.2 2.3 0.53 10.6 0.0 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KZN90504.1 - 0.0015 18.5 9.8 0.063 13.3 0.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KZN90504.1 - 0.0027 18.4 16.8 0.0068 17.2 0.3 3.8 5 0 0 5 5 5 2 C2H2-type zinc finger CtnDOT_TraJ PF07863.11 KZN90504.1 - 0.085 13.5 0.4 0.22 12.2 0.4 1.6 1 0 0 1 1 1 0 Homologues of TraJ from Bacteroides conjugative transposon zf-Paramyx-P PF13008.7 KZN90504.1 - 0.35 10.3 1.9 0.71 9.4 1.9 1.5 1 0 0 1 1 1 0 Zinc-binding domain of Paramyxoviridae V protein MFS_1 PF07690.16 KZN90505.1 - 1.6e-38 132.6 27.3 2.1e-38 132.2 27.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN90505.1 - 7.6e-12 44.8 7.4 7.6e-12 44.8 7.4 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KZN90505.1 - 9.7e-06 24.3 4.9 6e-05 21.7 2.6 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Gly-zipper_Omp PF13488.6 KZN90505.1 - 0.078 13.0 2.1 13 5.8 0.3 2.9 2 0 0 2 2 2 0 Glycine zipper Rick_17kDa_Anti PF05433.15 KZN90505.1 - 0.12 12.2 1.3 3 7.8 0.1 2.8 2 0 0 2 2 2 0 Glycine zipper 2TM domain FAA_hydrolase PF01557.18 KZN90506.1 - 4.3e-57 193.3 0.0 5.8e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family B12-binding PF02310.19 KZN90507.1 - 4.5e-05 23.5 0.1 6.5e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 B12 binding domain FtsK_SpoIIIE PF01580.18 KZN90507.1 - 0.0081 15.5 0.0 0.0086 15.4 0.0 1.1 1 0 0 1 1 1 1 FtsK/SpoIIIE family REF PF05755.12 KZN90507.1 - 0.035 13.9 0.1 0.039 13.8 0.1 1.1 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) EHN PF06441.12 KZN90509.1 - 6.9e-36 122.9 1.5 7.8e-35 119.5 0.1 2.3 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KZN90509.1 - 1.1e-09 38.3 0.0 2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KZN90509.1 - 5.6e-05 23.8 1.3 9.6e-05 23.1 1.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KZN90510.1 - 1.9e-27 96.5 0.0 2.2e-22 79.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KZN90510.1 - 3.4e-13 49.4 0.0 6e-13 48.6 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KZN90510.1 - 7e-13 49.7 0.0 1.1e-12 49.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KZN90510.1 - 6.4e-08 32.6 0.1 4.2e-06 26.7 0.1 2.2 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 KZN90510.1 - 9e-08 32.5 0.0 1.3e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.13 KZN90510.1 - 6.5e-06 26.2 0.0 8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KZN90510.1 - 0.00066 18.7 0.0 0.0016 17.4 0.0 1.5 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KZN90510.1 - 0.00087 18.4 0.0 0.0017 17.4 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase Esterase PF00756.20 KZN90510.1 - 0.001 18.8 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.14 KZN90510.1 - 0.0023 16.7 0.0 0.0051 15.6 0.0 1.6 1 0 0 1 1 1 1 Ndr family Ser_hydrolase PF06821.13 KZN90510.1 - 0.0063 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase LIDHydrolase PF10230.9 KZN90510.1 - 0.0068 16.0 0.0 0.014 14.9 0.0 1.6 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 KZN90510.1 - 0.0073 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Palm_thioest PF02089.15 KZN90510.1 - 0.008 16.0 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF3530 PF12048.8 KZN90510.1 - 0.021 14.2 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Abhydrolase_5 PF12695.7 KZN90510.1 - 0.044 13.6 0.0 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF2974 PF11187.8 KZN90510.1 - 0.069 12.7 0.0 0.13 11.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) DUF1664 PF07889.12 KZN90511.1 - 7.5e-06 26.0 46.1 0.0051 16.8 3.6 8.4 6 3 3 10 10 10 4 Protein of unknown function (DUF1664) PKcGMP_CC PF16808.5 KZN90511.1 - 0.013 15.4 0.0 0.013 15.4 0.0 4.4 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Filament PF00038.21 KZN90511.1 - 0.024 14.2 54.8 0.019 14.6 18.3 5.5 2 1 3 5 5 5 0 Intermediate filament protein DPM3 PF08285.11 KZN90511.1 - 0.21 11.8 0.1 1.5 9.1 0.0 2.5 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Baculo_PEP_C PF04513.12 KZN90511.1 - 0.24 11.5 57.1 0.047 13.7 0.9 8.4 2 2 5 8 8 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus LppA PF16708.5 KZN90511.1 - 0.25 11.2 3.1 3.3 7.6 1.6 3.4 2 1 1 3 3 3 0 Lipoprotein confined to pathogenic Mycobacterium NPV_P10 PF05531.12 KZN90511.1 - 0.28 11.7 55.6 3.6 8.1 1.3 11.1 7 5 2 9 9 9 0 Nucleopolyhedrovirus P10 protein Osmo_CC PF08946.10 KZN90511.1 - 0.31 11.3 6.9 31 4.9 0.0 5.5 5 0 0 5 5 5 0 Osmosensory transporter coiled coil BLOC1_2 PF10046.9 KZN90511.1 - 4 7.8 46.7 0.78 10.1 0.1 9.6 4 3 5 10 10 10 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 KZN90511.1 - 4.6 7.4 54.8 1.7 8.8 9.0 8.1 3 1 4 9 9 9 0 Fibrinogen alpha/beta chain family ApoO PF09769.9 KZN90511.1 - 7.1 6.6 15.4 16 5.5 0.0 6.3 5 2 2 7 7 7 0 Apolipoprotein O DUF4407 PF14362.6 KZN90511.1 - 7.5 5.8 59.7 0.36 10.1 9.9 6.1 2 1 3 5 5 4 0 Domain of unknown function (DUF4407) TIP49 PF06068.13 KZN90512.1 - 4.6e-153 509.6 3.3 6.3e-153 509.1 3.3 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KZN90512.1 - 3.3e-21 75.2 0.3 1.1e-20 73.5 0.3 2.0 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KZN90512.1 - 3.9e-09 37.0 0.7 8.5e-06 26.2 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KZN90512.1 - 4.4e-08 33.0 0.4 6.9e-05 22.7 0.1 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KZN90512.1 - 1.5e-06 28.7 0.2 5.4e-06 26.9 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.15 KZN90512.1 - 2.5e-06 27.0 0.9 5.3e-06 26.0 0.9 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 KZN90512.1 - 0.0011 18.4 0.8 0.012 15.1 0.5 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KZN90512.1 - 0.0086 15.8 0.0 5.4 6.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.6 KZN90512.1 - 0.014 15.7 2.3 0.23 11.8 2.3 2.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KZN90512.1 - 0.027 14.4 0.2 0.92 9.5 0.0 2.8 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 KZN90512.1 - 0.04 13.7 0.6 0.15 11.8 0.6 2.0 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KZN90512.1 - 0.04 14.2 0.0 0.092 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KZN90512.1 - 0.044 13.4 0.1 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KZN90512.1 - 0.058 12.9 0.2 0.46 10.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 KZN90512.1 - 0.063 12.4 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TFIID-31kDa PF02291.15 KZN90512.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit GYF PF02213.16 KZN90513.1 - 1.6e-12 46.9 2.2 1.6e-12 46.9 2.2 1.9 2 0 0 2 2 2 1 GYF domain UFD1 PF03152.14 KZN90514.1 - 2e-74 248.7 0.0 2.6e-74 248.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 KZN90514.1 - 0.0015 18.3 0.0 0.046 13.5 0.0 2.4 1 1 1 2 2 2 1 Cell division protein 48 (CDC48), domain 2 DUF829 PF05705.14 KZN90515.1 - 5.5e-56 190.2 0.0 6.4e-56 189.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF4246 PF14033.6 KZN90516.1 - 8.3e-136 453.7 0.1 1.1e-135 453.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) RNA_pol_Rpb2_6 PF00562.28 KZN90517.1 - 1.9e-121 405.8 1.0 4.8e-121 404.5 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KZN90517.1 - 1.9e-54 184.3 0.5 2.9e-54 183.7 0.5 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KZN90517.1 - 7.4e-33 112.8 2.2 1.6e-32 111.8 0.3 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KZN90517.1 - 4.6e-29 101.4 3.6 9.1e-29 100.4 3.6 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KZN90517.1 - 2.7e-24 85.2 1.8 4.8e-24 84.4 0.6 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KZN90517.1 - 1.5e-19 69.9 0.4 4.1e-19 68.5 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KZN90517.1 - 1.2e-11 45.0 0.9 3.5e-11 43.5 0.9 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 NRDD PF13597.6 KZN90517.1 - 0.032 13.0 0.2 0.073 11.8 0.1 1.5 2 0 0 2 2 2 0 Anaerobic ribonucleoside-triphosphate reductase PUF PF00806.19 KZN90518.1 - 9.1e-61 198.3 10.8 2.9e-07 29.8 0.1 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 KZN90518.1 - 0.012 16.0 0.4 3.7 7.9 0.0 4.0 1 1 2 4 4 4 0 CPL (NUC119) domain MgtE_N PF03448.17 KZN90518.1 - 0.045 14.3 0.1 0.17 12.5 0.1 1.9 1 0 0 1 1 1 0 MgtE intracellular N domain ORC5_C PF14630.6 KZN90519.1 - 3.4e-86 289.3 0.0 4.3e-86 288.9 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 KZN90519.1 - 4.2e-17 63.0 0.1 1.2e-16 61.6 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 KZN90519.1 - 0.0089 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain Mito_fiss_reg PF05308.11 KZN90520.1 - 0.0058 16.7 1.3 0.0096 16.0 1.3 1.3 1 0 0 1 1 1 1 Mitochondrial fission regulator E1-E2_ATPase PF00122.20 KZN90521.1 - 8.1e-45 152.6 4.7 8.1e-45 152.6 4.7 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KZN90521.1 - 1.1e-16 61.8 0.7 5.1e-16 59.6 0.7 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KZN90521.1 - 3.2e-10 39.5 0.0 1.1e-09 37.8 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KZN90521.1 - 0.016 15.0 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KZN90521.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) 7tm_1 PF00001.21 KZN90523.1 - 1.4e-08 34.4 0.9 2.1e-08 33.8 0.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 KZN90523.1 - 6.2e-08 32.1 5.9 6.2e-08 32.1 5.9 1.4 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.8 KZN90523.1 - 1.1e-07 31.8 11.9 3.5e-07 30.2 11.9 1.8 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_2 PF00002.24 KZN90523.1 - 0.0011 18.3 2.6 0.0017 17.7 2.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7TM_GPCR_Srsx PF10320.9 KZN90523.1 - 0.0018 17.7 5.0 0.0027 17.1 5.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Tmemb_185A PF10269.9 KZN90523.1 - 0.0029 17.3 0.6 0.0045 16.7 0.6 1.2 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein FixQ PF05545.11 KZN90523.1 - 0.84 9.7 0.1 0.84 9.7 0.1 2.9 2 1 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Frizzled PF01534.17 KZN90523.1 - 0.88 8.5 12.3 0.68 8.9 4.0 3.0 2 1 1 3 3 3 0 Frizzled/Smoothened family membrane region CFEM PF05730.11 KZN90524.1 - 0.00054 20.0 8.0 0.00098 19.2 8.0 1.5 1 1 0 1 1 1 1 CFEM domain EF-hand_4 PF12763.7 KZN90525.1 - 5e-36 122.8 0.0 4.7e-14 52.2 0.0 4.0 4 0 0 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 KZN90525.1 - 4.6e-07 30.2 0.0 0.0011 19.4 0.0 4.1 3 1 1 4 4 4 1 EF-hand domain pair UBA PF00627.31 KZN90525.1 - 2.7e-06 27.2 0.0 6e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.32 KZN90525.1 - 5.8e-06 25.5 0.0 0.0023 17.3 0.0 4.4 5 0 0 5 5 5 1 EF hand GAS PF13851.6 KZN90525.1 - 0.00015 21.2 24.1 0.0039 16.6 11.8 2.2 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding EF-hand_8 PF13833.6 KZN90525.1 - 0.00034 20.4 0.0 0.19 11.6 0.0 4.0 4 0 0 4 4 4 1 EF-hand domain pair Spc7 PF08317.11 KZN90525.1 - 0.0006 18.8 29.1 0.027 13.4 14.8 2.2 1 1 1 2 2 2 2 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KZN90525.1 - 0.00086 19.4 30.9 0.032 14.3 17.6 2.4 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein EF-hand_6 PF13405.6 KZN90525.1 - 0.0016 18.2 2.5 1.1 9.3 0.0 5.1 6 0 0 6 6 5 1 EF-hand domain Macoilin PF09726.9 KZN90525.1 - 0.0019 16.9 7.7 0.0019 16.9 7.7 1.7 2 0 0 2 2 2 1 Macoilin family DUF3584 PF12128.8 KZN90525.1 - 0.074 10.6 25.0 0.1 10.1 25.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) EF-hand_5 PF13202.6 KZN90525.1 - 0.11 12.1 0.1 0.61 9.7 0.1 2.3 2 0 0 2 2 2 0 EF hand TMF_TATA_bd PF12325.8 KZN90525.1 - 0.11 12.8 23.5 0.52 10.5 4.1 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding FPP PF05911.11 KZN90525.1 - 0.49 8.5 20.1 0.73 8.0 20.1 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF3450 PF11932.8 KZN90525.1 - 0.65 9.3 27.5 0.018 14.4 15.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FUSC PF04632.12 KZN90525.1 - 1.1 7.7 8.5 1.6 7.2 8.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4686 PF15742.5 KZN90525.1 - 1.3 8.0 27.5 2.1 7.4 27.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) DUF4201 PF13870.6 KZN90525.1 - 3.1 7.5 22.1 0.56 9.9 2.4 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) Fib_alpha PF08702.10 KZN90525.1 - 3.9 7.6 18.9 0.95 9.6 9.9 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 KZN90525.1 - 4.4 6.8 16.9 7.6 6.0 16.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit COG2 PF06148.11 KZN90525.1 - 5.3 7.1 10.9 15 5.7 3.5 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF724 PF05266.14 KZN90525.1 - 5.5 6.8 20.7 8.3 6.2 8.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Fez1 PF06818.15 KZN90525.1 - 6.2 7.2 24.9 1.4 9.3 14.0 2.4 1 1 1 2 2 2 0 Fez1 Tubulin PF00091.25 KZN90526.1 - 1.8e-66 224.1 0.0 2.7e-66 223.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KZN90526.1 - 4.7e-50 169.0 0.0 8.6e-50 168.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KZN90526.1 - 0.0012 18.6 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Pga1 PF10333.9 KZN90527.1 - 0.001 19.0 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 GPI-Mannosyltransferase II co-activator tRNA-synt_2 PF00152.20 KZN90528.1 - 3.1e-72 243.3 0.0 4.6e-72 242.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 KZN90528.1 - 1.4e-15 57.1 0.0 2e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 KZN90528.1 - 0.0018 18.2 0.1 0.0037 17.2 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KZN90528.1 - 0.0068 15.9 0.1 4.3 6.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) MCM_N PF14551.6 KZN90528.1 - 0.029 14.9 0.0 0.083 13.5 0.0 1.8 1 0 0 1 1 1 0 MCM N-terminal domain SAGA-Tad1 PF12767.7 KZN90528.1 - 0.047 13.4 0.2 0.097 12.4 0.2 1.5 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Abhydrolase_3 PF07859.13 KZN90529.1 - 7.3e-42 143.6 0.0 9.4e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KZN90529.1 - 4.2e-06 25.9 0.3 2.1e-05 23.6 0.3 1.8 1 1 0 1 1 1 1 Carboxylesterase family DUF2974 PF11187.8 KZN90529.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 KZN90529.1 - 0.12 12.2 0.0 0.59 9.9 0.0 1.9 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KZN90529.1 - 0.13 11.7 0.0 4.3 6.7 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family COesterase PF00135.28 KZN90530.1 - 2.8e-12 46.3 0.0 4.5e-07 29.1 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family SKG6 PF08693.10 KZN90531.1 - 6e-07 28.8 0.7 1.8e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Mid2 PF04478.12 KZN90531.1 - 0.0018 18.1 0.1 0.0049 16.7 0.0 1.7 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor DUF2407_C PF13373.6 KZN90531.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain MIP PF00230.20 KZN90532.1 - 3.7e-46 157.7 10.3 4.6e-46 157.4 10.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein MFS_1 PF07690.16 KZN90533.1 - 4e-37 127.9 42.2 1.4e-36 126.2 35.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN90533.1 - 9.8e-14 51.1 15.2 9.8e-14 51.1 15.2 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KZN90533.1 - 5.2e-06 25.2 6.6 5.2e-06 25.2 6.6 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Glyco_transf_8 PF01501.20 KZN90534.1 - 1.3e-11 44.6 0.2 8.5e-11 41.9 0.2 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Gly_transf_sug PF04488.15 KZN90536.1 - 4.2e-08 33.7 0.0 8.6e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KZN90536.1 - 0.039 13.3 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein RRN3 PF05327.11 KZN90537.1 - 1.5e-174 581.7 0.0 1.9e-174 581.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Fungal_trans PF04082.18 KZN90540.1 - 9.4e-18 64.2 1.1 5.4e-17 61.7 0.2 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain PRK PF00485.18 KZN90541.1 - 1.9e-05 24.5 0.0 0.026 14.3 0.0 2.2 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 KZN90541.1 - 0.00054 19.3 0.0 0.00087 18.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 KZN90541.1 - 0.0013 19.3 0.0 0.0041 17.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 KZN90541.1 - 0.0013 17.7 0.0 0.0022 17.0 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 KZN90541.1 - 0.0021 18.2 0.0 0.0055 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KZN90541.1 - 0.0048 16.6 0.0 0.016 14.9 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain APS_kinase PF01583.20 KZN90541.1 - 0.0098 15.8 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.6 KZN90541.1 - 0.02 15.2 0.0 0.042 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF463 PF04317.12 KZN90541.1 - 0.032 13.2 0.0 0.051 12.5 0.0 1.3 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA_14 PF13173.6 KZN90541.1 - 0.033 14.2 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KZN90541.1 - 0.08 12.8 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain ABC_tran PF00005.27 KZN90541.1 - 0.082 13.4 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter T2SSE PF00437.20 KZN90541.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Torsin PF06309.11 KZN90541.1 - 0.15 12.2 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 Torsin NACHT PF05729.12 KZN90541.1 - 0.15 12.0 0.1 0.32 10.9 0.1 1.5 1 0 0 1 1 1 0 NACHT domain Tyr-DNA_phospho PF06087.12 KZN90542.1 - 7.8e-167 555.5 0.0 9.6e-167 555.2 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Iso_dh PF00180.20 KZN90542.1 - 9.7e-83 278.2 0.0 1.6e-82 277.5 0.0 1.3 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ACBP PF00887.19 KZN90543.1 - 1.8e-12 47.3 0.2 3.3e-12 46.5 0.2 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein MR_MLE_N PF02746.16 KZN90543.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain TRH PF05438.12 KZN90543.1 - 0.2 11.4 0.0 0.24 11.1 0.0 1.1 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) U-box PF04564.15 KZN90544.1 - 6e-20 71.2 0.0 1.1e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 U-box domain TPR_2 PF07719.17 KZN90544.1 - 9.2e-07 28.5 5.2 0.0004 20.3 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KZN90544.1 - 1.4e-05 24.7 5.7 6.5e-05 22.6 0.1 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KZN90544.1 - 3.4e-05 24.3 3.7 0.099 13.5 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KZN90544.1 - 0.0002 21.8 1.8 0.1 13.2 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KZN90544.1 - 0.0015 18.8 1.5 0.25 11.7 1.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 KZN90544.1 - 0.0017 19.1 0.3 0.0034 18.1 0.3 1.5 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_11 PF13414.6 KZN90544.1 - 0.011 15.4 0.1 0.038 13.7 0.0 2.1 2 0 0 2 2 2 0 TPR repeat TPR_16 PF13432.6 KZN90544.1 - 0.019 15.6 10.8 1 10.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KZN90544.1 - 0.02 15.3 0.2 2.8 8.5 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KZN90544.1 - 0.078 13.2 0.6 2 8.7 0.7 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Phasin_2 PF09361.10 KZN90544.1 - 0.88 9.9 7.4 0.75 10.1 4.8 2.2 2 0 0 2 2 2 0 Phasin protein LacAB_rpiB PF02502.18 KZN90545.1 - 1.7e-43 148.0 0.0 1.9e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase URO-D PF01208.17 KZN90545.1 - 0.038 13.1 0.0 0.076 12.2 0.0 1.4 2 0 0 2 2 2 0 Uroporphyrinogen decarboxylase (URO-D) TIM PF00121.18 KZN90546.1 - 5.9e-41 140.4 0.0 7.4e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase DHO_dh PF01180.21 KZN90547.1 - 2.2e-67 227.3 0.0 5.6e-55 186.6 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase FMN_dh PF01070.18 KZN90547.1 - 6e-05 22.2 0.1 0.0046 16.0 0.3 2.4 2 1 0 2 2 2 2 FMN-dependent dehydrogenase PcrB PF01884.17 KZN90547.1 - 0.014 14.8 0.2 1.7 8.0 0.0 2.3 2 0 0 2 2 2 0 PcrB family ADH_zinc_N PF00107.26 KZN90548.1 - 9.8e-25 87.0 0.3 1.6e-24 86.3 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KZN90548.1 - 1.8e-22 79.2 1.0 3e-22 78.6 1.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KZN90548.1 - 3.5e-14 54.0 0.0 6.5e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glucokinase PF02685.16 KZN90548.1 - 0.085 11.8 0.2 0.14 11.1 0.2 1.3 1 0 0 1 1 1 0 Glucokinase Arf PF00025.21 KZN90549.1 - 1.7e-73 245.8 0.1 2e-73 245.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KZN90549.1 - 4.9e-14 52.6 0.0 6.6e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KZN90549.1 - 3.7e-12 46.1 0.0 4.7e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KZN90549.1 - 7.1e-11 42.0 0.0 8.5e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KZN90549.1 - 1.6e-09 37.4 0.1 2.4e-05 23.7 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KZN90549.1 - 2.3e-08 33.7 0.0 3e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KZN90549.1 - 3.4e-06 27.1 0.0 6.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KZN90549.1 - 0.00044 19.8 0.0 0.035 13.6 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KZN90549.1 - 0.0086 15.6 0.7 0.037 13.5 0.7 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Actin PF00022.19 KZN90550.1 - 1.1e-30 106.6 0.0 3.5e-18 65.4 0.0 2.4 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 KZN90550.1 - 3e-05 23.0 0.0 0.0024 16.8 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Actin_micro PF17003.5 KZN90550.1 - 0.00072 18.8 0.5 0.0016 17.7 0.1 1.7 2 0 0 2 2 2 1 Putative actin-like family FtsA PF14450.6 KZN90550.1 - 0.004 17.6 0.0 0.014 15.8 0.0 2.0 2 1 0 2 2 2 1 Cell division protein FtsA DUF2114 PF09887.9 KZN90550.1 - 0.13 10.8 0.1 0.17 10.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) Paf1 PF03985.13 KZN90551.1 - 1.1e-54 186.0 0.0 1.6e-54 185.5 0.0 1.2 1 0 0 1 1 1 1 Paf1 APH PF01636.23 KZN90552.1 - 3.8e-18 66.3 0.0 5.7e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KZN90552.1 - 0.0026 17.2 0.0 0.051 12.9 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Choline_kinase PF01633.20 KZN90552.1 - 0.076 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 KZN90553.1 - 1.2e-12 48.3 0.0 2.3e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KZN90553.1 - 0.029 13.2 0.0 0.69 8.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) DUF3419 PF11899.8 KZN90554.1 - 5.2e-159 529.6 0.0 7e-159 529.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 KZN90554.1 - 2.2e-12 47.1 0.0 3.1e-10 40.1 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN90554.1 - 5.8e-10 39.2 0.0 1.3e-08 34.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN90554.1 - 6.4e-10 39.7 0.0 2.8e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN90554.1 - 2.2e-09 37.9 0.0 3e-08 34.3 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN90554.1 - 1.2e-07 32.3 0.0 3.1e-06 27.7 0.0 3.1 3 1 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 KZN90554.1 - 1.6e-06 27.7 0.0 3.5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KZN90554.1 - 0.00039 20.2 0.0 0.00087 19.1 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 KZN90554.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 KZN90554.1 - 0.041 12.9 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.18 KZN90554.1 - 0.099 11.9 0.0 0.26 10.5 0.0 1.6 2 0 0 2 2 2 0 O-methyltransferase domain Ctr PF04145.15 KZN90556.1 - 4.6e-38 131.2 0.1 6.6e-38 130.6 0.1 1.2 1 0 0 1 1 1 1 Ctr copper transporter family Rer1 PF03248.13 KZN90557.1 - 5.3e-81 270.4 3.5 6.1e-81 270.2 3.5 1.0 1 0 0 1 1 1 1 Rer1 family DUF962 PF06127.11 KZN90557.1 - 0.31 11.1 4.8 2.4 8.3 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF962) ECH_1 PF00378.20 KZN90558.1 - 1.2e-80 270.5 0.0 1.9e-80 269.8 0.0 1.3 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KZN90558.1 - 8.2e-37 127.4 0.1 1.8e-32 113.1 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Sugar_tr PF00083.24 KZN90559.1 - 2.5e-85 287.0 19.0 3e-85 286.8 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN90559.1 - 2.1e-16 59.8 24.7 4.8e-14 52.1 17.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KZN90559.1 - 0.00022 20.2 2.6 0.00022 20.2 2.6 2.2 2 0 0 2 2 2 1 MFS_1 like family Catalase PF00199.19 KZN90561.1 - 4.5e-195 648.1 0.5 5.4e-195 647.9 0.5 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KZN90561.1 - 4e-10 39.8 0.0 1.1e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive SOXp PF12336.8 KZN90561.1 - 0.091 13.8 2.0 0.44 11.7 0.2 2.4 2 0 0 2 2 2 0 SOX transcription factor Lipase_3 PF01764.25 KZN90562.1 - 1.8e-06 27.9 0.0 9.5e-06 25.5 0.0 2.2 2 0 0 2 2 2 1 Lipase (class 3) Read-through PF16814.5 KZN90562.1 - 0.037 13.8 0.3 5.9 6.6 0.0 2.7 1 1 1 2 2 2 0 Read-through domain Hydrolase_4 PF12146.8 KZN90562.1 - 0.1 11.9 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PepSY_2 PF13670.6 KZN90562.1 - 0.2 11.7 1.1 4.8 7.3 0.0 2.9 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain Abhydrolase_5 PF12695.7 KZN90562.1 - 0.22 11.2 0.0 0.42 10.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family VPS9 PF02204.18 KZN90563.1 - 1.4e-27 96.0 0.1 2.6e-27 95.1 0.1 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain ECM11 PF15463.6 KZN90564.1 - 8.4e-44 149.4 1.5 4.8e-43 146.9 0.0 2.8 3 0 0 3 3 3 1 Extracellular mutant protein 11 APH PF01636.23 KZN90565.1 - 9.2e-17 61.8 0.0 2.3e-16 60.5 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family RNA_pol_I_TF PF04090.12 KZN90566.1 - 1.9e-11 43.9 0.0 2.5e-10 40.2 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor zf-RING_2 PF13639.6 KZN90567.1 - 1e-13 51.3 4.6 1.6e-13 50.8 4.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KZN90567.1 - 2.9e-11 43.5 2.5 5.9e-11 42.5 2.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KZN90567.1 - 1.3e-09 37.8 3.7 2e-09 37.1 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KZN90567.1 - 7.7e-08 32.1 3.5 1.2e-07 31.5 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KZN90567.1 - 1.2e-07 31.3 2.4 2.3e-07 30.5 2.4 1.4 1 0 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 KZN90567.1 - 3.3e-06 26.6 2.1 5.8e-06 25.8 2.1 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KZN90567.1 - 3.8e-06 26.9 0.4 7.3e-06 26.0 0.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KZN90567.1 - 2.1e-05 24.3 2.6 3.4e-05 23.6 2.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KZN90567.1 - 3.8e-05 23.5 2.7 5.8e-05 23.0 2.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KZN90567.1 - 0.00013 21.9 3.8 0.00026 20.9 3.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KZN90567.1 - 0.00035 20.4 1.6 0.00056 19.7 1.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 KZN90567.1 - 0.0046 17.1 5.0 0.0071 16.5 5.0 1.3 1 0 0 1 1 1 1 RING-variant domain zf-Nse PF11789.8 KZN90567.1 - 0.0083 15.9 1.0 0.017 14.9 1.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 KZN90567.1 - 0.028 14.7 1.5 0.052 13.9 1.5 1.4 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 KZN90567.1 - 0.05 13.8 2.9 0.09 13.0 2.9 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 KZN90567.1 - 0.1 12.7 1.8 0.19 11.8 1.8 1.4 1 0 0 1 1 1 0 Zinc-finger zf-C3HC4_5 PF17121.5 KZN90567.1 - 0.13 12.2 0.9 0.26 11.2 0.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_9 PF13901.6 KZN90567.1 - 0.19 11.7 0.2 0.3 11.1 0.2 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-RING_6 PF14835.6 KZN90567.1 - 0.2 11.5 1.5 0.39 10.6 1.5 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KZN90567.1 - 0.22 11.3 3.3 0.36 10.6 3.3 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 KZN90567.1 - 2.5 8.1 4.1 4 7.4 4.1 1.4 1 0 0 1 1 1 0 PHD-finger Formyl_trans_N PF00551.19 KZN90568.1 - 2e-40 138.4 0.1 2.4e-40 138.2 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase Fungal_trans_2 PF11951.8 KZN90569.1 - 1.8e-11 43.5 0.6 3.3e-11 42.6 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN90569.1 - 4.6e-07 29.8 8.5 7.7e-07 29.1 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GvpG PF05120.12 KZN90569.1 - 0.052 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Gas vesicle protein G DEAD PF00270.29 KZN90570.1 - 6.4e-26 91.2 0.0 1.1e-25 90.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 KZN90570.1 - 9.1e-19 68.0 0.1 2.5e-18 66.6 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 KZN90570.1 - 1.1e-12 48.3 0.1 3.6e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CDT1 PF08839.11 KZN90570.1 - 8.9e-08 32.6 0.0 1.6e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor CDT1 like ResIII PF04851.15 KZN90570.1 - 7.4e-05 22.8 0.0 0.00013 22.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Peptidase_S10 PF00450.22 KZN90571.1 - 8.4e-90 302.2 1.1 1.1e-89 301.8 1.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Ran_BP1 PF00638.18 KZN90572.1 - 6.7e-18 65.1 0.1 1e-17 64.5 0.1 1.3 1 0 0 1 1 1 1 RanBP1 domain Casein_kappa PF00997.18 KZN90572.1 - 0.39 10.8 5.0 1 9.5 5.0 1.7 1 0 0 1 1 1 0 Kappa casein Yip1 PF04893.17 KZN90573.1 - 2.1e-12 47.1 15.0 3.4e-12 46.4 15.0 1.4 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 KZN90573.1 - 0.073 12.8 6.6 0.12 12.2 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) DUF2070 PF09843.9 KZN90573.1 - 6 5.0 11.3 7.2 4.8 11.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Bac_luciferase PF00296.20 KZN90574.1 - 1.3e-60 205.4 0.1 1.8e-60 205.0 0.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase PPR_2 PF13041.6 KZN90575.1 - 1.3e-23 82.9 0.0 2.9e-16 59.4 0.0 3.3 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.6 KZN90575.1 - 1.7e-10 40.8 0.0 0.00021 21.3 0.0 3.2 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR PF01535.20 KZN90575.1 - 4.6e-05 23.4 0.0 0.11 12.8 0.0 3.9 3 0 0 3 3 3 1 PPR repeat PPR_long PF17177.4 KZN90575.1 - 0.013 14.9 0.0 0.013 14.9 0.0 1.8 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KZN90575.1 - 0.1 12.3 1.2 16 5.3 0.0 3.6 4 0 0 4 4 4 0 PPR repeat DUF1387 PF07139.11 KZN90576.1 - 0.085 12.6 0.1 0.085 12.6 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) DUF3987 PF13148.6 KZN90576.1 - 7.3 5.5 6.9 12 4.8 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Lipase_GDSL PF00657.22 KZN90577.1 - 9.6e-07 29.0 0.1 1.2e-06 28.7 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KZN90577.1 - 0.00078 19.9 2.2 0.0074 16.7 2.2 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DEAD PF00270.29 KZN90578.1 - 1.9e-49 167.8 0.0 2.1e-48 164.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KZN90578.1 - 2.1e-30 105.3 0.0 6.6e-30 103.7 0.0 1.9 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KZN90578.1 - 0.00072 19.6 0.0 0.0024 17.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KZN90578.1 - 0.012 14.8 0.2 0.019 14.2 0.2 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF5335 PF17269.2 KZN90578.1 - 0.02 14.7 0.1 0.037 13.9 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5335) AAA_19 PF13245.6 KZN90578.1 - 0.034 14.5 0.0 2.3 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain UTP25 PF06862.12 KZN90578.1 - 0.042 12.6 0.1 2.4 6.8 0.0 2.1 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 SBP_bac_8 PF13416.6 KZN90578.1 - 0.084 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein DUF2443 PF10398.9 KZN90578.1 - 0.16 12.0 0.1 0.46 10.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) DUF445 PF04286.12 KZN90578.1 - 0.17 11.6 0.1 0.27 11.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) AAA_22 PF13401.6 KZN90578.1 - 0.34 11.2 2.5 22 5.3 0.0 3.4 3 1 1 4 4 4 0 AAA domain Phos_pyr_kin PF08543.12 KZN90579.1 - 8.1e-82 274.3 0.4 1.1e-81 273.8 0.4 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 KZN90579.1 - 9.1e-51 172.7 0.4 1.2e-50 172.2 0.4 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 KZN90579.1 - 9.9e-06 25.1 0.2 0.00015 21.2 0.2 2.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 KZN90579.1 - 5.2e-05 22.8 1.5 0.00013 21.6 0.4 2.0 2 0 0 2 2 2 1 Carbohydrate kinase HK PF02110.15 KZN90579.1 - 0.0023 17.4 0.7 0.09 12.2 0.1 2.2 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family DNA_pol_B PF00136.21 KZN90580.1 - 2.7e-118 395.6 1.3 3.7e-118 395.2 1.3 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 KZN90580.1 - 2.7e-69 232.6 1.3 5.9e-69 231.5 1.3 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 KZN90580.1 - 4.4e-44 151.0 0.0 1e-43 149.8 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 KZN90580.1 - 1.2e-23 83.0 11.8 1.7e-23 82.5 7.0 3.1 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal NCKAP5 PF15246.6 KZN90580.1 - 0.019 14.6 0.7 0.043 13.4 0.7 1.5 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein Ribosomal_S9 PF00380.19 KZN90581.1 - 3.9e-33 114.5 0.8 4.4e-33 114.4 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 PilJ PF13675.6 KZN90581.1 - 0.049 13.7 0.2 0.073 13.1 0.2 1.2 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Ribosomal_L13 PF00572.18 KZN90582.1 - 4.3e-43 146.5 0.0 5.9e-43 146.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 Uricase PF01014.18 KZN90583.1 - 1e-77 258.7 0.7 1.3e-41 141.9 0.4 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.19 KZN90583.1 - 0.0086 15.9 0.3 0.023 14.5 0.0 1.8 2 0 0 2 2 2 1 Plasmid recombination enzyme SnoaL_2 PF12680.7 KZN90583.1 - 0.024 15.3 0.2 0.059 14.0 0.2 1.6 1 0 0 1 1 1 0 SnoaL-like domain MFS_1 PF07690.16 KZN90584.1 - 5.9e-42 143.9 52.7 8.9e-36 123.5 29.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KZN90584.1 - 0.14 10.4 9.7 0.061 11.6 1.6 3.1 2 2 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Ac76 PF05814.11 KZN90584.1 - 0.2 11.7 0.6 0.83 9.7 0.2 2.3 2 0 0 2 2 2 0 Orf76 (Ac76) MFS_3 PF05977.13 KZN90584.1 - 9 4.6 17.0 0.59 8.5 10.8 2.2 2 1 1 3 3 3 0 Transmembrane secretion effector PAD_porph PF04371.15 KZN90585.1 - 4.1e-95 318.7 0.0 5.1e-95 318.4 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase SelP_N PF04592.14 KZN90586.1 - 0.02 14.3 17.8 0.03 13.7 17.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Presenilin PF01080.17 KZN90586.1 - 0.41 9.3 1.8 0.4 9.4 1.8 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 KZN90586.1 - 0.58 9.3 6.7 0.64 9.2 6.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CCDC106 PF15794.5 KZN90586.1 - 2 8.1 4.7 3 7.5 4.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF4551 PF15087.6 KZN90586.1 - 4 6.2 8.2 4.8 5.9 8.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Macoilin PF09726.9 KZN90586.1 - 5.9 5.3 9.1 6.8 5.1 9.1 1.0 1 0 0 1 1 1 0 Macoilin family PAT1 PF09770.9 KZN90586.1 - 6.8 4.8 8.3 8 4.6 8.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-H2C2_2 PF13465.6 KZN90587.1 - 4.7e-06 26.8 12.1 1.5e-05 25.2 1.4 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.12 KZN90587.1 - 0.00016 21.9 4.3 0.00029 21.1 4.3 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KZN90587.1 - 0.00024 21.7 15.0 0.017 15.9 5.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KZN90587.1 - 0.0019 18.4 4.8 0.078 13.3 1.2 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KZN90587.1 - 0.033 14.6 14.5 0.11 13.0 7.1 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.7 KZN90587.1 - 0.75 10.3 5.0 4.2 7.9 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type AA_permease_2 PF13520.6 KZN90588.1 - 1e-67 228.9 44.8 1.2e-67 228.6 44.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN90588.1 - 7e-16 57.9 34.3 9.6e-16 57.4 34.3 1.2 1 0 0 1 1 1 1 Amino acid permease QCR10 PF09796.9 KZN90589.1 - 1.2e-23 82.9 0.0 1.6e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Thioredoxin PF00085.20 KZN90590.1 - 1.5e-38 130.9 0.0 8.6e-24 83.5 0.0 4.2 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KZN90590.1 - 1.4e-11 44.7 0.0 1.3e-05 25.2 0.0 4.3 3 1 1 4 4 4 2 Thioredoxin-like domain AhpC-TSA PF00578.21 KZN90590.1 - 0.00025 21.0 0.4 1.2 9.0 0.0 3.2 4 0 0 4 4 4 2 AhpC/TSA family Thioredoxin_8 PF13905.6 KZN90590.1 - 0.00092 19.5 0.0 1.1 9.6 0.0 3.6 3 0 0 3 3 3 1 Thioredoxin-like HyaE PF07449.11 KZN90590.1 - 0.001 19.0 0.0 0.24 11.4 0.0 2.7 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE TraF PF13728.6 KZN90590.1 - 0.039 13.8 0.0 20 4.9 0.0 3.6 4 0 0 4 4 4 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 KZN90590.1 - 0.071 13.2 0.1 2.2 8.4 0.0 2.7 2 0 0 2 2 2 0 Thioredoxin domain OST3_OST6 PF04756.13 KZN90590.1 - 0.17 11.2 0.0 4.2 6.6 0.0 2.5 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KZN90590.1 - 0.18 12.0 0.3 2.2 8.5 0.1 2.8 3 0 0 3 3 3 0 Thioredoxin-like zinc_ribbon_9 PF14369.6 KZN90590.1 - 3.5 8.0 5.4 44 4.5 1.8 2.6 2 0 0 2 2 2 0 zinc-ribbon ETC_C1_NDUFA5 PF04716.14 KZN90591.1 - 1.6e-27 95.1 2.3 7.1e-26 89.8 0.0 2.8 3 0 0 3 3 3 2 ETC complex I subunit conserved region Ku_PK_bind PF08785.11 KZN90591.1 - 0.031 14.4 0.0 0.073 13.2 0.0 1.6 1 0 0 1 1 1 0 Ku C terminal domain like Coatomer_WDAD PF04053.14 KZN90592.1 - 6.1e-168 559.5 0.0 2.4e-167 557.5 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 KZN90592.1 - 2.1e-38 129.6 6.2 1.8e-06 28.5 0.0 8.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN90592.1 - 3e-07 30.6 0.0 2.8 8.3 0.0 6.0 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KZN90592.1 - 0.00013 20.8 1.6 0.17 10.5 0.0 3.6 1 1 2 3 3 3 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KZN90592.1 - 0.042 13.9 0.0 9.9 6.3 0.0 3.9 1 1 3 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Pkinase PF00069.25 KZN90593.1 - 4.5e-70 236.0 0.0 6.1e-70 235.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN90593.1 - 5.1e-32 111.2 0.0 7e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KZN90593.1 - 1.8e-09 38.1 1.4 3.2e-09 37.3 0.1 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KZN90593.1 - 2.6e-06 26.6 0.0 4e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KZN90593.1 - 0.039 13.3 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like ZZ PF00569.17 KZN90594.1 - 1.6e-10 40.6 4.6 2.6e-10 39.9 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 KZN90594.1 - 2.2e-10 40.6 0.0 5.6e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 KZN90594.1 - 8.2e-08 32.5 0.1 2.6e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 SWIRM domain Phage_Mu_Gam PF07352.12 KZN90594.1 - 5.1 7.0 7.3 13 5.6 0.1 2.9 2 1 1 3 3 3 0 Bacteriophage Mu Gam like protein ECH_1 PF00378.20 KZN90595.1 - 1.3e-53 181.9 0.0 2.1e-53 181.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KZN90595.1 - 1.2e-23 84.1 0.0 1.9e-22 80.2 0.1 2.0 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase DoxD PF04173.13 KZN90595.1 - 0.12 12.3 0.1 0.25 11.3 0.1 1.4 2 0 0 2 2 2 0 TQO small subunit DoxD Mannitol_dh_C PF08125.13 KZN90596.1 - 2.7e-42 144.9 0.0 4.6e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KZN90596.1 - 3.5e-18 66.2 1.1 4.7e-18 65.8 0.2 1.6 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.18 KZN90596.1 - 0.01 15.7 0.1 0.024 14.5 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KZN90596.1 - 0.047 12.9 0.3 0.082 12.1 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SUR7 PF06687.12 KZN90597.1 - 1.4e-19 70.6 4.9 1.8e-19 70.2 4.9 1.0 1 0 0 1 1 1 1 SUR7/PalI family CytochromB561_N PF09786.9 KZN90597.1 - 0.17 10.9 0.6 0.23 10.4 0.6 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Fig1 PF12351.8 KZN90597.1 - 0.51 10.2 11.1 0.37 10.7 7.7 2.3 2 1 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 APH PF01636.23 KZN90598.1 - 3.5e-13 50.0 0.0 4.8e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KZN90598.1 - 0.021 13.7 0.0 4.3 6.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 KZN90598.1 - 0.023 14.3 0.0 0.07 12.7 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase LOH1CR12 PF10158.9 KZN90598.1 - 0.068 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Tumour suppressor protein Sugar_tr PF00083.24 KZN90599.1 - 1.9e-25 89.6 21.6 3.1e-14 52.7 6.9 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter RCC1 PF00415.18 KZN90600.1 - 3.8e-37 126.7 14.4 7.6e-09 36.1 0.1 7.1 7 2 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KZN90600.1 - 1.9e-19 68.9 22.1 8.5e-07 28.6 0.4 7.0 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Rad9 PF04139.13 KZN90601.1 - 1.9e-50 171.7 1.2 2.3e-50 171.4 1.2 1.0 1 0 0 1 1 1 1 Rad9 DUF2218 PF09981.9 KZN90601.1 - 0.16 12.3 0.4 0.76 10.2 0.0 2.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2218) Glyco_transf_54 PF04666.13 KZN90602.1 - 3e-13 49.3 0.0 5.2e-10 38.7 0.0 3.0 2 1 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF2975 PF11188.8 KZN90602.1 - 0.0049 16.7 2.1 0.01 15.8 2.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2975) DUF3405 PF11885.8 KZN90603.1 - 6.2e-152 506.8 11.6 1.4e-151 505.6 11.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) Glyco_transf_54 PF04666.13 KZN90604.1 - 1.7e-08 33.7 0.1 4.2e-06 25.8 0.0 2.9 2 1 0 2 2 2 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Glyco_transf_25 PF01755.17 KZN90604.1 - 0.047 13.6 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Nuc_sug_transp PF04142.15 KZN90604.1 - 0.075 12.2 0.4 0.12 11.5 0.4 1.2 1 0 0 1 1 1 0 Nucleotide-sugar transporter LON_substr_bdg PF02190.16 KZN90605.1 - 2.9e-26 92.6 0.0 4e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KZN90605.1 - 2.1e-13 49.9 16.6 1.9e-11 43.6 10.4 2.9 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KZN90605.1 - 7.2e-11 41.8 15.2 6.7e-09 35.5 6.6 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KZN90605.1 - 9e-11 41.6 20.0 1.2e-07 31.7 4.2 3.5 3 0 0 3 3 3 2 RING-type zinc-finger zf-RING_5 PF14634.6 KZN90605.1 - 9.2e-11 41.5 16.3 5.8e-07 29.4 7.6 2.4 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.6 KZN90605.1 - 2.6e-10 40.4 16.0 1e-07 32.2 8.9 2.6 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_4 PF15227.6 KZN90605.1 - 3.1e-10 40.1 15.2 1.3e-06 28.5 6.3 2.9 2 1 1 3 3 3 2 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KZN90605.1 - 1.2e-09 37.8 15.3 3.1e-07 30.1 8.8 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KZN90605.1 - 4.6e-07 29.6 15.2 6.4e-06 25.9 7.0 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KZN90605.1 - 0.00034 20.4 7.8 0.0053 16.5 5.2 2.7 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 KZN90605.1 - 0.00078 19.5 5.7 0.00078 19.5 5.7 2.4 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KZN90605.1 - 0.00084 19.6 4.3 0.0028 17.9 4.3 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain U-box PF04564.15 KZN90605.1 - 0.0029 17.7 0.1 0.01 16.0 0.0 1.9 2 0 0 2 2 1 1 U-box domain zf-ANAPC11 PF12861.7 KZN90605.1 - 0.14 12.3 2.0 1.4 9.1 1.7 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Ribosomal_L40e PF01020.17 KZN90605.1 - 6.2 6.8 7.8 9.3 6.2 2.5 2.6 2 1 0 2 2 2 0 Ribosomal L40e family DAO PF01266.24 KZN90606.1 - 3.9e-41 141.8 0.4 5e-41 141.5 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.26 KZN90606.1 - 7e-12 45.1 0.1 3.1e-11 43.1 0.0 2.1 3 0 0 3 3 1 1 Rieske [2Fe-2S] domain NAD_binding_8 PF13450.6 KZN90606.1 - 6.1e-08 32.8 1.0 1.7e-07 31.3 0.6 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KZN90606.1 - 5.3e-06 25.9 0.1 1.2e-05 24.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KZN90606.1 - 1.3e-05 24.7 1.0 0.0022 17.4 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KZN90606.1 - 1.7e-05 24.1 0.4 3.3e-05 23.2 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KZN90606.1 - 3.5e-05 23.2 0.0 5.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KZN90606.1 - 3.8e-05 23.1 0.1 5.8e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KZN90606.1 - 4.7e-05 22.8 0.1 0.00013 21.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KZN90606.1 - 0.0022 17.1 0.3 0.0093 15.1 0.2 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KZN90606.1 - 0.003 16.7 0.7 0.0061 15.6 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 KZN90606.1 - 0.0069 16.9 0.4 0.015 15.8 0.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KZN90606.1 - 0.0088 15.4 0.3 0.018 14.4 0.0 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 KZN90606.1 - 0.014 15.3 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 KZN90606.1 - 0.029 13.1 0.1 0.045 12.5 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 KZN90606.1 - 0.046 13.7 0.3 0.33 10.9 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Amidohydro_1 PF01979.20 KZN90607.1 - 4.1e-24 85.5 0.0 6e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KZN90607.1 - 1.6e-13 51.0 0.1 2.8e-06 27.1 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family Zn_clus PF00172.18 KZN90608.1 - 6.7e-07 29.3 10.8 1.2e-06 28.5 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RICTOR_N PF14664.6 KZN90609.1 - 4.1e-125 417.6 0.4 4.1e-125 417.6 0.4 1.7 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 KZN90609.1 - 6.1e-38 129.5 0.1 1.6e-35 121.8 0.0 3.3 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 KZN90609.1 - 2.9e-37 126.6 0.7 1.4e-33 114.8 0.3 4.3 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 KZN90609.1 - 1.1e-26 92.9 1.0 7.7e-26 90.1 0.2 2.8 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 KZN90609.1 - 1.3e-13 50.9 4.7 3e-13 49.7 4.7 1.6 1 0 0 1 1 1 1 Hr1 repeat HIF-1a_CTAD PF08778.10 KZN90609.1 - 0.16 11.6 0.0 8.7 6.1 0.0 2.5 2 0 0 2 2 2 0 HIF-1 alpha C terminal transactivation domain Uds1 PF15456.6 KZN90609.1 - 0.23 11.6 3.5 0.52 10.5 3.5 1.6 1 0 0 1 1 1 0 Up-regulated During Septation PDH PF02153.17 KZN90610.1 - 4.3e-11 42.3 0.0 5.8e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 KZN90610.1 - 3.2e-06 27.6 0.0 7e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KZN90610.1 - 5.4e-06 26.7 0.0 1.7e-05 25.0 0.0 1.8 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 KZN90610.1 - 0.00027 20.6 0.0 0.00072 19.2 0.0 1.8 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 KZN90610.1 - 0.0008 18.8 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KZN90610.1 - 0.015 15.2 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 KZN90610.1 - 0.051 13.2 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KZN90610.1 - 0.078 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Ribosomal_S11 PF00411.19 KZN90611.1 - 3.9e-46 156.0 1.0 5e-46 155.6 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 KZN90611.1 - 0.097 12.9 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) AAR2 PF05282.11 KZN90612.1 - 1.6e-98 330.4 0.0 1.9e-98 330.1 0.0 1.1 1 0 0 1 1 1 1 AAR2 protein FlgD_ig PF13860.6 KZN90612.1 - 0.22 11.4 1.2 0.39 10.6 0.2 1.9 2 0 0 2 2 2 0 FlgD Ig-like domain Aminotran_4 PF01063.19 KZN90613.1 - 1.2e-25 90.7 0.0 1.6e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Fungal_trans PF04082.18 KZN90614.1 - 4.5e-17 62.0 0.4 5.9e-17 61.6 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN90614.1 - 1.5e-05 25.0 10.0 3.3e-05 23.9 10.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0147 PF03685.13 KZN90614.1 - 0.074 13.1 0.0 0.47 10.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0147) Paf67 PF10255.9 KZN90615.1 - 5.3e-159 529.6 0.0 6.2e-159 529.3 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 KZN90615.1 - 0.097 12.8 0.0 0.6 10.4 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Adaptin_N PF01602.20 KZN90616.1 - 8.9e-116 387.5 10.1 1.1e-115 387.2 10.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KZN90616.1 - 5.7e-56 189.0 12.5 4.6e-55 186.1 1.2 3.8 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KZN90616.1 - 1.2e-11 44.9 5.7 0.00019 21.7 0.0 5.2 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.22 KZN90616.1 - 1.1e-10 40.8 3.1 0.0031 17.6 0.0 6.1 6 0 0 6 6 6 3 HEAT repeat Atx10homo_assoc PF09759.9 KZN90616.1 - 4.2e-05 23.5 0.2 0.92 9.6 0.0 4.0 3 1 1 4 4 4 2 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 KZN90616.1 - 0.00024 21.5 6.0 18 5.9 0.0 6.8 8 0 0 8 8 8 0 HEAT-like repeat CLASP_N PF12348.8 KZN90616.1 - 0.0017 17.9 3.2 1.6 8.3 0.0 3.6 4 0 0 4 4 4 2 CLASP N terminal DNA_alkylation PF08713.11 KZN90616.1 - 0.044 13.5 0.1 0.37 10.5 0.0 2.4 2 1 1 3 3 3 0 DNA alkylation repair enzyme Arm PF00514.23 KZN90616.1 - 0.06 13.4 2.7 3.3 7.9 0.0 4.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat CBP_BcsO PF17037.5 KZN90616.1 - 0.17 12.0 2.2 0.32 11.1 2.2 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO TIP120 PF08623.10 KZN90616.1 - 0.21 11.4 3.5 14 5.4 0.1 3.2 4 0 0 4 4 4 0 TATA-binding protein interacting (TIP20) DUF1077 PF06417.12 KZN90617.1 - 2e-49 166.5 2.9 2.6e-49 166.1 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Rubella_Capsid PF05750.11 KZN90617.1 - 3.3 7.2 9.6 4.6 6.8 9.6 1.2 1 0 0 1 1 1 0 Rubella capsid protein TMEM171 PF15471.6 KZN90617.1 - 6.3 5.7 7.5 7.8 5.4 6.8 1.5 1 1 0 1 1 1 0 Transmembrane protein family 171 MFS_1 PF07690.16 KZN90618.1 - 5.6e-53 180.1 18.3 5.6e-53 180.1 18.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN90618.1 - 2.4e-11 43.2 11.2 2.4e-11 43.2 11.2 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_5 PF05631.14 KZN90618.1 - 0.00011 21.3 3.1 0.00021 20.4 3.1 1.4 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM TRI12 PF06609.13 KZN90618.1 - 0.00045 18.8 7.3 0.00047 18.7 5.7 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KZN90618.1 - 0.00081 18.4 4.6 0.00081 18.4 4.6 2.1 3 0 0 3 3 3 1 MFS_1 like family Osw5 PF17062.5 KZN90618.1 - 0.02 15.0 0.2 0.13 12.4 0.0 2.5 2 0 0 2 2 2 0 Outer spore wall 5 OATP PF03137.20 KZN90618.1 - 0.033 12.5 9.0 0.88 7.8 3.8 2.6 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 KZN90618.1 - 2.3 6.5 12.7 0.16 10.3 4.5 2.6 3 0 0 3 3 3 0 Transmembrane secretion effector CPP1-like PF11833.8 KZN90618.1 - 2.4 7.8 4.6 6.4 6.4 4.6 1.7 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Aminotran_5 PF00266.19 KZN90619.1 - 4.4e-12 45.7 0.0 1.4e-11 44.0 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KZN90619.1 - 0.0013 17.3 0.0 0.0027 16.3 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 KZN90619.1 - 0.0046 15.7 0.0 0.0084 14.9 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.17 KZN90619.1 - 0.034 13.4 0.1 0.056 12.7 0.1 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Fe-S_biosyn PF01521.20 KZN90620.1 - 3.1e-11 43.4 0.0 9.4e-11 41.9 0.0 1.7 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Pkinase PF00069.25 KZN90621.1 - 1.6e-31 109.7 0.0 1e-30 107.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN90621.1 - 1.5e-09 37.5 0.0 2.6e-08 33.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KZN90621.1 - 0.075 11.8 0.0 3.9 6.1 0.0 2.3 2 0 0 2 2 2 0 Fungal protein kinase Zn_clus PF00172.18 KZN90622.1 - 1.8e-08 34.3 11.1 3.5e-08 33.4 11.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KZN90622.1 - 1.6e-05 23.9 0.2 2.7e-05 23.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peroxidase_2 PF01328.17 KZN90623.1 - 7.8e-45 153.7 0.2 9.3e-45 153.5 0.2 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 TFIID-18kDa PF02269.16 KZN90623.1 - 0.027 14.5 0.0 1.2 9.2 0.0 2.5 3 0 0 3 3 3 0 Transcription initiation factor IID, 18kD subunit CWC25 PF12542.8 KZN90624.1 - 1.5e-21 77.2 0.1 1.5e-21 77.2 0.1 3.7 3 2 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 KZN90624.1 - 1e-14 54.4 10.2 1e-14 54.4 10.2 4.8 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR FAT PF02259.23 KZN90625.1 - 9.2e-135 449.3 0.2 9.2e-135 449.3 0.2 2.2 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KZN90625.1 - 4.4e-70 236.3 0.0 8.5e-70 235.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 KZN90625.1 - 6.1e-65 218.0 4.7 2.5e-60 203.0 1.3 4.5 4 1 1 5 5 5 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 KZN90625.1 - 4.5e-42 142.5 4.6 2.1e-41 140.4 0.1 3.8 3 0 0 3 3 2 1 FKBP12-rapamycin binding domain FATC PF02260.20 KZN90625.1 - 8e-16 57.6 1.0 1.9e-15 56.4 1.0 1.7 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.6 KZN90625.1 - 6.2e-14 52.1 14.0 0.019 15.5 0.0 11.3 12 2 0 12 12 11 2 HEAT-like repeat HEAT_2 PF13646.6 KZN90625.1 - 3.7e-13 49.7 9.1 0.0041 17.5 0.0 8.9 8 1 1 9 9 9 3 HEAT repeats HEAT PF02985.22 KZN90625.1 - 1.2e-09 37.6 23.3 0.0041 17.2 0.0 11.8 14 0 0 14 14 12 2 HEAT repeat Adaptin_N PF01602.20 KZN90625.1 - 1.5e-06 27.1 4.8 0.043 12.4 0.1 5.5 3 2 2 6 6 6 1 Adaptin N terminal region UME PF08064.13 KZN90625.1 - 0.0011 18.9 2.3 6.5 6.7 0.0 6.6 6 1 1 7 7 7 1 UME (NUC010) domain MMS19_C PF12460.8 KZN90625.1 - 0.0019 17.4 5.3 0.12 11.5 0.0 4.1 4 1 0 4 4 4 1 RNAPII transcription regulator C-terminal Tti2 PF10521.9 KZN90625.1 - 0.0025 17.4 0.9 6.9 6.1 0.0 4.9 3 1 2 5 5 5 1 Tti2 family CLASP_N PF12348.8 KZN90625.1 - 0.0035 16.9 1.0 1.4 8.5 0.0 4.7 5 0 0 5 5 5 1 CLASP N terminal Sec7_N PF12783.7 KZN90625.1 - 0.047 13.6 0.1 2.3 8.1 0.0 3.6 4 0 0 4 4 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Dopey_N PF04118.14 KZN90625.1 - 0.11 11.5 0.3 1.3 8.0 0.1 2.7 2 0 0 2 2 2 0 Dopey, N-terminal TPR_14 PF13428.6 KZN90625.1 - 0.37 11.7 6.5 1.2 10.1 0.1 4.8 3 1 1 4 4 3 0 Tetratricopeptide repeat Epimerase PF01370.21 KZN90626.1 - 1.3e-18 67.3 0.0 1.6e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KZN90626.1 - 2.1e-14 53.2 0.0 2.7e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KZN90626.1 - 5e-09 35.7 0.0 5.5e-08 32.3 0.0 2.2 2 1 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KZN90626.1 - 3.6e-08 33.2 0.0 5.8e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KZN90626.1 - 2e-06 27.8 0.0 5.3e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KZN90626.1 - 0.00014 21.1 0.0 0.00019 20.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KZN90626.1 - 0.00014 21.4 0.0 0.00027 20.4 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN90626.1 - 0.0011 18.9 0.0 0.0025 17.8 0.0 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 KZN90626.1 - 0.0039 16.8 0.3 0.013 15.1 0.3 2.0 2 1 0 2 2 2 1 NmrA-like family adh_short_C2 PF13561.6 KZN90626.1 - 0.011 15.3 0.0 0.024 14.2 0.0 1.5 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Sacchrp_dh_NADP PF03435.18 KZN90626.1 - 0.049 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KZN90626.1 - 0.16 12.4 0.0 0.48 10.9 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Mit_ribos_Mrp51 PF11709.8 KZN90627.1 - 5.8e-111 371.6 0.1 6.8e-111 371.4 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Ribosomal_S17e PF00833.18 KZN90628.1 - 8.6e-61 203.3 1.1 1.1e-60 203.0 1.1 1.1 1 0 0 1 1 1 1 Ribosomal S17 RPAP2_Rtr1 PF04181.13 KZN90629.1 - 9.9e-20 70.6 0.0 1.6e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family CDC45 PF02724.14 KZN90630.1 - 5.1 5.3 6.6 8.2 4.6 6.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1749 PF08538.10 KZN90632.1 - 2.2e-98 329.1 0.0 2.6e-98 328.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_1 PF00561.20 KZN90632.1 - 3.9e-05 23.4 0.3 0.00011 21.9 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF900 PF05990.12 KZN90632.1 - 0.0058 16.2 0.0 0.018 14.6 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 KZN90632.1 - 0.017 14.4 0.1 0.045 13.0 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 KZN90632.1 - 0.021 14.6 0.1 0.12 12.1 0.0 2.3 1 1 1 2 2 2 0 PGAP1-like protein Condensation PF00668.20 KZN90633.1 - 4e-74 249.9 0.0 4.4e-38 131.1 0.0 2.5 2 0 0 2 2 2 2 Condensation domain AMP-binding PF00501.28 KZN90633.1 - 8.5e-73 245.3 0.0 3.2e-68 230.3 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 KZN90633.1 - 5.2e-28 97.2 0.3 2.5e-12 47.0 0.1 3.3 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KZN90633.1 - 0.0007 20.5 0.1 1.7 9.7 0.0 2.9 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain DMA PF03474.14 KZN90633.1 - 0.16 11.6 0.0 0.52 10.0 0.0 1.9 1 0 0 1 1 1 0 DMRTA motif ABC_membrane PF00664.23 KZN90634.1 - 3.7e-90 302.3 29.0 8.2e-52 176.5 7.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KZN90634.1 - 2.3e-62 209.5 0.0 7.9e-31 107.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KZN90634.1 - 3.4e-17 62.6 0.4 7.6e-06 25.5 0.0 4.4 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KZN90634.1 - 1.2e-08 34.6 0.3 0.0024 17.6 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KZN90634.1 - 8.8e-08 32.5 0.9 0.13 12.5 0.0 4.2 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KZN90634.1 - 7.6e-07 29.7 2.8 0.011 16.2 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 KZN90634.1 - 1.6e-06 27.9 2.4 0.026 14.2 0.0 3.9 3 1 0 3 3 3 2 AAA domain APS_kinase PF01583.20 KZN90634.1 - 9.3e-06 25.6 0.2 0.0057 16.6 0.1 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase RsgA_GTPase PF03193.16 KZN90634.1 - 1e-05 25.5 0.2 0.038 13.9 0.0 3.0 3 0 0 3 3 2 2 RsgA GTPase DUF87 PF01935.17 KZN90634.1 - 1.4e-05 25.3 0.2 0.031 14.4 0.0 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_23 PF13476.6 KZN90634.1 - 0.00014 22.4 0.4 0.77 10.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KZN90634.1 - 0.00034 21.1 0.8 8.6 6.8 0.2 4.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 KZN90634.1 - 0.00046 19.1 1.8 0.026 13.3 0.0 2.7 3 0 0 3 3 3 1 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 KZN90634.1 - 0.00047 19.5 0.0 0.28 10.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.6 KZN90634.1 - 0.0011 18.5 1.1 1.2 8.7 0.0 4.3 5 0 0 5 5 4 1 AAA domain AAA_5 PF07728.14 KZN90634.1 - 0.0014 18.6 0.0 3.1 7.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KZN90634.1 - 0.0017 18.9 0.0 3.3 8.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KZN90634.1 - 0.0027 17.6 0.2 0.24 11.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 KZN90634.1 - 0.004 17.3 0.2 4 7.6 0.1 2.7 2 0 0 2 2 2 1 AAA domain KdpD PF02702.17 KZN90634.1 - 0.013 15.0 0.0 1.7 8.1 0.0 2.4 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain DUF3987 PF13148.6 KZN90634.1 - 0.016 14.2 0.0 2.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) NB-ARC PF00931.22 KZN90634.1 - 0.018 14.2 0.1 2.8 7.1 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain AAA_7 PF12775.7 KZN90634.1 - 0.022 14.3 0.1 8.2 5.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DEAD PF00270.29 KZN90634.1 - 0.023 14.5 0.2 0.33 10.7 0.1 3.0 3 1 0 3 3 3 0 DEAD/DEAH box helicase SbcCD_C PF13558.6 KZN90634.1 - 0.023 14.9 0.2 8.7 6.7 0.0 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 KZN90634.1 - 0.024 14.7 0.1 5.8 7.0 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 KZN90634.1 - 0.03 14.0 0.0 1.3 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KZN90634.1 - 0.068 12.8 0.7 12 5.4 0.0 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Cad PF03596.13 KZN90634.1 - 0.085 12.7 4.2 0.33 10.8 0.7 2.8 2 0 0 2 2 2 0 Cadmium resistance transporter AAA_17 PF13207.6 KZN90634.1 - 0.12 12.8 0.0 29 5.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KZN90634.1 - 0.2 11.4 0.3 9.7 5.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Acetyltransf_8 PF13523.6 KZN90635.1 - 5.3e-39 133.2 0.3 7.3e-39 132.7 0.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ECH_1 PF00378.20 KZN90636.1 - 2.1e-51 174.7 0.0 2.6e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KZN90636.1 - 5.2e-25 88.7 0.0 5.6e-22 78.7 0.1 2.4 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DoxD PF04173.13 KZN90636.1 - 0.029 14.3 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 TQO small subunit DoxD MFS_1 PF07690.16 KZN90637.1 - 6.3e-20 71.4 52.3 9.7e-20 70.8 46.5 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Aldo_ket_red PF00248.21 KZN90638.1 - 2.2e-44 151.9 0.0 3e-42 144.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family MIOX PF05153.15 KZN90639.1 - 4.3e-125 416.3 2.3 5.8e-125 415.9 2.3 1.2 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 KZN90639.1 - 0.056 13.7 2.5 0.39 10.9 0.1 2.9 2 2 0 2 2 2 0 HD domain NRIP1_repr_1 PF15687.5 KZN90639.1 - 0.29 10.7 2.2 0.42 10.2 2.2 1.2 1 0 0 1 1 1 0 Nuclear receptor-interacting protein 1 repression 1 GFO_IDH_MocA PF01408.22 KZN90640.1 - 7.6e-24 84.8 0.1 1.4e-23 84.0 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KZN90640.1 - 7.8e-06 25.9 0.0 1.5e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain KRE1 PF17056.5 KZN90640.1 - 0.052 13.3 0.0 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Killer toxin-resistance protein 1 NAD_binding_3 PF03447.16 KZN90640.1 - 0.11 13.1 0.1 0.2 12.3 0.1 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KZN90640.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Peptidase_C13 PF01650.18 KZN90642.1 - 3e-08 33.5 0.0 4.5e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family Glyco_hydro_28 PF00295.17 KZN90643.1 - 8.9e-125 416.1 18.0 1e-124 415.9 18.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 NAD_binding_10 PF13460.6 KZN90644.1 - 1.5e-22 80.4 0.0 2.5e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KZN90644.1 - 8.8e-07 28.6 0.0 1.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KZN90644.1 - 0.014 14.5 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain AMP-binding PF00501.28 KZN90645.1 - 4.1e-95 318.9 0.0 4.9e-95 318.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KZN90645.1 - 7e-12 46.2 0.0 1.6e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ribosomal_S19 PF00203.21 KZN90646.1 - 5.6e-33 112.7 0.3 7.9e-33 112.2 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_60s PF00428.19 KZN90647.1 - 2.7e-26 92.0 12.0 3.1e-26 91.8 12.0 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3138 PF11336.8 KZN90647.1 - 0.14 10.8 2.4 0.14 10.7 2.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) SPT2 PF08243.11 KZN90648.1 - 1.6e-07 31.9 12.1 1.6e-07 31.9 12.1 1.9 2 0 0 2 2 2 1 SPT2 chromatin protein TFIIA PF03153.13 KZN90648.1 - 1.2 9.0 13.6 2.1 8.3 13.6 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Carb_kinase PF01256.17 KZN90649.1 - 1.2e-42 146.1 0.1 2.4e-41 141.8 0.1 2.1 1 1 0 1 1 1 1 Carbohydrate kinase EGF_CA PF07645.15 KZN90650.1 - 1.1e-05 25.6 5.9 1.1e-05 25.6 5.9 2.2 2 1 0 2 2 2 1 Calcium-binding EGF domain EGF_3 PF12947.7 KZN90650.1 - 3.5e-05 23.9 5.7 3.5e-05 23.9 5.7 2.3 3 1 0 3 3 3 1 EGF domain FXa_inhibition PF14670.6 KZN90650.1 - 0.00044 20.5 1.7 0.00044 20.5 1.7 2.4 2 1 0 2 2 2 1 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KZN90650.1 - 0.0025 17.7 0.2 0.0025 17.7 0.2 2.6 4 0 0 4 4 4 1 Complement Clr-like EGF-like hEGF PF12661.7 KZN90650.1 - 0.15 12.8 3.0 0.15 12.8 3.0 2.7 3 0 0 3 3 3 0 Human growth factor-like EGF MCM PF00493.23 KZN90651.1 - 7.9e-103 342.4 0.0 1.3e-102 341.6 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KZN90651.1 - 3.4e-32 110.9 0.4 5.9e-32 110.2 0.4 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 KZN90651.1 - 2.8e-20 72.9 0.7 8.2e-20 71.3 0.7 1.8 1 0 0 1 1 1 1 MCM N-terminal domain MCM_lid PF17855.1 KZN90651.1 - 3.7e-19 68.9 1.5 9e-19 67.7 1.5 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KZN90651.1 - 3.2e-07 29.9 0.0 2.5e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KZN90651.1 - 1.5e-06 28.2 0.0 3.7e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 KZN90651.1 - 0.00053 19.8 0.0 0.0016 18.2 0.0 1.8 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 KZN90651.1 - 0.023 14.6 0.0 0.083 12.8 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KZN90651.1 - 0.15 11.8 0.0 0.88 9.2 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase_C PF13335.6 KZN90651.1 - 0.15 12.7 0.5 0.83 10.3 0.2 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal AAA PF00004.29 KZN90652.1 - 2.7e-53 179.9 0.0 3.6e-43 147.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KZN90652.1 - 1.3e-29 102.4 0.8 2.7e-29 101.4 0.8 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 KZN90652.1 - 4.3e-14 52.0 0.1 7.5e-08 32.0 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KZN90652.1 - 1.2e-07 32.2 5.9 0.011 16.1 0.1 4.4 3 2 1 5 5 4 2 AAA ATPase domain AAA_2 PF07724.14 KZN90652.1 - 1.7e-06 28.3 0.0 0.092 12.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) NACHT PF05729.12 KZN90652.1 - 4.6e-06 26.6 0.5 0.022 14.7 0.0 3.4 3 0 0 3 3 3 2 NACHT domain AAA_18 PF13238.6 KZN90652.1 - 1.4e-05 25.6 0.6 0.19 12.3 0.5 3.4 2 1 0 2 2 2 2 AAA domain TsaE PF02367.17 KZN90652.1 - 1.5e-05 25.0 0.1 0.034 14.2 0.1 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KZN90652.1 - 1.8e-05 25.0 0.5 0.77 10.0 0.1 3.5 2 1 1 3 3 3 2 AAA domain RuvB_N PF05496.12 KZN90652.1 - 3.1e-05 23.8 0.0 0.0086 15.8 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KZN90652.1 - 5.5e-05 23.0 0.2 0.047 13.4 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.12 KZN90652.1 - 0.00085 18.6 0.0 0.33 10.2 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_5 PF07728.14 KZN90652.1 - 0.0013 18.7 0.1 1 9.4 0.0 3.3 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) PEX-2N PF09263.10 KZN90652.1 - 0.0025 18.1 0.6 0.23 11.8 0.8 3.1 2 1 0 2 2 2 1 Peroxisome biogenesis factor 1, N-terminal AAA_33 PF13671.6 KZN90652.1 - 0.0027 17.9 0.0 0.14 12.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KZN90652.1 - 0.0045 16.6 0.6 2.8 7.5 0.2 3.2 2 1 0 3 3 3 1 AAA domain AAA_28 PF13521.6 KZN90652.1 - 0.0056 16.9 0.0 2.2 8.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KZN90652.1 - 0.0064 16.5 0.0 2.1 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KZN90652.1 - 0.008 15.4 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_19 PF13245.6 KZN90652.1 - 0.011 16.1 0.1 0.16 12.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KZN90652.1 - 0.017 14.5 0.2 0.18 11.1 0.1 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KZN90652.1 - 0.018 15.4 0.0 8.2 6.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.15 KZN90652.1 - 0.043 13.7 0.0 0.62 10.0 0.0 2.2 2 0 0 2 2 2 0 NTPase Viral_helicase1 PF01443.18 KZN90652.1 - 0.05 13.3 0.0 0.45 10.2 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 KZN90652.1 - 0.061 12.8 0.0 3 7.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF2075 PF09848.9 KZN90652.1 - 0.066 12.4 0.0 4.5 6.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 KZN90652.1 - 0.071 13.6 0.0 24 5.5 0.0 2.6 2 0 0 2 2 2 0 ABC transporter T2SSE PF00437.20 KZN90652.1 - 0.078 12.0 0.0 0.25 10.4 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 KZN90652.1 - 0.096 12.4 0.0 4.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 KZN90652.1 - 0.13 11.6 0.1 8.6 5.6 0.1 2.3 2 0 0 2 2 2 0 KaiC AAA_17 PF13207.6 KZN90652.1 - 0.16 12.4 0.0 1.8 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KZN90652.1 - 0.16 11.8 0.0 7.3 6.4 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea cobW PF02492.19 KZN90652.1 - 0.24 11.0 1.4 4.6 6.8 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RT_RNaseH PF17917.1 KZN90654.1 - 1.4e-15 57.4 0.0 2.3e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KZN90654.1 - 6.9e-13 48.5 0.0 2.7e-11 43.4 0.0 2.2 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SET PF00856.28 KZN90655.1 - 1.9e-14 54.4 0.0 5.8e-14 52.8 0.0 1.8 2 0 0 2 2 2 1 SET domain zf-MYND PF01753.18 KZN90655.1 - 2.2e-08 34.1 10.0 2.2e-08 34.1 10.0 2.0 2 0 0 2 2 2 1 MYND finger CPSase_L_D2 PF02786.17 KZN90656.1 - 2.8e-107 357.0 0.0 1.7e-84 282.6 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KZN90656.1 - 1.5e-41 141.6 0.1 3.7e-41 140.3 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Dala_Dala_lig_C PF07478.13 KZN90656.1 - 7.6e-18 64.8 0.2 9.4e-08 31.8 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KZN90656.1 - 5.4e-17 61.9 0.0 1.5e-07 31.2 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KZN90656.1 - 2.5e-12 46.7 0.0 1.9e-05 24.4 0.0 3.0 3 1 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 KZN90656.1 - 0.0001 21.8 0.8 0.035 13.6 0.1 2.8 3 0 0 3 3 3 2 ATP-grasp domain GARS_A PF01071.19 KZN90656.1 - 0.002 17.9 0.0 1 9.1 0.0 2.6 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 KZN90656.1 - 0.0044 16.6 0.0 1 8.9 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain YfkB PF08756.10 KZN90657.1 - 0.11 12.3 0.0 1.2 8.9 0.0 2.5 2 1 1 3 3 3 0 YfkB-like domain SpoIIIAH PF12685.7 KZN90658.1 - 0.37 10.6 10.9 0.66 9.8 10.9 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein Zip PF02535.22 KZN90658.1 - 5.8 6.0 5.6 8.2 5.5 5.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CcdA PF07362.12 KZN90659.1 - 0.092 13.2 1.4 19 5.8 0.0 3.3 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA CREPT PF16566.5 KZN90659.1 - 0.81 9.8 9.6 1.6 8.9 0.0 4.4 4 1 1 5 5 5 0 Cell-cycle alteration and expression-elevated protein in tumour DUF2046 PF09755.9 KZN90660.1 - 0.0013 18.0 0.1 0.2 10.9 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) ATG16 PF08614.11 KZN90660.1 - 0.024 14.9 1.5 0.024 14.9 1.5 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 KZN90660.1 - 0.034 14.8 4.0 3.2 8.4 1.3 2.4 2 0 0 2 2 2 0 SlyX bZIP_2 PF07716.15 KZN90660.1 - 0.046 13.8 7.2 0.11 12.7 0.8 2.4 2 0 0 2 2 2 0 Basic region leucine zipper DegS PF05384.11 KZN90660.1 - 0.049 13.1 0.8 0.049 13.1 0.8 1.9 2 0 0 2 2 2 0 Sensor protein DegS DUF4454 PF14628.6 KZN90660.1 - 0.092 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4454) End3 PF12761.7 KZN90660.1 - 0.17 12.1 3.9 0.82 9.8 0.3 2.3 2 1 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 FlaC_arch PF05377.11 KZN90660.1 - 0.21 12.0 2.1 0.32 11.4 0.2 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Pox_A_type_inc PF04508.12 KZN90660.1 - 0.27 11.2 4.5 0.68 9.9 4.5 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat dCache_2 PF08269.11 KZN90660.1 - 0.3 10.2 1.0 0.44 9.7 1.0 1.2 1 0 0 1 1 1 0 Cache domain Csm1_N PF18504.1 KZN90660.1 - 0.35 11.2 4.7 1.4 9.3 2.3 2.2 2 0 0 2 2 2 0 Csm1 N-terminal domain Rho_Binding PF08912.11 KZN90660.1 - 0.9 10.4 4.6 0.58 11.0 1.5 2.0 2 0 0 2 2 2 0 Rho Binding G-gamma PF00631.22 KZN90660.1 - 1.6 8.8 4.7 23 5.1 0.1 2.4 2 0 0 2 2 2 0 GGL domain HIP1_clath_bdg PF16515.5 KZN90660.1 - 2.9 8.6 8.9 5.7 7.6 1.5 2.5 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CENP-F_N PF10481.9 KZN90660.1 - 3.4 7.2 11.8 0.042 13.5 1.1 2.1 1 1 0 2 2 2 0 Cenp-F N-terminal domain RAP1 PF07218.11 KZN90660.1 - 4.5 5.4 9.3 6.5 4.9 9.3 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CCDC14 PF15254.6 KZN90660.1 - 5.6 5.5 16.5 0.081 11.6 1.7 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 14 RRM_1 PF00076.22 KZN90661.1 - 2.4e-08 33.7 0.0 5.2e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KZN90661.1 - 4.5e-08 33.0 0.0 7.6e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KZN90661.1 - 0.022 14.6 0.1 0.061 13.2 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif IBN_N PF03810.19 KZN90663.1 - 2.7e-16 59.2 0.1 1e-12 47.8 0.0 3.9 4 0 0 4 4 4 1 Importin-beta N-terminal domain Cse1 PF08506.10 KZN90663.1 - 1.5e-09 37.2 0.0 3.1e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.12 KZN90663.1 - 0.00059 19.9 0.4 0.017 15.2 0.0 3.1 3 0 0 3 3 3 1 Exportin 1-like protein CAS_CSE1 PF03378.15 KZN90663.1 - 0.0015 17.1 1.7 0.41 9.1 0.0 2.8 3 0 0 3 3 3 2 CAS/CSE protein, C-terminus RTP1_C1 PF10363.9 KZN90663.1 - 0.0016 18.6 0.7 0.23 11.6 0.1 3.1 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RIX1 PF08167.12 KZN90663.1 - 0.045 13.5 0.1 2.8 7.7 0.0 3.8 3 1 1 4 4 4 0 rRNA processing/ribosome biogenesis HEAT_2 PF13646.6 KZN90663.1 - 0.05 14.0 0.6 6.5 7.2 0.0 3.6 3 0 0 3 3 3 0 HEAT repeats SDA1 PF05285.12 KZN90663.1 - 2.4 7.5 8.2 4.2 6.7 8.2 1.3 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 KZN90663.1 - 3.7 5.5 16.2 10 4.1 16.2 1.7 1 0 0 1 1 1 0 DNA polymerase phi HEAT_EZ PF13513.6 KZN90663.1 - 5.7 7.6 7.0 26 5.5 0.7 4.8 4 3 0 4 4 4 0 HEAT-like repeat BUD22 PF09073.10 KZN90663.1 - 7.8 5.7 7.0 12 5.1 7.0 1.2 1 0 0 1 1 1 0 BUD22 DSHCT PF08148.12 KZN90664.1 - 1.5e-52 177.6 0.7 4.1e-52 176.1 0.7 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 KZN90664.1 - 1.2e-40 138.5 0.1 2.6e-40 137.3 0.1 1.6 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 KZN90664.1 - 1.5e-23 84.1 0.2 3.4e-23 82.9 0.2 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 KZN90664.1 - 1.7e-18 67.0 0.1 5.5e-18 65.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KZN90664.1 - 4.5e-06 27.0 0.0 1.2e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KZN90664.1 - 1.3e-05 25.3 0.0 2.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MFS_1 PF07690.16 KZN90665.1 - 5.9e-20 71.5 24.1 8.1e-20 71.0 21.2 1.9 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF2415 PF10313.9 KZN90667.1 - 7.9e-17 60.9 0.1 6.5e-16 58.0 0.1 2.2 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 KZN90667.1 - 0.17 12.2 0.0 24 5.3 0.0 3.4 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain HSP70 PF00012.20 KZN90668.1 - 1.3e-262 872.4 18.7 1.5e-262 872.2 18.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KZN90668.1 - 2.5e-15 56.1 5.4 3.1e-14 52.6 2.1 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 KZN90668.1 - 0.0041 16.9 0.0 0.01 15.6 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain THUMP PF02926.17 KZN90668.1 - 0.017 15.2 1.5 1.7 8.8 1.2 2.7 2 0 0 2 2 2 0 THUMP domain Raco_middle PF17651.1 KZN90668.1 - 0.086 12.5 0.2 5.1 6.7 0.0 2.7 2 0 0 2 2 2 0 RACo middle region Tom22 PF04281.13 KZN90668.1 - 7.3 6.4 12.3 1 9.2 7.4 2.1 1 1 1 2 2 2 0 Mitochondrial import receptor subunit Tom22 RRN3 PF05327.11 KZN90668.1 - 7.5 5.0 11.6 12 4.3 11.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Methyltransf_16 PF10294.9 KZN90670.1 - 1.2e-09 38.2 0.0 0.00054 19.7 0.0 2.8 3 0 0 3 3 3 2 Lysine methyltransferase AMP-binding PF00501.28 KZN90671.1 - 9.2e-90 301.2 0.0 1.4e-89 300.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KZN90671.1 - 0.00051 21.0 0.5 0.0014 19.6 0.5 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NDT80_PhoG PF05224.12 KZN90673.1 - 1.2e-36 126.7 0.0 2.1e-36 125.9 0.0 1.4 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family eIF3g PF12353.8 KZN90674.1 - 1.6e-44 151.3 4.4 2.3e-44 150.8 4.4 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KZN90674.1 - 1e-14 54.1 0.0 1.6e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 KZN90674.1 - 0.025 14.9 1.1 0.057 13.7 0.2 1.9 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 Glyco_transf_34 PF05637.12 KZN90675.1 - 1.5e-08 34.7 0.1 2.2e-07 30.8 0.1 2.0 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 KZN90675.1 - 0.00064 19.8 0.0 0.00097 19.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Transp_cyt_pur PF02133.15 KZN90676.1 - 1.5e-44 152.5 36.0 1.9e-44 152.2 36.0 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Rer1 PF03248.13 KZN90676.1 - 7.4 6.3 7.4 0.77 9.5 1.1 2.6 2 1 0 2 2 2 0 Rer1 family HMA PF00403.26 KZN90678.1 - 6.9e-14 52.0 0.5 1.4e-13 51.0 0.0 1.8 2 0 0 2 2 2 1 Heavy-metal-associated domain Sod_Cu PF00080.20 KZN90678.1 - 3.7e-09 36.9 0.0 5.2e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Pkinase PF00069.25 KZN90679.1 - 5.8e-62 209.4 0.0 8e-62 209.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN90679.1 - 1.5e-26 93.2 0.0 3.8e-26 91.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Glyco_hydro_3_C PF01915.22 KZN90679.1 - 7.8e-14 52.1 0.1 1.7e-13 51.0 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KZN90679.1 - 1.5e-07 31.4 0.2 3.3e-07 30.3 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Haspin_kinase PF12330.8 KZN90679.1 - 0.044 12.7 0.0 0.07 12.1 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KZN90679.1 - 0.43 9.3 1.3 0.86 8.3 1.3 1.5 1 1 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KZN90679.1 - 1.5 8.6 3.9 0.27 11.1 0.1 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family VIT PF08487.10 KZN90680.1 - 7.7e-32 109.8 0.0 1.8e-31 108.6 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KZN90680.1 - 2.9e-28 98.8 0.0 5.5e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KZN90680.1 - 1.1e-14 55.1 0.2 2.1e-14 54.1 0.2 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 KZN90680.1 - 1.2e-11 44.3 0.1 4.4e-11 42.5 0.1 2.0 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 KZN90680.1 - 4.9e-10 40.0 0.0 9.9e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KZN90680.1 - 0.0019 17.7 0.5 0.0038 16.7 0.1 1.6 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein Methyltransf_28 PF02636.17 KZN90683.1 - 7.1e-81 271.7 0.0 9e-81 271.3 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Rhodanese PF00581.20 KZN90684.1 - 8e-12 45.6 0.0 1e-11 45.3 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Flavodoxin_3 PF12641.7 KZN90684.1 - 0.067 12.9 0.0 0.074 12.7 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin domain 3Beta_HSD PF01073.19 KZN90684.1 - 0.14 11.2 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ribosomal_S21 PF01165.20 KZN90685.1 - 6.5e-11 41.8 0.5 1.4e-10 40.7 0.5 1.6 1 0 0 1 1 1 1 Ribosomal protein S21 PGI PF00342.19 KZN90687.1 - 1.3e-237 789.2 1.3 1.5e-237 788.9 1.3 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase PWI PF01480.17 KZN90688.1 - 7.8e-16 58.2 0.5 1.7e-15 57.1 0.5 1.6 1 0 0 1 1 1 1 PWI domain MR_MLE_C PF13378.6 KZN90689.1 - 5e-60 202.8 0.0 8.1e-60 202.1 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KZN90689.1 - 2.3e-06 27.8 0.0 5.6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Peptidase_Prp PF04327.12 KZN90689.1 - 0.037 14.3 0.0 0.091 13.0 0.0 1.6 1 0 0 1 1 1 0 Cysteine protease Prp F-box-like PF12937.7 KZN90690.1 - 9.4e-10 38.2 1.6 3.4e-09 36.5 1.6 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN90690.1 - 0.00076 19.3 1.5 0.0023 17.8 1.5 1.9 1 1 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KZN90690.1 - 0.019 14.8 0.1 0.039 13.8 0.1 1.5 1 0 0 1 1 1 0 F-box DUF1682 PF07946.14 KZN90691.1 - 2.2e-115 385.3 2.4 2.6e-115 385.1 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) YajC PF02699.15 KZN90691.1 - 0.053 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit RbsD_FucU PF05025.13 KZN90691.1 - 0.093 13.2 0.2 0.19 12.2 0.2 1.5 1 1 0 1 1 1 0 RbsD / FucU transport protein family TIM21 PF08294.11 KZN90695.1 - 3.1e-40 137.4 0.0 4e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 KZN90695.1 - 0.00037 20.2 0.0 0.00087 19.0 0.0 1.6 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 ArfGap PF01412.18 KZN90696.1 - 1.9e-33 115.0 0.7 3.2e-33 114.3 0.7 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Mcm10 PF09332.11 KZN90696.1 - 0.16 11.3 2.0 0.37 10.2 2.0 1.6 1 0 0 1 1 1 0 Mcm10 replication factor Pterin_bind PF00809.22 KZN90697.1 - 1.4e-79 267.2 0.0 1.8e-79 266.9 0.0 1.1 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 KZN90697.1 - 3.3e-35 121.0 0.0 5.8e-35 120.2 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) ThiP_synth PF10120.9 KZN90697.1 - 0.086 12.5 0.7 0.24 11.0 0.2 1.9 2 0 0 2 2 2 0 Thiamine-phosphate synthase ArabFuran-catal PF09206.11 KZN90698.1 - 9.4e-153 508.1 14.2 1.6e-152 507.4 14.2 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.13 KZN90698.1 - 4e-56 188.9 2.3 6.1e-56 188.3 2.3 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain adh_short PF00106.25 KZN90700.1 - 8.6e-17 61.2 0.1 1.4e-16 60.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN90700.1 - 6.1e-14 52.1 0.2 7.4e-14 51.9 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN90700.1 - 0.0013 18.6 0.1 0.002 18.1 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KZN90700.1 - 0.0016 18.3 0.2 0.0025 17.7 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding AAA PF00004.29 KZN90701.1 - 1.3e-17 64.4 0.0 2.8e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KZN90701.1 - 0.0001 22.7 0.0 0.0003 21.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KZN90701.1 - 0.00088 19.6 0.0 0.0046 17.2 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KZN90701.1 - 0.0039 17.2 0.0 0.012 15.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Zot PF05707.12 KZN90701.1 - 0.024 14.3 0.1 0.21 11.2 0.1 2.1 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Sigma54_activat PF00158.26 KZN90701.1 - 0.077 12.7 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain CPT PF07931.12 KZN90701.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Tim17 PF02466.19 KZN90703.1 - 2.7e-31 108.2 7.8 3.4e-31 107.9 7.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Ank_2 PF12796.7 KZN90704.1 - 1.3e-137 448.7 0.1 7.6e-18 64.9 0.0 12.1 2 1 8 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN90704.1 - 2.3e-95 311.9 8.1 2e-10 41.0 0.0 16.1 4 1 15 19 19 19 17 Ankyrin repeats (many copies) Ank PF00023.30 KZN90704.1 - 3.7e-94 305.4 23.3 7.6e-06 26.2 0.0 20.4 19 2 2 21 21 21 18 Ankyrin repeat Ank_5 PF13857.6 KZN90704.1 - 2.7e-89 292.0 10.8 6.4e-09 35.9 0.0 17.7 2 1 16 19 19 19 18 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN90704.1 - 1.7e-82 261.4 7.5 0.0016 18.8 0.0 21.4 21 0 0 21 21 21 16 Ankyrin repeat HeLo PF14479.6 KZN90704.1 - 1.3e-17 64.3 0.6 1.7e-15 57.4 0.6 2.5 1 1 0 1 1 1 1 Prion-inhibition and propagation NACHT PF05729.12 KZN90704.1 - 0.0002 21.4 0.1 0.2 11.6 0.0 2.5 1 1 1 2 2 2 2 NACHT domain DUF1521 PF07481.11 KZN90704.1 - 0.00038 20.5 3.7 1.5 8.8 0.1 4.8 2 1 4 6 6 6 1 Domain of Unknown Function (DUF1521) NB-ARC PF00931.22 KZN90704.1 - 0.22 10.7 0.7 5.9 6.0 0.0 2.3 1 1 0 2 2 2 0 NB-ARC domain ZZ PF00569.17 KZN90704.1 - 0.53 10.1 5.9 1 9.2 5.9 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type NAD_binding_10 PF13460.6 KZN90706.1 - 4.9e-19 68.9 0.0 1.5e-18 67.4 0.0 1.8 2 1 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KZN90706.1 - 6.4e-17 61.9 0.0 9.1e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Shikimate_DH PF01488.20 KZN90706.1 - 2.4e-07 30.9 0.1 6.4e-07 29.5 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 KZN90706.1 - 0.00068 19.8 0.3 0.0058 16.8 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.21 KZN90706.1 - 0.0023 17.5 0.0 0.0047 16.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KZN90706.1 - 0.0024 17.8 0.0 0.01 15.8 0.0 1.9 1 1 1 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KZN90706.1 - 0.0033 18.0 0.4 0.04 14.5 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 KZN90706.1 - 0.071 12.1 0.0 0.19 10.7 0.0 1.8 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family OAD_gamma PF04277.13 KZN90708.1 - 0.006 17.1 0.3 0.016 15.8 0.0 1.8 2 0 0 2 2 2 1 Oxaloacetate decarboxylase, gamma chain PRIMA1 PF16101.5 KZN90708.1 - 5.4 7.1 7.1 0.11 12.5 0.6 1.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 BID PF06393.11 KZN90709.1 - 0.089 12.3 0.5 0.13 11.7 0.5 1.2 1 0 0 1 1 1 0 BH3 interacting domain (BID) NMO PF03060.15 KZN90710.1 - 2.6e-54 184.9 1.5 3.5e-54 184.4 1.5 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KZN90710.1 - 3.3e-12 46.1 1.8 5.9e-12 45.2 1.8 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KZN90710.1 - 9.4e-08 31.5 1.6 1.4e-07 30.9 1.6 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KZN90710.1 - 0.00012 21.3 2.2 0.00023 20.4 2.2 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 KZN90710.1 - 0.004 16.4 0.4 0.0062 15.8 0.4 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase TPR_1 PF00515.28 KZN90711.1 - 2.7e-13 49.1 6.8 4.2e-06 26.4 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KZN90711.1 - 2e-12 46.2 5.3 0.0008 19.3 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KZN90711.1 - 6.9e-09 35.2 0.4 0.00016 21.6 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KZN90711.1 - 7e-09 35.9 0.4 1e-05 25.7 0.1 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KZN90711.1 - 2.2e-05 24.2 1.2 0.00085 19.2 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat PB1 PF00564.24 KZN90711.1 - 3.1e-05 23.8 0.0 6.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 PB1 domain TPR_16 PF13432.6 KZN90711.1 - 6.9e-05 23.4 0.5 0.011 16.3 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KZN90711.1 - 8.6e-05 22.1 1.2 0.0011 18.6 0.1 2.9 2 1 1 3 3 3 1 TPR repeat TPR_9 PF13371.6 KZN90711.1 - 9.3e-05 22.5 0.2 0.19 11.9 0.0 3.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 KZN90711.1 - 0.00012 22.5 0.5 3.1 8.6 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KZN90711.1 - 0.16 11.9 1.0 3.1 7.8 0.0 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat Di19_C PF14571.6 KZN90712.1 - 0.019 15.5 0.2 0.025 15.1 0.2 1.2 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal Syntaxin-18_N PF10496.9 KZN90714.1 - 2.8e-12 46.7 1.5 1.7e-11 44.2 0.2 2.5 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 KZN90714.1 - 0.00016 21.6 0.1 0.00051 20.0 0.0 2.0 2 0 0 2 2 2 1 SNARE domain BLOC1_2 PF10046.9 KZN90714.1 - 0.057 13.7 3.8 0.25 11.7 1.3 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF16 PF01519.16 KZN90714.1 - 1.4 9.5 4.0 2.9 8.4 1.4 2.5 3 0 0 3 3 3 0 Protein of unknown function DUF16 Aminotran_1_2 PF00155.21 KZN90715.1 - 1.9e-83 280.6 0.0 2.6e-83 280.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II zf-RING_2 PF13639.6 KZN90716.1 - 1.3e-13 51.0 5.7 2.6e-13 50.1 5.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KZN90716.1 - 5.3e-10 38.9 3.2 9.3e-10 38.1 3.2 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KZN90716.1 - 8.2e-09 35.2 6.3 1.3e-08 34.5 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KZN90716.1 - 3.6e-08 33.2 4.2 6.6e-08 32.3 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KZN90716.1 - 3.5e-07 30.4 8.0 1.4e-06 28.5 8.0 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KZN90716.1 - 5.5e-05 23.1 2.1 5.5e-05 23.1 2.1 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KZN90716.1 - 6e-05 22.9 2.5 6e-05 22.9 2.5 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KZN90716.1 - 8.7e-05 22.3 1.8 8.7e-05 22.3 1.8 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KZN90716.1 - 0.00011 22.0 6.8 0.0014 18.4 6.9 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KZN90716.1 - 0.00014 21.9 2.4 0.00032 20.7 2.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KZN90716.1 - 0.00063 19.5 4.0 0.0012 18.5 4.0 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KZN90716.1 - 0.029 14.5 5.3 0.029 14.5 5.3 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 KZN90716.1 - 0.033 14.5 1.8 0.06 13.7 1.8 1.4 1 0 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 KZN90716.1 - 0.14 11.8 1.9 0.32 10.7 1.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 KZN90716.1 - 0.24 11.4 2.5 0.28 11.2 0.6 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 KZN90716.1 - 4.1 7.7 8.9 2 8.7 5.2 2.4 2 1 0 2 2 1 0 FANCL C-terminal domain NACHT PF05729.12 KZN90717.1 - 0.033 14.1 0.1 0.11 12.4 0.1 2.0 1 0 0 1 1 1 0 NACHT domain PhyH PF05721.13 KZN90718.1 - 1.6e-24 87.3 0.1 2.5e-24 86.7 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MS_channel PF00924.18 KZN90719.1 - 4.2e-20 72.2 0.5 8.4e-20 71.2 0.5 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KZN90719.1 - 0.00099 18.5 0.3 0.003 17.0 0.3 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KZN90719.1 - 0.0047 16.8 0.1 0.017 15.0 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KZN90719.1 - 0.02 14.4 0.1 0.06 12.9 0.1 1.8 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 KZN90719.1 - 0.038 14.4 0.1 0.11 13.0 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair Mgm101p PF06420.12 KZN90720.1 - 1.7e-86 288.0 0.0 2.3e-86 287.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 CHCH PF06747.13 KZN90721.1 - 3.1e-07 30.3 8.9 4.4e-07 29.9 8.9 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 KZN90721.1 - 0.00066 19.6 2.8 0.082 12.9 0.6 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Ndufs5 PF10200.9 KZN90721.1 - 0.004 17.4 1.3 0.0048 17.1 1.3 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Cmc1 PF08583.10 KZN90721.1 - 0.0043 17.0 6.6 0.046 13.8 0.8 2.0 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 KZN90721.1 - 0.13 12.6 4.3 0.18 12.2 4.3 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) BPL_N PF09825.9 KZN90722.1 - 3.6e-148 493.7 0.0 4.4e-148 493.4 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 KZN90722.1 - 2.8e-25 88.7 0.0 4.7e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 KZN90722.1 - 0.00078 19.3 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain MUG113 PF13455.6 KZN90723.1 - 3.9e-29 101.1 0.3 7.5e-29 100.2 0.3 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 KZN90723.1 - 2.1e-27 95.7 1.4 2.5e-27 95.4 0.2 1.8 2 0 0 2 2 2 1 T5orf172 domain DUF4887 PF16228.5 KZN90723.1 - 3.1 7.9 10.4 6 7.0 10.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) DLH PF01738.18 KZN90724.1 - 3.6e-16 59.4 0.0 1.2e-15 57.7 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 KZN90724.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 KZN90724.1 - 0.17 11.1 0.0 0.56 9.4 0.0 1.8 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KZN90725.1 - 2.1e-47 161.7 0.0 2.6e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KZN90725.1 - 0.0024 16.8 0.0 0.0034 16.3 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KZN90725.1 - 0.003 16.5 0.1 0.0064 15.4 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_1 PF00561.20 KZN90725.1 - 0.007 16.0 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KZN90725.1 - 0.15 12.2 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Chlorophyllase2 PF12740.7 KZN90725.1 - 0.15 11.0 0.0 1.8 7.4 0.0 2.0 2 0 0 2 2 2 0 Chlorophyllase enzyme CN_hydrolase PF00795.22 KZN90726.1 - 4.4e-48 163.9 0.0 5.1e-48 163.7 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Ank_2 PF12796.7 KZN90727.1 - 7.4e-20 71.3 4.7 2.5e-07 31.2 0.1 4.7 3 1 2 5 5 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN90727.1 - 1.8e-18 66.7 0.0 2.7e-05 24.6 0.0 5.0 4 1 1 5 5 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KZN90727.1 - 2.5e-11 43.6 6.8 0.094 13.1 0.1 6.5 2 1 5 7 7 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN90727.1 - 2.6e-10 39.6 6.1 2.4 9.0 0.1 6.9 6 0 0 6 6 6 3 Ankyrin repeat NACHT PF05729.12 KZN90727.1 - 6.6e-09 35.9 0.0 1.7e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KZN90727.1 - 9.5e-08 32.6 1.2 5.7e-07 30.1 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KZN90727.1 - 0.00023 21.4 0.0 0.0013 19.0 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA PF00004.29 KZN90727.1 - 0.013 15.9 0.1 0.088 13.2 0.1 2.5 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KZN90727.1 - 0.053 13.9 0.0 0.59 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KZN90727.1 - 0.067 13.6 0.0 0.22 11.9 0.0 1.9 1 0 0 1 1 1 0 RNA helicase DUF3447 PF11929.8 KZN90727.1 - 0.07 13.1 0.0 7.8 6.5 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF3447) NB-ARC PF00931.22 KZN90727.1 - 0.073 12.2 0.0 1.5 8.0 0.0 2.2 1 1 0 1 1 1 0 NB-ARC domain FRB_dom PF08771.11 KZN90727.1 - 0.14 12.6 2.5 17 5.9 0.1 3.3 3 0 0 3 3 2 0 FKBP12-rapamycin binding domain Ank PF00023.30 KZN90727.1 - 0.71 10.4 7.5 1.1e+02 3.5 0.2 5.5 4 2 0 4 4 4 0 Ankyrin repeat Aldedh PF00171.22 KZN90728.1 - 9.3e-161 535.4 0.8 2.4e-128 428.6 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Mpt_N PF09176.11 KZN90728.1 - 0.16 12.1 0.0 0.91 9.7 0.0 2.3 2 0 0 2 2 2 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal DHDPS PF00701.22 KZN90729.1 - 1.5e-60 204.4 0.0 1.6e-60 204.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Fungal_trans_2 PF11951.8 KZN90730.1 - 8.8e-49 166.3 2.9 1.2e-48 165.9 2.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN90730.1 - 1.7e-09 37.7 7.9 3.4e-09 36.7 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMN_dh PF01070.18 KZN90731.1 - 2.2e-117 392.0 0.0 2.6e-117 391.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KZN90731.1 - 3.1e-07 29.7 0.0 5.5e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KZN90731.1 - 0.00015 21.0 0.0 0.00025 20.3 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KZN90731.1 - 0.00082 18.9 0.0 0.026 14.0 0.0 2.2 1 1 0 2 2 2 1 Histidine biosynthesis protein NMO PF03060.15 KZN90731.1 - 0.0052 16.2 0.0 0.0075 15.7 0.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KZN90731.1 - 0.007 15.7 0.0 0.28 10.4 0.0 2.3 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 KZN90731.1 - 0.0072 15.6 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase CYSTM PF12734.7 KZN90732.1 - 1 9.7 19.3 1.6 9.1 19.3 1.5 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance bZIP_1 PF00170.21 KZN90733.1 - 0.0017 18.4 1.7 0.0041 17.2 1.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor Tropomyosin_1 PF12718.7 KZN90733.1 - 0.02 15.0 0.8 0.036 14.2 0.8 1.3 1 0 0 1 1 1 0 Tropomyosin like p450 PF00067.22 KZN90734.1 - 6.9e-59 199.8 0.0 9.3e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cellulase PF00150.18 KZN90735.1 - 3.7e-55 187.3 1.8 5.2e-55 186.9 1.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KZN90735.1 - 1.9e-13 50.1 11.2 1.9e-13 50.1 11.2 2.3 3 0 0 3 3 3 1 Fungal cellulose binding domain TANGO2 PF05742.12 KZN90736.1 - 1.2e-75 254.9 0.0 1.3e-75 254.7 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 TB2_DP1_HVA22 PF03134.19 KZN90737.1 - 3.4e-24 84.6 5.8 5.4e-24 83.9 5.8 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family CoA_binding_3 PF13727.6 KZN90737.1 - 0.1 12.6 0.5 0.18 11.8 0.5 1.4 1 0 0 1 1 1 0 CoA-binding domain MIF4G PF02854.19 KZN90739.1 - 2.3e-51 174.4 0.0 3.6e-51 173.8 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 KZN90739.1 - 1.5e-19 69.9 0.3 4.8e-19 68.3 0.3 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Usp PF00582.26 KZN90740.1 - 2.3e-22 80.0 1.6 8.7e-22 78.1 0.1 2.5 3 0 0 3 3 3 1 Universal stress protein family BUD22 PF09073.10 KZN90741.1 - 0.045 13.1 10.3 0.056 12.8 10.3 1.1 1 0 0 1 1 1 0 BUD22 Pro-kuma_activ PF09286.11 KZN90743.1 - 2.6e-50 170.4 0.1 1.5e-49 167.9 0.0 2.1 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KZN90743.1 - 0.095 11.9 0.1 0.43 9.8 0.1 1.9 1 1 0 1 1 1 0 Subtilase family AICARFT_IMPCHas PF01808.18 KZN90744.1 - 4.9e-90 302.0 0.0 7.8e-90 301.3 0.0 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KZN90744.1 - 3.6e-25 88.0 0.1 7.7e-25 86.9 0.1 1.6 1 0 0 1 1 1 1 MGS-like domain INSIG PF07281.12 KZN90745.1 - 6.9e-75 251.3 1.0 9.5e-75 250.9 1.0 1.2 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) DEAD PF00270.29 KZN90747.1 - 1.1e-47 162.0 0.0 3.9e-47 160.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KZN90747.1 - 9.9e-33 112.8 0.0 2.8e-32 111.4 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KZN90747.1 - 0.0034 17.4 0.0 0.0059 16.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KZN90747.1 - 0.046 13.1 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 KZN90747.1 - 0.16 11.1 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase UTP25 PF06862.12 KZN90747.1 - 0.27 10.0 0.0 0.46 9.2 0.0 1.3 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Pro_isomerase PF00160.21 KZN90748.1 - 1.1e-47 162.2 0.2 1.4e-47 161.9 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S13 PF00416.22 KZN90749.1 - 8.7e-16 58.5 1.2 1.3e-15 57.9 1.2 1.3 1 1 0 1 1 1 1 Ribosomal protein S13/S18 Ntox8 PF15545.6 KZN90749.1 - 0.047 13.8 0.2 0.062 13.4 0.2 1.3 1 0 0 1 1 1 0 Bacterial toxin 8 WD40 PF00400.32 KZN90750.1 - 1.8e-22 79.2 14.1 4.8e-07 30.4 0.2 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.12 KZN90750.1 - 7.6e-20 71.2 0.2 1.5e-19 70.2 0.2 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 KZN90750.1 - 4.4e-06 25.6 0.5 0.00063 18.5 0.1 2.7 1 1 1 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KZN90750.1 - 0.087 13.1 0.0 3.1 8.2 0.0 3.0 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Zw10 PF06248.13 KZN90751.1 - 1.2e-13 50.5 0.6 1.2e-13 50.5 0.6 2.0 2 1 0 2 2 2 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 KZN90751.1 - 3.1e-07 30.3 0.0 6.7e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal Peptidase_M16_C PF05193.21 KZN90752.1 - 4.6e-14 52.8 0.0 6.9e-11 42.5 0.0 3.0 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KZN90752.1 - 2.6e-06 27.5 0.0 7.8e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Astro_capsid_p PF12226.8 KZN90752.1 - 4.6 6.3 7.8 7.7 5.6 7.8 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein M16C_assoc PF08367.11 KZN90752.1 - 9.1 5.3 7.9 26 3.8 0.0 2.8 3 0 0 3 3 3 0 Peptidase M16C associated Ribosomal_L34 PF00468.17 KZN90753.1 - 8.2e-13 48.1 12.5 1.8e-12 47.0 12.5 1.6 1 0 0 1 1 1 1 Ribosomal protein L34 DUF4667 PF15700.5 KZN90753.1 - 0.13 12.3 4.9 0.16 12.0 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) RNA_polI_A14 PF08203.11 KZN90754.1 - 0.022 15.5 0.3 0.076 13.7 0.0 1.9 2 1 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 Peptidase_M48_N PF16491.5 KZN90755.1 - 1.4e-65 220.7 6.9 1.4e-65 220.7 6.9 1.7 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KZN90755.1 - 9.7e-46 156.0 0.0 1.9e-45 155.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 DUF4538 PF15061.6 KZN90755.1 - 0.067 12.9 0.8 0.16 11.7 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) eIF2_C PF09173.11 KZN90756.1 - 8.5e-35 118.9 0.4 1.6e-34 118.0 0.4 1.5 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.25 KZN90756.1 - 9.1e-13 48.4 0.2 2e-12 47.3 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU PF00009.27 KZN90756.1 - 7.9e-11 41.9 0.1 1.1e-10 41.4 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KZN90756.1 - 0.058 13.3 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1_Xtn PF16897.5 KZN90756.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain WD40 PF00400.32 KZN90757.1 - 9.2e-10 39.0 0.0 0.16 12.9 0.0 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat Myb_DNA-bind_6 PF13921.6 KZN90758.1 - 3.6e-16 59.2 0.1 3.6e-16 59.2 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain HSA PF07529.13 KZN90758.1 - 1.1e-14 54.5 0.2 1.1e-14 54.5 0.2 4.0 4 0 0 4 4 4 1 HSA Myb_DNA-binding PF00249.31 KZN90758.1 - 0.0001 22.4 2.7 0.001 19.2 0.2 3.1 3 0 0 3 3 3 1 Myb-like DNA-binding domain DUF4419 PF14388.6 KZN90759.1 - 8.2e-106 353.8 0.0 9.5e-106 353.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) RTA1 PF04479.13 KZN90760.1 - 1.7e-60 204.2 3.2 2.5e-60 203.6 3.2 1.2 1 0 0 1 1 1 1 RTA1 like protein Ion_trans PF00520.31 KZN90760.1 - 0.57 9.4 8.5 0.13 11.4 4.2 1.9 2 0 0 2 2 2 0 Ion transport protein G-patch_2 PF12656.7 KZN90761.1 - 2.2e-24 85.3 0.2 2.2e-24 85.3 0.2 3.1 3 0 0 3 3 3 1 G-patch domain G-patch PF01585.23 KZN90761.1 - 0.0065 16.3 0.2 0.017 15.0 0.2 1.7 1 0 0 1 1 1 1 G-patch domain WD40 PF00400.32 KZN90762.1 - 7.4e-55 181.7 16.8 4.2e-07 30.6 0.0 13.9 12 2 0 12 12 12 9 WD domain, G-beta repeat Utp13 PF08625.11 KZN90762.1 - 2.7e-49 166.7 0.1 4.4e-49 166.1 0.1 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 KZN90762.1 - 1.8e-12 47.4 0.9 0.12 12.6 0.0 7.7 6 2 3 9 9 9 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KZN90762.1 - 0.00056 19.0 0.2 0.35 9.8 0.0 4.3 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KZN90762.1 - 0.0015 17.3 0.6 3.5 6.3 0.1 4.4 5 1 0 5 5 5 1 Nup133 N terminal like Nup160 PF11715.8 KZN90762.1 - 0.03 13.0 10.7 6.6 5.2 1.3 5.5 4 3 2 6 6 6 0 Nucleoporin Nup120/160 Frtz PF11768.8 KZN90762.1 - 0.096 11.0 0.0 0.34 9.2 0.0 1.8 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF1699 PF08004.11 KZN90762.1 - 0.21 11.3 0.0 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) VEFS-Box PF09733.9 KZN90762.1 - 0.22 11.3 0.9 3.3 7.5 0.0 2.4 2 0 0 2 2 2 0 VEFS-Box of polycomb protein Proteasome PF00227.26 KZN90764.1 - 1.3e-37 129.1 0.0 2e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit UCH PF00443.29 KZN90764.1 - 2.7e-20 72.9 0.0 9e-20 71.2 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KZN90764.1 - 2.9e-12 46.7 0.1 6.8e-12 45.5 0.1 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein WD40 PF00400.32 KZN90765.1 - 1.5e-19 69.9 9.2 1.5e-05 25.6 0.2 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN90765.1 - 0.015 15.6 0.0 0.043 14.1 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Astro_capsid_p PF12226.8 KZN90765.1 - 1.6 7.8 4.5 2.4 7.2 4.5 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein zf-C3HC4 PF00097.25 KZN90766.1 - 5.4e-09 35.8 4.4 5.4e-09 35.8 4.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KZN90766.1 - 6.6e-08 32.8 7.0 6.6e-08 32.8 7.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KZN90766.1 - 1e-07 32.0 7.1 1e-07 32.0 7.1 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KZN90766.1 - 1.7e-07 30.9 5.4 1.7e-07 30.9 5.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KZN90766.1 - 2.1e-07 30.7 4.0 2.1e-07 30.7 4.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KZN90766.1 - 1.5e-06 28.1 5.8 1.5e-06 28.1 5.8 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KZN90766.1 - 5.2e-06 26.3 5.7 5.2e-06 26.3 5.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KZN90766.1 - 0.0029 17.4 9.2 0.0048 16.7 4.9 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KZN90766.1 - 0.0071 16.6 5.3 0.0071 16.6 5.3 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KZN90766.1 - 0.0091 16.0 1.0 0.0091 16.0 1.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger IBR PF01485.21 KZN90766.1 - 0.013 15.7 4.2 7.4 6.9 0.0 2.8 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_6 PF14835.6 KZN90766.1 - 0.022 14.6 4.0 0.022 14.6 4.0 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DZR PF12773.7 KZN90766.1 - 0.036 14.1 10.8 1.1 9.4 0.2 3.1 2 1 1 3 3 3 0 Double zinc ribbon CHCH PF06747.13 KZN90767.1 - 5.4e-05 23.2 8.1 9.4e-05 22.4 8.1 1.4 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 KZN90767.1 - 7.8e-05 22.8 1.6 0.00011 22.3 1.6 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Pet191_N PF10203.9 KZN90767.1 - 0.061 13.6 5.9 0.17 12.2 5.1 1.8 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Meis_PKNOX_N PF16493.5 KZN90767.1 - 0.71 10.2 3.4 7.9 6.9 0.1 2.2 1 1 1 2 2 2 0 N-terminal of Homeobox Meis and PKNOX1 NatB_MDM20 PF09797.9 KZN90768.1 - 3.6e-86 289.5 0.0 6.7e-86 288.6 0.0 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit Ribosomal_L36e PF01158.18 KZN90768.1 - 4.3e-34 116.6 5.0 4.3e-34 116.6 5.0 2.4 2 0 0 2 2 2 1 Ribosomal protein L36e TPR_19 PF14559.6 KZN90768.1 - 0.00047 20.6 1.8 0.029 14.9 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TUG-UBL1 PF11470.8 KZN90769.1 - 2.4e-24 85.3 0.1 5.6e-24 84.1 0.1 1.7 1 0 0 1 1 1 1 TUG ubiquitin-like domain UBX PF00789.20 KZN90769.1 - 0.011 15.9 0.0 0.047 13.9 0.0 2.2 2 0 0 2 2 2 0 UBX domain Proteasome PF00227.26 KZN90770.1 - 8.3e-42 142.8 0.0 9.6e-42 142.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit EHN PF06441.12 KZN90771.1 - 1.2e-32 112.5 0.6 4.8e-31 107.3 0.1 2.3 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KZN90771.1 - 1.5e-09 37.9 0.3 0.00044 20.0 0.1 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KZN90771.1 - 0.013 16.1 0.3 0.029 15.0 0.1 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family RuvC PF02075.17 KZN90771.1 - 0.18 11.7 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC T_cell_tran_alt PF15128.6 KZN90772.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 T-cell leukemia translocation-altered HATPase_c PF02518.26 KZN90773.1 - 1.2e-16 61.1 0.0 2.4e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KZN90773.1 - 2e-16 60.1 0.1 8.8e-05 22.6 0.1 3.5 3 0 0 3 3 3 3 Response regulator receiver domain HisKA PF00512.25 KZN90773.1 - 0.00022 21.2 0.0 0.00076 19.5 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain EMP24_GP25L PF01105.24 KZN90774.1 - 2e-51 174.5 0.3 2.3e-51 174.3 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4271 PF14093.6 KZN90774.1 - 0.14 12.0 1.7 8.4 6.2 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) SANT_DAMP1_like PF16282.5 KZN90775.1 - 3.6e-30 104.0 2.5 6.6e-30 103.1 2.5 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 KZN90775.1 - 6.6e-05 22.9 12.6 0.0035 17.3 11.9 3.0 1 1 1 2 2 2 1 DNA methyltransferase 1-associated protein 1 (DMAP1) DUF1704 PF08014.11 KZN90775.1 - 0.026 13.6 0.3 0.053 12.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) DUF1388 PF07142.12 KZN90776.1 - 2e-05 24.4 9.6 6.5e-05 22.8 9.6 1.8 1 0 0 1 1 1 1 Repeat of unknown function (DUF1388) TAL_FSA PF00923.19 KZN90777.1 - 1.4e-35 123.1 2.6 1.6e-35 122.8 2.6 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase DUF2027 PF09640.10 KZN90777.1 - 0.053 13.1 0.2 0.47 10.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2027) DUF3199 PF11436.8 KZN90777.1 - 0.067 13.2 0.4 0.19 11.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3199) DUF5060 PF16586.5 KZN90777.1 - 0.11 12.9 0.0 0.3 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5060) MFS_1 PF07690.16 KZN90778.1 - 3.9e-25 88.5 37.7 1.7e-24 86.4 26.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN90778.1 - 3.1e-08 32.9 12.6 7.9e-08 31.6 12.6 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter UL42 PF17638.2 KZN90778.1 - 0.048 13.6 0.6 0.13 12.3 0.6 1.7 1 0 0 1 1 1 0 HCMV UL42 Gly_transf_sug PF04488.15 KZN90779.1 - 4.9e-09 36.7 0.0 9.2e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KZN90779.1 - 0.052 12.9 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Glyco_hydro_72 PF03198.14 KZN90780.1 - 1.6e-89 300.3 5.7 2.3e-89 299.8 5.7 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KZN90780.1 - 4.9e-26 91.2 6.6 1.3e-25 89.9 6.6 1.8 1 0 0 1 1 1 1 X8 domain DUF2164 PF09932.9 KZN90780.1 - 0.18 11.9 0.2 0.33 11.0 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2164) zf-met2 PF12907.7 KZN90781.1 - 3.6e-18 65.4 0.7 5.9e-18 64.7 0.7 1.4 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 KZN90781.1 - 9e-07 29.7 12.4 1.5e-06 29.0 12.4 1.3 1 0 0 1 1 1 1 4F5 protein family adh_short_C2 PF13561.6 KZN90782.1 - 5.2e-47 160.4 0.0 1.6e-46 158.7 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN90782.1 - 1.7e-26 92.9 0.0 4.7e-26 91.4 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN90782.1 - 1.4e-06 28.3 0.1 3.2e-06 27.2 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KZN90782.1 - 0.00085 18.9 0.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Meth_synt_2 PF01717.18 KZN90783.1 - 3.3e-141 470.3 0.0 2.1e-137 457.7 0.0 2.4 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KZN90783.1 - 5.1e-119 397.4 0.0 9.8e-113 376.8 0.0 2.9 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain SHOCT PF09851.9 KZN90783.1 - 0.26 11.1 1.1 0.48 10.2 0.1 2.1 2 0 0 2 2 2 0 Short C-terminal domain Abhydrolase_1 PF00561.20 KZN90784.1 - 2.8e-28 99.3 0.0 5.7e-28 98.2 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KZN90784.1 - 2e-13 50.2 0.0 6.9e-13 48.4 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KZN90784.1 - 1.3e-08 35.7 0.6 1.9e-08 35.2 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KZN90784.1 - 0.0022 18.1 0.0 0.011 15.8 0.0 2.0 2 0 0 2 2 2 1 TAP-like protein Peptidase_S28 PF05577.12 KZN90784.1 - 0.031 13.1 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Esterase PF00756.20 KZN90784.1 - 0.066 12.8 0.1 0.15 11.7 0.1 1.5 1 1 0 1 1 1 0 Putative esterase Peptidase_S10 PF00450.22 KZN90785.1 - 1.8e-71 241.8 0.0 4.9e-71 240.3 0.0 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase Tcp11 PF05794.13 KZN90786.1 - 2.8e-116 389.2 0.1 3.4e-116 388.9 0.1 1.0 1 0 0 1 1 1 1 T-complex protein 11 Peptidase_M75 PF09375.10 KZN90786.1 - 0.014 14.9 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Imelysin TFIIA PF03153.13 KZN90787.1 - 3.7 7.4 7.5 4.5 7.2 7.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CTP_transf_like PF01467.26 KZN90788.1 - 0.00011 22.4 0.0 0.00044 20.5 0.0 1.9 2 0 0 2 2 2 1 Cytidylyltransferase-like Aim19 PF10315.9 KZN90789.1 - 0.0014 18.9 0.1 0.0019 18.5 0.1 1.3 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 DUF4536 PF15055.6 KZN90789.1 - 0.0019 18.4 0.8 0.0037 17.5 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4536) DUF1977 PF09320.11 KZN90790.1 - 6.2e-31 106.8 0.0 1.4e-30 105.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 KZN90790.1 - 5.2e-22 77.7 1.8 6.1e-22 77.5 0.7 1.7 2 0 0 2 2 2 1 DnaJ domain Phage_tail_S PF05069.13 KZN90790.1 - 0.1 12.4 0.3 0.25 11.2 0.3 1.5 1 0 0 1 1 1 0 Phage virion morphogenesis family Ufd2P_core PF10408.9 KZN90791.1 - 4.1e-219 729.3 12.6 5e-219 729.0 12.6 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KZN90791.1 - 1.7e-25 89.0 0.5 4.7e-25 87.6 0.5 1.9 1 0 0 1 1 1 1 U-box domain Peptidase_S41_N PF11918.8 KZN90791.1 - 0.21 11.8 2.8 4.8 7.4 0.0 3.7 4 0 0 4 4 4 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP Steroid_dh PF02544.16 KZN90792.1 - 1.3e-15 57.7 0.4 2e-06 27.9 0.1 3.4 3 1 0 3 3 3 3 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KZN90792.1 - 0.0051 16.4 0.2 0.013 15.0 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) DUF21 PF01595.20 KZN90792.1 - 5.5 6.7 6.4 40 3.9 0.0 2.9 3 0 0 3 3 3 0 Cyclin M transmembrane N-terminal domain Tyrosinase PF00264.20 KZN90794.1 - 1.5e-55 188.9 0.2 2.1e-55 188.4 0.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Metallophos PF00149.28 KZN90795.1 - 5.5e-13 49.9 2.0 7.9e-13 49.4 2.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Cofilin_ADF PF00241.20 KZN90796.1 - 2.1e-26 92.1 0.1 2.3e-26 92.0 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SOG2 PF10428.9 KZN90797.1 - 3e-87 294.0 0.0 2.9e-50 171.9 0.0 4.7 4 1 1 5 5 5 2 RAM signalling pathway protein LRR_4 PF12799.7 KZN90797.1 - 6e-12 45.6 3.4 2e-05 24.8 1.2 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KZN90797.1 - 8.7e-12 44.6 5.0 5.9e-10 38.8 2.9 2.8 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 KZN90797.1 - 0.0032 17.8 2.1 19 6.3 0.2 4.8 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_9 PF14580.6 KZN90797.1 - 0.021 14.3 0.3 0.043 13.3 0.3 1.5 1 0 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 KZN90797.1 - 0.54 10.5 6.1 15 5.9 0.1 3.8 4 0 0 4 4 4 0 Leucine Rich repeat MRP-S25 PF13741.6 KZN90798.1 - 4.3e-84 281.7 2.2 4.9e-84 281.5 2.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 PPR_2 PF13041.6 KZN90799.1 - 7.9e-11 42.0 0.1 0.00069 19.8 0.0 3.9 3 0 0 3 3 3 2 PPR repeat family PPR PF01535.20 KZN90799.1 - 3e-05 24.0 0.3 0.012 15.8 0.0 4.0 4 0 0 4 4 4 1 PPR repeat TPR_14 PF13428.6 KZN90799.1 - 0.017 15.9 0.4 2.3 9.3 0.0 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat PPR_long PF17177.4 KZN90799.1 - 0.022 14.2 0.0 0.064 12.6 0.0 1.7 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 KZN90799.1 - 0.064 13.4 0.0 6.3 7.0 0.0 3.1 3 0 0 3 3 3 0 Pentatricopeptide repeat domain DUF1722 PF08349.11 KZN90799.1 - 0.11 12.8 0.0 0.7 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Helicase_C PF00271.31 KZN90800.1 - 2.4e-16 60.1 0.0 9.6e-12 45.2 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.29 KZN90800.1 - 1e-15 58.0 0.0 1.7e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KZN90800.1 - 1.9e-07 31.7 0.8 1.9e-07 31.7 0.8 1.9 2 0 0 2 2 2 1 RecQ zinc-binding KH_1 PF00013.29 KZN90801.1 - 3.4e-08 33.2 0.0 0.00016 21.4 0.0 2.7 2 0 0 2 2 2 2 KH domain ALS_ss_C PF10369.9 KZN90802.1 - 2.2e-15 56.6 0.0 3.9e-14 52.6 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 KZN90802.1 - 7.5e-13 48.0 0.1 1.3e-12 47.2 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 KZN90802.1 - 6.1e-08 32.4 0.0 1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 KZN90802.1 - 0.021 14.8 0.1 4.1 7.5 0.0 2.5 2 0 0 2 2 2 0 ACT domain LEA_2 PF03168.13 KZN90803.1 - 5e-05 23.8 0.2 0.0079 16.7 0.1 3.4 3 0 0 3 3 3 1 Late embryogenesis abundant protein DUF3712 PF12505.8 KZN90803.1 - 6.1e-05 23.3 0.6 0.00079 19.7 0.6 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) OTCace PF00185.24 KZN90804.1 - 1.9e-45 154.8 0.0 2.9e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 KZN90804.1 - 2.4e-45 154.2 0.1 3.9e-45 153.5 0.1 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Bac_rhamnosid PF05592.11 KZN90804.1 - 0.075 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain FAD_binding_3 PF01494.19 KZN90805.1 - 1.2e-14 54.4 0.1 5e-14 52.3 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 KZN90805.1 - 0.01 14.9 0.0 0.099 11.7 0.0 2.1 1 1 0 1 1 1 0 Squalene epoxidase Pyr_redox_2 PF07992.14 KZN90805.1 - 0.013 14.7 1.0 0.11 11.7 0.5 2.1 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KZN90805.1 - 0.02 13.8 0.1 0.15 10.8 0.0 2.0 1 1 1 2 2 2 0 Tryptophan halogenase NAD_binding_8 PF13450.6 KZN90805.1 - 0.031 14.5 0.5 0.09 13.0 0.5 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KZN90805.1 - 0.63 9.6 2.3 25 4.3 0.0 2.2 1 1 0 2 2 2 0 FAD dependent oxidoreductase DUF3984 PF13136.6 KZN90806.1 - 1.1e-109 366.9 17.7 1.4e-109 366.6 17.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) Cut8 PF08559.10 KZN90807.1 - 1.5e-80 270.3 0.0 1.9e-80 270.0 0.0 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein rRNA_proc-arch PF13234.6 KZN90808.1 - 9.5e-89 297.9 0.1 2.1e-88 296.8 0.1 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 KZN90808.1 - 2.4e-56 189.9 1.4 6.7e-56 188.5 1.4 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 KZN90808.1 - 4e-18 65.8 0.2 1.3e-17 64.1 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KZN90808.1 - 1.3e-06 28.7 0.0 5.6e-06 26.7 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KZN90808.1 - 5.3e-05 23.3 0.0 0.00018 21.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KZN90808.1 - 0.012 14.7 0.0 0.029 13.4 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.6 KZN90808.1 - 0.053 13.8 0.1 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KZN90808.1 - 0.074 13.0 0.4 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea COX7C PF02935.16 KZN90809.1 - 2.2e-22 79.1 4.7 5e-22 77.9 4.2 1.7 2 0 0 2 2 2 1 Cytochrome c oxidase subunit VIIc IKI3 PF04762.12 KZN90810.1 - 0 1040.1 0.0 0 1039.8 0.0 1.1 1 0 0 1 1 1 1 IKI3 family UME PF08064.13 KZN90810.1 - 0.17 11.8 0.3 7.8 6.5 0.0 3.1 3 0 0 3 3 3 0 UME (NUC010) domain MDD_C PF18376.1 KZN90811.1 - 4.4e-67 225.5 0.0 7e-67 224.8 0.0 1.3 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KZN90811.1 - 7.8e-10 38.9 0.4 2.3e-09 37.4 0.4 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain Cyto_heme_lyase PF01265.17 KZN90812.1 - 2.5e-39 135.6 4.6 7.4e-34 117.7 0.2 3.3 2 1 0 2 2 2 2 Cytochrome c/c1 heme lyase Syntaxin_2 PF14523.6 KZN90813.1 - 4.7e-26 91.1 7.6 6.6e-26 90.6 2.4 2.5 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KZN90813.1 - 5.8e-12 45.4 2.0 5.8e-12 45.4 2.0 1.8 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KZN90813.1 - 1.1e-05 25.3 13.0 7.6e-05 22.5 13.0 2.2 1 1 0 1 1 1 1 Syntaxin Synaptobrevin PF00957.21 KZN90813.1 - 0.0053 16.5 2.2 0.012 15.4 0.6 2.3 2 0 0 2 2 2 1 Synaptobrevin Nre_C PF04895.12 KZN90813.1 - 0.04 13.8 0.4 0.16 11.9 0.1 2.1 2 0 0 2 2 2 0 Archaeal Nre, C-terminal DUF883 PF05957.13 KZN90813.1 - 0.17 12.5 0.1 0.17 12.5 0.1 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) AIF-MLS PF14962.6 KZN90813.1 - 0.17 11.8 1.1 0.31 11.0 1.1 1.4 1 0 0 1 1 1 0 Mitochondria Localisation Sequence T3SSipB PF16535.5 KZN90813.1 - 0.19 12.2 7.9 0.37 11.3 3.4 2.7 3 0 0 3 3 3 0 Type III cell invasion protein SipB Prominin PF05478.11 KZN90813.1 - 0.37 8.7 6.4 0.78 7.6 6.4 1.6 1 1 0 1 1 1 0 Prominin DUF1664 PF07889.12 KZN90813.1 - 1.5 8.8 5.2 17 5.4 1.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) LPP PF04728.13 KZN90813.1 - 4.5 7.7 6.5 7 7.1 0.1 3.5 3 1 0 3 3 3 0 Lipoprotein leucine-zipper DUF5345 PF17280.2 KZN90813.1 - 5.4 7.1 7.4 1.8 8.6 0.1 3.1 3 1 0 3 3 3 0 Family of unknown function (DUF5345) Ndc1_Nup PF09531.10 KZN90814.1 - 1.6e-192 641.5 5.6 1.8e-192 641.3 5.6 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Vfa1 PF08432.10 KZN90815.1 - 5.6e-61 206.0 16.8 6.4e-61 205.8 16.8 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 KZN90815.1 - 0.014 13.7 12.3 0.014 13.8 12.3 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 KZN90815.1 - 0.057 13.3 10.8 0.081 12.7 10.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4228 PF14009.6 KZN90815.1 - 0.063 13.7 3.4 0.083 13.3 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DUF913 PF06025.12 KZN90815.1 - 0.48 9.3 4.1 0.5 9.3 4.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.13 KZN90815.1 - 2 7.1 15.5 2.4 6.8 15.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TAF4 PF05236.14 KZN90815.1 - 2.6 7.7 17.4 3.8 7.2 17.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family TFIIF_alpha PF05793.12 KZN90815.1 - 2.9 6.4 30.7 3.9 6.0 30.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Presenilin PF01080.17 KZN90815.1 - 3.2 6.4 11.1 4 6.1 11.1 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 KZN90815.1 - 3.7 7.5 6.2 4.3 7.3 6.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PPL5 PF18168.1 KZN90815.1 - 3.8 6.7 12.4 4.8 6.4 12.4 1.1 1 0 0 1 1 1 0 Prim-pol family 5 SAPS PF04499.15 KZN90815.1 - 4.2 6.0 11.9 4.9 5.8 11.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ATP11 PF06644.11 KZN90815.1 - 4.3 7.1 12.6 5.3 6.7 12.6 1.2 1 0 0 1 1 1 0 ATP11 protein SLC12 PF03522.15 KZN90815.1 - 5.6 5.9 12.0 6.4 5.7 12.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF2151 PF10221.9 KZN90815.1 - 5.8 5.4 12.7 6.6 5.2 12.7 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator DUF2252 PF10009.9 KZN90815.1 - 6.9 5.6 9.2 8.9 5.3 9.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Atrophin-1 PF03154.15 KZN90815.1 - 8.9 4.5 14.2 11 4.1 14.2 1.2 1 0 0 1 1 1 0 Atrophin-1 family DSPc PF00782.20 KZN90816.1 - 3.3e-24 85.2 0.0 4.6e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KZN90816.1 - 0.0016 18.7 0.0 0.0031 17.8 0.0 1.5 1 0 0 1 1 1 1 Rit1 DUSP-like domain zf-C2H2 PF00096.26 KZN90817.1 - 0.016 15.6 22.7 0.048 14.1 1.8 4.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-FCS PF06467.14 KZN90817.1 - 0.024 14.6 1.9 3.2 7.8 0.1 2.8 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-CHCC PF10276.9 KZN90817.1 - 0.42 10.7 3.7 7.3 6.7 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger domain zf-C2H2_jaz PF12171.8 KZN90817.1 - 1.8 9.0 14.5 1 9.7 3.8 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KZN90817.1 - 5.6 8.1 22.2 8.5 7.5 2.5 5.1 4 0 0 4 4 4 0 C2H2-type zinc finger 4HBT PF03061.22 KZN90818.1 - 0.049 14.0 0.0 8.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Thioesterase superfamily FMN_dh PF01070.18 KZN90819.1 - 6.4e-107 357.6 0.0 7.3e-107 357.4 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KZN90819.1 - 8.8e-05 21.7 0.6 0.00016 20.8 0.6 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KZN90819.1 - 0.0021 17.3 0.1 0.0031 16.7 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KZN90819.1 - 0.0027 17.2 0.4 0.025 14.0 0.2 2.1 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 KZN90819.1 - 0.085 12.2 0.4 1.6 7.9 0.1 2.2 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG Asp PF00026.23 KZN90820.1 - 1.8e-70 237.8 0.8 2.5e-70 237.4 0.8 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KZN90820.1 - 1.1e-10 42.0 3.2 3.3e-05 24.2 1.2 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KZN90820.1 - 0.00041 20.9 0.0 0.37 11.5 0.0 3.1 3 0 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.6 KZN90820.1 - 0.002 17.9 0.0 0.0053 16.6 0.0 1.7 1 1 1 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KZN90820.1 - 0.08 13.5 0.0 4.7 7.8 0.0 2.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF5349 PF17298.2 KZN90820.1 - 0.12 12.2 12.3 0.27 10.9 12.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5349) CHASE PF03924.13 KZN90820.1 - 0.15 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 CHASE domain FMN_dh PF01070.18 KZN90822.1 - 2.3e-114 382.1 0.0 2.8e-114 381.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KZN90822.1 - 1.4e-18 66.8 0.0 2.9e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KZN90822.1 - 8.6e-05 21.8 0.1 0.00017 20.9 0.1 1.4 1 1 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KZN90822.1 - 0.005 15.9 0.2 0.013 14.5 0.1 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KZN90822.1 - 0.011 15.1 0.1 0.12 11.8 0.1 2.0 1 1 1 2 2 2 0 Nitronate monooxygenase ThiG PF05690.14 KZN90822.1 - 0.014 14.7 0.0 2.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Nup54_C PF18437.1 KZN90822.1 - 0.18 11.7 0.1 0.34 10.8 0.1 1.4 1 0 0 1 1 1 0 Nup54 C-terminal interacting domain TatD_DNase PF01026.21 KZN90823.1 - 3.9e-50 170.6 0.0 4.7e-50 170.3 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Y_phosphatase2 PF03162.13 KZN90824.1 - 4.2e-13 49.2 0.0 4.5e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF2620 PF10941.8 KZN90825.1 - 0.17 12.0 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF2620 Peptidase_C13 PF01650.18 KZN90826.1 - 2.5e-06 27.2 0.0 3.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family Aa_trans PF01490.18 KZN90827.1 - 8.5e-73 245.4 25.5 9.9e-73 245.2 25.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Rad52_Rad22 PF04098.15 KZN90829.1 - 4.7e-61 205.2 0.1 6.3e-61 204.8 0.1 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein UBA PF00627.31 KZN90830.1 - 7.6e-05 22.5 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain UBX PF00789.20 KZN90830.1 - 0.0024 18.1 0.5 0.005 17.0 0.0 1.9 2 0 0 2 2 2 1 UBX domain Draxin PF15550.6 KZN90830.1 - 0.016 15.1 14.5 0.02 14.8 14.5 1.2 1 0 0 1 1 1 0 Draxin DUF5401 PF17380.2 KZN90830.1 - 0.036 12.2 20.8 0.045 11.8 20.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5401) CDC27 PF09507.10 KZN90830.1 - 1.3 8.4 28.2 1.5 8.2 28.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF4551 PF15087.6 KZN90830.1 - 3 6.6 12.2 3.6 6.3 12.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) V_ATPase_I PF01496.19 KZN90830.1 - 3.1 5.6 8.4 3.3 5.5 8.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Hid1 PF12722.7 KZN90830.1 - 6.8 4.7 11.6 7 4.6 11.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 KZN90830.1 - 8.6 4.5 19.7 12 4.1 19.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Motile_Sperm PF00635.26 KZN90831.1 - 3e-26 91.4 0.2 5.8e-26 90.5 0.2 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ATG16 PF08614.11 KZN90831.1 - 0.016 15.5 1.2 0.021 15.1 1.2 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) ASH PF15780.5 KZN90831.1 - 0.017 15.3 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin FA_desaturase PF00487.24 KZN90832.1 - 1e-26 94.4 12.7 1.3e-26 94.0 12.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 KZN90832.1 - 4.1e-18 64.6 0.2 7.5e-18 63.7 0.2 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Peptidase_M24 PF00557.24 KZN90833.1 - 3.4e-43 147.8 0.1 4.4e-43 147.4 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AP3D1 PF06375.11 KZN90833.1 - 0.012 15.9 4.1 0.023 14.9 4.1 1.5 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 LZ_Tnp_IS66 PF13007.7 KZN90833.1 - 0.4 11.5 4.1 0.9 10.4 4.1 1.5 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain CCDC106 PF15794.5 KZN90833.1 - 0.79 9.4 3.9 1.4 8.6 3.9 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Ank_2 PF12796.7 KZN90834.1 - 1.2e-15 57.8 0.0 0.003 18.1 0.1 4.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN90834.1 - 4.3e-14 52.7 5.7 0.14 12.7 0.0 7.2 3 2 5 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN90834.1 - 9.4e-08 31.8 6.2 10 7.0 0.0 8.1 10 0 0 10 10 10 2 Ankyrin repeat Ank PF00023.30 KZN90834.1 - 9.7e-06 25.8 4.3 9.1 6.9 0.0 6.8 8 0 0 8 8 8 1 Ankyrin repeat Git3 PF11710.8 KZN90835.1 - 9.6e-25 87.6 10.1 9.6e-25 87.6 10.1 2.1 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KZN90835.1 - 9.6e-12 44.8 0.4 5.2e-11 42.4 0.0 2.4 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Ank_2 PF12796.7 KZN90836.1 - 3e-27 95.0 3.1 4.5e-10 40.0 0.1 4.7 4 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN90836.1 - 2.5e-18 66.2 4.4 4.7e-07 30.2 0.0 6.8 7 1 1 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN90836.1 - 8.3e-15 53.4 10.1 0.0058 17.0 0.0 8.1 9 0 0 9 9 9 5 Ankyrin repeat Ank PF00023.30 KZN90836.1 - 1.4e-10 41.2 11.4 0.033 14.7 0.0 6.4 6 1 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KZN90836.1 - 2.2e-07 31.0 9.6 0.12 12.8 0.9 6.0 3 1 3 6 6 6 5 Ankyrin repeats (many copies) F-box-like PF12937.7 KZN90836.1 - 7.8e-05 22.5 0.0 0.00019 21.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN90836.1 - 0.00017 21.4 0.7 0.00034 20.4 0.1 1.8 2 0 0 2 2 2 1 F-box domain DnaJ PF00226.31 KZN90837.1 - 8.3e-13 48.3 0.1 1.4e-12 47.5 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Porin_3 PF01459.22 KZN90838.1 - 1.4e-70 237.9 5.0 5.7e-58 196.5 2.4 2.0 2 0 0 2 2 2 2 Eukaryotic porin Asn_synthase PF00733.21 KZN90839.1 - 1.6e-95 320.8 0.5 7.5e-56 190.3 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KZN90839.1 - 5.6e-39 132.8 0.0 9.6e-39 132.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KZN90839.1 - 9.1e-29 100.4 0.0 2e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KZN90839.1 - 1.9e-06 27.5 0.0 3.8e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KZN90839.1 - 0.0046 16.1 0.0 0.0071 15.5 0.0 1.5 1 1 0 1 1 1 1 NAD synthase UQ_con PF00179.26 KZN90840.1 - 2.4e-44 150.4 0.0 2.8e-44 150.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme fn3_4 PF16794.5 KZN90841.1 - 0.065 13.2 0.0 0.29 11.1 0.0 2.0 2 0 0 2 2 2 0 Fibronectin-III type domain PBP1_TM PF14812.6 KZN90841.1 - 0.56 10.6 3.8 9.8 6.6 0.1 3.0 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal G-patch PF01585.23 KZN90842.1 - 2.4e-09 36.9 1.7 6e-09 35.6 1.7 1.7 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 KZN90842.1 - 0.015 15.1 0.0 0.038 13.8 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 KZN90842.1 - 0.021 14.9 0.5 0.021 14.9 0.5 2.2 2 0 0 2 2 2 0 G-patch domain Mito_carr PF00153.27 KZN90843.1 - 3.4e-65 216.0 3.0 2.3e-22 78.7 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein UCR_14kD PF02271.16 KZN90844.1 - 8.3e-44 147.6 0.1 9.6e-44 147.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Ferritin PF00210.24 KZN90844.1 - 0.019 14.9 0.0 0.054 13.4 0.0 1.8 1 1 0 1 1 1 0 Ferritin-like domain HhH-GPD PF00730.25 KZN90845.1 - 5.7e-14 52.5 0.0 9.6e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein IGR PF09597.10 KZN90845.1 - 0.083 13.0 0.0 0.82 9.8 0.0 2.3 2 0 0 2 2 2 0 IGR protein motif RuvB_C PF05491.13 KZN90845.1 - 0.18 11.7 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 RuvB C-terminal winged helix domain Ecm33 PF12454.8 KZN90846.1 - 5.2e-14 52.1 0.5 5.2e-14 52.1 0.5 2.3 2 0 0 2 2 2 1 GPI-anchored cell wall organization protein LRR_5 PF13306.6 KZN90846.1 - 2.2e-06 27.7 0.1 0.11 12.5 0.0 2.5 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) Recep_L_domain PF01030.24 KZN90846.1 - 6.1e-06 26.3 0.4 0.48 10.6 0.2 4.6 1 1 4 5 5 5 2 Receptor L domain VPS28 PF03997.12 KZN90847.1 - 0.094 12.4 1.7 0.14 11.8 1.7 1.2 1 0 0 1 1 1 0 VPS28 protein DivIC PF04977.15 KZN90847.1 - 2.2 8.1 5.3 4.9 7.0 5.3 1.6 1 0 0 1 1 1 0 Septum formation initiator Anp1 PF03452.14 KZN90848.1 - 5e-107 357.2 0.0 6.1e-107 356.9 0.0 1.1 1 0 0 1 1 1 1 Anp1 YCII PF03795.14 KZN90849.1 - 2.3e-09 37.5 0.0 3.1e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain NifU_N PF01592.16 KZN90850.1 - 7.3e-54 181.4 0.1 9.4e-54 181.0 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain ABC1 PF03109.16 KZN90851.1 - 5.8e-34 116.8 0.0 1.1e-33 115.9 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Alpha_E3_glycop PF01563.16 KZN90851.1 - 0.091 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Alphavirus E3 glycoprotein RIO1 PF01163.22 KZN90851.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 KZN90852.1 - 5.3e-73 245.6 0.0 1.6e-72 244.1 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN90852.1 - 1.1e-50 172.4 0.0 2.2e-50 171.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KZN90852.1 - 0.0021 16.9 0.0 0.0038 16.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KZN90852.1 - 0.023 14.0 0.0 0.38 10.0 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Exo70 PF03081.15 KZN90852.1 - 0.57 9.2 4.9 4 6.4 0.5 3.0 3 0 0 3 3 3 0 Exo70 exocyst complex subunit Adaptin_N PF01602.20 KZN90852.1 - 1 7.8 7.5 4.4 5.7 5.3 2.5 2 1 0 2 2 2 0 Adaptin N terminal region Mur_ligase_M PF08245.12 KZN90853.1 - 9.5e-07 29.0 0.0 1.8e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Mur ligase middle domain PRK PF00485.18 KZN90855.1 - 0.00062 19.6 0.0 0.00088 19.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 KZN90855.1 - 0.016 14.4 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 KZN90855.1 - 0.042 13.1 0.1 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 KZN90855.1 - 0.051 13.7 0.4 4.9 7.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KZN90855.1 - 0.062 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 KZN90855.1 - 0.08 13.3 0.0 0.1 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KZN90855.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KZN90855.1 - 0.12 12.9 0.0 0.4 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Sacchrp_dh_C PF16653.5 KZN90856.1 - 0.069 13.2 0.4 0.084 13.0 0.4 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase C-terminal domain Plasmodium_Vir PF05795.11 KZN90856.1 - 0.35 10.3 1.6 0.39 10.1 1.6 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Ribonuc_red_lgC PF02867.15 KZN90857.1 - 4e-184 613.0 0.0 5.7e-184 612.5 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KZN90857.1 - 9.3e-23 80.0 0.9 2.8e-22 78.5 0.0 2.1 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KZN90857.1 - 2.1e-15 57.0 0.0 5.2e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 ATP cone domain Glyco_transf_25 PF01755.17 KZN90858.1 - 0.0053 16.6 0.0 0.012 15.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) DAP_epimerase PF01678.19 KZN90858.1 - 0.012 15.8 0.1 0.023 14.9 0.1 1.4 1 0 0 1 1 1 0 Diaminopimelate epimerase DPBB_1 PF03330.18 KZN90859.1 - 0.0015 18.8 0.0 0.0041 17.4 0.0 1.8 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KZN90859.1 - 0.035 14.0 0.4 0.077 12.8 0.4 1.6 1 0 0 1 1 1 0 Barwin family DUF4772 PF15997.5 KZN90859.1 - 0.084 13.5 0.2 0.084 13.5 0.2 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4772) BPL_C PF02237.17 KZN90859.1 - 0.14 12.0 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain CDC27 PF09507.10 KZN90859.1 - 8.6 5.6 10.8 12 5.2 10.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 FAA_hydrolase PF01557.18 KZN90860.1 - 3e-58 197.1 0.0 3.9e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAD_binding_3 PF01494.19 KZN90861.1 - 4.8e-16 58.9 5.4 1.4e-13 50.8 5.4 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KZN90861.1 - 8e-07 28.6 0.2 0.0017 17.6 0.1 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KZN90861.1 - 0.004 16.8 7.1 0.54 9.8 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KZN90861.1 - 0.0086 15.2 0.7 0.026 13.6 0.7 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein SE PF08491.10 KZN90861.1 - 0.066 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Squalene epoxidase FAD_binding_2 PF00890.24 KZN90861.1 - 0.075 12.1 6.4 0.13 11.3 6.4 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 KZN90861.1 - 0.11 12.7 4.8 0.32 11.3 4.8 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Eno-Rase_NADH_b PF12242.8 KZN90861.1 - 0.14 11.9 0.1 0.35 10.6 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HI0933_like PF03486.14 KZN90861.1 - 0.22 10.2 2.4 17 4.0 2.9 2.1 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 KZN90861.1 - 0.79 8.7 5.3 1.5 7.8 5.3 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KZN90861.1 - 2.1 7.6 4.2 3.2 7.0 4.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KZN90861.1 - 2.4 6.9 6.1 15 4.3 0.0 3.1 2 1 1 3 3 3 0 Tryptophan halogenase Cupin_2 PF07883.11 KZN90862.1 - 7.4e-26 89.7 0.3 4e-15 55.3 0.2 2.2 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 KZN90862.1 - 6.4e-06 26.1 0.2 0.021 14.7 0.1 2.5 2 0 0 2 2 2 2 AraC-like ligand binding domain CENP-C_C PF11699.8 KZN90862.1 - 1.1e-05 25.6 0.0 9.9e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 Mif2/CENP-C like Cupin_3 PF05899.12 KZN90862.1 - 0.0014 18.3 0.0 2.1 8.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) ARD PF03079.14 KZN90862.1 - 0.012 15.8 0.2 0.09 13.0 0.0 2.0 2 0 0 2 2 2 0 ARD/ARD' family ArsB PF02040.15 KZN90863.1 - 3.8e-09 36.4 23.8 2.1e-05 24.0 12.1 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein PMSI1 PF15322.6 KZN90864.1 - 0.013 14.9 0.2 0.02 14.4 0.2 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Fungal_trans PF04082.18 KZN90865.1 - 1.4e-25 89.8 0.0 2e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN90865.1 - 3.1e-11 43.2 5.3 5.2e-11 42.5 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Metallophos PF00149.28 KZN90866.1 - 9.6e-08 32.8 0.3 1.9e-07 31.8 0.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MFS_1 PF07690.16 KZN90867.1 - 2.3e-12 46.5 31.6 2.3e-12 46.5 31.6 3.5 2 2 1 4 4 4 2 Major Facilitator Superfamily ELFV_dehydrog PF00208.21 KZN90869.1 - 1.2e-83 280.5 4.3 1.5e-83 280.2 4.3 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KZN90869.1 - 2.9e-51 172.7 0.0 6e-51 171.7 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Med5 PF08689.10 KZN90870.1 - 6.4e-185 617.0 0.0 6.9e-184 613.6 0.0 2.2 1 1 0 1 1 1 1 Mediator complex subunit Med5 ABC2_membrane PF01061.24 KZN90871.1 - 1.4e-77 259.8 49.5 1.1e-44 152.4 15.8 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KZN90871.1 - 1.2e-37 129.5 0.0 6e-18 65.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KZN90871.1 - 2.2e-29 101.2 7.7 1.4e-27 95.4 0.0 3.5 3 0 0 3 3 3 2 CDR ABC transporter AAA_16 PF13191.6 KZN90871.1 - 5.6e-07 30.1 0.1 0.00062 20.2 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain ABC2_membrane_3 PF12698.7 KZN90871.1 - 8.7e-06 25.1 32.4 0.003 16.7 11.8 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.6 KZN90871.1 - 0.00013 21.6 0.1 0.003 17.1 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KZN90871.1 - 0.00023 21.4 0.1 0.89 9.8 0.1 2.7 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KZN90871.1 - 0.00037 20.7 0.0 0.82 9.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KZN90871.1 - 0.00065 20.3 0.0 3.4 8.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KZN90871.1 - 0.0012 18.8 0.1 0.0082 16.1 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KZN90871.1 - 0.0013 18.4 1.0 0.091 12.5 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.6 KZN90871.1 - 0.0022 18.2 0.4 0.99 9.6 0.2 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KZN90871.1 - 0.0041 16.7 0.6 1.3 8.6 0.1 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KZN90871.1 - 0.036 14.0 0.3 2.6 7.9 0.1 2.3 2 0 0 2 2 2 0 NACHT domain ABC_trans_N PF14510.6 KZN90871.1 - 0.066 13.8 0.0 0.18 12.4 0.0 1.8 1 0 0 1 1 1 0 ABC-transporter N-terminal AAA_30 PF13604.6 KZN90871.1 - 0.066 12.9 0.2 7.1 6.3 0.3 2.3 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KZN90871.1 - 0.11 12.2 0.9 9.2 6.0 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.12 KZN90871.1 - 0.14 11.4 0.0 3.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_21 PF13304.6 KZN90871.1 - 0.18 11.6 0.0 4.6 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 KZN90871.1 - 0.19 11.6 0.0 28 4.6 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain HTH_32 PF13565.6 KZN90872.1 - 7.4e-08 32.9 2.7 0.00022 21.8 0.5 2.1 1 1 1 2 2 2 2 Homeodomain-like domain HTH_29 PF13551.6 KZN90872.1 - 0.012 15.7 0.5 0.018 15.1 0.5 1.4 1 1 0 1 1 1 0 Winged helix-turn helix HTH_38 PF13936.6 KZN90872.1 - 0.077 12.8 0.1 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain RasGEF PF00617.19 KZN90873.1 - 1.6e-50 171.8 1.1 3.3e-50 170.7 1.1 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KZN90873.1 - 1.1e-15 57.8 0.0 3e-15 56.3 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 KZN90873.1 - 1.9e-06 27.6 0.0 4.3e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KZN90873.1 - 1.8e-05 24.3 0.0 3.6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain HATPase_c_3 PF13589.6 KZN90874.1 - 8.4e-19 67.8 0.0 1.7e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KZN90874.1 - 2.5e-06 27.9 0.0 5.9e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 KZN90874.1 - 2.4e-05 24.1 0.0 0.00066 19.5 0.0 2.7 2 1 0 2 2 2 1 MutL C terminal dimerisation domain p450 PF00067.22 KZN90876.1 - 7.1e-45 153.6 0.0 9.5e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PAN_4 PF14295.6 KZN90879.1 - 0.00065 19.6 1.4 0.00065 19.6 1.4 3.6 3 0 0 3 3 3 1 PAN domain PAN_3 PF08277.12 KZN90879.1 - 0.0022 17.8 1.8 0.012 15.4 0.1 2.9 2 0 0 2 2 2 1 PAN-like domain Csm1_N PF18504.1 KZN90879.1 - 0.016 15.6 7.0 0.016 15.6 7.0 2.5 1 1 2 3 3 3 0 Csm1 N-terminal domain ADIP PF11559.8 KZN90879.1 - 0.044 13.9 15.5 0.073 13.2 15.5 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Macoilin PF09726.9 KZN90879.1 - 0.047 12.3 12.3 0.052 12.1 12.3 1.2 1 0 0 1 1 1 0 Macoilin family Golgin_A5 PF09787.9 KZN90879.1 - 0.16 11.5 22.1 0.31 10.5 22.1 1.4 1 1 0 1 1 1 0 Golgin subfamily A member 5 Exonuc_VII_L PF02601.15 KZN90879.1 - 0.16 11.5 5.5 0.22 11.0 5.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4988 PF16378.5 KZN90879.1 - 0.17 11.6 0.4 0.32 10.6 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function HemX PF04375.14 KZN90879.1 - 0.28 10.4 4.7 0.43 9.8 4.7 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase FapA PF03961.13 KZN90879.1 - 0.45 9.1 6.0 0.69 8.4 6.0 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4164 PF13747.6 KZN90879.1 - 0.48 10.7 11.0 0.35 11.2 8.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Spc7 PF08317.11 KZN90879.1 - 0.56 9.0 16.0 0.91 8.3 16.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2968 PF11180.8 KZN90879.1 - 0.88 9.2 11.3 1.3 8.6 11.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) V_ATPase_I PF01496.19 KZN90879.1 - 1.4 6.8 2.8 1.6 6.6 2.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4446 PF14584.6 KZN90879.1 - 3.1 7.8 6.8 19 5.2 2.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) DUF3450 PF11932.8 KZN90879.1 - 3.5 6.9 8.9 5.6 6.2 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Ank_2 PF12796.7 KZN90880.1 - 2.6e-19 69.6 0.0 3.7e-09 37.0 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN90880.1 - 1.5e-13 50.9 0.1 3e-05 24.5 0.1 4.8 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KZN90880.1 - 2.9e-13 49.6 0.1 0.0064 16.9 0.1 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KZN90880.1 - 1e-12 48.0 0.1 7.6e-07 29.3 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN90880.1 - 8.3e-12 44.2 0.0 0.0021 18.4 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeat vWA-TerF-like PF10138.9 KZN90880.1 - 0.0027 17.9 0.0 0.0051 16.9 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus Dyp_perox PF04261.12 KZN90882.1 - 1.5e-10 40.6 0.0 1.1e-08 34.4 0.0 2.8 3 0 0 3 3 3 2 Dyp-type peroxidase family bZIP_2 PF07716.15 KZN90883.1 - 7.6e-14 51.5 12.1 2e-13 50.2 12.1 1.8 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KZN90883.1 - 0.00026 21.0 6.6 0.00053 20.0 6.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor DDRGK PF09756.9 KZN90883.1 - 0.24 10.9 11.4 0.48 10.0 11.4 1.4 1 0 0 1 1 1 0 DDRGK domain DUF5343 PF17278.2 KZN90883.1 - 3.7 7.6 9.5 0.13 12.3 1.3 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5343) TehB PF03848.14 KZN90884.1 - 0.05 13.0 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_23 PF13489.6 KZN90884.1 - 0.13 12.0 0.0 0.23 11.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.16 KZN90885.1 - 6.6e-39 133.8 41.1 6.6e-39 133.8 41.1 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN90885.1 - 1.2e-11 44.2 7.2 1.2e-11 44.2 7.2 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter Fungal_trans_2 PF11951.8 KZN90886.1 - 6e-07 28.6 0.0 7.3e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain RelB_transactiv PF16181.5 KZN90886.1 - 0.087 13.1 0.2 0.14 12.4 0.2 1.2 1 0 0 1 1 1 0 RelB transactivation domain adh_short_C2 PF13561.6 KZN90887.1 - 1.5e-44 152.3 0.0 1.8e-44 152.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN90887.1 - 1.5e-35 122.5 0.1 1.7e-35 122.3 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN90887.1 - 2.8e-10 40.4 0.1 3.2e-10 40.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KZN90887.1 - 0.07 12.6 0.2 0.17 11.3 0.2 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_8 PF13450.6 KZN90888.1 - 4.9e-16 58.7 0.0 1.4e-15 57.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KZN90888.1 - 9.1e-10 38.4 0.0 7.4e-06 25.5 0.0 3.1 3 0 0 3 3 3 3 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KZN90888.1 - 0.003 17.6 0.1 0.5 10.3 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 KZN90888.1 - 0.0046 16.6 0.1 0.022 14.4 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KZN90888.1 - 0.0089 15.3 0.0 0.3 10.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KZN90888.1 - 0.032 14.8 0.2 0.21 12.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KZN90888.1 - 0.073 12.1 0.0 0.19 10.8 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain CENP-N PF05238.13 KZN90889.1 - 3.3e-141 471.4 0.0 3.7e-141 471.2 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like Prok-RING_1 PF14446.6 KZN90890.1 - 5e-06 26.3 3.5 5e-06 26.3 3.5 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 KZN90890.1 - 5.6e-06 26.6 9.8 5.6e-06 26.6 9.8 2.3 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.8 KZN90890.1 - 0.00033 20.8 8.1 0.00033 20.8 8.1 2.2 2 1 0 2 2 2 1 FANCL C-terminal domain HypA PF01155.19 KZN90890.1 - 0.00067 19.6 2.1 0.0078 16.2 0.3 2.3 1 1 1 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA SWIM PF04434.17 KZN90890.1 - 0.0014 18.2 0.5 0.0014 18.2 0.5 1.7 2 0 0 2 2 1 1 SWIM zinc finger Rtf2 PF04641.12 KZN90890.1 - 0.029 13.7 0.5 0.04 13.3 0.5 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Zf_RING PF16744.5 KZN90890.1 - 0.034 14.3 5.4 0.068 13.3 5.4 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger PHF5 PF03660.14 KZN90890.1 - 0.058 13.6 0.9 0.058 13.6 0.9 2.1 2 0 0 2 2 2 0 PHF5-like protein Cytochrom_CIII PF02085.16 KZN90890.1 - 0.067 13.5 6.3 0.12 12.8 6.3 1.3 1 0 0 1 1 1 0 Class III cytochrome C family zf-RING_UBOX PF13445.6 KZN90890.1 - 0.1 12.6 4.9 0.33 11.0 4.9 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 KZN90890.1 - 0.24 11.5 8.8 0.045 13.8 3.6 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_9 PF13901.6 KZN90890.1 - 0.34 10.9 7.6 0.61 10.0 7.6 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon PHD PF00628.29 KZN90890.1 - 0.34 10.8 9.5 0.91 9.5 9.5 1.8 1 1 0 1 1 1 0 PHD-finger zf-RING_11 PF17123.5 KZN90890.1 - 1.3 8.9 7.6 1.8 8.4 5.6 2.2 2 0 0 2 2 2 0 RING-like zinc finger FYVE PF01363.21 KZN90890.1 - 3.9 7.7 15.8 0.097 12.8 7.4 2.2 2 0 0 2 2 2 0 FYVE zinc finger OrfB_Zn_ribbon PF07282.11 KZN90890.1 - 4.3 7.3 6.7 2.5 8.1 2.6 2.3 1 1 1 2 2 2 0 Putative transposase DNA-binding domain DUF2318 PF10080.9 KZN90890.1 - 6.4 7.0 8.0 2.7 8.2 1.4 2.8 2 1 1 3 3 3 0 Predicted membrane protein (DUF2318) zf-C3HC4_2 PF13923.6 KZN90890.1 - 9.5 6.2 15.3 0.18 11.7 6.9 2.5 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF974 PF06159.13 KZN90891.1 - 7.1e-80 268.4 0.0 8.7e-80 268.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) PhaC_N PF07167.13 KZN90891.1 - 0.015 14.9 0.2 0.21 11.2 0.0 2.4 2 1 1 3 3 3 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus DENN PF02141.21 KZN90892.1 - 3.8e-58 196.5 0.2 6.7e-58 195.7 0.2 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KZN90892.1 - 2.8e-13 50.4 0.0 8.5e-13 48.8 0.0 1.9 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KZN90892.1 - 9.3e-13 48.0 0.5 3.7e-12 46.0 0.3 2.2 2 0 0 2 2 2 1 dDENN domain C1_2 PF03107.16 KZN90892.1 - 3.1e-06 27.4 2.9 3.1e-06 27.4 2.9 1.7 2 0 0 2 2 2 1 C1 domain C1_1 PF00130.22 KZN90892.1 - 1.3e-05 24.9 7.0 2.5e-05 24.1 7.0 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SPA PF08616.10 KZN90892.1 - 0.032 14.2 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis Zn_ribbon_17 PF17120.5 KZN90892.1 - 0.19 11.4 6.7 0.36 10.5 6.7 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Zf_RING PF16744.5 KZN90892.1 - 0.25 11.5 5.4 0.55 10.4 5.4 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger PHD PF00628.29 KZN90892.1 - 2.4 8.1 13.2 0.44 10.5 8.4 2.3 2 1 1 3 3 3 0 PHD-finger DHquinase_I PF01487.15 KZN90893.1 - 6.6e-48 163.9 0.0 1.1e-47 163.2 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase FMN_bind_2 PF04299.12 KZN90894.1 - 1.8e-49 167.7 0.0 1.1e-48 165.1 0.0 1.9 1 1 0 1 1 1 1 Putative FMN-binding domain Fungal_trans PF04082.18 KZN90895.1 - 1.9e-18 66.4 0.0 3.6e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN90895.1 - 2.6e-06 27.5 16.8 5.9e-06 26.3 16.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.17 KZN90895.1 - 2.1 7.3 3.4 3.6 6.5 3.4 1.3 1 0 0 1 1 1 0 Clusterin Acyl_transf_1 PF00698.21 KZN90896.1 - 2.1e-27 96.5 0.3 5.1e-27 95.2 0.2 1.6 1 1 1 2 2 2 1 Acyl transferase domain BMC PF00936.19 KZN90896.1 - 0.1 12.6 2.0 0.25 11.3 2.0 1.7 1 0 0 1 1 1 0 BMC domain 2-Hacid_dh_C PF02826.19 KZN90897.1 - 5.9e-45 152.8 0.0 8.8e-45 152.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KZN90897.1 - 0.00023 20.9 0.0 0.00029 20.5 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ELFV_dehydrog PF00208.21 KZN90897.1 - 0.00079 19.2 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase XdhC_C PF13478.6 KZN90897.1 - 0.0084 16.6 0.0 0.028 14.9 0.0 1.7 2 0 0 2 2 2 1 XdhC Rossmann domain NAD_binding_7 PF13241.6 KZN90897.1 - 0.034 14.6 0.0 0.066 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding AdoHcyase_NAD PF00670.21 KZN90897.1 - 0.047 13.7 0.0 0.082 13.0 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox PF00070.27 KZN90897.1 - 0.13 12.9 0.0 0.22 12.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Cu_amine_oxid PF01179.20 KZN90898.1 - 1.1e-157 525.2 0.0 1.3e-157 524.9 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KZN90898.1 - 1.2e-16 61.0 0.0 3.1e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KZN90898.1 - 9.6e-14 51.4 0.1 1.6e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Aldedh PF00171.22 KZN90899.1 - 2.5e-182 606.5 0.4 2.9e-182 606.3 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KZN90899.1 - 0.082 12.3 0.0 0.7 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) AA_permease_2 PF13520.6 KZN90900.1 - 6.7e-57 193.2 49.2 7.8e-57 193.0 49.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN90900.1 - 4.8e-22 78.2 37.5 6.4e-22 77.8 37.5 1.1 1 0 0 1 1 1 1 Amino acid permease Kelch_5 PF13854.6 KZN90901.1 - 1.3e-14 53.8 8.2 8.8e-14 51.1 0.6 3.7 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.25 KZN90901.1 - 6.9e-07 28.7 2.6 0.0089 15.6 0.2 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 KZN90901.1 - 0.00055 19.9 6.5 0.33 11.0 0.1 4.7 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_6 PF13964.6 KZN90901.1 - 0.0055 16.9 5.1 0.034 14.4 0.3 3.4 4 0 0 4 4 4 1 Kelch motif PTP_tm PF18861.1 KZN90901.1 - 0.032 14.2 1.0 0.057 13.4 1.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J VLPT PF07122.11 KZN90901.1 - 0.056 13.2 0.1 0.15 11.8 0.1 1.7 1 0 0 1 1 1 0 Variable length PCR target protein (VLPT) DUF4381 PF14316.6 KZN90901.1 - 0.057 13.7 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CARDB PF07705.11 KZN90901.1 - 0.078 13.2 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 CARDB SKG6 PF08693.10 KZN90901.1 - 0.33 10.4 2.5 0.74 9.3 2.5 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SARAF PF06682.12 KZN90901.1 - 0.81 9.3 6.0 1.6 8.3 6.0 1.5 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Peptidase_M20 PF01546.28 KZN90903.1 - 1e-20 74.3 0.0 1.7e-20 73.6 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KZN90903.1 - 4e-13 49.2 0.1 1.7e-12 47.2 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain GATase PF00117.28 KZN90904.1 - 0.0011 18.7 0.0 0.0018 18.1 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I ThiJ_like PF17124.5 KZN90904.1 - 0.043 13.5 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 ThiJ/PfpI family-like SNO PF01174.19 KZN90904.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family HAD_2 PF13419.6 KZN90905.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.6 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KZN90905.1 - 0.2 11.9 0.0 0.43 10.8 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase AA_permease PF00324.21 KZN90906.1 - 8.8e-112 374.1 40.4 1.1e-111 373.9 40.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KZN90906.1 - 2.2e-29 102.5 40.1 3e-29 102.1 40.1 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_MOT1 PF16983.5 KZN90906.1 - 0.0054 17.1 4.3 0.0054 17.1 4.3 2.8 3 0 0 3 3 3 1 Molybdate transporter of MFS superfamily DUF3392 PF11872.8 KZN90906.1 - 0.71 10.2 12.1 20 5.5 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3392) Zn_clus PF00172.18 KZN90907.1 - 2.2e-09 37.3 8.9 5.2e-09 36.1 8.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN90907.1 - 0.0034 16.5 0.0 0.0063 15.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TRAM_LAG1_CLN8 PF03798.16 KZN90908.1 - 4.3e-34 118.0 18.8 4.3e-34 118.0 18.8 1.7 3 0 0 3 3 3 1 TLC domain TRAM1 PF08390.11 KZN90908.1 - 8.1e-23 79.9 0.0 2.5e-22 78.3 0.0 1.8 1 0 0 1 1 1 1 TRAM1-like protein BRO1 PF03097.18 KZN90909.1 - 4.9e-122 407.5 0.0 1.3e-121 406.1 0.0 1.7 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KZN90909.1 - 2.6e-83 279.7 5.5 4.4e-83 279.0 5.5 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV SET PF00856.28 KZN90910.1 - 2e-14 54.3 0.3 7e-14 52.6 0.3 1.8 1 1 0 1 1 1 1 SET domain SAF PF08666.12 KZN90910.1 - 0.21 12.2 0.0 36 5.1 0.0 2.3 2 0 0 2 2 2 0 SAF domain Mito_carr PF00153.27 KZN90911.1 - 1.2e-41 140.6 4.1 1.5e-15 56.9 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Thiolase_N PF00108.23 KZN90912.1 - 3.3e-16 59.4 0.0 7.4e-16 58.3 0.0 1.6 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KZN90912.1 - 3.1e-12 46.2 0.6 5.8e-11 42.1 0.0 2.4 1 1 1 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KZN90912.1 - 7.6e-07 28.9 0.5 4.8e-05 23.1 0.1 2.8 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 KZN90912.1 - 0.0055 15.4 0.2 0.024 13.4 0.1 1.9 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) ketoacyl-synt PF00109.26 KZN90912.1 - 0.0061 16.2 0.6 0.016 14.8 0.6 1.7 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Peptidase_S49 PF01343.18 KZN90912.1 - 0.028 14.4 0.0 0.43 10.5 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 DUF3431 PF11913.8 KZN90913.1 - 8.3e-68 228.4 0.0 1e-67 228.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Med8 PF10232.9 KZN90914.1 - 0.0066 16.1 1.5 0.0075 15.9 1.5 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 DUF4366 PF14283.6 KZN90914.1 - 0.019 15.0 0.3 0.028 14.5 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) PT PF04886.12 KZN90914.1 - 0.028 14.0 3.8 0.028 14.0 3.8 2.3 2 0 0 2 2 2 0 PT repeat PEARLI-4 PF05278.12 KZN90914.1 - 0.09 12.4 1.9 0.12 11.9 1.9 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Roughex PF06020.11 KZN90914.1 - 0.26 10.3 2.2 0.29 10.2 2.2 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Presenilin PF01080.17 KZN90914.1 - 0.77 8.5 1.9 1 8.0 1.9 1.2 1 0 0 1 1 1 0 Presenilin SMN PF06003.12 KZN90915.1 - 8.9e-07 28.4 6.6 0.00013 21.3 1.1 2.1 1 1 0 2 2 2 2 Survival motor neuron protein (SMN) RRM_1 PF00076.22 KZN90916.1 - 3.7e-13 49.1 0.0 8.7e-13 47.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 KZN90916.1 - 0.05 13.6 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 RL domain Nup35_RRM_2 PF14605.6 KZN90916.1 - 0.079 13.0 0.5 0.19 11.8 0.2 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif CHD5 PF04420.14 KZN90917.1 - 2.9e-62 209.2 4.6 3.8e-62 208.8 4.6 1.1 1 0 0 1 1 1 1 CHD5-like protein PPTA PF01239.22 KZN90918.1 - 0.00011 21.8 5.7 0.24 11.2 0.0 3.4 3 0 0 3 3 3 2 Protein prenyltransferase alpha subunit repeat 4F5 PF04419.14 KZN90919.1 - 4.3e-10 40.3 4.3 4.3e-10 40.3 4.3 2.2 2 0 0 2 2 2 1 4F5 protein family DUF4464 PF14713.6 KZN90919.1 - 0.11 12.1 2.1 0.11 12.1 2.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4464) Neurensin PF14927.6 KZN90920.1 - 0.46 10.2 3.1 0.42 10.3 0.6 2.0 1 1 1 2 2 2 0 Neurensin DUF3093 PF11292.8 KZN90920.1 - 1 9.6 6.9 0.18 12.1 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) Gram_pos_anchor PF00746.21 KZN90920.1 - 7.1 6.7 5.8 2 8.4 0.4 2.5 2 0 0 2 2 2 0 LPXTG cell wall anchor motif TRAM_LAG1_CLN8 PF03798.16 KZN90921.1 - 9e-42 143.1 20.9 9e-42 143.1 20.9 2.0 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KZN90921.1 - 2.5e-18 65.5 0.0 5.4e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 TRAM1-like protein MFS_1 PF07690.16 KZN90923.1 - 1.2e-15 57.3 42.9 1.3e-15 57.2 39.0 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KZN90923.1 - 4.5e-07 28.7 8.9 4.5e-07 28.7 8.9 1.5 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Spc7 PF08317.11 KZN90924.1 - 0.028 13.3 2.2 0.031 13.1 2.2 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 KZN90924.1 - 0.059 13.4 0.1 0.086 12.9 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) YabA PF06156.13 KZN90924.1 - 0.1 13.3 2.9 3 8.5 0.2 2.0 1 1 1 2 2 2 0 Initiation control protein YabA Zn_clus PF00172.18 KZN90925.1 - 1.1e-05 25.4 9.8 2.6e-05 24.3 9.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rad10 PF03834.14 KZN90926.1 - 2.2e-47 159.8 0.1 3.4e-47 159.2 0.1 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH PF00633.23 KZN90926.1 - 0.00054 19.7 0.0 0.002 17.9 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KZN90926.1 - 0.00069 20.2 0.0 0.0016 19.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 KZN90926.1 - 0.033 14.3 0.0 0.077 13.1 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF3381 PF11861.8 KZN90926.1 - 0.31 10.8 1.2 0.61 9.9 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) YjbE PF11106.8 KZN90926.1 - 1.2 9.5 3.7 2.5 8.4 3.7 1.5 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE RRM_1 PF00076.22 KZN90927.1 - 3.5e-59 196.5 0.1 3.3e-20 71.7 0.1 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KZN90927.1 - 2.8e-06 27.7 4.3 0.44 10.8 0.1 6.0 4 4 2 6 6 6 2 Cytosolic domain of 10TM putative phosphate transporter RRM_Rrp7 PF17799.1 KZN90927.1 - 0.00032 20.5 0.0 0.55 10.0 0.0 3.3 2 1 1 3 3 3 2 Rrp7 RRM-like N-terminal domain RRM_5 PF13893.6 KZN90927.1 - 0.0022 17.6 0.0 1.6 8.3 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 KZN90927.1 - 0.0041 16.7 0.1 6.9 6.4 0.1 3.5 3 1 0 3 3 3 2 Histone lysine methyltransferase SET associated RRM_occluded PF16842.5 KZN90927.1 - 0.022 14.6 0.2 0.87 9.5 0.0 2.9 3 0 0 3 3 3 0 Occluded RNA-recognition motif NosL PF05573.12 KZN90927.1 - 0.11 12.9 0.1 5.9 7.3 0.1 2.3 2 0 0 2 2 2 0 NosL FMN_dh PF01070.18 KZN90927.1 - 0.12 11.4 0.3 0.21 10.6 0.0 1.6 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KZN90928.1 - 3.5e-09 36.7 0.0 3.8e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AA_permease PF00324.21 KZN90929.1 - 5.4e-96 322.1 32.4 7.2e-96 321.6 32.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KZN90929.1 - 5.3e-16 58.5 29.4 5.4e-16 58.4 28.8 1.2 1 1 0 1 1 1 1 Amino acid permease Cupin_8 PF13621.6 KZN90931.1 - 2.4e-21 76.6 0.0 7.4e-21 75.0 0.0 1.6 1 1 0 1 1 1 1 Cupin-like domain Pyr_redox_3 PF13738.6 KZN90932.1 - 1.4e-11 44.2 0.0 0.00018 20.8 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KZN90932.1 - 8e-08 31.2 0.3 6.6e-07 28.1 0.3 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KZN90932.1 - 7.3e-07 28.6 0.2 3e-05 23.3 0.1 2.9 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KZN90932.1 - 8.4e-06 25.9 0.0 2.7e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KZN90932.1 - 0.011 15.0 0.1 0.26 10.5 0.0 2.7 3 0 0 3 3 3 0 Thi4 family LIN52 PF10044.9 KZN90932.1 - 0.018 15.8 0.0 0.073 13.8 0.0 2.0 2 0 0 2 2 2 0 Retinal tissue protein Fungal_trans PF04082.18 KZN90933.1 - 7.4e-19 67.8 0.1 1.4e-18 66.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN90933.1 - 9.9e-08 32.0 13.4 1.7e-07 31.3 13.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HalX PF08663.10 KZN90933.1 - 0.16 12.3 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 HalX domain CK_II_beta PF01214.18 KZN90934.1 - 5.8e-78 260.9 0.0 1.4e-77 259.6 0.0 1.6 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.8 KZN90934.1 - 0.18 12.8 12.3 0.083 13.9 6.5 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal RRN3 PF05327.11 KZN90934.1 - 0.2 10.2 0.9 0.33 9.4 0.9 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 KZN90934.1 - 3.2 5.7 4.7 4.9 5.1 4.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi bZIP_1 PF00170.21 KZN90935.1 - 0.0011 19.0 8.7 0.0021 18.1 8.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KZN90935.1 - 0.013 15.5 8.2 0.022 14.8 8.2 1.3 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_Maf PF03131.17 KZN90935.1 - 0.029 14.9 2.4 0.069 13.7 2.4 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor Aminotran_4 PF01063.19 KZN90936.1 - 3.6e-36 125.1 0.0 4.8e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Pkinase PF00069.25 KZN90937.1 - 8.3e-17 61.4 0.0 2.2e-16 60.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN90937.1 - 1.8e-08 34.0 0.0 1.6e-07 30.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3433 PF11915.8 KZN90937.1 - 0.093 13.2 0.0 0.42 11.1 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3433) Peptidase_M49 PF03571.15 KZN90938.1 - 5.8e-242 803.9 0.0 7.5e-242 803.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 PRA-PH PF01503.17 KZN90938.1 - 0.11 12.9 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase SNF5 PF04855.12 KZN90940.1 - 9.1e-88 294.0 0.0 1.2e-87 293.7 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 KZN90940.1 - 7e-06 25.6 1.3 1.9e-05 24.2 1.3 1.8 1 0 0 1 1 1 1 GATA zinc finger Rubredoxin_2 PF18073.1 KZN90940.1 - 0.1 12.3 4.6 0.13 12.0 1.2 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain DUF4336 PF14234.6 KZN90941.1 - 1e-16 61.0 0.0 1.3e-12 47.6 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) MARVEL PF01284.23 KZN90942.1 - 3.9e-19 69.1 11.8 4.9e-19 68.8 11.8 1.1 1 0 0 1 1 1 1 Membrane-associating domain MpPF26 PF07666.11 KZN90942.1 - 0.12 12.5 1.3 0.58 10.3 0.0 2.1 1 1 1 2 2 2 0 M penetrans paralogue family 26 DUF2207 PF09972.9 KZN90942.1 - 0.35 9.6 1.7 0.44 9.3 1.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) phiKZ_IP PF12699.7 KZN90943.1 - 0.2 10.8 0.0 0.24 10.5 0.0 1.0 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins Porphobil_deam PF01379.20 KZN90944.1 - 2.1e-73 246.2 0.0 4.3e-73 245.2 0.0 1.5 2 0 0 2 2 2 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KZN90944.1 - 1.1e-21 77.0 0.3 2.2e-21 76.0 0.3 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Hydantoinase_B PF02538.14 KZN90945.1 - 2.9e-200 666.1 4.2 5.2e-200 665.2 4.2 1.4 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KZN90945.1 - 2e-99 332.5 0.0 6.9e-99 330.8 0.0 1.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KZN90945.1 - 9.8e-58 194.8 0.0 3.7e-56 189.6 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region EVE PF01878.18 KZN90945.1 - 0.0075 16.3 0.5 0.015 15.3 0.5 1.4 1 0 0 1 1 1 1 EVE domain MFS_1 PF07690.16 KZN90946.1 - 2.9e-25 89.0 32.3 2.9e-25 89.0 32.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Orf78 PF06024.12 KZN90946.1 - 0.13 12.6 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 Orf78 (ac78) DUF485 PF04341.12 KZN90946.1 - 3.2 7.8 7.1 3.2 7.8 3.2 2.9 2 1 0 2 2 2 0 Protein of unknown function, DUF485 DIOX_N PF14226.6 KZN90947.1 - 9.8e-17 61.8 0.0 5e-14 53.1 0.0 2.4 1 1 1 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KZN90947.1 - 3e-11 43.7 0.0 6.3e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans_2 PF11951.8 KZN90948.1 - 3.5e-50 170.9 5.8 4.9e-50 170.4 5.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain L_protein_N PF15518.6 KZN90948.1 - 0.14 12.0 0.0 9.7 6.1 0.0 2.5 2 0 0 2 2 2 0 L protein N-terminus LCCL PF03815.19 KZN90949.1 - 6.8e-22 77.4 0.0 1.2e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 LCCL domain Metallophos PF00149.28 KZN90950.1 - 3.8e-11 43.9 0.3 1.2e-10 42.3 0.0 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KZN90950.1 - 3.1e-06 27.5 0.4 8.8e-06 26.0 0.2 2.0 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Cupin_3 PF05899.12 KZN90950.1 - 3.3e-06 26.7 0.2 8.2e-06 25.4 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.12 KZN90950.1 - 0.0044 16.8 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ ThiF PF00899.21 KZN90951.1 - 1.4e-41 142.5 0.0 2.1e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 KZN90951.1 - 0.0024 18.2 0.7 0.054 13.8 0.7 2.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KZN90951.1 - 0.0044 17.3 0.1 0.012 15.8 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 KZN90951.1 - 0.028 14.0 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Melibiase_2 PF16499.5 KZN90951.1 - 0.028 13.6 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Alpha galactosidase A ApbA PF02558.16 KZN90951.1 - 0.034 13.8 0.0 0.068 12.8 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 KZN90951.1 - 0.058 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding CD99L2 PF12301.8 KZN90951.1 - 0.094 13.0 0.2 0.2 11.9 0.2 1.5 1 0 0 1 1 1 0 CD99 antigen like protein 2 AA_permease_2 PF13520.6 KZN90952.1 - 3.1e-50 171.3 34.5 4e-50 170.9 34.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN90952.1 - 2.4e-11 42.9 29.9 4.1e-11 42.1 29.9 1.3 1 1 0 1 1 1 1 Amino acid permease Hexapep_2 PF14602.6 KZN90953.1 - 2.4e-11 43.2 4.1 1.3e-08 34.4 1.7 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 KZN90953.1 - 1.1e-10 41.6 0.2 1.7e-10 41.0 0.2 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 KZN90953.1 - 1e-09 37.7 5.7 6.9e-08 31.9 3.3 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Abhydrolase_1 PF00561.20 KZN90954.1 - 9.8e-48 163.0 0.0 4e-47 161.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KZN90954.1 - 0.00074 19.2 0.1 0.0023 17.6 0.0 1.8 2 0 0 2 2 2 1 Putative esterase Gly_transf_sug PF04488.15 KZN90956.1 - 1.8e-13 50.9 0.0 2.9e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif FAD_binding_4 PF01565.23 KZN90958.1 - 9e-24 83.8 1.1 1.9e-23 82.8 1.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KZN90958.1 - 4.2e-12 46.0 1.5 8.6e-12 45.0 1.5 1.6 1 0 0 1 1 1 1 Berberine and berberine like DapB_N PF01113.20 KZN90958.1 - 0.011 15.9 0.0 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Pkinase PF00069.25 KZN90959.1 - 6.8e-64 215.8 0.0 8.5e-64 215.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN90959.1 - 1.6e-36 126.0 0.0 2.1e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KZN90959.1 - 0.0013 17.8 0.0 0.0017 17.4 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KZN90959.1 - 0.016 15.1 0.1 0.12 12.3 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KZN90959.1 - 0.02 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 KZN90959.1 - 0.058 13.0 0.1 0.39 10.3 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 KZN90959.1 - 0.063 12.3 0.0 0.094 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 KZN90959.1 - 0.13 11.0 0.0 0.3 9.8 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase ATP-synt_C PF00137.21 KZN90960.1 - 1.3e-21 76.7 25.3 1.7e-17 63.5 13.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CNH PF00780.22 KZN90961.1 - 3.4e-81 272.9 0.0 7.5e-81 271.7 0.0 1.6 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 KZN90961.1 - 7.7e-44 149.1 0.0 1.8e-43 147.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KZN90961.1 - 1.3e-36 126.6 0.0 2.5e-36 125.6 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 KZN90961.1 - 4.6e-13 49.0 0.0 1.3e-12 47.6 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Septin PF00735.18 KZN90962.1 - 7.3e-103 343.7 0.3 1.4e-102 342.8 0.0 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KZN90962.1 - 3.9e-05 23.7 0.0 9.7e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KZN90962.1 - 0.0016 18.0 0.4 0.11 12.0 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KZN90962.1 - 0.0024 17.8 2.7 0.0063 16.4 0.1 2.7 3 1 0 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 KZN90962.1 - 0.019 15.0 6.3 1.6 8.8 0.0 3.1 2 1 1 3 3 3 0 Dynamin family IIGP PF05049.13 KZN90962.1 - 0.061 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 KZN90962.1 - 0.088 13.1 0.0 0.35 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain EB1 PF03271.17 KZN90962.1 - 0.28 11.4 4.4 2.9 8.2 0.9 2.7 2 0 0 2 2 2 0 EB1-like C-terminal motif Ribosomal_S17e PF00833.18 KZN90962.1 - 4 7.4 6.6 9.4 6.2 6.6 1.6 1 0 0 1 1 1 0 Ribosomal S17 WD40 PF00400.32 KZN90963.1 - 6.5e-07 30.0 0.1 0.094 13.6 0.0 3.6 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN90963.1 - 0.00025 21.3 0.0 0.011 16.0 0.0 3.0 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 KZN90963.1 - 0.004 16.5 0.0 0.2 10.9 0.0 2.5 1 1 1 2 2 2 1 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 KZN90963.1 - 0.0057 15.7 0.0 0.16 10.9 0.0 2.1 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 KZN90963.1 - 0.065 11.2 0.0 0.12 10.4 0.0 1.3 1 1 0 1 1 1 0 IKI3 family Frtz PF11768.8 KZN90963.1 - 0.28 9.4 0.0 0.43 8.8 0.0 1.1 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz RRM_1 PF00076.22 KZN90964.1 - 8.6e-20 70.3 0.0 2.2e-19 69.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KZN90964.1 - 7.5e-06 26.0 0.0 2.1e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif OB_RNB PF08206.11 KZN90964.1 - 0.15 11.8 1.9 0.73 9.6 0.0 2.8 2 0 0 2 2 2 0 Ribonuclease B OB domain DLIC PF05783.11 KZN90965.1 - 1.2e-36 126.6 0.2 5.1e-35 121.2 0.0 2.6 1 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) Spermine_synth PF01564.17 KZN90966.1 - 7.4e-09 35.3 0.0 1.4e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_30 PF05430.11 KZN90966.1 - 0.06 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase EmrE PF13536.6 KZN90966.1 - 0.21 11.1 5.0 0.17 11.4 2.8 1.8 2 0 0 2 2 2 0 Putative multidrug resistance efflux transporter Jiraiya PF15038.6 KZN90966.1 - 4.2 6.8 6.6 9 5.7 4.0 2.1 2 0 0 2 2 2 0 Jiraiya DUF2052 PF09747.9 KZN90967.1 - 1.9e-21 77.1 14.8 2.9e-11 43.9 0.3 2.1 1 1 1 2 2 2 2 Coiled-coil domain containing protein (DUF2052) AMP-binding PF00501.28 KZN90968.1 - 7.9e-97 324.5 0.0 9.7e-97 324.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KZN90968.1 - 2.5e-18 66.8 0.0 5.6e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SET PF00856.28 KZN90969.1 - 2.2e-07 31.4 0.1 2.2e-07 31.4 0.1 3.8 2 2 0 2 2 2 1 SET domain HC2 PF07382.11 KZN90969.1 - 8.9e-06 25.9 45.0 1.3e-05 25.3 45.0 1.2 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Ndc1_Nup PF09531.10 KZN90969.1 - 0.051 12.3 8.0 0.061 12.0 8.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pkinase_fungal PF17667.1 KZN90969.1 - 0.77 8.5 10.9 1.1 7.9 10.9 1.3 1 0 0 1 1 1 0 Fungal protein kinase DUF4407 PF14362.6 KZN90969.1 - 2.6 7.3 18.1 3.7 6.8 18.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Acetyltransf_11 PF13720.6 KZN90969.1 - 3.4 8.2 5.2 15 6.1 0.9 2.4 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Borrelia_P83 PF05262.11 KZN90969.1 - 5.9 5.3 23.5 7.8 4.9 23.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Mitofilin PF09731.9 KZN90969.1 - 9.9 4.9 27.1 12 4.6 27.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein UBA_4 PF14555.6 KZN90970.1 - 1.6e-12 47.0 0.4 3e-11 42.9 0.3 2.6 2 0 0 2 2 2 1 UBA-like domain UIM PF02809.20 KZN90970.1 - 1 9.4 4.9 0.63 10.1 0.8 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif Dynactin_p22 PF07426.11 KZN90971.1 - 7.9e-10 38.8 0.0 1.1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Dynactin subunit p22 SH3_1 PF00018.28 KZN90972.1 - 1e-08 34.6 0.1 1.9e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KZN90972.1 - 2.4e-06 27.1 0.0 5.2e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KZN90972.1 - 1.1e-05 25.2 0.0 2.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF4203 PF13886.6 KZN90972.1 - 0.041 13.5 11.9 0.059 13.0 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) TMEM220 PF15071.6 KZN90972.1 - 0.23 12.2 2.4 0.45 11.3 2.2 1.6 1 1 0 1 1 1 0 Transmembrane family 220, helix APH PF01636.23 KZN90973.1 - 3.8e-21 76.1 0.0 5e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KZN90973.1 - 0.012 15.3 0.0 0.044 13.4 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Choline_kinase PF01633.20 KZN90973.1 - 0.016 14.8 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 KZN90973.1 - 0.017 14.5 0.0 0.049 13.0 0.0 1.7 2 0 0 2 2 2 0 Protein kinase domain SNCAIP_SNCA_bd PF16700.5 KZN90973.1 - 0.088 12.5 0.2 0.18 11.5 0.2 1.5 1 0 0 1 1 1 0 Synphilin-1 alpha-Synuclein-binding domain Response_reg PF00072.24 KZN90974.1 - 5.2e-20 71.7 0.0 1.6e-13 50.8 0.0 2.2 2 0 0 2 2 2 2 Response regulator receiver domain SH3_3 PF08239.11 KZN90975.1 - 0.00054 20.2 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain NLPC_P60 PF00877.19 KZN90975.1 - 0.031 14.3 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 NlpC/P60 family SH3_4 PF06347.13 KZN90975.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain Bot1p PF12298.8 KZN90976.1 - 1.8e-51 174.7 0.3 1.8e-51 174.7 0.3 1.7 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein RF-1 PF00472.20 KZN90976.1 - 0.057 13.3 1.2 0.13 12.2 1.2 1.6 1 0 0 1 1 1 0 RF-1 domain PUL PF08324.11 KZN90977.1 - 6.2e-77 258.5 1.0 9.9e-77 257.9 1.0 1.3 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 KZN90977.1 - 2.1e-45 153.6 0.1 4e-45 152.7 0.1 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 KZN90977.1 - 1.4e-32 111.2 10.2 7.5e-08 32.9 1.3 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.6 KZN90977.1 - 0.003 17.6 0.0 0.19 11.8 0.0 2.8 1 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 KZN90977.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 WD40-like domain YjeF_N PF03853.15 KZN90978.1 - 3.9e-34 118.0 0.0 4.8e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Ribosomal_S16 PF00886.19 KZN90979.1 - 1.2e-24 86.1 0.1 1.6e-24 85.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 RRM_1 PF00076.22 KZN90980.1 - 7.3e-17 60.9 0.0 2.7e-14 52.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KZN90980.1 - 0.052 13.4 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif WD40 PF00400.32 KZN90981.1 - 3.7e-21 75.0 12.2 3.1e-07 31.0 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN90981.1 - 9.9e-08 32.2 0.2 0.18 12.1 0.0 4.5 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KZN90981.1 - 0.0011 18.0 0.1 0.2 10.5 0.0 2.6 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Me-amine-dh_H PF06433.11 KZN90981.1 - 0.0016 17.3 0.0 0.14 11.0 0.0 2.1 2 0 0 2 2 2 2 Methylamine dehydrogenase heavy chain (MADH) Cytochrom_D1 PF02239.16 KZN90981.1 - 0.038 12.5 0.0 0.066 11.7 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain dsrm PF00035.26 KZN90981.1 - 0.11 13.3 0.0 0.3 11.8 0.0 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding motif RRM_1 PF00076.22 KZN90982.1 - 3e-16 59.0 0.0 5e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KZN90982.1 - 5.7e-06 26.8 11.3 5.7e-06 26.8 11.3 4.4 3 1 1 4 4 4 3 C-terminal duplication domain of Friend of PRMT1 CH PF00307.31 KZN90983.1 - 6.5e-46 155.0 0.0 9.3e-22 77.3 0.0 3.1 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KZN90983.1 - 1e-26 92.8 0.2 2.8e-26 91.4 0.2 1.8 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 KZN90983.1 - 3.1e-09 36.6 0.6 2.5e-05 24.0 0.1 2.8 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.6 KZN90983.1 - 0.00027 20.6 0.1 0.0017 18.2 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KZN90983.1 - 0.0019 17.6 0.1 0.024 14.2 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KZN90983.1 - 0.014 15.3 0.1 0.11 12.4 0.0 2.6 3 0 0 3 3 3 0 EF-hand domain pair Ribonuc_2-5A PF06479.12 KZN90983.1 - 0.048 13.8 0.2 0.18 12.0 0.2 2.1 1 0 0 1 1 1 0 Ribonuclease 2-5A EF-hand_7 PF13499.6 KZN90983.1 - 0.34 11.4 5.1 0.47 11.0 0.2 3.4 3 0 0 3 3 3 0 EF-hand domain pair Spectrin PF00435.21 KZN90983.1 - 3.9 8.0 7.5 2.4 8.7 0.0 3.5 2 1 2 4 4 4 0 Spectrin repeat PhyH PF05721.13 KZN90984.1 - 7.2e-13 49.3 0.0 1.2e-12 48.6 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans PF04082.18 KZN90985.1 - 2.8e-08 33.1 0.1 6e-08 32.0 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN90985.1 - 8.3e-06 25.8 6.6 1.5e-05 25.0 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KZN90986.1 - 2e-19 70.0 0.0 3.6e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN90986.1 - 2.1e-10 40.3 0.0 1.2e-08 34.5 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase PAR1 PF06521.11 KZN90986.1 - 0.048 13.3 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 PAR1 protein CorA PF01544.18 KZN90987.1 - 4.7e-09 36.0 0.9 6.3e-09 35.6 0.9 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein AA_permease PF00324.21 KZN90988.1 - 1e-23 83.7 29.5 6.7e-13 48.1 7.3 3.5 1 1 1 2 2 2 2 Amino acid permease APH PF01636.23 KZN90989.1 - 1.2e-16 61.4 0.0 1.4e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN90989.1 - 1.5e-06 28.0 0.0 2.1e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 KZN90989.1 - 0.065 12.3 0.0 0.098 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 EcKinase PF02958.20 KZN90989.1 - 0.1 11.9 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Aldo_ket_red PF00248.21 KZN90991.1 - 7.9e-44 150.0 0.0 1.2e-41 142.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family P3A PF08727.11 KZN90991.1 - 0.041 13.3 0.1 0.76 9.2 0.2 2.7 3 0 0 3 3 3 0 Poliovirus 3A protein like ALMT PF11744.8 KZN90991.1 - 0.18 10.6 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Rit1_C PF17184.4 KZN90992.1 - 8.6e-74 248.4 0.0 4.3e-46 157.5 0.0 2.1 1 1 1 2 2 2 2 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 KZN90992.1 - 9.7e-36 122.4 0.0 4.3e-35 120.4 0.0 2.0 2 0 0 2 2 2 1 Rit1 DUSP-like domain HAD_2 PF13419.6 KZN90993.1 - 1.6e-20 73.9 0.1 2.3e-20 73.4 0.1 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KZN90993.1 - 8.2e-07 29.5 0.3 2.5e-06 27.9 0.3 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KZN90993.1 - 2.3e-05 24.4 0.1 4e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KZN90993.1 - 0.0012 19.2 0.0 0.0017 18.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.18 KZN90993.1 - 0.0032 17.2 0.0 0.058 13.2 0.0 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase DUF1456 PF07308.13 KZN90993.1 - 0.17 12.2 0.2 0.54 10.6 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) NUDIX PF00293.28 KZN90994.1 - 9.4e-19 67.8 0.0 1.4e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 KZN90995.1 - 9e-08 32.2 0.0 1.7e-07 31.4 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain EST1_DNA_bind PF10373.9 KZN90996.1 - 0.022 14.2 0.2 0.068 12.6 0.2 1.8 1 1 0 1 1 1 0 Est1 DNA/RNA binding domain ALMS_motif PF15309.6 KZN90996.1 - 1.4 9.4 4.4 0.82 10.1 1.7 1.9 2 0 0 2 2 2 0 ALMS motif DUF2457 PF10446.9 KZN90996.1 - 2.6 7.1 7.7 4 6.5 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Glycos_transf_2 PF00535.26 KZN90997.1 - 1.5e-23 83.4 0.0 1.2e-21 77.3 0.0 2.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KZN90997.1 - 2.1e-07 31.1 0.1 0.0061 16.5 0.1 2.8 2 1 1 3 3 3 2 Glycosyltransferase like family 2 Striatin PF08232.12 KZN90999.1 - 0.0021 18.7 1.3 0.0023 18.5 0.1 1.8 2 0 0 2 2 2 1 Striatin family Autophagy_N PF03986.13 KZN91001.1 - 6.2e-47 159.0 0.0 1.2e-46 158.1 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 KZN91001.1 - 1.3e-15 56.5 0.5 2.4e-15 55.7 0.5 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 KZN91001.1 - 2.6e-13 50.3 0.1 4.7e-13 49.5 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain AAA_11 PF13086.6 KZN91002.1 - 3.3e-21 76.2 0.1 6.5e-21 75.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain zf-CCCH PF00642.24 KZN91002.1 - 3.9e-07 29.8 1.6 6.8e-07 29.0 1.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KZN91002.1 - 4.3e-07 29.6 2.1 7.3e-07 28.8 2.1 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger AAA_19 PF13245.6 KZN91002.1 - 1.4e-06 28.8 0.0 7.4e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 KZN91002.1 - 1.4e-06 28.1 0.0 3.5e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain zf_CCCH_4 PF18345.1 KZN91002.1 - 3.4e-06 26.9 6.3 6.8e-06 26.0 6.3 1.5 1 0 0 1 1 1 1 Zinc finger domain AAA_30 PF13604.6 KZN91002.1 - 0.00044 20.0 0.6 0.0088 15.8 0.1 2.3 2 0 0 2 2 2 1 AAA domain Torus PF16131.5 KZN91002.1 - 0.002 18.8 1.9 0.0022 18.7 0.2 1.9 2 0 0 2 2 2 1 Torus domain DUF2075 PF09848.9 KZN91002.1 - 0.0024 17.2 0.0 0.0049 16.2 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ORC5_C PF14630.6 KZN91002.1 - 0.079 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus zf-CCCH_2 PF14608.6 KZN91002.1 - 0.93 10.1 2.4 2 9.0 2.4 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger TFIIB PF00382.19 KZN91004.1 - 0.0014 18.7 0.0 0.05 13.6 0.0 2.4 2 1 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_N PF00134.23 KZN91004.1 - 0.0022 17.8 0.0 0.25 11.1 0.0 2.5 2 1 0 2 2 2 2 Cyclin, N-terminal domain LPD39 PF18858.1 KZN91005.1 - 0.018 15.1 5.7 0.018 15.1 5.7 1.4 1 1 0 1 1 1 0 Large polyvalent protein associated domain 39 Exonuc_VII_L PF02601.15 KZN91005.1 - 0.052 13.1 4.2 0.076 12.6 4.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit HAUS5 PF14817.6 KZN91005.1 - 0.081 11.7 10.8 0.11 11.2 10.8 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 DUF2570 PF10828.8 KZN91005.1 - 0.48 10.3 4.8 0.18 11.6 2.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) Phage_GPO PF05929.11 KZN91005.1 - 0.75 9.4 6.5 1.1 8.8 6.5 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4407 PF14362.6 KZN91005.1 - 2 7.7 7.4 3.1 7.1 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Nup88 PF10168.9 KZN91005.1 - 3 5.5 7.8 4.6 4.9 7.8 1.2 1 0 0 1 1 1 0 Nuclear pore component SecY PF00344.20 KZN91006.1 - 2.1e-72 244.0 7.9 2.6e-72 243.7 7.9 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KZN91006.1 - 7.4e-17 60.9 0.3 2e-16 59.5 0.3 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p MARVEL PF01284.23 KZN91006.1 - 0.64 10.0 0.0 0.64 10.0 0.0 3.1 2 1 0 2 2 2 0 Membrane-associating domain ArgJ PF01960.18 KZN91007.1 - 5.4e-151 502.6 0.4 6.3e-151 502.4 0.4 1.0 1 0 0 1 1 1 1 ArgJ family ORC2 PF04084.14 KZN91008.1 - 5.3e-119 397.0 0.0 6.4e-119 396.8 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 ORC6 PF05460.13 KZN91008.1 - 0.53 9.5 10.0 0.88 8.8 10.0 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) FUN14 PF04930.15 KZN91009.1 - 5.9e-10 39.4 0.4 5.9e-10 39.4 0.4 1.7 2 0 0 2 2 2 1 FUN14 family DUF543 PF04418.12 KZN91009.1 - 0.2 11.6 6.9 1.9 8.5 2.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF543) SOR_SNZ PF01680.17 KZN91010.1 - 2.7e-108 360.5 6.7 4e-108 359.9 6.7 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 KZN91010.1 - 4.7e-09 35.9 6.8 2.4e-06 27.0 0.2 2.5 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 KZN91010.1 - 0.00026 20.2 0.9 0.13 11.4 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) TetR_C_27 PF17935.1 KZN91010.1 - 0.00082 19.4 0.0 0.0048 16.9 0.0 2.1 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain His_biosynth PF00977.21 KZN91010.1 - 0.0025 17.3 0.5 0.13 11.6 0.1 3.0 2 2 1 3 3 3 1 Histidine biosynthesis protein IGPS PF00218.21 KZN91010.1 - 0.0032 16.7 0.1 0.31 10.2 0.0 2.5 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.14 KZN91010.1 - 0.0078 15.4 1.0 0.17 11.1 0.0 2.5 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.15 KZN91010.1 - 0.04 13.3 7.2 0.055 12.8 0.3 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase OMPdecase PF00215.24 KZN91010.1 - 0.049 13.2 0.2 3.9 7.0 0.0 2.3 1 1 1 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family IBN_N PF03810.19 KZN91011.1 - 5.7e-06 26.2 0.8 1.4e-05 24.9 0.8 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain Importin_rep PF18773.1 KZN91011.1 - 0.00031 20.4 0.0 0.0006 19.5 0.0 1.5 1 0 0 1 1 1 1 Importin 13 repeat Importin_rep_3 PF18806.1 KZN91011.1 - 0.0011 19.0 0.0 0.017 15.1 0.0 2.9 2 0 0 2 2 2 1 Importin 13 repeat Phage_Coat_Gp8 PF05371.12 KZN91011.1 - 0.081 12.7 0.7 1.8 8.4 0.0 2.8 2 0 0 2 2 2 0 Phage major coat protein, Gp8 DUF577 PF04510.12 KZN91011.1 - 0.24 11.3 0.9 0.72 9.7 0.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF577) Creatinase_N_2 PF16189.5 KZN91012.1 - 1.4e-54 184.6 0.1 5.8e-53 179.3 0.0 2.3 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KZN91012.1 - 5.1e-40 137.4 0.0 7.5e-40 136.9 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KZN91012.1 - 1e-21 76.8 0.4 2.7e-21 75.4 0.4 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KZN91012.1 - 4.6e-18 66.2 0.0 1.1e-16 61.7 0.0 2.8 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Sec8_exocyst PF04048.14 KZN91013.1 - 1.5e-44 151.4 1.2 4.2e-44 149.9 1.2 1.8 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KZN91013.1 - 7e-09 35.4 0.2 1.4e-08 34.4 0.2 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 KZN91013.1 - 0.001 17.7 0.4 0.0019 16.8 0.4 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Dor1 PF04124.12 KZN91013.1 - 0.029 13.1 1.9 0.051 12.3 1.9 1.3 1 0 0 1 1 1 0 Dor1-like family DPBB_1 PF03330.18 KZN91014.1 - 1e-07 32.1 0.0 3.6e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 KZN91014.1 - 0.0015 18.5 0.6 0.0031 17.5 0.6 1.6 1 0 0 1 1 1 1 Pollen allergen InPase PF18823.1 KZN91014.1 - 0.13 12.0 0.1 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 Inorganic Pyrophosphatase Inhibitor_I9 PF05922.16 KZN91015.1 - 2.6e-09 37.6 0.0 3e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 Sigma_reg_C PF13791.6 KZN91015.1 - 0.061 13.5 0.0 0.065 13.5 0.0 1.0 1 0 0 1 1 1 0 Sigma factor regulator C-terminal DAHP_snth_FXD PF18152.1 KZN91015.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.7 1 1 0 1 1 1 0 DAHP synthase ferredoxin-like domain HLH PF00010.26 KZN91016.1 - 3.4e-13 49.3 2.8 7.2e-13 48.3 2.8 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2400 PF09674.10 KZN91016.1 - 0.12 12.4 0.1 0.17 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) CN_hydrolase PF00795.22 KZN91017.1 - 1.3e-13 50.9 0.0 3.4e-13 49.5 0.0 1.7 1 1 1 2 2 2 1 Carbon-nitrogen hydrolase Pkinase PF00069.25 KZN91018.1 - 5.3e-19 68.6 0.0 2.1e-09 37.1 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KZN91018.1 - 1.1e-08 34.7 0.5 0.00039 19.8 0.0 3.5 4 0 0 4 4 4 2 Protein tyrosine kinase SAC3_GANP PF03399.16 KZN91019.1 - 8.8e-104 347.0 4.2 1.2e-103 346.6 4.2 1.2 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KZN91019.1 - 6.4e-06 26.2 0.0 1.7e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family DUF2841 PF11001.8 KZN91020.1 - 7.5e-45 152.0 0.0 1.4e-44 151.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) ABC_membrane PF00664.23 KZN91021.1 - 8e-84 281.5 27.6 4.6e-47 161.0 9.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KZN91021.1 - 1.8e-51 174.3 0.0 7.7e-30 104.2 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KZN91021.1 - 1.4e-09 37.7 3.5 0.0073 15.8 0.1 4.1 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KZN91021.1 - 3.1e-06 27.2 0.6 0.092 12.8 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KZN91021.1 - 6.5e-05 22.9 0.2 0.019 14.9 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KZN91021.1 - 0.0002 21.8 0.3 0.46 10.8 0.3 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KZN91021.1 - 0.00069 19.3 0.4 1.8 8.4 0.0 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 KZN91021.1 - 0.0018 18.4 0.5 1.8 8.6 0.1 2.8 2 0 0 2 2 2 2 Helicase HerA, central domain Dynamin_N PF00350.23 KZN91021.1 - 0.0022 18.0 0.2 0.33 11.0 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_21 PF13304.6 KZN91021.1 - 0.0064 16.3 0.2 1.8 8.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KZN91021.1 - 0.0076 16.8 0.1 0.92 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KZN91021.1 - 0.012 15.3 1.4 0.35 10.6 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KZN91021.1 - 0.02 15.1 1.5 4.1 7.7 0.0 3.4 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KZN91021.1 - 0.034 13.9 0.3 2.5 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 KZN91021.1 - 0.039 14.2 2.0 11 6.2 0.0 3.6 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 KZN91021.1 - 0.14 12.6 0.0 7.5 7.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 KZN91021.1 - 0.69 9.8 5.4 0.4 10.6 0.1 2.8 3 0 0 3 3 3 0 NACHT domain Ank_3 PF13606.6 KZN91022.1 - 2.6e-12 45.7 1.1 0.037 14.6 0.0 7.1 7 0 0 7 7 7 2 Ankyrin repeat Ank_2 PF12796.7 KZN91022.1 - 2.5e-10 40.8 0.0 0.0023 18.5 0.0 3.8 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN91022.1 - 2.6e-09 37.4 0.4 0.022 15.4 0.0 5.7 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 KZN91022.1 - 1.2e-07 31.8 1.0 0.16 12.5 0.0 5.4 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 KZN91022.1 - 4.4e-06 26.9 0.8 3.7 8.0 0.0 5.5 4 2 2 6 6 6 2 Ankyrin repeats (many copies) bVLRF1 PF18826.1 KZN91024.1 - 6.3e-62 207.9 0.5 1.3e-61 206.9 0.5 1.5 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 KZN91024.1 - 7.4e-07 29.3 0.0 1.8e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KZN91024.1 - 0.0028 18.0 1.2 0.0081 16.6 1.2 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 KZN91024.1 - 0.065 13.8 0.0 0.15 12.7 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) zf-C2H2_2 PF12756.7 KZN91024.1 - 0.15 12.5 0.1 0.29 11.5 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) RPA43_OB PF17875.1 KZN91024.1 - 0.31 11.7 5.2 2.2 8.9 2.8 3.1 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I Myb_DNA-bind_6 PF13921.6 KZN91025.1 - 0.00015 22.0 0.1 0.00026 21.2 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KZN91025.1 - 0.00045 20.3 0.6 0.00078 19.6 0.6 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Adap_comp_sub PF00928.21 KZN91026.1 - 4.5e-84 281.9 0.0 5.5e-84 281.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KZN91026.1 - 2.6e-05 24.2 0.0 4.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KZN91026.1 - 0.0028 17.1 0.2 0.0055 16.2 0.2 1.5 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain p450 PF00067.22 KZN91027.1 - 4.6e-68 230.0 0.0 5.3e-68 229.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4203 PF13886.6 KZN91028.1 - 2.3e-52 177.6 25.4 3.2e-52 177.2 25.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Erf4 PF10256.9 KZN91028.1 - 1.2e-38 131.7 0.0 2.4e-38 130.8 0.0 1.5 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family SSB PF00436.25 KZN91029.1 - 8.4e-19 67.5 0.0 1e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Kinocilin PF15033.6 KZN91029.1 - 0.058 13.0 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinocilin protein STE3 PF02076.15 KZN91030.1 - 8.9e-92 307.4 18.9 1.1e-91 307.0 18.9 1.1 1 0 0 1 1 1 1 Pheromone A receptor PHO4 PF01384.20 KZN91030.1 - 0.013 14.6 0.0 0.023 13.7 0.0 1.4 1 1 0 1 1 1 0 Phosphate transporter family DUF3671 PF12420.8 KZN91030.1 - 0.015 15.4 1.4 0.084 13.0 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function Exo_endo_phos PF03372.23 KZN91032.1 - 4.5e-08 32.9 0.0 8.1e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DCP1 PF06058.13 KZN91033.1 - 6.7e-29 100.2 0.0 1.1e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family LIDHydrolase PF10230.9 KZN91034.1 - 2.6e-82 276.4 0.0 3e-82 276.2 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 KZN91034.1 - 1.6e-05 25.7 0.0 2.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KZN91034.1 - 0.0018 17.6 0.0 0.003 16.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KZN91034.1 - 0.015 15.1 0.0 0.037 13.9 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold LCAT PF02450.15 KZN91034.1 - 0.033 13.4 0.0 0.061 12.5 0.0 1.4 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 KZN91034.1 - 0.074 12.8 0.0 0.16 11.7 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein DUF1749 PF08538.10 KZN91034.1 - 0.095 11.8 0.0 0.22 10.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Thioesterase PF00975.20 KZN91034.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain SMK-1 PF04802.15 KZN91035.1 - 1.8e-78 262.7 0.2 3.8e-78 261.7 0.2 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 SLC35F PF06027.12 KZN91036.1 - 1.2e-98 330.4 22.0 1.4e-98 330.1 22.0 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KZN91036.1 - 5.8e-09 35.3 6.2 1.1e-08 34.5 5.8 1.5 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KZN91036.1 - 7.9e-09 35.8 31.4 0.00018 21.7 10.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF2516 PF10724.9 KZN91036.1 - 4.8 7.5 10.1 6.9 7.0 1.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) CALM_bind PF16025.5 KZN91037.1 - 0.11 13.0 6.0 0.22 12.0 6.0 1.5 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding PAP_assoc PF03828.19 KZN91038.1 - 4.5e-18 65.2 0.1 1.2e-17 63.9 0.1 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KZN91038.1 - 0.00012 22.3 0.0 0.00023 21.4 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KZN91038.1 - 0.018 15.1 0.0 0.043 13.9 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase SE PF08491.10 KZN91039.1 - 1.4e-95 319.5 0.0 1.8e-95 319.1 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 KZN91039.1 - 2.3e-11 43.6 0.0 2.7e-10 40.0 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KZN91039.1 - 7.5e-06 25.8 0.2 4.3e-05 23.3 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KZN91039.1 - 0.0023 17.1 0.7 0.0037 16.4 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KZN91039.1 - 0.0025 17.1 0.2 0.0065 15.7 0.0 1.6 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KZN91039.1 - 0.0026 18.0 0.7 0.0055 16.9 0.7 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KZN91039.1 - 0.0033 16.6 0.1 0.075 12.1 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KZN91039.1 - 0.0045 16.3 0.1 0.0078 15.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KZN91039.1 - 0.0046 16.4 0.2 0.0065 15.9 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KZN91039.1 - 0.0055 17.2 0.4 0.027 15.0 0.4 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KZN91039.1 - 0.017 14.2 0.5 0.029 13.4 0.5 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 KZN91039.1 - 0.018 14.7 0.4 0.03 14.0 0.4 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 KZN91039.1 - 0.032 13.6 0.3 0.052 12.9 0.3 1.3 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.20 KZN91039.1 - 0.086 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 KZN91039.1 - 0.1 11.3 0.3 0.16 10.6 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.23 KZN91039.1 - 0.18 11.8 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.14 KZN91039.1 - 0.28 10.0 0.1 0.77 8.5 0.2 1.6 2 0 0 2 2 2 0 Tryptophan halogenase PPR PF01535.20 KZN91040.1 - 0.0018 18.4 1.7 0.37 11.1 0.1 4.1 5 0 0 5 5 5 1 PPR repeat PPR_long PF17177.4 KZN91040.1 - 0.0058 16.0 0.0 0.016 14.6 0.0 1.7 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP USP8_interact PF08941.10 KZN91040.1 - 0.013 15.3 0.0 0.037 13.8 0.0 1.7 1 0 0 1 1 1 0 USP8 interacting PPR_2 PF13041.6 KZN91040.1 - 0.033 14.4 0.6 0.87 9.8 0.0 3.1 4 0 0 4 4 4 0 PPR repeat family TPR_19 PF14559.6 KZN91040.1 - 0.072 13.6 0.0 26 5.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_3 PF13812.6 KZN91040.1 - 0.16 12.0 0.1 1.1 9.4 0.1 2.2 2 0 0 2 2 2 0 Pentatricopeptide repeat domain MFS_1 PF07690.16 KZN91041.1 - 9.8e-24 83.9 40.6 6.2e-23 81.3 24.2 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN91041.1 - 0.00061 18.8 20.5 0.0083 15.0 20.4 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1751 PF08551.10 KZN91041.1 - 0.033 14.7 0.7 0.033 14.7 0.7 2.3 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) LapA_dom PF06305.11 KZN91041.1 - 1.8 8.4 5.6 31 4.5 0.1 3.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Ferrochelatase PF00762.19 KZN91042.1 - 3e-98 328.8 0.0 3.5e-98 328.6 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase MP PF01107.18 KZN91042.1 - 0.2 11.2 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 Viral movement protein (MP) Ku PF02735.16 KZN91043.1 - 2.4e-44 151.5 0.0 5.7e-44 150.3 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KZN91043.1 - 3.4e-33 115.2 0.0 5e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KZN91043.1 - 5.6e-26 91.1 0.0 2.1e-25 89.2 0.0 2.0 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 KZN91043.1 - 2e-11 43.3 0.0 4e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 KZN91043.1 - 0.017 14.8 0.3 0.092 12.5 0.3 2.1 1 1 0 1 1 1 0 HeH/LEM domain VWA_2 PF13519.6 KZN91043.1 - 0.025 15.2 0.0 0.29 11.8 0.0 2.5 1 1 0 1 1 1 0 von Willebrand factor type A domain VWA PF00092.28 KZN91043.1 - 0.11 12.7 0.0 0.97 9.7 0.0 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain DUF3431 PF11913.8 KZN91044.1 - 7.8e-85 284.0 0.3 9.5e-85 283.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) zf-CCCH PF00642.24 KZN91045.1 - 3.7e-09 36.3 1.4 7.1e-09 35.4 1.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KZN91045.1 - 1.8e-07 30.9 5.3 3.3e-07 30.1 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KZN91045.1 - 1.8e-07 31.1 6.5 3.4e-07 30.2 6.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KZN91045.1 - 1.8e-07 30.9 8.5 3.2e-07 30.1 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KZN91045.1 - 1e-06 28.6 8.0 1.7e-06 27.8 8.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KZN91045.1 - 1.6e-06 27.9 9.5 2.8e-06 27.1 9.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 KZN91045.1 - 3.9e-06 26.7 5.4 7e-06 25.9 5.4 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-RING_2 PF13639.6 KZN91045.1 - 4e-06 27.1 6.6 8.3e-06 26.1 6.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_10 PF16685.5 KZN91045.1 - 4.5e-06 26.7 3.1 9.4e-06 25.7 3.1 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-CCCH_4 PF18044.1 KZN91045.1 - 0.00088 19.0 1.2 0.00088 19.0 1.2 1.6 2 0 0 2 2 1 1 CCCH-type zinc finger Prok-RING_4 PF14447.6 KZN91045.1 - 0.0026 17.6 6.0 0.0051 16.7 6.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KZN91045.1 - 0.007 16.5 8.4 0.014 15.6 8.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-CCCH_2 PF14608.6 KZN91045.1 - 0.11 13.0 1.6 0.23 12.0 1.6 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-Nse PF11789.8 KZN91045.1 - 0.12 12.2 2.5 0.24 11.2 2.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 KZN91045.1 - 0.86 9.4 4.3 1.8 8.4 4.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger Mcp5_PH PF12814.7 KZN91046.1 - 7.1e-45 152.1 0.1 1.8e-44 150.8 0.1 1.8 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KZN91046.1 - 4.1e-07 30.5 0.0 1.1e-06 29.1 0.0 1.7 1 0 0 1 1 1 1 PH domain Methyltransf_23 PF13489.6 KZN91047.1 - 1.8e-13 50.6 0.0 2.7e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN91047.1 - 1.9e-09 38.0 0.0 4.8e-09 36.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN91047.1 - 3.3e-05 24.6 0.0 8.8e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN91047.1 - 6.4e-05 23.6 0.0 0.0051 17.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN91047.1 - 0.0013 18.5 0.0 0.0049 16.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KZN91047.1 - 0.062 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family DUF2439 PF10382.9 KZN91048.1 - 1.3e-28 99.1 0.2 2e-28 98.6 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) SH3_9 PF14604.6 KZN91049.1 - 4.5e-16 58.4 0.2 8e-16 57.6 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KZN91049.1 - 3.7e-14 52.0 0.1 6.2e-14 51.3 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KZN91049.1 - 1.2e-09 37.7 0.1 2.1e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.18 KZN91049.1 - 2.5e-08 33.9 3.1 4.2e-08 33.1 3.1 1.3 1 0 0 1 1 1 1 BAR domain Phage_HK97_TLTM PF06120.11 KZN91049.1 - 0.34 10.0 3.0 0.75 8.9 3.1 1.5 1 1 0 1 1 1 0 Tail length tape measure protein RAP-1 PF03085.15 KZN91050.1 - 0.26 10.9 0.1 0.34 10.6 0.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) p450 PF00067.22 KZN91051.1 - 4.6e-50 170.7 0.0 6.6e-50 170.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Nit_Regul_Hom PF10126.9 KZN91051.1 - 0.059 13.4 0.0 0.18 11.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII Abhydrolase_6 PF12697.7 KZN91052.1 - 1.9e-06 28.7 1.2 3.2e-06 27.9 0.3 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KZN91052.1 - 2.7e-05 23.6 0.0 0.00027 20.3 0.0 2.4 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KZN91052.1 - 0.0078 15.9 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.14 KZN91052.1 - 0.098 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Ndr family Alpha-amylase PF00128.24 KZN91053.1 - 7.1e-17 62.0 2.1 3.2e-16 59.8 1.5 2.3 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 KZN91053.1 - 3e-14 53.3 0.1 5.3e-14 52.5 0.1 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KZN91053.1 - 1.3e-05 24.8 0.0 2.7e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KZN91053.1 - 0.13 12.3 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 GST_N_2 PF13409.6 KZN91054.1 - 3.2e-07 30.5 0.0 6.2e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KZN91054.1 - 7.6e-06 26.2 0.0 1.6e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KZN91054.1 - 0.0047 16.9 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KZN91054.1 - 0.022 14.9 0.0 0.037 14.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KZN91054.1 - 0.071 13.3 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Fungal_trans PF04082.18 KZN91055.1 - 4.5e-21 75.1 0.8 8.6e-21 74.1 0.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN91055.1 - 9.3e-06 25.7 8.7 2.2e-05 24.5 8.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KZN91056.1 - 3.2e-73 247.1 15.0 3.7e-73 246.9 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN91056.1 - 1.3e-19 70.3 31.0 1.1e-16 60.7 14.2 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily DAO PF01266.24 KZN91057.1 - 2.4e-33 116.2 0.0 3e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KZN91057.1 - 0.00034 20.8 0.1 0.0011 19.1 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KZN91057.1 - 0.00088 18.6 0.0 0.016 14.4 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KZN91057.1 - 0.011 15.0 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 KZN91057.1 - 0.014 15.5 0.0 4.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 KZN91057.1 - 0.017 14.2 0.0 3.8 6.5 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KZN91057.1 - 0.044 13.1 0.0 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KZN91057.1 - 0.11 13.1 0.0 0.31 11.6 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KZN91057.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Glyco_hydro_3_C PF01915.22 KZN91058.1 - 1.8e-53 181.5 0.1 3.5e-53 180.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KZN91058.1 - 4.9e-33 114.9 0.0 1.7e-32 113.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KZN91058.1 - 1.7e-25 88.9 0.1 3.3e-25 88.0 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DAO PF01266.24 KZN91060.1 - 1.3e-38 133.6 0.2 1.6e-38 133.2 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KZN91060.1 - 0.00045 19.5 0.0 0.015 14.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN91060.1 - 0.0035 17.6 0.1 0.0082 16.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 KZN91060.1 - 0.012 15.8 0.3 0.033 14.5 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.6 KZN91060.1 - 0.04 13.9 2.6 0.17 11.8 0.2 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KZN91060.1 - 0.056 12.5 0.1 0.094 11.7 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 KZN91060.1 - 0.089 11.9 0.3 6.5 5.7 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 KZN91060.1 - 0.11 11.4 0.2 0.54 9.0 0.2 1.8 2 0 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.16 KZN91060.1 - 0.12 12.0 0.5 0.23 11.1 0.5 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF1188 PF06690.11 KZN91060.1 - 0.18 11.3 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Pyr_redox_3 PF13738.6 KZN91060.1 - 0.43 9.8 1.5 1.1 8.5 0.3 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aldedh PF00171.22 KZN91063.1 - 1.5e-137 458.9 0.0 1.8e-137 458.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KZN91063.1 - 0.00061 18.9 0.0 0.00089 18.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) UDPGT PF00201.18 KZN91064.1 - 0.08 11.7 2.0 1.9 7.1 0.5 2.3 1 1 1 2 2 2 0 UDP-glucoronosyl and UDP-glucosyl transferase Fungal_trans PF04082.18 KZN91065.1 - 4.6e-13 48.8 0.2 9.9e-13 47.7 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN91065.1 - 1.7e-08 34.4 4.9 5.6e-08 32.8 4.9 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KZN91065.1 - 1.1e-05 25.5 7.8 0.009 16.4 1.8 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KZN91065.1 - 1.9e-05 25.1 7.1 0.022 15.6 1.5 3.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KZN91065.1 - 0.027 14.8 6.7 0.29 11.5 0.6 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KZN91065.1 - 0.069 13.6 0.4 0.069 13.6 0.4 3.9 4 0 0 4 4 4 0 Zinc-finger double domain zf-met PF12874.7 KZN91065.1 - 0.2 12.1 2.9 2.1 8.8 0.8 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FA_hydroxylase PF04116.13 KZN91066.1 - 8.7e-25 87.6 13.2 8.7e-25 87.6 13.2 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily RTC PF01137.21 KZN91068.1 - 8.5e-49 165.7 0.0 1.1e-48 165.4 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase CPSase_L_D2 PF02786.17 KZN91070.1 - 5.7e-57 192.6 0.0 9e-57 192.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KZN91070.1 - 4.7e-31 107.1 0.0 1e-30 106.0 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KZN91070.1 - 2.9e-29 101.8 0.0 5.4e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KZN91070.1 - 1.3e-10 40.9 0.2 2.8e-10 39.9 0.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KZN91070.1 - 8.2e-08 32.0 0.0 1.8e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KZN91070.1 - 0.00016 21.3 0.0 0.0003 20.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KZN91070.1 - 0.00021 21.4 0.0 0.00043 20.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 KZN91070.1 - 0.0011 18.3 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp RnfC_N PF13375.6 KZN91070.1 - 0.0011 18.8 0.0 0.0026 17.7 0.0 1.5 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.6 KZN91070.1 - 0.036 13.9 0.0 0.084 12.7 0.0 1.6 1 0 0 1 1 1 0 Biotin-lipoyl like ATP-grasp_5 PF13549.6 KZN91070.1 - 0.064 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_Ter PF15632.6 KZN91070.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.11 KZN91070.1 - 0.17 11.4 0.1 1.3 8.5 0.0 2.3 3 0 0 3 3 3 0 RimK-like ATP-grasp domain Carboxyl_trans PF01039.22 KZN91071.1 - 4.9e-78 262.9 0.0 6.2e-78 262.6 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain ArAE_2_N PF10337.9 KZN91072.1 - 6.4e-125 417.9 0.1 9.4e-124 414.0 0.1 2.1 2 0 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 KZN91072.1 - 2.9e-63 213.8 0.0 1.7e-62 211.2 0.0 2.2 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 HPP PF04982.13 KZN91072.1 - 1.5e-42 144.6 7.8 1.5e-42 144.6 7.8 3.9 3 0 0 3 3 3 2 HPP family FUSC_2 PF13515.6 KZN91072.1 - 5.8e-10 39.4 15.4 5.8e-10 39.4 15.4 5.2 5 1 0 5 5 5 1 Fusaric acid resistance protein-like APH PF01636.23 KZN91074.1 - 8.2e-10 39.0 0.0 1.5e-09 38.2 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family AA_permease PF00324.21 KZN91075.1 - 3.9e-114 381.9 41.3 4.5e-114 381.7 41.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KZN91075.1 - 1.2e-38 133.1 48.3 1.6e-38 132.7 48.3 1.1 1 0 0 1 1 1 1 Amino acid permease S-methyl_trans PF02574.16 KZN91076.1 - 2e-57 195.0 0.0 2.3e-57 194.8 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase CAP59_mtransfer PF11735.8 KZN91077.1 - 1.6e-88 296.4 0.0 2e-88 296.1 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF1772 PF08592.11 KZN91079.1 - 2.3e-05 24.7 0.2 3.2e-05 24.2 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) adh_short_C2 PF13561.6 KZN91080.1 - 6.3e-40 137.2 0.4 2.2e-38 132.1 0.4 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN91080.1 - 3e-29 101.9 1.0 1.1e-28 100.0 1.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN91080.1 - 6.6e-08 32.7 0.6 1.7e-07 31.4 0.2 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KZN91080.1 - 0.019 14.4 0.1 1.8 8.0 0.1 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KZN91080.1 - 0.049 12.8 0.1 0.066 12.3 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KZN91080.1 - 0.095 13.0 0.2 0.17 12.1 0.2 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF4056 PF13265.6 KZN91080.1 - 0.21 10.9 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4056) CorA PF01544.18 KZN91081.1 - 1.2 8.3 4.2 2.1 7.6 4.2 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HIP1_clath_bdg PF16515.5 KZN91081.1 - 5.6 7.6 9.1 0.63 10.7 2.6 2.4 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 RabGAP-TBC PF00566.18 KZN91084.1 - 3.6e-48 164.1 0.0 5.8e-48 163.4 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 KZN91084.1 - 2.5e-05 24.1 0.0 5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 GRAM domain EF-hand_6 PF13405.6 KZN91084.1 - 0.0062 16.4 0.2 0.025 14.5 0.2 2.1 1 0 0 1 1 1 1 EF-hand domain CNH PF00780.22 KZN91085.1 - 5.9e-66 222.9 0.0 9.7e-66 222.2 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KZN91085.1 - 2.3e-35 122.5 0.3 4.4e-35 121.6 0.3 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 KZN91085.1 - 2e-13 50.6 0.0 6.4e-13 49.0 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KZN91085.1 - 0.018 15.6 0.0 0.057 13.9 0.0 1.8 2 0 0 2 2 2 0 PH domain Fungal_trans PF04082.18 KZN91086.1 - 1.4e-06 27.6 0.3 2.6e-06 26.7 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain dbPDZ_assoc PF16610.5 KZN91086.1 - 0.87 9.8 3.4 0.3 11.3 0.2 1.8 2 0 0 2 2 2 0 Unstructured region between two PDZ domains on Dlg5 2OG-FeII_Oxy_2 PF13532.6 KZN91087.1 - 1.6e-32 113.3 0.0 3.1e-32 112.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SHOCT PF09851.9 KZN91087.1 - 0.00072 19.2 0.9 0.0015 18.2 0.9 1.6 1 0 0 1 1 1 1 Short C-terminal domain AMP-binding PF00501.28 KZN91088.1 - 1.2e-76 258.0 0.0 1.5e-76 257.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KZN91088.1 - 9.5e-15 55.3 0.2 2.3e-14 54.1 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WD40 PF00400.32 KZN91089.1 - 3.7e-13 49.7 7.0 0.74 10.8 0.0 7.9 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN91089.1 - 2.5e-05 24.5 0.0 0.017 15.4 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain NDUF_B12 PF08122.12 KZN91090.1 - 1.4e-28 98.7 1.7 2.3e-28 98.0 1.7 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family CAF1 PF04857.20 KZN91091.1 - 1.3e-22 80.4 0.0 2.3e-11 43.4 0.0 2.1 2 0 0 2 2 2 2 CAF1 family ribonuclease Cu_amine_oxid PF01179.20 KZN91092.1 - 9.7e-158 525.4 0.0 1.2e-157 525.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KZN91092.1 - 2.6e-23 82.3 1.5 4.8e-22 78.3 0.1 2.5 1 1 1 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KZN91092.1 - 2.8e-14 53.1 0.0 5.2e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain TPR_2 PF07719.17 KZN91093.1 - 5.2e-10 38.7 7.8 7.4e-05 22.6 0.3 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KZN91093.1 - 1.2e-09 37.6 5.1 0.0017 18.1 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KZN91093.1 - 2.9e-07 30.7 5.1 0.00036 20.8 0.1 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KZN91093.1 - 2.9e-05 24.5 1.1 0.0059 17.1 0.0 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KZN91093.1 - 5.7e-05 22.9 2.2 1.1 9.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KZN91093.1 - 9.6e-05 22.3 7.1 0.0016 18.5 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KZN91093.1 - 0.00017 22.2 4.3 0.31 11.7 1.2 3.0 1 1 0 2 2 2 2 Tetratricopeptide repeat Cas9_a PF18470.1 KZN91093.1 - 0.0006 19.4 0.0 0.00079 19.0 0.0 1.2 1 0 0 1 1 1 1 Cas9 alpha-helical lobe domain ANAPC3 PF12895.7 KZN91093.1 - 0.0023 18.1 0.2 0.0065 16.7 0.1 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.6 KZN91093.1 - 0.0042 16.6 0.4 0.0062 16.0 0.4 1.2 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP MIT PF04212.18 KZN91093.1 - 0.0097 16.0 1.2 0.22 11.6 0.4 2.4 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 KZN91093.1 - 0.017 14.8 3.2 0.77 9.5 0.4 3.6 3 0 0 3 3 3 0 TPR repeat TPR_6 PF13174.6 KZN91093.1 - 0.037 14.7 3.5 0.16 12.7 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 KZN91093.1 - 0.086 12.9 0.6 1.3 9.1 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KZN91093.1 - 0.11 12.4 4.2 2.3 8.2 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KZN91093.1 - 0.18 12.7 0.1 0.18 12.7 0.1 3.8 4 1 0 4 4 3 0 Tetratricopeptide repeat MARVEL PF01284.23 KZN91094.1 - 9e-08 32.3 2.7 1.6e-07 31.5 2.7 1.3 1 0 0 1 1 1 1 Membrane-associating domain DGF-1_C PF11040.8 KZN91094.1 - 0.081 12.9 0.4 0.081 12.9 0.4 1.9 2 1 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Methyltransf_3 PF01596.17 KZN91095.1 - 6.7e-15 54.8 0.0 2.1e-14 53.2 0.0 1.7 1 1 1 2 2 2 1 O-methyltransferase Methyltransf_24 PF13578.6 KZN91095.1 - 1.4e-12 48.6 0.0 2.6e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 KZN91095.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase GFO_IDH_MocA PF01408.22 KZN91096.1 - 9.7e-26 91.0 0.1 1.7e-25 90.2 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KZN91096.1 - 3.8e-12 46.3 0.0 6.3e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KZN91096.1 - 0.00023 21.8 0.0 0.00046 20.8 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 KZN91096.1 - 0.00042 20.4 0.1 0.00069 19.7 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus OCD_Mu_crystall PF02423.15 KZN91096.1 - 0.012 14.6 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family HPP PF04982.13 KZN91098.1 - 1.6e-36 125.2 8.2 1.6e-36 125.2 8.2 1.8 2 0 0 2 2 2 1 HPP family ABC_tran PF00005.27 KZN91099.1 - 9.3e-45 152.5 0.0 1.1e-21 77.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KZN91099.1 - 3e-21 75.2 1.5 3e-21 75.2 1.5 2.7 4 0 0 4 4 2 1 ABC transporter AAA_21 PF13304.6 KZN91099.1 - 5.1e-18 65.9 0.8 0.00016 21.6 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KZN91099.1 - 2.4e-10 40.2 0.3 0.17 11.3 0.0 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KZN91099.1 - 2.1e-08 34.9 1.5 0.058 13.9 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KZN91099.1 - 1.1e-07 31.4 0.4 0.0038 16.9 0.0 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 KZN91099.1 - 1.8e-06 28.0 0.1 0.042 13.5 0.0 2.8 3 0 0 3 3 3 2 AAA ATPase domain AAA_28 PF13521.6 KZN91099.1 - 1.8e-05 25.0 0.0 0.0085 16.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KZN91099.1 - 2.2e-05 24.9 0.0 0.4 11.1 0.0 3.6 4 1 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KZN91099.1 - 2.7e-05 24.6 0.1 0.096 13.1 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KZN91099.1 - 3.5e-05 23.9 0.1 0.024 14.7 0.0 3.1 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KZN91099.1 - 4.3e-05 23.8 0.0 0.19 12.0 0.1 2.8 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KZN91099.1 - 4.9e-05 23.9 0.0 0.11 13.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KZN91099.1 - 7.8e-05 22.6 4.4 0.0052 16.7 0.1 3.0 4 0 0 4 4 3 1 RsgA GTPase AAA_5 PF07728.14 KZN91099.1 - 9.5e-05 22.4 0.1 0.37 10.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KZN91099.1 - 0.00013 22.3 0.9 2.2 8.7 0.0 3.8 4 0 0 4 4 4 2 RNA helicase NB-ARC PF00931.22 KZN91099.1 - 0.0003 20.1 0.0 0.81 8.8 0.0 3.2 3 0 0 3 3 3 1 NB-ARC domain NACHT PF05729.12 KZN91099.1 - 0.00054 19.9 0.3 0.8 9.6 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_24 PF13479.6 KZN91099.1 - 0.00071 19.4 0.3 1.8 8.3 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KZN91099.1 - 0.00083 19.5 1.3 0.1 12.7 0.0 3.2 4 0 0 4 4 2 1 AAA domain Roc PF08477.13 KZN91099.1 - 0.0056 16.9 0.5 5.4 7.2 0.0 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 KZN91099.1 - 0.0058 16.7 0.0 6.2 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 KZN91099.1 - 0.0059 16.2 0.3 4.1 6.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 KZN91099.1 - 0.009 15.5 0.0 1.9 8.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 KZN91099.1 - 0.012 15.1 0.0 1.1 8.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 KZN91099.1 - 0.02 14.5 0.0 0.21 11.2 0.0 2.6 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.15 KZN91099.1 - 0.056 13.4 0.2 3.5 7.5 0.1 2.5 2 0 0 2 2 2 0 NTPase Rad17 PF03215.15 KZN91099.1 - 0.1 12.5 0.0 16 5.4 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_30 PF13604.6 KZN91099.1 - 0.12 12.1 2.2 4.2 7.0 0.0 3.3 4 0 0 4 4 3 0 AAA domain DUF2813 PF11398.8 KZN91099.1 - 0.13 11.5 1.1 17 4.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) FeoB_N PF02421.18 KZN91099.1 - 0.14 11.7 0.0 4.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B ATPase_2 PF01637.18 KZN91099.1 - 0.17 11.8 0.4 27 4.5 0.0 2.8 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea Dynamin_N PF00350.23 KZN91099.1 - 0.2 11.7 3.4 34 4.4 0.0 3.7 3 1 1 4 4 4 0 Dynamin family AAA_17 PF13207.6 KZN91099.1 - 0.23 11.9 0.8 34 4.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 KZN91099.1 - 0.31 11.1 3.0 22 5.1 0.1 3.1 3 1 0 3 3 3 0 Helicase HerA, central domain DUF3584 PF12128.8 KZN91099.1 - 2.5 5.5 7.0 0.23 8.9 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) UQ_con PF00179.26 KZN91101.1 - 7.1e-43 145.6 0.1 2.9e-42 143.6 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Cyclin_C_2 PF16899.5 KZN91101.1 - 1.9e-33 115.0 0.0 4.8e-30 104.0 0.0 2.6 2 0 0 2 2 2 2 Cyclin C-terminal domain UBA_3 PF09288.10 KZN91101.1 - 1.1e-05 25.1 0.0 2.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Cyclin_N PF00134.23 KZN91101.1 - 2.5e-05 24.0 0.0 4.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Prok-E2_B PF14461.6 KZN91101.1 - 0.0014 18.3 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B NESP55 PF06390.12 KZN91101.1 - 0.0091 15.6 0.3 0.022 14.4 0.3 1.5 1 0 0 1 1 1 1 Neuroendocrine-specific golgi protein P55 (NESP55) DUF1421 PF07223.11 KZN91101.1 - 0.032 14.1 0.1 0.07 13.0 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain (DUF1421) AAA PF00004.29 KZN91102.1 - 3.3e-40 137.6 0.0 6e-40 136.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KZN91102.1 - 2.6e-10 39.9 0.5 4.8e-10 39.1 0.5 1.4 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KZN91102.1 - 1.3e-09 37.8 0.1 2.4e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 KZN91102.1 - 1.1e-05 25.7 0.2 0.018 15.3 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.14 KZN91102.1 - 1.6e-05 25.1 0.0 3.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KZN91102.1 - 2e-05 23.9 0.0 3.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KZN91102.1 - 6e-05 23.1 0.0 0.00018 21.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KZN91102.1 - 0.00046 20.6 0.4 0.0067 16.8 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KZN91102.1 - 0.00067 19.4 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KZN91102.1 - 0.0064 16.7 1.5 0.0074 16.5 0.0 1.9 3 0 0 3 3 1 1 AAA domain AAA_18 PF13238.6 KZN91102.1 - 0.011 16.3 0.1 0.03 14.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain PhoH PF02562.16 KZN91102.1 - 0.015 14.8 0.6 0.52 9.7 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.6 KZN91102.1 - 0.016 15.4 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KZN91102.1 - 0.019 14.7 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 KZN91102.1 - 0.02 14.7 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KZN91102.1 - 0.024 13.8 0.1 0.057 12.6 0.0 1.6 2 0 0 2 2 2 0 TIP49 P-loop domain ATPase PF06745.13 KZN91102.1 - 0.034 13.5 0.1 0.51 9.6 0.1 2.2 1 1 1 2 2 2 0 KaiC AAA_14 PF13173.6 KZN91102.1 - 0.035 14.1 0.0 0.069 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KZN91102.1 - 0.049 14.0 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KZN91102.1 - 0.061 12.7 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KZN91102.1 - 0.071 13.0 0.2 0.65 9.9 0.1 2.2 1 1 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 KZN91102.1 - 0.089 12.1 0.1 0.2 10.9 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 KZN91102.1 - 0.091 12.3 0.1 0.4 10.2 0.1 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 KZN91102.1 - 0.12 12.0 0.3 0.46 10.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain Prot_ATP_OB_N PF17758.1 KZN91102.1 - 0.15 11.7 0.5 1 9.0 0.0 2.4 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain DUF2075 PF09848.9 KZN91102.1 - 0.2 10.9 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KZN91102.1 - 0.27 10.9 2.0 0.33 10.6 0.3 2.1 2 1 0 2 2 2 0 AAA domain WD40 PF00400.32 KZN91103.1 - 5.9e-16 58.6 14.4 6.5e-06 26.8 0.7 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN91103.1 - 0.0021 18.3 0.0 0.3 11.4 0.0 3.2 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PBP1_TM PF14812.6 KZN91103.1 - 0.28 11.6 5.5 0.94 9.9 5.5 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 KZN91103.1 - 0.54 10.7 9.2 1.1 9.7 9.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KZN91103.1 - 2.3 7.5 7.6 3.4 6.9 7.6 1.2 1 0 0 1 1 1 0 NOA36 protein Mg_trans_NIPA PF05653.14 KZN91104.1 - 2.5e-60 204.1 9.1 1.8e-56 191.4 7.7 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KZN91104.1 - 6.3e-05 23.2 0.6 6.3e-05 23.2 0.6 3.2 3 1 0 3 3 3 1 EamA-like transporter family DUF2569 PF10754.9 KZN91104.1 - 3.9 7.9 9.3 0.83 10.1 4.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) Glyco_hydro_3 PF00933.21 KZN91105.1 - 9.5e-63 212.5 0.0 1.4e-62 212.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KZN91105.1 - 5.5e-53 180.0 1.0 7.5e-53 179.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KZN91105.1 - 3.6e-22 78.3 0.3 3.6e-22 78.3 0.3 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain Sugar-bind PF04198.13 KZN91105.1 - 0.018 14.2 0.1 0.034 13.3 0.1 1.4 1 0 0 1 1 1 0 Putative sugar-binding domain DUF1735 PF08522.10 KZN91105.1 - 0.097 13.3 0.5 0.22 12.1 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1735) fn3_5 PF06280.12 KZN91105.1 - 0.16 12.7 0.9 0.36 11.5 0.9 1.6 1 0 0 1 1 1 0 Fn3-like domain FlaC_arch PF05377.11 KZN91106.1 - 0.047 14.1 3.0 0.061 13.7 0.5 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 KZN91106.1 - 0.073 12.8 3.6 1.2 9.0 3.5 2.4 2 0 0 2 2 2 0 Septum formation initiator Med21 PF11221.8 KZN91106.1 - 0.13 12.5 0.3 0.13 12.5 0.3 3.2 3 1 0 3 3 2 0 Subunit 21 of Mediator complex DUF4140 PF13600.6 KZN91106.1 - 0.22 11.9 2.9 0.24 11.8 0.2 2.5 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Lebercilin PF15619.6 KZN91106.1 - 0.25 11.0 5.8 0.59 9.8 1.1 2.4 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DivIVA PF05103.13 KZN91106.1 - 0.71 10.0 4.6 1.7 8.7 1.2 2.4 2 0 0 2 2 2 0 DivIVA protein Rootletin PF15035.6 KZN91106.1 - 0.87 9.6 8.6 5.7 6.9 8.7 2.1 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion YabA PF06156.13 KZN91106.1 - 1.1 9.9 5.3 5.1 7.8 0.5 2.5 2 0 0 2 2 2 0 Initiation control protein YabA ABC_tran_CTD PF16326.5 KZN91106.1 - 1.2 9.4 9.9 1.3 9.3 3.9 2.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain GAS PF13851.6 KZN91106.1 - 1.4 8.2 8.5 0.22 10.9 2.3 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DASH_Spc19 PF08287.11 KZN91106.1 - 1.9 8.4 6.8 2 8.3 0.3 3.1 3 0 0 3 3 3 0 Spc19 DHR10 PF18595.1 KZN91106.1 - 7.3 6.7 13.5 0.35 11.0 6.3 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain MAD PF05557.13 KZN91106.1 - 8.8 4.6 9.0 2.3 6.5 3.2 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein VASt PF16016.5 KZN91107.1 - 2.1e-34 119.2 0.0 4.1e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KZN91107.1 - 2.2e-22 79.1 0.0 3.7e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 GRAM domain FAD_binding_4 PF01565.23 KZN91108.1 - 4.8e-27 94.4 0.7 7.6e-27 93.7 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KZN91108.1 - 3e-09 36.8 0.0 6.7e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF3309 PF11752.8 KZN91108.1 - 0.18 11.9 0.0 0.66 10.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3309) Trypan_PARP PF05887.11 KZN91109.1 - 0.96 9.4 32.5 0.67 9.9 10.5 3.0 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) Sugar_tr PF00083.24 KZN91111.1 - 1.7e-65 221.7 24.4 1.9e-65 221.5 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN91111.1 - 1.2e-14 54.0 33.7 1.5e-14 53.7 25.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_P21 PF05313.12 KZN91111.1 - 0.014 15.0 1.8 0.026 14.1 1.8 1.4 1 0 0 1 1 1 0 Poxvirus P21 membrane protein Thioredoxin PF00085.20 KZN91112.1 - 1.1e-27 96.0 0.1 1.4e-27 95.6 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KZN91112.1 - 2.7e-08 34.0 0.1 7.6e-07 29.4 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KZN91112.1 - 1.4e-07 31.9 0.1 1e-06 29.2 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KZN91112.1 - 4.3e-06 26.7 0.0 5.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KZN91112.1 - 4.3e-06 26.5 0.4 0.00071 19.3 0.1 2.1 1 1 1 2 2 2 2 Redoxin OST3_OST6 PF04756.13 KZN91112.1 - 5.2e-05 22.7 0.1 7e-05 22.3 0.0 1.4 1 1 1 2 2 2 1 OST3 / OST6 family, transporter family TraF PF13728.6 KZN91112.1 - 0.00011 22.1 0.1 0.00013 21.9 0.1 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 KZN91112.1 - 0.00067 19.4 0.0 0.0008 19.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 KZN91112.1 - 0.0019 18.3 0.1 0.0046 17.1 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_6 PF13848.6 KZN91112.1 - 0.002 18.0 0.0 0.0026 17.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.6 KZN91112.1 - 0.0041 17.3 0.5 2.1 8.5 0.0 2.8 1 1 2 3 3 3 2 Thioredoxin Thioredoxin_5 PF13743.6 KZN91112.1 - 0.0045 16.7 0.1 0.045 13.4 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin DSBA PF01323.20 KZN91112.1 - 0.0076 16.0 1.2 1.7 8.3 0.1 2.2 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Glutaredoxin PF00462.24 KZN91112.1 - 0.014 15.6 0.1 0.022 15.0 0.1 1.5 1 0 0 1 1 1 0 Glutaredoxin HyaE PF07449.11 KZN91112.1 - 0.034 14.1 0.1 0.048 13.6 0.1 1.3 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE SIMPL PF04402.14 KZN91113.1 - 1.5e-27 97.4 1.5 2e-27 96.9 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF541) DUF948 PF06103.11 KZN91113.1 - 0.19 12.0 0.6 0.68 10.2 0.1 2.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) HMA PF00403.26 KZN91115.1 - 9.5e-10 38.8 0.5 1.2e-09 38.5 0.5 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain ABC2_membrane PF01061.24 KZN91116.1 - 1.5e-80 269.6 56.4 1.3e-42 145.6 14.7 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KZN91116.1 - 1.9e-36 125.6 0.1 2e-17 64.0 0.0 2.9 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 KZN91116.1 - 8.2e-27 92.9 1.0 6.7e-21 74.0 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KZN91116.1 - 4.9e-14 52.7 0.2 1.8e-13 50.9 0.1 2.1 2 0 0 2 2 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KZN91116.1 - 1.4e-06 28.8 0.2 0.02 15.3 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain AAA_18 PF13238.6 KZN91116.1 - 7.4e-06 26.5 0.0 0.0015 19.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KZN91116.1 - 3.1e-05 24.1 0.1 0.013 15.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KZN91116.1 - 3.5e-05 23.8 0.0 0.026 14.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KZN91116.1 - 0.00011 21.9 0.3 0.0086 15.7 0.1 2.7 3 0 0 3 3 3 1 AAA domain ABC2_membrane_3 PF12698.7 KZN91116.1 - 0.00013 21.2 44.2 0.015 14.5 13.2 2.6 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_29 PF13555.6 KZN91116.1 - 0.00026 20.7 0.4 0.011 15.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KZN91116.1 - 0.00079 19.4 0.2 0.0027 17.6 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 KZN91116.1 - 0.0036 17.6 0.1 0.077 13.2 0.2 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KZN91116.1 - 0.005 17.3 0.0 0.69 10.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KZN91116.1 - 0.012 15.9 0.0 0.49 10.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KZN91116.1 - 0.02 14.6 1.2 2.3 7.9 0.2 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KZN91116.1 - 0.043 13.7 0.6 7.2 6.5 0.2 2.4 2 0 0 2 2 2 0 NACHT domain SMC_N PF02463.19 KZN91116.1 - 0.045 13.2 0.0 0.61 9.5 0.0 2.5 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 KZN91116.1 - 0.056 13.0 2.5 0.29 10.7 0.6 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MbeD_MobD PF04899.12 KZN91116.1 - 0.12 12.5 0.2 0.32 11.2 0.2 1.7 1 0 0 1 1 1 0 MbeD/MobD like PduV-EutP PF10662.9 KZN91116.1 - 0.15 11.8 0.5 8.4 6.1 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 KZN91116.1 - 0.22 11.9 0.4 16 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KZN91116.1 - 0.33 11.4 0.1 0.33 11.4 0.1 3.3 4 0 0 4 4 2 0 AAA domain DUF4246 PF14033.6 KZN91117.1 - 5.1e-138 461.0 0.0 6.1e-138 460.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Thioredoxin PF00085.20 KZN91118.1 - 3.8e-24 84.6 0.0 5.1e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 KZN91118.1 - 0.0028 17.6 0.0 0.041 13.8 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KZN91118.1 - 0.004 17.4 0.0 0.0071 16.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 KZN91118.1 - 0.0052 16.7 0.0 0.0064 16.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 KZN91118.1 - 0.028 14.6 0.0 0.037 14.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like Fungal_trans PF04082.18 KZN91120.1 - 7.7e-11 41.5 5.7 6.7e-10 38.4 5.7 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_2_C PF02836.17 KZN91121.1 - 1.6e-100 336.1 0.0 3.3e-100 335.1 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KZN91121.1 - 1.1e-59 202.0 0.0 4.1e-59 200.1 0.0 1.9 2 0 0 2 2 2 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 KZN91121.1 - 4.5e-51 173.1 0.6 9.6e-51 172.0 0.6 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 KZN91121.1 - 3.7e-15 56.2 1.7 1.6e-12 47.8 0.1 2.7 2 0 0 2 2 2 2 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 KZN91121.1 - 3.9e-12 46.8 0.4 1.1e-11 45.3 0.4 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 DUF4660 PF15559.6 KZN91121.1 - 0.015 15.6 0.0 0.042 14.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4660) Sugar_tr PF00083.24 KZN91122.1 - 1.5e-86 291.0 31.6 1.7e-86 290.9 31.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN91122.1 - 1.3e-07 30.9 41.3 5.9e-07 28.7 41.1 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Folate_carrier PF01770.18 KZN91122.1 - 0.0016 17.3 4.1 0.017 13.9 0.7 2.2 1 1 1 2 2 2 2 Reduced folate carrier DUF3382 PF11862.8 KZN91122.1 - 0.73 10.2 9.0 3.3 8.0 0.6 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF3382) MFS_1 PF07690.16 KZN91123.1 - 4.5e-33 114.6 25.8 7.9e-33 113.8 25.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KZN91123.1 - 3.4e-07 29.9 11.3 7.3e-06 25.5 11.3 2.0 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF4499 PF14934.6 KZN91123.1 - 0.25 11.7 3.7 0.41 11.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4499) Tfb2_C PF18307.1 KZN91124.1 - 0.2 12.1 0.0 0.52 10.8 0.0 1.6 1 0 0 1 1 1 0 Transcription factor Tfb2 (p52) C-terminal domain Mito_carr PF00153.27 KZN91126.1 - 9.2e-48 160.1 10.8 6.4e-16 58.0 0.2 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein HMD PF03201.16 KZN91126.1 - 0.13 12.5 0.1 0.83 9.9 0.0 2.4 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Fungal_trans PF04082.18 KZN91127.1 - 6.5e-27 94.2 0.5 1.3e-26 93.3 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain PrpF PF04303.13 KZN91128.1 - 2.8e-78 263.5 2.7 6.1e-77 259.1 2.7 2.0 1 1 0 1 1 1 1 PrpF protein DUF4397 PF14344.6 KZN91128.1 - 0.017 15.9 0.0 0.05 14.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4397) 2OG-Fe_Oxy_2 PF10014.9 KZN91128.1 - 0.089 12.6 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 2OG-Fe dioxygenase MFS_1 PF07690.16 KZN91129.1 - 4.1e-35 121.4 14.7 5.1e-35 121.0 14.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KZN91129.1 - 1.8e-09 37.4 2.5 1.8e-09 37.4 2.5 1.9 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 KZN91129.1 - 1.8e-09 37.0 3.9 2.5e-09 36.5 3.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1772 PF08592.11 KZN91129.1 - 6.3 7.1 8.9 0.37 11.1 1.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Ribosomal_L19 PF01245.20 KZN91130.1 - 1.9e-15 56.8 1.9 3.4e-15 55.9 1.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 PriA_3primeBD PF17764.1 KZN91130.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 3′ DNA-binding domain (3′BD) GatD_N PF18195.1 KZN91130.1 - 0.16 11.3 0.1 0.27 10.6 0.1 1.3 1 0 0 1 1 1 0 GatD N-terminal domain AMP-binding PF00501.28 KZN91132.1 - 1.5e-13 50.2 0.1 1.3e-07 30.6 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme NPCC PF08058.11 KZN91133.1 - 1.9e-24 86.2 0.0 2.8e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore complex component CytochromB561_N PF09786.9 KZN91133.1 - 0.00054 19.1 1.5 0.00063 18.9 1.5 1.1 1 0 0 1 1 1 1 Cytochrome B561, N terminal MASE1 PF05231.14 KZN91133.1 - 0.15 11.2 0.6 0.22 10.6 0.6 1.2 1 0 0 1 1 1 0 MASE1 Dynein_AAA_lid PF17852.1 KZN91133.1 - 0.17 11.9 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain Hid1 PF12722.7 KZN91134.1 - 0 1118.1 0.0 0 1118.0 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KZN91134.1 - 6.5e-100 335.4 0.0 7.3e-100 335.2 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein HAT_KAT11 PF08214.11 KZN91137.1 - 2e-106 356.2 0.0 3.3e-106 355.5 0.0 1.3 1 0 0 1 1 1 1 Histone acetylation protein Glyco_transf_21 PF13506.6 KZN91138.1 - 1.8e-13 50.3 0.1 4.9e-06 26.1 0.0 3.4 1 1 1 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KZN91138.1 - 0.0017 18.3 0.0 0.0037 17.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KZN91138.1 - 0.0051 16.6 0.0 0.014 15.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Ank_2 PF12796.7 KZN91139.1 - 4.4e-14 52.8 0.5 2.6e-13 50.4 0.6 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KZN91139.1 - 8.5e-12 45.0 1.3 1.4e-07 31.6 0.1 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KZN91139.1 - 2e-10 40.7 1.5 1.5e-08 34.7 0.6 2.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KZN91139.1 - 2.6e-09 37.4 0.4 8.5e-09 35.8 0.1 2.1 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN91139.1 - 5e-09 35.7 0.0 4.6e-06 26.6 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat WW PF00397.26 KZN91140.1 - 7.8e-11 41.9 2.7 1.8e-10 40.7 2.7 1.6 1 0 0 1 1 1 1 WW domain WRW PF10206.9 KZN91140.1 - 0.082 13.3 1.3 0.81 10.1 0.6 2.3 2 0 0 2 2 2 0 Mitochondrial F1F0-ATP synthase, subunit f CFEM PF05730.11 KZN91141.1 - 7e-05 22.9 5.0 7e-05 22.9 5.0 3.0 4 0 0 4 4 4 1 CFEM domain Tme5_EGF_like PF09064.10 KZN91141.1 - 0.11 12.5 2.4 0.43 10.5 2.4 2.0 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like Hydrophobin PF01185.18 KZN91142.1 - 1.9e-09 38.0 6.5 2.6e-09 37.6 6.5 1.2 1 0 0 1 1 1 1 Fungal hydrophobin NMO PF03060.15 KZN91144.1 - 3.4e-54 184.4 1.1 5.3e-53 180.6 1.1 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KZN91144.1 - 6.2e-14 51.8 0.0 1.2e-11 44.2 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KZN91144.1 - 1.7e-05 24.1 0.6 2.8e-05 23.3 0.6 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 KZN91144.1 - 0.016 14.7 0.3 0.22 10.9 0.0 2.2 1 1 0 2 2 2 0 Histidine biosynthesis protein NanE PF04131.14 KZN91144.1 - 0.022 13.9 0.1 0.04 13.1 0.1 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Glu_synthase PF01645.17 KZN91144.1 - 0.044 12.9 0.5 0.11 11.6 0.5 1.7 1 1 0 1 1 1 0 Conserved region in glutamate synthase Sdh_cyt PF01127.22 KZN91145.1 - 1.2e-25 89.9 5.2 1.6e-25 89.5 5.2 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Ribonucleas_3_3 PF14622.6 KZN91146.1 - 2.1e-28 99.1 0.0 3.8e-28 98.2 0.0 1.4 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KZN91146.1 - 1e-06 29.3 0.0 2.9e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain Adap_comp_sub PF00928.21 KZN91147.1 - 2.6e-91 305.7 0.0 4.8e-91 304.8 0.0 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KZN91147.1 - 1e-08 35.2 0.2 1.6e-08 34.6 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KZN91147.1 - 0.11 11.9 0.0 0.31 10.4 0.0 1.7 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Gtr1_RagA PF04670.12 KZN91148.1 - 5.4e-95 317.2 0.3 6.4e-95 316.9 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KZN91148.1 - 6.9e-09 36.0 0.0 1.4e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KZN91148.1 - 2e-08 33.9 0.0 2.7e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KZN91148.1 - 2.9e-08 33.5 0.0 4.4e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KZN91148.1 - 3.8e-07 30.2 0.0 6.8e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 KZN91148.1 - 0.00063 19.7 0.1 0.0014 18.6 0.1 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain G-alpha PF00503.20 KZN91148.1 - 0.00081 18.6 2.0 0.65 9.1 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit DUF815 PF05673.13 KZN91148.1 - 0.0095 15.1 0.1 0.019 14.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 KZN91148.1 - 0.013 15.3 0.3 0.058 13.1 0.2 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KZN91148.1 - 0.018 15.6 0.0 0.036 14.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 KZN91148.1 - 0.036 14.0 0.3 0.37 10.7 0.0 2.6 3 0 0 3 3 3 0 RsgA GTPase AAA_7 PF12775.7 KZN91148.1 - 0.11 11.9 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AIG1 PF04548.16 KZN91148.1 - 0.32 10.3 1.4 0.46 9.8 0.4 1.9 2 1 0 2 2 2 0 AIG1 family DUF1688 PF07958.11 KZN91149.1 - 3.4e-183 609.2 0.0 3.8e-183 609.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) NapE PF06796.11 KZN91150.1 - 0.081 12.5 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE TPR_2 PF07719.17 KZN91151.1 - 0.00028 20.8 0.3 0.57 10.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat UBA PF00627.31 KZN91151.1 - 0.0023 17.8 0.9 0.0041 17.0 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain TPR_1 PF00515.28 KZN91151.1 - 0.0037 17.0 0.1 8.4 6.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KZN91151.1 - 0.0082 16.4 0.1 0.071 13.4 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat DnaJ PF00226.31 KZN91151.1 - 0.064 13.4 0.0 0.22 11.7 0.0 1.9 1 0 0 1 1 1 0 DnaJ domain GCD14 PF08704.10 KZN91152.1 - 5e-60 203.2 0.3 2.1e-59 201.2 0.0 2.2 2 1 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit AdoHcyase PF05221.17 KZN91152.1 - 0.044 12.9 0.0 0.074 12.2 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase tRNA-synt_1e PF01406.19 KZN91153.1 - 2.9e-114 381.5 0.0 5.1e-114 380.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KZN91153.1 - 8.1e-07 28.1 0.6 0.011 14.5 0.1 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.11 KZN91153.1 - 0.0037 17.7 0.1 0.0037 17.7 0.1 2.2 2 0 0 2 2 2 1 DALR domain TAL_FSA PF00923.19 KZN91154.1 - 1.8e-47 162.1 0.1 2.4e-47 161.7 0.1 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase PQ-loop PF04193.14 KZN91155.1 - 2.2e-40 136.2 11.4 5.7e-21 74.1 2.1 2.6 2 0 0 2 2 2 2 PQ loop repeat DUF2165 PF09933.9 KZN91155.1 - 0.084 12.9 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) HTH_Bact PF18768.1 KZN91155.1 - 0.31 10.6 1.8 0.44 10.1 0.0 2.1 3 0 0 3 3 3 0 Helix-turn-helix bacterial domain SGS PF05002.15 KZN91157.1 - 2.3e-28 98.1 2.9 2.3e-28 98.1 2.9 2.0 2 0 0 2 2 2 1 SGS domain CS PF04969.16 KZN91157.1 - 3e-16 60.2 0.1 5.1e-16 59.4 0.1 1.4 1 0 0 1 1 1 1 CS domain TPR_1 PF00515.28 KZN91157.1 - 0.0006 19.5 3.4 0.23 11.4 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KZN91157.1 - 0.0017 18.3 6.5 0.99 9.7 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KZN91157.1 - 0.0038 17.5 5.0 0.45 10.8 1.8 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KZN91157.1 - 0.053 13.6 1.0 0.24 11.5 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KZN91157.1 - 0.37 11.5 9.1 3.8 8.2 0.3 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat SQHop_cyclase_C PF13243.6 KZN91158.1 - 2.7e-50 171.3 0.5 4.7e-48 163.9 0.4 2.6 2 1 1 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KZN91158.1 - 1.5e-44 152.3 3.7 1.3e-40 139.3 0.2 3.5 2 1 1 3 3 3 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 KZN91158.1 - 2.7e-34 116.6 8.9 1.5e-10 40.6 0.4 4.5 4 0 0 4 4 4 4 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 KZN91158.1 - 0.00011 21.7 0.2 0.55 9.5 0.1 3.6 2 1 1 3 3 3 2 Pectic acid lyase TP6A_N PF04406.14 KZN91159.1 - 3.4e-18 65.4 0.2 6e-18 64.6 0.2 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase UQ_con PF00179.26 KZN91160.1 - 7.4e-50 168.2 0.0 8.4e-50 168.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Scramblase PF03803.15 KZN91161.1 - 1.4e-55 188.0 2.7 1.3e-29 103.1 0.1 3.0 1 1 0 2 2 2 2 Scramblase Ribosomal_L27 PF01016.19 KZN91163.1 - 2.6e-28 97.9 0.0 4.1e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal L27 protein Sacchrp_dh_NADP PF03435.18 KZN91163.1 - 0.16 12.2 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GMC_oxred_N PF00732.19 KZN91164.1 - 1.6e-52 178.8 0.0 2e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KZN91164.1 - 9.5e-43 146.2 0.0 1.8e-42 145.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KZN91164.1 - 5.6e-06 25.7 0.5 0.0011 18.2 0.5 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KZN91164.1 - 8.7e-06 25.2 0.2 6.3e-05 22.3 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KZN91164.1 - 2.6e-05 24.0 0.1 0.00093 18.9 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KZN91164.1 - 2.7e-05 24.3 0.6 8e-05 22.8 0.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KZN91164.1 - 0.0053 15.9 0.1 0.0085 15.2 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 KZN91164.1 - 0.0054 15.5 0.1 0.037 12.7 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KZN91164.1 - 0.02 14.0 0.3 0.02 14.0 0.3 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KZN91164.1 - 0.052 12.8 0.3 9.6 5.4 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KZN91164.1 - 0.084 12.1 0.1 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 KZN91164.1 - 0.11 11.3 0.2 0.17 10.7 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase 3HCDH_N PF02737.18 KZN91164.1 - 0.23 11.3 0.5 0.46 10.3 0.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 KZN91164.1 - 0.25 10.6 1.6 0.28 10.5 0.6 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase Ysc84 PF04366.12 KZN91165.1 - 4.4e-39 133.2 0.6 6.5e-39 132.6 0.6 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator Rad9_Rad53_bind PF08605.10 KZN91168.1 - 1e-29 103.3 0.0 1.6e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding Tudor_3 PF18115.1 KZN91168.1 - 8.2e-19 67.2 0.1 1.6e-18 66.2 0.1 1.5 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain BRCT PF00533.26 KZN91168.1 - 3.3e-08 33.8 0.0 2.5e-07 31.0 0.0 2.5 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KZN91168.1 - 6.9e-08 32.8 0.0 4.4e-07 30.2 0.0 2.4 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KZN91168.1 - 0.0014 18.5 0.0 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 KZN91168.1 - 0.13 12.3 0.0 4.8 7.3 0.0 2.5 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain tRNA_int_endo PF01974.17 KZN91169.1 - 1e-19 70.4 0.5 3.5e-19 68.6 0.5 1.8 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KZN91169.1 - 6.8e-06 25.7 0.0 0.004 16.8 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Nop10p PF04135.12 KZN91170.1 - 1.2e-22 79.6 0.5 1.5e-22 79.4 0.5 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family PIN_6 PF17146.4 KZN91171.1 - 2.3e-30 104.9 0.1 8.4e-30 103.1 0.0 2.0 2 0 0 2 2 2 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 KZN91171.1 - 2.9e-30 104.2 3.9 5.3e-30 103.4 3.9 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_15 PF17032.5 KZN91171.1 - 0.032 15.0 0.4 0.064 14.0 0.4 1.5 1 0 0 1 1 1 0 zinc-ribbon family zf-NADH-PPase PF09297.11 KZN91171.1 - 0.12 12.0 2.3 0.4 10.4 0.4 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain ACC_epsilon PF13822.6 KZN91171.1 - 4.8 7.9 5.8 3 8.6 2.1 2.4 1 1 1 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Myb_DNA-binding PF00249.31 KZN91172.1 - 0.078 13.2 0.2 3.4 7.9 0.2 2.8 3 0 0 3 3 3 0 Myb-like DNA-binding domain DUF3995 PF13160.6 KZN91172.1 - 1.7 9.0 12.2 2.8 8.3 2.8 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3995) Peptidase_M18 PF02127.15 KZN91173.1 - 9.4e-136 453.0 0.0 1.1e-135 452.8 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KZN91173.1 - 0.066 12.2 0.1 2.1 7.3 0.0 2.4 3 0 0 3 3 3 0 M42 glutamyl aminopeptidase ADH_N PF08240.12 KZN91174.1 - 1.5e-27 95.6 1.8 1.5e-27 95.6 1.8 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 KZN91174.1 - 2.4e-05 24.1 2.1 2.8e-05 23.9 0.6 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 KZN91174.1 - 0.003 17.1 0.4 0.022 14.3 0.0 2.2 3 0 0 3 3 3 1 Glucose dehydrogenase C-terminus Hap4_Hap_bind PF10297.9 KZN91175.1 - 1.1e-08 34.8 6.9 1.1e-08 34.8 6.9 2.6 3 0 0 3 3 3 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 KZN91175.1 - 5.2e-07 29.7 8.0 9.3e-06 25.7 8.7 2.1 1 1 1 2 2 2 1 bZIP transcription factor Filament PF00038.21 KZN91175.1 - 0.023 14.3 3.6 0.037 13.6 3.6 1.3 1 0 0 1 1 1 0 Intermediate filament protein bZIP_Maf PF03131.17 KZN91175.1 - 0.031 14.8 2.6 0.098 13.2 2.6 1.8 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF812 PF05667.11 KZN91175.1 - 0.033 13.1 1.9 0.048 12.5 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FAM184 PF15665.5 KZN91175.1 - 0.037 13.8 1.8 0.058 13.2 1.8 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B dsrm PF00035.26 KZN91175.1 - 0.11 13.2 0.0 0.29 11.9 0.0 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif bZIP_2 PF07716.15 KZN91175.1 - 0.16 12.1 11.1 0.34 11.0 10.7 1.7 1 1 0 1 1 1 0 Basic region leucine zipper DUF2353 PF09789.9 KZN91175.1 - 0.18 11.1 2.6 0.26 10.6 2.6 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) LRRFIP PF09738.9 KZN91175.1 - 0.88 9.0 5.9 1.3 8.4 5.9 1.2 1 0 0 1 1 1 0 LRRFIP family SRP54 PF00448.22 KZN91176.1 - 5.4e-75 251.4 3.1 9.8e-75 250.5 3.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KZN91176.1 - 4.3e-29 101.0 0.4 4.3e-29 101.0 0.4 4.1 3 1 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 KZN91176.1 - 1.2e-19 70.3 0.6 3e-19 69.0 0.6 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 KZN91176.1 - 1.3e-07 31.4 0.2 3.8e-07 29.9 0.2 1.8 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KZN91176.1 - 6.4e-06 26.4 0.4 2.2e-05 24.6 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KZN91176.1 - 1.6e-05 25.3 1.5 2.9e-05 24.5 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KZN91176.1 - 2.2e-05 24.9 0.0 4.7e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KZN91176.1 - 0.00023 20.5 0.1 0.00056 19.3 0.1 1.6 1 0 0 1 1 1 1 Zeta toxin MeaB PF03308.16 KZN91176.1 - 0.00023 20.2 3.9 0.00025 20.1 0.3 2.7 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KZN91176.1 - 0.00087 19.1 0.6 0.0035 17.1 0.6 2.1 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KZN91176.1 - 0.001 19.0 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase CbiA PF01656.23 KZN91176.1 - 0.0022 18.0 0.0 0.0048 17.0 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ResIII PF04851.15 KZN91176.1 - 0.004 17.2 0.7 0.01 15.9 0.7 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit 6PF2K PF01591.18 KZN91176.1 - 0.0044 16.3 0.0 0.0079 15.5 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase ATP_bind_1 PF03029.17 KZN91176.1 - 0.0048 16.7 0.6 0.014 15.1 0.1 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 KZN91176.1 - 0.0051 16.3 1.4 1.6 8.1 1.0 3.0 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KZN91176.1 - 0.0054 17.0 0.0 0.017 15.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KZN91176.1 - 0.0061 16.6 0.3 0.068 13.3 0.2 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KZN91176.1 - 0.0068 17.0 0.0 0.018 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KZN91176.1 - 0.007 16.6 0.1 0.015 15.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KZN91176.1 - 0.0078 15.9 0.1 0.027 14.1 0.1 1.9 1 0 0 1 1 1 1 Thymidylate kinase MobB PF03205.14 KZN91176.1 - 0.0098 15.8 0.0 0.032 14.1 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_31 PF13614.6 KZN91176.1 - 0.03 14.2 0.4 0.25 11.2 0.2 2.2 1 1 1 2 2 2 0 AAA domain MipZ PF09140.11 KZN91176.1 - 0.036 13.4 0.7 0.65 9.2 0.7 2.3 1 1 0 1 1 1 0 ATPase MipZ Arf PF00025.21 KZN91176.1 - 0.088 12.3 0.0 0.26 10.7 0.0 1.8 2 0 0 2 2 1 0 ADP-ribosylation factor family AAA_24 PF13479.6 KZN91176.1 - 0.095 12.4 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KZN91176.1 - 0.11 13.0 0.7 0.46 11.0 0.0 2.2 2 1 0 2 2 2 0 ABC transporter Torsin PF06309.11 KZN91176.1 - 0.15 12.2 0.1 0.63 10.1 0.0 1.9 2 0 0 2 2 2 0 Torsin GET2 PF08690.10 KZN91176.1 - 0.84 9.3 6.6 1.6 8.4 6.6 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 Rrp15p PF07890.12 KZN91177.1 - 3.3e-36 124.6 5.9 3.3e-36 124.6 5.9 1.7 2 1 0 2 2 2 1 Rrp15p DUF1373 PF07117.11 KZN91177.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1373) Fer2 PF00111.27 KZN91178.1 - 5.7e-14 51.8 1.0 7.9e-14 51.4 1.0 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain YcgR_2 PF12945.7 KZN91178.1 - 0.11 12.6 0.0 1.3 9.2 0.0 2.3 2 1 1 3 3 3 0 Flagellar protein YcgR Mito_carr PF00153.27 KZN91179.1 - 4.3e-10 39.4 7.6 0.0049 16.8 0.1 5.0 3 2 0 3 3 3 3 Mitochondrial carrier protein PhoD PF09423.10 KZN91180.1 - 1.1e-36 126.6 0.0 2.4e-36 125.5 0.0 1.5 1 1 0 1 1 1 1 PhoD-like phosphatase Pur_ac_phosph_N PF16656.5 KZN91180.1 - 0.00035 21.1 0.4 0.00089 19.8 0.4 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain fn3 PF00041.21 KZN91180.1 - 0.062 13.7 0.4 0.17 12.3 0.3 1.9 1 1 0 1 1 1 0 Fibronectin type III domain PhoD_N PF16655.5 KZN91180.1 - 0.13 12.8 0.3 0.41 11.2 0.3 1.9 1 1 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain Glyco_hydro_18 PF00704.28 KZN91181.1 - 4.5e-15 56.2 0.0 7.8e-15 55.4 0.0 1.3 1 1 0 2 2 2 1 Glycosyl hydrolases family 18 KGG PF10685.9 KZN91182.1 - 6.2e-16 58.1 12.6 4.5e-08 33.1 1.6 3.2 2 1 1 3 3 3 3 Stress-induced bacterial acidophilic repeat motif DUF5551 PF17705.1 KZN91182.1 - 0.039 13.6 0.1 0.052 13.2 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5551) FPP PF05911.11 KZN91183.1 - 0.0001 20.7 1.9 0.0001 20.7 1.9 2.7 2 1 0 2 2 2 1 Filament-like plant protein, long coiled-coil Fez1 PF06818.15 KZN91183.1 - 0.00085 19.8 14.4 0.00085 19.8 14.4 4.5 3 1 1 4 4 4 2 Fez1 APG6_N PF17675.1 KZN91183.1 - 0.0053 17.3 4.0 0.0053 17.3 4.0 6.4 3 2 1 4 4 4 1 Apg6 coiled-coil region Metal_resist PF13801.6 KZN91183.1 - 0.015 15.5 6.3 0.015 15.5 6.3 6.2 5 2 3 8 8 8 0 Heavy-metal resistance RMMBL PF07521.12 KZN91183.1 - 0.035 14.0 0.0 0.13 12.2 0.0 2.0 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain FOXP-CC PF16159.5 KZN91183.1 - 0.55 10.9 0.1 0.55 10.9 0.1 4.7 2 1 0 4 4 4 0 FOXP coiled-coil domain Internalin_N PF12354.8 KZN91184.1 - 8.8 6.5 6.4 4.3 7.5 0.1 3.4 4 0 0 4 4 4 0 Bacterial adhesion/invasion protein N terminal Fungal_trans PF04082.18 KZN91185.1 - 5e-19 68.4 0.0 8.2e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane PF01061.24 KZN91186.1 - 9.7e-88 293.1 56.5 4e-47 160.3 24.4 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KZN91186.1 - 1.9e-38 132.1 0.1 1.8e-18 67.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KZN91186.1 - 3.2e-36 123.1 7.0 1.5e-33 114.5 0.0 3.9 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KZN91186.1 - 8.3e-19 68.0 0.1 1.9e-18 66.8 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KZN91186.1 - 2.9e-06 27.8 0.2 0.0019 18.6 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KZN91186.1 - 4.1e-06 26.8 0.1 0.0051 16.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 KZN91186.1 - 6.8e-06 25.8 0.1 7.2e-05 22.4 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KZN91186.1 - 0.00028 21.4 0.1 0.042 14.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KZN91186.1 - 0.00051 19.7 2.6 0.028 14.2 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain dNK PF01712.19 KZN91186.1 - 0.0018 18.2 0.0 0.76 9.6 0.0 2.4 2 0 0 2 2 2 1 Deoxynucleoside kinase ABC2_membrane_3 PF12698.7 KZN91186.1 - 0.0023 17.1 45.6 0.015 14.4 19.5 2.8 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KZN91186.1 - 0.0029 17.5 0.4 2.8 7.7 0.1 2.7 3 0 0 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KZN91186.1 - 0.0032 17.9 0.7 0.91 10.0 0.0 3.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 KZN91186.1 - 0.0034 16.9 0.0 0.43 10.0 0.0 3.3 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 KZN91186.1 - 0.004 17.3 0.0 0.36 11.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KZN91186.1 - 0.005 16.8 3.2 3.7 7.5 0.2 3.4 3 0 0 3 3 3 2 NACHT domain AAA_17 PF13207.6 KZN91186.1 - 0.0098 16.3 0.4 2.9 8.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KZN91186.1 - 0.018 14.8 0.1 2.9 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain PDR_assoc PF08370.11 KZN91186.1 - 0.025 14.3 2.3 0.3 10.9 0.6 2.8 2 0 0 2 2 2 0 Plant PDR ABC transporter associated cobW PF02492.19 KZN91186.1 - 0.04 13.5 1.0 0.97 9.0 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 KZN91186.1 - 0.09 12.5 0.1 4.6 6.9 0.0 2.6 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_22 PF13401.6 KZN91186.1 - 0.098 12.9 3.3 1.1 9.6 0.1 3.0 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.23 KZN91186.1 - 0.1 12.7 0.3 34 4.6 0.1 3.0 3 0 0 3 3 3 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 KZN91186.1 - 0.17 12.3 0.1 13 6.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Viral_helicase1 PF01443.18 KZN91186.1 - 0.22 11.2 0.2 14 5.4 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 KZN91186.1 - 0.24 11.7 0.4 3.4 7.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain Abhydrolase_3 PF07859.13 KZN91187.1 - 5.3e-67 225.8 0.0 7.3e-67 225.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KZN91187.1 - 2e-11 43.7 0.0 3.1e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 KZN91187.1 - 3.8e-08 32.6 0.3 1.1e-07 31.1 0.3 1.7 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 KZN91187.1 - 1e-05 24.6 0.0 2.4e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Steryl acetyl hydrolase Ribonuc_L-PSP PF01042.21 KZN91188.1 - 1.7e-38 131.3 0.0 1.8e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF2529 PF10740.9 KZN91188.1 - 0.11 12.2 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2529) DsbB PF02600.16 KZN91188.1 - 0.12 12.8 0.1 0.18 12.3 0.1 1.2 1 0 0 1 1 1 0 Disulfide bond formation protein DsbB Sugar_tr PF00083.24 KZN91189.1 - 5.8e-87 292.4 18.6 6.7e-87 292.2 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN91189.1 - 1.4e-11 43.9 20.4 1.4e-11 43.9 20.4 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 KZN91189.1 - 0.0047 17.4 1.0 0.0047 17.4 1.0 2.4 3 0 0 3 3 3 1 Phage holin family 2 DUF1593 PF07632.11 KZN91190.1 - 3.5e-89 298.7 0.0 4.4e-89 298.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) MFS_1 PF07690.16 KZN91191.1 - 2.3e-19 69.6 29.7 2.3e-19 69.6 29.7 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Abhydrolase_2 PF02230.16 KZN91192.1 - 1.7e-19 70.5 0.0 5.4e-13 49.2 0.1 2.1 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase APH PF01636.23 KZN91193.1 - 7.1e-06 26.1 0.5 0.042 13.8 0.1 2.6 2 1 0 2 2 2 2 Phosphotransferase enzyme family Glyco_hydro_18 PF00704.28 KZN91194.1 - 1.9e-19 70.5 0.1 5.7e-19 69.0 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CoA_transf_3 PF02515.17 KZN91195.1 - 3.3e-67 227.2 0.0 1.3e-66 225.2 0.0 1.7 1 1 0 1 1 1 1 CoA-transferase family III GMC_oxred_N PF00732.19 KZN91196.1 - 2.8e-58 197.7 0.0 3.7e-58 197.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KZN91196.1 - 7.7e-33 114.0 0.0 2.2e-32 112.6 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KZN91196.1 - 0.00029 21.0 0.0 0.00071 19.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KZN91196.1 - 0.0042 16.2 0.1 0.059 12.4 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KZN91196.1 - 0.023 13.9 0.1 0.1 11.8 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KZN91196.1 - 0.024 13.7 0.0 0.054 12.6 0.0 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KZN91196.1 - 0.031 13.5 0.2 0.12 11.6 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aminotran_3 PF00202.21 KZN91198.1 - 7.2e-80 268.6 0.0 8.8e-80 268.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III NmrA PF05368.13 KZN91199.1 - 2.4e-36 125.5 0.0 3.7e-35 121.6 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KZN91199.1 - 1.1e-15 58.1 0.0 1.5e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KZN91199.1 - 1.3e-06 28.1 0.0 1.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KZN91199.1 - 2.2e-06 26.9 0.0 3.2e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KZN91199.1 - 0.0029 16.8 0.0 0.0041 16.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Fungal_trans PF04082.18 KZN91201.1 - 4.6e-16 58.7 1.2 1.9e-15 56.6 1.2 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN91201.1 - 1.6e-05 24.9 9.5 2.7e-05 24.2 9.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KZN91202.1 - 6.3e-12 45.1 23.7 6.3e-12 45.1 23.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KZN91202.1 - 4.4e-06 26.5 1.3 4.4e-06 26.5 1.3 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 KZN91202.1 - 0.00035 19.6 5.5 0.00035 19.6 5.5 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter SDF PF00375.18 KZN91202.1 - 0.018 14.1 0.0 0.034 13.2 0.0 1.5 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family Transketolase_N PF00456.21 KZN91203.1 - 1.7e-14 53.5 1.0 4.2e-13 48.9 1.0 2.2 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 KZN91203.1 - 7.2e-12 45.3 0.0 1.7e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 KZN91203.1 - 3.7e-06 26.7 0.4 1.5e-05 24.7 0.1 2.1 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.21 KZN91203.1 - 0.00016 21.5 0.8 0.00098 18.9 0.8 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 KZN91203.1 - 0.00082 18.4 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Phosphatase PF15698.5 KZN91203.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Phosphatase Glyco_hydro_30 PF02055.16 KZN91204.1 - 9.3e-33 113.6 3.5 1.3e-32 113.1 3.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 KZN91204.1 - 1.8e-09 37.7 0.5 4.1e-09 36.5 0.5 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 KZN91204.1 - 0.00033 20.0 2.1 0.0009 18.6 0.1 2.1 1 1 0 2 2 2 1 Glycosyl hydrolase family 59 Gly_transf_sug PF04488.15 KZN91205.1 - 1.3e-13 51.4 0.2 3e-13 50.2 0.2 1.8 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif MFS_1 PF07690.16 KZN91207.1 - 8.6e-35 120.3 33.6 8.6e-35 120.3 33.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF63 PF01889.17 KZN91207.1 - 0.34 11.1 6.4 0.039 14.1 1.7 1.9 2 0 0 2 2 2 0 Membrane protein of unknown function DUF63 WCOR413 PF05562.11 KZN91207.1 - 4.4 7.2 6.8 0.21 11.5 0.2 2.2 3 0 0 3 3 3 0 Cold acclimation protein WCOR413 RNA_pol_I_A49 PF06870.12 KZN91208.1 - 6.9e-67 226.0 0.0 3.3e-66 223.8 0.0 1.8 1 1 0 1 1 1 1 A49-like RNA polymerase I associated factor Aminotran_1_2 PF00155.21 KZN91209.1 - 8.8e-87 291.6 0.0 1.1e-86 291.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KZN91209.1 - 1.5e-06 27.1 0.0 2.5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KZN91209.1 - 0.00012 21.5 0.1 0.00031 20.2 0.1 1.6 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KZN91209.1 - 0.0004 19.5 0.0 0.00071 18.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KZN91209.1 - 0.0081 15.5 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Usp PF00582.26 KZN91210.1 - 8.3e-21 75.0 1.2 3.2e-19 69.8 1.2 2.6 1 1 0 1 1 1 1 Universal stress protein family ATP-synt_ab PF00006.25 KZN91211.1 - 9.3e-69 231.3 0.0 1.2e-68 230.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KZN91211.1 - 3.2e-12 46.8 0.1 6.2e-12 45.9 0.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Trp_syntA PF00290.20 KZN91212.1 - 1.1e-95 319.4 0.0 2.1e-95 318.4 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 KZN91212.1 - 1e-51 176.1 1.2 1.6e-51 175.4 1.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF5595 PF18077.1 KZN91214.1 - 0.07 13.2 0.2 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) ADH_zinc_N PF00107.26 KZN91215.1 - 2.9e-23 82.3 0.3 5e-23 81.5 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KZN91215.1 - 1.1e-10 42.7 0.0 2.3e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KZN91215.1 - 0.001 18.9 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KZN91215.1 - 0.02 14.3 0.9 0.037 13.5 0.9 1.4 1 0 0 1 1 1 0 short chain dehydrogenase GYF PF02213.16 KZN91217.1 - 1.2e-18 66.5 0.4 2.5e-18 65.5 0.4 1.6 1 0 0 1 1 1 1 GYF domain Homeodomain PF00046.29 KZN91217.1 - 0.41 10.5 2.6 1.4 8.8 2.6 1.9 1 0 0 1 1 1 0 Homeodomain MIP PF00230.20 KZN91220.1 - 3.7e-53 180.6 8.5 4.6e-53 180.2 8.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein FGGY_C PF02782.16 KZN91221.1 - 6.8e-73 244.6 0.6 1.3e-72 243.7 0.6 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KZN91221.1 - 2.8e-66 223.6 0.0 4.2e-66 223.0 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KZN91221.1 - 0.041 13.4 0.6 5.1 6.5 0.0 2.7 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family DUF2089 PF09862.9 KZN91221.1 - 0.12 12.5 0.1 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) DUF2625 PF10946.8 KZN91221.1 - 0.12 11.4 0.0 0.27 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF2625 p450 PF00067.22 KZN91222.1 - 1.7e-60 205.1 0.0 2.2e-60 204.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-CCCH_2 PF14608.6 KZN91223.1 - 3.9e-11 43.0 61.1 0.00024 21.4 13.3 5.4 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 KZN91223.1 - 0.0013 19.0 0.0 0.0021 18.3 0.0 1.3 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) CDK2AP PF09806.9 KZN91223.1 - 0.12 12.5 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Amino_oxidase PF01593.24 KZN91224.1 - 3.5e-36 125.5 0.0 4.9e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KZN91224.1 - 3.1e-14 53.0 3.0 2.5e-13 50.1 0.0 3.1 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KZN91224.1 - 2.5e-08 33.9 0.0 5.5e-06 26.2 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KZN91224.1 - 0.00048 19.6 0.2 0.0013 18.1 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KZN91224.1 - 0.017 13.8 0.0 0.28 9.8 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 KZN91224.1 - 0.024 13.7 0.2 0.062 12.4 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 KZN91224.1 - 0.024 13.9 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KZN91224.1 - 0.062 12.4 0.1 0.28 10.2 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KZN91224.1 - 0.077 12.2 0.0 0.42 9.8 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KZN91224.1 - 0.19 12.3 0.0 3.5 8.3 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mago-bind PF09282.10 KZN91225.1 - 1.4e-14 53.6 4.3 2.5e-14 52.8 4.3 1.4 1 0 0 1 1 1 1 Mago binding UCR_UQCRX_QCR9 PF05365.12 KZN91226.1 - 4e-24 84.3 2.8 5.4e-24 83.9 2.8 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF4203 PF13886.6 KZN91226.1 - 0.03 14.0 0.0 0.033 13.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) zf-UBR PF02207.20 KZN91227.1 - 7.2e-19 67.7 15.0 1.8e-18 66.4 15.0 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KZN91227.1 - 0.00073 19.3 0.0 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.6 KZN91227.1 - 0.0051 17.1 1.1 0.0051 17.1 1.1 4.4 4 1 1 5 5 5 1 Ring finger domain zf-RING_5 PF14634.6 KZN91227.1 - 0.0063 16.4 0.9 0.0063 16.4 0.9 3.9 3 1 1 4 4 4 1 zinc-RING finger domain Nop14 PF04147.12 KZN91227.1 - 0.42 8.8 4.5 0.7 8.0 4.5 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 KZN91227.1 - 0.62 8.1 10.2 1.1 7.3 10.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 KZN91227.1 - 2.6 7.3 4.9 5 6.4 4.9 1.3 1 0 0 1 1 1 0 BUD22 YL1 PF05764.13 KZN91227.1 - 7.3 6.6 11.4 0.41 10.7 5.4 1.8 2 0 0 2 2 2 0 YL1 nuclear protein RED_N PF07808.13 KZN91228.1 - 5.6e-08 32.6 1.2 1.4e-07 31.3 1.2 1.7 1 0 0 1 1 1 1 RED-like protein N-terminal region GvpG PF05120.12 KZN91228.1 - 0.88 9.6 4.8 0.19 11.7 0.4 2.2 2 0 0 2 2 2 0 Gas vesicle protein G DUF3788 PF12663.7 KZN91229.1 - 0.083 12.9 1.6 29 4.7 0.0 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF3788) CSN8_PSD8_EIF3K PF10075.9 KZN91229.1 - 2.6 8.0 6.7 9.2 6.2 0.6 2.2 1 1 1 2 2 2 0 CSN8/PSMD8/EIF3K family AKAP7_NLS PF10469.9 KZN91230.1 - 1.3e-17 64.4 0.0 2e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Sec6 PF06046.13 KZN91231.1 - 2.7e-170 567.6 10.8 2.7e-170 567.6 10.8 1.4 2 0 0 2 2 2 1 Exocyst complex component Sec6 LprI PF07007.12 KZN91231.1 - 0.12 13.0 2.2 0.3 11.8 0.5 2.6 2 0 0 2 2 2 0 Lysozyme inhibitor LprI Vps53_N PF04100.12 KZN91231.1 - 0.81 8.6 10.1 0.44 9.5 1.8 2.4 2 0 0 2 2 2 0 Vps53-like, N-terminal HEAT_2 PF13646.6 KZN91231.1 - 1.4 9.4 5.4 1.7 9.1 0.2 3.9 4 1 0 4 4 4 0 HEAT repeats PEP-utilisers_N PF05524.13 KZN91231.1 - 1.6 8.9 4.9 6.2 7.0 3.2 3.0 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal Ribosomal_L30 PF00327.20 KZN91232.1 - 7.3e-16 57.8 0.2 9.4e-16 57.4 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Pyridoxal_deC PF00282.19 KZN91233.1 - 4.4e-19 68.4 0.0 7e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KZN91233.1 - 8.7e-09 34.8 0.0 7.1e-08 31.8 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KZN91233.1 - 2.3e-06 27.1 0.0 3.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KZN91233.1 - 0.0012 18.3 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KZN91233.1 - 0.035 12.7 0.0 0.29 9.6 0.0 2.0 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme HMGL-like PF00682.19 KZN91234.1 - 4.2e-79 265.8 0.6 6.1e-79 265.3 0.6 1.2 1 0 0 1 1 1 1 HMGL-like DUF3666 PF12408.8 KZN91234.1 - 0.58 9.4 2.8 0.47 9.7 0.3 2.1 2 0 0 2 2 2 0 Ribose-5-phosphate isomerase NAD_binding_2 PF03446.15 KZN91236.1 - 7.6e-31 107.4 0.0 1.1e-30 106.9 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KZN91236.1 - 3.5e-21 75.7 0.0 5.5e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KZN91236.1 - 0.0005 20.6 0.0 0.0011 19.5 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 KZN91236.1 - 0.0058 15.6 0.0 0.008 15.2 0.0 1.1 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family PTH2 PF01981.16 KZN91237.1 - 6.9e-42 142.4 0.1 9.2e-42 142.0 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 GOLD_2 PF13897.6 KZN91237.1 - 0.098 13.2 0.3 0.15 12.6 0.3 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking SART-1 PF03343.13 KZN91238.1 - 3e-193 643.9 63.4 3.4e-193 643.7 63.4 1.0 1 0 0 1 1 1 1 SART-1 family Aminotran_1_2 PF00155.21 KZN91239.1 - 1.6e-92 310.5 0.0 1.9e-92 310.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF155 PF02582.14 KZN91240.1 - 2.1e-52 177.8 0.0 3.5e-52 177.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 PEP_mutase PF13714.6 KZN91242.1 - 6.5e-69 232.0 7.7 7.3e-69 231.8 7.7 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Hydrolase_6 PF13344.6 KZN91242.1 - 0.11 12.6 0.1 0.33 11.1 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KZN91243.1 - 2.8e-18 66.6 0.0 4e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KZN91243.1 - 2.3e-07 31.3 0.0 0.00014 22.2 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KZN91243.1 - 1.6e-05 24.9 0.0 3.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like APH PF01636.23 KZN91244.1 - 3.5e-17 63.1 0.0 9.3e-17 61.8 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 KZN91244.1 - 0.022 13.9 0.0 0.2 10.8 0.0 2.0 2 0 0 2 2 2 0 Fructosamine kinase Haspin_kinase PF12330.8 KZN91244.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF1679 PF07914.11 KZN91244.1 - 0.13 11.1 0.1 0.86 8.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EcKinase PF02958.20 KZN91244.1 - 0.16 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Vps54 PF07928.12 KZN91245.1 - 5.9e-46 156.2 2.1 1.3e-45 155.1 0.1 2.7 3 0 0 3 3 3 1 Vps54-like protein Vps54_N PF10475.9 KZN91245.1 - 1.3e-06 27.9 0.6 1.3e-06 27.9 0.6 3.0 3 0 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex zf-C2H2 PF00096.26 KZN91246.1 - 7.4e-19 67.1 28.2 3.5e-05 24.0 1.7 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KZN91246.1 - 1e-18 66.8 28.7 1.4e-06 28.5 1.5 5.6 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KZN91246.1 - 2.9e-10 40.1 25.5 0.004 17.9 1.3 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KZN91246.1 - 8.5e-06 25.9 2.5 0.5 10.7 0.1 4.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KZN91246.1 - 0.00088 19.6 15.0 0.012 16.0 0.3 4.1 4 0 0 4 4 4 1 Zinc-finger of C2H2 type FOXP-CC PF16159.5 KZN91246.1 - 0.0064 17.1 11.0 0.23 12.1 0.8 3.7 3 1 1 4 4 4 2 FOXP coiled-coil domain zf_UBZ PF18439.1 KZN91246.1 - 0.013 15.1 2.3 1.1 8.9 0.2 2.8 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 KZN91246.1 - 0.019 14.7 0.8 0.019 14.7 0.8 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 KZN91246.1 - 0.021 14.9 1.1 2.9 8.0 0.1 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger Yippee-Mis18 PF03226.14 KZN91246.1 - 0.28 11.4 1.7 17 5.7 0.1 2.3 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF4764 PF15961.5 KZN91246.1 - 0.88 8.2 6.9 0.065 11.9 0.4 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4764) LIM PF00412.22 KZN91246.1 - 2.8 8.2 5.7 26 5.1 0.1 3.0 2 1 1 3 3 3 0 LIM domain HNH PF01844.23 KZN91246.1 - 7 6.9 8.4 7.8 6.8 0.1 3.8 4 0 0 4 4 4 0 HNH endonuclease zf-CRD PF17979.1 KZN91246.1 - 9.8 6.3 8.7 3.7 7.6 1.8 2.2 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions Fringe PF02434.16 KZN91247.1 - 1.2e-09 38.1 0.0 2.2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.12 KZN91247.1 - 2.7e-07 30.3 0.1 7.3e-07 28.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF604 SRP_TPR_like PF17004.5 KZN91248.1 - 5.6e-22 78.0 4.1 1.2e-20 73.6 1.9 2.4 2 0 0 2 2 2 1 Putative TPR-like repeat SRP72 PF08492.12 KZN91248.1 - 2.1e-17 63.3 3.3 2.1e-17 63.3 3.3 2.5 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.6 KZN91248.1 - 1.1e-06 29.1 23.5 0.14 12.7 1.3 7.7 5 2 2 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 KZN91248.1 - 7.6e-05 22.5 10.6 2.7 8.3 0.1 6.1 6 0 0 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KZN91248.1 - 9.1e-05 22.6 11.1 1.8 8.9 4.2 4.2 4 1 0 4 4 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KZN91248.1 - 0.00016 21.6 4.9 8.8 6.8 0.1 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KZN91248.1 - 0.00017 22.1 22.0 15 6.8 0.1 8.7 7 2 3 10 10 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 KZN91248.1 - 0.049 13.7 7.9 6.9 6.9 0.2 5.6 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 KZN91248.1 - 0.05 13.9 8.3 4.9 7.6 0.0 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat HHH_8 PF14716.6 KZN91248.1 - 0.056 13.8 0.3 7.1 7.1 0.5 3.5 3 0 0 3 3 3 0 Helix-hairpin-helix domain PPR PF01535.20 KZN91248.1 - 0.13 12.6 0.9 27 5.3 0.0 4.1 5 0 0 5 5 4 0 PPR repeat SPOB_a PF14689.6 KZN91248.1 - 0.28 10.9 0.9 1.5 8.6 0.2 2.6 3 0 0 3 3 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain Cytochrom_B562 PF07361.11 KZN91248.1 - 0.91 10.2 6.1 5.2 7.8 2.3 3.1 2 0 0 2 2 2 0 Cytochrome b562 TPR_6 PF13174.6 KZN91248.1 - 1.4 9.7 9.2 52 4.8 0.3 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KZN91248.1 - 4.8 7.2 11.8 3.5 7.6 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat GFO_IDH_MocA PF01408.22 KZN91249.1 - 4.6e-15 56.5 0.0 7.4e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KZN91249.1 - 0.00038 21.1 0.1 0.00077 20.1 0.1 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 KZN91249.1 - 0.019 15.4 0.0 0.033 14.6 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Sugar_tr PF00083.24 KZN91250.1 - 4.6e-38 131.2 30.0 5e-26 91.6 10.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KZN91250.1 - 1.3e-31 109.8 52.1 2.7e-22 79.2 31.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4229 PF14012.6 KZN91250.1 - 0.21 11.7 8.1 1.4 9.1 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) DUF4131 PF13567.6 KZN91250.1 - 1.6 8.3 4.8 7.4 6.2 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PhyH PF05721.13 KZN91251.1 - 1.6e-19 71.0 0.0 2.2e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KZN91251.1 - 0.0081 16.6 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase vWA-TerF-like PF10138.9 KZN91253.1 - 9e-05 22.7 0.0 0.00013 22.1 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 KZN91253.1 - 0.16 12.2 0.1 0.68 10.2 0.1 1.9 1 1 0 1 1 1 0 von Willebrand factor type A domain PhoLip_ATPase_C PF16212.5 KZN91254.1 - 1.1e-69 234.9 21.4 1.1e-69 234.9 21.4 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KZN91254.1 - 1.7e-23 82.0 4.3 7.4e-23 80.0 1.0 2.7 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KZN91254.1 - 7.9e-13 49.2 2.6 3.3e-06 27.5 0.2 3.7 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KZN91254.1 - 2e-12 47.0 0.0 2e-12 47.0 0.0 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KZN91254.1 - 3.2e-11 43.1 0.0 6.3e-10 39.0 0.0 2.6 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KZN91254.1 - 0.0031 17.3 0.0 0.0095 15.7 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PTB PF08416.13 KZN91254.1 - 0.072 13.2 0.1 2.9 8.1 0.0 2.4 2 0 0 2 2 2 0 Phosphotyrosine-binding domain SPT_ssu-like PF11779.8 KZN91254.1 - 0.11 12.2 3.5 9.8 5.9 0.3 3.2 2 0 0 2 2 2 0 Small subunit of serine palmitoyltransferase-like MFS_1 PF07690.16 KZN91256.1 - 1.4e-29 103.2 60.7 3.4e-25 88.7 38.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN91256.1 - 2.4e-15 56.3 26.5 2.7e-13 49.6 5.2 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter Acetyltransf_3 PF13302.7 KZN91257.1 - 5.8e-08 33.5 0.0 7.3e-08 33.2 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KZN91257.1 - 0.0014 18.8 0.0 0.0017 18.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Phytase PF02333.15 KZN91258.1 - 5e-67 226.5 0.2 2.2e-62 211.2 0.0 2.2 2 0 0 2 2 2 2 Phytase EGF_2 PF07974.13 KZN91258.1 - 0.00011 22.5 12.6 0.00011 22.5 12.6 2.5 2 0 0 2 2 2 1 EGF-like domain EGF_alliinase PF04863.13 KZN91258.1 - 1.1 9.7 15.5 2.1 8.8 2.6 2.9 1 1 1 2 2 2 0 Alliinase EGF-like domain Glyco_transf_8 PF01501.20 KZN91259.1 - 0.012 15.1 0.1 0.46 10.0 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KZN91259.1 - 0.024 14.0 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Aminotran_3 PF00202.21 KZN91260.1 - 7.9e-89 298.1 0.0 1e-88 297.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KZN91260.1 - 0.0001 21.6 0.0 0.00073 18.8 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II TonB_2 PF13103.6 KZN91260.1 - 0.079 13.2 0.0 0.34 11.2 0.0 2.1 2 0 0 2 2 2 0 TonB C terminal Fungal_trans_2 PF11951.8 KZN91261.1 - 3.7e-30 105.0 0.0 4.8e-30 104.6 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Homeodomain PF00046.29 KZN91262.1 - 4.4e-19 68.1 2.3 8.6e-19 67.1 2.3 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KZN91262.1 - 0.0049 16.7 0.7 0.01 15.7 0.7 1.5 1 0 0 1 1 1 1 Homeobox KN domain ANF_receptor PF01094.28 KZN91262.1 - 0.13 11.4 0.8 0.19 10.8 0.8 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region PGP_phosphatase PF09419.10 KZN91263.1 - 1.8e-60 203.4 0.0 2.2e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 KZN91263.1 - 8.4e-05 22.6 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like LcrR PF09621.10 KZN91263.1 - 0.1 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Type III secretion system regulator (LcrR) Hydrolase PF00702.26 KZN91263.1 - 0.18 12.1 0.0 15 5.8 0.0 2.2 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase LSM PF01423.22 KZN91264.1 - 1e-15 57.2 0.4 1.3e-15 56.8 0.4 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KZN91264.1 - 0.059 13.5 0.1 0.11 12.7 0.1 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain Fungal_trans PF04082.18 KZN91265.1 - 2.8e-06 26.6 0.2 5.4e-06 25.6 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_3_C PF01915.22 KZN91266.1 - 2.7e-17 63.4 0.1 4.7e-17 62.6 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain MFS_1 PF07690.16 KZN91268.1 - 2.5e-29 102.3 47.4 2.5e-29 102.3 47.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN91268.1 - 6.3e-07 28.6 14.6 6.3e-07 28.6 14.6 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter Adaptin_binding PF10199.9 KZN91269.1 - 1.3e-19 71.0 2.4 4.3e-19 69.3 2.9 1.6 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 Tom22 PF04281.13 KZN91269.1 - 0.093 12.5 0.3 0.21 11.4 0.3 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 MCU PF04678.13 KZN91270.1 - 2.1e-25 89.9 0.1 4.9e-25 88.6 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Sporozoite_P67 PF05642.11 KZN91270.1 - 0.034 12.3 0.1 0.062 11.4 0.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Hpt PF01627.23 KZN91272.1 - 7.5e-10 38.9 0.0 1.5e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Hpt domain DUF4298 PF14131.6 KZN91272.1 - 0.034 14.1 3.3 0.058 13.4 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) zf-CRD PF17979.1 KZN91272.1 - 0.042 13.9 0.0 0.064 13.4 0.0 1.2 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions NusB PF01029.18 KZN91272.1 - 0.23 11.7 0.1 0.23 11.7 0.1 2.4 2 1 1 3 3 3 0 NusB family GAGA_bind PF06217.12 KZN91272.1 - 0.61 10.3 7.6 0.74 10.1 7.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family PIEZO PF15917.5 KZN91272.1 - 0.71 9.3 8.5 1.6 8.2 8.5 1.6 1 0 0 1 1 1 0 Piezo Presenilin PF01080.17 KZN91272.1 - 1.7 7.3 4.2 1.4 7.6 4.2 1.1 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 KZN91272.1 - 8.1 5.3 9.5 13 4.6 9.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RNA_pol_Rpc4 PF05132.14 KZN91272.1 - 8.7 6.8 11.2 15 6.0 11.2 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 PTPLA PF04387.14 KZN91273.1 - 1.3e-56 190.8 4.6 2.1e-56 190.2 4.6 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Grg1 PF11034.8 KZN91275.1 - 2.8e-30 104.3 12.4 3.2e-30 104.2 12.4 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 HSP9_HSP12 PF04119.12 KZN91275.1 - 0.13 12.7 3.4 0.37 11.2 3.1 1.8 1 1 1 2 2 2 0 Heat shock protein 9/12 APH PF01636.23 KZN91276.1 - 3.7e-20 72.9 0.0 5.9e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family dsrm PF00035.26 KZN91278.1 - 1.6e-05 25.5 0.0 6.8e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KZN91278.1 - 0.011 16.0 0.3 0.026 14.8 0.3 1.7 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Prenyltrans PF00432.21 KZN91279.1 - 4.4e-42 141.5 28.8 1.1e-11 44.3 0.8 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KZN91279.1 - 0.0043 16.2 0.0 0.49 9.4 0.0 2.2 2 0 0 2 2 2 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KZN91279.1 - 0.014 14.5 0.0 0.055 12.6 0.0 1.8 1 1 1 2 2 2 0 Squalene-hopene cyclase C-terminal domain Pea-VEAacid PF08111.11 KZN91279.1 - 0.081 13.3 2.5 1.2 9.6 0.4 2.7 2 0 0 2 2 2 0 Pea-VEAacid family Zn_clus PF00172.18 KZN91280.1 - 0.0031 17.6 7.7 0.0074 16.4 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spectrin PF00435.21 KZN91280.1 - 0.11 13.0 0.1 0.29 11.6 0.1 1.7 1 0 0 1 1 1 0 Spectrin repeat Macoilin PF09726.9 KZN91280.1 - 5.2 5.5 7.3 7.4 5.0 7.3 1.1 1 0 0 1 1 1 0 Macoilin family ubiquitin PF00240.23 KZN91281.1 - 4.4e-135 439.7 20.4 3.3e-33 113.3 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 KZN91281.1 - 6.6e-64 211.7 21.0 2e-15 56.4 0.7 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KZN91281.1 - 8.1e-23 80.7 10.7 0.00043 20.7 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 KZN91281.1 - 1.7e-16 59.9 3.0 0.027 14.4 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KZN91281.1 - 3.9e-15 56.0 8.2 0.028 14.8 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KZN91281.1 - 2.1e-14 53.6 2.6 0.12 12.4 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KZN91281.1 - 5.6e-13 49.4 1.4 0.37 11.4 0.0 4.2 1 1 1 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 KZN91281.1 - 5.2e-11 42.7 0.8 0.52 10.1 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 KZN91281.1 - 3.7e-07 30.1 24.0 16 5.6 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain Methyltrans_RNA PF04452.14 KZN91281.1 - 2.9e-06 26.8 0.4 1.8 7.8 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase DUF3861 PF12977.7 KZN91281.1 - 3.8e-06 27.0 2.5 13 6.1 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 KZN91281.1 - 7.1e-06 26.3 0.0 30 5.1 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) ACT_5 PF13710.6 KZN91281.1 - 1.2e-05 25.0 4.7 10 6.1 0.0 4.3 4 0 0 4 4 4 0 ACT domain Big_7 PF17957.1 KZN91281.1 - 4e-05 24.3 0.1 52 4.7 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig domain UDP-g_GGTase PF06427.11 KZN91281.1 - 0.00014 21.9 4.3 7.1 6.8 0.0 4.0 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 KZN91281.1 - 0.00042 19.8 0.0 23 4.3 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) YcgR_2 PF12945.7 KZN91281.1 - 0.00091 19.3 6.2 29 4.9 0.1 4.3 4 0 0 4 4 4 0 Flagellar protein YcgR DUF493 PF04359.14 KZN91281.1 - 0.003 18.1 0.1 1.4e+02 3.1 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF493) Raf1_HTH PF18579.1 KZN91281.1 - 0.0037 16.9 0.0 1e+02 2.7 0.0 4.1 4 0 0 4 4 4 0 Rubisco accumulation factor 1 helix turn helix domain ACT_4 PF13291.6 KZN91281.1 - 0.0052 17.4 1.0 1.4e+02 3.1 0.0 4.2 4 0 0 4 4 4 0 ACT domain ORF11CD3 PF10549.9 KZN91281.1 - 0.0068 16.5 0.0 91 3.3 0.0 4.3 4 0 0 4 4 4 0 ORF11CD3 domain ProRS-C_2 PF09181.10 KZN91281.1 - 0.11 12.7 5.8 1.1e+02 3.1 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal Baculo_p48 PF04878.13 KZN91281.1 - 0.12 11.2 0.0 61 2.4 0.0 3.0 3 0 0 3 3 3 0 Baculovirus P48 protein Tash_PEST PF07708.11 KZN91281.1 - 0.14 12.4 27.2 6.2 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif Myosin_N PF02736.19 KZN91281.1 - 0.23 11.3 6.3 1.1e+02 2.8 0.0 5.2 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain HAMP_N3 PF18575.1 KZN91281.1 - 0.23 11.0 1.5 2e+02 1.6 0.0 3.9 4 0 0 4 4 4 0 HAMP N-terminal domain 3 PI3K_p85B PF02192.16 KZN91281.1 - 1.9 8.3 9.3 96 2.8 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain BRAP2 PF07576.12 KZN91282.1 - 6.3e-35 119.4 0.0 1.1e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 KZN91282.1 - 3.5e-20 72.1 5.4 1.4e-19 70.2 5.4 2.1 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 KZN91282.1 - 1.5e-08 34.8 9.5 1.5e-08 34.8 9.5 2.6 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KZN91282.1 - 8.4e-06 25.5 10.0 8.4e-06 25.5 10.0 2.1 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KZN91282.1 - 0.0001 22.2 3.1 0.0001 22.2 3.1 2.8 2 1 2 4 4 4 1 RING-type zinc-finger zf-RING_11 PF17123.5 KZN91282.1 - 0.00011 21.9 4.8 0.00011 21.9 4.8 2.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KZN91282.1 - 0.00023 21.0 9.1 0.00023 21.0 9.1 2.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KZN91282.1 - 0.00025 20.9 8.4 0.00025 20.9 8.4 2.8 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KZN91282.1 - 0.00028 20.7 5.6 0.00028 20.7 5.6 2.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KZN91282.1 - 0.00038 20.7 7.5 0.00038 20.7 7.5 2.3 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KZN91282.1 - 0.0026 17.6 2.4 0.0026 17.6 2.4 1.9 2 0 0 2 2 1 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 KZN91282.1 - 0.011 15.8 5.8 0.032 14.3 5.8 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger ZapB PF06005.12 KZN91282.1 - 0.032 14.7 2.6 3.4 8.2 0.0 2.5 1 1 1 2 2 2 0 Cell division protein ZapB TPR_MLP1_2 PF07926.12 KZN91282.1 - 1.1 9.3 10.2 2.6 8.1 10.2 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein zf-HC5HC2H PF13771.6 KZN91282.1 - 1.5 9.1 9.4 7 7.0 2.7 2.7 2 0 0 2 2 2 0 PHD-like zinc-binding domain Prok-RING_4 PF14447.6 KZN91282.1 - 1.8 8.5 24.1 0.19 11.6 9.9 3.5 3 1 1 4 4 3 0 Prokaryotic RING finger family 4 PRKG1_interact PF15898.5 KZN91282.1 - 3.3 8.7 7.3 1.9 9.4 3.2 2.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain zf-C3HC4_4 PF15227.6 KZN91282.1 - 7.9 6.7 12.9 1.4 9.1 5.4 3.4 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING Methyltransf_23 PF13489.6 KZN91283.1 - 9.3e-17 61.3 0.0 1.4e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN91283.1 - 9.4e-12 45.4 0.0 0.00016 22.3 0.0 2.5 1 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KZN91283.1 - 1.2e-10 42.0 0.0 5.3e-10 39.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN91283.1 - 9.7e-10 39.0 0.0 0.00014 22.5 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KZN91283.1 - 4.8e-07 29.7 0.0 7.6e-06 25.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Fungal_trans PF04082.18 KZN91284.1 - 6.3e-11 41.8 0.1 9.1e-11 41.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN91284.1 - 6.5e-09 35.8 11.6 1.4e-08 34.7 11.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_31 PF01055.26 KZN91285.1 - 1.2e-152 509.2 3.3 1.7e-152 508.6 3.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KZN91285.1 - 4.9e-30 104.1 0.1 9.1e-30 103.2 0.1 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KZN91285.1 - 5.3e-05 23.5 0.2 0.00023 21.4 0.2 2.2 1 0 0 1 1 1 1 Galactose mutarotase-like GHL15 PF14885.6 KZN91285.1 - 0.045 13.7 0.3 0.092 12.7 0.3 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 Alpha-amylase PF00128.24 KZN91286.1 - 3.3e-70 237.3 2.9 4.6e-70 236.8 2.9 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KZN91286.1 - 3.5e-30 104.1 0.0 8.9e-30 102.8 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) hDGE_amylase PF14701.6 KZN91286.1 - 0.068 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Zn_clus PF00172.18 KZN91287.1 - 3.7e-06 26.9 8.4 6.9e-06 26.1 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Homeobox_KN PF05920.11 KZN91289.1 - 5.6e-22 77.4 0.2 1.1e-21 76.4 0.2 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KZN91289.1 - 3.1e-07 30.1 0.1 5.5e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 Homeodomain Stevor PF17410.2 KZN91290.1 - 0.8 9.2 2.0 1 8.8 2.0 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame FAD_binding_1 PF00667.20 KZN91291.1 - 2.2e-44 151.6 0.0 3.1e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KZN91291.1 - 7.2e-10 39.5 0.0 1.7e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain AA_permease_2 PF13520.6 KZN91292.1 - 1.8e-55 188.5 46.2 2.3e-55 188.2 46.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN91292.1 - 1.6e-23 83.1 38.3 2.2e-23 82.6 38.3 1.1 1 0 0 1 1 1 1 Amino acid permease Phage_holin_2_1 PF04971.12 KZN91293.1 - 0.12 12.4 0.2 0.49 10.4 0.2 2.0 1 0 0 1 1 1 0 Bacteriophage P21 holin S CstA PF02554.14 KZN91293.1 - 0.67 8.8 11.8 1.5 7.6 11.8 1.6 1 1 0 1 1 1 0 Carbon starvation protein CstA FA_desaturase PF00487.24 KZN91293.1 - 1.2 9.0 10.3 12 5.7 5.9 2.5 2 1 0 2 2 2 0 Fatty acid desaturase Glyco_hydro_47 PF01532.20 KZN91294.1 - 2.6e-181 603.5 0.1 3e-181 603.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 KZN91294.1 - 0.042 12.4 0.1 5.1 5.5 0.0 2.1 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Med20 PF08612.11 KZN91295.1 - 2.6e-78 262.5 0.0 3e-78 262.3 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex EF-hand_1 PF00036.32 KZN91296.1 - 1.3e-41 137.0 11.6 7.8e-10 37.6 0.9 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KZN91296.1 - 3.6e-36 123.4 5.3 3.9e-19 68.9 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KZN91296.1 - 1.9e-34 117.3 11.5 2.4e-15 56.1 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KZN91296.1 - 3.8e-30 101.2 8.5 7.1e-09 34.9 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KZN91296.1 - 6.8e-26 88.6 9.8 4.7e-06 25.9 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KZN91296.1 - 1.4e-16 60.5 0.4 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KZN91296.1 - 6.8e-10 38.8 1.6 0.00078 19.4 0.3 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KZN91296.1 - 5.9e-09 36.2 0.2 0.0016 18.7 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 KZN91296.1 - 1e-06 28.6 0.1 0.008 16.2 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KZN91296.1 - 6.4e-06 26.2 1.6 2.3e-05 24.4 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 KZN91296.1 - 9.4e-05 23.2 0.2 0.0025 18.6 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 KZN91296.1 - 0.00013 21.9 0.3 0.35 10.8 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 KZN91296.1 - 0.00059 19.8 1.6 0.52 10.2 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 KZN91296.1 - 0.00062 20.1 0.7 0.66 10.3 0.1 2.6 2 1 1 3 3 3 2 RNA polymerase Rpb4 Dockerin_1 PF00404.18 KZN91296.1 - 0.0053 16.9 7.0 0.38 11.0 0.8 2.9 1 1 2 3 3 3 2 Dockerin type I domain DUF5580 PF17743.1 KZN91296.1 - 0.0057 15.3 0.0 0.0058 15.2 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 KZN91296.1 - 0.0084 16.0 0.7 0.32 10.9 0.1 2.2 1 1 1 2 2 2 1 SurA N-terminal domain EF-hand_14 PF17959.1 KZN91296.1 - 0.012 16.0 0.5 6.2 7.2 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain Poly_export PF02563.16 KZN91296.1 - 0.023 14.9 0.0 0.18 12.0 0.0 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein RuvA_C PF07499.13 KZN91296.1 - 0.058 13.9 0.1 8.5 6.9 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain dCache_2 PF08269.11 KZN91296.1 - 0.061 12.5 0.1 1 8.5 0.1 2.1 1 1 1 2 2 2 0 Cache domain MotA_activ PF09114.10 KZN91296.1 - 0.061 13.5 0.3 0.91 9.7 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain DUF4497 PF14924.6 KZN91296.1 - 0.092 13.2 0.0 8.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) RloB PF13707.6 KZN91296.1 - 0.11 12.7 1.3 0.72 10.0 0.2 2.1 1 1 1 2 2 2 0 RloB-like protein DUF5132 PF17195.4 KZN91296.1 - 0.16 12.1 0.5 21 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) SNARE PF05739.19 KZN91297.1 - 2.6e-13 49.7 0.4 5.9e-13 48.6 0.4 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KZN91297.1 - 3.6e-06 26.8 6.3 0.00026 20.7 0.8 2.2 2 0 0 2 2 2 2 Syntaxin HlyD_D4 PF16572.5 KZN91297.1 - 0.019 14.8 0.1 0.049 13.5 0.1 1.7 1 0 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB Syntaxin_2 PF14523.6 KZN91297.1 - 0.027 14.8 0.4 0.027 14.8 0.4 2.3 2 0 0 2 2 2 0 Syntaxin-like protein DUF3357 PF11837.8 KZN91297.1 - 0.15 12.6 0.0 0.37 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DNA_repr_REX1B PF14966.6 KZN91297.1 - 0.22 12.2 1.9 0.98 10.1 0.1 2.9 3 1 0 3 3 3 0 DNA repair REX1-B MCPsignal PF00015.21 KZN91297.1 - 0.29 10.9 7.3 0.13 12.0 1.3 2.7 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CTD_bind PF04818.13 KZN91298.1 - 1.6e-15 57.7 0.0 4.4e-15 56.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CREPT PF16566.5 KZN91298.1 - 0.0022 18.2 0.1 0.0045 17.2 0.1 1.7 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour Muted PF14942.6 KZN91298.1 - 0.12 12.7 1.0 0.23 11.8 1.0 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF3277 PF11681.8 KZN91298.1 - 0.13 12.1 0.2 0.64 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3277) Clathrin_lg_ch PF01086.17 KZN91299.1 - 1.7e-71 241.0 5.1 2e-71 240.7 5.1 1.1 1 0 0 1 1 1 1 Clathrin light chain CDC37_N PF03234.14 KZN91300.1 - 9.5e-50 168.8 2.2 9.5e-50 168.8 2.2 2.5 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 KZN91300.1 - 9.6e-42 141.6 0.4 3.1e-41 140.0 0.0 2.0 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KZN91300.1 - 1.9e-34 117.7 1.3 1e-33 115.4 1.4 2.3 2 0 0 2 2 2 1 Cdc37 C terminal domain DUF2385 PF09539.10 KZN91300.1 - 0.1 13.1 0.1 64 4.2 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2385) DUF4407 PF14362.6 KZN91300.1 - 0.3 10.4 4.1 1 8.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Spc29 PF17082.5 KZN91300.1 - 0.51 10.1 5.2 1.1 9.1 1.7 2.4 1 1 1 2 2 2 0 Spindle Pole Component 29 MutS_IV PF05190.18 KZN91300.1 - 2.3 8.6 5.0 5.6 7.4 0.3 3.0 3 0 0 3 3 3 0 MutS family domain IV ABC_membrane PF00664.23 KZN91301.1 - 1.2e-52 179.3 9.5 1.5e-52 179.0 9.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KZN91301.1 - 1.2e-36 126.3 0.0 3.3e-36 124.8 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KZN91301.1 - 3.2e-05 23.5 0.0 0.003 17.0 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KZN91301.1 - 0.0038 17.6 0.4 0.011 16.1 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KZN91301.1 - 0.0091 15.7 0.0 0.026 14.3 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KZN91301.1 - 0.022 14.5 0.1 0.068 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KZN91301.1 - 0.03 14.6 0.1 0.2 12.0 0.1 2.1 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KZN91301.1 - 0.033 13.9 0.1 0.43 10.3 0.0 2.5 2 1 1 3 3 3 0 IstB-like ATP binding protein AAA PF00004.29 KZN91301.1 - 0.034 14.6 0.0 0.22 12.0 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 KZN91301.1 - 0.072 11.9 0.1 0.27 10.0 0.1 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class SbcCD_C PF13558.6 KZN91301.1 - 0.075 13.3 1.2 1.4 9.2 0.7 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DEAD PF00270.29 KZN91301.1 - 0.12 12.2 0.0 1.5 8.6 0.0 2.4 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_23 PF13476.6 KZN91301.1 - 0.32 11.5 0.1 0.32 11.5 0.1 2.2 3 0 0 3 3 2 0 AAA domain Nucleoside_tran PF01733.18 KZN91302.1 - 1.9e-41 142.5 16.8 3.8e-39 134.9 16.8 2.9 1 1 0 1 1 1 1 Nucleoside transporter DUF2207 PF09972.9 KZN91302.1 - 0.036 12.8 1.8 3.1 6.4 0.0 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) CoA_binding_3 PF13727.6 KZN91302.1 - 1.3 9.0 12.0 2.7 8.0 0.5 3.8 4 0 0 4 4 4 0 CoA-binding domain p450 PF00067.22 KZN91303.1 - 2.9e-65 220.8 0.0 3.4e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Haspin_kinase PF12330.8 KZN91304.1 - 1e-39 136.5 0.0 1.6e-39 135.9 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain DUF1682 PF07946.14 KZN91306.1 - 1.8e-109 365.9 0.3 2.1e-109 365.6 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Polysacc_deac_1 PF01522.21 KZN91307.1 - 2.5e-28 98.5 0.0 4e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Creatininase PF02633.14 KZN91307.1 - 6.3e-07 29.1 0.3 1.2e-06 28.2 0.3 1.4 1 0 0 1 1 1 1 Creatinine amidohydrolase Glyco_hydro_57 PF03065.15 KZN91307.1 - 5.6e-05 22.5 0.0 0.00016 21.0 0.1 1.6 1 1 1 2 2 2 1 Glycosyl hydrolase family 57 Nitroreductase PF00881.24 KZN91308.1 - 2.4e-16 60.3 0.0 3.8e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family Pkinase PF00069.25 KZN91309.1 - 3e-14 53.0 0.0 1.1e-13 51.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN91309.1 - 1.4e-08 34.4 0.0 1.8e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KZN91309.1 - 0.0031 16.9 0.0 0.013 14.8 0.1 1.8 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KZN91309.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family MFS_1 PF07690.16 KZN91310.1 - 2.4e-22 79.4 80.1 1.6e-20 73.4 52.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Bac_export_2 PF01312.19 KZN91310.1 - 9.1 5.4 6.4 0.54 9.4 0.4 1.9 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family Glyoxalase PF00903.25 KZN91311.1 - 1.3e-08 35.1 0.1 7.2e-08 32.7 0.1 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KZN91311.1 - 0.00031 21.0 0.0 0.00038 20.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KZN91311.1 - 0.089 12.9 0.0 0.42 10.7 0.0 1.9 1 1 0 1 1 1 0 Glyoxalase-like domain LOR PF04525.12 KZN91312.1 - 1.7e-05 24.5 0.0 4.1e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 LURP-one-related adh_short PF00106.25 KZN91313.1 - 2.3e-07 30.5 0.0 2.8e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KZN91313.1 - 1.1e-05 25.0 0.0 1.4e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KZN91313.1 - 0.00067 19.9 0.0 0.0011 19.3 0.0 1.2 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_10 PF13460.6 KZN91313.1 - 0.002 18.0 0.0 0.0026 17.7 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding adh_short_C2 PF13561.6 KZN91313.1 - 0.015 14.8 0.0 0.02 14.5 0.0 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.17 KZN91313.1 - 0.027 13.6 0.0 0.032 13.3 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain KR PF08659.10 KZN91313.1 - 0.031 14.2 0.2 0.031 14.2 0.2 1.9 2 1 0 2 2 2 0 KR domain 3Beta_HSD PF01073.19 KZN91313.1 - 0.041 12.9 0.0 0.056 12.5 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KZN91313.1 - 0.058 12.5 0.0 0.066 12.3 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein UPF0146 PF03686.13 KZN91313.1 - 0.082 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Sacchrp_dh_NADP PF03435.18 KZN91313.1 - 0.088 13.1 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Gp_dh_N PF00044.24 KZN91313.1 - 0.1 12.9 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain adh_short PF00106.25 KZN91314.1 - 9.4e-18 64.4 0.1 1.6e-17 63.7 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN91314.1 - 1.2e-09 38.1 0.0 1.5e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF2464 PF10240.9 KZN91314.1 - 0.18 11.3 0.0 0.26 10.8 0.0 1.1 1 0 0 1 1 1 0 Multivesicular body subunit 12 NUDIX PF00293.28 KZN91315.1 - 5.5e-21 75.0 0.0 6.6e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KZN91315.1 - 0.0051 16.8 0.0 0.0079 16.2 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain Antimicrobial_9 PF08104.11 KZN91315.1 - 0.099 12.7 0.3 0.2 11.7 0.3 1.5 1 0 0 1 1 1 0 Ponericin L family RNase_H PF00075.24 KZN91318.1 - 3.9e-25 88.7 0.0 6.3e-25 88.0 0.0 1.4 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 KZN91318.1 - 0.0086 15.9 0.1 0.18 11.6 0.1 2.3 1 1 0 1 1 1 1 Reverse transcriptase-like Ins_P5_2-kin PF06090.12 KZN91319.1 - 3.9e-47 161.3 0.0 9.7e-47 160.0 0.0 1.6 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Thiamine_BP PF01910.17 KZN91320.1 - 4.6e-31 106.6 0.2 5.2e-31 106.4 0.2 1.0 1 0 0 1 1 1 1 Thiamine-binding protein PI-PLC-X PF00388.19 KZN91321.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain COX7a PF02238.15 KZN91322.1 - 9.4e-24 83.6 2.6 1.2e-23 83.3 2.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Epsilon_antitox PF08998.11 KZN91323.1 - 0.085 13.1 0.1 0.72 10.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial epsilon antitoxin Aminotran_5 PF00266.19 KZN91324.1 - 1.7e-09 37.1 0.0 1.8e-08 33.7 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KZN91324.1 - 0.042 13.2 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family IDO PF01231.18 KZN91325.1 - 4.2e-141 470.7 0.0 5e-141 470.4 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase YEATS PF03366.16 KZN91326.1 - 3.6e-36 123.0 2.2 5.4e-36 122.4 2.2 1.3 1 0 0 1 1 1 1 YEATS family M16C_assoc PF08367.11 KZN91326.1 - 0.24 10.5 1.6 0.35 10.0 1.6 1.2 1 0 0 1 1 1 0 Peptidase M16C associated NAD_binding_10 PF13460.6 KZN91327.1 - 4.6e-07 29.9 0.0 4.6e-06 26.6 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KZN91327.1 - 2.6e-05 23.8 0.0 7.2e-05 22.4 0.0 1.7 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KZN91327.1 - 0.00063 18.8 0.0 0.0033 16.5 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KZN91327.1 - 0.014 14.8 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 KZN91327.1 - 0.047 12.8 0.0 0.17 10.9 0.0 1.9 3 0 0 3 3 3 0 RmlD substrate binding domain SYF2 PF08231.12 KZN91328.1 - 1.5e-55 188.0 15.6 1.5e-55 188.0 15.6 2.1 2 0 0 2 2 2 1 SYF2 splicing factor Pneumo_att_G PF05539.11 KZN91328.1 - 1.3 8.5 7.2 1.7 8.1 7.2 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Velvet PF11754.8 KZN91330.1 - 4.9e-60 203.6 2.5 1.7e-59 201.8 0.0 2.2 2 0 0 2 2 2 1 Velvet factor PRP38_assoc PF12871.7 KZN91330.1 - 5 7.8 25.9 0.71 10.5 19.2 2.6 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term SSURE PF11966.8 KZN91331.1 - 0.07 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Fibronectin-binding repeat Ribosomal_L12 PF00542.19 KZN91332.1 - 1e-19 70.6 4.8 7.2e-19 67.9 3.7 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KZN91332.1 - 1.3e-12 47.2 7.3 1.3e-12 47.2 7.3 3.3 4 1 0 4 4 4 1 Ribosomal protein L7/L12 dimerisation domain SpoVIF PF14069.6 KZN91332.1 - 0.057 13.2 0.6 0.22 11.3 0.1 2.1 2 1 0 2 2 2 0 Stage VI sporulation protein F Cpn60_TCP1 PF00118.24 KZN91333.1 - 8e-138 460.1 5.5 9e-138 459.9 5.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PrpR_N PF06506.11 KZN91333.1 - 0.1 12.2 1.1 0.82 9.2 0.1 2.7 3 0 0 3 3 3 0 Propionate catabolism activator Peptidase_M48 PF01435.18 KZN91334.1 - 7.9e-20 71.5 0.0 1.1e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 DUF2268 PF10026.9 KZN91334.1 - 0.085 12.4 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) PH_10 PF15411.6 KZN91335.1 - 2.2e-26 92.5 0.1 3.9e-26 91.7 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 KZN91335.1 - 2.6e-13 50.6 0.0 4.8e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KZN91335.1 - 8.8e-13 48.5 0.0 1.6e-11 44.4 0.0 2.6 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 KZN91335.1 - 5.1e-07 30.3 0.0 1.2e-06 29.1 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 KZN91335.1 - 0.00032 21.0 7.5 0.0006 20.1 7.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KZN91335.1 - 0.012 15.5 7.5 0.021 14.8 7.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KZN91335.1 - 0.033 14.0 7.1 0.063 13.1 7.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KZN91335.1 - 0.038 13.6 8.6 0.021 14.4 5.4 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KZN91335.1 - 0.04 13.7 2.8 0.094 12.5 2.8 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 KZN91335.1 - 0.054 13.8 4.1 0.12 12.7 4.1 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain NlpE_C PF17185.4 KZN91335.1 - 0.14 12.4 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 NlpE C-terminal OB domain zf-C3HC4_3 PF13920.6 KZN91335.1 - 0.15 11.9 4.5 0.27 11.1 4.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KZN91335.1 - 0.15 11.9 6.8 0.29 11.0 6.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PH PF00169.29 KZN91335.1 - 0.16 12.5 0.1 0.43 11.1 0.0 1.8 2 0 0 2 2 1 0 PH domain preSET_CXC PF18264.1 KZN91335.1 - 0.74 10.3 3.0 1.5 9.4 3.0 1.5 1 0 0 1 1 1 0 CXC domain zf-RING-like PF08746.11 KZN91335.1 - 1.6 9.1 6.7 2.9 8.3 6.7 1.4 1 0 0 1 1 1 0 RING-like domain E1_dh PF00676.20 KZN91337.1 - 4.5e-114 380.4 0.4 5.4e-114 380.2 0.4 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KZN91337.1 - 0.0012 18.2 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase DUF16 PF01519.16 KZN91338.1 - 0.55 10.8 3.6 51 4.4 3.3 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 G-gamma PF00631.22 KZN91338.1 - 2.2 8.4 4.0 2.7 8.0 2.2 2.1 2 0 0 2 2 2 0 GGL domain S4 PF01479.25 KZN91339.1 - 8.9e-16 57.4 0.0 1.8e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 S4 domain Glyco_hydro_11 PF00457.17 KZN91339.1 - 0.048 13.3 0.8 0.087 12.5 0.8 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 11 S4_2 PF13275.6 KZN91339.1 - 0.17 11.7 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 S4 domain SPG4 PF17325.2 KZN91339.1 - 0.5 11.5 7.9 0.32 12.1 0.4 2.6 2 0 0 2 2 2 0 Stationary phase protein 4 Peptidase_S64 PF08192.11 KZN91339.1 - 2.9 6.3 8.8 3.8 5.9 8.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 CPSF100_C PF13299.6 KZN91339.1 - 3.9 7.6 10.1 0.1 12.8 2.1 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF3636 PF12331.8 KZN91340.1 - 3.6e-48 163.2 0.4 6.8e-48 162.3 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) LCD1 PF09798.9 KZN91340.1 - 0.00016 20.4 1.8 0.62 8.5 0.1 3.1 2 1 1 3 3 3 3 DNA damage checkpoint protein Mu-like_Pro PF10123.9 KZN91340.1 - 0.0017 18.0 1.8 0.0033 17.0 1.8 1.4 1 0 0 1 1 1 1 Mu-like prophage I protein UPF0449 PF15136.6 KZN91340.1 - 0.055 13.9 0.3 0.56 10.7 0.1 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Phage_Mu_Gam PF07352.12 KZN91340.1 - 0.078 12.9 0.8 0.15 11.9 0.8 1.5 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein CTP_transf_1 PF01148.20 KZN91341.1 - 2.5e-81 273.4 21.8 3.1e-81 273.1 21.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF389 PF04087.14 KZN91341.1 - 0.079 13.0 0.9 5.1 7.1 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF389) Cyclin_N PF00134.23 KZN91342.1 - 2.1e-10 40.4 0.0 2.4e-08 33.8 0.0 2.5 2 1 1 3 3 3 2 Cyclin, N-terminal domain MRP-S34 PF16053.5 KZN91342.1 - 0.053 13.2 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S34 GST_N_3 PF13417.6 KZN91343.1 - 2.9e-18 66.0 0.1 5.6e-18 65.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KZN91343.1 - 1.1e-16 60.9 0.1 4.4e-16 59.0 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KZN91343.1 - 3.9e-09 36.7 0.1 7.3e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KZN91343.1 - 1.4e-07 31.4 0.3 3.9e-07 30.0 0.3 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KZN91343.1 - 0.058 13.6 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Fructosamin_kin PF03881.14 KZN91344.1 - 8.4e-68 228.7 0.0 1.2e-67 228.2 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase Arm PF00514.23 KZN91344.1 - 3.9e-15 55.3 8.8 4.6e-05 23.3 0.0 7.8 11 0 0 11 11 11 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KZN91344.1 - 0.00059 20.3 0.1 1.2 9.7 0.0 5.3 5 0 0 5 5 5 1 HEAT-like repeat HEAT PF02985.22 KZN91344.1 - 0.015 15.5 3.9 36 5.0 0.1 6.1 6 1 1 7 7 7 0 HEAT repeat HEAT_2 PF13646.6 KZN91344.1 - 0.066 13.6 2.6 12 6.4 0.1 4.7 5 1 1 6 6 6 0 HEAT repeats Cyclin PF08613.11 KZN91345.1 - 1.2e-32 113.6 0.9 3.8e-32 111.9 0.9 1.9 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KZN91345.1 - 0.00017 21.3 0.0 0.00027 20.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DEC-1_N PF04625.13 KZN91345.1 - 0.0084 15.2 5.2 0.014 14.4 5.2 1.3 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region dCMP_cyt_deam_1 PF00383.23 KZN91346.1 - 3.4e-05 23.6 0.3 0.29 11.0 0.1 2.5 2 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Na_Ca_ex PF01699.24 KZN91347.1 - 2.1e-34 118.7 34.7 3.1e-18 66.2 18.4 2.0 2 0 0 2 2 2 2 Sodium/calcium exchanger protein UCH PF00443.29 KZN91348.1 - 9e-47 159.7 0.0 1.4e-46 159.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KZN91348.1 - 7.1e-11 42.3 0.0 1.8e-06 27.8 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Ndc1_Nup PF09531.10 KZN91348.1 - 0.89 8.2 5.8 2.2 6.9 5.7 1.6 1 1 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-C3HC4 PF00097.25 KZN91349.1 - 3.8e-07 29.9 7.7 6.4e-07 29.1 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KZN91349.1 - 3e-06 27.1 3.0 3e-06 27.1 3.0 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KZN91349.1 - 3.5e-06 26.7 4.8 2.8e-05 23.9 2.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KZN91349.1 - 1e-05 25.8 8.1 8.8e-05 22.8 8.5 2.1 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KZN91349.1 - 2.1e-05 24.6 4.9 0.00012 22.1 5.4 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KZN91349.1 - 2.6e-05 24.1 4.8 6e-05 22.9 4.7 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KZN91349.1 - 2.9e-05 23.8 6.7 6.3e-05 22.7 6.7 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KZN91349.1 - 0.064 13.1 9.0 0.53 10.2 9.2 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KZN91349.1 - 0.33 11.1 2.1 0.79 9.9 2.1 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 KZN91349.1 - 2 8.2 6.3 8 6.3 3.5 2.6 2 1 0 2 2 2 0 RING-like zinc finger zf-rbx1 PF12678.7 KZN91349.1 - 7.6 6.9 7.1 24 5.3 7.1 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain ERG4_ERG24 PF01222.17 KZN91350.1 - 1.4e-140 468.9 20.1 1.6e-140 468.7 20.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DLH PF01738.18 KZN91351.1 - 4.3e-28 98.4 0.0 5.3e-28 98.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 KZN91351.1 - 0.0054 16.7 0.1 0.2 11.6 0.1 2.1 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 KZN91351.1 - 0.065 12.8 0.0 0.14 11.7 0.0 1.5 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) LIDHydrolase PF10230.9 KZN91351.1 - 0.071 12.7 0.0 0.09 12.3 0.0 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase FSH1 PF03959.13 KZN91351.1 - 0.16 11.6 0.0 0.37 10.4 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Chs7 PF12271.8 KZN91352.1 - 1.7e-110 368.9 4.5 1.9e-110 368.7 4.5 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone TssN PF17555.2 KZN91352.1 - 2.8 7.3 13.6 2 7.7 4.4 2.4 1 1 0 2 2 2 0 Type VI secretion system, TssN DUF2070 PF09843.9 KZN91352.1 - 5.7 5.1 7.3 7.2 4.8 7.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) BC10 PF06726.12 KZN91353.1 - 2e-15 56.8 9.4 3.1e-15 56.1 9.4 1.3 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Ge1_WD40 PF16529.5 KZN91354.1 - 0.0011 18.0 0.0 0.0031 16.5 0.0 1.7 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein POR PF01558.18 KZN91354.1 - 0.079 13.0 0.2 0.24 11.4 0.2 1.8 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase DUF2203 PF09969.9 KZN91354.1 - 1.8 9.3 5.6 0.57 10.9 0.9 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Na_H_Exchanger PF00999.21 KZN91355.1 - 4.5e-47 160.7 21.0 5.7e-47 160.3 21.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Cauli_VI PF01693.16 KZN91356.1 - 4.8e-36 122.8 6.3 1.1e-17 64.0 1.4 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 KZN91356.1 - 5.7e-35 120.6 0.0 9.1e-35 119.9 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KZN91356.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like NMO PF03060.15 KZN91357.1 - 4.3e-34 118.4 7.2 2e-32 112.9 7.2 2.1 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 KZN91357.1 - 5.2e-09 35.6 1.5 8.3e-09 34.9 1.5 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KZN91357.1 - 1.5e-08 34.0 3.3 3.7e-08 32.8 0.3 2.6 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KZN91357.1 - 0.0043 16.3 0.5 0.0072 15.5 0.5 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Ribul_P_3_epim PF00834.19 KZN91357.1 - 0.051 13.0 0.6 1.1 8.6 0.1 2.2 1 1 1 2 2 2 0 Ribulose-phosphate 3 epimerase family FMN_dh PF01070.18 KZN91358.1 - 2.6e-109 365.4 0.0 3.1e-109 365.2 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KZN91358.1 - 5.5e-20 71.3 0.0 1.2e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 KZN91358.1 - 3.4e-05 23.0 0.5 0.00054 19.1 0.1 2.6 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KZN91358.1 - 4.2e-05 22.8 0.0 7.5e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KZN91358.1 - 0.021 14.3 0.0 0.24 10.8 0.0 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein DUF202 PF02656.15 KZN91359.1 - 0.0028 18.1 8.8 0.028 14.8 8.8 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF202) 6PF2K PF01591.18 KZN91360.1 - 4.8e-71 238.6 0.0 1.2e-50 171.9 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KZN91360.1 - 7.5e-33 113.9 0.1 6.8e-25 87.9 0.0 2.5 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KZN91360.1 - 1.1e-05 25.6 0.0 0.21 11.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain KTI12 PF08433.10 KZN91360.1 - 0.073 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF5128 PF17170.4 KZN91360.1 - 0.13 11.3 0.1 0.22 10.6 0.1 1.2 1 0 0 1 1 1 0 6-bladed beta-propeller DSBA PF01323.20 KZN91361.1 - 2.2e-32 112.4 0.1 4.1e-31 108.3 0.1 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 KZN91361.1 - 0.096 12.7 0.1 1.5 8.9 0.1 2.3 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_5 PF13743.6 KZN91361.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin VTC PF09359.10 KZN91362.1 - 2.3e-86 289.6 1.3 2.5e-86 289.5 0.1 1.6 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 KZN91362.1 - 2.9e-13 50.0 2.7 2.9e-13 50.0 2.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 KZN91362.1 - 6.2e-11 42.8 13.7 7.9e-05 22.7 0.2 4.3 2 1 1 4 4 4 4 SPX domain NUDIX PF00293.28 KZN91363.1 - 1.7e-11 44.3 0.0 3.1e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain CBFD_NFYB_HMF PF00808.23 KZN91364.1 - 6e-05 23.2 0.1 8.2e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.6 KZN91364.1 - 0.00011 22.4 0.1 0.00011 22.3 0.1 1.1 1 0 0 1 1 1 1 CENP-W protein COQ7 PF03232.13 KZN91365.1 - 0.074 12.8 2.9 0.14 12.0 2.9 1.4 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 HrcA_DNA-bdg PF03444.15 KZN91365.1 - 0.13 12.0 0.2 18 5.1 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Mod_r PF07200.13 KZN91365.1 - 1.3 9.1 9.9 2.6 8.1 9.9 1.5 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF4709 PF15821.5 KZN91365.1 - 1.4 9.2 6.4 1.1 9.5 2.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4709) MFS_1 PF07690.16 KZN91366.1 - 5.1e-45 153.9 14.0 5.1e-45 153.9 14.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN91366.1 - 6.9e-06 25.2 5.2 1.5e-05 24.1 5.2 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KZN91366.1 - 0.00014 20.4 1.0 0.00022 19.8 1.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 KZN91366.1 - 0.00026 20.1 0.9 0.00026 20.1 0.9 1.6 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 KZN91366.1 - 0.11 11.3 9.5 0.096 11.5 4.5 2.6 2 1 0 2 2 2 0 MFS_1 like family MMU163 PF17119.5 KZN91367.1 - 1.3e-115 384.8 0.2 1.8e-115 384.3 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial protein up-regulated during meiosis Mcl1_mid PF12341.8 KZN91368.1 - 1.2e-102 343.3 0.0 1.4e-101 339.8 0.0 2.2 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 KZN91368.1 - 1.4e-16 60.6 3.7 7.5e-06 26.6 0.1 7.0 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN91368.1 - 2.2e-15 56.7 0.0 1.4e-05 25.2 0.0 7.1 3 1 4 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KZN91368.1 - 1.5e-07 30.9 0.0 2.9e-06 26.6 0.0 2.2 1 1 1 2 2 2 1 Coatomer WD associated region DNA_pol_alpha_N PF12254.8 KZN91368.1 - 0.011 15.8 2.6 0.026 14.6 2.6 1.6 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal Cytochrom_D1 PF02239.16 KZN91368.1 - 0.013 14.1 0.3 0.37 9.3 0.1 2.4 1 1 1 2 2 2 0 Cytochrome D1 heme domain Collagen_bind_2 PF12904.7 KZN91368.1 - 0.059 13.4 0.1 0.2 11.7 0.1 1.9 1 0 0 1 1 1 0 Putative collagen-binding domain of a collagenase PD40 PF07676.12 KZN91368.1 - 0.061 13.3 0.2 40 4.3 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Herpes_UL56 PF04534.12 KZN91368.1 - 0.12 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL56 protein ILVD_EDD PF00920.21 KZN91369.1 - 1.2e-164 548.8 0.4 1.3e-164 548.6 0.4 1.0 1 0 0 1 1 1 1 Dehydratase family p450 PF00067.22 KZN91370.1 - 4.7e-13 48.7 0.0 8.9e-13 47.8 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 LicD PF04991.13 KZN91370.1 - 0.098 12.8 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 LicD family RNA12 PF10443.9 KZN91371.1 - 1.4e-166 554.7 0.0 5.6e-166 552.7 0.0 1.9 1 1 0 1 1 1 1 RNA12 protein ATPase_2 PF01637.18 KZN91371.1 - 3.1e-06 27.3 0.0 5.9e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea RRM_1 PF00076.22 KZN91371.1 - 1.2e-05 25.0 0.0 3.8e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.6 KZN91371.1 - 0.0019 18.6 0.0 0.0042 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF2487 PF10673.9 KZN91371.1 - 0.0022 18.0 0.0 0.0056 16.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) DUF3128 PF11326.8 KZN91372.1 - 6.1e-25 87.4 2.1 6.1e-25 87.4 2.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3128) RhlB PF12300.8 KZN91373.1 - 0.0066 16.6 10.3 0.0076 16.4 9.9 1.4 1 1 0 1 1 1 1 ATP-dependent RNA helicase RhlB Corona_nucleoca PF00937.18 KZN91373.1 - 0.11 11.5 3.0 0.14 11.1 2.9 1.2 1 1 0 1 1 1 0 Coronavirus nucleocapsid protein Sugarporin_N PF11471.8 KZN91373.1 - 0.13 12.2 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension GATase_2 PF00310.21 KZN91374.1 - 4.4e-180 598.9 0.0 6e-180 598.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KZN91374.1 - 1.1e-154 515.0 0.0 1.6e-154 514.5 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KZN91374.1 - 3.2e-113 377.9 0.0 2.2e-111 371.8 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 KZN91374.1 - 5e-86 287.2 2.6 8.1e-86 286.5 2.6 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 KZN91374.1 - 5.3e-26 91.5 0.1 3.7e-25 88.8 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KZN91374.1 - 9e-21 73.8 0.0 1.8e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 KZN91374.1 - 1.6e-08 34.6 0.1 6.6e-08 32.7 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KZN91374.1 - 8.4e-08 32.7 0.1 0.00043 20.8 0.1 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KZN91374.1 - 2.7e-06 27.0 0.1 4.8e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KZN91374.1 - 6.3e-06 26.0 1.2 0.0055 16.3 0.3 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KZN91374.1 - 7.5e-06 25.4 2.2 0.038 13.2 0.0 3.8 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KZN91374.1 - 1.2e-05 24.6 0.1 0.00026 20.2 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KZN91374.1 - 3.2e-05 23.5 0.6 6.6e-05 22.4 0.6 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KZN91374.1 - 5.8e-05 22.0 0.3 0.00015 20.6 0.3 1.7 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KZN91374.1 - 0.00058 19.2 0.1 0.0011 18.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KZN91374.1 - 0.0023 17.2 0.1 0.58 9.4 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KZN91374.1 - 0.014 15.8 1.2 9.2 6.8 0.1 2.9 2 0 0 2 2 2 0 Putative NAD(P)-binding Thi4 PF01946.17 KZN91374.1 - 0.017 14.4 0.6 0.052 12.8 0.2 2.0 2 0 0 2 2 2 0 Thi4 family FMN_dh PF01070.18 KZN91374.1 - 0.024 13.7 1.2 0.083 11.9 0.9 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase FMO-like PF00743.19 KZN91374.1 - 0.088 11.2 0.1 4 5.7 0.0 2.7 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like Lycopene_cycl PF05834.12 KZN91374.1 - 0.11 11.6 0.3 0.45 9.5 0.2 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein MADF_DNA_bdg PF10545.9 KZN91374.1 - 0.17 12.2 0.4 0.4 11.0 0.4 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like GIDA PF01134.22 KZN91374.1 - 0.85 8.6 5.7 0.09 11.8 0.5 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Apc15p PF05841.11 KZN91375.1 - 6e-16 59.4 1.4 7.8e-16 59.0 0.2 1.8 2 0 0 2 2 2 1 Apc15p protein OPT PF03169.15 KZN91377.1 - 4.5e-136 455.0 46.2 5.1e-136 454.8 46.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.6 KZN91377.1 - 0.17 11.2 1.0 0.44 9.9 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) SieB PF14163.6 KZN91377.1 - 0.28 10.7 4.9 1 8.8 4.9 2.0 1 1 0 1 1 1 0 Super-infection exclusion protein B DUF2721 PF11026.8 KZN91377.1 - 0.89 9.5 10.3 0.72 9.7 0.2 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) HSP70 PF00012.20 KZN91378.1 - 1.2e-261 869.2 7.2 1.3e-261 869.0 7.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KZN91378.1 - 9e-18 64.2 0.1 4.2e-17 62.0 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KZN91378.1 - 0.0013 18.5 0.0 0.0035 17.1 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KZN91378.1 - 0.0035 17.7 4.3 4.7 7.7 0.0 3.6 3 2 0 3 3 3 2 Cell division protein FtsA BcrAD_BadFG PF01869.20 KZN91378.1 - 0.0086 15.6 0.0 0.73 9.3 0.0 2.4 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.18 KZN91378.1 - 0.02 14.2 0.2 0.041 13.2 0.2 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase PMBR PF09373.10 KZN91378.1 - 0.044 14.0 0.1 0.41 10.9 0.1 2.6 2 0 0 2 2 2 0 Pseudomurein-binding repeat StbA PF06406.11 KZN91378.1 - 0.044 13.0 0.0 0.085 12.1 0.0 1.4 1 0 0 1 1 1 0 StbA protein NCE101 PF11654.8 KZN91379.1 - 2.4e-09 36.7 0.1 5.5e-09 35.6 0.0 1.6 2 0 0 2 2 2 1 Non-classical export protein 1 DUF2012 PF09430.10 KZN91380.1 - 1.3e-29 102.9 0.0 1.6e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) WW PF00397.26 KZN91381.1 - 2.5e-11 43.5 3.6 2.5e-11 43.5 3.6 2.2 2 0 0 2 2 2 1 WW domain DUF2076 PF09849.9 KZN91381.1 - 1.6e-07 31.7 14.4 1.6e-07 31.7 14.4 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) WD40 PF00400.32 KZN91382.1 - 0.0041 17.9 16.5 1.3 10.0 0.0 6.7 7 0 0 7 7 7 2 WD domain, G-beta repeat RR_TM4-6 PF06459.12 KZN91382.1 - 0.97 9.2 7.5 2 8.2 7.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mito_carr PF00153.27 KZN91383.1 - 1.2e-52 175.8 2.2 3.9e-17 61.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein AphA_like PF14557.6 KZN91383.1 - 0.0055 16.5 0.0 0.013 15.2 0.0 1.6 2 0 0 2 2 2 1 Putative AphA-like transcriptional regulator Bacteriocin_IIc PF10439.9 KZN91383.1 - 0.023 14.8 2.3 0.53 10.5 0.2 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide PrcB_C PF14343.6 KZN91383.1 - 0.093 12.9 0.0 2.2 8.5 0.0 2.3 2 0 0 2 2 2 0 PrcB C-terminal Ras PF00071.22 KZN91384.1 - 9.7e-66 220.3 0.5 1.1e-65 220.1 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KZN91384.1 - 6.7e-36 123.1 0.1 1.2e-35 122.3 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KZN91384.1 - 2.5e-16 59.6 0.1 2.9e-16 59.4 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KZN91384.1 - 2.3e-05 24.4 0.0 8.7e-05 22.6 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KZN91384.1 - 2.7e-05 24.1 0.3 0.13 12.2 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KZN91384.1 - 0.00012 21.7 0.4 0.00031 20.3 0.2 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KZN91384.1 - 0.00025 20.5 0.1 0.00032 20.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA PF00004.29 KZN91384.1 - 0.00053 20.4 0.1 0.2 12.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 KZN91384.1 - 0.00086 18.8 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KZN91384.1 - 0.0057 16.2 0.0 0.035 13.6 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 KZN91384.1 - 0.0089 16.4 0.0 0.013 15.9 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KZN91384.1 - 0.029 14.6 0.0 0.067 13.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 KZN91384.1 - 0.036 13.3 0.1 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 Septin AAA_29 PF13555.6 KZN91384.1 - 0.057 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 KZN91384.1 - 0.067 12.6 0.0 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.14 KZN91384.1 - 0.067 13.2 0.0 0.12 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 KZN91384.1 - 0.068 13.7 0.1 0.15 12.5 0.1 1.8 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 KZN91384.1 - 0.077 12.6 0.1 2.2 7.8 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KZN91384.1 - 0.09 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 KZN91384.1 - 0.094 12.5 0.1 1.2 8.9 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ERAP1_C PF11838.8 KZN91385.1 - 4e-87 292.7 0.1 6.5e-87 292.0 0.1 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KZN91385.1 - 5.6e-75 251.7 2.1 1e-73 247.5 2.1 2.2 1 1 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KZN91385.1 - 6.6e-43 147.1 0.2 1.1e-41 143.0 0.0 2.5 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Ssl1 PF04056.14 KZN91386.1 - 4.6e-75 251.7 0.0 6.1e-75 251.3 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 KZN91386.1 - 6.8e-19 67.9 9.5 6.8e-19 67.9 9.5 2.5 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 KZN91386.1 - 7.6e-16 58.7 0.0 1.6e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KZN91386.1 - 1.3e-05 25.6 0.0 1.9e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.14 KZN91386.1 - 0.2 11.1 4.4 0.35 10.3 4.4 1.4 1 0 0 1 1 1 0 Transcription factor Tfb4 DZR PF12773.7 KZN91386.1 - 7.7 6.6 24.3 1.7 8.7 5.8 3.2 2 1 0 2 2 2 0 Double zinc ribbon DUF5572 PF17733.1 KZN91387.1 - 2e-23 81.9 0.2 3.6e-23 81.2 0.2 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5572) PUF PF00806.19 KZN91388.1 - 3.1e-34 114.7 2.1 2.6e-05 23.7 0.0 8.8 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat CNOT1_HEAT_N PF16419.5 KZN91388.1 - 0.093 12.4 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 HEAT repeat TPT PF03151.16 KZN91389.1 - 1.1e-60 205.5 11.6 1.3e-60 205.2 11.6 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KZN91389.1 - 1.7e-08 34.7 29.3 8.5e-05 22.7 10.3 2.8 2 1 0 2 2 2 2 EamA-like transporter family PSII PF00421.19 KZN91389.1 - 0.019 13.7 0.0 0.031 13.0 0.0 1.3 1 0 0 1 1 1 0 Photosystem II protein Molybdopterin PF00384.22 KZN91390.1 - 3.2e-69 234.0 0.0 1.4e-66 225.2 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH_dhqG_C PF09326.11 KZN91390.1 - 1.5e-17 64.0 0.1 3.7e-17 62.7 0.1 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 KZN91390.1 - 1.8e-17 62.6 0.2 1.8e-17 62.6 0.2 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.6 KZN91390.1 - 3.6e-15 55.8 0.2 8.6e-15 54.6 0.2 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 KZN91390.1 - 0.12 12.2 1.1 3.4 7.6 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 KZN91390.1 - 0.4 10.8 2.4 0.51 10.5 1.0 1.9 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.11 KZN91390.1 - 0.45 10.6 2.3 9.8 6.3 2.3 2.6 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster XRCC4 PF06632.12 KZN91391.1 - 1.7e-10 40.3 1.9 2.2e-10 39.9 1.9 1.2 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 Integrase_H2C2 PF17921.1 KZN91393.1 - 1.2e-07 31.7 0.8 1.2e-07 31.7 0.8 2.2 3 0 0 3 3 3 1 Integrase zinc binding domain ER_lumen_recept PF00810.18 KZN91394.1 - 3.2e-54 183.8 7.8 3.2e-54 183.8 7.8 1.6 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KZN91394.1 - 0.0046 16.7 16.5 0.39 10.5 0.3 4.1 3 1 2 5 5 5 3 PQ loop repeat DUF382 PF04037.13 KZN91396.1 - 7.5e-60 200.7 1.1 1.7e-59 199.5 1.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.16 KZN91396.1 - 4.5e-20 71.3 2.0 1.1e-19 70.0 2.0 1.7 1 0 0 1 1 1 1 PSP Ribonuclease_3 PF00636.26 KZN91397.1 - 7.7e-15 55.4 0.0 1.6e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KZN91397.1 - 9.4e-12 45.2 0.0 2e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like tRNA-synt_2c PF01411.19 KZN91399.1 - 0.01 14.4 0.0 0.014 13.9 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (A) DUF3006 PF11213.8 KZN91400.1 - 0.21 11.8 0.0 0.57 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) Bromodomain PF00439.25 KZN91401.1 - 6.8e-15 54.9 0.0 1.2e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Trypan_PARP PF05887.11 KZN91401.1 - 0.11 12.4 3.5 0.19 11.7 3.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CKS PF01111.19 KZN91402.1 - 9e-35 118.8 0.7 9e-35 118.8 0.7 1.4 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit DUF3844 PF12955.7 KZN91404.1 - 1.2e-34 118.5 4.9 2.2e-34 117.7 4.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) GARS_A PF01071.19 KZN91404.1 - 0.16 11.8 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain zf-RING_2 PF13639.6 KZN91405.1 - 4.2e-12 46.2 6.5 6.6e-12 45.6 6.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KZN91405.1 - 7.4e-09 35.3 5.6 1.2e-08 34.6 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KZN91405.1 - 1.3e-08 34.4 1.9 2.4e-08 33.6 1.9 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KZN91405.1 - 1.4e-07 31.3 3.9 2.2e-07 30.6 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KZN91405.1 - 3.2e-06 27.0 3.6 5.1e-06 26.4 3.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KZN91405.1 - 5.9e-06 26.5 9.8 2.5e-05 24.4 9.8 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KZN91405.1 - 0.00037 20.5 0.8 0.00037 20.5 0.8 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KZN91405.1 - 0.002 18.0 2.8 0.0034 17.2 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KZN91405.1 - 0.0022 18.0 3.0 0.0059 16.6 3.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KZN91405.1 - 0.0091 15.6 3.3 0.016 14.8 3.3 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KZN91405.1 - 0.074 12.9 6.6 0.13 12.1 6.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KZN91405.1 - 0.15 12.0 5.6 0.42 10.5 5.6 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KZN91405.1 - 0.15 12.2 4.8 0.32 11.2 4.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.29 KZN91405.1 - 0.16 11.9 5.7 0.34 10.9 5.7 1.6 1 0 0 1 1 1 0 PHD-finger zf-C3H2C3 PF17122.5 KZN91405.1 - 0.43 10.6 3.3 1.1 9.4 3.3 1.7 1 0 0 1 1 1 0 Zinc-finger RINGv PF12906.7 KZN91405.1 - 0.59 10.3 4.0 1.3 9.2 4.0 1.6 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KZN91405.1 - 0.81 9.9 3.5 2.1 8.6 3.5 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.6 KZN91405.1 - 4.1 7.4 8.8 0.21 11.5 1.2 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Pro_isomerase PF00160.21 KZN91406.1 - 4.1e-48 163.6 0.8 4.5e-48 163.5 0.8 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD tRNA-synt_2c PF01411.19 KZN91407.1 - 1.7e-217 723.4 0.0 2.8e-217 722.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KZN91407.1 - 3.6e-17 62.2 0.5 7.7e-17 61.1 0.5 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KZN91407.1 - 6.1e-10 39.7 1.4 6.1e-10 39.7 1.4 2.2 2 0 0 2 2 2 1 DHHA1 domain HSP70 PF00012.20 KZN91408.1 - 5.7e-222 738.1 7.1 6.4e-222 738.0 7.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KZN91408.1 - 2.3e-16 59.6 0.6 8e-16 57.8 0.1 1.8 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KZN91408.1 - 0.00048 19.9 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain NAF PF03822.14 KZN91408.1 - 0.27 11.4 1.1 2.4 8.4 0.1 2.5 2 0 0 2 2 2 0 NAF domain RRF PF01765.19 KZN91409.1 - 2.9e-45 154.1 1.2 4e-45 153.7 1.2 1.2 1 0 0 1 1 1 1 Ribosome recycling factor SpoIIIAH PF12685.7 KZN91409.1 - 0.014 15.3 0.7 0.025 14.4 0.7 1.3 1 1 0 1 1 1 0 SpoIIIAH-like protein PcfJ PF14284.6 KZN91409.1 - 0.027 14.4 1.0 0.055 13.3 1.0 1.5 1 0 0 1 1 1 0 PcfJ-like protein DUF3813 PF12758.7 KZN91409.1 - 5.1 7.5 7.1 7 7.1 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3813) Zn_clus PF00172.18 KZN91411.1 - 3.5e-06 27.0 8.5 6.3e-06 26.2 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN91411.1 - 2e-05 23.8 0.0 3.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain FeS_assembly_P PF01883.19 KZN91412.1 - 1.8e-08 34.4 0.0 4.9e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein GTP_EFTU PF00009.27 KZN91413.1 - 2.2e-47 161.1 0.0 3.4e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KZN91413.1 - 6.9e-38 130.0 11.9 1.2e-37 129.2 11.9 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KZN91413.1 - 4.8e-24 84.5 0.0 1.2e-23 83.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KZN91413.1 - 1.1e-20 73.4 0.0 2.7e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KZN91413.1 - 1e-11 45.0 0.0 2.4e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KZN91413.1 - 1.6e-07 31.3 0.2 1.4e-06 28.3 0.0 2.3 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KZN91413.1 - 2.4e-06 27.6 0.1 4.4e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KZN91413.1 - 0.0091 15.6 0.0 0.033 13.8 0.0 1.9 1 1 0 1 1 1 1 Ras family Dynamin_N PF00350.23 KZN91413.1 - 0.17 11.9 0.1 22 5.0 0.1 2.5 1 1 1 2 2 2 0 Dynamin family Thiolase_N PF00108.23 KZN91414.1 - 1.7e-91 306.2 0.9 2.7e-91 305.5 0.9 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KZN91414.1 - 1.7e-43 147.2 2.8 1.9e-43 147.0 1.3 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KZN91414.1 - 2.5e-05 24.0 1.4 2.5e-05 24.0 1.4 2.5 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KZN91414.1 - 0.14 12.0 3.5 0.24 11.3 0.1 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Zip PF02535.22 KZN91415.1 - 6.2e-50 170.3 0.5 9.9e-50 169.6 0.5 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter LMBR1 PF04791.16 KZN91417.1 - 1.3e-21 77.1 5.6 1.3e-21 77.1 5.6 2.2 1 1 1 2 2 2 2 LMBR1-like membrane protein Anemone_cytotox PF06369.12 KZN91417.1 - 0.068 12.8 0.1 0.16 11.6 0.1 1.6 1 1 0 1 1 1 0 Sea anemone cytotoxic protein TMIE PF16038.5 KZN91417.1 - 0.095 12.6 0.0 0.61 10.0 0.0 2.3 2 0 0 2 2 2 0 TMIE protein DUF5134 PF17197.4 KZN91417.1 - 1.6 8.6 4.8 0.54 10.1 0.1 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF5134) CPSF_A PF03178.15 KZN91418.1 - 1.3e-106 356.6 0.0 2.8e-106 355.5 0.0 1.6 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 KZN91418.1 - 7.8e-18 64.4 0.0 1.5e-16 60.1 0.0 2.3 3 0 0 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term NDT80_PhoG PF05224.12 KZN91419.1 - 1.2e-41 143.0 0.2 3.3e-41 141.6 0.0 1.8 2 1 1 3 3 3 1 NDT80 / PhoG like DNA-binding family Glyco_hydro_3 PF00933.21 KZN91420.1 - 6.5e-69 232.7 0.0 8.7e-69 232.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 KZN91420.1 - 0.0033 17.7 0.0 0.011 16.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.22 KZN91420.1 - 0.015 15.3 0.0 0.03 14.2 0.0 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_6 PF13480.7 KZN91420.1 - 0.033 14.3 0.0 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Glucosamine_iso PF01182.20 KZN91421.1 - 2.7e-12 47.0 0.0 4.9e-12 46.2 0.0 1.3 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Aldedh PF00171.22 KZN91422.1 - 2.2e-155 517.7 0.5 2.7e-155 517.4 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GMC_oxred_N PF00732.19 KZN91423.1 - 1.1e-52 179.3 0.0 1.4e-52 179.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KZN91423.1 - 3.9e-37 128.0 0.0 5.9e-37 127.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KZN91423.1 - 6.3e-06 25.5 0.1 0.094 11.8 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KZN91423.1 - 0.00033 19.8 0.0 0.00051 19.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KZN91423.1 - 0.0018 18.5 0.1 0.006 16.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KZN91423.1 - 0.019 14.4 0.2 0.29 10.5 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase DAO PF01266.24 KZN91423.1 - 0.019 14.6 0.7 0.25 10.9 0.2 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KZN91423.1 - 0.024 15.2 0.5 4.2 8.0 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KZN91423.1 - 0.038 13.2 0.0 0.15 11.2 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KZN91423.1 - 0.2 10.9 0.1 3.4 6.9 0.0 2.5 3 0 0 3 3 3 0 Thi4 family Amidohydro_1 PF01979.20 KZN91424.1 - 6.5e-15 55.3 0.0 9e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KZN91424.1 - 2.1e-11 44.0 2.3 4.9e-08 32.9 0.0 3.1 3 0 0 3 3 3 3 Amidohydrolase family MFS_1 PF07690.16 KZN91425.1 - 4.6e-17 62.0 30.2 6.8e-17 61.4 30.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KZN91425.1 - 1.3e-10 41.2 5.0 1.3e-10 41.2 5.0 2.6 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 KZN91425.1 - 0.0011 17.9 6.3 0.0011 17.9 6.3 2.3 1 1 1 2 2 2 1 MFS_1 like family Peptidase_S10 PF00450.22 KZN91426.1 - 3.1e-107 359.6 0.3 3.6e-107 359.4 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase PEP-utilisers_N PF05524.13 KZN91427.1 - 0.097 12.9 0.9 1.6 8.9 0.2 2.7 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF1400 PF07176.11 KZN91427.1 - 0.12 12.7 0.1 0.78 10.0 0.1 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) RCR PF12273.8 KZN91428.1 - 1.9e-21 76.9 15.1 2.4e-21 76.6 15.1 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red SARAF PF06682.12 KZN91428.1 - 0.38 10.3 3.7 0.42 10.2 3.2 1.4 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SLD5_C PF16922.5 KZN91429.1 - 3.9e-15 55.8 1.2 6.7e-15 55.0 1.2 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KZN91429.1 - 2.4e-09 37.6 0.3 3.4e-09 37.1 0.3 1.3 1 0 0 1 1 1 1 GINS complex protein Cullin PF00888.22 KZN91430.1 - 1e-199 665.2 11.0 1e-199 665.2 11.0 1.5 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 KZN91430.1 - 8.3e-26 89.8 1.0 8.3e-26 89.8 1.0 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain zf-DNL PF05180.12 KZN91431.1 - 4e-28 97.1 0.4 6e-28 96.6 0.4 1.3 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.13 KZN91431.1 - 0.0035 17.0 0.5 0.0062 16.2 0.5 1.4 1 0 0 1 1 1 1 CSL zinc finger Elf1 PF05129.13 KZN91431.1 - 0.007 16.4 0.3 0.013 15.5 0.3 1.4 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like TFIIS_C PF01096.18 KZN91431.1 - 0.0074 16.1 2.6 0.55 10.1 0.4 2.4 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) TIP41 PF04176.13 KZN91431.1 - 0.028 13.9 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 TIP41-like family Zn-ribbon_8 PF09723.10 KZN91431.1 - 0.037 14.2 0.7 0.075 13.2 0.7 1.5 1 0 0 1 1 1 0 Zinc ribbon domain HypA PF01155.19 KZN91431.1 - 0.041 13.9 0.7 0.066 13.2 0.7 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA E7 PF00527.18 KZN91431.1 - 0.27 11.5 5.2 0.23 11.7 1.8 2.2 1 1 1 2 2 2 0 E7 protein, Early protein DNA_RNApol_7kD PF03604.13 KZN91431.1 - 0.36 10.6 1.6 4.8 7.0 0.4 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Zn_Tnp_IS1595 PF12760.7 KZN91431.1 - 2.4 8.2 6.9 25 5.0 0.5 2.4 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Pheromone PF08015.11 KZN91431.1 - 8.2 7.5 6.3 5.3 8.2 3.1 2.1 1 1 1 2 2 2 0 Fungal mating-type pheromone DRIM PF07539.12 KZN91432.1 - 2.7e-192 640.4 0.3 2.7e-192 640.4 0.3 4.5 6 0 0 6 6 6 1 Down-regulated in metastasis Arm_2 PF04826.13 KZN91432.1 - 0.011 15.2 0.2 0.35 10.3 0.0 3.0 3 0 0 3 3 3 0 Armadillo-like HEAT PF02985.22 KZN91432.1 - 0.035 14.3 7.7 0.11 12.8 0.0 6.0 7 0 0 7 7 7 0 HEAT repeat Katanin_con80 PF13925.6 KZN91432.1 - 0.068 13.2 0.7 1.1 9.2 0.1 3.0 3 0 0 3 3 3 0 con80 domain of Katanin BP28CT PF08146.12 KZN91432.1 - 0.096 12.5 0.0 0.65 9.8 0.0 2.5 1 0 0 1 1 1 0 BP28CT (NUC211) domain MMS19_C PF12460.8 KZN91432.1 - 0.15 11.1 10.5 5 6.1 0.0 5.1 5 0 0 5 5 5 0 RNAPII transcription regulator C-terminal CwfJ_C_1 PF04677.15 KZN91433.1 - 7.8e-24 83.9 0.0 2.4e-23 82.3 0.0 1.8 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KZN91433.1 - 8.5e-16 58.7 0.4 1.6e-15 57.8 0.4 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Rhodanese PF00581.20 KZN91435.1 - 1.3e-11 44.9 0.0 2.6e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain DNA_pol_phi PF04931.13 KZN91436.1 - 1.4e-262 873.3 19.6 1.7e-262 873.0 19.6 1.1 1 0 0 1 1 1 1 DNA polymerase phi SDA1 PF05285.12 KZN91436.1 - 0.00065 19.2 19.5 0.0016 17.9 19.5 1.6 1 0 0 1 1 1 1 SDA1 DUF1840 PF08895.11 KZN91436.1 - 0.24 11.8 8.8 1.4 9.3 1.9 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) MOSC PF03473.17 KZN91437.1 - 8.2e-29 100.3 0.0 1.3e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KZN91437.1 - 6.4e-22 77.7 0.0 3.2e-21 75.4 0.0 2.0 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain Peptidase_C15 PF01470.17 KZN91438.1 - 1e-11 45.4 0.0 0.00011 22.5 0.0 2.8 2 1 0 2 2 2 2 Pyroglutamyl peptidase p450 PF00067.22 KZN91439.1 - 3.5e-39 134.8 0.0 4.4e-39 134.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 QCR10 PF09796.9 KZN91439.1 - 0.044 13.9 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Mad3_BUB1_I PF08311.12 KZN91441.1 - 2.1e-44 150.5 0.0 5.2e-44 149.2 0.0 1.7 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 KZN91441.1 - 4.3e-11 42.8 0.0 3.7e-10 39.8 0.0 2.6 3 0 0 3 3 3 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 KZN91441.1 - 2.1e-08 33.9 0.0 1.7e-07 30.9 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN91441.1 - 0.0014 18.0 0.0 0.0044 16.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 KZN91441.1 - 0.012 15.7 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein Kinase-like PF14531.6 KZN91441.1 - 0.098 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like AP_endonuc_2 PF01261.24 KZN91442.1 - 2.8e-28 98.8 0.0 4.1e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel HHV6-IE PF03753.13 KZN91442.1 - 5.4 4.3 7.5 7.5 3.9 7.5 1.1 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein Rtf2 PF04641.12 KZN91442.1 - 8.9 5.6 14.8 2.8 7.2 3.4 2.5 2 0 0 2 2 2 0 Rtf2 RING-finger TPT PF03151.16 KZN91443.1 - 5.6e-23 81.7 16.2 7.2e-23 81.4 16.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KZN91443.1 - 0.00029 21.0 35.9 0.004 17.3 14.9 2.6 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KZN91443.1 - 0.016 14.4 18.3 0.024 13.8 18.3 1.2 1 0 0 1 1 1 0 UAA transporter family PUNUT PF16913.5 KZN91443.1 - 0.091 12.0 19.2 0.17 11.1 19.1 1.5 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport Glyco_hydro_15 PF00723.21 KZN91444.1 - 5.3e-49 167.2 0.0 7.7e-47 160.1 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 F-box-like PF12937.7 KZN91445.1 - 0.00028 20.7 0.1 0.00085 19.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN91445.1 - 0.01 15.7 0.3 0.037 13.9 0.1 2.1 2 0 0 2 2 2 0 F-box domain Sugar_tr PF00083.24 KZN91446.1 - 1.3e-122 409.9 13.3 1.9e-122 409.4 13.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN91446.1 - 9.8e-29 100.4 26.5 1.3e-22 80.2 10.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KZN91446.1 - 0.013 13.9 3.6 0.06 11.7 0.6 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Proton_antipo_N PF00662.20 KZN91446.1 - 0.14 12.3 0.8 30 4.8 0.0 3.2 3 0 0 3 3 3 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Pkr1 PF08636.10 KZN91447.1 - 4.6e-30 103.6 5.6 5.8e-30 103.2 5.6 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Phage_Gp23 PF10669.9 KZN91447.1 - 0.0069 16.7 2.0 0.024 14.9 2.0 1.8 1 1 0 1 1 1 1 Protein gp23 (Bacteriophage A118) PepSY_TM PF03929.16 KZN91447.1 - 0.059 13.0 0.1 0.069 12.8 0.1 1.2 1 0 0 1 1 1 0 PepSY-associated TM region FHIPEP PF00771.20 KZN91447.1 - 0.078 11.4 0.1 0.088 11.3 0.1 1.0 1 0 0 1 1 1 0 FHIPEP family Mem_trans PF03547.18 KZN91447.1 - 0.1 11.0 0.0 0.11 10.9 0.0 1.0 1 0 0 1 1 1 0 Membrane transport protein Cullin PF00888.22 KZN91448.1 - 1.3e-22 80.2 2.4 2e-22 79.6 2.4 1.2 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 KZN91448.1 - 2.3e-22 79.3 0.0 1.5e-21 76.7 0.0 2.3 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 TauD PF02668.16 KZN91449.1 - 2.1e-29 103.2 0.0 2.7e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family GATase PF00117.28 KZN91450.1 - 0.0042 16.9 0.0 0.0061 16.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Lactonase PF10282.9 KZN91452.1 - 1.7e-81 274.2 0.0 2e-81 274.0 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller He_PIG PF05345.12 KZN91452.1 - 0.065 13.4 3.2 0.08 13.1 0.4 2.6 3 0 0 3 3 3 0 Putative Ig domain 3HCDH_N PF02737.18 KZN91453.1 - 6.9e-27 94.5 0.0 2.5e-26 92.7 0.0 1.8 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KZN91453.1 - 2.4e-11 44.1 0.0 4.3e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Pyr_redox_2 PF07992.14 KZN91453.1 - 0.015 14.6 0.0 0.04 13.1 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ldl_recept_b PF00058.17 KZN91453.1 - 0.046 14.2 0.7 14 6.3 0.0 3.4 4 0 0 4 4 4 0 Low-density lipoprotein receptor repeat class B Pyr_redox PF00070.27 KZN91453.1 - 0.14 12.8 0.0 0.45 11.1 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NHL PF01436.21 KZN91453.1 - 0.15 12.2 0.0 1.6 8.9 0.0 2.7 2 0 0 2 2 2 0 NHL repeat DUF3716 PF12511.8 KZN91454.1 - 1.9e-11 43.8 2.2 3.3e-11 43.0 2.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF987 PF06174.11 KZN91454.1 - 0.067 13.1 0.0 0.29 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF987) CCDC53 PF10152.9 KZN91454.1 - 0.44 11.0 4.3 0.85 10.0 2.4 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Chal_sti_synt_N PF00195.19 KZN91455.1 - 2.7e-14 53.1 0.1 3.4e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain FAE1_CUT1_RppA PF08392.12 KZN91455.1 - 0.032 13.5 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein DUF4158 PF13700.6 KZN91455.1 - 0.073 12.9 0.0 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4158) IU_nuc_hydro PF01156.19 KZN91456.1 - 7.2e-42 144.0 0.0 8.5e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase GMC_oxred_N PF00732.19 KZN91457.1 - 4.9e-54 183.7 0.0 6.4e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KZN91457.1 - 2.4e-30 106.0 0.1 4.4e-30 105.1 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KZN91457.1 - 6.5e-05 22.1 0.0 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KZN91457.1 - 7.7e-05 22.4 0.0 0.072 12.7 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KZN91457.1 - 0.0008 19.6 0.0 0.0021 18.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KZN91457.1 - 0.0024 17.2 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KZN91457.1 - 0.0034 16.6 0.0 0.12 11.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KZN91457.1 - 0.0076 15.4 0.0 0.51 9.4 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 KZN91457.1 - 0.075 11.7 0.0 0.89 8.2 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 KZN91457.1 - 0.083 12.0 0.0 0.35 9.9 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain Metallophos PF00149.28 KZN91459.1 - 3.6e-17 63.5 0.0 7.7e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 KZN91459.1 - 5.7e-16 59.1 0.0 1.5e-15 57.7 0.0 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 KZN91459.1 - 9e-13 48.6 2.4 2.1e-12 47.4 2.4 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 KZN91459.1 - 0.00021 21.8 0.1 0.00043 20.8 0.1 1.5 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain ADD_DNMT3 PF17980.1 KZN91459.1 - 0.19 11.8 0.9 25 5.0 0.1 2.6 2 0 0 2 2 2 0 Cysteine rich ADD domain in DNMT3 MFS_1 PF07690.16 KZN91460.1 - 3.8e-32 111.6 31.5 3.8e-32 111.6 31.5 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily YwcE PF17368.2 KZN91460.1 - 0.79 10.4 0.0 0.79 10.4 0.0 3.0 4 0 0 4 4 4 0 Spore morphogenesis and germination YwcE CMAS PF02353.20 KZN91461.1 - 8.1e-58 195.9 1.2 1e-57 195.6 1.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KZN91461.1 - 3.3e-10 40.5 0.0 6.3e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN91461.1 - 8.4e-09 36.0 0.0 1.6e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN91461.1 - 1.3e-08 34.9 0.0 2.2e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN91461.1 - 0.00011 22.9 0.0 0.00021 22.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KZN91461.1 - 0.0038 16.8 0.0 0.0065 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.13 KZN91461.1 - 0.0044 16.6 0.0 0.0073 15.8 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 KZN91461.1 - 0.02 14.7 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KZN91461.1 - 0.025 14.6 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KZN91461.1 - 0.082 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Vac17 PF17321.2 KZN91462.1 - 0.025 14.1 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Vacuole-related protein 17 Aldo_ket_red PF00248.21 KZN91465.1 - 3.4e-36 125.0 0.0 6.4e-36 124.1 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family Stealth_CR3 PF17102.5 KZN91465.1 - 0.03 14.2 0.0 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 Stealth protein CR3, conserved region 3 adh_short_C2 PF13561.6 KZN91466.1 - 1.9e-80 269.8 0.5 6.5e-53 179.7 0.1 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN91466.1 - 1.7e-54 184.3 2.8 1.7e-45 154.9 0.5 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KZN91466.1 - 1.1e-05 25.5 0.1 2.2e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KZN91467.1 - 1.1e-51 175.7 0.2 1.4e-51 175.3 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN91467.1 - 6.3e-41 140.0 0.8 7.9e-41 139.7 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN91467.1 - 8.3e-09 35.6 0.6 1.3e-08 35.0 0.6 1.2 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.16 KZN91468.1 - 8.8e-18 64.3 54.8 1.3e-12 47.3 26.1 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN91468.1 - 2.5e-05 23.3 8.5 2.5e-05 23.3 8.5 3.2 3 1 1 4 4 4 2 Sugar (and other) transporter GMC_oxred_C PF05199.13 KZN91469.1 - 4.5e-31 108.3 0.0 7.2e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KZN91469.1 - 1.8e-27 96.5 0.0 4.7e-23 82.0 0.0 3.1 2 1 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.6 KZN91469.1 - 0.0025 18.0 0.2 0.0074 16.5 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KZN91469.1 - 0.012 14.9 0.0 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KZN91469.1 - 0.021 13.9 0.1 0.038 13.1 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Glyco_hydro_43 PF04616.14 KZN91470.1 - 9.9e-07 28.3 0.6 9.9e-07 28.3 0.6 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 Asp PF00026.23 KZN91471.1 - 1.2e-36 126.8 5.2 1.5e-36 126.4 5.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KZN91471.1 - 0.018 15.2 0.6 0.29 11.4 0.6 2.5 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KZN91471.1 - 0.038 13.8 0.1 0.074 12.8 0.1 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KZN91471.1 - 0.05 14.2 0.1 0.85 10.3 0.0 2.6 2 0 0 2 2 2 0 Aspartyl protease NAD_binding_4 PF07993.12 KZN91472.1 - 2.4e-39 135.1 0.0 3.4e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KZN91472.1 - 4.7e-34 117.7 0.0 5e-33 114.3 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KZN91472.1 - 3e-09 36.7 0.0 5.3e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KZN91472.1 - 0.0002 21.6 0.0 0.00061 20.1 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site PAX PF00292.18 KZN91472.1 - 0.041 13.8 0.0 0.87 9.5 0.0 2.6 3 0 0 3 3 3 0 'Paired box' domain KR PF08659.10 KZN91472.1 - 0.13 12.1 0.0 0.54 10.2 0.0 2.1 1 1 0 1 1 1 0 KR domain GMC_oxred_N PF00732.19 KZN91474.1 - 4.9e-64 216.5 0.0 6.7e-64 216.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KZN91474.1 - 4e-34 118.2 0.0 1.2e-33 116.6 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KZN91474.1 - 3e-05 23.4 0.0 0.00031 20.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KZN91474.1 - 3.1e-05 23.3 0.0 0.032 13.3 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KZN91474.1 - 4.3e-05 23.7 0.1 9.8e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KZN91474.1 - 0.00025 20.2 0.1 0.00041 19.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KZN91474.1 - 0.00099 18.4 0.2 0.59 9.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KZN91474.1 - 0.0011 18.6 0.3 0.026 14.1 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KZN91474.1 - 0.013 14.7 0.0 0.2 10.9 0.1 2.1 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 KZN91474.1 - 0.2 11.6 0.3 0.48 10.4 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Mannitol_dh_C PF08125.13 KZN91475.1 - 1.9e-74 250.2 0.0 6.3e-74 248.5 0.0 1.8 2 0 0 2 2 2 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KZN91475.1 - 1.3e-41 142.3 0.0 2.7e-41 141.2 0.0 1.6 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain PIR PF00399.19 KZN91475.1 - 0.066 12.8 0.3 0.12 12.0 0.3 1.4 1 0 0 1 1 1 0 Yeast PIR protein repeat Glyco_hydro_72 PF03198.14 KZN91476.1 - 5.5e-131 436.5 5.9 6.8e-131 436.2 5.9 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KZN91476.1 - 9.1e-20 71.1 1.4 2.3e-19 69.8 1.4 1.7 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 KZN91476.1 - 0.00072 19.1 0.3 0.0018 17.8 0.3 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KZN91476.1 - 0.0012 18.1 1.8 0.0036 16.5 1.8 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Yae1_N PF09811.9 KZN91477.1 - 2.4e-09 36.7 43.8 3.9e+02 0.8 0.1 8.4 3 1 0 3 3 3 0 Essential protein Yae1, N terminal MspA PF09203.11 KZN91477.1 - 0.0014 18.5 4.7 1.8 8.4 4.6 2.8 1 1 0 1 1 1 1 MspA Keratin_2_head PF16208.5 KZN91477.1 - 0.34 11.0 32.0 2.4e+02 1.8 13.7 3.7 1 1 1 2 2 2 0 Keratin type II head KRTAP PF11759.8 KZN91477.1 - 6.1 7.5 36.8 1.1e+04 -3.0 36.8 3.7 1 1 0 1 1 1 0 Keratin-associated matrix Pkinase_Tyr PF07714.17 KZN91478.1 - 1.6e-20 73.5 0.0 3.6e-20 72.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KZN91478.1 - 7.6e-20 71.4 0.0 1.9e-19 70.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KZN91478.1 - 0.019 14.5 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KZN91478.1 - 0.05 12.9 0.1 0.089 12.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KZN91478.1 - 0.16 11.8 0.4 0.4 10.6 0.2 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Glyco_hydro_16 PF00722.21 KZN91479.1 - 3e-05 23.6 0.3 7.1e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 NAD_binding_4 PF07993.12 KZN91480.1 - 7.6e-30 103.9 0.0 1.2e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KZN91480.1 - 1.8e-27 96.0 0.0 3.2e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KZN91480.1 - 1e-11 44.8 0.0 1.8e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KZN91480.1 - 1.5e-08 34.8 0.0 4e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 KZN91480.1 - 0.0031 17.0 0.0 0.014 14.8 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Glu_dehyd_C PF16912.5 KZN91480.1 - 0.021 14.3 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus 3Beta_HSD PF01073.19 KZN91480.1 - 0.034 13.1 0.0 0.099 11.6 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KZN91480.1 - 0.037 13.2 0.0 0.074 12.2 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KZN91480.1 - 0.074 12.1 0.0 0.84 8.7 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain KR PF08659.10 KZN91480.1 - 0.086 12.7 0.0 0.93 9.4 0.0 2.2 1 1 0 1 1 1 0 KR domain Methyltransf_2 PF00891.18 KZN91481.1 - 1e-18 67.4 0.0 2.1e-18 66.4 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KZN91481.1 - 0.0047 16.9 0.0 0.0096 15.9 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain Dimerisation PF08100.11 KZN91481.1 - 0.088 12.8 1.3 0.34 11.0 1.3 2.0 1 1 0 1 1 1 0 Dimerisation domain BcrAD_BadFG PF01869.20 KZN91482.1 - 3.9e-14 52.8 1.5 8.9e-14 51.6 1.5 1.6 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family SIS_2 PF13580.6 KZN91482.1 - 0.012 15.6 0.0 0.061 13.3 0.0 2.2 1 1 0 1 1 1 0 SIS domain SIS PF01380.22 KZN91482.1 - 0.14 12.1 0.5 0.53 10.1 0.0 2.2 2 0 0 2 2 2 0 SIS domain MFS_1 PF07690.16 KZN91483.1 - 2.6e-15 56.2 37.3 2.6e-15 56.2 37.3 1.9 2 1 1 3 3 3 1 Major Facilitator Superfamily UNC-93 PF05978.16 KZN91483.1 - 7.4e-09 35.5 3.9 7.4e-09 35.5 3.9 3.1 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 DUF3433 PF11915.8 KZN91487.1 - 2.2e-33 114.5 20.7 1.1e-18 67.4 3.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) IncD PF17628.2 KZN91487.1 - 0.11 12.3 0.5 16 5.3 0.1 2.9 2 0 0 2 2 2 0 Inclusion membrane protein D ApbA PF02558.16 KZN91488.1 - 1.1e-35 122.5 0.0 1.5e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KZN91488.1 - 9.1e-29 100.2 0.0 1.4e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Phage_holin_7_1 PF16081.5 KZN91488.1 - 0.01 16.0 0.1 0.02 15.0 0.1 1.4 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Sacchrp_dh_NADP PF03435.18 KZN91488.1 - 0.016 15.4 0.1 0.07 13.4 0.1 2.0 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FMN_dh PF01070.18 KZN91489.1 - 2.3e-115 385.3 0.0 2.8e-115 385.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KZN91489.1 - 7.5e-17 61.2 0.0 3.2e-15 56.0 0.0 2.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KZN91489.1 - 2e-06 27.2 0.0 3.8e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KZN91489.1 - 1.7e-05 24.0 0.4 0.00022 20.4 0.1 2.2 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 KZN91489.1 - 0.04 13.1 0.1 0.085 12.1 0.1 1.7 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase ThiG PF05690.14 KZN91489.1 - 0.047 13.0 0.1 10 5.4 0.0 2.4 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KZN91489.1 - 0.13 11.7 0.0 1.2 8.5 0.0 2.2 3 0 0 3 3 3 0 Histidine biosynthesis protein MR_MLE_C PF13378.6 KZN91490.1 - 1.2e-56 191.8 0.0 1.5e-56 191.4 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KZN91490.1 - 2.2e-19 69.8 0.0 4.3e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF1990 PF09348.10 KZN91490.1 - 0.097 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1990) MAAL_C PF07476.11 KZN91490.1 - 0.14 11.3 0.0 0.41 9.8 0.0 1.7 1 1 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Glyco_hydro_71 PF03659.14 KZN91491.1 - 5.3e-131 436.9 2.5 6.3e-131 436.6 2.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 CN_hydrolase PF00795.22 KZN91493.1 - 6.9e-47 160.0 0.0 8.4e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CIA30 PF08547.12 KZN91494.1 - 1.4e-40 138.9 0.0 1.7e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) MFS_1 PF07690.16 KZN91495.1 - 9.3e-40 136.6 44.2 9.3e-40 136.6 44.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN91495.1 - 2e-08 33.5 17.1 2e-08 33.5 17.1 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter Glyco_hydro_76 PF03663.14 KZN91496.1 - 9.5e-143 476.1 24.8 1.1e-142 475.9 24.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Steroid_dh PF02544.16 KZN91496.1 - 0.023 14.7 3.5 1.7 8.7 0.0 3.2 2 1 1 3 3 3 0 3-oxo-5-alpha-steroid 4-dehydrogenase COesterase PF00135.28 KZN91497.1 - 7.1e-87 292.4 0.0 8.3e-87 292.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KZN91497.1 - 3.2e-06 27.2 0.0 6.8e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KZN91497.1 - 0.012 15.0 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ig_GlcNase PF18368.1 KZN91498.1 - 4.2e-32 110.4 0.2 2.6e-31 107.9 0.1 2.3 2 0 0 2 2 2 1 Exo-beta-D-glucosaminidase Ig-fold domain Glyco_hydro_2 PF00703.21 KZN91498.1 - 1.5e-12 48.1 1.8 2.5e-12 47.4 0.0 2.3 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Mannosidase_ig PF17786.1 KZN91498.1 - 1.5e-07 32.0 0.0 4.9e-07 30.3 0.0 2.0 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2_N PF02837.18 KZN91498.1 - 6.5e-05 22.9 0.0 0.0002 21.3 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 KZN91498.1 - 0.0053 15.9 0.0 0.0097 15.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Ig_mannosidase PF17753.1 KZN91498.1 - 0.016 15.0 0.0 0.047 13.5 0.0 1.8 1 0 0 1 1 1 0 Ig-fold domain Glyco_hydro_76 PF03663.14 KZN91499.1 - 1.8e-161 537.7 25.1 2.1e-161 537.5 25.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KZN91499.1 - 4.7e-06 25.9 11.5 0.031 13.4 0.2 3.2 1 1 2 3 3 3 3 Glycosyl Hydrolase Family 88 ADH_N PF08240.12 KZN91500.1 - 1.7e-25 89.0 0.3 5.5e-25 87.4 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN91500.1 - 4.8e-19 68.6 1.3 7.6e-19 68.0 1.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KZN91500.1 - 0.00011 23.2 0.0 0.0002 22.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_hydro_1 PF00232.18 KZN91501.1 - 7.3e-74 248.8 0.1 1.5e-71 241.2 0.1 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 adh_short PF00106.25 KZN91502.1 - 2e-29 102.5 0.0 2.8e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN91502.1 - 6.1e-24 84.9 0.0 7e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN91502.1 - 1.3e-08 34.9 0.1 1.6e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KZN91502.1 - 0.0002 20.9 0.5 0.00047 19.7 0.5 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KZN91502.1 - 0.075 12.4 0.1 1.3 8.4 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DFP PF04127.15 KZN91502.1 - 0.094 12.5 0.1 0.19 11.5 0.0 1.5 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Med17 PF10156.9 KZN91503.1 - 3.6e-99 332.6 0.1 4.6e-99 332.2 0.1 1.0 1 0 0 1 1 1 1 Subunit 17 of Mediator complex DAO PF01266.24 KZN91504.1 - 1.9e-40 139.6 0.2 2.2e-40 139.4 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KZN91504.1 - 3.1e-05 24.1 0.4 8.3e-05 22.7 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KZN91504.1 - 0.0015 17.9 0.0 0.0025 17.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KZN91504.1 - 0.0035 16.6 0.0 0.0051 16.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KZN91504.1 - 0.0045 17.0 0.0 0.008 16.2 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KZN91504.1 - 0.024 13.9 0.2 0.12 11.6 0.1 2.2 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KZN91504.1 - 0.19 10.8 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein PFK PF00365.20 KZN91506.1 - 2.3e-188 624.3 0.3 6.6e-103 343.9 0.1 2.1 2 0 0 2 2 2 2 Phosphofructokinase XylR_N PF06505.11 KZN91506.1 - 0.056 13.2 0.4 2.9 7.7 0.0 3.0 3 0 0 3 3 3 0 Activator of aromatic catabolism DAGK_cat PF00781.24 KZN91506.1 - 0.06 13.0 0.0 0.32 10.6 0.1 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain ISN1 PF06437.11 KZN91507.1 - 9e-167 555.1 0.0 1e-166 554.9 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase DUF4646 PF15496.6 KZN91508.1 - 3.8e-05 24.3 0.0 0.00013 22.5 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) Erf4 PF10256.9 KZN91508.1 - 0.17 12.0 0.0 0.46 10.6 0.0 1.7 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Sugar_tr PF00083.24 KZN91511.1 - 4e-79 266.6 21.7 4.8e-79 266.3 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN91511.1 - 4.4e-14 52.2 54.9 7.6e-12 44.8 27.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ELFV_dehydrog_N PF02812.18 KZN91511.1 - 0.046 13.6 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DUF2456 PF10445.9 KZN91511.1 - 0.11 12.6 3.1 2.7 8.1 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) MFS_1 PF07690.16 KZN91512.1 - 1.2e-30 106.7 30.5 1.6e-30 106.3 30.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MASE2 PF05230.11 KZN91512.1 - 0.13 12.4 5.0 0.98 9.5 0.4 2.8 2 0 0 2 2 2 0 MASE2 domain Fungal_trans PF04082.18 KZN91513.1 - 1.5e-12 47.1 0.4 3.7e-12 45.9 0.4 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN91513.1 - 1.2e-08 34.9 12.0 2.3e-08 34.0 12.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC2_membrane PF01061.24 KZN91514.1 - 2.6e-80 268.8 49.0 6.6e-46 156.4 18.1 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KZN91514.1 - 2.1e-36 125.4 0.0 2.5e-18 66.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KZN91514.1 - 7e-24 83.5 7.4 4.2e-21 74.6 0.0 3.9 4 0 0 4 4 4 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 KZN91514.1 - 5e-07 29.2 34.9 9.2e-07 28.3 15.7 2.7 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 KZN91514.1 - 5.1e-07 30.2 0.0 0.0008 19.8 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KZN91514.1 - 1.4e-06 28.4 0.0 0.41 10.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KZN91514.1 - 6.7e-05 22.9 0.1 0.0014 18.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KZN91514.1 - 0.00013 22.5 0.1 0.043 14.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.19 KZN91514.1 - 0.00038 20.0 0.0 0.21 11.0 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KZN91514.1 - 0.00083 19.0 0.2 0.025 14.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KZN91514.1 - 0.0034 17.0 0.4 0.074 12.6 0.0 2.5 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.6 KZN91514.1 - 0.01 16.1 0.1 0.44 10.8 0.1 2.9 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KZN91514.1 - 0.01 15.9 0.0 4.5 7.4 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 KZN91514.1 - 0.011 16.0 0.0 0.081 13.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KZN91514.1 - 0.011 15.6 0.2 0.46 10.4 0.1 3.0 4 0 0 4 4 2 0 NACHT domain AAA_33 PF13671.6 KZN91514.1 - 0.034 14.3 0.0 0.22 11.7 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KZN91514.1 - 0.057 13.1 0.0 0.9 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KZN91514.1 - 0.093 12.3 0.1 1.6 8.3 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 KZN91514.1 - 0.15 12.6 0.0 0.4 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KZN91514.1 - 0.17 11.8 0.0 16 5.3 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 KZN91514.1 - 0.17 11.6 0.0 3.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SurE PF01975.17 KZN91515.1 - 1.4e-32 113.0 0.3 1.9e-32 112.6 0.3 1.1 1 0 0 1 1 1 1 Survival protein SurE NPP1 PF05630.11 KZN91516.1 - 2.1e-60 204.2 0.0 2.4e-60 204.0 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Glyco_hydro_61 PF03443.14 KZN91517.1 - 1.6e-63 214.4 0.2 2.9e-63 213.5 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KZN91517.1 - 5.5e-13 48.6 8.3 1.8e-12 47.0 8.3 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain FSA_C PF10479.9 KZN91517.1 - 7.6 4.5 12.1 9.6 4.2 12.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus MFS_1 PF07690.16 KZN91518.1 - 4.7e-33 114.6 25.1 5.9e-33 114.2 25.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_88 PF07470.13 KZN91519.1 - 3.3e-96 322.4 3.7 3.8e-96 322.1 3.7 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 KZN91519.1 - 0.0021 16.7 0.1 0.0028 16.3 0.1 1.1 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_76 PF03663.14 KZN91519.1 - 0.21 11.1 8.2 8.9 5.7 3.5 3.0 1 1 2 3 3 3 0 Glycosyl hydrolase family 76 Amidohydro_1 PF01979.20 KZN91520.1 - 8.8e-74 248.9 0.2 1.2e-73 248.4 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KZN91520.1 - 1.5e-20 74.2 0.2 1.1e-15 58.1 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 KZN91520.1 - 0.0024 17.3 0.0 0.0054 16.1 0.0 1.6 1 1 0 1 1 1 1 Adenosine/AMP deaminase Aldedh PF00171.22 KZN91521.1 - 2.3e-139 464.9 0.0 2.8e-139 464.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MAGI_u5 PF16666.5 KZN91521.1 - 0.034 14.3 0.1 0.067 13.3 0.1 1.4 1 0 0 1 1 1 0 Unstructured region on MAGI P5CR_dimer PF14748.6 KZN91523.1 - 2e-34 118.0 1.2 2e-34 118.0 1.2 1.7 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KZN91523.1 - 6.6e-17 61.9 0.2 1.7e-16 60.6 0.2 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent MycE_N PF17843.1 KZN91523.1 - 0.0045 17.5 0.1 0.016 15.7 0.0 2.0 2 1 0 2 2 2 1 MycE methyltransferase N-terminal NAD_Gly3P_dh_N PF01210.23 KZN91523.1 - 0.015 15.3 0.3 0.042 13.8 0.0 1.9 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KZN91523.1 - 0.045 13.4 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA zinc_ribbon_10 PF10058.9 KZN91524.1 - 1.9e-18 65.9 0.1 3.3e-18 65.1 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Rubredoxin_2 PF18073.1 KZN91524.1 - 3.3 7.5 7.6 0.49 10.2 3.3 1.8 2 0 0 2 2 2 0 Rubredoxin metal binding domain Ribonuclease_3 PF00636.26 KZN91525.1 - 1.2e-41 141.6 0.0 6.9e-24 84.5 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KZN91525.1 - 1.5e-28 99.5 0.0 1.8e-13 50.8 0.0 3.6 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 KZN91525.1 - 6e-22 77.6 0.0 1.8e-21 76.1 0.0 1.9 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 KZN91525.1 - 3.2e-15 56.4 0.0 9.4e-15 54.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KZN91525.1 - 3.2e-14 53.1 0.0 1.1e-11 44.9 0.0 2.5 1 1 1 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 KZN91525.1 - 1.4e-08 34.9 0.0 5.8e-07 29.7 0.0 3.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF3050 PF11251.8 KZN91525.1 - 0.031 13.9 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3050) IstB_IS21 PF01695.17 KZN91525.1 - 0.071 12.8 0.0 0.27 10.9 0.0 2.0 1 0 0 1 1 1 0 IstB-like ATP binding protein COPI_C PF06957.11 KZN91526.1 - 0.03 13.1 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus DIOX_N PF14226.6 KZN91527.1 - 2e-21 76.9 0.0 3.2e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KZN91527.1 - 8.1e-13 48.7 0.0 1.3e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fructosamin_kin PF03881.14 KZN91527.1 - 0.04 13.1 0.0 0.058 12.6 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase Fungal_trans_2 PF11951.8 KZN91528.1 - 8.7e-51 172.9 4.5 1.1e-50 172.5 4.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain peroxidase PF00141.23 KZN91529.1 - 1.2e-80 270.6 0.0 1.1e-42 146.3 0.0 2.3 2 0 0 2 2 2 2 Peroxidase FAD_binding_3 PF01494.19 KZN91530.1 - 1.1e-25 90.7 0.0 1.4e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KZN91530.1 - 1.7e-05 24.6 0.4 0.00013 21.6 0.3 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KZN91530.1 - 1.9e-05 25.1 0.2 0.00075 20.0 0.2 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KZN91530.1 - 3.3e-05 23.3 0.5 0.00086 18.6 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN91530.1 - 0.0013 18.9 0.2 0.0054 16.9 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KZN91530.1 - 0.0032 16.9 0.3 0.0082 15.5 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KZN91530.1 - 0.0044 16.3 0.5 0.0063 15.8 0.5 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KZN91530.1 - 0.0064 15.6 2.0 0.0068 15.5 0.7 1.8 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 KZN91530.1 - 0.013 14.4 0.4 7 5.4 0.0 2.9 3 0 0 3 3 3 0 Tryptophan halogenase ApbA PF02558.16 KZN91530.1 - 0.017 14.8 0.3 0.029 14.0 0.3 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 KZN91530.1 - 0.039 13.0 0.7 0.054 12.6 0.7 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KZN91530.1 - 0.05 13.5 0.2 0.075 12.9 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.10 KZN91530.1 - 0.087 11.9 0.0 0.12 11.4 0.0 1.4 1 1 0 1 1 1 0 Squalene epoxidase TrkA_N PF02254.18 KZN91530.1 - 0.094 13.0 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Rossmann-like PF10727.9 KZN91530.1 - 0.2 11.5 0.1 0.35 10.7 0.1 1.4 1 0 0 1 1 1 0 Rossmann-like domain M20_dimer PF07687.14 KZN91535.1 - 2.3e-09 37.1 0.0 6.9e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KZN91535.1 - 1.8e-07 31.0 0.1 3.1e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 GMC_oxred_N PF00732.19 KZN91537.1 - 1.7e-55 188.5 0.0 2.2e-55 188.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KZN91537.1 - 1.3e-31 110.0 0.0 2.1e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KZN91537.1 - 4.4e-06 26.0 0.1 7e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KZN91537.1 - 1.4e-05 24.9 0.9 0.0019 17.9 0.1 2.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KZN91537.1 - 0.0002 20.7 0.3 0.22 10.7 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN91537.1 - 0.00058 20.0 0.2 0.0016 18.6 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KZN91537.1 - 0.0014 17.9 0.2 0.0047 16.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KZN91537.1 - 0.0055 15.8 0.2 1.8 7.6 0.2 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.14 KZN91537.1 - 0.0069 15.1 0.1 0.22 10.2 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KZN91537.1 - 0.032 13.3 3.2 0.062 12.4 0.5 2.3 2 1 0 2 2 2 0 FAD binding domain CBM_11 PF03425.13 KZN91537.1 - 0.039 13.8 0.1 0.071 13.0 0.1 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) NAD_binding_9 PF13454.6 KZN91537.1 - 0.087 12.8 0.3 0.25 11.3 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KZN91537.1 - 0.2 12.3 0.2 1.5 9.4 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase bZIP_1 PF00170.21 KZN91538.1 - 0.006 16.7 4.8 0.0098 16.0 4.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor Med4 PF10018.9 KZN91538.1 - 0.013 15.2 0.4 0.019 14.6 0.4 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 bZIP_1 PF00170.21 KZN91539.1 - 7.3e-10 38.8 10.6 2.2e-08 34.0 9.0 2.6 2 1 0 2 2 2 1 bZIP transcription factor BLOC1_2 PF10046.9 KZN91539.1 - 0.043 14.1 0.6 0.077 13.3 0.6 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_2 PF07716.15 KZN91539.1 - 0.11 12.6 12.8 2.6 8.2 10.2 3.0 2 1 0 2 2 2 0 Basic region leucine zipper Imm32 PF15566.6 KZN91539.1 - 0.26 11.1 0.6 3.7 7.4 0.0 2.5 3 0 0 3 3 3 0 Immunity protein 32 DUF2205 PF10224.9 KZN91539.1 - 0.45 10.5 2.2 0.9 9.6 2.2 1.4 1 0 0 1 1 1 0 Short coiled-coil protein Ribosomal_S20p PF01649.18 KZN91539.1 - 3.7 8.2 6.6 0.45 11.2 1.4 1.9 2 0 0 2 2 2 0 Ribosomal protein S20 Anoctamin PF04547.12 KZN91540.1 - 8.8e-117 390.7 4.9 1.1e-116 390.3 4.9 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Acetyltransf_1 PF00583.25 KZN91540.1 - 1.6e-15 57.3 0.0 2.2e-14 53.7 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KZN91540.1 - 2e-06 28.1 0.0 5.2e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KZN91540.1 - 3.2e-06 27.0 0.0 7.1e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KZN91540.1 - 0.00015 21.7 0.0 0.00036 20.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KZN91540.1 - 0.035 14.8 0.0 0.14 12.8 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GRIP PF01465.20 KZN91541.1 - 6e-17 61.3 0.2 1.3e-16 60.2 0.2 1.6 1 0 0 1 1 1 1 GRIP domain Spc7 PF08317.11 KZN91541.1 - 8.1e-09 34.8 141.7 0.0012 17.8 12.7 8.4 2 2 7 9 9 9 5 Spc7 kinetochore protein GAS PF13851.6 KZN91541.1 - 1.2e-07 31.2 139.9 0.03 13.7 13.1 9.9 3 2 5 8 8 8 4 Growth-arrest specific micro-tubule binding EzrA PF06160.12 KZN91541.1 - 2.7e-07 29.2 102.1 4.1e-06 25.3 44.0 4.5 2 2 1 4 4 4 3 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.9 KZN91541.1 - 5.1e-07 29.8 158.9 3.4e-05 23.9 9.9 10.6 3 2 7 10 10 10 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.8 KZN91541.1 - 0.00015 19.5 43.8 0.00015 19.5 43.8 5.5 2 2 3 5 5 5 4 Protein of unknown function (DUF3584) Fib_alpha PF08702.10 KZN91541.1 - 0.00047 20.3 85.7 0.016 15.4 12.4 8.4 3 1 5 8 8 8 6 Fibrinogen alpha/beta chain family DHR10 PF18595.1 KZN91541.1 - 0.00059 19.9 9.5 0.00059 19.9 9.5 11.8 4 2 6 11 11 9 2 Designed helical repeat protein 10 domain Fez1 PF06818.15 KZN91541.1 - 0.00065 20.2 140.1 0.48 10.9 9.6 8.2 2 2 5 7 7 6 3 Fez1 Cast PF10174.9 KZN91541.1 - 0.0011 17.3 22.4 0.0011 17.3 22.4 5.5 2 2 3 5 5 3 2 RIM-binding protein of the cytomatrix active zone FPP PF05911.11 KZN91541.1 - 0.002 16.4 17.8 0.002 16.4 17.8 6.2 2 2 5 7 7 7 2 Filament-like plant protein, long coiled-coil DUF4201 PF13870.6 KZN91541.1 - 0.003 17.3 5.2 0.003 17.3 5.2 11.1 3 3 9 12 12 12 5 Domain of unknown function (DUF4201) Baculo_PEP_C PF04513.12 KZN91541.1 - 0.0031 17.6 47.6 0.7 9.9 1.7 7.4 3 2 2 7 7 7 2 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.11 KZN91541.1 - 0.0051 17.1 163.3 0.45 10.7 6.7 9.5 3 2 5 8 8 8 4 Autophagy protein 16 (ATG16) CC2-LZ PF16516.5 KZN91541.1 - 0.0081 16.5 5.1 0.0081 16.5 5.1 12.4 3 2 4 10 10 10 3 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Golgin_A5 PF09787.9 KZN91541.1 - 0.023 14.1 134.4 0.17 11.3 17.0 7.8 2 2 6 8 8 8 0 Golgin subfamily A member 5 APG6_N PF17675.1 KZN91541.1 - 0.081 13.5 171.0 0.14 12.6 6.8 11.5 3 2 9 12 12 11 0 Apg6 coiled-coil region NPV_P10 PF05531.12 KZN91541.1 - 0.083 13.4 47.6 1.9 9.0 0.3 9.8 5 3 3 8 8 8 0 Nucleopolyhedrovirus P10 protein Filament PF00038.21 KZN91541.1 - 0.12 12.0 123.6 0.065 12.8 8.1 8.8 3 2 5 8 8 8 0 Intermediate filament protein TolA_bind_tri PF16331.5 KZN91541.1 - 0.49 10.5 80.9 1.5 8.9 4.1 12.1 4 4 7 11 11 11 0 TolA binding protein trimerisation AAA_13 PF13166.6 KZN91541.1 - 0.53 8.9 104.1 0.084 11.5 21.2 5.5 1 1 3 4 4 4 0 AAA domain FliJ PF02050.16 KZN91541.1 - 0.7 10.1 95.6 0.23 11.7 14.8 9.9 3 2 8 12 12 12 0 Flagellar FliJ protein SpoOE-like PF09388.10 KZN91541.1 - 1.6 8.7 8.3 0.53 10.2 0.6 4.2 3 0 0 3 3 3 0 Spo0E like sporulation regulatory protein HMMR_N PF15905.5 KZN91541.1 - 1.9 7.9 138.1 1.5 8.3 36.8 7.2 2 2 4 6 6 6 0 Hyaluronan mediated motility receptor N-terminal Desmo_N PF06771.11 KZN91541.1 - 2.4 8.6 9.8 1.3 9.5 0.0 4.5 5 0 0 5 5 4 0 Viral Desmoplakin N-terminus DUF1664 PF07889.12 KZN91541.1 - 3 7.9 84.0 1.1 9.3 6.6 11.0 3 2 9 13 13 13 0 Protein of unknown function (DUF1664) MscS_porin PF12795.7 KZN91541.1 - 3.2 7.2 129.3 0.055 13.0 21.4 7.3 3 2 3 7 7 7 0 Mechanosensitive ion channel porin domain DUF4407 PF14362.6 KZN91541.1 - 6.4 6.0 119.3 0.032 13.6 9.9 7.7 2 2 5 7 7 5 0 Domain of unknown function (DUF4407) DUF4763 PF15960.5 KZN91541.1 - 6.7 5.9 100.7 0.93 8.8 2.4 8.4 2 2 5 7 7 7 0 Domain of unknown function (DUF4763) cNMP_binding PF00027.29 KZN91542.1 - 1.5e-28 98.7 0.2 1.5e-17 63.4 0.0 5.7 6 0 0 6 6 6 3 Cyclic nucleotide-binding domain Patatin PF01734.22 KZN91542.1 - 4.5e-16 59.7 8.8 3.7e-15 56.7 5.8 2.9 2 1 0 2 2 2 1 Patatin-like phospholipase MARVEL PF01284.23 KZN91543.1 - 4.6e-16 59.2 10.4 5.9e-16 58.8 10.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF716 PF04819.12 KZN91543.1 - 0.002 17.8 2.8 0.0025 17.5 2.8 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF716) DUF5504 PF17608.2 KZN91543.1 - 0.0071 16.4 0.2 0.013 15.6 0.2 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5504) Ribosomal_S12 PF17487.2 KZN91543.1 - 0.065 14.0 1.2 0.065 14.0 1.2 2.0 3 0 0 3 3 3 0 Ribosomal protein S12 Ndc1_Nup PF09531.10 KZN91543.1 - 0.13 10.9 1.4 0.17 10.6 1.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Tetraspanin PF00335.20 KZN91543.1 - 0.55 9.9 0.0 0.55 9.9 0.0 2.0 2 0 0 2 2 2 0 Tetraspanin family Actin PF00022.19 KZN91544.1 - 9.3e-54 182.6 0.0 6.8e-29 100.7 0.0 2.2 2 0 0 2 2 2 2 Actin DASH_Dad4 PF08650.10 KZN91545.1 - 1.6e-32 111.3 7.6 1.7e-32 111.2 7.6 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 GM_CSF PF01109.17 KZN91545.1 - 0.05 13.8 0.3 0.052 13.7 0.3 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor Biotin_carb_C PF02785.19 KZN91545.1 - 0.12 12.5 0.1 0.13 12.3 0.1 1.1 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain YL1_C PF08265.11 KZN91546.1 - 7.5e-16 57.6 0.3 1.5e-15 56.6 0.3 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Got1 PF04178.12 KZN91547.1 - 4e-14 53.0 13.1 5.2e-14 52.6 13.1 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Profilin PF00235.19 KZN91548.1 - 3.5e-39 134.0 0.1 3.8e-39 133.8 0.1 1.0 1 0 0 1 1 1 1 Profilin Frankia_peptide PF14407.6 KZN91548.1 - 0.16 11.9 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Sec63 PF02889.16 KZN91550.1 - 4.2e-130 432.5 0.0 3.5e-81 272.1 0.0 2.6 2 1 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KZN91550.1 - 2.2e-52 177.4 0.4 8.8e-27 94.0 0.6 2.9 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 KZN91550.1 - 2.3e-22 79.8 0.0 4.5e-11 43.1 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KZN91550.1 - 1.1e-17 64.3 0.1 6.5e-07 29.7 0.0 4.5 4 2 0 4 4 4 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KZN91550.1 - 3.8e-09 36.9 0.1 0.0006 20.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KZN91550.1 - 2.7e-07 30.5 0.2 0.0059 16.3 0.3 2.5 2 0 0 2 2 2 2 AAA domain Helicase_PWI PF18149.1 KZN91550.1 - 7.1e-06 26.2 0.0 2.3e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 N-terminal helicase PWI domain AAA_19 PF13245.6 KZN91550.1 - 3.6e-05 24.1 0.6 0.0068 16.7 0.7 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KZN91550.1 - 0.046 13.4 0.3 3.9 7.2 0.0 3.3 4 0 0 4 4 4 0 IstB-like ATP binding protein PhoH PF02562.16 KZN91550.1 - 0.076 12.5 0.0 8.4 5.8 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein TniB PF05621.11 KZN91550.1 - 0.095 12.1 0.4 16 4.8 0.0 3.4 4 0 0 4 4 4 0 Bacterial TniB protein Synaptobrevin PF00957.21 KZN91551.1 - 6.5e-15 54.7 0.7 1.1e-14 54.0 0.7 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KZN91551.1 - 1.9e-11 43.8 0.0 4e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Peptidase_S15 PF02129.18 KZN91552.1 - 1.4e-41 142.8 1.0 1.8e-41 142.5 1.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KZN91552.1 - 2.1e-41 142.3 0.0 3.3e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 KZN91552.1 - 0.005 16.1 0.0 0.008 15.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 FAD_binding_3 PF01494.19 KZN91553.1 - 8e-24 84.5 0.1 1.1e-23 84.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain ADC PF06314.11 KZN91553.1 - 5.8e-09 35.9 0.0 1.7e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 Acetoacetate decarboxylase (ADC) NAD_binding_8 PF13450.6 KZN91553.1 - 3.5e-07 30.3 0.1 9.1e-07 29.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KZN91553.1 - 1.3e-06 27.9 1.6 0.00014 21.2 0.3 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KZN91553.1 - 0.00014 21.1 0.7 0.00014 21.1 0.7 1.8 1 1 1 2 2 2 1 FAD binding domain DAO PF01266.24 KZN91553.1 - 0.00071 19.2 0.1 0.0013 18.4 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KZN91553.1 - 0.0068 15.3 0.6 0.012 14.5 0.3 1.4 1 1 0 1 1 1 1 Tryptophan halogenase Pyr_redox PF00070.27 KZN91553.1 - 0.015 15.8 0.2 0.059 13.9 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KZN91553.1 - 0.036 13.2 0.2 0.052 12.6 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 KZN91553.1 - 0.048 12.9 0.5 0.14 11.4 0.1 1.8 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.21 KZN91553.1 - 0.049 12.9 0.2 0.086 12.1 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KZN91553.1 - 0.05 12.3 0.1 0.094 11.4 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 KZN91553.1 - 0.054 12.8 0.1 0.083 12.2 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KZN91553.1 - 0.14 11.4 0.5 0.25 10.6 0.5 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KZN91553.1 - 0.41 9.6 1.3 1.8 7.5 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein Fungal_trans PF04082.18 KZN91554.1 - 8.6e-12 44.6 0.0 1.4e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KZN91554.1 - 1.4e-10 41.0 10.2 9.7e-06 25.8 0.7 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KZN91554.1 - 3.4e-07 30.4 12.1 1.3e-06 28.5 5.1 3.5 3 0 0 3 3 3 1 Zinc-finger double domain Zn_clus PF00172.18 KZN91554.1 - 4.4e-05 23.5 12.3 4.4e-05 23.5 12.3 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 KZN91554.1 - 0.00026 21.6 18.3 0.006 17.3 0.8 3.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.7 KZN91554.1 - 0.032 14.6 4.0 1.9 9.0 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KZN91554.1 - 0.094 13.0 1.9 2.2 8.7 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 KZN91554.1 - 0.18 12.3 3.6 3.1 8.3 0.1 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Cupin_2 PF07883.11 KZN91555.1 - 1.5e-09 37.4 0.0 2.4e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KZN91555.1 - 0.00074 19.2 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.22 KZN91555.1 - 0.02 14.5 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Cupin FAA_hydrolase PF01557.18 KZN91556.1 - 6.9e-56 189.3 0.0 8.9e-56 189.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KZN91556.1 - 3.4e-18 65.8 0.1 8.5e-18 64.5 0.0 1.6 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal MFS_1 PF07690.16 KZN91557.1 - 6.3e-38 130.6 31.7 9.5e-37 126.7 30.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN91557.1 - 9.3e-17 61.0 7.3 1.7e-16 60.2 7.3 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KZN91557.1 - 2.1e-07 29.8 4.8 3.4e-07 29.1 4.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CPP1-like PF11833.8 KZN91557.1 - 0.095 12.4 10.0 1.6 8.3 3.4 2.8 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like LigB PF02900.18 KZN91558.1 - 4.1e-14 52.3 0.0 4.8e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Aldedh PF00171.22 KZN91560.1 - 2e-15 56.3 0.1 4.4e-09 35.4 0.1 2.7 3 0 0 3 3 3 2 Aldehyde dehydrogenase family Cupin_2 PF07883.11 KZN91562.1 - 1.2e-07 31.3 0.1 1.7e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KZN91562.1 - 0.028 14.0 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Cupin Sugar_tr PF00083.24 KZN91563.1 - 9.6e-52 176.3 25.5 1.1e-51 176.2 25.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN91563.1 - 1.2e-16 60.6 39.1 1.5e-16 60.3 33.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KZN91563.1 - 0.045 12.3 35.9 0.012 14.2 10.2 3.9 2 2 2 4 4 4 0 MFS/sugar transport protein RhodobacterPufX PF11511.8 KZN91563.1 - 0.14 11.8 0.3 0.14 11.8 0.3 2.7 3 0 0 3 3 3 0 Intrinsic membrane protein PufX SLC3A2_N PF16028.5 KZN91564.1 - 0.018 14.6 7.6 0.43 10.2 0.1 3.0 3 0 0 3 3 3 0 Solute carrier family 3 member 2 N-terminus DUF2207 PF09972.9 KZN91564.1 - 0.021 13.6 0.0 0.021 13.6 0.0 2.4 3 1 0 3 3 3 0 Predicted membrane protein (DUF2207) PI3K_P85_iSH2 PF16454.5 KZN91564.1 - 0.16 11.6 0.2 0.25 10.9 0.2 1.1 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FAD_binding_4 PF01565.23 KZN91566.1 - 3.7e-22 78.5 0.0 5.9e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KZN91566.1 - 2.4e-05 24.3 0.1 2.4e-05 24.3 0.1 2.4 2 0 0 2 2 2 1 Berberine and berberine like SSF PF00474.17 KZN91567.1 - 2e-25 89.5 31.6 2.9e-25 89.0 31.6 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family DUF5394 PF17372.2 KZN91567.1 - 0.002 17.7 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5394) ADH_N PF08240.12 KZN91568.1 - 7.9e-06 25.7 0.0 2.7e-05 24.0 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN91568.1 - 0.0049 16.9 0.2 0.011 15.7 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase LRR_adjacent PF08191.11 KZN91568.1 - 0.12 12.6 0.0 0.39 11.0 0.0 1.8 2 0 0 2 2 2 0 LRR adjacent DUF3431 PF11913.8 KZN91569.1 - 4.8e-83 278.2 0.0 5.9e-83 277.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) KAR9 PF08580.10 KZN91570.1 - 0.091 11.3 12.8 0.14 10.7 12.8 1.3 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Ras PF00071.22 KZN91571.1 - 2.2e-16 59.9 0.0 7.4e-09 35.4 0.0 3.0 2 1 1 3 3 3 2 Ras family Roc PF08477.13 KZN91571.1 - 3.7e-13 49.8 0.1 1.4e-10 41.4 0.0 2.2 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KZN91571.1 - 0.014 15.8 0.0 0.029 14.8 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain Herpes_capsid PF06112.11 KZN91571.1 - 0.02 14.9 4.7 0.037 14.1 4.7 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein AAA_33 PF13671.6 KZN91571.1 - 0.053 13.7 0.0 0.089 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KZN91571.1 - 0.075 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 KZN91571.1 - 0.097 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KZN91571.1 - 0.1 12.9 0.0 0.24 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KZN91571.1 - 0.12 12.8 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KZN91571.1 - 0.15 12.3 0.2 0.58 10.4 0.1 1.9 2 1 1 3 3 3 0 AAA domain SRPRB PF09439.10 KZN91571.1 - 0.15 11.4 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 KZN91571.1 - 0.17 12.0 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 KZN91571.1 - 0.21 11.0 0.0 0.46 9.9 0.0 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_7 PF12775.7 KZN91571.1 - 0.23 11.0 0.1 0.35 10.4 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Sugar_tr PF00083.24 KZN91572.1 - 7.5e-103 344.8 26.0 8.8e-103 344.6 26.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN91572.1 - 1.6e-24 86.5 38.0 2.9e-14 52.8 11.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.12 KZN91572.1 - 0.23 11.6 0.0 0.23 11.6 0.0 3.2 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 FMN_dh PF01070.18 KZN91573.1 - 1.3e-122 409.2 0.1 1.6e-122 408.9 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KZN91573.1 - 6.8e-24 83.8 0.1 1.7e-23 82.5 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KZN91573.1 - 6.4e-07 28.8 0.1 1e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KZN91573.1 - 0.00011 21.7 0.1 0.0002 20.9 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KZN91573.1 - 0.00027 20.1 0.1 0.00076 18.6 0.0 1.6 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KZN91573.1 - 0.036 13.5 0.3 1.2 8.5 0.1 2.4 1 1 0 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.14 KZN91573.1 - 0.053 12.8 0.0 8 5.7 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DUF561 PF04481.12 KZN91573.1 - 0.094 11.9 0.1 2.3 7.3 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF561) Metallophos PF00149.28 KZN91574.1 - 6.1e-11 43.2 0.3 2e-10 41.5 0.3 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KZN91574.1 - 7.3e-05 23.0 1.9 0.0025 18.1 0.4 2.2 1 1 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 KZN91575.1 - 5.7e-42 143.9 0.3 1.5e-22 80.2 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KZN91575.1 - 7.8e-15 54.9 0.6 2.9e-10 39.9 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KZN91575.1 - 0.037 12.8 0.0 0.062 12.1 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Phage_Gp23 PF10669.9 KZN91575.1 - 0.26 11.6 1.2 0.39 11.1 0.1 1.8 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) SH3-RhoG_link PF16609.5 KZN91575.1 - 6.3 6.5 10.5 0.07 12.9 0.6 2.4 2 1 0 3 3 3 0 SH3-RhoGEF linking unstructured region DNA_binding_1 PF01035.20 KZN91576.1 - 1.8e-23 82.5 0.1 2.3e-23 82.1 0.1 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Bud13 PF09736.9 KZN91577.1 - 2.6e-47 160.9 8.9 2.6e-47 160.9 8.9 2.9 3 1 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex SPATIAL PF15256.6 KZN91577.1 - 0.24 11.7 4.2 0.47 10.7 4.2 1.6 1 0 0 1 1 1 0 SPATIAL CENP-Q PF13094.6 KZN91577.1 - 0.58 10.3 11.0 0.051 13.8 4.6 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Brr6_like_C_C PF10104.9 KZN91578.1 - 1.2e-42 144.8 1.3 1.6e-42 144.4 1.3 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain MFS_1 PF07690.16 KZN91579.1 - 6.9e-31 107.4 47.3 6.9e-31 107.4 47.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN91579.1 - 3.6e-08 32.7 39.7 1.6e-07 30.5 13.5 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter Glyco_transf_20 PF00982.21 KZN91580.1 - 6.9e-156 519.6 0.0 8e-156 519.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.6 KZN91580.1 - 0.00037 20.9 0.0 0.0011 19.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 DUF693 PF05113.13 KZN91580.1 - 0.0039 16.5 0.0 0.006 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF693) Glycos_transf_1 PF00534.20 KZN91580.1 - 0.0056 16.2 0.5 0.096 12.2 0.5 2.6 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KZN91580.1 - 0.0065 16.8 0.0 0.021 15.2 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 AA_permease PF00324.21 KZN91581.1 - 2.7e-134 448.3 40.7 3.3e-134 448.1 40.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KZN91581.1 - 2.3e-35 122.3 44.5 2.7e-35 122.0 44.5 1.0 1 0 0 1 1 1 1 Amino acid permease PMBR PF09373.10 KZN91581.1 - 0.043 14.0 0.0 0.086 13.0 0.0 1.5 1 0 0 1 1 1 0 Pseudomurein-binding repeat Ribonuclease PF00545.20 KZN91582.1 - 6.6e-10 39.6 0.1 8.3e-10 39.3 0.1 1.2 1 0 0 1 1 1 1 ribonuclease MF_alpha_N PF05436.11 KZN91582.1 - 0.034 14.0 0.1 0.059 13.3 0.1 1.4 1 1 0 1 1 1 0 Mating factor alpha precursor N-terminus GST_N_3 PF13417.6 KZN91583.1 - 6e-12 45.8 0.0 1.3e-11 44.7 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KZN91583.1 - 7.7e-12 45.4 0.2 2e-11 44.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KZN91583.1 - 1.6e-10 41.0 0.1 2.6e-10 40.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KZN91583.1 - 6e-09 36.0 0.1 1.1e-08 35.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KZN91583.1 - 1.7e-07 31.4 0.0 3.2e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KZN91583.1 - 9.6e-05 22.3 0.1 0.00017 21.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KZN91583.1 - 0.00088 19.8 0.1 0.0092 16.6 0.0 2.1 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KZN91583.1 - 0.0094 16.7 0.0 0.04 14.7 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain Methyltransf_31 PF13847.6 KZN91584.1 - 4.5e-29 101.2 0.0 6e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN91584.1 - 1.7e-25 89.5 0.0 2.9e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN91584.1 - 2e-24 86.1 0.0 3.1e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KZN91584.1 - 3e-20 72.6 0.0 4.3e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KZN91584.1 - 1.4e-16 60.8 0.0 2e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN91584.1 - 1.3e-15 57.9 0.0 2.2e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KZN91584.1 - 2e-08 34.0 0.0 3.3e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 KZN91584.1 - 2.9e-07 30.2 0.0 4.2e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KZN91584.1 - 4.2e-06 26.7 0.0 5.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 KZN91584.1 - 0.00017 21.1 0.0 0.00025 20.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_9 PF08003.11 KZN91584.1 - 0.00048 19.2 0.0 0.00073 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) NodS PF05401.11 KZN91584.1 - 0.00052 19.7 0.0 0.00077 19.1 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_18 PF12847.7 KZN91584.1 - 0.0016 18.4 0.0 0.0028 17.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KZN91584.1 - 0.0023 18.1 0.0 0.0031 17.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase DREV PF05219.12 KZN91584.1 - 0.0049 16.0 0.0 0.011 14.9 0.0 1.5 1 1 0 1 1 1 1 DREV methyltransferase Methyltransf_32 PF13679.6 KZN91584.1 - 0.0055 16.7 0.0 0.0077 16.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KZN91584.1 - 0.007 15.7 0.0 0.009 15.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.14 KZN91584.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_8 PF05148.15 KZN91584.1 - 0.028 14.3 0.0 0.35 10.7 0.0 2.0 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_29 PF03141.16 KZN91584.1 - 0.033 12.8 0.0 0.059 11.9 0.0 1.4 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CheR PF01739.18 KZN91584.1 - 0.046 13.2 0.0 2 7.9 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain RrnaAD PF00398.20 KZN91584.1 - 0.059 12.4 0.0 0.074 12.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase GCD14 PF08704.10 KZN91584.1 - 0.066 12.9 0.0 0.095 12.4 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit PrmA PF06325.13 KZN91584.1 - 0.087 12.2 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) WW PF00397.26 KZN91585.1 - 1.4e-06 28.3 0.5 1.4e-06 28.3 0.5 2.2 2 0 0 2 2 2 1 WW domain Na_Ca_ex PF01699.24 KZN91586.1 - 1.1e-39 135.8 39.8 7e-20 71.5 19.3 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein CorA PF01544.18 KZN91587.1 - 7.5e-38 130.5 0.0 9.1e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Anoctamin PF04547.12 KZN91588.1 - 4.7e-70 236.7 0.0 6e-70 236.3 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Ferric_reduct PF01794.19 KZN91589.1 - 0.16 12.1 2.0 3 8.0 0.2 2.7 2 1 0 2 2 2 0 Ferric reductase like transmembrane component YbgT_YccB PF08173.11 KZN91589.1 - 5.6 7.2 6.7 0.63 10.2 1.5 2.1 2 0 0 2 2 2 0 Membrane bound YbgT-like protein Transp_cyt_pur PF02133.15 KZN91590.1 - 3.5e-84 283.1 42.9 4e-84 282.9 42.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Ldr_toxin PF13940.6 KZN91590.1 - 0.016 15.2 1.5 0.016 15.2 1.5 2.6 2 0 0 2 2 2 0 Toxin Ldr, type I toxin-antitoxin system TauD PF02668.16 KZN91591.1 - 6e-25 88.5 0.0 7.9e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KZN91591.1 - 0.097 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 CsiD PEP_mutase PF13714.6 KZN91592.1 - 1.6e-26 93.3 0.0 4.2e-17 62.4 0.0 2.0 1 1 1 2 2 2 2 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KZN91592.1 - 8.4e-12 44.3 0.0 1.1e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Dynactin_p62 PF05502.13 KZN91592.1 - 0.046 12.5 0.0 0.054 12.3 0.0 1.1 1 0 0 1 1 1 0 Dynactin p62 family Fungal_trans PF04082.18 KZN91593.1 - 7.4e-20 71.1 2.0 3e-19 69.1 2.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN91593.1 - 5.7e-09 35.9 10.5 1.1e-08 35.1 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Polysacc_deac_1 PF01522.21 KZN91594.1 - 1.4e-08 34.7 0.0 2.3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Amidase PF01425.21 KZN91595.1 - 4.7e-83 279.6 0.3 5.9e-83 279.3 0.3 1.1 1 0 0 1 1 1 1 Amidase ThrE PF06738.12 KZN91596.1 - 1e-67 228.0 20.8 4e-62 209.7 5.5 2.9 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KZN91596.1 - 4.1e-13 49.6 8.2 4.1e-13 49.6 8.2 3.0 3 1 1 4 4 4 1 Threonine/Serine exporter, ThrE Pectate_lyase_3 PF12708.7 KZN91597.1 - 8.5e-60 202.2 13.0 1.1e-49 169.2 3.5 2.8 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KZN91597.1 - 0.0048 16.6 1.1 0.011 15.4 0.0 2.2 2 0 0 2 2 2 1 N terminal extension of bacteriophage endosialidase CMV_1a PF12467.8 KZN91598.1 - 0.68 10.3 4.7 0.93 9.8 4.7 1.3 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family MIP PF00230.20 KZN91600.1 - 4.2e-45 154.2 8.7 5.5e-45 153.8 8.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein NAD_binding_1 PF00175.21 KZN91601.1 - 2.9e-13 50.4 0.0 5.2e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 KZN91601.1 - 3.6e-08 33.9 0.0 1.2e-07 32.3 0.0 1.9 2 0 0 2 2 2 1 Globin NAD_binding_6 PF08030.12 KZN91601.1 - 1.9e-05 24.8 0.0 9.6e-05 22.5 0.0 2.1 2 1 1 3 3 3 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 KZN91601.1 - 5.7e-05 23.4 0.0 0.00011 22.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Guanylate_kin PF00625.21 KZN91601.1 - 0.02 14.6 0.1 0.06 13.0 0.0 1.7 1 1 1 2 2 2 0 Guanylate kinase Protoglobin PF11563.8 KZN91601.1 - 0.021 14.7 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Protoglobin Dabb PF07876.12 KZN91601.1 - 0.094 13.3 0.0 0.21 12.2 0.0 1.5 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain DUF4754 PF15946.5 KZN91601.1 - 0.24 11.7 0.5 0.71 10.2 0.2 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4754) NmrA PF05368.13 KZN91602.1 - 6.2e-19 68.5 0.0 7.7e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KZN91602.1 - 1.2e-12 48.2 0.0 1.7e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KZN91602.1 - 0.0055 15.7 0.0 0.0083 15.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 KZN91602.1 - 0.061 13.6 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain HLH PF00010.26 KZN91604.1 - 7.8e-10 38.6 0.0 1.3e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HALZ PF02183.18 KZN91604.1 - 0.042 14.1 0.9 0.081 13.2 0.9 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper AA_permease_2 PF13520.6 KZN91605.1 - 2.4e-61 207.9 50.3 2.9e-61 207.6 50.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN91605.1 - 1.7e-20 73.1 39.8 2.3e-20 72.7 39.8 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1182 PF06681.13 KZN91605.1 - 3.4 7.2 11.7 0.18 11.3 1.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1182) Pro-kuma_activ PF09286.11 KZN91606.1 - 9e-38 129.8 0.2 4e-37 127.7 0.1 2.0 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KZN91606.1 - 8.8e-12 44.9 0.0 2.1e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Subtilase family adh_short PF00106.25 KZN91607.1 - 4.1e-13 49.2 0.0 3.4e-10 39.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KZN91607.1 - 0.008 15.8 0.0 0.082 12.4 0.0 2.1 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN91607.1 - 0.013 15.4 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 KR domain Alpha_GJ PF03229.13 KZN91608.1 - 0.022 15.3 16.2 0.15 12.7 7.8 2.2 2 0 0 2 2 2 0 Alphavirus glycoprotein J DUF3533 PF12051.8 KZN91608.1 - 0.04 12.8 0.3 0.048 12.6 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) FANCI_S1-cap PF14674.6 KZN91608.1 - 0.19 11.8 0.0 0.31 11.2 0.0 1.3 1 0 0 1 1 1 0 FANCI solenoid 1 cap Sugar_tr PF00083.24 KZN91609.1 - 1.1e-110 370.6 25.6 1.4e-110 370.2 25.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN91609.1 - 3.3e-28 98.6 38.8 6.1e-20 71.5 14.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 KZN91610.1 - 1.9e-21 76.6 0.0 1.3e-20 73.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN91610.1 - 3.1e-07 30.0 0.4 4.4e-06 26.2 0.4 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KZN91610.1 - 0.0044 16.7 0.1 0.0077 15.8 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Acetyltransf_1 PF00583.25 KZN91611.1 - 4.3e-06 26.9 0.0 7.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Sugar_tr PF00083.24 KZN91612.1 - 2.2e-39 135.6 20.7 6.1e-28 97.9 7.2 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KZN91612.1 - 5.1e-29 101.3 23.2 5.1e-29 101.3 23.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3533 PF12051.8 KZN91613.1 - 6.9e-127 423.5 10.2 8e-127 423.3 10.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF1746 PF08508.10 KZN91613.1 - 0.019 15.3 1.5 0.23 11.8 0.9 2.4 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1746) DUF202 PF02656.15 KZN91613.1 - 0.076 13.5 0.0 0.076 13.5 0.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF202) PQ-loop PF04193.14 KZN91614.1 - 8.8e-08 31.8 0.9 0.00062 19.5 0.1 3.1 2 0 0 2 2 2 2 PQ loop repeat Transmemb_17 PF09799.9 KZN91614.1 - 0.062 13.9 3.4 0.12 13.0 3.4 1.5 1 0 0 1 1 1 0 Predicted membrane protein SLATT_1 PF18181.1 KZN91614.1 - 0.13 12.2 0.2 0.23 11.4 0.1 1.5 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 Peptidase_U4 PF03419.13 KZN91614.1 - 1.3 8.3 9.5 1 8.6 6.3 1.9 1 1 1 2 2 2 0 Sporulation factor SpoIIGA ECH_1 PF00378.20 KZN91615.1 - 3.2e-42 144.6 0.0 4e-42 144.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KZN91615.1 - 1.2e-28 100.6 0.1 3.9e-26 92.4 0.0 2.0 1 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase RAC_head PF16717.5 KZN91616.1 - 2.5e-31 108.6 2.1 2.5e-31 108.6 2.1 3.2 2 1 1 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 KZN91616.1 - 3.6e-16 59.0 0.6 3.6e-16 59.0 0.6 2.2 2 0 0 2 2 2 1 DnaJ domain CemA PF03040.14 KZN91616.1 - 2.4 8.0 4.3 3.8 7.4 4.3 1.3 1 0 0 1 1 1 0 CemA family AAA_23 PF13476.6 KZN91616.1 - 3.7 8.0 16.9 0.76 10.2 12.7 1.8 2 0 0 2 2 2 0 AAA domain V_ATPase_I PF01496.19 KZN91616.1 - 6.4 4.6 11.4 0.075 11.0 4.0 1.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Complex1_LYR PF05347.15 KZN91617.1 - 3.4e-05 23.8 0.1 6.2e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) RRM_1 PF00076.22 KZN91618.1 - 8.3e-08 31.9 0.0 1.4e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KZN91618.1 - 0.0048 16.9 0.0 0.008 16.2 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Sterol_MT_C PF08498.10 KZN91619.1 - 8.8e-27 93.2 0.1 2e-26 92.1 0.1 1.6 2 0 0 2 2 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KZN91619.1 - 1.3e-21 77.0 0.0 2.8e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN91619.1 - 1.3e-19 70.7 0.0 2.8e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN91619.1 - 4.8e-18 65.4 0.0 7.2e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN91619.1 - 4.8e-12 46.0 0.0 7.8e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KZN91619.1 - 1.2e-10 41.1 0.0 1.8e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KZN91619.1 - 1.8e-10 40.6 0.0 2.9e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KZN91619.1 - 2.1e-09 38.0 0.0 4.4e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KZN91619.1 - 6.6e-05 22.4 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_29 PF03141.16 KZN91619.1 - 0.0001 21.0 0.0 0.00014 20.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_15 PF09445.10 KZN91619.1 - 0.00047 19.8 0.0 0.00077 19.1 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.19 KZN91619.1 - 0.0012 18.6 0.1 0.0027 17.5 0.1 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 KZN91619.1 - 0.0021 17.7 0.0 0.0034 17.0 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 KZN91619.1 - 0.0047 16.5 0.0 0.0081 15.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 KZN91619.1 - 0.0086 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 KZN91619.1 - 0.046 13.7 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 KZN91619.1 - 0.051 12.9 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain TehB PF03848.14 KZN91619.1 - 0.061 12.7 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB DRE2_N PF16803.5 KZN91619.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus Ank_2 PF12796.7 KZN91620.1 - 2.5e-43 146.6 1.6 3.4e-12 46.8 0.0 7.0 5 3 1 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN91620.1 - 9.2e-28 96.3 11.4 0.00019 21.9 0.0 10.3 7 3 2 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 KZN91620.1 - 5.7e-27 92.9 7.1 0.0001 22.6 0.0 9.9 8 1 1 9 9 9 7 Ankyrin repeat Ank_3 PF13606.6 KZN91620.1 - 2.8e-26 88.7 5.9 0.00098 19.4 0.1 11.8 12 1 0 12 12 12 7 Ankyrin repeat Ank_5 PF13857.6 KZN91620.1 - 5.2e-23 80.8 9.8 1.9e-05 24.9 0.0 11.2 10 2 3 13 13 13 4 Ankyrin repeats (many copies) Phosphoesterase PF04185.14 KZN91621.1 - 7.6e-35 120.7 0.8 2.7e-34 118.9 0.8 1.8 1 1 0 1 1 1 1 Phosphoesterase family HIF-1a_CTAD PF08778.10 KZN91621.1 - 0.068 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 HIF-1 alpha C terminal transactivation domain Sugar_tr PF00083.24 KZN91622.1 - 6.8e-113 377.9 25.7 7.9e-113 377.7 25.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN91622.1 - 1.7e-17 63.4 40.0 6.6e-11 41.7 15.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Rx_N PF18052.1 KZN91622.1 - 0.16 12.2 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 Rx N-terminal domain MFS_1 PF07690.16 KZN91623.1 - 1.5e-44 152.4 23.1 1.5e-44 152.4 23.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN91623.1 - 1.2e-14 54.0 0.8 1.2e-14 54.0 0.8 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KZN91623.1 - 2e-06 26.6 1.4 3.3e-06 25.8 1.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TRIQK PF15168.6 KZN91623.1 - 0.12 12.3 0.2 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family Fungal_trans_2 PF11951.8 KZN91624.1 - 9.6e-41 139.9 0.9 1.2e-40 139.5 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN91624.1 - 3e-07 30.5 10.1 5.5e-07 29.6 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 KZN91625.1 - 1.7e-55 188.2 0.2 1.9e-55 188.0 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN91625.1 - 1.5e-40 138.8 0.1 1.8e-40 138.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN91625.1 - 8.7e-10 38.8 0.5 1.2e-09 38.3 0.5 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KZN91625.1 - 0.00085 19.2 0.1 0.0016 18.4 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KZN91625.1 - 0.0053 16.1 0.6 0.013 14.8 0.6 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ChuX_HutX PF06228.13 KZN91625.1 - 0.008 16.0 0.0 0.45 10.3 0.0 2.3 1 1 1 2 2 2 1 Haem utilisation ChuX/HutX Polysacc_synt_2 PF02719.15 KZN91625.1 - 0.04 13.0 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 KZN91625.1 - 0.046 13.2 0.1 0.082 12.3 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Aldedh PF00171.22 KZN91626.1 - 8.2e-132 440.0 0.0 9.2e-132 439.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KZN91626.1 - 0.0012 18.4 0.4 0.0035 16.8 0.4 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Phage_HK97_TLTM PF06120.11 KZN91626.1 - 0.0043 16.3 0.0 0.0082 15.4 0.0 1.4 1 0 0 1 1 1 1 Tail length tape measure protein LuxC PF05893.14 KZN91626.1 - 0.079 12.0 0.3 1.3 8.0 0.0 2.4 2 1 1 3 3 3 0 Acyl-CoA reductase (LuxC) Caskin-tail PF16632.5 KZN91626.1 - 0.1 13.0 0.1 0.25 11.8 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of Caskin DnaB_bind PF10410.9 KZN91626.1 - 0.13 12.5 1.9 0.41 10.9 0.3 2.4 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase Cor1 PF04803.12 KZN91626.1 - 0.23 11.7 0.0 0.42 10.8 0.0 1.4 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region GATase PF00117.28 KZN91627.1 - 4.1e-08 33.2 0.0 5.2e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 KZN91627.1 - 2.2e-05 24.2 0.0 2.5e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 KZN91627.1 - 6.8e-05 22.7 0.0 8.5e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_C26 PF07722.13 KZN91627.1 - 7.1e-05 22.7 0.0 0.00025 20.9 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.19 KZN91627.1 - 0.061 13.2 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Gln-synt_C PF00120.24 KZN91628.1 - 7e-78 262.0 0.0 9e-78 261.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Cation_efflux PF01545.21 KZN91629.1 - 1.7e-13 50.7 9.4 2.4e-13 50.3 9.4 1.1 1 0 0 1 1 1 1 Cation efflux family Cyclase PF04199.13 KZN91631.1 - 1.3e-09 38.4 0.0 3.1e-09 37.2 0.0 1.5 1 1 1 2 2 2 1 Putative cyclase DUF5490 PF17593.2 KZN91631.1 - 0.088 12.8 0.6 0.23 11.5 0.0 2.0 3 0 0 3 3 3 0 Family of unknown function (DUF5490) RHD3 PF05879.12 KZN91632.1 - 0 1055.4 0.0 0 1055.1 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KZN91632.1 - 1.1e-06 28.1 0.1 1.8e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 KZN91632.1 - 7.1e-06 26.2 0.0 1.5e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KZN91632.1 - 0.00077 19.5 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KZN91632.1 - 0.0013 19.0 0.0 0.0037 17.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Phi_1 PF04674.12 KZN91632.1 - 0.096 12.0 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region Zn_clus PF00172.18 KZN91633.1 - 3.7e-06 27.0 12.8 9.4e-06 25.7 12.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN91633.1 - 0.0032 16.6 0.0 0.0067 15.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain GTP_EFTU PF00009.27 KZN91635.1 - 9.4e-58 195.0 0.1 1.3e-57 194.5 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KZN91635.1 - 1.9e-20 73.2 0.0 3.5e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KZN91635.1 - 5.3e-18 65.2 1.5 1.5e-17 63.8 1.5 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KZN91635.1 - 8.4e-06 25.8 0.1 1.8e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KZN91635.1 - 0.0021 18.0 0.1 0.0075 16.2 0.1 1.8 1 1 1 2 2 2 1 RsgA GTPase cobW PF02492.19 KZN91635.1 - 0.044 13.4 0.2 0.22 11.1 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KZN91635.1 - 0.055 13.2 0.1 8.4 6.1 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GDA1_CD39 PF01150.17 KZN91636.1 - 1.2e-100 337.1 0.0 1.6e-100 336.7 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF4598 PF15370.6 KZN91637.1 - 3.4e-33 114.4 16.3 6.2e-33 113.6 4.9 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4598) Macoilin PF09726.9 KZN91637.1 - 0.32 9.5 6.0 0.43 9.1 6.0 1.1 1 0 0 1 1 1 0 Macoilin family BSP_II PF05432.11 KZN91637.1 - 5.5 6.6 22.9 39 3.8 22.8 1.9 1 1 0 1 1 1 0 Bone sialoprotein II (BSP-II) COMPASS-Shg1 PF05205.12 KZN91638.1 - 1.5e-26 93.1 0.0 1.5e-26 93.1 0.0 2.2 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 zf-rbx1 PF12678.7 KZN91640.1 - 1.4e-08 34.9 2.5 3.9e-08 33.5 2.5 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KZN91640.1 - 6.7e-08 32.7 7.0 1.4e-07 31.7 2.4 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KZN91640.1 - 1.4e-06 28.0 0.9 2.5e-06 27.2 0.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KZN91640.1 - 3.4e-06 26.9 1.0 1e-05 25.4 1.0 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KZN91640.1 - 4.1e-06 26.5 7.6 6.7e-06 25.9 2.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KZN91640.1 - 0.00016 21.3 1.2 0.00085 18.9 0.6 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 KZN91640.1 - 0.00026 20.8 1.4 0.00026 20.8 1.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KZN91640.1 - 0.00029 20.7 1.3 0.00029 20.7 1.3 1.9 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KZN91640.1 - 0.0026 17.5 12.0 0.012 15.3 0.3 3.6 4 0 0 4 4 4 2 RING-like zinc finger zf-RING_UBOX PF13445.6 KZN91640.1 - 0.0069 16.4 3.5 0.0069 16.4 3.5 3.6 2 1 1 3 3 3 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KZN91640.1 - 0.0097 15.9 1.1 0.023 14.8 1.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2921 PF11145.8 KZN91640.1 - 0.048 11.5 0.6 0.073 10.9 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) RINGv PF12906.7 KZN91640.1 - 2.5 8.3 5.4 0.56 10.4 1.6 1.8 2 0 0 2 2 2 0 RING-variant domain PQ-loop PF04193.14 KZN91640.1 - 4.4 7.2 10.3 0.46 10.3 0.3 2.9 3 0 0 3 3 2 0 PQ loop repeat FANCL_C PF11793.8 KZN91640.1 - 5.3 7.3 6.0 3.9 7.7 3.0 2.2 2 1 0 2 2 2 0 FANCL C-terminal domain GCV_H PF01597.19 KZN91641.1 - 6.4e-36 122.9 1.8 8.3e-36 122.6 1.8 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Ribosomal_S6 PF01250.17 KZN91642.1 - 1.6e-21 76.3 0.0 2.1e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 4HBT_3 PF13622.6 KZN91643.1 - 1.1e-29 104.5 0.3 2.2e-29 103.5 0.3 1.5 1 1 0 1 1 1 1 Thioesterase-like superfamily DUF4082 PF13313.6 KZN91643.1 - 0.007 16.4 0.1 0.015 15.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4082) PIG-Y PF15159.6 KZN91644.1 - 1.7e-22 80.1 8.2 2.5e-22 79.6 8.2 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF1218 PF06749.12 KZN91644.1 - 0.031 14.8 1.9 4.4 7.9 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) DUF2956 PF11169.8 KZN91644.1 - 6 7.1 6.0 1.9 8.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) RRM_1 PF00076.22 KZN91645.1 - 1.5e-61 204.2 0.0 7.1e-21 73.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KZN91645.1 - 7.2e-11 41.8 0.0 0.0011 18.8 0.0 3.9 3 1 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KZN91645.1 - 1.4e-08 34.4 0.0 0.00063 19.3 0.0 3.3 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KZN91645.1 - 0.00012 22.2 0.1 0.36 11.0 0.0 3.2 3 1 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KZN91645.1 - 0.0006 19.8 0.0 0.44 10.6 0.0 3.3 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.10 KZN91645.1 - 0.0016 18.5 0.0 2.6 8.2 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) SET_assoc PF11767.8 KZN91645.1 - 0.002 17.7 0.0 1.5 8.5 0.0 2.5 2 0 0 2 2 2 2 Histone lysine methyltransferase SET associated RRM_8 PF11835.8 KZN91645.1 - 0.0082 16.3 0.0 1.7 8.9 0.0 2.5 2 0 0 2 2 2 1 RRM-like domain HALZ PF02183.18 KZN91646.1 - 0.57 10.5 2.0 0.66 10.2 0.2 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper Arrestin_C PF02752.22 KZN91647.1 - 7.1e-20 71.8 0.0 5.3e-19 69.0 0.0 2.3 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KZN91647.1 - 6.5e-08 32.8 0.0 0.00076 19.6 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KZN91647.1 - 0.0027 17.5 0.0 0.079 12.7 0.0 2.4 2 0 0 2 2 2 1 Arrestin_N terminal like Acetyltransf_10 PF13673.7 KZN91648.1 - 8.2e-11 41.9 0.0 1.9e-10 40.7 0.0 1.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KZN91648.1 - 1.3e-09 38.3 0.0 2.2e-09 37.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KZN91648.1 - 3e-08 34.0 0.0 4.5e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KZN91648.1 - 0.00019 21.5 0.3 0.084 13.0 0.0 3.0 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KZN91648.1 - 0.0014 18.5 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KZN91648.1 - 0.069 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.7 KZN91648.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Chs7 PF12271.8 KZN91649.1 - 8.8e-124 412.5 14.8 1e-123 412.3 14.8 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF3382 PF11862.8 KZN91649.1 - 0.02 15.2 8.0 0.028 14.7 4.5 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF3382) DUF2873 PF11395.8 KZN91649.1 - 8.7 6.3 8.4 5.7 6.9 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2873) Abhydrolase_6 PF12697.7 KZN91650.1 - 5.2e-05 24.0 1.8 7.9e-05 23.4 1.8 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 KZN91650.1 - 0.00016 21.3 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KZN91650.1 - 0.0011 18.8 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 KZN91650.1 - 0.0047 16.2 0.0 0.0083 15.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LCAT PF02450.15 KZN91650.1 - 0.039 13.1 0.0 0.064 12.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase GATase_4 PF13230.6 KZN91651.1 - 4.4e-12 45.5 0.0 5e-11 42.0 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 KZN91651.1 - 7.6e-08 32.6 0.0 1.3e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Dynamin_N PF00350.23 KZN91652.1 - 4.1e-45 153.9 0.0 7.2e-45 153.1 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KZN91652.1 - 4.3e-14 52.4 0.0 3.6e-11 42.8 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 KZN91652.1 - 5.2e-06 26.5 0.1 0.00035 20.6 0.0 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KZN91652.1 - 0.028 14.8 0.7 0.25 11.7 0.0 2.7 3 1 0 3 3 3 0 AAA ATPase domain Se-cys_synth_N PF12390.8 KZN91652.1 - 0.054 13.7 0.0 0.2 11.9 0.0 2.0 1 0 0 1 1 1 0 Selenocysteine synthase N terminal AAA_15 PF13175.6 KZN91652.1 - 0.065 12.9 0.4 0.24 11.1 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 KZN91652.1 - 0.068 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Roc PF08477.13 KZN91652.1 - 0.18 12.0 0.0 0.67 10.2 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Pyr_redox_2 PF07992.14 KZN91653.1 - 7e-51 173.2 0.0 9e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KZN91653.1 - 6.3e-10 39.5 0.0 4.1e-09 36.9 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KZN91653.1 - 0.0003 20.2 0.0 0.16 11.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase TALPID3 PF15324.6 KZN91653.1 - 0.18 9.5 0.4 0.25 9.0 0.4 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Cyclin PF08613.11 KZN91654.1 - 1.2e-15 58.2 0.1 2e-15 57.6 0.1 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KZN91654.1 - 0.00059 19.6 0.1 0.00093 18.9 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ribosomal_L27A PF00828.19 KZN91655.1 - 1.6e-29 103.2 1.4 2.2e-29 102.7 1.4 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Pkinase PF00069.25 KZN91656.1 - 2e-47 161.8 0.0 2.6e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN91656.1 - 1.3e-26 93.4 0.0 1.5e-20 73.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KZN91656.1 - 0.047 12.5 0.0 0.1 11.3 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase SH3_1 PF00018.28 KZN91657.1 - 1.5e-06 27.7 0.0 3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KZN91657.1 - 0.0023 17.8 0.0 0.0045 16.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_16 PF18348.1 KZN91657.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain Rick_17kDa_Anti PF05433.15 KZN91658.1 - 3.6e-05 23.5 2.9 5.4e-05 23.0 2.9 1.2 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 KZN91658.1 - 0.00088 19.2 0.5 0.0014 18.6 0.5 1.3 1 0 0 1 1 1 1 Glycine zipper TraT PF05818.12 KZN91658.1 - 0.028 14.1 0.3 0.043 13.5 0.3 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF533 PF04391.12 KZN91658.1 - 0.081 12.5 0.1 0.17 11.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF533) HTH_Tnp_Tc5 PF03221.16 KZN91659.1 - 9.5e-07 28.8 0.0 2.2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DHR10 PF18595.1 KZN91659.1 - 0.046 13.8 1.5 0.11 12.5 1.5 1.7 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain HTH_psq PF05225.16 KZN91659.1 - 0.092 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 helix-turn-helix, Psq domain BLOC1_2 PF10046.9 KZN91659.1 - 0.18 12.1 1.2 0.37 11.1 0.1 1.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APH PF01636.23 KZN91660.1 - 4.3e-10 39.9 0.0 6e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KZN91660.1 - 8.5e-08 31.8 0.1 2.5e-07 30.3 0.0 1.6 2 0 0 2 2 2 1 Ecdysteroid kinase Choline_kinase PF01633.20 KZN91660.1 - 0.00011 21.8 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 KZN91660.1 - 0.029 13.2 0.1 0.041 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Aegerolysin PF06355.13 KZN91661.1 - 1e-38 132.4 0.3 1.2e-38 132.1 0.3 1.0 1 0 0 1 1 1 1 Aegerolysin HMG-CoA_red PF00368.18 KZN91664.1 - 7.6e-54 183.1 9.8 3.6e-41 141.4 3.1 3.0 1 1 1 2 2 2 2 Hydroxymethylglutaryl-coenzyme A reductase CBM_4_9 PF02018.17 KZN91665.1 - 0.011 15.9 0.0 0.03 14.6 0.0 1.7 1 0 0 1 1 1 0 Carbohydrate binding domain Cyclin PF08613.11 KZN91666.1 - 4.6e-13 49.9 0.0 6.7e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KZN91666.1 - 6.3e-05 22.7 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain TT_ORF2 PF02957.15 KZN91666.1 - 0.97 10.4 8.3 0.19 12.7 1.8 2.7 3 0 0 3 3 3 0 TT viral ORF2 His_Phos_1 PF00300.22 KZN91667.1 - 7.3e-30 104.1 0.6 1.8e-29 102.8 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) P5-ATPase PF12409.8 KZN91667.1 - 0.015 15.4 1.1 0.1 12.7 0.0 2.4 2 0 0 2 2 2 0 P5-type ATPase cation transporter Dor1 PF04124.12 KZN91668.1 - 5.1e-57 193.1 0.9 6.7e-46 156.5 2.7 2.4 2 0 0 2 2 2 2 Dor1-like family Vps51 PF08700.11 KZN91668.1 - 9.8e-05 22.4 0.4 0.00028 20.9 0.4 1.9 1 0 0 1 1 1 1 Vps51/Vps67 Acetyltransf_3 PF13302.7 KZN91669.1 - 3.2e-09 37.6 0.0 1.2e-08 35.8 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Pkinase PF00069.25 KZN91670.1 - 9.9e-15 54.6 0.0 1.8e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KZN91670.1 - 4.1e-07 29.6 0.0 6e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KZN91670.1 - 8.5e-06 25.2 0.0 1.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KZN91670.1 - 1.2e-05 25.4 0.1 1.5e-05 25.0 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN91670.1 - 0.00036 20.2 0.0 0.00064 19.4 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KZN91670.1 - 0.0042 16.7 0.0 0.0096 15.5 0.0 1.5 1 0 0 1 1 1 1 RIO1 family PhoD PF09423.10 KZN91671.1 - 1.7e-102 343.0 0.3 2.1e-102 342.7 0.3 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 KZN91671.1 - 6.1e-35 119.6 0.0 1.5e-34 118.4 0.0 1.7 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 KZN91671.1 - 5.2e-06 26.9 0.4 1.4e-05 25.6 0.4 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain TNT PF14021.6 KZN91672.1 - 9.3e-31 106.2 0.0 1.6e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 Tuberculosis necrotizing toxin DC_STAMP PF07782.13 KZN91673.1 - 0.034 14.0 0.0 0.034 14.0 0.0 1.1 1 0 0 1 1 1 0 DC-STAMP-like protein FeoB_associated PF12669.7 KZN91673.1 - 0.054 13.9 0.6 0.095 13.1 0.6 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Wzy_C PF04932.15 KZN91673.1 - 0.055 13.1 0.0 0.061 13.0 0.0 1.1 1 0 0 1 1 1 0 O-Antigen ligase Phosphoesterase PF04185.14 KZN91675.1 - 8.5e-46 156.8 2.7 1.4e-45 156.0 2.7 1.3 1 1 0 1 1 1 1 Phosphoesterase family VIT1 PF01988.19 KZN91676.1 - 1.5e-61 208.0 1.6 1.8e-61 207.8 1.6 1.1 1 0 0 1 1 1 1 VIT family 7TMR-DISM_7TM PF07695.11 KZN91676.1 - 0.0041 17.1 1.9 0.0059 16.5 1.9 1.1 1 0 0 1 1 1 1 7TM diverse intracellular signalling Abhydrolase_9_N PF15420.6 KZN91676.1 - 0.034 14.1 0.3 0.066 13.2 0.3 1.5 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus FA_hydroxylase PF04116.13 KZN91676.1 - 0.095 13.0 0.3 0.15 12.4 0.3 1.3 1 0 0 1 1 1 0 Fatty acid hydroxylase superfamily SLATT_fungal PF18142.1 KZN91676.1 - 0.18 11.8 0.2 0.18 11.8 0.2 1.8 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain PAP2_3 PF14378.6 KZN91678.1 - 1.8e-24 86.5 13.2 1.8e-24 86.5 13.2 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 KZN91678.1 - 1.3e-11 44.4 2.2 3.2e-11 43.1 2.2 1.7 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 KZN91678.1 - 2.3 8.8 8.8 0.61 10.7 4.3 2.4 2 0 0 2 2 2 0 PAP2 superfamily C-terminal LCAT PF02450.15 KZN91679.1 - 6.9e-108 361.3 0.0 8.3e-108 361.0 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase BAAT_C PF08840.11 KZN91679.1 - 0.044 13.7 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Lipase_2 PF01674.18 KZN91679.1 - 0.074 12.6 0.1 0.18 11.3 0.1 1.6 2 0 0 2 2 2 0 Lipase (class 2) DUF900 PF05990.12 KZN91679.1 - 0.17 11.4 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Acetyltransf_1 PF00583.25 KZN91680.1 - 7.4e-18 64.9 0.0 1.3e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KZN91680.1 - 2.2e-11 43.8 0.0 3.1e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KZN91680.1 - 1.7e-10 40.7 0.0 2.9e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KZN91680.1 - 2.3e-10 40.7 0.0 4.1e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KZN91680.1 - 1.4e-07 32.2 0.0 1.9e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KZN91680.1 - 3.9e-06 26.6 0.0 5.4e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KZN91680.1 - 3.2e-05 24.0 0.0 7.5e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KZN91680.1 - 0.00073 19.7 0.0 0.00097 19.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KZN91680.1 - 0.0023 18.0 0.0 0.0051 16.9 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 KZN91680.1 - 0.031 14.0 0.1 0.047 13.4 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Pex24p PF06398.11 KZN91682.1 - 1e-05 24.7 10.6 2e-05 23.7 10.6 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Mis14 PF08641.12 KZN91683.1 - 9.8e-28 97.1 3.9 9.8e-28 97.1 3.9 1.7 2 0 0 2 2 2 1 Kinetochore protein Mis14 like LAP1C PF05609.12 KZN91683.1 - 0.31 10.1 6.1 0.13 11.3 4.1 1.4 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) CRAL_TRIO PF00650.20 KZN91684.1 - 4.4e-36 124.0 0.0 5.8e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KZN91684.1 - 3.2e-09 36.8 0.6 7.5e-09 35.6 0.6 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KZN91684.1 - 0.00071 19.7 0.0 0.0013 18.9 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RasGAP PF00616.19 KZN91685.1 - 4.6e-59 199.6 0.4 8.3e-59 198.8 0.1 1.6 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KZN91685.1 - 1.1e-30 106.6 0.4 1.1e-30 106.6 0.4 2.3 2 0 0 2 2 2 1 RasGAP C-terminus MarR PF01047.22 KZN91685.1 - 0.11 12.4 0.2 0.59 10.1 0.1 2.2 2 0 0 2 2 2 0 MarR family CD36 PF01130.21 KZN91685.1 - 0.12 10.8 0.1 0.21 10.1 0.1 1.3 1 0 0 1 1 1 0 CD36 family DNA_pol_A_exo1 PF01612.20 KZN91686.1 - 4.9e-40 137.1 0.1 1.4e-39 135.7 0.1 1.8 2 0 0 2 2 2 1 3'-5' exonuclease PMC2NT PF08066.12 KZN91686.1 - 1.3e-28 99.5 0.4 4.5e-28 97.8 0.4 2.0 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 KZN91686.1 - 1.6e-10 40.8 0.0 3.5e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 HRDC domain DUF778 PF05608.12 KZN91686.1 - 0.38 11.1 1.5 0.83 10.0 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF778) BCIP PF13862.6 KZN91686.1 - 0.85 9.4 4.9 3 7.6 0.0 2.7 3 0 0 3 3 3 0 p21-C-terminal region-binding protein UPF0203 PF05254.12 KZN91687.1 - 1.1e-26 92.8 0.9 1.3e-26 92.6 0.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 KZN91687.1 - 0.00018 21.8 0.5 0.00038 20.7 0.5 1.5 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 KZN91687.1 - 0.0016 18.4 1.4 0.018 15.0 0.1 2.1 1 1 1 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.16 KZN91687.1 - 0.0048 17.1 1.5 1.3 9.2 0.1 2.1 1 1 1 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein DUF5339 PF17274.2 KZN91687.1 - 0.3 11.9 4.0 3.1 8.7 0.4 2.9 2 1 0 2 2 2 0 Family of unknown function (DUF5339) Gpi1 PF05024.15 KZN91688.1 - 3e-78 262.2 8.5 5.6e-78 261.3 8.5 1.5 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) MutS_V PF00488.21 KZN91689.1 - 6.4e-81 270.9 0.1 1.1e-80 270.1 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KZN91689.1 - 6e-38 131.0 0.6 1.5e-37 129.7 0.6 1.7 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 KZN91689.1 - 5.2e-18 65.6 0.3 2.5e-17 63.5 0.0 2.3 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 KZN91689.1 - 6.7e-18 64.8 2.5 9e-18 64.4 1.0 2.1 2 0 0 2 2 2 1 MutS family domain IV MutS_I PF01624.20 KZN91689.1 - 2.6e-15 56.7 0.0 1.9e-14 53.8 0.0 2.2 2 0 0 2 2 2 1 MutS domain I Vip3A_N PF12495.8 KZN91689.1 - 0.038 13.9 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal DUF3168 PF11367.8 KZN91689.1 - 0.13 12.5 0.1 0.52 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3168) SUR7 PF06687.12 KZN91689.1 - 0.13 11.9 0.0 0.78 9.3 0.0 2.1 2 1 0 2 2 2 0 SUR7/PalI family CDT1_C PF16679.5 KZN91690.1 - 3.5e-21 75.5 0.1 6.5e-20 71.4 0.0 2.4 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain Spc7_N PF15402.6 KZN91690.1 - 5.6 5.1 10.6 9.6 4.3 10.6 1.4 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Kdo PF06293.14 KZN91691.1 - 2.2e-07 30.5 0.0 4.3e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KZN91691.1 - 1.4e-06 27.9 0.0 1.7e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KZN91691.1 - 0.00024 20.0 0.0 0.00033 19.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KZN91691.1 - 0.0059 16.6 0.0 0.0086 16.0 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KZN91691.1 - 0.023 14.0 0.0 0.03 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase RIO1 PF01163.22 KZN91691.1 - 0.036 13.6 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 KZN91691.1 - 0.049 13.2 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase PG_binding_4 PF12229.8 KZN91692.1 - 0.018 15.3 1.2 0.031 14.6 0.8 1.5 2 0 0 2 2 2 0 Putative peptidoglycan binding domain ZnuA PF01297.17 KZN91692.1 - 0.032 13.6 0.4 0.045 13.1 0.4 1.2 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic DUF743 PF05332.11 KZN91692.1 - 0.034 14.2 1.9 0.077 13.1 1.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF743) DUF883 PF05957.13 KZN91692.1 - 0.035 14.7 2.0 0.035 14.7 2.0 2.3 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 KZN91692.1 - 0.049 13.5 4.8 0.091 12.6 4.8 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain AIF-MLS PF14962.6 KZN91692.1 - 0.25 11.3 4.5 0.44 10.5 4.5 1.4 1 1 0 1 1 1 0 Mitochondria Localisation Sequence V-ATPase_G_2 PF16999.5 KZN91692.1 - 2.1 8.8 8.8 1.2 9.6 5.8 2.0 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit YtxH PF12732.7 KZN91692.1 - 4.4 7.9 13.9 2e+02 2.6 13.9 2.6 1 1 0 1 1 1 0 YtxH-like protein zf-C2H2 PF00096.26 KZN91693.1 - 2.1e-05 24.7 13.5 0.0056 17.1 2.3 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KZN91693.1 - 0.00027 21.2 3.8 0.00027 21.2 3.8 2.4 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KZN91693.1 - 0.0011 19.6 11.9 0.071 14.0 2.9 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KZN91693.1 - 0.03 14.6 1.0 0.08 13.3 1.0 1.7 1 0 0 1 1 1 0 C2H2-type zinc ribbon TylF PF05711.11 KZN91693.1 - 0.033 13.5 0.0 0.33 10.2 0.0 2.0 2 0 0 2 2 2 0 Macrocin-O-methyltransferase (TylF) zf-H2C2_5 PF13909.6 KZN91693.1 - 1.4 8.7 5.6 2.4 8.0 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain COG5 PF10392.9 KZN91696.1 - 2e-40 138.0 0.5 2e-40 138.0 0.5 2.1 2 0 0 2 2 2 1 Golgi transport complex subunit 5 RTBV_P12 PF06361.11 KZN91696.1 - 0.11 12.9 0.1 0.36 11.2 0.1 1.9 2 0 0 2 2 2 0 Rice tungro bacilliform virus P12 protein Aldolase_II PF00596.21 KZN91697.1 - 4.8e-48 163.6 0.1 6.3e-48 163.2 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF1318 PF07027.12 KZN91697.1 - 0.13 12.7 0.0 0.53 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1318) SYS1 PF09801.9 KZN91698.1 - 1.2e-54 184.4 7.0 1.4e-54 184.2 7.0 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Jagunal PF07086.12 KZN91698.1 - 0.052 13.6 0.9 0.052 13.6 0.9 1.8 2 0 0 2 2 2 0 Jagunal, ER re-organisation during oogenesis DUF4199 PF13858.6 KZN91698.1 - 1.7 9.0 7.3 8.1 6.8 5.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) YwiC PF14256.6 KZN91698.1 - 6.6 7.1 11.9 1.9 8.8 8.3 1.7 1 1 1 2 2 2 0 YwiC-like protein COX6B PF02297.17 KZN91699.1 - 3.1e-23 81.8 4.0 4e-23 81.4 4.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 KZN91699.1 - 0.015 15.6 1.2 0.03 14.6 1.2 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 RRM_1 PF00076.22 KZN91700.1 - 1.9e-08 34.0 0.0 3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KZN91700.1 - 0.00057 19.5 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U3_assoc_6 PF08640.11 KZN91701.1 - 3.2e-29 100.8 0.8 3.2e-29 100.8 0.8 2.1 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 KZN91701.1 - 2.4e-05 24.8 1.3 0.064 14.1 0.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat Suf PF05843.14 KZN91701.1 - 0.0058 16.6 0.9 0.76 9.7 0.0 2.7 3 1 0 3 3 3 2 Suppressor of forked protein (Suf) Frag1 PF10277.9 KZN91702.1 - 2.7e-42 144.8 9.2 2.7e-42 144.8 9.2 2.7 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family Lactamase_B_6 PF16661.5 KZN91704.1 - 2.1e-65 219.8 0.0 4.6e-65 218.7 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KZN91704.1 - 7.1e-47 159.7 0.0 1.7e-46 158.5 0.0 1.7 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KZN91704.1 - 1e-15 58.0 0.0 6.5e-15 55.4 0.0 2.3 2 1 1 3 3 3 1 Beta-Casp domain RMMBL PF07521.12 KZN91704.1 - 6e-12 45.3 0.0 1.5e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 KZN91704.1 - 0.013 15.5 0.1 0.035 14.1 0.1 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily AA_permease_2 PF13520.6 KZN91705.1 - 1e-58 199.2 43.1 1.4e-58 198.7 43.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN91705.1 - 2.7e-18 65.8 37.7 3.6e-18 65.4 37.7 1.0 1 0 0 1 1 1 1 Amino acid permease Sec23_trunk PF04811.15 KZN91706.1 - 6.9e-54 183.0 0.0 2e-53 181.5 0.0 1.7 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KZN91706.1 - 2.1e-25 88.5 0.0 4.1e-25 87.6 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KZN91706.1 - 4.1e-17 62.7 0.0 8e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KZN91706.1 - 8.9e-16 57.7 5.2 1.7e-15 56.7 5.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KZN91706.1 - 3.3e-08 33.3 0.0 7.2e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat DUF1678 PF07913.11 KZN91706.1 - 0.12 12.1 0.1 0.23 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) Gti1_Pac2 PF09729.9 KZN91707.1 - 2.5e-44 151.5 7.3 2.3e-37 128.8 0.1 3.1 2 1 1 3 3 3 2 Gti1/Pac2 family tRNA-synt_2 PF00152.20 KZN91708.1 - 1.6e-67 227.9 0.0 5.8e-67 226.0 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KZN91708.1 - 7.6e-06 25.8 0.0 1.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RRM_1 PF00076.22 KZN91709.1 - 8.9e-12 44.7 0.0 2.1e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAM184 PF15665.5 KZN91709.1 - 0.034 13.9 0.3 0.18 11.6 0.1 2.1 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B DHR10 PF18595.1 KZN91709.1 - 0.078 13.0 1.4 0.23 11.5 1.4 1.8 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Gp-FAR-1 PF05823.12 KZN91709.1 - 0.15 12.4 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF148 PF02520.17 KZN91709.1 - 0.27 11.4 3.5 6.2 7.0 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF148 DUF3763 PF12592.8 KZN91709.1 - 0.68 10.0 3.6 1.9 8.6 3.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3763) MOZ_SAS PF01853.18 KZN91710.1 - 7e-62 208.3 0.0 1e-61 207.7 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KZN91710.1 - 9.5e-17 60.4 0.2 1.6e-16 59.6 0.2 1.4 1 0 0 1 1 1 1 MYST family zinc finger domain Cpn60_TCP1 PF00118.24 KZN91711.1 - 4.7e-163 543.3 0.3 5.3e-163 543.2 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nop PF01798.18 KZN91712.1 - 1.8e-89 299.2 0.1 1.8e-89 299.2 0.1 1.7 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KZN91712.1 - 4.6e-19 68.6 0.1 4.6e-19 68.6 0.1 2.5 2 0 0 2 2 2 1 NOP5NT (NUC127) domain Rrn6 PF10214.9 KZN91712.1 - 0.0028 16.2 1.5 0.0033 16.0 1.5 1.2 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor YL1 PF05764.13 KZN91712.1 - 0.63 10.1 26.6 0.96 9.5 26.6 1.3 1 0 0 1 1 1 0 YL1 nuclear protein RP-C_C PF11800.8 KZN91712.1 - 5.8 7.0 11.3 8.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Replication protein C C-terminal region CobT PF06213.12 KZN91712.1 - 8.5 5.7 24.9 1.9 7.8 20.7 2.0 3 0 0 3 3 3 0 Cobalamin biosynthesis protein CobT DUF3767 PF12597.8 KZN91714.1 - 3.8e-32 110.1 0.0 5.3e-32 109.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) TMA7 PF09072.10 KZN91714.1 - 0.47 11.3 4.8 0.91 10.4 4.8 1.4 1 0 0 1 1 1 0 Translation machinery associated TMA7 DUF1744 PF08490.12 KZN91715.1 - 3.3e-150 500.1 0.0 4.7e-150 499.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KZN91715.1 - 5e-85 285.6 3.1 5.3e-85 285.5 0.9 2.1 3 0 0 3 3 3 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KZN91715.1 - 2.1e-14 53.1 0.0 9.9e-11 41.0 0.0 3.6 3 1 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KZN91715.1 - 9.3e-07 28.7 0.2 3e-06 27.1 0.2 1.8 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KZN91715.1 - 0.00015 21.8 0.0 0.00066 19.7 0.0 2.2 1 0 0 1 1 1 1 RNase_H superfamily zf-MIZ PF02891.20 KZN91715.1 - 0.11 12.3 1.9 3.1 7.6 0.3 2.8 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-CHY PF05495.12 KZN91715.1 - 0.25 11.9 2.1 0.9 10.1 2.1 1.9 1 0 0 1 1 1 0 CHY zinc finger Pkinase PF00069.25 KZN91716.1 - 1.9e-73 247.1 0.0 2.4e-73 246.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN91716.1 - 2e-30 106.0 0.0 2.5e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KZN91716.1 - 2e-07 30.6 0.0 3.2e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KZN91716.1 - 6.8e-05 21.8 0.0 0.00011 21.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KZN91716.1 - 0.00013 21.4 0.0 0.00024 20.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KZN91716.1 - 0.0004 20.4 0.1 0.00068 19.6 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family AMMECR1 PF01871.17 KZN91717.1 - 7e-40 136.4 0.0 1.2e-39 135.7 0.0 1.6 1 1 0 1 1 1 1 AMMECR1 Apt1 PF10351.9 KZN91717.1 - 0.0071 15.2 6.3 0.0074 15.2 6.3 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain PAP1 PF08601.10 KZN91717.1 - 0.081 12.6 13.0 0.11 12.2 13.0 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 RP-C_C PF11800.8 KZN91717.1 - 0.084 13.0 4.3 0.12 12.5 4.3 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region PBP1_TM PF14812.6 KZN91717.1 - 0.098 13.0 1.8 0.17 12.3 1.8 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RHINO PF15319.6 KZN91717.1 - 0.14 12.2 6.0 0.19 11.7 6.0 1.1 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein Sigma70_ner PF04546.13 KZN91717.1 - 0.27 11.1 5.6 0.42 10.5 5.6 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region SPX PF03105.19 KZN91717.1 - 0.36 10.7 14.2 0.48 10.3 14.2 1.1 1 0 0 1 1 1 0 SPX domain CPSF100_C PF13299.6 KZN91717.1 - 0.48 10.6 4.1 0.79 9.9 4.1 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Macoilin PF09726.9 KZN91717.1 - 0.95 7.9 11.0 1.2 7.6 11.0 1.1 1 0 0 1 1 1 0 Macoilin family PI3K_1B_p101 PF10486.9 KZN91717.1 - 1.5 6.5 10.8 1.9 6.1 10.8 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CDK2AP PF09806.9 KZN91717.1 - 1.5 8.8 10.1 2.8 8.0 10.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein PBP_sp32 PF07222.12 KZN91717.1 - 6.2 6.2 15.1 0.07 12.6 7.2 1.7 2 0 0 2 2 2 0 Proacrosin binding protein sp32 HNH_2 PF13391.6 KZN91718.1 - 5e-15 55.4 0.0 4.5e-14 52.3 0.0 2.1 2 0 0 2 2 2 1 HNH endonuclease SHMT PF00464.19 KZN91719.1 - 5.7e-208 690.4 0.0 6.5e-208 690.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KZN91719.1 - 3.9e-07 29.6 0.0 9.2e-07 28.3 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KZN91719.1 - 0.0017 17.4 0.0 0.0027 16.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KZN91719.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KZN91719.1 - 0.073 11.6 0.0 0.13 10.7 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KZN91719.1 - 0.098 11.9 0.2 0.34 10.2 0.2 1.8 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Med9 PF07544.13 KZN91720.1 - 2.1e-17 63.0 0.0 5e-17 61.8 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.8 KZN91720.1 - 0.01 16.1 1.1 0.016 15.5 1.1 1.5 1 1 0 1 1 1 0 Subunit 21 of Mediator complex Spc29 PF17082.5 KZN91720.1 - 0.021 14.7 0.1 0.029 14.2 0.1 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 DUF2730 PF10805.8 KZN91720.1 - 0.03 14.4 0.0 0.04 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF3782 PF12644.7 KZN91720.1 - 0.077 13.1 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) GP41 PF00517.17 KZN91720.1 - 0.092 12.6 0.1 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 Retroviral envelope protein iPGM_N PF06415.13 KZN91721.1 - 4e-75 252.0 0.0 5.8e-75 251.4 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 KZN91721.1 - 1.3e-69 234.3 0.0 1.5e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 KZN91721.1 - 3e-07 30.4 0.0 4.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KZN91721.1 - 8.9e-05 22.0 0.0 0.00017 21.1 0.0 1.6 1 0 0 1 1 1 1 Sulfatase Alk_phosphatase PF00245.20 KZN91721.1 - 0.057 12.4 0.1 0.17 10.8 0.0 1.7 2 0 0 2 2 2 0 Alkaline phosphatase Prefoldin_2 PF01920.20 KZN91722.1 - 2.2e-22 79.0 13.2 2.9e-22 78.6 13.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit Spc24 PF08286.11 KZN91722.1 - 0.00079 19.6 13.0 0.061 13.6 3.1 2.1 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 DUF3727 PF12527.8 KZN91722.1 - 0.013 15.7 3.1 0.61 10.3 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3727) APG6_N PF17675.1 KZN91722.1 - 0.022 15.3 5.5 0.022 15.3 5.5 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region XhlA PF10779.9 KZN91722.1 - 0.11 12.7 0.4 0.11 12.7 0.4 1.8 2 0 0 2 2 2 0 Haemolysin XhlA THOC7 PF05615.13 KZN91722.1 - 0.16 12.3 12.7 0.31 11.3 12.7 1.4 1 1 0 1 1 1 0 Tho complex subunit 7 Prefoldin PF02996.17 KZN91722.1 - 0.28 11.1 12.6 0.72 9.8 12.6 1.7 1 1 0 1 1 1 0 Prefoldin subunit Chibby PF14645.6 KZN91722.1 - 0.38 11.2 7.1 3 8.3 0.1 2.9 1 1 2 3 3 3 0 Chibby family HalX PF08663.10 KZN91722.1 - 0.56 10.6 8.7 12 6.3 0.2 3.2 2 2 0 2 2 2 0 HalX domain SpecificRecomb PF10136.9 KZN91722.1 - 0.59 8.4 6.8 0.65 8.2 6.8 1.0 1 0 0 1 1 1 0 Site-specific recombinase GAS PF13851.6 KZN91722.1 - 0.69 9.2 16.2 1.9 7.8 5.5 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding PHM7_cyt PF14703.6 KZN91722.1 - 0.76 10.0 7.5 1.8 8.8 7.5 1.7 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter FlaC_arch PF05377.11 KZN91722.1 - 0.92 10.0 10.8 1.2 9.6 2.5 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DHR10 PF18595.1 KZN91722.1 - 1 9.4 19.6 0.4 10.8 5.8 2.1 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF5082 PF16888.5 KZN91722.1 - 1.2 9.4 13.4 4.7 7.5 13.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) CorA PF01544.18 KZN91722.1 - 1.3 8.3 5.9 1 8.6 2.6 1.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DivIC PF04977.15 KZN91722.1 - 1.4 8.8 18.5 0.82 9.5 1.5 3.1 2 1 1 3 3 3 0 Septum formation initiator COG2 PF06148.11 KZN91722.1 - 1.5 8.9 8.8 1 9.5 1.8 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Osmo_CC PF08946.10 KZN91722.1 - 1.9 8.8 9.3 0.16 12.2 2.6 2.4 2 1 0 2 2 2 0 Osmosensory transporter coiled coil JIP_LZII PF16471.5 KZN91722.1 - 2 8.7 9.1 6.5 7.0 1.6 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Rx_N PF18052.1 KZN91722.1 - 2.1 8.6 9.3 4 7.8 2.3 2.3 1 1 1 2 2 2 0 Rx N-terminal domain HIP1_clath_bdg PF16515.5 KZN91722.1 - 2.5 8.7 18.4 2.2 8.9 6.5 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 bZIP_1 PF00170.21 KZN91722.1 - 2.8 8.1 11.4 7.9 6.7 1.3 2.9 2 1 0 2 2 2 0 bZIP transcription factor Spc7 PF08317.11 KZN91722.1 - 5.6 5.8 18.2 17 4.2 18.2 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 KZN91722.1 - 5.8 7.6 12.6 8.6 7.1 2.4 2.1 1 1 1 2 2 2 0 Initiation control protein YabA Fib_alpha PF08702.10 KZN91722.1 - 7.9 6.7 10.2 16 5.7 8.9 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 KZN91722.1 - 9.5 6.3 20.1 4.8 7.2 5.0 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus AAA PF00004.29 KZN91723.1 - 5.1e-42 143.4 0.0 8.6e-42 142.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KZN91723.1 - 3e-30 104.0 0.1 1e-29 102.3 0.1 2.0 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KZN91723.1 - 2e-23 82.2 2.0 2e-23 82.2 2.0 1.9 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain RuvB_N PF05496.12 KZN91723.1 - 9.2e-06 25.5 0.0 2.2e-05 24.2 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KZN91723.1 - 1.5e-05 25.4 0.0 0.00018 22.0 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_lid_3 PF17862.1 KZN91723.1 - 1.7e-05 24.5 0.0 7.8e-05 22.4 0.0 2.1 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 KZN91723.1 - 2.7e-05 24.2 0.0 0.00012 22.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KZN91723.1 - 4.7e-05 23.7 0.0 0.011 16.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase DUF815 PF05673.13 KZN91723.1 - 4.8e-05 22.6 0.0 0.0011 18.2 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 KZN91723.1 - 7.4e-05 22.6 0.0 0.00016 21.4 0.0 1.6 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KZN91723.1 - 0.00011 22.5 0.1 0.019 15.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 KZN91723.1 - 0.00014 21.2 0.0 0.00024 20.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 KZN91723.1 - 0.00019 21.6 0.0 0.0073 16.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 KZN91723.1 - 0.00034 20.7 0.0 0.00068 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KZN91723.1 - 0.00045 20.8 0.0 0.0019 18.8 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 KZN91723.1 - 0.0015 18.3 0.0 0.011 15.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KZN91723.1 - 0.0016 18.6 0.0 0.0037 17.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KZN91723.1 - 0.0075 15.9 0.2 0.65 9.5 0.1 2.9 2 1 0 3 3 3 1 AAA domain AAA_17 PF13207.6 KZN91723.1 - 0.01 16.3 0.1 0.036 14.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KZN91723.1 - 0.014 15.0 0.0 0.089 12.3 0.0 2.3 2 1 0 2 2 2 0 P-loop containing dynein motor region USP8_dimer PF08969.11 KZN91723.1 - 0.017 15.3 3.1 0.036 14.3 3.1 1.6 1 0 0 1 1 1 0 USP8 dimerisation domain Mg_chelatase PF01078.21 KZN91723.1 - 0.022 14.1 0.1 0.07 12.5 0.1 1.9 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI Torsin PF06309.11 KZN91723.1 - 0.046 13.8 0.0 0.094 12.8 0.0 1.5 1 0 0 1 1 1 0 Torsin ATPase_2 PF01637.18 KZN91723.1 - 0.064 13.2 1.2 1.3 8.9 0.0 2.8 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 KZN91723.1 - 0.064 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 KZN91723.1 - 0.065 12.7 0.1 0.16 11.4 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 KZN91723.1 - 0.088 12.7 0.0 0.67 9.9 0.0 2.1 1 1 1 2 2 2 0 NACHT domain AFG1_ATPase PF03969.16 KZN91723.1 - 0.2 10.5 0.0 0.31 9.9 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase Cytidylate_kin PF02224.18 KZN91723.1 - 0.23 11.2 1.2 0.51 10.0 0.0 2.1 2 1 1 3 3 3 0 Cytidylate kinase Cnn_1N PF07989.11 KZN91724.1 - 1.4e-22 79.6 5.0 1.4e-22 79.6 5.0 14.8 7 4 8 15 15 15 3 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 KZN91724.1 - 1.6e-22 79.9 1.8 1.6e-22 79.9 1.8 4.0 4 1 0 4 4 4 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Pox_A_type_inc PF04508.12 KZN91724.1 - 2.4 8.1 0.0 2.4 8.1 0.0 9.9 10 0 0 10 10 10 0 Viral A-type inclusion protein repeat SGT1 PF07093.11 KZN91725.1 - 3.1e-94 316.5 14.8 9.9e-87 291.7 0.0 2.1 1 1 1 2 2 2 2 SGT1 protein Folliculin PF11704.8 KZN91726.1 - 4e-52 176.8 0.0 6.9e-52 176.0 0.0 1.4 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport CSN8_PSD8_EIF3K PF10075.9 KZN91727.1 - 7.3e-50 168.7 0.0 9.2e-50 168.4 0.0 1.1 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Pkinase PF00069.25 KZN91728.1 - 4.5e-34 118.0 0.0 1.2e-33 116.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN91728.1 - 2.7e-13 49.8 0.0 1.4e-11 44.2 0.0 3.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KZN91728.1 - 0.01 15.8 0.1 0.047 13.6 0.1 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KZN91728.1 - 0.12 11.4 0.1 0.21 10.5 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 KZN91728.1 - 0.14 11.7 1.3 0.3 10.7 0.1 2.0 3 0 0 3 3 3 0 RIO1 family PDCD2_C PF04194.13 KZN91729.1 - 6.5e-41 140.3 0.0 3.6e-40 137.9 0.0 2.0 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain A2L_zn_ribbon PF08792.10 KZN91729.1 - 0.1 12.4 0.2 7.5 6.4 0.1 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain Prenylcys_lyase PF07156.14 KZN91730.1 - 7.2e-96 321.5 0.0 9.4e-96 321.1 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 KZN91730.1 - 7.9e-13 48.4 0.0 1.6e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KZN91730.1 - 1.1e-09 38.2 0.0 6.6e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 KZN91730.1 - 3.8e-06 26.7 0.3 0.00079 19.1 0.3 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KZN91730.1 - 0.0087 16.1 0.3 0.032 14.2 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KZN91730.1 - 0.01 15.1 0.0 0.079 12.2 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_3 PF07859.13 KZN91730.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold HI0933_like PF03486.14 KZN91730.1 - 0.12 11.1 0.1 0.86 8.2 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein GATase PF00117.28 KZN91731.1 - 1.2e-40 139.4 0.0 2e-40 138.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 KZN91731.1 - 3.6e-36 123.1 0.0 8.5e-36 121.9 0.0 1.7 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.17 KZN91731.1 - 2.1e-09 36.9 0.1 7.4e-06 25.2 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 KZN91731.1 - 3.4e-05 23.7 0.2 0.00012 21.9 0.2 1.9 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 KZN91731.1 - 0.00034 19.5 0.3 0.00081 18.3 0.1 1.6 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 KZN91731.1 - 0.0024 17.4 0.0 0.016 14.7 0.0 2.0 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 KZN91731.1 - 0.0032 17.1 0.0 0.0059 16.2 0.0 1.4 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 KZN91731.1 - 0.0033 17.5 0.0 0.0055 16.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.19 KZN91731.1 - 0.0037 16.6 0.1 0.0052 16.1 0.1 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase CLP1_P PF16575.5 KZN91732.1 - 2.7e-26 92.5 0.0 4.8e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 KZN91732.1 - 0.0063 16.9 0.4 2.8 8.3 0.0 2.8 3 0 0 3 3 3 2 AAA ATPase domain RNA_helicase PF00910.22 KZN91732.1 - 0.046 14.1 0.0 0.091 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 KZN91732.1 - 0.057 13.1 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KZN91732.1 - 0.082 13.4 0.0 0.24 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KZN91732.1 - 0.091 12.9 4.2 0.1 12.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.20 KZN91732.1 - 0.12 11.5 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Adeno_IVa2 PF02456.15 KZN91732.1 - 0.25 10.1 0.0 0.38 9.5 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein RNA_polI_A34 PF08208.11 KZN91733.1 - 1.6e-42 146.0 17.0 1.6e-42 146.0 17.0 2.1 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 GRAM PF02893.20 KZN91734.1 - 6.5e-36 122.7 2.2 1.1e-23 83.2 0.0 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 KZN91734.1 - 3.3e-26 92.0 0.0 7.3e-26 90.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 KZN91734.1 - 5.5e-16 59.0 0.0 1.3e-14 54.5 0.0 2.9 3 0 0 3 3 3 1 PH domain PH_11 PF15413.6 KZN91734.1 - 8.9e-06 26.1 1.3 0.00025 21.4 1.3 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KZN91734.1 - 0.00024 21.2 0.0 0.0005 20.1 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KZN91734.1 - 0.00032 20.9 0.0 0.00079 19.7 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain UDPGT PF00201.18 KZN91734.1 - 0.028 13.2 0.0 0.047 12.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase DUF4288 PF14119.6 KZN91734.1 - 0.033 14.6 0.5 0.17 12.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) PH_6 PF15406.6 KZN91734.1 - 0.14 12.4 0.0 0.61 10.4 0.0 2.2 1 0 0 1 1 1 0 Pleckstrin homology domain Prefoldin PF02996.17 KZN91735.1 - 4.5e-29 100.8 0.1 8e-29 100.0 0.1 1.4 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KZN91735.1 - 6.9e-05 22.8 0.9 0.00038 20.4 0.0 2.2 2 1 0 2 2 2 1 Prefoldin subunit DUF4201 PF13870.6 KZN91735.1 - 0.0027 17.4 1.5 0.18 11.6 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) Syntaxin-6_N PF09177.11 KZN91735.1 - 0.0057 17.2 3.2 1.3 9.6 0.2 2.2 1 1 1 2 2 2 2 Syntaxin 6, N-terminal End3 PF12761.7 KZN91735.1 - 0.033 14.4 0.8 0.12 12.5 0.1 2.1 1 1 2 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 DUF4795 PF16043.5 KZN91735.1 - 0.044 13.4 0.6 2.9 7.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) FlaC_arch PF05377.11 KZN91735.1 - 0.062 13.7 3.6 1.2 9.6 0.1 3.0 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Vma12 PF11712.8 KZN91736.1 - 1.2e-36 125.9 0.0 1.6e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Amidohydro_1 PF01979.20 KZN91737.1 - 1.3e-28 100.3 0.0 6e-28 98.2 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KZN91737.1 - 3.8e-13 49.7 0.1 8.1e-08 32.1 0.0 2.8 2 1 0 3 3 3 2 Amidohydrolase family Ribosomal_S14 PF00253.21 KZN91739.1 - 2.6e-23 81.5 1.2 1.6e-21 75.8 0.2 2.2 2 0 0 2 2 2 2 Ribosomal protein S14p/S29e ATP-synt_J PF04911.12 KZN91740.1 - 3.5e-24 84.1 1.1 3.9e-24 84.0 1.1 1.0 1 0 0 1 1 1 1 ATP synthase j chain DASH_Spc19 PF08287.11 KZN91741.1 - 6e-52 175.7 5.4 8.1e-52 175.3 5.4 1.2 1 0 0 1 1 1 1 Spc19 Mur_ligase_M PF08245.12 KZN91741.1 - 0.0022 18.0 0.0 0.0022 18.0 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain COG5 PF10392.9 KZN91741.1 - 1.6 8.9 7.8 9.3 6.4 0.2 3.0 2 1 1 3 3 3 0 Golgi transport complex subunit 5 Rsm22 PF09243.10 KZN91742.1 - 5.6e-32 111.1 0.1 4.4e-30 104.9 0.0 2.5 2 1 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 PBP1_TM PF14812.6 KZN91742.1 - 3.9 7.9 8.3 15 6.1 8.3 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Rogdi_lz PF10259.9 KZN91743.1 - 2.3e-85 286.3 0.1 2.6e-85 286.1 0.1 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein SUR7 PF06687.12 KZN91744.1 - 7.1e-41 140.2 11.3 8.3e-41 140.0 11.3 1.0 1 0 0 1 1 1 1 SUR7/PalI family Clc-like PF07062.12 KZN91744.1 - 0.0041 16.6 0.3 0.0041 16.6 0.3 1.5 2 0 0 2 2 2 1 Clc-like Amastin PF07344.11 KZN91744.1 - 0.014 15.2 6.8 0.014 15.2 6.8 1.7 2 1 1 3 3 3 0 Amastin surface glycoprotein DUF373 PF04123.13 KZN91744.1 - 1.8 8.0 4.5 0.68 9.3 0.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF373) HSP70 PF00012.20 KZN91745.1 - 7.6e-81 272.1 1.0 7.6e-81 272.1 1.0 1.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KZN91745.1 - 3.6e-09 35.9 0.2 5.4e-09 35.3 0.2 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Peripla_BP_6 PF13458.6 KZN91745.1 - 0.001 18.8 0.1 0.0018 18.0 0.1 1.4 1 0 0 1 1 1 1 Periplasmic binding protein KH_6 PF15985.5 KZN91746.1 - 5.5e-17 61.9 0.2 1.4e-16 60.5 0.1 1.8 2 0 0 2 2 2 1 KH domain Rrp40_N PF18311.1 KZN91746.1 - 6e-10 38.9 0.6 1.7e-09 37.5 0.6 1.8 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain Myb_DNA-binding PF00249.31 KZN91747.1 - 5.7e-19 68.0 5.5 1.1e-08 35.1 0.2 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KZN91747.1 - 1.1e-17 64.0 3.7 5.1e-12 45.9 1.2 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 KZN91747.1 - 0.014 15.5 1.7 0.71 10.1 0.0 2.6 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Glyco_transf_24 PF18404.1 KZN91748.1 - 4.9e-147 488.5 0.7 7.7e-147 487.8 0.7 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KZN91748.1 - 4.8e-66 223.3 0.0 6.4e-64 216.4 0.0 2.5 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KZN91748.1 - 2.1e-48 164.7 0.0 4.4e-48 163.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 KZN91748.1 - 3.7e-47 161.0 0.7 8.5e-46 156.5 1.4 2.2 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 KZN91748.1 - 7.5e-44 148.9 1.8 5.4e-43 146.2 0.0 3.0 3 0 0 3 3 3 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KZN91748.1 - 5.2e-42 142.4 0.0 1.1e-41 141.4 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 KZN91748.1 - 0.0007 19.2 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Rpp20 PF12328.8 KZN91750.1 - 2.7e-49 166.6 18.2 6.3e-49 165.5 18.2 1.6 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 KZN91750.1 - 2.8e-20 71.9 1.1 4.8e-20 71.2 1.1 1.4 1 0 0 1 1 1 1 Alba ATG2_CAD PF13329.6 KZN91750.1 - 0.021 14.6 0.2 0.038 13.7 0.2 1.5 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif Presenilin PF01080.17 KZN91750.1 - 3.3 6.4 7.2 4.2 6.0 7.2 1.1 1 0 0 1 1 1 0 Presenilin FHA PF00498.26 KZN91751.1 - 3.7e-17 62.4 0.0 8.2e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KZN91751.1 - 0.00037 20.8 0.0 0.0009 19.5 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain YhfZ_C PF14503.6 KZN91751.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 YhfZ C-terminal domain EMP24_GP25L PF01105.24 KZN91751.1 - 2 8.3 6.0 0.41 10.6 0.7 2.4 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD DUF812 PF05667.11 KZN91751.1 - 2.5 6.9 24.3 0.019 13.9 15.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DUF2408 PF10303.9 KZN91751.1 - 3.1 8.3 10.5 0.18 12.4 2.9 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) GrpE PF01025.19 KZN91751.1 - 3.8 7.2 12.0 1.3 8.7 4.9 2.8 3 0 0 3 3 3 0 GrpE DUF2203 PF09969.9 KZN91751.1 - 4.6 8.0 11.6 7.1 7.4 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Spectrin PF00435.21 KZN91751.1 - 6 7.4 11.2 17 6.0 0.3 2.8 3 0 0 3 3 3 0 Spectrin repeat Romo1 PF10247.9 KZN91752.1 - 3.9e-28 97.6 16.2 5e-28 97.3 16.2 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 KZN91752.1 - 0.00028 21.2 2.6 0.00034 21.0 2.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TMEM141 PF15110.6 KZN91752.1 - 2.1 9.0 4.5 3.1 8.5 0.8 2.1 1 1 1 2 2 2 0 TMEM141 protein family ABC_tran PF00005.27 KZN91753.1 - 7.8e-35 120.4 0.0 2.3e-34 118.9 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 KZN91753.1 - 6.6e-22 78.4 5.5 1.2e-21 77.5 5.5 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KZN91753.1 - 5.5e-08 32.5 0.0 1.2e-05 24.9 0.0 2.5 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 KZN91753.1 - 0.002 17.4 1.0 0.034 13.4 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 KZN91753.1 - 0.0021 18.5 0.1 0.0073 16.7 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain AAA_15 PF13175.6 KZN91753.1 - 0.0029 17.4 0.0 0.0052 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 KZN91753.1 - 0.0062 17.1 0.9 0.0097 16.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KZN91753.1 - 0.0099 16.0 0.6 0.11 12.5 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 KZN91753.1 - 0.012 15.9 0.1 0.035 14.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KZN91753.1 - 0.016 15.6 0.0 0.16 12.4 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KZN91753.1 - 0.018 14.2 0.1 0.045 12.9 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.6 KZN91753.1 - 0.02 14.9 0.1 1.4 8.9 0.0 3.3 3 1 0 3 3 3 0 AAA domain AAA_21 PF13304.6 KZN91753.1 - 0.028 14.2 0.0 0.079 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KZN91753.1 - 0.035 13.9 1.1 0.062 13.1 0.1 1.9 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KZN91753.1 - 0.042 14.0 0.0 1 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KZN91753.1 - 0.065 13.8 0.1 0.21 12.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 KZN91753.1 - 0.098 12.4 0.0 0.32 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 KZN91753.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit NACHT PF05729.12 KZN91753.1 - 0.28 11.1 1.9 2.4 8.0 0.2 2.8 3 0 0 3 3 3 0 NACHT domain MGC-24 PF05283.11 KZN91754.1 - 1.4 9.4 8.6 1.9 8.9 8.6 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin NUDE_C PF04880.13 KZN91754.1 - 3.5 8.1 9.5 4.2 7.8 9.5 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region MAP65_ASE1 PF03999.12 KZN91754.1 - 4.3 5.9 8.6 4.9 5.7 8.6 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) LRR_8 PF13855.6 KZN91755.1 - 1.3e-10 40.8 9.5 1.1e-08 34.7 7.3 2.7 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KZN91755.1 - 2.3e-07 31.0 8.3 2.2e-06 27.9 3.2 3.3 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KZN91755.1 - 0.0022 17.5 0.4 0.0036 16.8 0.4 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 KZN91755.1 - 0.14 12.8 7.7 14 6.7 0.2 5.2 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 KZN91755.1 - 0.33 11.1 1.3 40 4.6 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich repeat adh_short PF00106.25 KZN91756.1 - 6.3e-41 140.0 0.1 9e-41 139.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN91756.1 - 5e-29 101.5 0.0 6.9e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN91756.1 - 8e-14 52.0 0.2 1.1e-13 51.4 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KZN91756.1 - 5.6e-05 22.7 0.1 0.00065 19.2 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KZN91756.1 - 0.00087 18.5 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KZN91756.1 - 0.066 13.1 0.3 0.14 12.1 0.3 1.6 1 1 0 1 1 1 0 NAD(P)H-binding zf-RING_2 PF13639.6 KZN91757.1 - 5.6e-13 49.0 5.6 9e-13 48.3 5.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KZN91757.1 - 5.3e-09 35.7 2.3 5.3e-09 35.7 2.3 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KZN91757.1 - 1e-08 34.8 4.3 1.7e-08 34.1 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KZN91757.1 - 1.9e-08 34.5 2.9 3.9e-08 33.4 2.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain PA PF02225.22 KZN91757.1 - 5.6e-08 32.7 0.0 1.5e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 PA domain zf-C3HC4 PF00097.25 KZN91757.1 - 6.4e-08 32.4 3.8 1e-07 31.7 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KZN91757.1 - 1.9e-07 30.9 3.0 3.1e-07 30.3 3.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KZN91757.1 - 6.2e-06 26.1 2.0 5e-05 23.2 2.5 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KZN91757.1 - 1.1e-05 25.2 3.4 1.6e-05 24.6 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KZN91757.1 - 0.0012 18.8 1.0 0.0022 18.0 1.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KZN91757.1 - 0.0026 17.6 2.6 0.0045 16.8 2.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 FANCL_C PF11793.8 KZN91757.1 - 0.088 13.0 2.4 0.23 11.6 2.4 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KZN91757.1 - 0.1 12.2 2.6 0.19 11.4 2.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KZN91757.1 - 0.24 11.6 2.7 0.57 10.4 2.7 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 KZN91757.1 - 0.49 10.6 4.3 0.95 9.6 4.3 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 KZN91757.1 - 1.1 9.1 3.6 2 8.3 3.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 KZN91757.1 - 1.5 9.2 3.7 3.1 8.2 3.7 1.5 1 0 0 1 1 1 0 RING-like domain adh_short PF00106.25 KZN91759.1 - 2.7e-21 75.9 0.0 3.9e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN91759.1 - 1.1e-13 51.2 0.0 1.5e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN91759.1 - 1.7e-06 28.1 0.0 2.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KZN91759.1 - 0.0017 18.3 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KZN91759.1 - 0.015 14.8 0.1 0.087 12.3 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KZN91759.1 - 0.048 13.1 0.0 0.095 12.1 0.0 1.5 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Raptor_N PF14538.6 KZN91760.1 - 3e-64 215.4 0.0 5.5e-64 214.6 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 KZN91760.1 - 0.00014 22.6 11.0 0.84 10.6 0.1 6.3 5 1 0 5 5 5 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 KZN91760.1 - 0.006 16.6 0.1 6 6.9 0.0 2.7 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Kelch_3 PF13415.6 KZN91761.1 - 1.3e-32 111.4 6.5 3.5e-06 27.1 0.1 6.1 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KZN91761.1 - 8.3e-30 102.5 9.1 3.1e-05 23.9 0.0 6.6 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KZN91761.1 - 7e-28 96.1 5.4 2.4e-05 24.2 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 KZN91761.1 - 4.9e-26 90.1 1.3 3.5e-09 36.1 0.1 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 KZN91761.1 - 9.5e-25 86.0 5.8 6.2e-08 32.7 0.3 6.3 4 1 2 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KZN91761.1 - 7.7e-18 63.7 8.2 1.7e-05 24.6 0.2 6.4 6 0 0 6 6 6 4 Kelch motif DUF5082 PF16888.5 KZN91761.1 - 0.012 15.9 4.4 0.012 15.9 4.4 5.4 5 1 0 5 5 5 0 Domain of unknown function (DUF5082) RAG2 PF03089.14 KZN91761.1 - 0.1 11.5 0.0 1.2 8.0 0.0 2.6 4 0 0 4 4 4 0 Recombination activating protein 2 Pkinase PF00069.25 KZN91762.1 - 7.4e-26 91.1 0.0 9.7e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN91762.1 - 6.8e-14 51.8 0.0 9.7e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KZN91762.1 - 5.1e-09 35.4 0.0 7.2e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KZN91762.1 - 0.00023 21.1 0.0 0.0017 18.3 0.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family bZIP_1 PF00170.21 KZN91763.1 - 2.9e-09 36.9 10.0 5.7e-09 35.9 10.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KZN91763.1 - 7.3e-05 22.8 15.4 9.3e-05 22.4 14.1 1.8 1 1 1 2 2 2 1 Basic region leucine zipper PAP1 PF08601.10 KZN91763.1 - 0.00056 19.7 10.4 0.019 14.7 0.0 2.1 2 0 0 2 2 2 1 Transcription factor PAP1 bZIP_Maf PF03131.17 KZN91763.1 - 0.00087 19.8 8.8 0.0014 19.1 8.8 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor MIS13 PF08202.11 KZN91763.1 - 0.0027 17.1 1.1 0.0036 16.6 1.1 1.1 1 0 0 1 1 1 1 Mis12-Mtw1 protein family V_ATPase_I PF01496.19 KZN91763.1 - 0.015 13.3 2.1 0.019 12.9 2.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SHE3 PF17078.5 KZN91763.1 - 0.026 14.2 4.6 0.037 13.8 4.6 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF5094 PF17015.5 KZN91763.1 - 0.031 14.4 4.3 0.048 13.8 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) TMF_TATA_bd PF12325.8 KZN91763.1 - 0.049 13.8 3.1 0.093 13.0 3.1 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF5595 PF18077.1 KZN91763.1 - 0.057 13.5 2.0 0.1 12.7 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) FlaC_arch PF05377.11 KZN91763.1 - 0.06 13.7 0.1 0.1 13.0 0.1 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) YabA PF06156.13 KZN91763.1 - 0.061 14.0 0.7 0.11 13.1 0.7 1.5 1 0 0 1 1 1 0 Initiation control protein YabA PSI_PsaF PF02507.15 KZN91763.1 - 0.11 12.3 1.4 0.19 11.6 1.4 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III CLZ PF16526.5 KZN91763.1 - 0.12 12.7 2.3 0.23 11.8 2.3 1.5 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DivIC PF04977.15 KZN91763.1 - 0.16 11.7 5.6 0.35 10.7 5.6 1.6 1 0 0 1 1 1 0 Septum formation initiator GvpL_GvpF PF06386.11 KZN91763.1 - 0.18 11.7 5.0 0.32 10.9 5.0 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF NRBF2 PF08961.10 KZN91763.1 - 0.34 10.5 7.0 0.71 9.4 6.8 1.6 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator TSC22 PF01166.18 KZN91763.1 - 0.54 10.6 2.9 8 6.9 3.0 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family UPF0242 PF06785.11 KZN91763.1 - 0.57 10.2 5.0 0.87 9.7 5.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ZapB PF06005.12 KZN91763.1 - 1.5 9.3 9.8 0.12 12.8 4.0 2.1 1 1 1 2 2 2 0 Cell division protein ZapB Phosducin PF02114.16 KZN91764.1 - 3.4e-11 42.6 0.1 4.6e-11 42.2 0.1 1.2 1 0 0 1 1 1 1 Phosducin Adaptin_N PF01602.20 KZN91765.1 - 1.9e-111 373.2 0.2 2.5e-111 372.8 0.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KZN91765.1 - 1.6e-57 193.9 1.6 3.7e-57 192.7 1.6 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KZN91765.1 - 1.8e-34 118.3 0.6 7.4e-34 116.3 0.2 2.4 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KZN91765.1 - 5.5e-18 65.2 0.2 1.9e-11 44.2 0.0 5.5 4 1 2 6 6 6 3 HEAT repeats Cnd1 PF12717.7 KZN91765.1 - 1.1e-08 35.3 6.9 0.0057 16.7 0.1 5.0 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KZN91765.1 - 0.00051 20.1 6.7 0.27 11.6 0.3 5.8 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 KZN91765.1 - 0.0091 16.5 0.7 0.049 14.2 0.2 2.6 2 0 0 2 2 2 1 HEAT-like repeat HEAT_PBS PF03130.16 KZN91765.1 - 0.018 15.7 4.3 14 6.7 0.0 5.3 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat TetR_C_28 PF17937.1 KZN91765.1 - 0.28 11.6 1.8 38 4.8 0.0 3.6 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain tRNA-synt_2 PF00152.20 KZN91766.1 - 5.8e-71 239.1 0.1 7.7e-71 238.7 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KZN91766.1 - 3.4e-06 26.9 0.1 6.5e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Hydrolase_6 PF13344.6 KZN91767.1 - 7.9e-25 86.9 0.0 2e-24 85.6 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KZN91767.1 - 2.6e-17 62.7 0.0 8.3e-17 61.0 0.0 1.9 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KZN91767.1 - 1.1e-06 29.1 0.0 0.064 13.5 0.1 3.7 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KZN91767.1 - 0.0073 16.4 0.0 1.7 8.7 0.0 2.5 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 KZN91767.1 - 0.041 14.3 0.0 4.6 7.6 0.0 2.9 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase F-box-like PF12937.7 KZN91768.1 - 4.1e-06 26.6 0.5 1.1e-05 25.2 0.5 1.7 1 0 0 1 1 1 1 F-box-like NmrA PF05368.13 KZN91769.1 - 1.2e-16 61.0 0.0 2.1e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KZN91769.1 - 6.9e-13 48.9 0.2 1.2e-12 48.1 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KZN91769.1 - 1.1e-07 32.2 0.0 1.8e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KZN91769.1 - 5.2e-05 22.8 0.0 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KZN91769.1 - 0.0019 18.7 0.1 0.0035 17.8 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KZN91769.1 - 0.0022 18.8 0.0 0.0043 17.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ApbA PF02558.16 KZN91769.1 - 0.009 15.7 0.1 0.017 14.8 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DapB_N PF01113.20 KZN91769.1 - 0.011 15.9 0.3 0.034 14.3 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Rossmann-like PF10727.9 KZN91769.1 - 0.024 14.5 0.1 0.054 13.4 0.1 1.6 1 0 0 1 1 1 0 Rossmann-like domain Ldh_1_N PF00056.23 KZN91769.1 - 0.038 14.1 0.6 0.11 12.6 0.5 1.9 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain KR PF08659.10 KZN91769.1 - 0.04 13.8 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 KR domain DUF2391 PF09622.10 KZN91769.1 - 0.1 11.9 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 Putative integral membrane protein (DUF2391) SIP1 PF04938.12 KZN91770.1 - 7e-13 48.8 0.0 1.9e-10 40.8 0.0 2.4 2 0 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) Curto_V2 PF07325.11 KZN91770.1 - 0.094 12.6 0.9 0.13 12.1 0.3 1.5 1 1 0 1 1 1 0 Curtovirus V2 protein DUF1476 PF07345.11 KZN91770.1 - 0.23 11.9 2.6 15 6.0 0.3 2.6 2 1 0 2 2 2 0 ATPase inhibitor subunit zeta Trypan_PARP PF05887.11 KZN91770.1 - 6 6.9 16.6 12 5.9 16.6 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PX PF00787.24 KZN91771.1 - 4.6e-14 52.4 0.0 9.9e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 PX domain BCIP PF13862.6 KZN91771.1 - 0.061 13.1 0.5 0.11 12.2 0.5 1.4 1 0 0 1 1 1 0 p21-C-terminal region-binding protein DGF-1_C PF11040.8 KZN91771.1 - 0.064 13.3 2.0 0.32 11.0 0.0 2.9 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Cyclase PF04199.13 KZN91773.1 - 1.5e-15 57.7 0.1 1.9e-15 57.3 0.1 1.2 1 0 0 1 1 1 1 Putative cyclase Cupin_3 PF05899.12 KZN91773.1 - 0.018 14.7 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Sugar_tr PF00083.24 KZN91774.1 - 3.9e-80 269.9 24.6 4.6e-80 269.7 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN91774.1 - 1.9e-23 83.0 59.0 1.1e-20 73.9 35.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_1 PF00583.25 KZN91775.1 - 4.9e-09 36.4 0.0 7.1e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KZN91775.1 - 0.00026 21.4 0.0 0.00043 20.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Ecotin PF03974.13 KZN91775.1 - 0.00039 20.4 0.1 0.0012 18.9 0.0 1.8 2 1 0 2 2 2 1 Ecotin Acetyltransf_10 PF13673.7 KZN91775.1 - 0.001 19.0 0.1 0.0059 16.5 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain YjbF PF11102.8 KZN91775.1 - 0.022 14.6 1.4 1.2 8.9 0.2 2.3 2 1 0 2 2 2 0 Group 4 capsule polysaccharide lipoprotein gfcB, YjbF Fungal_trans PF04082.18 KZN91776.1 - 2e-09 36.8 0.0 3.7e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PIN_12 PF16289.5 KZN91776.1 - 0.11 13.0 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 PIN domain zf-RING_2 PF13639.6 KZN91777.1 - 5.9e-11 42.5 7.3 1.1e-10 41.7 7.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KZN91777.1 - 1.1e-08 34.6 1.8 1.1e-08 34.6 1.8 1.7 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KZN91777.1 - 1.2e-07 31.4 5.3 2.2e-07 30.6 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KZN91777.1 - 1.5e-07 31.2 4.4 2.4e-07 30.5 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KZN91777.1 - 5.6e-07 29.5 2.6 1e-06 28.6 2.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KZN91777.1 - 2.8e-05 24.0 5.4 4.3e-05 23.4 5.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KZN91777.1 - 0.00013 22.2 9.3 0.00054 20.2 9.3 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 KZN91777.1 - 0.00021 20.9 5.9 0.00021 20.9 5.9 1.9 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KZN91777.1 - 0.00039 20.2 4.9 0.001 18.9 4.9 1.7 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KZN91777.1 - 0.00059 19.8 2.0 0.00088 19.3 2.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KZN91777.1 - 0.0013 18.6 3.6 0.0024 17.7 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS1595 PF12760.7 KZN91777.1 - 0.0087 16.0 3.9 0.02 14.8 0.7 2.2 2 0 0 2 2 2 1 Transposase zinc-ribbon domain RINGv PF12906.7 KZN91777.1 - 0.016 15.3 4.7 0.016 15.3 4.7 2.0 1 1 1 2 2 2 0 RING-variant domain TMEM154 PF15102.6 KZN91777.1 - 0.017 15.0 0.1 0.022 14.7 0.1 1.2 1 0 0 1 1 1 0 TMEM154 protein family Rtf2 PF04641.12 KZN91777.1 - 0.031 13.7 0.1 0.038 13.3 0.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Cad PF03596.13 KZN91777.1 - 0.031 14.2 0.1 0.049 13.5 0.1 1.2 1 0 0 1 1 1 0 Cadmium resistance transporter Mid2 PF04478.12 KZN91777.1 - 0.035 14.0 0.9 0.053 13.3 0.8 1.4 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor Rax2 PF12768.7 KZN91777.1 - 0.06 12.8 0.0 0.082 12.4 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity FANCL_C PF11793.8 KZN91777.1 - 0.067 13.4 7.6 0.39 10.9 7.6 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KZN91777.1 - 0.075 12.8 4.9 0.13 12.1 4.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TMEM51 PF15345.6 KZN91777.1 - 0.095 12.5 0.2 0.11 12.3 0.2 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 zf-RING-like PF08746.11 KZN91777.1 - 0.12 12.7 4.6 0.21 11.9 4.6 1.4 1 0 0 1 1 1 0 RING-like domain MMPL PF03176.15 KZN91777.1 - 0.21 10.5 0.0 0.27 10.1 0.0 1.1 1 0 0 1 1 1 0 MMPL family zf-Nse PF11789.8 KZN91777.1 - 0.51 10.2 2.5 0.81 9.5 2.5 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zf_RING PF16744.5 KZN91777.1 - 2.3 8.4 8.6 11 6.2 7.9 2.1 1 1 0 1 1 1 0 KIAA1045 RING finger zf-C3HC4_4 PF15227.6 KZN91777.1 - 2.7 8.2 6.1 38 4.6 6.5 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Homeodomain PF00046.29 KZN91778.1 - 1.4e-14 53.7 3.1 3e-14 52.6 3.1 1.6 1 0 0 1 1 1 1 Homeodomain Amino_oxidase PF01593.24 KZN91779.1 - 7.2e-53 180.5 0.1 3.7e-52 178.1 0.1 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KZN91779.1 - 4e-16 59.0 0.4 1.2e-15 57.5 0.2 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Prenylcys_lyase PF07156.14 KZN91779.1 - 7.9e-06 25.2 0.1 1.1e-05 24.8 0.1 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase Pyr_redox_2 PF07992.14 KZN91779.1 - 1.1e-05 24.8 0.4 2.1e-05 23.9 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KZN91779.1 - 5.8e-05 22.8 4.1 0.00027 20.6 4.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KZN91779.1 - 6.1e-05 23.5 0.1 0.00014 22.3 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KZN91779.1 - 0.00061 19.8 1.0 0.1 12.6 0.5 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KZN91779.1 - 0.0018 17.1 0.9 0.0022 16.8 0.2 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KZN91779.1 - 0.0026 17.2 0.0 0.0037 16.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KZN91779.1 - 0.0027 16.9 0.2 0.004 16.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KZN91779.1 - 0.0054 16.0 0.3 0.0095 15.2 0.3 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KZN91779.1 - 0.012 14.8 0.4 0.02 14.1 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 KZN91779.1 - 0.026 13.8 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KZN91779.1 - 0.14 12.0 0.5 0.26 11.2 0.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2235 PF09994.9 KZN91781.1 - 1.4e-101 339.7 0.2 2.1e-101 339.1 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) An_peroxidase PF03098.15 KZN91782.1 - 3e-38 131.7 0.0 1.4e-20 73.4 0.0 3.2 1 1 2 3 3 3 3 Animal haem peroxidase p450 PF00067.22 KZN91782.1 - 5.2e-06 25.5 0.1 0.0003 19.7 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 HTH_Tnp_Tc5 PF03221.16 KZN91783.1 - 1.3e-10 41.2 0.0 3.5e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain LMBR1 PF04791.16 KZN91783.1 - 0.36 9.7 0.9 0.35 9.7 0.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein YabA PF06156.13 KZN91783.1 - 3 8.5 6.0 0.41 11.3 1.6 1.8 2 0 0 2 2 2 0 Initiation control protein YabA Hexapep PF00132.24 KZN91784.1 - 5.8e-06 25.8 9.4 0.011 15.4 4.1 4.9 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KZN91784.1 - 0.0087 15.8 0.4 0.0087 15.8 0.4 2.6 3 1 1 4 4 4 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KZN91784.1 - 0.13 11.1 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase Glycos_transf_1 PF00534.20 KZN91785.1 - 1.4e-18 67.0 0.0 2.5e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KZN91785.1 - 1.2e-13 51.7 0.0 2e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KZN91785.1 - 1.7e-05 25.1 0.0 3.9e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Arf PF00025.21 KZN91786.1 - 4.2e-71 238.0 0.1 4.9e-71 237.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KZN91786.1 - 3.5e-16 59.5 0.1 4.8e-16 59.0 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KZN91786.1 - 3.5e-13 49.5 0.0 3.9e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KZN91786.1 - 6.8e-13 48.5 1.3 1.2e-08 34.6 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KZN91786.1 - 5.4e-12 45.5 0.0 6.6e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KZN91786.1 - 4.1e-10 39.4 0.0 4.7e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KZN91786.1 - 7.1e-06 26.1 0.1 1.6e-05 25.0 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KZN91786.1 - 0.0019 17.8 0.0 0.0038 16.8 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KZN91786.1 - 0.0095 15.5 0.4 0.018 14.6 0.2 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B 6PF2K PF01591.18 KZN91786.1 - 0.017 14.4 0.3 0.03 13.6 0.3 1.6 1 1 0 1 1 1 0 6-phosphofructo-2-kinase Hva1_TUDOR PF11160.8 KZN91787.1 - 1e-06 28.8 1.8 9.3e-06 25.7 1.8 1.9 1 1 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain MCM6_C PF18263.1 KZN91788.1 - 0.1 12.8 0.1 0.16 12.2 0.0 1.3 1 1 0 1 1 1 0 MCM6 C-terminal winged-helix domain Meth_synt_2 PF01717.18 KZN91789.1 - 1.9e-09 37.3 0.0 3.3e-06 26.6 0.0 2.6 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KZN91789.1 - 0.024 14.2 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain F-box PF00646.33 KZN91790.1 - 0.27 11.2 3.6 2.4 8.1 0.3 3.2 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 KZN91790.1 - 0.65 9.9 9.4 0.14 12.1 2.6 3.1 3 1 0 3 3 3 0 F-box-like Lys-AminoMut_A PF09043.11 KZN91791.1 - 0.07 11.6 0.0 0.099 11.1 0.0 1.1 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit PHD PF00628.29 KZN91792.1 - 3.6e-10 39.6 7.1 3.6e-10 39.6 7.1 2.4 2 0 0 2 2 2 1 PHD-finger APH PF01636.23 KZN91792.1 - 0.064 13.2 0.1 0.36 10.7 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family RR_TM4-6 PF06459.12 KZN91792.1 - 2.9 7.6 5.9 6.6 6.5 5.9 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2486 PF10667.9 KZN91792.1 - 3.7 7.7 12.1 8.4 6.5 12.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) Ndc1_Nup PF09531.10 KZN91792.1 - 6.6 5.3 5.8 9.9 4.7 5.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TPR_10 PF13374.6 KZN91793.1 - 1.1e-64 212.6 0.6 1.7e-10 40.4 0.0 6.6 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 KZN91793.1 - 1.5e-56 188.6 17.1 5.1e-15 55.5 0.3 5.7 2 1 5 7 7 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 KZN91793.1 - 8.4e-22 75.6 4.2 0.00033 20.5 0.0 7.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_MalT PF17874.1 KZN91793.1 - 1.2e-15 57.8 9.2 8.7e-10 38.5 3.6 2.3 1 1 1 2 2 2 2 MalT-like TPR region TPR_2 PF07719.17 KZN91793.1 - 5.6e-15 54.2 0.1 0.054 13.6 0.0 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KZN91793.1 - 2.3e-13 49.3 0.0 0.24 11.3 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 KZN91793.1 - 3.8e-12 45.9 3.9 1.4 10.0 0.0 7.9 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KZN91793.1 - 1.5e-11 44.6 1.9 0.11 13.0 0.1 6.4 1 1 5 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KZN91793.1 - 3.1e-11 42.6 0.0 1.8 9.0 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KZN91793.1 - 9.3e-11 42.2 2.9 0.032 14.9 0.1 6.2 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 KZN91793.1 - 9.3e-11 41.3 21.7 0.29 11.9 0.0 6.7 8 0 0 8 8 5 5 Tetratricopeptide repeat TPR_6 PF13174.6 KZN91793.1 - 5.7e-07 29.8 0.1 0.85 10.4 0.0 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_5 PF12688.7 KZN91793.1 - 7.1e-07 29.5 3.1 0.034 14.4 0.1 4.4 1 1 3 4 4 4 2 Tetratrico peptide repeat NB-ARC PF00931.22 KZN91793.1 - 3.2e-06 26.5 0.1 0.04 13.1 0.0 2.9 3 0 0 3 3 3 2 NB-ARC domain TPR_17 PF13431.6 KZN91793.1 - 3.2e-06 27.1 0.2 5.7 7.6 0.0 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KZN91793.1 - 0.00083 19.5 0.0 1.2 9.4 0.0 4.0 2 2 3 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 AAA_16 PF13191.6 KZN91793.1 - 0.0028 18.0 2.8 0.014 15.7 0.6 3.1 2 1 0 2 2 2 1 AAA ATPase domain PPR PF01535.20 KZN91793.1 - 0.0035 17.5 2.4 3.7 8.0 0.0 5.1 5 0 0 5 5 5 1 PPR repeat NACHT PF05729.12 KZN91793.1 - 0.013 15.5 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain TPR_11 PF13414.6 KZN91793.1 - 0.058 13.1 1.1 64 3.4 0.0 4.5 5 0 0 5 5 5 0 TPR repeat PPR_1 PF12854.7 KZN91793.1 - 0.062 13.0 2.1 70 3.3 0.0 4.6 5 0 0 5 5 5 0 PPR repeat RPN6_N PF18055.1 KZN91793.1 - 0.07 13.5 1.3 15 5.9 0.1 3.4 2 1 2 5 5 5 0 26S proteasome regulatory subunit RPN6 N-terminal domain Helo_like_N PF17111.5 KZN91794.1 - 7.2e-14 51.7 5.4 9.3e-14 51.3 5.4 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Mis12 PF05859.12 KZN91794.1 - 0.017 15.2 3.7 0.077 13.0 1.0 2.2 2 0 0 2 2 2 0 Mis12 protein CCDC84 PF14968.6 KZN91794.1 - 0.019 14.6 0.6 0.025 14.2 0.6 1.3 1 0 0 1 1 1 0 Coiled coil protein 84 Sigma70_r2 PF04542.14 KZN91795.1 - 0.042 13.6 0.3 1.3 8.9 0.0 2.8 3 0 0 3 3 3 0 Sigma-70 region 2 BRF1 PF07741.13 KZN91795.1 - 1.2 9.6 7.9 2.4 8.5 7.9 1.5 1 0 0 1 1 1 0 Brf1-like TBP-binding domain AMP-binding PF00501.28 KZN91796.1 - 4.7e-76 256.1 0.0 1.1e-75 254.9 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KZN91796.1 - 4.9e-60 202.9 0.0 1.2e-59 201.5 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.25 KZN91796.1 - 2.4e-51 174.0 2.4 4.4e-51 173.1 2.4 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN91796.1 - 2.1e-37 128.9 1.4 3.9e-37 128.0 1.4 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN91796.1 - 3.6e-18 66.1 3.7 6e-15 55.6 2.3 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 KZN91796.1 - 2e-16 60.2 0.0 1.4e-08 34.5 0.0 2.8 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KZN91796.1 - 2.1e-12 47.2 0.0 4.6e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KZN91796.1 - 8.5e-09 34.8 0.1 0.00017 20.7 0.0 3.2 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KZN91796.1 - 2.2e-06 27.0 0.9 0.0001 21.5 0.0 2.6 3 0 0 3 3 3 1 RmlD substrate binding domain DFP PF04127.15 KZN91796.1 - 0.0085 15.9 1.5 0.035 13.9 1.6 2.0 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Polysacc_synt_2 PF02719.15 KZN91796.1 - 0.009 15.2 0.4 5.2 6.1 0.2 3.3 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein ApbA PF02558.16 KZN91796.1 - 0.019 14.6 0.1 0.041 13.5 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GDP_Man_Dehyd PF16363.5 KZN91796.1 - 0.076 12.4 0.0 3 7.2 0.0 2.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KZN91796.1 - 0.21 11.1 1.1 3.3 7.2 1.4 2.6 3 0 0 3 3 3 0 NmrA-like family Sugar_tr PF00083.24 KZN91797.1 - 2e-99 333.5 22.4 2.2e-99 333.3 22.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN91797.1 - 5.1e-26 91.4 52.1 6.7e-25 87.8 35.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 KZN91797.1 - 1.7 9.2 8.1 1.7 9.2 3.6 3.0 3 0 0 3 3 3 0 Phage holin family 2 EMP70 PF02990.16 KZN91797.1 - 2.9 6.4 10.0 7.4 5.1 10.0 1.6 1 0 0 1 1 1 0 Endomembrane protein 70 Fungal_trans PF04082.18 KZN91798.1 - 1.2e-27 96.7 0.0 2e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN91798.1 - 1.1e-10 41.4 12.9 2e-10 40.6 12.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 KZN91798.1 - 0.092 12.9 2.2 0.1 12.8 0.1 2.1 2 0 0 2 2 2 0 Gal4-like dimerisation domain 2OG-FeII_Oxy_3 PF13640.6 KZN91799.1 - 7.4e-13 49.2 0.1 1.1e-12 48.6 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-C2H2 PF00096.26 KZN91800.1 - 2.8e-07 30.6 15.4 3.5e-05 24.0 2.8 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KZN91800.1 - 9.4e-06 25.8 5.7 2.7e-05 24.4 3.3 2.6 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KZN91800.1 - 0.00011 22.7 1.7 0.00011 22.7 1.7 3.0 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KZN91800.1 - 0.00089 19.5 2.8 0.0021 18.3 2.8 1.7 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KZN91800.1 - 0.0032 17.7 1.9 0.0039 17.4 0.7 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KZN91800.1 - 0.0041 17.1 1.3 0.0085 16.1 1.3 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-TRAF PF02176.18 KZN91800.1 - 0.11 13.2 5.0 0.37 11.5 2.4 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger FOXP-CC PF16159.5 KZN91800.1 - 0.49 11.1 7.4 2.1 9.1 0.4 3.2 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2H2_2 PF12756.7 KZN91800.1 - 4.4 7.7 5.7 2.5 8.5 2.6 2.2 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 KZN91800.1 - 7.2 7.0 7.9 14 6.1 0.5 2.4 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Forkhead PF00250.18 KZN91801.1 - 8.2e-36 122.1 1.4 1.4e-35 121.3 1.4 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KZN91801.1 - 9.5e-08 32.3 0.0 2.6e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 FHA domain TENA_THI-4 PF03070.16 KZN91802.1 - 9e-13 48.5 0.0 5.2e-07 29.7 0.0 2.2 2 0 0 2 2 2 2 TENA/THI-4/PQQC family CR6_interact PF10147.9 KZN91803.1 - 0.013 15.2 0.9 0.027 14.2 0.9 1.4 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 PHD PF00628.29 KZN91805.1 - 4.4e-06 26.5 10.3 8.4e-06 25.6 10.3 1.5 1 0 0 1 1 1 1 PHD-finger ING PF12998.7 KZN91805.1 - 6.7e-06 26.6 0.0 1.5e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.6 KZN91805.1 - 0.026 14.8 2.0 0.054 13.8 2.0 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain PH_14 PF17787.1 KZN91805.1 - 0.057 13.3 0.2 0.15 11.9 0.2 1.6 1 0 0 1 1 1 0 PH domain DUF5466 PF17554.2 KZN91806.1 - 0.41 10.9 3.8 0.87 9.8 3.8 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5466) GFO_IDH_MocA PF01408.22 KZN91807.1 - 9.8e-11 42.5 0.1 2.6e-10 41.2 0.1 1.9 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DHDPS PF00701.22 KZN91808.1 - 5.4e-33 113.9 0.0 1.7e-26 92.6 0.0 2.0 2 0 0 2 2 2 2 Dihydrodipicolinate synthetase family His_Phos_1 PF00300.22 KZN91809.1 - 1.6e-19 70.4 0.1 2e-18 66.8 0.1 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Astro_capsid_p PF12226.8 KZN91810.1 - 0.038 13.2 2.8 0.057 12.6 2.8 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop14 PF04147.12 KZN91810.1 - 7.5 4.6 17.5 9.8 4.2 17.5 1.1 1 0 0 1 1 1 0 Nop14-like family ADH_N PF08240.12 KZN91811.1 - 7.1e-26 90.2 4.2 1.2e-25 89.5 4.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN91811.1 - 8.6e-16 58.1 0.0 2e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KZN91811.1 - 0.00045 19.6 0.1 0.00078 18.9 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain WD40 PF00400.32 KZN91812.1 - 2e-28 98.0 11.6 4.7e-05 24.1 1.3 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat F-box-like PF12937.7 KZN91812.1 - 4.7e-09 36.0 0.1 1.1e-08 34.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KZN91812.1 - 0.00014 22.1 0.0 0.19 12.0 0.0 4.5 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KZN91812.1 - 0.0008 19.1 0.0 0.44 10.1 0.0 2.4 1 1 1 2 2 2 2 PQQ-like domain PQQ PF01011.21 KZN91812.1 - 0.0014 18.5 0.0 3 7.9 0.0 3.5 3 0 0 3 3 3 1 PQQ enzyme repeat WD40_like PF17005.5 KZN91812.1 - 0.0034 16.8 0.2 0.021 14.2 0.0 2.1 3 0 0 3 3 3 1 WD40-like domain Nup160 PF11715.8 KZN91812.1 - 0.025 13.3 0.3 3.3 6.3 0.0 2.7 3 0 0 3 3 3 0 Nucleoporin Nup120/160 DUF5046 PF16465.5 KZN91812.1 - 0.027 13.9 0.0 0.3 10.5 0.0 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF5046) EB1 PF03271.17 KZN91813.1 - 8.4e-17 61.1 1.1 1.7e-16 60.2 1.1 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif Herpes_UL6 PF01763.16 KZN91813.1 - 0.014 13.9 0.0 0.019 13.5 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like FTCD_C PF04961.12 KZN91813.1 - 0.027 14.2 0.2 0.04 13.7 0.2 1.2 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Cation_ATPase_C PF00689.21 KZN91814.1 - 2.6e-47 160.9 9.5 6.9e-47 159.5 9.5 1.8 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KZN91814.1 - 1.2e-37 129.2 0.1 1.2e-37 129.2 0.1 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KZN91814.1 - 1.6e-19 69.8 0.0 2.9e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KZN91814.1 - 4.2e-18 66.4 0.4 1.4e-17 64.7 0.4 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KZN91814.1 - 4.6e-08 32.6 0.2 2.6e-07 30.2 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KZN91814.1 - 3.3e-05 23.8 0.0 0.0012 18.7 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase VirB3 PF05101.13 KZN91814.1 - 7.3 6.9 12.0 3.8 7.8 2.6 3.7 3 0 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein P16-Arc PF04699.14 KZN91815.1 - 1.3e-45 155.6 0.0 1.4e-45 155.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Methyltransf_11 PF08241.12 KZN91816.1 - 3.2e-11 43.7 0.0 8.5e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN91816.1 - 1.4e-08 34.7 0.0 2.2e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN91816.1 - 1.2e-07 32.3 0.0 4.1e-07 30.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN91816.1 - 1.1e-06 29.3 0.0 2.2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN91816.1 - 2.3e-05 24.2 0.0 5.5e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KZN91816.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Dynactin_p62 PF05502.13 KZN91817.1 - 2.4e-194 646.6 0.0 2.4e-194 646.6 0.0 1.5 2 0 0 2 2 2 1 Dynactin p62 family Pox_Ag35 PF03286.14 KZN91817.1 - 1 9.1 7.3 2.8 7.7 7.3 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Mu-like_Com PF10122.9 KZN91817.1 - 2.2 7.8 5.5 2.9 7.4 0.8 2.9 2 0 0 2 2 2 0 Mu-like prophage protein Com Trm112p PF03966.16 KZN91817.1 - 5.4 7.7 6.7 21 5.8 0.3 3.3 3 0 0 3 3 3 0 Trm112p-like protein Ribosomal_S7e PF01251.18 KZN91818.1 - 6.8e-83 276.9 0.1 7.9e-83 276.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DUF1382 PF07131.11 KZN91818.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1382) Ras PF00071.22 KZN91819.1 - 1.2e-56 190.8 0.0 2.1e-56 190.0 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KZN91819.1 - 1.6e-34 118.7 0.0 2.9e-34 117.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KZN91819.1 - 3.2e-14 52.8 0.0 5.5e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KZN91819.1 - 4.7e-06 26.3 0.0 7.1e-06 25.7 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KZN91819.1 - 6.7e-05 22.4 0.0 7.8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KZN91819.1 - 7.4e-05 22.8 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KZN91819.1 - 0.00044 20.7 0.1 0.00088 19.7 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KZN91819.1 - 0.056 13.4 0.0 2 8.3 0.0 2.5 2 1 1 3 3 3 0 RsgA GTPase TniB PF05621.11 KZN91819.1 - 0.2 11.0 0.0 0.43 10.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Acetate_kinase PF00871.17 KZN91820.1 - 8.6e-93 311.1 0.0 1e-92 310.9 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family XFP_N PF09364.10 KZN91821.1 - 2.6e-152 506.9 0.0 3.4e-152 506.5 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 KZN91821.1 - 3.1e-79 265.2 0.0 4.7e-79 264.5 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 KZN91821.1 - 5e-74 247.8 0.0 7.8e-74 247.2 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.21 KZN91821.1 - 0.0031 17.3 0.1 0.0082 15.9 0.1 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_C PF02780.20 KZN91821.1 - 0.14 12.1 0.1 0.38 10.6 0.1 1.7 1 0 0 1 1 1 0 Transketolase, C-terminal domain RTA1 PF04479.13 KZN91824.1 - 3.4e-73 245.7 12.8 5.1e-73 245.1 12.8 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF3339 PF11820.8 KZN91824.1 - 1.3 9.2 8.0 5.5 7.3 0.2 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3339) DUF373 PF04123.13 KZN91826.1 - 0.059 12.8 0.3 0.059 12.8 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF373) AAA_16 PF13191.6 KZN91827.1 - 9.5e-06 26.1 0.1 3.4e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain DUF2193 PF09959.9 KZN91827.1 - 0.054 11.9 0.0 0.08 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2193) AAA_7 PF12775.7 KZN91827.1 - 0.061 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 KZN91827.1 - 0.093 12.7 0.1 0.44 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Meiosis_expr PF15163.6 KZN91827.1 - 0.099 13.3 0.0 0.27 11.9 0.0 1.7 1 0 0 1 1 1 0 Meiosis-expressed CLU PF13236.6 KZN91828.1 - 7e-75 251.7 0.0 1.2e-74 250.9 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 KZN91828.1 - 6.4e-54 182.6 0.0 1.3e-53 181.6 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 KZN91828.1 - 9.1e-27 93.2 6.5 1.6e-13 50.7 0.1 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat CLU_N PF15044.6 KZN91828.1 - 3e-25 88.4 0.1 9.6e-25 86.8 0.1 2.0 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 KZN91828.1 - 3e-23 81.0 0.7 2.4e-07 30.4 0.0 5.2 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KZN91828.1 - 6.8e-06 25.8 2.7 0.37 11.0 0.2 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KZN91828.1 - 0.00074 19.5 5.4 0.068 13.4 0.7 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF727 PF05303.12 KZN91828.1 - 0.023 14.8 0.0 0.065 13.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF727) TPR_17 PF13431.6 KZN91828.1 - 0.66 10.5 2.4 3.2e+02 2.1 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Ferric_reduct PF01794.19 KZN91830.1 - 2e-19 70.0 9.0 2e-19 70.0 9.0 2.7 3 1 1 4 4 4 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KZN91830.1 - 4.5e-19 69.1 0.0 9.2e-17 61.6 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KZN91830.1 - 2.3e-13 50.2 0.0 2.3e-10 40.5 0.0 2.5 1 1 0 1 1 1 1 FAD-binding domain DUF4405 PF14358.6 KZN91830.1 - 7.4 7.2 15.8 12 6.6 1.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) Polysacc_synt_C PF14667.6 KZN91830.1 - 9.4 6.3 9.2 39 4.3 3.4 3.1 3 0 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain Tannase PF07519.11 KZN91831.1 - 9.8e-52 176.4 4.8 1e-32 113.7 0.1 3.0 2 1 1 3 3 3 3 Tannase and feruloyl esterase RTA1 PF04479.13 KZN91831.1 - 4.2e-20 72.3 2.9 4.9e-12 45.9 0.3 2.3 1 1 1 2 2 2 2 RTA1 like protein SusD-like_2 PF12771.7 KZN91831.1 - 0.068 12.1 0.1 0.1 11.5 0.1 1.2 1 0 0 1 1 1 0 Starch-binding associating with outer membrane Peptidase_S9 PF00326.21 KZN91831.1 - 0.073 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family GST_N PF02798.20 KZN91832.1 - 4.5e-15 55.7 0.0 9.9e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KZN91832.1 - 1.2e-14 54.4 0.0 2.3e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KZN91832.1 - 1.3e-12 47.8 0.0 2.8e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KZN91832.1 - 9.4e-10 38.6 0.0 1.9e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KZN91832.1 - 8e-09 35.6 0.0 1.5e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KZN91832.1 - 3.5e-07 30.1 0.0 6.9e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SF1-HH PF16275.5 KZN91833.1 - 4.4e-43 146.2 1.5 4.4e-43 146.2 1.5 2.1 2 0 0 2 2 2 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 KZN91833.1 - 7e-12 44.8 11.1 1.3e-05 25.0 0.8 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 KZN91833.1 - 1.2e-06 28.4 5.6 0.0013 18.6 2.8 2.7 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 KZN91833.1 - 0.0015 18.2 5.0 0.43 10.3 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 KZN91833.1 - 0.0047 16.7 0.1 0.0092 15.8 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_2 PF13696.6 KZN91833.1 - 0.014 15.2 0.5 0.014 15.2 0.5 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 KZN91833.1 - 0.59 10.0 15.7 0.31 10.9 0.5 3.0 3 0 0 3 3 3 0 Zinc knuckle HCO3_cotransp PF00955.21 KZN91834.1 - 1.1e-75 255.4 15.4 2.3e-46 158.7 6.3 2.8 1 1 1 2 2 2 2 HCO3- transporter family DEAD PF00270.29 KZN91835.1 - 3e-41 141.1 0.0 7.5e-41 139.8 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KZN91835.1 - 3e-30 104.8 0.0 6.6e-30 103.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KZN91835.1 - 2e-07 31.2 0.0 7.5e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KZN91835.1 - 0.013 14.3 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain SWI2_SNF2 PF18766.1 KZN91835.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase DUF1793 PF08760.11 KZN91837.1 - 5e-69 232.0 0.2 5e-69 232.0 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 KZN91837.1 - 2e-63 213.2 0.6 9.7e-50 168.6 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 KZN91837.1 - 2.4e-48 164.9 0.1 3.6e-48 164.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 KZN91837.1 - 0.0053 16.3 0.1 0.013 15.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Stm1_N PF09598.10 KZN91838.1 - 3.9e-17 62.8 3.4 3.9e-17 62.8 3.4 5.3 3 1 0 3 3 3 1 Stm1 Epimerase PF01370.21 KZN91839.1 - 7.3e-12 45.3 0.9 2.5e-09 37.0 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KZN91839.1 - 3.3e-11 43.4 0.3 4.7e-11 42.9 0.3 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KZN91839.1 - 4.6e-09 36.2 0.2 7.3e-09 35.5 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 KZN91839.1 - 1.6e-07 30.8 0.1 8.2e-07 28.4 0.1 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KZN91839.1 - 7.7e-06 25.1 0.1 0.00047 19.3 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 KZN91839.1 - 1.7e-05 25.0 0.1 0.00011 22.5 0.0 2.2 3 0 0 3 3 3 1 TrkA-N domain NAD_binding_4 PF07993.12 KZN91839.1 - 6.4e-05 22.3 0.3 0.00047 19.4 0.2 2.0 2 0 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KZN91839.1 - 0.00011 21.8 0.3 0.00043 19.8 0.1 2.0 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 KZN91839.1 - 0.00021 21.6 0.1 0.0005 20.3 0.1 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 KZN91839.1 - 0.00026 20.5 0.3 0.00046 19.7 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Mfa_like_1 PF13149.6 KZN91839.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Fimbrillin-like DapB_N PF01113.20 KZN91839.1 - 0.14 12.3 0.4 0.33 11.1 0.2 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DKCLD PF08068.12 KZN91839.1 - 0.17 12.0 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 DKCLD (NUC011) domain bZIP_1 PF00170.21 KZN91840.1 - 4e-05 23.6 9.5 8e-05 22.7 9.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KZN91840.1 - 0.016 15.3 9.8 0.016 15.3 9.8 2.0 2 0 0 2 2 2 0 Basic region leucine zipper GvpL_GvpF PF06386.11 KZN91840.1 - 0.23 11.4 2.7 0.37 10.7 2.7 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF4407 PF14362.6 KZN91840.1 - 0.65 9.3 3.2 2.8 7.2 3.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Pex19 PF04614.12 KZN91841.1 - 8.4e-76 255.0 4.7 1.4e-75 254.2 4.7 1.3 1 0 0 1 1 1 1 Pex19 protein family Mid2 PF04478.12 KZN91844.1 - 8.9e-09 35.3 0.2 8.9e-09 35.3 0.2 2.8 2 2 0 2 2 2 1 Mid2 like cell wall stress sensor Endomucin PF07010.12 KZN91844.1 - 0.0034 17.4 40.0 0.004 17.2 40.0 1.0 1 0 0 1 1 1 1 Endomucin SKG6 PF08693.10 KZN91844.1 - 0.039 13.3 1.0 0.14 11.5 1.0 2.0 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Presenilin PF01080.17 KZN91844.1 - 0.092 11.5 4.2 0.12 11.2 4.2 1.2 1 0 0 1 1 1 0 Presenilin Utp14 PF04615.13 KZN91844.1 - 0.15 10.6 5.5 0.17 10.5 5.5 1.0 1 0 0 1 1 1 0 Utp14 protein Apt1 PF10351.9 KZN91844.1 - 0.23 10.2 11.4 0.31 9.8 11.4 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain FeoB_associated PF12669.7 KZN91844.1 - 0.85 10.1 3.4 3 8.3 3.4 1.8 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Mrx7 PF10906.8 KZN91846.1 - 5.3e-12 45.8 0.8 9.5e-12 45.0 0.8 1.4 1 1 0 1 1 1 1 MIOREX complex component 7 Fungal_trans_2 PF11951.8 KZN91847.1 - 1.2e-32 113.2 0.2 6.4e-32 110.8 0.2 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN91847.1 - 1.7e-06 28.1 8.0 3.2e-06 27.2 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KZN91848.1 - 2.9e-65 220.3 0.0 3.8e-65 219.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN91848.1 - 1.9e-31 109.3 0.0 2.4e-30 105.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KZN91848.1 - 0.00034 20.0 0.0 0.00062 19.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KZN91848.1 - 0.00093 18.2 0.1 0.0015 17.6 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KZN91848.1 - 0.0048 16.2 0.1 0.024 14.0 0.0 2.1 2 1 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KZN91848.1 - 0.0065 16.1 0.1 0.2 11.3 0.0 2.2 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KZN91848.1 - 0.0069 16.3 0.1 0.017 15.1 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KZN91848.1 - 0.015 14.9 0.0 0.033 13.8 0.0 1.5 1 1 0 1 1 1 0 RIO1 family ANAPC_CDC26 PF10471.9 KZN91849.1 - 0.0044 17.8 0.3 0.01 16.7 0.2 1.9 1 1 1 2 2 2 1 Anaphase-promoting complex APC subunit CDC26 NAD_binding_8 PF13450.6 KZN91850.1 - 3.5e-08 33.6 0.0 9e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KZN91850.1 - 3.5e-05 23.3 0.0 5.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KZN91850.1 - 0.004 16.4 0.1 0.012 14.9 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KZN91850.1 - 0.0041 16.4 0.1 0.0072 15.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KZN91850.1 - 0.0043 16.3 0.0 0.0081 15.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KZN91850.1 - 0.0057 16.1 0.0 0.0083 15.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KZN91850.1 - 0.0076 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KZN91850.1 - 0.048 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 KZN91850.1 - 0.049 12.3 0.0 0.073 11.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 KZN91850.1 - 0.057 12.5 0.1 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 KZN91850.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase TPT PF03151.16 KZN91851.1 - 2.1e-25 89.7 28.0 2.7e-25 89.3 28.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KZN91851.1 - 0.074 12.2 27.6 0.22 10.7 27.6 1.8 1 1 0 1 1 1 0 UAA transporter family TFIIB PF00382.19 KZN91854.1 - 3.9e-32 110.1 0.3 1.9e-16 59.8 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KZN91854.1 - 1.4e-25 89.6 0.0 1.4e-25 89.6 0.0 2.5 4 0 0 4 4 4 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 KZN91854.1 - 8.4e-05 22.0 2.1 0.00021 20.8 2.1 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 KZN91854.1 - 0.00058 19.6 0.1 0.97 9.2 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain IBR PF01485.21 KZN91854.1 - 0.098 12.9 0.8 0.2 11.9 0.8 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain E1-E2_ATPase PF00122.20 KZN91855.1 - 2.3e-50 170.6 0.2 2.2e-49 167.5 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 KZN91855.1 - 9.4e-45 150.9 4.6 6.3e-14 52.2 0.0 5.2 5 0 0 5 5 5 4 Heavy-metal-associated domain Hydrolase PF00702.26 KZN91855.1 - 2.6e-33 116.1 0.1 4.8e-33 115.2 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KZN91855.1 - 3e-07 30.5 0.1 0.001 18.9 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase CmcI PF04989.12 KZN91855.1 - 0.00085 19.1 0.9 0.01 15.6 0.1 2.6 2 0 0 2 2 2 1 Cephalosporin hydroxylase HAD PF12710.7 KZN91855.1 - 0.001 19.5 0.0 0.0041 17.6 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ERCC4 PF02732.15 KZN91856.1 - 2.6e-25 89.5 0.0 4e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain Epimerase PF01370.21 KZN91858.1 - 1e-19 71.0 0.0 1.3e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KZN91858.1 - 3.1e-13 49.8 0.0 2.7e-08 33.6 0.0 2.3 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KZN91858.1 - 7.3e-11 41.6 0.0 9.3e-11 41.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KZN91858.1 - 4.7e-06 25.9 0.0 0.077 12.2 0.0 2.7 2 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KZN91858.1 - 5.4e-06 25.7 0.0 1.5e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KZN91858.1 - 0.00017 21.5 0.0 0.00028 20.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KZN91858.1 - 0.0093 15.9 0.0 1 9.3 0.0 2.3 2 0 0 2 2 2 1 KR domain Ldh_1_N PF00056.23 KZN91858.1 - 0.034 14.2 0.0 0.074 13.1 0.0 1.5 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KZN91858.1 - 0.042 13.0 0.0 1.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein adh_short PF00106.25 KZN91858.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.6 1 1 0 1 1 1 0 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 KZN91858.1 - 0.19 12.0 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Fungal_trans PF04082.18 KZN91859.1 - 7.6e-07 28.4 0.3 1.8e-06 27.2 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN91859.1 - 3.2e-06 27.2 10.8 5.4e-06 26.4 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ChAPs PF09295.10 KZN91861.1 - 1.8e-156 521.2 0.0 2.2e-156 520.8 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.6 KZN91861.1 - 4.6e-05 23.9 1.0 0.13 13.2 0.1 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KZN91861.1 - 6.3e-05 22.6 0.0 4.7 7.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KZN91861.1 - 0.00011 22.7 0.1 0.38 11.3 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KZN91861.1 - 0.00024 21.0 0.4 0.52 10.6 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 KZN91861.1 - 0.00056 19.2 1.2 0.2 10.8 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KZN91861.1 - 0.0008 19.3 0.6 10 6.4 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KZN91861.1 - 0.0024 18.1 0.3 2.8 8.3 0.1 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KZN91861.1 - 0.0033 17.5 0.0 4.4 7.8 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KZN91861.1 - 0.057 13.6 0.1 1.7 8.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KZN91862.1 - 0.048 13.3 2.2 0.12 12.1 2.2 1.7 1 0 0 1 1 1 0 TPR repeat TPR_19 PF14559.6 KZN91862.1 - 0.51 10.9 2.8 1.2e+02 3.3 0.7 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Kinesin PF00225.23 KZN91863.1 - 1.2e-59 201.9 0.0 1.7e-59 201.4 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KZN91863.1 - 2.6e-12 46.9 0.0 3.5e-10 40.0 0.0 2.4 2 0 0 2 2 2 2 Microtubule binding bZIP_2 PF07716.15 KZN91863.1 - 0.0022 18.0 2.0 0.0059 16.7 2.0 1.7 1 0 0 1 1 1 1 Basic region leucine zipper DUF87 PF01935.17 KZN91863.1 - 8.3 6.4 5.3 6.1 6.9 0.5 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain RTA1 PF04479.13 KZN91864.1 - 1.3e-16 60.9 3.9 1.6e-16 60.5 3.9 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF3112 PF11309.8 KZN91864.1 - 0.038 13.4 0.3 0.052 13.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) MFS_1 PF07690.16 KZN91865.1 - 3.1e-31 108.6 38.2 1.8e-30 106.1 38.1 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN91865.1 - 1.7e-09 37.0 30.2 1.1e-08 34.4 30.2 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter Peptidase_S24 PF00717.23 KZN91866.1 - 2.2e-05 24.3 0.0 3.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like UQ_con PF00179.26 KZN91867.1 - 1.4e-41 141.4 0.0 1.6e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KZN91867.1 - 0.00032 20.4 0.0 0.00041 20.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KZN91867.1 - 0.017 15.4 0.1 0.022 15.0 0.1 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 KZN91867.1 - 0.045 13.6 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain UCR_6-4kD PF08997.10 KZN91867.1 - 0.12 12.3 0.2 1.3 9.0 0.1 2.3 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein TAL_effector PF03377.13 KZN91869.1 - 0.18 12.1 0.0 2 8.8 0.0 2.2 2 0 0 2 2 2 0 TAL effector repeat F_bP_aldolase PF01116.20 KZN91871.1 - 6.8e-93 311.2 0.0 7.7e-93 311.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II UCH PF00443.29 KZN91872.1 - 3.2e-38 131.7 0.0 1.8e-33 116.2 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KZN91872.1 - 6.5e-10 39.1 1.1 7.7e-09 35.6 1.1 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase AlaDh_PNT_N PF05222.15 KZN91873.1 - 6.4e-30 104.2 0.0 1e-29 103.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KZN91873.1 - 6.4e-05 22.3 0.0 0.00085 18.7 0.0 2.2 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain CUE PF02845.16 KZN91876.1 - 3e-08 33.2 0.0 4.7e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 CUE domain DUF3697 PF12478.8 KZN91876.1 - 0.0082 16.2 0.2 0.032 14.3 0.2 2.0 1 0 0 1 1 1 1 Ubiquitin-associated protein 2 MFS_1 PF07690.16 KZN91878.1 - 2.4e-40 138.6 41.0 2.7e-39 135.1 37.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN91878.1 - 5.1e-07 28.9 12.8 5.1e-07 28.9 12.8 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KZN91878.1 - 0.17 10.1 5.0 0.56 8.4 4.0 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ATG22 PF11700.8 KZN91879.1 - 5e-118 394.8 17.8 5.7e-118 394.6 17.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KZN91879.1 - 5.7e-11 41.9 38.2 2.4e-07 30.0 13.8 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily COX16 PF14138.6 KZN91879.1 - 0.041 14.4 0.3 3.1 8.4 0.1 2.7 3 0 0 3 3 3 0 Cytochrome c oxidase assembly protein COX16 DUF4381 PF14316.6 KZN91879.1 - 0.048 13.9 2.6 0.09 13.0 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4381) Glyco_hydro_3 PF00933.21 KZN91880.1 - 2.6e-88 296.5 0.0 3.5e-88 296.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 KZN91880.1 - 9.5e-16 58.1 0.0 9.1e-08 32.4 0.0 2.8 3 0 0 3 3 3 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KZN91880.1 - 3.9e-13 49.6 0.1 3.9e-07 30.4 0.0 2.7 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KZN91880.1 - 3.2e-11 43.3 0.0 9.4e-08 32.0 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.22 KZN91880.1 - 0.00021 21.3 0.0 0.00056 19.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_6 PF13480.7 KZN91880.1 - 0.0016 18.6 0.1 0.056 13.6 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KZN91880.1 - 0.0071 16.4 0.0 2.9 8.0 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 KZN91880.1 - 0.024 14.6 0.0 0.26 11.3 0.0 2.4 2 0 0 2 2 2 0 FR47-like protein MmlI PF09448.10 KZN91880.1 - 0.043 14.3 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 Methylmuconolactone methyl-isomerase GST_N PF02798.20 KZN91881.1 - 7.6e-17 61.4 0.0 1.6e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KZN91881.1 - 1.8e-13 50.7 0.0 3.3e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KZN91881.1 - 4.1e-12 46.2 0.0 6.5e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KZN91881.1 - 1.4e-09 38.1 0.0 2.8e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KZN91881.1 - 4.4e-08 33.2 0.0 1.1e-07 32.0 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KZN91881.1 - 4.9e-07 29.7 0.0 1.4e-06 28.2 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KZN91881.1 - 0.018 14.9 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KZN91881.1 - 0.088 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein TcdA_TcdB PF12919.7 KZN91881.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Sacchrp_dh_C PF16653.5 KZN91882.1 - 3.3e-68 230.6 0.0 7.5e-68 229.5 0.0 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KZN91882.1 - 4.4e-22 78.7 0.1 6.2e-22 78.3 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KZN91882.1 - 2.8e-07 30.7 0.0 5.5e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KZN91882.1 - 0.00022 21.2 0.2 0.00035 20.5 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KZN91882.1 - 0.029 14.8 0.0 0.066 13.6 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KZN91882.1 - 0.061 14.1 0.0 0.1 13.4 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 KZN91882.1 - 0.08 13.5 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sugar_tr PF00083.24 KZN91883.1 - 1.4e-90 304.3 22.5 1.8e-90 304.0 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN91883.1 - 2.4e-17 62.9 64.3 1.8e-14 53.5 29.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cwf_Cwc_15 PF04889.12 KZN91884.1 - 0.087 12.5 16.0 0.32 10.7 4.6 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RNase_T PF00929.24 KZN91885.1 - 4.7e-27 95.5 0.0 5.4e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Exonuclease PGM_PMM_I PF02878.16 KZN91886.1 - 8.7e-32 109.7 0.0 1.3e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KZN91886.1 - 4e-26 91.4 0.0 6.9e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KZN91886.1 - 6.4e-17 62.1 0.0 1.7e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KZN91886.1 - 2.8e-07 30.6 0.0 6.9e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain GFO_IDH_MocA PF01408.22 KZN91887.1 - 2.7e-10 41.1 0.0 8e-10 39.6 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KZN91887.1 - 4.8e-05 23.4 0.0 0.0001 22.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain K_oxygenase PF13434.6 KZN91888.1 - 5.4e-17 62.0 0.0 1.7e-11 43.9 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KZN91888.1 - 1.2e-06 28.0 0.2 0.0096 15.2 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KZN91888.1 - 1.5e-05 25.0 0.1 0.29 11.1 0.1 3.3 3 1 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KZN91888.1 - 2.5e-05 23.7 0.0 0.19 10.9 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KZN91888.1 - 7.5e-05 22.5 1.1 0.54 9.8 0.0 3.7 3 1 0 4 4 4 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KZN91888.1 - 0.00088 19.3 0.0 0.3 11.1 0.1 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 KZN91888.1 - 0.0013 18.0 0.0 0.0095 15.2 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KZN91888.1 - 0.0026 16.9 0.0 0.036 13.1 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KZN91888.1 - 0.0027 16.8 0.7 0.0066 15.5 0.1 1.9 2 1 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 KZN91888.1 - 0.0028 16.4 0.0 0.096 11.4 0.0 2.3 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 KZN91888.1 - 0.0037 16.4 0.4 0.27 10.3 0.0 2.4 2 1 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KZN91888.1 - 0.0086 16.3 0.2 0.16 12.3 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KZN91888.1 - 0.012 14.9 0.3 0.05 12.8 0.0 2.1 3 0 0 3 3 3 0 FAD binding domain TrkA_N PF02254.18 KZN91888.1 - 0.18 12.1 0.0 0.5 10.7 0.0 1.8 2 0 0 2 2 1 0 TrkA-N domain SR-25 PF10500.9 KZN91888.1 - 0.22 11.1 11.1 0.13 11.9 7.0 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein FIT1_2 PF17357.2 KZN91888.1 - 3.1 7.9 9.3 0.52 10.4 0.1 3.0 3 0 0 3 3 3 0 Facilitor Of iron transport 1 and 2 HMG_CoA_synt_C PF08540.10 KZN91890.1 - 2.6e-105 352.0 0.6 3.3e-105 351.7 0.6 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KZN91890.1 - 4.1e-96 319.8 0.4 7.4e-96 319.0 0.4 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal TFR_dimer PF04253.15 KZN91891.1 - 1.1e-36 125.5 0.1 2.1e-36 124.7 0.1 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KZN91891.1 - 3.7e-20 72.5 0.0 7.4e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KZN91891.1 - 2.1e-12 46.9 0.0 3.9e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KZN91891.1 - 0.021 14.5 0.0 0.059 13.0 0.0 1.8 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 Fungal_trans PF04082.18 KZN91892.1 - 8.5e-05 21.7 0.0 0.00018 20.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN91892.1 - 0.00014 21.9 8.4 0.00014 21.9 8.4 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPP_enzyme_N PF02776.18 KZN91893.1 - 4.1e-33 114.4 0.0 6.7e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KZN91893.1 - 1.5e-18 66.9 0.0 3.6e-18 65.6 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KZN91893.1 - 3.6e-15 56.1 0.2 1.2e-13 51.1 0.1 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF1765 PF08578.10 KZN91894.1 - 4.2e-45 153.3 6.6 1.2e-44 151.8 6.6 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) ATP_sub_h PF10775.9 KZN91895.1 - 1.5e-28 98.6 1.9 2.1e-28 98.1 1.9 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.11 KZN91895.1 - 0.016 15.6 0.0 0.023 15.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 TFIIB PF00382.19 KZN91896.1 - 1.1e-39 134.2 0.2 8.9e-20 70.5 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KZN91896.1 - 6.5e-11 41.6 1.1 6.5e-11 41.6 1.1 1.8 2 0 0 2 2 2 1 TFIIB zinc-binding Cyclin_N PF00134.23 KZN91896.1 - 0.00063 19.5 0.3 0.79 9.5 0.1 2.4 2 1 0 2 2 2 2 Cyclin, N-terminal domain RB_B PF01857.20 KZN91896.1 - 0.0012 18.9 0.0 0.0024 17.9 0.0 1.5 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain Cyclin_C PF02984.19 KZN91896.1 - 0.021 14.9 0.0 0.67 10.0 0.0 2.2 2 0 0 2 2 2 0 Cyclin, C-terminal domain TMIE PF16038.5 KZN91896.1 - 0.12 12.2 0.3 0.21 11.4 0.3 1.4 1 0 0 1 1 1 0 TMIE protein Sigma70_r4_2 PF08281.12 KZN91896.1 - 0.19 11.4 0.0 0.57 9.9 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_r4 PF04545.16 KZN91896.1 - 0.2 11.2 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 DUF1610 PF07754.11 KZN91896.1 - 0.35 10.9 2.6 1.2 9.2 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-ribbon_3 PF13248.6 KZN91896.1 - 6.4 6.3 8.1 6.2 6.4 3.5 2.6 2 1 0 2 2 2 0 zinc-ribbon domain NAM-associated PF14303.6 KZN91897.1 - 0.034 14.9 2.3 0.04 14.7 2.3 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Kri1 PF05178.12 KZN91897.1 - 0.043 14.4 0.2 0.055 14.0 0.2 1.2 1 0 0 1 1 1 0 KRI1-like family Mucin PF01456.17 KZN91897.1 - 0.18 11.8 4.9 0.22 11.5 4.9 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein AvrPtoB-E3_ubiq PF09046.10 KZN91898.1 - 0.15 12.3 0.8 2.8 8.2 0.2 2.2 2 0 0 2 2 2 0 AvrPtoB E3 ubiquitin ligase DIL PF01843.19 KZN91899.1 - 1.3e-30 105.7 1.1 1.3e-30 105.7 1.1 1.8 2 0 0 2 2 2 1 DIL domain Ank_2 PF12796.7 KZN91899.1 - 3.6e-13 49.9 0.0 1.3e-12 48.1 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KZN91899.1 - 3.1e-09 36.9 0.0 0.0008 19.7 0.0 3.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KZN91899.1 - 4e-07 30.5 0.0 0.0024 18.4 0.1 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KZN91899.1 - 4.9e-07 29.9 0.0 0.041 14.3 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KZN91899.1 - 9.2e-06 25.6 0.1 0.015 15.8 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat DUF3349 PF11829.8 KZN91899.1 - 0.025 15.4 0.6 0.078 13.8 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) RasGEF PF00617.19 KZN91900.1 - 3.8e-44 151.0 0.6 7.3e-44 150.1 0.6 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KZN91900.1 - 3e-13 49.9 1.0 6.8e-13 48.8 1.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Peptidase_M13_N PF05649.13 KZN91901.1 - 6.1e-94 315.8 0.0 9.1e-94 315.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KZN91901.1 - 6.4e-61 205.5 0.1 1e-60 204.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M13 RicinB_lectin_2 PF14200.6 KZN91902.1 - 0.0078 16.9 0.1 0.096 13.4 0.0 2.2 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like DUF3048_C PF17479.2 KZN91902.1 - 0.052 13.9 0.0 0.08 13.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3048) C-terminal domain FMN_dh PF01070.18 KZN91903.1 - 3.9e-109 364.9 0.0 4.7e-109 364.6 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KZN91903.1 - 2.4e-06 27.0 0.0 6e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.25 KZN91903.1 - 1e-05 24.7 0.1 3.1e-05 23.2 0.1 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KZN91903.1 - 0.0015 18.0 0.2 0.16 11.4 0.0 2.5 2 1 1 3 3 3 2 Histidine biosynthesis protein PHP PF02811.19 KZN91903.1 - 0.087 13.1 0.0 16 5.8 0.0 2.2 2 0 0 2 2 2 0 PHP domain ThiG PF05690.14 KZN91903.1 - 0.11 11.8 0.0 3.2 7.0 0.0 2.5 3 0 0 3 3 3 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 KZN91903.1 - 0.17 11.1 0.0 1.6 7.9 0.0 2.0 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase MFS_1 PF07690.16 KZN91905.1 - 2.3e-18 66.3 21.4 2.3e-18 66.3 21.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily TM_helix PF05552.12 KZN91905.1 - 1.5 8.9 0.0 1.5 8.9 0.0 3.0 3 0 0 3 3 3 0 Conserved TM helix G-alpha PF00503.20 KZN91906.1 - 1.1e-108 363.6 0.2 1.3e-108 363.4 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KZN91906.1 - 4.3e-14 52.3 0.1 2.7e-09 36.7 0.0 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KZN91906.1 - 1.1e-06 28.1 0.2 0.0013 18.1 0.1 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KZN91906.1 - 0.0013 18.8 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase Roc PF08477.13 KZN91906.1 - 0.0038 17.4 0.0 0.81 9.9 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF1967 PF09269.11 KZN91906.1 - 0.013 15.4 0.1 19 5.3 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1967) GTP_EFTU PF00009.27 KZN91906.1 - 0.063 12.8 0.0 4.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 KZN91906.1 - 0.069 12.5 0.0 0.29 10.4 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.6 KZN91906.1 - 0.085 13.2 0.0 0.23 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 KZN91906.1 - 0.09 12.5 0.2 0.19 11.5 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 KZN91906.1 - 0.099 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein DUF1713 PF08213.11 KZN91907.1 - 6.9e-12 45.1 20.1 1.4e-11 44.1 20.1 1.5 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.10 KZN91907.1 - 0.052 14.3 0.0 0.34 11.6 0.0 2.5 1 1 0 1 1 1 0 Mitochondrial protein Pet20 DUF1180 PF06679.12 KZN91907.1 - 1.6 9.2 7.6 2.1 8.7 4.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) SR-25 PF10500.9 KZN91907.1 - 3.9 7.0 20.5 2.3 7.8 1.2 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ATP-synt_C PF00137.21 KZN91908.1 - 3.1e-29 101.1 24.1 3e-22 78.7 14.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C GerA PF03323.13 KZN91908.1 - 0.69 8.3 3.1 6.2 5.2 0.4 2.2 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein SH PF01445.17 KZN91908.1 - 2.2 8.3 4.6 2.9 7.9 0.2 2.4 2 1 1 3 3 3 0 Viral small hydrophobic protein Pmp3 PF01679.17 KZN91910.1 - 2e-25 88.7 9.1 2.3e-25 88.5 9.1 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator CFEM PF05730.11 KZN91911.1 - 9.4e-05 22.4 6.8 0.0002 21.4 6.8 1.5 1 0 0 1 1 1 1 CFEM domain Macoilin PF09726.9 KZN91911.1 - 1.8 7.0 7.9 3.5 6.1 7.9 1.4 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 KZN91911.1 - 6.2 5.6 10.7 0.3 9.9 3.4 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain F-box-like PF12937.7 KZN91912.1 - 0.041 13.8 0.1 0.12 12.2 0.1 1.8 1 0 0 1 1 1 0 F-box-like LRR_4 PF12799.7 KZN91912.1 - 0.25 11.8 1.7 19 5.8 0.0 3.6 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Hydrolase_6 PF13344.6 KZN91913.1 - 1.3e-21 76.6 0.0 2.5e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KZN91913.1 - 5.7e-13 48.7 0.0 2.2e-12 46.8 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Lipase_3 PF01764.25 KZN91913.1 - 0.034 14.0 0.0 0.096 12.6 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Hydrolase PF00702.26 KZN91913.1 - 0.09 13.0 0.0 8.4 6.6 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase tRNA-synt_2c PF01411.19 KZN91914.1 - 2.7e-11 42.7 0.0 3.6e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KZN91914.1 - 1.4e-08 34.7 0.8 2.8e-08 33.7 0.8 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF676 PF05057.14 KZN91915.1 - 1.6e-46 158.5 0.0 2.5e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KZN91915.1 - 8.7e-05 22.5 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 KZN91915.1 - 0.00016 22.4 0.0 0.00025 21.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 KZN91915.1 - 0.00017 21.4 0.0 0.00029 20.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 KZN91915.1 - 0.00037 20.3 0.0 0.0015 18.3 0.0 2.2 1 1 0 1 1 1 1 PGAP1-like protein DUF2235 PF09994.9 KZN91915.1 - 0.028 13.8 0.1 0.49 9.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) LCAT PF02450.15 KZN91915.1 - 0.047 12.8 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DLH PF01738.18 KZN91915.1 - 0.096 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KZN91915.1 - 0.13 12.1 0.1 1.9 8.2 0.0 2.2 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Lipase_2 PF01674.18 KZN91915.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) NAM-associated PF14303.6 KZN91916.1 - 0.55 10.9 7.1 0.074 13.8 2.9 1.7 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Ribosomal_L22e PF01776.17 KZN91917.1 - 7.9e-48 161.4 0.4 9.7e-48 161.1 0.4 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DIM1 PF02966.16 KZN91918.1 - 5.4e-70 233.3 0.3 6.1e-70 233.2 0.3 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KZN91918.1 - 0.05 13.6 0.0 0.064 13.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DUF3192 PF11399.8 KZN91918.1 - 0.053 13.5 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) Translin PF01997.16 KZN91919.1 - 2.2e-50 171.5 0.0 2.6e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Translin family DUF5631 PF18645.1 KZN91919.1 - 0.035 14.5 0.4 0.098 13.1 0.4 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5631) FRQ PF09421.10 KZN91919.1 - 0.04 12.0 0.2 0.053 11.6 0.2 1.1 1 0 0 1 1 1 0 Frequency clock protein GMP_synt_C PF00958.22 KZN91919.1 - 0.06 13.4 0.1 0.6 10.2 0.0 2.2 2 0 0 2 2 2 0 GMP synthase C terminal domain Rx_N PF18052.1 KZN91919.1 - 0.081 13.2 2.7 1.9 8.8 0.8 3.1 2 1 0 2 2 2 0 Rx N-terminal domain Syntaxin_2 PF14523.6 KZN91919.1 - 0.12 12.8 0.9 0.26 11.7 0.9 1.5 1 0 0 1 1 1 0 Syntaxin-like protein GSHPx PF00255.19 KZN91920.1 - 1.8e-38 130.4 0.0 2.5e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KZN91920.1 - 0.024 14.5 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Ral PF11058.8 KZN91920.1 - 0.15 11.6 0.1 0.28 10.8 0.1 1.4 1 0 0 1 1 1 0 Antirestriction protein Ral DSPn PF14671.6 KZN91922.1 - 2.9e-43 147.7 0.0 8.9e-41 139.6 0.0 2.9 2 1 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KZN91922.1 - 7.1e-17 61.5 0.0 6.5e-16 58.4 0.0 2.4 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KZN91922.1 - 1.3e-05 24.9 0.1 4.4e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Ku_PK_bind PF08785.11 KZN91923.1 - 8.8e-38 129.1 0.0 2.3e-37 127.8 0.0 1.8 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.16 KZN91923.1 - 3.5e-34 118.3 0.0 7.4e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KZN91923.1 - 3.5e-10 40.0 0.0 1.3e-09 38.1 0.0 1.9 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 KZN91923.1 - 0.00048 20.4 0.7 0.00048 20.4 0.7 2.5 3 1 1 4 4 4 1 von Willebrand factor type A domain DUF4149 PF13664.6 KZN91924.1 - 6e-28 97.2 3.7 1.9e-27 95.5 2.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF1772 PF08592.11 KZN91924.1 - 0.011 16.0 0.2 0.014 15.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) DAO PF01266.24 KZN91925.1 - 9.5e-26 91.2 0.2 1.2e-25 90.8 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KZN91925.1 - 0.0021 18.6 0.6 0.01 16.4 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KZN91925.1 - 0.027 13.7 0.1 0.05 12.8 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KZN91925.1 - 0.07 12.4 0.3 0.3 10.3 0.0 2.0 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.19 KZN91925.1 - 0.096 11.9 0.3 0.15 11.2 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KZN91925.1 - 0.098 11.9 0.3 0.19 10.9 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HNH_3 PF13392.6 KZN91926.1 - 0.13 12.1 0.1 0.32 10.8 0.1 1.6 1 0 0 1 1 1 0 HNH endonuclease WDCP PF15390.6 KZN91926.1 - 0.2 10.0 3.2 0.26 9.6 3.2 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family MADF_DNA_bdg PF10545.9 KZN91926.1 - 3.5 8.0 5.8 1.1 9.6 0.6 2.5 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like BNR_2 PF13088.6 KZN91927.1 - 1.5e-06 27.7 0.0 3.4e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 KZN91927.1 - 0.00017 21.1 4.1 0.14 12.2 0.1 3.9 3 0 0 3 3 3 2 BNR/Asp-box repeat BNR_6 PF15899.5 KZN91927.1 - 0.0031 17.4 0.1 0.014 15.4 0.1 2.2 2 0 0 2 2 2 1 BNR-Asp box repeat Sortilin-Vps10 PF15902.5 KZN91927.1 - 0.006 15.4 0.1 0.44 9.3 0.0 2.2 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, ABC_tran PF00005.27 KZN91928.1 - 2.1e-47 161.1 0.1 1.7e-26 93.3 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KZN91928.1 - 1.3e-17 64.4 28.6 4.3e-14 52.8 7.9 3.7 3 1 0 3 3 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KZN91928.1 - 2.6e-08 33.6 8.6 0.0045 16.4 2.6 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KZN91928.1 - 1.7e-07 30.8 1.2 0.021 14.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 KZN91928.1 - 7.9e-06 25.1 0.2 0.024 13.7 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_7 PF12775.7 KZN91928.1 - 8.2e-06 25.4 0.1 0.088 12.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_16 PF13191.6 KZN91928.1 - 2.1e-05 25.0 0.0 0.21 12.0 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KZN91928.1 - 2.3e-05 24.4 0.1 0.044 13.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase FtsK_SpoIIIE PF01580.18 KZN91928.1 - 6.2e-05 22.5 0.6 0.057 12.8 0.1 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_23 PF13476.6 KZN91928.1 - 8e-05 23.2 0.0 0.36 11.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KZN91928.1 - 0.00011 22.1 1.7 0.14 11.9 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KZN91928.1 - 0.00011 22.5 2.9 0.25 11.6 0.3 3.5 2 2 0 2 2 2 2 AAA domain DUF87 PF01935.17 KZN91928.1 - 0.00018 21.7 1.1 0.0081 16.3 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 KZN91928.1 - 0.00049 19.1 0.5 0.095 11.6 0.1 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.23 KZN91928.1 - 0.0022 18.0 0.2 1.8 8.7 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KZN91928.1 - 0.004 17.3 0.2 2.5 8.2 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KZN91928.1 - 0.0046 16.8 0.1 1.1 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 KZN91928.1 - 0.0047 17.0 2.1 1.3 9.0 0.2 2.6 2 0 0 2 2 2 2 Dynamin family DUF815 PF05673.13 KZN91928.1 - 0.011 14.9 0.1 0.54 9.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 KZN91928.1 - 0.017 14.4 0.0 1.6 7.9 0.0 2.9 2 1 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 KZN91928.1 - 0.018 14.8 0.5 4.1 7.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KZN91928.1 - 0.021 15.2 0.4 18 5.8 0.0 3.4 4 0 0 4 4 3 0 RNA helicase AAA_18 PF13238.6 KZN91928.1 - 0.03 14.9 0.0 8.8 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KZN91928.1 - 0.031 13.9 0.2 3.5 7.2 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 KZN91928.1 - 0.036 13.9 0.4 4.7 6.9 0.3 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 KZN91928.1 - 0.037 13.8 0.2 8 6.1 0.0 2.9 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KZN91928.1 - 0.061 12.6 1.5 8.4 5.6 0.0 2.7 3 0 0 3 3 2 0 Zeta toxin NACHT PF05729.12 KZN91928.1 - 0.14 12.0 0.7 12 5.8 0.0 3.3 3 0 0 3 3 3 0 NACHT domain Pox_A32 PF04665.12 KZN91928.1 - 0.26 10.7 1.5 3.8 6.9 0.0 2.9 3 0 0 3 3 3 0 Poxvirus A32 protein ADH_zinc_N_2 PF13602.6 KZN91931.1 - 7.7e-18 65.8 0.3 1.4e-17 65.0 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KZN91931.1 - 2.6e-11 43.6 3.1 5.5e-11 42.6 2.6 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KZN91931.1 - 0.00094 19.0 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KZN91931.1 - 0.01 15.3 0.3 0.016 14.6 0.3 1.4 1 0 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.20 KZN91931.1 - 0.21 11.7 0.9 0.34 11.1 0.9 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Glyco_hydro_3_C PF01915.22 KZN91932.1 - 5.9e-53 179.8 0.0 8.7e-53 179.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KZN91932.1 - 1.1e-38 133.4 0.1 2.7e-38 132.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KZN91932.1 - 2e-17 63.0 0.1 4.4e-17 61.9 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain bZIP_1 PF00170.21 KZN91933.1 - 0.0011 19.0 13.5 0.0047 17.0 13.5 2.0 1 1 1 2 2 2 1 bZIP transcription factor DUF4748 PF15932.5 KZN91933.1 - 3.9 7.3 5.5 9 6.1 5.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) PT PF04886.12 KZN91933.1 - 7 6.3 17.9 6.5 6.4 0.2 3.5 3 0 0 3 3 3 0 PT repeat EBP PF05241.12 KZN91934.1 - 0.00025 20.5 7.8 0.0015 18.0 7.8 2.1 1 1 0 1 1 1 1 Emopamil binding protein TraD_N PF12615.8 KZN91934.1 - 0.013 16.3 1.0 0.031 15.0 1.0 1.7 1 0 0 1 1 1 0 F sex factor protein N terminal Glyco_trans_4_5 PF16994.5 KZN91934.1 - 0.061 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl-transferase family 4 Fungal_trans PF04082.18 KZN91935.1 - 2.5e-25 89.0 0.0 4.3e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN91935.1 - 3.2e-09 36.8 11.9 5.1e-09 36.1 11.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain hDGE_amylase PF14701.6 KZN91935.1 - 0.15 11.2 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Man-6-P_recep PF02157.15 KZN91936.1 - 2.2e-15 56.5 0.0 3e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 KZN91936.1 - 2.4e-11 44.0 0.0 5.6e-11 42.8 0.0 1.6 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 KZN91936.1 - 4.5e-09 36.5 0.1 4.8e-05 23.5 0.1 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat SelK_SelG PF10961.8 KZN91936.1 - 0.082 13.5 0.6 0.21 12.2 0.6 1.6 1 0 0 1 1 1 0 Selenoprotein SelK_SelG ERG4_ERG24 PF01222.17 KZN91937.1 - 9.6e-158 525.4 6.0 1.1e-157 525.3 6.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KZN91937.1 - 5.8e-05 22.7 0.1 0.00016 21.3 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) zf-MYND PF01753.18 KZN91938.1 - 5.1e-11 42.5 9.3 1e-10 41.5 9.3 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KZN91938.1 - 0.12 12.7 6.0 0.25 11.7 6.0 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding SF3b10 PF07189.11 KZN91939.1 - 5e-35 119.5 0.0 5.6e-35 119.3 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DUF3074 PF11274.8 KZN91940.1 - 2e-55 187.7 1.1 3.3e-55 186.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) START PF01852.19 KZN91940.1 - 0.0012 18.2 0.1 0.32 10.3 0.0 2.7 3 0 0 3 3 3 2 START domain DUF4618 PF15397.6 KZN91940.1 - 0.8 9.1 16.7 0.034 13.6 4.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Seryl_tRNA_N PF02403.22 KZN91940.1 - 4.8 7.5 24.1 1.2 9.4 9.8 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.11 KZN91940.1 - 5.2 7.5 6.1 21 5.6 0.5 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Phage_GP20 PF06810.11 KZN91942.1 - 0.013 15.3 7.6 0.017 14.9 7.6 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 APG6_N PF17675.1 KZN91942.1 - 0.015 15.8 6.3 0.02 15.4 6.3 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region SKA1 PF07160.12 KZN91942.1 - 0.029 14.2 5.8 0.034 14.0 5.8 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 UPF0242 PF06785.11 KZN91942.1 - 0.039 14.1 8.1 0.047 13.8 8.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CdvA PF18822.1 KZN91942.1 - 0.049 13.5 11.0 0.07 13.0 11.0 1.2 1 0 0 1 1 1 0 CdvA-like coiled-coil domain PRKCSH-like PF12999.7 KZN91942.1 - 0.055 13.3 1.6 0.068 13.0 1.6 1.1 1 0 0 1 1 1 0 Glucosidase II beta subunit-like BRE1 PF08647.11 KZN91942.1 - 0.11 12.6 13.3 0.15 12.1 13.3 1.2 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Spc7 PF08317.11 KZN91942.1 - 0.11 11.3 9.2 0.13 11.1 9.2 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DAAD PF18752.1 KZN91942.1 - 0.17 11.7 2.6 0.21 11.4 2.6 1.1 1 0 0 1 1 1 0 Dictyosteliid AID/APOBEC-like Deaminase DUF2951 PF11166.8 KZN91942.1 - 0.2 11.9 5.9 0.26 11.5 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) ADIP PF11559.8 KZN91942.1 - 0.38 10.8 9.8 0.49 10.5 9.8 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding PIN_12 PF16289.5 KZN91942.1 - 0.46 11.0 6.2 0.58 10.6 6.2 1.1 1 0 0 1 1 1 0 PIN domain TP53IP5 PF15331.6 KZN91942.1 - 0.57 10.3 8.3 0.73 9.9 8.3 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF4407 PF14362.6 KZN91942.1 - 1.1 8.5 5.3 1.4 8.2 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_S49_N PF08496.10 KZN91942.1 - 2.1 8.4 9.8 2.6 8.1 9.8 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TMPIT PF07851.13 KZN91942.1 - 3.8 6.7 9.0 4.5 6.4 9.0 1.0 1 0 0 1 1 1 0 TMPIT-like protein NT-C2 PF10358.9 KZN91943.1 - 1.8e-32 112.1 0.0 2.9e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins SLS PF14611.6 KZN91944.1 - 1.1e-32 113.7 0.0 1.8e-32 113.0 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Myotub-related PF06602.14 KZN91945.1 - 3e-150 500.0 0.0 3.8e-150 499.7 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain PAZ PF02170.22 KZN91945.1 - 0.094 12.5 0.0 0.47 10.3 0.0 2.0 2 0 0 2 2 2 0 PAZ domain Ribosomal_S3_C PF00189.20 KZN91946.1 - 9.6e-25 86.9 0.1 5e-24 84.6 0.2 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KZN91946.1 - 8.4e-12 44.8 0.0 1.5e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 KZN91946.1 - 0.1 13.1 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 KZN91946.1 - 0.13 12.1 0.1 0.32 10.8 0.0 1.6 2 0 0 2 2 2 0 Coilin N-terminus Glyco_transf_8 PF01501.20 KZN91947.1 - 8.1e-26 91.1 0.1 5.4e-25 88.4 0.1 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 KZN91947.1 - 0.00011 22.3 0.0 0.00018 21.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Prok-E2_E PF14462.6 KZN91947.1 - 0.32 10.8 1.9 0.87 9.4 0.1 2.4 3 0 0 3 3 3 0 Prokaryotic E2 family E Abhydrolase_6 PF12697.7 KZN91948.1 - 1.9e-13 51.6 0.2 5.1e-12 46.9 0.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KZN91948.1 - 1.8e-10 40.9 0.0 3.1e-10 40.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KZN91948.1 - 3.6e-05 23.1 0.0 5.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 KZN91948.1 - 0.13 12.6 0.2 0.27 11.6 0.2 1.5 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Aldolase PF01081.19 KZN91948.1 - 0.18 11.2 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 KDPG and KHG aldolase Glyco_transf_90 PF05686.12 KZN91949.1 - 2.8e-17 62.7 12.2 1.6e-14 53.7 9.3 3.2 2 1 0 2 2 2 2 Glycosyl transferase family 90 Ferric_reduct PF01794.19 KZN91950.1 - 5e-16 58.9 2.7 5e-16 58.9 2.7 2.3 2 1 0 2 2 2 1 Ferric reductase like transmembrane component Cyt_bd_oxida_II PF02322.15 KZN91950.1 - 0.0097 15.3 12.3 0.045 13.1 12.6 1.9 1 1 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II DUF2678 PF10856.8 KZN91950.1 - 0.34 10.9 2.9 0.19 11.7 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) CoatB PF10389.9 KZN91950.1 - 0.6 10.0 3.2 2.9 7.8 0.3 2.5 2 0 0 2 2 2 0 Bacteriophage coat protein B HEAT PF02985.22 KZN91951.1 - 1.7e-38 127.3 11.0 0.015 15.5 0.1 13.2 13 0 0 13 13 13 10 HEAT repeat HEAT_2 PF13646.6 KZN91951.1 - 6.8e-36 122.5 5.1 3.7e-11 43.3 0.0 7.7 4 2 5 9 9 9 8 HEAT repeats HEAT_EZ PF13513.6 KZN91951.1 - 2.4e-13 50.2 8.7 0.00098 19.6 0.0 8.6 6 3 4 10 10 10 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KZN91951.1 - 1.2e-11 45.1 3.6 0.0011 19.5 0.1 7.4 5 2 4 9 9 9 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KZN91951.1 - 5.9e-09 36.2 12.4 0.01 15.9 0.2 5.5 5 1 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KZN91951.1 - 1.5e-06 27.1 11.3 0.00073 18.2 1.3 4.7 3 1 0 4 4 4 3 Adaptin N terminal region RTP1_C1 PF10363.9 KZN91951.1 - 2.4e-06 27.7 6.3 0.27 11.4 0.2 4.9 4 1 1 5 5 5 3 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KZN91951.1 - 0.00093 18.8 2.2 7.1 6.1 0.0 4.4 3 2 2 5 5 5 2 CLASP N terminal Proteasom_PSMB PF10508.9 KZN91951.1 - 0.0029 16.2 3.4 0.48 8.9 0.0 2.6 2 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit TetR_C_16 PF17920.1 KZN91951.1 - 0.041 14.1 0.3 22 5.4 0.1 3.3 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain IFRD PF05004.13 KZN91951.1 - 0.16 11.1 0.7 3.2 6.8 0.0 3.2 2 1 0 3 3 3 0 Interferon-related developmental regulator (IFRD) Arm PF00514.23 KZN91951.1 - 0.23 11.6 9.9 3.7 7.7 0.0 6.0 9 0 0 9 9 7 0 Armadillo/beta-catenin-like repeat API5 PF05918.11 KZN91951.1 - 4.3 6.0 6.1 0.95 8.2 0.4 2.9 3 2 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) tRNA_synthFbeta PF17759.1 KZN91952.1 - 1.1e-49 168.8 0.0 1.6e-49 168.2 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KZN91952.1 - 3e-34 117.1 0.2 1e-32 112.2 0.1 2.5 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KZN91952.1 - 9.4e-25 87.3 0.0 2.2e-24 86.1 0.0 1.6 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KZN91952.1 - 1.3e-19 70.3 0.0 5e-17 62.0 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain CDO_I PF05995.12 KZN91953.1 - 1.5e-43 148.0 0.0 2e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 KZN91953.1 - 0.00056 19.4 0.0 0.00078 18.9 0.0 1.2 1 0 0 1 1 1 1 PCO_ADO MMR_HSR1_Xtn PF16897.5 KZN91954.1 - 1.2e-38 131.4 0.8 3.4e-38 129.9 0.2 2.0 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KZN91954.1 - 2.3e-22 79.2 0.1 5.8e-22 77.9 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 KZN91954.1 - 1.1e-19 70.2 0.1 2.6e-19 69.0 0.1 1.7 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KZN91954.1 - 7.8e-11 41.7 0.2 3.5e-10 39.6 0.1 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KZN91954.1 - 2.2e-05 24.6 0.1 0.15 12.1 0.0 2.4 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 KZN91954.1 - 0.00032 20.3 0.1 4.8 6.7 0.0 3.9 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KZN91954.1 - 0.0028 17.6 0.6 0.26 11.2 0.0 3.1 2 1 1 3 3 3 1 RsgA GTPase MeaB PF03308.16 KZN91954.1 - 0.0094 15.0 0.2 0.024 13.6 0.1 1.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 KZN91954.1 - 0.016 14.5 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 AIG1 family Arf PF00025.21 KZN91954.1 - 0.035 13.6 0.2 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family HTH_Tnp_Tc5 PF03221.16 KZN91955.1 - 5.2e-14 52.0 0.0 9.4e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KZN91955.1 - 5.6e-05 22.7 0.1 0.00012 21.7 0.1 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 KZN91955.1 - 0.00051 19.8 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.22 KZN91955.1 - 0.012 15.5 0.1 0.098 12.6 0.0 2.5 3 0 0 3 3 3 0 MarR family HTH_Tnp_4 PF13613.6 KZN91955.1 - 0.037 13.8 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_IclR PF09339.10 KZN91955.1 - 0.11 12.3 0.1 6.5 6.6 0.0 2.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_10 PF04967.12 KZN91955.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain HTH_Crp_2 PF13545.6 KZN91955.1 - 0.17 11.9 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_37 PF13744.6 KZN91955.1 - 0.22 11.5 0.0 4.8 7.2 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PXA PF02194.15 KZN91956.1 - 5.5e-48 163.4 0.0 7.2e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 PXA domain Tho1_MOS11_C PF18592.1 KZN91956.1 - 0.077 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Tho1/MOS11 C-terminal domain IU_nuc_hydro PF01156.19 KZN91957.1 - 1.5e-43 149.5 0.0 1.7e-43 149.3 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase HAMP_N3 PF18575.1 KZN91957.1 - 0.021 14.4 0.1 0.042 13.4 0.1 1.4 1 0 0 1 1 1 0 HAMP N-terminal domain 3 Vac_ImportDeg PF09783.9 KZN91958.1 - 4.2e-40 137.2 0.0 1.4e-39 135.5 0.0 1.7 2 0 0 2 2 2 1 Vacuolar import and degradation protein Amino_oxidase PF01593.24 KZN91959.1 - 1.1e-71 242.5 0.0 3.2e-70 237.7 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KZN91959.1 - 1.9e-08 34.4 0.1 4.8e-08 33.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KZN91959.1 - 2.7e-05 23.6 0.0 0.019 14.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KZN91959.1 - 3.8e-05 24.2 0.5 0.11 13.1 0.1 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KZN91959.1 - 0.0002 20.7 0.2 0.037 13.3 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KZN91959.1 - 0.0051 16.1 0.1 0.0088 15.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KZN91959.1 - 0.0081 16.2 0.2 5.2 7.0 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 KZN91959.1 - 0.0099 15.5 3.1 0.034 13.7 0.4 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KZN91959.1 - 0.01 15.1 0.8 0.068 12.4 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KZN91959.1 - 0.014 14.7 0.6 0.026 13.8 0.6 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KZN91959.1 - 0.14 11.5 0.3 0.41 9.9 0.2 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 KZN91959.1 - 0.2 10.7 0.1 0.32 10.0 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 KZN91959.1 - 0.23 10.1 0.3 2.3 6.8 0.3 2.1 2 0 0 2 2 2 0 HI0933-like protein Glyco_hydro_43 PF04616.14 KZN91960.1 - 0.0025 17.2 5.5 0.0042 16.4 5.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 MFS_1 PF07690.16 KZN91961.1 - 1.9e-37 129.0 35.1 2.2e-37 128.8 35.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN91961.1 - 2.5e-10 39.8 14.9 8.6e-10 38.0 14.9 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter CRPA PF05745.11 KZN91961.1 - 1.3 9.1 3.7 14 5.7 0.1 2.8 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Zn_clus PF00172.18 KZN91962.1 - 1.7e-10 40.9 10.6 2.7e-10 40.2 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NMO PF03060.15 KZN91963.1 - 5.5e-24 85.2 2.0 2.5e-15 56.7 0.1 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 KZN91963.1 - 3.3e-09 36.2 0.2 0.00018 20.6 0.1 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KZN91963.1 - 3e-05 23.2 3.6 3.4e-05 23.0 2.9 1.4 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KZN91963.1 - 0.0056 15.9 0.1 0.01 15.0 0.1 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 KZN91963.1 - 0.095 11.9 0.4 0.15 11.2 0.4 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Antifungal_pept PF11410.8 KZN91964.1 - 0.013 15.4 4.7 0.013 15.4 4.7 2.7 2 0 0 2 2 2 0 Antifungal peptide p450 PF00067.22 KZN91965.1 - 4.1e-69 233.5 0.0 5.3e-69 233.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 KZN91966.1 - 0.081 13.1 14.3 0.13 12.4 14.3 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L7Ae PF01248.26 KZN91967.1 - 7.1e-27 93.0 0.6 8.8e-27 92.7 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 KZN91967.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain Ank_2 PF12796.7 KZN91968.1 - 2.1e-22 79.5 0.3 2.9e-12 47.0 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KZN91968.1 - 4.6e-17 61.9 1.2 1e-07 32.0 0.0 5.0 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KZN91968.1 - 6.7e-17 61.6 0.2 8.3e-07 29.4 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KZN91968.1 - 5.3e-13 48.8 1.5 0.0026 18.2 0.0 5.4 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 KZN91968.1 - 2.3e-11 42.9 0.3 0.0056 17.1 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Steroid_dh PF02544.16 KZN91969.1 - 4.4e-12 46.2 0.6 4.4e-12 46.2 0.6 1.8 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase BRI3BP PF14965.6 KZN91969.1 - 0.005 16.4 0.9 0.005 16.4 0.9 2.6 3 0 0 3 3 3 1 Negative regulator of p53/TP53 LGT PF01790.18 KZN91969.1 - 0.018 14.3 0.4 0.03 13.6 0.4 1.3 1 0 0 1 1 1 0 Prolipoprotein diacylglyceryl transferase 2OG-FeII_Oxy_2 PF13532.6 KZN91970.1 - 2.2e-09 37.8 0.0 7.1e-09 36.1 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rotamase_3 PF13616.6 KZN91971.1 - 5.8e-18 65.5 1.9 1.1e-17 64.6 0.8 1.9 1 1 1 2 2 2 1 PPIC-type PPIASE domain Rotamase PF00639.21 KZN91971.1 - 7e-15 55.8 0.4 1.3e-14 54.9 0.1 1.6 1 1 1 2 2 2 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KZN91971.1 - 7.4e-05 23.6 4.3 9.1e-05 23.3 0.1 2.0 1 1 1 2 2 2 1 PPIC-type PPIASE domain UAA PF08449.11 KZN91972.1 - 1.4e-43 149.3 9.1 5.3e-43 147.3 9.1 1.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KZN91972.1 - 2.7e-06 27.6 28.5 0.0004 20.6 9.7 3.6 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.15 KZN91972.1 - 1.2e-05 24.7 0.8 0.054 12.7 0.1 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter DUF5090 PF17009.5 KZN91972.1 - 2.3 8.1 7.8 0.68 9.9 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) Sen15 PF09631.10 KZN91973.1 - 1.9e-11 44.1 0.0 1.9e-09 37.7 0.0 2.3 1 1 0 1 1 1 1 Sen15 protein VASt PF16016.5 KZN91974.1 - 2.2e-34 119.1 0.2 5.9e-34 117.7 0.2 1.7 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 KZN91974.1 - 6.3e-15 55.5 0.2 6.3e-15 55.5 0.2 2.0 2 0 0 2 2 2 1 BAR domain of APPL family PH PF00169.29 KZN91974.1 - 2.8e-10 40.6 0.0 1.2e-09 38.6 0.0 2.2 1 0 0 1 1 1 1 PH domain GRAM PF02893.20 KZN91974.1 - 0.01 15.7 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 0 GRAM domain BAR PF03114.18 KZN91974.1 - 0.018 14.7 0.2 0.035 13.7 0.2 1.4 1 0 0 1 1 1 0 BAR domain Kri1_C PF12936.7 KZN91975.1 - 1.8e-32 111.4 1.0 1.8e-32 111.4 1.0 3.6 3 1 0 3 3 3 1 KRI1-like family C-terminal Kri1 PF05178.12 KZN91975.1 - 3.9e-28 98.0 16.2 3.9e-28 98.0 16.2 5.7 7 1 0 7 7 7 1 KRI1-like family LicD PF04991.13 KZN91975.1 - 0.0021 18.2 3.7 0.0021 18.2 3.7 2.6 2 1 0 2 2 2 1 LicD family TMPIT PF07851.13 KZN91975.1 - 0.88 8.8 4.2 2.2 7.4 4.2 1.6 1 0 0 1 1 1 0 TMPIT-like protein Spem1 PF15670.5 KZN91975.1 - 1.6 8.2 6.4 5 6.6 1.7 2.7 2 0 0 2 2 2 0 Spermatid maturation protein 1 Mito_carr PF00153.27 KZN91976.1 - 6.6e-67 221.5 6.0 2.4e-24 85.1 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Stb3 PF10330.9 KZN91978.1 - 3.2e-40 136.1 0.0 4.8e-40 135.5 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein RunxI PF08504.11 KZN91978.1 - 0.1 13.3 0.6 0.28 11.9 0.6 1.7 1 0 0 1 1 1 0 Runx inhibition domain COesterase PF00135.28 KZN91979.1 - 2e-86 290.9 0.1 1.1e-85 288.5 0.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KZN91979.1 - 1.3e-11 44.8 0.2 6.9e-11 42.4 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KZN91979.1 - 0.00029 20.4 0.6 0.00059 19.4 0.2 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family TSP_C PF05735.12 KZN91979.1 - 0.057 13.3 0.2 0.1 12.5 0.2 1.3 1 0 0 1 1 1 0 Thrombospondin C-terminal region SDA1 PF05285.12 KZN91980.1 - 0.028 13.9 0.1 0.038 13.4 0.1 1.1 1 0 0 1 1 1 0 SDA1 Ribosomal_S19e PF01090.19 KZN91981.1 - 8.2e-58 194.0 0.1 9.3e-58 193.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Abhydrolase_1 PF00561.20 KZN91982.1 - 1.2e-17 64.4 0.0 5.1e-17 62.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KZN91982.1 - 1.6e-17 64.8 2.6 3.7e-17 63.7 2.6 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KZN91982.1 - 1.5e-12 47.3 0.1 3.2e-09 36.4 0.0 3.1 3 0 0 3 3 3 2 Serine aminopeptidase, S33 DSPc PF00782.20 KZN91982.1 - 9.1e-09 35.2 0.0 2.1e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Thioesterase PF00975.20 KZN91982.1 - 2.7e-05 24.4 0.0 4.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.25 KZN91982.1 - 0.00014 21.7 0.1 0.0049 16.7 0.1 2.4 1 1 0 1 1 1 1 Lipase (class 3) Ser_hydrolase PF06821.13 KZN91982.1 - 0.00043 20.2 0.5 0.0033 17.3 0.0 2.4 3 0 0 3 3 3 1 Serine hydrolase PTPlike_phytase PF14566.6 KZN91982.1 - 0.0015 18.7 0.0 0.0025 17.9 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate PGAP1 PF07819.13 KZN91982.1 - 0.0018 18.0 0.0 0.045 13.5 0.0 2.4 2 0 0 2 2 2 1 PGAP1-like protein DUF1749 PF08538.10 KZN91982.1 - 0.0021 17.2 0.0 0.14 11.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) FSH1 PF03959.13 KZN91982.1 - 0.021 14.5 0.0 0.84 9.3 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase (FSH1) LCAT PF02450.15 KZN91982.1 - 0.038 13.1 0.0 0.077 12.1 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Y_phosphatase PF00102.27 KZN91982.1 - 0.049 13.2 0.0 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein-tyrosine phosphatase Abhydrolase_4 PF08386.10 KZN91982.1 - 0.056 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein LIDHydrolase PF10230.9 KZN91982.1 - 0.072 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Chlorophyllase2 PF12740.7 KZN91982.1 - 0.12 11.3 0.0 0.32 9.9 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase enzyme HTH_Tnp_Tc5 PF03221.16 KZN91983.1 - 3.5e-12 46.1 0.1 1.2e-11 44.4 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_32 PF13565.6 KZN91983.1 - 0.011 16.3 4.0 0.043 14.4 0.1 3.1 2 1 0 2 2 2 0 Homeodomain-like domain DUF755 PF05501.11 KZN91983.1 - 0.1 12.9 4.6 0.24 11.7 4.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) ILVD_EDD PF00920.21 KZN91984.1 - 1.3e-210 700.4 0.6 1.6e-210 700.2 0.6 1.0 1 0 0 1 1 1 1 Dehydratase family DUF1772 PF08592.11 KZN91985.1 - 8.7e-29 100.6 0.2 9.8e-29 100.4 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Pex2_Pex12 PF04757.14 KZN91986.1 - 6.9e-36 123.9 0.1 9.9e-36 123.4 0.1 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 KZN91986.1 - 0.0012 18.9 5.5 0.0023 18.0 5.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KZN91986.1 - 0.063 13.3 3.6 0.22 11.6 3.6 1.9 1 1 0 1 1 1 0 RING-type zinc-finger HNH_2 PF13391.6 KZN91987.1 - 1.4e-17 63.6 0.0 3.4e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease Phosphoesterase PF04185.14 KZN91988.1 - 2.7e-33 115.7 5.4 1.7e-32 113.0 5.4 2.0 1 1 0 1 1 1 1 Phosphoesterase family HIF-1a_CTAD PF08778.10 KZN91988.1 - 0.075 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 HIF-1 alpha C terminal transactivation domain IBN_N PF03810.19 KZN91989.1 - 6.6e-16 58.0 0.0 3.7e-15 55.6 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KZN91989.1 - 2.8e-05 24.2 2.0 0.00048 20.2 0.0 2.9 3 0 0 3 3 3 1 Exportin 1-like protein PAGK PF15284.6 KZN91989.1 - 0.46 10.4 1.7 25 4.9 0.1 3.4 3 0 0 3 3 3 0 Phage-encoded virulence factor Cellulase PF00150.18 KZN91990.1 - 2.9e-20 72.8 3.5 9.1e-20 71.2 3.5 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RPAP1_N PF08621.10 KZN91990.1 - 0.13 12.0 0.3 0.24 11.2 0.3 1.3 1 0 0 1 1 1 0 RPAP1-like, N-terminal CN_hydrolase PF00795.22 KZN91991.1 - 1.9e-36 125.8 0.0 2.2e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Glyco_hydro_2_C PF02836.17 KZN91992.1 - 1.2e-14 54.1 0.1 1.9e-13 50.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KZN91992.1 - 5.9e-13 49.1 0.1 2.8e-12 46.9 0.1 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KZN91992.1 - 3.4e-12 47.0 1.5 4.9e-12 46.5 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Protoglobin PF11563.8 KZN91993.1 - 3.5e-56 189.5 0.5 4.4e-56 189.1 0.5 1.1 1 0 0 1 1 1 1 Protoglobin Aldedh PF00171.22 KZN91994.1 - 2.9e-137 458.0 0.6 3.6e-137 457.7 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KZN91994.1 - 0.0011 18.1 0.1 0.011 14.8 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) GPI-anchored PF10342.9 KZN91995.1 - 1e-23 83.8 0.1 1e-23 83.8 0.1 2.1 3 0 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Fungal_trans PF04082.18 KZN91996.1 - 9.3e-12 44.5 0.9 9.3e-12 44.5 0.9 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain bZIP_2 PF07716.15 KZN91997.1 - 0.086 12.9 12.0 0.15 12.2 12.0 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Remorin_C PF03763.13 KZN91997.1 - 0.095 12.6 7.9 0.16 11.8 7.9 1.3 1 0 0 1 1 1 0 Remorin, C-terminal region COG2 PF06148.11 KZN91997.1 - 0.1 12.7 1.5 0.15 12.2 1.5 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 UPF0449 PF15136.6 KZN91997.1 - 5.6 7.5 13.1 0.058 13.9 3.8 2.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 SGL PF08450.12 KZN91998.1 - 4.4e-75 252.4 0.0 5.2e-75 252.2 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Aldedh PF00171.22 KZN91999.1 - 2.7e-183 609.7 0.1 3e-183 609.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KZN91999.1 - 0.00051 19.6 0.0 0.00091 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) IPI_T4 PF11634.8 KZN91999.1 - 0.13 12.3 0.0 11 6.1 0.0 2.6 2 0 0 2 2 2 0 Nuclease inhibitor from bacteriophage T4 DUF5133 PF17196.4 KZN91999.1 - 1.1 9.5 3.6 6.7 7.0 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF5133) EVE PF01878.18 KZN92000.1 - 1.7e-49 167.6 0.2 2.5e-49 167.0 0.2 1.3 1 0 0 1 1 1 1 EVE domain AT_hook PF02178.19 KZN92000.1 - 9.8e-06 24.9 45.7 0.027 14.3 2.0 5.3 5 0 0 5 5 5 4 AT hook motif RFX5_DNA_bdg PF14621.6 KZN92000.1 - 0.43 10.3 29.6 0.18 11.5 1.6 4.1 1 1 3 4 4 4 0 RFX5 DNA-binding domain MSP1a PF11670.8 KZN92000.1 - 0.71 9.1 1.8 1.1 8.5 1.8 1.2 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) AhpC-TSA PF00578.21 KZN92001.1 - 1.4e-31 109.0 0.0 1.9e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KZN92001.1 - 7.7e-15 54.9 0.0 1e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KZN92001.1 - 4.3e-12 45.7 0.1 7.2e-12 45.0 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Kelch_4 PF13418.6 KZN92002.1 - 2.9e-18 65.6 0.1 1.2e-05 25.2 0.0 5.2 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.6 KZN92002.1 - 1.6e-13 50.6 4.0 4.7e-09 36.3 0.0 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KZN92002.1 - 2.8e-13 49.5 3.5 8.2e-05 22.5 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 KZN92002.1 - 6.4e-12 44.9 0.1 0.0034 16.9 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 KZN92002.1 - 5.5e-11 42.3 4.6 0.015 15.6 0.0 5.5 4 1 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 KZN92002.1 - 6.2e-10 38.7 0.1 0.001 19.0 0.0 4.4 3 1 0 3 3 3 3 Kelch motif BTB PF00651.31 KZN92002.1 - 0.2 11.9 0.0 1.6 9.0 0.1 2.1 2 0 0 2 2 2 0 BTB/POZ domain Ribophorin_II PF05817.14 KZN92005.1 - 4.7e-32 111.4 0.0 5.8e-32 111.0 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II FMN_bind_2 PF04299.12 KZN92007.1 - 2.3e-59 199.8 0.0 2.8e-59 199.6 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Sulfatase PF00884.23 KZN92008.1 - 3.2e-20 72.7 1.4 5.3e-20 72.0 1.4 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KZN92008.1 - 4.4e-07 29.8 0.1 7.4e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KZN92008.1 - 0.0003 19.5 0.0 0.00045 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Dam PF05869.11 KZN92008.1 - 0.082 12.5 0.1 0.2 11.2 0.1 1.6 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) Pkinase_Tyr PF07714.17 KZN92009.1 - 1.4e-13 50.8 0.0 8.9e-13 48.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KZN92009.1 - 6.1e-13 48.7 0.0 4.8e-12 45.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 KZN92009.1 - 0.0093 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KZN92009.1 - 0.013 15.1 0.1 0.021 14.4 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Kinase-PolyVal PF18762.1 KZN92009.1 - 0.05 13.6 0.0 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins Kdo PF06293.14 KZN92009.1 - 0.089 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family adh_short_C2 PF13561.6 KZN92010.1 - 2e-57 194.4 0.3 2.3e-57 194.2 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN92010.1 - 1.3e-47 161.8 1.7 1.7e-47 161.4 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN92010.1 - 1.3e-14 54.5 0.5 1.8e-14 54.1 0.5 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KZN92010.1 - 1.1e-05 25.1 0.1 1.4e-05 24.6 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KZN92010.1 - 0.018 14.5 0.2 0.059 12.8 0.0 1.9 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_7 PF13241.6 KZN92010.1 - 0.17 12.3 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding PTR2 PF00854.21 KZN92011.1 - 1.1e-73 248.4 6.1 1.5e-73 247.9 6.1 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 KZN92011.1 - 1.7e-08 33.8 21.0 2.8e-07 29.8 20.2 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF21 PF01595.20 KZN92011.1 - 0.64 9.7 10.6 4 7.1 0.7 3.5 3 0 0 3 3 3 0 Cyclin M transmembrane N-terminal domain PLA2_B PF01735.18 KZN92012.1 - 3.4e-211 701.9 1.0 4e-211 701.7 1.0 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain CAF1A PF12253.8 KZN92013.1 - 0.0022 18.1 1.3 0.0022 18.1 1.3 4.8 5 0 0 5 5 5 1 Chromatin assembly factor 1 subunit A DUF3123 PF11321.8 KZN92013.1 - 0.12 13.1 0.2 0.12 13.1 0.2 5.7 4 1 2 6 6 6 0 Protein of unknown function (DUF3123) DUF5583 PF17821.1 KZN92013.1 - 0.13 12.2 0.2 1 9.3 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5583) DAHP_synth_2 PF01474.16 KZN92014.1 - 3.1e-199 662.0 0.0 3.5e-199 661.8 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family BES1_N PF05687.13 KZN92015.1 - 0.19 12.1 15.3 0.082 13.3 12.9 1.7 2 0 0 2 2 2 0 BES1/BZR1 plant transcription factor, N-terminal GREB1 PF15782.5 KZN92015.1 - 0.24 8.5 6.0 0.23 8.5 6.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAP1 PF08601.10 KZN92015.1 - 1.4 8.6 19.6 1.9 8.1 19.6 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 SPX PF03105.19 KZN92015.1 - 2.4 8.0 12.2 3 7.6 12.2 1.1 1 0 0 1 1 1 0 SPX domain DUF4653 PF15546.6 KZN92015.1 - 4.3 6.9 12.0 6.2 6.4 12.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) DUF1635 PF07795.11 KZN92015.1 - 4.8 7.0 8.5 7.8 6.3 8.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) MFS_1 PF07690.16 KZN92018.1 - 1.3e-28 100.0 24.1 2.3e-28 99.2 24.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily ATG11 PF10377.9 KZN92019.1 - 0.036 14.1 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 Autophagy-related protein 11 Aldose_epim PF01263.20 KZN92020.1 - 1.9e-38 132.5 0.1 2.4e-38 132.2 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase AA_permease_2 PF13520.6 KZN92021.1 - 3.3e-48 164.6 48.5 4e-48 164.3 48.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN92021.1 - 1.5e-17 63.3 39.0 2.2e-17 62.8 39.0 1.1 1 0 0 1 1 1 1 Amino acid permease Bac_thur_toxin PF01338.18 KZN92022.1 - 0.063 12.7 0.2 0.096 12.1 0.2 1.3 1 0 0 1 1 1 0 Bacillus thuringiensis toxin SNF PF00209.18 KZN92023.1 - 1.4e-70 238.5 37.5 8.5e-45 153.4 16.6 2.8 3 0 0 3 3 3 2 Sodium:neurotransmitter symporter family DUF3810 PF12725.7 KZN92023.1 - 0.065 12.6 0.5 0.15 11.4 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Aldo_ket_red PF00248.21 KZN92024.1 - 9.7e-49 166.1 0.0 1.2e-48 165.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Seadorna_Vp10 PF07322.11 KZN92024.1 - 0.017 14.5 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus Vp10 Rif1_N PF12231.8 KZN92025.1 - 1.3e-143 478.5 0.2 2e-143 478.0 0.2 1.3 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Ric8 PF10165.9 KZN92026.1 - 9.3e-116 387.6 0.0 1.1e-115 387.3 0.0 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Cnd3 PF12719.7 KZN92026.1 - 0.014 14.6 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain Polysacc_synt_4 PF04669.13 KZN92027.1 - 3.3e-18 65.9 1.3 9.5e-17 61.2 1.3 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis ABC_membrane PF00664.23 KZN92028.1 - 6.6e-84 281.8 24.9 5.7e-43 147.5 6.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KZN92028.1 - 5.2e-61 205.1 0.0 6.1e-29 101.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KZN92028.1 - 3.3e-19 69.2 0.4 1.9e-08 34.1 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KZN92028.1 - 3.7e-10 40.1 0.9 0.13 12.0 0.0 4.5 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KZN92028.1 - 3.3e-08 33.2 0.7 0.012 15.3 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KZN92028.1 - 3e-07 30.8 0.5 0.0079 16.5 0.1 3.5 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.6 KZN92028.1 - 1.4e-06 28.8 0.5 0.097 13.0 0.4 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KZN92028.1 - 2.2e-06 27.4 0.1 0.22 11.0 0.0 3.7 4 0 0 4 4 4 2 AAA domain RsgA_GTPase PF03193.16 KZN92028.1 - 5.6e-06 26.4 0.5 0.11 12.5 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase AAA_33 PF13671.6 KZN92028.1 - 0.00022 21.4 0.2 0.51 10.5 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KZN92028.1 - 0.00023 21.0 0.1 0.36 10.5 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 KZN92028.1 - 0.00051 20.6 0.2 0.49 10.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KZN92028.1 - 0.00057 19.9 0.1 1.7 8.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) DUF87 PF01935.17 KZN92028.1 - 0.00072 19.7 0.5 1 9.4 0.0 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain DUF3987 PF13148.6 KZN92028.1 - 0.0038 16.3 0.1 1.9 7.4 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) MMR_HSR1 PF01926.23 KZN92028.1 - 0.0061 16.6 0.5 3.5 7.8 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 KZN92028.1 - 0.0076 16.6 0.0 4.4 7.8 0.0 3.0 3 0 0 3 3 2 1 RNA helicase ABC_ATPase PF09818.9 KZN92028.1 - 0.01 14.7 1.6 0.31 9.8 0.1 3.2 4 1 0 4 4 4 0 Predicted ATPase of the ABC class SbcCD_C PF13558.6 KZN92028.1 - 0.012 15.9 0.0 11 6.3 0.0 3.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KZN92028.1 - 0.016 15.8 0.3 2.1 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KZN92028.1 - 0.016 15.1 0.2 2.5 8.0 0.1 2.7 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 KZN92028.1 - 0.028 14.1 0.6 19 4.9 0.1 3.2 3 0 0 3 3 3 0 AAA domain APS_kinase PF01583.20 KZN92028.1 - 0.028 14.3 0.1 9.1 6.2 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase IstB_IS21 PF01695.17 KZN92028.1 - 0.031 14.0 0.3 28 4.4 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 KZN92028.1 - 0.043 13.2 0.0 7.6 5.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.6 KZN92028.1 - 0.052 13.3 0.4 6.9 6.3 0.0 3.3 4 0 0 4 4 4 0 AAA domain Sigma54_activat PF00158.26 KZN92028.1 - 0.062 13.0 0.0 10 5.8 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_13 PF13166.6 KZN92028.1 - 0.093 11.4 0.1 6.5 5.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain ATPase PF06745.13 KZN92028.1 - 0.14 11.5 6.4 4.7 6.5 0.1 3.9 5 0 0 5 5 5 0 KaiC Zeta_toxin PF06414.12 KZN92028.1 - 0.14 11.4 0.1 18 4.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_10 PF12846.7 KZN92028.1 - 0.2 10.6 0.1 8.1 5.3 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain CbiA PF01656.23 KZN92028.1 - 0.22 11.6 1.9 5.8 7.0 0.1 2.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Abhydrolase_6 PF12697.7 KZN92029.1 - 1.6e-14 55.1 1.7 1.8e-14 54.9 1.7 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Glyco_hydro_64 PF16483.5 KZN92030.1 - 1.1e-138 462.6 4.6 1.2e-138 462.4 4.6 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase SWM_repeat PF13753.6 KZN92030.1 - 1.1 9.5 0.0 1.1 9.5 0.0 2.6 2 1 0 3 3 3 0 Putative flagellar system-associated repeat RSN1_TM PF13967.6 KZN92031.1 - 0.09 12.5 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport DUF2207 PF09972.9 KZN92031.1 - 0.1 11.4 0.1 0.17 10.6 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Methyltransf_2 PF00891.18 KZN92032.1 - 2.2e-20 72.9 0.0 8.3e-20 71.0 0.0 2.0 1 1 0 1 1 1 1 O-methyltransferase domain DUF4082 PF13313.6 KZN92032.1 - 0.091 12.8 0.2 0.17 11.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) Peptidase_M24 PF00557.24 KZN92032.1 - 0.11 12.2 0.0 4.5 6.9 0.0 2.4 1 1 0 2 2 2 0 Metallopeptidase family M24 Gemini_AL1_M PF08283.11 KZN92032.1 - 0.15 12.2 0.0 0.95 9.6 0.0 2.2 2 0 0 2 2 2 0 Geminivirus rep protein central domain Zn_clus PF00172.18 KZN92033.1 - 5.8e-10 39.1 7.4 9.7e-10 38.4 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN92033.1 - 0.00018 20.7 0.1 0.0003 19.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain But2 PF09792.9 KZN92035.1 - 4.4e-54 182.7 1.2 4.4e-54 182.7 1.2 1.8 2 0 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF2568 PF10823.8 KZN92036.1 - 0.062 13.6 7.4 0.089 13.1 4.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2568) HemY_N PF07219.13 KZN92036.1 - 5 7.4 7.1 20 5.4 2.0 2.7 2 1 1 3 3 3 0 HemY protein N-terminus Acetyltransf_3 PF13302.7 KZN92037.1 - 3.8e-35 121.6 0.0 4.8e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KZN92037.1 - 5.5e-05 23.4 0.0 0.00064 19.9 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family DAO PF01266.24 KZN92038.1 - 6.1e-42 144.5 0.0 6.9e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KZN92038.1 - 0.0038 16.4 5.7 0.055 12.6 5.7 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KZN92038.1 - 0.0041 16.4 0.0 0.007 15.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KZN92038.1 - 0.011 15.6 0.1 0.019 14.8 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 KZN92038.1 - 0.013 14.8 1.0 0.024 14.0 1.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 KZN92038.1 - 0.048 12.7 2.5 0.16 11.0 0.6 2.4 2 1 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KZN92038.1 - 0.072 13.3 0.2 0.15 12.3 0.2 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KZN92038.1 - 0.089 11.5 1.6 5.9 5.5 0.2 2.2 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.14 KZN92038.1 - 0.13 11.5 0.5 0.39 9.9 0.5 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_S2 PF00318.20 KZN92039.1 - 9.4e-66 221.1 0.1 1.6e-64 217.1 0.1 2.1 1 1 0 1 1 1 1 Ribosomal protein S2 BBE PF08031.12 KZN92039.1 - 0.083 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like Rick_17kDa_Anti PF05433.15 KZN92040.1 - 6.6e-06 25.9 13.6 1.4e-05 24.9 13.6 1.6 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 KZN92040.1 - 0.03 14.3 13.1 0.074 13.1 13.1 1.7 1 0 0 1 1 1 0 Glycine zipper Transgly_assoc PF04226.13 KZN92040.1 - 0.71 10.2 12.3 1.2 9.4 12.3 1.4 1 0 0 1 1 1 0 Transglycosylase associated protein PT-VENN PF04829.13 KZN92040.1 - 1.3 9.2 5.0 2 8.5 5.0 1.3 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Mucin-like PF16058.5 KZN92040.1 - 1.4 9.0 31.4 1.1 9.4 25.2 3.0 2 1 0 2 2 2 0 Mucin-like TatD_DNase PF01026.21 KZN92041.1 - 0.02 14.3 0.0 0.027 13.8 0.0 1.1 1 0 0 1 1 1 0 TatD related DNase SURF6 PF04935.12 KZN92042.1 - 1.3e-49 168.7 32.4 1.3e-49 168.7 32.4 4.2 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.6 KZN92042.1 - 1.2e-17 64.2 1.1 1.2e-17 64.2 1.1 8.7 7 2 0 7 7 7 1 60S ribosome biogenesis protein Rrp14 Fer4 PF00037.27 KZN92043.1 - 3.8e-14 51.8 15.9 3.5e-08 32.9 4.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KZN92043.1 - 4.7e-13 49.5 10.5 7.3e-13 48.9 10.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KZN92043.1 - 1.3e-10 42.0 8.3 1.5e-05 25.8 0.7 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 KZN92043.1 - 2.2e-10 40.5 21.8 3.8e-07 30.1 12.5 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KZN92043.1 - 7.8e-10 38.8 21.1 5.1e-08 32.9 10.8 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KZN92043.1 - 1.4e-09 37.9 5.9 0.00011 22.2 0.4 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KZN92043.1 - 8.3e-09 35.8 2.8 0.0002 21.8 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KZN92043.1 - 1.6e-06 27.9 17.5 0.00038 20.4 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KZN92043.1 - 4.8e-06 26.3 12.5 0.01 15.9 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KZN92043.1 - 1.5e-05 25.2 11.0 0.00028 21.1 1.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KZN92043.1 - 8.8e-05 23.0 11.9 0.016 15.7 1.9 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 KZN92043.1 - 0.0095 16.1 5.4 0.69 10.2 0.2 2.2 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_18 PF13746.6 KZN92043.1 - 0.037 14.2 8.9 1.1 9.4 1.5 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 KZN92043.1 - 0.042 14.4 15.3 0.71 10.5 4.3 2.6 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 KZN92043.1 - 0.064 14.2 15.7 0.11 13.4 3.5 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 KZN92043.1 - 0.093 12.9 5.9 0.38 10.9 0.6 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 KZN92043.1 - 0.25 12.2 11.5 1.9 9.4 1.7 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain DUF4451 PF14616.6 KZN92043.1 - 0.83 9.9 4.2 4.9 7.4 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) PP-binding PF00550.25 KZN92044.1 - 6.5e-11 42.4 0.1 9e-11 42.0 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KZN92044.1 - 5.9e-06 26.4 0.1 7.5e-06 26.1 0.1 1.1 1 0 0 1 1 1 1 Acyl-carrier GPP34 PF05719.11 KZN92045.1 - 6.1e-66 222.3 0.1 7.8e-66 222.0 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) ADH_zinc_N_2 PF13602.6 KZN92046.1 - 7.9e-05 23.7 0.0 0.00019 22.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KZN92046.1 - 0.018 15.0 0.0 0.084 12.8 0.0 1.9 1 1 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DUF2183 PF09949.9 KZN92047.1 - 9.8e-35 118.9 0.1 2.1e-34 117.8 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 KZN92047.1 - 0.072 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) His_Phos_1 PF00300.22 KZN92048.1 - 4.3e-38 131.0 0.1 5.5e-38 130.6 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribo_biogen_C PF04034.13 KZN92049.1 - 4e-51 172.0 0.0 5.7e-51 171.5 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KZN92049.1 - 4.9e-11 42.3 1.0 4.9e-11 42.3 1.0 1.6 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI SDA1 PF05285.12 KZN92049.1 - 8 5.8 21.1 11 5.3 21.1 1.2 1 0 0 1 1 1 0 SDA1 VHS PF00790.19 KZN92050.1 - 3.8e-43 146.7 0.0 1.5e-42 144.8 0.0 2.0 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 KZN92050.1 - 1.1e-22 80.4 0.7 3e-22 79.0 0.7 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.14 KZN92050.1 - 3.1e-21 75.5 0.2 1e-20 73.8 0.2 2.0 1 0 0 1 1 1 1 GAT domain GGA_N-GAT PF18308.1 KZN92050.1 - 5.7e-08 32.2 0.4 3.6e-07 29.7 0.0 2.4 2 0 0 2 2 2 1 GGA N-GAT domain Mei5 PF10376.9 KZN92050.1 - 0.064 13.1 2.4 0.12 12.2 2.4 1.5 1 0 0 1 1 1 0 Double-strand recombination repair protein DUF349 PF03993.12 KZN92050.1 - 7.5 6.9 6.6 0.94 9.8 0.9 2.2 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) CBS PF00571.28 KZN92052.1 - 1.6e-19 70.1 4.9 2e-06 28.1 0.0 5.3 5 0 0 5 5 5 4 CBS domain Sugar_tr PF00083.24 KZN92053.1 - 0.012 14.6 0.9 0.012 14.5 0.9 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter Zn_clus PF00172.18 KZN92054.1 - 2e-09 37.4 9.4 3.4e-09 36.7 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YvfG PF09628.10 KZN92054.1 - 0.17 12.3 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 YvfG protein PhyH PF05721.13 KZN92055.1 - 6.8e-29 101.6 0.1 8.9e-29 101.3 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KZN92055.1 - 4.8e-05 23.7 0.0 0.00011 22.6 0.0 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 KZN92055.1 - 0.033 15.1 0.1 0.07 14.0 0.1 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily MOSC PF03473.17 KZN92056.1 - 1e-33 116.2 0.0 1.8e-33 115.3 0.0 1.5 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.19 KZN92056.1 - 3.9e-27 95.2 0.0 6.7e-27 94.4 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.16 KZN92056.1 - 5e-26 90.9 0.0 8.9e-26 90.1 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Mitoc_mL59 PF18126.1 KZN92057.1 - 5.8e-45 152.8 4.6 7.3e-45 152.4 4.6 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 TPR_14 PF13428.6 KZN92058.1 - 2.9e-05 24.5 7.2 0.61 11.0 0.0 7.4 6 2 2 8 8 8 1 Tetratricopeptide repeat Suf PF05843.14 KZN92058.1 - 0.00012 22.2 8.0 0.0056 16.7 0.5 3.2 3 0 0 3 3 3 3 Suppressor of forked protein (Suf) FAT PF02259.23 KZN92058.1 - 0.047 12.9 0.0 0.24 10.6 0.0 2.1 2 1 0 2 2 2 0 FAT domain DEAD PF00270.29 KZN92059.1 - 1.7e-47 161.5 0.0 1.5e-46 158.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KZN92059.1 - 1.2e-29 102.8 0.1 8.9e-29 100.1 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KZN92059.1 - 0.00055 20.0 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3334 PF11813.8 KZN92059.1 - 0.019 14.7 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) DUF2986 PF11661.8 KZN92059.1 - 0.02 15.4 3.0 0.08 13.5 3.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2986) ERAP1_C PF11838.8 KZN92060.1 - 2.8e-90 303.1 0.0 2.3e-88 296.8 0.0 2.4 2 0 0 2 2 2 2 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KZN92060.1 - 3.1e-84 281.9 0.5 4.7e-84 281.3 0.5 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KZN92060.1 - 8.1e-56 189.1 1.2 1.3e-55 188.5 1.2 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 KZN92060.1 - 0.006 16.6 0.1 0.012 15.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2808) AA_permease_2 PF13520.6 KZN92061.1 - 7.9e-92 308.3 38.5 9.7e-92 308.0 38.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN92061.1 - 3.2e-18 65.6 33.3 4.5e-18 65.1 33.3 1.2 1 0 0 1 1 1 1 Amino acid permease DUF3543 PF12063.8 KZN92062.1 - 1.2e-95 319.7 0.0 1.7e-95 319.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 KZN92062.1 - 2.4e-61 207.4 0.0 4.2e-61 206.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN92062.1 - 1.3e-42 145.9 0.0 2.2e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KZN92062.1 - 0.084 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Hepatitis_core PF00906.20 KZN92062.1 - 3.1 7.3 5.5 7.1 6.1 5.5 1.5 1 0 0 1 1 1 0 Hepatitis core antigen zf-C2H2 PF00096.26 KZN92064.1 - 4.4e-12 45.7 13.5 1.9e-06 28.0 0.4 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KZN92064.1 - 5e-08 33.1 10.0 0.0022 18.7 0.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KZN92064.1 - 8.3e-08 32.3 9.9 6.8e-07 29.4 4.1 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KZN92064.1 - 4e-05 23.8 4.9 0.01 16.1 0.5 2.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KZN92064.1 - 0.00016 21.6 9.2 0.0069 16.4 0.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KZN92064.1 - 0.00033 20.9 8.3 0.0067 16.8 0.3 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 KZN92064.1 - 0.0027 17.3 3.0 1.1 9.0 0.3 2.5 1 1 1 2 2 2 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-LYAR PF08790.11 KZN92064.1 - 0.13 12.2 1.7 15 5.6 0.1 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-BED PF02892.15 KZN92064.1 - 0.13 12.3 5.4 0.052 13.6 1.5 2.1 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_3rep PF18868.1 KZN92064.1 - 0.32 11.7 1.9 6.8 7.4 0.4 2.4 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 KZN92064.1 - 0.47 10.3 7.8 9 6.2 0.0 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KZN92064.1 - 0.48 10.8 3.5 7 7.0 0.4 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 KZN92064.1 - 0.61 10.6 7.0 77 3.8 7.0 2.6 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger PITH PF06201.13 KZN92065.1 - 1.8e-34 119.1 0.0 3e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 KZN92065.1 - 4.4e-27 94.1 0.0 8e-27 93.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KZN92065.1 - 3.2e-07 30.8 0.3 7e-06 26.5 0.3 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KZN92065.1 - 9.3e-06 25.9 0.0 0.0098 16.2 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 KZN92065.1 - 0.00013 21.4 0.1 0.0002 20.8 0.1 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 KZN92065.1 - 0.0002 21.1 0.0 0.00032 20.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KZN92065.1 - 0.0015 18.5 0.0 0.2 11.6 0.0 2.2 1 1 1 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 KZN92065.1 - 0.0063 16.2 0.2 0.21 11.3 0.0 2.2 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.6 KZN92065.1 - 0.048 13.9 0.0 0.15 12.2 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like HyaE PF07449.11 KZN92065.1 - 0.057 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE zf-CSL PF05207.13 KZN92066.1 - 1.3e-18 66.5 2.1 1.9e-18 65.9 2.1 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 KZN92066.1 - 6.2e-12 45.5 0.1 2.6e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 DnaJ domain peroxidase PF00141.23 KZN92067.1 - 1.7e-49 168.6 0.0 2.7e-49 167.9 0.0 1.2 1 0 0 1 1 1 1 Peroxidase ArfGap PF01412.18 KZN92068.1 - 5e-34 116.9 0.1 1.2e-33 115.7 0.1 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Glyco_transf_22 PF03901.17 KZN92069.1 - 2.9e-82 277.1 15.6 3.5e-82 276.9 15.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Aminotran_3 PF00202.21 KZN92070.1 - 4.6e-117 391.1 0.0 5.3e-117 390.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KZN92070.1 - 0.047 12.9 0.0 0.065 12.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II ABC_membrane PF00664.23 KZN92071.1 - 1.2e-53 182.5 39.5 3.5e-34 118.7 20.5 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KZN92071.1 - 1e-45 155.6 0.1 6.1e-25 88.3 0.0 3.0 3 0 0 3 3 2 2 ABC transporter MMR_HSR1 PF01926.23 KZN92071.1 - 2.3e-07 30.9 0.4 0.013 15.6 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 KZN92071.1 - 1.7e-06 27.7 1.6 0.084 12.3 0.6 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 KZN92071.1 - 3.1e-05 23.3 0.0 0.0044 16.3 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_21 PF13304.6 KZN92071.1 - 6.6e-05 22.9 1.5 0.14 11.9 0.1 3.5 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KZN92071.1 - 0.00012 22.1 0.1 0.2 11.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KZN92071.1 - 0.00016 22.1 0.5 0.47 10.8 0.0 3.3 2 1 1 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 KZN92071.1 - 0.00078 19.1 4.0 0.31 10.8 0.1 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain MeaB PF03308.16 KZN92071.1 - 0.0051 15.8 0.5 1.6 7.6 0.1 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 KZN92071.1 - 0.015 15.1 1.5 4 7.1 0.0 2.6 3 0 0 3 3 2 0 AAA ATPase domain AAA_23 PF13476.6 KZN92071.1 - 0.016 15.8 5.5 0.33 11.4 0.1 3.5 4 0 0 4 4 4 0 AAA domain AAA_22 PF13401.6 KZN92071.1 - 0.019 15.3 2.4 7.4 6.9 0.1 3.6 4 0 0 4 4 3 0 AAA domain Dynamin_N PF00350.23 KZN92071.1 - 0.021 14.9 5.4 0.25 11.4 0.0 2.9 3 0 0 3 3 2 0 Dynamin family AAA_18 PF13238.6 KZN92071.1 - 0.054 14.0 0.6 20 5.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 KZN92071.1 - 0.11 12.2 0.0 4.7 6.9 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF87 PF01935.17 KZN92071.1 - 0.25 11.4 6.8 0.23 11.5 0.1 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_30 PF13604.6 KZN92071.1 - 0.31 10.7 1.1 4.8 6.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain Pes-10 PF07149.11 KZN92071.1 - 0.93 8.5 8.7 5.5 6.0 0.1 2.1 2 0 0 2 2 2 0 Pes-10 AAA_28 PF13521.6 KZN92071.1 - 3.4 7.9 6.2 1.5 9.0 0.2 3.0 3 0 0 3 3 3 0 AAA domain FMN_red PF03358.15 KZN92072.1 - 5.1e-29 101.0 0.0 6.8e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KZN92072.1 - 3.7e-08 33.3 0.0 5.1e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold DUF3328 PF11807.8 KZN92073.1 - 0.00079 19.3 2.6 0.012 15.4 1.4 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3328) YjbT PF17089.5 KZN92073.1 - 0.18 11.9 0.1 0.89 9.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family Sugar_tr PF00083.24 KZN92078.1 - 6.1e-33 114.3 23.6 1.4e-23 83.5 7.7 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KZN92078.1 - 8.7e-26 90.7 26.9 8.7e-26 90.7 26.9 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TMEM18 PF14770.6 KZN92078.1 - 0.28 11.2 2.1 0.96 9.5 2.1 1.9 1 0 0 1 1 1 0 Transmembrane protein 18 DUF4231 PF14015.6 KZN92078.1 - 6.8 7.2 12.3 7.8 7.0 0.1 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF4231) Transferase PF02458.15 KZN92079.1 - 1.1e-37 129.7 0.0 3.7e-25 88.5 0.0 3.0 2 1 0 2 2 2 2 Transferase family Glyco_hydro_47 PF01532.20 KZN92080.1 - 3e-27 95.6 0.0 2e-17 63.2 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 Pyr_redox_3 PF13738.6 KZN92081.1 - 4e-19 69.0 0.0 3.6e-17 62.6 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KZN92081.1 - 4.7e-17 62.1 0.0 1.9e-14 53.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KZN92081.1 - 1.8e-15 56.4 0.1 6.8e-13 47.9 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KZN92081.1 - 3.4e-10 39.6 0.0 8.6e-08 31.7 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KZN92081.1 - 7.2e-06 26.5 0.2 0.31 11.6 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN92081.1 - 1e-05 25.7 0.0 4e-05 23.8 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KZN92081.1 - 2.8e-05 23.5 0.0 0.0017 17.7 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 KZN92081.1 - 0.00092 18.4 0.0 0.0055 15.8 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KZN92081.1 - 0.0048 15.7 0.6 0.021 13.5 0.0 2.1 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.17 KZN92081.1 - 0.005 16.1 0.0 0.1 11.9 0.0 2.4 2 0 0 2 2 2 1 Thi4 family 2-Hacid_dh_C PF02826.19 KZN92081.1 - 0.0082 15.5 0.0 0.056 12.8 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KZN92081.1 - 0.019 15.0 0.0 4.6 7.3 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KZN92081.1 - 0.025 14.6 0.3 2.2 8.2 0.1 2.8 2 1 0 2 2 2 0 FAD-NAD(P)-binding SnoaL_2 PF12680.7 KZN92081.1 - 0.047 14.3 0.1 0.76 10.4 0.0 2.7 3 0 0 3 3 2 0 SnoaL-like domain DAO PF01266.24 KZN92081.1 - 0.068 12.7 0.0 3.9 6.9 0.0 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KZN92081.1 - 0.071 12.4 0.0 0.68 9.2 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KZN92081.1 - 0.08 13.4 0.0 16 6.0 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.22 KZN92081.1 - 0.12 11.5 0.1 1.1 8.2 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KZN92081.1 - 0.15 12.0 0.1 4 7.3 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KZN92081.1 - 0.18 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SLAC1 PF03595.17 KZN92083.1 - 1e-55 189.3 36.4 1.2e-55 189.1 36.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel HemY_N PF07219.13 KZN92083.1 - 2.9 8.1 8.3 20 5.5 0.7 3.7 3 0 0 3 3 3 0 HemY protein N-terminus Rrn6 PF10214.9 KZN92085.1 - 0.046 12.2 2.1 0.057 11.9 2.1 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CDC45 PF02724.14 KZN92085.1 - 0.25 9.6 0.3 0.31 9.3 0.3 1.1 1 0 0 1 1 1 0 CDC45-like protein F-box PF00646.33 KZN92086.1 - 0.0095 15.8 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KZN92086.1 - 0.029 14.6 0.0 5.1 7.5 0.0 3.5 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 KZN92086.1 - 0.037 13.9 0.1 0.081 12.8 0.1 1.6 1 0 0 1 1 1 0 F-box-like TFIIIC_delta PF12657.7 KZN92086.1 - 0.11 12.4 0.0 1.2 9.0 0.0 2.6 3 0 0 3 3 3 0 Transcription factor IIIC subunit delta N-term Fungal_trans PF04082.18 KZN92087.1 - 4.5e-14 52.1 0.0 1.1e-13 50.8 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN92087.1 - 1.4e-06 28.3 7.0 3.4e-06 27.1 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NIF PF03031.18 KZN92088.1 - 3.1e-42 144.0 0.1 4.2e-42 143.6 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase F-box-like PF12937.7 KZN92089.1 - 0.074 13.0 0.0 0.42 10.6 0.0 2.3 2 1 0 2 2 2 0 F-box-like JAB PF01398.21 KZN92090.1 - 3.7e-33 114.0 0.0 7.8e-33 112.9 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KZN92090.1 - 1.5e-11 44.7 1.0 2.6e-11 43.9 1.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KZN92090.1 - 4.6e-08 32.8 0.0 1.8e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain Hist_deacetyl PF00850.19 KZN92091.1 - 1.6e-83 280.7 0.0 3.5e-83 279.6 0.0 1.5 2 0 0 2 2 2 1 Histone deacetylase domain Ribosomal_L14 PF00238.19 KZN92092.1 - 3.8e-34 117.4 0.0 4.5e-34 117.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Endonuc-FokI_C PF09254.11 KZN92092.1 - 0.078 12.2 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal Vps8 PF12816.7 KZN92093.1 - 0.034 13.6 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 Golgi CORVET complex core vacuolar protein 8 PH PF00169.29 KZN92094.1 - 4.4e-12 46.4 0.0 2.4e-11 44.0 0.0 2.2 1 1 0 1 1 1 1 PH domain SAM_2 PF07647.17 KZN92094.1 - 2.4e-09 37.2 0.1 4.1e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 KZN92094.1 - 2.8e-07 30.3 0.0 5.7e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KZN92094.1 - 2.4e-06 27.0 0.0 5e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SAM_1 PF00536.30 KZN92094.1 - 0.0018 18.7 0.1 0.004 17.6 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.6 KZN92094.1 - 0.0087 16.5 0.0 0.035 14.5 0.0 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KZN92094.1 - 0.091 13.1 0.0 0.29 11.4 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain zf-MIZ PF02891.20 KZN92095.1 - 2.9e-10 39.7 0.3 6.1e-10 38.7 0.3 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KZN92095.1 - 0.00021 21.1 0.4 0.00052 19.8 0.4 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF5102 PF17104.5 KZN92096.1 - 1.2e-110 370.1 1.7 2.3e-110 369.2 1.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) Nsp1_C PF05064.13 KZN92097.1 - 2.2e-40 137.1 0.5 2.2e-40 137.1 0.5 1.9 2 1 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 KZN92097.1 - 1.5e-06 29.0 111.7 0.0027 18.5 36.6 5.9 1 1 4 5 5 4 4 Nucleoporin FG repeat region ParB PF08775.10 KZN92097.1 - 0.028 14.9 0.6 0.062 13.8 0.6 1.5 1 0 0 1 1 1 0 ParB family Laminin_II PF06009.12 KZN92097.1 - 0.039 14.0 8.0 12 5.9 2.1 3.2 1 1 2 3 3 3 0 Laminin Domain II DUF1664 PF07889.12 KZN92097.1 - 0.21 11.6 5.2 0.99 9.5 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) POTRA_TamA_1 PF17243.2 KZN92097.1 - 0.28 11.3 1.1 0.94 9.6 0.1 2.2 2 0 0 2 2 2 0 POTRA domain TamA domain 1 AAA_13 PF13166.6 KZN92097.1 - 0.37 9.4 1.9 0.56 8.8 1.9 1.3 1 0 0 1 1 1 0 AAA domain DUF16 PF01519.16 KZN92097.1 - 0.48 10.9 5.1 0.31 11.6 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF4407 PF14362.6 KZN92097.1 - 0.51 9.6 4.9 0.85 8.9 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 KZN92097.1 - 0.55 10.6 6.6 0.39 11.1 0.3 2.3 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) DUF4200 PF13863.6 KZN92097.1 - 0.66 10.4 5.3 2 8.8 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF948 PF06103.11 KZN92097.1 - 0.84 9.9 5.7 1.3 9.3 1.7 2.9 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) LTXXQ PF07813.12 KZN92097.1 - 0.92 10.3 2.9 0.64 10.8 0.1 2.2 2 1 0 2 2 1 0 LTXXQ motif family protein CK2S PF15011.6 KZN92097.1 - 1.3 8.9 3.8 21 4.9 0.5 2.4 2 0 0 2 2 2 0 Casein Kinase 2 substrate Snapin_Pallidin PF14712.6 KZN92097.1 - 1.7 9.2 4.4 5.2 7.6 0.1 2.4 2 0 0 2 2 2 0 Snapin/Pallidin HIP1_clath_bdg PF16515.5 KZN92097.1 - 1.8 9.2 9.0 10 6.8 5.0 2.7 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 IFT57 PF10498.9 KZN92097.1 - 1.9 7.4 7.7 0.9 8.4 0.9 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 V-SNARE PF05008.15 KZN92097.1 - 2.2 8.7 6.1 7.6 7.0 0.2 3.0 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus EzrA PF06160.12 KZN92097.1 - 2.3 6.3 5.1 0.86 7.7 0.9 1.8 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA MscS_porin PF12795.7 KZN92097.1 - 5.6 6.4 9.3 11 5.5 3.4 2.3 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain APG6_N PF17675.1 KZN92097.1 - 6.6 7.3 7.0 12 6.4 6.1 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region IATP PF04568.12 KZN92098.1 - 5e-35 119.9 0.4 5.4e-35 119.7 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP GFD1 PF17331.2 KZN92098.1 - 0.0071 16.5 3.2 0.011 15.8 3.2 1.4 1 0 0 1 1 1 1 GFD1 mRNA transport factor BLOC1_2 PF10046.9 KZN92098.1 - 0.033 14.5 0.7 0.038 14.3 0.7 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4140 PF13600.6 KZN92098.1 - 0.05 14.0 1.0 0.13 12.7 0.4 1.8 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF2730 PF10805.8 KZN92098.1 - 0.077 13.1 0.6 0.11 12.6 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) 14-3-3 PF00244.20 KZN92099.1 - 8e-105 349.2 5.3 9.3e-105 349.0 5.3 1.0 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.17 KZN92099.1 - 0.099 11.0 3.4 0.15 10.5 3.4 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 DUF2205 PF10224.9 KZN92100.1 - 1.1e-33 115.0 2.0 1.1e-33 115.0 2.0 1.7 2 0 0 2 2 2 1 Short coiled-coil protein TPR_MLP1_2 PF07926.12 KZN92100.1 - 0.0066 16.5 2.5 0.011 15.8 2.5 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein HALZ PF02183.18 KZN92100.1 - 0.015 15.5 5.0 0.036 14.3 0.4 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper DUF2884 PF11101.8 KZN92100.1 - 0.018 14.6 1.3 0.025 14.1 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) YabA PF06156.13 KZN92100.1 - 0.029 15.0 2.2 0.043 14.5 2.2 1.3 1 0 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 KZN92100.1 - 0.033 14.0 2.0 0.053 13.3 2.0 1.4 1 0 0 1 1 1 0 Septum formation initiator Tup_N PF08581.10 KZN92100.1 - 0.11 12.8 2.7 7.7 6.9 0.1 2.2 1 1 1 2 2 2 0 Tup N-terminal Baculo_PEP_C PF04513.12 KZN92100.1 - 0.11 12.5 0.5 0.15 12.1 0.5 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus bZIP_1 PF00170.21 KZN92100.1 - 0.14 12.3 5.1 0.45 10.6 5.1 1.8 1 1 1 2 2 2 0 bZIP transcription factor DUF5320 PF17253.2 KZN92100.1 - 0.24 12.5 2.9 0.38 11.9 1.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5320) Glyco_hydro_76 PF03663.14 KZN92101.1 - 2.2e-18 67.0 1.2 5.1e-12 46.0 0.1 3.0 3 1 0 3 3 3 2 Glycosyl hydrolase family 76 RRM_1 PF00076.22 KZN92102.1 - 5.9e-12 45.2 0.0 7.2e-05 22.5 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KZN92102.1 - 0.027 14.0 0.0 0.77 9.4 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NLBH PF05211.12 KZN92102.1 - 0.073 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) RRM_occluded PF16842.5 KZN92102.1 - 0.17 11.8 0.0 19 5.2 0.0 2.1 2 0 0 2 2 2 0 Occluded RNA-recognition motif Bax1-I PF01027.20 KZN92103.1 - 1e-33 116.9 10.5 1.6e-33 116.3 10.5 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF3995 PF13160.6 KZN92103.1 - 1.2 9.5 11.5 0.11 12.9 2.5 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3995) CGI-121 PF08617.10 KZN92104.1 - 4.8e-55 186.1 0.5 5.5e-55 185.9 0.5 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Slx4 PF09494.10 KZN92105.1 - 5.8e-27 93.4 0.0 1.2e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 Slx4 endonuclease Zn_clus PF00172.18 KZN92106.1 - 0.00014 21.9 8.9 0.00024 21.2 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TSC22 PF01166.18 KZN92106.1 - 0.0026 18.0 0.3 0.0068 16.7 0.2 1.6 2 0 0 2 2 2 1 TSC-22/dip/bun family ZapB PF06005.12 KZN92106.1 - 0.0026 18.1 1.2 0.0041 17.5 0.7 1.5 2 0 0 2 2 2 1 Cell division protein ZapB ADIP PF11559.8 KZN92106.1 - 0.01 15.9 0.3 0.017 15.2 0.3 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding WXG100 PF06013.12 KZN92106.1 - 0.024 14.8 0.1 0.037 14.3 0.1 1.3 1 0 0 1 1 1 0 Proteins of 100 residues with WXG AKNA PF12443.8 KZN92106.1 - 0.03 15.0 0.7 0.059 14.0 0.7 1.5 1 0 0 1 1 1 0 AT-hook-containing transcription factor bZIP_2 PF07716.15 KZN92106.1 - 0.031 14.3 3.2 0.086 12.9 3.2 1.7 1 0 0 1 1 1 0 Basic region leucine zipper DivIC PF04977.15 KZN92106.1 - 0.061 13.1 1.4 0.1 12.4 1.4 1.3 1 0 0 1 1 1 0 Septum formation initiator Prefoldin PF02996.17 KZN92106.1 - 0.061 13.2 0.9 0.11 12.4 0.9 1.3 1 0 0 1 1 1 0 Prefoldin subunit Sec3_C_2 PF15278.6 KZN92106.1 - 0.084 13.2 0.1 0.12 12.7 0.1 1.2 1 0 0 1 1 1 0 Sec3 exocyst complex subunit Nnf1 PF03980.14 KZN92106.1 - 0.093 13.1 0.7 0.093 13.1 0.7 1.8 2 0 0 2 2 2 0 Nnf1 FliD_C PF07195.12 KZN92106.1 - 0.13 11.7 0.3 0.16 11.3 0.3 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus RRP14 PF15459.6 KZN92106.1 - 0.2 12.3 2.6 0.28 11.8 0.2 2.2 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 DUF4618 PF15397.6 KZN92106.1 - 1.3 8.3 8.4 0.12 11.8 1.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) ER_lumen_recept PF00810.18 KZN92108.1 - 3.5e-44 151.2 7.9 5.6e-44 150.5 7.9 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KZN92108.1 - 0.052 13.3 0.1 0.052 13.3 0.1 3.8 5 1 0 5 5 5 0 PQ loop repeat DUF5314 PF17241.2 KZN92108.1 - 0.12 12.0 0.4 0.29 10.8 0.4 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5314) Tlr3_TMD PF17968.1 KZN92108.1 - 0.57 10.4 4.2 1.8 8.8 4.2 1.8 1 0 0 1 1 1 0 Toll-like receptor 3 trans-membrane domain Myb_DNA-binding PF00249.31 KZN92109.1 - 1.3e-15 57.2 4.6 4.4e-09 36.4 0.7 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KZN92109.1 - 6.9e-10 39.0 1.4 8e-06 26.0 0.1 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KZN92109.1 - 0.036 14.0 1.0 0.063 13.2 0.8 1.4 1 1 0 1 1 1 0 Myb DNA-binding like RHIM PF12721.7 KZN92109.1 - 0.097 13.2 4.2 0.28 11.7 4.2 1.8 1 0 0 1 1 1 0 RIP homotypic interaction motif Transp_cyt_pur PF02133.15 KZN92110.1 - 1e-17 64.1 36.6 1.5e-17 63.6 36.6 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin COX5B PF01215.19 KZN92111.1 - 8.7e-56 187.1 0.0 1.1e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-UBP PF02148.19 KZN92111.1 - 0.068 13.5 0.3 0.1 12.9 0.3 1.3 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Myb_DNA-bind_6 PF13921.6 KZN92112.1 - 1.1e-06 28.8 1.2 0.0012 19.1 0.3 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KZN92112.1 - 6e-05 23.1 0.9 0.00089 19.4 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain RseA_C PF03873.13 KZN92112.1 - 0.16 12.2 5.5 0.26 11.5 0.2 2.9 2 1 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain PROCN PF08083.11 KZN92113.1 - 8.6e-234 775.6 8.0 8.6e-234 775.6 8.0 1.9 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KZN92113.1 - 1.9e-126 420.3 1.4 3.6e-126 419.4 1.4 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KZN92113.1 - 2.8e-85 284.1 1.5 1.2e-57 194.3 0.2 3.2 3 0 0 3 3 3 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KZN92113.1 - 6.7e-81 269.6 2.4 1.9e-80 268.1 2.4 1.9 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KZN92113.1 - 4.5e-71 237.2 0.1 1e-70 236.0 0.1 1.7 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 KZN92113.1 - 1.2e-47 160.8 0.0 3.3e-47 159.4 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 KZN92113.1 - 5.7e-47 158.0 0.2 1.6e-46 156.5 0.2 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Hom_end_hint PF05203.16 KZN92113.1 - 6.6e-10 39.3 1.3 1.7e-09 38.0 0.0 2.2 2 0 0 2 2 2 1 Hom_end-associated Hint OCD_Mu_crystall PF02423.15 KZN92113.1 - 0.3 10.0 1.0 4.5 6.1 0.6 2.2 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family Ribosomal_L34e PF01199.18 KZN92114.1 - 7.3e-40 135.2 0.4 1.1e-39 134.7 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Vps36-NZF-N PF16988.5 KZN92114.1 - 0.027 13.9 0.0 0.057 12.8 0.0 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Forkhead PF00250.18 KZN92115.1 - 7.9e-22 77.3 0.0 1.5e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Cactin_mid PF10312.9 KZN92116.1 - 1.1e-62 211.3 5.2 1.9e-62 210.5 5.2 1.4 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 KZN92116.1 - 7e-58 194.0 4.2 1.2e-57 193.2 4.2 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein DUF1087 PF06465.13 KZN92116.1 - 0.022 14.8 0.3 0.079 13.0 0.3 2.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) XLF PF09302.11 KZN92117.1 - 1.3e-51 175.3 1.4 2.1e-51 174.6 1.4 1.3 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component WD40 PF00400.32 KZN92118.1 - 7.2e-16 58.3 22.2 3.1e-05 24.6 0.2 7.5 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN92118.1 - 2.2e-07 31.1 0.0 1.4 9.3 0.0 5.2 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KZN92118.1 - 3.1e-05 23.9 0.0 0.11 12.4 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A zf-C2H2_aberr PF17017.5 KZN92118.1 - 0.0043 17.2 0.2 0.051 13.7 0.0 2.1 2 0 0 2 2 2 1 Aberrant zinc-finger CLAMP PF14769.6 KZN92118.1 - 0.058 13.8 0.4 0.13 12.8 0.4 1.5 1 0 0 1 1 1 0 Flagellar C1a complex subunit C1a-32 Zn_ribbon_17 PF17120.5 KZN92118.1 - 1.6 8.4 10.9 4.6 6.9 10.9 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type ABC_membrane PF00664.23 KZN92119.1 - 1.8e-34 119.7 12.2 6.3e-34 117.9 9.0 2.6 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 KZN92119.1 - 3.8e-33 114.9 0.0 1.8e-32 112.7 0.0 2.1 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 KZN92119.1 - 5.5e-08 32.5 0.1 2e-06 27.4 0.0 2.6 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KZN92119.1 - 0.0041 17.5 0.0 0.013 15.9 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain SbcCD_C PF13558.6 KZN92119.1 - 0.02 15.1 0.4 0.5 10.7 0.4 2.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 KZN92119.1 - 0.02 15.1 0.1 0.22 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KZN92119.1 - 0.038 13.7 0.2 0.093 12.5 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KZN92119.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase DUF498 PF04430.14 KZN92120.1 - 2.8e-28 98.2 0.0 4e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Alk_phosphatase PF00245.20 KZN92121.1 - 7.4e-105 351.3 0.0 9e-105 351.0 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 KZN92121.1 - 0.00027 20.4 0.0 0.00064 19.2 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily SelK_SelG PF10961.8 KZN92121.1 - 0.13 12.8 0.0 0.29 11.8 0.0 1.5 1 0 0 1 1 1 0 Selenoprotein SelK_SelG SET PF00856.28 KZN92123.1 - 4e-14 53.4 0.1 3.1e-13 50.5 0.1 2.3 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.17 KZN92123.1 - 3e-08 33.1 5.1 0.076 13.2 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KZN92123.1 - 2.9e-06 26.8 3.2 0.00046 19.9 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KZN92123.1 - 0.00011 22.7 0.2 1.8 9.6 0.0 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KZN92123.1 - 0.012 15.0 1.1 0.64 9.3 1.3 2.4 2 0 0 2 2 2 0 MalT-like TPR region TPR_11 PF13414.6 KZN92123.1 - 0.018 14.7 0.1 0.076 12.7 0.1 2.1 2 0 0 2 2 2 0 TPR repeat YfiO PF13525.6 KZN92123.1 - 0.018 14.7 0.0 0.043 13.5 0.0 1.5 1 1 0 1 1 1 0 Outer membrane lipoprotein TPR_9 PF13371.6 KZN92123.1 - 0.057 13.6 0.3 0.5 10.5 0.3 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KZN92123.1 - 0.095 13.0 0.1 6.3 7.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KZN92123.1 - 0.4 11.4 3.6 4 8.2 0.0 3.3 3 1 0 4 4 4 0 Tetratricopeptide repeat Clr5 PF14420.6 KZN92124.1 - 5.3e-09 36.2 0.0 9.2e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Clr5 domain NPP PF08384.10 KZN92124.1 - 0.14 12.2 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 Pro-opiomelanocortin, N-terminal region Methyltransf_23 PF13489.6 KZN92127.1 - 5.9e-16 58.7 0.0 1.1e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN92127.1 - 5.6e-09 36.6 0.0 1.8e-08 35.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN92127.1 - 0.00047 20.8 0.0 0.007 17.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN92127.1 - 0.00061 20.4 0.0 0.0022 18.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN92127.1 - 0.0016 18.2 0.0 0.0043 16.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KZN92127.1 - 0.0036 16.8 0.0 0.0097 15.4 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KZN92127.1 - 0.0097 15.5 0.0 0.04 13.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KZN92127.1 - 0.023 14.0 0.0 1 8.6 0.0 2.1 2 0 0 2 2 2 0 O-methyltransferase domain Ubie_methyltran PF01209.18 KZN92127.1 - 0.095 12.0 0.0 4 6.7 0.0 2.4 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Glyco_hydro_16 PF00722.21 KZN92128.1 - 2.8e-46 157.2 9.1 5.2e-46 156.3 9.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1828 PF08861.10 KZN92128.1 - 0.066 13.5 0.1 0.21 11.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF1828 MAGP PF05507.11 KZN92128.1 - 0.088 13.2 0.6 0.36 11.2 0.6 2.0 2 0 0 2 2 2 0 Microfibril-associated glycoprotein (MAGP) Chitin_bind_1 PF00187.19 KZN92128.1 - 1.2 9.7 15.1 2.6 8.6 15.1 1.6 1 0 0 1 1 1 0 Chitin recognition protein cNMPbd_u2 PF16643.5 KZN92131.1 - 6.3e-38 130.7 9.1 1.5e-37 129.5 9.1 1.6 1 0 0 1 1 1 1 Unstructured region on cNMP-binding protein cNMP_binding PF00027.29 KZN92131.1 - 6.8e-36 122.2 0.0 6.7e-22 77.4 0.0 3.0 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.6 KZN92131.1 - 2.2e-10 39.7 4.0 1.8 8.8 0.0 8.4 9 0 0 9 9 9 2 Leucine Rich repeat LRR_4 PF12799.7 KZN92131.1 - 5e-09 36.3 0.5 0.13 12.8 0.2 6.7 6 1 2 8 8 8 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KZN92131.1 - 1.5e-06 28.0 0.2 4e-06 26.6 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN92131.1 - 1.6e-05 24.6 0.9 7.6e-05 22.5 0.9 2.2 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.33 KZN92131.1 - 0.0077 16.6 8.8 45 5.1 0.0 7.7 7 1 1 8 8 8 0 Leucine Rich Repeat SAM_Ste50p PF09235.10 KZN92131.1 - 0.6 10.4 4.1 5.4 7.3 0.5 3.4 4 0 0 4 4 4 0 Ste50p, sterile alpha motif Tim17 PF02466.19 KZN92132.1 - 0.036 14.4 1.1 0.065 13.6 1.1 1.5 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Kinesin PF00225.23 KZN92134.1 - 4.1e-116 387.5 0.0 6.4e-116 386.9 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KZN92134.1 - 1.8e-26 92.9 0.0 4e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding AAA_33 PF13671.6 KZN92134.1 - 0.0058 16.8 0.6 0.22 11.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain PMSR PF01625.21 KZN92135.1 - 9e-61 204.5 0.3 1e-60 204.3 0.3 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Vsr PF03852.15 KZN92135.1 - 0.13 12.1 0.1 5.1 7.0 0.0 2.3 2 0 0 2 2 2 0 DNA mismatch endonuclease Vsr Abhydrolase_6 PF12697.7 KZN92136.1 - 1.7e-11 45.2 0.2 3.3e-11 44.2 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KZN92136.1 - 3.5e-09 36.3 0.0 1.1e-08 34.6 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KZN92136.1 - 1.1e-08 35.1 1.4 8.6e-08 32.1 1.4 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 KZN92136.1 - 0.0025 17.4 0.2 1 8.9 0.0 3.0 2 1 1 3 3 3 2 Dienelactone hydrolase family DUF2048 PF09752.9 KZN92136.1 - 0.015 14.4 0.6 0.03 13.4 0.3 1.6 2 0 0 2 2 2 0 Abhydrolase domain containing 18 Lipase_3 PF01764.25 KZN92136.1 - 0.097 12.5 0.4 0.27 11.1 0.2 1.7 2 0 0 2 2 2 0 Lipase (class 3) TRP PF06011.12 KZN92138.1 - 8.1e-133 443.2 25.0 9.6e-133 443.0 25.0 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KZN92138.1 - 3.9e-34 118.0 0.2 6.5e-34 117.3 0.2 1.4 1 0 0 1 1 1 1 ML-like domain DUF5472 PF17566.2 KZN92138.1 - 0.29 11.1 5.6 0.24 11.4 1.2 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5472) Sugar_tr PF00083.24 KZN92139.1 - 5.3e-131 437.6 25.2 6.1e-131 437.4 25.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN92139.1 - 1.8e-22 79.7 44.0 9.2e-18 64.3 18.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.7 KZN92140.1 - 6.4e-50 167.7 2.5 6.2e-14 52.4 0.0 5.4 4 1 3 7 7 7 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN92140.1 - 2.2e-31 107.8 2.3 4.3e-08 33.6 0.0 7.3 4 2 3 7 7 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KZN92140.1 - 8.3e-28 95.6 10.1 0.0018 18.6 0.1 8.7 8 1 0 8 8 7 7 Ankyrin repeat Ank_5 PF13857.6 KZN92140.1 - 3.6e-24 84.5 2.7 0.00025 21.3 0.0 8.3 2 1 6 8 8 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN92140.1 - 5.7e-18 63.1 7.1 0.21 12.3 0.0 9.1 11 0 0 11 11 7 5 Ankyrin repeat Helo_like_N PF17111.5 KZN92140.1 - 7.2e-10 38.6 0.2 1.4e-09 37.6 0.2 1.6 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins NACHT PF05729.12 KZN92140.1 - 0.011 15.7 0.2 0.024 14.6 0.2 1.6 1 0 0 1 1 1 0 NACHT domain Jnk-SapK_ap_N PF09744.9 KZN92140.1 - 0.035 14.3 0.3 0.091 13.0 0.3 1.6 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 F_actin_bind PF08919.10 KZN92140.1 - 0.066 13.3 0.3 0.29 11.3 0.3 2.2 1 0 0 1 1 1 0 F-actin binding SesA PF17107.5 KZN92140.1 - 0.069 13.3 0.6 0.25 11.5 0.7 2.0 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases CAP_N PF01213.19 KZN92140.1 - 0.11 11.9 1.3 0.22 11.0 1.3 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal AAA_13 PF13166.6 KZN92140.1 - 0.15 10.6 3.5 0.33 9.5 3.5 1.4 1 1 0 1 1 1 0 AAA domain SKA2 PF16740.5 KZN92140.1 - 0.16 11.8 3.6 0.45 10.3 3.6 1.7 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 SpoIISA_toxin PF14171.6 KZN92140.1 - 0.34 10.6 1.8 0.86 9.2 1.8 1.6 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Occludin_ELL PF07303.13 KZN92140.1 - 0.47 11.2 3.5 2.6 8.8 0.8 2.8 2 1 0 2 2 2 0 Occludin homology domain APG5 PF04106.12 KZN92141.1 - 1.5e-62 211.2 0.0 1.9e-62 210.9 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 SAM_2 PF07647.17 KZN92142.1 - 3e-10 40.1 0.0 5.6e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KZN92142.1 - 6e-09 36.2 0.2 1.8e-08 34.7 0.1 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH PF00169.29 KZN92142.1 - 1.3e-05 25.7 0.0 2.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KZN92142.1 - 0.19 12.2 0.5 0.43 11.0 0.5 1.6 1 1 0 1 1 1 0 Pleckstrin homology domain Fungal_trans_2 PF11951.8 KZN92143.1 - 1.9e-89 300.2 0.0 2.8e-89 299.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN92143.1 - 5.1e-08 32.9 8.3 9e-08 32.1 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPX PF03105.19 KZN92144.1 - 2.5 7.9 8.0 3.1 7.6 8.0 1.1 1 0 0 1 1 1 0 SPX domain SHR3_chaperone PF08229.11 KZN92146.1 - 1.5e-79 265.4 0.0 1.7e-79 265.2 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF5453 PF17534.2 KZN92146.1 - 0.029 14.3 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5453) Arrestin_N PF00339.29 KZN92147.1 - 8.9e-15 55.0 0.0 5.4e-14 52.5 0.0 2.2 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KZN92147.1 - 1.1e-07 32.4 0.0 7.8e-05 23.1 0.0 2.8 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain WD40 PF00400.32 KZN92148.1 - 3.9e-16 59.1 18.7 4.9e-05 24.0 0.5 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN92148.1 - 3.7e-08 33.6 0.0 0.066 13.5 0.0 4.1 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain COQ7 PF03232.13 KZN92150.1 - 0.055 13.3 0.1 0.079 12.7 0.1 1.2 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 HRXXH PF13933.6 KZN92151.1 - 1.6e-110 368.5 0.0 1.9e-110 368.2 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 KZN92151.1 - 0.00019 22.0 0.0 0.00035 21.1 0.0 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Zip PF02535.22 KZN92152.1 - 2.9e-37 128.6 20.2 2.9e-37 128.6 20.2 2.0 2 0 0 2 2 2 1 ZIP Zinc transporter Thyroglobulin_1 PF00086.18 KZN92152.1 - 0.055 13.1 0.3 9.6 6.0 0.0 2.6 2 0 0 2 2 2 0 Thyroglobulin type-1 repeat Acetyltransf_10 PF13673.7 KZN92153.1 - 4e-09 36.5 0.0 5.9e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KZN92153.1 - 6.2e-08 32.9 0.0 8.4e-08 32.5 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KZN92153.1 - 6.7e-08 32.8 0.0 1.1e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KZN92153.1 - 7.5e-05 22.8 0.0 0.0026 17.8 0.0 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KZN92153.1 - 0.00093 19.3 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KZN92153.1 - 0.0034 17.3 0.0 0.0051 16.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein MFS_1 PF07690.16 KZN92156.1 - 2.4e-29 102.4 39.0 2.4e-29 102.4 39.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN92156.1 - 1.9e-08 33.6 36.3 1.6e-07 30.6 11.0 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter Peptidase_S10 PF00450.22 KZN92157.1 - 2.6e-90 303.8 0.0 3.5e-90 303.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Myotub-related PF06602.14 KZN92157.1 - 0.17 10.7 0.1 0.34 9.8 0.1 1.4 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain MFS_1 PF07690.16 KZN92158.1 - 3.6e-28 98.5 39.6 1.4e-16 60.4 29.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN92158.1 - 4.6e-16 58.7 19.7 2.8e-15 56.1 19.7 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter Pkinase PF00069.25 KZN92159.1 - 2.5e-69 233.6 0.0 4.5e-69 232.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN92159.1 - 2.5e-32 112.2 0.0 1e-30 106.9 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KZN92159.1 - 0.005 16.8 0.1 0.89 9.4 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KZN92159.1 - 0.033 13.0 0.0 0.07 11.9 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KZN92159.1 - 0.054 12.8 1.4 6.8 5.9 0.0 3.4 4 0 0 4 4 4 0 Kinase-like Abhydrolase_1 PF00561.20 KZN92160.1 - 3.4e-10 40.0 0.0 3.2e-09 36.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KZN92160.1 - 8.8e-10 38.3 0.0 8.6e-09 35.0 0.0 2.1 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KZN92160.1 - 3.1e-09 37.8 0.0 4e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KZN92160.1 - 1.9e-05 24.7 0.0 3.7e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold UPF0227 PF05728.12 KZN92160.1 - 2.3e-05 24.4 0.0 0.023 14.6 0.1 2.2 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0227) FSH1 PF03959.13 KZN92160.1 - 0.00072 19.3 0.0 0.0046 16.6 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 KZN92160.1 - 0.0017 17.9 0.0 0.44 10.0 0.0 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family Palm_thioest PF02089.15 KZN92160.1 - 0.028 14.2 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Thioesterase PF00975.20 KZN92160.1 - 0.18 11.9 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain p450 PF00067.22 KZN92163.1 - 7.5e-37 127.1 0.0 8.4e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KZN92164.1 - 3.2e-09 36.2 0.6 5.3e-09 35.5 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN92164.1 - 6.3e-06 26.2 9.8 1.2e-05 25.3 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GRDP-like PF07173.12 KZN92165.1 - 4.5e-16 59.8 7.0 3.9e-13 50.2 0.1 2.9 3 0 0 3 3 3 2 Glycine-rich domain-containing protein-like zf-C2H2 PF00096.26 KZN92166.1 - 0.41 11.2 2.5 1 10.0 2.5 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type Methyltransf_31 PF13847.6 KZN92169.1 - 2.4e-12 46.9 0.0 3e-07 30.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KZN92169.1 - 9e-11 41.9 0.0 1.3e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN92169.1 - 1.6e-07 31.9 0.0 0.00012 22.6 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 KZN92169.1 - 1.6e-07 31.9 0.0 5.1e-06 27.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN92169.1 - 1.9e-06 28.5 2.1 1.1e-05 26.1 0.1 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 KZN92169.1 - 0.00023 21.2 0.0 0.00039 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KZN92169.1 - 0.0033 17.0 0.0 0.0071 16.0 0.0 1.5 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW MTS PF05175.14 KZN92169.1 - 0.006 16.1 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KZN92169.1 - 0.0061 16.7 0.0 0.0091 16.1 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase ACAS_N PF16177.5 KZN92169.1 - 0.034 14.0 0.3 0.22 11.5 0.0 2.2 2 0 0 2 2 2 0 Acetyl-coenzyme A synthetase N-terminus PCMT PF01135.19 KZN92169.1 - 0.045 13.5 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pox_MCEL PF03291.16 KZN92169.1 - 0.12 11.5 0.0 0.28 10.3 0.0 1.5 2 0 0 2 2 2 0 mRNA capping enzyme BUD22 PF09073.10 KZN92169.1 - 0.14 11.5 7.9 0.18 11.1 7.9 1.1 1 0 0 1 1 1 0 BUD22 FAM176 PF14851.6 KZN92169.1 - 0.29 10.8 7.8 0.64 9.7 3.6 2.2 2 0 0 2 2 2 0 FAM176 family RXT2_N PF08595.11 KZN92169.1 - 3.6 7.6 9.7 0.85 9.6 2.6 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 KZN92169.1 - 5.2 7.5 15.8 13 6.2 11.4 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DSPc PF00782.20 KZN92170.1 - 1e-23 83.6 0.0 4.4e-21 75.1 0.0 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KZN92170.1 - 0.047 13.2 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase KH_1 PF00013.29 KZN92172.1 - 6.5e-41 138.0 8.7 1.9e-16 59.7 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KZN92172.1 - 3.8e-09 36.3 11.0 0.0036 17.1 0.7 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KZN92172.1 - 2.7e-07 30.4 5.9 0.055 13.4 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KZN92172.1 - 0.0003 20.8 5.7 0.41 10.8 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain GARS_C PF02843.16 KZN92172.1 - 0.013 15.8 0.4 0.89 9.9 0.0 2.7 3 0 0 3 3 3 0 Phosphoribosylglycinamide synthetase, C domain ECR1_N PF14382.6 KZN92172.1 - 0.093 12.6 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region ADH_N PF08240.12 KZN92173.1 - 1.8e-29 101.8 1.2 3e-29 101.1 1.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN92173.1 - 1e-17 64.3 0.0 2e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KZN92173.1 - 0.00025 20.9 0.3 0.00065 19.6 0.3 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 KZN92173.1 - 0.00073 19.1 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KZN92173.1 - 0.038 15.0 0.0 0.074 14.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Yippee-Mis18 PF03226.14 KZN92174.1 - 4.2e-19 68.7 1.5 4.9e-19 68.5 1.5 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 KZN92174.1 - 0.0098 16.1 0.7 0.013 15.7 0.7 1.3 1 0 0 1 1 1 1 C-terminal domain of RIG-I DUF2039 PF10217.9 KZN92174.1 - 0.035 14.4 2.3 0.037 14.4 0.5 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) WD40 PF00400.32 KZN92175.1 - 6.9e-12 45.7 5.0 3.2 8.8 0.0 8.5 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN92175.1 - 3e-08 33.9 0.1 0.14 12.5 0.0 6.8 4 2 4 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KZN92175.1 - 0.00054 19.6 0.4 0.66 9.5 0.0 3.4 2 1 2 4 4 4 4 PQQ-like domain PD40 PF07676.12 KZN92175.1 - 0.03 14.3 0.0 16 5.6 0.0 3.1 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KZN92175.1 - 0.034 13.1 0.0 0.19 10.7 0.0 2.2 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cyclin_N PF00134.23 KZN92176.1 - 6.7e-36 122.8 0.2 6.7e-36 122.8 0.2 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KZN92176.1 - 2.6e-13 50.1 1.6 6.6e-13 48.8 1.6 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain UvrD-helicase PF00580.21 KZN92178.1 - 2.9e-62 211.0 0.9 5.4e-60 203.5 0.1 3.0 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KZN92178.1 - 1.3e-57 195.8 0.1 4.9e-57 193.9 0.0 1.8 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KZN92178.1 - 5.5e-31 107.9 0.0 1.7e-30 106.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 KZN92178.1 - 1.3e-14 53.7 0.1 3e-14 52.6 0.1 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KZN92178.1 - 7.6e-09 35.6 0.2 0.00042 20.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.6 KZN92178.1 - 2e-06 27.6 0.0 0.00015 21.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KZN92178.1 - 0.00029 20.6 0.3 0.22 11.3 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KZN92178.1 - 0.0011 19.3 0.7 0.092 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Rrp15p PF07890.12 KZN92178.1 - 0.002 18.4 1.0 0.0053 17.1 0.1 2.1 2 0 0 2 2 2 1 Rrp15p AAA_11 PF13086.6 KZN92178.1 - 0.0041 16.9 0.0 0.0041 16.9 0.0 2.4 3 1 0 3 3 3 1 AAA domain Prenyltransf PF01255.19 KZN92178.1 - 0.12 11.9 0.1 0.31 10.5 0.1 1.7 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase AAA_16 PF13191.6 KZN92178.1 - 0.51 10.7 2.4 1.4 9.3 0.1 2.6 2 1 0 2 2 2 0 AAA ATPase domain p450 PF00067.22 KZN92179.1 - 5.3e-60 203.5 0.0 7e-60 203.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FmdA_AmdA PF03069.15 KZN92180.1 - 6.2e-54 183.3 0.0 1e-31 110.1 0.0 2.1 1 1 1 2 2 2 2 Acetamidase/Formamidase family PP2C PF00481.21 KZN92181.1 - 3.5e-42 144.8 0.1 4.3e-42 144.5 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KZN92181.1 - 2.9e-06 27.1 0.0 1.9e-05 24.4 0.0 2.3 1 1 1 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 KZN92181.1 - 0.00013 21.9 0.1 0.079 12.9 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) CMV_US PF08001.11 KZN92181.1 - 0.12 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 CMV US Cyt-b5 PF00173.28 KZN92182.1 - 5.5e-14 52.1 0.0 8.2e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FKBP_C PF00254.28 KZN92183.1 - 1.2e-32 112.1 0.0 1.4e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Sugar_tr PF00083.24 KZN92184.1 - 8.6e-55 186.4 26.1 1.4e-53 182.4 26.1 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN92184.1 - 4.3e-15 55.5 37.4 8.2e-08 31.6 14.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Zip PF02535.22 KZN92185.1 - 6.1e-67 226.2 8.9 6.9e-67 226.0 8.9 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter PRP9_N PF16958.5 KZN92186.1 - 0.01 15.9 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor PRP9 N-terminus Tom37 PF10568.9 KZN92187.1 - 4e-35 120.9 2.0 2.9e-20 72.8 0.0 2.4 2 0 0 2 2 2 2 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 KZN92187.1 - 1.7e-06 27.8 0.1 6.5e-06 25.8 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KZN92187.1 - 8e-05 23.3 0.0 0.00025 21.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain PEP_mutase PF13714.6 KZN92189.1 - 4.9e-46 157.1 0.7 5.7e-46 156.9 0.7 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KZN92189.1 - 6.8e-19 67.7 0.1 9.6e-19 67.3 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Hist_deacetyl PF00850.19 KZN92190.1 - 8.9e-77 258.6 0.1 1.3e-76 258.1 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Oxysterol_BP PF01237.18 KZN92191.1 - 3.8e-90 302.4 0.0 1.4e-87 293.9 0.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein DUF3605 PF12239.8 KZN92192.1 - 6.6e-56 188.9 0.1 8.6e-56 188.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Isochorismatase PF00857.20 KZN92193.1 - 2.4e-25 89.7 0.0 4.8e-25 88.7 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family DUF1131 PF06572.12 KZN92193.1 - 0.047 13.4 0.1 0.092 12.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1131) Ssu72 PF04722.13 KZN92194.1 - 1.2e-80 269.6 0.0 1.4e-80 269.4 0.0 1.1 1 0 0 1 1 1 1 Ssu72-like protein PRIMA1 PF16101.5 KZN92194.1 - 0.29 11.2 2.1 0.5 10.4 2.1 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Dscam_C PF12355.8 KZN92194.1 - 0.34 11.9 5.1 0.18 12.8 2.5 1.8 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal Mito_fiss_reg PF05308.11 KZN92194.1 - 0.61 10.1 2.7 0.93 9.5 2.7 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 KZN92194.1 - 2.3 7.6 8.6 3.5 7.0 8.6 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SNF2_N PF00176.23 KZN92195.1 - 3.5e-48 164.1 0.0 5.9e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 KZN92195.1 - 5.8e-27 93.6 0.0 1.8e-26 92.0 0.0 1.9 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 KZN92195.1 - 2e-21 76.4 0.0 9.2e-19 67.8 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KZN92195.1 - 7.9e-09 35.7 0.0 2.2e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KZN92195.1 - 2.2e-06 27.1 0.0 4.4e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 KZN92195.1 - 0.018 14.8 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Formin_GBD_N PF18382.1 KZN92195.1 - 0.09 13.2 0.8 0.9 10.0 0.0 3.0 3 0 0 3 3 3 0 Formin N-terminal GTPase-binding domain RNase_PH PF01138.21 KZN92196.1 - 1.4e-31 109.7 0.8 2e-31 109.2 0.2 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Ctr PF04145.15 KZN92197.1 - 5.7e-41 140.6 0.0 1.4e-40 139.3 0.0 1.6 1 1 0 1 1 1 1 Ctr copper transporter family Oxidored_q3 PF00499.20 KZN92197.1 - 0.00073 19.3 1.7 0.0049 16.6 2.6 1.7 2 0 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Fumble PF03630.14 KZN92197.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Fumble LapA_dom PF06305.11 KZN92197.1 - 2.3 8.1 3.8 1.6 8.6 1.1 2.0 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain Pro_isomerase PF00160.21 KZN92198.1 - 7.1e-44 149.9 0.1 8.4e-44 149.6 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GIT_SHD PF08518.11 KZN92199.1 - 4.4e-24 83.8 7.0 1.8e-14 53.0 0.5 2.8 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 KZN92199.1 - 4.1e-05 23.7 0.9 4.1e-05 23.7 0.9 2.3 2 0 0 2 2 2 1 G protein-coupled receptor kinase-interacting protein 1 C term CENP-F_leu_zip PF10473.9 KZN92199.1 - 0.06 13.4 25.9 0.31 11.1 13.0 2.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BRE1 PF08647.11 KZN92199.1 - 0.86 9.7 20.5 0.089 12.9 5.0 3.6 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase PspB PF06667.12 KZN92199.1 - 1.7 8.8 3.9 3.2 7.9 1.3 2.9 1 1 1 2 2 2 0 Phage shock protein B APG6_N PF17675.1 KZN92199.1 - 5 7.6 34.5 0.24 11.9 19.5 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region ZapB PF06005.12 KZN92199.1 - 8.3 6.9 31.9 7.9 7.0 2.7 4.7 1 1 3 4 4 4 0 Cell division protein ZapB TNT PF14021.6 KZN92200.1 - 0.18 12.4 0.0 0.53 10.9 0.0 1.8 2 0 0 2 2 2 0 Tuberculosis necrotizing toxin DUF3484 PF11983.8 KZN92202.1 - 0.083 14.0 0.1 0.19 12.9 0.1 1.6 1 0 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch HMG-CoA_red PF00368.18 KZN92203.1 - 1.5e-137 458.6 5.6 1.9e-137 458.2 5.6 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 KZN92203.1 - 2.7e-51 173.5 0.2 4.8e-51 172.7 0.2 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 KZN92203.1 - 4.4e-13 49.4 3.0 2.6e-12 46.8 3.0 2.2 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KZN92203.1 - 1.6e-06 26.5 1.9 1.6e-06 26.5 1.9 1.4 2 0 0 2 2 2 1 Patched family PT PF04886.12 KZN92204.1 - 0.0012 18.4 20.9 0.0013 18.2 15.8 3.3 2 0 0 2 2 2 1 PT repeat RAP1 PF07218.11 KZN92204.1 - 2.5 6.3 5.9 3.4 5.8 5.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SH3_1 PF00018.28 KZN92205.1 - 8.5e-11 41.3 0.1 1.9e-10 40.1 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KZN92205.1 - 2.5e-09 36.9 0.1 4.9e-09 35.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KZN92205.1 - 9.6e-08 31.6 0.0 1.9e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain ENTH PF01417.20 KZN92206.1 - 1.1e-44 151.5 0.2 1.6e-44 151.0 0.2 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KZN92206.1 - 0.00065 18.8 0.0 0.00093 18.3 0.0 1.2 1 0 0 1 1 1 1 ANTH domain RasGAP PF00616.19 KZN92207.1 - 7.5e-48 163.0 0.2 2.7e-47 161.2 0.0 2.1 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KZN92207.1 - 1.9e-45 154.4 4.0 1.9e-45 154.4 4.0 2.8 2 1 0 2 2 2 1 RasGAP C-terminus CH PF00307.31 KZN92207.1 - 4.4e-11 42.9 0.0 1.7e-10 41.0 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ PF00612.27 KZN92207.1 - 4.3e-07 29.2 63.6 0.94 9.5 0.0 14.7 16 0 0 16 16 16 8 IQ calmodulin-binding motif DUF952 PF06108.12 KZN92208.1 - 3.3e-19 68.7 0.0 4.2e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) adh_short_C2 PF13561.6 KZN92209.1 - 2.8e-49 167.8 0.0 3.4e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN92209.1 - 1.9e-46 158.0 0.2 2.4e-46 157.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN92209.1 - 1.5e-09 38.0 0.1 2.5e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KZN92209.1 - 0.008 15.5 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 KZN92209.1 - 0.016 14.6 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KZN92209.1 - 0.046 13.2 0.1 0.089 12.2 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family IMPDH PF00478.25 KZN92210.1 - 6.4e-130 433.2 2.0 1.3e-129 432.2 2.0 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KZN92210.1 - 1e-16 61.1 0.0 2.7e-08 34.1 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 KZN92210.1 - 1.4e-05 24.4 0.8 3.7e-05 22.9 0.4 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 KZN92210.1 - 0.00014 21.4 7.8 0.064 12.6 5.5 2.6 2 1 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 KZN92210.1 - 0.0014 18.1 3.4 0.038 13.5 0.3 2.3 1 1 1 2 2 2 2 Histidine biosynthesis protein PK PF00224.21 KZN92210.1 - 0.021 13.7 0.0 0.066 12.1 0.0 1.7 1 1 1 2 2 2 0 Pyruvate kinase, barrel domain Aldolase PF01081.19 KZN92210.1 - 0.023 14.1 0.8 0.11 11.9 0.1 2.3 2 0 0 2 2 2 0 KDPG and KHG aldolase YpsA PF06908.11 KZN92210.1 - 0.063 13.3 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family NUDIX PF00293.28 KZN92211.1 - 3e-07 30.6 0.0 1.2e-06 28.6 0.0 2.1 1 1 1 2 2 2 1 NUDIX domain NAD_binding_9 PF13454.6 KZN92211.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Ribosomal_S21e PF01249.18 KZN92212.1 - 1e-41 140.9 0.0 1.1e-41 140.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e tRNA-synt_2d PF01409.20 KZN92213.1 - 9.5e-88 293.8 0.0 1.5e-87 293.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KZN92213.1 - 5e-15 55.5 1.6 5.4e-15 55.4 0.3 1.8 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 KZN92213.1 - 2.3e-08 33.7 0.0 4.7e-07 29.5 0.0 2.2 1 1 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD2 PF18554.1 KZN92213.1 - 8.4e-05 22.5 5.7 0.0003 20.7 5.7 2.0 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_2 PF00152.20 KZN92213.1 - 0.00027 20.1 0.1 0.014 14.5 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) Androgen_recep PF02166.16 KZN92213.1 - 0.011 14.7 1.4 0.017 14.0 1.4 1.2 1 0 0 1 1 1 0 Androgen receptor HAMP PF00672.25 KZN92214.1 - 1.6e-43 146.9 14.5 1.3e-08 35.0 0.4 7.2 6 0 0 6 6 6 5 HAMP domain HATPase_c PF02518.26 KZN92214.1 - 9.2e-33 113.1 0.2 3.5e-32 111.2 0.2 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KZN92214.1 - 3.8e-26 91.5 0.6 1.9e-25 89.2 0.6 2.3 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KZN92214.1 - 7.9e-17 61.1 3.3 3.1e-16 59.2 0.2 3.7 4 0 0 4 4 3 1 His Kinase A (phospho-acceptor) domain APG17 PF04108.12 KZN92214.1 - 2.1e-14 53.5 7.0 0.011 14.9 0.0 5.9 1 1 2 4 4 4 3 Autophagy protein Apg17 Syntaxin_2 PF14523.6 KZN92214.1 - 3.3e-06 27.4 20.7 1.1 9.6 0.1 7.4 3 2 2 6 6 6 2 Syntaxin-like protein DUF4279 PF14106.6 KZN92214.1 - 0.00034 20.8 0.7 7.8 6.7 0.0 5.6 6 1 0 6 6 6 1 Domain of unknown function (DUF4279) DUF1843 PF08898.10 KZN92214.1 - 0.0012 19.3 7.2 16 6.1 0.1 6.0 5 1 0 5 5 5 0 Domain of unknown function (DUF1843) DUF948 PF06103.11 KZN92214.1 - 0.005 17.1 57.4 1.1 9.6 0.2 10.1 4 2 2 6 6 5 3 Bacterial protein of unknown function (DUF948) Gp-FAR-1 PF05823.12 KZN92214.1 - 0.013 15.8 5.8 20 5.5 0.1 5.0 1 1 2 5 5 5 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Fib_alpha PF08702.10 KZN92214.1 - 0.026 14.7 33.9 1.2 9.4 0.6 7.5 6 1 1 7 7 7 0 Fibrinogen alpha/beta chain family SpoIIID PF12116.8 KZN92214.1 - 0.033 14.3 4.8 23 5.1 0.0 5.3 5 0 0 5 5 5 0 Stage III sporulation protein D NOD PF06816.13 KZN92214.1 - 0.048 13.3 0.0 6.4 6.5 0.0 2.7 2 0 0 2 2 2 0 NOTCH protein Cbl_N PF02262.16 KZN92214.1 - 0.068 13.2 0.1 3.6 7.6 0.1 2.9 2 0 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 CMD PF02627.20 KZN92214.1 - 0.14 12.2 1.1 17 5.6 0.0 4.0 5 0 0 5 5 4 0 Carboxymuconolactone decarboxylase family DUF3829 PF12889.7 KZN92214.1 - 0.2 11.1 18.6 0.35 10.3 0.8 5.3 3 3 2 6 6 6 0 Protein of unknown function (DUF3829) WXG100 PF06013.12 KZN92214.1 - 1 9.7 30.7 2 8.7 0.3 8.5 6 2 4 10 10 10 0 Proteins of 100 residues with WXG GLE1 PF07817.13 KZN92214.1 - 3.4 6.8 12.7 8 5.6 0.7 4.6 3 1 2 5 5 5 0 GLE1-like protein Mer2 PF09074.10 KZN92214.1 - 5.6 6.7 37.3 3.2 7.5 3.6 6.0 3 1 3 6 6 6 0 Mer2 APG6_N PF17675.1 KZN92214.1 - 5.7 7.5 12.1 53 4.3 7.1 4.0 3 0 0 3 3 3 0 Apg6 coiled-coil region Phage_Mu_Gam PF07352.12 KZN92214.1 - 5.8 6.8 17.5 6.9 6.6 0.2 5.6 5 1 1 6 6 6 0 Bacteriophage Mu Gam like protein Ribosomal_L24e PF01246.20 KZN92215.1 - 4.9e-28 97.2 5.8 4.9e-28 97.2 5.8 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e Pam16 PF03656.13 KZN92216.1 - 7.2e-08 32.5 0.1 1.4e-07 31.6 0.1 1.6 1 1 0 1 1 1 1 Pam16 DnaJ PF00226.31 KZN92216.1 - 1.3e-05 25.2 0.1 2e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain DUF3918 PF13056.6 KZN92216.1 - 0.46 10.1 3.5 0.41 10.3 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) Fungal_trans PF04082.18 KZN92217.1 - 3.7e-23 81.9 0.0 1.4e-22 80.0 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN92217.1 - 8.7e-10 38.6 13.1 1.4e-09 37.9 13.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATP11 PF06644.11 KZN92217.1 - 7.1 6.3 7.0 0.48 10.2 0.4 2.0 2 0 0 2 2 2 0 ATP11 protein Peptidase_M41 PF01434.18 KZN92218.1 - 2e-66 223.5 0.0 3.5e-66 222.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KZN92218.1 - 1.6e-42 145.0 0.0 3.5e-42 143.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KZN92218.1 - 1.2e-12 47.4 0.1 2.8e-12 46.2 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KZN92218.1 - 1.7e-12 47.6 0.0 4.4e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 KZN92218.1 - 0.00055 19.9 0.0 0.0023 17.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KZN92218.1 - 0.0032 17.9 0.0 0.21 12.0 0.1 2.9 3 0 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KZN92218.1 - 0.0073 16.1 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KZN92218.1 - 0.01 15.1 0.4 0.021 14.0 0.1 1.6 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_22 PF13401.6 KZN92218.1 - 0.015 15.5 0.1 1.2 9.4 0.1 2.9 3 0 0 3 3 3 0 AAA domain AAA_2 PF07724.14 KZN92218.1 - 0.031 14.4 0.0 0.14 12.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KZN92218.1 - 0.031 14.0 0.0 0.17 11.6 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF1155 PF06633.11 KZN92218.1 - 0.035 13.6 0.1 0.081 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1155) RR_TM4-6 PF06459.12 KZN92218.1 - 0.14 12.0 8.8 0.27 11.0 8.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 KZN92218.1 - 0.23 9.7 10.8 0.34 9.2 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KZN92218.1 - 0.35 9.6 6.8 0.57 8.9 6.8 1.2 1 0 0 1 1 1 0 Presenilin DUF2201_N PF13203.6 KZN92218.1 - 0.68 9.5 7.0 1.2 8.7 7.0 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain GAGA_bind PF06217.12 KZN92218.1 - 0.73 10.1 9.0 1.2 9.4 9.0 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family SAPS PF04499.15 KZN92218.1 - 1.1 8.0 4.3 1.6 7.5 4.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1295 PF06966.12 KZN92219.1 - 1.4e-39 136.0 7.2 1.8e-39 135.7 7.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Topoisom_bac PF01131.20 KZN92220.1 - 2.5e-101 339.7 0.0 3.2e-101 339.3 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 KZN92220.1 - 8.4e-18 64.5 0.0 3.3e-17 62.6 0.0 2.0 2 0 0 2 2 2 1 Toprim domain Toprim_4 PF13662.6 KZN92220.1 - 0.075 13.5 0.0 2.2 8.8 0.0 2.6 2 0 0 2 2 2 0 Toprim domain Ribosomal_S4Pg PF11993.8 KZN92221.1 - 0.034 14.2 0.1 0.066 13.3 0.1 1.4 1 0 0 1 1 1 0 Ribosomal S4P (gammaproteobacterial) Glyco_hydro_28 PF00295.17 KZN92224.1 - 1.2e-35 123.1 11.3 1.9e-31 109.3 6.4 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KZN92224.1 - 0.00037 20.4 10.3 0.00037 20.4 10.3 2.6 2 1 0 2 2 2 1 Right handed beta helix region Glyco_hydro_7 PF00840.20 KZN92225.1 - 5.1e-210 697.7 12.8 5.8e-210 697.5 12.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 ANAPC4_WD40 PF12894.7 KZN92226.1 - 1.5e-05 25.2 0.0 0.027 14.8 0.0 2.7 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 KZN92226.1 - 0.12 11.6 0.0 12 5.0 0.0 2.5 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40 PF00400.32 KZN92226.1 - 0.25 12.3 6.5 6.5 7.8 0.1 4.7 5 0 0 5 5 5 0 WD domain, G-beta repeat YL1 PF05764.13 KZN92226.1 - 1.8 8.7 10.3 3.4 7.7 10.3 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Bromodomain PF00439.25 KZN92227.1 - 6e-20 71.1 0.1 1e-19 70.3 0.1 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KZN92227.1 - 5.2e-08 33.1 0.0 9.5e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KZN92227.1 - 8.6e-07 28.9 0.0 1.7e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KZN92227.1 - 0.00018 21.8 0.3 0.00041 20.7 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain MgtE PF01769.16 KZN92228.1 - 0.095 13.1 0.1 0.095 13.1 0.1 2.5 1 1 1 2 2 2 0 Divalent cation transporter FAD_binding_4 PF01565.23 KZN92229.1 - 2.4e-21 75.9 4.8 6.1e-21 74.6 4.8 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KZN92229.1 - 4.2e-07 30.0 0.0 8.5e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF3969 PF13108.6 KZN92229.1 - 0.11 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3969) Fe-ADH PF00465.19 KZN92230.1 - 1.3e-77 261.1 0.5 1.5e-77 260.9 0.5 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KZN92230.1 - 2.7e-15 56.8 0.4 3.7e-15 56.3 0.4 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase IMS_C PF11799.8 KZN92230.1 - 0.026 15.2 0.0 0.29 11.9 0.0 2.3 1 1 0 1 1 1 0 impB/mucB/samB family C-terminal domain Diphthamide_syn PF01866.17 KZN92231.1 - 1.4e-86 290.7 0.0 2.7e-86 289.7 0.0 1.5 1 1 0 1 1 1 1 Putative diphthamide synthesis protein CS PF04969.16 KZN92234.1 - 1.6e-17 64.3 0.0 2.8e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 CS domain Zn_clus PF00172.18 KZN92235.1 - 3.6e-10 39.8 10.3 7.3e-10 38.8 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KZN92235.1 - 0.0019 17.1 0.3 0.0019 17.1 0.3 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain FAM70 PF14967.6 KZN92236.1 - 6.2 6.2 8.5 8.4 5.8 8.5 1.2 1 0 0 1 1 1 0 FAM70 protein Methyltransf_12 PF08242.12 KZN92237.1 - 5.1e-15 56.0 0.0 2.6e-14 53.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN92237.1 - 6.1e-13 49.3 0.0 1.6e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN92237.1 - 7.4e-12 45.4 0.0 1.2e-11 44.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN92237.1 - 5.6e-11 42.9 0.0 1.5e-10 41.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN92237.1 - 4e-07 29.9 0.0 9.5e-07 28.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KZN92237.1 - 5.2e-07 29.2 0.0 8.6e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 KZN92237.1 - 0.00031 20.7 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 2 Hypothetical methyltransferase DUF3419 PF11899.8 KZN92237.1 - 0.0007 18.9 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) MTS PF05175.14 KZN92237.1 - 0.0062 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 KZN92237.1 - 0.016 16.2 0.0 0.1 13.7 0.0 2.2 3 0 0 3 3 3 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KZN92237.1 - 0.046 12.9 0.0 0.69 9.1 0.0 2.1 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_32 PF13679.6 KZN92237.1 - 0.089 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain HlyIII PF03006.20 KZN92238.1 - 4.2e-61 206.5 23.7 5.2e-61 206.2 23.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related SPC12 PF06645.13 KZN92238.1 - 0.005 16.9 0.4 0.005 16.9 0.4 2.7 2 1 1 3 3 3 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Asr PF06392.11 KZN92238.1 - 0.0061 16.9 0.6 0.017 15.5 0.6 1.7 1 0 0 1 1 1 1 Acid shock protein repeat FmiP_Thoc5 PF09766.9 KZN92239.1 - 1.6e-31 110.0 14.0 1.9e-31 109.7 14.0 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 SPATA1_C PF15743.5 KZN92239.1 - 0.0033 17.5 6.7 0.011 15.9 3.3 2.2 2 0 0 2 2 2 1 Spermatogenesis-associated C-terminus Rootletin PF15035.6 KZN92239.1 - 0.041 13.9 11.0 0.049 13.6 11.0 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion RNase_E_G PF10150.9 KZN92239.1 - 0.045 13.2 6.3 0.73 9.2 1.7 2.1 2 0 0 2 2 2 0 Ribonuclease E/G family DUF4200 PF13863.6 KZN92239.1 - 0.15 12.4 15.2 0.45 10.9 1.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) CwfJ_C_1 PF04677.15 KZN92239.1 - 0.15 11.9 1.0 0.52 10.2 0.3 1.9 1 1 1 2 2 2 0 Protein similar to CwfJ C-terminus 1 DUF2353 PF09789.9 KZN92239.1 - 0.26 10.6 15.6 2 7.7 15.6 1.9 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Mod_r PF07200.13 KZN92239.1 - 0.65 10.1 15.4 0.98 9.5 4.3 2.4 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein YabA PF06156.13 KZN92239.1 - 0.71 10.5 7.2 8.9 7.0 0.2 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Casc1_N PF15927.5 KZN92239.1 - 0.92 9.2 13.4 0.084 12.5 8.5 1.8 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus PIG-S PF10510.9 KZN92240.1 - 6.4e-189 629.1 0.1 7.4e-189 628.8 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Sporozoite_P67 PF05642.11 KZN92241.1 - 7 4.6 10.1 9.1 4.2 10.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sod_Fe_C PF02777.18 KZN92242.1 - 3.8e-17 62.3 0.0 2.6e-10 40.4 0.2 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KZN92242.1 - 0.036 14.5 0.1 0.06 13.8 0.1 1.4 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Polyketide_cyc PF03364.20 KZN92243.1 - 4.5e-23 81.9 0.0 1.9e-22 79.9 0.0 1.9 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KZN92243.1 - 0.00055 20.2 0.1 0.007 16.6 0.1 2.1 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Fungal_trans PF04082.18 KZN92244.1 - 1.9e-13 50.1 1.4 3.3e-13 49.3 1.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN92244.1 - 1.1e-05 25.4 13.2 1.1e-05 25.4 13.2 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain U71 PF17474.2 KZN92244.1 - 5 7.1 5.1 11 6.0 5.1 1.5 1 0 0 1 1 1 0 Tegument protein UL11 homolog Aldo_ket_red PF00248.21 KZN92246.1 - 5.7e-49 166.9 0.0 6.4e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family IcmF_C PF06744.12 KZN92246.1 - 0.17 11.5 0.0 0.47 10.0 0.0 1.7 1 1 0 1 1 1 0 Type VI secretion protein IcmF C-terminal AMP-binding PF00501.28 KZN92247.1 - 1.6e-62 211.5 0.0 2.2e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KZN92247.1 - 3.8e-05 24.6 0.0 7.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aminotran_1_2 PF00155.21 KZN92248.1 - 1.1e-44 153.2 0.0 1.3e-44 152.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KZN92248.1 - 3.9e-07 29.3 0.0 9e-07 28.2 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KZN92248.1 - 2e-05 24.0 0.0 3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KZN92248.1 - 5.1e-05 22.0 0.0 7.2e-05 21.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KZN92248.1 - 0.06 12.6 0.0 0.091 12.0 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family ABC2_membrane PF01061.24 KZN92249.1 - 4.2e-37 127.6 20.8 8.3e-37 126.6 20.8 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KZN92249.1 - 4.7e-23 82.2 1.9 6.3e-23 81.8 0.1 2.0 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KZN92249.1 - 1.9e-05 24.7 0.0 0.16 11.7 0.1 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KZN92249.1 - 0.016 14.3 28.3 0.0055 15.9 24.7 1.8 1 1 1 2 2 2 0 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KZN92249.1 - 0.02 14.8 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase SMC_N PF02463.19 KZN92249.1 - 0.048 13.1 0.9 1 8.7 0.0 2.6 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KZN92249.1 - 0.056 13.2 0.2 0.13 12.0 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KZN92249.1 - 0.15 12.4 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KZN92249.1 - 0.24 11.9 0.9 0.63 10.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain Laminin_EGF PF00053.24 KZN92249.1 - 3.2 8.0 29.2 1.1 9.4 7.9 3.7 2 1 1 3 3 3 0 Laminin EGF domain Cornichon PF03311.14 KZN92250.1 - 6.8e-49 165.3 13.9 7.7e-49 165.1 13.9 1.0 1 0 0 1 1 1 1 Cornichon protein WD40 PF00400.32 KZN92251.1 - 1.9e-32 110.8 7.3 2.8e-08 34.3 0.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN92251.1 - 5.3e-16 58.7 0.0 6e-06 26.5 0.0 5.0 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KZN92251.1 - 0.00012 21.7 0.0 0.00044 19.9 0.0 2.0 1 1 0 1 1 1 1 PQQ-like domain COX_ARM PF06481.14 KZN92251.1 - 0.15 12.0 0.7 0.3 11.0 0.1 1.8 2 0 0 2 2 2 0 COX Aromatic Rich Motif FAD_binding_3 PF01494.19 KZN92252.1 - 6.3e-19 68.4 0.0 1.1e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KZN92252.1 - 2.7e-05 23.5 0.0 5.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KZN92252.1 - 0.00072 18.7 0.0 0.0019 17.4 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KZN92252.1 - 0.0022 18.5 0.0 0.0098 16.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KZN92252.1 - 0.0024 16.6 0.1 0.0037 16.0 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 KZN92252.1 - 0.0041 16.8 0.1 0.0092 15.6 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KZN92252.1 - 0.0061 16.8 0.2 0.022 15.0 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KZN92252.1 - 0.0066 15.8 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KZN92252.1 - 0.018 14.4 0.5 0.058 12.7 0.4 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KZN92252.1 - 0.24 11.3 0.0 0.49 10.2 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_M24 PF00557.24 KZN92253.1 - 4.6e-48 163.7 0.0 5.6e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KZN92253.1 - 3.3e-19 68.9 7.9 7.9e-19 67.7 7.9 1.7 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KZN92253.1 - 0.0024 17.9 5.9 0.0024 17.9 5.9 2.3 2 0 0 2 2 2 1 MYND finger MFS_1 PF07690.16 KZN92254.1 - 1.8e-45 155.4 54.8 1.8e-45 155.4 54.8 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN92254.1 - 4.5e-14 52.2 10.3 4.5e-14 52.2 10.3 3.4 4 0 0 4 4 4 1 Sugar (and other) transporter EF-hand_1 PF00036.32 KZN92255.1 - 3.7e-12 44.9 3.0 5.4e-05 22.4 0.2 3.4 3 0 0 3 3 3 2 EF hand ZZ PF00569.17 KZN92255.1 - 4.9e-12 45.5 4.2 8.2e-12 44.7 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_7 PF13499.6 KZN92255.1 - 4.9e-11 42.9 6.2 9.1e-08 32.4 1.5 3.0 3 1 2 5 5 5 3 EF-hand domain pair EF-hand_6 PF13405.6 KZN92255.1 - 1.4e-09 37.1 2.2 0.00018 21.2 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KZN92255.1 - 4.1e-05 23.3 3.6 0.16 11.8 0.1 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KZN92255.1 - 4.6e-05 22.7 1.7 0.12 12.0 0.2 2.9 2 0 0 2 2 2 2 EF hand C1_2 PF03107.16 KZN92255.1 - 0.0071 16.6 3.8 0.013 15.8 3.8 1.4 1 0 0 1 1 1 1 C1 domain DUF4614 PF15391.6 KZN92255.1 - 2.9 7.9 4.4 4.9 7.1 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4614) UNC-93 PF05978.16 KZN92256.1 - 4e-16 59.1 2.0 4e-16 59.1 2.0 2.8 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KZN92256.1 - 2.7e-14 52.9 20.3 2.7e-14 52.9 20.3 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KZN92256.1 - 0.1 10.9 5.9 0.063 11.6 0.7 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family 3Beta_HSD PF01073.19 KZN92257.1 - 4.4e-50 170.3 0.0 5.3e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KZN92257.1 - 3.5e-39 134.7 0.0 4.3e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KZN92257.1 - 1.5e-19 70.6 0.0 3.5e-19 69.4 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KZN92257.1 - 3.6e-15 55.8 0.0 4.7e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KZN92257.1 - 1.4e-13 50.6 0.0 1.2e-09 37.7 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KZN92257.1 - 2.9e-10 40.3 0.0 4.2e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KZN92257.1 - 4e-10 39.3 0.0 2.5e-09 36.7 0.0 2.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 KZN92257.1 - 7.6e-05 22.7 0.0 0.00033 20.6 0.0 1.9 1 1 0 1 1 1 1 KR domain TrkA_N PF02254.18 KZN92257.1 - 8.2e-05 22.8 0.0 0.00016 21.9 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.25 KZN92257.1 - 0.00016 21.2 0.0 0.00043 19.8 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 KZN92257.1 - 0.00017 21.8 0.0 0.00055 20.2 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain adh_short_C2 PF13561.6 KZN92257.1 - 0.00079 19.0 0.0 0.0015 18.2 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Semialdhyde_dh PF01118.24 KZN92257.1 - 0.0085 16.5 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 KZN92257.1 - 0.014 14.9 0.0 0.028 14.0 0.0 1.5 1 1 0 1 1 1 0 NmrA-like family DUF1132 PF06575.12 KZN92257.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) NAD_binding_3 PF03447.16 KZN92257.1 - 0.16 12.6 0.0 0.3 11.8 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Cut8 PF08559.10 KZN92258.1 - 0.079 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein Ribosomal_S7 PF00177.21 KZN92258.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e SDA1 PF05285.12 KZN92258.1 - 9.7 5.5 9.4 13 5.1 9.4 1.1 1 0 0 1 1 1 0 SDA1 Ribosomal_S8 PF00410.19 KZN92260.1 - 1.6e-14 53.9 0.0 1.3e-13 51.1 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S8 Iso_dh PF00180.20 KZN92263.1 - 6.2e-98 328.1 0.0 9.6e-98 327.5 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1769 PF08588.10 KZN92264.1 - 9.3e-28 96.2 0.2 5.6e-27 93.7 0.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) Beta-lactamase PF00144.24 KZN92266.1 - 8.8e-60 202.7 0.2 1.1e-59 202.4 0.2 1.0 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KZN92266.1 - 0.0015 18.1 0.0 0.0057 16.3 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase enzyme family Peptidase_S11 PF00768.20 KZN92266.1 - 0.0031 17.0 0.3 0.042 13.3 0.1 2.1 2 0 0 2 2 2 1 D-alanyl-D-alanine carboxypeptidase Microvir_J PF04726.13 KZN92266.1 - 0.19 11.7 0.1 0.36 10.8 0.1 1.4 1 0 0 1 1 1 0 Microvirus J protein CENP-F_leu_zip PF10473.9 KZN92267.1 - 2.7e-05 24.2 33.2 0.015 15.4 9.4 4.7 4 1 0 4 4 4 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 KZN92267.1 - 0.0032 17.6 5.9 0.0032 17.6 5.9 4.5 2 1 3 5 5 5 2 Afadin- and alpha -actinin-Binding Sec3_C_2 PF15278.6 KZN92267.1 - 0.026 14.8 0.1 0.093 13.1 0.1 2.0 1 0 0 1 1 1 0 Sec3 exocyst complex subunit GIT_CC PF16559.5 KZN92267.1 - 0.083 12.8 2.6 33 4.4 0.1 3.9 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Transposase_1 PF01359.18 KZN92267.1 - 0.12 12.3 0.3 0.35 10.7 0.2 2.0 2 0 0 2 2 2 0 Transposase (partial DDE domain) E2R135 PF11570.8 KZN92267.1 - 0.53 10.6 4.0 5.4 7.3 0.1 3.0 3 0 0 3 3 3 0 Coiled-coil receptor-binding R-domain of colicin E2 GAS PF13851.6 KZN92267.1 - 0.67 9.3 30.4 2.4 7.4 16.1 3.9 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding KLRAQ PF10205.9 KZN92267.1 - 0.77 10.0 21.7 1.1 9.6 6.5 4.5 3 1 3 6 6 6 0 Predicted coiled-coil domain-containing protein MatP_C PF17414.2 KZN92267.1 - 0.96 9.7 4.3 21 5.4 0.2 2.9 2 0 0 2 2 2 0 MatP C-terminal ribbon-helix-helix domain Tup_N PF08581.10 KZN92267.1 - 1 9.7 24.8 0.88 9.9 0.9 4.6 5 0 0 5 5 5 0 Tup N-terminal Fib_alpha PF08702.10 KZN92267.1 - 7.5 6.7 24.1 0.78 9.9 5.1 4.4 3 1 2 5 5 5 0 Fibrinogen alpha/beta chain family SHE3 PF17078.5 KZN92267.1 - 9.6 5.8 26.0 0.14 11.8 9.8 3.5 2 1 1 3 3 3 0 SWI5-dependent HO expression protein 3 DUF3506 PF12014.8 KZN92268.1 - 1.7e-55 186.9 0.0 2.7e-55 186.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 KZN92268.1 - 3.8e-09 36.3 0.1 7e-09 35.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN92268.1 - 0.0022 17.8 0.0 0.0045 16.8 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KZN92268.1 - 0.0059 16.5 0.2 0.076 12.9 0.0 2.2 2 0 0 2 2 2 1 F-box 2OG-FeII_Oxy PF03171.20 KZN92269.1 - 4.3e-19 68.9 0.0 1.1e-18 67.6 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KZN92269.1 - 1.6e-17 64.3 0.0 3.1e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal PI3K_p85B PF02192.16 KZN92270.1 - 0.069 12.9 0.0 0.3 10.8 0.0 1.9 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain DUF1748 PF08520.10 KZN92273.1 - 2.1e-28 98.0 0.1 2.4e-28 97.8 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) PK PF00224.21 KZN92274.1 - 3.9e-173 575.2 3.1 4.9e-173 574.9 3.1 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KZN92274.1 - 4.7e-39 133.2 0.0 1.5e-38 131.6 0.0 1.9 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KZN92274.1 - 0.00032 19.9 0.4 0.00091 18.4 0.2 1.7 1 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 KZN92274.1 - 0.072 12.1 0.1 0.62 9.0 0.0 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Methyltransf_2 PF00891.18 KZN92275.1 - 4e-27 94.9 0.0 8e-27 93.9 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KZN92275.1 - 0.00028 20.8 0.0 0.0021 18.0 0.0 2.2 2 0 0 2 2 2 1 Dimerisation domain DUF4423 PF14394.6 KZN92275.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) Rrf2 PF02082.20 KZN92275.1 - 0.14 12.5 0.0 0.45 10.9 0.0 1.7 2 0 0 2 2 2 0 Transcriptional regulator PIP5K PF01504.18 KZN92277.1 - 4.9e-33 114.5 0.0 3.6e-25 88.7 0.1 2.6 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KZN92277.1 - 3.1e-27 95.3 0.0 4.9e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KZN92277.1 - 1.8e-14 53.6 5.4 1.8e-14 53.6 5.4 1.9 2 0 0 2 2 2 1 FYVE zinc finger C1_1 PF00130.22 KZN92277.1 - 0.14 12.1 7.9 0.029 14.3 4.0 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SUR7 PF06687.12 KZN92279.1 - 8.7e-50 169.3 12.9 1.1e-49 169.0 12.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF3742 PF12553.8 KZN92279.1 - 1.6 8.9 8.5 1.6 8.9 1.5 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3742) DUF4191 PF13829.6 KZN92279.1 - 3.9 6.8 4.9 6 6.1 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Dala_Dala_lig_C PF07478.13 KZN92282.1 - 4.7e-26 91.6 0.0 7.3e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus GARS_A PF01071.19 KZN92282.1 - 0.00038 20.3 0.0 0.00058 19.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.6 KZN92282.1 - 0.00053 19.6 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KZN92282.1 - 0.0008 19.5 0.1 0.0014 18.7 0.1 1.6 1 1 0 1 1 1 1 ATP-grasp domain STAT6_C PF14596.6 KZN92282.1 - 0.0012 18.9 0.1 0.0026 17.8 0.1 1.5 1 0 0 1 1 1 1 STAT6 C-terminal ATP-grasp PF02222.22 KZN92282.1 - 0.18 11.4 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain Cellulase PF00150.18 KZN92283.1 - 3e-55 187.6 2.6 4e-55 187.2 2.6 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Lipase_GDSL_2 PF13472.6 KZN92284.1 - 2.1e-05 25.0 3.3 3.4e-05 24.3 3.3 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KZN92284.1 - 0.00097 19.2 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase WD40 PF00400.32 KZN92285.1 - 1.3e-15 57.5 28.7 7.8e-06 26.5 1.5 10.9 10 0 0 10 10 10 4 WD domain, G-beta repeat DUF281 PF03436.13 KZN92285.1 - 0.12 12.8 0.1 0.51 10.8 0.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF281) MctB PF11382.8 KZN92285.1 - 0.26 10.9 4.3 0.53 9.9 4.3 1.4 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB XPG_N PF00752.17 KZN92286.1 - 3.6e-35 120.5 0.2 2.3e-34 117.9 0.0 2.5 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 KZN92286.1 - 2.6e-25 88.6 1.5 6.9e-25 87.2 0.0 2.4 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 KZN92286.1 - 2.1e-05 25.1 0.0 0.00013 22.4 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold UIM PF02809.20 KZN92286.1 - 0.00024 20.8 0.3 0.0019 18.0 0.3 2.8 1 0 0 1 1 1 1 Ubiquitin interaction motif HHH_5 PF14520.6 KZN92286.1 - 0.018 15.7 0.0 0.046 14.3 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain Transposase_20 PF02371.16 KZN92286.1 - 0.036 14.4 0.0 0.091 13.1 0.0 1.6 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family TSC22 PF01166.18 KZN92288.1 - 0.0019 18.4 0.2 0.0048 17.2 0.2 1.6 1 0 0 1 1 1 1 TSC-22/dip/bun family Pil1 PF13805.6 KZN92289.1 - 3.2e-123 410.4 0.1 4e-123 410.1 0.1 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 APG6_N PF17675.1 KZN92289.1 - 2.5 8.6 5.8 23 5.5 0.1 2.7 2 1 0 2 2 2 0 Apg6 coiled-coil region bZIP_2 PF07716.15 KZN92290.1 - 9.7e-14 51.2 12.9 1.6e-13 50.5 12.9 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KZN92290.1 - 0.00039 20.5 11.8 0.00077 19.5 11.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor DUF4094 PF13334.6 KZN92290.1 - 0.022 15.2 0.3 0.036 14.5 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) SIKE PF05769.11 KZN92290.1 - 0.022 14.7 1.5 0.031 14.2 1.5 1.1 1 0 0 1 1 1 0 SIKE family TSC22 PF01166.18 KZN92290.1 - 0.12 12.7 0.6 0.24 11.8 0.6 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF3552 PF12072.8 KZN92290.1 - 0.14 11.5 8.1 0.19 11.1 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) FPP PF05911.11 KZN92290.1 - 0.16 10.2 5.4 0.21 9.8 5.4 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Fungal_trans PF04082.18 KZN92291.1 - 9e-22 77.4 0.4 1.6e-21 76.5 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN92291.1 - 0.00026 21.0 10.7 0.00045 20.3 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TTSSLRR PF12468.8 KZN92291.1 - 0.045 14.0 0.1 0.16 12.2 0.1 1.9 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein Spc7_N PF15402.6 KZN92292.1 - 0 1082.0 76.7 8e-205 683.0 44.3 3.0 1 1 2 3 3 3 2 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 KZN92292.1 - 4.4e-127 423.2 5.7 8.7e-127 422.3 5.7 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein PTS_IIB PF02302.17 KZN92292.1 - 0.18 12.5 0.4 0.63 10.8 0.4 1.9 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIB subunit FapA PF03961.13 KZN92292.1 - 0.48 9.0 5.3 1.1 7.7 5.3 1.6 1 0 0 1 1 1 0 Flagellar Assembly Protein A Atg14 PF10186.9 KZN92292.1 - 0.6 9.1 15.3 0.013 14.6 7.2 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 KZN92292.1 - 7.2 5.9 12.5 0.44 9.8 4.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Ribosomal_S17_N PF16205.5 KZN92293.1 - 5.6e-34 116.4 0.7 1.1e-33 115.5 0.7 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KZN92293.1 - 8.1e-28 96.3 1.0 1.8e-27 95.2 1.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S17 MIB_HERC2 PF06701.13 KZN92294.1 - 0.011 16.0 0.1 0.062 13.6 0.1 2.5 1 0 0 1 1 1 0 Mib_herc2 ANTH PF07651.16 KZN92295.1 - 3e-58 197.0 0.0 3.9e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KZN92295.1 - 2e-07 31.1 0.0 1.1e-06 28.7 0.0 2.0 2 0 0 2 2 2 1 ENTH domain Fungal_trans_2 PF11951.8 KZN92296.1 - 4.9e-13 48.6 0.0 2e-12 46.6 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain FAM199X PF15814.5 KZN92296.1 - 0.098 11.7 0.3 0.16 11.0 0.3 1.3 1 0 0 1 1 1 0 Protein family FAM199X Gpr1_Fun34_YaaH PF01184.19 KZN92297.1 - 5.2e-89 297.3 18.3 6.3e-89 297.1 18.3 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Oxidored_FMN PF00724.20 KZN92298.1 - 9.6e-95 317.7 0.0 1.1e-94 317.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 KZN92298.1 - 0.095 12.1 0.0 11 5.3 0.0 2.8 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel OxoDH_E1alpha_N PF12573.8 KZN92299.1 - 4.2 7.2 16.5 4.2 7.2 0.9 4.5 3 0 0 3 3 3 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal WD40 PF00400.32 KZN92301.1 - 2.9e-20 72.2 12.2 0.00019 22.2 0.1 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN92301.1 - 4.6e-17 62.1 0.0 7.8e-07 29.3 0.0 5.5 3 1 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KZN92301.1 - 1.8e-05 24.7 0.5 0.017 15.0 0.0 2.6 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KZN92301.1 - 0.001 18.1 0.1 9.6 5.0 0.0 3.9 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein HIRA_B PF09453.10 KZN92301.1 - 0.0023 17.7 0.3 0.0023 17.7 0.3 2.6 2 0 0 2 2 2 1 HIRA B motif PD40 PF07676.12 KZN92301.1 - 0.051 13.5 5.8 8.1 6.5 0.2 4.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KZN92301.1 - 0.076 12.3 0.0 1.7 7.9 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain Glyco_transf_20 PF00982.21 KZN92302.1 - 2e-140 468.7 0.0 5.1e-140 467.3 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KZN92302.1 - 5e-29 101.1 0.0 1.1e-28 100.0 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase Rad4 PF03835.15 KZN92303.1 - 5.5e-14 52.1 3.5 9.6e-14 51.3 3.5 1.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 KZN92303.1 - 1e-11 45.2 2.1 2.6e-11 44.0 2.1 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Glyco_hydro_71 PF03659.14 KZN92305.1 - 1.2e-123 412.7 0.7 1.4e-123 412.5 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.6 KZN92305.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Memo PF01875.17 KZN92306.1 - 3.2e-66 223.2 0.0 3.8e-66 223.0 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein IPTL-CTERM PF18203.1 KZN92307.1 - 0.25 11.3 0.3 0.25 11.3 0.3 1.9 2 0 0 2 2 2 0 IPTL-CTERM motif LSM PF01423.22 KZN92308.1 - 1.8e-07 30.7 0.0 2.4e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KZN92308.1 - 0.0024 17.9 0.0 0.0048 17.0 0.0 1.7 1 1 0 1 1 1 1 Ataxin 2 SM domain DUF2380 PF09533.10 KZN92308.1 - 0.091 12.4 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) Metallophos PF00149.28 KZN92309.1 - 2.6e-37 129.3 0.1 4e-37 128.7 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KZN92309.1 - 4.4e-18 65.4 0.0 8.1e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain AOX PF01786.17 KZN92310.1 - 1.1e-92 309.5 0.2 1.4e-92 309.1 0.2 1.1 1 0 0 1 1 1 1 Alternative oxidase DUF3435 PF11917.8 KZN92311.1 - 2.7e-74 250.6 0.6 4.3e-74 249.9 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) DUF4763 PF15960.5 KZN92311.1 - 0.038 13.3 0.2 0.087 12.1 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) DUF883 PF05957.13 KZN92311.1 - 6.1 7.5 9.9 0.12 13.0 1.0 2.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) T4_Gp59_C PF08994.10 KZN92313.1 - 0.097 13.3 0.1 0.21 12.2 0.1 1.5 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term Rrn6 PF10214.9 KZN92316.1 - 0.088 11.3 2.6 0.12 10.8 2.6 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor APH PF01636.23 KZN92318.1 - 7e-06 26.1 0.3 0.0021 18.1 0.1 2.9 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KZN92318.1 - 0.0013 18.1 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KZN92318.1 - 0.013 14.9 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain UPF0688 PF15772.5 KZN92318.1 - 0.58 10.4 8.7 0.036 14.3 2.8 1.9 2 0 0 2 2 2 0 UPF0688 family PARM PF17061.5 KZN92318.1 - 3.4 7.7 14.4 6.7 6.8 14.4 1.4 1 0 0 1 1 1 0 PARM CENP-R PF06729.12 KZN92319.1 - 0.08 12.9 0.2 0.08 12.9 0.2 2.7 3 0 0 3 3 3 0 Kinetochore component, CENP-R NUDIX PF00293.28 KZN92321.1 - 8e-06 25.9 0.2 1.7e-05 24.9 0.2 1.5 1 1 0 1 1 1 1 NUDIX domain APH PF01636.23 KZN92323.1 - 2.3e-16 60.4 0.0 8.6e-16 58.6 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN92323.1 - 1.4e-06 28.1 0.0 2.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KZN92323.1 - 0.01 15.3 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KZN92323.1 - 0.034 13.7 0.0 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 RIO1 family HMG_box PF00505.19 KZN92324.1 - 1.3e-12 47.9 0.0 2.9e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KZN92324.1 - 0.023 15.3 0.2 0.081 13.5 0.0 2.0 2 0 0 2 2 2 0 HMG-box domain CENP-F_leu_zip PF10473.9 KZN92327.1 - 0.012 15.6 2.9 0.012 15.6 2.9 1.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 KZN92327.1 - 0.079 13.5 9.4 0.1 13.1 8.2 1.8 1 1 1 2 2 2 0 Apg6 coiled-coil region YabA PF06156.13 KZN92327.1 - 0.26 11.9 5.1 0.5 11.0 5.1 1.5 1 1 0 1 1 1 0 Initiation control protein YabA TMPIT PF07851.13 KZN92327.1 - 0.3 10.3 2.0 0.36 10.0 2.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF3450 PF11932.8 KZN92327.1 - 0.39 10.0 8.9 0.66 9.2 8.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ADIP PF11559.8 KZN92327.1 - 1.2 9.2 11.8 0.13 12.4 6.3 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding GA PF01468.17 KZN92327.1 - 2.6 8.4 11.1 0.39 11.0 5.1 2.6 2 1 0 2 2 2 0 GA module ABC_tran_CTD PF16326.5 KZN92327.1 - 5.7 7.3 10.6 2.3 8.5 6.2 2.2 1 1 0 2 2 2 0 ABC transporter C-terminal domain RINGv PF12906.7 KZN92329.1 - 0.0012 19.0 4.3 0.0012 19.0 4.3 2.1 2 0 0 2 2 2 1 RING-variant domain PHD PF00628.29 KZN92329.1 - 0.0015 18.4 2.5 0.004 17.0 2.5 1.8 1 0 0 1 1 1 1 PHD-finger zf-rbx1 PF12678.7 KZN92329.1 - 0.016 15.4 5.2 0.016 15.4 5.2 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KZN92329.1 - 0.035 14.4 5.7 0.035 14.4 5.7 2.1 2 0 0 2 2 2 0 Ring finger domain zf-ANAPC11 PF12861.7 KZN92329.1 - 0.093 12.8 9.7 0.31 11.1 4.1 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Pkinase PF00069.25 KZN92330.1 - 0.0004 19.8 0.0 0.00054 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN92330.1 - 0.091 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Ank_2 PF12796.7 KZN92331.1 - 4.3e-29 100.9 0.5 3e-10 40.6 0.0 3.0 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN92331.1 - 1.3e-17 63.9 0.7 0.0003 21.3 0.2 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN92331.1 - 1.9e-17 61.5 0.1 0.0014 19.0 0.0 4.7 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 KZN92331.1 - 6.1e-17 61.2 0.2 0.00013 22.3 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KZN92331.1 - 1e-12 48.0 2.2 5.1e-05 23.5 0.1 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Jnk-SapK_ap_N PF09744.9 KZN92332.1 - 0.0011 19.2 3.8 0.0016 18.7 3.8 1.2 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 GIT_CC PF16559.5 KZN92332.1 - 0.002 18.0 0.6 0.0049 16.7 0.6 1.7 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor DMPK_coil PF08826.10 KZN92332.1 - 0.0022 18.1 2.2 0.12 12.5 0.2 3.3 2 1 1 3 3 3 1 DMPK coiled coil domain like DivIC PF04977.15 KZN92332.1 - 0.0057 16.4 0.2 0.011 15.4 0.2 1.6 1 0 0 1 1 1 1 Septum formation initiator Rootletin PF15035.6 KZN92332.1 - 0.0078 16.3 2.3 0.011 15.8 2.3 1.1 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion ADIP PF11559.8 KZN92332.1 - 0.014 15.5 1.6 0.023 14.8 1.6 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 KZN92332.1 - 0.041 14.1 2.2 0.063 13.5 2.2 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) YabA PF06156.13 KZN92332.1 - 0.08 13.6 0.3 0.13 12.9 0.3 1.4 1 0 0 1 1 1 0 Initiation control protein YabA Spc7 PF08317.11 KZN92332.1 - 0.1 11.5 1.9 0.16 10.8 1.5 1.4 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4200 PF13863.6 KZN92332.1 - 0.37 11.2 2.0 0.7 10.3 2.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) ZapB PF06005.12 KZN92334.1 - 0.036 14.5 0.9 0.067 13.7 0.4 1.6 2 0 0 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 KZN92334.1 - 0.066 13.0 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Septum formation initiator UPF0242 PF06785.11 KZN92334.1 - 0.084 13.0 0.2 0.1 12.7 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus MRPL52 PF18699.1 KZN92335.1 - 0.15 12.2 0.1 0.15 12.2 0.1 2.0 1 1 1 2 2 2 0 Mitoribosomal protein mL52 AIG1 PF04548.16 KZN92335.1 - 0.21 10.9 1.5 0.26 10.6 1.5 1.2 1 0 0 1 1 1 0 AIG1 family ZapB PF06005.12 KZN92335.1 - 1.3 9.5 8.5 1.2 9.6 6.3 2.0 2 1 0 2 2 2 0 Cell division protein ZapB NYD-SP28_assoc PF14775.6 KZN92335.1 - 2.2 8.4 6.4 15 5.7 2.4 3.0 1 1 1 2 2 2 0 Sperm tail C-terminal domain Ferric_reduct PF01794.19 KZN92336.1 - 0.3 11.2 11.9 1.4 9.0 11.9 2.2 1 1 0 1 1 1 0 Ferric reductase like transmembrane component DUF1772 PF08592.11 KZN92336.1 - 8.2 6.8 11.9 3.1 8.1 2.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) F-box-like PF12937.7 KZN92337.1 - 0.00026 20.8 4.5 0.00034 20.5 2.4 2.4 2 0 0 2 2 2 1 F-box-like HlyIII PF03006.20 KZN92338.1 - 2.5e-06 27.4 12.8 2.5e-06 27.4 12.8 1.3 1 1 0 1 1 1 1 Haemolysin-III related DUF2721 PF11026.8 KZN92338.1 - 0.16 11.8 0.3 0.16 11.8 0.3 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) Glyco_hydro_18 PF00704.28 KZN92341.1 - 3.1e-78 263.6 1.3 3.7e-78 263.4 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 VCX_VCY PF15231.6 KZN92342.1 - 6.8 7.4 12.3 1.3e+04 -3.2 12.3 3.3 1 1 0 1 1 1 0 Variable charge X/Y family QueF_N PF14819.6 KZN92345.1 - 0.017 15.4 0.0 0.038 14.3 0.0 1.5 1 0 0 1 1 1 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term DUF676 PF05057.14 KZN92346.1 - 0.0017 17.9 0.1 0.02 14.4 0.1 2.1 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Dicty_REP PF05086.12 KZN92346.1 - 0.03 12.3 1.9 0.042 11.8 1.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Abhydrolase_6 PF12697.7 KZN92346.1 - 0.045 14.4 0.0 0.088 13.4 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KZN92346.1 - 0.097 11.9 0.0 0.21 10.8 0.0 1.6 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Anillin_N PF16018.5 KZN92346.1 - 0.13 12.9 0.8 0.33 11.6 0.8 1.7 1 0 0 1 1 1 0 Anillin N-terminus DDE_1 PF03184.19 KZN92348.1 - 1.9e-25 89.6 0.0 2.8e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease TPR_12 PF13424.6 KZN92350.1 - 0 1061.6 105.1 1.8e-22 79.4 0.8 16.9 1 1 19 21 21 21 21 Tetratricopeptide repeat TPR_10 PF13374.6 KZN92350.1 - 1.6e-294 943.4 47.0 6.6e-15 54.4 0.2 22.7 22 0 0 22 22 22 22 Tetratricopeptide repeat TPR_7 PF13176.6 KZN92350.1 - 2.4e-109 349.6 52.7 4.5e-05 23.2 0.1 23.8 23 0 0 23 23 23 22 Tetratricopeptide repeat TPR_1 PF00515.28 KZN92350.1 - 9.2e-99 319.6 39.6 3.3e-05 23.5 0.0 22.4 22 0 0 22 22 22 21 Tetratricopeptide repeat TPR_8 PF13181.6 KZN92350.1 - 4.3e-57 185.6 28.4 0.11 12.8 0.0 22.2 22 0 0 22 22 22 14 Tetratricopeptide repeat TPR_16 PF13432.6 KZN92350.1 - 7.1e-57 189.8 14.7 0.001 19.7 0.8 20.5 11 6 10 21 21 21 16 Tetratricopeptide repeat TPR_17 PF13431.6 KZN92350.1 - 7.9e-50 163.7 0.5 1.2 9.7 0.0 20.9 21 0 0 21 21 21 11 Tetratricopeptide repeat TPR_2 PF07719.17 KZN92350.1 - 1.3e-48 159.3 37.8 0.37 11.0 0.0 22.1 22 0 0 22 22 22 15 Tetratricopeptide repeat TPR_14 PF13428.6 KZN92350.1 - 5e-48 157.7 48.0 0.15 12.9 0.2 23.6 24 0 0 24 24 23 12 Tetratricopeptide repeat TPR_4 PF07721.14 KZN92350.1 - 9.5e-42 137.3 0.0 3.9 8.4 0.0 22.3 22 0 0 22 22 22 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KZN92350.1 - 1.3e-41 143.1 12.6 3.4e-08 33.2 0.5 6.8 1 1 5 7 7 7 6 MalT-like TPR region TPR_19 PF14559.6 KZN92350.1 - 2.6e-38 130.4 21.4 0.0026 18.2 0.2 15.8 4 3 15 20 20 20 15 Tetratricopeptide repeat PPR PF01535.20 KZN92350.1 - 2.8e-25 86.8 15.1 7.8 7.0 0.0 20.3 21 0 0 21 21 21 0 PPR repeat ANAPC3 PF12895.7 KZN92350.1 - 5.3e-22 77.8 0.4 1.5 9.1 0.0 14.2 1 1 15 17 17 17 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 KZN92350.1 - 2.1e-13 50.4 38.4 0.13 12.0 0.1 15.7 1 1 13 17 17 17 3 Tetratricopeptide repeat-like domain DUF1925 PF09094.11 KZN92350.1 - 4.5e-13 49.3 29.1 45 4.5 0.0 18.0 9 6 10 19 19 19 0 Domain of unknown function (DUF1925) nec1 PF10379.9 KZN92350.1 - 9.9e-11 41.5 9.3 26 4.2 0.0 14.0 1 1 18 20 20 20 0 Virulence protein nec1 TPR_3 PF07720.12 KZN92350.1 - 4.1e-09 36.2 18.5 56 3.9 0.0 17.7 21 0 0 21 21 21 0 Tetratricopeptide repeat TPR_11 PF13414.6 KZN92350.1 - 7.9e-08 31.9 55.3 18 5.1 0.0 19.4 21 0 0 21 21 21 0 TPR repeat Atu4866 PF11512.8 KZN92350.1 - 7.9e-05 22.9 37.3 42 4.6 0.0 17.9 22 0 0 22 22 21 0 Agrobacterium tumefaciens protein Atu4866 PTP2 PF17022.5 KZN92350.1 - 9.8e-05 22.1 3.0 82 2.7 0.0 8.2 6 2 3 10 10 9 0 Polar tube protein 2 from Microsporidia DUF676 PF05057.14 KZN92350.1 - 0.00047 19.7 0.1 0.0013 18.3 0.1 1.6 1 1 1 2 2 2 1 Putative serine esterase (DUF676) Sfi1 PF08457.10 KZN92350.1 - 0.0081 14.7 0.8 0.14 10.7 0.2 2.5 2 0 0 2 2 2 1 Sfi1 spindle body protein AAA_16 PF13191.6 KZN92350.1 - 0.021 15.2 0.2 0.087 13.2 0.2 2.2 1 1 0 1 1 1 0 AAA ATPase domain Abhydrolase_6 PF12697.7 KZN92350.1 - 0.042 14.4 0.3 0.13 12.8 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF5557 PF17712.1 KZN92350.1 - 0.057 13.4 0.0 38 4.3 0.0 4.3 3 0 0 3 3 3 0 Family of unknown function (DUF5557) Hydrolase_4 PF12146.8 KZN92350.1 - 0.06 12.6 0.0 0.18 11.0 0.0 1.8 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 KZN92350.1 - 0.17 11.5 0.0 0.39 10.4 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Helo_like_N PF17111.5 KZN92351.1 - 6e-85 283.9 5.2 3e-79 265.2 0.2 2.2 2 0 0 2 2 2 2 Fungal N-terminal domain of STAND proteins NPV_P10 PF05531.12 KZN92351.1 - 0.081 13.4 0.0 0.5 10.9 0.0 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Ribonucleas_3_3 PF14622.6 KZN92352.1 - 1.2e-13 51.3 0.0 1.5e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KZN92352.1 - 3.7e-13 50.0 0.0 1.4e-12 48.2 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain DUF3723 PF12520.8 KZN92353.1 - 1.5e-67 228.5 0.0 3.3e-63 214.1 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3723) IF2_N PF04760.15 KZN92354.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region HlyIII PF03006.20 KZN92355.1 - 3.5e-07 30.2 11.8 3.5e-07 30.2 11.8 1.3 1 1 0 1 1 1 1 Haemolysin-III related DUF2721 PF11026.8 KZN92355.1 - 0.16 11.8 0.3 0.16 11.8 0.3 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) F-box-like PF12937.7 KZN92356.1 - 0.00027 20.8 4.5 0.00034 20.5 2.4 2.4 2 0 0 2 2 2 1 F-box-like 7TMR-DISM_7TM PF07695.11 KZN92357.1 - 0.075 12.9 5.6 0.14 12.0 5.6 1.5 1 0 0 1 1 1 0 7TM diverse intracellular signalling Ferric_reduct PF01794.19 KZN92357.1 - 0.2 11.8 14.7 0.83 9.8 13.6 2.6 2 1 0 2 2 2 0 Ferric reductase like transmembrane component DUF2070 PF09843.9 KZN92357.1 - 0.46 8.7 4.5 0.65 8.2 4.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Cep57_CLD_2 PF14197.6 KZN92358.1 - 0.067 13.3 7.7 0.59 10.3 6.8 2.1 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 ZapB PF06005.12 KZN92358.1 - 0.15 12.5 10.6 0.41 11.1 7.4 2.2 1 1 1 2 2 2 0 Cell division protein ZapB YlqD PF11068.8 KZN92358.1 - 0.26 11.6 3.7 4.9 7.5 0.0 2.1 1 1 1 2 2 2 0 YlqD protein DivIC PF04977.15 KZN92358.1 - 0.58 10.0 5.7 3.8 7.3 4.4 2.3 1 1 1 2 2 2 0 Septum formation initiator DEP PF00610.21 KZN92359.1 - 0.0053 16.8 0.0 0.014 15.5 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF2064 PF09837.9 KZN92359.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) ZapB PF06005.12 KZN92360.1 - 0.036 14.5 0.9 0.067 13.7 0.4 1.6 2 0 0 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 KZN92360.1 - 0.066 13.0 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Septum formation initiator UPF0242 PF06785.11 KZN92360.1 - 0.084 13.0 0.2 0.1 12.7 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Jnk-SapK_ap_N PF09744.9 KZN92362.1 - 0.0011 19.2 3.8 0.0016 18.7 3.8 1.2 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 GIT_CC PF16559.5 KZN92362.1 - 0.002 18.0 0.6 0.0049 16.7 0.6 1.7 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor DMPK_coil PF08826.10 KZN92362.1 - 0.0022 18.1 2.2 0.12 12.5 0.2 3.3 2 1 1 3 3 3 1 DMPK coiled coil domain like DivIC PF04977.15 KZN92362.1 - 0.0057 16.4 0.2 0.011 15.4 0.2 1.6 1 0 0 1 1 1 1 Septum formation initiator Rootletin PF15035.6 KZN92362.1 - 0.0078 16.3 2.3 0.011 15.8 2.3 1.1 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion ADIP PF11559.8 KZN92362.1 - 0.014 15.5 1.6 0.023 14.8 1.6 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 KZN92362.1 - 0.041 14.1 2.2 0.063 13.5 2.2 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) YabA PF06156.13 KZN92362.1 - 0.08 13.6 0.3 0.13 12.9 0.3 1.4 1 0 0 1 1 1 0 Initiation control protein YabA Spc7 PF08317.11 KZN92362.1 - 0.1 11.5 1.9 0.16 10.8 1.5 1.4 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4200 PF13863.6 KZN92362.1 - 0.37 11.2 2.0 0.7 10.3 2.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Ank_2 PF12796.7 KZN92363.1 - 4.3e-29 100.9 0.5 3e-10 40.6 0.0 3.0 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN92363.1 - 1.3e-17 63.9 0.7 0.0003 21.3 0.2 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN92363.1 - 1.9e-17 61.5 0.1 0.0014 19.0 0.0 4.7 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 KZN92363.1 - 6.1e-17 61.2 0.2 0.00013 22.3 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KZN92363.1 - 1e-12 48.0 2.2 5.1e-05 23.5 0.1 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Pkinase PF00069.25 KZN92364.1 - 0.0004 19.8 0.0 0.00054 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN92364.1 - 0.091 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase RINGv PF12906.7 KZN92365.1 - 0.0012 19.0 4.3 0.0012 19.0 4.3 2.1 2 0 0 2 2 2 1 RING-variant domain PHD PF00628.29 KZN92365.1 - 0.0015 18.4 2.5 0.004 17.0 2.5 1.8 1 0 0 1 1 1 1 PHD-finger zf-rbx1 PF12678.7 KZN92365.1 - 0.016 15.4 5.2 0.016 15.4 5.2 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KZN92365.1 - 0.035 14.4 5.7 0.035 14.4 5.7 2.1 2 0 0 2 2 2 0 Ring finger domain zf-ANAPC11 PF12861.7 KZN92365.1 - 0.093 12.8 9.7 0.31 11.1 4.1 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF3450 PF11932.8 KZN92367.1 - 0.0028 17.0 3.1 0.0043 16.4 3.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 KZN92367.1 - 0.0084 16.1 0.6 0.0084 16.1 0.6 1.4 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 KZN92367.1 - 0.023 15.2 6.6 0.023 15.2 6.6 1.7 1 1 1 2 2 2 0 Apg6 coiled-coil region ADIP PF11559.8 KZN92367.1 - 0.029 14.5 4.9 0.029 14.5 4.9 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Bac_GDH PF05088.12 KZN92367.1 - 0.06 10.8 0.9 0.078 10.5 0.9 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase Seryl_tRNA_N PF02403.22 KZN92367.1 - 1.3 9.3 7.6 0.34 11.2 4.6 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Jnk-SapK_ap_N PF09744.9 KZN92367.1 - 8.5 6.6 9.8 0.95 9.7 4.2 1.9 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Helitron_like_N PF14214.6 KZN92368.1 - 2.7e-27 96.2 0.0 6.1e-27 95.1 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 KZN92368.1 - 6.7e-21 74.9 0.2 6.8e-20 71.6 0.0 2.1 2 0 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.6 KZN92368.1 - 3.5e-13 49.7 0.0 7.8e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KZN92368.1 - 1.4e-09 38.5 0.0 3.4e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KZN92368.1 - 0.054 13.5 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) zf_C2HC_14 PF18574.1 KZN92368.1 - 1.4 8.8 4.1 23 4.9 1.0 2.7 2 0 0 2 2 2 0 C2HC Zing finger domain FMN_red PF03358.15 KZN92369.1 - 7.3e-24 84.3 0.0 1.1e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase PGA2 PF07543.12 KZN92369.1 - 0.044 13.8 0.1 0.08 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 Flavodoxin_2 PF02525.17 KZN92369.1 - 0.17 11.6 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin-like fold Cyclin PF08613.11 KZN92370.1 - 2.2e-30 106.2 0.1 3.6e-30 105.5 0.1 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KZN92370.1 - 0.0013 18.4 0.2 0.002 17.9 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain SBF PF01758.16 KZN92371.1 - 4.7e-52 176.5 10.7 4.7e-52 176.5 10.7 2.3 2 1 0 2 2 2 1 Sodium Bile acid symporter family DUF1673 PF07895.11 KZN92371.1 - 6.5 6.4 11.3 1 9.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) LMWPc PF01451.21 KZN92372.1 - 8.8e-22 78.0 0.0 1.6e-21 77.1 0.0 1.4 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase ORC6 PF05460.13 KZN92373.1 - 2.2 7.4 8.1 3.3 6.9 8.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) TPR_12 PF13424.6 KZN92374.1 - 1.4e-128 419.4 48.6 2.6e-19 69.3 0.7 8.0 1 1 8 9 9 9 9 Tetratricopeptide repeat TPR_10 PF13374.6 KZN92374.1 - 1.6e-101 329.8 24.2 7.5e-12 44.7 0.1 9.7 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_7 PF13176.6 KZN92374.1 - 7e-35 116.5 22.8 0.0029 17.5 0.1 10.8 10 0 0 10 10 9 9 Tetratricopeptide repeat TPR_1 PF00515.28 KZN92374.1 - 2.4e-34 115.8 4.8 0.001 18.8 0.0 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_8 PF13181.6 KZN92374.1 - 3.5e-23 79.8 0.6 0.4 11.0 0.0 8.9 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 KZN92374.1 - 1.7e-18 67.0 14.7 0.0017 18.9 0.0 8.8 3 2 6 9 9 9 7 Tetratricopeptide repeat TPR_14 PF13428.6 KZN92374.1 - 3.3e-17 61.7 19.2 0.12 13.2 0.0 10.9 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_MalT PF17874.1 KZN92374.1 - 4.7e-15 55.8 8.3 1.7e-06 27.7 3.6 3.5 1 1 1 3 3 3 3 MalT-like TPR region TPR_4 PF07721.14 KZN92374.1 - 1e-10 41.2 0.0 43 5.1 0.0 9.4 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_2 PF07719.17 KZN92374.1 - 1.5e-10 40.3 15.4 1.6 9.0 0.0 8.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 KZN92374.1 - 1.7e-10 41.3 9.4 0.21 12.1 0.6 6.7 3 2 5 8 8 7 7 Tetratricopeptide repeat TPR_17 PF13431.6 KZN92374.1 - 4.6e-09 36.0 0.0 4.8 7.8 0.0 6.7 7 0 0 7 7 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KZN92374.1 - 4.5e-07 30.0 0.2 4 7.7 0.0 5.2 2 1 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF676 PF05057.14 KZN92374.1 - 5.5e-05 22.8 0.1 0.00014 21.5 0.1 1.6 1 1 1 2 2 2 1 Putative serine esterase (DUF676) PPR PF01535.20 KZN92374.1 - 0.00043 20.3 4.3 54 4.4 0.0 7.3 8 0 0 8 8 8 0 PPR repeat NB-ARC PF00931.22 KZN92374.1 - 0.0013 18.0 0.0 0.0026 17.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_21 PF09976.9 KZN92374.1 - 0.0029 17.3 9.7 21 4.8 0.0 6.4 2 1 5 7 7 6 0 Tetratricopeptide repeat-like domain Abhydrolase_6 PF12697.7 KZN92374.1 - 0.0064 17.1 0.2 0.023 15.3 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF5557 PF17712.1 KZN92374.1 - 0.0095 15.8 0.1 6.5 6.8 0.0 2.6 2 0 0 2 2 2 1 Family of unknown function (DUF5557) AAA_16 PF13191.6 KZN92374.1 - 0.0098 16.3 1.2 0.052 13.9 0.4 2.7 2 1 0 2 2 2 1 AAA ATPase domain NRBF2_MIT PF17169.4 KZN92374.1 - 0.013 15.7 10.1 83 3.5 0.1 7.2 7 2 2 9 9 7 0 MIT domain of nuclear receptor-binding factor 2 TPR_11 PF13414.6 KZN92374.1 - 0.014 15.1 14.3 16 5.3 0.1 7.6 8 0 0 8 8 8 0 TPR repeat Hydrolase_4 PF12146.8 KZN92374.1 - 0.014 14.7 0.0 0.045 13.0 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 KZN92374.1 - 0.017 14.8 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein LAMTOR5 PF16672.5 KZN92374.1 - 0.19 11.6 0.0 47 4.0 0.0 3.8 3 1 1 4 4 3 0 Ragulator complex protein LAMTOR5 ISG65-75 PF11727.8 KZN92374.1 - 0.22 10.7 3.1 40 3.3 0.0 4.1 1 1 4 5 5 5 0 Invariant surface glycoprotein COA2 PF17051.5 KZN92375.1 - 0.19 11.8 0.0 0.46 10.6 0.0 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase assembly factor 2 DDE_1 PF03184.19 KZN92376.1 - 1.5e-29 102.9 0.0 2.5e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease gag_pre-integrs PF13976.6 KZN92377.1 - 8.8e-06 25.5 0.0 2.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain TPR_12 PF13424.6 KZN92378.1 - 7e-151 490.9 62.4 6.2e-23 80.9 1.6 8.9 1 1 6 10 10 10 9 Tetratricopeptide repeat TPR_10 PF13374.6 KZN92378.1 - 2.5e-145 469.1 33.2 2.2e-14 52.8 0.1 12.3 12 0 0 12 12 12 11 Tetratricopeptide repeat TPR_1 PF00515.28 KZN92378.1 - 1.5e-59 195.5 38.8 1.7e-06 27.6 0.2 11.5 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_7 PF13176.6 KZN92378.1 - 1.2e-49 162.7 33.4 0.00016 21.5 0.1 12.5 12 0 0 12 12 11 10 Tetratricopeptide repeat TPR_8 PF13181.6 KZN92378.1 - 2.3e-47 155.3 21.6 6e-05 22.9 0.1 11.1 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.17 KZN92378.1 - 2.1e-38 127.3 37.9 7.9e-05 22.5 0.2 10.9 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_16 PF13432.6 KZN92378.1 - 2.9e-36 123.8 28.8 2.6e-08 34.4 1.8 9.7 4 3 5 9 9 9 8 Tetratricopeptide repeat TPR_14 PF13428.6 KZN92378.1 - 2.8e-29 99.3 33.9 0.012 16.3 0.1 12.5 12 0 0 12 12 11 7 Tetratricopeptide repeat TPR_4 PF07721.14 KZN92378.1 - 3.1e-29 98.5 0.0 0.11 13.2 0.0 11.7 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_17 PF13431.6 KZN92378.1 - 2.6e-25 86.9 0.7 0.81 10.2 0.0 11.1 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KZN92378.1 - 3.9e-23 82.4 35.0 3.4e-10 39.8 5.4 3.9 1 1 3 4 4 4 4 MalT-like TPR region TPR_19 PF14559.6 KZN92378.1 - 7.8e-21 74.4 30.6 5.4e-05 23.6 2.5 7.4 3 2 8 11 11 10 9 Tetratricopeptide repeat ANAPC3 PF12895.7 KZN92378.1 - 7.5e-17 61.3 5.6 0.0037 17.5 1.3 7.3 1 1 7 8 8 8 6 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 KZN92378.1 - 1.5e-15 56.3 8.3 4.4 7.8 0.0 10.3 10 0 0 10 10 10 1 PPR repeat TPR_11 PF13414.6 KZN92378.1 - 8.5e-15 54.2 38.1 0.016 14.9 0.3 10.5 10 0 0 10 10 10 5 TPR repeat DUF1925 PF09094.11 KZN92378.1 - 7.1e-10 39.1 10.9 13 6.2 0.0 9.8 8 1 2 10 10 10 0 Domain of unknown function (DUF1925) MIT PF04212.18 KZN92378.1 - 4.9e-09 36.1 11.2 9.5 6.4 0.0 9.3 10 0 0 10 10 9 0 MIT (microtubule interacting and transport) domain NACHT PF05729.12 KZN92378.1 - 1.5e-05 24.9 0.0 3.5e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_21 PF09976.9 KZN92378.1 - 0.00018 21.3 36.5 3.5 7.3 0.1 9.7 3 3 4 9 9 9 1 Tetratricopeptide repeat-like domain DUF4145 PF13643.6 KZN92378.1 - 0.00032 20.8 9.9 12 6.1 0.0 7.6 3 2 6 9 9 7 0 Domain of unknown function (DUF4145) DUF676 PF05057.14 KZN92378.1 - 0.00079 19.0 0.1 0.0043 16.6 0.1 2.0 1 1 0 1 1 1 1 Putative serine esterase (DUF676) TPR_5 PF12688.7 KZN92378.1 - 0.003 17.8 16.6 0.2 11.9 0.1 5.3 3 1 1 5 5 5 1 Tetratrico peptide repeat NB-ARC PF00931.22 KZN92378.1 - 0.0062 15.8 0.0 0.012 14.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain DUF3856 PF12968.7 KZN92378.1 - 0.0091 16.1 20.6 24 5.0 1.2 7.4 3 3 3 7 7 7 0 Domain of Unknown Function (DUF3856) AAA_16 PF13191.6 KZN92378.1 - 0.019 15.4 0.2 0.11 12.9 0.2 2.4 1 1 0 1 1 1 0 AAA ATPase domain Sec16_C PF12931.7 KZN92378.1 - 0.019 14.6 0.1 1.6e+02 1.7 0.0 5.0 1 1 6 7 7 7 0 Sec23-binding domain of Sec16 SHNi-TPR PF10516.9 KZN92378.1 - 0.021 14.3 10.2 28 4.2 0.1 7.0 9 0 0 9 9 7 0 SHNi-TPR TPR_6 PF13174.6 KZN92378.1 - 0.033 14.8 38.8 1.4 9.7 0.2 9.7 10 0 0 10 10 7 0 Tetratricopeptide repeat DUF3390 PF11870.8 KZN92378.1 - 0.035 14.5 0.0 0.49 10.8 0.0 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF3390) SPO22 PF08631.10 KZN92378.1 - 0.044 13.3 9.3 41 3.5 0.0 6.3 4 2 1 7 7 7 0 Meiosis protein SPO22/ZIP4 like Mad3_BUB1_I PF08311.12 KZN92378.1 - 0.048 13.6 8.8 7.4 6.6 0.1 6.3 6 0 0 6 6 6 0 Mad3/BUB1 homology region 1 Hydrolase_4 PF12146.8 KZN92378.1 - 0.085 12.1 0.0 0.22 10.8 0.0 1.7 1 0 0 1 1 1 0 Serine aminopeptidase, S33 nec1 PF10379.9 KZN92378.1 - 0.089 12.3 0.0 1.1e+02 2.2 0.0 4.3 3 2 1 4 4 4 0 Virulence protein nec1 Abhydrolase_6 PF12697.7 KZN92378.1 - 0.1 13.2 0.0 0.26 11.8 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KZN92378.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein TPR_3 PF07720.12 KZN92378.1 - 0.2 11.7 19.0 4.9 7.3 0.0 8.1 9 0 0 9 9 9 0 Tetratricopeptide repeat 14-3-3 PF00244.20 KZN92378.1 - 0.25 10.8 2.1 24 4.4 0.1 4.3 3 2 1 4 4 4 0 14-3-3 protein FixS PF03597.15 KZN92378.1 - 2.6 7.8 7.3 53 3.6 0.0 4.9 6 0 0 6 6 5 0 Cytochrome oxidase maturation protein cbb3-type DDE_1 PF03184.19 KZN92380.1 - 1.2e-28 100.0 0.0 1.8e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KZN92380.1 - 9.1e-08 32.0 0.0 2.6e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF676 PF05057.14 KZN92381.1 - 3.8e-05 23.3 0.1 0.00011 21.8 0.1 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KZN92381.1 - 0.014 16.0 0.0 0.028 15.0 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KZN92381.1 - 0.043 13.5 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 KZN92381.1 - 0.059 12.6 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Anillin_N PF16018.5 KZN92381.1 - 0.061 13.9 0.6 0.19 12.3 0.3 2.0 2 0 0 2 2 2 0 Anillin N-terminus DUF4618 PF15397.6 KZN92382.1 - 0.0072 15.8 0.1 0.01 15.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) LPP PF04728.13 KZN92382.1 - 0.034 14.5 0.6 0.064 13.6 0.1 1.8 2 0 0 2 2 2 0 Lipoprotein leucine-zipper TolA_bind_tri PF16331.5 KZN92382.1 - 0.036 14.2 0.5 0.1 12.7 0.0 2.1 2 1 0 2 2 2 0 TolA binding protein trimerisation CCDC24 PF15669.5 KZN92383.1 - 0.00033 20.6 1.6 0.00037 20.4 1.6 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 24 family CLZ PF16526.5 KZN92383.1 - 0.0007 19.9 7.8 0.00086 19.6 2.3 2.3 1 1 0 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels LRRFIP PF09738.9 KZN92383.1 - 0.0014 18.2 2.5 0.0019 17.8 2.5 1.1 1 0 0 1 1 1 1 LRRFIP family GAS PF13851.6 KZN92383.1 - 0.0052 16.1 8.0 0.0072 15.7 8.0 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF4618 PF15397.6 KZN92383.1 - 0.0053 16.2 5.0 0.012 15.1 5.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4618) Peripla_BP_2 PF01497.18 KZN92383.1 - 0.0086 15.7 0.9 0.011 15.3 0.9 1.2 1 0 0 1 1 1 1 Periplasmic binding protein TolA_bind_tri PF16331.5 KZN92383.1 - 0.0091 16.1 0.4 0.0091 16.1 0.4 1.8 1 1 0 1 1 1 1 TolA binding protein trimerisation MAD PF05557.13 KZN92383.1 - 0.016 13.6 8.4 0.051 12.0 8.5 1.6 1 1 1 2 2 2 0 Mitotic checkpoint protein Spectrin PF00435.21 KZN92383.1 - 0.02 15.4 1.3 0.02 15.4 1.3 2.2 1 1 1 2 2 2 0 Spectrin repeat Seryl_tRNA_N PF02403.22 KZN92383.1 - 0.021 15.0 5.6 0.039 14.2 5.0 1.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain LUC7 PF03194.15 KZN92383.1 - 0.022 14.5 4.4 0.023 14.3 4.4 1.1 1 0 0 1 1 1 0 LUC7 N_terminus Csm1_N PF18504.1 KZN92383.1 - 0.026 14.9 2.0 0.026 14.9 2.0 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain MctB PF11382.8 KZN92383.1 - 0.058 13.1 2.3 0.076 12.7 2.3 1.2 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB CENP-F_leu_zip PF10473.9 KZN92383.1 - 0.064 13.3 7.3 0.096 12.7 7.3 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Syntaxin-6_N PF09177.11 KZN92383.1 - 0.067 13.8 5.2 0.28 11.8 4.9 1.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FlaC_arch PF05377.11 KZN92383.1 - 0.085 13.3 2.9 0.7 10.3 0.3 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) GRDP-like PF07173.12 KZN92383.1 - 0.099 13.3 0.9 0.15 12.7 0.9 1.4 1 1 0 1 1 1 0 Glycine-rich domain-containing protein-like CorA PF01544.18 KZN92383.1 - 0.11 11.8 1.1 0.13 11.5 1.1 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Utp21 PF04192.12 KZN92383.1 - 0.13 11.7 8.0 0.19 11.2 2.9 2.1 1 1 1 2 2 2 0 Utp21 specific WD40 associated putative domain bZIP_Maf PF03131.17 KZN92383.1 - 0.18 12.3 6.5 1.3 9.6 1.0 2.3 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF2730 PF10805.8 KZN92383.1 - 0.2 11.8 1.8 0.36 11.0 0.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Tropomyosin_1 PF12718.7 KZN92383.1 - 0.2 11.8 10.9 0.61 10.2 10.9 1.7 1 1 0 1 1 1 0 Tropomyosin like GAT PF03127.14 KZN92383.1 - 0.21 11.9 4.1 0.75 10.1 4.1 2.0 1 1 0 1 1 1 0 GAT domain NYD-SP28_assoc PF14775.6 KZN92383.1 - 0.24 11.5 3.8 0.15 12.2 0.8 2.1 1 1 0 2 2 2 0 Sperm tail C-terminal domain DUF4349 PF14257.6 KZN92383.1 - 0.25 10.7 6.0 0.35 10.3 6.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) XhlA PF10779.9 KZN92383.1 - 0.26 11.5 5.2 0.57 10.4 0.6 2.2 2 0 0 2 2 2 0 Haemolysin XhlA DUF4407 PF14362.6 KZN92383.1 - 0.29 10.5 4.5 0.41 10.0 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2205 PF10224.9 KZN92383.1 - 0.32 11.0 5.8 0.099 12.7 1.0 2.2 1 1 1 2 2 2 0 Short coiled-coil protein DivIC PF04977.15 KZN92383.1 - 0.68 9.7 8.9 1 9.2 1.6 2.4 1 1 1 2 2 2 0 Septum formation initiator JIP_LZII PF16471.5 KZN92383.1 - 0.72 10.1 9.0 2.4 8.4 3.7 3.0 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II YabA PF06156.13 KZN92383.1 - 0.74 10.5 7.0 0.9 10.2 2.0 2.3 1 1 2 3 3 3 0 Initiation control protein YabA Ribosomal_S20p PF01649.18 KZN92383.1 - 0.94 10.2 6.2 2.9 8.6 6.2 1.8 1 1 0 1 1 1 0 Ribosomal protein S20 Cnn_1N PF07989.11 KZN92383.1 - 0.96 9.7 8.2 1.1 9.5 2.0 2.1 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 DUF5320 PF17253.2 KZN92383.1 - 1 10.5 5.6 0.73 10.9 0.8 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5320) DivIVA PF05103.13 KZN92383.1 - 1.1 9.3 9.9 0.079 13.0 2.1 2.1 1 1 1 2 2 2 0 DivIVA protein bZIP_2 PF07716.15 KZN92383.1 - 1.7 8.8 12.1 10 6.3 2.5 3.2 2 1 1 3 3 3 0 Basic region leucine zipper Prefoldin PF02996.17 KZN92383.1 - 1.9 8.5 8.0 0.42 10.5 1.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit HALZ PF02183.18 KZN92383.1 - 2.2 8.6 7.1 1.8 8.8 0.7 2.9 2 1 1 3 3 3 0 Homeobox associated leucine zipper EMP24_GP25L PF01105.24 KZN92383.1 - 4.4 7.2 6.5 4.3 7.3 0.9 2.0 1 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF2203 PF09969.9 KZN92383.1 - 5.3 7.8 6.8 17 6.1 0.5 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Spc24 PF08286.11 KZN92383.1 - 5.5 7.3 9.7 1 9.6 3.3 2.1 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 TMPIT PF07851.13 KZN92383.1 - 6.5 5.9 6.0 11 5.2 5.1 1.4 1 1 0 1 1 1 0 TMPIT-like protein EST1_DNA_bind PF10373.9 KZN92385.1 - 0.0026 17.3 0.0 0.0052 16.3 0.0 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain DUF3435 PF11917.8 KZN92390.1 - 4.8e-108 361.8 0.6 6.4e-108 361.4 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) FOXP-CC PF16159.5 KZN92390.1 - 0.0059 17.2 1.0 0.031 14.9 0.1 2.6 2 0 0 2 2 2 1 FOXP coiled-coil domain Spc7 PF08317.11 KZN92390.1 - 0.038 12.9 2.1 0.062 12.2 2.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Fez1 PF06818.15 KZN92390.1 - 0.058 13.8 2.4 0.11 12.9 2.4 1.5 1 0 0 1 1 1 0 Fez1 SF3A3 PF16837.5 KZN92390.1 - 0.11 13.0 3.7 0.22 12.1 3.7 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 BRE1 PF08647.11 KZN92390.1 - 0.13 12.3 1.2 0.36 10.9 1.2 1.7 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase TPR_MLP1_2 PF07926.12 KZN92390.1 - 0.22 11.6 2.6 0.41 10.7 2.6 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein CENP-H PF05837.12 KZN92390.1 - 0.25 11.8 2.5 0.55 10.7 2.5 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) zf-PARP PF00645.18 KZN92391.1 - 0.0055 17.5 0.0 0.01 16.6 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region E1-E2_ATPase PF00122.20 KZN92392.1 - 1.6e-45 154.9 0.0 4.3e-45 153.4 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KZN92392.1 - 1.4e-34 120.3 0.0 2.9e-34 119.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KZN92392.1 - 2.8e-31 107.7 2.6 3.3e-10 40.2 0.0 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KZN92392.1 - 0.00057 19.7 0.0 0.0074 16.1 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KZN92392.1 - 0.00096 19.6 0.0 0.0026 18.2 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SNAD4 PF18750.1 KZN92392.1 - 0.073 13.2 0.4 1.3 9.2 0.0 2.9 3 0 0 3 3 3 0 Secreted Novel AID/APOBEC-like Deaminase 4 Caveolin PF01146.17 KZN92392.1 - 2.8 7.9 6.2 0.64 10.0 0.8 2.6 3 0 0 3 3 3 0 Caveolin Zip PF02535.22 KZN92393.1 - 2.3e-59 201.3 5.0 4.2e-59 200.4 5.0 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter Cu-oxidase_2 PF07731.14 KZN92394.1 - 6.1e-43 145.8 4.1 4.1e-35 120.5 0.5 3.7 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KZN92394.1 - 2.9e-40 137.0 6.4 7.7e-40 135.6 0.1 3.5 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 KZN92394.1 - 4.6e-22 78.8 0.0 6.9e-17 62.0 0.0 2.7 2 0 0 2 2 2 2 Multicopper oxidase FAM153 PF15722.5 KZN92394.1 - 0.49 10.8 2.5 0.97 9.8 2.5 1.4 1 0 0 1 1 1 0 FAM153 family Cu-oxidase_3 PF07732.15 KZN92395.1 - 1.2e-10 41.5 0.1 2.1e-10 40.7 0.1 1.3 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KZN92395.1 - 4.8e-05 23.1 0.1 6e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Multicopper oxidase DUF3723 PF12520.8 KZN92396.1 - 8.1e-190 631.8 0.1 1.2e-189 631.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) Ferric_reduct PF01794.19 KZN92399.1 - 5.6e-11 42.6 6.3 5.6e-11 42.6 6.3 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KZN92399.1 - 2.2e-10 40.6 0.0 4.6e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KZN92399.1 - 9.9e-06 25.8 0.0 1.5e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NUDIX PF00293.28 KZN92401.1 - 0.00015 21.8 0.0 0.00053 20.0 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain APH PF01636.23 KZN92405.1 - 4.7e-14 52.9 0.0 1e-13 51.8 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KZN92405.1 - 0.025 13.4 0.0 0.6 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) APH PF01636.23 KZN92407.1 - 2.8e-05 24.2 0.2 0.0036 17.2 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN92407.1 - 0.00029 20.5 0.0 0.0004 20.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KZN92407.1 - 0.00077 18.9 0.2 0.0016 17.8 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KZN92407.1 - 0.0046 16.3 0.0 0.0073 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF2841 PF11001.8 KZN92409.1 - 3e-19 69.3 0.0 5.1e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Glyco_hydro_71 PF03659.14 KZN92410.1 - 2.2e-129 431.5 3.1 2.6e-129 431.3 3.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.6 KZN92410.1 - 0.024 14.6 0.1 0.041 13.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) DUF3450 PF11932.8 KZN92413.1 - 0.0025 17.2 2.9 0.0038 16.6 2.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 KZN92413.1 - 0.0083 16.2 0.6 0.0083 16.2 0.6 1.5 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 KZN92413.1 - 0.022 15.3 6.6 0.022 15.3 6.6 1.7 1 1 1 2 2 2 0 Apg6 coiled-coil region ADIP PF11559.8 KZN92413.1 - 0.028 14.5 4.9 0.028 14.5 4.9 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Bac_GDH PF05088.12 KZN92413.1 - 0.036 11.6 0.7 0.046 11.2 0.7 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase Seryl_tRNA_N PF02403.22 KZN92413.1 - 1.6 9.0 7.8 0.42 10.9 4.5 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain YabA PF06156.13 KZN92413.1 - 5.2 7.8 5.3 9.3 7.0 5.3 1.4 1 1 0 1 1 1 0 Initiation control protein YabA Jnk-SapK_ap_N PF09744.9 KZN92413.1 - 8.1 6.6 9.8 0.95 9.7 4.2 1.9 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 CENP-F_leu_zip PF10473.9 KZN92414.1 - 0.00049 20.1 23.0 0.022 14.8 11.8 2.8 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HMMR_N PF15905.5 KZN92414.1 - 0.0024 17.4 20.4 0.0045 16.5 20.4 1.4 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal CorA PF01544.18 KZN92414.1 - 0.02 14.2 8.8 0.025 13.9 7.5 1.8 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein UPF0242 PF06785.11 KZN92414.1 - 0.044 13.9 23.7 0.057 13.5 8.3 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Taxilin PF09728.9 KZN92414.1 - 0.045 12.9 20.6 0.092 11.9 20.6 1.4 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Spc7 PF08317.11 KZN92414.1 - 0.091 11.6 25.0 0.0073 15.2 13.2 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein Csm1_N PF18504.1 KZN92414.1 - 0.15 12.4 17.0 3.5 8.0 0.5 4.5 2 1 2 4 4 4 0 Csm1 N-terminal domain MafB PF06255.13 KZN92414.1 - 0.18 11.2 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Neisseria toxin MafB DUF948 PF06103.11 KZN92414.1 - 0.26 11.6 2.8 0.48 10.7 0.6 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4201 PF13870.6 KZN92414.1 - 0.56 9.9 21.6 0.63 9.8 4.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) IL4 PF00727.18 KZN92414.1 - 0.6 10.4 6.8 0.83 9.9 0.1 3.2 2 1 2 4 4 4 0 Interleukin 4 Syntaxin_2 PF14523.6 KZN92414.1 - 0.78 10.1 12.1 0.65 10.4 8.0 2.8 2 0 0 2 2 2 0 Syntaxin-like protein Bacillus_HBL PF05791.11 KZN92414.1 - 0.8 9.5 12.2 0.4 10.5 5.9 2.5 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DHR10 PF18595.1 KZN92414.1 - 0.85 9.7 26.4 0.88 9.6 6.1 3.4 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain ATG16 PF08614.11 KZN92414.1 - 0.99 9.6 24.3 0.22 11.8 5.8 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HAP1_N PF04849.13 KZN92414.1 - 1 8.5 24.7 0.057 12.6 7.0 2.6 1 1 0 2 2 2 0 HAP1 N-terminal conserved region YkyA PF10368.9 KZN92414.1 - 1.2 8.8 26.7 0.91 9.2 6.8 2.5 2 1 1 3 3 2 0 Putative cell-wall binding lipoprotein APG6_N PF17675.1 KZN92414.1 - 1.2 9.6 26.0 2.6 8.6 13.0 3.0 1 1 1 2 2 2 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 KZN92414.1 - 1.4 9.0 26.8 0.087 12.9 16.7 3.4 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein AAA_15 PF13175.6 KZN92414.1 - 2.9 7.5 16.7 1.7 8.2 0.5 2.1 1 1 0 2 2 2 0 AAA ATPase domain DUF1664 PF07889.12 KZN92414.1 - 3.2 7.8 15.1 1.9 8.5 5.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HemX PF04375.14 KZN92414.1 - 3.4 6.9 25.1 3.4 6.9 8.0 2.3 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase BLOC1_2 PF10046.9 KZN92414.1 - 3.6 8.0 19.2 0.53 10.6 2.0 4.2 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-Q PF13094.6 KZN92414.1 - 3.9 7.6 17.6 0.5 10.6 3.8 2.8 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Lebercilin PF15619.6 KZN92414.1 - 4.6 6.9 26.3 11 5.6 17.6 2.6 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF3450 PF11932.8 KZN92414.1 - 4.7 6.5 23.4 2.3 7.5 7.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Spectrin PF00435.21 KZN92414.1 - 6.5 7.3 17.4 6.6 7.3 4.6 2.7 2 0 0 2 2 2 0 Spectrin repeat DUF502 PF04367.13 KZN92415.1 - 0.088 12.7 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF502) DUF5037 PF16440.5 KZN92415.1 - 0.089 12.3 0.1 0.097 12.2 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5037) 4HBT PF03061.22 KZN92417.1 - 0.0019 18.5 0.0 0.011 16.1 0.0 2.0 1 1 0 1 1 1 1 Thioesterase superfamily Ank_2 PF12796.7 KZN92418.1 - 6.5e-53 177.3 3.8 2e-10 41.1 0.3 5.6 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN92418.1 - 3.4e-45 151.9 10.3 3.3e-10 40.3 0.0 9.1 4 3 5 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN92418.1 - 9.1e-40 130.1 4.1 0.00021 21.5 0.0 11.0 11 0 0 11 11 11 8 Ankyrin repeat Ank_5 PF13857.6 KZN92418.1 - 9.9e-36 121.3 10.4 5.5e-07 29.7 0.0 9.8 4 3 6 10 10 10 9 Ankyrin repeats (many copies) Ank PF00023.30 KZN92418.1 - 1.3e-27 95.0 11.1 0.00034 20.9 0.0 11.5 12 0 0 12 12 12 7 Ankyrin repeat Myb_DNA-binding PF00249.31 KZN92419.1 - 1.7e-05 24.9 0.1 3.8e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KZN92419.1 - 0.00029 21.0 0.1 0.0009 19.5 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KZN92419.1 - 0.051 13.5 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Myb DNA-binding like Pro_dh PF01619.18 KZN92420.1 - 4.3e-64 216.9 0.1 5.2e-64 216.6 0.1 1.1 1 0 0 1 1 1 1 Proline dehydrogenase AP_endonuc_2 PF01261.24 KZN92420.1 - 0.085 12.3 0.0 0.22 10.9 0.0 1.7 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Sugar_tr PF00083.24 KZN92421.1 - 1.8e-99 333.7 17.8 2.1e-99 333.5 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN92421.1 - 5.5e-29 101.2 51.8 1.4e-21 76.8 27.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PsbW PF07123.12 KZN92422.1 - 0.15 12.1 2.3 0.51 10.3 1.7 2.2 1 1 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Aldedh PF00171.22 KZN92423.1 - 1.8e-95 320.2 0.0 2.1e-95 319.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DAO PF01266.24 KZN92424.1 - 1.6e-29 103.6 0.0 1.8e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KZN92424.1 - 5.7e-05 23.3 0.0 0.00012 22.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KZN92424.1 - 0.0016 17.8 0.0 0.0029 16.9 0.0 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KZN92424.1 - 0.01 15.0 0.0 0.27 10.3 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 KZN92424.1 - 0.045 13.0 0.0 0.19 10.9 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 KZN92424.1 - 0.066 13.8 0.0 0.21 12.2 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.18 KZN92425.1 - 1.2e-07 31.1 0.7 6.7e-07 28.6 0.7 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain RabGAP-TBC PF00566.18 KZN92428.1 - 2.1e-32 112.5 0.3 3.3e-32 111.9 0.3 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Wtap PF17098.5 KZN92428.1 - 0.031 14.2 0.2 0.072 13.0 0.2 1.6 1 0 0 1 1 1 0 WTAP/Mum2p family Pkinase PF00069.25 KZN92429.1 - 2.4e-56 191.0 0.0 3.9e-56 190.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN92429.1 - 1.4e-20 73.7 0.0 2.1e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KZN92429.1 - 0.00012 21.5 0.0 0.00045 19.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KZN92429.1 - 0.00019 20.8 0.0 0.00044 19.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KZN92429.1 - 0.00056 19.9 0.1 0.018 15.0 0.1 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KZN92429.1 - 0.0022 17.0 0.0 0.0039 16.2 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KZN92429.1 - 0.011 15.3 0.1 0.031 13.9 0.1 1.7 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KZN92429.1 - 0.03 13.1 0.0 0.055 12.2 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase LRR_6 PF13516.6 KZN92430.1 - 1.6e-11 43.3 5.7 0.21 11.7 0.0 7.1 9 0 0 9 9 9 3 Leucine Rich repeat F-box-like PF12937.7 KZN92430.1 - 1.1e-10 41.2 0.0 4.4e-10 39.3 0.0 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN92430.1 - 5.8e-09 35.6 0.1 5.8e-08 32.4 0.0 2.9 2 1 0 2 2 2 1 F-box domain LRR_4 PF12799.7 KZN92430.1 - 3.6e-06 27.2 8.8 0.0079 16.6 0.1 4.3 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) Nucleo_P87 PF07267.11 KZN92430.1 - 0.0038 16.2 0.0 0.0053 15.7 0.0 1.3 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 PRANC PF09372.10 KZN92430.1 - 0.17 12.3 0.2 0.76 10.1 0.0 2.2 2 0 0 2 2 2 0 PRANC domain LRR_1 PF00560.33 KZN92430.1 - 2.5 9.0 17.9 4.6 8.2 0.1 5.7 6 1 0 6 6 6 0 Leucine Rich Repeat zinc_ribbon_16 PF17034.5 KZN92431.1 - 6.2e-24 84.6 9.6 1.4e-23 83.4 9.6 1.7 1 0 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 KZN92431.1 - 0.066 12.8 12.4 0.025 14.2 8.2 2.5 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 KZN92431.1 - 0.082 13.2 7.1 0.026 14.8 3.1 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger domain Efg1 PF10153.9 KZN92432.1 - 2.6e-34 118.0 8.8 2.6e-34 118.0 8.8 3.2 3 0 0 3 3 3 1 rRNA-processing protein Efg1 Menin PF05053.13 KZN92432.1 - 1.4 7.2 13.7 2.4 6.4 13.7 1.3 1 0 0 1 1 1 0 Menin Membralin PF09746.9 KZN92432.1 - 8.7 5.3 12.6 11 5.0 7.1 2.1 2 0 0 2 2 2 0 Tumour-associated protein PTS_2-RNA PF01885.16 KZN92434.1 - 5.9e-70 235.0 0.0 7.1e-70 234.7 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF1778 PF08681.11 KZN92434.1 - 0.078 12.9 0.3 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1778) Dioxygenase_C PF00775.21 KZN92435.1 - 7.7e-49 165.6 0.0 1e-48 165.2 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KZN92435.1 - 1.2e-26 92.3 0.1 1.9e-26 91.7 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KZN92435.1 - 2e-06 27.9 0.0 7.3e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KZN92435.1 - 0.012 15.6 0.0 0.66 10.0 0.0 2.7 3 0 0 3 3 3 0 CarboxypepD_reg-like domain Lipase_C PF18067.1 KZN92435.1 - 0.012 16.1 0.0 0.026 15.1 0.0 1.5 1 0 0 1 1 1 0 Lipase C-terminal domain SpaA PF17802.1 KZN92435.1 - 0.096 13.0 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Prealbumin-like fold domain DUF4198 PF10670.9 KZN92435.1 - 0.1 13.0 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) Abhydrolase_1 PF00561.20 KZN92436.1 - 2.5e-19 69.9 0.0 5.8e-16 58.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KZN92436.1 - 1.2e-17 64.0 0.1 3.8e-17 62.3 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KZN92436.1 - 3.6e-14 53.9 0.0 5.5e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KZN92436.1 - 7e-06 25.0 0.0 8.7e-06 24.6 0.0 1.3 1 1 0 1 1 1 1 Ndr family Abhydrolase_5 PF12695.7 KZN92436.1 - 0.00019 21.2 0.0 0.00059 19.7 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KZN92436.1 - 0.00019 21.3 0.0 0.008 16.0 0.0 2.4 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KZN92436.1 - 0.00074 19.1 0.0 0.091 12.2 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Ser_hydrolase PF06821.13 KZN92436.1 - 0.0025 17.7 0.3 0.044 13.7 0.3 2.1 1 1 0 1 1 1 1 Serine hydrolase BAAT_C PF08840.11 KZN92436.1 - 0.003 17.5 0.1 0.0068 16.4 0.1 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.13 KZN92436.1 - 0.006 16.3 0.4 0.01 15.6 0.4 1.4 1 0 0 1 1 1 1 PGAP1-like protein DLH PF01738.18 KZN92436.1 - 0.015 14.9 0.1 3.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF915 PF06028.11 KZN92436.1 - 0.047 13.0 0.2 0.15 11.4 0.1 1.8 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 KZN92436.1 - 0.061 13.0 0.0 0.12 12.0 0.0 1.4 1 1 0 1 1 1 0 Putative esterase LIDHydrolase PF10230.9 KZN92436.1 - 0.087 12.4 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF676 PF05057.14 KZN92436.1 - 0.15 11.5 0.1 0.63 9.5 0.1 2.0 2 1 0 2 2 2 0 Putative serine esterase (DUF676) Aldo_ket_red PF00248.21 KZN92437.1 - 8e-36 123.7 0.1 2.3e-33 115.6 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family eRF1_1 PF03463.15 KZN92438.1 - 4.3e-47 159.3 0.0 6.7e-47 158.7 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 KZN92438.1 - 1.9e-20 73.4 0.0 3.4e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 KZN92438.1 - 4.6e-19 69.1 0.0 7.1e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 JHD PF17811.1 KZN92439.1 - 0.0069 16.9 0.4 0.048 14.2 0.1 2.2 2 0 0 2 2 2 1 Jumonji helical domain MFS_1 PF07690.16 KZN92440.1 - 2.1e-22 79.6 48.0 4.9e-20 71.8 31.4 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP-synt_C PF00137.21 KZN92441.1 - 1.5e-35 121.3 29.1 2.1e-21 76.0 11.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF2970 PF11174.8 KZN92441.1 - 0.07 13.0 1.1 0.07 13.0 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) DUF2244 PF10003.9 KZN92441.1 - 1.1 8.9 3.4 0.32 10.6 0.2 1.9 2 1 0 2 2 2 0 Integral membrane protein (DUF2244) Peptidase_C14 PF00656.22 KZN92442.1 - 5.1e-63 213.3 0.0 6.5e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Cpn60_TCP1 PF00118.24 KZN92443.1 - 7.4e-151 503.1 4.9 8.5e-151 502.9 4.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rep_fac_C PF08542.11 KZN92443.1 - 0.0095 16.3 0.1 1.1 9.7 0.1 2.8 2 0 0 2 2 2 1 Replication factor C C-terminal domain FtsA PF14450.6 KZN92443.1 - 0.017 15.5 0.1 0.042 14.3 0.1 1.8 1 0 0 1 1 1 0 Cell division protein FtsA Beta_helix_2 PF18835.1 KZN92443.1 - 0.16 11.8 0.2 3.6 7.4 0.3 2.6 2 0 0 2 2 2 0 Beta helix repeat of Inulin fructotransferase zf-H2C2 PF09337.10 KZN92444.1 - 1.5e-15 57.1 1.8 2.6e-15 56.3 1.8 1.4 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 KZN92444.1 - 1.9e-10 40.7 0.4 3.2e-10 39.9 0.4 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 KZN92444.1 - 5.6e-06 26.6 0.0 9.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KZN92444.1 - 0.01 16.5 0.0 0.028 15.1 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KZN92444.1 - 0.088 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.7 KZN92444.1 - 0.19 11.8 0.0 0.35 11.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LANC_like PF05147.13 KZN92445.1 - 2.4e-21 75.7 0.0 2.4e-18 65.9 0.0 2.4 1 1 1 2 2 2 2 Lanthionine synthetase C-like protein F-box-like PF12937.7 KZN92446.1 - 3.1e-05 23.8 0.3 7.7e-05 22.5 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 KZN92446.1 - 0.0091 15.5 0.6 0.13 11.9 0.2 2.5 2 0 0 2 2 2 1 F-box LRR_4 PF12799.7 KZN92446.1 - 0.016 15.6 0.3 13 6.4 0.0 4.2 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box PF00646.33 KZN92446.1 - 0.025 14.5 1.0 0.072 13.0 0.1 2.3 2 0 0 2 2 2 0 F-box domain Ribosomal_S26e PF01283.19 KZN92447.1 - 7.6e-53 177.5 7.6 9e-53 177.3 7.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 KZN92447.1 - 0.026 14.5 0.5 0.065 13.2 0.0 1.9 2 0 0 2 2 2 0 Zinc binding domain CBS PF00571.28 KZN92448.1 - 6.4e-36 122.6 4.9 5e-09 36.5 0.0 5.3 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 KZN92448.1 - 2.6e-10 40.1 0.0 7.4e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 PB1 domain Importin_rep_4 PF18808.1 KZN92449.1 - 9.8e-34 115.5 6.0 4.3e-33 113.5 1.5 3.6 3 0 0 3 3 3 1 Importin repeat HEAT_EZ PF13513.6 KZN92449.1 - 1.4e-23 82.9 12.2 2.1e-11 44.0 0.5 9.4 7 2 1 8 8 8 3 HEAT-like repeat Importin_rep_5 PF18816.1 KZN92449.1 - 1e-22 80.2 1.7 3.9e-22 78.3 1.7 2.1 1 0 0 1 1 1 1 Importin repeat HEAT_2 PF13646.6 KZN92449.1 - 5.5e-18 65.1 6.5 3.4e-05 24.2 0.0 7.7 6 1 1 7 7 7 4 HEAT repeats HEAT PF02985.22 KZN92449.1 - 1.9e-17 61.8 12.8 0.0014 18.7 0.0 12.2 15 0 0 15 15 13 2 HEAT repeat Importin_rep_6 PF18829.1 KZN92449.1 - 1.3e-13 51.0 0.5 1.3e-13 51.0 0.5 3.0 3 0 0 3 3 2 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 KZN92449.1 - 1.1e-09 38.8 0.1 0.0068 17.0 0.0 5.9 2 2 3 5 5 5 1 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 KZN92449.1 - 5.6e-09 36.1 0.8 0.15 11.9 0.0 6.5 5 4 2 7 7 6 1 Domain of unknown function (DUF3385) MMS19_C PF12460.8 KZN92449.1 - 1.8e-08 33.9 7.7 3.1e-06 26.6 1.0 5.1 5 1 1 6 6 6 2 RNAPII transcription regulator C-terminal Cnd1 PF12717.7 KZN92449.1 - 2.2e-08 34.3 0.0 0.23 11.5 0.0 5.0 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 KZN92449.1 - 7.4e-08 32.4 0.1 0.0084 15.9 0.1 4.7 4 1 1 5 5 5 1 rRNA processing/ribosome biogenesis CLASP_N PF12348.8 KZN92449.1 - 9.2e-08 31.9 0.9 0.16 11.5 0.0 6.4 5 3 2 7 7 7 3 CLASP N terminal Adaptin_N PF01602.20 KZN92449.1 - 4.1e-07 28.9 0.0 0.0015 17.1 0.1 3.0 2 1 1 3 3 3 2 Adaptin N terminal region MMS19_N PF14500.6 KZN92449.1 - 0.00025 20.7 0.6 1.4 8.4 0.2 4.4 5 1 0 5 5 5 2 Dos2-interacting transcription regulator of RNA-Pol-II Arm PF00514.23 KZN92449.1 - 0.00084 19.3 5.3 0.29 11.2 0.1 4.2 5 0 0 5 5 3 2 Armadillo/beta-catenin-like repeat DUF4042 PF13251.6 KZN92449.1 - 0.0057 16.4 1.4 11 5.6 0.0 4.8 6 0 0 6 6 5 0 Domain of unknown function (DUF4042) IBN_N PF03810.19 KZN92449.1 - 0.0068 16.3 0.0 0.064 13.2 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain BP28CT PF08146.12 KZN92449.1 - 0.0086 15.9 0.3 0.3 10.9 0.0 3.4 2 1 0 2 2 2 1 BP28CT (NUC211) domain RTP1_C1 PF10363.9 KZN92449.1 - 0.0097 16.1 0.2 83 3.4 0.0 5.1 6 1 0 7 7 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 KZN92449.1 - 0.01 15.1 0.1 15 4.7 0.0 4.1 3 1 1 4 4 4 0 Nuclear condensing complex subunits, C-term domain DNA_alkylation PF08713.11 KZN92449.1 - 0.036 13.8 0.0 0.14 11.9 0.0 2.1 1 0 0 1 1 1 0 DNA alkylation repair enzyme GP24_25 PF17388.2 KZN92449.1 - 0.089 12.8 0.4 0.57 10.2 0.4 2.5 1 0 0 1 1 1 0 Tail assembly gene products 24 & 25 Rif1_N PF12231.8 KZN92449.1 - 0.15 11.0 0.2 5.9 5.8 0.0 3.1 3 0 0 3 3 3 0 Rap1-interacting factor 1 N terminal Telomere_reg-2 PF10193.9 KZN92449.1 - 0.3 11.5 3.9 2.9 8.4 0.4 3.8 2 2 2 4 4 4 0 Telomere length regulation protein V-ATPase_H_N PF03224.14 KZN92449.1 - 0.39 10.0 2.8 9.3 5.4 0.1 3.5 3 1 0 3 3 3 0 V-ATPase subunit H NmrA PF05368.13 KZN92450.1 - 1.9e-25 89.8 0.0 2.3e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KZN92450.1 - 1.2e-10 41.6 0.0 2.5e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KZN92450.1 - 1.9e-05 25.1 0.0 4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KZN92450.1 - 0.00031 20.0 0.0 0.00041 19.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KZN92450.1 - 0.00071 19.8 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DXP_reductoisom PF02670.16 KZN92450.1 - 0.0057 17.4 0.1 0.011 16.4 0.1 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3Beta_HSD PF01073.19 KZN92450.1 - 0.0058 15.7 0.0 0.0081 15.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KZN92450.1 - 0.0095 15.9 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KZN92450.1 - 0.018 14.5 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KZN92450.1 - 0.029 13.8 0.1 0.044 13.2 0.1 1.2 1 0 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.20 KZN92450.1 - 0.049 13.8 0.0 0.091 12.9 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PrpR_N PF06506.11 KZN92450.1 - 0.098 12.2 0.2 0.2 11.2 0.2 1.4 1 1 0 1 1 1 0 Propionate catabolism activator NAD_binding_4 PF07993.12 KZN92450.1 - 0.13 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Bac_rhamnosid6H PF17389.2 KZN92451.1 - 1.4e-15 57.4 6.0 6e-13 48.8 3.9 2.1 1 1 1 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KZN92451.1 - 1.5e-06 27.9 0.0 3.8e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Trehalase PF01204.18 KZN92451.1 - 0.00033 19.6 0.1 0.00049 19.0 0.1 1.1 1 0 0 1 1 1 1 Trehalase Bac_rhamnosid PF05592.11 KZN92451.1 - 0.15 12.1 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain Fe-ADH PF00465.19 KZN92452.1 - 9.6e-67 225.3 0.0 1.2e-66 225.0 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KZN92452.1 - 7.4e-09 35.7 0.0 0.00099 18.9 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DUF5451 PF17532.2 KZN92452.1 - 0.17 12.2 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5451) Chalcone_2 PF16035.5 KZN92453.1 - 3.5e-83 278.4 0.0 4.7e-83 278.0 0.0 1.2 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 KZN92453.1 - 0.00049 20.2 0.1 0.0021 18.2 0.0 1.9 2 0 0 2 2 2 1 Chalcone isomerase-like Glutaredoxin PF00462.24 KZN92454.1 - 9.4e-20 70.6 0.1 1.7e-19 69.8 0.0 1.4 2 0 0 2 2 2 1 Glutaredoxin DUF836 PF05768.14 KZN92454.1 - 0.00023 21.5 0.1 0.0003 21.1 0.1 1.3 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 KZN92454.1 - 0.0017 18.8 0.0 0.002 18.6 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 KZN92454.1 - 0.0093 15.9 0.0 0.012 15.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 KZN92454.1 - 0.018 14.9 0.1 0.13 12.0 0.1 1.9 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 KZN92454.1 - 0.028 14.5 0.0 0.039 14.0 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin domain TraF PF13728.6 KZN92454.1 - 0.047 13.5 0.0 0.049 13.4 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein BAG PF02179.16 KZN92456.1 - 1.3e-13 51.1 0.0 2.2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 KZN92456.1 - 0.00032 20.4 0.0 0.00054 19.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family YopE_N PF09020.10 KZN92456.1 - 0.17 12.1 7.4 0.66 10.2 1.3 2.3 2 0 0 2 2 2 0 YopE, N terminal LMBR1 PF04791.16 KZN92457.1 - 1.3e-131 440.0 2.2 1.5e-131 439.8 2.2 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein FUSC PF04632.12 KZN92457.1 - 0.037 12.6 7.3 0.01 14.4 1.0 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF2142 PF09913.9 KZN92457.1 - 0.16 10.8 12.0 35 3.1 12.0 2.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2142) Apolipoprotein PF01442.18 KZN92457.1 - 0.67 9.8 3.3 0.79 9.6 0.6 1.9 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Med15_fungi PF05397.12 KZN92458.1 - 2e-34 118.2 0.2 2e-34 118.2 0.2 5.1 5 0 0 5 5 5 1 Mediator complex subunit 15 KIX_2 PF16987.5 KZN92458.1 - 3.5e-09 36.5 1.0 3.5e-09 36.5 1.0 3.8 4 0 0 4 4 4 1 KIX domain Roughex PF06020.11 KZN92458.1 - 0.49 9.4 8.1 2 7.4 8.1 2.1 1 0 0 1 1 1 0 Drosophila roughex protein Vps39_1 PF10366.9 KZN92458.1 - 0.82 10.0 3.2 2.4 8.5 3.2 1.8 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Vma12 PF11712.8 KZN92458.1 - 7.3 6.7 6.8 40 4.3 6.8 2.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase EamA PF00892.20 KZN92459.1 - 4.2e-11 43.2 24.2 9.5e-06 25.8 2.7 2.6 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 KZN92459.1 - 1.3e-09 37.7 0.2 2e-09 37.0 0.2 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 KZN92459.1 - 9.8e-05 21.7 10.8 0.00027 20.2 10.6 1.9 2 1 0 2 2 2 1 UAA transporter family TPT PF03151.16 KZN92459.1 - 0.00059 19.3 2.5 0.00059 19.3 2.5 2.4 1 1 0 2 2 2 1 Triose-phosphate Transporter family CRT-like PF08627.10 KZN92459.1 - 0.023 13.7 14.4 0.13 11.1 8.4 3.5 2 1 1 3 3 3 0 CRT-like, chloroquine-resistance transporter-like DUF460 PF04312.13 KZN92459.1 - 0.032 13.9 0.2 0.059 13.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF460) Lyase_aromatic PF00221.19 KZN92459.1 - 0.043 12.5 0.1 0.061 12.0 0.1 1.1 1 0 0 1 1 1 0 Aromatic amino acid lyase CPP1-like PF11833.8 KZN92459.1 - 0.092 12.4 0.2 0.092 12.4 0.2 2.0 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Adaptin_N PF01602.20 KZN92460.1 - 1.1e-140 469.7 1.3 1.3e-140 469.5 1.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KZN92460.1 - 2.7e-17 63.1 0.0 5.1e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KZN92460.1 - 7.8e-08 32.5 7.0 0.00038 20.5 0.1 4.3 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KZN92460.1 - 4e-07 30.3 0.8 0.065 13.6 0.0 4.2 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 KZN92460.1 - 0.0017 18.4 0.9 6.7 7.3 0.1 4.4 3 0 0 3 3 3 1 HEAT repeat DUF3730 PF12530.8 KZN92460.1 - 0.0063 16.1 0.0 0.58 9.7 0.1 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF3730) Arm PF00514.23 KZN92460.1 - 0.072 13.2 0.8 1.3e+02 2.8 0.1 5.5 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat RICTOR_M PF14666.6 KZN92460.1 - 0.073 12.8 0.5 0.38 10.5 0.0 2.4 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain MBOAT PF03062.19 KZN92461.1 - 4.5e-37 128.2 21.4 2.5e-36 125.8 21.3 1.9 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family ALO PF04030.14 KZN92462.1 - 3.7e-09 36.8 0.3 4.8e-09 36.4 0.3 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase DnaJ PF00226.31 KZN92463.1 - 6e-18 64.7 0.6 6e-18 64.7 0.6 2.0 2 0 0 2 2 2 1 DnaJ domain DUF1447 PF07288.11 KZN92463.1 - 0.15 12.2 1.8 0.42 10.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1447) Metallophos PF00149.28 KZN92464.1 - 0.071 13.6 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Ribosomal_L13 PF00572.18 KZN92465.1 - 8e-12 45.5 0.1 8.9e-10 38.9 0.0 2.5 2 1 0 2 2 2 1 Ribosomal protein L13 DSBA PF01323.20 KZN92465.1 - 0.03 14.1 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain MOSC PF03473.17 KZN92466.1 - 7.6e-24 84.2 0.0 1.1e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KZN92466.1 - 3.6e-12 46.2 0.0 1.1e-11 44.6 0.0 1.7 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain AMP-binding PF00501.28 KZN92467.1 - 4.5e-73 246.2 0.0 5.4e-73 246.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KZN92467.1 - 8.4e-19 68.3 0.0 2e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LRR_6 PF13516.6 KZN92468.1 - 5.3e-14 51.0 21.0 1.4 9.2 0.0 11.7 12 0 0 12 12 12 6 Leucine Rich repeat F-box-like PF12937.7 KZN92468.1 - 1.8e-10 40.5 0.1 9.7e-10 38.2 0.0 2.4 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KZN92468.1 - 7.1e-08 32.6 14.5 1 9.9 0.1 7.9 4 2 6 10 10 10 5 Leucine Rich repeats (2 copies) DUF1699 PF08004.11 KZN92468.1 - 0.00076 19.2 0.9 0.085 12.5 0.0 3.4 3 2 1 4 4 4 1 Protein of unknown function (DUF1699) F-box PF00646.33 KZN92468.1 - 0.002 18.0 0.0 0.011 15.6 0.0 2.4 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.6 KZN92468.1 - 0.76 9.6 9.2 4 7.3 0.0 5.7 5 2 1 6 6 6 0 Leucine rich repeat Sugar_tr PF00083.24 KZN92469.1 - 3.9e-99 332.6 32.5 4.5e-99 332.3 32.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN92469.1 - 3.6e-27 95.2 19.7 3.6e-27 95.2 19.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KZN92469.1 - 6.8 6.4 11.8 0.25 11.1 3.9 2.5 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Glyco_hydro_32N PF00251.20 KZN92470.1 - 1.4e-33 116.8 3.5 2.2e-30 106.3 3.1 2.4 1 1 1 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KZN92470.1 - 1.6e-33 116.0 1.5 2.8e-33 115.2 1.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Oxidored_molyb PF00174.19 KZN92471.1 - 6.8e-41 139.7 0.0 1.1e-40 139.1 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Big_7 PF17957.1 KZN92471.1 - 0.0059 17.4 0.0 0.011 16.4 0.0 1.6 1 1 0 1 1 1 1 Bacterial Ig domain FMN_bind_2 PF04299.12 KZN92472.1 - 9.5e-59 197.9 0.1 1.1e-58 197.6 0.1 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain GATase PF00117.28 KZN92473.1 - 1.2e-09 38.2 0.0 1.8e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Aldedh PF00171.22 KZN92475.1 - 2.2e-145 484.7 0.6 2.5e-145 484.5 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF126 PF01989.16 KZN92475.1 - 0.027 14.2 2.2 1.7 8.5 0.2 3.6 4 0 0 4 4 4 0 Aconitase X swivel domain Sugar_tr PF00083.24 KZN92476.1 - 1.6e-100 337.1 24.2 1.9e-100 336.9 24.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN92476.1 - 4.1e-19 68.7 24.5 4.1e-19 68.7 24.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KZN92476.1 - 0.08 11.2 5.3 0.01 14.2 0.9 1.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.18 KZN92477.1 - 8.4e-16 57.8 0.0 1.2e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN92477.1 - 3.6e-06 27.0 15.4 9.2e-06 25.7 15.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TAXi_N PF14543.6 KZN92477.1 - 0.0083 16.4 0.7 0.014 15.6 0.7 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Herpes_US9 PF06072.11 KZN92477.1 - 0.18 11.7 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Transketolase_N PF00456.21 KZN92478.1 - 3.7e-108 361.4 0.0 5.1e-108 361.0 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KZN92478.1 - 1.2e-32 113.0 0.0 3.6e-32 111.5 0.0 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KZN92478.1 - 2.7e-12 46.7 0.0 1e-11 44.8 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KZN92478.1 - 1.8e-07 30.7 0.0 5.5e-07 29.1 0.0 1.8 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 KZN92478.1 - 0.00038 20.3 0.2 0.0013 18.5 0.2 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 KZN92478.1 - 0.028 13.4 0.1 0.051 12.5 0.1 1.4 1 0 0 1 1 1 0 Dehydrogenase E1 component ADH_N PF08240.12 KZN92479.1 - 6.7e-25 87.1 0.7 6.7e-25 87.1 0.7 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN92479.1 - 8.1e-14 51.7 0.3 1.5e-13 50.9 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KZN92479.1 - 6.6e-09 35.6 0.3 0.00075 19.0 0.1 2.7 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus HupF_HypC PF01455.18 KZN92479.1 - 0.017 15.2 0.5 1.5 9.0 0.1 2.5 2 0 0 2 2 2 0 HupF/HypC family AlaDh_PNT_C PF01262.21 KZN92479.1 - 0.12 11.7 0.7 0.23 10.8 0.7 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FMO-like PF00743.19 KZN92480.1 - 1.2e-13 50.4 0.1 6.4e-13 48.0 0.1 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KZN92480.1 - 1.9e-12 47.1 0.0 2.9e-11 43.2 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN92480.1 - 1.7e-11 44.2 0.0 4.1e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KZN92480.1 - 1.4e-08 34.4 0.0 9.5e-06 25.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KZN92480.1 - 1.1e-07 31.8 0.0 0.00015 21.5 0.0 3.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KZN92480.1 - 8.5e-07 28.4 0.1 9.5e-05 21.7 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KZN92480.1 - 0.0078 15.5 0.0 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KZN92480.1 - 0.021 14.8 0.4 0.9 9.5 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding GFO_IDH_MocA PF01408.22 KZN92481.1 - 1.3e-22 80.8 0.1 2.3e-22 80.1 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KZN92481.1 - 0.00033 20.6 0.1 0.00066 19.7 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_2 PF03446.15 KZN92481.1 - 0.0079 16.4 0.0 0.015 15.4 0.0 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short_C2 PF13561.6 KZN92482.1 - 4.7e-56 190.0 0.0 5.9e-56 189.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN92482.1 - 1.3e-42 145.4 0.0 1.7e-42 145.1 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN92482.1 - 8.1e-12 45.4 0.0 1.3e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KZN92482.1 - 0.0015 18.0 0.0 0.0025 17.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Thiol_cytolysin PF01289.19 KZN92483.1 - 0.016 14.1 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Thiol-activated cytolysin Arylsulfotran_2 PF14269.6 KZN92485.1 - 4.1e-18 65.8 0.0 5.1e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KZN92485.1 - 0.15 10.9 0.0 0.88 8.4 0.0 2.1 1 1 1 2 2 2 0 Arylsulfotransferase (ASST) NYN PF01936.18 KZN92486.1 - 1.5e-32 113.1 0.0 2.2e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.7 KZN92486.1 - 2.6e-18 65.6 0.0 5.4e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 OST-HTH/LOTUS domain DUF4965 PF16335.5 KZN92487.1 - 1.6e-33 115.8 0.0 3.4e-33 114.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KZN92487.1 - 2.9e-30 105.9 2.3 4.6e-30 105.2 2.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KZN92487.1 - 4.3e-07 29.4 0.0 1.1e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) DUF5127 PF17168.4 KZN92487.1 - 3.5e-06 27.0 0.0 8.3e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) MFS_1 PF07690.16 KZN92488.1 - 8.9e-34 116.9 59.8 2.5e-32 112.2 59.8 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KZN92488.1 - 1.4e-10 40.3 15.1 2.8e-10 39.2 15.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KZN92488.1 - 2.3e-09 36.6 33.9 7e-09 35.1 9.3 2.9 2 1 0 3 3 3 2 Sugar (and other) transporter Peptidase_M28 PF04389.17 KZN92489.1 - 1.3e-33 116.4 0.0 2e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KZN92489.1 - 0.0039 16.9 0.0 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 ATP-synt_8 PF00895.20 KZN92489.1 - 0.0093 16.4 0.6 0.0093 16.4 0.6 4.1 6 0 0 6 6 6 1 ATP synthase protein 8 Epimerase PF01370.21 KZN92491.1 - 2.4e-23 82.8 0.4 1.7e-22 80.1 0.4 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KZN92491.1 - 2.9e-14 53.2 0.0 4.7e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KZN92491.1 - 2.6e-08 33.4 0.0 1.6e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KZN92491.1 - 1.7e-07 31.3 0.0 3.5e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KZN92491.1 - 2.2e-07 30.2 0.0 6e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KZN92491.1 - 1.8e-06 27.3 0.0 2.7e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KZN92491.1 - 0.0081 15.3 0.0 0.036 13.2 0.0 2.0 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 KZN92491.1 - 0.1 12.5 0.1 0.65 9.9 0.1 2.1 1 1 0 1 1 1 0 KR domain NmrA PF05368.13 KZN92491.1 - 0.12 11.9 0.2 0.24 10.9 0.1 1.5 2 0 0 2 2 2 0 NmrA-like family Lipase_GDSL_2 PF13472.6 KZN92492.1 - 9.6e-20 71.7 0.1 1.2e-19 71.4 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.6 KZN92492.1 - 4.5e-05 23.7 0.0 0.017 15.3 0.0 2.7 3 0 0 3 3 3 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KZN92492.1 - 8.7e-05 22.6 0.0 0.0001 22.3 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Pro_racemase PF05544.11 KZN92494.1 - 1.5e-125 418.6 0.1 1.7e-125 418.4 0.1 1.0 1 0 0 1 1 1 1 Proline racemase CorA PF01544.18 KZN92495.1 - 2.2e-05 24.0 0.1 3.7e-05 23.2 0.1 1.3 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein AA_permease_2 PF13520.6 KZN92496.1 - 1.9e-46 158.8 52.1 2.3e-46 158.5 52.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN92496.1 - 2.5e-27 95.6 46.2 2.9e-27 95.4 46.2 1.0 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.8 KZN92497.1 - 3.1e-29 102.0 3.1 5.1e-29 101.3 3.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain FAA_hydrolase PF01557.18 KZN92498.1 - 9.5e-62 208.5 0.0 1.5e-61 207.9 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family MFS_1 PF07690.16 KZN92499.1 - 2.4e-28 99.1 16.9 2.4e-28 99.1 16.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KZN92499.1 - 0.0005 18.5 3.6 0.00059 18.3 2.2 1.9 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF1772 PF08592.11 KZN92499.1 - 0.042 14.2 7.2 3.6 7.9 0.1 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF1772) Fungal_trans PF04082.18 KZN92500.1 - 2.1e-17 63.0 0.1 4.3e-17 62.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tyrosinase PF00264.20 KZN92500.1 - 0.1 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Common central domain of tyrosinase DUF3535 PF12054.8 KZN92502.1 - 7e-127 424.3 0.0 3.1e-126 422.2 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KZN92502.1 - 6.6e-60 202.7 0.0 1.6e-59 201.4 0.0 1.5 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KZN92502.1 - 6.9e-19 68.2 0.0 1.8e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 KZN92502.1 - 1.6e-15 55.9 12.9 0.13 12.5 0.0 9.9 11 0 0 11 11 9 5 HEAT repeat Vac14_Fab1_bd PF12755.7 KZN92502.1 - 5.8e-07 30.0 0.0 0.057 14.0 0.0 4.0 3 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 KZN92502.1 - 1.3e-05 25.5 11.1 0.034 14.5 0.1 6.7 6 1 1 7 7 7 1 HEAT repeats Cnd1 PF12717.7 KZN92502.1 - 0.00011 22.2 0.0 0.15 12.1 0.0 4.6 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 TAF6_C PF07571.13 KZN92502.1 - 0.00062 20.0 0.0 2.5 8.5 0.0 4.7 5 0 0 5 5 5 1 TAF6 C-terminal HEAT repeat domain TIP120 PF08623.10 KZN92502.1 - 0.0033 17.2 0.0 3.1 7.5 0.0 3.6 3 1 1 4 4 4 1 TATA-binding protein interacting (TIP20) CLASP_N PF12348.8 KZN92502.1 - 0.021 14.4 0.2 12 5.4 0.0 3.9 4 1 1 5 5 5 0 CLASP N terminal HEAT_EZ PF13513.6 KZN92502.1 - 1 9.9 17.2 37 5.0 0.0 7.2 8 0 0 8 8 7 0 HEAT-like repeat Ndufs5 PF10200.9 KZN92503.1 - 0.001 19.2 0.0 0.0012 19.0 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa COX6B PF02297.17 KZN92503.1 - 0.0066 16.7 0.2 0.0094 16.2 0.2 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb DUF3128 PF11326.8 KZN92503.1 - 0.0079 16.5 1.1 0.056 13.8 1.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) CHCH PF06747.13 KZN92503.1 - 0.0095 16.1 0.1 0.015 15.5 0.1 1.3 1 0 0 1 1 1 1 CHCH domain Sec39 PF08314.11 KZN92504.1 - 1.6e-274 913.1 2.2 1.8e-274 912.9 2.2 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Pkinase PF00069.25 KZN92505.1 - 3.3e-64 216.8 0.0 4e-64 216.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN92505.1 - 8.5e-36 123.6 0.0 1.2e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KZN92505.1 - 1.3e-07 31.2 0.0 2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KZN92505.1 - 2.5e-05 23.2 0.0 3.8e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KZN92505.1 - 0.022 14.4 0.0 0.85 9.2 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KZN92505.1 - 0.089 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_1 PF00515.28 KZN92507.1 - 1.4e-34 116.5 13.7 7.1e-08 32.0 0.4 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 KZN92507.1 - 4.1e-34 113.9 11.7 2e-05 24.3 0.3 7.8 7 0 0 7 7 7 7 Tetratricopeptide repeat DnaJ PF00226.31 KZN92507.1 - 5.4e-27 93.7 1.1 1.9e-26 91.9 1.1 2.1 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.6 KZN92507.1 - 2.5e-20 72.8 14.5 9.9e-05 22.8 0.0 5.7 3 3 3 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 KZN92507.1 - 1.1e-19 70.8 6.9 4.6e-07 30.4 0.1 5.7 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 KZN92507.1 - 6.9e-19 66.4 9.2 8.2e-05 22.5 0.4 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 KZN92507.1 - 2.9e-16 58.7 9.7 0.032 15.0 0.1 8.1 2 2 6 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 KZN92507.1 - 5.3e-16 58.0 19.7 2.1e-08 33.7 0.9 7.4 6 2 2 8 8 7 4 TPR repeat ANAPC3 PF12895.7 KZN92507.1 - 2.8e-15 56.3 5.5 5.4e-06 26.5 0.0 5.0 2 2 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KZN92507.1 - 2.3e-13 49.5 16.5 0.0051 17.1 1.0 7.0 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KZN92507.1 - 1.6e-12 46.5 2.5 0.22 11.7 0.1 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KZN92507.1 - 3.9e-12 46.0 7.8 0.08 13.6 0.3 7.3 6 1 0 7 7 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 KZN92507.1 - 1.6e-11 44.3 9.6 0.0094 16.2 1.1 6.8 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 KZN92507.1 - 3.8e-10 39.8 7.5 0.0086 16.2 0.1 4.6 4 1 1 5 5 4 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KZN92507.1 - 1e-06 28.7 11.2 0.0095 16.0 0.2 5.4 5 1 1 6 6 6 2 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 KZN92507.1 - 1.4e-05 24.4 10.0 0.043 13.0 0.3 4.7 3 1 1 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 KZN92507.1 - 0.0014 19.1 3.0 6.5 7.7 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KZN92507.1 - 0.0015 19.0 5.3 5.4 7.5 0.5 4.3 2 2 2 4 4 4 1 Alkyl sulfatase dimerisation DUF928 PF06051.12 KZN92507.1 - 0.0018 18.2 0.2 0.2 11.5 0.1 2.5 2 0 0 2 2 2 1 Domain of Unknown Function (DUF928) Rapsyn_N PF10579.9 KZN92507.1 - 0.002 18.2 0.1 0.25 11.5 0.0 3.9 4 1 1 5 5 3 1 Rapsyn N-terminal myristoylation and linker region DUF3856 PF12968.7 KZN92507.1 - 0.0031 17.6 3.4 3.9 7.5 0.7 5.1 4 2 1 5 5 4 1 Domain of Unknown Function (DUF3856) BTAD PF03704.17 KZN92507.1 - 0.0078 16.7 3.3 0.71 10.3 0.3 3.8 2 1 1 3 3 3 1 Bacterial transcriptional activator domain DUF5588 PF17826.1 KZN92507.1 - 0.014 14.4 1.0 0.13 11.1 0.1 2.9 1 1 2 3 3 3 0 Family of unknown function (DUF5588) PPR PF01535.20 KZN92507.1 - 0.057 13.7 1.3 26 5.3 0.0 4.0 5 0 0 5 5 2 0 PPR repeat SHNi-TPR PF10516.9 KZN92507.1 - 0.085 12.3 2.6 5.2 6.6 0.0 4.3 5 0 0 5 5 5 0 SHNi-TPR TPR_20 PF14561.6 KZN92507.1 - 0.31 11.4 15.5 0.42 11.0 0.1 5.3 5 2 1 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KZN92507.1 - 0.36 10.8 16.7 3.9 7.5 0.3 6.8 8 0 0 8 8 8 0 Tetratricopeptide repeat MIT PF04212.18 KZN92507.1 - 0.59 10.2 9.6 18 5.5 0.3 4.7 2 1 2 4 4 4 0 MIT (microtubule interacting and transport) domain HEAT_2 PF13646.6 KZN92507.1 - 2 8.9 4.9 2.1 8.8 0.3 2.8 3 0 0 3 3 2 0 HEAT repeats Pkinase PF00069.25 KZN92509.1 - 3.5e-41 141.3 0.0 5e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN92509.1 - 1e-29 103.6 0.0 1.4e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KZN92509.1 - 0.1 12.5 0.0 11 5.9 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KZN92509.1 - 0.2 10.9 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Spt5_N PF11942.8 KZN92509.1 - 6.1 7.9 8.3 0.92 10.5 1.8 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Med10 PF09748.9 KZN92510.1 - 2e-43 147.2 0.0 2.3e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.7 KZN92510.1 - 0.067 13.1 0.0 0.073 12.9 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) Fungal_trans PF04082.18 KZN92511.1 - 1.1e-23 83.6 1.6 1.9e-23 82.8 1.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain tRNA_lig_kinase PF08303.11 KZN92511.1 - 0.21 11.7 0.3 0.88 9.6 0.3 1.9 1 1 0 1 1 1 0 tRNA ligase kinase domain HpcH_HpaI PF03328.14 KZN92512.1 - 6.9e-35 120.2 0.0 8e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family ILVD_EDD PF00920.21 KZN92513.1 - 1e-156 522.6 0.0 1.2e-156 522.4 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family Erythro_esteras PF05139.14 KZN92514.1 - 1.2e-123 413.3 3.3 1.4e-123 413.1 3.3 1.0 1 0 0 1 1 1 1 Erythromycin esterase Cofac_haem_bdg PF04187.13 KZN92514.1 - 0.0033 17.5 0.3 0.034 14.1 0.3 2.1 1 1 0 1 1 1 1 Haem-binding uptake, Tiki superfamily, ChaN Scs3p PF10261.9 KZN92516.1 - 2.8e-73 246.5 2.7 3.5e-73 246.1 2.7 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Mito_carr PF00153.27 KZN92517.1 - 1.3e-35 121.2 0.6 6.4e-20 70.9 0.1 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF4579 PF15158.6 KZN92517.1 - 0.21 11.3 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4579) GTP_EFTU PF00009.27 KZN92518.1 - 5.6e-30 104.3 2.9 1.9e-28 99.3 2.9 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KZN92518.1 - 2.3e-28 98.4 1.9 7.6e-28 96.7 0.8 2.2 2 0 0 2 2 2 1 Translation-initiation factor 2 IF2_N PF04760.15 KZN92518.1 - 1.4e-09 37.6 0.0 3.9e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.23 KZN92518.1 - 2.7e-09 37.1 0.5 8e-09 35.6 0.1 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KZN92518.1 - 0.00018 21.5 0.3 0.072 13.0 0.0 2.5 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KZN92518.1 - 0.0074 15.7 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit zf-RanBP PF00641.18 KZN92518.1 - 0.063 12.6 4.6 0.13 11.6 4.6 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others zf-C3HC4_3 PF13920.6 KZN92518.1 - 0.3 11.0 2.3 0.6 10.0 2.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UPF0547 PF10571.9 KZN92518.1 - 1.5 9.0 6.2 3.3 7.9 6.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 Zn_clus PF00172.18 KZN92519.1 - 2e-08 34.2 9.4 2e-08 34.2 9.4 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN92519.1 - 0.00019 20.6 0.0 0.001 18.2 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain NPF PF16601.5 KZN92519.1 - 0.12 12.8 0.3 0.12 12.8 0.3 2.1 2 0 0 2 2 2 0 Rabosyn-5 repeating NPF sequence-motif EI24 PF07264.11 KZN92520.1 - 1e-14 55.2 14.4 1.3e-14 54.8 14.4 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) HAD_2 PF13419.6 KZN92521.1 - 1.4e-07 31.8 0.0 2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KZN92521.1 - 3.6e-07 30.2 0.0 5.2e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 HAD-hyrolase-like Trypan_PARP PF05887.11 KZN92523.1 - 0.053 13.5 75.6 0.024 14.6 31.1 3.4 2 1 1 3 3 3 0 Procyclic acidic repetitive protein (PARP) Ceramidase_alk PF04734.13 KZN92524.1 - 1.1e-210 700.6 0.0 1.3e-210 700.4 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KZN92524.1 - 3.2e-59 199.6 0.0 4.9e-59 199.0 0.0 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal BCAS2 PF05700.11 KZN92525.1 - 4.8e-63 212.6 9.5 5.6e-63 212.4 9.5 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) ISG65-75 PF11727.8 KZN92525.1 - 0.016 14.5 1.1 0.023 13.9 1.1 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein ACCA PF03255.14 KZN92525.1 - 0.021 14.7 2.5 0.038 13.9 2.5 1.3 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 3Beta_HSD PF01073.19 KZN92526.1 - 4.1e-26 91.6 0.0 1.1e-25 90.2 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KZN92526.1 - 8.1e-11 41.8 0.0 1.6e-10 40.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KZN92526.1 - 3.6e-10 39.5 0.0 4.1e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 KZN92526.1 - 2.8e-06 27.3 0.0 2.1e-05 24.5 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KZN92526.1 - 8.4e-05 21.8 0.0 0.00013 21.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KZN92526.1 - 0.0016 17.6 0.0 0.05 12.7 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KZN92526.1 - 0.0017 17.8 0.0 0.0031 17.0 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase MFS_1 PF07690.16 KZN92527.1 - 5.7e-41 140.6 32.2 5.7e-41 140.6 32.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN92527.1 - 1.5e-14 53.7 12.6 3.8e-14 52.4 12.6 1.7 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KZN92527.1 - 2.1e-08 33.1 6.7 3.6e-08 32.3 6.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KZN92527.1 - 0.03 12.7 8.2 0.018 13.4 5.3 1.9 2 0 0 2 2 2 0 Transmembrane secretion effector Ten1 PF12658.7 KZN92528.1 - 3.1e-46 156.3 0.0 3.5e-46 156.1 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.6 KZN92528.1 - 0.06 13.1 0.0 0.087 12.5 0.0 1.2 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit Snf7 PF03357.21 KZN92529.1 - 1.6e-35 122.2 17.3 1.6e-35 122.2 17.3 2.0 1 1 1 2 2 2 1 Snf7 DUF3573 PF12097.8 KZN92529.1 - 0.87 8.3 2.5 1.3 7.8 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) NuA4 PF09340.10 KZN92529.1 - 3 7.8 7.4 0.48 10.3 0.3 3.0 3 0 0 3 3 3 0 Histone acetyltransferase subunit NuA4 DUF3138 PF11336.8 KZN92529.1 - 4.9 5.7 8.7 6.9 5.2 8.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) CRC_subunit PF08624.10 KZN92530.1 - 3.5e-51 173.2 0.0 5.1e-51 172.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Pkinase PF00069.25 KZN92531.1 - 4.3e-69 232.8 0.0 5.8e-69 232.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN92531.1 - 6.8e-31 107.5 0.0 1e-30 106.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KZN92531.1 - 3.7e-13 49.9 0.4 3.7e-13 49.9 0.4 3.1 2 1 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 KZN92531.1 - 3e-09 37.1 0.0 6.8e-08 32.7 0.0 2.5 2 0 0 2 2 2 1 C2 domain Kinase-like PF14531.6 KZN92531.1 - 1.2e-08 34.7 0.1 7.1e-08 32.1 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KZN92531.1 - 1.4e-05 24.2 0.1 3e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KZN92531.1 - 0.004 17.1 0.0 0.0077 16.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Adeno_E3_15_3 PF03307.14 KZN92531.1 - 0.012 15.6 0.1 0.023 14.7 0.1 1.3 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region Choline_kinase PF01633.20 KZN92531.1 - 0.059 12.9 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ank_2 PF12796.7 KZN92532.1 - 2.2e-14 53.8 0.0 0.00011 22.7 0.0 3.5 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KZN92532.1 - 2.8e-13 48.7 0.6 0.00041 20.6 0.0 5.6 5 1 1 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 KZN92532.1 - 2.7e-11 43.8 1.0 0.0056 17.2 0.0 4.5 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KZN92532.1 - 4.6e-08 33.2 0.3 0.0071 16.6 0.0 3.5 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KZN92532.1 - 4.6e-08 33.1 0.5 0.0027 18.1 0.0 4.8 4 1 0 4 4 4 2 Ankyrin repeat FadR_C PF07840.12 KZN92532.1 - 0.028 14.3 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 FadR C-terminal domain F-box PF00646.33 KZN92534.1 - 0.0036 17.1 0.0 0.0098 15.8 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KZN92534.1 - 0.0082 16.0 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 KZN92534.1 - 0.046 13.5 1.2 0.15 11.8 1.2 1.9 1 0 0 1 1 1 0 Leucine rich repeat tRNA-synt_1c PF00749.21 KZN92535.1 - 3.1e-102 341.7 0.0 4.2e-102 341.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KZN92535.1 - 2.2e-31 109.1 0.0 7.1e-31 107.4 0.0 1.9 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain THUMP PF02926.17 KZN92535.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 THUMP domain AAA PF00004.29 KZN92536.1 - 1.3e-40 138.8 0.0 2.6e-40 137.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KZN92536.1 - 6.9e-19 67.6 0.2 1.4e-18 66.6 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KZN92536.1 - 3.4e-09 36.4 0.0 7.7e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KZN92536.1 - 6e-05 23.1 0.1 0.00028 20.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KZN92536.1 - 6.4e-05 22.8 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KZN92536.1 - 0.00017 22.0 1.3 0.022 15.1 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 KZN92536.1 - 0.004 16.4 0.0 0.011 14.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KZN92536.1 - 0.0051 17.1 2.0 0.2 11.9 0.0 2.9 2 1 1 3 3 3 1 AAA domain PhoH PF02562.16 KZN92536.1 - 0.0052 16.3 0.2 0.079 12.4 0.1 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 KZN92536.1 - 0.0076 15.6 0.1 0.021 14.2 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 KZN92536.1 - 0.0078 16.3 3.6 0.012 15.7 0.0 3.0 3 2 1 4 4 3 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KZN92536.1 - 0.014 15.5 0.0 0.043 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KZN92536.1 - 0.07 12.9 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein JIP_LZII PF16471.5 KZN92536.1 - 0.24 11.6 6.0 0.61 10.3 6.0 1.8 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II AAA_11 PF13086.6 KZN92536.1 - 0.43 10.3 0.0 0.43 10.3 0.0 2.9 2 1 1 3 3 2 0 AAA domain Atg14 PF10186.9 KZN92536.1 - 0.72 8.9 5.7 2.3 7.2 5.2 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 CLZ PF16526.5 KZN92536.1 - 2.8 8.4 11.4 0.62 10.5 6.8 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RPN2_C PF18004.1 KZN92536.1 - 8 6.4 8.7 19 5.1 8.7 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain TauD PF02668.16 KZN92537.1 - 4e-36 125.2 1.1 5.7e-36 124.7 1.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KZN92537.1 - 3.8e-13 49.9 0.0 1.1e-12 48.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.10 KZN92537.1 - 0.0064 15.7 0.1 0.017 14.2 0.1 1.6 1 1 0 1 1 1 1 CsiD MaoC_dehydratas PF01575.19 KZN92538.1 - 4.3e-23 81.2 0.0 8.1e-23 80.3 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KZN92538.1 - 5.3e-05 23.4 0.0 0.052 13.7 0.0 2.5 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase Per1 PF04080.13 KZN92539.1 - 2.7e-102 341.9 13.3 3.3e-102 341.6 13.3 1.1 1 0 0 1 1 1 1 Per1-like family PGM_PMM_IV PF00408.20 KZN92540.1 - 1.8e-11 44.0 0.3 5.5e-11 42.5 0.3 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_I PF02878.16 KZN92540.1 - 1.5e-05 24.8 0.0 4.2e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KZN92540.1 - 0.00058 20.0 0.2 0.0033 17.6 0.2 2.1 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KZN92540.1 - 0.00059 20.4 1.1 0.0051 17.4 0.6 2.7 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DEAD PF00270.29 KZN92541.1 - 1.7e-45 155.0 0.0 2.4e-45 154.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KZN92541.1 - 8.7e-29 100.1 0.0 2.3e-28 98.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KZN92541.1 - 8.3e-05 21.9 0.0 0.00017 20.9 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KZN92541.1 - 0.00015 21.9 0.0 0.00029 20.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Brix PF04427.18 KZN92542.1 - 3.4e-50 170.8 0.8 4.9e-50 170.3 0.8 1.2 1 0 0 1 1 1 1 Brix domain Lum_binding PF00677.17 KZN92543.1 - 7.2e-43 144.5 1.5 6.7e-22 77.3 0.5 2.2 2 0 0 2 2 2 2 Lumazine binding domain CoA_transf_3 PF02515.17 KZN92544.1 - 8.8e-128 426.5 0.0 1e-127 426.3 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III GxDLY PF14607.6 KZN92544.1 - 0.11 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 N-terminus of Esterase_SGNH_hydro-type 2OG-FeII_Oxy_3 PF13640.6 KZN92545.1 - 3.2e-08 34.3 0.0 9.1e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.25 KZN92546.1 - 4.8e-31 107.7 0.1 8.3e-31 107.0 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN92546.1 - 3.3e-22 79.2 0.1 5.4e-22 78.5 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN92546.1 - 3.8e-09 36.7 0.3 6.8e-09 35.9 0.3 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KZN92546.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Sof1 PF04158.14 KZN92547.1 - 2.2e-31 107.9 14.4 4.2e-31 107.0 14.4 1.5 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KZN92547.1 - 1.6e-30 104.6 3.1 8.5e-06 26.4 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN92547.1 - 8.6e-09 35.6 0.2 0.096 13.0 0.0 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KZN92547.1 - 2.7e-05 23.3 0.1 0.023 13.7 0.0 3.0 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KZN92547.1 - 0.0016 18.3 0.3 0.0058 16.5 0.1 2.0 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A DUF1481 PF07356.12 KZN92547.1 - 0.067 13.0 0.0 0.21 11.3 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1481) BBP1_N PF15271.6 KZN92547.1 - 0.12 13.2 0.5 0.24 12.2 0.5 1.4 1 0 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein RPN6_N PF18055.1 KZN92548.1 - 5.5e-43 146.0 0.7 5e-42 143.0 0.0 2.7 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KZN92548.1 - 6.9e-21 74.7 1.7 1.3e-20 73.9 0.2 2.3 2 1 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 KZN92548.1 - 3.4e-11 42.7 1.1 5e-11 42.1 0.1 1.9 2 0 0 2 2 2 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_12 PF13424.6 KZN92548.1 - 3.9e-06 27.1 17.3 0.059 13.7 5.9 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat DDRGK PF09756.9 KZN92548.1 - 3.7e-05 23.4 0.6 6.5e-05 22.6 0.6 1.4 1 0 0 1 1 1 1 DDRGK domain TPR_MalT PF17874.1 KZN92548.1 - 0.0002 20.9 4.0 0.00057 19.4 4.0 1.8 1 0 0 1 1 1 1 MalT-like TPR region HTH_Crp_2 PF13545.6 KZN92548.1 - 0.0015 18.4 0.1 0.41 10.7 0.0 2.9 2 1 0 2 2 2 1 Crp-like helix-turn-helix domain DUF410 PF04190.13 KZN92548.1 - 0.0076 16.1 0.2 0.0076 16.1 0.2 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF410) TPR_14 PF13428.6 KZN92548.1 - 0.023 15.5 11.1 52 5.0 0.7 6.0 5 1 1 6 6 5 0 Tetratricopeptide repeat DprA_WH PF17782.1 KZN92548.1 - 0.049 13.7 1.2 0.43 10.7 0.0 3.0 3 1 1 4 4 4 0 DprA winged helix domain Soyouz_module PF14313.6 KZN92548.1 - 0.061 13.1 0.2 0.39 10.5 0.0 2.4 3 0 0 3 3 3 0 N-terminal region of Paramyxovirinae phosphoprotein (P) DUF4398 PF14346.6 KZN92548.1 - 0.076 13.7 5.7 2 9.1 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) TPR_7 PF13176.6 KZN92548.1 - 0.082 13.0 5.0 1.8 8.8 0.1 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Prefoldin_2 PF01920.20 KZN92548.1 - 0.083 12.9 2.2 0.18 11.8 0.6 2.4 2 0 0 2 2 2 0 Prefoldin subunit DUF3496 PF12001.8 KZN92548.1 - 0.14 12.5 0.9 1.3 9.4 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) TPR_2 PF07719.17 KZN92548.1 - 0.18 12.0 10.1 9 6.7 0.1 5.5 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KZN92548.1 - 0.59 10.9 5.2 80 4.2 0.3 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KZN92548.1 - 8.6 6.4 10.1 14 5.7 0.0 5.0 7 0 0 7 7 7 0 Tetratricopeptide repeat SWIB PF02201.18 KZN92549.1 - 1.7e-23 82.3 0.0 3e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain TRAM_LAG1_CLN8 PF03798.16 KZN92550.1 - 2.8e-55 187.1 15.1 4.1e-55 186.6 15.1 1.2 1 0 0 1 1 1 1 TLC domain Pkinase PF00069.25 KZN92551.1 - 5e-15 55.6 0.0 9.1e-15 54.7 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN92551.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase SAP30_Sin3_bdg PF13867.6 KZN92552.1 - 0.0018 18.5 1.5 5.8 7.3 0.0 5.2 5 0 0 5 5 5 2 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF5339 PF17274.2 KZN92552.1 - 0.16 12.8 6.0 5.6 7.9 0.7 5.5 5 0 0 5 5 5 0 Family of unknown function (DUF5339) NAT PF04768.13 KZN92552.1 - 0.31 10.7 2.2 0.82 9.3 0.2 2.7 2 0 0 2 2 2 0 NAT, N-acetyltransferase, of N-acetylglutamate synthase Scaffolding_pro PF11418.8 KZN92552.1 - 3.9 8.1 10.4 0.28 11.8 1.1 4.1 4 0 0 4 4 4 0 Phi29 scaffolding protein DUF2730 PF10805.8 KZN92552.1 - 7.8 6.6 17.1 0.026 14.6 0.8 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF2730) Ribosomal_L27e PF01777.18 KZN92553.1 - 9.1e-37 125.3 1.1 1.4e-36 124.7 1.1 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KZN92553.1 - 0.014 15.3 2.0 0.027 14.4 0.9 2.1 2 0 0 2 2 2 0 KOW motif TCL1_MTCP1 PF01840.17 KZN92554.1 - 0.026 14.2 0.4 0.052 13.2 0.4 1.5 1 0 0 1 1 1 0 TCL1/MTCP1 family MAGE PF01454.19 KZN92556.1 - 1.2e-60 204.8 0.0 1.8e-60 204.3 0.0 1.3 1 0 0 1 1 1 1 MAGE family GTP_EFTU PF00009.27 KZN92557.1 - 2.7e-54 183.7 0.0 4e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KZN92557.1 - 3.2e-42 143.3 0.0 8.9e-42 141.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KZN92557.1 - 2.6e-12 46.9 0.5 7.7e-12 45.4 0.5 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KZN92557.1 - 0.00018 21.6 0.2 0.0043 17.1 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KZN92557.1 - 0.028 14.3 0.7 0.084 12.8 0.7 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 4 Semialdhyde_dhC PF02774.18 KZN92557.1 - 0.03 14.4 0.2 0.32 11.0 0.1 2.2 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain FlpD PF02662.16 KZN92557.1 - 0.04 13.9 0.0 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit DNA_meth_N PF18284.1 KZN92557.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 DNA methylase N-terminal domain G-alpha PF00503.20 KZN92557.1 - 0.24 10.5 0.2 1.3 8.1 0.0 2.0 1 1 1 2 2 2 0 G-protein alpha subunit TFIIS_C PF01096.18 KZN92558.1 - 5.3e-20 71.0 2.4 5.3e-20 71.0 2.4 3.0 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KZN92558.1 - 4.3e-08 32.9 5.8 5e-07 29.5 2.2 3.2 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit IBR PF01485.21 KZN92558.1 - 0.0017 18.5 5.3 0.54 10.5 0.7 2.4 2 1 0 2 2 2 2 IBR domain, a half RING-finger domain Zn_ribbon_recom PF13408.6 KZN92558.1 - 0.036 14.6 0.2 1.8 9.1 0.0 2.4 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zinc_ribbon_4 PF13717.6 KZN92558.1 - 0.074 13.0 7.8 1.7 8.6 0.2 3.0 3 1 0 3 3 3 0 zinc-ribbon domain PriA_CRR PF18319.1 KZN92558.1 - 0.095 12.7 1.8 2.8 8.0 0.1 3.0 3 0 0 3 3 3 0 PriA DNA helicase Cys-rich region (CRR) domain TF_Zn_Ribbon PF08271.12 KZN92558.1 - 0.87 9.2 7.1 3.1 7.4 0.4 2.9 3 1 0 3 3 3 0 TFIIB zinc-binding zf-H2C2_2 PF13465.6 KZN92558.1 - 1.1 9.8 6.9 5.1 7.7 0.1 3.6 4 0 0 4 4 4 0 Zinc-finger double domain DZR PF12773.7 KZN92558.1 - 1.5 8.9 7.4 0.9 9.6 0.4 2.7 2 1 0 2 2 2 0 Double zinc ribbon zf-TFIIB PF13453.6 KZN92558.1 - 4.6 6.7 8.4 0.71 9.3 0.7 2.9 3 0 0 3 3 3 0 Transcription factor zinc-finger Ank_3 PF13606.6 KZN92559.1 - 3.4e-08 33.1 0.0 0.0075 16.7 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KZN92559.1 - 2.1e-07 31.4 0.1 8.4e-07 29.5 0.1 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KZN92559.1 - 4.6e-06 26.8 0.2 0.0099 16.2 0.0 3.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KZN92559.1 - 6e-05 23.3 0.0 0.031 14.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KZN92559.1 - 0.0011 19.5 0.0 0.0022 18.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) PPR_long PF17177.4 KZN92559.1 - 0.065 12.6 0.0 0.089 12.2 0.0 1.4 1 1 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KZN92559.1 - 0.47 10.8 1.8 56 4.3 0.0 3.1 3 0 0 3 3 3 0 PPR repeat ALG11_N PF15924.5 KZN92560.1 - 1.8e-83 279.7 0.0 2.9e-83 279.1 0.0 1.3 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KZN92560.1 - 7.3e-21 74.4 0.0 1.2e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KZN92560.1 - 1.4e-10 41.7 0.0 4.4e-10 40.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KZN92560.1 - 1.5e-05 25.1 0.0 6.3e-05 23.0 0.0 2.1 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KZN92560.1 - 0.023 15.1 0.1 0.054 13.9 0.1 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KZN92560.1 - 0.083 13.3 0.6 0.31 11.5 0.0 2.2 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain 60KD_IMP PF02096.20 KZN92561.1 - 2.1e-09 37.5 0.0 2.7e-09 37.1 0.0 1.3 1 1 0 1 1 1 1 60Kd inner membrane protein PP2C PF00481.21 KZN92562.1 - 3.5e-43 148.1 0.0 6.7e-43 147.2 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KZN92562.1 - 0.00037 20.2 0.0 0.00069 19.3 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KZN92562.1 - 0.0078 16.1 0.0 2.3 8.1 0.0 2.7 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) Tcf25 PF04910.14 KZN92563.1 - 1e-76 258.3 0.0 1.3e-76 257.9 0.0 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TonB_N PF16031.5 KZN92563.1 - 0.043 14.3 16.0 0.089 13.3 16.0 1.5 1 0 0 1 1 1 0 TonB polyproline region CDC45 PF02724.14 KZN92563.1 - 6.9 4.8 6.0 9.6 4.4 6.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Metallophos PF00149.28 KZN92564.1 - 1.2e-12 48.8 0.4 1.6e-12 48.4 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KZN92564.1 - 8.8e-11 42.3 0.7 3.4e-07 30.6 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Transp_inhibit PF18791.1 KZN92564.1 - 0.068 12.7 0.2 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 Transport inhibitor response 1 protein domain HNH_2 PF13391.6 KZN92565.1 - 4.3e-16 58.8 0.0 9.6e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease PQ-loop PF04193.14 KZN92566.1 - 1.5e-20 72.7 0.2 1.5e-20 72.7 0.2 1.6 2 0 0 2 2 2 1 PQ loop repeat MASE1 PF05231.14 KZN92566.1 - 0.0087 15.2 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 1 MASE1 DUF4190 PF13828.6 KZN92566.1 - 0.33 10.7 2.0 0.47 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) Ribosomal_60s PF00428.19 KZN92567.1 - 4.9e-25 87.9 10.3 5.8e-25 87.7 10.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2408 PF10303.9 KZN92568.1 - 1.6e-44 151.8 8.3 1.8e-28 99.7 1.5 5.1 3 2 1 4 4 4 3 Protein of unknown function (DUF2408) Spc7 PF08317.11 KZN92568.1 - 0.00037 19.5 0.8 0.00078 18.4 0.8 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein FPP PF05911.11 KZN92568.1 - 0.0011 17.3 1.1 0.0015 16.9 1.1 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil DNA_pol_phi PF04931.13 KZN92568.1 - 0.003 15.7 1.2 0.0042 15.3 1.2 1.1 1 0 0 1 1 1 1 DNA polymerase phi DUF2383 PF09537.10 KZN92568.1 - 0.062 13.7 0.2 0.19 12.1 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) PTRF_SDPR PF15237.6 KZN92568.1 - 0.08 12.6 0.5 0.2 11.3 0.5 1.5 1 0 0 1 1 1 0 PTRF/SDPR family FRB_dom PF08771.11 KZN92568.1 - 0.1 13.0 0.5 4.4 7.8 0.1 2.7 1 1 1 2 2 2 0 FKBP12-rapamycin binding domain Snapin_Pallidin PF14712.6 KZN92568.1 - 0.1 13.0 5.6 0.54 10.7 0.7 4.1 4 0 0 4 4 4 0 Snapin/Pallidin DUF3659 PF12396.8 KZN92568.1 - 0.26 11.2 1.3 0.91 9.5 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3659) Baculo_PEP_C PF04513.12 KZN92568.1 - 0.57 10.2 2.5 0.83 9.7 1.0 2.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.11 KZN92568.1 - 0.99 9.6 7.2 0.34 11.1 4.0 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Prefoldin_2 PF01920.20 KZN92568.1 - 1.9 8.5 7.9 9.7 6.2 0.1 3.6 3 1 1 4 4 4 0 Prefoldin subunit Zap1_zf2 PF18217.1 KZN92569.1 - 1.1 9.3 6.3 0.78 9.8 0.2 2.9 2 1 0 2 2 2 0 Zap1 zinc finger 2 Aconitase PF00330.20 KZN92570.1 - 2.4e-143 478.5 0.0 3e-143 478.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KZN92570.1 - 1.3e-38 132.2 0.0 2.1e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2 PF00096.26 KZN92571.1 - 1.8e-12 47.0 12.6 3.9e-06 27.0 2.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KZN92571.1 - 6.4e-12 45.3 9.7 2e-07 31.1 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KZN92571.1 - 1e-08 35.3 10.4 0.00043 20.9 1.5 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KZN92571.1 - 4e-08 33.1 5.4 0.00034 20.5 0.3 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KZN92571.1 - 4.1e-06 26.9 0.4 0.094 13.0 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KZN92571.1 - 4.2e-05 23.8 0.8 0.014 15.8 0.2 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KZN92571.1 - 0.0064 16.2 4.8 0.44 10.4 0.7 3.4 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-Di19 PF05605.12 KZN92571.1 - 0.091 13.1 1.4 0.19 12.0 1.4 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_recom PF13408.6 KZN92571.1 - 0.19 12.3 0.9 0.45 11.1 0.9 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C2HE PF16278.5 KZN92571.1 - 0.36 11.3 1.9 12 6.5 0.3 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger LIM PF00412.22 KZN92571.1 - 0.66 10.2 2.9 19 5.6 0.1 2.6 1 1 1 2 2 2 0 LIM domain C5HCH PF17982.1 KZN92571.1 - 5.6 7.2 6.0 30 4.9 0.4 2.6 1 1 1 2 2 2 0 NSD Cys-His rich domain Glyco_hydro_53 PF07745.13 KZN92572.1 - 1.8e-103 346.1 0.1 2e-103 345.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Pkinase PF00069.25 KZN92573.1 - 7.8e-52 176.2 0.3 2e-34 119.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KZN92573.1 - 7.7e-27 94.2 0.0 2.3e-25 89.4 0.0 3.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KZN92573.1 - 0.00027 19.8 0.6 0.001 17.9 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KZN92573.1 - 0.002 18.1 0.4 0.019 14.9 0.4 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KZN92573.1 - 0.0044 16.4 0.0 0.014 14.7 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Myb_DNA-binding PF00249.31 KZN92574.1 - 1.1e-26 92.7 2.4 1.7e-15 57.0 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KZN92574.1 - 1.1e-17 64.0 7.4 9.3e-15 54.6 0.1 2.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain DUF2774 PF11242.8 KZN92574.1 - 0.016 15.4 0.0 0.041 14.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) Myb_DNA-bind_4 PF13837.6 KZN92574.1 - 0.08 13.3 1.2 0.3 11.5 0.1 2.2 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Glyco_transf_41 PF13844.6 KZN92575.1 - 4e-104 348.7 0.0 9.5e-53 179.3 0.0 3.1 2 1 1 3 3 3 3 Glycosyl transferase family 41 TPR_1 PF00515.28 KZN92575.1 - 2.2e-17 62.0 3.4 5.3e-05 22.9 0.0 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 KZN92575.1 - 2.1e-15 56.1 7.0 4.9e-05 22.9 0.1 6.2 3 2 3 6 6 6 3 TPR repeat TPR_2 PF07719.17 KZN92575.1 - 7e-15 53.9 8.6 0.033 14.3 0.0 6.0 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 KZN92575.1 - 4.3e-13 48.3 1.5 0.00026 21.0 0.1 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 KZN92575.1 - 1.5e-08 34.5 2.9 0.68 10.4 0.2 5.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KZN92575.1 - 2.2e-08 33.7 11.9 0.025 14.4 0.1 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KZN92575.1 - 9.4e-08 32.2 7.3 0.021 15.1 0.2 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KZN92575.1 - 2.1e-07 31.2 10.2 0.53 11.2 0.0 6.2 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KZN92575.1 - 6.4e-07 29.8 7.7 0.021 15.3 0.2 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KZN92575.1 - 7.9e-06 25.5 3.1 0.86 9.8 0.1 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KZN92575.1 - 0.00027 21.5 10.2 0.51 11.0 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KZN92575.1 - 0.024 14.9 0.8 0.15 12.3 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KZN92575.1 - 0.027 14.6 6.1 0.057 13.6 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 KZN92575.1 - 0.035 13.3 0.4 0.72 9.0 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 KZN92575.1 - 0.083 13.3 2.7 0.76 10.2 0.0 2.9 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_4 PF07721.14 KZN92575.1 - 8.7 7.3 6.4 71 4.5 0.6 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L11_N PF03946.14 KZN92576.1 - 2.3e-24 85.0 0.1 3.8e-24 84.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KZN92576.1 - 3.9e-15 56.1 0.3 5.6e-15 55.6 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Sec23_trunk PF04811.15 KZN92577.1 - 7.2e-82 274.6 0.0 1e-81 274.1 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KZN92577.1 - 9.9e-30 103.2 0.0 2e-29 102.1 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KZN92577.1 - 1.8e-24 85.5 0.0 4.3e-24 84.3 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KZN92577.1 - 9e-16 57.6 3.3 1.8e-15 56.7 3.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KZN92577.1 - 2.2e-11 43.5 0.0 5.5e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KZN92577.1 - 0.029 13.8 0.2 0.066 12.6 0.2 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DNA_primase_lrg PF04104.14 KZN92578.1 - 3.8e-90 301.9 0.0 5.2e-90 301.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit ADK PF00406.22 KZN92579.1 - 2.4e-35 121.9 0.0 1.1e-19 71.1 0.0 2.1 1 1 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.14 KZN92579.1 - 5.4e-16 58.3 0.0 8.7e-16 57.6 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 KZN92579.1 - 3.3e-15 56.7 0.0 4.6e-10 40.1 0.0 2.6 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 KZN92579.1 - 1.4e-05 25.7 0.0 7.2e-05 23.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KZN92579.1 - 0.00086 19.5 0.3 0.0082 16.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain DUF3446 PF11928.8 KZN92579.1 - 0.03 14.6 5.0 0.054 13.8 5.0 1.4 1 0 0 1 1 1 0 Early growth response N-terminal domain AAA_28 PF13521.6 KZN92579.1 - 0.041 14.1 0.0 0.079 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KZN92579.1 - 0.066 13.2 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Guanylate_kin PF00625.21 KZN92579.1 - 0.16 11.6 0.1 2.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Guanylate kinase SNase PF00565.17 KZN92580.1 - 2.4e-21 76.2 0.0 3.3e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue F-box-like PF12937.7 KZN92581.1 - 4.4e-08 32.9 0.1 9.7e-08 31.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN92581.1 - 4e-06 26.6 0.1 9.4e-06 25.4 0.1 1.5 1 0 0 1 1 1 1 F-box domain DnaJ PF00226.31 KZN92582.1 - 1.8e-18 66.4 0.1 4.7e-18 65.1 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain ATP-synt PF00231.19 KZN92583.1 - 7.8e-76 255.4 5.9 9.5e-76 255.2 5.9 1.0 1 0 0 1 1 1 1 ATP synthase Topoisom_I_N PF02919.15 KZN92584.1 - 4.3e-96 320.5 2.8 4.3e-96 320.5 2.8 4.1 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 KZN92584.1 - 7.8e-95 316.5 7.0 7.8e-95 316.5 7.0 2.1 2 1 1 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 KZN92584.1 - 6.4e-34 115.7 1.0 2.7e-33 113.7 1.0 2.2 1 0 0 1 1 1 1 C-terminal topoisomerase domain Epimerase PF01370.21 KZN92585.1 - 7e-17 61.7 0.0 9.9e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KZN92585.1 - 4.8e-07 29.1 0.0 1.2e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KZN92585.1 - 6.8e-07 29.0 0.0 1.9e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KZN92585.1 - 4.3e-05 22.7 0.0 5.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Ldh_1_N PF00056.23 KZN92585.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain adh_short PF00106.25 KZN92585.1 - 0.019 14.4 0.0 0.041 13.3 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.10 KZN92585.1 - 0.036 14.0 0.0 0.32 10.9 0.0 2.1 2 0 0 2 2 2 0 KR domain AA_permease PF00324.21 KZN92586.1 - 5.9e-111 371.4 40.7 6.9e-111 371.2 40.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KZN92586.1 - 1.5e-26 93.2 44.9 1.9e-26 92.9 44.9 1.0 1 0 0 1 1 1 1 Amino acid permease Adeno_E3B PF03376.14 KZN92586.1 - 0.026 14.7 4.1 0.09 13.0 0.0 2.7 2 0 0 2 2 2 0 Adenovirus E3B protein Peptidase_M24 PF00557.24 KZN92587.1 - 7.1e-22 78.1 0.2 1e-21 77.6 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 KZN92587.1 - 2.1e-18 67.2 0.0 3.3e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M20 PF01546.28 KZN92588.1 - 5e-27 95.0 0.1 7e-27 94.5 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KZN92588.1 - 1.4e-16 60.4 0.0 3.6e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KZN92588.1 - 0.024 14.3 0.8 0.046 13.4 0.8 1.5 1 0 0 1 1 1 0 Peptidase family M28 Fungal_trans_2 PF11951.8 KZN92589.1 - 3.7e-62 210.3 3.7 4.7e-62 210.0 3.7 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldedh PF00171.22 KZN92590.1 - 4.5e-149 496.9 0.0 6.1e-149 496.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cu_amine_oxid PF01179.20 KZN92591.1 - 3.8e-159 530.0 0.0 4.6e-159 529.7 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KZN92591.1 - 1.4e-09 38.0 0.1 3e-09 37.0 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 KZN92591.1 - 7.2e-06 26.3 0.0 0.00074 19.9 0.0 2.4 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Vta1 PF04652.16 KZN92592.1 - 6e-50 169.0 0.5 8.7e-50 168.5 0.2 1.4 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 KZN92592.1 - 1.5e-16 59.8 0.0 3.4e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 Vta1 C-terminal domain Peptidase_C2 PF00648.21 KZN92593.1 - 8.4e-29 100.5 0.0 1.8e-28 99.4 0.0 1.5 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KZN92593.1 - 1e-09 38.8 0.0 1e-06 29.1 0.0 3.5 3 1 0 3 3 3 2 Calpain large subunit, domain III MIT PF04212.18 KZN92593.1 - 0.25 11.4 4.2 0.43 10.7 4.2 1.3 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Mito_carr PF00153.27 KZN92594.1 - 1.8e-54 181.6 0.7 1.7e-19 69.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein adh_short PF00106.25 KZN92595.1 - 1.9e-25 89.5 0.1 2.7e-25 89.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN92595.1 - 1e-24 87.4 0.1 1.2e-24 87.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KZN92595.1 - 1.9e-09 37.7 0.5 4.7e-09 36.4 0.5 1.7 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KZN92595.1 - 2.4e-09 37.4 0.1 6.1e-09 36.0 0.0 1.7 2 0 0 2 2 2 1 KR domain NmrA PF05368.13 KZN92595.1 - 4.3e-06 26.5 0.1 7.1e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 KZN92595.1 - 0.00019 21.7 0.3 0.00058 20.1 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain 3Beta_HSD PF01073.19 KZN92595.1 - 0.0042 16.1 0.0 0.0062 15.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KZN92595.1 - 0.087 12.2 0.0 0.3 10.4 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase PseudoU_synth_2 PF00849.22 KZN92595.1 - 0.095 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA pseudouridylate synthase Zn_clus PF00172.18 KZN92596.1 - 5.9e-05 23.1 7.4 0.0001 22.3 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Allexi_40kDa PF05549.11 KZN92596.1 - 0.02 14.4 1.6 2.2 7.7 0.1 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein zf-PHD-like PF15446.6 KZN92596.1 - 0.31 10.6 4.7 0.63 9.6 4.7 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain HR1 PF02185.16 KZN92596.1 - 1.5 9.0 4.4 7.8 6.7 0.2 3.1 3 0 0 3 3 3 0 Hr1 repeat Thioredoxin PF00085.20 KZN92597.1 - 2.7e-07 30.5 0.0 0.0039 17.2 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 KZN92597.1 - 0.26 11.8 4.3 0.66 10.5 0.1 2.7 2 1 1 3 3 3 0 Thioredoxin-like domain LCE6A PF15858.5 KZN92597.1 - 8.5 7.2 6.6 2.7 8.8 1.4 2.3 2 0 0 2 2 2 0 Late cornified envelope protein 6A family GNAT_acetyltr_2 PF13718.6 KZN92598.1 - 2.1e-97 325.0 0.0 4e-97 324.1 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KZN92598.1 - 6.2e-83 278.1 0.3 1.1e-82 277.2 0.3 1.4 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KZN92598.1 - 1.7e-65 220.1 0.0 6.5e-65 218.3 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 KZN92598.1 - 4.5e-35 119.5 0.0 1.2e-34 118.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 KZN92598.1 - 0.00077 19.2 0.0 0.033 13.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Acetyltransf_1 PF00583.25 KZN92598.1 - 0.0093 16.2 0.0 0.037 14.3 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family AAA_19 PF13245.6 KZN92598.1 - 0.011 16.0 0.0 0.035 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KZN92598.1 - 0.031 14.5 0.1 0.89 9.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain GHMP_kinases_N PF00288.26 KZN92598.1 - 0.1 12.8 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 GHMP kinases N terminal domain PAC3 PF10178.9 KZN92598.1 - 0.13 12.4 0.0 2.9 8.1 0.0 2.9 2 1 1 3 3 3 0 Proteasome assembly chaperone 3 Acetyltransf_7 PF13508.7 KZN92598.1 - 0.18 12.3 0.0 0.59 10.6 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_transf_90 PF05686.12 KZN92599.1 - 2.4e-11 43.2 0.2 0.002 17.1 0.0 3.8 3 1 0 3 3 3 3 Glycosyl transferase family 90 Glyco_hydro_16 PF00722.21 KZN92600.1 - 2.1e-09 37.1 0.0 4.5e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Vps8 PF12816.7 KZN92601.1 - 2.4e-64 216.5 0.0 4.5e-64 215.6 0.0 1.5 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 KZN92601.1 - 1e-06 28.7 0.0 0.03 14.2 0.0 3.0 2 0 0 2 2 2 2 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 KZN92601.1 - 0.004 17.2 0.4 0.004 17.2 0.4 2.7 3 0 0 3 3 3 1 Zinc-finger Pox_D3 PF04580.13 KZN92601.1 - 0.006 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Chordopoxvirinae D3 protein Syntaxin-18_N PF10496.9 KZN92601.1 - 0.088 13.1 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus zf-RING_11 PF17123.5 KZN92601.1 - 0.15 11.8 0.2 0.5 10.2 0.2 1.9 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 KZN92601.1 - 0.39 10.6 2.1 0.47 10.4 0.0 2.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KZN92601.1 - 1.3 9.4 3.8 2.1 8.7 1.2 2.7 2 1 0 2 2 2 0 RING-H2 zinc finger domain Transferase PF02458.15 KZN92602.1 - 0.0016 17.2 0.0 0.0033 16.1 0.0 1.5 1 0 0 1 1 1 1 Transferase family 2-oxoacid_dh PF00198.23 KZN92602.1 - 0.016 14.7 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Condensation PF00668.20 KZN92602.1 - 0.098 11.3 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Condensation domain Abhydrolase_1 PF00561.20 KZN92604.1 - 0.00022 21.0 0.0 0.00045 19.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KZN92604.1 - 0.0016 17.8 0.4 0.0059 15.9 0.1 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF1749 PF08538.10 KZN92604.1 - 0.014 14.5 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Peptidase_S9 PF00326.21 KZN92604.1 - 0.018 14.5 0.1 0.035 13.6 0.1 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KZN92604.1 - 0.024 15.2 0.0 0.04 14.5 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF4249 PF14054.6 KZN92604.1 - 0.036 13.7 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4249) Pro_CA PF00484.19 KZN92604.1 - 0.086 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Carbonic anhydrase Abhydrolase_5 PF12695.7 KZN92604.1 - 0.12 12.1 0.0 0.56 10.0 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family FAA_hydrolase PF01557.18 KZN92605.1 - 2.7e-59 200.5 0.0 3.6e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Glyoxalase PF00903.25 KZN92606.1 - 7.2e-13 48.9 4.8 1.1e-09 38.6 2.2 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KZN92606.1 - 0.0026 18.0 0.2 0.11 12.8 0.1 2.7 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Fungal_trans PF04082.18 KZN92607.1 - 2.3e-05 23.5 0.0 4.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 KZN92608.1 - 1.1e-64 218.9 0.0 1.4e-64 218.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Peptidase_S9 PF00326.21 KZN92610.1 - 2.5e-53 180.7 0.0 3.8e-53 180.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 KZN92610.1 - 8.8e-05 22.3 1.7 0.0024 17.7 0.1 3.2 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat COesterase PF00135.28 KZN92610.1 - 0.00038 19.5 0.1 0.0006 18.8 0.1 1.2 1 0 0 1 1 1 1 Carboxylesterase family DPPIV_N PF00930.21 KZN92610.1 - 0.029 13.1 0.0 0.089 11.5 0.0 1.9 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region CD36 PF01130.21 KZN92610.1 - 0.066 11.7 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 CD36 family DNA_ligase_A_M PF01068.21 KZN92611.1 - 8.2e-58 195.4 0.4 8.2e-56 188.9 0.4 2.2 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KZN92611.1 - 5e-45 153.9 0.0 9.5e-45 153.0 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KZN92611.1 - 1.6e-26 92.8 0.0 7.3e-26 90.7 0.0 2.3 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KZN92611.1 - 1.6e-05 25.2 0.1 2.6e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 RNA ligase Nucleoporin_FG PF13634.6 KZN92611.1 - 0.11 13.4 7.2 0.26 12.1 7.2 1.6 1 0 0 1 1 1 0 Nucleoporin FG repeat region eIF-5_eIF-2B PF01873.17 KZN92613.1 - 2.9e-39 133.6 0.0 6.2e-39 132.5 0.0 1.6 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KZN92613.1 - 1.8e-21 76.1 0.1 4.9e-21 74.7 0.1 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon HK PF02110.15 KZN92614.1 - 1.6e-73 247.2 0.1 3e-73 246.2 0.1 1.5 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 KZN92614.1 - 2.5e-59 199.6 1.3 3.9e-59 199.0 1.3 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase Carb_kinase PF01256.17 KZN92614.1 - 0.00037 20.0 0.1 0.00096 18.7 0.1 1.6 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 KZN92614.1 - 0.027 13.8 1.0 0.14 11.5 0.0 2.6 3 1 0 3 3 3 0 Phosphomethylpyrimidine kinase PCP_red PF08369.10 KZN92614.1 - 0.091 13.0 0.1 0.26 11.5 0.1 1.8 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit Isochorismatase PF00857.20 KZN92615.1 - 1.6e-28 100.1 0.0 2e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Med22 PF06179.12 KZN92618.1 - 2.8e-17 62.8 0.2 4.8e-17 62.1 0.2 1.3 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Arg_decarbox_C PF17944.1 KZN92618.1 - 0.14 12.8 0.0 0.31 11.6 0.0 1.6 1 0 0 1 1 1 0 Arginine decarboxylase C-terminal helical extension DHFR_1 PF00186.19 KZN92619.1 - 1.4e-19 70.4 0.0 5.1e-13 49.0 0.0 2.5 2 1 0 2 2 2 2 Dihydrofolate reductase Voltage_CLC PF00654.20 KZN92620.1 - 1.1e-88 297.8 25.2 3.1e-88 296.4 20.4 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel PqiA PF04403.13 KZN92620.1 - 0.0028 17.5 2.6 0.0073 16.1 0.5 2.6 2 1 1 3 3 3 1 Paraquat-inducible protein A TAT_signal PF10518.9 KZN92620.1 - 5.7 6.9 7.0 1 9.3 1.2 2.7 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Lipase_GDSL_2 PF13472.6 KZN92621.1 - 4.4e-25 89.1 0.0 1.6e-24 87.3 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KZN92621.1 - 5.5e-17 62.4 0.0 7e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Cwf_Cwc_15 PF04889.12 KZN92622.1 - 2.4e-82 276.4 13.7 2.9e-82 276.1 13.7 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF3752 PF12572.8 KZN92622.1 - 0.23 12.0 14.8 0.35 11.4 14.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) PA26 PF04636.13 KZN92622.1 - 1.9 7.3 3.8 2.4 7.0 3.8 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RNase_PH PF01138.21 KZN92623.1 - 1.5e-17 64.3 0.0 2.3e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KZN92623.1 - 6e-07 29.4 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 PhoLip_ATPase_C PF16212.5 KZN92624.1 - 1.5e-80 270.6 18.9 1.5e-80 270.6 18.9 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KZN92624.1 - 5.1e-26 90.1 10.4 1.7e-25 88.5 10.4 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KZN92624.1 - 1.1e-11 45.4 1.4 1.1e-06 29.1 0.2 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KZN92624.1 - 4.7e-11 42.6 0.0 1.8e-10 40.8 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KZN92624.1 - 9.8e-06 25.2 0.0 3e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KZN92624.1 - 0.0056 16.4 0.3 0.019 14.7 0.2 1.9 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase DNA_pol_lambd_f PF10391.9 KZN92625.1 - 2.6e-21 75.2 0.7 5.8e-21 74.1 0.7 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.6 KZN92625.1 - 2.6e-21 75.5 0.5 1.4e-20 73.2 0.4 2.3 3 0 0 3 3 3 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 KZN92625.1 - 5e-15 55.7 0.3 1.7e-14 54.0 0.3 1.9 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 KZN92625.1 - 3.2e-09 37.0 0.0 1.4e-08 35.0 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.6 KZN92625.1 - 9.7e-05 22.9 0.0 0.0011 19.5 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain THRAP3_BCLAF1 PF15440.6 KZN92625.1 - 0.017 14.2 4.8 0.67 8.9 0.0 2.1 2 0 0 2 2 2 0 THRAP3/BCLAF1 family NTP_transf_2 PF01909.23 KZN92625.1 - 0.054 13.8 0.2 0.15 12.3 0.1 1.9 2 0 0 2 2 2 0 Nucleotidyltransferase domain NicO PF03824.16 KZN92627.1 - 4e-62 210.1 16.5 6.2e-59 199.7 6.4 2.5 2 1 0 2 2 2 2 High-affinity nickel-transport protein DctQ PF04290.12 KZN92627.1 - 0.02 14.8 1.7 0.02 14.8 1.7 3.3 4 1 0 5 5 5 0 Tripartite ATP-independent periplasmic transporters, DctQ component ATP-synt_B PF00430.18 KZN92627.1 - 0.16 12.0 0.2 28 4.8 0.0 2.6 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Peptidase_M14 PF00246.24 KZN92629.1 - 5.7e-79 265.9 0.0 7.1e-79 265.6 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Sec7 PF01369.20 KZN92630.1 - 6.3e-29 100.9 0.1 1.2e-28 100.0 0.1 1.4 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 KZN92630.1 - 5.5e-05 23.6 0.2 0.00016 22.1 0.2 1.9 1 1 0 1 1 1 1 PH domain PH_9 PF15410.6 KZN92630.1 - 9.3e-05 22.8 0.3 0.00022 21.6 0.3 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain p450 PF00067.22 KZN92630.1 - 0.014 14.1 0.2 0.024 13.4 0.2 1.2 1 0 0 1 1 1 0 Cytochrome P450 zf-RING_UBOX PF13445.6 KZN92631.1 - 2.2e-06 27.6 9.4 0.00013 21.9 3.9 2.8 2 1 0 2 2 2 2 RING-type zinc-finger zf-NOSIP PF15906.5 KZN92631.1 - 6.9e-05 22.9 0.1 0.00021 21.4 0.0 1.9 2 0 0 2 2 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_5 PF14634.6 KZN92631.1 - 0.00022 21.1 6.3 0.00022 21.1 6.3 2.6 2 2 0 2 2 2 1 zinc-RING finger domain Rtf2 PF04641.12 KZN92631.1 - 0.00076 18.9 14.0 0.0015 17.9 1.4 3.1 2 1 1 3 3 3 2 Rtf2 RING-finger zf-RING_2 PF13639.6 KZN92631.1 - 0.001 19.4 12.9 0.0081 16.5 4.0 2.8 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.6 KZN92631.1 - 0.0011 18.7 11.6 0.0017 18.1 4.7 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KZN92631.1 - 0.0014 18.4 13.4 0.0066 16.3 3.1 3.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KZN92631.1 - 0.0041 17.0 5.1 0.0041 17.0 5.1 3.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KZN92631.1 - 0.05 13.7 13.7 0.041 14.0 4.9 3.4 2 2 1 3 3 3 0 FYVE zinc finger zf-C3HC4_5 PF17121.5 KZN92631.1 - 0.16 11.9 2.7 0.47 10.4 2.7 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4407 PF14362.6 KZN92631.1 - 0.53 9.6 6.1 0.6 9.4 2.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) IBR PF01485.21 KZN92631.1 - 5.3 7.4 9.4 4.5 7.6 0.8 3.1 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain Prok-RING_4 PF14447.6 KZN92631.1 - 6.5 6.7 19.7 4 7.4 8.7 3.7 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KZN92631.1 - 9.9 6.4 13.9 0.85 9.8 2.7 3.3 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING Endonuclease_NS PF01223.23 KZN92632.1 - 8.1e-65 218.8 0.0 1.1e-64 218.3 0.0 1.2 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Zip PF02535.22 KZN92633.1 - 1.2e-24 87.2 8.5 2.4e-18 66.5 5.7 2.2 2 0 0 2 2 2 2 ZIP Zinc transporter PAD_N PF08526.10 KZN92633.1 - 0.1 13.0 0.8 0.21 12.0 0.3 1.7 2 0 0 2 2 2 0 Protein-arginine deiminase (PAD) N-terminal domain DUF2095 PF09868.9 KZN92634.1 - 0.1 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) AAA_16 PF13191.6 KZN92635.1 - 2.7e-06 27.9 0.3 3.7e-05 24.2 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KZN92635.1 - 9.8e-05 22.6 0.0 0.00093 19.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 KZN92635.1 - 0.00023 21.1 0.3 0.0011 18.9 0.0 2.3 3 0 0 3 3 3 1 NACHT domain NB-ARC PF00931.22 KZN92635.1 - 0.00066 18.9 0.0 0.0023 17.1 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain TPR_12 PF13424.6 KZN92635.1 - 0.00066 19.9 15.0 1 9.7 0.3 6.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 KZN92635.1 - 0.011 15.7 3.1 1.1 9.5 0.1 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Shikimate_DH PF01488.20 KZN92635.1 - 0.014 15.5 0.1 0.05 13.7 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase AAA_19 PF13245.6 KZN92635.1 - 0.015 15.6 0.0 0.064 13.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain TPR_19 PF14559.6 KZN92635.1 - 0.086 13.4 1.9 12 6.5 0.1 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Ribosomal_S30 PF04758.14 KZN92636.1 - 4.3e-28 97.3 6.8 4.7e-28 97.2 6.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 DUF2040 PF09745.9 KZN92637.1 - 1.5e-37 128.4 18.8 1.5e-37 128.4 18.8 3.5 4 1 0 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) Sedlin_N PF04628.13 KZN92638.1 - 1.7e-42 144.7 0.0 2.1e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KZN92638.1 - 0.0011 18.9 0.0 0.0051 16.7 0.0 1.9 2 0 0 2 2 2 1 Sybindin-like family Isochorismatase PF00857.20 KZN92639.1 - 3.2e-43 147.9 0.0 1.2e-42 146.0 0.0 1.8 2 0 0 2 2 2 1 Isochorismatase family FAR1 PF03101.15 KZN92639.1 - 1.5e-05 25.6 0.0 2.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.11 KZN92639.1 - 0.016 15.6 0.0 0.028 14.8 0.0 1.3 1 0 0 1 1 1 0 Transcription factor AFT Catalase_C PF18011.1 KZN92639.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain found in long catalases NUDE_C PF04880.13 KZN92640.1 - 3.1e-65 220.0 8.8 3.1e-65 220.0 8.8 5.0 2 2 2 6 6 3 1 NUDE protein, C-terminal conserved region ZapB PF06005.12 KZN92640.1 - 0.023 15.1 8.8 0.023 15.1 8.8 4.7 2 1 3 5 5 5 0 Cell division protein ZapB PSII_Pbs27 PF13326.6 KZN92640.1 - 0.038 14.3 4.2 0.084 13.2 4.2 1.6 1 0 0 1 1 1 0 Photosystem II Pbs27 DUF4201 PF13870.6 KZN92640.1 - 0.31 10.7 24.2 0.027 14.2 2.4 3.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) ERM PF00769.19 KZN92640.1 - 0.62 9.8 30.9 1.2 8.8 30.9 1.5 1 0 0 1 1 1 0 Ezrin/radixin/moesin family GAS PF13851.6 KZN92640.1 - 0.67 9.3 28.4 12 5.2 21.5 3.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 KZN92640.1 - 1.1 8.7 29.6 3 7.3 12.5 2.6 1 1 1 2 2 2 0 Intermediate filament protein DUF745 PF05335.13 KZN92640.1 - 1.7 8.4 8.9 3.2 7.5 8.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Tho2 PF11262.8 KZN92640.1 - 2.1 7.4 19.8 0.066 12.4 3.4 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 TPR_MLP1_2 PF07926.12 KZN92640.1 - 2.6 8.1 32.0 3.5 7.7 7.6 3.9 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein DUF812 PF05667.11 KZN92640.1 - 3 6.6 26.1 5.1 5.9 26.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) APG6_N PF17675.1 KZN92640.1 - 3.8 8.0 38.1 0.22 12.1 9.3 3.3 1 1 2 3 3 3 0 Apg6 coiled-coil region Chibby PF14645.6 KZN92640.1 - 5.2 7.5 14.3 3.5 8.1 6.8 3.0 1 1 1 2 2 2 0 Chibby family PRKG1_interact PF15898.5 KZN92640.1 - 5.9 7.8 27.7 60 4.6 19.2 3.2 2 1 1 3 3 2 0 cGMP-dependent protein kinase interacting domain Fez1 PF06818.15 KZN92640.1 - 6.3 7.2 27.9 5 7.5 12.4 2.8 2 1 1 3 3 3 0 Fez1 ADIP PF11559.8 KZN92640.1 - 8.9 6.4 30.5 1.2 9.2 4.2 3.4 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding ACC_central PF08326.12 KZN92641.1 - 5.3e-280 930.8 0.0 6.8e-280 930.5 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KZN92641.1 - 7.3e-188 625.2 0.0 1.5e-187 624.2 0.0 1.5 2 0 0 2 2 2 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KZN92641.1 - 5.1e-52 176.4 0.0 1e-51 175.4 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KZN92641.1 - 4.4e-28 98.0 0.1 9.6e-28 96.9 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KZN92641.1 - 8.8e-24 83.7 0.0 9.8e-20 70.7 0.0 3.5 4 0 0 4 4 4 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KZN92641.1 - 4.4e-17 61.7 0.1 1.2e-16 60.3 0.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 KZN92641.1 - 0.00017 21.7 0.0 0.00067 19.7 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KZN92641.1 - 0.0002 20.9 0.0 0.00057 19.5 0.0 1.7 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus GxGYxYP_N PF16216.5 KZN92641.1 - 0.034 14.3 0.0 0.07 13.3 0.0 1.4 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal ATPgrasp_Ter PF15632.6 KZN92641.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon MFS_1 PF07690.16 KZN92643.1 - 3e-30 105.4 62.1 1.9e-29 102.7 58.2 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily F-box-like PF12937.7 KZN92645.1 - 5.1e-07 29.5 0.2 2e-06 27.6 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KZN92645.1 - 0.079 12.9 0.1 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 F-box domain NOA36 PF06524.12 KZN92645.1 - 4.9 6.4 7.8 9.1 5.5 7.8 1.4 1 0 0 1 1 1 0 NOA36 protein DUF3669 PF12417.8 KZN92646.1 - 2.9e-15 56.2 0.4 8.3e-15 54.7 0.4 1.8 1 0 0 1 1 1 1 Zinc finger protein HeLo PF14479.6 KZN92647.1 - 0.00029 20.7 0.4 0.02 14.7 0.4 2.4 1 1 0 1 1 1 1 Prion-inhibition and propagation Peptidase_S64 PF08192.11 KZN92647.1 - 0.054 12.0 0.0 0.16 10.5 0.0 1.6 2 0 0 2 2 2 0 Peptidase family S64 RINGv PF12906.7 KZN92648.1 - 2.8e-16 59.4 9.4 4.8e-16 58.6 9.4 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KZN92648.1 - 0.046 14.1 9.8 0.081 13.3 9.8 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 KZN92648.1 - 0.7 9.7 6.2 1.2 9.0 6.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KZN92648.1 - 0.98 9.6 6.1 1.9 8.7 6.1 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 KZN92648.1 - 2.7 7.9 5.6 6 6.8 5.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4055 PF13264.6 KZN92649.1 - 0.037 14.2 5.4 0.2 11.8 5.4 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) TMEM208_SND2 PF05620.11 KZN92650.1 - 2.2e-56 190.2 0.0 2.5e-56 190.1 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 YwiC PF14256.6 KZN92650.1 - 0.03 14.6 4.8 0.18 12.1 0.1 2.1 2 0 0 2 2 2 0 YwiC-like protein TPR_1 PF00515.28 KZN92651.1 - 2e-45 150.8 17.5 4.8e-08 32.5 0.0 9.7 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 KZN92651.1 - 3.6e-41 136.0 18.8 1.9e-05 24.4 0.3 10.2 10 0 0 10 10 10 7 Tetratricopeptide repeat ANAPC3 PF12895.7 KZN92651.1 - 2.8e-30 104.4 18.7 2.4e-22 79.0 1.3 4.5 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KZN92651.1 - 2e-27 93.0 8.1 0.0022 18.0 0.0 9.5 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 KZN92651.1 - 4.5e-22 78.3 16.4 1.4e-08 35.1 0.2 8.3 8 1 1 9 9 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 KZN92651.1 - 1.9e-21 75.4 8.6 4e-05 23.2 2.5 9.0 8 2 1 9 9 9 5 TPR repeat TPR_16 PF13432.6 KZN92651.1 - 2.5e-19 69.6 22.6 0.00078 20.0 0.2 8.1 7 1 1 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.6 KZN92651.1 - 3.1e-19 68.0 7.8 0.057 14.3 0.0 9.2 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 KZN92651.1 - 5.8e-16 58.6 19.2 0.02 15.2 0.6 7.9 5 2 3 8 8 8 6 Tetratricopeptide repeat TPR_7 PF13176.6 KZN92651.1 - 1.1e-13 50.1 1.8 0.0015 18.4 0.0 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 KZN92651.1 - 6.4e-12 45.0 11.6 0.064 13.7 0.0 7.9 9 0 0 9 9 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 KZN92651.1 - 2.5e-09 37.2 3.6 2.8 8.8 0.1 8.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 KZN92651.1 - 1.5e-05 24.7 0.1 8 6.5 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 KZN92651.1 - 0.00011 22.3 3.7 6.1 7.1 0.0 5.7 4 1 2 7 7 6 2 Tetratricopeptide repeat TPR_21 PF09976.9 KZN92651.1 - 0.0084 15.8 8.8 0.14 11.8 1.0 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat-like domain Sel1 PF08238.12 KZN92651.1 - 0.096 13.4 1.1 23 5.8 0.0 5.1 6 0 0 6 6 5 0 Sel1 repeat ChAPs PF09295.10 KZN92651.1 - 0.22 10.5 0.7 14 4.6 0.2 2.3 1 1 2 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) MIT PF04212.18 KZN92651.1 - 9.4 6.4 6.8 13 5.9 0.5 4.2 5 1 1 6 6 6 0 MIT (microtubule interacting and transport) domain Acyltransferase PF01553.21 KZN92652.1 - 2.5e-31 108.1 0.0 4.1e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase ACPS PF01648.20 KZN92653.1 - 6.7e-11 42.3 0.0 1.6e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily SNO PF01174.19 KZN92654.1 - 8.3e-55 185.5 0.0 8e-45 153.0 0.0 2.1 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 KZN92654.1 - 4.4e-09 36.2 0.0 8.7e-08 32.0 0.0 2.1 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 KZN92654.1 - 0.00095 19.0 0.0 0.01 15.6 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 KZN92654.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family Peptidase_S51 PF03575.17 KZN92654.1 - 0.014 15.0 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 GATase_5 PF13507.6 KZN92654.1 - 0.016 14.3 0.0 0.66 9.0 0.0 2.2 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain RRM_1 PF00076.22 KZN92655.1 - 8.9e-16 57.5 0.0 1.3e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF948 PF06103.11 KZN92656.1 - 0.21 11.9 0.5 1.2 9.5 0.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 KZN92656.1 - 0.36 11.2 5.5 0.95 9.8 0.0 3.5 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 kleA_kleC PF17383.2 KZN92656.1 - 0.39 11.1 3.5 4.9 7.6 0.2 3.1 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A Rotamase PF00639.21 KZN92659.1 - 4.4e-23 82.1 0.1 5.8e-23 81.7 0.1 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KZN92659.1 - 3.4e-14 53.4 0.0 4.5e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 KZN92659.1 - 5.4e-10 39.2 1.6 5.4e-10 39.2 1.6 1.8 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 KZN92659.1 - 8e-05 23.5 0.0 0.00013 22.7 0.0 1.5 2 0 0 2 2 2 1 PPIC-type PPIASE domain TFIIS_C PF01096.18 KZN92660.1 - 5e-14 51.9 3.3 5e-14 51.9 3.3 3.4 5 0 0 5 5 5 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KZN92660.1 - 3.8e-11 42.7 1.6 3.8e-11 42.7 1.6 3.9 4 1 0 4 4 4 1 RNA polymerases M/15 Kd subunit Ribosomal_L14 PF00238.19 KZN92661.1 - 8.2e-47 158.3 2.1 9.1e-47 158.1 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e FlgH PF02107.16 KZN92661.1 - 0.027 14.1 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein Phage_antitermQ PF06530.12 KZN92661.1 - 0.052 13.5 0.1 0.079 12.9 0.1 1.4 1 1 0 1 1 1 0 Phage antitermination protein Q DUF4777 PF16007.5 KZN92661.1 - 0.14 12.4 0.1 0.5 10.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) SET PF00856.28 KZN92662.1 - 3.2e-11 43.9 0.0 5.2e-09 36.7 0.0 2.8 2 0 0 2 2 2 2 SET domain FAM76 PF16046.5 KZN92662.1 - 3.9 6.8 14.3 0.8 9.0 0.7 2.5 3 0 0 3 3 3 0 FAM76 protein COesterase PF00135.28 KZN92663.1 - 9.8e-70 235.9 0.0 1.7e-69 235.1 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KZN92663.1 - 0.0001 22.2 0.2 0.0032 17.4 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KZN92663.1 - 0.044 13.2 0.0 0.067 12.7 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family DEAD PF00270.29 KZN92664.1 - 2.1e-30 105.8 0.0 4.1e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KZN92664.1 - 3.5e-19 69.2 0.4 2.6e-18 66.4 0.3 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KZN92664.1 - 5.4e-06 26.5 0.0 9.4e-05 22.5 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PH PF00169.29 KZN92665.1 - 1.1e-07 32.3 0.0 3.2e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 PH domain Anillin PF08174.11 KZN92665.1 - 8.3e-06 26.3 0.0 2.3e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Cell division protein anillin Kelch_3 PF13415.6 KZN92666.1 - 1.4e-32 111.3 6.0 1.5e-06 28.3 0.0 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KZN92666.1 - 2.6e-27 94.6 5.9 5.5e-12 45.5 0.1 5.6 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KZN92666.1 - 1.2e-17 63.5 0.7 0.00023 21.3 0.0 5.9 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.25 KZN92666.1 - 1.2e-12 47.2 1.1 0.0037 16.8 0.0 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 KZN92666.1 - 1.1e-11 44.2 6.8 0.00041 20.2 0.1 6.1 6 1 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 KZN92666.1 - 2.2e-11 43.5 0.8 0.00093 19.1 0.0 5.7 6 0 0 6 6 6 2 Kelch motif ASFV_J13L PF05568.11 KZN92666.1 - 0.053 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein LRR_10 PF18805.1 KZN92666.1 - 0.075 12.7 0.1 8.8 6.1 0.0 2.8 2 0 0 2 2 2 0 Leucine-rich repeat DUF829 PF05705.14 KZN92668.1 - 7.1e-51 173.4 0.1 8.2e-51 173.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Fungal_trans PF04082.18 KZN92669.1 - 1.5e-15 57.0 0.9 1.5e-15 57.0 0.9 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Trimer_CC PF08954.11 KZN92669.1 - 0.16 11.5 1.1 0.88 9.2 0.1 2.4 2 0 0 2 2 2 0 Trimerisation motif DUF1509 PF07420.11 KZN92669.1 - 0.45 9.4 3.8 0.31 10.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1509) Acyl_transf_3 PF01757.22 KZN92670.1 - 2.8e-18 66.1 24.8 9.6e-18 64.3 24.9 1.9 1 1 0 1 1 1 1 Acyltransferase family DUF202 PF02656.15 KZN92674.1 - 2.8e-16 59.7 0.6 2.8e-16 59.7 0.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Fumarate_red_C PF02300.17 KZN92674.1 - 0.0084 16.2 0.9 0.012 15.6 0.9 1.2 1 0 0 1 1 1 1 Fumarate reductase subunit C DUF2818 PF10993.8 KZN92674.1 - 0.07 13.7 0.5 0.14 12.7 0.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2818) GCV_T PF01571.21 KZN92675.1 - 8.1e-74 248.2 0.0 1.2e-73 247.7 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 KZN92675.1 - 7e-46 157.4 0.9 1.1e-45 156.8 0.9 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T_C PF08669.11 KZN92675.1 - 4.4e-20 71.4 0.0 1e-19 70.2 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FAO_M PF16350.5 KZN92675.1 - 2.2e-19 69.5 0.0 4.2e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain Pyr_redox_2 PF07992.14 KZN92675.1 - 3.8e-06 26.3 0.0 0.041 13.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KZN92675.1 - 4.9e-05 23.8 0.0 0.013 16.0 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KZN92675.1 - 0.003 17.8 0.1 0.013 15.8 0.1 2.0 2 0 0 2 2 2 1 TrkA-N domain SoxG PF04268.12 KZN92675.1 - 0.0039 17.4 0.0 0.0098 16.1 0.0 1.7 1 0 0 1 1 1 1 Sarcosine oxidase, gamma subunit family NAD_binding_9 PF13454.6 KZN92675.1 - 0.0084 16.1 0.1 0.6 10.1 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KZN92675.1 - 0.018 15.1 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KZN92675.1 - 0.037 13.3 0.4 0.43 9.8 0.4 2.1 1 1 0 1 1 1 0 FAD binding domain ThiF PF00899.21 KZN92675.1 - 0.049 13.0 0.1 0.085 12.2 0.1 1.3 1 0 0 1 1 1 0 ThiF family NAD_binding_8 PF13450.6 KZN92675.1 - 0.057 13.7 0.0 0.23 11.7 0.0 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain MFS_1 PF07690.16 KZN92677.1 - 7.8e-13 48.1 47.5 3.3e-12 46.0 45.9 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4203 PF13886.6 KZN92677.1 - 0.011 15.4 11.2 0.011 15.4 11.2 3.9 2 2 0 3 3 3 0 Domain of unknown function (DUF4203) Pox_A14 PF05767.12 KZN92677.1 - 0.1 12.8 3.3 0.52 10.5 0.2 3.3 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 p450 PF00067.22 KZN92679.1 - 9.4e-60 202.7 0.0 1.3e-59 202.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Prok-E2_A PF14457.6 KZN92679.1 - 0.056 13.1 0.3 0.1 12.2 0.3 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family A DRAT PF07357.11 KZN92679.1 - 0.092 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) TFIIE_alpha PF02002.17 KZN92680.1 - 1.6e-17 63.3 0.0 3.1e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit DUF3944 PF13099.6 KZN92680.1 - 0.15 12.0 0.3 0.32 10.9 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) PseudoU_synth_1 PF01416.20 KZN92681.1 - 8e-13 48.8 0.0 6.7e-11 42.6 0.0 2.6 2 0 0 2 2 2 1 tRNA pseudouridine synthase YlbE PF14003.6 KZN92681.1 - 0.1 13.0 0.3 0.33 11.4 0.3 1.9 1 0 0 1 1 1 0 YlbE-like protein DUF3517 PF12030.8 KZN92682.1 - 1.6e-87 293.6 0.0 3.1e-87 292.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.29 KZN92682.1 - 6.6e-39 133.9 0.1 1.7e-38 132.6 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KZN92682.1 - 2e-21 76.9 0.1 2.1e-20 73.6 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase ADD_ATRX PF17981.1 KZN92682.1 - 0.14 12.0 0.1 0.45 10.4 0.1 1.8 1 0 0 1 1 1 0 Cysteine Rich ADD domain Hexapep PF00132.24 KZN92683.1 - 7.2e-13 47.7 7.3 7.2e-11 41.4 2.9 3.1 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KZN92683.1 - 4.3e-12 45.6 7.5 5.1e-10 38.9 2.6 3.0 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 KZN92683.1 - 5.3e-11 42.6 0.2 8.4e-11 41.9 0.2 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase ICMT PF04140.14 KZN92684.1 - 7.8e-27 93.5 1.1 1.4e-26 92.7 1.1 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KZN92684.1 - 1.5e-10 41.4 3.3 1.5e-10 41.4 3.3 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 KZN92684.1 - 1.5e-07 31.2 1.1 2.1e-07 30.7 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Tmemb_170 PF10190.9 KZN92686.1 - 1e-23 83.7 12.1 1.2e-23 83.5 12.1 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 WD40 PF00400.32 KZN92687.1 - 1.8e-30 104.5 29.0 2.2e-06 28.3 2.4 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN92687.1 - 3.7e-17 62.4 0.3 0.00031 21.0 0.0 5.6 2 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KZN92687.1 - 0.0024 17.8 0.1 0.96 9.3 0.1 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KZN92687.1 - 0.084 11.2 0.0 0.26 9.6 0.0 1.6 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Bacteroid_pep PF14406.6 KZN92687.1 - 0.18 12.2 0.0 0.61 10.5 0.0 2.0 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Bacteroidetes MBOAT PF03062.19 KZN92688.1 - 1.2e-25 90.7 14.0 1.9e-25 90.0 14.0 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KZN92688.1 - 0.024 14.9 2.8 0.07 13.4 2.8 1.8 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family MAPEG PF01124.18 KZN92689.1 - 9.7e-26 90.2 1.4 1.1e-25 90.0 1.4 1.0 1 0 0 1 1 1 1 MAPEG family OMPdecase PF00215.24 KZN92690.1 - 1.1e-77 260.6 0.0 1.3e-77 260.4 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family MFS_1 PF07690.16 KZN92691.1 - 9.2e-39 133.3 22.2 1.9e-38 132.3 20.3 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Saf_2TM PF18303.1 KZN92691.1 - 0.16 11.6 0.3 4.9 6.7 0.0 2.8 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain S4 PF01479.25 KZN92693.1 - 4.3e-14 51.9 0.0 7.6e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 KZN92693.1 - 2.9e-11 44.1 2.5 4.1e-11 43.6 2.4 1.4 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Occludin_ELL PF07303.13 KZN92693.1 - 0.043 14.6 0.3 0.13 13.0 0.1 1.9 1 1 1 2 2 2 0 Occludin homology domain Clr5 PF14420.6 KZN92694.1 - 9.9e-11 41.7 0.2 4.9e-10 39.5 0.1 2.1 2 0 0 2 2 2 1 Clr5 domain Sigma54_DBD PF04552.13 KZN92694.1 - 7.1e-05 22.6 0.6 0.0058 16.3 0.0 2.3 1 1 1 2 2 2 1 Sigma-54, DNA binding domain rve PF00665.26 KZN92694.1 - 0.00014 22.1 0.5 0.69 10.1 0.1 2.4 2 0 0 2 2 2 2 Integrase core domain HTH_12 PF08461.10 KZN92694.1 - 0.045 13.7 0.2 2.4 8.2 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain HTH_Tnp_Tc3_2 PF01498.18 KZN92694.1 - 0.048 13.9 0.4 11 6.3 0.0 2.8 2 0 0 2 2 2 0 Transposase HTH_21 PF13276.6 KZN92694.1 - 0.11 12.7 1.2 0.42 10.8 0.1 2.5 2 0 0 2 2 2 0 HTH-like domain ketoacyl-synt PF00109.26 KZN92695.1 - 1.1e-67 228.2 0.0 1e-66 225.1 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KZN92695.1 - 3.2e-62 210.4 0.0 5.7e-62 209.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KZN92695.1 - 2.6e-61 206.7 0.3 6.1e-61 205.5 0.3 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KZN92695.1 - 5e-45 154.4 0.0 9.3e-45 153.5 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KZN92695.1 - 9.9e-33 112.7 0.0 2.1e-32 111.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KZN92695.1 - 1.1e-18 67.7 0.0 6.5e-18 65.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KZN92695.1 - 8.6e-15 55.2 0.0 4.3e-11 43.2 0.0 2.7 2 0 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 KZN92695.1 - 2.8e-11 43.5 0.0 8.1e-11 42.0 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 KZN92695.1 - 3.2e-11 43.3 0.0 6.9e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN92695.1 - 1.2e-10 41.9 0.0 7.4e-10 39.4 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain adh_short PF00106.25 KZN92695.1 - 5.7e-10 39.0 0.1 1.6e-09 37.5 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_31 PF13847.6 KZN92695.1 - 3e-09 36.8 0.0 9.8e-09 35.2 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN92695.1 - 3.6e-08 33.9 0.0 1.1e-07 32.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KZN92695.1 - 6e-08 33.8 0.0 5.7e-07 30.6 0.0 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 KZN92695.1 - 1.2e-06 28.8 0.1 3e-06 27.5 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site NodS PF05401.11 KZN92695.1 - 1e-05 25.2 0.0 2.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Nodulation protein S (NodS) Thiolase_N PF00108.23 KZN92695.1 - 0.00027 20.4 0.0 0.00068 19.1 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_28 PF02636.17 KZN92695.1 - 0.00036 20.2 0.0 0.044 13.4 0.0 2.6 3 0 0 3 3 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.18 KZN92695.1 - 0.0011 18.4 0.0 0.0026 17.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ADH_N PF08240.12 KZN92695.1 - 0.025 14.5 0.1 0.081 12.8 0.1 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Methyltransf_16 PF10294.9 KZN92695.1 - 0.058 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase DnaJ PF00226.31 KZN92696.1 - 1.7e-24 85.7 1.4 3e-24 84.9 1.4 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 KZN92696.1 - 9e-24 84.2 0.0 1.3e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KZN92696.1 - 1.9e-15 57.0 15.5 3.2e-15 56.2 15.5 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KZN92696.1 - 1.3e-06 28.3 6.7 0.01 15.8 1.0 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KZN92696.1 - 0.017 15.2 7.1 1.1 9.3 1.5 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 KZN92696.1 - 0.13 11.9 8.8 0.17 11.6 0.8 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Lar_restr_allev PF14354.6 KZN92696.1 - 0.23 11.8 9.4 2.5 8.5 1.5 3.0 1 1 2 3 3 3 0 Restriction alleviation protein Lar Cytochrom_c3_2 PF14537.6 KZN92696.1 - 0.3 11.6 9.4 0.75 10.3 9.4 1.7 1 1 0 1 1 1 0 Cytochrome c3 Cytochrome_C7 PF14522.6 KZN92696.1 - 4.9 7.2 11.8 19 5.4 11.8 2.0 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c DUF4449 PF14613.6 KZN92697.1 - 0.00017 21.8 9.5 0.00024 21.3 1.7 3.8 2 2 1 3 3 3 1 Protein of unknown function (DUF4449) Tricorn_C1 PF14684.6 KZN92697.1 - 0.00057 19.9 0.4 0.014 15.4 0.2 3.1 3 0 0 3 3 3 1 Tricorn protease C1 domain PKHD_C PF18331.1 KZN92697.1 - 0.032 14.3 0.3 0.74 9.9 0.2 3.0 3 0 0 3 3 3 0 PKHD-type hydroxylase C-terminal domain SbsC_C PF18058.1 KZN92697.1 - 0.067 13.4 0.5 0.067 13.4 0.5 2.5 4 0 0 4 4 4 0 SbsC C-terminal domain NPR3 PF03666.13 KZN92697.1 - 0.09 11.6 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF5536 PF17688.1 KZN92697.1 - 1.4 8.8 5.4 13 5.6 2.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5536) Malic_M PF03949.15 KZN92698.1 - 4e-90 301.6 0.0 6e-90 301.0 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KZN92698.1 - 2.7e-63 213.0 0.0 8e-63 211.5 0.0 1.7 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain Oxidored_FMN PF00724.20 KZN92699.1 - 1.5e-43 149.4 0.0 1.9e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family HLH PF00010.26 KZN92700.1 - 0.0032 17.4 0.1 0.0077 16.2 0.1 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Csm1_N PF18504.1 KZN92700.1 - 0.03 14.7 0.3 0.053 13.9 0.3 1.4 1 0 0 1 1 1 0 Csm1 N-terminal domain Fungal_trans PF04082.18 KZN92701.1 - 8.6e-28 97.1 0.0 2.2e-27 95.8 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN92701.1 - 3.2e-07 30.4 7.2 7.7e-07 29.1 7.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN92702.1 - 1.5e-30 106.1 1.9 2.7e-30 105.3 1.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN92702.1 - 2.1e-08 34.1 13.3 3.4e-08 33.5 13.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KZN92703.1 - 3.7e-48 164.3 46.2 2e-45 155.3 48.8 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KZN92703.1 - 1.6e-14 53.3 17.1 1.6e-14 53.3 17.1 1.9 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KZN92703.1 - 2.4e-10 39.9 13.3 2.4e-10 39.9 13.3 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter DBD_Tnp_Mut PF03108.15 KZN92704.1 - 2.3e-08 33.9 1.3 3.9e-08 33.2 1.3 1.3 1 0 0 1 1 1 1 MuDR family transposase THOC7 PF05615.13 KZN92705.1 - 6.9e-43 146.1 8.1 6.9e-43 146.1 8.1 1.9 1 1 1 2 2 2 1 Tho complex subunit 7 Mod_r PF07200.13 KZN92705.1 - 0.016 15.3 9.6 0.029 14.5 9.6 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Peroxin-13_N PF04088.13 KZN92705.1 - 0.15 12.4 0.2 0.36 11.1 0.2 1.6 1 1 0 1 1 1 0 Peroxin 13, N-terminal region DUF4600 PF15372.6 KZN92705.1 - 0.27 11.7 8.6 0.59 10.6 8.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) FUSC PF04632.12 KZN92705.1 - 2.8 6.4 8.1 3.6 6.0 8.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Lipoprotein_20 PF13942.6 KZN92705.1 - 5.4 6.9 12.6 0.94 9.4 7.3 2.0 1 1 1 2 2 2 0 YfhG lipoprotein CENP-H PF05837.12 KZN92705.1 - 7.2 7.1 10.7 2.6 8.5 2.6 2.4 1 1 2 3 3 3 0 Centromere protein H (CENP-H) TBCA PF02970.16 KZN92706.1 - 1e-23 83.5 8.2 1e-23 83.5 8.2 1.3 1 1 0 1 1 1 1 Tubulin binding cofactor A DUF1910 PF08928.10 KZN92706.1 - 0.18 11.8 4.2 0.23 11.5 3.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1910) Prominin PF05478.11 KZN92706.1 - 0.21 9.5 4.7 0.24 9.3 4.7 1.0 1 0 0 1 1 1 0 Prominin zf-C4H2 PF10146.9 KZN92706.1 - 2.1 8.6 8.6 2.7 8.2 8.6 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein CENP-Q PF13094.6 KZN92706.1 - 3.1 8.0 11.1 16 5.7 11.1 1.9 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Elongin_A PF06881.11 KZN92707.1 - 4.6e-26 91.4 0.1 7.9e-26 90.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A ubiquitin PF00240.23 KZN92708.1 - 1.9e-25 88.4 0.0 2.2e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KZN92708.1 - 3.3e-14 52.5 0.0 3.6e-14 52.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KZN92708.1 - 0.00052 20.4 0.0 0.0019 18.6 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KZN92708.1 - 0.015 15.2 0.0 0.019 14.9 0.0 1.1 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain LigT_PEase PF02834.16 KZN92709.1 - 0.013 15.7 0.1 7.8 6.8 0.0 2.5 2 0 0 2 2 2 0 LigT like Phosphoesterase Ribosomal_L44 PF00935.19 KZN92710.1 - 4.1e-29 100.9 6.2 5.7e-29 100.4 6.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Herpes_gI PF01688.17 KZN92710.1 - 0.13 12.2 0.1 0.13 12.2 0.1 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I Sugar_tr PF00083.24 KZN92711.1 - 2e-83 280.8 30.2 2.3e-83 280.6 30.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN92711.1 - 5.9e-28 97.8 27.8 2.6e-27 95.7 25.5 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily PalH PF08733.10 KZN92711.1 - 1.4 7.8 7.7 2.8 6.9 7.7 1.5 1 0 0 1 1 1 0 PalH/RIM21 Fungal_trans PF04082.18 KZN92712.1 - 2.4e-11 43.2 0.2 4.9e-11 42.2 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN92712.1 - 1.1e-07 31.8 6.2 2e-07 31.0 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4449 PF14613.6 KZN92712.1 - 0.008 16.3 1.0 2.1 8.4 0.3 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF4449) Med3 PF11593.8 KZN92712.1 - 0.019 14.2 16.0 0.038 13.2 13.9 2.0 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal REC114-like PF15165.6 KZN92712.1 - 0.056 13.2 4.6 0.089 12.6 4.6 1.2 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like Dickkopf_N PF04706.12 KZN92712.1 - 1.6 9.3 6.3 5.7 7.5 6.3 2.0 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Acetyltransf_1 PF00583.25 KZN92713.1 - 1.3e-05 25.4 0.0 1.9e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KZN92713.1 - 0.00046 20.6 0.0 0.00077 19.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KZN92713.1 - 0.0053 16.7 0.0 0.0084 16.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Phosphoesterase PF04185.14 KZN92715.1 - 1.9e-61 208.3 1.0 4.1e-61 207.1 1.0 1.5 1 1 0 1 1 1 1 Phosphoesterase family DUF3824 PF12868.7 KZN92716.1 - 7.3e-41 140.3 34.2 7.3e-41 140.3 34.2 10.0 3 2 7 10 10 10 3 Domain of unknwon function (DUF3824) Miga PF10265.9 KZN92716.1 - 0.7 8.8 4.1 24 3.7 0.0 2.4 2 0 0 2 2 2 0 Mitoguardin Vac7 PF12751.7 KZN92717.1 - 3.2e-153 510.7 0.7 3.2e-153 510.7 0.7 2.0 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 CorA PF01544.18 KZN92720.1 - 6.7e-30 104.4 4.2 1.7e-18 67.0 0.4 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein PEP_hydrolase PF09370.10 KZN92721.1 - 1.1e-133 444.5 1.1 1.3e-133 444.3 1.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like NMO PF03060.15 KZN92721.1 - 0.0036 16.7 0.3 0.0036 16.7 0.3 2.0 2 0 0 2 2 2 1 Nitronate monooxygenase S-methyl_trans PF02574.16 KZN92721.1 - 0.0086 15.9 0.1 0.018 14.9 0.1 1.4 1 1 0 1 1 1 1 Homocysteine S-methyltransferase WXG100 PF06013.12 KZN92722.1 - 0.24 11.7 6.3 0.98 9.7 6.3 2.1 1 0 0 1 1 1 0 Proteins of 100 residues with WXG TSC22 PF01166.18 KZN92722.1 - 0.82 10.0 6.7 0.57 10.5 0.4 3.0 3 0 0 3 3 3 0 TSC-22/dip/bun family Allexi_40kDa PF05549.11 KZN92722.1 - 2.1 7.8 4.4 16 4.9 4.4 2.6 1 0 0 1 1 1 0 Allexivirus 40kDa protein adh_short PF00106.25 KZN92723.1 - 3e-38 131.3 0.0 4.5e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN92723.1 - 1.8e-28 99.7 0.0 2.5e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN92723.1 - 5.7e-09 36.1 0.9 1.9e-07 31.2 0.9 2.7 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 KZN92723.1 - 0.073 12.5 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Hydrolase PF00702.26 KZN92723.1 - 0.16 12.2 0.2 26 5.0 0.0 3.0 4 0 0 4 4 4 0 haloacid dehalogenase-like hydrolase Zn_clus PF00172.18 KZN92724.1 - 4.5e-10 39.5 11.6 4.5e-10 39.5 11.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alpha_GJ PF03229.13 KZN92726.1 - 0.0045 17.5 2.3 0.0045 17.5 2.3 2.4 2 0 0 2 2 2 1 Alphavirus glycoprotein J NICE-1 PF15845.5 KZN92726.1 - 0.03 15.1 2.3 0.051 14.3 0.2 2.4 2 0 0 2 2 2 0 Cysteine-rich C-terminal 1 family Gcn1_N PF12074.8 KZN92727.1 - 1.4e-121 406.2 4.2 8.2e-121 403.6 1.2 3.1 2 0 0 2 2 2 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Ribosomal_L19e PF01280.20 KZN92727.1 - 4.6e-60 201.8 7.6 1.2e-59 200.5 7.6 1.8 1 0 0 1 1 1 1 Ribosomal protein L19e HEAT PF02985.22 KZN92727.1 - 2.3e-29 98.9 31.3 0.27 11.6 0.0 21.9 24 0 0 24 24 22 6 HEAT repeat HEAT_EZ PF13513.6 KZN92727.1 - 3.2e-23 81.8 52.4 2.6e-06 27.8 0.1 20.7 19 4 4 23 23 22 6 HEAT-like repeat HEAT_2 PF13646.6 KZN92727.1 - 2.1e-20 72.9 44.2 2.6e-05 24.5 2.8 14.4 10 2 6 17 17 16 6 HEAT repeats Cnd1 PF12717.7 KZN92727.1 - 3.8e-14 53.0 4.9 0.031 14.3 0.1 10.0 10 1 1 12 12 10 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KZN92727.1 - 8.6e-10 39.1 0.0 5.2 7.7 0.0 8.0 6 2 2 8 8 8 1 Vacuolar 14 Fab1-binding region ParcG PF10274.9 KZN92727.1 - 6.1e-09 36.2 2.4 0.043 13.9 0.0 6.1 7 1 0 7 7 5 2 Parkin co-regulated protein CLASP_N PF12348.8 KZN92727.1 - 1.8e-06 27.7 0.0 0.42 10.2 0.0 6.5 5 1 2 7 7 7 1 CLASP N terminal TIP120 PF08623.10 KZN92727.1 - 2e-06 27.7 0.1 0.0022 17.8 0.0 5.0 5 1 0 5 5 5 1 TATA-binding protein interacting (TIP20) IFRD PF05004.13 KZN92727.1 - 0.00022 20.5 18.2 0.063 12.4 1.4 5.8 5 1 1 6 6 6 3 Interferon-related developmental regulator (IFRD) Adaptin_N PF01602.20 KZN92727.1 - 0.0031 16.1 11.6 2.5 6.5 1.6 6.6 6 2 1 7 7 7 1 Adaptin N terminal region MMS19_C PF12460.8 KZN92727.1 - 0.0039 16.4 23.4 0.28 10.3 0.1 7.4 6 1 1 7 7 7 2 RNAPII transcription regulator C-terminal DUF937 PF06078.11 KZN92727.1 - 0.023 15.3 8.8 16 6.1 0.0 6.7 6 1 0 6 6 6 0 Bacterial protein of unknown function (DUF937) FANCI_S2 PF14676.6 KZN92727.1 - 0.03 14.6 1.0 0.85 9.9 0.0 3.9 4 0 0 4 4 3 0 FANCI solenoid 2 TFCD_C PF12612.8 KZN92727.1 - 0.037 13.9 2.0 5.2 6.9 0.0 4.9 4 0 0 4 4 4 0 Tubulin folding cofactor D C terminal Tti2 PF10521.9 KZN92727.1 - 0.06 12.9 3.6 6.5 6.2 0.0 5.4 6 1 0 6 6 6 0 Tti2 family Dopey_N PF04118.14 KZN92727.1 - 0.91 8.6 3.3 71 2.3 0.0 5.3 7 1 1 8 8 8 0 Dopey, N-terminal RIX1 PF08167.12 KZN92727.1 - 5.3 6.7 9.7 9.9 5.9 0.1 5.4 7 0 0 7 7 7 0 rRNA processing/ribosome biogenesis HA2 PF04408.23 KZN92728.1 - 3.1e-16 59.6 0.5 9.9e-16 58.0 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KZN92728.1 - 3.8e-15 56.2 0.1 2.1e-14 53.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KZN92728.1 - 7.2e-11 42.2 0.0 1.4e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KZN92728.1 - 5.7e-06 26.6 0.0 2.6e-05 24.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain DUF3602 PF12223.8 KZN92728.1 - 0.082 13.5 1.1 0.26 11.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) KilA-N PF04383.13 KZN92729.1 - 0.0005 19.9 0.0 0.011 15.6 0.0 2.4 1 1 0 1 1 1 1 KilA-N domain Abhydrolase_6 PF12697.7 KZN92731.1 - 1.3e-13 52.1 0.4 2.4e-13 51.2 0.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KZN92731.1 - 2.2e-05 24.2 0.0 7.2e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KZN92731.1 - 0.0091 15.3 0.1 0.92 8.7 0.0 2.6 2 0 0 2 2 2 2 Serine aminopeptidase, S33 BRCT_2 PF16589.5 KZN92732.1 - 2.6e-05 24.5 0.0 5.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KZN92732.1 - 0.0017 18.6 0.0 0.005 17.1 0.0 1.8 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 KZN92732.1 - 0.11 12.4 3.2 0.22 11.5 0.1 2.4 2 0 0 2 2 2 0 twin BRCT domain Mg_trans_NIPA PF05653.14 KZN92733.1 - 7.7e-90 301.0 27.1 1.1e-89 300.5 27.1 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KZN92733.1 - 1.5e-05 25.2 6.0 1.5e-05 25.2 6.0 3.3 3 0 0 3 3 3 2 EamA-like transporter family DUF805 PF05656.14 KZN92733.1 - 4 7.9 12.9 2.3 8.6 3.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Patatin PF01734.22 KZN92734.1 - 1.6e-15 57.9 0.0 4e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase MOSC PF03473.17 KZN92735.1 - 5.1e-36 123.6 0.0 9e-36 122.8 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KZN92735.1 - 5.8e-13 48.8 0.0 1e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain APH PF01636.23 KZN92736.1 - 5.2e-14 52.8 0.0 3.1e-13 50.2 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN92736.1 - 5.5e-06 26.1 0.0 7.2e-06 25.7 0.0 1.3 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KZN92736.1 - 0.011 15.2 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain SHMT PF00464.19 KZN92737.1 - 4e-198 657.9 0.0 4.7e-198 657.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase KorB PF08535.10 KZN92738.1 - 0.043 13.8 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 KorB domain Flocculin_t3 PF13928.6 KZN92739.1 - 0.0085 16.6 7.6 0.0085 16.6 7.6 3.0 2 1 1 3 3 3 2 Flocculin type 3 repeat FSIP1 PF15554.6 KZN92740.1 - 0.0033 16.6 4.3 0.0042 16.2 4.3 1.1 1 0 0 1 1 1 1 FSIP1 family FA_hydroxylase PF04116.13 KZN92741.1 - 9.4e-23 81.0 10.9 9.4e-23 81.0 10.9 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF4691 PF15762.5 KZN92743.1 - 0.041 14.1 4.4 0.076 13.2 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4691) Fungal_trans_2 PF11951.8 KZN92744.1 - 9.5e-21 74.0 6.2 6.3e-20 71.3 6.2 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN92744.1 - 4.2e-07 30.0 12.2 4.2e-07 30.0 12.2 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN92744.1 - 0.022 13.8 1.3 0.046 12.7 0.5 1.9 2 0 0 2 2 2 0 Fungal specific transcription factor domain Sugar_tr PF00083.24 KZN92745.1 - 1.5e-107 360.2 21.2 1.7e-107 360.1 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN92745.1 - 1.1e-18 67.4 35.1 3.2e-15 55.9 6.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KZN92745.1 - 0.047 12.0 5.4 0.019 13.2 2.1 2.0 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family adh_short_C2 PF13561.6 KZN92746.1 - 4.2e-48 163.9 0.0 5.9e-48 163.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN92746.1 - 1.2e-38 132.5 0.1 1.4e-38 132.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN92746.1 - 3.7e-13 49.8 0.1 5e-13 49.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KZN92746.1 - 4.1e-05 23.1 0.1 0.039 13.4 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family DUF3277 PF11681.8 KZN92746.1 - 0.089 12.7 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) 3Beta_HSD PF01073.19 KZN92746.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KZN92746.1 - 0.16 11.0 0.0 0.22 10.6 0.0 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Cutinase PF01083.22 KZN92747.1 - 5.5e-51 173.0 0.7 6.3e-51 172.8 0.7 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KZN92747.1 - 0.00012 21.7 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 KZN92747.1 - 0.002 18.1 0.0 0.0042 17.0 0.0 1.5 2 0 0 2 2 2 1 Bacterial virulence protein (VirJ) DUF2974 PF11187.8 KZN92747.1 - 0.046 13.3 0.0 0.06 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) FAD_binding_3 PF01494.19 KZN92748.1 - 3.8e-92 309.2 0.0 5.4e-92 308.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KZN92748.1 - 3.3e-57 193.1 0.0 6.4e-57 192.2 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 KZN92748.1 - 0.00015 21.1 0.2 0.00045 19.5 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KZN92748.1 - 0.00042 19.1 0.1 0.0015 17.3 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein SE PF08491.10 KZN92748.1 - 0.00042 19.4 0.0 0.00065 18.8 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_2 PF00890.24 KZN92748.1 - 0.00064 18.9 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KZN92748.1 - 0.0012 18.1 0.0 0.01 15.1 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KZN92748.1 - 0.0032 16.6 0.1 0.0059 15.7 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KZN92748.1 - 0.0052 17.0 0.0 0.016 15.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KZN92748.1 - 0.018 15.6 0.0 0.036 14.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KZN92748.1 - 0.026 14.1 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KZN92748.1 - 0.043 13.1 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KZN92748.1 - 0.16 11.3 0.1 0.32 10.3 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 KZN92748.1 - 0.21 10.6 0.0 0.36 9.9 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A AMP-binding PF00501.28 KZN92749.1 - 3.5e-76 256.5 0.0 4.5e-76 256.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KZN92749.1 - 9.4e-16 57.5 0.6 2.9e-15 55.9 0.6 1.9 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KZN92749.1 - 8.1e-15 55.6 0.1 3.4e-14 53.6 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ras PF00071.22 KZN92750.1 - 1.2e-51 174.5 0.7 7.1e-51 172.0 0.7 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KZN92750.1 - 1.4e-18 67.2 0.1 1.9e-17 63.6 0.1 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KZN92750.1 - 0.00053 19.5 0.1 0.0041 16.6 0.1 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family FeoB_N PF02421.18 KZN92750.1 - 0.011 15.3 0.3 0.23 11.0 0.0 2.5 2 1 1 3 3 3 0 Ferrous iron transport protein B SRPRB PF09439.10 KZN92750.1 - 0.027 13.9 0.1 0.68 9.3 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KZN92750.1 - 0.11 12.4 0.0 9.1 6.1 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Septin PF00735.18 KZN92750.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_25 PF13481.6 KZN92750.1 - 0.13 11.8 0.1 0.33 10.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KZN92750.1 - 0.14 11.6 0.0 6.5 6.2 0.0 2.7 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain DUF1749 PF08538.10 KZN92751.1 - 3.5e-95 318.6 0.0 4.2e-95 318.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) AA_permease PF00324.21 KZN92752.1 - 2e-107 359.7 35.6 2.5e-107 359.4 35.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KZN92752.1 - 3.3e-29 102.0 39.0 4.2e-29 101.6 39.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1612 PF07756.12 KZN92752.1 - 0.056 13.7 2.1 3.5 7.9 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1612) HAD_2 PF13419.6 KZN92753.1 - 3.6e-08 33.7 0.0 4.8e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KZN92753.1 - 2.1e-05 24.9 0.0 2.9e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KZN92753.1 - 7.1e-05 22.8 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Mcp5_PH PF12814.7 KZN92754.1 - 1e-44 151.5 0.0 2e-44 150.6 0.0 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology TPR_MLP1_2 PF07926.12 KZN92754.1 - 0.00039 20.5 15.6 0.016 15.2 10.8 2.4 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 KZN92754.1 - 0.011 16.2 13.6 0.012 16.1 12.1 1.8 1 1 0 1 1 1 0 Fez1 APH PF01636.23 KZN92754.1 - 0.04 13.8 2.2 0.08 12.9 2.2 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family GAS PF13851.6 KZN92754.1 - 0.08 12.3 13.5 0.18 11.1 0.9 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 KZN92754.1 - 0.42 9.4 10.8 0.72 8.7 10.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 KZN92754.1 - 1.9 7.9 12.1 3.3 7.1 12.1 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 UPF0242 PF06785.11 KZN92754.1 - 2 8.5 5.4 4.4 7.4 5.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF724 PF05266.14 KZN92754.1 - 6.6 6.5 8.1 5.4 6.8 6.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Cyt-b5 PF00173.28 KZN92755.1 - 7.3e-22 77.3 0.1 8.1e-22 77.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.8 KZN92755.1 - 0.11 12.7 0.0 0.17 12.0 0.0 1.4 1 1 0 1 1 1 0 V-ATPase subunit H OB_NTP_bind PF07717.16 KZN92756.1 - 4.2e-21 75.1 0.0 1.2e-20 73.7 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KZN92756.1 - 1.6e-19 70.2 0.0 1.6e-19 70.2 0.0 3.3 3 1 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KZN92756.1 - 5.4e-13 49.2 0.0 1.2e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KZN92756.1 - 1.9e-07 31.0 0.2 6.3e-07 29.3 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 KZN92756.1 - 7e-05 22.6 0.0 0.0002 21.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KZN92756.1 - 0.00012 21.2 0.0 0.00029 20.0 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 KZN92756.1 - 0.00018 21.9 0.1 0.0004 20.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KZN92756.1 - 0.00019 21.7 0.0 0.00076 19.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 KZN92756.1 - 0.015 15.4 0.0 0.049 13.8 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain SRP54 PF00448.22 KZN92756.1 - 0.04 13.6 0.2 0.11 12.1 0.2 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 KZN92756.1 - 0.066 13.7 0.0 0.066 13.7 0.0 3.7 1 1 1 2 2 1 0 AAA domain Flavi_DEAD PF07652.14 KZN92756.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain Pkinase PF00069.25 KZN92757.1 - 7.1e-40 137.0 0.0 2.2e-38 132.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KZN92757.1 - 3.3e-23 82.3 0.0 6.3e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Condensation PF00668.20 KZN92758.1 - 4.6e-213 708.0 0.0 6.8e-43 147.0 0.0 6.4 6 1 0 6 6 6 6 Condensation domain AMP-binding PF00501.28 KZN92758.1 - 3e-189 629.0 0.0 1.7e-81 274.0 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme PP-binding PF00550.25 KZN92758.1 - 4.5e-53 177.5 12.4 7.7e-12 45.4 0.1 6.9 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KZN92758.1 - 1.3e-11 45.3 0.0 0.00034 21.5 0.0 4.0 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 KZN92758.1 - 3.1e-05 23.9 0.3 8.2 6.1 0.0 4.4 4 0 0 4 4 4 3 Wax ester synthase-like Acyl-CoA acyltransferase domain Transferase PF02458.15 KZN92758.1 - 0.0027 16.5 0.0 7.4 5.1 0.0 4.9 6 0 0 6 6 6 1 Transferase family K_oxygenase PF13434.6 KZN92759.1 - 1.4e-111 373.0 0.0 4.9e-111 371.2 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KZN92759.1 - 7.6e-06 25.4 0.0 0.00043 19.6 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KZN92759.1 - 1.7e-05 24.3 0.1 0.0036 16.6 0.0 2.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Ank_2 PF12796.7 KZN92760.1 - 5.1e-37 126.3 1.5 1.3e-12 48.1 0.1 3.8 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) DHHC PF01529.20 KZN92760.1 - 1.1e-34 119.4 8.7 1.1e-34 119.4 8.7 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_5 PF13857.6 KZN92760.1 - 7.9e-25 86.6 4.9 9.2e-07 29.0 0.0 5.0 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN92760.1 - 5.8e-21 72.4 3.4 3.7e-07 29.9 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 KZN92760.1 - 4.3e-19 68.0 1.3 5.1e-06 26.7 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KZN92760.1 - 6.2e-19 68.1 2.0 0.00018 22.0 0.0 4.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Cyclin PF08613.11 KZN92763.1 - 8.6e-35 120.5 0.0 1.3e-34 119.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KZN92763.1 - 0.0039 16.9 0.0 0.0061 16.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Na_Ca_ex PF01699.24 KZN92764.1 - 1.6e-22 80.1 30.1 2.5e-13 50.3 9.5 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Formyl_trans_N PF00551.19 KZN92764.1 - 0.061 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Formyl transferase PALP PF00291.25 KZN92765.1 - 1.7e-64 218.1 0.0 2.2e-64 217.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KZN92765.1 - 8.4e-11 42.2 0.0 8.1e-08 32.6 0.0 3.0 3 0 0 3 3 3 2 CBS domain SRPRB PF09439.10 KZN92766.1 - 1e-23 83.7 4.3 3.8e-22 78.6 4.3 2.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KZN92766.1 - 0.0001 22.3 0.1 0.0002 21.4 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KZN92766.1 - 0.00013 21.4 0.1 0.0022 17.5 0.0 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family ATP_bind_1 PF03029.17 KZN92766.1 - 0.0064 16.3 0.1 0.31 10.8 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 KZN92766.1 - 0.011 15.4 1.0 0.025 14.3 0.2 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KZN92766.1 - 0.012 16.0 0.3 0.031 14.6 0.1 1.8 1 1 1 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KZN92766.1 - 0.026 14.8 0.4 0.09 13.0 0.4 1.9 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KZN92766.1 - 0.056 13.1 0.0 0.87 9.3 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain RsgA_GTPase PF03193.16 KZN92766.1 - 0.07 13.0 0.9 0.4 10.6 0.3 2.2 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 KZN92766.1 - 0.071 13.6 0.1 0.14 12.7 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA PF00004.29 KZN92766.1 - 0.33 11.4 1.3 1.2 9.6 1.3 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KRE9 PF05390.11 KZN92767.1 - 4.1e-07 30.7 8.9 5.3e-07 30.3 6.9 2.2 2 0 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 KZN92767.1 - 5.7e-06 27.0 0.0 1.8e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family AA_kinase PF00696.28 KZN92768.1 - 8.8e-39 133.5 0.5 1.2e-38 133.1 0.5 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KZN92768.1 - 3.5e-16 58.9 0.0 4.2e-15 55.5 0.0 2.3 2 0 0 2 2 2 1 PUA domain Peptidase_M76 PF09768.9 KZN92769.1 - 3.1e-74 248.4 2.6 3.7e-74 248.2 2.6 1.1 1 0 0 1 1 1 1 Peptidase M76 family HNH_5 PF14279.6 KZN92769.1 - 0.0023 17.7 0.6 0.023 14.6 0.1 2.4 2 0 0 2 2 2 1 HNH endonuclease SprT-like PF10263.9 KZN92769.1 - 0.53 10.1 3.5 0.43 10.5 1.4 1.8 1 1 1 2 2 2 0 SprT-like family Pkinase PF00069.25 KZN92770.1 - 7.7e-72 241.8 0.0 1.1e-71 241.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN92770.1 - 1.5e-44 152.2 0.0 2.1e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KZN92770.1 - 1.9e-08 34.0 0.0 7.6e-08 32.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KZN92770.1 - 7.9e-05 22.1 0.2 0.00014 21.3 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KZN92770.1 - 0.0075 15.2 0.0 0.0075 15.2 0.0 1.4 2 0 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 KZN92770.1 - 0.056 13.1 0.0 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KZN92770.1 - 0.065 13.2 0.1 0.093 12.6 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KZN92770.1 - 0.085 12.4 0.0 0.23 11.1 0.0 1.7 1 1 1 2 2 2 0 RIO1 family TIP41 PF04176.13 KZN92771.1 - 4.8e-70 234.5 0.0 5.8e-70 234.2 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family DUF4279 PF14106.6 KZN92771.1 - 0.13 12.5 0.0 0.56 10.4 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4279) Ubiq_cyt_C_chap PF03981.12 KZN92772.1 - 2.1e-37 128.3 0.1 1.1e-36 126.0 0.1 1.9 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone MAAL_N PF05034.13 KZN92772.1 - 0.059 13.0 0.0 0.087 12.5 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase N-terminus Peptidase_M1 PF01433.20 KZN92773.1 - 1.5e-45 155.4 0.6 2.2e-45 154.9 0.6 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KZN92773.1 - 1.6e-35 121.6 0.0 3.1e-35 120.7 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KZN92773.1 - 3.9e-29 102.2 0.0 5.7e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 KZN92773.1 - 0.0041 16.8 0.0 0.17 11.5 0.1 2.4 2 0 0 2 2 2 1 Peptidase MA superfamily Peptidase_M61 PF05299.12 KZN92773.1 - 0.088 13.2 2.7 3.4 8.1 2.0 3.1 2 1 0 2 2 2 0 M61 glycyl aminopeptidase MIT PF04212.18 KZN92774.1 - 1.4e-12 47.5 0.4 3.7e-12 46.1 0.4 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Zn_clus PF00172.18 KZN92775.1 - 5.5e-09 36.0 7.2 5.5e-09 36.0 7.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M24 PF00557.24 KZN92776.1 - 9.2e-53 179.0 0.3 1.3e-52 178.5 0.3 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KZN92776.1 - 6.6e-26 90.5 0.0 1.4e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain BTB PF00651.31 KZN92777.1 - 0.0037 17.5 0.0 0.014 15.6 0.0 1.9 2 1 0 2 2 2 1 BTB/POZ domain MBOAT PF03062.19 KZN92778.1 - 6e-43 147.5 15.1 6e-43 147.5 15.1 3.3 2 2 1 3 3 3 2 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KZN92778.1 - 3e-05 24.2 2.6 7.1e-05 23.0 2.6 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DLH PF01738.18 KZN92779.1 - 4.9e-19 68.8 0.0 5.2e-19 68.7 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KZN92779.1 - 0.08 13.5 0.1 0.083 13.5 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family CH PF00307.31 KZN92780.1 - 2.4e-73 243.3 0.0 7.6e-21 74.3 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 KZN92780.1 - 4.9e-06 26.9 1.7 0.0001 22.7 0.3 3.3 3 0 0 3 3 3 1 EF-hand domain pair CAMSAP_CH PF11971.8 KZN92780.1 - 0.00043 20.1 0.0 0.17 11.7 0.0 3.5 3 0 0 3 3 3 1 CAMSAP CH domain EF-hand_6 PF13405.6 KZN92780.1 - 0.022 14.7 2.3 1.3 9.2 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 KZN92780.1 - 0.083 12.5 0.5 11 5.8 0.1 3.4 3 0 0 3 3 3 0 EF hand DDHD PF02862.17 KZN92781.1 - 7.9e-43 147.2 0.0 5.4e-41 141.2 0.0 2.4 2 0 0 2 2 2 2 DDHD domain RNase_3_N PF18497.1 KZN92781.1 - 0.067 13.4 0.0 0.82 9.9 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease III N-terminal domain PXA PF02194.15 KZN92782.1 - 2.7e-35 122.0 0.2 5e-35 121.1 0.2 1.5 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 KZN92782.1 - 1.8e-22 80.0 0.0 8.1e-22 77.9 0.0 2.2 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 KZN92782.1 - 1.2e-10 41.4 0.2 3.5e-09 36.7 0.0 2.4 2 0 0 2 2 2 1 PX domain TPR_14 PF13428.6 KZN92782.1 - 0.092 13.6 0.1 0.42 11.6 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat PC4 PF02229.16 KZN92783.1 - 8.6e-23 79.7 0.1 1.6e-22 78.9 0.1 1.5 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Hydantoinase_B PF02538.14 KZN92784.1 - 8.6e-225 747.0 0.1 1.1e-224 746.6 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KZN92784.1 - 1.7e-101 339.4 0.3 2.7e-101 338.7 0.3 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KZN92784.1 - 3.9e-57 192.8 0.4 2.2e-55 187.1 0.0 2.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region RRM_1 PF00076.22 KZN92785.1 - 9.3e-12 44.6 0.0 1.3e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KZN92785.1 - 0.00065 19.7 0.0 0.00091 19.2 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Mito_carr PF00153.27 KZN92786.1 - 9.7e-74 243.4 1.7 2.2e-24 85.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KZN92786.1 - 0.00012 21.4 0.5 0.0058 15.8 0.0 3.0 2 1 1 4 4 4 1 Gammaproteobacterial serine protease PrcB_C PF14343.6 KZN92786.1 - 0.097 12.8 0.0 2.7 8.2 0.0 2.5 2 0 0 2 2 2 0 PrcB C-terminal Ribosomal_L18 PF17135.4 KZN92787.1 - 7.9e-90 299.3 3.7 9e-90 299.1 3.7 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KZN92787.1 - 0.00074 20.2 0.1 0.0017 19.0 0.1 1.8 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF4276 PF14103.6 KZN92787.1 - 0.028 14.7 0.0 1.7 8.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4276) Aldedh PF00171.22 KZN92788.1 - 3.2e-13 49.0 9.9 8.7e-12 44.3 6.5 2.7 2 1 0 2 2 2 2 Aldehyde dehydrogenase family FA_hydroxylase PF04116.13 KZN92790.1 - 3.1e-25 89.0 17.0 3.1e-25 89.0 17.0 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily NCA2 PF08637.10 KZN92791.1 - 4.3e-102 341.2 0.0 7e-102 340.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Ras PF00071.22 KZN92792.1 - 2.7e-65 218.9 0.0 3.2e-65 218.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KZN92792.1 - 4.8e-34 117.2 0.0 7.2e-34 116.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KZN92792.1 - 6.5e-14 51.8 0.0 8.4e-14 51.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KZN92792.1 - 4.2e-06 26.4 0.0 8.9e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KZN92792.1 - 0.00013 21.4 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KZN92792.1 - 0.00076 19.4 0.2 0.78 9.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KZN92792.1 - 0.004 17.2 0.0 0.008 16.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KZN92792.1 - 0.022 14.3 0.0 0.11 12.0 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.10 KZN92792.1 - 0.039 13.4 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KZN92792.1 - 0.16 12.2 0.0 0.48 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KZN92793.1 - 3.2e-65 218.5 0.0 2.4e-41 141.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KZN92793.1 - 3.9e-20 71.4 0.4 2.5e-13 49.6 0.1 3.0 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KZN92793.1 - 3.8e-12 46.9 2.0 0.0032 17.9 0.0 4.7 3 2 2 5 5 4 2 AAA ATPase domain AAA_5 PF07728.14 KZN92793.1 - 7.5e-09 35.7 0.5 0.0066 16.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.18 KZN92793.1 - 1.8e-07 31.2 0.0 7.7e-06 25.9 0.0 2.8 2 2 0 2 2 2 1 Bacterial dnaA protein AAA_7 PF12775.7 KZN92793.1 - 2e-06 27.5 0.0 0.06 12.9 0.0 2.9 3 0 0 3 3 3 2 P-loop containing dynein motor region Rad17 PF03215.15 KZN92793.1 - 3.9e-06 26.9 0.2 0.0011 19.0 0.0 3.1 2 1 1 3 3 3 1 Rad17 P-loop domain AAA_14 PF13173.6 KZN92793.1 - 4e-06 26.9 0.0 0.051 13.6 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.6 KZN92793.1 - 4.1e-06 26.5 0.7 0.62 9.6 0.0 4.1 3 1 1 4 4 4 2 AAA domain AAA_22 PF13401.6 KZN92793.1 - 4.3e-06 27.0 4.2 0.62 10.3 0.1 4.9 2 2 2 4 4 4 2 AAA domain RuvB_N PF05496.12 KZN92793.1 - 5.7e-06 26.2 0.0 0.013 15.2 0.0 3.5 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KZN92793.1 - 1.6e-05 24.7 0.0 0.018 14.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 KZN92793.1 - 2.2e-05 24.7 0.1 0.12 12.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 KZN92793.1 - 4.1e-05 22.9 0.1 0.019 14.2 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain DUF815 PF05673.13 KZN92793.1 - 8.2e-05 21.9 0.0 0.13 11.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_2 PF07724.14 KZN92793.1 - 0.00011 22.4 0.0 0.016 15.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 KZN92793.1 - 0.00028 21.3 0.0 1.3 9.4 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_24 PF13479.6 KZN92793.1 - 0.00062 19.5 0.0 0.036 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KZN92793.1 - 0.0016 18.4 0.2 0.18 11.7 0.0 3.1 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea AAA_33 PF13671.6 KZN92793.1 - 0.0035 17.5 0.1 4.3 7.5 0.2 2.9 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KZN92793.1 - 0.005 16.7 0.0 1.7 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KZN92793.1 - 0.0056 16.4 0.0 0.53 10.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KZN92793.1 - 0.0089 16.5 0.2 1.2 9.7 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_18 PF13238.6 KZN92793.1 - 0.0096 16.5 0.0 0.44 11.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain CDC48_N PF02359.18 KZN92793.1 - 0.013 15.6 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain Mg_chelatase PF01078.21 KZN92793.1 - 0.02 14.3 0.1 3.7 6.9 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KZN92793.1 - 0.028 14.4 0.0 8 6.5 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TniB PF05621.11 KZN92793.1 - 0.053 12.9 0.0 7.5 5.9 0.0 3.1 3 0 0 3 3 3 0 Bacterial TniB protein SRPRB PF09439.10 KZN92793.1 - 0.054 12.9 0.1 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_19 PF13245.6 KZN92793.1 - 0.065 13.6 0.0 16 5.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KZN92793.1 - 0.074 13.0 5.5 1.1 9.2 0.3 3.4 2 1 1 3 3 3 0 NACHT domain AAA_23 PF13476.6 KZN92793.1 - 0.089 13.3 0.0 0.29 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain Vps4_C PF09336.10 KZN92793.1 - 0.12 12.4 0.0 1.4 8.9 0.0 2.6 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain RRM_1 PF00076.22 KZN92794.1 - 4.3e-13 48.9 0.0 7e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KZN92794.1 - 0.021 14.9 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif PI3_PI4_kinase PF00454.27 KZN92795.1 - 8e-52 176.5 0.4 1.8e-51 175.4 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KZN92795.1 - 1.1e-39 136.6 5.1 3.2e-39 135.1 3.5 2.4 2 0 0 2 2 2 1 FAT domain UME PF08064.13 KZN92795.1 - 2.9e-37 126.7 0.5 1.6e-36 124.3 0.5 2.5 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.20 KZN92795.1 - 8.7e-13 47.8 0.0 2e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 FATC domain TPR_14 PF13428.6 KZN92795.1 - 0.00098 19.8 4.5 8.5 7.5 0.4 4.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KZN92795.1 - 0.0029 18.1 0.7 0.52 10.9 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KZN92795.1 - 0.0046 16.6 1.7 0.13 12.0 0.4 2.6 2 0 0 2 2 2 1 TPR repeat TPR_7 PF13176.6 KZN92795.1 - 0.0062 16.5 0.6 16 5.8 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 KZN92795.1 - 0.085 13.3 1.9 4.4 7.7 0.0 2.8 2 0 0 2 2 2 0 Bacterial transcriptional activator domain YojJ PF10372.9 KZN92795.1 - 0.13 12.4 0.0 1.3 9.2 0.0 2.9 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus ANAPC5 PF12862.7 KZN92795.1 - 0.16 12.1 0.9 8.1 6.6 0.1 3.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 dCMP_cyt_deam_1 PF00383.23 KZN92796.1 - 3.3e-26 91.1 0.1 4.1e-26 90.8 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KZN92796.1 - 2.2e-19 69.6 0.0 2.9e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase XOO_2897-deam PF14440.6 KZN92796.1 - 0.0025 17.9 0.0 0.0037 17.3 0.0 1.2 1 0 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase APOBEC3 PF18771.1 KZN92796.1 - 0.004 17.3 0.0 0.0061 16.7 0.0 1.2 1 0 0 1 1 1 1 APOBEC3 SNAD4 PF18750.1 KZN92796.1 - 0.0087 16.2 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC4_like PF18774.1 KZN92796.1 - 0.014 15.4 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase APOBEC_N PF08210.11 KZN92796.1 - 0.03 14.2 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain Bd3614-deam PF14439.6 KZN92796.1 - 0.032 14.3 1.4 0.22 11.6 1.4 2.0 1 1 0 1 1 1 0 Bd3614-like deaminase APOBEC2 PF18772.1 KZN92796.1 - 0.059 13.4 0.0 0.084 12.9 0.0 1.2 1 0 0 1 1 1 0 APOBEC2 NAD1 PF18778.1 KZN92796.1 - 0.065 13.3 0.0 0.093 12.8 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 NADH-u_ox-rdase PF10785.9 KZN92797.1 - 1.1e-29 102.9 0.1 1.8e-29 102.2 0.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 KZN92797.1 - 3.6e-26 90.9 0.2 4.8e-26 90.5 0.2 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Swi3 PF07962.12 KZN92798.1 - 2.5e-34 117.1 0.5 3.8e-34 116.5 0.5 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Neisseria_TspB PF05616.13 KZN92798.1 - 2.6 6.4 7.1 3.4 6.0 7.1 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein RCC1 PF00415.18 KZN92799.1 - 2e-57 191.6 4.8 1.9e-10 41.2 0.2 7.8 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KZN92799.1 - 2.8e-30 103.4 37.5 1.5e-07 31.0 2.6 6.6 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RibD_C PF01872.17 KZN92800.1 - 2.5e-30 105.8 0.0 3.6e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 RibD C-terminal domain Nic96 PF04097.14 KZN92801.1 - 1e-215 717.9 0.0 1.3e-215 717.6 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.6 KZN92801.1 - 0.065 14.1 44.8 0.1 13.5 32.6 2.6 2 0 0 2 2 2 0 Nucleoporin FG repeat region COX16 PF14138.6 KZN92802.1 - 3.6e-30 104.3 0.1 4.7e-30 103.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Arc_PepC_II PF06847.11 KZN92802.1 - 0.012 16.1 0.0 0.046 14.2 0.0 1.8 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II Y_phosphatase PF00102.27 KZN92803.1 - 4.8e-60 203.0 0.0 3e-59 200.5 0.0 2.1 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 KZN92803.1 - 8.8e-08 32.6 0.0 3.2e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.20 KZN92803.1 - 0.005 16.7 0.2 0.01 15.7 0.2 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KZN92803.1 - 0.0084 16.1 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family F-box PF00646.33 KZN92804.1 - 0.0015 18.4 0.0 0.0032 17.3 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KZN92804.1 - 0.046 13.6 0.2 0.046 13.6 0.2 2.2 3 0 0 3 3 3 0 F-box-like F-box-like_2 PF13013.6 KZN92804.1 - 0.082 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain UPF0370 PF13980.6 KZN92805.1 - 0.17 11.9 0.7 0.32 11.1 0.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) FGGY_C PF02782.16 KZN92806.1 - 1.6e-49 168.3 0.4 2.4e-49 167.8 0.4 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KZN92806.1 - 1.5e-23 83.7 0.1 9.4e-21 74.5 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KZN92806.1 - 0.036 13.6 0.0 0.099 12.1 0.0 1.7 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DEDD_Tnp_IS110 PF01548.17 KZN92806.1 - 0.095 12.6 1.3 1 9.3 0.2 2.3 2 0 0 2 2 2 0 Transposase Na_Ca_ex PF01699.24 KZN92807.1 - 6.8e-23 81.3 23.6 4.1e-15 56.0 10.6 4.0 5 0 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 KZN92807.1 - 3e-14 53.4 10.4 3e-14 53.4 10.4 3.9 3 0 0 3 3 3 1 Inner membrane component domain AAA PF00004.29 KZN92808.1 - 1e-42 145.7 0.0 1.7e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KZN92808.1 - 4.7e-14 51.9 0.0 1e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KZN92808.1 - 3.8e-07 30.2 0.0 1e-06 28.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KZN92808.1 - 4.2e-07 30.2 0.0 8.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KZN92808.1 - 3.3e-06 27.6 0.0 0.00016 22.1 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KZN92808.1 - 6.2e-05 23.3 0.2 0.023 15.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain Prot_ATP_ID_OB PF16450.5 KZN92808.1 - 0.00016 21.5 2.5 0.00038 20.3 2.5 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_18 PF13238.6 KZN92808.1 - 0.00051 20.6 0.0 0.03 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KZN92808.1 - 0.00058 19.6 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KZN92808.1 - 0.0058 16.8 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KZN92808.1 - 0.0061 15.8 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain ATPase PF06745.13 KZN92808.1 - 0.0068 15.8 0.0 0.022 14.1 0.0 1.8 2 0 0 2 2 2 1 KaiC IstB_IS21 PF01695.17 KZN92808.1 - 0.0072 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KZN92808.1 - 0.012 15.0 0.1 0.03 13.7 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KZN92808.1 - 0.018 14.9 0.0 0.051 13.4 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KZN92808.1 - 0.023 14.4 0.0 0.046 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KZN92808.1 - 0.03 13.8 0.0 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein TsaE PF02367.17 KZN92808.1 - 0.036 14.1 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KZN92808.1 - 0.043 13.0 0.0 0.076 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) HR1 PF02185.16 KZN92808.1 - 0.043 13.9 0.5 0.11 12.7 0.5 1.6 1 0 0 1 1 1 0 Hr1 repeat Sigma54_activat PF00158.26 KZN92808.1 - 0.052 13.3 0.0 0.22 11.2 0.0 2.0 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_7 PF12775.7 KZN92808.1 - 0.06 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KZN92808.1 - 0.062 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 KZN92808.1 - 0.08 12.5 0.1 0.22 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF2072 PF09845.9 KZN92808.1 - 0.083 13.2 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein AAA_14 PF13173.6 KZN92808.1 - 0.084 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KZN92808.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Prot_ATP_OB_N PF17758.1 KZN92808.1 - 0.14 11.8 0.4 0.48 10.1 0.1 2.1 2 0 0 2 2 1 0 Proteasomal ATPase OB N-terminal domain Zeta_toxin PF06414.12 KZN92808.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin F-box-like PF12937.7 KZN92809.1 - 0.0029 17.5 0.1 0.008 16.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like UFD1 PF03152.14 KZN92810.1 - 2.9e-26 92.0 0.0 6.7e-21 74.5 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 KZN92810.1 - 6.1e-07 29.6 0.1 2.1e-06 27.9 0.1 1.9 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zinc_ribbon_4 PF13717.6 KZN92810.1 - 0.29 11.1 5.9 11 6.1 0.4 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Yip1 PF04893.17 KZN92811.1 - 2.4e-07 30.7 16.2 8.4e-06 25.6 8.9 2.4 2 1 0 2 2 2 2 Yip1 domain Bac_surface_Ag PF01103.23 KZN92812.1 - 9.6e-42 143.6 0.6 1.2e-41 143.3 0.6 1.1 1 0 0 1 1 1 1 Surface antigen UQ_con PF00179.26 KZN92813.1 - 5e-19 68.3 0.1 7.6e-19 67.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Fungal_trans_2 PF11951.8 KZN92814.1 - 2.3e-14 53.0 0.1 3.4e-14 52.5 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cyto_heme_lyase PF01265.17 KZN92815.1 - 2.7e-127 424.3 1.7 3.1e-127 424.1 1.7 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase ABC1 PF03109.16 KZN92816.1 - 3.3e-21 75.6 0.0 5.6e-12 45.9 0.0 2.6 1 1 1 2 2 2 2 ABC1 family RIO1 PF01163.22 KZN92816.1 - 0.01 15.5 0.0 0.54 9.8 0.0 2.3 2 0 0 2 2 2 1 RIO1 family Raf1_HTH PF18579.1 KZN92816.1 - 0.021 14.5 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain Pox_ser-thr_kin PF05445.11 KZN92816.1 - 0.21 10.5 0.0 0.33 9.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase KAP PF05804.12 KZN92818.1 - 0.008 14.4 0.0 0.093 10.9 0.0 2.2 2 0 0 2 2 2 1 Kinesin-associated protein (KAP) DUF383 PF04063.14 KZN92818.1 - 0.078 12.6 0.1 1.4 8.6 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF383) DPM3 PF08285.11 KZN92819.1 - 2.7e-32 110.8 0.4 3e-32 110.7 0.4 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Phage_holin_3_6 PF07332.11 KZN92819.1 - 0.12 12.5 8.2 2 8.4 3.3 2.1 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Pribosyltran PF00156.27 KZN92820.1 - 3.1e-07 30.0 0.0 4.6e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Acyl-CoA_dh_2 PF08028.11 KZN92821.1 - 1.3e-09 38.4 0.1 1.3e-09 38.4 0.1 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KZN92821.1 - 6.4e-07 30.0 0.0 1.1e-06 29.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KZN92821.1 - 3e-06 27.3 0.0 7e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KZN92821.1 - 0.0081 16.4 1.1 0.035 14.3 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain EAP30 PF04157.16 KZN92822.1 - 3.5e-70 236.0 0.0 3.9e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Peptidase_M50 PF02163.22 KZN92822.1 - 0.0096 15.2 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M50 HTH_6 PF01418.17 KZN92822.1 - 0.015 15.2 0.0 0.14 12.2 0.0 2.2 1 1 1 2 2 2 0 Helix-turn-helix domain, rpiR family HTH_27 PF13463.6 KZN92822.1 - 0.15 12.6 0.0 0.45 11.1 0.0 1.8 2 0 0 2 2 2 0 Winged helix DNA-binding domain Ribosomal_L30_N PF08079.12 KZN92823.1 - 4e-26 91.0 13.8 7.1e-26 90.3 13.8 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KZN92823.1 - 1.3e-17 63.4 1.9 3.2e-17 62.1 1.9 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e PRK PF00485.18 KZN92824.1 - 0.0058 16.4 0.0 0.0091 15.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 KZN92824.1 - 0.028 13.7 0.0 0.056 12.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin KAP_NTPase PF07693.14 KZN92824.1 - 0.034 13.4 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain MobB PF03205.14 KZN92824.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MeaB PF03308.16 KZN92824.1 - 0.084 11.8 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KZN92824.1 - 0.092 13.1 0.0 0.19 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KZN92824.1 - 0.11 13.1 0.0 0.35 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF4419 PF14388.6 KZN92824.1 - 0.17 11.3 0.6 0.25 10.7 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4419) SRP_SPB PF02978.19 KZN92824.1 - 0.22 12.2 0.0 0.47 11.1 0.0 1.5 1 0 0 1 1 1 0 Signal peptide binding domain adh_short PF00106.25 KZN92825.1 - 4.1e-82 274.4 8.6 7e-45 152.9 0.6 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KZN92825.1 - 1.6e-65 220.9 5.9 1.1e-34 120.0 0.3 2.5 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 KZN92825.1 - 7.4e-34 116.0 0.0 1.5e-33 115.0 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 KZN92825.1 - 4.3e-25 88.7 4.5 1.3e-11 44.7 0.9 2.5 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 KZN92825.1 - 0.00055 19.3 0.2 0.0016 17.8 0.2 1.8 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_N PF00056.23 KZN92825.1 - 0.019 15.1 0.8 2.6 8.1 0.9 2.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Epimerase PF01370.21 KZN92825.1 - 0.033 13.7 1.4 1.8 8.0 0.1 2.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family IBR PF01485.21 KZN92826.1 - 0.00096 19.3 5.4 0.00096 19.3 5.4 4.7 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain MFS_1 PF07690.16 KZN92828.1 - 6e-41 140.5 41.0 6e-41 140.5 41.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KZN92828.1 - 8.3e-18 64.1 24.4 1.1e-17 63.8 24.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KZN92828.1 - 9.9e-14 51.0 8.1 9.9e-14 51.0 8.1 2.5 2 1 1 3 3 3 2 Sugar (and other) transporter PALP PF00291.25 KZN92829.1 - 3.3e-32 112.1 0.0 5.9e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.20 KZN92829.1 - 4.8e-06 27.1 0.0 2.1e-05 25.0 0.0 2.1 1 0 0 1 1 1 1 Rhodanese-like domain Ferric_reduct PF01794.19 KZN92830.1 - 1.9e-20 73.2 15.2 1.9e-20 73.2 15.2 2.7 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KZN92830.1 - 1.8e-14 53.7 0.0 7e-14 51.8 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 KZN92830.1 - 3.1e-10 40.4 0.0 4.7e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF4405 PF14358.6 KZN92830.1 - 0.0017 18.9 12.2 0.084 13.4 2.9 3.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4405) Cys_Met_Meta_PP PF01053.20 KZN92832.1 - 3.8e-140 466.8 0.0 4.4e-140 466.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 KZN92832.1 - 6.4e-05 21.6 0.0 0.00029 19.5 0.0 1.8 1 1 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.19 KZN92832.1 - 0.0012 17.9 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KZN92832.1 - 0.0041 16.5 0.1 0.0099 15.2 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KZN92832.1 - 0.027 13.8 0.0 0.071 12.4 0.0 1.6 2 0 0 2 2 2 0 Beta-eliminating lyase Na_H_Exchanger PF00999.21 KZN92833.1 - 2.4e-30 105.6 35.7 8.4e-25 87.4 24.3 3.0 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family Pex14_N PF04695.13 KZN92833.1 - 0.029 15.0 2.1 9.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TraV PF09676.10 KZN92833.1 - 0.11 13.5 0.3 0.11 13.5 0.3 1.6 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Fst_toxin PF13955.6 KZN92833.1 - 0.56 10.2 0.1 0.56 10.2 0.1 3.1 3 0 0 3 3 3 0 Toxin Fst, type I toxin-antitoxin system Fungal_trans PF04082.18 KZN92835.1 - 6.2e-34 117.2 0.0 3.9e-33 114.6 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN92835.1 - 1.6e-07 31.3 8.8 2.6e-07 30.6 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PigN PF04987.14 KZN92836.1 - 1.2e-165 551.9 33.3 1.2e-165 551.9 33.3 1.4 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Sulfatase PF00884.23 KZN92836.1 - 6.6e-10 38.9 0.2 2.4e-09 37.0 0.1 1.9 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 KZN92836.1 - 1.6e-08 34.5 4.8 5.8e-07 29.4 4.8 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KZN92836.1 - 0.0016 17.9 0.0 0.0026 17.2 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Csm1 PF12539.8 KZN92837.1 - 5.3e-30 103.9 0.1 9.5e-30 103.1 0.1 1.4 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 AAA_13 PF13166.6 KZN92837.1 - 0.0061 15.3 2.4 0.0096 14.6 2.4 1.3 1 0 0 1 1 1 1 AAA domain APG6_N PF17675.1 KZN92837.1 - 0.02 15.4 12.2 0.02 15.4 12.2 2.2 3 0 0 3 3 1 0 Apg6 coiled-coil region Vps5 PF09325.10 KZN92837.1 - 0.035 13.6 3.6 0.079 12.5 3.6 1.6 1 0 0 1 1 1 0 Vps5 C terminal like DUF3138 PF11336.8 KZN92837.1 - 0.11 11.1 6.2 0.18 10.4 6.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF5094 PF17015.5 KZN92837.1 - 0.76 9.9 0.0 0.76 9.9 0.0 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF5094) Baculo_PEP_C PF04513.12 KZN92837.1 - 1.1 9.2 7.7 1.1 9.3 5.6 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF724 PF05266.14 KZN92837.1 - 1.4 8.7 6.2 3.1 7.6 6.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) GAS PF13851.6 KZN92837.1 - 1.7 7.9 14.9 1.1 8.6 9.3 2.7 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2968 PF11180.8 KZN92837.1 - 1.8 8.1 16.4 0.18 11.4 11.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Spc7 PF08317.11 KZN92837.1 - 3.3 6.5 15.6 9.9 4.9 15.1 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein PKcGMP_CC PF16808.5 KZN92837.1 - 3.9 7.4 8.6 0.15 11.9 0.8 2.7 2 1 1 3 3 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF3450 PF11932.8 KZN92837.1 - 5.8 6.1 18.0 0.43 9.9 6.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) COG2 PF06148.11 KZN92837.1 - 6.3 6.9 6.9 21 5.2 5.5 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA PF00004.29 KZN92838.1 - 8.5e-37 126.5 0.0 1.7e-36 125.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KZN92838.1 - 1.2e-08 34.6 0.0 2.4e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KZN92838.1 - 3.3e-05 23.7 0.0 7.5e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KZN92838.1 - 4.1e-05 24.0 0.8 0.00095 19.6 0.0 2.6 2 1 0 3 3 2 1 AAA ATPase domain AAA_14 PF13173.6 KZN92838.1 - 5.3e-05 23.3 0.0 0.00011 22.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KZN92838.1 - 8.2e-05 22.6 0.2 0.00097 19.2 0.2 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KZN92838.1 - 8.6e-05 23.1 0.0 0.0011 19.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KZN92838.1 - 0.00015 21.9 0.0 0.00033 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KZN92838.1 - 0.00032 21.0 0.1 0.012 15.9 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KZN92838.1 - 0.00053 20.2 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KZN92838.1 - 0.00081 18.8 0.1 0.0015 18.0 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KZN92838.1 - 0.00098 18.9 0.0 0.0028 17.4 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KZN92838.1 - 0.0012 19.2 0.0 0.0034 17.7 0.0 1.9 1 1 0 1 1 1 1 RNA helicase TniB PF05621.11 KZN92838.1 - 0.0018 17.7 0.0 1.7 8.0 0.0 2.5 1 1 1 2 2 2 2 Bacterial TniB protein AAA_25 PF13481.6 KZN92838.1 - 0.0026 17.4 0.2 0.051 13.1 0.1 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KZN92838.1 - 0.0059 16.5 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_28 PF13521.6 KZN92838.1 - 0.0069 16.6 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KZN92838.1 - 0.011 15.5 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 KZN92838.1 - 0.025 14.7 0.0 0.062 13.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Rad17 PF03215.15 KZN92838.1 - 0.03 14.2 0.1 0.08 12.9 0.1 1.6 1 1 1 2 2 2 0 Rad17 P-loop domain Sigma54_activat PF00158.26 KZN92838.1 - 0.035 13.8 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 KZN92838.1 - 0.035 13.2 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 KZN92838.1 - 0.045 13.6 0.0 0.2 11.6 0.0 1.9 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea CPT PF07931.12 KZN92838.1 - 0.048 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.27 KZN92838.1 - 0.049 14.2 0.2 0.12 12.9 0.0 1.9 2 1 0 2 2 1 0 ABC transporter AAA_7 PF12775.7 KZN92838.1 - 0.05 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 KZN92838.1 - 0.066 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 KZN92838.1 - 0.099 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 KZN92838.1 - 0.13 11.5 0.0 0.55 9.5 0.0 1.9 1 1 1 2 2 2 0 KaiC Guanylate_kin PF00625.21 KZN92838.1 - 0.18 11.5 0.0 1.8 8.2 0.0 2.5 2 1 0 3 3 3 0 Guanylate kinase COesterase PF00135.28 KZN92840.1 - 2.5e-81 274.1 0.0 3.3e-80 270.4 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KZN92840.1 - 7.3e-06 26.0 0.0 2.7e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KZN92840.1 - 0.00082 18.9 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family FKBP_C PF00254.28 KZN92841.1 - 6.6e-25 87.3 0.0 7.9e-25 87.0 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PHP PF02811.19 KZN92842.1 - 1.6e-15 57.8 0.0 5.5e-15 56.1 0.0 1.8 1 1 0 1 1 1 1 PHP domain ACPS PF01648.20 KZN92843.1 - 1e-11 45.0 0.0 1.5e-11 44.4 0.0 1.3 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 KZN92843.1 - 0.011 15.8 0.2 5 7.3 0.0 2.5 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase N-terminal domain FGF-BP1 PF06473.12 KZN92843.1 - 0.09 12.6 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) ATP19 PF11022.8 KZN92844.1 - 5e-29 100.5 0.1 6.1e-29 100.2 0.1 1.1 1 0 0 1 1 1 1 ATP synthase subunit K MTP18 PF10558.9 KZN92845.1 - 1.3e-79 266.1 0.7 1.5e-79 265.9 0.1 1.4 2 0 0 2 2 2 1 Mitochondrial 18 KDa protein (MTP18) DIT1_PvcA PF05141.12 KZN92846.1 - 5.6e-80 268.8 0.0 7.3e-80 268.4 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein FAM193_C PF15914.5 KZN92846.1 - 0.025 14.3 0.1 0.06 13.1 0.1 1.7 1 1 0 1 1 1 0 FAM193 family C-terminal MFS_1 PF07690.16 KZN92847.1 - 1.3e-24 86.8 36.6 1.3e-24 86.8 36.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DIT1_PvcA PF05141.12 KZN92848.1 - 4.1e-87 292.2 0.0 6e-87 291.6 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein Ribonuc_L-PSP PF01042.21 KZN92850.1 - 3.3e-37 127.2 0.0 4.3e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP TEA PF01285.18 KZN92851.1 - 0.14 12.3 0.0 0.55 10.3 0.0 2.0 2 0 0 2 2 2 0 TEA/ATTS domain EAP30 PF04157.16 KZN92852.1 - 8.8e-42 143.0 0.1 1.2e-41 142.6 0.1 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36-NZF-N PF16988.5 KZN92852.1 - 1.5e-23 81.9 2.5 1.5e-23 81.9 2.5 2.4 2 1 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Vps36_ESCRT-II PF11605.8 KZN92852.1 - 8.8e-23 80.3 0.0 1.7e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-Sec23_Sec24 PF04810.15 KZN92852.1 - 3.4e-05 23.8 4.8 0.003 17.6 0.7 2.4 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger zf-RanBP PF00641.18 KZN92852.1 - 0.00016 20.9 11.3 0.001 18.3 0.9 2.7 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others GRAM PF02893.20 KZN92852.1 - 0.0011 18.9 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 GRAM domain DZR PF12773.7 KZN92852.1 - 0.19 11.8 4.6 0.14 12.2 0.4 2.3 2 0 0 2 2 2 0 Double zinc ribbon SAC3_GANP PF03399.16 KZN92853.1 - 1e-23 84.2 0.9 1.4e-21 77.1 0.9 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KZN92853.1 - 0.0012 18.9 0.1 0.0025 17.8 0.1 1.5 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SH3_1 PF00018.28 KZN92854.1 - 5.1e-26 90.0 0.0 1.5e-11 43.7 0.0 2.8 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KZN92854.1 - 6.4e-15 54.8 0.1 5.1e-07 29.5 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 KZN92854.1 - 6.8e-14 51.8 0.0 1.7e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.17 KZN92854.1 - 2.2e-08 33.7 0.0 7.7e-05 22.3 0.0 2.8 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.24 KZN92854.1 - 3.5e-06 26.9 0.6 7.1e-06 25.9 0.6 1.5 1 0 0 1 1 1 1 PB1 domain AFG1_ATPase PF03969.16 KZN92855.1 - 3.4e-96 322.3 0.0 1.8e-91 306.8 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 KZN92855.1 - 0.002 18.5 0.1 0.7 10.2 0.0 3.2 3 1 1 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 KZN92855.1 - 0.002 18.4 0.0 0.011 16.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 KZN92855.1 - 0.0049 16.7 0.6 1.3 8.8 0.1 2.4 2 1 0 2 2 2 2 Bacterial dnaA protein AAA_14 PF13173.6 KZN92855.1 - 0.01 15.9 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KZN92855.1 - 0.011 16.1 0.0 0.048 14.1 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KZN92855.1 - 0.014 15.8 0.0 0.094 13.1 0.0 2.4 3 0 0 3 3 3 0 RNA helicase Catalase PF00199.19 KZN92856.1 - 1.9e-165 550.6 0.2 2.3e-165 550.3 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KZN92856.1 - 4.9e-19 68.3 0.0 1.2e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 KZN92856.1 - 1e-08 35.0 0.1 2e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 KZN92856.1 - 1.9e-07 31.0 0.0 3.3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Potyvirid-P3 PF13608.6 KZN92856.1 - 0.051 12.6 0.0 0.14 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein P3 of Potyviral polyprotein Cation_efflux PF01545.21 KZN92857.1 - 8.8e-39 133.3 1.0 1.4e-38 132.6 1.0 1.3 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.16 KZN92857.1 - 0.99 8.5 8.4 0.029 13.5 2.0 1.6 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component Amidase PF01425.21 KZN92858.1 - 1.5e-100 337.3 0.0 2.4e-100 336.6 0.0 1.3 1 1 0 1 1 1 1 Amidase Methyltransf_11 PF08241.12 KZN92859.1 - 8.6e-12 45.5 0.0 1.6e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN92859.1 - 1.4e-10 41.7 0.0 3.7e-10 40.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN92859.1 - 2.1e-05 25.2 0.0 3.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN92859.1 - 5.7e-05 23.0 0.0 8.3e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KZN92859.1 - 0.0025 17.6 0.0 0.0043 16.8 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Acetyltransf_3 PF13302.7 KZN92860.1 - 2.3e-14 54.3 0.0 3.1e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KZN92860.1 - 0.00022 21.4 0.0 0.00031 21.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KZN92860.1 - 0.022 14.9 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 KZN92861.1 - 1.5e-23 83.3 48.0 1.9e-23 83.0 48.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Chitin_synth_1 PF01644.17 KZN92862.1 - 1.3e-77 259.4 0.0 2.2e-77 258.6 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KZN92862.1 - 3e-26 91.2 0.1 6.4e-26 90.1 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KZN92862.1 - 8.2e-23 80.8 1.7 7e-20 71.1 0.0 2.4 1 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KZN92862.1 - 1.1e-06 28.8 0.2 1.1e-06 28.8 0.2 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KZN92862.1 - 0.0073 16.2 0.0 0.037 13.9 0.0 2.0 1 1 1 2 2 2 1 Glycosyltransferase like family 2 Caps_synth_CapC PF14102.6 KZN92862.1 - 0.84 10.1 9.4 0.054 13.9 0.6 2.5 2 0 0 2 2 2 0 Capsule biosynthesis CapC DUF1774 PF08611.10 KZN92863.1 - 2e-33 114.6 2.2 2e-33 114.6 2.2 2.2 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1774) Inositol_P PF00459.25 KZN92864.1 - 1.8e-39 135.9 0.1 4.5e-39 134.6 0.1 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family Cupin_3 PF05899.12 KZN92865.1 - 5.3e-06 26.0 0.0 1.1e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.12 KZN92865.1 - 6.1e-05 22.8 0.0 6.5e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Peptidase_M28 PF04389.17 KZN92866.1 - 6.7e-30 104.3 0.1 1.1e-29 103.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KZN92866.1 - 4.5e-08 33.0 0.1 9.6e-08 32.0 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 R3H-assoc PF13902.6 KZN92867.1 - 2.1e-23 83.2 2.2 6e-23 81.7 2.2 1.8 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 KZN92867.1 - 0.014 15.4 0.5 0.098 12.7 0.0 2.3 2 0 0 2 2 2 0 R3H domain DND1_DSRM PF14709.7 KZN92869.1 - 0.044 14.0 0.5 2.2 8.6 0.0 2.5 2 1 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 MFS_1 PF07690.16 KZN92870.1 - 1.5e-25 89.9 35.2 2.2e-25 89.3 35.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TGT PF01702.18 KZN92871.1 - 1.1e-142 475.3 0.0 1.3e-142 475.1 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Thymidylat_synt PF00303.19 KZN92872.1 - 4.2e-103 344.1 0.0 4.8e-103 344.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase zf-AN1 PF01428.16 KZN92873.1 - 2.3e-21 75.7 29.5 1.8e-11 44.0 9.9 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 KZN92873.1 - 0.018 15.2 6.9 0.018 15.2 6.9 2.6 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Transp_Tc5_C PF04236.15 KZN92873.1 - 0.021 15.2 15.3 0.25 11.7 3.6 2.2 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zinc_ribbon_4 PF13717.6 KZN92873.1 - 0.23 11.4 8.9 1.3 9.0 0.6 2.7 2 0 0 2 2 2 0 zinc-ribbon domain C1_4 PF07975.12 KZN92873.1 - 1.5 9.1 22.5 8.3 6.7 5.3 3.4 2 2 0 2 2 2 0 TFIIH C1-like domain Ada_Zn_binding PF02805.16 KZN92876.1 - 3.8e-28 97.3 3.3 6.2e-28 96.6 3.3 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 KZN92876.1 - 9.8e-07 28.7 0.0 1.8e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 KZN92876.1 - 0.0035 17.6 0.0 0.009 16.3 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KZN92876.1 - 0.015 15.3 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix MFS_1 PF07690.16 KZN92877.1 - 3.1e-32 111.9 36.0 3.8e-32 111.6 36.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN92877.1 - 2.9e-08 33.0 16.9 2.7e-05 23.2 0.2 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter Phage_holin_3_6 PF07332.11 KZN92877.1 - 0.26 11.3 0.1 0.26 11.3 0.1 3.4 4 0 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III Aldo_ket_red PF00248.21 KZN92878.1 - 1.7e-71 240.9 0.0 1.9e-71 240.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans_2 PF11951.8 KZN92879.1 - 2e-05 23.6 2.5 3.3e-05 22.9 2.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tfb2 PF03849.14 KZN92880.1 - 1.1e-135 452.3 0.0 1.7e-135 451.6 0.0 1.3 2 0 0 2 2 2 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KZN92880.1 - 7.3e-24 84.0 0.6 1.4e-23 83.1 0.6 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KZN92880.1 - 5.1e-05 23.4 0.1 0.00047 20.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Aquarius_N PF16399.5 KZN92881.1 - 0 1075.0 0.0 0 1074.7 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 KZN92881.1 - 4.1e-26 91.8 0.0 7.2e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KZN92881.1 - 3.5e-21 76.2 0.0 1.1e-20 74.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KZN92881.1 - 1.2e-07 31.7 0.0 0.00032 20.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KZN92881.1 - 1.7e-06 28.4 0.0 5.3e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KZN92881.1 - 2.5e-06 27.6 0.0 6.5e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KZN92881.1 - 0.0015 18.4 0.1 0.27 10.9 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DnaB_C PF03796.15 KZN92881.1 - 0.0024 17.2 0.0 0.018 14.4 0.0 2.4 3 0 0 3 3 3 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 KZN92881.1 - 0.0032 17.9 0.1 0.019 15.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain UvrD_C_2 PF13538.6 KZN92881.1 - 0.0074 16.1 1.5 0.04 13.8 0.4 2.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA PF00004.29 KZN92881.1 - 0.016 15.6 0.0 0.055 13.9 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 KZN92881.1 - 0.022 14.3 0.0 0.065 12.7 0.0 1.8 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_5 PF07728.14 KZN92881.1 - 0.031 14.3 0.0 0.53 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 KZN92881.1 - 0.036 13.3 1.0 0.061 12.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KZN92881.1 - 0.049 13.9 0.6 0.41 10.9 0.4 2.5 1 1 1 2 2 2 0 AAA domain DEAD PF00270.29 KZN92881.1 - 0.068 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase PIF1 PF05970.14 KZN92881.1 - 0.083 12.0 0.0 3.8 6.6 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase Adeno_IVa2 PF02456.15 KZN92881.1 - 0.093 11.5 0.1 0.27 10.0 0.0 1.7 2 0 0 2 2 2 0 Adenovirus IVa2 protein SMC_N PF02463.19 KZN92881.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_7 PF12775.7 KZN92881.1 - 0.19 11.2 0.0 0.41 10.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region efThoc1 PF11957.8 KZN92882.1 - 5.2e-153 510.2 3.3 8.9e-153 509.5 3.3 1.3 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Homeodomain PF00046.29 KZN92883.1 - 1.1e-16 60.3 4.1 2.3e-16 59.4 4.1 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KZN92883.1 - 0.07 13.0 0.2 0.22 11.5 0.2 1.9 1 0 0 1 1 1 0 Homeobox KN domain Adaptin_N PF01602.20 KZN92885.1 - 5.1e-125 418.0 4.4 6.6e-125 417.6 4.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KZN92885.1 - 3.1e-44 149.8 0.0 7.1e-44 148.6 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KZN92885.1 - 4.6e-16 59.1 0.0 1.2e-15 57.7 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain RTP1_C1 PF10363.9 KZN92885.1 - 0.098 12.9 0.4 0.59 10.3 0.1 2.6 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Coatomer_g_Cpla PF16381.5 KZN92885.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Coatomer subunit gamma-1 C-terminal appendage platform Ala_racemase_N PF01168.20 KZN92886.1 - 2.3e-19 69.9 0.0 2.9e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Hist_deacetyl PF00850.19 KZN92888.1 - 1.5e-48 165.9 0.0 3.1e-48 164.8 0.0 1.5 1 1 0 1 1 1 1 Histone deacetylase domain RTP801_C PF07809.11 KZN92888.1 - 0.026 14.4 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 RTP801 C-terminal region SLAC1 PF03595.17 KZN92889.1 - 7e-76 255.6 47.2 8.2e-76 255.3 47.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel ATP-grasp_2 PF08442.10 KZN92890.1 - 5.7e-76 254.6 0.5 1.2e-75 253.5 0.1 1.7 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 KZN92890.1 - 9e-25 87.3 0.3 1.7e-24 86.4 0.3 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KZN92890.1 - 4.2e-08 32.9 0.1 1.3e-07 31.4 0.1 1.8 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KZN92890.1 - 0.0022 17.8 0.9 0.12 12.1 0.1 2.7 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain F-box PF00646.33 KZN92891.1 - 1.6e-06 27.9 4.4 4.2e-06 26.5 1.7 2.6 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KZN92891.1 - 0.00055 19.8 0.6 0.0013 18.6 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KZN92891.1 - 0.00062 19.6 0.4 0.0016 18.3 0.4 1.6 1 0 0 1 1 1 1 F-box HSF_DNA-bind PF00447.17 KZN92892.1 - 3e-30 104.7 0.3 4.9e-30 104.0 0.3 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding DUF3245 PF11595.8 KZN92893.1 - 6.8e-49 166.2 8.6 6.8e-49 166.2 8.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3245) Ribosomal_60s PF00428.19 KZN92893.1 - 0.016 15.8 12.0 0.016 15.8 12.0 3.5 2 1 2 4 4 4 0 60s Acidic ribosomal protein p450 PF00067.22 KZN92894.1 - 2.3e-68 231.0 0.0 2.8e-68 230.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Alpha-amylase PF00128.24 KZN92895.1 - 3.6e-20 72.8 0.0 4.4e-20 72.5 0.0 1.0 1 0 0 1 1 1 1 Alpha amylase, catalytic domain HA2 PF04408.23 KZN92897.1 - 2.1e-09 37.6 0.0 6e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) DUF2452 PF10504.9 KZN92897.1 - 0.12 11.9 0.0 4.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2452) Oxidored-like PF09791.9 KZN92898.1 - 2.2e-23 81.6 3.1 4e-23 80.8 3.1 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF5522 PF17653.1 KZN92898.1 - 0.045 13.7 2.2 0.087 12.8 2.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5522) Ribosomal_L13e PF01294.18 KZN92900.1 - 1.3e-76 256.5 7.0 1.8e-76 256.0 7.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e CEP19 PF14933.6 KZN92901.1 - 0.14 12.4 3.4 3.4 7.9 1.5 2.3 2 0 0 2 2 2 0 CEP19-like protein Tmemb_cc2 PF10267.9 KZN92901.1 - 0.35 10.0 8.5 0.039 13.1 4.0 1.5 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein LRR_4 PF12799.7 KZN92902.1 - 1.3e-30 104.9 53.7 1.1e-05 25.7 0.2 10.8 4 3 8 13 13 13 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KZN92902.1 - 5.5e-24 83.7 48.3 1e-08 34.8 4.5 8.2 5 2 4 9 9 9 8 Leucine rich repeat LRR_1 PF00560.33 KZN92902.1 - 3.4e-09 36.0 38.4 0.51 11.1 0.3 13.2 13 1 0 13 13 13 4 Leucine Rich Repeat LRR_9 PF14580.6 KZN92902.1 - 6.1e-08 32.4 14.8 0.086 12.3 1.8 5.2 3 2 2 5 5 5 5 Leucine-rich repeat CSTF_C PF14304.6 KZN92902.1 - 0.033 13.8 0.2 0.2 11.3 0.2 2.4 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal LRR_6 PF13516.6 KZN92902.1 - 0.035 14.2 34.8 5.8 7.2 0.0 9.7 11 0 0 11 11 11 0 Leucine Rich repeat GCIP PF13324.6 KZN92903.1 - 1.4e-23 83.9 2.6 2.8e-23 82.9 2.6 1.5 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting PEX11 PF05648.14 KZN92903.1 - 0.019 14.4 0.2 0.075 12.5 0.1 1.9 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) Sigma70_ner PF04546.13 KZN92903.1 - 0.68 9.8 5.8 0.21 11.4 1.9 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region YL1 PF05764.13 KZN92903.1 - 1.2 9.2 8.1 0.18 11.9 3.7 1.8 2 0 0 2 2 2 0 YL1 nuclear protein DUF5453 PF17534.2 KZN92904.1 - 1.2 9.1 21.5 0.69 9.9 19.6 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5453) Abhydrolase_1 PF00561.20 KZN92905.1 - 2.5e-15 56.8 0.0 5.5e-12 45.9 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KZN92905.1 - 2e-08 33.8 0.0 3.4e-08 33.0 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KZN92905.1 - 3.4e-08 34.4 0.0 4.5e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KZN92905.1 - 1.2e-06 27.5 0.0 2.2e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Ndr family Retro_M PF02813.14 KZN92905.1 - 0.14 12.6 0.1 5.5 7.5 0.0 2.7 3 0 0 3 3 3 0 Retroviral M domain Actin PF00022.19 KZN92906.1 - 2.9e-104 348.9 0.0 1.5e-103 346.6 0.0 1.8 1 1 0 1 1 1 1 Actin 3HCDH_N PF02737.18 KZN92907.1 - 7.3e-51 172.6 1.7 9.4e-51 172.2 1.7 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KZN92907.1 - 4.2e-33 113.8 0.0 1.3e-32 112.2 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 KZN92907.1 - 0.0012 19.1 0.3 0.0031 17.8 0.3 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 KZN92907.1 - 0.0013 18.9 0.7 0.0027 17.9 0.3 1.7 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 KZN92907.1 - 0.0054 16.4 0.2 0.027 14.1 0.1 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA DAO PF01266.24 KZN92907.1 - 0.015 14.9 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KZN92907.1 - 0.027 13.8 1.1 0.056 12.7 1.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KZN92907.1 - 0.032 13.4 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KZN92907.1 - 0.078 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KZN92907.1 - 0.09 12.1 0.2 0.26 10.6 0.1 1.7 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TfuA PF07812.12 KZN92907.1 - 0.1 12.3 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 TfuA-like protein TIMELESS PF04821.14 KZN92908.1 - 3.2e-88 295.6 0.0 7.9e-88 294.3 0.0 1.7 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.13 KZN92908.1 - 2.3e-61 208.7 28.6 2e-59 202.2 1.0 4.2 2 1 1 3 3 3 2 Timeless protein C terminal region PAP_RNA-bind PF04926.15 KZN92908.1 - 0.21 11.2 2.6 1.1 8.9 0.0 2.8 2 0 0 2 2 2 0 Poly(A) polymerase predicted RNA binding domain PhzC-PhzF PF02567.16 KZN92909.1 - 6.3e-44 150.5 0.0 7.6e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein DUF1857 PF08982.11 KZN92910.1 - 8.2e-51 171.7 0.1 9.2e-51 171.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Lipocalin PF00061.23 KZN92910.1 - 0.08 13.1 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Mannosidase_ig PF17786.1 KZN92910.1 - 0.1 13.2 0.1 0.19 12.4 0.1 1.3 1 0 0 1 1 1 0 Mannosidase Ig/CBM-like domain Flagellin_N PF00669.20 KZN92911.1 - 0.12 12.5 0.1 5.8 7.0 0.0 2.0 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region 2OG-FeII_Oxy PF03171.20 KZN92912.1 - 4.7e-13 49.5 0.0 1.2e-12 48.1 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MF_alpha_N PF05436.11 KZN92913.1 - 0.15 12.0 0.2 0.23 11.4 0.2 1.3 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus 2OG-FeII_Oxy_3 PF13640.6 KZN92914.1 - 2.7e-07 31.4 0.0 1.7e-06 28.8 0.0 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Med27 PF11571.8 KZN92915.1 - 7.2e-20 71.1 0.0 1.3e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 27 DUF2924 PF11149.8 KZN92915.1 - 0.028 14.8 0.2 0.053 13.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) SNF2_N PF00176.23 KZN92919.1 - 4.5e-66 222.9 0.0 7e-66 222.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KZN92919.1 - 3.3e-18 66.0 0.0 1.7e-17 63.8 0.0 2.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KZN92919.1 - 4.5e-07 30.0 0.0 1.4e-06 28.4 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KZN92919.1 - 8.2e-05 21.9 0.0 0.00016 21.0 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Pkinase PF00069.25 KZN92920.1 - 9.4e-49 166.1 0.1 2.9e-48 164.5 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN92920.1 - 5.3e-21 75.1 0.0 1.1e-20 74.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KZN92920.1 - 0.0018 18.2 0.1 0.0018 18.2 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KZN92920.1 - 0.012 15.2 0.4 0.069 12.7 0.0 2.0 1 1 1 2 2 2 0 RIO1 family Kdo PF06293.14 KZN92920.1 - 0.14 11.4 0.2 0.68 9.3 0.0 2.0 2 1 1 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family eIF-3c_N PF05470.12 KZN92921.1 - 2.7e-163 544.5 21.3 2.7e-163 544.5 21.3 2.8 2 1 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KZN92921.1 - 2.3e-12 47.4 2.0 3.1e-11 43.7 0.0 3.3 2 1 0 3 3 3 1 PCI domain DUF1385 PF07136.11 KZN92921.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) RRP7 PF12923.7 KZN92921.1 - 0.076 13.1 4.9 3.5 7.8 2.1 2.8 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain SDA1 PF05285.12 KZN92921.1 - 7 6.0 21.8 14 5.0 21.8 1.4 1 0 0 1 1 1 0 SDA1 DASH_Ask1 PF08655.10 KZN92922.1 - 0.18 11.7 0.0 0.43 10.5 0.0 1.6 1 0 0 1 1 1 0 DASH complex subunit Ask1 NmrA PF05368.13 KZN92924.1 - 1.3e-16 60.8 0.0 2.1e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KZN92924.1 - 2e-12 47.4 0.0 3.2e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KZN92924.1 - 6.4e-07 29.1 0.3 1.5e-06 27.8 0.1 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KZN92924.1 - 0.0015 17.7 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KZN92924.1 - 0.0036 16.5 0.1 0.0049 16.0 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KZN92924.1 - 0.0078 15.6 0.0 0.088 12.2 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KZN92924.1 - 0.0094 15.4 0.1 0.018 14.5 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 KZN92924.1 - 0.024 14.9 0.1 0.058 13.7 0.1 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KZN92924.1 - 0.041 13.8 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 KR domain DUF3842 PF12953.7 KZN92924.1 - 0.087 13.2 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) CbiJ PF02571.14 KZN92924.1 - 0.15 11.5 0.1 0.23 10.9 0.1 1.2 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK LpxI_N PF17930.1 KZN92924.1 - 0.15 11.9 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 LpxI N-terminal domain NAD_binding_7 PF13241.6 KZN92924.1 - 0.16 12.4 0.0 0.3 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding LysM PF01476.20 KZN92925.1 - 1.5e-08 34.5 0.1 2.1e-08 34.1 0.1 1.2 1 0 0 1 1 1 1 LysM domain Zn_clus PF00172.18 KZN92926.1 - 2.4e-09 37.2 9.8 3.6e-09 36.6 9.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CoA_transf_3 PF02515.17 KZN92927.1 - 3.5e-38 131.7 1.1 4e-37 128.2 0.7 2.1 2 0 0 2 2 2 2 CoA-transferase family III Alpha-L-AF_C PF06964.12 KZN92928.1 - 2.1e-23 83.3 0.0 5.7e-23 81.9 0.0 1.8 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 KZN92928.1 - 0.0075 16.5 1.8 0.0075 16.5 1.8 2.6 2 1 0 2 2 2 1 Carbohydrate binding domain CTP_synth_N PF06418.14 KZN92931.1 - 7.9e-113 376.2 0.1 1.1e-112 375.7 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KZN92931.1 - 8.5e-48 162.6 0.0 1.5e-47 161.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KZN92931.1 - 5e-08 33.0 0.1 1.6e-07 31.3 0.1 1.9 1 1 0 1 1 1 1 Peptidase C26 GHMP_kinases_N PF00288.26 KZN92932.1 - 2.2e-15 56.6 0.0 4.7e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KZN92932.1 - 1.2e-07 32.0 0.0 3.6e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 KZN92932.1 - 0.0016 18.0 0.1 0.0031 17.0 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature AA_permease PF00324.21 KZN92933.1 - 8e-55 186.3 31.3 1e-54 185.9 31.3 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 KZN92933.1 - 3.3e-20 72.5 0.9 1.4e-06 27.6 0.0 3.3 3 0 0 3 3 3 3 Solute carrier family 12 Aa_trans PF01490.18 KZN92934.1 - 1.8e-85 287.1 31.0 2.2e-85 286.8 31.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MPC PF03650.13 KZN92935.1 - 8.6e-23 80.6 0.0 9.4e-23 80.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers LSM PF01423.22 KZN92936.1 - 5.7e-16 58.0 0.0 6.8e-16 57.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain Ribosomal_L5_C PF00673.21 KZN92937.1 - 6.5e-22 77.5 0.0 9.6e-22 77.0 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KZN92937.1 - 4.5e-18 65.3 0.0 1.9e-17 63.3 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 Sugar_tr PF00083.24 KZN92938.1 - 2.3e-29 102.5 25.1 4.6e-27 95.0 25.1 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN92938.1 - 2.7e-28 98.9 35.8 1.3e-23 83.5 13.0 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 KZN92938.1 - 0.013 14.3 13.7 0.0038 16.1 9.9 2.0 2 1 0 2 2 2 0 LacY proton/sugar symporter Clathrin PF00637.20 KZN92939.1 - 1.2e-196 644.5 34.6 3.7e-31 107.9 0.4 7.6 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 KZN92939.1 - 1.8e-37 125.8 0.3 1.2e-08 34.8 0.1 6.7 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 KZN92939.1 - 6.3e-30 102.9 3.7 7.9e-30 102.6 0.3 3.1 3 0 0 3 3 3 1 Clathrin-H-link TPR_7 PF13176.6 KZN92939.1 - 0.0031 17.4 2.4 64 3.9 0.0 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KZN92939.1 - 0.0062 16.7 6.9 0.38 11.1 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KZN92939.1 - 0.026 14.8 0.8 42 4.5 0.0 4.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KZN92939.1 - 0.039 14.8 10.4 1.8 9.6 0.1 6.6 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KZN92939.1 - 0.068 13.0 0.4 6.6 6.7 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Pox_F16 PF04708.12 KZN92939.1 - 0.095 12.1 0.7 0.24 10.8 0.7 1.6 1 0 0 1 1 1 0 Poxvirus F16 protein Vps39_1 PF10366.9 KZN92939.1 - 0.11 12.8 8.3 15 5.9 0.0 6.0 5 1 1 6 6 6 0 Vacuolar sorting protein 39 domain 1 TPR_2 PF07719.17 KZN92939.1 - 0.14 12.4 3.9 7.8 6.9 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Utp13 PF08625.11 KZN92939.1 - 0.87 9.5 8.5 4.2 7.3 0.2 4.9 4 1 1 5 5 5 0 Utp13 specific WD40 associated domain CPSase_L_D2 PF02786.17 KZN92940.1 - 2.8e-78 262.3 0.1 4.6e-78 261.6 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KZN92940.1 - 4.5e-67 225.6 0.0 8.3e-67 224.8 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KZN92940.1 - 5.3e-40 136.4 0.1 1e-39 135.5 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KZN92940.1 - 1.5e-30 105.5 0.0 5e-30 103.8 0.0 2.0 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KZN92940.1 - 7.5e-27 94.5 0.0 1.6e-26 93.4 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 KZN92940.1 - 2.3e-17 62.6 4.6 2.4e-17 62.5 2.2 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KZN92940.1 - 6.2e-11 42.0 3.8 3.3e-06 26.8 0.1 3.5 2 1 1 3 3 3 2 Biotin-lipoyl like ATP-grasp PF02222.22 KZN92940.1 - 1e-07 31.7 0.0 2.2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KZN92940.1 - 1.7e-07 31.0 0.0 3.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KZN92940.1 - 4.2e-06 26.9 0.0 1.4e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain HlyD_D23 PF16576.5 KZN92940.1 - 4.6e-05 22.7 0.1 0.0091 15.2 0.0 2.5 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 KZN92940.1 - 0.0007 20.3 0.2 4.8 7.9 0.0 3.4 3 0 0 3 3 3 2 HlyD family secretion protein RnfC_N PF13375.6 KZN92940.1 - 0.033 14.2 1.5 1.3 9.0 0.2 2.5 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain GARS_A PF01071.19 KZN92940.1 - 0.033 13.9 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 KZN92940.1 - 0.089 12.4 0.0 0.29 10.7 0.0 1.7 1 1 0 1 1 1 0 RimK-like ATP-grasp domain GCV_H PF01597.19 KZN92940.1 - 0.13 12.2 2.1 0.64 9.9 0.3 2.8 2 1 1 3 3 3 0 Glycine cleavage H-protein COesterase PF00135.28 KZN92941.1 - 2e-49 168.8 0.0 2.6e-49 168.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KZN92941.1 - 2.6e-06 27.4 0.0 3.5e-05 23.8 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold cNMPbd_u2 PF16643.5 KZN92942.1 - 0.065 13.7 1.5 0.079 13.4 1.0 1.3 1 1 0 1 1 1 0 Unstructured region on cNMP-binding protein Fungal_trans_2 PF11951.8 KZN92943.1 - 2.5e-20 72.6 8.2 1.5e-13 50.4 0.3 2.9 4 0 0 4 4 4 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN92943.1 - 3.3e-05 23.9 1.2 5.7e-05 23.1 1.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF924 PF06041.11 KZN92944.1 - 4.2e-55 186.7 0.0 5.2e-55 186.4 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Sulfatase PF00884.23 KZN92945.1 - 9.5e-20 71.2 0.8 3.2e-19 69.5 0.6 1.8 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 KZN92945.1 - 3.5e-07 30.1 0.0 6.1e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KZN92945.1 - 0.003 16.2 0.0 0.0045 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) CD225 PF04505.12 KZN92945.1 - 0.042 14.0 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Interferon-induced transmembrane protein Shadoo PF14999.6 KZN92945.1 - 0.12 12.4 0.2 11 6.1 0.2 2.5 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective PPTA PF01239.22 KZN92946.1 - 1e-33 114.1 25.7 1e-07 31.5 1.3 5.6 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_14 PF13428.6 KZN92946.1 - 0.032 15.0 1.4 2.3 9.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4614 PF15391.6 KZN92946.1 - 0.072 13.1 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF4269 PF14091.6 KZN92946.1 - 0.083 13.1 0.1 0.17 12.1 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4269) PALP PF00291.25 KZN92947.1 - 8.3e-48 163.3 0.5 1.4e-47 162.5 0.5 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme tRNA-synt_1g PF09334.11 KZN92948.1 - 1.6e-94 316.9 0.1 7.6e-93 311.4 0.0 2.5 2 1 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KZN92948.1 - 6.4e-22 77.5 0.1 2.8e-11 42.4 0.0 3.2 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KZN92948.1 - 1.9e-11 43.9 0.1 4.8e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 KZN92948.1 - 0.00011 22.2 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA NTF2 PF02136.20 KZN92949.1 - 2.8e-06 27.9 0.3 1.1e-05 26.0 0.3 1.8 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 KZN92949.1 - 0.00044 20.2 0.0 0.0013 18.7 0.0 1.8 1 1 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Ish1 PF10281.9 KZN92950.1 - 7.1e-06 26.2 0.0 9.2e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein EF-hand_6 PF13405.6 KZN92951.1 - 1.3 9.2 2.9 1 9.5 0.1 2.2 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 KZN92951.1 - 1.3 8.7 5.2 0.36 10.5 0.2 2.3 2 0 0 2 2 2 0 EF hand Cupin_2 PF07883.11 KZN92953.1 - 9.7e-14 50.8 1.4 1.5e-13 50.3 0.7 1.7 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 KZN92953.1 - 5.7e-05 23.0 0.0 9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KZN92953.1 - 0.00027 20.6 0.4 0.00043 19.9 0.2 1.5 2 0 0 2 2 2 1 Cupin Cupin_3 PF05899.12 KZN92953.1 - 0.0015 18.2 0.1 0.0031 17.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.7 KZN92953.1 - 0.002 17.9 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 Cupin MannoseP_isomer PF01050.18 KZN92953.1 - 0.013 15.3 0.1 0.019 14.9 0.1 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase JmjC PF02373.22 KZN92953.1 - 0.033 14.6 0.0 0.083 13.3 0.0 1.7 1 0 0 1 1 1 0 JmjC domain, hydroxylase ARD PF03079.14 KZN92953.1 - 0.043 14.0 0.0 0.076 13.2 0.0 1.4 1 0 0 1 1 1 0 ARD/ARD' family Ribosomal_L38e PF01781.18 KZN92954.1 - 7.3e-33 112.5 2.9 8.3e-33 112.3 2.9 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Glyco_hydro_61 PF03443.14 KZN92956.1 - 3.9e-70 236.0 0.0 4.6e-70 235.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Acetyltransf_3 PF13302.7 KZN92957.1 - 9.2e-15 55.5 0.0 1.3e-14 55.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KZN92957.1 - 0.051 13.5 0.0 3.9 7.5 0.0 2.3 2 0 0 2 2 2 0 FR47-like protein DNA_pol_E_B PF04042.16 KZN92958.1 - 1.8e-44 151.6 0.0 4.2e-44 150.4 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KZN92958.1 - 2.5e-35 121.4 0.0 3.9e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain NMO PF03060.15 KZN92959.1 - 7.6e-53 180.0 1.9 1.1e-52 179.5 1.9 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KZN92959.1 - 9.3e-09 34.7 1.4 9.3e-09 34.7 1.4 1.9 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KZN92959.1 - 0.0053 15.8 2.9 0.0093 15.0 2.9 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase PEP_hydrolase PF09370.10 KZN92959.1 - 0.043 13.0 0.0 0.079 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like Glu_synthase PF01645.17 KZN92959.1 - 0.079 12.1 0.7 0.16 11.1 0.7 1.4 1 0 0 1 1 1 0 Conserved region in glutamate synthase Taxilin PF09728.9 KZN92960.1 - 1.7e-84 283.7 47.6 2.1e-56 191.4 26.5 2.6 3 0 0 3 3 3 2 Myosin-like coiled-coil protein SLATT_4 PF18186.1 KZN92960.1 - 0.73 9.5 14.1 0.38 10.4 1.3 3.2 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 4 UPF0242 PF06785.11 KZN92960.1 - 0.86 9.7 48.8 1.8 8.7 11.8 3.8 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus ADIP PF11559.8 KZN92960.1 - 2.5 8.2 50.8 1.2 9.2 10.8 4.3 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 KZN92960.1 - 3.5 8.3 33.9 0.71 10.5 5.5 4.3 3 1 1 4 4 4 0 Initiation control protein YabA Laminin_II PF06009.12 KZN92960.1 - 4.4 7.3 32.3 4.4 7.3 6.7 4.1 2 2 2 4 4 4 0 Laminin Domain II NCD2 PF04905.13 KZN92960.1 - 6.3 6.8 15.0 0.25 11.3 1.1 3.3 2 1 1 3 3 3 0 NAB conserved region 2 (NCD2) PI3K_P85_iSH2 PF16454.5 KZN92960.1 - 9.6 5.8 37.2 21 4.7 18.9 3.4 2 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain M16C_assoc PF08367.11 KZN92961.1 - 1.7e-73 246.9 0.0 2.9e-73 246.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 KZN92961.1 - 1.8e-20 73.7 0.0 3.9e-14 53.1 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KZN92961.1 - 4.5e-09 36.5 0.0 2.6e-08 34.0 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DUF5566 PF17721.1 KZN92962.1 - 3.7 7.8 7.2 10 6.3 0.6 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5566) Methyltransf_25 PF13649.6 KZN92963.1 - 0.00053 20.6 0.1 0.00082 20.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN92963.1 - 0.025 15.3 0.4 0.04 14.7 0.4 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KZN92963.1 - 0.04 14.6 0.0 0.066 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KZN92963.1 - 0.64 9.8 2.5 2.1 8.1 2.5 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 KZN92966.1 - 2.6e-50 170.6 0.0 3.9e-50 170.0 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_2 PF00891.18 KZN92966.1 - 0.077 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain MTS PF05175.14 KZN92966.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Orn_Arg_deC_N PF02784.16 KZN92967.1 - 4.1e-82 275.3 0.0 5.4e-82 274.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KZN92967.1 - 2.9e-19 69.1 0.0 4.8e-19 68.4 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain cobW PF02492.19 KZN92968.1 - 7.6e-29 100.5 0.0 9.4e-14 51.4 0.0 2.3 1 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KZN92968.1 - 0.002 18.0 0.0 0.0093 15.9 0.0 2.1 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.14 KZN92968.1 - 0.0025 17.7 0.0 0.0053 16.7 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 KZN92968.1 - 0.01 16.4 0.0 0.036 14.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KZN92968.1 - 0.034 14.4 0.0 0.075 13.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 KZN92968.1 - 0.052 13.0 0.0 0.12 11.8 0.0 1.5 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_29 PF13555.6 KZN92968.1 - 0.17 11.6 0.4 1.5 8.6 0.2 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 KZN92968.1 - 0.17 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DSBA PF01323.20 KZN92969.1 - 7.1e-22 78.1 0.0 8e-22 77.9 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain T2SSK PF03934.13 KZN92969.1 - 0.017 14.5 0.0 0.022 14.1 0.0 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K DIOX_N PF14226.6 KZN92971.1 - 8.2e-19 68.5 0.1 5.2e-18 65.9 0.0 2.1 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KZN92971.1 - 9.1e-10 38.9 0.0 2.1e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4581 PF15167.6 KZN92971.1 - 0.16 12.1 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4581) MFS_1 PF07690.16 KZN92972.1 - 4.5e-30 104.8 23.9 4.5e-30 104.8 23.9 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily Abhydrolase_6 PF12697.7 KZN92973.1 - 1e-08 36.1 0.9 1.7e-08 35.4 0.7 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KZN92973.1 - 4.6e-06 26.1 0.0 1.5e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KZN92973.1 - 0.0026 17.7 0.0 0.004 17.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KZN92973.1 - 0.0032 17.1 0.0 0.0048 16.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Na_Pi_cotrans PF02690.15 KZN92973.1 - 0.036 14.2 0.1 0.059 13.5 0.1 1.3 1 0 0 1 1 1 0 Na+/Pi-cotransporter Cutinase PF01083.22 KZN92973.1 - 0.079 12.9 0.0 0.16 11.9 0.0 1.5 1 1 0 1 1 1 0 Cutinase Use1 PF09753.9 KZN92974.1 - 3.1 7.5 6.1 6.7 6.3 6.1 1.5 1 0 0 1 1 1 0 Membrane fusion protein Use1 TLD PF07534.16 KZN92975.1 - 2.7e-22 79.5 0.0 7.4e-22 78.1 0.0 1.8 2 0 0 2 2 2 1 TLD DUF1773 PF08593.10 KZN92975.1 - 2.6e-05 25.1 1.1 7.2e-05 23.7 1.1 1.8 1 0 0 1 1 1 1 Domain of unknown function IMPDH PF00478.25 KZN92977.1 - 9.5e-125 416.2 4.3 1.1e-124 415.9 4.3 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KZN92977.1 - 4.7e-18 65.4 0.1 6.5e-09 36.1 0.1 2.6 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 KZN92977.1 - 1.1e-06 28.3 11.5 0.0015 18.0 1.3 3.2 2 1 1 3 3 3 2 Nitronate monooxygenase FMN_dh PF01070.18 KZN92977.1 - 8.4e-06 25.0 2.2 1.7e-05 24.0 2.2 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 KZN92977.1 - 0.00012 21.6 3.7 0.0048 16.4 3.7 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 KZN92977.1 - 0.0043 16.2 1.4 0.14 11.2 0.3 2.3 1 1 1 2 2 2 1 Dihydrouridine synthase (Dus) ThiG PF05690.14 KZN92977.1 - 0.052 12.8 0.4 0.052 12.8 0.4 2.2 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG Aldolase PF01081.19 KZN92977.1 - 0.15 11.5 1.6 0.29 10.5 0.4 1.9 1 1 0 2 2 2 0 KDPG and KHG aldolase RTA1 PF04479.13 KZN92978.1 - 3.5e-44 150.9 4.3 4e-44 150.7 4.3 1.0 1 0 0 1 1 1 1 RTA1 like protein DUF4087 PF13316.6 KZN92978.1 - 0.028 14.9 0.0 0.92 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4087) NMT_C PF02799.15 KZN92979.1 - 2e-90 301.9 0.1 3.7e-90 301.0 0.0 1.5 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KZN92979.1 - 4.1e-75 251.0 0.2 6.7e-74 247.0 0.0 2.1 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 KZN92979.1 - 7e-07 29.4 0.1 6.3e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF3024 PF11225.8 KZN92979.1 - 0.03 14.6 1.2 3.6 7.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3024) NTP_transf_9 PF04248.12 KZN92979.1 - 0.053 13.4 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF427) Acetyltransf_1 PF00583.25 KZN92979.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Mur_ligase_M PF08245.12 KZN92980.1 - 6.1e-09 36.1 0.8 2.8e-06 27.4 0.3 3.3 2 1 0 2 2 2 1 Mur ligase middle domain Syja_N PF02383.18 KZN92981.1 - 5.9e-91 305.1 0.0 7.4e-91 304.8 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain VirB3 PF05101.13 KZN92981.1 - 0.64 10.3 5.8 1.8 8.9 5.8 1.7 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein Ras PF00071.22 KZN92982.1 - 6.4e-59 198.2 0.2 7.4e-59 198.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KZN92982.1 - 1.2e-36 125.5 0.2 3.3e-36 124.1 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KZN92982.1 - 8.2e-15 54.7 0.0 1e-14 54.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KZN92982.1 - 3.6e-07 29.8 0.0 4.4e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KZN92982.1 - 6.4e-07 29.1 0.0 8.9e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KZN92982.1 - 1.3e-06 28.4 0.0 2.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KZN92982.1 - 2.5e-05 24.2 1.3 0.15 12.0 0.2 2.4 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 KZN92982.1 - 0.015 15.7 0.1 0.033 14.6 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KZN92982.1 - 0.028 14.7 0.0 1.6 9.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain Mitofilin PF09731.9 KZN92983.1 - 2.1e-152 509.2 34.0 1.4e-124 417.2 35.8 2.0 1 1 1 2 2 2 2 Mitochondrial inner membrane protein Med30 PF11315.8 KZN92983.1 - 0.18 12.0 8.2 0.23 11.7 6.6 2.1 1 1 0 1 1 1 0 Mediator complex subunit 30 Sld5 PF05916.11 KZN92983.1 - 2 8.9 7.3 4.6 7.7 1.9 2.5 1 1 1 2 2 2 0 GINS complex protein GTP_EFTU PF00009.27 KZN92986.1 - 3e-58 196.6 0.2 4.8e-58 195.9 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KZN92986.1 - 1.2e-32 111.8 0.0 2.6e-32 110.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 KZN92986.1 - 1.3e-32 112.1 0.1 2.6e-32 111.1 0.1 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KZN92986.1 - 9.1e-24 83.3 0.0 2.2e-23 82.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KZN92986.1 - 7e-13 48.8 0.0 1.6e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KZN92986.1 - 7.2e-06 25.9 0.0 1.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Ribosomal_L36 PF00444.18 KZN92987.1 - 1.2e-10 41.3 2.7 2.9e-10 40.2 2.7 1.6 1 0 0 1 1 1 1 Ribosomal protein L36 PALP PF00291.25 KZN92988.1 - 2.9e-76 256.7 0.1 3.7e-76 256.3 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KZN92988.1 - 3.5e-44 148.5 0.0 6.7e-21 73.9 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase HIG_1_N PF04588.13 KZN92989.1 - 1.1e-27 96.0 0.2 1.6e-27 95.4 0.2 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region SPT16 PF08644.11 KZN92989.1 - 0.14 12.4 0.4 0.21 11.8 0.4 1.2 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) ATP-synt_E PF05680.12 KZN92989.1 - 0.83 10.0 6.7 2.6 8.4 6.7 1.9 1 1 0 1 1 1 0 ATP synthase E chain MARVEL PF01284.23 KZN92990.1 - 7.4e-13 48.8 7.9 1e-12 48.3 7.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain Pkinase PF00069.25 KZN92991.1 - 1.1e-51 175.8 0.0 1.3e-51 175.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN92991.1 - 1.4e-22 80.3 0.0 1.7e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KZN92991.1 - 1.3e-05 24.4 0.0 1.7e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KZN92991.1 - 3.1e-05 23.4 0.1 4.7e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KZN92991.1 - 0.00093 18.6 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KZN92991.1 - 0.0023 17.5 0.1 0.0034 17.0 0.1 1.2 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 KZN92991.1 - 0.0028 17.3 0.0 0.0041 16.8 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KZN92991.1 - 0.0045 17.0 0.0 0.0084 16.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KZN92991.1 - 0.19 10.5 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Complex1_LYR PF05347.15 KZN92992.1 - 2.5e-15 56.2 0.1 4.6e-15 55.4 0.0 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KZN92992.1 - 2.1e-07 31.6 0.1 3e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Aldedh PF00171.22 KZN92993.1 - 3.6e-166 553.3 0.3 4.1e-166 553.1 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RRN9 PF10680.9 KZN92995.1 - 5.1e-12 45.9 2.3 5.1e-12 45.9 2.3 2.8 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor zf-C2H2_aberr PF17017.5 KZN92995.1 - 0.28 11.3 0.0 0.47 10.6 0.0 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger PD40 PF07676.12 KZN92996.1 - 4.5e-41 138.0 24.8 1.6e-07 31.1 0.4 9.6 9 0 0 9 9 9 8 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 KZN92996.1 - 3.9e-14 52.2 1.9 0.00035 19.5 0.2 6.3 5 1 0 6 6 6 5 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF3748 PF12566.8 KZN92996.1 - 0.00045 20.2 0.8 8.7 6.3 0.0 5.3 4 1 2 6 6 6 1 Protein of unknown function (DUF3748) WD40 PF00400.32 KZN92996.1 - 0.0073 17.1 8.9 4.7 8.3 0.1 6.4 6 2 1 7 7 7 1 WD domain, G-beta repeat GspH PF12019.8 KZN92996.1 - 8.2 6.9 17.4 1.1 9.7 0.3 4.9 2 2 2 4 4 4 0 Type II transport protein GspH KR PF08659.10 KZN92997.1 - 5.6e-27 94.8 0.3 8.3e-27 94.3 0.3 1.2 1 0 0 1 1 1 1 KR domain YchF-GTPase_C PF06071.13 KZN92998.1 - 4e-36 123.1 0.0 9.6e-36 121.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KZN92998.1 - 9.2e-21 74.1 0.0 2.3e-20 72.8 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KZN92998.1 - 1.4e-06 27.9 0.0 2.5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Peptidase_S64 PF08192.11 KZN92999.1 - 0.014 14.0 0.1 0.029 12.9 0.0 1.6 2 0 0 2 2 2 0 Peptidase family S64 Trypsin_2 PF13365.6 KZN92999.1 - 0.17 12.8 0.0 3.7 8.4 0.0 2.6 1 1 0 1 1 1 0 Trypsin-like peptidase domain NAD_binding_2 PF03446.15 KZN93000.1 - 1.7e-17 64.0 0.0 2.6e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KZN93000.1 - 1.5e-06 28.5 0.0 2.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DUF3405 PF11885.8 KZN93001.1 - 1.1e-110 370.7 1.1 4e-109 365.6 1.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) DUF3405 PF11885.8 KZN93002.1 - 3.8e-07 29.1 1.8 3.8e-07 29.1 1.8 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3405) Pescadillo_N PF06732.11 KZN93003.1 - 1.9e-124 414.6 0.0 1.9e-124 414.6 0.0 1.7 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 KZN93003.1 - 0.00015 22.1 0.0 0.00085 19.7 0.0 2.2 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KZN93003.1 - 0.021 15.2 0.0 0.19 12.1 0.0 2.6 3 1 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KZN93003.1 - 0.12 12.7 0.0 0.34 11.2 0.0 1.8 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain Astro_capsid_p PF12226.8 KZN93003.1 - 0.75 8.9 21.7 0.016 14.4 12.3 2.4 2 0 0 2 2 2 0 Turkey astrovirus capsid protein PIG-U PF06728.13 KZN93004.1 - 6.9e-121 403.9 23.4 7.9e-121 403.7 23.4 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Mannosyl_trans PF05007.13 KZN93004.1 - 6.8e-05 22.9 0.3 0.00013 21.9 0.4 1.5 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) 8TM_micro PF17028.5 KZN93004.1 - 0.85 9.3 7.4 3.3 7.3 7.4 1.9 1 1 0 1 1 1 0 8TM Microsporidial transmembrane domain Acetyltransf_1 PF00583.25 KZN93005.1 - 2.7e-14 53.4 0.0 4.1e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KZN93005.1 - 2.3e-07 30.8 0.0 3.8e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KZN93005.1 - 3.1e-07 30.7 0.1 4.9e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KZN93005.1 - 6e-06 26.1 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein APH PF01636.23 KZN93006.1 - 6.6e-12 45.9 0.0 1.8e-11 44.4 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN93006.1 - 0.0014 18.2 0.0 0.0037 16.9 0.0 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 KZN93006.1 - 0.012 14.4 0.0 0.82 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Kdo PF06293.14 KZN93006.1 - 0.017 14.4 0.0 6 6.1 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KZN93006.1 - 0.023 14.0 0.0 0.18 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain ADH_zinc_N PF00107.26 KZN93007.1 - 2e-24 86.0 0.6 3.7e-24 85.2 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KZN93007.1 - 1.3e-16 61.9 0.0 3.2e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KZN93007.1 - 1.7e-12 47.1 0.0 1e-11 44.7 0.0 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KZN93007.1 - 0.0053 17.0 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain Raffinose_syn PF05691.12 KZN93008.1 - 9.8e-50 169.1 1.2 8.5e-48 162.7 1.0 2.8 3 1 0 3 3 3 1 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.18 KZN93008.1 - 0.00017 20.7 0.2 0.0003 19.8 0.2 1.3 1 0 0 1 1 1 1 Melibiase tRNA-synt_1b PF00579.25 KZN93009.1 - 3.1e-71 240.1 0.0 4e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 KZN93009.1 - 2.3e-46 156.5 0.0 4.5e-46 155.5 0.0 1.5 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain MutS_V PF00488.21 KZN93010.1 - 1.4e-67 227.4 0.1 2.8e-67 226.4 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KZN93010.1 - 1.4e-40 139.6 0.0 3e-40 138.5 0.0 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KZN93010.1 - 9.7e-33 112.8 0.2 2.1e-32 111.7 0.0 1.7 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 KZN93010.1 - 6.9e-16 58.8 0.0 1.9e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KZN93010.1 - 3.2e-13 49.8 0.4 6.6e-13 48.8 0.4 1.6 1 0 0 1 1 1 1 MutS family domain IV Shugoshin_C PF07557.11 KZN93010.1 - 1.9 8.4 5.1 0.74 9.7 0.3 2.5 2 0 0 2 2 2 0 Shugoshin C terminus YqfD PF06898.11 KZN93011.1 - 0.42 9.4 4.5 0.53 9.1 4.5 1.1 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD AJAP1_PANP_C PF15298.6 KZN93011.1 - 0.7 10.1 5.1 0.32 11.2 1.3 2.1 2 0 0 2 2 2 0 AJAP1/PANP C-terminus Exotox-A_target PF09102.10 KZN93013.1 - 0.062 13.3 1.1 0.31 11.0 0.7 1.9 1 1 1 2 2 2 0 Exotoxin A, targeting DUF1990 PF09348.10 KZN93013.1 - 0.069 13.2 0.1 0.087 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1990) RelB PF04221.12 KZN93013.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.6 2 0 0 2 2 2 0 RelB antitoxin HTH_10 PF04967.12 KZN93014.1 - 0.16 11.8 0.1 0.36 10.7 0.1 1.6 1 0 0 1 1 1 0 HTH DNA binding domain Peptidase_M28 PF04389.17 KZN93016.1 - 2e-30 106.0 0.0 2.5e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Sulf_transp PF04143.14 KZN93017.1 - 1.7e-07 31.1 10.7 8.3e-06 25.6 1.6 3.3 3 0 0 3 3 3 3 Sulphur transport DUF350 PF03994.14 KZN93017.1 - 0.062 13.5 1.7 18 5.6 0.0 3.7 3 0 0 3 3 3 0 Domain of Unknown Function (DUF350) FAD_binding_4 PF01565.23 KZN93018.1 - 3e-26 91.8 1.3 5.9e-26 90.9 1.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KZN93018.1 - 2.3e-12 46.8 0.0 4.7e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like LigD_N PF13298.6 KZN93019.1 - 1.4e-36 125.0 0.0 2.3e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) ABC_tran PF00005.27 KZN93020.1 - 2.1e-47 161.1 0.0 9.8e-30 103.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KZN93020.1 - 1.1e-40 140.0 27.8 5.3e-27 95.1 9.2 3.0 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KZN93020.1 - 6.6e-10 38.8 0.0 0.022 14.2 0.0 4.4 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KZN93020.1 - 0.00042 20.4 0.0 0.087 12.9 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KZN93020.1 - 0.00049 20.5 0.8 0.18 12.2 0.1 3.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KZN93020.1 - 0.00074 19.8 0.0 2.1 8.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain T2SSE PF00437.20 KZN93020.1 - 0.0014 17.7 0.0 0.26 10.3 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KZN93020.1 - 0.0021 18.0 0.2 3 7.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 KZN93020.1 - 0.0026 17.9 0.7 0.82 9.7 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_29 PF13555.6 KZN93020.1 - 0.0029 17.3 0.5 1.7 8.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF2075 PF09848.9 KZN93020.1 - 0.016 14.5 0.3 0.19 10.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 KZN93020.1 - 0.054 14.0 0.0 6.6 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KZN93020.1 - 0.06 12.9 0.0 4.5 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KZN93020.1 - 0.11 12.2 0.0 1.3 8.7 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_21 PF13304.6 KZN93020.1 - 0.13 12.0 0.2 15 5.3 0.0 3.3 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Pex14_N PF04695.13 KZN93020.1 - 0.75 10.4 2.3 7.6 7.2 0.0 3.2 4 0 0 4 4 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region tRNA-synt_2 PF00152.20 KZN93021.1 - 1.5e-87 293.6 0.0 1.2e-50 172.4 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KZN93021.1 - 1.7e-05 24.7 0.0 3.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain TauD PF02668.16 KZN93021.1 - 0.075 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family Cutinase PF01083.22 KZN93022.1 - 4.7e-43 147.2 0.8 6.2e-43 146.8 0.8 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KZN93022.1 - 0.0029 17.2 0.1 0.0047 16.5 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.16 KZN93022.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase VirJ PF06057.11 KZN93022.1 - 0.052 13.4 0.0 0.085 12.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Thioesterase PF00975.20 KZN93022.1 - 0.18 11.9 0.0 0.27 11.3 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain UbiA PF01040.18 KZN93023.1 - 1.9e-55 187.9 16.4 1.9e-55 187.9 16.4 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family PQ-loop PF04193.14 KZN93024.1 - 5.1e-22 77.4 6.0 9.6e-11 41.3 1.2 2.9 3 0 0 3 3 3 2 PQ loop repeat DoxX_3 PF13781.6 KZN93024.1 - 0.026 15.1 1.0 0.026 15.1 1.0 2.0 2 0 0 2 2 2 0 DoxX-like family Med8 PF10232.9 KZN93025.1 - 1.1e-63 214.9 0.1 1.2e-63 214.8 0.1 1.0 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Myc_N PF01056.18 KZN93025.1 - 0.033 14.1 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region TMEM154 PF15102.6 KZN93026.1 - 0.023 14.6 0.1 0.073 13.0 0.0 1.8 2 0 0 2 2 2 0 TMEM154 protein family EphA2_TM PF14575.6 KZN93026.1 - 0.026 15.4 1.1 0.097 13.6 1.1 2.0 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RCR PF12273.8 KZN93026.1 - 0.22 12.2 9.0 1 10.0 9.0 1.9 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DctM PF06808.12 KZN93027.1 - 0.045 12.6 0.7 0.06 12.2 0.7 1.1 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporter, DctM component DUF4808 PF16066.5 KZN93027.1 - 0.72 10.4 2.5 2.7 8.6 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4808) PMI_typeI PF01238.21 KZN93028.1 - 5.4e-59 200.3 0.1 2.5e-57 194.8 0.1 2.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 KZN93028.1 - 0.0056 16.4 0.0 0.36 10.6 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Glyco_hydro_92 PF07971.12 KZN93031.1 - 2.8e-147 491.4 0.5 3.4e-147 491.1 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KZN93031.1 - 5e-63 213.2 0.5 5e-63 213.2 0.5 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 92 N-terminal domain Bac_rhamnosid6H PF17389.2 KZN93032.1 - 4.8e-10 39.2 0.0 9.9e-10 38.2 0.0 1.6 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_2_N PF02837.18 KZN93032.1 - 0.0027 17.6 0.1 0.0054 16.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Bac_rhamnosid_N PF08531.10 KZN93032.1 - 0.039 13.8 0.0 0.091 12.6 0.0 1.6 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain Glyco_hydro_36 PF17167.4 KZN93032.1 - 0.09 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain LEA_2 PF03168.13 KZN93032.1 - 0.13 12.8 0.0 11 6.6 0.0 3.1 3 0 0 3 3 3 0 Late embryogenesis abundant protein Sugar_tr PF00083.24 KZN93033.1 - 1.8e-65 221.6 28.1 2.3e-64 218.0 28.1 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN93033.1 - 1.2e-16 60.6 31.3 8.3e-09 34.8 12.8 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KZN93033.1 - 3.8e-06 25.6 9.2 0.0024 16.3 5.2 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Tetraspanin PF00335.20 KZN93033.1 - 0.33 10.6 9.3 0.037 13.7 4.4 2.0 2 0 0 2 2 2 0 Tetraspanin family Glyco_hydro_79C PF16862.5 KZN93034.1 - 4.5e-24 85.3 2.8 4.5e-24 85.3 2.8 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain Glyco_hydro_127 PF07944.12 KZN93035.1 - 1.2e-134 449.6 0.2 1.4e-134 449.5 0.2 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 DUF4986 PF16375.5 KZN93035.1 - 0.014 16.0 0.0 0.036 14.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function 4HBT PF03061.22 KZN93036.1 - 1.2e-11 44.8 0.0 2.2e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily APS_kinase PF01583.20 KZN93037.1 - 1.1e-72 243.1 0.0 1.3e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KZN93037.1 - 5.8e-07 29.8 0.0 1.2e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KZN93037.1 - 2.4e-05 24.9 0.0 4.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KZN93037.1 - 0.00081 19.8 0.0 0.00081 19.8 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 KZN93037.1 - 0.0091 15.5 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 KZN93037.1 - 0.054 12.8 0.0 0.1 11.9 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin Hpr_kinase_C PF07475.12 KZN93037.1 - 0.07 12.6 0.0 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain PEPCK_ATP PF01293.20 KZN93037.1 - 0.08 11.6 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_29 PF13555.6 KZN93037.1 - 0.088 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KZN93037.1 - 0.1 12.9 0.0 0.37 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 KZN93037.1 - 0.12 11.6 0.1 0.22 10.6 0.1 1.4 1 1 0 1 1 1 0 G-protein alpha subunit AAA_24 PF13479.6 KZN93037.1 - 0.17 11.6 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain V-ATPase_C PF03223.15 KZN93038.1 - 4.4e-128 427.8 0.1 5e-128 427.6 0.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C NMT PF01233.19 KZN93038.1 - 0.038 13.8 0.4 0.073 12.9 0.4 1.4 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain mRNA_cap_C PF03919.15 KZN93038.1 - 0.1 13.3 0.1 0.26 11.9 0.1 1.7 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain RhoGAP PF00620.27 KZN93039.1 - 2.3e-46 157.4 0.8 4.5e-46 156.4 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 KZN93039.1 - 5.4e-15 55.4 19.6 7.1e-10 39.0 2.5 2.4 2 0 0 2 2 2 2 LIM domain CENP-H PF05837.12 KZN93039.1 - 0.009 16.4 3.6 0.009 16.4 3.6 2.8 2 0 0 2 2 2 1 Centromere protein H (CENP-H) bZIP_Maf PF03131.17 KZN93039.1 - 0.12 13.0 8.1 0.2 12.2 2.3 2.6 2 0 0 2 2 2 0 bZIP Maf transcription factor 5_nucleotid PF05761.14 KZN93039.1 - 0.15 10.9 1.9 0.27 10.1 1.9 1.3 1 0 0 1 1 1 0 5' nucleotidase family CENP-F_leu_zip PF10473.9 KZN93039.1 - 0.36 10.8 16.8 0.073 13.1 5.4 3.5 4 0 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlgN PF05130.12 KZN93039.1 - 0.4 11.2 9.3 0.2 12.2 5.4 2.1 2 0 0 2 2 2 0 FlgN protein DUF4407 PF14362.6 KZN93039.1 - 2 7.7 5.1 3.8 6.8 5.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 KZN93039.1 - 3 7.9 10.3 0.22 11.6 4.9 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4164 PF13747.6 KZN93039.1 - 3 8.2 14.0 0.19 12.0 4.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) KLRAQ PF10205.9 KZN93039.1 - 3.1 8.1 12.1 0.095 12.9 3.2 2.9 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein FKBP_C PF00254.28 KZN93041.1 - 8.6e-29 99.7 0.0 1e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase AP_endonuc_2 PF01261.24 KZN93042.1 - 1.3e-30 106.4 0.0 1.7e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel GFO_IDH_MocA PF01408.22 KZN93043.1 - 1.1e-24 87.6 0.0 1.5e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KZN93043.1 - 8e-16 58.1 0.0 1.6e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain CoA_binding_2 PF13380.6 KZN93043.1 - 0.025 15.1 0.0 0.048 14.1 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain Semialdhyde_dh PF01118.24 KZN93043.1 - 0.035 14.6 0.0 0.063 13.7 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Sugar_tr PF00083.24 KZN93044.1 - 4.8e-137 457.5 21.8 5.5e-137 457.3 21.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN93044.1 - 5.5e-23 81.4 42.1 1.3e-22 80.2 33.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily RhodobacterPufX PF11511.8 KZN93044.1 - 0.19 11.4 1.0 28 4.4 0.0 3.0 2 0 0 2 2 2 0 Intrinsic membrane protein PufX APH PF01636.23 KZN93045.1 - 1.5e-11 44.7 0.7 6.8e-10 39.3 0.7 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN93045.1 - 0.00013 21.6 0.1 0.00038 20.1 0.1 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase HMG_box_2 PF09011.10 KZN93045.1 - 0.16 12.6 0.0 0.39 11.4 0.0 1.5 1 0 0 1 1 1 0 HMG-box domain FeS_assembly_P PF01883.19 KZN93045.1 - 0.17 12.1 0.0 2.2 8.5 0.0 2.2 1 1 1 2 2 2 0 Iron-sulfur cluster assembly protein Shikimate_dh_N PF08501.11 KZN93046.1 - 1e-20 73.8 0.0 2.4e-20 72.6 0.0 1.7 1 1 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KZN93046.1 - 0.00033 20.4 0.1 0.00083 19.1 0.1 1.8 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KZN93046.1 - 0.15 12.1 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Inositol_P PF00459.25 KZN93047.1 - 9.3e-82 274.6 0.0 1.1e-81 274.4 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family APH PF01636.23 KZN93048.1 - 1.6e-08 34.8 3.3 3e-08 33.9 2.5 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN93048.1 - 0.033 13.8 0.0 0.088 12.4 0.0 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase DHquinase_I PF01487.15 KZN93049.1 - 4.1e-35 122.1 0.0 5.6e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KZN93049.1 - 1.3e-19 70.9 0.1 4.5e-19 69.1 0.0 1.8 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KZN93049.1 - 3.1e-18 65.8 0.0 9.5e-18 64.2 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KZN93049.1 - 3.1e-10 39.6 0.1 5.8e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KZN93049.1 - 2.8e-06 27.4 0.1 7.7e-06 26.0 0.1 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.6 KZN93049.1 - 0.055 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.18 KZN93050.1 - 6e-22 77.9 0.0 9.8e-22 77.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN93050.1 - 8.6e-07 29.0 17.4 1.3e-06 28.4 17.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_II PF01220.19 KZN93051.1 - 7.1e-63 210.4 0.1 8.2e-63 210.2 0.1 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Sortilin-Vps10 PF15902.5 KZN93051.1 - 0.15 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Sortilin, neurotensin receptor 3, Arrestin_C PF02752.22 KZN93052.1 - 7.9e-05 23.1 0.0 0.49 10.8 0.1 2.4 1 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 KZN93052.1 - 0.016 14.9 0.1 0.034 13.8 0.0 1.6 2 0 0 2 2 2 0 Arrestin_N terminal like Arrestin_N PF00339.29 KZN93052.1 - 0.066 13.3 0.1 0.29 11.2 0.0 2.2 3 0 0 3 3 3 0 Arrestin (or S-antigen), N-terminal domain Fungal_trans_2 PF11951.8 KZN93053.1 - 9.3e-33 113.6 9.4 3.5e-32 111.7 9.4 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN93053.1 - 1.9e-06 27.9 9.3 5.1e-06 26.5 9.3 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Choline_kinase PF01633.20 KZN93054.1 - 4.4e-42 144.1 0.0 1.4e-40 139.2 0.0 2.2 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 KZN93054.1 - 4.6e-08 33.3 0.1 9.4e-08 32.3 0.1 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family CHORD PF04968.12 KZN93055.1 - 3.7e-46 155.7 18.5 2.6e-27 95.3 5.6 3.0 2 1 0 2 2 2 2 CHORD CS PF04969.16 KZN93055.1 - 3.7e-14 53.5 0.0 5.8e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 CS domain DUF836 PF05768.14 KZN93056.1 - 8e-14 51.8 0.0 9.7e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 KZN93056.1 - 0.011 15.9 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin Methyltransf_31 PF13847.6 KZN93058.1 - 8.2e-29 100.4 0.0 1.2e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN93058.1 - 3.2e-20 72.6 0.0 7e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN93058.1 - 5.7e-18 65.4 0.0 1.4e-17 64.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KZN93058.1 - 2.5e-16 59.7 0.0 5.3e-16 58.7 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KZN93058.1 - 1.4e-10 41.2 0.0 3.9e-10 39.8 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KZN93058.1 - 4.3e-09 36.4 0.1 7.7e-09 35.6 0.1 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KZN93058.1 - 4.6e-09 36.1 0.1 1e-08 35.0 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 KZN93058.1 - 1.1e-06 29.2 0.0 2.2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KZN93058.1 - 4.1e-05 23.0 0.0 5.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KZN93058.1 - 6.6e-05 22.5 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.18 KZN93058.1 - 0.00054 19.7 0.0 0.00089 19.0 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 CMAS PF02353.20 KZN93058.1 - 0.0011 18.3 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DOT1 PF08123.13 KZN93058.1 - 0.0013 18.3 0.1 0.0038 16.8 0.1 1.9 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_32 PF13679.6 KZN93058.1 - 0.0018 18.3 0.0 0.0038 17.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KZN93058.1 - 0.0049 16.1 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 2 NNMT/PNMT/TEMT family Methyltransf_16 PF10294.9 KZN93058.1 - 0.0054 16.5 0.0 0.009 15.8 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_3 PF01596.17 KZN93058.1 - 0.014 14.6 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_8 PF05148.15 KZN93058.1 - 0.045 13.6 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_4 PF02390.17 KZN93058.1 - 0.046 13.2 0.0 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_15 PF09445.10 KZN93058.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 KZN93058.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain FtsJ PF01728.19 KZN93058.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase SBF PF01758.16 KZN93059.1 - 1e-49 168.9 10.6 1e-49 168.9 10.6 2.5 2 2 1 3 3 3 1 Sodium Bile acid symporter family FA_hydroxylase PF04116.13 KZN93059.1 - 8.2 6.8 8.7 0.6 10.5 0.2 2.9 1 1 0 2 2 2 0 Fatty acid hydroxylase superfamily Rhodanese PF00581.20 KZN93060.1 - 8.4e-08 32.7 0.0 1.1e-07 32.4 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DUF3425 PF11905.8 KZN93061.1 - 1.1e-15 57.7 0.0 1.9e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KZN93061.1 - 0.18 11.9 9.8 0.44 10.7 9.8 1.6 1 0 0 1 1 1 0 bZIP transcription factor adh_short PF00106.25 KZN93062.1 - 7.5e-21 74.5 0.0 1.3e-19 70.4 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN93062.1 - 1.4e-16 60.8 0.0 1e-15 58.0 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN93062.1 - 0.0019 18.1 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KZN93062.1 - 0.062 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 14-3-3 PF00244.20 KZN93065.1 - 3.2e-09 36.6 0.1 5.3e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 14-3-3 protein Toxin_15 PF07906.13 KZN93065.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 ShET2 enterotoxin, N-terminal region Metallophos PF00149.28 KZN93066.1 - 2.1e-11 44.7 0.4 3.6e-11 43.9 0.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Sugar_tr PF00083.24 KZN93067.1 - 4.4e-82 276.3 23.6 5.1e-82 276.1 23.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN93067.1 - 2.5e-30 105.6 24.9 2.5e-30 105.6 24.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KZN93067.1 - 0.011 14.2 6.1 0.0074 14.8 2.8 2.0 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KZN93067.1 - 0.02 13.3 6.2 0.3 9.4 1.2 2.9 2 1 1 3 3 3 0 Transmembrane secretion effector GMC_oxred_N PF00732.19 KZN93068.1 - 5.3e-46 157.3 0.3 3.2e-45 154.8 0.3 1.9 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KZN93068.1 - 8.8e-30 104.1 0.0 1.4e-29 103.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KZN93068.1 - 1.3e-06 27.7 1.9 0.016 14.3 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KZN93068.1 - 2.8e-05 24.3 0.1 7.1e-05 23.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KZN93068.1 - 3.8e-05 23.5 7.5 0.00032 20.4 7.5 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KZN93068.1 - 0.00051 19.2 0.1 0.00076 18.6 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KZN93068.1 - 0.0051 16.1 0.4 0.043 13.1 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KZN93068.1 - 0.013 14.8 0.3 0.023 13.9 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KZN93068.1 - 0.022 13.5 0.1 0.037 12.7 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 KZN93068.1 - 0.99 9.4 2.9 1.9 8.5 0.2 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding Asp4 PF16996.5 KZN93069.1 - 9.6 6.1 7.7 5.6 6.8 0.2 2.5 2 0 0 2 2 2 0 Accessory secretory protein Sec Asp4 APH PF01636.23 KZN93071.1 - 5e-09 36.4 0.0 2e-08 34.5 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN93071.1 - 0.0082 15.7 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Transferase PF02458.15 KZN93072.1 - 1.9e-14 53.2 0.0 2.5e-09 36.3 0.0 2.0 2 0 0 2 2 2 2 Transferase family ketoacyl-synt PF00109.26 KZN93073.1 - 4.8e-76 255.7 0.0 1.3e-75 254.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KZN93073.1 - 1e-60 206.0 0.2 1.5e-60 205.4 0.2 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KZN93073.1 - 7e-49 166.2 0.0 1.7e-48 164.9 0.0 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KZN93073.1 - 7e-48 163.4 0.0 1.1e-47 162.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KZN93073.1 - 1.4e-38 131.5 0.0 6.6e-38 129.4 0.0 2.3 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KZN93073.1 - 2.4e-20 73.1 0.0 1e-19 71.1 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain adh_short PF00106.25 KZN93073.1 - 6.4e-17 61.7 0.6 5.4e-16 58.6 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase KAsynt_C_assoc PF16197.5 KZN93073.1 - 1.1e-16 61.3 0.0 2.7e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KZN93073.1 - 1.1e-13 51.7 0.0 4.1e-12 46.6 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N PF00107.26 KZN93073.1 - 1.7e-13 50.6 0.1 9.2e-13 48.3 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KZN93073.1 - 2.5e-11 44.7 0.0 4.2e-09 37.5 0.0 3.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 KZN93073.1 - 9.9e-11 41.7 0.0 2.1e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN93073.1 - 1.1e-10 42.0 0.0 4e-10 40.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN93073.1 - 1.8e-08 34.3 0.0 2.3e-07 30.8 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain PP-binding PF00550.25 KZN93073.1 - 1.3e-07 31.9 0.1 4.1e-07 30.2 0.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KZN93073.1 - 1e-06 28.3 0.1 2.4e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 KZN93073.1 - 3.7e-06 26.4 0.0 8.2e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 KZN93073.1 - 4.8e-06 26.3 0.0 1.4e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 KZN93073.1 - 4.9e-06 26.4 0.1 1.2e-05 25.1 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SAT PF16073.5 KZN93073.1 - 0.0011 18.7 0.9 0.0049 16.6 0.9 2.0 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Polysacc_synt_2 PF02719.15 KZN93073.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ACP_syn_III PF08545.10 KZN93073.1 - 0.058 13.2 1.7 0.7 9.8 1.7 2.5 1 1 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NAD_binding_10 PF13460.6 KZN93073.1 - 0.093 12.6 1.6 3.8 7.4 0.7 2.6 2 0 0 2 2 2 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KZN93073.1 - 0.2 11.1 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase FSH1 PF03959.13 KZN93074.1 - 8.3e-27 94.2 0.0 5.9e-26 91.4 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) EMP24_GP25L PF01105.24 KZN93075.1 - 9.5e-50 169.1 0.4 1.1e-49 168.9 0.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Filament PF00038.21 KZN93076.1 - 0.0027 17.4 7.1 0.0027 17.4 7.1 4.6 1 1 3 4 4 4 2 Intermediate filament protein PAM2 PF07145.15 KZN93076.1 - 0.17 11.7 13.1 0.33 10.7 0.0 4.3 4 0 0 4 4 4 0 Ataxin-2 C-terminal region Glyco_hydro_17 PF00332.18 KZN93077.1 - 2.1e-40 139.3 0.1 1e-39 137.0 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 GLE1 PF07817.13 KZN93078.1 - 7.4e-54 182.6 0.0 1.2e-53 181.9 0.0 1.3 1 0 0 1 1 1 1 GLE1-like protein Hid1 PF12722.7 KZN93078.1 - 0.95 7.5 19.8 1.2 7.1 19.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SOBP PF15279.6 KZN93078.1 - 5.2 7.6 8.2 9.5 6.7 8.2 1.5 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4045 PF13254.6 KZN93078.1 - 5.7 6.5 28.4 8 6.0 28.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Nop53 PF07767.11 KZN93078.1 - 8.7 5.6 49.0 13 5.0 49.0 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RNB PF00773.19 KZN93079.1 - 8e-87 291.6 0.2 1.6e-86 290.6 0.0 1.6 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 KZN93079.1 - 6.9e-26 90.1 0.0 1.8e-25 88.8 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 KZN93079.1 - 1.5e-25 89.4 0.0 4.6e-25 87.8 0.0 1.9 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 KZN93079.1 - 0.00019 21.5 0.0 0.019 15.1 0.0 2.7 2 0 0 2 2 2 1 Cold shock domain Rrp44_CSD1 PF17216.3 KZN93079.1 - 0.00025 20.8 0.0 0.00058 19.6 0.0 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain UQ_con PF00179.26 KZN93080.1 - 1.3e-35 122.1 0.0 1.9e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KZN93080.1 - 0.0016 18.1 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KZN93080.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 RWD domain Apt1 PF10351.9 KZN93081.1 - 3.5 6.4 8.2 3.6 6.3 8.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 KZN93081.1 - 4.7 5.6 9.1 4.5 5.7 9.1 1.1 1 0 0 1 1 1 0 Macoilin family MMgT PF10270.9 KZN93082.1 - 2.5e-35 120.8 0.0 2.9e-35 120.6 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter EF1_GNE PF00736.19 KZN93084.1 - 1.8e-32 111.4 0.9 1.8e-32 111.4 0.9 1.7 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KZN93084.1 - 4.2e-11 43.1 1.8 4.2e-11 43.1 1.8 3.0 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 KZN93084.1 - 0.00031 20.9 0.2 0.00064 19.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KZN93084.1 - 0.00049 20.3 0.8 0.0017 18.5 0.1 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KZN93084.1 - 0.052 13.6 0.2 0.7 10.0 0.2 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AAA_2 PF07724.14 KZN93085.1 - 5.2e-45 153.6 0.0 5e-44 150.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KZN93085.1 - 1.3e-35 121.5 1.5 1.3e-35 121.5 1.5 2.6 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KZN93085.1 - 8.3e-27 93.1 0.2 2.4e-26 91.6 0.2 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KZN93085.1 - 2.3e-19 70.1 0.0 1.1e-10 42.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KZN93085.1 - 3.2e-12 46.6 0.0 6.8e-08 32.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KZN93085.1 - 2.3e-08 34.6 10.9 0.00035 21.0 0.6 4.4 3 2 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KZN93085.1 - 1.8e-07 31.5 5.5 0.0097 16.2 0.1 4.2 3 3 1 4 4 4 2 AAA domain Sigma54_activat PF00158.26 KZN93085.1 - 8.3e-07 28.9 0.6 0.00023 20.9 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 KZN93085.1 - 3.5e-06 26.6 0.1 0.0068 15.8 0.0 3.7 4 1 0 4 4 2 1 Bacterial TniB protein AAA_14 PF13173.6 KZN93085.1 - 3.7e-06 27.0 0.2 0.041 13.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain ATPase_2 PF01637.18 KZN93085.1 - 5.6e-06 26.4 3.2 1.4 8.8 0.0 4.5 3 3 2 5 5 4 2 ATPase domain predominantly from Archaea NACHT PF05729.12 KZN93085.1 - 8e-06 25.9 0.0 0.11 12.5 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_7 PF12775.7 KZN93085.1 - 1.2e-05 24.9 0.0 0.025 14.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_28 PF13521.6 KZN93085.1 - 7.3e-05 23.1 0.8 0.033 14.4 0.0 3.5 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 KZN93085.1 - 9.1e-05 22.3 0.0 0.55 9.9 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_24 PF13479.6 KZN93085.1 - 0.00014 21.6 0.1 0.14 11.8 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 KZN93085.1 - 0.00024 21.7 1.2 0.8 10.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain SRP54 PF00448.22 KZN93085.1 - 0.00038 20.2 0.1 0.063 12.9 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ResIII PF04851.15 KZN93085.1 - 0.00061 19.8 0.0 2.6 8.0 0.0 3.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KZN93085.1 - 0.0011 19.3 0.4 0.15 12.4 0.1 3.2 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KZN93085.1 - 0.0013 19.1 0.0 0.86 10.0 0.0 2.8 2 1 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 KZN93085.1 - 0.0019 17.8 0.1 0.035 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KZN93085.1 - 0.0025 17.2 0.1 2.5 7.4 0.1 3.0 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI TrwB_AAD_bind PF10412.9 KZN93085.1 - 0.0033 16.4 0.1 0.37 9.6 0.0 2.5 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 KZN93085.1 - 0.0035 17.1 2.1 0.13 12.0 0.0 3.5 4 0 0 4 4 3 1 AAA domain TsaE PF02367.17 KZN93085.1 - 0.0039 17.2 0.1 2.6 8.1 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KZN93085.1 - 0.0091 16.2 0.0 5.9 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KZN93085.1 - 0.0093 15.9 0.0 3.1 7.7 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase DUF815 PF05673.13 KZN93085.1 - 0.0093 15.1 0.6 0.35 10.0 0.2 3.1 3 1 0 3 3 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 KZN93085.1 - 0.0094 16.5 1.7 2 8.9 0.0 3.3 3 0 0 3 3 3 1 ABC transporter Roc PF08477.13 KZN93085.1 - 0.011 16.0 0.1 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 KZN93085.1 - 0.013 15.3 0.0 0.48 10.2 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.12 KZN93085.1 - 0.017 14.4 0.0 1.9 7.8 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin ATP_bind_1 PF03029.17 KZN93085.1 - 0.027 14.3 0.1 0.51 10.1 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 KZN93085.1 - 0.041 13.8 0.1 0.53 10.2 0.0 2.6 2 0 0 2 2 2 0 NTPase AAA_6 PF12774.7 KZN93085.1 - 0.043 12.8 0.1 4 6.3 0.0 2.9 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region AAA_21 PF13304.6 KZN93085.1 - 0.063 13.1 3.7 0.9 9.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF853 PF05872.12 KZN93085.1 - 0.083 11.5 0.0 0.083 11.5 0.0 2.5 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF853) DNA_pol3_delta2 PF13177.6 KZN93085.1 - 0.1 12.4 0.1 2.5 7.8 0.0 2.7 2 0 0 2 2 2 0 DNA polymerase III, delta subunit UvrD-helicase PF00580.21 KZN93085.1 - 0.16 11.5 4.1 0.36 10.3 0.1 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Cytochrom_C552 PF02335.15 KZN93085.1 - 0.38 9.6 1.1 0.59 9.0 1.1 1.2 1 0 0 1 1 1 0 Cytochrome c552 GrpE PF01025.19 KZN93085.1 - 1.5 8.5 7.8 4.4 6.9 7.8 1.9 1 0 0 1 1 1 0 GrpE Endonuc_Holl PF10107.9 KZN93085.1 - 1.7 8.5 7.0 5.6 6.8 0.1 3.1 4 0 0 4 4 2 0 Endonuclease related to archaeal Holliday junction resolvase DUF4407 PF14362.6 KZN93085.1 - 3.6 6.8 11.3 6.7 6.0 11.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 KZN93085.1 - 4.5 7.1 11.0 8 6.3 5.9 2.7 1 1 1 2 2 2 0 Septum formation initiator MutS_V PF00488.21 KZN93086.1 - 2.4e-50 171.2 0.0 3.7e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KZN93086.1 - 5.1e-15 56.2 0.0 1e-14 55.2 0.0 1.5 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 KZN93086.1 - 0.032 14.6 0.0 0.077 13.4 0.0 1.6 1 0 0 1 1 1 0 MutS family domain IV T2SSE PF00437.20 KZN93086.1 - 0.044 12.8 0.0 0.082 11.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 KZN93086.1 - 0.046 14.2 0.0 0.18 12.2 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KZN93086.1 - 0.15 12.1 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 KZN93087.1 - 1.7e-43 148.9 0.0 2.4e-43 148.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN93087.1 - 2.5e-18 66.3 0.0 3.7e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase REJ PF02010.15 KZN93087.1 - 0.00093 18.1 0.6 0.0014 17.5 0.6 1.2 1 0 0 1 1 1 1 REJ domain Kinase-like PF14531.6 KZN93087.1 - 0.0028 17.0 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KZN93087.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sas10 PF09368.10 KZN93088.1 - 5.4e-28 97.3 10.2 5.4e-28 97.3 10.2 2.7 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KZN93088.1 - 1.8e-14 54.1 1.3 1.9e-13 50.8 0.0 2.9 2 0 0 2 2 2 1 Sas10/Utp3/C1D family adh_short PF00106.25 KZN93089.1 - 3.6e-26 91.8 0.0 5e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN93089.1 - 8.4e-15 55.0 0.0 1.9e-14 53.8 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN93089.1 - 4.5e-08 33.2 0.1 8.7e-08 32.3 0.1 1.5 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KZN93089.1 - 1.6e-05 24.4 0.1 8.7e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KZN93089.1 - 0.00077 19.0 0.1 0.0024 17.4 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KZN93089.1 - 0.0022 17.3 0.3 0.0037 16.6 0.3 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 KZN93089.1 - 0.0079 16.6 0.4 0.017 15.5 0.4 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 KZN93089.1 - 0.011 15.8 0.7 0.023 14.8 0.4 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Phage_glycop_gL PF11108.8 KZN93089.1 - 0.039 14.0 0.0 0.084 12.9 0.0 1.6 1 1 0 1 1 1 0 Viral glycoprotein L NAD_binding_2 PF03446.15 KZN93089.1 - 0.042 14.0 0.1 0.08 13.1 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_3 PF13738.6 KZN93089.1 - 0.08 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Disulph_isomer PF06491.11 KZN93089.1 - 0.14 12.3 0.0 0.37 10.9 0.0 1.7 1 1 0 1 1 1 0 Disulphide isomerase FA_hydroxylase PF04116.13 KZN93090.1 - 5.1e-19 68.9 8.2 5.1e-19 68.9 8.2 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribosomal_L6e PF01159.19 KZN93091.1 - 1e-39 135.5 0.3 1.7e-39 134.8 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e AGP PF06376.12 KZN93091.1 - 0.014 15.2 0.2 0.14 12.0 0.3 2.4 2 0 0 2 2 2 0 Arabinogalactan peptide Proteasom_Rpn13 PF04683.13 KZN93092.1 - 1.3e-27 96.1 0.0 2e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 KZN93092.1 - 4e-12 46.3 4.6 4.6e-11 42.9 4.6 2.2 1 1 0 1 1 1 1 UCH-binding domain Ion_trans PF00520.31 KZN93093.1 - 5.8e-126 418.7 80.0 1.7e-42 145.4 7.1 4.8 4 1 0 4 4 4 4 Ion transport protein GPHH PF16905.5 KZN93093.1 - 0.0004 20.1 0.0 0.00093 18.9 0.0 1.6 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_1 PF00036.32 KZN93093.1 - 0.0066 15.9 0.0 0.026 14.1 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KZN93093.1 - 0.035 14.0 0.0 0.19 11.7 0.0 2.4 1 0 0 1 1 1 0 EF-hand domain PKD_channel PF08016.12 KZN93093.1 - 0.91 8.1 60.6 0.19 10.4 12.5 7.1 5 2 2 7 7 7 0 Polycystin cation channel Codanin-1_C PF15296.6 KZN93094.1 - 0.16 12.0 0.7 0.23 11.6 0.7 1.2 1 0 0 1 1 1 0 Codanin-1 C-terminus DUF3558 PF12079.8 KZN93094.1 - 3.7 7.5 11.9 1.7 8.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3558) SET PF00856.28 KZN93095.1 - 5.2e-17 62.7 0.1 1.3e-16 61.5 0.1 1.7 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 KZN93095.1 - 4.2e-11 43.5 10.9 4.4e-11 43.4 4.7 2.4 2 0 0 2 2 2 1 Pre-SET motif Pkinase PF00069.25 KZN93096.1 - 1.1e-69 234.7 0.0 1.8e-69 234.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN93096.1 - 4.2e-40 137.7 0.0 8.3e-40 136.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KZN93096.1 - 6.3e-17 61.1 0.4 1.1e-16 60.3 0.4 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 KZN93096.1 - 6.2e-06 25.4 0.0 9.9e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KZN93096.1 - 1.2e-05 24.8 0.0 2.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KZN93096.1 - 7e-05 22.3 0.0 0.00074 18.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KZN93096.1 - 0.00086 19.3 0.0 0.0092 15.9 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.11 KZN93096.1 - 0.045 13.4 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.9 KZN93096.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 KZN93096.1 - 0.056 13.0 0.2 0.2 11.2 0.2 1.9 1 1 0 1 1 1 0 RIO1 family Grg1 PF11034.8 KZN93097.1 - 1.3e-29 102.2 14.5 1.5e-29 102.0 14.5 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 RSN1_7TM PF02714.15 KZN93098.1 - 3.3e-78 262.8 22.2 3.3e-78 262.8 22.2 1.6 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KZN93098.1 - 2.4e-43 147.6 1.6 2.4e-43 147.6 1.6 2.7 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KZN93098.1 - 1.4e-38 132.9 0.0 2e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter DUF3445 PF11927.8 KZN93100.1 - 9.8e-81 270.7 0.0 1.1e-80 270.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Homoserine_dh PF00742.19 KZN93101.1 - 3.4e-52 176.9 0.0 4.5e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KZN93101.1 - 6.9e-16 59.0 0.0 1.3e-15 58.1 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KZN93101.1 - 0.091 13.0 0.0 0.3 11.4 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DUF4078 PF13300.6 KZN93102.1 - 4.7e-28 97.3 8.4 4.7e-28 97.3 8.4 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) PRIMA1 PF16101.5 KZN93102.1 - 0.82 9.7 3.8 1.8 8.6 3.8 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 HMG_box PF00505.19 KZN93104.1 - 2.5e-25 88.7 0.3 2.5e-25 88.7 0.3 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KZN93104.1 - 5.6e-18 65.3 0.8 5.6e-18 65.3 0.8 1.9 2 1 1 3 3 3 1 HMG-box domain Ccdc124 PF06244.12 KZN93104.1 - 0.014 16.0 0.0 0.014 16.0 0.0 2.3 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 124 /Oxs1 YABBY PF04690.13 KZN93104.1 - 0.36 11.4 2.2 0.29 11.7 0.8 1.6 1 1 1 2 2 2 0 YABBY protein CENP-H PF05837.12 KZN93105.1 - 5.1e-31 107.4 14.3 3.7e-30 104.6 9.2 2.1 2 0 0 2 2 2 2 Centromere protein H (CENP-H) KIAA1430 PF13879.6 KZN93105.1 - 0.039 14.7 1.0 0.078 13.7 1.0 1.6 1 0 0 1 1 1 0 KIAA1430 homologue APC_N_CC PF16689.5 KZN93105.1 - 6.8 6.8 16.7 0.65 10.1 5.5 2.9 2 1 1 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain ATG11 PF10377.9 KZN93106.1 - 6.8e-45 152.3 0.0 6.8e-45 152.3 0.0 4.4 4 0 0 4 4 4 1 Autophagy-related protein 11 APG17 PF04108.12 KZN93106.1 - 4.2e-08 32.7 1.0 4.2e-06 26.1 1.3 6.0 4 2 2 6 6 6 2 Autophagy protein Apg17 ATG16 PF08614.11 KZN93106.1 - 0.0067 16.7 9.0 0.0067 16.7 9.0 6.9 4 2 2 6 6 6 3 Autophagy protein 16 (ATG16) Phage_TAC_12 PF12363.8 KZN93106.1 - 0.054 13.9 0.6 19 5.7 0.0 3.2 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC Baculo_PEP_C PF04513.12 KZN93106.1 - 1.3 9.0 16.8 5.4 7.1 0.1 6.6 5 2 3 8 8 8 0 Baculovirus polyhedron envelope protein, PEP, C terminus RPW8 PF05659.11 KZN93106.1 - 1.8 8.2 11.1 0.052 13.2 1.3 3.6 4 1 0 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF1664 PF07889.12 KZN93106.1 - 8.9 6.4 40.9 1.3 9.1 5.5 7.2 6 2 2 8 8 8 0 Protein of unknown function (DUF1664) Spb1_C PF07780.12 KZN93107.1 - 0.071 12.7 0.2 0.46 10.1 0.2 1.9 1 1 0 1 1 1 0 Spb1 C-terminal domain ATXN-1_C PF12547.8 KZN93107.1 - 0.12 12.8 1.6 0.22 11.9 1.6 1.4 1 0 0 1 1 1 0 Capicua transcriptional repressor modulator Abhydrolase_3 PF07859.13 KZN93109.1 - 6.4e-41 140.5 0.0 2.4e-39 135.4 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KZN93109.1 - 1.7e-07 30.4 0.0 6.9e-07 28.4 0.0 1.8 1 1 0 1 1 1 1 Steryl acetyl hydrolase HATPase_c PF02518.26 KZN93110.1 - 2.3e-31 108.6 0.0 7.7e-31 106.9 0.0 2.0 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KZN93110.1 - 2.6e-19 69.4 0.0 1e-18 67.6 0.0 2.1 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KZN93110.1 - 1.3e-18 66.8 0.0 5e-18 64.9 0.0 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 KZN93110.1 - 1.6e-12 47.9 0.0 4.4e-12 46.5 0.0 1.9 1 0 0 1 1 1 1 GAF domain AAA_16 PF13191.6 KZN93110.1 - 2.4e-10 41.1 0.0 2.1e-09 38.0 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain GAF PF01590.26 KZN93110.1 - 1.2e-08 35.6 0.0 3.1e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 KZN93110.1 - 9.7e-06 26.0 0.0 3.5e-05 24.1 0.0 2.0 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 KZN93110.1 - 6.3e-05 22.5 0.0 0.00027 20.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain NB-ARC PF00931.22 KZN93110.1 - 0.00083 18.6 1.4 0.9 8.7 0.5 3.1 3 0 0 3 3 3 2 NB-ARC domain HATPase_c_3 PF13589.6 KZN93110.1 - 0.0013 18.5 0.0 0.0034 17.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NACHT PF05729.12 KZN93110.1 - 0.0054 16.7 0.5 0.75 9.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_35 PF14516.6 KZN93110.1 - 0.02 13.7 0.0 0.23 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain DUF2514 PF10721.9 KZN93110.1 - 0.021 14.9 0.3 0.056 13.5 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Sugar_tr PF00083.24 KZN93112.1 - 2.2e-58 198.2 26.5 2.6e-58 198.0 26.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN93112.1 - 1.3e-25 90.1 27.3 1.7e-25 89.7 27.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hyd_65N_2 PF14498.6 KZN93113.1 - 1e-64 218.6 0.0 1.4e-64 218.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_1 PF00232.18 KZN93114.1 - 4e-145 483.7 0.9 6.6e-145 483.0 0.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 AAT PF03417.16 KZN93114.1 - 6.1e-19 68.6 0.0 1.1e-18 67.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Cytochrom_B561 PF03188.16 KZN93116.1 - 2.9e-16 59.8 5.3 2.9e-16 59.8 5.3 1.9 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 DUF4271 PF14093.6 KZN93116.1 - 0.0049 16.8 2.4 0.0068 16.3 2.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4271) DUF1129 PF06570.11 KZN93116.1 - 0.015 14.8 5.5 0.025 14.1 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) AgrB PF04647.15 KZN93116.1 - 0.3 10.4 8.5 0.6 9.4 6.6 1.9 1 1 1 2 2 2 0 Accessory gene regulator B DUF5090 PF17009.5 KZN93116.1 - 0.41 10.6 2.6 0.6 10.0 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) DUF4079 PF13301.6 KZN93116.1 - 0.68 10.1 17.4 1.3 9.2 1.4 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF4079) IncD PF17628.2 KZN93116.1 - 1.2 8.9 3.9 0.39 10.5 0.3 1.9 2 0 0 2 2 2 0 Inclusion membrane protein D DUF2427 PF10348.9 KZN93116.1 - 1.6 8.5 11.1 0.042 13.6 3.9 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF2427) tRNA-synt_2b PF00587.25 KZN93117.1 - 1.8e-19 70.4 0.0 2.8e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KZN93117.1 - 2.2e-09 37.5 2.2 8.5e-09 35.6 2.2 1.8 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain GOLGA2L5 PF15070.6 KZN93117.1 - 2.1e-06 26.7 1.2 2.8e-06 26.3 1.2 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 CENP-F_leu_zip PF10473.9 KZN93117.1 - 0.0012 18.9 1.9 0.29 11.1 0.0 2.2 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.15 KZN93117.1 - 0.0059 16.4 1.3 0.69 9.7 0.1 2.4 2 0 0 2 2 2 1 Septum formation initiator ZapB PF06005.12 KZN93117.1 - 0.0079 16.6 1.2 1.1 9.8 0.2 2.4 2 0 0 2 2 2 1 Cell division protein ZapB DUF4407 PF14362.6 KZN93117.1 - 0.081 12.3 5.4 0.032 13.6 2.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Jnk-SapK_ap_N PF09744.9 KZN93117.1 - 0.11 12.7 2.1 0.22 11.7 2.1 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 TMCO5 PF14992.6 KZN93117.1 - 0.17 11.5 2.0 0.25 10.9 2.0 1.2 1 0 0 1 1 1 0 TMCO5 family bZIP_1 PF00170.21 KZN93117.1 - 0.23 11.6 0.1 0.23 11.6 0.1 2.6 3 0 0 3 3 2 0 bZIP transcription factor E2F_CC-MB PF16421.5 KZN93117.1 - 0.52 10.7 2.9 2.5 8.5 0.3 2.4 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain PRKG1_interact PF15898.5 KZN93117.1 - 1.4 9.9 4.2 5.5 8.0 4.2 1.9 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF4200 PF13863.6 KZN93117.1 - 1.6 9.1 4.7 4.6 7.7 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Spc7 PF08317.11 KZN93117.1 - 2.8 6.7 6.8 6.5 5.5 6.9 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein Csm1_N PF18504.1 KZN93117.1 - 3 8.2 7.6 1.1 9.7 0.3 2.8 2 1 1 3 3 3 0 Csm1 N-terminal domain JIP_LZII PF16471.5 KZN93117.1 - 5.1 7.4 9.0 17 5.7 0.4 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II TMF_DNA_bd PF12329.8 KZN93117.1 - 8 6.5 7.6 5.3 7.1 5.1 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding BTB PF00651.31 KZN93118.1 - 0.0072 16.6 0.0 0.092 13.0 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain Y_phosphatase PF00102.27 KZN93119.1 - 2e-51 174.8 0.0 3.4e-51 174.1 0.0 1.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KZN93119.1 - 0.0058 16.8 0.0 0.015 15.4 0.0 1.7 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KZN93119.1 - 0.0062 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KZN93119.1 - 0.084 12.7 2.4 0.4 10.5 2.3 2.0 1 1 1 2 2 2 0 Dual specificity phosphatase, catalytic domain VanZ PF04892.12 KZN93120.1 - 1.2e-05 26.0 2.2 2.1e-05 25.2 2.2 1.4 1 1 0 1 1 1 1 VanZ like family Phage_holin_2_4 PF16082.5 KZN93120.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Bromodomain PF00439.25 KZN93121.1 - 4.5e-17 61.9 0.0 9.9e-17 60.8 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 KZN93121.1 - 2.8e-10 40.1 0.0 1e-09 38.3 0.0 2.0 1 0 0 1 1 1 1 Bromodomain associated Talin_middle PF09141.10 KZN93121.1 - 0.067 13.2 0.3 0.3 11.1 0.2 2.0 2 0 0 2 2 2 0 Talin, middle domain PBP1_TM PF14812.6 KZN93121.1 - 0.071 13.5 13.0 0.052 13.9 6.6 3.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HisKA_3 PF07730.13 KZN93121.1 - 0.48 11.0 4.5 1.8 9.1 0.0 3.3 3 0 0 3 3 3 0 Histidine kinase Piwi PF02171.17 KZN93122.1 - 4.6e-61 206.7 0.0 7.4e-61 206.0 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KZN93122.1 - 9.1e-13 49.0 0.0 3.7e-12 47.0 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KZN93122.1 - 9.4e-13 47.6 0.0 4.2e-12 45.5 0.0 2.1 2 0 0 2 2 2 1 Argonaute linker 1 domain PAZ PF02170.22 KZN93122.1 - 3.8e-11 42.9 0.7 7.6e-11 42.0 0.7 1.5 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 KZN93122.1 - 3.8e-11 43.1 0.0 9.4e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 KZN93122.1 - 1.1e-08 35.2 0.1 3.5e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 Argonaute linker 2 domain Suf PF05843.14 KZN93124.1 - 2.4e-92 310.1 0.0 2.4e-92 310.1 0.0 4.6 5 1 1 6 6 6 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KZN93124.1 - 3.1e-05 24.4 0.8 0.28 12.1 0.4 5.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KZN93124.1 - 0.0037 17.9 1.6 0.02 15.5 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat HAT PF02184.16 KZN93124.1 - 0.026 14.5 0.0 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat TPR_6 PF13174.6 KZN93124.1 - 0.13 13.0 0.6 3.6 8.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ASF1_hist_chap PF04729.13 KZN93125.1 - 8.1e-73 243.4 0.0 1.1e-72 243.0 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.12 KZN93125.1 - 0.0051 15.1 22.2 0.0068 14.7 22.2 1.0 1 0 0 1 1 1 1 Nop14-like family Lgl_C PF08596.10 KZN93126.1 - 9.4e-133 442.7 0.0 9.2e-132 439.4 0.0 2.1 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 KZN93126.1 - 9.6e-07 29.4 2.2 0.77 10.7 0.1 5.5 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN93126.1 - 5.3e-05 23.4 0.0 0.57 10.5 0.0 4.6 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain APH PF01636.23 KZN93127.1 - 1.8e-06 28.1 0.0 3.7e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family THUMP PF02926.17 KZN93128.1 - 1e-11 45.1 0.0 1.9e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 THUMP domain PAC1 PF16094.5 KZN93128.1 - 0.068 12.3 0.7 0.097 11.8 0.7 1.1 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Spot_14 PF07084.12 KZN93128.1 - 0.14 12.3 0.1 0.23 11.6 0.1 1.3 1 0 0 1 1 1 0 Thyroid hormone-inducible hepatic protein Spot 14 TPP_enzyme_N PF02776.18 KZN93129.1 - 3.1e-33 114.8 0.0 4.7e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KZN93129.1 - 7.6e-23 80.8 0.0 1.4e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KZN93129.1 - 7.7e-16 58.2 0.0 2.3e-15 56.7 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Pkinase PF00069.25 KZN93130.1 - 1.2e-60 205.2 0.0 1.9e-60 204.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN93130.1 - 5.4e-43 147.2 0.0 7.8e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KZN93130.1 - 7.1e-08 32.1 0.0 8.6e-07 28.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KZN93130.1 - 0.0054 15.6 1.6 0.0055 15.5 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KZN93130.1 - 0.018 14.4 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KZN93130.1 - 0.028 14.3 0.1 0.086 12.8 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Sec34 PF04136.15 KZN93131.1 - 1.5e-50 171.0 2.7 2.8e-50 170.1 2.7 1.5 1 0 0 1 1 1 1 Sec34-like family Exo70 PF03081.15 KZN93131.1 - 2.4 7.1 6.3 2.1 7.3 0.1 2.8 4 0 0 4 4 4 0 Exo70 exocyst complex subunit RCC1 PF00415.18 KZN93132.1 - 1.3e-30 105.7 3.3 2.4e-06 28.0 0.0 6.9 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KZN93132.1 - 3e-17 61.9 16.5 1.8e-12 46.7 0.2 6.3 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat Mcl1_mid PF12341.8 KZN93132.1 - 0.07 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region PUF PF00806.19 KZN93133.1 - 1.2e-13 49.9 0.0 0.26 11.1 0.0 7.6 9 0 0 9 9 9 5 Pumilio-family RNA binding repeat Pyridoxal_deC PF00282.19 KZN93134.1 - 3.6e-80 269.5 0.0 4e-79 266.1 0.0 2.3 2 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KZN93134.1 - 2.1e-06 27.0 0.0 3.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KZN93134.1 - 0.00016 21.1 0.0 0.00026 20.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Late_protein_L1 PF00500.18 KZN93134.1 - 0.079 11.8 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 L1 (late) protein SepSecS PF05889.13 KZN93134.1 - 0.17 10.5 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS RINT1_TIP1 PF04437.13 KZN93135.1 - 9.7e-182 605.3 0.1 9.7e-182 605.3 0.1 2.2 2 1 0 2 2 2 1 RINT-1 / TIP-1 family E2_bind PF08825.10 KZN93135.1 - 0.28 11.4 0.1 0.28 11.4 0.1 2.7 3 0 0 3 3 3 0 E2 binding domain TBCC_N PF16752.5 KZN93135.1 - 0.74 10.3 9.5 0.87 10.1 7.3 2.3 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain CRISPR_Cse2 PF09485.10 KZN93135.1 - 3 8.4 10.2 3.8 8.0 6.4 3.1 2 1 1 3 3 3 0 CRISPR-associated protein Cse2 (CRISPR_cse2) ABC_tran_Xtn PF12848.7 KZN93135.1 - 6.5 6.9 8.2 0.51 10.4 2.7 2.0 2 0 0 2 2 2 0 ABC transporter DNA_ligase_A_M PF01068.21 KZN93136.1 - 9.3e-53 178.9 0.1 6.8e-50 169.5 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KZN93136.1 - 3e-38 131.9 0.0 7.8e-38 130.5 0.0 1.8 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KZN93136.1 - 8.2e-19 68.0 0.0 2.5e-18 66.5 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KZN93136.1 - 0.00017 21.9 0.0 0.00032 21.0 0.0 1.4 1 0 0 1 1 1 1 RNA ligase DUF1365 PF07103.11 KZN93137.1 - 6.2e-28 98.1 0.0 8.5e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) Pyr_redox_2 PF07992.14 KZN93138.1 - 7.4e-12 45.1 0.0 5.7e-10 38.9 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN93138.1 - 6.9e-10 39.0 0.0 1.5e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KZN93138.1 - 1.4e-09 37.6 0.0 1.1e-07 31.4 0.0 3.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KZN93138.1 - 4.8e-08 31.9 0.1 1.3e-07 30.4 0.1 1.7 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KZN93138.1 - 2.9e-07 29.9 0.0 7.2e-06 25.4 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KZN93138.1 - 3.6e-06 26.8 0.0 1.3e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KZN93138.1 - 1.3e-05 25.2 0.0 0.00056 19.9 0.0 2.4 2 1 1 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 KZN93138.1 - 7.6e-05 22.1 0.0 0.0016 17.8 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Shikimate_DH PF01488.20 KZN93138.1 - 0.0055 16.8 0.0 1.4 8.9 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KZN93138.1 - 0.026 15.1 0.0 0.19 12.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KZN93138.1 - 0.2 10.7 0.0 0.44 9.6 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Whi5 PF08528.11 KZN93139.1 - 0.0072 15.9 0.4 0.014 15.0 0.4 1.5 1 0 0 1 1 1 1 Whi5 like Metallopep PF12044.8 KZN93140.1 - 2.5e-174 579.9 0.0 3.1e-174 579.6 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_5 PF13688.6 KZN93140.1 - 0.052 13.7 0.4 0.093 12.9 0.4 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KZN93140.1 - 0.12 12.9 0.2 0.25 11.8 0.2 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like CP2 PF04516.15 KZN93141.1 - 2.6e-80 269.0 0.0 4e-80 268.4 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor bZIP_2 PF07716.15 KZN93141.1 - 2.7 8.1 3.7 29 4.8 0.2 2.5 2 0 0 2 2 2 0 Basic region leucine zipper DUF3244 PF11589.8 KZN93142.1 - 5.4 7.2 7.2 27 4.9 7.2 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3244) Clathrin PF00637.20 KZN93143.1 - 2.7e-19 69.5 0.1 1.1e-18 67.5 0.1 2.0 3 0 0 3 3 3 1 Region in Clathrin and VPS WD40_like PF17005.5 KZN93143.1 - 0.053 12.8 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain HicB_lk_antitox PF15919.5 KZN93143.1 - 0.067 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system Vps39_1 PF10366.9 KZN93143.1 - 0.13 12.6 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 zf-RING_5 PF14634.6 KZN93143.1 - 0.24 11.4 0.2 0.47 10.5 0.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain PQQ_3 PF13570.6 KZN93143.1 - 0.38 11.3 1.7 1.7 9.3 0.2 2.8 3 0 0 3 3 3 0 PQQ-like domain Cwf_Cwc_15 PF04889.12 KZN93143.1 - 3 7.5 12.1 5.8 6.6 12.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF155 PF02582.14 KZN93144.1 - 1.3e-47 162.1 0.0 4.9e-47 160.3 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 Ribonuclease_T2 PF00445.18 KZN93145.1 - 2.8e-43 148.2 0.0 5.7e-43 147.3 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease T2 family zf-H2C2_2 PF13465.6 KZN93146.1 - 2.7e-08 33.9 3.6 0.0046 17.3 0.6 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KZN93146.1 - 3.9e-06 27.0 18.1 0.0035 17.7 4.5 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KZN93146.1 - 4.3e-06 26.6 4.8 0.019 14.9 3.1 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KZN93146.1 - 2.2e-05 24.9 17.1 0.0028 18.4 3.6 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KZN93146.1 - 0.0018 18.5 4.7 0.0035 17.6 2.3 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 KZN93146.1 - 0.47 10.9 3.0 1.4 9.4 3.0 1.8 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-BED PF02892.15 KZN93146.1 - 0.86 9.7 5.9 1.1 9.4 2.3 2.4 1 1 1 2 2 2 0 BED zinc finger ubiquitin PF00240.23 KZN93147.1 - 4.3e-34 116.1 0.6 7.9e-34 115.2 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 KZN93147.1 - 1.2e-26 92.6 1.8 1.2e-26 92.6 1.8 1.8 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 KZN93147.1 - 2.7e-16 59.2 0.7 4.9e-16 58.3 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KZN93147.1 - 2.7e-05 24.5 0.4 0.00013 22.4 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KZN93147.1 - 0.0013 18.8 0.6 0.0029 17.7 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KZN93147.1 - 0.0042 17.4 0.9 0.0079 16.5 0.0 1.8 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KZN93147.1 - 0.0054 16.6 0.0 0.0082 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 KZN93147.1 - 0.013 16.0 0.7 0.019 15.5 0.7 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KZN93147.1 - 0.021 14.9 1.0 5.9 7.0 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain IBR PF01485.21 KZN93147.1 - 0.028 14.6 0.2 0.048 13.9 0.2 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Glyco_hydro_18 PF00704.28 KZN93148.1 - 3.8e-87 292.9 0.1 4.4e-87 292.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PEP-utilizers PF00391.23 KZN93149.1 - 0.023 14.4 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain Proteasome PF00227.26 KZN93150.1 - 5.3e-51 172.8 0.1 7.3e-51 172.4 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KZN93150.1 - 5.2e-13 48.4 0.3 8.3e-13 47.8 0.3 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF2373 PF10180.9 KZN93151.1 - 2.7e-20 72.0 0.2 5.3e-20 71.0 0.2 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) GCP_C_terminal PF04130.13 KZN93152.1 - 2e-103 346.1 0.3 3.1e-103 345.5 0.3 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KZN93152.1 - 2.3e-83 280.4 0.0 7.2e-83 278.7 0.0 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal Fringe PF02434.16 KZN93153.1 - 5.2e-08 32.6 0.0 1.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Fringe-like PAN_4 PF14295.6 KZN93153.1 - 0.00013 21.8 0.4 0.00039 20.3 0.4 1.8 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 KZN93153.1 - 0.0012 18.7 0.1 0.003 17.5 0.1 1.6 1 0 0 1 1 1 1 PAN domain Galactosyl_T PF01762.21 KZN93153.1 - 0.017 15.0 0.0 0.58 9.9 0.0 2.3 1 1 0 2 2 2 0 Galactosyltransferase Aft1_HRA PF11786.8 KZN93154.1 - 3.6e-25 88.1 14.1 1.7e-24 85.9 9.5 3.0 2 0 0 2 2 2 1 Aft1 HRA domain Aft1_HRR PF11787.8 KZN93154.1 - 1.6e-21 77.2 6.4 1.6e-21 77.2 6.4 4.0 3 1 0 3 3 3 1 Aft1 HRR domain Aft1_OSA PF11785.8 KZN93154.1 - 4.4e-20 71.9 12.7 4.4e-20 71.9 12.7 3.8 4 0 0 4 4 4 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.21 KZN93154.1 - 5.5e-13 48.8 5.3 1.1e-12 47.8 5.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KZN93154.1 - 1.5e-05 25.0 6.7 3.6e-05 23.8 6.7 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KZN93154.1 - 0.0099 16.4 4.4 0.0099 16.4 4.4 2.5 1 1 1 2 2 2 1 bZIP Maf transcription factor Macoilin PF09726.9 KZN93154.1 - 4.5 5.7 16.0 6.2 5.2 16.0 1.1 1 0 0 1 1 1 0 Macoilin family Transthyretin PF00576.21 KZN93155.1 - 1.2e-32 112.9 0.0 1.4e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family ArsA_ATPase PF02374.15 KZN93156.1 - 1.7e-114 382.1 0.1 2e-114 381.9 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KZN93156.1 - 1e-13 51.6 0.3 9.3e-13 48.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 KZN93156.1 - 3e-13 49.9 0.0 6.9e-13 48.8 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 KZN93156.1 - 2.2e-06 27.3 0.1 5.2e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 KZN93156.1 - 1.7e-05 24.5 0.3 0.00083 19.0 0.1 2.7 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain ParA PF10609.9 KZN93156.1 - 1.8e-05 24.3 2.8 0.00013 21.5 0.1 2.5 3 0 0 3 3 3 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 KZN93156.1 - 8.3e-05 22.2 0.1 0.00029 20.4 0.0 1.8 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ PhoH PF02562.16 KZN93156.1 - 0.014 14.8 0.1 0.044 13.2 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.6 KZN93156.1 - 0.041 13.5 0.0 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain A1_Propeptide PF07966.12 KZN93156.1 - 0.1 12.5 2.1 0.13 12.2 0.1 2.3 2 0 0 2 2 2 0 A1 Propeptide eIF3_N PF09440.10 KZN93158.1 - 4.7e-51 172.7 2.2 1.2e-50 171.4 2.2 1.7 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KZN93158.1 - 4.2e-14 52.9 0.0 1.3e-13 51.4 0.0 1.9 1 0 0 1 1 1 1 PCI domain EF_assoc_1 PF08355.12 KZN93158.1 - 0.02 14.5 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 EF hand associated Img2 PF05046.14 KZN93159.1 - 2.5e-25 88.6 0.0 3.6e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) DUF4554 PF15091.6 KZN93159.1 - 0.075 11.9 0.3 0.098 11.5 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) ARID PF01388.21 KZN93160.1 - 6.5e-19 68.4 0.0 1.8e-18 67.0 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain AAA PF00004.29 KZN93161.1 - 2.1e-46 157.6 0.1 7.2e-46 155.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KZN93161.1 - 1.2e-10 41.2 0.1 7.6e-10 38.6 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 KZN93161.1 - 5e-09 36.5 0.0 1e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KZN93161.1 - 6.8e-09 35.9 0.6 2.2e-08 34.2 0.1 2.1 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KZN93161.1 - 1.9e-07 31.6 0.6 3.5e-05 24.2 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KZN93161.1 - 2.3e-05 24.7 1.1 0.0055 17.0 0.1 2.7 1 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 KZN93161.1 - 6.1e-05 22.3 0.0 0.00011 21.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 KZN93161.1 - 0.00021 21.3 0.0 0.00074 19.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 KZN93161.1 - 0.00023 20.9 0.1 0.00055 19.7 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KZN93161.1 - 0.00031 20.5 0.0 0.001 18.9 0.0 1.9 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KZN93161.1 - 0.00059 19.4 0.0 0.0061 16.1 0.1 2.4 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 KZN93161.1 - 0.0011 19.5 0.0 0.0034 17.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.15 KZN93161.1 - 0.0013 18.7 0.0 0.0048 16.8 0.0 1.9 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.22 KZN93161.1 - 0.0015 18.9 0.0 0.0031 17.9 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 KZN93161.1 - 0.0018 18.5 0.0 0.0043 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KZN93161.1 - 0.0019 17.5 0.0 0.0038 16.5 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 KZN93161.1 - 0.0037 17.3 0.0 0.0076 16.2 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 KZN93161.1 - 0.0047 16.8 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KZN93161.1 - 0.0052 16.7 0.3 0.11 12.4 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_28 PF13521.6 KZN93161.1 - 0.0075 16.5 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KZN93161.1 - 0.0078 15.6 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KZN93161.1 - 0.0085 15.8 0.2 0.2 11.3 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 KZN93161.1 - 0.0089 15.5 0.0 0.45 9.9 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein IstB_IS21 PF01695.17 KZN93161.1 - 0.012 15.4 0.1 0.045 13.5 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 KZN93161.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KZN93161.1 - 0.013 15.3 0.1 0.033 13.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KZN93161.1 - 0.044 13.7 1.2 0.41 10.5 0.0 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 KZN93161.1 - 0.045 13.5 0.1 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.16 KZN93161.1 - 0.064 12.1 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase Bac_DnaA PF00308.18 KZN93161.1 - 0.066 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_25 PF13481.6 KZN93161.1 - 0.067 12.8 1.1 0.22 11.1 0.4 2.2 2 1 1 3 3 3 0 AAA domain ATPase PF06745.13 KZN93161.1 - 0.077 12.3 0.9 0.91 8.8 0.0 2.4 3 0 0 3 3 2 0 KaiC Zeta_toxin PF06414.12 KZN93161.1 - 0.083 12.2 0.0 0.22 10.8 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 KZN93161.1 - 0.086 13.3 0.2 2.3 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KZN93161.1 - 0.13 12.6 0.1 0.4 11.0 0.1 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KZN93161.1 - 0.15 12.6 0.1 0.57 10.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 KZN93161.1 - 0.17 11.7 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_Hsp90 PF03225.14 KZN93161.1 - 0.17 10.3 0.0 0.27 9.7 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Parvo_NS1 PF01057.17 KZN93161.1 - 0.2 10.7 0.0 0.36 9.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Asp PF00026.23 KZN93162.1 - 6.3e-109 364.2 0.0 7.4e-109 364.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KZN93162.1 - 8.6e-17 61.9 1.2 1.2e-14 54.9 0.9 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KZN93162.1 - 3.4e-05 24.4 0.2 0.26 11.9 0.0 3.5 2 2 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KZN93162.1 - 0.00023 21.7 0.0 1.1 9.9 0.0 3.5 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KZN93162.1 - 0.011 15.5 0.0 0.16 11.7 0.0 2.4 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal NIF PF03031.18 KZN93163.1 - 4.3e-29 101.3 0.2 1.3e-28 99.7 0.0 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.26 KZN93163.1 - 4.1e-07 30.3 0.0 9.4e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KZN93163.1 - 0.00077 19.4 0.1 0.0017 18.3 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 KZN93163.1 - 0.0043 17.4 0.1 0.15 12.5 0.0 2.5 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KZN93163.1 - 0.018 14.9 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 KZN93163.1 - 0.047 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain MARVEL PF01284.23 KZN93164.1 - 0.0052 16.8 15.6 0.0079 16.2 15.6 1.3 1 0 0 1 1 1 1 Membrane-associating domain Papilloma_E5A PF05776.12 KZN93164.1 - 3.6 8.0 14.9 0.25 11.7 9.0 2.1 2 1 0 2 2 2 0 Papillomavirus E5A protein Arginase PF00491.21 KZN93165.1 - 1.3e-78 264.4 0.6 1.5e-78 264.2 0.6 1.0 1 0 0 1 1 1 1 Arginase family GatB_N PF02934.15 KZN93166.1 - 4.3e-97 324.8 0.0 5.8e-97 324.4 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KZN93166.1 - 4.7e-26 91.5 0.0 9.5e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 GatB domain DUF885 PF05960.11 KZN93166.1 - 0.053 13.2 0.5 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) UNC-93 PF05978.16 KZN93167.1 - 9.8e-11 41.6 4.1 3.9e-10 39.7 3.0 2.5 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KZN93167.1 - 4.7e-08 32.3 31.0 4.7e-08 32.3 31.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN93167.1 - 0.32 9.8 22.8 0.18 10.6 18.4 2.7 2 1 0 2 2 2 0 Sugar (and other) transporter DAO PF01266.24 KZN93168.1 - 6.2e-39 134.6 0.0 7.1e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KZN93168.1 - 0.0022 17.3 0.0 0.95 8.6 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KZN93168.1 - 0.023 13.8 0.0 0.69 8.9 0.0 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KZN93168.1 - 0.034 14.1 0.2 3.4 7.6 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Ldh_1_N PF00056.23 KZN93168.1 - 0.071 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 KZN93168.1 - 0.081 13.2 0.0 0.28 11.4 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain F420_oxidored PF03807.17 KZN93168.1 - 0.095 13.3 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Trp_halogenase PF04820.14 KZN93168.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase SH3_19 PF18597.1 KZN93168.1 - 0.18 11.7 0.0 0.43 10.4 0.0 1.6 1 0 0 1 1 1 0 Myosin X N-terminal SH3 domain Dioxygenase_C PF00775.21 KZN93170.1 - 6.5e-06 25.7 0.1 9.1e-06 25.2 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase DUF2808 PF10989.8 KZN93171.1 - 0.072 13.1 0.2 0.11 12.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) IMUP PF15761.5 KZN93172.1 - 0.016 15.9 3.3 0.051 14.3 3.3 1.9 1 0 0 1 1 1 0 Immortalisation up-regulated protein Osw5 PF17062.5 KZN93172.1 - 0.43 10.7 2.6 0.97 9.6 2.6 1.5 1 0 0 1 1 1 0 Outer spore wall 5 ECH_1 PF00378.20 KZN93175.1 - 8.7e-44 149.7 0.0 2.3e-43 148.3 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KZN93175.1 - 5.7e-27 95.1 0.0 9.8e-27 94.3 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase RelE PF06296.12 KZN93175.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 RelE toxin of RelE / RelB toxin-antitoxin system LmjF365940-deam PF14421.6 KZN93175.1 - 0.11 12.1 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases NB-ARC PF00931.22 KZN93176.1 - 5.2e-12 45.5 0.0 8.4e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KZN93176.1 - 1.8e-06 28.4 0.0 4.2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF676 PF05057.14 KZN93176.1 - 0.00071 19.1 0.4 0.003 17.1 0.4 1.9 1 1 0 1 1 1 1 Putative serine esterase (DUF676) NACHT PF05729.12 KZN93176.1 - 0.00094 19.1 0.1 0.0063 16.4 0.0 2.1 2 0 0 2 2 2 1 NACHT domain ATPase PF06745.13 KZN93176.1 - 0.0032 16.9 0.0 0.0065 15.8 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.6 KZN93176.1 - 0.0043 17.3 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KZN93176.1 - 0.007 15.7 0.4 0.03 13.6 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin PGAP1 PF07819.13 KZN93176.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein AAA_33 PF13671.6 KZN93176.1 - 0.083 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KZN93176.1 - 0.097 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 KZN93176.1 - 0.11 12.3 0.0 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ADH_zinc_N_2 PF13602.6 KZN93177.1 - 2.5e-22 80.3 0.0 4.1e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KZN93177.1 - 6.7e-19 68.2 0.0 1.2e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 KZN93177.1 - 0.004 16.9 0.8 0.0059 16.4 0.8 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Epimerase PF01370.21 KZN93177.1 - 0.072 12.5 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Transp_cyt_pur PF02133.15 KZN93179.1 - 9.2e-102 341.1 29.5 1.1e-101 340.8 29.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DIOX_N PF14226.6 KZN93180.1 - 6e-27 94.7 0.1 8.9e-27 94.2 0.1 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KZN93180.1 - 9.3e-20 71.0 0.1 2.8e-19 69.5 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 KZN93182.1 - 1.4e-42 145.9 60.1 2.1e-42 145.3 54.9 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KZN93182.1 - 1.1e-12 47.2 27.3 1.5e-12 46.8 27.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Apolipoprotein PF01442.18 KZN93183.1 - 0.015 15.2 1.0 0.02 14.8 1.0 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain ATP-synt_B PF00430.18 KZN93183.1 - 0.18 11.9 8.7 0.26 11.4 8.7 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF883 PF05957.13 KZN93183.1 - 0.19 12.3 5.6 1.2 9.8 2.0 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 KZN93183.1 - 2.9 8.5 16.7 1.9e+03 -0.5 16.7 2.4 1 1 0 1 1 1 0 YtxH-like protein FHA PF00498.26 KZN93184.1 - 8.9e-14 51.6 0.0 2.3e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KZN93184.1 - 0.043 14.1 0.0 1 9.7 0.0 2.2 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain DnaJ PF00226.31 KZN93185.1 - 1.7e-10 40.8 1.4 3.8e-10 39.7 1.4 1.6 1 0 0 1 1 1 1 DnaJ domain DUF1459 PF07312.11 KZN93185.1 - 0.013 15.7 0.2 0.026 14.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1459) HATPase_c PF02518.26 KZN93186.1 - 3.4e-22 79.1 0.3 1.5e-21 77.0 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KZN93186.1 - 2.5e-20 72.7 0.4 8.1e-20 71.1 0.1 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KZN93186.1 - 4e-16 58.8 0.1 4e-16 58.8 0.1 2.8 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 KZN93186.1 - 3.5e-10 40.0 5.1 0.0023 18.2 0.2 4.4 3 2 1 4 4 4 3 PAS fold PAS_4 PF08448.10 KZN93186.1 - 3.3e-06 27.3 0.1 6.4e-05 23.2 0.0 2.9 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 KZN93186.1 - 0.00022 21.4 0.1 0.2 11.9 0.0 3.7 3 1 0 3 3 3 1 PAS domain PAS PF00989.25 KZN93186.1 - 0.0031 17.5 0.0 4.3 7.4 0.0 3.0 2 0 0 2 2 2 2 PAS fold MotA_ExbB PF01618.16 KZN93186.1 - 0.047 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family HSBP1 PF06825.12 KZN93186.1 - 0.33 10.9 4.1 7.7 6.5 0.2 3.3 3 0 0 3 3 3 0 Heat shock factor binding protein 1 CagA PF03507.13 KZN93186.1 - 1.3 8.9 3.5 0.76 9.7 0.4 2.2 3 0 0 3 3 3 0 CagA exotoxin KxDL PF10241.9 KZN93187.1 - 7.7e-32 109.4 1.2 9.7e-32 109.1 1.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF4407 PF14362.6 KZN93187.1 - 0.027 13.8 1.9 0.032 13.6 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA PF00004.29 KZN93188.1 - 1.4e-53 180.8 0.0 2.9e-39 134.5 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.17 KZN93188.1 - 1.6e-11 43.8 0.2 3.5e-10 39.5 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_lid_3 PF17862.1 KZN93188.1 - 7.1e-11 41.7 0.1 1.6e-10 40.6 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KZN93188.1 - 1.1e-08 35.4 0.0 0.00011 22.5 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KZN93188.1 - 3.1e-08 34.2 0.2 0.0061 17.0 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain RuvB_N PF05496.12 KZN93188.1 - 1.6e-06 28.0 0.1 0.073 12.8 0.1 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain CDC48_N PF02359.18 KZN93188.1 - 1.8e-06 28.0 0.0 4.4e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 KZN93188.1 - 2e-06 28.0 0.0 0.00013 22.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 KZN93188.1 - 2e-06 27.3 0.1 0.0045 16.4 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KZN93188.1 - 2.9e-06 26.7 0.1 0.025 13.8 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_5 PF07728.14 KZN93188.1 - 4.5e-06 26.7 0.0 0.0012 18.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KZN93188.1 - 5e-06 26.7 0.0 0.07 13.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 KZN93188.1 - 5.6e-06 26.4 0.0 0.13 12.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KZN93188.1 - 4.1e-05 24.1 0.0 0.089 13.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 KZN93188.1 - 4.9e-05 23.1 0.0 0.019 14.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KZN93188.1 - 0.00012 22.0 0.9 24 4.8 0.0 4.2 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KZN93188.1 - 0.00039 20.8 0.0 0.065 13.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.6 KZN93188.1 - 0.0004 20.7 0.0 1.3 9.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KZN93188.1 - 0.0011 18.5 0.1 0.043 13.3 0.0 2.8 4 0 0 4 4 2 1 P-loop containing dynein motor region TsaE PF02367.17 KZN93188.1 - 0.0015 18.5 0.0 0.42 10.6 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KZN93188.1 - 0.0037 17.0 0.0 0.19 11.4 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 KZN93188.1 - 0.0055 16.1 0.1 0.076 12.3 0.1 2.3 2 0 0 2 2 2 1 KaiC Parvo_NS1 PF01057.17 KZN93188.1 - 0.0058 15.8 0.0 0.93 8.5 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 NACHT PF05729.12 KZN93188.1 - 0.0089 16.0 0.2 6.2 6.7 0.0 2.8 3 0 0 3 3 2 0 NACHT domain ABC_tran PF00005.27 KZN93188.1 - 0.0091 16.5 0.2 0.057 13.9 0.1 2.3 2 0 0 2 2 2 1 ABC transporter AAA_25 PF13481.6 KZN93188.1 - 0.0094 15.5 0.4 3.1 7.3 0.0 3.0 2 2 1 3 3 3 1 AAA domain NB-ARC PF00931.22 KZN93188.1 - 0.0095 15.1 0.1 1.9 7.6 0.1 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_11 PF13086.6 KZN93188.1 - 0.017 15.0 0.0 0.67 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KZN93188.1 - 0.028 14.1 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_17 PF13207.6 KZN93188.1 - 0.029 14.8 0.1 15 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 KZN93188.1 - 0.034 13.6 0.0 6.1 6.2 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_3 PF07726.11 KZN93188.1 - 0.04 13.8 0.0 0.51 10.2 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KZN93188.1 - 0.051 13.9 0.0 0.74 10.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain TniB PF05621.11 KZN93188.1 - 0.052 13.0 0.0 4 6.8 0.0 2.9 2 1 1 3 3 3 0 Bacterial TniB protein PhoH PF02562.16 KZN93188.1 - 0.072 12.5 0.1 2.7 7.4 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.6 KZN93188.1 - 0.093 12.4 0.0 0.7 9.6 0.0 2.4 3 0 0 3 3 3 0 AAA domain Cir_N PF10197.9 KZN93189.1 - 5.6e-06 26.4 3.4 5.6e-06 26.4 3.4 2.8 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR Methyltransf_25 PF13649.6 KZN93190.1 - 3e-11 43.9 0.0 8e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN93190.1 - 3e-09 37.4 0.0 7.1e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KZN93190.1 - 3.4e-09 36.5 0.3 6.8e-09 35.5 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KZN93190.1 - 1.8e-08 34.4 0.0 3.9e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KZN93190.1 - 2.4e-06 27.6 0.2 5e-06 26.5 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KZN93190.1 - 1.6e-05 24.5 0.2 3.6e-05 23.4 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KZN93190.1 - 3.4e-05 23.7 0.0 7e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KZN93190.1 - 0.00076 18.9 0.1 0.0014 18.1 0.1 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.11 KZN93190.1 - 0.0011 18.0 0.0 0.0021 17.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 KZN93190.1 - 0.0041 17.8 0.0 0.01 16.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KZN93190.1 - 0.016 15.0 0.1 0.027 14.2 0.1 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Ubie_methyltran PF01209.18 KZN93190.1 - 0.016 14.5 0.0 0.032 13.6 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PRMT5 PF05185.16 KZN93190.1 - 0.028 14.3 1.2 0.55 10.1 1.2 2.2 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_24 PF13578.6 KZN93190.1 - 0.032 15.2 0.0 0.1 13.6 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain DHR10 PF18595.1 KZN93190.1 - 0.039 14.0 0.6 0.075 13.1 0.6 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain PCMT PF01135.19 KZN93190.1 - 0.049 13.4 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 KZN93190.1 - 0.051 12.9 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 KZN93190.1 - 0.066 12.9 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 KZN93190.1 - 0.12 11.7 0.1 0.21 10.8 0.1 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Surfac_D-trimer PF09006.11 KZN93190.1 - 0.15 12.0 0.4 1.4 8.9 0.3 2.6 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation Methyltransf_32 PF13679.6 KZN93190.1 - 0.21 11.6 0.5 0.92 9.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Mo25 PF08569.11 KZN93191.1 - 3.4e-130 434.2 0.3 3.9e-130 434.0 0.3 1.0 1 0 0 1 1 1 1 Mo25-like RabGAP-TBC PF00566.18 KZN93192.1 - 4.6e-33 114.7 0.0 6.9e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain 3HCDH_N PF02737.18 KZN93193.1 - 9.5e-32 110.3 0.0 1.8e-31 109.4 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KZN93193.1 - 2.8e-15 56.7 0.1 6.2e-15 55.6 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.23 KZN93193.1 - 2.5e-06 27.6 0.0 3.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 KZN93193.1 - 3.1e-05 24.2 0.3 9.1e-05 22.7 0.3 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KZN93193.1 - 0.012 16.2 1.4 0.067 13.8 1.3 2.2 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.24 KZN93193.1 - 0.014 15.0 0.1 0.016 14.8 0.1 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase SWIRM-assoc_1 PF16495.5 KZN93193.1 - 0.15 12.1 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 SWIRM-associated region 1 MFS_1 PF07690.16 KZN93194.1 - 4e-41 141.1 29.5 5.9e-41 140.6 29.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_5_1 PF06946.11 KZN93194.1 - 0.12 12.8 0.1 0.12 12.8 0.1 2.6 3 0 0 3 3 3 0 Bacteriophage A118-like holin, Hol118 FeoB_C PF07664.12 KZN93194.1 - 0.69 9.6 0.0 0.69 9.6 0.0 4.1 5 1 1 6 6 6 0 Ferrous iron transport protein B C terminus Cg6151-P PF10233.9 KZN93195.1 - 9.6e-41 138.6 12.9 1.1e-40 138.4 12.9 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P PEMT PF04191.13 KZN93195.1 - 0.012 15.9 8.7 0.48 10.8 0.5 2.3 1 1 1 2 2 2 0 Phospholipid methyltransferase CbiQ PF02361.16 KZN93195.1 - 0.14 11.7 10.0 0.19 11.3 10.0 1.1 1 0 0 1 1 1 0 Cobalt transport protein COPI_assoc PF08507.10 KZN93195.1 - 0.32 11.0 12.3 0.46 10.5 12.3 1.3 1 0 0 1 1 1 0 COPI associated protein DUF4149 PF13664.6 KZN93195.1 - 0.33 11.3 6.6 0.33 11.3 2.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) DHHC PF01529.20 KZN93195.1 - 2.9 8.0 5.6 5.1 7.2 5.6 1.4 1 1 0 1 1 1 0 DHHC palmitoyltransferase Aim21 PF11489.8 KZN93196.1 - 1.3e-243 811.1 87.2 1.3e-243 811.1 87.2 2.6 2 1 0 2 2 2 1 Altered inheritance of mitochondria protein 21 FANCL_C PF11793.8 KZN93197.1 - 1.3e-06 28.5 2.8 2.4e-06 27.6 2.8 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.7 KZN93197.1 - 1.4e-05 25.2 6.3 2.5e-05 24.3 6.3 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KZN93197.1 - 0.058 13.7 5.3 0.11 12.8 5.3 1.5 1 0 0 1 1 1 0 Ring finger domain MRP-L28 PF09812.9 KZN93198.1 - 3.4e-08 33.8 0.0 4.9e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 NST1 PF13945.6 KZN93199.1 - 8.7e-67 225.0 0.0 8.7e-67 225.0 0.0 4.3 3 1 1 4 4 4 1 Salt tolerance down-regulator Red1 PF07964.11 KZN93199.1 - 10 4.2 36.7 22 3.1 36.7 1.6 1 0 0 1 1 1 0 Rec10 / Red1 Vps35 PF03635.17 KZN93200.1 - 0 1021.4 0.2 0 1021.3 0.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF4746 PF15928.5 KZN93200.1 - 0.61 9.5 6.3 1 8.7 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Zn-ribbon_8 PF09723.10 KZN93201.1 - 1.5 9.0 5.5 1.7 8.8 0.6 3.0 3 0 0 3 3 3 0 Zinc ribbon domain AAA_12 PF13087.6 KZN93202.1 - 1.2e-38 132.8 0.0 2.2e-38 131.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KZN93202.1 - 7.8e-27 94.7 0.1 1.5e-26 93.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KZN93202.1 - 9.6e-10 39.0 0.2 3.6e-08 33.8 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KZN93202.1 - 4.2e-05 23.3 1.0 0.0045 16.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain UvrD-helicase PF00580.21 KZN93202.1 - 0.00012 21.7 0.0 0.0003 20.4 0.0 1.6 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 KZN93202.1 - 0.0051 16.1 0.1 0.053 12.8 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 KZN93202.1 - 0.0065 16.2 0.0 1.9 8.2 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KZN93202.1 - 0.0087 16.1 0.0 0.026 14.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-CCCH_4 PF18044.1 KZN93202.1 - 0.35 10.7 6.2 0.19 11.6 3.5 2.1 2 0 0 2 2 2 0 CCCH-type zinc finger zf-CCCH PF00642.24 KZN93202.1 - 0.55 10.2 6.8 0.39 10.7 2.3 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KZN93202.1 - 6 7.1 7.5 13 6.0 3.9 3.0 2 1 0 2 2 2 0 Zinc finger domain TPP_enzyme_N PF02776.18 KZN93203.1 - 1.8e-55 187.2 0.0 6.6e-55 185.4 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KZN93203.1 - 7.7e-48 162.1 0.0 1.2e-46 158.2 0.0 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KZN93203.1 - 7e-39 132.7 0.1 1.3e-38 131.9 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 KZN93203.1 - 0.065 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg GalKase_gal_bdg PF10509.9 KZN93204.1 - 5.2e-19 67.5 0.0 1.1e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 KZN93204.1 - 3e-15 56.2 1.4 7.5e-15 54.9 1.4 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KZN93204.1 - 1.4e-12 47.7 0.0 3.7e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal RNase_H2-Ydr279 PF09468.10 KZN93205.1 - 1.9e-39 135.4 0.5 4.1e-39 134.3 0.0 1.8 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KZN93205.1 - 6.9e-19 67.9 0.0 2.2e-18 66.2 0.0 2.0 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain Alpha_GJ PF03229.13 KZN93205.1 - 3 8.4 5.1 6.8 7.3 5.1 1.5 1 0 0 1 1 1 0 Alphavirus glycoprotein J zf-primase PF09329.11 KZN93206.1 - 3.1e-18 65.3 2.3 5.2e-18 64.6 2.3 1.4 1 0 0 1 1 1 1 Primase zinc finger PP2C PF00481.21 KZN93209.1 - 3.4e-42 144.9 0.0 5.7e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C FCH PF00611.23 KZN93210.1 - 4.2e-14 52.6 0.1 1.3e-13 51.0 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KZN93210.1 - 6e-13 48.2 0.0 1.1e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KZN93210.1 - 1.8e-11 43.6 0.0 5.4e-11 42.0 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KZN93210.1 - 2.7e-11 43.1 0.0 5.4e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PCSK9_C1 PF18459.1 KZN93211.1 - 0.18 12.0 1.8 21 5.4 0.3 3.1 2 0 0 2 2 2 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain Trypan_PARP PF05887.11 KZN93212.1 - 5.4 7.0 8.0 14 5.6 8.0 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Abhydrolase_1 PF00561.20 KZN93213.1 - 3.7e-09 36.6 0.4 1e-08 35.2 0.4 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KZN93213.1 - 2e-06 28.6 2.4 2.5e-06 28.3 2.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KZN93213.1 - 0.00055 19.3 0.1 0.00092 18.5 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 KZN93213.1 - 0.034 13.2 0.0 0.054 12.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Peptidase_S9 PF00326.21 KZN93213.1 - 0.076 12.5 0.3 0.21 11.0 0.1 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF1749 PF08538.10 KZN93214.1 - 5.5e-104 347.4 0.0 6.3e-104 347.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 KZN93214.1 - 0.00015 22.4 0.0 0.00019 22.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3349 PF11829.8 KZN93214.1 - 0.14 13.0 0.1 0.37 11.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) PGAP1 PF07819.13 KZN93214.1 - 0.19 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Glycos_transf_2 PF00535.26 KZN93215.1 - 1.6e-36 125.6 0.0 2e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KZN93215.1 - 1e-12 48.4 0.0 1.4e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KZN93215.1 - 5.7e-06 26.0 0.0 8.4e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KZN93215.1 - 0.00083 18.9 0.0 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 KZN93215.1 - 0.12 12.9 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 KZN93215.1 - 0.19 11.6 2.2 0.39 10.6 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family group 2 TPR_19 PF14559.6 KZN93216.1 - 8.9e-07 29.3 0.2 0.07 13.6 0.0 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KZN93216.1 - 9.1e-05 23.0 0.2 0.016 15.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KZN93216.1 - 0.0072 17.1 2.8 40 5.4 0.1 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KZN93216.1 - 0.011 15.8 0.2 9.7 6.6 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KZN93216.1 - 0.021 15.1 0.3 0.86 9.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KZN93216.1 - 0.039 13.6 0.4 1.4 8.5 0.0 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_4 PF07721.14 KZN93216.1 - 0.046 14.3 6.6 10 7.1 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KZN93216.1 - 0.17 12.4 0.6 5.3 7.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat SAC3_GANP PF03399.16 KZN93217.1 - 0.00029 20.3 0.0 0.00042 19.8 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KZN93217.1 - 0.00051 20.0 0.1 0.00094 19.2 0.1 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family HlyIII PF03006.20 KZN93218.1 - 3.4e-63 213.3 9.8 4.1e-63 213.1 9.8 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF998 PF06197.13 KZN93218.1 - 1.7 8.2 17.3 0.21 11.2 10.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF998) Zn_clus PF00172.18 KZN93219.1 - 9.9e-08 32.0 8.0 9.9e-08 32.0 8.0 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 KZN93220.1 - 1.4e-48 165.5 5.8 3.6e-39 134.7 6.1 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN93220.1 - 3e-44 150.8 5.5 3.7e-44 150.5 5.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN93220.1 - 6.3e-16 58.8 1.1 8.3e-16 58.4 1.1 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KZN93220.1 - 0.00073 19.5 1.1 0.0012 18.8 1.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KZN93220.1 - 0.0088 15.2 0.1 0.013 14.7 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein AdoHcyase_NAD PF00670.21 KZN93220.1 - 0.018 15.1 0.5 0.03 14.4 0.5 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KZN93220.1 - 0.066 12.6 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KZN93220.1 - 0.093 12.8 0.2 0.19 11.8 0.2 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pkinase PF00069.25 KZN93221.1 - 6.2e-54 183.1 0.0 8.1e-54 182.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN93221.1 - 6.5e-34 117.4 0.0 7.9e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KZN93221.1 - 7.9e-06 25.4 0.0 0.0007 19.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KZN93221.1 - 8.7e-05 22.6 0.0 0.0016 18.4 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KZN93221.1 - 0.02 13.8 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KZN93221.1 - 0.046 13.1 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KZN93221.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 KZN93221.1 - 0.13 11.9 0.0 1.5 8.4 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 UL11 PF11094.8 KZN93221.1 - 0.14 12.0 1.1 0.22 11.4 0.1 1.9 2 0 0 2 2 2 0 Membrane-associated tegument protein Pkinase PF00069.25 KZN93222.1 - 1.2e-49 169.1 0.0 1.6e-49 168.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN93222.1 - 4.2e-22 78.7 0.0 9.7e-22 77.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KZN93222.1 - 0.087 11.8 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TMA7 PF09072.10 KZN93223.1 - 1.9e-22 79.8 23.3 2.2e-22 79.7 23.3 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 DHR10 PF18595.1 KZN93224.1 - 0.051 13.6 2.6 0.086 12.9 2.6 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Cyt-b5 PF00173.28 KZN93225.1 - 1.6e-14 53.8 0.0 2.3e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FixQ PF05545.11 KZN93225.1 - 0.033 14.2 0.4 0.064 13.2 0.4 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Ish1 PF10281.9 KZN93226.1 - 4.8e-86 282.7 20.1 3.5e-13 49.6 0.0 7.4 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein SAP PF02037.27 KZN93226.1 - 1.1e-10 40.9 0.0 1.6 8.6 0.0 6.3 6 1 0 6 6 6 4 SAP domain HeH PF12949.7 KZN93226.1 - 7.4e-10 38.4 0.5 0.18 11.6 0.2 5.2 6 0 0 6 6 6 2 HeH/LEM domain ANAPC2 PF08672.11 KZN93226.1 - 2.8e-05 24.6 0.4 32 5.1 0.0 5.7 6 0 0 6 6 6 0 Anaphase promoting complex (APC) subunit 2 Slx4 PF09494.10 KZN93226.1 - 0.00028 20.8 0.6 21 5.1 0.0 5.3 6 0 0 6 6 6 0 Slx4 endonuclease Thymopoietin PF08198.11 KZN93226.1 - 0.0033 17.0 0.0 0.23 11.1 0.0 3.5 4 0 0 4 4 4 1 Thymopoietin protein LEM PF03020.15 KZN93226.1 - 0.0042 16.6 0.0 22 4.7 0.0 4.5 5 0 0 5 5 5 0 LEM domain CPSase_sm_chain PF00988.22 KZN93226.1 - 0.011 15.5 0.1 5.4 6.9 0.0 4.4 5 1 1 6 6 6 0 Carbamoyl-phosphate synthase small chain, CPSase domain DUF4224 PF13986.6 KZN93226.1 - 0.014 15.3 0.0 15 5.5 0.0 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4224) SLATT_4 PF18186.1 KZN93226.1 - 0.14 11.8 2.4 0.35 10.5 2.4 1.8 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 Caudo_TAP PF02413.17 KZN93226.1 - 0.23 11.6 6.1 0.8 9.9 0.9 2.9 1 1 1 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK Phasin PF05597.11 KZN93226.1 - 1.1 9.3 9.0 1.7 8.7 0.3 4.2 5 0 0 5 5 5 0 Poly(hydroxyalcanoate) granule associated protein (phasin) SAM_2 PF07647.17 KZN93226.1 - 2.1 8.5 9.3 42 4.4 0.2 4.9 6 0 0 6 6 5 0 SAM domain (Sterile alpha motif) APH PF01636.23 KZN93227.1 - 1.4e-13 51.3 0.0 3.1e-13 50.2 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KZN93227.1 - 0.036 12.9 0.0 0.28 10.0 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) DUF481 PF04338.12 KZN93227.1 - 0.22 11.5 0.0 12 5.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF481 PQ-loop PF04193.14 KZN93228.1 - 2e-20 72.3 22.4 5.5e-12 45.3 2.7 3.5 3 1 1 4 4 4 2 PQ loop repeat NTF2 PF02136.20 KZN93229.1 - 3e-34 118.2 0.2 3.3e-34 118.0 0.2 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Surp PF01805.20 KZN93230.1 - 7.2e-12 45.1 0.0 1.7e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Surp module DUF3169 PF11368.8 KZN93231.1 - 0.022 14.3 0.3 0.035 13.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Not1 PF04054.15 KZN93232.1 - 2.9e-139 464.1 0.2 5.1e-139 463.3 0.2 1.4 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KZN93232.1 - 2.6e-95 318.1 0.2 6.7e-95 316.7 0.2 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 KZN93232.1 - 7.7e-52 175.1 1.6 1.7e-51 174.0 1.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 KZN93232.1 - 1.1e-40 138.8 0.0 3.1e-40 137.4 0.0 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 KZN93232.1 - 7.1e-29 100.8 0.7 4.1e-28 98.4 0.0 2.6 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Zemlya PF17646.1 KZN93232.1 - 0.11 12.8 0.1 0.35 11.3 0.1 1.9 1 0 0 1 1 1 0 Closterovirus 1a polyprotein central region Seipin PF06775.14 KZN93233.1 - 2.4e-62 210.6 0.0 3.1e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) TTL PF03133.15 KZN93234.1 - 5.2e-56 189.9 0.0 7.7e-56 189.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 KZN93234.1 - 3e-08 33.7 0.0 4.6e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 KZN93234.1 - 2.7e-05 23.6 0.0 0.00024 20.5 0.0 2.0 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KZN93234.1 - 0.013 14.8 0.0 0.093 12.0 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 KZN93234.1 - 0.097 12.2 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus PrpF PF04303.13 KZN93235.1 - 3.1e-106 355.5 0.2 3.5e-106 355.3 0.2 1.0 1 0 0 1 1 1 1 PrpF protein Pex14_N PF04695.13 KZN93237.1 - 5.8e-45 153.8 0.7 5.8e-45 153.8 0.7 3.3 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Baculo_PEP_C PF04513.12 KZN93237.1 - 0.0063 16.6 1.6 0.053 13.6 1.8 2.2 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.8 KZN93237.1 - 0.013 13.1 4.2 0.017 12.7 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Golgin_A5 PF09787.9 KZN93237.1 - 0.022 14.2 0.7 0.034 13.6 0.7 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF1043 PF06295.12 KZN93237.1 - 0.084 12.9 0.2 0.18 11.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) LMBR1 PF04791.16 KZN93237.1 - 0.27 10.1 0.0 0.36 9.7 0.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF812 PF05667.11 KZN93237.1 - 0.33 9.8 3.0 0.71 8.7 3.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) ERM PF00769.19 KZN93237.1 - 0.61 9.9 8.2 0.28 11.0 4.5 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF1664 PF07889.12 KZN93237.1 - 3.2 7.8 4.9 0.7 9.9 0.8 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Ndc80_HEC PF03801.13 KZN93238.1 - 8.6e-60 200.8 0.0 1.9e-59 199.6 0.0 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family CENP-F_leu_zip PF10473.9 KZN93238.1 - 0.0011 19.0 9.8 0.0011 19.0 9.8 4.2 2 2 2 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 KZN93238.1 - 0.0077 15.8 21.5 0.0077 15.8 21.5 2.7 2 1 0 2 2 2 1 Intermediate filament protein DUF16 PF01519.16 KZN93238.1 - 0.017 15.6 6.4 0.017 15.6 6.4 3.7 2 2 2 4 4 4 0 Protein of unknown function DUF16 Strep_SA_rep PF06696.11 KZN93238.1 - 0.43 10.6 2.1 43 4.3 0.0 3.6 3 0 0 3 3 3 0 Streptococcal surface antigen repeat Prominin PF05478.11 KZN93238.1 - 2 6.3 21.0 0.11 10.4 6.8 2.1 2 0 0 2 2 2 0 Prominin Jnk-SapK_ap_N PF09744.9 KZN93238.1 - 3.8 7.7 46.3 1.6 8.9 7.8 3.5 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Exonuc_VII_L PF02601.15 KZN93238.1 - 4.7 6.7 24.1 0.78 9.2 6.6 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit TPR_MLP1_2 PF07926.12 KZN93238.1 - 8.1 6.5 43.7 0.92 9.6 12.4 4.3 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KZN93238.1 - 9.2 5.0 44.3 1 8.2 14.2 3.2 2 2 1 3 3 3 0 Spc7 kinetochore protein RVT_3 PF13456.6 KZN93239.1 - 0.0039 17.0 0.4 0.049 13.4 0.4 2.0 1 1 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.24 KZN93239.1 - 0.0087 16.2 0.1 0.012 15.8 0.1 1.2 1 0 0 1 1 1 1 RNase H PT PF04886.12 KZN93240.1 - 0.011 15.2 53.2 0.11 12.1 11.1 4.2 3 2 1 4 4 4 0 PT repeat Fungal_trans PF04082.18 KZN93242.1 - 4.8e-19 68.4 0.0 7.5e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN93242.1 - 6.7e-08 32.5 10.5 1.3e-07 31.6 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PIF PF05092.12 KZN93242.1 - 0.31 9.7 1.1 0.47 9.1 1.1 1.1 1 0 0 1 1 1 0 Per os infectivity GST_N PF02798.20 KZN93244.1 - 2.1e-15 56.8 0.0 5.9e-14 52.2 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KZN93244.1 - 1.1e-14 54.4 0.0 1.3e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KZN93244.1 - 2.6e-13 50.2 0.0 4.5e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KZN93244.1 - 1.6e-12 47.5 0.0 2.5e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KZN93244.1 - 1.7e-10 41.0 0.0 3.4e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KZN93244.1 - 5e-06 26.4 0.0 9.4e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KZN93244.1 - 0.087 13.1 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein A_deaminase PF00962.22 KZN93245.1 - 3.5e-17 62.7 0.0 4.5e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase MFS_1 PF07690.16 KZN93246.1 - 1.1e-28 100.2 32.4 1.1e-28 100.2 32.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KZN93246.1 - 1.3e-06 28.0 5.3 1.3e-06 28.0 5.3 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Methyltransf_23 PF13489.6 KZN93247.1 - 4.5e-34 117.7 0.0 6.6e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN93247.1 - 2.2e-06 28.3 0.1 1.6e-05 25.5 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN93247.1 - 6.1e-06 26.9 0.0 1.3e-05 25.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN93247.1 - 0.0013 19.3 0.0 0.0055 17.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN93247.1 - 0.0018 18.1 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Retinal PF15449.6 KZN93247.1 - 0.45 8.2 8.0 0.54 8.0 8.0 1.0 1 0 0 1 1 1 0 Retinal protein DAO PF01266.24 KZN93248.1 - 8.3e-47 160.5 0.5 9.5e-47 160.3 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KZN93248.1 - 8.9e-08 31.7 0.0 0.01 15.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KZN93248.1 - 6.4e-07 29.5 0.2 0.03 14.3 0.1 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KZN93248.1 - 5e-06 25.8 0.1 0.0031 16.6 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Trp_halogenase PF04820.14 KZN93248.1 - 2.4e-05 23.4 0.0 0.018 13.9 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase GIDA PF01134.22 KZN93248.1 - 0.00012 21.4 0.0 0.00087 18.5 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KZN93248.1 - 0.00024 21.3 0.0 0.00055 20.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KZN93248.1 - 0.0009 19.8 0.0 0.0022 18.5 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 KZN93248.1 - 0.0022 17.4 0.0 0.46 9.8 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.24 KZN93248.1 - 0.0028 16.8 0.1 0.41 9.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KZN93248.1 - 0.0065 15.7 0.0 0.016 14.5 0.0 1.5 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 KZN93248.1 - 0.0075 15.6 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KZN93248.1 - 0.038 14.2 0.0 0.078 13.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.19 KZN93248.1 - 0.097 11.9 0.0 0.91 8.7 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain TBP PF00352.21 KZN93249.1 - 1.4e-67 223.6 0.1 9.9e-33 112.0 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KZN93249.1 - 6.9e-05 22.9 0.0 0.24 11.6 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 KZN93249.1 - 0.14 12.0 0.1 0.72 9.7 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) ETF_QO PF05187.13 KZN93250.1 - 1e-47 160.6 0.3 1.6e-47 159.9 0.3 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 KZN93250.1 - 2.2e-07 30.3 0.4 0.0016 17.6 0.7 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KZN93250.1 - 5.2e-07 29.6 0.4 0.00037 20.2 0.4 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KZN93250.1 - 1.8e-06 28.1 0.0 6e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KZN93250.1 - 2.3e-05 23.8 0.0 7.1e-05 22.2 0.0 1.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KZN93250.1 - 0.00015 21.3 0.0 0.00022 20.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KZN93250.1 - 0.00044 19.1 0.5 0.00069 18.4 0.5 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KZN93250.1 - 0.0006 20.3 0.4 0.72 10.4 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KZN93250.1 - 0.00099 18.4 0.3 0.002 17.5 0.3 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KZN93250.1 - 0.0012 18.8 0.1 0.0046 17.0 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KZN93250.1 - 0.0024 17.1 0.0 0.018 14.3 0.1 1.9 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.14 KZN93250.1 - 0.0028 16.6 0.1 0.18 10.6 0.2 2.2 1 1 1 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 KZN93250.1 - 0.008 15.5 0.7 0.012 14.8 0.7 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.7 KZN93250.1 - 0.016 15.8 0.9 0.043 14.4 0.9 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Lycopene_cycl PF05834.12 KZN93250.1 - 0.078 12.0 0.3 0.12 11.4 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 KZN93250.1 - 0.12 11.5 0.2 0.2 10.7 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Amino_oxidase PF01593.24 KZN93250.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Fer4_2 PF12797.7 KZN93250.1 - 0.15 12.2 0.7 0.39 10.9 0.7 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain AbiEii PF08843.11 KZN93253.1 - 3.5e-09 37.0 0.6 5.9e-08 32.9 0.6 2.0 1 1 0 1 1 1 1 Nucleotidyl transferase AbiEii toxin, Type IV TA system AcylCoA_DH_N PF12418.8 KZN93253.1 - 0.14 12.2 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase N terminal Cyclin_N PF00134.23 KZN93254.1 - 1.5e-15 57.0 0.8 4.4e-15 55.5 0.5 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KZN93254.1 - 0.00018 21.6 0.1 0.0026 17.8 0.0 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 KZN93254.1 - 0.065 13.6 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 Cyclin C-terminal domain TFIIB PF00382.19 KZN93254.1 - 1.6 8.8 4.2 2.4 8.2 0.6 2.4 2 0 0 2 2 2 0 Transcription factor TFIIB repeat EAF PF09816.9 KZN93255.1 - 1.8e-21 76.4 0.1 3.5e-21 75.5 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor AMPK1_CBM PF16561.5 KZN93256.1 - 5e-18 65.1 0.8 9.1e-18 64.3 0.8 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase cNMP_binding PF00027.29 KZN93257.1 - 8.1e-41 138.0 0.0 8.2e-21 73.9 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain 2OG-FeII_Oxy_3 PF13640.6 KZN93258.1 - 9.1e-10 39.3 0.0 1.4e-09 38.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KZN93258.1 - 0.053 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Forkhead PF00250.18 KZN93259.1 - 5.1e-17 61.9 0.0 9e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KZN93259.1 - 9.5e-07 29.1 0.0 1.9e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain Aminotran_1_2 PF00155.21 KZN93260.1 - 8.7e-65 219.2 0.0 1.1e-64 218.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KZN93260.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase AMP-binding PF00501.28 KZN93261.1 - 2.6e-39 135.1 0.0 3.7e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KZN93261.1 - 5.1e-11 42.3 2.8 5.9e-11 42.1 1.1 2.0 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KZN93261.1 - 0.00032 21.6 0.0 0.0009 20.2 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peptidase_M16_C PF05193.21 KZN93262.1 - 2e-52 177.9 0.0 9.1e-52 175.7 0.0 2.1 2 1 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KZN93262.1 - 8.4e-41 139.4 0.0 3.6e-39 134.1 0.0 2.2 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Tom22 PF04281.13 KZN93263.1 - 1e-50 171.1 0.7 1.2e-50 170.9 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF4211 PF13926.6 KZN93264.1 - 4.2e-42 143.6 2.0 9.6e-42 142.4 0.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4211) TetR_C_31 PF17940.1 KZN93264.1 - 0.057 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Tir_receptor_C PF07489.11 KZN93264.1 - 0.059 13.3 1.7 0.1 12.5 1.7 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Sugar_tr PF00083.24 KZN93265.1 - 9.7e-99 331.2 21.0 1.1e-98 331.0 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN93265.1 - 1.5e-32 112.9 44.8 7.6e-27 94.2 20.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PGBA_C PF15437.6 KZN93265.1 - 6.8 7.1 11.2 0.41 11.0 6.2 1.5 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal Peptidase_S28 PF05577.12 KZN93266.1 - 0.0013 17.7 0.0 0.0013 17.7 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 AATF-Che1 PF13339.6 KZN93266.1 - 0.076 13.7 0.1 0.098 13.3 0.1 1.3 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor EKLF_TAD1 PF16832.5 KZN93267.1 - 0.069 13.0 0.4 0.18 11.7 0.4 1.7 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 1 Lipase_3 PF01764.25 KZN93268.1 - 1.2e-20 73.8 0.0 1.8e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF1031 PF06275.11 KZN93268.1 - 0.12 12.7 0.1 0.19 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) TauD PF02668.16 KZN93269.1 - 1.4e-34 120.1 0.1 2.2e-34 119.5 0.1 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KZN93269.1 - 0.086 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 CsiD MFS_1 PF07690.16 KZN93270.1 - 2.8e-33 115.3 25.2 2.8e-33 115.3 25.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2530 PF10745.9 KZN93270.1 - 0.023 14.9 1.3 0.023 14.9 1.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) FMO-like PF00743.19 KZN93271.1 - 2.6e-15 55.8 0.0 4.2e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KZN93271.1 - 5e-11 42.4 0.0 1.1e-09 37.9 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KZN93271.1 - 1.4e-07 31.6 0.0 4.3e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KZN93271.1 - 1.8e-06 27.3 0.0 0.00062 19.0 0.0 3.3 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KZN93271.1 - 3.3e-06 27.2 0.1 3.6e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KZN93271.1 - 5.3e-06 25.9 0.3 0.00091 18.6 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KZN93271.1 - 0.0012 18.1 0.0 0.014 14.7 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KZN93271.1 - 0.0079 16.7 0.0 1.4 9.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KZN93271.1 - 0.022 14.4 0.0 6.6 6.2 0.0 2.9 2 1 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KZN93271.1 - 0.073 12.3 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KZN93271.1 - 0.093 11.4 0.2 0.43 9.2 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein DUF2274 PF10038.9 KZN93271.1 - 0.1 13.1 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2274) zf-C3HC4 PF00097.25 KZN93272.1 - 4e-05 23.4 5.8 0.00012 21.9 5.7 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KZN93272.1 - 0.00037 20.4 7.6 0.00037 20.4 7.6 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KZN93272.1 - 0.001 18.8 5.2 0.0026 17.6 5.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 KZN93272.1 - 0.026 14.8 0.7 0.049 13.8 0.7 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Prok-RING_4 PF14447.6 KZN93272.1 - 0.039 13.8 5.6 0.081 12.8 5.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KZN93272.1 - 0.04 13.9 8.0 0.058 13.4 4.4 2.9 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KZN93272.1 - 0.052 13.7 3.2 0.052 13.7 3.2 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KZN93272.1 - 0.055 13.8 9.4 0.6 10.5 10.3 2.3 1 1 1 2 2 2 0 Ring finger domain Rieske PF00355.26 KZN93272.1 - 0.063 13.2 0.2 0.089 12.7 0.2 1.4 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain C1_2 PF03107.16 KZN93272.1 - 0.17 12.3 4.5 0.27 11.6 2.1 2.1 2 0 0 2 2 2 0 C1 domain zf-C3HC4_2 PF13923.6 KZN93272.1 - 0.2 11.6 9.6 1.4 8.9 9.6 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KZN93272.1 - 2.3 8.4 6.8 6.3 7.0 6.4 1.9 1 1 1 2 2 2 0 zinc RING finger of MSL2 DUF3405 PF11885.8 KZN93273.1 - 1.5e-233 776.1 0.6 1.9e-233 775.8 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) DUF1449 PF07290.11 KZN93273.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) Fic PF02661.18 KZN93274.1 - 5.3e-18 65.7 0.0 2.5e-17 63.5 0.0 2.1 2 0 0 2 2 2 1 Fic/DOC family DUF1086 PF06461.11 KZN93274.1 - 0.067 13.1 0.0 0.47 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1086) Arf PF00025.21 KZN93275.1 - 7.7e-79 263.2 0.1 8.9e-79 263.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KZN93275.1 - 6.3e-15 55.1 0.0 7.7e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KZN93275.1 - 3.1e-14 53.2 0.0 4.3e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KZN93275.1 - 3.6e-13 49.4 1.2 2.1e-09 37.1 0.3 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KZN93275.1 - 4.8e-13 49.0 0.0 5.3e-13 48.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KZN93275.1 - 2.2e-10 40.3 0.0 2.6e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KZN93275.1 - 4.3e-06 26.8 0.0 6.4e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KZN93275.1 - 0.012 14.9 0.4 0.027 13.8 0.4 1.7 1 1 0 1 1 1 0 6-phosphofructo-2-kinase SieB PF14163.6 KZN93276.1 - 0.057 12.9 0.5 0.12 11.9 0.5 1.5 1 0 0 1 1 1 0 Super-infection exclusion protein B Ribosomal_L1 PF00687.21 KZN93278.1 - 5.1e-46 157.0 0.6 5.9e-46 156.8 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family WH2 PF02205.20 KZN93280.1 - 8.9e-11 41.3 1.0 2.2e-10 40.0 1.0 1.7 1 0 0 1 1 1 1 WH2 motif LSM PF01423.22 KZN93281.1 - 4.9e-15 55.0 0.2 6.2e-15 54.6 0.2 1.2 1 0 0 1 1 1 1 LSM domain SURF4 PF02077.15 KZN93283.1 - 3.9e-94 315.2 7.8 4.5e-94 315.0 7.8 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.12 KZN93283.1 - 0.091 13.4 18.3 0.19 12.3 4.0 3.0 3 2 0 3 3 3 0 DoxX IU_nuc_hydro PF01156.19 KZN93285.1 - 2.6e-56 191.5 0.0 4.5e-56 190.7 0.0 1.3 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF2249 PF10006.9 KZN93285.1 - 0.045 13.6 0.0 0.14 12.0 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) HLH PF00010.26 KZN93286.1 - 9e-14 51.2 0.1 2.1e-13 50.0 0.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3665 PF12427.8 KZN93286.1 - 5.6 6.7 6.9 24 4.7 0.3 3.3 3 0 0 3 3 3 0 Branched-chain amino acid aminotransferase Fungal_trans PF04082.18 KZN93287.1 - 1.4e-15 57.1 0.1 2.1e-15 56.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN93287.1 - 7.5e-09 35.6 11.0 1.8e-08 34.3 11.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2973 PF11189.8 KZN93287.1 - 0.039 14.0 0.5 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) Fip1 PF05182.13 KZN93289.1 - 0.022 14.3 0.2 7.4 6.2 0.1 2.7 2 0 0 2 2 2 0 Fip1 motif RNA_pol_inhib PF16857.5 KZN93289.1 - 0.16 11.8 0.0 0.88 9.4 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase inhibitor MFS_1 PF07690.16 KZN93290.1 - 1.7e-38 132.4 29.8 1.7e-38 132.4 29.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN93290.1 - 1.1e-13 50.9 0.2 1.1e-13 50.9 0.2 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter DUF3100 PF11299.8 KZN93290.1 - 0.2 11.0 4.9 0.23 10.9 1.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3100) Zn_clus PF00172.18 KZN93291.1 - 5.9e-06 26.3 10.0 9.8e-06 25.6 10.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMO-like PF00743.19 KZN93292.1 - 1.4e-23 83.1 0.0 4.1e-23 81.6 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KZN93292.1 - 2.8e-22 79.4 0.0 2.3e-21 76.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KZN93292.1 - 1.6e-14 53.8 0.0 7e-12 45.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KZN93292.1 - 2.6e-11 43.3 0.1 4.9e-09 35.8 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KZN93292.1 - 5.3e-08 32.5 1.0 0.00064 19.1 0.3 3.2 2 1 1 3 3 3 2 FAD binding domain 2-Hacid_dh_C PF02826.19 KZN93292.1 - 7.8e-07 28.6 0.2 0.0076 15.6 0.1 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KZN93292.1 - 2.9e-06 27.7 0.2 0.035 14.7 0.1 3.0 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN93292.1 - 5.8e-06 26.4 0.0 0.00036 20.7 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain IlvN PF07991.12 KZN93292.1 - 0.00025 20.6 0.4 0.0012 18.4 0.2 2.0 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_9 PF13454.6 KZN93292.1 - 0.00037 20.5 0.1 1.8 8.5 0.0 3.4 2 1 1 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KZN93292.1 - 0.00074 18.7 0.0 0.044 12.8 0.0 2.5 2 0 0 2 2 2 1 Lycopene cyclase protein 3HCDH_N PF02737.18 KZN93292.1 - 0.0015 18.5 0.1 0.055 13.4 0.1 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KZN93292.1 - 0.0021 17.2 0.5 0.014 14.5 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 KZN93292.1 - 0.0032 17.9 0.0 0.09 13.2 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding TrkA_N PF02254.18 KZN93292.1 - 0.0032 17.7 0.1 0.53 10.6 0.0 2.6 3 0 0 3 3 2 1 TrkA-N domain NAD_binding_2 PF03446.15 KZN93292.1 - 0.0034 17.5 0.6 1.6 8.9 0.4 2.4 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase HI0933_like PF03486.14 KZN93292.1 - 0.0086 14.8 0.1 0.46 9.1 0.0 2.5 3 0 0 3 3 3 1 HI0933-like protein Shikimate_DH PF01488.20 KZN93292.1 - 0.014 15.4 0.1 0.42 10.7 0.0 2.5 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 KZN93292.1 - 0.018 14.4 0.1 5.7 6.2 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KZN93292.1 - 0.036 13.1 0.1 8.7 5.3 0.0 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A ApbA PF02558.16 KZN93292.1 - 0.059 13.0 0.1 14 5.3 0.0 2.6 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 KZN93292.1 - 0.1 13.2 0.0 8.4 7.0 0.0 3.1 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent ELFV_dehydrog PF00208.21 KZN93292.1 - 0.16 11.7 0.4 0.28 10.9 0.4 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase UDPG_MGDP_dh_N PF03721.14 KZN93292.1 - 0.2 11.2 0.4 1.8 8.1 0.0 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF4408 PF14364.6 KZN93294.1 - 0.0042 16.8 0.5 0.011 15.4 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4408) DUF4781 PF16013.5 KZN93294.1 - 0.31 9.8 3.8 0.37 9.6 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) GFO_IDH_MocA PF01408.22 KZN93295.1 - 3.7e-16 60.0 0.0 5.9e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Abhydrolase_6 PF12697.7 KZN93297.1 - 2.3e-08 34.9 1.1 3.2e-08 34.4 1.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KZN93298.1 - 9e-19 68.2 0.0 1.3e-18 67.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KZN93298.1 - 8.7e-07 28.6 0.0 0.0023 17.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KZN93298.1 - 6.8e-06 25.2 0.0 9.9e-06 24.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KZN93298.1 - 2.8e-05 23.3 0.0 5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase COesterase PF00135.28 KZN93298.1 - 0.00026 20.0 0.0 0.00039 19.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Esterase PF00756.20 KZN93298.1 - 0.00042 20.0 0.0 0.00091 18.9 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KZN93298.1 - 0.0044 16.3 0.0 0.8 8.9 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 AXE1 PF05448.12 KZN93298.1 - 0.086 11.5 0.0 0.65 8.6 0.0 1.9 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) FAD_binding_4 PF01565.23 KZN93299.1 - 9e-23 80.5 1.9 1.8e-22 79.6 1.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KZN93299.1 - 2e-05 24.6 0.0 5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like FAD-oxidase_C PF02913.19 KZN93299.1 - 0.043 13.4 0.0 0.41 10.2 0.0 2.1 2 0 0 2 2 2 0 FAD linked oxidases, C-terminal domain NAD_binding_10 PF13460.6 KZN93300.1 - 4.9e-11 42.8 0.0 1.1e-10 41.7 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 KZN93300.1 - 0.00016 21.7 0.0 0.00028 21.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KZN93300.1 - 0.00033 21.1 0.0 0.00066 20.1 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding F420_oxidored PF03807.17 KZN93300.1 - 0.022 15.3 0.0 0.05 14.2 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF4695 PF15766.5 KZN93300.1 - 0.034 14.4 0.0 0.87 9.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4695) Sacchrp_dh_NADP PF03435.18 KZN93300.1 - 0.072 13.4 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Stealth_CR3 PF17102.5 KZN93300.1 - 0.18 11.8 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Stealth protein CR3, conserved region 3 Fungal_trans_2 PF11951.8 KZN93301.1 - 5.6e-21 74.8 10.0 2.2e-20 72.9 10.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN93301.1 - 2.1e-08 34.1 6.9 4.9e-08 33.0 6.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FA_hydroxylase PF04116.13 KZN93302.1 - 5.2e-21 75.4 10.9 5.2e-21 75.4 10.9 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF5045 PF16464.5 KZN93302.1 - 0.27 11.6 0.8 0.55 10.6 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5045) 4HBT PF03061.22 KZN93303.1 - 5.3e-12 45.9 0.0 8.3e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily CLASP_N PF12348.8 KZN93304.1 - 1.4e-149 495.8 0.1 6.3e-88 294.1 0.0 2.3 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 KZN93304.1 - 5.1e-09 35.6 0.0 0.035 14.3 0.0 5.9 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 KZN93304.1 - 1.2e-07 31.9 0.0 0.016 15.2 0.0 4.3 2 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KZN93304.1 - 0.0078 16.6 1.1 16 6.0 0.1 4.3 3 1 0 4 4 4 1 HEAT repeats Condensin2nSMC PF12422.8 KZN93304.1 - 0.014 15.6 0.0 2.2 8.5 0.0 3.3 4 0 0 4 4 4 0 Condensin II non structural maintenance of chromosomes subunit HEAT_EZ PF13513.6 KZN93304.1 - 0.017 15.7 0.1 17 6.0 0.0 3.5 3 0 0 3 3 3 0 HEAT-like repeat Fanconi_A_N PF15865.5 KZN93304.1 - 0.063 12.7 0.4 7.8 5.8 0.1 2.5 2 0 0 2 2 2 0 Fanconi anaemia group A protein N terminus Adaptin_N PF01602.20 KZN93304.1 - 0.39 9.2 1.5 1 7.9 0.1 2.3 2 0 0 2 2 2 0 Adaptin N terminal region DUF3361 PF11841.8 KZN93304.1 - 0.69 9.8 3.7 0.32 10.9 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) BSP PF04450.12 KZN93305.1 - 1.4e-76 256.9 0.0 1.6e-76 256.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria dsrm PF00035.26 KZN93306.1 - 2.8e-06 27.9 0.2 9.7e-05 23.0 0.0 2.9 3 0 0 3 3 3 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 KZN93306.1 - 4.7e-06 27.2 0.0 2.5e-05 24.9 0.0 2.1 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KZN93306.1 - 5.8e-06 26.5 0.0 0.00039 20.6 0.1 2.2 2 0 0 2 2 2 1 Ribonuclease-III-like PfkB PF00294.24 KZN93308.1 - 7e-12 45.3 0.0 1.3e-11 44.4 0.0 1.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase CAP_N PF01213.19 KZN93309.1 - 4.5e-112 374.6 10.5 2.6e-90 303.1 0.2 2.5 2 1 1 3 3 3 2 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KZN93309.1 - 2e-58 196.4 0.2 2.7e-58 196.0 0.2 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal HAUS-augmin3 PF14932.6 KZN93309.1 - 0.24 10.9 0.1 0.43 10.1 0.1 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 TBCC PF07986.12 KZN93309.1 - 1.2 8.9 4.4 5.5 6.7 3.3 2.1 1 1 1 2 2 2 0 Tubulin binding cofactor C DUF4210 PF13915.6 KZN93310.1 - 1e-31 109.3 1.0 1.9e-31 108.4 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 KZN93310.1 - 1.1e-23 83.1 0.3 2.9e-23 81.8 0.3 1.8 1 0 0 1 1 1 1 Chromosome segregation during meiosis rRNA_processing PF08524.11 KZN93311.1 - 0.014 15.4 25.6 0.083 12.9 25.6 1.9 1 1 0 1 1 1 0 rRNA processing RR_TM4-6 PF06459.12 KZN93311.1 - 2.3 8.0 12.0 3 7.6 12.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 KZN93311.1 - 9 4.9 7.5 11 4.6 7.5 1.1 1 0 0 1 1 1 0 Presenilin Sec5 PF15469.6 KZN93312.1 - 2e-36 125.6 0.0 5.6e-36 124.1 0.0 1.8 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.11 KZN93312.1 - 3e-05 24.0 0.0 0.0001 22.3 0.0 2.0 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 KZN93312.1 - 0.078 13.1 0.0 0.3 11.2 0.0 2.0 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Iso_dh PF00180.20 KZN93313.1 - 1e-100 337.3 0.0 1.2e-100 337.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HHH_2 PF12826.7 KZN93313.1 - 0.0085 16.2 0.2 0.32 11.1 0.0 2.6 3 0 0 3 3 3 1 Helix-hairpin-helix motif Eaf7 PF07904.13 KZN93314.1 - 4.8e-29 100.8 1.2 6.1e-29 100.5 0.0 1.8 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 CDC45 PF02724.14 KZN93314.1 - 2.9 6.1 9.7 4.2 5.5 9.7 1.4 1 0 0 1 1 1 0 CDC45-like protein GCP_C_terminal PF04130.13 KZN93315.1 - 1.7e-65 221.5 0.0 2.4e-65 221.0 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KZN93315.1 - 3.4e-53 181.2 0.0 9.5e-53 179.8 0.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal Mo-co_dimer PF03404.16 KZN93316.1 - 4.7e-59 198.3 0.2 9.3e-59 197.4 0.2 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 KZN93316.1 - 3.5e-52 176.5 0.0 6.6e-52 175.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 KZN93316.1 - 2.6e-35 120.7 0.0 4.5e-35 120.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KZN93316.1 - 6.2e-31 107.3 0.1 1.2e-30 106.3 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 KZN93316.1 - 1.1e-15 57.5 0.0 2.3e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KZN93316.1 - 0.0027 17.8 0.0 0.77 9.9 0.0 2.4 1 1 0 2 2 2 2 Ferric reductase NAD binding domain LysM PF01476.20 KZN93317.1 - 7.5e-18 64.3 0.0 2.2e-06 27.6 0.0 4.1 4 0 0 4 4 4 3 LysM domain NLPC_P60 PF00877.19 KZN93317.1 - 0.0057 16.7 1.3 8.5 6.5 0.0 3.9 4 0 0 4 4 4 1 NlpC/P60 family ETM PF17577.2 KZN93317.1 - 0.008 16.7 1.4 22 5.7 0.1 3.3 3 0 0 3 3 3 2 ECORI-T site HTH_Tnp_1 PF01527.20 KZN93317.1 - 0.16 12.3 0.0 51 4.3 0.0 2.8 3 0 0 3 3 3 0 Transposase PP2C PF00481.21 KZN93317.1 - 0.22 11.1 0.1 21 4.6 0.0 3.1 3 0 0 3 3 3 0 Protein phosphatase 2C MULE PF10551.9 KZN93318.1 - 1.7e-05 25.1 0.0 3.6e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain DUF5549 PF17703.1 KZN93318.1 - 0.28 10.8 4.8 0.47 10.1 4.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5549) Spem1 PF15670.5 KZN93320.1 - 0.069 12.7 3.4 6.2 6.3 1.6 2.1 2 0 0 2 2 2 0 Spermatid maturation protein 1 Zn_ribbon_17 PF17120.5 KZN93320.1 - 0.59 9.8 14.0 1.3 8.7 14.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 KZN93320.1 - 0.74 10.2 18.4 1.5 9.3 18.4 1.5 1 0 0 1 1 1 0 Ring finger domain RINGv PF12906.7 KZN93320.1 - 8.9 6.5 17.9 17 5.6 17.9 1.5 1 0 0 1 1 1 0 RING-variant domain Pkinase_Tyr PF07714.17 KZN93322.1 - 0.0017 17.7 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KZN93322.1 - 0.043 13.2 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain DUF3435 PF11917.8 KZN93323.1 - 1.2e-159 531.8 0.4 2.9e-159 530.5 0.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) zf-C2H2_4 PF13894.6 KZN93323.1 - 0.0029 18.3 2.9 0.018 15.8 0.4 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KZN93323.1 - 0.16 12.5 2.1 0.6 10.7 0.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type OmpH PF03938.14 KZN93323.1 - 4.7 7.5 11.0 48 4.3 9.4 2.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Alginate_lyase PF05426.12 KZN93324.1 - 3.9e-20 72.5 1.4 7.6e-20 71.6 1.4 1.4 1 1 0 1 1 1 1 Alginate lyase Dioxygenase_C PF00775.21 KZN93325.1 - 3.3e-41 140.7 0.0 4.5e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KZN93325.1 - 2.4e-29 101.0 0.0 6e-29 99.7 0.0 1.7 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Fe-ADH PF00465.19 KZN93326.1 - 8.6e-77 258.4 0.9 9.9e-77 258.2 0.9 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KZN93326.1 - 8.1e-14 51.9 0.2 1.1e-13 51.4 0.2 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase UPF0261 PF06792.11 KZN93326.1 - 0.12 11.3 0.4 0.17 10.8 0.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) IMS_C PF11799.8 KZN93326.1 - 0.12 13.0 0.0 1.6 9.4 0.0 2.4 2 1 0 3 3 3 0 impB/mucB/samB family C-terminal domain FAD_binding_3 PF01494.19 KZN93327.1 - 3.2e-69 233.8 0.0 2.4e-68 231.0 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KZN93327.1 - 5.3e-31 107.9 0.0 9.8e-31 107.0 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.10 KZN93327.1 - 0.00014 21.0 0.0 0.00027 20.1 0.0 1.5 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.14 KZN93327.1 - 0.1 11.8 0.0 0.28 10.4 0.0 1.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN93327.1 - 0.16 12.2 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HEAT PF02985.22 KZN93328.1 - 1.3e-14 53.0 10.1 0.0015 18.6 0.1 8.6 9 0 0 9 9 8 4 HEAT repeat HEAT_EZ PF13513.6 KZN93328.1 - 7.9e-14 51.8 0.7 6.2e-10 39.4 0.0 6.7 6 1 1 7 7 7 2 HEAT-like repeat IBN_N PF03810.19 KZN93328.1 - 2.1e-07 30.8 5.9 1.6e-06 27.9 0.7 4.0 4 0 0 4 4 4 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KZN93328.1 - 1.6e-05 25.2 7.5 0.091 13.2 0.1 5.5 3 2 3 6 6 6 3 HEAT repeats CLASP_N PF12348.8 KZN93328.1 - 3.3e-05 23.6 0.2 0.069 12.7 0.1 4.1 2 1 3 5 5 5 1 CLASP N terminal DRIM PF07539.12 KZN93328.1 - 0.00022 19.7 0.5 8.9 4.5 0.0 4.3 4 0 0 4 4 4 2 Down-regulated in metastasis Dopey_N PF04118.14 KZN93328.1 - 0.00037 19.7 0.3 0.02 14.0 0.1 2.6 2 0 0 2 2 2 1 Dopey, N-terminal DUF3385 PF11865.8 KZN93328.1 - 0.00038 20.4 0.1 0.88 9.5 0.1 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 KZN93328.1 - 0.00071 20.1 0.2 8.6 7.0 0.0 4.7 4 1 0 4 4 4 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KZN93328.1 - 0.046 12.3 0.7 2.6 6.5 0.0 3.2 2 1 0 3 3 3 0 Adaptin N terminal region Cse1 PF08506.10 KZN93328.1 - 0.051 12.4 0.2 0.38 9.5 0.1 2.4 2 1 2 4 4 4 0 Cse1 Sec7_N PF12783.7 KZN93328.1 - 0.067 13.1 0.0 1.1 9.2 0.0 2.6 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT_PBS PF03130.16 KZN93328.1 - 0.12 13.1 1.3 72 4.5 0.0 4.6 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat Arm PF00514.23 KZN93328.1 - 4.7 7.4 7.9 11 6.2 0.3 4.3 5 0 0 5 5 4 0 Armadillo/beta-catenin-like repeat Ribosomal_S8 PF00410.19 KZN93329.1 - 2e-21 76.3 0.0 2.9e-21 75.7 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 His_Phos_1 PF00300.22 KZN93330.1 - 1.6e-13 50.8 0.0 1e-07 31.9 0.0 2.8 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) ubiquitin PF00240.23 KZN93331.1 - 3.7e-09 36.2 0.0 1.3e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family DUF2407 PF10302.9 KZN93331.1 - 0.0021 18.6 0.1 0.0073 16.8 0.0 2.0 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain FAM35_C PF15793.5 KZN93331.1 - 0.12 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein family FAM35, C-terminal PS_Dcarbxylase PF02666.15 KZN93332.1 - 2.6e-76 255.7 0.0 1.6e-75 253.1 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Mem_trans PF03547.18 KZN93333.1 - 4.7e-54 183.3 5.5 3.6e-53 180.3 5.5 1.9 1 1 0 1 1 1 1 Membrane transport protein Glyco_transf_90 PF05686.12 KZN93334.1 - 1.1e-19 70.7 6.1 1.4e-17 63.8 1.6 3.6 3 1 0 3 3 3 2 Glycosyl transferase family 90 Taeniidae_ag PF05596.11 KZN93334.1 - 0.012 15.6 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Taeniidae antigen Cu-oxidase_3 PF07732.15 KZN93335.1 - 3.5e-37 127.0 0.2 2.9e-34 117.6 0.0 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KZN93335.1 - 1.2e-29 102.8 3.5 1.2e-29 102.8 3.5 3.4 4 1 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 KZN93335.1 - 2.1e-17 63.7 0.3 1.1e-16 61.3 0.0 2.3 3 0 0 3 3 3 1 Multicopper oxidase Phosphoesterase PF04185.14 KZN93336.1 - 9.2e-71 238.9 5.9 1.5e-70 238.2 5.9 1.3 1 0 0 1 1 1 1 Phosphoesterase family GPI-anchored PF10342.9 KZN93337.1 - 0.008 16.9 0.1 0.016 15.9 0.0 1.5 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DM13 PF10517.9 KZN93337.1 - 0.085 13.5 0.0 0.11 13.1 0.0 1.3 1 0 0 1 1 1 0 Electron transfer DM13 p450 PF00067.22 KZN93338.1 - 2.4e-51 174.9 0.0 3.1e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Choline_kinase PF01633.20 KZN93339.1 - 7.8e-62 208.6 0.0 3.1e-61 206.7 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 KZN93339.1 - 6.5e-16 57.7 0.0 1.2e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 KZN93339.1 - 5.4e-05 23.2 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Peptidase_C12 PF01088.21 KZN93340.1 - 6.1e-71 238.5 0.0 7.7e-71 238.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KZN93340.1 - 3.9e-09 36.3 0.0 8.7e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Zn_clus PF00172.18 KZN93341.1 - 2.2e-07 30.9 16.1 3.6e-07 30.2 16.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KZN93341.1 - 9.6e-06 24.6 4.2 1e-05 24.5 3.3 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain CVNH PF08881.10 KZN93342.1 - 4.6e-27 94.7 0.2 5.1e-27 94.5 0.2 1.0 1 0 0 1 1 1 1 CVNH domain HEAT_EZ PF13513.6 KZN93343.1 - 4.2e-36 122.9 0.6 4.1e-15 55.9 0.1 8.4 8 0 0 8 8 8 5 HEAT-like repeat HEAT PF02985.22 KZN93343.1 - 1.2e-17 62.5 21.0 0.0012 18.9 0.0 11.4 13 0 0 13 13 13 4 HEAT repeat HEAT_2 PF13646.6 KZN93343.1 - 1.7e-16 60.4 0.3 0.00052 20.3 0.0 8.0 5 3 2 8 8 8 3 HEAT repeats Cnd1 PF12717.7 KZN93343.1 - 3.1e-12 46.9 0.5 4.6e-06 26.8 0.0 4.5 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KZN93343.1 - 2.9e-09 37.4 0.1 0.19 12.4 0.0 6.2 4 3 3 7 7 7 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KZN93343.1 - 3.6e-09 35.7 0.1 0.0049 15.5 0.0 3.5 3 1 0 4 4 4 2 Adaptin N terminal region MMS19_C PF12460.8 KZN93343.1 - 2.3e-06 27.0 6.2 1.4 8.0 0.2 6.1 5 1 1 6 6 6 3 RNAPII transcription regulator C-terminal IBN_N PF03810.19 KZN93343.1 - 6.4e-06 26.0 0.2 0.0039 17.1 0.0 3.9 2 1 0 2 2 2 1 Importin-beta N-terminal domain DRIM PF07539.12 KZN93343.1 - 5.1e-05 21.8 0.0 0.35 9.1 0.0 3.2 3 0 0 3 3 3 2 Down-regulated in metastasis CLASP_N PF12348.8 KZN93343.1 - 0.00095 18.8 0.9 5.6 6.4 0.0 5.3 4 3 1 5 5 5 1 CLASP N terminal HEAT_PBS PF03130.16 KZN93343.1 - 0.0013 19.2 1.2 18 6.3 0.0 5.4 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat RIX1 PF08167.12 KZN93343.1 - 0.0022 17.8 0.1 6.6 6.4 0.0 4.1 5 0 0 5 5 5 1 rRNA processing/ribosome biogenesis DUF3437 PF11919.8 KZN93343.1 - 0.015 15.2 0.2 2.8 7.9 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3437) Dopey_N PF04118.14 KZN93343.1 - 0.017 14.3 0.3 4.5 6.3 0.0 3.0 3 0 0 3 3 3 0 Dopey, N-terminal Proteasom_PSMB PF10508.9 KZN93343.1 - 0.018 13.6 0.0 0.046 12.2 0.0 1.7 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit Arm PF00514.23 KZN93343.1 - 0.022 14.8 1.6 7.4 6.8 0.1 4.5 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat TIP120 PF08623.10 KZN93343.1 - 0.069 12.9 0.0 10 5.9 0.0 3.6 4 0 0 4 4 4 0 TATA-binding protein interacting (TIP20) Tti2 PF10521.9 KZN93343.1 - 0.46 10.0 1.9 40 3.6 0.0 3.4 3 1 0 3 3 3 0 Tti2 family Syja_N PF02383.18 KZN93344.1 - 1e-92 310.9 0.0 1.5e-92 310.3 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 KZN93344.1 - 4.5e-38 129.5 0.0 9.1e-38 128.5 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase DUF3246 PF11596.8 KZN93344.1 - 0.4 10.1 8.4 0.059 12.8 3.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Mg_trans_NIPA PF05653.14 KZN93345.1 - 1.3e-103 346.2 18.2 1.5e-103 345.9 18.2 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KZN93345.1 - 0.00015 21.9 37.1 0.0004 20.6 9.0 3.2 3 0 0 3 3 3 3 EamA-like transporter family DUF2420 PF10336.9 KZN93346.1 - 7.6e-19 67.7 0.0 1.6e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Adap_comp_sub PF00928.21 KZN93347.1 - 6.6e-18 65.0 0.0 9.4e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KZN93347.1 - 1.5e-07 31.4 0.1 2.6e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KZN93347.1 - 0.0012 18.4 0.0 0.0044 16.5 0.0 1.8 1 1 0 1 1 1 1 Muniscin C-terminal mu homology domain RPM2 PF08579.11 KZN93347.1 - 0.0037 17.7 0.2 0.0072 16.7 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) Fungal_trans PF04082.18 KZN93348.1 - 1e-22 80.5 0.3 2.6e-22 79.2 0.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN93348.1 - 3.1e-05 24.0 16.2 9.1e-05 22.5 16.2 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3782 PF12644.7 KZN93348.1 - 0.047 13.9 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) OMPdecase PF00215.24 KZN93350.1 - 0.00013 21.7 0.0 0.00047 19.8 0.0 1.8 2 0 0 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Cyt-b5 PF00173.28 KZN93351.1 - 2.6e-18 65.9 0.2 2.6e-18 65.9 0.2 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KZN93351.1 - 1.8e-12 47.7 19.1 1.8e-12 47.7 19.1 1.8 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 KZN93351.1 - 0.0085 16.3 0.2 0.019 15.2 0.2 1.5 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region ATP-synt_I PF03899.15 KZN93351.1 - 0.012 16.0 4.2 0.26 11.7 0.1 2.2 2 0 0 2 2 2 0 ATP synthase I chain COX14 PF14880.6 KZN93351.1 - 0.2 11.5 1.3 1.2 9.1 0.1 2.3 2 0 0 2 2 2 0 Cytochrome oxidase c assembly RRM_1 PF00076.22 KZN93352.1 - 1.2e-44 150.0 1.6 1.8e-22 78.9 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KZN93352.1 - 1.2e-23 84.0 0.1 4e-23 82.3 0.1 2.0 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 KZN93352.1 - 9.6e-05 22.2 0.0 0.02 14.8 0.0 3.0 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KZN93352.1 - 0.0044 17.0 0.1 0.049 13.7 0.0 2.5 2 0 0 2 2 2 1 RNA binding motif RRM_5 PF13893.6 KZN93352.1 - 0.0049 16.5 0.0 0.014 15.0 0.0 1.8 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KZN93352.1 - 0.013 15.7 0.3 1.1 9.4 0.3 3.1 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Limkain-b1 PF11608.8 KZN93352.1 - 0.019 15.0 0.2 0.56 10.3 0.0 3.0 3 0 0 3 3 3 0 Limkain b1 RRM_7 PF16367.5 KZN93352.1 - 0.023 14.8 0.0 0.33 11.1 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif PP2C PF00481.21 KZN93353.1 - 3.3e-32 112.1 0.0 1.5e-26 93.6 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KZN93353.1 - 0.02 14.5 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein phosphatase 2C CDP-OH_P_transf PF01066.21 KZN93354.1 - 8.4e-13 48.9 0.5 8.4e-13 48.9 0.5 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Sugar_tr PF00083.24 KZN93355.1 - 2.3e-116 389.3 27.8 2.6e-116 389.1 27.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN93355.1 - 1.4e-21 76.9 48.4 1.2e-17 63.9 23.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DnaJ PF00226.31 KZN93358.1 - 1.6e-16 60.2 0.5 4.2e-16 58.8 0.5 1.7 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 KZN93358.1 - 7.7e-10 38.4 0.0 9e-09 34.9 0.0 2.1 1 1 0 1 1 1 1 Sec63 Brl domain E1-E2_ATPase PF00122.20 KZN93359.1 - 1.6e-33 115.7 16.0 1.3e-27 96.5 0.0 3.1 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KZN93359.1 - 7.1e-27 94.3 9.9 7.1e-27 94.3 9.9 2.7 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 KZN93359.1 - 1.3e-18 66.4 0.0 3.1e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KZN93359.1 - 6e-17 62.6 0.6 5.6e-13 49.7 0.3 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KZN93359.1 - 3.4e-15 55.9 0.0 8.6e-15 54.6 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KZN93359.1 - 3.8e-05 23.5 0.5 0.00091 19.0 0.6 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 KZN93360.1 - 5.6e-33 114.3 56.6 3.8e-32 111.6 50.4 3.3 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KZN93360.1 - 4.9e-20 71.5 18.3 7.4e-20 70.9 18.3 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KZN93360.1 - 6.2e-14 51.7 3.1 6.2e-14 51.7 3.1 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KZN93360.1 - 1.3 7.3 13.8 6.2 5.0 10.0 3.0 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Zn_clus PF00172.18 KZN93361.1 - 3e-08 33.7 13.9 5.8e-08 32.7 13.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MatE PF01554.18 KZN93363.1 - 9.2e-46 155.4 19.6 2e-26 92.6 3.6 2.6 2 1 1 3 3 3 2 MatE Polysacc_synt_C PF14667.6 KZN93363.1 - 0.046 13.8 28.2 0.18 11.9 15.6 3.6 3 1 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain DUF2269 PF10027.9 KZN93363.1 - 5.5 7.0 12.4 0.077 13.0 1.7 3.0 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2269) MFS_1 PF07690.16 KZN93364.1 - 8.4e-36 123.6 40.3 3.6e-32 111.7 29.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN93364.1 - 7.5e-13 48.1 7.7 7.5e-13 48.1 7.7 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter ArsA_HSP20 PF17886.1 KZN93365.1 - 0.0091 15.5 0.2 0.048 13.2 0.2 2.2 1 1 0 1 1 1 1 HSP20-like domain found in ArsA HSP20 PF00011.21 KZN93365.1 - 0.1 12.8 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 Hsp20/alpha crystallin family Pyr_redox_2 PF07992.14 KZN93366.1 - 4.4e-34 118.0 0.0 8.2e-32 110.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KZN93366.1 - 1.7e-08 34.9 0.0 8.3e-08 32.7 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NLPC_P60 PF00877.19 KZN93367.1 - 4.3e-18 65.3 0.0 8.5e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 NlpC/P60 family Amidase_5 PF05382.13 KZN93367.1 - 0.00044 20.2 0.3 0.0011 18.9 0.1 1.7 1 1 0 1 1 1 1 Bacteriophage peptidoglycan hydrolase SH3_3 PF08239.11 KZN93367.1 - 0.0023 18.2 0.0 0.0041 17.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain DUF1175 PF06672.11 KZN93367.1 - 0.039 13.6 0.0 6 6.5 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1175) SH3_4 PF06347.13 KZN93367.1 - 0.071 12.9 0.0 0.25 11.2 0.0 1.9 3 0 0 3 3 3 0 Bacterial SH3 domain Aa_trans PF01490.18 KZN93369.1 - 3e-24 85.5 34.0 3.6e-24 85.2 34.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Amidase PF01425.21 KZN93370.1 - 1.3e-87 294.6 0.0 1.8e-87 294.2 0.0 1.2 1 0 0 1 1 1 1 Amidase adh_short_C2 PF13561.6 KZN93371.1 - 1.5e-43 149.1 0.5 1.8e-43 148.8 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN93371.1 - 2.3e-40 138.1 0.5 3e-40 137.8 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN93371.1 - 3.7e-10 40.0 0.2 5.4e-10 39.5 0.2 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KZN93371.1 - 0.034 13.5 0.0 0.51 9.7 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Sod_Fe_N PF00081.22 KZN93372.1 - 2e-33 114.7 1.8 2e-33 114.7 1.8 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.18 KZN93372.1 - 2.4e-31 107.9 0.4 1.1e-30 105.7 0.0 2.0 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain SR-25 PF10500.9 KZN93373.1 - 3.3 7.3 5.6 4.5 6.8 5.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TPR_2 PF07719.17 KZN93374.1 - 4.3e-09 35.8 12.7 0.0011 18.9 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 KZN93374.1 - 1.3e-08 34.2 4.6 0.0043 16.8 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 KZN93374.1 - 8e-07 29.5 0.5 0.14 12.7 0.0 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KZN93374.1 - 2.7e-05 24.0 2.2 0.53 10.6 0.0 5.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 KZN93374.1 - 0.0003 21.0 2.7 0.028 14.7 0.2 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KZN93374.1 - 0.00092 19.8 7.2 12 6.7 0.2 5.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 KZN93374.1 - 0.0019 18.9 8.7 0.89 10.5 0.1 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 KZN93374.1 - 0.031 14.1 2.0 12 5.9 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KZN93374.1 - 0.035 14.7 2.1 0.74 10.6 0.6 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KZN93374.1 - 0.09 13.0 0.0 5.6 7.3 0.0 3.3 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Glyco_hydro_47 PF01532.20 KZN93378.1 - 7.4e-141 470.2 0.0 8.5e-141 470.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TPKR_C2 PF16920.5 KZN93378.1 - 0.12 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Tyrosine-protein kinase receptor C2 Ig-like domain GFA PF04828.14 KZN93379.1 - 0.00013 22.3 0.1 0.00013 22.3 0.1 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DUF4504 PF14953.6 KZN93379.1 - 0.076 12.4 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4504) Histidinol_dh PF00815.20 KZN93380.1 - 3.4e-159 530.2 3.1 4.8e-159 529.8 3.1 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 KZN93380.1 - 4e-23 81.0 0.1 8.5e-23 80.0 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 KZN93380.1 - 2.7e-14 53.4 0.2 6.6e-14 52.1 0.2 1.6 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase SIP PF04954.13 KZN93380.1 - 0.041 14.4 0.4 1.7 9.2 0.2 2.6 2 0 0 2 2 2 0 Siderophore-interacting protein CIAPIN1 PF05093.13 KZN93381.1 - 1.2e-42 144.5 3.5 2.3e-42 143.6 3.5 1.5 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 KZN93381.1 - 1.5e-37 128.7 0.1 2.1e-37 128.3 0.1 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus DUF1280 PF06918.14 KZN93382.1 - 0.059 12.9 0.2 0.093 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1280) Cro PF09048.10 KZN93382.1 - 0.16 12.0 0.1 0.41 10.7 0.1 1.6 1 0 0 1 1 1 0 Cro zf-C2H2_4 PF13894.6 KZN93383.1 - 9.5e-05 22.9 31.4 0.85 10.6 0.5 7.8 7 1 0 7 7 7 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KZN93383.1 - 0.0063 16.9 25.0 2.9 8.5 0.1 6.8 7 0 0 7 7 7 3 Zinc finger, C2H2 type DUF1403 PF07183.11 KZN93383.1 - 0.062 12.9 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1403) Clusterin PF01093.17 KZN93383.1 - 0.063 12.3 0.4 0.14 11.2 0.4 1.6 1 1 0 1 1 1 0 Clusterin FOXP-CC PF16159.5 KZN93383.1 - 0.15 12.7 7.1 2.2 9.0 0.2 4.0 4 0 0 4 4 4 0 FOXP coiled-coil domain zf-Di19 PF05605.12 KZN93383.1 - 0.26 11.6 19.2 0.28 11.5 0.6 5.0 4 1 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KZN93383.1 - 0.29 11.5 3.4 1.3 9.4 0.5 3.2 2 2 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 KZN93383.1 - 0.5 10.9 16.5 68 4.1 1.0 6.9 6 2 0 6 6 6 0 Zinc-finger double domain zf-met PF12874.7 KZN93383.1 - 0.99 9.9 7.5 9.3 6.8 0.4 4.3 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Utp11 PF03998.13 KZN93384.1 - 3.5e-60 204.0 27.5 4e-60 203.8 27.5 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 KZN93384.1 - 0.04 13.2 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Cmc1 PF08583.10 KZN93385.1 - 3.4e-15 55.8 2.9 3.4e-15 55.8 2.9 1.6 1 1 1 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 KZN93385.1 - 0.0014 18.6 0.7 0.0022 17.9 0.7 1.4 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, TFIID-31kDa PF02291.15 KZN93386.1 - 2.5e-45 153.5 0.0 3.3e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit LNS2 PF08235.13 KZN93387.1 - 3.4e-96 321.1 0.0 4.6e-96 320.7 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KZN93387.1 - 1.3e-40 137.5 0.0 2.7e-40 136.5 0.0 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 KZN93387.1 - 0.004 16.8 0.0 0.075 12.6 0.0 2.6 3 0 0 3 3 3 1 HAD superfamily, subfamily IIIB (Acid phosphatase) WRNPLPNID PF15017.6 KZN93387.1 - 0.18 12.7 14.0 0.54 11.2 14.0 1.9 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box CDC45 PF02724.14 KZN93387.1 - 6.7 4.9 7.4 9.7 4.3 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein fn3 PF00041.21 KZN93388.1 - 5.5e-07 29.8 0.0 1.4e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain Thg1 PF04446.12 KZN93389.1 - 4e-53 178.7 0.0 5.6e-53 178.2 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 KZN93389.1 - 2.4e-52 176.2 0.9 3.2e-52 175.8 0.9 1.1 1 0 0 1 1 1 1 Thg1 C terminal domain DUF4114 PF13448.6 KZN93390.1 - 0.013 16.3 0.0 0.033 15.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4114) ESM4 PF15952.5 KZN93390.1 - 6.3 7.2 10.9 11 6.4 10.9 1.5 1 1 0 1 1 1 0 Enhancer of split M4 family WD40 PF00400.32 KZN93391.1 - 5e-14 52.5 0.3 0.00096 19.9 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Methyltransf_23 PF13489.6 KZN93392.1 - 2.6e-17 63.1 0.0 4.5e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN93392.1 - 8e-10 39.3 0.0 2.3e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN93392.1 - 4.3e-08 33.8 0.0 1.1e-07 32.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN93392.1 - 1.9e-06 28.4 0.0 4.6e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN93392.1 - 3.2e-05 23.8 0.0 9.5e-05 22.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KZN93392.1 - 0.00015 22.0 0.0 0.00033 20.8 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KZN93392.1 - 0.0041 16.5 0.0 0.063 12.6 0.0 2.3 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KZN93392.1 - 0.0042 16.5 0.0 0.0075 15.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KZN93392.1 - 0.005 16.4 0.0 0.0095 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KZN93392.1 - 0.021 14.3 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.20 KZN93392.1 - 0.14 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase WD40 PF00400.32 KZN93393.1 - 4.6e-13 49.4 11.1 3.6e-05 24.4 0.3 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN93393.1 - 8e-11 42.1 0.4 0.0051 17.1 0.0 4.0 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KZN93393.1 - 1.6e-05 24.9 0.1 0.07 13.0 0.0 3.0 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KZN93393.1 - 0.037 12.6 0.0 0.11 11.1 0.0 1.8 2 0 0 2 2 2 0 Cytochrome D1 heme domain RNA_pol_Rpb1_1 PF04997.12 KZN93394.1 - 6.2e-112 374.0 0.0 9.8e-112 373.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KZN93394.1 - 6.6e-103 343.8 0.1 1.1e-102 343.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KZN93394.1 - 2.2e-74 249.2 0.0 4.9e-74 248.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KZN93394.1 - 3.9e-64 216.0 1.8 8.3e-64 214.9 1.2 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 KZN93394.1 - 4.3e-45 153.0 9.0 2.4e-44 150.6 7.1 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 KZN93394.1 - 8.2e-45 152.5 0.0 2.1e-44 151.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KZN93394.1 - 6.6e-38 129.0 0.1 1.8e-37 127.6 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 KZN93394.1 - 1.3e-17 63.2 194.0 0.0015 18.8 0.1 14.0 11 3 2 13 13 13 11 RNA polymerase Rpb1 C-terminal repeat YorP PF09629.10 KZN93394.1 - 0.091 13.0 0.0 1.6 9.0 0.0 2.6 3 0 0 3 3 3 0 YorP protein Sel1 PF08238.12 KZN93395.1 - 9.6e-36 121.4 36.4 1.6e-05 25.4 0.4 11.7 11 1 1 12 12 12 8 Sel1 repeat TPR_7 PF13176.6 KZN93395.1 - 0.0056 16.6 4.9 14 6.0 0.0 5.6 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KZN93395.1 - 0.26 11.6 3.0 18 5.9 0.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KZN93395.1 - 0.47 11.4 5.1 24 6.1 1.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Zn_clus PF00172.18 KZN93396.1 - 9.9e-06 25.6 13.8 1.8e-05 24.7 13.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mei5 PF10376.9 KZN93396.1 - 0.12 12.3 0.1 0.85 9.4 0.1 2.2 1 1 0 1 1 1 0 Double-strand recombination repair protein Nup54 PF13874.6 KZN93396.1 - 0.12 12.4 0.0 16 5.6 0.0 2.4 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Amidase PF01425.21 KZN93397.1 - 1.5e-55 189.0 0.1 2.7e-48 165.0 0.2 2.1 2 0 0 2 2 2 2 Amidase MFS_1 PF07690.16 KZN93398.1 - 2.2e-31 109.1 30.6 2.2e-31 109.1 30.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KZN93398.1 - 6.2e-05 22.5 8.6 6.2e-05 22.5 8.6 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB NTP_transf_5 PF14907.6 KZN93399.1 - 0.0045 16.7 0.0 0.0063 16.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised nucleotidyltransferase AMP-binding PF00501.28 KZN93400.1 - 1.3e-80 271.1 0.0 2e-80 270.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 KZN93400.1 - 6.8e-73 245.4 0.0 2e-72 243.9 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 KZN93400.1 - 1.7e-62 211.6 0.1 2.7e-62 211.0 0.1 1.2 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 KZN93400.1 - 1.6e-56 191.1 0.0 1.6e-53 181.3 0.0 3.5 3 1 0 4 4 4 1 KR domain PS-DH PF14765.6 KZN93400.1 - 2.5e-47 161.5 0.0 4.3e-47 160.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KZN93400.1 - 1.2e-45 156.4 0.0 2.7e-45 155.3 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 KZN93400.1 - 3.7e-36 124.6 0.0 2e-34 118.9 0.0 2.7 2 1 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.22 KZN93400.1 - 2.9e-33 114.4 0.0 6.6e-33 113.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Epimerase PF01370.21 KZN93400.1 - 9.4e-24 84.2 0.0 1.3e-19 70.7 0.0 2.9 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KZN93400.1 - 5.2e-18 65.2 0.0 1.7e-14 53.7 0.0 3.1 2 1 0 2 2 2 2 short chain dehydrogenase PP-binding PF00550.25 KZN93400.1 - 1.9e-15 57.0 2.2 3.7e-08 33.6 0.2 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KZN93400.1 - 1.8e-13 50.9 0.0 1e-12 48.5 0.0 2.3 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension 3Beta_HSD PF01073.19 KZN93400.1 - 1.8e-09 37.1 0.0 4.5e-07 29.2 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_12 PF08242.12 KZN93400.1 - 8.1e-08 32.9 0.0 2.6e-07 31.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KZN93400.1 - 8.7e-08 32.0 0.0 1.9e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_25 PF13649.6 KZN93400.1 - 1.6e-05 25.5 0.0 5.9e-05 23.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_10 PF13460.6 KZN93400.1 - 1.7e-05 24.8 0.0 0.00065 19.6 0.0 2.8 3 0 0 3 3 3 1 NAD(P)H-binding Thiolase_N PF00108.23 KZN93400.1 - 4.6e-05 22.9 0.1 0.00014 21.3 0.0 1.8 2 0 0 2 2 1 1 Thiolase, N-terminal domain Methyltransf_23 PF13489.6 KZN93400.1 - 0.00026 20.8 0.0 0.00072 19.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN93400.1 - 0.00065 20.3 0.0 0.0019 18.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain AMP-binding_C PF13193.6 KZN93400.1 - 0.0015 19.5 0.0 0.0038 18.2 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 KZN93400.1 - 0.003 17.0 0.0 1 8.7 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KZN93400.1 - 0.018 14.2 0.0 1.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KZN93400.1 - 0.02 14.0 0.0 0.049 12.7 0.0 1.6 1 0 0 1 1 1 0 RmlD substrate binding domain ADH_zinc_N PF00107.26 KZN93401.1 - 7.8e-08 32.4 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KZN93401.1 - 0.00027 20.8 0.5 0.087 12.7 0.0 3.5 3 1 1 4 4 4 2 Alcohol dehydrogenase GroES-like domain DUF1100 PF06500.11 KZN93403.1 - 2.5e-05 23.2 0.0 3.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_6 PF12697.7 KZN93403.1 - 5.2e-05 24.0 0.7 9.1e-05 23.2 0.7 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.16 KZN93404.1 - 1.6e-44 152.3 48.1 1.3e-43 149.3 47.4 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KZN93404.1 - 5.1e-16 58.2 19.5 9.8e-16 57.3 19.6 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KZN93404.1 - 5.2e-15 55.3 14.2 5.2e-15 55.3 14.2 3.5 3 1 1 4 4 4 2 Sugar (and other) transporter SirB PF04247.12 KZN93404.1 - 7.2 6.7 19.6 0.21 11.7 2.0 3.6 3 1 1 4 4 4 0 Invasion gene expression up-regulator, SirB EthD PF07110.11 KZN93405.1 - 4.4e-08 34.2 0.1 6.1e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 EthD domain Pkinase PF00069.25 KZN93406.1 - 1.4e-25 90.2 0.0 8.9e-25 87.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN93406.1 - 3.9e-14 52.6 0.1 3.3e-12 46.3 0.1 2.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KZN93406.1 - 0.00011 21.2 0.0 0.0052 15.6 0.0 2.0 1 1 1 2 2 2 2 Fungal protein kinase FTA2 PF13095.6 KZN93406.1 - 0.0055 16.4 0.0 0.0088 15.7 0.0 1.4 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KZN93406.1 - 0.0056 16.6 0.1 0.31 10.9 0.4 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Glyco_hydro_1 PF00232.18 KZN93408.1 - 2.8e-156 520.5 0.0 3.5e-156 520.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Kelch_4 PF13418.6 KZN93409.1 - 2.8e-26 91.3 10.2 5e-07 29.6 0.0 5.3 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KZN93409.1 - 1.9e-23 82.0 0.4 0.00029 20.7 0.0 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 KZN93409.1 - 8e-21 73.2 0.4 2.3e-05 24.2 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 KZN93409.1 - 2e-20 72.3 1.6 3e-05 24.1 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 KZN93409.1 - 2.6e-20 72.2 7.8 2e-08 34.3 0.1 5.8 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 KZN93409.1 - 3.6e-19 68.1 0.1 1.5e-05 24.5 0.1 4.7 4 0 0 4 4 4 4 Kelch motif BTB PF00651.31 KZN93409.1 - 6e-10 39.3 0.0 1.1e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain ANAPC4_WD40 PF12894.7 KZN93410.1 - 5.1e-15 55.6 5.7 5.2e-06 26.7 0.2 4.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KZN93410.1 - 1.3e-14 54.3 18.9 0.00045 21.0 0.1 6.9 6 1 1 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KZN93410.1 - 1.3e-05 24.4 0.1 0.0014 17.7 0.0 3.2 1 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KZN93410.1 - 0.00014 21.8 0.4 0.012 15.5 0.2 2.6 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A TFIIA PF03153.13 KZN93411.1 - 1.1e-83 282.5 2.3 1.6e-83 282.0 2.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 KZN93411.1 - 2.9 7.6 7.8 3.2 7.4 7.2 1.4 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-C2H2 PF00096.26 KZN93412.1 - 2.3e-05 24.6 10.2 0.071 13.6 1.5 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 KZN93412.1 - 3.5e-05 24.0 0.6 0.024 14.8 0.0 2.2 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 KZN93412.1 - 0.00014 22.4 11.8 0.03 15.1 1.1 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KZN93412.1 - 0.013 15.8 1.0 1.2 9.5 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KZN93412.1 - 0.02 15.3 0.5 0.02 15.3 0.5 3.3 3 0 0 3 3 3 0 Zinc-finger double domain DUF4719 PF15843.5 KZN93412.1 - 0.13 12.4 2.6 0.24 11.5 0.0 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4719) MMM1 PF10296.9 KZN93415.1 - 0.014 14.5 0.0 0.027 13.5 0.0 1.4 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 Bap31 PF05529.12 KZN93415.1 - 0.024 14.5 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 Bap31/Bap29 transmembrane region Bap31 PF05529.12 KZN93416.1 - 3.8e-50 169.3 5.4 4.7e-50 168.9 5.4 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KZN93416.1 - 6.9e-14 51.6 4.7 1.2e-13 50.8 4.7 1.4 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain FlxA PF14282.6 KZN93416.1 - 0.041 13.9 1.6 0.064 13.3 1.6 1.3 1 0 0 1 1 1 0 FlxA-like protein Cluap1 PF10234.9 KZN93416.1 - 0.1 12.0 0.6 0.13 11.6 0.6 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 DivIC PF04977.15 KZN93416.1 - 0.13 12.1 2.2 5.2 6.9 0.1 2.8 3 0 0 3 3 3 0 Septum formation initiator Peptidase_M24 PF00557.24 KZN93417.1 - 4.7e-24 85.2 0.0 5.7e-24 85.0 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 Dus PF01207.17 KZN93418.1 - 8.4e-40 136.8 0.0 9.5e-28 97.2 0.0 2.8 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 KZN93418.1 - 1e-05 25.2 0.7 1e-05 25.2 0.7 3.1 3 0 0 3 3 3 1 CCCH-type zinc finger Torus PF16131.5 KZN93418.1 - 0.00073 20.2 8.5 0.013 16.2 3.2 2.7 1 1 1 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KZN93418.1 - 0.0012 18.8 0.5 0.0012 18.8 0.5 2.8 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH PF00642.24 KZN93418.1 - 0.0018 18.1 2.2 0.0025 17.7 0.4 2.2 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Metallophos PF00149.28 KZN93420.1 - 1.1e-08 35.8 1.5 1.5e-08 35.4 1.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Senescence PF06911.12 KZN93421.1 - 2.7e-54 184.3 4.4 3.7e-54 183.8 4.4 1.2 1 0 0 1 1 1 1 Senescence-associated protein DUF3082 PF11282.8 KZN93421.1 - 0.0059 16.8 0.1 0.012 15.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3082) Pkinase PF00069.25 KZN93422.1 - 4.7e-63 213.0 0.0 7.8e-63 212.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN93422.1 - 1.7e-35 122.6 0.0 5.5e-30 104.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KZN93422.1 - 3.3e-06 26.7 0.0 0.0048 16.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KZN93422.1 - 0.00039 20.4 0.0 0.0013 18.7 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KZN93422.1 - 0.0012 18.5 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KZN93422.1 - 0.021 14.2 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KZN93422.1 - 0.028 13.4 0.1 0.044 12.7 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Ldh_2 PF02615.14 KZN93423.1 - 8e-124 413.1 0.3 9e-124 413.0 0.3 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Fungal_trans PF04082.18 KZN93424.1 - 1.6e-10 40.4 1.1 2.9e-10 39.6 0.0 1.8 2 1 0 2 2 2 1 Fungal specific transcription factor domain adh_short PF00106.25 KZN93425.1 - 2.1e-14 53.4 0.0 5.1e-09 35.9 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KZN93425.1 - 0.0048 16.8 0.0 0.0072 16.3 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KZN93425.1 - 0.017 14.7 0.0 0.056 13.0 0.0 1.8 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.12 KZN93425.1 - 0.019 14.1 0.0 0.045 12.9 0.0 1.6 1 0 0 1 1 1 0 Male sterility protein NAD_binding_10 PF13460.6 KZN93425.1 - 0.1 12.5 0.0 0.48 10.3 0.0 2.0 2 0 0 2 2 2 0 NAD(P)H-binding SIMPL PF04402.14 KZN93427.1 - 1.8e-29 103.7 0.0 2e-29 103.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Fungal_trans PF04082.18 KZN93428.1 - 1.6e-15 56.9 0.5 1.5e-12 47.1 0.1 2.2 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN93428.1 - 1.8e-05 24.7 8.8 3.8e-05 23.7 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AraC_binding_2 PF14525.6 KZN93428.1 - 0.075 12.7 0.8 0.19 11.4 0.1 2.0 3 0 0 3 3 3 0 AraC-binding-like domain Dabb PF07876.12 KZN93429.1 - 2.6e-13 50.4 0.1 4.2e-13 49.7 0.1 1.3 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain FAD_binding_3 PF01494.19 KZN93430.1 - 5.6e-74 249.5 0.0 8.6e-74 248.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KZN93430.1 - 0.0011 18.3 0.0 0.011 14.9 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KZN93430.1 - 0.0016 18.9 0.0 0.069 13.7 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN93430.1 - 0.0041 17.3 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KZN93430.1 - 0.0048 16.2 0.2 0.028 13.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KZN93430.1 - 0.019 14.1 0.1 2.9 6.9 0.0 2.4 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 KZN93430.1 - 0.03 13.7 0.0 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase DAO PF01266.24 KZN93430.1 - 0.067 12.8 0.1 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase MCD_N PF17408.2 KZN93430.1 - 0.11 12.6 0.0 3.8 7.7 0.0 2.5 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain HI0933_like PF03486.14 KZN93430.1 - 0.15 10.7 0.0 0.29 9.8 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein DUF3347 PF11827.8 KZN93430.1 - 0.18 12.0 0.0 0.3 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) MFS_1 PF07690.16 KZN93431.1 - 4.1e-27 95.0 37.7 1.6e-26 93.1 37.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN93431.1 - 1.9e-09 36.9 13.6 1.9e-09 36.9 13.6 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter Acyl-CoA_dh_1 PF00441.24 KZN93433.1 - 9.6e-39 133.0 7.3 1.6e-38 132.3 7.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KZN93433.1 - 7.3e-28 97.5 1.5 1.5e-27 96.5 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KZN93433.1 - 9.4e-25 86.7 0.0 2.4e-24 85.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KZN93433.1 - 3e-16 59.9 4.1 5.2e-16 59.1 4.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KZN93433.1 - 0.023 14.4 0.0 0.053 13.2 0.0 1.6 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal bZIP_1 PF00170.21 KZN93434.1 - 6.4e-06 26.2 6.2 3.3e-05 23.9 5.9 2.1 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KZN93434.1 - 0.0016 18.5 10.7 0.01 15.9 7.4 2.2 1 1 1 2 2 2 1 Basic region leucine zipper Lzipper-MIP1 PF14389.6 KZN93434.1 - 0.0044 17.3 1.3 1.2 9.5 0.1 2.7 1 1 1 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 DUF4618 PF15397.6 KZN93434.1 - 0.0072 15.8 4.2 0.01 15.2 4.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) DUF4200 PF13863.6 KZN93434.1 - 0.015 15.7 2.8 0.024 15.1 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Ribosomal_S20p PF01649.18 KZN93434.1 - 0.052 14.2 3.6 0.076 13.7 3.6 1.2 1 0 0 1 1 1 0 Ribosomal protein S20 Guanylate_kin PF00625.21 KZN93434.1 - 0.087 12.5 1.4 0.13 11.9 1.4 1.2 1 0 0 1 1 1 0 Guanylate kinase LPP PF04728.13 KZN93434.1 - 0.095 13.1 4.6 1.1 9.7 0.7 3.3 3 1 0 3 3 3 0 Lipoprotein leucine-zipper DivIC PF04977.15 KZN93434.1 - 0.12 12.1 3.3 1.4 8.7 0.3 2.3 1 1 1 2 2 2 0 Septum formation initiator Not3 PF04065.15 KZN93434.1 - 0.15 11.5 3.8 0.087 12.2 2.1 1.5 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component ABC_tran_CTD PF16326.5 KZN93434.1 - 0.22 11.8 1.7 0.39 11.0 1.7 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain FlxA PF14282.6 KZN93434.1 - 0.22 11.5 6.2 0.34 10.9 5.0 1.8 1 1 1 2 2 2 0 FlxA-like protein MbeD_MobD PF04899.12 KZN93434.1 - 0.23 11.6 3.0 3.9 7.7 0.1 2.5 1 1 1 2 2 2 0 MbeD/MobD like Spc7 PF08317.11 KZN93434.1 - 0.24 10.2 5.1 0.34 9.8 5.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DEAD PF00270.29 KZN93435.1 - 4.5e-39 134.0 0.0 6.8e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KZN93435.1 - 1.2e-22 80.4 0.0 1.1e-21 77.2 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KZN93435.1 - 6.3e-05 22.3 0.0 9.2e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KZN93435.1 - 0.0004 20.4 0.0 0.00066 19.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KZN93435.1 - 0.0015 18.9 0.0 0.0028 18.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KZN93435.1 - 0.053 13.0 0.0 0.074 12.5 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 KZN93435.1 - 0.16 11.8 0.0 0.39 10.5 0.0 1.6 2 0 0 2 2 2 0 Helicase GWT1 PF06423.12 KZN93436.1 - 4.4e-40 137.2 4.2 1.1e-39 135.9 2.4 2.3 2 1 0 2 2 2 1 GWT1 DUF4818 PF16089.5 KZN93436.1 - 0.097 13.1 0.0 0.097 13.1 0.0 2.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4818) Amidase PF01425.21 KZN93437.1 - 1.7e-84 284.4 0.0 4.3e-84 283.1 0.0 1.5 1 1 0 1 1 1 1 Amidase Pkinase PF00069.25 KZN93438.1 - 4.3e-08 32.8 0.0 9.9e-07 28.4 0.0 2.2 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN93438.1 - 3.3e-05 23.3 0.0 7.8e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KZN93438.1 - 0.0057 16.6 0.0 0.012 15.6 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KZN93438.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PDEase_II PF02112.15 KZN93439.1 - 4.5e-54 183.8 0.0 2.4e-26 92.6 0.0 3.0 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B PF00753.27 KZN93439.1 - 0.00084 19.4 0.1 0.0019 18.3 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KZN93439.1 - 0.0018 17.8 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain SPRY PF00622.28 KZN93440.1 - 2.5e-19 69.5 0.0 4.2e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Peptidase_M24 PF00557.24 KZN93441.1 - 1.6e-58 197.8 0.0 2.3e-58 197.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KZN93441.1 - 4.7e-23 81.2 0.0 9.2e-23 80.3 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain HIG_1_N PF04588.13 KZN93442.1 - 1.3e-05 25.3 0.4 1.3e-05 25.3 0.4 1.7 2 0 0 2 2 2 1 Hypoxia induced protein conserved region Iso_dh PF00180.20 KZN93443.1 - 1.7e-129 431.9 0.0 1.9e-129 431.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ANAPC10 PF03256.16 KZN93444.1 - 1.2e-42 145.6 0.0 1.8e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) TPP_enzyme_N PF02776.18 KZN93446.1 - 1.8e-27 96.1 0.0 3e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KZN93446.1 - 2.6e-15 56.5 0.0 6e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KZN93446.1 - 3.5e-13 49.5 0.0 6.4e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain adh_short_C2 PF13561.6 KZN93447.1 - 1.3e-58 198.3 2.8 1.5e-58 198.1 2.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN93447.1 - 1.1e-41 142.5 2.7 1.3e-41 142.2 2.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN93447.1 - 3e-14 53.3 1.2 4e-14 52.9 1.2 1.1 1 0 0 1 1 1 1 KR domain NAD_Gly3P_dh_N PF01210.23 KZN93447.1 - 0.013 15.5 0.8 0.032 14.2 0.9 1.7 1 1 1 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 KZN93447.1 - 0.045 13.6 1.1 0.086 12.7 1.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 KZN93447.1 - 0.078 12.4 0.7 0.52 9.7 0.7 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pkinase PF00069.25 KZN93448.1 - 2.2e-53 181.3 0.0 1.4e-50 172.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KZN93448.1 - 9.3e-33 113.6 0.0 3.4e-32 111.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KZN93448.1 - 0.00054 19.4 0.0 0.00081 18.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KZN93448.1 - 0.0025 16.7 0.0 0.0039 16.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 KZN93448.1 - 0.0026 16.8 0.1 0.0043 16.1 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 KZN93448.1 - 0.056 12.4 0.0 0.079 11.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Meth_synt_2 PF01717.18 KZN93449.1 - 1.6e-09 37.5 0.0 2.7e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 Cobalamin-independent synthase, Catalytic domain Oberon_cc PF16312.5 KZN93449.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 Coiled-coil region of Oberon Pyr_redox_2 PF07992.14 KZN93450.1 - 5.5e-54 183.4 0.7 9e-54 182.7 0.7 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KZN93450.1 - 1.1e-31 109.3 0.1 2.3e-31 108.3 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KZN93450.1 - 1.9e-13 50.8 0.2 1.9e-13 50.8 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KZN93450.1 - 5.7e-09 35.6 0.1 7e-08 32.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KZN93450.1 - 0.00046 19.4 0.0 0.00084 18.6 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 KZN93450.1 - 0.088 12.7 0.2 0.23 11.4 0.2 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 KZN93450.1 - 0.11 11.9 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KZN93450.1 - 1.4 7.9 6.8 13 4.7 1.0 2.9 3 0 0 3 3 3 0 FAD binding domain Amidohydro_2 PF04909.14 KZN93452.1 - 9.5e-25 88.0 0.0 1.1e-24 87.8 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Sugar_tr PF00083.24 KZN93453.1 - 1.4e-80 271.4 14.7 1.6e-80 271.2 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN93453.1 - 6.8e-16 58.1 18.8 6.8e-16 58.1 18.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Dynein_AAA_lid PF17852.1 KZN93453.1 - 0.089 12.9 0.3 0.9 9.6 0.0 2.6 3 0 0 3 3 3 0 Dynein heavy chain AAA lid domain Fungal_trans PF04082.18 KZN93454.1 - 3.8e-23 81.9 0.2 6.3e-23 81.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN93454.1 - 2.1e-10 40.5 8.5 3.6e-10 39.8 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.29 KZN93455.1 - 3.4e-46 157.2 0.0 7e-46 156.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KZN93455.1 - 4.9e-31 107.4 0.3 4.4e-29 101.0 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UTP25 PF06862.12 KZN93455.1 - 3.7e-05 22.7 1.3 0.0003 19.7 0.2 2.7 2 1 1 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Spem1 PF15670.5 KZN93455.1 - 2.6 7.6 6.7 0.45 10.1 2.6 1.8 2 0 0 2 2 2 0 Spermatid maturation protein 1 Acetyltransf_4 PF13420.7 KZN93456.1 - 4.7e-07 30.1 0.0 2.8e-06 27.5 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Arf PF00025.21 KZN93457.1 - 2.7e-59 199.5 1.2 3.2e-59 199.3 1.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KZN93457.1 - 2.9e-09 36.6 1.7 0.00049 19.4 0.4 2.6 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KZN93457.1 - 1.9e-08 34.1 0.0 2.2e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KZN93457.1 - 3.2e-08 33.8 0.1 4.5e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KZN93457.1 - 4.1e-08 32.9 0.0 5e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KZN93457.1 - 7.6e-06 26.0 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KZN93457.1 - 8.3e-06 25.4 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KZN93457.1 - 2.6e-05 23.9 0.1 0.0011 18.6 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain NACHT PF05729.12 KZN93457.1 - 0.0086 16.0 1.0 0.037 14.0 1.0 1.8 1 1 0 1 1 1 1 NACHT domain cobW PF02492.19 KZN93457.1 - 0.011 15.4 0.1 0.29 10.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain HCV_NS1 PF01560.17 KZN93457.1 - 0.011 14.4 0.1 0.014 14.1 0.1 1.2 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein E2/NS1 AAA_22 PF13401.6 KZN93457.1 - 0.039 14.2 0.0 0.057 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 KZN93457.1 - 0.19 11.0 0.2 0.45 9.8 0.1 1.6 2 0 0 2 2 2 0 6-phosphofructo-2-kinase DUF4045 PF13254.6 KZN93458.1 - 1.6e-111 373.9 68.3 4e-68 231.0 36.3 6.7 3 3 3 7 7 7 2 Domain of unknown function (DUF4045) Gelsolin PF00626.22 KZN93458.1 - 2.4e-09 37.0 0.0 0.0014 18.5 0.0 3.6 3 0 0 3 3 3 3 Gelsolin repeat ALO PF04030.14 KZN93459.1 - 1.6e-87 293.6 0.1 2.3e-87 293.1 0.1 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KZN93459.1 - 1.1e-30 106.2 0.1 1.8e-30 105.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Arginase PF00491.21 KZN93460.1 - 1.7e-86 290.2 0.0 2.2e-86 289.8 0.0 1.0 1 0 0 1 1 1 1 Arginase family Fungal_trans_2 PF11951.8 KZN93461.1 - 9.4e-08 31.3 1.5 2.5e-07 29.8 0.1 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN93461.1 - 5.3e-07 29.7 8.5 9.3e-07 28.9 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.13 KZN93462.1 - 1.6e-70 237.0 10.2 1.6e-70 237.0 10.2 1.4 2 0 0 2 2 2 1 RTA1 like protein Ank_2 PF12796.7 KZN93463.1 - 2.5e-47 159.4 0.0 4.8e-14 52.7 0.2 4.5 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 KZN93463.1 - 1.3e-36 123.5 8.3 0.00016 22.0 0.0 8.3 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 KZN93463.1 - 1.3e-34 118.1 13.3 9.9e-13 48.3 0.1 6.7 5 2 1 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN93463.1 - 7.8e-33 108.8 6.5 0.00016 21.8 0.0 8.8 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 KZN93463.1 - 1.6e-32 111.1 8.5 1.5e-07 31.5 0.2 6.7 2 2 4 6 6 6 6 Ankyrin repeats (many copies) CorA PF01544.18 KZN93463.1 - 1.6e-13 50.6 0.9 3.2e-13 49.6 0.9 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF569 PF04601.13 KZN93463.1 - 0.41 10.3 1.5 0.6 9.8 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF569) S6PP_C PF08472.10 KZN93464.1 - 0.021 14.7 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal Aminotran_1_2 PF00155.21 KZN93465.1 - 1e-18 67.7 0.0 1.4e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KZN93465.1 - 0.0023 16.8 0.0 0.28 9.9 0.0 2.1 2 0 0 2 2 2 2 Alanine-glyoxylate amino-transferase Pectate_lyase_3 PF12708.7 KZN93466.1 - 2.5e-101 338.0 16.8 3.6e-88 295.0 7.3 2.8 2 1 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KZN93466.1 - 1.8e-07 30.8 0.9 0.0059 16.3 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase NosD PF05048.13 KZN93466.1 - 0.0038 16.5 0.6 0.0097 15.2 0.6 1.7 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Cation_efflux PF01545.21 KZN93467.1 - 1.7e-15 57.3 7.8 2.2e-15 56.9 7.8 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KZN93467.1 - 1.1e-10 41.4 0.1 3.3e-10 39.9 0.1 1.8 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Adaptin_binding PF10199.9 KZN93467.1 - 2.3 8.9 4.7 9.8 6.8 4.7 1.9 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Pro_isomerase PF00160.21 KZN93469.1 - 7.5e-45 153.0 0.4 8.7e-45 152.8 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.6 KZN93469.1 - 0.14 12.2 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Methyltransf_25 PF13649.6 KZN93470.1 - 4.1e-13 49.8 0.0 8.6e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN93470.1 - 3.8e-12 46.7 0.0 7.6e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN93470.1 - 2.3e-11 43.7 0.0 3.2e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN93470.1 - 4.4e-09 37.0 0.0 8.9e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN93470.1 - 3.2e-07 30.3 0.0 4.8e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KZN93470.1 - 8.1e-05 22.2 0.0 0.00017 21.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KZN93470.1 - 0.004 16.5 0.0 0.0063 15.8 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain TehB PF03848.14 KZN93470.1 - 0.0093 15.4 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 KZN93470.1 - 0.014 15.4 0.0 0.022 14.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 KZN93470.1 - 0.039 13.4 0.0 2.2 7.7 0.0 2.1 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.17 KZN93470.1 - 0.068 12.6 0.0 0.099 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.18 KZN93470.1 - 0.069 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_5 PF01795.19 KZN93470.1 - 0.1 12.1 0.0 0.33 10.4 0.0 1.8 3 0 0 3 3 3 0 MraW methylase family LPMO_10 PF03067.15 KZN93471.1 - 6.6e-15 56.3 0.8 1.1e-14 55.6 0.8 1.4 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Pollen_Ole_e_I PF01190.17 KZN93471.1 - 0.025 15.0 0.3 2.4 8.6 0.1 2.3 2 0 0 2 2 2 0 Pollen proteins Ole e I like ADH_zinc_N_2 PF13602.6 KZN93472.1 - 3.2e-23 83.3 0.0 5e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KZN93472.1 - 1.2e-17 64.1 0.1 1.7e-17 63.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KZN93472.1 - 0.059 12.8 0.1 5.8 6.3 0.2 2.1 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Methyltransf_23 PF13489.6 KZN93473.1 - 3e-11 43.4 0.0 4.5e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN93473.1 - 1.1e-05 26.0 0.0 3e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN93473.1 - 0.0057 17.4 0.0 0.022 15.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KZN93473.1 - 0.015 14.6 0.0 0.044 13.1 0.0 1.6 1 1 0 1 1 1 0 O-methyltransferase domain MTS PF05175.14 KZN93473.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 KZN93473.1 - 0.097 13.3 0.0 0.36 11.5 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 KZN93473.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase GAT PF03127.14 KZN93474.1 - 1.3e-16 60.7 0.1 3.1e-16 59.4 0.1 1.7 1 0 0 1 1 1 1 GAT domain VHS PF00790.19 KZN93474.1 - 0.0003 20.7 0.0 0.00061 19.7 0.0 1.5 1 0 0 1 1 1 1 VHS domain DUF4656 PF15551.6 KZN93474.1 - 0.0072 15.9 0.7 0.013 15.1 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4656) HAD_2 PF13419.6 KZN93475.1 - 2.5e-10 40.7 0.0 1.3e-09 38.4 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KZN93475.1 - 0.0068 16.7 0.0 0.36 11.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase EcoEI_R_C PF08463.10 KZN93475.1 - 0.029 14.5 0.0 0.044 13.9 0.0 1.2 1 0 0 1 1 1 0 EcoEI R protein C-terminal NAS PF03059.16 KZN93475.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Nicotianamine synthase protein 2-Hacid_dh_C PF02826.19 KZN93476.1 - 1.1e-53 181.2 0.0 1.9e-53 180.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ribosomal_L22 PF00237.19 KZN93476.1 - 5.5e-39 132.5 0.0 2.1e-38 130.7 0.0 2.0 1 1 1 2 2 2 1 Ribosomal protein L22p/L17e 2-Hacid_dh PF00389.30 KZN93476.1 - 1.3e-18 67.0 0.0 2.9e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KZN93476.1 - 0.0042 17.3 0.5 0.01 16.0 0.2 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_N PF08240.12 KZN93477.1 - 1.3e-28 99.1 0.8 2.3e-28 98.2 0.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KZN93477.1 - 6.8e-14 51.9 0.3 2.1e-06 27.4 0.0 2.3 1 1 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N PF00107.26 KZN93477.1 - 4.9e-13 49.2 0.3 1.6e-12 47.5 0.3 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 KZN93477.1 - 1.5e-05 25.3 0.1 2.8e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 KZN93477.1 - 0.025 14.2 0.0 0.051 13.2 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ADH_zinc_N_2 PF13602.6 KZN93477.1 - 0.066 14.3 0.0 0.14 13.2 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 KZN93478.1 - 1.8e-45 155.3 0.7 2.2e-45 155.0 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN93478.1 - 4.3e-43 147.1 0.3 5.8e-43 146.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN93478.1 - 3.6e-12 46.5 0.4 5.1e-12 46.1 0.4 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KZN93478.1 - 1.3e-05 25.2 0.1 2.8e-05 24.1 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KZN93478.1 - 8.5e-05 22.1 0.2 0.00015 21.3 0.2 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KZN93478.1 - 0.00011 21.8 0.2 0.00024 20.7 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KZN93478.1 - 0.00058 19.1 0.0 0.00076 18.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KZN93478.1 - 0.0042 17.3 0.1 0.0066 16.7 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ACT_7 PF13840.6 KZN93478.1 - 0.13 12.1 0.1 0.64 9.8 0.0 2.1 2 0 0 2 2 2 0 ACT domain Fungal_trans PF04082.18 KZN93479.1 - 4e-11 42.5 0.0 6.3e-10 38.5 0.0 2.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN93479.1 - 3.4e-05 23.9 10.8 5.9e-05 23.1 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 KZN93480.1 - 2.2e-52 177.9 0.1 2.8e-52 177.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN93480.1 - 1.6e-49 168.1 0.0 2.1e-49 167.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN93480.1 - 8.5e-10 38.8 0.1 2.1e-09 37.5 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KZN93480.1 - 4.3e-05 23.1 0.0 5.4e-05 22.8 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KZN93480.1 - 0.0049 16.2 0.1 0.017 14.4 0.0 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.17 KZN93480.1 - 0.0092 15.1 0.1 0.037 13.1 0.0 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KZN93480.1 - 0.017 14.5 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_7 PF13241.6 KZN93480.1 - 0.12 12.8 0.1 0.35 11.3 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Ferric_reduct PF01794.19 KZN93481.1 - 9.5e-26 90.4 7.4 2.6e-25 88.9 7.4 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KZN93481.1 - 3.6e-12 46.7 0.0 1.4e-07 31.7 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KZN93481.1 - 1.1e-10 41.6 0.4 3.5e-06 27.1 0.1 2.7 3 0 0 3 3 3 2 FAD-binding domain NAD_binding_1 PF00175.21 KZN93481.1 - 0.022 15.4 0.0 0.29 11.8 0.0 2.7 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain ABC2_membrane PF01061.24 KZN93482.1 - 1.2e-85 286.2 62.5 1.7e-48 164.9 21.5 3.4 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KZN93482.1 - 4.2e-39 134.2 0.2 2.1e-18 67.1 0.0 3.3 4 0 0 4 4 3 2 ABC transporter PDR_CDR PF06422.12 KZN93482.1 - 8.3e-37 125.0 1.6 3.5e-33 113.4 0.1 3.5 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KZN93482.1 - 3.4e-19 69.2 0.2 8.9e-19 67.9 0.2 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 KZN93482.1 - 5.1e-07 29.7 0.5 6.9e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KZN93482.1 - 2.3e-05 24.8 0.1 0.0047 17.3 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KZN93482.1 - 9.9e-05 22.0 0.0 0.00057 19.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KZN93482.1 - 0.00069 19.3 1.4 0.028 14.1 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KZN93482.1 - 0.0017 18.3 0.0 2.9 7.6 0.1 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KZN93482.1 - 0.0019 18.7 0.0 0.026 15.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KZN93482.1 - 0.002 18.3 1.5 0.026 14.7 0.1 2.9 3 0 0 3 3 3 1 AAA domain ABC2_membrane_3 PF12698.7 KZN93482.1 - 0.003 16.7 16.6 0.003 16.7 16.6 2.9 2 1 0 2 2 2 1 ABC-2 family transporter protein SMC_N PF02463.19 KZN93482.1 - 0.0054 16.2 0.0 0.45 9.9 0.0 3.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.6 KZN93482.1 - 0.03 14.8 0.2 1.6 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KZN93482.1 - 0.037 14.3 1.0 1.2 9.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KZN93482.1 - 0.054 13.2 0.7 3.5 7.3 0.2 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KZN93482.1 - 0.056 13.4 3.7 3.8 7.4 0.2 3.2 3 0 0 3 3 3 0 NACHT domain IstB_IS21 PF01695.17 KZN93482.1 - 0.056 13.2 0.3 2.4 7.9 0.0 2.6 3 0 0 3 3 2 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KZN93482.1 - 0.074 13.4 0.0 23 5.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 KZN93482.1 - 0.13 12.7 0.1 31 5.0 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KZN93482.1 - 0.31 10.6 0.7 1.2 8.6 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain UBA_4 PF14555.6 KZN93484.1 - 1.6e-10 40.6 0.0 3.5e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KZN93484.1 - 3.4e-09 36.8 0.0 8.6e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 UBX domain Atg14 PF10186.9 KZN93484.1 - 0.31 10.1 3.3 0.51 9.4 3.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1682 PF07946.14 KZN93484.1 - 0.91 8.7 5.9 1.8 7.7 5.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DDRGK PF09756.9 KZN93484.1 - 9.1 5.8 11.5 15 5.1 11.5 1.3 1 0 0 1 1 1 0 DDRGK domain Whirly PF08536.11 KZN93485.1 - 0.072 12.9 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 Whirly transcription factor zf-CCCH PF00642.24 KZN93485.1 - 0.19 11.7 1.6 0.39 10.7 1.6 1.5 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pan3_PK PF18101.1 KZN93486.1 - 2e-62 209.2 0.0 3.1e-62 208.6 0.0 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KZN93486.1 - 2.2e-06 27.2 0.0 3.6e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN93486.1 - 0.042 13.1 0.0 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Fasciclin PF02469.22 KZN93487.1 - 9.9e-42 142.2 0.0 4.7e-23 81.8 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain Dioxygenase_C PF00775.21 KZN93488.1 - 1.3e-39 135.5 0.0 1.9e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KZN93488.1 - 1.4e-32 111.3 0.0 2.5e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Zn_clus PF00172.18 KZN93489.1 - 0.06 13.5 9.9 0.14 12.3 9.9 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain LSM PF01423.22 KZN93490.1 - 7e-22 76.9 0.4 8.6e-22 76.6 0.4 1.1 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.6 KZN93490.1 - 0.0011 19.4 5.8 0.0019 18.7 5.8 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 DUF150_C PF17384.2 KZN93490.1 - 0.0039 17.3 0.1 0.0061 16.7 0.1 1.3 1 0 0 1 1 1 1 RimP C-terminal SH3 domain SM-ATX PF14438.6 KZN93490.1 - 0.087 13.0 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Vps39_2 PF10367.9 KZN93491.1 - 2.8e-06 27.7 0.0 9.9e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 KZN93491.1 - 0.0056 16.9 0.0 0.017 15.4 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 CASP_C PF08172.12 KZN93492.1 - 1.3e-89 299.9 2.4 1.3e-89 299.9 2.4 3.3 2 1 2 4 4 4 1 CASP C terminal ZapB PF06005.12 KZN93492.1 - 0.062 13.8 0.4 0.062 13.8 0.4 6.8 6 1 0 6 6 6 0 Cell division protein ZapB ALMT PF11744.8 KZN93492.1 - 1.8 7.3 12.0 1.5 7.6 0.2 2.7 2 0 0 2 2 2 0 Aluminium activated malate transporter SlyX PF04102.12 KZN93492.1 - 2.6 8.7 0.0 2.6 8.7 0.0 5.9 6 0 0 6 6 6 0 SlyX Fib_alpha PF08702.10 KZN93492.1 - 8.5 6.6 25.3 29 4.8 0.1 4.3 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family DUF3455 PF11937.8 KZN93493.1 - 7.3e-47 159.7 0.1 9.6e-47 159.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 KZN93493.1 - 1.3e-31 108.5 0.2 2.7e-31 107.5 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2990) Fibrillarin PF01269.17 KZN93494.1 - 6.4e-104 346.0 0.0 7.8e-104 345.7 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KZN93494.1 - 3.9e-06 26.7 0.0 6.7e-06 26.0 0.0 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KZN93494.1 - 0.013 15.2 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Epimerase PF01370.21 KZN93495.1 - 5.2e-20 71.9 0.0 6.8e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KZN93495.1 - 2e-12 46.7 0.0 2.6e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KZN93495.1 - 4e-12 46.2 0.0 8.9e-12 45.0 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KZN93495.1 - 1.4e-06 27.6 0.0 2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KZN93495.1 - 0.00067 19.6 0.0 0.00096 19.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KZN93495.1 - 0.0013 18.0 0.0 0.13 11.4 0.0 2.5 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KZN93495.1 - 0.0017 17.5 0.0 0.0034 16.5 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KZN93495.1 - 0.0036 17.5 0.0 0.0059 16.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 KZN93495.1 - 0.0042 16.6 0.0 0.011 15.3 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase Ldh_1_N PF00056.23 KZN93495.1 - 0.0076 16.3 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain KR PF08659.10 KZN93495.1 - 0.0086 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 KZN93495.1 - 0.02 15.3 0.0 0.038 14.4 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Peptidase_M16 PF00675.20 KZN93496.1 - 4.2e-56 189.1 0.7 9.4e-56 187.9 0.2 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KZN93496.1 - 2.3e-41 141.8 0.0 4.5e-39 134.3 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain MTD PF01993.18 KZN93496.1 - 0.061 12.7 0.0 6.5 6.0 0.0 2.3 1 1 1 2 2 2 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase Methyltr_RsmB-F PF01189.17 KZN93498.1 - 1.9e-32 112.6 0.0 4.6e-25 88.4 0.0 3.3 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F ROKNT PF08067.11 KZN93498.1 - 3.4 8.0 7.3 25 5.3 0.1 2.6 2 0 0 2 2 2 0 ROKNT (NUC014) domain Glyco_hydro_35 PF01301.19 KZN93499.1 - 2.4e-99 332.9 0.0 8.7e-99 331.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 KZN93499.1 - 1.4e-60 204.2 2.6 2.7e-60 203.3 2.6 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 KZN93499.1 - 4.2e-55 185.2 5.1 7.1e-32 110.4 0.1 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 KZN93499.1 - 7.5e-23 79.9 0.1 1.7e-22 78.8 0.1 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Glyco_transf_54 PF04666.13 KZN93502.1 - 2.2e-11 43.1 0.0 2.9e-10 39.5 0.0 2.3 2 1 0 2 2 2 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region CYSTM PF12734.7 KZN93503.1 - 7.1e-12 45.4 8.2 7.1e-12 45.4 8.2 4.8 3 2 1 4 4 4 1 Cysteine-rich TM module stress tolerance RNA_pol_Rpb5_C PF01191.19 KZN93504.1 - 5.9e-34 115.8 0.1 9.6e-34 115.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KZN93504.1 - 1.6e-23 83.1 0.0 2.4e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 KZN93504.1 - 0.015 15.3 0.0 0.036 14.1 0.0 1.6 2 0 0 2 2 2 0 Restriction endonuclease EzrA PF06160.12 KZN93505.1 - 0.00014 20.2 13.1 0.00014 20.2 13.1 3.6 2 1 0 3 3 3 3 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.9 KZN93505.1 - 0.0093 16.0 4.5 0.0093 16.0 4.5 4.8 3 1 2 5 5 5 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ABC_tran_CTD PF16326.5 KZN93505.1 - 0.03 14.5 3.1 0.03 14.5 3.1 6.9 3 2 4 7 7 7 0 ABC transporter C-terminal domain Osmo_CC PF08946.10 KZN93505.1 - 0.22 11.8 16.1 0.89 9.9 1.3 5.1 4 1 0 4 4 4 0 Osmosensory transporter coiled coil Fib_alpha PF08702.10 KZN93505.1 - 0.45 10.7 30.3 0.061 13.5 4.0 5.0 2 1 4 6 6 6 0 Fibrinogen alpha/beta chain family Zw10 PF06248.13 KZN93505.1 - 0.48 8.9 16.4 0.013 14.1 8.1 2.3 2 1 1 3 3 3 0 Centromere/kinetochore Zw10 Aminotran_1_2 PF00155.21 KZN93507.1 - 5.1e-63 213.4 0.0 6e-63 213.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 KZN93507.1 - 0.042 12.7 0.0 0.062 12.2 0.0 1.2 1 0 0 1 1 1 0 Allinase Zn_clus PF00172.18 KZN93508.1 - 2.2e-10 40.5 16.7 4.6e-10 39.5 16.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN93508.1 - 4.3e-08 32.5 0.0 1.1e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane PF01061.24 KZN93509.1 - 6e-82 274.1 56.0 3e-42 144.4 19.2 2.9 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 KZN93509.1 - 1.1e-36 124.6 0.3 2.2e-34 117.2 0.0 3.5 4 0 0 4 4 2 2 CDR ABC transporter ABC_tran PF00005.27 KZN93509.1 - 9.4e-33 113.6 0.0 3.2e-15 56.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 KZN93509.1 - 5.9e-12 46.0 0.0 1.6e-11 44.7 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 KZN93509.1 - 4.4e-07 30.0 0.2 3.4e-05 23.8 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase ABC2_membrane_3 PF12698.7 KZN93509.1 - 5.7e-06 25.7 39.4 0.0016 17.7 14.4 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_18 PF13238.6 KZN93509.1 - 2.7e-05 24.7 0.0 0.011 16.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KZN93509.1 - 3.1e-05 23.6 0.2 0.00032 20.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KZN93509.1 - 0.00013 22.4 0.1 0.014 15.8 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KZN93509.1 - 0.00042 20.0 0.5 0.048 13.4 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KZN93509.1 - 0.0005 20.0 0.0 2.2 8.0 0.0 3.6 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 KZN93509.1 - 0.0006 20.0 0.1 0.037 14.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KZN93509.1 - 0.00085 18.8 0.0 0.14 11.6 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.6 KZN93509.1 - 0.0093 16.4 0.6 2.8 8.4 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KZN93509.1 - 0.01 16.3 0.5 1.3 9.4 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KZN93509.1 - 0.037 14.3 0.7 2.3 8.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KZN93509.1 - 0.041 14.1 0.3 3.9 7.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KZN93509.1 - 0.043 13.4 0.7 1.8 8.1 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KZN93509.1 - 0.12 12.0 0.6 4.5 6.9 0.5 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KZN93509.1 - 0.14 12.3 0.0 24 5.0 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 KZN93509.1 - 0.16 11.9 4.4 4 7.3 0.4 2.9 3 0 0 3 3 3 0 NACHT domain DUF1115 PF06544.12 KZN93510.1 - 4.7e-11 43.0 0.0 7.6e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Tam41_Mmp37 PF09139.11 KZN93511.1 - 5e-129 430.4 0.0 6.1e-129 430.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial BIR PF00653.21 KZN93512.1 - 9.6e-48 160.7 5.8 6.1e-23 81.3 0.1 2.8 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C2H2_jaz PF12171.8 KZN93513.1 - 7.6e-09 35.6 0.6 1.2e-08 35.0 0.6 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KZN93513.1 - 3.2e-06 27.3 0.7 5.2e-06 26.7 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KZN93513.1 - 0.0015 18.8 0.6 0.0027 18.1 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KZN93513.1 - 0.061 13.7 0.4 0.19 12.1 0.1 1.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KZN93513.1 - 0.24 12.3 0.2 0.24 12.3 0.2 1.7 2 0 0 2 2 2 0 C2H2-type zinc finger DUF3340 PF11818.8 KZN93513.1 - 0.24 11.5 18.5 0.16 12.2 9.9 2.1 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) Atg14 PF10186.9 KZN93513.1 - 6.4 5.8 10.0 9.4 5.2 10.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 F-box-like PF12937.7 KZN93514.1 - 0.00063 19.6 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN93514.1 - 0.0041 17.0 0.0 0.0087 15.9 0.0 1.5 1 0 0 1 1 1 1 F-box domain Pyrid_ox_like PF16242.5 KZN93515.1 - 6e-20 71.3 0.0 9.4e-20 70.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 KZN93515.1 - 4.8e-07 29.9 0.0 7.8e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FMN_bind_2 PF04299.12 KZN93515.1 - 0.096 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative FMN-binding domain TFIID-18kDa PF02269.16 KZN93516.1 - 3.9e-27 94.1 0.1 3.5e-26 91.0 0.0 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit TAFII28 PF04719.14 KZN93516.1 - 0.038 14.1 0.0 0.096 12.8 0.0 1.8 2 0 0 2 2 2 0 hTAFII28-like protein conserved region TP_methylase PF00590.20 KZN93517.1 - 3.8e-24 85.8 0.3 6.3e-24 85.1 0.3 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases MFS_1 PF07690.16 KZN93518.1 - 1.6e-14 53.6 13.7 1.6e-14 53.6 13.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily GDH_N PF12466.8 KZN93519.1 - 0.097 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal APH PF01636.23 KZN93520.1 - 2e-10 41.0 0.0 4e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN93520.1 - 0.00082 19.0 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KZN93520.1 - 0.0035 16.7 0.0 0.0085 15.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain CRAL_TRIO PF00650.20 KZN93520.1 - 0.098 12.4 0.0 0.31 10.8 0.0 1.8 1 1 0 1 1 1 0 CRAL/TRIO domain Arylsulfotran_2 PF14269.6 KZN93521.1 - 3.9e-56 190.6 6.0 5.7e-56 190.1 6.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KZN93521.1 - 1.9e-19 69.8 5.8 2.3e-17 63.0 5.8 2.7 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Sulfotransfer_4 PF17784.1 KZN93522.1 - 5.1e-74 248.7 0.0 6.2e-74 248.5 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KZN93522.1 - 0.00044 20.7 0.1 0.0034 17.8 0.0 2.1 1 1 1 2 2 2 1 Sulfotransferase family Clat_adaptor_s PF01217.20 KZN93523.1 - 9.1e-56 187.7 2.0 1.1e-55 187.5 2.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain P2 PF07194.11 KZN93524.1 - 0.039 14.0 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 P2 response regulator binding domain DUF4114 PF13448.6 KZN93524.1 - 0.075 13.8 0.0 0.13 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4114) Ist1 PF03398.14 KZN93525.1 - 4.3e-43 147.1 2.0 7.8e-22 77.9 3.5 2.3 2 0 0 2 2 2 2 Regulator of Vps4 activity in the MVB pathway MSA-2c PF12238.8 KZN93525.1 - 0.0036 17.4 3.2 0.0053 16.8 0.0 2.1 2 0 0 2 2 2 1 Merozoite surface antigen 2c DUF1289 PF06945.13 KZN93526.1 - 0.0027 17.5 0.4 0.0045 16.7 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) Cys_Met_Meta_PP PF01053.20 KZN93527.1 - 2.4e-62 210.7 0.0 7.6e-62 209.0 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KZN93527.1 - 0.007 15.6 0.0 0.014 14.6 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KZN93527.1 - 0.038 12.9 0.0 0.071 12.0 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V Fungal_trans_2 PF11951.8 KZN93528.1 - 1.6e-41 142.4 1.9 2.1e-41 142.0 1.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN93528.1 - 7.1e-07 29.2 8.7 1.5e-06 28.2 8.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pam17 PF08566.10 KZN93529.1 - 0.073 12.9 0.0 0.08 12.8 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 SUN PF03856.13 KZN93530.1 - 1.1e-82 277.2 5.6 1.6e-82 276.7 5.6 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) SOG2 PF10428.9 KZN93530.1 - 4.3 6.4 32.8 6.5 5.8 32.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Cutinase PF01083.22 KZN93531.1 - 5e-48 163.4 9.8 7.2e-48 162.9 9.8 1.2 1 0 0 1 1 1 1 Cutinase LCM PF04072.14 KZN93531.1 - 2.9e-19 69.7 0.0 4.1e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase PE-PPE PF08237.11 KZN93531.1 - 6.6e-05 22.6 0.4 0.00012 21.7 0.4 1.4 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 KZN93531.1 - 0.092 12.6 0.1 0.22 11.4 0.0 1.6 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) zf-RING_2 PF13639.6 KZN93532.1 - 1.1e-07 32.1 9.0 2.1e-07 31.2 9.0 1.5 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KZN93532.1 - 5.9e-05 23.2 6.2 0.00014 21.9 6.2 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KZN93532.1 - 0.00014 21.9 2.2 0.00035 20.6 2.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KZN93532.1 - 0.0002 21.6 8.0 0.00045 20.4 8.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KZN93532.1 - 0.00041 20.2 9.6 0.00081 19.2 9.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KZN93532.1 - 0.0048 16.7 8.4 0.01 15.6 8.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 KZN93532.1 - 0.17 12.0 7.6 0.41 10.8 7.6 1.7 1 0 0 1 1 1 0 RING-variant domain zf-RING_11 PF17123.5 KZN93532.1 - 0.26 11.1 2.9 0.6 9.9 2.9 1.7 1 0 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 KZN93532.1 - 0.29 10.8 6.2 0.59 9.8 6.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 KZN93532.1 - 0.61 10.4 8.2 1.2 9.5 8.2 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.6 KZN93532.1 - 1.1 9.2 5.7 2.2 8.2 5.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_9 PF13901.6 KZN93532.1 - 1.2 9.0 6.8 13 5.7 7.3 2.2 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon C1_1 PF00130.22 KZN93532.1 - 2.2 8.2 9.5 0.49 10.3 5.8 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_UBOX PF13445.6 KZN93532.1 - 2.9 8.0 5.7 6.5 6.9 5.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 KZN93532.1 - 6.4 6.6 11.0 5.7 6.8 0.5 2.7 2 1 1 3 3 2 0 RING/Ubox like zinc-binding domain DEAD_2 PF06733.15 KZN93533.1 - 1.6e-56 190.7 0.1 2.9e-56 189.9 0.1 1.5 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 KZN93533.1 - 1.2e-49 168.5 1.8 1.1e-44 152.3 0.5 2.6 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 KZN93533.1 - 2.2e-43 148.4 0.0 5.7e-43 147.0 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 KZN93533.1 - 5.6e-05 23.2 0.0 0.0038 17.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KZN93533.1 - 0.0048 17.2 1.0 1.2 9.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain DEAD PF00270.29 KZN93533.1 - 0.0092 15.8 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.9 KZN93533.1 - 0.045 13.0 0.0 2 7.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.23 KZN93533.1 - 0.07 11.8 0.0 0.44 9.2 0.0 1.9 1 1 0 1 1 1 0 SNF2 family N-terminal domain ADH_N PF08240.12 KZN93534.1 - 3.1e-29 101.0 0.1 5.5e-29 100.2 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN93534.1 - 2.1e-16 60.1 0.0 3.3e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KZN93534.1 - 0.00065 19.6 0.3 0.0011 18.8 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.6 KZN93534.1 - 0.0042 18.2 0.0 0.0082 17.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RNA_pol_Rpb1_5 PF04998.17 KZN93535.1 - 5.4e-87 291.6 0.2 1.1e-86 290.6 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KZN93535.1 - 7e-67 224.8 0.1 1.6e-66 223.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KZN93535.1 - 5.4e-31 107.7 0.0 9.8e-30 103.6 0.0 3.0 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 KZN93535.1 - 8.7e-28 97.5 2.0 4.3e-27 95.3 0.0 3.0 3 1 0 3 3 3 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 KZN93535.1 - 4.1e-16 58.9 0.0 4.1e-16 58.9 0.0 2.8 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 4 PRP3 PF08572.10 KZN93536.1 - 3.2e-70 236.3 11.6 3.2e-70 236.3 11.6 1.6 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KZN93536.1 - 9.8e-47 158.7 0.0 9.8e-47 158.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Gar1 PF04410.14 KZN93537.1 - 1.3e-45 154.9 1.1 1.3e-45 154.9 1.1 2.5 3 1 1 4 4 4 1 Gar1/Naf1 RNA binding region Cwf_Cwc_15 PF04889.12 KZN93537.1 - 7.3 6.2 29.6 0.056 13.2 12.3 2.9 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein Glyco_transf_22 PF03901.17 KZN93538.1 - 5.9e-83 279.4 20.1 6.8e-83 279.2 20.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3445 PF11927.8 KZN93539.1 - 2.3e-84 282.5 0.0 2.8e-84 282.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Exo5 PF09810.9 KZN93540.1 - 2.8e-142 474.6 0.0 3.4e-142 474.3 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 KZN93540.1 - 0.014 15.4 0.0 10 5.9 0.1 3.1 2 1 0 2 2 2 0 PD-(D/E)XK nuclease superfamily Mpv17_PMP22 PF04117.12 KZN93541.1 - 1.3e-15 57.3 0.4 1.3e-15 57.3 0.4 2.0 3 0 0 3 3 3 1 Mpv17 / PMP22 family MFS_1 PF07690.16 KZN93542.1 - 2.5e-39 135.2 46.3 1.5e-38 132.6 41.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Histone PF00125.24 KZN93543.1 - 1e-51 174.7 2.5 1.1e-51 174.6 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KZN93543.1 - 6e-06 26.6 0.0 9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KZN93543.1 - 4.9e-05 23.4 0.5 7.4e-05 22.8 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KZN93543.1 - 6.5e-05 23.5 1.2 7.7e-05 23.3 1.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KZN93543.1 - 0.0032 17.7 0.3 0.0065 16.7 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KZN93543.1 - 0.026 14.6 0.2 0.042 13.9 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KZN93544.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KZN93544.1 - 2.4e-05 24.7 0.1 2.8e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KZN93544.1 - 7.2e-05 22.9 0.1 0.0001 22.4 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KZN93544.1 - 0.0002 21.6 0.1 0.00035 20.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KZN93544.1 - 0.0004 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KZN93544.1 - 0.0085 16.2 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KZN93544.1 - 0.031 14.3 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KZN93544.1 - 0.052 13.3 0.2 0.064 13.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 KZN93544.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region BTB PF00651.31 KZN93545.1 - 4.3e-11 43.0 0.0 2.2e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain zf-C2H2 PF00096.26 KZN93546.1 - 3.9e-08 33.3 19.2 3.4e-05 24.1 1.1 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KZN93546.1 - 2.4e-06 27.9 13.3 0.0098 16.7 0.7 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 KZN93546.1 - 1 9.7 7.9 1.6 9.0 2.3 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 KZN93546.1 - 5 7.2 7.2 0.33 11.0 1.8 1.9 2 0 0 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 KZN93546.1 - 5 7.7 19.2 2.8 8.5 1.5 4.7 5 0 0 5 5 5 0 Zinc-finger double domain zf-C2H2 PF00096.26 KZN93547.1 - 0.0012 19.2 21.8 0.0024 18.2 2.8 4.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KZN93547.1 - 0.03 15.2 20.1 0.13 13.2 2.2 4.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KZN93547.1 - 0.18 12.3 4.6 0.72 10.4 4.6 2.1 1 0 0 1 1 1 0 Zinc-finger double domain DUF2841 PF11001.8 KZN93548.1 - 1.2e-46 157.8 0.7 1.9e-46 157.1 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Sulfotransfer_4 PF17784.1 KZN93549.1 - 7.5e-52 176.3 0.0 8.8e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KZN93549.1 - 5.1e-07 30.3 0.0 0.00054 20.4 0.0 2.6 2 1 1 3 3 3 2 Sulfotransferase family OAD_gamma PF04277.13 KZN93550.1 - 0.066 13.8 2.5 0.18 12.4 2.5 1.7 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF3087 PF11286.8 KZN93550.1 - 0.81 9.1 2.5 0.53 9.7 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) p450 PF00067.22 KZN93551.1 - 1.7e-62 211.7 0.0 2.3e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 EPSP_synthase PF00275.20 KZN93552.1 - 4.6e-128 427.5 0.0 8.9e-128 426.5 0.0 1.4 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KZN93552.1 - 1e-97 326.4 0.0 1.8e-97 325.6 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 KZN93552.1 - 6.8e-58 196.6 0.0 1.4e-57 195.6 0.0 1.6 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KZN93552.1 - 9.8e-41 139.5 0.1 3.4e-40 137.7 0.0 1.9 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KZN93552.1 - 4.1e-24 84.6 0.0 9.5e-24 83.5 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KZN93552.1 - 2.3e-07 30.5 0.5 8.4e-07 28.6 0.1 2.2 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH_2 PF13685.6 KZN93552.1 - 2.5e-06 27.4 0.1 7.5e-06 25.8 0.1 1.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 KZN93552.1 - 0.00024 21.2 0.0 0.00096 19.2 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AAA_16 PF13191.6 KZN93552.1 - 0.069 13.5 0.1 0.22 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 KZN93552.1 - 0.12 12.9 0.0 0.35 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KZN93552.1 - 0.13 11.9 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Uso1_p115_head PF04869.14 KZN93554.1 - 1.4e-108 362.7 0.0 5.8e-108 360.7 0.0 2.1 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 KZN93554.1 - 1.2e-20 74.1 34.9 1.2e-20 74.1 34.9 5.6 1 1 3 4 4 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region Spc7 PF08317.11 KZN93554.1 - 8.2e-06 24.9 85.7 0.00015 20.8 18.5 3.8 1 1 3 4 4 4 3 Spc7 kinetochore protein Filament PF00038.21 KZN93554.1 - 1.7e-05 24.6 32.4 1.7e-05 24.6 32.4 4.6 1 1 3 4 4 4 2 Intermediate filament protein Golgin_A5 PF09787.9 KZN93554.1 - 0.0002 21.0 82.8 0.0014 18.2 11.0 4.5 1 1 3 4 4 4 2 Golgin subfamily A member 5 FAM184 PF15665.5 KZN93554.1 - 0.00038 20.3 83.6 0.007 16.2 9.9 4.3 1 1 4 5 5 4 4 Family with sequence similarity 184, A and B TRAF_BIRC3_bd PF16673.5 KZN93554.1 - 0.001 18.8 4.6 0.0082 15.9 0.4 5.8 5 2 2 7 7 6 2 TNF receptor-associated factor BIRC3 binding domain MAD PF05557.13 KZN93554.1 - 0.0012 17.4 5.3 0.0012 17.4 5.3 3.9 1 1 2 3 3 3 1 Mitotic checkpoint protein DUF1664 PF07889.12 KZN93554.1 - 0.0028 17.7 6.4 0.0028 17.7 6.4 6.4 1 1 6 7 7 7 3 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 KZN93554.1 - 0.0032 17.6 18.3 0.0032 17.6 18.3 6.4 1 1 3 5 5 4 3 Tropomyosin like Phage_GP20 PF06810.11 KZN93554.1 - 0.0034 17.2 3.8 0.0034 17.2 3.8 6.7 1 1 6 7 7 5 2 Phage minor structural protein GP20 Jnk-SapK_ap_N PF09744.9 KZN93554.1 - 0.0047 17.2 12.2 0.0047 17.2 12.2 5.5 1 1 4 5 5 4 1 JNK_SAPK-associated protein-1 ATG16 PF08614.11 KZN93554.1 - 0.006 16.8 90.7 0.091 13.0 23.3 4.7 1 1 3 4 4 3 3 Autophagy protein 16 (ATG16) DUF3584 PF12128.8 KZN93554.1 - 0.0076 13.8 84.0 0.008 13.8 40.5 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.9 KZN93554.1 - 0.037 14.0 79.1 0.012 15.6 22.6 5.1 2 1 4 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pox_A_type_inc PF04508.12 KZN93554.1 - 0.054 13.4 5.5 26 4.9 0.1 6.3 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat LemA PF04011.12 KZN93554.1 - 0.18 11.7 0.1 0.18 11.7 0.1 6.1 2 1 2 6 6 6 0 LemA family Myosin_tail_1 PF01576.19 KZN93554.1 - 0.2 9.4 88.6 0.12 10.2 62.7 2.1 1 1 1 2 2 2 0 Myosin tail TPR_MLP1_2 PF07926.12 KZN93554.1 - 0.24 11.4 100.8 0.65 10.1 16.6 6.3 2 2 4 6 6 6 0 TPR/MLP1/MLP2-like protein Tup_N PF08581.10 KZN93554.1 - 0.28 11.5 0.0 0.28 11.5 0.0 8.6 4 2 4 8 8 6 0 Tup N-terminal CtIP_N PF10482.9 KZN93554.1 - 0.35 10.9 47.6 0.032 14.3 1.7 7.6 2 1 4 6 6 6 0 Tumour-suppressor protein CtIP N-terminal domain Surfac_D-trimer PF09006.11 KZN93554.1 - 0.37 10.7 18.4 3.2 7.7 0.0 6.4 6 1 1 7 7 5 0 Lung surfactant protein D coiled-coil trimerisation FUSC PF04632.12 KZN93554.1 - 0.89 8.0 38.3 0.23 10.0 15.2 3.6 1 1 3 4 4 4 0 Fusaric acid resistance protein family Cast PF10174.9 KZN93554.1 - 1.7 6.8 75.3 0.049 11.9 38.2 2.8 1 1 2 3 3 3 0 RIM-binding protein of the cytomatrix active zone gpW PF02831.15 KZN93554.1 - 1.8 8.5 0.0 1.8 8.5 0.0 4.4 5 0 0 5 5 2 0 gpW AFP_2 PF18815.1 KZN93554.1 - 2.2 8.6 7.0 18 5.7 0.2 3.9 2 1 1 3 3 3 0 Bacterial antifreeze protein repeat Baculo_PEP_C PF04513.12 KZN93554.1 - 3 7.9 45.2 0.17 11.9 2.4 6.0 2 1 4 6 6 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4200 PF13863.6 KZN93554.1 - 9.8 6.6 78.6 0.042 14.3 6.8 6.4 2 2 4 6 6 5 0 Domain of unknown function (DUF4200) XRN_M PF17846.1 KZN93555.1 - 3e-147 491.2 0.4 4.6e-146 487.2 0.0 2.6 2 1 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 KZN93555.1 - 6.8e-99 330.2 1.0 2.8e-98 328.2 0.0 2.0 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 KZN93555.1 - 0.18 11.9 4.2 0.34 11.1 4.2 1.5 1 0 0 1 1 1 0 Zinc knuckle tRNA-synt_1 PF00133.22 KZN93556.1 - 2.5e-223 742.7 0.0 3.5e-223 742.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KZN93556.1 - 7e-24 84.5 0.0 1.8e-23 83.2 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KZN93556.1 - 1.1e-14 54.1 0.4 1.4e-06 27.3 0.0 4.2 4 1 0 4 4 4 3 tRNA synthetases class I (M) CX9C PF16860.5 KZN93557.1 - 0.00012 22.0 1.2 0.00015 21.7 1.2 1.2 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 KZN93557.1 - 0.019 15.0 2.1 0.027 14.5 2.1 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Rota_NSP4 PF01452.16 KZN93557.1 - 0.025 14.2 0.2 0.028 14.1 0.2 1.0 1 0 0 1 1 1 0 Rotavirus non structural protein NDUF_B7 PF05676.13 KZN93557.1 - 0.029 14.1 1.3 3.7 7.3 0.1 2.1 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Sfi1 PF08457.10 KZN93558.1 - 1.6e-210 700.5 93.5 1.5e-209 697.3 84.6 2.1 1 1 1 2 2 2 2 Sfi1 spindle body protein Rav1p_C PF12234.8 KZN93559.1 - 9.5e-282 936.1 0.0 1.3e-281 935.7 0.0 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.32 KZN93559.1 - 0.02 15.7 4.4 0.71 10.8 0.0 4.8 6 0 0 6 6 6 0 WD domain, G-beta repeat p450 PF00067.22 KZN93560.1 - 2.3e-58 198.1 0.0 2.8e-58 197.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tir_receptor_C PF07489.11 KZN93561.1 - 0.0042 17.1 2.1 0.0042 17.1 2.1 1.8 2 0 0 2 2 2 1 Translocated intimin receptor (Tir) C-terminus SGL PF08450.12 KZN93563.1 - 9e-26 90.9 0.7 1.9e-25 89.9 0.7 1.6 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KZN93563.1 - 1.1e-05 25.4 0.0 2.8e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.20 KZN93563.1 - 2.8e-05 24.2 0.1 0.0012 19.0 0.0 2.6 1 1 0 2 2 2 1 Arylesterase NHL PF01436.21 KZN93563.1 - 0.021 14.8 0.1 0.43 10.7 0.0 2.8 2 0 0 2 2 2 0 NHL repeat MFS18 PF17352.2 KZN93564.1 - 0.0089 16.4 0.7 0.0089 16.4 0.7 2.6 2 1 0 2 2 2 1 Male Flower Specific protein 18 SKG6 PF08693.10 KZN93564.1 - 0.018 14.4 0.1 0.037 13.4 0.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Gram_pos_anchor PF00746.21 KZN93564.1 - 0.019 14.9 1.7 0.038 13.9 1.7 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Yip1 PF04893.17 KZN93564.1 - 0.051 13.3 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 Yip1 domain Nitrate_red_gam PF02665.14 KZN93564.1 - 0.076 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit DUF5305 PF17231.2 KZN93564.1 - 0.08 12.3 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) p450 PF00067.22 KZN93565.1 - 2.6e-74 250.6 0.0 3.1e-74 250.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF440 PF04269.12 KZN93566.1 - 0.096 13.0 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF440 AAA_16 PF13191.6 KZN93568.1 - 1.4e-05 25.6 2.3 5.5e-05 23.6 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 KZN93568.1 - 0.0019 18.1 0.1 0.58 10.1 0.0 3.1 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KZN93568.1 - 0.0024 18.2 3.2 0.0081 16.4 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_19 PF13245.6 KZN93568.1 - 0.0024 18.2 0.5 0.032 14.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain TPR_12 PF13424.6 KZN93568.1 - 0.0035 17.6 29.5 3.3 8.1 0.1 9.8 11 1 0 11 11 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 KZN93568.1 - 0.0045 16.9 8.6 17 5.7 0.2 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 KZN93568.1 - 0.011 15.8 12.8 2.8 8.3 0.0 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Forkhead PF00250.18 KZN93568.1 - 0.015 15.5 0.1 0.085 13.1 0.1 2.3 1 0 0 1 1 1 0 Forkhead domain NB-ARC PF00931.22 KZN93568.1 - 0.026 13.7 0.0 0.082 12.1 0.0 1.8 1 0 0 1 1 1 0 NB-ARC domain TPR_19 PF14559.6 KZN93568.1 - 0.061 13.8 10.1 1.6 9.3 0.3 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat DRY_EERY PF09750.9 KZN93568.1 - 0.1 12.8 0.4 0.39 11.0 0.4 2.0 1 0 0 1 1 1 0 Alternative splicing regulator ABC_tran PF00005.27 KZN93568.1 - 0.18 12.3 0.5 2.2 8.8 0.0 3.0 2 0 0 2 2 2 0 ABC transporter YfdX PF10938.8 KZN93568.1 - 4.7 7.1 7.4 1.6 8.7 1.5 3.2 3 0 0 3 3 3 0 YfdX protein TPR_10 PF13374.6 KZN93568.1 - 7 6.7 23.5 77 3.3 0.0 9.6 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_14 PF13428.6 KZN93568.1 - 7.4 7.7 19.2 52 5.0 0.0 8.0 9 0 0 9 9 5 0 Tetratricopeptide repeat Pkinase PF00069.25 KZN93569.1 - 2e-14 53.6 0.0 6e-14 52.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN93569.1 - 2.8e-10 39.9 0.0 1.5e-09 37.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KZN93569.1 - 0.13 11.6 0.2 0.24 10.7 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_transf_25 PF01755.17 KZN93570.1 - 5.7e-09 36.1 0.0 8.7e-08 32.3 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) EamA PF00892.20 KZN93570.1 - 2.5e-06 27.7 10.1 2.5e-06 27.7 10.1 2.7 3 0 0 3 3 3 1 EamA-like transporter family TPT PF03151.16 KZN93570.1 - 0.00046 19.6 20.7 0.00067 19.1 20.7 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family SPC25 PF06703.11 KZN93570.1 - 0.12 12.2 0.1 0.34 10.7 0.1 1.8 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) TssN PF17555.2 KZN93570.1 - 3.1 7.1 11.8 0.3 10.4 6.1 2.0 1 1 0 2 2 2 0 Type VI secretion system, TssN MFS_1 PF07690.16 KZN93571.1 - 2.6e-39 135.1 31.2 2.6e-39 135.1 31.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN93571.1 - 1.2e-09 37.5 30.9 2.2e-09 36.7 30.9 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter Kin17_mid PF10357.9 KZN93572.1 - 4.6e-51 172.0 1.0 7.7e-51 171.3 1.0 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 KZN93572.1 - 0.01 16.2 3.7 0.024 15.0 3.7 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KZN93572.1 - 0.031 14.6 2.3 0.087 13.2 0.3 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KZN93572.1 - 0.034 14.5 3.3 0.083 13.2 3.3 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Ribosomal_S18 PF01084.20 KZN93572.1 - 0.095 12.9 0.7 0.26 11.5 0.7 1.7 1 0 0 1 1 1 0 Ribosomal protein S18 Actin PF00022.19 KZN93573.1 - 1.1e-20 73.7 0.0 2.6e-17 62.6 0.0 3.1 3 0 0 3 3 3 3 Actin RhoGAP-FF1 PF16512.5 KZN93573.1 - 0.052 14.2 0.0 0.1 13.3 0.0 1.4 1 0 0 1 1 1 0 p190-A and -B Rho GAPs FF domain CBFD_NFYB_HMF PF00808.23 KZN93574.1 - 4.5e-18 65.3 0.3 7.9e-18 64.5 0.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KZN93574.1 - 5.9e-08 33.1 1.3 1.5e-07 31.9 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KZN93574.1 - 0.0083 16.1 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated DUF5333 PF17267.2 KZN93574.1 - 0.013 15.6 0.8 0.018 15.2 0.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5333) SPOB_ab PF14682.6 KZN93574.1 - 0.027 14.6 0.4 0.036 14.1 0.4 1.2 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal TFIID-31kDa PF02291.15 KZN93574.1 - 0.078 13.1 0.0 0.15 12.1 0.0 1.6 1 1 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit YolD PF08863.10 KZN93574.1 - 0.43 10.7 7.1 0.4 10.8 5.5 1.7 2 0 0 2 2 2 0 YolD-like protein adh_short PF00106.25 KZN93575.1 - 6.7e-45 152.9 0.3 7.9e-45 152.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN93575.1 - 1.6e-31 109.7 0.1 2e-31 109.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN93575.1 - 1.5e-13 51.1 0.4 2.4e-13 50.4 0.4 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KZN93575.1 - 3.9e-05 23.6 0.4 6e-05 23.0 0.4 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KZN93575.1 - 0.001 18.6 0.1 0.004 16.7 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KZN93575.1 - 0.014 15.5 0.1 0.022 14.8 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1776 PF08643.10 KZN93575.1 - 0.027 13.8 0.0 0.035 13.5 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NmrA PF05368.13 KZN93575.1 - 0.065 12.8 0.7 0.12 11.9 0.5 1.6 2 0 0 2 2 2 0 NmrA-like family F420_oxidored PF03807.17 KZN93575.1 - 0.13 12.8 0.0 0.35 11.5 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.24 KZN93576.1 - 1.2e-38 133.6 0.1 1.4e-38 133.4 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KZN93576.1 - 0.0014 19.2 0.1 0.38 11.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase KHA PF11834.8 KZN93576.1 - 0.017 15.2 0.2 0.061 13.4 0.0 1.9 2 0 0 2 2 2 0 KHA, dimerisation domain of potassium ion channel NAD_binding_8 PF13450.6 KZN93576.1 - 0.068 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Mqo PF06039.15 KZN93576.1 - 0.16 10.5 0.0 0.25 9.8 0.0 1.3 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) zf-CCCH PF00642.24 KZN93577.1 - 3e-08 33.4 20.0 3e-07 30.2 2.5 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KZN93577.1 - 0.0058 16.7 3.3 0.0058 16.7 3.3 3.3 3 0 0 3 3 3 1 Zinc finger domain Torus PF16131.5 KZN93577.1 - 0.007 17.0 2.3 0.45 11.2 0.3 2.5 2 0 0 2 2 2 1 Torus domain RRM_1 PF00076.22 KZN93577.1 - 0.048 13.5 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SCRG1 PF15224.6 KZN93577.1 - 0.17 12.0 3.8 0.17 12.0 0.1 2.3 2 0 0 2 2 2 0 Scrapie-responsive protein 1 zf-CCCH_3 PF15663.5 KZN93577.1 - 2.2 8.5 7.8 0.4 10.9 1.4 2.4 2 2 0 2 2 2 0 Zinc-finger containing family SMC_Nse1 PF07574.13 KZN93578.1 - 1.2e-66 224.4 0.2 1.5e-66 224.0 0.2 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 KZN93578.1 - 1.9e-14 53.7 11.1 3.2e-14 53.0 11.1 1.4 1 0 0 1 1 1 1 RING-like domain zf-ANAPC11 PF12861.7 KZN93578.1 - 0.0019 18.2 2.3 0.0032 17.5 2.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KZN93578.1 - 0.01 16.2 9.1 0.018 15.4 9.1 1.4 1 0 0 1 1 1 0 Ring finger domain DUF4862 PF16154.5 KZN93578.1 - 0.026 13.9 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4862) DUF4796 PF16044.5 KZN93578.1 - 0.039 13.5 0.1 0.093 12.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) zf-Di19 PF05605.12 KZN93578.1 - 0.078 13.3 0.9 0.16 12.3 0.9 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding IL4 PF00727.18 KZN93578.1 - 0.12 12.6 1.3 0.26 11.5 0.5 1.9 2 0 0 2 2 2 0 Interleukin 4 FANCL_C PF11793.8 KZN93578.1 - 0.25 11.6 6.8 0.7 10.1 6.8 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4 PF00097.25 KZN93578.1 - 0.31 10.9 9.8 0.57 10.1 9.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KZN93578.1 - 0.68 10.3 6.3 1.5 9.2 6.3 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain YdjO PF14169.6 KZN93578.1 - 0.72 9.6 7.0 1.8 8.4 7.0 1.6 1 0 0 1 1 1 0 Cold-inducible protein YdjO Zn_ribbon_17 PF17120.5 KZN93578.1 - 0.76 9.4 6.1 1.3 8.7 6.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 KZN93578.1 - 0.84 9.5 8.7 1.5 8.7 8.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYDLN_acid PF09538.10 KZN93578.1 - 2.3 8.9 5.1 0.42 11.3 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-HC5HC2H PF13771.6 KZN93578.1 - 3.1 8.1 9.6 16 5.8 9.9 2.0 1 1 1 2 2 2 0 PHD-like zinc-binding domain Glyco_hydro_65N PF03636.15 KZN93579.1 - 2.7e-33 115.5 0.0 7.3e-33 114.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.15 KZN93579.1 - 1.8e-25 89.6 3.0 4e-19 68.7 0.5 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65C PF03633.15 KZN93579.1 - 0.001 18.9 0.1 0.0025 17.7 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain Catalase PF00199.19 KZN93580.1 - 2.5e-163 543.7 0.0 3.1e-163 543.4 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 KZN93580.1 - 4.4e-50 169.3 1.1 7.1e-50 168.6 1.1 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 KZN93580.1 - 3.8e-18 65.4 0.1 9.8e-18 64.1 0.1 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive Acetyltransf_1 PF00583.25 KZN93581.1 - 3.1e-07 30.6 0.0 4.5e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KZN93581.1 - 1.4e-05 25.4 0.0 2.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KZN93581.1 - 2.8e-05 24.1 0.0 4.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KZN93581.1 - 0.051 13.7 0.0 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Cupin_2 PF07883.11 KZN93582.1 - 2.1e-09 37.0 0.2 6.8e-05 22.5 0.0 2.5 2 0 0 2 2 2 2 Cupin domain Na_Ca_ex PF01699.24 KZN93583.1 - 9.2e-30 103.6 36.9 1.7e-16 60.5 13.3 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF872 PF05915.12 KZN93583.1 - 0.68 10.1 2.8 12 6.1 0.9 2.8 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF4699 PF15770.5 KZN93584.1 - 0.019 14.7 6.1 0.031 14.1 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4699) DUF3246 PF11596.8 KZN93585.1 - 0.022 14.2 2.5 0.05 13.0 2.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3246) MetJ PF01340.20 KZN93585.1 - 0.11 12.5 0.3 0.16 12.0 0.0 1.4 2 0 0 2 2 2 0 Met Apo-repressor, MetJ DAO PF01266.24 KZN93586.1 - 1.5e-39 136.6 0.0 2.3e-39 136.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KZN93586.1 - 4.1e-06 26.9 0.0 1.6e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KZN93586.1 - 5.5e-06 25.9 0.1 0.00063 19.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KZN93586.1 - 4.2e-05 22.9 0.0 0.06 12.6 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KZN93586.1 - 0.00021 20.1 0.0 0.13 11.0 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 KZN93586.1 - 0.00091 19.7 0.0 0.17 12.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KZN93586.1 - 0.0023 18.0 0.0 0.0038 17.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.14 KZN93586.1 - 0.0079 15.1 0.0 0.11 11.3 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase ApbA PF02558.16 KZN93586.1 - 0.024 14.3 0.0 0.064 12.9 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 KZN93586.1 - 0.051 12.7 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Glu_dehyd_C PF16912.5 KZN93586.1 - 0.053 13.0 0.0 0.099 12.1 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Thi4 PF01946.17 KZN93586.1 - 0.053 12.8 0.0 0.18 11.0 0.0 1.7 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.18 KZN93586.1 - 0.053 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.19 KZN93586.1 - 0.06 12.6 0.0 0.098 11.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 KZN93586.1 - 0.084 11.9 0.0 4.7 6.2 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Fungal_trans PF04082.18 KZN93587.1 - 3.7e-11 42.5 0.3 5.5e-11 42.0 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rieske PF00355.26 KZN93588.1 - 5.9e-15 55.0 0.0 1.1e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.19 KZN93588.1 - 8.6e-14 52.0 2.8 6.4e-11 42.6 0.0 2.6 3 0 0 3 3 3 2 Ring hydroxylating alpha subunit (catalytic domain) Zn_clus PF00172.18 KZN93589.1 - 1.5e-09 37.8 9.1 3.7e-09 36.5 9.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN93589.1 - 2.4e-07 30.1 1.7 4.4e-07 29.2 1.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.13 KZN93590.1 - 1.1e-70 237.4 10.8 1.1e-70 237.4 10.8 2.0 1 1 1 2 2 2 1 RTA1 like protein SecA_DEAD PF07517.14 KZN93590.1 - 0.21 10.8 0.1 0.29 10.4 0.1 1.1 1 0 0 1 1 1 0 SecA DEAD-like domain PalH PF08733.10 KZN93590.1 - 3.7 6.4 17.1 0.52 9.3 5.7 2.1 1 1 0 2 2 2 0 PalH/RIM21 RTA1 PF04479.13 KZN93592.1 - 1.3e-75 253.6 8.1 1.3e-75 253.6 8.1 1.4 2 0 0 2 2 2 1 RTA1 like protein DUF5359 PF17313.2 KZN93592.1 - 2.8 8.0 6.6 3.4 7.7 1.4 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5359) Glyco_hydro_10 PF00331.20 KZN93593.1 - 2.2e-72 243.9 0.0 2.6e-72 243.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.15 KZN93593.1 - 0.0071 15.7 0.1 0.011 15.1 0.1 1.2 1 0 0 1 1 1 1 Beta-galactosidase Glyco_transf_28 PF03033.20 KZN93594.1 - 3.3e-24 85.5 0.0 6.5e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain ATG_C PF09333.11 KZN93594.1 - 0.004 17.5 0.2 0.019 15.3 0.0 2.2 2 1 1 3 3 3 1 Autophagy-related protein C terminal domain UDPGT PF00201.18 KZN93594.1 - 0.0071 15.2 0.1 0.014 14.2 0.1 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase VPS13_C PF16909.5 KZN93594.1 - 0.022 14.6 0.1 0.058 13.2 0.1 1.7 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal Glyco_tran_28_C PF04101.16 KZN93594.1 - 0.025 14.6 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Oxidored_FMN PF00724.20 KZN93595.1 - 2.1e-88 296.8 0.0 2.5e-88 296.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 KZN93595.1 - 0.0042 16.6 0.0 0.54 9.7 0.0 2.5 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Ribonuc_L-PSP PF01042.21 KZN93596.1 - 1.4e-18 67.0 0.0 1.7e-18 66.8 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP MFS_1 PF07690.16 KZN93597.1 - 1.2e-30 106.7 35.1 1.2e-30 106.7 35.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily AA_permease_2 PF13520.6 KZN93598.1 - 4.7e-50 170.6 47.9 5.7e-50 170.4 47.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN93598.1 - 3.8e-18 65.3 39.3 5.4e-18 64.8 39.3 1.1 1 0 0 1 1 1 1 Amino acid permease Arylsulfotran_2 PF14269.6 KZN93599.1 - 8.4e-56 189.5 3.2 1.1e-55 189.1 3.2 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KZN93599.1 - 2.8e-13 49.6 1.3 7.7e-13 48.1 1.3 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ PF01011.21 KZN93599.1 - 0.81 9.7 4.6 16 5.7 0.1 3.6 5 0 0 5 5 5 0 PQQ enzyme repeat p450 PF00067.22 KZN93600.1 - 1.1e-76 258.4 0.0 1.4e-76 258.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 APH PF01636.23 KZN93601.1 - 1.5e-06 28.4 0.0 3.4e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family TilS PF09179.11 KZN93602.1 - 0.94 10.0 3.7 19 5.9 3.7 2.4 1 1 0 1 1 1 0 TilS substrate binding domain Kdo PF06293.14 KZN93604.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SH3_4 PF06347.13 KZN93604.1 - 0.18 11.7 0.5 0.32 10.9 0.5 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain DUF2007 PF09413.10 KZN93606.1 - 0.013 15.6 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein AAA_12 PF13087.6 KZN93607.1 - 1.5e-23 83.5 0.0 2.9e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KZN93607.1 - 1.2e-07 31.8 0.0 2.9e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KZN93607.1 - 2.9e-05 23.8 0.0 7.4e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KZN93607.1 - 0.017 14.8 0.0 0.047 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain BPA_C PF18040.1 KZN93607.1 - 0.023 14.6 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 beta porphyranase A C-terminal AAA_16 PF13191.6 KZN93607.1 - 0.028 14.8 0.0 0.091 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 KZN93607.1 - 0.038 14.3 0.1 0.18 12.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KZN93607.1 - 0.18 11.0 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF3176 PF11374.8 KZN93608.1 - 1.6e-34 118.3 0.4 2.1e-33 114.7 0.6 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Proton_antipo_M PF00361.20 KZN93608.1 - 0.43 9.7 3.0 0.89 8.7 3.0 1.4 1 0 0 1 1 1 0 Proton-conducting membrane transporter BatD PF13584.6 KZN93609.1 - 0.002 17.0 0.0 0.003 16.5 0.0 1.2 1 0 0 1 1 1 1 Oxygen tolerance SARAF PF06682.12 KZN93609.1 - 0.0045 16.7 1.2 0.011 15.4 0.2 1.7 1 1 1 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis DUF4381 PF14316.6 KZN93609.1 - 0.0051 17.0 0.0 0.008 16.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) Phyto-Amp PF15438.6 KZN93609.1 - 0.24 11.2 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 Antigenic membrane protein of phytoplasma Asparaginase_II PF06089.12 KZN93611.1 - 2.2e-116 388.4 0.7 2.5e-116 388.2 0.7 1.0 1 0 0 1 1 1 1 L-asparaginase II ThrE PF06738.12 KZN93612.1 - 8e-75 251.3 21.7 2.8e-69 233.2 4.6 2.9 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KZN93612.1 - 3e-12 46.8 11.4 3e-12 46.8 11.4 2.8 3 0 0 3 3 3 1 Threonine/Serine exporter, ThrE FSH1 PF03959.13 KZN93613.1 - 9.4e-28 97.3 0.0 1.1e-27 97.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KZN93613.1 - 0.016 15.8 0.1 0.029 15.0 0.1 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family KR PF08659.10 KZN93614.1 - 4.5e-60 202.6 0.0 1.4e-59 201.0 0.0 1.9 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 KZN93614.1 - 1.8e-58 198.1 0.0 3.6e-58 197.2 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KZN93614.1 - 2.4e-43 148.9 0.1 6.9e-43 147.4 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain ketoacyl-synt PF00109.26 KZN93614.1 - 4.4e-39 134.6 1.6 9.1e-39 133.5 1.6 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KZN93614.1 - 3.5e-38 130.2 0.0 1.4e-37 128.3 0.0 2.2 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KZN93614.1 - 7.1e-15 55.4 0.0 2.3e-14 53.8 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KZN93614.1 - 3.5e-11 42.9 0.1 1e-10 41.4 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN93614.1 - 5.4e-08 32.7 0.2 2.3e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_23 PF13489.6 KZN93614.1 - 8.4e-08 32.2 0.0 1.8e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN93614.1 - 2e-07 31.7 0.0 6e-07 30.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN93614.1 - 8.5e-07 29.6 0.0 4.1e-06 27.4 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN93614.1 - 1.9e-06 28.4 0.0 9.3e-06 26.2 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.25 KZN93614.1 - 7e-05 23.1 0.0 0.0002 21.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site SAT PF16073.5 KZN93614.1 - 9.4e-05 22.3 1.9 0.00017 21.4 0.1 2.4 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Thiolase_N PF00108.23 KZN93614.1 - 0.00011 21.7 0.1 0.00025 20.5 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.12 KZN93614.1 - 0.0015 18.4 0.0 0.0038 17.1 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_31 PF13847.6 KZN93614.1 - 0.0044 16.8 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ACP_syn_III PF08545.10 KZN93614.1 - 0.014 15.2 0.6 0.081 12.8 0.2 2.7 3 0 0 3 3 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ubie_methyltran PF01209.18 KZN93614.1 - 0.017 14.5 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Polysacc_synt_2 PF02719.15 KZN93614.1 - 0.04 13.0 0.0 0.077 12.1 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ABC2_membrane PF01061.24 KZN93615.1 - 1.1e-82 276.6 46.8 2e-45 154.8 17.5 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KZN93615.1 - 5.6e-40 137.0 0.0 8.8e-19 68.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KZN93615.1 - 2e-27 94.9 0.2 2e-27 94.9 0.2 3.6 4 0 0 4 4 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 KZN93615.1 - 6.4e-07 28.8 42.4 0.00014 21.2 19.6 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.6 KZN93615.1 - 2.6e-05 23.9 0.0 0.00085 18.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KZN93615.1 - 8.1e-05 22.9 0.1 1 9.6 0.0 3.4 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.6 KZN93615.1 - 9.5e-05 22.8 0.5 0.11 12.9 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 KZN93615.1 - 0.00013 22.1 0.0 0.24 11.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KZN93615.1 - 0.0005 19.8 1.9 0.085 12.6 0.1 3.5 3 0 0 3 3 3 1 P-loop containing region of AAA domain ABC_trans_N PF14510.6 KZN93615.1 - 0.001 19.7 0.1 0.0027 18.3 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_28 PF13521.6 KZN93615.1 - 0.0013 18.9 0.8 0.91 9.7 0.5 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KZN93615.1 - 0.0027 17.6 0.5 0.013 15.4 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KZN93615.1 - 0.006 17.1 0.0 2.5 8.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KZN93615.1 - 0.01 15.7 0.6 1.9 8.4 0.1 2.6 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 KZN93615.1 - 0.015 14.9 2.2 2 8.0 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 KZN93615.1 - 0.016 15.1 0.0 3.3 7.4 0.0 2.7 3 0 0 3 3 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KZN93615.1 - 0.06 13.8 0.0 18 5.8 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KZN93615.1 - 0.07 12.8 0.6 5.8 6.6 0.3 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KZN93615.1 - 0.13 12.7 0.4 7.1 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KZN93615.1 - 0.17 11.7 1.2 8.2 6.2 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 KZN93615.1 - 0.21 11.5 0.0 9.2 6.1 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain Zeta_toxin PF06414.12 KZN93615.1 - 0.32 10.2 1.0 5.6 6.2 0.3 2.3 2 0 0 2 2 2 0 Zeta toxin MFS_1 PF07690.16 KZN93616.1 - 2.8e-33 115.3 23.4 4.4e-33 114.7 23.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF5090 PF17009.5 KZN93616.1 - 0.032 14.2 1.4 0.11 12.5 1.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) IATP PF04568.12 KZN93617.1 - 1.5e-19 70.3 0.1 1.9e-19 69.9 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP TssO PF17561.2 KZN93617.1 - 0.046 13.8 0.5 0.053 13.6 0.5 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssO MFS_1 PF07690.16 KZN93618.1 - 5.6e-32 111.0 57.8 2.9e-29 102.1 47.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KZN93618.1 - 0.00019 20.1 36.7 0.011 14.3 6.6 3.2 1 1 2 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.24 KZN93618.1 - 0.0017 17.3 38.8 0.05 12.5 16.5 2.7 1 1 0 2 2 2 2 Sugar (and other) transporter Phage_holin_2_3 PF16080.5 KZN93618.1 - 1.4 8.8 6.5 1.4 8.7 0.3 3.4 3 0 0 3 3 3 0 Bacteriophage holin family HP1 Hamartin PF04388.12 KZN93620.1 - 0.35 9.5 6.2 0.43 9.2 6.2 1.0 1 0 0 1 1 1 0 Hamartin protein Zn_clus PF00172.18 KZN93621.1 - 1.3e-05 25.3 12.7 2.5e-05 24.3 12.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KZN93621.1 - 6.7e-05 21.9 0.0 0.00023 20.1 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Halo_GVPC PF05465.13 KZN93621.1 - 0.61 10.4 2.7 0.5 10.7 0.1 2.3 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat Lipase_2 PF01674.18 KZN93622.1 - 2.7e-07 30.4 0.0 4.7e-07 29.6 0.0 1.4 1 1 0 1 1 1 1 Lipase (class 2) Abhydrolase_1 PF00561.20 KZN93622.1 - 1.5e-05 24.8 0.1 7.5e-05 22.5 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KZN93622.1 - 5.1e-05 24.0 0.0 6.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 KZN93622.1 - 0.0034 17.3 0.0 0.049 13.5 0.0 2.0 2 0 0 2 2 2 1 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 KZN93622.1 - 0.0043 16.4 0.0 0.007 15.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KZN93622.1 - 0.015 15.2 0.0 0.31 10.9 0.0 2.1 1 1 0 1 1 1 0 Serine hydrolase DUF2974 PF11187.8 KZN93622.1 - 0.021 14.4 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF900 PF05990.12 KZN93622.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 KZN93622.1 - 0.11 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 KZN93622.1 - 0.17 11.8 0.0 0.41 10.5 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 3) HCV_env PF01539.17 KZN93622.1 - 0.17 11.5 0.0 0.4 10.4 0.0 1.6 1 0 0 1 1 1 0 Hepatitis C virus envelope glycoprotein E1 Hce2 PF14856.6 KZN93623.1 - 1.1e-20 73.8 0.4 7.7e-20 71.1 0.2 2.4 2 0 0 2 2 2 1 Pathogen effector; putative necrosis-inducing factor SSP160 PF06933.11 KZN93624.1 - 2.6 6.1 10.4 2.7 6.1 10.4 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DHC_N2 PF08393.13 KZN93625.1 - 0.016 14.4 0.8 0.036 13.2 0.2 1.8 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 2 APG6_N PF17675.1 KZN93625.1 - 1.1 9.8 10.6 3.5 8.2 4.1 2.7 3 0 0 3 3 3 0 Apg6 coiled-coil region Abhydrolase_4 PF08386.10 KZN93626.1 - 7.6e-27 93.4 0.0 1.8e-26 92.2 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KZN93626.1 - 3.1e-16 59.8 0.0 6.4e-11 42.4 0.0 2.6 2 1 0 2 2 2 2 alpha/beta hydrolase fold Aldolase_II PF00596.21 KZN93627.1 - 8.7e-49 166.0 0.1 1.2e-48 165.6 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain TIG_plexin PF17960.1 KZN93630.1 - 0.023 14.7 1.2 3.5 7.7 0.0 2.6 2 1 0 2 2 2 0 TIG domain adh_short PF00106.25 KZN93632.1 - 1.2e-38 132.5 0.1 2e-37 128.6 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN93632.1 - 3.4e-30 105.3 0.0 2.4e-17 63.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN93632.1 - 1.3e-06 28.5 0.1 8e-06 25.9 0.1 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KZN93632.1 - 0.00066 19.2 0.0 0.003 17.1 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 KZN93632.1 - 0.0039 17.9 0.0 0.0069 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KZN93632.1 - 0.11 12.5 0.1 6.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Zinc-binding dehydrogenase 3HCDH_N PF02737.18 KZN93632.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KZN93632.1 - 0.16 12.0 0.4 0.52 10.4 0.5 2.0 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Abhydrolase_3 PF07859.13 KZN93633.1 - 4.4e-51 173.7 0.0 6e-51 173.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KZN93633.1 - 1.6e-07 30.6 0.0 5.1e-07 28.9 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 KZN93633.1 - 0.0002 20.4 0.0 0.00026 20.0 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KZN93633.1 - 0.0016 18.0 0.0 0.082 12.4 0.0 2.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 KZN93633.1 - 0.02 13.6 0.0 0.041 12.5 0.0 1.5 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DLH PF01738.18 KZN93633.1 - 0.058 12.9 0.0 0.69 9.4 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Cyclase PF04199.13 KZN93634.1 - 8.1e-14 52.0 0.0 1.1e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Pyr_redox_3 PF13738.6 KZN93635.1 - 2.7e-15 56.4 0.0 3.2e-13 49.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KZN93635.1 - 2.8e-15 56.3 0.0 3.7e-14 52.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KZN93635.1 - 3.4e-12 45.6 0.0 1.5e-08 33.6 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KZN93635.1 - 1.5e-09 37.5 0.0 1e-07 31.4 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KZN93635.1 - 5.7e-09 36.1 0.1 2.4e-07 30.9 0.2 2.7 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KZN93635.1 - 3e-05 23.3 0.1 0.012 14.7 0.1 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KZN93635.1 - 9.8e-05 22.8 0.8 0.0072 16.9 0.2 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KZN93635.1 - 0.00023 20.5 0.4 0.074 12.3 0.0 2.8 3 0 0 3 3 3 2 Thi4 family DAO PF01266.24 KZN93635.1 - 0.00058 19.5 0.1 0.048 13.2 0.1 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KZN93635.1 - 0.00078 18.6 0.1 0.0013 17.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KZN93635.1 - 0.0034 16.5 0.5 0.11 11.5 0.3 2.8 2 1 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KZN93635.1 - 0.0092 16.0 2.9 3.6 7.6 0.7 3.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 KZN93635.1 - 0.035 14.5 0.2 0.45 11.0 0.1 2.8 2 2 0 2 2 2 0 Putative NAD(P)-binding FAD_oxidored PF12831.7 KZN93635.1 - 0.12 11.7 0.1 0.23 10.8 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KZN93635.1 - 0.22 10.2 0.7 2.7 6.6 0.2 2.4 3 0 0 3 3 3 0 HI0933-like protein adh_short_C2 PF13561.6 KZN93636.1 - 1.2e-56 191.9 0.1 1.5e-56 191.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN93636.1 - 6.3e-48 162.8 0.1 7.9e-48 162.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN93636.1 - 1.6e-10 41.2 0.1 1.6e-10 41.2 0.1 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KZN93636.1 - 0.011 15.2 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.23 KZN93636.1 - 0.021 14.9 0.2 0.034 14.2 0.2 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KZN93636.1 - 0.045 12.9 0.1 0.078 12.1 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ThiF PF00899.21 KZN93636.1 - 0.21 10.9 1.5 0.58 9.5 0.3 1.9 1 1 1 2 2 2 0 ThiF family Amidohydro_1 PF01979.20 KZN93637.1 - 4.9e-65 220.1 0.0 6e-65 219.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KZN93637.1 - 0.0017 17.9 0.4 0.37 10.2 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family DUF3466 PF11949.8 KZN93637.1 - 0.12 11.0 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3466) Sugar_tr PF00083.24 KZN93638.1 - 1.3e-96 324.3 25.3 1.5e-96 324.0 25.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN93638.1 - 7.8e-31 107.3 49.9 3.8e-26 91.9 27.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KZN93638.1 - 7.9e-06 24.6 2.2 1.7e-05 23.5 2.2 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KZN93638.1 - 0.00028 20.3 4.4 0.00028 20.3 4.4 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TPR_19 PF14559.6 KZN93638.1 - 0.15 12.6 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Cu_amine_oxid PF01179.20 KZN93641.1 - 1.3e-161 538.2 0.3 1.5e-161 537.9 0.3 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KZN93641.1 - 2.3e-07 31.1 0.0 6.1e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KZN93641.1 - 5.5e-06 26.5 0.1 1.1e-05 25.6 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF5026 PF16429.5 KZN93641.1 - 0.025 14.6 0.0 0.072 13.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5026) HARE-HTH PF05066.13 KZN93642.1 - 0.04 14.3 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain DASH_Spc19 PF08287.11 KZN93642.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Spc19 Isochorismatase PF00857.20 KZN93643.1 - 1e-32 113.7 0.1 1.2e-32 113.5 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family DDE_1 PF03184.19 KZN93644.1 - 1.3e-09 38.0 0.0 2.2e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease TYA PF01021.19 KZN93644.1 - 0.023 15.0 1.3 0.064 13.6 1.3 1.7 1 0 0 1 1 1 0 TYA transposon protein HTH_Tnp_Tc5 PF03221.16 KZN93644.1 - 0.094 12.8 0.0 0.3 11.2 0.0 1.8 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain Acetyltransf_7 PF13508.7 KZN93645.1 - 4.4e-06 27.0 0.0 7.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KZN93645.1 - 1.8e-05 24.7 0.1 2.6e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KZN93645.1 - 6.8e-05 23.1 0.0 9.9e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KZN93645.1 - 0.00083 19.3 0.1 0.0016 18.4 0.1 1.5 1 0 0 1 1 1 1 FR47-like protein GNAT_acetyltran PF12746.7 KZN93645.1 - 0.0009 18.9 0.0 0.0012 18.5 0.0 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_9 PF13527.7 KZN93645.1 - 0.0031 17.6 0.1 0.0052 16.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KZN93645.1 - 0.06 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase WG_beta_rep PF14903.6 KZN93646.1 - 0.035 14.4 0.3 20 5.6 0.0 3.6 4 0 0 4 4 4 0 WG containing repeat Utp14 PF04615.13 KZN93646.1 - 0.067 11.8 6.7 0.094 11.3 6.7 1.1 1 0 0 1 1 1 0 Utp14 protein NAAA-beta PF15508.6 KZN93646.1 - 0.14 12.5 4.4 65 3.9 0.1 6.0 5 1 1 6 6 6 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Het-C PF07217.11 KZN93646.1 - 0.17 10.4 0.9 1.5 7.2 0.1 2.5 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C SOG2 PF10428.9 KZN93646.1 - 0.27 10.4 14.8 0.016 14.4 9.7 1.5 2 0 0 2 2 2 0 RAM signalling pathway protein BLYB PF05289.11 KZN93646.1 - 0.62 10.3 9.8 2.3 8.4 0.3 4.6 3 2 2 5 5 5 0 Borrelia hemolysin accessory protein Ndc1_Nup PF09531.10 KZN93646.1 - 0.71 8.5 3.5 1.3 7.7 3.5 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Nas2_N PF18265.1 KZN93646.1 - 0.93 9.5 2.6 1e+02 2.9 0.0 5.0 6 0 0 6 6 6 0 Nas2 N_terminal domain DUF3206 PF11472.8 KZN93646.1 - 2.3 8.2 5.2 22 5.0 0.2 4.0 3 1 2 5 5 5 0 Protein of unknown function (DUF3206) SWI-SNF_Ssr4 PF08549.10 KZN93646.1 - 3.7 6.1 15.7 5.4 5.5 15.7 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) APH PF01636.23 KZN93647.1 - 7.5e-15 55.5 0.0 1e-14 55.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RNA_pol_I_TF PF04090.12 KZN93647.1 - 0.0082 15.7 0.0 0.015 14.8 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor Choline_kinase PF01633.20 KZN93647.1 - 0.021 14.4 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Zn_clus PF00172.18 KZN93648.1 - 6.2e-08 32.6 11.1 6.2e-08 32.6 11.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN93648.1 - 0.018 14.1 0.4 0.06 12.4 0.4 1.9 1 1 0 1 1 1 0 Fungal specific transcription factor domain Mak10 PF04112.13 KZN93649.1 - 6.1e-64 214.6 0.0 1e-63 213.9 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase ATP-synt_Eps PF04627.13 KZN93650.1 - 1.8e-23 82.2 1.4 1.8e-23 82.2 1.4 1.4 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain GFD1 PF17331.2 KZN93651.1 - 0.055 13.7 3.3 0.17 12.1 3.3 1.8 1 0 0 1 1 1 0 GFD1 mRNA transport factor GP40 PF11025.8 KZN93651.1 - 2.5 7.9 9.2 5.1 6.8 1.5 2.8 2 1 1 3 3 3 0 Glycoprotein GP40 of Cryptosporidium Cpn60_TCP1 PF00118.24 KZN93652.1 - 2.4e-86 290.3 8.4 3.6e-86 289.8 8.4 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HATPase_c PF02518.26 KZN93653.1 - 2.4e-31 108.6 0.1 6.8e-31 107.1 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 KZN93653.1 - 1.4e-29 102.3 17.0 2.2e-08 34.3 0.3 6.8 5 3 2 7 7 7 5 HAMP domain Response_reg PF00072.24 KZN93653.1 - 1.1e-27 96.3 0.1 9.3e-27 93.4 0.3 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KZN93653.1 - 6.2e-15 55.0 1.2 2.8e-14 52.9 0.3 2.8 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain DUF3829 PF12889.7 KZN93653.1 - 0.0078 15.7 1.7 1.3 8.4 0.0 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3829) DUF948 PF06103.11 KZN93653.1 - 0.016 15.4 31.9 0.85 9.9 1.3 7.3 5 2 2 7 7 7 0 Bacterial protein of unknown function (DUF948) Syntaxin_2 PF14523.6 KZN93653.1 - 0.041 14.3 15.1 0.98 9.8 0.0 5.5 5 1 1 6 6 6 0 Syntaxin-like protein HATPase_c_2 PF13581.6 KZN93653.1 - 0.051 13.5 0.1 1.3 9.0 0.0 3.0 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain AdHead_fibreRBD PF16812.5 KZN93653.1 - 0.072 12.9 2.9 0.2 11.5 0.0 2.7 3 0 0 3 3 3 0 C-terminal head domain of the fowl adenovirus type 1 long fibre DUF1843 PF08898.10 KZN93653.1 - 0.37 11.3 9.7 24 5.5 0.0 5.4 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) BORCS6 PF10157.9 KZN93653.1 - 8.3 6.6 9.4 36 4.6 0.0 4.4 3 2 2 5 5 5 0 BLOC-1-related complex sub-unit 6 CorA PF01544.18 KZN93654.1 - 3.1e-10 39.8 0.4 3.1e-10 39.8 0.4 2.2 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF676 PF05057.14 KZN93654.1 - 9e-08 31.9 0.0 2.4e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KZN93654.1 - 0.0015 18.3 0.0 0.0069 16.1 0.0 2.0 2 0 0 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.8 KZN93654.1 - 0.0089 15.3 0.0 0.032 13.5 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_M9_N PF08453.10 KZN93654.1 - 0.025 14.3 0.2 0.048 13.4 0.2 1.4 1 0 0 1 1 1 0 Peptidase family M9 N-terminal Abhydrolase_6 PF12697.7 KZN93654.1 - 0.037 14.6 2.9 0.097 13.3 0.0 2.9 2 2 0 2 2 2 0 Alpha/beta hydrolase family DUF1270 PF06900.11 KZN93654.1 - 0.21 12.0 0.3 0.43 11.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1270) Mito_carr PF00153.27 KZN93655.1 - 3.5e-61 203.1 0.4 1.9e-18 66.1 0.0 4.2 3 1 1 4 4 4 4 Mitochondrial carrier protein Fungal_trans PF04082.18 KZN93656.1 - 5.1e-20 71.6 0.0 2.1e-19 69.6 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 KZN93657.1 - 7.7e-58 195.8 3.7 9.4e-58 195.5 3.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN93657.1 - 1.8e-47 161.3 1.8 2.4e-47 160.9 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN93657.1 - 1.1e-10 41.7 2.3 1.7e-10 41.1 2.3 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KZN93657.1 - 0.0022 17.3 0.3 0.069 12.5 0.0 2.3 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ACT PF01842.25 KZN93657.1 - 0.071 12.9 0.5 0.31 10.9 0.5 2.0 1 1 0 1 1 1 0 ACT domain HATPase_c PF02518.26 KZN93657.1 - 0.14 12.7 0.0 0.54 10.8 0.0 1.8 1 1 1 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sugar_tr PF00083.24 KZN93658.1 - 1.1e-88 298.1 20.8 1.3e-88 297.8 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN93658.1 - 4.1e-27 95.0 42.5 3.4e-26 92.0 23.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TraG-D_C PF12696.7 KZN93658.1 - 0.056 13.4 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG ADH_N PF08240.12 KZN93659.1 - 1.6e-31 108.4 0.2 5.4e-31 106.7 0.2 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN93659.1 - 9.9e-24 83.8 0.0 1.9e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KZN93659.1 - 8.3e-10 38.5 0.0 1.7e-08 34.2 0.0 2.2 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KZN93659.1 - 3.2e-06 28.2 0.0 1.4e-05 26.2 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 KZN93659.1 - 0.0044 16.6 0.1 0.012 15.2 0.1 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Cas_csx3 PF09620.10 KZN93659.1 - 0.052 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) Methyltransf_25 PF13649.6 KZN93659.1 - 0.057 14.1 0.0 0.15 12.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain SopE_GEF PF07487.13 KZN93659.1 - 0.074 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 SopE GEF domain 2-Hacid_dh_C PF02826.19 KZN93659.1 - 0.089 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.12 KZN93659.1 - 0.11 13.1 0.0 0.26 11.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MspA PF09203.11 KZN93660.1 - 0.36 10.7 5.6 13 5.6 3.0 3.2 1 1 1 2 2 2 0 MspA adh_short_C2 PF13561.6 KZN93661.1 - 1e-60 205.2 0.1 1.3e-60 204.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN93661.1 - 5.3e-44 150.0 0.2 6.7e-44 149.7 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN93661.1 - 7.8e-15 55.2 0.6 1.2e-14 54.7 0.6 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KZN93661.1 - 0.00081 18.9 0.1 0.0011 18.5 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 KZN93661.1 - 0.0014 19.0 0.1 0.0028 18.1 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KZN93661.1 - 0.002 17.5 0.6 0.0037 16.6 0.6 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KZN93661.1 - 0.0031 18.1 0.8 0.01 16.4 0.8 1.9 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 KZN93661.1 - 0.019 14.1 0.0 0.027 13.6 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KZN93661.1 - 0.03 14.6 0.2 0.056 13.7 0.2 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 KZN93661.1 - 0.033 14.2 0.1 0.058 13.4 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF2492 PF10678.9 KZN93661.1 - 0.06 13.6 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2492) NAD_binding_2 PF03446.15 KZN93661.1 - 0.067 13.4 0.1 0.39 10.9 0.0 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase YjeF_N PF03853.15 KZN93661.1 - 0.083 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus 3HCDH_N PF02737.18 KZN93661.1 - 0.12 12.2 0.3 0.18 11.7 0.3 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KZN93661.1 - 0.13 11.3 0.5 5.3 6.0 0.1 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 KZN93661.1 - 0.14 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PRK PF00485.18 KZN93662.1 - 0.00068 19.4 0.0 0.00068 19.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family VanY PF02557.17 KZN93662.1 - 0.12 12.2 0.0 1.1 9.1 0.0 1.9 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase F-box-like PF12937.7 KZN93663.1 - 1.2e-06 28.4 0.0 2.7e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN93663.1 - 0.012 15.5 0.0 0.031 14.1 0.0 1.7 1 0 0 1 1 1 0 F-box domain MIT PF04212.18 KZN93663.1 - 0.067 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 KZN93663.1 - 0.19 11.9 0.2 1.3 9.3 0.2 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat NAD_binding_10 PF13460.6 KZN93664.1 - 1.3e-07 31.7 0.1 6e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KZN93664.1 - 1.9e-07 30.8 0.0 4.5e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KZN93664.1 - 3.6e-06 26.7 0.0 5.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KZN93664.1 - 0.00019 21.7 0.1 0.00063 20.0 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 KZN93664.1 - 0.0076 15.3 0.0 0.02 13.9 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KZN93664.1 - 0.0096 15.1 0.0 0.022 13.9 0.0 1.6 1 1 1 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.24 KZN93664.1 - 0.024 15.1 0.0 0.052 14.0 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CMAS PF02353.20 KZN93665.1 - 3.9e-45 154.3 0.1 4.7e-45 154.0 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KZN93665.1 - 6.9e-13 48.8 0.0 1e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN93665.1 - 3.1e-11 43.9 0.0 6.1e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN93665.1 - 5.4e-10 39.8 0.0 1.2e-09 38.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN93665.1 - 1.1e-09 38.8 0.0 2.7e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KZN93665.1 - 0.0015 18.1 0.0 0.0033 17.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 KZN93665.1 - 0.0068 15.8 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.19 KZN93665.1 - 0.0094 15.7 0.0 0.031 14.0 0.0 1.8 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KZN93665.1 - 0.0098 15.7 0.0 0.02 14.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KZN93665.1 - 0.025 13.9 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain RSN1_TM PF13967.6 KZN93665.1 - 0.051 13.3 0.1 0.084 12.6 0.1 1.2 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport B3_4 PF03483.17 KZN93667.1 - 8.4e-22 77.7 0.0 1.1e-21 77.3 0.0 1.1 1 0 0 1 1 1 1 B3/4 domain UCR_14kD PF02271.16 KZN93667.1 - 0.085 12.8 0.2 0.21 11.6 0.2 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Glyco_hydro_32C PF08244.12 KZN93668.1 - 1.9e-25 89.7 2.0 4.5e-25 88.5 2.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.20 KZN93668.1 - 3.6e-13 49.7 0.0 5.5e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain HA2 PF04408.23 KZN93669.1 - 9.2e-22 77.4 3.2 1.9e-21 76.4 0.1 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KZN93669.1 - 1.3e-13 51.1 0.0 2.9e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KZN93669.1 - 9.1e-12 45.3 0.0 3e-11 43.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KZN93669.1 - 4.3e-05 23.3 0.0 9.8e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KZN93669.1 - 0.00086 19.6 0.0 0.0031 17.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KZN93669.1 - 0.011 15.3 0.0 0.032 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KZN93669.1 - 0.014 15.2 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KZN93669.1 - 0.028 14.1 0.0 0.11 12.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KZN93669.1 - 0.031 14.6 0.0 0.13 12.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KZN93669.1 - 0.036 13.6 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 KZN93669.1 - 0.051 12.6 0.0 0.096 11.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 KZN93669.1 - 0.13 11.6 0.0 0.46 9.8 0.0 1.8 2 0 0 2 2 2 0 KaiC Zn_clus PF00172.18 KZN93671.1 - 2.3e-08 34.0 10.3 4.2e-08 33.2 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KZN93671.1 - 1.5e-05 24.2 0.7 7.7e-05 21.8 0.5 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KZN93672.1 - 2.7e-43 148.2 43.8 2.7e-43 148.2 43.8 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KZN93672.1 - 3.7e-07 28.9 18.4 5.1e-07 28.5 18.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FAD_binding_3 PF01494.19 KZN93673.1 - 1.9e-14 53.7 0.1 8.2e-14 51.6 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KZN93673.1 - 7.5e-10 38.9 2.9 0.0024 17.5 0.0 3.3 1 1 2 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KZN93673.1 - 9e-05 21.8 0.0 0.056 12.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KZN93673.1 - 0.00023 20.4 0.3 0.00049 19.3 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KZN93673.1 - 0.0044 15.8 0.2 0.16 10.6 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KZN93673.1 - 0.0076 15.5 0.0 0.14 11.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN93673.1 - 0.018 15.3 0.2 0.046 13.9 0.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KZN93673.1 - 0.047 12.9 0.1 6.3 6.0 0.0 2.2 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.7 KZN93673.1 - 0.056 12.8 0.5 0.13 11.6 0.5 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KZN93673.1 - 0.064 12.3 2.2 0.17 10.9 0.2 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 KZN93673.1 - 0.08 12.0 0.4 0.34 10.0 0.2 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 KZN93673.1 - 0.084 11.7 0.6 7.8 5.2 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase adh_short PF00106.25 KZN93674.1 - 3.3e-25 88.7 0.1 4.6e-25 88.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN93674.1 - 2.7e-20 73.0 0.1 3.2e-20 72.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN93674.1 - 2.8e-07 30.6 0.0 5.2e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KZN93674.1 - 4.4e-07 29.6 0.1 3.3e-06 26.7 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KZN93674.1 - 8.6e-06 25.4 0.2 0.00012 21.6 0.2 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KZN93674.1 - 0.06 12.5 0.2 0.49 9.5 0.2 2.1 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KZN93674.1 - 0.069 13.0 0.1 0.11 12.4 0.1 1.6 1 1 0 1 1 1 0 NAD(P)H-binding p450 PF00067.22 KZN93675.1 - 9.4e-30 103.7 0.0 1.4e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 KZN93676.1 - 1.1e-34 119.6 0.5 1.3e-34 119.3 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN93676.1 - 2.7e-22 79.5 0.4 7.1e-22 78.1 0.4 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN93676.1 - 1.9e-10 40.9 0.1 2.7e-10 40.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KZN93676.1 - 1.4e-09 37.6 0.1 1.7e-09 37.2 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KZN93676.1 - 4.5e-08 32.9 0.2 8.4e-08 32.0 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KZN93676.1 - 0.00099 18.3 0.2 0.0015 17.7 0.2 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain LDcluster4 PF18306.1 KZN93676.1 - 0.035 13.7 0.2 0.27 10.8 0.1 2.0 2 0 0 2 2 2 0 SLOG cluster4 family Eno-Rase_NADH_b PF12242.8 KZN93676.1 - 0.078 12.8 1.0 0.15 11.8 0.1 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3Beta_HSD PF01073.19 KZN93676.1 - 0.082 11.9 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Questin_oxidase PF14027.6 KZN93677.1 - 1.3e-93 314.3 0.3 1.5e-93 314.0 0.3 1.1 1 0 0 1 1 1 1 Questin oxidase-like NAD_binding_10 PF13460.6 KZN93678.1 - 3e-17 63.1 0.0 3.8e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KZN93678.1 - 3.2e-06 26.9 0.0 1.3e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 KZN93678.1 - 0.0039 16.2 0.2 0.0063 15.5 0.1 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KZN93678.1 - 0.081 12.1 0.0 0.17 11.0 0.0 1.6 1 1 0 1 1 1 0 Male sterility protein Semialdhyde_dh PF01118.24 KZN93678.1 - 0.15 12.5 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KZN93678.1 - 0.2 10.7 0.0 0.41 9.7 0.0 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein HSP20 PF00011.21 KZN93679.1 - 1.9e-13 50.4 0.2 2.6e-13 50.0 0.2 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KZN93679.1 - 0.00058 19.4 0.2 0.003 17.1 0.1 2.1 1 1 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 KZN93679.1 - 0.1 13.6 0.0 0.27 12.3 0.0 1.6 1 0 0 1 1 1 0 CS domain Scytalone_dh PF02982.14 KZN93680.1 - 3.4e-72 241.5 1.1 3.8e-72 241.3 1.1 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 KZN93680.1 - 2.5e-07 30.9 0.4 3.2e-07 30.5 0.4 1.1 1 0 0 1 1 1 1 SnoaL-like domain HNOB PF07700.15 KZN93680.1 - 0.15 12.0 0.0 5.6 6.9 0.0 2.1 2 0 0 2 2 2 0 Haem-NO-binding ketoacyl-synt PF00109.26 KZN93681.1 - 8.4e-72 241.8 0.0 1.6e-71 240.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KZN93681.1 - 2.1e-43 149.0 0.0 4.1e-43 148.1 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KZN93681.1 - 8.5e-33 112.9 1.2 1.9e-32 111.8 1.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KZN93681.1 - 2.7e-11 43.3 0.0 4.9e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 KZN93681.1 - 8.2e-10 38.9 0.2 2.3e-09 37.5 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KZN93681.1 - 2.2e-06 28.1 0.0 5.2e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KZN93681.1 - 0.00015 21.2 0.2 0.00057 19.3 0.1 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Glyco_transf_28 PF03033.20 KZN93683.1 - 1.4e-12 47.9 0.0 6e-12 45.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KZN93683.1 - 1.9e-06 26.9 0.0 3.1e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 KZN93683.1 - 0.00074 19.8 0.1 0.13 12.6 0.0 3.1 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 KZN93683.1 - 0.0045 17.0 0.0 0.0083 16.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DUF2985 PF11204.8 KZN93684.1 - 1.4e-31 108.5 3.6 1.4e-31 108.5 3.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) MerC PF03203.14 KZN93684.1 - 0.056 13.9 2.5 0.15 12.5 0.1 2.3 2 0 0 2 2 2 0 MerC mercury resistance protein Glyco_hydro_5_C PF18564.1 KZN93685.1 - 1.6e-20 73.4 0.0 4.3e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KZN93685.1 - 1.1e-08 34.8 2.1 8.2e-08 32.0 1.4 2.5 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) FMO-like PF00743.19 KZN93686.1 - 3e-10 39.2 0.0 1.3e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KZN93686.1 - 1.6e-08 34.7 0.4 9.9e-06 25.7 0.0 3.4 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KZN93686.1 - 6.9e-07 28.8 0.0 0.00014 21.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KZN93686.1 - 9.5e-07 28.3 0.0 3.2e-05 23.2 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KZN93686.1 - 9.4e-06 25.0 0.0 0.0056 15.9 0.0 2.8 3 0 0 3 3 3 2 Thi4 family DAO PF01266.24 KZN93686.1 - 1.1e-05 25.2 0.1 0.0047 16.6 0.0 3.1 3 1 1 4 4 4 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KZN93686.1 - 8.1e-05 22.7 0.0 0.0031 17.6 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KZN93686.1 - 0.00016 21.7 0.4 0.072 13.1 0.0 3.3 3 1 0 3 3 3 1 FAD-NAD(P)-binding Semialdhyde_dh PF01118.24 KZN93686.1 - 0.003 18.0 0.0 0.042 14.3 0.0 2.5 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KZN93686.1 - 0.0078 15.6 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KZN93686.1 - 0.099 11.7 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Methyltransf_13 PF08421.11 KZN93686.1 - 0.21 11.9 0.3 0.67 10.3 0.2 1.8 2 0 0 2 2 2 0 Putative zinc binding domain Dyp_perox PF04261.12 KZN93687.1 - 4e-86 289.0 0.0 4.7e-86 288.8 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family adh_short_C2 PF13561.6 KZN93688.1 - 5.8e-60 202.8 1.8 7.8e-60 202.3 1.8 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN93688.1 - 2.9e-48 163.9 0.8 4.9e-48 163.2 0.8 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN93688.1 - 2.3e-13 50.5 2.7 4.4e-12 46.3 2.7 2.1 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KZN93688.1 - 5.7e-08 32.2 0.3 1.2e-07 31.2 0.1 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Ldh_1_N PF00056.23 KZN93688.1 - 0.046 13.8 0.1 0.12 12.5 0.1 1.7 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Adeno_PIX PF03955.14 KZN93688.1 - 0.1 12.8 0.1 0.1 12.8 0.1 1.7 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Fungal_trans_2 PF11951.8 KZN93689.1 - 7.1e-56 189.7 1.3 8.7e-56 189.4 1.3 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 KZN93690.1 - 4.9e-61 206.3 1.3 5.5e-61 206.1 1.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN93690.1 - 5e-47 159.9 0.5 6.7e-47 159.5 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN93690.1 - 1.7e-09 37.9 0.5 2.6e-09 37.3 0.5 1.2 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 KZN93690.1 - 0.00021 21.3 0.5 0.0016 18.5 0.5 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 3HCDH_N PF02737.18 KZN93690.1 - 0.00053 19.9 0.3 0.0011 18.9 0.1 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ank_2 PF12796.7 KZN93691.1 - 9e-19 67.9 0.1 4.7e-13 49.5 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN93691.1 - 4e-18 65.5 0.0 5.9e-07 29.9 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN93691.1 - 6.4e-17 59.9 1.1 3.4e-07 30.1 0.1 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 KZN93691.1 - 4.6e-15 55.3 5.1 2.2e-09 37.4 0.2 4.5 5 0 0 5 5 4 2 Ankyrin repeat Ank_5 PF13857.6 KZN93691.1 - 1.2e-14 54.2 0.7 3.8e-07 30.3 0.1 4.4 2 2 2 4 4 4 3 Ankyrin repeats (many copies) AAA_16 PF13191.6 KZN93691.1 - 4.8e-08 33.6 2.7 4.2e-07 30.5 0.0 3.4 4 0 0 4 4 4 1 AAA ATPase domain NACHT PF05729.12 KZN93691.1 - 1.7e-07 31.3 0.0 3.7e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KZN93691.1 - 4.3e-05 23.8 0.5 0.00045 20.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 KZN93691.1 - 0.0042 16.4 0.1 0.13 11.5 0.0 2.4 1 1 1 2 2 2 1 KAP family P-loop domain NB-ARC PF00931.22 KZN93691.1 - 0.066 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 KZN93691.1 - 0.12 12.3 0.0 0.47 10.3 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Clat_adaptor_s PF01217.20 KZN93692.1 - 8.6e-11 41.9 0.0 2.6e-10 40.4 0.1 1.6 2 0 0 2 2 2 1 Clathrin adaptor complex small chain DUF948 PF06103.11 KZN93693.1 - 1.3 9.3 3.8 0.4 11.0 0.6 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TTKRSYEDQ PF10212.9 KZN93693.1 - 2.4 7.1 15.7 0.071 12.1 6.3 2.3 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein FapA PF03961.13 KZN93693.1 - 7 5.1 15.3 4.6 5.7 12.9 1.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A PQ-loop PF04193.14 KZN93695.1 - 1.9e-18 66.0 2.1 1.9e-18 66.0 2.1 2.5 4 0 0 4 4 4 1 PQ loop repeat CYSTM PF12734.7 KZN93695.1 - 0.0017 18.6 0.1 0.019 15.3 0.0 2.2 2 0 0 2 2 2 1 Cysteine-rich TM module stress tolerance Ribosomal_L16 PF00252.18 KZN93696.1 - 4.1e-45 153.0 0.1 5.1e-45 152.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e CFEM PF05730.11 KZN93697.1 - 6.1e-05 23.0 1.0 7.4e-05 22.8 1.0 1.1 1 0 0 1 1 1 1 CFEM domain EGF PF00008.27 KZN93697.1 - 0.022 15.1 0.4 0.06 13.7 0.2 1.8 2 0 0 2 2 2 0 EGF-like domain NFACT-C PF11923.8 KZN93698.1 - 1.2e-40 137.7 0.2 1.2e-40 137.7 0.2 3.9 5 0 0 5 5 5 1 NFACT protein C-terminal domain FbpA PF05833.11 KZN93698.1 - 2.4e-33 115.6 15.4 2.4e-33 115.6 15.4 2.6 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 KZN93698.1 - 5.7e-27 94.5 0.0 1.3e-26 93.4 0.0 1.6 1 0 0 1 1 1 1 NFACT protein RNA binding domain Sua5_yciO_yrdC PF01300.18 KZN93699.1 - 1.5e-56 190.7 0.0 2.4e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 KZN93699.1 - 1e-31 110.3 0.0 2.1e-31 109.2 0.0 1.5 2 0 0 2 2 2 1 Putative GTP-binding controlling metal-binding A_deaminase PF00962.22 KZN93700.1 - 1.3e-79 267.9 0.0 1.5e-79 267.7 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 KZN93700.1 - 0.034 13.5 0.0 0.26 10.6 0.0 2.2 1 1 0 1 1 1 0 Amidohydrolase family 2Fe-2S_thioredx PF01257.19 KZN93702.1 - 5.3e-60 201.5 0.1 6.6e-60 201.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin SNF2_N PF00176.23 KZN93703.1 - 8.2e-20 70.8 0.0 1.4e-14 53.6 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 KZN93703.1 - 2.3e-13 50.2 0.0 6.6e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.31 KZN93703.1 - 0.0067 16.8 0.0 0.017 15.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KZN93703.1 - 0.052 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CSTF2_hinge PF14327.6 KZN93704.1 - 4.2e-31 107.2 2.4 4.2e-31 107.2 2.4 2.4 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KZN93704.1 - 3e-19 68.6 0.0 4.7e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KZN93704.1 - 1e-17 63.4 10.0 1e-17 63.4 10.0 3.4 4 0 0 4 4 4 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 KZN93704.1 - 0.0099 16.0 0.1 0.81 9.8 0.0 2.5 1 1 1 2 2 2 1 RNA recognition motif Spo7_2_N PF15407.6 KZN93704.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein family 7 RRM_5 PF13893.6 KZN93704.1 - 0.053 13.1 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KZN93704.1 - 0.066 13.1 0.0 0.2 11.5 0.0 1.8 1 1 0 1 1 1 0 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 KZN93704.1 - 0.099 12.4 0.0 4 7.2 0.0 2.2 1 1 1 2 2 2 0 Rrp7 RRM-like N-terminal domain Band_7 PF01145.25 KZN93705.1 - 3.4e-24 85.8 3.5 5.2e-24 85.2 3.5 1.3 1 1 0 1 1 1 1 SPFH domain / Band 7 family Sporozoite_P67 PF05642.11 KZN93706.1 - 0.03 12.4 0.1 0.044 11.9 0.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ank_4 PF13637.6 KZN93706.1 - 0.14 12.8 0.0 15 6.3 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 KZN93706.1 - 0.18 12.3 0.0 0.73 10.4 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeat RSN1_7TM PF02714.15 KZN93707.1 - 9.5e-88 294.1 29.5 9.5e-88 294.1 29.5 1.9 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KZN93707.1 - 2.7e-48 163.7 0.4 2.7e-48 163.7 0.4 3.2 2 1 1 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KZN93707.1 - 2e-30 106.4 2.9 7.1e-18 65.4 0.1 2.8 3 0 0 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KZN93707.1 - 2.4e-13 50.0 0.4 6.5e-13 48.7 0.0 1.9 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter Herpes_UL25 PF01499.16 KZN93707.1 - 0.032 12.8 0.0 0.048 12.2 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family R3H PF01424.22 KZN93707.1 - 1.8 8.6 4.6 0.36 10.8 0.5 1.9 2 0 0 2 2 2 0 R3H domain TAF4 PF05236.14 KZN93707.1 - 2.2 7.9 10.6 0.86 9.3 4.0 2.2 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family MCM PF00493.23 KZN93708.1 - 8.5e-102 339.0 0.0 1.2e-101 338.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KZN93708.1 - 2.8e-39 133.8 0.6 6.7e-39 132.6 0.6 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KZN93708.1 - 5.6e-29 100.4 0.6 1.1e-28 99.4 0.6 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KZN93708.1 - 3.9e-14 53.1 0.1 1.4e-13 51.3 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KZN93708.1 - 6.7e-06 25.6 0.0 0.00018 21.0 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KZN93708.1 - 1.2e-05 25.3 0.0 3.3e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KZN93708.1 - 0.002 18.0 0.0 0.0063 16.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KZN93708.1 - 0.17 11.6 0.1 6.2 6.5 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain VTC PF09359.10 KZN93709.1 - 1.4e-100 336.2 0.4 2.5e-100 335.4 0.4 1.4 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 KZN93709.1 - 2.4e-12 47.1 5.6 2.4e-12 47.1 5.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 KZN93709.1 - 3.8e-11 43.6 18.2 1.4e-05 25.2 0.5 3.8 2 1 1 4 4 4 3 SPX domain DED PF01335.21 KZN93709.1 - 0.1 12.9 0.0 0.35 11.2 0.0 1.9 1 0 0 1 1 1 0 Death effector domain Oxidored_q6 PF01058.22 KZN93711.1 - 7.7e-23 80.8 0.0 8.9e-23 80.6 0.0 1.0 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit DEC-1_C PF04626.13 KZN93711.1 - 0.064 13.7 0.4 0.082 13.3 0.4 1.2 1 0 0 1 1 1 0 Dec-1 protein, C terminal region DEAD PF00270.29 KZN93712.1 - 6.4e-17 61.9 0.0 1.8e-16 60.4 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KZN93712.1 - 1.3e-08 35.0 0.0 2.2e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KZN93712.1 - 1.4e-07 31.8 0.0 4.4e-07 30.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4332 PF14229.6 KZN93712.1 - 0.014 15.6 0.1 0.053 13.8 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) AAA_22 PF13401.6 KZN93712.1 - 0.016 15.5 0.1 0.14 12.4 0.1 2.5 1 1 0 1 1 1 0 AAA domain Sigma70_r4 PF04545.16 KZN93712.1 - 0.041 13.4 0.0 0.21 11.1 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 zf-HC5HC2H_2 PF13832.6 KZN93713.1 - 6.4e-22 77.8 0.2 6.4e-22 77.8 0.2 4.4 5 0 0 5 5 5 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KZN93713.1 - 2.5e-20 72.5 0.8 2.5e-20 72.5 0.8 4.3 4 1 0 4 4 4 1 PHD-like zinc-binding domain BAH PF01426.18 KZN93713.1 - 2.3e-15 56.5 0.0 4.9e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 BAH domain PHD_2 PF13831.6 KZN93713.1 - 4.5e-09 35.7 4.1 4.5e-09 35.7 4.1 4.7 5 0 0 5 5 5 2 PHD-finger PHD PF00628.29 KZN93713.1 - 5.7e-09 35.7 25.3 7.5e-07 28.9 7.4 5.1 6 0 0 6 6 6 2 PHD-finger Myb_DNA-binding PF00249.31 KZN93713.1 - 1.7e-05 24.9 0.1 7.7e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain C1_2 PF03107.16 KZN93713.1 - 0.033 14.5 0.7 0.033 14.5 0.7 5.9 6 0 0 6 6 6 0 C1 domain ArfGap PF01412.18 KZN93713.1 - 0.36 10.9 6.2 12 6.0 0.0 3.9 4 0 0 4 4 4 0 Putative GTPase activating protein for Arf ELM2 PF01448.24 KZN93713.1 - 2.4 9.0 7.2 4.1 8.2 1.8 3.6 3 1 0 3 3 3 0 ELM2 domain ADH_zinc_N PF00107.26 KZN93714.1 - 1.2e-24 86.8 0.1 1.9e-24 86.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KZN93714.1 - 3.2e-18 67.1 0.0 5.4e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KZN93714.1 - 2.2e-08 33.9 0.0 5.5e-07 29.4 0.0 2.2 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain PDEase_I PF00233.19 KZN93715.1 - 3.3e-70 236.5 0.0 5.8e-70 235.7 0.0 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Actino_peptide PF14408.6 KZN93715.1 - 0.14 12.3 2.5 0.79 9.9 2.5 2.3 1 0 0 1 1 1 0 Ribosomally synthesised peptide in actinomycetes Rdx PF10262.9 KZN93716.1 - 7.3e-32 109.4 0.0 1.1e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Rdx family G-gamma PF00631.22 KZN93717.1 - 1.2e-23 82.9 0.0 1.4e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 GGL domain PCI PF01399.27 KZN93718.1 - 2.9e-09 37.4 0.0 2.9e-09 37.4 0.0 3.1 3 0 0 3 3 3 1 PCI domain Acetyltransf_1 PF00583.25 KZN93720.1 - 1.1e-08 35.3 0.0 1.4e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KZN93720.1 - 1.3e-06 28.4 0.0 1.9e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KZN93720.1 - 2.2e-06 27.6 0.0 3.2e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KZN93720.1 - 3.6e-05 24.1 0.0 4.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KZN93720.1 - 0.012 15.6 0.2 0.026 14.6 0.2 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 KZN93721.1 - 8.3e-21 74.3 50.5 4.9e-14 52.0 34.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4808 PF16066.5 KZN93721.1 - 0.055 14.0 0.1 0.1 13.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4808) 7tm_1 PF00001.21 KZN93721.1 - 0.057 12.7 1.6 0.36 10.1 0.0 2.8 3 0 0 3 3 3 0 7 transmembrane receptor (rhodopsin family) RNA_pol_Rpb6 PF01192.22 KZN93722.1 - 6e-17 61.3 0.1 9.6e-17 60.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 zf-C2H2 PF00096.26 KZN93723.1 - 4.7e-32 108.6 59.8 9.3e-05 22.7 1.2 10.8 11 0 0 11 11 11 10 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KZN93723.1 - 2.8e-19 68.6 53.2 1.4e-06 28.5 0.2 10.5 11 0 0 11 11 11 7 Zinc-finger double domain zf-C2H2_4 PF13894.6 KZN93723.1 - 3.5e-19 67.8 53.5 0.02 15.7 2.4 10.7 11 0 0 11 11 10 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KZN93723.1 - 1.2e-09 38.2 14.7 0.17 12.2 2.0 8.3 9 0 0 9 9 9 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KZN93723.1 - 8.8e-05 22.7 25.2 0.14 12.5 1.5 5.7 3 3 2 5 5 5 3 C2H2-type zinc ribbon FOXP-CC PF16159.5 KZN93723.1 - 0.0005 20.6 33.3 2 9.1 0.0 8.7 7 1 2 9 9 9 3 FOXP coiled-coil domain zf-met PF12874.7 KZN93723.1 - 0.0013 19.0 12.4 3.9 8.0 0.1 6.5 7 0 0 7 7 7 1 Zinc-finger of C2H2 type GAGA PF09237.11 KZN93723.1 - 0.0058 16.4 8.4 0.013 15.3 1.3 3.6 3 0 0 3 3 3 1 GAGA factor zf-C2H2_3rep PF18868.1 KZN93723.1 - 0.045 14.4 24.6 1.3 9.7 4.1 5.3 2 2 3 5 5 5 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_aberr PF17017.5 KZN93723.1 - 0.049 13.8 16.1 1.8 8.7 0.1 4.7 3 1 2 5 5 5 0 Aberrant zinc-finger zf-C2H2_6 PF13912.6 KZN93723.1 - 0.23 11.5 0.0 0.23 11.5 0.0 7.8 9 0 0 9 9 9 0 C2H2-type zinc finger Ribosomal_L37e PF01907.19 KZN93723.1 - 0.43 10.8 4.4 0.2 11.8 0.5 2.5 2 0 0 2 2 2 0 Ribosomal protein L37e PH PF00169.29 KZN93725.1 - 7.4e-06 26.4 0.0 0.00016 22.2 0.0 2.5 2 0 0 2 2 2 1 PH domain ADH_N PF08240.12 KZN93726.1 - 1.6e-06 28.0 0.0 3.2e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN93726.1 - 0.0035 17.3 0.1 0.024 14.6 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Fungal_trans PF04082.18 KZN93727.1 - 0.00071 18.7 0.3 0.00097 18.2 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC_membrane PF00664.23 KZN93728.1 - 5e-94 315.0 37.3 3.9e-50 171.0 20.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KZN93728.1 - 1.7e-67 226.2 0.0 2.9e-32 112.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KZN93728.1 - 1.4e-10 40.9 10.6 0.001 18.5 0.0 5.1 4 2 0 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KZN93728.1 - 9.4e-10 39.1 0.9 0.00011 22.6 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KZN93728.1 - 5.8e-08 33.1 1.5 0.015 15.5 0.1 3.8 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KZN93728.1 - 9.8e-08 31.6 0.2 0.00064 19.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KZN93728.1 - 4.4e-07 30.0 0.0 0.039 13.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 KZN93728.1 - 3.6e-06 26.0 0.2 0.014 14.3 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_30 PF13604.6 KZN93728.1 - 7.3e-06 25.8 1.6 0.23 11.2 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.6 KZN93728.1 - 1.3e-05 25.1 0.1 0.0042 16.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 KZN93728.1 - 2.5e-05 24.9 4.7 0.053 14.0 0.2 3.4 4 0 0 4 4 3 2 AAA domain ATP-synt_ab PF00006.25 KZN93728.1 - 7.2e-05 22.5 0.0 0.19 11.3 0.0 3.3 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 KZN93728.1 - 0.00031 20.3 0.6 0.7 9.4 0.0 2.9 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA PF00004.29 KZN93728.1 - 0.00091 19.7 1.6 2.8 8.4 0.5 4.3 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KZN93728.1 - 0.00093 19.2 0.0 2.7 8.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KZN93728.1 - 0.001 18.7 0.1 2.5 7.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 KZN93728.1 - 0.0022 17.8 4.4 2.1 8.1 0.1 3.7 3 1 0 4 4 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 KZN93728.1 - 0.0023 18.2 0.2 0.17 12.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KZN93728.1 - 0.0032 17.7 1.6 1.8 8.8 0.1 3.9 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KZN93728.1 - 0.0033 17.6 0.0 3.4 7.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KZN93728.1 - 0.0048 16.1 0.3 1 8.5 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain G-alpha PF00503.20 KZN93728.1 - 0.0053 16.0 0.0 0.61 9.2 0.0 2.4 2 0 0 2 2 2 1 G-protein alpha subunit IstB_IS21 PF01695.17 KZN93728.1 - 0.0069 16.1 0.1 2.3 7.9 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 KZN93728.1 - 0.0088 15.3 0.7 1.6 7.9 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin AAA_24 PF13479.6 KZN93728.1 - 0.012 15.4 0.0 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KZN93728.1 - 0.019 14.9 0.0 3.4 7.5 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain Mg_chelatase PF01078.21 KZN93728.1 - 0.024 14.0 0.0 0.51 9.7 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KZN93728.1 - 0.027 15.0 0.0 7.3 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KZN93728.1 - 0.031 14.3 0.0 9.1 6.3 0.0 3.4 4 0 0 4 4 3 0 AAA domain Synapsin_N PF10581.9 KZN93728.1 - 0.035 14.1 0.0 0.21 11.6 0.0 2.2 2 0 0 2 2 2 0 Synapsin N-terminal SRP54 PF00448.22 KZN93728.1 - 0.047 13.3 0.0 2.8 7.5 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 KZN93728.1 - 0.062 13.4 0.1 16 5.6 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 KZN93728.1 - 0.074 13.4 0.0 14 6.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase PRK PF00485.18 KZN93728.1 - 0.12 12.1 0.2 6.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 KZN93728.1 - 0.22 11.4 0.7 27 4.6 0.0 3.0 3 0 0 3 3 2 0 NACHT domain Sugar_tr PF00083.24 KZN93729.1 - 1.7e-89 300.8 28.6 2e-89 300.6 28.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN93729.1 - 2.6e-19 69.4 49.3 2e-13 50.0 18.6 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Neurensin PF14927.6 KZN93729.1 - 1.1 8.9 5.6 0.67 9.7 0.1 3.0 4 0 0 4 4 4 0 Neurensin TssN PF17555.2 KZN93729.1 - 5.6 6.3 7.8 3 7.2 1.5 2.5 2 1 0 2 2 2 0 Type VI secretion system, TssN ADH_N PF08240.12 KZN93730.1 - 8.8e-34 115.7 0.1 1.5e-33 114.9 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN93730.1 - 7.7e-27 93.8 0.4 1.1e-26 93.3 0.4 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KZN93730.1 - 8.4e-10 38.5 0.3 1.3e-09 37.9 0.3 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KZN93730.1 - 8.3e-06 26.9 0.0 1.5e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KZN93730.1 - 5.1e-05 22.7 0.6 0.0001 21.7 0.6 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KZN93730.1 - 0.0056 16.9 0.0 0.012 15.9 0.0 1.7 1 1 0 1 1 1 1 TrkA-N domain Pyr_redox_2 PF07992.14 KZN93730.1 - 0.0064 15.8 0.1 0.035 13.3 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_25 PF13649.6 KZN93730.1 - 0.015 16.0 0.1 0.046 14.4 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 KZN93730.1 - 0.018 14.6 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PALP PF00291.25 KZN93730.1 - 0.024 14.1 1.1 0.036 13.5 1.1 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Methyltransf_11 PF08241.12 KZN93730.1 - 0.12 13.0 0.0 0.28 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 KZN93730.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FGGY_C PF02782.16 KZN93731.1 - 1.3e-48 165.4 0.1 1.9e-48 164.8 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KZN93731.1 - 3.8e-22 79.1 0.0 2.7e-20 73.0 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KZN93731.1 - 0.042 13.3 0.0 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Hexokinase_1 PF00349.21 KZN93731.1 - 0.18 11.7 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 Hexokinase Fungal_trans PF04082.18 KZN93732.1 - 0.022 13.8 0.1 0.22 10.5 0.1 2.2 1 1 0 1 1 1 0 Fungal specific transcription factor domain MtrB PF05440.12 KZN93732.1 - 0.11 12.9 0.1 0.25 11.8 0.1 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B GST_C PF00043.25 KZN93733.1 - 4.8e-17 62.0 0.0 7.4e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KZN93733.1 - 2.7e-15 56.5 0.0 4.6e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KZN93733.1 - 1.3e-13 51.1 0.0 2.4e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KZN93733.1 - 1.9e-12 47.2 0.0 3.2e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KZN93733.1 - 9.2e-09 35.5 0.0 2.1e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KZN93733.1 - 4.2e-05 23.5 0.0 7.8e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KZN93733.1 - 0.094 13.3 0.0 0.19 12.3 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Plant_NMP1 PF06694.11 KZN93733.1 - 0.21 10.7 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) MFS_1 PF07690.16 KZN93734.1 - 1.9e-29 102.7 30.0 1.1e-27 96.9 29.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KZN93734.1 - 0.0026 16.3 1.8 0.0026 16.3 1.8 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) COPIIcoated_ERV PF07970.12 KZN93735.1 - 1.3e-83 280.2 0.0 2.9e-83 279.1 0.0 1.5 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KZN93735.1 - 5.5e-30 103.6 0.0 1.1e-29 102.5 0.0 1.6 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) TAP_C PF03943.13 KZN93736.1 - 8.8e-17 60.5 1.0 1.7e-16 59.5 1.0 1.5 1 0 0 1 1 1 1 TAP C-terminal domain NTF2 PF02136.20 KZN93736.1 - 6.6e-08 33.1 0.0 1.4e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_4 PF12799.7 KZN93736.1 - 0.00015 22.0 1.8 0.0029 18.0 0.2 2.5 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KZN93736.1 - 0.0036 16.8 0.1 0.0098 15.4 0.0 1.7 1 1 1 2 2 2 1 Leucine-rich repeat RRM_9 PF18444.1 KZN93736.1 - 0.014 15.2 0.0 0.035 14.0 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif LRR_8 PF13855.6 KZN93736.1 - 0.016 15.0 1.5 0.092 12.5 1.2 2.4 1 1 1 2 2 2 0 Leucine rich repeat DEC-1_N PF04625.13 KZN93736.1 - 1.7 7.6 9.5 1.4 7.8 7.4 1.8 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Vps53_N PF04100.12 KZN93737.1 - 5.4e-109 364.6 4.2 6e-109 364.5 2.8 1.7 2 0 0 2 2 2 1 Vps53-like, N-terminal Vps54_N PF10475.9 KZN93737.1 - 9.7e-06 25.1 6.2 2.3e-05 23.9 6.2 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KZN93737.1 - 2.2e-05 24.4 0.7 7.8e-05 22.6 0.7 2.0 1 1 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) RINT1_TIP1 PF04437.13 KZN93737.1 - 0.00015 20.8 1.7 0.00015 20.8 1.7 3.0 2 1 0 2 2 2 1 RINT-1 / TIP-1 family COG2 PF06148.11 KZN93737.1 - 0.0089 16.1 3.6 0.0089 16.1 3.6 2.6 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 KZN93737.1 - 0.028 13.3 5.2 0.061 12.2 5.2 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 KZN93737.1 - 0.064 13.8 7.0 0.16 12.5 6.3 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region Sigma70_ner PF04546.13 KZN93737.1 - 0.11 12.4 7.4 0.049 13.5 4.7 1.9 2 0 0 2 2 1 0 Sigma-70, non-essential region FtsK_SpoIIIE PF01580.18 KZN93737.1 - 0.13 11.6 0.9 0.28 10.5 0.6 1.6 1 1 0 1 1 1 0 FtsK/SpoIIIE family Sec8_exocyst PF04048.14 KZN93737.1 - 0.22 11.4 3.6 0.27 11.1 1.6 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain BRE1 PF08647.11 KZN93737.1 - 0.6 10.2 5.5 2.1 8.5 5.5 2.0 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF1515 PF07439.11 KZN93737.1 - 0.79 9.8 3.1 1.1 9.3 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Baculo_PEP_C PF04513.12 KZN93737.1 - 1.1 9.3 7.6 2 8.4 6.0 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus XhlA PF10779.9 KZN93737.1 - 3.8 7.8 5.6 1.9 8.8 2.6 2.1 2 0 0 2 2 1 0 Haemolysin XhlA Fungal_trans PF04082.18 KZN93739.1 - 6.4e-19 68.0 0.2 1.2e-18 67.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN93739.1 - 9.5e-10 38.4 10.9 1.9e-09 37.5 10.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MutS_III PF05192.18 KZN93739.1 - 0.077 13.2 0.2 0.19 11.9 0.2 1.8 2 0 0 2 2 2 0 MutS domain III Ribosomal_L10 PF00466.20 KZN93740.1 - 1.1e-22 80.0 0.0 2.3e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 KZN93740.1 - 2.2e-21 76.3 3.3 2.2e-21 76.3 3.3 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein RL10P_insert PF17777.1 KZN93740.1 - 2.8e-21 75.3 0.1 6.4e-21 74.1 0.0 1.6 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Holin_SPP1 PF04688.13 KZN93740.1 - 0.067 13.4 0.1 0.38 10.9 0.1 2.1 1 1 1 2 2 2 0 SPP1 phage holin WD40 PF00400.32 KZN93741.1 - 0.002 18.9 0.7 0.036 15.0 0.0 3.3 3 1 0 3 3 3 1 WD domain, G-beta repeat URO-D PF01208.17 KZN93742.1 - 6.8e-129 429.9 0.0 7.7e-129 429.8 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) dCMP_cyt_deam_1 PF00383.23 KZN93743.1 - 4.5e-22 77.8 0.0 5.8e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KZN93743.1 - 1.7e-19 69.9 0.0 2e-19 69.7 0.0 1.0 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 KZN93743.1 - 1e-05 25.6 2.2 0.093 12.8 0.7 2.2 1 1 1 2 2 2 2 Bd3614-like deaminase SNAD4 PF18750.1 KZN93743.1 - 0.00036 20.6 0.0 0.0023 18.0 0.0 1.9 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD2 PF18782.1 KZN93743.1 - 0.0041 17.2 0.0 0.019 15.1 0.0 1.9 1 1 0 1 1 1 1 Novel AID APOBEC clade 2 APOBEC_N PF08210.11 KZN93743.1 - 0.0098 15.8 0.1 0.018 14.9 0.1 1.5 1 1 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC2 PF18772.1 KZN93743.1 - 0.01 15.9 0.2 0.049 13.7 0.2 1.9 1 1 0 1 1 1 0 APOBEC2 NAD1 PF18778.1 KZN93743.1 - 0.011 15.8 0.1 0.036 14.1 0.1 1.9 1 1 0 1 1 1 0 Novel AID APOBEC clade 1 XOO_2897-deam PF14440.6 KZN93743.1 - 0.1 12.7 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase DnaJ_C PF01556.18 KZN93744.1 - 9.4e-39 132.9 0.3 1.2e-38 132.5 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KZN93744.1 - 9.7e-21 73.7 3.2 2.5e-20 72.4 3.2 1.7 1 1 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KZN93744.1 - 3.5e-15 56.1 19.4 5.9e-15 55.4 19.4 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KZN93744.1 - 1.2 9.2 9.7 0.55 10.3 2.5 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NMO PF03060.15 KZN93745.1 - 2.2e-34 119.3 2.4 7e-22 78.2 0.5 2.5 2 1 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 KZN93745.1 - 1.2e-08 34.3 0.8 0.0026 16.8 0.8 2.7 2 1 1 3 3 3 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KZN93745.1 - 2.3e-08 33.4 1.5 6.9e-08 31.9 1.4 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KZN93745.1 - 0.00023 20.4 0.0 0.00037 19.8 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KZN93745.1 - 0.097 12.1 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein Aldedh PF00171.22 KZN93746.1 - 7.9e-110 367.5 4.1 1.6e-60 205.0 0.1 3.0 1 1 2 3 3 3 3 Aldehyde dehydrogenase family DUF3197 PF11432.8 KZN93746.1 - 0.064 13.2 0.1 0.26 11.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3197) LuxC PF05893.14 KZN93746.1 - 0.21 10.6 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) NmrA PF05368.13 KZN93747.1 - 1.1e-15 57.9 0.0 1.3e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KZN93747.1 - 1.7e-10 41.1 0.0 3.8e-10 40.0 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KZN93747.1 - 8.7e-10 38.5 0.1 1.3e-09 37.9 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KZN93747.1 - 0.00014 21.0 0.1 0.00021 20.4 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 KZN93747.1 - 0.0022 18.2 0.1 0.0054 17.0 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KZN93747.1 - 0.011 15.8 0.0 0.057 13.5 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 KZN93747.1 - 0.11 11.8 0.0 0.32 10.3 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_1 PF00175.21 KZN93748.1 - 2.8e-16 60.1 0.0 4.7e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 KZN93748.1 - 3.7e-07 30.7 0.0 3.9e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Globin FAD_binding_6 PF00970.24 KZN93748.1 - 1.5e-06 28.4 0.0 3.3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KZN93748.1 - 2.9e-06 27.5 0.0 0.0014 18.8 0.1 2.8 2 1 1 3 3 3 2 Ferric reductase NAD binding domain DUF4754 PF15946.5 KZN93748.1 - 0.037 14.3 0.6 0.48 10.7 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4754) FAD_binding_8 PF08022.12 KZN93748.1 - 0.055 13.6 0.1 0.38 10.9 0.0 2.4 2 0 0 2 2 2 0 FAD-binding domain Protoglobin PF11563.8 KZN93748.1 - 0.081 12.8 0.1 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 Protoglobin Sulfate_transp PF00916.20 KZN93749.1 - 4.2e-111 371.4 19.5 5.7e-111 370.9 19.5 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KZN93749.1 - 3.7e-07 29.8 0.0 6.6e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KZN93749.1 - 0.00061 20.2 2.8 0.00061 20.2 2.8 3.8 2 2 1 3 3 3 1 Molybdate transporter of MFS superfamily MFS_1 PF07690.16 KZN93750.1 - 5.5e-26 91.3 68.6 5.4e-14 51.9 31.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pantoate_transf PF02548.15 KZN93751.1 - 2.2e-105 351.7 0.5 2.6e-105 351.5 0.5 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KZN93751.1 - 1.4e-06 27.9 0.5 2.8e-06 27.0 0.5 1.6 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Mg_chelatase_C PF13335.6 KZN93751.1 - 0.032 14.9 0.0 0.065 13.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal NanE PF04131.14 KZN93751.1 - 0.4 9.8 2.4 18 4.5 0.0 2.7 2 1 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase Rab5ip PF07019.12 KZN93752.1 - 1.7e-19 70.1 8.9 2.7e-19 69.5 8.9 1.3 1 1 0 1 1 1 1 Rab5-interacting protein (Rab5ip) SAM_2 PF07647.17 KZN93753.1 - 1.3e-08 34.8 0.1 2.7e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KZN93753.1 - 0.00039 20.8 0.1 0.00092 19.6 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4508 PF14969.6 KZN93753.1 - 0.088 13.1 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) TPR_19 PF14559.6 KZN93754.1 - 8.1e-20 71.1 15.8 9.9e-07 29.2 0.0 7.6 6 2 3 9 9 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KZN93754.1 - 5.4e-14 52.2 15.6 0.0051 17.0 0.0 7.5 8 1 1 9 9 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KZN93754.1 - 1.5e-12 46.9 2.2 0.032 14.6 0.0 6.9 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KZN93754.1 - 7.8e-12 45.0 18.0 0.0012 19.4 0.7 9.9 7 3 4 11 11 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 KZN93754.1 - 2.2e-11 44.2 8.7 0.00033 21.2 0.0 4.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KZN93754.1 - 4e-11 42.1 26.3 0.23 11.6 0.2 10.2 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_11 PF13414.6 KZN93754.1 - 1.9e-08 33.8 4.1 0.089 12.5 0.1 6.3 6 1 2 8 8 7 3 TPR repeat TPR_8 PF13181.6 KZN93754.1 - 2e-08 33.8 18.8 0.31 11.4 0.1 8.7 11 0 0 11 11 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 KZN93754.1 - 3e-08 33.2 22.1 0.68 9.9 0.0 10.0 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_7 PF13176.6 KZN93754.1 - 3.1e-08 33.1 15.7 0.23 11.6 0.0 8.2 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 KZN93754.1 - 1.2e-05 25.3 9.6 0.00014 22.0 0.3 5.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KZN93754.1 - 3e-05 24.2 20.5 0.13 12.6 0.1 7.0 7 2 1 8 8 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 KZN93754.1 - 5e-05 22.7 1.1 2.6 7.2 0.0 4.4 3 1 0 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.17 KZN93754.1 - 0.0037 17.7 1.6 0.29 11.6 0.4 3.6 2 1 0 3 3 3 1 Bacterial transcriptional activator domain NARP1 PF12569.8 KZN93754.1 - 0.006 15.5 3.1 2.3 7.0 0.1 3.9 2 2 2 4 4 4 1 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 KZN93754.1 - 0.0068 16.7 5.2 4.3 7.7 0.1 5.0 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KZN93754.1 - 0.014 16.0 13.8 2.6 8.9 0.0 7.4 10 0 0 10 10 6 0 Tetratricopeptide repeat SNAP PF14938.6 KZN93754.1 - 0.021 14.3 1.4 1.7 8.0 0.0 2.7 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP PPR PF01535.20 KZN93754.1 - 1.2 9.5 5.0 4.1 7.9 0.3 3.8 5 0 0 5 5 4 0 PPR repeat MFS_1 PF07690.16 KZN93755.1 - 3.8e-28 98.4 43.2 3.9e-24 85.3 33.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Haem_oxygenas_2 PF14518.6 KZN93756.1 - 1.5e-32 112.8 0.7 2.4e-32 112.2 0.7 1.3 1 0 0 1 1 1 1 Iron-containing redox enzyme DIOX_N PF14226.6 KZN93757.1 - 3e-08 34.4 0.0 4.7e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KZN93757.1 - 2.9e-07 30.9 0.0 6.5e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.28 KZN93758.1 - 8.4e-68 228.9 0.0 1.1e-67 228.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 KZN93758.1 - 8e-21 75.2 0.0 2.3e-20 73.7 0.0 1.7 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 KZN93758.1 - 3.3e-07 30.5 0.1 7.5e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 KZN93758.1 - 0.00073 20.2 0.1 0.0017 19.0 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KZN93758.1 - 0.054 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 HTH_31 PF13560.6 KZN93758.1 - 0.15 12.5 0.1 0.6 10.5 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain p450 PF00067.22 KZN93759.1 - 2.5e-34 118.8 0.0 3.3e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.18 KZN93760.1 - 1.5e-22 79.9 0.0 2.4e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KZN93760.1 - 8.7e-05 22.4 0.0 0.00022 21.1 0.0 1.7 1 1 0 1 1 1 1 Dimerisation domain Methyltransf_23 PF13489.6 KZN93760.1 - 0.00017 21.5 0.0 0.00048 20.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN93760.1 - 0.00036 21.2 0.0 0.2 12.4 0.0 2.8 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_2 PF00891.18 KZN93761.1 - 6e-24 84.5 0.0 9.2e-24 83.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 KZN93761.1 - 2.6e-05 24.1 0.1 6.1e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 Dimerisation domain Dimerisation2 PF16864.5 KZN93761.1 - 0.0041 17.1 0.0 0.0073 16.3 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain FAD_binding_3 PF01494.19 KZN93762.1 - 7.2e-17 61.6 0.0 2.2e-07 30.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KZN93762.1 - 1.5e-08 34.6 0.5 0.00059 19.5 0.0 2.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KZN93762.1 - 4.6e-06 26.1 0.0 3.8e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN93762.1 - 0.00014 22.0 0.0 0.00054 20.1 0.0 2.1 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KZN93762.1 - 0.00031 21.2 0.0 0.065 13.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KZN93762.1 - 0.00036 19.7 0.0 0.44 9.6 0.0 2.3 2 0 0 2 2 2 2 Squalene epoxidase GIDA PF01134.22 KZN93762.1 - 0.0021 17.2 0.0 0.0098 15.0 0.0 1.8 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KZN93762.1 - 0.0025 17.1 0.0 0.12 11.6 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KZN93762.1 - 0.0028 17.0 0.0 0.0048 16.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 KZN93762.1 - 0.0047 15.8 0.1 0.012 14.5 0.0 1.6 1 1 1 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.24 KZN93762.1 - 0.0088 15.2 1.1 0.059 12.4 0.1 2.4 2 1 1 3 3 3 1 FAD binding domain HI0933_like PF03486.14 KZN93762.1 - 0.028 13.1 0.0 0.11 11.1 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 KZN93762.1 - 0.12 11.4 0.1 0.3 10.1 0.1 1.8 1 1 0 1 1 1 0 Lycopene cyclase protein PEP_mutase PF13714.6 KZN93763.1 - 1.2e-65 221.3 3.1 1.3e-65 221.2 3.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF3336 PF11815.8 KZN93764.1 - 1.7e-46 157.3 2.4 2.8e-46 156.7 2.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KZN93764.1 - 9.9e-17 61.8 0.4 5.3e-16 59.4 0.1 2.3 2 1 0 2 2 2 1 Patatin-like phospholipase RHH_4 PF13467.6 KZN93764.1 - 0.035 14.0 0.0 0.088 12.7 0.0 1.6 1 0 0 1 1 1 0 Ribbon-helix-helix domain AAA_lid_2 PF17863.1 KZN93764.1 - 0.14 12.0 0.2 0.99 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA lid domain LRR_4 PF12799.7 KZN93765.1 - 2.8e-14 53.0 3.3 0.0013 19.1 0.0 4.6 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KZN93765.1 - 6.4e-14 51.5 11.3 1.5e-08 34.2 1.7 4.0 2 1 2 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 KZN93765.1 - 0.00074 19.1 0.2 0.028 13.9 0.2 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KZN93765.1 - 0.0026 18.1 7.8 18 6.4 0.1 6.3 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.6 KZN93765.1 - 0.057 13.5 13.4 0.93 9.7 0.5 5.0 5 0 0 5 5 5 0 Leucine Rich repeat Metallophos PF00149.28 KZN93766.1 - 4e-40 138.5 0.1 5.2e-40 138.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KZN93766.1 - 1.1e-22 80.2 2.7 1.4e-22 79.8 1.8 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain APH PF01636.23 KZN93767.1 - 3.2e-18 66.6 0.0 1.1e-17 64.8 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KZN93767.1 - 0.03 13.9 0.0 6.8 6.2 0.0 2.5 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 KZN93767.1 - 0.05 12.9 0.0 0.65 9.3 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Arf PF00025.21 KZN93768.1 - 6.4e-65 217.8 0.0 7.6e-65 217.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KZN93768.1 - 2.3e-10 40.2 0.0 5.9e-07 29.0 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KZN93768.1 - 3.7e-08 33.0 0.0 5e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KZN93768.1 - 1.1e-06 28.9 0.0 2.5e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KZN93768.1 - 1.1e-06 28.7 0.0 1.6e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KZN93768.1 - 3.6e-05 23.4 0.0 4.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KZN93768.1 - 0.00023 20.6 0.0 0.00027 20.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KZN93768.1 - 0.21 11.1 0.0 5.3 6.5 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.19 KZN93768.1 - 0.22 11.1 0.0 12 5.4 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2457 PF10446.9 KZN93769.1 - 1.1e-141 473.2 40.4 9e-123 410.9 23.0 3.5 3 1 1 4 4 4 3 Protein of unknown function (DUF2457) Abhydrolase_6 PF12697.7 KZN93770.1 - 5.8e-06 27.1 0.1 8.4e-06 26.5 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Senescence PF06911.12 KZN93771.1 - 0.0045 17.3 4.7 0.0069 16.7 4.7 1.3 1 0 0 1 1 1 1 Senescence-associated protein THDPS_N_2 PF14805.6 KZN93771.1 - 0.057 13.7 0.0 0.085 13.1 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal SipA_VBS PF17985.1 KZN93771.1 - 0.13 12.2 0.6 9.9 6.3 0.0 2.7 3 0 0 3 3 3 0 SipA vinculin binding site VPS13_C PF16909.5 KZN93771.1 - 2.8 7.7 3.7 2.3 8.0 2.0 1.7 1 1 1 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal IQ PF00612.27 KZN93773.1 - 0.00098 18.7 4.2 0.0037 16.9 0.4 2.8 2 0 0 2 2 2 1 IQ calmodulin-binding motif AflR PF08493.10 KZN93774.1 - 0.00029 20.4 0.8 0.00042 19.9 0.8 1.2 1 0 0 1 1 1 1 Aflatoxin regulatory protein Polysacc_deac_1 PF01522.21 KZN93774.1 - 0.083 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide deacetylase Zn_clus PF00172.18 KZN93775.1 - 1.3e-07 31.6 8.5 3e-07 30.4 8.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lactamase_B PF00753.27 KZN93776.1 - 8.1e-18 65.1 1.5 1.6e-16 60.9 1.5 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KZN93776.1 - 3.5e-07 29.9 0.1 5.3e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 KZN93776.1 - 0.00014 21.3 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KZN93776.1 - 0.0098 15.8 0.4 0.041 13.8 0.4 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain BLACT_WH PF17778.1 KZN93776.1 - 0.089 12.8 0.1 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain Vezatin PF12632.7 KZN93777.1 - 8.8e-68 228.7 0.0 1.7e-67 227.8 0.0 1.4 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes PCNA_N PF00705.18 KZN93778.1 - 1.3e-55 186.5 3.8 1.4e-55 186.4 2.5 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KZN93778.1 - 2.4e-51 173.2 0.0 5.6e-51 172.0 0.0 1.6 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 KZN93778.1 - 2.9e-07 30.2 0.1 3.8e-07 29.8 0.1 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 KZN93778.1 - 1.6e-05 24.1 0.4 0.00055 19.1 0.4 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 KZN93778.1 - 0.00065 18.9 0.3 0.0058 15.8 0.1 2.0 2 0 0 2 2 2 1 Hus1-like protein HRI1 PF16815.5 KZN93779.1 - 5.3e-30 104.8 0.7 1.6e-29 103.3 0.7 1.7 1 1 0 1 1 1 1 Protein HRI1 p450 PF00067.22 KZN93780.1 - 3.6e-46 157.9 0.0 4.9e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 SCIMP PF15050.6 KZN93781.1 - 0.37 11.3 2.2 1.3 9.5 0.1 2.7 3 0 0 3 3 3 0 SCIMP protein HemY_N PF07219.13 KZN93781.1 - 7.1 6.9 8.8 94 3.3 0.0 3.6 2 1 1 3 3 3 0 HemY protein N-terminus Sec61_beta PF03911.16 KZN93782.1 - 1.7e-17 63.2 0.8 2.3e-17 62.8 0.8 1.2 1 0 0 1 1 1 1 Sec61beta family SSF PF00474.17 KZN93783.1 - 1.2e-19 70.4 31.8 2e-19 69.8 31.8 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family zinc_ribbon_15 PF17032.5 KZN93784.1 - 0.0085 16.8 2.0 0.012 16.4 2.0 1.2 1 0 0 1 1 1 1 zinc-ribbon family zf-LITAF-like PF10601.9 KZN93784.1 - 2.8 8.3 9.4 7.1 7.0 1.0 2.2 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain Dynein_light PF01221.18 KZN93785.1 - 2.4e-11 43.8 0.0 3.4e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 RRM_1 PF00076.22 KZN93786.1 - 5.1e-76 250.5 1.0 1.5e-17 63.1 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KZN93786.1 - 2.5e-08 33.6 0.0 0.14 11.8 0.0 4.8 4 1 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KZN93786.1 - 6.6e-07 29.1 0.0 0.2 11.5 0.0 4.5 5 0 0 5 5 5 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KZN93786.1 - 1.7e-06 27.9 0.0 1.5 8.9 0.0 3.7 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KZN93786.1 - 6.5e-06 26.2 0.0 0.5 10.5 0.0 4.0 3 0 0 3 3 3 2 RNA recognition motif Limkain-b1 PF11608.8 KZN93786.1 - 4.5e-05 23.4 0.2 1.4 9.0 0.0 4.9 5 0 0 5 5 5 1 Limkain b1 RRM_3 PF08777.11 KZN93786.1 - 0.003 17.6 1.8 7.1 6.7 0.0 4.7 4 1 1 5 5 5 1 RNA binding motif TraH_2 PF06871.11 KZN93786.1 - 0.15 11.6 0.6 1.7 8.3 0.0 2.7 2 0 0 2 2 2 0 TraH_2 Arm-DNA-bind_4 PF14657.6 KZN93786.1 - 0.37 10.6 3.8 8.7 6.2 0.2 3.2 3 0 0 3 3 3 0 Arm DNA-binding domain TEA PF01285.18 KZN93787.1 - 1.7e-27 95.2 0.0 4.1e-27 94.0 0.0 1.7 1 0 0 1 1 1 1 TEA/ATTS domain Aldo_ket_red PF00248.21 KZN93788.1 - 7.2e-41 140.3 0.0 1.1e-40 139.7 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family GFA PF04828.14 KZN93789.1 - 8.6e-23 80.5 0.9 1.3e-22 80.0 0.9 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Comm PF15957.5 KZN93789.1 - 0.0063 16.9 0.1 0.0094 16.3 0.1 1.3 1 0 0 1 1 1 1 Commissureless Abhydrolase_6 PF12697.7 KZN93791.1 - 1.8e-21 77.7 0.5 2.4e-21 77.4 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KZN93791.1 - 0.0027 17.0 0.1 0.028 13.7 0.1 2.5 2 1 0 2 2 2 1 Serine aminopeptidase, S33 TMEM151 PF14857.6 KZN93791.1 - 0.11 11.3 0.2 0.19 10.6 0.2 1.3 1 0 0 1 1 1 0 TMEM151 family Glyco_hydro_76 PF03663.14 KZN93793.1 - 1.5e-136 455.7 18.2 1.7e-136 455.5 18.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Cloacin_immun PF03513.14 KZN93793.1 - 0.025 14.9 0.1 0.052 13.9 0.1 1.5 1 0 0 1 1 1 0 Cloacin immunity protein RXT2_N PF08595.11 KZN93795.1 - 0.16 12.0 11.2 0.16 11.9 11.2 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2796 PF10986.8 KZN93795.1 - 0.2 11.6 9.7 0.21 11.5 9.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) PBP1_TM PF14812.6 KZN93795.1 - 0.22 11.9 7.8 0.24 11.8 7.8 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1840 PF08895.11 KZN93795.1 - 0.33 11.3 8.0 0.4 11.0 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) MDM31_MDM32 PF08118.11 KZN93795.1 - 0.39 9.3 3.0 0.38 9.4 3.0 1.0 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins Prothymosin PF03247.14 KZN93795.1 - 0.41 11.1 36.3 0.51 10.8 36.3 1.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family DNA_pol_phi PF04931.13 KZN93795.1 - 0.47 8.5 27.0 0.47 8.5 27.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi D123 PF07065.14 KZN93795.1 - 0.52 9.4 7.4 0.49 9.5 7.4 1.0 1 0 0 1 1 1 0 D123 Tim54 PF11711.8 KZN93795.1 - 0.72 8.6 11.4 0.7 8.6 11.4 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Sigma70_ner PF04546.13 KZN93795.1 - 0.75 9.6 17.4 0.76 9.6 17.4 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF913 PF06025.12 KZN93795.1 - 0.82 8.6 7.6 0.82 8.6 7.6 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RPN2_C PF18004.1 KZN93795.1 - 0.86 9.5 15.4 0.96 9.4 15.4 1.0 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF3391 PF11871.8 KZN93795.1 - 0.91 10.1 9.4 0.9 10.1 9.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) LRRC37AB_C PF14914.6 KZN93795.1 - 0.92 9.4 5.8 0.96 9.3 5.8 1.0 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain CDC45 PF02724.14 KZN93795.1 - 1.1 7.5 18.1 1.2 7.3 18.1 1.0 1 0 0 1 1 1 0 CDC45-like protein CPSF100_C PF13299.6 KZN93795.1 - 1.6 8.9 10.5 1.7 8.8 10.5 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Mpp10 PF04006.12 KZN93795.1 - 1.8 6.9 24.4 1.8 6.9 24.4 1.0 1 0 0 1 1 1 0 Mpp10 protein EIIBC-GUT_N PF03612.14 KZN93795.1 - 1.8 8.3 6.2 1.8 8.3 6.2 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus RNA_pol_Rpc4 PF05132.14 KZN93795.1 - 2 8.8 8.2 2.3 8.6 8.2 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Connexin PF00029.19 KZN93795.1 - 2 8.1 9.1 2 8.1 9.1 1.0 1 0 0 1 1 1 0 Connexin DUF3464 PF11947.8 KZN93795.1 - 2.1 8.1 4.2 2.2 8.0 4.2 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 GNAT_acetyltr_2 PF13718.6 KZN93795.1 - 2.4 7.5 5.2 2.5 7.4 5.2 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Saw1 PF11561.8 KZN93795.1 - 2.4 7.6 8.6 2.3 7.7 8.6 1.0 1 0 0 1 1 1 0 Single strand annealing-weakened 1 Sec62 PF03839.16 KZN93795.1 - 2.4 7.6 5.6 2.5 7.5 5.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 SURF2 PF05477.11 KZN93795.1 - 2.7 7.6 13.0 2.9 7.5 13.0 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF2052 PF09747.9 KZN93795.1 - 2.7 8.1 22.6 3.2 7.8 22.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Vfa1 PF08432.10 KZN93795.1 - 2.7 8.3 12.8 2.9 8.2 12.8 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Pox_Ag35 PF03286.14 KZN93795.1 - 2.8 7.7 17.0 2.9 7.6 17.0 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Med4 PF10018.9 KZN93795.1 - 3.1 7.5 14.1 3.3 7.3 14.1 1.0 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF4746 PF15928.5 KZN93795.1 - 3.1 7.2 21.5 3.1 7.1 21.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) G0-G1_switch_2 PF15103.6 KZN93795.1 - 3.1 8.3 8.4 3.4 8.1 8.4 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 DDHD PF02862.17 KZN93795.1 - 3.2 7.9 4.7 3.2 7.9 4.7 1.0 1 0 0 1 1 1 0 DDHD domain TFB6 PF17110.5 KZN93795.1 - 3.3 7.4 11.7 3.4 7.4 11.7 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DDRGK PF09756.9 KZN93795.1 - 3.9 7.0 23.9 4.1 7.0 23.9 1.0 1 0 0 1 1 1 0 DDRGK domain MRNIP PF15749.5 KZN93795.1 - 4.4 8.1 10.8 5.1 7.9 10.8 1.1 1 0 0 1 1 1 0 MRN-interacting protein NOA36 PF06524.12 KZN93795.1 - 4.5 6.5 22.1 4.9 6.4 22.1 1.1 1 0 0 1 1 1 0 NOA36 protein DUF5523 PF17661.1 KZN93795.1 - 4.7 6.8 22.3 5.2 6.7 22.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5523) RPA43_OB PF17875.1 KZN93795.1 - 5.2 7.7 11.3 6.3 7.5 11.3 1.2 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Eapp_C PF10238.9 KZN93795.1 - 5.4 7.1 9.2 6 6.9 9.2 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein NPR3 PF03666.13 KZN93795.1 - 5.6 5.6 9.0 5.8 5.6 9.0 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CTU2 PF10288.9 KZN93795.1 - 5.6 7.2 8.5 6.4 7.0 8.5 1.1 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Zip PF02535.22 KZN93795.1 - 5.9 6.0 9.0 6.3 5.9 9.0 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter TRAP_alpha PF03896.16 KZN93795.1 - 6.3 5.9 15.3 6.5 5.9 15.3 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Paf1 PF03985.13 KZN93795.1 - 6.4 5.7 26.1 6.9 5.6 26.1 1.0 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.12 KZN93795.1 - 6.5 4.8 26.1 6.8 4.8 26.1 1.0 1 0 0 1 1 1 0 Nop14-like family Afi1 PF07792.12 KZN93795.1 - 6.6 7.2 10.1 7.2 7.1 10.1 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Presenilin PF01080.17 KZN93795.1 - 6.8 5.3 10.0 6.8 5.3 10.0 1.0 1 0 0 1 1 1 0 Presenilin SDA1 PF05285.12 KZN93795.1 - 7.1 6.0 25.5 7.9 5.8 25.5 1.0 1 0 0 1 1 1 0 SDA1 DUF4820 PF16091.5 KZN93795.1 - 7.3 5.9 11.2 7 5.9 11.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CLN3 PF02487.17 KZN93795.1 - 7.4 5.5 5.0 7.4 5.5 5.0 1.0 1 0 0 1 1 1 0 CLN3 protein AIF_C PF14721.6 KZN93795.1 - 7.8 6.9 7.5 8.3 6.8 7.5 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4637 PF15470.6 KZN93795.1 - 7.9 6.2 24.6 8.8 6.0 24.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Usp PF00582.26 KZN93795.1 - 9 6.8 9.3 9.9 6.7 9.3 1.1 1 0 0 1 1 1 0 Universal stress protein family Folate_carrier PF01770.18 KZN93795.1 - 9.2 4.9 5.8 9.4 4.9 5.8 1.0 1 0 0 1 1 1 0 Reduced folate carrier FHIPEP PF00771.20 KZN93795.1 - 9.5 4.5 7.3 9.3 4.6 7.3 1.0 1 0 0 1 1 1 0 FHIPEP family Amino_oxidase PF01593.24 KZN93796.1 - 9.4e-11 41.7 0.0 2.5e-08 33.7 0.0 2.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KZN93796.1 - 1.7e-10 41.0 0.2 3.7e-10 39.9 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KZN93796.1 - 9.4e-09 35.1 1.1 1.4e-08 34.6 0.6 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KZN93796.1 - 9.6e-08 31.5 1.0 1.7e-07 30.7 1.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KZN93796.1 - 5e-06 26.0 0.2 1.1e-05 24.9 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KZN93796.1 - 5.9e-06 25.2 2.0 9.3e-06 24.6 2.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 KZN93796.1 - 6.5e-06 25.6 0.2 1e-05 25.0 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KZN93796.1 - 1.5e-05 25.5 1.1 0.00019 21.9 0.9 2.7 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KZN93796.1 - 1.6e-05 24.4 0.0 2.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KZN93796.1 - 2.8e-05 23.9 3.0 0.00012 21.7 3.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KZN93796.1 - 7.3e-05 22.0 0.4 0.0001 21.6 0.4 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 KZN93796.1 - 0.00063 19.0 0.5 0.0011 18.2 0.5 1.3 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 KZN93796.1 - 0.0049 16.2 0.4 0.054 12.8 0.3 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 KZN93796.1 - 0.016 14.8 0.3 0.028 14.0 0.3 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AIRS PF00586.24 KZN93796.1 - 0.026 15.2 0.3 0.21 12.2 0.0 2.3 2 0 0 2 2 2 0 AIR synthase related protein, N-terminal domain Trp_halogenase PF04820.14 KZN93796.1 - 0.15 10.9 0.6 0.22 10.3 0.6 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_7 PF13241.6 KZN93796.1 - 0.15 12.5 0.0 0.26 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 KZN93796.1 - 0.21 10.6 0.1 0.34 9.9 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein ABC_tran PF00005.27 KZN93797.1 - 1.2e-40 139.2 0.4 1.1e-31 110.2 0.1 2.9 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KZN93797.1 - 1.3e-31 110.3 39.0 2.1e-22 80.1 16.3 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 KZN93797.1 - 5.1e-11 42.9 0.0 0.00011 22.1 0.0 4.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 KZN93797.1 - 1.3e-05 25.4 0.0 0.03 14.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KZN93797.1 - 1.6e-05 25.2 0.6 0.14 12.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.19 KZN93797.1 - 1.8e-05 24.3 0.9 0.0017 17.8 0.1 3.0 3 1 0 3 3 2 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KZN93797.1 - 5.6e-05 22.8 3.8 0.057 13.0 0.0 3.2 4 0 0 4 4 3 2 AAA domain RsgA_GTPase PF03193.16 KZN93797.1 - 9.8e-05 22.3 0.2 0.068 13.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KZN93797.1 - 0.00013 22.5 0.0 0.33 11.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KZN93797.1 - 0.00026 20.6 2.2 0.6 9.9 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 KZN93797.1 - 0.0012 18.8 0.0 0.14 12.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain TsaE PF02367.17 KZN93797.1 - 0.0023 17.9 0.0 0.081 12.9 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 KZN93797.1 - 0.0047 17.4 0.0 0.35 11.3 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KZN93797.1 - 0.0059 16.6 0.5 2.2 8.3 0.1 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KZN93797.1 - 0.0062 16.1 0.2 2.5 7.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 KZN93797.1 - 0.0088 16.1 0.3 5.9 7.0 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KZN93797.1 - 0.012 16.0 1.0 4.5 7.6 0.4 2.7 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 KZN93797.1 - 0.02 15.3 0.1 4.8 7.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 KZN93797.1 - 0.021 14.0 0.2 4.6 6.4 0.0 2.7 2 1 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 KZN93797.1 - 0.05 13.3 0.6 7.5 6.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KZN93797.1 - 0.081 13.0 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_15 PF13175.6 KZN93797.1 - 0.087 12.5 0.2 11 5.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.6 KZN93797.1 - 0.087 12.9 0.1 3.2 7.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 KZN93797.1 - 0.13 12.7 3.5 10 6.6 0.2 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KZN93797.1 - 0.14 12.0 2.1 0.12 12.3 0.1 1.8 2 0 0 2 2 1 0 Rad17 P-loop domain T2SSE PF00437.20 KZN93797.1 - 0.16 11.0 0.6 5.3 6.0 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.23 KZN93797.1 - 0.16 12.0 0.9 3.2 7.8 0.1 2.4 2 0 0 2 2 2 0 Dynamin family IstB_IS21 PF01695.17 KZN93797.1 - 0.31 10.7 2.2 20 4.9 0.0 3.4 4 0 0 4 4 3 0 IstB-like ATP binding protein cobW PF02492.19 KZN93797.1 - 0.34 10.5 1.9 7.8 6.1 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MFS_1 PF07690.16 KZN93798.1 - 1.6e-20 73.4 38.6 1.3e-17 63.7 19.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN93798.1 - 5.1e-05 22.3 9.2 5.1e-05 22.3 9.2 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KZN93798.1 - 0.0054 15.1 3.1 0.0077 14.6 2.0 1.8 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Lactonase PF10282.9 KZN93799.1 - 5.3e-86 289.0 0.0 7e-86 288.6 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller He_PIG PF05345.12 KZN93799.1 - 1.5 9.1 9.3 0.18 12.0 1.9 3.3 3 1 0 3 3 3 0 Putative Ig domain Amidase PF01425.21 KZN93800.1 - 1.9e-14 53.5 0.0 2.1e-14 53.3 0.0 1.0 1 0 0 1 1 1 1 Amidase XkdW PF09636.10 KZN93800.1 - 0.16 12.1 1.0 0.3 11.2 0.2 1.7 2 0 0 2 2 2 0 XkdW protein DUF3967 PF13152.6 KZN93800.1 - 0.25 11.2 1.1 0.46 10.3 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3967) Ank_2 PF12796.7 KZN93801.1 - 6.3e-48 161.3 12.6 1.9e-09 38.0 0.1 6.7 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN93801.1 - 3.7e-40 135.8 11.3 7.1e-06 26.5 0.0 10.3 6 2 3 10 10 10 7 Ankyrin repeats (many copies) Ank PF00023.30 KZN93801.1 - 4.1e-37 125.0 16.4 2.5e-05 24.5 0.4 11.9 12 0 0 12 12 12 5 Ankyrin repeat Ank_5 PF13857.6 KZN93801.1 - 7.5e-34 115.4 14.5 6e-09 36.0 0.0 9.0 6 2 3 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN93801.1 - 1.4e-32 108.0 9.0 2.4e-05 24.3 0.0 11.0 12 0 0 12 12 11 5 Ankyrin repeat AAA_22 PF13401.6 KZN93801.1 - 5.2e-07 30.0 0.1 1.8e-06 28.3 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KZN93801.1 - 1.5e-06 28.7 0.2 1.6e-05 25.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KZN93801.1 - 2.8e-06 27.3 0.1 1.6e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 NACHT domain ORC2 PF04084.14 KZN93801.1 - 1.2e-05 24.4 0.3 2.4e-05 23.4 0.3 1.4 1 0 0 1 1 1 1 Origin recognition complex subunit 2 AAA_19 PF13245.6 KZN93801.1 - 2.7e-05 24.5 0.0 7.3e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KZN93801.1 - 0.00042 20.7 0.0 0.0023 18.3 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 KZN93801.1 - 0.0014 17.9 0.1 0.27 10.4 0.2 2.2 1 1 1 2 2 2 1 KAP family P-loop domain DUF2075 PF09848.9 KZN93801.1 - 0.0083 15.4 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KZN93801.1 - 0.048 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 KZN93801.1 - 0.062 12.2 0.0 0.14 11.0 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.7 KZN93801.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region GvpD PF07088.11 KZN93801.1 - 0.14 10.8 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein DUF1147 PF06615.11 KZN93802.1 - 0.021 14.8 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) FAD_binding_4 PF01565.23 KZN93803.1 - 1.1e-28 99.8 3.6 1.3e-28 99.5 2.9 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KZN93803.1 - 3.1e-05 24.0 0.2 6e-05 23.1 0.2 1.4 1 0 0 1 1 1 1 Berberine and berberine like AMP-binding PF00501.28 KZN93804.1 - 1.8e-72 244.3 0.0 2.1e-72 244.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme LRR_4 PF12799.7 KZN93805.1 - 1.4e-31 108.0 32.1 4.4e-08 33.3 0.3 7.5 3 2 7 10 10 10 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KZN93805.1 - 1.5e-17 63.1 32.5 5.5e-07 29.3 2.4 6.2 3 1 3 6 6 6 5 Leucine rich repeat LRR_9 PF14580.6 KZN93805.1 - 5e-15 55.4 13.3 3.4e-08 33.2 2.8 3.7 1 1 3 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 KZN93805.1 - 6.8e-07 28.8 14.0 0.19 11.9 0.3 7.1 6 1 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 KZN93805.1 - 0.012 16.0 25.5 10 7.2 0.4 8.6 8 2 0 8 8 8 0 Leucine Rich Repeat NIF PF03031.18 KZN93806.1 - 2.8e-54 183.1 0.1 5.3e-54 182.2 0.1 1.5 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase ABC_membrane_2 PF06472.15 KZN93807.1 - 8.5e-87 291.0 0.0 8.5e-87 291.0 0.0 1.7 3 0 0 3 3 3 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KZN93807.1 - 2.9e-11 44.0 0.0 5.8e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter THOC7 PF05615.13 KZN93807.1 - 0.0087 16.3 0.2 0.017 15.4 0.2 1.4 1 0 0 1 1 1 1 Tho complex subunit 7 AAA_23 PF13476.6 KZN93807.1 - 0.01 16.4 1.1 2.3 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KZN93807.1 - 0.11 12.3 0.0 0.35 10.6 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain RuvB_N PF05496.12 KZN93807.1 - 0.17 11.7 0.0 0.44 10.3 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Clr2 PF10383.9 KZN93808.1 - 7.3e-33 114.4 0.0 2.6e-32 112.6 0.0 1.9 2 0 0 2 2 2 1 Transcription-silencing protein Clr2 Clr2_transil PF16761.5 KZN93808.1 - 1.6e-14 54.4 0.3 3.7e-14 53.3 0.3 1.6 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Gpr1_Fun34_YaaH PF01184.19 KZN93809.1 - 1.3e-84 283.0 12.5 1.5e-84 282.8 12.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family 2OG-FeII_Oxy PF03171.20 KZN93810.1 - 0.019 15.4 0.0 0.066 13.7 0.0 1.9 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KZN93810.1 - 0.046 14.5 0.0 0.081 13.7 0.0 1.4 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal tRNA-synt_2 PF00152.20 KZN93811.1 - 2.5e-64 217.3 0.0 3.2e-64 217.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KZN93811.1 - 2.3e-11 43.5 0.1 5.5e-11 42.3 0.1 1.7 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KZN93811.1 - 1.2e-06 28.2 0.0 0.0014 18.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti_2 PF13742.6 KZN93811.1 - 0.0014 18.8 0.0 0.032 14.4 0.0 2.1 1 1 1 2 2 2 2 OB-fold nucleic acid binding domain zf-Tim10_DDP PF02953.15 KZN93812.1 - 2.8e-23 81.3 0.7 3.4e-23 81.1 0.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Frag1 PF10277.9 KZN93815.1 - 2.1e-33 115.7 17.0 2.5e-33 115.5 17.0 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF4231 PF14015.6 KZN93815.1 - 5.1 7.6 6.3 0.71 10.4 1.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) DUF1240 PF06836.12 KZN93815.1 - 9.1 6.9 11.8 12 6.5 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1240) CLTH PF10607.9 KZN93816.1 - 4.1e-31 107.9 0.0 7.2e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KZN93816.1 - 5.4e-08 32.7 0.1 1e-07 31.8 0.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 KZN93816.1 - 0.00015 21.2 0.0 0.00031 20.2 0.0 1.5 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.6 KZN93816.1 - 0.00026 20.9 0.1 0.00044 20.1 0.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KZN93816.1 - 0.001 19.3 0.3 0.0019 18.5 0.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KZN93816.1 - 0.0036 17.1 0.8 0.0068 16.2 0.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KZN93816.1 - 0.011 15.5 0.3 0.021 14.7 0.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KZN93816.1 - 0.015 15.1 0.7 0.029 14.2 0.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KZN93816.1 - 0.028 14.3 0.4 0.05 13.5 0.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) LURAP PF14854.6 KZN93816.1 - 0.21 11.6 1.8 13 5.8 0.0 2.4 2 0 0 2 2 2 0 Leucine rich adaptor protein BTB PF00651.31 KZN93817.1 - 0.00057 20.1 0.0 0.0032 17.7 0.0 2.1 3 0 0 3 3 3 1 BTB/POZ domain PCI PF01399.27 KZN93818.1 - 8.6e-10 39.1 0.0 1.6e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 PCI domain DUF2498 PF10692.9 KZN93818.1 - 0.19 11.7 0.0 0.51 10.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2498) Ribosomal_L18A PF01775.17 KZN93819.1 - 1e-53 180.6 0.2 1.2e-53 180.3 0.2 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A CysA_C_terminal PF17850.1 KZN93819.1 - 0.074 13.6 0.0 0.13 12.9 0.0 1.4 1 0 0 1 1 1 0 CysA C-terminal regulatory domain NAD_binding_1 PF00175.21 KZN93820.1 - 3.3e-33 114.6 0.0 5e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KZN93820.1 - 1.7e-22 79.6 0.0 4.4e-22 78.3 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KZN93820.1 - 9.2e-09 35.6 0.0 4.5e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain HMG_box PF00505.19 KZN93821.1 - 6.5e-11 42.5 1.5 1.3e-10 41.5 1.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KZN93821.1 - 6.3e-06 26.7 3.0 2e-05 25.1 2.1 2.2 2 0 0 2 2 2 1 HMG-box domain Amidohydro_1 PF01979.20 KZN93822.1 - 3.5e-76 256.7 2.0 6.8e-76 255.8 0.9 1.8 2 0 0 2 2 2 1 Amidohydrolase family Urease_alpha PF00449.20 KZN93822.1 - 6.1e-56 188.0 1.0 1.1e-55 187.1 0.5 1.8 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 KZN93822.1 - 3.9e-40 135.8 0.1 1.5e-39 133.9 0.0 2.0 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.18 KZN93822.1 - 1.1e-38 131.5 0.5 5.8e-38 129.2 0.1 2.2 2 0 0 2 2 2 1 Urease, gamma subunit Amidohydro_3 PF07969.11 KZN93822.1 - 1.9e-09 37.6 0.6 1.3e-05 24.9 0.1 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.14 KZN93822.1 - 0.082 12.7 0.1 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 Amidohydrolase Ald_Xan_dh_C2 PF02738.18 KZN93825.1 - 0.1 11.0 0.0 0.12 10.8 0.0 1.0 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase Lactamase_B_2 PF12706.7 KZN93826.1 - 2.5e-08 33.7 0.0 6.7e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.14 KZN93826.1 - 4.7e-06 26.7 0.1 2.2e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 KZN93826.1 - 0.069 13.2 0.1 0.21 11.6 0.1 1.9 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF1656 PF07869.12 KZN93827.1 - 0.17 11.9 0.9 0.3 11.1 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) NPR2 PF06218.11 KZN93828.1 - 1.4e-134 449.2 0.0 1.2e-133 446.2 0.0 2.1 1 1 0 1 1 1 1 Nitrogen permease regulator 2 Ada3 PF10198.9 KZN93829.1 - 4e-47 159.7 0.1 4e-47 159.7 0.1 2.1 2 1 0 2 2 2 1 Histone acetyltransferases subunit 3 DUF5313 PF17240.2 KZN93830.1 - 0.043 14.3 0.1 0.08 13.4 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5313) Ribosomal_L15e PF00827.17 KZN93831.1 - 6.7e-88 293.4 12.5 8.3e-88 293.1 12.5 1.0 1 0 0 1 1 1 1 Ribosomal L15 HECT PF00632.25 KZN93832.1 - 3.3e-72 243.6 0.0 4.3e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) C1_1 PF00130.22 KZN93832.1 - 0.07 13.0 0.3 0.16 11.9 0.3 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DAO PF01266.24 KZN93833.1 - 1.6e-62 212.2 2.2 2e-62 211.9 2.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KZN93833.1 - 8.1e-06 26.0 0.2 2.5e-05 24.4 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KZN93833.1 - 0.00026 20.4 0.0 0.092 12.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KZN93833.1 - 0.00065 19.2 0.8 0.0091 15.4 0.8 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KZN93833.1 - 0.0007 18.9 0.2 0.044 13.0 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KZN93833.1 - 0.0056 17.2 0.0 0.36 11.4 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KZN93833.1 - 0.0068 15.7 0.1 0.024 13.9 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 KZN93833.1 - 0.015 14.6 0.1 3.1 7.0 0.1 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KZN93833.1 - 0.018 14.1 0.5 0.41 9.7 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 KZN93833.1 - 0.026 13.3 0.1 0.42 9.2 0.1 2.4 2 1 1 3 3 3 0 HI0933-like protein RelB_transactiv PF16181.5 KZN93833.1 - 0.092 13.0 0.6 0.3 11.3 0.0 2.1 3 0 0 3 3 3 0 RelB transactivation domain Fungal_trans PF04082.18 KZN93835.1 - 1.5e-12 47.1 0.2 1.5e-12 47.1 0.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF2387 PF09526.10 KZN93835.1 - 0.17 12.0 0.0 0.43 10.7 0.0 1.6 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) Fungal_trans PF04082.18 KZN93836.1 - 1.4e-21 76.7 0.0 2.5e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Iso_dh PF00180.20 KZN93837.1 - 1.7e-88 297.1 0.0 2e-88 296.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Fungal_trans PF04082.18 KZN93840.1 - 2.7e-23 82.4 2.0 6.3e-23 81.2 0.3 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain RRM_1 PF00076.22 KZN93841.1 - 9e-80 262.5 6.3 1.9e-20 72.4 0.2 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KZN93841.1 - 6.6e-29 99.9 0.5 5.3e-28 97.0 0.7 2.4 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 KZN93841.1 - 4.9e-12 45.5 0.5 0.01 15.4 0.0 5.2 3 2 2 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KZN93841.1 - 1e-05 25.5 1.8 1 9.4 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KZN93841.1 - 1.6e-05 24.9 0.5 6.7 6.9 0.0 5.5 5 1 0 5 5 5 1 RNA recognition motif CbiG_mid PF11761.8 KZN93841.1 - 0.00034 20.7 0.0 3.7 7.7 0.0 3.6 3 0 0 3 3 3 1 Cobalamin biosynthesis central region RRM_occluded PF16842.5 KZN93841.1 - 0.03 14.2 0.6 15 5.5 0.0 3.5 4 0 0 4 4 4 0 Occluded RNA-recognition motif CSD PF00313.22 KZN93841.1 - 0.14 12.0 2.8 37 4.3 0.0 3.6 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain YflT PF11181.8 KZN93841.1 - 0.23 12.0 11.2 0.1 13.1 1.1 3.1 3 0 0 3 3 2 0 Heat induced stress protein YflT OB_RNB PF08206.11 KZN93841.1 - 0.38 10.5 3.6 14 5.5 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain SOBP PF15279.6 KZN93841.1 - 0.43 11.1 13.3 0.59 10.7 12.2 1.8 1 1 0 1 1 1 0 Sine oculis-binding protein HECT PF00632.25 KZN93842.1 - 7.1e-83 278.6 0.0 3.6e-82 276.3 0.0 1.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 KZN93842.1 - 0.11 12.4 0.8 0.38 10.7 0.8 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif MRP-L27 PF09809.9 KZN93843.1 - 0.0067 16.2 2.6 0.019 14.8 1.1 2.4 1 1 1 2 2 2 1 Mitochondrial ribosomal protein L27 DUF5089 PF17002.5 KZN93843.1 - 0.016 15.1 1.8 0.022 14.6 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) Ribosomal_L14e PF01929.17 KZN93843.1 - 0.067 13.7 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L14 Utp14 PF04615.13 KZN93844.1 - 8.2e-209 695.9 83.6 8.2e-209 695.9 83.6 2.6 1 1 1 2 2 2 1 Utp14 protein Glyco_hydro81C PF17652.1 KZN93845.1 - 7.4e-169 561.5 7.2 9.4e-169 561.2 7.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KZN93845.1 - 9.8e-115 383.1 0.7 1.7e-114 382.3 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Metallophos PF00149.28 KZN93846.1 - 8e-09 36.3 0.0 2.2e-08 34.9 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KZN93846.1 - 6.7e-06 26.4 0.0 0.0048 17.1 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Ribosomal_S8e PF01201.22 KZN93847.1 - 1.1e-53 181.1 0.7 1.3e-53 180.9 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e TFIIF_alpha PF05793.12 KZN93849.1 - 0.88 8.1 13.2 1.3 7.5 13.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Presenilin PF01080.17 KZN93849.1 - 1.8 7.2 9.1 2.1 7.0 9.1 1.2 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 KZN93849.1 - 4.7 5.9 6.9 4.9 5.9 6.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 KZN93850.1 - 2.1e-36 126.7 7.9 1.8e-25 90.7 0.1 3.0 2 1 1 3 3 3 2 SPX domain Na_sulph_symp PF00939.19 KZN93850.1 - 6e-32 111.3 39.6 8.8e-32 110.8 39.6 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region Ribosomal_S7 PF00177.21 KZN93850.1 - 5.9e-26 90.9 0.0 3.6e-25 88.3 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e CitMHS PF03600.16 KZN93850.1 - 8.1e-24 84.3 65.8 1.4e-22 80.3 39.4 1.9 1 1 1 2 2 2 2 Citrate transporter DUF4220 PF13968.6 KZN93850.1 - 0.031 13.7 0.7 0.091 12.2 0.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Na_Ca_ex PF01699.24 KZN93851.1 - 8.7e-41 139.4 35.8 1.1e-21 77.4 16.7 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DOCK_N PF16172.5 KZN93852.1 - 6.8e-116 387.3 0.2 3.7e-115 384.8 0.0 2.2 3 0 0 3 3 3 1 DOCK N-terminus DHR-2 PF06920.13 KZN93852.1 - 5.7e-40 137.5 0.2 4.7e-39 134.4 0.2 2.0 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 KZN93852.1 - 2.2e-37 128.8 0.0 4.7e-37 127.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SH3_1 PF00018.28 KZN93852.1 - 2.4e-05 23.8 0.0 5.1e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KZN93852.1 - 3.3e-05 23.7 0.1 0.00026 20.8 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KZN93852.1 - 0.037 13.7 0.0 0.08 12.6 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain PI3K_C2 PF00792.24 KZN93852.1 - 0.17 11.8 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 Sec3_C PF09763.9 KZN93853.1 - 1.4e-226 754.2 0.1 2.1e-226 753.6 0.1 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KZN93853.1 - 1.8e-29 101.7 0.0 3.7e-29 100.7 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.6 KZN93853.1 - 0.0023 18.3 0.2 0.0076 16.6 0.2 1.9 1 0 0 1 1 1 1 Sec3 exocyst complex subunit SRP40_C PF05022.12 KZN93854.1 - 1.6e-16 60.9 0.1 6.6e-16 58.9 0.1 2.1 1 0 0 1 1 1 1 SRP40, C-terminal domain F-box-like PF12937.7 KZN93855.1 - 1.2e-06 28.3 0.1 4.9e-06 26.3 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KZN93855.1 - 0.0045 16.8 0.0 0.0094 15.8 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KZN93855.1 - 0.02 14.8 0.0 0.11 12.4 0.0 2.1 2 1 0 2 2 2 0 F-box p450 PF00067.22 KZN93856.1 - 3.7e-56 190.8 0.0 4.8e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1992 PF09350.10 KZN93858.1 - 7.2e-20 70.9 0.2 2.4e-19 69.3 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) SNARE_assoc PF09335.11 KZN93859.1 - 0.0054 17.2 3.8 0.0087 16.5 3.8 1.4 1 0 0 1 1 1 1 SNARE associated Golgi protein DUF3040 PF11239.8 KZN93859.1 - 0.14 12.5 1.5 0.31 11.4 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF4383 PF14325.6 KZN93859.1 - 0.45 10.8 5.7 0.93 9.8 5.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4383) CcmD PF04995.14 KZN93860.1 - 0.19 11.8 3.4 0.76 9.9 2.0 2.4 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF2459 PF09601.10 KZN93861.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2459) LOR PF04525.12 KZN93862.1 - 1.5e-07 31.2 0.1 2.8e-06 27.1 0.0 2.1 2 0 0 2 2 2 2 LURP-one-related MBOAT_2 PF13813.6 KZN93864.1 - 8.6e-18 64.4 3.5 3.4e-17 62.5 3.5 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF4282 PF14110.6 KZN93864.1 - 0.11 13.2 2.0 0.21 12.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) P5CR_dimer PF14748.6 KZN93865.1 - 2.7e-20 72.6 0.4 1.9e-19 69.8 0.2 2.1 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KZN93865.1 - 1.4e-15 57.6 0.1 3.3e-15 56.4 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KZN93865.1 - 0.0056 16.3 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA OCD_Mu_crystall PF02423.15 KZN93866.1 - 3e-13 49.4 0.0 7.6e-12 44.8 0.0 3.0 2 1 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KZN93866.1 - 1.2e-07 31.9 0.0 1.1e-05 25.5 0.0 2.9 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KZN93866.1 - 0.093 13.0 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Acetyltransf_8 PF13523.6 KZN93867.1 - 1.9e-49 167.1 0.0 2.7e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ECH_1 PF00378.20 KZN93868.1 - 5.1e-41 140.6 0.0 6.3e-41 140.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KZN93868.1 - 5.4e-26 91.9 0.0 6.1e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Cyclin_N PF00134.23 KZN93869.1 - 6.8e-13 48.5 0.0 2.3e-11 43.6 0.0 2.7 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin PF08613.11 KZN93869.1 - 1.8e-06 28.4 0.0 3.8e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Cyclin Glyco_hydro_12 PF01670.16 KZN93870.1 - 7.4e-43 147.0 7.7 1e-42 146.5 7.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 ERG2_Sigma1R PF04622.12 KZN93871.1 - 2.4e-97 324.4 0.2 2.8e-97 324.1 0.2 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein DUF3687 PF12459.8 KZN93871.1 - 0.028 13.9 0.1 0.07 12.7 0.1 1.7 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein UCR_6-4kD PF08997.10 KZN93871.1 - 0.076 13.0 0.3 16 5.5 0.0 2.5 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein VIT PF08487.10 KZN93872.1 - 1.8e-29 102.2 0.2 3.7e-29 101.2 0.2 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KZN93872.1 - 3.5e-28 98.5 0.0 7e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 KZN93872.1 - 2.5e-17 62.5 0.0 8.3e-17 60.9 0.0 1.9 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 KZN93872.1 - 2.1e-10 41.1 0.1 3.8e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KZN93872.1 - 1.1e-07 32.4 0.0 3.6e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KZN93872.1 - 0.00032 20.2 0.0 0.00065 19.2 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein PTPS PF01242.19 KZN93872.1 - 0.057 13.4 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase Amidohydro_2 PF04909.14 KZN93873.1 - 1.2e-33 117.1 0.0 1.5e-33 116.8 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 KZN93873.1 - 0.016 14.6 0.0 0.039 13.3 0.0 1.6 2 0 0 2 2 2 0 TatD related DNase ApbA PF02558.16 KZN93874.1 - 1.5e-28 99.3 0.0 2e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KZN93874.1 - 8.6e-26 90.6 0.0 1.5e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal PglD_N PF17836.1 KZN93874.1 - 0.0058 17.2 0.0 0.011 16.3 0.0 1.5 1 0 0 1 1 1 1 PglD N-terminal domain ThiF PF00899.21 KZN93874.1 - 0.11 11.8 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 ThiF family MFS_1 PF07690.16 KZN93876.1 - 8.1e-32 110.5 26.3 8.1e-32 110.5 26.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Pkinase PF00069.25 KZN93877.1 - 2.8e-16 59.7 0.0 1.2e-08 34.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KZN93877.1 - 1.8e-07 30.7 1.1 0.013 14.7 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KZN93877.1 - 0.065 13.1 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KZN93877.1 - 0.1 11.9 0.1 2.5 7.4 0.0 2.3 3 0 0 3 3 3 0 Kinase-like adh_short PF00106.25 KZN93879.1 - 4.5e-39 133.9 0.0 5.9e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN93879.1 - 7.8e-30 104.2 0.0 1.2e-29 103.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN93879.1 - 1.7e-09 37.9 0.1 5.4e-09 36.2 0.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KZN93879.1 - 3.7e-05 23.3 0.1 5.8e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KZN93879.1 - 9.9e-05 22.3 0.1 0.00015 21.7 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 KZN93879.1 - 0.00016 21.7 0.0 0.00024 21.2 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KZN93879.1 - 0.0002 21.6 0.0 0.00032 21.0 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KZN93879.1 - 0.0026 18.0 0.0 0.0046 17.2 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.19 KZN93879.1 - 0.003 16.6 0.0 0.0048 16.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KZN93879.1 - 0.051 13.0 0.1 0.07 12.5 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KZN93879.1 - 0.055 12.6 0.0 0.08 12.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 KZN93879.1 - 0.15 12.8 0.1 0.3 11.8 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans_2 PF11951.8 KZN93880.1 - 2.6e-08 33.1 0.5 5.2e-08 32.1 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN93880.1 - 0.00031 20.8 12.0 0.00057 19.9 12.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transferase PF02458.15 KZN93881.1 - 3.7e-05 22.6 0.0 0.00013 20.8 0.0 1.7 1 1 0 1 1 1 1 Transferase family HTH_36 PF13730.6 KZN93881.1 - 0.033 14.1 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain NAD_binding_4 PF07993.12 KZN93882.1 - 1.7e-29 102.8 0.0 2.3e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KZN93882.1 - 1.8e-09 37.4 0.0 5e-08 32.7 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KZN93882.1 - 0.00016 21.2 0.0 0.00064 19.2 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KZN93882.1 - 0.00061 18.9 0.0 0.096 11.7 0.0 2.5 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KZN93882.1 - 0.0017 18.3 0.0 0.0031 17.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KZN93882.1 - 0.0026 17.0 0.0 0.0045 16.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Pkinase PF00069.25 KZN93883.1 - 6.7e-25 87.9 0.0 9.2e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN93883.1 - 2.6e-10 40.1 0.0 3.7e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KZN93883.1 - 0.00048 20.1 0.0 0.013 15.4 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KZN93883.1 - 0.0026 17.1 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 KZN93883.1 - 0.015 14.9 0.0 0.037 13.6 0.0 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 KZN93883.1 - 0.03 13.9 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KZN93883.1 - 0.073 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ATP_bind_3 PF01171.20 KZN93885.1 - 9.7e-19 67.8 0.0 1.6e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 KZN93885.1 - 9.4e-18 63.4 2.3 9.4e-18 63.4 2.3 3.7 4 0 0 4 4 4 1 Zinc-ribbon RecR PF02132.15 KZN93885.1 - 0.0023 17.5 4.1 0.0023 17.5 4.1 2.6 3 0 0 3 3 3 1 RecR protein tRNA_Me_trans PF03054.16 KZN93885.1 - 0.081 11.7 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase zf-UBR PF02207.20 KZN93885.1 - 0.63 10.2 5.5 5.6 7.2 0.6 2.5 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Complex1_LYR_2 PF13233.6 KZN93886.1 - 1.8e-22 79.8 0.2 2.2e-22 79.6 0.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like CHD5 PF04420.14 KZN93886.1 - 0.089 12.6 0.1 0.12 12.3 0.1 1.3 1 1 0 1 1 1 0 CHD5-like protein RasGEF PF00617.19 KZN93887.1 - 2.8e-44 151.4 1.3 5e-44 150.6 1.3 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KZN93887.1 - 3.9e-14 52.7 0.0 1e-13 51.4 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif DEC-1_N PF04625.13 KZN93888.1 - 0.068 12.2 3.2 0.082 11.9 3.2 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF3275 PF11679.8 KZN93888.1 - 0.69 9.9 2.5 0.98 9.4 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Hamartin PF04388.12 KZN93888.1 - 0.82 8.3 6.4 1 8.0 6.4 1.0 1 0 0 1 1 1 0 Hamartin protein Nfu_N PF08712.11 KZN93889.1 - 9.1e-31 105.8 0.0 2.1e-29 101.4 0.0 2.4 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KZN93889.1 - 7.6e-28 96.5 0.2 1.4e-27 95.7 0.2 1.4 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.9 KZN93889.1 - 0.18 11.9 0.3 1.2 9.3 0.5 2.1 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus Sugar_tr PF00083.24 KZN93890.1 - 2.8e-76 257.2 23.4 3.1e-76 257.0 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN93890.1 - 7e-14 51.5 33.2 5.5e-09 35.4 17.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2079 PF09852.9 KZN93890.1 - 0.83 8.4 8.1 1.5 7.6 8.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) PSP1 PF04468.12 KZN93891.1 - 4.6e-28 97.3 2.6 7.4e-28 96.7 2.6 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region FRG1 PF06229.12 KZN93892.1 - 6.9e-54 182.5 0.2 9.9e-54 182.0 0.2 1.2 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 KZN93892.1 - 0.045 14.0 0.0 0.094 12.9 0.0 1.7 1 0 0 1 1 1 0 Fascin domain Frataxin_Cyay PF01491.16 KZN93892.1 - 0.1 12.7 0.1 0.36 10.9 0.0 1.9 2 0 0 2 2 2 0 Frataxin-like domain ADH_N PF08240.12 KZN93893.1 - 8.4e-35 119.0 1.9 1.6e-34 118.0 1.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN93893.1 - 2.9e-16 59.6 0.0 5.3e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KZN93893.1 - 6.3e-16 58.5 0.0 9.3e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KZN93893.1 - 6.2e-07 30.5 0.0 1.2e-06 29.6 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 KZN93893.1 - 0.00055 19.3 0.6 0.0008 18.7 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 KZN93893.1 - 0.0016 18.9 0.0 0.0032 17.9 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 KZN93893.1 - 0.021 14.1 0.2 0.077 12.2 0.1 1.8 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_3 PF03447.16 KZN93893.1 - 0.028 15.1 0.0 0.072 13.8 0.0 1.7 2 0 0 2 2 1 0 Homoserine dehydrogenase, NAD binding domain DUF2318 PF10080.9 KZN93893.1 - 0.031 14.4 0.7 9.8 6.4 0.2 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2318) NAD_binding_8 PF13450.6 KZN93893.1 - 0.04 14.2 0.1 0.095 12.9 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KZN93893.1 - 0.054 13.6 0.0 0.17 11.9 0.0 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KZN93893.1 - 0.073 13.3 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KZN93893.1 - 0.079 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.17 KZN93893.1 - 0.093 12.0 0.1 0.2 10.9 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KZN93893.1 - 0.13 11.3 0.4 0.18 10.8 0.4 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein XdhC_C PF13478.6 KZN93893.1 - 0.16 12.5 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain Vps52 PF04129.12 KZN93894.1 - 1.7e-119 399.9 0.0 2e-119 399.6 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 KZN93894.1 - 9.6e-08 30.9 0.0 1.4e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec3 THOC7 PF05615.13 KZN93894.1 - 0.0044 17.3 0.9 0.011 16.0 0.3 2.0 2 0 0 2 2 2 1 Tho complex subunit 7 Nbl1_Borealin_N PF10444.9 KZN93894.1 - 0.046 13.4 0.5 0.35 10.6 0.4 2.5 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal Sec8_exocyst PF04048.14 KZN93894.1 - 0.091 12.6 1.6 0.21 11.4 0.1 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain eIF-5a PF01287.20 KZN93895.1 - 3.5e-29 100.7 1.8 5e-29 100.2 1.8 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KZN93895.1 - 0.0032 17.5 0.0 0.0065 16.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Nitro_FeMo-Co PF02579.17 KZN93895.1 - 0.042 14.2 0.1 0.1 12.9 0.0 1.7 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor zf-RRN7 PF11781.8 KZN93896.1 - 1.1e-09 37.8 4.6 2.2e-09 36.8 4.6 1.5 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Yip1 PF04893.17 KZN93897.1 - 6.9e-16 58.4 14.8 1.1e-15 57.8 14.8 1.3 1 1 0 1 1 1 1 Yip1 domain RabGAP-TBC PF00566.18 KZN93898.1 - 2.3e-21 76.5 0.0 3.9e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MMS1_N PF10433.9 KZN93899.1 - 3.3e-90 303.0 0.0 6.9e-90 302.0 0.0 1.6 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KZN93899.1 - 0.00036 20.0 0.0 0.00078 18.8 0.0 1.5 1 0 0 1 1 1 1 CPSF A subunit region PQQ_3 PF13570.6 KZN93899.1 - 0.0014 19.1 0.5 1.5 9.4 0.1 4.5 5 0 0 5 5 5 1 PQQ-like domain Katanin_con80 PF13925.6 KZN93899.1 - 0.061 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 con80 domain of Katanin GTP_EFTU PF00009.27 KZN93900.1 - 6.8e-35 120.4 0.0 4.8e-34 117.6 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KZN93900.1 - 5.7e-19 68.2 0.1 1.7e-18 66.6 0.1 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KZN93900.1 - 2.2e-11 44.0 2.1 6.4e-10 39.3 0.0 3.5 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 KZN93900.1 - 3.3e-08 33.3 0.1 1.1e-07 31.7 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 KZN93900.1 - 3.7e-07 30.2 0.1 8.6e-06 25.8 0.0 3.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 KZN93900.1 - 0.00022 21.4 0.0 0.00066 19.9 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KZN93900.1 - 0.00071 19.4 0.0 0.0024 17.7 0.0 2.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Ras PF00071.22 KZN93900.1 - 0.04 13.5 0.0 0.29 10.7 0.0 2.5 2 1 0 2 2 2 0 Ras family RsgA_GTPase PF03193.16 KZN93900.1 - 0.081 12.8 1.2 0.84 9.5 0.2 3.1 3 1 0 3 3 3 0 RsgA GTPase Rhodanese PF00581.20 KZN93901.1 - 3.4e-11 43.6 0.0 5.5e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain p450 PF00067.22 KZN93902.1 - 4.3e-54 184.0 0.0 5.7e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SRP68 PF16969.5 KZN93903.1 - 3.9e-195 650.1 3.0 4.5e-195 649.9 3.0 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 PPR_2 PF13041.6 KZN93904.1 - 6.9e-21 74.2 1.2 1.3e-08 34.9 0.1 8.0 7 1 1 8 8 8 3 PPR repeat family PPR_3 PF13812.6 KZN93904.1 - 7.9e-19 67.5 0.0 7e-08 32.4 0.0 4.4 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.20 KZN93904.1 - 2.6e-16 58.7 3.9 0.022 15.0 0.0 9.6 9 0 0 9 9 9 4 PPR repeat PPR_long PF17177.4 KZN93904.1 - 1.3e-07 31.2 0.1 0.22 10.9 0.1 3.5 2 1 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KZN93904.1 - 4.6e-07 29.4 0.2 3.7 7.3 0.0 5.8 7 0 0 7 7 7 3 PPR repeat Glyco_trans_4_2 PF13477.6 KZN93904.1 - 0.19 11.8 0.0 0.44 10.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like MCM PF00493.23 KZN93905.1 - 1.8e-96 321.6 0.1 2.8e-96 320.9 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KZN93905.1 - 4.9e-31 107.2 0.0 1.7e-30 105.5 0.0 1.9 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 KZN93905.1 - 4.8e-24 84.6 0.5 1.1e-23 83.5 0.5 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KZN93905.1 - 3.5e-10 40.4 0.0 1.3e-09 38.6 0.0 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KZN93905.1 - 4.5e-06 26.2 0.0 5e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KZN93905.1 - 0.0049 16.7 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TFIIF_alpha PF05793.12 KZN93905.1 - 3.3 6.2 12.7 4.7 5.7 12.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Spo7 PF03907.13 KZN93906.1 - 6.3e-89 297.2 0.0 9.7e-89 296.6 0.0 1.3 1 0 0 1 1 1 1 Spo7-like protein Abhydrolase_1 PF00561.20 KZN93907.1 - 2.8e-19 69.8 0.0 3.8e-17 62.8 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KZN93907.1 - 1.1e-14 54.2 0.0 8.3e-14 51.4 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KZN93907.1 - 6.3e-12 46.6 12.6 4.2e-11 43.9 7.8 3.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.11 KZN93907.1 - 4e-05 23.1 0.0 6.7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 KZN93907.1 - 0.00017 21.3 0.0 0.0004 20.1 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 KZN93907.1 - 0.015 14.2 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 KZN93907.1 - 0.026 14.3 0.0 0.3 10.8 0.0 2.4 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KZN93907.1 - 0.041 13.7 0.1 0.45 10.3 0.0 2.4 3 0 0 3 3 3 0 alpha/beta hydrolase fold LIDHydrolase PF10230.9 KZN93907.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Chlorophyllase PF07224.11 KZN93907.1 - 0.13 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_5 PF12695.7 KZN93907.1 - 0.18 11.6 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family TatD_DNase PF01026.21 KZN93908.1 - 1.5e-36 126.1 0.0 2.7e-36 125.3 0.0 1.4 1 1 0 1 1 1 1 TatD related DNase Fungal_trans PF04082.18 KZN93909.1 - 6.9e-21 74.5 0.0 1.9e-20 73.0 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN93909.1 - 4.8e-09 36.2 11.9 7.2e-09 35.6 11.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GFO_IDH_MocA PF01408.22 KZN93910.1 - 1.4e-19 71.1 0.2 3.2e-19 69.9 0.1 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Prefoldin_2 PF01920.20 KZN93911.1 - 6e-25 87.3 8.8 7.9e-25 86.9 8.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 KZN93911.1 - 0.009 15.9 7.1 0.45 10.4 0.1 2.2 2 0 0 2 2 2 2 Prefoldin subunit DUF2205 PF10224.9 KZN93911.1 - 0.012 15.6 2.4 0.012 15.6 2.4 1.9 2 0 0 2 2 2 0 Short coiled-coil protein UCR_14kD PF02271.16 KZN93911.1 - 0.018 15.0 0.6 0.023 14.7 0.6 1.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit TACC_C PF05010.14 KZN93911.1 - 0.023 14.5 7.2 0.051 13.4 7.2 1.5 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal ATP-synt_D PF01813.17 KZN93911.1 - 0.038 13.8 3.1 1 9.2 0.3 2.1 2 0 0 2 2 2 0 ATP synthase subunit D HrpB7 PF09486.10 KZN93911.1 - 0.041 14.3 1.0 0.15 12.4 0.9 1.8 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) ZnuA PF01297.17 KZN93911.1 - 0.043 13.2 2.4 0.14 11.5 0.7 1.9 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic STAT_alpha PF01017.20 KZN93911.1 - 0.043 13.7 6.7 0.083 12.8 6.7 1.5 1 1 0 1 1 1 0 STAT protein, all-alpha domain FliE PF02049.18 KZN93911.1 - 0.078 13.1 4.1 0.87 9.8 1.1 2.1 2 0 0 2 2 2 0 Flagellar hook-basal body complex protein FliE Fib_alpha PF08702.10 KZN93911.1 - 0.089 13.0 5.5 0.52 10.5 4.7 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family CLZ PF16526.5 KZN93911.1 - 0.098 13.0 4.7 4.1 7.8 1.3 2.1 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels V_ATPase_I PF01496.19 KZN93911.1 - 0.099 10.6 2.8 0.1 10.5 2.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LXG PF04740.12 KZN93911.1 - 0.099 12.3 6.6 1.2 8.8 0.9 2.1 2 0 0 2 2 2 0 LXG domain of WXG superfamily Occludin_ELL PF07303.13 KZN93911.1 - 0.11 13.2 4.9 4 8.2 0.3 2.1 1 1 1 2 2 2 0 Occludin homology domain PI3K_P85_iSH2 PF16454.5 KZN93911.1 - 0.19 11.3 9.3 0.26 10.9 3.3 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DASH_Dad3 PF08656.10 KZN93911.1 - 0.2 11.7 5.2 1.3 9.1 5.2 2.1 1 1 0 1 1 1 0 DASH complex subunit Dad3 Spc24 PF08286.11 KZN93911.1 - 0.49 10.7 8.0 0.34 11.2 2.4 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 OmpH PF03938.14 KZN93911.1 - 0.81 10.0 13.9 1.1 9.5 6.8 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Fzo_mitofusin PF04799.13 KZN93911.1 - 0.84 9.2 5.5 6.3 6.3 1.5 2.1 1 1 1 2 2 2 0 fzo-like conserved region Wtap PF17098.5 KZN93911.1 - 0.89 9.5 6.6 17 5.3 6.5 2.1 1 1 0 1 1 1 0 WTAP/Mum2p family MIP-T3_C PF17749.1 KZN93911.1 - 1.3 9.0 10.2 3.4 7.6 3.5 2.1 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region MCU PF04678.13 KZN93911.1 - 1.9 8.6 4.8 0.89 9.6 1.5 1.8 1 1 0 2 2 2 0 Mitochondrial calcium uniporter GrpE PF01025.19 KZN93911.1 - 3.5 7.3 9.1 17 5.1 9.1 1.8 1 1 0 1 1 1 0 GrpE HA2 PF04408.23 KZN93912.1 - 1.2e-19 70.6 0.0 1.2e-19 70.6 0.0 2.5 3 0 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KZN93912.1 - 1.1e-15 57.7 0.0 3.6e-15 56.1 0.0 1.9 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KZN93912.1 - 2.4e-15 56.8 0.0 6.4e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KZN93912.1 - 7.7e-08 32.3 0.2 5.9e-07 29.4 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KZN93912.1 - 1.4e-05 25.4 0.3 5.1e-05 23.6 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KZN93912.1 - 0.00036 20.9 0.4 0.001 19.4 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KZN93912.1 - 0.00075 19.3 1.0 0.0012 18.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain DUF2075 PF09848.9 KZN93912.1 - 0.00079 18.8 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KZN93912.1 - 0.0032 17.2 0.0 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KZN93912.1 - 0.0045 16.1 0.0 0.014 14.5 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein SRP54 PF00448.22 KZN93912.1 - 0.006 16.2 0.4 0.026 14.2 0.4 2.1 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.15 KZN93912.1 - 0.0085 16.1 0.1 2.7 7.9 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 KZN93912.1 - 0.01 15.9 0.2 0.084 12.9 0.2 2.3 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 KZN93912.1 - 0.011 15.7 0.1 0.02 14.9 0.1 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_7 PF12775.7 KZN93912.1 - 0.031 13.8 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KZN93912.1 - 0.032 14.6 0.0 0.078 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KZN93912.1 - 0.034 14.3 1.0 0.16 12.1 0.1 2.7 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 KZN93912.1 - 0.05 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 KaiC NACHT PF05729.12 KZN93912.1 - 0.06 13.3 1.1 0.83 9.5 0.0 2.9 3 0 0 3 3 3 0 NACHT domain ABC_tran PF00005.27 KZN93912.1 - 0.062 13.8 0.0 0.2 12.1 0.0 1.9 1 0 0 1 1 1 0 ABC transporter PhoH PF02562.16 KZN93912.1 - 0.07 12.6 0.0 0.22 10.9 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein cobW PF02492.19 KZN93912.1 - 0.11 12.1 0.1 0.61 9.6 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DAD PF02109.16 KZN93915.1 - 2.9e-46 156.3 0.1 3.8e-46 155.9 0.1 1.2 1 0 0 1 1 1 1 DAD family Fungal_trans PF04082.18 KZN93916.1 - 2.5e-20 72.6 0.1 4.6e-20 71.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN93916.1 - 5.1e-08 32.9 12.4 5.1e-08 32.9 12.4 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KZN93917.1 - 1.6e-71 241.5 14.4 3.4e-71 240.4 14.4 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN93917.1 - 5e-23 81.6 21.0 5.6e-23 81.4 15.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF86 PF01934.17 KZN93918.1 - 0.062 13.2 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF86 Glyco_hydro_43 PF04616.14 KZN93919.1 - 4.6e-66 223.1 1.6 6e-66 222.7 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KZN93919.1 - 3.8e-33 114.9 0.0 5.2e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_hydro_3 PF00933.21 KZN93920.1 - 8.5e-55 186.4 0.0 1.3e-54 185.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KZN93920.1 - 1.4e-50 172.1 0.0 2.3e-50 171.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KZN93920.1 - 3.4e-24 84.7 0.1 6.6e-24 83.8 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KZN93920.1 - 4.2e-10 39.6 0.0 7.1e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Zn_clus PF00172.18 KZN93921.1 - 2.9e-08 33.7 12.4 5.3e-08 32.8 12.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_A8 PF01252.18 KZN93921.1 - 0.13 12.5 0.1 0.34 11.1 0.1 1.7 1 1 0 1 1 1 0 Signal peptidase (SPase) II DUF1768 PF08719.11 KZN93922.1 - 6.4e-50 169.5 1.0 8.2e-50 169.2 0.5 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1768) Abhydrolase_1 PF00561.20 KZN93923.1 - 2.2e-30 106.2 0.2 3.7e-30 105.4 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KZN93923.1 - 4.4e-27 94.9 0.3 6.3e-18 64.9 0.2 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KZN93923.1 - 5.7e-18 66.3 0.0 7.5e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KZN93923.1 - 3e-07 30.1 0.2 0.0033 16.9 0.0 2.4 2 1 0 2 2 2 2 Prolyl oligopeptidase family DUF1749 PF08538.10 KZN93923.1 - 0.00027 20.1 0.1 0.00049 19.3 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) Peptidase_S15 PF02129.18 KZN93923.1 - 0.00066 19.4 0.0 0.24 10.9 0.0 2.2 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.7 KZN93923.1 - 0.0012 18.6 0.1 0.19 11.5 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KZN93923.1 - 0.0018 18.1 0.0 0.0049 16.7 0.0 1.7 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.18 KZN93923.1 - 0.0038 16.8 0.0 0.15 11.6 0.0 2.6 2 1 1 3 3 3 1 Dienelactone hydrolase family Ser_hydrolase PF06821.13 KZN93923.1 - 0.0047 16.8 0.0 0.025 14.4 0.0 2.0 2 0 0 2 2 2 1 Serine hydrolase DUF915 PF06028.11 KZN93923.1 - 0.0073 15.7 0.1 0.019 14.3 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase2 PF12740.7 KZN93923.1 - 0.0094 14.9 0.0 0.018 14.0 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme PAF-AH_p_II PF03403.13 KZN93923.1 - 0.017 13.6 0.1 1.1 7.7 0.0 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II UPF0227 PF05728.12 KZN93923.1 - 0.092 12.7 0.0 4.3 7.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Chlorophyllase PF07224.11 KZN93923.1 - 0.14 11.1 0.1 0.36 9.8 0.1 1.7 1 1 0 1 1 1 0 Chlorophyllase FSH1 PF03959.13 KZN93923.1 - 0.15 11.7 0.5 1.3 8.6 0.1 2.2 1 1 1 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.10 KZN93923.1 - 0.18 11.9 0.0 0.66 10.1 0.0 1.9 2 0 0 2 2 2 0 TAP-like protein DUF3108 PF11306.8 KZN93924.1 - 0.052 13.5 0.0 0.065 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3108) Goodbye PF17109.5 KZN93925.1 - 1.9e-19 70.3 0.0 1e-18 67.9 0.0 2.3 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain AAA_16 PF13191.6 KZN93925.1 - 0.0013 19.1 0.4 0.32 11.3 0.0 3.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KZN93925.1 - 0.033 14.5 0.0 0.13 12.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.16 KZN93926.1 - 5e-32 111.2 46.0 2.8e-21 75.9 14.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MIT PF04212.18 KZN93929.1 - 0.0049 16.9 0.1 0.011 15.8 0.1 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Aminotran_1_2 PF00155.21 KZN93930.1 - 1.4e-43 149.5 0.0 1.6e-43 149.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II TPR_2 PF07719.17 KZN93931.1 - 1.3e-08 34.3 13.2 0.0044 17.0 0.0 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 KZN93931.1 - 9.4e-06 25.2 4.5 0.13 12.1 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KZN93931.1 - 9.2e-05 22.0 9.2 1.4 8.6 0.1 6.3 7 0 0 7 7 7 2 TPR repeat TPR_19 PF14559.6 KZN93931.1 - 0.00025 21.5 7.3 0.94 10.0 0.1 4.9 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KZN93931.1 - 0.03 15.1 14.0 2.6 9.1 0.2 6.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_4 PF07721.14 KZN93931.1 - 0.043 14.4 4.5 8.2 7.4 0.2 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KZN93931.1 - 0.32 11.7 2.3 37 5.2 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KZN93931.1 - 0.34 11.2 6.9 2.5 8.5 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KZN93931.1 - 0.38 11.2 3.7 4.2e+02 1.7 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KZN93931.1 - 3.6 8.3 16.3 1.4 9.7 0.2 6.1 8 1 1 9 9 9 0 Tetratricopeptide repeat Pes-10 PF07149.11 KZN93932.1 - 0.48 9.4 3.6 0.64 9.0 3.6 1.1 1 0 0 1 1 1 0 Pes-10 DUF4637 PF15470.6 KZN93932.1 - 4.6 7.0 5.3 7.5 6.3 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Fungal_trans PF04082.18 KZN93933.1 - 4.3e-06 26.0 0.1 7.4e-06 25.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN93933.1 - 0.0021 18.1 11.3 0.0033 17.5 11.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RlmM_FDX PF18125.1 KZN93938.1 - 0.06 13.8 0.0 0.085 13.4 0.0 1.2 1 0 0 1 1 1 0 RlmM ferredoxin-like domain Tautomerase PF01361.21 KZN93939.1 - 0.057 13.4 0.3 5.3 7.0 0.0 2.7 1 1 2 3 3 3 0 Tautomerase enzyme CENP-F_C_Rb_bdg PF10490.9 KZN93939.1 - 0.096 12.1 3.2 15 5.1 0.0 4.0 4 2 1 5 5 5 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 Imm21 PF15589.6 KZN93939.1 - 0.14 12.2 3.9 10 6.1 0.2 2.8 1 1 2 3 3 3 0 Immunity protein 21 DUF3330 PF11809.8 KZN93942.1 - 0.002 18.2 0.0 0.0046 17.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3330) zf-RING_2 PF13639.6 KZN93942.1 - 0.0076 16.6 8.4 0.014 15.7 8.4 1.5 1 0 0 1 1 1 1 Ring finger domain RINGv PF12906.7 KZN93942.1 - 0.075 13.2 9.0 0.18 12.0 9.0 1.7 1 0 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 KZN93942.1 - 0.35 10.5 7.4 0.72 9.5 7.4 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type CDC45 PF02724.14 KZN93943.1 - 0.036 12.4 31.1 0.042 12.1 31.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KZN93943.1 - 0.045 12.0 39.2 0.053 11.7 39.2 1.0 1 0 0 1 1 1 0 Nop14-like family DDHD PF02862.17 KZN93943.1 - 0.097 12.8 5.7 0.12 12.6 5.7 1.2 1 0 0 1 1 1 0 DDHD domain SpoIIP PF07454.11 KZN93943.1 - 0.1 12.1 17.8 0.12 11.8 17.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Lin-8 PF03353.15 KZN93943.1 - 0.1 12.1 17.1 0.1 12.2 17.1 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Tim54 PF11711.8 KZN93943.1 - 0.1 11.3 20.6 0.12 11.1 20.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4050 PF13259.6 KZN93943.1 - 0.13 12.5 9.2 0.16 12.3 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) SpoIIIAH PF12685.7 KZN93943.1 - 0.15 11.9 16.4 0.16 11.8 16.4 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein CCSAP PF15748.5 KZN93943.1 - 0.2 11.8 20.8 0.24 11.5 20.8 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated BUD22 PF09073.10 KZN93943.1 - 0.25 10.6 32.5 0.28 10.5 32.5 1.0 1 0 0 1 1 1 0 BUD22 DUF4045 PF13254.6 KZN93943.1 - 0.45 10.1 14.7 0.51 9.9 14.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Paf1 PF03985.13 KZN93943.1 - 0.6 9.1 44.7 0.73 8.8 44.7 1.2 1 0 0 1 1 1 0 Paf1 SDA1 PF05285.12 KZN93943.1 - 0.73 9.2 42.4 0.9 8.9 42.4 1.1 1 0 0 1 1 1 0 SDA1 DUF5308 PF17233.2 KZN93943.1 - 1 9.6 4.9 1.2 9.3 4.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) YL1 PF05764.13 KZN93943.1 - 1 9.4 38.0 1.2 9.2 38.0 1.1 1 0 0 1 1 1 0 YL1 nuclear protein SMN PF06003.12 KZN93943.1 - 1.9 7.7 9.0 2.4 7.3 9.0 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Endostatin PF06482.11 KZN93943.1 - 2.5 7.5 5.0 2.8 7.3 5.0 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin LTV PF04180.14 KZN93943.1 - 2.7 7.6 23.7 3.2 7.4 23.7 1.0 1 0 0 1 1 1 0 Low temperature viability protein DUF2151 PF10221.9 KZN93943.1 - 3 6.3 15.5 3.4 6.2 15.5 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator MDM1 PF15501.6 KZN93943.1 - 3.1 6.9 27.8 3.6 6.6 27.8 1.0 1 0 0 1 1 1 0 Nuclear protein MDM1 Mpp10 PF04006.12 KZN93943.1 - 3.1 6.1 44.5 3.7 5.9 44.5 1.0 1 0 0 1 1 1 0 Mpp10 protein DUF913 PF06025.12 KZN93943.1 - 3.2 6.7 15.7 3.6 6.5 15.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Peptidase_S64 PF08192.11 KZN93943.1 - 3.8 5.9 11.4 4.3 5.7 11.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 NPR3 PF03666.13 KZN93943.1 - 4.5 6.0 18.6 5 5.8 18.6 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MCM_bind PF09739.9 KZN93943.1 - 5.3 5.4 14.2 5.8 5.2 14.2 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Gti1_Pac2 PF09729.9 KZN93943.1 - 6.7 6.8 10.7 8.1 6.5 10.7 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family TP53IP5 PF15331.6 KZN93943.1 - 7.4 6.7 10.9 8.4 6.5 10.9 1.0 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 SAPS PF04499.15 KZN93943.1 - 7.6 5.2 18.1 8.9 5.0 18.1 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SLC12 PF03522.15 KZN93943.1 - 7.7 5.4 13.1 9.2 5.2 13.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Apt1 PF10351.9 KZN93943.1 - 7.8 5.2 11.4 8.9 5.0 11.4 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAM60A PF15396.6 KZN93943.1 - 9.4 6.2 10.1 12 5.9 10.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Dimer_Tnp_hAT PF05699.14 KZN93944.1 - 8.8e-15 54.3 0.1 1.2e-12 47.4 0.0 2.6 2 0 0 2 2 2 2 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KZN93944.1 - 0.0015 18.9 0.1 0.0035 17.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) Hydrophobin PF01185.18 KZN93945.1 - 0.0014 19.2 7.1 0.0021 18.6 7.1 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Granulin PF00396.18 KZN93945.1 - 0.021 15.2 3.3 0.021 15.2 3.3 2.2 2 0 0 2 2 2 0 Granulin RNase_H PF00075.24 KZN93946.1 - 0.001 19.2 0.1 0.0021 18.2 0.1 1.5 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.27 KZN93946.1 - 0.0074 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hydrophobin PF01185.18 KZN93947.1 - 0.0013 19.3 7.3 0.002 18.7 7.3 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Granulin PF00396.18 KZN93947.1 - 0.021 15.2 3.3 0.021 15.2 3.3 2.2 2 0 0 2 2 2 0 Granulin Hydrophobin PF01185.18 KZN93948.1 - 0.0013 19.3 6.8 0.002 18.7 6.8 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Granulin PF00396.18 KZN93948.1 - 0.016 15.5 3.2 0.016 15.5 3.2 2.2 2 0 0 2 2 2 0 Granulin Hydrophobin PF01185.18 KZN93949.1 - 6.9e-05 23.4 6.4 0.0001 22.9 6.4 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Granulin PF00396.18 KZN93949.1 - 0.004 17.4 2.8 0.004 17.4 2.8 2.2 2 0 0 2 2 2 1 Granulin Zn_ribbon_17 PF17120.5 KZN93952.1 - 0.0037 16.9 9.4 0.0069 16.0 9.4 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 KZN93952.1 - 0.018 15.3 9.8 0.028 14.7 9.8 1.3 1 0 0 1 1 1 0 Ring finger domain zf-ANAPC11 PF12861.7 KZN93952.1 - 0.14 12.2 1.7 0.22 11.6 1.7 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 KZN93952.1 - 0.15 12.0 9.9 0.63 10.0 10.3 1.8 1 1 1 2 2 2 0 PHD-finger zf-rbx1 PF12678.7 KZN93952.1 - 0.54 10.6 8.5 1.4 9.3 8.5 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger domain RINGv PF12906.7 KZN93952.1 - 4.8 7.4 11.0 8 6.7 11.0 1.4 1 0 0 1 1 1 0 RING-variant domain PHD_4 PF16866.5 KZN93952.1 - 5.2 7.2 9.7 4.4 7.5 4.2 2.3 1 1 1 2 2 2 0 PHD-finger Ank_2 PF12796.7 KZN93953.1 - 9.4e-42 141.5 5.7 2.4e-10 40.8 0.0 5.1 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN93953.1 - 1.4e-30 105.3 16.2 8.9e-09 35.7 0.1 8.1 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN93953.1 - 1.5e-29 98.8 11.7 3.1e-06 27.1 0.1 9.8 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 KZN93953.1 - 1.8e-29 101.4 19.0 1.5e-11 44.3 0.2 8.0 4 3 4 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 KZN93953.1 - 9.7e-24 82.7 19.2 1.1e-07 31.9 0.1 8.9 9 0 0 9 9 9 6 Ankyrin repeat F-box-like PF12937.7 KZN93953.1 - 7e-06 25.8 1.2 9.7e-06 25.4 0.2 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KZN93953.1 - 0.00018 21.3 0.2 0.00031 20.5 0.2 1.4 1 0 0 1 1 1 1 F-box domain SLATT_5 PF18160.1 KZN93955.1 - 5.4 6.3 6.0 0.5 9.7 1.5 1.5 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Kdo PF06293.14 KZN93956.1 - 6e-06 25.8 0.0 1.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KZN93956.1 - 0.00039 19.9 0.0 0.00091 18.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KZN93956.1 - 0.0039 17.1 0.1 0.0039 17.1 0.1 3.9 2 2 2 4 4 4 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN93956.1 - 0.09 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF2828 PF11443.8 KZN93956.1 - 0.14 10.2 0.1 0.2 9.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) NinG PF05766.12 KZN93956.1 - 1.1 9.2 6.6 1.9 8.4 6.6 1.2 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein ORC_WH_C PF18137.1 KZN93956.1 - 1.6 8.8 5.9 4.2 7.5 5.9 1.7 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Casc1_N PF15927.5 KZN93956.1 - 3.7 7.2 20.3 7.5 6.2 20.3 1.4 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus zf-BED PF02892.15 KZN93957.1 - 0.024 14.7 4.4 0.034 14.2 2.5 2.1 2 0 0 2 2 2 0 BED zinc finger Elongin_A PF06881.11 KZN93957.1 - 0.04 14.4 0.3 0.056 14.0 0.3 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF4451 PF14616.6 KZN93957.1 - 0.079 13.2 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) HrpE PF06188.12 KZN93959.1 - 0.001 19.0 0.0 1.4 8.7 0.0 3.0 1 1 2 3 3 3 2 HrpE/YscL/FliH and V-type ATPase subunit E FIVAR PF07554.13 KZN93959.1 - 0.0085 16.8 9.2 14 6.5 0.2 4.5 1 1 0 2 2 2 1 FIVAR domain DUF948 PF06103.11 KZN93959.1 - 0.047 13.9 6.2 23 5.3 0.1 4.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) UAF_Rrn10 PF05234.11 KZN93959.1 - 1.7 8.9 18.4 61 3.9 0.3 6.3 2 1 5 7 7 7 0 UAF complex subunit Rrn10 Zn_clus PF00172.18 KZN93962.1 - 1.4e-08 34.7 13.3 2.9e-08 33.7 13.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_8 PF13181.6 KZN93963.1 - 0.042 14.1 0.3 23 5.5 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Ank_2 PF12796.7 KZN93965.1 - 1.5e-55 185.8 7.5 1.2e-12 48.2 0.0 6.2 3 2 2 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KZN93965.1 - 3.9e-44 143.5 16.6 0.0011 19.2 0.1 13.3 13 0 0 13 13 13 11 Ankyrin repeat Ank_5 PF13857.6 KZN93965.1 - 7.7e-44 147.2 19.6 7.1e-09 35.8 0.1 11.1 4 4 7 11 11 11 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 KZN93965.1 - 1.2e-43 146.9 17.1 2.8e-08 34.1 0.0 9.3 3 3 7 10 10 10 9 Ankyrin repeats (many copies) Ank PF00023.30 KZN93965.1 - 1.7e-33 113.6 26.7 1.4e-05 25.3 0.0 11.6 12 0 0 12 12 12 9 Ankyrin repeat F-box-like PF12937.7 KZN93965.1 - 0.0003 20.6 0.2 0.00056 19.8 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN93965.1 - 0.035 14.0 0.1 0.085 12.8 0.1 1.7 1 0 0 1 1 1 0 F-box domain MRP-S28 PF10213.9 KZN93967.1 - 0.0033 17.8 0.1 2.2 8.7 0.0 2.7 3 0 0 3 3 3 2 Mitochondrial ribosomal subunit protein PolyA_pol_arg_C PF12626.7 KZN93967.1 - 0.055 13.5 0.2 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 Polymerase A arginine-rich C-terminus Dimer_Tnp_hAT PF05699.14 KZN93968.1 - 3.4e-11 42.8 0.0 1e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 KZN93968.1 - 0.0024 17.9 2.7 0.0057 16.6 2.7 1.6 1 0 0 1 1 1 1 BED zinc finger RbsD_FucU PF05025.13 KZN93969.1 - 0.11 12.9 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 RbsD / FucU transport protein family Virul_fac_BrkB PF03631.15 KZN93971.1 - 0.26 10.8 0.7 0.37 10.4 0.7 1.2 1 0 0 1 1 1 0 Virulence factor BrkB Urocanase_N PF17391.2 KZN93972.1 - 0.027 14.2 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Urocanase N-terminal domain zf-C2H2 PF00096.26 KZN93973.1 - 2.5e-09 37.1 11.5 9.9e-05 22.6 2.0 2.4 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KZN93973.1 - 1.1e-05 25.6 11.7 1.7e-05 25.0 2.8 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KZN93973.1 - 0.00083 20.0 9.8 0.052 14.4 1.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KZN93973.1 - 0.039 14.3 0.7 1.7 9.0 0.1 1.8 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 KZN93973.1 - 0.063 13.4 3.4 0.71 10.0 0.3 2.0 1 1 1 2 2 2 0 Aberrant zinc-finger FOXP-CC PF16159.5 KZN93973.1 - 0.34 11.6 3.8 0.76 10.5 1.1 2.0 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-met PF12874.7 KZN93973.1 - 0.41 11.1 6.6 0.96 9.9 0.1 2.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KZN93973.1 - 0.82 10.0 5.3 1.5 9.2 0.2 2.5 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Pox_G9-A16 PF03003.16 KZN93973.1 - 1 9.1 4.0 0.7 9.6 0.5 2.0 1 1 1 2 2 2 0 Pox virus entry-fusion-complex G9/A16 ZF-HD_dimer PF04770.12 KZN93973.1 - 2.5 8.5 8.0 0.81 10.1 1.7 2.6 2 1 1 3 3 3 0 ZF-HD protein dimerisation region zf-C2H2_6 PF13912.6 KZN93973.1 - 9.8 6.3 9.6 20 5.3 2.5 2.5 2 1 0 2 2 2 0 C2H2-type zinc finger RNase_T PF00929.24 KZN93976.1 - 1.8e-11 44.8 0.0 2.6e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 KZN93976.1 - 0.00015 21.5 0.0 0.0028 17.4 0.0 2.8 2 1 0 2 2 2 1 3'-5' exonuclease DUF5051 PF16473.5 KZN93976.1 - 0.0057 16.7 0.2 0.019 15.0 0.2 1.9 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like MaoC_dehydratas PF01575.19 KZN93976.1 - 0.14 11.7 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 MaoC like domain APH PF01636.23 KZN93978.1 - 1.4e-16 61.2 0.0 3.7e-16 59.8 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Microvir_J PF04726.13 KZN93981.1 - 0.46 10.5 3.0 0.67 10.0 0.6 2.4 2 0 0 2 2 2 0 Microvirus J protein DUF4407 PF14362.6 KZN93983.1 - 0.2 11.0 5.0 0.29 10.5 5.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MAP7 PF05672.11 KZN93983.1 - 0.29 10.8 13.2 0.45 10.2 13.2 1.3 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family POTRA_TamA_1 PF17243.2 KZN93983.1 - 2.3 8.4 4.2 1.5 9.0 1.8 1.9 1 1 1 2 2 2 0 POTRA domain TamA domain 1 FUSC PF04632.12 KZN93983.1 - 5.8 5.3 7.2 7.3 5.0 7.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Glyco_hydro_61 PF03443.14 KZN93985.1 - 0.011 15.7 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 KZN93985.1 - 0.052 14.2 0.0 0.076 13.7 0.0 1.2 1 0 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading DUF4625 PF15418.6 KZN93985.1 - 0.069 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) DUF4658 PF15555.6 KZN93986.1 - 0.16 12.1 0.0 0.25 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) FxsA PF04186.13 KZN93987.1 - 0.15 12.2 2.4 1.6 8.9 0.1 2.7 2 1 1 3 3 3 0 FxsA cytoplasmic membrane protein Phage_holin_3_3 PF16083.5 KZN93987.1 - 0.25 11.5 4.4 0.66 10.1 3.2 2.3 2 1 1 3 3 3 0 LydA holin phage, holin superfamily III Patatin PF01734.22 KZN93988.1 - 6.6e-21 75.4 0.3 1.8e-20 74.0 0.3 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase zf-C3HC4_3 PF13920.6 KZN93988.1 - 2.7e-05 23.9 6.1 6.8e-05 22.6 6.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KZN93988.1 - 0.0011 18.7 5.8 0.0039 17.0 5.8 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KZN93988.1 - 0.0015 18.4 5.2 0.0055 16.6 5.3 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KZN93988.1 - 0.0093 15.9 7.2 0.027 14.4 7.2 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KZN93988.1 - 0.15 12.4 8.7 0.53 10.7 8.7 2.1 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 KZN93988.1 - 1.1 9.1 8.0 1.1 9.2 4.1 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KZN93988.1 - 4.3 7.5 11.1 1.8 8.6 4.9 3.0 2 0 0 2 2 2 0 RING-type zinc-finger SRF-TF PF00319.18 KZN93991.1 - 0.00096 18.6 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Prok-JAB PF14464.6 KZN93991.1 - 0.0019 17.9 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF1180 PF06679.12 KZN93993.1 - 6.2 7.2 7.3 9.4 6.6 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF3723 PF12520.8 KZN93994.1 - 1.6e-35 122.8 0.2 1.9e-28 99.5 0.0 2.6 3 1 0 3 3 3 2 Protein of unknown function (DUF3723) Metaviral_G PF09595.10 KZN93994.1 - 0.026 14.6 0.1 0.044 13.9 0.1 1.3 1 0 0 1 1 1 0 Metaviral_G glycoprotein DUF1129 PF06570.11 KZN93995.1 - 0.23 10.9 3.6 0.36 10.3 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Get5_C PF18514.1 KZN93997.1 - 0.12 12.1 0.1 0.46 10.3 0.0 2.0 2 0 0 2 2 2 0 Get5 C-terminal domain FUSC PF04632.12 KZN93997.1 - 0.26 9.8 5.1 0.33 9.4 5.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family BNIP3 PF06553.12 KZN93998.1 - 0.22 11.2 4.2 0.3 10.7 4.2 1.2 1 0 0 1 1 1 0 BNIP3 GPI-anchored PF10342.9 KZN94000.1 - 4.4e-20 72.2 1.1 4.4e-20 72.2 1.1 2.3 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family FSA_C PF10479.9 KZN94000.1 - 0.02 13.1 7.3 0.021 13.0 7.3 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus PI3K_1B_p101 PF10486.9 KZN94000.1 - 0.48 8.2 5.8 0.67 7.7 5.8 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TFIIF_alpha PF05793.12 KZN94000.1 - 1.1 7.8 4.9 1.5 7.3 4.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Apt1 PF10351.9 KZN94000.1 - 1.4 7.7 4.6 1.6 7.5 4.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PAP1 PF08601.10 KZN94000.1 - 3.2 7.4 15.9 5.5 6.6 15.9 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 RAP1 PF07218.11 KZN94000.1 - 3.7 5.7 11.7 4.4 5.5 11.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 KZN94000.1 - 5.9 5.3 7.9 6.4 5.2 7.9 1.1 1 0 0 1 1 1 0 Macoilin family F-box PF00646.33 KZN94001.1 - 8.1e-05 22.4 0.2 0.0003 20.6 0.2 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KZN94001.1 - 0.00012 21.9 0.1 0.0004 20.2 0.1 2.0 1 0 0 1 1 1 1 F-box-like ADH_N PF08240.12 KZN94002.1 - 1.4e-25 89.3 1.5 2.4e-25 88.5 1.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN94002.1 - 3.8e-21 75.4 0.0 6e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KZN94002.1 - 5.8e-05 22.7 0.0 9.9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KZN94002.1 - 0.00011 23.2 0.0 0.00021 22.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KZN94002.1 - 0.00052 19.9 0.2 0.0017 18.3 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated FAD_binding_3 PF01494.19 KZN94002.1 - 0.014 14.6 0.1 0.02 14.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 KZN94002.1 - 0.019 15.4 0.0 0.034 14.6 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF3295 PF11702.8 KZN94004.1 - 5.9e-177 590.0 14.1 7e-177 589.7 14.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 KZN94004.1 - 2.2e-12 46.6 1.9 6.1e-12 45.1 1.9 1.9 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) MSP1_C PF07462.11 KZN94004.1 - 0.2 10.3 0.8 0.3 9.7 0.8 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF3435 PF11917.8 KZN94007.1 - 6.4e-161 535.9 0.1 1.6e-160 534.6 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) zf-C2H2_4 PF13894.6 KZN94007.1 - 0.0024 18.5 3.3 0.018 15.8 0.4 3.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KZN94007.1 - 0.061 13.8 1.5 0.6 10.7 0.2 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Pkinase_Tyr PF07714.17 KZN94009.1 - 0.00048 19.5 0.0 0.00075 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KZN94009.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain DUF3330 PF11809.8 KZN94010.1 - 0.00097 19.2 0.1 0.0031 17.5 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3330) zf-RING_2 PF13639.6 KZN94010.1 - 0.044 14.1 12.7 0.09 13.1 12.7 1.6 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.7 KZN94010.1 - 1.4 9.2 9.8 5.6 7.3 9.8 2.0 1 1 1 2 2 2 0 RING-H2 zinc finger domain Parvo_coat PF00740.18 KZN94014.1 - 0.0065 15.2 0.0 0.008 14.9 0.0 1.1 1 0 0 1 1 1 1 Parvovirus coat protein VP2 CLASP_N PF12348.8 KZN94015.1 - 0.56 9.7 14.3 30 4.1 0.0 7.1 2 2 8 10 10 10 0 CLASP N terminal PTR2 PF00854.21 KZN94016.1 - 4.7e-27 94.8 0.6 9.5e-21 74.1 0.1 2.0 1 1 1 2 2 2 2 POT family Silic_transp PF03842.13 KZN94016.1 - 0.16 10.3 0.0 0.22 9.8 0.0 1.2 1 0 0 1 1 1 0 Silicon transporter PQ-loop PF04193.14 KZN94017.1 - 2.3e-34 117.0 9.9 3.8e-19 68.2 1.4 3.2 3 0 0 3 3 3 2 PQ loop repeat CYSTM PF12734.7 KZN94017.1 - 0.15 12.4 0.1 0.44 10.9 0.1 1.7 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance Phage_holin_Dp1 PF16938.5 KZN94017.1 - 1.4 9.2 7.9 1.8 8.8 3.8 2.7 2 1 1 3 3 3 0 Putative phage holin Dp-1 PALP PF00291.25 KZN94019.1 - 1.6e-24 86.9 0.0 1.2e-23 84.0 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Cys_Met_Meta_PP PF01053.20 KZN94020.1 - 2.6e-126 421.2 0.0 3e-126 421.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KZN94020.1 - 5.1e-10 39.1 0.0 8.2e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KZN94020.1 - 2.4e-08 33.7 0.0 4.4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KZN94020.1 - 6.2e-07 28.7 0.1 1.1e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KZN94020.1 - 0.0023 17.2 0.0 0.0045 16.3 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.16 KZN94020.1 - 0.15 10.8 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Glycine cleavage system P-protein PTR2 PF00854.21 KZN94021.1 - 2.2e-62 211.2 3.2 6.8e-62 209.6 3.2 1.7 1 1 0 1 1 1 1 POT family ATPgrasp_N PF18130.1 KZN94022.1 - 6.5e-18 65.1 0.0 1.8e-17 63.7 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 KZN94022.1 - 3.6e-14 52.7 0.0 1.4e-13 50.8 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KZN94022.1 - 0.13 11.8 0.0 1.1 8.7 0.0 2.2 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KZN94022.1 - 0.2 11.4 0.0 0.86 9.4 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon Fungal_trans PF04082.18 KZN94023.1 - 2.4e-06 26.8 0.1 3.8e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain F-box_4 PF15966.5 KZN94023.1 - 0.12 12.3 0.1 0.43 10.5 0.0 1.9 2 0 0 2 2 2 0 F-box Ank PF00023.30 KZN94024.1 - 4.8e-15 55.2 3.8 1e-05 25.7 0.6 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KZN94024.1 - 3.1e-14 51.7 0.9 5.4e-05 23.3 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 KZN94024.1 - 5e-14 52.7 0.2 3.3e-13 50.0 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KZN94024.1 - 1e-13 51.2 3.8 1.1e-05 25.6 0.3 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KZN94024.1 - 2e-10 41.0 0.9 3.3e-05 24.3 0.1 3.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) HLH PF00010.26 KZN94025.1 - 5.1e-05 23.1 0.3 9.3e-05 22.3 0.3 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF982 PF06169.12 KZN94025.1 - 0.093 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF982) Ank_2 PF12796.7 KZN94029.1 - 9.5e-18 64.6 0.4 8.5e-10 39.1 0.0 2.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KZN94029.1 - 1.1e-15 57.3 5.5 1.2e-05 25.6 0.2 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 KZN94029.1 - 2.2e-15 55.2 1.6 4.7e-06 26.5 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KZN94029.1 - 6.4e-15 55.0 6.5 1.3e-07 31.8 0.5 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KZN94029.1 - 1.2e-13 51.2 0.2 3.1e-07 30.8 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) ATPgrasp_N PF18130.1 KZN94030.1 - 4.9e-17 62.3 0.0 9.6e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 KZN94030.1 - 1.3e-10 41.1 0.0 3.9e-10 39.5 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KZN94030.1 - 0.05 13.1 0.0 0.88 9.1 0.0 2.2 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus RVT_1 PF00078.27 KZN94031.1 - 5.7e-19 68.5 0.0 9.7e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 KZN94031.1 - 1.3e-08 34.7 0.0 1.9e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KZN94031.1 - 2.2e-06 28.2 0.0 4.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KZN94031.1 - 4e-05 24.2 0.0 7.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF3975 PF13126.6 KZN94033.1 - 8.5 6.9 8.0 2.5 8.6 1.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3975) CP2 PF04516.15 KZN94036.1 - 2.3e-59 200.5 0.0 3.1e-59 200.1 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor zf-C2H2 PF00096.26 KZN94037.1 - 0.0012 19.2 10.4 0.3 11.6 2.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KZN94037.1 - 0.0018 19.0 5.8 1.1 10.3 2.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KZN94037.1 - 0.0051 17.2 0.2 0.0051 17.2 0.2 2.5 3 0 0 3 3 3 1 Zinc-finger double domain Ifi-6-16 PF06140.13 KZN94038.1 - 3.4e-08 33.3 28.0 3.4e-08 33.3 28.0 2.3 1 1 1 2 2 2 1 Interferon-induced 6-16 family H_PPase PF03030.16 KZN94039.1 - 0.081 11.5 0.4 0.11 11.1 0.4 1.1 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase NICE-1 PF15845.5 KZN94039.1 - 0.1 13.4 0.5 0.18 12.6 0.5 1.4 1 0 0 1 1 1 0 Cysteine-rich C-terminal 1 family Kdo PF06293.14 KZN94044.1 - 8.1e-05 22.1 0.1 0.00012 21.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KZN94044.1 - 0.0024 17.5 0.0 0.0038 16.8 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KZN94044.1 - 0.019 14.9 0.2 0.052 13.4 0.2 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 KZN94044.1 - 0.03 13.7 0.0 0.043 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain WaaY PF06176.11 KZN94044.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) DUF5071 PF16804.5 KZN94046.1 - 0.059 13.6 0.3 0.26 11.5 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5071) HATPase_c_3 PF13589.6 KZN94047.1 - 0.00017 21.4 0.0 0.0003 20.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CLASP_N PF12348.8 KZN94048.1 - 0.017 14.7 0.3 0.64 9.5 0.1 2.2 2 0 0 2 2 2 0 CLASP N terminal Ank_5 PF13857.6 KZN94049.1 - 6e-13 48.7 1.5 5.3e-08 33.0 0.4 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KZN94049.1 - 1.2e-12 48.3 0.1 2.2e-08 34.5 0.0 3.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 KZN94049.1 - 9.1e-11 41.7 1.1 0.00017 21.9 0.2 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KZN94049.1 - 1.7e-08 34.1 0.2 0.00011 22.4 0.1 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KZN94049.1 - 1.2e-06 28.9 0.5 0.044 14.4 0.1 3.9 2 1 2 4 4 4 2 Ankyrin repeats (many copies) PolyA_pol_arg_C PF12626.7 KZN94049.1 - 0.022 14.8 0.3 0.2 11.7 0.0 2.3 2 0 0 2 2 2 0 Polymerase A arginine-rich C-terminus DUF3330 PF11809.8 KZN94052.1 - 0.0029 17.6 0.1 0.0097 16.0 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3330) zf-RING_2 PF13639.6 KZN94052.1 - 0.011 16.1 9.5 0.023 15.0 9.5 1.6 1 0 0 1 1 1 0 Ring finger domain RINGv PF12906.7 KZN94052.1 - 0.079 13.1 10.0 0.16 12.1 10.0 1.5 1 0 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 KZN94052.1 - 0.65 9.7 7.5 1.7 8.3 7.5 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Ank_2 PF12796.7 KZN94053.1 - 4.3e-54 181.0 6.6 9.3e-12 45.4 0.0 6.2 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN94053.1 - 4.4e-43 145.1 14.7 1.7e-07 31.7 0.0 8.8 3 3 7 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN94053.1 - 9.2e-42 136.3 14.3 0.00018 21.7 0.0 13.3 13 0 0 13 13 13 11 Ankyrin repeat Ank_5 PF13857.6 KZN94053.1 - 1.6e-40 136.6 20.4 2.2e-08 34.2 0.0 11.1 3 3 7 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 KZN94053.1 - 1.9e-31 107.1 23.0 5e-05 23.6 0.0 11.5 12 0 0 12 12 12 8 Ankyrin repeat F-box-like PF12937.7 KZN94053.1 - 0.00029 20.7 0.2 0.00056 19.8 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN94053.1 - 0.032 14.1 0.1 0.085 12.8 0.1 1.8 1 0 0 1 1 1 0 F-box domain MukF_C PF17193.4 KZN94053.1 - 0.12 12.5 0.1 9.2 6.4 0.0 2.7 3 0 0 3 3 3 0 MukF C-terminal domain NEMO PF11577.8 KZN94055.1 - 0.3 11.1 6.0 0.76 9.8 6.0 1.6 1 1 0 1 1 1 0 NF-kappa-B essential modulator NEMO KxDL PF10241.9 KZN94057.1 - 0.053 13.8 0.1 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein PRKCSH-like PF12999.7 KZN94057.1 - 0.14 12.0 0.2 0.26 11.1 0.1 1.4 2 0 0 2 2 2 0 Glucosidase II beta subunit-like MAP7 PF05672.11 KZN94058.1 - 0.31 10.7 13.5 0.48 10.1 13.5 1.3 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family FUSC PF04632.12 KZN94058.1 - 5.7 5.3 7.4 7.3 5.0 7.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Glyco_hydro_61 PF03443.14 KZN94060.1 - 0.00055 19.9 0.0 0.00082 19.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4625 PF15418.6 KZN94060.1 - 0.006 16.8 0.0 0.012 15.9 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4625) LPMO_10 PF03067.15 KZN94060.1 - 0.022 15.4 0.0 0.028 15.1 0.0 1.2 1 0 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading Phage_holin_3_3 PF16083.5 KZN94063.1 - 0.093 12.9 2.4 0.48 10.6 2.6 2.1 1 1 1 2 2 2 0 LydA holin phage, holin superfamily III Patatin PF01734.22 KZN94064.1 - 5.4e-21 75.7 1.7 7e-21 75.4 0.4 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase zf-C3HC4_3 PF13920.6 KZN94064.1 - 2.5e-05 24.0 6.1 6.8e-05 22.6 6.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KZN94064.1 - 0.0011 18.8 5.8 0.0039 17.0 5.8 2.0 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KZN94064.1 - 0.0015 18.3 5.2 0.0055 16.6 5.3 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KZN94064.1 - 0.009 16.0 7.2 0.027 14.4 7.2 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KZN94064.1 - 0.15 12.4 8.7 0.53 10.7 8.7 2.1 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 KZN94064.1 - 1.2 9.0 8.0 1.1 9.2 4.1 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KZN94064.1 - 4.6 7.3 11.1 1.8 8.6 4.9 2.9 2 0 0 2 2 2 0 RING-type zinc-finger BAR_2 PF10455.9 KZN94066.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking TRAPPC-Trs85 PF12739.7 KZN94066.1 - 0.13 11.3 0.3 0.16 10.9 0.3 1.1 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit SRF-TF PF00319.18 KZN94067.1 - 0.00089 18.7 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Prok-JAB PF14464.6 KZN94067.1 - 0.0019 17.9 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF3723 PF12520.8 KZN94070.1 - 4.9e-69 233.3 0.2 4.5e-62 210.4 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF3723) Metaviral_G PF09595.10 KZN94070.1 - 0.044 13.9 0.1 0.075 13.1 0.1 1.2 1 0 0 1 1 1 0 Metaviral_G glycoprotein HlyIII PF03006.20 KZN94071.1 - 0.024 14.4 7.3 0.032 14.0 7.3 1.1 1 0 0 1 1 1 0 Haemolysin-III related IFT57 PF10498.9 KZN94073.1 - 0.0019 17.3 0.2 0.0022 17.0 0.2 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Fez1 PF06818.15 KZN94073.1 - 0.0088 16.5 1.5 0.013 15.9 1.5 1.2 1 0 0 1 1 1 1 Fez1 Spc7 PF08317.11 KZN94073.1 - 0.023 13.6 3.9 0.043 12.7 3.8 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.8 KZN94073.1 - 0.024 14.7 3.2 0.04 14.0 3.2 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 KZN94073.1 - 0.024 14.7 3.2 0.042 13.9 3.2 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prominin PF05478.11 KZN94073.1 - 0.027 12.5 0.5 0.031 12.2 0.5 1.0 1 0 0 1 1 1 0 Prominin Uso1_p115_C PF04871.13 KZN94073.1 - 0.032 14.6 3.4 0.051 14.0 3.4 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region HALZ PF02183.18 KZN94073.1 - 0.046 13.9 1.0 0.15 12.3 0.2 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF3450 PF11932.8 KZN94073.1 - 0.047 13.0 1.4 0.066 12.5 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) YabA PF06156.13 KZN94073.1 - 0.059 14.0 1.6 0.1 13.2 1.6 1.4 1 0 0 1 1 1 0 Initiation control protein YabA TPR_MLP1_2 PF07926.12 KZN94073.1 - 0.075 13.1 4.6 0.43 10.6 3.2 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein TMPIT PF07851.13 KZN94073.1 - 0.16 11.1 1.5 0.22 10.7 1.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF4200 PF13863.6 KZN94073.1 - 0.41 11.1 3.5 9.1 6.7 4.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) YscO PF07321.12 KZN94073.1 - 2.7 7.9 8.7 0.69 9.9 2.0 2.3 2 1 1 3 3 3 0 Type III secretion protein YscO FUSC PF04632.12 KZN94074.1 - 3.1 6.2 6.0 3.7 6.0 6.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family RNase_T PF00929.24 KZN94077.1 - 1.5e-12 48.4 0.0 2.1e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 KZN94077.1 - 5.2e-05 23.0 0.0 0.001 18.8 0.0 2.8 2 1 0 2 2 2 1 3'-5' exonuclease DUF5051 PF16473.5 KZN94077.1 - 0.0034 17.4 0.1 0.011 15.7 0.1 1.9 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like Kdo PF06293.14 KZN94078.1 - 5.7e-06 25.8 0.0 1.2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KZN94078.1 - 0.00064 19.2 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KZN94078.1 - 0.0055 16.7 0.1 0.0055 16.7 0.1 3.6 3 1 1 4 4 4 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN94078.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Casc1_N PF15927.5 KZN94078.1 - 0.33 10.6 17.5 0.58 9.8 17.5 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus SRF-TF PF00319.18 KZN94079.1 - 0.00098 18.6 0.1 0.0014 18.1 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Dimer_Tnp_hAT PF05699.14 KZN94080.1 - 1e-11 44.4 0.0 1.8e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-C2H2 PF00096.26 KZN94082.1 - 4.2e-09 36.4 11.6 9.9e-05 22.6 2.0 2.4 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KZN94082.1 - 1e-05 25.7 12.0 1.5e-05 25.2 3.1 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KZN94082.1 - 0.00068 20.3 9.6 0.052 14.4 1.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KZN94082.1 - 0.031 14.6 0.6 0.1 12.9 0.6 1.7 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 KZN94082.1 - 0.093 12.9 3.3 1.2 9.3 0.3 2.0 1 1 1 2 2 2 0 Aberrant zinc-finger zf-met PF12874.7 KZN94082.1 - 0.21 12.0 6.3 0.96 9.9 0.1 2.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 KZN94082.1 - 0.25 12.0 3.8 0.54 10.9 1.2 2.0 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 KZN94082.1 - 0.29 11.5 5.0 1.5 9.2 0.2 2.5 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Pox_G9-A16 PF03003.16 KZN94082.1 - 1.2 8.8 4.1 0.86 9.3 0.6 2.0 1 1 1 2 2 2 0 Pox virus entry-fusion-complex G9/A16 ZF-HD_dimer PF04770.12 KZN94082.1 - 7.3 7.0 7.9 2.4 8.6 1.7 2.6 2 1 1 3 3 3 0 ZF-HD protein dimerisation region RNase_T PF00929.24 KZN94086.1 - 1.5e-12 48.4 0.0 2.1e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 KZN94086.1 - 5.2e-05 23.0 0.0 0.001 18.8 0.0 2.8 2 1 0 2 2 2 1 3'-5' exonuclease DUF5051 PF16473.5 KZN94086.1 - 0.0034 17.4 0.1 0.011 15.7 0.1 1.9 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like Pkinase PF00069.25 KZN94088.1 - 3.2e-09 36.5 0.0 6.4e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN94088.1 - 3e-06 26.7 0.0 1.3e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KZN94088.1 - 0.0029 17.6 0.0 0.0045 16.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KZN94088.1 - 0.0096 15.3 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KZN94088.1 - 0.06 12.6 0.0 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like AAA PF00004.29 KZN94089.1 - 1.3e-19 70.9 0.6 1.3e-17 64.5 0.0 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KZN94089.1 - 0.0071 16.6 1.6 6.3 7.1 0.0 3.3 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 KZN94089.1 - 0.015 15.7 0.4 0.11 12.9 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.6 KZN94089.1 - 0.019 15.4 0.0 0.089 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KZN94089.1 - 0.032 14.8 0.1 0.11 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 KZN94089.1 - 0.064 13.4 0.0 0.25 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KZN94089.1 - 0.078 13.0 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SLATT_5 PF18160.1 KZN94090.1 - 0.6 9.4 3.4 0.23 10.8 0.7 1.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 7TM_GPCR_Srw PF10324.9 KZN94090.1 - 0.94 8.7 8.1 2.2 7.5 6.1 2.3 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw DUF3330 PF11809.8 KZN94091.1 - 0.0026 17.8 0.1 0.0082 16.2 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3330) zf-RING_2 PF13639.6 KZN94091.1 - 0.0067 16.7 8.8 0.015 15.7 8.8 1.6 1 0 0 1 1 1 1 Ring finger domain Zn_ribbon_17 PF17120.5 KZN94091.1 - 0.36 10.5 7.4 0.93 9.2 7.4 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Ank_2 PF12796.7 KZN94092.1 - 8.9e-56 186.4 6.5 6.4e-12 45.9 0.0 6.0 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN94092.1 - 3.6e-39 132.6 13.3 2.1e-07 31.3 0.0 8.6 3 3 7 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 KZN94092.1 - 1e-38 130.8 16.7 2.6e-08 34.0 0.0 10.3 4 4 6 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN94092.1 - 1.7e-38 126.2 12.7 0.00024 21.3 0.0 12.2 12 0 0 12 12 12 10 Ankyrin repeat Ank PF00023.30 KZN94092.1 - 2.6e-30 103.5 21.6 1.1e-05 25.6 0.0 10.6 11 1 0 11 11 11 8 Ankyrin repeat F-box-like PF12937.7 KZN94092.1 - 0.00027 20.8 0.2 0.00051 19.9 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN94092.1 - 0.045 13.6 1.0 0.078 12.9 0.1 1.9 2 0 0 2 2 2 0 F-box domain MIT PF04212.18 KZN94094.1 - 0.0077 16.3 0.1 0.013 15.5 0.1 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 KZN94094.1 - 0.011 15.5 0.2 0.024 14.3 0.2 1.5 1 0 0 1 1 1 0 TPR repeat TPR_1 PF00515.28 KZN94094.1 - 0.022 14.6 0.1 0.042 13.7 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 KZN94094.1 - 0.033 14.3 0.0 0.082 13.1 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 KZN94094.1 - 0.089 13.0 0.1 0.25 11.6 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 KZN94094.1 - 0.15 12.2 0.1 0.61 10.2 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Ank_2 PF12796.7 KZN94095.1 - 3e-102 335.4 5.3 1.1e-11 45.1 0.1 9.7 3 2 9 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN94095.1 - 4e-60 199.5 10.0 4.2e-08 33.6 0.0 12.7 7 5 5 13 13 13 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN94095.1 - 2.2e-58 187.3 6.5 0.0023 18.3 0.0 17.7 19 0 0 19 19 19 11 Ankyrin repeat Ank_5 PF13857.6 KZN94095.1 - 1.9e-54 181.0 17.4 5.3e-09 36.2 0.1 12.0 8 4 4 12 12 12 10 Ankyrin repeats (many copies) Ank PF00023.30 KZN94095.1 - 2.9e-54 179.2 18.5 1.1e-05 25.6 0.1 17.0 16 1 1 17 17 17 13 Ankyrin repeat MspA PF09203.11 KZN94096.1 - 2.3e-05 24.3 21.5 1.7e+02 2.0 21.5 3.6 1 1 0 1 1 1 0 MspA DUF1943 PF09172.11 KZN94096.1 - 0.00074 18.9 43.9 1.8e+04 -15.6 43.9 3.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1943) DUF4419 PF14388.6 KZN94098.1 - 3.2e-111 371.6 0.1 3.9e-111 371.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) DUF4389 PF14333.6 KZN94099.1 - 4.7 7.2 8.6 0.82 9.6 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) DUF4219 PF13961.6 KZN94101.1 - 2.2e-10 40.0 0.1 4.5e-10 39.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 KZN94101.1 - 7.2e-08 32.1 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Ses_B PF17046.5 KZN94104.1 - 0.041 13.8 0.4 0.065 13.2 0.4 1.4 1 0 0 1 1 1 0 SesB domain on fungal death-pathway protein DUF420 PF04238.12 KZN94105.1 - 0.018 15.3 1.8 0.11 12.7 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF420) HRI1 PF16815.5 KZN94106.1 - 0.053 13.2 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein HRI1 SLATT_5 PF18160.1 KZN94108.1 - 1.4 8.2 4.1 0.3 10.4 0.8 1.6 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF3330 PF11809.8 KZN94109.1 - 0.0025 17.9 0.1 0.0073 16.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3330) zf-RING_2 PF13639.6 KZN94109.1 - 0.0047 17.2 9.7 0.011 16.0 9.7 1.7 1 0 0 1 1 1 1 Ring finger domain RINGv PF12906.7 KZN94109.1 - 0.098 12.8 10.5 0.24 11.5 10.5 1.7 1 0 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 KZN94109.1 - 0.26 10.9 7.8 0.8 9.4 7.8 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Ank_2 PF12796.7 KZN94110.1 - 4.1e-58 193.9 10.1 6e-12 46.0 0.0 6.2 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KZN94110.1 - 2.3e-43 146.0 17.1 2.8e-08 34.1 0.0 9.3 3 3 7 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN94110.1 - 1.9e-42 138.4 16.9 0.00034 20.8 0.0 13.3 13 0 0 13 13 13 11 Ankyrin repeat Ank_5 PF13857.6 KZN94110.1 - 4.6e-41 138.3 21.6 2.3e-08 34.1 0.1 10.7 4 4 7 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 KZN94110.1 - 3.8e-32 109.3 27.7 1.2e-05 25.5 0.0 11.8 12 0 0 12 12 12 8 Ankyrin repeat F-box-like PF12937.7 KZN94110.1 - 0.00025 20.9 0.3 0.00048 20.0 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN94110.1 - 0.035 14.0 0.1 0.085 12.8 0.1 1.7 1 0 0 1 1 1 0 F-box domain MukF_C PF17193.4 KZN94110.1 - 0.051 13.7 0.1 11 6.2 0.0 2.7 3 0 0 3 3 3 0 MukF C-terminal domain SRF-TF PF00319.18 KZN94112.1 - 0.00091 18.7 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Prok-JAB PF14464.6 KZN94112.1 - 0.0031 17.3 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF3723 PF12520.8 KZN94115.1 - 1.4e-47 162.5 2.8 7e-26 91.0 0.0 3.6 2 1 1 3 3 3 3 Protein of unknown function (DUF3723) Metaviral_G PF09595.10 KZN94115.1 - 0.037 14.1 0.1 0.065 13.3 0.1 1.3 1 0 0 1 1 1 0 Metaviral_G glycoprotein HlyIII PF03006.20 KZN94116.1 - 0.031 14.0 7.9 0.04 13.6 7.9 1.1 1 0 0 1 1 1 0 Haemolysin-III related SPATA1_C PF15743.5 KZN94119.1 - 0.094 12.8 4.6 0.13 12.3 4.6 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus Get5_C PF18514.1 KZN94119.1 - 0.094 12.5 0.1 0.35 10.6 0.0 1.9 2 0 0 2 2 2 0 Get5 C-terminal domain RIC3 PF15361.6 KZN94119.1 - 1.5 9.2 3.8 2.3 8.6 3.8 1.3 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Methyltrans_Mon PF14314.6 KZN94120.1 - 0.068 11.2 0.5 0.083 10.9 0.5 1.0 1 0 0 1 1 1 0 Virus-capping methyltransferase DUF150_C PF17384.2 KZN94121.1 - 0.03 14.5 0.0 0.08 13.1 0.0 1.8 1 1 0 1 1 1 0 RimP C-terminal SH3 domain Ank_2 PF12796.7 KZN94122.1 - 3.6e-20 72.3 0.1 8.9e-10 39.0 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KZN94122.1 - 1.6e-10 41.0 0.3 4.7e-07 30.0 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN94122.1 - 6.4e-10 38.4 0.2 0.00039 20.7 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KZN94122.1 - 1.8e-09 37.9 0.1 1.4e-06 28.7 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KZN94122.1 - 7.9e-08 32.4 0.2 6e-05 23.3 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat LysM PF01476.20 KZN94124.1 - 3.1e-18 65.6 0.7 5.9e-06 26.2 0.1 3.2 3 0 0 3 3 3 3 LysM domain UPF0203 PF05254.12 KZN94124.1 - 0.0072 16.5 4.0 0.83 9.9 0.1 2.6 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0203) CelD_N PF02927.14 KZN94125.1 - 0.11 13.4 0.0 4 8.4 0.0 2.2 2 0 0 2 2 2 0 Cellulase N-terminal ig-like domain Glyco_hydro_18 PF00704.28 KZN94126.1 - 6.4e-46 157.5 0.1 1.3e-45 156.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Hce2 PF14856.6 KZN94126.1 - 1.2e-27 96.1 0.5 4.4e-27 94.4 0.5 2.1 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor LysM PF01476.20 KZN94126.1 - 1.9e-05 24.6 0.0 0.14 12.2 0.0 2.7 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 KZN94126.1 - 3.5e-05 24.2 8.2 3.5e-05 24.2 8.2 3.5 2 0 0 2 2 2 1 Chitin recognition protein Peptidase_C97 PF05903.14 KZN94127.1 - 0.035 13.9 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 PPPDE putative peptidase domain DUF2745 PF10922.8 KZN94128.1 - 0.009 16.3 0.1 0.013 15.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2745) Tubulin_C PF03953.17 KZN94129.1 - 2.8e-45 153.6 0.1 4.1e-45 153.0 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 KZN94129.1 - 1.4e-22 80.8 0.0 2.3e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin PF00091.25 KZN94130.1 - 4.3e-23 82.5 0.0 5.2e-23 82.3 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Abhydrolase_6 PF12697.7 KZN94131.1 - 2.1e-07 31.7 0.1 4.2e-07 30.8 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Con-6 PF10346.9 KZN94132.1 - 0.011 15.8 0.6 1.2 9.2 0.0 2.5 2 1 0 2 2 2 0 Conidiation protein 6 Bravo_FIGEY PF13882.6 KZN94133.1 - 0.11 13.9 3.4 0.19 13.1 3.4 1.5 1 0 0 1 1 1 0 Bravo-like intracellular region DUF4724 PF15852.5 KZN94133.1 - 0.37 11.3 2.7 0.56 10.7 1.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4724) BAR_2 PF10455.9 KZN94135.1 - 0.058 12.5 0.1 0.075 12.2 0.1 1.2 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Patatin PF01734.22 KZN94136.1 - 1.8e-20 74.0 0.4 6.7e-20 72.1 0.4 2.1 2 0 0 2 2 2 1 Patatin-like phospholipase zf-C3HC4_3 PF13920.6 KZN94136.1 - 2.2e-05 24.2 6.1 6.6e-05 22.7 6.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KZN94136.1 - 0.0011 18.8 5.8 0.004 17.0 5.8 2.0 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KZN94136.1 - 0.0013 18.6 5.2 0.0053 16.6 5.3 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KZN94136.1 - 0.0082 16.1 7.2 0.027 14.4 7.2 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KZN94136.1 - 0.12 12.7 8.5 0.44 10.9 8.5 2.1 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 KZN94136.1 - 0.98 9.3 8.0 1 9.2 4.1 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KZN94136.1 - 4.2 7.5 11.1 1.8 8.7 4.9 2.9 2 0 0 2 2 2 0 RING-type zinc-finger Phage_holin_3_3 PF16083.5 KZN94137.1 - 0.14 12.3 2.9 0.95 9.6 3.3 2.1 1 1 1 2 2 2 0 LydA holin phage, holin superfamily III Pkinase PF00069.25 KZN94138.1 - 2.2e-05 24.0 0.0 2.9e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN94138.1 - 0.033 13.5 0.0 0.044 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Glyco_hydro_61 PF03443.14 KZN94139.1 - 0.0056 16.6 0.0 0.0087 16.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4625 PF15418.6 KZN94139.1 - 0.012 15.9 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) DUF4407 PF14362.6 KZN94141.1 - 0.37 10.1 6.0 0.53 9.6 6.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MAP7 PF05672.11 KZN94141.1 - 0.55 9.9 14.3 0.86 9.3 14.3 1.3 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family FUSC PF04632.12 KZN94141.1 - 3 6.3 6.5 3.8 5.9 6.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family PRKCSH-like PF12999.7 KZN94142.1 - 0.1 12.4 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Glucosidase II beta subunit-like Microvir_J PF04726.13 KZN94144.1 - 0.27 11.2 4.1 0.41 10.7 0.5 2.6 2 0 0 2 2 2 0 Microvirus J protein PolyA_pol_arg_C PF12626.7 KZN94146.1 - 0.054 13.5 0.2 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 Polymerase A arginine-rich C-terminus Dimer_Tnp_hAT PF05699.14 KZN94147.1 - 4.3e-11 42.5 0.0 1.2e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 KZN94147.1 - 0.0024 17.8 2.7 0.0057 16.6 2.7 1.6 1 0 0 1 1 1 1 BED zinc finger RbsD_FucU PF05025.13 KZN94148.1 - 0.12 12.8 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 RbsD / FucU transport protein family Ferric_reduct PF01794.19 KZN94150.1 - 0.004 17.3 3.3 0.004 17.3 3.3 2.0 1 1 1 2 2 2 1 Ferric reductase like transmembrane component Virul_fac_BrkB PF03631.15 KZN94150.1 - 0.03 13.9 1.0 0.047 13.3 1.0 1.2 1 0 0 1 1 1 0 Virulence factor BrkB DUF1772 PF08592.11 KZN94150.1 - 1.6 9.1 6.8 0.65 10.3 0.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) zf-C2H2 PF00096.26 KZN94152.1 - 2.2e-07 31.0 12.8 0.00057 20.2 2.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KZN94152.1 - 8.3e-05 22.8 3.1 8.3e-05 22.8 3.1 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KZN94152.1 - 0.013 16.3 9.9 0.33 11.9 1.2 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 KZN94152.1 - 0.019 15.3 5.4 4.5 7.8 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type RasGEF PF00617.19 KZN94154.1 - 0.0018 18.5 0.0 0.0065 16.7 0.0 1.9 1 1 0 1 1 1 1 RasGEF domain Zn_clus PF00172.18 KZN94157.1 - 1.2e-08 34.9 13.1 2.2e-08 34.1 13.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.23 KZN94158.1 - 1.7e-09 38.0 3.3 6e-08 32.9 3.3 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN94158.1 - 0.00092 18.9 1.4 0.00093 18.8 0.1 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase DUF3330 PF11809.8 KZN94160.1 - 0.0027 17.7 0.1 0.0082 16.2 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3330) zf-RING_2 PF13639.6 KZN94160.1 - 0.0087 16.4 8.6 0.021 15.1 8.6 1.7 1 0 0 1 1 1 1 Ring finger domain RINGv PF12906.7 KZN94160.1 - 0.12 12.5 9.4 0.25 11.5 9.4 1.6 1 0 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 KZN94160.1 - 0.56 9.9 7.8 1.3 8.7 7.8 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Mitofilin PF09731.9 KZN94161.1 - 0.13 11.1 0.8 0.21 10.4 0.8 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein APH PF01636.23 KZN94162.1 - 2e-13 50.8 0.0 5.9e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN94162.1 - 0.041 13.5 0.1 0.073 12.7 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.20 KZN94162.1 - 0.089 12.1 0.8 0.15 11.3 0.1 1.6 2 0 0 2 2 2 0 Ecdysteroid kinase DUF1679 PF07914.11 KZN94162.1 - 0.2 10.5 0.0 0.33 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) FH2 PF02181.23 KZN94164.1 - 0.17 11.0 0.2 0.26 10.4 0.2 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain zf-C2H2_4 PF13894.6 KZN94165.1 - 0.00068 20.3 4.8 1.2 10.2 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KZN94165.1 - 0.004 17.5 10.0 0.092 13.2 0.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KZN94165.1 - 0.0089 16.4 0.4 0.0089 16.4 0.4 2.8 3 0 0 3 3 3 1 Zinc-finger double domain DUF5383 PF17355.2 KZN94166.1 - 0.12 12.7 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5383) Fungal_trans_2 PF11951.8 KZN94167.1 - 2.9e-08 32.9 0.9 4.6e-08 32.3 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN94167.1 - 2.1e-05 24.5 4.2 5.1e-05 23.3 4.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4662 PF15578.6 KZN94167.1 - 0.053 13.3 0.0 0.083 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) Asp PF00026.23 KZN94168.1 - 1e-22 81.0 0.1 3.1e-22 79.4 0.1 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KZN94168.1 - 0.00026 21.3 0.1 0.00096 19.4 0.1 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal SDP_N PF12278.8 KZN94168.1 - 0.17 12.0 0.2 0.55 10.4 0.1 1.8 2 0 0 2 2 2 0 Sex determination protein N terminal CDC45 PF02724.14 KZN94169.1 - 2.6e-26 92.1 0.0 3.1e-22 78.7 0.0 3.0 1 1 2 3 3 3 2 CDC45-like protein RR_TM4-6 PF06459.12 KZN94169.1 - 0.021 14.7 3.2 0.023 14.5 3.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Rrn6 PF10214.9 KZN94169.1 - 0.031 12.8 3.1 0.038 12.5 3.1 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Tir_receptor_N PF07490.11 KZN94169.1 - 0.16 11.8 1.1 0.29 10.9 1.1 1.4 1 1 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus NPR3 PF03666.13 KZN94169.1 - 2.3 6.9 7.2 2.8 6.6 7.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 KZN94169.1 - 3.5 6.3 6.5 4.5 5.9 6.5 1.1 1 0 0 1 1 1 0 Presenilin NARP1 PF12569.8 KZN94169.1 - 4.8 6.0 9.8 6 5.7 9.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Connexin PF00029.19 KZN94169.1 - 5.1 6.8 4.9 7.3 6.3 4.9 1.2 1 0 0 1 1 1 0 Connexin Sec62 PF03839.16 KZN94169.1 - 5.5 6.4 8.1 7.8 5.9 8.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Aquarius_N PF16399.5 KZN94169.1 - 7.9 4.4 7.3 9.5 4.1 7.3 1.0 1 0 0 1 1 1 0 Intron-binding protein aquarius N-terminus RIH_assoc PF08454.11 KZN94172.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 RyR and IP3R Homology associated DUF3632 PF12311.8 KZN94174.1 - 2.8e-05 24.6 0.0 5.7e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) Antifungal_prot PF11402.8 KZN94175.1 - 2.3e-22 79.0 19.2 2.8e-22 78.7 19.2 1.1 1 0 0 1 1 1 1 Antifungal protein DUF3632 PF12311.8 KZN94176.1 - 2.4e-29 103.0 0.0 3.5e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) BLACT_WH PF17778.1 KZN94177.1 - 0.12 12.4 0.3 0.17 11.9 0.3 1.2 1 0 0 1 1 1 0 Beta-lactamase associated winged helix domain SPX PF03105.19 KZN94178.1 - 0.11 12.3 1.9 0.13 12.1 1.9 1.1 1 0 0 1 1 1 0 SPX domain Ank_2 PF12796.7 KZN94179.1 - 3e-43 146.3 2.9 1.5e-09 38.3 0.0 5.8 1 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KZN94179.1 - 6.2e-34 112.2 12.0 0.0053 17.2 0.0 11.2 11 0 0 11 11 11 9 Ankyrin repeat Ank_4 PF13637.6 KZN94179.1 - 2e-30 104.8 12.8 3.5e-06 27.5 0.1 7.8 3 3 6 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KZN94179.1 - 1.5e-29 101.7 16.0 3.7e-06 27.1 0.0 8.9 2 2 6 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 KZN94179.1 - 1.3e-25 88.7 18.3 9.9e-06 25.8 0.0 10.0 11 0 0 11 11 11 8 Ankyrin repeat F-box-like PF12937.7 KZN94179.1 - 0.0011 18.8 0.2 0.0021 17.9 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KZN94179.1 - 0.17 11.8 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 F-box PRKCSH-like PF12999.7 KZN94183.1 - 0.088 12.6 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Glucosidase II beta subunit-like FUSC PF04632.12 KZN94184.1 - 0.25 9.8 1.6 0.26 9.8 1.6 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Acetyltransf_16 PF05301.11 KZN94184.1 - 0.39 10.5 1.6 0.55 10.0 1.6 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 MAP7 PF05672.11 KZN94184.1 - 0.58 9.8 13.2 0.79 9.4 13.2 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Phage_holin_3_3 PF16083.5 KZN94186.1 - 0.37 10.9 3.6 0.68 10.1 2.3 2.1 2 1 0 2 2 2 0 LydA holin phage, holin superfamily III Patatin PF01734.22 KZN94187.1 - 2.1e-21 77.1 1.7 2.6e-21 76.8 0.5 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase zf-C3HC4_3 PF13920.6 KZN94187.1 - 2.5e-05 24.0 6.1 6.8e-05 22.6 6.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KZN94187.1 - 0.0011 18.8 5.8 0.0039 17.0 5.8 2.0 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KZN94187.1 - 0.0015 18.3 5.2 0.0055 16.6 5.3 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KZN94187.1 - 0.009 16.0 7.2 0.027 14.4 7.2 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KZN94187.1 - 0.15 12.4 8.7 0.53 10.7 8.7 2.1 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 KZN94187.1 - 1.2 9.0 8.0 1.1 9.2 4.1 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KZN94187.1 - 4.6 7.3 11.1 1.8 8.6 4.9 2.9 2 0 0 2 2 2 0 RING-type zinc-finger RAI1 PF08652.11 KZN94188.1 - 0.094 12.9 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 RAI1 like PD-(D/E)XK nuclease SRF-TF PF00319.18 KZN94189.1 - 0.00088 18.7 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Prok-JAB PF14464.6 KZN94189.1 - 0.002 17.9 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF3723 PF12520.8 KZN94192.1 - 2.5e-31 109.0 0.0 2.1e-28 99.3 0.0 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF3723) DUF1129 PF06570.11 KZN94193.1 - 0.27 10.7 2.8 0.4 10.1 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) PMAIP1 PF15150.6 KZN94194.1 - 0.32 10.9 1.9 7 6.6 1.6 2.2 1 1 1 2 2 2 0 Phorbol-12-myristate-13-acetate-induced RexA PF15969.5 KZN94195.1 - 0.11 12.1 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Intracellular sensor of Lambda phage, Abi component KAR9 PF08580.10 KZN94196.1 - 0.042 12.4 0.0 0.046 12.3 0.0 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 SPATA1_C PF15743.5 KZN94196.1 - 0.049 13.7 4.4 0.066 13.3 4.4 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus Get5_C PF18514.1 KZN94196.1 - 0.098 12.4 0.1 0.38 10.5 0.0 1.9 2 0 0 2 2 2 0 Get5 C-terminal domain RIC3 PF15361.6 KZN94196.1 - 1.7 9.0 4.2 3.6 8.0 4.2 1.5 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Methyltrans_Mon PF14314.6 KZN94197.1 - 0.1 10.6 0.2 0.13 10.3 0.2 1.1 1 0 0 1 1 1 0 Virus-capping methyltransferase CLASP_N PF12348.8 KZN94198.1 - 0.0031 17.1 2.8 0.062 12.8 0.1 3.3 1 1 3 4 4 4 1 CLASP N terminal YqhG PF11079.8 KZN94198.1 - 0.09 11.7 0.2 0.12 11.3 0.2 1.1 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function Scytalone_dh PF02982.14 KZN94202.1 - 1.4e-17 63.9 0.1 1.8e-17 63.6 0.1 1.1 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 KZN94202.1 - 5.9e-11 42.6 0.3 7.4e-11 42.3 0.3 1.1 1 0 0 1 1 1 1 SnoaL-like domain YfkB PF08756.10 KZN94202.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.5 1 1 0 1 1 1 0 YfkB-like domain Egh16-like PF11327.8 KZN94203.1 - 3.4e-41 141.7 3.5 5.1e-41 141.1 3.5 1.3 1 1 0 1 1 1 1 Egh16-like virulence factor TPR_16 PF13432.6 KZN94206.1 - 0.00016 22.3 4.7 0.00016 22.3 4.7 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KZN94206.1 - 0.00065 19.4 2.1 0.08 12.8 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KZN94206.1 - 0.011 15.8 7.3 0.43 10.8 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KZN94206.1 - 1.1 9.9 8.4 1.7 9.2 0.4 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat MatE PF01554.18 KZN94207.1 - 9.5e-05 22.1 11.5 0.00017 21.3 2.9 3.3 2 2 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KZN94207.1 - 0.012 15.7 3.0 0.012 15.7 3.0 3.1 2 1 1 3 3 3 0 Polysaccharide biosynthesis C-terminal domain Glyco_hydro_18 PF00704.28 KZN94209.1 - 6.3e-65 220.0 0.4 9.1e-65 219.4 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KZN94209.1 - 3.7e-09 36.9 9.4 3.7e-09 36.9 9.4 5.6 8 0 0 8 8 8 2 Chitin recognition protein HEPN_Swt1 PF18731.1 KZN94209.1 - 0.12 12.7 0.2 0.28 11.5 0.2 1.6 1 0 0 1 1 1 0 Swt1-like HEPN Pectate_lyase_3 PF12708.7 KZN94210.1 - 5.1e-100 333.7 9.4 1.3e-84 283.4 4.6 2.7 2 0 0 2 2 2 2 Pectate lyase superfamily protein LysM PF01476.20 KZN94210.1 - 1.9e-11 43.9 0.1 0.00067 19.7 0.0 3.8 3 0 0 3 3 3 3 LysM domain End_N_terminal PF12218.8 KZN94210.1 - 5e-07 29.3 2.4 0.013 15.2 0.1 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Catalase-rel PF06628.12 KZN94212.1 - 8.4e-06 25.9 0.0 4.4e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Catalase-related immune-responsive F-box-like PF12937.7 KZN94212.1 - 5.6e-05 23.0 0.1 0.00014 21.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN94212.1 - 0.0062 16.4 2.8 0.016 15.1 0.9 2.4 2 0 0 2 2 2 1 F-box domain Pkinase_Tyr PF07714.17 KZN94214.1 - 0.0019 17.6 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KZN94214.1 - 0.073 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Ank_5 PF13857.6 KZN94215.1 - 0.013 15.8 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (many copies) NleF_casp_inhib PF16809.5 KZN94215.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 NleF caspase inhibitor Zn_clus PF00172.18 KZN94217.1 - 2.2e-06 27.6 9.4 4.4e-06 26.7 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Myb_DNA-bind_6 PF13921.6 KZN94218.1 - 0.00023 21.4 0.1 0.00045 20.4 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KZN94218.1 - 0.0026 17.9 0.1 0.0046 17.1 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3435 PF11917.8 KZN94220.1 - 8e-139 463.2 2.9 8e-139 463.2 2.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) Rrp44_CSD1 PF17216.3 KZN94220.1 - 0.62 9.8 1.8 1.5 8.5 1.8 1.6 1 0 0 1 1 1 0 Rrp44-like cold shock domain E1-E2_ATPase PF00122.20 KZN94221.1 - 7.7e-50 168.9 0.0 6.7e-49 165.9 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 KZN94221.1 - 3.1e-32 110.8 0.0 7.8e-10 39.1 0.0 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 KZN94221.1 - 8.6e-32 111.1 0.4 1.9e-31 110.0 0.4 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KZN94221.1 - 3.4e-05 23.7 0.3 0.00012 21.9 0.2 2.0 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KZN94221.1 - 0.0032 17.9 0.0 0.0084 16.5 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Fer2_BFD PF04324.15 KZN94221.1 - 0.24 11.8 6.7 34 4.9 0.0 5.0 6 0 0 6 6 6 0 BFD-like [2Fe-2S] binding domain DUF2247 PF10004.9 KZN94222.1 - 0.17 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) Na_Ca_ex PF01699.24 KZN94223.1 - 1.1e-33 116.3 40.8 8.9e-17 61.4 13.7 2.0 2 0 0 2 2 2 2 Sodium/calcium exchanger protein E1-E2_ATPase PF00122.20 KZN94224.1 - 2.9e-47 160.5 3.2 7.6e-47 159.2 3.2 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KZN94224.1 - 2.5e-22 80.2 0.0 4.5e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KZN94224.1 - 6.7e-06 26.5 0.6 2.9e-05 24.4 0.1 2.3 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KZN94224.1 - 0.00028 20.7 0.0 0.002 17.9 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Rhodanese PF00581.20 KZN94224.1 - 0.024 15.1 0.0 0.075 13.6 0.0 1.8 1 0 0 1 1 1 0 Rhodanese-like domain MauE PF07291.11 KZN94224.1 - 0.45 10.3 8.9 0.13 12.0 2.3 2.5 2 0 0 2 2 2 0 Methylamine utilisation protein MauE SCAMP PF04144.13 KZN94224.1 - 2.5 8.4 7.4 1.4 9.2 3.5 2.3 2 0 0 2 2 2 0 SCAMP family LMWPc PF01451.21 KZN94225.1 - 3.5e-21 76.1 0.0 6.5e-21 75.2 0.0 1.4 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase SBF PF01758.16 KZN94226.1 - 4.7e-52 176.5 10.7 4.7e-52 176.5 10.7 2.3 2 1 0 2 2 2 1 Sodium Bile acid symporter family DUF1673 PF07895.11 KZN94226.1 - 1.8 8.2 9.6 0.9 9.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) Cyclin PF08613.11 KZN94227.1 - 1e-28 100.7 0.1 2.3e-28 99.6 0.0 1.5 1 1 1 2 2 2 1 Cyclin Cyclin_N PF00134.23 KZN94227.1 - 0.00017 21.3 0.1 0.00025 20.8 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain FMN_red PF03358.15 KZN94228.1 - 1.1e-23 83.7 0.0 1.6e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase PGA2 PF07543.12 KZN94228.1 - 0.042 13.8 0.1 0.073 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 Retrotran_gag_2 PF14223.6 KZN94229.1 - 4e-18 65.4 1.1 6.5e-18 64.7 1.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 KZN94229.1 - 0.0014 18.4 0.0 0.0034 17.1 0.0 1.7 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type HeLo PF14479.6 KZN94232.1 - 1.1e-57 195.2 0.1 1.5e-57 194.8 0.1 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.17 KZN94232.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Rad10 PF03834.14 KZN94232.1 - 0.15 12.1 0.1 0.35 10.9 0.1 1.6 1 0 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) NUDIX PF00293.28 KZN94234.1 - 7.6e-06 26.0 0.2 1.7e-05 24.9 0.2 1.5 1 1 0 1 1 1 1 NUDIX domain Cecropin PF00272.19 KZN94235.1 - 1.5e-05 24.6 0.0 1.6 8.5 0.0 3.3 3 0 0 3 3 3 3 Cecropin family FNIP PF05725.12 KZN94235.1 - 0.00058 20.0 0.4 18 5.6 0.0 3.5 3 0 0 3 3 3 3 FNIP Repeat APH PF01636.23 KZN94236.1 - 6.7e-10 39.3 0.0 1.9e-09 37.8 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KZN94236.1 - 0.21 11.2 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Endosulfine PF04667.17 KZN94237.1 - 5.6e-10 39.2 0.9 1.5e-09 37.8 0.1 1.8 1 1 1 2 2 2 1 cAMP-regulated phosphoprotein/endosulfine conserved region Kdo PF06293.14 KZN94238.1 - 0.00018 20.9 0.1 0.00041 19.8 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KZN94238.1 - 0.0046 16.9 5.2 0.012 15.6 0.1 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.25 KZN94238.1 - 0.11 11.8 0.2 0.56 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain DUF3886 PF13025.6 KZN94238.1 - 0.42 10.8 10.8 1.2 9.3 10.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) EVC2_like PF12297.8 KZN94238.1 - 3.2 6.3 5.7 5.2 5.7 5.7 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein AAA PF00004.29 KZN94239.1 - 1.1e-17 64.7 0.1 3.8e-17 62.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KZN94239.1 - 8.9e-06 26.2 0.9 0.00054 20.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.6 KZN94239.1 - 0.019 15.4 0.1 0.13 12.7 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 KZN94239.1 - 0.042 13.8 0.0 0.31 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KZN94239.1 - 0.058 13.7 1.6 5.6 7.2 0.0 2.8 2 1 0 3 3 3 0 AAA domain Rnk_N PF14760.6 KZN94239.1 - 2.3 8.8 4.1 15 6.2 0.1 3.2 3 0 0 3 3 3 0 Rnk N-terminus Myb_DNA-bind_6 PF13921.6 KZN94242.1 - 0.00092 19.4 0.0 0.0022 18.2 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KZN94242.1 - 0.0012 19.0 0.0 0.0023 18.1 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Sigma70_r4_2 PF08281.12 KZN94242.1 - 0.12 12.1 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 NmrA PF05368.13 KZN94243.1 - 1.3e-13 51.1 0.1 1.8e-13 50.6 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KZN94243.1 - 0.00016 21.6 0.0 0.00026 20.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KZN94243.1 - 0.094 12.6 0.3 2.3 8.1 0.1 2.5 2 1 0 2 2 2 0 KR domain Semialdhyde_dh PF01118.24 KZN94243.1 - 0.11 12.9 0.2 0.29 11.6 0.2 1.9 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ANAPC4 PF12896.7 KZN94246.1 - 1.8e-70 236.6 1.1 2.5e-70 236.1 1.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 KZN94246.1 - 1.6e-35 121.2 0.0 5e-33 113.3 0.0 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain HpaP PF09483.10 KZN94246.1 - 0.007 16.6 0.2 0.015 15.5 0.2 1.5 1 0 0 1 1 1 1 Type III secretion protein (HpaP) WD40 PF00400.32 KZN94246.1 - 0.044 14.7 2.8 0.95 10.4 0.0 3.8 5 0 0 5 5 5 0 WD domain, G-beta repeat PPP4R2 PF09184.11 KZN94246.1 - 0.11 12.0 3.4 0.94 9.0 2.4 2.1 2 0 0 2 2 2 0 PPP4R2 IKI3 PF04762.12 KZN94246.1 - 0.14 10.1 0.0 5.2 4.9 0.0 2.2 2 0 0 2 2 2 0 IKI3 family DUF4611 PF15387.6 KZN94246.1 - 0.37 11.0 6.0 1 9.7 6.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CDC45 PF02724.14 KZN94246.1 - 0.5 8.6 3.0 0.69 8.1 3.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF5407 PF17401.2 KZN94247.1 - 0.075 13.3 0.2 0.2 12.0 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5407) VWA_2 PF13519.6 KZN94248.1 - 0.0078 16.8 0.0 0.017 15.8 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KZN94248.1 - 0.01 16.1 0.1 0.057 13.7 0.1 2.1 2 1 0 2 2 2 0 von Willebrand factor type A domain Fungal_trans_2 PF11951.8 KZN94249.1 - 5.8e-09 35.2 5.4 3.5e-07 29.4 5.4 2.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Transgly_assoc PF04226.13 KZN94249.1 - 0.012 15.8 0.0 0.052 13.8 0.0 2.1 2 0 0 2 2 2 0 Transglycosylase associated protein zinc_ribbon_2 PF13240.6 KZN94250.1 - 0.025 14.3 0.3 0.053 13.3 0.3 1.6 1 0 0 1 1 1 0 zinc-ribbon domain GFA PF04828.14 KZN94250.1 - 0.049 14.0 0.0 0.091 13.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme HLH PF00010.26 KZN94251.1 - 8.2e-09 35.3 0.0 1.3e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Maf PF02545.14 KZN94252.1 - 1e-48 165.3 0.0 1.2e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein CybS PF05328.12 KZN94253.1 - 7.1e-50 168.1 0.0 9.1e-50 167.8 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit ADH_zinc_N PF00107.26 KZN94254.1 - 2e-23 82.8 0.0 2.9e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KZN94254.1 - 2.5e-19 69.2 0.0 4.3e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KZN94254.1 - 2.2e-08 35.3 0.0 6.8e-08 33.6 0.0 1.9 2 1 1 3 3 3 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 KZN94255.1 - 7.1e-37 127.2 0.1 8.6e-37 127.0 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KZN94255.1 - 1.4e-12 48.0 0.6 4.5e-10 40.0 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KZN94255.1 - 3.5e-06 26.3 1.8 0.00014 21.1 0.0 3.1 3 1 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KZN94255.1 - 0.00021 20.7 2.7 0.00079 18.8 1.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KZN94255.1 - 0.0017 17.7 1.9 0.057 12.6 0.0 2.7 3 0 0 3 3 3 1 Thi4 family FAD_oxidored PF12831.7 KZN94255.1 - 0.0032 16.9 0.0 1.2 8.4 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Abhydrolase_6 PF12697.7 KZN94255.1 - 0.038 14.6 0.1 0.062 13.9 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DAO PF01266.24 KZN94255.1 - 0.065 12.8 3.9 5 6.6 0.0 3.6 3 1 0 4 4 4 0 FAD dependent oxidoreductase 30K_MP_C_Ter PF11330.8 KZN94255.1 - 0.2 11.0 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 C-Terminal of 30K viral movement proteins DEAD PF00270.29 KZN94256.1 - 1.3e-42 145.6 0.1 2e-42 144.9 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KZN94256.1 - 4e-18 65.8 0.2 1.5e-17 63.9 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KZN94256.1 - 0.00039 20.5 0.0 0.00067 19.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 KZN94256.1 - 0.065 12.5 0.0 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 SecA DEAD-like domain ERCC3_RAD25_C PF16203.5 KZN94256.1 - 0.093 11.9 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Adenylsucc_synt PF00709.21 KZN94257.1 - 4e-165 549.8 0.0 4.5e-165 549.6 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase KHA PF11834.8 KZN94257.1 - 0.099 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel LOR PF04525.12 KZN94258.1 - 1.8e-23 83.1 0.0 2.2e-23 82.8 0.0 1.0 1 0 0 1 1 1 1 LURP-one-related DnaJ PF00226.31 KZN94259.1 - 2.2e-21 75.8 0.7 4.6e-21 74.7 0.7 1.6 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.18 KZN94260.1 - 1.5e-26 93.0 0.0 2.7e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN94260.1 - 1e-08 35.1 11.3 1.6e-08 34.5 11.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KZN94261.1 - 2.9e-41 141.6 9.4 6.8e-30 104.2 0.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN94261.1 - 2.3e-10 39.9 5.5 2.3e-10 39.9 5.5 1.8 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 KZN94261.1 - 1.6 7.0 9.4 0.34 9.2 3.1 2.5 2 1 0 2 2 2 0 Transmembrane secretion effector GTP1_OBG PF01018.22 KZN94262.1 - 1.8e-41 141.3 2.3 4e-31 107.7 3.2 2.4 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 KZN94262.1 - 5.7e-22 77.9 0.0 1.1e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KZN94262.1 - 2.1e-08 33.9 0.1 8.2e-08 31.9 0.0 2.0 2 1 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 KZN94262.1 - 0.0047 15.9 0.0 1.4 7.9 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 KZN94262.1 - 0.0048 17.4 0.6 0.031 14.8 0.0 2.2 2 0 0 2 2 2 1 ABC transporter GTP_EFTU PF00009.27 KZN94262.1 - 0.013 15.1 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Ploopntkinase3 PF18751.1 KZN94262.1 - 0.071 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Cupin_8 PF13621.6 KZN94263.1 - 9.3e-30 104.2 0.0 2.6e-29 102.7 0.0 1.7 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KZN94263.1 - 3.9e-05 23.3 0.1 0.0091 15.5 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 KZN94263.1 - 0.06 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 JmjC domain, hydroxylase SBD_N PF07005.11 KZN94264.1 - 1.4e-59 201.6 0.0 2.4e-59 200.8 0.0 1.4 1 0 0 1 1 1 1 Sugar-binding N-terminal domain NBD_C PF17042.5 KZN94264.1 - 3.9e-41 141.4 3.6 4.9e-41 141.1 2.4 1.8 2 0 0 2 2 2 1 Nucleotide-binding C-terminal domain CDC45 PF02724.14 KZN94265.1 - 1.7e-244 812.9 4.3 6.1e-243 807.8 4.3 3.0 1 1 0 1 1 1 1 CDC45-like protein Cwf_Cwc_15 PF04889.12 KZN94265.1 - 0.0042 16.9 8.3 0.0042 16.9 8.3 2.3 2 0 0 2 2 2 2 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 KZN94265.1 - 0.02 14.2 32.2 0.03 13.7 16.0 2.2 2 0 0 2 2 2 0 BUD22 Tir_receptor_N PF07490.11 KZN94265.1 - 0.026 14.4 1.1 0.065 13.1 1.1 1.6 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus Nop14 PF04147.12 KZN94265.1 - 0.48 8.6 25.5 0.23 9.6 10.7 2.1 2 0 0 2 2 2 0 Nop14-like family DUF5421 PF17458.2 KZN94265.1 - 1.5 8.2 8.5 2.7 7.3 8.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5421) DDHD PF02862.17 KZN94265.1 - 1.9 8.6 6.4 0.42 10.7 0.5 2.1 2 0 0 2 2 2 0 DDHD domain SDA1 PF05285.12 KZN94265.1 - 3.3 7.1 28.3 2.7 7.3 5.7 2.1 2 0 0 2 2 2 0 SDA1 FAM60A PF15396.6 KZN94265.1 - 5 7.1 13.7 0.051 13.6 4.2 2.0 2 0 0 2 2 2 0 Protein Family FAM60A RR_TM4-6 PF06459.12 KZN94265.1 - 5.1 6.8 18.1 0.17 11.7 8.7 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Peptidase_C13 PF01650.18 KZN94266.1 - 7.4e-40 137.1 0.1 1e-39 136.6 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family Ccdc124 PF06244.12 KZN94267.1 - 9.2e-30 103.8 26.5 2.3e-28 99.3 26.5 2.4 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 WD40 PF00400.32 KZN94268.1 - 2.1e-14 53.7 16.3 0.0035 18.1 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat 2OG-FeII_Oxy_2 PF13532.6 KZN94270.1 - 2.2e-38 132.4 0.3 2.9e-38 132.0 0.3 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 KZN94270.1 - 0.00048 20.2 6.0 0.00048 20.2 6.0 1.9 2 0 0 2 2 2 1 GRF zinc finger DGF-1_C PF11040.8 KZN94270.1 - 0.026 14.5 2.0 0.14 12.2 0.2 2.4 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus CUE PF02845.16 KZN94270.1 - 0.032 14.0 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 CUE domain DMA PF03474.14 KZN94270.1 - 0.12 12.0 0.1 0.3 10.7 0.0 1.6 2 0 0 2 2 2 0 DMRTA motif GMC_oxred_N PF00732.19 KZN94271.1 - 2.1e-63 214.5 0.0 3e-63 213.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KZN94271.1 - 6.3e-34 117.6 0.1 1.1e-33 116.8 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KZN94271.1 - 4.4e-06 26.0 0.0 0.019 14.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KZN94271.1 - 3.9e-05 23.4 0.0 0.044 13.4 0.0 3.0 3 1 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 KZN94271.1 - 0.0031 16.8 0.2 0.015 14.5 0.0 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KZN94271.1 - 0.0076 16.5 0.1 0.02 15.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KZN94271.1 - 0.0078 15.3 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KZN94271.1 - 0.018 14.3 0.9 0.8 8.9 0.1 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KZN94271.1 - 0.049 12.3 0.0 0.12 11.0 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 KZN94271.1 - 0.13 11.3 0.6 12 4.8 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A UQ_con PF00179.26 KZN94272.1 - 1.2e-10 41.1 0.0 2e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Asp_Glu_race PF01177.22 KZN94273.1 - 1.2e-42 146.3 0.7 1.3e-42 146.2 0.7 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase PNISR PF15996.5 KZN94273.1 - 0.082 13.2 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Fungal_trans_2 PF11951.8 KZN94275.1 - 1.2e-32 113.2 7.4 2.6e-32 112.1 7.4 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.28 KZN94276.1 - 7.4e-77 258.7 0.0 1.2e-76 258.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KZN94276.1 - 3.9e-56 190.1 0.0 5.9e-56 189.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KZN94276.1 - 5.1e-12 46.0 0.2 1e-11 45.0 0.2 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KZN94276.1 - 5.5e-07 28.9 0.0 3.1e-06 26.4 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KZN94276.1 - 4.1e-05 23.2 0.0 0.00014 21.5 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KZN94276.1 - 0.018 14.4 0.0 0.074 12.4 0.0 1.9 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KZN94277.1 - 1.2e-36 126.5 0.0 2.3e-36 125.5 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KZN94277.1 - 1.5e-15 57.6 0.0 2.2e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KZN94277.1 - 0.0028 17.1 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 KZN94277.1 - 0.14 12.7 0.1 0.34 11.5 0.1 1.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent p450 PF00067.22 KZN94278.1 - 1.6e-68 231.5 0.0 2e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sulfotransfer_4 PF17784.1 KZN94279.1 - 3e-63 213.5 0.0 3.7e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KZN94279.1 - 0.0069 16.8 0.2 1.2 9.5 0.0 2.7 1 1 0 2 2 2 2 Sulfotransferase family Methyltransf_25 PF13649.6 KZN94280.1 - 4.8e-10 40.0 0.0 1.4e-09 38.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN94280.1 - 3.4e-09 37.3 0.0 7.5e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN94280.1 - 2.3e-07 30.7 0.0 3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN94280.1 - 4.3e-06 27.3 0.0 1.5e-05 25.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN94280.1 - 0.00029 20.7 0.0 0.00051 19.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KZN94280.1 - 0.0012 18.2 0.0 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CmcI PF04989.12 KZN94280.1 - 0.046 13.4 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase MFS_1 PF07690.16 KZN94281.1 - 1.3e-21 76.9 27.6 9.1e-13 47.8 3.7 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 KZN94281.1 - 0.00018 20.2 7.5 0.051 12.1 1.1 2.1 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 KZN94281.1 - 0.0059 15.5 3.4 0.015 14.2 0.6 2.2 1 1 0 2 2 2 1 MFS_1 like family DUF3043 PF11241.8 KZN94281.1 - 0.046 13.8 0.2 1.9 8.5 0.0 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF3043) AzlD PF05437.12 KZN94281.1 - 0.11 12.6 4.7 0.75 10.0 1.6 2.8 1 1 1 2 2 2 0 Branched-chain amino acid transport protein (AzlD) Sugar_tr PF00083.24 KZN94282.1 - 5e-69 233.3 23.0 5.7e-69 233.1 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN94282.1 - 3.3e-09 36.2 31.3 3.3e-09 36.2 31.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KZN94282.1 - 0.054 12.4 13.5 0.049 12.5 7.1 2.4 2 0 0 2 2 2 0 MFS_1 like family Ribonuc_L-PSP PF01042.21 KZN94283.1 - 7.3e-36 122.8 0.0 8.1e-36 122.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Peptidase_S13 PF02113.15 KZN94283.1 - 0.11 11.2 0.0 0.12 11.0 0.0 1.0 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family Pkinase PF00069.25 KZN94284.1 - 1.2e-26 93.7 0.0 2e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN94284.1 - 3.4e-12 46.2 0.0 1.1e-11 44.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Fungal_trans_2 PF11951.8 KZN94284.1 - 1e-10 41.0 1.9 1.8e-10 40.2 1.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN94284.1 - 3.6e-08 33.4 11.1 3.6e-08 33.4 11.1 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_ser-thr_kin PF05445.11 KZN94284.1 - 0.058 12.4 0.0 0.086 11.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 KZN94284.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family CN_hydrolase PF00795.22 KZN94285.1 - 2e-56 191.2 0.0 2.3e-56 191.0 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PA PF02225.22 KZN94285.1 - 0.022 14.8 0.1 1.5 8.9 0.1 2.4 2 0 0 2 2 2 0 PA domain PALP PF00291.25 KZN94286.1 - 2e-61 208.0 0.2 2.4e-61 207.7 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme D-ser_dehydrat PF14031.6 KZN94287.1 - 1e-21 77.4 0.1 5.6e-21 75.0 0.0 2.2 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KZN94287.1 - 3.7e-12 46.4 0.1 5.3e-12 45.9 0.1 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Zn_clus PF00172.18 KZN94288.1 - 5e-08 32.9 10.8 1.4e-07 31.5 10.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KZN94288.1 - 2.9e-06 26.4 0.1 4.5e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2524 PF10732.9 KZN94288.1 - 0.15 12.4 0.1 0.3 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) Cutinase PF01083.22 KZN94289.1 - 1e-21 77.7 0.6 1.6e-21 77.1 0.6 1.3 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KZN94289.1 - 0.00027 20.6 0.1 0.00036 20.1 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain Thioesterase PF00975.20 KZN94289.1 - 0.00058 20.1 0.0 0.0012 19.1 0.0 1.5 2 0 0 2 2 2 1 Thioesterase domain DUF726 PF05277.12 KZN94289.1 - 0.021 13.7 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) MFS_1 PF07690.16 KZN94290.1 - 9.6e-10 37.9 45.5 4.4e-08 32.5 19.7 3.3 1 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN94290.1 - 2.7e-07 29.8 11.9 2.7e-07 29.8 11.9 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter Glyco_hydro_3_C PF01915.22 KZN94291.1 - 2.5e-18 66.8 0.0 1.2e-12 48.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Sugar_tr PF00083.24 KZN94292.1 - 5.2e-97 325.6 26.4 5.8e-97 325.4 26.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN94292.1 - 6.2e-33 114.2 47.0 3.5e-28 98.5 25.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KZN94292.1 - 8.6e-07 27.8 1.4 8.6e-07 27.8 1.4 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Homeobox_KN PF05920.11 KZN94293.1 - 6.5e-16 58.0 2.5 1.4e-15 56.9 2.5 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KZN94293.1 - 4e-08 33.0 0.1 9.1e-08 31.8 0.1 1.6 1 0 0 1 1 1 1 Homeodomain zf-C2H2 PF00096.26 KZN94293.1 - 3.9e-05 23.9 11.7 0.14 12.7 1.1 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type HTH_Tnp_Tc5 PF03221.16 KZN94293.1 - 0.0008 19.4 0.2 0.0033 17.4 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain zf-C2H2_4 PF13894.6 KZN94293.1 - 0.0037 18.0 1.0 0.0037 18.0 1.0 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger Cu-oxidase_3 PF07732.15 KZN94294.1 - 2e-34 118.2 1.1 2.8e-33 114.4 0.1 3.1 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KZN94294.1 - 3.7e-29 101.2 6.4 1.2e-23 83.4 1.0 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KZN94294.1 - 2.7e-14 53.6 0.0 9.6e-13 48.5 0.0 2.9 2 1 0 2 2 2 1 Multicopper oxidase Thioredoxin PF00085.20 KZN94295.1 - 2.5e-27 94.9 0.1 3e-27 94.6 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KZN94295.1 - 4.6e-06 26.9 0.1 1.3e-05 25.4 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KZN94295.1 - 1e-05 25.9 0.5 2.9e-05 24.5 0.5 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KZN94295.1 - 4.4e-05 23.0 0.0 5.1e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Phosducin PF02114.16 KZN94295.1 - 7.5e-05 21.8 0.0 8.3e-05 21.6 0.0 1.0 1 0 0 1 1 1 1 Phosducin AhpC-TSA PF00578.21 KZN94295.1 - 0.00061 19.7 0.0 0.00067 19.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 KZN94295.1 - 0.0029 17.8 0.0 0.0033 17.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 KZN94295.1 - 0.016 15.0 0.0 0.019 14.8 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 KZN94295.1 - 0.025 14.8 0.6 1 9.5 0.5 2.0 1 1 1 2 2 2 0 Thioredoxin CSN7a_helixI PF18392.1 KZN94295.1 - 0.11 12.4 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain RRM_1 PF00076.22 KZN94296.1 - 3.2e-23 81.3 0.1 4.3e-23 80.9 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KZN94296.1 - 0.0017 18.4 0.0 0.0031 17.6 0.0 1.3 1 1 0 1 1 1 1 RNA recognition motif TLP1_add_C PF18313.1 KZN94296.1 - 0.086 12.8 0.2 0.15 12.0 0.2 1.4 1 0 0 1 1 1 0 Thiolase-like protein type 1 additional C-terminal domain PAP_PilO PF06864.12 KZN94296.1 - 0.21 10.4 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) Fungal_trans PF04082.18 KZN94297.1 - 9.1e-22 77.4 0.1 3e-20 72.4 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN94297.1 - 4.6e-07 29.9 7.0 7.9e-07 29.1 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Flavin_Reduct PF01613.18 KZN94298.1 - 3e-18 66.4 0.0 4.1e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Abhydrolase_1 PF00561.20 KZN94299.1 - 2.1e-12 47.2 0.0 2e-11 44.0 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KZN94299.1 - 0.00085 18.7 0.0 0.0019 17.5 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KZN94299.1 - 0.0014 19.3 0.0 0.0018 18.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KZN94299.1 - 0.023 14.2 0.0 0.24 10.9 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family PAP_central PF04928.17 KZN94300.1 - 3.6e-110 366.8 0.0 5.2e-110 366.3 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KZN94300.1 - 1.3e-60 203.9 0.0 2e-60 203.3 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KZN94300.1 - 3.3e-11 43.3 0.0 7e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 KZN94300.1 - 0.1 12.4 0.6 0.26 11.0 0.1 1.9 2 0 0 2 2 2 0 Nrap protein PAP/OAS-like domain SQHop_cyclase_C PF13243.6 KZN94301.1 - 2.6e-43 148.3 0.0 8.2e-40 136.9 0.0 2.7 2 1 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 KZN94301.1 - 4e-30 103.2 3.3 1.1e-09 37.8 0.1 4.0 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KZN94301.1 - 2.4e-26 92.5 0.0 1.8e-20 73.2 0.0 3.9 3 2 1 4 4 4 3 Squalene-hopene cyclase N-terminal domain TED_complement PF07678.14 KZN94301.1 - 9.8e-05 21.5 0.0 0.00022 20.4 0.0 1.5 1 0 0 1 1 1 1 A-macroglobulin TED domain Pec_lyase PF09492.10 KZN94301.1 - 0.00057 19.3 0.2 0.15 11.4 0.0 3.2 2 2 0 3 3 3 1 Pectic acid lyase Mago-bind PF09282.10 KZN94301.1 - 0.17 11.8 0.1 0.54 10.2 0.0 1.9 2 0 0 2 2 2 0 Mago binding Abhydrolase_6 PF12697.7 KZN94302.1 - 4.2e-13 50.4 0.1 7.1e-13 49.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KZN94302.1 - 7.7e-07 29.0 0.0 8.8e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KZN94302.1 - 8.1e-07 28.6 0.0 1.5e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PAF-AH_p_II PF03403.13 KZN94302.1 - 0.07 11.6 0.0 0.093 11.2 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KZN94302.1 - 0.11 11.4 0.0 1.8 7.4 0.0 2.0 2 0 0 2 2 2 0 Chlorophyllase enzyme Ldi PF18566.1 KZN94303.1 - 1.1e-97 327.4 0.0 6.2e-61 206.6 0.0 2.1 1 1 1 2 2 2 2 Linalool dehydratase/isomerase Fungal_trans PF04082.18 KZN94304.1 - 1e-22 80.5 0.1 1.8e-22 79.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN94304.1 - 4.3e-07 29.9 12.1 1.1e-06 28.6 12.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.24 KZN94305.1 - 3.6e-32 111.6 2.0 5.4e-32 111.1 2.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KZN94305.1 - 5.1e-18 65.1 0.2 8.7e-18 64.3 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KZN94305.1 - 2.6e-09 37.5 1.1 2.6e-09 37.5 1.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KZN94305.1 - 0.0016 19.1 0.0 0.0081 16.8 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain FMO-like PF00743.19 KZN94306.1 - 5e-13 48.3 0.1 6e-12 44.8 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KZN94306.1 - 8.1e-13 48.4 0.0 2.3e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KZN94306.1 - 0.0001 21.6 0.0 0.0048 16.1 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KZN94306.1 - 0.00056 19.6 0.0 0.011 15.4 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KZN94306.1 - 0.00084 19.4 0.0 0.0067 16.4 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KZN94306.1 - 0.0016 17.8 0.0 0.023 13.9 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KZN94306.1 - 0.043 13.1 0.0 0.35 10.1 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 KZN94306.1 - 0.055 12.7 0.0 0.9 8.7 0.0 2.4 2 0 0 2 2 2 0 Thi4 family mRNA_cap_C PF03919.15 KZN94306.1 - 0.084 13.5 0.2 0.29 11.8 0.2 1.9 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain AMP-binding PF00501.28 KZN94307.1 - 6.3e-78 262.3 0.0 8e-78 261.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KZN94307.1 - 8.1e-13 49.2 0.0 1.9e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.21 KZN94308.1 - 0.0051 16.3 0.0 0.012 15.1 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KZN94308.1 - 0.036 13.2 0.0 4.4 6.4 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein COesterase PF00135.28 KZN94309.1 - 3.6e-09 36.0 0.0 4.6e-09 35.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family DUF3237 PF11578.8 KZN94310.1 - 2e-19 69.9 0.0 2.2e-19 69.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) KH_1 PF00013.29 KZN94310.1 - 0.11 12.3 0.4 0.88 9.4 0.1 2.1 1 1 1 2 2 2 0 KH domain ADH_zinc_N PF00107.26 KZN94311.1 - 8e-17 61.4 0.2 1.1e-16 60.9 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KZN94311.1 - 0.0025 17.3 0.1 0.0039 16.7 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KZN94311.1 - 0.009 15.3 0.2 0.014 14.7 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain EGF_alliinase PF04863.13 KZN94311.1 - 0.087 13.2 1.6 6.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Alliinase EGF-like domain Nairovirus_M PF07948.11 KZN94311.1 - 0.12 10.6 0.1 0.23 9.6 0.1 1.4 1 0 0 1 1 1 0 Nairovirus M polyprotein-like Mito_carr PF00153.27 KZN94312.1 - 7.1e-46 154.1 7.8 4.5e-17 61.8 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Spore_YtrH PF14034.6 KZN94312.1 - 0.064 13.4 1.0 0.6 10.3 0.9 2.6 2 1 0 2 2 2 0 Sporulation protein YtrH DUF3632 PF12311.8 KZN94313.1 - 4.1e-39 134.8 1.0 5.1e-39 134.5 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Alpha-amylase PF00128.24 KZN94314.1 - 7.7e-17 61.9 5.8 1.9e-16 60.6 2.2 2.5 1 1 1 2 2 2 2 Alpha amylase, catalytic domain MFS_1 PF07690.16 KZN94315.1 - 4.5e-37 127.8 35.8 4.5e-37 127.8 35.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN94315.1 - 6.6e-15 54.9 8.8 6.6e-15 54.9 8.8 2.2 2 2 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KZN94315.1 - 9.8e-06 24.3 2.3 9.8e-06 24.3 2.3 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Fungal_lectin_2 PF18647.1 KZN94315.1 - 0.076 13.5 0.0 9.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Alpha-galactosyl-binding fungal lectin Colicin_im PF03857.13 KZN94315.1 - 0.2 11.6 4.1 4.4 7.3 0.9 2.5 2 0 0 2 2 2 0 Colicin immunity protein DUF3445 PF11927.8 KZN94316.1 - 6.7e-69 231.9 0.0 7.9e-69 231.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) 4HBT_3 PF13622.6 KZN94317.1 - 8.2e-79 265.4 0.0 9.7e-79 265.1 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KZN94317.1 - 1.6e-23 83.0 0.0 5.4e-12 45.7 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase DUF4277 PF14104.6 KZN94317.1 - 0.085 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4277) SRP54_N PF02881.19 KZN94317.1 - 0.14 12.4 0.4 1.5 9.1 0.5 2.2 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain Succ_CoA_lig PF13607.6 KZN94317.1 - 0.18 11.6 0.0 1.9 8.3 0.0 2.1 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain DUF5090 PF17009.5 KZN94318.1 - 0.027 14.4 3.5 0.035 14.1 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) Amidase PF01425.21 KZN94319.1 - 3.2e-36 125.3 0.4 1.7e-33 116.3 0.3 2.1 2 0 0 2 2 2 2 Amidase MHYT PF03707.16 KZN94320.1 - 0.026 14.7 0.7 0.026 14.7 0.7 1.7 2 1 0 2 2 2 0 Bacterial signalling protein N terminal repeat Fungal_trans PF04082.18 KZN94321.1 - 9.8e-21 74.0 0.0 1.7e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN94321.1 - 1.6e-05 24.9 14.8 3.6e-05 23.8 14.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tmemb_cc2 PF10267.9 KZN94321.1 - 0.011 14.9 0.4 0.017 14.3 0.4 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein PAC4 PF16093.5 KZN94322.1 - 3.1e-26 91.4 0.1 4.4e-26 90.9 0.1 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 N2227 PF07942.12 KZN94323.1 - 8.7e-91 303.9 0.0 1.1e-90 303.5 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 KZN94323.1 - 0.0058 17.3 0.0 0.033 14.9 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN94323.1 - 0.0091 15.9 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN94323.1 - 0.0097 16.5 0.0 0.028 15.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN94323.1 - 0.15 11.8 0.0 0.76 9.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain HSP70 PF00012.20 KZN94324.1 - 5.2e-10 38.1 0.3 1.2e-08 33.7 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KZN94324.1 - 0.061 12.1 0.1 0.3 9.8 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein Prefoldin_2 PF01920.20 KZN94325.1 - 8.1e-24 83.6 4.2 1e-23 83.3 4.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit AKNA PF12443.8 KZN94325.1 - 0.024 15.3 1.3 0.032 14.9 0.1 1.8 1 1 1 2 2 2 0 AT-hook-containing transcription factor DUF5065 PF16723.5 KZN94325.1 - 0.13 12.3 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5065) DUF4795 PF16043.5 KZN94325.1 - 0.36 10.4 7.3 0.45 10.1 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) GPS2_interact PF15784.5 KZN94325.1 - 0.42 11.1 5.5 0.71 10.3 0.0 2.2 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain DivIC PF04977.15 KZN94325.1 - 0.53 10.1 9.3 6.8 6.5 5.2 2.2 2 0 0 2 2 2 0 Septum formation initiator GAS PF13851.6 KZN94325.1 - 0.61 9.4 10.5 7.2 5.9 8.4 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ATG27 PF09451.10 KZN94326.1 - 6.4e-91 304.9 0.0 7.5e-91 304.6 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 KZN94326.1 - 1.6e-05 25.0 0.2 0.014 15.5 0.2 2.6 3 0 0 3 3 3 2 Cation-independent mannose-6-phosphate receptor repeat PD40 PF07676.12 KZN94327.1 - 2.8e-46 154.6 30.7 5e-09 35.9 0.5 9.6 9 0 0 9 9 9 9 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 KZN94327.1 - 2.1e-09 36.6 5.5 0.076 11.8 0.2 6.9 4 2 2 6 6 6 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF5050 PF16472.5 KZN94327.1 - 1e-06 28.2 0.0 0.0032 16.7 0.0 3.9 4 1 0 4 4 4 2 Domain of unknown function (DUF5050) DUF3748 PF12566.8 KZN94327.1 - 0.00072 19.5 0.7 14 5.6 0.0 4.5 4 0 0 4 4 4 2 Protein of unknown function (DUF3748) WD40 PF00400.32 KZN94327.1 - 0.0092 16.8 7.1 15 6.6 0.2 5.6 6 1 0 6 6 6 1 WD domain, G-beta repeat Sulfotransfer_3 PF13469.6 KZN94328.1 - 0.012 16.0 1.4 1.9 8.8 0.1 3.1 3 1 0 3 3 3 0 Sulfotransferase family UCMA PF17085.5 KZN94328.1 - 0.087 12.8 2.1 1.5 8.8 0.1 2.6 2 1 1 3 3 3 0 Unique cartilage matrix associated protein AAA_2 PF07724.14 KZN94329.1 - 1.2e-45 155.7 0.0 2.4e-44 151.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KZN94329.1 - 1.6e-33 114.7 1.7 1.6e-33 114.7 1.7 3.1 3 0 0 3 3 3 1 AAA lid domain AAA PF00004.29 KZN94329.1 - 5.8e-27 94.7 0.0 1.4e-14 54.6 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KZN94329.1 - 5.2e-24 84.1 0.4 1.6e-23 82.6 0.4 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KZN94329.1 - 6.9e-15 55.3 0.0 5e-09 36.3 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KZN94329.1 - 4.2e-13 49.7 0.0 6.7e-05 23.2 0.0 4.4 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 KZN94329.1 - 5.6e-11 43.1 11.1 9.3e-07 29.4 0.0 5.2 6 1 1 7 7 4 2 AAA ATPase domain Sigma54_activat PF00158.26 KZN94329.1 - 1.3e-08 34.7 0.0 5e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 KZN94329.1 - 1.1e-06 28.5 0.0 0.1 12.3 0.0 3.3 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_14 PF13173.6 KZN94329.1 - 2.2e-06 27.7 0.0 0.053 13.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KZN94329.1 - 2.3e-06 28.2 0.0 0.064 13.8 0.0 3.6 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 KZN94329.1 - 3.4e-06 26.7 0.0 0.015 14.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 KZN94329.1 - 7.1e-06 26.1 0.3 0.11 12.3 0.3 4.0 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea TniB PF05621.11 KZN94329.1 - 8.6e-06 25.3 0.2 0.071 12.5 0.0 4.4 4 1 0 4 4 4 1 Bacterial TniB protein Mg_chelatase PF01078.21 KZN94329.1 - 1.6e-05 24.4 0.0 0.2 11.0 0.0 3.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KZN94329.1 - 1.9e-05 24.9 0.1 0.27 11.4 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KZN94329.1 - 4.5e-05 23.8 0.3 0.61 10.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 KZN94329.1 - 7e-05 23.2 0.0 0.56 10.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.27 KZN94329.1 - 0.00017 22.1 1.4 0.57 10.7 0.0 3.7 4 0 0 4 4 3 1 ABC transporter RuvB_N PF05496.12 KZN94329.1 - 0.00021 21.1 1.0 3.1 7.5 0.9 4.3 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 KZN94329.1 - 0.00021 21.1 0.0 1.3 8.7 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_3 PF07726.11 KZN94329.1 - 0.00033 20.5 0.0 1 9.2 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KZN94329.1 - 0.00039 20.4 0.0 0.33 11.0 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 KZN94329.1 - 0.00048 20.1 0.2 0.59 10.0 0.0 2.9 3 0 0 3 3 2 1 RsgA GTPase AAA_24 PF13479.6 KZN94329.1 - 0.00085 19.1 0.0 0.71 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KZN94329.1 - 0.0014 18.4 0.0 1.3 8.9 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SSE PF00437.20 KZN94329.1 - 0.0023 17.1 0.6 0.022 13.8 0.1 2.6 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.6 KZN94329.1 - 0.0024 18.2 0.1 0.59 10.5 0.1 3.1 2 1 0 2 2 2 1 AAA domain Roc PF08477.13 KZN94329.1 - 0.0034 17.6 0.0 1 9.6 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 KZN94329.1 - 0.0058 16.2 0.1 0.9 9.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KZN94329.1 - 0.0076 16.2 0.0 0.5 10.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain NTPase_1 PF03266.15 KZN94329.1 - 0.011 15.7 0.0 0.3 11.0 0.0 2.9 3 0 0 3 3 3 0 NTPase AAA_23 PF13476.6 KZN94329.1 - 0.012 16.2 9.9 0.53 10.7 0.0 4.2 4 1 0 4 4 4 0 AAA domain SRP54 PF00448.22 KZN94329.1 - 0.02 14.6 0.1 7.9 6.1 0.0 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Clp_N PF02861.20 KZN94329.1 - 0.057 13.5 0.1 3.3 7.9 0.0 3.5 3 0 0 3 3 3 0 Clp amino terminal domain, pathogenicity island component Rad17 PF03215.15 KZN94329.1 - 0.082 12.8 0.0 13 5.6 0.0 2.7 2 0 0 2 2 2 0 Rad17 P-loop domain Torsin PF06309.11 KZN94329.1 - 0.084 13.0 0.0 0.41 10.8 0.0 2.0 2 0 0 2 2 1 0 Torsin ResIII PF04851.15 KZN94329.1 - 0.094 12.7 0.0 15 5.6 0.0 3.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Rossmann-like PF10727.9 KZN94329.1 - 0.15 12.0 0.3 11 5.8 0.0 2.6 2 0 0 2 2 2 0 Rossmann-like domain V_ATPase_I PF01496.19 KZN94329.1 - 1.7 6.5 4.1 2.4 6.0 4.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Macoilin PF09726.9 KZN94329.1 - 3.8 5.9 8.2 5.6 5.4 8.2 1.2 1 0 0 1 1 1 0 Macoilin family Ank_2 PF12796.7 KZN94330.1 - 2.2e-20 73.0 0.2 2.2e-12 47.4 0.0 3.5 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) HET PF06985.11 KZN94330.1 - 5.6e-15 56.0 0.0 1.3e-14 54.8 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_4 PF13637.6 KZN94330.1 - 6.5e-15 55.3 0.2 6.1e-06 26.7 0.0 4.7 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KZN94330.1 - 1.2e-08 34.5 0.0 0.33 11.6 0.0 5.4 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 KZN94330.1 - 7.1e-08 32.6 0.7 0.45 10.9 0.0 5.2 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KZN94330.1 - 1.2e-05 25.5 0.5 2.9 8.5 0.0 5.1 6 0 0 6 6 6 1 Ankyrin repeat DUF2721 PF11026.8 KZN94331.1 - 0.062 13.2 6.7 1.5 8.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) EMC3_TMCO1 PF01956.16 KZN94331.1 - 0.83 9.4 5.4 12 5.6 1.6 2.6 2 1 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like AA_permease_2 PF13520.6 KZN94332.1 - 3.5e-43 148.0 51.0 4.5e-43 147.7 51.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KZN94332.1 - 3.9e-15 55.4 42.2 6.6e-15 54.7 42.2 1.3 1 0 0 1 1 1 1 Amino acid permease SNF2_N PF00176.23 KZN94333.1 - 1.5e-55 188.3 0.0 2.2e-55 187.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KZN94333.1 - 1.7e-15 57.3 0.0 3.2e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KZN94333.1 - 1.3e-09 38.3 0.0 2.3e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KZN94333.1 - 0.0011 18.8 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KZN94333.1 - 0.012 14.8 0.0 0.03 13.5 0.0 1.5 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 KZN94333.1 - 0.074 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase RPN13_C PF16550.5 KZN94333.1 - 0.1 12.8 0.3 0.68 10.1 0.0 2.4 2 1 1 3 3 3 0 UCH-binding domain EBP PF05241.12 KZN94335.1 - 2.7e-60 202.9 12.0 3.2e-60 202.6 12.0 1.0 1 0 0 1 1 1 1 Emopamil binding protein adh_short_C2 PF13561.6 KZN94336.1 - 3.6e-49 167.4 0.1 4.1e-49 167.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN94336.1 - 1e-34 119.7 0.0 2.1e-34 118.7 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN94336.1 - 0.00013 21.9 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1929 PF09118.11 KZN94338.1 - 1.3e-12 47.9 0.0 2.5e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) DUF2347 PF09804.9 KZN94339.1 - 9.8e-101 337.1 0.0 1.3e-100 336.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 KZN94339.1 - 2e-59 201.2 0.1 3e-59 200.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) Avl9 PF09794.9 KZN94339.1 - 0.001 17.9 0.0 1.2 7.8 0.0 2.4 2 1 0 2 2 2 2 Transport protein Avl9 SPA PF08616.10 KZN94339.1 - 0.047 13.7 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 Stabilization of polarity axis 2OG-FeII_Oxy_5 PF13759.6 KZN94340.1 - 0.17 12.3 0.9 0.92 10.0 0.1 2.6 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase DUF724 PF05266.14 KZN94340.1 - 0.33 10.8 12.1 0.3 10.9 10.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF724) AATF-Che1 PF13339.6 KZN94340.1 - 0.41 11.3 9.4 1.9 9.2 9.4 2.3 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor FapA PF03961.13 KZN94340.1 - 0.67 8.5 6.3 0.94 8.0 6.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc7 PF08317.11 KZN94340.1 - 2.6 6.9 19.0 5.3 5.8 19.0 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein CorA PF01544.18 KZN94340.1 - 3.9 6.7 7.0 7.8 5.7 7.0 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF641 PF04859.12 KZN94340.1 - 5.8 7.3 11.8 2.1 8.7 8.1 2.2 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) Tubulin_3 PF14881.6 KZN94341.1 - 5.3e-86 286.9 0.3 1.1e-85 285.8 0.3 1.6 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 KZN94341.1 - 4.5e-44 149.5 0.7 2.8e-43 147.0 0.1 2.6 3 0 0 3 3 3 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 KZN94341.1 - 0.0012 19.1 0.0 0.54 10.4 0.0 2.6 3 0 0 3 3 3 2 Tubulin/FtsZ family, GTPase domain DUF4072 PF13284.6 KZN94341.1 - 0.29 11.6 0.9 1 9.9 0.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4072) HSP70 PF00012.20 KZN94343.1 - 3.4e-66 223.7 3.2 3.4e-66 223.7 3.2 2.5 2 1 0 2 2 2 1 Hsp70 protein Keratin_2_head PF16208.5 KZN94344.1 - 5 7.3 36.3 6.1 7.0 36.3 1.1 1 0 0 1 1 1 0 Keratin type II head TruD PF01142.18 KZN94345.1 - 1.5e-67 228.3 2.6 3.7e-62 210.5 0.2 3.8 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) SKG6 PF08693.10 KZN94346.1 - 1.5e-06 27.5 6.6 8.8e-05 21.8 0.3 3.4 3 0 0 3 3 3 2 Transmembrane alpha-helix domain DUF4448 PF14610.6 KZN94346.1 - 9.6e-05 22.2 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 KZN94346.1 - 0.00042 20.2 0.1 0.00097 19.1 0.1 1.6 1 0 0 1 1 1 1 TMEM154 protein family Mid2 PF04478.12 KZN94346.1 - 0.0091 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF3188 PF11384.8 KZN94346.1 - 0.016 14.9 1.0 0.042 13.6 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) Gram_pos_anchor PF00746.21 KZN94346.1 - 0.095 12.7 1.0 0.22 11.5 1.0 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF4010 PF13194.6 KZN94346.1 - 0.12 12.1 1.1 4.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) CbtA PF09490.10 KZN94346.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) EVI2A PF05399.11 KZN94346.1 - 1.8 8.1 5.2 0.62 9.6 0.7 2.0 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) HSP20 PF00011.21 KZN94347.1 - 1.3e-18 67.0 0.1 1.7e-17 63.4 0.1 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KZN94347.1 - 1.9e-07 30.5 0.0 1.3e-06 27.9 0.0 2.1 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Glyco_hydro_43 PF04616.14 KZN94349.1 - 3e-40 138.3 5.2 3.5e-40 138.1 5.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Na_H_Exchanger PF00999.21 KZN94350.1 - 5.3e-40 137.4 24.3 8.7e-40 136.7 24.3 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Abhydrolase_6 PF12697.7 KZN94351.1 - 0.00029 21.5 0.1 0.00044 20.9 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KZN94351.1 - 0.00088 19.5 0.9 0.0013 18.9 0.1 1.7 2 0 0 2 2 2 1 Thioesterase domain UPF0227 PF05728.12 KZN94351.1 - 0.0013 18.7 0.1 0.0032 17.4 0.1 1.7 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.13 KZN94351.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 KZN94351.1 - 0.017 14.9 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 KZN94351.1 - 0.044 13.0 0.0 0.081 12.2 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KZN94351.1 - 0.089 12.7 0.0 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 Lipase (class 3) RBP_receptor PF14752.6 KZN94351.1 - 0.18 10.4 0.3 0.25 9.9 0.3 1.1 1 0 0 1 1 1 0 Retinol binding protein receptor NCKAP5 PF15246.6 KZN94351.1 - 3.6 7.1 16.7 3 7.4 15.5 1.4 1 1 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein AIM3 PF17096.5 KZN94352.1 - 0.0025 18.7 0.7 0.0025 18.7 0.7 5.4 3 3 1 4 4 4 1 Altered inheritance of mitochondria protein 3 MT0933_antitox PF14013.6 KZN94352.1 - 2.4 8.5 14.1 65 3.9 0.1 4.8 2 1 2 4 4 4 0 MT0933-like antitoxin protein ELO PF01151.18 KZN94353.1 - 9.9e-85 284.0 7.6 1.2e-84 283.8 7.6 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family PRP38_assoc PF12871.7 KZN94353.1 - 1.3 9.7 5.1 2.2 8.9 5.1 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Glyco_hydro_35 PF01301.19 KZN94354.1 - 5e-79 266.2 0.7 8.8e-79 265.4 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KZN94354.1 - 1.1e-61 206.4 8.0 9e-35 119.7 0.1 3.2 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KZN94354.1 - 3.8e-59 199.5 0.4 7.3e-59 198.6 0.4 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KZN94354.1 - 7e-29 99.2 0.5 6.2e-28 96.2 0.1 2.4 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 KZN94354.1 - 4e-06 26.5 0.5 7.5e-06 25.6 0.5 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Fungal_trans_2 PF11951.8 KZN94355.1 - 2e-13 49.9 0.5 1.1e-05 24.5 0.6 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain COesterase PF00135.28 KZN94356.1 - 1.5e-65 222.1 0.0 2.1e-65 221.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KZN94356.1 - 4e-05 23.6 2.1 0.19 11.5 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KZN94356.1 - 0.0043 16.5 0.0 0.009 15.5 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KZN94356.1 - 0.016 14.8 0.1 0.045 13.4 0.0 1.6 2 0 0 2 2 2 0 Putative esterase DUF3237 PF11578.8 KZN94358.1 - 6.4e-17 61.8 0.0 2.1e-07 30.9 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3237) MFS_1 PF07690.16 KZN94359.1 - 1.9e-30 106.0 28.8 2.6e-30 105.6 28.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN94359.1 - 2.7e-13 49.6 7.9 2.7e-13 49.6 7.9 2.3 2 1 1 3 3 3 1 Sugar (and other) transporter PTR2 PF00854.21 KZN94359.1 - 0.00084 18.3 3.2 0.0016 17.3 3.2 1.5 1 0 0 1 1 1 1 POT family Hexapep PF00132.24 KZN94361.1 - 2.3e-08 33.4 4.8 0.0022 17.7 0.9 3.8 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KZN94361.1 - 6.8e-05 23.3 0.0 0.00014 22.3 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 KZN94361.1 - 0.00045 19.3 0.5 0.00074 18.6 0.5 1.3 1 0 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 KZN94361.1 - 0.0031 15.7 0.6 0.0044 15.2 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 KZN94361.1 - 0.13 12.0 5.3 5.7 6.8 1.7 3.2 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Spt20 PF12090.8 KZN94363.1 - 4.3e-61 206.5 1.8 4.3e-61 206.5 1.8 5.7 4 1 0 4 4 4 1 Spt20 family zf-C2H2 PF00096.26 KZN94364.1 - 2.4e-07 30.8 16.0 0.00033 20.9 3.6 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KZN94364.1 - 0.00014 22.1 4.8 0.00014 22.1 4.8 3.7 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KZN94364.1 - 0.00025 21.6 8.9 0.0064 17.2 3.0 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KZN94364.1 - 0.0015 19.1 4.8 0.5 11.0 0.5 2.5 1 1 1 2 2 2 2 FOXP coiled-coil domain Sina PF03145.16 KZN94364.1 - 0.076 12.9 1.9 0.11 12.4 1.9 1.2 1 0 0 1 1 1 0 Seven in absentia protein family zf-C2H2_6 PF13912.6 KZN94364.1 - 2 8.5 11.8 2.9 8.0 0.6 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KZN94364.1 - 6.7 7.1 7.1 7.7 6.9 1.1 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding MFS_1 PF07690.16 KZN94365.1 - 1e-30 106.9 25.9 5.9e-18 64.9 6.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KZN94365.1 - 2.9e-06 25.9 1.0 6e-06 24.8 0.3 1.6 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Ribonuclease_T2 PF00445.18 KZN94366.1 - 3e-45 154.7 1.0 4.6e-45 154.1 1.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family GT-D PF08759.11 KZN94366.1 - 0.0057 16.4 0.2 0.011 15.5 0.2 1.4 1 1 0 1 1 1 1 Glycosyltransferase GT-D fold BCNT PF07572.12 KZN94367.1 - 4.9e-25 87.4 1.0 1.4e-24 85.9 1.0 1.9 1 0 0 1 1 1 1 Bucentaur or craniofacial development CDC45 PF02724.14 KZN94367.1 - 3.8 5.7 12.4 4.9 5.3 12.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Sensor PF13796.6 KZN94370.1 - 0.1 12.6 0.1 0.1 12.6 0.1 2.9 2 1 0 2 2 2 0 Putative sensor DUF202 PF02656.15 KZN94370.1 - 6.6 7.3 13.3 4.4e+02 1.4 10.9 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Amidohydro_1 PF01979.20 KZN94371.1 - 1.9e-06 27.4 0.0 3.4e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 KZN94371.1 - 0.00019 21.4 0.0 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Mis12 PF05859.12 KZN94372.1 - 7.3e-46 155.6 0.0 1.2e-45 154.8 0.0 1.4 1 0 0 1 1 1 1 Mis12 protein CENP-X PF09415.10 KZN94374.1 - 2.7e-28 98.1 0.2 6.9e-28 96.8 0.0 1.7 2 0 0 2 2 2 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.23 KZN94374.1 - 0.0046 17.2 0.0 0.0083 16.4 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Apt1 PF10351.9 KZN94374.1 - 0.15 10.9 7.7 0.17 10.7 7.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2934 PF11154.8 KZN94374.1 - 0.19 11.4 1.6 0.32 10.7 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2934) SMYLE_N PF18615.1 KZN94374.1 - 0.25 10.9 5.9 0.27 10.7 5.9 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain PIEZO PF15917.5 KZN94374.1 - 0.77 9.2 4.0 1 8.8 4.0 1.2 1 0 0 1 1 1 0 Piezo Hamartin PF04388.12 KZN94374.1 - 7.3 5.1 15.1 8.6 4.9 15.1 1.0 1 0 0 1 1 1 0 Hamartin protein SPX PF03105.19 KZN94374.1 - 8.8 6.1 17.5 11 5.8 17.5 1.1 1 0 0 1 1 1 0 SPX domain Macro PF01661.21 KZN94375.1 - 2.3e-10 40.5 0.0 6.3e-09 35.9 0.0 2.3 1 1 0 1 1 1 1 Macro domain MIF PF01187.18 KZN94376.1 - 3.6e-07 30.5 0.0 7e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) bZIP_1 PF00170.21 KZN94377.1 - 0.0057 16.7 0.4 0.011 15.8 0.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor Oxidored_FMN PF00724.20 KZN94378.1 - 4.7e-40 137.9 0.0 6.4e-40 137.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Epimerase PF01370.21 KZN94379.1 - 1.3e-16 60.8 0.0 3.7e-16 59.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KZN94379.1 - 4.5e-09 35.7 0.0 3.8e-08 32.7 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KZN94379.1 - 8e-08 32.4 0.3 1.4e-07 31.6 0.1 1.5 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KZN94379.1 - 3.3e-07 30.0 0.3 1.5e-05 24.5 0.0 2.8 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KZN94379.1 - 8e-06 25.2 0.0 0.0013 18.0 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KZN94379.1 - 7e-05 22.5 0.1 0.00014 21.5 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 KZN94379.1 - 0.001 18.6 0.2 0.0037 16.7 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KZN94379.1 - 0.0032 16.6 0.0 0.0061 15.7 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.26 KZN94380.1 - 1.5e-10 41.1 0.3 2.5e-10 40.4 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KZN94380.1 - 9.2e-07 28.7 0.1 5.4e-06 26.3 0.1 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KZN94380.1 - 0.022 15.8 0.1 0.062 14.4 0.1 1.9 1 1 0 1 1 1 0 Zinc-binding dehydrogenase adh_short PF00106.25 KZN94381.1 - 5e-37 127.3 0.1 7.2e-37 126.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN94381.1 - 3.7e-23 82.3 0.8 4.6e-23 82.0 0.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN94381.1 - 1.5e-05 25.0 0.1 2.8e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KZN94381.1 - 2e-05 24.2 0.0 0.021 14.2 0.0 2.1 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) NmrA PF05368.13 KZN94382.1 - 5.9e-29 101.3 0.0 2.1e-28 99.5 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KZN94382.1 - 9.3e-09 35.4 0.0 1.3e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 KZN94382.1 - 0.00015 22.0 0.0 0.00027 21.2 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.21 KZN94382.1 - 0.00049 19.6 0.0 0.00083 18.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KZN94382.1 - 0.033 13.2 0.0 0.045 12.7 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KZN94382.1 - 0.045 13.2 0.0 0.068 12.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Pkinase PF00069.25 KZN94383.1 - 0.00016 21.1 0.0 0.0002 20.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Phage_Coat_B PF05356.11 KZN94385.1 - 0.025 14.5 0.1 0.042 13.8 0.1 1.4 1 0 0 1 1 1 0 Phage Coat protein B A_deaminase PF00962.22 KZN94386.1 - 1.1e-22 80.8 0.0 9.2e-22 77.8 0.0 2.2 1 1 0 1 1 1 1 Adenosine/AMP deaminase His_Phos_2 PF00328.22 KZN94387.1 - 7.8e-37 127.5 0.0 9.7e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Aldedh PF00171.22 KZN94388.1 - 9.9e-184 611.1 0.4 1.1e-183 611.0 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FAD_binding_3 PF01494.19 KZN94389.1 - 3.2e-15 56.2 1.5 1.8e-11 43.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KZN94389.1 - 5.3e-08 33.0 0.4 1.6e-07 31.5 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KZN94389.1 - 8.2e-06 25.1 0.1 1.2e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KZN94389.1 - 1e-05 25.3 5.1 1.7e-05 24.6 4.4 1.6 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KZN94389.1 - 0.00027 20.3 3.8 0.00062 19.1 1.7 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KZN94389.1 - 0.00034 20.0 0.1 0.019 14.2 0.1 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KZN94389.1 - 0.0013 17.9 3.7 0.0023 17.1 3.4 1.6 1 1 1 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KZN94389.1 - 0.0028 17.1 0.1 0.0042 16.5 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KZN94389.1 - 0.0055 17.2 1.6 0.015 15.8 1.6 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KZN94389.1 - 0.019 14.1 1.7 0.019 14.1 1.7 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A Rossmann-like PF10727.9 KZN94389.1 - 0.021 14.7 0.6 0.048 13.5 0.6 1.6 1 0 0 1 1 1 0 Rossmann-like domain 3HCDH_N PF02737.18 KZN94389.1 - 0.1 12.4 2.0 0.21 11.5 2.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 KZN94389.1 - 0.12 11.0 1.9 0.18 10.5 1.9 1.2 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 KZN94389.1 - 0.3 9.9 4.0 1.8 7.3 1.8 2.6 3 0 0 3 3 3 0 Tryptophan halogenase Fungal_trans PF04082.18 KZN94393.1 - 1.1e-11 44.3 0.0 2.2e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN94393.1 - 1.9e-05 24.7 8.7 3.8e-05 23.7 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Smg4_UPF3 PF03467.15 KZN94394.1 - 2.8e-43 148.0 0.0 2.8e-43 148.0 0.0 2.7 2 1 0 2 2 2 1 Smg-4/UPF3 family RRM_1 PF00076.22 KZN94394.1 - 1.3e-08 34.5 0.0 7.3e-07 28.9 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M19 PF01244.21 KZN94395.1 - 1.1e-100 336.9 0.0 1.3e-100 336.7 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Peptidase_M35 PF02102.15 KZN94396.1 - 3.1e-180 598.7 11.9 3.4e-180 598.6 11.9 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KZN94396.1 - 7.4e-40 136.8 5.0 7.4e-40 136.8 5.0 1.5 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase CARDB PF07705.11 KZN94396.1 - 0.0079 16.4 0.3 0.34 11.2 0.0 2.4 2 0 0 2 2 2 1 CARDB HMGL-like PF00682.19 KZN94396.1 - 0.026 14.1 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 HMGL-like Pox_RNA_Pol_22 PF05273.13 KZN94396.1 - 0.081 12.7 0.0 0.47 10.2 0.0 2.0 2 0 0 2 2 2 0 Poxvirus RNA polymerase 22 kDa subunit Sua5_yciO_yrdC PF01300.18 KZN94398.1 - 2.4e-10 40.2 0.0 6.4e-10 38.8 0.0 1.7 1 1 0 1 1 1 1 Telomere recombination HalOD1 PF18545.1 KZN94398.1 - 0.0012 19.1 0.0 0.0026 18.0 0.0 1.6 1 0 0 1 1 1 1 Halobacterial output domain 1 Peptidase_A4 PF01828.17 KZN94399.1 - 1.9e-73 246.4 1.8 2.3e-73 246.1 1.8 1.1 1 0 0 1 1 1 1 Peptidase A4 family PHY PF00360.20 KZN94400.1 - 4.1e-30 104.5 0.0 7.7e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 KZN94400.1 - 7.5e-17 61.9 0.1 1.7e-16 60.7 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KZN94400.1 - 4.2e-15 55.9 0.0 8.4e-14 51.7 0.0 3.0 3 1 0 3 3 3 1 Response regulator receiver domain GAF PF01590.26 KZN94400.1 - 1e-11 45.6 0.2 7.5e-11 42.8 0.0 2.6 3 0 0 3 3 3 1 GAF domain PAS_2 PF08446.11 KZN94400.1 - 2.5e-10 41.0 0.0 1.7e-08 35.1 0.0 2.8 2 0 0 2 2 2 1 PAS fold HisKA PF00512.25 KZN94400.1 - 3.9e-10 39.6 1.0 1.3e-09 37.9 1.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain F-box PF00646.33 KZN94402.1 - 0.11 12.4 1.4 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 F-box domain Bac_rhamnosid6H PF17389.2 KZN94405.1 - 7.2e-132 439.7 0.1 9.4e-132 439.4 0.1 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KZN94405.1 - 2.2e-56 190.4 0.0 5.8e-56 189.0 0.0 1.8 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 KZN94405.1 - 5.4e-28 97.0 0.0 9.9e-28 96.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 KZN94405.1 - 4.2e-21 74.5 0.3 1.1e-20 73.1 0.0 1.8 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 KZN94406.1 - 3.3e-88 296.2 0.1 4.8e-88 295.7 0.1 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KZN94406.1 - 2.8e-52 177.0 0.0 4.5e-52 176.3 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 KZN94406.1 - 9.6e-18 64.1 0.0 2.4e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 KZN94406.1 - 1e-15 57.3 0.0 2.1e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain DUF608 PF04685.13 KZN94406.1 - 0.018 14.2 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region CBM60 PF16841.5 KZN94406.1 - 0.089 13.2 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Ca-dependent carbohydrate-binding module xylan-binding Metallophos PF00149.28 KZN94407.1 - 2.4e-11 44.5 1.7 3.9e-11 43.8 1.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KZN94407.1 - 2.3e-07 31.2 0.4 4.1e-06 27.1 0.4 2.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Sugar_tr PF00083.24 KZN94408.1 - 4.2e-101 339.0 25.9 4.9e-101 338.8 25.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN94408.1 - 1.9e-28 99.4 40.5 8e-26 90.8 22.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LapA_dom PF06305.11 KZN94408.1 - 1.5 8.7 4.8 0.8 9.6 1.3 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Fungal_trans PF04082.18 KZN94409.1 - 7.6e-07 28.4 0.2 1.2e-06 27.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ComX PF05952.12 KZN94409.1 - 0.0054 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Bacillus competence pheromone ComX PIF1 PF05970.14 KZN94413.1 - 6.3e-22 78.2 0.0 9.4e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KZN94413.1 - 1.8e-11 44.1 0.0 3.6e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KZN94413.1 - 9.1e-06 26.1 0.1 3.2e-05 24.3 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KZN94413.1 - 0.002 18.0 0.7 0.81 9.4 0.0 2.7 2 1 1 3 3 3 2 AAA domain KAP_NTPase PF07693.14 KZN94413.1 - 0.091 12.0 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain ABC_tran_CTD PF16326.5 KZN94413.1 - 0.41 10.9 2.9 4.6 7.6 1.7 2.5 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF4224 PF13986.6 KZN94415.1 - 0.037 13.9 0.1 0.065 13.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) AphA_like PF14557.6 KZN94416.1 - 0.024 14.4 1.5 0.026 14.2 0.7 1.4 2 0 0 2 2 2 0 Putative AphA-like transcriptional regulator RPW8 PF05659.11 KZN94416.1 - 0.1 12.3 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 RHH_1 PF01402.21 KZN94417.1 - 0.055 13.4 2.8 0.6 10.1 0.2 2.5 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Plk4_PB1 PF18190.1 KZN94417.1 - 0.1 12.8 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 Polo-like Kinase 4 Polo Box 1 SlyX PF04102.12 KZN94417.1 - 2.6 8.8 7.1 2 9.1 5.3 1.7 1 1 1 2 2 2 0 SlyX SUR7 PF06687.12 KZN94418.1 - 5.7e-25 88.2 12.5 7.9e-25 87.7 12.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family SCIMP PF15050.6 KZN94418.1 - 0.2 12.1 0.0 0.47 10.9 0.0 1.6 1 0 0 1 1 1 0 SCIMP protein DUF3433 PF11915.8 KZN94419.1 - 7.9e-37 125.6 26.8 2.5e-28 98.4 3.5 3.8 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) DUF2076 PF09849.9 KZN94420.1 - 0.17 11.9 3.0 2.5 8.1 0.7 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) G-patch PF01585.23 KZN94421.1 - 3e-13 49.4 0.4 5.5e-13 48.6 0.4 1.5 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 KZN94421.1 - 1.8e-09 37.2 0.0 0.00023 20.9 0.0 3.4 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 KZN94421.1 - 1.1e-07 31.0 1.7 2.3e-07 30.0 1.7 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.7 KZN94421.1 - 6.2e-07 29.4 0.4 1.6e-06 28.1 0.4 1.7 1 0 0 1 1 1 1 G-patch domain RED_N PF07808.13 KZN94421.1 - 0.77 9.3 7.0 0.057 13.0 0.6 2.3 2 0 0 2 2 2 0 RED-like protein N-terminal region FAP PF07174.11 KZN94421.1 - 1.3 8.5 32.0 0.23 10.9 14.7 2.4 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) Alpha-amylase PF00128.24 KZN94422.1 - 2.4e-112 375.8 3.3 3.9e-112 375.2 3.3 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KZN94422.1 - 1.2e-06 28.6 0.0 2.2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KZN94422.1 - 0.0083 15.3 0.1 0.013 14.6 0.1 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain MoaE PF02391.17 KZN94423.1 - 1e-34 119.2 0.0 1.3e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 MoaE protein SCO1-SenC PF02630.14 KZN94424.1 - 3.5e-47 159.7 0.4 5.6e-47 159.0 0.1 1.5 2 0 0 2 2 2 1 SCO1/SenC AhpC-TSA PF00578.21 KZN94424.1 - 8.8e-05 22.4 0.5 0.00048 20.0 0.0 2.2 2 1 0 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KZN94424.1 - 0.0014 18.9 0.0 0.0034 17.7 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Pox_A12 PF04651.13 KZN94424.1 - 0.076 13.1 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A12 protein Redoxin PF08534.10 KZN94424.1 - 0.079 12.7 0.3 0.26 11.0 0.0 2.0 2 1 0 2 2 2 0 Redoxin Phosphoesterase PF04185.14 KZN94425.1 - 2e-58 198.3 0.8 3.6e-58 197.5 0.8 1.4 1 1 0 1 1 1 1 Phosphoesterase family FAD_binding_3 PF01494.19 KZN94426.1 - 4.4e-82 276.1 0.1 5.6e-82 275.8 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KZN94426.1 - 4.5e-05 22.8 0.1 0.0016 17.7 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN94426.1 - 5.6e-05 23.3 0.1 0.0002 21.5 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KZN94426.1 - 0.00016 21.3 0.8 0.00096 18.8 0.2 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KZN94426.1 - 0.00065 18.5 0.0 0.0018 17.0 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KZN94426.1 - 0.00071 18.8 0.1 0.0016 17.6 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KZN94426.1 - 0.00092 19.7 0.1 0.059 13.9 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KZN94426.1 - 0.0023 17.0 0.0 0.008 15.3 0.0 1.8 1 1 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.12 KZN94426.1 - 0.0045 16.1 0.2 0.055 12.5 0.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KZN94426.1 - 0.012 14.9 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family XdhC_C PF13478.6 KZN94426.1 - 0.034 14.7 0.0 0.79 10.2 0.0 2.8 3 0 0 3 3 3 0 XdhC Rossmann domain NAD_binding_9 PF13454.6 KZN94426.1 - 0.085 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding ApbA PF02558.16 KZN94426.1 - 0.12 12.0 0.1 0.26 10.9 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 KZN94426.1 - 0.14 11.3 0.1 0.25 10.6 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.18 KZN94427.1 - 1.5e-16 60.3 0.2 2.1e-16 59.7 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF5393 PF17371.2 KZN94427.1 - 0.0074 14.5 0.3 0.01 14.0 0.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5393) Fungal_trans PF04082.18 KZN94429.1 - 2.9e-07 29.8 0.5 6.1e-07 28.7 0.5 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain SNARE PF05739.19 KZN94430.1 - 8.1e-13 48.2 0.1 2.2e-12 46.7 0.1 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 KZN94430.1 - 3.5e-07 29.2 0.0 1.1e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain KxDL PF10241.9 KZN94430.1 - 7.9e-05 22.9 0.3 0.25 11.6 0.1 2.9 2 0 0 2 2 2 2 Uncharacterized conserved protein Syntaxin PF00804.25 KZN94430.1 - 0.0062 16.2 6.9 0.024 14.3 0.1 2.9 2 1 1 3 3 3 1 Syntaxin DUF4988 PF16378.5 KZN94430.1 - 0.028 14.1 3.4 11 5.7 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function SPATA48 PF15073.6 KZN94430.1 - 0.034 14.4 0.2 0.083 13.2 0.2 1.7 1 0 0 1 1 1 0 Spermatogenesis-associated protein 48 DUF948 PF06103.11 KZN94430.1 - 0.18 12.0 0.8 4.2 7.7 0.0 3.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 KZN94430.1 - 0.34 11.4 2.3 1e+02 3.5 0.1 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF16 PF01519.16 KZN94430.1 - 1.2 9.7 4.4 0.79 10.2 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function DUF16 SlyX PF04102.12 KZN94430.1 - 9.5 6.9 7.9 0.97 10.1 0.2 2.8 3 0 0 3 3 3 0 SlyX DIOX_N PF14226.6 KZN94432.1 - 5.4e-32 111.0 0.1 8.5e-32 110.4 0.1 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KZN94432.1 - 2.4e-23 82.5 0.0 4.2e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily E1-E2_ATPase PF00122.20 KZN94433.1 - 1.9e-36 125.3 8.6 3.5e-36 124.4 0.4 3.8 3 2 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KZN94433.1 - 1.9e-17 64.3 0.0 5.2e-17 62.8 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KZN94433.1 - 3e-10 39.6 0.2 1.3e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KZN94433.1 - 0.0052 16.6 0.1 0.0099 15.6 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KZN94433.1 - 0.019 15.0 0.0 0.045 13.8 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Lactamase_B PF00753.27 KZN94434.1 - 2.9e-07 30.7 1.4 2.6e-05 24.3 1.4 2.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KZN94434.1 - 0.00043 19.9 1.1 0.0012 18.4 0.2 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain ABC1 PF03109.16 KZN94436.1 - 3.2e-20 72.5 0.4 1.4e-19 70.4 0.1 2.1 2 0 0 2 2 2 1 ABC1 family APH PF01636.23 KZN94436.1 - 0.026 14.4 0.0 0.079 12.9 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family SnoaL_2 PF12680.7 KZN94437.1 - 0.062 14.0 0.0 0.14 12.8 0.0 1.8 1 1 0 1 1 1 0 SnoaL-like domain TFIIS_M PF07500.14 KZN94438.1 - 2.6e-28 98.8 0.1 5.3e-28 97.7 0.1 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KZN94438.1 - 9.5e-18 63.8 4.8 1.8e-17 62.9 4.8 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KZN94438.1 - 4.5e-10 39.4 0.3 4.5e-10 39.4 0.3 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.8 KZN94438.1 - 0.015 15.0 0.9 0.045 13.4 0.0 2.1 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain MFS_1 PF07690.16 KZN94439.1 - 6.2e-35 120.8 37.6 3.2e-34 118.4 37.6 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Pox_A14 PF05767.12 KZN94439.1 - 0.34 11.1 3.8 2 8.6 0.4 3.4 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 DUF5392 PF17370.2 KZN94439.1 - 3.1 7.9 5.0 3.5 7.7 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5392) Myb_DNA-binding PF00249.31 KZN94440.1 - 6.9e-05 23.0 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KZN94440.1 - 0.0002 21.5 0.0 0.00041 20.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain AIF-MLS PF14962.6 KZN94440.1 - 0.11 12.5 1.8 0.17 11.8 0.2 2.0 1 1 1 2 2 2 0 Mitochondria Localisation Sequence Pkinase PF00069.25 KZN94441.1 - 1.2e-09 38.0 0.0 2.3e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KZN94441.1 - 1.6e-06 27.6 0.0 5.7e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KZN94441.1 - 0.0017 18.3 0.0 0.0027 17.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KZN94441.1 - 0.0051 16.2 0.0 0.009 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KZN94441.1 - 0.061 12.6 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 KZN94441.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase AAA PF00004.29 KZN94442.1 - 2.5e-19 70.0 0.1 1.3e-17 64.5 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KZN94442.1 - 0.0065 16.7 1.7 6.3 7.1 0.0 3.3 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 KZN94442.1 - 0.0097 16.3 0.8 0.078 13.3 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.6 KZN94442.1 - 0.021 15.2 0.0 0.089 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KZN94442.1 - 0.029 14.9 0.0 0.088 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KZN94442.1 - 0.078 13.0 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KZN94442.1 - 0.094 12.8 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 KZN94442.1 - 0.14 11.9 0.0 5.8 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain DASH_Dad1 PF08649.10 KZN94442.1 - 4.5 7.6 5.0 7 6.9 0.1 3.5 4 0 0 4 4 4 0 DASH complex subunit Dad1 Kdo PF06293.14 KZN94443.1 - 7.2e-05 22.2 0.0 0.00019 20.9 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KZN94443.1 - 0.016 15.1 10.0 0.017 15.1 0.1 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase PF00069.25 KZN94443.1 - 0.025 14.0 0.0 0.058 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein kinase domain DUF3584 PF12128.8 KZN94443.1 - 0.037 11.6 16.0 0.055 11.0 16.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2828 PF11443.8 KZN94443.1 - 0.052 11.6 4.3 0.079 11.0 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Presenilin PF01080.17 KZN94443.1 - 0.18 10.5 7.3 0.039 12.7 0.8 2.1 2 0 0 2 2 2 0 Presenilin RIO1 PF01163.22 KZN94443.1 - 0.33 10.5 0.0 0.33 10.5 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Afi1 PF07792.12 KZN94443.1 - 3.6 8.1 9.2 9.3 6.7 9.2 1.6 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking gag_pre-integrs PF13976.6 KZN94445.1 - 4e-06 26.6 0.0 7.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.26 KZN94445.1 - 0.00051 20.2 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain HTH_18 PF12833.7 KZN94445.1 - 0.036 14.3 0.1 0.29 11.4 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain AbiEii PF08843.11 KZN94446.1 - 0.02 14.9 0.0 0.029 14.3 0.0 1.6 1 1 0 1 1 1 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system Metallophos PF00149.28 KZN94447.1 - 3.7e-10 40.6 0.4 5.7e-10 40.0 0.4 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase E1-E2_ATPase PF00122.20 KZN94448.1 - 8.2e-48 162.3 3.2 1.8e-47 161.2 3.2 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KZN94448.1 - 1.1e-21 78.1 0.0 1.9e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KZN94448.1 - 1.5e-06 28.5 0.1 4.9e-06 26.9 0.1 1.9 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KZN94448.1 - 0.00095 19.0 0.0 0.0028 17.4 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribosomal_L7Ae PF01248.26 KZN94448.1 - 0.0071 16.1 0.0 0.021 14.5 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family MauE PF07291.11 KZN94448.1 - 1.5 8.5 7.6 0.43 10.3 1.8 2.5 2 0 0 2 2 2 0 Methylamine utilisation protein MauE SCAMP PF04144.13 KZN94448.1 - 3.2 8.0 7.5 1.1 9.6 3.5 2.1 2 0 0 2 2 2 0 SCAMP family PilJ PF13675.6 KZN94449.1 - 0.013 15.5 0.2 0.037 14.1 0.2 1.7 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Cu-oxidase_2 PF07731.14 KZN94450.1 - 6.8e-43 145.7 9.0 2.6e-36 124.4 4.0 4.3 3 2 1 4 4 4 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KZN94450.1 - 2.8e-42 143.5 2.6 3.3e-40 136.8 0.0 4.1 5 0 0 5 5 5 1 Multicopper oxidase Cu-oxidase PF00394.22 KZN94450.1 - 4.4e-20 72.4 1.9 2.6e-13 50.4 0.0 3.3 2 1 0 3 3 3 2 Multicopper oxidase E1-E2_ATPase PF00122.20 KZN94451.1 - 3.4e-47 160.3 0.3 8.9e-47 158.9 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KZN94451.1 - 9.8e-33 114.2 0.4 1.9e-32 113.3 0.4 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KZN94451.1 - 4.2e-30 104.0 0.7 6.4e-13 48.9 0.0 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KZN94451.1 - 9.3e-06 25.6 0.1 3.8e-05 23.5 0.1 1.9 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase SNAD4 PF18750.1 KZN94451.1 - 0.0091 16.1 1.6 0.38 10.9 0.0 3.5 3 1 1 4 4 4 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 KZN94451.1 - 0.15 12.1 1.2 1.1 9.3 0.0 2.9 4 0 0 4 4 4 0 Novel AID APOBEC clade 1 BIR PF00653.21 KZN94452.1 - 0.0019 18.8 1.6 0.0033 18.0 1.6 1.5 1 1 0 1 1 1 1 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 KZN94452.1 - 0.15 12.1 3.1 5.1 7.1 3.1 2.1 1 1 0 1 1 1 0 C3HC zinc finger-like NCD3G PF07562.14 KZN94452.1 - 1.2 9.2 6.7 15 5.6 3.2 2.2 1 1 1 2 2 2 0 Nine Cysteines Domain of family 3 GPCR DUF3435 PF11917.8 KZN94453.1 - 8.5e-07 28.2 0.0 1.3e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Herpes_LAMP2 PF06126.11 KZN94454.1 - 0.1 11.2 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Cu-oxidase_2 PF07731.14 KZN94455.1 - 1.3e-42 144.8 6.1 8.8e-36 122.7 0.6 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KZN94455.1 - 1.3e-40 138.1 6.1 8.8e-40 135.4 0.1 3.6 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 KZN94455.1 - 5e-21 75.5 0.3 2.3e-15 57.0 0.0 2.9 3 0 0 3 3 3 2 Multicopper oxidase Zip PF02535.22 KZN94456.1 - 1.3e-57 195.5 6.5 2.1e-57 194.8 6.5 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter DUF3435 PF11917.8 KZN94458.1 - 8.1e-139 463.1 3.3 1.3e-138 462.5 3.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Aa_trans PF01490.18 KZN94459.1 - 1.4e-46 159.1 35.6 1.6e-46 158.8 35.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MFS_1 PF07690.16 KZN94460.1 - 6.5e-16 58.2 6.4 6.5e-16 58.2 6.4 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN94460.1 - 0.0028 16.6 0.8 0.0028 16.6 0.8 1.4 2 0 0 2 2 2 1 Sugar (and other) transporter Glyco_hydro_71 PF03659.14 KZN94461.1 - 3.2e-129 431.0 12.4 4.6e-129 430.5 12.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Lipase_GDSL_2 PF13472.6 KZN94461.1 - 5.4e-10 39.9 0.7 1.8e-09 38.2 0.7 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Aspzincin_M35 PF14521.6 KZN94461.1 - 3.6e-07 30.8 0.2 2.3e-06 28.2 0.0 2.5 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase Lipase_GDSL PF00657.22 KZN94461.1 - 0.0097 15.9 0.1 0.023 14.6 0.1 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase LRR_6 PF13516.6 KZN94463.1 - 2.2e-12 45.9 2.6 0.12 12.5 0.1 7.1 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.7 KZN94463.1 - 6e-06 26.5 6.3 0.39 11.2 0.1 4.9 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KZN94463.1 - 0.0018 18.0 4.9 0.13 12.0 0.2 4.3 3 2 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.33 KZN94463.1 - 0.013 16.0 4.6 47 5.1 0.0 5.4 6 0 0 6 6 5 0 Leucine Rich Repeat SipA_VBS PF17985.1 KZN94463.1 - 0.055 13.4 0.5 20 5.3 0.2 2.9 2 0 0 2 2 2 0 SipA vinculin binding site SDA1 PF05285.12 KZN94463.1 - 1.7 8.0 18.0 2.4 7.5 18.0 1.3 1 0 0 1 1 1 0 SDA1 DARPP-32 PF05395.12 KZN94463.1 - 2.6 8.3 12.0 4.4 7.5 12.0 1.4 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 NOA36 PF06524.12 KZN94463.1 - 4.7 6.4 10.7 6.6 6.0 10.7 1.3 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 KZN94463.1 - 5.9 5.0 18.6 7.7 4.6 18.6 1.1 1 0 0 1 1 1 0 Nop14-like family Auts2 PF15336.6 KZN94463.1 - 6 6.9 4.8 10 6.2 4.8 1.4 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein PTPRCAP PF15713.5 KZN94463.1 - 8 6.7 18.6 18 5.6 18.6 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated COX17 PF05051.13 KZN94464.1 - 1.6e-21 76.3 7.0 2e-21 76.0 7.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 KZN94464.1 - 0.014 15.4 2.8 0.24 11.4 0.1 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.12 KZN94464.1 - 0.93 9.8 7.0 1.6 9.0 7.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Alg6_Alg8 PF03155.15 KZN94465.1 - 1.1e-129 433.6 20.3 2e-128 429.4 20.3 2.0 1 1 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family RRM_1 PF00076.22 KZN94466.1 - 3.8e-44 148.4 0.0 1.1e-20 73.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KZN94466.1 - 2.9e-06 27.3 0.0 0.13 12.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif Herpes_pp38 PF04846.13 KZN94467.1 - 0.2 11.6 0.1 0.37 10.7 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein FMN_bind_2 PF04299.12 KZN94468.1 - 7.8e-57 191.6 0.1 9.3e-57 191.4 0.1 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Ring_hydroxyl_A PF00848.19 KZN94469.1 - 1.5e-19 70.9 2.1 9.6e-17 61.7 2.1 2.2 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KZN94469.1 - 8.9e-15 54.4 0.0 1.8e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain CDI PF02234.19 KZN94469.1 - 0.54 10.5 4.1 5.6 7.2 4.1 2.7 2 1 0 2 2 2 0 Cyclin-dependent kinase inhibitor Dioxygenase_C PF00775.21 KZN94470.1 - 3.3e-40 137.5 0.0 4.3e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KZN94470.1 - 2.8e-24 84.8 0.0 4.6e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CSS-motif PF12792.7 KZN94470.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 CSS motif domain associated with EAL NAD_binding_10 PF13460.6 KZN94472.1 - 0.0041 17.0 0.0 0.018 15.0 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KZN94472.1 - 0.1 11.6 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MoeA_N PF03453.17 KZN94473.1 - 1.2e-32 112.8 0.5 1.9e-32 112.2 0.5 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 KZN94473.1 - 4.2e-31 107.5 0.0 1.5e-15 57.1 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_C PF03454.15 KZN94473.1 - 1.7e-10 40.9 0.1 4.7e-10 39.5 0.1 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) MFS_1 PF07690.16 KZN94475.1 - 1.1e-32 113.4 31.2 1.1e-32 113.4 31.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily adh_short_C2 PF13561.6 KZN94476.1 - 3.8e-51 173.9 0.0 4.8e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KZN94476.1 - 1.8e-45 154.8 0.2 2.2e-45 154.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KZN94476.1 - 3.3e-08 33.6 0.0 5.3e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KZN94476.1 - 0.0075 15.8 0.2 0.017 14.6 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KZN94476.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Fungal_trans_2 PF11951.8 KZN94477.1 - 1.9e-13 50.0 0.0 4.9e-13 48.6 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN94477.1 - 1.7e-07 31.2 10.3 1.7e-07 31.2 10.3 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YihI PF04220.12 KZN94477.1 - 0.026 14.3 0.4 0.051 13.3 0.0 1.7 2 0 0 2 2 2 0 Der GTPase activator (YihI) Transketolase_N PF00456.21 KZN94478.1 - 2.7e-122 407.9 0.1 6.3e-122 406.7 0.0 1.6 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KZN94478.1 - 2.4e-38 131.6 0.2 5.5e-38 130.4 0.2 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.6 KZN94478.1 - 2.3e-06 27.0 0.0 9.9e-06 25.0 0.0 1.9 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 KZN94478.1 - 4.7e-06 25.8 0.1 1.1e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KZN94478.1 - 8.4e-05 22.4 2.5 0.0022 17.8 1.1 2.9 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_C PF02780.20 KZN94478.1 - 0.0016 18.3 0.0 0.0048 16.8 0.0 1.8 1 1 0 1 1 1 1 Transketolase, C-terminal domain GSHPx PF00255.19 KZN94478.1 - 0.044 13.4 0.0 13 5.4 0.0 2.5 2 0 0 2 2 2 0 Glutathione peroxidase Fungal_trans PF04082.18 KZN94479.1 - 7.8e-13 48.1 3.8 1.4e-12 47.2 3.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN94479.1 - 8.8e-09 35.4 10.8 1.5e-08 34.6 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.12 KZN94480.1 - 1.2e-08 34.8 0.1 3.6e-08 33.2 0.1 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KZN94480.1 - 3.7e-05 23.7 0.1 8e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase LysM PF01476.20 KZN94482.1 - 2.5e-08 33.9 0.0 8.4e-05 22.6 0.2 2.6 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 KZN94482.1 - 0.00018 21.9 9.0 0.00018 21.9 9.0 2.8 2 1 0 2 2 2 1 Chitin recognition protein ESSS PF10183.9 KZN94482.1 - 0.091 13.0 0.8 0.52 10.5 0.3 2.2 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Glyco_hydro_72 PF03198.14 KZN94485.1 - 1.3e-134 448.5 3.1 1.6e-134 448.2 3.1 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KZN94485.1 - 7e-06 25.7 0.4 0.00019 21.0 0.4 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FA_hydroxylase PF04116.13 KZN94486.1 - 6.8e-22 78.2 13.7 6.8e-22 78.2 13.7 1.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily CoxIIa PF08113.11 KZN94486.1 - 2.3 8.1 5.4 4.5 7.2 0.5 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IIa family Tyrosinase PF00264.20 KZN94488.1 - 2.9e-51 174.9 0.1 3.6e-51 174.6 0.1 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase PARM PF17061.5 KZN94489.1 - 0.53 10.4 60.2 0.66 10.1 60.2 1.2 1 0 0 1 1 1 0 PARM SOBP PF15279.6 KZN94489.1 - 5 7.7 23.8 7.8 7.0 23.8 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein UQ_con PF00179.26 KZN94490.1 - 7.2e-37 126.2 0.0 8e-37 126.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KZN94490.1 - 0.0078 16.5 0.0 0.0089 16.3 0.0 1.3 1 0 0 1 1 1 1 RWD domain HhH-GPD PF00730.25 KZN94491.1 - 1.6e-20 73.6 0.0 5.3e-20 71.9 0.0 1.8 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KZN94491.1 - 3.1e-08 33.1 0.1 1.3e-07 31.1 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif YmgD PF16456.5 KZN94491.1 - 0.08 13.0 0.5 0.6 10.2 0.1 2.5 3 0 0 3 3 3 0 YmgD protein WRNPLPNID PF15017.6 KZN94491.1 - 0.087 13.7 0.5 2.7 8.9 0.3 2.6 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Haem_oxygenas_2 PF14518.6 KZN94491.1 - 0.11 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Iron-containing redox enzyme AAA_11 PF13086.6 KZN94492.1 - 9.1e-65 219.0 0.1 2.9e-64 217.4 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KZN94492.1 - 1.7e-55 187.8 0.0 2.7e-55 187.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KZN94492.1 - 4.6e-13 49.3 0.0 7.6e-12 45.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KZN94492.1 - 1.6e-09 38.3 0.0 4.3e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KZN94492.1 - 1.5e-07 31.4 0.0 0.14 11.9 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KZN94492.1 - 1.6e-06 27.6 0.3 2.4e-05 23.7 0.3 2.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KZN94492.1 - 2.3e-06 27.7 0.0 1.3e-05 25.3 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KZN94492.1 - 3.8e-06 27.2 0.1 0.0001 22.6 0.1 2.5 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KZN94492.1 - 7.1e-05 22.5 0.0 0.00018 21.1 0.0 1.7 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 KZN94492.1 - 0.00011 21.7 0.0 0.028 13.9 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein DEAD PF00270.29 KZN94492.1 - 0.00015 21.6 0.2 0.0033 17.2 0.2 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_RecD PF05127.14 KZN94492.1 - 0.00021 21.2 0.0 0.04 13.8 0.0 2.4 2 0 0 2 2 2 1 Helicase Flavi_DEAD PF07652.14 KZN94492.1 - 0.00057 19.9 0.1 0.0026 17.8 0.1 2.0 2 0 0 2 2 2 1 Flavivirus DEAD domain PIF1 PF05970.14 KZN94492.1 - 0.0008 18.7 0.0 0.61 9.2 0.0 2.4 2 0 0 2 2 2 2 PIF1-like helicase T2SSE PF00437.20 KZN94492.1 - 0.0016 17.6 0.0 0.0027 16.8 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_24 PF13479.6 KZN94492.1 - 0.0042 16.8 0.0 0.0097 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KZN94492.1 - 0.0058 17.0 0.0 0.011 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.6 KZN94492.1 - 0.0066 16.3 0.0 0.17 11.7 0.0 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_5 PF07728.14 KZN94492.1 - 0.0075 16.3 0.0 0.047 13.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) UvrD_C PF13361.6 KZN94492.1 - 0.02 14.3 0.0 4.9 6.4 0.0 2.7 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain AAA PF00004.29 KZN94492.1 - 0.031 14.7 0.0 0.17 12.3 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 KZN94492.1 - 0.044 12.7 0.0 0.072 12.0 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain IstB_IS21 PF01695.17 KZN94492.1 - 0.046 13.4 0.0 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein HEM4 PF02602.15 KZN94492.1 - 0.047 13.0 0.1 0.42 9.9 0.0 2.2 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD SKI PF01202.22 KZN94492.1 - 0.091 12.9 0.2 0.98 9.5 0.1 2.3 1 1 1 2 2 2 0 Shikimate kinase Mg_chelatase PF01078.21 KZN94492.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI FAD_binding_3 PF01494.19 KZN94493.1 - 2.2e-12 46.9 1.4 1e-11 44.7 1.4 1.8 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 KZN94493.1 - 0.014 14.4 0.0 0.092 11.8 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase Amino_oxidase PF01593.24 KZN94493.1 - 0.018 14.4 0.1 0.05 12.9 0.0 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KZN94493.1 - 0.033 13.4 0.6 1.5 7.9 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KZN94493.1 - 0.069 13.4 0.2 0.22 11.8 0.2 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Jas PF16135.5 KZN94493.1 - 0.13 12.4 0.0 0.63 10.3 0.0 2.0 2 0 0 2 2 2 0 TPL-binding domain in jasmonate signalling adh_short PF00106.25 KZN94494.1 - 2.8e-28 98.7 0.0 3.9e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN94494.1 - 1.8e-24 86.6 0.0 2.8e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KZN94494.1 - 0.00023 20.7 0.0 0.00035 20.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KZN94494.1 - 0.0018 18.2 0.1 0.011 15.6 0.1 2.0 1 1 0 1 1 1 1 KR domain Exo_endo_phos PF03372.23 KZN94494.1 - 0.018 14.5 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Sacchrp_dh_NADP PF03435.18 KZN94494.1 - 0.086 13.1 0.0 0.24 11.6 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DUF3712 PF12505.8 KZN94495.1 - 2.4e-34 118.3 0.1 4.2e-34 117.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) LEA_2 PF03168.13 KZN94495.1 - 0.071 13.6 0.1 0.77 10.3 0.1 2.5 2 1 0 2 2 2 0 Late embryogenesis abundant protein Sel1 PF08238.12 KZN94496.1 - 9.8e-12 45.2 6.4 0.0011 19.6 0.0 3.8 4 0 0 4 4 4 3 Sel1 repeat His_Phos_1 PF00300.22 KZN94496.1 - 0.049 13.3 0.3 0.087 12.5 0.3 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) LRR_4 PF12799.7 KZN94497.1 - 0.4 11.2 5.0 17 6.0 0.1 4.9 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) TRIQK PF15168.6 KZN94498.1 - 0.72 9.8 0.1 0.72 9.8 0.1 2.5 3 0 0 3 3 3 0 Triple QxxK/R motif-containing protein family DUF1776 PF08643.10 KZN94499.1 - 1.4e-104 349.6 0.0 1.7e-104 349.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.25 KZN94499.1 - 2.1e-05 24.1 0.0 0.00011 21.7 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN94499.1 - 0.014 15.0 0.0 1 8.9 0.0 2.3 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase WLM PF08325.10 KZN94500.1 - 9.6e-64 215.0 0.4 1.3e-63 214.5 0.4 1.2 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 KZN94500.1 - 0.0012 18.1 3.5 0.0012 18.1 3.5 3.3 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.7 KZN94500.1 - 1.2 9.3 10.7 8.7 6.5 10.7 2.1 1 1 0 1 1 1 0 Double zinc ribbon WD40 PF00400.32 KZN94501.1 - 3.3e-50 167.0 30.2 3.8e-06 27.5 0.2 12.2 12 0 0 12 12 12 11 WD domain, G-beta repeat Utp12 PF04003.12 KZN94501.1 - 1.7e-21 76.5 0.2 3.5e-21 75.5 0.2 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KZN94501.1 - 1.2e-19 70.3 4.3 0.1 12.9 0.0 9.6 7 3 3 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KZN94501.1 - 1.9e-07 30.4 0.4 0.97 8.3 0.0 5.3 4 2 1 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KZN94501.1 - 3.3e-07 29.3 1.8 0.081 11.6 0.0 5.5 5 1 1 6 6 6 3 Nucleoporin Nup120/160 Frtz PF11768.8 KZN94501.1 - 0.0039 15.6 0.0 0.14 10.4 0.0 2.5 2 1 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KZN94501.1 - 0.035 13.4 0.0 14 4.9 0.0 3.3 3 0 0 3 3 3 0 WD40-like domain Nucleoporin_N PF08801.11 KZN94501.1 - 0.059 12.1 0.5 5.6 5.6 0.0 3.9 3 1 0 4 4 4 0 Nup133 N terminal like Utp13 PF08625.11 KZN94501.1 - 0.077 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Hira PF07569.11 KZN94501.1 - 0.17 11.6 0.5 5.7 6.6 0.0 3.4 4 0 0 4 4 4 0 TUP1-like enhancer of split P34-Arc PF04045.14 KZN94502.1 - 1e-107 359.3 0.1 1.3e-107 359.0 0.1 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc WD40 PF00400.32 KZN94503.1 - 1.4e-17 63.7 7.3 0.0015 19.4 0.2 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN94503.1 - 1.2e-07 31.9 1.0 0.028 14.7 0.1 4.9 3 1 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KZN94503.1 - 2.3e-07 29.9 1.4 0.00013 20.7 0.5 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KZN94503.1 - 0.015 14.0 0.0 1.7 7.3 0.0 2.6 2 1 1 3 3 3 0 Nup133 N terminal like Cmc1 PF08583.10 KZN94504.1 - 1.7e-17 63.2 4.4 2.1e-17 62.9 4.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Fcf1 PF04900.12 KZN94505.1 - 2.7e-19 69.4 0.1 4.9e-11 42.9 0.0 2.4 2 0 0 2 2 2 2 Fcf1 PP2C PF00481.21 KZN94506.1 - 0.00053 19.7 0.0 0.21 11.2 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 KZN94506.1 - 0.0051 16.8 0.0 0.022 14.7 0.0 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Beta-lactamase PF00144.24 KZN94508.1 - 4.1e-41 141.3 0.8 5.5e-41 140.9 0.8 1.2 1 0 0 1 1 1 1 Beta-lactamase DIE2_ALG10 PF04922.12 KZN94509.1 - 9.8e-124 413.6 0.4 1.5e-123 413.0 0.4 1.3 1 0 0 1 1 1 1 DIE2/ALG10 family Sld5 PF05916.11 KZN94510.1 - 3.1e-34 117.7 0.0 6.4e-34 116.7 0.0 1.5 1 1 0 1 1 1 1 GINS complex protein CUE PF02845.16 KZN94511.1 - 4.9e-11 42.1 0.0 7.6e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 CUE domain G2BR PF18442.1 KZN94511.1 - 0.01 15.4 10.7 0.017 14.7 10.7 1.3 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) HTH_32 PF13565.6 KZN94511.1 - 0.014 16.0 0.2 0.99 10.1 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain SMC_N PF02463.19 KZN94512.1 - 1.5e-65 220.8 17.9 1.1e-64 217.9 17.9 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KZN94512.1 - 8.7e-20 71.2 0.4 8.7e-20 71.2 0.4 3.2 4 0 0 4 4 4 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KZN94512.1 - 1.5e-12 48.4 7.9 1.5e-12 48.4 7.9 6.9 2 2 4 6 6 6 1 AAA domain AAA_21 PF13304.6 KZN94512.1 - 7.9e-10 39.0 8.0 0.0002 21.3 0.2 3.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KZN94512.1 - 0.00014 21.5 0.1 0.00034 20.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain HIP1_clath_bdg PF16515.5 KZN94512.1 - 0.0041 17.7 13.2 0.0041 17.7 13.2 9.6 2 2 7 10 10 10 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Methyltransf_25 PF13649.6 KZN94513.1 - 2.8e-13 50.4 0.0 5.1e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN94513.1 - 1.4e-10 41.7 0.0 2.6e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KZN94513.1 - 3.6e-10 39.6 0.0 5.5e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KZN94513.1 - 5e-10 39.4 0.0 6.8e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN94513.1 - 5.7e-07 30.2 0.0 8.9e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KZN94513.1 - 4.1e-06 26.7 0.0 6.1e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KZN94513.1 - 0.027 14.0 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 KZN94513.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain NOT2_3_5 PF04153.18 KZN94514.1 - 6.4e-27 94.2 0.0 1.8e-26 92.8 0.0 1.7 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family MRP-L47 PF06984.13 KZN94515.1 - 1.4e-20 73.2 0.0 2.2e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Clc-like PF07062.12 KZN94515.1 - 0.0069 15.9 0.8 0.011 15.2 0.8 1.3 1 0 0 1 1 1 1 Clc-like GDI PF00996.18 KZN94516.1 - 4.6e-192 638.3 0.0 5.4e-192 638.1 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KZN94516.1 - 0.026 14.8 0.0 0.086 13.1 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KZN94516.1 - 0.068 13.7 0.3 0.56 10.8 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 4HBT PF03061.22 KZN94517.1 - 1.6e-12 47.6 0.0 2.3e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KZN94517.1 - 3.9e-05 24.0 0.0 5.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Glyco_hydro_47 PF01532.20 KZN94517.1 - 0.26 10.1 0.0 0.34 9.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 47 ORC4_C PF14629.6 KZN94518.1 - 5.5e-49 166.5 0.0 8.2e-49 165.9 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 KZN94518.1 - 1.7e-15 57.8 0.1 4.5e-15 56.4 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KZN94518.1 - 9.7e-09 35.8 0.0 2.7e-08 34.3 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KZN94518.1 - 1.2e-06 28.6 0.0 4e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 KZN94518.1 - 2.3e-05 24.4 0.0 5.5e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KZN94518.1 - 3.3e-05 24.2 0.0 7.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 KZN94518.1 - 7.6e-05 22.1 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain DUF815 PF05673.13 KZN94518.1 - 0.00013 21.2 0.0 0.00022 20.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 KZN94518.1 - 0.0051 17.1 0.0 0.0097 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.25 KZN94518.1 - 0.0088 15.7 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 KZN94518.1 - 0.0097 15.4 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 KZN94518.1 - 0.025 14.6 0.0 0.085 12.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.27 KZN94518.1 - 0.034 14.7 0.0 0.091 13.3 0.0 1.7 2 0 0 2 2 1 0 ABC transporter PIF1 PF05970.14 KZN94518.1 - 0.034 13.3 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase NB-ARC PF00931.22 KZN94518.1 - 0.045 12.9 0.0 0.082 12.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain TniB PF05621.11 KZN94518.1 - 0.16 11.3 0.0 2.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein Sigma70_ner PF04546.13 KZN94518.1 - 1.1 9.1 7.5 2.6 7.9 7.1 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region Astro_capsid_p PF12226.8 KZN94518.1 - 5 6.2 8.9 9.2 5.3 8.9 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RGS PF00615.19 KZN94519.1 - 6.4e-35 120.0 0.1 1.4e-34 118.9 0.1 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 KZN94519.1 - 8.8e-26 89.8 0.1 8.7e-20 70.6 0.0 3.5 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Glyco_tran_WbsX PF14307.6 KZN94519.1 - 0.19 11.2 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase WbsX DUF1304 PF06993.12 KZN94519.1 - 0.23 11.5 0.0 0.54 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) CDC73_C PF05179.14 KZN94520.1 - 1.2e-56 190.7 0.0 2.1e-56 190.0 0.0 1.4 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal MFS_1 PF07690.16 KZN94520.1 - 4.1e-13 49.0 37.9 4.1e-13 49.0 37.9 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily SET PF00856.28 KZN94521.1 - 4.2e-07 30.5 0.2 1e-06 29.2 0.0 1.8 2 0 0 2 2 2 1 SET domain PHD PF00628.29 KZN94521.1 - 7.9e-06 25.7 9.2 1.5e-05 24.8 9.2 1.5 1 0 0 1 1 1 1 PHD-finger DEC-1_N PF04625.13 KZN94521.1 - 9.2 5.2 16.9 16 4.4 16.9 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region AA_permease PF00324.21 KZN94522.1 - 3.1e-52 177.8 35.6 1.5e-51 175.5 35.6 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KZN94522.1 - 5.3e-15 55.2 31.8 9.5e-15 54.3 31.8 1.4 1 1 0 1 1 1 1 Amino acid permease WD40 PF00400.32 KZN94523.1 - 7.7e-13 48.7 12.7 0.00075 20.3 0.6 5.0 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KZN94523.1 - 2.5e-05 24.5 0.2 0.28 11.5 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KZN94523.1 - 0.02 13.9 0.1 6.8 5.6 0.0 3.1 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF3362 PF11842.8 KZN94523.1 - 0.098 13.0 0.8 0.24 11.7 0.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3362) Rav1p_C PF12234.8 KZN94523.1 - 0.13 10.6 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 RAVE protein 1 C terminal Glycos_transf_4 PF00953.21 KZN94524.1 - 1.8e-31 109.3 10.8 1.8e-31 109.3 10.8 2.4 3 1 0 3 3 3 1 Glycosyl transferase family 4 SecE PF00584.20 KZN94524.1 - 2.4 8.1 0.0 2.4 8.1 0.0 4.7 5 0 0 5 5 5 0 SecE/Sec61-gamma subunits of protein translocation complex SLATT_1 PF18181.1 KZN94524.1 - 7.6 6.5 5.0 1.6 8.7 0.8 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 MFS_1 PF07690.16 KZN94525.1 - 4.8e-08 32.3 32.8 4.8e-08 32.3 32.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KZN94525.1 - 2e-07 30.8 3.5 2e-07 30.8 3.5 2.5 2 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 Phage_holin_3_1 PF05106.12 KZN94525.1 - 6.7 7.2 8.1 1.2 9.6 0.8 2.9 2 1 1 3 3 3 0 Phage holin family (Lysis protein S) ADH_zinc_N PF00107.26 KZN94526.1 - 2.9e-11 43.4 0.0 5e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KZN94526.1 - 0.0001 23.3 0.0 0.00019 22.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KZN94526.1 - 0.0027 17.6 0.0 0.0052 16.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF4567 PF15131.6 KZN94526.1 - 0.12 12.4 1.8 0.61 10.2 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4567) Aconitase PF00330.20 KZN94527.1 - 9.6e-161 535.9 0.1 1.2e-160 535.6 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KZN94527.1 - 8.6e-40 136.1 0.0 1.7e-39 135.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Alpha-amylase PF00128.24 KZN94528.1 - 8.4e-16 58.4 1.4 4.1e-15 56.2 1.4 2.2 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 KZN94528.1 - 6.9e-14 52.1 0.2 1.1e-13 51.4 0.2 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KZN94528.1 - 0.00057 19.5 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pribosyltran PF00156.27 KZN94529.1 - 2.8e-14 52.9 0.3 4.2e-14 52.4 0.3 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain MTHFR PF02219.17 KZN94530.1 - 1.3e-115 385.7 0.0 2e-115 385.0 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase MeaB PF03308.16 KZN94530.1 - 0.13 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Peptidase_C23 PF05379.11 KZN94531.1 - 0.0055 16.8 0.1 0.011 15.8 0.1 1.5 1 0 0 1 1 1 1 Carlavirus endopeptidase DUF4515 PF14988.6 KZN94531.1 - 0.052 13.4 1.5 0.076 12.8 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) DUF2418 PF10332.9 KZN94532.1 - 6.8e-38 129.1 0.4 1.7e-37 127.8 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) ATP-synt_F PF01990.17 KZN94533.1 - 1.5e-33 115.0 0.0 1.7e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF257 PF03192.13 KZN94533.1 - 0.17 11.6 0.0 0.22 11.3 0.0 1.1 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 E1_DerP2_DerF2 PF02221.15 KZN94534.1 - 1.6e-28 99.8 0.3 2.2e-28 99.3 0.3 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 KZN94534.1 - 0.00011 22.5 0.0 0.00022 21.6 0.0 1.4 1 1 0 1 1 1 1 ML-like domain AMP-binding PF00501.28 KZN94535.1 - 4.9e-60 203.3 0.0 6.6e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KZN94535.1 - 0.0012 19.8 0.1 0.0025 18.7 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.23 KZN94536.1 - 4.8e-63 212.9 0.8 8.7e-63 212.1 0.8 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KZN94536.1 - 1.5e-42 144.2 0.1 3.2e-42 143.1 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KZN94536.1 - 0.0025 17.5 1.3 0.0089 15.6 1.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KZN94536.1 - 0.0026 17.6 1.4 0.11 12.4 0.2 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 KZN94536.1 - 0.022 14.9 0.0 0.084 13.1 0.0 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal APH PF01636.23 KZN94537.1 - 4.4e-06 26.8 2.0 5.1e-06 26.6 0.2 2.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family Arv1 PF04161.13 KZN94538.1 - 2.6e-60 204.2 0.0 2.4e-51 174.9 0.0 2.4 2 0 0 2 2 2 2 Arv1-like family ATP_synt_H PF05493.13 KZN94539.1 - 1e-23 83.6 1.3 1.1e-23 83.4 1.3 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Anoctamin PF04547.12 KZN94539.1 - 0.6 8.9 3.9 0.71 8.6 3.9 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel PsbX PF06596.11 KZN94539.1 - 3.5 7.7 7.9 0.94 9.5 2.1 2.4 2 1 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) BAR_2 PF10455.9 KZN94540.1 - 4.8e-62 209.7 1.5 6.7e-62 209.2 1.5 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KZN94540.1 - 2.8e-20 73.0 8.2 4.7e-19 69.0 8.2 2.0 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 KZN94540.1 - 0.0026 17.5 2.4 0.019 14.6 0.2 2.3 2 0 0 2 2 2 1 BAR domain of APPL family DUF4111 PF13427.6 KZN94540.1 - 0.012 15.8 0.2 0.061 13.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4111) TPR_19 PF14559.6 KZN94540.1 - 0.13 12.8 5.2 2.2 8.8 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Fungal_trans_2 PF11951.8 KZN94542.1 - 1.5e-19 70.1 0.0 4.7e-14 52.0 0.2 3.2 3 0 0 3 3 3 3 Fungal specific transcription factor domain Zn_clus PF00172.18 KZN94542.1 - 6.1e-07 29.5 9.9 1.1e-06 28.7 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_8 PF05148.15 KZN94543.1 - 2.8e-54 184.3 0.0 1e-51 175.9 0.0 2.7 3 0 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KZN94543.1 - 6.8e-06 26.6 0.0 2e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN94543.1 - 0.0018 19.0 0.0 0.057 14.1 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain DUF4551 PF15087.6 KZN94543.1 - 2.7 6.7 15.6 4.7 5.9 15.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Totivirus_coat PF05518.11 KZN94543.1 - 3.7 5.5 16.1 6 4.8 16.1 1.2 1 0 0 1 1 1 0 Totivirus coat protein Proteasome PF00227.26 KZN94544.1 - 9.7e-58 194.8 0.1 1.2e-57 194.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KZN94544.1 - 7.9e-09 35.0 0.2 2.1e-08 33.7 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature GCP_N_terminal PF17681.1 KZN94545.1 - 5.1e-65 220.1 0.0 8.5e-65 219.4 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KZN94545.1 - 6.3e-59 200.0 4.4 6.3e-59 200.0 4.4 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal CLZ PF16526.5 KZN94545.1 - 0.22 11.9 9.9 0.047 14.1 1.5 3.0 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Methyltransf_23 PF13489.6 KZN94547.1 - 3.7e-13 49.6 0.0 5.6e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KZN94547.1 - 4.8e-12 46.4 0.0 1.8e-11 44.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KZN94547.1 - 5.8e-11 42.9 0.0 1.4e-10 41.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KZN94547.1 - 8e-08 32.9 0.0 4.1e-07 30.7 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KZN94547.1 - 1.3e-06 28.3 0.0 1.5e-05 24.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KZN94547.1 - 8.3e-05 22.1 0.0 0.0012 18.3 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.18 KZN94547.1 - 0.00038 19.9 0.0 0.002 17.5 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 KZN94547.1 - 0.002 16.8 0.0 0.015 13.9 0.0 1.9 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TPMT PF05724.11 KZN94547.1 - 0.04 13.6 0.0 0.35 10.5 0.0 2.0 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_2 PF00891.18 KZN94547.1 - 0.17 11.1 0.0 1.2 8.4 0.0 1.9 2 0 0 2 2 2 0 O-methyltransferase domain KH_8 PF17903.1 KZN94548.1 - 2.3e-32 110.9 1.2 3e-32 110.5 0.0 1.9 2 0 0 2 2 2 1 Krr1 KH1 domain Exo5 PF09810.9 KZN94548.1 - 0.0026 17.3 3.2 0.0039 16.7 3.2 1.3 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease KH_1 PF00013.29 KZN94548.1 - 0.011 15.5 0.0 0.035 13.9 0.0 1.9 1 1 0 1 1 1 0 KH domain Asp-B-Hydro_N PF05279.11 KZN94548.1 - 7.6 6.5 29.5 14 5.7 29.5 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region ATG22 PF11700.8 KZN94549.1 - 2.2e-131 438.8 29.8 2.5e-131 438.6 29.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KZN94549.1 - 3.3e-09 36.1 36.9 5.7e-06 25.5 8.4 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily VbhA PF18495.1 KZN94549.1 - 0.043 13.7 0.2 0.079 12.8 0.2 1.3 1 0 0 1 1 1 0 Antitoxin VbhA Glyco_transf_90 PF05686.12 KZN94550.1 - 1.2e-27 96.8 0.1 1.7e-27 96.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 KZN94550.1 - 0.071 13.5 0.0 0.2 12.1 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferases group 1 MU117 PF15474.6 KZN94551.1 - 4.7e-14 53.0 8.5 6.8e-14 52.5 8.5 1.2 1 0 0 1 1 1 1 Meiotically up-regulated gene family DUF3632 PF12311.8 KZN94552.1 - 3.9e-31 108.8 0.1 5.1e-31 108.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Glyco_hydro_17 PF00332.18 KZN94553.1 - 7.8e-05 22.4 0.3 0.00014 21.6 0.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 DAP_B PF07930.12 KZN94554.1 - 1.1e-72 243.9 0.0 1.5e-72 243.4 0.0 1.2 1 0 0 1 1 1 1 D-aminopeptidase, domain B Beta-lactamase PF00144.24 KZN94554.1 - 2.2e-41 142.2 0.0 3.1e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase WaaY PF06176.11 KZN94555.1 - 0.013 15.1 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) DUF2196 PF09962.9 KZN94556.1 - 3.1e-22 78.3 1.0 4.7e-22 77.7 0.3 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2196) Flavoprotein PF02441.19 KZN94557.1 - 4.7e-46 156.4 0.0 7.8e-46 155.7 0.0 1.3 1 1 0 1 1 1 1 Flavoprotein adh_short PF00106.25 KZN94558.1 - 5.6e-37 127.1 0.0 7.9e-37 126.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KZN94558.1 - 9.7e-23 80.9 0.0 1.3e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KZN94558.1 - 0.00018 21.5 0.0 0.00035 20.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KZN94558.1 - 0.03 13.5 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Erg28 PF03694.13 KZN94559.1 - 1.9e-37 128.0 1.1 2.2e-37 127.8 1.1 1.1 1 0 0 1 1 1 1 Erg28 like protein GalP_UDP_transf PF01087.22 KZN94560.1 - 3.3e-70 236.3 0.2 4.8e-69 232.5 0.2 2.2 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KZN94560.1 - 8.9e-60 201.2 0.1 2.7e-59 199.6 0.1 1.7 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4921 PF16268.5 KZN94560.1 - 0.0016 17.4 0.0 0.19 10.5 0.0 2.6 2 1 1 3 3 3 2 Domain of unknown function (DUF4921) HIT PF01230.23 KZN94560.1 - 0.15 12.8 0.0 0.6 10.9 0.0 2.0 2 1 0 2 2 2 0 HIT domain TRAP-gamma PF07074.12 KZN94560.1 - 0.17 11.4 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) F-box-like PF12937.7 KZN94561.1 - 1.3e-06 28.1 0.6 3.2e-06 26.9 0.6 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KZN94561.1 - 0.0017 18.2 0.9 0.0048 16.7 0.9 1.9 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KZN94561.1 - 0.077 12.9 0.2 0.17 11.8 0.2 1.5 1 0 0 1 1 1 0 F-box MFS_1 PF07690.16 KZN94562.1 - 2e-42 145.4 52.0 2.1e-42 145.3 46.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KZN94562.1 - 1.7e-07 30.5 24.4 7.9e-07 28.3 24.4 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter DSBA PF01323.20 KZN94563.1 - 8.3e-20 71.4 0.0 9.2e-20 71.2 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain NAD_binding_2 PF03446.15 KZN94564.1 - 2e-28 99.5 0.0 3.1e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KZN94564.1 - 1.2e-07 32.0 0.1 3.3e-07 30.6 0.1 1.8 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KZN94564.1 - 2.7e-07 31.1 0.0 5.9e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KZN94564.1 - 1.9e-06 28.0 0.0 4.1e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 KZN94564.1 - 0.015 14.9 0.3 0.14 11.7 0.0 2.1 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 KZN94564.1 - 0.021 15.1 0.0 0.038 14.2 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain IlvN PF07991.12 KZN94564.1 - 0.05 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 KZN94564.1 - 0.11 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sugar_tr PF00083.24 KZN94565.1 - 1.1e-138 462.9 30.8 1.2e-138 462.7 30.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN94565.1 - 2.2e-27 95.9 48.9 5.4e-23 81.5 30.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 KZN94565.1 - 0.014 15.6 2.0 0.014 15.6 2.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2530) NOG1_N PF17835.1 KZN94566.1 - 9.1e-49 165.5 1.0 1.7e-48 164.6 0.1 2.0 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 KZN94566.1 - 5.1e-27 93.6 3.3 1.3e-26 92.3 3.3 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 KZN94566.1 - 9.3e-26 89.4 0.2 1.9e-25 88.4 0.2 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 KZN94566.1 - 8.4e-16 58.1 0.0 1.9e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KZN94566.1 - 2.1e-07 30.6 0.0 6.6e-07 29.0 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KZN94566.1 - 0.0029 17.5 0.3 1.2 9.0 0.1 3.1 3 1 0 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 KZN94566.1 - 0.0063 16.6 0.0 4 7.4 0.0 2.6 1 1 0 2 2 2 2 Dynamin family AAA_16 PF13191.6 KZN94566.1 - 0.0091 16.4 0.3 0.32 11.4 0.0 3.2 4 0 0 4 4 4 1 AAA ATPase domain Gtr1_RagA PF04670.12 KZN94566.1 - 0.052 12.9 0.0 0.092 12.1 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Acetyltransf_1 PF00583.25 KZN94567.1 - 3.2e-14 53.2 0.0 5.7e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KZN94567.1 - 5.2e-13 49.1 0.0 7.6e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KZN94567.1 - 2.3e-10 40.7 0.0 3.8e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KZN94567.1 - 0.0028 17.7 0.0 0.005 16.9 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KZN94567.1 - 0.0035 17.4 0.0 0.0082 16.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KZN94567.1 - 0.018 15.0 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein PYST-C1 PF09690.10 KZN94567.1 - 0.068 12.9 0.6 0.16 11.8 0.6 1.6 1 1 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) NAT PF04768.13 KZN94568.1 - 1.6e-52 177.6 0.0 2.5e-51 173.7 0.0 2.4 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase KR PF08659.10 KZN94569.1 - 3.8e-17 62.8 0.0 7.4e-17 61.8 0.0 1.5 2 0 0 2 2 2 1 KR domain PP-binding PF00550.25 KZN94569.1 - 0.00021 21.6 0.0 0.00052 20.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 KZN94570.1 - 2.9e-07 30.6 0.1 3.7e-07 30.2 0.1 1.1 1 0 0 1 1 1 1 KR domain ADH_zinc_N_2 PF13602.6 KZN94570.1 - 0.055 14.5 0.0 0.1 13.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DPM3 PF08285.11 KZN94571.1 - 0.013 15.7 0.1 0.013 15.7 0.1 2.2 2 1 1 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF5379 PF17350.2 KZN94571.1 - 0.053 13.8 2.0 9.8 6.5 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5379) DUF2070 PF09843.9 KZN94571.1 - 1 7.6 4.8 0.78 8.0 2.9 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) PrgI PF12666.7 KZN94571.1 - 1.2 9.9 0.0 1.2 9.9 0.0 3.2 2 1 1 3 3 3 0 PrgI family protein Sugar_tr PF00083.24 KZN94572.1 - 4e-85 286.4 25.9 4.6e-85 286.2 25.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KZN94572.1 - 6.3e-19 68.1 22.0 1.5e-18 66.8 12.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC2_membrane_4 PF12730.7 KZN94572.1 - 7.8 6.4 16.7 0.3 11.0 0.1 3.9 3 2 0 3 3 3 0 ABC-2 family transporter protein # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Penicillium_chrysogenum-ASM71027v1/GCA_000710275.1_ASM71027v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Penicillium_chrysogenum-ASM71027v1/GCA_000710275.1_ASM71027v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Penicillium_chrysogenum-ASM71027v1/GCA_000710275.1_ASM71027v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Penicillium_chrysogenum-ASM71027v1/GCA_000710275.1_ASM71027v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 02:40:07 2019 # [ok]